Hindcasting of decadal‐timescale estuarine bathymetric change with a tidal‐timescale model

Science.gov (United States)

Ganju, Neil K.; Schoellhamer, David H.; Jaffe, Bruce E.

2009-01-01

Hindcasting decadal-timescale bathymetric change in estuaries is prone to error due to limited data for initial conditions, boundary forcing, and calibration; computational limitations further hinder efforts. We developed and calibrated a tidal-timescale model to bathymetric change in Suisun Bay, California, over the 1867–1887 period. A general, multiple-timescale calibration ensured robustness over all timescales; two input reduction methods, the morphological hydrograph and the morphological acceleration factor, were applied at the decadal timescale. The model was calibrated to net bathymetric change in the entire basin; average error for bathymetric change over individual depth ranges was 37%. On a model cell-by-cell basis, performance for spatial amplitude correlation was poor over the majority of the domain, though spatial phase correlation was better, with 61% of the domain correctly indicated as erosional or depositional. Poor agreement was likely caused by the specification of initial bed composition, which was unknown during the 1867–1887 period. Cross-sectional bathymetric change between channels and flats, driven primarily by wind wave resuspension, was modeled with higher skill than longitudinal change, which is driven in part by gravitational circulation. The accelerated response of depth may have prevented gravitational circulation from being represented properly. As performance criteria became more stringent in a spatial sense, the error of the model increased. While these methods are useful for estimating basin-scale sedimentation changes, they may not be suitable for predicting specific locations of erosion or deposition. They do, however, provide a foundation for realistic estuarine geomorphic modeling applications.

Secular bathymetric variations of the North Channel in the Changjiang (Yangtze) Estuary, China, 1880-2013: Causes and effects

Science.gov (United States)

Mei, Xuefei; Dai, Zhijun; Wei, Wen; Li, Weihua; Wang, Jie; Sheng, Hao

2018-02-01

As the interface between the fluvial upland system and the open coast, global estuaries are facing serious challenges owing to various anthropogenic activities, especially to the Changjiang Estuary. Since the establishment of the Three Gorges Dam (TGD), currently the world's largest hydraulic structure, and certain other local hydraulic engineering structures, the Changjiang Estuary has experienced severe bathymetric variations. It is urgent to analyze the estuarine morphological response to the basin-wide disturbance to enable a better management of estuarine environments. North Channel (NC), the largest anabranched estuary in the Changjiang Estuary, is the focus of this study. Based on the analysis of bathymetric data between 1880 and 2013 and related hydrological data, we developed the first study on the centennial bathymetric variations of the NC. It is found that the bathymetric changes of NC include two main modes, with the first mode representing 64% of the NC variability, which indicates observable deposition in the mouth bar and its outer side area (lower reach); the second mode representing 11% of the NC variability, which further demonstrates channel deepening along the inner side of the mouth bar (upper reach) during 1970-2013. Further, recent erosion observed along the inner side of the mouth bar is caused by riverine sediment decrease, especially in relation to TGD induced sediment trapping since 2003, while the deposition along the lower reach since 2003 can be explained by the landward sediment transport because of flood-tide force strengthen under the joint action of TGD induced seasonal flood discharge decrease and land reclamation induced lower reach narrowing. Generally, the upper and lower NC reach are respectively dominated by fluvial and tidal discharge, however, episodic extreme floods can completely alter the channel morphology by smoothing the entire channel. The results presented herein for the NC enrich our understanding of bathymetric

Subtidal Bathymetric Changes by Shoreline Armoring Removal and Restoration Projects

Science.gov (United States)

Wallace, J.

2016-12-01

The Salish Sea, a region with a diverse coastline, is altered by anthropogenic shoreline modifications such as seawalls. In recent years, local organizations have moved to restore these shorelines. Current research monitors the changes restoration projects have on the upper beach, lower beach, and intertidal, however little research exists to record possible negative effects on the subtidal. The purpose of this research is to utilize multibeam sonar bathymetric data to analyze possible changes to the seafloor structure of the subtidal in response to shoreline modification and to investigate potential ecosystem consequences of shoreline alteration. The subtidal is home to several species including eelgrass (Zostera marina). Eelgrass is an important species in Puget Sound as it provides many key ecosystem functions including providing habitat for a wide variety of organisms, affecting the physics of waves, and sediment transport in the subtidal. Thus bathymetric changes could impact eelgrass growth and reduce its ability to provide crucial ecosystem services. Three Washington state study sites of completed shoreline restoration projects were used to generate data from areas of varied topographic classification, Seahurst Park in Burien, the Snohomish County Nearshore Restoration Project in Everett, and Cornet Bay State Park on Whidbey Island. Multibeam sonar data was acquired using a Konsberg EM 2040 system and post-processed in Caris HIPS to generate a base surface of one-meter resolution. It was then imported into the ArcGIS software suite for the generation of spatial metrics. Measurements of change were calculated through a comparison of historical and generated data. Descriptive metrics generated included, total elevation change, percent area changed, and a transition matrix of positive and negative change. Additionally, pattern metrics such as, surface roughness, and Bathymetric Position Index (BPI), were calculated. The comparison of historical data to new data

Variability In Long-Wave Runup as a Function of Nearshore Bathymetric Features

Energy Technology Data Exchange (ETDEWEB)

Dunkin, Lauren McNeill [Texas A & M Univ., College Station, TX (United States)

2010-05-01

Beaches and barrier islands are vulnerable to extreme storm events, such as hurricanes, that can cause severe erosion and overwash to the system. Having dunes and a wide beach in front of coastal infrastructure can provide protection during a storm, but the influence that nearshore bathymetric features have in protecting the beach and barrier island system is not completely understood. The spatial variation in nearshore features, such as sand bars and beach cusps, can alter nearshore hydrodynamics, including wave setup and runup. The influence of bathymetric features on long-wave runup can be used in evaluating the vulnerability of coastal regions to erosion and dune overtopping, evaluating the changing morphology, and implementing plans to protect infrastructure. In this thesis, long-wave runup variation due to changing bathymetric features as determined with the numerical model XBeach is quantified (eXtreme Beach behavior model). Wave heights are analyzed to determine the energy through the surfzone. XBeach assumes that coastal erosion at the land-sea interface is dominated by bound long-wave processes. Several hydrodynamic conditions are used to force the numerical model. The XBeach simulation results suggest that bathymetric irregularity induces significant changes in the extreme long-wave runup at the beach and the energy indicator through the surfzone.

Detailed bathymetric surveys in the central Indian Basin

Digital Repository Service at National Institute of Oceanography (India)

Kodagali, V.N.; KameshRaju, K.A.; Ramprasad, T.; George, P.; Jaisankar, S.

Over 420,000 line kilometers of echo-sounding data was collected in the Central Indian Basin. This data was digitized, merged with navigation data and a detailed bathymetric map of the Basin was prepared. The Basin can be broadly classified...

Bathymetric Contour Maps of Lakes Surveyed in Iowa in 2005

Science.gov (United States)

Linhart, S.M.; Lund, K.D.

2008-01-01

The U.S. Geological Survey, in cooperation with the Iowa Department of Natural Resources, conducted bathymetric surveys on seven lakes in Iowa during 2005 (Arrowhead Pond, Central Park Lake, Lake Keomah, Manteno Park Pond, Lake Miami, Springbrook Lake, and Yellow Smoke Lake). The surveys were conducted to provide the Iowa Department of Natural Resources with information for the development of total maximum daily load limits, particularly for estimating sediment load and deposition rates. The bathymetric surveys provide a baseline for future work on sediment loads and deposition rates for these lakes. All of the lakes surveyed in 2005 are man-made lakes with fixed spillways. Bathymetric data were collected using boat-mounted, differential global positioning system, echo depth-sounding equipment, and computer software. Data were processed with commercial hydrographic software and exported into a geographic information system for mapping and calculating area and volume. Lake volume estimates ranged from 47,784,000 cubic feet (1,100 acre-feet) at Lake Miami to 2,595,000 cubic feet (60 acre-feet) at Manteno Park Pond. Surface area estimates ranged from 5,454,000 square feet (125 acres) at Lake Miami to 558,000 square feet (13 acres) at Springbrook Lake.

Bathymetric highs in the mid-slope region of the western continental margin of India - Structure and mode of origin

Digital Repository Service at National Institute of Oceanography (India)

Rao, D.G.; Paropkari, A.L.; Krishna, K.S.; Chaubey, A.K.; Ajay, K.K.; Kodagali, V.N.

Analysis of the multi- and single beam bathymetric, seismic, magnetic and free-air gravity (ship-borne and satellite derived) data from the western continental margin of India between 12 degrees 40 minutes N and 15 degrees N had revealed...

A new bathymetric survey of the Suwałki Landscape Park lakes

Directory of Open Access Journals (Sweden)

Borowiak Dariusz

2016-12-01

Full Text Available The results of the latest bathymetric survey of 21 lakes in the Suwałki Landscape Park (SLP are presented here. Measurements of the underwater lake topography were carried out in the years 2012–2013 using the hydroacoustic method (sonar Lawrence 480M. In the case of four lakes (Błędne, Pogorzałek, Purwin, Wodziłki this was the first time a bathymetric survey had been performed. Field material was used to prepare bathymetric maps, which were then used for calculating the basic size and shape parameters of the lake basins. The results of the studies are shown against the nearly 90 year history of bathymetric surveying of the SLP lakes. In the light of the current measurements, the total area of the SLP lakes is over 634 hm2 and its limnic ratio is 10%. Lake water resources in the park were estimated at 143 037.1 dam3. This value corresponds to a retention index of 2257 mm. In addition, studies have shown that the previous morphometric data are not very accurate. The relative differences in the lake surface areas ranged from –14.1 to 9.1%, and in the case of volume – from –32.2 to 35.3%. The greatest differences in the volume, expressed in absolute values, were found in the largest SLP lakes: Hańcza (1716.1 dam3, Szurpiły (1282.0 dam3, Jaczno (816.4 dam3, Perty (427.1 dam3, Jegłówek (391.2 dam3 and Kojle (286.2 dam3. The smallest disparities were observed with respect to the data obtained by the IRS (Inland Fisheries Institute in Olsztyn. The IMGW (Institute of Meteorology and Water Management bathymetric measurements were affected by some significant errors, and morphometric parameters determined on their basis are only approximate.

MICROVEGA (MICRO VESSEL FOR GEODETICS APPLICATION: A MARINE DRONE FOR THE ACQUISITION OF BATHYMETRIC DATA FOR GIS APPLICATIONS

Directory of Open Access Journals (Sweden)

F. Giordano

2015-04-01

Full Text Available Bathymetric data are fundamental to produce navigational chart and sea-floor 3D models. They can be collected using different techniques and sensors on board of a variety of platforms, such as satellite, aircraft, ship and drone. The MicroVEGA drone is an Open Prototype of Autonomous Unmanned Surface Vessel (AUSV conceived, designed and built to operate in the coastal areas (0-20 meters of depth, where a traditional boat is poorly manoeuvrable. It is equipped with a series of sensors to acquire the morpho-bathymetric high precision data. In this paper we presents the result of the first case study, a bathymetric survey carried out at Sorrento Marina Grande. This survey is a typical application case of this technology; the Open Prototype MicroVega has an interdisciplinary breath and it is going to be applied to various research fields. In future, it will expect to do new knowledge, new survey strategies and an industrial prototype in fiberglass.

Multibeam bathymetric, gravity and magnetic studies over 79 degrees E fracture zone, central Indian basin

Digital Repository Service at National Institute of Oceanography (India)

KameshRaju, K.A.; Ramprasad, T.; Kodagali, V.N.; Nair, R.R.

A regional scale bathymetric map has been constructed for the 79 degrees E fracture zone (FZ) in the Central Indian Basin between 10 degrees 15'S and 14 degrees 45'S lat. and 78 degrees 55'E and 79 degrees 20'E long. using the high...

The utility of bathymetric echo sounding data in modelling benthic impacts using NewDEPOMOD driven by an FVCOM model.

Science.gov (United States)

Rochford, Meghan; Black, Kenneth; Aleynik, Dmitry; Carpenter, Trevor

2017-04-01

The Scottish Environmental Protection Agency (SEPA) are currently implementing new regulations for consenting developments at new and pre-existing fish farms. Currently, a 15-day current record from multiple depths at one location near the site is required to run DEPOMOD, a depositional model used to determine the depositional footprint of waste material from fish farms, developed by Cromey et al. (2002). The present project involves modifying DEPOMOD to accept data from 3D hydrodynamic models to allow for a more accurate representation of the currents around the farms. Bathymetric data are key boundary conditions for accurate modelling of current velocity data. The aim of the project is to create a script that will use the outputs from FVCOM, a 3D hydrodynamic model developed by Chen et al. (2003), and input them into NewDEPOMOD (a new version of DEPOMOD with more accurately parameterised sediment transport processes) to determine the effect of a fish farm on the surrounding environment. This study compares current velocity data under two scenarios; the first, using interpolated bathymetric data, and the second using bathymetric data collected during a bathymetric echo sounding survey of the site. Theoretically, if the hydrodynamic model is of high enough resolution, the two scenarios should yield relatively similar results. However, the expected result is that the survey data will be of much higher resolution and therefore of better quality, producing more realistic velocity results. The improvement of bathymetric data will also improve sediment transport predictions in NewDEPOMOD. This work will determine the sensitivity of model predictions to bathymetric data accuracy at a range of sites with varying bathymetric complexity and thus give information on the potential costs and benefits of echo sounding survey data inputs. Chen, C., Liu, H. and Beardsley, R.C., 2003. An unstructured grid, finite-volume, three-dimensional, primitive equations ocean model

Modeling and Analysis of Integrated Bathymetric and Geodetic Data for Inventory Surveys of Mining Water Reservoirs

Science.gov (United States)

Ochałek, Agnieszka; Lipecki, Tomasz; Jaśkowski, Wojciech; Jabłoński, Mateusz

2018-03-01

The significant part of the hydrography is bathymetry, which is the empirical part of it. Bathymetry is the study of underwater depth of waterways and reservoirs, and graphic presentation of measured data in form of bathymetric maps, cross-sections and three-dimensional bottom models. The bathymetric measurements are based on using Global Positioning System and devices for hydrographic measurements - an echo sounder and a side sonar scanner. In this research authors focused on introducing the case of obtaining and processing the bathymetrical data, building numerical bottom models of two post-mining reclaimed water reservoirs: Dwudniaki Lake in Wierzchosławice and flooded quarry in Zabierzów. The report includes also analysing data from still operating mining water reservoirs located in Poland to depict how bathymetry can be used in mining industry. The significant issue is an integration of bathymetrical data and geodetic data from tachymetry, terrestrial laser scanning measurements.

Predicting species diversity of benthic communities within turbid nearshore using full-waveform bathymetric LiDAR and machine learners.

Directory of Open Access Journals (Sweden)

Antoine Collin

Full Text Available Epi-macrobenthic species richness, abundance and composition are linked with type, assemblage and structural complexity of seabed habitat within coastal ecosystems. However, the evaluation of these habitats is highly hindered by limitations related to both waterborne surveys (slow acquisition, shallow water and low reactivity and water clarity (turbid for most coastal areas. Substratum type/diversity and bathymetric features were elucidated using a supervised method applied to airborne bathymetric LiDAR waveforms over Saint-Siméon-Bonaventure's nearshore area (Gulf of Saint-Lawrence, Québec, Canada. High-resolution underwater photographs were taken at three hundred stations across an 8-km(2 study area. Seven models based upon state-of-the-art machine learning techniques such as Naïve Bayes, Regression Tree, Classification Tree, C 4.5, Random Forest, Support Vector Machine, and CN2 learners were tested for predicting eight epi-macrobenthic species diversity metrics as a function of the class number. The Random Forest outperformed other models with a three-discretized Simpson index applied to epi-macrobenthic communities, explaining 69% (Classification Accuracy of its variability by mean bathymetry, time range and skewness derived from the LiDAR waveform. Corroborating marine ecological theory, areas with low Simpson epi-macrobenthic diversity responded to low water depths, high skewness and time range, whereas higher Simpson diversity relied upon deeper bottoms (correlated with stronger hydrodynamics and low skewness and time range. The degree of species heterogeneity was therefore positively linked with the degree of the structural complexity of the benthic cover. This work underpins that fully exploited bathymetric LiDAR (not only bathymetrically derived by-products, coupled with proficient machine learner, is able to rapidly predict habitat characteristics at a spatial resolution relevant to epi-macrobenthos diversity, ranging from clear to

Modeling and Analysis of Integrated Bathymetric and Geodetic Data for Inventory Surveys of Mining Water Reservoirs

Directory of Open Access Journals (Sweden)

Ochałek Agnieszka

2018-01-01

Full Text Available The significant part of the hydrography is bathymetry, which is the empirical part of it. Bathymetry is the study of underwater depth of waterways and reservoirs, and graphic presentation of measured data in form of bathymetric maps, cross-sections and three-dimensional bottom models. The bathymetric measurements are based on using Global Positioning System and devices for hydrographic measurements – an echo sounder and a side sonar scanner. In this research authors focused on introducing the case of obtaining and processing the bathymetrical data, building numerical bottom models of two post-mining reclaimed water reservoirs: Dwudniaki Lake in Wierzchosławice and flooded quarry in Zabierzów. The report includes also analysing data from still operating mining water reservoirs located in Poland to depict how bathymetry can be used in mining industry. The significant issue is an integration of bathymetrical data and geodetic data from tachymetry, terrestrial laser scanning measurements.

Bathymetric maps and water-quality profiles of Table Rock and North Saluda Reservoirs, Greenville County, South Carolina

Science.gov (United States)

Clark, Jimmy M.; Journey, Celeste A.; Nagle, Doug D.; Lanier, Timothy H.

2014-01-01

Lakes and reservoirs are the water-supply source for many communities. As such, water-resource managers that oversee these water supplies require monitoring of the quantity and quality of the resource. Monitoring information can be used to assess the basic conditions within the reservoir and to establish a reliable estimate of storage capacity. In April and May 2013, a global navigation satellite system receiver and fathometer were used to collect bathymetric data, and an autonomous underwater vehicle was used to collect water-quality and bathymetric data at Table Rock Reservoir and North Saluda Reservoir in Greenville County, South Carolina. These bathymetric data were used to create a bathymetric contour map and stage-area and stage-volume relation tables for each reservoir. Additionally, statistical summaries of the water-quality data were used to provide a general description of water-quality conditions in the reservoirs.

Sensitivity and spin-up times of cohesive sediment transport models used to simulate bathymetric change: Chapter 31

Science.gov (United States)

Schoellhamer, D.H.; Ganju, N.K.; Mineart, P.R.; Lionberger, M.A.; Kusuda, T.; Yamanishi, H.; Spearman, J.; Gailani, J. Z.

2008-01-01

Bathymetric change in tidal environments is modulated by watershed sediment yield, hydrodynamic processes, benthic composition, and anthropogenic activities. These multiple forcings combine to complicate simple prediction of bathymetric change; therefore, numerical models are necessary to simulate sediment transport. Errors arise from these simulations, due to inaccurate initial conditions and model parameters. We investigated the response of bathymetric change to initial conditions and model parameters with a simplified zero-dimensional cohesive sediment transport model, a two-dimensional hydrodynamic/sediment transport model, and a tidally averaged box model. The zero-dimensional model consists of a well-mixed control volume subjected to a semidiurnal tide, with a cohesive sediment bed. Typical cohesive sediment parameters were utilized for both the bed and suspended sediment. The model was run until equilibrium in terms of bathymetric change was reached, where equilibrium is defined as less than the rate of sea level rise in San Francisco Bay (2.17 mm/year). Using this state as the initial condition, model parameters were perturbed 10% to favor deposition, and the model was resumed. Perturbed parameters included, but were not limited to, maximum tidal current, erosion rate constant, and critical shear stress for erosion. Bathymetric change was most sensitive to maximum tidal current, with a 10% perturbation resulting in an additional 1.4 m of deposition over 10 years. Re-establishing equilibrium in this model required 14 years. The next most sensitive parameter was the critical shear stress for erosion; when increased 10%, an additional 0.56 m of sediment was deposited and 13 years were required to re-establish equilibrium. The two-dimensional hydrodynamic/sediment transport model was calibrated to suspended-sediment concentration, and despite robust solution of hydrodynamic conditions it was unable to accurately hindcast bathymetric change. The tidally averaged

International Bathymetric Chart of the Arctic Ocean, Version 2.23

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The goal of this initiative is to develop a digital data base that contains all available bathymetric data north of 64 degrees North, for use by mapmakers,...

International Bathymetric Chart of the Arctic Ocean, Version 1.0

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The goal of this initiative is to develop a digital data base that contains all available bathymetric data north of 64 degrees North, for use by mapmakers,...

Procedural Documentation and Accuracy Assessment of Bathymetric Maps and Area/Capacity Tables for Small Reservoirs

Science.gov (United States)

Wilson, Gary L.; Richards, Joseph M.

2006-01-01

Because of the increasing use and importance of lakes for water supply to communities, a repeatable and reliable procedure to determine lake bathymetry and capacity is needed. A method to determine the accuracy of the procedure will help ensure proper collection and use of the data and resulting products. It is important to clearly define the intended products and desired accuracy before conducting the bathymetric survey to ensure proper data collection. A survey-grade echo sounder and differential global positioning system receivers were used to collect water-depth and position data in December 2003 at Sugar Creek Lake near Moberly, Missouri. Data were collected along planned transects, with an additional set of quality-assurance data collected for use in accuracy computations. All collected data were imported into a geographic information system database. A bathymetric surface model, contour map, and area/capacity tables were created from the geographic information system database. An accuracy assessment was completed on the collected data, bathymetric surface model, area/capacity table, and contour map products. Using established vertical accuracy standards, the accuracy of the collected data, bathymetric surface model, and contour map product was 0.67 foot, 0.91 foot, and 1.51 feet at the 95 percent confidence level. By comparing results from different transect intervals with the quality-assurance transect data, it was determined that a transect interval of 1 percent of the longitudinal length of Sugar Creek Lake produced nearly as good results as 0.5 percent transect interval for the bathymetric surface model, area/capacity table, and contour map products.

Joint Interpretation of Bathymetric and Gravity Anomaly Maps Using Cross and Dot-Products.

Science.gov (United States)

Jilinski, Pavel; Fontes, Sergio Luiz

2010-05-01

0.1 Summary We present the results of joint map interpretation technique based on cross and dot-products applied to bathymetric and gravity anomaly gradients maps. According to the theory (Gallardo, Meju, 2004) joint interpretation of different gradient characteristics help to localize and empathize patterns unseen on one image interpretation and gives information about the correlation of different spatial data. Values of angles between gradients and their cross and dot-product were used. This technique helps to map unseen relations between bathymetric and gravity anomaly maps if they are analyzed separately. According to the method applied for the southern segment of Eastern-Brazilian coast bathymetrical and gravity anomaly gradients indicates a strong source-effect relation between them. The details of the method and the obtained results are discussed. 0.2 Introduction We applied this method to investigate the correlation between bathymetric and gravity anomalies at the southern segment of the Eastern-Brazilian coast. Gridded satellite global marine gravity data and bathymetrical data were used. The studied area is located at the Eastern- Brazilian coast between the 20° W and 30° W meridians and 15° S and 25° S parallels. The volcanic events responsible for the uncommon width of the continental shelf at the Abrolhos bank also were responsible for the formation of the Abrolhos islands and seamounts including the major Vitoria-Trindade chain. According to the literature this volcanic structures are expected to have a corresponding gravity anomaly (McKenzie, 1976, Zembruscki, S.G. 1979). The main objective of this study is to develop and test joint image interpretation method to compare spatial data and analyze its relations. 0.3 Theory and Method 0.3.1 Data sources The bathymetrical satellite data were derived bathymetry 2-minute grid of the ETOPO2v2 obtained from NOAA's National Geophysical Data Center (http://www.ngdc.noaa.gov). The satellite marine gravity 1

Impact of bathymetric system advances on hydrography

Digital Repository Service at National Institute of Oceanography (India)

Ranade, G.

undergone unprecedented changes with the advancement in the motion sensor technology. By late 1970 gyro stabilized accelerometer based attitude monitoring systems, computing roll, pitch and heave sensing and came in to existence. Doppler sonar principle...). “Multibeam bathymetric sonar: Sea Beam and Hydrochart”, Mar. Geod., vol. 4, pp.77-93. 4. Urick, R. (1975), “Principles of Underwater Acoustics”, McGraw – Hill. 5. Christian de Moustier, C. (1987). “Online Sea Beam acoustic imaging, Proc. Oceans ‘87...

Bathymetric patterns in standing stock and diversity of deep-sea nematodes at the long-term ecological research observatory HAUSGARTEN (Fram Strait)

Science.gov (United States)

Grzelak, Katarzyna; Kotwicki, Lech; Hasemann, Christiane; Soltwedel, Thomas

2017-08-01

Bathymetric patterns in standing stocks and diversity are a major topic of investigation in deep-sea biology. From the literature, responses of metazoan meiofauna and nematodes to bathymetric gradients are well studied, with a general decrease in biomass and abundance with increasing water depth, while bathymetric diversity gradients often, although it is not a rule, show a unimodal pattern. Spatial distribution patterns of nematode communities along bathymetric gradients are coupled with surface-water processes and interacting physical and biological factors within the benthic system. We studied the nematode communities at the Long-Term Ecological Research (LTER) observatory HAUSGARTEN, located in the Fram Strait at the Marginal Ice Zone, with respect to their standing stocks as well as structural and functional diversity. We evaluated whether nematode density, biomass and diversity indices, such as H0, Hinf, EG(50), Θ- 1, are linked with environmental conditions along a bathymetric transect spanning from 1200 m to 5500 m water depth. Nematode abundance, biomass and diversity, as well as food availability from phytodetritus sedimentation (indicated by chloroplastic pigments in the sediments), were higher at the stations located at upper bathyal depths (1200-2000 m) and tended to decrease with increasing water depth. A faunal shift was found below 3500 m water depth, where genus composition and trophic structure changed significantly and structural diversity indices markedly decreased. A strong dominance of very few genera and its high turnover particularly at the abyssal stations (4000-5500 m) suggests that environmental conditions were rather unfavorable for most genera. Despite the high concentrations of sediment-bound chloroplastic pigments and elevated standing stocks found at the deepest station (5500 m), nematode genus diversity remained the lowest compared to all other stations. This study provides a further insight into the knowledge of deep-sea nematodes

Recent Advances in Bathymetric Surveying of Continental Shelf Regions Using Autonomous Vehicles

Science.gov (United States)

Holland, K. T.; Calantoni, J.; Slocum, D.

2016-02-01

Obtaining bathymetric observations within the continental shelf in areas closer to the shore is often time consuming and dangerous, especially when uncharted shoals and rocks present safety concerns to survey ships and launches. However, surveys in these regions are critically important to numerical simulation of oceanographic processes, as bathymetry serves as the bottom boundary condition in operational forecasting models. We will present recent progress in bathymetric surveying using both traditional vessels retrofitted for autonomous operations and relatively inexpensive, small team deployable, Autonomous Underwater Vehicles (AUV). Both systems include either high-resolution multibeam echo sounders or interferometric sidescan sonar sensors with integrated inertial navigation system capabilities consistent with present commercial-grade survey operations. The advantages and limitations of these two configurations employing both unmanned and autonomous strategies are compared using results from several recent survey operations. We will demonstrate how sensor data collected from unmanned platforms can augment or even replace traditional data collection technologies. Oceanographic observations (e.g., sound speed, temperature and currents) collected simultaneously with bathymetry using autonomous technologies provide additional opportunities for advanced data assimilation in numerical forecasts. Discussion focuses on our vision for unmanned and autonomous systems working in conjunction with manned or in-situ systems to optimally and simultaneously collect data in environmentally hostile or difficult to reach areas.

Bathymetric study of the Neotectonic Naini Lake in outer Kumaun Himalaya

Digital Repository Service at National Institute of Oceanography (India)

Hashimi, N.H.; Pathak, M.C; Jauhari, P.; Nair, R.R.; Sharma, A.K.; Bhakuni, D.S.; Bisht, M.K.S.; Valdiya, K.S.

The Naini Lake is a product of rotational movement on a NW-SE trending Nainital Fault, quite after the establishment of the drainage of a mature stream named Balia Nala. Detailed bathymetric study, permits division of this crescent-shaped lake...

Using a personal watercraft for monitoring bathymetric changes at storm scale

NARCIS (Netherlands)

Van Son, S.T.J.; Lindenbergh, R.C.; De Schipper, M.A.; De Vries, S.; Duijnmayer, K.

2009-01-01

Monitoring and understanding coastal processes is important for the Netherlands since the most densely populated areas are situated directly behind the coastal defense. Traditionally, bathymetric changes are monitored at annual intervals, although nowadays it is understood that most dramatic changes

CRED Fagatele Bay National Marine Sanctuary Bathymetric Position Index Habitat Zones 2004

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Bathymetric Position Index (BPI) Zones derived from derivatives of Simrad EM-3000 multibeam bathymetry (3 m resolution). BPI zones are surficial characteristics of...

CRED Fagatele Bay National Marine Sanctuary Bathymetric Position Index Habitat Structures 2004

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Bathymetric Position Index (BPI) Structures are derived from derivatives of Simrad EM-3000 multibeam bathymetry (1 m and 3 m resolution). BPI structures are...

Quantifying the impact of bathymetric changes on the hydrological regimes in a large floodplain lake: Poyang Lake

Science.gov (United States)

Yao, Jing; Zhang, Qi; Ye, Xuchun; Zhang, Dan; Bai, Peng

2018-06-01

The hydrological regime of a lake is largely dependent on its bathymetry. A dramatic water level reduction has occurred in Poyang Lake in recent years, coinciding with significant bed erosion. Few studies have focused on the influence of bathymetric changes on the hydrological regime in such a complex river-lake floodplain system. This study combined hydrological data and a physically based hydrodynamic model to quantify the influence of the bathymetric changes (1998-2010) on the water level spatiotemporal distribution in Poyang Lake, based on a dry year (2006), a wet year (2010) and an average year (2000-2010). The following conclusions can be drawn from the results of this study: (1) The bed erosion of the northern outlet channel averaged 3 m, resulting in a decrease in the water level by 1.2-2 m in the northern channels (the most significantly influenced areas) and approximately 0.3 m in the central lake areas during low-level periods. The water levels below 16 m and 14 m were significantly affected during the rising period and recession period, respectively. The water level reduction was enhanced due to lower water levels. (2) The water surface profiles adjusted, and the rising and recession rates of the water level increased by 0.5-3.1 cm/d at the lake outlet. The bathymetric influence extended across the entire lake due to the emptying effect, resulting in a change in the water level distribution. The average annual outflow increased by 6.8%. (3) The bathymetric changes contributed approximately 14.4% to the extreme low water level in autumn 2006 and enhanced the drought in the dry season. This study quantified the impact of the bathymetric changes on the lake water levels, thereby providing a better understanding of the potential effects of continued sand mining operations and providing scientific explanations for the considerable variations in the hydrological regimes of Poyang Lake. Moreover, this study attempts to provide a reference for the assessment of

Application of an Autonomous/Unmanned Survey Vessel (ASV/USV in Bathymetric Measurements

Directory of Open Access Journals (Sweden)

Specht Cezary

2017-09-01

Full Text Available The accuracy of bathymetric maps, especially in the coastal zone, is very important from the point of view of safety of navigation and transport. Due to the continuous change in shape of the seabed, these maps are fast becoming outdated for precise navigation. Therefore, it is necessary to perform periodical bathymetric measurements to keep them updated on a current basis. At present, none of the institutions in Poland (maritime offices, Hydrographic Office of the Polish Navy which are responsible for implementation of this type of measurements has at their disposal a hydrographic vessel capable of carrying out measurements for shallow waters (at depths below 1 m. This results in emergence of large areas for which no measurement data have been obtained and, consequently, the maps in the coastal zones are rather unreliable.

Effects of Per-Pixel Variability on Uncertainties in Bathymetric Retrievals from High-Resolution Satellite Images

Directory of Open Access Journals (Sweden)

Elizabeth J. Botha

2016-05-01

Full Text Available Increased sophistication of high spatial resolution multispectral satellite sensors provides enhanced bathymetric mapping capability. However, the enhancements are counter-acted by per-pixel variability in sunglint, atmospheric path length and directional effects. This case-study highlights retrieval errors from images acquired at non-optimal geometrical combinations. The effects of variations in the environmental noise on water surface reflectance and the accuracy of environmental variable retrievals were quantified. Two WorldView-2 satellite images were acquired, within one minute of each other, with Image 1 placed in a near-optimal sun-sensor geometric configuration and Image 2 placed close to the specular point of the Bidirectional Reflectance Distribution Function (BRDF. Image 2 had higher total environmental noise due to increased surface glint and higher atmospheric path-scattering. Generally, depths were under-estimated from Image 2, compared to Image 1. A partial improvement in retrieval error after glint correction of Image 2 resulted in an increase of the maximum depth to which accurate depth estimations were returned. This case-study indicates that critical analysis of individual images, accounting for the entire sun elevation and azimuth and satellite sensor pointing and geometry as well as anticipated wave height and direction, is required to ensure an image is fit for purpose for aquatic data analysis.

Bathymetric map and area/capacity table for Castle Lake, Washington

Science.gov (United States)

Mosbrucker, Adam R.; Spicer, Kurt R.

2017-11-14

The May 18, 1980, eruption of Mount St. Helens produced a 2.5-cubic-kilometer debris avalanche that dammed South Fork Castle Creek, causing Castle Lake to form behind a 20-meter-tall blockage. Risk of a catastrophic breach of the newly impounded lake led to outlet channel stabilization work, aggressive monitoring programs, mapping efforts, and blockage stability studies. Despite relatively large uncertainty, early mapping efforts adequately supported several lake breakout models, but have limited applicability to current lake monitoring and hazard assessment. Here, we present the results of a bathymetric survey conducted in August 2012 with the purpose of (1) verifying previous volume estimates, (2) computing an area/capacity table, and (3) producing a bathymetric map. Our survey found seasonal lake volume ranges between 21.0 and 22.6 million cubic meters with a fundamental vertical accuracy representing 0.88 million cubic meters. Lake surface area ranges between 1.13 and 1.16 square kilometers. Relationships developed by our results allow the computation of lake volume from near real-time lake elevation measurements or from remotely sensed imagery.

Bathymetric survey of the Cayuga Inlet flood-control channel and selected tributaries in Ithaca, New York, 2016

Science.gov (United States)

Wernly, John F.; Nystrom, Elizabeth A.; Coon, William F.

2017-09-08

From July 14 to July 20, 2016, the U.S. Geological Survey, in cooperation with the City of Ithaca, New York, and the New York State Department of State, surveyed the bathymetry of the Cayuga Inlet flood-control channel and the mouths of selected tributaries to Cayuga Inlet and Cayuga Lake in Ithaca, N.Y. The flood-control channel, built by the U.S. Army Corps of Engineers between 1965 and 1970, was designed to convey flood flows from the Cayuga Inlet watershed through the City of Ithaca and minimize possible flood damages. Since that time, the channel has infrequently been maintained by dredging, and sediment accumulation and resultant shoaling have greatly decreased the conveyance of the channel and its navigational capability.U.S. Geological Survey personnel collected bathymetric data by using an acoustic Doppler current profiler. The survey produced a dense dataset of water depths that were converted to bottom elevations. These elevations were then used to generate a geographic information system bathymetric surface. The bathymetric data and resultant bathymetric surface show the current condition of the channel and provide the information that governmental agencies charged with maintaining the Cayuga Inlet for flood-control and navigational purposes need to make informed decisions regarding future maintenance measures.

Bathymetric survey and digital elevation model of Little Holland Tract, Sacramento-San Joaquin Delta, California

Science.gov (United States)

Snyder, Alexander G.; Lacy, Jessica R.; Stevens, Andrew W.; Carlson, Emily M.

2016-06-10

The U.S. Geological Survey conducted a bathymetric survey in Little Holland Tract, a flooded agricultural tract, in the northern Sacramento-San Joaquin Delta (the “Delta”) during the summer of 2015. The new bathymetric data were combined with existing data to generate a digital elevation model (DEM) at 1-meter resolution. Little Holland Tract (LHT) was historically diked off for agricultural uses and has been tidally inundated since an accidental levee breach in 1983. Shallow tidal regions such as LHT have the potential to improve habitat quality in the Delta. The DEM of LHT was developed to support ongoing studies of habitat quality in the area and to provide a baseline for evaluating future geomorphic change. The new data comprise 138,407 linear meters of real-time-kinematic (RTK) Global Positioning System (GPS) elevation data, including both bathymetric data collected from personal watercraft and topographic elevations collected on foot at low tide. A benchmark (LHT15_b1) was established for geodetic control of the survey. Data quality was evaluated both by comparing results among surveying platforms, which showed systematic offsets of 1.6 centimeters (cm) or less, and by error propagation, which yielded a mean vertical uncertainty of 6.7 cm. Based on the DEM and time-series measurements of water depth, the mean tidal prism of LHT was determined to be 2,826,000 cubic meters. The bathymetric data and DEM are available at http://dx.doi.org/10.5066/F7RX9954. 

Metabolic costs imposed by hydrostatic pressure constrain bathymetric range in the lithodid crab Lithodes maja.

Science.gov (United States)

Brown, Alastair; Thatje, Sven; Morris, James P; Oliphant, Andrew; Morgan, Elizabeth A; Hauton, Chris; Jones, Daniel O B; Pond, David W

2017-11-01

The changing climate is shifting the distributions of marine species, yet the potential for shifts in depth distributions is virtually unexplored. Hydrostatic pressure is proposed to contribute to a physiological bottleneck constraining depth range extension in shallow-water taxa. However, bathymetric limitation by hydrostatic pressure remains undemonstrated, and the mechanism limiting hyperbaric tolerance remains hypothetical. Here, we assess the effects of hydrostatic pressure in the lithodid crab Lithodes maja (bathymetric range 4-790 m depth, approximately equivalent to 0.1 to 7.9 MPa hydrostatic pressure). Heart rate decreased with increasing hydrostatic pressure, and was significantly lower at ≥10.0 MPa than at 0.1 MPa. Oxygen consumption increased with increasing hydrostatic pressure to 12.5 MPa, before decreasing as hydrostatic pressure increased to 20.0 MPa; oxygen consumption was significantly higher at 7.5-17.5 MPa than at 0.1 MPa. Increases in expression of genes associated with neurotransmission, metabolism and stress were observed between 7.5 and 12.5 MPa. We suggest that hyperbaric tolerance in L maja may be oxygen-limited by hyperbaric effects on heart rate and metabolic rate, but that L maja 's bathymetric range is limited by metabolic costs imposed by the effects of high hydrostatic pressure. These results advocate including hydrostatic pressure in a complex model of environmental tolerance, where energy limitation constrains biogeographic range, and facilitate the incorporation of hydrostatic pressure into the broader metabolic framework for ecology and evolution. Such an approach is crucial for accurately projecting biogeographic responses to changing climate, and for understanding the ecology and evolution of life at depth. © 2017. Published by The Company of Biologists Ltd.

Submerged karst landforms observed by multibeam bathymetric survey in Nagura Bay, Ishigaki Island, southwestern Japan

Science.gov (United States)

Kan, Hironobu; Urata, Kensaku; Nagao, Masayuki; Hori, Nobuyuki; Fujita, Kazuhiko; Yokoyama, Yusuke; Nakashima, Yosuke; Ohashi, Tomoya; Goto, Kazuhisa; Suzuki, Atsushi

2015-01-01

Submerged tropical karst features were discovered in Nagura Bay on Ishigaki Island in the southern Ryukyu Islands, Japan. The coastal seafloor at depths shallower than ~ 130 m has been subjected to repeated and alternating subaerial erosion and sedimentation during periods of Quaternary sea-level lowstands. We conducted a broadband multibeam survey in the central area of Nagura Bay (1.85 × 2.7 km) and visualized the high-resolution bathymetric results over a depth range of 1.6-58.5 m. Various types of humid tropical karst landforms were found to coexist within the bay, including fluviokarst, doline karst, cockpit karst, polygonal karst, uvalas, and mega-dolines. Although these submerged karst landforms are covered by thick postglacial reef and reef sediments, their shapes and sizes are distinct from those associated with coral reef geomorphology. The submerged landscape of Nagura Bay likely formed during multiple glacial and interglacial periods. According to our bathymetric results and the aerial photographs of the coastal area, this submerged karst landscape appears to have developed throughout Nagura Bay (i.e., over an area of approximately 6 × 5 km) and represents the largest submerged karst in Japan.

Processing and evaluation of riverine waveforms acquired by an experimental bathymetric LiDAR

Science.gov (United States)

Kinzel, P. J.; Legleiter, C. J.; Nelson, J. M.

2010-12-01

Accurate mapping of fluvial environments with airborne bathymetric LiDAR is challenged not only by environmental characteristics but also the development and application of software routines to post-process the recorded laser waveforms. During a bathymetric LiDAR survey, the transmission of the green-wavelength laser pulses through the water column is influenced by a number of factors including turbidity, the presence of organic material, and the reflectivity of the streambed. For backscattered laser pulses returned from the river bottom and digitized by the LiDAR detector, post-processing software is needed to interpret and identify distinct inflections in the reflected waveform. Relevant features of this energy signal include the air-water interface, volume reflection from the water column itself, and, ideally, a strong return from the bottom. We discuss our efforts to acquire, analyze, and interpret riverine surveys using the USGS Experimental Advanced Airborne Research LiDAR (EAARL) in a variety of fluvial environments. Initial processing of data collected in the Trinity River, California, using the EAARL Airborne Lidar Processing Software (ALPS) highlighted the difficulty of retrieving a distinct bottom signal in deep pools. Examination of laser waveforms from these pools indicated that weak bottom reflections were often neglected by a trailing edge algorithm used by ALPS to process shallow riverine waveforms. For the Trinity waveforms, this algorithm had a tendency to identify earlier inflections as the bottom, resulting in a shallow bias. Similarly, an EAARL survey along the upper Colorado River, Colorado, also revealed the inadequacy of the trailing edge algorithm for detecting weak bottom reflections. We developed an alternative waveform processing routine by exporting digitized laser waveforms from ALPS, computing the local extrema, and fitting Gaussian curves to the convolved backscatter. Our field data indicate that these techniques improved the

Rip current evidence by hydrodynamic simulations, bathymetric surveys and UAV observation

Directory of Open Access Journals (Sweden)

G. Benassai

2017-09-01

Full Text Available The prediction of the formation, spacing and location of rip currents is a scientific challenge that can be achieved by means of different complementary methods. In this paper the analysis of numerical and experimental data, including RPAS (remotely piloted aircraft systems observations, allowed us to detect the presence of rip currents and rip channels at the mouth of Sele River, in the Gulf of Salerno, southern Italy. The dataset used to analyze these phenomena consisted of two different bathymetric surveys, a detailed sediment analysis and a set of high-resolution wave numerical simulations, completed with Google EarthTM images and RPAS observations. The grain size trend analysis and the numerical simulations allowed us to identify the rip current occurrence, forced by topographically constrained channels incised on the seabed, which were compared with observations.

Swath bathymetric investigation of the seamounts located in the Laxmi Basin, eastern Arabian Sea

Digital Repository Service at National Institute of Oceanography (India)

Bhattacharya, G.C.; Murty, G.P.S.; Srinivas, K.; Chaubey, A.K.; Sudhakar, T.; Nair, R.R.

Multibeam (hydrosweep) swath bathymetric investigations revealed the presence of a NNW trending linear seamount chain along the axial part of the Laxmi Basin in the eastern Arabian Sea, between 15~'N, 70~'15'E and 17~'20'N, 69~'E. This chain...

The estimation of sea floor dynamics from bathymetric surveys of a sand wave area

NARCIS (Netherlands)

Dorst, Leendert; Roos, Pieter C.; Hulscher, Suzanne J.M.H.; Lindenbergh, R.C.

2009-01-01

The analysis of series of offshore bathymetric surveys provides insight into the morphodynamics of the sea floor. This knowledge helps to improve resurvey policies for the maintenance of port approaches and nautical charting, and to validate morphodynamic models. We propose a method for such an

Magnetic and bathymetric investigations over the Vema Region of the Central Indian Ridge: Tectonic implications

Digital Repository Service at National Institute of Oceanography (India)

Drolia, R.K.; Ghose, I.; Subrahmanyam, A.S.; Rao, M.M.M.; Kessarkar, P.M.; Murthy, K.S.R.

Honeywell Elac narrowbeam echosounder. Post-cruise proces- sing involved digitisation of echograms, interpolation of data at 1 min intervals and merging of the magnetic field intensity data with the bathymetric data. Math- ew’s correction was applied...

Explaining bathymetric diversity patterns in marine benthic invertebrates and demersal fishes: physiological contributions to adaptation of life at depth.

Science.gov (United States)

Brown, Alastair; Thatje, Sven

2014-05-01

Bathymetric biodiversity patterns of marine benthic invertebrates and demersal fishes have been identified in the extant fauna of the deep continental margins. Depth zonation is widespread and evident through a transition between shelf and slope fauna from the shelf break to 1000 m, and a transition between slope and abyssal fauna from 2000 to 3000 m; these transitions are characterised by high species turnover. A unimodal pattern of diversity with depth peaks between 1000 and 3000 m, despite the relatively low area represented by these depths. Zonation is thought to result from the colonisation of the deep sea by shallow-water organisms following multiple mass extinction events throughout the Phanerozoic. The effects of low temperature and high pressure act across hierarchical levels of biological organisation and appear sufficient to limit the distributions of such shallow-water species. Hydrostatic pressures of bathyal depths have consistently been identified experimentally as the maximum tolerated by shallow-water and upper bathyal benthic invertebrates at in situ temperatures, and adaptation appears required for passage to deeper water in both benthic invertebrates and demersal fishes. Together, this suggests that a hyperbaric and thermal physiological bottleneck at bathyal depths contributes to bathymetric zonation. The peak of the unimodal diversity-depth pattern typically occurs at these depths even though the area represented by these depths is relatively low. Although it is recognised that, over long evolutionary time scales, shallow-water diversity patterns are driven by speciation, little consideration has been given to the potential implications for species distribution patterns with depth. Molecular and morphological evidence indicates that cool bathyal waters are the primary site of adaptive radiation in the deep sea, and we hypothesise that bathymetric variation in speciation rates could drive the unimodal diversity-depth pattern over time. Thermal

Massachusetts Bay - Internal wave packets digitized from SAR imagery and intersected with a bathymetrically derived slope surface

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This feature class contains internal wave packets digitized from SAR imagery and intersected with a bathymetrically derived slope surface for Massachusetts Bay. The...

Bathymetric surveys at highway bridges crossing the Missouri and Mississippi Rivers near St. Louis, Missouri, 2010

Science.gov (United States)

Huizinga, Richard J.

2011-01-01

Bathymetric surveys were conducted by the U.S. Geological Survey, in cooperation with the Missouri Department of Transportation, on the Missouri and Mississippi Rivers in the vicinity of 12 bridges at 7 highway crossings near St. Louis, Missouri, in October 2010. A multibeam echo sounder mapping system was used to obtain channel-bed elevations for river reaches ranging from 3,280 to 4,590 feet long and extending across the active channel of the Missouri and Mississippi Rivers. These bathymetric scans provide a snapshot of the channel conditions at the time of the surveys and provide characteristics of scour holes that may be useful in the development of predictive guidelines or equations for scour holes. These data also may be used by the Missouri Department of Transportation to assess the bridges for stability and integrity issues with respect to bridge scour.

Prediction of topographic and bathymetric measurement performance of airborne low-SNR lidar systems

Science.gov (United States)

Cossio, Tristan

Low signal-to-noise ratio (LSNR) lidar (light detection and ranging) is an alternative paradigm to traditional lidar based on the detection of return signals at the single photoelectron level. The objective of this work was to predict low altitude (600 m) LSNR lidar system performance with regards to elevation measurement and target detection capability in topographic (dry land) and bathymetric (shallow water) scenarios. A modular numerical sensor model has been developed to provide data for further analysis due to the dearth of operational low altitude LSNR lidar systems. This simulator tool is described in detail, with consideration given to atmospheric effects, surface conditions, and the effects of laser phenomenology. Measurement performance analysis of the simulated topographic data showed results comparable to commercially available lidar systems, with a standard deviation of less than 12 cm for calculated elevation values. Bathymetric results, although dependent largely on water turbidity, were indicative of meter-scale horizontal data spacing for sea depths less than 5 m. The high prevalence of noise in LSNR lidar data introduces significant difficulties in data analysis. Novel algorithms to reduce noise are described, with particular focus on their integration into an end-to-end target detection classifier for both dry and submerged targets (cube blocks, 0.5 m to 1.0 m on a side). The key characteristic exploited to discriminate signal and noise is the temporal coherence of signal events versus the random distribution of noise events. Target detection performance over dry earth was observed to be robust, reliably detecting over 90% of targets with a minimal false alarm rate. Comparable results were observed in waters of high clarity, where the investigated system was generally able to detect more than 70% of targets to a depth of 5 m. The results of the study show that CATS, the University of Florida's LSNR lidar prototype, is capable of high fidelity

Statistical and Spatial Analysis of Bathymetric Data for the St. Clair River, 1971-2007

Science.gov (United States)

Bennion, David

2009-01-01

To address questions concerning ongoing geomorphic processes in the St. Clair River, selected bathymetric datasets spanning 36 years were analyzed. Comparisons of recent high-resolution datasets covering the upper river indicate a highly variable, active environment. Although statistical and spatial comparisons of the datasets show that some changes to the channel size and shape have taken place during the study period, uncertainty associated with various survey methods and interpolation processes limit the statistically certain results. The methods used to spatially compare the datasets are sensitive to small variations in position and depth that are within the range of uncertainty associated with the datasets. Characteristics of the data, such as the density of measured points and the range of values surveyed, can also influence the results of spatial comparison. With due consideration of these limitations, apparently active and ongoing areas of elevation change in the river are mapped and discussed.

A comparison of interpolation methods on the basis of data obtained from a bathymetric survey of Lake Vrana, Croatia

Science.gov (United States)

Šiljeg, A.; Lozić, S.; Šiljeg, S.

2015-08-01

The bathymetric survey of Lake Vrana included a wide range of activities that were performed in several different stages, in accordance with the standards set by the International Hydrographic Organization. The survey was conducted using an integrated measuring system which consisted of three main parts: a single-beam sonar HydroStar 4300 and GPS devices; a Ashtech ProMark 500 base, and a Thales Z-Max® rover. A total of 12 851 points were gathered. In order to find continuous surfaces necessary for analysing the morphology of the bed of Lake Vrana, it was necessary to approximate values in certain areas that were not directly measured, by using an appropriate interpolation method. The main aims of this research were as follows: (a) to compare the efficiency of 14 different interpolation methods and discover the most appropriate interpolators for the development of a raster model; (b) to calculate the surface area and volume of Lake Vrana, and (c) to compare the differences in calculations between separate raster models. The best deterministic method of interpolation was multiquadric RBF (radio basis function), and the best geostatistical method was ordinary cokriging. The root mean square error in both methods measured less than 0.3 m. The quality of the interpolation methods was analysed in two phases. The first phase used only points gathered by bathymetric measurement, while the second phase also included points gathered by photogrammetric restitution. The first bathymetric map of Lake Vrana in Croatia was produced, as well as scenarios of minimum and maximum water levels. The calculation also included the percentage of flooded areas and cadastre plots in the case of a 2 m increase in the water level. The research presented new scientific and methodological data related to the bathymetric features, surface area and volume of Lake Vrana.

High resolution bathymetric and sonar images of a ridge southeast of Terceira Island (Azores plateau)

Science.gov (United States)

Lourenço, N.; Miranda, J. M.; Luis, J.; Silva, I.; Goslin, J.; Ligi, M.

2003-04-01

The Terceira rift is a oblique ultra-slow spreading system where a transtensive regime results from differential movement between Eurasian and African plates. So far no classical ridge segmentation pattern has here been observed. The predominant morphological features are fault controlled rhombic shaped basins and volcanism related morphologies like circular seamounts and volcanic ridges. We present SIMRAD EM300 (bathymetry + backscatter) images acquired over one of these ridges located SE of Terceira Island, during the SIRENA cruise (PI J. Goslin), which complements previous TOBI mosaics performed over the same area during the AZZORRE99 cruise (PI M. Ligi). The ridge presents a NW-SE orientation, it is seismically active (a seismic crisis was documented in 1997) and corresponds to the southern branch of a V shape bathymetric feature enclosing the Terceira Island and which tip is located west of the Island near the 1998 Serreta ridge eruption site. NE of the ridge, the core of the V, corresponds to the North Hirondelle basin. All this area corresponds mainly to Brunhes magnetic epoch. The new bathymetry maps reveal a partition between tectonic processes, centred in the ridge, and volcanism present at the bottom of the North Hirondelle basin. The ridge high backscatter surface is cut by a set of sub-parallel anastomosed normal faults striking between N130º and N150º. Some faults present horse-tail terminations. Fault splays sometimes link to neighbour faults defining extensional duplexes and fault wedge basins and highs of rhombic shape. The faulting geometry suggests that a left-lateral strike slip component should be present. The top of the ridge consists on an arched demi-.horst, and it is probably a volcanic structure remnant (caldera system?), existing prior to onset of the tectonic stage in the ridge. Both ridge flanks display gullies and mass wasting fans at the base of the slope. The ridge vicinities are almost exclusively composed of a grayish homogeneous

Structural interpretation of the Konkan basin, southwestern continental margin of India, based on magnetic and bathymetric data

Digital Repository Service at National Institute of Oceanography (India)

Subrahmanyam, V.; Krishna, K.S.; Murty, G.P.S.; Rao, D.G.; Ramana, M.V.; Rao, M.G.

Magnetic and bathymetric studies on the Konkan basin of the southwestern continental margin of India reveal prominent NNW-SSE, NW-SE, ENE-WSW, and WNE-ESE structural trends. The crystalline basement occurs at about 5-6 km below the mean sea level. A...

The Investigation of Active Tectonism Offshore Cide-Sinop, Southern Black Sea by Seismic Reflection and Bathymetric Data

Science.gov (United States)

Alp, Y. I.; Ocakoglu, N.; Kılıc, F.; Ozel, A. O.

2017-12-01

The active tectonism offshore Cide-Sinop at the Southern Black Sea shelf area was first time investigated by multi-beam bathymetric and multi-channel seismic reflection data under the Research Project of The Scientific and Technological Research Council of Turkey (TUBİTAK-ÇAYDAG-114Y057). The multi-channel seismic reflection data of about 700 km length were acquired in 1991 by Turkish Petroleum Company (TP). Multibeam bathymetric data were collected between 2002-2008 by the Turkish Navy, Department of Navigation, Hydrography and Oceanography (TN-DNHO). Conventional data processing steps were applied as follows: in-line geometry definition, shot-receiver static correction, editing, shot muting, gain correction, CDP sorting, velocity analysis, NMO correction, muting, stacking, predictive deconvolution, band-pass filtering, finite-difference time migration, and automatic gain correction. Offshore area is represented by a quite smooth and large shelf plain with an approx. 25 km wide and the water depth of about -100 m. The shelf gently deepens and it is limited by the shelf break with average of -120 m contour. The seafloor morphology is charasterised by an erosional surface. Structurally, E-W trending strike-slip faults with generally compression components and reverse/thrust faults have been regionally mapped for the first time. Most of these faults deform all seismic units and reach the seafloor delimiting the morphological highs and submarine plains. Thus, these faults are intepreted as active faults. These results support the idea that the area is under the active compressional tectonic regime

2011 NOAA Bathymetric Lidar: U.S. Virgin Islands - St. Thomas, St. John, St. Croix (Salt River Bay, Buck Island)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data represents a LiDAR (Light Detection & Ranging) gridded bathymetric surface and a gridded relative seafloor reflectivity surface (incorporated into the...

NOAA TIFF Image - 4m Bathymetric Depth of Red Snapper Research Areas in the South Atlantic Bight, 2010

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains unified Bathymetric Depth GeoTiffs with 4x4 meter cell resolution describing the topography of 15 areas along the shelf edge off the South...

NOAA TIFF Image - 4m Bathymetric Curvature of Red Snapper Research Areas in the South Atlantic Bight, 2010

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains unified Bathymetric Curvature GeoTiffs with 4x4 meter cell resolution describing the topography of 15 areas along the shelf edge off the South...

AtlantOS WP2, Enhancement of ship-based observing networks - Bathymetric integration and visualization of Europe's data holdings

Science.gov (United States)

Wölfl, Anne-Cathrin; Devey, Colin; Augustin, Nico

2017-04-01

The European Horizon 2020 research and innovation project AtlantOS - Optimising and Enhancing the Integrated Atlantic Ocean Observing Systems - aims to improve the present-day ocean observing activities in the Atlantic Ocean by establishing a sustainable, efficient and integrated Atlantic Ocean Observing System. 62 partners from 18 countries are working on solutions I) to improve international collaboration in the design, implementation and benefit sharing of ocean observing, II) to promote engagement and innovation in all aspects of ocean observing, III) to facilitate free and open access to ocean data and information, IV) to enable and disseminate methods of achieving quality and authority of ocean information, V) to strengthen the Global Ocean Observing System (GOOS) and to sustain observing systems that are critical for the Copernicus Marine Environment Monitoring Service and its applications and VI) to contribute to the aims of the Galway Statement on Atlantic Ocean Cooperation. The Work Package 2 of the AtlantOS project focuses on improving, expanding, integrating and innovating ship-based observations. One of the tasks is the provision of Europe's existing and future bathymetric data sets from the Atlantic Ocean in accessible formats enabling easy processing and visualization for stakeholders. Furthermore, a new concept has recently been implemented, where three large German research vessels continuously collect bathymetric data during their transits. All data sets are gathered and processed with the help of national data centers and partner institutions and integrated into existing open access data systems, such as Pangaea in Germany, EMODnet at European level and GMRT (Global Multi-Resolution Topography synthesis) at international level. The processed data will be linked to the original data holdings, that can easily be accessed if required. The overall aim of this task is to make bathymetric data publicly available for specialists and non-specialists both

NOAA TIFF Image - 4m Bathymetric Depth Range of Red Snapper Research Areas in the South Atlantic Bight, 2010

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains unified Bathymetric Depth Range GeoTiffs with 4x4 meter cell resolution describing the topography of 15 areas along the shelf edge off the...

NOAA TIFF Image - 4m Bathymetric Mean Depth of Red Snapper Research Areas in the South Atlantic Bight, 2010

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains unified Bathymetric Mean Depth GeoTiffs with 4x4 meter cell resolution describing the topography of 15 areas along the shelf edge off the South...

Bathymetric and velocimetric surveys at highway bridges crossing the Missouri River in and into Missouri during summer flooding, July-August 2011

Science.gov (United States)

Huizinga, Richard J.

2012-01-01

, and comparisons between bathymetric surfaces from the previous surveys and those of this study indicate substantial variability in the response of the channel bed to the 2011 summer flood conditions. At sites in Kansas City, there was no consistent deepening of the channel or increase in the size of scour holes, despite substantially more discharge and a higher water-surface elevation in the 2011 surveys, which implies the high-flow conditions during the 2011 surveys created a similar scour scenario to the previous surveys. At Jefferson City and the St. Louis sites, there was a consistent deepening of the channel, and a slight to substantial increase in the depth of scour holes in the 2011 surveys compared to previous surveys, although the effects of the higher flow appeared to be mitigated by the shape and alignment of the piers at most sites in St. Louis. Construction activities related to a new bridge at the Atchison, Kansas, site likely have contributed to the substantial additional scour observed there in a previous survey during the 2010 flooding, and the subsequent aggradation of the channel bed observed in the 2011 survey. Pier size, nose shape, and alignment to flow also had a profound effect on the size of the scour hole observed for a given pier.

Estuarine Bathymetric Digital Elevation Models (30 meter and 3 arc second resolution) Derived From Source Hydrographic Survey Soundings Collected by NOAA

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — These Bathymetric Digital Elevation Models (DEM) were generated from original point soundings collected during hydrographic surveys conducted by the National Ocean...

Bathymetric Signatures of Oceanic Detachment Faulting and Potential Ultramafic Lithologies at Outcrop or in the Shallow Subseafloor

Science.gov (United States)

Cann, J. R.; Smith, D. K.; Escartin, J.; Schouten, H.

2008-12-01

For ten years, domal bathymetric features capped by corrugated and striated surfaces have been recognized as exposures of oceanic detachment faults, and hence potentially as exposures of plutonic rocks from lower crust or upper mantle. Associated with these domes are other bathymetric features that indicate the presence of detachment faulting. Taken together these bathymetric signatures allow the mapping of large areas of detachment faulting at slow and intermediate spreading ridges, both at the axis and away from it. These features are: 1. Smooth elevated domes corrugated parallel to the spreading direction, typically 10-30 km wide parallel to the axis; 2. Linear ridges with outward-facing slopes steeper than 20°, running parallel to the spreading axis, typically 10-30 km long; 3. Deep basins with steep sides and relatively flat floors, typically 10-20 km long parallel to the spreading axis and 5-10 km wide. This characteristic bathymetric association arises from the rolling over of long-lived detachment faults as they spread away from the axis. The faults dip steeply close to their origin at a few kilometers depth near the spreading axis, and rotate to shallow dips as they continue to evolve, with associated footwall flexure and rotation of rider blocks carried on the fault surface. The outward slopes of the linear ridges can be shown to be rotated volcanic seafloor transported from the median valley floor. The basins may be formed by the footwall flexure, and may be exposures of the detachment surface. Critical in this analysis is that the corrugated domes are not the only sites of detachment faulting, but are the places where higher parts of much more extensive detachment faults happen to be exposed. The fault plane rises and falls along axis, and in some places is covered by rider blocks, while in others it is exposed at the sea floor. We use this association to search for evidence for detachment faulting in existing surveys, identifying for example an area

Qualitative simulation of bathymetric changes due to reservoir sedimentation: A Japanese case study.

Directory of Open Access Journals (Sweden)

Ahmed Bilal

Full Text Available Sediment-dynamics modeling is a useful tool for estimating a dam's lifespan and its cost-benefit analysis. Collecting real data for sediment-dynamics analysis from conventional field survey methods is both tedious and expensive. Therefore, for most rivers, the historical record of data is either missing or not very detailed. Available data and existing tools have much potential and may be used for qualitative prediction of future bathymetric change trend. This study shows that proxy approaches may be used to increase the spatiotemporal resolution of flow data, and hypothesize the river cross-sections and sediment data. Sediment-dynamics analysis of the reach of the Tenryu River upstream of Sakuma Dam in Japan was performed to predict its future bathymetric changes using a 1D numerical model (HEC-RAS. In this case study, only annually-averaged flow data and the river's longitudinal bed profile at 5-year intervals were available. Therefore, the other required data, including river cross-section and geometry and sediment inflow grain sizes, had to be hypothesized or assimilated indirectly. The model yielded a good qualitative agreement, with an R2 (coefficient of determination of 0.8 for the observed and simulated bed profiles. A predictive simulation demonstrated that the useful life of the dam would end after the year 2035 (±5 years, which is in conformity with initial detailed estimates. The study indicates that a sediment-dynamic analysis can be performed even with a limited amount of data. However, such studies may only assess the qualitative trends of sediment dynamics.

Qualitative simulation of bathymetric changes due to reservoir sedimentation: A Japanese case study.

Science.gov (United States)

Bilal, Ahmed; Dai, Wenhong; Larson, Magnus; Beebo, Qaid Naamo; Xie, Qiancheng

2017-01-01

Sediment-dynamics modeling is a useful tool for estimating a dam's lifespan and its cost-benefit analysis. Collecting real data for sediment-dynamics analysis from conventional field survey methods is both tedious and expensive. Therefore, for most rivers, the historical record of data is either missing or not very detailed. Available data and existing tools have much potential and may be used for qualitative prediction of future bathymetric change trend. This study shows that proxy approaches may be used to increase the spatiotemporal resolution of flow data, and hypothesize the river cross-sections and sediment data. Sediment-dynamics analysis of the reach of the Tenryu River upstream of Sakuma Dam in Japan was performed to predict its future bathymetric changes using a 1D numerical model (HEC-RAS). In this case study, only annually-averaged flow data and the river's longitudinal bed profile at 5-year intervals were available. Therefore, the other required data, including river cross-section and geometry and sediment inflow grain sizes, had to be hypothesized or assimilated indirectly. The model yielded a good qualitative agreement, with an R2 (coefficient of determination) of 0.8 for the observed and simulated bed profiles. A predictive simulation demonstrated that the useful life of the dam would end after the year 2035 (±5 years), which is in conformity with initial detailed estimates. The study indicates that a sediment-dynamic analysis can be performed even with a limited amount of data. However, such studies may only assess the qualitative trends of sediment dynamics.

Subducted bathymetric features linked to variations in earthquake apparent stress along the northern Japan Trench

Science.gov (United States)

Moyer, P. A.; Bilek, S. L.; Phillips, W. S.

2010-12-01

Ocean floor bathymetric features such as seamounts and ridges are thought to influence the earthquake rupture process when they enter the subduction zone by causing changes in frictional conditions along the megathrust contact between the subducting and overriding plates. Once subducted, these features have been described as localized areas of heterogeneous plate coupling, with some controversy over whether these features cause an increase or decrease in interplate coupling. Along the northern Japan Trench, a number of bathymetric features, such as horst and graben structures and seamounts, enter the subduction zone where they may vary earthquake behavior. Using seismic coda waves, scattered energy following the direct wave arrivals, we compute apparent stress (a measure of stress drop proportional to radiated seismic energy that has been tied to the strength of the fault interface contact) for 329 intermediate magnitude (3.2 earthquake spectra for path and site effects and compute apparent stress using the seismic moment and corner frequency determined from the spectra. Preliminary results indicate apparent stress values between 0.3 - 22.6 MPa for events over a depth range of 2 - 55 km, similar to those found in other studies of the region although within a different depth range, with variations both along-strike and downdip. Off the Sanriku Coast, horst and graben structures enter the Japan Trench in an area where a large number of earthquakes occur at shallow (< 30 km) depth. These shallow events have a mean apparent stress of 1.2 MPa (range 0.3 - 3.8 MPa) which is approximately 2 times lower then the mean apparent stress for other events along the northern portion of this margin in the same shallow depth range. The relatively low apparent stress for events related to subducting horst and graben structures suggests weak interplate coupling between the subducting and overriding plates due to small, irregular contact zones with these features at depth. This is in

NOAA TIFF Image - 4m Bathymetric Principal Component Analysis (PCA) of Red Snapper Research Areas in the South Atlantic Bight, 2010

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains unified Bathymetric PCA GeoTiffs with 4x4 meter cell resolution describing the topography of 15 areas along the shelf edge off the South...

Bathymetric and velocimetric surveys at highway bridges crossing the Missouri River between Kansas City and St. Louis, Missouri, April-May, 2013

Science.gov (United States)

Huizinga, Richard J.

2014-01-01

Bathymetric and velocimetric data were collected by the U.S. Geological Survey, in cooperation with the Missouri Department of Transportation, in the vicinity of 10 bridges at 9 highway crossings of the Missouri River between Lexington and Washington, Missouri, from April 22 through May 2, 2013. A multibeam echosounder mapping system was used to obtain channel-bed elevations for river reaches ranging from 1,640 to 1,840 feet longitudinally and extending laterally across the active channel between banks and spur dikes in the Missouri River during low- to moderate-flow conditions. These bathymetric surveys indicate the channel conditions at the time of the surveys and provide characteristics of scour holes that may be useful in the development of predictive guidelines or equations for scour holes. These data also may be useful to the Missouri Department of Transportation to assess the bridges for stability and integrity issues with respect to bridge scour during floods. Bathymetric data were collected around every pier that was in water, except those at the edge of water or in very shallow water (less than about 6 feet). Scour holes were present at most piers for which bathymetry could be obtained, except at piers on channel banks, near or embedded in lateral or longitudinal spur dikes, and on exposed bedrock outcrops. Scour holes observed at the surveyed bridges were examined with respect to depth and shape. Although exposure of parts of foundational support elements was observed at several piers, at most sites the exposure likely can be considered minimal compared to the overall substructure that remains buried in channel-bed material; however, there were several notable exceptions where the bed material thickness between the bottom of the scour hole and bedrock was less than 6 feet. Such substantial exposure of usually buried substructural elements may warrant special observation in future flood events. Previous bathymetric surveys had been done at all of the

Bathymetric and velocimetric surveys at highway bridges crossing the Missouri River near Kansas City, Missouri, June 2–4, 2015

Science.gov (United States)

Huizinga, Richard J.

2016-06-22

Bathymetric and velocimetric data were collected by the U.S. Geological Survey, in cooperation with the Missouri Department of Transportation, near 8 bridges at 7 highway crossings of the Missouri River in Kansas City, Missouri, from June 2 to 4, 2015. A multibeam echosounder mapping system was used to obtain channel-bed elevations for river reaches ranging from 1,640 to 1,660 feet longitudinally and extending laterally across the active channel from bank to bank during low to moderate flood flow conditions. These bathymetric surveys indicate the channel conditions at the time of the surveys and provide characteristics of scour holes that may be useful in the development of predictive guidelines or equations for scour holes. These data also may be useful to the Missouri Department of Transportation as a low to moderate flood flow comparison to help assess the bridges for stability and integrity issues with respect to bridge scour during floods.

Bathymetric and velocimetric surveys at highway bridges crossing the Missouri and Mississippi Rivers on the periphery of Missouri, June 2014

Science.gov (United States)

Huizinga, Richard J.

2015-01-01

Bathymetric and velocimetric data were collected by the U.S. Geological Survey, in cooperation with the Missouri Department of Transportation, in the vicinity of 8 bridges at 7 highway crossings of the Missouri and Mississippi Rivers on the periphery of Missouri from June 3 to 11, 2014. A multibeam echosounder mapping system was used to obtain channel-bed elevations for river reaches ranging from 1,525 to 1,640 feet longitudinally, and extending laterally across the active channel from bank to bank during low- to moderate-flow conditions. These bathymetric surveys indicate the channel conditions at the time of the surveys and provide characteristics of scour holes that may be useful in the development of predictive guidelines or equations for scour holes. These data also may be useful to the Missouri Department of Transportation as a low- to moderate-flow comparison to help assess the bridges for stability and integrity issues with respect to bridge scour during floods.

Historical bathymetry and bathymetric change in the Mississippi-Alabama coastal region, 1847-2009

Science.gov (United States)

Buster, Noreen A.; Morton, Robert A.

2011-01-01

Land loss and seafloor change around the Mississippi and Alabama (MS-AL) barrier islands are of great concern to the public and to local, state, and federal agencies. The islands provide wildlife protected areas and recreational land, and they serve as a natural first line of defense for the mainland against storm activity (index map on poster). Principal physical conditions that drive morphological seafloor and coastal change in this area include decreased sediment supply, sea-level rise, storms, and human activities (Otvos, 1970; Byrnes and others, 1991; Morton and others, 2004; Morton, 2008). Seafloor responses to the same processes can also affect the entire coastal zone. Sediment eroded from the barrier islands is entrained in the littoral system, where it is redistributed by alongshore currents. Wave and current activity is partially controlled by the profile of the seafloor, and this interdependency along with natural and anthropogenic influences has significant effects on nearshore environments. When a coastal system is altered by human activity such as dredging, as is the case of the MS-AL coastal region, the natural state and processes are altered, and alongshore sediment transport can be disrupted. As a result of deeply dredged channels, adjacent island migration is blocked, nearshore environments downdrift in the littoral system become sediment starved, and sedimentation around the channels is modified. Sediment deposition and erosion are reflected through seafloor evolution. In a rapidly changing coastal environment, understanding historically where and why changes are occurring is essential. To better assess the comprehensive dynamics of the MS-AL coastal zone, a 160-year evaluation of the bathymetry and bathymetric change of the region was conducted.

Structural and stratigraphic constraints on tsunamigenic rupture along the frontal Sunda megathrust from MegaTera bathymetric and seismic reflection data

Science.gov (United States)

Bradley, K. E.; Qin, Y.; Villanueva-Robles, F.; Hananto, N.; Leclerc, F.; Singh, S. C.; Tapponnier, P.; Sieh, K.; Wei, S.; Carton, H. D.; Permana, H.; Avianto, P.; Nugroho, A. B.

2017-12-01

The joint EOS/IPG/LIPI 2015 MegaTera expedition collected high-resolution seismic reflection profiles and bathymetric data across the Sunda trench, updip of the Mw7.7, 2010 Mentawai tsunami-earthquake rupture patch. These data reveal rapid lateral variations in both the stratigraphic level of the frontal Sunda megathrust and the vergence of frontal ramp faults. The stratigraphic depth of the megathrust at the deformation front correlates with ramp-thrust vergence and with changes in the basal friction angle inferred by critical-taper wedge theory. Where ramp thrusts verge uniformly seaward and have an average dip of 30°, the megathrust decollement resides atop a high-amplitude reflector that marks the inferred top of pelagic sediments. Where ramp thrusts are bi-vergent (similar throw on both landward- and seaward-vergent faults) and have an average dip of 42°, the decollement is higher, within the incoming clastic sequence, above a seismically transparent unit inferred to represent distal fan muds. Where ramp thrusts are uniformly landward vergent, the decollement sits directly on top of the oceanic crust that forms the bathymetrically prominent, subducting Investigator Ridge. The two, separate regions of large tsunamigenic ground-surface uplift during the 2010 tsunami earthquake that have been inferred from joint inversions of seismic, GPS, and tsunami data (e.g. Yue et al., 2014; Satake et al., 2013) correspond to the areas of frontal bi-vergence in the MegaTera data. We propose that enhanced surface uplift and tsunamigenesis during this event occurred when rupture propagated onto areas where the decollement sits directly above the basal muds of the incoming clastic sequence. Thus we hypothesize that frontal bi-vergence may mark areas of enhanced tsunami hazard posed by small magnitude, shallow megathrust ruptures that propagate to the trench. [Yue, H. et al., 2014, Rupture process of the…, JGR 119 doi:10.1002/2014JB011082; Satake, K. et al., 2013, Tsunami

Anthropogenic influence on recent bathymetric change in west-central San Francisco Bay

Science.gov (United States)

Barnard, Patrick L.; Kvitek, Rikk G.

2010-01-01

Two multibeam sonar surveys of west-central San Francisco Bay, California, were conducted in 1997 and 2008. Bathymetric change analysis between the two surveys indicates a loss of 14.1 million cubic meters (-3.1 cm/yr-1) of sediment during this time period, representing an approximately three-fold acceleration of the rate that was observed from prior depth change analysis from 1947 to 1979 for all of Central Bay, using more spatially coarse National Ocean Service (NOS) soundings. The portions of the overlapping survey areas between 1997 and 2008 designated as aggregate mining lease sites lost sediment at five times the rate of the remainder of west-central San Francisco Bay. Despite covering only 28% of the analysis area, volume change within leasing areas accounted for 9.2 million cubic meters of sediment loss, while the rest of the area lost 4.9 million cubic meters of sediment. The uncertainty of this recent analysis is more tightly constrained due to more stringent controls on vertical and horizontal position via tightly coupled, inertially aided differential Global Positioning Systems (GPS) solutions for survey vessel trajectory that virtually eliminate inaccuracies from traditional tide modeling and vessel motion artifacts. Further, quantification of systematic depth measurement error can now be calculated through comparison of static surfaces (e.g., bedrock) between surveys using seafloor habitat maps based on acoustic backscatter measurements and ground-truthing with grab samples and underwater video. Sediment loss in the entire San Francisco Bay Coastal System during the last half-century,as estimated from a series of bathymetric change studies, is 240 million cubic meters, and most of this is believed to be coarse sediment (i.e., sand and gravel) from Central Bay and the San Francisco Bar, which is likely to limit the sand supply to adjacent, open-coast beaches. This hypothesis is supported by a calibrated numerical model in a related study that indicates

Volcanic and Hydrothermal Activity of the North Su Volcano: New Insights from Repeated Bathymetric Surveys and ROV Observations

Science.gov (United States)

Thal, J.; Bach, W.; Tivey, M.; Yoerger, D.

2013-12-01

Bathymetric data from cruises in 2002, 2006, and 2011 were combined and compared to determine the evolution of volcanic activity, seafloor structures, erosional features and to identify and document the distribution of hydrothermal vents on North Su volcano, SuSu Knolls, eastern Manus Basin (Papua New Guinea). Geologic mapping based on ROV observations from 2006 (WHOI Jason-2) and 2011 (MARUM Quest-4000) combined with repeated bathymetric surveys from 2002 and 2011 are used to identify morphologic features on the slopes of North Su and to track temporal changes. ROV MARUM Quest-4000 bathymetry was used to develop a 10 m grid of the top of North Su to precisely depict recent changes. In 2006, the south slope of North Su was steeply sloped and featured numerous white smoker vents discharging acid sulfate waters. These vents were covered by several tens of meters of sand- to gravel-sized volcanic material in 2011. The growth of this new cone changed the bathymetry of the south flank of North Su up to ~50 m and emplaced ~0.014 km3 of clastic volcanic material. This material is primarily comprised of fractured altered dacite and massive fresh dacite as well as crystals of opx, cpx, olivine and plagioclase. There is no evidence for pyroclastic fragmentation, so we hypothesize that the fragmentation is likely related to hydrothermal explosions. Hydrothermal activity varies over a short (~50 m) lateral distance from 'flashing' black smokers to acidic white smoker vents. Within 2 weeks of observation time in 2011, the white smoker vents varied markedly in activity suggesting a highly episodic hydrothermal system. Based on ROV video recordings, we identified steeply sloping (up to 30°) slopes exposing pillars and walls of hydrothermal cemented volcaniclastic material representing former fluid upflow zones. These features show that hydrothermal activity has increased slope stability as hydrothermal cementation has prevented slope collapse. Additionally, in some places

Evaluation of LiDAR-acquired bathymetric and topographic data accuracy in various hydrogeomorphic settings in the Deadwood and South Fork Boise Rivers, West-Central Idaho, 2007

Science.gov (United States)

Skinner, Kenneth D.

2011-01-01

High-quality elevation data in riverine environments are important for fisheries management applications and the accuracy of such data needs to be determined for its proper application. The Experimental Advanced Airborne Research LiDAR (Light Detection and Ranging)-or EAARL-system was used to obtain topographic and bathymetric data along the Deadwood and South Fork Boise Rivers in west-central Idaho. The EAARL data were post-processed into bare earth and bathymetric raster and point datasets. Concurrently with the EAARL surveys, real-time kinematic global positioning system surveys were made in three areas along each of the rivers to assess the accuracy of the EAARL elevation data in different hydrogeomorphic settings. The accuracies of the EAARL-derived raster elevation values, determined in open, flat terrain, to provide an optimal vertical comparison surface, had root mean square errors ranging from 0.134 to 0.347 m. Accuracies in the elevation values for the stream hydrogeomorphic settings had root mean square errors ranging from 0.251 to 0.782 m. The greater root mean square errors for the latter data are the result of complex hydrogeomorphic environments within the streams, such as submerged aquatic macrophytes and air bubble entrainment; and those along the banks, such as boulders, woody debris, and steep slopes. These complex environments reduce the accuracy of EAARL bathymetric and topographic measurements. Steep banks emphasize the horizontal location discrepancies between the EAARL and ground-survey data and may not be good representations of vertical accuracy. The EAARL point to ground-survey comparisons produced results with slightly higher but similar root mean square errors than those for the EAARL raster to ground-survey comparisons, emphasizing the minimized horizontal offset by using interpolated values from the raster dataset at the exact location of the ground-survey point as opposed to an actual EAARL point within a 1-meter distance. The

Bathymetric and longitudinal distribution analyysis of the rockfish Helicolenus Dactylopterus (Delaroche, 1809 in the southern Tyrrhenian Sea (central Mediterranean

Directory of Open Access Journals (Sweden)

T. ROMEO

2009-06-01

Full Text Available This study provides information on bathymetric and longitudinal distribution heterogeneity of the rockfish Helicolenus dactylopterus in the southern Tyrrhenian Sea. Data were drawn from experimental bottom trawl (1996-2002 plus bottom trap (2001-02 surveys. The frequency of occurrence and mean relative density (N/km2 and biomass (kg/km2 indexes were calculated for two survey seasons (spring and autumn, four geographic sectors and three depth strata. MANOVA was used to test fish abundance among years, sectors and strata. Analysis of the length-frequency distributions was carried out by two-way (gears and depths ANOVA, post hoc multiple comparisons for testing differences among depths and Student’s t test for testing differences between gears. Length-weight relationship was also estimated and the allometric coefficient was tested with the Student’s t test. The results showed a significant positive bathymetric gradient of sizes both for trawl and trap surveys; at same depths, fish caught by traps were significantly longer than those caught by trawl. In spring surveys, significant differences were found among strata for both abundance indexes; in autumn surveys, significant differences between depth strata were found only for density indices. The distribution and abundance patterns of H. dactylopterus along the southern Tyrrhenian Sea was homogeneous among sectors. Length-weight relationship showed a significant positive allometric growth.

Bathymetric and velocimetric surveys at highway bridges crossing the Missouri and Mississippi Rivers near St. Louis, Missouri, May 23–27, 2016

Science.gov (United States)

Huizinga, Richard J.

2017-09-26

Bathymetric and velocimetric data were collected by the U.S. Geological Survey, in cooperation with the Missouri Department of Transportation, near 13 bridges at 8 highway crossings of the Missouri and Mississippi Rivers in the greater St. Louis, Missouri, area from May 23 to 27, 2016. A multibeam echosounder mapping system was used to obtain channel-bed elevations for river reaches ranging from 1,640 to 1,970 feet longitudinally and extending laterally across the active channel from bank to bank during low to moderate flood flow conditions. These bathymetric surveys indicate the channel conditions at the time of the surveys and provide characteristics of scour holes that may be useful in the development of predictive guidelines or equations for scour holes. These data also may be useful to the Missouri Department of Transportation as a low to moderate flood flow comparison to help assess the bridges for stability and integrity issues with respect to bridge scour during floods.Bathymetric data were collected around every pier that was in water, except those at the edge of water, and scour holes were observed at most surveyed piers. The observed scour holes at the surveyed bridges were examined with respect to shape and depth.The frontal slope values determined for scour holes observed in the current (2016) study generally are similar to recommended values in the literature and to values determined for scour holes in previous bathymetric surveys. Several of the structures had piers that were skewed to primary approach flow, as indicated by the scour hole being longer on the side of the pier with impinging flow, and some amount of deposition on the leeward side, as typically has been observed at piers skewed to approach flow; however, at most skewed piers in the current (2016) study, the scour hole was deeper on the leeward side of the pier. At most of these piers, the angled approach flow was the result of a deflection or contraction of flow caused by a spur dike

Interpretation of bathymetric and magnetic data from the easternmost segment of Australian-Antarctic Ridge, 156°-161°E

Science.gov (United States)

Choi, H.; Kim, S.; Park, S.

2013-12-01

From 2011 to 2013, Korea Polar Research Institute (KOPRI) conducted a series of geophysical and geochemical expeditions on the longest and easternmost segment of Australian-Antarctic Ridge, located at 61°-63°S, and 156°-161°E. This ridge segment plays an important role in constraining the tectonics of the Antarctic plate. Using IBRV ARAON, the detailed bathymetric data and eleven total magnetic profiles were collected. The studied ridge has spread NNW-SSE direction and tends to be shallower to the west and deeper to the east. The western side of the ridge (156°-157.50°E) shows a broad axial high and a plenty of seamounts as an indicative of massive volcanism. Near the center of the ridge (158°-159°E), a seamount chain is formed stretching toward the south from the ridge. Also, the symmetric seafloor fabric is clearly observed at the eastern portion (158.50°-160°E) of the seamount chain. From the topographic change along the ridge axis, the western part of the ridge appears to have a sufficient magma supply. On the contrary, the eastern side of the ridge (160°-161°E) is characterized by axial valley and relatively deeper depth. Nevertheless, the observed total magnetic field anomalies exhibit symmetric patterns across the ridge axis. Although there have not been enough magnetic survey lines, the spreading rates of the ridge are estimated as the half-spreading rate of 37.7 mm/y and 35.3 mm/y for the western portion of the ridge and 42.3 mm/y for the eastern portion. The studied ridge can be categorized as an intermediate spreading ridge, confirming previous studies based on the spreading rate of global ridge system. Here we will present the preliminary results on bathymetric changes along the ridge axis and its relationship with melt supply distribution, and detailed magnetic properties of the ridge constrained by the observed total field anomalies.

Vertical water mass structure in the North Atlantic influences the bathymetric distribution of species in the deep-sea coral genus Paramuricea

Science.gov (United States)

Radice, Veronica Z.; Quattrini, Andrea M.; Wareham, Vonda E.; Edinger, Evan N.; Cordes, Erik E.

2016-10-01

Deep-sea corals are the structural foundation of their ecosystems along continental margins worldwide, yet the factors driving their broad distribution are poorly understood. Environmental factors, especially depth-related variables including water mass properties, are thought to considerably affect the realized distribution of deep-sea corals. These factors are governed by local and regional oceanographic conditions that directly influence the dispersal of larvae, and therefore affect the ultimate distribution of adult corals. We used molecular barcoding of mitochondrial and nuclear sequences to identify species of octocorals in the genus Paramuricea collected from the Labrador Sea to the Grand Banks of Newfoundland, Canada at depths of 150-1500 m. The results of this study revealed overlapping bathymetric distributions of the Paramuricea species present off the eastern Canadian coast, including the presence of a few cryptic species previously designated as Paramuricea placomus. The distribution of Paramuricea species in the western North Atlantic differs from the Gulf of Mexico, where five Paramuricea species exhibit strong segregation by depth. The different patterns of Paramuricea species in these contrasting biogeographic regions provide insight into how water mass structure may shape species distribution. Investigating Paramuricea prevalence and distribution in conjunction with oceanographic conditions can help demonstrate the factors that generate and maintain deep-sea biodiversity.

Bathymetric surveys at highway bridges crossing the Missouri River in Kansas City, Missouri, using a multibeam echo sounder, 2010

Science.gov (United States)

Huizinga, Richard J.

2010-01-01

Bathymetric surveys were conducted by the U.S. Geological Survey, in cooperation with the Missouri Department of Transportation, on the Missouri River in the vicinity of nine bridges at seven highway crossings in Kansas City, Missouri, in March 2010. A multibeam echo sounder mapping system was used to obtain channel-bed elevations for river reaches that ranged from 1,640 to 1,800 feet long and extending from bank to bank in the main channel of the Missouri River. These bathymetric scans will be used by the Missouri Department of Transportation to assess the condition of the bridges for stability and integrity with respect to bridge scour. Bathymetric data were collected around every pier that was in water, except those at the edge of the water or in extremely shallow water, and one pier that was surrounded by a large debris raft. A scour hole was present at every pier for which bathymetric data could be obtained. The scour hole at a given pier varied in depth relative to the upstream channel bed, depending on the presence and proximity of other piers or structures upstream from the pier in question. The surveyed channel bed at the bottom of the scour hole was between 5 and 50 feet above bedrock. At bridges with drilled shaft foundations, generally there was exposure of the upstream end of the seal course and the seal course often was undermined to some extent. At one site, the minimum elevation of the scour hole at the main channel pier was about 10 feet below the bottom of the seal course, and the sides of the drilled shafts were evident in a point cloud visualization of the data at that pier. However, drilled shafts generally penetrated 20 feet into bedrock. Undermining of the seal course was evident as a sonic 'shadow' in the point cloud visualization of several of the piers. Large dune features were present in the channel at nearly all of the surveyed sites, as were numerous smaller dunes and many ripples. Several of the sites are on or near bends in the river

High Power, Thermally Optimized Blue Laser for Lidar, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — To enable widespread and rapid airborne bathymetric lidar to adequate depths in many ocean regions a low-cost, rugged, and high energy pulsed laser source must be...

High Power, Thermally Optimized Blue Laser for Lidar, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — To enable widespread and rapid airborne bathymetric lidar to adequate depths in many ocean regions a low-cost, rugged, and high energy pulsed laser source must be...

Integrating Sensors into a Marine Drone for Bathymetric 3D Surveys in Shallow Waters

Science.gov (United States)

Giordano, Francesco; Mattei, Gaia; Parente, Claudio; Peluso, Francesco; Santamaria, Raffaele

2015-01-01

This paper demonstrates that accurate data concerning bathymetry as well as environmental conditions in shallow waters can be acquired using sensors that are integrated into the same marine vehicle. An open prototype of an unmanned surface vessel (USV) named MicroVeGA is described. The focus is on the main instruments installed on-board: a differential Global Position System (GPS) system and single beam echo sounder; inertial platform for attitude control; ultrasound obstacle-detection system with temperature control system; emerged and submerged video acquisition system. The results of two cases study are presented, both concerning areas (Sorrento Marina Grande and Marechiaro Harbour, both in the Gulf of Naples) characterized by a coastal physiography that impedes the execution of a bathymetric survey with traditional boats. In addition, those areas are critical because of the presence of submerged archaeological remains that produce rapid changes in depth values. The experiments confirm that the integration of the sensors improves the instruments’ performance and survey accuracy. PMID:26729117

Integrating Sensors into a Marine Drone for Bathymetric 3D Surveys in Shallow Waters.

Science.gov (United States)

Giordano, Francesco; Mattei, Gaia; Parente, Claudio; Peluso, Francesco; Santamaria, Raffaele

2015-12-29

This paper demonstrates that accurate data concerning bathymetry as well as environmental conditions in shallow waters can be acquired using sensors that are integrated into the same marine vehicle. An open prototype of an unmanned surface vessel (USV) named MicroVeGA is described. The focus is on the main instruments installed on-board: a differential Global Position System (GPS) system and single beam echo sounder; inertial platform for attitude control; ultrasound obstacle-detection system with temperature control system; emerged and submerged video acquisition system. The results of two cases study are presented, both concerning areas (Sorrento Marina Grande and Marechiaro Harbour, both in the Gulf of Naples) characterized by a coastal physiography that impedes the execution of a bathymetric survey with traditional boats. In addition, those areas are critical because of the presence of submerged archaeological remains that produce rapid changes in depth values. The experiments confirm that the integration of the sensors improves the instruments' performance and survey accuracy.

Combining Cluster Analysis and Small Unmanned Aerial Systems (sUAS) for Accurate and Low-cost Bathymetric Surveying

Science.gov (United States)

Maples, B. L.; Alvarez, L. V.; Moreno, H. A.; Chilson, P. B.; Segales, A.

2017-12-01

Given that classical in-situ direct surveying for geomorphological subsurface information in rivers is time-consuming, labor-intensive, costly, and often involves high-risk activities, it is obvious that non-intrusive technologies, like UAS-based, LIDAR-based remote sensing, have a promising potential and benefits in terms of efficient and accurate measurement of channel topography over large areas within a short time; therefore, a tremendous amount of attention has been paid to the development of these techniques. Over the past two decades, efforts have been undertaken to develop a specialized technique that can penetrate the water body and detect the channel bed to derive river and coastal bathymetry. In this research, we develop a low-cost effective technique for water body bathymetry. With the use of a sUAS and a light-weight sonar, the bathymetry and volume of a small reservoir have been surveyed. The sUAS surveying approach is conducted under low altitudes (2 meters from the water) using the sUAS to tow a small boat with the sonar attached. A cluster analysis is conducted to optimize the sUAS data collection and minimize the standard deviation created by under-sampling in areas of highly variable bathymetry, so measurements are densified in regions featured by steep slopes and drastic changes in the reservoir bed. This technique provides flexibility, efficiency, and free-risk to humans while obtaining high-quality information. The irregularly-spaced bathymetric survey is then interpolated using unstructured Triangular Irregular Network (TIN)-based maps to avoid re-gridding or re-sampling issues.

Geophysical study of a seamount located on the continental margin of India

Digital Repository Service at National Institute of Oceanography (India)

Bhattacharya, G.C.; Subrahmanyam, V.

Bathymetric, magnetic, and gravity data obtained over a 2,464 m high seamount located in the Arabian Sea indicate that the seamount (inferred mean density = 2.65 gm/cc) extends for 1 km beneath the seafloor and is locally isostatically compensated...

Evolutionary transitions in symbioses: dramatic reductions in bathymetric and geographic ranges of Zoanthidea coincide with loss of symbioses with invertebrates.

Science.gov (United States)

Swain, Timothy D

2010-06-01

Two fundamental symbiosis-based trophic types are recognized among Zoanthidea (Cnidaria, Anthozoa): fixed carbon is either obtained directly from zooxanthellae photosymbionts or from environmental sources through feeding with the assistance of host-invertebrate behaviour and structure. Each trophic type is characteristic of the suborders of Zoanthidea and is associated with substantial distributional asymmetries: suborder Macrocnemina are symbionts of invertebrates and have global geographic and bathymetric distributions and suborder Brachycnemina are hosts of endosymbiotic zooxanthellae and are restricted to tropical photic zones. While exposure to solar radiation could explain the bathymetric asymmetry it does not explain the geographic asymmetry, nor is it clear why evolutionary transitions to the zooxanthellae-free state have apparently occurred within Macrocnemina but not within Brachycnemina. To better understand the transitions between symbiosis-based trophic types of Zoanthidea, a concatenated data set of nuclear and mitochondrial nucleotide sequences were used to test hypotheses of monophyly for groups defined by morphology and symbiosis, and to reconstruct the evolutionary transitions of morphological and symbiotic characters. The results indicate that the morphological characters that define Macrocnemina are plesiomorphic and the characters that define its subordinate taxa are homoplasious. Symbioses with invertebrates have ancient and recent transitions with a general pattern of stability in host associations through evolutionary time. The reduction in distribution of Zoanthidea is independent of the evolution of zooxanthellae symbiosis and consistent with hypotheses of the benefits of invertebrate symbioses, indicating that the ability to persist in most habitats may have been lost with the termination of symbioses with invertebrates.

Coastal Digital Elevation Models (DEMs) for tsunami hazard assessment on the French coasts

Science.gov (United States)

Maspataud, Aurélie; Biscara, Laurie; Hébert, Hélène; Schmitt, Thierry; Créach, Ronan

2015-04-01

Building precise and up-to-date coastal DEMs is a prerequisite for accurate modeling and forecasting of hydrodynamic processes at local scale. Marine flooding, originating from tsunamis, storm surges or waves, is one of them. Some high resolution DEMs are being generated for multiple coast configurations (gulf, embayment, strait, estuary, harbor approaches, low-lying areas…) along French Atlantic and Channel coasts. This work is undertaken within the framework of the TANDEM project (Tsunamis in the Atlantic and the English ChaNnel: Definition of the Effects through numerical Modeling) (2014-2017). DEMs boundaries were defined considering the vicinity of French civil nuclear facilities, site effects considerations and potential tsunamigenic sources. Those were identified from available historical observations. Seamless integrated topographic and bathymetric coastal DEMs will be used by institutions taking part in the study to simulate expected wave height at regional and local scale on the French coasts, for a set of defined scenarii. The main tasks were (1) the development of a new capacity of production of DEM, (2) aiming at the release of high resolution and precision digital field models referred to vertical reference frameworks, that require (3) horizontal and vertical datum conversions (all source elevation data need to be transformed to a common datum), on the basis of (4) the building of (national and/or local) conversion grids of datum relationships based on known measurements. Challenges in coastal DEMs development deal with good practices throughout model development that can help minimizing uncertainties. This is particularly true as scattered elevation data with variable density, from multiple sources (national hydrographic services, state and local government agencies, research organizations and private engineering companies) and from many different types (paper fieldsheets to be digitized, single beam echo sounder, multibeam sonar, airborne laser

Bathymetric preference of four major genera of rectilinear benthic foraminifera within oxygen minimum zone in Arabian Sea off central west coast of India.

Digital Repository Service at National Institute of Oceanography (India)

Mazumder, A.; Nigam, R.

species, including two species of Bolivina and a single species of Uvigerina, with the bathymetrical variation from the northern Gulf of Mexico. But there is no attempt to correlate the total population of any important genus of rectilinear foraminifera...–900. Malakoff D 1998 Death by suffocation in the Gulf of Mexico; Science 281 190–192. Mallon J, Glock N and Scho¨nfeld J 2012 The response of benthic foraminifera to low-oxygen conditions of the Peruvian oxygen minimum zone; In: ANOXIA: Evidence for eukaryote...

Innovative R.E.A. tools for integrated bathymetric survey

Science.gov (United States)

Demarte, Maurizio; Ivaldi, Roberta; Sinapi, Luigi; Bruzzone, Gabriele; Caccia, Massimo; Odetti, Angelo; Fontanelli, Giacomo; Masini, Andrea; Simeone, Emilio

2017-04-01

sensors useful for seabed analysis. The very stable platform located on the top of the USV allows for taking-off and landing of the RPAS. By exploiting its higher power autonomy and load capability, the USV will be used as a mothership for the RPAS. In particular, during the missions the USV will be able to furnish recharging possibility for the RPAS and it will be able to function as a bridge for the communication between the RPAS and its control station. The main advantage of the system is the remote acquisition of high-resolution bathymetric data from RPAS in areas where the possibility to have a systematic and traditional survey are few or none. These tools (USV carrying an RPAS with Hyperspectral camera) constitute an innovative and powerful system that gives to the Emergency Response Unit the right instruments to react quickly. The developing of this support could be solve the classical conflict between resolution, needed to capture the fine scale variability and coverage, needed for the large environmental phenomena, with very high variability over a wide range of spatial and temporal scales as the coastal environment.

Optimizing the Management of High-Risk, Localized Prostate Cancer

OpenAIRE

Sundi, Debasish; Jeong, Byong Chang; Lee, Seung Bae; Han, Misop

2012-01-01

Prostate cancer has a high prevalence and a rising incidence in many parts of the world. Although many screen-detected prostate cancers may be indolent, prostate cancer remains a major contributor to mortality in men. Therefore, the appropriate diagnosis and treatment of localized prostate cancer with lethal potential are of great importance. High-risk, localized prostate cancer has multiple definitions. Treatment options that should be individualized to each patient include observation, radi...

Bathymetric and sediment facies maps for China Bend and Marcus Flats, Franklin D. Roosevelt Lake, Washington, 2008 and 2009

Science.gov (United States)

Weakland, Rhonda J.; Fosness, Ryan L.; Williams, Marshall L.; Barton, Gary J.

2011-01-01

The U.S. Geological Survey (USGS) created bathymetric and sediment facies maps for portions of two reaches of Lake Roosevelt in support of an interdisciplinary study of white sturgeon (Acipenser transmontanus) and their habitat areas within Franklin D. Roosevelt Lake, Washington. In October 2008, scientists from the USGS used a boat-mounted multibeam echo sounder (MBES) to describe bathymetric data to characterize surface relief at China Bend and Marcus Flats, between Northport and Kettle Falls, Washington. In March 2009, an underwater video camera was used to view and record sediment facies that were then characterized by sediment type, grain size, and areas of sand deposition. Smelter slag has been identified as having the characteristics of sand-sized black particles; the two non-invasive surveys attempted to identify areas containing black-colored particulate matter that may be elements and minerals, organic material, or slag. The white sturgeon population in Lake Roosevelt is threatened by the failure of natural recruitment, resulting in a native population that consists primarily of aging fish and that is gradually declining as fish die and are not replaced by nonhatchery reared juvenile fish. These fish spawn and rear in the riverine and upper reservoir reaches where smelter slag is present in the sediment of the river lake bed. Effects of slag on the white sturgeon population in Lake Roosevelt are largely unknown. Two recent studies demonstrated that copper and other metals are mobilized from slag in aqueous environments with concentrations of copper and zinc in bed sediments reaching levels of 10,000 and 30,000 mg/kg due to the presence of smelter slag. Copper was found to be highly toxic to 30-day-old white sturgeon with 96-h LC50 concentrations ranging from 3 to 5 (u or mu)g copper per liter. Older juvenile and adult sturgeons commonly ingest substantial amounts of sediment while foraging. Future study efforts in Lake Roosevelt should include sampling of

Local buckling failure analysis of high-strength pipelines

Institute of Scientific and Technical Information of China (English)

Yan Li; Jian Shuai; Zhong-Li Jin; Ya-Tong Zhao; Kui Xu

2017-01-01

Pipelines in geological disaster regions typically suffer the risk of local buckling failure because of slender structure and complex load.This paper is meant to reveal the local buckling behavior of buried pipelines with a large diameter and high strength,which are under different conditions,including pure bending and bending combined with internal pressure.Finite element analysis was built according to previous data to study local buckling behavior of pressurized and unpressurized pipes under bending conditions and their differences in local buckling failure modes.In parametric analysis,a series of parameters,including pipe geometrical dimension,pipe material properties and internal pressure,were selected to study their influences on the critical bending moment,critical compressive stress and critical compressive strain of pipes.Especially the hardening exponent of pipe material was introduced to the parameter analysis by using the Ramberg-Osgood constitutive model.Results showed that geometrical dimensions,material and internal pressure can exert similar effects on the critical bending moment and critical compressive stress,which have different,even reverse effects on the critical compressive strain.Based on these analyses,more accurate design models of critical bending moment and critical compressive stress have been proposed for high-strength pipelines under bending conditions,which provide theoretical methods for highstrength pipeline engineering.

Bathymetric mapping of submarine sand waves using multiangle sun glitter imagery: a case of the Taiwan Banks with ASTER stereo imagery

Science.gov (United States)

Zhang, Hua-guo; Yang, Kang; Lou, Xiu-lin; Li, Dong-ling; Shi, Ai-qin; Fu, Bin

2015-01-01

Submarine sand waves are visible in optical sun glitter remote sensing images and multiangle observations can provide valuable information. We present a method for bathymetric mapping of submarine sand waves using multiangle sun glitter information from Advanced Spaceborne Thermal Emission and Reflection Radiometer stereo imagery. Based on a multiangle image geometry model and a sun glitter radiance transfer model, sea surface roughness is derived using multiangle sun glitter images. These results are then used for water depth inversions based on the Alpers-Hennings model, supported by a few true depth data points (sounding data). Case study results show that the inversion and true depths match well, with high-correlation coefficients and root-mean-square errors from 1.45 to 2.46 m, and relative errors from 5.48% to 8.12%. The proposed method has some advantages over previous methods in that it requires fewer true depth data points, it does not require environmental parameters or knowledge of sand-wave morphology, and it is relatively simple to operate. On this basis, we conclude that this method is effective in mapping submarine sand waves and we anticipate that it will also be applicable to other similar topography types.

Groundwater fluxes in a shallow seasonal wetland pond: The effect of bathymetric uncertainty on predicted water and solute balances

Science.gov (United States)

Trigg, Mark A.; Cook, Peter G.; Brunner, Philip

2014-09-01

The successful management of groundwater dependent shallow seasonal wetlands requires a sound understanding of groundwater fluxes. However, such fluxes are hard to quantify. Water volume and solute mass balance models can be used in order to derive an estimate of groundwater fluxes within such systems. This approach is particularly attractive, as it can be undertaken using measurable environmental variables, such as; rainfall, evaporation, pond level and salinity. Groundwater fluxes estimated from such an approach are subject to uncertainty in the measured variables as well as in the process representation and in parameters within the model. However, the shallow nature of seasonal wetland ponds means water volume and surface area can change rapidly and non-linearly with depth, requiring an accurate representation of the wetland pond bathymetry. Unfortunately, detailed bathymetry is rarely available and simplifying assumptions regarding the bathymetry have to be made. However, the implications of these assumptions are typically not quantified. We systematically quantify the uncertainty implications for eight different representations of wetland bathymetry for a shallow seasonal wetland pond in South Australia. The predictive uncertainty estimation methods provided in the Model-Independent Parameter Estimation and Uncertainty Analysis software (PEST) are used to quantify the effect of bathymetric uncertainty on the modelled fluxes. We demonstrate that bathymetry can be successfully represented within the model in a simple parametric form using a cubic Bézier curve, allowing an assessment of bathymetric uncertainty due to measurement error and survey detail on the derived groundwater fluxes compared with the fixed bathymetry models. Findings show that different bathymetry conceptualisations can result in very different mass balance components and hence process conceptualisations, despite equally good fits to observed data, potentially leading to poor management

The local structure of high-temperature superconductors

International Nuclear Information System (INIS)

Mustre de Leon, J.; Conradson, S.D.; Bishop, A.R.; Raistrick, I.D.

1992-01-01

We show how x-ray absorption fine structure (XAFS) has been successfully used in the determination of the local crystal structure of high-temperature superconductors, with advantages over traditional diffraction techniques. We review the experimental results that yielded the first evidence for an axial-oxygen-centered lattice instability connected with the superconductivity transition. The interpretation of this instability in terms of a dynamical tunneling model suggests the presence of polarons in these materials. XAFS on Tl 2 Ba 2 CuO 6 and other Tl-based superconductors indicate the presence of local instabilities in the CuO 2 planes of these materials, in addition to axial-oxygen instabilities

High-efficiency one-dimensional atom localization via two parallel standing-wave fields

International Nuclear Information System (INIS)

Wang, Zhiping; Wu, Xuqiang; Lu, Liang; Yu, Benli

2014-01-01

We present a new scheme of high-efficiency one-dimensional (1D) atom localization via measurement of upper state population or the probe absorption in a four-level N-type atomic system. By applying two classical standing-wave fields, the localization peak position and number, as well as the conditional position probability, can be easily controlled by the system parameters, and the sub-half-wavelength atom localization is also observed. More importantly, there is 100% detecting probability of the atom in the subwavelength domain when the corresponding conditions are satisfied. The proposed scheme may open up a promising way to achieve high-precision and high-efficiency 1D atom localization. (paper)

High order scheme for the non-local transport in ICF plasmas

Energy Technology Data Exchange (ETDEWEB)

Feugeas, J.L.; Nicolai, Ph.; Schurtz, G. [Bordeaux-1 Univ., Centre Lasers Intenses et Applications (UMR 5107), 33 - Talence (France); Charrier, P.; Ahusborde, E. [Bordeaux-1 Univ., MAB, 33 - Talence (France)

2006-06-15

A high order practical scheme for a model of non-local transport is here proposed to be used in multidimensional radiation hydrodynamic codes. A high order scheme is necessary to solve non-local problems on strongly deformed meshes that are on hot point or ablation front zones. It is shown that the errors made by a classical 5 point scheme on a disturbed grid can be of the same order of magnitude as the non-local effects. The use of a 9 point scheme in a simulation of inertial confinement fusion appears to be essential.

Localized bending fatigue behavior of high-strength steel monostrands

DEFF Research Database (Denmark)

Winkler, Jan; Fischer, Gregor; Georgakis, Christos T.

2012-01-01

In this paper, the localized bending fatigue behavior of pretensioned high strength steel monostrands is investigated. Furthermore, a new methodology using an optical photogrammetry system, which can quantify surface deformations on the strand is presented. The system allows measurement of the st......In this paper, the localized bending fatigue behavior of pretensioned high strength steel monostrands is investigated. Furthermore, a new methodology using an optical photogrammetry system, which can quantify surface deformations on the strand is presented. The system allows measurement...... displacement (opening/closing and sliding) of the helically wound wires. Moreover, the results are a step towards understanding the bending fatigue damage mechanisms of monostrand cables....

Radical prostatectomy in clinically localized high-risk prostate cancer

DEFF Research Database (Denmark)

Røder, Martin Andreas; Berg, Kasper Drimer; Christensen, Ib Jarle

2013-01-01

) is regarded as primary therapy by others. This study examined the outcome for high-risk localized PCa patients treated with RP. Material and methods. Of 1300 patients who underwent RP, 231 were identified as high-risk. Patients were followed for biochemical recurrence (BCR) (defined as prostate-specific......Abstract Objective. The optimal therapeutic strategy for high-risk localized prostate cancer (PCa) is controversial. Supported by randomized trials, the combination of external beam radiation therapy (EBRT) and endocrine therapy (ET) is advocated by many, while radical prostatectomy (RP...... antigen ≥ 0.2 ng/ml), metastatic disease and survival. Excluding node-positive patients, none of the patients received adjuvant therapy before BCR was confirmed. Univariate and multivariate analysis was performed with Kaplan-Meier and Cox proportional hazard models. Results. Median follow-up was 4.4 years...

On locally uniformly linearizable high breakdown location and scale functionals

NARCIS (Netherlands)

Davies, P.L.

1998-01-01

This article gives two constructions of a weighted mean which has a large domain, is affinely equivariant, has a locally high breakdown point and is locally uniformly linearizable. One construction is based on $M$-functionals with smooth defining $\\psi$- and $\\chi$ -functions which are used to

Local high precision 3D measurement based on line laser measuring instrument

Science.gov (United States)

Zhang, Renwei; Liu, Wei; Lu, Yongkang; Zhang, Yang; Ma, Jianwei; Jia, Zhenyuan

2018-03-01

In order to realize the precision machining and assembly of the parts, the geometrical dimensions of the surface of the local assembly surfaces need to be strictly guaranteed. In this paper, a local high-precision three-dimensional measurement method based on line laser measuring instrument is proposed to achieve a high degree of accuracy of the three-dimensional reconstruction of the surface. Aiming at the problem of two-dimensional line laser measuring instrument which lacks one-dimensional high-precision information, a local three-dimensional profile measuring system based on an accurate single-axis controller is proposed. First of all, a three-dimensional data compensation method based on spatial multi-angle line laser measuring instrument is proposed to achieve the high-precision measurement of the default axis. Through the pretreatment of the 3D point cloud information, the measurement points can be restored accurately. Finally, the target spherical surface is needed to make local three-dimensional scanning measurements for accuracy verification. The experimental results show that this scheme can get the local three-dimensional information of the target quickly and accurately, and achieves the purpose of gaining the information and compensating the error for laser scanner information, and improves the local measurement accuracy.

Arc arrays: studies of high resolution techniques for multibeam bathymetric applications

Digital Repository Service at National Institute of Oceanography (India)

Chakraborty, B.; Schenke, H.W.

. This geometry is tested using the Bartlett method for varying arc and linear arrays of 30 - elements. We also examine `high resolution techniques' such as the Maximum LIkelihood (ML) method and the Maximum Entropy (ME) methods (different orders), for 16-element...

Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma

International Nuclear Information System (INIS)

Casey, Dana L.; Kushner, Brian H.; Cheung, Nai-Kong V.; Modak, Shakeel; LaQuaglia, Michael P.; Wolden, Suzanne L.

2016-01-01

Purpose: To evaluate local control after 21-Gy radiation therapy (RT) to the primary site in patients with high-risk neuroblastoma. Methods and Materials: After receiving dose-intensive chemotherapy and gross total resection (GTR), 246 patients (aged 1.2-17.9 years, median 4.0 years) with high-risk neuroblastoma underwent RT to the primary site at Memorial Sloan Kettering from 2000 to 2014. Radiation therapy consisted of 21 Gy in twice-daily fractions of 1.5 Gy each. Local failure (LF) was correlated with biologic prognostic factors and clinical findings at the time of diagnosis and start of RT. Results: Median follow-up of surviving patients was 6.4 years. Cumulative incidence of LF was 7.1% at 2 years after RT and 9.8% at 5 years after RT. The isolated LF rate was 3.0%. Eighty-six percent of all local failures were within the RT field. Local control was worse in patients who required more than 1 surgical resection to achieve GTR (22.4% vs 8.3%, P=.01). There was also a trend toward inferior local control with MYCN-amplified tumors or serum lactate dehydrogenase ≥1500 U/L (P=.09 and P=.06, respectively). Conclusion: After intensive chemotherapy and maximal surgical debulking, hyperfractionated RT with 21 Gy in high-risk neuroblastoma results in excellent local control. Given the young patient age, concern for late effects, and local control >90%, dose reduction may be appropriate for patients without MYCN amplification who achieve GTR.

Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma

Energy Technology Data Exchange (ETDEWEB)

Casey, Dana L. [Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York (United States); Kushner, Brian H.; Cheung, Nai-Kong V.; Modak, Shakeel [Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York (United States); LaQuaglia, Michael P. [Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York (United States); Wolden, Suzanne L., E-mail: woldens@mskcc.org [Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York (United States)

2016-10-01

Purpose: To evaluate local control after 21-Gy radiation therapy (RT) to the primary site in patients with high-risk neuroblastoma. Methods and Materials: After receiving dose-intensive chemotherapy and gross total resection (GTR), 246 patients (aged 1.2-17.9 years, median 4.0 years) with high-risk neuroblastoma underwent RT to the primary site at Memorial Sloan Kettering from 2000 to 2014. Radiation therapy consisted of 21 Gy in twice-daily fractions of 1.5 Gy each. Local failure (LF) was correlated with biologic prognostic factors and clinical findings at the time of diagnosis and start of RT. Results: Median follow-up of surviving patients was 6.4 years. Cumulative incidence of LF was 7.1% at 2 years after RT and 9.8% at 5 years after RT. The isolated LF rate was 3.0%. Eighty-six percent of all local failures were within the RT field. Local control was worse in patients who required more than 1 surgical resection to achieve GTR (22.4% vs 8.3%, P=.01). There was also a trend toward inferior local control with MYCN-amplified tumors or serum lactate dehydrogenase ≥1500 U/L (P=.09 and P=.06, respectively). Conclusion: After intensive chemotherapy and maximal surgical debulking, hyperfractionated RT with 21 Gy in high-risk neuroblastoma results in excellent local control. Given the young patient age, concern for late effects, and local control >90%, dose reduction may be appropriate for patients without MYCN amplification who achieve GTR.

EVALUATION OF A NOVEL UAV-BORNE TOPO-BATHYMETRIC LASER PROFILER

Directory of Open Access Journals (Sweden)

G. Mandlburger

2016-06-01

Full Text Available We present a novel topo-bathymetric laser profiler. The sensor system (RIEGL BathyCopter comprises a laser range finder, an Inertial Measurement Unit (IMU, a Global Navigation Satellite System (GNSS receiver, a control unit, and digital cameras mounted on an octocopter UAV (RiCOPTER. The range finder operates on the time-of-flight measurement principle and utilizes very short laser pulses (<1 ns in the green domain of the spectrum (λ=532 nm for measuring distances to both the water surface and the river bottom. For assessing the precision and accuracy of the system an experiment was carried out in October 2015 at a pre-alpine river (Pielach in Lower Austria. A 200 m longitudinal section and 12 river cross sections were measured with the BathyCopter sensor system at a flight altitude of 15-20 m above ground level and a measurement rate of 4 kHz. The 3D laser profiler points were compared with independent, quasi-simultaneous data acquisitions using (i the RIEGL VUX1-UAV lightweight topographic laser scanning system (bare earth, water surface and (ii terrestrial survey (river bed. Over bare earth the laser profiler heights have a std. dev. of 3 cm, the water surface height appears to be underestimated by 5 cm, and river bottom heights differ from the reference measurements by 10 cm with a std. dev. of 13 cm. When restricting the comparison to laser profiler bottom points and reference measurements with a lateral offset below 1 m, the values improve to 4 cm bias with a std. dev. of 6 cm. We report additionally on challenges in comparing UAV-borne to terrestrial profiles. Based on the accuracy and the small footprint (3.5 cm at the water surface we concluded that the acquired 3D points can potentially serve as input data (river bed geometry, grain roughness and validation data (water surface, water depth for hydrodynamic-numerical models.

Forbidden lines of highly ionized ions for localized plasma diagnostics

International Nuclear Information System (INIS)

Hinnov, E.; Fonck, R.; Suckewer, S.

1980-06-01

Numerous optically forbidden lines resulting from magnetic dipole transitions in low-lying electron configurations of highly ionized Fe, Ti and Cr atoms have been identified in PLT and PDX tokamak discharges, and applied for localized diagnostics in the high-temperature (0.5 to 3.0 keV) interior of these plasmas. The measurements include determination of local ion densities and their variation in time, and of ion motions (ion temperature, plasma rotations) through Doppler effect of the lines. These forbidden lines are particularly appropriate for such measurements because under typical tokamak conditions their emissivities are quite high (10 11 to 10 14 photons/cm 3 -sec), and their relatively long wavelengths allow the use of intricate optical techniques and instrumentation. The spatial location of the emissivity is directly measurable, and tends to occur near radii where the ionization potential of the ion in question is equal to the local electron temperature. In future larger and presumably higher-temperature tokamaks analogous measurements with somewhat heavier atoms, particularly krypton, and perhaps zirconium appear both feasible and desirable

High Power Room Temperature Terahertz Local Oscillator, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — We propose to build a high-power, room temperature compact continuous wave terahertz local oscillator for driving heterodyne receivers in the 1-5 THz frequency...

Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: Its utility for local siRNA delivery.

Science.gov (United States)

Xu, Leyuan; Yeudall, W Andrew; Yang, Hu

2017-07-15

The utility of folic acid (FA)-decorated polyamidoamine dendrimer G4 (G4-FA) as a vector was investigated for local delivery of siRNA. In a xenograft HN12 (or HN12-YFP) tumor mouse model of head and neck squamous cell carcinomas (HNSCC), intratumorally (i.t.) injected G4-FA exhibited high tumor uptake and sustained highly localized retention in the tumors according to near infrared (NIR) imaging assessment. siRNA against vascular endothelial growth factor A (siVEGFA) was chosen as a therapeutic modality. Compared to the nontherapeutic treatment groups (PBS solution or dendrimer complexed with nontherapeutic siRNA against green fluorescent protein (siGFP)), G4-FA/siVEGFA showed tumor inhibition effects in single-dose and two-dose regimen studies. In particular, two doses of G4-FA/siVEGFA i.t. administered eight days apart resulted in a more profound inhibition of tumor growth, accompanied with significant reduction in angiogenesis, as judged by CD31 staining and microvessel counts. Tumor size reduction in the two-dose regimen study was ascertained semi-quantitatively by live fluorescence imaging of YFP tumors and independently supported antitumor effects of G4-FA/siVEGFA. Taken together, G4-FA shows high tumor uptake and sustained retention properties, making it a suitable platform for local delivery of siRNAs to treat cancers that are readily accessible such as HNSCC. Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and is difficult to transfect for gene therapy. We developed folate receptor (FR)-targeted polyamidoamine (PAMAM) dendrimer for enhanced delivery of genes to HNSCC and gained in-depth understanding of how gene delivery and transfection in head and neck squamous cancer cells can be enhanced via FR-targeted PAMAM dendrimers. The results we report here are encouraging and present latest advances in using dendrimers for cancer therapies, in particular for HNSCC. Our work has demonstrated that localized delivery of FR

Condensate localization by mesoscale disorder in high-Tc superconductors

International Nuclear Information System (INIS)

Kumar, N.

1994-06-01

We propose and solve approximately a phenomenological model for Anderson localization of the macroscopic wavefunction for an inhomogeneous superconductor quench-disordered on the mesoscale of the order of the coherence length ξ 0 . Our treatment is based on the non-linear Schroedinger equation resulting from the Ginzburg-Landau free-energy functional having a spatially random coefficient representing spatial disorder of the pairing interaction. Linearization of the equation, valid close to the critical temperature T c , or to the upper critical field H c2 (T c ) maps it to the Anderson localization problem with T c identified with the mobility edge. For the highly anisotropic high-T c materials and thin (2D) films in the quantum Hall geometry, we predict windows of re-entrant superconductivity centered at integrally spaced temperature values. Our model treatment also provides a possible explanation for the critical current J c perpendicular becoming non-zero on cooling before J c parallel does in some high-T c superconductors. (author). 18 refs

High-resolution seismic wave propagation using local time stepping

KAUST Repository

Peter, Daniel

2017-03-13

High-resolution seismic wave simulations often require local refinements in numerical meshes to accurately capture e.g. steep topography or complex fault geometry. Together with explicit time schemes, this dramatically reduces the global time step size for ground-motion simulations due to numerical stability conditions. To alleviate this problem, local time stepping (LTS) algorithms allow an explicit time stepping scheme to adapt the time step to the element size, allowing nearoptimal time steps everywhere in the mesh. This can potentially lead to significantly faster simulation runtimes.

High-resolution seismic wave propagation using local time stepping

KAUST Repository

Peter, Daniel; Rietmann, Max; Galvez, Percy; Ampuero, Jean Paul

2017-01-01

High-resolution seismic wave simulations often require local refinements in numerical meshes to accurately capture e.g. steep topography or complex fault geometry. Together with explicit time schemes, this dramatically reduces the global time step

Genome architecture enables local adaptation of Atlantic cod despite high connectivity

DEFF Research Database (Denmark)

Barth, Julia M I; Berg, Paul R; Jonsson, Per R.

2017-01-01

Adaptation to local conditions is a fundamental process in evolution; however, mechanisms maintaining local adaptation despite high gene flow are still poorly understood. Marine ecosystems provide a wide array of diverse habitats that frequently promote ecological adaptation even in species...... characterized by strong levels of gene flow. As one example, populations of the marine fish Atlantic cod (Gadus morhua) are highly connected due to immense dispersal capabilities but nevertheless show local adaptation in several key traits. By combining population genomic analyses based on 12K single......-nucleotide polymorphisms with larval dispersal patterns inferred using a biophysical ocean model, we show that Atlantic cod individuals residing in sheltered estuarine habitats of Scandinavian fjords mainly belong to offshore oceanic populations with considerable connectivity between these diverse ecosystems. Nevertheless...

High-frequency asymptotics of the local vertex function. Algorithmic implementations

Energy Technology Data Exchange (ETDEWEB)

Tagliavini, Agnese; Wentzell, Nils [Institut fuer Theoretische Physik, Eberhard Karls Universitaet, 72076 Tuebingen (Germany); Institute for Solid State Physics, Vienna University of Technology, 1040 Vienna (Austria); Li, Gang; Rohringer, Georg; Held, Karsten; Toschi, Alessandro [Institute for Solid State Physics, Vienna University of Technology, 1040 Vienna (Austria); Taranto, Ciro [Institute for Solid State Physics, Vienna University of Technology, 1040 Vienna (Austria); Max Planck Institute for Solid State Research, D-70569 Stuttgart (Germany); Andergassen, Sabine [Institut fuer Theoretische Physik, Eberhard Karls Universitaet, 72076 Tuebingen (Germany)

2016-07-01

Local vertex functions are a crucial ingredient of several forefront many-body algorithms in condensed matter physics. However, the full treatment of their frequency dependence poses a huge limitation to the numerical performance. A significant advancement requires an efficient treatment of the high-frequency asymptotic behavior of the vertex functions. We here provide a detailed diagrammatic analysis of the high-frequency asymptotic structures and their physical interpretation. Based on these insights, we propose a frequency parametrization, which captures the whole high-frequency asymptotics for arbitrary values of the local Coulomb interaction and electronic density. We present its algorithmic implementation in many-body solvers based on parquet-equations as well as functional renormalization group schemes and assess its validity by comparing our results for the single impurity Anderson model with exact diagonalization calculations.

High-precision two-dimensional atom localization via quantum interference in a tripod-type system

International Nuclear Information System (INIS)

Wang, Zhiping; Yu, Benli

2014-01-01

A scheme is proposed for high-precision two-dimensional atom localization in a four-level tripod-type atomic system via measurement of the excited state population. It is found that because of the position-dependent atom–field interaction, the precision of 2D atom localization can be significantly improved by appropriately adjusting the system parameters. Our scheme may be helpful in laser cooling or atom nanolithography via high-precision and high-resolution atom localization. (letter)

Localities With Elevated Radiation Background in the High Karst Zone of Montenegro

International Nuclear Information System (INIS)

Vukotic, P.; Svrkota, R.; Andjelic, T.; Zekic, R.; Antovic, N.

2011-01-01

Research aimed to find localities in Montenegro with an elevated terrestrial gamma background was conducted during the period 2008-2009. For this purpose, 138 localities which have geological formations known to contain minerals with potentially high concentrations of U, Th and K, were selected throughout the country for a dosimetric survey. There are four distinctive geotectonic units in Montenegro: the Adriatic-Ionian Zone (JZ), the Budva-Cukali Zone (BZ), the High Karst Zone (VK), and the Durmitor Tectonic Unit (DTJ). The central and southern parts of Montenegro belong to the VK zone, whose geological structure is predominated by Mesozoic carbonate sediments, with occurrences of red and white bauxite formations, Triassic volcanic rocks, Paleogene flysch sediments and Quaternary sediments. In total, 38 localities belonging to the VK zone were selected for field investigations of terrestrial radiation. Knowing from earlier investigations that in Montenegro the average absorbed dose-rate in the air, 1 m above the ground, is 55 nGy/h, it was arbitrarily adopted that only localities with absorbed doses at least 50 % above this average value would be considered as having a relatively elevated radiation background. Field measurements have shown that 12 of the surveyed localities in the VK zone have such elevated dose values, five of them being with the highest dose rates in Montenegro. Among these five sites, the highest dose rate (192 nGy/h) was found at a locality which lies on andesite volcanic rock, while the other four localities (131 - 149 nGy/h) lie on bauxite deposits. Compared to the other areas in the world known to have a high natural radiation background, all of these localities in Montenegro have a moderately elevated radiation level. From the 12 localities with a relatively elevated radiation background, soil samples have been collected and analyzed by gamma spectrometry to determine activity concentrations of 40K, 232Th, 235U, 238U, 226Ra and 137Cs

Simulation of a Local Collision of SC Wall Using High Energy Absorbing Steel

Energy Technology Data Exchange (ETDEWEB)

Yoo, H. K.; Chung, C. H.; Park, J.; Lee, J. W. [Dankook University, Yongin (Korea, Republic of); Kim, S. Y. [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

2011-05-15

Local damage evaluations for nuclear power plant(NPP) design are performed against turbine impact, tornado impact, airplane engine impact, etc., where turbine is a internal source of impact, whereas tornado and airplane engine are external sources of impact. The thickness of NPP wall structure is determined at initial design stage not to be penetrated by local impacts. This study investigated the local damage of NPP substructure against internal turbine impact. Simulation of local collisions of SC wall in NPP structure, which consists of two models: one using general steel and the other using high energy absorbing steel, were performed. The performance of SC wall using ductile high energy absorbing steel can be greatly improved on local collisions when compared with that of general steel

Simulation of a Local Collision of SC Wall Using High Energy Absorbing Steel

International Nuclear Information System (INIS)

Yoo, H. K.; Chung, C. H.; Park, J.; Lee, J. W.; Kim, S. Y.

2011-01-01

Local damage evaluations for nuclear power plant(NPP) design are performed against turbine impact, tornado impact, airplane engine impact, etc., where turbine is a internal source of impact, whereas tornado and airplane engine are external sources of impact. The thickness of NPP wall structure is determined at initial design stage not to be penetrated by local impacts. This study investigated the local damage of NPP substructure against internal turbine impact. Simulation of local collisions of SC wall in NPP structure, which consists of two models: one using general steel and the other using high energy absorbing steel, were performed. The performance of SC wall using ductile high energy absorbing steel can be greatly improved on local collisions when compared with that of general steel

High-dimensional atom localization via spontaneously generated coherence in a microwave-driven atomic system.

Science.gov (United States)

Wang, Zhiping; Chen, Jinyu; Yu, Benli

2017-02-20

We investigate the two-dimensional (2D) and three-dimensional (3D) atom localization behaviors via spontaneously generated coherence in a microwave-driven four-level atomic system. Owing to the space-dependent atom-field interaction, it is found that the detecting probability and precision of 2D and 3D atom localization behaviors can be significantly improved via adjusting the system parameters, the phase, amplitude, and initial population distribution. Interestingly, the atom can be localized in volumes that are substantially smaller than a cubic optical wavelength. Our scheme opens a promising way to achieve high-precision and high-efficiency atom localization, which provides some potential applications in high-dimensional atom nanolithography.

Selection of local extremophile lactic acid bacteria with high capacity ...

African Journals Online (AJOL)

This study is related to the isolation and identification of strains of local thermophilic lactic acid bacteria belonging to the species, Streptococcus thermophilus and Lactobacillus bulgaricus. These bacteria can exist under extreme conditions of the digestive tract (acidity and high concentration of bile salts) and have a high ...

Salvage high-dose-rate brachytherapy for local prostate cancer recurrence after radical radiotherapy

Directory of Open Access Journals (Sweden)

V. A. Solodkiy

2016-01-01

Full Text Available Studies salvage interstitial radiation therapy for recurrent prostate cancer, launched at the end of the XX century. In recent years, more and more attention is paid to high-dose-rate brachytherapy (HDR-BT as a method of treating local recurrence.The purpose of research – preliminary clinical results of salvage high-dose-rate brachytherapy applied in cases of suspected local recurrence or of residual tumour after radiotherapy.Preliminary findings indicate the possibility of using HDR-BT, achieving local tumor control with low genitourinary toxicity.

Local-metrics error-based Shepard interpolation as surrogate for highly non-linear material models in high dimensions

Science.gov (United States)

Lorenzi, Juan M.; Stecher, Thomas; Reuter, Karsten; Matera, Sebastian

2017-10-01

Many problems in computational materials science and chemistry require the evaluation of expensive functions with locally rapid changes, such as the turn-over frequency of first principles kinetic Monte Carlo models for heterogeneous catalysis. Because of the high computational cost, it is often desirable to replace the original with a surrogate model, e.g., for use in coupled multiscale simulations. The construction of surrogates becomes particularly challenging in high-dimensions. Here, we present a novel version of the modified Shepard interpolation method which can overcome the curse of dimensionality for such functions to give faithful reconstructions even from very modest numbers of function evaluations. The introduction of local metrics allows us to take advantage of the fact that, on a local scale, rapid variation often occurs only across a small number of directions. Furthermore, we use local error estimates to weigh different local approximations, which helps avoid artificial oscillations. Finally, we test our approach on a number of challenging analytic functions as well as a realistic kinetic Monte Carlo model. Our method not only outperforms existing isotropic metric Shepard methods but also state-of-the-art Gaussian process regression.

Predicting the aquatic stage sustainability of a restored backwater channel combining in-situ and airborne remotely sensed bathymetric models.

Science.gov (United States)

Jérôme, Lejot; Jérémie, Riquier; Hervé, Piégay

2014-05-01

is high, primarily driven by fine sediment accumulation and decrease exponentially through time (e.g. median rate of 12 cm.an-1 two years after restoration and of 6 cm.an-1 nine year after restoration). Predicted water depth from field measures are rather good (R²= 0.85; RMSE = 10.7) as well as Airborne bathymetric models (R² values between 0.71 and 0.89 ; vertical error between 9 and 12 cm). Predictive models demonstrate that such restoration of forms can be a sustainable measure along the Rhône river. More widely, these results can help managers in the definition of adaptive measures or can be used to improve the design of restoration plan.

Environmental and bathymetric influences on abyssal bait-attending communities of the Clarion Clipperton Zone

Science.gov (United States)

Leitner, Astrid B.; Neuheimer, Anna B.; Donlon, Erica; Smith, Craig R.; Drazen, Jeffrey C.

2017-07-01

The Clarion-Clipperton Zone (CCZ) is one of the richest manganese nodule provinces in the world and has recently become a focus area for manganese nodule mining interests. However, this vast area remains poorly studied and highly undersampled. In this study, the abyssal bait-attending fauna is documented for the first time using a series of baited camera deployments in various locations across the CCZ. A bait-attending community intermediate between those typical of the California margin and Hawaii was found in the larger CCZ area, generally dominated by rattail fishes, dendrobranchiate shrimp, and zoarcid and ophidiid fishes. Additionally, the western and eastern ends of the CCZ had different communities, with the western region characterized by decreased dominance of rattails and small shrimps and increased dominance of ophidiids (especially Bassozetus sp. and Barathrites iris) and large shrimps. This trend may be related to increasing distance from the continental margin. We also test the hypothesis that bait-attending communities change across the CCZ in response to key environmental predictors, especially topography and nodule cover. Our analyses showed that higher nodule cover and elevated topography, as quantified using the benthic positioning index (BPI), increase bait-attending community diversity. Elevated topography generally had higher relative abundances, but taxa also showed differing responses to the BPI metric and bottom temperature, causing significant community compositional change over varying topography and temperatures. Larger individuals of the dominant scavenger in the CCZ, Coryphaenoides spp., were correlated with areas of higher nodule cover and with abyssal hills, suggesting these areas may be preferred habitat. Our results suggest that nodule cover is important to all levels of the benthic ecosystem and that nodule mining could have negative impacts on even the top-level predators and scavengers in the CCZ. Additionally, there is

High-sensitivity visualization of localized electric fields using low-energy electron beam deflection

Science.gov (United States)

Jeong, Samuel; Ito, Yoshikazu; Edwards, Gary; Fujita, Jun-ichi

2018-06-01

The visualization of localized electronic charges on nanocatalysts is expected to yield fundamental information about catalytic reaction mechanisms. We have developed a high-sensitivity detection technique for the visualization of localized charges on a catalyst and their corresponding electric field distribution, using a low-energy beam of 1 to 5 keV electrons and a high-sensitivity scanning transmission electron microscope (STEM) detector. The highest sensitivity for visualizing a localized electric field was ∼0.08 V/µm at a distance of ∼17 µm from a localized charge at 1 keV of the primary electron energy, and a weak local electric field produced by 200 electrons accumulated on the carbon nanotube (CNT) apex can be visualized. We also observed that Au nanoparticles distributed on a CNT forest tended to accumulate a certain amount of charges, about 150 electrons, at a ‑2 V bias.

Results of repeat bathymetric and velocimetric surveys at the Amelia Earhart Bridge on U.S. Highway 59 over the Missouri River at Atchison, Kansas, 2009-2013

Science.gov (United States)

Huizinga, Richard J.

2013-01-01

Bathymetric and velocimetric data were collected six times by the U.S. Geological Survey, in cooperation with the Kansas Department of Transportation, in the vicinity of Amelia Earhart Bridge on U.S. Highway 59 over the Missouri River at Atchison, Kansas. A multibeam echosounder mapping system and an acoustic Doppler current meter were used to obtain channel-bed elevations and depth-averaged velocities for a river reach approximately 2,300 feet long and extending across the active channel of the Missouri River. The bathymetric and velocimetric surveys provide a “snapshot” of the channel conditions at the time of each survey, and document changes to the channel-bed elevations and velocities during the course of construction of a new bridge for U.S. Highway 59 downstream from the Amelia Earhart Bridge. The baseline survey in June 2009 revealed substantial scour holes existed at the railroad bridge piers upstream from and at pier 10 of the Amelia Earhart Bridge, with mostly uniform flow and velocities throughout the study reach. After the construction of a trestle and cofferdam on the left (eastern) bank downstream from the Amelia Earhart Bridge, a survey on June 2, 2010, revealed scour holes with similar size and shape as the baseline for similar flow conditions, with slightly higher velocities and a more substantial contraction of flow near the bridges than the baseline. Subsequent surveys during flooding conditions in June 2010 and July 2011 revealed substantial scour near the bridges compared to the baseline survey caused by the contraction of flow; however, the larger flood in July 2011 resulted in less scour than in June 2010, partly because the removal of the cofferdam for pier 5 of the new bridge in March 2011 diminished the contraction near the bridges. Generally, the downstream part of the study reach exhibited varying amounts of scour in all of the surveys except the last when compared to the baseline. During the final survey, velocities throughout the

High-Intensity Focused Ultrasound (HIFU) in Localized Prostate Cancer Treatment

International Nuclear Information System (INIS)

Alkhorayef, Mohammed; Mahmoud, Mustafa Z.; Alzimami, Khalid S.; Sulieman, Abdelmoneim; Fagiri, Maram A.

2015-01-01

High-intensity focused ultrasound (HIFU) applies high-intensity focused ultrasound energy to locally heat and destroy diseased or damaged tissue through ablation. This study intended to review HIFU to explain the fundamentals of HIFU, evaluate the evidence concerning the role of HIFU in the treatment of prostate cancer (PC), review the technologies used to perform HIFU and the published clinical literature regarding the procedure as a primary treatment for PC. Studies addressing HIFU in localized PC were identified in a search of internet scientific databases. The analysis of outcomes was limited to journal articles written in English and published between 2000 and 2013. HIFU is a non-invasive approach that uses a precisely delivered ultrasound energy to achieve tumor cell necrosis without radiation or surgical excision. In current urological oncology, HIFU is used clinically in the treatment of PC. Clinical research on HIFU therapy for localized PC began in the 1990s, and the majority of PC patients were treated with the Ablatherm device. HIFU treatment for localized PC can be considered as an alternative minimally invasive therapeutic modality for patients who are not candidates for radical prostatectomy. Patients with lower pre-HIFU PSA level and favourable pathologic Gleason score seem to present better oncologic outcomes. Future advances in technology and safety will undoubtedly expand the HIFU role in this indication as more of patient series are published, with a longer follow-up period

Prognostic factors of inoperable localized lung cancer treated by high dose radiotherapy

International Nuclear Information System (INIS)

Schaake-Koning, C.S.; Schuster-Uitterhoeve, L.; Hart, G.; Gonzalez, D.G.

1983-01-01

A retrospective study was made of the results of high dose radiotherapy (greater than or equal to 50 Gy) given to 171 patients with inoperable, intrathoracic non small cell lung cancer from January 1971-April 1973. Local control was dependent on the total tumor dose: after one year local control was 63% for patients treated with >65 Gy, the two year local control was 35%. If treated with 2 , the one year local control was 72%; the two year local control was 44%. Local control was also influenced by the performance status, by the localization of the primary tumor in the left upper lobe and in the periphery of the lung. Local control for tumors in the left upper lobe and in the periphery of the lung was about 70% after one year, and about 40% after two years. The one and two years survival results were correlated with the factors influencing local control. The dose factor, the localization factors and the performance influenced local control independently. Tumors localized in the left upper lobe did metastasize less than tumors in the lower lobe, or in a combination of the two. This was not true for the right upper lobe. No correlation between the TNM system, pathology and the prognosis was found

Geomorphic and hydraulic controls on large-scale riverbank failure on a mixed bedrock-alluvial river system, the River Murray, South Australia: a bathymetric analysis.

Science.gov (United States)

De Carli, E.; Hubble, T.

2014-12-01

During the peak of the Millennium Drought (1997-2010) pool-levels in the lower River Murray in South Australia dropped 1.5 metres below sea level, resulting in large-scale mass failure of the alluvial banks. The largest of these failures occurred without signs of prior instability at Long Island Marina whereby a 270 metre length of populated and vegetated riverbank collapsed in a series of rotational failures. Analysis of long-reach bathymetric surveys of the river channel revealed a strong relationship between geomorphic and hydraulic controls on channel width and downstream alluvial failure. As the entrenched channel planform meanders within and encroaches upon its bedrock valley confines the channel width is 'pinched' and decreases by up to half, resulting in a deepening thalweg and channel bed incision. The authors posit that flow and shear velocities increase at these geomorphically controlled 'pinch-points' resulting in complex and variable hydraulic patterns such as erosional scour eddies, which act to scour the toe of the slope over-steepening and destabilising the alluvial margins. Analysis of bathymetric datasets between 2009 and 2014 revealed signs of active incision and erosional scour of the channel bed. This is counter to conceptual models which deem the backwater zone of a river to be one of decelerating flow and thus sediment deposition. Complex and variable flow patterns have been observed in other mixed alluvial-bedrock river systems, and signs of active incision observed in the backwater zone of the Mississippi River, United States. The incision and widening of the lower Murray River suggests the channel is in an erosional phase of channel readjustment which has implications for riverbank collapse on the alluvial margins. The prevention of seawater ingress due to barrage construction at the Murray mouth and Southern Ocean confluence, allowed pool-levels to drop significantly during the Millennium Drought reducing lateral confining support to the

Analysis of local warm forming of high strength steel using near infrared ray energy

Energy Technology Data Exchange (ETDEWEB)

Yang, W. H., E-mail: whyang21@hyundai.com [Hyundai Motor Company, 700 Yeompo-ro, Buk-Gu, Ulsan, 683-791 (Korea, Republic of); Lee, K., E-mail: klee@deform.co.kr [Solution Lab, 502, 102, Dunsan-daero 117 beon-gil, Seo-Gu, Daejeon, 302-834 (Korea, Republic of); Lee, E. H., E-mail: mtgs2@kaist.ac.kr, E-mail: dyyang@kaist.ac.kr; Yang, D. Y., E-mail: mtgs2@kaist.ac.kr, E-mail: dyyang@kaist.ac.kr [KAIST, Science Town291, Daehak-ro, Yuseong-Gu, Daejeon 305-701 (Korea, Republic of)

2013-12-16

The automotive industry has been pressed to satisfy more rigorous fuel efficiency requirements to promote energy conservation, safety features and cost containment. To satisfy this need, high strength steel has been developed and used for many different vehicle parts. The use of high strength steels, however, requires careful analysis and creativity in order to accommodate its relatively high springback behavior. An innovative method, called local warm forming with near infrared ray, has been developed to help promote the use of high strength steels in sheet metal forming. For this method, local regions of the work piece are heated using infrared ray energy, thereby promoting the reduction of springback behavior. In this research, a V-bend test is conducted with DP980. After springback, the bend angles for specimens without local heating are compared to those with local heating. Numerical analysis has been performed using the commercial program, DEFORM-2D. This analysis is carried out with the purpose of understanding how changes to the local stress distribution will affect the springback during the unloading process. The results between experimental and computational approaches are evaluated to assure the accuracy of the simulation. Subsequent numerical simulation studies are performed to explore best practices with respect to thermal boundary conditions, timing, and applicability to the production environment.

Analysis of local warm forming of high strength steel using near infrared ray energy

International Nuclear Information System (INIS)

Yang, W. H.; Lee, K.; Lee, E. H.; Yang, D. Y.

2013-01-01

The automotive industry has been pressed to satisfy more rigorous fuel efficiency requirements to promote energy conservation, safety features and cost containment. To satisfy this need, high strength steel has been developed and used for many different vehicle parts. The use of high strength steels, however, requires careful analysis and creativity in order to accommodate its relatively high springback behavior. An innovative method, called local warm forming with near infrared ray, has been developed to help promote the use of high strength steels in sheet metal forming. For this method, local regions of the work piece are heated using infrared ray energy, thereby promoting the reduction of springback behavior. In this research, a V-bend test is conducted with DP980. After springback, the bend angles for specimens without local heating are compared to those with local heating. Numerical analysis has been performed using the commercial program, DEFORM-2D. This analysis is carried out with the purpose of understanding how changes to the local stress distribution will affect the springback during the unloading process. The results between experimental and computational approaches are evaluated to assure the accuracy of the simulation. Subsequent numerical simulation studies are performed to explore best practices with respect to thermal boundary conditions, timing, and applicability to the production environment

Local transport in Joint European Tokamak edge-localized, high-confinement mode plasmas with H, D, DT, and T isotopes

International Nuclear Information System (INIS)

Budny, R. V.; Ernst, D. R.; Hahm, T. S.; McCune, D. C.; Christiansen, J. P.; Cordey, J. G.; Gowers, C. G.; Guenther, K.; Hawkes, N.; Jarvis, O. N.

2000-01-01

The edge-localized, high-confinement mode regime is of interest for future Tokamak reactors since high performance has been sustained for long durations. Experiments in the Joint European Tokamak [M. Keilhacker , Nuclear Fusion 39, 209 (1999)] have studied this regime using scans with the toroidal field and plasma current varied together in H, D, DT, and T isotopes. The local energy transport in more than fifty of these plasmas is analyzed, and empirical scaling relations are derived for energy transport coefficients during quasi-steady state conditions using dimensionless parameters. Neither the Bohm nor gyro-Bohm expressions give the shapes of the profiles. The scalings with β and ν * are in qualitative agreement with Ion Temperature Gradient theory

A high-resolution computational localization method for transcranial magnetic stimulation mapping.

Science.gov (United States)

Aonuma, Shinta; Gomez-Tames, Jose; Laakso, Ilkka; Hirata, Akimasa; Takakura, Tomokazu; Tamura, Manabu; Muragaki, Yoshihiro

2018-05-15

Transcranial magnetic stimulation (TMS) is used for the mapping of brain motor functions. The complexity of the brain deters determining the exact localization of the stimulation site using simplified methods (e.g., the region below the center of the TMS coil) or conventional computational approaches. This study aimed to present a high-precision localization method for a specific motor area by synthesizing computed non-uniform current distributions in the brain for multiple sessions of TMS. Peritumoral mapping by TMS was conducted on patients who had intra-axial brain neoplasms located within or close to the motor speech area. The electric field induced by TMS was computed using realistic head models constructed from magnetic resonance images of patients. A post-processing method was implemented to determine a TMS hotspot by combining the computed electric fields for the coil orientations and positions that delivered high motor-evoked potentials during peritumoral mapping. The method was compared to the stimulation site localized via intraoperative direct brain stimulation and navigated TMS. Four main results were obtained: 1) the dependence of the computed hotspot area on the number of peritumoral measurements was evaluated; 2) the estimated localization of the hand motor area in eight non-affected hemispheres was in good agreement with the position of a so-called "hand-knob"; 3) the estimated hotspot areas were not sensitive to variations in tissue conductivity; and 4) the hand motor areas estimated by this proposal and direct electric stimulation (DES) were in good agreement in the ipsilateral hemisphere of four glioma patients. The TMS localization method was validated by well-known positions of the "hand-knob" in brains for the non-affected hemisphere, and by a hotspot localized via DES during awake craniotomy for the tumor-containing hemisphere. Copyright © 2018 Elsevier Inc. All rights reserved.

Localized Electrochemiluminescence from Nanoneedle Electrodes for Very-high-density Electrochemical Sensing

KAUST Repository

Zhang, Jingjing

2017-09-28

In this paper, localized electrochemiluminescence (ECL) was visualized from nanoneedle electrodes that achieved very-high-density electrochemical sensing. The localized luminescence at the nanometer-sized tip observed was ascribed to enhanced mass transfer of the luminescence probe at the tip than on the planar surface surrounding the tip, which provided higher luminescence at the tip. The size of the luminescence spots was restricted to 15 μm permitting the electrochemical analysis with a density over 4 × 103 spots/mm2. The positive correlation between the luminescence intensity at the tips and the concentration of hydrogen peroxide supported the quantitative ECL analysis using nanoneedle electrodes. The further modification of glucose oxidase at the electrode surface conceptually demonstrated that the concentration of glucose ranging from 0.5 to 5 mM could be quantified using the luminescence at the tips, which could be further applied for the detection of multiple molecules in the complex biosystem. This successful localized ECL offers a specific strategy for the development of very-high-density electrochemical arrays without the complicated chip design.

Research in high speed fiber optics local area networks

Science.gov (United States)

Tobagi, F. A.

1986-01-01

The design of high speed local area networks (HSLAN) for communication among distributed devices requires solving problems in three areas: the network medium and its topology, the medium access control, and the network interface. Considerable progress was already made in the first two areas. Accomplishments are divided into two groups according to their theoretical or experimental nature. A brief summary is given.

Postoperative chemoradiotherapy in high risk locally advanced gastric cancer

Energy Technology Data Exchange (ETDEWEB)

Song, Sang Hyuk; Chie, Eui Kyu; Kim, Kyu Bo; Lee, Hyuk Joon; Yang, Han Kwang; Han, Sae Won; Oh, Do Youn; Im, Seok Ah; Bang, Yung Jue; Ha, Sung W. [Seoul National University College of Medicine, Seoul(Korea, Republic of)

2012-12-15

To evaluate treatment outcome of patients with high risk locally advanced gastric cancer after postoperative chemoradiotherapy. Between May 2003 and May 2012, thirteen patients who underwent postoperative chemoradiotherapy for gastric cancer with resection margin involvement or adjacent structure invasion were retrospectively analyzed. Concurrent chemotherapy was administered in 10 patients. Median dose of radiation was 50.4 Gy (range, 45 to 55.8 Gy). The median follow-up duration for surviving patients was 48 months (range, 5 to 108 months). The 5-year overall survival rate was 42% and the 5-year disease-free survival rate was 28%. Major pattern of failure was peritoneal seeding with 46%. Loco-regional recurrence was reported in only one patient. Grade 2 or higher gastrointestinal toxicity occurred in 54% of the patients. However, there was only one patient with higher than grade 3 toxicity. Despite reported suggested role of adjuvant radiotherapy with combination chemotherapy in gastric cancer, only very small portion of the patients underwent the treatment. Results from this study show that postoperative chemoradiotherapy provided excellent locoregional control with acceptable and manageable treatment related toxicity in patients with high risk locally advanced gastric cancer. Thus, postoperative chemoradiotherapy may improve treatment result in terms of locoregional control in these high risk patients. However, as these findings are based on small series, validation with larger cohort is suggested.

Focused fluid-flow processes through high-quality bathymetric, 2D seismic and Chirp data from the southern parts of the Bay of Biscay, France

Science.gov (United States)

Baudon, Catherine; Gillet, Hervé; Cremer, Michel

2013-04-01

High-quality bathymetric, 2D seismic and Chirp data located in the southern parts of the Bay of Biscay, France, collected by the University of Bordeaux 1 (Cruises ITSAS 2, 2001; PROSECAN 3, 2006 and SARGASS, 2010) have recently been compiled. The survey area widely covers the Capbreton Canyon, which lies on the boundary between two major structural zones: the Aquitanian passive margin to the North, and the Basque-Cantabrian margin to the South which corresponds to the offshore Pyrenean front. The dataset revealed a large number of key seafloor features potentially associated with focused fluid-flow processes and subsurface sediment-remobilization. Focused fluid migration through sub-seabed sediments is a common phenomenon on continental margins worldwide and has widespread implications from both industrial and fundamental perspectives, from seafloor marine environmental issues to petroleum exploration and hazard assessments. Our study analyses the relationships between seafloor features, deeper structures and fluid migration through the Plio-Quaternary sedimentary pile. The geometrical characteristics, mechanisms of formation and kinematics of four main groups of seabed features have been investigated. (i) A 150km2 field of pockmarks can be observed on the Basque margin. These features are cone-shaped circular or elliptical depressions that are either randomly distributed as small pockmarks (diameter < 20m) or aligned in trains of large pockmarks (ranging from 200 to 600m in diameter) along shallow troughs leading downstream to the Capbreton Canyon. Seismic data show that most pockmarks reach the seabed through vertically staked V-shaped features but some are buried and show evidence of lateral migration through time. (ii) A second field of widely-spaced groups of pockmarks pierce the upper slope of the Aquitanian margin. These depressions are typically a few hundred meters in diameter and seem to be preferentially located in the troughs or on the stoss sides of

High-resolution bathymetry as a primary exploration tool for seafloor massive sulfide deposits - lessons learned from exploration on the Mid-Atlantic and Juan de Fuca Ridges, and northern Lau Basin

Science.gov (United States)

Jamieson, J. W.; Clague, D. A.; Petersen, S.; Yeo, I. A.; Escartin, J.; Kwasnitschka, T.

2016-12-01

High-resolution, autonomous underwater vehicle (AUV)-derived multibeam bathymetry is increasingly being used as an exploration tool for delineating the size and extent of hydrothermal vent fields and associated seafloor massive sulfide deposits. However, because of the limited amount of seafloor that can be surveyed during a single dive, and the challenges associated with distinguishing hydrothermal chimneys and mounds from other volcanic and tectonic features using solely bathymetric data, AUV mapping surveys have largely been employed as a secondary exploration tool once hydrothermal sites have been discovered using other exploration methods such as plume, self-potential and TV surveys, or ROV and submersible dives. Visual ground-truthing is often required to attain an acceptable level of confidence in the hydrothermal origin of features identified in AUV-derived bathymetry. Here, we present examples of high-resolution bathymetric surveys of vent fields from a variety of tectonic environments, including slow- and intermediate-rate mid-ocean ridges, oceanic core complexes and back arc basins. Results illustrate the diversity of sulfide deposit morphologies, and the challenges associated with identifying hydrothermal features in different tectonic environments. We present a developing set of criteria that can be used to distinguish hydrothermal deposits in bathymetric data, and how AUV surveys can be used either on their own or in conjunction with other exploration techniques as a primary exploration tool.

Localized corrosion information using high resolution measurement devices

DEFF Research Database (Denmark)

Ambat, Rajan

2005-01-01

High performance demand for several engineering alloys and components, and miniaturization of electronics and development of MEMS requires better understanding of local corrosion characteristics frequently down to µm scale. This is because in metallic materials corrosion is a sensitive function...... in conjunction with microstructural analysis, using advanced microscopic tools, becomes very important. Corrosion of microelectronics circuits and MEMs is also a recent problem, which demands measurement resolution down to few microns as the components are extremely small, and measurement needs to be carried out...

Species composition and bathymetric distribution of gorgonians (Anthozoa: Octocorallia on the Southern Mexican Pacific coast

Directory of Open Access Journals (Sweden)

Rosalinda Abeytia

2013-09-01

Full Text Available Gorgonians are important components of coastal ecosystems, as they provide niches, natural compounds with medical applications and are used as bioindicators. Species composition and assemblage structure of gorgonians (Anthozoa: Octocorallia were studied along a bathymetric profile in the Southern Mexican Pacific coast. Species composition was based on specimens collected within a depth range of 0-70m in 15 sites. The relative abundance of species was determined in six sites at four depths (5, 10, 20 and 25m using three 10m2 transects at each depth level. Twenty-seven species of gorgonians belonging to six genera and three families were registered. The species composition varied with depth: 11 species were distributed between 0-25m depth, while 17 species were found between 40-70m depth interval. The shallow zone is characterized by a relatively large abundance of gorgonians, dominated by colonies of Leptogorgia cuspidata and L. ena. In contrast, the deepest zone was characterized by relatively low abundance of gorgonians, dominated by L. alba, the only species observed in both depth intervals. The similarity analysis showed differences in the composition and abundance of species by depth and site, suggesting that the main factor in determining the assemblage structure is depth. Results of this study suggest that the highest richness of gorgonian species in the study area may be located at depths of 40-70m, whereas the highest abundances are found between 5 and 10m depth. This study represents a contribution to the poorly known eastern Pacific gorgonian biota.

Local endemicity and high diversity characterise high-latitude coral- Symbiodinium partnerships

Science.gov (United States)

Wicks, L. C.; Sampayo, E.; Gardner, J. P. A.; Davy, S. K.

2010-12-01

Obligate symbiotic dinoflagellates ( Symbiodinium) residing within the tissues of most reef invertebrates are important in determining the tolerance range of their host. Coral communities living at high latitudes experience wide fluctuations in environmental conditions and thus provide an ideal system to gain insights into the range within which the symbiotic relationship can be sustained. Further, understanding whether and how symbiont communities associated with high-latitude coral reefs are different from their tropical counterparts will provide clues to the potential of corals to cope with marginal or changing conditions. However, little is known of the host and symbiont partnerships at high latitudes. Symbiodinium diversity and specificity of high-latitude coral communities were explored using denaturing gradient gel electrophoresis (PCR-DGGE) analysis of the internal transcribed spacer regions (ITS1 and ITS2) of the ribosomal DNA at Lord Howe Island (31°S; Australia), and the Kermadec Islands (29°S; New Zealand). All but one host associated with clade C Symbiodinium, the exception being a soft coral ( Capnella sp.) that contained Symbiodinium B1. Besides ‘host-generalist’ Symbiodinium types C1 and C3, approximately 72% of the Symbiodinium identified were novel C types, and zonation of symbionts in relation to environmental parameters such as depth and turbidity was evident in certain host species. The high-latitude Symbiodinium communities showed little overlap and relatively high diversity compared with communities sampled on the tropical Great Barrier Reef. Although host specificity was maintained in certain species, others shared symbionts and this potential reduction of fidelity at high-latitude locations may be the result of locally challenging and highly variable environmental conditions.

Salvage high-dose-rate interstitial brachytherapy for locally recurrent rectal cancer

Energy Technology Data Exchange (ETDEWEB)

Pellizzon, Antonio Cassio Assis, E-mail: acapellizzon@hcancer.org.br [A.C. Camargo Cancer Center, Sao Paulo, SP (Brazil). Departamento de Radioterapia

2016-05-15

For tumors of the lower third of the rectum, the only safe surgical procedure is abdominal-perineal resection. High-dose-rate interstitial brachytherapy is a promising treatment for local recurrence of previously irradiated lower rectal cancer, due to the extremely high concentrated dose delivered to the tumor and the sparing of normal tissue, when compared with a course of external beam radiation therapy. (author)

Tidal asymmetries of velocity and stratification over a bathymetric depression in a tropical inlet

Science.gov (United States)

Waterhouse, Amy F.; Valle-Levinson, Arnoldo; Morales Pérez, Rubén A.

2012-10-01

Observations of current velocity, sea surface elevation and vertical profiles of density were obtained in a tropical inlet to determine the effect of a bathymetric depression (hollow) on the tidal flows. Surveys measuring velocity profiles were conducted over a diurnal tidal cycle with mixed spring tides during dry and wet seasons. Depth-averaged tidal velocities during ebb and flood tides behaved according to Bernoulli dynamics, as expected. The dynamic balance of depth-averaged quantities in the along-channel direction was governed by along-channel advection and pressure gradients with baroclinic pressure gradients only being important during the wet season. The vertical structure of the along-channel flow during flood tides exhibited a mid-depth maximum with lateral shear enhanced during the dry season as a result of decreased vertical stratification. During ebb tides, along-channel velocities in the vicinity of the hollow were vertically sheared with a weak return flow at depth due to choking of the flow on the seaward slope of the hollow. The potential energy anomaly, a measure of the amount of energy required to fully mix the water column, showed two peaks in stratification associated with ebb tide and a third peak occurring at the beginning of flood. After the first mid-ebb peak in stratification, ebb flows were constricted on the seaward slope of the hollow resulting in a bottom return flow. The sinking of surface waters and enhanced mixing on the seaward slope of the hollow reduced the potential energy anomaly after maximum ebb. The third peak in stratification during early flood occurred as a result of denser water entering the inlet at mid-depth. This dense water mixed with ambient deep waters increasing the stratification. Lateral shear in the along-channel flow across the hollow allowed trapping of less dense water in the surface layers further increasing stratification.

Local level epidemiological analysis of TB in people from a high incidence country of birth

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Massey Peter D

2013-01-01

Full Text Available Abstract Background The setting for this analysis is the low tuberculosis (TB incidence state of New South Wales (NSW, Australia. Local level analysis of TB epidemiology in people from high incidence countries-of-birth (HIC in a low incidence setting has not been conducted in Australia and has not been widely reported. Local level analysis could inform measures such as active case finding and targeted earlier diagnosis. The aim of this study was to use a novel approach to identify local areas in an Australian state that have higher TB rates given the local areas’ country of birth profiles. Methods TB notification data for the three year period 2006–2008 were analysed by grouping the population into those from a high-incidence country-of-birth and the remainder. Results During the study period there were 1401 notified TB cases in the state of NSW. Of these TB cases 76.5% were born in a high-incidence country. The annualised TB notification rate for the high-incidence country-of-birth group was 61.2/100,000 population and for the remainder of the population was 1.8/100,000. Of the 152 Local Government Areas (LGA in NSW, nine had higher and four had lower TB notification rates in their high-incidence country-of-birth populations when compared with the high-incidence country-of-birth population for the rest of NSW. The nine areas had a higher proportion of the population with a country of birth where TB notification rates are >100/100,000. Those notified with TB in the nine areas also had a shorter length of stay in Australia than the rest of the state. The areas with higher TB notification rates were all in the capital city, Sydney. Among LGAs with higher TB notification rates, four had higher rates in both people with a high-incidence country of birth and people not born in a high-incidence country. The age distribution of the HIC population was similar across all areas, and the highest differential in TB rates across areas was in the 5–19

Local level epidemiological analysis of TB in people from a high incidence country of birth.

Science.gov (United States)

Massey, Peter D; Durrheim, David N; Stephens, Nicola; Christensen, Amanda

2013-01-22

The setting for this analysis is the low tuberculosis (TB) incidence state of New South Wales (NSW), Australia. Local level analysis of TB epidemiology in people from high incidence countries-of-birth (HIC) in a low incidence setting has not been conducted in Australia and has not been widely reported. Local level analysis could inform measures such as active case finding and targeted earlier diagnosis. The aim of this study was to use a novel approach to identify local areas in an Australian state that have higher TB rates given the local areas' country of birth profiles. TB notification data for the three year period 2006-2008 were analysed by grouping the population into those from a high-incidence country-of-birth and the remainder. During the study period there were 1401 notified TB cases in the state of NSW. Of these TB cases 76.5% were born in a high-incidence country. The annualised TB notification rate for the high-incidence country-of-birth group was 61.2/100,000 population and for the remainder of the population was 1.8/100,000. Of the 152 Local Government Areas (LGA) in NSW, nine had higher and four had lower TB notification rates in their high-incidence country-of-birth populations when compared with the high-incidence country-of-birth population for the rest of NSW. The nine areas had a higher proportion of the population with a country of birth where TB notification rates are >100/100,000. Those notified with TB in the nine areas also had a shorter length of stay in Australia than the rest of the state. The areas with higher TB notification rates were all in the capital city, Sydney. Among LGAs with higher TB notification rates, four had higher rates in both people with a high-incidence country of birth and people not born in a high-incidence country. The age distribution of the HIC population was similar across all areas, and the highest differential in TB rates across areas was in the 5-19 years age group. Analysing local area TB rates and possible

High Resolution Robust GPS-free Localization for Wireless Sensor Networks and its Applications

KAUST Repository

Mirza, Mohammed

2011-12-12

In this thesis we investigate the problem of robustness and scalability w.r.t. estimating the position of randomly deployed motes/nodes of a Wireless Sensor Network (WSN) without the help of Global Positioning System (GPS) devices. We propose a few applications of range independent localization algorithms that allow the sensors to actively determine their location with high resolution without increasing the complexity of the hardware or any additional device setup. In our first application we try to present a localized and centralized cooperative spectrum sensing using RF sensor networks. This scheme collaboratively sense the spectrum and localize the whole network efficiently and with less difficulty. In second application we try to focus on how efficiently we can localize the nodes, to detect underwater threats, without the use of beacons. In third application we try to focus on 3-Dimensional localization for LTE systems. Our performance evaluation shows that these schemes lead to a significant improvement in localization accuracy compared to the state-of-art range independent localization schemes, without requiring GPS support.

Terrain aided navigation for autonomous underwater vehicles with coarse maps

International Nuclear Information System (INIS)

Zhou, Ling; Cheng, Xianghong; Zhu, Yixian

2016-01-01

Terrain aided navigation (TAN) is a form of geophysical localization technique for autonomous underwater vehicles (AUVs) operating in GPS-denied environments. TAN performance on sensor-rich AUVs has been evaluated in sea trials. However, many challenges remain before TAN can be successfully implemented on sensor-limited AUVs, especially with coarse maps. To improve TAN performance over coarse maps, a Gaussian process (GP) is proposed for the modeling of bathymetric terrain and integrated into the particle filter (GP-PF). GP is applied to provide not only the bathymetric value prediction through learning a set of bathymetric data from coarse maps but also the variance of the prediction. As a measurement update, calculated on bathymetric deviation is performed through the PF to obtain absolute and bounded positioning accuracy. Through the analysis of TAN performance on experimental data for two different terrains with map resolutions of 10–50 m, both the ability of the proposed model to represent the actual bathymetric terrain with accuracy and the effect of the GP-PF for TAN on sensor-limited systems in suited terrain are demonstrated. The experiment results further verify that there is an inverse relationship between the coarseness of the map and the overall TAN accuracy in rough terrains, but there is hardly any relationship between them in relatively flat terrains. (paper)

Saving Salmon Through Advances in Fluvial Remote Sensing: Applying the Optimal Band Ratio Analysis (OBRA) for Bathymetric Mapping of Over 250 km of River Channel and Habitat Classification

Science.gov (United States)

Richardson, R.; Legleiter, C. J.; Harrison, L.

2015-12-01

Salmonids are threatened with extinction across the world from the fragmentation of riverine ecosystems from dams and diversions. In California, efforts to expand the range of spawnable habitat for native salmon by transporting fish around reservoirs is a potentially species saving idea. But, strong scientific evidence of the amount of high quality habitat is required to make these difficult management decisions. Remote sensing has long been used in fluvial settings to identify physical parameters that drive the quality of aquatic habitat; however, the true strength of remote sensing to cover large spatial extents has not been applied with the resolution that is relevant to salmonids. This project utilizes hyperspectral data of over 250 km of the Tuolumne and Merced Rivers to extract depth and bed slope from the wetted channel and NIR LiDAR for the surrounding topography. The Optimal Band Ratio Analysis (OBRA) has proven as an effective tool to create bathymetric maps of river channels in ideal settings with clear water, high amounts of bottom reflectance, and less than 3 meters deep over short distances. Results from this study show that OBRA can be applied over larger riverscapes at high resolutions (0.5 m). The depth and bed slope estimations are used to classify habitat units that are crucial to quantifying the quality and amount of habitat in these river that once produced large populations of native salmonids. As more managers look to expand habitat for these threatened species the tools developed here will be cost effective over the large extents that salmon migrate to spawn.

Principal Component and Cluster Analysis for determining diversification of bottom morphology based on bathymetric profiles from Brepollen (Hornsund, Spitsbergen* The project was partly supported by The Polish Ministry of Sciences and Higher Education Grant No. N N525 350038.

Directory of Open Access Journals (Sweden)

Mateusz Moskalik

2014-01-01

Full Text Available Navigation charts of the post-glacial regions of Arctic fjords tend not to cover regions from which glaciers have retreated. Whilst research vessels can make detailed bathymetric models using multibeam echosounders, they are often too large to enter such areas. To map these regions therefore requires smaller boats carrying single beam echosounders. To obtain morphology models of equivalent quality to those generated using multibeam echosounders, new ways of processing data from single beam echosounders have to be found. The results and comprehensive analysis of such measurements conducted in Brepollen (Hornsund, Spitsbergen are presented in this article. The morphological differentiation of the seafloor was determined by calculating statistical, spectral and wavelet transformation, fractal and median filtration parameters of segments of bathymetric profiles. This set of parameters constituted the input for Principal Component Analysis and then in the form of Principal Components for the Cluster Analysis. As a result of this procedure, three morphological classes are proposed for Brepollen: (i steep slopes (southern Brepollen, (ii flat bottoms (central Brepollen and gentle slopes (the Storebreen glacier valley and the southern part of the Hornbreen glacier valley, (iii the morphologically most diverse region (the central Storebreen valley, the northern part of the Hornbreen glacier valley and the north-eastern part of central Brepollen.

Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning

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Tanel Pärnamaa

2017-05-01

Full Text Available High-throughput microscopy of many single cells generates high-dimensional data that are far from straightforward to analyze. One important problem is automatically detecting the cellular compartment where a fluorescently-tagged protein resides, a task relatively simple for an experienced human, but difficult to automate on a computer. Here, we train an 11-layer neural network on data from mapping thousands of yeast proteins, achieving per cell localization classification accuracy of 91%, and per protein accuracy of 99% on held-out images. We confirm that low-level network features correspond to basic image characteristics, while deeper layers separate localization classes. Using this network as a feature calculator, we train standard classifiers that assign proteins to previously unseen compartments after observing only a small number of training examples. Our results are the most accurate subcellular localization classifications to date, and demonstrate the usefulness of deep learning for high-throughput microscopy.

Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning.

Science.gov (United States)

Pärnamaa, Tanel; Parts, Leopold

2017-05-05

High-throughput microscopy of many single cells generates high-dimensional data that are far from straightforward to analyze. One important problem is automatically detecting the cellular compartment where a fluorescently-tagged protein resides, a task relatively simple for an experienced human, but difficult to automate on a computer. Here, we train an 11-layer neural network on data from mapping thousands of yeast proteins, achieving per cell localization classification accuracy of 91%, and per protein accuracy of 99% on held-out images. We confirm that low-level network features correspond to basic image characteristics, while deeper layers separate localization classes. Using this network as a feature calculator, we train standard classifiers that assign proteins to previously unseen compartments after observing only a small number of training examples. Our results are the most accurate subcellular localization classifications to date, and demonstrate the usefulness of deep learning for high-throughput microscopy. Copyright © 2017 Parnamaa and Parts.

Adjuvant radiochemotherapy in patients with locally advanced high-risk cervical cancer

Energy Technology Data Exchange (ETDEWEB)

Heinzelmann, F.; Henke, G.; Grafenstein, M. von; Weidner, N.; Paulsen, F.; Bamberg, M.; Weinmann, M. [Tuebingen Univ. (Germany). Dept. of Radiation Oncology; Staebler, A. [Tuebingen Univ. (Germany). Div. of Gynecologic Pathology; Brucker, S. [Tuebingen Univ. (Germany). Dept. of Gynecology

2012-07-15

Background and purpose: The aim of this retrospective study was to analyze the outcome of patients with locally advanced cervical carcinoma treated by adjuvant radiochemotherapy and to determine risk factors for local and distant relapse. Furthermore, acute and late effects of treatment were recorded. Patients and methods: A total of 72 patients with FIGO stages I-III cervical carcinoma were treated by radical hysterectomy, pelvic lymphadenectomy, and postoperative radiochemotherapy. Only patients with positive pelvic lymph nodes, parametrial involvement, positive margins, or tumor bulk were eligible. Patients were irradiated with a standard pelvic field (50.4 Gy in 28 fractions). The majority of patients received platinum-based chemotherapy. Results: After a median follow-up of 37 months, estimated 1-, 2-, and 4-year disease-free survival (DFS) and overall survival (OS) rates were 89%, 80%, 68% and 95%, 88%, 76%, respectively. Nine of the 72 patients had pelvic recurrences including only 1 isolated local failure; 23 of the 72 patients presented with distant relapse. The majority of relapses occurred within the first 3 years after adjuvant treatment. The number of positive pelvic lymph nodes (> 1) was the strongest prognostic factor for DFS. Treatment was well tolerated with transient acute hematologic ({proportional_to}30%) and gastrointestinal ({proportional_to}30%) grade 3 toxicity. Small bowel obstruction ({proportional_to}6%) was the only important late sequelae. Conclusion: Adjuvant radiochemotherapy in patients with advanced cervical cancer and several risk factors is highly effective to prevent local relapse. Future efforts to improve outcome should be placed on improvement of systemic control especially in subgroups with high-risk features for distant relapse. Combined treatment was well tolerated with moderate acute and late toxicity. (orig.)

Highly localized distributed Brillouin scattering response in a photonic integrated circuit

Science.gov (United States)

Zarifi, Atiyeh; Stiller, Birgit; Merklein, Moritz; Li, Neuton; Vu, Khu; Choi, Duk-Yong; Ma, Pan; Madden, Stephen J.; Eggleton, Benjamin J.

2018-03-01

The interaction of optical and acoustic waves via stimulated Brillouin scattering (SBS) has recently reached on-chip platforms, which has opened new fields of applications ranging from integrated microwave photonics and on-chip narrow-linewidth lasers, to phonon-based optical delay and signal processing schemes. Since SBS is an effect that scales exponentially with interaction length, on-chip implementation on a short length scale is challenging, requiring carefully designed waveguides with optimized opto-acoustic overlap. In this work, we use the principle of Brillouin optical correlation domain analysis to locally measure the SBS spectrum with high spatial resolution of 800 μm and perform a distributed measurement of the Brillouin spectrum along a spiral waveguide in a photonic integrated circuit. This approach gives access to local opto-acoustic properties of the waveguides, including the Brillouin frequency shift and linewidth, essential information for the further development of high quality photonic-phononic waveguides for SBS applications.

Highly localized distributed Brillouin scattering response in a photonic integrated circuit

Directory of Open Access Journals (Sweden)

Atiyeh Zarifi

2018-03-01

Full Text Available The interaction of optical and acoustic waves via stimulated Brillouin scattering (SBS has recently reached on-chip platforms, which has opened new fields of applications ranging from integrated microwave photonics and on-chip narrow-linewidth lasers, to phonon-based optical delay and signal processing schemes. Since SBS is an effect that scales exponentially with interaction length, on-chip implementation on a short length scale is challenging, requiring carefully designed waveguides with optimized opto-acoustic overlap. In this work, we use the principle of Brillouin optical correlation domain analysis to locally measure the SBS spectrum with high spatial resolution of 800 μm and perform a distributed measurement of the Brillouin spectrum along a spiral waveguide in a photonic integrated circuit. This approach gives access to local opto-acoustic properties of the waveguides, including the Brillouin frequency shift and linewidth, essential information for the further development of high quality photonic-phononic waveguides for SBS applications.

Evaluating the potential for remote bathymetric mapping of a turbid, sand-bed river: 2. application to hyperspectral image data from the Platte River

Science.gov (United States)

Legleiter, Carl J.; Kinzel, Paul J.; Overstreet, Brandon T.

2011-01-01

This study examined the possibility of mapping depth from optical image data in turbid, sediment-laden channels. Analysis of hyperspectral images from the Platte River indicated that depth retrieval in these environments is feasible, but might not be highly accurate. Four methods of calibrating image-derived depth estimates were evaluated. The first involved extracting image spectra at survey point locations throughout the reach. These paired observations of depth and reflectance were subjected to optimal band ratio analysis (OBRA) to relate (R2 = 0.596) a spectrally based quantity to flow depth. Two other methods were based on OBRA of data from individual cross sections. A fourth strategy used ground-based reflectance measurements to derive an OBRA relation (R2 = 0.944) that was then applied to the image. Depth retrieval accuracy was assessed by visually inspecting cross sections and calculating various error metrics. Calibration via field spectroscopy resulted in a shallow bias but provided relative accuracies similar to image-based methods. Reach-aggregated OBRA was marginally superior to calibrations based on individual cross sections, and depth retrieval accuracy varied considerably along each reach. Errors were lower and observed versus predicted regression R2 values higher for a relatively simple, deeper site than a shallower, braided reach; errors were 1/3 and 1/2 the mean depth for the two reaches. Bathymetric maps were coherent and hydraulically reasonable, however, and might be more reliable than implied by numerical metrics. As an example application, linear discriminant analysis was used to produce a series of depth threshold maps for characterizing shallow-water habitat for roosting cranes.

B4G local area: high level requirements and system design

DEFF Research Database (Denmark)

Mogensen, Preben; Pajukoski, Kari; Raaf, Bernhard

2012-01-01

A next generation Beyond 4G (B4G) radio access technology is expected to become available around 2020 in order to cope with the exponential increase of mobile data traffic. In this paper, research motivations and high level requirements for a B4G local area concept are discussed. Our suggestions ...

Root-type-specific plasticity in response to localized high nitrate supply in maize (Zea mays).

Science.gov (United States)

Yu, Peng; Hochholdinger, Frank; Li, Chunjian

2015-10-01

Shoot-borne roots contribute to most of the nutrient uptake throughout the life cycle of maize (Zea mays). Compared with numerous studies with embryonic roots, detailed information on the phenotypic plasticity of shoot-borne roots in response to a heterogeneous nitrogen supply is scarce. The present study therefore provides a comprehensive profile of fine-scale plastic responses of distinct root types to localized high nitrate supply. Seedlings of the maize inbred line B73 were grown in split-root systems. The anatomy and morphological plasticity of the primary root and the roots initiated from the 2nd, 5th and 7th shoot nodes, and their lateral roots, were studied in response to local high nitrate supply to one side of the root system. In contrast to the insensitivity of axial roots, local high nitrate supply increased the length of 1st-order lateral roots on the primary root and the three whorls of shoot-borne roots at different growth stages, and increased the density of 1st-order lateral roots on the 7th shoot-borne root after silking. The length and density of 2nd-order lateral roots on the three whorls of shoot-borne roots displayed a more flexible response to local high nitrate than 1st-order lateral roots. Root diameter and number, and total area and diameter of metaxylem vessels increased from the primary root to early and then later developed shoot-borne roots, which showed a positive relationship with shoot growth and N accumulation. Maize axial roots and lateral roots responded differently to local high nitrate, and this was related to their function. The extent of morphological plasticity of lateral roots in response to local high nitrate depended on the initiation time of the shoot-borne roots on which the lateral roots developed. Morphological plasticity was higher on 2nd-order than on 1st-order lateral roots. The results suggest that higher order lateral root branching might be a potential target for genetic improvement in future maize breeding. �

Method for local temperature measurement in a nanoreactor for in situ high-resolution electron microscopy.

Science.gov (United States)

Vendelbo, S B; Kooyman, P J; Creemer, J F; Morana, B; Mele, L; Dona, P; Nelissen, B J; Helveg, S

2013-10-01

In situ high-resolution transmission electron microscopy (TEM) of solids under reactive gas conditions can be facilitated by microelectromechanical system devices called nanoreactors. These nanoreactors are windowed cells containing nanoliter volumes of gas at ambient pressures and elevated temperatures. However, due to the high spatial confinement of the reaction environment, traditional methods for measuring process parameters, such as the local temperature, are difficult to apply. To address this issue, we devise an electron energy loss spectroscopy (EELS) method that probes the local temperature of the reaction volume under inspection by the electron beam. The local gas density, as measured using quantitative EELS, is combined with the inherent relation between gas density and temperature, as described by the ideal gas law, to obtain the local temperature. Using this method we determined the temperature gradient in a nanoreactor in situ, while the average, global temperature was monitored by a traditional measurement of the electrical resistivity of the heater. The local gas temperatures had a maximum of 56 °C deviation from the global heater values under the applied conditions. The local temperatures, obtained with the proposed method, are in good agreement with predictions from an analytical model. Copyright © 2013 Elsevier B.V. All rights reserved.

High-precision spatial localization of mouse vocalizations during social interaction.

Science.gov (United States)

Heckman, Jesse J; Proville, Rémi; Heckman, Gert J; Azarfar, Alireza; Celikel, Tansu; Englitz, Bernhard

2017-06-07

Mice display a wide repertoire of vocalizations that varies with age, sex, and context. Especially during courtship, mice emit ultrasonic vocalizations (USVs) of high complexity, whose detailed structure is poorly understood. As animals of both sexes vocalize, the study of social vocalizations requires attributing single USVs to individuals. The state-of-the-art in sound localization for USVs allows spatial localization at centimeter resolution, however, animals interact at closer ranges, involving tactile, snout-snout exploration. Hence, improved algorithms are required to reliably assign USVs. We develop multiple solutions to USV localization, and derive an analytical solution for arbitrary vertical microphone positions. The algorithms are compared on wideband acoustic noise and single mouse vocalizations, and applied to social interactions with optically tracked mouse positions. A novel, (frequency) envelope weighted generalised cross-correlation outperforms classical cross-correlation techniques. It achieves a median error of ~1.4 mm for noise and ~4-8.5 mm for vocalizations. Using this algorithms in combination with a level criterion, we can improve the assignment for interacting mice. We report significant differences in mean USV properties between CBA mice of different sexes during social interaction. Hence, the improved USV attribution to individuals lays the basis for a deeper understanding of social vocalizations, in particular sequences of USVs.

Laser-induced local activation of Mg-doped GaN with a high lateral resolution for high power vertical devices

Science.gov (United States)

Kurose, Noriko; Matsumoto, Kota; Yamada, Fumihiko; Roffi, Teuku Muhammad; Kamiya, Itaru; Iwata, Naotaka; Aoyagi, Yoshinobu

2018-01-01

A method for laser-induced local p-type activation of an as-grown Mg-doped GaN sample with a high lateral resolution is developed for realizing high power vertical devices for the first time. As-grown Mg-doped GaN is converted to p-type GaN in a confined local area. The transition from an insulating to a p-type area is realized to take place within about 1-2 μm fine resolution. The results show that the technique can be applied in fabricating the devices such as vertical field effect transistors, vertical bipolar transistors and vertical Schottkey diode so on with a current confinement region using a p-type carrier-blocking layer formed by this technique.

Bathymetric and regional changes in benthic macrofaunal assemblages on the deep Eastern Brazilian margin, SW Atlantic

Science.gov (United States)

Bernardino, Angelo Fraga; Berenguer, Vanessa; Ribeiro-Ferreira, Venina P.

2016-05-01

Deep-sea continental slopes have valuable mineral and biological resources in close proximity to diverse, undersampled and fragile marine benthic ecosystems. The eastern Brazilian Continental Margin (19.01°S to 21.06°S, 37.88°W to 40.22°W) is an important economic region for both fishing and oil industries, but is poorly understood with respect to the structure of the soft-sediment benthic fauna, their regional distribution and their bathymetric patterns. To identify spatial and temporal patterns of benthic macrofaunal assemblages on the slope (400 to 3000 m), the Espirito Santo Basin Assessment Project (AMBES, coordinated by Cenpes-Petrobras) sampled 42 stations across the Brazilian Eastern Slope during both Summer 2012 and Winter 2013. We found a significant decrease in macrofaunal abundance at the 400 m isobath along the slope near the northern region of the Espirito Santo Basin, suggesting benthic responses to upwelling events towards the south in Campos Basin and southern Espirito Santo Basin. The taxonomic diversity and assemblage composition also changed significantly across depth zones with mid-slope peaks of diversity at 1000-1300 m. In general, macrofaunal assemblages were strongly related to slope depth, suggesting a strong influence of productivity gradients and water mass distribution on this oligotrophic margin. Sediment grain size was marginally important to macrofaunal composition on the upper slope. In general, macrofaunal assemblages on the slope of Espirito Santo Basin are similar to other areas of the SE Brazilian margin, but regional changes in response to productivity and depth need to be considered for management strategies in the face of increasing economic activities off-shore.

Effect of high-volume systematic local infiltration analgesia in Caesarean section

DEFF Research Database (Denmark)

Larsen, Klaus Richter; Kristensen, B B; Rasmussen, M A

2015-01-01

BACKGROUND: Pain after Caesarean section is often treated with opioids with a risk of side effects. Wound infiltration with local anaesthetics is effective and has few side effects, but volume vs. dose concentration has not been examined. METHODS: Ninety patients scheduled for elective Caesarean...... found concerning time spent in the PACU, to first mobilisation or in number of women with nausea/vomiting (P ≥ 0.05). No complications related to ropivacaine were observed. CONCLUSIONS: Systematic infiltration with a high concentration, low volume compared with low concentration, high volume showed...

Mapping river bathymetry with a small footprint green LiDAR: Applications and challenges

Science.gov (United States)

Kinzel, Paul J.; Legleiter, Carl; Nelson, Jonathan M.

2013-01-01

Airborne bathymetric Light Detection And Ranging (LiDAR) systems designed for coastal and marine surveys are increasingly sought after for high-resolution mapping of fluvial systems. To evaluate the potential utility of bathymetric LiDAR for applications of this kind, we compared detailed surveys collected using wading and sonar techniques with measurements from the United States Geological Survey’s hybrid topographic⁄ bathymetric Experimental Advanced Airborne Research LiDAR (EAARL). These comparisons, based upon data collected from the Trinity and Klamath Rivers, California, and the Colorado River, Colorado, demonstrated

Local imaging of high mobility two-dimensional electron systems with virtual scanning tunneling microscopy

Energy Technology Data Exchange (ETDEWEB)

Pelliccione, M. [Department of Applied Physics, Stanford University, 348 Via Pueblo Mall, Stanford, California 94305 (United States); Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States); Department of Physics, University of California, Santa Barbara, Santa Barbara, California 93106 (United States); Bartel, J.; Goldhaber-Gordon, D. [Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States); Department of Physics, Stanford University, 382 Via Pueblo Mall, Stanford, California 94305 (United States); Sciambi, A. [Department of Applied Physics, Stanford University, 348 Via Pueblo Mall, Stanford, California 94305 (United States); Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States); Pfeiffer, L. N.; West, K. W. [Department of Electrical Engineering, Princeton University, Princeton, New Jersey 08544 (United States)

2014-11-03

Correlated electron states in high mobility two-dimensional electron systems (2DESs), including charge density waves and microemulsion phases intermediate between a Fermi liquid and Wigner crystal, are predicted to exhibit complex local charge order. Existing experimental studies, however, have mainly probed these systems at micron to millimeter scales rather than directly mapping spatial organization. Scanning probes should be well-suited to study the spatial structure of these states, but high mobility 2DESs are found at buried semiconductor interfaces, beyond the reach of conventional scanning tunneling microscopy. Scanning techniques based on electrostatic coupling to the 2DES deliver important insights, but generally with resolution limited by the depth of the 2DES. In this letter, we present our progress in developing a technique called “virtual scanning tunneling microscopy” that allows local tunneling into a high mobility 2DES. Using a specially designed bilayer GaAs/AlGaAs heterostructure where the tunnel coupling between two separate 2DESs is tunable via electrostatic gating, combined with a scanning gate, we show that the local tunneling can be controlled with sub-250 nm resolution.

Treatment of locally advanced breast carcinoma with high-dose external beam supervoltage radiotherapy

International Nuclear Information System (INIS)

Brufman, G.; Weshler, Z.; Prosnitz, L.R.; Fuks, Z.

1981-01-01

Between 1960 and 1978, 87 patients with locally advanced Tsub(3-4)Nsub(0-3)M 0 carcinoma of the breast were treated with 5,000 to 8,000 rad of external beam supervoltage radiotherapy. Initial clinical eradication of the tumour was observed in 76 of 87 cases (87%), but the actuarial probability of local control at 5 yr was only 53%. Furthermore, the actuarial probability of disease-free survival was 25% at 5 yr and 13% at 10 yr. Most of the patients eventually succumbed to metastatic breast carcinoma and the actuarial survival at 5 yr was 43% and at 10 yr, 16%. The addition of adjuvant low-dose chemotherapy, given to 13 patients, did not affect the rates of local control, survival or disease-free survival. The most common long-term complication was extensive and deforming radiation-induced fibrosis of the treated breast. The actuarial probability of 10-yr survival without a local recurrence and without severe fibrosis of the treated breast was only 17.5%. The role of adjuvant high-dose chemotherapy in the treatment of locally advanced breast carcinoma and the possible use of improved radiotherapy techniques to achieve a more effective long-term local control and a more desirable cosmetic end result are discussed. (author)

High-precision atom localization via controllable spontaneous emission in a cycle-configuration atomic system.

Science.gov (United States)

Ding, Chunling; Li, Jiahua; Yu, Rong; Hao, Xiangying; Wu, Ying

2012-03-26

A scheme for realizing two-dimensional (2D) atom localization is proposed based on controllable spontaneous emission in a coherently driven cycle-configuration atomic system. As the spatial-position-dependent atom-field interaction, the frequency of the spontaneously emitted photon carries the information about the position of the atom. Therefore, by detecting the emitted photon one could obtain the position information available, and then we demonstrate high-precision and high-resolution 2D atom localization induced by the quantum interference between the multiple spontaneous decay channels. Moreover, we can achieve 100% probability of finding the atom at an expected position by choosing appropriate system parameters under certain conditions.

Chemotherapy and novel therapeutics before radical prostatectomy for high-risk clinically localized prostate cancer.

Science.gov (United States)

Cha, Eugene K; Eastham, James A

2015-05-01

Although both surgery and radiation are potential curative options for men with clinically localized prostate cancer, a significant proportion of men with high-risk and locally advanced disease will demonstrate biochemical and potentially clinical progression of their disease. Neoadjuvant systemic therapy before radical prostatectomy (RP) is a logical strategy to improve treatment outcomes for men with clinically localized high-risk prostate cancer. Furthermore, delivery of chemotherapy and other systemic agents before RP affords an opportunity to explore the efficacy of these agents with pathologic end points. Neoadjuvant chemotherapy, primarily with docetaxel (with or without androgen deprivation therapy), has demonstrated feasibility and safety in men undergoing RP, but no study to date has established the efficacy of neoadjuvant chemotherapy or neoadjuvant chemohormonal therapies. Other novel agents, such as those targeting the vascular endothelial growth factor receptor, epidermal growth factor receptor, platelet-derived growth factor receptor, clusterin, and immunomodulatory therapeutics, are currently under investigation. Copyright © 2015 Elsevier Inc. All rights reserved.

Local level epidemiological analysis of TB in people from a high incidence country of birth

OpenAIRE

Massey Peter D; Durrheim David N; Stephens Nicola; Christensen Amanda

2013-01-01

Abstract Background The setting for this analysis is the low tuberculosis (TB) incidence state of New South Wales (NSW), Australia. Local level analysis of TB epidemiology in people from high incidence countries-of-birth (HIC) in a low incidence setting has not been conducted in Australia and has not been widely reported. Local level analysis could inform measures such as active case finding and targeted earlier diagnosis. The aim of this study was to use a novel approach to identify local ar...

Local high voltage radiotherapy with curative intent for prostatic carcinoma

International Nuclear Information System (INIS)

Jacobi, G.H.; Kurth, K.H.; Hohenfellner, R.

1979-01-01

In a 10-year interval 179 patients with prostatic carcinoma were treated by cobalt-60 teletherapy (7600 R). A selected group of 47 patients with localized disease and irradiated with curative intent had serial prostatic biopsies and were analized after a minimum follow-up of 1 year. Biopsies of half of the patients rendered definitively negative, on an average 14 months after radiotherapy. 8 patients with initial negative biopsy changed to positive secondarily. In one third of the patients histological conversion was missed, considered as radiation persister. Persistent carcinoma were of predominant low grade. 5 patients developed distant metastases 30 months after irradiation on an average. These patients had persistent positive tissue studies. Over all cumulative 5-years survival was 89%. In patients with prostatic carcinoma and local high voltage radiotherapy with curative intent (stage A through C) serial prostatic biopsies to document therapy effect seen mandatory. (orig.) 891 AJ/orig. 892 BRE [de

Kinematics of Local, High-Velocity K dwarfs in the SUPERBLINK Proper Motion Catalog

Science.gov (United States)

Kim, Bokyoung; Lepine, Sebastien

2018-01-01

We present a study of the kinematics of 345,480 K stars within 2 kpc of the Sun, based on data from the SUPERBLINK catalog of stars with high proper motions (> 40 mas/yr), combined with data from the 2MASS survey and from the first GAIA release, which together yields proper motions accurate to ~2 mas/yr. All K dwarfs were selected based on their G-K colors, and photometric distances were estimated from a re-calibrated color-magnitude relationship for K dwarfs. We plot transverse velocities VT in various directions on the sky, to examine the local distribution of K dwarfs in velocity space. We have also obtained radial velocity information for a subsample of 10,128 stars, from RAVE and SDSS DR12, which we use to construct spatial velocity (U, V, W) plots. About a third (123,350) of the stars are high-velocity K dwarfs, with motions consistent with the local Galactic halo population. Our kinematic analysis suggests that their velocity-space distribution is very uniform, and we find no evidence of substructure that might arise, e.g., from local streams or moving groups.

Local Energies and Energy Fluctuations — Applied to the High Entropy Alloy CrFeCoNi

Science.gov (United States)

Fukushima, Tetsuya; Katayama-Yoshida, Hiroshi; Sato, Kazunori; Ogura, Masako; Zeller, Rudolf; Dederichs, Peter H.

2017-11-01

High entropy alloys show a variety of fascinating properties like high hardness, wear resistance, corrosion resistance, etc. They are random solid solutions of many components with rather high concentrations. We perform ab-initio calculations for the high entropy alloy CrFeCoNi, which equal concentration of 25% for each element. By the KKRnano program package, which is based on an order-N screened Korringa-Kohn-Rostoker Green's function method, we consider a face-centered cubic (FCC) supercell with 1372 randomly distributed elements, and in addition also smaller supercells with 500 and 256 atoms. It is found from our calculations that the local moments of the Cr atoms show a large environmental variation, ranging from -1.70 μB to +1.01 μB with an average of about -0.51 μB. We present a new method to calculate "local energies" of all atoms. This is based on the partitioning of the whole space into Voronoi cells and allows to calculate the energetic contribution of each atomic cell to the total energy of the supercell. The supercell calculations show very large variations of the local energies, analogous to the variations of the local moments. This shows that the random solid solution is not stable and has a tendency to form an L12-structure with the Cr-atoms ordered at the corner of the cube and the elements Fe, Co, and Ni randomly distributed on the three other FCC sublattices. For this structure the variation of the local moments are much smaller.

New possibilities for testing local realism in high energy physics

International Nuclear Information System (INIS)

Li Junli; Qiao Congfeng

2009-01-01

The three photons from the dominant ortho-positronium decay and two vector mesons from the η c exclusive decays are found to be in tripartite and high-dimensional entangled states, respectively. These two classes of entangled states possess the Hardy type nonlocality and allow a priori for quantum mechanics vs local realism test via Bell inequalities. The experimental realizations are shown to be feasible, and a concrete scheme to fulfill the test in experiment via two-vector-meson entangled state is proposed.

Fast neutron radiotherapy for soft tissue and cartilaginous sarcomas at high risk for local recurrence

International Nuclear Information System (INIS)

Schwartz, David L.; Einck, John; Bellon, Jennifer; Laramore, George E.

2001-01-01

Purpose: The practice policy at the University of Washington has been to employ fast neutron radiotherapy for soft tissue sarcoma lesions with prognostic features predictive for poor local control. These include gross residual disease/inoperable disease, recurrent disease, and contaminated surgical margins. Cartilaginous sarcomas have also been included in this high-risk group. This report updates and expands our previously described experience with this approach. Methods and Materials: Eighty-nine soft tissue sarcoma lesions in 72 patients were treated with neutron radiotherapy in our department between 1984 and 1996. Six patients, each with solitary lesions, were excluded from analysis due to lack of follow-up. Seventy-three percent were treated with fast neutron radiation alone, the rest with a combination of neutrons and photons. Median neutron dose was 18.3 nGy (range 4.8-22). Forty-two patients with solitary lesions were treated with curative intent. Thirty-one patients (including 7 previously treated with neutrons) with 41 lesions were treated with the goal of local palliation. Tumors were predominantly located in the extremity and torso. Thirty of 35 (85%) of curative group patients treated postoperatively had close or positive surgical margins. Thirty-four (82%) lesions treated for palliation were unresectable. Thirty-five patients (53%) were treated at the time of recurrence. Median tumor size at initial presentation was 8.0 cm (range 0.6-29), median treated gross disease size was 5.0 cm (range 1-22), and 46/69 evaluable lesions (67%) were judged to be of intermediate to high histologic grade. Fourteen patients (21%) had chondrosarcomas. Results: Median follow-up was 6 months (range 2-47) and 38 months (range 2-175) for the palliative and curative groups, respectively. Kaplan-Meier estimates were obtained for probability of local relapse-free survival (68%), distant disease-free survival (59%), cause-specific survival (68%), and overall survival (66%) at

Localization-based super-resolution imaging meets high-content screening.

Science.gov (United States)

Beghin, Anne; Kechkar, Adel; Butler, Corey; Levet, Florian; Cabillic, Marine; Rossier, Olivier; Giannone, Gregory; Galland, Rémi; Choquet, Daniel; Sibarita, Jean-Baptiste

2017-12-01

Single-molecule localization microscopy techniques have proven to be essential tools for quantitatively monitoring biological processes at unprecedented spatial resolution. However, these techniques are very low throughput and are not yet compatible with fully automated, multiparametric cellular assays. This shortcoming is primarily due to the huge amount of data generated during imaging and the lack of software for automation and dedicated data mining. We describe an automated quantitative single-molecule-based super-resolution methodology that operates in standard multiwell plates and uses analysis based on high-content screening and data-mining software. The workflow is compatible with fixed- and live-cell imaging and allows extraction of quantitative data like fluorophore photophysics, protein clustering or dynamic behavior of biomolecules. We demonstrate that the method is compatible with high-content screening using 3D dSTORM and DNA-PAINT based super-resolution microscopy as well as single-particle tracking.

High-intensity interval training has beneficial effects on cardiac remodeling through local renin-angiotensin system modulation in mice fed high-fat or high-fructose diets.

Science.gov (United States)

de Oliveira Sá, Guilherme; Dos Santos Neves, Vívian; de Oliveira Fraga, Shyrlei R; Souza-Mello, Vanessa; Barbosa-da-Silva, Sandra

2017-11-15

HIIT (high-intensity interval training) has the potential to reduce cardiometabolic risk factors, but the effects on cardiac remodeling and local RAS (renin-angiotensin system) in mice fed high-fat or high-fructose diets still need to be fully addressed. Sixty male C57BL/6 mice (12weeks old) were randomly divided into three groups, control (C), High-fat (HF), or High-fructose diet (HRU) and were monitored for eight weeks before being submitted to the HIIT. Each group was randomly assigned to 2 subgroups, one subgroup was started on a 12-week HIIT protocol (T=trained group), while the other subgroup remained non-exercised (NT=not-trained group). HIIT reduced BM and systolic blood pressure in high-fat groups, while enhanced insulin sensitivity after high-fat or high-fructose intake. Moreover, HIIT reduced left ventricular hypertrophy in HF-T and HFRU-T. Notably, HIIT modulated key factors in the local left ventricular renin-angiotensin-system (RAS): reduced protein expression of renin, ACE (Angiotensin-converting enzyme), and (Angiotensin type 2 receptor) AT2R in HF-T and HFRU-T groups but reduced (Angiotensin type 1 receptor) AT1R protein expression only in the high-fat trained group. HIIT modulated ACE2/Ang (1-7)/Mas receptor axis. ACE2 mRNA gene expression was enhanced in HF-T and HFRU-T groups, complying with elevated Mas (Mas proto-oncogene, G protein-coupled receptor) receptor mRNA gene expression after HIIT. This study shows the effectiveness of HIIT sessions in producing improvements in insulin sensitivity and mitigating LV hypertrophy, though hypertension was controlled only in the high-fat-fed submitted to HIIT protocol. Local RAS system in the heart mediates these findings and receptor MAS seems to play a pivotal role when it comes to the amelioration of cardiac structural and functional remodeling due to HIIT. Copyright © 2017 Elsevier Inc. All rights reserved.

Measurement of the local void fraction at high pressures in a heating channel

International Nuclear Information System (INIS)

Martin, R.

1969-01-01

Void fraction measurements were made in two phase flow boiling systems at high pressures in a uniformly heated, rectangular channel with a high aspect ratio. The local void fraction values were calculated from measurements of the absorption of a thin collimated X-ray beam (2 mm x 0.05 mm). The mean void fraction in a horizontal section results from integration of the local values across the section. At a fixed measuring station the quality and- void fraction were varied by changing the heat flux, flow rate and pressure systematically. Two channels were used differing in length and thickness (150.8 cm x 5.3 cm x 0.2 cm and the significant features of this study are: -1) The void fraction measurements are among the first obtained at such high pressure (80 to 140 kg/cm 2 ); -2) In the experimental region under consideration the measurements are systematic and numerous enough to allow accurate interpolations: mass velocity from 50 to 220 g/cm 2 .s, heat flux from 40 to 170 W/cm 2 and calculated steam quality from -0.2 to 0.2; -3) Many tests were performed under local boiling conditions with the mean temperature of the fluid below the saturation temperature; and -4) These results were compared to the predictions of certain models presented in the literature and simple empirical formulae were developed to fit the experimental results. (author) [fr

Local-scale high-resolution atmospheric dispersion model using large-eddy simulation. LOHDIM-LES

International Nuclear Information System (INIS)

Nakayama, Hiromasa; Nagai, Haruyasu

2016-03-01

We developed LOcal-scale High-resolution atmospheric DIspersion Model using Large-Eddy Simulation (LOHDIM-LES). This dispersion model is designed based on LES which is effective to reproduce unsteady behaviors of turbulent flows and plume dispersion. The basic equations are the continuity equation, the Navier-Stokes equation, and the scalar conservation equation. Buildings and local terrain variability are resolved by high-resolution grids with a few meters and these turbulent effects are represented by immersed boundary method. In simulating atmospheric turbulence, boundary layer flows are generated by a recycling turbulent inflow technique in a driver region set up at the upstream of the main analysis region. This turbulent inflow data are imposed at the inlet of the main analysis region. By this approach, the LOHDIM-LES can provide detailed information on wind velocities and plume concentration in the investigated area. (author)

More than a century of bathymetric observations and present-day shallow sediment characterization in Belfast Bay, Maine, USA: implications for pockmark field longevity

Science.gov (United States)

Brothers, Laura L.; Kelley, Joseph T.; Belknap, Daniel F.; Barnhardt, Walter A.; Andrews, Brian D.; Maynard, Melissa Landon

2011-08-01

Mechanisms and timescales responsible for pockmark formation and maintenance remain uncertain, especially in areas lacking extensive thermogenic fluid deposits (e.g., previously glaciated estuaries). This study characterizes seafloor activity in the Belfast Bay, Maine nearshore pockmark field using (1) three swath bathymetry datasets collected between 1999 and 2008, complemented by analyses of shallow box-core samples for radionuclide activity and undrained shear strength, and (2) historical bathymetric data (report and smooth sheets from 1872, 1947, 1948). In addition, because repeat swath bathymetry surveys are an emerging data source, we present a selected literature review of recent studies using such datasets for seafloor change analysis. This study is the first to apply the method to a pockmark field, and characterizes macro-scale (>5 m) evolution of tens of square kilometers of highly irregular seafloor. Presence/absence analysis yielded no change in pockmark frequency or distribution over a 9-year period (1999-2008). In that time pockmarks did not detectably enlarge, truncate, elongate, or combine. Historical data indicate that pockmark chains already existed in the 19th century. Despite the lack of macroscopic changes in the field, near-bed undrained shear-strength values of less than 7 kPa and scattered downcore 137Cs signatures indicate a highly disturbed setting. Integrating these findings with independent geophysical and geochemical observations made in the pockmark field, it can be concluded that (1) large-scale sediment resuspension and dispersion related to pockmark formation and failure do not occur frequently within this field, and (2) pockmarks can persevere in a dynamic estuarine setting that exhibits minimal modern fluid venting. Although pockmarks are conventionally thought to be long-lived features maintained by a combination of fluid venting and minimal sediment accumulation, this suggests that other mechanisms may be equally active in

Changes in scleractinian coral Seriatopora hystrix morphology and its endocellular Symbiodinium characteristics along a bathymetric gradient from shallow to mesophotic reef

Science.gov (United States)

Nir, O.; Gruber, D. F.; Einbinder, S.; Kark, S.; Tchernov, D.

2011-12-01

The algae living endosymbiotically within coral are thought to increase algal pigmentation with increasing depth to capture the diminishing light. Here, we follow distribution of the hermatypic coral Seriatopora hystrix along a 60-m bathymetric gradient in the Gulf of Eilat, Red Sea, to study coral ecophysiology and response to light regimes. Combining work on coral morphology, pigment content and genotyping of the photosymbiont, we found that total chlorophyll concentration per zooxanthellae cell and the dark- and light-acclimated quantum yield of photosystem II did not vary significantly along the 60-m gradient. However, the chlorophyll a/c ratio increased with depth. This suggests that the symbiotic algae in S. hystrix possess a mechanism for acclimatization or adaptation that differs from previously described pathways. The accepted photoacclimatory process involves an increase in chlorophyll content per alga as light intensity decreases. Based on corallite and branch morphology, this research suggests that S. hystrix has two depth-dependent ecophenotypes. Above 10 m depth, S. hystrix exhibits sturdier colony configurations with thick branches, while below 30 m depth, colonies are characterized by thin branches and the presence of a larger polyp area. Between 10 and 30 m depth, both ecophenotypes are present, suggesting that corallite morphology may act as another axis of photoacclimation with depth.

Localized corrosion of high alloyed austenitic stainless steels

International Nuclear Information System (INIS)

Morach, R.; Schmuki, P.; Boehni, H.

1992-01-01

The susceptibility of several high alloyed stainless steels against localized corrosion was investigated by traditional potentiostatic and -kinetic methods and the current transient technique. Different test cells, proposed in literature, were evaluated for use in testing of plate materials. The AVESTA-cell showed to be not useful for potentiokinetic current density potential curves, but useable for pitting experiments. After pickling and prepassivation epoxy embedded materials proved to be resistant to crevice corrosion at the metal-resin interface. The electrode in form of a wire was the most reliable crevice free cell design. The grinding of the samples in the pretreatment procedure was found to have a large effect on the pitting corrosion behaviour. Using different paper types with varying grit, a drop in pitting potential for rougher surfaces and an increase in metastable pitting activity was found. Increasing surface roughness led also to changes in the electronic structure of the passive film reflected by a lower bandgap energy. High alloyed stainless steels showed no breakdown potential within the examined potential range. Compared to 18/8 type stainless steels significantly less transients were found. The number of transients decreases with increasing molybdenum and chromium content

Remote measurement of river discharge using thermal particle image velocimetry (PIV) and various sources of bathymetric information

Science.gov (United States)

Legleiter, Carl; Kinzel, Paul J.; Nelson, Jonathan M.

2017-01-01

Although river discharge is a fundamental hydrologic quantity, conventional methods of streamgaging are impractical, expensive, and potentially dangerous in remote locations. This study evaluated the potential for measuring discharge via various forms of remote sensing, primarily thermal imaging of flow velocities but also spectrally-based depth retrieval from passive optical image data. We acquired thermal image time series from bridges spanning five streams in Alaska and observed strong agreement between velocities measured in situ and those inferred by Particle Image Velocimetry (PIV), which quantified advection of thermal features by the flow. The resulting surface velocities were converted to depth-averaged velocities by applying site-specific, calibrated velocity indices. Field spectra from three clear-flowing streams provided strong relationships between depth and reflectance, suggesting that, under favorable conditions, spectrally-based bathymetric mapping could complement thermal PIV in a hybrid approach to remote sensing of river discharge; this strategy would not be applicable to larger, more turbid rivers, however. A more flexible and efficient alternative might involve inferring depth from thermal data based on relationships between depth and integral length scales of turbulent fluctuations in temperature, captured as variations in image brightness. We observed moderately strong correlations for a site-aggregated data set that reduced station-to-station variability but encompassed a broad range of depths. Discharges calculated using thermal PIV-derived velocities were within 15% of in situ measurements when combined with depths measured directly in the field or estimated from field spectra and within 40% when the depth information also was derived from thermal images. The results of this initial, proof-of-concept investigation suggest that remote sensing techniques could facilitate measurement of river discharge.

High-mode-number ballooning modes in a heliotron/torsatron system: 1, Local magnetic shear

International Nuclear Information System (INIS)

Nakajima, N.

1996-05-01

The characteristics of the local magnetic shear, a quantity associated with high-mode-number ballooning mode stability, are considered in heliotron/torsatron devices that have a large Shafranov shift. The local magnetic shear is shown to vanish even in the stellarator-like region in which the global magnetic shear is positive. The reason for this is that the degree of the local compression of the poloidal magnetic field on the outer side of the torus, which maintains the toroidal force balance, is reduced in the stellarator-like region of global magnetic shear because the global rotational transform in heliotron/torsatron systems is a radially increasing function. This vanishing of the local magnetic shear is a universal property in heliotron/torsatron systems with a large Shafranov shift since it results from toroidal force balance in the stellarator-like global shear regime that is inherent to such systems

FPGA based high-performance multi-channel analyzer with local histogram memory

International Nuclear Information System (INIS)

Kulkarni, C.P.; Vaidya, P.P.; Paulson, M.

2004-01-01

Modern nuclear spectroscopy systems demand for a Multi-Channel Analyzer (MCA) with higher resolution, faster speed and other advanced features. The MCA described here is targeted for such demanding applications. The MCA has an in-built local histogram memory and a memory management unit integrated in an FPGA (Field Programmable Gate Array) chip. In addition to the integrated low power digital circuitry, the system utilizes state of the art advanced analog circuits like low power, high speed and high precision comparators, op-amps, ADC and DAC. The operating resolution is selectable from 256 channels to 16384 channels for pulse height analysis. It supports high count rate applications (typically 100 KHz) without significant dead time penalty. It can have an USB bus interface with simple changes. In general, the MCA gives a high performance, compact and low power alternative for portable and battery operated systems as well as for high end laboratory instruments. (author)

High speed fiber optics local area networks: Design and implementation

Science.gov (United States)

Tobagi, Fouad A.

1988-01-01

The design of high speed local area networks (HSLAN) for communication among distributed devices requires solving problems in three areas: (1) the network medium and its topology; (2) the medium access control; and (3) the network interface. Considerable progress has been made in all areas. Accomplishments are divided into two groups according to their theoretical or experimental nature. A brief summary is given in Section 2, including references to papers which appeared in the literature, as well as to Ph.D. dissertations and technical reports published at Stanford University.

Highly Localized Acoustic Streaming and Size-Selective Submicrometer Particle Concentration Using High Frequency Microscale Focused Acoustic Fields.

Science.gov (United States)

Collins, David J; Ma, Zhichao; Ai, Ye

2016-05-17

Concentration and separation of particles and biological specimens are fundamental functions of micro/nanofluidic systems. Acoustic streaming is an effective and biocompatible way to create rapid microscale fluid motion and induce particle capture, though the >100 MHz frequencies required to directly generate acoustic body forces on the microscale have traditionally been difficult to generate and localize in a way that is amenable to efficient generation of streaming. Moreover, acoustic, hydrodynamic, and electrical forces as typically applied have difficulty manipulating specimens in the submicrometer regime. In this work, we introduce highly focused traveling surface acoustic waves (SAW) at high frequencies between 193 and 636 MHz for efficient and highly localized production of acoustic streaming vortices on microfluidic length scales. Concentration occurs via a novel mechanism, whereby the combined acoustic radiation and streaming field results in size-selective aggregation in fluid streamlines in the vicinity of a high-amplitude acoustic beam, as opposed to previous acoustic radiation induced particle concentration where objects typically migrate toward minimum pressure locations. Though the acoustic streaming is induced by a traveling wave, we are able to manipulate particles an order of magnitude smaller than possible using the traveling wave force alone. We experimentally and theoretically examine the range of particle sizes that can be captured in fluid streamlines using this technique, with rapid particle concentration demonstrated down to 300 nm diameters. We also demonstrate that locations of trapping and concentration are size-dependent, which is attributed to the combined effects of the acoustic streaming and acoustic forces.

Combined local current distribution measurements and high resolution neutron radiography of operating direct methanol fuel cells

Energy Technology Data Exchange (ETDEWEB)

Schroeder, Alexander; Wippermann, Klaus [Forschungszentrum Juelich GmbH (Germany). Inst. of Energy Research, IEF-3: Fuel Cells; Sanders, Tilman [RWTH Aachen (DE). Inst. for Power Electronics and Electrical Drives (ISEA); Arlt, Tobias [Helmholtz Centre Berlin (Germany). Inst. for Applied Materials

2010-07-01

Neutron radiography allows the investigation of the local fluid distribution in direct methanol fuel cells (DMFCs) under operating conditions. Spatial resolutions in the order of some tens of micrometers at the full test cell area are achieved. This offers the possibility to study practice-oriented, large stack cells with an active area of several hundred cm{sup 2} as well as specially designed, small test cells with an area of some cm{sup 2}. Combined studies of high resolution neutron radiography and segmented cell measurements are especially valuable, because they enable a correlation of local fluid distribution and local performance [1, 2]. The knowledge of this interdependency is essential to optimise the water management and performance respecting a homogeneous fluid, current and temperature distribution and to achieve high performance and durability of DMFCs. (orig.)

Innovative Technique for High-Accuracy Remote Monitoring of Surface Water

Science.gov (United States)

Gisler, A.; Barton-Grimley, R. A.; Thayer, J. P.; Crowley, G.

2016-12-01

Lidar (light detection and ranging) provides absolute depth and topographic mapping capability compared to other remote sensing methods, which is useful for mapping rapidly changing environments such as riverine systems and agricultural waterways. Effectiveness of current lidar bathymetric systems is limited by the difficulty in unambiguously identifying backscattered lidar signals from the water surface versus the bottom, limiting their depth resolution to 0.3-0.5 m. Additionally these are large, bulky systems that are constrained to expensive aircraft-mounted platforms and use waveform-processing techniques requiring substantial computation time. These restrictions are prohibitive for many potential users. A novel lidar device has been developed that allows for non-contact measurements of water depth down to 1 cm with an accuracy and precision of shallow to deep water allowing for shoreline charting, measuring water volume, mapping bottom topology, and identifying submerged objects. The scalability of the technique opens up the ability for handheld or UAS-mounted lidar bathymetric systems, which provides for potential applications currently unavailable to the community. The high laser pulse repetition rate allows for very fine horizontal resolution while the photon-counting technique permits real-time depth measurement and object detection. The enhanced measurement capability, portability, scalability, and relatively low-cost creates the opportunity to perform frequent high-accuracy monitoring and measuring of aquatic environments which is crucial for monitoring water resources on fast timescales. Results from recent campaigns measuring water depth in flowing creeks and murky ponds will be presented which demonstrate that the method is not limited by rough water surfaces and can map underwater topology through moderately turbid water.

Homogenization of a locally-periodic medium with areas of low and high diffusivity

NARCIS (Netherlands)

Noorden, van T.L.; Muntean, A.

2010-01-01

We aim at understanding transport in porous materials including regions with both high and low diffusivities. For such scenarios, the transport becomes structured (here: micro- macro). The geometry we have in mind includes regions of low diffusivity arranged in a locally-periodic fashion. We choose

Modeling the Subjective Quality of Highly Contrasted Videos Displayed on LCD With Local Backlight Dimming

DEFF Research Database (Denmark)

Mantel, Claire; Bech, Søren; Korhonen, Jari

2015-01-01

Local backlight dimming is a technology aiming at both saving energy and improving visual quality on television sets. As the rendition of the image is specified locally, the numerical signal corresponding to the displayed image needs to be computed through a model of the display. This simulated...... signal can then be used as input to objective quality metrics. The focus of this paper is on determining which characteristics of locally backlit displays influence quality assessment. A subjective experiment assessing the quality of highly contrasted videos displayed with various local backlight......-dimming algorithms is set up. Subjective results are then compared with both objective measures and objective quality metrics using different display models. The first analysis indicates that the most significant objective features are temporal variations, power consumption (probably representing leakage...

Mode decomposition methods for flows in high-contrast porous media. Global-local approach

KAUST Repository

Ghommem, Mehdi; Presho, Michael; Calo, Victor M.; Efendiev, Yalchin R.

2013-01-01

In this paper, we combine concepts of the generalized multiscale finite element method (GMsFEM) and mode decomposition methods to construct a robust global-local approach for model reduction of flows in high-contrast porous media. This is achieved by implementing Proper Orthogonal Decomposition (POD) and Dynamic Mode Decomposition (DMD) techniques on a coarse grid computed using GMsFEM. The resulting reduced-order approach enables a significant reduction in the flow problem size while accurately capturing the behavior of fully-resolved solutions. We consider a variety of high-contrast coefficients and present the corresponding numerical results to illustrate the effectiveness of the proposed technique. This paper is a continuation of our work presented in Ghommem et al. (2013) [1] where we examine the applicability of POD and DMD to derive simplified and reliable representations of flows in high-contrast porous media on fully resolved models. In the current paper, we discuss how these global model reduction approaches can be combined with local techniques to speed-up the simulations. The speed-up is due to inexpensive, while sufficiently accurate, computations of global snapshots. © 2013 Elsevier Inc.

Mode decomposition methods for flows in high-contrast porous media. Global-local approach

KAUST Repository

Ghommem, Mehdi

2013-11-01

In this paper, we combine concepts of the generalized multiscale finite element method (GMsFEM) and mode decomposition methods to construct a robust global-local approach for model reduction of flows in high-contrast porous media. This is achieved by implementing Proper Orthogonal Decomposition (POD) and Dynamic Mode Decomposition (DMD) techniques on a coarse grid computed using GMsFEM. The resulting reduced-order approach enables a significant reduction in the flow problem size while accurately capturing the behavior of fully-resolved solutions. We consider a variety of high-contrast coefficients and present the corresponding numerical results to illustrate the effectiveness of the proposed technique. This paper is a continuation of our work presented in Ghommem et al. (2013) [1] where we examine the applicability of POD and DMD to derive simplified and reliable representations of flows in high-contrast porous media on fully resolved models. In the current paper, we discuss how these global model reduction approaches can be combined with local techniques to speed-up the simulations. The speed-up is due to inexpensive, while sufficiently accurate, computations of global snapshots. © 2013 Elsevier Inc.

A UNIVERSAL, LOCAL STAR FORMATION LAW IN GALACTIC CLOUDS, NEARBY GALAXIES, HIGH-REDSHIFT DISKS, AND STARBURSTS

International Nuclear Information System (INIS)

Krumholz, Mark R.; Dekel, Avishai; McKee, Christopher F.

2012-01-01

Star formation laws are rules that relate the rate of star formation in a particular region, either an entire galaxy or some portion of it, to the properties of the gas, or other galactic properties, in that region. While observations of Local Group galaxies show a very simple, local star formation law in which the star formation rate per unit area in each patch of a galaxy scales linearly with the molecular gas surface density in that patch, recent observations of both Milky Way molecular clouds and high-redshift galaxies apparently show a more complicated relationship in which regions of equal molecular gas surface density can form stars at quite different rates. These data have been interpreted as implying either that different star formation laws may apply in different circumstances, that the star formation law is sensitive to large-scale galaxy properties rather than local properties, or that there are high-density thresholds for star formation. Here we collate observations of the relationship between gas and star formation rate from resolved observations of Milky Way molecular clouds, from kpc-scale observations of Local Group galaxies, and from unresolved observations of both disk and starburst galaxies in the local universe and at high redshift. We show that all of these data are in fact consistent with a simple, local, volumetric star formation law. The apparent variations stem from the fact that the observed objects have a wide variety of three-dimensional size scales and degrees of internal clumping, so even at fixed gas column density the regions being observed can have wildly varying volume densities. We provide a simple theoretical framework to remove this projection effect, and we use it to show that all the data, from small solar neighborhood clouds with masses ∼10 3 M ☉ to submillimeter galaxies with masses ∼10 11 M ☉ , fall on a single star formation law in which the star formation rate is simply ∼1% of the molecular gas mass per local

Local nuclear slope and curvature in high energy pp and pp-bar elastic scattering

Energy Technology Data Exchange (ETDEWEB)

Desgrolard, P. [Lyon-1 Univ., 69 - Villeurbanne (France). Inst. de Physique Nucleaire; Kontros, J.; Lengyel, A.I. [Inst. of Electron Physics, Uzhgorod (Ukraine); Martynov, E.S. [National Academy of Sciences of Ukraine, Kiev (Ukraine). Bogolyubov Inst. for Theoretical Physics

1997-05-01

The local nuclear slope is reconstructed from the experimental angular distributions with a procedure that uses overlapping t-bins, for an energy that ranges from the ISR to the Sp-bar pS and the Tevatron. Predictions of several models of (p-bar,p) elastic scattering at high energy are tested. Only a model with two-components Pomeron and Odderon gives a satisfactory agreement with the (non fitted) slope data. The extreme sensitivity of the local nuclear curvature with the choice for a Pomeron model is emphasized. (author). 30 refs.

Obtaining highly excited eigenstates of the localized XX chain via DMRG-X

Science.gov (United States)

Devakul, Trithep; Khemani, Vedika; Pollmann, Frank; Huse, David A.; Sondhi, S. L.

2017-10-01

We benchmark a variant of the recently introduced density matrix renormalization group (DMRG)-X algorithm against exact results for the localized random field XX chain. We find that the eigenstates obtained via DMRG-X exhibit a highly accurate l-bit description for system sizes much bigger than the direct, many-body, exact diagonalization in the spin variables is able to access. We take advantage of the underlying free fermion description of the XX model to accurately test the strengths and limitations of this algorithm for large system sizes. We discuss the theoretical constraints on the performance of the algorithm from the entanglement properties of the eigenstates, and its actual performance at different values of disorder. A small but significant improvement to the algorithm is also presented, which helps significantly with convergence. We find that, at high entanglement, DMRG-X shows a bias towards eigenstates with low entanglement, but can be improved with increased bond dimension. This result suggests that one must be careful when applying the algorithm for interacting many-body localized spin models near a transition. This article is part of the themed issue 'Breakdown of ergodicity in quantum systems: from solids to synthetic matter'.

New evidence of Yangtze delta recession after closing of the Three Gorges Dam

Science.gov (United States)

Luo, X. X.; Yang, S. L.; Wang, R. S.; Zhang, C. Y.; Li, P.

2017-01-01

Many deltas are likely undergoing net erosion because of rapid decreases in riverine sediment supply and rising global sea levels. However, detecting erosion in subaqueous deltas is usually difficult because of the lack of bathymetric data. In this study, by comparing bathymetric data between 1981 and 2012 and surficial sediment grain sizes from the Yangtze subaqueous delta front over the last three decades, we found severe erosion and significant sediment coarsening in recent years since the construction of Three Gorges Dam (TGD), the largest dam in the world. We attributed these morphological and sedimentary variations mainly to the human-induced drastic decline of river sediment discharge. Combined with previous studies based on bathymetric data from different areas of the same delta, we theorize that the Yangtze subaqueous delta is experiencing overall (net) erosion, although local accumulation was also noted. We expect that the Yangtze sediment discharge will further decrease in the near future because of construction of new dams and delta recession will continue to occur. PMID:28145520

Effects of sea level rise, land subsidence, bathymetric change and typhoon tracks on storm flooding in the coastal areas of Shanghai.

Science.gov (United States)

Wang, Jun; Yi, Si; Li, Mengya; Wang, Lei; Song, Chengcheng

2018-04-15

We compared the effects of three key environmental factors of coastal flooding: sea level rise (SLR), land subsidence (LS) and bathymetric change (BC) in the coastal areas of Shanghai. We use the hydrological simulation model MIKE 21 to simulate flood magnitudes under multiple scenarios created from combinations of the key environmental factors projected to year 2030 and 2050. Historical typhoons (TC9711, TC8114, TC0012, TC0205 and TC1109), which caused extremely high surges and considerable losses, were selected as reference tracks to generate potential typhoon events that would make landfalls in Shanghai (SHLD), in the north of Zhejiang (ZNLD) and moving northwards in the offshore area of Shanghai (MNS) under those scenarios. The model results provided assessment of impact of single and compound effects of the three factors (SLR, LS and BC) on coastal flooding in Shanghai for the next few decades. Model simulation showed that by the year 2030, the magnitude of storm flooding will increase due to the environmental changes defined by SLR, LS, and BC. Particularly, the compound scenario of the three factors will generate coastal floods that are 3.1, 2.7, and 1.9 times greater than the single factor change scenarios by, respectively, SLR, LS, and BC. Even more drastically, in 2050, the compound impact of the three factors would be 8.5, 7.5, and 23.4 times of the single factors. It indicates that the impact of environmental changes is not simple addition of the effects from individual factors, but rather multiple times greater of that when the projection time is longer. We also found for short-term scenarios, the bathymetry change is the most important factor for the changes in coastal flooding; and for long-term scenarios, sea level rise and land subsidence are the major factors that coastal flood prevention and management should address. Copyright © 2017 Elsevier B.V. All rights reserved.

Local injection of high-molecular hyaluronan promotes wound healing in old rats by increasing angiogenesis.

Science.gov (United States)

Huang, Luying; Wang, Yi; Liu, Hua; Huang, Jianhua

2018-02-02

Impaired angiogenesis contributes to delayed wound healing in aging. Hyaluronan (HA) has a close relationship with angiogenesis and wound healing. However, HA content decreases with age. In this study, we used high molecular weight HA (HMW-HA) (1650 kDa), and investigated its effects on wound healing in old rats by local injection. We found that HMW-HA significantly increases proliferation, migration and tube formation in endothelial cells, and protects endothelial cells against apoptosis. Local injection of HMW-HA promotes wound healing by increasing angiogenesis in old rats. HMW-HA increases the phosphorylation of Src, ERK and AKT, leading to increased angiogenesis, suggesting that local injection of HMW-HA promotes wound healing in elderly patients.

Percutaneous nephrolithotripsy under assisted local anaesthesia for high risk patients: Is it effective?

Directory of Open Access Journals (Sweden)

T.KH. Fathelbab

2013-12-01

Conclusion: Our results demonstrated that PNL under local anesthesia with narcotics and sedatives seems to be a satisfying solution for the treatment of a selected group of patients with renal pelvic stones and who have high anesthetic risk. However, additional studies with different groups of patients are required to validate our results.

Adjuvant chemoradiotherapy instead of revision radical resection after local excision for high-risk early rectal cancer.

Science.gov (United States)

Jeong, Jae-Uk; Nam, Taek-Keun; Kim, Hyeong-Rok; Shim, Hyun-Jeong; Kim, Yong-Hyub; Yoon, Mee Sun; Song, Ju-Young; Ahn, Sung-Ja; Chung, Woong-Ki

2016-09-05

After local excision of early rectal cancer, revision radical resection is recommended for patients with high-risk pathologic stage T1 (pT1) or pT2 cancer, but the revision procedure has high morbidity rates. We evaluated the efficacy of adjuvant concurrent chemoradiotherapy (CCRT) for reducing recurrence after local excision in these patients. Eighty-three patients with high-risk pT1 or pT2 rectal cancer underwent postoperative adjuvant CCRT after local excision. We defined high-risk features as pT1 having tumor size ≤3 cm, and/or resection margin (RM) ≤3 mm, and/or lymphovascular invasion (LVI), and/or non-full thickness excision such as endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD), or unknown records regarding those features, or pT2 cancer. Radiotherapy was administered with a median dose of 50.4 Gy in 1.8 Gy fraction size over 5-7 weeks. Concurrent 5-fluorouracil and leucovorin were administered for 4 days in the first and fifth weeks of radiotherapy. The median interval between local excision and radiotherapy was 34 (range, 11-104) days. Fifteen patients (18.1 %) had stage pT2 tumors, 22 (26.5 %) had RM of ≥3 mm, and 21 (25.3 %) had tumors of ≥3 cm in size. Thirteen patients (15.7 %) had LVI. Transanal excision was performed in 58 patients (69.9 %) and 25 patients (30.1 %) underwent EMR or ESD. The median follow-up was 61 months. The 5-year overall survival (OS), locoregional relapse-free survival (LRFS), and disease-free survival (DFS) rates for all patients were 94.9, 91.0, and 89.8 %, respectively. Multivariate analysis did not identify any significant factors for OS or LRFS, but the only significant factor affecting DFS was the pT stage (p = 0.027). In patients with high-risk pT1 rectal cancer, adjuvant CCRT after local excision could be an effective alternative treatment instead of revision radical resection. However, patients with pT2 stage showed inferior DFS compared to pT1.

Local structures of ionic liquids in the presence of gold under high pressures

Directory of Open Access Journals (Sweden)

Hai-Chou Chang

2013-03-01

Full Text Available The interactions between ionic liquid ([EMI][TFS] and gold surfaces have been investigated via the application of pressures up to ca. 2 GPa. Comparing the spectral features of [EMI][TFS]/gold with those of pure [EMI][TFS], no appreciable changes of C-H bands in the presence of gold powders were observed under ambient pressure. Nevertheless, the imidazolium C-H bands display red shifts in frequency as the [EMI][TFS] / Au mixture was compressed to the pressure above 1.4 GPa and a new alkyl C-H band at ca. 3016 cm−1 was also revealed. These spectral changes, being related to the addition of gold powders and pressure elevation, should be attributed to the local structural changes of C-H groups caused by pressure-enhanced interfacial interactions between [EMI][TFS] and Au. Gold powders tend to induce the changes in hydrogen bonding structures of imidazolium C2-H group under high pressures. The pressure-dependent spectral features in the asymmetric SO3 stretching region display band-narrowing and minor local structural changes induced by the presence of gold particles under high pressures. These observations suggest that Au powders perturb structural equilibrium of C-H groups of cations under high pressures.

High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3

Energy Technology Data Exchange (ETDEWEB)

Malinouski, M.; Kehr, S.; Finney, L.; Vogt, S.; Carlson, B.A.; Seravalli, J.; Jin, R.; Handy, D.E.; Park, T.J.; Loscalzo, J.; Hatfield, D.L.; Gladyshev, V.N. (Harvard-Med)

2012-04-17

Recent advances in quantitative methods and sensitive imaging techniques of trace elements provide opportunities to uncover and explain their biological roles. In particular, the distribution of selenium in tissues and cells under both physiological and pathological conditions remains unknown. In this work, we applied high-resolution synchrotron X-ray fluorescence microscopy (XFM) to map selenium distribution in mouse liver and kidney. Liver showed a uniform selenium distribution that was dependent on selenocysteine tRNA{sup [Ser]Sec} and dietary selenium. In contrast, kidney selenium had both uniformly distributed and highly localized components, the latter visualized as thin circular structures surrounding proximal tubules. Other parts of the kidney, such as glomeruli and distal tubules, only manifested the uniformly distributed selenium pattern that co-localized with sulfur. We found that proximal tubule selenium localized to the basement membrane. It was preserved in Selenoprotein P knockout mice, but was completely eliminated in glutathione peroxidase 3 (GPx3) knockout mice, indicating that this selenium represented GPx3. We further imaged kidneys of another model organism, the naked mole rat, which showed a diminished uniformly distributed selenium pool, but preserved the circular proximal tubule signal. We applied XFM to image selenium in mammalian tissues and identified a highly localized pool of this trace element at the basement membrane of kidneys that was associated with GPx3. XFM allowed us to define and explain the tissue topography of selenium in mammalian kidneys at submicron resolution.

Local regression type methods applied to the study of geophysics and high frequency financial data

Science.gov (United States)

Mariani, M. C.; Basu, K.

2014-09-01

In this work we applied locally weighted scatterplot smoothing techniques (Lowess/Loess) to Geophysical and high frequency financial data. We first analyze and apply this technique to the California earthquake geological data. A spatial analysis was performed to show that the estimation of the earthquake magnitude at a fixed location is very accurate up to the relative error of 0.01%. We also applied the same method to a high frequency data set arising in the financial sector and obtained similar satisfactory results. The application of this approach to the two different data sets demonstrates that the overall method is accurate and efficient, and the Lowess approach is much more desirable than the Loess method. The previous works studied the time series analysis; in this paper our local regression models perform a spatial analysis for the geophysics data providing different information. For the high frequency data, our models estimate the curve of best fit where data are dependent on time.

Local thermodynamic equilibrium in rapidly heated high energy density plasmas

International Nuclear Information System (INIS)

Aslanyan, V.; Tallents, G. J.

2014-01-01

Emission spectra and the dynamics of high energy density plasmas created by optical and Free Electron Lasers (FELs) depend on the populations of atomic levels. Calculations of plasma emission and ionization may be simplified by assuming Local Thermodynamic Equilibrium (LTE), where populations are given by the Saha-Boltzmann equation. LTE can be achieved at high densities when collisional processes are much more significant than radiative processes, but may not be valid if plasma conditions change rapidly. A collisional-radiative model has been used to calculate the times taken by carbon and iron plasmas to reach LTE at varying densities and heating rates. The effect of different energy deposition methods, as well as Ionization Potential Depression are explored. This work shows regimes in rapidly changing plasmas, such as those created by optical lasers and FELs, where the use of LTE is justified, because timescales for plasma changes are significantly longer than the times needed to achieve an LTE ionization balance

Review: Potential Strength of Fly Ash-Based Geopolymer Paste with Substitution of Local Waste Materials with High-Temperature Effect

Science.gov (United States)

Subekti, S.; Bayuaji, R.; Darmawan, M. S.; Husin, N. A.; Wibowo, B.; Anugraha, B.; Irawan, S.; Dibiantara, D.

2017-11-01

This research provided an overview of the potential fly ash based geopolymer paste for application in building construction. Geopolymer paste with various variations of fly ash substitution with local waste material and high-temperature influence exploited with the fresh and hardened condition. The local waste material which utilized for this study were sandblasting waste, carbide waste, shell powder, bagasse ash, rice husk and bottom ash. The findings of this study indicated that fly-based geopolymer paste with local waste material substitution which had high-temperature influence ash showed a similar nature of OPC binders potentially used in civil engineering applications.

When High-Capacity Readers Slow Down and Low-Capacity Readers Speed Up: Working Memory and Locality Effects.

Science.gov (United States)

Nicenboim, Bruno; Logačev, Pavel; Gattei, Carolina; Vasishth, Shravan

2016-01-01

We examined the effects of argument-head distance in SVO and SOV languages (Spanish and German), while taking into account readers' working memory capacity and controlling for expectation (Levy, 2008) and other factors. We predicted only locality effects, that is, a slowdown produced by increased dependency distance (Gibson, 2000; Lewis and Vasishth, 2005). Furthermore, we expected stronger locality effects for readers with low working memory capacity. Contrary to our predictions, low-capacity readers showed faster reading with increased distance, while high-capacity readers showed locality effects. We suggest that while the locality effects are compatible with memory-based explanations, the speedup of low-capacity readers can be explained by an increased probability of retrieval failure. We present a computational model based on ACT-R built under the previous assumptions, which is able to give a qualitative account for the present data and can be tested in future research. Our results suggest that in some cases, interpreting longer RTs as indexing increased processing difficulty and shorter RTs as facilitation may be too simplistic: The same increase in processing difficulty may lead to slowdowns in high-capacity readers and speedups in low-capacity ones. Ignoring individual level capacity differences when investigating locality effects may lead to misleading conclusions.

When high-capacity readers slow down and low-capacity readers speed up: Working memory and locality effects

Directory of Open Access Journals (Sweden)

Bruno eNicenboim

2016-03-01

Full Text Available We examined the effects of argument-head distance in SVO and SOV languages (Spanish and German, while taking into account readers’ working memory capacity and controlling for expectation (Levy, 2008 and other factors. We predicted only locality effects, that is, a slow-down produced by increased dependency distance (Gibson, 2000; Lewis & Vasishth, 2005. Furthermore, we expected stronger locality effects for readers with low working memory capacity. Contrary to our predictions, low-capacity readers showed faster reading with increased distance, while high-capacity readers showed locality effects. We suggest that while the locality effects are compatible with memory-based explanations, the speedup of low-capacity readers can be explained by an increased probability of retrieval failure. We present a computational model based on ACT-R built under the previous assumptions, which is able to give a qualitative account for the present data and can be tested in future research. Our results suggest that in some cases, interpreting longer RTs as indexing increased processing difficulty and shorter RTs as facilitation may be too simplistic: The same increase in processing difficulty may lead to slowdowns in high-capacity readers and speedups in low-capacity ones. Ignoring individual level capacity differences when investigating locality effects may lead to misleading conclusions.

Local Electric Field Facilitates High-Performance Li-Ion Batteries.

Science.gov (United States)

Liu, Youwen; Zhou, Tengfei; Zheng, Yang; He, Zhihai; Xiao, Chong; Pang, Wei Kong; Tong, Wei; Zou, Youming; Pan, Bicai; Guo, Zaiping; Xie, Yi

2017-08-22

By scrutinizing the energy storage process in Li-ion batteries, tuning Li-ion migration behavior by atomic level tailoring will unlock great potential for pursuing higher electrochemical performance. Vacancy, which can effectively modulate the electrical ordering on the nanoscale, even in tiny concentrations, will provide tempting opportunities for manipulating Li-ion migratory behavior. Herein, taking CuGeO 3 as a model, oxygen vacancies obtained by reducing the thickness dimension down to the atomic scale are introduced in this work. As the Li-ion storage progresses, the imbalanced charge distribution emerging around the oxygen vacancies could induce a local built-in electric field, which will accelerate the ions' migration rate by Coulomb forces and thus have benefits for high-rate performance. Furthermore, the thus-obtained CuGeO 3 ultrathin nanosheets (CGOUNs)/graphene van der Waals heterojunctions are used as anodes in Li-ion batteries, which deliver a reversible specific capacity of 1295 mAh g -1 at 100 mA g -1 , with improved rate capability and cycling performance compared to their bulk counterpart. Our findings build a clear connection between the atomic/defect/electronic structure and intrinsic properties for designing high-efficiency electrode materials.

A high energy microscope for local strain measurements within bulk materials

DEFF Research Database (Denmark)

Lienert, U.; Poulsen, H.F.; Martins, R.V.

2000-01-01

A novel diffraction technique for local, three dimensional strain scanning within bulk materials is presented. The technique utilizes high energy, micro-focussed synchrotron radiation which can penetrate several millimeters into typical metals. The spatial resolution can be as narrow as 1 mum...... in one dimension and in three dimensions about 5x10x100 mum(3) Bulk properties are probed non-destructively and in-situ measurements during thermo-mechanical processing are feasible. A dedicated experimental station has been constructed at the ID11 beamline of the European Synchrotron Radiation Facility...

Feature Extraction Method for High Impedance Ground Fault Localization in Radial Power Distribution Networks

DEFF Research Database (Denmark)

Jensen, Kåre Jean; Munk, Steen M.; Sørensen, John Aasted

1998-01-01

A new approach to the localization of high impedance ground faults in compensated radial power distribution networks is presented. The total size of such networks is often very large and a major part of the monitoring of these is carried out manually. The increasing complexity of industrial...... of three phase voltages and currents. The method consists of a feature extractor, based on a grid description of the feeder by impulse responses, and a neural network for ground fault localization. The emphasis of this paper is the feature extractor, and the detection of the time instance of a ground fault...... processes and communication systems lead to demands for improved monitoring of power distribution networks so that the quality of power delivery can be kept at a controlled level. The ground fault localization method for each feeder in a network is based on the centralized frequency broadband measurement...

Host-specificity among abundant and rare taxa in the sponge microbiome.

Science.gov (United States)

Reveillaud, Julie; Maignien, Loïs; Murat Eren, A; Huber, Julie A; Apprill, Amy; Sogin, Mitchell L; Vanreusel, Ann

2014-06-01

Microbial communities have a key role in the physiology of the sponge host, and it is therefore essential to understand the stability and specificity of sponge-symbiont associations. Host-specific bacterial associations spanning large geographic distance are widely acknowledged in sponges. However, the full spectrum of specificity remains unclear. In particular, it is not known whether closely related sponges host similar or very different microbiota over wide bathymetric and geographic gradients, and whether specific associations extend to the rare members of the sponge microbiome. Using the ultra-deep Illumina sequencing technology, we conducted a comparison of sponge bacterial communities in seven closely related Hexadella species with a well-resolved host phylogeny, as well as of a distantly related sponge Mycale. These samples spanned unprecedentedly large bathymetric (15-960 m) gradients and varying European locations. In addition, this study included a bacterial community analysis of the local background seawater for both Mycale and the widespread deep-sea taxa Hexadella cf. dedritifera. We observed a striking diversity of microbes associated with the sponges, spanning 47 bacterial phyla. The data did not reveal any Hexadella microbiota co-speciation pattern, but confirmed sponge-specific and species-specific host-bacteria associations, even within extremely low abundant taxa. Oligotyping analysis also revealed differential enrichment preferences of closely related Nitrospira members in closely related sponges species. Overall, these results demonstrate highly diverse, remarkably specific and stable sponge-bacteria associations that extend to members of the rare biosphere at a very fine phylogenetic scale, over significant geographic and bathymetric gradients.

103PD brachytherapy and external beam irradiation for clinically localized, high-risk prostatic carcinoma

International Nuclear Information System (INIS)

Dattoli, Michael; Wallner, Kent; Sorace, Richard; Koval, John; Cash, Jennifer; Acosta, Rudolph; Brown, Charles; Etheridge, James; Binder, Michael; Brunelle, Richard; Kirwan, Novelle; Sanchez, Servando; Stein, Douglas; Wasserman, Stuart

1996-01-01

Purpose: To summarize biochemical failure rates and morbidity of external beam irradiation (EBRT) combined with palladium ( 103 Pd) boost for clinically localized high-risk prostate carcinoma. Methods and Materials: Seventy-three consecutive patients with stage T2a-T3 prostatic carcinoma were treated from 1991 through 1994. Each patient had at least one of the following risk factors for extracapsular disease extension: Stage T2b or greater (71 patients), Gleason score 7-10 (40 patients), prostate specific antigen (PSA) >15 (32 patients), or elevated prostatic acid phosphatase (PAP) (17 patients). Patients received 41 Gy EBRT to a limited pelvic field, followed 4 weeks later by a 103 Pd boost (prescription dose: 80 Gy). Biochemical failure was defined as a PSA greater than 1.0 ng/ml (normal 103 Pd brachytherapy for clinically localized, high-risk prostate cancer compare favorably with that reported after conventional dose EBRT alone. Morbidity has been acceptable

High-Resolution Imaging of Selenium in Kidneys: A Localized Selenium Pool Associated with Glutathione Peroxidase 3

Science.gov (United States)

Malinouski, Mikalai; Kehr, Sebastian; Finney, Lydia; Vogt, Stefan; Carlson, Bradley A.; Seravalli, Javier; Jin, Richard; Handy, Diane E.; Park, Thomas J.; Loscalzo, Joseph; Hatfield, Dolph L.

2012-01-01

Abstract Aim: Recent advances in quantitative methods and sensitive imaging techniques of trace elements provide opportunities to uncover and explain their biological roles. In particular, the distribution of selenium in tissues and cells under both physiological and pathological conditions remains unknown. In this work, we applied high-resolution synchrotron X-ray fluorescence microscopy (XFM) to map selenium distribution in mouse liver and kidney. Results: Liver showed a uniform selenium distribution that was dependent on selenocysteine tRNA[Ser]Sec and dietary selenium. In contrast, kidney selenium had both uniformly distributed and highly localized components, the latter visualized as thin circular structures surrounding proximal tubules. Other parts of the kidney, such as glomeruli and distal tubules, only manifested the uniformly distributed selenium pattern that co-localized with sulfur. We found that proximal tubule selenium localized to the basement membrane. It was preserved in Selenoprotein P knockout mice, but was completely eliminated in glutathione peroxidase 3 (GPx3) knockout mice, indicating that this selenium represented GPx3. We further imaged kidneys of another model organism, the naked mole rat, which showed a diminished uniformly distributed selenium pool, but preserved the circular proximal tubule signal. Innovation: We applied XFM to image selenium in mammalian tissues and identified a highly localized pool of this trace element at the basement membrane of kidneys that was associated with GPx3. Conclusion: XFM allowed us to define and explain the tissue topography of selenium in mammalian kidneys at submicron resolution. Antioxid. Redox Signal. 16, 185–192. PMID:21854231

Morphology and sedimentology of the Itaipú Embayment - Niterói/RJ

Directory of Open Access Journals (Sweden)

SALVADOR MARCUS VINICIUS S.

2002-01-01

Full Text Available Bathymetric and sedimentological data from water depths between 3 and 28 meters are the basis of a detailed bathymetric map of the Itaipú Embayment and an understanding of its sedimentary dynamics. Shallower than 16 meters the contours are parallel to the shoreline whereas the morphology of the deeper bottom is influenced by the Menina, Mãe, and Pai islands. Medium sand is prevalent, with local variations in more protected or less protected areas. Minor amount of black mud possibly derives from the Itaipú Lagoon. Siliciclastic granules and pebbles may be relict. The Itaipú Embayment's bottom morphology is controlled by stormy waves and the calmer easternmost part of the embayment presents a tendency to accumulate finer sediments.

Highly tunable local gate controlled complementary graphene device performing as inverter and voltage controlled resistor.

Science.gov (United States)

Kim, Wonjae; Riikonen, Juha; Li, Changfeng; Chen, Ya; Lipsanen, Harri

2013-10-04

Using single-layer CVD graphene, a complementary field effect transistor (FET) device is fabricated on the top of separated back-gates. The local back-gate control of the transistors, which operate with low bias at room temperature, enables highly tunable device characteristics due to separate control over electrostatic doping of the channels. Local back-gating allows control of the doping level independently of the supply voltage, which enables device operation with very low VDD. Controllable characteristics also allow the compensation of variation in the unintentional doping typically observed in CVD graphene. Moreover, both p-n and n-p configurations of FETs can be achieved by electrostatic doping using the local back-gate. Therefore, the device operation can also be switched from inverter to voltage controlled resistor, opening new possibilities in using graphene in logic circuitry.

Transmicrocatheter local injection of ethanol to treat hepatocellular carcinoma with high flow arteriovenous shunts

International Nuclear Information System (INIS)

Guan Shouhai; Shan Hong; Jiang Zaibo; Huang Mingsheng; Zhu Kangshun; Li Zhengran; Meng Xiaochun

2002-01-01

Objective: To evaluate the feasibility and clinical effect of embolization therapy in treating the high flow hepatic arteriovenous shunts in hepatocellular carcinoma (HCC) by locally injected ethanol through microcatheter. Methods: Forty-one branches of arteriovenous shunts were treated by local ethanol infusion through microcatheter in 29 patients suffered with HCC. Angiography was performed to observe the embolization effect and influence to non-targeted vessels. Result: Forty-one branches of arteriovenous shunts in 29 patients were injected with ethanol locally. Each single shunt was infused 1-6 times. The dose of ethanol was 2-3 ml per time, and the total dose of ethanol was 2-12 ml. All shunting tracts were embolized, and all non-target vessels were protected fluently. Iodine-oil deposition was well in continued TACE. Their syndromes were improved or disappeared. Conclusion: Transmicrocatheter injection of ethanol could safely and effectively treat the hepatic arteriovenous shunts and make advantages to TACE in HCC

Atomic size and local order effects on the high temperature strength of binary Mg alloys

Energy Technology Data Exchange (ETDEWEB)

Abaspour, Saeideh, E-mail: s.abaspour78@gmail.com [ARC-Centre of Excellence for Design in Light Metals, Materials Engineering, School of Engineering, The University of Queensland, Brisbane QLD 4072 (Australia); Queensland Centre for Advanced Materials Processing and Manufacturing (AMPAM), The University of Queensland (Australia); Zambelli, Victor [ARC-Centre of Excellence for Design in Light Metals, Materials Engineering, School of Engineering, The University of Queensland, Brisbane QLD 4072 (Australia); Dargusch, Matthew [Queensland Centre for Advanced Materials Processing and Manufacturing (AMPAM), The University of Queensland (Australia); Cáceres, Carlos H. [ARC-Centre of Excellence for Design in Light Metals, Materials Engineering, School of Engineering, The University of Queensland, Brisbane QLD 4072 (Australia)

2016-09-15

The solid solution strengthening introduced by Ca (0.6 and 0.9 at%) and Sn 0.5–2.5 at%) was studied through tensile, compression and stress relaxation tests at room temperature, 373 K (100 °C) and 453 K (180 °C) on solution heat-treated and quenched specimens and compared with existing data for binary alloys containing Ca, Sn, Y, Gd, Nd, Zn and Al as well as for AZ91 alloy. At room temperature the solution-hardening rate introduced by Ca and Sn was much higher than that of Al, matching those of Y, Gd and Zn. Calcium also reduced the tension/compression asymmetry. At high temperature Ca effectively prevented stress relaxation, nearly matching Y, Gd and Nd. Tin was less effective, but still outperformed Al and AZ91 at low stresses. The effects at room and high temperature introduced by Ca and Sn appeared consistent with the presence of short-range order, in line with those introduced by Y, Nd, Gd and Zn. The larger than Mg atom size of Ca, Nd, Gd and Y can be expected to intensify the local order by strengthening the atomic bonds through its effects on the local electron density, accounting for their greater strengthening at high temperature. For given difference in atomic size, the effects on the local order are expected to be lesser for smaller sized atoms like Sn and Zn, hence their more subdued effects.

Hybrid local piezoelectric and conductive functions for high performance airborne sound absorption

Science.gov (United States)

Rahimabady, Mojtaba; Statharas, Eleftherios Christos; Yao, Kui; Sharifzadeh Mirshekarloo, Meysam; Chen, Shuting; Tay, Francis Eng Hock

2017-12-01

A concept of hybrid local piezoelectric and electrical conductive functions for improving airborne sound absorption is proposed and demonstrated in composite foam made of porous polar polyvinylidene fluoride (PVDF) mixed with conductive single-walled carbon nanotube (SWCNT). According to our hybrid material function design, the local piezoelectric effect in the PVDF matrix with the polar structure and the electrical resistive loss of SWCNT enhanced sound energy conversion to electrical energy and subsequently to thermal energy, respectively, in addition to the other known sound absorption mechanisms in a porous material. It is found that the overall energy conversion and hence the sound absorption performance are maximized when the concentration of the SWCNT is around the conductivity percolation threshold. For the optimal composition of PVDF/5 wt. % SWCNT, a sound reduction coefficient of larger than 0.58 has been obtained, with a high sound absorption coefficient higher than 50% at 600 Hz, showing their great values for passive noise mitigation even at a low frequency.

High FDG uptake areas on pre-radiotherapy PET/CT identify preferential sites of local relapse after chemoradiotherapy for locally advanced oesophageal cancer

Energy Technology Data Exchange (ETDEWEB)

Calais, Jeremie; Lemarignier, Charles; Vera, Pierre [Henri Becquerel Cancer Center and Rouen University Hospital, Nuclear Medicine Department, Rouen (France); University of Rouen, QuantIF-LITIS (Equipe d' Accueil 4108-FR CNRS 3638), Faculty of Medicine, Rouen (France); Dubray, Bernard [University of Rouen, QuantIF-LITIS (Equipe d' Accueil 4108-FR CNRS 3638), Faculty of Medicine, Rouen (France); Centre Henri Becquerel and Rouen University Hospital, Department of Radiotherapy and Medical Physics, Rouen (France); Nkhali, Lamyaa; Thureau, Sebastien; Modzelewski, Romain; Gardin, Isabelle [Henri Becquerel Cancer Center and Rouen University Hospital, Nuclear Medicine Department, Rouen (France); University of Rouen, QuantIF-LITIS (Equipe d' Accueil 4108-FR CNRS 3638), Faculty of Medicine, Rouen (France); Centre Henri Becquerel and Rouen University Hospital, Department of Radiotherapy and Medical Physics, Rouen (France); Di Fiore, Frederic [Rouen University Hospital, Department of Gastroenterology, Rouen (France); Rouen University Hospital, Department of Oncology, Henri Becquerel Cancer Center, IRON, Rouen (France); Michel, Pierre [Rouen University Hospital, Department of Gastroenterology, Rouen (France)

2015-05-01

The high failure rates in the radiotherapy (RT) target volume suggest that patients with locally advanced oesophageal cancer (LAOC) would benefit from increased total RT doses. High 2-deoxy-2-[{sup 18}F]fluoro-D-glucose (FDG) uptake (hotspot) on pre-RT FDG positron emission tomography (PET)/CT has been reported to identify intra-tumour sites at increased risk of relapse after RT in non-small cell lung cancer and in rectal cancer. Our aim was to confirm these observations in patients with LAOC and to determine the optimal maximum standardized uptake value (SUV{sub max}) threshold to delineate smaller RT target volumes that would facilitate RT dose escalation without impaired tolerance. The study included 98 consecutive patients with LAOC treated by chemoradiotherapy (CRT). All patients underwent FDG PET/CT at initial staging and during systematic follow-up in a single institution. FDG PET/CT acquisitions were coregistered on the initial CT scan. Various subvolumes within the initial tumour (30, 40, 50, 60, 70, 80 and 90 % SUV{sub max} thresholds) and in the subsequent local recurrence (LR, 40 and 90 % SUV{sub max} thresholds) were pasted on the initial CT scan and compared[Dice, Jaccard, overlap fraction (OF), common volume/baseline volume, common volume/recurrent volume]. Thirty-five patients had LR. The initial metabolic tumour volume was significantly higher in LR tumours than in the locally controlled tumours (mean 25.4 vs 14.2 cc; p = 0.002). The subvolumes delineated on initial PET/CT with a 30-60 % SUV{sub max} threshold were in good agreement with the recurrent volume at 40 % SUV{sub max} (OF = 0.60-0.80). The subvolumes delineated on initial PET/CT with a 30-60 % SUV{sub max} threshold were in good to excellent agreement with the core volume (90 % SUV{sub max}) of the relapse (common volume/recurrent volume and OF indices 0.61-0.89). High FDG uptake on pretreatment PET/CT identifies tumour subvolumes that are at greater risk of recurrence after CRT in

Energy localization and decay in highly ionic crystals

International Nuclear Information System (INIS)

Williams, R.T.; Thoma, E.D.; Bunton, P.H.

1994-01-01

Luminescence from localized states in pure wide-gap crystals is examined from the perspective of modern fast scintillator requirements. Recent advances in the understanding of self-trapped excitons are summarized with regard to excited-state configurations, spectra, and luminescence efficiency. As an example, the fast luminescence of partially quenched type I STEs (self-trapped excitons) in RbI offers tunable-lifetime subnanosecond pulses which could be useful for timing applications. The possible role of hole localization in cross luminescence is discussed. Stokes-shifted luminescence in some pure rare-earth fluoride crystals probably originates from self-trapped excitons of forms to be discussed

Local and regional scale exchanges of dissolved organic carbon (DOC) between tidal wetlands and their adjacent coastal waters

Science.gov (United States)

Osburn, C. L.; Joshi, I.; Lebrasse, M. C.; Oviedo-Vargas, D.; Bianchi, T. S.; Bohnenstiehl, D. R.; D'Sa, E. J.; He, R.; Ko, D.; Arellano, A.; Ward, N. D.

2017-12-01

The contribution of blue carbon from tidal wetlands to the coastal ocean in the form of dissolved organic carbon (DOC) represents a terrestrial-aquatic linkage of increasing importance. DOC flux results will be presented from local (tidal creek) and regional (bays) scale studies in which various combinations of field observations, ocean-color satellite observations, and the outputs of high-resolution hydrodynamic models were used to estimate DOC export. The first project was located in Bald Head Creek, a tributary to the Cape Fear River estuary in eastern North Carolina (NC). DOC fluxes were computed using a bathymetric data collected via unmanned surface vehicle (USV) and a numerical hydrodynamic model (SCHISM) based on the relationships between colored dissolved organic matter (CDOM) absorption, DOC concentration, and salinity taken from field observations. Model predictions estimated an annual net export of DOC at 54 g C m-2 yr-1 from the tidal creek to the adjacent estuary. Carbon stable isotope (δ13C) values were used to estimate the contribution of wetland carbon to this export. In the second project, DOC fluxes from the Apalachicola Bay, FL, Barataria Bay, LA, were based on the development of algorithms between DOC and CDOM absorption derived from the VIIRS ocean color sensor. The Navy Coastal Ocean Model (NCOM) was used to compute salt flux estimates from each bay to the Louisiana-Texas shelf. The relationship between salinity and CDOM was used to estimate net annual DOC exports of 8.35 x 106 g C m-2 y-1 (Apalachicola Bay) and 7.14 x 106 g C m-2 yr-1 (Barataria Bay). These values approximate 13% and 9% of the annual loads of DOC from the Mississippi River to the Gulf of Mexico, respectively. CDOM and lignin were used in a mixing model to estimate wetland-derived DOC were 2% for Apalachicola Bay and 13% for Barataria Bay, the latter having one of the highest rates of relative sea level rise in North America. Results from our project demonstrated the utility

Local and global processing of music in high-functioning persons with autism: beyond central coherence?

Science.gov (United States)

Mottron, L; Peretz, I; Ménard, E

2000-11-01

A multi-modal abnormality in the integration of parts and whole has been proposed to account for a bias toward local stimuli in individuals with autism (Frith, 1989; Mottron & Belleville, 1993). In the current experiment, we examined the utility of hierarchical models in characterising musical information processing in autistic individuals. Participants were 13 high-functioning individuals with autism and 13 individuals of normal intelligence matched on chronological age, nonverbal IQ, and laterality, and without musical experience. The task consisted of same-different judgements of pairs of melodies. Differential local and global processing was assessed by manipulating the level, local or global, at which modifications occurred. No deficit was found in the two measures of global processing. In contrast, the clinical group performed better than the comparison group in the detection of change in nontransposed, contour-preserved melodies that tap local processing. These findings confirm the existence of a "local bias" in music perception in individuals with autism, but challenge the notion that it is accounted for by a deficit in global music processing. The present study suggests that enhanced processing of elementary physical properties of incoming stimuli, as found previously in the visual modality, may also exist in the auditory modality.

Single-stage anterior high sacrectomy for locally recurrent rectal cancer.

Science.gov (United States)

Fawaz, Khaled; Khaled, Fawaz; Smith, Myles J; Moises, Cukier; Smith, Andrew J; Yee, Albert J M

2014-03-01

A review of prospectively collected data on a consecutive series of patients undergoing single-stage anterior high sacrectomy for locally recurrent rectal carcinoma (LRRC). To determine the clinical outcome of patients who underwent anterior high sacrectomy for LRRC. High sacrectomy for oncological resection remains technically challenging. Surgery has the potential to achieve cure in carefully selected patients. Complete (R0) tumor excision in LRRC may require sacrectomy. High sacral resections (S3 and above) typically require a combined anterior/supine and posterior/prone procedure. We investigated our experience performing single-stage anterior high sacrectomy for LRRC. A consecutive series of patients with LRRC without systemic metastases who underwent resection with curative intent requiring high sacrectomy were identified. A review of a prospectively maintained colorectal and spine cancer database data was performed. An oblique dome high sacral osteotomy was performed during a single-stage anterior procedure. Outcome measures included surgical resection margin status, hospital length of stay, postoperative complications, physical functioning status, and overall survival. Nineteen consecutive patients were treated between 2002 and 2011. High sacrectomy was performed at sacral level S1-S2 in 4 patients, S2-S3 in 9 patients, and through S3 in 6 patients. An R0 resection margin was achieved histologically in all 19 cases. There was 1 early (<30 d) postoperative death (1/19, 5%). At median follow-up of 38 months, 13 patients had no evidence of residual disease, 1 was alive with disease, and 4 had died of disease. Morbidities occurred in 15 of the 19 patients (79%). Although high sacrectomy may require a combined anterior and posterior surgical approach, our series demonstrates the feasibility of performing single-stage anterior high sacrectomy in LRRC, with acceptable risks and outcomes compared with the literature. The procedure described by us for LRRC lessens

Bathymetry and capacity of Shawnee Reservoir, Oklahoma, 2016

Science.gov (United States)

Ashworth, Chad E.; Smith, S. Jerrod; Smith, Kevin A.

2017-02-13

Shawnee Reservoir (locally known as Shawnee Twin Lakes) is a man-made reservoir on South Deer Creek with a drainage area of 32.7 square miles in Pottawatomie County, Oklahoma. The reservoir consists of two lakes connected by an equilibrium channel. The southern lake (Shawnee City Lake Number 1) was impounded in 1935, and the northern lake (Shawnee City Lake Number 2) was impounded in 1960. Shawnee Reservoir serves as a municipal water supply, and water is transferred about 9 miles by gravity to a water treatment plant in Shawnee, Oklahoma. Secondary uses of the reservoir are for recreation, fish and wildlife habitat, and flood control. Shawnee Reservoir has a normal-pool elevation of 1,069.0 feet (ft) above North American Vertical Datum of 1988 (NAVD 88). The auxiliary spillway, which defines the flood-pool elevation, is at an elevation of 1,075.0 ft.The U.S. Geological Survey (USGS), in cooperation with the City of Shawnee, has operated a real-time stage (water-surface elevation) gage (USGS station 07241600) at Shawnee Reservoir since 2006. For the period of record ending in 2016, this gage recorded a maximum stage of 1,078.1 ft on May 24, 2015, and a minimum stage of 1,059.1 ft on April 10–11, 2007. This gage did not report reservoir storage prior to this report (2016) because a sufficiently detailed and thoroughly documented bathymetric (reservoir-bottom elevation) survey and corresponding stage-storage relation had not been published. A 2011 bathymetric survey with contours delineated at 5-foot intervals was published in Oklahoma Water Resources Board (2016), but that publication did not include a stage-storage relation table. The USGS, in cooperation with the City of Shawnee, performed a bathymetric survey of Shawnee Reservoir in 2016 and released the bathymetric-survey data in 2017. The purposes of the bathymetric survey were to (1) develop a detailed bathymetric map of the reservoir and (2) determine the relations between stage and reservoir storage

Unified Geomorphological Analysis Workflows with Benthic Terrain Modeler

Directory of Open Access Journals (Sweden)

Shaun Walbridge

2018-03-01

Full Text Available High resolution remotely sensed bathymetric data is rapidly increasing in volume, but analyzing this data requires a mastery of a complex toolchain of disparate software, including computing derived measurements of the environment. Bathymetric gradients play a fundamental role in energy transport through the seascape. Benthic Terrain Modeler (BTM uses bathymetric data to enable simple characterization of benthic biotic communities and geologic types, and produces a collection of key geomorphological variables known to affect marine ecosystems and processes. BTM has received continual improvements since its 2008 release; here we describe the tools and morphometrics BTM can produce, the research context which this enables, and we conclude with an example application using data from a protected reef in St. Croix, US Virgin Islands.

Maximum tumor diameter is not an independent prognostic factor in high-risk localized prostate cancer

NARCIS (Netherlands)

Oort, van I.M.; Witjes, J.A.; Kok, D.E.G.; Kiemeney, L.A.; Hulsbergen-van de Kaa, C.A.

2008-01-01

Previous studies suggest that maximum tumor diameter (MTD) is a predictor of recurrence in prostate cancer (PC). This study investigates the prognostic value of MTD for biochemical recurrence (BCR) in patients with PC, after radical prostatectomy (RP), with emphasis on high-risk localized prostate

Potentials of high resolution magnetic resonance imaging versus computed tomography for preoperative local staging of colon cancer

International Nuclear Information System (INIS)

Rollven, Erik; Blomqvist, Lennart; Holm, Torbjorn; Glimelius, Bengt; Loerinc, Esther

2013-01-01

Background: Preoperative identification of locally advanced colon cancer is of importance in order to properly plan treatment. Purpose: To study high resolution T2-weighted magnetic resonance imaging (MRI) versus computed tomography (CT) for preoperative staging of colon cancer with surgery and histopathology as reference standard. Material and Methods: Twenty-eight patients with a total of 29 tumors were included. Patients were examined on a 1.5 T MR unit using a phased array body coil. T2 turbo spin-echo high resolution sequences were obtained in a coronal, transverse, and perpendicular plane to the long axis of the colon at the site of the tumor. Contrast-enhanced CT was performed using a protocol for metastasis staging. The examinations were independently evaluated by two gastrointestinal radiologists using criteria adapted to imaging for prediction of T-stage, N-stage, and extramural venous invasion. Based on the T-stage, tumors were divided in to locally advanced (T3cd-T4) and not locally advanced (T1-T3ab). Surgical and histopathological findings served as reference standard. Results: Using MRI, T-stage, N-stage, and extramural venous invasion were correctly predicted for each observer in 90% and 93%, 72% and 69%, and 82% and 78% of cases, respectively. With CT the corresponding results were 79% and 76%, 72% and 72%, 78% and 67%. For MRI inter-observer agreements (Kappa statistics) were 0.79, 0.10, and 0.76. For CT the corresponding results were 0.64, 0.66, and 0.22. Conclusion: Patients with locally advanced colon cancer, defined as tumor stage T3cd-T4, can be identified by both high resolution MRI and CT, even when CT is performed with a metastasis staging protocol. MRI may have an advantage, due to its high soft tissue discrimination, to identify certain prognostic factors such as T-stage and extramural venous invasion

Potentials of high resolution magnetic resonance imaging versus computed tomography for preoperative local staging of colon cancer

Energy Technology Data Exchange (ETDEWEB)

Rollven, Erik; Blomqvist, Lennart [Dept. of Diagnostic Radiology, Karolinska Univ. Hospital Solna, Stockholm (Sweden); Dept. of Molecular Medicine and Surgery, Karolinska Inst., Stockholm (Sweden)], e-mail: erik.rollven@ki.se; Holm, Torbjorn [Dept. of Molecular Medicine and Surgery, Karolinska Inst., Stockholm (Sweden); Dept. of Surgery, Karolinska Univ. Hospital Solna, Stockholm (Sweden); Glimelius, Bengt [Dept. of Radiology, Oncology and Radiation Science, Uppsala Univ., Uppsala (Sweden); Dept. of Oncology and Pathology, Karolinska Inst., Stockholm (Sweden); Loerinc, Esther [Dept. of Oncology and Pathology, Karolinska Inst., Stockholm (Sweden); Dept. of Pathology, Karolinska Univ. Hospital, Solna, Sweden (Sweden)

2013-09-15

Background: Preoperative identification of locally advanced colon cancer is of importance in order to properly plan treatment. Purpose: To study high resolution T2-weighted magnetic resonance imaging (MRI) versus computed tomography (CT) for preoperative staging of colon cancer with surgery and histopathology as reference standard. Material and Methods: Twenty-eight patients with a total of 29 tumors were included. Patients were examined on a 1.5 T MR unit using a phased array body coil. T2 turbo spin-echo high resolution sequences were obtained in a coronal, transverse, and perpendicular plane to the long axis of the colon at the site of the tumor. Contrast-enhanced CT was performed using a protocol for metastasis staging. The examinations were independently evaluated by two gastrointestinal radiologists using criteria adapted to imaging for prediction of T-stage, N-stage, and extramural venous invasion. Based on the T-stage, tumors were divided in to locally advanced (T3cd-T4) and not locally advanced (T1-T3ab). Surgical and histopathological findings served as reference standard. Results: Using MRI, T-stage, N-stage, and extramural venous invasion were correctly predicted for each observer in 90% and 93%, 72% and 69%, and 82% and 78% of cases, respectively. With CT the corresponding results were 79% and 76%, 72% and 72%, 78% and 67%. For MRI inter-observer agreements (Kappa statistics) were 0.79, 0.10, and 0.76. For CT the corresponding results were 0.64, 0.66, and 0.22. Conclusion: Patients with locally advanced colon cancer, defined as tumor stage T3cd-T4, can be identified by both high resolution MRI and CT, even when CT is performed with a metastasis staging protocol. MRI may have an advantage, due to its high soft tissue discrimination, to identify certain prognostic factors such as T-stage and extramural venous invasion.

The California Seafloor Mapping Program — Providing science and geospatial data for California's State Waters

Science.gov (United States)

Johnson, S. Y.; Cochrane, G. R.; Golden, N. E.; Dartnell, P.; Hartwell, S. R.; Cochran, S. A.; Watt, J. T.

2017-12-01

The California Seafloor Mapping Program (CSMP) is a collaborative effort to develop comprehensive bathymetric, geologic, and habitat maps and data for California's State Waters, which extend for 1,350 km from the shoreline to 5.6 km offshore. CSMP began in 2007 when the California Ocean Protection Council and NOAA allocated funding for high-resolution bathymetric mapping to support the California Marine Life Protection Act and update nautical charts. Collaboration and support from the USGS and other partners has led to development and dissemination of one of the world's largest seafloor-mapping datasets. CSMP data collection includes: (1) High-resolution bathymetric and backscatter mapping using swath sonar sensors; (2) "Ground-truth" imaging from a sled mounted with video and still cameras; (3) High-resolution seismic-reflection profiling at 1 km line spacing. Processed data are all publicly available. Additionally, 25 USGS map and datasets covering one third of California's coast have been published. Each publication contains 9 to 12 pdf map sheets (1:24,000 scale), an explanatory pamphlet, and a catalog of digital geospatial data layers (about 15 to 25 per map area) with web services. Map sheets display bathymetry, backscatter, perspective views, habitats, groundtruth imagery, seismic profiles, sediment distribution and thickness, and onshore-offshore geology. The CSMP goal is to serve a large constituency, ranging from senior GIS analysts in large agencies, to local governments with limited resources, to non-governmental organizations, the private sector, and concerned citizens. CSMP data and publications provide essential science and data for ocean and coastal management, stimulate and enable research, and raise public education and awareness of coastal and ocean issues. Specific applications include: Delineation and designation of marine protected areas Characterization and modeling of benthic habitats and ecosystems Updating nautical charts Earthquake hazard

Local network assessment

Science.gov (United States)

Glen, D. V.

1985-04-01

Local networks, related standards activities of the Institute of Electrical and Electronics Engineers the American National Standards Institute and other elements are presented. These elements include: (1) technology choices such as topology, transmission media, and access protocols; (2) descriptions of standards for the 802 local area networks (LAN's); high speed local networks (HSLN's) and military specification local networks; and (3) intra- and internetworking using bridges and gateways with protocols Interconnection (OSI) reference model. The convergence of LAN/PBX technology is also described.

Local likelihood estimation of complex tail dependence structures in high dimensions, applied to US precipitation extremes

KAUST Repository

Camilo, Daniela Castro

2017-10-02

In order to model the complex non-stationary dependence structure of precipitation extremes over the entire contiguous U.S., we propose a flexible local approach based on factor copula models. Our sub-asymptotic spatial modeling framework yields non-trivial tail dependence structures, with a weakening dependence strength as events become more extreme, a feature commonly observed with precipitation data but not accounted for in classical asymptotic extreme-value models. To estimate the local extremal behavior, we fit the proposed model in small regional neighborhoods to high threshold exceedances, under the assumption of local stationarity. This allows us to gain in flexibility, while making inference for such a large and complex dataset feasible. Adopting a local censored likelihood approach, inference is made on a fine spatial grid, and local estimation is performed taking advantage of distributed computing resources and of the embarrassingly parallel nature of this estimation procedure. The local model is efficiently fitted at all grid points, and uncertainty is measured using a block bootstrap procedure. An extensive simulation study shows that our approach is able to adequately capture complex, non-stationary dependencies, while our study of U.S. winter precipitation data reveals interesting differences in local tail structures over space, which has important implications on regional risk assessment of extreme precipitation events. A comparison between past and current data suggests that extremes in certain areas might be slightly wider in extent nowadays than during the first half of the twentieth century.

Local likelihood estimation of complex tail dependence structures in high dimensions, applied to US precipitation extremes

KAUST Repository

Camilo, Daniela Castro; Huser, Raphaë l

2017-01-01

In order to model the complex non-stationary dependence structure of precipitation extremes over the entire contiguous U.S., we propose a flexible local approach based on factor copula models. Our sub-asymptotic spatial modeling framework yields non-trivial tail dependence structures, with a weakening dependence strength as events become more extreme, a feature commonly observed with precipitation data but not accounted for in classical asymptotic extreme-value models. To estimate the local extremal behavior, we fit the proposed model in small regional neighborhoods to high threshold exceedances, under the assumption of local stationarity. This allows us to gain in flexibility, while making inference for such a large and complex dataset feasible. Adopting a local censored likelihood approach, inference is made on a fine spatial grid, and local estimation is performed taking advantage of distributed computing resources and of the embarrassingly parallel nature of this estimation procedure. The local model is efficiently fitted at all grid points, and uncertainty is measured using a block bootstrap procedure. An extensive simulation study shows that our approach is able to adequately capture complex, non-stationary dependencies, while our study of U.S. winter precipitation data reveals interesting differences in local tail structures over space, which has important implications on regional risk assessment of extreme precipitation events. A comparison between past and current data suggests that extremes in certain areas might be slightly wider in extent nowadays than during the first half of the twentieth century.

Local SAR in High Pass Birdcage and TEM Body Coils for Multiple Human Body Models in Clinical Landmark Positions at 3T

Science.gov (United States)

Yeo, Desmond TB; Wang, Zhangwei; Loew, Wolfgang; Vogel, Mika W; Hancu, Ileana

2011-01-01

Purpose To use EM simulations to study the effects of body type, landmark position, and RF body coil type on peak local SAR in 3T MRI. Materials and Methods Numerically computed peak local SAR for four human body models (HBMs) in three landmark positions (head, heart, pelvic) were compared for a high-pass birdcage and a transverse electromagnetic 3T body coil. Local SAR values were normalized to the IEC whole-body average SAR limit of 2.0 W/kg for normal scan mode. Results Local SAR distributions were highly variable. Consistent with previous reports, the peak local SAR values generally occurred in the neck-shoulder area, near rungs, or between tissues of greatly differing electrical properties. The HBM type significantly influenced the peak local SAR, with stockier HBMs, extending extremities towards rungs, displaying the highest SAR. There was also a trend for higher peak SAR in the head-centric and heart-centric positions. The impact of the coil-types studied was not statistically significant. Conclusion The large variability in peak local SAR indicates the need to include more than one HBM or landmark position when evaluating safety of body coils. It is recommended that a HBM with arms near the rungs be included, to create physically realizable high-SAR scenarios. PMID:21509880

An Unsupervised kNN Method to Systematically Detect Changes in Protein Localization in High-Throughput Microscopy Images.

Directory of Open Access Journals (Sweden)

Alex Xijie Lu

Full Text Available Despite the importance of characterizing genes that exhibit subcellular localization changes between conditions in proteome-wide imaging experiments, many recent studies still rely upon manual evaluation to assess the results of high-throughput imaging experiments. We describe and demonstrate an unsupervised k-nearest neighbours method for the detection of localization changes. Compared to previous classification-based supervised change detection methods, our method is much simpler and faster, and operates directly on the feature space to overcome limitations in needing to manually curate training sets that may not generalize well between screens. In addition, the output of our method is flexible in its utility, generating both a quantitatively ranked list of localization changes that permit user-defined cut-offs, and a vector for each gene describing feature-wise direction and magnitude of localization changes. We demonstrate that our method is effective at the detection of localization changes using the Δrpd3 perturbation in Saccharomyces cerevisiae, where we capture 71.4% of previously known changes within the top 10% of ranked genes, and find at least four new localization changes within the top 1% of ranked genes. The results of our analysis indicate that simple unsupervised methods may be able to identify localization changes in images without laborious manual image labelling steps.

An Unsupervised kNN Method to Systematically Detect Changes in Protein Localization in High-Throughput Microscopy Images.

Science.gov (United States)

Lu, Alex Xijie; Moses, Alan M

2016-01-01

Despite the importance of characterizing genes that exhibit subcellular localization changes between conditions in proteome-wide imaging experiments, many recent studies still rely upon manual evaluation to assess the results of high-throughput imaging experiments. We describe and demonstrate an unsupervised k-nearest neighbours method for the detection of localization changes. Compared to previous classification-based supervised change detection methods, our method is much simpler and faster, and operates directly on the feature space to overcome limitations in needing to manually curate training sets that may not generalize well between screens. In addition, the output of our method is flexible in its utility, generating both a quantitatively ranked list of localization changes that permit user-defined cut-offs, and a vector for each gene describing feature-wise direction and magnitude of localization changes. We demonstrate that our method is effective at the detection of localization changes using the Δrpd3 perturbation in Saccharomyces cerevisiae, where we capture 71.4% of previously known changes within the top 10% of ranked genes, and find at least four new localization changes within the top 1% of ranked genes. The results of our analysis indicate that simple unsupervised methods may be able to identify localization changes in images without laborious manual image labelling steps.

Inference for Local Distributions at High Sampling Frequencies: A Bootstrap Approach

DEFF Research Database (Denmark)

Hounyo, Ulrich; Varneskov, Rasmus T.

of "large" jumps. Our locally dependent wild bootstrap (LDWB) accommodate issues related to the stochastic scale and jumps as well as account for a special block-wise dependence structure induced by sampling errors. We show that the LDWB replicates first and second-order limit theory from the usual...... empirical process and the stochastic scale estimate, respectively, as well as an asymptotic bias. Moreover, we design the LDWB sufficiently general to establish asymptotic equivalence between it and and a nonparametric local block bootstrap, also introduced here, up to second-order distribution theory....... Finally, we introduce LDWB-aided Kolmogorov-Smirnov tests for local Gaussianity as well as local von-Mises statistics, with and without bootstrap inference, and establish their asymptotic validity using the second-order distribution theory. The finite sample performance of CLT and LDWB-aided local...

Fatigue Life Prediction of High Modulus Asphalt Concrete Based on the Local Stress-Strain Method

Directory of Open Access Journals (Sweden)

Mulian Zheng

2017-03-01

Full Text Available Previously published studies have proposed fatigue life prediction models for dense graded asphalt pavement based on flexural fatigue test. This study focused on the fatigue life prediction of High Modulus Asphalt Concrete (HMAC pavement using the local strain-stress method and direct tension fatigue test. First, the direct tension fatigue test at various strain levels was conducted on HMAC prism samples cut from plate specimens. Afterwards, their true stress-strain loop curves were obtained and modified to develop the strain-fatigue life equation. Then the nominal strain of HMAC course determined using finite element method was converted into local strain using the Neuber method. Finally, based on the established fatigue equation and converted local strain, a method to predict the pavement fatigue crack initiation life was proposed and the fatigue life of a typical HMAC overlay pavement which runs a risk of bottom-up cracking was predicted and validated. Results show that the proposed method was able to produce satisfactory crack initiation life.

Local antiferromagnetic exchange and collaborative Fermi surface as key ingredients of high temperature superconductors

Science.gov (United States)

Hu, Jiangping; Ding, Hong

2012-01-01

Cuprates, ferropnictides and ferrochalcogenides are three classes of unconventional high temperature superconductors, who share similar phase diagrams in which superconductivity develops after a magnetic order is suppressed, suggesting a strong interplay between superconductivity and magnetism, although the exact picture of this interplay remains elusive. Here we show that there is a direct bridge connecting antiferromagnetic exchange interactions determined in the parent compounds of these materials to the superconducting gap functions observed in the corresponding superconducting materials: in all high temperature superconductors, the Fermi surface topology matches the form factor of the pairing symmetry favored by local magnetic exchange interactions. We suggest that this match offers a principle guide to search for new high temperature superconductors. PMID:22536479

Oxidative stress does not influence local sweat rate during high-intensity exercise.

Science.gov (United States)

Meade, Robert D; Fujii, Naoto; Poirier, Martin P; Boulay, Pierre; Sigal, Ronald J; Kenny, Glen P

2018-02-01

What is the central question of this study? We evaluated whether oxidative stress attenuates the contribution of nitric oxide to sweating during high-intensity exercise. What is the main finding and its importance? In contrast to our previous report of an oxidative stress-mediated reduction in nitric oxide-dependent cutaneous vasodilatation in this cohort during intense exercise, we demonstrated no influence of local ascorbate administration on the sweating response during moderate- (∼51% peak oxygen uptake) or high-intensity exercise (∼72% peak oxygen uptake). These new findings provide important mechanistic insight into how exercise-induced oxidative stress impacts sudomotor activity. Nitric oxide (NO)-dependent sweating is diminished during high- but not moderate-intensity exercise. We evaluated whether this impairment stems from increased oxidative stress during high-intensity exercise. On two separate days, 11 young (24 ± 4 years) men cycled in the heat (35°C) at a moderate [500 W; 52 ± 6% peak oxygen uptake (V̇O2 peak )] or high (700 W; 71 ± 5% V̇O2 peak ) rate of metabolic heat production. Each session included two 30 min exercise bouts separated by a 20 min recovery period. Local sweat rate was monitored at four forearm skin sites continuously perfused via intradermal microdialysis with the following: (i) lactated Ringer solution (Control); (ii) 10 mm ascorbate (Ascorbate; non-selective antioxidant); (iii) 10 mm N G -nitro-l-arginine methyl ester (l-NAME; NO synthase inhibitor); or (iv) 10 mm ascorbate plus 10 mm l-NAME (Ascorbate + l-NAME). During moderate exercise, sweat rate was attenuated at the l-NAME and Ascorbate + l-NAME sites (both ∼1.0 mg min -1  cm -2 ; all P < 0.05) but not at the Ascorbate site (∼1.1 mg min -1  cm -2 ; both P ≥ 0.28) in comparison to the Control site (∼1.1 mg min -1  cm -2 ). However, no differences were observed between treatment sites (∼1.4 mg min -1  cm -2 ; P = 0

A high figure of merit localized surface plasmon sensor based on a gold nanograting on the top of a gold planar film

International Nuclear Information System (INIS)

Zhang Zu-Yin; Wang Li-Na; Hu Hai-Feng; Li Kang-Wen; Ma Xun-Peng; Song Guo-Feng

2013-01-01

We investigate the sensitivity and figure of merit (FOM) of a localized surface plasmon (LSP) sensor with gold nanograting on the top of planar metallic film. The sensitivity of the localized surface plasmon sensor is 317 nm/RIU, and the FOM is predicted to be above 8, which is very high for a localized surface plasmon sensor. By employing the rigorous coupled-wave analysis (RCWA) method, we analyze the distribution of the magnetic field and find that the sensing property of our proposed system is attributed to the interactions between the localized surface plasmon around the gold nanostrips and the surface plasmon polarition on the surface of the gold planar metallic film. These findings are important for developing high FOM localized surface plasmon sensors. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

Attending to global versus local stimulus features modulates neural processing of low versus high spatial frequencies: An analysis with event-related brain potentials.

Directory of Open Access Journals (Sweden)

Anastasia V Flevaris

2014-04-01

Full Text Available Spatial frequency (SF selection has long been recognized to play a role in global and local processing, though the nature of the relationship between SF processing and global/local perception is debated. Previous studies have shown that attention to relatively lower SFs facilitates global perception, and that attention to relatively higher SFs facilitates local perception. Here we recorded event-related brain potentials (ERPs to investigate whether processing of low versus high SFs is modulated automatically during global and local perception, and to examine the time course of any such effects. Participants compared bilaterally presented hierarchical letter stimuli and attended to either the global or local levels. Irrelevant SF grating probes flashed at the center of the display 200 ms after the onset of the hierarchical letter stimuli could either be low or high in SF. It was found that ERPs elicited by the SF grating probes differed as a function of attended level (global vs. local. ERPs elicited by low SF grating probes were more positive in the interval 196-236 ms during global than local attention, and this difference was greater over the right occipital scalp. In contrast, ERPs elicited by the high SF gratings were more positive in the interval 250-290 ms during local than global attention, and this difference was bilaterally distributed over the occipital scalp. These results indicate that directing attention to global versus local levels of a hierarchical display facilitates automatic perceptual processing of low versus high SFs, respectively, and this facilitation is not limited to the locations occupied by the hierarchical display. The relatively long latency of these attention-related ERP modulations suggests that initial (early SF processing is not affected by attention to hierarchical level, lending support to theories positing a higher level mechanism to underlie the relationship between SF processing and global versus local

Genomic signatures of local directional selection in a high gene flow marine organism; the Atlantic cod (Gadus morhua

Directory of Open Access Journals (Sweden)

Mittelholzer Christian

2009-12-01

Full Text Available Abstract Background Marine fishes have been shown to display low levels of genetic structuring and associated high levels of gene flow, suggesting shallow evolutionary trajectories and, possibly, limited or lacking adaptive divergence among local populations. We investigated variation in 98 gene-associated single nucleotide polymorphisms (SNPs for evidence of selection in local populations of Atlantic cod (Gadus morhua L. across the species distribution. Results Our global genome scan analysis identified eight outlier gene loci with very high statistical support, likely to be subject to directional selection in local demes, or closely linked to loci under selection. Likewise, on a regional south/north transect of central and eastern Atlantic populations, seven loci displayed strongly elevated levels of genetic differentiation. Selection patterns among populations appeared to be relatively widespread and complex, i.e. outlier loci were generally not only associated with one of a few divergent local populations. Even on a limited geographical scale between the proximate North Sea and Baltic Sea populations four loci displayed evidence of adaptive evolution. Temporal genome scan analysis applied to DNA from archived otoliths from a Faeroese population demonstrated stability of the intra-population variation over 24 years. An exploratory landscape genetic analysis was used to elucidate potential effects of the most likely environmental factors responsible for the signatures of local adaptation. We found that genetic variation at several of the outlier loci was better correlated with temperature and/or salinity conditions at spawning grounds at spawning time than with geographic distance per se. Conclusion These findings illustrate that adaptive population divergence may indeed be prevalent despite seemingly high levels of gene flow, as found in most marine fishes. Thus, results have important implications for our understanding of the interplay of

Radiotherapy and androgen ablation for clinically localized high-risk prostate cancer

Energy Technology Data Exchange (ETDEWEB)

Pollack, Alan; Zagars, Gunar K; Kopplin, Susan

1995-04-30

Purpose: The response of patients with clinical stages T1-4 prostate cancer to radiotherapy is variable. A particularly poor prognostic group has been found to be comprised of those with pretreatment prostate specific antigen (PSA) levels above 30 ng/ml with any tumor grade, or PSA levels > 10 and {<=} 30 with tumors grade 3 or 4. These patients have over an 80% actuarial risk of biochemical failure 3 years after definitive external beam radiotherapy. Thus, patients with these high-risk features require more aggressive therapy. During the last 3-4 years, the policy to treat such patients with radiotherapy and androgen ablation (XRT/HORM) was instituted. A retrospective comparison was made between high-risk patients treated with radiotherapy alone (XRT) vs. XRT/HORM. Methods and Materials: Between 1987 and 1991, there were 81 high-risk patients treated with XRT. There were 38 high-risk patients treated with XRT/HORM between 1990 and 1992. The median follow-up was 37 months for the XRT group and 22 months for the XRT/HORM group. No patient had clinical, radiographic, or pathologic evidence of lymph node involvement. The median dose to the prostate was 66 Gy for the XRT group and 68 Gy for the XRT/HORM group. Results: The distributions of several potential prognostic factors were analyzed. Significant differences between the groups were observed for tumor grade, pretreatment prostatic acid phosphatase, and age. The XRT/HORM group was composed of patients with worse features, including a greater proportion of patients with grade 4 tumors, more with abnormal acid phosphatase levels, and more under 60 years of age. The actuarial incidence of a rising PSA at 3 years for the XRT group was 81% vs. 15% for the XRT/HORM group (p < 0.0001). In addition, local relapse at 3 years was 34% for the XRT group and 15% for the XRT/HORM group (p < 0.02). There was no difference between the groups in terms of survival. Cox proportional hazards analyses were performed using several

The Origin and Evolution of Interstellar Dust in the Local and High-redshift Universe

Science.gov (United States)

Dwek, Eliahu

2012-01-01

In this talk I will begin by reviewing our current state of knowledge regarding the origin and evolution of dust in the local solar neighborhood. using chemical evolution models, I will discuss their many different input parameters and their uncertainties. An important consequence of these models is the delayed injection of dust from AGB stars, compared to supernova-condensed dust, into the interstellar medium. I will show that these stellar evolutionary effects on dust composition are manifested in the infrared spectra of local galaxies. The delayed production of dust in AGB stars has also important consequences for the origin of the large amount of dust detected in high-redshift galaxies, when the universe was less that approx. 1 Gyr old. Supernovae may have been the only viable dust sources in those galaxies. Recent observations of sN1987a show a significant mass of dust in the ejecta of this SN. Is that production rate high enough to account for the observed dust mass in these galaxies? If not, what are the alternative viable sources of dust, and how do they depend on the nature of the galaxy (starburst or AGN) and its star formation history .

Processing and performance of topobathymetric lidar data for geomorphometric and morphological classification in a high-energy tidal environment

DEFF Research Database (Denmark)

Andersen, Mikkel Skovgaard; Gergely, Áron; Al-Hamdani, Zyad K.

2017-01-01

of detecting features with a size of less than 1 m2. The derived high-resolution DEM was applied for detection and classification of geomorphometric and morphological features within the natural environment of the study area. Initially, the bathymetric position index (BPI) and the slope of the DEM were used...... area into six specific types of morphological features (i.e. subtidal channel, intertidal flat, intertidal creek, linear bar, swash bar and beach dune). The developed classification method is adapted and applied to a specific case, but it can also be implemented in other cases and environments....

High-speed railway real-time localization auxiliary method based on deep neural network

Science.gov (United States)

Chen, Dongjie; Zhang, Wensheng; Yang, Yang

2017-11-01

High-speed railway intelligent monitoring and management system is composed of schedule integration, geographic information, location services, and data mining technology for integration of time and space data. Assistant localization is a significant submodule of the intelligent monitoring system. In practical application, the general access is to capture the image sequences of the components by using a high-definition camera, digital image processing technique and target detection, tracking and even behavior analysis method. In this paper, we present an end-to-end character recognition method based on a deep CNN network called YOLO-toc for high-speed railway pillar plate number. Different from other deep CNNs, YOLO-toc is an end-to-end multi-target detection framework, furthermore, it exhibits a state-of-art performance on real-time detection with a nearly 50fps achieved on GPU (GTX960). Finally, we realize a real-time but high-accuracy pillar plate number recognition system and integrate natural scene OCR into a dedicated classification YOLO-toc model.

A geomorphologist's dream come true: synoptic high resolution river bathymetry with the latest generation of airborne dual wavelength lidar

Science.gov (United States)

Lague, Dimitri; Launeau, Patrick; Michon, Cyril; Gouraud, Emmanuel; Juge, Cyril; Gentile, William; Hubert-Moy, Laurence; Crave, Alain

2016-04-01

Airborne, terrestrial lidar and Structure From Motion have dramatically changed our approach of geomorphology, from low density/precision data, to a wealth of data with a precision adequate to actually measure topographic change across multiple scales, and its relation to vegetation. Yet, an important limitation in the context of fluvial geomorphology has been the inability of these techniques to penetrate water due to the use of NIR laser wavelengths or to the complexity of accounting for water refraction in SFM. Coastal bathymetric systems using a green lidar can penetrate clear water up to 50 m but have a resolution too coarse and deployment costs that are prohibitive for fluvial research and management. After early prototypes of narrow aperture green lidar (e.g., EEARL NASA), major lidar manufacturer are now releasing dual wavelength laser system that offer water penetration consistent with shallow fluvial bathymetry at very high resolution (> 10 pts/m²) and deployment costs that makes the technology, finally accessible. This offers unique opportunities to obtain synoptic high resolution, high precision data for academic research as well as for fluvial environment management (flood risk mapping, navigability,…). In this presentation, we report on the deployment of the latest generation Teledyne-Optech Titan dual-wavelength lidar (1064 nm + 532 nm) owned by the University of Nantes and Rennes. The instrument has been deployed over several fluvial and lacustrine environments in France. We present results and recommendation on how to optimize the bathymetric cover as a function of aerial and aquatic vegetation cover and the hydrology regime of the river. In the surveyed rivers, the penetration depth varies from 0.5 to 4 m with discrete echoes (i.e., onboard detection), heavily impacted by water clarity and bottom reflectance. Simple post-processing of the full waveform record allows to recover an additional 20 % depth. As for other lidar techniques, the main

Very High-Risk Localized Prostate Cancer: Outcomes Following Definitive Radiation

International Nuclear Information System (INIS)

Narang, Amol K.; Gergis, Carol; Robertson, Scott P.; He, Pei; Ram, Ashwin N.; McNutt, Todd R.; Griffith, Emily; DeWeese, Theodore A.; Honig, Stephanie; Singh, Harleen; Song, Danny Y.; Tran, Phuoc T.; DeWeese, Theodore L.

2016-01-01

Purpose: Existing definitions of high-risk prostate cancer consist of men who experience significant heterogeneity in outcomes. As such, criteria that identify a subpopulation of National Comprehensive Cancer Network (NCCN) high-risk prostate cancer patients who are at very high risk (VHR) for poor survival outcomes following prostatectomy were recently developed at our institution and include the presence of any of the following disease characteristics: multiple NCCN high-risk factors, primary Gleason pattern 5 disease and/or ≥5 biopsy cores with Gleason sums of 8 to 10. Whether these criteria also apply to men undergoing definitive radiation is unclear, as is the optimal treatment regimen in these patients. Methods and Materials: All men consecutively treated with definitive radiation by a single provider from 1993 to 2006 and who fulfilled criteria for NCCN high-risk disease were identified (n=288), including 99 patients (34%) with VHR disease. Multivariate-adjusted competing risk regression models were constructed to assess associations between the VHR definition and biochemical failure (BF), distant metastasis (DM), and prostate cancer–specific mortality (PCSM). Multivariate-adjusted Cox regression analysis assessed the association of the VHR definition with overall mortality (OM). Cumulative incidences of failure endpoints were compared between VHR men and other NCCN high-risk men. Results: Men with VHR disease compared to other NCCN high-risk men experienced a higher 10-year incidence of BF (54.0% vs 35.4%, respectively, P<.001), DM (34.9% vs 13.4%, respectively, P<.001), PCSM (18.5% vs 5.9%, respectively, P<.001), and OM (36.4% vs 27.0%, respectively, P=.04). VHR men with a detectable prostate-specific antigen (PSA) concentration at the end of radiation (EOR) remained at high risk of 10-year PCSM compared to VHR men with an undetectable EOR PSA (31.0% vs 13.7%, respectively, P=.05). Conclusions: NCCN high-risk prostate cancer patients who meet VHR

Complete surgical resection improves outcome in INRG high-risk patients with localized neuroblastoma older than 18 months.

Science.gov (United States)

Fischer, Janina; Pohl, Alexandra; Volland, Ruth; Hero, Barbara; Dübbers, Martin; Cernaianu, Grigore; Berthold, Frank; von Schweinitz, Dietrich; Simon, Thorsten

2017-08-04

Although several studies have been conducted on the role of surgery in localized neuroblastoma, the impact of surgical timing and extent of primary tumor resection on outcome in high-risk patients remains controversial. Patients from the German neuroblastoma trial NB97 with localized neuroblastoma INSS stage 1-3 age > 18 months were included for retrospective analysis. Imaging reports were reviewed by two independent physicians for Image Defined Risk Factors (IDRF). Operation notes and corresponding imaging reports were analyzed for surgical radicality. The extent of tumor resection was classified as complete resection (95-100%), gross total resection (90-95%), incomplete resection (50-90%), and biopsy (Neuroblastoma Risk Group (INRG) staging system. Survival curves were estimated according to the method of Kaplan and Meier and compared by the log-rank test. A total of 179 patients were included in this study. 77 patients underwent more than one primary tumor operation. After best surgery, 68.7% of patients achieved complete resection of the primary tumor, 16.8% gross total resection, 14.0% incomplete surgery, and 0.5% biopsy only. The cumulative complication rate was 20.3% and the surgery associated mortality rate was 1.1%. Image defined risk factors (IDRF) predicted the extent of resection. Patients with complete resection had a better local-progression-free survival (LPFS), event-free survival (EFS) and OS (overall survival) than the other groups. Subgroup analyses showed better EFS, LPFS and OS for patients with complete resection in INRG high-risk patients. Multivariable analyses revealed resection (complete vs. other), and MYCN (non-amplified vs. amplified) as independent prognostic factors for EFS, LPFS and OS. In patients with localized neuroblastoma age 18 months or older, especially in INRG high-risk patients harboring MYCN amplification, extended surgery of the primary tumor site improved local control rate and survival with an acceptable risk of

Specific Localization of High-Voltage Discharge in Vicinity of Two Gases

Science.gov (United States)

Leonov, Sergey; Shurupov, Michail; Shneider, Michail; Napartovich, Anatoly; Kochetov, Igor

2011-10-01

A subject of paper is the appearance and dynamics of sub-microsecond long filamentary high-voltage discharge generated in atmosphere, and in non-homogeneous gaseous media. Typical discharge parameters are: maximal current 1-3kA, breakdown voltage >100 kV, duration 30-100 ns, gap distance 50-100mm. The effect of discharge specific localization within mixing layer of two gases is particularly discussed. The second discussed idea is the filamentary discharge movement within a region with concentration gradient of different components. For the short-pulse discharge the physical mechanism appears as the following. The first stage of the spark breakdown is the multiple streamers propagation from the high-voltage electrode toward the grounded one. In case of high-power electrical source those streamers occupy a huge volume of the gas, covering all possible paths for the further development. The next phase consists of the real selection of the discharge path among the multiple channels with non-zero conductivity. Experiments and calculations are presented for Air-CO2 and Air-C2H4 pairs. The effects found are supposed to be applied for lightning prediction/protection, and for high-speed mixing acceleration. The work was funded through EOARD-ISTC project #3793p. Some part of this work was supported by RFBR grant #10-08-00952.

Improving maternal and neonatal departments in high and low resource settings: the opinion of local health providers.

Science.gov (United States)

Trevisanuto, Daniele; Bavuusuren, Bayasgalantai; Wickramasinghe, Chandani S; Dharmaratne, Saminda M; Doglioni, Nicoletta; Giordan, Alessia; Zanardo, Vincenzo; Carlo, Waldemar A

2011-10-01

We compared local health caregivers' opinions regarding the priority areas for improving the maternal and neonatal departments in low and high resource countries. Personnel involved in maternal and neonatal care operating in level III, teaching hospitals in four countries (Sri Lanka, Mongolia, USA, and Italy) were asked to fill out an anonymous, written questionnaire. The questionnaire was completed by 1112 out of 1265 (87.9%) participants. "Personnel's education" was classified as the first most important intervention by health providers working in high (49.0%) as well as in low (29.9%) resource countries, respectively. Improvement in salary, equipment, internet access, and organizational protocols were considered as the most important interventions by a significantly larger percentage of personnel from low resource countries in comparison with those from high resource countries. Health providers from high resource countries considered organizational aspects (to define specific roles and responsibilities) as a priority more frequently than their colleagues from low resource countries. Although education of personnel was valued as the highest priority for improving maternal and neonatal departments there are substantial differences in priorities associated with the working setting. Local caregivers' opinion may contribute to better design interventions in settings with high or limited resources.

MgB_{2} nonlinear properties investigated under localized high rf magnetic field excitation

Directory of Open Access Journals (Sweden)

Tamin Tai

2012-12-01

Full Text Available The high transition temperature and low surface resistance of MgB_{2} attracts interest in its potential application in superconducting radio frequency accelerating cavities. However, compared to traditional Nb cavities, the viability of MgB_{2} at high rf fields is still open to question. Our approach is to study the nonlinear electrodynamics of the material under localized rf magnetic fields. Because of the presence of the small superconducting gap in the π band, the nonlinear response of MgB_{2} at low temperature is potentially complicated compared to a single-gap s-wave superconductor such as Nb. Understanding the mechanisms of nonlinearity coming from the two-band structure of MgB_{2}, as well as extrinsic sources of nonlinearity, is an urgent requirement. A localized and strong rf magnetic field, created by a magnetic write head, is integrated into our nonlinear-Meissner-effect scanning microwave microscope [T. Tai et al., IEEE Trans. Appl. Supercond. 21, 2615 (2011ITASE91051-822310.1109/TASC.2010.2096531]. MgB_{2} films with thickness 50 nm, fabricated by a hybrid physical-chemical vapor deposition technique on dielectric substrates, are measured at a fixed location and show a strongly temperature-dependent third harmonic response. We propose that several possible mechanisms are responsible for this nonlinear response.

Multiscale finite element methods for high-contrast problems using local spectral basis functions

KAUST Repository

Efendiev, Yalchin

2011-02-01

In this paper we study multiscale finite element methods (MsFEMs) using spectral multiscale basis functions that are designed for high-contrast problems. Multiscale basis functions are constructed using eigenvectors of a carefully selected local spectral problem. This local spectral problem strongly depends on the choice of initial partition of unity functions. The resulting space enriches the initial multiscale space using eigenvectors of local spectral problem. The eigenvectors corresponding to small, asymptotically vanishing, eigenvalues detect important features of the solutions that are not captured by initial multiscale basis functions. Multiscale basis functions are constructed such that they span these eigenfunctions that correspond to small, asymptotically vanishing, eigenvalues. We present a convergence study that shows that the convergence rate (in energy norm) is proportional to (H/Λ*)1/2, where Λ* is proportional to the minimum of the eigenvalues that the corresponding eigenvectors are not included in the coarse space. Thus, we would like to reach to a larger eigenvalue with a smaller coarse space. This is accomplished with a careful choice of initial multiscale basis functions and the setup of the eigenvalue problems. Numerical results are presented to back-up our theoretical results and to show higher accuracy of MsFEMs with spectral multiscale basis functions. We also present a hierarchical construction of the eigenvectors that provides CPU savings. © 2010.

The valorization of local aggregates in the manufacturing of high-performance concrete (case study of Southwest of Algeria)

International Nuclear Information System (INIS)

Rikioui, T.; Abdelaziz, Y.; Mekkaoui, A.

2012-01-01

On the basis of an experimental program to achieve an optimization of formulations of high performance concretes (HPC) based on local aggregates, a study was conducted to identify the physicochemical and mechanical properties of the aggregates locally available at the city of Bechar (southwest Algeria). A comparative estimate study between the conventional concrete and its HPC equivalent was also initiated. Finally, potential applications are commented using two practical case. (author)

Physical-biological coupling induced aggregation mechanism for the formation of high biomass red tides in low nutrient waters.

Science.gov (United States)

Lai, Zhigang; Yin, Kedong

2014-01-01

Port Shelter is a semi-enclosed bay in northeast Hong Kong where high biomass red tides are observed to occur frequently in narrow bands along the local bathymetric isobars. Previous study showed that nutrients in the Bay are not high enough to support high biomass red tides. The hypothesis is that physical aggregation and vertical migration of dinoflagellates appear to be the driving mechanism to promote the formation of red tides in this area. To test this hypothesis, we used a high-resolution estuarine circulation model to simulate the near-shore water dynamics based on in situ measured temperature/salinity profiles, winds and tidal constitutes taken from a well-validated regional tidal model. The model results demonstrated that water convergence occurs in a narrow band along the west shore of Port Shelter under a combined effect of stratified tidal current and easterly or northeasterly wind. Using particles as dinoflagellate cells and giving diel vertical migration, the model results showed that the particles aggregate along the convergent zone. By tracking particles in the model predicted current field, we estimated that the physical-biological coupled processes induced aggregation of the particles could cause 20-45 times enhanced cell density in the convergent zone. This indicated that a high cell density red tide under these processes could be initialized without very high nutrients concentrations. This may explain why Port Shelter, a nutrient-poor Bay, is the hot spot for high biomass red tides in Hong Kong in the past 25 years. Our study explains why red tide occurrences are episodic events and shows the importance of taking the physical-biological aggregation mechanism into consideration in the projection of red tides for coastal management. Copyright © 2013 Elsevier B.V. All rights reserved.

Rainforest pharmacopeia in Madagascar provides high value for current local and prospective global uses.

Directory of Open Access Journals (Sweden)

Christopher D Golden

Full Text Available Botanical diversity provides value to humans through carbon sequestration, air and water purification, and the provisioning of wild foods and ethnomedicines. Here we calculate the value of botanical ethnomedicines in a rainforest region of Madagascar, the Makira Protected Area, using a substitution method that combines replacement costs and choice modeling. The Makira watershed may comprise approximately 0.8% of global botanical diversity and possesses enormous value both in its ability to provision botanical ethnomedicines to local people and as a source of potentially novel pharmaceutical drugs for society as a whole. Approximately 241 locally-recognized species are used as ethnomedicines, including 113 agricultural or weed species. We equated each ethnomedicinal treatment to the monetary value of a comparable pharmaceutical treatment adjusted by personal preferences in perceived efficacy (rather than from known or assumed medicinal equivalency. The benefit value of these botanical ethnomedicines per individual is $5.40-7.90 per year when using the value of highly subsidized Malagasy pharmaceuticals and $100.60-287.40 when using the value of American pharmaceuticals. Using local pharmaceuticals as substitutes, the value per household is $30.24-44.30 per year, equivalent to 43-63% of median annual household income, demonstrating their local importance. Using the value of American pharmaceuticals, the amount is equivalent to 22-63% of the median annual health care expenditures for American adults under 45 in 2006. The potential for developing novel biomedicines from the Makira watershed's unique flora ranges in untapped benefit value from $0.3-5.7 billion for American pharmaceutical companies, non-inclusive of the importance of providing novel medicines and improved healthcare to society. This study provides evidence of the tremendous current local and prospective global value of botanical ethnomedicines and furthers arguments for the

Local Information Processing in Adults with High Functioning Autism and Asperger Syndrome: The Usefulness of Neuropsychological Tests and Self-Reports

Science.gov (United States)

Spek, Annelies A.; Scholte, Evert M.; Van Berckelaer-Onnes, Ina A.

2011-01-01

Local information processing in 42 adults with high functioning autism, 41 adults with Asperger syndrome and 41 neurotypical adults was examined. Contrary to our expectations, the disorder groups did not outperform the neurotypical group in the neuropsychological measures of local information processing. In line with our hypotheses, the…

Scanning, Multibeam, Single Photon Lidars for Rapid, Large Scale, High Resolution, Topographic and Bathymetric Mapping

Directory of Open Access Journals (Sweden)

John J. Degnan

2016-11-01

Full Text Available Several scanning, single photon sensitive, 3D imaging lidars are herein described that operate at aircraft above ground levels (AGLs between 1 and 11 km, and speeds in excess of 200 knots. With 100 beamlets and laser fire rates up to 60 kHz, we, at the Sigma Space Corporation (Lanham, MD, USA, have interrogated up to 6 million ground pixels per second, all of which can record multiple returns from volumetric scatterers such as tree canopies. High range resolution has been achieved through the use of subnanosecond laser pulsewidths, detectors and timing receivers. The systems are presently being deployed on a variety of aircraft to demonstrate their utility in multiple applications including large scale surveying, bathymetry, forestry, etc. Efficient noise filters, suitable for near realtime imaging, have been shown to effectively eliminate the solar background during daytime operations. Geolocation elevation errors measured to date are at the subdecimeter level. Key differences between our Single Photon Lidars, and competing Geiger Mode lidars are also discussed.

Favorable Local Control From Consolidative Radiation Therapy in High-Risk Neuroblastoma Despite Gross Residual Disease, Positive Margins, or Nodal Involvement

Energy Technology Data Exchange (ETDEWEB)

Ferris, Matthew J., E-mail: mjferri@emory.edu [Department of Radiation Oncology, Emory University, Atlanta, Georgia (United States); Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Danish, Hasan [Department of Radiation Oncology, Emory University, Atlanta, Georgia (United States); Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Switchenko, Jeffrey M. [Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia (United States); Deng, Claudia [Department of Radiation Oncology, Emory University, Atlanta, Georgia (United States); Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); George, Bradley A.; Goldsmith, Kelly C.; Wasilewski, Karen J.; Cash, W. Thomas [Aflac Cancer and Blood Disorders Center, Children' s Healthcare of Atlanta, Atlanta, Georgia (United States); Khan, Mohammad K.; Eaton, Bree R.; Esiashvili, Natia [Department of Radiation Oncology, Emory University, Atlanta, Georgia (United States); Winship Cancer Institute, Emory University, Atlanta, Georgia (United States)

2017-03-15

Purpose: To report the influence of radiation therapy (RT) dose and surgical pathology variables on disease control and overall survival (OS) in patients treated for high-risk neuroblastoma at a single institution. Methods and Materials: We conducted a retrospective study of 67 high-risk neuroblastoma patients who received RT as part of definitive management from January 2003 until May 2014. Results: At a median follow-up of 4.5 years, 26 patients (38.8%) failed distantly; 4 of these patients also failed locally. One patient progressed locally without distant failure. Local control was 92.5%, and total disease control was 59.5%. No benefit was demonstrated for RT doses over 21.6 Gy with respect to local relapse–free survival (P=.55), disease-free survival (P=.22), or OS (P=.72). With respect to local relapse–free survival, disease-free survival, and OS, no disadvantage was seen for positive lymph nodes on surgical pathology, positive surgical margins, or gross residual disease. Of the patients with gross residual disease, 75% (6 of 8) went on to have no evidence of disease at time of last follow-up, and the 2 patients who failed did so distantly. Conclusions: Patients with high-risk neuroblastoma in this series maintained excellent local control, with no benefit demonstrated for radiation doses over 21.6 Gy, and no disadvantage demonstrated for gross residual disease after surgery, positive surgical margins, or pathologic lymph node positivity. Though the limitations of a retrospective review for an uncommon disease must be kept in mind, with small numbers in some of the subgroups, it seems that dose escalation should be considered only in exceptional circumstances.

The Local-Cosmopolitan Scientist

Directory of Open Access Journals (Sweden)

Barney G. Glaser, Ph.D., Hon. Ph.D.

2011-12-01

Full Text Available In contrast to previous discussions in the literature treating cosmopolitan and local as two distinct groups of scientists, this paperi demonstrates the notion of cosmopolitan and local as a dual orientation of highly motivated scientists. This dual orientation is derived from institutional motivation, which is a determinant of both high quality basic research and accomplishment of non-research organizational activities. The dual orientation arises in a context of similarity of the institutional goal of science with the goal of the organization; the distinction between groups of locals and cosmopolitans derives from a conflict between two goals.

A new seamless, high-resolution digital elevation model of the San Francisco Bay-Delta Estuary, California

Science.gov (United States)

Fregoso, Theresa A.; Wang, Rueen-Fang; Ateljevich, Eli; Jaffe, Bruce E.

2017-06-14

Climate change, sea-level rise, and human development have contributed to the changing geomorphology of the San Francisco Bay - Delta (Bay-Delta) Estuary system. The need to predict scenarios of change led to the development of a new seamless, high-resolution digital elevation model (DEM) of the Bay – Delta that can be used by modelers attempting to understand potential future changes to the estuary system. This report details the three phases of the creation of this DEM. The first phase took a bathymetric-only DEM created in 2005 by the U.S. Geological Survey (USGS), refined it with additional data, and identified areas that would benefit from new surveys. The second phase began a USGS collaboration with the California Department of Water Resources (DWR) that updated a 2012 DWR seamless bathymetric/topographic DEM of the Bay-Delta with input from the USGS and modifications to fit the specific needs of USGS modelers. The third phase took the work from phase 2 and expanded the coverage area in the north to include the Yolo Bypass up to the Fremont Weir, the Sacramento River up to Knights Landing, and the American River up to the Nimbus Dam, and added back in the elevations for interior islands. The constant evolution of the Bay-Delta will require continuous updates to the DEM of the Delta, and there still are areas with older data that would benefit from modern surveys. As a result, DWR plans to continue updating the DEM.

Preparing for Local Labor: Curricular Stratification across Local Economies in the United States

Science.gov (United States)

Sutton, April

2017-01-01

I investigate how the educational demands of local labor markets shape high school course offerings and student course taking. Using the Education Longitudinal Study of 2002 linked to the U.S. Census 2000, I focus on local economic variation in the share of jobs that do not demand a bachelor’s degree. I find that schools in local labor markets with higher concentrations of subbaccalaureate jobs devote a larger share of their course offerings to career and technical education (CTE) courses and a smaller share to advanced college-preparatory courses compared to schools in labor markets with lower concentrations of subbaccalaureate jobs, even net of school resources. Students in labor markets with higher concentrations of subbaccalaureate jobs take greater numbers of CTE courses, and higher-achieving students in these labor markets are less likely to take advanced math and Advanced Placement/International Baccalaureate courses. These course-taking disparities are largely due to school course offerings. This study shows how local economic inequalities shape high school curricular stratification, and suggests that school curricula linked to the educational demands of local jobs delimits the college preparation opportunities of high-achieving students. PMID:29531407

Localization of plastic yield and fracture mechanism in high-strength niobium alloy with ultra-fine particles of non-metallic phase

International Nuclear Information System (INIS)

Tyumentsev, A.N.; Gonchikov, V.Ch.; Korotaev, A.D.; Pinzhin, Yu.P.; Tyumentseva, S.F.

1989-01-01

The regularities of localization of plastic flow in high-strength dispersion-strengthened niobium alloy are studied. On the basis of investigations of the microstructure of strain localization zones the mechanism of stability losses of plastic flow including, the processes of diffusion of nonequilibrium vacancies in fields of nonuniform stresses, is proposed. The role of diffuse strain mechanisms during reorientation of the crystalline lattice is discussed. The regularities of fracture of high-strength alloy under conditions of rotational-shift instability of plastic flow are investigated

Localized deformation via multiple twinning in a Mg–Gd–Y–Zr alloy processed by high-pressure torsion

International Nuclear Information System (INIS)

Tang, Lingling; Zhao, Yonghao; Liang, Ningning; Islamgaliev, R.K.; Valiev, R.Z.; Zhu, Y.T.

2016-01-01

Different with common grain refinement dominated by dislocation activities, grain subdivision induced by sequential activation of multiple twinning was observed in a Mg-Gd-Y-Zr magnesium alloy via high-pressure torsion. Deformation bands were evolved from large primary twin bands, which contained refined grains through localized multiple twinning. Nanometer-scaled amorphous bands were also observed within deformation bands in Mg alloys for the first time. These observations indicate that localized deformation via multiple twinning and the consequent formation of deformation bands are potential routes to grain refinement in rare earth-magnesium alloys.

Updated results of high-dose rate brachytherapy and external beam radiotherapy for locally and locally advanced prostate cancer using the RTOG-ASTRO phoenix definition

Directory of Open Access Journals (Sweden)

Antonio C. Pellizzon

2008-06-01

Full Text Available PURPOSE: To evaluate the prognostic factors for patients with local or locally advanced prostate cancer treated with external beam radiotherapy (RT and high dose rate brachytherapy (HDR according to the RTOG-ASTRO Phoenix Consensus Conference. MATERIALS AND METHODS: The charts of 209 patients treated between 1997 and 2005 with localized RT and HDR as a boost at the Department of Radiation Oncology, AC Camargo Hospital, Sao Paulo, Brazil were reviewed. Clinical and treatment parameters i.e.: patient's age, Gleason score, clinical stage, initial PSA (iPSA, risk group (RG for biochemical failure, doses of RT and HDR were evaluated. Median age and median follow-up time were 68 and 5.3 years, respectively. Median RT and HDR doses were 45 Gy and 20 Gy. RESULTS: Disease specific survival (DSS at 3.3 year was 94.2%. Regarding RG, for the LR (low risk, IR (intermediate risk and HR (high risk, the DSS rates at 3.3 years were 91.5%, 90.2% and 88.5%, respectively. On univariate analysis prognostic factors related to DSS were RG (p = 0.040, Gleason score ≤ 6 ng/mL (p = 0.002, total dose of HDR ≥ 20 Gy (p < 0.001 On multivariate analysis the only statistical significant predictive factor for biochemical control (bNED was the RG, p < 0.001 (CI - 1.147-3.561. CONCLUSIONS: Although the radiation dose administered to the prostate is an important factor related to bNED, this could not be established with statistical significance in this group of patients. To date , in our own experience, HDR associated to RT could be considered a successful approach in the treatment of prostate cancer.

Advances and perspectives in bathymetry by airborne lidar

Science.gov (United States)

Zhou, Guoqing; Wang, Chenxi; Li, Mingyan; Wang, Yuefeng; Ye, Siqi; Han, Caiyun

2015-12-01

In this paper, the history of the airborne lidar and the development stages of the technology are reviewed. The basic principle of airborne lidar and the method of processing point-cloud data were discussed. At present, single point laser scanning method is widely used in bathymetric survey. Although the method has high ranging accuracy, the data processing and hardware system is too much complicated and expensive. For this reason, this paper present a kind of improved dual-frequency method for bathymetric and sea surface survey, in this method 176 units of 1064nm wavelength laser has been used by push-broom scanning and due to the airborne power limits still use 532nm wavelength single point for bathymetric survey by zigzag scanning. We establish a spatial coordinates for obtaining the WGS-84 of point cloud by using airborne POS system.

Local variability in growth and reproduction of Salix arctica in the High Arctic

Directory of Open Access Journals (Sweden)

Noémie Boulanger-Lapointe

2016-06-01

Full Text Available Arctic terrestrial ecosystems are heterogeneous because of the strong influences of microtopography, soil moisture and snow accumulation on vegetation distribution. The interaction between local biotic and abiotic factors and global climate patterns will influence species responses to climate change. Salix arctica (Arctic willow is a structuring species, ubiquitous and widespread, and as such is one of the most important shrub species in the High Arctic. In this study, we measured S. arctica reproductive effort, early establishment, survival and growth in the Zackenberg valley, north-east Greenland. We sampled four plant communities that varied with respect to snow conditions, soil moisture, nutrient content and plant composition. We found large variability in reproductive effort and success with total catkin density ranging from 0.6 to 66 catkins/m2 and seedling density from <1 to 101 seedlings/m2. There were also major differences in crown area increment (4–23 cm2/year and stem radial growth (40–74 µm/year. The snowbed community, which experienced a recent reduction in snow cover, supported young populations with high reproductive effort, establishment and growth. Soil nutrient content and herbivore activity apparently did not strongly constrain plant reproduction and growth, but competition by Cassiope tetragona and low soil moisture may inhibit performance. Our results show that local environmental factors, such as snow accumulation, have a significant impact on tundra plant response to climate change and will affect the understanding of regional vegetation response to climate change.

The seismogenic zone in the Central Costa Rican Pacific margin: high-quality hypocentres from an amphibious network

Science.gov (United States)

Arroyo, Ivonne G.; Husen, Stephan; Flueh, Ernst R.

2014-10-01

Transition from subduction of normal to thickened oceanic crust occurs in the central portion of the Costa Rican margin, where large interplate earthquakes ( M ~ 7) and abundant interseismic seismicity have been associated with subduction of bathymetric highs. We relocated ~1,300 earthquakes recorded for 6 months by a combined on- and offshore seismological network using probabilistic earthquake relocation in a 3D P-wave velocity model. Most of the seismicity originated at the seismogenic zone of the plate boundary, appearing as an 18° dipping, planar cluster from 15 to 25-30 km depth, beneath the continental shelf. Several reverse focal mechanisms were resolved within the cluster. The upper limit of this interseismic interplate seismicity seems to be controlled primarily by the overlying-plate thickness and coherency, which in turn is governed by the erosional processes and fluid release and escape at temperatures lower than ~100 to 120 °C along the plate boundary. The downdip limit of the stick-slip behaviour collocates with relative low temperatures of ~150 to 200 °C, suggesting that it is controlled by serpentinization of the mantle wedge. The distribution of the interseismic interplate seismicity is locally modified by the presence of subducted seamounts at different depths. Unlike in northern Costa Rica, rupture of large earthquakes in the last two decades seems to coincide with the area defined by the interseismic interplate seismicity.

High-Dose-Rate Monotherapy: Safe and Effective Brachytherapy for Patients With Localized Prostate Cancer

International Nuclear Information System (INIS)

Demanes, D. Jeffrey; Martinez, Alvaro A.; Ghilezan, Michel; Hill, Dennis R.; Schour, Lionel; Brandt, David; Gustafson, Gary

2011-01-01

Purpose: High-dose-rate (HDR) brachytherapy used as the only treatment (monotherapy) for early prostate cancer is consistent with current concepts in prostate radiobiology, and the dose is reliably delivered in a prospectively defined anatomic distribution that meets all the requirements for safe and effective therapy. We report the disease control and toxicity of HDR monotherapy from California Endocurietherapy (CET) and William Beaumont Hospital (WBH) in low- and intermediate-risk prostate cancer patients. Methods and Materials: There were 298 patients with localized prostate cancer treated with HDR monotherapy between 1996 and 2005. Two biologically equivalent hypofractionation protocols were used. At CET the dose was 42 Gy in six fractions (two implantations 1 week apart) delivered to a computed tomography–defined planning treatment volume. At WBH the dose was 38 Gy in four fractions (one implantation) based on intraoperative transrectal ultrasound real-time treatment planning. The bladder, urethral, and rectal dose constraints were similar. Toxicity was scored with the National Cancer Institute Common Toxicity Criteria for Adverse Events version 3. Results: The median follow-up time was 5.2 years. The median age of the patients was 63 years, and the median value of the pretreatment prostate-specific antigen was 6.0 ng/mL. The 8-year results were 99% local control, 97% biochemical control (nadir +2), 99% distant metastasis–free survival, 99% cause-specific survival, and 95% overall survival. Toxicity was scored per event, meaning that an individual patient with more than one symptom was represented repeatedly in the morbidity data table. Genitourinary toxicity consisted of 10% transient Grade 2 urinary frequency or urgency and 3% Grade 3 episode of urinary retention. Gastrointestinal toxicity was <1%. Conclusions: High disease control rates and low morbidity demonstrate that HDR monotherapy is safe and effective for patients with localized prostate cancer.

High spatial resolution mapping of water quality and bathymetry with an autonomous underwater vehicle

Science.gov (United States)

Pampalone, Vincenzo; Milici, Barbara

2015-12-01

The drone Ecomapper AUV (Autonomous Underwater Vehicle) is a rare example of highly technological instrument in the environmental coastal monitoring field. The YSI EcoMapper is a one-man deployable, Autonomous Underwater Vehicle (AUV) designed to collect bathymetry and water quality data. The submarine-like vehicle follows a programmed course and employs sensors mounted in the nose to record pertinent information. Once the vehicle has started its mission, it operates independently of the user and utilizes GPS waypoints navigation to complete its programmed course. Throughout the course, the vehicle constantly steers toward the line drawn in the mission planning software (VectorMap), essentially following a more accurate road of coordinates instead of transversing waypoint-to-waypoint. It has been equipped with a Doppler Velocity Log (DVL) to increase its underwater navigation accuracy. Potential EcoMapper applications include baseline environmental mapping in freshwater, estuarine or near-coastal environments, bathymetric mapping, dissolved oxygen studies, event monitoring (algal blooms, storm impacts, low dissolved oxygen), non-point source studies, point-source dispersion mapping, security, search & rescue, inspection, shallow water mapping, thermal dissipation mapping of cooling outfalls, trace-dye studies. The AUV is used in the coastal area of the Augusta Bay (Italy), located in the eastern part of Sicily. Due to the heavy contamination generated by the several chemical and petrochemical industries active in the zone, the harbour was declared a Contaminated Site of National Interest. The ecomapper allows for a simultaneous data collection of water quality and bathymetric data providing a complete environmental mapping system of the Harbour.

Bathymetric and geographic population structure in the pan-Atlantic deep-sea bivalve Deminucula atacellana (Schenck, 1939).

Science.gov (United States)

Zardus, John D; Etter, Ron J; Chase, Michael R; Rex, Michael A; Boyle, Elizabeth E

2006-03-01

The deep-sea soft-sediment environment hosts a diverse and highly endemic fauna of uncertain origin. We know little about how this fauna evolved because geographic patterns of genetic variation, the essential information for inferring patterns of population differentiation and speciation are poorly understood. Using formalin-fixed specimens from archival collections, we quantify patterns of genetic variation in the protobranch bivalve Deminucula atacellana, a species widespread throughout the Atlantic Ocean at bathyal and abyssal depths. Samples were taken from 18 localities in the North American, West European and Argentine basins. A hypervariable region of mitochondrial 16S rDNA was amplified by polymerase chain reaction (PCR) and sequenced from 130 individuals revealing 21 haplotypes. Except for several important exceptions, haplotypes are unique to each basin. Overall gene diversity is high (h = 0.73) with pronounced population structure (Phi(ST) = 0.877) and highly significant geographic associations (P < 0.0001). Sequences cluster into four major clades corresponding to differences in geography and depth. Genetic divergence was much greater among populations at different depths within the same basin, than among those at similar depths but separated by thousands of kilometres. Isolation by distance probably explains much of the interbasin variation. Depth-related divergence may reflect historical patterns of colonization or strong environmental selective gradients. Broadly distributed deep-sea organisms can possess highly genetically divergent populations, despite the lack of any morphological divergence.

Collaboration with a local organization on the subjects of energy/radiation field in high school science education

International Nuclear Information System (INIS)

Suzuki, Takahiro; Mori, Chizuo

2005-01-01

We, high school teachers, collaborated with a local organization, Chubu Atomic Power Conference (partly in co-operation with The Radiation Education Forum), in the education on the subjects of energy and radiation fields. In addition to the subjects concerned with radiations, cloud chamber and personal radiation-monitor, we developed a few new subjects, which are not directly connected themselves with radiations, for the purpose to widen the fields and to bring the high acceptability of the subjects in high school side. (author)

Developing Local Scale, High Resolution, Data to Interface with Numerical Storm Models

Science.gov (United States)

Witkop, R.; Becker, A.; Stempel, P.

2017-12-01

High resolution, physical storm models that can rapidly predict storm surge, inundation, rainfall, wind velocity and wave height at the intra-facility scale for any storm affecting Rhode Island have been developed by Researchers at the University of Rhode Island's (URI's) Graduate School of Oceanography (GSO) (Ginis et al., 2017). At the same time, URI's Marine Affairs Department has developed methods that inhere individual geographic points into GSO's models and enable the models to accurately incorporate local scale, high resolution data (Stempel et al., 2017). This combination allows URI's storm models to predict any storm's impacts on individual Rhode Island facilities in near real time. The research presented here determines how a coastal Rhode Island town's critical facility managers (FMs) perceive their assets as being vulnerable to quantifiable hurricane-related forces at the individual facility scale and explores methods to elicit this information from FMs in a format usable for incorporation into URI's storm models.

KINEMATIC CLASSIFICATIONS OF LOCAL INTERACTING GALAXIES: IMPLICATIONS FOR THE MERGER/DISK CLASSIFICATIONS AT HIGH-z

International Nuclear Information System (INIS)

Hung, Chao-Ling; Larson, Kirsten L.; Sanders, D. B.; Rich, Jeffrey A.; Yuan, Tiantian; Kewley, Lisa J.; Casey, Caitlin M.; Smith, Howard A.; Hayward, Christopher C.

2015-01-01

The classification of galaxy mergers and isolated disks is key for understanding the relative importance of galaxy interactions and secular evolution during the assembly of galaxies. Galaxy kinematics as traced by emission lines have been used to suggest the existence of a significant population of high-z star-forming galaxies consistent with isolated rotating disks. However, recent studies have cautioned that post-coalescence mergers may also display disk-like kinematics. To further investigate the robustness of merger/disk classifications based on kinematic properties, we carry out a systematic classification of 24 local (U)LIRGs spanning a range of morphologies: from isolated spiral galaxies, ongoing interacting systems, to fully merged remnants. We artificially redshift the Wide Field Spectrograph observations of these local (U)LIRGs to z = 1.5 to make a realistic comparison with observations at high-z, and also to ensure that all galaxies have the same spatial sampling of ∼900 pc. Using both kinemetry-based and visual classifications, we find that the reliability of kinematic classification shows a strong trend with the interaction stage of galaxies. Mergers with two nuclei and tidal tails have the most distinct kinematics compared to isolated disks, whereas a significant population of the interacting disks and merger remnants are indistinguishable from isolated disks. The high fraction of mergers displaying disk-like kinematics reflects the complexity of the dynamics during galaxy interactions. Additional merger indicators such as morphological properties traced by stars or molecular gas are required to further constrain the merger/disk classifications at high-z

Built-Up Area Detection from High-Resolution Satellite Images Using Multi-Scale Wavelet Transform and Local Spatial Statistics

Science.gov (United States)

Chen, Y.; Zhang, Y.; Gao, J.; Yuan, Y.; Lv, Z.

2018-04-01

Recently, built-up area detection from high-resolution satellite images (HRSI) has attracted increasing attention because HRSI can provide more detailed object information. In this paper, multi-resolution wavelet transform and local spatial autocorrelation statistic are introduced to model the spatial patterns of built-up areas. First, the input image is decomposed into high- and low-frequency subbands by wavelet transform at three levels. Then the high-frequency detail information in three directions (horizontal, vertical and diagonal) are extracted followed by a maximization operation to integrate the information in all directions. Afterward, a cross-scale operation is implemented to fuse different levels of information. Finally, local spatial autocorrelation statistic is introduced to enhance the saliency of built-up features and an adaptive threshold algorithm is used to achieve the detection of built-up areas. Experiments are conducted on ZY-3 and Quickbird panchromatic satellite images, and the results show that the proposed method is very effective for built-up area detection.

Ultra-compact high velocity clouds in the ALFALFA HI survey: Candidate Local Group galaxies?

Science.gov (United States)

Adams, Elizabeth Ann Kovenz

The increased sensitivity and spatial resolution of the ALFALFA HI survey has resulted in the detection of ultra-compact high velocity clouds (UCHVCs). These objects are good candidates to represent low mass gas-rich galaxies in the Local Group and Local Volume with stellar populations that are too faint to be detected in extant optical surveys. This idea is referred to as the "minihalo hypothesis". We identify the UCHVCs within the ALFALFA dataset via the use of a 3D matched filtering signal identification algorithm. UCHVCs are selected based on a compact size ( 120 km s-1) and isolation. Within the 40% complete ALFALFA survey (alpha.40), 59 UCHVCs are identified; 19 are in a most-isolated subset and are the best galaxy candidates. Due to the presence of large HVC complexes in the fall sky, most notably the Magellanic Stream, the association of UCHVCs with existing structure cannot be ruled out. In the spring sky, the spatial and kinematic distribution of the UCHVCs is consistent with simulations of dark matter halos within the Local Group. In addition, the HI properties of the UCHVCs (if placed at 1 Mpc) are consistent with both theoretical and observational predictions for low mass gas-rich galaxies. Importantly, the HI properties of the UCHVCs are consistent with those of two recently discovered low mass gas-rich galaxies in the Local Group and Local Volume, Leo T and Leo P. Detailed follow-up observations are key for addressing the minihalo hypothesis. High resolution HI observations can constrain the environment of a UCHVC and offer evidence for a hosting dark matter halo through evidence of rotation support and comparison to theoretical models. Observations of one UCHVC at high resolution (15'') reveal the presence of a clumpy HI distribution, similar to both low mass galaxies and circumgalactic compact HVCs. An extended envelope containing ˜50% of the HI flux is resolved out by the array configuration; observations at lower spatial resolution can recover

TOPOGRAPHIC LOCAL ROUGHNESS EXTRACTION AND CALIBRATION OVER MARTIAN SURFACE BY VERY HIGH RESOLUTION STEREO ANALYSIS AND MULTI SENSOR DATA FUSION

Directory of Open Access Journals (Sweden)

J. R. Kim

2012-08-01

Full Text Available The planetary topography has been the main focus of the in-orbital remote sensing. In spite of the recent development in active and passive sensing technologies to reconstruct three dimensional planetary topography, the resolution limit of range measurement is theoretically and practically obvious. Therefore, the extraction of inner topographical height variation within a measurement spot is very challengeable and beneficial topic for the many application fields such as the identification of landform, Aeolian process analysis and the risk assessment of planetary lander. In this study we tried to extract the topographic height variation over martian surface so called local roughness with different approaches. One method is the employment of laser beam broadening effect and the other is the multi angle optical imaging. Especially, in both cases, the precise pre processing employing high accuracy DTM (Digital Terrain Model were introduced to minimise the possible errors. Since a processing routine to extract very high resolution DTMs up to 0.5–4m grid-spacing from HiRISE (High Resolution Imaging Science Experiment and 20–10m DTM from CTX (Context Camera stereo pair has been developed, it is now possible to calibrate the local roughness compared with the calculated height variation from very high resolution topographic products. Three testing areas were chosen and processed to extract local roughness with the co-registered multi sensor data sets. Even though, the extracted local roughness products are still showing the strong correlation with the topographic slopes, we demonstrated the potentials of the height variations extraction and calibration methods.

High-dose rate intra-operative radiation therapy for local advanced and recurrent colorectal cancer

International Nuclear Information System (INIS)

Harrison, L.B.; Mychalczak, B.; Enker, W.; Anderson, L.; Cohen, A.E.; Minsky, B.

1996-01-01

In an effort to improve the local control for advanced and recurrent cancers of the rectum, we have integrated high-dose rate intra-operative radiation therapy (HDR-IORT) into the treatment program. Between 11/92 and 10/95, 47 patients (pts) were treated. There were 26 males and 21 females whose ages ranged from 30-80 (median = 62) years. There were 19 pts with primary unresectable rectal cancer, and 28 pts who were treated for recurrent rectal cancer. Histology was adenocarcinoma - 45 pts, squamous cancer - 2 pts. The range of follow-up is 1-34 months (median = 14 months). The majority of primary unresectable pts received pre-operative radiation therapy (4500-5040 cGy) with chemotherapy (5-FU with Leucovorin) 4-6 weeks later, they underwent resection + HDR-IORT (1200 cGy). For the 28 pts with recurrent cancer, the majority received surgery and HDR-IORT alone because they had received prior RT. For the pts with primary unresectable disease, actuarial 2-year local control was 77%, actuarial distant metastasis-free survival was 71%, disease free survival was 66%, and overall survival was 84%. For those pts with recurrent disease, actuarial 2-year local control rate was 65%, distant metastasis-free survival was 65%, disease free survival was 47%, and overall survival was 61%. Complications occurred in 36%. There were no cases where the anatomical distribution of disease, or technical limitations prevented the adequate delivery of HDR-IORT. We conclude that this technique was most versatile, and enabled all appropriate pts to receive IORT. The preliminary data in terms of local control are encouraging, even for the poor prognostic sub-group of pts with recurrent cancer

Local adaptation despite high gene flow in the waterfall-climbing Hawaiian goby, Sicyopterus stimpsoni.

Science.gov (United States)

Moody, K N; Hunter, S N; Childress, M J; Blob, R W; Schoenfuss, H L; Blum, M J; Ptacek, M B

2015-02-01

Environmental heterogeneity can promote the emergence of locally adapted phenotypes among subpopulations of a species, whereas gene flow can result in phenotypic and genotypic homogenization. For organisms like amphidromous fishes that change habitats during their life history, the balance between selection and migration can shift through ontogeny, making the likelihood of local adaptation difficult to predict. In Hawaiian waterfall-climbing gobies, it has been hypothesized that larval mixing during oceanic dispersal counters local adaptation to contrasting topographic features of streams, like slope gradient, that can select for predator avoidance or climbing ability in juvenile recruits. To test this hypothesis, we used morphological traits and neutral genetic markers to compare phenotypic and genotypic distributions in recruiting juveniles and adult subpopulations of the waterfall-climbing amphidromous goby, Sicyopterus stimpsoni, from the islands of Hawai'i and Kaua'i. We found that body shape is significantly different between adult subpopulations from streams with contrasting slopes and that trait divergence in recruiting juveniles tracked stream topography more so than morphological measures of adult subpopulation differentiation. Although no evidence of population genetic differentiation was observed among adult subpopulations, we observed low but significant levels of spatially and temporally variable genetic differentiation among juvenile cohorts, which correlated with morphological divergence. Such a pattern of genetic differentiation is consistent with chaotic genetic patchiness arising from variable sources of recruits to different streams. Thus, at least in S. stimpsoni, the combination of variation in settlement cohorts in space and time coupled with strong postsettlement selection on juveniles as they migrate upstream to adult habitats provides the opportunity for morphological adaptation to local stream environments despite high gene flow. © 2014

Temperature Dependence of Charge Localization in High-Mobility, Solution-Crystallized Small Molecule Semiconductors Studied by Charge Modulation Spectroscopy

DEFF Research Database (Denmark)

Meneau, Aurélie Y. B.; Olivier, Yoann; Backlund, Tomas

2016-01-01

In solution-processable small molecule semiconductors, the extent of charge carrier wavefunction localization induced by dynamic disorder can be probed spectroscopically as a function of temperature using charge modulation spectroscopy (CMS). Here, it is shown based on combined fi eld-effect tran......In solution-processable small molecule semiconductors, the extent of charge carrier wavefunction localization induced by dynamic disorder can be probed spectroscopically as a function of temperature using charge modulation spectroscopy (CMS). Here, it is shown based on combined fi eld......-effect transistor and CMS measurements as a function of temperature that in certain molecular semiconductors, such as solution-processible pentacene, charge carriers become trapped at low temperatures in environments in which the charges become highly localized on individual molecules, while in some other molecules...

Early and late effects of local high dose radiotherapy of the brain on memory and attention

International Nuclear Information System (INIS)

Duchstein, S.; Gademann, G.; Peters, B.

2003-01-01

Early and Late Effects of Local High Dose Radiotherapy of the Brain on Memory and Attention Background: Stereotactic radiotherapy of benign tumors of the base of skull shows excellent tumor control and long survival. Aim is to study the impact of high dose radiation therapy on functions of memory and attention over time. Patients and Methods: 21 patients (age 42 ± 11 years) with tumors of the base of skull (meningiomas, pituitary gland adenomas) were treated by fractionated stereotactic radiotherapy (mean total dose 56,6 Gy/1,8 Gy). Comprehensive neuropsychological tests and MRI brain scans were performed before, 3, 9 and 21 months after therapy. 14 healthy volunteers were tested in parallel at baseline. In the follow-ups patients were their own controls. Results: In pretreatment tests there were significantly worse test results in comparison to the control group in ten of 32 tests. In postradiation tests only few changes were found in the early-delayed period and not much difference was seen in comparison to the baseline tests. In MRI scans tumor recurrences or radiation induced changes were not found. Conclusion: Radiation with high local doses in target volume extremely close to sensitive brain structures like temporal lobes did not induce significant decline of cognitive functions. (orig.) [de

Genomic signatures of local directional selection in a high gene flow marine organism, the Atlantic cod (Gadus morhua)

DEFF Research Database (Denmark)

Eg Nielsen, Einar; Hansen, Jakob Hemmer; Poulsen, Nina Aagaard

2009-01-01

-associated single nucleotide polymorphisms (SNPs) for evidence of selection in local populations of Atlantic cod (Gadus morhua L.) across the species distribution. Results: Our global genome scan analysis identified eight outlier gene loci with very high statistical support, likely to be subject to directional...... selection in local demes, or closely linked to loci under selection. Likewise, on a regional south/north transect of central and eastern Atlantic populations, seven loci displayed strongly elevated levels of genetic differentiation. Selection patterns among populations appeared to be relatively widespread...

High-resolution biosensor based on localized surface plasmons

Czech Academy of Sciences Publication Activity Database

Piliarik, Marek; Šípová, Hana; Kvasnička, Pavel; Galler, N.; Krenn, J. R.; Homola, Jiří

2012-01-01

Roč. 20, č. 1 (2012), s. 672-680 ISSN 1094-4087 R&D Projects: GA AV ČR KAN200670701; GA MŠk OC09058 Institutional research plan: CEZ:AV0Z20670512 Keywords : optical biosenzor * surface plasmon resonance * localized surface plasmon Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 3.546, year: 2012

Local wall thickness reductions in operative high-pressure gas pipelines; Lokale Wanddickenminderungen an in Betrieb befindlichen Gashochdruckleitungen

Energy Technology Data Exchange (ETDEWEB)

Hass, Georg [Netzdienste Rhein-Main GmbH, Frankfurt am Main (Germany); Hoffmann, Ulrich [Verbundnetz Gas AG (VNG), Leipzig (Germany); Konarske, Juergen [RWE Westfalen-Weser-Ems Netzservice GmbH, Recklinghausen (Germany); Soppa, Thorsten [NG Netz Gas+Wasser (Germany); Steiner, Michael [Open Grid Europe GmbH, Essen (Germany)

2011-04-15

TUeV Nord, Salzgitter Mannesmann Forschung and DVGW investigated methods to assess local wall thickness reductions in operative high-pressure gas pipelines. Methods described in the relevant literature were reviewed with regard to the limiting criteria defined for maximum permissible wall thickness reductions. (orig./GL)

Paleographical, Bathymetric and Numerical Investigations for a Tsunami Possibly Caused by Submarine Mass Failure in the Nankai Trough, Japan

Science.gov (United States)

Baba, T.; Ashi, J.; Kanamatsu, T.; Imai, K.; Yamashita, K.

2017-12-01

"SHINCHO-KI" is an ancient document that records tsunami damages caused by the 1512 Eisho earthquake, the 1605 Keicho earthquake, the 1707 Hoei earthquake and the 1854 Ansei-Nankai earthquake in Shishikui, where is located along the coast of the southeastern part of Shikoku, facing to the Nankai trough. According to SHINCHO-KI, 3700 people were dead in Shishikui by the tsunami during the 1512 Eisho earthquake. However, no evidence was found for the occurrence of the 1512 Eisho earthquake except for SHINCHO-KI, while the other earthquakes were recorded in many ancient documents in the southwestern Japan. To investigate the source mechanism of the 1512 Eisho earthquake, we carefully read a bathymetric chart and found a scarp with a height of about 400 m and a width of about 6000 m at a position about 24 km offshore in the southeastern direction from Shishikui. We also carried out a survey by using a deep-towed sub-bottom profiler (SBP) on ROV NSS during the R/V Hakuho-maru KH-16-5 cruise. The result shows detailed structures possibly caused by a recent landslide. The vertical displacement of the strata was measured to be about 50 m. By considering these results, we simulated the 1512 Eisho tsunami generated by a submarine mass failure. The topographic data in Shishikui which is needed in the calculation was made from the present data. But we removed the artificial structures such as wave breakers and altered coastlines by referring to old map images. In the numerical simulation, the initial sea surface deformation was obtained by the method proposed by Watts et al. (2005), and the tsunami propagation was calculated by solving the nonlinear shallow water equations with dispersive (Boussinesq) term on a finite difference scheme. We solved the advection terms by using the third-order upwind difference to avoid artificial viscosity. The numerical simulation estimated the maximum tsunami height of about 6m and moderate inundation on land in Shishikui by the 1512 Eisho

High-conductance low-voltage organic thin film transistor with locally rearranged poly(3-hexylthiophene) domain by current annealing on plastic substrate

Science.gov (United States)

Pei, Zingway; Tsai, Hsing-Wang; Lai, Hsin-Cheng

2016-02-01

The organic material based thin film transistors (TFTs) are attractive for flexible optoelectronics applications due to the ability of lager area fabrication by solution and low temperature process on plastic substrate. Recently, the research of organic TFT focus on low operation voltage and high output current to achieve a low power organic logic circuit for optoelectronic device,such as e-paper or OLED displayer. To obtain low voltage and high output current, high gate capacitance and high channel mobility are key factors. The well-arranged polymer chain by a high temperature postannealing, leading enhancement conductivity of polymer film was a general method. However, the thermal annealing applying heat for all device on the substrate and may not applicable to plastic substrate. Therefore, in this work, the low operation voltage and high output current of polymer TFTs was demonstrated by locally electrical bias annealing. The poly(styrene-comethyl methacrylate) (PS-r-PMMA) with ultra-thin thickness is used as gate dielectric that the thickness is controlled by thermal treatment after spin coated on organic electrode. In electrical bias-annealing process, the PS-r- PMMA is acted a heating layer. After electrical bias-annealing, the polymer TFTs obtain high channel mobility at low voltage that lead high output current by a locally annealing of P3HT film. In the future, the locally electrical biasannealing method could be applied on plastic substrate for flexible optoelectronic application.

A short discussion on artifact creating conditions using multibeam bathymetric systems in a highly reflecting and smooth bottom

Digital Repository Service at National Institute of Oceanography (India)

Chakraborty, B.

Using multibeam system, artifact creating conditions are dominant when functioning in highly reflective and flat bottom areas. This simulation study manifests the causes responsible for creating such conditions which influence seafloor...

A global, high-resolution data set of ice sheet topography, cavity geometry, and ocean bathymetry

Science.gov (United States)

Schaffer, Janin; Timmermann, Ralph; Arndt, Jan Erik; Savstrup Kristensen, Steen; Mayer, Christoph; Morlighem, Mathieu; Steinhage, Daniel

2016-10-01

The ocean plays an important role in modulating the mass balance of the polar ice sheets by interacting with the ice shelves in Antarctica and with the marine-terminating outlet glaciers in Greenland. Given that the flux of warm water onto the continental shelf and into the sub-ice cavities is steered by complex bathymetry, a detailed topography data set is an essential ingredient for models that address ice-ocean interaction. We followed the spirit of the global RTopo-1 data set and compiled consistent maps of global ocean bathymetry, upper and lower ice surface topographies, and global surface height on a spherical grid with now 30 arcsec grid spacing. For this new data set, called RTopo-2, we used the General Bathymetric Chart of the Oceans (GEBCO_2014) as the backbone and added the International Bathymetric Chart of the Arctic Ocean version 3 (IBCAOv3) and the International Bathymetric Chart of the Southern Ocean (IBCSO) version 1. While RTopo-1 primarily aimed at a good and consistent representation of the Antarctic ice sheet, ice shelves, and sub-ice cavities, RTopo-2 now also contains ice topographies of the Greenland ice sheet and outlet glaciers. In particular, we aimed at a good representation of the fjord and shelf bathymetry surrounding the Greenland continent. We modified data from earlier gridded products in the areas of Petermann Glacier, Hagen Bræ, and Sermilik Fjord, assuming that sub-ice and fjord bathymetries roughly follow plausible Last Glacial Maximum ice flow patterns. For the continental shelf off Northeast Greenland and the floating ice tongue of Nioghalvfjerdsfjorden Glacier at about 79° N, we incorporated a high-resolution digital bathymetry model considering original multibeam survey data for the region. Radar data for surface topographies of the floating ice tongues of Nioghalvfjerdsfjorden Glacier and Zachariæ Isstrøm have been obtained from the data centres of Technical University of Denmark (DTU), Operation Icebridge (NASA

Defense Coastal/Estuarine Research Program 2 (DCERP2)

Science.gov (United States)

2013-05-01

Assessing TMDL effectiveness using flow-adjusted concentrations:  A case study of the Neuse River , North Carolina. Environmental Science & Technology 37...activities, and data collection in the NRE Basin and New River by local stakeholder groups. Defense Coastal/Estuarine Research Program (DCERP) Monitoring...relationships between light penetration and solids/chl a levels. ArcGIS and spatial statistics will be used to estimate average bathymetric areas

Knock-down of a tonoplast localized low-affinity nitrate transporter OsNPF7.2 affects rice growth under high nitrate ssupply

Directory of Open Access Journals (Sweden)

Rui Hu

2016-10-01

Full Text Available The large nitrate transporter 1/peptide transporter family (NPF has been shown to transport diverse substrates, including nitrate, amino acids, peptides, phytohormones, and glucosinolates. However, the rice (Oryza sativa root-specific expressed member OsNPF7.2 has not been characterized. Here, our data show that OsNPF7.2 is a tonoplast localized low-affinity nitrate transporter, and affects rice growth under high nitrate supply. The expression analysis showed that OsNPF7.2 was mainly expressed in the elongation and maturation zones of roots, especially in the root sclerenchyma, cortex and stele. It was also induced by high concentrations of nitrate. Subcellular localization analysis showed that OsNPF7.2 was localized on the tonoplast of large and small vacuoles. Heterogenous expression in Xenopus laevis oocytes suggested that OsNPF7.2 was a low-affinity nitrate transporter. Knock-down of OsNPF7.2 retarded rice growth under high concentrations of nitrate. Therefore, we deduce that OsNPF7.2 plays a role in intracellular allocation of nitrate in roots, and thus influences rice growth under high nitrate supply.

A possibility of local measurements of ion temperature in a high-temperature plasma by laser induced ionization

International Nuclear Information System (INIS)

Kantor, M

2012-01-01

A new diagnostic for local measurements of ion temperature and drift velocity in fusion plasmas is proposed in the paper. The diagnostic is based on laser induced ionization of excited hydrogen and deuterium atoms from the levels which ionization energy less than the laser photon energy. A high intensive laser beam ionizes nearly all the excited atoms in the beam region resulting in a quench of spontaneous line emission of the appropriate optical transitions. The measurements of the quenching emission have been used in the past for local measurements of hydrogen atom density in tokamak plasma. The idea of the new diagnostic is spectral resolution of the quenching emission. The measured spectrum relates directly to the velocity distribution of the excited atoms. This distribution is strongly coupled to the distribution of the hydrogen atoms at the ground state. So, the spectral resolution of quenching emission is a way of local measurements of the temperature and drift velocity of hydrogen atoms in plasma. The temperature of hydrogen atoms is well coupled to the local ion temperature as long as the mean free path of the atoms is shorter than the ion gradient length in plasma. In this case the new diagnostic can provide local measurements of ion temperature in plasma. The paper considers technical capabilities of the diagnostic, physical restrictions of its application and interpretation of the measurements.

An Efficient Local Correlation Matrix Decomposition Approach for the Localization Implementation of Ensemble-Based Assimilation Methods

Science.gov (United States)

Zhang, Hongqin; Tian, Xiangjun

2018-04-01

Ensemble-based data assimilation methods often use the so-called localization scheme to improve the representation of the ensemble background error covariance (Be). Extensive research has been undertaken to reduce the computational cost of these methods by using the localized ensemble samples to localize Be by means of a direct decomposition of the local correlation matrix C. However, the computational costs of the direct decomposition of the local correlation matrix C are still extremely high due to its high dimension. In this paper, we propose an efficient local correlation matrix decomposition approach based on the concept of alternating directions. This approach is intended to avoid direct decomposition of the correlation matrix. Instead, we first decompose the correlation matrix into 1-D correlation matrices in the three coordinate directions, then construct their empirical orthogonal function decomposition at low resolution. This procedure is followed by the 1-D spline interpolation process to transform the above decompositions to the high-resolution grid. Finally, an efficient correlation matrix decomposition is achieved by computing the very similar Kronecker product. We conducted a series of comparison experiments to illustrate the validity and accuracy of the proposed local correlation matrix decomposition approach. The effectiveness of the proposed correlation matrix decomposition approach and its efficient localization implementation of the nonlinear least-squares four-dimensional variational assimilation are further demonstrated by several groups of numerical experiments based on the Advanced Research Weather Research and Forecasting model.

A high-resolution method for the localization of proanthocyanidins in plant tissues

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Panter Stephen

2011-05-01

Full Text Available Abstract Background Histochemical staining of plant tissues with 4-dimethylaminocinnamaldehyde (DMACA or vanillin-HCl is widely used to characterize spatial patterns of proanthocyanidin accumulation in plant tissues. These methods are limited in their ability to allow high-resolution imaging of proanthocyanidin deposits. Results Tissue embedding techniques were used in combination with DMACA staining to analyze the accumulation of proanthocyanidins in Lotus corniculatus (L. and Trifolium repens (L. tissues. Embedding of plant tissues in LR White or paraffin matrices, with or without DMACA staining, preserved the physical integrity of the plant tissues, allowing high-resolution imaging that facilitated cell-specific localization of proanthocyanidins. A brown coloration was seen in proanthocyanidin-producing cells when plant tissues were embedded without DMACA staining and this was likely to have been due to non-enzymatic oxidation of proanthocyanidins and the formation of colored semiquinones and quinones. Conclusions This paper presents a simple, high-resolution method for analysis of proanthocyanidin accumulation in organs, tissues and cells of two plant species with different patterns of proanthocyanidin accumulation, namely Lotus corniculatus (birdsfoot trefoil and Trifolium repens (white clover. This technique was used to characterize cell type-specific patterns of proanthocyanidin accumulation in white clover flowers at different stages of development.

Local vaginal anesthesia during high-dose-rate intracavitary brachytherapy for cervical cancer

International Nuclear Information System (INIS)

Chen, H.-C.; Wan Leung, Stephen; Wang, C.-J.; Sun, L.-M.; Fang, F.-M.; Huang, E.-Y.; Wang, S.-J.; Yang, C.-W.

1998-01-01

Purpose: To evaluate the clinical efficacy of local vaginal lidocaine application for pain relief during high-dose-rate (HDR) intracavitary brachytherapy for patients with cervical cancer, and to investigate sequential changes in serum levels of lidocaine during the procedures. Methods and Materials: This prospective study was designed to examine the analgesic effect, physical response, and side effects of local anesthesia during HDR intracavitary brachytherapy. Forty patients were enrolled. All patients received 10-15 MV X-rays to the pelvis with a total dose of 45-59.4 Gy 5-6 weeks before undergoing HDR intracavitary brachytherapy. All patients underwent first intracavitary brachytherapy under general anesthesia. These patients were randomly allocated to receive one of two different treatment protocols as follows: (1) treatment session - control session - treatment session - control session; or (2) control session - treatment session- control session - treatment session. In the treatment sessions, topical anesthesia was administered using 4 ml of 10% lidocaine solution sprayed liberally on the cervix and vagina during intracavitary brachytherapy. In the control sessions, a placebo was administered in the same manner during brachytherapy. The Hensche's applicators for brachytherapy were inserted into the cervix and vagina 5 min after lidocaine application. The visual analogue scale (VAS) was used to assess pain and discomfort during brachytherapy. Blood pressure and heart rates were measured to evaluate the physiological response. Another prospective study was then performed to investigate the sequential changes of serum lidocaine levels during the anesthetic procedure. Eleven additional patients with similar disease state and demographic characteristics were enrolled and blood samples were obtained before, and 5, 15, 30, and 45 min after the initiation of lidocaine application. Results: The mean VAS values recorded during the treatment sessions and control

High resolution CT for localization of early hilar lung carcinoma

International Nuclear Information System (INIS)

Minami, Yuko; Ishikawa, Shigemi; Saida, Yukihisa; Kajitani, Motomasa; Yamamoto, Tatsuo; Sato, Yukio; Onizuka, Masataka; Sakakibara, Yuzuru; Noguchi, Masayuki

2002-01-01

The purpose of this study was to analyse the usefulness of high resolution CT (HRCT) for the diagnosis and localization of roentgenographically occult lung cancer. HRCT was performed prospectively on chest X-ray negative patients with bloody sputum or suspicious or positive cells on sputum cytology between 1998 and 2000. After the HRCT scan, white light bronchoscopy and autofluorescence bronchoscopy were performed. HRCT depicted 19 hilar bronchial lesions in 13 cases out of 19 patients, of which 9 lesions were confirmed by white light broncoscope. Of 8 hilar squamous cell carcinomas diagnosed in this study, 7 lesions (87.5%) were depicted by HRCT. One CT-negative case (12.5%) was an in situ carcinoma in left B 1+2 . Four out of 20 lesions which showed bronchoscopic abnormality, could not be depicted by HRCT. HRCT could prospectively detect 80% of the bronchoscopic abnormalities and 87.5% of the hilar squamous cell carcinomas of the tracheobronchial lesions of the lung. Therefore, HRCT can be an effective supplemental means for screening for hilar squamous cell carcinoma. (author)

Polylysine as a vehicle for extracellular matrix-targeted local drug delivery, providing high accumulation and long-term retention within the vascular wall

NARCIS (Netherlands)

Sakharov, D.V.; Jie, A.F.H.; Bekkers, M.E.A.; Emeis, J.J.; Rijken, D.C.

2001-01-01

We present the first steps in the elaboration of an approach of extracellular matrix-targeted local drug delivery (ECM-LDD), designed to provide a high concentration, ubiquitous distribution, and long-term retention of a drug within the vessel wall after local intravascular delivery. The approach is

High performance computation of landscape genomic models including local indicators of spatial association.

Science.gov (United States)

Stucki, S; Orozco-terWengel, P; Forester, B R; Duruz, S; Colli, L; Masembe, C; Negrini, R; Landguth, E; Jones, M R; Bruford, M W; Taberlet, P; Joost, S

2017-09-01

With the increasing availability of both molecular and topo-climatic data, the main challenges facing landscape genomics - that is the combination of landscape ecology with population genomics - include processing large numbers of models and distinguishing between selection and demographic processes (e.g. population structure). Several methods address the latter, either by estimating a null model of population history or by simultaneously inferring environmental and demographic effects. Here we present samβada, an approach designed to study signatures of local adaptation, with special emphasis on high performance computing of large-scale genetic and environmental data sets. samβada identifies candidate loci using genotype-environment associations while also incorporating multivariate analyses to assess the effect of many environmental predictor variables. This enables the inclusion of explanatory variables representing population structure into the models to lower the occurrences of spurious genotype-environment associations. In addition, samβada calculates local indicators of spatial association for candidate loci to provide information on whether similar genotypes tend to cluster in space, which constitutes a useful indication of the possible kinship between individuals. To test the usefulness of this approach, we carried out a simulation study and analysed a data set from Ugandan cattle to detect signatures of local adaptation with samβada, bayenv, lfmm and an F ST outlier method (FDIST approach in arlequin) and compare their results. samβada - an open source software for Windows, Linux and Mac OS X available at http://lasig.epfl.ch/sambada - outperforms other approaches and better suits whole-genome sequence data processing. © 2016 The Authors. Molecular Ecology Resources Published by John Wiley & Sons Ltd.

High resolution modelling of aerosol dispersion regimes during the CAPITOUL field experiment: from regional to local scale interactions

Directory of Open Access Journals (Sweden)

B. Aouizerats

2011-08-01

Full Text Available High resolution simulation of complex aerosol particle evolution and gaseous chemistry over an atmospheric urban area is of great interest for understanding air quality and processes. In this context, the CAPITOUL (Canopy and Aerosol Particle Interactions in the Toulouse Urban Layer field experiment aims at a better understanding of the interactions between the urban dynamics and the aerosol plumes. During a two-day Intensive Observational Period, a numerical model experiment was set up to reproduce the spatial distribution of specific particle pollutants, from the regional scales and the interactions between different cities, to the local scales with specific turbulent structures. Observations show that local dynamics depends on the day-regime, and may lead to different mesoscale dynamical structures. This study focuses on reproducing these fine scale dynamical structures, and investigate the impact on the aerosol plume dispersion. The 500-m resolution simulation manages to reproduce convective rolls at local scale, which concentrate most of the aerosol particles and can locally affect the pollutant dispersion and air quality.

High-energy localized eigenstates in a Fabry-Perot graphene resonator in a magnetic field

Science.gov (United States)

Zalipaev, V. V.

2012-06-01

A semiclassical analysis of the high-energy eigenstates of Dirac fermions inside a graphene monolayer nanoribbon resonator of Fabry-Perot type in a magnetic field with zigzag boundary conditions is discussed. A semiclassical asymptotic method of construction of Maslov spectral series of energy spectrum and eigenfunctions, localized in an asymptotically small neighborhood of a periodic orbit, is developed for the graphene Dirac system. The isolated periodic orbit is confined between two flat boundaries. The analysis involves constructing a localized asymptotic solution to the Dirac system (electron-hole Gaussian beam). Then, the stability of a continuous family of periodic orbits (POs) confined between reflecting boundaries of the resonator is studied. The asymptotics of the eigenfunctions are constructed as a superposition of two Gaussian beams propagating in opposite directions between two reflecting points of the periodic orbit. The asymptotics of the energy spectrum are obtained by means of the generalized Bohr-Sommerfeld quantization condition only for stable POs. It provides two parts of semiclassical Maslov spectral series with positive and negative energies, for electrons and holes, correspondingly, with two different Hamiltonian dynamics and families of classical trajectories. The presence of electrostatic potential is vital as it makes a family of periodic orbit stable. For one subclass of lens-shaped periodic orbits, for a piecewise linear potential, localized eigenstates were computed numerically by the finite element method using COMSOL, and proved to be in very good agreement with the ones computed semiclassically.

A highly conserved Poc1 protein characterized in embryos of the hydrozoan Clytia hemisphaerica: localization and functional studies.

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Cécile Fourrage

Full Text Available Poc1 (Protein of Centriole 1 proteins are highly conserved WD40 domain-containing centriole components, well characterized in the alga Chlamydomonas, the ciliated protazoan Tetrahymena, the insect Drosophila and in vertebrate cells including Xenopus and zebrafish embryos. Functions and localizations related to the centriole and ciliary axoneme have been demonstrated for Poc1 in a range of species. The vertebrate Poc1 protein has also been reported to show an additional association with mitochondria, including enrichment in the specialized "germ plasm" region of Xenopus oocytes. We have identified and characterized a highly conserved Poc1 protein in the cnidarian Clytia hemisphaerica. Clytia Poc1 mRNA was found to be strongly expressed in eggs and early embryos, showing a punctate perinuclear localization in young oocytes. Fluorescence-tagged Poc1 proteins expressed in developing embryos showed strong localization to centrioles, including basal bodies. Anti-human Poc1 antibodies decorated mitochondria in Clytia, as reported in human cells, but failed to recognise endogenous or fluorescent-tagged Clytia Poc1. Injection of specific morpholino oligonucleotides into Clytia eggs prior to fertilization to repress Poc1 mRNA translation interfered with cell division from the blastula stage, likely corresponding to when neosynthesis normally takes over from maternally supplied protein. Cell cycle lengthening and arrest were observed, phenotypes consistent with an impaired centriolar biogenesis or function. The specificity of the defects could be demonstrated by injection of synthetic Poc1 mRNA, which restored normal development. We conclude that in Clytia embryos, Poc1 has an essentially centriolar localization and function.

Localization and Retrieval of an Eyelid Metallic Foreign Body With an Oscillating Magnet and High-Resolution Ultrasonography.

Science.gov (United States)

Yoo, Sylvia H; Rootman, Dan B; Goh, Alice; Savar, Aaron; Goldberg, Robert A

2016-01-01

A patient was found to have a metallic foreign body in the left anterior orbit on CT imaging, but the foreign body was not evident on clinical examination. On high-resolution ultrasonography, an object was identified in the left upper eyelid; however, the typical shadow with metallic foreign bodies was not seen. A high-power oscillating magnet was then applied to the eyelid, which revealed a subcutaneous metallic foreign body in the left upper eyelid. When used in conjunction, the high-resolution ultrasound and oscillating magnet successfully localized and facilitated retrieval of the metallic foreign body from the left upper eyelid.

Contemporary management of men with high-risk localized prostate cancer in the United States.

Science.gov (United States)

Weiner, A B; Matulewicz, R S; Schaeffer, E M; Liauw, S L; Feinglass, J M; Eggener, S E

2017-09-01

Surgery and radiation-based therapies are standard management options for men with clinically localized high-risk prostate cancer (PCa). Contemporary patterns of care are unknown. We hypothesize the use of surgery has steadily increased in more recent years. Using the National Cancer Data Base for 2004-2013, all men diagnosed with high-risk localized PCa were identified using National Comprehensive Cancer Network criteria. Temporal trends in initial management were assessed. Multivariable logistic regression was used to evaluate demographic and clinical factors associated with undergoing radical prostatectomy (RP). In total, 127 391 men were identified. Use of RP increased from 26% in 2004 to 42% in 2013 (adjusted risk ratio (RR) 1.51, 95% CI 1.42-1.60, P<0.001), while external beam radiation therapy (EBRT) decreased from 49% to 42% (P<0.001). African American men had lower odds of undergoing RP (unadjusted rate of 28%, adjusted RR 0.69, 95% CI 0.66-0.72, <0.001) compared to White men (37%). Age was inversely associated with likelihood of receiving RP. Having private insurance was significantly associated with the increased use of RP (vs Medicare, adjusted odds ratio 1.04, 95% CI 1.01-1.08, P=0.015). Biopsy Gleason scores 8-10 with and without any primary Gleason 5 pattern were associated with decreased odds of RP (vs Gleason score ⩽6, both P<0.001). Academic and comprehensive cancer centers were more likely to perform RP compared to community hospitals (both P<0.001). The likelihood of receiving RP for high-risk PCa dramatically increased from 2004 to 2013. By 2013, the use of RP and EBRT were similar. African American men, elderly men and those without private insurance were less likely to receive RP.

Impaired global, and compensatory local, biological motion processing in people with high levels of autistic traits.

Science.gov (United States)

van Boxtel, Jeroen J A; Lu, Hongjing

2013-01-01

People with Autism Spectrum Disorder (ASD) are hypothesized to have poor high-level processing but superior low-level processing, causing impaired social recognition, and a focus on non-social stimulus contingencies. Biological motion perception provides an ideal domain to investigate exactly how ASD modulates the interaction between low and high-level processing, because it involves multiple processing stages, and carries many important social cues. We investigated individual differences among typically developing observers in biological motion processing, and whether such individual differences associate with the number of autistic traits. In Experiment 1, we found that individuals with fewer autistic traits were automatically and involuntarily attracted to global biological motion information, whereas individuals with more autistic traits did not show this pre-attentional distraction. We employed an action adaptation paradigm in the second study to show that individuals with more autistic traits were able to compensate for deficits in global processing with an increased involvement in local processing. Our findings can be interpreted within a predictive coding framework, which characterizes the functional relationship between local and global processing stages, and explains how these stages contribute to the perceptual difficulties associated with ASD.

Impaired global, and compensatory local, biological motion processing in people with high levels of autistic traits

Directory of Open Access Journals (Sweden)

Jeroen J A Van Boxtel

2013-04-01

Full Text Available People with Autism Spectrum Disorder (ASD are hypothesized to have poor high-level processing but superior low-level processing, causing impaired social recognition, and a focus on non-social stimulus contingencies. Biological motion perception provides an ideal domain to investigate exactly how ASD modulates the interaction between low and high-level processing, because it involves multiple processing stages, and carries many important social cues. We investigated individual differences among typically developing observers in biological motion processing, and whether such individual differences associate with the number of autistic traits. In Experiment 1, we found that individuals with fewer autistic traits were automatically and involuntarily attracted to global biological motion information, whereas individuals with more autistic traits did not show this pre-attentional distraction. We employed an action adaptation paradigm in the second study to show that individuals with more autistic traits were able to compensate for deficits in global processing with an increased involvement in local processing. Our findings can be interpreted within a predictive coding framework, which characterizes the functional relationship between local and global processing stages, and explains how these stages contribute to the perceptual difficulties associated with ASD.

A high resolution interferometric method to measure local swelling due to CO2 exposure in coal and shale

NARCIS (Netherlands)

Pluymakers, A.; Liu, J.; Kohler, F.; Renard, F.; Dysthe, D.

2018-01-01

We present an experimental method to study time-dependent, CO2-induced, local topography changes in mm-sized composite samples, plus results showing heterogeneous swelling of coal and shale on the nano- to micrometer scale. These results were obtained using high resolution interferometry

Experiences from two local processes of debate and referenda on the issue of siting high level nuclear waste

International Nuclear Information System (INIS)

Drottz Sjoberg, B.M.

1998-01-01

Full text of publication follows: the paper summarizes results from two interview studies conducted in the communities of Storuman (1995) and Malaa (1997) in northern Sweden regarding whether to continue investigations of the areas for siting of a deep level repository for high level nuclear waste. Active, local participants in the work and discussions preceding each local referendum on the issue were asked to reflect on reasons and considerations related to their opinions, as well as the overall outcome for achieving a deeper understanding of the local processes. The first referendum (1995) yielded a strongly voiced rejection of continuing local investigations (72%), whereas the second (1997) referendum resulted in a marginally negative response (54%). A comparison of the results of the interview studies showed e.g. that the decision processes differed across communities, regarding both time interval and content, and that the local strategies and tactics related to the campaigns preceding the referenda differed. Among the similarities were the types of questions which remained unclear, often related to a long term perspective, e.g. risks and uncertainties regarding material reliability, access to and future safety of the repository, concern for future generations, national and international long-term decision procedures, and roles of responsibility. The discussion focuses on considerations around the issue of local vs. centralized political decisions and the tool provided by the referendum, and touches upon some issues which appeared rather paradoxical. (author)

Diversity And Abundance Of Deep-Water Coral Mounds In The Straits Of Florida: A Result of Adaptability To Local Environments?

Science.gov (United States)

Correa, T. B.; Grasmueck, M.; Eberli, G.; Viggiano, D. A.; Rosenberg, A.; Reed, J. K.

2007-12-01

To improve the understanding of the Florida-Bahamas deep-water coral mound ecosystem, Autonomous Underwater Vehicle (AUV) surveys were conducted on five coral mound fields throughout the Straits of Florida (three sites at the base of slope of Great Bahama Bank (GBB), one in the middle of the Straits (MS) and one at the base of the Miami Terrace (MT)) in water depths of 590 to 860 m. The AUV provides high-resolution bathymetric maps, sub-bottom profiles and oceanographic data. The AUV survey sites were subsequently groundtruthed via sample collection and video transects, using the Johnson Sealink submersible. Contrary to previous surveys, we found a high diversity in coral mound morphology between sites separated by 15 to 80 km. The MT site is characterized by sinusoidal coral mound ridges, while the MS site contains densely clustered small coral mounds. Meanwhile, mounds of the GBB region are better developed, with some individual mounds reaching up to 90 m in height. Benthic coverage of live corals also differs between sites; the GBB sites are characterized by mounds densely covered by large thickets of live corals, while small thickets of mostly dead corals dominate the MT and MS sites. Several environmental factors may explain these differences. For example, bottom current patterns change between sites. The MT and the MS sites have a unidirectional regime (southward or northward flow, respectively), whereas the GBB sites have a tidal current regime. Sedimentation patterns as depicted by sub-bottom profiles also vary between the sites; coral mounds in the GBB area appear to receive higher sediment input, which can significantly enhance mound growth rates as the reef framework baffles and traps mobile sediments. However, coral mounds that cannot keep-up with the sedimentation rate are buried. Therefore, in the high sedimentation areas of GBB, flourishing live coral mounds are limited to elevated positions (i.e. plateaus, ridges crests) where sediment accumulation

What is the optimal management of high risk, clinically localized prostate cancer?

Science.gov (United States)

Eastham, James A; Evans, Christopher P; Zietman, Anthony

2010-01-01

To summarize the presentations and debate regarding the optimal treatment of localized high-risk prostate cancer as presented at the 2009 Spring Meeting of the Society of Urologic Oncology. The debate was centered on presentations arguing for radical prostatectomy (RP) or radiotherapy as the optimal treatment for this condition. The meeting presentations are summarized by their respective presenters herein. Dr. James Eastham presents the varied definitions for "high-risk" prostate cancer as strongly influencing which patients end up in this cohort. Based upon this, between 3% and 38% of patients with high-risk features could be defined as "high-risk". Despite that, these men do not have a uniformly poor prognosis after RP, and attention to surgical principles as outlined improve outcomes. Disease-specific survival at 12 years is excellent and up to one-half of these men may not need adjuvant or salvage therapies, depending on their specific disease characteristics. Adjuvant or salvage radiotherapies improve outcomes and are part of a sequential approach to treating these patients. Dr. Anthony Zietman presented radiotherapy as the gold-standard based upon large, randomized clinical trials of intermediate- and high-risk prostate cancer patients. Compared with androgen deprivation alone, the addition of radiotherapy provided a 12% cancer-specific survival advantage and 10% overall survival advantage. Dose escalation seems to confer further improvements in cancer control without significant escalation of toxicities, with more data forthcoming. There are no randomized trials comparing RP to radiotherapy for any risk category. In high-risk prostate cancer patients, both approaches have potential benefits and cumulative toxicities that must be matched to disease characteristics and patient expectations in selecting a treatment course. Copyright (c) 2010 Elsevier Inc. All rights reserved.

The origin of local strain in highly epitaxial oxide thin films.

Science.gov (United States)

Ma, Chunrui; Liu, Ming; Chen, Chonglin; Lin, Yuan; Li, Yanrong; Horwitz, J S; Jiang, Jiechao; Meletis, E I; Zhang, Qingyu

2013-10-31

The ability to control the microstructures and physical properties of hetero-epitaxial functional oxide thin films and artificial structures is a long-sought goal in functional materials research. Normally, only the lattice misfit between the film and the substrate is considered to govern the physical properties of the epitaxial films. In fact, the mismatch of film unit cell arrangement and the Surface-Step-Terrace (SST) dimension of the substrate, named as "SST residual matching", is another key factor that significantly influence the properties of the epitaxial film. The nature of strong local strain induced from both lattice mismatch and the SST residual matching on ferroelectric (Ba,Sr)TiO3 and ferromagnetic (La,Ca)MnO3 thin films are systematically investigated and it is demonstrated that this combined effect has a dramatic impact on the physical properties of highly epitaxial oxide thin films. A giant anomalous magnetoresistance effect (~10(10)) was achieved from the as-designed vicinal surfaces.

Newmark local time stepping on high-performance computing architectures

KAUST Repository

Rietmann, Max

2016-11-25

In multi-scale complex media, finite element meshes often require areas of local refinement, creating small elements that can dramatically reduce the global time-step for wave-propagation problems due to the CFL condition. Local time stepping (LTS) algorithms allow an explicit time-stepping scheme to adapt the time-step to the element size, allowing near-optimal time-steps everywhere in the mesh. We develop an efficient multilevel LTS-Newmark scheme and implement it in a widely used continuous finite element seismic wave-propagation package. In particular, we extend the standard LTS formulation with adaptations to continuous finite element methods that can be implemented very efficiently with very strong element-size contrasts (more than 100×). Capable of running on large CPU and GPU clusters, we present both synthetic validation examples and large scale, realistic application examples to demonstrate the performance and applicability of the method and implementation on thousands of CPU cores and hundreds of GPUs.

Newmark local time stepping on high-performance computing architectures

KAUST Repository

Rietmann, Max; Grote, Marcus; Peter, Daniel; Schenk, Olaf

2016-01-01

In multi-scale complex media, finite element meshes often require areas of local refinement, creating small elements that can dramatically reduce the global time-step for wave-propagation problems due to the CFL condition. Local time stepping (LTS) algorithms allow an explicit time-stepping scheme to adapt the time-step to the element size, allowing near-optimal time-steps everywhere in the mesh. We develop an efficient multilevel LTS-Newmark scheme and implement it in a widely used continuous finite element seismic wave-propagation package. In particular, we extend the standard LTS formulation with adaptations to continuous finite element methods that can be implemented very efficiently with very strong element-size contrasts (more than 100×). Capable of running on large CPU and GPU clusters, we present both synthetic validation examples and large scale, realistic application examples to demonstrate the performance and applicability of the method and implementation on thousands of CPU cores and hundreds of GPUs.

Newmark local time stepping on high-performance computing architectures

Energy Technology Data Exchange (ETDEWEB)

Rietmann, Max, E-mail: max.rietmann@erdw.ethz.ch [Institute for Computational Science, Università della Svizzera italiana, Lugano (Switzerland); Institute of Geophysics, ETH Zurich (Switzerland); Grote, Marcus, E-mail: marcus.grote@unibas.ch [Department of Mathematics and Computer Science, University of Basel (Switzerland); Peter, Daniel, E-mail: daniel.peter@kaust.edu.sa [Institute for Computational Science, Università della Svizzera italiana, Lugano (Switzerland); Institute of Geophysics, ETH Zurich (Switzerland); Schenk, Olaf, E-mail: olaf.schenk@usi.ch [Institute for Computational Science, Università della Svizzera italiana, Lugano (Switzerland)

2017-04-01

In multi-scale complex media, finite element meshes often require areas of local refinement, creating small elements that can dramatically reduce the global time-step for wave-propagation problems due to the CFL condition. Local time stepping (LTS) algorithms allow an explicit time-stepping scheme to adapt the time-step to the element size, allowing near-optimal time-steps everywhere in the mesh. We develop an efficient multilevel LTS-Newmark scheme and implement it in a widely used continuous finite element seismic wave-propagation package. In particular, we extend the standard LTS formulation with adaptations to continuous finite element methods that can be implemented very efficiently with very strong element-size contrasts (more than 100x). Capable of running on large CPU and GPU clusters, we present both synthetic validation examples and large scale, realistic application examples to demonstrate the performance and applicability of the method and implementation on thousands of CPU cores and hundreds of GPUs.

The Early Result of Whole Pelvic Radiotherapy and Stereotactic Body Radiotherapy Boost for High Risk Localized Prostate Cancer

Directory of Open Access Journals (Sweden)

Yu-Wei eLin

2014-10-01

Full Text Available PurposeThe rationale for hypofractionated radiotherapy in the treatment of prostate cancer is based on the modern understanding of radiobiology and advances in stereotactic body radiotherapy (SBRT techniques. Whole-pelvis irradiation combined with SBRT boost for high-risk prostate cancer might escalate biologically effective dose without increasing toxicity. Here, we report our 4-year results of SBRT boost for high-risk localized prostate cancer.Methods and MaterialsFrom October 2009 to August 2012, 41 patients of newly diagnosed, high-risk or very high-risk (NCCN definition localized prostate cancer patients were treated with whole-pelvis irradiation and SBRT boost. The whole pelvis dose was 45Gy (25 fractions of 1.8Gy. The SBRT boost dose was 21 Gy (three fractions of 7 Gy. Ninety percent of these patients received hormone therapy. The toxicities of gastrointestinal (GI and genitourinary (GU tracts were scored by Common Toxicity Criteria Adverse Effect (CTCAE v3.0. Biochemical failure was defined by Phoenix definition.ResultsMedian follow-up was 42 months. Mean PSA before treatment was 44.18 ng/ml. Mean PSA level at 3, 6, 12, 18, and 24 months was 0.94, 0.44, 0.13, 0.12, and 0.05 ng/ml, respectively. The estimated 4-year biochemical failure-free survival was 91.9%. Three biochemical failures were observed. GI and GU tract toxicities were minimal. No grade 3 acute GU or GI toxicity was noted. During radiation therapy, 27% of the patient had grade 2 acute GU toxicity and 12% had grade 2 acute GI toxicity. At 3 months, most toxicity scores had returned to baseline. At the last follow up, there was no grade 3 late GU or GI toxicity.ConclusionsWhole-pelvis irradiation combined with SBRT boost for high-risk localized prostate cancer is feasible with minimal toxicity and encouraging biochemical failure-free survival. Continued accrual and follow-up would be necessary to confirm the biochemical control rate and the toxicity profiles.

Localization effects in rare earth high Tc superconductors

International Nuclear Information System (INIS)

Badera, Nitu; Godbole, Bhavana; Srivastava, S.B.; Rathore, M.K.; Ganesa, V.

2006-01-01

The Y 1-x Gd x Ba 2 Cu 3 O 7-δ samples have been prepared for different concentration of Gd . We employ thermoelectric power technique, which is sensitive to changes at the Fermi surface to study these materials. Metallic diffusion model and two band model are used to evaluate the normal state properties of these materials. At concentrations above 5% clear wide linear regions have been observed suggesting good evidence for localized states. (author)

Understanding Local Policy Elites' Perceptions on the Benefits and Risks Associated with High-Voltage Power Line Installations in the State of Arkansas.

Science.gov (United States)

Moyer, Rachael M; Song, Geoboo

2016-10-01

Recently, a controversial policy debate has arisen concerning the installation of high-voltage power lines in northwest Arkansas. While proponents argue that such an installation is inevitable to efficiently and reliably support the identified electric load in the region, opponents claim that the lines will degrade the natural environment and hamper the tourism-based local economy in affected regions, notably in Ozark Mountain areas. Of particular interest is to understand how local policy elites perceive the benefits and risks associated with such divisive proposals, which is critical for comprehending the formation and changes of related government policies. Based upon the dual process theory of judgment, this study systematically investigates the triadic relationships between (a) more profound personal value predispositions, (b) affects and feelings, and (c) perceived benefits and risks related to the proposed installation of high-voltage power lines among local policy elites in the state of Arkansas. In doing so, we analyze original data collected from a statewide Internet survey of 420 local leaders and key policymakers about their opinions on the related issues, while considering other factors claimed by previous literature to influence risk perceptions, including trust, knowledge level, and demographic characteristics. Analytical results suggest that grid-group cultural predispositions, as deeply held core values within local policy elites' individual belief systems, both directly and indirectly-through affective feelings-shape perceived utility associated with the installation of high-voltage power lines. We conclude this article by suggesting some practical considerations for better designing policy addressing controversial issues of this nature. © 2016 Society for Risk Analysis.

The Recidivism Patterns of Previously Deported Aliens Released from a Local Jail: Are They High-Risk Offenders?

Science.gov (United States)

Hickman, Laura J.; Suttorp, Marika J.

2010-01-01

Previously deported aliens are a group about which numerous claims are made but very few facts are known. Using data on male deportable aliens released from a local jail, the study sought to test the ubiquitous claim that they pose a high risk of recidivism. Using multiple measures of recidivism and propensity score weighting to account for…

Computational modeling of river flow using bathymetry collected with an experimental, water-penetrating, green LiDAR

Science.gov (United States)

Kinzel, P. J.; Legleiter, C. J.; Nelson, J. M.

2009-12-01

Airborne bathymetric Light Detection and Ranging (LiDAR) systems designed for coastal and marine surveys are increasingly being deployed in fluvial environments. While the adaptation of this technology to rivers and streams would appear to be straightforward, currently technical challenges remain with regard to achieving high levels of vertical accuracy and precision when mapping bathymetry in shallow fluvial settings. Collectively these mapping errors have a direct bearing on hydraulic model predictions made using these data. We compared channel surveys conducted along the Platte River, Nebraska, and the Trinity River, California, using conventional ground-based methods with those made with the hybrid topographic/bathymetric Experimental Advanced Airborne Research LiDAR (EAARL). In the turbid and braided Platte River, a bathymetric-waveform processing algorithm was shown to enhance the definition of thalweg channels over a more simplified, first-surface waveform processing algorithm. Consequently flow simulations using data processed with the shallow bathymetric algorithm resulted in improved prediction of wetted area relative to the first-surface algorithm, when compared to the wetted area in concurrent aerial imagery. However, when compared to using conventionally collected data for flow modeling, the inundation extent was over predicted with the EAARL topography due to higher bed elevations measured by the LiDAR. In the relatively clear, meandering Trinity River, bathymetric processing algorithms were capable of defining a 3 meter deep pool. However, a similar bias in depth measurement was observed, with the LiDAR measuring the elevation of the river bottom above its actual position, resulting in a predicted water surface higher than that measured by field data. This contribution addresses the challenge of making bathymetric measurements with the EAARL in different environmental conditions encountered in fluvial settings, explores technical issues related to

High-dose-rate brachytherapy as salvage modality for locally recurrent prostate cancer after definitive radiotherapy. A systematic review

International Nuclear Information System (INIS)

Chatzikonstantinou, Georgios; Zamboglou, Nikolaos; Roedel, Claus; Tselis, Nikolaos; Zoga, Eleni; Strouthos, Iosif; Butt, Saeed Ahmed

2017-01-01

To review the current status of interstitial high-dose-rate brachytherapy as a salvage modality (sHDR BRT) for locally recurrent prostate cancer after definitive radiotherapy (RT). A literature search was performed in PubMed using ''high-dose-rate, brachytherapy, prostate cancer, salvage'' as search terms. In all, 51 search results published between 2000 and 2016 were identified. Data tables were generated and summary descriptions created. The main outcome parameters used were biochemical control (BC) and toxicity scores. Eleven publications reported clinical outcome and toxicity with follow-up ranging from 4-191 months. A variety of dose and fractionation schedules were described, including 19.0 Gy in 2 fractions up to 42.0 Gy in 6 fractions. The 5-year BC ranged from 18-77%. Late grade 3 genitourinary and gastrointestinal toxicity was 0-32% and 0-5.1%, respectively. sHDR BRT appears as safe and effective salvage modality for the reirradiation of locally recurrent prostate cancer after definitive RT. (orig.) [de

High-precision two-dimensional atom localization from four-wave mixing in a double-Λ four-level atomic system

Science.gov (United States)

Shui, Tao; Yang, Wen-Xing; Chen, Ai-Xi; Liu, Shaopeng; Li, Ling; Zhu, Zhonghu

2018-03-01

We propose a scheme for high-precision two-dimensional (2D) atom localization via the four-wave mixing (FWM) in a four-level double-Λ atomic system. Due to the position-dependent atom-field interaction, the 2D position information of the atoms can be directly determined by the measurement of the normalized light intensity of output FWM-generated field. We further show that, when the position-dependent generated FWM field has become sufficiently intense, efficient back-coupling to the FWM generating state becomes important. This back-coupling pathway leads to competitive multiphoton destructive interference of the FWM generating state by three supplied and one internally generated fields. We find that the precision of 2D atom localization can be improved significantly by the multiphoton destructive interference and depends sensitively on the frequency detunings and the pump field intensity. Interestingly enough, we show that adjusting the frequency detunings and the pump field intensity can modify significantly the FWM efficiency, and consequently lead to a redistribution of the atoms. As a result, the atom can be localized in one of four quadrants with holding the precision of atom localization.

Focus on Local Reaction.

Science.gov (United States)

Howe, Rod

1999-01-01

Discusses how the student newspaper "The Lance" (at Westside High School in Omaha, Nebraska) covered the shootings at Columbine High School. Notes that the staff localized the event and brought the student body into the story. (RS)

A tailing genome walking method suitable for genomes with high local GC content.

Science.gov (United States)

Liu, Taian; Fang, Yongxiang; Yao, Wenjuan; Guan, Qisai; Bai, Gang; Jing, Zhizhong

2013-10-15

The tailing genome walking strategies are simple and efficient. However, they sometimes can be restricted due to the low stringency of homo-oligomeric primers. Here we modified their conventional tailing step by adding polythymidine and polyguanine to the target single-stranded DNA (ssDNA). The tailed ssDNA was then amplified exponentially with a specific primer in the known region and a primer comprising 5' polycytosine and 3' polyadenosine. The successful application of this novel method for identifying integration sites mediated by φC31 integrase in goat genome indicates that the method is more suitable for genomes with high complexity and local GC content. Copyright © 2013 Elsevier Inc. All rights reserved.

Statistical significance approximation in local trend analysis of high-throughput time-series data using the theory of Markov chains.

Science.gov (United States)

Xia, Li C; Ai, Dongmei; Cram, Jacob A; Liang, Xiaoyi; Fuhrman, Jed A; Sun, Fengzhu

2015-09-21

Local trend (i.e. shape) analysis of time series data reveals co-changing patterns in dynamics of biological systems. However, slow permutation procedures to evaluate the statistical significance of local trend scores have limited its applications to high-throughput time series data analysis, e.g., data from the next generation sequencing technology based studies. By extending the theories for the tail probability of the range of sum of Markovian random variables, we propose formulae for approximating the statistical significance of local trend scores. Using simulations and real data, we show that the approximate p-value is close to that obtained using a large number of permutations (starting at time points >20 with no delay and >30 with delay of at most three time steps) in that the non-zero decimals of the p-values obtained by the approximation and the permutations are mostly the same when the approximate p-value is less than 0.05. In addition, the approximate p-value is slightly larger than that based on permutations making hypothesis testing based on the approximate p-value conservative. The approximation enables efficient calculation of p-values for pairwise local trend analysis, making large scale all-versus-all comparisons possible. We also propose a hybrid approach by integrating the approximation and permutations to obtain accurate p-values for significantly associated pairs. We further demonstrate its use with the analysis of the Polymouth Marine Laboratory (PML) microbial community time series from high-throughput sequencing data and found interesting organism co-occurrence dynamic patterns. The software tool is integrated into the eLSA software package that now provides accelerated local trend and similarity analysis pipelines for time series data. The package is freely available from the eLSA website: http://bitbucket.org/charade/elsa.

Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells

Science.gov (United States)

Nguyen, Minh M.; Dar, Javid A.; Ai, Junkui; Wang, Yujuan; Masoodi, Khalid Z.; Shun, Tongying; Shinde, Sunita; Camarco, Daniel P.; Hua, Yun; Huryn, Donna M.; Wilson, Gabriela Mustata; Lazo, John S.; Nelson, Joel B.; Wipf, Peter

2016-01-01

Abstract Patients with castration-resistant prostate cancer (CRPC) can be treated with abiraterone, a potent inhibitor of androgen synthesis, or enzalutamide, a second-generation androgen receptor (AR) antagonist, both targeting AR signaling. However, most patients relapse after several months of therapy and a majority of patients with relapsed CRPC tumors express the AR target gene prostate-specific antigen (PSA), suggesting that AR signaling is reactivated and can be targeted again to inhibit the relapsed tumors. Novel small molecules capable of inhibiting AR function may lead to urgently needed therapies for patients resistant to abiraterone, enzalutamide, and/or other previously approved antiandrogen therapies. Here, we describe a high-throughput high-content screening (HCS) campaign to identify small-molecule inhibitors of AR nuclear localization in the C4-2 CRPC cell line stably transfected with GFP-AR-GFP (2GFP-AR). The implementation of this HCS assay to screen a National Institutes of Health library of 219,055 compounds led to the discovery of 3 small molecules capable of inhibiting AR nuclear localization and function in C4-2 cells, demonstrating the feasibility of using this cell-based phenotypic assay to identify small molecules targeting the subcellular localization of AR. Furthermore, the three hit compounds provide opportunities to develop novel AR drugs with potential for therapeutic intervention in CRPC patients who have relapsed after treatment with antiandrogens, such as abiraterone and/or enzalutamide. PMID:27187604

Long Island Sound Environmental Studies; 01 October 1991 to 31 August 1998 (NODC Accession 9900223)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Abstract: This CD-ROM (Compact Disk - Read Only Memory) contains sidescan sonar, high-resolution seismic-reflection, bathymetric, textural, and bibliographic data...

Selective tuning of high-Q silicon photonic crystal nanocavities via laser-assisted local oxidation.

Science.gov (United States)

Chen, Charlton J; Zheng, Jiangjun; Gu, Tingyi; McMillan, James F; Yu, Mingbin; Lo, Guo-Qiang; Kwong, Dim-Lee; Wong, Chee Wei

2011-06-20

We examine the cavity resonance tuning of high-Q silicon photonic crystal heterostructures by localized laser-assisted thermal oxidation using a 532 nm continuous wave laser focused to a 2.5 μm radius spot-size. The total shift is consistent with the parabolic rate law. A tuning range of up to 8.7 nm is achieved with ∼ 30 mW laser powers. Over this tuning range, the cavity Qs decreases from 3.2×10(5) to 1.2×10(5). Numerical simulations model the temperature distributions in the silicon photonic crystal membrane and the cavity resonance shift from oxidation.

Robust non-local median filter

Science.gov (United States)

Matsuoka, Jyohei; Koga, Takanori; Suetake, Noriaki; Uchino, Eiji

2017-04-01

This paper describes a novel image filter with superior performance on detail-preserving removal of random-valued impulse noise superimposed on natural gray-scale images. The non-local means filter is in the limelight as a way of Gaussian noise removal with superior performance on detail preservation. By referring the fundamental concept of the non-local means, we had proposed a non-local median filter as a specialized way for random-valued impulse noise removal so far. In the non-local processing, the output of a filter is calculated from pixels in blocks which are similar to the block centered at a pixel of interest. As a result, aggressive noise removal is conducted without destroying the detailed structures in an original image. However, the performance of non-local processing decreases enormously in the case of high noise occurrence probability. A cause of this problem is that the superimposed noise disturbs accurate calculation of the similarity between the blocks. To cope with this problem, we propose an improved non-local median filter which is robust to the high level of corruption by introducing a new similarity measure considering possibility of being the original signal. The effectiveness and validity of the proposed method are verified in a series of experiments using natural gray-scale images.

Economic Learning Media Development Based on Local Locality

Science.gov (United States)

Hadi, Rizali; Supriyanto; Hasanah, Mahmudah

2017-01-01

This study aims to describe the learning medium of economic education at senior High School in Banjarmasin with media based on local wisdom. This research uses qualitative method as developed by Miles & Huberman, starting from data collection, data reduction data display, and then made conclusion. Data were collected in the order of Basic…

Non-solenoidal Startup with High-Field-Side Local Helicity Injection on the Pegasus ST

Science.gov (United States)

Perry, J. M.; Bodner, G. M.; Bongard, M. W.; Burke, M. G.; Fonck, R. J.; Pachicano, J. L.; Pierren, C.; Richner, N. J.; Rodriguez Sanchez, C.; Schlossberg, D. J.; Reusch, J. A.; Weberski, J. D.

2017-10-01

Local Helicity Injection (LHI) is a non-solenoidal startup technique utilizing electron current injectors at the plasma edge to initiate a tokamak-like plasma at high Ip . Recent experiments on Pegasus explore the inherent tradeoffs between high-field-side (HFS) injection in the lower divertor region and low-field-side (LFS) injection at the outboard midplane. Trade-offs include the relative current drive contributions of HI and poloidal induction, and the magnetic geometry required for relaxation to a tokamak-like state. HFS injection using a set of two increased-area injectors (Ainj = 4 cm2, Vinj 1.5 kV, and Iinj 8 kA) in the lower divertor is demonstrated over the full range of toroidal field available on Pegasus (BT 0 = 10) attainable with LHI and the favorable stability of the ultra-low aspect ratio, low-li LHI-driven plasmas allow access to high βt-up to 100 % , as indicated by kinetically-constrained equilibrium reconstructions. Work supported by US DOE Grant DE-FG02-96ER54375.

High levels of xanthine oxidoreductase in rat endothelial, epithelial and connective tissue cells. A relation between localization and function?

NARCIS (Netherlands)

Kooij, A.; Bosch, K. S.; Frederiks, W. M.; van Noorden, C. J.

1992-01-01

The localization of xanthine oxidoreductase activity was investigated in unfixed cryostat sections of various rat tissues by an enzyme histochemical method which specifically demonstrates both the dehydrogenase and oxidase forms of xanthine oxidoreductase. High activity was found in epithelial cells

Study of the weak localization in high quality two dimensional p-GaAs/AIGaAs systems

International Nuclear Information System (INIS)

Yasin, C.E.; Simmons, M.Y.; Hamilton, A.R.; Pepper, M.; Ritchie, D.A.

2002-01-01

Full text: Despite numerous experimental and theoretical work over the past ∼ 30 years, the nature of the ground state in 2D semiconductor systems remains a subject of controversy. Does the anomalous 'metallic' behavior observed at B = 0 imply the existence of a new 2D 'metallic' ground state or can it be explained within the conventional Fermi liquid theory? To address this question, we have investigated the single particle phase coherent 'weak localization' effect in high quality 2D p-GaAs systems that shows an apparent ' metallic' behavior at B = 0. We have performed detailed temperature dependent magnetoresistance measurements at different carrier densities and fit the experimental data to various models of weak localization in order to extract the phase coherence time, τ φ . We find that as the sample quality increases the mean free path increases, and weak localization must be treated beyond the diffusion approximation, making the data analysis more complex. Our result shows that when these more complex models are applied to the experimental data the systems are well described by Fermi liquid theory despite the strong interactions (r s ∼ 20), indicating that there is no 'metallic' phase in 2D at B = 0

100% of the World Ocean Floor Mapped by 2030 - Contribution of the South and West Pacific Regional Data Assembly and Coordination Centre to the Seabed 2030 Initiative

Science.gov (United States)

Lamarche, G.; Neil, H.; Stagpoole, V. M.; Greenland, A.; Mackay, K.; Black, J.; Griffin, E.

2017-12-01

The Seabed 2030 SaWPac Centre (South and West Pacific Ocean Regional Data Assembly and Coordination Centre) has been formed to generate new high resolution ocean floor maps of the western and southern Pacific Ocean. The centre is part of the joint Nippon Foundation and the General Bathymetric Chart of the Oceans (GEBCO) initiative to produce a definitive map of the World Ocean floor by 2030, empowering the world to make policy decisions, use the ocean sustainability and undertake scientific research based on detailed bathymetric information of the Earth's seabed. The SaWPac Centre is based at NIWA Wellington (New Zealand) and includes a collaborative partnership with GNS Science and Land Information New Zealand. It is responsible for the region from South America to Australia, north of latitude 50°S to 10° north of the Equator and the western part of the Northern Pacific Ocean to Russia. The region includes the world's deepest trenches and also covers some of the remotest oceans where bathymetric data form existing ship tracks is spaced up to 100 km apart. The challenge for the SaWPac Centre is to collate and combine all the available bathymetric data from the numerous nations that have surveyed in the region. The centre will also promote efforts to collect new data and contribute to map products generated by the Seabed 2030 global mapping project.

High-Resolution, Long-Slit Spectroscopy of VY Canis Majoris: The Evidence for Localized High Mass Loss Events

Science.gov (United States)

Humphreys, Roberta M.; Davidson, Kris; Ruch, Gerald; Wallerstein, George

2005-01-01

High spatial and spectral resolution spectroscopy of the OH/IR supergiant VY CMa and its circumstellar ejecta reveals evidence for high mass loss events from localized regions on the star occurring over the past 1000 yr. The reflected absorption lines and the extremely strong K I emission lines show a complex pattern of velocities in the ejecta. We show that the large, dusty northwest arc, expanding at ~50 km s-1 with respect to the embedded star, is kinematically distinct from the surrounding nebulosity and was ejected about 400 yr ago. Other large, more filamentary loops were probably expelled as much as 800-1000 yr ago, whereas knots and small arcs close to the star resulted from more recent events 100-200 yr ago. The more diffuse, uniformly distributed gas and dust is surprisingly stationary, with little or no velocity relative to the star. This is not what we would expect for the circumstellar material from an evolved red supergiant with a long history of mass loss. We therefore suggest that the high mass loss rate for VY CMa is a measure of the mass carried out by these specific ejections accompanied by streams or flows of gas through low-density regions in the dust envelope. VY CMa may thus be our most extreme example of stellar activity, but our results also bring into question the evolutionary state of this famous star. In a separate appendix, we discuss the origin of the very strong K I and other rare emission lines in its spectrum.

Adaptive beamforming for low frequency SAS imagery and bathymetry

NARCIS (Netherlands)

Hayes, M.P.; Hunter, A.J.

2012-01-01

Synthetic aperture side-scan sonar (SAS) is a mature technology for high-resolution sea floor imaging [1]. Interferometric synthetic aperture sonars (InSAS) use additional hydrophones in a vertical array for bathymetric mapping [2]. This has created high-resolution bathymetry in deep water

Hitting times of local and global optima in genetic algorithms with very high selection pressure

Directory of Open Access Journals (Sweden)

Eremeev Anton V.

2017-01-01

Full Text Available The paper is devoted to upper bounds on the expected first hitting times of the sets of local or global optima for non-elitist genetic algorithms with very high selection pressure. The results of this paper extend the range of situations where the upper bounds on the expected runtime are known for genetic algorithms and apply, in particular, to the Canonical Genetic Algorithm. The obtained bounds do not require the probability of fitness-decreasing mutation to be bounded by a constant which is less than one.

Definitive intraoperative very high-dose radiotherapy for localized osteosarcoma in the extremities

International Nuclear Information System (INIS)

Oya, Natsuo; Kokubo, Masaki; Mizowaki, Takashi; Shibamoto, Yuta; Nagata, Yasushi; Sasai, Keisuke; Nishimura, Yasumasa; Tsuboyama, Tadao; Toguchida, Junya; Nakamura, Takashi; Hiraoka, Masahiro

2001-01-01

Purpose: To evaluate the outcome and adverse effects in patients with osteosarcoma treated with very high-dose definitive intraoperative radiotherapy (IORT), with the intention of saving the affected limb. Methods and Materials: Thirty-nine patients with osteosarcoma in their extremities were treated with definitive IORT. The irradiation field included the tumor plus an adequate wide margin and excluded the major vessels and nerves. Forty-five to 80 Gy of electrons or X-rays were delivered. The median follow-up of the surviving patients was 124 months. Results: The cause-specific and relapse-free 5-year survival rate was 50% and 43%, respectively. Distant metastasis developed in 23 patients; 19 died and 4 were alive for >10 years. Nine local recurrences were found 4-29 months after IORT in the affected limb. No radiation-induced skin reaction or nerve palsy was observed in the patients treated with X-rays. Experiments using phantoms also confirmed that the scatter dose was below the toxic level in the IORT setting with X-rays. Conclusions: Very high-dose definitive IORT combined with preventive nailing and chemotherapy appeared to be a promising quality-of-life-oriented alternative to treating patients with osteosarcomas in the extremities, although the problem of recurrences from the surrounding unirradiated soft tissue remains to be solved

Multibeam bathymetric survey of the Ipala Submarine Canyon, Jalisco, Mexico (20°N): The southern boundary of the Banderas Forearc Block?

Science.gov (United States)

Urías Espinosa, J.; Bandy, W. L.; Mortera Gutiérrez, C. A.; Núñez Cornú, Fco. J.; Mitchell, N. C.

2016-03-01

The Middle America Trench bends sharply northward at 20°N. This, along with the close proximity of the Rivera-North America Euler pole to the northern end of this trench, sharply increases the obliquity of subduction at 20°N. By analogy with other subduction zones with similar sharply changing obliquity, significant trench parallel extension is expected to exist in the forearc region near the bend. To evaluate this possibility, multibeam bathymetric, seafloor backscatter and sub-bottom seismic reflection data were collected in this area during the MORTIC08 campaign of the B.O. El Puma. These data image in detail a large submarine canyon (the Ipala Canyon) extending from the coast at 20°05‧N to the Middle America Trench at 19°50‧N. This canyon is 114 km long and is fed by sediments originating from two, possibly three, small rivers: the Ipala, Tecolotlán and Maria Garza. This canyon deeply incises (up to 600 m) the entire continental slope and at least the outer part of the shelf. Within the canyon, we observe meanders and narrow channels produced by turbidity flows indicating that the canyon is active. In the marginal areas of the canyon slumps, rills, and uplifts suggest that mass movements and fluid flow have had a major impact on the seafloor morphology. The seafloor bathymetry, backscatter images and sub-bottom reflection profiles evidence the tectonic processes occurring in this area. Of particular interest, the canyon is deflected by almost 90° at three locations, the deflections all having a similar azimuth of between 125° and 130°. Given the prominence and geometry of this canyon, along with its tectonic setting, we propose that the presence of the canyon is related to extension produced by the sharp change in the plate convergence. If so, the canyon may lie along the southeast boundary of a major forearc block (the Banderas Forearc Block).

What Will Science Gain From Mapping the World Ocean Floor?

Science.gov (United States)

Jakobsson, M.

2017-12-01

It is difficult to estimate how much of the World Ocean floor topography (bathymetry) that has been mapped. Estimates range from a few to more than ten percent of the World Ocean area. The most recent version of the bathymetric grid compiled by the General Bathymetric Chart of the Oceans (GEBCO) has bathymetric control points in 18% of the 30 x 30 arc second large grid cells. The depth values for the rest of the cells are obtained through interpolation guided by satellite altimetry in deep water. With this statistic at hand, it seems tenable to suggest that there are many scientific discoveries to be made from a complete high-resolution mapping of the World Ocean floor. In this presentation, some of our recent scientific discoveries based on modern multibeam bathymetric mapping will be highlighted and discussed. For example, how multibeam mapping provided evidence for a km-thick ice shelf covering the entire Arctic Ocean during peak glacial conditions, a hypothesis proposed nearly half a century ago, and how groundwater escape features are visible in high-resolution bathymetry in the Baltic Sea, with potential implications for the freshwater budget and distribution of nutrients and pollutants. Presented examples will be placed in the context of mapping resolution, systematic surveys versus mapping along transits, and scientific hypothesis driven mapping versus ocean exploration. The newly announced Nippon Foundation - GEBCO Seabed 2030 project has the vision to map 100% of the World Ocean floor mapped by 2030. Are there specific scientific areas where we can expect new discoveries from all mapping data collected through the Seabed 2030 project? Are there outstanding hypothesis that can be tested from a fully mapped World Ocean floor?

High-resolution onshore-offshore morpho-bathymetric records of modern chalk and granitic shore platforms in NW France

Science.gov (United States)

Duperret, Anne; Raimbault, Céline; Le Gall, Bernard; Authemayou, Christine; van Vliet-Lanoë, Brigitte; Regard, Vincent; Dromelet, Elsa; Vandycke, Sara

2016-07-01

Modern shore platforms developed on rocky coasts are key areas for understanding coastal erosion processes during the Holocene. This contribution offers a detailed picture of two contrasted shore-platform systems, based on new high-resolution shallow-water bathymetry, further coupled with aerial LiDAR topography. Merged land-sea digital elevation models were achieved on two distinct types of rocky coasts along the eastern English Channel in France (Picardy and Upper-Normandy: PUN) and in a NE Atlantic area (SW Brittany: SWB) in NW France. About the PUN case, submarine steps, identified as paleo-shorelines, parallel the actual coastline. Coastal erosive processes appear to be continuous and regular through time, since mid-Holocene at least. In SWB, there is a discrepancy between contemporary coastline orientation and a continuous step extending from inland to offshore, identified as a paleo-shoreline. This illustrates a polyphased and inherited shore platform edification, mainly controlled by tectonic processes.

United States Interagency Elevation Inventory (USIEI)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The U.S. Interagency Elevation Inventory displays high-accuracy topographic and bathymetric data for the United States and its territories. The project is a...

San Francisco Bay Interferometric Bathymetry: Area B

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — High resolution sonar data were collected over ultra-shallow areas of the San Francisco Bay estuary system. Bathymetric and acoustic backscatter data were collected...

Observation of a High Performance Operating Regime with Small Edge-Localized Modes in the National Spherical Torus Experiment

International Nuclear Information System (INIS)

Maingi, R.; Tritz, K.; Fredrickson, E.D.; Menard, J.E.; Sabbagh, S.A.; Stutman, D.; Bell, M.G.; Bell, R.E.; Bush, C.E.; Gates, D.A.; Johnson, D.W.; Kaita, R.; Kaye, S.M.; Kugel, H.W.; LeBlanc, B.P.; Mueller, D.; Raman, R.; Roquemore, A.L.; Soukhanovskii, V.A.

2004-01-01

We report observation of a high performance scenario in the National Spherical Torus Experiment with very small edge-localized modes (ELMs). These ELMs have no measurable impact on stored energy and are consistent with high bootstrap current operation with line average density approaching Greenwald scaling. The ELM perturbation is observed to typically originate near the lower divertor region, as opposed to the outer midplane for ELMs described in the literature. If extrapolable, this scenario would provide an attractive operating regime for next step fusion experiments

Atom localization with double-cascade configuration

International Nuclear Information System (INIS)

Gordeev, Maksim Yu; Rozhdestvensky, Yuri V; Efremova, Ekaterina A

2016-01-01

We investigate the one-dimensional (1D) and two-dimensional (2D) atom localization of a four-level system in a double-cascade configuration. We demonstrate the possibility of 1D localization in the field of a standing wave, 2D localization in the field of two standing waves and 2D localization only in the field of running waves by using different configurations of driven waves on transitions. In addition, for each configuration we reached a high-precision atom localization in one of the states at scales much smaller than the wavelength of the incident optical radiation. (paper)

Assessment of local variability by high-throughput e-beam metrology for prediction of patterning defect probabilities

Science.gov (United States)

Wang, Fuming; Hunsche, Stefan; Anunciado, Roy; Corradi, Antonio; Tien, Hung Yu; Tang, Peng; Wei, Junwei; Wang, Yongjun; Fang, Wei; Wong, Patrick; van Oosten, Anton; van Ingen Schenau, Koen; Slachter, Bram

2018-03-01

We present an experimental study of pattern variability and defectivity, based on a large data set with more than 112 million SEM measurements from an HMI high-throughput e-beam tool. The test case is a 10nm node SRAM via array patterned with a DUV immersion LELE process, where we see a variation in mean size and litho sensitivities between different unique via patterns that leads to a seemingly qualitative differences in defectivity. The large available data volume enables further analysis to reliably distinguish global and local CDU variations, including a breakdown into local systematics and stochastics. A closer inspection of the tail end of the distributions and estimation of defect probabilities concludes that there is a common defect mechanism and defect threshold despite the observed differences of specific pattern characteristics. We expect that the analysis methodology can be applied for defect probability modeling as well as general process qualification in the future.

Impact of MAC Delay on AUV Localization: Underwater Localization Based on Hyperbolic Frequency Modulation Signal.

Science.gov (United States)

Kim, Sungryul; Yoo, Younghwan

2018-01-26

Medium Access Control (MAC) delay which occurs between the anchor node's transmissions is one of the error sources in underwater localization. In particular, in AUV localization, the MAC delay significantly degrades the ranging accuracy. The Cramer-Rao Low Bound (CRLB) definition theoretically proves that the MAC delay significantly degrades the localization performance. This paper proposes underwater localization combined with multiple access technology to decouple the localization performance from the MAC delay. Towards this goal, we adopt hyperbolic frequency modulation (HFM) signal that provides multiplexing based on its good property, high-temporal correlation. Owing to the multiplexing ability of the HFM signal, the anchor nodes can transmit packets without MAC delay, i.e., simultaneous transmission is possible. In addition, the simulation results show that the simultaneous transmission is not an optional communication scheme, but essential for the localization of mobile object in underwater.

COMBO-FISH Enables High Precision Localization Microscopy as a Prerequisite for Nanostructure Analysis of Genome Loci

Directory of Open Access Journals (Sweden)

Rainer Kaufmann

2010-10-01

Full Text Available With the completeness of genome databases, it has become possible to develop a novel FISH (Fluorescence in Situ Hybridization technique called COMBO-FISH (COMBinatorial Oligo FISH. In contrast to other FISH techniques, COMBO-FISH makes use of a bioinformatics approach for probe set design. By means of computer genome database searching, several oligonucleotide stretches of typical lengths of 15–30 nucleotides are selected in such a way that all uniquely colocalize at the given genome target. The probes applied here were Peptide Nucleic Acids (PNAs—synthetic DNA analogues with a neutral backbone—which were synthesized under high purity conditions. For a probe repetitively highlighted in centromere 9, PNAs labeled with different dyes were tested, among which Alexa 488Ò showed reversible photobleaching (blinking between dark and bright state a prerequisite for the application of SPDM (Spectral Precision Distance/Position Determination Microscopy a novel technique of high resolution fluorescence localization microscopy. Although COMBO-FISH labeled cell nuclei under SPDM conditions sometimes revealed fluorescent background, the specific locus was clearly discriminated by the signal intensity and the resulting localization accuracy in the range of 10–20 nm for a detected oligonucleotide stretch. The results indicate that COMBO-FISH probes with blinking dyes are well suited for SPDM, which will open new perspectives on molecular nanostructural analysis of the genome.

Local acceptance of existing biogas plants in Switzerland

International Nuclear Information System (INIS)

Soland, Martin; Steimer, Nora; Walter, Götz

2013-01-01

After the Swiss government's decision to decommission its five nuclear power plants by 2035, energy production from wind, biomass, biogas and photovoltaic is expected to increase significantly. Due to its many aspects of a direct democracy, high levels of public acceptance are necessary if a substantial increase in new renewable energy power plants is to be achieved in Switzerland. A survey of 502 citizens living near 19 biogas plants was conducted as the basis for using structural equation modeling to measure the effects of perceived benefits, perceived costs, trust towards the plant operator, perceived smell, information received and participation options on citizens’ acceptance of “their” biogas plant. Results show that local acceptance towards existing biogas power plants is relatively high in Switzerland. Perceived benefits and costs as well as trust towards the plant operator are highly correlated and have a significant effect on local acceptance. While smell perception and information received had a significant effect on local acceptance as well, no such effect was found for participation options. Reasons for the non-impact of participation options on local acceptance are discussed, and pathways for future research are presented. - Highlights: • Acceptance of biogas plants by local residents in Switzerland is relatively high. • Local acceptance is highly affected by perceived outcomes and citizens’ trust. • Smell perception increases perceived costs and reduces perceived benefits and trust. • Information offers reduce perceived costs and increase trust and perceived benefits. • Participation offers do not have any effect on local acceptance

Local Identity of No-Fee Preservice Students and Its Impact on Their Localized Professional Orientation

Science.gov (United States)

Yang, Ze; Li, Ling; Zhu, Chengchen; Guo, Lexiang; Huang, Liangyong

2013-01-01

Based on analysis of the responses of 359 no-fee preservice students, this study found that: (1) Local identity includes the living environment, cultural environment, people, behavior, economic identity, and sense of alienation associated with one's home place. (2) Local identity is relatively high overall, but identity with behavior at home and…

High frequency source localization in a shallow ocean sound channel using frequency difference matched field processing.

Science.gov (United States)

Worthmann, Brian M; Song, H C; Dowling, David R

2015-12-01

Matched field processing (MFP) is an established technique for source localization in known multipath acoustic environments. Unfortunately, in many situations, particularly those involving high frequency signals, imperfect knowledge of the actual propagation environment prevents accurate propagation modeling and source localization via MFP fails. For beamforming applications, this actual-to-model mismatch problem was mitigated through a frequency downshift, made possible by a nonlinear array-signal-processing technique called frequency difference beamforming [Abadi, Song, and Dowling (2012). J. Acoust. Soc. Am. 132, 3018-3029]. Here, this technique is extended to conventional (Bartlett) MFP using simulations and measurements from the 2011 Kauai Acoustic Communications MURI experiment (KAM11) to produce ambiguity surfaces at frequencies well below the signal bandwidth where the detrimental effects of mismatch are reduced. Both the simulation and experimental results suggest that frequency difference MFP can be more robust against environmental mismatch than conventional MFP. In particular, signals of frequency 11.2 kHz-32.8 kHz were broadcast 3 km through a 106-m-deep shallow ocean sound channel to a sparse 16-element vertical receiving array. Frequency difference MFP unambiguously localized the source in several experimental data sets with average peak-to-side-lobe ratio of 0.9 dB, average absolute-value range error of 170 m, and average absolute-value depth error of 10 m.

Local equilibrium

Energy Technology Data Exchange (ETDEWEB)

Anon.

1984-12-15

From 3-6 September the First International Workshop on Local Equilibrium in Strong Interaction Physics took place in Bad-Honnef at the Physics Centre of the German Physical Society. A number of talks covered the experimental and theoretical investigation of the 'hotspots' effect, both in high energy particle physics and in intermediate energy nuclear physics.

How High Local Charge Carrier Mobility and an Energy Cascade in a Three-Phase Bulk Heterojunction Enable >90% Quantum Efficiency

KAUST Repository

Burke, Timothy M.

2013-12-27

Charge generation in champion organic solar cells is highly efficient in spite of low bulk charge-carrier mobilities and short geminate-pair lifetimes. In this work, kinetic Monte Carlo simulations are used to understand efficient charge generation in terms of experimentally measured high local charge-carrier mobilities and energy cascades due to molecular mixing. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

How High Local Charge Carrier Mobility and an Energy Cascade in a Three-Phase Bulk Heterojunction Enable >90% Quantum Efficiency

KAUST Repository

Burke, Timothy M.; McGehee, Michael D.

2013-01-01

Charge generation in champion organic solar cells is highly efficient in spite of low bulk charge-carrier mobilities and short geminate-pair lifetimes. In this work, kinetic Monte Carlo simulations are used to understand efficient charge generation in terms of experimentally measured high local charge-carrier mobilities and energy cascades due to molecular mixing. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Locally Linear Embedding of Local Orthogonal Least Squares Images for Face Recognition

Science.gov (United States)

Hafizhelmi Kamaru Zaman, Fadhlan

2018-03-01

Dimensionality reduction is very important in face recognition since it ensures that high-dimensionality data can be mapped to lower dimensional space without losing salient and integral facial information. Locally Linear Embedding (LLE) has been previously used to serve this purpose, however, the process of acquiring LLE features requires high computation and resources. To overcome this limitation, we propose a locally-applied Local Orthogonal Least Squares (LOLS) model can be used as initial feature extraction before the application of LLE. By construction of least squares regression under orthogonal constraints we can preserve more discriminant information in the local subspace of facial features while reducing the overall features into a more compact form that we called LOLS images. LLE can then be applied on the LOLS images to maps its representation into a global coordinate system of much lower dimensionality. Several experiments carried out using publicly available face datasets such as AR, ORL, YaleB, and FERET under Single Sample Per Person (SSPP) constraint demonstrates that our proposed method can reduce the time required to compute LLE features while delivering better accuracy when compared to when either LLE or OLS alone is used. Comparison against several other feature extraction methods and more recent feature-learning method such as state-of-the-art Convolutional Neural Networks (CNN) also reveal the superiority of the proposed method under SSPP constraint.

Enhancing the connectivity of high speed rail in the Orlando-Tampa corridor with local public transportation systems : issues and opportunities.

Science.gov (United States)

2011-01-01

High Speed Rail (HSR) will only be truly transformational if it has effective connections with as many other modes of transportation as possible. This project looks at local public transportation systems that have opportunities to connect to HSR stat...

Quantification of tidal inlet morphodynamics using high-resolution MBES and LiDAR

DEFF Research Database (Denmark)

Ernstsen, Verner Brandbyge; Lefebvre, Alice; Fraccascia, Serena

-bathymetric surveys using high-resolution red and green Light Detection And Ranging (LiDAR). Detailed digital elevation models with a grid cell size of 1 m x 1 m were generated and analysed geomorphometrically. The analyses reveal a main ebb-directed net sand transport in the main channel; however, due...... to the geometry of the main channel, displaying a confluent meander bend, confined areas in the main channel are characterised by an opposite-directed net sand transport. In the inter-tidal areas the main net sand transport is flood-directed. However, also here the analyses reveal the existence of oblique second...... is transported from the inlet channel to the intertidal flat. Therefore, in addition to the typical main sand transport directions with net export in the inlet channel and net import over the adjacent inter-tidal flats, these investigations suggest an exchange and possible recirculation of sand between the inlet...

Highly efficient local delivery of endothelial progenitor cells significantly potentiates angiogenesis and full-thickness wound healing.

Science.gov (United States)

Wang, Chenggui; Wang, Qingqing; Gao, Wendong; Zhang, Zengjie; Lou, Yiting; Jin, Haiming; Chen, Xiaofeng; Lei, Bo; Xu, Huazi; Mao, Cong

2018-03-15

Wound therapy with a rapid healing performance remains a critical clinical challenge. Cellular delivery is considered to be a promising approach to improve the efficiency of healing, yet problems such as compromised cell viability and functionality arise due to the inefficient delivery. Here, we report the efficient delivery of endothelial progenitor cells (EPCs) with a bioactive nanofibrous scaffold (composed of collagen and polycaprolactone and bioactive glass nanoparticles, CPB) for enhancing wound healing. Under the stimulation of CPB nanofibrous system, the viability and angiogenic ability of EPCs were significantly enhanced through the activation of Hif-1α/VEGF/SDF-1α signaling. In vivo, CPB/EPC constructs significantly enhanced the formation of high-density blood vessels by greatly upregulating the expressions of Hif-1α, VEGF, and SDF-1α. Moreover, owing to the increased local delivery of cells and fast neovascularization within the wound site, cell proliferative activity, granulation tissue formation, and collagen synthesis and deposition were greatly promoted by CPB/EPC constructs resulting in rapid re-epithelialization and regeneration of skin appendages. As a result, the synergistic enhancement of wound healing was observed from CPB/EPC constructs, which suggests the highly efficient delivery of EPCs. CPB/EPC constructs may become highly competitive cell-based therapeutic products for efficient impaired wound healing application. This study may also provide a novel strategy to develop bioactive cell therapy constructs for angiogenesis-related regenerative medicine. This paper reported a highly efficient local delivery of EPCs using bioactive glass-based CPB nanofibrous scaffold for enhancing angiogenesis and wound regeneration. In vitro study showed that CPB can promote the proliferation, migration, and tube formation of EPCs through upregulation of the Hif-1α/VEGF/SDF-1α signaling pathway, indicating that the bioactivity and angiogenic ability of

Sea-floor morphology and sedimentary environments in western Block Island Sound, offshore of Fishers Island, New York

Science.gov (United States)

McMullen, Katherine Y.; Poppe, Lawrence J.; Danforth, William W.; Blackwood, Dann S.; Winner, William G.; Parker, Castle E.

2015-01-01

Multibeam-bathymetric and sidescan-sonar data, collected by the National Oceanic and Atmospheric Administration in a 114-square-kilometer area of Block Island Sound, southeast of Fishers Island, New York, are combined with sediment samples and bottom photography collected by the U.S. Geological Survey from 36 stations in this area in order to interpret sea-floor features and sedimentary environments. These interpretations and datasets provide base maps for studies on benthic ecology and resource management. The geologic features and sedimentary environments on the sea floor are products of the area’s glacial history and modern processes. These features include bedrock, drumlins, boulders, cobbles, large current-scoured bathymetric depressions, obstacle marks, and glaciolacustrine sediments found in high-energy sedimentary environments of erosion or nondeposition; and sand waves and megaripples in sedimentary environments characterized by coarse-grained bedload transport. Trawl marks are preserved in lower energy environments of sorting and reworking. This report releases the multibeam-bathymetric, sidescan-sonar, sediment, and photographic data and interpretations of the features and sedimentary environments in Block Island Sound, offshore Fishers Island.

Analysis of seafloor change at Breton Island, Gosier Shoals, and surrounding waters, 1869–2014, Breton National Wildlife Refuge, Louisiana

Science.gov (United States)

Flocks, James G.; Terrano, Joseph F.

2016-08-01

Characterizing bathymetric change in coastal environments is an important component in understanding shoreline evolution, especially along barrier island platforms. Bathymetric change is a function of the regional sediment budget, long-term wave and current patterns, and episodic impact from high-energy events such as storms. Human modifications may also cause changes in seafloor elevation. This study, conducted by the U.S. Geological Survey in collaboration with the U.S. Fish and Wildlife Service, evaluates bathymetric and volumetric change and sediment characteristics around Breton Island and Gosier Shoals located offshore of the Mississippi River Delta in Louisiana. This area has been affected by significant storm events such as Hurricane Katrina in 2005. Sedimentation patterns at Breton Island and offshore have also been modified by the excavation of a shipping channel north of the island. Four time periods are considered that encompass these episodes and include long-term change and short-term storm recovery: 1869–2014, 1869–1920, 1920–2014, and 2007–2014. Finally, sediment characteristics are reported in the context of seafloor elevation.

Design and implementation of interface units for high speed fiber optics local area networks and broadband integrated services digital networks

Science.gov (United States)

Tobagi, Fouad A.; Dalgic, Ismail; Pang, Joseph

1990-01-01

The design and implementation of interface units for high speed Fiber Optic Local Area Networks and Broadband Integrated Services Digital Networks are discussed. During the last years, a number of network adapters that are designed to support high speed communications have emerged. This approach to the design of a high speed network interface unit was to implement package processing functions in hardware, using VLSI technology. The VLSI hardware implementation of a buffer management unit, which is required in such architectures, is described.

Strategy for Developing Local Chicken

Directory of Open Access Journals (Sweden)

Sofjan Iskandar

2006-12-01

Full Text Available Chicken industry in Indonesia offer jobs for people in the village areas . The balance in development industry of selected and local chicken has to be anticipated as there has been threat of reducing importation of grand parent stock of selected chicken due to global avian influenza . In the mean time, high appreciation to the local chicken has been shown by the existence of local chicken farms in the size of business scale . For local chicken business, the government has been built programs, projects, and infrastructures, although the programs and projects were dropped scattered in to several institutions, which were end up with less significant impact to the people. Therefore, it is the time that the government should put more efforts to integrate various sources . focusing in enhancing local chicken industry .

Submerged Humid Tropical Karst Landforms Observed By High-Resolution Multibeam Survey in Nagura Bay, Ishigaki Island, Southwestern Japan

Science.gov (United States)

Kan, H.; Urata, K.; Nagao, M.; Hori, N.; Fujita, K.; Yokoyama, Y.; Nakashima, Y.; Ohashi, T.; Goto, K.; Suzuki, A.

2014-12-01

Submerged tropical karst features were discovered in Nagura Bay on Ishigaki Island in the South Ryukyu Islands, Japan. This is the first description of submerged humid tropical karst using multibeam bathymetry. We conducted a broadband multibeam survey in the central area of Nagura Bay (1.85 × 2.7 km) and visualized the high-resolution bathymetric results with a grid size of 1 m over a depth range of 1.6-58.5 m. Various types of humid tropical karst landforms were found to coexist within the bay, including fluviokarst, doline karst, cockpit karst, polygonal karst, uvalas, and mega-dolines. We assume that Nagura Bay was a large karst basin in which older limestone remained submerged, thus preventing corrosion and the accumulation of reef sediments during periods of submersion, whereas the limestone outcropping on land was corroded during multiple interglacial and glacial periods. Based on our bathymetric result together with aerial photographs of the coastal area, we conclude that the submerged karst landscape has likely developed throughout the whole of Nagura Bay, covering an area of ~6 × 5 km. Accordingly, this area hosts the largest submerged karst in Japan. We also observed abundant coral communities during our SCUBA observations. The present marine conditions of Nagura Bay are characterized by low energy (calm sea) and low irradiance owing to the terrestrial influence. Such conditions have been emphasized by the presence of large undulating landforms, which cause decreases in wave intensity and irradiance with depth. These characteristics have acted to establish unique conditions compared to other coral reef areas in the Ryukyu Islands. It may play an important role in supporting the regional coral reef ecosystem.

SUBMARINE MASS MOVEMENT AND LOCALIZED TSUNAMI POTENTIALITY OF MENTAWAI BASIN, SUMATERA, INDONESIA

Directory of Open Access Journals (Sweden)

Haryadi Permana

2017-07-01

Full Text Available The new bathymetry and seismic data were acquired during the PreTI-Gap marine survey (February 15 to March 6, 2008. The survey was carried out along the NE margin of Mentawai Island using multi-beam swath bathymetry equipment, and 28-channels seismic streamer and four-airgun source. The first target was the Mega Island region near the epicenter of the 2007 great earthquake. The shallow bathymetry is characterized as a flat coral platform suggesting that 200 km elongated plateau is slowly subsiding without any active faults. Further north, from South Pagai to North of Siberut Islands, the seafloor morphology changes significantly. The deep and wide canyons or valleys produce very rough seafloor morphology between 50 and 1100 m water depth. In general, the submarine topography shows two break slopes at different depths. Between slope breaks, the undulating, hilly and circular features dominate, possibly caused by mass movement. A push-up ridge is observed that dams the sediments eroded within a steep slope northeastward side. The seismic reflection data acquired along 14 dip seismic lines at the NE flank of Mentawai Islands, from Siberut to the South of Pagai Islands. We observed a set of southwestward dipping back thrust bounding the NE margin of the Mentawai Island and the push-up ridge observed on bathymetric image, which suggest that Mentawai fault is not pure a strike slip fault, but consists of a set of back thrusts. Such kind of back thrust movement at the flank of Mentawai basin can trigger mass movement or landslide that can produce localized tsunami causing damages to Sumatera mainland such as Padang, Painan or northern Bengkulu provinces and Mentawai Islands. Therefore, it is important to re-design the tsunami warning system, especially in this region, in order to mitigate tsunami risk to coastal region of western Sumatera.

Local dependency in networks

Directory of Open Access Journals (Sweden)

Kudĕlka Miloš

2015-06-01

Full Text Available Many real world data and processes have a network structure and can usefully be represented as graphs. Network analysis focuses on the relations among the nodes exploring the properties of each network. We introduce a method for measuring the strength of the relationship between two nodes of a network and for their ranking. This method is applicable to all kinds of networks, including directed and weighted networks. The approach extracts dependency relations among the network’s nodes from the structure in local surroundings of individual nodes. For the tasks we deal with in this article, the key technical parameter is locality. Since only the surroundings of the examined nodes are used in computations, there is no need to analyze the entire network. This allows the application of our approach in the area of large-scale networks. We present several experiments using small networks as well as large-scale artificial and real world networks. The results of the experiments show high effectiveness due to the locality of our approach and also high quality node ranking comparable to PageRank.

Development of localized arc filament RF plasma actuators for high-speed and high Reynolds number flow control

International Nuclear Information System (INIS)

Kim, J.-H.; Nishihara, M.; Adamovich, I.V.; Samimy, M.; Gorbatov, S.V.; Pliavaka, F.V.

2010-01-01

Recently developed localized arc filament plasma actuators (LAFPAs) have shown tremendous control authority in high-speed and high Reynolds number flow for mixing enhancement and noise mitigation. Previously, these actuators were powered by a high-voltage pulsed DC plasma generator with low energy coupling efficiency of 5-10%. In the present work, a new custom-designed 8-channel pulsed radio frequency (RF) plasma generator has been developed to power up to 8 plasma actuators operated over a wide range of forcing frequencies (up to 50 kHz) and duty cycles (1-50%), and at high energy coupling efficiency (up to 80-85%). This reduces input electrical power requirements by approximately an order of magnitude, down to 12 W per actuator operating at 10% duty cycle. The new pulsed RF plasma generator is scalable to a system with a large number of channels. Performance of pulsed RF plasma actuators used for flow control was studied in a Mach 0.9 circular jet with a Reynolds number of about 623,000 and compared with that of pulsed DC actuators. Eight actuators were distributed uniformly on the perimeter of a 2.54-cm diameter circular nozzle extension. Both types of actuators coupled approximately the same amount of power to the flow, but with drastically different electrical inputs to the power supplies. Particle image velocimetry measurements showed that jet centerline Mach number decay produced by DC and RF actuators operating at the same forcing frequencies and duty cycles is very similar. At a forcing Strouhal number near 0.3, close to the jet column instability frequency, well-organized periodic structures, with similar patterns and dimensions, were generated in the jets forced by both DC and RF actuators. Far-field acoustic measurements demonstrated similar trends in the overall sound pressure level (OASPL) change produced by both types of actuators, resulting in OASPL reduction up to 1.2-1.5 dB in both cases. We conclude that pulsed RF actuators demonstrate flow

Revealing the local properties of beta-HP4N7, a promising candidate for high pressure synthesis of new materials

Czech Academy of Sciences Publication Activity Database

Morales-García, A.; del Corro, Elena

2015-01-01

Roč. 2, č. 4 (2015), č. článku 045904. ISSN 2053-1591 Institutional support: RVO:61388955 Keywords : initio molecular-dynamics * high pressure * qtaim * phase transition * local properties Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.968, year: 2015

Simulations of ultra-high energy cosmic rays in the local Universe and the origin of cosmic magnetic fields

Science.gov (United States)

Hackstein, S.; Vazza, F.; Brüggen, M.; Sorce, J. G.; Gottlöber, S.

2018-04-01

We simulate the propagation of cosmic rays at ultra-high energies, ≳1018 eV, in models of extragalactic magnetic fields in constrained simulations of the local Universe. We use constrained initial conditions with the cosmological magnetohydrodynamics code ENZO. The resulting models of the distribution of magnetic fields in the local Universe are used in the CRPROPA code to simulate the propagation of ultra-high energy cosmic rays. We investigate the impact of six different magneto-genesis scenarios, both primordial and astrophysical, on the propagation of cosmic rays over cosmological distances. Moreover, we study the influence of different source distributions around the Milky Way. Our study shows that different scenarios of magneto-genesis do not have a large impact on the anisotropy measurements of ultra-high energy cosmic rays. However, at high energies above the Greisen-Zatsepin-Kuzmin (GZK)-limit, there is anisotropy caused by the distribution of nearby sources, independent of the magnetic field model. This provides a chance to identify cosmic ray sources with future full-sky measurements and high number statistics at the highest energies. Finally, we compare our results to the dipole signal measured by the Pierre Auger Observatory. All our source models and magnetic field models could reproduce the observed dipole amplitude with a pure iron injection composition. Our results indicate that the dipole is observed due to clustering of secondary nuclei in direction of nearby sources of heavy nuclei. A light injection composition is disfavoured, since the increase in dipole angular power from 4 to 8 EeV is too slow compared to observation by the Pierre Auger Observatory.

Efficient numerical simulations of many-body localized systems

Energy Technology Data Exchange (ETDEWEB)

Pollmann, Frank [Max-Planck-Institut fuer Physik komplexer Systeme, 01187 Dresden (Germany); Khemani, Vedika; Sondhi, Shivaji [Physics Department, Princeton University, Princeton, NJ 08544 (United States)

2016-07-01

Many-body localization (MBL) occurs in isolated quantum systems when Anderson localization persists in the presence of finite interactions. To understand this phenomenon, the development of new, efficient numerical methods to find highly excited eigenstates is essential. We introduce a variant of the density-matrix renormalization group (DMRG) method that obtains individual highly excited eigenstates of MBL systems to machine precision accuracy at moderate-large disorder. This method explicitly takes advantage of the local spatial structure characterizing MBL eigenstates.

Proton Therapy as Salvage Treatment for Local Relapse of Prostate Cancer Following Cryosurgery or High-Intensity Focused Ultrasound

International Nuclear Information System (INIS)

Holtzman, Adam L.; Hoppe, Bradford S.; Letter, Haley P.; Bryant, Curtis; Nichols, Romaine C.; Henderson, Randal H.; Mendenhall, William M.; Morris, Christopher G.; Williams, Christopher R.; Li, Zuofeng; Mendenhall, Nancy P.

2016-01-01

Purpose: Local recurrence of prostate cancer after cryosurgery (CS) and high-intensity focused ultrasound (HIFU) is an emerging problem for which optimal management is unknown. Proton therapy (PT) may offer advantages over other local therapeutic options. This article reviews a single institution's experience using PT for salvage of local recurrent disease after HIFU or CS. Methods and Materials: We reviewed the medical records of 21 consecutive patients treated with salvage PT following a local recurrence of prostate cancer after CS (n=12) or HIFU (n=9) between January 2007 and July 2014. Patients were treated to a median dose of 74 Gy(relative biological effectiveness [RBE]; range: 74-82 Gy[RBE]) and 8 patients received androgen deprivation therapy with radiation therapy. Patients were evaluated for quality of life (QOL) by using the Expanded Prostate Index Composite questionnaire and toxicity by using Common Terminology Criteria for Adverse Events, version 3.0, weekly during treatment, every 6 months for 2 years after treatment, and then annually. Results: Median follow-up was 37 months (range: 6-95 months). The 3-year biochemical progression-free survival (bPFS) rate was 77%. The 3-year grade 3 toxicity rate was 17%; however, 2 of these patients had pre-existing grade 3 GU toxicities from their HIFU/CRYO prior to PT. At 1 year, bowel summary, urinary incontinence, and urinary obstructive QOL scores declined, but only the bowel QOL score at 12 months met the minimally important difference threshold. Conclusions: PT achieved a high rate of bPFS with acceptable toxicity and minimal changes in QOL scores compared with baseline pre-PT functions. Although most patients have done fairly well, the study size is small, follow-up is short, and early results suggest that outcomes with PT for salvage after HIFU or CS failure are inferior to outcomes with PT given in the de novo setting with respect to disease control, toxicity, and QOL.

Proton Therapy as Salvage Treatment for Local Relapse of Prostate Cancer Following Cryosurgery or High-Intensity Focused Ultrasound

Energy Technology Data Exchange (ETDEWEB)

Holtzman, Adam L. [University of Florida Health Proton Therapy Institute, University of Florida College of Medicine, Jacksonville, Florida (United States); Hoppe, Bradford S., E-mail: bhoppe@floridaproton.org [University of Florida Health Proton Therapy Institute, University of Florida College of Medicine, Jacksonville, Florida (United States); Letter, Haley P.; Bryant, Curtis; Nichols, Romaine C.; Henderson, Randal H.; Mendenhall, William M.; Morris, Christopher G. [University of Florida Health Proton Therapy Institute, University of Florida College of Medicine, Jacksonville, Florida (United States); Williams, Christopher R. [Department of Surgery, University of Florida College of Medicine, Jacksonville, Florida (United States); Li, Zuofeng; Mendenhall, Nancy P. [University of Florida Health Proton Therapy Institute, University of Florida College of Medicine, Jacksonville, Florida (United States)

2016-05-01

Purpose: Local recurrence of prostate cancer after cryosurgery (CS) and high-intensity focused ultrasound (HIFU) is an emerging problem for which optimal management is unknown. Proton therapy (PT) may offer advantages over other local therapeutic options. This article reviews a single institution's experience using PT for salvage of local recurrent disease after HIFU or CS. Methods and Materials: We reviewed the medical records of 21 consecutive patients treated with salvage PT following a local recurrence of prostate cancer after CS (n=12) or HIFU (n=9) between January 2007 and July 2014. Patients were treated to a median dose of 74 Gy(relative biological effectiveness [RBE]; range: 74-82 Gy[RBE]) and 8 patients received androgen deprivation therapy with radiation therapy. Patients were evaluated for quality of life (QOL) by using the Expanded Prostate Index Composite questionnaire and toxicity by using Common Terminology Criteria for Adverse Events, version 3.0, weekly during treatment, every 6 months for 2 years after treatment, and then annually. Results: Median follow-up was 37 months (range: 6-95 months). The 3-year biochemical progression-free survival (bPFS) rate was 77%. The 3-year grade 3 toxicity rate was 17%; however, 2 of these patients had pre-existing grade 3 GU toxicities from their HIFU/CRYO prior to PT. At 1 year, bowel summary, urinary incontinence, and urinary obstructive QOL scores declined, but only the bowel QOL score at 12 months met the minimally important difference threshold. Conclusions: PT achieved a high rate of bPFS with acceptable toxicity and minimal changes in QOL scores compared with baseline pre-PT functions. Although most patients have done fairly well, the study size is small, follow-up is short, and early results suggest that outcomes with PT for salvage after HIFU or CS failure are inferior to outcomes with PT given in the de novo setting with respect to disease control, toxicity, and QOL.

High-resolution Local Gravity Model of the South Pole of the Moon from GRAIL Extended Mission Data

Science.gov (United States)

Goossens, Sander Johannes; Sabaka, Terence J.; Nicholas, Joseph B.; Lemoine, Frank G.; Rowlands, David D.; Mazarico, Erwan; Neumann, Gregory A.; Smith, David E.; Zuber, Maria T.

2014-01-01

We estimated a high-resolution local gravity field model over the south pole of the Moon using data from the Gravity Recovery and Interior Laboratory's extended mission. Our solution consists of adjustments with respect to a global model expressed in spherical harmonics. The adjustments are expressed as gridded gravity anomalies with a resolution of 1/6deg by 1/6deg (equivalent to that of a degree and order 1080 model in spherical harmonics), covering a cap over the south pole with a radius of 40deg. The gravity anomalies have been estimated from a short-arc analysis using only Ka-band range-rate (KBRR) data over the area of interest. We apply a neighbor-smoothing constraint to our solution. Our local model removes striping present in the global model; it reduces the misfit to the KBRR data and improves correlations with topography to higher degrees than current global models.

Seeing the Forest and the Trees: Default Local Processing in Individuals with High Autistic Traits Does Not Come at the Expense of Global Attention.

Science.gov (United States)

Stevenson, Ryan A; Sun, Sol Z; Hazlett, Naomi; Cant, Jonathan S; Barense, Morgan D; Ferber, Susanne

2018-04-01

Atypical sensory perception is one of the most ubiquitous symptoms of autism, including a tendency towards a local-processing bias. We investigated whether local-processing biases were associated with global-processing impairments on a global/local attentional-scope paradigm in conjunction with a composite-face task. Behavioural results were related to individuals' levels of autistic traits, specifically the Attention to Detail subscale of the Autism Quotient, and the Sensory Profile Questionnaire. Individuals showing high rates of Attention to Detail were more susceptible to global attentional-scope manipulations, suggesting that local-processing biases associated with Attention to Detail do not come at the cost of a global-processing deficit, but reflect a difference in default global versus local bias. This relationship operated at the attentional/perceptual level, but not response criterion.

MR-based source localization for MR-guided HDR brachytherapy

Science.gov (United States)

Beld, E.; Moerland, M. A.; Zijlstra, F.; Viergever, M. A.; Lagendijk, J. J. W.; Seevinck, P. R.

2018-04-01

For the purpose of MR-guided high-dose-rate (HDR) brachytherapy, a method for real-time localization of an HDR brachytherapy source was developed, which requires high spatial and temporal resolutions. MR-based localization of an HDR source serves two main aims. First, it enables real-time treatment verification by determination of the HDR source positions during treatment. Second, when using a dummy source, MR-based source localization provides an automatic detection of the source dwell positions after catheter insertion, allowing elimination of the catheter reconstruction procedure. Localization of the HDR source was conducted by simulation of the MR artifacts, followed by a phase correlation localization algorithm applied to the MR images and the simulated images, to determine the position of the HDR source in the MR images. To increase the temporal resolution of the MR acquisition, the spatial resolution was decreased, and a subpixel localization operation was introduced. Furthermore, parallel imaging (sensitivity encoding) was applied to further decrease the MR scan time. The localization method was validated by a comparison with CT, and the accuracy and precision were investigated. The results demonstrated that the described method could be used to determine the HDR source position with a high accuracy (0.4–0.6 mm) and a high precision (⩽0.1 mm), at high temporal resolutions (0.15–1.2 s per slice). This would enable real-time treatment verification as well as an automatic detection of the source dwell positions.

Birding for and with People: Integrating Local Participation in Avian Monitoring Programs within High Biodiversity Areas in Southern Mexico

Directory of Open Access Journals (Sweden)

Humberto Berlanga

2012-08-01

Full Text Available Biological monitoring is a powerful tool for understanding ecological patterns and processes, implementing sound management practices, and determining wildlife conservation strategies. In Mexico, regional long-term bird monitoring has been undertaken only over the last decade. Two comprehensive programs have incorporated bird monitoring as the main tool for assessing the impact of human productive activities on birds and habitats at local and regional levels: the Integrated Ecosystem Management (IEM and the Mesoamerican Biological Corridor Mexico (CBMM. These programs are implemented in supremely important biodiverse regions in the southern and southeastern states of Mexico. Bird monitoring activities are based on the recruitment and participation of local people linked to sustainable productive projects promoted by the CBMM or IEM. Through a series of training workshops delivered by specialists, local monitors receive equipment and coordinate to become part of a large monitoring network that facilitates regional covertures. This data currently being obtained by local people will enable the mid- and long-term assessment of the impacts of sustainable human productive activities on birds and biodiversity. Community-based bird monitoring programs are a promising opportunity for enhancing scientific knowledge, improving sustainable practices, and supporting wildlife conservation in areas of high biodiversity.

Local electromagnetic waves in layered superconductors

International Nuclear Information System (INIS)

Gvozdikov, V.M.; Vega-Monroy, R.

1999-01-01

A dispersion equation for electromagnetic waves localized on a defect layer of a layered superconductor is obtained in the frame of a model which neglects electron hopping between layers but assumes an arbitrary current-current response function within the layers. The defect layer differs from the rest of the layers by density and mass of charge carriers. It is shown that near the critical temperature in the London limit the local mode lies within the superconducting gap and has a wave vector threshold depending on the layered crystal and defect layer parameters. In the case of highly anisotropic layered superconductors, like Bi- or Tl-based high-T c cuprates, the local mode exists within a narrow range of positive variations of the mass and charge carriers. (author)

High resolution method for the magnetic axis localization for multipole magnets on the base of the garnet films technology

International Nuclear Information System (INIS)

Gertsev, K.F.; Gribkov, V.L.; Liskov, V.A.; Chervonenkis, A.J.

1992-01-01

The methods of stretched wires for the localization of the magnetic axis may be inconvenient sometimes in accelerators and colliders of very high energies because of high gradients, large lengths and small apertures. High gradients may deform the wires due to the nonzero magnetic susceptibility and microscopic ferromagnetic particles on their surface. Long wires have large sagittas and small apertures of magnets limit the transversal working domains for the measuring devices. Precision optics magnets possess extreme parameters, in particular, in interaction regions. The magneto-optic (MO) methods of the measurements present some new possibilities for the solution of the above problems. The use of MO films for magnetic field visualization and mapping was proposed and shown that on the basis of Bi-substituted iron garnet films and MO Faraday effect it's possible to obtain the quantitative vector maps of complicated magnetic field structure. Later this was described on a large scale. This method was discussed in terms of its applicability to the magnetic axis localization in quadrupoles of accelerators. In our opinion, the films technology has great advantages as compared with the colloidal solution. In this paper the principles and variants of the films method are presented and further development of the method under discussion is described

Regional and local meteorology influences high-resolution tropospheric ozone concentration in the Los Angeles Basin

Science.gov (United States)

Koutzoukis, S.; Jenerette, D.; Chandler, M.; Wang, J.; Ge, C.; Ripplinger, J.

2017-12-01

Urban air quality and climate directly affect resident health. The Los Angeles (LA) Basin is a highly populated metropolitan area, with widespread point sources of ozone (O3) precursors (NOx , Volatile Organic Compounds, CO) from fossil fuel combustion. The LA basin exists on a coast-to-mountain gradient, with increasing temperatures towards the Transverse Ranges, which rise to 1700m. Frequently not compliant with 8-hour O3 standards, the LA and South Coast Air Basins are designated as severe and extreme non-attainment areas. Summer weather in the LA basin is characterized by a persistent high pressure system, creating an inversion that traps air pollutants, including O3 precursors, coupled with physical geography that blocks prevailing upper atmosphere air flow. These interactions make neighborhood-level O3 levels more variable than common regional models. Over the summer of 2017, we investigated the importance of local meteorology, wind patterns and air temperature, in transporting and mixing ozone precursors from point sources along the coast-to-mountain gradient. We deployed a network of six EPA federal equivalent method ozone and meteorological sensors in three campaigns in the LA basin along the coast-to-mountain transect. Each campaign, we collaborated with citizen scientists to deploy three sensor stations in two, 4 km2 quadrats, for a total of six high-resolution 4 km2 pixels. O3 concentrations vary greatly along the transect. At the coastal sites, daily O3 ranges from 0ppm to 60ppm and the range increases at the inland sites, to 100ppm. At all sites, there was a positive relationship between wind speed, air temperature, and O3 concentration, with increasing correlation inland. The Pearson correlation coefficient between wind speed and O3 concentration doubles from the coast to inland, and triples between air temperature and O3. The site-specific relationships between O3 and wind direction and temperature vary, suggesting neighborhood-effects from local

High-Dose-Rate Brachytherapy Alone for Localized Prostate Cancer in Patients at Moderate or High Risk of Biochemical Recurrence

Energy Technology Data Exchange (ETDEWEB)

Hoskin, Peter [Cancer Centre, Mount Vernon Hospital, Northwood, Middlesex (United Kingdom); Rojas, Ana, E-mail: arc03@btconnect.com [Cancer Centre, Mount Vernon Hospital, Northwood, Middlesex (United Kingdom); Lowe, Gerry; Bryant, Linda; Ostler, Peter; Hughes, Rob; Milner, Jessica; Cladd, Helen [Cancer Centre, Mount Vernon Hospital, Northwood, Middlesex (United Kingdom)

2012-03-15

Purpose: To evaluate genitourinary (GU) and gastrointestinal (GI) morbidity and biochemical control of disease in patients with localized prostate adenocarcinoma treated with escalating doses per fraction of high-dose rate brachytherapy alone. Methods and Materials: A total of 197 patients were treated with 34 Gy in four fractions, 36 Gy in four fractions, 31.5 Gy in three fractions, or 26 Gy in two fractions. Median follow-up times were 60, 54, 36, and 6 months, respectively. Results: Incidence of early Grade {>=} 3 GU morbidity was 3% to 7%, and Grade 4 was 0% to 4%. During the first 12 weeks, the highest mean International Prostate Symptom Score (IPSS) value was 14, and between 6 months and 5 years it was 8. Grade 3 or 4 early GI morbidity was not observed. The 3-year actuarial rate of Grade 3 GU was 3% to 16%, and was 3% to 7% for strictures requiring surgery (4-year rate). An incidence of 1% Grade 3 GI events was seen at 3 years. Late Grade 4 GU or GI events were not observed. At 3 years, 99% of patients with intermediate-risk and 91% with high-risk disease were free of biochemical relapse (log-rank p = 0.02). Conclusions: There was no significant difference in urinary and rectal morbidity between schedules. Biochemical control of disease in patients with intermediate and high risk of relapse was good.

High speed, locally controlled data acquisition system for TFTR

International Nuclear Information System (INIS)

Feng, H.K.; Bradish, G.J.

1983-01-01

A high speed, locally controlled, data acquisition and transmission system has been developed by the CICADA (Central Instrumentation Control and Data Acquisition) Group for extracting certain timecritical data during a TFTR pulse and passing it to the control room, 1000 feet distant, to satisfy realtime requirements of frequently sampled variables. The system is designed to utilize any or all of the standard CAMAC (Computer Automated Measurement and Control) modules now employed on the CAMAC links for retrieval of the main body of data, but to operate them in a much faster manner than in a standard CAMAC system. To do this, a pre-programmable ROM sequencer is employed as a controller to transmit commands to the modules at intervals down to one microsecond, replacing the usual CAMAC dedicated computer, and increasing the command rate by an order of magnitude over what could be sent down a Branch Highway. Data coming from any number of channels originating within a single CAMAC ''crate'' is then time-multiplexed and transmitted over a single conductor pair in bi-phase at a 2.5 MHz bit rate using Manchester coding techniques. Benefits gained from this approach include: Reduction in the number of conductors required, elimination of line-to-line skew found in parallel transmission systems, and the capability of being transformer coupled or transmitted over a fiber optic cable to avoid safety hazards and ground loops. The main application for this system so far has been as the feedback path in this closed loop control of currents through the Tokamak's field coils. The paper will treat the system's various applications

San Francisco Bay Multi-beam Bathymetry: Area A

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — These multi-beam bathymetric data were collected over shallow subtidal areas in the San Francisco Bay estuary system. Bathymetric and acoustic backscatter data were...

The local phase transitions of the solvent in the neighborhood of a solvophobic polymer at high pressures

Energy Technology Data Exchange (ETDEWEB)

Budkov, Yu. A., E-mail: urabudkov@rambler.ru [G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, Ivanovo (Russian Federation); National Research University Higher School of Economics, Moscow (Russian Federation); Department of Chemistry, Lomonosov Moscow State University, Moscow (Russian Federation); Vyalov, I. I. [Istituto Italiano di Tecnologia, via Morego 30, Genova 16163 (Italy); Kolesnikov, A. L. [Ivanovo State University, Ivanovo (Russian Federation); Institut für Nichtklassische Chemie e.V., Universitat Leipzig, Leipzig (Germany); Georgi, N., E-mail: bancocker@mail.ru [Max Planck Institute for Mathematics in the Sciences, Leipzig (Germany); Chuev, G. N. [Max Planck Institute for the Physics of Complex Systems, Dresden (Germany); Institute of Theoretical and Experimental Biophysics, Russian Academy of Science, Pushchino, Moscow Region (Russian Federation); Kiselev, M. G. [G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, Ivanovo (Russian Federation); Department of Chemistry, Lomonosov Moscow State University, Moscow (Russian Federation)

2014-11-28

We investigate local phase transitions of the solvent in the neighborhood of a solvophobic polymer chain which is induced by a change of the polymer-solvent repulsion and the solvent pressure in the bulk solution. We describe the polymer in solution by the Edwards model, where the conditional partition function of the polymer chain at a fixed radius of gyration is described by a mean-field theory. The contributions of the polymer-solvent and the solvent-solvent interactions to the total free energy are described within the mean-field approximation. We obtain the total free energy of the solution as a function of the radius of gyration and the average solvent number density within the gyration volume. The resulting system of coupled equations is solved varying the polymer-solvent repulsion strength at high solvent pressure in the bulk. We show that the coil-globule (globule-coil) transition occurs accompanied by a local solvent evaporation (condensation) within the gyration volume.

Multibeam mapping of the exclusive economic zone of India

Digital Repository Service at National Institute of Oceanography (India)

Nair, R.R.; Rao, P.S.; Kodagali, V.N.

The seabed in the Exclusive Economic Zone (EEZ) of India is covered with a variety of minerals of economic interest. High resolution bathymetric maps are needed for effective utilisation and management of these resources. To assess the general...

Continental margin of Andhra Pradesh: Some new problems and perspectives

Digital Repository Service at National Institute of Oceanography (India)

Murthy, K.S.R.

the Krishna - Godavari basin and the Nizampatnam Bay. Extensive bathymetric, magnetic, high resolution seismic reflection and gravity data were collected over the margin by the National Institute of Oceanography for the last one decade. Analysis of the data...

Local government and utility firms’ debts

Directory of Open Access Journals (Sweden)

Marko Primorac

2011-12-01

Full Text Available The global financial crisis has affected the Croatian local public sector. In such circumstances, local government units’ debts and borrowing should be approached with caution. The highly interwoven financial operations of local government units and their utilities indicate the need for analysis of consolidated financial statements of local governments and utility companies in order to gain an insight into the real financial “health” of local units. Accordingly, the main aim of this paper is to analyze the size and the structure of the consolidated (local government and utility companies local public debt in Croatia. Accordingly, the paper presents the financial position of local government units supplemented with information on the financial operations of utility companies, with particular emphasis on the size and structure of their liabilities and gross and net debt. Although the current Budget Law does not require formal preparation of consolidated financial statements by local governments and their utility firms, consolidation is stipulated by International Public Sector Accounting Standards (IPSAS. The application of IPSAS regulations would be helpful in determining overall direct and indirect exposure of local government units arising from the financial operations of their utilities.

Local perturbations perturb—exponentially–locally

International Nuclear Information System (INIS)

De Roeck, W.; Schütz, M.

2015-01-01

We elaborate on the principle that for gapped quantum spin systems with local interaction, “local perturbations [in the Hamiltonian] perturb locally [the groundstate].” This principle was established by Bachmann et al. [Commun. Math. Phys. 309, 835–871 (2012)], relying on the “spectral flow technique” or “quasi-adiabatic continuation” [M. B. Hastings, Phys. Rev. B 69, 104431 (2004)] to obtain locality estimates with sub-exponential decay in the distance to the spatial support of the perturbation. We use ideas of Hamza et al. [J. Math. Phys. 50, 095213 (2009)] to obtain similarly a transformation between gapped eigenvectors and their perturbations that is local with exponential decay. This allows to improve locality bounds on the effect of perturbations on the low lying states in certain gapped models with a unique “bulk ground state” or “topological quantum order.” We also give some estimate on the exponential decay of correlations in models with impurities where some relevant correlations decay faster than one would naively infer from the global gap of the system, as one also expects in disordered systems with a localized groundstate

Local control room

CERN Multimedia

CERN PhotoLab

1972-01-01

Local control room in the ejection building : all electronics pertaining to proton distribution and concomitants such as beam gymnastics and diagnostics at high energies will eventually be gathered here. Shown is the first of two rows of fast ejection electronic racks. It includes only what is necessary for operation.

Localization effects in heavy ion collisions

International Nuclear Information System (INIS)

Donangelo, R.J.

1984-01-01

Radial and angular localization in heavy ion reactions on deformed nuclei is discussed. A theoretical method appropriate to study these localization effects is briefly described and then applied to the determination of deformed heavy ion potentials from inclastic scattering data. It is argued that one-and two-nucleon transfer reactions on deformed nuclei can provide a probe of nuclear structure in high angular momentum states and be at least qualitatively analyzed in the light of these localization concepts. (Author) [pt

Localization noise in deep subwavelength plasmonic devices

Science.gov (United States)

Ghoreyshi, Ali; Victora, R. H.

2018-05-01

The grain shape dependence of absorption has been investigated in metal-insulator thin films. We demonstrate that randomness in the size and shape of plasmonic particles can lead to Anderson localization of polarization modes in the deep subwavelength regime. These localized modes can contribute to significant variation in the local field. In the case of plasmonic nanodevices, the effects of the localized modes have been investigated by mapping an electrostatic Hamiltonian onto the Anderson Hamiltonian in the presence of a random vector potential. We show that local behavior of the optical beam can be understood in terms of the weighted local density of the localized modes of the depolarization field. Optical nanodevices that operate on a length scale with high variation in the density of states of localized modes will experience a previously unidentified localized noise. This localization noise contributes uncertainty to the output of plasmonic nanodevices and limits their scalability. In particular, the resulting impact on heat-assisted magnetic recording is discussed.

The 2006 Pingtung Earthquake Doublet Triggered Seafloor Liquefaction: Revisiting the Evidence with Ultra-High-Resolution Seafloor Mapping

Science.gov (United States)

Su, C. C.; Chen, T. T.; Paull, C. K.; Gwiazda, R.; Chen, Y. H.; Lundsten, E. M.; Caress, D. W.; Hsu, H. H.; Liu, C. S.

2017-12-01

Since Heezen and Ewing's (1952) classic work on the 1929 Grand Banks earthquake, the damage of submarine cables have provided critical information on the nature of seafloor mass movements or sediment density flows. However, the understanding of the local conditions that lead to particular seafloor failures earthquakes trigger is still unclear. The Decemeber 26, 2006 Pingtung earthquake doublet which occurred offshore of Fangliao Township, southwestern Taiwan damaged 14 submarine cables between Gaoping slope to the northern terminus of the Manila Trench. Local fisherman reported disturbed waters at the head of the Fangliao submarine canyon, which lead to conjectures that eruptions of mud volcanoes which are common off the southwestern Taiwan. Geophysical survey were conducted to evaluate this area which revealed a series of faults, liquefied strata, pockmarks and acoustically transparent sediments with doming structures which may relate to the submarine groundwater discharge. Moreover, shipboard multi-beam bathymetric survey which was conducted at the east of Fangliao submarine canyon head shows over 10 km2 area with maximum depth around 40 m of seafloor subsidence after Pingtung earthquake. The north end of the subsidence is connected to the Fangliao submarine canyon where the first cable failed after Pingtung earthquake. The evidences suggests the earthquake triggered widespeard liquefaction and generated debris flows within Fangliao submarine canyon. In May 2017, an IONTU-MBARI Joint Survey Cruise (OR1-1163) was conducted on using MBARI Mapping AUV and miniROV to revisit the area where the cable damaged after Pingtung earthquake. From newly collected ultra-high-resolution (1-m lateral resolution) bathymetry data, the stair-stepped morphology is observed at the edge of canyon. The comet-shaped depressions are located along the main headwall of the seafloor failure. The new detailed bathymetry reveal details which suggest Fangliao submarine canyon head is

Lake Bathymetric Aquatic Vegetation

Data.gov (United States)

Minnesota Department of Natural Resources — Aquatic vegetation represented as polygon features, coded with vegetation type (emergent, submergent, etc.) and field survey date. Polygons were digitized from...

Strong Loophole-Free Test of Local Realism.

Science.gov (United States)

Shalm, Lynden K; Meyer-Scott, Evan; Christensen, Bradley G; Bierhorst, Peter; Wayne, Michael A; Stevens, Martin J; Gerrits, Thomas; Glancy, Scott; Hamel, Deny R; Allman, Michael S; Coakley, Kevin J; Dyer, Shellee D; Hodge, Carson; Lita, Adriana E; Verma, Varun B; Lambrocco, Camilla; Tortorici, Edward; Migdall, Alan L; Zhang, Yanbao; Kumor, Daniel R; Farr, William H; Marsili, Francesco; Shaw, Matthew D; Stern, Jeffrey A; Abellán, Carlos; Amaya, Waldimar; Pruneri, Valerio; Jennewein, Thomas; Mitchell, Morgan W; Kwiat, Paul G; Bienfang, Joshua C; Mirin, Richard P; Knill, Emanuel; Nam, Sae Woo

2015-12-18

We present a loophole-free violation of local realism using entangled photon pairs. We ensure that all relevant events in our Bell test are spacelike separated by placing the parties far enough apart and by using fast random number generators and high-speed polarization measurements. A high-quality polarization-entangled source of photons, combined with high-efficiency, low-noise, single-photon detectors, allows us to make measurements without requiring any fair-sampling assumptions. Using a hypothesis test, we compute p values as small as 5.9×10^{-9} for our Bell violation while maintaining the spacelike separation of our events. We estimate the degree to which a local realistic system could predict our measurement choices. Accounting for this predictability, our smallest adjusted p value is 2.3×10^{-7}. We therefore reject the hypothesis that local realism governs our experiment.

Influence of grain structure on quench sensitivity relative to localized corrosion of high strength aluminum alloy

Energy Technology Data Exchange (ETDEWEB)

Liu, ShengDan, E-mail: csuliusd@163.com [School of Materials Science and Engineering, Central South University, Changsha 410083 (China); Key Laboratory of Nonferrous Metal Materials Science and Engineering, Ministry of Education, Changsha 410083 (China); Li, ChengBo [Light Alloy Research Institute, Central South University, Changsha 410083 (China); Deng, YunLai; Zhang, XinMing [School of Materials Science and Engineering, Central South University, Changsha 410083 (China); Key Laboratory of Nonferrous Metal Materials Science and Engineering, Ministry of Education, Changsha 410083 (China)

2015-11-01

The influence of grain structure on quench sensitivity relative to localized corrosion of high strength aluminum alloy 7055 was investigated by electrochemical test, accelerated exfoliation corrosion test, optical microscopy (OM), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and scanning transmission electron microscopy (STEM). The decrease of quench rate led to lower corrosion resistance of both the homogenized and solution heat treated (HS) alloy with equiaxed grains and the hot-rolled and solution heat treated (HRS) alloy with elongated grains, but there was a higher increment in corrosion depth and corrosion current density and a higher decrement in corrosion potential for the latter alloy, which therefore exhibited higher quench sensitivity. It is because in this alloy the larger amount of (sub) grain boundaries led to a higher increment in the amount of quench-induced η phase and precipitates free zone at (sub) grain boundaries with the decrease of quench rate, and there was a larger increment in the content of Zn, Mg and Cu in the η phase at grain boundaries due to slow quenching. The presence of subgrain boundaries in the HRS alloy tended to increase corrosion resistance at high quench rates higher than about 630 °C/min but decrease it at lower quench rates. - Highlights: • (Sub)Grain boundaries increase quench sensitivity relative to localized corrosion. • Subgrain boundaries decrease corrosion resistance below quench rate of 630 °C/min. • More (sub) grain boundaries leads to more GBPs and PFZ with decreasing quench rate.

Feasibility of combined modality therapy for localized high-grade soft tissue sarcomas in adults

International Nuclear Information System (INIS)

Blum, R.H.; Greenberger, J.S.; Wilson, R.E.; Corson, J.M.

1979-01-01

Seventeen consecutive patients with localized, high grade soft tissue sarcomas had resection of their primary tumor, radiation therapy and chemotherapy. The soft tissue sarcoma was primary in 14 patients and regionally recurrent in 3 patients. Chemotherapy consisted of cyclophosphamide 500 mg/M 2 day 1, Adriamycin (ADR) 60 mg/M 2 day 2, and DTIC 400 mg/M 2 days 1 and 2, given every 21 days to a maximum ADR dose of 450 mg/M 2 . Cyclophosphamide and DTIC were then given to a total duration of 1 year. Radiation therapy consisted of 4000 to 5000 rad by megavoltage photons in 5 weeks, and in selected cases, an additional 1500 to 2000 rad by electron beam boost in the tumor bed delivered over 2 additional weeks. Following surgery, 12 patients were treated sequentially with an interval of chemotherapy, radiation therapy and then the completion of chemotherapy. The added morbidity of this sequential approach is minimal: one patient of 12 had delayed primary healing of her wound, 1 of 10 patients required a break in radiation therapy because of skin erythema. Four patients were treated with intensive pre-chemotherapy radiation therapy because of inadequate surgical margins. The median time on study was 18 months from onset of treatment (range, 8 to 41 months). Although there have been no local, regional or distant recurrences, the follow-up time is inadequate to assess the therapeutic benefit of this combined modality treatment

Water sediment, and nutrient budgets, and bathymetric survey of Old and New Gillespie Lakes, Macoupin County, Illinois, May 1996-April 1997; with a discussion of lake-management practices

Science.gov (United States)

Johnson, Gary P.

1999-01-01

The Gillespie Lakes system serves as a drinking water source for the town of Gillespie, Illinois, and is a major recreational focus for the area. As part of an investigation of a concern that the lakes are being adversely affected by excessive sediment and nutrient in flows, this report presents hydrologic, sediment, and nutrient budgets for Old Gillespie Lake and New Gillespie Lake, calculated by the U.S. Geological Survey with data collected during May 1996-April 1997 in cooperation with the Illinois Environmental Protection Agency and the city of Gillespie, Illinois. Bathymetric data also were collected in the two lakes to produce maps of the lake bed elevations. The influx of sediment, phosphorus, and nitrogen into Old Gillespie Lake during the study period was 4,063, 6.02, and 52.3 tons, respectively. Old Gillespie Lake retained 92 percent of the inflowing sediment (which agrees with theoretical calculations of trapping efficiency for Old Gillespie Lake), 84 percent of the inflowing phosphorus, and 87 percent of the inflowing nitrogen. The influx of sediment, phosphorus, and nitrogen into New Gillespie Lake during the study period was 4,792, 7.56, and 64.3 tons, respectively. Old Gillespie Lake retained 95 percent of the inflowing sediment (which agrees with theoretical calculations of trapping efficiency for New Gillespie Lake), 82 percent of the inflowing phosphorus, and 81 percent of the inflowing nitrogen. The loads per area of phosphorus and nitrogen to the Gillespie Lakes were 1.06 tons/mi2 and 9.26 tons/mi2, respectively. For row crops of corn and soybeans, the literature reports ranges of loads per area of phosphorus of 0.15 to 1.43 tons/mi2 and of nitrogen of 0.86 to 11.43 tons/mi2. Therefore, loads to the Gillespie Lakes are relatively high for the given cropping practices, and application of best management practices may substantially reduce the per area loads of these nutrients. Considering these loads and retention of sediment and nutrients, a

Localized-magnon states in strongly frustrated quantum spin lattices

International Nuclear Information System (INIS)

Richter, J.

2005-01-01

Recent developments concerning localized-magnon eigenstates in strongly frustrated spin lattices and their effect on the low-temperature physics of these systems in high magnetic fields are reviewed. After illustrating the construction and the properties of localized-magnon states we describe the plateau and the jump in the magnetization process caused by these states. Considering appropriate lattice deformations fitting to the localized magnons we discuss a spin-Peierls instability in high magnetic fields related to these states. Last but not least we consider the degeneracy of the localized-magnon eigenstates and the related thermodynamics in high magnetic fields. In particular, we discuss the low-temperature maximum in the isothermal entropy versus field curve and the resulting enhanced magnetocaloric effect, which allows efficient magnetic cooling from quite large temperatures down to very low ones

Local Foods, Local Places Summary Reports

Science.gov (United States)

These reports summarize community projects done with Local Foods, Local Places assistance, including farmers markets, cooperatives, community gardens, and other food-related enterprises that can boost local economies and drive revitalization.

Geomorphological and petrological observations along a segment of slow-spreading Carlsberg Ridge

Digital Repository Service at National Institute of Oceanography (India)

Mudholkar, A.V.; Kodagali, V.N.; KameshRaju, K.A.; Valsangkar, A.B.; Ranade, G.; Ambre, N.V.

A 120-km-long section of the Carlsberg Ridge has been mapped with multi-beam bathymetry system (MBS). High-resolution bathymetric contour map generated with the MBS data shows well-defined axial valley bordered by steep valley walls and the presence...

High Resolution Vp and Vp/Vs Local Earthquake Tomography of the Val d'Agri Region (Southern Apennines, Italy).

Science.gov (United States)

Improta, L.; Bagh, S.; De Gori, P.; Pastori, M.; Piccinini, D.; Valoroso, L.; Anselmi, M.; Buttinelli, M.; Chiarabba, C.

2015-12-01

The Val d'Agri (VA) Quaternary basin in the southern Apennines extensional belt hosts the largest oilfield in onshore Europe and normal-fault systems with high (up to M7) seismogenic potential. Frequent small-magnitude swarms related to both active crustal extension and anthropogenic activity have occurred in the region. Causal factors for induced seismicity are a water impoundment with severe seasonal oscillations and a high-rate wastewater injection well. We analyzed around 1200 earthquakes (MLENI petroleum company. We used local earthquake tomography to investigate static and transient features of the crustal velocity structure and to accurately locate earthquakes. Vp and Vp/Vs models are parameterized by a 3x3x2 km spacing and well resolved down to about 12 km depth. The complex Vp model illuminates broad antiformal structures corresponding to wide ramp-anticlines involving Mesozoic carbonates of the Apulia hydrocarbon reservoir, and NW-SE trending low Vp regions related to thrust-sheet-top clastic basins. The VA basin corresponds to shallow low-Vp region. Focal mechanisms show normal faulting kinematics with minor strike slip solutions in agreement with the local extensional regime. Earthquake locations and focal solutions depict shallow (< 5 km depth) E-dipping extensional structures beneath the artificial lake located in the southern sector of the basin, and along the western margin of the VA. A few swarms define relatively deep transfer structures accommodating the differential extension between main normal faults. The spatio-temporal distribution of around 220 events correlates with wastewater disposal activity, illuminating a NE-dipping fault between 2-5 km depth in the carbonate reservoir. The fault measures 5 km along dip and corresponds to a pre-existing thrust fault favorably oriented with respect to the local extensional field.

Local visual perception bias in children with high-functioning autism spectrum disorders; do we have the whole picture?

Science.gov (United States)

Falkmer, Marita; Black, Melissa; Tang, Julia; Fitzgerald, Patrick; Girdler, Sonya; Leung, Denise; Ordqvist, Anna; Tan, Tele; Jahan, Ishrat; Falkmer, Torbjorn

2016-01-01

While local bias in visual processing in children with autism spectrum disorders (ASD) has been reported to result in difficulties in recognizing faces and facially expressed emotions, but superior ability in disembedding figures, associations between these abilities within a group of children with and without ASD have not been explored. Possible associations in performance on the Visual Perception Skills Figure-Ground test, a face recognition test and an emotion recognition test were investigated within 25 8-12-years-old children with high-functioning autism/Asperger syndrome, and in comparison to 33 typically developing children. Analyses indicated a weak positive correlation between accuracy in Figure-Ground recognition and emotion recognition. No other correlation estimates were significant. These findings challenge both the enhanced perceptual function hypothesis and the weak central coherence hypothesis, and accentuate the importance of further scrutinizing the existance and nature of local visual bias in ASD.

Mathematical programming solver based on local search

CERN Document Server

Gardi, Frédéric; Darlay, Julien; Estellon, Bertrand; Megel, Romain

2014-01-01

This book covers local search for combinatorial optimization and its extension to mixed-variable optimization. Although not yet understood from the theoretical point of view, local search is the paradigm of choice for tackling large-scale real-life optimization problems. Today's end-users demand interactivity with decision support systems. For optimization software, this means obtaining good-quality solutions quickly. Fast iterative improvement methods, like local search, are suited to satisfying such needs. Here the authors show local search in a new light, in particular presenting a new kind of mathematical programming solver, namely LocalSolver, based on neighborhood search. First, an iconoclast methodology is presented to design and engineer local search algorithms. The authors' concern about industrializing local search approaches is of particular interest for practitioners. This methodology is applied to solve two industrial problems with high economic stakes. Software based on local search induces ex...

Highly sensitive nano-porous lattice biosensor based on localized surface plasmon resonance and interference.

Science.gov (United States)

Yeom, Se-Hyuk; Kim, Ok-Geun; Kang, Byoung-Ho; Kim, Kyu-Jin; Yuan, Heng; Kwon, Dae-Hyuk; Kim, Hak-Rin; Kang, Shin-Won

2011-11-07

We propose a design for a highly sensitive biosensor based on nanostructured anodized aluminum oxide (AAO) substrates. A gold-deposited AAO substrate exhibits both optical interference and localized surface plasmon resonance (LSPR). In our sensor, application of these disparate optical properties overcomes problems of limited sensitivity, selectivity, and dynamic range seen in similar biosensors. We fabricated uniform periodic nanopore lattice AAO templates by two-step anodizing and assessed their suitability for application in biosensors by characterizing the change in optical response on addition of biomolecules to the AAO template. To determine the suitability of such structures for biosensing applications, we immobilized a layer of C-reactive protein (CRP) antibody on a gold coating atop an AAO template. We then applied a CRP antigen (Ag) atop the immobilized antibody (Ab) layer. The shift in reflectance is interpreted as being caused by the change in refractive index with membrane thickness. Our results confirm that our proposed AAO-based biosensor is highly selective toward detection of CRP antigen, and can measure a change in CRP antigen concentration of 1 fg/ml. This method can provide a simple, fast, and sensitive analysis for protein detection in real-time.

Split-Course, High-Dose Palliative Pelvic Radiotherapy for Locally Progressive Hormone-Refractory Prostate Cancer

Energy Technology Data Exchange (ETDEWEB)

Gogna, Nirdosh Kumar, E-mail: kumar_gogna@health.qld.gov.au [Radiation Oncology Services, Mater Centre, Brisbane, Queensland (Australia); Baxi, Siddhartha; Hickey, Brigid; Baumann, Kathryn [Radiation Oncology Services, Mater Centre, Brisbane, Queensland (Australia); Burmeister, Elizabeth [Princess Alexandra Hospital, Brisbane, Queensland (Australia); Holt, Tanya [Radiation Oncology Services, Mater Centre, Brisbane, Queensland (Australia)

2012-06-01

Purpose: Local progression, in patients with hormone-refractory prostate cancer, often causes significant morbidity. Pelvic radiotherapy (RT) provides effective palliation in this setting, with most published studies supporting the use of high-dose regimens. The aim of the present study was to examine the role of split-course hypofractionated RT used at our institution in treating this group of patients. Methods and Materials: A total of 34 men with locoregionally progressive hormone-refractory prostate cancer, treated with a split course of pelvic RT (45-60 Gy in 18-24 fractions) between 2000 and 2008 were analyzed. The primary endpoints were the response rate and actuarial locoregional progression-free survival. Secondary endpoints included overall survival, compliance, and acute and late toxicity. Results: The median age was 71 years (range, 53-88). Treatment resulted in an overall initial response rate of 91%, a median locoregional progression-free survival of 43 months, and median overall survival of 28 months. Compliance was excellent and no significant late toxicity was reported. Conclusions: The split course pelvic RT described has an acceptable toxicity profile, is effective, and compares well with other high-dose palliative regimens that have been previously reported.

Criteria of assessment for local wall thickness reductions in operative high-pressure gas pipelines; Beurteilungskriterien fuer lokale Wanddickenminderungen an in Betrieb befindlichen Gashochdruckleitungen

Energy Technology Data Exchange (ETDEWEB)

Hass, Georg [NetzDienste Rhein/Main GmbH, Frankfurt am Main (Germany); Hoffman, Ulrich [VNG - Verbundnetz Gas AG, Leipzig (Germany); Konarske, Juergen [RWE Westfalen-Weser-Ems Netzservice GmbH, Recklinghausen (Germany); Soppa, Thorsten [NG Netz Gas+Wasser (Germany). Bau/Betrieb Hochdrucknetz; Steiner, Michael [Open Grid Europe GmbH, Essen (Germany). Integritaet/Werkstofftechnik

2011-07-01

TUeV Nord, Salzgitter Mannesmann Forschung and DVGW investigated methods to assess local wall thickness reductions in operative high-pressure gas pipelines. Methods described in the relevant literature were reviewed with regard to the limiting criteria defined for maximum permissible wall thickness reductions. On the basis of this literature study and additional calculations, a comparative evaluation of the available methods was made. Several methods were identified that are compatible with the existing safety concept and general availability. It was found that - nearly independent of the method - burst safeties of 1.8 to 2.0 were used. The ultimate goal is the development of a German standard evaluation concept for local wall thickness reductions in high-pressure gas pipelines in order to avoid uncertainties and/or misinterpretations.

Calculations with the quasirelativistic local-spin-density-functional theory for high-Z atoms

International Nuclear Information System (INIS)

Guo, Y.; Whitehead, M.A.

1988-01-01

The generalized-exchange local-spin-density-functional theory (LSD-GX) with relativistic corrections of the mass velocity and Darwin terms has been used to calculate statistical total energies for the neutral atoms, the positive ions, and the negative ions for high-Z elements. The effect of the correlation and relaxation correction on the statistical total energy is discussed. Comparing the calculated results for the ionization potentials and electron affinities for the atoms (atomic number Z from 37 to 56 and 72 to 80) with experiment, shows that for the atoms rubidium to barium both the LSD-GX and the quasirelativistic LSD-GX, with self-interaction correction, Gopinathan, Whitehead, and Bogdanovic's Fermi-hole parameters [Phys. Rev. A 14, 1 (1976)], and Vosko, Wilk, and Nusair's correlation correction [Can. J. Phys. 58, 1200 (1980)], are very good methods for calculating ionization potentials and electron affinities. For the atoms hafnium to mercury the relativistic effect has to be considered

Local density approach to surfaces and adsorbed layers

International Nuclear Information System (INIS)

Wimmer, E.; Freeman, A.J.; Weinert, M.

1986-01-01

The authors show that the local density problem for the thin film geometry can be solved with high accuracy by employing the all-electron full-potential linearized augmented-plane-wave method. This is achieved by removing all shape approximations in the charge density and the potential and by using a highly flexible variational basis set. Also demonstrated is the fact that for a graphite monolayer, local density total energies give excellent descriptions of equilibrium geometries and discuss the overestimation of local-density cohesive energies due to an incomplete treatment of correlation effects in the free atom

Combined high-intensity local treatment and systemic therapy in metastatic head and neck squamous cell carcinoma: An analysis of the National Cancer Data Base.

Science.gov (United States)

Zumsteg, Zachary S; Luu, Michael; Yoshida, Emi J; Kim, Sungjin; Tighiouart, Mourad; David, John M; Shiao, Stephen L; Mita, Alain C; Scher, Kevin S; Sherman, Eric J; Lee, Nancy Y; Ho, Allen S

2017-12-01

There is increasing evidence that primary tumor ablation can improve survival for some cancer patients with distant metastases. This may be particularly applicable to head and neck squamous cell carcinoma (HNSCC) because of its tropism for locoregional progression. This study included patients with metastatic HNSCC undergoing systemic therapy identified in the National Cancer Data Base. High-intensity local treatment was defined as radiation doses ≥ 60 Gy or oncologic resection of the primary tumor. Multivariate Cox regression, propensity score matching, landmark analysis, and subgroup analysis were performed to account for imbalances in covariates, including adjustments for the number and location of metastatic sites in the subset of patients with this information available. In all, 3269 patients were included (median follow-up, 51.5 months). Patients undergoing systemic therapy with local treatment had improved survival in comparison with patients receiving systemic therapy alone in propensity score-matched cohorts (2-year overall survival, 34.2% vs 20.6%; P treatment, whereas those receiving lower-intensity local treatment had survival similar to that of patients receiving systemic therapy without local treatment. The impact of high-intensity local therapy was time-dependent, with a stronger impact within the first 6 months after the diagnosis (adjusted hazard ratio [AHR], 0.255; 95% confidence interval [CI], 0.210-0.309; P treatment warrants prospective evaluation for select patients with metastatic HNSCC. Cancer 2017;123:4583-4593. © 2017 American Cancer Society. © 2017 American Cancer Society.

Localization of iron in rice grain using synchrotron X-ray fluorescence microscopy and high resolution secondary ion mass spectrometry

KAUST Repository

Kyriacou, Bianca; Moore, Katie L.; Paterson, David J.; De Jonge, Martin Daly; Howard, Daryl Lloyd; Stangoulis, James Constantine R; Tester, Mark A.; Lombi, E.; Johnson, Alexander A T

2014-01-01

Cereal crops accumulate low levels of iron (Fe) of which only a small fraction (5-10%) is bioavailable in human diets. Extensive co-localization of Fe in outer grain tissues with phytic acid, a strong chelator of metal ions, results in the formation of insoluble complexes that cannot be digested by humans. Here we describe the use of synchrotron X-ray fluorescence microscopy (XFM) and high resolution secondary ion mass spectrometry (NanoSIMS) to map the distribution of Fe, zinc (Zn), phosphorus (P) and other elements in the aleurone and subaleurone layers of mature grain from wild-type and an Fe-enriched line of rice (Oryza sativa L.). The results obtained from both XFM and NanoSIMS indicated that most Fe was co-localized with P (indicative of phytic acid) in the aleurone layer but that a small amount of Fe, often present as "hotspots", extended further into the subaleurone and outer endosperm in a pattern that was not co-localized with P. We hypothesize that Fe in subaleurone and outer endosperm layers of rice grain could be bound to low molecular weight chelators such as nicotianamine and/or deoxymugineic acid. © 2014.

Localization of iron in rice grain using synchrotron X-ray fluorescence microscopy and high resolution secondary ion mass spectrometry

KAUST Repository

Kyriacou, Bianca

2014-03-01

Cereal crops accumulate low levels of iron (Fe) of which only a small fraction (5-10%) is bioavailable in human diets. Extensive co-localization of Fe in outer grain tissues with phytic acid, a strong chelator of metal ions, results in the formation of insoluble complexes that cannot be digested by humans. Here we describe the use of synchrotron X-ray fluorescence microscopy (XFM) and high resolution secondary ion mass spectrometry (NanoSIMS) to map the distribution of Fe, zinc (Zn), phosphorus (P) and other elements in the aleurone and subaleurone layers of mature grain from wild-type and an Fe-enriched line of rice (Oryza sativa L.). The results obtained from both XFM and NanoSIMS indicated that most Fe was co-localized with P (indicative of phytic acid) in the aleurone layer but that a small amount of Fe, often present as "hotspots", extended further into the subaleurone and outer endosperm in a pattern that was not co-localized with P. We hypothesize that Fe in subaleurone and outer endosperm layers of rice grain could be bound to low molecular weight chelators such as nicotianamine and/or deoxymugineic acid. © 2014.

Classifications, definitions and concepts of locality in Africa.

Science.gov (United States)

1983-01-01

Sub-Saharan Africa, one of the world's least urbanized regions, has within the last 30 years or so been experiencing a very high rate of urban population growth. The prevalence of small localities, invariably spread out over large land surfaces, complicates the classifications and definitions of localities as well as making the identification of settlement patterns in a mapping exercise and during a census or survey field operation difficult. The distinguishing features of a locality are: 1) a distinct (separate) population cluster, 2) inhabitants live in neighboring quarters, and 3) it has a name or a locally recognized status. Even in African countries, where the definition of locality as a distinct population cluster has been employed, problems have cropped up with respect to classifications and identifications. Another problem with the classification of localities is related to the rapid changes that occur in rural settlement patterns. Despite the rapid growth of urban localities within the past few years in sub-Saharan Africa, the proportion of the population living in urban localities is still low. Whereas a locality is a distinct population cluster, with definable boundaries, the village as employed in some countries does not have clear cut boundaries. The definition of a locality as a distinct population cluster in which the inhabitants live in neighboring living quarters and which has a name or a locally recognized status is highly recommended. The UN proposal for the adoption of a classification scheme by size of locality needs to be examined by African countries. The urban/rural dichotomy is recommended for the classification of some tabulations from censuses and surveys--especially on the total population and population of major and minor civil divisions.

More about the comparison of local and non-local NN interaction models

International Nuclear Information System (INIS)

Amghar, A.; Desplanques, B.

2003-01-01

The effect of non-locality in the NN interaction with an off-energy shell character has been studied in the past in relation with the possibility that some models could be approximately phase-shifts equivalent. This work is extended to a non-locality implying terms that involve an anticommutator with the operator p 2 . It includes both scalar and tensor components. The most recent 'high accuracy' models are considered in the analysis. After studying the deuteron wave functions, electromagnetic properties of various models are compared with the idea that these ones differ by their non-locality but are equivalent up to a unitary transformation. It is found that the extra non-local tensor interaction considered in this work tends to re-enforce the role of the term considered in previous works, allowing one to explain almost completely the difference in the deuteron D-state probabilities evidenced by the comparison of the Bonn-QB and Paris models for instance. Conclusions for the effect of the non-local scalar interaction are not so clear. In many cases, it was found that these terms could explain part of the differences that the comparison of predictions for various models evidences but cases where they could not were also found. Some of these last ones have been analyzed in order to pointing out the origin of the failure

High and distinct range-edge genetic diversity despite local bottlenecks.

Directory of Open Access Journals (Sweden)

Jorge Assis

Full Text Available The genetic consequences of living on the edge of distributional ranges have been the subject of a largely unresolved debate. Populations occurring along persistent low latitude ranges (rear-edge are expected to retain high and unique genetic diversity. In contrast, currently less favourable environmental conditions limiting population size at such range-edges may have caused genetic erosion that prevails over past historical effects, with potential consequences on reducing future adaptive capacity. The present study provides an empirical test of whether population declines towards a peripheral range might be reflected on decreasing diversity and increasing population isolation and differentiation. We compare population genetic differentiation and diversity with trends in abundance along a latitudinal gradient towards the peripheral distribution range of Saccorhiza polyschides, a large brown seaweed that is the main structural species of kelp forests in SW Europe. Signatures of recent bottleneck events were also evaluated to determine whether the recently recorded distributional shifts had a negative influence on effective population size. Our findings show decreasing population density and increasing spatial fragmentation and local extinctions towards the southern edge. Genetic data revealed two well supported groups with a central contact zone. As predicted, higher differentiation and signs of bottlenecks were found at the southern edge region. However, a decrease in genetic diversity associated with this pattern was not verified. Surprisingly, genetic diversity increased towards the edge despite bottlenecks and much lower densities, suggesting that extinctions and recolonizations have not strongly reduced diversity or that diversity might have been even higher there in the past, a process of shifting genetic baselines.

High spatial correspondence at a columnar level between activation and resting state fMRI signals and local field potentials.

Science.gov (United States)

Shi, Zhaoyue; Wu, Ruiqi; Yang, Pai-Feng; Wang, Feng; Wu, Tung-Lin; Mishra, Arabinda; Chen, Li Min; Gore, John C

2017-05-16

Although blood oxygenation level-dependent (BOLD) fMRI has been widely used to map brain responses to external stimuli and to delineate functional circuits at rest, the extent to which BOLD signals correlate spatially with underlying neuronal activity, the spatial relationships between stimulus-evoked BOLD activations and local correlations of BOLD signals in a resting state, and whether these spatial relationships vary across functionally distinct cortical areas are not known. To address these critical questions, we directly compared the spatial extents of stimulated activations and the local profiles of intervoxel resting state correlations for both high-resolution BOLD at 9.4 T and local field potentials (LFPs), using 98-channel microelectrode arrays, in functionally distinct primary somatosensory areas 3b and 1 in nonhuman primates. Anatomic images of LFP and BOLD were coregistered within 0.10 mm accuracy. We found that the point spread functions (PSFs) of BOLD and LFP responses were comparable in the stimulus condition, and both estimates of activations were slightly more spatially constrained than local correlations at rest. The magnitudes of stimulus responses in area 3b were stronger than those in area 1 and extended in a medial to lateral direction. In addition, the reproducibility and stability of stimulus-evoked activation locations within and across both modalities were robust. Our work suggests that the intrinsic resolution of BOLD is not a limiting feature in practice and approaches the intrinsic precision achievable by multielectrode electrophysiology.

Atom-atom collision cascades localization

International Nuclear Information System (INIS)

Kirsanov, V.V.

1980-01-01

The presence of an impurity and thermal vibration influence on the atom-atom collision cascade development is analysed by the computer simulation method (the modificated dynamic model). It is discovered that the relatively low energetic cascades are localized with the temperature increase of an irradiated crystal. On the basis of the given effect the mechanism of splitting of the high energetic cascades into subcascades is proposed. It accounts for two factors: the primary knocked atom energy and the irradiated crystal temperature. Introduction of an impurity also localizes the cascades independently from the impurity atom mass. The cascades localization leads to intensification of the process of annealing in the cascades and reduction of the post-cascade vacancy cluster sizes. (author)

Exploring Localization in Nuclear Spin Chains

Science.gov (United States)

Wei, Ken Xuan; Ramanathan, Chandrasekhar; Cappellaro, Paola

2018-02-01

Characterizing out-of-equilibrium many-body dynamics is a complex but crucial task for quantum applications and understanding fundamental phenomena. A central question is the role of localization in quenching thermalization in many-body systems and whether such localization survives in the presence of interactions. Probing this question in real systems necessitates the development of an experimentally measurable metric that can distinguish between different types of localization. While it is known that the localized phase of interacting systems [many-body localization (MBL)] exhibits a long-time logarithmic growth in entanglement entropy that distinguishes it from the noninteracting case of Anderson localization (AL), entanglement entropy is difficult to measure experimentally. Here, we present a novel correlation metric, capable of distinguishing MBL from AL in high-temperature spin systems. We demonstrate the use of this metric to detect localization in a natural solid-state spin system using nuclear magnetic resonance (NMR). We engineer the natural Hamiltonian to controllably introduce disorder and interactions, and observe the emergence of localization. In particular, while our correlation metric saturates for AL, it slowly keeps increasing for MBL, demonstrating analogous features to entanglement entropy, as we show in simulations. Our results show that our NMR techniques, akin to measuring out-of-time correlations, are well suited for studying localization in spin systems.

Localized scleroderma: clinical spectrum and therapeutic update.

Science.gov (United States)

Careta, Mariana Figueiroa; Romiti, Ricardo

2015-01-01

Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma. In this review, we report the most important aspects and particularities in the treatment of patients diagnosed with localized scleroderma.

Localized scleroderma: clinical spectrum and therapeutic update*

Science.gov (United States)

Careta, Mariana Figueiroa; Romiti, Ricardo

2015-01-01

Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma. In this review, we report the most important aspects and particularities in the treatment of patients diagnosed with localized scleroderma. PMID:25672301

Assessing subaqueous mudslide hazard on the Mississippi River delta front, Part 2: Insights revealed through high-resolution geophysical surveying

Science.gov (United States)

Obelcz, J.; Xu, K.; Bentley, S. J.; Georgiou, I. Y.; Maloney, J. M.; Miner, M. D.; Hanegan, K.; Keller, G.

2014-12-01

The northern Gulf of Mexico, including the subaqueous Mississippi River delta front (MRDF), has been productive for oil and gas development since the early 1900s. In 1969 cyclic seafloor wave loading associated with the passage of Hurricane Camille triggered subaqueous mudflows across the MRDF, destroying several offshore oil platforms. This incident spurred geophysical and geotechnical studies of the MRDF, which found that the delta front is prone to mass failures on gentle gradients (gas production, and (3) the frequent passage of tropical cyclones. In June 2014, a geophysical pilot study was conducted 8 km southwest of Southwest Pass, the distributary that currently receives the largest fraction of Mississippi River sediment supply. The resultant dataset encompasses 216 km of subbottom Chirp seismic profiles and a 60 km2 grid of bathymetry and sidescan data. Preliminary interpretation of these data shows the survey area can be classified into four primary sedimentary facies: mudflow gullies, mudflow lobes, undisturbed prodelta, and undisturbed delta front. Subbottom profiles reveal extensive biogenic gas from 20 to about 80 m water depths on the delta front; sidescan data show a variety of bottleneck slides, mudflow gullies and mudflow noses. Previous studies have attempted to constrain the periodicity and magnitude of subaqueous mudslides on the MRDF. However, large age gaps and varied resolution between datasets result in ambiguity regarding the cause and magnitude of observed bathymetric changes. We present high-temporal resolution MRDF bathymetric variations from 2005 (post Hurricane Katrina), 2009 (relatively quiescent storm period), and 2014 (post 2011 Mississippi River flood). These data yield better magnitude and timing estimates of mass movements. This exercise represents a first step towards (1) assembling a comprehensive geologic dataset upon which future MRDF geohazard assessments can be founded, and (2) understanding the dynamics of a massive

Suppression of large edge-localized modes in high-confinement DIII-D plasmas with a stochastic magnetic boundary.

Science.gov (United States)

Evans, T E; Moyer, R A; Thomas, P R; Watkins, J G; Osborne, T H; Boedo, J A; Doyle, E J; Fenstermacher, M E; Finken, K H; Groebner, R J; Groth, M; Harris, J H; La Haye, R J; Lasnier, C J; Masuzaki, S; Ohyabu, N; Pretty, D G; Rhodes, T L; Reimerdes, H; Rudakov, D L; Schaffer, M J; Wang, G; Zeng, L

2004-06-11

A stochastic magnetic boundary, produced by an applied edge resonant magnetic perturbation, is used to suppress most large edge-localized modes (ELMs) in high confinement (H-mode) plasmas. The resulting H mode displays rapid, small oscillations with a bursty character modulated by a coherent 130 Hz envelope. The H mode transport barrier and core confinement are unaffected by the stochastic boundary, despite a threefold drop in the toroidal rotation. These results demonstrate that stochastic boundaries are compatible with H modes and may be attractive for ELM control in next-step fusion tokamaks.

Dosimetric comparison of axilla and groin radiotherapy techniques for high-risk and locally advanced skin cancer

International Nuclear Information System (INIS)

Mattes, Malcolm D.; Zhou, Ying; Berry, Sean L.; Barker, Christopher A.

2016-01-01

Radiation therapy targeting axilla and groin lymph nodes improves regional disease control in locally advanced and high-risk skin cancers. However, trials generally used conventional two-dimensional radiotherapy (2D-RT), contributing towards relatively high rates of side effects from treatment. The goal of this study is to determine if three-dimensional conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT), or volumetric-modulated arc therapy (VMAT) may improve radiation delivery to the target while avoiding organs at risk in the clinical context of skin cancer regional nodal irradiation. Twenty patients with locally advanced/high-risk skin cancers underwent computed tomography simulation. The relevant axilla or groin planning target volumes and organs at risk were delineated using standard definitions. Paired t-tests were used to compare the mean values of several dose-volumetric parameters for each of the 4 techniques. In the axilla, the largest improvement for 3D-CRT compared to 2D-RT was for homogeneity index (13.9 vs. 54.3), at the expense of higher lung V 20 (28.0% vs. 12.6%). In the groin, the largest improvements for 3D-CRT compared to 2D-RT were for anorectum D max (13.6 vs. 38.9 Gy), bowel D 200cc (7.3 vs. 23.1 Gy), femur D 50 (34.6 vs. 57.2 Gy), and genitalia D max (37.6 vs. 51.1 Gy). IMRT had further improvements compared to 3D-CRT for humerus D mean (16.9 vs. 22.4 Gy), brachial plexus D 5 (57.4 vs. 61.3 Gy), bladder D 5 (26.8 vs. 36.5 Gy), and femur D 50 (18.7 vs. 34.6 Gy). Fewer differences were observed between IMRT and VMAT. Compared to 2D-RT and 3D-CRT, IMRT and VMAT had dosimetric advantages in the treatment of nodal regions of skin cancer patients

Dosimetric comparison of axilla and groin radiotherapy techniques for high-risk and locally advanced skin cancer

Energy Technology Data Exchange (ETDEWEB)

Mattes, Malcolm D.; Zhou, Ying; Berry, Sean L.; Barker, Christopher A. [Memorial Sloan Kettering Cancer Center, New York (United States)

2016-06-15

Radiation therapy targeting axilla and groin lymph nodes improves regional disease control in locally advanced and high-risk skin cancers. However, trials generally used conventional two-dimensional radiotherapy (2D-RT), contributing towards relatively high rates of side effects from treatment. The goal of this study is to determine if three-dimensional conformal radiation therapy (3D-CRT), intensity-modulated radiation therapy (IMRT), or volumetric-modulated arc therapy (VMAT) may improve radiation delivery to the target while avoiding organs at risk in the clinical context of skin cancer regional nodal irradiation. Twenty patients with locally advanced/high-risk skin cancers underwent computed tomography simulation. The relevant axilla or groin planning target volumes and organs at risk were delineated using standard definitions. Paired t-tests were used to compare the mean values of several dose-volumetric parameters for each of the 4 techniques. In the axilla, the largest improvement for 3D-CRT compared to 2D-RT was for homogeneity index (13.9 vs. 54.3), at the expense of higher lung V{sub 20} (28.0% vs. 12.6%). In the groin, the largest improvements for 3D-CRT compared to 2D-RT were for anorectum D{sub max} (13.6 vs. 38.9 Gy), bowel D{sub 200cc} (7.3 vs. 23.1 Gy), femur D{sub 50} (34.6 vs. 57.2 Gy), and genitalia D{sub max} (37.6 vs. 51.1 Gy). IMRT had further improvements compared to 3D-CRT for humerus D{sub mean} (16.9 vs. 22.4 Gy), brachial plexus D{sub 5} (57.4 vs. 61.3 Gy), bladder D{sub 5} (26.8 vs. 36.5 Gy), and femur D{sub 50} (18.7 vs. 34.6 Gy). Fewer differences were observed between IMRT and VMAT. Compared to 2D-RT and 3D-CRT, IMRT and VMAT had dosimetric advantages in the treatment of nodal regions of skin cancer patients.

High precision wavefront control in point spread function engineering for single emitter localization

Science.gov (United States)

Siemons, M.; Hulleman, C. N.; Thorsen, R. Ø.; Smith, C. S.; Stallinga, S.

2018-04-01

Point Spread Function (PSF) engineering is used in single emitter localization to measure the emitter position in 3D and possibly other parameters such as the emission color or dipole orientation as well. Advanced PSF models such as spline fits to experimental PSFs or the vectorial PSF model can be used in the corresponding localization algorithms in order to model the intricate spot shape and deformations correctly. The complexity of the optical architecture and fit model makes PSF engineering approaches particularly sensitive to optical aberrations. Here, we present a calibration and alignment protocol for fluorescence microscopes equipped with a spatial light modulator (SLM) with the goal of establishing a wavefront error well below the diffraction limit for optimum application of complex engineered PSFs. We achieve high-precision wavefront control, to a level below 20 m$\\lambda$ wavefront aberration over a 30 minute time window after the calibration procedure, using a separate light path for calibrating the pixel-to-pixel variations of the SLM, and alignment of the SLM with respect to the optical axis and Fourier plane within 3 $\\mu$m ($x/y$) and 100 $\\mu$m ($z$) error. Aberrations are retrieved from a fit of the vectorial PSF model to a bead $z$-stack and compensated with a residual wavefront error comparable to the error of the SLM calibration step. This well-calibrated and corrected setup makes it possible to create complex `3D+$\\lambda$' PSFs that fit very well to the vectorial PSF model. Proof-of-principle bead experiments show precisions below 10~nm in $x$, $y$, and $\\lambda$, and below 20~nm in $z$ over an axial range of 1 $\\mu$m with 2000 signal photons and 12 background photons.

A CATALOG OF ULTRA-COMPACT HIGH VELOCITY CLOUDS FROM THE ALFALFA SURVEY: LOCAL GROUP GALAXY CANDIDATES?

International Nuclear Information System (INIS)

Adams, Elizabeth A. K.; Giovanelli, Riccardo; Haynes, Martha P.

2013-01-01

We present a catalog of 59 ultra-compact high velocity clouds (UCHVCs) extracted from the 40% complete ALFALFA HI-line survey. The ALFALFA UCHVCs have median flux densities of 1.34 Jy km s –1 , median angular diameters of 10', and median velocity widths of 23 km s –1 . We show that the full UCHVC population cannot easily be associated with known populations of high velocity clouds. Of the 59 clouds presented here, only 11 are also present in the compact cloud catalog extracted from the commensal GALFA-HI survey, demonstrating the utility of this separate dataset and analysis. Based on their sky distribution and observed properties, we infer that the ALFALFA UCHVCs are consistent with the hypothesis that they may be very low mass galaxies within the Local Volume. In that case, most of their baryons would be in the form of gas, and because of their low stellar content, they remain unidentified by extant optical surveys. At distances of ∼1 Mpc, the UCHVCs have neutral hydrogen (H I) masses of ∼10 5 -10 6 M ☉ , H I diameters of ∼2-3 kpc, and indicative dynamical masses within the H I extent of ∼10 7 -10 8 M ☉ , similar to the Local Group ultra-faint dwarf Leo T. The recent ALFALFA discovery of the star-forming, metal-poor, low mass galaxy Leo P demonstrates that this hypothesis is true in at least one case. In the case of the individual UCHVCs presented here, confirmation of their extragalactic nature will require further work, such as the identification of an optical counterpart to constrain their distance.

Transient localization in the kicked Rydberg atom

International Nuclear Information System (INIS)

Persson, Emil; Fuerthauer, S.; Burgdoerfer, J.; Wimberger, S.

2006-01-01

We investigate the long-time limit of quantum localization of the kicked Rydberg atom. The kicked Rydberg atom is shown to possess in addition to the quantum localization time τ L a second crossover time t D where quantum dynamics diverges from classical dynamics towards increased instability. The quantum localization is shown to vanish as either the strength of the kicks at fixed principal quantum number or the quantum number at fixed kick strength increases. The survival probability as a function of frequency in the transient localization regime τ L D is characterized by highly irregular, fractal-like fluctuations

High n ballooning modes in highly elongated tokamaks

International Nuclear Information System (INIS)

An, C.H.; Bateman, G.

1980-02-01

An analytic study of stability against high n ballooning modes in highly elongated axisymmetric plasmas is presented and compared with computational results. From the equation for the marginal pressure gradient, it is found that the local shear plays an important role on the stability of elongated and shifted plasma, and that high elongation deteriorates the stability by decreasing the stabilizing effects of field line bending and local shear. The net contribution of the local shear to stability decreases with elongation and shift for strongly ballooning modes (eigenfunctions strongly localized near the outer edge of the toroidal flux surfaces) but increases for interchange modes (eigenfunctions more uniform along the flux surfaces). The computational study of high n ballooning modes in a highly elongated plasma reveals that lowering the aspect ratio and broadening the pressure profile enhance the marginal beta for β/sub p/ less than unity but severely reduce the marginal beta for β/sub p/ larger than unity

Tier 3 batch system data locality via managed caches

Science.gov (United States)

Fischer, Max; Giffels, Manuel; Jung, Christopher; Kühn, Eileen; Quast, Günter

2015-05-01

Modern data processing increasingly relies on data locality for performance and scalability, whereas the common HEP approaches aim for uniform resource pools with minimal locality, recently even across site boundaries. To combine advantages of both, the High- Performance Data Analysis (HPDA) Tier 3 concept opportunistically establishes data locality via coordinated caches. In accordance with HEP Tier 3 activities, the design incorporates two major assumptions: First, only a fraction of data is accessed regularly and thus the deciding factor for overall throughput. Second, data access may fallback to non-local, making permanent local data availability an inefficient resource usage strategy. Based on this, the HPDA design generically extends available storage hierarchies into the batch system. Using the batch system itself for scheduling file locality, an array of independent caches on the worker nodes is dynamically populated with high-profile data. Cache state information is exposed to the batch system both for managing caches and scheduling jobs. As a result, users directly work with a regular, adequately sized storage system. However, their automated batch processes are presented with local replications of data whenever possible.

Localization of multilayer networks by optimized single-layer rewiring.

Science.gov (United States)

Jalan, Sarika; Pradhan, Priodyuti

2018-04-01

We study localization properties of principal eigenvectors (PEVs) of multilayer networks (MNs). Starting with a multilayer network corresponding to a delocalized PEV, we rewire the network edges using an optimization technique such that the PEV of the rewired multilayer network becomes more localized. The framework allows us to scrutinize structural and spectral properties of the networks at various localization points during the rewiring process. We show that rewiring only one layer is enough to attain a MN having a highly localized PEV. Our investigation reveals that a single edge rewiring of the optimized MN can lead to the complete delocalization of a highly localized PEV. This sensitivity in the localization behavior of PEVs is accompanied with the second largest eigenvalue lying very close to the largest one. This observation opens an avenue to gain a deeper insight into the origin of PEV localization of networks. Furthermore, analysis of multilayer networks constructed using real-world social and biological data shows that the localization properties of these real-world multilayer networks are in good agreement with the simulation results for the model multilayer network. This paper is relevant to applications that require understanding propagation of perturbation in multilayer networks.

Structures of Xishan village landslide in Li County, Sichuan, China, inferred from high-frequency receiver functions of local earthquakes

Science.gov (United States)

Wei, Z.; Chu, R.

2017-12-01

Teleseismic receiver function methods are widely used to study the deep structural information beneath the seismic station. However, teleseismic waveforms are difficult to extract the high-frequency receiver function, which are insufficient to constrain the shallow structure because of the inelastic attenuation effect of the earth. In this study, using the local earthquake waveforms collected from 3 broadband stations deployed on the Xishan village landslide in Li County in Sichuan Province, we used the high-frequency receiver function method to study the shallow structure beneath the landslide. We developed the Vp-k (Vp/Vs) staking method of receiver functions, and combined with the H-k stacking and waveform inversion methods of receiver functions to invert the landslide's thickness, S-wave velocity and average Vp/Vs ratio beneath these stations, and compared the thickness with the borehole results. Our results show small-scale lateral variety of velocity structure, a 78-143m/s lower S-wave velocity in the bottom layer and 2.4-3.1 Vp/Vs ratio in the landslide. The observed high Vp/Vs ratio and low S-wave velocity in the bottom layer of the landslide are consistent with low electrical resistivity and water-rich in the bottom layer, suggesting a weak shear strength and potential danger zone in landslide h1. Our study suggest that the local earthquake receiver function can obtain the shallow velocity structural information and supply some seismic constrains for the landslide catastrophe mitigation.

High energy ion hit technique to local area using microbeam

Energy Technology Data Exchange (ETDEWEB)

Tanaka, Ryuichi; Kamiya, Tomihiro; Suda, Tamotsu; Sakai, Takuro; Hirao, Toshio; Kobayashi, Yasuhiko; Watanabe, Hiroshi [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

1997-03-01

Single energetic ion hit technique has been developed as an application of ion microbeam technique, in order to study the effect of local damage or injury to materials and living organisms. The overall performance is basically defined by those of separate techniques: microbeam formation, microbeam positioning, single ion detection, detection signal processing, hit timing control, and hit verification. Recent progress on the developments of these techniques at JAERI-TIARA facility are reviewed. (author)

Interbasin flow revisited: The contribution of local recharge to high-discharge springs, Death Valley, CA

Science.gov (United States)

Anderson, Katherine; Nelson, Stephen; Mayo, Alan; Tingey, David

2006-05-01

Springs in the Furnace Creek area (Texas, Travertine, and Nevares Springs) of Death Valley National Park exhibit high discharge rates and depleted δ18O VSMOW (˜-13‰) and δD VSMOW (˜-102‰) values. Isotopic depletion of this magnitude and large spring fluxes (˜10,000 L/min) suggests that modern local recharge in the arid Furnace Creek drainage cannot be responsible for spring fluxes. An alternate explanation, interbasin flow, is difficult to envisage due to the stratigraphic and structural relationships of bedrock in intervening ranges, although it is the most common conceptual model for Furnace Creek spring flows. High-flux springs at Furnace Creek nonetheless respond modestly to modern climate in terms of discharge rate and isotopic composition. Hydrographs show a climate response and variations in time-series stable isotope data of widely spaced springs track one another. Small, but measurable quantities of tritium (water for these springs may be, there appears to be a subtle, but recent climatic influence. Estimates of flow at nearby mountain springs produce discharge rates per square kilometer of catchment that, by analogy, could support from 20 to 300% of the flow at large Death Valley springs under the current climate. Yet, 14C model ages suggest valley-bottom springs at Furnace Creek (5500-14,500 yr) contain a large component of older water, suggesting that much of the water was recharged during a pluvial period (Younger Dryas?) when net infiltration would have been much higher and isotopically depleted. 14C model ages are also of similar age, or younger, than many 'up gradient' waters, rather than being older as would be expected for interbasin flow. Chemical evolution models of solutes are consistent with both local recharge and interbasin transfer from Ash Meadows. However, when considered with isotopic constraints, interbasin flow becomes obviously untenable. Estimates of the thickness of alluvium and semi-consolidated Tertiary units in the

Response of pancreatic cancer to local irradiation with high-energy neutrons

Energy Technology Data Exchange (ETDEWEB)

Cohen, Lionel; Woodruff, Katherine H.; Hendrickson, Frank R.; Kurup, Parvathy D.; Mansell, Joanne; Awschalom, Miguel; Rosenberg, Ivan; Ten Haken, Randall K.

1985-09-15

Seventy-seven patients with locally advanced, nonresectable, biopsy-proven adenocarcinoma of the pancreas were treated by palliative bypass surgery followed by intensive neutron beam irradiation of the primary tumor site. Three dose levels, under 20, 21 to 23, and 24 to 25 Gy, were studied with the use of a treatment plan that included all known disease within a limited target volume, generally under 21. Symptomatic palliation was achieved in the majority of patients. The median survival time was 6 months. One patient remained alive and well without evidence of tumor 5 years after irradiation. Two were free of tumor at autopsy (one had died of intercurrent disease and one of radiation-related complications). A common cause of death was metastatic dissemination. Complication rates were dosedependent; life-threatening complications did not exceed 12% with doses of less than 23 Gy. Autopsies from 19 patients were reviewed. In all, the pancreatic tumor site showed extensive reactive fibrosis. Local control was achieved in two patients, but most had both residual tumor in the pancreas and metastases. Six patients had centrolobular veno-occlusive liver disease. These patients had all received the higher (22–24 Gy) neutron doses. Six patients had hemorrhagic radiation gastroenteritis. Mild skin atrophy and bone marrow hypoplasia were seen in the irradiated volumes. The kidneys and spinal cord showed no radiation effects. The authors conclude that neutron irradiation can provide a good local response with marked regression and fibrosis of the tumor. This response, coupled with many deaths due to metastases, suggests that combined treatment with neutrons and chemotherapy would be worth exploring.

Fundamental Dimensions and Essential Elements of Exemplary Local Extension Units

Science.gov (United States)

Terry, Bryan D.; Osborne, Edward

2015-01-01

Collaborative efforts between federal, state, and local government agencies enable local Extension units to deliver a high level of educational opportunities to local citizens. These units represent land-grant institutions by delivering non-formal education that aim to address local, regional, and state concerns. The purpose of this study was to…

Trends in Data Locality Abstractions for HPC Systems

KAUST Repository

Unat, Didem; Dubey, Anshu; Hoefler, Torsten; Shalf, John; Abraham, Mark; Bianco, Mauro; Chamberlain, Bradford L.; Cledat, Romain; Edwards, H. Carter; Finkel, Hal; Fuerlinger, Karl; Hannig, Frank; Jeannot, Emmanuel; Kamil, Amir; Keasler, Jeff; Kelly, Paul H J; Leung, Vitus; Ltaief, Hatem; Maruyama, Naoya; Newburn, Chris J.; Pericas, Miquel

2017-01-01

The cost of data movement has always been an important concern in high performance computing (HPC) systems. It has now become the dominant factor in terms of both energy consumption and performance. Support for expression of data locality has been explored in the past, but those efforts have had only modest success in being adopted in HPC applications for various reasons. them However, with the increasing complexity of the memory hierarchy and higher parallelism in emerging HPC systems, locality management has acquired a new urgency. Developers can no longer limit themselves to low-level solutions and ignore the potential for productivity and performance portability obtained by using locality abstractions. Fortunately, the trend emerging in recent literature on the topic alleviates many of the concerns that got in the way of their adoption by application developers. Data locality abstractions are available in the forms of libraries, data structures, languages and runtime systems; a common theme is increasing productivity without sacrificing performance. This paper examines these trends and identifies commonalities that can combine various locality concepts to develop a comprehensive approach to expressing and managing data locality on future large-scale high-performance computing systems.

Trends in Data Locality Abstractions for HPC Systems

KAUST Repository

Unat, Didem

2017-05-12

The cost of data movement has always been an important concern in high performance computing (HPC) systems. It has now become the dominant factor in terms of both energy consumption and performance. Support for expression of data locality has been explored in the past, but those efforts have had only modest success in being adopted in HPC applications for various reasons. them However, with the increasing complexity of the memory hierarchy and higher parallelism in emerging HPC systems, locality management has acquired a new urgency. Developers can no longer limit themselves to low-level solutions and ignore the potential for productivity and performance portability obtained by using locality abstractions. Fortunately, the trend emerging in recent literature on the topic alleviates many of the concerns that got in the way of their adoption by application developers. Data locality abstractions are available in the forms of libraries, data structures, languages and runtime systems; a common theme is increasing productivity without sacrificing performance. This paper examines these trends and identifies commonalities that can combine various locality concepts to develop a comprehensive approach to expressing and managing data locality on future large-scale high-performance computing systems.

Performance Assessment of High Resolution Airborne Full Waveform LiDAR for Shallow River Bathymetry

Directory of Open Access Journals (Sweden)

Zhigang Pan

2015-04-01

Full Text Available We evaluate the performance of full waveform LiDAR decomposition algorithms with a high-resolution single band airborne LiDAR bathymetry system in shallow rivers. A continuous wavelet transformation (CWT is proposed and applied in two fluvial environments, and the results are compared to existing echo retrieval methods. LiDAR water depths are also compared to independent field measurements. In both clear and turbid water, the CWT algorithm outperforms the other methods if only green LiDAR observations are available. However, both the definition of the water surface, and the turbidity of the water significantly influence the performance of the LiDAR bathymetry observations. The results suggest that there is no single best full waveform processing algorithm for all bathymetric situations. Overall, the optimal processing strategies resulted in a determination of water depths with a 6 cm mean at 14 cm standard deviation for clear water, and a 16 cm mean and 27 cm standard deviation in more turbid water.

Face Alignment via Regressing Local Binary Features.

Science.gov (United States)

Ren, Shaoqing; Cao, Xudong; Wei, Yichen; Sun, Jian

2016-03-01

This paper presents a highly efficient and accurate regression approach for face alignment. Our approach has two novel components: 1) a set of local binary features and 2) a locality principle for learning those features. The locality principle guides us to learn a set of highly discriminative local binary features for each facial landmark independently. The obtained local binary features are used to jointly learn a linear regression for the final output. This approach achieves the state-of-the-art results when tested on the most challenging benchmarks to date. Furthermore, because extracting and regressing local binary features are computationally very cheap, our system is much faster than previous methods. It achieves over 3000 frames per second (FPS) on a desktop or 300 FPS on a mobile phone for locating a few dozens of landmarks. We also study a key issue that is important but has received little attention in the previous research, which is the face detector used to initialize alignment. We investigate several face detectors and perform quantitative evaluation on how they affect alignment accuracy. We find that an alignment friendly detector can further greatly boost the accuracy of our alignment method, reducing the error up to 16% relatively. To facilitate practical usage of face detection/alignment methods, we also propose a convenient metric to measure how good a detector is for alignment initialization.

High RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma

International Nuclear Information System (INIS)

Téllez-Gabriel, Marta; Arroyo-Solera, Irene; León, Xavier; Gallardo, Alberto; López, Montserrat; Céspedes, Maria V; Casanova, Isolda; López-Pousa, Antonio; Quer, Miquel; Mangues, Maria A; Barnadas, Agustí; Mangues, Ramón; Pavón, Miguel A

2013-01-01

Currently there are no molecular markers able to predict clinical outcome in locally advanced head and neck squamous cell carcinoma (HNSCC). In a previous microarray study, RAB25 was identified as a potential prognostic marker. The aim of this study was to analyze the association between RAB25 expression and clinical outcome in patients with locally advanced HNSCC treated with standard therapy. In a retrospective immunohistochemical study (n = 97), we observed that RAB25-negative tumors had lower survival (log-rank, P = 0.01) than patients bearing positive tumors. In an independent prospective mRNA study (n = 117), low RAB25 mRNA expression was associated with poor prognosis. Using classification and regression tree analysis (CART) we established two groups of patients according to their RAB25 mRNA level and their risk of death. Low mRNA level was associated with poor local recurrence-free (log-rank, P = 0.005), progression-free (log-rank, P = 0.002) and cancer-specific (log-rank, P < 0.001) survival. Multivariate Cox model analysis showed that low expression of RAB25 was an independent poor prognostic factor for survival (hazard ratio: 3.84, 95% confidence interval: 1.93–7.62, P < 0.001). Patients whose tumors showed high RAB25 expression had a low probability of death after treatment. We also found lower RAB25 expression in tumors than in normal tissue (Mann–Whitney U, P < 0.001). Moreover, overexpression of RAB25 in the UM-SCC-74B HNSCC cell line increased cisplatin sensitivity, and reduced cell migration and invasion. Our findings support a tumor suppressor role for RAB25 in HNSCC and its potential use to identify locally advanced patients with a high probability of survival after genotoxic treatment

Cost-Effective Class-Imbalance Aware CNN for Vehicle Localization and Categorization in High Resolution Aerial Images

Directory of Open Access Journals (Sweden)

Feimo Li

2017-05-01

Full Text Available Joint vehicle localization and categorization in high resolution aerial images can provide useful information for applications such as traffic flow structure analysis. To maintain sufficient features to recognize small-scaled vehicles, a regions with convolutional neural network features (R-CNN -like detection structure is employed. In this setting, cascaded localization error can be averted by equally treating the negatives and differently typed positives as a multi-class classification task, but the problem of class-imbalance remains. To address this issue, a cost-effective network extension scheme is proposed. In it, the correlated convolution and connection costs during extension are reduced by feature map selection and bi-partite main-side network construction, which are realized with the assistance of a novel feature map class-importance measurement and a new class-imbalance sensitive main-side loss function. By using an image classification dataset established from a set of traditional real-colored aerial images with 0.13 m ground sampling distance which are taken from the height of 1000 m by an imaging system composed of non-metric cameras, the effectiveness of the proposed network extension is verified by comparing with its similarly shaped strong counter-parts. Experiments show an equivalent or better performance, while requiring the least parameter and memory overheads are required.

Quantum localization of the kicked rydberg atom

Science.gov (United States)

Yoshida; Reinhold; Burgdorfer

2000-03-20

We investigate the quantum localization of the one-dimensional Rydberg atom subject to a unidirectional periodic train of impulses. For high frequencies of the train the classical system becomes chaotic and leads to fast ionization. By contrast, the quantum system is found to be remarkably stable. We find this quantum localization to be directly related to the existence of "scars" of the unstable periodic orbits of the system. The localization length is given by the energy excursion along the periodic orbits.

Japan's nuclear PA activity in local governments

International Nuclear Information System (INIS)

Fujii, Nobuyuki

1995-01-01

This presentation emphasises some points of PA activities, based on the experience of 'cooperation projects for local governments'. Local governments distribute the public information directly to the residents. This is very important because officers of the local government can be the opinion leaders of the region. Local government exist very close to the residents, while the central government is a distant and faceless existence for the local people. It is believed that the local governments play an imperative role in PA activities. In other words, we must further utilize the organizations and functions of the local governments to implement PA activities. In conclusion, three recommendations are offered. Firstly, enough budget and authority should be given to the local governments as far as PA activities in their areas are concerned, and most of such activities should be entrusted to the local governments. Local governments should place more public relations officers, and continue the manpower development. Second, with regard to highly technical or specialized issues which a local governments cannot treat alone, related organizations like JAERO should support their PA activities. Third, such related organizations should also cooperate with local government including assistance in providing know-how, when their public information activities focus on educators, journalists, or the women. These three points should be given due consideration in our cooperation projects for the local governments, and JAERO is doing its best every day

HELAS: local helioseismology data website

International Nuclear Information System (INIS)

Schunker, Hannah; Gizon, Laurent; Roth, Markus

2008-01-01

The Local Helioseismology Network Activity is part of the European Helio-and Asteroseismology Network (HELAS). One aspect of the network activity is to collate multipurpose data sets and make them available to the community for local helioseismic analysis. The first stage of the project is underway whereby high quality and useful data sets have been selected and acquired. The HELAS Local Helioseismology Network Activity website at http://www.mps.mpg.de/projects/seismo/NA4/ provides this data ready to download. Furthermore, the data is supplemented with relevant documentation necessary for further analysis, including details about the data reduction process that has already been applied. The data primarily consists of Doppler velocity observations but also includes observations of the line-of-sight magnetic field, vector magnetic field measurements, intensity and travel time maps. The website will be continuously updated with data thereby providing convenient access to comprehensive data sets appropriate for use in local helioseismology.

Effects of riparian vegetation development in a restored lowland stream

NARCIS (Netherlands)

Vargas-Luna, A.; Crosato, A.; Hoitink, A.J.F.; Groot, J.; Uijttewaal, W.S.J.

2016-01-01

This paper presents the morphodynamic effects of riparian vegetation growth in a lowland restored stream. Hydrological series, high-resolution bathymetric data and aerial photographs are combined in the study. The vegetation root system was found to assert a strong control on soil stabilization,

In-core failure of the instrumented BWR rod by locally induced high coolant temperature

International Nuclear Information System (INIS)

Yanagisawa, Kazuaki

1985-12-01

In the BWR type light water loop instrumented in HBWR, a current BWR type fuel rod pre-irradiated up to 5.6 MWd/kgU was power ramped to 50 kW/m. During the ramp, the diameter of the rod was expanded significantly at the bottom end. The behaviour was different from which caused by pellet-cladding interaction (PCI). In the post-irradiation examination, the rod was found to be failed. In this paper, the cause of the failure was studied and obtained the followings. (1) The significant expansion of the rod diameter was attributed to marked oxidation of cladding outer diameter, appeared in the direction of 0 0 -180 0 degree with a shape of nodular. (2) The cladding in the place was softened by high coolant temperature. Coolant pressure, 7MPa intruded the cladding into inside chamfer void at pellet interface. (3) At the place of the significant oxidation, an instrumented transformer was existed and the coolant flow area was very little. The reduction of the coolant flow was enhanced by the bending of the cladding which was caused in pre-irradiation stage. They are considered to be a principal cause of local closure of coolant flow and resultant high temperature in the place. (author)

TreeMAC: Localized TDMA MAC protocol for real-time high-data-rate sensor networks

Science.gov (United States)

Song, W.-Z.; Huang, R.; Shirazi, B.; Husent, R.L.

2009-01-01

Earlier sensor network MAC protocols focus on energy conservation in low-duty cycle applications, while some recent applications involve real-time high-data-rate signals. This motivates us to design an innovative localized TDMA MAC protocol to achieve high throughput and low congestion in data collection sensor networks, besides energy conservation. TreeMAC divides a time cycle into frames and frame into slots. Parent determines children's frame assigmnent based on their relative bandwidth demand, and each node calculates its own slot assignment based on its hop-count to the sink. This innovative 2-dimensional frame-slot assignment algorithm has the following nice theory properties. Firstly, given any node, at any time slot, there is at most one active sender in its neighborhood (includ ing itself). Secondly, the packet scheduling with TreelMAC is bufferless, which therefore minimizes the probability of network congestion. Thirdly, the data throughput to gateway is at least 1/3 of the optimum assuming reliable links. Our experiments on a 24 node test bed demonstrate that TreeMAC protocol significantly improves network throughput and energy efficiency, by comparing to the TinyOS's default CSMA MAC protocol and a recent TDMA MAC protocol Funneling-MAC[8]. ?? 2009 IEEE.

High-Order Local Pooling and Encoding Gaussians Over a Dictionary of Gaussians.

Science.gov (United States)

Li, Peihua; Zeng, Hui; Wang, Qilong; Shiu, Simon C K; Zhang, Lei

2017-07-01

Local pooling (LP) in configuration (feature) space proposed by Boureau et al. explicitly restricts similar features to be aggregated, which can preserve as much discriminative information as possible. At the time it appeared, this method combined with sparse coding achieved competitive classification results with only a small dictionary. However, its performance lags far behind the state-of-the-art results as only the zero-order information is exploited. Inspired by the success of high-order statistical information in existing advanced feature coding or pooling methods, we make an attempt to address the limitation of LP. To this end, we present a novel method called high-order LP (HO-LP) to leverage the information higher than the zero-order one. Our idea is intuitively simple: we compute the first- and second-order statistics per configuration bin and model them as a Gaussian. Accordingly, we employ a collection of Gaussians as visual words to represent the universal probability distribution of features from all classes. Our problem is naturally formulated as encoding Gaussians over a dictionary of Gaussians as visual words. This problem, however, is challenging since the space of Gaussians is not a Euclidean space but forms a Riemannian manifold. We address this challenge by mapping Gaussians into the Euclidean space, which enables us to perform coding with common Euclidean operations rather than complex and often expensive Riemannian operations. Our HO-LP preserves the advantages of the original LP: pooling only similar features and using a small dictionary. Meanwhile, it achieves very promising performance on standard benchmarks, with either conventional, hand-engineered features or deep learning-based features.

Use of Aerial high resolution visible imagery to produce large river bathymetry: a multi temporal and spatial study over the by-passed Upper Rhine

Science.gov (United States)

Béal, D.; Piégay, H.; Arnaud, F.; Rollet, A.; Schmitt, L.

2011-12-01

Aerial high resolution visible imagery allows producing large river bathymetry assuming that water depth is related to water colour (Beer-Bouguer-Lambert law). In this paper we aim at monitoring Rhine River geometry changes for a diachronic study as well as sediment transport after an artificial injection (25.000 m3 restoration operation). For that a consequent data base of ground measurements of river depth is used, built on 3 different sources: (i) differential GPS acquisitions, (ii) sounder data and (iii) lateral profiles realized by experts. Water depth is estimated using a multi linear regression over neo channels built on a principal component analysis over red, green and blue bands and previously cited depth data. The study site is a 12 km long reach of the by-passed section of the Rhine River that draws French and German border. This section has been heavily impacted by engineering works during the last two centuries: channelization since 1842 for navigation purposes and the construction of a 45 km long lateral canal and 4 consecutive hydroelectric power plants of since 1932. Several bathymetric models are produced based on 3 different spatial resolutions (6, 13 and 20 cm) and 5 acquisitions (January, March, April, August and October) since 2008. Objectives are to find the optimal spatial resolution and to characterize seasonal effects. Best performances according to the 13 cm resolution show a 18 cm accuracy when suspended matters impacted less water transparency. Discussions are oriented to the monitoring of the artificial reload after 2 flood events during winter 2010-2011. Bathymetric models produced are also useful to build 2D hydraulic model's mesh.

Local contrast-enhanced MR images via high dynamic range processing.

Science.gov (United States)

Chandra, Shekhar S; Engstrom, Craig; Fripp, Jurgen; Neubert, Ales; Jin, Jin; Walker, Duncan; Salvado, Olivier; Ho, Charles; Crozier, Stuart

2018-09-01

To develop a local contrast-enhancing and feature-preserving high dynamic range (HDR) image processing algorithm for multichannel and multisequence MR images of multiple body regions and tissues, and to evaluate its performance for structure visualization, bias field (correction) mitigation, and automated tissue segmentation. A multiscale-shape and detail-enhancement HDR-MRI algorithm is applied to data sets of multichannel and multisequence MR images of the brain, knee, breast, and hip. In multisequence 3T hip images, agreement between automatic cartilage segmentations and corresponding synthesized HDR-MRI series were computed for mean voxel overlap established from manual segmentations for a series of cases. Qualitative comparisons between the developed HDR-MRI and standard synthesis methods were performed on multichannel 7T brain and knee data, and multisequence 3T breast and knee data. The synthesized HDR-MRI series provided excellent enhancement of fine-scale structure from multiple scales and contrasts, while substantially reducing bias field effects in 7T brain gradient echo, T 1 and T 2 breast images and 7T knee multichannel images. Evaluation of the HDR-MRI approach on 3T hip multisequence images showed superior outcomes for automatic cartilage segmentations with respect to manual segmentation, particularly around regions with hyperintense synovial fluid, across a set of 3D sequences. The successful combination of multichannel/sequence MR images into a single-fused HDR-MR image format provided consolidated visualization of tissues within 1 omnibus image, enhanced definition of thin, complex anatomical structures in the presence of variable or hyperintense signals, and improved tissue (cartilage) segmentation outcomes. © 2018 International Society for Magnetic Resonance in Medicine.

The Power Behind the Controversy: Understanding Local Policy Elites' Perceptions on the Benefits and Risks Associated with High Voltage Power Line Installation in the State of Arkansas

Science.gov (United States)

Moyer, Rachael M.

Following a proposal for the installation of high voltage power lines in northwest Arkansas, a controversial policy debate emerged. Proponents of the transmission line argue that such an installation is inevitable and necessary to efficiently and reliably support the identified electric load in the region. Opponents claim that the lines will degrade the natural environment and hamper the tourism-based local economy in affected regions, notably in Ozark Mountain areas. This study seeks to understand how local policy elites perceive the benefits and risks associated with proposed transmission lines, which is a critical step in comprehending the formation and changes of related government policies. First, based upon the dual process theory of judgment, this study systematically investigates the triadic relationships between (a) more profound personal value predispositions, (b) affects and feelings, and (c) perceived benefits and risks related to the proposed installation of high voltage power lines among local policy elites in the state of Arkansas. Next, this study focuses more specifically on the role of value predispositions, specific emotional dimensions of affect heuristics, and perceptions pertaining to high voltage power line risks and benefits. Using original data collected from a statewide Internet survey of 420 local leaders and key policymakers about their opinions on the related issues, other factors claimed by previous literature, including trust, knowledge level, and demographic characteristics are considered. Analytical results suggest that grid-group cultural predispositions, as deeply held core values within local policy elites' individual belief systems, both directly and indirectly -- through affective feelings -- shape perceived utility associated with the installation of high voltage power lines. Recognizing that risk perceptions factor into policy decisions, some practical considerations for better designing policy addressing controversial issues

A CATALOG OF ULTRA-COMPACT HIGH VELOCITY CLOUDS FROM THE ALFALFA SURVEY: LOCAL GROUP GALAXY CANDIDATES?

Energy Technology Data Exchange (ETDEWEB)

Adams, Elizabeth A. K.; Giovanelli, Riccardo; Haynes, Martha P., E-mail: betsey@astro.cornell.edu, E-mail: riccardo@astro.cornell.edu, E-mail: haynes@astro.cornell.edu [Center for Radiophysics and Space Research, Space Sciences Building, Cornell University, Ithaca, NY 14853 (United States)

2013-05-01

We present a catalog of 59 ultra-compact high velocity clouds (UCHVCs) extracted from the 40% complete ALFALFA HI-line survey. The ALFALFA UCHVCs have median flux densities of 1.34 Jy km s{sup -1}, median angular diameters of 10', and median velocity widths of 23 km s{sup -1}. We show that the full UCHVC population cannot easily be associated with known populations of high velocity clouds. Of the 59 clouds presented here, only 11 are also present in the compact cloud catalog extracted from the commensal GALFA-HI survey, demonstrating the utility of this separate dataset and analysis. Based on their sky distribution and observed properties, we infer that the ALFALFA UCHVCs are consistent with the hypothesis that they may be very low mass galaxies within the Local Volume. In that case, most of their baryons would be in the form of gas, and because of their low stellar content, they remain unidentified by extant optical surveys. At distances of {approx}1 Mpc, the UCHVCs have neutral hydrogen (H I) masses of {approx}10{sup 5}-10{sup 6} M{sub Sun }, H I diameters of {approx}2-3 kpc, and indicative dynamical masses within the H I extent of {approx}10{sup 7}-10{sup 8} M{sub Sun }, similar to the Local Group ultra-faint dwarf Leo T. The recent ALFALFA discovery of the star-forming, metal-poor, low mass galaxy Leo P demonstrates that this hypothesis is true in at least one case. In the case of the individual UCHVCs presented here, confirmation of their extragalactic nature will require further work, such as the identification of an optical counterpart to constrain their distance.

Bootstrapping realized volatility and realized beta under a local Gaussianity assumption

DEFF Research Database (Denmark)

Hounyo, Ulrich

The main contribution of this paper is to propose a new bootstrap method for statistics based on high frequency returns. The new method exploits the local Gaussianity and the local constancy of volatility of high frequency returns, two assumptions that can simplify inference in the high frequency...... context, as recently explained by Mykland and Zhang (2009). Our main contributions are as follows. First, we show that the local Gaussian bootstrap is firstorder consistent when used to estimate the distributions of realized volatility and ealized betas. Second, we show that the local Gaussian bootstrap...... matches accurately the first four cumulants of realized volatility, implying that this method provides third-order refinements. This is in contrast with the wild bootstrap of Gonçalves and Meddahi (2009), which is only second-order correct. Third, we show that the local Gaussian bootstrap is able...

Performance Analysis of Local Ensemble Kalman Filter

Science.gov (United States)

Tong, Xin T.

2018-03-01

Ensemble Kalman filter (EnKF) is an important data assimilation method for high-dimensional geophysical systems. Efficient implementation of EnKF in practice often involves the localization technique, which updates each component using only information within a local radius. This paper rigorously analyzes the local EnKF (LEnKF) for linear systems and shows that the filter error can be dominated by the ensemble covariance, as long as (1) the sample size exceeds the logarithmic of state dimension and a constant that depends only on the local radius; (2) the forecast covariance matrix admits a stable localized structure. In particular, this indicates that with small system and observation noises, the filter error will be accurate in long time even if the initialization is not. The analysis also reveals an intrinsic inconsistency caused by the localization technique, and a stable localized structure is necessary to control this inconsistency. While this structure is usually taken for granted for the operation of LEnKF, it can also be rigorously proved for linear systems with sparse local observations and weak local interactions. These theoretical results are also validated by numerical implementation of LEnKF on a simple stochastic turbulence in two dynamical regimes.

Affine-Invariant Geometric Constraints-Based High Accuracy Simultaneous Localization and Mapping

Directory of Open Access Journals (Sweden)

Gangchen Hua

2017-01-01

Full Text Available In this study we describe a new appearance-based loop-closure detection method for online incremental simultaneous localization and mapping (SLAM using affine-invariant-based geometric constraints. Unlike other pure bag-of-words-based approaches, our proposed method uses geometric constraints as a supplement to improve accuracy. By establishing an affine-invariant hypothesis, the proposed method excludes incorrect visual words and calculates the dispersion of correctly matched visual words to improve the accuracy of the likelihood calculation. In addition, camera’s intrinsic parameters and distortion coefficients are adequate for this method. 3D measuring is not necessary. We use the mechanism of Long-Term Memory and Working Memory (WM to manage the memory. Only a limited size of the WM is used for loop-closure detection; therefore the proposed method is suitable for large-scale real-time SLAM. We tested our method using the CityCenter and Lip6Indoor datasets. Our proposed method results can effectively correct the typical false-positive localization of previous methods, thus gaining better recall ratios and better precision.

How do electron localization functions describe π-electron delocalization?

Science.gov (United States)

Steinmann, Stephan N; Mo, Yirong; Corminboeuf, Clemence

2011-12-14

Scalar fields provide an intuitive picture of chemical bonding. In particular, the electron localization function (ELF) has proven to be highly valuable in interpreting a broad range of bonding patterns. The discrimination between enhanced or reduced electron (de)localization within cyclic π-conjugated systems remains, however, challenging for ELF. In order to clearly distinguish between the local properties of ten highly and weakly π-(de)localized prototype systems, we compare the ELFs of both the canonical wave functions and electron-localized states (diabatic) with those of two closely related scalar fields: the electron localizability indicator (ELI-D) and the localized orbital locator (LOL). The simplest LOL function distinguishes enhanced from weak π-(de)localization in an insightful and reliable manner. LOL offers the finest contrast between annulenes with 4n/4n + 2 π electrons and their inorganic analogues as well as between hyperconjugated cyclopentadiene derivatives. LOL(π) also gives an appealing and intuitive picture of the π-bond. In contrast, the most popular ELF fails to capture subtle contrasting local electronic properties and suffers from the arbitrariness of the σ/π dissection. The orbital separation of the most recent ELI-D is clear-cut but the interpretations sometime less straightforward in the present context.

A test for Improvement of high resolution Quantitative Precipitation Estimation for localized heavy precipitation events

Science.gov (United States)

Lee, Jung-Hoon; Roh, Joon-Woo; Park, Jeong-Gyun

2017-04-01

Accurate estimation of precipitation is one of the most difficult and significant tasks in the area of weather diagnostic and forecasting. In the Korean Peninsula, heavy precipitations are caused by various physical mechanisms, which are affected by shortwave trough, quasi-stationary moisture convergence zone among varying air masses, and a direct/indirect effect of tropical cyclone. In addition to, various geographical and topographical elements make production of temporal and spatial distribution of precipitation is very complicated. Especially, localized heavy rainfall events in South Korea generally arise from mesoscale convective systems embedded in these synoptic scale disturbances. In weather radar data with high temporal and spatial resolution, accurate estimation of rain rate from radar reflectivity data is too difficult. Z-R relationship (Marshal and Palmer 1948) have adapted representatively. In addition to, several methods such as support vector machine (SVM), neural network, Fuzzy logic, Kriging were utilized in order to improve the accuracy of rain rate. These methods show the different quantitative precipitation estimation (QPE) and the performances of accuracy are different for heavy precipitation cases. In this study, in order to improve the accuracy of QPE for localized heavy precipitation, ensemble method for Z-R relationship and various techniques was tested. This QPE ensemble method was developed by a concept based on utilizing each advantage of precipitation calibration methods. The ensemble members were produced for a combination of different Z-R coefficient and calibration method.

High-Dose-Rate Monotherapy for Localized Prostate Cancer: 10-Year Results

Energy Technology Data Exchange (ETDEWEB)

Hauswald, Henrik; Kamrava, Mitchell R.; Fallon, Julia M.; Wang, Pin-Chieh; Park, Sang-June; Van, Thanh; Borja, Lalaine; Steinberg, Michael L.; Demanes, D. Jeffrey, E-mail: JDemanes@mednet.ucla.edu

2016-03-15

Purpose: High-dose-rate (HDR) brachytherapy was originally used with external beam radiation therapy (EBRT) to increase the dose to the prostate without injuring the bladder or rectum. Numerous studies have reported HDR brachytherapy is safe and effective. We adapted it for use without EBRT for cases not requiring lymph node treatment. Patients and Methods: We entered the patient demographics, disease characteristics, and treatment parameters into a prospective registry and serially added follow-up data for 448 men with low-risk (n=288) and intermediate-risk (n=160) prostate cancer treated from 1996 to 2009. Their median age was 64 years (range 42-90). The median prostate-specific antigen (PSA) level was 6.0 ng/mL (range 0.2-18.2). The Gleason score was ≤6 in 76% and 7 in 24%. The median dose was 43.5 Gy in 6 fractions. The clinical and biochemical disease control and survival rates were calculated. Adverse events were graded according to the Common Toxicity Criteria of Adverse Events. Results: The median follow-up period was 6.5 years (range 0.3-15.3). The actuarial 6- and 10-year PSA progression-free survival was 98.6% (95% confidence interval [CI] 96.9%-99.4%) and 97.8% (95% CI 95.5%-98.9%). Overall survival at 10 years was 76.7% (95% CI 69.9%-82.2%). The local control, distant metastasis-free survival, and cause-specific survival were 99.7% (95% CI 97.9%-99.9%), 98.9% (95% CI 96.3%-99.7%), and 99.1% (95% CI 95.8%-99.8%). T stage, initial PSA level, Gleason score, National Comprehensive Cancer Network risk group, patient age, and androgen deprivation therapy did not significantly correlate with disease control or survival. No late grade 3 to 4 rectal toxicities developed. Late grade 3 to 4 genitourinary toxicity occurred in 4.9% (grade 3 in 4.7%). Conclusions: HDR monotherapy is a safe and highly effective treatment of low- and intermediate-risk prostate cancer.

A Least Square-Based Self-Adaptive Localization Method for Wireless Sensor Networks

Directory of Open Access Journals (Sweden)

Baoguo Yu

2016-01-01

Full Text Available In the wireless sensor network (WSN localization methods based on Received Signal Strength Indicator (RSSI, it is usually required to determine the parameters of the radio signal propagation model before estimating the distance between the anchor node and an unknown node with reference to their communication RSSI value. And finally we use a localization algorithm to estimate the location of the unknown node. However, this localization method, though high in localization accuracy, has weaknesses such as complex working procedure and poor system versatility. Concerning these defects, a self-adaptive WSN localization method based on least square is proposed, which uses the least square criterion to estimate the parameters of radio signal propagation model, which positively reduces the computation amount in the estimation process. The experimental results show that the proposed self-adaptive localization method outputs a high processing efficiency while satisfying the high localization accuracy requirement. Conclusively, the proposed method is of definite practical value.

High local unemployment and increased mortality in Danish adults; results from a prospective multilevel study

DEFF Research Database (Denmark)

Osler, M; Christensen, Ulla; Lund, Rikke

2003-01-01

registers. Data were pooled data from two population studies conducted in Copenhagen, Denmark. The association between unemployment at parish level and mortality was examined in Cox proportional hazard analysis. A total of 15 980 men and women, aged 20-67 years and employed at 1 January 1980, were studied...... was also a risk factor (hazard ratio(yes/no) 1.38:1.16-1.64). These estimates attenuated somewhat when other social and behavioural covariates were taken into account. The effects were similar in men and women, but the influence of individuals' unemployment experience during one and five years decreased...... gradually with increasing age. CONCLUSION: This prospective study suggests that high local unemployment and individuals' experience of unemployment increase mortality risk, even after adjustment for other social and behavioural factors....

Hypothetical high-level cognitive functions cannot be localized in the brain: another argument for a revitalized behaviorism.

Science.gov (United States)

Uttal, William R

2004-01-01

A key epistemological difference between behaviorism and cognitivism concerns their respective attitudes toward the analysis of so-called cognitive processes into functional modules. Behaviorists generally say it is not possible. Cognitivists argue that this is an achievable goal. The question has been concretized by recent developments in brain imaging technology. A consideration of the matter suggests that technical and conceptual difficulties abound in the effort to localize "high-level cognitive functions" in narrowly circumscribed regions of the brain. Some of the most serious involve the ambiguous definition of the putative mental components that are to be localized and the generally unacknowledged nonlinear complexity of both psychological processes and the brain. In addition, the imaging techniques themselves are replete with technical difficulties that raise additional questions about this particular application, even though these wonderful machines can make extraordinary contributions to our knowledge of brain anatomy and physiology. The cumulative implication of these difficulties is that the cognitive approach to the study of scientific psychology has once again set out on a search for a chimera. New approaches to behaviorism may be required to set psychology back on the correct track.

Adjuvant radiation for vulvar carcinoma: improved local control

International Nuclear Information System (INIS)

Faul, Clare M.; Mirmow, Dwight; Huang Qingshon; Gerszten, Kristina; Day, Roger; Jones, Mirka W.

1997-01-01

Purpose: Local recurrence is a significant problem following primary surgery for advanced vulva carcinoma. The objectives of this study were to evaluate the impact of adjuvant vulvar radiation on local control in high risk patients and the impact of local recurrence on overall survival. Methods and Materials: From 1980-1994, 62 patients with invasive vulva carcinoma and either positive or close (less 8 mm) margins of excision were retrospectively studied. Thirty-one patients were treated with adjuvant radiation therapy to the vulva and 31 patients were observed after surgery. Kaplan-Meier estimates and the Cox proportional hazard regression model were used to evaluate the effect of adjuvant radiation therapy on local recurrence and overall survival. Independent prognostic factors for local recurrence and survival were also assessed. Results: Local recurrence occurred in 58% of observed patients and 16% in patients treated with adjuvant radiation therapy. Adjuvant radiation therapy significantly reduced local recurrence rates in both the close margin and positive margin groups (p = 0.036, p = 0.0048). On both univariate and multivariate analysis adjuvant radiation and margins of excision were significant prognostic predictors for local control. Significant determinants of actuarial survival included International Federation of Gynecologists and Obstetricians (FIGO) stage, percentage of pathologically positive inguinal nodes and margins of excision. The positive margin observed group had a significantly poorer actuarial 5 year survival than the other groups (p = 0.0016) and adjuvant radiation significantly improved survival for this group. The 2 year actuarial survival after developing local recurrence was 25%. Local recurrence was a significant predictor for death from vulva carcinoma (risk ratio 3.54). Conclusion: Local recurrence is a common occurrence in high risk patients. In this study adjuvant radiation therapy significantly reduced local recurrence rates and

Bathymetry and digital elevation models of Coyote Creek and Alviso Slough, South San Francisco Bay, California

Science.gov (United States)

Foxgrover, Amy C.; Finlayson, David P.; Jaffe, Bruce E.; Fregoso, Theresa A.