WorldWideScience

Sample records for lost palaeobiogeography evolution

  1. Dragon's paradise lost: palaeobiogeography, evolution and extinction of the largest-ever terrestrial lizards (Varanidae.

    Directory of Open Access Journals (Sweden)

    Scott A Hocknull

    Full Text Available BACKGROUND: The largest living lizard species, Varanus komodoensis Ouwens 1912, is vulnerable to extinction, being restricted to a few isolated islands in eastern Indonesia, between Java and Australia, where it is the dominant terrestrial carnivore. Understanding how large-bodied varanids responded to past environmental change underpins long-term management of V. komodoensis populations. METHODOLOGY/PRINCIPAL FINDINGS: We reconstruct the palaeobiogeography of Neogene giant varanids and identify a new (unnamed species from the island of Timor. Our data reject the long-held perception that V. komodoensis became a giant because of insular evolution or as a specialist hunter of pygmy Stegodon. Phyletic giantism, coupled with a westward dispersal from mainland Australia, provides the most parsimonious explanation for the palaeodistribution of V. komodoensis and the newly identified species of giant varanid from Timor. Pliocene giant varanid fossils from Australia are morphologically referable to V. komodoensis suggesting an ultimate origin for V. komodoensis on mainland Australia (>3.8 million years ago. Varanus komodoensis body size has remained stable over the last 900,000 years (ka on Flores, a time marked by major faunal turnovers, extinction of the island's megafauna, the arrival of early hominids by 880 ka, co-existence with Homo floresiensis, and the arrival of modern humans by 10 ka. Within the last 2000 years their populations have contracted severely. CONCLUSIONS/SIGNIFICANCE: Giant varanids were once a ubiquitous part of Subcontinental Eurasian and Australasian faunas during the Neogene. Extinction played a pivotal role in the reduction of their ranges and diversity throughout the late Quaternary, leaving only V. komodoensis as an isolated long-term survivor. The events over the last two millennia now threaten its future survival.

  2. Geologic evolution of the Lost City Hydrothermal Field

    Science.gov (United States)

    Denny, Alden R.; Kelley, Deborah S.; Früh-Green, Gretchen L.

    2016-02-01

    The Lost City Hydrothermal Field (LCHF) is a novel serpentinite-hosted vent field located on the Atlantis Massif southern wall. Results of 2 m resolution bathymetry, side scan, and video and still imagery, integrated with direct submersible observations provide the first high-resolution geologic map of the LCHF. These data form the foundation for an evolutionary model for the vent system over the past >120,000 years. The field is located on a down-dropped bench 70 m below the summit of the massif. The bench is capped by breccia and pelagic carbonate deposits underlain by variably deformed and altered serpentinite and gabbroic rocks. Hydrothermal activity is focused at the 60 m tall, 100 m across, massive carbonate edifice "Poseidon," which is venting 91°C fluid. Hydrothermal activity declines south and west of the Poseidon complex and dies off completely at distances greater than 200 m. East of Poseidon, the most recent stage of hydrothermal flow is characterized by egress of diffuse fluids from narrow fissures within a low-angle, anastomosing mylonite zone. South of the area of current hydrothermal activity, there is evidence of two discrete previously unrecognized relict fields. Active venting sites defined by carbonate-filled fissures that cut the carbonate cap rock at the summit of the massif mark the present-day northernmost extent of venting. These spatial relationships reflect multiple stages of field development, the northward migration of venting over time, and the likely development of a nascent field at the massif summit.

  3. The palaeobiogeography of South American gomphotheres

    Directory of Open Access Journals (Sweden)

    Spencer G. Lucas

    2013-01-01

    Full Text Available Gomphotheriid proboscideans reached South America as Late Cenozoic immigrants from North America. However, disagreements over alpha taxonomy, age dating and phylogenetic relationships have produced three competing hypotheses about this immigration: (1 a single gomphothere immigration took place soon after the ~3 Ma closure of the Panamanian isthmus; (2 two separate gomphothere immigrations took place after closure of the isthmus; or (3 an earlier, Late Miocene (before 9 Ma immigration brought gomphotheres into South America. A critical re-evaluation of the alpha taxonomy, age dating and phylogenetic relationships of Neotropical gomphotheres identifies two valid genera of South American gomphotheres, Cuvieronius and Notiomastodon (= “Haplomastodon”, = “Stegomastodon” from South America and recognizes “Amahuacatherium” as an invalid genus likely based on a specimen of Notiomastodon. The oldest well-dated South American gomphothere fossil is Marplatan, ~2.5 Ma, from Argentina. The case for an age of “Amahuacatherium” older than 9 Ma is refuted by mammalian biostratigraphy and a re-evaluation of the relevant magnetostratigraphy. North American Rhynchotherium descended from Gomphotherium during the Late Hemphillian (~5–6 Ma and gave rise to Cuvieronius in North America by the end of the Blancan (~2 Ma time. Notiomastodon evolved from Cuvieronius in South America during the Pleistocene. The case for a close relationship between the Neotropical gomphotheres and Sinomastodon from China is rejected. Central America was not a center of endemic gomphothere evolution and merely acted as a pathway for the immigration of gomphotheres from north to south: Gomphotherium into Central America during the Miocene, Cuvieronius to Central America by Early Pleistocene time and on to South America. After closure of the Panamanian isthmus, Cuvieronius immigrated to South America, where it gave rise to Notiomastodon by Middle Pleistocene time. The

  4. U12 type introns were lost at multiple occasions during evolution

    Directory of Open Access Journals (Sweden)

    Bartschat Sebastian

    2010-02-01

    Full Text Available Abstract Background Two categories of introns are known, a common U2 type and a rare U12 type. These two types of introns are removed by distinct spliceosomes. The phylogenetic distribution of spliceosomal RNAs that are characteristic of the U12 spliceosome, i.e. the U11, U12, U4atac and U6atac RNAs, suggest that U12 spliceosomes were lost in many phylogenetic groups. We have now examined the distribution of U2 and U12 introns in many of these groups. Results U2 and U12 introns were predicted by making use of available EST and genomic sequences. The results show that in species or branches where U12 spliceosomal components are missing, also U12 type of introns are lacking. Examples are the choanoflagellate Monosiga brevicollis, Entamoeba histolytica, green algae, diatoms, and the fungal lineage Basidiomycota. Furthermore, whereas U12 splicing does not occur in Caenorhabditis elegans, U12 introns as well as U12 snRNAs are present in Trichinella spiralis, which is deeply branching in the nematode tree. A comparison of homologous genes in T. spiralis and C. elegans revealed different mechanisms whereby U12 introns were lost. Conclusions The phylogenetic distribution of U12 introns and spliceosomal RNAs give further support to an early origin of U12 dependent splicing. In addition, this distribution identifies a large number of instances during eukaryotic evolution where such splicing was lost.

  5. New Australian sauropods shed light on Cretaceous dinosaur palaeobiogeography

    Science.gov (United States)

    Poropat, Stephen F.; Mannion, Philip D.; Upchurch, Paul; Hocknull, Scott A.; Kear, Benjamin P.; Kundrát, Martin; Tischler, Travis R.; Sloan, Trish; Sinapius, George H. K.; Elliott, Judy A.; Elliott, David A.

    2016-01-01

    Australian dinosaurs have played a rare but controversial role in the debate surrounding the effect of Gondwanan break-up on Cretaceous dinosaur distribution. Major spatiotemporal gaps in the Gondwanan Cretaceous fossil record, coupled with taxon incompleteness, have hindered research on this effect, especially in Australia. Here we report on two new sauropod specimens from the early Late Cretaceous of Queensland, Australia, that have important implications for Cretaceous dinosaur palaeobiogeography. Savannasaurus elliottorum gen. et sp. nov. comprises one of the most complete Cretaceous sauropod skeletons ever found in Australia, whereas a new specimen of Diamantinasaurus matildae includes the first ever cranial remains of an Australian sauropod. The results of a new phylogenetic analysis, in which both Savannasaurus and Diamantinasaurus are recovered within Titanosauria, were used as the basis for a quantitative palaeobiogeographical analysis of macronarian sauropods. Titanosaurs achieved a worldwide distribution by at least 125 million years ago, suggesting that mid-Cretaceous Australian sauropods represent remnants of clades which were widespread during the Early Cretaceous. These lineages would have entered Australasia via dispersal from South America, presumably across Antarctica. High latitude sauropod dispersal might have been facilitated by Albian–Turonian warming that lifted a palaeoclimatic dispersal barrier between Antarctica and South America. PMID:27763598

  6. Digits lost or gained? Evidence for pedal evolution in the dwarf salamander complex (Eurycea, Plethodontidae.

    Directory of Open Access Journals (Sweden)

    Trip Lamb

    Full Text Available Change in digit number, particularly digit loss, has occurred repeatedly over the evolutionary history of tetrapods. Although digit loss has been documented among distantly related species of salamanders, it is relatively uncommon in this amphibian order. For example, reduction from five to four toes appears to have evolved just three times in the morphologically and ecologically diverse family Plethodontidae. Here we report a molecular phylogenetic analysis for one of these four-toed lineages--the Eurycea quadridigitata complex (dwarf salamanders--emphasizing relationships to other species in the genus. A multilocus phylogeny reveals that dwarf salamanders are paraphyletic with respect to a complex of five-toed, paedomorphic Eurycea from the Edwards Plateau in Texas. We use this phylogeny to examine evolution of digit number within the dwarf-Edwards Plateau clade, testing contrasting hypotheses of digit loss (parallelism among dwarf salamanders versus digit gain (re-evolution in the Edwards Plateau complex. Bayes factors analysis provides statistical support for a five-toed common ancestor at the dwarf-Edwards node, favoring, slightly, the parallelism hypothesis for digit loss. More importantly, our phylogenetic results pinpoint a rare event in the pedal evolution of plethodontid salamanders.

  7. Has snake fang evolution lost its bite? New insights from a structural mechanics viewpoint.

    Science.gov (United States)

    Broeckhoven, Chris; du Plessis, Anton

    2017-08-01

    Venomous snakes-the pinnacle of snake evolution-are characterized by their possession of venom-conducting fangs ranging from grooved phenotypes characterizing multiple lineages of rear-fanged taxa to tubular phenotypes present in elapids, viperids and atractaspidines. Despite extensive research, controversy still exists on the selective pressures involved in fang phenotype diversification. Here, we test the hypothesis that larger fangs and consequently a shift to an anterior position in the maxilla evolved to compensate for the costs of structural changes, i.e. higher stress upon impact in tubular fangs compared to grooved fangs. Direct voxel-based stress simulations conducted on high-resolution µCT scans, analysed within a phylogenetic framework, showed no differences in stress distribution between the three fang phenotypes, despite differences in (relative) fang length. These findings suggest that additional compensatory mechanisms are responsible for the biomechanical optimization and that fang length might instead be related to differential striking behaviour strategies. © 2017 The Author(s).

  8. The sedentary (r)evolution: Have we lost our metabolic flexibility?

    Science.gov (United States)

    Freese, Jens; Klement, Rainer Johannes; Ruiz-Núñez, Begoña; Schwarz, Sebastian; Lötzerich, Helmut

    2018-01-01

    During the course of evolution, up until the agricultural revolution, environmental fluctuations forced the human species to develop a flexible metabolism in order to adapt its energy needs to various climate, seasonal and vegetation conditions. Metabolic flexibility safeguarded human survival independent of food availability. In modern times, humans switched their primal lifestyle towards a constant availability of energy-dense, yet often nutrient-deficient, foods, persistent psycho-emotional stressors and a lack of exercise. As a result, humans progressively gain metabolic disorders, such as the metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease, certain types of cancer, cardiovascular disease and Alzheimer´s disease, wherever the sedentary lifestyle spreads in the world. For more than 2.5 million years, our capability to store fat for times of food shortage was an outstanding survival advantage. Nowadays, the same survival strategy in a completely altered surrounding is responsible for a constant accumulation of body fat. In this article, we argue that the metabolic disease epidemic is largely based on a deficit in metabolic flexibility. We hypothesize that the modern energetic inflexibility, typically displayed by symptoms of neuroglycopenia, can be reversed by re-cultivating suppressed metabolic programs, which became obsolete in an affluent environment, particularly the ability to easily switch to ketone body and fat oxidation. In a simplified model, the basic metabolic programs of humans’ primal hunter-gatherer lifestyle are opposed to the current sedentary lifestyle. Those metabolic programs, which are chronically neglected in modern surroundings, are identified and conclusions for the prevention of chronic metabolic diseases are drawn. PMID:29225776

  9. Clubbed fingers: the claws we lost?

    NARCIS (Netherlands)

    Brouwers, A.A.M.; Vermeij-Keers, C.; Zoelen, E.J.J. van; Gooren, L.J.G.

    2004-01-01

    Clubbed digits resemble the human embryonic fingers and toes, which took like the digits of a claw. Clubbed digits, thus, may represent the return of the embryonic claw and may even represent the claws man has lost during evolution, if ontogenesis realty recapitulates phylogenesis. We put forward

  10. Lost in Location

    DEFF Research Database (Denmark)

    Hansen, Lone Koefoed

    2009-01-01

    traversed. While becoming destination aware, the individual loses her location awareness. The article proposes that the reason people get lost when using sat-nav is due to a wrong location-performative paradigm. As an alternative, the article introduces and analyzes two performance-related examples...... that illustrate an alternative location-performative paradigm: Meredith Warner's Lost/Found knitting series and Etter and Schecht's Melodious Walkabout. In both examples, the artist's hand becomes the intermediary between alien and location. Thus, by exploring how wayfinding can be a poetically situated...... performance, the article examines how the growing locative media industry can learn from the location-aware performative strategies employed by artists who create situated and urban performances for the curious participant. The academic frames employed in the analysis draw on psychogeography, site...

  11. Lost spoiler practices

    DEFF Research Database (Denmark)

    Gürsimsek, Ödül; Drotner, Kirsten

    2014-01-01

    narratives, and viewers through tracing, dismantling – and sometimes questioning – content in order to create coherent meanings in the maze of narratives. Online audiences, such as spoiler communities, may uncover components of transmedia storytelling, discuss their validity and enhance them with individual...... and documents that interactions between Lost audiences and producers operate as forms of social participation when spoiler-seeking audiences work to unravel, challenge and predict the narrative while the producers seek to orchestrate transmedia storytelling experiences. Our results serve as a sobering empirical...

  12. The Lost Guidewire

    Directory of Open Access Journals (Sweden)

    Ankit Shah

    2017-04-01

    Full Text Available History of present illness: A 44-year-old female called 911 complaining of abdominal pain, but was unresponsive upon arrival by emergency medical services (EMS. She presented to the emergency department (ED as a full cardiac arrest and had return of spontaneous circulation (ROSC with cardiopulmonary resuscitation (CPR and epinephrine. The patient had a splenic embolization 1 week prior to presentation. Bedside ultrasound demonstrated free fluid throughout the abdomen. As part of the resuscitation, femoral central venous access was obtained by the Emergency Department (ED physician, and a medical student was allowed to place a Cordis over the guidewire. The attending was next to the student, though became distracted when the patient again lost pulses. The student lost control of the guidewire upon re-initiation of CPR. Another Cordis was placed in the same location by the ED physician after the guidewire was seen on a chest radiograph. The patient was taken to the operating room with massive transfusion protocol, and the guidewire was left in the vena caval system until the patient could be stabilized. Two days later, interventional radiology removed the guidewire via a right internal jugular (IJ approach without complications. The patient had a prolonged and complicated course, but was discharged home two weeks later at her baseline. Significant findings: Initial chest radiograph shows a guidewire in the inferior vena cava (IVC, superior vena cava (SVC, and right IJ veins. Discussion: Central line complications include failure to place the catheter, improper catheter location, hemothorax from vascular injury, infection, arrhythmia, and cardiac arrest1. Complications from lost guidewires include cardiac dysrhythmias, cardiac conduction abnormalities, perforation of vessels/heart chambers, kinking/looping/knotting of the wire, entanglement of previously placed intravascular devices, breakage of the tip of the wire and subsequent embolization and

  13. Nostalgia and lost identity.

    Science.gov (United States)

    Pourtova, Elena

    2013-02-01

    Nostalgia for the Soviet Union is a major social phenomenon in Russia today due to the irrevocable losses of the recent past in which Soviet citizens involuntarily became immigrants in their own country. With reference to discussions of nostalgia in philosophical and psychoanalytic literature, I suggest that nostalgia may represent either a defensive regression to the past or a progressive striving for wholeness through re-connecting with what has been lost in the service of a greater integration. I compare this with the processes of adaptation seen in immigrants and provide a clinical illustration of a young man coming to terms with loss and change in the post-Soviet era. When nostalgia is recognized as a legitimate emotional experience it may facilitate mourning and enable the integration of the past with the present and the development of a new identity. © 2013, The Society of Analytical Psychology.

  14. Lost in translation?

    DEFF Research Database (Denmark)

    Granas, Anne Gerd; Nørgaard, Lotte Stig; Sporrong, Sofia Kälvemark

    2014-01-01

    OBJECTIVE: The "Beliefs about Medicines Questionnaire" (BMQ) assess balance of necessity and concern of medicines. The BMQ has been translated from English to many languages. However, the original meaning of statements, such as "My medicine is a mystery to me", may be lost in translation. The aim...... of this study is to compare three Scandinavian translations of the BMQ. (1) How reliable are the translations? (2) Are they still valid after translation? METHODS: Translated Norwegian, Swedish and Danish versions of the BMQ were scrutinized by three native Scandinavian researchers. Linguistic differences...... and ambiguities in the 5-point Likert scale and the BMQ statements were compared. RESULTS: In the Scandinavian translations, the Likert scale expanded beyond the original version at one endpoint (Swedish) or both endpoints (Danish). In the BMQ statements, discrepancies ranged from smaller inaccuracies toward...

  15. Lost in transformation?

    DEFF Research Database (Denmark)

    Norlyk, Annelise; Haahr, Anita; Dreyer, Pia

    2017-01-01

    and values from evidence-based medicine are being lost in the transformation into the current evidence-based hospital culture which potentially leads to a McDonaldization of nursing practice reflected as ‘one best way’. We argue for reviving ethics of care perspectives in today’s evidence practice...... as the fundamental values of nursing may potentially bridge conflicts between evidence-based practice and the ideals of patient participation thus preventing a practice of ‘McNursing’. Key words: nursing practice, evidence-based practice, nursing theory, nursing theorists, ethics of care, hospital culture, patient......Drawing on our previous empirical research, we provide an exemplary narrative to illustrate how patients have experienced hospital care organized according to evidence-based fast-track programmes. The aim of this paper is to analyse and discuss if and how it is possible to include patients...

  16. Lost in Translation

    Science.gov (United States)

    Lass, Wiebke; Reusswig, Fritz

    2014-05-01

    Lost in Translation? Introducing Planetary Boundaries into Social Systems. Fritz Reusswig, Wiebke Lass Potsdam Institute for Climate Impact Research, Potsdam, Germany Identifying and quantifying planetary boundaries by interdisciplinary science efforts is a challenging task—and a risky one, as the 1972 Limits to Growth publication has shown. Even if we may be assured that scientific understanding of underlying processes of the Earth system has significantly improved since then, the challenge of translating these findings into the social systems of the planet remains crucial for any kind of action, and in many respects far more challenging. We would like to conceptualize what could also be termed a problem of coupling social and natural systems as a nested set of social translation processes, well aware of the limited applicability of the language-related translation metaphor. Societies must, first, perceive these boundaries, and they have to understand their relevance. This includes, among many other things, the organization of transdisciplinary scientific cooperation. They will then have to translate this understood perception into possible actions, i.e. strategies for different local bodies, actors, and institutional settings. This implies a lot of 'internal' translation processes, e.g. from the scientific subsystem to the mass media, the political and the economic subsystem. And it implies to develop subsystem-specific schemes of evaluation for these alternatives, e.g. convincing narratives, cost-benefit analyses, or ethical legitimacy considerations. And, finally, societies do have to translate chosen action alternatives into monitoring and evaluation schemes, e.g. for agricultural production or renewable energies. This process includes the continuation of observing and re-analyzing the planetary boundary concept itself, as a re-adjustment of these boundaries in the light of new scientific insights cannot be excluded. Taken all together, societies may well

  17. Smartphone lost - Privacy gone

    CERN Multimedia

    Computer Security Team

    2012-01-01

    Who doesn't own an iPhone, Android or Blackberry mobile phone today? Lucky you if you don’t! In previous issues (Issue 06/07, 2012 and Issue 32/33/34, 2011) we have pointed out their lack of security. But what happens if you lose your smartphone or it gets stolen?   Today, a smartphone clones your personality into the digital world. Your phone archives all your emails and messaging communications with your family, friends, peers and colleagues; contains photos and videos of the top moments of your life; holds your favourite music and movies and zillions of other bits of personal information stored in the apps of your choice (like GPS information of your jogging paths, a vault of your passwords, access to your Facebook or Twitter profiles, bank access information, flight and hotel bookings). In the future, your phone might also be used for making payments in shops. Have you ever thought of how you would feel if you lost your smartphone or it got stolen? Nak...

  18. Lost by Design.

    Science.gov (United States)

    Ciacci, Luca; Reck, Barbara K; Nassar, N T; Graedel, T E

    2015-08-18

    In some common uses metals are lost by intent-copper in brake pads, zinc in tires, and germanium in retained catalyst applications being examples. In other common uses, metals are incorporated into products in ways for which no viable recycling approaches exist, examples include selenium in colored glass and vanadium in pigments. To determine quantitatively the scope of these "losses by design", we have assessed the major uses of 56 metals and metalloids, assigning each use to one of three categories: in-use dissipation, currently unrecyclable when discarded, or potentially recyclable when discarded. In-use dissipation affects fewer than a dozen elements (including mercury and arsenic), but the spectrum of elements dissipated increases rapidly if applications from which they are currently unrecyclable are considered. In many cases the resulting dissipation rates are higher than 50%. Among others, specialty metals (e.g., gallium, indium, and thallium) and some heavy rare earth elements are representative of modern technology, and their loss provides a measure of the degree of unsustainability in the contemporary use of materials and products. Even where uses are currently compatible with recycling technologies and approaches, end of life recycling rates are in most cases well below those that are potentially achievable. The outcomes of this research provide guidance in identifying product design approaches for reducing material losses so as to increase element recovery at end-of-life.

  19. An Analysis of Lost Sales

    Directory of Open Access Journals (Sweden)

    Jeffrey E. Jarrett

    2015-08-01

    Full Text Available The purpose of this manuscript is to shed light on problems associated with lost sales and the incurring of cost associated with lost sales. An investigation is made to determine if seasonality in sales and lost sales have effects on the efficient operations of supply chains. Optimization is always a goal of management supply chains, but cost increases due to insufficient inventory, low-quality product and the like lead to customers not returning. These are lost sales that occur for many reasons. We study a data set to determine if the ignoring of time series component also has an effect on the variation in lost sales. If so, can we measure the magnitude of the effects of seasonal variation in lost sales, and what are their consequences?

  20. The lost children.

    Science.gov (United States)

    Smith, S

    1999-03-01

    Women who have lost children to perinatal complications, are subjected to pain and grief continuously; however their agony increases on remembrance days such as birthdate, or on Mother's Day. Fathers, siblings and grandparents suffer too. Common disorders of pregnancy, such as pregnancy-induced hypertension (PIH), or the more serious pre-eclampsia, HELLP syndrome, or eclampsia, can lead to devastating effects such as miscarriage, stillbirth, or neonatal death; or at the very least, a sick infant. With many of these consequences, the loss of the dreams, hopes and plans that parents have made is imminent. The investigation of the psychosocial aspects of 'high-risk' pregnancy has never been fully addressed. However, the threat of loss, or the actual experience, may provoke the onset of a potential psychological crisis during the perinatal period. Therefore, it is important that these issues be addressed by the nurse in order to aid the development of coping mechanisms to enable women and their families to deal with what may happen. This may be done by predicting the stages of the bereavement process experienced by these women and their family members, as outlined in the Kubler-Ross model of bereavement (1969), which is indicative of many types of grief reactions. Other issues including the restriction in activity, uncertainty of pregnancy outcomes, disruption in work or career activities, financial strains, and reduced labour and birthing options, become concerns for high-risk pregnant women. The way women deal with these issues and the pathways nurses can take to help these women develop effective coping strategies, will be addressed also.

  1. Lost in a Transmedia Universe

    Directory of Open Access Journals (Sweden)

    Aaron Smith

    2011-12-01

    Full Text Available Este artigo (previamente publicado como um capítulo de minha tese analisa os mecanismos transmidiáticos de storytelling por trás da narrativa do seriado Lost, da ABC. Por ter sua narrativa sustentada em uma complexa mitologia, Lost faz um grande esforço para suplementar a narrativa de seu programa de TV através de valiosas e distintas extensões narrativas. Em um primeiro momento, eu examino como as técnicas de construção de mundo em Lost encorajam os fãs mais ávidos a “jogar” com o espaço narrativo. Eu então faço avaliações sobre as extensões que Lost oferece como opcionais, através de experiências convincentes em seus textos expandido. Ao  ser muito bem-sucedida ao balancear seus fãs mais ávidos com os casuais espectadores, Lost representa o futuro de muitos programas de televisão que se propõem a colocar os fãs em situações imersivas, usando um vasto universo transmídia, ao mesmo tempo prometendo um programa de televisão coerente em seu interior

  2. Jungmann's translation of Paradise Lost

    OpenAIRE

    Janů, Karel

    2014-01-01

    This thesis examines Josef Jungmann's translation of John Milton's Paradise Lost. Josef Jungmann was one of the leading figures of the Czech National Revival and translated Milton 's poem between the years 1800 and 1804. The thesis covers Jungmann's theoretical model of translation and presents Jungmann's motives for translation of Milton's epic poem. The paper also describes the aims Jungmann had with his translation and whether he has achieved them. The reception Jungmann's translation rece...

  3. William Paley's lost "intelligent design".

    Science.gov (United States)

    Shapiro, Adam R

    2009-01-01

    William Paley's Natural Theology has experienced a resurgence in popularity in recent decades with the continuing controversies over the teaching of evolution and the emergence of a new "intelligent design" movement. But while both the movement's supporters and detractors agree that Paley is an intellectual forefather of the present-day movement, this agreement is forged at the expense of historical accuracy. Paley's intelligent design has almost nothing in common with the present day movement and, in fact, suggests theological arguments against the type of reasoning used by the modern movement. Paley wrote in reaction to Hume and in response to the evolutionary theories of Buffon and Erasmus Darwin. In this light, the Natural Theology suggests a different reading than it is usually given. Paley's narrowly-argued theology relies upon the ability to detect the presence of "purpose" in nature without relying upon knowing what those purposes are. His empirically-argued theology leads him to a God who operates through natural law, not in its contravention, and his concern goes far beyond proving the existence of a deity to undertaking the theological project of determining the attributes and characteristics of the deity. Though not himself an evolutionist, Paley put forth a theological worldview consistent with evolution. In fact, given his arguments that the observation of great contrivance increases the testimony of nature to God's power, Paley's philosophy might be more consistent with a theistic Darwinian evolution than with special creation.

  4. Demystifying communication signal lost for network redundancy ...

    African Journals Online (AJOL)

    These studies report on the communication signal lost factors that were analyzed and supported by evidences on coverage analysis activities for Automatic Meter Reading (AMR) systems. We have categorized the influential signal lost factors into four core elements that were concluded based on our field measurement ...

  5. Hidden costs, value lost: uninsurance in America

    National Research Council Canada - National Science Library

    Committee on the Consequences of Uninsurance

    2003-01-01

    Hidden Cost, Value Lost , the fifth of a series of six books on the consequences of uninsurance in the United States, illustrates some of the economic and social losses to the country of maintaining...

  6. Lost Cause: an interactive movie project

    OpenAIRE

    Johnson, Kirsten

    2008-01-01

    One of the challenges in designing an interactive cinematic experience is to offer interactive choices which do not distract from immersion into the story. The interactive movie project, Lost Cause focuses on the life of the main character explored through the inter-related perspectives of three other characters. Lost Cause supports an immersive interactive story experience through its correlated design of an interface, narrative content and narrative structure. The movie project is examined ...

  7. Lost-sales inventory theory : A review

    NARCIS (Netherlands)

    Bijvank, Marco; Vis, Iris F. A.

    2011-01-01

    In classic inventory models it is common to assume that excess demand is backordered. However, studies analyzing customer behavior in practice show that most unfulfilled demand is lost or an alternative item/location is looked for in many retail environments. Inventory systems that include this

  8. Retail inventory management with lost sales

    NARCIS (Netherlands)

    Curseu - Stefanut, A.

    2012-01-01

    The inventory control problem of traditional store-based grocery retailers has several challenging features. Demand for products is stochastic, and is typically lost when no inventory is available on the shelves. As the consumer behavior studies reveal, only a small percentage of customers are

  9. Concern about Lost Talent: Support Document

    Science.gov (United States)

    Sikora, Joanna; Saha, Lawrence J.

    2011-01-01

    This document was produced by the authors based on their research for the report "Lost talent? The occupational ambitions and attainments of young Australians", and is an added resource for further information. The purpose of this supplement is to provide greater detail about the background of research into the topic of human talent in…

  10. "Lost in a shopping mall" -- a breach of professional ethics.

    Science.gov (United States)

    Crook, Lynn S; Dean, Martha C

    1999-01-01

    The "lost in a shopping mall" study has been cited to support claims that psychotherapists can implant memories of false autobiographical information of childhood trauma in their patients. The mall study originated in 1991 as 5 pilot experiments involving 3 children and 2 adult participants. The University of Washington Human Subjects Committee granted approval for the mall study on August 10, 1992. The preliminary results with the 5 pilot subjects were announced 4 days laters. An analysis of the mall study shows that beyond the external misrepresentions, internal scientific methodological errors cast doubt on the validity of the claims that have been attributed to the mall study within scholarly and legal arenas. The minimal involvement -- or, in some cases, negative impact -- of collegial consultation, acadmic supervision, and peer review throughout the evolution of the mall study are reviewed.

  11. Has Microfinance Lost its Moral Compass?

    OpenAIRE

    David Hulme; Mathilde Maitrot

    2014-01-01

    Abstract This paper argues that microfinance in South Asia, like mainstream finance in North America and Europe, "has lost its moral compass". Our particular concern is with microloans to vulnerable clients. Microfinance institutions (MFIs) have increasingly focussed on financial performance and have neglected their declared social mission of poverty reduction and empowerment. Loans officers in the field are under enormous pressure to achieve individual financial targets and now routinely mis...

  12. Lost lake - restoration of a Carolina bay

    Energy Technology Data Exchange (ETDEWEB)

    Hanlin, H.G.; McLendon, J.P. [Univ. of South Carolina, Aiken, SC (United States). Dept. of Biology and Geology; Wike, L.D. [Univ. of South Carolina, Aiken, SC (United States). Dept. of Biology and Geology]|[Westinghouse Savannah River Co., Aiken, SC (United States). Savannah River Technology Center; Dietsch, B.M. [Univ. of South Carolina, Aiken, SC (United States). Dept. of Biology and Geology]|[Univ. of Georgia, Aiken, SC (United States)

    1994-09-01

    Carolina bays are shallow wetland depressions found only on the Atlantic Coastal Plain. Although these isolated interstream wetlands support many types of communities, they share the common features of having a sandy margin, a fluctuating water level, an elliptical shape, and a northwest to southeast orientation. Lost Lake, an 11.3 hectare Carolina bay, was ditched and drained for agricultural production before establishment of the Savannah River Site in 1950. Later it received overflow from a seepage basin containing a variety of chemicals, primarily solvents and some heavy metals. In 1990 a plan was developed for the restoration of Lost Lake, and restoration activities were complete by mid-1991. Lost Lake is the first known project designed for the restoration and recovery of a Carolina bay. The bay was divided into eight soil treatment zones, allowing four treatments in duplicate. Each of the eight zones was planted with eight species of native wetland plants. Recolonization of the bay by amphibians and reptiles is being evaluated by using drift fences with pitfall traps and coverboard arrays in each of the treatment zones. Additional drift fences in five upland habitats were also established. Hoop turtle traps, funnel minnow traps, and dip nets were utilized for aquatic sampling. The presence of 43 species common to the region has been documented at Lost Lake. More than one-third of these species show evidence of breeding populations being established. Three species found prior to the restoration activity and a number of species common to undisturbed Carolina bays were not encountered. Colonization by additional species is anticipated as the wetland undergoes further succession.

  13. The lost art of finding our way

    CERN Document Server

    Huth, Edward John

    2013-01-01

    Long before GPS, Google Earth, and global transit, humans traveled vast distances using only environmental clues and simple instruments. John Huth asks what is lost when modern technology substitutes for our innate capacity to find our way. Encyclopedic in breadth, weaving together astronomy, meteorology, oceanography, and ethnography, The Lost Art of Finding Our Way puts us in the shoes, ships, and sleds of early navigators for whom paying close attention to the environment around them was, quite literally, a matter of life and death. Haunted by the fate of two young kayakers lost in a fogbank off Nantucket, Huth shows us how to navigate using natural phenomena—the way the Vikings used the sunstone to detect polarization of sunlight, and Arab traders learned to sail into the wind, and Pacific Islanders used underwater lightning and “read” waves to guide their explorations. Huth reminds us that we are all navigators capable of learning techniques ranging from the simplest to the most sophisticated skil...

  14. Years of life lost through Down's syndrome.

    Science.gov (United States)

    Jones, M B

    1979-10-01

    A congenital genetic condition does not act either as a cause of death or at the time of death only. Hence, years of life lost through such a conditon cannot be calculated in the same way as for a conventional cause of death. The main difference is that a cause of death acting at age x cuts off as many years of life as the dead person might otherwise have expected to live (life expectancy at age x), whereas a congenital genetic condition exposes an affected person to a different schedule of life-threatening risks from birth onwards. In the latter case, years of life lost is calculated as the difference in life expectancy at birth for affected and non-affected persons. This reasoning is worked out in algebraic form and then applied to Down's syndrome. The data base is provided by two large and recent studies, one in Massachusetts and the other in Denmark, of mortality rates among all cases of Down's syndrome, whether in an institution or not, born during a given period of years or living at a given point in time in a fixed geographical area. So calculated, years of life lost through Down's syndrome relative to the United States general population in 1970 was 53.6 years per 1000 livebirths. Prenatal mortality is also discussed.

  15. America’s Lost Innocence and Cinema

    OpenAIRE

    Patrycja Włodek

    2015-01-01

    In my paper America’s Lost Innocence I intend to focus on American cinema of the ’50s, part of ’60s, and contemporary throwbacks to those decades. The ’50s have been called “the last decade of American innocence”, “the happiest decade in America’s history – when things were going on – that everybody misses” (by Jean Baudrillard). That era symbolically ceased on 22 November 1963; however, many scholars and publicists undermine the belief in its very existence. Michael Wood calls the ’50s a tim...

  16. 21 CFR 1305.26 - Lost electronic orders.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Lost electronic orders. 1305.26 Section 1305.26... CONTROLLED SUBSTANCES Electronic Orders § 1305.26 Lost electronic orders. (a) If a purchaser determines that an unfilled electronic order has been lost before or after receipt, the purchaser must provide, to...

  17. 50 CFR 25.22 - Lost and found articles.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Lost and found articles. 25.22 Section 25.22 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR... Lost and found articles. Lost articles or money found on a national wildlife refuge are to be...

  18. Lost Talent? The Occupational Ambitions and Attainments of Young Australians

    Science.gov (United States)

    Sikora, Joanna; Saha, Lawrence J.

    2011-01-01

    Given ongoing interest in increasing productivity and participation in the workforce, understanding when talent is lost is a useful exercise. The term "lost talent" describes the underutilisation or wastage of human potential. Focusing on young people, Sikora and Saha define lost talent as occurring when students in the top 50% of…

  19. Lost Causes in and Beyond Physics

    CERN Document Server

    Streater, R F

    2007-01-01

    Lost Causes in and Beyond Physics deals with a selection of research topics mostly from theoretical physics that have been shown to be a dead-end or continue at least to be highly controversial. Nevertheless, whether it is about Bohmian mechanics, physics from Fisher information or the quantum theory of the brain, small but dedicated research communities continue to work on these issues. R.F. Streater, renowned mathematical physicist and co-author of the famous book "PCT, Spin and Statistics, and all that", in a series of essays describes the work and struggle of these research commnities, as well as the chances of any breakthrough in these areas. This book is written as both an entertainment and serious study and should be accessible to anyone with a background in theoretical physics and mathematics.

  20. Lost in the mall: misrepresentations and misunderstandings.

    Science.gov (United States)

    Loftus, Elizabeth F

    1999-01-01

    Readers of Ethics and Behavior have been treated to a misrepresentation of my research on planting false memories, to a misstatement of the actual empirical finidngs, and to a distortion of the history of the development of the idea for this line of research. The partisan essay by Crook and Dean which appears in this issue ("'Lost in a Shopping Mall' -- A Breach of Professional Ethics") is disturbing not only because of its errors, exaggerations, and omissions, but because, in some instances, the quality of the argument makes one wonder whether these were innocent mistakes or a deliberate attempt to distort my work. Some of these errors can be explained by simple lack of scientific competence. However, others are sufficiently bizarre that they cast doubt on the process that led to the acceptance of a manuscript written by an individual who has continually made her animosity toward me very publicly known (e.g., Boerner, 1996; Neimark, 1996).

  1. Dark Galaxies and Lost Baryons (IAU S244)

    Science.gov (United States)

    Davies, Jonathan I.; Disney, Michael J.

    2008-05-01

    Preface; Conference prelims; The HI that barked in the night M. J. Disney; The detection of dark galaxies in blind HI surveys J. I. Davies; Red haloes of galaxies - reservoirs of baryonic dark matter? E. Zackrisson, N. Bergvall, C. Flynn, G. Ostlin, G. Micheva and B. Baldwell; Constraints on dark and visible mass in galaxies from strong gravitational lensing S. Dye and S. Warren; Lost baryons at low redshift S. Mathur, F. Nicastro and R. Williams; Observed properties of dark matter on small spatial scales R. Wyse and G. Gilmore; The mass distribution in spiral galaxies P. Salucci; Connecting lost baryons and dark galaxies via QSO absorption lines T. Tripp; ALFALFA: HI cosmology in the local universe R. Giovanelli; The ALFALFA search for (almost) dark galaxies across the HI mass function M. Haynes; HI clouds detected towards Virgo with the Arecibo Legacy Fast ALFA Survey B. Kent; Cosmic variance in the HI mass function S. Schneider; The Arecibo Galaxy Environments Survey - potential for finding dark galaxies and results so far R. Minchin et al.; Free-floating HI clouds in the M81 group E. Brinks, F. Walter and E. Skillman; Where are the stars in dark galaxies J. Rosenberg, J. Salzer and J. Cannon; The halo by halo missing baryon problem S. McGaugh; The local void is really empty R. Tully; Voids in the local volume: a limit on appearance of a galaxy in a dark matter halo A. Tikhonov and A. Klypin; Dim baryons in the cosmic web C. Impey; A census of baryons in galaxy clusters and groups A. Gonzalez, D. Zaritsky and A. Zabludo; Statistical properties of the intercluster light from SDSS image stacking S. Zibetti; QSO strong gravitational lensing and the detection of dark halos A. Maccio; Strong gravitational lensing: bright galaxies and lost dark-matter L. Koopmans; Mapping the distribution of luminous and dark matter in strong lensing galaxies I. Ferreras, P. Saha, L. Williams and S. Burles; Tidal debris posing as dark galaxies P. Duc, F. Bournaud and E. Brinks

  2. The lost honour of Henrietta Leavitt

    Science.gov (United States)

    Del Puerto, C.

    2011-11-01

    The first scene opens with the music of Shirley Bassey. The astronomer Henrietta Swan Leavitt is writing a diary when visited by the famous CBS reporter Edward Roscoe Murrow. Henrietta is surprised that this American television channel should want to pay such a tribute to her, but she agrees to be interviewed. Annie Jump Cannon, her friend and colleague from Harvard College Observatory, accompanies her during most of the sessions. Everything goes so well that the journalist tries to touch on certain issues that Henrietta seems to want to keep secret, such as her relationship with Edward Charles Pickering, Director of the Observatory, and the reason why she failed to get the recognition for her work that she deserved.This is the argument of the play The Lost Honor of Henrietta Leavitt, a project of the Museo de la Ciencia y el Cosmos (Museum of Science and the Cosmos), run by the Organismo Autonomo de Museos y Centros of Cabildo de Tenerife (Autonomous Organism of Museums and Centres of the island government, Cabildo of Tenerife), with funding from the Spanish Foundation for Science and Technology (FECYT) and designed for the International Year of Astronomy 2009. The play, written and directed by the author, Carmen del Puerto, has been staged eight times in Tenerife and Pamplona. The poster values this experience as a resource for scientific popularization.

  3. [How much water is lost during breathing?].

    Science.gov (United States)

    Zieliński, Jakub; Przybylski, Jacek

    2012-01-01

    Arising from the Antoine equation and the ideal gas law, the volume of exhaled water has been calculated. Air temperature, humidity and minute ventilation has been taken into account. During physical exercise amount of exhaled H(2)O is linear, but not proportional to heart rate. And so at the heart rate of 140 bpm amount of exhaled water is approximately four times higher than during the rest and equals about 60-70 ml/h. The effect of external temperature and humidity on water lost via lungs was assessed as well. When temperature of inspired air and its humidity is 35°C an 75% respectively loss of water is 7 ml/h. Whereas when above parameters are changed to minus 10°C and 25% lung excretion of H(2)O increases up to 20 ml/h. The obtained results may become the basis for the assessment of osmolarity changes on the surface of the lower airways. The increase of which is recently considered as one of the factors responsible for exercise induced bronchospasm.

  4. Leopold Infeld: Hope Lost, Hope Regained

    International Nuclear Information System (INIS)

    Richmond, T.

    1999-01-01

    This lecture was delivered by the author of the book ''Konin: A Quest'', which describes the history of the Jewish community in the small town of Konin in central Poland. Unable at that time to find employment in any university in Poland, Leopold Infeld served there as headmaster of a Jewish co-educational high school between 1922 and 1924. Drawing on his own researches as well as Infeld's memoir ''Quest: The Evolution of a Scientist'', the author presents Infeld within the context of his family's social and religious background, and his ''exile'' years as a teacher in Konin, evoking a little-known period in the scientist's life. (author)

  5. America’s Lost Innocence and Cinema

    Directory of Open Access Journals (Sweden)

    Patrycja Włodek

    2015-10-01

    Full Text Available In my paper America’s Lost Innocence I intend to focus on American cinema of the ’50s, part of ’60s, and contemporary throwbacks to those decades. The ’50s have been called “the last decade of American innocence”, “the happiest decade in America’s history – when things were going on – that everybody misses” (by Jean Baudrillard. That era symbolically ceased on 22 November 1963; however, many scholars and publicists undermine the belief in its very existence. Michael Wood calls the ’50s a time of “self-deception”; therefore, the question raised is – has America ever been innocent? By concentrating on the message conveyed by mostly genre (e.g. drama, melodrama, musical, romantic comedy and mainstream movies made in the ’50s and early ’60s (e.g. A Place In the Sun, Cat on the Hot, Tin Roof, Home From the Hill, I intend to analyze the portrait of American society of that time, it’s rules and expectations towards individuals and system as a whole. In the second part of my paper I will focus on contemporary throwbacks to those times depicted mostly in movies made in the 21st century, although not exclusively (e.g. Far From Heaven, The Hours, Revolutionary Road, the TV series Mad Men [2007–], Pleasantville. Using those and other movies as examples, I intend to prove the thesis that the phenomenon of retro and contemporary retromania are not always and not by definition conservative, and can serve as a means to a critical approach towards society.

  6. Cause-specific measures of life years lost

    Directory of Open Access Journals (Sweden)

    Per Kragh Andersen

    2013-12-01

    Full Text Available Background: A new measure of the number of life years lost due to specific causes of death is introduced. Methods: This measure is based on the cumulative incidence of death, it does not require "independence" of causes, and it satisfies simple balance equations: "total number of life years lost = sum of cause-specific life years lost", and "total number of life years lost before age x + temporary life expectancy between birth and age x = x". Results: The measure is contrasted to alternatives suggested in the demographic literature and allmethods are illustrated using Danish and Russian multiple decrement life-tables.

  7. Considering lost sale in inventory routing problems for perishable goods

    DEFF Research Database (Denmark)

    Mirzaei, Samira; Seifi, Abbas

    2015-01-01

    , the average optimality gaps are less than 10.9% and 13.4% using linear and exponential lost sale functions, respectively. Furthermore, we show that the optimality gaps found by CPLEX grow exponentially with the problem size while those obtained by the proposed meta-heuristic algorithm increase linearly....... is considered as lost sale. The proposed model balances the transportation cost, the cost of inventory holding and lost sale. In addition to the usual inventory routing constraints, we consider the cost of lost sale as a linear or an exponential function of the inventory age. The proposed model is solved...

  8. Carbon debt - Lost in the forest?

    DEFF Research Database (Denmark)

    Bentsen, Niclas Scott

    2014-01-01

    The concept of ‘carbon debt’ and carbon payback time with reference to bioenergy and biofuels was probably launched by anarticle in Science in 2008. The concept is increasingly seen as an indicator of the sustainability of bioenergy supply chains.Particularly for forest bioenergy supply chains...... the time lapse between harvest and regrowth may be a signifi cant factor for themodeled carbon debt. A meta-analysis of more than 250 model scenarios was conducted to evaluate the factors and assumptionsdetermining carbon debts and payback time of forest bioenergy supply chains. Factors such as spatial...... and temporal scale, biome,origin of the wood resource, which fossil fuels are displaced, forest history, baseline scenario, accounting principle, and databackground were included in the analysis. This paper discusses the evolution of the carbon debt concept, how different factorsand assumptions infl uence...

  9. 36 CFR 327.16 - Lost and found articles.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Lost and found articles. 327... CHIEF OF ENGINEERS § 327.16 Lost and found articles. All articles found shall be deposited by the finder at the Manager's office or with a ranger. All such articles shall be disposed of in accordance with...

  10. Lost circulation technology workshop, October 9-10, 1984

    Energy Technology Data Exchange (ETDEWEB)

    Caskey, B.C. (ed.)

    1985-03-01

    This report summarizes the presentations and discussions of a workshop on lost circulation technology. The workshop identified and defined lost circulation problem areas in field operations, materials, mud effects, and standards. Problem solution needs were also categorized as requiring analytical evaluation and procedure, instrument, and material development.

  11. 42 CFR 102.32 - Benefits for lost employment income.

    Science.gov (United States)

    2010-10-01

    ... 102.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX... pay for lost employment income or to provide disability or retirement benefits to the requester. As provided in § 102.84, the Secretary retains the right to recover benefits for lost employment income paid...

  12. 32 CFR 635.31 - Lost, abandoned, or unclaimed property.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Lost, abandoned, or unclaimed property. 635.31 Section 635.31 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.31 Lost, abandoned, or unclaimed property. This is...

  13. SYNTHETIC AGB EVOLUTION .1. A NEW MODEL

    NARCIS (Netherlands)

    GROENEWEGEN, MAT; DEJONG, T

    We have constructed a model to calculate in a synthetic way the evolution of stars on the asymptotic giant branch (AGB). The evolution is started at the first thermal pulse (TP) and is terminated when the envelope mass has been lost due to mass loss or when the core mass reaches the Chandrasekhar

  14. In search for the lost identity: a post-modern look at Lost

    Directory of Open Access Journals (Sweden)

    Lucas Gomes Thimóteo

    2012-11-01

    Full Text Available This study discusses the American television show Lost, in order to establish a relationship among technological advances, media and configuration of the contemporary subject, based on phenomenon of convergence as a possibility that integrates and modifies the subject. The analysis focuses on two moments. The first characterizes its structure as a transmedia narrative, resulting in a format called convergence culture, that emerges nowadays with the mass of content and media that surround us. In the second moment, some elements are observed in the series that are correlated to themes addressed by postmodernity. Thus we intend to demonstrate how the narrative presented portrays situations of reality in fiction, providing an identification of the post-modern subject with the show.

  15. Paradise Lost Dressed in the Costume of History: John Martin’s Rendition of Paradise Lost

    Directory of Open Access Journals (Sweden)

    Laleh Atashi

    2011-01-01

    Full Text Available The story of the loss of paradise has been read and interpreted in different ages. Commentary on Milton's Paradise Lost is not limited to verbal texts; painters and illustrators have contributed greatly to the poem by presenting their own time-bound readings and interpretations of the poem through their illustrations that are far beyond mere decorations. John Martin, in the aftermath of the Industrial Revolution, deletes the Father and the Son from his illustrations. Only angels such as Raphael are the representations of deity and are as powerless and tiny as Adam and Eve. Adam and Eve, after the Fall seem as small, powerless and as subjugated to the natural surrounding as they were before the Fall. Satan is the only powerful figure in his elegant palace. Through a new historical outlook, the researchers aim at exposing the workings of ideology and dominant discourses that informed John Martin's pictorial reading of Milton's poem in the early 19th century

  16. Idiopathic focal epilepsies: the "lost tribe".

    Science.gov (United States)

    Pal, Deb K; Ferrie, Colin; Addis, Laura; Akiyama, Tomoyuki; Capovilla, Giuseppe; Caraballo, Roberto; de Saint-Martin, Anne; Fejerman, Natalio; Guerrini, Renzo; Hamandi, Khalid; Helbig, Ingo; Ioannides, Andreas A; Kobayashi, Katsuhiro; Lal, Dennis; Lesca, Gaetan; Muhle, Hiltrud; Neubauer, Bernd A; Pisano, Tiziana; Rudolf, Gabrielle; Seegmuller, Caroline; Shibata, Takashi; Smith, Anna; Striano, Pasquale; Strug, Lisa J; Szepetowski, Pierre; Valeta, Thalia; Yoshinaga, Harumi; Koutroumanidis, Michalis

    2016-09-01

    The term idiopathic focal epilepsies of childhood (IFE) is not formally recognised by the ILAE in its 2010 revision (Berg et al., 2010), nor are its members and boundaries precisely delineated. The IFEs are amongst the most commonly encountered epilepsy syndromes affecting children. They are fascinating disorders that hold many "treats" for both clinicians and researchers. For example, the IFEs pose many of the most interesting questions central to epileptology: how are functional brain networks involved in the manifestation of epilepsy? What are the shared mechanisms of comorbidity between epilepsy and neurodevelopmental disorders? How do focal EEG discharges impact cognitive functioning? What explains the age-related expression of these syndromes? Why are EEG discharges and seizures so tightly locked to slow-wave sleep? In the last few decades, the clinical symptomatology and the respective courses of many IFEs have been described, although they are still not widely appreciated beyond the specialist community. Most neurologists would recognise the core syndromes of IFE to comprise: benign epilepsy of childhood with centro-temporal spikes or Rolandic epilepsy (BECTS/RE); Panayiotopoulos syndrome; and the idiopathic occipital epilepsies (Gastaut and photosensitive types). The Landau-Kleffner syndrome and the related (idiopathic) epilepsy with continuous spikes and waves in sleep (CSWS or ESES) are also often included, both as a consequence of the shared morphology of the interictal discharges and their potential evolution from core syndromes, for example, CSWS from BECTS. Atypical benign focal epilepsy of childhood also has shared electro-clinical features warranting inclusion. In addition, a number of less well-defined syndromes of IFE have been proposed, including benign childhood seizures with affective symptoms, benign childhood epilepsy with parietal spikes, benign childhood seizures with frontal or midline spikes, and benign focal seizures of adolescence. The

  17. [Work days lost due to health problems in industry].

    Science.gov (United States)

    Yano, Sylvia Regina Trindade; Santana, Vilma Sousa

    2012-05-01

    This cross-sectional study estimated the prevalence of work days lost due to health problems and associated factors among industrial workers. The study population was a simple random cluster sample of 3,403 workers from 16 to 65 years of age in the city of Salvador, Bahia State, Brazil. Data were collected with individual home interviews. Among industrial workers, one-year prevalence of work days lost to health problems was 12.5%, of which 5.5% were directly work-related and 4.1% aggravated by work. There were no statistically significant differences when compared to other worker categories. Self-perceived workplace hazards, history of work-related injury, and poor self-rated health were associated with work days lost due to work-related injuries/diseases. The findings showed that work days lost are common among both industrial and non-industrial workers, thereby affecting productivity and requiring prevention programs.

  18. Ship Track for Lost City 2005 - Office of Ocean Exploration

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Ship track of the NOAA ship Ronald H. Brown during the "Lost City 2005" expedition sponsored by the National Oceanic and Atmospheric Administration (NOAA) Office of...

  19. Measurement of water lost from heated geologic salt

    International Nuclear Information System (INIS)

    Hohlfelder, J.J.

    1979-07-01

    This report describes three methods used to measure the rate at which water is lost from heated geologic salt. The three methods were employed in each of a series of proof tests which were performed to evaluate instrumentation designed to measure the water-loss rate. It was found that the water lost from heated, 1-kg salt specimens which were measured according to these three methods was consistent to within an average 9 percent

  20. Lost in Location:- on how (not) to situate aliens

    OpenAIRE

    Hansen, Lone Koefoed

    2009-01-01

    Udgivelsesdato: June The article investigates how users of personal satellite navigation devices (often referred to as sat-nav) are sometimes lost and led astray and argues that the satnav's aim to remove every insecurity about the correct route seems to remove the individual's conscious perception of the space traversed. While becoming destination aware, the individual loses her location awareness. The article proposes that the reason people get lost when using sat-nav is due to a wrong l...

  1. Net lost revenue from DSM: State policies that work

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, L.W.

    1995-07-01

    A key utility regulatory reform undertaken since 1989 allows utilities to recover the lost revenue incurred through successful operation of demand-side management (DSM) programs. Net lost revenue adjustment (NLRA) mechanisms are states preferred approach to lost revenue recovery from DSM programs. This paper examines the experiences states and utilities are having with the NLRA approach. The paper has three objectives: (1) determine whether NLRA is a feasible and effective approach to the lost-revenue disincentive for utility DSM programs, (2) identify the conditions linked to effective implementation of NLRA mechanisms and assess whether NLRA has changed utility investment behavior, and (3) suggest improvements to NLRA mechanisms. Contrary to the concerns raised by some industry analysts, our results indicate NLRA is a feasible approach. Seven of the ten states we studied report no substantial problems with their approach. We observe several conditions linked to effective NLRA implementation. Observed changes in utility investment behavior occur after implementation of DSM rate reforms, which include deployment of NLRA mechanisms. Utilities in states with lost revenue recovery invest more than twice as much in DSM as do utilities in other states.

  2. Years of life lost due to external radiation exposure

    Directory of Open Access Journals (Sweden)

    Raičević Jagoš J.

    2004-01-01

    Full Text Available In this paper a new approach for calculation of the years of life lost per excess death due to stochastic health effects is applied to external exposure pathways. The short-term external exposures are due to the passage of radioactive cloud and due to the skin and clothes contamination. The long-term external exposure is the one from the radioactive material deposited on the ground (groundshine. Three nuclides, 131I, 137Cs, and 239Pu, and with the extremely wide range of half-life are considered in order to examine their possible influence on the calculated values of years of life lost. For each of these nuclides, the number of years of life lost has been found as a decreasing function of the age at the expo sure and presented graphically in this paper. For protracted exposures, the fully averaged number of years of life lost is negative correlated with the nuclide’s half-life. On the other hand, the short-term external exposures do not depend on the nuclide’s half-life. In addition, a weak years of life lost dependence of the dose has been commented.

  3. A Joint Replenishment Inventory Model with Lost Sales

    Science.gov (United States)

    Devy, N. L.; Ai, T. J.; Astanti, R. D.

    2018-04-01

    This paper deals with two items joint replenishment inventory problem, in which the demand of each items are constant and deterministic. Inventory replenishment of items is conducted periodically every T time intervals. Among of these replenishments, joint replenishment of both items is possible. It is defined that item i is replenished every ZiT time intervals. Replenishment of items are instantaneous. All of shortages are considered as lost sales. The maximum allowance for lost sales of item i is Si. Mathematical model is formulated in order to determining the basic time cycle T, replenishment multiplier Zi , and maximum lost sales Si in order to minimize the total cost per unit time. A solution methodology is proposed for solve the model and a numerical example is provided for demonstrating the effectiveness of the proposed methodology.

  4. Preventing customer defection and stimulating return of the lost customers

    Directory of Open Access Journals (Sweden)

    Senić Radoslav

    2013-01-01

    Full Text Available Customers represent company's most valuable asset. Company can assure its survival, further growth and development by retaining existing, attracting new and returning lost customers. Retaining existing, loyal customers is the most profitable business activity, attracting new ones is the most expensive, while returning lost and frequently forgotten customers is a type of business activity that still generates modest interest among researchers and practitioners. So far, marketing strategies have been mainly directed towards the first two categories of customers. The objective of this paper is dedicated to customer defection and returning lost customers. Paper discusses customer relationship life-cycle and the significance of managing customer return within it, types of customer defections, the process of managing return, as well as, the reasons that led to customer defection.

  5. MILTON’S PARADISE LOST AND A POSTCOLONIAL FALL

    OpenAIRE

    LUIZ FERNANDO FERREIRA DE SÁ

    2006-01-01

    In John Milton’s Paradise Lost epic and empire are dissociated. Contrary to many misreadings, this all-important work of the English Renaissance intersects postcolonial thinking in a number of ways. By using Gayatri Spivak’s circuit of postcolonial theory and practice, this paper enacts a counterpointal (mis)reading of Milton’s text: Paradise Lost may at last free its (post-)colonial (dis)content. Since every reading is a misreading, my (mis)reading of Milton’s paradis...

  6. 32 CFR 310.50 - Lost, stolen, or compromised information.

    Science.gov (United States)

    2010-07-01

    ... Official for Privacy within 24 hours of discovering that a breach of personally identifiable information... Privacy Office of the breach within 48 hours upon being notified that a loss, theft, or compromise has... (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Privacy Act Violations § 310.50 Lost, stolen, or compromised...

  7. Lost in localization: A solution with neuroinformatics 2.0?

    DEFF Research Database (Denmark)

    Nielsen, Finn Årup

    2009-01-01

    The commentary by Derrfuss and Mar (Derrfuss, J., Mar, R.A., 2009. Lost in localization: The need for a universal coordinate database. NeuroImage, doi:10.1016/j.neuroimage.2009.01.053.) discusses some of the limitations of the present databases and calls for a universal coordinate database. Here I...

  8. Lost but Not Forgotten: Finding Pages on the Unarchived Web

    NARCIS (Netherlands)

    Huurdeman, H.C.; Kamps, J.; Samar, T.; de Vries, A.P.; Ben-David, A.; Rogers, R.A.

    2015-01-01

    Web archives attempt to preserve the fast changing web, yet they will always be incomplete. Due to restrictions in crawling depth, crawling frequency, and restrictive selection policies, large parts of the Web are unarchived and, therefore, lost to posterity. In this paper, we propose an approach to

  9. Lost but not forgotten: finding pages on the unarchived web

    NARCIS (Netherlands)

    H.C. Huurdeman; J. Kamps; T. Samar (Thaer); A.P. de Vries (Arjen); A. Ben-David; R.A. Rogers (Richard)

    2015-01-01

    htmlabstractWeb archives attempt to preserve the fast changing web, yet they will always be incomplete. Due to restrictions in crawling depth, crawling frequency, and restrictive selection policies, large parts of the Web are unarchived and, therefore, lost to posterity. In this paper, we propose an

  10. Transforming Dance History: The Lost History of Rehearsals.

    Science.gov (United States)

    Hodes, Stuart

    1989-01-01

    Explains that an important aspect of dance history is lost by not recording dance rehearsals. Argues that recording rehearsals can reveal the creative process and illuminate the environment that engendered this art form. Concludes that a transformed dance history will influence curriculum development. (GG)

  11. Paradise Lost: Introducing Students to Climate Change through Story

    Science.gov (United States)

    Bennon, Brady

    2013-01-01

    "This country has been the basis of my being. And when it's no longer there, you know, it's unthinkable." Ueantabo Mackenzie's haunting words in the PBS NOW documentary "Paradise Lost" shook the author. He knew he wanted to teach a unit on global warming, especially after participating in the Portland-area Rethinking Schools…

  12. Notes from the Lost Property Department. Bridget Pitt. Cape Town ...

    African Journals Online (AJOL)

    as a loss of motor-skills and memory, and changes in behaviour. Bridget Pitt's Notes from the Lost Property Department (2015) is primarily concerned with the ways in which these invisible wounds cause dis- junctions in personal identity and fissures in relationships. ... together her cracked sense of self, all the time keeping ...

  13. Reasserting the primacy of human needs to reclaim the 'lost half' of sustainable development.

    Science.gov (United States)

    Everard, Mark; Longhurst, James W S

    2018-04-15

    The concept of sustainable development evolved from growing awareness of the interdependence of social and economic progress with the limits of the supporting natural environment, becoming progressively integrated into global agreements and transposition into local regulatory and implementation frameworks. We argue that transposition of the concept into regulation and supporting tools reduced the focus to minimal environmental and social standards, perceived as imposing constraints rather than opportunities for innovation to meet human needs. The aspirational 'half' of the concept of sustainable development specifically addressing human needs was thus lost in transposing high ideals into regulatory instruments. The Sustainable Development Goals (SDGs) restore focus on interlinked human needs, stimulating innovation of products and processes to satisfy them. Through three case studies - PVC water pipes, river quality management in England, and UK local air quality management - we explore the current operationalisation of the concept in diverse settings, using the SDG framework to highlight the broader societal purposes central to sustainable development. Partnerships involving civil society support evolution of regulatory instruments and their implementation, optimising social and ecological benefits thereby serving more human needs. Restoring the visionary 'lost half' of sustainable development - meeting human needs in sustainable ways - creates incentives for innovation and partnership; an innovation framework rather than a perceived constraint. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Mobile Applications Improve Quality of Life on Citizens with Disorientation: The 'NeverLost App' Paradigm.

    Science.gov (United States)

    Fotiou, Sotirios; Vlamos, Panayiotis

    2017-01-01

    Mobile technology has been evolved as an important tool in healthcare. Mobile applications are being designed in order to assist patients in their everyday life and also to play a vital role on the improvement of their everyday activities and quality of life. Meanwhile students use advanced techniques in order to design and implement high quality applications that aim to introduce them to the advantages of the mobile technology. In this paper we present the steps for the creation of the application NeverLost that was inspired, designed, created and tested by students of the Secondary Education. NeverLost is an Android application that helps individuals (mainly children) with disabilities, as well as older patients with lack of orientation manage their day-to-day activities. A research of the general benefits that students using this app is presented, as well as their future proposals for the evolution of the app in other aspects of healthcare and quality of life of senior citizens or patients with neurodegenerative diseases.

  15. 28 CFR 301.204 - Continuation of lost-time wages.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Continuation of lost-time wages. 301.204... ACCIDENT COMPENSATION Lost-Time Wages § 301.204 Continuation of lost-time wages. (a) Once approved, the inmate shall receive lost-time wages until the inmate: (1) Is released; (2) Is transferred to another...

  16. 28 CFR 301.203 - Payment of lost-time wages.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Payment of lost-time wages. 301.203... ACCIDENT COMPENSATION Lost-Time Wages § 301.203 Payment of lost-time wages. (a) An inmate worker may receive lost-time wages for the number of regular work hours absent from work due to injury sustained in...

  17. Lignite zone as an indicator to lost circulation belt: a case study of ...

    African Journals Online (AJOL)

    Eighteen (18) water boreholes were studied for lost circulation. When locations of the boreholes associated with lost circulation were plotted on the map of Anambra State a lost circulation belt was observed around the River Niger – Onitsha – Oba – Nnewi axis. Lost circulation intervals range between 20-50m and 75-90m ...

  18. MILTON’S PARADISE LOST AND A POSTCOLONIAL FALL

    Directory of Open Access Journals (Sweden)

    LUIZ FERNANDO FERREIRA DE SÁ

    2006-01-01

    Full Text Available In John Milton’s Paradise Lost epic and empire are dissociated. Contrary to many misreadings, this all-important work of the English Renaissance intersects postcolonial thinking in a number of ways. By using Gayatri Spivak’s circuit of postcolonial theory and practice, this paper enacts a counterpointal (misreading of Milton’s text: Paradise Lost may at last free its (post-colonial (discontent. Since every reading is a misreading, my (misreading of Milton’s paradise is amo(vement of resistance against and intervention in a so-called grand narrative of power (Milton’s epic with a view to proposing a postcolonial conversation with this text.

  19. Net lost revenue adjustment (NLRA) mechanisms for utility DSM programs

    International Nuclear Information System (INIS)

    Baxter, L.W.

    1995-01-01

    We examine the experiences that states and utilities are having with the NLRA approach. Contrary to concerns raised by some industry analysts, our results indicate the NLRA is a feasible approach to the lost-revenue disincentive. Seven of the 10 states we studied report no substantial problems with their approach. We observe several conditions linked to effective NLRA implementation and, for those states reporting problems, conditions linked to implementation difficulties. Finally, observed changes in utility-investment behavior occur after implementation of DSM rate reforms, which include deployment of NLRA mechanisms. We find that utilities in states with lost revenue recovery invest more than twice as much in DSM as do utilities in other states. (Author)

  20. Device for preventing coolant in a reactor from being lost

    International Nuclear Information System (INIS)

    Maruyama, Hiromi; Matsumoto, Tomoyuki.

    1975-01-01

    Object: To prevent all of coolant from being lost from the core at the time of failure in rupture of pipe in a recirculation system to cool the core with the coolant remained within the reactor. Structure: A valve, which will be closed when a water level of the coolant within the core is in a level less than a predetermined level, is provided on a recirculating water outlet nozzle in a pressure vessel to thereby prevent the coolant from being lost when the pipe is broken, thus cooling the core by means of reduced-pressure boiling of coolant remained within the core and boiling due to heat, and restraining core reactivity by means of void produced at that time. (Kamimura, M.)

  1. Is Ecotourism Just Another Story of Paradise Lost?

    OpenAIRE

    English, Brian J.

    2017-01-01

    This paper uses Milton’s epic Paradise Lost as a metaphor to highlight the pitfalls of the label “ecotourism”. Critics of ecotourism view the label as a misnomer and an advertising ploy. Therefore, in order to provide a balanced perspective of ecotourism, this paper will review the definition of ecotourism, discuss the challenges of implementing successful ecotourism projects and provide some examples of ecotourism-gone-wrong. Since seeking economic benefits of increased tourism is contradict...

  2. DIGITAL MARKETING FOR FOREIGN MARKETS. CASE: LOST IN KAJAANI

    OpenAIRE

    Akhmetyanova, Yulia

    2016-01-01

    Different marketing researches report that participation in adventure races had grown over the last 2-3 years. However, adventure races have received relatively little attention in academic literature. The focus of existing studies in this field tends to be on accidents or medical issues. At the same time social media networks have become popular. The purpose of this thesis was to describe how increased social media activity would affect awareness of the Lost in Kajaani (LiK) adventure race. ...

  3. Trade finance and Latin America's lost decade: The forgotten link

    OpenAIRE

    Alvarez, Sebastian; Flores Zendejas, Juan

    2014-01-01

    The Great recession has brought back to foreground the link between trade credit international trade and economic growth. Scholars have recently found that the effects of the fall in trade finance are strong and accurately explain the recent fall in international trade. We argue that the lost decade that followed Latin America's debt crisis is a useful comparative benchmark to recognize the scope of impact on international trade stemming from a sharp decline in trade finance. The years that f...

  4. Mental illness and lost income among adult South Africans.

    Science.gov (United States)

    Lund, Crick; Myer, Landon; Stein, Dan J; Williams, David R; Flisher, Alan J

    2013-05-01

    Little is known regarding the links between mental disorder and lost income in low- and middle-income countries. The purpose of this study was to investigate the association between mental disorder and lost income in the first nationally representative psychiatric epidemiology survey in South Africa. A probability sample of South African adults was administered the World Health Organization Composite International Diagnostic Interview schedule to assess the presence of mental disorders as defined in the Diagnostic and Statistical Manual of Mental Disorders, version IV. The presence of severe depression or anxiety disorders was associated with a significant reduction in earnings in the previous 12 months among both employed and unemployed South African adults (p = 0.0043). In simulations of costs to individuals, the mean estimated lost income associated with severe depression and anxiety disorders was $4,798 per adult per year, after adjustment for age, gender, substance abuse, education, marital status, and household size. Projections of total annual cost to South Africans living with these disorders in lost earnings, extrapolated from the sample, were $3.6 billion. These data indicate either that mental illness has a major economic impact, through the effect of disability and stigma on earnings, or that people in lower income groups are at increased risk of mental illness. The indirect costs of severe depression and anxiety disorders stand in stark contrast with the direct costs of treatment in South Africa, as illustrated by annual government spending on mental health services, amounting to an estimated $59 million for adults. The findings of this study support the economic argument for investing in mental health care as a means of mitigating indirect costs of mental illness.

  5. Life years lost among patients with a given disease

    DEFF Research Database (Denmark)

    Andersen, Per Kragh

    2017-01-01

    A number of suggested measures of life years lost among patients with a given disease are reviewed, and some new ones are proposed. The methods are all phrased in the framework of a (Markov or non-Markov) illness-death model in combination with a population life table. The methods are illustrated...... using data on Danish male patients with bipolar disorder, and some recommendations are given. Copyright © 2017 John Wiley & Sons, Ltd....

  6. Restoration of lost connectivity of partitioned wireless sensor networks

    Directory of Open Access Journals (Sweden)

    Virender Ranga

    2016-05-01

    Full Text Available The lost connectivity due to failure of large scale nodes plays major role to degrade the system performance by generating unnecessary overhead or sometimes totally collapse the active network. There are many issues and challenges to restore the lost connectivity in an unattended scenario, i.e. how many recovery nodes will be sufficient and on which locations these recovery nodes have to be placed. A very few centralized and distributed approaches have been proposed till now. The centralized approaches are good for a scenario where information about the disjoint network, i.e. number of disjoint segments and their locations are well known in advance. However, for a scenario where such information is unknown due to the unattended harsh environment, a distributed approach is a better solution to restore the partitioned network. In this paper, we have proposed and implemented a semi-distributed approach called Relay node Placement using Fermat Point (RPFP. The proposed approach is capable of restoring lost connectivity with small number of recovery relay nodes and it works for any number of disjoint segments. The simulation experiment results show effectiveness of our approach as compared to existing benchmark approaches.

  7. The Living Donor Lost Wages Trial: Study Rationale and Protocol.

    Science.gov (United States)

    Rodrigue, James R; Fleishman, Aaron; Carroll, Michaela; Evenson, Amy R; Pavlakis, Martha; Mandelbrot, Didier A; Baliga, Prabhakar; Howard, David H; Schold, Jesse D

    2018-03-01

    This paper describes the background, rationale, and design of an NIH-funded, single-center study to test the impact of offering reimbursement for donor lost wages incurred during the post-nephrectomy recovery period on the live donor kidney transplant (LDKT) rate in newly evaluated kidney transplant candidates, to examine whether offering reimbursement for donor lost wages reduces racial disparity in LDKT rates, and to determine whether higher reimbursement amounts lead to higher LDKT rates. LDKT is the optimal treatment for renal failure. However, living kidney donation has declined in the past decade, particularly among men, younger adults, blacks, and low-income adults. There is evidence that donation-related costs may deter both transplant candidates and potential donors from considering LDKT. Lost wages is a major source of financial loss for some living donors and, unlike travel and lodging expenses, is not reimbursed by financial assistance programs. The study addresses the transplant community's call to reduce the financial burden of living donation and examine its impact on LDKT rates. Findings have the potential to influence policy, clinical practice, LDKT access, and income-related and racial disparities in LDKT and living donation.

  8. Development of environmental friendly lost circulation material from banana peel

    Science.gov (United States)

    Sauki, Arina; Hasan, Nur â.€˜Izzati; Naimi, Fardelen Binti Md; Othman, Nur Hidayati

    2017-12-01

    Loss of expensive mud could lead to major financial problem in executing a drilling project and is one of the biggest problems that need to be tackled during drilling. Synthetic Based Mud (SBM) is the most stable state of the art drilling mud used in current drilling technologies. However, the problem with lost circulation is still inevitable. The focus of this project is to develop a new potential waste material from banana peel in order to combat lost circulation in SBM. Standard industrial Lost Circulation Material (LCM) is used to compare the performance of banana peel as LCM in SBM. The effects of different sizing of banana peels (600 micron, 300 micron and 100 micron) were studied on the rheological and filtration properties of SBM and the bridging performance of banana peel as LCM additive. The tests were conducted using viscometer, HTHP filter press and sand bed tester. Thermal analysis of banana peel was also studied using TGA. According to the results obtained, 300 and 100 micron size of banana peel LCM exhibited an improved bridging performance by 65% as compared to industrial LCM. However, banana peel LCM with the size of 600 micron failed to act as LCM due to the total invasion of mud into the sand bed.

  9. Restoration of Lost Lake, recovery of an impacted Carolina Bay

    International Nuclear Information System (INIS)

    Wike, L.D.; Gladden, J.B.; Mackey, H.E. Jr.; Rogers, V.A.

    1995-01-01

    Lost Lake is one of approximately 200 Carolina bays found on the Savannah River Site (SRS). Until 1984 Lost Lake was contaminated by heavy metals and solvents overflowing from a nearby settling basin. Up to 12 inches of surface soil and all vegetation was removed from the bay as part of a RCRA removal action. A plan for restoration was initiated in 1989 and implemented in 1990 and 1991. Extensive planning led to defined objectives, strategies, treatments, and monitoring programs allowing successful restoration of Lost Lake. The primary goal of the project was to restore the wetland ecosystem after a hazardous waste clean up operation. An additional goal was to study the progress of the project and the success of the restoration activity. Several strategy considerations were necessary in the restoration plan. The removal of existing organic soils had to have compensation, a treatment scheme for planting and the extent of manipulation of the substrate had to be considered, monitoring decisions had to be made, and the decision whether or not to actively control the hydrology of the restored system

  10. Earthworms lost from pesticides application in potato crops

    Science.gov (United States)

    Garcia-Santos, Glenda; Forrer, Karin; Binder, Claudia R.

    2010-05-01

    Bioturbation from earthworm's activity contributes to soil creep and soil carbon dynamics, and provide enough aeration conditions for agricultural practices all over the world. In developing countries where there is a long term misuse of pesticides for agricultural purposes, lost of these benefits from earthworms activity might already yielded negative effects in the current crop production. Little research has been performed on earthworms avoidance to pesticides in developing countries located in the tropics. Furthermore, the complete avoidance reaction (from attraction to 100% avoidance) from earthworms to most of the pesticides used in potato cultivation in developing countries like Colombia is incomplete as yet. Hence the aim of this study is to assess the lost of earthworm on the soils caused by different concentrations of pesticides and associated agricultural impacts caused by a lost in the soil bioturbation. As a first stage, we have studied earthworm's avoidance to pesticide concentration in a potato agricultural area located in Colombia. Local cultivated Eisenia fetida were exposed to four of the most frequent applied active ingredients in potato crops i.e. carbofuran, mancozeb, methamidophos and chlorpyriphos. Adult earthworm toxicity experiments were carried out in two soils, untreated grasslands under standard (ISO guidelines) and undisturbed conditions, and exposed to six different concentrations of the active ingredients. The results of the avoidance reaction on the standard soils were significant for carbofuran, mancoceb and chlorpyrifos. For each of the three active ingredients, we found i) overuse of pesticide, ii) applied dose of carbofuran, mancoceb and chlorpyrifos by the farmers potentially caused 20%, 11% and 9% of earthworms avoidance on the cultivated soils, respectively.

  11. Remittances in the Republic of Moldova:Lost opportunities

    Directory of Open Access Journals (Sweden)

    Marcel CHISTRUGA

    2011-06-01

    Full Text Available The article covers the problem of the relationship between remittances and economic growth as well as the use of remittances for productive investment in order to contribute to long-run development. Also, there are given some stylized facts of remittances in the Republic of Moldova and their impact over the national economy. Because of its business and investment climate, because of its financial system and macroeconomic policies that were conducted, Moldova has lost almost all opportunities to benefit from remittances.

  12. Years of life lost due to infectious diseases in Poland

    Science.gov (United States)

    Bryla, Marek; Dziankowska-Zaborszczyk, Elzbieta; Bryla, Pawel; Pikala, Malgorzata

    2017-01-01

    Purpose An evaluation of mortality due to infectious diseases in Poland in 1999–2012 and an analysis of standard expected years of life lost due to the above diseases. Methods The study material included a database created on the basis of 5,219,205 death certificates of Polish inhabitants, gathered between 1999 and 2012 and provided by the Central Statistical Office. Crude Death Rates (CDR), Standardized Death Rates (SDR) and Standard Expected Years of Life Lost (SEYLL) due to infectious and parasitic diseases were also evaluated in the study period as well as Standard Expected Years of Life Lost per living person (SEYLLp) and Standard Expected Years of Life Lost per dead person (SEYLLd). Time trends were evaluated with the application of joinpoint models and an annual percentage change in their values. Results Death certificates report that 38,261 people died due to infectious diseases in Poland in the period 1999–2012, which made up 0.73% of the total number of deaths. SDR caused by these diseases decreased, particularly in the male group: Annual Percentage Change (APC = -1.05; 95% CI:-2.0 to -0.2; p<0.05). The most positive trends were observed in mortality caused by tuberculosis (A15-A19) (APC = -5.40; 95% CI:-6.3 to -4.5; p<0.05) and also meningitis, encephalitis, myelitis and encephalomyelitis (G03-G04) (APC = -3.42; 95% CI:-4.7 to -2.1; p<0.05). The most negative mortality trends were observed for intestinal infectious diseases (A00-A09) Annual Average Percentage Change (AAPC = 7.3; 95% CI:3.1 to 11.7; p<0.05). SDR substantially decreased in the first half of the study period, but then significantly increased in the second half. Infectious and parasitic diseases contributed to a loss of around 37,000 standard expected years of life in 1999 and more than 28,000 in 2012. During the study period, the SEYLLp index decreased from 9.59 to 7.39 per 10,000 population and the SEYLLd index decreased from 14.26 to 10.34 years (AAPC = 2.3; 95% CI:-2,9 to -1.7; p<0

  13. The experiences of mothers who lost a baby during pregnancy

    Directory of Open Access Journals (Sweden)

    L Modiba

    2007-11-01

    Full Text Available The purpose of this study was to explore and describe the experiences of mothers who lost a baby during pregnancy and care given by doctors and midwives during this period. Opsomming Die doel van die studie was om die ervaring van moeders met betrekking tot die dood van ‘n baba tydens swangerskap te verken en te beskryf, asook die versorging wat hulle van vroedvroue en dokters gedurende die periode ontvang het. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

  14. A Serpentinite-Hosted Ecosystem: The Lost City Hydrothermal Field

    Science.gov (United States)

    Kelley, Deborah S.; Karson, Jeffrey A.; Früh-Green, Gretchen L.; Yoerger, Dana R.; Shank, Timothy M.; Butterfield, David A.; Hayes, John M.; Schrenk, Matthew O.; Olson, Eric J.; Proskurowski, Giora; Jakuba, Mike; Bradley, Al; Larson, Ben; Ludwig, Kristin; Glickson, Deborah; Buckman, Kate; Bradley, Alexander S.; Brazelton, William J.; Roe, Kevin; Elend, Mitch J.; Delacour, Adélie; Bernasconi, Stefano M.; Lilley, Marvin D.; Baross, John A.; Summons, Roger E.; Sylva, Sean P.

    2005-03-01

    The serpentinite-hosted Lost City hydrothermal field is a remarkable submarine ecosystem in which geological, chemical, and biological processes are intimately interlinked. Reactions between seawater and upper mantle peridotite produce methane- and hydrogen-rich fluids, with temperatures ranging from A low diversity of microorganisms related to methane-cycling Archaea thrive in the warm porous interiors of the edifices. Macrofaunal communities show a degree of species diversity at least as high as that of black smoker vent sites along the Mid-Atlantic Ridge, but they lack the high biomasses of chemosynthetic organisms that are typical of volcanically driven systems.

  15. The Psychopaths in Caroline Roberts’ Novel the Lost Girl

    OpenAIRE

    Tarigan, Mia Pratiwi

    2015-01-01

    The Lost Girl novel is a true story that tells about the author, Caroline Roberts’ experiences when she accepted a job at 25 Cromwell Street, the infamous address of Fred and Rose West, she was only 16. She realized that there was something very malevolent about the couple, so she left their employment soon after, glad to be rid of them. The story should have ended there, but a month, later she was abducted by the West and suffered violent sexual abuse at their hands before being told that sh...

  16. Automated dose estimation for lost or damaged dosimeters

    International Nuclear Information System (INIS)

    Thompson, W.L.; Deininger, R.J.

    1988-01-01

    This paper reports that some dosimetry vendors will compute doses for their customers' lost/damaged dosimeters based upon an average of recent dosimeter readings. However, the vendors usually require authorization from the customer for each such occurrence. Therefore, the tedious task of keeping track of the overdue status of each missing dosimeter and constantly notifying the vendor is still present. Also, depending on the monthly variability of a given person's doses, it may be more valid to use the employee's average dose, his/her highest dose over a recent period, an average dose of other employees with similar job duties for that period, or the maximum permissible dose. Thus, the task of estimating doses for lost/damaged dosimeters cannot be delegated to dosimetry vendor. Instead, the radiation safety department must sue the data supplied by the vendor as input for performing estimates. The process is performed automatically at the Medical Center Hospital of Vermont using a personal computer and a relational database

  17. Ecological aspects of the use of lost foam patterns

    Directory of Open Access Journals (Sweden)

    Z. Żółkiewicz

    2010-07-01

    Full Text Available The paper discusses some aspects of ecology in the use of lost foam patterns for piece production of large castings poured from ferrousalloys under the conditions of Metalodlew SA. Foundry. The technological processes used in the manufacture of castings are related with numerous hazards. Numerous problems requiring prompt solution occur also during the process of foundry mould pouring, to mention only various contaminants, air pollution, noise and other factors harmful to the human health and natural environment. Varioustechnological processes cause strenuous work conditions in foundry shops. Many of the publications that have appeared so far dealing withthe problems of environmental protection and hard work conditions in foundries [1, 2, 3, 4, 5, 6, 7, 8, 9] discuss in both general anddetailed way problems related with various pollutants, noise and other factors harmful to the human health and natural environment,responsible for hazards faced by foundry workers. Studies carried out by various R&D centres are mainly focussed on the problem of howto reduce the harmful effect of technological processes on the environment through modification of the already existing or development of new ecological and energy-saving materials and technologies. This paper shows the opportunities and threats resulting from the application of the Lost Foam Process in a foundry, which up to now has been using a more traditional technology.

  18. Light's labour's lost - policies for energy-efficient lighting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-29

    When William Shakepeare wrote Love's Labour's Lost he would have used light from tallow candles at a cost (today) of 12,000 British pounds per million-lumen hours. The same amount of light from electric lamps now costs only 2 pounds! But today's low-cost illumination still has a dark side. Globally, lighting consumes more electricity than is produced by either hydro or nuclear power and results in CO2 emissions equivalent to two thirds of the world's cars. A standard incandescent lamp may be much more efficient than a tallow candle, but it is far less efficient than a high-pressure sodium lamp. Were inefficient light sources to be replaced by the equivalent efficient ones, global lighting energy demand would be up to 40% less at a lower overall cost. Larger savings still could be realised through the intelligent use of controls, lighting levels and daylight. But achieving efficient lighting is not just a question of technology; it requires policies to transform current practice. This book documents the broad range of policy measures to stimulate efficient lighting that have already been implemented around the world and suggests new ways these could be strengthened to prevent light's labour's from being lost.

  19. Light's labour's lost - policies for energy-efficient lighting

    International Nuclear Information System (INIS)

    2006-01-01

    When William Shakepeare wrote Love's Labour's Lost he would have used light from tallow candles at a cost (today) of 12,000 British pounds per million-lumen hours. The same amount of light from electric lamps now costs only 2 pounds. But today's low-cost illumination still has a dark side. Globally, lighting consumes more electricity than is produced by either hydro or nuclear power and results in CO2 emissions equivalent to two thirds of the world's cars. A standard incandescent lamp may be much more efficient than a tallow candle, but it is far less efficient than a high-pressure sodium lamp. Were inefficient light sources to be replaced by the equivalent efficient ones, global lighting energy demand would be up to 40% less at a lower overall cost. Larger savings still could be realised through the intelligent use of controls, lighting levels and daylight. But achieving efficient lighting is not just a question of technology; it requires policies to transform current practice. This book documents the broad range of policy measures to stimulate efficient lighting that have already been implemented around the world and suggests new ways these could be strengthened to prevent light's labour's from being lost

  20. Finding Long Lost Lexell's Comet: The Fate of the First Discovered Near-Earth Object

    Science.gov (United States)

    Ye, Quan-Zhi; Wiegert, Paul A.; Hui, Man-To

    2018-04-01

    Jupiter-family Comet D/1770 L1 (Lexell) was the first discovered Near-Earth Object (NEO) and passed the Earth on 1770 July 1 at a recorded distance of 0.015 au. The comet was subsequently lost due to unfavorable observing circumstances during its next apparition followed by a close encounter with Jupiter in 1779. Since then, the fate of D/Lexell has attracted interest from the scientific community, and now we revisit this long-standing question. We investigate the dynamical evolution of D/Lexell based on a set of orbits recalculated using the observations made by Charles Messier, the comet’s discoverer, and find that there is a 98% chance that D/Lexell remains in the solar system by the year of 2000. This finding remains valid even if a moderate non-gravitational effect is imposed. Messier’s observations also suggest that the comet is one of the largest known near-Earth comets, with a nucleus of ≳10 km in diameter. This implies that the comet should have been detected by contemporary NEO surveys regardless of its activity level if it has remained in the inner solar system. We identify asteroid 2010 JL33 as a possible descendant of D/Lexell, with a 0.8% probability of chance alignment, but a direct orbital linkage of the two bodies has not been successfully accomplished. We also use the recalculated orbit to investigate the meteors potentially originating from D/Lexell. While no associated meteors have been unambiguously detected, we show that meteor observations can be used to better constrain the orbit of D/Lexell despite the comet being long lost.

  1. 21 CFR 1305.16 - Lost and stolen DEA Forms 222.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Lost and stolen DEA Forms 222. 1305.16 Section... II CONTROLLED SUBSTANCES DEA Form 222 § 1305.16 Lost and stolen DEA Forms 222. (a) If a purchaser ascertains that an unfilled DEA Form 222 has been lost, he or she must execute another in triplicate and...

  2. Years of potential life lost and life expectancy in schizophrenia

    DEFF Research Database (Denmark)

    Hjorthøj, Carsten; Stürup, Anne Emilie; McGrath, John J

    2017-01-01

    was least in the Asian study and greatest in Africa. The overall weighted average life expectancy was 64·7 years (95% CI 61·1-71·3), and was lower for men than women (59·9 years, 95% CI 55·5-64·3 vs 67·6 years, 63·1-72·1). Life expectancy was lowest in Asia and Africa. Timing of publication and risk of bias...... (Africa n=1, Asia n=1, Australia n=1, Europe n=7, and North America n=3) that involved up to 247 603 patients. Schizophrenia was associated with a weighted average of 14·5 years of potential life lost (95% CI 11·2-17·8), and was higher for men than women (15·9, 13·8-18·0 vs 13·6, 11·4-15·8). Loss...

  3. Response to The Lost Thing: Notes from a Secondary Classroom

    Directory of Open Access Journals (Sweden)

    Sandie Mourão

    2013-05-01

    Full Text Available This paper discusses students’ responses to the picturebook The Lost Thing (Tan, 2000 and its film (2010. It describes a small-scale project in a secondary school in Portugal, which involved 16-18 year-old students, learning English as a foreign language. Following a socio-constructivist approach to language learning and the basic tenets of reader response theory, discussion and an interpretative stance to meaning making were encouraged. The aim was to foster students’ appreciation of the visual during their interpretative discussions as well as developing their English language skills. This paper demonstrates how the picturebook in particular afforded the students with opportunities for language development through talk. It closes with notes on the implications of using picturebooks and their films in the classroom.

  4. Lost in Interpretation – Communicating Risk to the Public

    International Nuclear Information System (INIS)

    Meschenmoser, P.

    2016-01-01

    Communicating radiation incidents and emergencies to the public always has been challenging. No other type of emergency is related to such disproportional risk perception, so little public knowledge about the subject matter and so many contradicting expert analyses when it comes to public communications. The rise of social media and citizen journalism resulted in a dramatic acceleration of global communications and widespread misinformation. News does not break on television anymore but on Twitter, Facebook & Co. As a consequence, professional communicators not only have to take initiative considerably faster than in the past and deal with rumours. Their message has to be brief and on the point and is sometimes limited to just some 140 characters, the maximum length of a Tweet. More than ever it is essential to timely communicate in plain language and to clearly tell what needs to be done to be safe and to remain safe. Otherwise, the public will be lost in interpretation. (author)

  5. Lost in Interpretation – Communicating Risk to the Public

    International Nuclear Information System (INIS)

    Meschenmoser, P.

    2017-01-01

    Communicating radiation incidents and emergencies to the public always has been challenging. No other type of emergency is related to such disproportional risk perception, so little public knowledge about the subject matter and so many contradicting expert analyses when it comes to public communications. The rise of social media and citizen journalism resulted in a dramatic acceleration of global communications and widespread misinformation. News does not break on television anymore but on Twitter, Facebook & Co. As a consequence, professional communicators not only have to take initiative considerably faster than in the past and deal with rumours. Their message has to be brief and on the point and is sometimes limited to just some 140 characters, the maximum length of a Tweet. More than ever it is essential to timely communicate in plain language and to clearly tell what needs to be done to be safe and to remain safe. Otherwise, the public will be lost in interpretation. (author)

  6. Schumpeter's Evolution

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    reworking of his basic theory of economic evolution in Development from 1934, and this reworking was continued in Cycles from 1939. Here Schumpeter also tried to handle the statistical and historical evidence on the waveform evolution of the capitalist economy. Capitalism from 1942 modified the model...

  7. Galactic evolution

    International Nuclear Information System (INIS)

    Pagel, B.

    1979-01-01

    Ideas are considered concerning the evolution of galaxies which are closely related to those of stellar evolution and the origin of elements. Using information obtained from stellar spectra, astronomers are now able to consider an underlying process to explain the distribution of various elements in the stars, gas and dust clouds of the galaxies. (U.K.)

  8. Darwinian evolution

    NARCIS (Netherlands)

    Jagers op Akkerhuis, Gerard A.J.M.; Spijkerboer, Hendrik Pieter; Koelewijn, Hans Peter

    2016-01-01

    Darwinian evolution is a central tenet in biology. Conventionally, the defi nition of Darwinian evolution is linked to a population-based process that can be measured by focusing on changes in DNA/allele frequencies. However, in some publications it has been suggested that selection represents a

  9. Ecosystem of silicon utilizing organisms in the lost world

    Science.gov (United States)

    Das, S.

    2010-12-01

    It was Charles Darwin who first conceived the idea of “the Lost World” which spanned more than 80% of Earth History. This is about the rocks of the Precambrian period, in which Charles Darwin did not find any fossils during his study in 1859. Although Logan’s Foraminosphere and The Cyanosphere were the proposed concepts of the possible Precambrian life, however, these studies were flawed with non-biological artifacts, post-depositional contamination etc. Although now scientists believe the ‘hydrothermal cradle for life’ following the important studies in deep-sea vents, this is still a hypothetic view. All important experiments on the origin of life which were done with a reducing atmosphere, were also not correct. Scientists recently opined that probably life originated as silicon utilizing coacervates spontaneously in cosmos, and are transferred on the Earth in the Precambrian. These silicon utilizing coacervates could originate spontaneously in the Interstellar Medium (ISM) dust particles containing silicates with carbon, many organic molecules, and with mantles of ices. Thus ultraviolet ray from molecular hydrogen after collision excitation by electrons produced by cosmic-ray ionization may initiate seeds of life with formation of silicon utilizing coacervates; which are then scattered throughout the Universe. Similarly they can also originate in the GMCs, which have the clouds of dust and gases. These were also probably the last common ancestor (LCA) of all living creatures on the Earth. They are also still entering the surface of the Earth in small numbers during volcanic eruptions, blue lightning etc., but are quickly lost in the thickly inhabited Earth surface with ~ 1,00,000 diversified earthly species. These coacervates showed a direct correlation with non-cultivable spherical clusters found in the stratosphere, and the unknown spheroid bodies in microfossils ( ~ 3,200 Ma to >3,700 Ma) recovered in Australia, Africa and in Greenland. Both

  10. Lost Productivity in Stroke Survivors: An Econometrics Analysis.

    Science.gov (United States)

    Vyas, Manav V; Hackam, Daniel G; Silver, Frank L; Laporte, Audrey; Kapral, Moira K

    2016-01-01

    Stroke leads to a substantial societal economic burden. Loss of productivity among stroke survivors is a significant contributor to the indirect costs associated with stroke. We aimed to characterize productivity and factors associated with employability in stroke survivors. We used the Canadian Community Health Survey 2011-2012 to identify stroke survivors and employment status. We used multivariable logistic models to determine the impact of stroke on employment and on factors associated with employability, and used Heckman models to estimate the effect of stroke on productivity (number of hours worked/week and hourly wages). We included data from 91,633 respondents between 18 and 70 years and identified 923 (1%) stroke survivors. Stroke survivors were less likely to be employed (adjusted OR 0.39, 95% CI 0.33-0.46) and had hourly wages 17.5% (95% CI 7.7-23.7) lower compared to the general population, although there was no association between work hours and being a stroke survivor. We found that factors like older age, not being married, and having medical comorbidities were associated with lower odds of employment in stroke survivors in our sample. Stroke survivors are less likely to be employed and they earn a lower hourly wage than the general population. Interventions such as dedicated vocational rehabilitation and policies targeting return to work could be considered to address this lost productivity among stroke survivors. © 2016 S. Karger AG, Basel.

  11. Years of potential life lost due to motorcycle accidents

    Directory of Open Access Journals (Sweden)

    Flávia Emília Cavalcante Valença Fernandes

    2017-05-01

    Full Text Available Introduction: Traffic accidents represent a serious public health problem, because they kill approximately 1.24 million persons annually, and leave another 20 to 50 million with non-fatal lesions and traumatisms worldwide. In Brazil, in the year 2011, motorcyclists alone were responsible for one third of these deaths. Therefore, the aim of this study was to estimate the years of potential life lost due to motorcycle accidents, according to sex and age group, and analyze the trend of the indicator for the state of Pernambuco in the period from 2005 to 2014. Methods and Results an ecological study based on data from the System of Information about Mortality was used. The indicator and rate were calculated by using the age limit of 70 years. The linear regression model and Kruskal-Wallis and Mann-Whitney tests were used, at the level of significance of 5% and confidence of 95%. The most affected sex and age-range were men between 20-29 years of age. The rates followed a trend of growth in both sexes, in the young population with the exception of those from 10 to 19 years of age. Conclusions: This context points out the magnitude and precociousness of motorcycle accidents in both sexes and the young population.

  12. Microstructure and mechanical properties of lost foam cast 356 alloys

    Directory of Open Access Journals (Sweden)

    Qi-gui Wang

    2015-05-01

    Full Text Available Microstructure and mechanical properties of lost foam cast aluminum alloys have been investigated in both primary A356 (0.13% Fe and secondary 356 (0.47%. As expected, secondary 356 shows much higher content of Fe-rich intermetallic phases, and in particular the porosity in comparison with primary A356. The average area percent and size (length of Fe-rich intermetallics change from about 0.5% and 6 祄 in A356 to 2% and 25 祄 in 356 alloy. The average area percent and maximum size of porosity also increase from about 0.4% and 420 祄 to 1.4% and 600 祄, respectively. As a result, tensile ductility decreases about 60% and ultimate tensile strength declines about 8%. Lower fatigue strength was also experienced in the secondary 356 alloy. Low cycle fatigue (LCF strength decreased from 187 MPa in A356 to 159 MPa in 356 and high cycle fatigue (HCF strength also declined slightly from 68 MPa to 64 MPa.

  13. Novel technologies for the lost foam casting process

    Science.gov (United States)

    Jiang, Wenming; Fan, Zitian

    2018-03-01

    Lost foam casting (LFC) is a green precision casting process categorized as a near net forming technology. Yet, despite its popularity, it still suffers from some technological problems, such as poor filling ability of the castings, coarse and non-dense microstructure, low mechanical properties for the Al and Mg LFC processes, and defective carburization for the low carbon steel LFC process. These drawbacks restrict the development and widespread application of the LFC process. To solve these problems, the present study developed several novel LFC technologies, namely, LFC technologies under vacuum and low pressure, vibration solidification, and pressure solidification conditions; expendable shell casting technology; and preparation technology of bimetallic castings based on the LFC process. The results showed that the LFC under vacuum and low pressure evidently improved the filling ability and solved the oxidization problem of the alloys, which is suitable for producing complex and thinwall castings. The vibration and pressure solidifications increased the compactness of the castings and refined the microstructure, significantly improving the mechanical properties of the castings. The expendable shell casting technology could solve the pore, carburization, and inclusion defects of the traditional LFC method, obtaining castings with acceptable surface quality. Moreover, the Al/Mg and Al/Al bimetallic castings with acceptable metallurgical bonding were successfully fabricated using the LFC process. These proposed novel LFC technologies can solve the current technological issues and promote the technological progress of the LFC process.

  14. Big Bang Day : Afternoon Play - Torchwood: Lost Souls

    CERN Multimedia

    2008-01-01

    Martha Jones, ex-time traveller and now working as a doctor for a UN task force, has been called to CERN where they're about to activate the Large Hadron Collider. Once activated, the Collider will fire beams of protons together recreating conditions a billionth of a second after the Big Bang - and potentially allowing the human race a greater insight into what the Universe is made of. But so much could go wrong - it could open a gateway to a parallel dimension, or create a black hole - and now voices from the past are calling out to people and scientists have started to disappear... Where have the missing scientists gone? What is the secret of the glowing man? What is lurking in the underground tunnel? And do the dead ever really stay dead? Lost Souls is a spin-off from the award-winning BBC Wales TV production Torchwood. It stars John Barrowman, Freema Agyeman, Eve Myles, Gareth David-Lloyd, Lucy Montgomery (of Titty Bang Bang) and Stephen Critchlow.

  15. Years of life lost due to external radiation exposure

    International Nuclear Information System (INIS)

    Raicevic, J.J.; Merkle, J.M.; Ehrhardt, J.; Ninkovic, M.M.

    2002-01-01

    A new approach for calculation of the years of life lost per excess death (YLL) due to stochastic health effects is applied to external exposure pathways. The short-term external exposures are due to the passage of radioactive cloud (CL) and due to the skin and clothes contamination (SK). The long-term external exposure is the one from the radioactive material deposited on ground (GR). Three nuclides, 131 I , 137 Cs and 239 Pu with extremely wide range of the half-life are considered to examine its possible influence on the calculated YLL values. For each of these nuclides, the YLL is found as a decreasing function of the age at exposure and presented graphically in this paper. Another negative correlation is established between the fully averaged YLL and the duration of the nuclide's half-life has been found for protracted exposure (GR). On the other hand, the YLL for the short-term external exposures (CL and SK) practically does not depend on the nuclide's half-life. In addition, a weak YLL dependence of the dose was commented. (author)

  16. Who cares? The lost legacy of Archie Cochrane.

    Science.gov (United States)

    Askheim, Clemet; Sandset, Tony; Engebretsen, Eivind

    2017-03-01

    Over the last 20 years, the evidence-based medicine (EBM) movement has sought to develop standardised approaches to patient treatment by drawing on research results from randomised controlled trials (RCTs). The Cochrane Collaboration and its eponym, Archie Cochrane, have become symbols of this development, and Cochrane's book Effectiveness and Efficiency from 1972 is often referred to as the first sketch of what was to become EBM. In this article, we claim that this construction of EBM's historical roots is based on a selective reading of Cochrane's text. Through a close reading of this text, we show that the principal aim of modern EBM, namely to warrant clinical decisions based on evidence drawn from RCTs, is not part of Cochrane's original project. He had more modest ambitions for what RCTs can accomplish, and, more importantly, he was more concerned with care and equality than are his followers in the EBM movement. We try to reconstruct some of Cochrane's lost legacy and to articulate some of the important silences in Effectiveness and Efficiency From these clues it might be possible, we argue, to remodel EBM in a broader, more pluralistic, more democratic and less authoritarian manner. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  17. Management of Gout in a Hospital Setting: A Lost Opportunity.

    Science.gov (United States)

    Wright, Sarah; Chapman, Peter T; Frampton, Christopher; O'Donnell, John L; Raja, Rafi; Stamp, Lisa K

    2017-10-01

    Management of gout is frequently suboptimal. The aim of this study was to determine the proportion of patients presenting to Christchurch Hospital for a gout flare and to determine whether management for both acute flares and urate lowering was in accordance with international recommendations. A retrospective audit was undertaken of all admissions to Christchurch Hospital from June 1, 2013, to May 31, 2014, in which gout was coded as a primary or secondary discharge diagnosis. Information including demographics, comorbidities, concomitant medications, treatment of acute gout, and urate lowering was collected. A total of 235 acute admissions for gout in 216 individuals were identified. Eleven individuals had 2 admissions and 4 individuals had 3 admissions. In 95/235 admissions (40.4%), gout was the primary diagnosis. Gout accounted for 95/77,321 (0.12%) of acute admissions. The treatment of acute gout was prednisone monotherapy in 170/235 (72.3%) of admissions. Serum urate was measured at some point during 123/235 (52.3%) of admissions, with only 19/123 (15.4%) at target urate level (gout are similar to that observed in other studies. Failure to initiate, change, or recommend alterations in urate-lowering therapy to achieve target urate in people with gout admitted to hospital represents a significant lost opportunity to improve longterm gout management.

  18. Mitochondrial respiratory control is lost during growth factor deprivation.

    Science.gov (United States)

    Gottlieb, Eyal; Armour, Sean M; Thompson, Craig B

    2002-10-01

    The ability of cells to maintain a bioenergetically favorable ATP/ADP ratio confers a tight balance between cellular events that consume ATP and the rate of ATP production. However, after growth factor withdrawal, the cellular ATP/ADP ratio declines. To investigate these changes, mitochondria from growth factor-deprived cells isolated before the onset of apoptosis were characterized in vitro. Mitochondria from growth factor-deprived cells have lost their ability to undergo matrix condensation in response to ADP, which is accompanied by a failure to perform ADP-coupled respiration. At the time of analysis, mitochondria from growth factor-deprived cells were not depleted of cytochrome c and cytochrome c-dependent respiration was unaffected, demonstrating that the inhibition of the respiratory rate is not due to loss of cytochrome c. Agents that disrupt the mitochondrial outer membrane, such as digitonin, or maintain outer membrane exchange of adenine nucleotide, such as Bcl-x(L), restored ADP-dependent control of mitochondrial respiration. Together, these data suggest that the regulation of mitochondrial outer membrane permeability contributes to respiratory control.

  19. Lost fishing gear and litter at Gorringe Bank (NE Atlantic)

    Science.gov (United States)

    Vieira, Rui P.; Raposo, Isabel P.; Sobral, Paula; Gonçalves, Jorge M. S.; Bell, Katherine L. C.; Cunha, Marina R.

    2015-06-01

    Studies concerning marine litter have received great attention over the last several years by the scientific community mainly due to their ecological and economic impacts in marine ecosystems, from coastal waters to the deep ocean seafloor. The distribution, type and abundance of marine litter in Ormonde and Gettysburg, the two seamounts of Gorringe Bank, were analyzed from photo and video imagery obtained during ROV-based surveys carried out at 60-3015 m depths during the E/V Nautilus cruise NA017. Located approximately 125 nm southwest of Portugal, Gorringe Bank lays at the crossroad between the Atlantic and the Mediterranean and is therefore characterized by an intense maritime traffic and fishing activities. The high frequency of lost or discarded fishing gear, such as cables, longlines and nets, observed on Gorringe Bank suggests an origin mostly from fishing activities, with a clear turnover in the type of litter (mostly metal, glass and to a much lesser extent, plastic) with increasing depth. Litter was more abundant at the summit of Gorringe Bank (ca. 4 items·km- 1), decreasing to less than 1 item·km- 1 at the flanks and to ca. 2 items·km- 1 at greater depths. Nevertheless, litter abundance appeared to be lower than in continental margin areas. The results presented herein are a contribution to support further actions for the conservation of vulnerable habitats on Gorringe Bank so that they can continue contributing to fishery productivity in the surrounding region.

  20. Stellar evolution

    CERN Document Server

    Meadows, A J

    2013-01-01

    Stellar Evolution, Second Edition covers the significant advances in the understanding of birth, life, and death of stars.This book is divided into nine chapters and begins with a description of the characteristics of stars according to their brightness, distance, size, mass, age, and chemical composition. The next chapters deal with the families, structure, and birth of stars. These topics are followed by discussions of the chemical composition and the evolution of main-sequence stars. A chapter focuses on the unique features of the sun as a star, including its evolution, magnetic fields, act

  1. Echoes of the ancient skies the astronomy of lost civilizations

    CERN Document Server

    Krupp, E C

    2003-01-01

    ""It should be read by anyone even remotely interested in the long saga of the universe's profound and lasting influence on mankind's development."" - New Scientist""A grand book."" - Publishers Weekly""Dr. Krupp teaches us once more to look up at the stars and marvel."" - Ray BradburyThe intriguing world of archaeoastronomy - the study of ancient peoples' observations of the skies and the impact of what they saw on their cultural evolution - is the focus of this eminently readable and authoritative survey. Author E. C. Krupp, an astronomer, is the director of the Griffith Observatory in Los

  2. Zachary Solomon's Aggressions In Achieving Apotheosis Depicted In dan Brown's The Lost Symbol

    OpenAIRE

    FAIDAH, IRNA NUR

    2014-01-01

    Keywords: Aggression, Apotheosis, Hierarchy of Needs, The Lost Symbol, Self-Actualization, Zachary Solomon The basic concept of self-actualization is that people tend to be the best that they can be. This phenomenon is also portrayed in Dan Brown's The Lost Symbol. The Lost Symbol deals with a character named Zachary Solomon who wants to transform into status of God or it is called as apotheosis. In achieving the apotheosis, Zachary Solomon should satisfy his needs according to Abraham Masl...

  3. 29 CFR 779.251 - Goods that have lost their out-of-State identity.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Goods that have lost their out-of-State identity. 779.251... Coverage Interstate Inflow Test Under Prior Act § 779.251 Goods that have lost their out-of-State identity... been processed or manufactured so as to have lost their identity as out-of-State goods before they are...

  4. Kodak Digital Camera and The Lost Business Opportunity

    Institute of Scientific and Technical Information of China (English)

    Hamsa; Thota

    2012-01-01

    A systematic study of Kodak’s annual operations and business strategies during 2000-2010revealed that Kodak management faltered in transitioning the Kodak Company from an analog business model to a digital business model.In 2000 Kodak delivered strong performance and it appeared to be smart to be in the picture business.In 2002Kodak was the best-performing stock among companies that made up the Dow Jones Industrial Average.In 2005Kodak future looked bright.A confident Chairman and CEO Antonio M.Perez pronounced that by 2008he expected all of Kodak’s businesses to be leaders in their industry segments.In 2008Kodak remained as the most recognized and respected brands in the world but it played in the hyper competitive markets in which price and technological advances drove the market.So Kodak was unable to reap premium prices from its famous brand and it became a nonviable business due to sustained losses from continuing operations.During 2008-2012 Kodak fell from being a market leader to becoming a bankrupt Company.Using the analogy of"behind the power curve",this article shines light on Kodak’s crash to the ground,i.e.bankruptcy filing in 2012and asserts that Kodak management triggered the process of falling behind the power curve in 2000when it embraced the infoimaging strategy to extend the benefits of film.Kodak’s 2003digital business model and other strategies that followed it did not allow Kodak to become a strong competitor in the digital world.Kodak digital camera business became a lost business opportunity.

  5. Lost in Translation (LiT): IUPHAR Review 6.

    Science.gov (United States)

    Dollery, Colin T

    2014-05-01

    Translational medicine is a roller coaster with occasional brilliant successes and a large majority of failures. Lost in Translation 1 ('LiT1'), beginning in the 1950s, was a golden era built upon earlier advances in experimental physiology, biochemistry and pharmacology, with a dash of serendipity, that led to the discovery of many new drugs for serious illnesses. LiT2 saw the large-scale industrialization of drug discovery using high-throughput screens and assays based on affinity for the target molecule. The links between drug development and university sciences and medicine weakened, but there were still some brilliant successes. In LiT3, the coverage of translational medicine expanded from molecular biology to drug budgets, with much greater emphasis on safety and official regulation. Compared with R&D expenditure, the number of breakthrough discoveries in LiT3 was disappointing, but monoclonal antibodies for immunity and inflammation brought in a new golden era and kinase inhibitors such as imatinib were breakthroughs in cancer. The pharmaceutical industry is trying to revive the LiT1 approach by using phenotypic assays and closer links with academia. LiT4 faces a data explosion generated by the genome project, GWAS, ENCODE and the 'omics' that is in danger of leaving LiT4 in a computerized cloud. Industrial laboratories are filled with masses of automated machinery while the scientists sit in a separate room viewing the results on their computers. Big Data will need Big Thinking in LiT4 but with so many unmet medical needs and so many new opportunities being revealed there are high hopes that the roller coaster will ride high again. © 2014 The British Pharmacological Society.

  6. Training and replacing a 'lost generation' of uranium professionals

    International Nuclear Information System (INIS)

    Chalmers, M.S.

    2007-01-01

    It wasn't long ago, actually only a few years ago, when uranium companies and skilled uranium professionals receive little attention and limited interest from other sections of the mining and resource industries. Actually, there were many uranium professionals, whom in some cases, spent over a decade unwinding their CV's to limit the emphasis on uranium exploration and development from the past. Actually, when the bottom fell out of the uranium industry in the late 70's and early 80's there were literally tens of thousands of professionals internationally that were in a major regroup with their careers to get back into mining proper without the uranium connection and believe me, that wasn't always easy. As in most cases, there was no or limited places for uranium professionals wanting to stay in the industry and consequently, virtually all were forced to leave the sector. Who could have predicted that, after nearly 25 years of limited international investment and significant interest in new uranium exploration and development, that the price for yellowcake today would be in excess of US$100/pound? Concerns over energy security and global warming on top of the all-time high uranium price have really come together to make a true uranium renaissance. A renaissance which looks sounder and more sustainable than ever before. So, how is the industry facing a chronic shortage of experience and the huge task of training a multidisciplinary professional workforce going to cope? Effectively there is a 'lost generation' of professionals and very few people available or knowledgeable enough to train those new to the industry. This is a unique problem in the industry and likely more chronic than the other mining sectors, as typically the economic cycles are seven or eight years, not 25 years as has been seen with uranium

  7. Concern for Lost Income Following Donation Deters Some Patients From Talking to Potential Living Donors.

    Science.gov (United States)

    Rodrigue, James R; Schold, Jesse D; Mandelbrot, Didier A; Taber, David J; Phan, Van; Baliga, Prabhakar K

    2016-12-01

    Some living kidney donors report lost income during recovery from surgery. Little is known about whether concern for living donor's lost income affects the decision to undergo donation evaluation and the willingness of transplant candidates to discuss living kidney donation (LKD) with others. To examine whether transplant patients were told by potential donors about lost income concerns and whether patients chose not to discuss LKD with others due to lost income concerns. Kidney transplant patients (185 wait-listed candidates, 171 deceased donor recipients, and 100 live donor recipients) at 2 centers completed a questionnaire to assess whether concern about donor's lost income was a consideration in discussion about LKD with others. One-third (32%) were told by a family member/friend that they were willing to donate but were concerned about potential lost income. The majority of those who expressed financial concern (64%) did not initiate donation evaluation. Many patients (42%) chose not to discuss living donation with a family member/friend due to concern about the impact of lost income on the donor. In the multivariable model, lower annual household income was the only statistically significant predictor of both having a potential donor expressing lost income concern and choosing not to talk to someone because of lost income concern. Findings from the current study underscore how concern about income loss for living donors may affect decision-making by both transplant candidates and potential donors.

  8. Genome-wide analysis of Dongxiang wild rice (Oryza rufipogon Griff.) to investigate lost/acquired genes during rice domestication.

    Science.gov (United States)

    Zhang, Fantao; Xu, Tao; Mao, Linyong; Yan, Shuangyong; Chen, Xiwen; Wu, Zhenfeng; Chen, Rui; Luo, Xiangdong; Xie, Jiankun; Gao, Shan

    2016-04-26

    It is widely accepted that cultivated rice (Oryza sativa L.) was domesticated from common wild rice (Oryza rufipogon Griff.). Compared to other studies which concentrate on rice origin, this study is to genetically elucidate the substantially phenotypic and physiological changes from wild rice to cultivated rice at the whole genome level. Instead of comparing two assembled genomes, this study directly compared the Dongxiang wild rice (DXWR) Illumina sequencing reads with the Nipponbare (O. sativa) complete genome without assembly of the DXWR genome. Based on the results from the comparative genomics analysis, structural variations (SVs) between DXWR and Nipponbare were determined to locate deleted genes which could have been acquired by Nipponbare during rice domestication. To overcome the limit of the SV detection, the DXWR transcriptome was also sequenced and compared with the Nipponbare transcriptome to discover the genes which could have been lost in DXWR during domestication. Both 1591 Nipponbare-acquired genes and 206 DXWR-lost transcripts were further analyzed using annotations from multiple sources. The NGS data are available in the NCBI SRA database with ID SRP070627. These results help better understanding the domestication from wild rice to cultivated rice at the whole genome level and provide a genomic data resource for rice genetic research or breeding. One finding confirmed transposable elements contribute greatly to the genome evolution from wild rice to cultivated rice. Another finding suggested the photophosphorylation and oxidative phosphorylation system in cultivated rice could have adapted to environmental changes simultaneously during domestication.

  9. Main pumps lost incident in the nuclear power plant Atucha I. Modelling with RELAP5/MOD3.2

    International Nuclear Information System (INIS)

    Ventura, M.A.; Rosso, R.D.

    1998-01-01

    Time evolution of natural circulation in the nuclear power plant Atucha I (CNA-I), in a main pumps lost incident because of the lost of external power feed, is analyzed. It leads to a strong stop transient, without an important blow down, from a forced nominal flow to a natural circulation one. The results are obtained from RELAP5/MOD3.2 code's modeling. The study is based on the refrigeration conditions analysis, during the first minutes of the reactor out of service. Previously to the transient, work had been done to obtain the plant steady state, with design parameters in operation conditions at 100 % of power. The object is that the actual plant state would be represented. In this way, each plant part (steam generators, reactor, pressurizer, pumps) had been modeled in separated form with the appropriate boundary conditions, to be used in the whole circuit simulation. The developed model, had been validated making use of the comparison between the values obtained to the principal thermodynamic parameters with the plant recorded values, in the same incident. The results are satisfactory in a way. On the other hand, it has suggested some modeling changes. The RELAP5/MOD3.2 capability to model the thermodynamic phenomena in a PHWR plant has been verified when, according to the mentioned incident, the flow pass from a nominal forced flow, to one which is governed by natural circulation, still with the CNA-I untypical design conditions. (author) [es

  10. Lost productivity in four European countries among patients with rheumatic disorders: are absenteeism and presenteeism transferable?

    Science.gov (United States)

    Knies, Saskia; Candel, Math J J M; Boonen, Annelies; Evers, Silvia M A A; Ament, Andre J H A; Severens, Johan L

    2012-09-01

    When national pharmacoeconomic guidelines are compared, different recommendations are identified on how to identify, measure and value lost productivity, leading to difficulties when comparing lost productivity estimates across countries. From a transferability point of view, the question arises of whether differences between countries regarding lost productivity are the result of using different calculation methods (methodological differences) or of other between-country differences. When lost productivity data differ significantly across countries, the transferability of lost productivity data across countries is hindered. The objective of this study was to investigate whether country of residence has a significant influence on the quantity of lost productivity among patients with rheumatic disorders. Confounding factors that might differ between countries were corrected for, while the methodology used to identify and measure lost productivity was kept the same. This question was investigated by means of an online questionnaire filled out by 200 respondents with a rheumatic disorder per country in four European countries, namely the Netherlands, the UK, Germany and France. In addition to those regarding lost productivity, the questionnaire contained questions about patient characteristics, disability insurance, disease characteristics, quality of life and job characteristics as these variables are expected to influence lost productivity in terms of absenteeism and presenteeism. The data were analysed by regression analyses, in which different components - being absent in last 3 months, number of days absent and presenteeism - of lost productivity were the main outcome measures and other variables, such as gender, impact of disease, shift work, job control, partial disability and overall general health, were corrected for. The results showed that country sometimes has a significant influence on lost productivity and that other variables such as, for example, age

  11. Modeling soil processes - are we lost in diversity?

    Science.gov (United States)

    Vogel, Hans-Joerg; Schlüter, Steffen

    2015-04-01

    Soils are among the most complex environmental systems. Soil functions - e.g. production of biomass, habitat for organisms, reactor for and storage of organic matter, filter for ground water - emerge from a multitude of processes interacting at different scales. It still remains a challenge to model and predict these functions including their stability and resilience towards external perturbations. As an inherent property of complex systems it is prohibitive to unravel all the relevant process in all detail to derive soil functions and their dynamics from first principles. Hence, when modeling soil processes and their interactions one is close to be lost in the overwhelming diversity and spatial heterogeneity of soil properties. In this contribution we suggest to look for characteristic similarities within the hyperdimensional state space of soil properties. The underlying hypothesis is that this state space is not evenly and/or randomly populated but that processes of self organization produce attractors of physical, chemical and biological properties which can be identified. (The formation of characteristic soil horizons is an obvious example). To render such a concept operational a suitable and limited set of indicators is required. Ideally, such indicators are i) related to soil functions, ii) are measurable and iii) are integral measures of the relevant physical, chemical and biological soil properties. This would allow for identifying suitable attractors. We will discuss possible indicators and will focus on soil structure as an especially promising candidate. It governs the availability of water and gas, it effects the spatial distribution of organic matter and, moreover, it forms the habitat of soil organisms and it is formed by soil biota. Quantification of soil structural properties became possible only recently with the development of more powerful tools for non-invasive imaging. Future research need to demonstrate in how far these tools can be used to

  12. 27 CFR 25.282 - Beer lost by fire, theft, casualty, or act of God.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Beer lost by fire, theft... TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Refund or Adjustment of Tax or Relief From Liability § 25.282 Beer lost by fire, theft, casualty, or act of God. (a) General. The tax paid by...

  13. 38 CFR 12.24 - Operation of lost and found service.

    Science.gov (United States)

    2010-07-01

    ... custodian. VA Form 3771, Record of Lost or Found Article, will be used for recording articles of any... articles and to recover items which have been reported lost. Currency, including readily negotiable... closing hour. The currency or negotiable instruments will be delivered to the agent cashier before the...

  14. Assessment of net lost revenue adjustment mechanisms for utility DSM programs

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, L.W.

    1995-01-01

    Utility shareholders can lose money on demand-side management (DSM) investments between rate cases. Several industry analysts argue that the revenues lost from utility DSM programs are an important financial disincentive to utility DSM investment. A key utility regulatory reform undertaken since 1989 allows utilities to recover the lost revenues incurred through successful operation of DSM programs. Explicitly defined net lost revenue adjustment (NLRA) mechanisms are states` preferred approach to lost revenue recovery from DSM programs. This report examines the experiences states and utilities are having with the NLRA approach. The report has three objectives. First, we determine whether NLRA is a feasible and successful approach to removing the lost-revenue disincentive to utility operation of DSM programs. Second, we identify the conditions linked to successful implementation of NLRA mechanisms in different states and assess whether NLRA has changed utility investment behavior. Third, we suggest improvements to NLRA mechanisms. We first identify states with NLRA mechanisms where utilities are recovering lost revenues from DSM programs. We interview staff at regulatory agencies in all these states and utility staff in four states. These interviews focus on the status of NLRA, implementation issues, DSM measurement issues, and NLRA results. We also analyze regulatory agency orders on NLRA, as well as associated testimony, reports, and utility lost revenue recovery filings. Finally, we use qualitative and quantitative indicators to assess NLRA`s effectiveness. Contrary to the concerns raised by some industry analysts, our results indicate NLRA is a feasible approach to the lost-revenue disincentive.

  15. 29 CFR 779.250 - Goods that have not lost their out-of-State identity.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Goods that have not lost their out-of-State identity. 779...-State identity. Goods which are purchased or received by the enterprise from within the State will be... and have not lost their identity as out-of-State goods before they are purchased or received by the...

  16. Cost optimization in the (S-1,S) lost sales inventory model with multiple demand classes

    NARCIS (Netherlands)

    Kranenburg, A.A.; Houtum, van G.J.J.A.N.

    2007-01-01

    For the (S-1,S) lost sales inventory model with multiple demand classes that have different lost sales penalty cost parameters, three accurate and efficient heuristic algorithms are presented that, at a given base stock level, aim to find optimal values for the critical levels, i.e., values that

  17. Arabidopsis RIBA Proteins: Two out of Three Isoforms Have Lost Their Bifunctional Activity in Riboflavin Biosynthesis

    Science.gov (United States)

    Hiltunen, Hanna-Maija; Illarionov, Boris; Hedtke, Boris; Fischer, Markus; Grimm, Bernhard

    2012-01-01

    Riboflavin serves as a precursor for flavocoenzymes (FMN and FAD) and is essential for all living organisms. The two committed enzymatic steps of riboflavin biosynthesis are performed in plants by bifunctional RIBA enzymes comprised of GTP cyclohydrolase II (GCHII) and 3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBPS). Angiosperms share a small RIBA gene family consisting of three members. A reduction of AtRIBA1 expression in the Arabidopsis rfd1mutant and in RIBA1 antisense lines is not complemented by the simultaneously expressed isoforms AtRIBA2 and AtRIBA3. The intensity of the bleaching leaf phenotype of RIBA1 deficient plants correlates with the inactivation of AtRIBA1 expression, while no significant effects on the mRNA abundance of AtRIBA2 and AtRIBA3 were observed. We examined reasons why both isoforms fail to sufficiently compensate for a lack of RIBA1 expression. All three RIBA isoforms are shown to be translocated into chloroplasts as GFP fusion proteins. Interestingly, both AtRIBA2 and AtRIBA3 have amino acid exchanges in conserved peptides domains that have been found to be essential for the two enzymatic functions. In vitro activity assays of GCHII and DHBPS with all of the three purified recombinant AtRIBA proteins and complementation of E. coli ribA and ribB mutants lacking DHBPS and GCHII expression, respectively, confirmed the loss of bifunctionality for AtRIBA2 and AtRIBA3. Phylogenetic analyses imply that the monofunctional, bipartite RIBA3 proteins, which have lost DHBPS activity, evolved early in tracheophyte evolution. PMID:23203051

  18. Y2K affiliation, immediate pedestrian density, and helping responses to lost letters.

    Science.gov (United States)

    Bridges, F S; Thompson, P C

    2001-06-01

    Of 75 letters "lost" in Florida, 41 were returned in the mail (the helpful response). Immediate pedestrian density was significantly related to nonhelping responses. The greater the number of subjects passing by a lost letter, the less likely any one of them would respond to it. The rates of return did vary with the addressees' affiliations. Returned responses for the affiliates, Y2K Arkbuilders and the Believers of God's Judgement Against Homosexuals: Y2K Millennium Bug, were substantially lower than for the affiliate, Y2K Computer Repair & Programming, Inc. Returns for the Believers of God's Judgement Against Homosexuals: Y2K Millennium Bug affiliate were significantly lower than for the Y2K Arkbuilders affiliate. Variables such as sex, race, and estimated age of subjects were not associated with helping to return a lost letter. The rate of return of lost letters is not the only important measure to be examined in studies using lost letters.

  19. Lost Muon Study for the Muon G-2 Experiment at Fermilab*

    Energy Technology Data Exchange (ETDEWEB)

    Ganguly, S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Crnkovic, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Morse, W. M. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-05-19

    The Fermilab Muon g-2 Experiment has a goal of measuring the muon anomalous magnetic moment to a precision of 140 ppb - a fourfold improvement over the 540 ppb precision obtained by the BNL Muon g-2 Experiment. Some muons in the storage ring will interact with material and undergo bremsstrahlung, emitting radiation and loosing energy. These so called lost muons will curl in towards the center of the ring and be lost, but some of them will be detected by the calorimeters. A systematic error will arise if the lost muons have a different average spin phase than the stored muons. Algorithms are being developed to estimate the relative number of lost muons, so as to optimize the stored muon beam. This study presents initial testing of algorithms that can be used to estimate the lost muons by using either double or triple detection coincidences in the calorimeters.

  20. Animal evolution

    DEFF Research Database (Denmark)

    Nielsen, Claus

    This book provides a comprehensive analysis of evolution in the animal kingdom. It reviews the classical, morphological information from structure and embryology, as well as the new data gained from studies using immune stainings of nerves and muscles and blastomere markings, which makes it possi......This book provides a comprehensive analysis of evolution in the animal kingdom. It reviews the classical, morphological information from structure and embryology, as well as the new data gained from studies using immune stainings of nerves and muscles and blastomere markings, which makes...

  1. Estimation of lost circulation amount occurs during under balanced drilling using drilling data and neural network

    Directory of Open Access Journals (Sweden)

    Pouria Behnoud far

    2017-09-01

    Full Text Available Lost circulation can cause an increase in time and cost of operation. Pipe sticking, formation damage and uncontrolled flow of oil and gas may be consequences of lost circulation. Dealing with this problem is a key factor to conduct a successful drilling operation. Estimation of lost circulation amount is necessary to find a solution. Lost circulation is influenced by different parameters such as mud weight, pump pressure, depth etc. Mud weight, pump pressure and flow rate of mud should be designed to prevent induced fractures and have the least amount of lost circulation. Artificial neural network is useful to find the relations of parameters with lost circulation. Genetic algorithm is applied on the achieved relations to determine the optimum mud weight, pump pressure, and flow rate. In an Iranian oil field, daily drilling reports of wells which are drilled using UBD technique are studied. Asmari formation is the most important oil reservoir of the studied field and UBD is used only in this interval. Three wells with the most, moderate and without lost circulation are chosen. In this article, the effect of mud weight, depth, pump pressure and flow rate of pump on lost circulation in UBD of Asmari formation in one of the Southwest Iranian fields is studied using drilling data and artificial neural network. In addition, the amount of lost circulation is predicted precisely with respect to two of the studied parameters using the presented correlations and the optimum mud weight, pump pressure and flow rate are calculated to minimize the lost circulation amount.

  2. Energy-Saving Melting and Revert Reduction Technology (E-SMARRT): Lost Foam Thin Wall - Feasibility of Producing Lost Foam Castings in Aluminum and Magnesium Based Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Fasoyinu, Yemi [CanmetMATERIALS; Griffin, John A. [University of Alabama - Birmingham

    2014-03-31

    With the increased emphasis on vehicle weight reduction, production of near-net shape components by lost foam casting will make significant inroad into the next-generation of engineering component designs. The lost foam casting process is a cost effective method for producing complex castings using an expandable polystyrene pattern and un-bonded sand. The use of un-bonded molding media in the lost foam process will impose less constraint on the solidifying casting, making hot tearing less prevalent. This is especially true in Al-Mg and Al-Cu alloy systems that are prone to hot tearing when poured in rigid molds partially due to their long freezing range. Some of the unique advantages of using the lost foam casting process are closer dimensional tolerance, higher casting yield, and the elimination of sand cores and binders. Most of the aluminum alloys poured using the lost foam process are based on the Al-Si system. Very limited research work has been performed with Al-Mg and Al-Cu type alloys. With the increased emphasis on vehicle weight reduction, and given the high-strength-to-weight-ratio of magnesium, significant weight savings can be achieved by casting thin-wall (≤ 3 mm) engineering components from both aluminum- and magnesium-base alloys.

  3. The costs of diabetes among Australians aged 45-64 years from 2015 to 2030: projections of lost productive life years (PLYs), lost personal income, lost taxation revenue, extra welfare payments and lost gross domestic product from Health&WealthMOD2030.

    Science.gov (United States)

    Schofield, Deborah; Shrestha, Rupendra N; Cunich, Michelle M; Passey, Megan E; Veerman, Lennert; Tanton, Robert; Kelly, Simon J

    2017-01-09

    To project the number of people aged 45-64 years with lost productive life years (PLYs) due to diabetes and related costs (lost income, extra welfare payments, lost taxation revenue); and lost gross domestic product (GDP) attributable to diabetes in Australia from 2015 to 2030. A simulation study of how the number of people aged 45-64 years with diabetes increases over time (based on population growth and disease trend data) and the economic losses incurred by individuals and the government. Cross-sectional outputs of a microsimulation model (Health&WealthMOD2030) which used the Australian Bureau of Statistics' Survey of Disability, Ageing and Carers 2003 and 2009 as a base population and integrated outputs from two microsimulation models (Static Incomes Model and Australian Population and Policy Simulation Model), Treasury's population and labour force projections, and chronic disease trends data. Australian population aged 45-64 years in 2015, 2020, 2025 and 2030. Lost PLYs, lost income, extra welfare payments, lost taxation revenue, lost GDP. 18 100 people are out of the labour force due to diabetes in 2015, increasing to 21 400 in 2030 (18% increase). National costs consisted of a loss of $A467 million in annual income in 2015, increasing to $A807 million in 2030 (73% increase). For the government, extra annual welfare payments increased from $A311 million in 2015 to $A350 million in 2030 (13% increase); and lost annual taxation revenue increased from $A102 million in 2015 to $A166 million in 2030 (63% increase). A loss of $A2.1 billion in GDP was projected for 2015, increasing to $A2.9 billion in 2030 attributable to diabetes through its impact on PLYs. Individuals incur significant costs of diabetes through lost PLYs and lost income in addition to disease burden through human suffering and healthcare costs. The government incurs extra welfare payments, lost taxation revenue and lost GDP, along with direct healthcare costs. Published by the BMJ

  4. Representing Evolution

    DEFF Research Database (Denmark)

    Hedin, Gry

    2012-01-01

    . This article discusses Willumsen's etching in the context of evolutionary theory, arguing that Willumsen is a rare example of an artist who not only let the theory of evolution fuel his artistic imagination, but also concerned himself with a core issue of the theory, namely to what extent it could be applied...

  5. Security Evolution.

    Science.gov (United States)

    De Patta, Joe

    2003-01-01

    Examines how to evaluate school security, begin making schools safe, secure schools without turning them into fortresses, and secure schools easily and affordably; the evolution of security systems into information technology systems; using schools' high-speed network lines; how one specific security system was developed; pros and cons of the…

  6. Cepheid evolution

    International Nuclear Information System (INIS)

    Becker, S.A.

    1984-05-01

    A review of the phases of stellar evolution relevant to Cepheid variables of both Types I and II is presented. Type I Cepheids arise as a result of normal post-main sequence evolutionary behavior of many stars in the intermediate to massive range of stellar masses. In contrast, Type II Cepheids generally originate from low-mass stars of low metalicity which are undergoing post core helium-burning evolution. Despite great progress in the past two decades, uncertainties still remain in such areas as how to best model convective overshoot, semiconvection, stellar atmospheres, rotation, and binary evolution as well as uncertainties in important physical parameters such as the nuclear reaction rates, opacity, and mass loss rates. The potential effect of these uncertainties on stellar evolution models is discussed. Finally, comparisons between theoretical predictions and observations of Cepheid variables are presented for a number of cases. The results of these comparisons show both areas of agreement and disagreement with the latter result providing incentive for further research

  7. Venom Evolution

    Indian Academy of Sciences (India)

    IAS Admin

    Therefore, the platypus sequence was studied to quantify the role of gene duplication in the evolution of venom. ... Platypus venom is present only in males and is used for asserting dominance over com- petitors during the ... Certain toxin gene families are known to re- peatedly evolve through gene duplications. The rapidly ...

  8. Short-term Lost Productivity per Victim: Intimate Partner Violence, Sexual Violence, or Stalking.

    Science.gov (United States)

    Peterson, Cora; Liu, Yang; Kresnow, Marcie-Jo; Florence, Curtis; Merrick, Melissa T; DeGue, Sarah; Lokey, Colby N

    2018-05-15

    The purpose of this study is to estimate victims' lifetime short-term lost productivity because of intimate partner violence, sexual violence, or stalking. U.S. nationally representative data from the 2012 National Intimate Partner and Sexual Violence Survey were used to estimate a regression-adjusted average per victim (female and male) and total population number of cumulative short-term lost work and school days (or lost productivity) because of victimizations over victims' lifetimes. Victims' lost productivity was valued using a U.S. daily production estimate. Analysis was conducted in 2017. Non-institutionalized adults with some lifetime exposure to intimate partner violence, sexual violence, or stalking (n=6,718 respondents; survey-weighted n=130,795,789) reported nearly 741 million lost productive days because of victimizations by an average of 2.5 perpetrators per victim. The adjusted per victim average was 4.9 (95% CI=3.9, 5.9) days, controlling for victim, perpetrator, and violence type factors. The estimated societal cost of this short-term lost productivity was $730 per victim, or $110 billion across the lifetimes of all victims (2016 USD). Factors associated with victims having a higher number of lost days included a higher number of perpetrators and being female, as well as sexual violence, physical violence, or stalking victimization by an intimate partner perpetrator, stalking victimization by an acquaintance perpetrator, and sexual violence or stalking victimization by a family member perpetrator. Short-term lost productivity represents a minimum economic valuation of the immediate negative effects of intimate partner violence, sexual violence, and stalking. Victims' lost productivity affects family members, colleagues, and employers. Published by Elsevier Inc.

  9. Nudging Evolution?

    OpenAIRE

    Katharine N. Farrell; Andreas Thiel

    2013-01-01

    This Special Feature, "Nudging Evolution? Critical Exploration of the Potential and Limitations of the Concept of Institutional Fit for the Study and Adaptive Management of Social-Ecological Systems," aims to contribute toward the development of social theory and social research methods for the study of social-ecological system dynamics. Our objective is to help strengthen the academic discourse concerning if, and if so, how, to what extent, and in what concrete ways the concept of institut...

  10. Community Evolution

    OpenAIRE

    Saganowski, Stanisław; Bródka, Piotr; Kazienko, Przemysław

    2016-01-01

    The continuous interest in the social network area contributes to the fast development of this field. The new possibilities of obtaining and storing data facilitate deeper analysis of the entire social network, extracted social groups and single individuals as well. One of the most interesting research topic is the network dynamics and dynamics of social groups in particular, it means analysis of group evolution over time. It is the natural step forward after social community extraction. Havi...

  11. Visibly marked and microchipped lost dogs have a higher chance to find their owners in Belgrade

    Directory of Open Access Journals (Sweden)

    Marijana Vučinić

    2015-03-01

    Full Text Available The aim of the study was to analyse the demographic characteristics of lost and found dogs in Belgrade, Serbia. The demographic data concerning the 246 lost and 81 found dogs in the period of 5 consecutive years (January, 2009 to January 2014 was sampled and analysed from the data bases of four organizations for animal protection in Belgrade. The recovery rate of lost dogs and the chance to be reunited again with their owners was 33%. The highest recovery rate was estimated in the category of lost dogs with visible marks such as tags or collars (30%.The chi-square test disclosed that besides dogs with special visible marks, significantly more females, light colour coated, friendly/sociable and neutered dogs were reunited with their owners (P<0.0001.

  12. Matthew's Messianic Shepherd-king: In search of “the lost sheep of ...

    African Journals Online (AJOL)

    p1243322

    the Messianic Shepherd-King expectation with its attending expectations for territorial ... Messianic Shepherd-King: In Search of the Lost Sheep of the House of Israel. September. 2007. Berlin: De Gruyter. ...... Exile in the early. Persian Period”.

  13. Ductile cast iron obtaining by Inmold method with use of LOST FOAM process

    Directory of Open Access Journals (Sweden)

    T. Pacyniak

    2010-01-01

    Full Text Available The possibility of manufacturing of ductile cast iron castings by Inmold method with use of LOST FOAM process was presented in this work. The spheroidization was carried out by magnesium master alloy in amounts of 1% casting mass. Nodulizer was located in the reactive chamber in the gating system made of foamed polystyrene. Pretests showed, that there are technical possibilities of manufacturing of casts from ductile cast iron in the LOST FOAM process with use of spheroidization in mould.

  14. Cluster evolution

    International Nuclear Information System (INIS)

    Schaeffer, R.

    1987-01-01

    The galaxy and cluster luminosity functions are constructed from a model of the mass distribution based on hierarchical clustering at an epoch where the matter distribution is non-linear. These luminosity functions are seen to reproduce the present distribution of objects as can be inferred from the observations. They can be used to deduce the redshift dependence of the cluster distribution and to extrapolate the observations towards the past. The predicted evolution of the cluster distribution is quite strong, although somewhat less rapid than predicted by the linear theory

  15. CHEMICAL EVOLUTION

    Energy Technology Data Exchange (ETDEWEB)

    Calvin, Melvin

    1965-06-01

    How did life come to be on the surface of the earth? Darwin himself recognized that his basic idea of evolution by variation and natural selection must be a continuous process extending backward in time through that period in which the first living things arose and into the period of 'Chemical Evolution' which preceded it. We are approaching the examination of these events by two routes. One is to seek for evidence in the ancient rocks of the earth which were laid down prior to that time in which organisms capable of leaving their skeletons in the rocks to be fossilized were in existence. This period is sometime prior to approximately 600 million years ago. The earth is believed to have taken its present form approximately 4700 million years ago. We have found in rocks whose age is about 1000 million years certain organic molecules which are closely related to the green pigment of plants, chlorophyll. This seems to establish that green plants were already fluorishing prior to that time. We have now found in rocks of still greater age, namely, 2500 million years, the same kinds of molecules mentioned above which can be attributed to the presence of living organisms. If these molecules are as old as the rocks, we have thus shortened the time available for the generation of the complex biosynthetic sequences which give rise to these specific hydrocarbons (polyisoprenoids) to less than 2000 million years.

  16. The monetary value of human lives lost due to neglected tropical diseases in Africa.

    Science.gov (United States)

    Kirigia, Joses Muthuri; Mburugu, Gitonga N

    2017-12-18

    Neglected tropical diseases (NTDs) are an important cause of death and disability in Africa. This study estimates the monetary value of human lives lost due to NTDs in the continent in 2015. The lost output or human capital approach was used to evaluate the years of life lost due to premature deaths from NTDs among 10 high/upper-middle-income (Group 1), 17 middle-income (Group 2) and 27 low-income (Group 3) countries in Africa. The future losses were discounted to their present values at a 3% discount rate. The model was re-analysed using 5% and 10% discount rates to assess the impact on the estimated total value of human lives lost. The estimated value of 67 860 human lives lost in 2015 due to NTDs was Int$ 5 112 472 607. Out of that, 14.6% was borne by Group 1, 57.7% by Group 2 and 27.7% by Group 3 countries. The mean value of human life lost per NTD death was Int$ 231 278, Int$ 109 771 and Int$ 37 489 for Group 1, Group 2 and Group 3 countries, respectively. The estimated value of human lives lost in 2015 due to NTDs was equivalent to 0.1% of the cumulative gross domestic product of the 53 continental African countries. Even though NTDs are not a major cause of death, they impact negatively on the productivity of those affected throughout their life-course. Thus, the case for investing in NTDs control should also be influenced by the value of NTD morbidity, availability of effective donated medicines, human rights arguments, and need to achieve the NTD-related target 3.3 of the United Nations Sustainable Development Goal 3 (on health) by 2030.

  17. Hours Lost to Planned and Unplanned Dental Visits Among US Adults.

    Science.gov (United States)

    Kelekar, Uma; Naavaal, Shillpa

    2018-01-11

    Poor oral health is associated with lost hours at work or school, which may affect a person's productivity. The objective of our study was to estimate work or school hours lost to dental visits among adults aged 18 and older by the types of visits (emergency or unplanned; routine, planned, or orthodontic; or cosmetic) and to determine the factors associated with hours lost. We used the most recent Oral Health Supplement data, from the 2008 National Health Interview Survey (NHIS), to estimate the total hours lost at work or school for dental visits among adults in the United States. The associations of the hours lost in unplanned and planned dental visits with socioeconomic characteristics, oral health status, and affordability were calculated. We used χ 2 tests and logistic regression to determine associations at P work or school hours were lost annually for dental care in the United States, of which 92.4 million hours were for emergency (unplanned) care (0.99 h/adult), 159.8 million for routine (planned) care or orthodontic care (1.71 h/adult), and 68.6 million for cosmetic care (0.73 h/adult). Adults with poor oral health were more likely to lose one or more hours in unplanned dental visits (OR = 5.60; 95% confidence interval [CI], 3.25-9.63) than those who reported very good oral health. Not being able to afford dental care was positively associated with more work hours lost in unplanned care (odds ratio [OR] = 2.56; 95% CI, 1.76-3.73). Compared with Hispanic adults, non-Hispanic white adults (OR = 2.09; 95% CI, 1.40-3.11) and non-Hispanic Asian adults and adults of other races/ethnicities (OR =1.91; 95% CI, 1.06-3.47) were more likely to lose any hours for planned care. Consistently, those with more than a high school education were more likely to lose any hours in planned care (OR = 1.39; 95% CI, 1.06-1.83) than those with a high school education or less. Dental problems result in hours lost from work and may adversely affect a person's productivity. There is

  18. [Comparative adaptation of crowns of selective laser melting and wax-lost-casting method].

    Science.gov (United States)

    Li, Guo-qiang; Shen, Qing-yi; Gao, Jian-hua; Wu, Xue-ying; Chen, Li; Dai, Wen-an

    2012-07-01

    To investigate the marginal adaptation of crowns fabricated by selective laser melting (SLM) and wax-lost-casting method, so as to provide an experimental basis for clinic. Co-Cr alloy full crown were fabricated by SLM and wax-lost-casting for 24 samples in each group. All crowns were cemented with zinc phosphate cement and cut along longitudinal axis by line cutting machine. The gap between crown tissue surface and die was measured by 6-point measuring method with scanning electron microscope (SEM). The marginal adaptation of crowns fabricated by SLM and wax-lost-casting were compared statistically. The gap between SLM crowns were (36.51 ± 2.94), (49.36 ± 3.31), (56.48 ± 3.35), (42.20 ± 3.60) µm, and wax-lost-casting crowns were (68.86 ± 5.41), (58.86 ± 6.10), (70.62 ± 5.79), (69.90 ± 6.00) µm. There were significant difference between two groups (P casting method and SLM method provide acceptable marginal adaptation in clinic, and the marginal adaptation of SLM is better than that of wax-lost-casting method.

  19. Modeling SOL evolution during disruptions

    International Nuclear Information System (INIS)

    Rognlien, T.D.; Cohen, R.H.; Crotinger, J.A.

    1996-01-01

    We present the status of our models and transport simulations of the 2-D evolution of the scrape-off layer (SOL) during tokamak disruptions. This evolution is important for several reasons: It determines how the power from the core plasma is distributed on material surfaces, how impurities from those surfaces or from gas injection migrate back to the core region, and what are the properties of the SOL for carrying halo currents. We simulate this plasma in a time-dependent fashion using the SOL transport code UEDGE. This code models the SOL plasma using fluid equations of plasma density, parallel momentum (along the magnetic field), electron energy, ion energy, and neutral gas density. A multispecies model is used to follow the density of different charge-states of impurities. The parallel transport is classical but with kinetic modifications; these are presently treated by flux limits, but we have initiated more sophisticated models giving the correct long-mean-free path limit. The cross-field transport is anomalous, and one of the results of this work is to determine reasonable values to characterize disruptions. Our primary focus is on the initial thermal quench phase when most of the core energy is lost, but the total current is maintained. The impact of edge currents on the MHD equilibrium will be discussed

  20. Om religion og evolution

    DEFF Research Database (Denmark)

    Geertz, Armin W.

    2011-01-01

    for kulturens kausale virkning på den menneskelige kognition og ikke mindst den hominine evolution. Ud fra, hvad vi ved om den menneskelige evolution, ses det, at den hominine evolution har en dybde, som sjældent medtænkes i teorier og hypoteser om den menneskelige evolution. Den menneskelige evolution er...

  1. Paradise Lost: Difference between Adam and Eve’s Lament on Leaving Paradise - A Contrastive Analysis

    Directory of Open Access Journals (Sweden)

    Sara Torres Servín

    2013-01-01

    Full Text Available The difference between Adam and Eve’s lament on leaving Paradise in Milton’s Paradise Lost is striking in its contrastive content and depth. This paper analyzes the difference that exists between the feelings and spiritual attitudes that Adam and Eve express on the occasion when they are informed by the angel Michael that they have to abandon the Garden of Eden. It is a comparison of their lament in order to understand the contrast of the two attitudes that Milton wove in the tapestry that Paradise Lost is. The paper also explores male and female roles in Paradise Lost and concludes that Adam and Eve are equal yet different, that difference being the cause of their contrastive ways of expressing their sorrow. Adam and Eve manifest two contrastive worldviews in opposition, one spiritual (heavenly, and the other material (earthly.

  2. Realidade Ambígua: imersão em The Lost Experience

    Directory of Open Access Journals (Sweden)

    Dario Mesquita

    2010-10-01

    Full Text Available O estudo discurrerá sobre como o Alternate Reality Game (ARG foi utilizado como uma extensão imersiva do universo de Lost através da campanha The Lost Experience (LTE. Assim, faremos um levantamento sobre alguns aspectos pertinentes do seriado. Então será realizado um estudo sobre a estrutura dos ARGs, partindo de seus principais preceitos que buscam mimetizar um mundo ficcional acoplado ao mundo real utilizando os meios de comunicação. Por seguinte analisaremos o LTE, que surgiu assumidamente como uma campanha com objetivos publicitários, com o propósito de enriquecer a experiência narrativa do público de Lost.

  3. Design, Development and Testing of a Drillable Straddle Packer for Lost Circulation Control in Geothermal Drilling

    Energy Technology Data Exchange (ETDEWEB)

    Gabaldon, J.; Glowka, D.A.; Gronewald, P.; Knudsen, S.D.; Raymond, D.W.; Staller, G.E.; Westmoreland, J.J.; Whitlow, G.L.; Wise, J.L.; Wright, E.K.

    1999-04-01

    Lost Circulation is a widespread problem encountered when drilling geothermal wells, and often represents a substantial portion of the cost of drilling a well. The U.S. Department of Energy sponsors research and development work at Sandia National Laboratories in an effort to reduce these lost circulation expenditures. Sandia has developed a down hole tool that improves the effectiveness and reduces th cost of lost circulation cement treatment while drilling geothermal wells. This tool, the Drillable Straddle Packer, is a low-cost disposable device that is used to isolate the loss zone and emplace the cement treatment directly into the region of concern. This report documents the design and development of the Drillabe Straddle Packer, the laboratory and field test results, and the design package that is available to transfer this technology to industry users.

  4. Location-based technologies for supporting elderly pedestrian in "getting lost" events.

    Science.gov (United States)

    Pulido Herrera, Edith

    2017-05-01

    Localization-based technologies promise to keep older adults with dementia safe and support them and their caregivers during getting lost events. This paper summarizes mainly technological contributions to support the target group in these events. Moreover, important aspects of the getting lost phenomenon such as its concept and ethical issues are also briefly addressed. Papers were selected from scientific databases and gray literature. Since the topic is still in its infancy, other terms were used to find contributions associated with getting lost e.g. wandering. Trends of applying localization systems were identified as personal locators, perimeter systems and assistance systems. The first system barely considered the older adult's opinion, while assistance systems may involve context awareness to improve the support for both the elderly and the caregiver. Since few studies report multidisciplinary work with a special focus on getting lost, there is not a strong evidence of the real efficiency of localization systems or guidelines to design systems for the target group. Further research about getting lost is required to obtain insights for developing customizable systems. Moreover, considering conditions of the older adult might increase the impact of developments that combine localization technologies and artificial intelligence techniques. Implications for Rehabilitation Whilst there is no cure for dementia such as Alzheimer's, it is feasible to take advantage of technological developments to somewhat diminish its negative impact. For instance, location-based systems may provide information to early diagnose the Alzheimer's disease by assessing navigational impairments of older adults. Assessing the latest supportive technologies and methodologies may provide insights to adopt strategies to properly manage getting lost events. More user-centered designs will provide appropriate assistance to older adults. Namely, customizable systems could assist older adults

  5. Lost working years due to mental disorders: an analysis of the Norwegian disability pension registry.

    Directory of Open Access Journals (Sweden)

    Ann Kristin Knudsen

    Full Text Available OBJECTIVES: Mental disorders are prevalent diagnoses in disability benefit statistics, with awards often granted at younger age than for other diagnoses. We aimed to compare the number of lost working years following disability benefit award for mental disorders versus other diagnostic groups. METHODS: Data from the complete Norwegian official registry over disability benefit incidence, including primary diagnoses, were analyzed for the period 2001 to 2003 (N = 77,067, a time-period without any reform in the disability benefit scheme. Lost working years due to disability benefit award before scheduled age retirement at age 67 were calculated. RESULTS: Musculoskeletal disorders were the commonest reason for disability benefit awards (36.3% with mental disorders in second place (24.0%. However, mental disorders were responsible for the most working years lost (33.8% compared with musculoskeletal disorders (29.4%. Individuals awarded disability benefit for a mental disorder were on average 8.9 years younger (46.1 years than individuals awarded for a musculoskeletal disorder (55.0 years, and 6.9 years younger than individuals awarded for any other somatic disorder (53.0 years. Anxiety and depressive disorders were the largest contributors to lost working years within mental disorders. CONCLUSION: Age at award is highly relevant when the total burden of different diagnoses on disability benefits is considered. There is great disparity in total number of lost working years due to disability benefit award for different diagnostic groups. The high number of lost working years from mental disorders has serious consequences for both the individual and for the wider society and economy.

  6. Telomerase lost?

    Czech Academy of Sciences Publication Activity Database

    Mason, J. M.; Randall, T. A.; Čapková Frydrychová, Radmila

    2016-01-01

    Roč. 125, č. 1 (2016), s. 65-73 ISSN 0009-5915 R&D Projects: GA ČR GA14-07172S Grant - others:GA JU(CZ) 052/2013/P; GA JU(CZ) 038/2014/P; European Union Seventh Framework Programme(CZ) 316304 Program:FP7 Institutional support: RVO:60077344 Keywords : telomerase * DNA sequences * Bombyx mori Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.414, year: 2016 http://link.springer.com/article/10.1007%2Fs00412-015-0528-7

  7. Lost criteria

    Directory of Open Access Journals (Sweden)

    Aleksandr Egorovich Manoylov

    2010-01-01

    Full Text Available Physicians have been found to be inadequately aware of the structure of the causes of headache, vertigo, and their clinical importance in patients with essential hypertension. Incorrect ideas lead to the unfounded application of diagnostic techniques for imaging the great arteries of the head and to extremely simplified approaches to treating cerebrovascular diseases as short-term courses of therapy with vasoactive and metabolic agents.

  8. Conformality lost

    International Nuclear Information System (INIS)

    Kaplan, David B.; Lee, Jong-Wan; Son, Dam T.; Stephanov, Mikhail A.

    2009-01-01

    We consider zero-temperature transitions from conformal to nonconformal phases in quantum theories. We argue that there are three generic mechanisms for the loss of conformality in any number of dimensions: (i) fixed point goes to zero coupling, (ii) fixed point runs off to infinite coupling, or (iii) an IR fixed point annihilates with a UV fixed point and they both disappear into the complex plane. We give both relativistic and nonrelativistic examples of the last case in various dimensions and show that the critical behavior of the mass gap behaves similarly to the correlation length in the finite temperature Berezinskii-Kosterlitz-Thouless (BKT) phase transition in two dimensions, ξ∼exp(c/|T-T c | 1/2 ). We speculate that the chiral phase transition in QCD at large number of fermion flavors belongs to this universality class, and attempt to identify the UV fixed point that annihilates with the Banks-Zaks fixed point at the lower end of the conformal window.

  9. Lost Priorities

    National Research Council Canada - National Science Library

    Hernandez, Rhett

    1998-01-01

    A review of the administration's National Security Strategy highlights the administration's inability to identify what's really important and focus its limited resources on accomplishing the essential...

  10. Paradise lost

    International Nuclear Information System (INIS)

    Johnson, G.

    1980-01-01

    The United States conducted 66 atmospheric nuclear weapons tests in the Marshall Islands. Twenty-two years later the authorities continue to disagree on when the islands will be safe for resettlement. This article discusses the events that have occurred in the past 30 years

  11. The Old English Genesis and Milton’s Paradise Lost: the characterisation of Satan

    Directory of Open Access Journals (Sweden)

    Elisa Ramazzina

    2016-07-01

    Full Text Available The aim of this study is to determine whether and to what extent the English poet John Milton may have been influenced in the composition of Paradise Lost by the Old English poem known as Genesis B. The paper will examine similarities and dif-ferences in the characterisation of Satan and of the temptation of Adam and Eve in both poems. The comparison between two of the illuminations of the Junius 11 ms. and the corresponding passages in Paradise Lost will be part of the analysis.

  12. The Old English Genesis and Milton's Paradise Lost: the characterisation of Satan

    OpenAIRE

    Ramazzina, Elisa

    2016-01-01

    The aim of this study is to determine whether and to what extent the English poet John Milton may have been influenced in the composition of Paradise Lost by the Old English poem known as Genesis B. The paper will examine similarities and dif-ferences in the characterisation of Satan and of the temptation of Adam and Eve in both poems. The comparison between two of the illuminations of the Junius 11 ms. and the corresponding passages in Paradise Lost will be part of the analysis.

  13. Can increasing adult vaccination rates reduce lost time and increase productivity?

    Science.gov (United States)

    Rittle, Chad

    2014-12-01

    This article addresses limited vaccination coverage by providing an overview of the epidemiology of influenza, pertussis, and pneumonia, and the impact these diseases have on work attendance for the worker, the worker's family, and employer profit. Studies focused on the cost of vaccination programs, lost work time, lost employee productivity and acute disease treatment are discussed, as well as strategies for increasing vaccination coverage to reduce overall health care costs for employers. Communicating the benefits of universal vaccination for employees and their families and combating vaccine misinformation among employees are outlined. Copyright 2014, SLACK Incorporated.

  14. Love in Love’s Labour’s Lost: Ontological Foundation or Laughing Matter?

    OpenAIRE

    Mousley, Andy

    2015-01-01

    Love’s labour is often lost in Shakespeare’s (un)romantic comedy because love is folly and lovers, ridiculous. We know, however, that Shakespeare delights in paradoxes and reversals which alert us to the possibility of finding wisdom in folly and folly in self-professed wisdom. Given the insisted-upon interchangeability of wisdom and folly in Shakespeare’s plays, how can we be confident of being able to tell them apart? If lovers are foolish in Love’s Labour’s Lost then what wisdom might ther...

  15. Lost Opportunities in the Buildings Sector: Energy-Efficiency Analysis and Results

    Energy Technology Data Exchange (ETDEWEB)

    Dirks, James A.; Anderson, David M.; Hostick, Donna J.; Belzer, David B.; Cort, Katherine A.

    2008-09-12

    This report summarizes the results and the assumptions used in an analysis of the potential “lost efficiency opportunities” in the buildings sector. These targets of opportunity are those end-uses, applications, practices, and portions of the buildings market which are not currently being addressed, or addressed fully, by the Building Technologies Program (BTP) due to lack of resources. The lost opportunities, while a significant increase in effort and impact in the buildings sector, still represent only a small portion of the full technical potential for energy efficiency in buildings.

  16. Lost foam casting of aluminum alloy-SiCp composite material

    International Nuclear Information System (INIS)

    Baalasuburamaniam, R.; Cvetnic, C.; Ravindran, C.

    2002-01-01

    Metal matrix composites are a viable alternative to cast irons in automotive components with possible increase in strength-to-weight ratio. Lost foam casting of aluminum alloy matrix composite containing 20 volume percent SiC was carried out at 690, 730, and 770 o C with a view to determining the effects of cooling rate on microstructure, particle distribution, microporosity and mechanical properties. These results were compared with those for the matrix material cast under similar conditions. The results and the correlations are of particular interest as there is no published literature on lost foam casting of composite materials. (author)

  17. The M/M/1 queue with inventory, lost sale and general lead times

    DEFF Research Database (Denmark)

    Saffari, Mohammad; Asmussen, Søren; Haji, Rasoul

    We consider an M/M/1 queueing system with inventory under the (r,Q) policy and with lost sales, in which demands occur according to a Poisson process and service times are exponentially distributed. All arriving customers during stockout are lost. We derive the stationary distributions of the joint...... queue length (number of customers in the system) and on-hand inventory when lead times are random variables and can take various distributions. The derived stationary distributions are used to formulate long-run average performance measures and cost functions in some numerical examples....

  18. Pressing back: Split Britches' Lost Lounge and the retro performativity of lesbian performance.

    Science.gov (United States)

    Eschen, Nicole

    2013-01-01

    Using theories of affect and queer temporality, this article examines Split Britches' Lost Lounge as lesbian resistance to the pressures to remember or forget the past, condemn or embrace the future. In this piece, butch-femme duo Peggy Shaw and Lois Weaver develop a retro performativity that pushes back against systems that strive to make lesbianism invisible, private, and apolitical. Through performances that resignify past pop culture artifacts, particularly the duo of Louis Prima and Keely Smith, Shaw and Weaver perform a past that is simultaneously lost and embodied, pressuring the audience to reconsider notions of progress and beauty.

  19. Quasars and galactic evolution

    CERN Document Server

    Woltjer, L

    1978-01-01

    The evolution of quasars is discussed. It is noted that substantial clustering may be present at faint magnitudes. The relationship between quasar evolution and galactic evolution is considered. (4 refs).

  20. Nudging Evolution?

    Directory of Open Access Journals (Sweden)

    Katharine N. Farrell

    2013-12-01

    Full Text Available This Special Feature, "Nudging Evolution? Critical Exploration of the Potential and Limitations of the Concept of Institutional Fit for the Study and Adaptive Management of Social-Ecological Systems," aims to contribute toward the development of social theory and social research methods for the study of social-ecological system dynamics. Our objective is to help strengthen the academic discourse concerning if, and if so, how, to what extent, and in what concrete ways the concept of institutional "fit" might play a role in helping to develop better understanding of the social components of interlinkages between the socioeconomic-cultural and ecological dynamics of social-ecological systems. Two clearly discernible patterns provide a map of this Special Feature: (1 One pattern is the authors' positions regarding the place and role of normativity within their studies and assessment of institutional fit. Some place this at the center of their studies, exploring phenomena endogenous to the process of defining what constitutes institutional fit, whereas others take the formation of norms as a phenomenon exogenous to their study. (2 Another pattern is the type of studies presented: critiques and elaborations of the theory, methods for judging qualities of fit, and/or applied case studies using the concept. As a body of work, these contributions highlight that self-understanding of social-ecological place, whether explicit or implicit, constitutes an important part of the study object, i.e., the role of institutions in social-ecological systems, and that this is, at the same time, a crucial point of reference for the scholar wishing to evaluate what constitutes institutional fit and how it might be brought into being.

  1. Caverns Measureless to Man: Subterranean Rivers and Adventurous Masculinities in the Victorian Lost World Novel

    DEFF Research Database (Denmark)

    McCausland, Elly

    2018-01-01

    This article examines a recurring trope in late Victorian ‘lost world’ adventure novels: the terrifying descent down a subterranean river into the bowels of the earth. More than simply an exciting episode, the subterranean river journey reflects narrative strategies and thematic concerns key to b...

  2. Search for lost or orphan radioactive sources based on Nal gamma spectrometry

    DEFF Research Database (Denmark)

    Aage, Helle Karina; Korsbech, Uffe C C

    2003-01-01

    Within recent decades many radioactive sources have been lost, stolen, or abandoned, and some have caused contamination or irradiation of people. Therefore reliable methods for source recovery are needed. The use of car borne NaI(Tl) detectors is discussed. Standard processing of spectra in general...

  3. Lost Instruction: The Disparate Impact of the School Discipline Gap in California

    Science.gov (United States)

    Losen, Daniel J.; Whitaker, Amir

    2017-01-01

    This report is the first to analyze California's school discipline data as measured by days of missed instruction due to suspension. The state reports the number of suspensions for each district, disaggregated by racial/ethnic groups, but it does not provide any information on how much instructional time was lost. The authors used information from…

  4. MARKET RISK ASSESSMENT USING EXPECTED TAIL LOST (ETL – PECULIARITIES AND APPLICATION

    Directory of Open Access Journals (Sweden)

    Sergey Radukanov

    2017-12-01

    Full Text Available Measuring market risk is explained by using Expected Tail Lost in the article. Its advantages, disadvantages and range of application are pointed out. The basic calculation stages are emphasized in MS EXCEL. Market risk measurement is carried out towards the shares of the company General Motors Company (GM

  5. Study The role of latent variables in lost working days by Structural Equation Modeling Approach

    Directory of Open Access Journals (Sweden)

    Meysam Heydari

    2016-12-01

    Full Text Available Background: Based on estimations, each year about 250 million work-related injuries and many temporary or permanent disabilities occur which most are preventable. Oil and Gas industries are among industries with high incidence of injuries in the world. The aim of this study has investigated  the role and effect of different risk management variables on lost working days (LWD in the seismic projects. Methods: This study was a retrospective, cross-sectional and systematic analysis, which was carried out on occupational accidents between 2008-2015(an 8 years period in different seismic projects for oilfield exploration at Dana Energy (Iranian Seismic Company. The preliminary sample size of the study were 487accidents. A systems analysis approach were applied by using root case analysis (RCA and structural equation modeling (SEM. Tools for the data analysis were included, SPSS23 and AMOS23  software. Results: The mean of lost working days (LWD, was calculated 49.57, the final model of structural equation modeling showed that latent variables of, safety and health training factor(-0.33, risk assessment factor(-0.55 and risk control factor (-0.61 as direct causes significantly affected of lost working days (LWD in the seismic industries (p< 0.05. Conclusion: The finding of present study revealed that combination of variables affected in lost working days (LWD. Therefore,the role of these variables in accidents should be investigated and suitable programs should be considered for them.

  6. Matthew's Messianic Shepherd-king: In search of “the lost sheep of ...

    African Journals Online (AJOL)

    p1243322

    , the son of David, the ... Messianism – that is, the view that the future among other things will involve the restoration of the Davidic ... “sheep without a shepherd” (9:36), and the “lost sheep of the house of Israel”. (10:6) are to be understood as ...

  7. Matthew's Messianic Shepherd-king: In search of “the lost sheep of ...

    African Journals Online (AJOL)

    The article intends to grasp the meaning of the phrase “the lost sheep of the house of Israel” in the Matthean logia of 10:5b-6 (and 15:24). It shows that in recent Matthean research the phrase has become an abstract salvation-historical category disconnected from narrative and historical particularity. However, generally ...

  8. The casting of western sculpture during the XIXth century: sand casting versus lost wax casting

    NARCIS (Netherlands)

    Beentjes, T.P.C.

    2014-01-01

    This paper will discuss research into bronze casting techniques as practiced during the XIXth and early XXth century. Both natural sand casting (fonte au sable naturel) and lost wax casting (fonte à la cire perdue) were employed during this period and sometimes rivalled for commissions. Before the

  9. 27 CFR 24.65 - Claims for wine or spirits lost or destroyed in bond.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Claims for wine or spirits... Provisions Claims § 24.65 Claims for wine or spirits lost or destroyed in bond. (a) Claim for remission of... 27 CFR part 70, subpart F. A claim filed under this paragraph with respect to spirits, wine, or...

  10. On possible parent bodies of Innisfree, Lost City and Prgibram meteorites.

    Science.gov (United States)

    Rozaev, A. E.

    1994-12-01

    Minor planets 1981 ET3 and Seleucus are possible parent bodies of Innisfree and Lost City meteorites, asteroid Mithra is the most probable source of Prgibram meteorite. The conclusions are based on the Southworth - Hawkins criterion with taking into account of the motion constants (Tisserand coefficient, etc.) and minimal distances between orbits at present time.

  11. Psychology's Lost Boy: Will the Real Little Albert Please Stand Up?

    Science.gov (United States)

    Griggs, Richard A.

    2015-01-01

    This article is concerned with the recent debate about the identity of psychology's lost boy-Little Albert, the infant subject in Watson and Rayner's classic experiment on fear conditioning. For decades, psychologists and psychology students have been intrigued by the mystery of Albert's fate. Now two evidentiary-based solutions to…

  12. Two replenishment strategies for the lost sales inventory model: a comparison

    NARCIS (Netherlands)

    Donselaar, van K.H.; Kok, de A.G.; Rutten, W.G.M.M.

    1996-01-01

    For the lost sales inventory system we distinguish two different replenishment strategies. The simplest strategy is the classical ‘fixed reorder level’ replenishment rule: every period the inventory position in the system is raised up to a fixed quantity S. For this simple strategy we derive and

  13. Exploring the Premise of Lost Altruism: Content Analysis of Two Codes of Ethics

    Science.gov (United States)

    Haddara, Wael; Lingard, Lorelei

    2017-01-01

    As an ideal, altruism has long enjoyed privileged status in medicine and medical education. As a practice, altruism is perceived to be in decline in the current generation. A number of educational efforts are underway to reclaim this "lost value" of medicine. In this paper we explore constructions of altruism over a defined period of…

  14. "Lixue" (?? "Ihak") the Lost Art: Confucianism as a Form of Cultivation of Mind

    Science.gov (United States)

    Han, Hyong-Jo

    2016-01-01

    This article approaches Confucianism as a lost art of living and asks how we can make it relevant again for us. Central to this approach is the cultivation of heart-mind ("Xinxue," ??) designed to help cure ourselves of self-oblivion and self-centeredness so prevalent in our culture today. It is based on the idea of "Li" (?),…

  15. Years of life lost to incarceration: inequities between Aboriginal and non-Aboriginal Canadians.

    Science.gov (United States)

    Owusu-Bempah, Akwasi; Kanters, Steve; Druyts, Eric; Toor, Kabirraaj; Muldoon, Katherine A; Farquhar, John W; Mills, Edward J

    2014-06-11

    Aboriginal representation in Canadian correctional institutions has increased rapidly over the past decade. We calculated "years of life lost to incarceration" for Aboriginal and non-Aboriginal Canadians. Incarceration data from provincial databases were used conjointly with demographic data to estimate rates of incarceration and years of life lost to provincial incarceration in (BC) and federal incarceration, by Aboriginal status. We used the Sullivan method to estimate the years of life lost to incarceration. Aboriginal males can expect to spend approximately 3.6 months in federal prison and within BC spend an average of 3.2 months in custody in the provincial penal system. Aboriginal Canadians on average spend more time in custody than their non-Aboriginal counterparts. The ratio of the Aboriginal incarceration rate to the non-Aboriginal incarceration rate ranged from a low of 4.28 in Newfoundland and Labrador to a high of 25.93 in Saskatchewan. Rates of incarceration at the provincial level were highest among Aboriginals in Manitoba with an estimated rate of 1377.6 individuals in prison per 100,000 population (95% confidence interval [CI]: 1311.8-1443.4). The results indicate substantial differences in life years lost to incarceration for Aboriginal versus non-Aboriginal Canadians. In light of on-going prison expansion in Canada, future research and policy attention should be paid to the public health consequences of incarceration, particularly among Aboriginal Canadians.

  16. Marine magnetic studies over a lost wellhead in Palk Bay, Cauvery Basin, India

    Digital Repository Service at National Institute of Oceanography (India)

    Ramana, M.V.; Subrahmanyam, V.; Sarma, K.V.L.N.S.; Seshavataram, B.T.V.

    Close grid marine magnetic surveys in the vicinity of a drill well site PH 9-1 in Palk Bay revealed that the area is characterized by smooth magnetic field except for a local anomaly caused by a lost wellhead. The smooth magnetic field is attributed...

  17. Health care and lost productivity costs of overweight and obesity in New Zealand.

    Science.gov (United States)

    Lal, Anita; Moodie, Marj; Ashton, Toni; Siahpush, Mohammad; Swinburn, Boyd

    2012-12-01

    To estimate the costs of health care and lost productivity attributable to overweight and obesity in New Zealand (NZ) in 2006. A prevalence-based approach to costing was used in which costs were calculated for all cases of disease in the year 2006. Population attributable fractions (PAFs) were calculated based on the relative risks obtained from large cohort studies and the prevalence of overweight and obesity. For each disease, the PAF was multiplied by the total health care cost. The costs of lost productivity associated with premature mortality were estimated using both the Human Capital approach (HCA) and Friction Cost approach (FCA). Health care costs attributable to overweight and obesity were estimated to be NZ$686m or 4.5% of New Zealand's total health care expenditure in 2006. The costs of lost productivity using the FCA were estimated to be NZ$98m and NZ$225m using the HCA. The combined costs of health care and lost productivity using the FCA were $784m and $911m using the HCA. The cost burden of overweight and obesity in NZ is considerable. Policies and interventions are urgently needed to reduce the prevalence of obesity thereby decreasing these substantial costs. © 2012 The Authors. ANZJPH © 2012 Public Health Association of Australia.

  18. September 1930, Lisbon: Aleister Crowley’s lost diary of his Portuguese trip

    NARCIS (Netherlands)

    Pasi, M.

    2012-01-01

    Aleister Crowley’s diary for the period of his travel to Portugal and his meeting with Fernando Pessoa has long been considered lost or inaccessible. However, a copy has been finally found and is here presented and published for the first time. The analysis of the diary allows us to have a fuller

  19. 77 FR 73739 - Endangered and Threatened Wildlife and Plants; Designation of Critical Habitat for Lost River...

    Science.gov (United States)

    2012-12-11

    ... sucker and shortnose sucker under the Act. For more information on the biology and ecology of the Lost... conservation biology principles. We received responses from two of the peer reviewers. We reviewed all comments... microgram ([micro]g) per liter (L). The peer reviewer stated that this is the World Health Organization...

  20. 76 FR 76337 - Endangered and Threatened Wildlife and Plants; Designation of Critical Habitat for Lost River...

    Science.gov (United States)

    2011-12-07

    ... information on the Lost River sucker's and shortnose sucker's biology and habitat, population abundance and... consumed chironomid larvae as well as micro-crustaceans (amphipods, copepods, cladocerans, and ostracods... information above, we identify an abundant food base, including a broad array of chironomids, micro...

  1. Paradise Lost and Found: Obedience, Disobedience, and Storytelling in C.S. Lewis and Philip Pullman.

    Science.gov (United States)

    Wood, Naomi

    2001-01-01

    Considers how in the fantasy series "The Chronicles of Narnia" and "His Dark Materials," by C.S. Lewis and Philip Pullman respectively, the authors use symbols and themes from "Paradise Lost." Notes that each author's narrative choice uses his view of cosmic order to persuade readers that obedience should be…

  2. Workers' compensation loss prevention representative contact and risk of lost-time injury in construction policyholders.

    Science.gov (United States)

    Schofield, Katherine E; Alexander, Bruce H; Gerberich, Susan G; MacLehose, Richard F

    2017-09-01

    Insurance loss prevention (LP) representatives have access and contact with businesses and employees to provide targeted safety and health resources. Construction firms, especially those smaller in size, are a high-risk population. This research evaluated the association between LP rep contact and risk for lost-time injuries in construction policyholders. Workers' compensation data were utilized to track LP rep contact with policyholders and incidence of lost-time injury over time. Survival analysis with repeated events modeling calculated hazard ratios (HR) and 95% confidence intervals (CI). Compared no LP contact, one contact was associated with a 27% reduction of risk (HR=0.73, CI=0.65-0.82), two with a 41% (HR=0.59, CI=0.51-0.68), and three or more contacts with a 28% reduction of risk (HR=0.72, CI=0.65-0.81). LP reps appear to be a valuable partner in efforts to reduce injury burden. Their presence or contact with policyholders is consistent with reduction in overall incidence of lost-time injuries. Reduction in lost-time injuries, resulting in reduced workers' compensation costs for policyholders and insurance companies, builds a business-case for safety and injury prevention. LP reps are often a low or no-cost benefit for insurance policyholders and may be an important injury prevention resource for small firms and/or those with lack of safety resources and staff. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  3. PRODUCTION OF ROTARY ENGINES’ PARTS FROM ALUMINUM ALLOYS USING LOST FOAM CASTING PROCESS

    Directory of Open Access Journals (Sweden)

    E. I. Marukovich

    2018-01-01

    Full Text Available The production technology of casting details for rotary engine from the aluminum alloy АК12М2 is developed. The bulk density of expanded polystyrene to ensure the best quality of the surface of castings has been experimentally established. The lost foam casting shop was organized in the experimental department of the Institute.

  4. Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters

    NARCIS (Netherlands)

    Tetteh, Paul W.; Basak, Onur; Farin, Henner F.; Wiebrands, Kay; Kretzschmar, Kai; Begthel, Harry; van den Born, Maaike; Korving, Jeroen; De Sauvage, Frederic; Van Es, Johan H.; Van Oudenaarden, Alexander; Clevers, Hans

    2016-01-01

    Intestinal crypts display robust regeneration upon injury. The relatively rare secretory precursors can replace lost stem cells, but it is unknown if the abundant enterocyte progenitors that express the Alkaline phosphate intestinal (Alpi) gene also have this capacity. We created an

  5. The orphaning experience: descriptions from Ugandan youth who have lost parents to HIV/AIDS

    Directory of Open Access Journals (Sweden)

    Ssebunnya Joshua

    2010-02-01

    Full Text Available Abstract The HIV/AIDS epidemic has continued to pose significant challenges to countries in Sub-Saharan Africa. Millions of African children and youth have lost parents to HIV/AIDS leaving a generation of orphans to be cared for within extended family systems and communities. The experiences of youth who have lost parents to the HIV/AIDS epidemic provide an important ingress into this complex, evolving, multi-dimensional phenomenon. A fundamental qualitative descriptive study was conducted to develop a culturally relevant and comprehensive description of the experiences of orphanhood from the perspectives of Ugandan youth. A purposeful sample of 13 youth who had lost one or both parents to HIV/AIDS and who were affiliated with a non-governmental organization providing support to orphans were interviewed. Youth orphaned by HIV/AIDS described the experience of orphanhood beginning with parental illness, not death. Several losses were associated with the death of a parent including lost social capitol, educational opportunities and monetary assets. Unique findings revealed that youth experienced culturally specific stigma and conflict which was distinctly related to their HIV/AIDS orphan status. Exploitation within extended cultural family systems was also reported. Results from this study suggest that there is a pressing need to identify and provide culturally appropriate services for these Ugandan youth prior to and after the loss of a parent(s.

  6. 78 FR 2441 - Agency Information Collection Activities: Proposed Collection; Comments Requested; Report of Lost...

    Science.gov (United States)

    2013-01-11

    ... Stolen ATF F 5400.30, Intrastate Purchase of Explosives Coupon ACTION: 30-Day notice. The Department of... and assumptions used; --Enhance the quality, utility, and clarity of the information to be collected... collection. (2) Title of the Form/Collection: Report of Stolen or Lost ATF F 5400.30, Intrastate Purchase of...

  7. Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    DEFF Research Database (Denmark)

    Andersen, Stine Hasselholt; Lykkesfeldt, Jens; Larsen, Jytte Overgaard

    2015-01-01

    Abstract In neuroscience, the optical fractionator technique is frequently used for unbiased cell number estimations. Although unbiased in theory, the practical application of the technique is often biased by the necessity of introducing a guard zone at one side of the disector to counter lost caps...

  8. The aesthetic treatment for anterior teeth with lost crown by endorestoration

    Directory of Open Access Journals (Sweden)

    Nanik Zubaidah

    2009-06-01

    Full Text Available Background: The aesthetic has an important role in social life, especially the anterior teeth. The aesthetic abnormality of anterior teeth i.e. discoloration, malpotition or the anterior teeth with crown damage for more than one third or all part of crown is lost due to caries or other causes, will influence its appearance especially during smile. Purpose: The aim of this case report, therefore, is to show how teeth with clinical crown lost or only the root left still can be treated by endorestoration treatment in order to reconstruct the shape and function of the teeth similar to the original ones. Case: Female 52 years old with the lost crown of anterior teeth. The patient did not want her teeth to be extracted. Case Management: The abnormality of these teeth are still able to be reconstructed by endorestoration i.e. endodontic treatment with post and core insertion in the root canal will increase its retention and recovery by the porcelain crown fused to metal to recover the original formation and aesthetic and thus has the normal refunction. The treatment, it improve the confidence of the patient, and also can function normally. The patient did not feel pain. Ronsenography showed the periapical lesion diminished, the neighbor gingival was going better in both function and color. Conclusion: Endorestoration treatment on the anterior teeth with lost crown could recover the normal function, dental aesthetic and self confidence.

  9. Lost Souls? The Demoralization of Academic Labour in the Measured University

    Science.gov (United States)

    Sutton, Paul

    2017-01-01

    In this conceptual paper, I contend that the soul of academic labour is becoming lost in performativity. Performativity, I explain, is a form of regulation and control that deploys technical rationality and judgements to incentivize and punish academics. Indeed, performativity is central to the culture of measurement within contemporary…

  10. Digging for Lost Rivers in Thailand: Locating and Dating Paleochannels in the Chiang Mai Intermontane Basin

    Science.gov (United States)

    Teo, Elisha A.; Ziegler, Alan D.; Wasson, Robert J.; Morthekai, Paulramasamy

    2017-04-01

    The drainage of the Chiang Mai basin has a dynamic but largely forgotten history. In the late 1980s, an ancient lost city was excavated near the Ping River in Chiang Mai, Thailand. Archaeologists had unearthed Wiang Kum Kam, the former royal capital of the Lanna Civilisation founded in 1286 CE. Former investigations revealed that flood sediments buried the capital and remnants of an abandoned river channel were discovered beneath the surface. This concurs with historical descriptions of the Ping River being on the eastern bank of the capital, despite being presently located on the western bank. The paleochannel drained 500 years ago after diverting west of the ancient city. This switch, an avulsion, coincided with a large flood, which could have triggered and/or caused the avulsion. Local oral histories also recount other Ping avulsions across the basin, but these were not documented. Some of these paleochannels residually remain as unusually sinuous irrigation canals, with historically suggestive names such as the Old Ping and the Small Ping Rivers. Here, the geomorphological evolution of the Ping River is investigated, as a future avulsion in this extensively populated area would be catastrophic. Evidence shows that the drainage of the Chiang Mai basin evolved from a braided system, to an avulsing anastomosing system, to a primarily single channel system. Two-dimensional electrical resistivity tomography and augering detected a large continuous body of fluvial sand 4 m below the surface, across the 10 km distance between the Ping and Kuang Rivers. This sand continues to the depth of at least 30 m and is typical of a braided system. Further augering along paleochannels revealed buried levees that protrude from the braided river deposits to near the surface, separated by fine floodplain sediments. This may have formed as the braided system evolved into an anastomosing system, where distinct channels stabilised and floodplain deposits could develop between channels

  11. Evolution of heteromorphic sex chromosomes in the order Aulopiformes.

    Science.gov (United States)

    Ota, K; Kobayashi, T; Ueno, K; Gojobori, T

    2000-12-23

    The fish order Aulopiformes contains both synchronously hermaphroditic and gonochoristic species. From the cytogenetic viewpoint, few reports show that gonochoristic Aulopiformes have heteromorphic sex chromosomes. Because fish in this order give us a unique opportunity to elucidate the evolution of sex chromosomes, it is important to examine a phylogenetic relationship in Aulopiformes by both molecular evolutionary and cytogenetic methods. Thus, we conducted molecular phylogenetic and cytogenetic studies of six Aulopiform species. Our results suggested that hermaphroditic species were evolutionarily derived from gonochoristic species. It follows that the hermaphroditic species might have lost the heteromorphic sex chromosomes during evolution. Here, we suggest a possibility that heteromorphic sex chromosomes can disappear from the genome, even if they have appeared once in evolution. Taking into account Ohno's hypothesis that heteromorphic sex chromosomes might have emerged from autosomes, we propose the hypothesis that heteromorphic sex chromosomes may have undergone repeated events of appearance and disappearance during the course of fish evolution.

  12. Years of Life Lost Due to External Causes of Death in the Lodz Province, Poland

    Science.gov (United States)

    Pikala, Malgorzata; Bryla, Marek; Bryla, Pawel; Maniecka-Bryla, Irena

    2014-01-01

    Background The aim of the study is the analysis of years of life lost due to external causes of death, particularly due to traffic accidents and suicides. Materials and Methods The study material includes a database containing information gathered from 376,281 death certificates of inhabitants of the Lodz province who died between 1999 and 2010. The Lodz province is characterized by the highest mortality rates in Poland. The SEYLLp (Standard Expected Years of Life Lost per living person) and the SEYLLd (per death) indices were used to determine years of life lost. Joinpoint models were used to analyze time trends. Results In 2010, deaths due to external causes constituted 6.0% of the total number of deaths. The standardized death rate (SDR) due to external causes was 110.0 per 100,000 males and was five times higher than for females (22.0 per 100,000 females). In 2010, the SEYLLp due to external causes was 3746 per 100,000 males and 721 per 100,000 females. Among males, suicides and traffic accidents were the most common causes of death (the values of the SEYLLp were: 1098 years and 887 years per 100,000 people, respectively). Among females, the SEYLLp values were 183 years due to traffic accidents and 143 years due to suicides (per 100,000 people). Conclusions A decrease in the number of years of life lost due to external causes is much higher among females. The authors observe that a growing number of suicides contribute to an increase in the value of the SEYLLp index. This directly contributes to over-mortality of males due to external causes. The analysis of the years of life lost focuses on the social and economic aspects of premature mortality due to external causes. PMID:24810942

  13. The Lost City Hydrothermal Field: A Spectroscopic and Astrobiological Analogue for Nili Fossae, Mars.

    Science.gov (United States)

    Amador, Elena S; Bandfield, Joshua L; Brazelton, William J; Kelley, Deborah

    2017-11-01

    Low-temperature serpentinization is a critical process with respect to Earth's habitability and the Solar System. Exothermic serpentinization reactions commonly produce hydrogen as a direct by-product and typically produce short-chained organic compounds indirectly. Here, we present the spectral and mineralogical variability in rocks from the serpentine-driven Lost City Hydrothermal Field on Earth and the olivine-rich region of Nili Fossae on Mars. Near- and thermal-infrared spectral measurements were made from a suite of Lost City rocks at wavelengths similar to those for instruments collecting measurements of the martian surface. Results from Lost City show a spectrally distinguishable suite of Mg-rich serpentine, Ca carbonates, talc, and amphibole minerals. Aggregated detections of low-grade metamorphic minerals in rocks from Nili Fossae were mapped and yielded a previously undetected serpentine exposure in the region. Direct comparison of the two spectral suites indicates similar mineralogy at both Lost City and in the Noachian (4-3.7 Ga) bedrock of Nili Fossae, Mars. Based on mapping of these spectral phases, the implied mineralogical suite appears to be extensive across the region. These results suggest that serpentinization was once an active process, indicating that water and energy sources were available, as well as a means for prebiotic chemistry during a time period when life was first emerging on Earth. Although the mineralogical assemblages identified on Mars are unlikely to be directly analogous to rocks that underlie the Lost City Hydrothermal Field, related geochemical processes (and associated sources of biologically accessible energy) were once present in the subsurface, making Nili Fossae a compelling candidate for a once-habitable environment on Mars. Key Words: Mars-Habitability-Serpentinization-Analogue. Astrobiology 17, 1138-1160.

  14. Lost opportunity cost of surgical training in the Australian private sector.

    Science.gov (United States)

    Aitken, R James

    2012-03-01

    To meet Australia's future demands, surgical training in the private sector will be required. The aim of this study was to estimate the time and lost opportunity cost of training in the private sector. A literature search identified studies that compared the operation time required by a supervised trainee with a consultant. This time was costed using a business model. In 22 studies (34 operations), the median operation duration of a supervised trainee was 34% longer than the consultant. To complete a private training list in the same time as a consultant list, one major case would have to be dropped. A consultant's average lost opportunity cost was $1186 per list ($106,698 per year). Training in rooms and administration requirements increased this to $155,618 per year. To train 400 trainees in the private sector to college standards would require 54,000 training lists per year. The consultants' national lost opportunity cost would be $137 million per year. The average lost hospital case payment was $5894 per list, or $330 million per year nationally. The total lost opportunity cost of surgical training in the private sector would be about $467 million per year. When trainee salaries, other specialties and indirect expenses are included, the total cost will be substantially greater. It is unlikely that surgeons or hospitals will be prepared to absorb these costs. There needs to be a public debate about the funding implications of surgical training in the private sector. © 2012 The Author. ANZ Journal of Surgery © 2012 Royal Australasian College of Surgeons.

  15. Responses to lost letters about a 2000 General Election amendment to abolish prohibition of interracial marriages in Alabama.

    Science.gov (United States)

    Bridges, F Stephen; Keeton, Kato B; Clark, L Nicholle

    2002-12-01

    A field study using 621 "lost" letters was conducted in the city of Mobile and in small towns in mostly rural Baldwin County, Alabama. Milgram's lost letter technique was validated against the actual votes cast during the November 7, 2000 General Election. The technique was successful as an unobtrusive measure useful for predicting patterns of voting behavior. Rates of return of lost letters "in favor of and opposed to legalizing interracial marriage" agreed with the actual election returns (chi-square "goodness of fit"). Community size seemed associated with return of lost letters.

  16. Measurements of the total energy lost per electron-ion pair lost in low-pressure inductive argon, helium, oxygen and nitrogen discharge

    International Nuclear Information System (INIS)

    Lee, Young-Kwang; Ku, Ju-Hwan; Chung, Chin-Wook

    2011-01-01

    Experimental measurements of the total energy lost per electron-ion pair lost, ε T , were performed in a low-pressure inductive atomic gases (Ar, He) and molecular gases (O 2 , N 2 ) discharge. The value of ε T was determined from a power balance based on the electropositive global (volume-averaged) model. A floating harmonic method was employed to measure ion fluxes and electron temperatures at the discharge wall. In the pressure range 5-50 mTorr, it was found that the measured ε T ranged from about 70 to 150 V for atomic gases, but from about 180 to 1300 V for molecular gases. This difference between atomic and molecular discharge is caused by additional collisional energy losses of molecular gases. For argon discharge, the stepwise ionization effect on ε T was observed at relatively high pressures. For different gases, the measured ε T was evaluated with respect to the electron temperature, and then compared with the calculation results, which were derived from collisional and kinetic energy loss. The measured ε T and their calculations showed reasonable agreement.

  17. THE LOST-CITY DAN LOST-SPACE KARENA PERKEMBANGAN PENGEMBANGAN TATA-RUANG KOTA Kasus Koridor Komersial Jalan Tunjungan Kotamadya Surabaya

    Directory of Open Access Journals (Sweden)

    Benny Poerbantanoe

    1999-01-01

    Full Text Available Every town hss its own architectural performance. And architecture is not merely a physical landscape of buildings in a town,, as seen by the observer, but it has a deeper mening, which displays the art of structures and constructions. It is a sequence of buildings along the course of its history (Aldo Rossi, 1980. A Town is a complete work of art, performed by men of urban knowledge. Tehe concept of a town or urban workmanship arises from time to time as a work of art in multiple variations, together and according to spirit of the time, included its aspects of belief and religion. The urban work of art or urban artefact is always related to location, historical events and the spesific urban look. Generally a town has particular rythm and dynamics, at least it does not remain static. Therefore it is quite right, when we say, that a town represents the course of its history and technology during the period of its existence. But when we scrutinise alongthe historical and visual systems, it turns out that so many physical and sociqal spaces have been altered with regard to their quality and quantity, as result mis management ot the physical and social spaces by less careful urban reformists. they may bring about certain inbalancy in the system, destroying public imagination and memory about the identity and message conceived at the time of their construction. At the this may affect a condition, commonly called the lost space. Surabaya is one of the larger towns in Indonesia, which afrtime possessed a number of urban artefacts and workmanship. One of which is the Tunjungan Street, designed and developed by the Gemeente Administration of the Duutch as comercial corriodor of the town, with all its advantages and shortcomings. In spite of the fact that it has never been touched by the hands of the prominent urban planner Mr. Thomas C. Karsten, who has prepared and worked out the architecture of the bigger towns of the former Netherlands Indies like

  18. How Important is Presenteeism for the Value of Lost Production in Rheumatoid Arthritis?

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Sørensen, Jan; Linde, Louise

    2010-01-01

    Lost production can be due to individuals’ time lost to work (absenteeism), as well as their time at work with reduced productivity because of ill health (presenteeism). A sound methodological framework for the assessment of presenteeism remains to be established but given its significance......, ignoring it would lead to severe underestimations, eg, in cost-of-illness studies. The objective of this study was to assess the empirical significance of absenteeism and presenteeism in terms of production loss using the case of rheumatoid arthritis (RA). Selected modules from the Health and Labor...... Questionnaire were applied in a cross-sectional study of 3,704 patients with RA. The costs of absenteeism and presenteeism were estimated using the Human Capital approach, and the impact of including multipliers adjusting for the productivity effect of a workers’ absence or impaired presenteeism on societal...

  19. The Anomalous Currents In The Front Foils of the JET Lost Alpha Diagnostic KA-2

    International Nuclear Information System (INIS)

    Cecil, F.E.; Kiptily, V.; Salmi, A.; Horton, A.; Fullard, K.; Murari, A.; Darrow, D.; Hill, K.

    2011-01-01

    We have examined the observed currents in the front foils of the JET Faraday cup lost alpha particle diagnostic KA-2. In particular, we have sought to understand the currents during Ohmic plasmas for which the ion flux at the detectors was initially assumed to be negligible. We have considered two sources of this current: plasma ions (both deuterium and impurity) in the vicinity of the detector (including charge exchange neutrals) and photoemission from scattered UV radiation. Based upon modeling and empirical observation, the latter source appears most likely and, moreover, seems to be applicable to the currents in the front foil during ELMy H-mode plasmas. A very thin gold or nickel foil attached to the present detector aperture is proposed as a solution to this problem, and realistic calculations of expected fluxes of lost energetic neutral beam ions during TF ripple experiments are presented as justification of this proposed solution.

  20. [Abortion and the man. Psychological and psychopathological manifestations in the face of lost fatherhood].

    Science.gov (United States)

    Benvenuti, P; Borri, P; Buzzoni, P; Clerici, L; Rossi Monti, M

    1983-01-01

    This study examines the psychological and psychopathological reactions that may appear in a man when his partner aborts. The small amount of literature that exists on the subjects was examined, and several men were, interviewed at the time their partners aborted voluntarely. It turns out that in spite of the man's lack of recognition of any reactions (reinforced by current attitudes and by the scant psychological and medical interest in the subject), there is considerable emotional involvement in the lost parenthood, both for the man and the woman. As revealed by the interviews, this involvement may manifest itself in persecutory or depressive anxiety and psychosomatic symptoms. Moreover, but very rarely, real and typical psychopathological symptoms may appear, such as depression and behavioural disorders. The appearance of these reactions is linked to the problems and conflicts aroused by prospective fatherhood, leading to a comparison between the experiences of fuliwed fatherhood and those of fatherhood lost.

  1. Lost-to-follow-up bias in an occupational mortality analysis: a quantitative consideration

    International Nuclear Information System (INIS)

    Acquavella, J.F.; Tietjen, G.L.; Wilkinson, G.S.

    1982-12-01

    A major problem in occupational cohort studies is how to treat study subjects who are lost to follow-up (LTF). The assumptions made concerning their vital status may affect the results of comparative mortality analyses. The problem was considered within the context of an occupational follow-up study of white male employees at a nuclear facility in Colorado. In this analysis, 568 or 8% of cohort members were LTF. Comparative mortality for the entire cohort was estimated by treating LTF workers as lost at employment termination date, as living at the end-of-study date, and with cumulative mortality simulated between 0% and 100%. Results indicate that simulations of cumulative mortality among employees LTF can be useful in assessing the potential bias caused by LTF mortality assumptions. Further, a general method for assessing LTF bias in occupational analyses is proposed

  2. The Anomalous Currents In The Front Foils of the JET Lost Alpha Diagnostic KA-2

    Energy Technology Data Exchange (ETDEWEB)

    Cecil, F. E.; Kiptily, V.; Salmi, A.; Horton, A.; Fullard, K.; Murari, A.; Darrow, D.; Hill, K.

    2011-05-04

    We have examined the observed currents in the front foils of the JET Faraday cup lost alpha particle diagnostic KA-2. In particular, we have sought to understand the currents during Ohmic plasmas for which the ion flux at the detectors was initially assumed to be negligible. We have considered two sources of this current: plasma ions both deuterium and impurity in the vicinity of the detector including charge exchange neutrals and photoemission from scattered UV radiation. Based upon modeling and empirical observation, the latter source appears most likely and, moreover, seems to be applicable to the currents in the front foil during ELMy H-mode plasmas. A very thin gold or nickel foil attached to the present detector aperture is proposed as a solution to this problem, and realistic calculations of expected fluxes of lost energetic neutral beam ions during TF ripple experiments are presented as justification of this proposed solution.

  3. Effect of pressure in mould on the mould cavity filling in Lost Foam process

    Directory of Open Access Journals (Sweden)

    T. Pacyniak

    2010-10-01

    Full Text Available In this study, the analysis of the influence of the pressure in mould on manufacture process of castings by the Lost Foam method wasintroduced. In particular, numerical simulation results of effect of pressure in mould on pouring rate, gas gap pressure and gas gap sizewere analyzed. For simulating investigations of the Lost Foam process introduced mathematical model of the process was used. In thismodel in detail was described and derived equation relating to the changes of the gas pressure in the gas gap. The mathematical description uses the equation of gas state and the equation of Darcy’s rate of filtration. Presented studies indicated, that with decrease of pressure in mould the pouring rate increased and the gas pressure in gas gap and gas gap size decreased. For pressures in mould from the range of 20÷100 kPa, pouring rates achieved values from 30÷3 cm/s respectively.

  4. Faraday-cup-type lost fast ion detector on Heliotron J

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, S., E-mail: yamamoto.satoshi.6n@kyoto-u.ac.jp; Kobayashi, S.; Nagasaki, K.; Okada, H.; Minami, T.; Kado, S.; Ohshima, S.; Weir, G. M.; Konoshima, S.; Mizuuchi, T. [Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto 611-0011 (Japan); Ogawa, K.; Isobe, M. [National Institute for Fusion Science, National Institutes of Natural Sciences, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); SOKENDAI (The Graduate University for Advanced Studies), 322-6 Oroshi, Toki, Gifu 509-5292 (Japan); Darrow, D. S. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States); Nakamura, Y.; Ohtani, Y. [Graduate School of Energy Science, Kyoto University, Gokasho, Uji, Kyoto 611-0011 (Japan); Kemmochi, N. [National Institute for Fusion Science, National Institutes of Natural Sciences, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan)

    2016-11-15

    A Faraday-cup type lost-fast ion probe (FLIP) has been designed and installed in Heliotron J for the purpose of the studies of interaction between fast ions and MHD instabilities. The FLIP can measure the co-going fast ions whose energy is in the range of 1.7–42.5 keV (proton) and pitch angle of 90{sup ∘}–140{sup ∘}, especially for fast ions having the injection energy of neutral beam injection (NBI). The FLIP successfully measured the re-entering passing ions and trapped lost-fast ions caused by fast-ion-driven energetic particle modes in NBI heated plasmas.

  5. Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.

    Science.gov (United States)

    Tetteh, Paul W; Basak, Onur; Farin, Henner F; Wiebrands, Kay; Kretzschmar, Kai; Begthel, Harry; van den Born, Maaike; Korving, Jeroen; de Sauvage, Frederic; van Es, Johan H; van Oudenaarden, Alexander; Clevers, Hans

    2016-02-04

    Intestinal crypts display robust regeneration upon injury. The relatively rare secretory precursors can replace lost stem cells, but it is unknown if the abundant enterocyte progenitors that express the Alkaline phosphate intestinal (Alpi) gene also have this capacity. We created an Alpi-IRES-CreERT2 (Alpi(CreER)) knockin allele for lineage tracing. Marked clones consist entirely of enterocytes and are all lost from villus tips within days. Genetic fate-mapping of Alpi(+) cells before or during targeted ablation of Lgr5-expressing stem cells generated numerous long-lived crypt-villus "ribbons," indicative of dedifferentiation of enterocyte precursors into Lgr5(+) stems. By single-cell analysis of dedifferentiating enterocytes, we observed the generation of Paneth-like cells and proliferative stem cells. We conclude that the highly proliferative, short-lived enterocyte precursors serve as a large reservoir of potential stem cells during crypt regeneration. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Lost : une « romance » shakespearienne ?

    OpenAIRE

    Hatchuel, Sarah; Laist, Randy

    2016-01-01

    Qu’est-ce qu’une romance shakespearienne ? Comment lire Lost à l’aune de Shakespeare ? Et comment, en retour, lire Shakespeare à l’aune de Lost ? Les quatre pièces dites « tardives » de Shakespeare, Pericles (1608), Cymbeline (1609), Le Conte d’hiver (1610) et La Tempête (1611), ont brouillé la frontière entre les genres en incorporant des épisodes tragiques tout en se terminant dans l’harmonie. Ces pièces ont mis au défi les catégories dramatiques et ont échappé aux définitions simples. Péré...

  7. 27 CFR 25.286 - Claims for remission of tax on beer lost in transit between breweries.

    Science.gov (United States)

    2010-04-01

    ... tax on beer lost in transit between breweries. 25.286 Section 25.286 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Refund or Adjustment of Tax or Relief From Liability § 25.286 Claims for remission of tax on beer lost in transit...

  8. 77 FR 25193 - Notice of Availability of the Draft Environmental Impact Statement for the Lost Creek Uranium In...

    Science.gov (United States)

    2012-04-27

    ...-166318] Notice of Availability of the Draft Environmental Impact Statement for the Lost Creek Uranium In... (EIS) for the Lost Creek Uranium In Situ Recovery (ISR) Project and by this notice is announcing the... subpart 3809 regulations to construct a uranium ore recovery plant, an access road to the site, and a...

  9. 27 CFR 19.41 - Claims on spirits, denatured spirits, articles, or wines lost or destroyed in bond.

    Science.gov (United States)

    2010-04-01

    ..., denatured spirits, articles, or wines lost or destroyed in bond. 19.41 Section 19.41 Alcohol, Tobacco... DISTILLED SPIRITS PLANTS Taxes Claims § 19.41 Claims on spirits, denatured spirits, articles, or wines lost..., relating to the destruction or loss of spirits, denatured spirits, articles, or wines in bond, shall be...

  10. Idabloki unustatud kino : Ülevaade konverentiskogumikust "Via Transversa : Lost Cinema of the Former Eastern Bloc" / Martin Oja

    Index Scriptorium Estoniae

    Oja, Martin, 1978-

    2009-01-01

    2007. a. oktoobris Tallinnas toimunud konverentsi "Via Transversa : Lost Cinema of the Former Eastern Bloc" ettekannetel põhinevast kogumikust: Via Transversa : Lost Cinema of the Former Eastern Bloc / editors Eva Näripea, Andreas Trossek. Tallinn : Eesti Kunstiakadeemia, 2008. (Koht ja paik ; 7)

  11. Mortality and potential life years lost due to external causes: Colombia from 1998 to 2015

    Directory of Open Access Journals (Sweden)

    Alejandra Segura-Cardona

    2018-05-01

    Full Text Available Introduction: The external causes of mortality are constituted as a public health problem which affect young population, have social relevance, are avoidable and their impact is reducible in the long term. Objective: To describe the behavior of mortality due to external causes and the potential years of life lost in the Colombian population from 1998 to 2015. Materials and methods: An analytical study was conducted by using 641,837 death certificates which were classified in four large groups of external mortality: homicide, suicide, traffic accident and other causes. Mortality rates (crude and standardized were calculated with direct method in three periods of time and potential years of life lost, for each group. Results: The risk of dying from external causes was 81.66 per hundred thousand inhabitants, with a decrease of 47.1% and 37.6 potential years of life lost. For homicide, a rate of 47.3 per hundred thousand inhabitants was recorded, with a reduction of 59.3% and 23 potential years of life lost. Traffic accidents recorded a reduction of 30.3% with a rate of 15.7. Suicide documented less reduction in 18 years of age (9.8% and an average rate of 5.1. Conclusion: Deaths caused by external causes are priorities when it comes to raising public policies, mainly for the reduction of homicides that are a reflection of the armed conflict and the crime presented in the country, generating the loss of years of productive life for society. It is necessary to outline the perpetrators to focus and intervene the most affected populations.

  12. Teaching Teenagers with Autism to Answer Cell Phones and Seek Assistance When Lost

    OpenAIRE

    Hoch, Hannah; Taylor, Bridget A; Rodriguez, Angela

    2009-01-01

    Three participants with autism were taught to answer a cell phone and to follow directions to seek assistance when lost in community settings. During baseline, none of the participants answered a cell phone or sought assistance. Following instruction at school and in the community, all participants learned to answer the cell phone and follow instructions to seek assistance from a naïve adult by exchanging a communication card. Generalization probes were conducted in non-training community sit...

  13. The Effect of Units Lost Due to Deterioration in Fuzzy Economic Order Quantity (FEOQ) Model

    OpenAIRE

    M. Pattnaik

    2013-01-01

    For several decades, the Economic Order Quantity (EOQ) model and its variations have received much attention from researchers. Recently, there has been an investigation into an EOQ model incorporating effect of units lost due to deterioration in infinite planning horizon with crisp decision environment. Accounting for holding and ordering cost, as has traditionally been the case of modeling inventory systems in fuzzy environment are investigated which are not precisely known and defined on a ...

  14. How to get lost customers back? : a study of antecedents of relationship revival

    OpenAIRE

    Homburg, Christian; Hoyer, Wayne D.; Stock-Homburg, Ruth

    2006-01-01

    Most research in the field of customer relationship management has focused on keeping existing customers. However, some companies also systematically address lost customers and try to revive these relationships. This facet of customer relationship management has been largely neglected by academic research. Our study provides a theoretical discussion and an empirical analysis of factors driving the success of relationship revival activities. Drawing on equity theory we find that the cust...

  15. Diet Type and Changes in Food Cravings following Weight Loss: Findings from the POUNDS LOST Trial

    OpenAIRE

    Anton, Stephen D.; Gallagher, Jacqueline; Carey, Vincent J.; Laranjo, Nancy; Cheng, Jing; Champagne, Catherine M.; Ryan, Donna H.; McManus, Kathy; Loria, Catherine M.; Bray, George A.; Sacks, Frank M.; Williamson, Donald A.

    2012-01-01

    Few well-controlled trials have evaluated the effects that macronutrient composition has on changes in food cravings during weight loss treatment. The present study, which was part of the POUNDS LOST trial, investigated whether the fat and protein content of four different diets affected changes in specific food cravings in overweight and obese adults. A sample of 811 adults were recruited across two clinical sites, and each participant was randomly assigned to one of four macronutrient presc...

  16. Mortality rate and years of life lost from unintentional injury and suicide in South India

    DEFF Research Database (Denmark)

    Bose, Anuradha; Konradsen, Flemming; John, Jacob

    2006-01-01

    We calculated mortality rates and years of life lost because of unintentional injuries and suicides using community based information obtained prospectively over a 7-year period, from 1998 to 2004, among a rural and peri-urban population of 108,000 in South India. Per 100,000 population the total...... in this study is significantly higher than the figures reflected in available reports for India and is likely due to the under reporting in routine mortality statistics, particularly of suicides....

  17. Modeling Lost-Particle Accelerator Backgrounds in PEP-II Using LPTURTLE

    CERN Document Server

    Fieguth, Theodore; Kozanecki, Witold

    2005-01-01

    Background studies during the design, construction, commissioning, operation and improvement of BaBar and PEP-II have been greatly influenced by results from a program referred to as LPTURTLE (Lost Particle TURTLE a modified version of Decay TURTLE) which was originally conceived for the purpose of studying gas background for SLC. This venerable program is still in use today. We describe its use, capabilities and improvements and refer to current results now being applied to BaBar.

  18. Tranexamic Acid Reduced the Percent of Total Blood Volume Lost During Adolescent Idiopathic Scoliosis Surgery.

    Science.gov (United States)

    Jones, Kristen E; Butler, Elissa K; Barrack, Tara; Ledonio, Charles T; Forte, Mary L; Cohn, Claudia S; Polly, David W

    2017-01-01

    Multilevel posterior spine fusion is associated with significant intraoperative blood loss. Tranexamic acid is an antifibrinolytic agent that reduces intraoperative blood loss. The goal of this study was to compare the percent of total blood volume lost during posterior spinal fusion (PSF) with or without tranexamic acid in patients with adolescent idiopathic scoliosis (AIS). Thirty-six AIS patients underwent PSF in 2011-2014; the last half (n=18) received intraoperative tranexamic acid. We retrieved relevant demographic, hematologic, intraoperative and outcomes information from medical records. The primary outcome was the percent of total blood volume lost, calculated from estimates of intraoperative blood loss (numerator) and estimated total blood volume per patient (denominator, via Nadler's equations). Unadjusted outcomes were compared using standard statistical tests. Tranexamic acid and no-tranexamic acid groups were similar (all p>0.05) in mean age (16.1 vs. 15.2 years), sex (89% vs. 83% female), body mass index (22.2 vs. 20.2 kg/m2), preoperative hemoglobin (13.9 vs. 13.9 g/dl), mean spinal levels fused (10.5 vs. 9.6), osteotomies (1.6 vs. 0.9) and operative duration (6.1 hours, both). The percent of total blood volume lost (TBVL) was significantly lower in the tranexamic acid-treated vs. no-tranexamic acid group (median 8.23% vs. 14.30%, p = 0.032); percent TBVL per level fused was significantly lower with tranexamic acid than without it (1.1% vs. 1.8%, p=0.048). Estimated blood loss (milliliters) was similar across groups. Tranexamic acid significantly reduced the percentage of total blood volume lost versus no tranexamic acid in AIS patients who underwent PSF using a standardized blood loss measure.Level of Evidence: 3. Institutional Review Board status: This medical record chart review (minimal risk) study was approved by the University of Minnesota Institutional Review Board.

  19. Ambient air pollution and years of life lost in Ningbo, China

    Science.gov (United States)

    He, Tianfeng; Yang, Zuyao; Liu, Tao; Shen, Yueping; Fu, Xiaohong; Qian, Xujun; Zhang, Yuelun; Wang, Yong; Xu, Zhiwei; Zhu, Shankuan; Mao, Chen; Xu, Guozhang; Tang, Jinling

    2016-03-01

    To evaluate the burden of air pollution on years of life lost (YLL) in addition to mortality, we conducted a time series analysis based on the data on air pollution, meteorological conditions and 163,704 non-accidental deaths of Ningbo, China, 2009-2013. The mean concentrations of particulate matter with aerodynamic diameter population for both outcomes. These findings clarify the burden of air pollution on YLL and highlight the importance and urgency of air pollution control in China.

  20. NAVFAC Safety performance and the use of best practices to reduce lost workhours and accidents

    OpenAIRE

    Stone, James Treacy.

    1998-01-01

    CIVINS (Civilian Institutions) Thesis document This thesis analyzes the safety performance of several U.S. Naval Facilities Engineering Command (NAVFAC) projects as they compare to the construction industry as a whole and to the Construction Industry Institute (CII) Member companies. Safety success on a construction project is measured by examining the Lost Workday Case Incident Rate (LWCIR), Recordable Incident Rate (RIR), and the Fatality Incident Rate (FIR). This thesis will endeavor to...

  1. Lost and Found, Letters and Methods: Assessing Attitudes toward Chiropractic and Medical Care

    Directory of Open Access Journals (Sweden)

    Hannah Kern

    2010-10-01

    Full Text Available Attitudes toward traditional and chiropractic medicine were compared using Milgram's lost letter technique. A total of 192 letters were placed on the windshields of vehicles in parking lots at six restaurants and department stores in each of four quadrants of a medium-sized, Southeastern city. These letters were addressed to "Admissions" at either a fictitious Institute of Medicine or Institute of Chiropractic Care. Return addresses included either a male or a female name. Thus, those who found a lost letter were faced with the option of returning or not returning a letter from either a male or a female, addressed to an Institute of traditional or non-traditional medicine. After examining previous studies which had used the lost letter technique, numerous methodological improvements were implemented. For example, letters were randomly assigned to potential drop spots for each of 24 study locations (six study locations in each of four city quadrants, and a Latin square design was used to control for possible order effects in the four study conditions that were implemented. Nearly 65% of the letters (124 of 192 were returned. We found: 1 letters addressed to a fictitious Institute of Chiropractic Care were just as likely to be returned as those addressed to a fictitious Institute of Medicine; 2 letters with female return addresses were as likely to be returned as those with male return addresses; 3 there was no interaction between study conditions; 4 based on what was essentially a replication study, a comparison of the pattern of returns using the first and second cycle of lost letters (n = 96 for each cycle revealed an equivalent pattern of no-difference findings. DOI: 10.2458/azu_jmmss.v1i1.78

  2. Cinema advertising and the Sea Witch ‘Lost Island’ film (1965)

    OpenAIRE

    Farmer, Richard

    2016-01-01

    Cinema advertising films have for many decades constituted an important element of British cinema programmes, yet they remain relatively under-researched. This article examines the production, distribution and reception of one such film, a 90-second mini-epic called ‘Lost Island’, which was made in 1965 to promote Sea Witch hair dyes. As well as outlining the technological and experiential aspects of the cinema and cinemagoing that continued to make film an attractive medium for advertisers e...

  3. In search of the "lost capital". A theory for valuation, investment decisions, performance measurement

    OpenAIRE

    Magni, Carlo Alberto

    2007-01-01

    This paper presents a theoretical framework for valuation, investment decisions, and performance measurement based on a nonstandard theory of residual income. It is derived from the notion of "unrecovered" capital, which is here named "lost" capital because it represents the capital foregone by the investors. Its theoretical strength and meaningfulness is shown by deriving it from four main perspectives: financial, microeconomic, axiomatic, accounting. Implications for asset valuation, cap...

  4. Smoking: An independent risk factor for lost productivity in chronic rhinosinusitis.

    Science.gov (United States)

    Campbell, Adam P; Hoehle, Lloyd P; Phillips, Katie M; Caradonna, David S; Gray, Stacey T; Sedaghat, Ahmad R

    2017-08-01

    Chronic rhinosinusitis (CRS) is associated with a significant loss of patient productivity that costs billions of dollars every year. Smoking is associated with worsening sinonasal symptoms, but its effect on lost productivity in CRS patients has yet to be described. Therefore, we sought to determine the association between smoking and productivity in patients with CRS. Prospective cross-sectional cohort study of 140 patients with CRS. Sinonasal symptom severity was measured using the 22-item Sino-Nasal Outcomes Test. Lost productivity was assessed by asking participants how many days of work and/or school they missed in the last 3 months due to CRS. Associations were sought between lost productivity and smoking. Participants missed a mean of 3.0 days (standard deviation = 12.8 days) of work or school due to CRS. Having any history of smoking was associated with 6 days of lost productivity due to CRS (adjusted β = 6.20, 95% confidence interval [CI]: 0.64 to 11.77, P = .031). Although the number of active smokers in our study cohort was very small (N = 6), we performed a univariate association between smoking status, considering former smokers and active smokers separately, and found that active smoking (β = 11.75, 95% CI: 2.11 to 21.40, P = .018) had a much larger impact on CRS-related productivity loss than that experienced by former smokers (β = 4.45, 95% CI: -0.32 to 9.23, P = .070). Smoking (likely driven by active smoking) is independently associated with missed days of work or school in patients with CRS. Further study is needed to determine whether interventions directed at smoking may impact CRS-related productivity loss. 2c Laryngoscope, 127:1742-1745, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  5. Disability-adjusted Life Years Lost to Ischemic Heart Disease in Spain.

    Science.gov (United States)

    Fernández de Larrea-Baz, Nerea; Morant-Ginestar, Consuelo; Catalá-López, Ferrán; Gènova-Maleras, Ricard; Álvarez-Martín, Elena

    2015-11-01

    The health indicator disability-adjusted life years combines the fatal and nonfatal consequences of a disease in a single measure. The aim of this study was to evaluate the burden of ischemic heart disease in 2008 in Spain by calculating disability-adjusted life years. The years of life lost due to premature death were calculated using the ischemic heart disease deaths by age and sex recorded in the Spanish National Institute of Statistics and the life-table in the 2010 Global Burden of Disease study. The years lived with disability, calculated for acute coronary syndrome, stable angina, and ischemic heart failure, used hospital discharge data and information from population studies. Disability weights were taken from the 2010 Global Burden of Disease study. We calculated crude and age standardized rates (European Standard Population). Univariate sensitivity analyses were performed. In 2008, 539 570 disability-adjusted life years were lost due to ischemic heart disease in Spain (crude rate, 11.8/1000 population; standardized, 8.6/1000). Of the total years lost, 96% were due to premature death and 4% due to disability. Among the years lost due to disability, heart failure accounted for 83%, stable angina 15%, and acute coronary syndrome 2%. In the sensitivity analysis, weighting by age was the factor that changed the results to the greatest degree. Ischemic heart disease continues to have a huge impact on the health of our population, mainly because of premature death. The results of this study provide an overall vision of the epidemiologic situation in Spain and could serve as the basis for evaluating interventions targeting the acute and chronic manifestations of cardiac ischemia. Copyright © 2014 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  6. Paradise Lost: The Cost of Removing Tax and Trade Provisions from the Compact of Free Association

    OpenAIRE

    Samuel Rueckert Brazys

    2014-01-01

    Upon implementing the Compact of Free Association between the United States and the Federated States of Micronesia, the US Congress unilaterally stripped tax and trade provisions that would have encouraged investment in the Federated States of Micronesia. I quantify what was lost to the Federated States of Micronesia by arguing that the provisions would have made the Federated States of Micronesia an explicitly sanctioned tax haven through empirical estimates of the impact of tax havens on gr...

  7. Out of Africa: misrepresenting Sudan’s ‘Lost Boys’

    Directory of Open Access Journals (Sweden)

    Brandy Witthoft

    2007-01-01

    Full Text Available The US media has taken an intense interest in the experience of a relatively small group of young males who walked from South Sudan to Ethiopia, spent up to a decade in the Kakuma refugee camp in Kenya and were eventually re-settled in the USA in 2001. What is behind the celebrity status – and the cultural misunderstanding – of those dubbed the ‘Lost Boys’?

  8. Preventive Maintenance Interval Prediction: a Spare Parts Inventory Cost and Lost Earning Based Model

    Directory of Open Access Journals (Sweden)

    O. A. Adebimpe

    2015-06-01

    Full Text Available In this paper, some preventive maintenance parameters in manufacturing firms were identified and used to develop cost based functions in terms of machine preventive maintenance. The proposed cost based model considers system’s reliability, cost of keeping spare parts inventory and lost earnings in deriving optimal maintenance interval. A case of a manufacturing firm in Nigeria was observed and the data was used to evaluate the model.

  9. New insights on .i.Paludotona./i., an insular endemic lagomorph (Mammalia) from the Tusco-Sardinian Palaeoprovince (Italy, Turolian, Late Miocene)

    Czech Academy of Sciences Publication Activity Database

    Angelone, Ch.; Čermák, Stanislav; Rook, L.

    2017-01-01

    Roč. 123, č. 3 (2017), s. 455-473 ISSN 0035-6883 Institutional support: RVO:67985831 Keywords : Paludotona minor n. sp. * Paludotona etruria * taxonomy * evolution * insular endemism * palaeobiogeography * MN11–12 Subject RIV: DB - Geology ; Mineralogy OBOR OECD: Paleontology Impact factor: 0.851, year: 2016 https://riviste.unimi.it/index.php/RIPS/article/view/9082

  10. Deeply-sourced formate fuels sulfate reducers but not methanogens at Lost City hydrothermal field.

    Science.gov (United States)

    Lang, Susan Q; Früh-Green, Gretchen L; Bernasconi, Stefano M; Brazelton, William J; Schrenk, Matthew O; McGonigle, Julia M

    2018-01-15

    Hydrogen produced during water-rock serpentinization reactions can drive the synthesis of organic compounds both biotically and abiotically. We investigated abiotic carbon production and microbial metabolic pathways at the high energy but low diversity serpentinite-hosted Lost City hydrothermal field. Compound-specific 14 C data demonstrates that formate is mantle-derived and abiotic in some locations and has an additional, seawater-derived component in others. Lipids produced by the dominant member of the archaeal community, the Lost City Methanosarcinales, largely lack 14 C, but metagenomic evidence suggests they cannot use formate for methanogenesis. Instead, sulfate-reducing bacteria may be the primary consumers of formate in Lost City chimneys. Paradoxically, the archaeal phylotype that numerically dominates the chimney microbial communities appears ill suited to live in pure hydrothermal fluids without the co-occurrence of organisms that can liberate CO 2 . Considering the lack of dissolved inorganic carbon in such systems, the ability to utilize formate may be a key trait for survival in pristine serpentinite-hosted environments.

  11. Transition of Japanese commercial space: What has been lost from the commercial space?

    Directory of Open Access Journals (Sweden)

    Fujioka Tatsuma

    2016-12-01

    Full Text Available This paper compares the types of two commercial spaces in modern Japan, shopping mall and “traditional” shopping district called Shotengai, from the viewpoint of commercial space as the third space in the city. Particularly in the discourse of commercial spaces in Japan, "shopping district" has been portrayed tied to nostalgia. Therefore, the transition of commercial space is always accompanied by a discourse of the" Lost." However, there is no unified opinion about what's been lost in the process of this transition in fact. In this paper, we extract the social category by considering focus on discourse for both places. As a specific object I use to target the research papers and journal articles in Japan. Because these documents are discussed by distinct main thesis and based on specific data, I adopt these materials. After extraction of social category, through the comparison of the two discourses, I reveal what kind of nature is the "Lost" at the commercial spaces as the third place in the city. I also discuss how this change is related the changes in Japanese social relationship and community.

  12. Occupational injury and illness meet the labor market: lessons from labor economics about lost earnings.

    Science.gov (United States)

    Boden, Leslie I

    2006-09-01

    Recent labor economics studies in the United States and Canada have demonstrated that occupational injuries and illnesses often lead to substantial lost earnings for workers and their families. Other studies have shown substantial long-term lost earnings attributable to large-scale layoffs, where no health impairment has taken place. This article uses evidence from these and other studies of apparently different situations to draw inferences about how managers' actions and public policy choices can affect the costs of occupational injuries and illnesses. Although primary prevention remains the policy of choice, reduction in the impact of workplace injuries and illnesses can decrease the costs of these events and can provide substantial benefits. This article proposes two hypotheses and discusses the evidence for each: (a) Loss of the job held at the onset of illness or injury increases time off work and exacerbates workers' lost earnings. (b) Workers' losses may be substantially reduced by policies that encourage employers to rehire people recovering from or disabled by workplace injuries and illnesses.

  13. Dynamical evolution of cosmic strings

    International Nuclear Information System (INIS)

    Bouchet, F.R.

    1988-01-01

    The author have studied by means of numerical simulations the dynamical evolution of a network of cosmic strings, both in the radiation and matter era. Our basic conclusion is that a scaling solution exists, i.e., the string energy density evolves as t -2 . This means that the process by which long strings dump their energy into closed loops (which can gravitationally radiate away) is efficient enough to prevent the string domination over other forms of energy. This conclusion does not depend on the initial string energy density, nor on the various numerical parameters. On the other hand, the generated spectrum of loop sizes does depend on the value of our numerical lower cutoff (i.e., the minimum length of loop we allow to be chopped off the network). Furthermore, the network evolution is very different from what was assumed before), namely the creation of a few horizon sized loops per horizon volume and per hubble time, which subsequently fragment into about 10 smaller daughter loops. Rather, many tiny loops are directly cut from the network of infinite strings, and it appears that the only fundamental scale (the horizon) has been lost. This is probably because a fundamental ingredient had been overlooked, namely the kinks. These kinks are created in pairs at each intercommutation, and very rapidly, the long strings appear to be very kinky. Thus the number of long strings per horizon is still of the order of a few, but their total length is fairly large. Furthermore, a large number of kinks favors the formation of small loops, and their sizes might well be governed by the kink density along the long strings. Finally, we computed the two-point correlation function of the loops and found significant differences from the work of Turok

  14. Evolution of entomopathogenicity in fungi.

    Science.gov (United States)

    Humber, Richard A

    2008-07-01

    The recent completions of publications presenting the results of a comprehensive study on the fungal phylogeny and a new classification reflecting that phylogeny form a new basis to examine questions about the origins and evolutionary implications of such major habits among fungi as the use of living arthropods or other invertebrates as the main source of nutrients. Because entomopathogenicity appears to have arisen or, indeed, have lost multiple times in many independent lines of fungal evolution, some of the factors that might either define or enable entomopathogenicity are examined. The constant proximity of populations of potential new hosts seem to have been a factor encouraging the acquisition or loss of entomopathogenicity by a very diverse range of fungi, particularly when involving gregarious and immobile host populations of scales, aphids, and cicadas (all in Hemiptera). An underlying theme within the vast complex of pathogenic and parasitic ascomycetes in the Clavicipitaceae (Hypocreales) affecting plants and insects seems to be for interkingdom host-jumping by these fungi from plants to arthropods and then back to the plant or on to fungal hosts. Some genera of Entomophthorales suggest that the associations between fungal pathogens and their insect hosts appear to be shifting away from pathogenicity and towards nonlethal parasitism.

  15. Lost life years due to premature mortality caused by diseases of the respiratory system.

    Science.gov (United States)

    Maniecka-Bryła, Irena; Paciej-Gołębiowska, Paulina; Dziankowska-Zaborszczyk, Elżbieta; Bryła, Marek

    2018-06-04

    In Poland, as in most other European countries, diseases of the respiratory system are the 4th leading cause of mortality; they are responsible for about 8% of all deaths in the European Union (EU) annually. To assess the socio-economic aspects of mortality, it has become increasingly common to apply potential measures rather than conventionally used ratios. The aim of this study was to analyze years of life lost due to premature deaths caused by diseases of the respiratory system in Poland from 1999 to 2013. The study was based on a dataset of 5,606,516 records, obtained from the death certificates of Polish residents who died between 1999 and 2013. The information on deaths caused by diseases of the respiratory system, i.e., coded as J00-J99 according to the International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10), was analyzed. The Standard Expected Years of Life Lost (SEYLL) indicator was used in the study. In the years 1999-2013, the Polish population suffered 280,519 deaths caused by diseases of the respiratory system (4.69% of all deaths). In the period analyzed, a gradual decrease in the standardized death rate was observed - from 46.31 per 100,000 inhabitants in 1999 to 41.02 in 2013. The dominant causes of death were influenza and pneumonia (J09-J18) and chronic lower respiratory diseases (J40-J47). Diseases of the respiratory system were the cause of 4,474,548.92 lost life years. The Standard Expected Years of Life Lost per person (SEYLLp) was 104.72 per 10,000 males and 52.85 per 10,000 females. The Standard Expected Years of Life Lost per death (SEYLLd) for people who died due to diseases of the respiratory system was 17.54 years of life on average for men and 13.65 years on average for women. The use of the SEYLL indicator provided significant information on premature mortality due to diseases of the respiratory system, indicating the fact that they play a large role in the health status of the Polish

  16. Inlet Geomorphology Evolution

    Science.gov (United States)

    2015-04-01

    APR 2015 2. REPORT TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Inlet Geomorphology Evolution 5a. CONTRACT NUMBER 5b...Std Z39-18 Coastal Inlets Research Program Inlet Geomorphology Evolution The Inlet Geomorphology Evolution work unit of the CIRP evaluates

  17. Evolution of plant P-type ATPases

    Directory of Open Access Journals (Sweden)

    Christian N.S. Pedersen

    2012-02-01

    Full Text Available Five organisms having completely sequenced genomes and belonging to all major branches of green plants (Viridiplantae were analyzed with respect to their content of P-type ATPases encoding genes. These were the chlorophytes Ostreococcus tauria and Chlamydomonas reinhardtii, and the streptophytes Physcomitrella patens (a moss, Selaginella moellendorffii (a primitive vascular plant, and Arabidopsis thaliana (a model flowering plant. Each organism contained sequences for all five subfamilies of P-type ATPases. Our analysis demonstrates when specific subgroups of P-type ATPases disappeared in the evolution of Angiosperms. Na/K-pump related P2C ATPases were lost with the evolution of streptophytes whereas Na+ or K+ pumping P2D ATPases and secretory pathway Ca2+-ATPases remained until mosses. An N-terminally located calmodulin binding domain in P2B ATPases can only be detected in pumps from Streptophytae, whereas, like in animals, a C-terminally localized calmodulin binding domain might be present in chlorophyte P2B Ca2+-ATPases. Chlorophyte genomes encode P3A ATPases resembling protist plasma membrane H+-ATPases and a C-terminal regulatory domain is missing. The complete inventory of P-type ATPases in the major branches of Viridiplantae is an important starting point for elucidating the evolution in plants of these important pumps.

  18. Evolution of transcriptional enhancers and animal diversity

    Science.gov (United States)

    Rubinstein, Marcelo; de Souza, Flávio S. J.

    2013-01-01

    Deciphering the genetic bases that drive animal diversity is one of the major challenges of modern biology. Although four decades ago it was proposed that animal evolution was mainly driven by changes in cis-regulatory DNA elements controlling gene expression rather than in protein-coding sequences, only now are powerful bioinformatics and experimental approaches available to accelerate studies into how the evolution of transcriptional enhancers contributes to novel forms and functions. In the introduction to this Theme Issue, we start by defining the general properties of transcriptional enhancers, such as modularity and the coexistence of tight sequence conservation with transcription factor-binding site shuffling as different mechanisms that maintain the enhancer grammar over evolutionary time. We discuss past and current methods used to identify cell-type-specific enhancers and provide examples of how enhancers originate de novo, change and are lost in particular lineages. We then focus in the central part of this Theme Issue on analysing examples of how the molecular evolution of enhancers may change form and function. Throughout this introduction, we present the main findings of the articles, reviews and perspectives contributed to this Theme Issue that together illustrate some of the great advances and current frontiers in the field. PMID:24218630

  19. The evolution of plant-insect mutualisms.

    Science.gov (United States)

    Bronstein, Judith L; Alarcón, Ruben; Geber, Monica

    2006-01-01

    Mutualisms (cooperative interactions between species) have had a central role in the generation and maintenance of life on earth. Insects and plants are involved in diverse forms of mutualism. Here we review evolutionary features of three prominent insect-plant mutualisms: pollination, protection and seed dispersal. We focus on addressing five central phenomena: evolutionary origins and maintenance of mutualism; the evolution of mutualistic traits; the evolution of specialization and generalization; coevolutionary processes; and the existence of cheating. Several features uniting very diverse insect-plant mutualisms are identified and their evolutionary implications are discussed: the involvement of one mobile and one sedentary partner; natural selection on plant rewards; the existence of a continuum from specialization to generalization; and the ubiquity of cheating, particularly on the part of insects. Plant-insect mutualisms have apparently both arisen and been lost repeatedly. Many adaptive hypotheses have been proposed to explain these transitions, and it is unlikely that any one of them dominates across interactions differing so widely in natural history. Evolutionary theory has a potentially important, but as yet largely unfilled, role to play in explaining the origins, maintenance, breakdown and evolution of insect-plant mutualisms.

  20. Growth, inter- and intraspecific variation, palaeobiogeography, taphonomy and systematics of the Cenozoic ghost shrimp Glypturus

    Science.gov (United States)

    Klompmaker, Adiël A.; Hyžný, Matúš; Portell, Roger W.; Kowalewski, Michał

    2015-01-01

    Studies in systematic palaeontology are greatly aided when numerous, well-preserved specimens are available so that quantitative methods can be used to substantiate qualitative observations. This is often not the case for fossil decapod crustaceans due to their relatively low preservation potential. Here, we examined primarily two large collections of the well-preserved ghost shrimp Glypturus from the Holo-Pleistocene of Panama and the late Miocene of Florida. Using descriptive, bivariate, multivariate and geometric morphometric methods, two new species are described based on appendage material: Glypturus panamacanalensis sp. nov. and G. sikesi sp. nov. New characters are identified, and size-related and intraspecific variation are assessed for these taxa and modern G. acanthochirus. Taxonomic placement of single specimens from other localities was confirmed by multivariate methods. Furthermore, Glypturus is revised, especially with regard to Western Atlantic species that inhabited both carbonate and siliciclastic environments. Callianassa anguillensis, C. latidigata, and Neocallichirus? quisquellanus are referred to as Glypturus sp. until more material is available to determine the validity of these species. Diversity within Glypturus may thus be underestimated, thereby also impacting the assessment of phylogenetic relationships. Minor propodi appear under-represented relative to major propodi, suggesting a taphonomic bias. Single specimens of interest include a specimen of G. panamacanalensis sp. nov. exhibiting a peculiar swelling in the fixed finger and another showing damage on the propodal upper margin, suggesting failed predation or antagonistic behaviour. Glypturus is first found in the Oligocene in the Western Atlantic and may have expanded its palaeobiogeographical range since the Miocene. The genus was still present on the Pacific side of the Isthmus of Panama in the Holo-Pleistocene, but is only known from the Western Atlantic today, suggesting a relatively recent extinction on the Pacific side. PMID:26819570

  1. Discovery of the first ichthyosaur from the Jurassic of India: Implications for Gondwanan palaeobiogeography.

    Directory of Open Access Journals (Sweden)

    Guntupalli V R Prasad

    Full Text Available An articulated and partially preserved skeleton of an ichthyosaur was found in the Upper Jurassic (Upper Kimmeridgian Katrol Formation exposed at a site south of the village Lodai in Kachchh district, Gujarat (western India. Here we present a detailed description and inferred taxonomic relationship of the specimen. The present study revealed that the articulated skeleton belongs to the family Ophthalmosauridae. The new discovery from India further improves the depauperate fossil record of ichthyosaurs from the former Gondwanan continents. Based on the preserved length of the axial skeleton and anterior part of the snout and taking into account the missing parts of the skull and postflexural region, it is suggested that the specimen may represent an adult possibly reaching a length of 5.0-5.5 m. The widespread occurrence of ophthalmosaurids in the Upper Jurassic deposits of western Tethys, Madagascar, South America and India points to possible faunal exchanges between the western Tethys and Gondwanan continents through a southern seaway.

  2. The significance of presenteeism for the value of lost production: the case of rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Rikke Søgaard

    2010-07-01

    Full Text Available Rikke Søgaard1, Jan Sørensen1, Louise Linde2, Merete L Hetland2,31CAST – Centre for Applied Health Services Research and Technology Assessment, University of Southern Denmark, Denmark; 2Department of Rheumatology, Hvidovre and Glostrup Hospitals, Denmark; 3The DANBIO registry, Hvidovre and Glostrup Hospitals, DenmarkAbstract: Lost production can be due to individuals’ time lost to work (absenteeism, as well as their time at work with reduced productivity because of ill health (presenteeism. A sound methodological framework for the assessment of presenteeism remains to be established but given its significance, ignoring it would lead to severe underestimations, eg, in cost-of-illness studies. The objective of this study was to assess the empirical significance of absenteeism and presenteeism in terms of production loss using the case of rheumatoid arthritis (RA. Selected modules from the Health and Labor Questionnaire were applied in a cross-sectional study of 3,704 patients with RA. The costs of absenteeism and presenteeism were estimated using the Human Capital approach, and the impact of including multipliers adjusting for the productivity effect of a workers’ absence or impaired presenteeism on societal productivity was demonstrated. RA-related absenteeism over the last 14 days was 22.31 hours (standard deviation [SD], 26.51 with a resulting cost of €473 (SD, 575 and €762 (SD, 926 depending on whether a multiplier was included. Presenteeism was found to affect 7.98 (SD, 3.24 working days over the last 14 days with a resulting cost of €168 (SD, 203 and €203 (SD, 245, again depending on whether a multiplier was included. Overall, this article demonstrates that the value of lost production due to RA could be subject to an almost factor 2 increase if productivity effects of presenteeism and general multipliers are included.Keywords: work limitations, Health and Labor Questionnaire, productivity, production loss

  3. Improving maintenance of lost weight following a commercial liquid meal replacement program: a preliminary study.

    Science.gov (United States)

    Ames, Gretchen E; Patel, Roshni H; McMullen, Jillian S; Thomas, Colleen S; Crook, Julia E; Lynch, Scott A; Lutes, Lesley D

    2014-01-01

    Clinic-based liquid meal replacement (800kcals/day) programs produce substantial weight loss. Nevertheless, long-term maintenance remains a challenge. A limitation of maintenance programs is that they continue to promote large behavior changes that are initially required to induce weight loss which may be unsustainable long-term. The study aims were to conduct a preliminary assessment of the feasibility, acceptability, and effectiveness of a small changes maintenance intervention (SCM) for 30 patients who completed liquid meal replacement program (LMR). The 20-session SCM delivered over 52 weeks offered no preset goals for maintenance behaviors and all changes in behavior were self-selected. Participants had a median BMI of 40.9 kg/m(2) and weight of 111 kg at the start of LMR. At LMR completion, they lost 18% (21 kg) of body weight. The SCM was completed by 22 patients (73%); 19 completers (86%) attended ≥ 17 of 20 sessions with a median satisfaction rating of 9 (on a scale of 1 to 9). Completers were asked to record self-selected maintenance behaviors daily (median 351 days recorded). The most commonly reported daily behaviors were self-weighing, use of meal replacements and step counting. Median percent regain at week 52 was 14% (2.8 kg) of lost weight (range, -42 to 74%), significantly less than a median of 56% (11 kg) percent regain of lost weight (range, -78 to 110%) in a demographically similar historical control group with no maintenance intervention after LMR completion (P<0.001). Thus, SCM holds promise for improving weight maintenance. Future research should compare SCM to standard maintenance programs that promote large program-directed changes. © 2013.

  4. Search methods that people use to find owners of lost pets.

    Science.gov (United States)

    Lord, Linda K; Wittum, Thomas E; Ferketich, Amy K; Funk, Julie A; Rajala-Schultz, Päivi J

    2007-06-15

    To characterize the process by which people who find lost pets search for the owners. Cross-sectional study. Sample Population-188 individuals who found a lost pet in Dayton, Ohio, between March 1 and June 30, 2006. Procedures-Potential participants were identified as a result of contact with a local animal agency or placement of an advertisement in the local newspaper. A telephone survey was conducted to identify methods participants used to find the pets' owners. 156 of 188 (83%) individuals completed the survey. Fifty-nine of the 156 (38%) pets were reunited with their owners; median time to reunification was 2 days (range, 0.5 to 45 days). Only 1 (3%) cat owner was found, compared with 58 (46%) dog owners. Pet owners were found as a result of information provided by an animal agency (25%), placement of a newspaper advertisement (24%), walking the neighborhood (19%), signs in the neighborhood (15%), information on a pet tag (10%), and other methods (7%). Most finders (87%) considered it extremely important to find the owner, yet only 13 (8%) initially surrendered the found pet to an animal agency. The primary reason people did not surrender found pets was fear of euthanasia (57%). Only 97 (62%) individuals were aware they could run a found-pet advertisement in the newspaper at no charge, and only 1 person who was unaware of the no-charge policy placed an advertisement. Veterinarians and shelters can help educate people who find lost pets about methods to search for the pets' owners.

  5. The lost value of groundwater and its influence on environmental decision making.

    Science.gov (United States)

    Paleologos, Evan K

    2008-08-01

    A critical aspect in establishing environmental policies lies in the proper assessment of the value of the resource being affected. Standard risk assessment analyses calculate the cost of pollution as consisting, solely, of the cost to remediate a site. This traditional definition is extended here to include the lost value of groundwater. These concepts and their impact on decision-making analyses are illustrated through the case of municipal waste landfills. Based on data from existing polluting sites, a simple cost-benefit probabilistic analysis is conducted first, which equates, as is the practice, the cost of pollution to that of remediation. This leads rationally to selection of the lowest-protection technology. Using plausible arguments the reduction in value of groundwater from potable high-quality water to irrigation water, which is what is returned after remediation, is argued. The arguments consist of: (a) the ratio of the subsidized prices of drinking to irrigation water reflects the relative value of the use of water; (b) the amount paid for remediation, in each case, represents, at a minimum, the value of the water recovered; and (c) the lost value of groundwater equals the value of drinking water minus the value of irrigation water. Incorporation of this lost value of groundwater is sufficient to drastically alter the conclusions of the decision-making analysis and make the highest level technology the most rational and profitable alternative. The broader point of this article lies in that proper accounting of environmental costs is necessary in order to alter environmental policies and practices.

  6. Waterborne outbreak of gastroenteritis: effects on sick leaves and cost of lost workdays.

    Directory of Open Access Journals (Sweden)

    Jaana I Halonen

    Full Text Available BACKGROUND: In 2007, part of a drinking water distribution system was accidentally contaminated with waste water effluent causing a gastroenteritis outbreak in a Finnish town. We examined the acute and cumulative effects of this incidence on sick leaves among public sector employees residing in the clean and contaminated areas, and the additional costs of lost workdays due to the incidence. METHODS: Daily information on sick leaves of 1789 Finnish Public Sector Study participants was obtained from employers' registers. Global Positioning System-coordinates were used for linking participants to the clean and contaminated areas. Prevalence ratios (PR for weekly sickness absences were calculated using binomial regression analysis. Calculations for the costs were based on prior studies. RESULTS: Among those living in the contaminated areas, the prevalence of participants on sick leave was 3.54 (95% confidence interval (CI 2.97-4.22 times higher on the week following the incidence compared to the reference period. Those living and working in the clean area were basically not affected, the corresponding PR for sick leaves was 1.12, 95% CI 0.73-1.73. No cumulative effects on sick leaves were observed among the exposed. The estimated additional costs of lost workdays due to the incidence were 1.8-2.1 million euros. CONCLUSIONS: The prevalence of sickness absences among public sector employees residing in affected areas increased shortly after drinking water distribution system was contaminated, but no long-term effects were observed. The estimated costs of lost workdays were remarkable, thus, the cost-benefits of better monitoring systems for the water distribution systems should be evaluated.

  7. Paradise Lost: Difference Between Adam and Eve's Lament on Leaving Paradise - a Contrastive Analysis

    OpenAIRE

    Servín, Sara Torres

    2013-01-01

    The difference between Adam and Eve’s lament on leaving Paradise in Milton’s Paradise Lost is striking in its contrastive content and depth. This paper analyzes the difference that exists between the feelings and spiritual attitudes that Adam and Eve express on the occasion when they are informed by the angel Michael that they have to abandon the Garden of Eden. It is a comparison of their lament in order to understand the contrast of the two attitudes that Milton wove in the tapestry that Pa...

  8. Source Security Program in the Philippines: a lost source search experience

    International Nuclear Information System (INIS)

    Romallosa, Kristine M.; Salabit, Maria T.; Caseria, Estrella; Valdezco, Eulinia

    2008-01-01

    The Philippine Nuclear Research Institute (PNRI), the national agency in the licensing and regulations of radioactive materials in the country, is strengthening its capabilities in the security of radioactive sources. Part of this program is the PNRI's participation in the Regional Security of Radioactive Sources (RSRS) Project of the Australian Nuclear Science and Technology Organization (ANSTO). The project has provided equipment and methods training, assistance in the development of PNRI's own training program and support for actual orphan source search activities. On May 2007, a source search for the two lost Cs-137 level gauges of a steel manufacturing company was conducted by the PNRI and ANSTO. The source search are the: a) Development of instrument and source search training for the team, the National Training Workshop on Orphan Source Searches which was organized and conducted as a result of train-the-trainors fellowship under the RSRS project; and b) Planning and implementation of the lost source search activity. The conduct of the actual search on warehouses, product yard, canals, dust storage, steel making building, scrap yards and nearby junk shops of the steel plant took one week. The week-long search did not find the lost sources. However, naturally occurring radioactive materials identified to be Thorium, were found on sands, bricks and sack piles that are stored and/or generally present in the warehouses, yard and steel making building. The search activity had therefore cleared the facility of the lost source and its corresponding hazards. The NORM found present in the plant's premises on the other hand brought the attention of the management of the needed measures to ensure safety of the staff from possible hazards of these materials. Currently, the course syllabus that was developed is continuously enhanced to accommodate the training needs of the PNRI staff particularly for the emergency response and preparedness. This component of the source

  9. Cancer incidence in parents who lost a child: a nationwide study in Denmark

    DEFF Research Database (Denmark)

    Li, Jiong; Johansen, Christoffer; Hansen, Dorthe

    2002-01-01

    BACKGROUND: It has been debated whether psychological stress causes cancer, but the scientific evidence remains contradictory. The objective of this study was to investigate whether the death of a child is related to cancer risk in bereaved parents. METHODS: The authors undertook a follow-up study...... based on national registers. All 21,062 parents who lost a child from 1980 to 1996 were recruited for the exposed cohort together with 293,745 randomly selected, unexposed parents. Cox proportional hazards regression models were used to evaluate the relative risk of cancer incidence up to 18 years after......-induced adverse life styles....

  10. Newly Discovered Documents Help to Reconstruct the Purchase of a Lost Princely Wardrobe

    DEFF Research Database (Denmark)

    Thepaut-Cabasset, Corinne

    2015-01-01

    Passports issued for shipments made to Bavaria between 1680 and 1687 represent an exceptional case study, in which we can envisage the reconstruction of a lost 17th centurywardrobe, sent from Paris to Munich. It helps also to learn about the process and the actors who were creating and activating...... fashion business at that time. This short essay aims to demonstrate how important the research in archives enables dress historians to discover new patterns of knowledge to build the history of Ancien Regime clothing culture....

  11. Love’s Labour’s Lost and Much Ado About Nothing: An Early Dipt

    OpenAIRE

    Chiari, Sophie

    2016-01-01

    In his Palladis Tamia published in 1598, Francis Meres gave a list of popular plays, already a fairly long one, written by a young playwright aged 34, William Shakespeare. In Meres’s inventory, an intriguing, unknown play called Love’s Labour’s Won is paired with Love’s Labour’s Lost, a mention which has so far remained a complete mystery. This paper aims at reconsidering the hypothesis according to which Much Ado About Nothing might be the comedy designated under the title of Love’s Labour’s...

  12. Palmyra as it Once Was: 3d Virtual Reconstruction and Visualization of AN Irreplacable Lost Treasure

    Science.gov (United States)

    Denker, A.

    2017-05-01

    Palmyra was a mosaic which was composed through its colourful past, by Assyrians, Parthians, Greeks and Romans. For centuries, the spectacular ruins and impressive panorama of the antique city used to captivate and inspire the visitors as the witnesses of its illustrious history. As a grim consequence of the horrific conflict that engulfed Syria, since May 2015 they are no more to be seen. Palmyra has been purposely targeted and obliterated, the ruins have been reduced to rubble. The immense beauty and rich heritage of Palmyra which has been lost forever is reconstructed here as it was once was, at the top of its glory, with the hope of preserving its memory.

  13. Initial Results from the Lost Alpha Diagnostics on Joint European Torus

    Energy Technology Data Exchange (ETDEWEB)

    Darrow, Doug; Cecil, Ed; Ellis, Bob; Fullard, Keith; Hill, Ken; Horton, Alan; Kiptily, Vasily; Pedrick, Les; Reich, Matthias

    2007-07-25

    Two devices have been installed in the Joint European Torus (JET) vacuum vessel near the plasma boundary to investigate the loss of energetic ions and fusion products in general and alpha particles in particular during the upcoming JET experiments. These devices are (i) a set of multichannel thin foil Faraday collectors, and (ii) a well collimated scintillator which is optically connected to a charge-coupled device. Initial results, including the radial energy and poloidal dependence of lost ions from hydrogen and deuterium plasmas during the 2005–06 JET restart campaign, will be presented.

  14. Value of Lost Load: An Efficient Economic Indicator for Power Supply Security? A Literature Review

    Energy Technology Data Exchange (ETDEWEB)

    Schröder, Thomas, E-mail: t.schroeder@fz-juelich.de; Kuckshinrichs, Wilhelm [Institute of Energy and Climate Research – Systems Analysis and Technology Evaluation (IEK-STE), Forschungszentrum Jülich GmbH, Jülich (Germany)

    2015-12-24

    Security of electricity supply has become a fundamental requirement for well-functioning modern societies. Because of its central position in all sections of society, the present paper considers the economic consequences of a power supply interruption. The value of lost load (VoLL) is a monetary indicator expressing the costs associated with an interruption of electricity supply. This paper reviews different methods for calculating VoLL, provides an overview of recently published studies, and presents suggestions to increase the explanatory power and international comparability of VoLL.

  15. [An Epistemological Analysis of] Predestination and Free-Will in John Milton’s Paradise Lost

    OpenAIRE

    Sayyed Vahid Abtahi

    2014-01-01

    Paradise Lost by John Milton is one of the most important literary works of the seventeenth century. In this epic in verse Milton, by displaying a portrait that combines Greek Mythology and Christian teachings, seeks to elucidate Divine Providence and man’s relation with God’s decree. He puts together Divine will-power and human determination to make the meaning understood of the Man’s Fall. Milton first adhered to Calvin’s school with regard to determinism and free will but afterward he turn...

  16. L'Innocenza Perduta (Lost Innocence: Conserving a Carrara Marble Statue

    Directory of Open Access Journals (Sweden)

    Chris Cleere

    1997-05-01

    Full Text Available This paper describes the conservation of 'L'Innocenza Perduta (Lost Innocence', a marble statue by the Florentine sculptor Emilio Santarelli. As the statue is on open display at University College London and is accessible to the public, it has been vulnerable to destructive elements, including airborne pollutants and vandalism. Cleaning was done by steam and poultice. However, during the cleaning process it became clear that the capital and plinth required more complicated conservation treatments due to considerable cracking of the stone.

  17. The lost archive, the myth of philology, and the study of the Qur’an

    OpenAIRE

    Marx, Michael

    2009-01-01

    A reaction to the article „The Lost Archive“, The Wall Street Journal 12.1.2008, page 1 (US edition) http://online.wsj.com/article/SB120008793352784631.html The belief in the myth that old manuscripts should be mysterious and powerful is part and parcel of the age of Modernity. That such expectations were operative in the discussion on the Qumran fragments is still remembered, and more recently the Da Vinci Code, in itself a quite shallow story, sold extremely well. The fact that the Wall Str...

  18. Colonial waterbird predation on Lost River and Shortnose suckers in the Upper Klamath Basin

    Science.gov (United States)

    Evans, Allen F.; Hewitt, David A.; Payton, Quinn; Cramer, Bradley M.; Collis, Ken; Roby, Daniel D.

    2016-01-01

    We evaluated predation on Lost River Suckers Deltistes luxatus and Shortnose Suckers Chasmistes brevirostris by American white pelicans Pelecanus erythrorhynchos and double-crested cormorants Phalacrocorax auritus nesting at mixed-species colonies in the Upper Klamath Basin of Oregon and California during 2009–2014. Predation was evaluated by recovering (detecting) PIT tags from tagged fish on bird colonies and calculating minimum predation rates, as the percentage of available suckers consumed, adjusted for PIT tag detection probabilities but not deposition probabilities (i.e., probability an egested tag was deposited on- or off-colony). Results indicate that impacts of avian predation varied by sucker species, age-class (adult, juvenile), bird colony location, and year, demonstrating dynamic predator–prey interactions. Tagged suckers ranging in size from 72 to 730 mm were susceptible to cormorant or pelican predation; all but the largest Lost River Suckers were susceptible to bird predation. Minimum predation rate estimates ranged annually from <0.1% to 4.6% of the available PIT-tagged Lost River Suckers and from <0.1% to 4.2% of the available Shortnose Suckers, and predation rates were consistently higher on suckers in Clear Lake Reservoir, California, than on suckers in Upper Klamath Lake, Oregon. There was evidence that bird predation on juvenile suckers (species unknown) in Upper Klamath Lake was higher than on adult suckers in Upper Klamath Lake, where minimum predation rates ranged annually from 5.7% to 8.4% of available juveniles. Results suggest that avian predation is a factor limiting the recovery of populations of Lost River and Shortnose suckers, particularly juvenile suckers in Upper Klamath Lake and adult suckers in Clear Lake Reservoir. Additional research is needed to measure predator-specific PIT tag deposition probabilities (which, based on other published studies, could increase predation rates presented herein by a factor of roughly 2

  19. Search for lost or orphan radioactive sources based on NaI gamma spectrometry

    International Nuclear Information System (INIS)

    Aage, H.K.; Korsbech, U.

    2003-01-01

    Within recent decades many radioactive sources have been lost, stolen, or abandoned, and some have caused contamination or irradiation of people. Therefore reliable methods for source recovery are needed. The use of car borne NaI(Tl) detectors is discussed. Standard processing of spectra in general can disclose strong and medium level signals from manmade nuclides. But methods for detecting low level signals from weak, distant or shielded sources can be improved. New methods for source detection and identification based on noise adjusted singular value decomposition and on area specific stripping of spectra are presented

  20. Exit points, on plasma, of lost fast ions during NBI in TJ-II

    International Nuclear Information System (INIS)

    Guasp, J.

    1995-09-01

    The distribution of the exit points, on plasma border, for the lost fast ions during tangential balanced NBI in TJ-II helical axis Stellarator is theoretically analysed, as well for direct as for delayed losses. The link between the position of those exit points and the corresponding at birth, orbits and drifts is analysed also, it is shown that such relation is rather independent of beam energy and plasma density and is mainly related to the magnetic configuration characteristics. This study is a needed intermediate step to the analysis of impacts of those ions on the vacuum vessel of TJ-II

  1. Alegorias do comportamento Pós-Atentados de 11 de Setembro de 2001, em Lost

    Directory of Open Access Journals (Sweden)

    Glauco Madeira de Toledo

    2010-10-01

    Full Text Available Este texto pretende mostrar que o seriado Lost começa com um storyline que envolve uma alegoria das reações das pessoas aos atentados de 11 de setembro de 2001, nos EUA, por meio das reações dos personagens aos resultados do acidente na ilha. Para este trabalho, foram estudados os quatro primeiros episódios da primeira temporada da série, incluindo o episódio piloto como dois episódios distintos, seguidos por Tabula Rasa e Walkabout.

  2. Drilling fluids and lost circulation in hot-dry-rock geothermal wells at Fenton Hill

    Energy Technology Data Exchange (ETDEWEB)

    Nuckols, E.B.; Miles, D.; Laney, R.; Polk, G.; Friddle, H.; Simpson, G.

    1981-01-01

    Geothermal hot dry rock drilling at Fenton Hill in northern New Mexico encountered problems of catastrophic lost circulation in cavernous areas of limestones in the Sandia Formation, severe corrosion due to temperatures of up to 320/sup 0/C, and torque problems caused by 35/sup 0/ hole angle and the abrasiveness of Precambrian crystalline rock. The use of polymeric flocculated bentonite fluid, clear water, fibrous material, dry drilling, oxygen scavengers, a biodegradable lubricant mixture of modified triglicerides and alcohol, and maintenance of a high pH, were some of the approaches taken toward solving these problems.

  3. Initial Results from the Lost Alpha Diagnostics on Joint European Torus

    International Nuclear Information System (INIS)

    Darrow, Doug; Baeumel, Stefan; Cecil, Ed; Ellis, Bob; Fullard, Keith; Hill, Ken; Horton, Alan; Kiptily, Vasily; Pedrick, Les; Reich, Matthias; Werner, Andreas

    2007-01-01

    Two devices have been installed in the Joint European Torus (JET) vacuum vessel near the plasma boundary to investigate the loss of energetic ions and fusion products in general and alpha particles in particular during the upcoming JET experiments. These devices are (i) a set of multichannel thin foil Faraday collectors, and (ii) a well collimated scintillator which is optically connected to a charge-coupled device. Initial results, including the radial energy and poloidal dependence of lost ions from hydrogen and deuterium plasmas during the 2005-06 JET restart campaign, will be presented.

  4. Exit points, on plasma, of lost fast ions during NBI in TJ-II

    International Nuclear Information System (INIS)

    Guasp, J.

    1995-01-01

    The distribution of the exit points, on plasma border, for the lost fast ions during tangential balanced NBI in TJ-II helical axis Stellarator is theoretically analysed, as well for direct as for delayed losses. The link between, the position of those exit points and the corresponding at birth, orbits and drifts is analysed also. It is shown that such relation is rather independent of beam energy and plasma density and is mainly related to the magnetic configuration characteristics. This study is a needed intermediate step to the analysis of impacts of those ions on the vacuum vessel of TJ-II. (Author) 2 refs

  5. Cause-specific life-years lost in people with mental disorders

    DEFF Research Database (Denmark)

    Erlangsen, Annette; Andersen, Per Kragh; Toender, Anita

    2017-01-01

    mortality due to medical diseases and disorders among people with mental disorders emphasises the need for future interventions to address these aspects as well as the continued high shares of excess mortality due to alcohol misuse, suicide, and accidents. FUNDING: The Lundbeck Foundation Initiative...... diseases (men: 1·2; women: 0·3), and respiratory diseases (men: 0·3; women: 0·2), and a decrease for suicide (men: -0·7; women: -0·5) and accidents (men: -0·9; women: -0·5). INTERPRETATION: By applying a novel approach, more precise estimates of life-years lost were obtained. The increase in excess...

  6. Summary of the Big Lost River fish study on the Idaho National Engineering Laboratory Site

    International Nuclear Information System (INIS)

    Overton, C.K.; Johnson, D.W.

    1978-01-01

    Winter fish mortality and fish migration in the Big Lost River were related to natural phenomenon and man-created impacts. Low winter flows resulted in a reduction in habitat and increased rainbow trout mortality. Man-altered flows stimulated movement and created deleterious conditions. Migratory patterns were related to water discharge and temperature. A food habit study of three sympatric salmonid fishes was undertaken during a low water period. The ratio of food items differed between the three species. Flesh of salmonid fishes from within the INEL Site boundary was monitored for three years for radionuclides. Only one trout contained Cs-137 concentrations above the minimum detection limits

  7. Endothelial glycocalyx on brain endothelial cells is lost in experimental cerebral malaria

    DEFF Research Database (Denmark)

    Hempel, Casper; Hyttel, Poul; Kurtzhals, Jørgen Al

    2014-01-01

    We hypothesized that the glycocalyx, which is important for endothelial integrity, is lost in severe malaria. C57BL/6 mice were infected with Plasmodium berghei ANKA, resulting in cerebral malaria, or P. chabaudi AS, resulting in uncomplicated malaria. We visualized the glycocalyx with transmission...... electron microscopy and measured circulating glycosaminoglycans by dot blot and ELISA. The glycocalyx was degraded in brain vasculature in cerebral and to a lesser degree uncomplicated malaria. It was affected on both intact and apoptotic endothelial cells. Circulating glycosaminoglycan levels suggested...

  8. The digital evolution of occupy wall street.

    Science.gov (United States)

    Conover, Michael D; Ferrara, Emilio; Menczer, Filippo; Flammini, Alessandro

    2013-01-01

    We examine the temporal evolution of digital communication activity relating to the American anti-capitalist movement Occupy Wall Street. Using a high-volume sample from the microblogging site Twitter, we investigate changes in Occupy participant engagement, interests, and social connectivity over a fifteen month period starting three months prior to the movement's first protest action. The results of this analysis indicate that, on Twitter, the Occupy movement tended to elicit participation from a set of highly interconnected users with pre-existing interests in domestic politics and foreign social movements. These users, while highly vocal in the months immediately following the birth of the movement, appear to have lost interest in Occupy related communication over the remainder of the study period.

  9. The digital evolution of occupy wall street.

    Directory of Open Access Journals (Sweden)

    Michael D Conover

    Full Text Available We examine the temporal evolution of digital communication activity relating to the American anti-capitalist movement Occupy Wall Street. Using a high-volume sample from the microblogging site Twitter, we investigate changes in Occupy participant engagement, interests, and social connectivity over a fifteen month period starting three months prior to the movement's first protest action. The results of this analysis indicate that, on Twitter, the Occupy movement tended to elicit participation from a set of highly interconnected users with pre-existing interests in domestic politics and foreign social movements. These users, while highly vocal in the months immediately following the birth of the movement, appear to have lost interest in Occupy related communication over the remainder of the study period.

  10. [Structure and evolution of the eukaryotic FANCJ-like proteins].

    Science.gov (United States)

    Wuhe, Jike; Zefeng, Wu; Sanhong, Fan; Xuguang, Xi

    2015-02-01

    The FANCJ-like protein family is a class of ATP-dependent helicases that can catalytically unwind duplex DNA along the 5'-3' direction. It is involved in the processes of DNA damage repair, homologous recombination and G-quadruplex DNA unwinding, and plays a critical role in maintaining genome integrity. In this study, we systemically analyzed FNACJ-like proteins from 47 eukaryotic species and discussed their sequences diversity, origin and evolution, motif organization patterns and spatial structure differences. Four members of FNACJ-like proteins, including XPD, CHL1, RTEL1 and FANCJ, were found in eukaryotes, but some of them were seriously deficient in most fungi and some insects. For example, the Zygomycota fungi lost RTEL1, Basidiomycota and Ascomycota fungi lost RTEL1 and FANCJ, and Diptera insect lost FANCJ. FANCJ-like proteins contain canonical motor domains HD1 and HD2, and the HD1 domain further integrates with three unique domains Fe-S, Arch and Extra-D. Fe-S and Arch domains are relatively conservative in all members of the family, but the Extra-D domain is lost in XPD and differs from one another in rest members. There are 7, 10 and 2 specific motifs found from the three unique domains respectively, while 5 and 12 specific motifs are found from HD1 and HD2 domains except the conserved motifs reported previously. By analyzing the arrangement pattern of these specific motifs, we found that RTEL1 and FANCJ are more closer and share two specific motifs Vb2 and Vc in HD2 domain, which are likely related with their G-quadruplex DNA unwinding activity. The evidence of evolution showed that FACNJ-like proteins were originated from a helicase, which has a HD1 domain inserted by extra Fe-S domain and Arch domain. By three continuous gene duplication events and followed specialization, eukaryotes finally possessed the current four members of FANCJ-like proteins.

  11. 76 FR 37160 - Notice of Availability of Final Supplemental Environmental Impact Statement for the Lost Creek In...

    Science.gov (United States)

    2011-06-24

    ... assessed the environmental impacts from the construction, operation, aquifer restoration, and..., operate, conduct aquifer restoration, and decommission an ISR facility at Lost Creek. Alternatives that were considered, but were eliminated from detailed analysis, included conventional mining and milling...

  12. Asymmetric evolution and domestication in allotetraploid cotton (Gossypium hirsutum L.

    Directory of Open Access Journals (Sweden)

    Lei Fang

    2017-04-01

    Full Text Available Polyploidy plays a major role in genome evolution, which corresponds to environmental changes over millions of years. The mechanisms of genome evolution, particularly during the process of domestication, are of broad interest in the fields of plant science and crop breeding. Upland cotton is derived from the hybridization and polyploidization of its ancient A and D diploid ancestors. As a result, cotton is a model for polyploid genome evolution and crop domestication. To explore the genomic mysteries of allopolyploid cotton, we investigated asymmetric evolution and domestication in the A and D subgenomes. Interestingly, more structural rearrangements have been characterized in the A subgenome than in the D subgenome. Correspondingly, more transposable elements, a greater number of lost and disrupted genes, and faster evolution have been identified in the A subgenome. In contrast, the centromeric retroelement (RT-domain related sequence of tetraploid cotton derived from the D subgenome progenitor was found to have invaded the A subgenome centromeres after allotetrapolyploid formation. Although there is no genome-wide expression bias between the subgenomes, as with expression-level alterations, gene expression bias of homoeologous gene pairs is widespread and varies from tissue to tissue. Further, there are more positively selected genes for fiber yield and quality in the A subgenome and more for stress tolerance in the D subgenome, indicating asymmetric domestication. This review highlights the asymmetric subgenomic evolution and domestication of allotetraploid cotton, providing valuable genomic resources for cotton research and enhancing our understanding of the basis of many other allopolyploids.

  13. The Bourne Tragedy:
    Lost Subjects of the Bioconvergent Age

    Directory of Open Access Journals (Sweden)

    Debbie Epstein

    2011-10-01

    Full Text Available This paper examines the Bourne trilogy to explore several characteristics of what we term the bioconvergent age. First, we consider the imagined and actual interfaces of bioconvergence—of body, gadgetry, and electronic communications. We explore the ways in which the bioconvergent tendencies represented in and by Bourne reflect and cultivate a cultural unconscious deeply seduced by and imbricated in surveillant governmentality. Second, we consider the ways in which the trilogy achieves its effects through the deployment of both hyperrealism and verisimilitude. In this context, we explore the filmic interpellation of audiences into a fantasy of omnipotence and omni-science, on the one hand, and the underlying phantasy of a zero-sum world that uncouples morality from affect, on the other. Thus, we consider the ways in which Bourne articulates two interlinked phenomena—a distinctively American romance with the sociopathic/heroic subject and a paranoid, dystopic world that is and seems seductively real. Our third theme is the Bourne journey through an obsessional spiral of paranoia, action, and reaction. Here we explore the trilogy as a social description of the expulsive and retentive tendencies of the bioconvergent age, where the demand for instantaneity drives out all other considerations (morality, reason, connection and where the lost subject, in his interminable quest for himself, remains lost.

  14. Lost Mountain: a year in the vanishing wilderness; radical strip mining and the devastation of Appalachia

    Energy Technology Data Exchange (ETDEWEB)

    Reece, E.

    2007-02-15

    The mountains of Appalachia are home to one of the great forests of the world - they predate the Ice Age and scientists refer to them as the 'rainforests' of North America for their remarkable density and species diversity. These mountains also hold the mother lode of American coal, and the coal mining industry has long been the economic backbone for families in a region hard-pressed for other job opportunities. But recently, a new type of mining has been introduced -'radical strip mining', aka 'mountaintop removal'- in which a team employing no more than ten men and some heavy machinery literally blast off the top of a mountain, dump it in the valley below, and scoop out the coal. Erik Reece chronicles the year he spent witnessing the systematic decimation of a single mountain, aptly named 'Lost Mountain'. A native Kentuckian and the son of a coal worker, Reece makes it clear that strip mining is neither a local concern nor a radical contention, but a mainstream crisis that encompasses every hot-button issue - from corporate hubris and government neglect, to class conflict and poisoned groundwater, to irrevocable species extinction and landscape destruction. Published excerpts of Lost Mountain are already driving headlines and legislative action in Kentucky.

  15. Exploring functions of the lost seeking devices for people with dementia.

    Science.gov (United States)

    Chen, Yung-Ching; Leung, Cherng-Yee

    2012-01-01

    This paper utilized a user-centered design approach as the foundation for technology in dementia care in order to improve the quality of telemedicine service. A status-quo analysis and questionnaire survey were conducted to explore the actual needs of the elders in using the lost seeking devices and the problems they encountered. In total, 37 caregivers for people with dementia were surveyed (20 female, 17 male, M = 50.08, SD = 15.47). The dementia-patients: 16 are male, 21 female (M = 72.75, SD = 10.23). Through analysis and induction, 3 problems were identified: poor information transmission, low user acceptance, individual material security anxiety. 2-4 improvement proposals are suggested for each problem. Most care-givers hope technological products would increase the efficiency and safety, but they also think it's too expensive and lack of computer skills. This result demonstrates the choice of seeking methods depends on the education level of the caregivers and most of them are elders. The concern of data leakage is also related to today's fraud issue, which may be the reason limiting the promotion of electronic products and biometrics. Further research is required, suggesting researchers should pursue improvements in lost seeking design devices in dementia for caregivers.

  16. DIACHRONIC RECONSTRUCTION OF LOST CULTURAL HERITAGE SITES. STUDY CASE OF THE MEDIEVAL WALL OF AVILA (SPAIN

    Directory of Open Access Journals (Sweden)

    P. Rodríguez-Gonzálvez

    2018-05-01

    Full Text Available The integration of the fourth dimension into the geospatial data allows to generate a diachronic model of Cultural Heritage (CH assets, namely, a set of 3D models to represent it in various historical phases. This kind of reconstruction pursues a better understanding of the CH site/scenario, enriching the historical hypotheses as well as contributing to the conservation and decisionmaking process. Although the new geotechnologies have reduced the amount of fieldwork, the generation of 4D model implies the interpretation of heterogeneous historical information sources and their integration. However, this situation could reach a critical point when the study elements are no longer present. Their reconstruction will allow the digital preservation and maintenance of our culture. The main challenge is to harmonize the different historical and archaeological data sources available in relation with the current remains, to recover the lost CH assets with a high degree of reliability. This manuscript aims to examine the study case of a diachronic reconstruction by means of the use of the geotechnology Mobile Laser System (MLS and reverse engineering techniques for a lost urban CH element, the citadel or Alcázar Gate of Ávila. Within this aim, the derived product is evaluated in terms of the achieved accuracy to assess its suitability on the basis of constructive interpretations required to integrate the historical sources in relation to current remains and the surrounding.

  17. Replication of specifically microstructured surfaces in A356-alloy via lost wax investment casting

    International Nuclear Information System (INIS)

    Ivanov, Todor; Bührig-Polaczek, Andreas; Vroomen, Uwe; Hartmann, Claudia; Holtkamp, Jens; Gillner, Arnold; Bobzin, Kirsten; Bagcivan, Nazlim; Theiss, Sebastian

    2011-01-01

    A common way of realizing microstructural features on metallic surfaces is to generate the designated pattern on each single part by means of microstructuring technologies such as e.g. laser ablation, electric discharge machining or micromilling. The disadvantage of these process chains is the limited productivity due to the additional processing of each part. The approach of this work is to replicate microstructured surfaces from a master pattern via lost wax investment casting in order to reach a higher productivity. We show that microholes of different sizes ( 15–22 µm at depths of 6–14 µm) can be replicated in AlSi7Mg-alloy from a laser-structured master pattern via investment casting. However, some loss of molding accuracy during the multi-stage molding process occurs. Approximately 50% of the original microfeature's heights are lost during the wax injection step. In the following process step of manufacturing a gypsum-bonded mold, a further loss in the surface quality of the microfeatures can be observed. In the final process step of casting the aluminum melt, the microfeatures are filled without any loss of molding accuracy and replicate the surface quality of the gypsum mold. The contact angle measurements of ultrapure water on the cast surfaces show a decrease in wettability on the microstructured regions (75°) compared to the unstructured region (60°)

  18. The Effect of Units Lost Due to Deterioration in Fuzzy Economic Order Quantity (FEOQ Model

    Directory of Open Access Journals (Sweden)

    M. Pattnaik

    2013-07-01

    Full Text Available For several decades, the Economic Order Quantity (EOQ model and its variations have received much attention from researchers. Recently, there has been an investigation into an EOQ model incorporating effect of units lost due to deterioration in infinite planning horizon with crisp decision environment. Accounting for holding and ordering cost, as has traditionally been the case of modeling inventory systems in fuzzy environment are investigated which are not precisely known and defined on a bounded interval of real numbers. The question is how reliable are the EOQ models when items stocked deteriorate one time. This paper introduces Fuzzy Economic Order Quantity (FEOQ model in which it assumes that units lost due to deterioration is included in the objective function to properly model the problem in finite planning horizon. The numerical analysis shows that an appropriate fuzzy policy can benefit the retailer and that is significant, especially for deteriorating items is shown to be superior to that of crisp decision making. A computational algorithm using LINGO 13.0 and MATLAB (R2009a software are developed to find the optimal solution. Sensitivity analysis of the optimal solution is also studied and managerial insights are drawn which shows the influence of key model parameters.

  19. The migraine ACE model: evaluating the impact on time lost and medical resource Use.

    Science.gov (United States)

    Caro, J J; Caro, G; Getsios, D; Raggio, G; Burrows, M; Black, L

    2000-04-01

    To describe the Migraine Adaptive Cost-Effectiveness Model in the context of an analysis of a simulated population of Canadian patients with migraine. The high prevalence of migraine and its substantial impact on patients' ability to function normally present a significant economic burden to society. In light of the recent availability of improved pharmaceutical treatments, a model was developed to assess their economic impact. The Migraine Adaptive Cost-Effectiveness Model incorporates the costs of time lost from both work and nonwork activities, as well as medical resource and medication use. Using Monte Carlo techniques, the model simulates the experience of a population of patients with migraine over the course of 1 year. As an example, analyses of a Canadian population were carried out using data from a multinational trial, surveys, national statistics, and the available literature. Using customary therapy, mean productivity losses (amounting to 84 hours of paid work time, 48 hours of unpaid work time, and 113 hours of leisure time lost) were estimated to cost $1949 (in 1997 Canadian dollars) per patient, with medical expenditures adding an average of $280 to the cost of illness. With customary treatment patterns, the costs of migraine associated with reduced functional capacity are substantial. The migraine model represents a flexible tool for the economic evaluation of different migraine treatments in various populations.

  20. Light's labour's lost - policies for energy-efficient lighting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-29

    When William Shakepeare wrote Love's Labour's Lost he would have used light from tallow candles at a cost (today) of 12,000 British pounds per million-lumen hours. The same amount of light from electric lamps now costs only 2 pounds! But today's low-cost illumination still has a dark side. Globally, lighting consumes more electricity than is produced by either hydro or nuclear power and results in CO2 emissions equivalent to two thirds of the world's cars. A standard incandescent lamp may be much more efficient than a tallow candle, but it is far less efficient than a high-pressure sodium lamp. Were inefficient light sources to be replaced by the equivalent efficient ones, global lighting energy demand would be up to 40% less at a lower overall cost. Larger savings still could be realised through the intelligent use of controls, lighting levels and daylight. But achieving efficient lighting is not just a question of technology; it requires policies to transform current practice. This book documents the broad range of policy measures to stimulate efficient lighting that have already been implemented around the world and suggests new ways these could be strengthened to prevent light's labour's from being lost.

  1. A novel tissue engineering technique for regeneration of lost interdental papillary height

    Directory of Open Access Journals (Sweden)

    Rutuj Surana

    2010-01-01

    Full Text Available Open interdental spaces caused by papillary gingival recession are one of the most common problems faced in dentistry. Surgical and nonsurgical periodontal treatments for regeneration of lost papillary height have been reported with limited success. The present study reports effectiveness of autologous cultured fibroblast injections, a tissue engineering technique for papillary regeneration. A black triangle caused by Tarnow′s and Nordland′s class I papillary gingival loss was reported in maxillary anterior region of a young male patient. An autologous gingival biopsy was cultured in a biotechnology lab for the growth and expansion of fibroblasts. Cultured fibroblast suspension was injected into the receded papilla twice at an interval of 5 days. Follow-ups were recorded on the 6th day, 15 th day, at 1 month and at 2 months. Complete fill of black triangle was noted at the end of 2 months. No inflammatory or immune reactions were noted at the site of injection. Autologous cultured fibroblast injections are safe, efficacious, and an acceptable treatment option for the regeneration of lost papillary height.

  2. Development and implementation of a nurse-led walk-in centre: evidence lost in translation?

    Science.gov (United States)

    Desborough, Jane; Parker, Rhian; Forrest, Laura

    2013-07-01

    The design of the first Australian public nurse-led primary care walk-in centre was modelled on those established in the English National Health Service (NHS). An independent evaluation of the first 12 months of operation of the Australian Capital Territory (ACT) Health walk-in centre, in 2011, analysed the translation of evidence from the national evaluation of the NHS walk-in centres to the policy development and implementation of the ACT walk-in centre. Whilst in a number of ways the evidence was used well, our interest for this paper was to examine three areas identified as problematic and to identify the points at which the evidence was lost or diluted. In addition to data obtained through nurse and key stakeholder interviews for the evaluation, an analysis was undertaken of documents on the planning and establishment of the ACT walk-in centre, either provided to the evaluation team or made publicly available. Three areas were identified as problematic in the way that evidence from the NHS evaluation was translated: the use of clinical decision support software (CDSS); the marketing of the walk-in centre; and its location. Our examination indicates that despite seeking evidence to inform the development of the ACT walk-in centre, the evidence was not fully used and some clear lessons ignored, resulting in much of the evidence being lost in translation.

  3. 'Lost to follow up': rethinking delayed and interrupted HIV treatment among married Swazi women.

    Science.gov (United States)

    Dlamini-Simelane, Thandeka T T; Moyer, Eileen

    2017-03-01

    Through various campaigns and strategies, more women are being tested for HIV in countries with a high prevalence of the virus. Despite the ready availability of treatment at government clinics in sub-Saharan African countries like Swaziland, women consistently report difficulty in maintaining access to treatment. Drawing on two individual case studies selected from a larger study of the so-called leaky cascade in Swaziland, we illustrate the protracted journeys married women undertake to initiate treatment. We demonstrate how women manoeuvre tactically after diagnosis, highlight factors that influence their decisions related to initiating treatment, and detail the actors involved in the decision-making process. Our research shows the persistence of structural factors that inhibit access, including economic constraints, gender inequality and patriarchal social norms. Patients referred as ‘lost to follow up’ are in many cases actively pursuing treatment within a context that includes the biomedical health system, but also extends well beyond it. We argue that the phrase ‘lost to follow up’ conceals the complex social navigation required by women to initiate and maintain access to treatment. Further, we suggest that many of the logistical challenges of monitoring and tracking people with HIV can be better addressed by taking into account the structural and social aspects of delayed treatment initiative.

  4. Characteristics of Children Who Lost the Diagnosis of Autism: A Sample from Istanbul, Turkey

    Directory of Open Access Journals (Sweden)

    Nahit Motavalli Mukaddes

    2014-01-01

    Full Text Available Aim. The aim of this study was to describe a group of children who lost a diagnosis of autism following participation in early educational programs. Method. This is a descriptive study reporting the characteristics of children (n: 39 who lost their diagnosis of autism and explaining the educational programs that these children followed. The data were collected by reviewing the participants’ files and through examinations. Results. All of the children were placed at regular psychiatric follow-ups. The mean age at referral was 2.39±0.75 years, whereas the mean age at the time of optimal outcome reported was 5.11±1.95 years. Two of the children were in early intensive behavioral intervention (EIBI, and the rest were in a comprehensive naturalistic behavioral program. The childhood autism rating scale (CARS total scores at baseline and final were 32.75±3.15 and 18.01±1.76, respectively. The mean IQ of the group at final examination was 116.70±18.88. Conclusion. It could be concluded that a group of children with an autism diagnosis could lose the diagnosis of autism upon early intervention. High IQ and the development of communicative and language skills at an early age could be the most powerful factors contributing to an optimal outcome.

  5. First satellite tracks of neonate sea turtles redefine the ‘lost years’ oceanic niche

    Science.gov (United States)

    Mansfield, Katherine L.; Wyneken, Jeanette; Porter, Warren P.; Luo, Jiangang

    2014-01-01

    Few at-sea behavioural data exist for oceanic-stage neonate sea turtles, a life-stage commonly referred to as the sea turtle ‘lost years’. Historically, the long-term tracking of small, fast-growing organisms in the open ocean was logistically or technologically impossible. Here, we provide the first long-term satellite tracks of neonate sea turtles. Loggerheads (Caretta caretta) were remotely tracked in the Atlantic Ocean using small solar-powered satellite transmitters. We show that oceanic-stage turtles (i) rarely travel in Continental Shelf waters, (ii) frequently depart the currents associated with the North Atlantic Subtropical Gyre, (iii) travel quickly when in Gyre currents, and (iv) select sea surface habitats that are likely to provide a thermal benefit or refuge to young sea turtles, supporting growth, foraging and survival. Our satellite tracks help define Atlantic loggerhead nursery grounds and early loggerhead habitat use, allowing us to re-examine sea turtle ‘lost years’ paradigms. PMID:24598420

  6. Has Human Evolution Stopped?

    Directory of Open Access Journals (Sweden)

    Alan R. Templeton

    2010-07-01

    Full Text Available It has been argued that human evolution has stopped because humans now adapt to their environment via cultural evolution and not biological evolution. However, all organisms adapt to their environment, and humans are no exception. Culture defines much of the human environment, so cultural evolution has actually led to adaptive evolution in humans. Examples are given to illustrate the rapid pace of adaptive evolution in response to cultural innovations. These adaptive responses have important implications for infectious diseases, Mendelian genetic diseases, and systemic diseases in current human populations. Moreover, evolution proceeds by mechanisms other than natural selection. The recent growth in human population size has greatly increased the reservoir of mutational variants in the human gene pool, thereby enhancing the potential for human evolution. The increase in human population size coupled with our increased capacity to move across the globe has induced a rapid and ongoing evolutionary shift in how genetic variation is distributed within and among local human populations. In particular, genetic differences between human populations are rapidly diminishing and individual heterozygosity is increasing, with beneficial health effects. Finally, even when cultural evolution eliminates selection on a trait, the trait can still evolve due to natural selection on other traits. Our traits are not isolated, independent units, but rather are integrated into a functional whole, so selection on one trait can cause evolution to occur on another trait, sometimes with mildly maladaptive consequences.

  7. Time Trend of the People lost follow up on Antiretroviral Therapy (ART Services in Nepal: A Epidemiological Modelling

    Directory of Open Access Journals (Sweden)

    Brijesh Sathian

    2014-06-01

    Full Text Available Background: The real state about the spread of the HIV epidemic in Nepal is not clear since the details available are on the basis of repeated integrated biological and behavioral surveillance. Objective To study the trends of People lost follow up on ART in future. Material and methods: A retrospective study was carried out on the data collected from the Health ministry records of Nepal, between 2006 and 2012. Descriptive statistics and statistical modelling were used for the analysis and forecasting of data. Results: Including the constant term from the equation, the quadratic model was the best fit, for the forecasting of People lost follow up on ART. Using quadratic equation, it is estimated that 4331 reported number of People lost follow up on ART will be there in Nepal by the year 2020. Conclusion: The People lost follow up on ART in Nepal are having an increasing trend. Estimates of the total number of People lost follow up on ART attributable to the major routes of infection make an important contribution to public health policy. They can be used for the planning of healthcare services and for contributing to estimates of the future numbers with People lost follow up on ART used for planning health promotion programmes.

  8. Obesity as a Possible Risk Factor for Lost-time Injury in Registered Nurses: A Literature Review

    Directory of Open Access Journals (Sweden)

    Gillian Jordan

    2015-03-01

    Full Text Available Time-loss injuries are still a major occurrence in Canada, injuring thousands of Canadian workers each year. With obesity rates on the rise across the country, as well as around the world, it is important that the possible effects of obesity in the workplace be fully understood, especially those effects linked to lost-time injuries. The aim of this paper was to evaluate predictors of workplace lost-time injuries and how they may be related to obesity or high body mass index by examining factors associated with lost-time injuries in the health care sector, a well-studied industry with the highest number of reported time loss injuries in Canada. A literature review focusing on lost-time injuries in Registered Nurses (RNs was conducted using the keywords and terms: lost time injury, workers' compensation, occupational injury, workplace injury, injury, injuries, work, workplace, occupational, nurse, registered nurse, RN, health care, predictors, risk factors, risk, risks, cause, causes, obese, obesity, and body mass index. Data on predictors or factors associated with lost-time injuries in RNs were gathered and organized using Loisel's Work Disability Prevention Management Model and extrapolated upon using existing literature surrounding obesity in the Canadian workplace.

  9. Evolution of the metazoan mitochondrial replicase.

    Science.gov (United States)

    Oliveira, Marcos T; Haukka, Jani; Kaguni, Laurie S

    2015-03-03

    The large number of complete mitochondrial DNA (mtDNA) sequences available for metazoan species makes it a good system for studying genome diversity, although little is known about the mechanisms that promote and/or are correlated with the evolution of this organellar genome. By investigating the molecular evolutionary history of the catalytic and accessory subunits of the mtDNA polymerase, pol γ, we sought to develop mechanistic insight into its function that might impact genome structure by exploring the relationships between DNA replication and animal mitochondrial genome diversity. We identified three evolutionary patterns among metazoan pol γs. First, a trend toward stabilization of both sequence and structure occurred in vertebrates, with both subunits evolving distinctly from those of other animal groups, and acquiring at least four novel structural elements, the most important of which is the HLH-3β (helix-loop-helix, 3 β-sheets) domain that allows the accessory subunit to homodimerize. Second, both subunits of arthropods and tunicates have become shorter and evolved approximately twice as rapidly as their vertebrate homologs. And third, nematodes have lost the gene for the accessory subunit, which was accompanied by the loss of its interacting domain in the catalytic subunit of pol γ, and they show the highest rate of molecular evolution among all animal taxa. These findings correlate well with the mtDNA genomic features of each group described above, and with their modes of DNA replication, although a substantive amount of biochemical work is needed to draw conclusive links regarding the latter. Describing the parallels between evolution of pol γ and metazoan mtDNA architecture may also help in understanding the processes that lead to mitochondrial dysfunction and to human disease-related phenotypes. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  10. 27 CFR 19.32 - Assessment of tax on spirits, denatured spirits, or wines in bond which are lost, destroyed or...

    Science.gov (United States)

    2010-04-01

    ... spirits, denatured spirits, or wines in bond which are lost, destroyed or removed without authorization... spirits, denatured spirits, or wines in bond which are lost, destroyed or removed without authorization. When spirits, denatured spirits, or wines in bond are lost or destroyed (except spirits, denatured...

  11. Multicolour Observations, Inhomogeneity & Evolution

    OpenAIRE

    Hellaby, Charles

    2000-01-01

    We propose a method of testing source evolution theories that is independent of the effects of inhomogeneity, and thus complementary to other studies of evolution. It is suitable for large scale sky surveys, and the new generation of large telescopes. In an earlier paper it was shown that basic cosmological observations - luminosity versus redshift, area distance versus redshift and number counts versus redshift - cannot separate the effects of cosmic inhomogeneity, cosmic evolution and sourc...

  12. Oxygen evolution reaction catalysis

    Energy Technology Data Exchange (ETDEWEB)

    Haber, Joel A.; Jin, Jian; Xiang, Chengxiang; Gregoire, John M.; Jones, Ryan J.; Guevarra, Dan W.; Shinde, Aniketa A.

    2016-09-06

    An Oxygen Evolution Reaction (OER) catalyst includes a metal oxide that includes oxygen, cerium, and one or more second metals. In some instances, the cerium is 10 to 80 molar % of the metals in the metal oxide and/or the catalyst includes two or more second metals. The OER catalyst can be included in or on an electrode. The electrode can be arranged in an oxygen evolution system such that the Oxygen Evolution Reaction occurs at the electrode.

  13. Stellar structure and evolution

    International Nuclear Information System (INIS)

    Kippernhahn, R.; Weigert, A.

    1990-01-01

    This book introduces the theory of the internal structure of stars and their evolution in time. It presents the basic physics of stellar interiors, methods for solving the underlying equations, and the most important results necessary for understanding the wide variety of stellar types and phenomena. The evolution of stars is discussed from their birth through normal evolution to possibly spectacular final stages. Chapters on stellar oscillations and rotation are included

  14. Days lost due to disability of diclofenac-induced adverse drug reactions

    Directory of Open Access Journals (Sweden)

    Thomas D

    2012-03-01

    Full Text Available Disability Adjusted Life Years (DALY is a widely used measure to quantify the burden of diseases or illness. DALYs for a disease is calculated as the sum of the Years of Life Lost (YLL due to premature mortality in the population and the equivalent healthy Years Lost due to Disability (YLD. The only difference from the YLD and Days Lost due to Disability (DLD calculation is that instead of considering the duration of Adverse Drug Reaction (ADR in years, it is calculated in days. Objective: DLD was measured for diclofenac tablets to prepare the ADR profile.Methods: The study was done on the patients (18-65 years old attending the community pharmacy at Kasaragod district, South India, with prescription of diclofenac tablets. Patients reported ADRs on their next visit to the pharmacy or they had called to the provided phone number and reported it. Disability Weight (DW was calculated in an analogue scale from 0-1. Zero represent complete health and 1 represent death or equivalent condition. DW was multiplied with occurrence and duration of ADRs in days.Results: About 943 patients received diclofenac tablets in 1000 prescriptions were successfully followed up for possible, probable and definite ADRs. A total of 561 reactions reported in 2010 for diclofenac tablet in the study population. There were 34 different types of ADRs under 12 physiological systems/organs. Most common reactions were on gastrointestinal (GI system (48%, followed by skin (14%, Central Nervous System (10%, renal (7%, and cardiovascular (7%. Abdominal pain, cramps or flatulence was the highest occurring GI ADR (107, followed by 43 rashes, 42 nausea/vomiting, 37 indigestion, 34 peptic ulcers, 31 edema etc. DLD for peptic ulcer was considerably high (0.078 per 1000 of the study population on diclofenac. The most damaging ADR were peptic ulcer with or without perforation, followed by rash 0.036 DLD and edema 0.027 DLD. There was considerable DLD by acute renal failure (0.012 Steven

  15. Calculating expected years of life lost for assessing local ethnic disparities in causes of premature death

    Directory of Open Access Journals (Sweden)

    Katcher Brian S

    2008-04-01

    Full Text Available Abstract Background A core function of local health departments is to conduct health assessments. The analysis of death certificates provides information on diseases, conditions, and injuries that are likely to cause death – an important outcome indicator of population health. The expected years of life lost (YLL measure is a valid, stand-alone measure for identifying and ranking the underlying causes of premature death. The purpose of this study was to rank the leading causes of premature death among San Francisco residents, and to share detailed methods so that these analyses can be used in other local health jurisdictions. Methods Using death registry data and population estimates for San Francisco deaths in 2003–2004, we calculated the number of deaths, YLL, and age-standardized YLL rates (ASYRs. The results were stratified by sex, ethnicity, and underlying cause of death. The YLL values were used to rank the leading causes of premature death for men and women, and by ethnicity. Results In the years 2003–2004, 6312 men died (73,627 years of life lost, and 5726 women died (51,194 years of life lost. The ASYR for men was 65% higher compared to the ASYR for women (8971.1 vs. 5438.6 per 100,000 persons per year. The leading causes of premature deaths are those with the largest average YLLs and are largely preventable. Among men, these were HIV/AIDS, suicide, drug overdose, homicide, and alcohol use disorder; and among women, these were lung cancer, breast cancer, hypertensive heart disease, colon cancer, and diabetes mellitus. A large health disparity exists between African Americans and other ethnic groups: African American age-adjusted overall and cause-specific YLL rates were higher, especially for homicide among men. Except for homicide among Latino men, Latinos and Asians have comparable or lower YLL rates among the leading causes of death compared to whites. Conclusion Local death registry data can be used to measure, rank, and

  16. The influence of the parameters of lost foam process on the quality of aluminum alloys castings

    Directory of Open Access Journals (Sweden)

    Aćimović-Pavlović Zagorka

    2010-01-01

    Full Text Available This paper presents the research results of application of Lost foam process for aluminum alloys castings of a simple geometry. The process characteristic is that patterns and gating of moulds, made of polymers, stay in the mould till the liquid metal inflow. In contact with the liquid metal, pattern intensely and in relatively short time decomposes and evaporates, which is accompanied by casting crystallization. As a consequence of polymer pattern decomposition and evaporation a great quantity of liquid and gaseous products are produced, which is often the cause of different types of casting errors. This paper presents the results of a research with a special consideration given to detecting and analyzing the errors of castings. In most cases the cause of these errors are defects of polymer materials used for evaporable patterns production, as well as defects of materials for refractory coatings production for polymer patterns. The researches have shown that different types of coatings determine properties of the obtained castings. Also, the critical processing parameters (polymer pattern density, casting temperature, permeability of refractory coating and sand, construction of patterns and gating of moulds significantly affect on castings quality. During the research a special consideration was given to control and optimization of these parameters with the goal of achieving applicable castings properties. The study of surface and internal error of castings was performed systematically in order to carry out preventive measures to avoid errors and minimize production costs. In order to achieve qualitative and profitable castings production by the method of Lost foam it is necessary to reach the balance in the system: evaporable polymer pattern - liquid metal - refractory coating - sandy cast in the phase of metal inflow, decomposition and evaporation of polymer pattern, formation and solidification of castings. By optimizing the processing

  17. Adaptability and evolution.

    Science.gov (United States)

    Bateson, Patrick

    2017-10-06

    The capacity of organisms to respond in their own lifetimes to new challenges in their environments probably appeared early in biological evolution. At present few studies have shown how such adaptability could influence the inherited characteristics of an organism's descendants. In part, this has been because organisms have been treated as passive in evolution. Nevertheless, their effects on biological evolution are likely to have been important and, when they occurred, accelerated the pace of evolution. Ways in which this might have happened have been suggested many times since the 1870s. I review these proposals and discuss their relevance to modern thought.

  18. Lost sleep and cyberloafing: Evidence from the laboratory and a daylight saving time quasi-experiment.

    Science.gov (United States)

    Wagner, David T; Barnes, Christopher M; Lim, Vivien K G; Ferris, D Lance

    2012-09-01

    The Internet is a powerful tool that has changed the way people work. However, the ubiquity of the Internet has led to a new workplace threat to productivity-cyberloafing. Building on the ego depletion model of self-regulation, we examine how lost and low-quality sleep influence employee cyberloafing behaviors and how individual differences in conscientiousness moderate these effects. We also demonstrate that the shift to Daylight Saving Time (DST) results in a dramatic increase in cyberloafing behavior at the national level. We first tested the DST-cyberloafing relation through a national quasi-experiment, then directly tested the relation between sleep and cyberloafing in a closely controlled laboratory setting. We discuss the implications of our findings for theory, practice, and future research.

  19. Modelling small-area inequality in premature mortality using years of life lost rates

    Science.gov (United States)

    Congdon, Peter

    2013-04-01

    Analysis of premature mortality variations via standardized expected years of life lost (SEYLL) measures raises questions about suitable modelling for mortality data, especially when developing SEYLL profiles for areas with small populations. Existing fixed effects estimation methods take no account of correlations in mortality levels over ages, causes, socio-ethnic groups or areas. They also do not specify an underlying data generating process, or a likelihood model that can include trends or correlations, and are likely to produce unstable estimates for small-areas. An alternative strategy involves a fully specified data generation process, and a random effects model which "borrows strength" to produce stable SEYLL estimates, allowing for correlations between ages, areas and socio-ethnic groups. The resulting modelling strategy is applied to gender-specific differences in SEYLL rates in small-areas in NE London, and to cause-specific mortality for leading causes of premature mortality in these areas.

  20. Lost or fond? Effects of nostalgia on sad mood recovery vary by attachment insecurity.

    Science.gov (United States)

    Cavanagh, Sarah R; Glode, Ryan J; Opitz, Philipp C

    2015-01-01

    Nostalgia involves a fond recollection of people and events lost to time. Growing evidence indicates that nostalgia may ameliorate negative affective states such as loneliness and boredom. However, the effect of nostalgia on sadness is unknown, and there is little research on how social connectedness might impact nostalgia's effects. Grounded in a theoretical framework whereby people with lower levels of attachment insecurity benefit more from nostalgia, we exposed participants to a mortality-related sad mood and then randomly assigned them to reflect on a nostalgic or an ordinary event memory. We examined changes in mood and electrodermal activity (EDA) and found that nostalgic versus ordinary event memories led to a blunted recovery from sad mood, but that this effect was moderated by degree of attachment insecurity, such that participants with low insecurity benefited from nostalgia whereas people with high insecurity did not. These findings suggest that nostalgia's benefits may be tied to the degree of confidence one has in one's social relationships.

  1. The lost steps of infancy: symbolization, analytic process and the growth of the self.

    Science.gov (United States)

    Feldman, Brian

    2002-07-01

    In 'The Lost Steps' the Latin American novelist Alejo Carpentier describes the search by the protagonist for the origins of music among native peoples in the Amazon jungle. This metaphor can be utilized as a way of understanding the search for the pre-verbal origins of the self in analysis. The infant's experience of the tempo and rhythmicity of the mother/infant interaction and the bathing in words and sounds of the infant by the mother are at the core of the infant's development of the self. The infant observation method (Tavistock model) will be looked at as a way of developing empathy in the analyst to better understand infantile, pre-verbal states of mind. A case vignette from an adult analysis will be utilized to illustrate the theoretical concepts.

  2. Influence of the cordierite lining on the lost foam casting process

    Directory of Open Access Journals (Sweden)

    Trumbulović Ljiljana

    2003-01-01

    Full Text Available This paper discuss the influence of the refractory cordierite lining on the structure and mechanical properties of Al-Si and Al-Cu casings obtained from the Lost foam casting process. So far there has not been any report of the research on cordierite lining in the literature and moreover the cordierite ceramics have never been used in foundries. In the light of these facts this paper investigates the possibility of using cordierite for manufacturing evaporable model refractory linings. Our results indicate that the application of cordierite ceramics is comparable to talc-based refractory linings in both Al-Cu and Al-Si castings, while cordierites are favorable in Al-Cu case due to their higher melting temperature.

  3. Lost salt technique for severely resorbed alveolar ridges: An innovative approach

    Directory of Open Access Journals (Sweden)

    Himanshi Aggarwal

    2012-01-01

    Full Text Available The success of a complete denture relies on the principles of retention, stability and support. The prosthodontist skill lies in applying these principles efficiently in critical situations. Severely resorbed maxillary edentulous ridges that are narrow and constricted with increased inter ridge space provide decreased support, retention and stability. The consequent weight of the processed denture only compromises them further. This article describes a case report of an edentulous patient with resorbed ridges where a simplified technique of fabricating a hollow maxillary complete denture using lost salt technique was used for preservation of denture bearing areas. The hollowing of the denture reduces the weight of the denture, thereby enhancing stability and retention, reducing the further resorption of the jaws.

  4. Recent eolian activity and paleoclimate fluctuations in the Ferris Lost Soldier Area, South-Central Wyoming

    Science.gov (United States)

    Gaylord, D. R.

    1983-09-01

    The Ferris Dune Fields were examined. Sand dunes are especially valuable in paleoclimate reconstructions because they: (1) bury and preserve datable materials and artifacts; (2) respond to even subtle changes in wind velocity and direction as reflected both in external morphology and internal structures; and (3) remain unconsolidated, making them amenable to easy textural and compositional examination. The valley of Clear Creek in the Ferris Dunes reveals a relatively continuous Holocene section of interbedded dune and interdunal pond deposits. Radiocarbon dates from the interdunal pond strata at Clear Creek, theoretical sand dune migration rates, compositional analysis of periglacial sand wedges, and relative dating of actively migrating parabolic dunes reveals a general sequence of geologic-climatic events that affected the Ferris-Lost Soldier area. The most recent major reactivaton of dunes occurred approximately 290 years ago.

  5. Psychiatric Symptoms and Barriers to Care in HIV-Infected Individuals Who Are Lost to Care.

    Science.gov (United States)

    McLean, Carmen P; Gay, Natalie G; Metzger, David A; Foa, Edna B

    Past studies of barriers to HIV care have not comprehensively assessed psychiatric symptoms, and few have assessed barriers to care among people living with HIV (PLWH) who are lost to care (LTC). We examined psychiatric symptoms, barriers to HIV care, and immune functioning in PLWH who were retained in care (RIC; n = 21) or LTC (n = 21). Participants completed diagnostic interviews for posttraumatic stress disorder (PTSD) and other psychiatric disorders, self-report measures of HIV risk behaviors and psychiatric symptoms, and a blood draw to assess viral load. Compared to RIC participants, LTC participants met criteria for a greater number of psychiatric disorders and reported greater depressive symptoms and more barriers to HIV care. There were no group differences in PTSD severity, risk behaviors, or viral load, suggesting that LTC individuals experience greater psychiatric problems and perceive more barriers to care than RIC participants, but are not less likely to have achieved viral suppression.

  6. Mexican business structure between 2003 and 2008: towards the fourth lost decade

    Directory of Open Access Journals (Sweden)

    Gaspar Núñez R.

    2013-01-01

    Full Text Available This research examines Mexican firm structure and performance during the years 2003 and 2008, using data from the 2004 and 2009 Economic Census. We find that the poor firm structure of year 2003 is even worst in 2008. Detailed analysis of variables relevant for economic performance and future development, confirms that the period 2001-2010 was indeed a third lost decade, and that the current firm structure makes it impossible to achieve a meaningful economic development for the 2011-2020 decade. Results also confirm one of the main thesis in current literature, namely, that lack of investment in physical capital is one of the main causes of economy stagnation.

  7. Water resources in the Big Lost River Basin, south-central Idaho

    Science.gov (United States)

    Crosthwaite, E.G.; Thomas, C.A.; Dyer, K.L.

    1970-01-01

    The Big Lost River basin occupies about 1,400 square miles in south-central Idaho and drains to the Snake River Plain. The economy in the area is based on irrigation agriculture and stockraising. The basin is underlain by a diverse-assemblage of rocks which range, in age from Precambrian to Holocene. The assemblage is divided into five groups on the basis of their hydrologic characteristics. Carbonate rocks, noncarbonate rocks, cemented alluvial deposits, unconsolidated alluvial deposits, and basalt. The principal aquifer is unconsolidated alluvial fill that is several thousand feet thick in the main valley. The carbonate rocks are the major bedrock aquifer. They absorb a significant amount of precipitation and, in places, are very permeable as evidenced by large springs discharging from or near exposures of carbonate rocks. Only the alluvium, carbonate rock and locally the basalt yield significant amounts of water. A total of about 67,000 acres is irrigated with water diverted from the Big Lost River. The annual flow of the river is highly variable and water-supply deficiencies are common. About 1 out of every 2 years is considered a drought year. In the period 1955-68, about 175 irrigation wells were drilled to provide a supplemental water supply to land irrigated from the canal system and to irrigate an additional 8,500 acres of new land. Average. annual precipitation ranged from 8 inches on the valley floor to about 50 inches at some higher elevations during the base period 1944-68. The estimated water yield of the Big Lost River basin averaged 650 cfs (cubic feet per second) for the base period. Of this amount, 150 cfs was transpired by crops, 75 cfs left the basin as streamflow, and 425 cfs left as ground-water flow. A map of precipitation and estimated values of evapotranspiration were used to construct a water-yield map. A distinctive feature of the Big Lost River basin, is the large interchange of water from surface streams into the ground and from the

  8. Paradise lost: a case of hysteria illustrating a specific dynamic of seduction trauma.

    Science.gov (United States)

    Adams-Silvan, A; Silvan, M

    1994-06-01

    This paper presents extensive clinical data illustrating the case of a middle-aged woman, who as a child participated in an extended sexual relationship with her elder brother. The patient suffered from an hysterical personality disorder with somatic distress and a compulsion to repeat disastrous social and work situations. In her treatment, the patient re-enacted the seduction and subsequent experience in various ways. The analysis and understanding of her symptoms, social problems and re-enactments in the transference strongly suggested that the trauma of her seduction was the result of the loss of precociously stimulated and experienced pleasure rather than loss of impulse control. The compulsion to repeat apparently represented the wish not only to master, but the desire to return to the pleasure of the experience as a true compromise formation. Although many other dynamics were of course operative, interpretations of her wish to recreate the lost pleasures were most helpful.

  9. Impacts of lost fast ions on the TJ-II Vacuum Vessel during NBI

    International Nuclear Information System (INIS)

    Guasp, J.

    1995-01-01

    The possible deposition patterns, on the Vacuum Vessel, of lost fast ions during the balanced tangential NBI in TJ-II helical axis Stellarator are analysed theoretically, establishing the relation between those impact points, the plasma exit and birth positions and the magnetic configuration characteristics. It is shown that direct losses are the most important, mainly those produced by the beam injected with the same direction that the magnetic field, increasing with beam energy and plasma density but with impacts remaining fixed on well defined zones, a periodically distributed along the Hard Core cover plates, producing high loads at high densities. The remaining losses, except for the shine through ones that predominate at low density, are periodically distributed, with smooth maxima and produce very low loads. No overlapping between the different kind of losses or beams is observed. (Author) 6 refs

  10. Characterization of waste ceramic process for lost wax casting for employment as pozzolan

    International Nuclear Information System (INIS)

    Machado, C.F.; Moravia, W.G.

    2012-01-01

    There are about 30 companies of Lost Wax Casting in Brazil, and each one of them disposes around 50 to 100 tons of waste ceramic shell monthly. This work is concerned in the physical, chemical and microstructural characterization to evaluated the reactivity of this material. It was analyzed also the environmental risk of the material. The tests were made with a ceramic shell ground to evaluate the aspect of sustainable waste. In the physical characterization of the waste the density, specific surface area and distribution of the particle size were analyzed. In the chemical characterization, the powder was subjected to essays of fluorescence and pozzolanic activity. As for microstructural characterization scanning electron microscopy and Xray diffraction were carried out. The analysis of results shows that the ceramic shell powder is classified as non-inert waste, II-A Class, with density of 2,59 g/cm³. (author)

  11. A novel lost packets recovery scheme based on visual secret sharing

    Science.gov (United States)

    Lu, Kun; Shan, Hong; Li, Zhi; Niu, Zhao

    2017-08-01

    In this paper, a novel lost packets recovery scheme which encrypts the effective parts of an original packet into two shadow packets based on (2, 2)-threshold XOR-based visual Secret Sharing (VSS) is proposed. The two shadow packets used as watermarks would be embedded into two normal data packets with digital watermarking embedding technology and then sent from one sensor node to another. Each shadow packet would reveal no information of the original packet, which can improve the security of original packet delivery greatly. The two shadow packets which can be extracted from the received two normal data packets delivered from a sensor node can recover the original packet lossless based on XOR-based VSS. The Performance analysis present that the proposed scheme provides essential services as long as possible in the presence of selective forwarding attack. The proposed scheme would not increase the amount of additional traffic, namely, lower energy consumption, which is suitable for Wireless Sensor Network (WSN).

  12. Impacts of lost fast ions on the TJ-II Vacuum vessel during NBI

    International Nuclear Information System (INIS)

    Guasp, J.

    1995-09-01

    The possible deposition patterns, on the Vacuum Vessel, of lost fast ions during the balanced tangential NBI in TJ-II helical axis Stellarator are analysed theoretically, establishing the relation between those impact points, the plasma exit and birth positions and positions and the magnetic configuration characteristics. It is shown that direct losses are the most important, mainly those produced by the beam injected with the same direction that the magnetic field, increasing with beam energy and plasma density but with impacts remaining fixed on well defined zones, a periodically distributed along the Hard Core cover plates, producing high loads at high densities. The remaining losses, except for the shine through ones that predominate at low density, are periodically distributed, with smooth maxima and produce very low loads. No overlapping between the different kind of losses or beams is observed

  13. Fill rate estimation in periodic review policies with lost sales using simple methods

    Energy Technology Data Exchange (ETDEWEB)

    Cardós, M.; Guijarro Tarradellas, E.; Babiloni Griñón, E.

    2016-07-01

    Purpose: The exact estimation of the fill rate in the lost sales case is complex and time consuming. However, simple and suitable methods are needed for its estimation so that inventory managers could use them. Design/methodology/approach: Instead of trying to compute the fill rate in one step, this paper focuses first on estimating the probabilities of different on-hand stock levels so that the fill rate is computed later. Findings: As a result, the performance of a novel proposed method overcomes the other methods and is relatively simple to compute. Originality/value: Existing methods for estimating stock levels are examined, new procedures are proposed and their performance is assessed.

  14. De onde somos e para onde vamos? Um olhar pós-moderno em Lost

    Directory of Open Access Journals (Sweden)

    Lucas Gomes-Thimóteo

    2012-01-01

    Full Text Available Este artículo analiza la serie televisiva Lost desde dos miradas. La primera caracteriza su estructura como una narrativa transmedia, un formato resultante de la cultura de la convergencia, la que emerge en nuestro tiempo con la masificación de contenidos y medios de comunicación que nos circundan. Ello hace que los diversos textos existentes necesiten de la actuación del televidente para tejerlos y, así, crear nuevos significados. Además, algunos elementos presentes en la serie se muestran correlacionados a temas abordados por la postmodernidad; de esa forma, se propone demostrar cómo la narrativa presentada reproduce situaciones de la realidad en su ficción, lo que proporciona una identificación del sujeto postmoderno con la serie.

  15. Sources of organic nitrogen at the serpentinite-hosted Lost City hydrothermal field.

    Science.gov (United States)

    Lang, S Q; Früh-Green, G L; Bernasconi, S M; Butterfield, D A

    2013-03-01

    The reaction of ultramafic rocks with water during serpentinization at moderate temperatures results in alkaline fluids with high concentrations of reduced chemical compounds such as hydrogen and methane. Such environments provide unique habitats for microbial communities capable of utilizing these reduced compounds in present-day and, possibly, early Earth environments. However, these systems present challenges to microbial communities as well, particularly due to high fluid pH and possibly the availability of essential nutrients such as nitrogen. Here we investigate the source and cycling of organic nitrogen at an oceanic serpentinizing environment, the Lost City hydrothermal field (30°N, Mid-Atlantic Ridge). Total hydrolizable amino acid (THAA) concentrations in the fluids range from 736 to 2300 nm and constitute a large fraction of the dissolved organic carbon (2.5-15.1%). The amino acid distributions, and the relative concentrations of these compounds across the hydrothermal field, indicate they most likely derived from chemolithoautotrophic production. Previous studies have identified the presence of numerous nitrogen fixation genes in the fluids and the chimneys. Organic nitrogen in actively venting chimneys has δ(15) N values as low as 0.1‰ which is compatible with biological nitrogen fixation. Total hydrolizable amino acids in the chimneys are enriched in (13) C by 2-7‰ compared to bulk organic matter. The distribution and absolute δ(13) C(THAA) values are compatible with a chemolithoautotrophic source, an attribution also supported by molar organic C/N ratios in most active chimneys (4.1-5.5) which are similar to those expected for microbial communities. In total, these data indicate nitrogen is readily available to microbial communities at Lost City. © 2013 Blackwell Publishing Ltd.

  16. Potential years lost and life expectancy in adults with newly diagnosed epilepsy.

    Science.gov (United States)

    Granbichler, Claudia A; Zimmermann, Georg; Oberaigner, Willi; Kuchukhidze, Giorgi; Ndayisaba, Jean-Pierre; Taylor, Alexandra; Luef, Gerhard; Bathke, Arne C; Trinka, Eugen

    2017-11-01

    Studies using relative measures, such as standardized mortality ratios, have shown that patients with epilepsy have an increased mortality. Reports on more direct and absolute measure such as life expectancy are sparse. We report potential years lost and how life expectancy has changed over 40 years in a cohort of patients with newly diagnosed epilepsy. We analyzed life expectancy in a cohort of adult patients diagnosed with definite epilepsy between 1970 and 2010. Those with brain tumor as cause of epilepsy were excluded. By retrospective probabilistic record linkage, living or death status was derived from the national death registry. We estimated life expectancy by a Weibull regression model using gender, age at diagnosis, epilepsy etiology, and year of diagnosis as covariates at time of epilepsy diagnosis, and 5, 10, 15, and 20 years after diagnosis. Results were compared to the general population, and 95% confidence intervals are given. There were 249 deaths (105 women, age at death 19.0-104.0 years) in 1,112 patients (11,978.4 person-years, 474 women, 638 men). A substantial decrease in life expectancy was observed for only a few subgroups, strongly depending on epilepsy etiology and time of diagnosis: time of life lost was highest in patients with symptomatic epilepsy diagnosed between 1970 and 1980; the impact declined with increasing time from diagnosis. Over half of the analyzed subgroups did not differ significantly from the general population. This effect was reversed in the later decades, and life expectancy was prolonged in some subgroups, reaching a maximum in those with newly diagnosed idiopathic and cryptogenic epilepsy between 2001 and 2010. Life expectancy is reduced in symptomatic epilepsies. However, in other subgroups, a prolonged life expectancy was found, which has not been reported previously. Reasons may be manifold and call for further study. © 2017 The Authors. Epilepsia published by Wiley Periodicals, Inc. on behalf of International

  17. An estimated cost of lost climate regulation services caused by thawing of the Arctic cryosphere.

    Science.gov (United States)

    Euskirchen, Eugénie S; Goodstein, Eban S; Huntington, Henry P

    2013-12-01

    Recent and expected changes in Arctic sea ice cover, snow cover, and methane emissions from permafrost thaw are likely to result in large positive feedbacks to climate warming. There is little recognition of the significant loss in economic value that the disappearance of Arctic sea ice, snow, and permafrost will impose on humans. Here, we examine how sea ice and snow cover, as well as methane emissions due to changes in permafrost, may potentially change in the future, to year 2100, and how these changes may feed back to influence the climate. Between 2010 and 2100, the annual costs from the extra warming due to a decline in albedo related to losses of sea ice and snow, plus each year's methane emissions, cumulate to a present value cost to society ranging from US$7.5 trillion to US$91.3 trillion. The estimated range reflects uncertainty associated with (1) the extent of warming-driven positive climate feedbacks from the thawing cryosphere and (2) the expected economic damages per metric ton of CO2 equivalents that will be imposed by added warming, which depend, especially, on the choice of discount rate. The economic uncertainty is much larger than the uncertainty in possible future feedback effects. Nonetheless, the frozen Arctic provides immense services to all nations by cooling the earth's temperature: the cryosphere is an air conditioner for the planet. As the Arctic thaws, this critical, climate-stabilizing ecosystem service is being lost. This paper provides a first attempt to monetize the cost of some of those lost services.

  18. Does part-time sick leave help individuals with mental disorders recover lost work capacity?

    Science.gov (United States)

    Andrén, Daniela

    2014-06-01

    This paper aims to answer the question whether combining sick leave with some hours of work can help employees diagnosed with a mental disorder (MD) increase their probability of returning to work. Given the available data, this paper analyzes the impact of part-time sick leave (PTSL) on the probability of fully recovering lost work capacity for employees diagnosed with an MD. The effects of PTSL on the probability of fully recovering lost work capacity are estimated by a discrete choice one-factor model using data on a nationally representative sample extracted from the register of the National Agency of Social Insurance in Sweden and supplemented with information from questionnaires. All individuals in the sample were 20-64 years old and started a sickness spell of at least 15 days between 1 and 16 February 2001. We selected all employed individuals diagnosed with an MD, with a final sample of 629 individuals. The results show that PTSL is associated with a low likelihood of full recovery, yet the timing of the assignment is important. PTSL's effect is relatively low (0.015) when it is assigned in the beginning of the spell but relatively high (0.387), and statistically significant, when assigned after 60 days of full-time sick leave (FTSL). This suggests efficiency improvements from assigning employees with an MD diagnosis, when possible, to PTSL. The employment gains will be enhanced if employees with an MD diagnosis are encouraged to return to work part-time after 60 days or more of FTSL.

  19. Lost in space: Onboard star identification using CCD star tracker data without an a priori attitude

    Science.gov (United States)

    Ketchum, Eleanor A.; Tolson, Robert H.

    1993-01-01

    There are many algorithms in use today which determine spacecraft attitude by identifying stars in the field of view of a star tracker. Some methods, which date from the early 1960's, compare the angular separation between observed stars with a small catalog. In the last 10 years, several methods have been developed which speed up the process and reduce the amount of memory needed, a key element to onboard attitude determination. However, each of these methods require some a priori knowledge of the spacecraft attitude. Although the Sun and magnetic field generally provide the necessary coarse attitude information, there are occasions when a spacecraft could get lost when it is not prudent to wait for sunlight. Also, the possibility of efficient attitude determination using only the highly accurate CCD star tracker could lead to fully autonomous spacecraft attitude determination. The need for redundant coarse sensors could thus be eliminated at substantial cost reduction. Some groups have extended their algorithms to implement a computation intense full sky scan. Some require large data bases. Both storage and speed are concerns for autonomous onboard systems. Neural network technology is even being explored by some as a possible solution, but because of the limited number of patterns that can be stored and large overhead, nothing concrete has resulted from these efforts. This paper presents an algorithm which, by descretizing the sky and filtering by visual magnitude of the brightness observed star, speeds up the lost in space star identification process while reducing the amount of necessary onboard computer storage compared to existing techniques.

  20. Phylogeny and History of the Lost SIV from Crab-Eating Macaques: SIVmfa.

    Science.gov (United States)

    McCarthy, Kevin R; Johnson, Welkin E; Kirmaier, Andrea

    2016-01-01

    In the 20th century, thirteen distinct human immunodeficiency viruses emerged following independent cross-species transmission events involving simian immunodeficiency viruses (SIV) from African primates. In the late 1900s, pathogenic SIV strains also emerged in the United Sates among captive Asian macaque species following their unintentional infection with SIV from African sooty mangabeys (SIVsmm). Since their discovery in the 1980s, SIVs from rhesus macaques (SIVmac) and pig-tailed macaques (SIVmne) have become invaluable models for studying HIV pathogenesis, vaccine design and the emergence of viruses. SIV isolates from captive crab-eating macaques (SIVmfa) were initially described but lost prior to any detailed molecular and genetic characterization. In order to infer the origins of the lost SIVmfa lineage, we located archived material and colony records, recovered its genomic sequence by PCR, and assessed its phylogenetic relationship to other SIV strains. We conclude that SIVmfa is the product of two cross-species transmission events. The first was the established transmission of SIVsmm to rhesus macaques, which occurred at the California National Primate Research Center in the late 1960s and the virus later emerged as SIVmac. In a second event, SIVmac was transmitted to crab-eating macaques, likely at the Laboratory for Experimental Medicine and Surgery in Primates in the early 1970s, and it was later spread to the New England Primate Research Center colony in 1973 and eventually isolated in 1986. Our analysis suggests that SIVmac had already emerged by the early 1970s and had begun to diverge into distinct lineages. Furthermore, our findings suggest that pathogenic SIV strains may have been more widely distributed than previously appreciated, raising the possibility that additional isolates may await discovery.

  1. Phylogeny and History of the Lost SIV from Crab-Eating Macaques: SIVmfa.

    Directory of Open Access Journals (Sweden)

    Kevin R McCarthy

    Full Text Available In the 20th century, thirteen distinct human immunodeficiency viruses emerged following independent cross-species transmission events involving simian immunodeficiency viruses (SIV from African primates. In the late 1900s, pathogenic SIV strains also emerged in the United Sates among captive Asian macaque species following their unintentional infection with SIV from African sooty mangabeys (SIVsmm. Since their discovery in the 1980s, SIVs from rhesus macaques (SIVmac and pig-tailed macaques (SIVmne have become invaluable models for studying HIV pathogenesis, vaccine design and the emergence of viruses. SIV isolates from captive crab-eating macaques (SIVmfa were initially described but lost prior to any detailed molecular and genetic characterization. In order to infer the origins of the lost SIVmfa lineage, we located archived material and colony records, recovered its genomic sequence by PCR, and assessed its phylogenetic relationship to other SIV strains. We conclude that SIVmfa is the product of two cross-species transmission events. The first was the established transmission of SIVsmm to rhesus macaques, which occurred at the California National Primate Research Center in the late 1960s and the virus later emerged as SIVmac. In a second event, SIVmac was transmitted to crab-eating macaques, likely at the Laboratory for Experimental Medicine and Surgery in Primates in the early 1970s, and it was later spread to the New England Primate Research Center colony in 1973 and eventually isolated in 1986. Our analysis suggests that SIVmac had already emerged by the early 1970s and had begun to diverge into distinct lineages. Furthermore, our findings suggest that pathogenic SIV strains may have been more widely distributed than previously appreciated, raising the possibility that additional isolates may await discovery.

  2. Lost productivity due to premature mortality in developed and emerging countries: an application to smoking cessation.

    Science.gov (United States)

    Menzin, Joseph; Marton, Jeno P; Menzin, Jordan A; Willke, Richard J; Woodward, Rebecca M; Federico, Victoria

    2012-06-25

    Researchers and policy makers have determined that accounting for productivity costs, or "indirect costs," may be as important as including direct medical expenditures when evaluating the societal value of health interventions. These costs are also important when estimating the global burden of disease. The estimation of indirect costs is commonly done on a country-specific basis. However, there are few studies that evaluate indirect costs across countries using a consistent methodology. Using the human capital approach, we developed a model that estimates productivity costs as the present value of lifetime earnings (PVLE) lost due to premature mortality. Applying this methodology, the model estimates productivity costs for 29 selected countries, both developed and emerging. We also provide an illustration of how the inclusion of productivity costs contributes to an analysis of the societal burden of smoking. A sensitivity analysis is undertaken to assess productivity costs on the basis of the friction cost approach. PVLE estimates were higher for certain subpopulations, such as men, younger people, and people in developed countries. In the case study, productivity cost estimates from our model showed that productivity loss was a substantial share of the total cost burden of premature mortality due to smoking, accounting for over 75 % of total lifetime costs in the United States and 67 % of total lifetime costs in Brazil. Productivity costs were much lower using the friction cost approach among those of working age. Our PVLE model is a novel tool allowing researchers to incorporate the value of lost productivity due to premature mortality into economic analyses of treatments for diseases or health interventions. We provide PVLE estimates for a number of emerging and developed countries. Including productivity costs in a health economics study allows for a more comprehensive analysis, and, as demonstrated by our illustration, can have important effects on the

  3. Effect of Diet Composition on Energy Expenditure during Weight Loss: The POUNDS LOST Study

    Science.gov (United States)

    Bray, George A.; Smith, Steven R.; DeJonge, Lilian; de Souza, Russell; Rood, Jennifer; Champagne, Catherine M.; Laranjo, Nancy; Carey, Vincent; Obarzanek, Eva; Loria, Catherine M.; Anton, Stephen D.; Ryan, Donna H.; Greenway, Frank L.; Williamson, Donald; Sacks, Frank M.

    2011-01-01

    Background Weight loss reduces energy expenditure, but the contribution of different macronutrients to this change is unclear. Hypothesis We tested the hypothesis that macronutrient composition of the diet might affect the partitioning of energy expenditure during weight loss. Design A sub-study of 99 participants from the POUNDS LOST trial had total energy expenditure (TEE) measured by doubly labeled water and resting energy expenditure (REE) measured by indirect calorimetry at baseline and repeated at 6 months in 89 participants. Participants were randomly assigned to one of 4 diets with either 15% or 25% protein and 20% or 40% fat. Results TEE and REE were positively correlated with each other and with fat free mass and body fat, at baseline and 6 months. The average weight loss of 8.1±0.65 kg (LSmean±SE) reduced TEE by 120±56 kcal/d and REE by 136±18 kcal/d. A greater weight loss at 6 months was associated with a greater decrease in TEE and REE. Participants eating the high fat diet lost significantly more fat free mass (1.52±0.55 kg) than the low fat diet group (p<0.05). Participants eating the low fat diet had significantly higher measures of physical activity than the high fat group. Conclusion A greater weight loss was associated with a larger decrease in both TEE and REE. The low fat diet was associated with significant changes in fat free body mass and energy expenditure from physical activity compared to the high fat diet. PMID:21946707

  4. Potential role of biotechnology tools for genetic improvement of “lost ...

    African Journals Online (AJOL)

    The paper considers the potential role of biotechnology applications like DNA markers in understanding the evolution, origin, distribution and diversity of fonio in Africa; somaclonal variation in generating genetic variability in fonio; and genetic transformation in circumventing fonio breeding barriers to introduce alien genes ...

  5. Evolution of Constructivism

    Science.gov (United States)

    Liu, Chu Chih; Chen, I Ju

    2010-01-01

    The contrast between social constructivism and cognitive constructivism are depicted in different ways in many studies. The purpose of this paper is to summarize the evolution of constructivism and put a focus on social constructivism from the perception of Vygotsky. This study provides a general idea of the evolution of constructivism for people…

  6. Evolution: Theory or Dogma?

    Science.gov (United States)

    Mayer, William V.

    In this paper the author examines the question of whether evolution is a theory or a dogma. He refutes the contention that there is a monolithic scientific conspiracy to present evolution as dogma and suggests that his own presentation might be more appropriately entitled "Creationism: Theory or Dogma." (PEB)

  7. Kognition, evolution og Bibel

    DEFF Research Database (Denmark)

    Jensen, Hans Jørgen Lundager

    2012-01-01

    En opfordring til, at Bibelvidneskaberne oprienterer sig i retning af aktuelle teorier om bio-kulturel evolution (Merlin Donald, aksetids-teori hos fx Robert Bellah)......En opfordring til, at Bibelvidneskaberne oprienterer sig i retning af aktuelle teorier om bio-kulturel evolution (Merlin Donald, aksetids-teori hos fx Robert Bellah)...

  8. Evolution for Young Victorians

    Science.gov (United States)

    Lightman, Bernard

    2012-01-01

    Evolution was a difficult topic to tackle when writing books for the young in the wake of the controversies over Darwin's "Origin of Species." Authors who wrote about evolution for the young experimented with different ways of making the complex concepts of evolutionary theory accessible and less controversial. Many authors depicted presented…

  9. Hydrogen evolution reaction catalyst

    Science.gov (United States)

    Subbaraman, Ram; Stamenkovic, Vojislav; Markovic, Nenad; Tripkovic, Dusan

    2016-02-09

    Systems and methods for a hydrogen evolution reaction catalyst are provided. Electrode material includes a plurality of clusters. The electrode exhibits bifunctionality with respect to the hydrogen evolution reaction. The electrode with clusters exhibits improved performance with respect to the intrinsic material of the electrode absent the clusters.

  10. Evolution, epigenetics and cooperation

    Indian Academy of Sciences (India)

    Explanations for biological evolution in terms of changes in gene frequencies refer to outcomes rather than process. Integrating epigenetic studies with older evolutionary theories has drawn attention to the ways in which evolution occurs. Adaptation at the level of the gene is givingway to adaptation at the level of the ...

  11. Circumgalactic Matter Matters in Galaxy Evolution

    Science.gov (United States)

    Werk, Jessica

    2018-01-01

    The circumgalactic medium (CGM; non-ISM gas within a galaxy virial radius) regulates the gas flows that shape the assembly and evolution of galaxies. Owing to the vastly improved capabilities in space-based UV spectroscopy with the installation of HST/COS, observations and simulations of the CGM have emerged as the new frontier of galaxy evolution studies. In the last decade, we have learned that the CGM of Milky Way mass galaxies likely contains enough material to harbor most of the metals lost in galaxy winds and to sustain star-formation for billions of years. Remarkably, this implies that most of the heavy elements on earth cycled back and forth multiple times through the Milky Way’s own CGM before the formation of the solar system. In this talk, I will describe constraints we have placed on the origin and fate of this material by studying the gas kinematics, metallicity and ionization state. I will conclude by posing several unanswered questions about the CGM that will be addressed with future survey data and hydrodynamic simulations in a cosmological context.

  12. Frequency of Lost Dogs and Cats in the United States and the Methods Used to Locate Them

    Science.gov (United States)

    Weiss, Emily; Slater, Margaret; Lord, Linda

    2012-01-01

    Simple Summary Dogs and cats are a common member of the family in homes across the US. No population-based data exist on the frequency of pets getting lost from the home and lost pets can be a source of human and animal suffering. Our primary objective was to determine the percentage of owned dogs and cats that were lost, and of these, what percentages of pets were recovered. We examined the recovery success for dogs compared to cats and the methods used as well as the relationship between lost or found pets and pet and owner demographics. While 15% of dog and cat owners lost their pets, dogs had higher recovery rates (93%) than cats (75%) as well as being returned using different search methods. Abstract A cross-sectional national random digit dial telephone interview was conducted between September and November 2010. There were 1,015 households that had owned a dog or cat within the past five years. Of these 817 households owned dogs and 506 owned cats. Fourteen percent of dogs (95% Confidence Interval (CI): 11–16%) and 15% (95% CI: 12–18%) of cats were lost in the past five years. No owner demographic variables were associated with losing a pet. Ninety three percent (95% CI: 86–97%) of dogs and 75% (95% CI: 64–85%) of cats were recovered. For dogs, searching the neighborhood and returning on their own were the most common methods of finding the dog; 14% were found through an identification tag. For cats, returning on their own was most common. Dogs were more likely than cats to be lost more than once. Cats were less likely than dogs to have any type of identification. Knowledge of the successful methods of finding dogs and cats can provide invaluable help for owners of lost pets. Since 25% of lost cats were not found, other methods of reuniting cats and their owners are needed. Collars and ID tags or humane trapping could be valuable approaches. PMID:26486923

  13. Evolution of complex dynamics

    Science.gov (United States)

    Wilds, Roy; Kauffman, Stuart A.; Glass, Leon

    2008-09-01

    We study the evolution of complex dynamics in a model of a genetic regulatory network. The fitness is associated with the topological entropy in a class of piecewise linear equations, and the mutations are associated with changes in the logical structure of the network. We compare hill climbing evolution, in which only mutations that increase the fitness are allowed, with neutral evolution, in which mutations that leave the fitness unchanged are allowed. The simple structure of the fitness landscape enables us to estimate analytically the rates of hill climbing and neutral evolution. In this model, allowing neutral mutations accelerates the rate of evolutionary advancement for low mutation frequencies. These results are applicable to evolution in natural and technological systems.

  14. Chemical evolution of galaxies

    CERN Document Server

    Matteucci, Francesca

    2012-01-01

    The term “chemical evolution of galaxies” refers to the evolution of abundances of chemical species in galaxies, which is due to nuclear processes occurring in stars and to gas flows into and out of galaxies. This book deals with the chemical evolution of galaxies of all morphological types (ellipticals, spirals and irregulars) and stresses the importance of the star formation histories in determining the properties of stellar populations in different galaxies. The topic is approached in a didactical and logical manner via galaxy evolution models which are compared with observational results obtained in the last two decades: The reader is given an introduction to the concept of chemical abundances and learns about the main stellar populations in our Galaxy as well as about the classification of galaxy types and their main observables. In the core of the book, the construction and solution of chemical evolution models are discussed in detail, followed by descriptions and interpretations of observations of ...

  15. Explaining evolution via constrained persistent perfect phylogeny

    Science.gov (United States)

    2014-01-01

    Background The perfect phylogeny is an often used model in phylogenetics since it provides an efficient basic procedure for representing the evolution of genomic binary characters in several frameworks, such as for example in haplotype inference. The model, which is conceptually the simplest, is based on the infinite sites assumption, that is no character can mutate more than once in the whole tree. A main open problem regarding the model is finding generalizations that retain the computational tractability of the original model but are more flexible in modeling biological data when the infinite site assumption is violated because of e.g. back mutations. A special case of back mutations that has been considered in the study of the evolution of protein domains (where a domain is acquired and then lost) is persistency, that is the fact that a character is allowed to return back to the ancestral state. In this model characters can be gained and lost at most once. In this paper we consider the computational problem of explaining binary data by the Persistent Perfect Phylogeny model (referred as PPP) and for this purpose we investigate the problem of reconstructing an evolution where some constraints are imposed on the paths of the tree. Results We define a natural generalization of the PPP problem obtained by requiring that for some pairs (character, species), neither the species nor any of its ancestors can have the character. In other words, some characters cannot be persistent for some species. This new problem is called Constrained PPP (CPPP). Based on a graph formulation of the CPPP problem, we are able to provide a polynomial time solution for the CPPP problem for matrices whose conflict graph has no edges. Using this result, we develop a parameterized algorithm for solving the CPPP problem where the parameter is the number of characters. Conclusions A preliminary experimental analysis shows that the constrained persistent perfect phylogeny model allows to

  16. Statistical behavior of time dynamics evolution of HIV infection

    Science.gov (United States)

    González, Ramón E. R.; Santos, Iury A. X.; Nunes, Marcos G. P.; de Oliveira, Viviane M.; Barbosa, Anderson L. R.

    2017-09-01

    We use the tools of the random matrix theory (RMT) to investigate the statistical behavior of the evolution of human immunodeficiency virus (HIV) infection. By means of the nearest-neighbor spacing distribution we have identified four distinct regimes of the evolution of HIV infection. We verified that at the beginning of the so-called clinical latency phase the concentration of infected cells grows slowly and evolves in a correlated way. This regime is followed by another one in which the correlation is lost and that in turn leads the system to a regime in which the increase of infected cells is faster and correlated. In the final phase, the one in which acquired immunodeficiency syndrome (AIDS) is stablished, the system presents maximum correlation as demonstrated by GOE distribution.

  17. Tyrannosauroid integument reveals conflicting patterns of gigantism and feather evolution.

    Science.gov (United States)

    Bell, Phil R; Campione, Nicolás E; Persons, W Scott; Currie, Philip J; Larson, Peter L; Tanke, Darren H; Bakker, Robert T

    2017-06-01

    Recent evidence for feathers in theropods has led to speculations that the largest tyrannosaurids, including Tyrannosaurus rex , were extensively feathered. We describe fossil integument from Tyrannosaurus and other tyrannosaurids ( Albertosaurus, Daspletosaurus, Gorgosaurus and Tarbosaurus ), confirming that these large-bodied forms possessed scaly, reptilian-like skin. Body size evolution in tyrannosauroids reveals two independent occurrences of gigantism; specifically, the large sizes in Yutyrannus and tyrannosaurids were independently derived. These new findings demonstrate that extensive feather coverings observed in some early tyrannosauroids were lost by the Albian, basal to Tyrannosauridae. This loss is unrelated to palaeoclimate but possibly tied to the evolution of gigantism, although other mechanisms exist. © 2017 The Author(s).

  18. Three-dimensional, nonlinear evolution of the Rayleigh--Taylor instability of a thin layer

    International Nuclear Information System (INIS)

    Manheimer, W.; Colombant, D.; Ott, E.

    1984-01-01

    A numerical simulation scheme is developed to examine the nonlinear evolution of the Rayleigh--Taylor instability of a thin sheet in three dimensions. It is shown that the erosion of mass at the top of the bubble is approximately as described by two-dimensional simulations. However, mass is lost into spikes more slowly in three-dimensional than in two-dimensional simulations

  19. The involvement of beta-1,4-galactosyltransferase and N-acetylglucosamine residues in fertilization has been lost in the horse

    Directory of Open Access Journals (Sweden)

    Magistrini Michèle

    2008-11-01

    Full Text Available Abstract Background In human and rodents, sperm-zona pellucida binding is mediated by a sperm surface Galactosyltransferase that recognizes N-Acetylglucosamine residues on a glycoprotein ZPC. In large domestic mammals, the role of these molecules remains unclear: in bovine, they are involved in sperm-zona pellucida binding, whereas in porcine, they are not necessary. Our aim was to clarify the role of Galactosyltransferase and N-Acetylglucosamine residues in sperm-zona pellucida binding in ungulates. For this purpose, we analyzed the mechanism of sperm-zona pellucida interaction in a third ungulate: the horse, since the Galactosyltransferase and N-Acetylglucosamine residues have been localized on equine gametes. Methods We masked the Galactosyltransferase and N-Acetylglucosamine residues before the co-incubation of gametes. Galactosyltransferase was masked either with an anti-Galactosyltransferase antibody or with the enzyme substrate, UDP Galactose. N-Acetylglucosamine residues were masked either with a purified Galactosyltransferase or with an anti-ZPC antibody. Results and discussion The number of spermatozoa bound to the zona pellucida did not decrease after the masking of Galactosyltransferase or N-Acetylglucosamine. So, these two molecules may not be necessary in the mechanism of in vitro sperm-zona pellucida interaction in the horse. Conclusion The involvement of Galactosyltransferase and N-Acetylglucosamine residues in sperm-zona pellucida binding may have been lost during evolution in some ungulates, such as porcine and equine species.

  20. Influence of pores on crack initiation in monotonic tensile and cyclic loadings in lost foam casting A319 alloy by using 3D in-situ analysis

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Long, E-mail: longwang_calt@163.com [Univ. Lille, CNRS, Centrale Lille, Arts et Metiers Paris tech, FRE 3723 – LML – Laboratoire de Mecanique de Lille, F-59000 Lille (France); Limodin, Nathalie; El Bartali, Ahmed; Witz, Jean-François; Seghir, Rian [Univ. Lille, CNRS, Centrale Lille, Arts et Metiers Paris tech, FRE 3723 – LML – Laboratoire de Mecanique de Lille, F-59000 Lille (France); Buffiere, Jean-Yves [Laboratoire Matériaux, Ingénierie et Sciences (MATEIS), CNRS UMR5510, INSA-Lyon, 20 Av. Albert Einstein, 69621 Villeurbanne (France); Charkaluk, Eric [Univ. Lille, CNRS, Centrale Lille, Arts et Metiers Paris tech, FRE 3723 – LML – Laboratoire de Mecanique de Lille, F-59000 Lille (France)

    2016-09-15

    Lost Foam Casting (LFC) process is replacing the conventional gravity Die Casting (DC) process in automotive industry for the purpose of geometry optimization, cost reduction and consumption control. However, due to lower cooling rate, LFC produces in a coarser microstructure that reduces fatigue life. In order to study the influence of the casting microstructure of LFC Al-Si alloy on damage micromechanisms under monotonic tensile loading and Low Cycle Fatigue (LCF) at room temperature, an experimental protocol based on the three dimensional (3D) in-situ analysis has been set up and validated. This paper focuses on the influence of pores on crack initiation in monotonic and cyclic tensile loadings. X-ray Computed Tomography (CT) allowed the microstructure of material being characterized in 3D and damage evolution being followed in-situ also in 3D. Experimental and numerical mechanical fields were obtained by using Digital Volume Correlation (DVC) technique and Finite Element Method (FEM) simulation respectively. Pores were shown to have an important influence on strain localization as large pores generate enough strain localization zones for crack initiation both in monotonic tensile and cyclic loadings.

  1. Influence of pores on crack initiation in monotonic tensile and cyclic loadings in lost foam casting A319 alloy by using 3D in-situ analysis

    International Nuclear Information System (INIS)

    Wang, Long; Limodin, Nathalie; El Bartali, Ahmed; Witz, Jean-François; Seghir, Rian; Buffiere, Jean-Yves; Charkaluk, Eric

    2016-01-01

    Lost Foam Casting (LFC) process is replacing the conventional gravity Die Casting (DC) process in automotive industry for the purpose of geometry optimization, cost reduction and consumption control. However, due to lower cooling rate, LFC produces in a coarser microstructure that reduces fatigue life. In order to study the influence of the casting microstructure of LFC Al-Si alloy on damage micromechanisms under monotonic tensile loading and Low Cycle Fatigue (LCF) at room temperature, an experimental protocol based on the three dimensional (3D) in-situ analysis has been set up and validated. This paper focuses on the influence of pores on crack initiation in monotonic and cyclic tensile loadings. X-ray Computed Tomography (CT) allowed the microstructure of material being characterized in 3D and damage evolution being followed in-situ also in 3D. Experimental and numerical mechanical fields were obtained by using Digital Volume Correlation (DVC) technique and Finite Element Method (FEM) simulation respectively. Pores were shown to have an important influence on strain localization as large pores generate enough strain localization zones for crack initiation both in monotonic tensile and cyclic loadings.

  2. ‘Everything is autobiographical’: Hans-Ulrich Treichel’s idiolect in Lost (1999

    Directory of Open Access Journals (Sweden)

    Philip van der Merwe

    2014-12-01

    Full Text Available Joachim Dicks writes in his review on Hans-Ulrich Treichel’s latest novel, Frühe Störung,that the author shows continuity by having developed in all of his books a unique and unmistakeable style that he calls ‘the so-called Treichel sound’. Treichel’s style, tone and mixture of thematic concerns in all of his eleven works of prose from Von Leib und Seele: Berichte up to Frühe Störung are indeed recognisable as distinctively Treichel, but has remained an unexplored terrain. The question therefore arises: What is the nature of the so-called ‘Treichel sound’ or his idiolect? Lost is a case in point with regard to Treichel’s idiolect: the narration includes factual historical and autobiographic information that represents both an ‘official life’ and a ‘carnival’, i.e. his representations of lives are determined by two aspects of theworld: the aspect of the piety of seriousness and by the aspect of laughter. This article firstly focuses on the theoretical possibility of using ‘serious’ factual autobiographic and historical information in combination with humour. The most prominent idiolectic traits of Treichel’soeuvre are then introduced, also in order to provide a context for the following discussion of Lost. Here it becomes apparent that Treichel’s humour has a tragicomical and derisive effect with regard to the narrator’s depiction of his childhood, family experiences and his cultural context. The microcosmic family context and the macrocosmic national and international contexts as they were formed because of the Second World War has lead to a loss of the narrator’s identity. The result of Treichel’s manner of dealing with serious contents that includes humour is the creation of a self-concept that can be described as self-exploratory,honest or confessional, self-centred, humorous and critical of German society - and these are also key features of Treichel’s idiolect. This article thus argues that the

  3. The High Court's lost chance in medical negligence: Tabet v Gett (2010) 240 CLR 537.

    Science.gov (United States)

    Faunce, Thomas; McEwan, Alexandra

    2010-12-01

    In 2010 the High Court of Australia in Tabet v Gett (2010) 240 CLR 537 determined an appeal in a medical negligence case concerning a six-year-old girl who had presented to a major paediatric hospital with symptoms over several weeks of headaches and vomiting after a recent history of chicken pox. The differential diagnosis was varicella, meningitis or encephalitis and two days later, after she deteriorated neurologically, she received a lumbar puncture. Three days later she suffered a seizure and irreversible brain damage. A CT scan performed at that point showed a brain tumour. As Australia does not have a no-fault system providing compensation to cover the long-term care required for such a condition, the girl (through her parents and lawyers) sued her treating physician. She alleged that, because a cerebral CT scan was not performed when clinically indicated after the diagnosis of meningitis or encephalitis and before the lumbar puncture, she had "lost the chance" to have her brain tumour treated before she sustained permanent brain damage. She succeeded at first instance, but lost on appeal. The High Court also rejected her claim, holding unanimously that there were no policy reasons to allow recovery of damages based on possible (less than 50%) "loss of a chance" of a better medical outcome. The court held that the law of torts in Australia required "all or nothing" proof that physical injury was caused or contributed to by a negligent party. The High Court, however, did not exclude loss of chance as forming the substance of a probable (greater than 50%) claim in medical negligence in some future case. In the meantime, patients injured in Australia as a result of possible medical negligence (particularly in the intractable difficult instances of late diagnosis) must face the injustice of the significant day-to-day care needs of victims being carried by family members and the taxpayer-funded public hospital system. The High Court in Tabet v Gett again provides

  4. Discovery of the Lost Star Catalog of Hipparchus on the Farnese Atlas

    Science.gov (United States)

    Schaefer, B. E.

    2004-12-01

    Hipparchus was the greatest astronomer in Antiquity, with part of his reputation being based on his creation of the first star catalog around 129 BC. His star catalog has been since lost, although a few partial star positions are recorded in his only surviving work, the Commentary. Independently, a late Roman statue called the Farnese Atlas (now in Naples) has been known since the Middle Ages which records ancient Greek constellations. This marble statue shows the Titan Atlas kneeling on one knee while hold a large globe (65 cm in diameter) on one shoulder. This globe records 41 constellations accurately placed against a grid of reference circles, including the equator, tropics, colures, Arctic circle, and Antarctic circle. As the constellation positions shift over time (due to precession as discovered by Hipparchus), the position of the constellations on the Titan's globe will reveal the date of observations as ultimately used by the sculptor. Prior brief work on the globe has resulted in dates spread out over six centuries, with recent reviews only concluding that a thorough study is desperately needed. To fill this need, I have taken photographs appropriate for photogrammetry and have measured the positions of 70 points in the constellation figures and transformed these into RA and DEC in the globe's reference frame. A chi-square analysis then shows the date of the constellations to be 125 BC with a one-sigma uncertainty of 55 years. This date points directly at Hipparchus as being the observer and it strongly excludes all candidates that have been proposed over the past century (Aratus at c. 275 BC, Eudoxus at c. 366 BC, the original Assyrian observer at c. 1130 BC, and Ptolemy at AD 128). In addition, a very detailed comparison of the constellation figures and symbols on the Atlas' globe has been made with Hipparchus' Commentary, Aratus' (and Eudoxus') Phaenomena, Eratosthenes' Catasterismi, and Ptolemy's Almagest. I find essentially perfect agreement with

  5. Chemistry of a serpentinization-controlled hydrothermal system at the Lost City hydrothermal vent field

    Science.gov (United States)

    Ludwig, K. A.; Kelley, D. S.; Butterfield, D. A.; Nelson, B. K.; Karson, J. A.

    2003-12-01

    The Lost City Hydrothermal Field (LCHF), at 30° N near the Mid-Atlantic Ridge, is an off-axis, low temperature, high-pH, ultramafic-hosted vent system. Within the field, carbonate chimneys tower up to 60 m above the seafloor, making them the tallest vent structures known. The chemistry of the vent structures and fluids at the LCHF is controlled by reactions between seawater and ultramafic rocks beneath the Atlantis massif. Mixing of warm alkaline vent fluids with seawater causes precipitation of calcium carbonate and growth of the edifaces, which range from tall, graceful pinnacles to fragile flanges and colloform deposits. Geochemical and petrological analyses of the carbonate rocks reveal distinct differences between the active and extinct structures. Actively venting chimneys and flanges are extremely porous, friable formations composed predominantly of aragonite and brucite. These structures provide important niches for well-developed microbial communities that thrive on and within the chimney walls. Some of the active chimneys may also contain the mineral ikaite, an unstable, hydrated form of calcium carbonate. TIMS and ICP-MS analyses of the carbonate chimneys show that the most active chimneys have low Sr isotope values and that they are low in trace metals (e.g., Mn, Ti, Pb). Active structures emit high-pH, low-Mg fluids at 40-90° C. The fluids also have low Sr values, indicating circulation of hydrothermal solutions through the serpentinite bedrock beneath the field. In contrast to the active structures, extinct chimneys are less porous, are well lithified, and they are composed predominantly of calcite that yields Sr isotopes near seawater values. Prolonged lower temperature seawater-hydrothermal fluid interaction within the chimneys results in the conversion of aragonite to calcite and in the enrichment of some trace metals (e.g., Mn, Ti, Co, Zn). It also promotes the incorporation of foraminifera within the outer, cemented walls of the carbonate

  6. Development and evolution of the unique cetacean dentition

    Directory of Open Access Journals (Sweden)

    Brooke A. Armfield

    2013-02-01

    Full Text Available The evolutionary success of mammals is rooted in their high metabolic rate. A high metabolic rate is sustainable thanks to efficient food processing and that in turn is facilitated by precise occlusion of the teeth and the acquisition of rhythmic mastication. These major evolutionary innovations characterize most members of the Class Mammalia. Cetaceans are one of the few groups of mammals in which precise occlusion has been secondarily lost. Most toothed whales have an increased number of simple crowned teeth that are similar along the tooth row. Evolution toward these specializations began immediately after the time cetaceans transitioned from terrestrial-to-marine environments. The fossil record documents the critical aspects of occlusal evolution of cetaceans, and allows us to pinpoint the evolutionary timing of the macroevolutionary events leading to their unusual dental morphology among mammals. The developmental controls of tooth differentiation and tooth number have been studied in a few mammalian clades, but nothing is known about how these controls differ between cetaceans and mammals that retain functional occlusion. Here we show that pigs, a cetacean relative with regionalized tooth morphology and complex tooth crowns, retain the typical mammalian gene expression patterns that control early tooth differentiation, expressing Bmp4 in the rostral (mesial, anterior domain of the jaw, and Fgf8 caudally (distal, posterior. By contrast, dolphins have lost these regional differences in dental morphology and the Bmp4 domain is extended into the caudal region of the developing jaw. We hypothesize that the functional constraints underlying mammalian occlusion have been released in cetaceans, facilitating changes in the genetic control of early dental development. Such major developmental changes drive morphological evolution and are correlated with major shifts in diet and food processing during cetacean evolution.

  7. Procedures for brachytherapy sources lost in a radiotherapy department; Protocolo para fontes de braquiterapia extraviadas no ambiente hospitalar

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, Adelaide de [Sao Paulo Univ., Ribeirao Preto, SP (Brazil). Faculdade de Filosofia, Ciencias e Letras

    1997-12-31

    Brachytherapy sources are easily lost in a Radiotherapy Department owing to unexpected behaviour of the patient and/or inattention of the people in charge of the sources. This work reports a protocol to be used when brachytherapy sources are lost and it was based on the search of three sealed sources of Cesium 137 with activity of 37 x 10{sup 7} Bq, removed by a patient from a conventional afterloading intra-uterine system (Henscke). (author) 5 refs., 3 figs.; e-mail: dalmeida at biomag.ffclrp.usp.br

  8. Lost life years due to premature deaths caused by diseases of the digestive system in Poland in 2013

    Science.gov (United States)

    Paciej, Paulina; Ciabiada, Beata; Maniecka-Bryła, Irena

    In order to evaluate the health status of a population, besides indicators measuring the incidence of diseases and deaths, potential measures are becoming more frequently used, ie. measures that take into account life-time potential of the individuals in the population. They can particularly by applied to analyse the problem of premature mortality, which is measured by lost life years. The aim of the study was to evaluate life years lost due to diseases of digestive system in Polish population in 2013. The study was based on a dataset containing 387,312 death certificates of Poles who died in 2013, provided by the Central Statistical Office in Poland. Data on deaths caused by diseases of digestive system (K00-K93 by ICD-10) were used in the study – that were 16,543 records (4.3% of all the deaths). Lost life years were assessed with the measures: SEYLL (Standard Expected Years of Life Lost), SEYLLp (Standard Expected Years of Life Lost per living person), SEYLLd (Standard Expected Years of Life Lost per death). In the analysed year among men there were 9,275 deaths caused by diseases of digestive system and in women 7,268 deaths. SEYLL in the group of men amounted to 102 230.7 and in the group of women it was 53,475.5. The number of lost life years calculated per 10 000 male inhabitants was 54.9, and for 10,000 females it was 26.9. The highest share in lost life years had alcoholic liver disease (SEYLLp for men – 20.87, for women – 6.1), fibrosis and cirrhosis of the liver (SEYLLp for men- 9.7, for women- 5.6) and acute pancreatitis (SEYLLp for men – 5.3, for women – 2.1). The results of the study indicate that diseases of digestive system have an important contribution to the loss of life-time potential in Polish population (6.6% of all SEYLL in 2013). The dominant role in this class of diseases played alcoholic liver disease – K70, fibrosis and cirrhosis of the liver – K74 and acute pancreatitis – K85.

  9. Obesity as a Possible Risk Factor for Lost-time Injury in Registered Nurses: A Literature Review

    OpenAIRE

    Jordan, Gillian; Nowrouzi-Kia, Behnam; Gohar, Basem; Nowrouzi, Behdin

    2015-01-01

    Time-loss injuries are still a major occurrence in Canada, injuring thousands of Canadian workers each year. With obesity rates on the rise across the country, as well as around the world, it is important that the possible effects of obesity in the workplace be fully understood, especially those effects linked to lost-time injuries. The aim of this paper was to evaluate predictors of workplace lost-time injuries and how they may be related to obesity or high body mass index by examining facto...

  10. Chromosomal Evolution in Chiroptera.

    Science.gov (United States)

    Sotero-Caio, Cibele G; Baker, Robert J; Volleth, Marianne

    2017-10-13

    Chiroptera is the second largest order among mammals, with over 1300 species in 21 extant families. The group is extremely diverse in several aspects of its natural history, including dietary strategies, ecology, behavior and morphology. Bat genomes show ample chromosome diversity (from 2n = 14 to 62). As with other mammalian orders, Chiroptera is characterized by clades with low, moderate and extreme chromosomal change. In this article, we will discuss trends of karyotypic evolution within distinct bat lineages (especially Phyllostomidae, Hipposideridae and Rhinolophidae), focusing on two perspectives: evolution of genome architecture, modes of chromosomal evolution, and the use of chromosome data to resolve taxonomic problems.

  11. Chromosomal Evolution in Chiroptera

    Directory of Open Access Journals (Sweden)

    Cibele G. Sotero-Caio

    2017-10-01

    Full Text Available Chiroptera is the second largest order among mammals, with over 1300 species in 21 extant families. The group is extremely diverse in several aspects of its natural history, including dietary strategies, ecology, behavior and morphology. Bat genomes show ample chromosome diversity (from 2n = 14 to 62. As with other mammalian orders, Chiroptera is characterized by clades with low, moderate and extreme chromosomal change. In this article, we will discuss trends of karyotypic evolution within distinct bat lineages (especially Phyllostomidae, Hipposideridae and Rhinolophidae, focusing on two perspectives: evolution of genome architecture, modes of chromosomal evolution, and the use of chromosome data to resolve taxonomic problems.

  12. Contemporary evolution strategies

    CERN Document Server

    Bäck, Thomas; Krause, Peter

    2013-01-01

    Evolution strategies have more than 50 years of history in the field of evolutionary computation. Since the early 1990s, many algorithmic variations of evolution strategies have been developed, characterized by the fact that they use the so-called derandomization concept for strategy parameter adaptation. Most importantly, the covariance matrix adaptation strategy (CMA-ES) and its successors are the key representatives of this group of contemporary evolution strategies. This book provides an overview of the key algorithm developments between 1990 and 2012, including brief descriptions of the a

  13. Weathering and landscape evolution

    Science.gov (United States)

    Turkington, Alice V.; Phillips, Jonathan D.; Campbell, Sean W.

    2005-04-01

    In recognition of the fundamental control exerted by weathering on landscape evolution and topographic development, the 35th Binghamton Geomorphology Symposium was convened under the theme of Weathering and Landscape Evolution. The papers and posters presented at the conference imparted the state-of-the-art in weathering geomorphology, tackled the issue of scale linkage in geomorphic studies and offered a vehicle for interdisciplinary communication on research into weathering and landscape evolution. The papers included in this special issue are encapsulated here under the general themes of weathering mantles, weathering and relative dating, weathering and denudation, weathering processes and controls and the 'big picture'.

  14. Dual phase evolution

    CERN Document Server

    Green, David G; Abbass, Hussein A

    2014-01-01

    This book explains how dual phase evolution operates in all these settings and provides a detailed treatment of the subject. The authors discuss the theoretical foundations for the theory, how it relates to other phase transition phenomena and its advantages in evolutionary computation and complex adaptive systems. The book provides methods and techniques to use this concept for problem solving. Dual phase evolution concerns systems that evolve via repeated phase shifts in the connectivity of their elements. It occurs in vast range of settings, including natural systems (species evolution, landscape ecology, geomorphology), socio-economic systems (social networks) and in artificial systems (annealing, evolutionary computing).

  15. Mass loss in early stages of stellar evolution

    International Nuclear Information System (INIS)

    Dearborn, D.S.P.; Kozlowski, M.; Schramm, D.

    1976-01-01

    It is known that stars lose mass between their birth on the main sequence and their death as white dwarfs, or as neutron stars or black holes for more massive stars. Solar wind considerations indicate that not all of the mass loss occurs in a 'last gasp' to form a planetary nebula. Mass loss has be observed in O-B stars and in red giants, but the mass loss observed in these stages do not appear sufficient to account for all the loss required for stars to become white dwarfs. The problem is at what stages and in what manner the excess mass is lost. Suggestions have tended to favour He flashes for stars with M < 2.25 M. and possibly double shell instability flashes for stars in the range from 2.25 M. to 8 M. Although is is possible that significant mass is lost during these stages, there appears to be no quantitative support for this suggestion, and in particular none for the He flash. It is shown here that there is increasing evidence for substantial mass loss during the immediate post main sequence stages when the star is moving from the main sequence to the giant branch. Mass loss at these early stages of evolution may have implications on the subsequent evolution of the star and the amount of nuclearly processed material that is ejected into the interstellar-medium. The behaviour of Arcturus is discussed in these connections. (U.K.)

  16. Milton’s Pro-Feminist Presentation of Eve in Paradise Lost

    Directory of Open Access Journals (Sweden)

    Abdullah F. Al-Badarneh

    2014-07-01

    Full Text Available This paper absolves John Milton from any critical and feminist accusation of being anti-feminist in Paradise Lost. Such defense of Milton is based on the close reading and analysis of the passages that focus on Adam and Eve in the text. This study highlights Milton’s modern view of women as independent, free, and responsible. It also presents his iconoclasm in representing women as leaders and initiative takers when decision is to be taken. This study shows Milton reversing traditional gender roles through the relationship of Adam and Eve. In addition, one can find a modern emphasis on the principles of equality, democracy, dialogue, freedom, and free will available in the poem and designed in a way that serves Eve’s rights in comparison with Adam’s. Therefore, my voice in defending Milton joins the cohort of critics who believe of Milton’s wide perspective of pro-feminism and not a person of misogyny.

  17. Masculinity lost: a systematic review of qualitative research on men with spinal cord injury.

    Science.gov (United States)

    Nolan, M

    2013-08-01

    Systematic, thematic, narrative review of qualitative literature. To systematically review qualitative research that explores the impact of spinal cord injury (SCI) on the gendered experience of men with SCI. A systematic search of databases and hand search of relevant journals to provide a thematic narrative review of articles, providing sufficient depth of information, relevant participant quotes and phenomenological insight into the gendered experience of men with SCI. Identified studies are summarised and common themes extracted and discussed in relation to relevant literature on masculinity, disability and health. Eight papers, representing four separate studies met the review criteria for relevance and rigour. Three broad, overlapping themes describing the gendered experience of men with SCI were identified: 'lost masculinity', outlining the impact of SCI on traditional masculine identity, 'fighting back', describing the battle to regain and reclaim masculinity and integrate disability into a revised identity and 'beyond hegemony', referring to possibilities beyond adherence to traditional masculine scripts. This review demonstrates a lack of explicit focus on men as gendered beings within the available qualitative literature. The findings are consistent with the limited quantitative data, which indicates that grappling with altered gendered identity is a central feature of life for men with SCI. Masculine identity emerges in this review as vulnerable to the impact of SCI, and given the strong links identified between masculinity, rehabilitation and health, as an aspect of experience that warrants more attention than it has received.

  18. Projected fantasies and the political process: toward understanding why Hillary lost.

    Science.gov (United States)

    Kibel, Howard D

    2012-01-01

    The author explores the events involved in the Democratic Party primary campaign of 2007-2008. Well before the campaign began, Senator Hillary Rodham Clinton was seen as the odds-on favorite to capture the nomination. But, that did not happen. Not only did she trail a relatively politically unknown, but she lost favor with many of those who would normally have supported her, such as advocates of gender progressivism, including many women. The author attempts to explain what happened by examining voter behavior, large group identity and its corollary of political identity, and the relation of large groups to leaders. Noting the effect of the sexual scandals during the Presidency of her husband, the author postulates that particular scenarios that have been repetitive throughout history, in art and literature, and reflected in mythology were graphed onto the perception of the Clintons. These narratives, much like Jung's archetypes, have evocative potential. Freud's early formulation of oedipal betrayal is used to explain the dynamics of infidelity and how that weakened Senator Clinton in the eyes of the public.

  19. Lost in translation?: Comparing three Scandinavian translations of the Beliefs about Medicines Questionnaire.

    Science.gov (United States)

    Granas, Anne Gerd; Nørgaard, Lotte Stig; Sporrong, Sofia Kälvemark

    2014-08-01

    The "Beliefs about Medicines Questionnaire" (BMQ) assess balance of necessity and concern of medicines. The BMQ has been translated from English to many languages. However, the original meaning of statements, such as "My medicine is a mystery to me", may be lost in translation. The aim of this study is to compare three Scandinavian translations of the BMQ. (1) How reliable are the translations? (2) Are they still valid after translation? Translated Norwegian, Swedish and Danish versions of the BMQ were scrutinized by three native Scandinavian researchers. Linguistic differences and ambiguities in the 5-point Likert scale and the BMQ statements were compared. In the Scandinavian translations, the Likert scale expanded beyond the original version at one endpoint (Swedish) or both endpoints (Danish). In the BMQ statements, discrepancies ranged from smaller inaccuracies toward completely different meaning. Some dissimilarities reflect different cultural beliefs about medicines. When translating questionnaires, bilingual researchers should scrutinize translations across similar languages to address content validity across different countries and languages. Our findings are of relevance to other BMQ translations in non-English countries, as direct comparisons between different translations might not be reliable or valid. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  20. [An Epistemological Analysis of] Predestination and Free-Will in John Milton’s Paradise Lost

    Directory of Open Access Journals (Sweden)

    Sayyed Vahid Abtahi

    2014-05-01

    Full Text Available Paradise Lost by John Milton is one of the most important literary works of the seventeenth century. In this epic in verse Milton, by displaying a portrait that combines Greek Mythology and Christian teachings, seeks to elucidate Divine Providence and man’s relation with God’s decree. He puts together Divine will-power and human determination to make the meaning understood of the Man’s Fall. Milton first adhered to Calvin’s school with regard to determinism and free will but afterward he turned to Arminianism.  In Calvinism, it is believed that man’s fall has been registered in God’s eternal knowledge, that is, the Fall was to happen according to the will of God from the beginning. Therefore, both the prosperity and salvation of humankind are dependent upon God’s decision. However, in the Arminius’ school, it is believed that man is free and has authority to either accept or reject the Divine favor. From Milton’s viewpoint, predestination is God’s foreknowledge about the occurrence of events not about the creation of events. Consequently, if we consider man’s will-power on the basis of this belief of Milton, man may also become possessed of Divine decision (Divine will-power.

  1. The three constituencies of the state: why the state has lost unifying energy.

    Science.gov (United States)

    King, Desmond; Le Galès, Patrick

    2017-11-01

    We address resurgent populism by examining structural processes of state transformation in the UK, the US and France. Scholars stress the 'unifying energy of the state', a set of institutions and policies capable of limiting inequalities and defending legal regimes. One characteristic of modern Western statehood were packages of policies designed to integrate social groups and territories in part by ensuring common standards of provision and social citizenship across the nation state. This echoes James Scott's critical analysis of the modernist project of the state (1998). This 'unifying energy' had different origins including nationalist movements, combatting external influence or powers, war, and preparing citizens for the rigours of industrialization. Overcoming class differences and territorial differences (including cultural, social and economic differences) was a major source of mobilization to feed this 'unifying energy of the state' in France, Italy or Spain for instance. Political and cultural identities are related in significant part to respective nation states. We argue that this 'unifying energy' was an essential component of statehood in Europe and in the US. It is now largely lost. We explain why and the significance of its displacement. © London School of Economics and Political Science 2017.

  2. On 'lost' indigenous etymological origins with the specific case of the name Ameiva.

    Science.gov (United States)

    Angeli, Nicole Frances

    2018-01-01

    Modern biology builds upon the historic exploration of the natural world. Recognizing the origin of a species' name is one path to honor the historic exploration and description of the natural world and the indigenous peoples that lived closely with organisms prior to their description. While digitization of historic papers catalogued in databases such as the Biodiversity Heritage Library (BHL) allows for searching of the first use and origin of names, the rapid pace of taxonomic publishing can occlude a thorough search for etymologies. The etymological origin of the genus name Ameiva is one such case; while unattributed in multiple recent works, it is of Tupí language origin. The first description was in the Historiae Rerum Naturalium Brasiliae by George Marcgrave (1648). Ameiva was the name used by Marcgrave's Amerindian hosts in 17 th century Dutch Brazil, where local people spoke the now extinct language Tupí. The Tupí origin was not lost, however, until as recently as the 2000s. Herein, the pre- and post-Linnaean use of the name Ameiva is traced and when the name is attributed to the Tupí language and to Marcgrave through time it is noted. The opportunity to discover and/or recover etymological origins, especially names from extinct and indigenous languages, provides insight into the early Western sciences. Careful study of etymology by naturalists is consistent with the idea that science is an evolving process with many predecessors to appreciate.

  3. Can polar bears use terrestrial foods to offset lost ice-based hunting opportunities?

    Science.gov (United States)

    Rode, Karyn D.; Robbins, Charles T.; Nelson, Lynne; Amstrup, Steven C.

    2015-01-01

    Increased land use by polar bears (Ursus maritimus) due to climate-change-induced reduction of their sea-ice habitat illustrates the impact of climate change on species distributions and the difficulty of conserving a large, highly specialized carnivore in the face of this global threat. Some authors have suggested that terrestrial food consumption by polar bears will help them withstand sea-ice loss as they are forced to spend increasing amounts of time on land. Here, we evaluate the nutritional needs of polar bears as well as the physiological and environmental constraints that shape their use of terrestrial ecosystems. Only small numbers of polar bears have been documented consuming terrestrial foods even in modest quantities. Over much of the polar bear's range, limited terrestrial food availability supports only low densities of much smaller, resident brown bears (Ursus arctos), which use low-quality resources more efficiently and may compete with polar bears in these areas. Where consumption of terrestrial foods has been documented, polar bear body condition and survival rates have declined even as land use has increased. Thus far, observed consumption of terrestrial food by polar bears has been insufficient to offset lost ice-based hunting opportunities but can have ecological consequences for other species. Warming-induced loss of sea ice remains the primary threat faced by polar bears.

  4. Newspaper media reporting of motor vehicle crashes in Singapore: an opportunity lost for injury prevention education?

    Science.gov (United States)

    Heng, Kenneth W J; Vasu, Alicia

    2010-06-01

    Newspaper media advocacy can help steer public attention away from motor vehicle crash (MVC) injuries as a personal problem to that of a social and public health issue. If used properly, newspaper media is potentially a powerful mass educator on MVC prevention. However, there is often a conflict of interest in which newspapers, in an attempt to boost readership and revenue, may over-emphasize and sensationalize the human-interest aspect of an MVC story. The aim of this study is to examine newspaper articles of MVCs in Singapore to assess how our newspaper media coverage portray MVCs and identify factors that mitigate injury and educate the public on injury prevention measures. Details of the MVC were extracted from 12 months of newspaper coverage in Singapore. Two independent coders were used to establish inter-rater reliability. From 1 January to 31 December 2007, 201 articles about MVCs were published. About 74.1% of articles assigned blame to a particular road user, negligence on either road user was implied in 56.7% of articles, and road safety messages were mentioned in 8% of the articles. The mainstream communication tone used was positive for law enforcement (71.1%) and neutral towards injury prevention or road safety messages (89.1%). Newspaper media reporting of MVCs in Singapore generally does not include injury prevention messages or highlight injury-mitigating measures. This is a lost opportunity for public education. Collaboration between public health practitioners and newspaper media is required to address this issue.

  5. The underwater installation of a drained geomembrane system on Lost Creek Dam

    International Nuclear Information System (INIS)

    Onken, S.; Harlan, R.C.; Wilkes, J.; Vaschetti, G.

    1998-01-01

    Lost Creek Dam was constructed in California around 1923. It is a 122 foot high concrete arch dam with a crest elevation of 3,287 feet and a crest length of 490 feet. Over the years, the dam and the condition of the concrete face have deteriorated. The concrete is porous and seeps water along the entire downstream face. In winter, the seeping water freezes, penetrates the concrete and causes expansion and spalling of the concrete surface. In some places, the concrete has very low strength to a depth of a foot or more, rendering the dam only marginally safe. Seven mitigative measures were identified as possible solutions to the problem. It was determined that the seepage of the water through the concrete dam could be stopped with the installation of a geomembrane to the upstream face. This paper describes the unique underwater installation of a drained geomembrane system on the concrete face of the dam. This was the first ever installation of a drained geomembrane system on an entire dam using divers. Monitoring will determine the success of the project, and whether the seepage of the water through the porous concrete had been reduced sufficiently to stop the deterioration of the concrete on the downstream face. 2 refs., 12 figs

  6. Optimization in Fuzzy Economic Order Quantity (FEOQ Model with Deteriorating Inventory and Units Lost

    Directory of Open Access Journals (Sweden)

    Monalisha Pattnaik

    2014-09-01

    Full Text Available Background: This model presents the effect of deteriorating items in fuzzy optimal instantaneous replenishment for finite planning horizon. Accounting for holding cost per unit per unit time and ordering cost per order have traditionally been the case of modeling inventory systems in fuzzy environment. These imprecise parameters defined on a bounded interval on the axis of real numbers and the physical characteristics of stocked items dictate the nature of inventory policies implemented to manage and control in the production system.   Methods: The modified fuzzy EOQ (FEOQ model is introduced, it assumes that a percentage of the on-hand inventory is wasted due to deterioration and considered as an enhancement to EOQ model to determine the optimal replenishment quantity so that the net profit is maximized. In theoretical analysis, the necessary and sufficient conditions of the existence and uniqueness of the optimal solutions are proved and further the concavity of the fuzzy net profit function is established. Computational algorithm using the software LINGO 13.0 version is developed to find the optimal solution.   Results and conclusions: The results of the numerical analysis enable decision-makers to quantify the effect of units lost due to deterioration on optimizing the fuzzy net profit for the retailer. Finally, sensitivity analyses of the optimal solution with respect the major parameters are also carried out. Furthermore fuzzy decision making is shown to be superior then crisp decision making in terms of profit maximization. 

  7. Lost in translation: Cultural divides in communication skills teaching identified in the ICCH 2016 student symposium.

    Science.gov (United States)

    Schopper, Heather K; Mohamed, Nasteha A; Seegel, Max; Gorina, Kseniya; Silverman, Jonathan; Rosenbaum, Marcy

    2017-11-01

    To provide a platform for learners' voices at an international conference on communication in healthcare. A group of medical students were invited to explore their experiences with communication skills learning at a symposium at the 2016 International Conference on Communication in Healthcare in Heidelberg, DE. Students from the US, Denmark, Germany, and Russia discussed their experiences with communication skills curriculum at their institutions. We identified divides that have challenged our ability to develop and maintain strong communication skills: 1) valuation of communication skills vs. other topics, 2) curricular theory vs. practice, 3) evaluation vs. feedback, 4) preclinical vs. clinical learning, and 5) the medical student vs. practicing clinician role. The points of transition we identified on the road of communication skills teaching highlight opportunities to strengthen the educational experience for students. Without an effort to address these divides, however, our communication skills may be lost in translation. Students value communication skills teaching during their medical education and there are opportunities to translate this to countries that currently lack robust curricula and to the real-life post-graduate setting. Support is necessary from students, teachers, and administrators, and focus on translation of skills during role transitions is needed. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. The Pribram, Lost City, Innisfree, and Neuschwanstein falls: An analysis of the atmospheric trajectories

    Science.gov (United States)

    Gritsevich, M. I.

    2008-10-01

    To date, several meteorites have been found for which their flight in the atmosphere was recorded by special fireball camera networks. Because of this, a thorough analysis of the instrumentally registered falls is of current importance. For such fireballs, not only the high-quality photo images of the motion in the atmosphere exist, but also the density and the shape of the meteor body fragments reached the Earth’s surface are known for sure. In the present study, for the Innisfree, Lost City, and Pribram fireballs, new models of the entry to the atmosphere have been built. The values of the ballistic coefficient and the mass-loss parameter providing the best approximation for the observations of the luminous trajectory segment with the analytical solution of the meteor physics equations have been obtained. From recent results of the numerical experiments on the supersonic airflow of bodies of various shapes, the preatmospheric masses of the fireballs, as well as the dynamic estimates of the mass at the other trajectory points, were obtained. In particular, the terminal mass of the fireballs in the lower segment of the analyzed trajectories is in good agreement with the total mass of the meteorite material recovered in all of the cases considered. Moreover, to calculate the acceleration of the meteor bodies, a new analytical formula has been suggested, which allows the obtained theoretical time dependencies of the velocity and altitude to be compared with the observational data.

  9. Years of life lost due to encounters with law enforcement in the USA, 2015-2016.

    Science.gov (United States)

    Bui, Anthony L; Coates, Matthew M; Matthay, Ellicott C

    2018-05-07

    To inform discussions on rates, burden and priority-setting in relation to police violence, we quantified the number and rate of years of life lost (YLLs) due to police violence by race/ethnicity and age in the USA, 2015-2016. We used data on the number of deaths due to police violence from 'The Counted', a media-based source compiled by The Guardian . YLLs are the difference between an individual's age at death and their corresponding standard life expectancy at age of death. There were 57 375 and 54 754 YLLs due to police violence in 2015 and 2016, respectively. People of colour comprised 38.5% of the population, but 51.5% of YLLs. YLLs were greatest among those aged 25-34 years, and the number of YLLs at younger ages was greater among people of colour than whites. The number of YLLs due to police violence is substantial. YLLs highlight that police violence disproportionately impacts young people, and the young people affected are disproportionately people of colour. Framing police violence as an important cause of deaths among young adults provides another valuable lens to motivate prevention efforts. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  10. Active dispersal in loggerhead sea turtles (Caretta caretta) during the 'lost years'.

    Science.gov (United States)

    Briscoe, D K; Parker, D M; Balazs, G H; Kurita, M; Saito, T; Okamoto, H; Rice, M; Polovina, J J; Crowder, L B

    2016-06-15

    Highly migratory marine species can travel long distances and across entire ocean basins to reach foraging and breeding grounds, yet gaps persist in our knowledge of oceanic dispersal and habitat use. This is especially true for sea turtles, whose complex life history and lengthy pelagic stage present unique conservation challenges. Few studies have explored how these young at-sea turtles navigate their environment, but advancements in satellite technology and numerical models have shown that active and passive movements are used in relation to open ocean features. Here, we provide the first study, to the best of our knowledge, to simultaneously combine a high-resolution physical forcing ocean circulation model with long-term multi-year tracking data of young, trans-oceanic North Pacific loggerhead sea turtles during their 'lost years' at sea. From 2010 to 2014, we compare simulated trajectories of passive transport with empirical data of 1-3 year old turtles released off Japan (29.7-37.5 straight carapace length cm). After several years, the at-sea distribution of simulated current-driven trajectories significantly differed from that of the observed turtle tracks. These results underscore current theories on active dispersal by young oceanic-stage sea turtles and give further weight to hypotheses of juvenile foraging strategies for this species. Such information can also provide critical geographical information for spatially explicit conservation approaches to this endangered population. © 2016 The Author(s).

  11. Lost-in-Space Star Identification Using Planar Triangle Principal Component Analysis Algorithm

    Directory of Open Access Journals (Sweden)

    Fuqiang Zhou

    2015-01-01

    Full Text Available It is a challenging task for a star sensor to implement star identification and determine the attitude of a spacecraft in the lost-in-space mode. Several algorithms based on triangle method are proposed for star identification in this mode. However, these methods hold great time consumption and large guide star catalog memory size. The star identification performance of these methods requires improvements. To address these problems, a star identification algorithm using planar triangle principal component analysis is presented here. A star pattern is generated based on the planar triangle created by stars within the field of view of a star sensor and the projection of the triangle. Since a projection can determine an index for a unique triangle in the catalog, the adoption of the k-vector range search technique makes this algorithm very fast. In addition, a sharing star validation method is constructed to verify the identification results. Simulation results show that the proposed algorithm is more robust than the planar triangle and P-vector algorithms under the same conditions.

  12. Replacing carbon lost from forests. An assessment of insurance, reserves, and expiring credits

    International Nuclear Information System (INIS)

    Subak, Susan

    2003-01-01

    Concern over the 'non-permanence' or reversibility of carbon sequestration projects has been prominent in discussions over how to develop guidelines for forest project investments under the Clean Development Mechanism (CDM) of the UNFCCC Kyoto Protocol. Accordingly, a number of approaches have been proposed that aim to help ensure that parties do not receive credit for carbon that is lost before project obligations are fulfilled. These approaches include forest carbon insurance, land reserves, and issuance of expiring credits. The potential costs of each of these different approaches are evaluated using a range of assumptions about project length, risk and discount rate, and a comparison of costs is ventured based on the estimated reduction in value of these credits compared with uninsured, and permanent credits. Obstacles to participation in the different approaches are discussed related to problems of long-term commitments, project scale, rising replacement costs, and low credit value. It is concluded that a system of expiring credits, which could be coupled with insurance or reserves, could guarantee obligations that span time-scales longer than that of conventional insurance policies while maintaining incentives for long-term sequestration

  13. From the Lost Radium Files: Misadventures in the Absence of Training, Regulation, and Accountability

    Energy Technology Data Exchange (ETDEWEB)

    Aronowitz, Jesse N., E-mail: jesse.aronowitz@umassmemorial.org [Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, Massachusetts (United States); Lubenau, Joel O. [Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, Massachusetts (United States)

    2012-11-15

    Purpose: Radium was the foundation of brachytherapy in the early decades of the 20th century. Despite being a most precious and perilous substance, it was mislaid with surprising frequency. This essay explores how it was lost, the efforts taken to recover it, and measures instituted to prevent mishandling. Methods and Materials: Review of contemporary literature, government publications, archives, and lay press. Results: Radium is a particularly dangerous substance because of its long half-life, its gaseous daughter (radon), and the high-energy emissions of its decay products. Despite the hazard, it was unregulated for most of the century. Any physician could obtain and administer it, and protocols for safe handling were generally lacking. Change came with appreciation of the danger, regulation, mandated training, and the institution of a culture of accountability. Unfortunately, careless management of medical radionuclides remains a global hazard. Conclusion: Responsible stewardship of radioactive material was not a high priority, for practitioners or the federal government, for much of the 20{sup th} century. As a result, large quantities of radium had gone astray, possibly subjecting the general public to continued radiation exposure. Lessons from the radium era remain relevant, as medical radionuclides are still mishandled.

  14. Redeeming Lost Mothers: Adolescent Antiretroviral Treatment and the Making of Home in South Africa.

    Science.gov (United States)

    Vale, Beth; Thabeng, Mildred

    2016-01-01

    In this article, we explore how adolescent antiretroviral treatment (ART) might be signified to repair sociality in Eastern Cape homes that have been ruptured by HIV/AIDS and maternal loss. The post-apartheid period has exposed these families to new forms of social fragmentation, propelled by the disintegration of wage labor, declining marriage rates, and a rampant HIV/AIDS epidemic. Drawing on eight months of ethnographic fieldwork (August 2013-April 2014), we show that in the homes of some adolescents born with HIV, these present-day domestic ruptures were discursively connected to the past shortcomings of their dead and absent mothers. In some familial narratives lost mothers were accused of disobeying their elders, neglecting their children, and flouting custom; their social transgressions were made manifest in their child's inherited HIV. By signifying adolescent ART-taking as an enactment of the discipline and care purportedly absent in their mothers, these families might also attempt to imbue ART, beyond its biomedical function, as a means of social repair.

  15. The family roles of siblings of people diagnosed with a mental disorder: heroes and lost children.

    Science.gov (United States)

    Sanders, Avihay; Szymanski, Kate; Fiori, Kate

    2014-08-01

    In order to cope with the diagnosis of mental illness in a family member, siblings may be forced to adjust their roles in the family. Taking into account the crucial role that some siblings play in caregiving for the mentally ill especially when the parents are no longer available, it is imperative to develop awareness of their unique needs and address them. Thirty-three adult siblings of people diagnosed with a mental disorder completed the Role Behaviour Inventory (RBI) and a general questionnaire including open-ended questions regarding the roles they played in their families of origin. Findings from the inventory and general questionnaire suggest that the well siblings score higher on two roles, the Hero and Lost Child, and lower on the Mascot and Scapegoat roles relative to a comparison group (N = 33). Being a sibling caregiver emerged as a risk factor to assume certain dysfunctional roles in the family. Implications for future research and therapy are discussed. © 2013 International Union of Psychological Science.

  16. ‘Excess of It’: Reviewing 'William Shakespeare’s Long Lost First Play (abridged'

    Directory of Open Access Journals (Sweden)

    Ronan James Hatfull

    2016-10-01

    Full Text Available It is timely in 2016, the 400th anniversary of Shakespeare’s death, to consider his legacy as a figure ingrained within popular culture. This critical review will investigate one of the chief exponents and parodists of the dichotomy which Shakespeare symbolises between supposed ‘highbrow’ and ‘lowbrow’ culture: the Reduced Shakespeare Company, a comedic theatre troupe who, to use their own slogan of droll self-deprecation, have been ‘reducing expectations since 1981’. The review will investigate the company’s most recent and tenth production, William Shakespeare’s Long Lost First Play (abridged, as a template for considering Shakespearean parody, focusing on the contemporary process of adapting and condensing Shakespeare’s texts within a populist context. Debuted at the Folger Shakespeare Library in April 2016, the play was first performed in the United Kingdom in August 2016 as part of the Edinburgh Festival Fringe. It is those performances upon which this review focuses. It will also use primary material drawn from live interviews and rehearsal observations conducted with Reed Martin and Austin Tichenor, the company’s managing partners, co-directors, co-writers and performers.

  17. The burden of ambient temperature on years of life lost in Guangzhou, China

    Science.gov (United States)

    Yang, Jun; Ou, Chun-Quan; Guo, Yuming; Li, Li; Guo, Cui; Chen, Ping-Yan; Lin, Hua-Liang; Liu, Qi-Yong

    2015-08-01

    Limited evidence is available on the association between temperature and years of life lost (YLL). We applied distributed lag non-linear model to assess the nonlinear and delayed effects of temperature on YLL due to cause-/age-/education-specific mortality in Guangzhou, China. We found that hot effects appeared immediately, while cold effects were more delayed and lasted for 14 days. On average, 1 °C decrease from 25th to 1st percentile of temperature was associated with an increase of 31.15 (95%CI: 20.57, 41.74), 12.86 (8.05, 17.68) and 6.64 (3.68, 9.61) YLL along lag 0-14 days for non-accidental, cardiovascular and respiratory diseases, respectively. The corresponding estimate of cumulative hot effects (1 °C increase from 75th to 99th percentile of temperature) was 12.71 (-2.80, 28.23), 4.81 (-2.25, 11.88) and 2.81 (-1.54, 7.16). Effect estimates of cold and hot temperatures-related YLL were higher in people aged up to 75 years and persons with low education level than the elderly and those with high education level, respectively. The mortality risks associated with cold and hot temperatures were greater on the elderly and persons with low education level. This study highlights that YLL provides a complementary method for assessing the death burden of temperature.

  18. Women's perspectives on public policy in India: a half-century of incomplete or lost agenda?

    Science.gov (United States)

    Krishnaraj, M

    2000-01-01

    52 years is not a small period for initiating progress. The promises enshrined in the Indian Constitution and the vision of women's full emancipation advanced during the nationalist struggle have alas not merely receded, but there is every danger that the lost momentum may not be made up unless once again the authors gear ourselves to intervene more forcefully in the polity and public policy. What we find despite tall pronouncements and a great deal of rhetoric and sentiment, is that the reality of public policy that emerges is full of ambiguities, ambivalences and contradictions, often taking away with the left hand what the right hand gives. Women's recommendations towards a radical movement for promoting gender equality in free India got jettisoned. The cost to women of this neglect is documented by plenty of data. In spheres such as employment, education, population, health, family laws, environment, and criminal justice, the response of the state has often been either detrimental to women or merely helped maintain the status quo. In many spheres, while women's interventions have been substantial, these were like a finger in the dyke, unable to reverse major policy directions.

  19. Lost or Fond? Effects of Nostalgia on Sad Mood Recovery Vary By Attachment Insecurity

    Directory of Open Access Journals (Sweden)

    Sarah Rose Cavanagh

    2015-06-01

    Full Text Available Nostalgia involves a fond recollection of people and events lost to time. Growing evidence indicates that nostalgia may ameliorate negative affective states such as loneliness and boredom. However, the effect of nostalgia on sadness is unknown, and there is little research on how social connectedness might impact nostalgia’s effects. Grounded in a theoretical framework whereby people with lower levels of attachment insecurity benefit more from nostalgia, we exposed participants to a mortality-related sad mood and then randomly assigned them to reflect on a nostalgic or an ordinary event memory. We examined changes in mood and electrodermal activity and found that nostalgic versus ordinary event memories led to a blunted recovery from sad mood, but that this effect was moderated by degree of attachment insecurity, such that participants with low insecurity benefited from nostalgia whereas people with high insecurity did not. These findings suggest that nostalgia’s benefits may be tied to the degree of confidence one has in one’s social relationships.

  20. Diagnosis Lost: Differences between Children who Had and who Currently Have an Autism Spectrum Disorder Diagnosis

    Science.gov (United States)

    Blumberg, Stephen J; Zablotsky, Benjamin; Avila, Rosa M; Colpe, Lisa J; Pringle, Beverly A; Kogan, Michael D

    2016-01-01

    Autism spectrum disorder (ASD) diagnoses sometimes change due to misdiagnosis, maturation, or treatment. This study uses a probability-based national survey—the Survey of Pathways to Diagnosis and Services—to compare currently diagnosed (n=1420) and previously diagnosed (n=187) children aged 6–17 years based on retrospective parental reports of early concerns about their children’s development, responses to those concerns by doctors and other health care providers, the type of provider who made the first ASD diagnosis, and the ASD subtype diagnoses received (if any). Propensity score matching was used to control for differences between the groups on children’s current level of functioning and other current characteristics that may have been related to diagnosis loss. Approximately 13% of the children ever diagnosed with ASD were estimated to have lost the diagnosis, and parents of 74% of them believe it was changed due to new information. Previously diagnosed children were less likely to have parents with early concerns about verbal skills, nonverbal communication, learning, and unusual gestures or movements. They were also less likely to have been referred to and diagnosed by a specialist. Previously diagnosed children were less likely to have ever received a diagnosis of Asperger’s disorder or autistic disorder. PMID:26489772

  1. Nanosecond Neutron Analysis for the search of the lost Leonardo's masterpiece, the Battle of Anghiari

    International Nuclear Information System (INIS)

    Kuznetsov, A.V.; Gorshkov, I.Yu.; Evsenin, A.V.; Osetrov, O.I.; Vakhtin, D.N.; Cosentino, A.; Seracini, M.

    2009-01-01

    Between 1505 and 1506 Leonardo Da Vinci painted his masterpiece, the Battle of Anghiari, in Palazzo Vecchio's Hall of 500 in Florence. The unfinished mural remained visible until 1563, when architect Giorgio Vasari undertook a renovation of the Hall and all traces of the Battle of Anghiari were lost. However, scholarly interpretation and scientific evidence suggest that the mural could be on the eastern wall, hidden behind a brick wall built in 1563 by Vasari. This paper discusses the possibility of using NNA/APT (Nanosecond Neutron Analysis/Associated Particle Technique) to establish the presence of the masterpiece by identifying behind the Vasari's wall chemical elements from the gesso preparation layer of the mural and possibly from its pigments. This paper reports on the experiments run with a simple NNA/APT system and the Monte Carlo simulations that have been carried out in order to outline the experimental setup of an advanced NNA/APT able to detect and locate the tiny amount of gesso and pigments.

  2. Presenteeism, Absenteeism, and Lost Work Productivity among Depressive Patients from Five Cities of Colombia.

    Science.gov (United States)

    Uribe, José Miguel; Pinto, Diana M; Vecino-Ortiz, Andres I; Gómez-Restrepo, Carlos; Rondón, Martín

    2017-12-01

    To estimate productivity losses due to absenteeism and presenteeism and their determinants in patients with depression from five Colombian cities. We used data from a multicenter, mixed-methods study of adult patients diagnosed with major depressive disorder or double depression (major depressive disorder plus dysthymia) during 2010. The World Health Organization's Health and Work Performance Questionnaire was used to assess absenteeism and presenteeism. We explored the determinants of productivity losses using a two-part model. We also used a costing model to calculate the corresponding monetary losses. We analyzed data from 107 patients employed in the last 4 weeks. Absenteeism was reported by 70% of patients; presenteeism was reported by all but one. Half of the patients reported a level of performance at work at least 50% below usual. Average number of hours per month lost to absenteeism and presenteeism was 43 and 51, respectively. The probability of any absenteeism was 17 percentage points lower in patients rating their mental health favorably compared with those rating it poorly (standard error [SE] 0.09; P productivity losses amounted to US $840 million. This study in a middle-income country confirms the high economic burden of depression. Health policies and workplace interventions ensuring adequate diagnosis and treatment of depression are recommended. Copyright © 2017. Published by Elsevier Inc.

  3. Aggression and guilt during mourning by parents who lost an infant.

    Science.gov (United States)

    Hasui, Chieko; Kitamura, Toshinori

    2004-01-01

    The authors conducted in-depth interviews with 38 mothers and fathers who had lost an infant. The focus of the interview was aggression and guilt during mourning work. The participants felt strong shame after separation. Phenomena such as strong irrational guilt, aggression, and hesitation toward others were similar to feelings typical of the paranoid-schizoid position. However, mourners did not lose their sense of reality, continued to do daily chores, and kept taking care of others. In this period, mourners were in disintegration, similar to individuals in the paranoid-schizoid position. Shame may be the feeling in the residue of the paranoid-schizoid position, through which they felt persecuted by others, their partner, relatives, and God. Their aggression was strong, but generally their aggression and impulses came to be used constructively and they progressed to integration. At the moment their children died, mourners fluctuated between disintegration and integration. After a certain interval, fluctuation subsided or integration predominated. In times of fluctuation, containers were very important for mourners to move toward integration. Participants reported changes in their lifestyle after the loss of a child. Mental health professionals should view aggressive impulses among such people during mourning not as an obstacle, but rather as a means to move toward integration. The authors speculate that a psychotherapist can serve as a container for mourners.

  4. Modeling lost production from destroyed platforms in the 2004-2005 Gulf of Mexico hurricane seasons

    International Nuclear Information System (INIS)

    Kaiser, Mark J.; Yu, Yunke; Jablonowski, Christopher J.

    2009-01-01

    Hurricanes Ivan, Katrina, and Rita passed through the Gulf of Mexico during 2004 and 2005 and resulted in the largest number of destroyed and damaged offshore oil and gas structures in the history of Gulf operations. In the final official government assessment, a total of 126 platforms were destroyed and over 183 structures were identified as having extensive damage. Production associated with wells and structures that are not redeveloped are classified as lost. The purpose of this paper is to derive functional relations that describe the likely contribution the collection of destroyed assets would have made to future production in the Gulf of Mexico. We estimate that the total remaining reserves from the set of destroyed structures range in value between 1.3 and 4.5 billion depending on the assumptions employed. We summarize the impact of the storms on the Gulf of Mexico oil and gas infrastructure and discuss the main issues involved in redevelopment decision making. A meta-model analytic framework is applied to perform sensitivity analysis and to explore the interactions of assumptions on model output. A discussion of the limitations of the analysis is presented. (author)

  5. The mourning process of older people with dementia who lost their spouse.

    Science.gov (United States)

    Watanabe, Akiko; Suwa, Sayuri

    2017-09-01

    To explore the mourning process of people with dementia who have lost their spouse, using family caregivers' and professionals' perspectives and to devise grief care for people with dementia. There have been studies on the loss of one's spouse; however, little is known about widows and widowers with dementia as they may find it hard to tell their perception and feelings to others accurately because of cognitive impairment. Qualitative descriptive study using semi-structured interviews. Seven family caregivers and six professional caregivers from day care centres were interviewed between June and September 2015. Qualitative content analysis was used to identify mourning behaviours of people with dementia. In the mourning process of people with dementia, different behaviours were found according to dementia stages and different circumstances. In FAST2, they could remember their spouse's death. In FAST4 -6, it took 1 year to be able to perceive their spouse's death and more time to store it. In FAST 7, people with dementia did not discern his spouse's death throughout the process. Furthermore, it was revealed that people with dementia followed a different mourning process from conventional ones. In the care of widows and widowers with dementia it is crucial to adjust circumstances to allow people with dementia to guess reality. Further studies are needed to clarify differences between the mourning process of people with dementia and that of intact older people to develop a grief model and educational programmes. © 2017 John Wiley & Sons Ltd.

  6. Excess alpha chains are lost from beta-thalassemic reticulocytes by proteolysis

    International Nuclear Information System (INIS)

    Testa, U.; Hinard, N.; Beuzard, Y.; Tsapis, A.; Galacteros, F.; Thomopoulos, P.; Rosa, J.

    1981-01-01

    During incubation of reticulocytes from patients with beta-thalassemia, after labeling of the hemoglobin with radioactive amino acids, the excess alpha chains are gradually lost from the cells. The aim of this study was to investigate the mechanism of this phenomenon. A system was developed in which reticulocytes from beta-thalassemia patients are labeled with [3H]leucine, washed several times in nonradioactive medium, and then incubated in the same medium containing puromycin added in order to stop further protein synthesis. The results have clearly shown that excess alpha chains are gradually degraded by proteolysis. N-ethylmaleimide or epsilon-aminocaproic acid inhibited the proteolysis of free alpha chains. The addition of either ATP or hemin did not change the rate of alpha chain degradation. The time required to degrade 50% of the pool of free alpha chains was directly dependent on the initial value of this pool. This finding suggests the absence of a significant individual variation in the ability to proteolyse free alpha chains

  7. Anomalously high variation in postnatal development is ancestral for dinosaurs but lost in birds

    Science.gov (United States)

    Griffin, Christopher T.; Nesbitt, Sterling J.

    2016-12-01

    Compared with all other living reptiles, birds grow extremely fast and possess unusually low levels of intraspecific variation during postnatal development. It is now clear that birds inherited their high rates of growth from their dinosaurian ancestors, but the origin of the avian condition of low variation during development is poorly constrained. The most well-understood growth trajectories of later Mesozoic theropods (e.g., Tyrannosaurus, Allosaurus) show similarly low variation to birds, contrasting with higher variation in extant crocodylians. Here, we show that deep within Dinosauria, among the earliest-diverging dinosaurs, anomalously high intraspecific variation is widespread but then is lost in more derived theropods. This style of development is ancestral for dinosaurs and their closest relatives, and, surprisingly, this level of variation is far higher than in living crocodylians. Among early dinosaurs, this variation is widespread across Pangaea in the Triassic and Early Jurassic, and among early-diverging theropods (ceratosaurs), this variation is maintained for 165 million years to the end of the Cretaceous. Because the Late Triassic environment across Pangaea was volatile and heterogeneous, this variation may have contributed to the rise of dinosaurian dominance through the end of the Triassic Period.

  8. Bone marrow support of the heart in pressure overload is lost with aging.

    Science.gov (United States)

    Sopko, Nikolai A; Turturice, Benjamin A; Becker, Mitchell E; Brown, Chase R; Dong, Feng; Popović, Zoran B; Penn, Marc S

    2010-12-21

    Exogenous stem cell delivery is under investigation to prevent and treat cardiac dysfunction. It is less studied as to the extent endogenous bone marrow derived stem cells contribute to cardiac homeostais in response to stress and the affects of aging on this stress response. To determine the role of bone marrow (BM) derived stem cells on cardiac homeostasis in response to pressure overload (PO) and how this response is altered by aging. Young (8 weeks) and old (>40 weeks) C57/b6 mice underwent homo- and heterochronic BM transplantation prior to transverse aortic constriction (TAC). We found that older BM is associated with decreased cardiac function following TAC. This decreased function is associated with decrease in BM cell engraftment, increased myocyte apoptosis, decreased myocyte hypertrophy, increased myocardial fibrosis and decreased cardiac function. Additionally, there is a decrease in activation of resident cells within the heart in response to PO in old mice. Interestingly, these effects are not due to alterations in vascular density or inflammation in response to PO or differences in ex vivo stem cell migration between young and old mice. BM derived stem cells are activated in response to cardiac PO, and the recruitment of BM derived cells are involved in cardiac myocyte hypertrophy and maintenance of function in response to PO which is lost with aging.

  9. "Lost milk?": Counting the economic value of breast milk in gross domestic product.

    Science.gov (United States)

    Smith, J P

    2013-11-01

    The contribution of breastfeeding and mothers milk to the economy is invisible in economic statistics. This article demonstrates how the economic value of human milk production can be included in economic statistics such as gross domestic product (GDP) and provides estimates for Australia, the United States, and Norway. The contribution of human milk and lactation to GDP in these countries is estimated using United Nations (System of National Accounting) guidelines and conventional economic valuation approaches to measuring production in GDP. In Australia, current human milk production levels exceed $3 billion annually. The United States has the potential to produce human milk worth more than US$110 billion a year, but currently nearly two thirds of this value is lost due to premature weaning. In Norway, production valued at US$907 million annually is 60% of its potential value. The potential loss of economic value from not protecting women's lactation and milk production from competing market pressures is large. Failure to account for mothers' milk production in GDP and other economic data has important consequences for public policy. The invisibility of human milk reduces the perceived importance of programs and regulations that protect and support women to breastfeed. The value of human milk can be measured using accepted international guidelines for calculating national income and production. It is quantitatively nontrivial and should be counted in GDP.

  10. Circadian melatonin concentration rhythm is lost in pregnant women with altered blood pressure rhythm.

    Science.gov (United States)

    Tranquilli, A L; Turi, A; Giannubilo, S R; Garbati, E

    2004-03-01

    We assessed the correlation between the rhythm of melatonin concentration and circadian blood pressure patterns in normal and hypertensive pregnancy. Ambulatory 24-h blood pressure and blood samples every 4 h were monitored in 16 primigravidae who had shown an abnormal circadian blood pressure pattern (eight pre-eclamptic and eight normotensive) in pregnancy and 6-12 months after pregnancy. The circadian rhythm was analyzed by chronobiological measures. Eight normotensive women with maintained blood pressure rhythm served as controls. During pregnancy, melatonin concentration was significantly higher in pre-eclamptic than in normotensive women (pre-eclampsia, 29.4 +/- 1.9 pg/ml, normotensin, altered rhythm, 15.6 +/- 2.1; controls, 22.7 +/- 1.8; p lost in all pregnant women with loss of blood pressure rhythm. After pregnancy, normotensive women showed a reappearance of both melatonin and blood pressure rhythm, whereas pre-eclamptic women showed a reappearance of blood pressure but not melatonin rhythm. The loss of blood pressure rhythm in pregnancy is consistent with the loss of melatonin concentration rhythm. In pre-eclamptic women, the normalization of blood pressure rhythm, while melatonin rhythm remained altered, suggests a temporal or causal priority of circadian concentration of melatonin in the determination of blood pressure trend.

  11. Mortality trends and years of potential life lost from gastric cancer in Mexico, 2000-2012

    Directory of Open Access Journals (Sweden)

    J.J. Sánchez-Barriga

    2016-04-01

    Conclusions: Using the world population age distribution as the standard, the age-adjusted mortality rate in Mexico per 100,000 inhabitants that died from GC decreased from 7.5 to 5.6 between 2000 and 2012. Chiapas and socioeconomic regions 1, 2, and 5 had the highest mortality from GC (Chiapas: 9.2, 95% CI 8.2-10.3 [2000] and 8.2, 95% CI 7.3-9 [2012], region 1: 5.5, 95% CI 5.2-5.9 [2000] and 5.3, 95% CI 4.9-5.7 [2012]; region 2: 5.3, 95% CI 5-5.6 [2000] and 5.4, 95% CI 5.1-5.8 [2012]; region 5: 6.1, 95% CI 5.6-6.6 [2000] and 4.6, 95% CI 4.2-5 [2012]. Chiapas and socioeconomic region 1 had the highest rate of years of potential life lost (Chiapas: 97.4 [2000] and 79.6 [2012] and region 1: 73.5 [2000] 65 [2012].

  12. The lost constellations a history of obsolete, extinct, or forgotten star lore

    CERN Document Server

    Barentine, John C

    2016-01-01

    Casual stargazers are familiar with many classical figures and asterisms composed of bright stars (e.g., Orion and the Plough), but this book reveals not just the constellations of today but those of yesteryear. The history of the human identification of constellations among the stars is explored through the stories of some influential celestial cartographers whose works determined whether new inventions survived. The history of how the modern set of 88 constellations was defined by the professional astronomy community is recounted, explaining how the constellations described in the book became permanently “extinct.”  Dr. Barentine addresses why some figures were tried and discarded, and also directs observers to how those figures can still be picked out on a clear night if one knows where to look. These lost constellations are described in great detail using historical references, ennabling observers to rediscover them on their own surveys of the sky. Treatment of the obsolete constellations as ...

  13. Lost in Translation: The Participatory Imperative and Local Water Governance in North Thailand and Southwest Germany

    Directory of Open Access Journals (Sweden)

    Andreas Neef

    2008-06-01

    Full Text Available Water management in Thailand and Germany has been marked by a command-and-control policy-style for decades, but has recently begun to move slowly towards more inclusive and participatory approaches. In Germany, the push for public participation stems from the recently promulgated European Union Water Framework Directive (EU WFD, while participatory and integrated river basin management in Thailand has been strongly promoted by major international donors. Drawing on case studies from two watersheds in North Thailand and Southwest Germany, this paper analyses how the participatory imperative in water governance is translated at the local level. Evidence suggests that in both countries public participation in water management is still in its infancy, with legislative and executive responsibilities being divided between a variety of state agencies and local authorities. Bureaucratic restructuring and technocratic attitudes, passive resistance on the part of administrative staff towards inclusive processes, and a trend towards the (recentralisation of responsibilities for water governance in both study regions undermines community-based and stakeholder-driven water governance institutions, thus calling into question the subsidiarity principle. State-driven participatory processes tend to remain episodic and ceremonial and have not (yet gone beyond the informative and consultative stage. Meaningful public participation, promised on paper and in speeches, gets lost in translation too often.

  14. 'Nine times the space' : from translator's notes to Milton's Paradise lost

    Directory of Open Access Journals (Sweden)

    Marjan Strojan

    1997-12-01

    Full Text Available Understanding the original meaning in the original context forms the basis of any translation. Translating poetry, however, requires an understanding which goes some way beyond the formal requirements of intelligent reading and informed interpretation. There are mental processes in any reading which are not easy to define in cognitive terms. Reading poetry, however, is by definition an aesthetic process, having a lot in common with our listening of music or looking at a work of art, where our cognitive functions are trained to be neither the exclusive interpreter of the subject nor the supreme selector of thought. Now, there are perhaps passages in Lacan or Nietzsche or Marx which can be enjoyed in synaesthetic terms as well as there are lines and sometimes whole paragraphs in Paradise Lost where little or no visual or musical perceptions are required beyond those usually· attached to any piece of theological meandering. But our perception of them is predetermined by the specific difference, inherent in the text, which relates not only to the difference of style, but also to the difference in our reading of them.

  15. Reconstructing a lost tradition: the philosophy of medical education in an age of reform.

    Science.gov (United States)

    Martin, Christopher

    2013-01-01

    At the 100th anniversary of Abraham Flexner's landmark report on medical education, critical reassessment of the direction of medical education reform evinced valuable interdisciplinary contributions from biomedicine, sociology, psychology and education theory. However, to date, philosophy has been absent from the discussion despite its long standing contribution to studies on education in other professions. This discussion paper examines how the philosophical tradition can contribute to scholarship in medical education. It begins with an explanation of the scholarly tradition of philosophy of education and its role in thinking in education more generally. It then makes links between this tradition and the context of medical education in the Flexner era of education reform. The paper then argues that this tradition is necessary to the understanding of medical education reform post-Flexner and that doctors must benefit from an education derived from this tradition in order to be able to carry out their work. These foundations are characterised as a hidden, but always present, tradition in medical education. Two ways in which this 'lost tradition' can inform medical education theory and practice are identified: firstly, by the establishment of a public canon of medical education texts that express such a tradition, and, secondly, by the incorporation of a variety of 'signature pedagogies' exemplary of liberal education. © Blackwell Publishing Ltd 2013.

  16. Diet Type and Changes in Food Cravings following Weight Loss: Findings from the POUNDS LOST Trial

    Science.gov (United States)

    Anton, Stephen D.; Gallagher, Jacqueline; Carey, Vincent J.; Laranjo, Nancy; Cheng, Jing; Champagne, Catherine M.; Ryan, Donna H.; McManus, Kathy; Loria, Catherine M.; Bray, George A.; Sacks, Frank M.; Williamson, Donald A.

    2014-01-01

    Few well-controlled trials have evaluated the effects that macronutrient composition has on changes in food cravings during weight loss treatment. The present study, which was part of the POUNDS LOST trial, investigated whether the fat and protein content of four different diets affected changes in specific food cravings in overweight and obese adults. A sample of 811 adults were recruited across two clinical sites, and each participant was randomly assigned to one of four macronutrient prescriptions: (1) Low fat (20% of energy), average protein (15% of energy); (2) Moderate fat (40%), average protein (15%); (3) Low fat (20%), high protein (25%); (4) Moderate fat (40%), high protein (25%). With few exceptions, the type of diet that participants were assigned did not differentially affect changes in specific food cravings. Participants assigned to the high fat diets, however, had reduced cravings for carbohydrates at Month12 (p< .05) and fruits and vegetables at Month 24. Also, participants assigned to high protein diets had increased cravings for sweets at Month 6 (p< .05). Participants in all four dietary conditions reported significant reductions in food cravings for specific types of foods (i.e., high fat foods, fast food fats, sweets, and carbohydrates/starches; all ps< .05). Cravings for fruits and vegetables, however, were increased at Month 24 (p< .05). Calorically restricted diets (regardless of their macronutrient composition) yielded significant reductions in cravings for fats, sweets, and starches whereas cravings for fruits and vegetables were increased. PMID:23010779

  17. Adherence is a multi-dimensional construct in the POUNDS LOST trial

    Science.gov (United States)

    Williamson, Donald A.; Anton, Stephen D.; Han, Hongmei; Champagne, Catherine M.; Allen, Ray; LeBlanc, Eric; Ryan, Donna H.; McManus, Katherine; Laranjo, Nancy; Carey, Vincent J.; Loria, Catherine M.; Bray, George A.; Sacks, Frank M.

    2011-01-01

    Research on the conceptualization of adherence to treatment has not addressed a key question: Is adherence best defined as being a uni-dimensional or multi-dimensional behavioral construct? The primary aim of this study was to test which of these conceptual models best described adherence to a weight management program. This ancillary study was conducted as a part of the POUNDS LOST trial that tested the efficacy of four dietary macro-nutrient compositions for promoting weight loss. A sample of 811 overweight/obese adults was recruited across two clinical sites, and each participant was randomly assigned to one of four macronutrient prescriptions: (1) Low fat (20% of energy), average protein (15% of energy); (2) High fat (40%), average protein (15%); (3) Low fat (20%), high protein (25%); (4) High fat (40%), high protein (25%). Throughout the first 6 months of the study, a computer tracking system collected data on eight indicators of adherence. Computer tracking data from the initial 6 months of the intervention were analyzed using exploratory and confirmatory analyses. Two factors (accounting for 66% of the variance) were identified and confirmed: (1) behavioral adherence and (2) dietary adherence. Behavioral adherence did not differ across the four interventions, but prescription of a high fat diet (vs. a low fat diet) was found to be associated with higher levels of dietary adherence. The findings of this study indicated that adherence to a weight management program was best conceptualized as being multi-dimensional, with two dimensions: behavioral and dietary adherence. PMID:19856202

  18. Has the Action for Failure to Act in the European Union Lost its Purpose?

    Directory of Open Access Journals (Sweden)

    Daukšienė Inga

    2014-12-01

    Full Text Available This article analyzes the purpose of the action for failure to act under article 265 of the Treaty on the Functioning of the European Union (TFEU. The statements are derived from the analysis of scientific literature, relevant legislation, practice of the European Union Court of Justice (CJEU and the European Union General Court (EUGC. Useful information has also been obtained from the opinions of general advocates of the CJEU. The article of TFEU 265, which governs the action for failure to act, is very abstract. For this reason, a whole procedure under the article 265 TFEU was developed by the EU courts. The original purpose of the action for failure to act was to constitute whether European Union (EU institution properly fulfilled its obligations under the EU legislation. However, in the course of case-law, a mere EU institution’s express refusal to fulfill its duties became sufficient to constitute that the EU institution acted and therefore action for failure to act became devoid of purpose. This article analyzes whether the action for failure to act has lost its purpose and become an ineffective legal remedy in the system of judicial review in the EU. Additionally, the action for failure to act is compared to similar national actions.

  19. Commentary: Lost in translation? How electronic health records structure communication, relationships, and meaning.

    Science.gov (United States)

    Lown, Beth A; Rodriguez, Dayron

    2012-04-01

    The media through which we communicate shape how we think, how we act, and who we are. Electronic health records (EHRs) may promote more effective, efficient, coordinated, safer care. Research is emerging, but more is needed to assess the effect of EHRs on communication, relationships, patients' trust, adherence, and health outcomes. The authors posit that EHRs introduce a "third party" into exam room interactions that competes with the patient for clinicians' attention, affects clinicians' capacity to be fully present, and alters the nature of communication, relationships, and physicians' sense of professional role. Screen-driven communication inhibits patients' narratives and diminishes clinicians' responses to patients' cues about psychosocial issues and emotional concerns. Students, trainees, and clinicians can, however, learn to integrate EHRs into triadic exam room interactions to facilitate information sharing and shared decision making.Student exposure to EHRs is currently limited. Educators and researchers should implement curricula and assessment tools to help learners integrate EHRs into clinical interactions in ways that foster, rather than diminish, communication and relationships. Further, educators must prioritize the teaching and modeling of self-awareness and self-calibration, mindful presence, and compassion within such curricula to prevent these important qualities and skills from being lost in translation in the digital era.

  20. Lost in transformation? Reviving ethics of care in hospital cultures of evidence-based healthcare.

    Science.gov (United States)

    Norlyk, Annelise; Haahr, Anita; Dreyer, Pia; Martinsen, Bente

    2017-07-01

    Drawing on previous empirical research, we provide an exemplary narrative to illustrate how patients have experienced hospital care organized according to evidence-based fast-track programmes. The aim of this paper was to analyse and discuss if and how it is possible to include patients' individual perspectives in an evidence-based practice as seen from the point of view of nursing theory. The paper highlights two conflicting courses of development. One is a course of standardization founded on evidence-based recommendations, which specify a set of rules that the patient must follow rigorously. The other is a course of democratization based on patients' involvement in care. Referring to the analysis of the narrative, we argue that, in the current implementation of evidence-based practice, the proposed involvement of patients resembles empty rhetoric. We argue that the principles and values from evidence-based medicine are being lost in the transformation into the current evidence-based hospital culture which potentially leads to a McDonaldization of nursing practice reflected as 'one best way'. We argue for reviving ethics of care perspectives in today's evidence practice as the fundamental values of nursing may potentially bridge conflicts between evidence-based practice and the ideals of patient participation thus preventing a practice of 'McNursing'. © 2017 John Wiley & Sons Ltd.

  1. The diversity and evolution of chelicerate hemocyanins

    Directory of Open Access Journals (Sweden)

    Rehm Peter

    2012-02-01

    Full Text Available Abstract Background Oxygen transport in the hemolymph of many arthropod species is facilitated by large copper-proteins referred to as hemocyanins. Arthropod hemocyanins are hexamers or oligomers of hexamers, which are characterized by a high O2 transport capacity and a high cooperativity, thereby enhancing O2 supply. Hemocyanin subunit sequences had been available from horseshoe crabs (Xiphosura and various spiders (Araneae, but not from any other chelicerate taxon. To trace the evolution of hemocyanins and the emergence of the large hemocyanin oligomers, hemocyanin cDNA sequences were obtained from representatives of selected chelicerate classes. Results Hemocyanin subunits from a sea spider, a scorpion, a whip scorpion and a whip spider were sequenced. Hemocyanin has been lost in Opiliones, Pseudoscorpiones, Solifugae and Acari, which may be explained by the evolution of trachea (i.e., taxon Apulmonata. Bayesian phylogenetic analysis was used to reconstruct the evolution of hemocyanin subunits and a relaxed molecular clock approach was applied to date the major events. While the sea spider has a simple hexameric hemocyanin, four distinct subunit types evolved before Xiphosura and Arachnida diverged around 470 Ma ago, suggesting the existence of a 4 × 6mer at that time. Subsequently, independent gene duplication events gave rise to the other distinct subunits in each of the 8 × 6mer hemocyanin of Xiphosura and the 4 × 6mer of Arachnida. The hemocyanin sequences were used to infer the evolutionary history of chelicerates. The phylogenetic trees support a basal position of Pycnogonida, a sister group relationship of Xiphosura and Arachnida, and a sister group relationship of the whip scorpions and the whip spiders. Conclusion Formation of a complex hemocyanin oligomer commenced early in the evolution of euchelicerates. A 4 × 6mer hemocyanin consisting of seven subunit types is conserved in most arachnids since more than 400 Ma, although some

  2. Science, evolution, and creationism

    National Research Council Canada - National Science Library

    Committee on Revising Science and Creationism

    ... are more comfortable. In the book Science, Evolution, and Creationism, a group of experts assembled by the National Academy of Sciences and the Institute of Medicine explain the fundamental methods of science, document...

  3. Co-Evolution.

    Science.gov (United States)

    McGhee, Robert

    2002-01-01

    Discusses the role of techniques of DNA analysis in assessing the genetic relationships between various species. Focuses on wolf-dog evolution using DNA evidence and historical data about human/wolf-dog relationships. (DDR)

  4. Evolution of dosimetric phantoms

    International Nuclear Information System (INIS)

    Reddy, A.R.

    2010-01-01

    In this oration evolution of the dosimetric phantoms for radiation protection and for medical use is briefly reviewed. Some details of the development of Indian Reference Phantom for internal dose estimation are also presented

  5. Evolution of microbial pathogens

    National Research Council Canada - National Science Library

    DiRita, Victor J; Seifert, H. Steven

    2006-01-01

    ... A. Hogan vvi ■ CONTENTS 8. Evolution of Pathogens in Soil Rachel Muir and Man-Wah Tan / 131 9. Experimental Models of Symbiotic Host-Microbial Relationships: Understanding the Underpinnings of ...

  6. Evolution, epigenetics and cooperation.

    Science.gov (United States)

    Bateson, Patrick

    2014-04-01

    Explanations for biological evolution in terms of changes in gene frequencies refer to outcomes rather than process. Integrating epigenetic studies with older evolutionary theories has drawn attention to the ways in which evolution occurs. Adaptation at the level of the gene is givingway to adaptation at the level of the organism and higher-order assemblages of organisms. These ideas impact on the theories of how cooperation might have evolved. Two of the theories, i.e. that cooperating individuals are genetically related or that they cooperate for self-interested reasons, have been accepted for a long time. The idea that adaptation takes place at the level of groups is much more controversial. However, bringing together studies of development with those of evolution is taking away much of the heat in the debate about the evolution of group behaviour.

  7. Chemical evolution and life

    Directory of Open Access Journals (Sweden)

    Malaterre Christophe

    2015-01-01

    Full Text Available In research on the origins of life, the concept of “chemical evolution” aims at explaining the transition from non-living matter to living matter. There is however strong disagreement when it comes to defining this concept more precisely, and in particular with reference to a chemical form of Darwinian evolution: for some, chemical evolution is nothing but Darwinian evolution applied to chemical systems before life appeared; yet, for others, it is the type of evolution that happened before natural selection took place, the latter being the birthmark of living systems. In this contribution, I review the arguments defended by each side and show how both views presuppose a dichotomous definition of “life”.

  8. Loss and gain of cone types in vertebrate ciliary photoreceptor evolution.

    Science.gov (United States)

    Musser, Jacob M; Arendt, Detlev

    2017-11-01

    Ciliary photoreceptors are a diverse cell type family that comprises the rods and cones of the retina and other related cell types such as pineal photoreceptors. Ciliary photoreceptor evolution has been dynamic during vertebrate evolution with numerous gains and losses of opsin and phototransduction genes, and changes in their expression. For example, early mammals lost all but two cone opsins, indicating loss of cone receptor types in response to nocturnal lifestyle. Our review focuses on the comparison of specifying transcription factors and cell type-specific transcriptome data in vertebrate retinae to build and test hypotheses on ciliary photoreceptor evolution. Regarding cones, recent data reveal that a combination of factors specific for long-wavelength sensitive opsin (Lws)- cones in non-mammalian vertebrates (Thrb and Rxrg) is found across all differentiating cone photoreceptors in mice. This suggests that mammalian ancestors lost all but one ancestral cone type, the Lws-cone. We test this hypothesis by a correlation analysis of cone transcriptomes in mouse and chick, and find that, indeed, transcriptomes of all mouse cones are most highly correlated to avian Lws-cones. These findings underscore the importance of specifying transcription factors in tracking cell type evolution, and shed new light on the mechanisms of cell type loss and gain in retina evolution. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Evolution of interstellar grains

    International Nuclear Information System (INIS)

    Greenberg, J.M.

    1984-01-01

    The principal aim of this chapter is to derive the properties of interstellar grains as a probe of local physical conditions and as a basis for predicting such properties as related to infrared emissivity and radiative transfer which can affect the evolution of dense clouds. The first sections will develop the criteria for grain models based directly on observations of gas and dust. A summary of the chemical evolution of grains and gas in diffuse and dense clouds follows. (author)

  10. Evolution of Things

    OpenAIRE

    Eiben, A. E.; Ferreira, N.; Schut, M.; Kernbach, S.

    2011-01-01

    Evolution is one of the major omnipresent powers in the universe that has been studied for about two centuries. Recent scientific and technical developments make it possible to make the transition from passively understanding to actively mastering evolution. As of today, the only area where human experimenters can design and manipulate evolutionary processes in full is that of Evolutionary Computing, where evolutionary processes are carried out in a digital space, inside computers, in simulat...

  11. Manipulation of quantum evolution

    Science.gov (United States)

    Cabera, David Jose Fernandez; Mielnik, Bogdan

    1994-01-01

    The free evolution of a non-relativistic charged particle is manipulated using time-dependent magnetic fields. It is shown that the application of a programmed sequence of magnetic pulses can invert the free evolution process, forcing an arbitrary wave packet to 'go back in time' to recover its past shape. The possibility of more general operations upon the Schrodinger wave packet is discussed.

  12. Chemical evolution of galaxies

    International Nuclear Information System (INIS)

    Matteucci, F.; Consiglio Nazionale delle Ricerche, Frascati

    1989-01-01

    In principle, a good model of galactic chemical evolution should fulfil the majority of well established observational constraints. The goal of this paper is to review the observational data together with the existing chemical evolution models for the Milky Way (the disk), Blue Compact and Elliptical galaxies and to show how well the models can account for the observations. Some open problems and future prospects are also discussed. (author)

  13. Developing theology for evolution

    Directory of Open Access Journals (Sweden)

    Chris Wiltsher

    2013-07-01

    Full Text Available This speculative paper explores one idea for approaching some of the problems which arise when the doctrines of Christian theology meet the current scientific understanding of evolution through natural selection. The main suggestion is that Christian theology should relax the requirement that God controls everything. Some implications of this move are explored, with a brief look at how similar ideas might be of use for non-Christian religions entering into dialogue with the theory of evolution

  14. Software evolution with XVCL

    DEFF Research Database (Denmark)

    Zhang, Weishan; Jarzabek, Stan; Zhang, Hongyu

    2004-01-01

    This chapter introduces software evolution with XVCL (XML-based Variant Configuration Language), which is an XML-based metaprogramming technique. As the software evolves, a large number of variants may arise, especially whtn such kinds of evolutions are related to multiple platforms as shown in our...... case study. Handling variants and tracing the impact of variants across the development lifecycle is a challenge. This chapter shows how we can maintain different versions of software in a reuse-based way....

  15. Evolution of massive stars

    International Nuclear Information System (INIS)

    Loore, C. de

    1984-01-01

    The evolution of stars with masses larger than 15 sun masses is reviewed. These stars have large convective cores and lose a substantial fraction of their matter by stellar wind. The treatment of convection and the parameterisation of the stellar wind mass loss are analysed within the context of existing disagreements between theory and observation. The evolution of massive close binaries and the origin of Wolf-Rayet Stars and X-ray binaries is also sketched. (author)

  16. Divergent Cumulative Cultural Evolution

    OpenAIRE

    Marriott, Chris; Chebib, Jobran

    2016-01-01

    Divergent cumulative cultural evolution occurs when the cultural evolutionary trajectory diverges from the biological evolutionary trajectory. We consider the conditions under which divergent cumulative cultural evolution can occur. We hypothesize that two conditions are necessary. First that genetic and cultural information are stored separately in the agent. Second cultural information must be transferred horizontally between agents of different generations. We implement a model with these ...

  17. Time evolution and use of multiple times in the N-body problem

    International Nuclear Information System (INIS)

    McGuire, J.H.; Godunov, A.L.

    2003-01-01

    Under certain conditions it is possible to describe time evolution using different times for different particles. Use of multiple times is optional in the independent particle approximation, where interparticle interactions are removed, and the N-particle evolution operator factors into N single-particle evolution operators. In this limit one may use either a single time, with a single energy-time Fourier transform, or N different times with a different energy-time transform for each particle. The use of different times for different particles is fully justified when coherence between single-particle amplitudes is lost, e.g., if relatively strong randomly fluctuating residual fields influence each particle independently. However, when spatial correlation is present the use of multiple times is not feasible, even when the evolution of the particles is uncorrelated in time. Some calculations in simple atomic systems with and without spatial and temporal correlation between different electrons are included

  18. Degeneration and domestication of a selfish gene in yeast: molecular evolution versus site-directed mutagenesis.

    Science.gov (United States)

    Koufopanou, Vassiliki; Burt, Austin

    2005-07-01

    VDE is a homing endonuclease gene in yeasts with an unusual evolutionary history including horizontal transmission, degeneration, and domestication into the mating-type switching locus HO. We investigate here the effects of these features on its molecular evolution. In addition, we correlate rates of evolution with results from site-directed mutagenesis studies. Functional elements have lower rates of evolution than degenerate ones and higher conservation at functionally important sites. However, functionally important and unimportant sites are equally likely to have been involved in the evolution of new function during the domestication of VDE into HO. The domestication event also indicates that VDE has been lost in some species and that VDE has been present in yeasts for more than 50 Myr.

  19. Olympijské hry jako kulturní událost The Olympic Games as a cultural event

    Directory of Open Access Journals (Sweden)

    Zvezdan Savić

    2007-02-01

    Full Text Available Olympijské hry se staly událostí zahrnující mnoho sportů, která zaměstnává nejen sportovce z různých zemí, ale také milióny diváků z celého světa. Z hlediska veřejného zájmu tedy převyšují jakoukoliv jinou sportovní nebo kulturní událost. Z iniciativy několika málo zemí a malého počtu sportovců se vyvinul historický fenomén dnešní civilizace, odehrávající se na určeném místě, s vlastními soutěžícími, nabídkou a pravidly. Olympijské hry vyjadřují ideologii různých národů na jediném místě, ideologii náboženství, zvyků, tradic, jazyků nebo obecně kultur. Probíhá při nich masová komunikace mezi soutěžícími a zbytkem celého světa. Sociální, vědecký, sportovně-technický a politický vývoj otevřel sportu jako sociálně-kulturnímu jevu široké obzory a sport se stal obecně prospěšným. Olympijských her se dnes účastní více než sto devadesát zemí. Sportovci a rozhodčí pocházejí z různých sociálních prostředí, což bylo v době, ve které hry vznikly, něco nepředstavitelného. Přesto je sociální komunikace mezi mladými lidmi celého světa v rámci této grandiózní události významným prvkem dnešních olympijských her. Můžeme při nich sledovat mistrovské sportovní výkony i setkávání mladých lidí bez ohledu na ideologii, rasu a náboženství. Právě to činí hry mimořádně krásnými a významnými. Autoři výzkumu se snažili podat podrobnější vysvětlení důležitých kulturních aspektů olympijských her a ukázat jejich sociální kontext. The Olympic Games have become a multi sport event, which entertains not only athletes from different countries, but a world wide audience numbering millions. They therefore exceed any other sports or cultural event when it comes to matters of public interest. Deriving from the initiative of a few countries and a small number of athletes, a historically significant phenomenon

  20. The ripples and waves of educational effectiveness research: some comments to ‘Getting lost in translation’

    NARCIS (Netherlands)

    Scheerens, Jaap

    2013-01-01

    The article ‘Getting lost in translation’ by Harris, Chapman, Muijs and Reynolds addresses the engagement of policy-makers and educational practitioners with (the results of) educational effectiveness and improvement research. In this commentary the article is discussed from the perspectives of

  1. Charles Darwin’s lost Cinereous Harrier found in the collection of the National Museum of Natural History Leiden

    NARCIS (Netherlands)

    Grouw, van H.; Steinheimer, F.D.

    2008-01-01

    During reorganisation of the Leiden bird collection a mounted harrier was found what seemed to be one of the still lost specimens collected by Darwin. After closer research it turned out it was indeed the last missing harrier of the Darwin collection.

  2. Lost in Space - Where the outer bound of localization space sets the lower bound on localization performance

    NARCIS (Netherlands)

    Dil, B.J.

    2013-01-01

    This research reflects my theoretical and experimental journey into the lost space of wireless radio localization in the far field of 2.4GHz Commercial-Off- The-Shelf (COTS) radios. At the end of this journey, we arrive at the conclu- sion that existing phase- and time-based localization systems

  3. A generation lost? Prolonged effects of labour market entry in times of high unemployment in the Netherlands

    NARCIS (Netherlands)

    Wolbers, M.H.J.

    2016-01-01

    After the economic crisis of the 1980s, concerns arose about whether the high youth unemployment at that time would produce a 'lost generation' of young people in the Netherlands. The same concerns have recently arisen about the potential effects of the current high rate of youth unemployment. The

  4. 50 CFR 23.52 - What are the requirements for replacing a lost, damaged, stolen, or accidentally destroyed CITES...

    Science.gov (United States)

    2010-10-01

    ... lost, damaged, stolen, or accidentally destroyed CITES document? 23.52 Section 23.52 Wildlife and...) CONVENTION ON INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application..., or accidentally destroyed CITES document? (a) Purpose. A Management Authority may issue a duplicate...

  5. 78 FR 15799 - 30-Day Notice of Proposed Information Collection: Statement Regarding a Lost or Stolen U.S...

    Science.gov (United States)

    2013-03-12

    ...: For a child under 16 ``This form must be mailed in'' and both parents or the child's legal guardians(s...-5806. Attention: Desk Officer for Department of State. FOR FURTHER INFORMATION CONTACT: Direct requests... before they receive a new passport, so that the lost or stolen passport can be invalidated (22 CFR parts...

  6. 41 CFR 102-34.135 - What do we do about a lost or stolen license plate?

    Science.gov (United States)

    2010-07-01

    ... 34-MOTOR VEHICLE MANAGEMENT Identifying and Registering Motor Vehicles License Plates § 102-34.135 What do we do about a lost or stolen license plate? You must report the loss or theft of license plates...), local police, to GSA Fleet when a GSA Fleet leased motor vehicle is involved, and to the Federal...

  7. 17 CFR 240.17f-1 - Requirements for reporting and inquiry with respect to missing, lost, counterfeit or stolen...

    Science.gov (United States)

    2010-04-01

    ... securities exchange who effects securities transactions through the trading facilities of the exchange and... can obtain a negotiable securities certificate; or (3) A reporting institution whose business... the securities certificate has been missing or lost for a period of two business days. Such report...

  8. Adaptive Evolution of Signaling Partners

    Science.gov (United States)

    Urano, Daisuke; Dong, Taoran; Bennetzen, Jeffrey L.; Jones, Alan M.

    2015-01-01

    Proteins that interact coevolve their structures. When mutation disrupts the interaction, compensation by the partner occurs to restore interaction otherwise counterselection occurs. We show in this study how a destabilizing mutation in one protein is compensated by a stabilizing mutation in its protein partner and their coevolving path. The pathway in this case and likely a general principle of coevolution is that the compensatory change must tolerate both the original and derived structures with equivalence in function and activity. Evolution of the structure of signaling elements in a network is constrained by specific protein pair interactions, by requisite conformational changes, and by catalytic activity. The heterotrimeric G protein-coupled signaling is a paragon of this protein interaction/function complexity and our deep understanding of this pathway in diverse organisms lends itself to evolutionary study. Regulators of G protein Signaling (RGS) proteins accelerate the intrinsic GTP hydrolysis rate of the Gα subunit of the heterotrimeric G protein complex. An important RGS-contact site is a hydroxyl-bearing residue on the switch I region of Gα subunits in animals and most plants, such as Arabidopsis. The exception is the grasses (e.g., rice, maize, sugarcane, millets); these plants have Gα subunits that replaced the critical hydroxyl-bearing threonine with a destabilizing asparagine shown to disrupt interaction between Arabidopsis RGS protein (AtRGS1) and the grass Gα subunit. With one known exception (Setaria italica), grasses do not encode RGS genes. One parsimonious deduction is that the RGS gene was lost in the ancestor to the grasses and then recently acquired horizontally in the lineage S. italica from a nongrass monocot. Like all investigated grasses, S. italica has the Gα subunit with the destabilizing asparagine residue in the protein interface but, unlike other known grass genomes, still encodes an expressed RGS gene, SiRGS1. SiRGS1

  9. The theory of evolution

    Directory of Open Access Journals (Sweden)

    Oleg Bazaluk

    2015-06-01

    Full Text Available The book The Theory of Evolution: from the Space Vacuum to Neural Ensembles and Moving Forward, an edition of 100 copies, was published in Russian language, in December 2014 in Kiev. Its Russian version is here: http://en.bazaluk.com/journals.html. Introduction, Chapter 10 and Conclusion published in English for the first time. Since 2004 author have been researching in the field of theory of Evolution, Big History. The book was written on the base of analysis of more than 2000 primary sources of this research topic. The volume is 90,000 words (with Reference. The book is for a wide range of professionals, from students to professors and researchers working in the fields of: philosophical anthropology, philosophy, Big History, cosmology, biology, neuroscience and etc. In the book, the author defines the evolution as continuous and nonlinear complication of the structure of matter, the types of interaction and environments; analyzes existing in modern science and philosophy approaches to the research of the process of evolution, degree of development of the factors and causes of evolution. Unifying interdisciplinary researches of evolution in cosmology, biology, neuroscience and philosophy, the author presents his vision of the model of «Evolving Matter», which allows us to consider not only the laws of transition of space vacuum in neural ensembles but also to see our Universe as a complication, heterogeneous organization. Interdisciplinary amount of information on the theory of evolution is systematized and a new method of world perception is proposed in the book.

  10. The Lost South Gobi Microcontinent: Protolith Studies of Metamorphic Tectonites and Implications for the Evolution of Continental Crust in Southeastern Mongolia

    Directory of Open Access Journals (Sweden)

    Matthew J. Heumann

    2013-08-01

    Full Text Available The Central Asian Orogenic Belt, or Altaids, is an amalgamation of volcanic arcs and microcontinent blocks that records a complex late Precambrian–Mesozoic accretionary history. Although microcontinents cored by Precambrian basement are proposed to play an integral role in the accretion process, a lack of isotopic data hampers volume estimates of newly produced arc-derived versus old-cratonic crust in southeastern Mongolia. This study investigates metamorphic tectonites in southern Mongolia that have been mapped as Precambrian in age, largely on the basis of their high metamorphic grade and high strain. Here we present results from microstructural analyses and U-Pb zircon geochronology on samples from Tavan Har (44.05° N, 109.55° E and the Yagan-Onch Hayrhan metamorphic core complex (41.89° N, 104.24° E. Our results show no compelling evidence for Precambrian basement in southeastern Mongolia. Rather, the protoliths to all tectonites examined are Paleozoic–Mesozoic age rocks, formed during Devonian–Carboniferous arc magmatism and subsequent Permian–Triassic orogenesis during collision of the South Mongolia arc with the northern margin of China. These results yield important insights into the Paleozoic accretionary history of southern Mongolia, including the genesis of metamorphic and igneous basement during the Paleozoic, as well as implications for subsequent intracontinental reactivation.

  11. Improvement in racial disparities in years of life lost in the USA since 1990.

    Science.gov (United States)

    Buchanich, Jeanine M; Doerfler, Shannon M; Lann, Michael F; Marsh, Gary M; Burke, Donald S

    2018-01-01

    To examine changes in cause-specific Years of Life Lost (YLL) by age, race, and sex group in the USA from 1990 to 2014. 60 million death reports from the National Center for Health Statistics (NCHS) were categorized by age group, sex, race, and cause of death. YLL were calculated using age-specific life expectancies. Age groups were: infants USA. In the year 1990 the YLL per 100,000 population was 21,103 for blacks, 14,160 for whites, and 7,417 for others. Between 1990 and 2014 overall YLL in the USA improved by 10%, but with marked variations in the rate of change across age, race, and sex groups. Blacks (all ages, both sexes) showed substantial improvement with a 28% reduction in YLL, compared to whites (all ages, both sexes) who showed a 4% reduction. Among blacks, improvements were seen in all age groups: reductions of 43%, 48%, 28%, and 25% among infants, children, adults, and older adults, respectively. Among whites, reductions of 33%, 44%, and 18% were seen in infants, children, and older adults, but there was a 6% increase in YLL among white adults. YLL increased by 18% in white adult females and declined 1% in white adult males. American Indian/Alaska Native women also had worsening in YLL, with an 8% increase. Asian Pacific Islanders consistently had the lowest YLL across all ages. Whites had a higher proportion of YLL due to overdose; blacks had a higher proportion due to homicide at younger ages and to heart disease at older ages. Race-based disparities in YLL in the USA since 1990 have narrowed considerably, largely as a result of improvements among blacks compared to whites. Adult white and American Indian / Alaskan Native females have experienced worsening YLL, while white males have experienced essentially no change. If recent trajectories continue, adult black/white disparities in YLL will continue to narrow.

  12. Being alone and expectations lost: a critical realist study of maternal depression in South Western Sydney.

    Science.gov (United States)

    Eastwood, John G; Kemp, Lynn A; Jalaludin, Bin B

    2015-01-01

    The study reported here is part of a critical realist multilevel study. It seeks to identify and explain complex perinatal contextual social and psychosocial mechanisms that may influence the developmental origins of health and disease, with a focus on the role of postnatal depression. The aims of the greater study are to: (1) describe the phenomenon of postnatal depression in South Western Sydney; and (2) identify mechanisms that would add to our understanding of the psycho-social causes of maternal depression. This paper will move beyond our previous quantitative descriptions of individual-level predictors of depressive symptoms by seeking the views of local mothers and practitioners, to explain the mechanisms that might be involved. The study was set in South Western Sydney, New South Wales, Australia. An Explanatory Theory Building Method was used. The previously reported quantitative study was a non-linear principal component analysis and logistic regression study of 15,389 months delivering in 2002 and 2003. This intensive qualitative study used open coding of interviews, of seven practitioners and three naturally occurring mothers groups, to enable maximum emergence. The theoretical concepts identified were: attachment and nurturing, infant temperament, unplanned pregnancy and sole parenthood, support for mothers, access to services, stress, financial hardship, isolation and marginalisation, mothers' "loss of control" and "power", and expectations and dreams. Being alone and expectations lost emerged as possible triggers of stress and depression for mothers. These findings might also apply to others who have their dreams shattered during life's transitions. In these situations social and cultural context can either nurture and support or marginalise and isolate. The challenge for policy and practice is to support mothers and their partners during the transition to parenthood within a challenging social and material context.

  13. Maritime Renaissance: oil begins to make up for lost seals and fish

    Energy Technology Data Exchange (ETDEWEB)

    Reid, W.

    2000-12-04

    The economic recovery of Newfoundland as a result of success in the Hibernia oilfield off the coast of Newfoundland is discussed. Oil production and the transport of oil from the Hibernia to the mainland by rugged double-hulled tankers that are about five times bigger than any other ship in Canada in terms of carrying capacity is a welcome event, considering that the seal hunt and the fishing industry that formerly provided sustenance to the people of Newfoundland have died as a result of world-wide pressure by animal rights groups, and indiscriminate overfishing. Transport of the crude oil from the Hibernia field is provided by Canship Ugland, a St. John's-based firm which now operates a fleet of three tankers. Each of the three vessels are capable of carrying 850,000 barrels of oil, or more than four times Hibernia's daily production. The 'Vinland' the latest of the three tankers to be commissioned, was built in South Korea, is 272 metres long and 46 metres wide. The ship is expected to carry oil from the rig 315 kms offshore to the Newfoundland Terminal at Whiffen Head, where the oil is picked up by smaller vessels. The 'Vinland' is equipped with the dynamic positioning feature which lets the ship maintain its maneuverability and position even if half her power is lost. The company employs people from all over the province and puts millions of dollars annually into the Newfoundland economy. 1 photo.

  14. Heat Source for Active Venting at the Lost City Hydrothermal Field

    Science.gov (United States)

    Smith, J. E.; Germanovich, L. N.; Lowell, R. P.

    2014-12-01

    Located at the inside corner high of the Mid-Atlantic Ridge (MAR), 30°N and the Atlantis Transform Fault (ATF), the Atlantis Massif has been uplifted over the past ~2 my. The Southern Ridge of this massif hosts the Lost City Hydrothermal Field (LCHF), an off-axis hydrothermal vent field with carbonate chimney ages surpassing 120,000 yrs. The fluids discharging at LCHF carry geochemical signals that show a direct interaction with serpentinites. However, mineralogical evidence suggests that peridotite hydration began early in the formation of oceanic core complexes and previous modeling results indicate that serpentinization is unlikely to generate the heat necessary to maintain current levels of discharge at LCHF. This work develops a model for the LCHF venting based on the evidence of tectonic strain, detachment faulting, serpentinization, and convective fluid flow. We constrain fluid flow at the LCHF by vent geochemistry, vent temperature, seismically inferred faulting, and expected geothermal gradient ≈100°C/km. Present understanding of tectonic processes at the intersection of MAR and ATF suggests that unroofing of the footwall and crustal flexing of the massif induced normal faults, which run parallel to the MAR, throughout the Southern Ridge. In the absence of the evidence of magmatism, we test the feasibility of the geothermal gradient to cause fluid circulation in the high-permeability, sub-vertical fault zone. Fluid circulation in the fault zone is complemented by the bulk porous flow driven through the Southern Ridge by the lateral temperature gradient between the cold water on the steep face along the ATF side and the hot interior of the massif. In this scenario, the high pH hydrothermal fluids pass through the serpentinized zone before discharging as both high-temperature focused flow (40°-91°C) and low-temperature (≈15°C) diffuse flow at the LCHF.

  15. Characterization of chromosomal regions conserved in Yersinia pseudotuberculosis and lost by Yersinia pestis.

    Science.gov (United States)

    Pouillot, Flavie; Fayolle, Corinne; Carniel, Elisabeth

    2008-10-01

    The transformation of the enteropathogenic bacterium Yersinia pseudotuberculosis into the plague bacillus, Yersinia pestis, has been accompanied by extensive genetic loss. This study focused on chromosomal regions conserved in Y. pseudotuberculosis and lost during its transformation into Y. pestis. An extensive PCR screening of 78 strains of the two species identified five regions (R1 to R5) and four open reading frames (ORFs; orf1 to orf4) that were conserved in Y. pseudotuberculosis and absent from Y. pestis. Their conservation in Y. pseudotuberculosis suggests a positive selective pressure and a role during the life cycle of this species. Attempts to delete two ORFs (orf3 and orf4) from the chromosome of strain IP32953 were unsuccessful, indicating that they are essential for its viability. The seven remaining loci were individually deleted from the IP32953 chromosome, and the ability of each mutant to grow in vitro and to kill mice upon intragastric infection was evaluated. Four loci (orf1, R2, R4, and R5) were not required for optimal growth or virulence of Y. pseudotuberculosis. In contrast, orf2, encoding a putative pseudouridylate synthase involved in RNA stability, was necessary for the optimal growth of IP32953 at 37 degrees C in a chemically defined medium (M63S). Deletion of R1, a region predicted to encode the methionine salvage pathway, altered the mutant pathogenicity, suggesting that the availability of free methionine is severely restricted in vivo. R3, a region composed mostly of genes of unknown functions, was necessary for both optimal growth of Y. pseudotuberculosis at 37 degrees C in M63S and for virulence. Therefore, despite their loss in Y. pestis, five of the nine Y. pseudotuberculosis-specific chromosomal loci studied play a role in the survival, growth, or virulence of this species.

  16. What are effective techniques for improving public confidence or restoring lost confidence in a regulator?

    International Nuclear Information System (INIS)

    Harbitz, O.; Isaksson, R.

    2006-01-01

    The conclusions and recommendations of this session can be summarized this way. The following list contains thoughts related to restoring lost confidence: - hard, long lasting event; - strategy: maximum transparency; - to listen, be open, give phone numbers etc. - ways to rebuild trust: frequent communication, being there, open and transparent; - don't be too defensive; if things could be done better, say it; - technical staff and public affair staff together from the beginning - answer all questions; - classifications, actions, instructions that differ much from the earlier ones must be well explained and motivated - and still cause a lot of problems; - things may turn out to be political; - communicative work in an early stage saves work later; - communication experts must be working shoulder to shoulder with other staff; On handling emergencies in general, some recipes proposed are: - better to over react than to under react; - do not avoid extreme actions: hit hard, hit fast; - base your decisions in strict principles; - first principle: public safety first; - when you are realizing plant A, you must have a plant B in your pocket: - be transparent - from the beginning; - crisis communication: early, frequent etc - people need to see political leaders, someone who is making decisions - technical experts are needed but are not enough. On how to involve stakeholders and the public in decision making, recommendations are: - new kind of thinking -. demanding for a organisation; - go to local level, meet local people, speak language people understand, you have to start from the very beginning - introducing yourself tell who you are and why you are there. (authors)

  17. Epilepsy, excess deaths and years of life lost from external causes.

    Science.gov (United States)

    Nevalainen, Olli; Simola, Mikko; Ansakorpi, Hanna; Raitanen, Jani; Artama, Miia; Isojärvi, Jouko; Auvinen, Anssi

    2016-05-01

    We systematically quantified excess mortality in epilepsy patients by cause of death using the population-attributable fraction and epilepsy-attributable years of potential life lost (YPLL) by age 75 years at ages 15 and over. We updated and undertook a re-review of mortality studies from our previous systematic review following PRISMA guidelines to identify cohort studies of general epilepsy populations reporting a relative risk (RR) of death by cause relative to the background rates in the population. Studies on epilepsy prevalence were identified through published reviews. Country-specific mortality figures were obtained from the WHO World Mortality Database. We performed a pooled analysis with the DerSimonian-Laird random effects method. In countries with very high Human Development Indices, epilepsy contributed to 0.5-1.1 % of all deaths in the total population. Among external causes, suicides (RR 2.9, 95 % confidence interval 2.2-3.8; I(2) 52 %) were the major contributor to YPLL, corresponding to 6.7 % and 4.2 % of excess YPLL due to epilepsy in the United States (US) and in the United Kingdom (UK) in 2010, with 541 (346-792) and 44 (28-65) excess suicide cases, respectively. Fatal accidental falls were more common, with 813 (610-1064) and 95 (71-125) excess deaths in the US and in the UK, but these caused only 2.0 % of excess YPLL as they occurred in older age groups. Suicides were the most important external cause of death in epilepsy patients in terms of excess YPLL, whereas other external causes were either more common in older ages or caused less excess deaths.

  18. Evolution: from cosmogenesis to biogenesis

    International Nuclear Information System (INIS)

    Lukacs, B.; Berczi, Sz.; Molnar, I.; Paal, G.

    1990-11-01

    The volume contains the material of an interdisciplinary evolution symposium. The purpose was to shed some light on possible connections between steps of evolution of matter on different levels of organisation. The topics involved are as follow: cosmogenesis; galactic and stellar evolution; formation and evolution of the solar system; global atmospheric and tectonic changes of Earth; viral evolution; phylogeny and evolution of terrestrial life; evolution of neural system; hominization. The material also includes some discussions of the underlying phenomena and laws of nature. (author)

  19. A High Performance System With Explicit Incorporation of ATC Regulations to Generate Contingency Plans for UAVs with Lost Communication, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose a comprehensive and systematic contingency plan generation framework to deal with lost communication in UAVs. ATC regulations are explicitly incorporated...

  20. Lossless Conditional Schema Evolution

    DEFF Research Database (Denmark)

    Jensen, Ole Guttorm; Bøhlen, Michael Hanspeter

    2003-01-01

    The paper considers conditional schema evolution, where schema changes change the schema of the tuples that satisfy the change condition. When the schema of a relation change some tuples may no longer fit the current schema. Handling the mismatch between the intended schema of tuples and the reco......The paper considers conditional schema evolution, where schema changes change the schema of the tuples that satisfy the change condition. When the schema of a relation change some tuples may no longer fit the current schema. Handling the mismatch between the intended schema of tuples...... and the recorded schema of tuples is at the core of a DBMS that supports schema evolution. We propose to keep track of schema mismatches at the level of individual tuples, and prove that conditionally evolving schemas, in contrast to current commercial database systems, are lossless when the schema evolves...

  1. Evolution of Scale Worms

    DEFF Research Database (Denmark)

    Gonzalez, Brett Christopher

    ) caves, and the interstitium, recovering six monophyletic clades within Aphroditiformia: Acoetidae, Aphroditidae, Eulepethidae, Iphionidae, Polynoidae, and Sigalionidae (inclusive of the former ‘Pisionidae’ and ‘Pholoidae’), respectively. Tracing of morphological character evolution showed a high degree...... of adaptability and convergent evolution between relatively closely related scale worms. While some morphological and behavioral modifications in cave polynoids reflected troglomorphism, other modifications like eye loss were found to stem from a common ancestor inhabiting the deep sea, further corroborating...... the deep sea ancestry of scale worm cave fauna. In conclusion, while morphological characterization across Aphroditiformia appears deceptively easy due to the presence of elytra, convergent evolution during multiple early radiations across wide ranging habitats have confounded our ability to reconstruct...

  2. Education and Evolution

    DEFF Research Database (Denmark)

    Hjermitslev, Hans Henrik

    2015-01-01

    Herbert Spencer’s ideas were first introduced to a Scandinavian audience in the early 1870s when the Danish philosopher Harald Høffding published and lectured on his evolutionary philosophy. At this time, Høffding also played an important role in disseminating Charles Darwin’s theory of evolution...... and in discussing the philosophical consequences of an evolutionary worldview. In the late 1870s and 1880s several of Spencer’s works were translated into Danish and Swedish and he became a household name among liberal intellectuals who primarily discussed his views on education and evolution. His most influential...... known foreign thinkers in the general public at the time of his death in 1903. Moreover, in the decades around 1900 Spencer’s thoughts on education were part of the curricula at many colleges of education. Spencer’s ideas on evolution and education were thus widely circulated and positively received...

  3. Quantum evolution across singularities

    International Nuclear Information System (INIS)

    Craps, Ben; Evnin, Oleg

    2008-01-01

    Attempts to consider evolution across space-time singularities often lead to quantum systems with time-dependent Hamiltonians developing an isolated singularity as a function of time. Examples include matrix theory in certain singular time-dependent backgounds and free quantum fields on the two-dimensional compactified Milne universe. Due to the presence of the singularities in the time dependence, the conventional quantum-mechanical evolution is not well-defined for such systems. We propose a natural way, mathematically analogous to renormalization in conventional quantum field theory, to construct unitary quantum evolution across the singularity. We carry out this procedure explicitly for free fields on the compactified Milne universe and compare our results with the matching conditions considered in earlier work (which were based on the covering Minkowski space)

  4. Boussinesq evolution equations

    DEFF Research Database (Denmark)

    Bredmose, Henrik; Schaffer, H.; Madsen, Per A.

    2004-01-01

    This paper deals with the possibility of using methods and ideas from time domain Boussinesq formulations in the corresponding frequency domain formulations. We term such frequency domain models "evolution equations". First, we demonstrate that the numerical efficiency of the deterministic...... Boussinesq evolution equations of Madsen and Sorensen [Madsen, P.A., Sorensen, O.R., 1993. Bound waves and triad interactions in shallow water. Ocean Eng. 20 359-388] can be improved by using Fast Fourier Transforms to evaluate the nonlinear terms. For a practical example of irregular waves propagating over...... a submerged bar, it is demonstrated that evolution equations utilising FFT can be solved around 100 times faster than the corresponding time domain model. Use of FFT provides an efficient bridge between the frequency domain and the time domain. We utilise this by adapting the surface roller model for wave...

  5. Software architecture evolution

    DEFF Research Database (Denmark)

    Barais, Olivier; Le Meur, Anne-Francoise; Duchien, Laurence

    2008-01-01

    Software architectures must frequently evolve to cope with changing requirements, and this evolution often implies integrating new concerns. Unfortunately, when the new concerns are crosscutting, existing architecture description languages provide little or no support for this kind of evolution....... The software architect must modify multiple elements of the architecture manually, which risks introducing inconsistencies. This chapter provides an overview, comparison and detailed treatment of the various state-of-the-art approaches to describing and evolving software architectures. Furthermore, we discuss...... one particular framework named Tran SAT, which addresses the above problems of software architecture evolution. Tran SAT provides a new element in the software architecture descriptions language, called an architectural aspect, for describing new concerns and their integration into an existing...

  6. Validering av Evolution 220

    OpenAIRE

    Krakeli, Tor-Arne

    2013-01-01

    - Det har blitt kjøpt inn et nytt spektrofotometer (Evolution 220, Thermo Scientific) til BioLab Nofima. I den forbindelsen har det blitt utført en validering som involverer kalibreringsstandarder fra produsenten og en test på normal distribusjon (t-test) på to metoder (Total fosfor, Tryptofan). Denne valideringen fant Evolution 220 til å være et akseptabelt alternativ til det allerede benyttede spektrofotometeret (Helios Beta). På bakgrunn av noen instrumentbegrensninger må de aktuelle an...

  7. TMDs: Evolution, modeling, precision

    Directory of Open Access Journals (Sweden)

    D’Alesio Umberto

    2015-01-01

    Full Text Available The factorization theorem for qT spectra in Drell-Yan processes, boson production and semi-inclusive deep inelastic scattering allows for the determination of the non-perturbative parts of transverse momentum dependent parton distribution functions. Here we discuss the fit of Drell-Yan and Z-production data using the transverse momentum dependent formalism and the resummation of the evolution kernel. We find a good theoretical stability of the results and a final χ2/points ≲ 1. We show how the fixing of the non-perturbative pieces of the evolution can be used to make predictions at present and future colliders.

  8. Emergence and Evolution

    DEFF Research Database (Denmark)

    Bullwinkle, Tammy J; Ibba, Michael

    2013-01-01

    ancestor and as such they provide insights into the evolution and development of the extant genetic code. Although the aaRSs have long been viewed as a highly conserved group of enzymes, findings within the last couple of decades have started to demonstrate how diverse and versatile these enzymes really...... are. Beyond their central role in translation, aaRSs and their numerous homologs have evolved a wide array of alternative functions both inside and outside translation. Current understanding of the emergence of the aaRSs, and their subsequent evolution into a functionally diverse enzyme family...

  9. Evolution 2.0

    DEFF Research Database (Denmark)

    Andersen, Casper; Bek-Thomsen, Jakob; Clasen, Mathias

    2013-01-01

    Studies in the history of science and education have documented that the reception and understanding of evolutionary theory is highly contingent on local factors such as school systems, cultural traditions, religious beliefs, and language. This has important implications for teaching evolution...... audiences readily available. As more and more schools require teachers to use low cost or free web-based materials, in the research community we need to take seriously how to facilitate that demand in communication strategies on evolution. This article addresses this challenge by presenting the learning...

  10. Methylome evolution in plants.

    Science.gov (United States)

    Vidalis, Amaryllis; Živković, Daniel; Wardenaar, René; Roquis, David; Tellier, Aurélien; Johannes, Frank

    2016-12-20

    Despite major progress in dissecting the molecular pathways that control DNA methylation patterns in plants, little is known about the mechanisms that shape plant methylomes over evolutionary time. Drawing on recent intra- and interspecific epigenomic studies, we show that methylome evolution over long timescales is largely a byproduct of genomic changes. By contrast, methylome evolution over short timescales appears to be driven mainly by spontaneous epimutational events. We argue that novel methods based on analyses of the methylation site frequency spectrum (mSFS) of natural populations can provide deeper insights into the evolutionary forces that act at each timescale.

  11. Chemical evolution of galaxies

    International Nuclear Information System (INIS)

    Vigroux, Laurent

    1979-01-01

    This research thesis addresses theories on the chemical evolution of galaxies which aim at explaining abundances of different elements in galaxies, and more particularly aims at improving the model by modifying hypotheses. After a description of the simple model and of its uncertainties, the author shows how it is possible to understand the evolution of the main elements. Predictions obtained with this model are then compared with the present knowledge on galaxies by considering them according to an increasing complexity: Sun's neighbourhood, our galaxy, other spiral galaxies, elliptical galaxies, and finally galaxy clusters. A specific attention is given to irregular galaxies which are the simplest systems [fr

  12. Calculation of the store house worker dose in a lost wax foundry using MCNP-4C

    International Nuclear Information System (INIS)

    Alegria, N.; Legarda, F.; Herranz, M.; Idoeta, R.

    2005-01-01

    Lost wax casting is an industrial process which permits the transmutation into metal of models made in wax. The wax model is covered with a siliceous shell of the required thickness and once this shell is built the set is heated and wax melted. Liquid metal is then cast into the shell replacing the wax. When the metal is cool, the shell is broken away in order to recover the metallic piece. In this process zircon sands are used for the preparation of the siliceous shell. These sands have varying concentrations of natural radionuclides: 238 U, 232 Th and 235 U together with their progenics. The zircon sand is distributed in bags of 50 kg, and 30 bags are on a pallet, weighing 1,500 kg. The pallets with the bags have dimensions 80 cm x 120 cm x 80 cm, and constitute the radiation source in this case. The only pathway of exposure to workers in the store house is external radiation. In this case there is no dust because the bags are closed and covered by plastic, the store house has a good ventilation rate and so radon accumulation is not possible. The workers do not touch with their hands the bags and consequently skin contamination will not take place. In this study all situations of external irradiation to the workers have been considered; transportation of the pallets from vehicle to store house, lifting the pallets to the shelf, resting of the stock on the shelf, getting down the pallets, and carrying the pallets to production area. Using MCNP-4C exposure situations have been simulated, considering that the source has a homogeneous composition, the minimum stock in the store house is constituted by 7 pallets, and the several distances between pallets and workers when they are at work. The photons flux obtained by MCNP-4C is multiplied by the conversion factor of Flux to Kerma for air by conversion factor to Effective Dose by Kerma unit, and by the number of emitted photons. Those conversion factors are obtained of ICRP 74 table 1 and table 17 respectively. This is

  13. Calculation of the store house worker dose in a lost wax foundry using MCNP-4C.

    Science.gov (United States)

    Alegría, Natalia; Legarda, Fernando; Herranz, Margarita; Idoeta, Raquel

    2005-01-01

    Lost wax casting is an industrial process which permits the transmutation into metal of models made in wax. The wax model is covered with a silicaceous shell of the required thickness and once this shell is built the set is heated and wax melted. Liquid metal is then cast into the shell replacing the wax. When the metal is cool, the shell is broken away in order to recover the metallic piece. In this process zircon sands are used for the preparation of the silicaceous shell. These sands have varying concentrations of natural radionuclides: 238U, 232Th and 235U together with their progenics. The zircon sand is distributed in bags of 50 kg, and 30 bags are on a pallet, weighing 1,500 kg. The pallets with the bags have dimensions 80 cm x 120 cm x 80 cm, and constitute the radiation source in this case. The only pathway of exposure to workers in the store house is external radiation. In this case there is no dust because the bags are closed and covered by plastic, the store house has a good ventilation rate and so radon accumulation is not possible. The workers do not touch with their hands the bags and consequently skin contamination will not take place. In this study all situations of external irradiation to the workers have been considered; transportation of the pallets from vehicle to store house, lifting the pallets to the shelf, resting of the stock on the shelf, getting down the pallets, and carrying the pallets to production area. Using MCNP-4C exposure situations have been simulated, considering that the source has a homogeneous composition, the minimum stock in the store house is constituted by 7 pallets, and the several distances between pallets and workers when they are at work. The photons flux obtained by MCNP-4C is multiplied by the conversion factor of Flux to Kerma for air by conversion factor to Effective Dose by Kerma unit, and by the number of emitted photons. Those conversion factors are obtained of ICRP 74 table 1 and table 17 respectively. This

  14. Mortality and potential years of life lost attributable to alcohol consumption in Canada in 2005.

    Science.gov (United States)

    Shield, Kevin D; Taylor, Benjamin; Kehoe, Tara; Patra, Jayadeep; Rehm, Jürgen

    2012-01-31

    Alcohol is a substantial risk factor for mortality according to the recent 2010 World Health Assembly strategy to reduce the harmful use of alcohol which outlined the need to characterize and monitor this burden. Accordingly, using new methodology we estimated 1) the number of deaths caused and prevented by alcohol consumption, and 2) the potential years of life lost (PYLLs) attributable to alcohol consumption in Canada in 2005. Mortality attributable to alcohol consumption was estimated by calculating Alcohol-Attributable Fractions (AAFs) (defined as the proportion of mortality that would be eliminated if the exposure was eliminated) using data from various sources. Indicators for alcohol consumption were obtained from the Canadian Alcohol and Drug Use Monitoring Survey 2008 and corrected for adult per capita recorded and unrecorded alcohol consumption. Risk relations were taken from the Comparative Risk Assessment within the current Global Burden of Disease (GBD) study. Due to concerns about the reliability of information specifying causes of death for people aged 65 or older, our analysis was limited to individuals aged 0 to 64 years. Calculation of the 95% confidence intervals (CIs) for the AAFs was performed using Monte Carlo random sampling. Information on mortality was obtained from Statistics Canada. A sensitivity analysis was performed comparing the mortality results obtained using our study methods to results obtained using previous methodologies. In 2005, 3,970 (95% CI: 810 to 7,170) deaths (4,390 caused and 420 prevented) and 134,555 (95% CI: 36,690 to 236,376) PYLLs were attributable to alcohol consumption for individuals aged 0 to 64 years. These figures represent 7.7% (95% CI: 1.6% to 13.9%) of all deaths and 8.0% (95% CI: 2.2% to 14.1%) of all PYLLs for individuals aged 0 to 64 years. The sensitivity analysis showed that the number of deaths as measured by this new methodology is greater than that if mortality was estimated using previous

  15. Mortality and potential years of life lost attributable to alcohol consumption in Canada in 2005

    Directory of Open Access Journals (Sweden)

    Shield Kevin D

    2012-01-01

    Full Text Available Abstract Background Alcohol is a substantial risk factor for mortality according to the recent 2010 World Health Assembly strategy to reduce the harmful use of alcohol which outlined the need to characterize and monitor this burden. Accordingly, using new methodology we estimated 1 the number of deaths caused and prevented by alcohol consumption, and 2 the potential years of life lost (PYLLs attributable to alcohol consumption in Canada in 2005. Methods Mortality attributable to alcohol consumption was estimated by calculating Alcohol-Attributable Fractions (AAFs (defined as the proportion of mortality that would be eliminated if the exposure was eliminated using data from various sources. Indicators for alcohol consumption were obtained from the Canadian Alcohol and Drug Use Monitoring Survey 2008 and corrected for adult per capita recorded and unrecorded alcohol consumption. Risk relations were taken from the Comparative Risk Assessment within the current Global Burden of Disease (GBD study. Due to concerns about the reliability of information specifying causes of death for people aged 65 or older, our analysis was limited to individuals aged 0 to 64 years. Calculation of the 95% confidence intervals (CIs for the AAFs was performed using Monte Carlo random sampling. Information on mortality was obtained from Statistics Canada. A sensitivity analysis was performed comparing the mortality results obtained using our study methods to results obtained using previous methodologies. Results In 2005, 3,970 (95% CI: 810 to 7,170 deaths (4,390 caused and 420 prevented and 134,555 (95% CI: 36,690 to 236,376 PYLLs were attributable to alcohol consumption for individuals aged 0 to 64 years. These figures represent 7.7% (95% CI: 1.6% to 13.9% of all deaths and 8.0% (95% CI: 2.2% to 14.1% of all PYLLs for individuals aged 0 to 64 years. The sensitivity analysis showed that the number of deaths as measured by this new methodology is greater than that if

  16. Paradigm Lost: Ocean Acidification Will Overturn the Concept of Larval-Fish Biophysical Dispersal

    Directory of Open Access Journals (Sweden)

    Jeffrey M. Leis

    2018-02-01

    hedging and colonization of new locations will decrease. The biophysical dispersal paradigm will be lost in theory and in fact, which is predicted to result in lower recruitment and less bet hedging for demersal, perciform fishes. More research is required to determine if the larvae of other Orders will be effected in the same way, or if warm- and cold-water fish faunas will be similarly effected.

  17. The curious history of relativity how Einstein's theory of gravity was lost and found again

    CERN Document Server

    Eisenstaedt, Jean

    2006-01-01

    Black holes may obliterate most things that come near them, but they saved the theory of general relativity. Einstein's theory was quickly accepted as the true theory of gravity after its publication in 1915, but soon took a back seat in physics to quantum mechanics and languished for decades on the blackboards of mathematicians. Not until the existence of black holes by Stephen Hawking and Roger Penrose in the 1960s, after Einstein's death, was the theory revived. Almost one hundred years after general relativity replaced Newton's theory of gravitation, The Curious History of Relativity tells the story of both events surrounding general relativity and the techniques employed by Einstein and the relativists to construct, develop, and understand his almost impenetrable theory. Jean Eisenstaedt, one of the world's leading experts on the subject, also discusses the theory's place in the evolution of twentieth-century physics. He describes the main stages in the development of general relativity: its beginnings,...

  18. Kraepelin's 'lost biological psychiatry'? Autointoxication, organotherapy and surgery for dementia praecox.

    Science.gov (United States)

    Noll, Richard

    2007-09-01

    Kraepelin believed that a chronic metabolic autointoxication, perhaps arising from the sex glands, eventually caused chemical damage to the brain and led to the symptoms of dementia praecox. The evolution of Kraepelin's autointoxication theory of dementia praecox is traced through the 5th to 8th (1895 to 1913) editions of his textbook, Psychiatrie. The historical context of autointoxication theory in medicine is explored in depth to enable the understanding of Kraepelin's aetiological assumption and his application of a rational treatment based on it--organotherapy. A brief account of the North American reception of Kraepelin's concept of dementia praecox, its autotoxic basis, and the preferred American style of rational treatment--surgery--concludes the discussion.

  19. Application and Continued Development of Thin Faraday Collectors as a Lost Ion Diagnostic for Tokamak Fusion Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    F. Ed Cecil

    2011-06-30

    This report summarizes the accomplishment of sixteen years of work toward the development of thin foil Faraday collectors as a lost energetic ion diagnostic for high temperature magnetic confinement fusion plasmas. Following initial, proof of principle accelerator based studies, devices have been tested on TFTR, NSTX, ALCATOR, DIII-D, and JET (KA-1 and KA-2). The reference numbers refer to the attached list of publications. The JET diagnostic KA-2 continues in operation and hopefully will provide valuable diagnostic information during a possible d-t campaign on JET in the coming years. A thin Faraday foil spectrometer, by virtue of its radiation hardness, may likewise provide a solution to the very challenging problem of lost alpha particle measurements on ITER and other future burning plasma machines.

  20. The Relationships Between Lost Work Time and Duration of Absence Spells: Proposal for a Payroll Driven Measure of Absenteeism

    Science.gov (United States)

    Hill, James J.; Slade, Martin D.; Cantley, Linda; Vegso, Sally; Fiellin, Martha; Cullen, Mark R.

    2011-01-01

    Objective To propose a standard measure of absenteeism (the work lost rate [WLR]) be included in future research to facilitate understanding and allow for translation of findings between scientific disciplines. Methods Hourly payroll data derived from “punch clock” reports was used to compare various measures of absenteeism used in the literature and the application of the proposed metric (N = 4000 workers). Results Unpaid hours and full absent days were highly correlated with the WLR (r = 0.896 to 0.898). The highest percentage of unpaid hours (lost work time) is captured by absence spells of 1 and 2 days duration. Conclusion The proposed WLR metric captures: 1) The range and distribution of the individual WLRs, 2) the percentage of subjects with no unpaid hours, and 3) the population WLR and should be included whenever payroll data is used to measure absenteeism. PMID:18617841

  1. The relationships between lost work time and duration of absence spells: proposal for a payroll driven measure of absenteeism.

    Science.gov (United States)

    Hill, James J; Slade, Martin D; Cantley, Linda; Vegso, Sally; Fiellin, Martha; Cullen, Mark R

    2008-07-01

    To propose a standard measure of absenteeism (the work lost rate [WLR]) be included in future research to facilitate understanding and allow for translation of findings between scientific disciplines. Hourly payroll data derived from "punch clock" reports was used to compare various measures of absenteeism used in the literature and the application of the proposed metric (N = 4000 workers). Unpaid hours and full absent days were highly correlated with the WLR (r = 0.896 to 0.898). The highest percentage of unpaid hours (lost work time) is captured by absence spells of 1 and 2 days duration. The proposed WLR metric captures: 1) The range and distribution of the individual WLRs, 2) the percentage of subjects with no unpaid hours, and 3) the population WLR and should be included whenever payroll data is used to measure absenteeism.

  2. A thin foil Faraday collector as a lost alpha detector for high yield d-t tokamak fusion plasmas

    International Nuclear Information System (INIS)

    Cecil, F. Ed

    2011-01-01

    This report summarizes the accomplishment of sixteen years of work toward the development of thin foil Faraday collectors as a lost energetic ion diagnostic for high temperature magnetic confinement fusion plasmas. Following initial, proof of principle accelerator based studies, devices have been tested on TFTR, NSTX, ALCATOR, DIII-D, and JET (KA-1 and KA-2). The reference numbers refer to the attached list of publications. The JET diagnostic KA-2 continues in operation and hopefully will provide valuable diagnostic information during a possible d-t campaign on JET in the coming years. A thin Faraday foil spectrometer, by virtue of its radiation hardness, may likewise provide a solution to the very challenging problem of lost alpha particle measurements on ITER and other future burning plasma machines.

  3. Days-lost to training and competition in relation to workload in 263 elite show-jumping horses in four European countries

    NARCIS (Netherlands)

    Egenvall, A; Tranquille, C A; Lönnell, A C; Bitschnau, C; Oomen, A|info:eu-repo/dai/nl/314417311; Hernlund, E; Montavon, S; Franko, M A; Murray, R C; Weishaupt, M A; Weeren, van R; Roepstorff, L; van Weeren, René|info:eu-repo/dai/nl/074628550

    2013-01-01

    Orthopaedic, or other, injuries in sports medicine can be quantified using the 'days-lost to training' concept. Both the training regimen and the surface used in training and racing can affect the health of racehorses. Our aim was to associate 'days-lost to training' in elite-level show-jumpers to

  4. Evolution of housing

    NARCIS (Netherlands)

    Slob, C.; Mohammadi, S.; Geraedts, R.P.

    2012-01-01

    ‘Perfection means something is complete and stands still and what stands still doesn’t change or evolve and is automatically dead. Everything in the universe changes, evolution implies that the creation is not complete hence the possibility of evolving’ (Osho, 1985). Our society and economy are

  5. The Evolution of Empathy

    Science.gov (United States)

    Hackney, Harold

    1978-01-01

    Therapeutic empathy has been an often-used construct by counseling professionals. Through that usage, the term has evolved in meaning and significance from its original presentation by Carl Rogers. This article traces that evolution by identifying its users and contributors over the past 20 years. (Author)

  6. Evolution Perception with Metaphors

    Science.gov (United States)

    Yilmaz, Fatih

    2016-01-01

    The main objective of this research is to find out how the teacher candidates who graduated from the Faculty of Theology and study in pedagogical formation program perceive the theory of evolution. Having a descriptive characteristic, this research is conducted with 63 Faculty of Theology graduate teacher candidates of which 36 is women and 27 is…

  7. Evolution of Business Models

    DEFF Research Database (Denmark)

    Antero, Michelle C.; Hedman, Jonas; Henningsson, Stefan

    2013-01-01

    The ERP industry has undergone dramatic changes over the past decades due to changing market demands, thereby creating new challenges and opportunities, which have to be managed by ERP vendors. This paper inquires into the necessary evolution of business models in a technology-intensive industry (e...

  8. Evolution of subsidiary competences

    DEFF Research Database (Denmark)

    Geisler Asmussen, Christian; Pedersen, Torben; Dhanaraj, Charles

    of competitive advantage of nations, we hypothesize the contingencies under which heterogeneity in host environments influences subsidiary competence configuration. We test our model with data from more than 2,000 subsidiaries in seven Western European countries. Our results provide new insights on the evolution...

  9. Titan Polar Landscape Evolution

    Science.gov (United States)

    Moore, Jeffrey M.

    2016-01-01

    With the ongoing Cassini-era observations and studies of Titan it is clear that the intensity and distribution of surface processes (particularly fluvial erosion by methane and Aeolian transport) has changed through time. Currently however, alternate hypotheses substantially differ among specific scenarios with respect to the effects of atmospheric evolution, seasonal changes, and endogenic processes. We have studied the evolution of Titan's polar region through a combination of analysis of imaging, elevation data, and geomorphic mapping, spatially explicit simulations of landform evolution, and quantitative comparison of the simulated landscapes with corresponding Titan morphology. We have quantitatively evaluated alternate scenarios for the landform evolution of Titan's polar terrain. The investigations have been guided by recent geomorphic mapping and topographic characterization of the polar regions that are used to frame hypotheses of process interactions, which have been evaluated using simulation modeling. Topographic information about Titan's polar region is be based on SAR-Topography and altimetry archived on PDS, SAR-based stereo radar-grammetry, radar-sounding lake depth measurements, and superposition relationships between geomorphologic map units, which we will use to create a generalized topographic map.

  10. Kinship and Human Evolution

    DEFF Research Database (Denmark)

    Bergendorff, Steen

    This book offers a exiting new explanation of human evolution. Based on insight from Anthropology is shows that human became 'cultured' beings capable of symbolic thought by developing rasting kinship based between groups that could not other wise survive in the harah climate condition during...

  11. Software Architecture Evolution

    Science.gov (United States)

    Barnes, Jeffrey M.

    2013-01-01

    Many software systems eventually undergo changes to their basic architectural structure. Such changes may be prompted by new feature requests, new quality attribute requirements, changing technology, or other reasons. Whatever the causes, architecture evolution is commonplace in real-world software projects. Today's software architects, however,…

  12. Open-Ended Evolution

    DEFF Research Database (Denmark)

    Taylor, Tim; Bedau, Mark A.; Channon, Alastair

    2016-01-01

    This report describes the First Workshop on Open-Ended Evolution: Recent Progress and Future Milestones (OEE1), held during the ECAL 2015 conference at the University of York, U.K., in July 2015. We briefly summarise the content of the talks and discussions and the workshop, and provide links...

  13. The Evolution of Galaxies

    Czech Academy of Sciences Publication Activity Database

    Palouš, Jan

    2007-01-01

    Roč. 17, - (2007), s. 34-40 ISSN 1220-5168. [Heliospere and galaxy. Sinaia, 03.05.2007-05.05.2007] R&D Projects: GA MŠk(CZ) LC06014 Institutional research plan: CEZ:AV0Z10030501 Keywords : ISM structure * stars formation * evolution of galaxies Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  14. MDSplus evolution continues

    International Nuclear Information System (INIS)

    Manduchi, G.; Fredian, T.W.; Stillerman, J.A.

    2012-01-01

    Highlights: ► The paper describes the recent evolution of the MDSplus data system. ► It presents a Use Case to explain MDSplus expressions. ► It presents the features recently developed. ► It presents the features under development. - Abstract: The MDSplus data system has been in operation on several fusion machines since 1991 and it is currently in use at over 30 sites spread over 5 continents. A consequence is the extensive feedback provided by the MDSplus user community for bug fixes and improvements and therefore the evolution of MDSplus is keeping pace with the evolution in data acquisition and management techniques. In particular, the recent evolution of MDSplus has been driven by the change in the paradigm for data acquisition in long lasting plasma discharges, where a sustained data stream is transferred from the acquisition devices into the database. Several new features are currently available or are being implemented in MDSplus. The features already implemented include a comprehensive Object-Oriented interface to the system, the python support for data acquisition devices and the full integration in EPICS. Work is in progress for the integration of multiple protocols and security systems in remote data access, a new high level data view layer and a new version of the jScope tool for online visualization and the optimized visualization of very large signals.

  15. Common envelope evolution

    NARCIS (Netherlands)

    Taam, Ronald E.; Ricker, Paul M.

    2010-01-01

    The common envelope phase of binary star evolution plays a central role in many evolutionary pathways leading to the formation of compact objects in short period systems. Using three dimensional hydrodynamical computations, we review the major features of this evolutionary phase, focusing on the

  16. Methylome evolution in plants

    NARCIS (Netherlands)

    Vidalis, Amaryllis; Živković, Daniel; Wardenaar, René; Roquis, David; Tellier, Aurélien; Johannes, Frank

    2016-01-01

    Despite major progress in dissecting the molecular pathways that control DNA methylation patterns in plants, little is known about the mechanisms that shape plant methylomes over evolutionary time. Drawing on recent intra- and interspecific epigenomic studies, we show that methylome evolution over

  17. The Evolution of Darwinism.

    Science.gov (United States)

    Stebbins, G. Ledyard; Ayala, Francisco J.

    1985-01-01

    Recent developments in molecular biology and new interpretations of the fossil record are gradually altering and adding to Charles Darwin's theory, which has been the standard view of the process of evolution for 40 years. Several of these developments and interpretations are identified and discussed. (JN)

  18. Darwinism: Evolution or Revolution?

    Science.gov (United States)

    Holt, Niles R.

    1989-01-01

    Maintains that Darwin's theory of evolution was more than a science versus religion debate; rather it was a revolutionary concept that influenced numerous social and political ideologies and movements throughout western history. Traces the impact of Darwin's work historically, utilizing a holistic approach. (RW)

  19. Modeling shoreface profile evolution

    NARCIS (Netherlands)

    Stive, M.J.F.; De Vriend, H.J.

    1995-01-01

    Current knowledge of hydro-, sediment and morpho-dynamics in the shoreface environment is insufficient to undertake shoreface-profile evolution modelling on the basis of first physical principles. We propose a simple, panel-type model to map observed behaviour. The internal dynamics are determined

  20. Modelling shoreface profile evolution

    NARCIS (Netherlands)

    Stive, Marcel J.F.; de Vriend, Huib J.

    1995-01-01

    Current knowledge of hydro-, sediment and morpho-dynamics in the shoreface environment is insufficient to undertake shoreface-profile evolution modelling on the basis of first physical principles. We propose a simple, panel-type model to map observed behaviour. The internal dynamics are determined