WorldWideScience

Sample records for living systems live

  1. Living Systems Energy Module

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-26

    The Living Systems Energy Module, renamed Voyage from the Sun, is a twenty-lesson curriculum designed to introduce students to the major ways in which energy is important in living systems. Voyage from the Sun tells the story of energy, describing its solar origins, how it is incorporated into living terrestrial systems through photosynthesis, how it flows from plants to herbivorous animals, and from herbivores to carnivores. A significant part of the unit is devoted to examining how humans use energy, and how human impact on natural habitats affects ecosystems. As students proceed through the unit, they read chapters of Voyage from the Sun, a comic book that describes the flow of energy in story form (Appendix A). During the course of the unit, an ``Energy Pyramid`` is erected in the classroom. This three-dimensional structure serves as a classroom exhibit, reminding students daily of the importance of energy and of the fragile nature of our living planet. Interactive activities teach students about adaptations that allow plants and animals to acquire, to use and to conserve energy. A complete list of curricular materials and copies of all activity sheets appear in Appendix B.

  2. Adaptation in Living Systems

    Science.gov (United States)

    Tu, Yuhai; Rappel, Wouter-Jan

    2018-03-01

    Adaptation refers to the biological phenomenon where living systems change their internal states in response to changes in their environments in order to maintain certain key functions critical for their survival and fitness. Adaptation is one of the most ubiquitous and arguably one of the most fundamental properties of living systems. It occurs throughout all biological scales, from adaptation of populations of species over evolutionary time to adaptation of a single cell to different environmental stresses during its life span. In this article, we review some of the recent progress made in understanding molecular mechanisms of cellular-level adaptation. We take the minimalist (or the physicist) approach and study the simplest systems that exhibit generic adaptive behaviors, namely chemotaxis in bacterium cells (Escherichia coli) and eukaryotic cells (Dictyostelium). We focus on understanding the basic biochemical interaction networks that are responsible for adaptation dynamics. By combining theoretical modeling with quantitative experimentation, we demonstrate universal features in adaptation as well as important differences in different cellular systems. Future work in extending the modeling framework to study adaptation in more complex systems such as sensory neurons is also discussed.

  3. Radiation effects on living systems

    International Nuclear Information System (INIS)

    Hawley, N.J.

    1980-10-01

    This bibliography includes papers and reports by Atomic Energy of Canada Limited scientists concerning radiation effects on living systems. It is divided into three sections: Radiobiology, Radiation Biochemistry and Radiation Chemistry. (auth)

  4. Radiation effects on living systems

    International Nuclear Information System (INIS)

    Hawley, N.J.

    1984-04-01

    This bibliography includes papers and reports by Atomic Energy of Canada Limited scientists concerning radiation effects on living systems. It is divided into three sections: Radiobiology, Radiation Biochemistry and Radiation Chemistry. It is intended that the bibliography will be updated regularly

  5. Semiotic Scaffolding in Living Systems

    DEFF Research Database (Denmark)

    Hoffmeyer, Jesper

    2008-01-01

    The apparently purposeful nature of living systems is obtained through a sophisticated network of semiotic controls whereby biochemical, physiological and behavioral processes become tuned to the needs of the system. The operation of these semiotic controls takes place and is enabled across...... a diversity of levels. Such semiotic controls may be distinguished from ordinary deterministic control mechanisms through an inbuilt anticipatory capacity based on a distinct kind of causation that I call here "semiotic causation" to denote the bringing about of changes under the guidance of interpretation...... in a local .context. Anticipation through the skilled interpretation of indicators of temporal relations in the context of a particular survival project (or life strategy) guides organismic behavior towards local ends. This network of semiotic controls establishes an enormously complex semiotic scaffolding...

  6. Dynamical Signatures of Living Systems

    Science.gov (United States)

    Zak, M.

    1999-01-01

    One of the main challenges in modeling living systems is to distinguish a random walk of physical origin (for instance, Brownian motions) from those of biological origin and that will constitute the starting point of the proposed approach. As conjectured, the biological random walk must be nonlinear. Indeed, any stochastic Markov process can be described by linear Fokker-Planck equation (or its discretized version), only that type of process has been observed in the inanimate world. However, all such processes always converge to a stable (ergodic or periodic) state, i.e., to the states of a lower complexity and high entropy. At the same time, the evolution of living systems directed toward a higher level of complexity if complexity is associated with a number of structural variations. The simplest way to mimic such a tendency is to incorporate a nonlinearity into the random walk; then the probability evolution will attain the features of diffusion equation: the formation and dissipation of shock waves initiated by small shallow wave disturbances. As a result, the evolution never "dies:" it produces new different configurations which are accompanied by an increase or decrease of entropy (the decrease takes place during formation of shock waves, the increase-during their dissipation). In other words, the evolution can be directed "against the second law of thermodynamics" by forming patterns outside of equilibrium in the probability space. Due to that, a specie is not locked up in a certain pattern of behavior: it still can perform a variety of motions, and only the statistics of these motions is constrained by this pattern. It should be emphasized that such a "twist" is based upon the concept of reflection, i.e., the existence of the self-image (adopted from psychology). The model consists of a generator of stochastic processes which represents the motor dynamics in the form of nonlinear random walks, and a simulator of the nonlinear version of the diffusion

  7. Marine living thing processing system

    International Nuclear Information System (INIS)

    Toyoshi, Takanori; Yanagisawa, Takao; Nakamura, Toshio; Ueda, Kiyokatsu; Terada, Takeshi.

    1994-01-01

    Marine living things collected upon cleaning of a seawater intake channel are sent to a solid/liquid separator. Discharged liquids containing separated sludges enter a coagulation/precipitation vessel. Condensed sludges precipitated in the vessel are sent to a dehydrator and converted into dehydrated cakes. On the other hand, supernatants discharged from the coagulation/precipitation vessel are sent to an ultra-filtration vessel and an active carbon vessel and then discharged to the sea area at improved the water quality. Further, the dehydrated cakes comprising condensed sluges are dried by a dryer, burnt in an incinerator and then processed as wastes. On the other hand, solid materials separated by the solid/liquid separator such as shells, are crushed finely by the crusher, then dried by an air stream dryer, baked in a high temperature baking furnace to form quick lime. The quick lime is sent to a digester and modified by hydration into slaked lime and it is shipped as slaked lime products. This can simplify the control for the operation and reduce the running cost. Further, resources of marine living (shells) can be utilized. (I.N.)

  8. A Legacy for Living Systems

    DEFF Research Database (Denmark)

    who are seeking an elegant new approach to exploring highly complex systems.   "What pattern connects the crab to the lobster and the orchid to the primrose and all the four of them to me? And me to you?" - Gregory Bateson from Mind and Nature Written for: Individuals (researchers) and libraries...

  9. Adaptive Dialogue Systems for Assistive Living Environments

    Science.gov (United States)

    Papangelis, Alexandros

    2013-01-01

    Adaptive Dialogue Systems (ADS) are intelligent systems, able to interact with users via multiple modalities, such as speech, gestures, facial expressions and others. Such systems are able to make conversation with their users, usually on a specific, narrow topic. Assistive Living Environments are environments where the users are by definition not…

  10. The physics of living systems

    CERN Document Server

    Cleri, Fabrizio

    2016-01-01

    In this book, physics in its many aspects (thermodynamics, mechanics, electricity, fluid dynamics) is the guiding light on a fascinating journey through biological systems, providing ideas, examples and stimulating reflections for undergraduate physics, chemistry and life-science students, as well as for anyone interested in the frontiers between physics and biology. Rather than introducing a lot of new information, it encourages young students to use their recently acquired knowledge to start seeing the physics behind the biology. As an undergraduate textbook in introductory biophysics, it includes the necessary background and tools, including exercises and appendices, to form a progressive course. In this case, the chapters can be used in the order proposed, possibly split between two semesters. The book is also an absorbing read for researchers in the life sciences who wish to refresh or go deeper into the physics concepts gleaned in their early years of scientific training. Less physics-oriented readers m...

  11. Dynamical real numbers and living systems

    International Nuclear Information System (INIS)

    Datta, Dhurjati Prasad

    2004-01-01

    Recently uncovered second derivative discontinuous solutions of the simplest linear ordinary differential equation define not only an nonstandard extension of the framework of the ordinary calculus, but also provide a dynamical representation of the ordinary real number system. Every real number can be visualized as a living cell-like structure, endowed with a definite evolutionary arrow. We discuss the relevance of this extended calculus in the study of living systems. We also present an intelligent version of the Newton's first law of motion

  12. Spatial Models and Networks of Living Systems

    DEFF Research Database (Denmark)

    Juul, Jeppe Søgaard

    When studying the dynamics of living systems, insight can often be gained by developing a mathematical model that can predict future behaviour of the system or help classify system characteristics. However, in living cells, organisms, and especially groups of interacting individuals, a large number...... variables of the system. However, this approach disregards any spatial structure of the system, which may potentially change the behaviour drastically. An alternative approach is to construct a cellular automaton with nearest neighbour interactions, or even to model the system as a complex network...... with interactions defined by network topology. In this thesis I first describe three different biological models of ageing and cancer, in which spatial structure is important for the system dynamics. I then turn to describe characteristics of ecosystems consisting of three cyclically interacting species...

  13. Living Technology

    DEFF Research Database (Denmark)

    2010-01-01

    This book is aimed at anyone who is interested in learning more about living technology, whether coming from business, the government, policy centers, academia, or anywhere else. Its purpose is to help people to learn what living technology is, what it might develop into, and how it might impact...... our lives. The phrase 'living technology' was coined to refer to technology that is alive as well as technology that is useful because it shares the fundamental properties of living systems. In particular, the invention of this phrase was called for to describe the trend of our technology becoming...... increasingly life-like or literally alive. Still, the phrase has different interpretations depending on how one views what life is. This book presents nineteen perspectives on living technology. Taken together, the interviews convey the collective wisdom on living technology's power and promise, as well as its...

  14. Calorimetry and thermodynamics of living systems

    International Nuclear Information System (INIS)

    Lamprecht, Ingolf

    2003-01-01

    Calorimetry of living systems and classical thermodynamics developed in parallel, from Lavoisier's early ice calorimeter experiments on guinea pigs, followed by Dubrunfaut's macrocalorimetric research of fermentation processes and Atwater-Rosa's whole-body calorimetry on humans and domestic animals, to the introduction of the famous Tian-Calvet instrument that found entrance into so many different fields of biology. In this work, six examples of living-system calorimetry and thermodynamics are presented. These are: (i) glycolytic oscillations far off the thermodynamic equilibrium; (ii) growth and energy balances in fermenting and respiring yeast cultures; (iii) direct and indirect calorimetric monitoring of electrically stimulated reptile metabolism; (iv) biologic and climatic factors influencing the temperature constancy and distribution in the mound of a wood ant colony as an example of a complex ecological system; (v) energetic considerations on the clustering of European honeybees in winter as a means to save energy and stored food as well as for their Japanese counterparts in defending against hornet predators; and (vi) energetic and evolutionary aspects of the mass specific entropy production rate, the so-called bound dissipation or psiu-function. The examples presented here are just a very personal selection of living systems from a broad spectrum at all levels of complexity. Common for all of them is that they were investigated calorimetrically on the background of classical and irreversible thermodynamics

  15. Group & Intergroup Relations in Living Human Systems.

    Science.gov (United States)

    1980-06-01

    organizational diagnosis , the group is itself a living human system. A group may be underbounded, overbounded, or optimally bounded. The state of group...very im- portant to understand and to use in order to conduct organizational diagnosis " using group methods. 2 -43 (Alderfer, 1977b). The group...Boundary Relations and Organizational Diagnosis . In H. Meltzer and F.W. Wickert (eds.) Humanizing Organizational Behavior. Springfield, Illinois: Thomas

  16. A Living Military System On The Verge of Annihilation

    National Research Council Canada - National Science Library

    Abb, Madelfia

    2000-01-01

    ... organization is a living system. Recognizing the parallels between a living system and a military system's need to survive and prosper within an environment full of positive and inimical changes, this study explores the world...

  17. Thermodynamic inversion origin of living systems

    CERN Document Server

    Kompanichenko, Vladimir N

    2017-01-01

    This book discusses the theory, general principles, and energy source conditions allowing for the emergence of life in planetary systems. The author examines the material conditions found in natural hydrothermal sites, the appropriate analogs of prebiotic environments on early Earth. He provides an overview of current laboratory experiments in prebiotic materials chemistry and substantiation of a new direction for the experiments in the origin of life field. Describes thermodynamic inversion and how it relates to the living cell; Examines the current direction of experiments on prebiotic materials chemistry; Introduces and substantiates necessary conditions for the emergence of life.

  18. Anticipatory Mechanisms in Evolutionary Living Systems

    Science.gov (United States)

    Dubois, Daniel M.; Holmberg, Stig C.

    2010-11-01

    This paper deals firstly with a revisiting of Darwin's theory of Natural Selection. Darwin in his book never uses the word "evolution", but shows a clear position about mutability of species. Darwin's Natural Selection was mainly inspired by the anticipatory Artificial Selection by humans in domestication, and the Malthus struggle for existence. Darwin showed that the struggle for existence leads to the preservation of the most divergent offspring of any one species. He cited several times the canon of "Natura non facit saltum". He spoke about the origin of life from some one primordial form, into which life was first breathed. Finally, Darwin made anticipation about the future researches in psychology. This paper cites the work of Ernst Mayr who was the first, after 90 years of an intense scientific debate, to present a new and stable Darwinian paradigm as the "Evolutionary Synthesis" in 1942. To explain what is life, the Living Systems Theory (LST) by J. G. Miller is presented. It is showed that the Autopoietic Systems Theory of Varela et al is also a fundamental component of living systems. In agreement with Darwin, the natural selection is a necessary condition for transformation of biological systems, but is not a sufficient condition. Thus, in this paper we conjecture that an anticipatory evolutionary mechanism exists with the genetic code that is a self-replicating and self-modifying anticipatory program. As demonstrated by Nobel laureate McClintock, evolution in genomes is programmed. The word "program" comes from "pro-gram" meaning to write before, by anticipation, and means a plan for the programming of a mechanism, or a sequence of coded instructions that can be inserted into a mechanism, or a sequence of coded instructions, as genes of behavioural responses, that is part of an organism. For example, cell death may be programmed by what is called the apoptosis. This definitively is a great breakthrough in our understanding of biological evolution. Hence

  19. Mathematical Models and Methods for Living Systems

    CERN Document Server

    Chaplain, Mark; Pugliese, Andrea

    2016-01-01

    The aim of these lecture notes is to give an introduction to several mathematical models and methods that can be used to describe the behaviour of living systems. This emerging field of application intrinsically requires the handling of phenomena occurring at different spatial scales and hence the use of multiscale methods. Modelling and simulating the mechanisms that cells use to move, self-organise and develop in tissues is not only fundamental to an understanding of embryonic development, but is also relevant in tissue engineering and in other environmental and industrial processes involving the growth and homeostasis of biological systems. Growth and organization processes are also important in many tissue degeneration and regeneration processes, such as tumour growth, tissue vascularization, heart and muscle functionality, and cardio-vascular diseases.

  20. YouTube Live and Twitch: A Tour of User-Generated Live Streaming Systems

    OpenAIRE

    Pires , Karine; SIMON , Gwendal

    2015-01-01

    International audience; User-Generated live video streaming systems are services that allow anybody to broadcast a video stream over the Internet. These Over-The-Top services have recently gained popularity, in particular with e-sport, and can now be seen as competitors of the traditional cable TV. In this paper, we present a dataset for further works on these systems. This dataset contains data on the two main user-generated live streaming systems: Twitch and the live service of YouTube. We ...

  1. Cognitive assisted living ambient system: a survey

    Directory of Open Access Journals (Sweden)

    Ruijiao Li

    2015-11-01

    Full Text Available The demographic change towards an aging population is creating a significant impact and introducing drastic challenges to our society. We therefore need to find ways to assist older people to stay independently and prevent social isolation of these population. Information and Communication Technologies (ICT provide various solutions to help older adults to improve their quality of life, stay healthier, and live independently for a time. Ambient Assisted Living (AAL is a field to investigate innovative technologies to provide assistance as well as healthcare and rehabilitation to impaired seniors. The paper provides a review of research background and technologies of AAL.

  2. Healthy Living

    Science.gov (United States)

    ... Health Menu Topics Environment & Health Healthy Living Pollution Reduce, Reuse, Recycle Science – How It Works The Natural World Games ... Lessons Topics Expand Environment & Health Healthy Living Pollution Reduce, Reuse, Recycle Science – How It Works The Natural World Games ...

  3. Assisted Living

    Science.gov (United States)

    ... it, too. Back to top What is the Cost for Assisted Living? Although assisted living costs less than nursing home ... Primarily, older persons or their families pay the cost of assisted living. Some health and long-term care insurance policies ...

  4. Generating minimal living systems from non-living materials and increasing their evolutionary abilities

    DEFF Research Database (Denmark)

    Rasmussen, Steen; Constantinescu, Adi; Svaneborg, Carsten

    2016-01-01

    We review lessons learned about evolutionary transitions from a bottom up construction of minimal life. We use a particular systemic protocell design process as a starting point for exploring two fundamental questions: (1) how may minimal living systems emerge from nonliving materials? - and (2......) how may minimal living systems support increasingly more evolutionary richness? Under (1) we present what has been accomplished so far and discuss the remaining open challenges and their possible solutions. Under (2) we present a design principle we have utilized successfully both for our...

  5. A Reasoning Technique for Taxonomy Expert System of Living Organisms

    OpenAIRE

    desiani, anita; Firdaus, Firdaus; Maiyanti, Sri Indra

    2016-01-01

    Taxonomy of living organisms can help scientists to sort organisms in order and help them to identify new organisms by finding out which their groups. It also is easier to study organisms when they are sorted in groups. Taxonomy of living organisms system is a important basic part of ecology system. Researcher should know about any organisms that they noted in an ecology. Integration between classification taxonomy of Living Organisms and technology information will have many advantages for ...

  6. Live Well

    Science.gov (United States)

    ... Health Conditions Live Well Mental Health Substance Use Smoking Healthy Diet Physical Activity Family Planning Living with HIV: Travel ... to his or her health and well-being. Smoking - Tobacco use is the ... year. Healthy Diet - No matter your HIV status, healthy eating is ...

  7. Healthy living

    Science.gov (United States)

    ... living URL of this page: //medlineplus.gov/ency/article/002393.htm Healthy living To use the sharing features on this page, please enable JavaScript. Good health habits can allow you to avoid illness and improve your quality of life. The following steps will help you ...

  8. An integrated smart system for ambient-assisted living

    CSIR Research Space (South Africa)

    Foko, Thato E

    2013-08-01

    Full Text Available Ambient-assisted living (AAL) is an initiative to extend the time the elderly can live in their home environment by increasing their autonomy and assisting them carry out their daily activities. AAL systems exploit information and communication...

  9. Living Color Frame System: PC graphics tool for data visualization

    Science.gov (United States)

    Truong, Long V.

    1993-01-01

    Living Color Frame System (LCFS) is a personal computer software tool for generating real-time graphics applications. It is highly applicable for a wide range of data visualization in virtual environment applications. Engineers often use computer graphics to enhance the interpretation of data under observation. These graphics become more complicated when 'run time' animations are required, such as found in many typical modern artificial intelligence and expert systems. Living Color Frame System solves many of these real-time graphics problems.

  10. Living PSA

    International Nuclear Information System (INIS)

    Evans, M.G.K.

    1997-01-01

    The aim of this presentation is to gain an understanding of the requirements for a PSA to be considered a Living PSA. The presentation is divided into the following topics: Definition; Planning/Documentation; Task Performance; Maintenance; Management. 4 figs

  11. Assisted Living

    Science.gov (United States)

    ... a resident's needs depends as much on the philosophy and services of the assisted living facility as it does on the quality of care. The Administration on Aging, a part of the U.S. Department of Health and Human Services (HHS), offers these suggestions to help you ...

  12. Easier living?

    DEFF Research Database (Denmark)

    Høholt, Stine

    2005-01-01

    I ph.d.-projektet: "Easier Living? Streamline design og den æstetiserede livsverden" analyseres 1930'ernes Streamline-bevægelse, som tilhører den amerikanske modernisme inden for industrielt produktdesign. Bevægelsens glatte, strømlinede produkter bliver med deres enorme udbredelse det historiske...

  13. The Gouy-Stodola Theorem in Bioenergetic Analysis of Living Systems (Irreversibility in Bioenergetics of Living Systems

    Directory of Open Access Journals (Sweden)

    Umberto Lucia

    2014-09-01

    Full Text Available Thermodynamics studies the transformations of energy occurring in open systems. Living systems, with particular reference to cells, are complex systems in which energy transformations occur. Thermo-electro-chemical processes and transports occur across their border, the cells membranes. These processes take place with important differences between healthy and diseased states. In particular, different thermal and biochemical behaviours can be highlighted between these two states and they can be related to the energy transformations inside the living systems, in particular the metabolic behaviour. Moreover, living systems waste heat. This heat is the consequence of the internal irreversibility. Irreversibility is effectively studied by using the Gouy-Stodola theorem. Consequently, this approach can be introduced in the analysis of the states of living systems, in order to obtain a unifying approach to study them. Indeed, this approach allows us to consider living systems as black boxes and analyze only the inflows and outflows and their changes in relation to the modification of the environment, so information on the systems can be obtained by analyzing their behaviour in relation to the modification of external perturbations. This paper presents a review of the recent results obtained in the thermodynamics analysis of cell systems.

  14. Fifty Years of Physics of Living Systems.

    Science.gov (United States)

    Latash, Mark L

    2016-01-01

    The equilibrium-point hypothesis and its more recent version, the referent configuration hypothesis, represent the physical approach to the neural control of action. This hypothesis can be naturally combined with the idea of hierarchical control of movements and of synergic organization of the abundant systems involved in all actions. Any action starts with defining trajectories of a few referent coordinates for a handful of salient task-specific variables. Further, referent coordinates at hierarchically lower levels emerge down to thresholds of the tonic stretch reflex for the participating muscles. Stability of performance with respect to salient variables is reflected in the structure of inter-trial variance and phenomena of motor equivalence. Three lines of recent research within this framework are reviewed. First, synergic adjustments of the referent coordinate and apparent stiffness have been demonstrated during finger force production supporting the main idea of control with referent coordinates. Second, the notion of unintentional voluntary movements has been introduced reflecting unintentional drifts in referent coordinates. Two types of unintentional movements have been observed with different characteristic times. Third, this framework has been applied to studies of impaired movements in neurological patients. Overall, the physical approach searching for laws of nature underlying biological movement has been highly stimulating and productive.

  15. A quest towards a mathematical theory of living systems

    CERN Document Server

    Bellomo, Nicola; Gibelli, Livio; Outada, Nisrine

    2017-01-01

    This monograph aims to lay the groundwork for the design of a unified mathematical approach to the modeling and analysis of large, complex systems composed of interacting living things. Drawing on twenty years of research in various scientific fields, it explores how mathematical kinetic theory and evolutionary game theory can be used to understand the complex interplay between mathematical sciences and the dynamics of living systems. The authors hope this will contribute to the development of new tools and strategies, if not a new mathematical theory. The first chapter discusses the main features of living systems and outlines a strategy for their modeling. The following chapters then explore some of the methods needed to potentially achieve this in practice. Chapter Two provides a brief introduction to the mathematical kinetic theory of classical particles, with special emphasis on the Boltzmann equation; the Enskog equation, mean field models, and Monte Carlo methods are also briefly covered. Chapter Three...

  16. Austrian Lives

    OpenAIRE

    Bischof, Günter; Plasser, Fritz; Maltschnig, Eva

    2012-01-01

    Writing biographies for a long time had been a male hegemonic project. Ever since Plutarch and Sueton composed their vitae of the greats of classical antiquity, to the medieval obsession with the hagiographies of holy men (and a few women) and saints, Vasari's lives of great Renaissance artists, down to the French encyclopedists, Dr. Johnson and Lytton Strachey, as well as Ranke and Droysen the genre of biographical writing has become increasingly more refined. In the twentieth century male p...

  17. Applying Formal Verification Techniques to Ambient Assisted Living Systems

    Science.gov (United States)

    Benghazi, Kawtar; Visitación Hurtado, María; Rodríguez, María Luisa; Noguera, Manuel

    This paper presents a verification approach based on timed traces semantics and MEDISTAM-RT [1] to check the fulfillment of non-functional requirements, such as timeliness and safety, and assure the correct functioning of the Ambient Assisted Living (AAL) systems. We validate this approach by its application to an Emergency Assistance System for monitoring people suffering from cardiac alteration with syncope.

  18. Chance vs. necessity in living systems: a false antinomy.

    Science.gov (United States)

    Buiatti, Marcello; Buiatti, Marco

    2008-01-01

    The concepts of order and randomness are crucial to understand 'living systems' structural and dynamical rules. In the history of biology, they lay behind the everlasting debate on the relative roles of chance and determinism in evolution. Jacques Monod [1970] built a theory where chance (randomness) and determinism (order) were considered as two complementary aspects of life. In the present paper, we will give an up to date version of the problem going beyond the dichotomy between chance and determinism. To this end, we will first see how the view on living systems has evolved from the mechanistic one of the 19th century to the one stemming from the most recent literature, where they emerge as complex systems continuously evolving through multiple interactions among their components and with the surrounding environment. We will then report on the ever increasing evidence of "friendly" co-existence in living beings between a number of "variability generators", fixed by evolution, and the "spontaneous order" derived from interactions between components. We will propose that the "disorder" generated is "benevolent" because it allows living systems to rapidly adapt to changes in the environment by continuously changing, while keeping their internal harmony.

  19. Living Lands

    DEFF Research Database (Denmark)

    Christensen, Suna Møller

    2015-01-01

    , hunters attended to questions like safe-journeying on ice or the role of natural surroundings in children’s education, in ways revealing a relational perception of ‘nature’ and dissolving culture-nature dualisms. Hunters’ experiences in living the land afforded children a dwelling position from which...... to grow with the features of the land. Framed this way, ‘nature’ was regarded as part of the social world. I suggest that learning among Arctic hunters is social and twofold. First, we can learn how human-environment relations influence individual life trajectories. Secondly, ‘nature’ as part...

  20. Lively package

    International Nuclear Information System (INIS)

    Jaremko, G.

    1997-01-01

    Progress on the Lloydminster Heavy Oil Interpretive Centre, sponsored by the Lloydminster Oilfield Technical Society and expected to open in late 1998, was discussed. Some $150,000 of the $750,000 budget is already in the bank, and another $150,000 is in the pipeline. The Centre will be added to an existing and well-established visitor's site. It is reported to contain a lively and imaginatively-designed exhibit package, and promises to become a combination of educational tool and tourist attraction for the town of Lloydminster, Saskatchewan, in the heart of heavy oil country

  1. The Systemic Theory of Living Systems and Relevance to CAM

    Directory of Open Access Journals (Sweden)

    José A. Olalde Rangel

    2005-01-01

    Full Text Available The Systemic Theory of Living Systems is being published in several parts in eCAM. The theory is axiomatic. It originates from the phenomenological idea that physiological health is based on three factors: integrity of its structure or organization, O, functional organic energy reserve, E, and level of active biological intelligence, I. From the theory is derived a treatment strategy called Systemic Medicine (SM. This is based on identifying and prescribing phytomedicines and/or other medications that strengthen each factor. Energy-stimulating phytomedicines increase available energy and decrease total entropy of an open biological system by providing negative entropy. The same occurs with phytomedicines that act as biological intelligence modulators. They should be used as the first line of treatment in all ailments, since all pathologies, by definition, imply a higher than normal organic entropy. SM postulates that the state of health, H, of an individual, is effectively equal to the product of the strength of each factor H = O × E × I. SM observes that when all three factors are brought back to ideal levels, patients' conditions begin the recovery to normal health.

  2. A microcomputer-based daily living activity recording system.

    Science.gov (United States)

    Matsuoka, Shingo; Yonezawa, Yoshiharu; Maki, Hiromichi; Ogawa, Hidekuni; Hahn, Allen W; Thayer, Julian F; Caldwell, W Morton

    2003-01-01

    A new daily living activity recording system has been developed for monitoring health conditions and living patterns, such as respiration, posture, activity/rest ratios and general activity level. The system employs a piezoelectric sensor, a dual axis accelerometer, two low-power active filters, a low-power 8-bit single chip microcomputer and a 128 MB compact flash memory. The piezoelectric sensor, whose electrical polarization voltage is produced by mechanical strain, detects body movements. Its high-frequency output components reflect body movements produced by walking and running activities, while the low frequency components are mainly respiratory. The dual axis accelerometer detects, from body X and Y tilt angles, whether the patient is standing, sitting or lying down (prone, supine, left side or right side). The detected respiratory, behavior and posture signals are stored by the compact flash memory. After recording, these data are downloaded to a desktop computer and analyzed.

  3. Long-Lived In-Situ Solar System Explorer (LLISSE)

    Science.gov (United States)

    Kremic, Tibor; Hunter, Gary; Rock, Jennifer

    2017-01-01

    This presentation provides an update on development of the Long-Lived In-situ Solar System Explorer (LLISSE). LLISSE is a small probe being developed to provide long-term measurements of simple but important scientific parameters from the surface of Venus. High level summary of recent activities and progress is provided. LLISSE is a small and completely independent probe for Venus surface applications

  4. Living is information processing: from molecules to global systems

    OpenAIRE

    Farnsworth, Keith D.; Nelson, John; Gershenson, Carlos

    2012-01-01

    We extend the concept that life is an informational phenomenon, at every level of organisation, from molecules to the global ecological system. According to this thesis: (a) living is information processing, in which memory is maintained by both molecular states and ecological states as well as the more obvious nucleic acid coding; (b) this information processing has one overall function - to perpetuate itself; and (c) the processing method is filtration (cognition) of, and synthesis of, info...

  5. [Living better or living longer].

    Science.gov (United States)

    Sauvy, A

    1987-01-01

    It has been just 2 centuries since France began to struggle seriously against mortality and excess fertility. Life expectancy, which for millenia had been under 30 years at birth, began to increase because of the discovery of effective treatments, improved production and standards of living, and access of large numbers of persons to health care. France, in the 2nd half of the 18th century, became the first country in which fertility regulation was achieved on a wide scale. The failure of England, a country of similar culture, to follow suit until a century later remains unexplained. After World War II, simple and fairly inexpensive means of mortality control, such as vaccines and water purifiers, became widely distributed throughout the developing world. These countries, which traditionally had mortality rates of 35 or 40/1000 and fertility of 40-45/1000, experienced rapid declines in mortality rates while their fertility remained constant or even increased. Because antinatal techniques diffused so much more slowly, the equilibrium of births and deaths was disturbed as rates of increase of 2 or 3% per year became common. Although the inhabitants of poor countries were not concerned, perhaps through ignorance of what was occurring, the rich countries were alarmed by the increase. Their principal objective became to spread contraception in the poor countries. The available methods at the time, however, were none too reliable. When oral contraceptive pills became available, fertility dropped to very low levels in Europe but such factors as cost and illiteracy discouraged use in many underdeveloped countries. Fertility declined in a few insular states such as Hong Kong, Taiwan, and Singapore even before the appearance of pills. Life expectancies in developing countries except a few in Africa have increased since World War II and are now higher than in Europe at the turn of the century. "Health for all by the year 2000" is an astonishing slogan for a serious

  6. Passive wireless sensor systems can recognize activites of daily living.

    Science.gov (United States)

    Urwyler, Prabitha; Stucki, Reto; Muri, Rene; Mosimann, Urs P; Nef, Tobias

    2015-08-01

    The ability to determine what activity of daily living a person performs is of interest in many application domains. It is possible to determine the physical and cognitive capabilities of the elderly by inferring what activities they perform in their houses. Our primary aim was to establish a proof of concept that a wireless sensor system can monitor and record physical activity and these data can be modeled to predict activities of daily living. The secondary aim was to determine the optimal placement of the sensor boxes for detecting activities in a room. A wireless sensor system was set up in a laboratory kitchen. The ten healthy participants were requested to make tea following a defined sequence of tasks. Data were collected from the eight wireless sensor boxes placed in specific places in the test kitchen and analyzed to detect the sequences of tasks performed by the participants. These sequence of tasks were trained and tested using the Markov Model. Data analysis focused on the reliability of the system and the integrity of the collected data. The sequence of tasks were successfully recognized for all subjects and the averaged data pattern of tasks sequences between the subjects had a high correlation. Analysis of the data collected indicates that sensors placed in different locations are capable of recognizing activities, with the movement detection sensor contributing the most to detection of tasks. The central top of the room with no obstruction of view was considered to be the best location to record data for activity detection. Wireless sensor systems show much promise as easily deployable to monitor and recognize activities of daily living.

  7. Synergetic approach of norm and pathology of living system functioning

    International Nuclear Information System (INIS)

    Asqarov, B.; Oksengendler, B.L.; Turaeva, N.N.; Karimov, Z.; Rafikova, Z.B.

    2011-01-01

    Basing on fundamental idea of dynamical chaos and strict periodicity in living systems the new peculiarities in brain and heart functioning have been reveled. It has been shown that the development of pathological states of brain and heart activities occurs by means of both increase and decrease of chaos components in brain activity and heart rhythm. It has been defined the 'health range' for brain and heart functioning in norm, and the method of recovery of the health range is proposed from the electrocardiograms and electroencephalograms data (authors).

  8. We need theoretical physics approaches to study living systems

    Science.gov (United States)

    Blagoev, Krastan B.; Shukla, Kamal; affil="3" >Herbert Levine,

    2013-08-01

    Living systems, as created initially by the transition from assemblies of large molecules to self-reproducing information-rich cells, have for centuries been studied via the empirical toolkit of biology. This has been a highly successful enterprise, bringing us from the vague non-scientific notions of vitalism to the modern appreciation of the biophysical and biochemical bases of life. Yet, the truly mind-boggling complexity of even the simplest self-sufficient cells, let alone the emergence of multicellular organisms, of brain and consciousness, and to ecological communities and human civilizations, calls out for a complementary approach. In this editorial, we propose that theoretical physics can play an essential role in making sense of living matter. When faced with a highly complex system, a physicist builds simplified models. Quoting Philip W Anderson's Nobel prize address, 'the art of model-building is the exclusion of real but irrelevant parts of the problem and entails hazards for the builder and the reader. The builder may leave out something genuinely relevant and the reader, armed with too sophisticated an experimental probe, may take literally a schematized model. Very often such a simplified model throws more light on the real working of nature....' In his formulation, the job of a theorist is to get at the crux of the system by ignoring details and yet to find a testable consequence of the resulting simple picture. This is rather different than the predilection of the applied mathematician who wants to include all the known details in the hope of a quantitative simulacrum of reality. These efforts may be practically useful, but do not usually lead to increased understanding. To illustrate how this works, we can look at a non-living example of complex behavior that was afforded by spatiotemporal patterning in the Belousov-Zhabotinsky reaction [1]. Physicists who worked on this system did not attempt to determine all the relevant chemical intermediates

  9. Solar System Symphony: Combining astronomy with live classical music

    Science.gov (United States)

    Kremer, Kyle; WorldWide Telescope

    2017-01-01

    Solar System Symphony is an educational outreach show which combines astronomy visualizations and live classical music. As musicians perform excerpts from Holst’s “The Planets” and other orchestral works, visualizations developed using WorldWide Telescope and NASA images and animations are projected on-stage. Between each movement of music, a narrator guides the audience through scientific highlights of the solar system. The content of Solar System Symphony is geared toward a general audience, particularly targeting K-12 students. The hour-long show not only presents a new medium for exposing a broad audience to astronomy, but also provides universities an effective tool for facilitating interdisciplinary collaboration between two divergent fields. The show was premiered at Northwestern University in May 2016 in partnership with Northwestern’s Bienen School of Music and was recently performed at the Colburn Conservatory of Music in November 2016.

  10. Synthetic Biology: Engineering Living Systems from Biophysical Principles.

    Science.gov (United States)

    Bartley, Bryan A; Kim, Kyung; Medley, J Kyle; Sauro, Herbert M

    2017-03-28

    Synthetic biology was founded as a biophysical discipline that sought explanations for the origins of life from chemical and physical first principles. Modern synthetic biology has been reinvented as an engineering discipline to design new organisms as well as to better understand fundamental biological mechanisms. However, success is still largely limited to the laboratory and transformative applications of synthetic biology are still in their infancy. Here, we review six principles of living systems and how they compare and contrast with engineered systems. We cite specific examples from the synthetic biology literature that illustrate these principles and speculate on their implications for further study. To fully realize the promise of synthetic biology, we must be aware of life's unique properties. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  11. Digital Living at Home

    DEFF Research Database (Denmark)

    Andersen, Pernille Viktoria Kathja; Christiansen, Ellen Tove

    2013-01-01

    of these user voices has directed us towards a ‘home-keeping’ design discourse, which opens new horizons for design of digital home control systems by allowing users to perform as self-determined controllers and groomers of their habitat. The paper concludes by outlining the implications of a ‘home......Does living with digital technology inevitably lead to digital living? Users talking about a digital home control system, they have had in their homes for eight years, indicate that there is more to living with digital technology than a functional-operational grip on regulation. Our analysis......-keeping’ design discourse....

  12. Magnetic resonance imaging of living systems by remote detection

    Science.gov (United States)

    Wemmer, David; Pines, Alexander; Bouchard, Louis; Xu, Shoujun; Harel, Elad; Budker, Dmitry; Lowery, Thomas; Ledbetter, Micah

    2013-10-29

    A novel approach to magnetic resonance imaging is disclosed. Blood flowing through a living system is prepolarized, and then encoded. The polarization can be achieved using permanent or superconducting magnets. The polarization may be carried out upstream of the region to be encoded or at the place of encoding. In the case of an MRI of a brain, polarization of flowing blood can be effected by placing a magnet over a section of the body such as the heart upstream of the head. Alternatively, polarization and encoding can be effected at the same location. Detection occurs at a remote location, using a separate detection device such as an optical atomic magnetometer, or an inductive Faraday coil. The detector may be placed on the surface of the skin next to a blood vessel such as a jugular vein carrying blood away from the encoded region.

  13. Intracellular Chemistry: Integrating Molecular Inorganic Catalysts with Living Systems.

    Science.gov (United States)

    Ngo, Anh H; Bose, Sohini; Do, Loi H

    2018-03-23

    This concept article focuses on the rapid growth of intracellular chemistry dedicated to the integration of small-molecule metal catalysts with living cells and organisms. Although biological systems contain a plethora of biomolecules that can deactivate inorganic species, researchers have shown that small-molecule metal catalysts could be engineered to operate in heterogeneous aqueous environments. Synthetic intracellular reactions have recently been reported for olefin hydrogenation, hydrolysis/oxidative cleavage, azide-alkyne cycloaddition, allylcarbamate cleavage, C-C bond cross coupling, and transfer hydrogenation. Other promising targets for new biocompatible reaction discovery will also be discussed, with a special emphasis on how such innovations could lead to the development of novel technologies and chemical tools. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Living with endometriosis

    Science.gov (United States)

    Pelvic pain - living with endometriosis; Endometrial implant - living with endometriosis; Endometrioma - living with endometriosis ... counter pain relievers can reduce the pain of endometriosis. These include: Ibuprofen (Advil) Naproxen (Aleve) Acetaminophen (Tylenol) ...

  15. Live Mobile Distance Learning System for Smart Devices

    Directory of Open Access Journals (Sweden)

    Jang Ho Lee

    2015-03-01

    Full Text Available In recent years, mobile and ubiquitous computing has emerged in our daily lives, and extensive studies have been conducted in various areas using smart devices, such as tablets, smartphones, smart TVs, smart refrigerators, and smart media devices, in order to realize this computing technology. Especially, the integration of mobile networking technology and intelligent mobile devices has made it possible to develop the advanced mobile distance learning system that supports portable smart devices such as smartphones and tablets for the future IT environment. We present a synchronous mobile learning system that enables both instructor and student to participate in distance learning with their tablets. When an instructor gives a lecture using a tablet with front-face camera by bringing up slides and making annotations on them, students in the distance can watch the instructor and those slides with annotation on their own tablets in real time. A student can also ask a question or have a discussion together using the text chat feature of the system during a learning session. We also show the user evaluation of the system. A user survey shows that about 67% are in favor of the prototype of the system.

  16. Allergy, living and learning

    DEFF Research Database (Denmark)

    Chivato, T; Valovirta, E; Dahl, R

    2012-01-01

    Allergy Living and Learning (ALL) is a European initiative designed to increase knowledge and understanding of people living with allergies in order to improve respiratory allergy care.......Allergy Living and Learning (ALL) is a European initiative designed to increase knowledge and understanding of people living with allergies in order to improve respiratory allergy care....

  17. Living with systemic lupus erythematosus in the developing world.

    Science.gov (United States)

    Phuti, A; Schneider, M; Tikly, M; Hodkinson, B

    2018-03-26

    Most of our understanding of SLE and its negative impact originates from developed countries. This review aims to collate existing literature on Health-Related Quality of Life (HRQoL) in SLE patients living in developing countries to identify the gaps for the focus of future research. A narrative literature review was compiled using selected MeSH terms to search EBSCOHOST for articles published between January 1975 and February 2018 pertaining to HRQoL in SLE patients in developing countries. 31 studies from 11 countries were included for analysis. Only one longitudinal, one randomized controlled trial (RCT), one qualitative study, and two intervention studies were found. High disease activity and organ damage were associated with poor functional ability, mental health and low socio-economic status (SES). Poor SES is a recurring theme in developing countries, and worsens all SLE outcomes by reducing access to healthcare, mental, social and emotional support systems. In developing countries, SLE has a globally negative impact on patients' HRQoL, similar to that seen in developed countries. There is an urgent need for more HRQoL studies, and in particular, longitudinal, qualitative and interventional studies in these countries to investigate unmet needs, and to explore novel strategies to improve patient outcomes.

  18. Security warning method and system for worker safety during live-line working

    Science.gov (United States)

    Jiang, Chilong; Zou, Dehua; Long, Chenhai; Yang, Miao; Zhang, Zhanlong; Mei, Daojun

    2017-09-01

    Live-line working is an essential part in the operations in an electric power system. Live-line workers are required to wear shielding clothing. Shielding clothing, however, acts as a closed environment for the human body. Working in a closed environment for a long time can change the physiological responses of the body and even endanger personal safety. According to the typical conditions of live-line working, this study synthesizes environmental factors related to shielding clothing and the physiological factors of the body to establish the heart rate variability index RMSSD and the comprehensive security warning index SWI. On the basis of both indices, this paper proposes a security warning method and system for the safety live-line workers. The system can monitor the real-time status of workers during live-line working to provide security warning and facilitate the effective safety supervision by the live operation center during actual live-line working.

  19. Living with Lupus (For Parents)

    Science.gov (United States)

    ... Videos for Educators Search English Español Living With Lupus KidsHealth / For Parents / Living With Lupus What's in ... disease for both doctors and their patients. About Lupus A healthy immune system produces proteins called antibodies ...

  20. PREFACE: International & Interdisciplinary Workshop on Novel Phenomena in Integrated Complex Sciences: from Non-living to Living Systems

    Science.gov (United States)

    Yoshimura, Kazuyoshi; Ohta, Hiroto; Murase, Masatoshi; Nishimura, Kazuo

    2012-03-01

    In this workshop recent advancements in experiments and theories were discussed on magnetism and superconductivity, emergent phenomena in biological material, chemical properties and economic problems of non-living and living systems. The aim of the workshop was to discuss old, but also new problems from a multidisciplinary perspective, and to understand the general features behind diversity in condensed matter physics, experimental chemistry and physics in biology and economic science. The workshop was broadly based, and was titled 'International & Interdisciplinary Workshop on Novel Phenomena in Integrated Complex Sciences from Non-living to Living Systems'. However, the primary focus was on magnetism and superconductivity, and NMR research into strongly correlated electrons. The meeting was held as an ICAM workshop, upon official approval in January 2010. Both young scientists and graduate students were invited. We hope that these young scientists had the chance to talk with invited speakers and organizers on their own interests. We thank the participants who contributed through their presentations, discussions and these papers to the advancement of the subject and our understanding. The proceedings are published here in the Journal of Physics: Conference Series (UK). We thank the International Advisory Committee for their advice and guidance: Evgeny Antipov Moscow State University, Russia Nicholas Curro University of California, Davis, USA Minghu Fang Zhejiang University, China Jurgen Haase University of Leipzig, Germany Takashi Imai McMaster University, Canada Peter Lemmens TU Braunschweig, Germany Herwig Michor Vienna TU, Austria Takamasa Momose University of British Columbia, Canada Raivo Stern NICPB, Estonia Louis Taillefer University of Sherbrooke, Canada Masashi Takigawa University of Tokyo, Japan This workshop was mainly organized by the International Research Unit of Integrated Complex System Science, Kyoto University, and was supported by ICAM

  1. Evolving the Living With a Star Data System Definition

    Science.gov (United States)

    Otranto, J. F.; Dijoseph, M.

    2003-12-01

    NASA's Living With a Star (LWS) Program is a space weather-focused and applications-driven research program. The LWS Program is soliciting input from the solar, space physics, space weather, and climate science communities to develop a system that enables access to science data associated with these disciplines, and advances the development of discipline and interdisciplinary findings. The LWS Program will implement a data system that builds upon the existing and planned data capture, processing, and storage components put in place by individual spacecraft missions and also inter-project data management systems, including active and deep archives, and multi-mission data repositories. It is technically feasible for the LWS Program to integrate data from a broad set of resources, assuming they are either publicly accessible or allow access by permission. The LWS Program data system will work in coordination with spacecraft mission data systems and science data repositories, integrating their holdings using a common metadata representation. This common representation relies on a robust metadata definition that provides journalistic and technical data descriptions, plus linkages to supporting data products and tools. The LWS Program intends to become an enabling resource to PIs, interdisciplinary scientists, researchers, and students facilitating both access to a broad collection of science data, as well as the necessary supporting components to understand and make productive use of these data. For the LWS Program to represent science data that are physically distributed across various ground system elements, information will be collected about these distributed data products through a series of LWS Program-created agents. These agents will be customized to interface or interact with each one of these data systems, collect information, and forward any new metadata records to a LWS Program-developed metadata library. A populated LWS metadata library will function as a

  2. Living Gluten Free

    Science.gov (United States)

    ... Disease" Articles Celiac Disease Changes Everything / What is Celiac Disease? / Symptoms, Diagnosis & Treatment / Four Inches and Seven Pounds… / Learning to Live Well with Celiac Disease / Living Gluten-Free Spring 2015 Issue: Volume 10 ...

  3. Modelling live forensic acquisition

    CSIR Research Space (South Africa)

    Grobler, MM

    2009-06-01

    Full Text Available This paper discusses the development of a South African model for Live Forensic Acquisition - Liforac. The Liforac model is a comprehensive model that presents a range of aspects related to Live Forensic Acquisition. The model provides forensic...

  4. Ability of Accelerator-Driven Systems (ADS) to Transmute Long Lived Fission Fragments

    International Nuclear Information System (INIS)

    Nguyen Mong Giao; Nguyen Thi Ai Thu; Tu Thanh Danh; Tran Thanh Dung; Huynh, Thi Kim Chi

    2010-12-01

    This paper presents the research results of the possibility to transmute the long-lived radioactive isotopes into stable or short-lived, mainly the long-lived fission fragments as 99 Tc, 127 I, 129 I, 181 Ta, 107 Ag, 109 Ag by accelerator-driven systems. We use semi-empirical formulas to establish our calculating code with the support of computer programs. (author)

  5. NASA Advanced Explorations Systems: Concepts for Logistics to Living

    Science.gov (United States)

    Shull, Sarah A.; Howe, A. Scott; Flynn, Michael T.; Howard, Robert

    2012-01-01

    The NASA Advanced Exploration Systems (AES) Logistics Reduction and Repurposing (LRR) project strives to enable a largely mission-independent cradle-to-grave-to-cradle approach to minimize logistics contributions to total mission architecture mass. The goals are to engineer logistics materials, common crew consumables, and container configurations to meet the following five basic goals: 1. Minimize intrinsic logistics mass and improve ground logistics flexibility. 2. Allow logistics components to be directly repurposed for on-orbit non-logistics functions (e.g., crew cabin outfitting) thereby indirectly reducing mass/volume. 3. Compact and process logistics that have not been directly repurposed to generate useful on-orbit components and/or compounds (e.g., radiation shielding, propellant, other usable chemical constituents). 4. Enable long-term stable storage and disposal of logistics end products that cannot be reused or repurposed (e.g., compaction for volume reduction, odor control, and maintenance of crew cabin hygienic conditions). 5. Allow vehicles in different mission phases to share logistics resources. This paper addresses the work being done to meet the second goal, the direct repurposing of logistics components to meet other on-orbit needs, through a strategy termed Logistics to Living (L2L). L2L has several areas but can be defined as repurposing or converting logistical items (bags, containers, foam, components, etc.) into useful crew items or life support augmentation on-orbit after they have provided their primary logistics function. The intent is that by repurposing items, dedicated crew items do not have to be launched and overall launch mass is decreased. For non-LEO missions, the vehicle interior volume will be relatively fixed so L2L will enable this volume to be used more effectively through reuse and rearrangement of logistical components. Past work in the area of L2L has already conceptually developed several potential technologies [Howe

  6. Self-adhesive microculture system for extended live cell imaging.

    Science.gov (United States)

    Skommer, J; McGuinness, D; Wlodkowic, D

    2011-06-01

    Gas permeable and biocompatible soft polymers are convenient for biological applications. Using the soft polymer poly(dimethylsiloxane) (PDMS), we established a straightforward technique for in-house production of self-adhesive and optical grade microculture devices. A gas permeable PDMS layer effectively protects against medium evaporation, changes in osmolarity, contamination and drug diffusion. These chip-based devices can be used effectively for long term mammalian cell culture and support a range of bioassays used in pharmacological profiling of anti-cancer drugs. Results obtained on a panel of hematopoietic and solid tumor cell lines during screening of investigative anti-cancer agents corresponded well to those obtained in a conventional cell culture on polystyrene plates. The cumulative correlation analysis of multiple cell lines and anti-cancer drugs showed no adverse effects on cell viability or cell growth retardation during microscale static cell culture. PDMS devices also can be custom modified for many bio-analytical purposes and are interfaced easily with both inverted and upright cell imaging platforms. Moreover, PDMS microculture devices are suitable for extended real time cell imaging. Data from the multicolor, real time analysis of apoptosis on human breast cancer MCF-7 cells provided further evidence that elimination of redundant centrifugation/washing achieved during microscale real time analysis facilitates preservation of fragile apoptotic cells and provides dynamic cellular information at high resolution. Because only small reaction volumes are required, such devices offer reduced use of consumables as well as simplified manipulations during all stages of live cell imaging.

  7. Live your questions now

    OpenAIRE

    Brownrigg, Jenny

    2016-01-01

    'Live Your Questions Now' is a case study for Cubitt Education's publication 'Aging in Public: creative practice in ageing and the public realm from across the UK', edited by Daniel Baker and published by Cubitt Gallery, Studios and Education, London in 2016. The publication was linked to Cubitt's programme 'Public Wisdom' (2011-2015). My case study is about 'Live your questions now', a group exhibition I curated in 2011 for Mackintosh Museum, The Glasgow School of Art. 'Live your questions n...

  8. Administration for Community Living

    Science.gov (United States)

    ... 15, 2017 Grants from the National Institute on Disability, Independent Living, and Rehabilitation Research ... integration, and inclusion throughout life Other ACL Sites Eldercare Locator OlderIndians. ...

  9. Living the Utopia

    DEFF Research Database (Denmark)

    Davis, John; Warring, Anette Elisabeth

    2011-01-01

    This article examines experiments in communal living in Britain and Denmark in the early 1970s, using life-story interviews from seventeen members of two British and two Danish communes. It examines communal living as a fusion of radical political principles with the practice of experimental...... collective living. It concludes that the movement's egalitarian principles of resource-sharing, gender equality and the avoidance of hierarchies were broadly achieved, even if the movement obviously did not realize its more ambitious objective of undermining the bourgeois family. Though none...... of the interviewees lives communally now, most remain faithful to the principles behind the movement....

  10. Restoring nervous system structure and function using tissue engineered living scaffolds

    Institute of Scientific and Technical Information of China (English)

    Laura A Struzyna; James P Harris; Kritika S Katiyar; H Isaac Chen; D KacyCullen

    2015-01-01

    Neural tissue engineering is premised on the integration of engineered living tissue with the host nervous system to directly restore lost function or to augment regenerative capacity following ner-vous system injury or neurodegenerative disease. Disconnection of axon pathways – the long-distance ifbers connecting specialized regions of the central nervous system or relaying peripheral signals – is a common feature of many neurological disorders and injury. However, functional axonal regenera-tion rarely occurs due to extreme distances to targets, absence of directed guidance, and the presence of inhibitory factors in the central nervous system, resulting in devastating effects on cognitive and sensorimotor function. To address this need, we are pursuing multiple strategies using tissue engi-neered “living scaffolds”, which are preformed three-dimensional constructs consisting of living neural cells in a deifned, often anisotropic architecture. Living scaffolds are designed to restore function by serving as a living labeled pathway for targeted axonal regeneration – mimicking key developmental mechanisms– or by restoring lost neural circuitry via direct replacement of neurons and axonal tracts. We are currently utilizing preformed living scaffolds consisting of neuronal clusters spanned by long axonal tracts as regenerative bridges to facilitate long-distance axonal regeneration and for targeted neurosurgical reconstruction of local circuits in the brain. Although there are formidable challenges in preclinical and clinical advancement, these living tissue engineered constructs represent a promising strategy to facilitate nervous system repair and functional recovery.

  11. Restoring nervous system structure and function using tissue engineered living scaffolds

    Directory of Open Access Journals (Sweden)

    Laura A Struzyna

    2015-01-01

    Full Text Available Neural tissue engineering is premised on the integration of engineered living tissue with the host nervous system to directly restore lost function or to augment regenerative capacity following nervous system injury or neurodegenerative disease. Disconnection of axon pathways - the long-distance fibers connecting specialized regions of the central nervous system or relaying peripheral signals - is a common feature of many neurological disorders and injury. However, functional axonal regeneration rarely occurs due to extreme distances to targets, absence of directed guidance, and the presence of inhibitory factors in the central nervous system, resulting in devastating effects on cognitive and sensorimotor function. To address this need, we are pursuing multiple strategies using tissue engineered "living scaffolds", which are preformed three-dimensional constructs consisting of living neural cells in a defined, often anisotropic architecture. Living scaffolds are designed to restore function by serving as a living labeled pathway for targeted axonal regeneration - mimicking key developmental mechanisms- or by restoring lost neural circuitry via direct replacement of neurons and axonal tracts. We are currently utilizing preformed living scaffolds consisting of neuronal clusters spanned by long axonal tracts as regenerative bridges to facilitate long-distance axonal regeneration and for targeted neurosurgical reconstruction of local circuits in the brain. Although there are formidable challenges in preclinical and clinical advancement, these living tissue engineered constructs represent a promising strategy to facilitate nervous system repair and functional recovery.

  12. Systems Biology of Immune Response to Live and Inactivated Dengue Virus Vaccines

    Science.gov (United States)

    2017-09-01

    AWARD NUMBER: W81XWH-16-2-0032 TITLE: Systems Biology of Immune Response to Live and Inactivated Dengue Virus Vaccines PRINCIPAL INVESTIGATOR...CONTRACT NUMBER Systems Biology of Immune Response to Live and Inactivated Dengue Virus Vaccines 5b. GRANT NUMBER W81XWH-16-2-0032 5c. PROGRAM ELEMENT...cell) responses will be measured using molecular and cellular approaches and the data analyzed using a systems biology approach. During the first

  13. Systems Biology of the Immune Response to Live and Inactivated Dengue Virus Vaccines

    Science.gov (United States)

    2017-09-01

    AWARD NUMBER: W81XWH-16-2-0031 TITLE: Systems Biology of the Immune Response to Live and Inactivated Dengue Virus Vaccines PRINCIPAL...SUBTITLE 5a. CONTRACT NUMBER Systems Biology of the Immune Response to Live and Inactivated Dengue Virus Vaccines 5b. GRANT NUMBER W81XWH-16-2-0031 5c...adaptive (T and B cell) responses will be measured using molecular and cellular approaches and the data analyzed using a systems biology approach

  14. A Simple FSPN Model of P2P Live Video Streaming System

    OpenAIRE

    Kotevski, Zoran; Mitrevski, Pece

    2011-01-01

    Peer to Peer (P2P) live streaming is relatively new paradigm that aims at streaming live video to large number of clients at low cost. Many such applications already exist in the market, but, prior to creating such system it is necessary to analyze its performance via representative model that can provide good insight in the system’s behavior. Modeling and performance analysis of P2P live video streaming systems is challenging task which requires addressing many properties and issues of P2P s...

  15. Live and Dead Nodes

    DEFF Research Database (Denmark)

    Jørgensen, Sune Lehman; Jackson, A. D.

    2005-01-01

    In this paper, we explore the consequences of a distinction between `live' and `dead' network nodes; `live' nodes are able to acquire new links whereas `dead' nodes are static. We develop an analytically soluble growing network model incorporating this distinction and show that it can provide...

  16. Assisted Living Systems for Elderly and Disabled People: A Short Review

    Directory of Open Access Journals (Sweden)

    Ivo Iliev

    2011-07-01

    Full Text Available The number of elderly people living alone in their homes is permanently growing in the whole western world. Because of the deteriorating capabilities to sense and interact with the environment, such as memory, eye sight, hearing and mobility, the ageing populations often live with significantly degraded life quality. Many also suffer from chronic diseases that require medical treatment and periodical examinations. Different Assisted Living Systems have been proposed to cope with the problems. The goal is to enable the elderly people to live longer in their preferred environment, to enhance the quality of their live and to reduce the expenses of the public health care. The Assisted Living Systems are based on a lot of sensors, actuators and multimedia equipment, providing for the autonomy of people and assisting them in carrying out their daily activities together with available interaction with remote relatives and friends. The applied approaches and implementations are specific that limit the dissemination of the results between the object oriented groups. Besides, most of the projects require considerable funding for implementation. For the time being and especially for some countries with lower Gross Domestic Product, the efforts may be directed to creation of low-cost assistive systems performing some basic tasks, related to the need and health status of the living alone adults or disabled people, e.g. automatic fall detection and signalization, as well as instantaneous monitoring the photo-pletismographic signals together with permanently available communication interface between the caregiver and the user.

  17. Live Fire Evaluation of the Expeditionary Fire Suppression System (EFSS); Phase I

    National Research Council Canada - National Science Library

    Kalberer, Jennifer

    2004-01-01

    .... The system uses AFFF-based compressed air foam and PKP dry chemical. Phase I evaluated the effectiveness of the modified-commercially available EFSS on live fires on static pool and running fuel fires...

  18. Geographic information system in marine biology: Way for sustainable utilization of living resources

    Digital Repository Service at National Institute of Oceanography (India)

    Chavan, V.S.; Sreepada, R.A.

    Sustainable utilization of aquatic living resources needs accurate assessment. This stress the need for use of Geographic Information System (GIS). In the recent past interest has been generated for use of GIS in various areas of biological...

  19. An Efficient Live TV Scheduling System for 4G LTE Broadcast

    KAUST Repository

    Lau, Chun Pong; Alabbasi, AbdulRahman; Shihada, Basem

    2016-01-01

    Traditional live television (TV) broadcasting systems are proven to be spectrum inefficient. Therefore, researchers propose to provide TV services on fourth-generation (4G) long-term evolution (LTE) networks. However, static broadcast, a typical

  20. Evaluating Living Standard Indicators

    Directory of Open Access Journals (Sweden)

    Birčiaková Naďa

    2015-09-01

    Full Text Available This paper deals with the evaluation of selected available indicators of living standards, divided into three groups, namely economic, environmental, and social. We have selected six countries of the European Union for analysis: Bulgaria, the Czech Republic, Hungary, Luxembourg, France, and Great Britain. The aim of this paper is to evaluate indicators measuring living standards and suggest the most important factors which should be included in the final measurement. We have tried to determine what factors influence each indicator and what factors affect living standards. We have chosen regression analysis as our main method. From the study of factors, we can deduce their impact on living standards, and thus the value of indicators of living standards. Indicators with a high degree of reliability include the following factors: size and density of population, health care and spending on education. Emissions of carbon dioxide in the atmosphere also have a certain lower degree of reliability.

  1. Living with others

    DEFF Research Database (Denmark)

    Zabiliute, Emilija

    Living with Others’ is an ethnographic study of everyday lives and health-seeking practices among urban poor living in a settlement in the margins of Delhi, India.By exploring subjectivities, lived experiences of poverty, and relations through a prism ofhealth, the inquiry aims to move beyond...... the explorations of precarity embedded in political economies and urban governance that dominate discussions on urban poor neighbourhoods in India.Empirically, the study draws on long-term ethnographic fieldwork and interviews among urban poor,mostly women;and formal and informal health practitioners, abundant...... in the area. Among these are governmental interventions,run under a maternal health developmental programme, National Rural Health Mission.The study argues that the vulnerabilities characterisingthe lives of the urban poor unfold and are negotiated through relations with kin, neighbours, and political patrons...

  2. Family self-tailoring: Applying a systems approach to improving family healthy living behaviors.

    Science.gov (United States)

    Moore, Shirley M; Jones, Lenette; Alemi, Farrokh

    2016-01-01

    The adoption and maintenance of healthy living behaviors by individuals and families is a major challenge. We describe a new model of health behavior change, SystemCHANGE (SC), which focuses on the redesign of family daily routines using system improvement methods. In the SC intervention, families are taught a set of skills to engage in a series of small, family self-designed experiments to test ideas to change their daily routines. The family system-oriented changes brought about by these experiments build healthy living behaviors into family daily routines so that these new behaviors happen as a matter of course, despite wavering motivation, willpower, or personal effort on the part of individuals. Case stories of the use of SC to improve family healthy living behaviors are provided. Results of several pilot tests of SC indicate its potential effectiveness to change health living behaviors across numerous populations. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Live weight and body measurements of male and female native ducks raised in different raising systems

    Directory of Open Access Journals (Sweden)

    Kadir Önk

    2018-05-01

    Full Text Available ABSTRACT The purpose of this study was to determine live weight and body measurements of male and female native ducks raised in different raising systems. One hundred and twenty native ducks (60 males, 60 females were used in the study. The ducks were raised in deep litter floor and cage systems. Live weight and body values were measured every two weeks, until they were 56 days old. Three-parameter logistic regression and Gompertz model were used to determine growth model of male and female ducks. Interactions of time-raising system and time-sex were statistically significant in terms of live weight. At the end of eight weeks, live weights of ducks raised in deep litter floor were higher than ducks raised in cage system. In addition, live weights of male ducks were higher than female ducks. Consequently, deep litter floor is more appropriate for live weight in native ducks. Accuracy rate of Three-parameter Logistic and Gompertz models for estimation of growth in ducks was between 0.91-0.95 and similar results were obtained from both models. The Gompertz model is appropriate for the data structure of this study because it contains fewer iterations than the Three-Parameter Logistic model.

  4. Interventions in everyday lives

    DEFF Research Database (Denmark)

    Dreier, Ole

    2015-01-01

    The purpose of psychotherapy is to help clients address and overcome problems troubling them in their everyday lives. Therapy can therefore only work if clients include it in their ongoing lives to deal with their problems. Detailed, systematic research is needed on how clients do so...... clients change their everyday lives to overcome their troubles. They also highlight what it involves for clients to accomplish this. It is concluded that we need more research on how to understand intervention; on the interaction between interventions and clients’ conduct of their everyday life...

  5. The critical roles of information and nonequilibrium thermodynamics in evolution of living systems.

    Science.gov (United States)

    Gatenby, Robert A; Frieden, B Roy

    2013-04-01

    Living cells are spatially bounded, low entropy systems that, although far from thermodynamic equilibrium, have persisted for billions of years. Schrödinger, Prigogine, and others explored the physical principles of living systems primarily in terms of the thermodynamics of order, energy, and entropy. This provided valuable insights, but not a comprehensive model. We propose the first principles of living systems must include: (1) Information dynamics, which permits conversion of energy to order through synthesis of specific and reproducible, structurally-ordered components; and (2) Nonequilibrium thermodynamics, which generate Darwinian forces that optimize the system.Living systems are fundamentally unstable because they exist far from thermodynamic equilibrium, but this apparently precarious state allows critical response that includes: (1) Feedback so that loss of order due to environmental perturbations generate information that initiates a corresponding response to restore baseline state. (2) Death due to a return to thermodynamic equilibrium to rapidly eliminate systems that cannot maintain order in local conditions. (3) Mitosis that rewards very successful systems, even when they attain order that is too high to be sustainable by environmental energy, by dividing so that each daughter cell has a much smaller energy requirement. Thus, nonequilibrium thermodynamics are ultimately responsible for Darwinian forces that optimize system dynamics, conferring robustness sufficient to allow continuous existence of living systems over billions of years.

  6. Living with COPD: Nutrition

    Science.gov (United States)

    ... Diseases > Lung Disease Lookup > COPD > Living With COPD Nutrition and COPD Most people are surprised to learn ... asking your doctor or visiting the Academy of Nutrition and Dietetics at EatRight.org . Be sure to ...

  7. Living Day by Day

    Science.gov (United States)

    Kaplan, Rachel L.; Khoury, Cynthia El; Field, Emily R. S.; Mokhbat, Jacques

    2016-01-01

    We examined the meaning of living with HIV/AIDS among women in Lebanon. Ten women living with HIV/AIDS (WLWHA) described their experiences via semistructured in-depth interviews. They navigated a process of HIV diagnosis acceptance that incorporated six overlapping elements: receiving the news, accessing care, starting treatment, navigating disclosure decisions, negotiating stigma, and maintaining stability. Through these elements, we provide a framework for understanding three major themes that were constructed during data analysis: Stand by my side: Decisions of disclosure; Being “sick” and feeling “normal”: Interacting with self, others, and society; and Living day by day: focusing on the present. We contribute to the existing literature by providing a theoretical framework for understanding the process of diagnosis and sero-status acceptance among WLWHA. This was the first study of its kind to examine the meaning of living with HIV/AIDS among women in a Middle Eastern country. PMID:28462340

  8. Living Day by Day

    Directory of Open Access Journals (Sweden)

    Rachel L. Kaplan

    2016-05-01

    Full Text Available We examined the meaning of living with HIV/AIDS among women in Lebanon. Ten women living with HIV/AIDS (WLWHA described their experiences via semistructured in-depth interviews. They navigated a process of HIV diagnosis acceptance that incorporated six overlapping elements: receiving the news, accessing care, starting treatment, navigating disclosure decisions, negotiating stigma, and maintaining stability. Through these elements, we provide a framework for understanding three major themes that were constructed during data analysis: Stand by my side: Decisions of disclosure; Being “sick” and feeling “normal”: Interacting with self, others, and society; and Living day by day: focusing on the present. We contribute to the existing literature by providing a theoretical framework for understanding the process of diagnosis and sero-status acceptance among WLWHA. This was the first study of its kind to examine the meaning of living with HIV/AIDS among women in a Middle Eastern country.

  9. Living With Diabetes

    Science.gov (United States)

    ... Problems Diabetes, Sexual, & Bladder Problems Clinical Trials Managing Diabetes You can manage your diabetes and live a ... you have diabetes. How can I manage my diabetes? With the help of your health care team, ...

  10. Thalassemia: Healthy Living

    Science.gov (United States)

    ... Thalassemia” More What can a person living with thalassemia do to stay healthy? A healthy lifestyle is ... disorder”, as well as making healthy choices. Managing Thalassemia Thalassemia is a treatable disorder that can be ...

  11. Writing lives in sport

    DEFF Research Database (Denmark)

    Christensen, Mette Krogh

    dealing with anonymous individuals, whose anonymity results from the confidentiality requirements of a social scientific research methodology, to those leaning more towards the literary-historical traditions of 'conventional' biographical writing. However, these examples are polar extremes and none...... in the academis world of sport studies. It does not set out to be a methodological treatise but through the writing of lives in sports does raise questions of method. Each essay in this collection deals with problems of writing sports-people's lives. These essays could be said to fall along a spectrum from those......Writing lives in sport is a book of stories about sports-persons. The people concerned include sports stars, sports people who are not quite so famous, and relatively unknown physical education teachers and sports scientists.Writing lives in sport raises questions about writing biographies...

  12. Living with Tuberculosis

    Science.gov (United States)

    ... Diseases > Lung Disease Lookup > Tuberculosis (TB) Living With Tuberculosis What to Expect You will need regular checkups ... XML file."); } }); } } --> Blank Section Header Lung Disease Lookup Tuberculosis (TB) Learn About Tuberculosis Tuberculosis Symptoms, Causes & Risk ...

  13. Tips for Daily Living

    Science.gov (United States)

    ... Simple Techniques Can Help Memory after a Stroke Self-Esteem after Stroke Cognitive Challenges After Stroke Depression Trumps ... Living Driving Finding Support You Are Not Alone Online Support Recovery and Support after Stroke Stroke Family ...

  14. Our Urban Living Room

    DEFF Research Database (Denmark)

    Hjortshøj, Rasmus

    2016-01-01

    Our Urban Living Room is an exhibition and a book, created by Cobe. The theme is based on Cobe’s ten years of practice, grounded in social livability and urban democracy, and our aim to create buildings and spaces that invite Copenhageners to use and define them; as an extended living room, where...... the boundaries between private and public space become fluid. Based on specific Cobe projects, Our Urban Living Room tells stories about the architectural development of Copenhagen, while exploring the progression of the Danish Capital - from an industrial city into an urban living room, known as one...... of the world’s most livable places. Photography by Rasmus Hjortshøj....

  15. Biometric Authentication Systems Attacks: Liveness Detection to the ...

    African Journals Online (AJOL)

    AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING AJOL · RESOURCES ... access control, sensitive data protection and on-line tracking systems. ... This paper has identified such vulnerabilities and threats, particularly ... Systems, Authentication, Verification, Vulnerabilities, attacks, Threats.

  16. Safe and Automatic Live Update for Operating Systems

    NARCIS (Netherlands)

    Giuffrida, C.; Kuijsten, A.; Tanenbaum, A.S.

    2013-01-01

    Increasingly many systems have to run all the time with no downtime allowed. Consider, for example, systems controlling electric power plants and e-banking servers. Nevertheless, security patches and a constant stream of new operating system versions need to be deployed without stopping running

  17. Emergency Systems Save Tens of Thousands of Lives

    Science.gov (United States)

    2013-01-01

    To improve distress signal communications, NASA pioneered the Search and Rescue Satellite Aided Tracking (SARSAT) system. Since its inception, the international system known as Cospas-Sarsat has resulted in the rescue of more than 30,000 people. Techno-Sciences Inc., of Beltsville, Maryland, has been involved with the ground station component of the system from its earliest days.

  18. A living PSA based on use of expert systems

    International Nuclear Information System (INIS)

    Ancelin, C.; Bouissou, M.; Le, P.; De Saint-Quentin, S.; Villatte, N.

    1989-01-01

    This paper presents the expert systems that are developed by EDF in the framework of the French PSA. Aimed at automatically generating reliability models (fault trees, state graphs....), these expert systems are used for the reliability studies of safety systems in the Paluel nuclear power plant. Beyond the description of the implemented method, this paper insists on the new approach proposed to the reliability engineer, when using artificial intelligence techniques

  19. Improving lives through a bioartificial liver support system

    CSIR Research Space (South Africa)

    Naidoo, K

    2008-11-01

    Full Text Available This poster covers the development of a technology towards a novel bioartificial liver support system (BALSS) that is capable of providing liver functions, in patients with acute liver failure, while housed outside the body (extra corporeal...

  20. Biometric Authentication Systems Attacks: Liveness Detection to the ...

    African Journals Online (AJOL)

    PROF. OLIVER OSUAGWA

    2014-12-01

    Dec 1, 2014 ... 1Department of Computer Science, Imo State University, Owerri ... potential to provide security for a variety of applications. BAS are nowadays ... access control, sensitive data protection and on-line tracking systems. Like any ...

  1. Systems and operations - Living with complexity and growth

    Science.gov (United States)

    Hook, W. R.

    1983-03-01

    Since the space station concept currently being developed by NASA calls for system updates and additions over a period of at least ten years following launch, attention must be given to the interfaces between station elements. Efforts have begun to develop generic fault detection, isolation, and correction techniques that could simplify on-orbit operations, maintenance and repair. An integrated hydrogen-oxygen system has been identified as the feature promising the greatest reduction in resupply costs. Scavenging excess fuel from the Space Shuttle's internal and external tanks, and using leftover Shuttle payload for fluid tankage, could supply hydrogen and oxygen for consumption in the form of propellants, fuel cell electricity, and life support gases. Advancements in cryogenic fluid management and storage technology are the keys to the design of this integrated system. Attention is given to the Interactive Design and Evaluation of Advanced Spacecraft computer-aided design and analysis system, which allows system engineers to study the integration problems presented by 40 technical modules.

  2. Can lean save lives?

    Science.gov (United States)

    Fillingham, David

    2007-01-01

    The purpose of this paper is to show how over the last 18 months Bolton Hospitals NHS Trust have been exploring whether or not lean methodologies, often known as the Toyota Production System, can indeed be applied to healthcare. This paper is a viewpoint. One's early experience is that lean really can save lives. The Toyota Production System is an amazingly successful way of manufacturing cars. It cannot be simply translated unthinkingly into a hospital but lessons can be learned from it and the method can be adapted and developed so that it becomes owned by healthcare staff and focused towards the goal of improved patient care. Working in healthcare is a stressful and difficult thing. Everyone needs a touch of inspiration and encouragement. Applying lean to healthcare in Bolton seems to be achieving just that for those who work there.

  3. System Thinking and Feeding Relations: Learning with a Live Ecosystem Model

    Science.gov (United States)

    Eilam, Billie

    2012-01-01

    Considering well-documented difficulties in mastering ecology concepts and system thinking, the aim of the study was to examine 9th graders' understanding of the complex, multilevel, systemic construct of feeding relations, nested within a larger system of a live model. Fifty students interacted with the model and manipulated a variable within it…

  4. Living among giants exploring and settling the outer solar system

    CERN Document Server

    Carroll, Michael

    2015-01-01

    The outer Solar System is rich in resources and may be the best region in which to search for life beyond Earth. In fact, it may ultimately be the best place for Earthlings to set up permanent abodes. This book surveys the feasibility of that prospect, covering the fascinating history of exploration that kicks off our adventure into the outer Solar System.   Although other books provide surveys of the outer planets, Carroll approaches it from the perspective of potential future human exploration, exploitation and settlement, using insights from today’s leading scientists in the field. These experts take us to targets such as the moons Titan, Triton, Enceladus, Iapetus and Europa, and within the atmospheres of the gas and ice giants. In these pages you will experience the thrill of discovery awaiting those who journey through the giant worlds and their moons.   All the latest research is included, as are numerous illustrations, among them original paintings by the author, a renowned prize-winning space art...

  5. Housing First and Photovoice: Transforming Lives, Communities, and Systems

    Science.gov (United States)

    Barile, John P.; Ogawa, Terry Yasuko; Peralta, Nelson; Bugg, Reumell; Lau, John; Lamberton, Thomas; Hall, Corazon; Mori, Victor

    2018-01-01

    This article presents findings from a community-based participatory evaluation of a Housing First program on the Island of O’ahu. In this study, clients in a Housing First program used Photovoice to evaluate the program and to advocate for progressive housing policies. Written together by members of the Housing First Photovoice group, this collaborative article describes the outcomes from both the Housing First program and the Photovoice project and demonstrates the ways in which participatory program evaluations can interact with client-driven programs like Housing First to produce a cumulative, transformative impact. Findings suggest that community psychologists hoping to re-engage with community mental health systems through enacting transformative change should consider taking a community-based participatory approach to program evaluation because increased client voice in community mental health programs and their evaluations can have far-reaching, transformative impacts for research, practice, and policy. PMID:29323410

  6. Functional fusion of living systems with synthetic electrode interfaces

    Directory of Open Access Journals (Sweden)

    Oskar Staufer

    2016-02-01

    Full Text Available The functional fusion of “living” biomaterial (such as cells with synthetic systems has developed into a principal ambition for various scientific disciplines. In particular, emerging fields such as bionics and nanomedicine integrate advanced nanomaterials with biomolecules, cells and organisms in order to develop novel strategies for applications, including energy production or real-time diagnostics utilizing biomolecular machineries “perfected” during billion years of evolution. To date, hardware–wetware interfaces that sample or modulate bioelectric potentials, such as neuroprostheses or implantable energy harvesters, are mostly based on microelectrodes brought into the closest possible contact with the targeted cells. Recently, the possibility of using electrochemical gradients of the inner ear for technical applications was demonstrated using implanted electrodes, where 1.12 nW of electrical power was harvested from the guinea pig endocochlear potential for up to 5 h (Mercier, P.; Lysaght, A.; Bandyopadhyay, S.; Chandrakasan, A.; Stankovic, K. Nat. Biotech. 2012, 30, 1240–1243. More recent approaches employ nanowires (NWs able to penetrate the cellular membrane and to record extra- and intracellular electrical signals, in some cases with subcellular resolution (Spira, M.; Hai, A. Nat. Nano. 2013, 8, 83–94. Such techniques include nanoelectric scaffolds containing free-standing silicon NWs (Robinson, J. T.; Jorgolli, M.; Shalek, A. K.; Yoon, M. H.; Gertner, R. S.; Park, H. Nat Nanotechnol. 2012, 10, 180–184 or NW field-effect transistors (Qing, Q.; Jiang, Z.; Xu, L.; Gao, R.; Mai, L.; Lieber, C. Nat. Nano. 2013, 9, 142–147, vertically aligned gallium phosphide NWs (Hällström, W.; Mårtensson, T.; Prinz, C.; Gustavsson, P.; Montelius, L.; Samuelson, L.; Kanje, M. Nano Lett. 2007, 7, 2960–2965 or individually contacted, electrically active carbon nanofibers. The latter of these approaches is capable of recording

  7. TAX SYSTEM FOR MEMBERS OF THE PERSONNEL LIVING IN FRANCE

    CERN Document Server

    Human Resources Division

    2002-01-01

    - Declaration of income for 2001 - This text is also available on the Human Resources Division website. Important The French tax authorities have informed the Organization of certain changes to the tax system applicable to certain members of the CERN personnel residing in France. The CERN Management is currently seeking to clarify a number of points relating to the application of these measures. For the moment, members of the personnel residing in France are requested to follow the instructions outlined below and any other related instructions published later in 2002. To deal with the increasing number of requests for personal advice, the Human Resources Division has set up a Help-Desk, on 72838 (*), which will direct you to the relevant in-house or outside services. However, as the Human Resources Division cannot speak for the tax authorities and does not have the necessary resources to handle all the problems that are referred to it, members of the personnel are strongly urged to contact the Fren...

  8. Supporting peace of mind and independent living with the Aurama awareness system

    NARCIS (Netherlands)

    Dadlani Mahtani, Pavan; Markopoulos, P.; Sinitsyn, A.G.; Aarts, E.H.L.

    2011-01-01

    An awareness system was designed to provide peace of mind and a sense of connectedness to adults who care for an elderly parent living alone. The iterative design of the Aurama awareness system showed and our empirical research, including field trials ranging from four to six months, confirm the

  9. Supporting peace of mind and independent living with the Aurama awareness system

    NARCIS (Netherlands)

    Dadlani Mahtani, P.; Markopoulos, P.; Sinitsyn, A.G.; Aarts, E.H.L.

    2011-01-01

    An awareness system was designed to provide peace of mind and a sense of connectedness to adults who care for an elderly parent living alone. The iterative design of the Aurama awareness system showed andour empirical research, including field trials ranging from four tosix months, confirm the

  10. Influence of the environment and phototoxicity of the live cell imaging system at IMP microbeam facility

    Science.gov (United States)

    Liu, Wenjing; Du, Guanghua; Guo, Jinlong; Wu, Ruqun; Wei, Junzhe; Chen, Hao; Li, Yaning; Zhao, Jing; Li, Xiaoyue

    2017-08-01

    To investigate the spatiotemporal dynamics of DNA damage and repair after the ion irradiation, an online live cell imaging system has been established based on the microbeam facility at Institute of Modern Physics (IMP). The system could provide a sterile and physiological environment by making use of heating plate and live cell imaging solution. The phototoxicity was investigated through the evaluation of DNA repair protein XRCC1 foci formed in HT1080-RFP cells during the imaging exposure. The intensity of the foci induced by phototoxicity was much lower compared with that of the foci induced by heavy ion hits. The results showed that although spontaneous foci were formed due to RFP exposure during live cell imaging, they had little impact on the analysis of the recruitment kinetics of XRCC1 in the foci induced by the ion irradiation.

  11. Image acquisition optimization of a limited-angle intrafraction verification (LIVE) system for lung radiotherapy.

    Science.gov (United States)

    Zhang, Yawei; Deng, Xinchen; Yin, Fang-Fang; Ren, Lei

    2018-01-01

    Limited-angle intrafraction verification (LIVE) has been previously developed for four-dimensional (4D) intrafraction target verification either during arc delivery or between three-dimensional (3D)/IMRT beams. Preliminary studies showed that LIVE can accurately estimate the target volume using kV/MV projections acquired over orthogonal view 30° scan angles. Currently, the LIVE imaging acquisition requires slow gantry rotation and is not clinically optimized. The goal of this study is to optimize the image acquisition parameters of LIVE for different patient respiratory periods and gantry rotation speeds for the effective clinical implementation of the system. Limited-angle intrafraction verification imaging acquisition was optimized using a digital anthropomorphic phantom (XCAT) with simulated respiratory periods varying from 3 s to 6 s and gantry rotation speeds varying from 1°/s to 6°/s. LIVE scanning time was optimized by minimizing the number of respiratory cycles needed for the four-dimensional scan, and imaging dose was optimized by minimizing the number of kV and MV projections needed for four-dimensional estimation. The estimation accuracy was evaluated by calculating both the center-of-mass-shift (COMS) and three-dimensional volume-percentage-difference (VPD) between the tumor in estimated images and the ground truth images. The robustness of LIVE was evaluated with varied respiratory patterns, tumor sizes, and tumor locations in XCAT simulation. A dynamic thoracic phantom (CIRS) was used to further validate the optimized imaging schemes from XCAT study with changes of respiratory patterns, tumor sizes, and imaging scanning directions. Respiratory periods, gantry rotation speeds, number of respiratory cycles scanned and number of kV/MV projections acquired were all positively correlated with the estimation accuracy of LIVE. Faster gantry rotation speed or longer respiratory period allowed less respiratory cycles to be scanned and less kV/MV projections

  12. Living with HIV

    Science.gov (United States)

    ... Abroad Treatment Basic Statistics Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... Syndicated Content Website Feedback HIV/AIDS Living With HIV Language: English (US) Español (Spanish) Recommend on Facebook ...

  13. Adults Living with OI

    Science.gov (United States)

    ... Wheel Regional Conference 50,000 Laps, One Unbreakable Spirit® OI Golf Classic Awareness Week Fine Wines Strong Bones Bone China Tea Blue Jeans for Better Bones Upcoming Events Online Store Adults Living with OI Write to us with your suggestions for what we should include on this page; your input ...

  14. Readiness for Living Technology

    DEFF Research Database (Denmark)

    Peronard, Jean-Paul

    2013-01-01

    This paper is a comparative analysis between workers in healthcare with high and low degree of readiness for living technology such as robotics. To explore the differences among workers’ readiness for robotics in healthcare, statistical analysis was conducted in the data set obtained from 200...

  15. Live-cell imaging.

    Science.gov (United States)

    Cole, Richard

    2014-01-01

    It would be hard to argue that live-cell imaging has not changed our view of biology. The past 10 years have seen an explosion of interest in imaging cellular processes, down to the molecular level. There are now many advanced techniques being applied to live cell imaging. However, cellular health is often under appreciated. For many researchers, if the cell at the end of the experiment has not gone into apoptosis or is blebbed beyond recognition, than all is well. This is simply incorrect. There are many factors that need to be considered when performing live-cell imaging in order to maintain cellular health such as: imaging modality, media, temperature, humidity, PH, osmolality, and photon dose. The wavelength of illuminating light, and the total photon dose that the cells are exposed to, comprise two of the most important and controllable parameters of live-cell imaging. The lowest photon dose that achieves a measureable metric for the experimental question should be used, not the dose that produces cover photo quality images. This is paramount to ensure that the cellular processes being investigated are in their in vitro state and not shifted to an alternate pathway due to environmental stress. The timing of the mitosis is an ideal canary in the gold mine, in that any stress induced from the imaging will result in the increased length of mitosis, thus providing a control model for the current imagining conditions.

  16. Living or Nonliving?

    Science.gov (United States)

    Legaspi, Britt; Straits, William

    2011-01-01

    Categorizing organisms as living or nonliving things may seem to be intuitive by nature. Yet, it is regulated by scientific criteria. Students come to school with rules already in place. Their categorizing criteria have already been influenced by their personal experiences, also known as observations and inferences. They believe that all things…

  17. Living with Light

    DEFF Research Database (Denmark)

    Nielsen, Stine Maria Louring; Mullins, Michael Finbarr

    2018-01-01

    in their daily lives. It is argued that these patterns are largely shaped by the elderly’s bodily, social and cultural experiences and contexts, so a framework encompassing four major themes is proposed: 1. Traditions, Economy and Environment; 2. Quality of Life and Independence; 3. Health; and 4. Security...

  18. The Living Periodic Table

    Science.gov (United States)

    Nahlik, Mary Schrodt

    2005-01-01

    To help make the abstract world of chemistry more concrete eighth-grade students, the author has them create a living periodic table that can be displayed in the classroom or hallway. This display includes information about the elements arranged in the traditional periodic table format, but also includes visual real-world representations of the…

  19. Gun control saves lives

    African Journals Online (AJOL)

    gun control legislation. One study estimated that more than 4 500 lives were saved across five SA cities from 2001 to 2005.[5] Pro-gun interest groups seeking to promote gun ownership and diffusion have attacked these findings, suggesting that stricter gun control was only enacted in 2004 following the publication of ...

  20. Old men living alone

    DEFF Research Database (Denmark)

    Hansen, Kristian Frausing; Munk, Karen Pallesgaard

    . 1. An electronic survey is distributed nationwide to municipal preventive home visitors in order to obtain information about their views on the men’s particular needs and the suitability of current health care services. 2. A group of elderly men living alone is interviewed about their own opinions...

  1. Creating living machines

    Science.gov (United States)

    Kamm, Roger D.; Bashir, Rashid

    2015-01-01

    Development of increasingly complex integrated cellular systems will be a major challenge for the next decade and beyond, as we apply the knowledge gained from the sub-disciplines of tissue engineering, synthetic biology, micro-fabrication and nanotechnology, systems biology, and developmental biology. In this prospective, we describe the current state-of-the-art in the context of differentiating source cells from more primitive, pluripotent cells, and organizing these cells into populations of a single cell type to produce the components or building blocks of higher order systems and finally, combining multiple cell types, possibly in combination with scaffolds possessing specific physical or chemical properties, to produce greater functionality. As these “living machines” increase in capabilities, exhibit emergent behavior and potentially reveal the ability for self-assembly, self-repair, and even self-replication, questions arise regarding the ethical implications of this work. Future prospects as well as ways of addressing these complex ethical questions will be addressed. PMID:24006130

  2. A future of living machines?: International trends and prospects in biomimetic and biohybrid systems

    Science.gov (United States)

    Prescott, Tony J.; Lepora, Nathan; Vershure, Paul F. M. J.

    2014-03-01

    Research in the fields of biomimetic and biohybrid systems is developing at an accelerating rate. Biomimetics can be understood as the development of new technologies using principles abstracted from the study of biological systems, however, biomimetics can also be viewed from an alternate perspective as an important methodology for improving our understanding of the world we live in and of ourselves as biological organisms. A biohybrid entity comprises at least one artificial (engineered) component combined with a biological one. With technologies such as microscale mobile computing, prosthetics and implants, humankind is moving towards a more biohybrid future in which biomimetics helps us to engineer biocompatible technologies. This paper reviews recent progress in the development of biomimetic and biohybrid systems focusing particularly on technologies that emulate living organisms—living machines. Based on our recent bibliographic analysis [1] we examine how biomimetics is already creating life-like robots and identify some key unresolved challenges that constitute bottlenecks for the field. Drawing on our recent research in biomimetic mammalian robots, including humanoids, we review the future prospects for such machines and consider some of their likely impacts on society, including the existential risk of creating artifacts with significant autonomy that could come to match or exceed humankind in intelligence. We conclude that living machines are more likely to be a benefit than a threat but that we should also ensure that progress in biomimetics and biohybrid systems is made with broad societal consent.

  3. From Living Space to Cultural Space: How a Modern University Academy System Is Possible

    Science.gov (United States)

    Zhang, Yingqiang; Fang, Hualiang

    2018-01-01

    The reforms on the modern university academy system that preserve certain elements of China's ancient traditional academies have currently encountered a series of difficulties. The crux of the problem is that living and educational spaces were integrated in the traditional academy, while modern school education institution has separated the two.…

  4. Being a Living Donor: Risks

    Science.gov (United States)

    ... to know FAQ Living donation What is living donation? Organs Types Being a living donor First steps Being ... are considering one of these types of living donation, please talk to your transplant center about the organ-specific risks. Psychological concerns You may also have ...

  5. Physics of Life: A Model for Non-Newtonian Properties of Living Systems

    Science.gov (United States)

    Zak, Michail

    2010-01-01

    This innovation proposes the reconciliation of the evolution of life with the second law of thermodynamics via the introduction of the First Principle for modeling behavior of living systems. The structure of the model is quantum-inspired: it acquires the topology of the Madelung equation in which the quantum potential is replaced with the information potential. As a result, the model captures the most fundamental property of life: the progressive evolution; i.e. the ability to evolve from disorder to order without any external interference. The mathematical structure of the model can be obtained from the Newtonian equations of motion (representing the motor dynamics) coupled with the corresponding Liouville equation (representing the mental dynamics) via information forces. All these specific non-Newtonian properties equip the model with the levels of complexity that matches the complexity of life, and that makes the model applicable for description of behaviors of ecological, social, and economical systems. Rather than addressing the six aspects of life (organization, metabolism, growth, adaptation, response to stimuli, and reproduction), this work focuses only on biosignature ; i.e. the mechanical invariants of life, and in particular, the geometry and kinematics of behavior of living things. Living things obey the First Principles of Newtonian mechanics. One main objective of this model is to extend the First Principles of classical physics to include phenomenological behavior on living systems; to develop a new mathematical formalism within the framework of classical dynamics that would allow one to capture the specific properties of natural or artificial living systems such as formation of the collective mind based upon abstract images of the selves and non-selves; exploitation of this collective mind for communications and predictions of future expected characteristics of evolution; and for making decisions and implementing the corresponding corrections if

  6. Live videotransmitteret undervisning

    Directory of Open Access Journals (Sweden)

    Rikke Ørngreen

    2013-11-01

    På Bioanalytikeruddannelsen i Aarhus, VIAs sundhedsfaglige højskole, har man i en længere periode haft et kombi-hold, hvor man kombinerer traditionel og live transmitteret undervisning (via et innovativt valg af videokonferencesystem. På de såkaldte netdage er der mulighed for enten at møde op til undervisningen, som man plejer, eller at deltage i undervisningen hjemmefra. Artiklen præsenterer et deltagende aktionsforskningsprojekt mellem projektteamet på udannelsen og forskere fra Aalborg Universitet. Målet var at: afdække potentialer og barrierer ud fra et it-støttet læringsperspektiv; udvikle robuste didaktiske undervisningsscenarier; samt kvalificere underviserne og hermed forankringen af projektet. Forskningsdata blev indsamlet gennem videooptagelser, ”dagens spørgsmål” til de studerende, fokusgruppeinterview med lærerne, og Pædagogisk Dag-workshop. Analysen sætter fokus på erfaringerne under anvendelse af professionshøjskolernes Rektorkollegiums Studieaktivitetsmodel. Slutteligt samles der i artiklen op på de teknologsike, sociale og didaktiske-pædagogiske relationer set i lyset af projektets mål og resultater. Abstract in English At the education for Biomedical Laboratory Scientist at Aarhus, VIA's healthcare college, they have a combi-class, combining traditional and live broadcast teaching (via an innovative choice of video conferencing system. In the so-called net-days, there is the option to either attend the classes as usual, or to attend classes from home. This paper presents a participatory action research project between the project team at VIA and researchers from Aalborg University. The objectives were to: identify potentials and barriers from an IT-supported learning perspective; develop robust didactic teaching scenarios; qualify teachers, and secure the anchoring of the project. Research data were collected through video recordings, "questions of the day" to the students, focus group interviews with teachers and

  7. Living in history

    DEFF Research Database (Denmark)

    Brown, Norman R.; Lee, Peter J.; Krslak, Mirna

    2009-01-01

    Foreslår et paradigme - "Living in history" - til undersøgelse af forholdet mellem samtidshistorie og selvbiografisk hukommelse. Metoden spørger ikke direkte og altså ikke til den anknytning, man bevidst ville vælge at fremhæve, men undersøger indirekte, om der spontant associeres til samtidsbegi......Foreslår et paradigme - "Living in history" - til undersøgelse af forholdet mellem samtidshistorie og selvbiografisk hukommelse. Metoden spørger ikke direkte og altså ikke til den anknytning, man bevidst ville vælge at fremhæve, men undersøger indirekte, om der spontant associeres til...

  8. More Years Better Lives

    DEFF Research Database (Denmark)

    Fristrup, Tine

    2014-01-01

    Europe and the rest of the world, which may help offset the effects of ageing in some counties or regions, but which brings its own challenges. Alongside this change in the structure of the population, we are seeing a reshaping of the lifecourse, from a fairly simple one with three stages – childhood...... and assistive technologies are enabling people to live longer and healthier lives, but sometimes at a substantial cost. Communication technologies are transforming how people interact, how business is done and how public services are delivered. These changes have positive and negative dimensions and can present......Demographic change is changing the shape of Europe. Rising life expectancy, combined with low fertility rates and complex patterns of migration, mean that while the size of the population remains stable, its distribution and average age is rising steadily. At the same time general health...

  9. Living the (codesign) lab

    DEFF Research Database (Denmark)

    Binder, Thomas; Brandt, Eva; Halse, Joachim

    2011-01-01

    Design research environments are becoming visible in many places, in universities, in design schools, in companies and in public organizations. What most of them have in common is a commitment to the exploration of the possible rather than the factual. In this paper we will discuss what define su...... that the laboratories of design research must have a consistent portfolio yet design researchers still have to mobilize and join forces with the many “living labs” of the everyday....

  10. [Living kidney donation].

    Science.gov (United States)

    Timsit, M-O; Kleinclauss, F; Mamzer Bruneel, M F; Thuret, R

    2016-11-01

    To review ethical, legal and technical aspects of living kidney donor surgery. An exhaustive systematic review of the scientific literature was performed in the Medline database (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com) using different associations of the following keywords: Donor nephrectomy; Kidney paired donation; Kidney transplantation; Laparoscopic nephrectomy; Living donor; Organs trafficking; Robotic assisted nephrectomy; Vaginal extraction. French legal documents have been reviewed using the government portal (http://www.legifrance.gouv.fr). Articles were selected according to methods, language of publication and relevance. A total of 6421 articles were identified; after careful selection, 161 publications were considered of interest and were eligible for our review. The ethical debate focuses on organ shortage, financial incentive, organ trafficking and the recent data suggesting a small but significant increase risk for late renal disease in donor population. Legal decisions aim to increase the number of kidneys available for donation, such as kidney-paired donation that faces several obstacles in France. Laparoscopic approach became widely used, while robotic-assisted donor nephrectomy failed to demonstrate improved outcome as compared with other minimal invasive techniques. Minimally invasive living donor nephrectomy aims to limit side effects in the donor without increasing the morbidity in this specific population of healthy persons; long term surveillance to prevent the onset of renal disease in mandatory. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  11. Canada: Living with radiation

    International Nuclear Information System (INIS)

    1995-01-01

    Canadians are exposed daily to a variety of naturally occurring radiation. Heat and light from the sun, are familiar examples. Radium and uranium are naturally occurring materials which have been found to emit radiation and so have been called radioactive. There are also various types of artificially produced forms of radiation that are employed routinely in modern living, such as radio and television waves and microwaves. X-rays, another common type of radiation, are widely used in medicine as are some man-made radioactive substances. These emit radiation just like naturally occurring radioactive materials. Surveys have shown that many people have a poor understanding of the risks associated with the activities of modern living. Exposure to ionizing radiation from radioactive materials is also considered by many persons to have a high risk, This booklet attempts to inform the readers about ionizing radiation, its uses and the risks associated with it, and to put these risks in perspective with the risks of other activities and practices. A range of topics from medical uses of radiation to emergency planning, from biological effects of radiation to nuclear power, each topic is explained to relate radiation to our everyday lives. 44 figs

  12. Canada: Living with radiation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    Canadians are exposed daily to a variety of naturally occurring radiation. Heat and light from the sun, are familiar examples. Radium and uranium are naturally occurring materials which have been found to emit radiation and so have been called radioactive. There are also various types of artificially produced forms of radiation that are employed routinely in modern living, such as radio and television waves and microwaves. X-rays, another common type of radiation, are widely used in medicine as are some man-made radioactive substances. These emit radiation just like naturally occurring radioactive materials. Surveys have shown that many people have a poor understanding of the risks associated with the activities of modern living. Exposure to ionizing radiation from radioactive materials is also considered by many persons to have a high risk, This booklet attempts to inform the readers about ionizing radiation, its uses and the risks associated with it, and to put these risks in perspective with the risks of other activities and practices. A range of topics from medical uses of radiation to emergency planning, from biological effects of radiation to nuclear power, each topic is explained to relate radiation to our everyday lives. 44 figs.

  13. The S-Lagrangian and a theory of homeostasis in living systems

    Science.gov (United States)

    Sandler, U.; Tsitolovsky, L.

    2017-04-01

    A major paradox of living things is their ability to actively counteract degradation in a continuously changing environment or being injured through homeostatic protection. In this study, we propose a dynamic theory of homeostasis based on a generalized Lagrangian approach (S-Lagrangian), which can be equally applied to physical and nonphysical systems. Following discoverer of homeostasis Cannon (1935), we assume that homeostasis results from tendency of the organisms to decrease of the stress and avoid of death. We show that the universality of homeostasis is a consequence of analytical properties of the S-Lagrangian, while peculiarities of the biochemical and physiological mechanisms of homeostasis determine phenomenological parameters of the S-Lagrangian. Additionally, we reveal that plausible assumptions about S-Lagrangian features lead to good agreement between theoretical descriptions and observed homeostatic behavior. Here, we have focused on homeostasis of living systems, however, the proposed theory is also capable of being extended to social systems.

  14. A new course and textbook on Physical Models of Living Systems, for science and engineering undergraduates

    Science.gov (United States)

    Nelson, Philip

    2015-03-01

    I'll describe an intermediate-level course on ``Physical Models of Living Systems.'' The only prerequisite is first-year university physics and calculus. The course is a response to rapidly growing interest among undergraduates in a broad range of science and engineering majors. Students acquire several research skills that are often not addressed in traditional courses: Basic modeling skills Probabilistic modeling skills Data analysis methods Computer programming using a general-purpose platform like MATLAB or Python Dynamical systems, particularly feedback control. These basic skills, which are relevant to nearly any field of science or engineering, are presented in the context of case studies from living systems, including: Virus dynamics Bacterial genetics and evolution of drug resistance Statistical inference Superresolution microscopy Synthetic biology Naturally evolved cellular circuits. Work supported by NSF Grants EF-0928048 and DMR-0832802.

  15. An undergraduate course, and new textbook, on ``Physical Models of Living Systems''

    Science.gov (United States)

    Nelson, Philip

    2015-03-01

    I'll describe an intermediate-level course on ``Physical Models of Living Systems.'' The only prerequisite is first-year university physics and calculus. The course is a response to rapidly growing interest among undergraduates in several science and engineering departments. Students acquire several research skills that are often not addressed in traditional courses, including: basic modeling skills, probabilistic modeling skills, data analysis methods, computer programming using a general-purpose platform like MATLAB or Python, dynamical systems, particularly feedback control. These basic skills, which are relevant to nearly any field of science or engineering, are presented in the context of case studies from living systems, including: virus dynamics; bacterial genetics and evolution of drug resistance; statistical inference; superresolution microscopy; synthetic biology; naturally evolved cellular circuits. Publication of a new textbook by WH Freeman and Co. is scheduled for December 2014. Supported in part by EF-0928048 and DMR-0832802.

  16. An Efficient Live TV Scheduling System for 4G LTE Broadcast

    KAUST Repository

    Lau, Chun Pong

    2016-01-01

    Traditional live television (TV) broadcasting systems are proven to be spectrum inefficient. Therefore, researchers propose to provide TV services on fourth-generation (4G) long-term evolution (LTE) networks. However, static broadcast, a typical broadcasting method over cellular network, is inefficient in terms of radio resource usage. To solve this problem, the audience-driven live TV scheduling (ADTVS) framework is proposed, to maximize radio resource usage when providing TV broadcasting services over LTE networks. ADTVS, a system-level scheduling framework, considers both available radio resources and audience preferences, in order to dynamically schedule TV channels for broadcasting at various time and locations. By conducting a simulation using real-life data and scenarios, it is shown that ADTVS significantly outperforms the static broadcast method. Numerical results indicate that, on average, ADTVS enables substantial improvement to broadcast efficiency and conserves considerable amount of radio resources, while forgoing less than 5% of user services compared to the benchmark system.

  17. The Systemic Theory of Living Systems and Relevance to CAM: the Theory (Part III

    Directory of Open Access Journals (Sweden)

    José A. Olalde Rangel

    2005-01-01

    Full Text Available Western medical science lacks a solid philosophical and theoretical approach to disease cognition and therapeutics. My first two articles provided a framework for a humane medicine based on Modern Biophysics. Its precepts encompass modern therapeutics and CAM. Modern Biophysics and its concepts are presently missing in medicine, whether orthodox or CAM, albeit they probably provide the long sought explanation that bridges the abyss between East and West. Key points that differentiate Systemic from other systems' approaches are ‘Intelligence’, ‘Energy’ and the objective ‘to survive’. The General System Theory (GST took a forward step by proposing a departure from the mechanistic biological concept—of analyzing parts and processes in isolation—and brought us towards an organismic model. GST examines the system's components and results of their interaction. However, GST still does not go far enough. GST assumes ‘Self-Organization’ as a spontaneous phenomenon, ignoring a causative entity or central controller to all systems: Intelligence. It also neglects ‘Survive’ as the directional motivation common to any living system, and scarcely assigns ‘Energy’ its true inherent value. These three parameters, Intelligence, Energy and Survive, are vital variables to be considered, in our human quest, if we are to achieve a unified theory of life.

  18. Fully synthetic phage-like system for screening mixtures of small molecules in live cells.

    Science.gov (United States)

    Byk, Gerardo; Partouche, Shirly; Weiss, Aryeh; Margel, Shlomo; Khandadash, Raz

    2010-05-10

    A synthetic "phage-like" system was designed for screening mixtures of small molecules in live cells. The core of the system consists of 2 mum diameter cross-linked monodispersed microspheres bearing a panel of fluorescent tags and peptides or small molecules either directly synthesized or covalently conjugated to the microspheres. The microsphere mixtures were screened for affinity to cell line PC-3 (prostate cancer model) by incubation with live cells, and as was with phage-display peptide methods, unbound microspheres were removed by repeated washings followed by total lysis of cells and analysis of the bound microspheres by flow-cytometry. Similar to phage-display peptide screening, this method can be applied even in the absence of prior information about the cellular targets of the candidate ligands, which makes the system especially interesting for selection of molecules with high affinity for desired cells, tissues, or tumors. The advantage of the proposed system is the possibility of screening synthetic non-natural peptides or small molecules that cannot be expressed and screened using phage display libraries. A library composed of small molecules synthesized by the Ugi reaction was screened, and a small molecule, Rak-2, which strongly binds to PC-3 cells was found. Rak-2 was then individually synthesized and validated in a complementary whole cell-based binding assay, as well as by live cell microscopy. This new system demonstrates that a mixture of molecules bound to subcellular sized microspheres can be screened on plated cells. Together with other methods using subcellular sized particles for cellular multiplexing, this method represents an important milestone toward high throughput screening of mixtures of small molecules in live cells and in vivo with potential applications in the fields of drug delivery and diagnostic imaging.

  19. Live from the Arctic

    Science.gov (United States)

    Warnick, W. K.; Haines-Stiles, G.; Warburton, J.; Sunwood, K.

    2003-12-01

    For reasons of geography and geophysics, the poles of our planet, the Arctic and Antarctica, are places where climate change appears first: they are global canaries in the mine shaft. But while Antarctica (its penguins and ozone hole, for example) has been relatively well-documented in recent books, TV programs and journalism, the far North has received somewhat less attention. This project builds on and advances what has been done to date to share the people, places, and stories of the North with all Americans through multiple media, over several years. In a collaborative project between the Arctic Research Consortium of the United States (ARCUS) and PASSPORT TO KNOWLEDGE, Live from the Arctic will bring the Arctic environment to the public through a series of primetime broadcasts, live and taped programming, interactive virtual field trips, and webcasts. The five-year project will culminate during the 2007-2008 International Polar Year (IPY). Live from the Arctic will: A. Promote global understanding about the value and world -wide significance of the Arctic, B. Bring cutting-edge research to both non-formal and formal education communities, C. Provide opportunities for collaboration between arctic scientists, arctic communities, and the general public. Content will focus on the following four themes. 1. Pan-Arctic Changes and Impacts on Land (i.e. snow cover; permafrost; glaciers; hydrology; species composition, distribution, and abundance; subsistence harvesting) 2. Pan-Arctic Changes and Impacts in the Sea (i.e. salinity, temperature, currents, nutrients, sea ice, marine ecosystems (including people, marine mammals and fisheries) 3. Pan-Arctic Changes and Impacts in the Atmosphere (i.e. precipitation and evaporation; effects on humans and their communities) 4. Global Perspectives (i.e. effects on humans and communities, impacts to rest of the world) In The Earth is Faster Now, a recent collection of comments by members of indigenous arctic peoples, arctic

  20. Keeping Up the Live: Recorded Television as Live Experience

    NARCIS (Netherlands)

    van Es, Karin; Keilbach, Judith

    2018-01-01

    textabstractIncreasingly new media platforms are making claims to liveness. Looking back in television history we also find programmes that were recorded, but kept up the claims of being live. This raises the question as to what accounts for the attraction of the live? Focusing on Ein Platz für

  1. Ultra Low-Power Acoustic Detector Applicable in Ambient Assistance Living Systems

    Directory of Open Access Journals (Sweden)

    Iliev I.

    2009-12-01

    Full Text Available Ambient Assisted Living (AAL includes methods, concepts, systems, devices as well as services, which provide unobtrusive support for daily life based on the context and situation of the assisted person. The technologies applied for AAL are user-centric, i.e. oriented towards the needs and capabilities of the particular user. They are also integrated into the immediate personal environment of the user. As a consequence, the technology is adapting to the user rather than the other way around. The in-house monitoring of elderly or disabled people (hard of hearing, deaf, with limited movement ability, using intelligent sensors is a very desirable service that may potentially increase the user's autonomy and independence while minimizing the risks of living alone. The described ultra low-power acoustic detector allows upgrade of the presented warning systems. It features long-term autonomy and possibility to use it as an element of the wireless personal area network (WPAN.

  2. Healthy living after Chernobyl?

    International Nuclear Information System (INIS)

    Schwartau, S.; Rosenkranz, B.

    1987-01-01

    Our food today is endangered not only through environmental poisons and the machinations of profit-hungry manufacturers but also, after the reactor disaster of Chernobyl, by radioactive materials. There is great uncertainty amongst consumers: Whan can I still eat? How can I best protect my children from food products contaminated by radioactivity or enriched with pollutants? Does it still make sense to buy organically produced foodstuffs? Which food products are low in pollutants? With this book the authors want to counteract general helplessness and help the reader with comprehensible and sound information as well as practical tips for eating and living healthily after Chernobyl. (orig.) [de

  3. On The Living Room

    Directory of Open Access Journals (Sweden)

    Thomas Richards

    2013-03-01

    Full Text Available This text discusses the work The Living Room, directed by the author, and reflects on its meanings and functions. The article confronts problems performance raises in relation to contemporary social life, bringing forward the isolation of life today and the possibilities performance offers to fight it. We problematise the crisis experienced by the author and the consequent creation of the work as a mobile performative device in relation to the staging space. Finally, the work questions the forms of interaction and type of participation possible in performance.

  4. Live and let die

    DEFF Research Database (Denmark)

    Næss, Petter

    2004-01-01

    , increased consumption in wealthy countries will reduce the possibility of meeting the needs of a growing population in developing countries within the limits set by the Earth`s ecological carrying capacity. Today, the willingness among the decision makers in rich countries to pursue a sustainable...... article ?Living on a Lifeboat?. Below, Hardin`s ?Lifeboat ethic? is reviewed and critically discussed, focusing on the hidden premises embedded in Hardin`s position. In the final part of the paper, the environmental consequences of economic growth and increasing consumption levels in wealthy nations...

  5. Microencapsulation Of Living Cells

    Science.gov (United States)

    Chang, Manchium; Kendall, James M.; Wang, Taylor G.

    1989-01-01

    In experimental technique, living cells and other biological materials encapsulated within submillimeter-diameter liquid-filled spheres. Sphere material biocompatible, tough, and compliant. Semipermeable, permitting relatively small molecules to move into and out of sphere core but preventing passage of large molecules. New technique promises to make such spherical capsules at high rates and in uniform, controllable sizes. Capsules injected into patient through ordinary hypodermic needle. Promising application for technique in treatment of diabetes. Also used to encapsulate pituitary cells and thyroid hormone adrenocortical cells for treatment of other hormonal disorders, to encapsulate other secreting cells for transplantation, and to package variety of pharmaceutical products and agricultural chemicals for controlled release.

  6. Long ecological half-lives in seminatural systems. Annual report 1996. Project plan 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The EKO-2 project, `Long ecological half-lives in semi-natural systems`, consists of three subprojects; sheep grazing on uncultivated pasture, mushrooms and freshwater fish. The main aim is to identify the contribution from semi-natural systems, by determining ecological half-lives for specific foodstuffs from these areas, and thus determine dose to man. In the three ongoing projects we have produced or used data for 8-10 years after the Chernobyl accident. The time series have been very necessary for predicting ecological half-lives for radiocesium and radiostrontium. Unfortunately, the data for radiostrontium have been very scarce. The recovery of Nordic ecosystems from contamination by {sup 137}Cs originating from the Chernobyl accidents is gradually slowing down, at the same time as areas vary widely in susceptibility and recovery rates. The projects have given us useful understanding of the mechanisms governing the transfer of radionuclides, and more knowledge about typical Nordic ecosystems. The soil - vegetation - sheep - system is being studied in five countries; Iceland, the Faeroe Islands, Denmark, Sweden and Norway. Co-ordinated collection of soil, vegetation and meet samples have been performed every year since 1990. After a slow start in 1994, many results from the project `Transfer of radiocesium via mushrooms to roe deer and man (the forest project)` have been published during 1996. Questionnaires have been implemented in Sweden, Denmark and Finland, in Sweden and Denmark with focus on mushrooms, and a more thorough investigation in Finland on natural products for consumption. The main aim in the project `Ecological half-lives in limnic ecosystems` has been to investigate the processes and mechanisms leading to radiocesium being easily available for uptake in e.g. fish. Systematic collection of data has enabled the construction of a GIS system to show fallout levels of {sup 137}Cs, influence from catchment areas, and prediction of {sup 137}Cs in fish

  7. LAIX-score : a design framework for live audience interaction management systems

    OpenAIRE

    Kuikkaniemi, Kai

    2017-01-01

    This study focuses on computer-supported live audience interaction. In conventional lectures audience interacts explicitly with the performer for example by waving hand and asking question directly or clapping hands. For decades, non digital audience response systems have enabled simple multiple option audience interaction patterns. Modern mobile personal computing devices, digital projectors, wireless networks and real time software platforms enable creation of new kinds of interaction patte...

  8. Flora robotica -- An Architectural System Combining Living Natural Plants and Distributed Robots

    DEFF Research Database (Denmark)

    Hamann, Heiko; Divband Soorati, Mohammad; Heinrich, Mary Katherine

    2017-01-01

    Key to our project flora robotica is the idea of creating a bio-hybrid system of tightly coupled natural plants and distributed robots to grow architectural artifacts and spaces. Our motivation with this ground research project is to lay a principled foundation towards the design and implementation...... of flora robotica, such as the continuous growth process of architectural artifacts and self-repair of living architecture....

  9. Long ecological half-lives in seminatural systems. Annual report 1996. Project plan 1997

    International Nuclear Information System (INIS)

    1997-01-01

    The EKO-2 project, 'Long ecological half-lives in semi-natural systems', consists of three subprojects; sheep grazing on uncultivated pasture, mushrooms and freshwater fish. The main aim is to identify the contribution from semi-natural systems, by determining ecological half-lives for specific foodstuffs from these areas, and thus determine dose to man. In the three ongoing projects we have produced or used data for 8-10 years after the Chernobyl accident. The time series have been very necessary for predicting ecological half-lives for radiocesium and radiostrontium. Unfortunately, the data for radiostrontium have been very scarce. The recovery of Nordic ecosystems from contamination by 137 Cs originating from the Chernobyl accidents is gradually slowing down, at the same time as areas vary widely in susceptibility and recovery rates. The projects have given us useful understanding of the mechanisms governing the transfer of radionuclides, and more knowledge about typical Nordic ecosystems. The soil - vegetation - sheep - system is being studied in five countries; Iceland, the Faeroe Islands, Denmark, Sweden and Norway. Co-ordinated collection of soil, vegetation and meet samples have been performed every year since 1990. After a slow start in 1994, many results from the project 'Transfer of radiocesium via mushrooms to roe deer and man (the forest project)' have been published during 1996. Questionnaires have been implemented in Sweden, Denmark and Finland, in Sweden and Denmark with focus on mushrooms, and a more thorough investigation in Finland on natural products for consumption. The main aim in the project 'Ecological half-lives in limnic ecosystems' has been to investigate the processes and mechanisms leading to radiocesium being easily available for uptake in e.g. fish. Systematic collection of data has enabled the construction of a GIS system to show fallout levels of 137 Cs, influence from catchment areas, and prediction of 137 Cs in fish. (EG)

  10. Attitude toward living kidney donation

    NARCIS (Netherlands)

    Martínez-Alarcón, L.; Ramis, G.; Gómez-Laguna, J.; Quereda, J.J.; Herrero-Medrano, J.M.; Mrowiec, A.; Mendonça, L.; López-Navas, A.; Ríos, A.

    2015-01-01

    Introduction Due to the current deficit of organs for transplantation, living kidney related donations (LKRD) should be promoted. Veterinarians often hold decision-making positions in the public health care system, and therefore can influence public opinion about organ donation. The objective was

  11. Efficient User Authentication and Key Management for Peer-to-Peer Live Streaming Systems

    Institute of Scientific and Technical Information of China (English)

    LIU Xuening; YIN Hao; LIN Chuang; DU Changlai

    2009-01-01

    Recent development of the peer-to-peer (P2P) live streaming technique has brought unprece-dented new momentum to the Internet with the characters of effective, scalable, and low cost. However, be-fore these applications can be successfully deployed as commercial applications, efficient access control mechanisms are needed. This work based on earlier research of the secure streaming architecture in Trust-Stream, analyzes how to ensure that only authorized users can access the original media in the P2P live streaming system by adopting a user authentication and key management scheme. The major features of this system include (1) the management server issues each authorized user a unique public key certificate,(2) the one-way hash chain extends the certificate's lifetime, (3) the original media is encrypted by the ses-sion key and delivered to the communication group, and (4) the session key is periodically updated and dis-tributed with the media. Finally, analyses and test results show that scheme provides a secure, scalable, re-liable, and efficient access control solution for P2P live streaming systems.

  12. An Indoor Positioning System Based on Wearables for Ambient-Assisted Living.

    Science.gov (United States)

    Belmonte-Fernández, Óscar; Puertas-Cabedo, Adrian; Torres-Sospedra, Joaquín; Montoliu-Colás, Raúl; Trilles-Oliver, Sergi

    2016-12-25

    The urban population is growing at such a rate that by 2050 it is estimated that 84% of the world's population will live in cities, with flats being the most common living place. Moreover, WiFi technology is present in most developed country urban areas, with a quick growth in developing countries. New Ambient-Assisted Living applications will be developed in the near future having user positioning as ground technology: elderly tele-care, energy consumption, security and the like are strongly based on indoor positioning information. We present an Indoor Positioning System for wearable devices based on WiFi fingerprinting. Smart-watch wearable devices are used to acquire the WiFi strength signals of the surrounding Wireless Access Points used to build an ensemble of Machine Learning classification algorithms. Once built, the ensemble algorithm is used to locate a user based on the WiFi strength signals provided by the wearable device. Experimental results for five different urban flats are reported, showing that the system is robust and reliable enough for locating a user at room level into his/her home. Another interesting characteristic of the presented system is that it does not require deployment of any infrastructure, and it is unobtrusive, the only device required for it to work is a smart-watch.

  13. An Indoor Positioning System Based on Wearables for Ambient-Assisted Living

    Directory of Open Access Journals (Sweden)

    Óscar Belmonte-Fernández

    2016-12-01

    Full Text Available The urban population is growing at such a rate that by 2050 it is estimated that 84% of the world’s population will live in cities, with flats being the most common living place. Moreover, WiFi technology is present in most developed country urban areas, with a quick growth in developing countries. New Ambient-Assisted Living applications will be developed in the near future having user positioning as ground technology: elderly tele-care, energy consumption, security and the like are strongly based on indoor positioning information. We present an Indoor Positioning System for wearable devices based on WiFi fingerprinting. Smart-watch wearable devices are used to acquire the WiFi strength signals of the surrounding Wireless Access Points used to build an ensemble of Machine Learning classification algorithms. Once built, the ensemble algorithm is used to locate a user based on the WiFi strength signals provided by the wearable device. Experimental results for five different urban flats are reported, showing that the system is robust and reliable enough for locating a user at room level into his/her home. Another interesting characteristic of the presented system is that it does not require deployment of any infrastructure, and it is unobtrusive, the only device required for it to work is a smart-watch.

  14. Temperature - Live Hauling of Fish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In certain markets, live fish can be sold for substantially higher prices than fresh dressed fish. A significant live-haul industry has developed in the U.S. and...

  15. KLA - Live Hauling of Fish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In certain markets, live fish can be sold for substantially higher prices than fresh dressed fish. A significant live-haul industry has developed in the U.S. and...

  16. Tips for Living with Scleroderma

    Science.gov (United States)

    ... Patients Tips for Living Tips for Living with Scleroderma Ways to help manage your symptoms The Scleroderma ... help find improved therapies and a cure for scleroderma! Your gift today will be matched to have ...

  17. CERN's live webcasts

    CERN Multimedia

    IT Department

    2012-01-01

    You may well have noticed when watching the seminar on 4 July that the CERN webcast site has had a makeover.   The new-look site went live on 26 June and provides a detailed schedule of upcoming webcasts as well as easy access to those of recent events.  It is fully compatible with Smartphones and tablets - which wasn't the case until now – and enables viewers to see both the speaker and the presentation, thanks to two separate video recordings. Another innovation: permanent webcasts. In a single click, you can access and view all the channels run by the ATLAS collaboration, including Public Outreach channel, Technical channel and Public Development channel.   And if you want to add your own event to the schedule and broadcast it live via the web,  just go to this address. You can also restrict access to your webcasts to a pre-defined audience. Behind the scenes, the webcast service has also been busy modernising its infrastructure:...

  18. Exotic Long - Lived Particles

    CERN Document Server

    Jørgensen, Morten Dam

    A search for hadronising long-lived massive particles at the Large Hadron Collider is conducted with the ATLAS detector. No excess events are found. Based on statistical analysis, upper limits on the production cross section are observed to be between $0.01$ pb and $0.006$ pb for colour octet particles (gluinos) with masses ranging from $300 \\ \\mathrm{GeV/c}^2$ to $1400 \\ \\mathrm{GeV/c}^2$, and $0.01$ pb to $0.004$ pb for colour triplet particles (stops and sbottoms) with masses ranging from $200 \\ \\mathrm{GeV/c}^2$ to $900 \\ \\mathrm{GeV/c}^2$. In the context of Supersymmetry with decoupled sfermion and sboson sectors (Split-SUSY), this gives a lower limit on the gluino mass of $989 \\ \\mathrm{GeV/c}^2$, and $683 \\ \\mathrm{GeV/c}^2$ for the stop mass and $618 \\ \\mathrm{GeV/c}^2$ for the sbottom mass. In addition, a new method is presented that improves the speed ($\\beta$) estimation for long-lived particles in the ATLAS tile calorimeter with a factor of $7$ improvement in resolution at low-$\\beta$ and ...

  19. Study of genetic markers of CODIS and ESS systems in a population of individuals from Cabo Verde living in Lisboa.

    Science.gov (United States)

    Resende, Ana; Amorim, António; da Silva, Cláudia Vieira; Ribeiro, Teresa; Porto, Maria João; Costa Santos, Jorge; Afonso Costa, Heloísa

    2017-01-01

    Twenty-two autosomal short tandem repeats included in the PowerPlex® Fusion System Amplification kit (Promega Corporation) were genotyped in a population sample of 500 unrelated individuals from Cabo Verde living in Lisboa. Allelic frequency data and forensic and statistical parameters were calculated and evaluated in this work. The genetic relationship among immigrant population from Cabo Verde living in Lisboa and other populations, such as Brazilian and Angola immigrants living in Lisboa; Afro-Americans, Caucasians, Hispanics and Asians living in the USA and the population from Lisboa was assessed, and a multidimensional scaling plot was drown to show these results.

  20. A transportable magnetic resonance imaging system for in situ measurements of living trees: the Tree Hugger.

    Science.gov (United States)

    Jones, M; Aptaker, P S; Cox, J; Gardiner, B A; McDonald, P J

    2012-05-01

    This paper presents the design of the 'Tree Hugger', an open access, transportable, 1.1 MHz (1)H nuclear magnetic resonance imaging system for the in situ analysis of living trees in the forest. A unique construction employing NdFeB blocks embedded in a reinforced carbon fibre frame is used to achieve access up to 210 mm and to allow the magnet to be transported. The magnet weighs 55 kg. The feasibility of imaging living trees in situ using the 'Tree Hugger' is demonstrated. Correlations are drawn between NMR/MRI measurements and other indicators such as relative humidity, soil moisture and net solar radiation. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. Enhanced reality live role playing

    OpenAIRE

    Söderberg, Jonas; Waern, Annika; Åkesson, Karl-Petter; Björk, Staffan; Falk, Jennica

    2004-01-01

    Live role-playing is a form of improvisational theatre played for the experience of the performers and without an audience. These games form a challenging application domain for ubiquitous technology. We discuss the design options for enhanced reality live role-playing and the role of technology in live role-playing games.

  2. Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries

    Science.gov (United States)

    McArdle, Sara; Chodaczek, Grzegorz; Ray, Nilanjan; Ley, Klaus

    2015-02-01

    Intravital multiphoton imaging of arteries is technically challenging because the artery expands with every heartbeat, causing severe motion artifacts. To study leukocyte activity in atherosclerosis, we developed the intravital live cell triggered imaging system (ILTIS). This system implements cardiac triggered acquisition as well as frame selection and image registration algorithms to produce stable movies of myeloid cell movement in atherosclerotic arteries in live mice. To minimize tissue damage, no mechanical stabilization is used and the artery is allowed to expand freely. ILTIS performs multicolor high frame-rate two-dimensional imaging and full-thickness three-dimensional imaging of beating arteries in live mice. The external carotid artery and its branches (superior thyroid and ascending pharyngeal arteries) were developed as a surgically accessible and reliable model of atherosclerosis. We use ILTIS to demonstrate Cx3cr1GFP monocytes patrolling the lumen of atherosclerotic arteries. Additionally, we developed a new reporter mouse (Apoe-/-Cx3cr1GFP/+Cd11cYFP) to image GFP+ and GFP+YFP+ macrophages "dancing on the spot" and YFP+ macrophages migrating within intimal plaque. ILTIS will be helpful to answer pertinent open questions in the field, including monocyte recruitment and transmigration, macrophage and dendritic cell activity, and motion of other immune cells.

  3. A new microcomputer-based safety and life support system for solitary-living elderly people.

    Science.gov (United States)

    Miyauchi, Kosuke; Yonezawa, Yoshiharu; Maki, Hiromichi; Ogawa, Hidekuni; Hahn, Allen W; Caldwell, W Morton

    2003-01-01

    A new safety and life support system has been developed to detect emergency situations of solitary-living elderly persons. The system employs a dual axis accelerometer, two low-power active filters, a low-power 8-bit single chip microcomputer and a personal handy phone. Body movements due to walking, running and posture changes are detected by the dual axis accelerometer and sent to the microcomputer. If the patient is in an inactive state for 5 minutes after falling, or for 64 minutes without previously falling, then the system automatically alarms the emergency situation, via the personal handy phone, to the patient's family, the fire station or the hospital.

  4. Rapid transfer of short-lived radioisotopes via a 2. 4 km rabbit system

    Energy Technology Data Exchange (ETDEWEB)

    Burgerjon, J J; Gelbart, Z; Lau, V; Lehnart, D; Lenz, J; Pate, B D; Ruth, T J; Sprenger, H P; van Oers, N S.C.

    1984-09-01

    A 2.4 km long pipeline between a cyclotron and a hospital is used for the rapid transfer of short-lived radiopharmaceuticals. The vials containing the pharmaceuticals are placed inside capsules (rabbits) that are blown through a tube by means of compressed air. Travel times as short as 2 min are achieved, which makes the system suitable for the transfer of /sup 15/O, which has a 2 min half-life. The construction and test results of the system are described along with a computer model, developed to explain some properties of the system. 7 references, 15 figures, 2 tables.

  5. Multimodal and ubiquitous computing systems: supporting independent-living older users.

    Science.gov (United States)

    Perry, Mark; Dowdall, Alan; Lines, Lorna; Hone, Kate

    2004-09-01

    We document the rationale and design of a multimodal interface to a pervasive/ubiquitous computing system that supports independent living by older people in their own homes. The Millennium Home system involves fitting a resident's home with sensors--these sensors can be used to trigger sequences of interaction with the resident to warn them about dangerous events, or to check if they need external help. We draw lessons from the design process and conclude the paper with implications for the design of multimodal interfaces to ubiquitous systems developed for the elderly and in healthcare, as well as for more general ubiquitous computing applications.

  6. Living with hypertrophic cardiomyopathy.

    Science.gov (United States)

    Subasic, Kim

    2013-12-01

    The purpose of this study is to provide an insider's account of what it is like to live with hypertrophic cardiomyopathy (HCM), a genetic cardiovascular illness that carries the risk for sudden cardiac death. This study aims to reveal how HCM impacts the family and guides the decision whether or not to pursue genetic testing, how the physical limitations associated with HCM alter being-in-the-world, and how HCM alters social relationships. Fifteen adults with HCM were recruited for a longitudinal, phenomenological, qualitative study through purposive sampling and word of mouth. A total of 45 interviews were conducted by the researcher at a time and place designated by the participant between August 2011 and January 2012. The first interview with each participant was conducted in person. While efforts were made to conduct all interviews in person, a total of three interviews were conducted by telephone as requested by three participants due to scheduling conflicts. Through methods of interpretive phenomenology, three audio-recorded, semistructured interviews occurred over the course of 3 months. Detailed narratives were solicited and transcribed verbatim. Methodological and analytical documentation was supported with the identification of key phrases, similar experiences, themes, and documentation of the rationale for decisions throughout the research process. Participation in genetic testing carries a multitude of personal, familial, financial, and emotional implications. The results of a genetic test elicited an emotional response regardless of whether the results were negative, positive, or inconclusive. Living with a potentially life-threatening illness altered identity, disrupted social relationships, and generated chronic fear and uncertainty. A new normal was re-ordered or transformed by the demands and limitations posed by HCM, and by the person's concerns, priorities, and the meaning of the illness. Results from this study underscore the need for healthcare

  7. Broken detailed balance and non-equilibrium dynamics in living systems: a review

    Science.gov (United States)

    Gnesotto, F. S.; Mura, F.; Gladrow, J.; Broedersz, C. P.

    2018-06-01

    Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as high-fidelity transcription and translation, sensing, adaptation, biochemical patterning, and force generation. While biological systems such as motor enzymes violate detailed balance at the molecular scale, it remains unclear how non-equilibrium dynamics manifests at the mesoscale in systems that are driven through the collective activity of many motors. Indeed, in several cellular systems the presence of non-equilibrium dynamics is not always evident at large scales. For example, in the cytoskeleton or in chromosomes one can observe stationary stochastic processes that appear at first glance thermally driven. This raises the question how non-equilibrium fluctuations can be discerned from thermal noise. We discuss approaches that have recently been developed to address this question, including methods based on measuring the extent to which the system violates the fluctuation-dissipation theorem. We also review applications of this approach to reconstituted cytoskeletal networks, the cytoplasm of living cells, and cell membranes. Furthermore, we discuss a more recent approach to detect actively driven dynamics, which is based on inferring broken detailed balance. This constitutes a non-invasive method that uses time-lapse microscopy data, and can be applied to a broad range of systems in cells and tissue. We discuss the ideas underlying this method and its application to several examples including flagella, primary cilia, and cytoskeletal networks. Finally, we briefly discuss recent developments in stochastic thermodynamics and non-equilibrium statistical mechanics, which offer new perspectives to understand the physics of living systems.

  8. Broken detailed balance and non-equilibrium dynamics in living systems: a review.

    Science.gov (United States)

    Gnesotto, F S; Mura, F; Gladrow, J; Broedersz, C P

    2018-03-05

    Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as high-fidelity transcription and translation, sensing, adaptation, biochemical patterning, and force generation. While biological systems such as motor enzymes violate detailed balance at the molecular scale, it remains unclear how non-equilibrium dynamics manifests at the mesoscale in systems that are driven through the collective activity of many motors. Indeed, in several cellular systems the presence of non-equilibrium dynamics is not always evident at large scales. For example, in the cytoskeleton or in chromosomes one can observe stationary stochastic processes that appear at first glance thermally driven. This raises the question how non-equilibrium fluctuations can be discerned from thermal noise. We discuss approaches that have recently been developed to address this question, including methods based on measuring the extent to which the system violates the fluctuation-dissipation theorem. We also review applications of this approach to reconstituted cytoskeletal networks, the cytoplasm of living cells, and cell membranes. Furthermore, we discuss a more recent approach to detect actively driven dynamics, which is based on inferring broken detailed balance. This constitutes a non-invasive method that uses time-lapse microscopy data, and can be applied to a broad range of systems in cells and tissue. We discuss the ideas underlying this method and its application to several examples including flagella, primary cilia, and cytoskeletal networks. Finally, we briefly discuss recent developments in stochastic thermodynamics and non-equilibrium statistical mechanics, which offer new perspectives to understand the physics of living systems.

  9. Neutron scattering to study membrane systems: from lipid vesicles to living cells.

    Energy Technology Data Exchange (ETDEWEB)

    Nickels, Jonathan D. [ORNL; Chatterjee, Sneha [ORNL; Stanley, Christopher B. [ORNL; Qian, Shuo [ORNL; Cheng, Xiaolin [ORNL; Myles, Dean A A [ORNL; Standaert, Robert F. [ORNL; Elkins, James G. [ORNL; Katsaras, John [ORNL

    2017-03-01

    The existence and role of lateral lipid organization in biological membranes has been studied and contested for more than 30 years. Lipid domains, or rafts, are hypothesized as scalable compartments in biological membranes, providing appropriate physical environments to their resident membrane proteins. This implies that lateral lipid organization is associated with a range of biological functions, such as protein co-localization, membrane trafficking, and cell signaling, to name just a few. Neutron scattering techniques have proven to be an excellent tool to investigate these structural features in model lipids, and more recently, in living cells. I will discuss our recent work using neutrons to probe the structure and mechanical properties in model lipid systems and our current efforts in using neutrons to probe the structure and organization of the bilayer in a living cell. These efforts in living cells have used genetic and biochemical strategies to generate a large neutron scattering contrast, making the membrane visible. I will present our results showing in vivo bilayer structure and discuss the outlook for this approach.

  10. New Homes, New Lives?

    DEFF Research Database (Denmark)

    Kolling, Marie

    2016-01-01

    This PhD thesis by Marie Kolling is an ethnography of forced resettlement in the urban periphery of Salvador, Northeast Brazil, and the new lives the families tried to make for themselves in its aftermath in new state-built social housing. The resettlement was part of state-led slum upgrading...... interventions under the urban development project Better Days (Dias Melhores), a name that alludes to the optimism it evoked. As a woman expressed before she was resettled: “a new house, a new life”. The thesis portrays contemporary Brazil and its massive transformations since the beginning of the new...... an analytical framework of four modes of doing housing. It is argued that for the former slum dwellers, doing housing was about doing away with the life in the slum and the stigma pertaining to being a slum dweller. This stigma persisted in the new neighbourhood even though they had moved away from the slum...

  11. Living hours under pressure

    DEFF Research Database (Denmark)

    Ilsøe, Anna; Larsen, Trine Pernille; Felbo-Kolding, Jonas

    2017-01-01

    Purpose The purpose of this paper is to investigate the effect of part-time work on absolute wages. The empirical focus is wages and working hours in three selected sectors within private services in the Danish labour market – industrial cleaning, retail, hotels and restaurants – and their agreem......Purpose The purpose of this paper is to investigate the effect of part-time work on absolute wages. The empirical focus is wages and working hours in three selected sectors within private services in the Danish labour market – industrial cleaning, retail, hotels and restaurants...... in industrial cleaning includes a minimum floor of 15 weekly working hours – this is not the case in retail, hotels and restaurants. This creates a loophole in the latter two sectors that can be exploited by employers to gain wage flexibility through part-time work. Originality/value The living wage literature...

  12. Chernobyl's living legacy

    International Nuclear Information System (INIS)

    Mettler, F.

    2006-01-01

    Twenty years later, the April 1986 Chernobyl accident lives on in different ways: in fact and fiction. Today, national and international experts from eight United Nations agencies including the IAEA are working to sift fact from fiction. They are teamed with Belarus, Russia, and Ukraine to evaluate, document and report the accident's true scale. Known as the Chernobyl Forum, the group issued its comprehensive report in September 2005. It covers health and environmental consequences, and includes recommendations to channel assistance to where it is most needed. Dr. Fred Mettler is a member of the Forum, and a Chernobyl veteran researcher who served as the health team leader in an IAEA-led international project that first presented on-site assessments of Chernobyl's effects in the early 1990s, and participated in the International Chernobyl Conference in 1996 that summed up what was scientifically known then. In this essay, he revisits Chernobyl's health picture from personal and professional perspectives

  13. Living on the edge.

    Science.gov (United States)

    Hinrichsen, D

    1989-01-01

    A brief update on the destruction of the environment is given. The concern is for the coastal waters and rivers which are polluted daily by raw sewage, industrial waste, and sedimentation, e.g., the Juru in Malaysia, the Pasig in the Philippines, and the Chao Phraya in Thailand are open sewers by the time the rivers reach the sea or bay. Metropolitan Manila's river is said to be biologically dead from pollution, and the bays of Manila and Jakarta suffer from oxygen depletion. Unfortunately, the coastal area maintains population as well as the wealth of marine life. In the US in 1990, 75% of the population will live within 50 miles of a shore including the Great Lakes. 30 southeast Asia's 50 largest cities are located on or near a coast. Over fishing, over population, over developing, and over exploitation are unacceptable; the alternative is for man to correct his mistakes.

  14. He Lived among us

    Science.gov (United States)

    Pokrovsky, V. L.

    2013-06-01

    I initially got acquainted with Anatoly Larkin at the first Odessa theoretical school, probably in 1959. Amid the brilliant company gathered in Odessa (Abrikosov, Khalatnikov, Gorkov, Keldysh, Perel, Pitaevsky), he astonished me at the time with his fundamentality, the soundness of his judgment and the ease of his receptiveness to new ideas. Later in Novosibirsk, where I lived then, Roald Sagdeev told me A. B. Migdal, Tolya's research supervisor for graduate work, had invited Tolya to move with him to Novosibirsk, to the Budker Institute of Nuclear Physics, with the promise of a fast-track academic career. Tolya refused, and then A.B., who held Tolya's opinion and collaboration in high regard, also decided to stay in Moscow...

  15. Living with psoriasis

    DEFF Research Database (Denmark)

    Bak, Kirsten Tarri

    2004-01-01

    Living with psoriasis is a considerable burden and quality of life in patients is deeply affected, yet compliance with therapy is a major problem. The literature is abundant in quantitative studies stating the incidence of decrease in quality of life and related, measurable terms, and in efforts...... directed at the improvement of therapies. However, it is sparse concerning the experiences of patients. This study aims to promote an understanding of the daily life of patients with psoriasis with particular regard to how they manage the disease, ultimately to improve nursing care to these patients....... A qualitative, collective case study design was applied. The participants were 4 adult patients with a long and complicated psoriasis history. They were interviewed in depth focusing on their experiences related to psoriasis and its treatment. The patients suffered physically from itch and pain. However...

  16. Living with a disability

    DEFF Research Database (Denmark)

    Jespersen, Louise Norman; Michelsen, Susan Ishøy; Tjørnhøj-thomsen, Tine

    2018-01-01

    highlighted as affecting quality of life. The use of social tactics to avoid confrontation with certain aspects of their disability was common among participants. Conclusions: Across disabilities, caregiving, dependency, understanding and acceptance, and discrimination and prejudice were all important aspects......Purpose: We explored which shared aspects of social relations were considered important to the quality of life of persons between the ages of 10 and 40 years living with a disability. We examined how social relations were experienced as affecting quality of life and social participation. Materials...... and methods: Fifteen focus groups involving 48 persons with disabilities were conducted using photo elicitation, preference ranking and props. Focus group interviews were supplemented with seven individual interviews with individuals unable to participate in focus groups. All focus group interviews...

  17. Health and urban living.

    Science.gov (United States)

    Dye, Christopher

    2008-02-08

    The majority of people now live in urban areas and will do so for the foreseeable future. As a force in the demographic and health transition, urbanization is associated with falling birth and death rates and with the shift in burden of illness from acute childhood infections to chronic, noncommunicable diseases of adults. Urban inhabitants enjoy better health on average than their rural counterparts, but the benefits are usually greater for the rich than for the poor, thus magnifying the differences between them. Subject to better evidence, I suggest that the main obstacles to improving urban health are not technical or even financial, but rather are related to governance and the organization of civil society.

  18. Living with radiation

    International Nuclear Information System (INIS)

    Tymen, G.

    1999-01-01

    This editorial article discusses the various forms of radiation that we live with. In particular, the general public's lack of knowledge on the subject is mentioned and the concentration of the media on radiation accidents and emissions is looked at critically. The various forms of radiation - ionising and non-ionising - are briefly discussed. Natural ionising radiation sources and in particular radon are described and the increasing proportion of doses attributed to cosmic radiation met in high-flying aircraft and radiation doses resulting from medical examination and treatment are discussed. Non-ionising radiation such as electromagnetic fields generated by power lines, mobile telephones and kitchen equipment and their implications on health are also looked at

  19. Long-Range Untethered Real-Time Live Gas Main Robotic Inspection System

    Energy Technology Data Exchange (ETDEWEB)

    Hagen Schempf; Daphne D' Zurko

    2004-10-31

    Under funding from the Department of Energy (DOE) and the Northeast Gas Association (NGA), Carnegie Mellon University (CMU) developed an untethered, wireless remote controlled inspection robot dubbed Explorer. The project entailed the design and prototyping of a wireless self-powered video-inspection robot capable of accessing live 6- and 8-inch diameter cast-iron and steel mains, while traversing turns and Ts and elbows under real-time control with live video feedback to an operator. The design is that of a segmented actively articulated and wheel-leg powered robot design, with fisheye imaging capability and self-powered battery storage and wireless real-time communication link. The prototype was functionally tested in an above ground pipe-network, in order to debug all mechanical, electrical and software subsystems, and develop the necessary deployment and retrieval, as well as obstacle-handling scripts. A pressurized natural gas test-section was used to certify it for operation in natural gas at up to 60 psig. Two subsequent live-main field-trials in both cast-iron and steel pipe, demonstrated its ability to be safely launched, operated and retrieved under real-world conditions. The system's ability to safely and repeatably exidrecover from angled and vertical launchers, traverse multi-thousand foot long pipe-sections, make T and varied-angle elbow-turns while wirelessly sending live video and handling command and control messages, was clearly demonstrated. Video-inspection was clearly shown to be a viable tool to understand the state of this critical buried infrastructure, irrespective of low- (cast-iron) or high-pressure (steel) conditions. This report covers the different aspects of specifications, requirements, design, prototyping, integration and testing and field-trialing of the Explorer platform.

  20. Experiencing Liveness in Contemporary Performance

    DEFF Research Database (Denmark)

    bring qualities of (a)liveness into being through the nature of their attention - and how it becomes materialized in acts of performance, acts of making, acts of archiving, and acts of remembering. Theoretical chapters and practice-based reflections explore liveness, eventness and nowness as key......This volume brings together dynamic perspectives on the concept of liveness in the performing arts, engaging with the live through the particular analytical focus of audiences and experience. The status and significance of the live in performance has become contested: perceived as variously...... of making. Drawing together contributions from theatre, music, dance, and performance art, it takes an interdisciplinary approach in asking not what liveness is, but how it matters and to whom. The book invites readers to consider how liveness is produced through processes of audiencing - as spectators...

  1. An integrated on-line irradiation and in situ live cell imaging system

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Ying; Fu, Qibin; Wang, Weikang; Liu, Yu; Liu, Feng; Yang, Gen, E-mail: gen.yang@pku.edu.cn; Wang, Yugang

    2015-09-01

    Ionizing radiation poses a threat to genome integrity by introducing DNA damages, particularly DNA double-strand breaks (DSB) in cells. Understanding how cells react to DSB and maintain genome integrity is of major importance, since increasing evidences indicate the links of DSB with genome instability and cancer predispositions. However, tracking the dynamics of DNA damages and repair response to ionizing radiation in individual cell is difficult. Here we describe the development of an on-line irradiation and in situ live cell imaging system based on isotopic sources at Institute of Heavy Ion Physics, Peking University. The system was designed to irradiate cells and in situ observe the cellular responses to ionizing radiation in real time. On-line irradiation was achieved by mounting a metal framework that hold an isotopic γ source above the cell culture dish for γ irradiation; or by integrating an isotopic α source to an objective lens under the specialized cell culture dish for α irradiation. Live cell imaging was performed on a confocal microscope with an environmental chamber installed on the microscope stage. Culture conditions in the environment chamber such as CO{sub 2}, O{sub 2} concentration as well as temperature are adjustable, which further extends the capacity of the system and allows more flexible experimental design. We demonstrate the use of this system by tracking the DSB foci formation and disappearance in individual cells after exposure to irradiation. On-line irradiation together with in situ live cell imaging in adjustable culture conditions, the system overall provides a powerful tool for investigation of cellular and subcellular response to ionizing radiation under different physiological conditions such as hyperthermia or hypoxia.

  2. An integrated on-line irradiation and in situ live cell imaging system

    International Nuclear Information System (INIS)

    Liang, Ying; Fu, Qibin; Wang, Weikang; Liu, Yu; Liu, Feng; Yang, Gen; Wang, Yugang

    2015-01-01

    Ionizing radiation poses a threat to genome integrity by introducing DNA damages, particularly DNA double-strand breaks (DSB) in cells. Understanding how cells react to DSB and maintain genome integrity is of major importance, since increasing evidences indicate the links of DSB with genome instability and cancer predispositions. However, tracking the dynamics of DNA damages and repair response to ionizing radiation in individual cell is difficult. Here we describe the development of an on-line irradiation and in situ live cell imaging system based on isotopic sources at Institute of Heavy Ion Physics, Peking University. The system was designed to irradiate cells and in situ observe the cellular responses to ionizing radiation in real time. On-line irradiation was achieved by mounting a metal framework that hold an isotopic γ source above the cell culture dish for γ irradiation; or by integrating an isotopic α source to an objective lens under the specialized cell culture dish for α irradiation. Live cell imaging was performed on a confocal microscope with an environmental chamber installed on the microscope stage. Culture conditions in the environment chamber such as CO 2 , O 2 concentration as well as temperature are adjustable, which further extends the capacity of the system and allows more flexible experimental design. We demonstrate the use of this system by tracking the DSB foci formation and disappearance in individual cells after exposure to irradiation. On-line irradiation together with in situ live cell imaging in adjustable culture conditions, the system overall provides a powerful tool for investigation of cellular and subcellular response to ionizing radiation under different physiological conditions such as hyperthermia or hypoxia

  3. An integrated on-line irradiation and in situ live cell imaging system

    Science.gov (United States)

    Liang, Ying; Fu, Qibin; Wang, Weikang; Liu, Yu; Liu, Feng; Yang, Gen; Wang, Yugang

    2015-09-01

    Ionizing radiation poses a threat to genome integrity by introducing DNA damages, particularly DNA double-strand breaks (DSB) in cells. Understanding how cells react to DSB and maintain genome integrity is of major importance, since increasing evidences indicate the links of DSB with genome instability and cancer predispositions. However, tracking the dynamics of DNA damages and repair response to ionizing radiation in individual cell is difficult. Here we describe the development of an on-line irradiation and in situ live cell imaging system based on isotopic sources at Institute of Heavy Ion Physics, Peking University. The system was designed to irradiate cells and in situ observe the cellular responses to ionizing radiation in real time. On-line irradiation was achieved by mounting a metal framework that hold an isotopic γ source above the cell culture dish for γ irradiation; or by integrating an isotopic α source to an objective lens under the specialized cell culture dish for α irradiation. Live cell imaging was performed on a confocal microscope with an environmental chamber installed on the microscope stage. Culture conditions in the environment chamber such as CO2, O2 concentration as well as temperature are adjustable, which further extends the capacity of the system and allows more flexible experimental design. We demonstrate the use of this system by tracking the DSB foci formation and disappearance in individual cells after exposure to irradiation. On-line irradiation together with in situ live cell imaging in adjustable culture conditions, the system overall provides a powerful tool for investigation of cellular and subcellular response to ionizing radiation under different physiological conditions such as hyperthermia or hypoxia.

  4. Living Mulch Performance in a Tropical Cotton System and Impact on Yield and Weed Control

    Directory of Open Access Journals (Sweden)

    Vinay Bhaskar

    2018-01-01

    Full Text Available Cotton (Gossypium hirsutum L. is a major crop in the Vidarbha region of central India. The vertisol soils on which much of the cotton is grown have been severely degraded by the tropical climate, excessive tillage and depletion of organic matter. Living mulches have the ability to mitigate these problems but they can cause crop losses through direct competition with the cotton crop and unreliable weed control. Field experiments were conducted in 2012 and 2013 at four locations in Vidarbha to study the potential for growing living mulches in mono-cropped cotton. Living mulch species evaluated included gliricidia [Gliricidia sepium (Jacq. Kunth ex Walp.], sesbania [Sesbania sesban (L. Merr.], sorghum sudan grass [Sorghum bicolor (L. Moench × Sorghum bicolor (L. Moench ssp. Drummondii (Nees ex Steud. de Wet & Harlan] and sunnhemp (Crotalaria juncea L.. Living mulch height was controlled through mowing and herbicides were not used. Living mulches generated 1 to 13 tons ha−1 of dry matter across sites and years. Weed cover was negatively correlated with both living mulch biomass and cover. Where living mulches were vigorous and established quickly, weed cover was as low as 7%, without the use of herbicides, or inter-row tillage. In a dry year, living mulch growth had a negative impact on cotton yield; however, in a year when soil moisture was not limiting, there was a positive relationship between cotton yield and living mulch biomass. Use of living mulches in cotton production in the Vidarbha region of India is feasible and can lead to both effective weed suppression and acceptable cotton yields.

  5. Progress in ambient assisted systems for independent living by the elderly.

    Science.gov (United States)

    Al-Shaqi, Riyad; Mourshed, Monjur; Rezgui, Yacine

    2016-01-01

    One of the challenges of the ageing population in many countries is the efficient delivery of health and care services, which is further complicated by the increase in neurological conditions among the elderly due to rising life expectancy. Personal care of the elderly is of concern to their relatives, in case they are alone in their homes and unforeseen circumstances occur, affecting their wellbeing. The alternative; i.e. care in nursing homes or hospitals is costly and increases further if specialized care is mobilized to patients' place of residence. Enabling technologies for independent living by the elderly such as the ambient assisted living systems (AALS) are seen as essential to enhancing care in a cost-effective manner. In light of significant advances in telecommunication, computing and sensor miniaturization, as well as the ubiquity of mobile and connected devices embodying the concept of the Internet of Things (IoT), end-to-end solutions for ambient assisted living have become a reality. The premise of such applications is the continuous and most often real-time monitoring of the environment and occupant behavior using an event-driven intelligent system, thereby providing a facility for monitoring and assessment, and triggering assistance as and when needed. As a growing area of research, it is essential to investigate the approaches for developing AALS in literature to identify current practices and directions for future research. This paper is, therefore, aimed at a comprehensive and critical review of the frameworks and sensor systems used in various ambient assisted living systems, as well as their objectives and relationships with care and clinical systems. Findings from our work suggest that most frameworks focused on activity monitoring for assessing immediate risks, while the opportunities for integrating environmental factors for analytics and decision-making, in particular for the long-term care were often overlooked. The potential for

  6. An Indoor Monitoring System for Ambient Assisted Living Based on Internet of Things Architecture

    Science.gov (United States)

    Marques, Gonçalo; Pitarma, Rui

    2016-01-01

    The study of systems and architectures for ambient assisted living (AAL) is undoubtedly a topic of great relevance given the aging of the world population. The AAL technologies are designed to meet the needs of the aging population in order to maintain their independence as long as possible. As people typically spend more than 90% of their time in indoor environments, indoor air quality (iAQ) is perceived as an imperative variable to be controlled for the inhabitants’ wellbeing and comfort. Advances in networking, sensors, and embedded devices have made it possible to monitor and provide assistance to people in their homes. The continuous technological advancements make it possible to build smart objects with great capabilities for sensing and connecting several possible advancements in ambient assisted living systems architectures. Indoor environments are characterized by several pollutant sources. Most of the monitoring frameworks instantly accessible are exceptionally costly and only permit the gathering of arbitrary examples. iAQ is an indoor air quality system based on an Internet of Things paradigm that incorporates in its construction Arduino, ESP8266, and XBee technologies for processing and data transmission and micro sensors for data acquisition. It also allows access to data collected through web access and through a mobile application in real time, and this data can be accessed by doctors in order to support medical diagnostics. Five smaller scale sensors of natural parameters (air temperature, moistness, carbon monoxide, carbon dioxide, and glow) were utilized. Different sensors can be included to check for particular contamination. The results reveal that the system can give a viable indoor air quality appraisal in order to anticipate technical interventions for improving indoor air quality. Indeed indoor air quality might be distinctively contrasted with what is normal for a quality living environment. PMID:27869682

  7. An Indoor Monitoring System for Ambient Assisted Living Based on Internet of Things Architecture

    Directory of Open Access Journals (Sweden)

    Gonçalo Marques

    2016-11-01

    Full Text Available The study of systems and architectures for ambient assisted living (AAL is undoubtedly a topic of great relevance given the aging of the world population. The AAL technologies are designed to meet the needs of the aging population in order to maintain their independence as long as possible. As people typically spend more than 90% of their time in indoor environments, indoor air quality (iAQ is perceived as an imperative variable to be controlled for the inhabitants’ wellbeing and comfort. Advances in networking, sensors, and embedded devices have made it possible to monitor and provide assistance to people in their homes. The continuous technological advancements make it possible to build smart objects with great capabilities for sensing and connecting several possible advancements in ambient assisted living systems architectures. Indoor environments are characterized by several pollutant sources. Most of the monitoring frameworks instantly accessible are exceptionally costly and only permit the gathering of arbitrary examples. iAQ is an indoor air quality system based on an Internet of Things paradigm that incorporates in its construction Arduino, ESP8266, and XBee technologies for processing and data transmission and micro sensors for data acquisition. It also allows access to data collected through web access and through a mobile application in real time, and this data can be accessed by doctors in order to support medical diagnostics. Five smaller scale sensors of natural parameters (air temperature, moistness, carbon monoxide, carbon dioxide, and glow were utilized. Different sensors can be included to check for particular contamination. The results reveal that the system can give a viable indoor air quality appraisal in order to anticipate technical interventions for improving indoor air quality. Indeed indoor air quality might be distinctively contrasted with what is normal for a quality living environment.

  8. An Indoor Monitoring System for Ambient Assisted Living Based on Internet of Things Architecture.

    Science.gov (United States)

    Marques, Gonçalo; Pitarma, Rui

    2016-11-17

    The study of systems and architectures for ambient assisted living (AAL) is undoubtedly a topic of great relevance given the aging of the world population. The AAL technologies are designed to meet the needs of the aging population in order to maintain their independence as long as possible. As people typically spend more than 90% of their time in indoor environments, indoor air quality (iAQ) is perceived as an imperative variable to be controlled for the inhabitants' wellbeing and comfort. Advances in networking, sensors, and embedded devices have made it possible to monitor and provide assistance to people in their homes. The continuous technological advancements make it possible to build smart objects with great capabilities for sensing and connecting several possible advancements in ambient assisted living systems architectures. Indoor environments are characterized by several pollutant sources. Most of the monitoring frameworks instantly accessible are exceptionally costly and only permit the gathering of arbitrary examples. iAQ is an indoor air quality system based on an Internet of Things paradigm that incorporates in its construction Arduino, ESP8266, and XBee technologies for processing and data transmission and micro sensors for data acquisition. It also allows access to data collected through web access and through a mobile application in real time, and this data can be accessed by doctors in order to support medical diagnostics. Five smaller scale sensors of natural parameters (air temperature, moistness, carbon monoxide, carbon dioxide, and glow) were utilized. Different sensors can be included to check for particular contamination. The results reveal that the system can give a viable indoor air quality appraisal in order to anticipate technical interventions for improving indoor air quality. Indeed indoor air quality might be distinctively contrasted with what is normal for a quality living environment.

  9. [Evaluation of data on live birth certificates from the Information System on Live Births (SINASC) in Campinas, São Paulo, 2009].

    Science.gov (United States)

    Gabriel, Guilherme Paiva; Chiquetto, Letícia; Morcillo, André Moreno; Ferreira, Maria do Carmo; Bazan, Ivan Gilberto M; Daolio, Luísa Dias; Lemos, Jéssica J Rocha; Carniel, Emília de Faria

    2014-09-01

    To assess the completeness and reliability of the Information System on Live Births (Sinasc) data. A cross-sectional analysis of the reliability and completeness of Sinasc's data was performed using a sample of Live Birth Certificate (LBC) from 2009, related to births from Campinas, Southeast Brazil. For data analysis, hospitals were grouped according to category of service (Unified National Health System, private or both), 600 LBCs were randomly selected and the data were collected in LBC-copies through mothers and newborns' hospital records and by telephone interviews. The completeness of LBCs was evaluated, calculating the percentage of blank fields, and the LBCs agreement comparing the originals with the copies was evaluated by Kappa and intraclass correlation coefficients. The percentage of completeness of LBCs ranged from 99.8%-100%. For the most items, the agreement was excellent. However, the agreement was acceptable for marital status, maternal education and newborn infants' race/color, low for prenatal visits and presence of birth defects, and very low for the number of deceased children. The results showed that the municipality Sinasc is reliable for most of the studied variables. Investments in training of the professionals are suggested in an attempt to improve system capacity to support planning and implementation of health activities for the benefit of maternal and child population. Copyright © 2014 Sociedade de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  10. A Web Services based system for the distribution of live information at the FTU fusion experiment

    International Nuclear Information System (INIS)

    Boncagni, L.; Centioli, C.; Lattanzio, L.; Panella, M.; Torelli, C.; Zaccarian, L.

    2009-01-01

    In this paper we describe LiveMonitor, an integrated system realized for the distribution of information in fusion environments. The software tool is based on a client-server approach, where the server side consists of a set of Web Services that collect data from a variety of data sources. LiveMonitor has been successfully used at FTU, replacing and enhancing part of the core of the current message broadcasting system. The tool integrates all the information needed by the control room personnel during the experiments, namely the shot sequence status coming from the FTU Control System, videos of the plasma discharge from the FTU ports cameras, and fresh data from the databases. From the hardware point of view, the new system is made of a Linux node running the Web Services, while clients running on other machines can display information on large (46 '' ) LCD monitors. The tool has been tested during FTU experiments and can be further expanded to match the needs of the control room personnel and experimental physicists.

  11. Complexity for survival of livings

    International Nuclear Information System (INIS)

    Zak, Michail

    2007-01-01

    A connection between survivability of livings and complexity of their behavior is established. New physical paradigms-exchange of information via reflections, and chain of abstractions-explaining and describing progressive evolution of complexity in living (active) systems are introduced. A biological origin of these paradigms is associated with a recently discovered mirror neuron that is able to learn by imitation. As a result, an active element possesses the self-nonself images and interacts with them creating the world of mental dynamics. Three fundamental types of complexity of mental dynamics that contribute to survivability are identified. Mathematical model of the corresponding active systems is described by coupled motor-mental dynamics represented by Langevin and Fokker-Planck equations, respectively, while the progressive evolution of complexity is provided by nonlinear evolution of probability density. Application of the proposed formalism to modeling common-sense-based decision-making process is discussed

  12. Complexity for survival of livings

    Energy Technology Data Exchange (ETDEWEB)

    Zak, Michail [Jet Propulsion Laboratory, California Institute of Technology, Advance Computing Algorithms and IVHM Group, Pasadena, CA 91109 (United States)]. E-mail: Michail.Zak@jpl.nasa.gov

    2007-05-15

    A connection between survivability of livings and complexity of their behavior is established. New physical paradigms-exchange of information via reflections, and chain of abstractions-explaining and describing progressive evolution of complexity in living (active) systems are introduced. A biological origin of these paradigms is associated with a recently discovered mirror neuron that is able to learn by imitation. As a result, an active element possesses the self-nonself images and interacts with them creating the world of mental dynamics. Three fundamental types of complexity of mental dynamics that contribute to survivability are identified. Mathematical model of the corresponding active systems is described by coupled motor-mental dynamics represented by Langevin and Fokker-Planck equations, respectively, while the progressive evolution of complexity is provided by nonlinear evolution of probability density. Application of the proposed formalism to modeling common-sense-based decision-making process is discussed.

  13. Tantalum-178 - a short-lived nuclide for nuclear medicine: development of a potential generator system

    International Nuclear Information System (INIS)

    Neirinckx, R.D.; Jones, A.G.; Davis, M.A.; Harris, G.I.; Holman, B.L.

    1978-01-01

    We describe a chemical separation that may form the basis of a generator system for the short-lived radionuclide Ta-178 (T/sub 1/2/ = 9 min). The parent nuclide W-178 (T/sub 1/2/ = 21.7 days) is loaded on an anion-exchange column and the daughter eluted with a mixture of dilute hydrochloric acid and hydrogen peroxide. The yields of tantalum and the breakthrough of the tungsten parent as a function of the eluting conditions are discussed, and preliminary animal distribution data are presented for various treatments of the eluant solution

  14. Evolution of an Early Illness Warning System to Monitor Frail Elders in Independent Living

    Directory of Open Access Journals (Sweden)

    Gregory L. Alexander

    2011-01-01

    Full Text Available This paper describes the evolution of an early illness warning system used by an interdisciplinary team composed of clinicians and engineers in an independent living facility. The early illness warning system consists of algorithms which analyze resident activity patterns obtained from sensors embedded in residents' apartments. The engineers designed an automated reasoning system to generate clinically relevant alerts which are sent to clinicians when significant changes occur in the sensor data, for example declining activity levels. During January 2010 through July 2010, clinicians and engineers conducted weekly iterative review cycles of the early illness warning system to discuss concerns about the functionality of the warning system, to recommend solutions for the concerns, and to evaluate the implementation of the solutions. A total of 45 concerns were reviewed during this period. Iterative reviews resulted in greater efficiencies and satisfaction for clinician users who were monitoring elder activity patterns.

  15. Development of Automatic Live Linux Rebuilding System with Flexibility in Science and Engineering Education and Applying to Information Processing Education

    Science.gov (United States)

    Sonoda, Jun; Yamaki, Kota

    We develop an automatic Live Linux rebuilding system for science and engineering education, such as information processing education, numerical analysis and so on. Our system is enable to easily and automatically rebuild a customized Live Linux from a ISO image of Ubuntu, which is one of the Linux distribution. Also, it is easily possible to install/uninstall packages and to enable/disable init daemons. When we rebuild a Live Linux CD using our system, we show number of the operations is 8, and the rebuilding time is about 33 minutes on CD version and about 50 minutes on DVD version. Moreover, we have applied the rebuilded Live Linux CD in a class of information processing education in our college. As the results of a questionnaires survey from our 43 students who used the Live Linux CD, we obtain that the our Live Linux is useful for about 80 percents of students. From these results, we conclude that our system is able to easily and automatically rebuild a useful Live Linux in short time.

  16. Energy - quality of living

    International Nuclear Information System (INIS)

    Kutsch, K.

    1981-01-01

    In order to develop the new potentials in life - short working hours, ample leisure time, high quantity of production - logically a tremendous multiplication of labour productivity is necessary. It was the 'industrial revolution' which created our present world by blending the powers of the mind with the powers of nature. Without the current means of energy release our mode of life is unthinkable. The Conservation Commission of the World Energy Conference comes to the conclusion that under the premisses of a doupling of the world population by the year 2020 the demand for primary energy will increase 3.6 fold to 34 billion SKE (units of mineral coal). The outlook on world energy supply shows that even providing for all means of energy saving and application of alternative sources of energy the energy demand can not be satisfied without nuclear power. Without sufficient supply of energy securing a living of a certain quality for the increasing world population is not possible. Every progress, however, has its dangers. There is no technology without risk. (orig.) [de

  17. Raman tweezers in microfluidic systems for analysis and sorting of living cells

    Science.gov (United States)

    Pilát, Zdeněk.; Ježek, Jan; Kaňka, Jan; Zemánek, Pavel

    2014-12-01

    We have devised an analytical and sorting system combining optical trapping with Raman spectroscopy in microfluidic environment, dedicated to identification and sorting of biological objects, such as living cells of various unicellular organisms. Our main goal was to create a robust and universal platform for non-destructive and non-contact sorting of micro-objects based on their Raman spectral properties. This approach allowed us to collect spectra containing information about the chemical composition of the objects, such as the presence and composition of pigments, lipids, proteins, or nucleic acids, avoiding artificial chemical probes such as fluorescent markers. The non-destructive nature of this optical analysis and manipulation allowed us to separate individual living cells of our interest in a sterile environment and provided the possibility to cultivate the selected cells for further experiments. We used a mixture of polystyrene micro-particles and algal cells to test and demonstrate the function of our analytical and sorting system. The devised system could find its use in many medical, biotechnological, and biological applications.

  18. Model System for Live Imaging of Neuronal Responses to Injury and Repair

    Directory of Open Access Journals (Sweden)

    Mathieu Gravel

    2011-11-01

    Full Text Available Although it has been well established that induction of growth-associated protein-43 (GAP-43 during development coincides with axonal outgrowth and early synapse formation, the existence of neuronal plasticity and neurite outgrowth in the adult central nervous system after injuries is more controversial. To visualize the processes of neuronal injury and repair in living animals, we generated reporter mice for bioluminescence and fluorescence imaging bearing the luc (luciferase and gfp (green fluorescent protein reporter genes under the control of the murine GAP-43 promoter. Reporter functionality was first observed during the development of transgenic embryos. Using in vivo bioluminescence and fluorescence imaging, we visualized induction of the GAP-43 signals from live embryos starting at E10.5, as well as neuronal responses to brain and peripheral nerve injuries (the signals peaked at 14 days postinjury. Moreover, three-dimensional analysis of the GAP-43 bioluminescent signal confirmed that it originated from brain structures affected by ischemic injury. The analysis of fluorescence signal at cellular level revealed colocalization between endogenous protein and the GAP-43-driven gfp transgene. Taken together, our results suggest that the GAP-43-luc/gfp reporter mouse represents a valid model system for real-time analysis of neurite outgrowth and the capacity of the adult nervous system to regenerate after injuries.

  19. Active living and biking: tracing the evolution of a biking system in Arlington, Virginia.

    Science.gov (United States)

    Hanson, Royce; Young, Garry

    2008-06-01

    In Arlington, Virginia, a steady evolutionary change in biking policy during the last three decades has yielded some of the nation's best biking assets. It has a comprehensive, well-connected, highly integrated, well-mapped, and well-signed system of shared-use paved trails, bike lanes, bike routes, and other biking assets, such as workplace showers. Understanding the conditions that led to Arlington's current biking system can provide lessons in the strategy and tactics of active-living politics. One potentially effective political strategy that was successful in Arlington is for activists to pressure elected officials to select professional managers who see bike-ways as crucial to the overall transportation system. Then it is important to formalize the government-citizen relationship through an advisory panel. Also, in Arlington, the incremental creation of biking assets helped create demand for more and better facilities. In turn, this created political support for expanding and upgrading. Finally, Arlington used potentially negative circumstances (e.g., the building of highway corridors, the introduction of the Metro) as opportunities to change the built environment in ways that have encouraged more active living.

  20. Environments of Long-Lived Mesoscale Convective Systems Over the Central United States in Convection Permitting Climate Simulations: Long-Lived Mesoscale Convective Systems

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Qing [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Houze, Robert A. [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Department of Atmospheric Sciences, University of Washington, Seattle WA USA; Leung, L. Ruby [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA; Feng, Zhe [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland WA USA

    2017-12-27

    Continental-scale convection-permitting simulations of the warm seasons of 2011 and 2012 reproduce realistic structure and frequency distribution of lifetime and event mean precipitation of mesoscale convective systems (MCSs) over the central United States. Analysis is performed to determine the environmental conditions conducive to generating the longest-lived MCSs and their subsequent interactions. The simulations show that MCSs systematically form over the Great Plains ahead of a trough in the westerlies in combination with an enhanced low-level jet from the Gulf of Mexico. These environmental properties at the time of storm initiation are most prominent for the MCSs that persist for the longest times. Systems reaching 9 h or more in lifetime exhibit feedback to the environment conditions through diabatic heating in the MCS stratiform regions. As a result, the parent synoptic-scale wave is strengthened as a divergent perturbation develops over the MCS at high levels, while a cyclonic circulation perturbation develops in the midlevels of the trough, where the vertical gradient of heating in the MCS region is maximized. The quasi-balanced mesoscale vortex helps to maintain the MCS over a long period of time by feeding dry, cool air into the environment at the rear of the MCS region, so that the MCS can draw in air that increases the evaporative cooling that helps maintain the MCS. At lower levels the south-southeasterly jet of warm moist air from the Gulf is enhanced in the presence of the synoptic-scale wave. That moisture supply is essential to the continued redevelopment of the MCS.

  1. Saving Human Lives: What Complexity Science and Information Systems can Contribute

    Science.gov (United States)

    Helbing, Dirk; Brockmann, Dirk; Chadefaux, Thomas; Donnay, Karsten; Blanke, Ulf; Woolley-Meza, Olivia; Moussaid, Mehdi; Johansson, Anders; Krause, Jens; Schutte, Sebastian; Perc, Matjaž

    2015-02-01

    We discuss models and data of crowd disasters, crime, terrorism, war and disease spreading to show that conventional recipes, such as deterrence strategies, are often not effective and sufficient to contain them. Many common approaches do not provide a good picture of the actual system behavior, because they neglect feedback loops, instabilities and cascade effects. The complex and often counter-intuitive behavior of social systems and their macro-level collective dynamics can be better understood by means of complexity science. We highlight that a suitable system design and management can help to stop undesirable cascade effects and to enable favorable kinds of self-organization in the system. In such a way, complexity science can help to save human lives.

  2. A Checklist for Successful Quantitative Live Cell Imaging in Systems Biology

    Science.gov (United States)

    Sung, Myong-Hee

    2013-01-01

    Mathematical modeling of signaling and gene regulatory networks has provided unique insights about systems behaviors for many cell biological problems of medical importance. Quantitative single cell monitoring has a crucial role in advancing systems modeling of molecular networks. However, due to the multidisciplinary techniques that are necessary for adaptation of such systems biology approaches, dissemination to a wide research community has been relatively slow. In this essay, I focus on some technical aspects that are often under-appreciated, yet critical in harnessing live cell imaging methods to achieve single-cell-level understanding and quantitative modeling of molecular networks. The importance of these technical considerations will be elaborated with examples of successes and shortcomings. Future efforts will benefit by avoiding some pitfalls and by utilizing the lessons collectively learned from recent applications of imaging in systems biology. PMID:24709701

  3. Progress Towards the Development of a Long-Lived Venus Lander Duplex System

    Science.gov (United States)

    Dyson, Rodger, W.; Bruder, Geoffrey A.

    2011-01-01

    NASA has begun the development of a combined Stirling cycle power and cooling system (duplex) to enable the long-lived surface exploration of Venus and other harsh environments in the solar system. The duplex system will operate from the heat provided by decaying radioisotope plutonium-238 or its substitute. Since the surface of Venus has a thick, hot, and corrosive atmosphere, it is a challenging proposition to maintain sensitive lander electronics under survivable conditions. This development effort requires the integration of: a radioisotope or fission heat source; heat pipes; high-temperature, corrosion-resistant material; multistage cooling; a novel free-displacer Stirling convertor for the lander; and a minimal vibration thermoacoustic Stirling convertor for the seismometer. The first year effort includes conceptual system design and control studies, materials development, and prototype hardware testing. A summary of these findings and test results is presented in this report.

  4. Extracting aerobic system dynamics during unsupervised activities of daily living using wearable sensor machine learning models.

    Science.gov (United States)

    Beltrame, Thomas; Amelard, Robert; Wong, Alexander; Hughson, Richard L

    2018-02-01

    Physical activity levels are related through algorithms to the energetic demand, with no information regarding the integrity of the multiple physiological systems involved in the energetic supply. Longitudinal analysis of the oxygen uptake (V̇o 2 ) by wearable sensors in realistic settings might permit development of a practical tool for the study of the longitudinal aerobic system dynamics (i.e., V̇o 2 kinetics). This study evaluated aerobic system dynamics based on predicted V̇o 2 data obtained from wearable sensors during unsupervised activities of daily living (μADL). Thirteen healthy men performed a laboratory-controlled moderate exercise protocol and were monitored for ≈6 h/day for 4 days (μADL data). Variables derived from hip accelerometer (ACC HIP ), heart rate monitor, and respiratory bands during μADL were extracted and processed by a validated random forest regression model to predict V̇o 2 . The aerobic system analysis was based on the frequency-domain analysis of ACC HIP and predicted V̇o 2 data obtained during μADL. Optimal samples for frequency domain analysis (constrained to ≤0.01 Hz) were selected when ACC HIP was higher than 0.05 g at a given frequency (i.e., participants were active). The temporal characteristics of predicted V̇o 2 data during μADL correlated with the temporal characteristics of measured V̇o 2 data during laboratory-controlled protocol ([Formula: see text] = 0.82, P system dynamics can be investigated during unsupervised activities of daily living by wearable sensors. Although speculative, these algorithms have the potential to be incorporated into wearable systems for early detection of changes in health status in realistic environments by detecting changes in aerobic response dynamics. NEW & NOTEWORTHY The early detection of subclinical aerobic system impairments might be indicative of impaired physiological reserves that impact the capacity for physical activity. This study is the first to use wearable

  5. Living technology: exploiting life's principles in technology.

    Science.gov (United States)

    Bedau, Mark A; McCaskill, John S; Packard, Norman H; Rasmussen, Steen

    2010-01-01

    The concept of living technology-that is, technology that is based on the powerful core features of life-is explained and illustrated with examples from artificial life software, reconfigurable and evolvable hardware, autonomously self-reproducing robots, chemical protocells, and hybrid electronic-chemical systems. We define primary (secondary) living technology according as key material components and core systems are not (are) derived from living organisms. Primary living technology is currently emerging, distinctive, and potentially powerful, motivating this review. We trace living technology's connections with artificial life (soft, hard, and wet), synthetic biology (top-down and bottom-up), and the convergence of nano-, bio-, information, and cognitive (NBIC) technologies. We end with a brief look at the social and ethical questions generated by the prospect of living technology.

  6. Liveness Redux: On Media and Their Claim to be Live

    NARCIS (Netherlands)

    van Es, K.F.

    2017-01-01

    Increasingly media are asserting themselves as live. In television, this has been an important strategy and recently it has been employed by new media platforms such as Facebook, Periscope and Snapchat. This commentary explains the revival of live media by exploring the meaning and operations of the

  7. Red photoluminescence of living systems at the room temperature: measurements and results

    International Nuclear Information System (INIS)

    Kudryashova, I S; Rud, V Yu; Shpunt, V Ch; Rud, Yu V; Glinushkin, A P

    2016-01-01

    Presents results of a study of the red luminescence of living plants at room temperature. The analysis of obtained results allows to conclude that the photoluminescence spectra for green leaves in all cases represent the two closely spaced bands. (paper)

  8. System architecture for ubiquitous live video streaming in university network environment

    CSIR Research Space (South Africa)

    Dludla, AG

    2013-09-01

    Full Text Available an architecture which supports ubiquitous live streaming for university or campus networks using a modified bluetooth inquiry mechanism with extended ID, integrated end-user device usage and adaptation to heterogeneous networks. Riding on that architecture...

  9. The living publication

    Energy Technology Data Exchange (ETDEWEB)

    Terwilliger, Thomas C. [Los Alamos National Laboratory

    2012-06-04

    Within the ICSTI Insights Series we offer three articles on the 'living publication' that is already available to practitioners in the important field of crystal structure determination and analysis. While the specific examples are drawn from this particular field, we invite readers to draw parallels in their own fields of interest. The first article describes the present state of the crystallographic living publication, already recognized by an ALPSP (Association of Learned and Professional Society Publishers) Award for Publishing Innovation in 2006. The second article describes the potential impact on the record of science as greater post-publication analysis becomes more common within currently accepted data deposition practices, using processed diffraction data as the starting point. The third article outlines a vision for the further improvement of crystallographic structure reports within potentially achievable enhanced data deposition practices, based upon raw (unprocessed) diffraction data. The IUCr in its Commissions and Journals has for many years emphasized the importance of publications being accompanied by data and the interpretation of the data in terms of atomic models. This has been followed as policy by numerous other journals in the field and its cognate disciplines. This practice has been well served by databases and archiving institutions such as the Protein Data Bank (PDB), the Cambridge Crystallographic Data Centre (CCDC), and the Inorganic Crystal Structure Database (ICSD). Normally the models that are archived are interpretations of the data, consisting of atomic coordinates with their displacement parameters, along with processed diffraction data from X-ray, neutron or electron diffraction studies. In our current online age, a reader can not only consult the printed word, but can display and explore the results with molecular graphics software of exceptional quality. Furthermore, the routine availability of processed diffraction

  10. The living publication

    International Nuclear Information System (INIS)

    Terwilliger, Thomas C.

    2012-01-01

    Within the ICSTI Insights Series we offer three articles on the 'living publication' that is already available to practitioners in the important field of crystal structure determination and analysis. While the specific examples are drawn from this particular field, we invite readers to draw parallels in their own fields of interest. The first article describes the present state of the crystallographic living publication, already recognized by an ALPSP (Association of Learned and Professional Society Publishers) Award for Publishing Innovation in 2006. The second article describes the potential impact on the record of science as greater post-publication analysis becomes more common within currently accepted data deposition practices, using processed diffraction data as the starting point. The third article outlines a vision for the further improvement of crystallographic structure reports within potentially achievable enhanced data deposition practices, based upon raw (unprocessed) diffraction data. The IUCr in its Commissions and Journals has for many years emphasized the importance of publications being accompanied by data and the interpretation of the data in terms of atomic models. This has been followed as policy by numerous other journals in the field and its cognate disciplines. This practice has been well served by databases and archiving institutions such as the Protein Data Bank (PDB), the Cambridge Crystallographic Data Centre (CCDC), and the Inorganic Crystal Structure Database (ICSD). Normally the models that are archived are interpretations of the data, consisting of atomic coordinates with their displacement parameters, along with processed diffraction data from X-ray, neutron or electron diffraction studies. In our current online age, a reader can not only consult the printed word, but can display and explore the results with molecular graphics software of exceptional quality. Furthermore, the routine availability of processed diffraction data allows

  11. Self-karaoke patterns: an interactive audio-visual system for handsfree live algorithm performance

    OpenAIRE

    Eldridge, Alice

    2014-01-01

    Self-karaoke Patterns, is an audiovisual study for improvised cello and live algorithms. The work is motivated in part by addressing the practical needs of the performer in ‘handsfree’ live algorithm contexts and in part an aesthetic concern with resolving the tension between conceptual dedication to autonomous algorithms and musical dedication to coherent performance. The elected approach is inspired by recent work investing the role of ‘shape’ in musical performance.

  12. Liveness redux: on media and their claim to be live.

    Science.gov (United States)

    van Es, Karin

    2017-11-01

    Increasingly media are asserting themselves as live. In television, this has been an important strategy and recently it has been employed by new media platforms such as Facebook, Periscope and Snapchat. This commentary explains the revival of live media by exploring the meaning and operations of the concept and argues the continued relevance of the concept for the study of social media. Traditionally, there have been three main approaches to the live in academic writing (i.e. liveness as ontology, as phenomenology and as rhetoric): each has its particular shortcoming. This paper proposes that it is more productive to understand the live as a construction that assists to secure media a central role in everyday life.

  13. Insulation measurement and supervision in live AC and DC unearthed systems

    CERN Document Server

    Olszowiec, Piotr

    2014-01-01

    Low voltage unearthed (IT) AC and DC systems are commonly applied for supply of power and control circuits in industry, transportation, medical objects etc. The main reasons for their use are high reliability and numerous advantages offered by isolating them against ground. Insulation level is a decisive factor for networks operational reliability and safety. Insufficient insulation-to-ground resistance can cause various disturbances. Though ground faults in IT systems do not make networks operation impossible, they may cause severe problems with their safe functioning. In this book the most important issues concerning normal operation and ground fault phenomena are described in concise form. Numerous methods of insulation resistance and capacitance measurement in live circuits are presented. Important other procedures of  these parameters determination based on measurement and calculation are explained and reviews of selected insulation resistance measurement devices as well as earth fault locating systems ...

  14. Insulation measurement and supervision in live AC and DC unearthed systems

    CERN Document Server

    Olszowiec, Piotr

    2013-01-01

    Low voltage unearthed (IT) AC and DC systems are commonly applied for supply of power and control circuits in industry, transportation, medical objects etc. The main reasons for their use are high reliability and numerous advantages offered by isolating them against ground. Insulation level is a decisive factor for networks operational reliability and safety. Insufficient insulation-to-ground resistance can cause various disturbances. Though ground faults in IT systems do not make networks operation impossible, they may cause severe problems with their safe functioning. In this book the most important issues concerning normal operation and ground fault phenomena are described in concise form. Numerous methods of insulation resistance and capacitance measurement in live circuits are presented. Important other procedures of  these parameters determination based on measurement and calculation are explained and reviews of selected insulation resistance measurement devices as well as earth fault locating systems ...

  15. Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths

    Directory of Open Access Journals (Sweden)

    Salinas Gustavo

    2010-04-01

    Full Text Available Abstract Background The thioredoxin and/or glutathione pathways occur in all organisms. They provide electrons for deoxyribonucleotide synthesis, function as antioxidant defenses, in detoxification, Fe/S biogenesis and participate in a variety of cellular processes. In contrast to their mammalian hosts, platyhelminth (flatworm parasites studied so far, lack conventional thioredoxin and glutathione systems. Instead, they possess a linked thioredoxin-glutathione system with the selenocysteine-containing enzyme thioredoxin glutathione reductase (TGR as the single redox hub that controls the overall redox homeostasis. TGR has been recently validated as a drug target for schistosomiasis and new drug leads targeting TGR have recently been identified for these platyhelminth infections that affect more than 200 million people and for which a single drug is currently available. Little is known regarding the genomic structure of flatworm TGRs, the expression of TGR variants and whether the absence of conventional thioredoxin and glutathione systems is a signature of the entire platyhelminth phylum. Results We examine platyhelminth genomes and transcriptomes and find that all platyhelminth parasites (from classes Cestoda and Trematoda conform to a biochemical scenario involving, exclusively, a selenium-dependent linked thioredoxin-glutathione system having TGR as a central redox hub. In contrast, the free-living platyhelminth Schmidtea mediterranea (Class Turbellaria possesses conventional and linked thioredoxin and glutathione systems. We identify TGR variants in Schistosoma spp. derived from a single gene, and demonstrate their expression. We also provide experimental evidence that alternative initiation of transcription and alternative transcript processing contribute to the generation of TGR variants in platyhelminth parasites. Conclusions Our results indicate that thioredoxin and glutathione pathways differ in parasitic and free-living flatworms and

  16. Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths

    Science.gov (United States)

    2010-01-01

    Background The thioredoxin and/or glutathione pathways occur in all organisms. They provide electrons for deoxyribonucleotide synthesis, function as antioxidant defenses, in detoxification, Fe/S biogenesis and participate in a variety of cellular processes. In contrast to their mammalian hosts, platyhelminth (flatworm) parasites studied so far, lack conventional thioredoxin and glutathione systems. Instead, they possess a linked thioredoxin-glutathione system with the selenocysteine-containing enzyme thioredoxin glutathione reductase (TGR) as the single redox hub that controls the overall redox homeostasis. TGR has been recently validated as a drug target for schistosomiasis and new drug leads targeting TGR have recently been identified for these platyhelminth infections that affect more than 200 million people and for which a single drug is currently available. Little is known regarding the genomic structure of flatworm TGRs, the expression of TGR variants and whether the absence of conventional thioredoxin and glutathione systems is a signature of the entire platyhelminth phylum. Results We examine platyhelminth genomes and transcriptomes and find that all platyhelminth parasites (from classes Cestoda and Trematoda) conform to a biochemical scenario involving, exclusively, a selenium-dependent linked thioredoxin-glutathione system having TGR as a central redox hub. In contrast, the free-living platyhelminth Schmidtea mediterranea (Class Turbellaria) possesses conventional and linked thioredoxin and glutathione systems. We identify TGR variants in Schistosoma spp. derived from a single gene, and demonstrate their expression. We also provide experimental evidence that alternative initiation of transcription and alternative transcript processing contribute to the generation of TGR variants in platyhelminth parasites. Conclusions Our results indicate that thioredoxin and glutathione pathways differ in parasitic and free-living flatworms and that canonical enzymes

  17. Short-lived radioactive nuclides in meteorites and early solar system processes

    International Nuclear Information System (INIS)

    Chaussidon, M.; Gounelle, M.

    2007-01-01

    Now extinct, short-lived radioactive nuclides, such as 7 Be (T 1/2 = 53 days), 10 Be (T 1/2 = 1.5 Ma), 26 Al (T 1/2 = 0.74 Ma), 36 Cl (T 1/2 = 0.3 Ma), 41 Ca (T 1/2 = 0.1 Ma), 53 Mn (T 1/2 = 3.7 Ma) and 60 Fe (T 1/2 = 1.5 Ma), were present in the proto-solar nebula when the various components of meteorites formed. The presence of these radioactive isotopes requires a 'last-minute' origin, either nucleosynthesis in a massive star dying close in space and time to the nascent solar system or production by local irradiation of part of the proto-solar disk by high-energy solar cosmic rays. In this review, we list: (i) the different observations indicating the existence of multiple origins for short-lived radioactive nuclides, namely 7 Be, 10 Be and 36 Cl for irradiation scenario and 60 Fe for injection scenario; (ii) the constraints that exist on their distribution (homogeneous or heterogeneous) in the accretion disk; (iii) the constraints they brought on the timescales of nebular processes (from Ca-Al-rich inclusions to chondrules) and of the accretion and differentiation of planetesimals. (authors)

  18. Model system for plant cell biology: GFP imaging in living onion epidermal cells

    Science.gov (United States)

    Scott, A.; Wyatt, S.; Tsou, P. L.; Robertson, D.; Allen, N. S.

    1999-01-01

    The ability to visualize organelle localization and dynamics is very useful in studying cellular physiological events. Until recently, this has been accomplished using a variety of staining methods. However, staining can give inaccurate information due to nonspecific staining, diffusion of the stain or through toxic effects. The ability to target green fluorescent protein (GFP) to various organelles allows for specific labeling of organelles in vivo. The disadvantages of GFP thus far have been the time and money involved in developing stable transformants or maintaining cell cultures for transient expression. In this paper, we present a rapid transient expression system using onion epidermal peels. We have localized GFP to various cellular compartments (including the cell wall) to illustrate the utility of this method and to visualize dynamics of these compartments. The onion epidermis has large, living, transparent cells in a monolayer, making them ideal for visualizing GFP. This method is easy and inexpensive, and it allows for testing of new GFP fusion proteins in a living tissue to determine deleterious effects and the ability to express before stable transformants are attempted.

  19. A Fluid Membrane-Based Soluble Ligand Display System for Live CellAssays

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Jwa-Min; Nair, Pradeep N.; Neve, Richard M.; Gray, Joe W.; Groves, Jay T.

    2005-10-14

    Cell communication modulates numerous biological processes including proliferation, apoptosis, motility, invasion and differentiation. Correspondingly, there has been significant interest in the development of surface display strategies for the presentation of signaling molecules to living cells. This effort has primarily focused on naturally surface-bound ligands, such as extracellular matrix components and cell membranes. Soluble ligands (e.g. growth factors and cytokines) play an important role in intercellular communications, and their display in a surface-bound format would be of great utility in the design of array-based live cell assays. Recently, several cell microarray systems that display cDNA, RNAi, or small molecules in a surface array format were proven to be useful in accelerating high-throughput functional genetic studies and screening therapeutic agents. These surface display methods provide a flexible platform for the systematic, combinatorial investigation of genes and small molecules affecting cellular processes and phenotypes of interest. In an analogous sense, it would be an important advance if one could display soluble signaling ligands in a surface assay format that allows for systematic, patterned presentation of soluble ligands to live cells. Such a technique would make it possible to examine cellular phenotypes of interest in a parallel format with soluble signaling ligands as one of the display parameters. Herein we report a ligand-modified fluid supported lipid bilayer (SLB) assay system that can be used to functionally display soluble ligands to cells in situ (Figure 1A). By displaying soluble ligands on a SLB surface, both solution behavior (the ability to become locally enriched by reaction-diffusion processes) and solid behavior (the ability to control the spatial location of the ligands in an open system) could be combined. The method reported herein benefits from the naturally fluid state of the supported membrane, which allows

  20. Clean by Nature. Lively Surfaces and the Holistic-Systemic Heritage of Contemporary Bionik.

    Directory of Open Access Journals (Sweden)

    Jan Mueggenburg

    2014-09-01

    Full Text Available This paper addresses questions regarding the prospering field of Bionik in Germany. Its starting point is the wide spread assumption that universal functional principles exist in nature and that these ‘solutions’ can be transferred into technological objects. Accordingly, advocates of Bionik herald the advent of a better world with more sustainable and efficient products of engineering. The so-called ‘functional surfaces’ occupy a special place within this contemporary version of biomimesis. Shark-skin-inspired swim suits, self-cleaning façade paints with lotus effect or drag reducing Dolphin-Skins for aircraft-wings are expected to improve the quality of life for everyone. It seems that skin and shell of living systems return as revenants to our technological world and live their afterlives as lively surfaces of everyday objects. This paper argues however, that understanding this attention to ‘natural engineering solutions’ in contemporary Bionik, one needs to focus on a different kind of afterlife. For baring the historic-epistemological roots allows fathoming direct connections to two widely influential historical concepts within the history of science in the 20th century: Biotechnik, a very popular bio-philosophical concept from the Weimar Republic of the 1920s and Bionics, an in many ways similar endeavor that emerged during the second wave of Cybernetics in the USA from around 1960. Both historical concepts share a certain proximity to a distinct holistic-systemic style of thinking that emerged during the 20th century and still resonates with the movement of Bionik in contemporary Germany. Based on the example of the lotus effect, I want to address three aspects of the afterlife of this holistic-systemic heritage in contemporary Bionik. First, the assumption that the best engineering solutions can be found in nature conceals the specific discursive and non-discursive complexity that forms the basis of all technological objects

  1. Development of an outdoor MRI system for measuring flow in a living tree

    Science.gov (United States)

    Nagata, Akiyoshi; Kose, Katsumi; Terada, Yasuhiko

    2016-04-01

    An outdoor MRI system for noninvasive, long-term measurements of sap flow in a living tree in its natural environment has been developed. An open-access, 0.2 T permanent magnet with a 160 mm gap was combined with a radiofrequency probe, planar gradient coils, electromagnetic shielding, several electrical units, and a waterproofing box. Two-dimensional cross-sectional images were acquired for a ring-porous tree, and the anatomical structures, including xylem and phloem, were identified. The MRI flow measurements demonstrated the diurnal changes in flow velocity in the stem on a per-pixel basis. These results demonstrate that our outdoor MRI system is a powerful tool for studies of water transport in outdoor trees.

  2. The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems.

    Science.gov (United States)

    Su, Tsung-Ping; Su, Tzu-Chieh; Nakamura, Yoki; Tsai, Shang-Yi

    2016-04-01

    The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum (ER) protein that resides specifically in the mitochondria-associated endoplasmic reticulum (ER) membrane (MAM), an interface between ER and mitochondria. In addition to being able to translocate to the plasma membrane (PM) to interact with ion channels and other receptors, Sig-1R also occurs at the nuclear envelope, where it recruits chromatin-remodeling factors to affect the transcription of genes. Sig-1Rs have also been reported to interact with other membranous or soluble proteins at other loci, including the cytosol, and to be involved in several central nervous system (CNS) diseases. Here, we propose that Sig-1R is a pluripotent modulator with resultant multiple functional manifestations in living systems. Published by Elsevier Ltd.

  3. Introduction: Teaching Black Lives Matter

    OpenAIRE

    Paula Austin; Erica Cardwell; Christopher Kennedy; Robyn Spencer

    2016-01-01

    An introduction to Radical Teacher, Issue 106: Teaching Black Lives Matter. This issue brings together a diverse collection of articles exploring educator’s responses, strategies, and stories on how #BlackLivesMatter has informed their teaching practice, the content of their courses, and their personal relationship to colleagues, family, friends, and self.

  4. Introduction: Teaching Black Lives Matter

    Directory of Open Access Journals (Sweden)

    Paula Austin

    2016-11-01

    Full Text Available An introduction to Radical Teacher, Issue 106: Teaching Black Lives Matter. This issue brings together a diverse collection of articles exploring educator’s responses, strategies, and stories on how #BlackLivesMatter has informed their teaching practice, the content of their courses, and their personal relationship to colleagues, family, friends, and self.

  5. Community Living Skills Guide: Art.

    Science.gov (United States)

    Sobol, Sheila; Kreps, Alice Roelofs

    One of twenty course guides in the Community Living Skills Guide for the College for Living series, this document provides guidelines and workbook activities for the course, Art. The series of courses for developmentally disabled adults is intended to supplement residential programs and to aid in orienting institutionalized persons to eventual…

  6. Systems thinking in 49 communities related to healthy eating, active living, and childhood obesity.

    Science.gov (United States)

    Brennan, Laura K; Sabounchi, Nasim S; Kemner, Allison L; Hovmand, Peter

    2015-01-01

    Community partnerships to promote healthy eating and active living in order to prevent childhood obesity face a number of challenges. Systems science tools combined with group model-building techniques offer promising methods that use transdisciplinary team-based approaches to improve understanding of the complexity of the obesity epidemic. This article presents evaluation methods and findings from 49 Healthy Kids, Healthy Communities sites funded to implement policy, system, and environmental changes from 2008 to 2014. Through half-day group model-building sessions conducted as part of evaluation site visits to each community between 2010 and 2013, a total of 50 causal loop diagrams were produced for 49 communities (1 community had 2 causal loop diagrams representing different geographic regions). The analysis focused on the following evaluation questions: (1) What were the most prominent variables in the causal loop diagrams across communities? (2) What were the major feedback structures across communities? (3) What implications from the synthesized causal loop diagram can be translated to policy makers, practitioners, evaluators, funders, and other community representatives? A total of 590 individuals participated with an average of 12 participants per session. Participants' causal loop diagrams included a total of 227 unique variables in the following major subsystems: healthy eating policies and environments, active living policies and environments, health and health behaviors, partnership and community capacity, and social determinants. In a synthesized causal loop diagram representing variables identified by at least 20% of the communities, many feedback structures emerged and several themes are highlighted with respect to implications for policy and practice as well as assessment and evaluation. The application of systems thinking tools combined with group model-building techniques creates opportunities to define and characterize complex systems in a manner

  7. Living alone and activation of the renin-angiotensin-aldosterone-system: Differential effects depending on alexithymic personality features.

    Science.gov (United States)

    Terock, Jan; Hannemann, Anke; Janowitz, Deborah; Völzke, Henry; Nauck, Matthias; Freyberger, Harald-Jürgen; Wallaschofski, Henri; Grabe, Hans Jörgen

    2017-05-01

    Living alone is considered as a chronic stress factor predicting different health conditions and particularly cardiovascular disease (CVD). Alexithymia is associated with increased psychological distress, less social skills and fewer close relationships, making alexithymic subjects particularly susceptible to chronic stress imposed by "living alone". Only few studies investigated the renin-angiotensin-aldosterone-system (RAAS) activity in response to chronic stress. We aimed at evaluating the effects of "living alone" as a paradigm for chronic stress on RAAS activity and putatively differential effects depending on alexithymic personality features. Alexithymia and serum concentrations of renin and aldosterone were measured in 944 subjects from the population-based SHIP-1 study. Subgroups were formed using the median of the Toronto Alexithymia Scale-20 (TAS-20) and a cohabitation status of "living alone" or "living together". Analyses were adjusted for various psychosocial, behavioral and metabolic risk factors. "Living alone" was associated with elevated plasma renin (p<0.01, β=0.138) but not aldosterone concentrations in the total sample. On subgroup level, we found associations of "living alone" and elevated renin concentrations only in subjects low in TAS-20 scores (p<0.01, β=0.219). Interactional effects of alexithymia×cohabitation status were found for the aldosterone-to-renin ratio (p=0.02, β=-0.234). The association of chronic stress imposed by "living alone" with increased RAAS activity contributes to explain the relationship of this psychosocial stress condition and increased risk for CVD. In contrast, alexithymic subjects may be less affected by the deleterious effects of "living alone". Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Solo Living - the meaning of home for persons living alone

    DEFF Research Database (Denmark)

    Christensen, Toke Haunstrup

    observed. Firstly, solo livers emphasize independence from others as important. Several of the informants have had negative experiences with living together with a partner, and they like the feeling of being independent. At the same time, most informants also keep a door open for the possibility of moving...... together with "the right one", which indicates that ambiguity is related to the situation of solo living. Secondly, some of the solo livers spend more time outside home (occupied by leisure activities or together with friends) compared to people living in family households in general, which suggests...... a different balance between time at home and outside home for some solo livers....

  9. Effect of long-lived containers on the postclosure performance of a reference disposal system

    International Nuclear Information System (INIS)

    Goodwin, B.W.; Hajas, W.C.; LeNeveu, D.M.

    1996-05-01

    The concept for disposal of Canada's nuclear fuel waste involves isolating the waste in corrosion-resistant containers emplaced in a scaled vault at a depth of 500 to 1000 m in plutonic rock of the Canadian Shield. The concept permits a choice of methods, materials, site locations, and designs. The technical feasibility of this concept and its impact on the environment and human health are summarized in an Environmental Impact Statement (AECL 1994a,b), supported by nine detailed reference documents (Davis et al. 1993; Davison et al. 1994a,b; Goodwin et al. 1994; Greber et al. 1994; Grondin et al. 1994; Johnson et al. 1994a,b; Simmons and Baumgartner 1994). In the assessment of the reference disposal system, we assumed the containers encapsulating the nuclear fuel waste were constructed from Grade-2 titanium. In this report, we investigate the effect of a different choice, and assume the use of long-lived containers constructed from materials such as high-purity copper or Grades-12 or -16 titanium alloys. These alternative materials would provide much longer periods of protection, based on the expectation that the only container failure mechanism, for times up to 10 5 a, involves initial fabrication defects. We explore the effects of long-lived containers for the same vault layout and orientation that were assumed for the reference disposal vault. We also explore effects for two less favourable situations, in which the vault is closer to a nearby fracture zone and in which the vault is extended to have emplacement rooms on both sides of the fracture zone. Our analyses use the probabilistic assessment computer code, SYVAC3-CC3, an acronym for SYstems Variability Analysis Code, generation 3. with a system model describing the Canadian Concept, generation 3, for the disposal of nuclear fuel waste. The input data for the code have been adjusted to approximate the expected protection characteristics of alternative container materials. (author). 31 refs., 1 tab., 16 figs

  10. Food system access, shopping behavior, and influences on purchasing groceries in adult Hmong living in Minnesota.

    Science.gov (United States)

    Franzen, Lisa; Smith, Chery

    2010-01-01

    To investigate influences on shopping and eating behavior of Hmong adults living in St. Paul/Minneapolis, Minnesota. Conducted a mapping project, food surveys, food frequency questionnaire (FFQ), and focus groups (n = 11). Subjects were assigned to three groups. The B-TL(1) group was made up of subjects who were born in Thailand/Laos and had lived in the US 5 years (n = 20). The B-US group was made up of subjects who were born and/or raised in the US (n = 30). Using Geographical Informational Systems software, 15 grocery stores were mapped and surveyed. Food prices were compared with the consumer price index (CPI). The FFQ assessed food consumption patterns. Focus group transcripts were evaluated for themes and coded. Degree of acculturation was assessed by adapting a previously developed instrument. The population is concentrated in St. Paul, coinciding with store density. Limited foods had CPIs and some CPIs were outdated. B-US had significantly higher levels of dietary acculturation than B-TL(2) and B-TL(1), with B-TL(2) also having a higher dietary acculturation level compared with B-TL(1). Acculturation of the Hmong into the American food system, determinants of store type, and Hmong food's having a mainstream factor were identified themes. B-US and B-TL(2) shopped at American stores more than did B-TL(1) because of convenience, one-stop shopping, and increased English fluency. Hmong foods have entered the American food system and are sold at Asian and American stores.

  11. Evaluation of a Smartphone-based Human Activity Recognition System in a Daily Living Environment.

    Science.gov (United States)

    Lemaire, Edward D; Tundo, Marco D; Baddour, Natalie

    2015-12-11

    An evaluation method that includes continuous activities in a daily-living environment was developed for Wearable Mobility Monitoring Systems (WMMS) that attempt to recognize user activities. Participants performed a pre-determined set of daily living actions within a continuous test circuit that included mobility activities (walking, standing, sitting, lying, ascending/descending stairs), daily living tasks (combing hair, brushing teeth, preparing food, eating, washing dishes), and subtle environment changes (opening doors, using an elevator, walking on inclines, traversing staircase landings, walking outdoors). To evaluate WMMS performance on this circuit, fifteen able-bodied participants completed the tasks while wearing a smartphone at their right front pelvis. The WMMS application used smartphone accelerometer and gyroscope signals to classify activity states. A gold standard comparison data set was created by video-recording each trial and manually logging activity onset times. Gold standard and WMMS data were analyzed offline. Three classification sets were calculated for each circuit: (i) mobility or immobility, ii) sit, stand, lie, or walking, and (iii) sit, stand, lie, walking, climbing stairs, or small standing movement. Sensitivities, specificities, and F-Scores for activity categorization and changes-of-state were calculated. The mobile versus immobile classification set had a sensitivity of 86.30% ± 7.2% and specificity of 98.96% ± 0.6%, while the second prediction set had a sensitivity of 88.35% ± 7.80% and specificity of 98.51% ± 0.62%. For the third classification set, sensitivity was 84.92% ± 6.38% and specificity was 98.17 ± 0.62. F1 scores for the first, second and third classification sets were 86.17 ± 6.3, 80.19 ± 6.36, and 78.42 ± 5.96, respectively. This demonstrates that WMMS performance depends on the evaluation protocol in addition to the algorithms. The demonstrated protocol can be used and tailored for evaluating human activity

  12. Rate of recovery from perturbations as a means to forecast future stability of living systems.

    Science.gov (United States)

    Ghadami, Amin; Gourgou, Eleni; Epureanu, Bogdan I

    2018-06-18

    Anticipating critical transitions in complex ecological and living systems is an important need because it is often difficult to restore a system to its pre-transition state once the transition occurs. Recent studies demonstrate that several indicators based on changes in ecological time series can indicate that the system is approaching an impending transition. An exciting question is, however, whether we can predict more characteristics of the future system stability using measurements taken away from the transition. We address this question by introducing a model-less forecasting method to forecast catastrophic transition of an experimental ecological system. The experiment is based on the dynamics of a yeast population, which is known to exhibit a catastrophic transition as the environment deteriorates. By measuring the system's response to perturbations prior to transition, we forecast the distance to the upcoming transition, the type of the transition (i.e., catastrophic/non-catastrophic) and the future equilibrium points within a range near the transition. Experimental results suggest a strong potential for practical applicability of this approach for ecological systems which are at risk of catastrophic transitions, where there is a pressing need for information about upcoming thresholds.

  13. From Patterns to Function in Living Systems: Dryland Ecosystems as a Case Study

    Science.gov (United States)

    Meron, Ehud

    2018-03-01

    Spatial patterns are ubiquitous in animate matter. Besides their intricate structure and beauty they generally play functional roles. The capacity of living systems to remain functional in changing environments is a question of utmost importance, but its intimate relationship to pattern formation is largely unexplored. Here, we address this relationship using dryland vegetation as a case study. Following a brief introduction to pattern-formation theory, we describe a mathematical model that captures several mechanisms of vegetation pattern formation and discuss ecological contexts that showcase different mechanisms. Using this model, we unravel the different vegetation patterns that keep dryland ecosystems viable along the rainfall gradient, identify multistability ranges where fronts separating domains of alternative stable states exist, and highlight the roles of front dynamics in mitigating or reversing desertification. The utility of satellite images in testing model predictions is discussed. An outlook on outstanding open problems concludes this paper.

  14. A Complexity-Aware Video Adaptation Mechanism for Live Streaming Systems

    Directory of Open Access Journals (Sweden)

    Chen Homer H

    2007-01-01

    Full Text Available The paradigm shift of network design from performance-centric to constraint-centric has called for new signal processing techniques to deal with various aspects of resource-constrained communication and networking. In this paper, we consider the computational constraints of a multimedia communication system and propose a video adaptation mechanism for live video streaming of multiple channels. The video adaptation mechanism includes three salient features. First, it adjusts the computational resource of the streaming server block by block to provide a fine control of the encoding complexity. Second, as far as we know, it is the first mechanism to allocate the computational resource to multiple channels. Third, it utilizes a complexity-distortion model to determine the optimal coding parameter values to achieve global optimization. These techniques constitute the basic building blocks for a successful application of wireless and Internet video to digital home, surveillance, IPTV, and online games.

  15. A Complexity-Aware Video Adaptation Mechanism for Live Streaming Systems

    Science.gov (United States)

    Lu, Meng-Ting; Yao, Jason J.; Chen, Homer H.

    2007-12-01

    The paradigm shift of network design from performance-centric to constraint-centric has called for new signal processing techniques to deal with various aspects of resource-constrained communication and networking. In this paper, we consider the computational constraints of a multimedia communication system and propose a video adaptation mechanism for live video streaming of multiple channels. The video adaptation mechanism includes three salient features. First, it adjusts the computational resource of the streaming server block by block to provide a fine control of the encoding complexity. Second, as far as we know, it is the first mechanism to allocate the computational resource to multiple channels. Third, it utilizes a complexity-distortion model to determine the optimal coding parameter values to achieve global optimization. These techniques constitute the basic building blocks for a successful application of wireless and Internet video to digital home, surveillance, IPTV, and online games.

  16. Sigma-1 Receptor as a Pluripotent Modulator in the Living System

    Science.gov (United States)

    Su, Tsung-Ping; Su, Tzu-Chieh; Nakamura, Yoki; Tsai, Shang-Yi

    2016-01-01

    The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum (ER) protein resides specifically at the interface between ER and mitochondria, called the MAM, where the Sig-1R is recently reported to be involved in certain CNS diseases. In addition to being able to translocate to the plasma membrane to interact with ion channels and other receptors, the Sig-1R is found to exist at the nuclear envelope where it recruits chromatin-remodeling factors to affect the transcription of genes. As well, thorough experimental and bioinformatic means, Sig-1Rs are reported to interact with other membranous or soluble proteins at other loci, including the cytosol. We propose that the Sig-1R is a pluripotent modulator with resultant multiple functional manifestations in the living system. PMID:26869505

  17. External tandem target system for efficient production of short-lived positron emitting radionuclides

    International Nuclear Information System (INIS)

    Koh, K.; Dwyer, J.; Finn, R.; Sheh, Y.; Sinnreich, J.; Wooten, T.

    1983-01-01

    Recent developments in radiopharmaceutical chemistry allow the incorporation of short-lived, positron-emitting radionuclides into a variety of compounds which when used with a positron emission tomograph provide a means of monitoring physiological disorders by a standard technique. To effectively meet the increased ''in-house'' clinical demands while maintaining a production schedule, a tandem target was designed and has been installed for the simultaneous ''on-line'' preparation of oxygen-15 labelled compounds such as CO 2 15 , H 2 O 15 ; and nitrogen-13 labelled compounds such as 13 NH 3 , 13 N 2 O, and 13 N 2 . The processing time required for the synthesis of the nitrogen-13 products as compared to the essentially instantaneous formation of oxygen-15 labelled compounds has provided the necessary time delay for clinical utilization. The characterisitcs of this external tandem target system as well as the automation for the dual processing are presented

  18. Living labs design and assessment of sustainable living

    CERN Document Server

    Guerra-Santin, Olivia; Lockton, Dan

    2017-01-01

    This book presents the results of a multi-annual project with sustainable Living Labs in the United Kingdom, Sweden, Germany and the Netherlands. Living Labs – as initiated by the authors – have proved to be very promising research, design, co-creation and communication facilities for the development and implementation of sustainable innovations in the home. The book provides an inspiring introduction to both the methodology and business modelling for the Living Lab facilities. Understanding daily living at home is key to designing products and services that support households in their transition to more sustainable lifestyles. This book not only explores new ways of gaining insights into daily practices, but also discusses developing and testing design methods to create sustainable solutions for households. These new methods and tools are needed because those available are either ineffective or cause rebound-effects. Intended for researchers and designers with an interest in the transition to sustainable...

  19. LiveCode mobile development

    CERN Document Server

    Lavieri, Edward D

    2013-01-01

    A practical guide written in a tutorial-style, ""LiveCode Mobile Development Hotshot"" walks you step-by-step through 10 individual projects. Every project is divided into sub tasks to make learning more organized and easy to follow along with explanations, diagrams, screenshots, and downloadable material.This book is great for anyone who wants to develop mobile applications using LiveCode. You should be familiar with LiveCode and have access to a smartphone. You are not expected to know how to create graphics or audio clips.

  20. Synthetic approaches towards new polymer systems by the combination of living carbocationic and anionic polymerizations

    DEFF Research Database (Denmark)

    Feldthusen, Jesper; Ivan, Bela; Muller, Axel. H.E.

    1996-01-01

    Recent efforts to obtain block copolymers by combination of living carbocationic and anionic polymerizations are presented.When tolyl-ended polyisobutylene was used as macroinitiator of anionic polymerization of methacrylate derivatives mixtures of homopolymers and block copolymers were formed due...... to incomplete lithiation of this chain end.In another approach a new functionalization method was developed by end-quenching living polyisobutylene with 1,1-diphenylethylene. After transformation of the groups into 2,2-diphenylvinyl end groups and lithiation polymers were synthesized from protected acrylate...

  1. Active in-database processing to support ambient assisted living systems.

    Science.gov (United States)

    de Morais, Wagner O; Lundström, Jens; Wickström, Nicholas

    2014-08-12

    As an alternative to the existing software architectures that underpin the development of smart homes and ambient assisted living (AAL) systems, this work presents a database-centric architecture that takes advantage of active databases and in-database processing. Current platforms supporting AAL systems use database management systems (DBMSs) exclusively for data storage. Active databases employ database triggers to detect and react to events taking place inside or outside of the database. DBMSs can be extended with stored procedures and functions that enable in-database processing. This means that the data processing is integrated and performed within the DBMS. The feasibility and flexibility of the proposed approach were demonstrated with the implementation of three distinct AAL services. The active database was used to detect bed-exits and to discover common room transitions and deviations during the night. In-database machine learning methods were used to model early night behaviors. Consequently, active in-database processing avoids transferring sensitive data outside the database, and this improves performance, security and privacy. Furthermore, centralizing the computation into the DBMS facilitates code reuse, adaptation and maintenance. These are important system properties that take into account the evolving heterogeneity of users, their needs and the devices that are characteristic of smart homes and AAL systems. Therefore, DBMSs can provide capabilities to address requirements for scalability, security, privacy, dependability and personalization in applications of smart environments in healthcare.

  2. In defense of a regulated system of compensation for living donation.

    Science.gov (United States)

    Matas, Arthur J; Hippen, Benjamin; Satel, Sally

    2008-08-01

    The organ shortage is the major problem in kidney transplantation today. Despite aggressive organ procurement efforts, the supply of donated kidneys, living and deceased, has not matched the growing demand; as a consequence, more and more qualified candidates are suffering on dialysis and then dying before being transplanted. Herein, we provide justification for a regulated system of compensation for donation. The main argument in favor of compensation is simple-financial incentives will increase donation, so fewer transplant candidates will suffer and die while waiting. In addition, development of a regulated system of compensation is the most effective means of crippling the core economic support for transplant tourism. Because dialysis is so much more expensive than a transplant, compensated donation could be cost-neutral to the healthcare system. Importantly, opinion polls suggest that the public would support compensation. As uncompensated kidney donation is widely accepted, persuasive arguments against compensation must explain why such a system would be morally distinguishable from uncompensated donation. We suggest that the potential advantages of a regulated system of compensation for donation far outweigh any potential disadvantages. It is time to advocate for a change in the law so that trials can be done.

  3. Active In-Database Processing to Support Ambient Assisted Living Systems

    Directory of Open Access Journals (Sweden)

    Wagner O. de Morais

    2014-08-01

    Full Text Available As an alternative to the existing software architectures that underpin the development of smart homes and ambient assisted living (AAL systems, this work presents a database-centric architecture that takes advantage of active databases and in-database processing. Current platforms supporting AAL systems use database management systems (DBMSs exclusively for data storage. Active databases employ database triggers to detect and react to events taking place inside or outside of the database. DBMSs can be extended with stored procedures and functions that enable in-database processing. This means that the data processing is integrated and performed within the DBMS. The feasibility and flexibility of the proposed approach were demonstrated with the implementation of three distinct AAL services. The active database was used to detect bed-exits and to discover common room transitions and deviations during the night. In-database machine learning methods were used to model early night behaviors. Consequently, active in-database processing avoids transferring sensitive data outside the database, and this improves performance, security and privacy. Furthermore, centralizing the computation into the DBMS facilitates code reuse, adaptation and maintenance. These are important system properties that take into account the evolving heterogeneity of users, their needs and the devices that are characteristic of smart homes and AAL systems. Therefore, DBMSs can provide capabilities to address requirements for scalability, security, privacy, dependability and personalization in applications of smart environments in healthcare.

  4. Stochastic control of living systems: Normalization of physiological functions by magnetic field with 1/f power spectrum

    Science.gov (United States)

    Muzalevskaya, N. I.; Uritsky, V. M.; Korolyov, E. V.; Reschikov, A. M.; Timoshinov, G. P.

    1993-08-01

    For the first time correcting stochastic control of physiological status of living systems by weak low-frequency fluctuating magnetic field with 1/f spectrum (1/f MF) is demonstrated experimentally. The correction was observed in all main systems, including cardiovascular, central nervous, immunity systems of experimental animals. Pronounced prophylactic and therapeutic influence of 1/f MF on malignant growth and radiation disease was discovered. Theoretical interpretation of the results obtained is based upon the notion of fundamental role of 1/f fluctuations in homeostasis of living systems.

  5. Genetically-encoded tools for cAMP probing and modulation in living systems.

    Directory of Open Access Journals (Sweden)

    Valeriy M Paramonov

    2015-09-01

    Full Text Available Intracellular 3'-5'-cyclic adenosine monophosphate (cAMP is one of the principal second messengers downstream of a manifold of signal transduction pathways, including the ones triggered by G protein-coupled receptors. Not surprisingly, biochemical assays for cAMP have been instrumental for basic research and drug discovery for decades, providing insights into cellular physiology and guiding pharmaceutical industry. However, despite impressive track record, the majority of conventional biochemical tools for cAMP probing share the same fundamental shortcoming - all the measurements require sample disruption for cAMP liberation. This common bottleneck, together with inherently low spatial resolution of measurements (as cAMP is typically analyzed in lysates of thousands of cells, underpin the ensuing limitations of the conventional cAMP assays: 1 genuine kinetic measurements of cAMP levels over time in a single given sample are unfeasible; 2 inability to obtain precise information on cAMP spatial distribution and transfer at subcellular levels, let alone the attempts to pinpoint dynamic interactions of cAMP and its effectors. At the same time, tremendous progress in synthetic biology over the recent years culminated in drastic refinement of our toolbox, allowing us not only to bypass the limitations of conventional assays, but to put intracellular cAMP life-span under tight control – something, that seemed scarcely attainable before. In this review article we discuss the main classes of modern genetically-encoded tools tailored for cAMP probing and modulation in living systems. We examine the capabilities and weaknesses of these different tools in the context of their operational characteristics and applicability to various experimental set-ups involving living cells, providing the guidance for rational selection of the best tools for particular needs.

  6. Experiences and perspectives of adults living with systemic lupus erythematosus: thematic synthesis of qualitative studies.

    Science.gov (United States)

    Sutanto, Bernadet; Singh-Grewal, Davinder; McNeil, H Patrick; O'Neill, Sean; Craig, Jonathan C; Jones, Julie; Tong, Allison

    2013-11-01

    Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that significantly impairs patients’ quality of life and can be life threatening. This study aimed to describe the experiences and perspectives of adults living with SLE. We conducted a systematic review and thematic synthesis of qualitative studies that explored the experiences of adults living with SLE. We searched MEDLINE, Embase, PsycINFO, CINAHL (to November week 1, 2012), Google Scholar, a thesis database, and reference lists of relevant articles. Forty-six studies involving 1,385 participants were included. Five themes were identified: restricted lifestyle(including subthemes of pervasive pain, debilitating fatigue, mental deterioration, disruptive episodic symptoms, and postponing parenthood), disrupted identity (gaining diagnostic closure, prognostic uncertainty, being a burden, hopelessness, heightened self-consciousness, fearing rejection, and guilt and punishment), societal stigma and indifference(illness trivialization, socially ostracized, and averse to differential treatment), gaining resilience (optimism, control and empowerment, being informed and involved, and valuing mutual understanding), and treatment adherence (preserving health, rapport with clinicians, negotiating medication regimens, and financial burden). SLE has a severe and pervasive impact on patients’ self-esteem and independence. Their physical and social functioning is limited and they feel anxious about their future. Patients perceive that SLE is trivialized, misunderstood,and stigmatized by their family, friends, and physicians, which intensifies their sense of isolation. Educational, psychosocial, and self-care interventions are needed to promote mental resilience, positive coping strategies, self-advocacy, and capacities for social participation, and thereby to achieve better treatment and health outcomes in patients with SLE.

  7. Toward a low-cost gait analysis system for clinical and free-living assessment.

    Science.gov (United States)

    Ladha, Cassim; Del Din, Silvia; Nazarpour, Kianoush; Hickey, Aodhan; Morris, Rosie; Catt, Michael; Rochester, Lynn; Godfrey, Alan

    2016-08-01

    Gait is an important clinical assessment tool since changes in gait may reflect changes in general health. Measurement of gait is a complex process which has been restricted to bespoke clinical facilities until recently. The use of inexpensive wearable technologies is an attractive alternative and offers the potential to assess gait in any environment. In this paper we present the development of a low cost analysis gait system built using entirely open source components. The system is used to capture spatio-temporal gait characteristics derived from an existing conceptual model, sensitive to ageing and neurodegenerative pathology (e.g. Parkinson's disease). We demonstrate the system is suitable for use in a clinical unit and will lead to pragmatic use in a free-living (home) environment. The system consists of a wearable (tri-axial accelerometer and gyroscope) with a Raspberry Pi module for data storage and analysis. This forms ongoing work to develop gait as a low cost diagnostic in modern healthcare.

  8. The Systemic Theory of Living Systems. Part IV: Systemic Medicine—The Praxis

    Directory of Open Access Journals (Sweden)

    José A. Olalde Rangel

    2005-01-01

    Full Text Available This fourth lecture illustrates the praxis and results of Systemic Medicine (SM in various therapeutic applications. SM's success has made it popular throughout Venezuela and Puerto Rico. The treatment of over 300 000 patients by 150 orthodox MD's, trained and qualified in SM, in 35 medical establishments with above average results corroborate its effectiveness as an eCAM in chronic degenerative diseases. Herein we provide a synopsis of results obtained in four such pathologies—the journal's necessary space restrictions somewhat limiting content—as well as clinical and photographic evidence. The validity of any medical theory is substantiated by its degree of effectivity and success. The workability of evidence-based SM corroborates Systemic Theory's transcendence.

  9. Living with HIV: Patients Perspective

    Centers for Disease Control (CDC) Podcasts

    This podcast showcases three people who are living with HIV. The patients share their experiences of being diagnosed with HIV, of the treatments they are undergoing, and on taking responsibility for their health.

  10. Advanced Melanoma Facebook Live Event

    Science.gov (United States)

    In case you missed it, watch this recent Facebook Live event about the current state of research and treatment for advanced stage melanoma. To learn more, see our evidence-based information about skin cancer, including melanoma.

  11. Disability and Health: Healthy Living

    Science.gov (United States)

    ... About CDC.gov . Disability & Health Home Disability Overview Disability Inclusion Barriers to Inclusion Inclusion Strategies Inclusion in Programs & Activities Resources Healthy Living Disability & Physical Activity Disability & Obesity Disability & Smoking Disability & Breast ...

  12. History: A Great Lives Approach

    Science.gov (United States)

    Jarvis, F. Washington

    1973-01-01

    After examining the drawbacks of some of the currently popular teaching methods, the author proposes an approach to the teaching of high school history focusing on the matter of history -- the lives of men and ideas of the past. (SM)

  13. Living with a Single Parent

    Science.gov (United States)

    ... kids in the United States live with one parent. Separation and divorce are the most common reasons for ... Who Are Moving Should Do What Is a Divorce? Getting Along With Parents Going to a Therapist View more About Us ...

  14. Walking and Sensing Mobile Lives

    DEFF Research Database (Denmark)

    Bødker, Mads; Meinhardt, Nina Dam

    In this position paper, we discuss how mindful walking with people allow us to explore sensory aspects of mobile lives that are typically absent from research. We present an app that aids researchers collect impressions from a walk.......In this position paper, we discuss how mindful walking with people allow us to explore sensory aspects of mobile lives that are typically absent from research. We present an app that aids researchers collect impressions from a walk....

  15. Living antennas on communication satellites

    DEFF Research Database (Denmark)

    Lumholt, Michael

    2003-01-01

    Crises change the global pattern of communication. The communications problems occur because the satellites are optimized to cover specific geographic areas, and these areas cannot be altered once the satellites are in Earth orbit. An effective solution to the problem is to equip communication sa...... satellites with "living" antennas that can adjust their radiation coverage areas according to the new demands. The development of living antennas is, therefore, among the focus areas identified and supported by the European Space Agency, ESA....

  16. Ambient Assisted Living Systems in the Context of Human Centric Sensing and IoT Concept

    DEFF Research Database (Denmark)

    Zaric, Nicola; Pejanovic-Djurisic, Milica; Mihovska, Albena Dimitrova

    2016-01-01

    This paper proposes the concept of Human Centric Sensing in the context of Internet of Things and Ambient Assisted Living. The paper uses a case study to present and analyze the proposed idea, and identifies the main challenges and open issues that require research and policy attention....

  17. [Passive euthanasia and living will].

    Science.gov (United States)

    Julesz, Máté

    2014-07-06

    This article deals with the intentional distinction between murder of first degree and passive euthanasia. In Hungary, active euthanasia is considered to be a murder of first degree, whilst the Netherlands, Belgium, Luxemburg and Switzerland have legalized the active form of mercy killing in Europe. The palliative terminal care, when e.g. giving pain-killer morphine to the patient, might result in decreasing the patient's life-span, and thus causing indirect euthanasia. However, the legal institution of living will exists in several counter-euthanasia countries. The living will allows future patients to express their decision in advance to refuse a life-sustaining treatment, e.g. in case of irreversible coma. The institution of living will exists in Germany and in Hungary too. Nevertheless, the formal criteria of living will make it hardly applicable. The patient ought to express his/her will before a notary public in advance, and he/she should hand it over when being hospitalized. If the patient is not able to present his/her living will to his/her doctor in the hospital, then his/her only hope remains that he/she has given a copy of the living will to the family doctor previously, and the family doctor will notify the hospital.

  18. Study on risk-based operation and maintenance using the living PSA system

    International Nuclear Information System (INIS)

    Kurisaka, K.

    2000-01-01

    The objective of this study is to contribute to an improvement of fast reactor plant operation and maintenance from the standpoint of risk assessment. An effort was made to analyze a relationship between the valve failure probability and the standby time based on the component reliability database and statistical analysis system (CORDS). According to the analysis result, the following issues were examined: the surveillance test interval (STI), timing and the allowable outage time (AOT) of redundant valve system in a fast reactor model plant. An examination was performed based on the failure probability non-linearly dependent on the standby time using the risk importance measures and technique to optimize the AOT which are incorporated in the living PSA system (LIPSAS). The case study showed that consideration of non-linear time trend of the failure probability made the recommended STI and AOT longer under the same risk limitation. It is recommended to apply the nonlinear expression of demand failure probability in estimating the STI and AOT based on the risk measures. (author)

  19. Hands-On Experiences in Deploying Cost-Effective Ambient-Assisted Living Systems.

    Science.gov (United States)

    Dasios, Athanasios; Gavalas, Damianos; Pantziou, Grammati; Konstantopoulos, Charalampos

    2015-06-18

    Older adults' preferences to remain independent in their own homes along with the high costs of nursing home care have motivated the development of Ambient Assisted Living (AAL) technologies which aim at improving the safety, health conditions and wellness of the elderly. This paper reports hands-on experiences in designing, implementing and operating UbiCare, an AAL based prototype system for elderly home care monitoring. The monitoring is based on the recording of environmental parameters like temperature and light intensity as well as micro-level incidents which allows one to infer daily activities like moving, sitting, sleeping, usage of electrical appliances and plumbing components. The prototype is built upon inexpensive, off-the-shelf hardware (e.g., various sensors, Arduino microcontrollers, ZigBee-compatible wireless communication modules) and license-free software, thereby ensuring low system deployment costs. The network comprises nodes placed in a house's main rooms or mounted on furniture, one wearable node, one actuator node and a centralized processing element (coordinator). Upon detecting significant deviations from the ordinary activity patterns of individuals and/or sudden falls, the system issues automated alarms which may be forwarded to authorized caregivers via a variety of communication channels. Furthermore, measured environmental parameters and activity incidents may be monitored through standard web interfaces.

  20. Hands-On Experiences in Deploying Cost-Effective Ambient-Assisted Living Systems

    Directory of Open Access Journals (Sweden)

    Athanasios Dasios

    2015-06-01

    Full Text Available Older adults’ preferences to remain independent in their own homes along with the high costs of nursing home care have motivated the development of Ambient Assisted Living (AAL technologies which aim at improving the safety, health conditions and wellness of the elderly. This paper reports hands-on experiences in designing, implementing and operating UbiCare, an AAL based prototype system for elderly home care monitoring. The monitoring is based on the recording of environmental parameters like temperature and light intensity as well as micro-level incidents which allows one to infer daily activities like moving, sitting, sleeping, usage of electrical appliances and plumbing components. The prototype is built upon inexpensive, off-the-shelf hardware (e.g., various sensors, Arduino microcontrollers, ZigBee-compatible wireless communication modules and license-free software, thereby ensuring low system deployment costs. The network comprises nodes placed in a house’s main rooms or mounted on furniture, one wearable node, one actuator node and a centralized processing element (coordinator. Upon detecting significant deviations from the ordinary activity patterns of individuals and/or sudden falls, the system issues automated alarms which may be forwarded to authorized caregivers via a variety of communication channels. Furthermore, measured environmental parameters and activity incidents may be monitored through standard web interfaces.

  1. Lived Experiences of Educational Leaders in Iranian Medical Education System: A Qualitative Study.

    Science.gov (United States)

    Sohrabi, Zohreh; Kheirkhah, Masoomeh; Vanaki, Zohreh; Arabshahi, Kamran Soltani; Farshad, Mohammad Mahdi; Farshad, Fatemeh; Farahani, Mansoureh Ashgale

    2015-12-18

    High quality educational systems are necessary for sustainable development and responding to the needs of society. In the recent decades, concerns have increased on the quality of education and competency of graduates. Since graduates of medical education are directly involved with the health of society, the quality of this system is of high importance. Investigation in the lived experience of educational leaders in the medical education systems can help to promote its quality. The present research examines this issue in Iran. The study was done using content-analysis qualitative approach and semi-structured interviews. The participants included 26 authorities including university chancellors and vice-chancellors, ministry heads and deputies, deans of medical and basic sciences departments, education expert, graduates, and students of medical fields. Sampling was done using purposive snowball method. Data were analyzed using conventional content analysis. Five main categories and 14 sub-categories were extracted from data analysis including: quantity-orientation, ambiguity in the trainings, unsuitable educational environment, personalization of the educational management, and ineffective interpersonal relationship. The final theme was identified as "Education in shadow". Personalization and inclusion of personal preferences in management styles, lack of suitable grounds, ambiguity in the structure and process of education has pushed medical education toward shadows and it is not the first priority; this can lead to incompetency of medical science graduates.

  2. System study on partitioning and transmutation of long-lived isotopes

    International Nuclear Information System (INIS)

    Szieberth, M.

    2001-01-01

    The management of long-lived isotopes - transuranium elements and fission products - produced in nuclear reactors is a problem that substantially affects the public acceptance of nuclear energy, and may influence the long-term hazard caused by energy production. Partitioning and transmutation of spent fuel materials offer a suitable solution to this problem. After the nuclear community had realised this fact, the number of publications on this topic significantly increased but there is still a lack of studies that include the analysis of not only one instrument but also the whole nuclear energy system. However, from the viewpoint of Partitioning and transmutation's implementation a substantial question is the cooperation of plants optimised for energy generation and others for partitioning or transmutation. In order to analyse this problem, the schemes of different systems are framed and their mathematical models are worked out. The systems are evaluated through the long-term risks caused by the waste deposited in final disposal, and the risks are described by a newly defined quantity, the residual hazard index. (author)

  3. The Biosphere as a Living System. On Peculiarities of the Evolutionary Process on the Biosphere Level

    Directory of Open Access Journals (Sweden)

    Alexej Yablokov

    2016-10-01

    ; spontaneity and non-directional changes of the development programs; securing successful changes by natural selection; geometrical progression of reproduction as a “spring” of life. There are four basic levels of organization of life: molecular-genetics, ontogenetics, species-populational, ecosystemic. Among the main features of the evolution of the biosphere: spreading of life on the planet; the uprising of the biosphere’ turnover of matters on the basis of the use of solar energy; increasing of the closeness of this turnover; strengthening the energy flow through the biosphere; the increase in mass of organic matter involved in this cycle; the emergence of the genetic code; the emergence of eukaryotes; increasing of the structural and functional diversity of the biosphere. Among the major achievements of evolution in the plant world: improving the chemical mechanisms of photosynthesis, plants access to land (the appearance of vascular and root systems; the growth of the photosynthetic capacity of terrestrial plant communities. Among the main achievements of evolution in the animal world: the appearance of the skeleton, hemoglobin; increasing the independence from the external factors (growth of a homeostasis; the emergence of the nervous system and sociality. Among the patterns of evolution of organs and functions in different groups of living organisms: the intensification of functions; intensification of the multifunctionality and duplications of biological systems components; supplementation (rather than substitution of new functions to the old. Chorologically (spatially biosphere is composed of ecosystems of all sizes, including biogeocoenoses (which are the ecosystems within the boundaries of the phytocenosis. Biogeocoenoses are minimal spatial unit of biosphere with its own evolutionary destiny (but not "one more" name of an ecosystem, is as usual treated in the western literature. The Biosphere as whole is not only the largest Earth’ ecosystem, but also

  4. Pre–Service Teachers’ Lived Experiences with Taking Courses through Learning Management Systems: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Esra ERGUL SONMEZ

    2018-04-01

    Full Text Available Learning management systems (LMS are web–based platforms used for enhancing and supporting classroom teaching or delivering online instruction. Much of the earlier research has focused on their technological features and implementations into instruction. However, investigating what and how teachers and students think about and experience with LMS based on their actual usage is needed to realize educational potential of these systems. This study aimed to investigate pre–service teachers’ lived experiences about taking courses through Moodle LMS. The research was designed as a qualitative study. Data were collected through semi–structured interviews and analyzed through content analysis technique via Nvivo 7.0 software. The sample included 25 college students majoring in Computer and Instructional Technology Education at a state university in Turkey. Majority of the participants indicated that Moodle was user–friendly, beneficial and enhancer for interaction with both instructor and course content. Participants identified “assignments”, “resources”, and “forum” as the most effective instructional modules. On the other hand, some argued that Moodle could not provide face–to–face interaction like in the classrooms and thus it was not suitable for certain math and non–math courses requiring such interaction. They also found registration to course website as the biggest technical challenge.

  5. Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems.

    Science.gov (United States)

    Bashor, Caleb J; Horwitz, Andrew A; Peisajovich, Sergio G; Lim, Wendell A

    2010-01-01

    The living cell is an incredibly complex entity, and the goal of predictively and quantitatively understanding its function is one of the next great challenges in biology. Much of what we know about the cell concerns its constituent parts, but to a great extent we have yet to decode how these parts are organized to yield complex physiological function. Classically, we have learned about the organization of cellular networks by disrupting them through genetic or chemical means. The emerging discipline of synthetic biology offers an additional, powerful approach to study systems. By rearranging the parts that comprise existing networks, we can gain valuable insight into the hierarchical logic of the networks and identify the modular building blocks that evolution uses to generate innovative function. In addition, by building minimal toy networks, one can systematically explore the relationship between network structure and function. Here, we outline recent work that uses synthetic biology approaches to investigate the organization and function of cellular networks, and describe a vision for a synthetic biology toolkit that could be used to interrogate the design principles of diverse systems.

  6. A daily living activity remote monitoring system for solitary elderly people.

    Science.gov (United States)

    Maki, Hiromichi; Ogawa, Hidekuni; Matsuoka, Shingo; Yonezawa, Yoshiharu; Caldwell, W Morton

    2011-01-01

    A daily living activity remote monitoring system has been developed for supporting solitary elderly people. The monitoring system consists of a tri-axis accelerometer, six low-power active filters, a low-power 8-bit microcontroller (MC), a 1GB SD memory card (SDMC) and a 2.4 GHz low transmitting power mobile phone (PHS). The tri-axis accelerometer attached to the subject's chest can simultaneously measure dynamic and static acceleration forces produced by heart sound, respiration, posture and behavior. The heart rate, respiration rate, activity, posture and behavior are detected from the dynamic and static acceleration forces. These data are stored in the SD. The MC sends the data to the server computer every hour. The server computer stores the data and makes a graphic chart from the data. When the caregiver calls from his/her mobile phone to the server computer, the server computer sends the graphical chart via the PHS. The caregiver's mobile phone displays the chart to the monitor graphically.

  7. High rate gamma spectroscopy system for activation analysis of short-lived isomeric transitions

    Energy Technology Data Exchange (ETDEWEB)

    Westphall, G P [Atominstitut der Oesterreichischen Hochschulen, Vienna

    1976-07-15

    A high rate spectroscopy system specially suited for measurement of short-lived isomeric transitions is described, which, as part of a fast activation analysis facility at the TRIGA Mark II reactor, provides for automatic recording and immediate evaluation of gamma spectra taken from nuclides activated at stationary or pulsed reactor power. The system consists of a commercial de-coupled Ge(Li)-detector of 70 cm/sup 3/ modified for recycling operation for input rates in excess of 500000 c/s /sup 60/Co, a time variant trapezoidal shaping section and a fast constant dead-time ADC coupled to a programmed multichannel analyzer. Novel circuits for efficient pile-up rejection and time variant base line restoration extend the concept of gated integration up to count rates of more than 200000 c/s /sup 60/Co. Time-sequenced recording of spectra is performed by a minicomputer operated as a front-end processor of a larger laboratory computer, where final data processing takes place. New concepts for very simple and cost-effective implementation of multichannel analyzers by means of general purpose small computers are described.

  8. Biologically inspired information theory: Adaptation through construction of external reality models by living systems.

    Science.gov (United States)

    Nakajima, Toshiyuki

    2015-12-01

    Higher animals act in the world using their external reality models to cope with the uncertain environment. Organisms that have not developed such information-processing organs may also have external reality models built in the form of their biochemical, physiological, and behavioral structures, acquired by natural selection through successful models constructed internally. Organisms subject to illusions would fail to survive in the material universe. How can organisms, or living systems in general, determine the external reality from within? This paper starts with a phenomenological model, in which the self constitutes a reality model developed through the mental processing of phenomena. Then, the it-from-bit concept is formalized using a simple mathematical model. For this formalization, my previous work on an algorithmic process is employed to constitute symbols referring to the external reality, called the inverse causality, with additional improvements to the previous work. Finally, as an extension of this model, the cognizers system model is employed to describe the self as one of many material entities in a world, each of which acts as a subject by responding to the surrounding entities. This model is used to propose a conceptual framework of information theory that can deal with both the qualitative (semantic) and quantitative aspects of the information involved in biological processes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Ecology and social system of northern gibbons living in cold seasonal forests.

    Science.gov (United States)

    Guan, Zhen-Hua; Ma, Chang-Yong; Fei, Han-Lan; Huang, Bei; Ning, Wen-He; Ni, Qing-Yong; Jiang, Xue-Long; Fan, Peng-Fei

    2018-07-18

    Gibbons in China represent the northernmost margin of present day gibbon species distribution (around N25°). Compared to tropical habitats, northern gibbon habitats are characterized by low temperatures and remarkable seasonal variation in fruit abundance. How gibbons adapt to their cold and seasonal habitats and what ecological factors affect their sociality are key questions for understanding their ecology and social system evolution, the elucidation of which will contribute to the conservation of these special populations/species. According to preliminary short-term studies, northern gibbons consume more leaves and use larger home ranges than tropical gibbons. Interestingly, some Nomascus groups consist of more than one adult female. However, these preliminary results are not well understood or incorporated into current socio-ecological theories regarding gibbon species. To better understand northern gibbons, our team has systematically studied three habituated groups of Nomascus concolor, three groups of N. nasutus, and two habituated groups of Hoolock tianxing since 2002. In this paper, we stress the challenges facing gibbons living in northern habitats and summarize their behavioral adaptations to their harsh environments. We also describe the northern gibbon social system and discuss the potential relationships between their ecology and sociality. Finally, we highlight future research questions related to northern gibbons in China.

  10. The place of assisted living in long-term care and related service systems.

    Science.gov (United States)

    Stone, Robyn I; Reinhard, Susan C

    2007-01-01

    The purpose of this article is to describe how assisted living (AL) fits with other long-term-care services. We analyzed the evolution of AL, including the populations served, the services offered, and federal and state policies that create various incentives or disincentives for using AL to replace other forms of care such as nursing home care or home care. Provider models that have emerged include independent senior housing with services, freestanding AL, nursing home expansion, and continuing care retirement communities. Some integrated health systems have also built AL into their array of services. Federal and state policy rules for financing and programs also shape AL, and states vary in how deliberately they try to create an array of options with specific roles for AL. Among state policies reviewed are reimbursement and rate-setting policies, admission and discharge criteria, and nurse practice policies that permit or prohibit various nursing tasks to be delegated in AL settings. Recent initiatives to increase flexible home care, such as nursing home transition programs, cash and counseling, and money-follows-the-person initiatives may influence the way AL emerges in a particular state. There is no single easy answer about the role of AL. To understand the current role and decide how to shape the future of AL, researchers need information systems that track the transitions individuals make during their long-term-care experiences along with information about the case-mix characteristics and service needs of the clientele.

  11. A high rate gamma spectroscopy system for activation analysis of short lived isomeric transitions

    Energy Technology Data Exchange (ETDEWEB)

    Westphal, G P [Atominstitut, Vienna (Austria)

    1976-07-01

    A high rate spectroscopy system specially suited for measurement of short-lived isomeric transitions is described, which, as part of a fast activation analysis facility at the TRIGA Mark II reactor, provides for automatic recording and immediate evaluation of gamma spectra taken from nuclides activated at stationary or pulsed reactor power. The system consists of a commercial DC-coupled Ge(Li)-detector of 70 cm{sup 3} modified for recycling operation for input rates in excess of 500,000 c/s Co-60, a time variant trapezoidal shaping section and a fast constant dead-time ADC coupled to a programmed multi-channel analyzer. Novel circuits for efficient pile-up rejection and time variant base line restoration extend the concept of gated integration up to count rates of more than 300,000 c/s Co-60. Time-sequenced recording of spectra is performed by a mini computer operated as a front-end processor of a larger laboratory computer, where final data processing takes place. New concepts for very simple and cost-effective implementation of multi-channel analyzers by means of general purpose small computers are described. (author)

  12. Ecology and social system of northern gibbons living in cold seasonal forests

    Directory of Open Access Journals (Sweden)

    Zhen-Hua Guan

    2018-07-01

    Full Text Available Gibbons in China represent the northernmost margin of present day gibbon species distribution (around N25°. Compared to tropical habitats, northern gibbon habitats are characterized by low temperatures and remarkable seasonal variation in fruit abundance. How gibbons adapt to their cold and seasonal habitats and what ecological factors affect their sociality are key questions for understanding their ecology and social system evolution, the elucidation of which will contribute to the conservation of these special populations/species. According to preliminary short-term studies, northern gibbons consume more leaves and use larger home ranges than tropical gibbons. Interestingly, some Nomascus groups consist of more than one adult female. However, these preliminary results are not well understood or incorporated into current socio-ecological theories regarding gibbon species. To better understand northern gibbons, our team has systematically studied three habituated groups of Nomascus concolor, three groups of N. nasutus, and two habituated groups of Hoolock tianxing since 2002. In this paper, we stress the challenges facing gibbons living in northern habitats and summarize their behavioral adaptations to their harsh environments. We also describe the northern gibbon social system and discuss the potential relationships between their ecology and sociality. Finally, we highlight future research questions related to northern gibbons in China.

  13. ATLAS Live: Collaborative Information Streams

    Energy Technology Data Exchange (ETDEWEB)

    Goldfarb, Steven [Department of Physics, University of Michigan, Ann Arbor, MI 48109 (United States); Collaboration: ATLAS Collaboration

    2011-12-23

    I report on a pilot project launched in 2010 focusing on facilitating communication and information exchange within the ATLAS Collaboration, through the combination of digital signage software and webcasting. The project, called ATLAS Live, implements video streams of information, ranging from detailed detector and data status to educational and outreach material. The content, including text, images, video and audio, is collected, visualised and scheduled using digital signage software. The system is robust and flexible, utilizing scripts to input data from remote sources, such as the CERN Document Server, Indico, or any available URL, and to integrate these sources into professional-quality streams, including text scrolling, transition effects, inter and intra-screen divisibility. Information is published via the encoding and webcasting of standard video streams, viewable on all common platforms, using a web browser or other common video tool. Authorisation is enforced at the level of the streaming and at the web portals, using the CERN SSO system.

  14. ATLAS Live: Collaborative Information Streams

    International Nuclear Information System (INIS)

    Goldfarb, Steven

    2011-01-01

    I report on a pilot project launched in 2010 focusing on facilitating communication and information exchange within the ATLAS Collaboration, through the combination of digital signage software and webcasting. The project, called ATLAS Live, implements video streams of information, ranging from detailed detector and data status to educational and outreach material. The content, including text, images, video and audio, is collected, visualised and scheduled using digital signage software. The system is robust and flexible, utilizing scripts to input data from remote sources, such as the CERN Document Server, Indico, or any available URL, and to integrate these sources into professional-quality streams, including text scrolling, transition effects, inter and intra-screen divisibility. Information is published via the encoding and webcasting of standard video streams, viewable on all common platforms, using a web browser or other common video tool. Authorisation is enforced at the level of the streaming and at the web portals, using the CERN SSO system.

  15. ATLAS Live: Collaborative Information Streams

    CERN Document Server

    Goldfarb, S; The ATLAS collaboration

    2010-01-01

    I report on a pilot project launched in 2010 focusing on facilitating communication and information exchange within the ATLAS Collaboration, through the combination of digital signage software and webcasting. The project, called ATLAS Live, implements video streams of information, ranging from detailed detector and data status to educational and outreach material. The content, including text, images, video and audio, is collected, visualised and scheduled using the SCALA digital signage software system. The system is robust and flexible, allowing for the usage of scripts to input data from remote sources, such as the CERN Document Server, Indico, or any available URL, and to integrate these sources into professional-quality streams, including text scrolling, transition effects, inter and intrascreen divisibility. The video is made available to the collaboration or public through the encoding and webcasting of standard video streams, viewable on all common platforms, using a web browser or other common video t...

  16. Some Physical Principles Governing Spatial and Temporal Organization in Living Systems

    Science.gov (United States)

    Ali, Md Zulfikar

    Spatial and temporal organization in living organisms are crucial for a variety of biological functions and arise from the interplay of large number of interacting molecules. One of the central questions in systems biology is to understand how such an intricate organization emerges from the molecular biochemistry of the cell. In this dissertation we explore two projects. The first project relates to pattern formation in a cell membrane as an example of spatial organization, and the second project relates to the evolution of oscillatory networks as a simple example of temporal organization. For the first project, we introduce a model for pattern formation in a two-component lipid bilayer and study the interplay between membrane composition and membrane geometry, demonstrating the existence of a rich phase diagram. Pattern formation is governed by the interplay between phase separation driven by lipid-lipid interactions and tendency of lipid domains with high intrinsic curvature to deform the membrane away from its preferred position. Depending on membrane parameters, we find the formation of compact lipid micro-clusters or of striped domains. We calculate the stripe width analytically and find good agreement with stripe widths obtained from the simulations. For the second project, we introduce a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm and apply it to study the following problems. Using the model, we study robustness and designabilty of a 2-component network that generate oscillations. We completely enumerate the sequence space and the phenotypic space, and discuss the relationship between designabilty, robustness and evolvability. We further apply the model to studies of neutral drift in networks that yield oscillatory dynamics, e.g. starting with a relatively simple network and allowing it to evolve by adding nodes and connections while requiring that oscillatory dynamics be preserved

  17. Living in the cold

    DEFF Research Database (Denmark)

    Schostag, Morten Dencker

    Permafrost affected soil systems represent 17% of the global land area. It has been shown that these soil systems contain a large amount of organic carbon that have the risk to be released as greenhouse gasses to the atmosphere by microbial processes. The active layer of soil overlaying permafros...

  18. "Wetlands: Water Living Filters?",

    OpenAIRE

    Dordio, Ana; Palace, A. J.; Pinto, Ana Paula

    2008-01-01

    Human societies have indirectly used natural wetlands as wastewater discharge sites for many centuries. Observations of the wastewater depuration capacity of natural wetlands have led to a greater understanding of the potential of these ecosystems for pollutant assimilation and have stimulated the development of artificial wetlands systems for treatment of wastewaters from a variety of sources. Constructed wetlands, in contrast to natural wetlands, are human-made systems that are designed, bu...

  19. Women's lived experiences of learning to live with osteoporosis

    DEFF Research Database (Denmark)

    Hansen, Carrinna A; Abrahamsen, Bo; Konradsen, Hanne

    2017-01-01

    qualitative interviews were conducted with fifteen recently diagnosed Danish women. A longitudinal design was chosen since this allows an investigation of the perspective over time. The interviews were conducted in the period of March 2011 to August 2012. Data were analyzed using a phenomenological......BACKGROUND: A vast amount of literature exists concerning pharmaceutical adherence in osteoporosis. However, the process of learning to live with osteoporosis over time remains largely unknown. The purpose of this study was to gain a deeper understanding of the continued process of how women learn...... to live with osteoporosis. Our objective was to explore what characterizes women's experiences of living with osteoporosis during the first year after diagnosis, when patients are prescribed anti-osteoporotic treatment, without having experienced an osteoporotic fracture. METHODS: Forty-two narrative...

  20. The Living Challenges of Ambient Assisted Living - A Literature Review

    DEFF Research Database (Denmark)

    Bygholm, Ann; Kanstrup, Anne Marie

    2015-01-01

    Ambient Assisted Living (AAL) is a rapidly evolving research and development area propelled by scarcity of health resources caused by an aging workforce and increase of Citizens in need of health care and health assistance on a regular basis. This paper presents a literature review of the current...... state-of-the-art of AAL. The objective is to point towards methodological actions to be taken into account in AAL research on this basis. Searches were conducted in five research databases. The search identified 86 papers. 10 of these papers were review papers chosen for analysis. The analysis presents...... an overview of the current status of AAL within the following categories: technology, users, application domains, rationales, successes and challenges of AAL. The paper concludes that the living part, i.e. the everyday practice of people living with Assistive Technology, is the primary challenge to the field...

  1. Living with Layoffs.

    Science.gov (United States)

    Hartzell, Gary N.

    1992-01-01

    Afterschool systems reduce the number of employees, the surviving staff members often experience low morale, distrust, and guilt. Administrators can help the survivors by answering questions about the layoff: whether it was necessary; whether it was conducted fairly; whether those who were laid off were treated humanely; and what is the status of…

  2. Designing for Quieter Living

    Indian Academy of Sciences (India)

    IAS Admin

    A loud speaker or a public address system or any sound producing instrument or a musical instrument or a .... well-known example is the construction of aircraft win- dows. 10. Design of ... for landscaping as well as environmental noise control.

  3. Senior living technology.

    Science.gov (United States)

    Weiss, G

    1999-10-01

    The pros and cons of long term care's shift to a prospective payment system will be debated well into the next millennium, but its effects have already been profound. Not least has been the role PPS has played in dragging providers into the information age. Providers who were once steadfast in their refusal to participate in the computer revolution are now eager converts, implementing innovative information and clinical technologies to operate more efficiently and improve quality of care. Major changes rarely happen overnight. The long process of upgrading information systems and integrating new clinical technologies will remain arduous for years to come. But innovative technologies (including non-computerized devices and equipment ranging from lift systems to weightlifting equipment) will play an ever-increasing role as the industry takes a more consumer-driven approach to delivery of care. While some providers complain that vendors have been slow to develop the level of sophisticated, integrative systems they require, vendors fault providers for not being able or willing to invest the capital necessary to upgrade their platforms to support state-of-the-art software. But partnering rather than finger-pointing appears to be winning the day as facilities and vendors intensify their efforts to create more and better technology for long term care. In the following pages, we look at a number of innovative providers--from Bronx, New York, to Oshkosh, Wisconsin, from big chains to mom-and-pops--who have come up with creative solutions to common problems.

  4. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

    Directory of Open Access Journals (Sweden)

    Malene Brohus

    Full Text Available Naked mole-rats (Heterocephalus glaber (NMRs are the longest living rodents known. They show negligible senescence, and are resistant to cancers and certain damaging effects associated with aging. The insulin-like growth factors (IGFs have pluripotent actions, influencing growth processes in virtually every system of the body. They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. The IGFs are likewise involved in progression of cancers by mediating survival signals in malignant cells. This report presents a full characterization of the IGF system in the NMR: ligands, receptors, IGF binding proteins (IGFBPs, and IGFBP proteases. A particular emphasis was placed on the IGFBP protease, pregnancy-associated plasma protein-A (PAPP-A, shown to be an important lifespan modulator in mice. Comparisons of IGF-related genes in the NMR with human and murine sequences indicated no major differences in essential parts of the IGF system, including PAPP-A. The protease was shown to possess an intact active site despite the report of a contradictory genome sequence. Furthermore, PAPP-A was expressed and translated in NMRs cells and retained IGF-dependent proteolytic activity towards IGFBP-4 and IGF-independent activity towards IGFBP-5. However, experimental data suggest differential regulatory mechanisms for PAPP-A expression in NMRs than those described in humans and mice. This overall description of the IGF system in the NMR represents an initial step towards elucidating the complex molecular mechanisms underlying longevity, and how these animals have evolved to ensure a delayed and healthy aging process.

  5. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

    Science.gov (United States)

    Brohus, Malene; Gorbunova, Vera; Faulkes, Chris G; Overgaard, Michael T; Conover, Cheryl A

    2015-01-01

    Naked mole-rats (Heterocephalus glaber) (NMRs) are the longest living rodents known. They show negligible senescence, and are resistant to cancers and certain damaging effects associated with aging. The insulin-like growth factors (IGFs) have pluripotent actions, influencing growth processes in virtually every system of the body. They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. The IGFs are likewise involved in progression of cancers by mediating survival signals in malignant cells. This report presents a full characterization of the IGF system in the NMR: ligands, receptors, IGF binding proteins (IGFBPs), and IGFBP proteases. A particular emphasis was placed on the IGFBP protease, pregnancy-associated plasma protein-A (PAPP-A), shown to be an important lifespan modulator in mice. Comparisons of IGF-related genes in the NMR with human and murine sequences indicated no major differences in essential parts of the IGF system, including PAPP-A. The protease was shown to possess an intact active site despite the report of a contradictory genome sequence. Furthermore, PAPP-A was expressed and translated in NMRs cells and retained IGF-dependent proteolytic activity towards IGFBP-4 and IGF-independent activity towards IGFBP-5. However, experimental data suggest differential regulatory mechanisms for PAPP-A expression in NMRs than those described in humans and mice. This overall description of the IGF system in the NMR represents an initial step towards elucidating the complex molecular mechanisms underlying longevity, and how these animals have evolved to ensure a delayed and healthy aging process.

  6. Molecular machines in living cells. Seibutsu no bunshi kikai to sono system

    Energy Technology Data Exchange (ETDEWEB)

    Osawa, F. (Aichi Inst. of Tech., Nagoya (Japan))

    1992-12-20

    At first, flagellar motors of bacteria are reviewed as a typical example of molecular machines in living cells. A rotational motor is embedded in the cell membrane at the root of the flagellum. The driving power of the rotation is the flow of hydrogen ion from the inside to the outside of the cell. In a normal state of a bacterium, potential difference of about 0.2 V is produced by the ion pump existing in the cell membrane. A molecular motor of sliding motion of muscle attracts the attention on the relation of the input and output of the molecular motor. The mechanism of the smooth motion without fluctuation in the fluctuated environment and the fluctuated input is unknown. Next, the motion of Paramecium is discussed as an example of a system composed of a number of molecular machines. Paramecium moves to a place of a suitable temperature when placed in a water tank with temperature gradient, however, it does not stop the motion at the place of the suitable temperature and increases a probability to change the direction when leaving, that is it takes a method of indirect probabilistic control. 12 refs., 8 figs.

  7. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery.

    Science.gov (United States)

    Tiefenbach, Jens; Moll, Pamela R; Nelson, Meryl R; Hu, Chun; Baev, Lilia; Kislinger, Thomas; Krause, Henry M

    2010-03-22

    Nuclear receptors (NRs) belong to a superfamily of transcription factors that regulate numerous homeostatic, metabolic and reproductive processes. Taken together with their modulation by small lipophilic molecules, they also represent an important and successful class of drug targets. Although many NRs have been targeted successfully, the majority have not, and one third are still orphans. Here we report the development of an in vivo GFP-based reporter system suitable for monitoring NR activities in all cells and tissues using live zebrafish (Danio rerio). The human NR fusion proteins used also contain a new affinity tag cassette allowing the purification of receptors with bound molecules from responsive tissues. We show that these constructs 1) respond as expected to endogenous zebrafish hormones and cofactors, 2) facilitate efficient receptor and cofactor purification, 3) respond robustly to NR hormones and drugs and 4) yield readily quantifiable signals. Transgenic lines representing the majority of human NRs have been established and are available for the investigation of tissue- and isoform-specific ligands and cofactors.

  8. A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery.

    Directory of Open Access Journals (Sweden)

    Jens Tiefenbach

    2010-03-01

    Full Text Available Nuclear receptors (NRs belong to a superfamily of transcription factors that regulate numerous homeostatic, metabolic and reproductive processes. Taken together with their modulation by small lipophilic molecules, they also represent an important and successful class of drug targets. Although many NRs have been targeted successfully, the majority have not, and one third are still orphans. Here we report the development of an in vivo GFP-based reporter system suitable for monitoring NR activities in all cells and tissues using live zebrafish (Danio rerio. The human NR fusion proteins used also contain a new affinity tag cassette allowing the purification of receptors with bound molecules from responsive tissues. We show that these constructs 1 respond as expected to endogenous zebrafish hormones and cofactors, 2 facilitate efficient receptor and cofactor purification, 3 respond robustly to NR hormones and drugs and 4 yield readily quantifiable signals. Transgenic lines representing the majority of human NRs have been established and are available for the investigation of tissue- and isoform-specific ligands and cofactors.

  9. Long-lived trimers in a quasi-two-dimensional Fermi system

    Science.gov (United States)

    Laird, Emma K.; Kirk, Thomas; Parish, Meera M.; Levinsen, Jesper

    2018-04-01

    We consider the problem of three distinguishable fermions confined to a quasi-two-dimensional (quasi-2D) geometry, where there is a strong harmonic potential in one direction. We go beyond previous theoretical work and investigate the three-body bound states (trimers) for the case where the two-body short-range interactions between fermions are unequal. Using the scattering parameters from experiments on ultracold 6Li atoms, we calculate the trimer spectrum throughout the crossover from two to three dimensions. We find that the deepest Efimov trimer in the 6Li system is unaffected by realistic quasi-2D confinements, while the first excited trimer smoothly evolves from a three-dimensional-like Efimov trimer to an extended 2D-like trimer as the attractive interactions are decreased. We furthermore compute the excited trimer wave function and quantify the stability of the trimer against decay into a dimer and an atom by determining the probability that three fermions approach each other at short distances. Our results indicate that the lifetime of the trimer can be enhanced by at least an order of magnitude in the quasi-2D geometry, thus opening the door to realizing long-lived trimers in three-component Fermi gases.

  10. Living with the risk

    International Nuclear Information System (INIS)

    Menke-Glueckert, P.

    1980-01-01

    The belief in technique and progress was substituted by an increasing awareness of the environment. There is a deep crisis in the confidence in technical facilities and doubts in the use of technological perefectionism. The optimistic attitude towards technique turned into criticism against technique. The extensive fear of the future includes also a debate on the real safety of technical equipment, systems and processes. There are constantly growing doubts in the conventional safety concepts being still sufficient and in the safety requirements being an integrated point of each technological problem. (orig./HP) [de

  11. Dynamical Detection of Topological Phase Transitions in Short-Lived Atomic Systems

    OpenAIRE

    Setiawan, F.; Sengupta, K.; Spielman, I. B.; Sau, Jay D.

    2015-01-01

    We demonstrate that dynamical probes provide direct means of detecting the topological phase transition (TPT) between conventional and topological phases, which would otherwise be difficult to access because of loss or heating processes. We propose to avoid such heating by rapidly quenching in and out of the short-lived topological phase across the transition that supports gapless excitations. Following the quench, the distribution of excitations in the final conventional phase carries signat...

  12. ATLAS Live: Collaborative Information Streams

    CERN Document Server

    Goldfarb, S; The ATLAS collaboration

    2011-01-01

    I report on a pilot project launched in 2010 focusing on facilitating communication and information exchange within the ATLAS Collaboration, through the combination of digital signage software and webcasting. The project, called ATLAS Live, implements video streams of information, ranging from detailed detector and data status to educational and outreach material. The content, including text, images, video and audio, is collected, visualised and scheduled using digital signage software. The system is robust and flexible, utilizing scripts to input data from remote sources, such as the CERN Document Server, Indico, or any available URL, and to integrate these sources into professional-quality streams, including text scrolling, transition effects, inter and intra-screen divisibility. Information is published via the encoding and webcasting of standard video streams, viewable on all common platforms, using a web browser or other common video tool. Authorisation is enforced at the level of the streaming and at th...

  13. Living electrode as a long-lived photoconverter for biophotolysis of water

    Energy Technology Data Exchange (ETDEWEB)

    Ochiai, H.; Shibata, H.; Sawa, Y.; Katoh, T.

    1980-05-01

    Living blue-green algae (Mastigocladus laminosus), immobilized on an SnO/sub 2/ optically transparent electrode with calcium alginate, functioned as an anodic photo electrode on continuous illumination for periods of time adequate for use in a conventional electrochemical cell. This living electrode shows promise of use as a long-lived photoconverter of solar radiant energy to electric energy and as a suitable replacement for unstable chloroplast systems.

  14. A Quality Improvement System to Manage Feeding Assistance Care in Assisted-Living.

    Science.gov (United States)

    Simmons, Sandra F; Coelho, Chris S; Sandler, Andrew; Schnelle, John F

    2018-03-01

    To describe a feasible quality improvement system to manage feeding assistance care processes in an assisted living facility (ALF) that provides dementia care and the use of these data to maintain the quality of daily care provision and prevent unintentional weight loss. Supervisory ALF staff used a standardized observational protocol to assess feeding assistance care quality during and between meals for 12 consecutive months for 53 residents receiving dementia care. Direct care staff received feedback about the quality of assistance and consistency of between-meal snack delivery for residents with low meal intake and/or weight loss. On average, 78.4% of the ALF residents consumed more than one-half of each served meal and/or received staff assistance during meals to promote consumption over the 12 months. An average of 79.7% of the residents were offered snacks between meals twice per day. The prevalence of unintentional weight loss averaged 1.3% across 12 months. A quality improvement system resulted in sustained levels of mealtime feeding assistance and between-meal snack delivery and a low prevalence of weight loss among ALF residents receiving dementia care. Given that many ALF residents receiving dementia care are likely to be at risk for low oral intake and unintentional weight loss, ALFs should implement a quality improvement system similar to that described in this project, despite the absence of regulations to do so. Copyright © 2018 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

  15. Preliminary Evaluation of a Personal Healthcare System Prototype for Cognitive eRehabilitation in a Living Assistance Domain

    Directory of Open Access Journals (Sweden)

    Matteo Pastorino

    2014-06-01

    Full Text Available The integration of rehabilitation systems in an ambient assisted living environment can provide a powerful and versatile tool for long-term stroke rehabilitation goals. This paper introduces a novel concept of a personalized cognitive rehabilitation system in a naturalistic setting. The proposed platform was developed within the CogWatch project, with the intent of fostering independence in activities of daily living in patients with apraxia and action disorganization syndrome. Technical usability was evaluated in a series of pilot experiments, which illustrate how this approach may help to retrain patients in activities of daily living. The first system prototype has been tested with 36 participants divided into three groups, providing an exploratory evaluation of the usability of this solution and its acceptability. The technical solutions used within the CogWatch project are targeted to meet both the end users’ needs from the interaction and usability point of views and the clinical requirements associated with the use of such systems. The challenges behind the development of ambient assisted living systems for cognitive rehabilitation are discussed.

  16. Live Piloting and Prototyping

    Directory of Open Access Journals (Sweden)

    Francesca Rizzo

    2013-07-01

    Full Text Available This paper presents current trends in service design research concerning large scale projects aimed at generating changes at a local scale. The strategy adopted to achieve this, is to co-design solutions including future users in the development process, prototyping and testing system of products and services before their actual implementation. On the basis of experience achieved in the European Project Life 2.0, this paper discusses which methods and competencies are applied in the development of these projects, eliciting the lessons learnt especially from the piloting phase in which the participatory design (PD approach plays a major role. In the first part, the topic is introduced jointly with the theoretical background where the user center design and participatory design methods are presented; then the Life 2.0 project development is described; finally the experience is discussed from a service design perspective, eliciting guidelines for piloting and prototyping services in a real context of use. The paper concludes reflecting on the designers’ role and competencies needed in this process.

  17. Strategies for Living in Houses

    Directory of Open Access Journals (Sweden)

    Colin Ripley

    2017-12-01

    Full Text Available The problem of queer housing can never go away because it is a central component of queerness. Queer housing is a contradiction in terms: not even a queer architect can design a queer house. But where does this leave us, as queer people living in a straight hegemony? Where does it leave us as humans with bodies, craving shelter and safety and a place to live that is in accordance with our experience of self and of living in the world? In this article the author proposes eight architectural strategies for re-occupying the Levittown Cape Cod house from 1947 for queer bodies, minds and hearts. These strategies offer modes by which the key programmatic formal and material components of the Cape Cod House can be attacked, made invalid, or détourned for queer uses, to make of the Cape Cod House a site for our pain, our longing, our anger.

  18. Where Galactic Snakes Live

    Science.gov (United States)

    2006-01-01

    This infrared image from NASA's Spitzer Space Telescope shows what astronomers are referring to as a 'snake' (upper left) and its surrounding stormy environment. The sinuous object is actually the core of a thick, sooty cloud large enough to swallow dozens of solar systems. In fact, astronomers say the 'snake's belly' may be harboring beastly stars in the process of forming. The galactic creepy crawler to the right of the snake is another thick cloud core, in which additional burgeoning massive stars might be lurking. The colorful regions below the two cloud cores are less dense cloud material, in which dust has been heated by starlight and glows with infrared light. Yellow and orange dots throughout the image are monstrous developing stars; the red star on the 'belly' of the snake is 20 to 50 times as massive as our sun. The blue dots are foreground stars. The red ball at the bottom left is a 'supernova remnant,' the remains of massive star that died in a fiery blast. Astronomers speculate that radiation and winds from the star before it died, in addition to a shock wave created when it exploded, might have played a role in creating the snake. Spitzer was able to spot the two black cloud cores using its heat-seeking infrared vision. The objects are hiding in the dusty plane of our Milky Way galaxy, invisible to optical telescopes. Because their heat, or infrared light, can sneak through the dust, they first showed up in infrared images from past missions. The cloud cores are so thick with dust that if you were to somehow transport yourself into the middle of them, you would see nothing but black, not even a star in the sky. Now, that's spooky! Spitzer's new view of the region provides the best look yet at the massive embryonic stars hiding inside the snake. Astronomers say these observations will ultimately help them better understand how massive stars form. By studying the clustering and range of masses of the stellar embryos, they hope to determine if the stars

  19. Mother-Child Interaction and Prosocial Development in Toddlers: A Multivariate Study Using the Living Systems Framework.

    Science.gov (United States)

    Bergin, Christi A. C.

    The Living Systems Framework was used to generate four categories of parent behaviors that might affect processes responsible for eliciting prosocial behavior in children: (1) teaching values, rules, and standards; (2) providing opportunities for rehearsal and mastery; (3) providing opportunities for self-regulation and self-control; and (4)…

  20. StreetTiVo: Using a P2P XML Database System to Manage Multimedia Data in Your Living Room

    NARCIS (Netherlands)

    Zhang, Ying; de Vries, A.P.; Boncz, P.; Hiemstra, Djoerd; Ordelman, Roeland J.F.; Li, Qing; Feng, Ling; Pei, Jian; Wang, Sean X.

    StreetTiVo is a project that aims at bringing research results into the living room; in particular, a mix of current results in the areas of Peer-to-Peer XML Database Management System (P2P XDBMS), advanced multimedia analysis techniques, and advanced information re- trieval techniques. The project

  1. Direct irradiation of long-lived fission products in an ATW system

    Energy Technology Data Exchange (ETDEWEB)

    Carter, T.F. [Univ. of Tennessee, Knoxville, TN (United States); Henderson, D. [Univ. of Wisconsin, Madison, WI (United States); Sailor, W.C. [Los Alamos National Laboratory, NM (United States)

    1995-10-01

    The feasibility of directly irradiating five long-lived fission products (LLFPs: {sup 79}Se, {sup 93}Zr, {sup 107}Pd, {sup 126}Sn, and {sup 135}Cs, each with a half-life greater than 10,000 years), by incorporating them into the target of an Accelerator Transmutation of Waste (ATW) system is discussed. The important parameters used to judge the feasibility of a direct irradiation system were the target`s neutron spallation yield (given in neutrons produced per incident proton), and the removal rate of the LLFP, with the baseline incineration rate set at two light water reactors (LWRs) worth of the LLFP waste per year. A target was constructed which consisted of a LLFP cylindrical {open_quotes}plug{close_quotes} inserted into the top (where the proton beam strikes) of a 30 cm radius, 100 cm length lead target. {sup 126}Sn and {sup 79}Se were each found to have high enough removal rates to support two LWR`s production of the LLFP per year of ATW operation. For the baseline plug geometry (5 cm radius, 30 cm length) containing {sup 126}Sn, 3.5 LWRs could be supported per year (at 75% beam availability). Furthermore, the addition of a {sup 126}Sn plus had a slightly positive effect on the target`s neutron yield. The neutron production was 36.83 {plus_minus}.0039 neutrons per proton with a pure lead target having a yield of 36.29 {plus_minus}.0038. It was also found that a plug composed of a tin-selenide compound (SnSe) had high enough removal rates to burn two or more reactor years of both LLFPs simultaneously.

  2. Dr. Liver: A preoperative planning system of liver graft volumetry for living donor liver transplantation.

    Science.gov (United States)

    Yang, Xiaopeng; Yang, Jae Do; Yu, Hee Chul; Choi, Younggeun; Yang, Kwangho; Lee, Tae Beom; Hwang, Hong Pil; Ahn, Sungwoo; You, Heecheon

    2018-05-01

    Manual tracing of the right and left liver lobes from computed tomography (CT) images for graft volumetry in preoperative surgery planning of living donor liver transplantation (LDLT) is common at most medical centers. This study aims to develop an automatic system with advanced image processing algorithms and user-friendly interfaces for liver graft volumetry and evaluate its accuracy and efficiency in comparison with a manual tracing method. The proposed system provides a sequential procedure consisting of (1) liver segmentation, (2) blood vessel segmentation, and (3) virtual liver resection for liver graft volumetry. Automatic segmentation algorithms using histogram analysis, hybrid level-set methods, and a customized region growing method were developed. User-friendly interfaces such as sequential and hierarchical user menus, context-sensitive on-screen hotkey menus, and real-time sound and visual feedback were implemented. Blood vessels were excluded from the liver for accurate liver graft volumetry. A large sphere-based interactive method was developed for dividing the liver into left and right lobes with a customized cutting plane. The proposed system was evaluated using 50 CT datasets in terms of graft weight estimation accuracy and task completion time through comparison to the manual tracing method. The accuracy of liver graft weight estimation was assessed by absolute difference (AD) and percentage of AD (%AD) between preoperatively estimated graft weight and intraoperatively measured graft weight. Intra- and inter-observer agreements of liver graft weight estimation were assessed by intraclass correlation coefficients (ICCs) using ten cases randomly selected. The proposed system showed significantly higher accuracy and efficiency in liver graft weight estimation (AD = 21.0 ± 18.4 g; %AD = 3.1% ± 2.8%; percentage of %AD > 10% = none; task completion time = 7.3 ± 1.4 min) than the manual tracing method (AD = 70

  3. Neutron effects on living things

    International Nuclear Information System (INIS)

    1964-01-01

    Scientific interest in neutrons and protons - two fundamental particles of the atomic nucleus - has grown in recent years as the technology of peaceful uses of atomic energy has progressed. Such interest also has increased because both protons and neutrons are encountered in outer space. However, only recently has a thorough study of the biological effects of neutrons and protons become possible, as a result of progress in making physical measurements of the radiation dose absorbed in biological systems (of plants and animals, for example). Reports of work in that field were presented in December 1962, when IAEA sponsored at Harwell Laboratory in the United Kingdom the first international symposium on detection dosimetry (measurement) and standardization of neutron radiation sources. The Harwell meeting was followed in October 1963 at Brookhaven National Laboratory, Long Island, New York, by the first scientific meeting sponsored by IAEA in the U. S. Entitled 'Biological Effects of Neutron Irradiations', the Symposium continued the review of problems of measuring radiation absorption in living things and provided in addition for several reports dealing with the effects of radiation on living organisms - plant, animal and human - and with delayed consequences of exposure to radiation, such as: change in life span; tumour incidence; and fertility. Eighteen countries were represented. Although much has been learned about X-ray and gamma-ray effects, comparatively little is known about the biological effects of neutrons, and therefore many of the Symposium papers reviewed the various aspects of neutron experimentation. Similarly, since there is increasing interest in the biological effects of protons, papers were given on that related subject.

  4. Some opinions about matter and material substances: from inanimate system -- to living according to A. Einstein general theory of relativity.

    Science.gov (United States)

    Topuria, T; Gogebashvili, N; Korsantia, B

    2005-11-01

    During transformation from inanimate to living, change of the space position of the matter causes the change of the field, as the space does not exist without the field, therefore the time-space as the properties of material substances, should undergo certain changes. The outside inanimate system, in this case a matrix, has its own time. The living system, in this case a cell, where the matter undergoes space conformation with the change of field and space-time, has its own time and it has begun to flow more rapidly than in matrix. From the surface of the body, from different energetic reservoirs oppositely charged matter substances following from special transport systems from the life system transmitted into lifeless one and change their matter space conformation, create transmission gradient that is the gradient border of time from lifeless system into live. In the case of a human, hypothetically, the gradient system of time must be of a complex scheme counting the inter-transformation and interaction gradients of outer and inner abdominal systems. Subconscious and consciousness by means of special links and messages, information selection interact and form unique connection between the systems. Subconscious serves for accelerated time system. Conscious by means of permanent contact with the environment collects and reacts in matrix time system By interconnection of these two systems ideal adaptation with the environment takes place. Time difference gradient system is an additional energy factor, by means of which respective ordered geometrical structures special for the given types are formed. The living organism is an inter-regulated interconnection global system resulting from the changes of matter and material substances space configuration.

  5. Computational optogenetics: A novel continuum framework for the photoelectrochemistry of living systems

    Science.gov (United States)

    Wong, Jonathan; Abilez, Oscar J.; Kuhl, Ellen

    2012-06-01

    Electrical stimulation is currently the gold standard treatment for heart rhythm disorders. However, electrical pacing is associated with technical limitations and unavoidable potential complications. Recent developments now enable the stimulation of mammalian cells with light using a novel technology known as optogenetics. The optical stimulation of genetically engineered cells has significantly changed our understanding of electrically excitable tissues, paving the way towards controlling heart rhythm disorders by means of photostimulation. Controlling these disorders, in turn, restores coordinated force generation to avoid sudden cardiac death. Here, we report a novel continuum framework for the photoelectrochemistry of living systems that allows us to decipher the mechanisms by which this technology regulates the electrical and mechanical function of the heart. Using a modular multiscale approach, we introduce a non-selective cation channel, channelrhodopsin-2, into a conventional cardiac muscle cell model via an additional photocurrent governed by a light-sensitive gating variable. Upon optical stimulation, this channel opens and allows sodium ions to enter the cell, inducing electrical activation. In side-by-side comparisons with conventional heart muscle cells, we show that photostimulation directly increases the sodium concentration, which indirectly decreases the potassium concentration in the cell, while all other characteristics of the cell remain virtually unchanged. We integrate our model cells into a continuum model for excitable tissue using a nonlinear parabolic second-order partial differential equation, which we discretize in time using finite differences and in space using finite elements. To illustrate the potential of this computational model, we virtually inject our photosensitive cells into different locations of a human heart, and explore its activation sequences upon photostimulation. Our computational optogenetics tool box allows us to

  6. Development of a Multisensory Wearable System for Monitoring Cigarette Smoking Behavior in Free-Living Conditions

    Directory of Open Access Journals (Sweden)

    Masudul Haider Imtiaz

    2017-11-01

    Full Text Available This paper presents the development and validation of a novel multi-sensory wearable system (Personal Automatic Cigarette Tracker v2 or PACT2.0 for monitoring of cigarette smoking in free-living conditions. The contributions of the PACT2.0 system are: (1 the implementation of a complete sensor suite for monitoring of all major behavioral manifestations of cigarette smoking (lighting events, hand-to-mouth gestures, and smoke inhalations; (2 a miniaturization of the sensor hardware to enable its applicability in naturalistic settings; and (3 an introduction of new sensor modalities that may provide additional insight into smoking behavior e.g., Global Positioning System (GPS, pedometer and Electrocardiogram(ECG or provide an easy-to-use alternative (e.g., bio-impedance respiration sensor to traditional sensors. PACT2.0 consists of three custom-built devices: an instrumented lighter, a hand module, and a chest module. The instrumented lighter is capable of recording the time and duration of all lighting events. The hand module integrates Inertial Measurement Unit (IMU and a Radio Frequency (RF transmitter to track the hand-to-mouth gestures. The module also operates as a pedometer. The chest module monitors the breathing (smoke inhalation patterns (inductive and bio-impedance respiratory sensors, cardiac activity (ECG sensor, chest movement (three-axis accelerometer, hand-to-mouth proximity (RF receiver, and captures the geo-position of the subject (GPS receiver. The accuracy of PACT2.0 sensors was evaluated in bench tests and laboratory experiments. Use of PACT2.0 for data collection in the community was validated in a 24 h study on 40 smokers. Of 943 h of recorded data, 98.6% of the data was found usable for computer analysis. The recorded information included 549 lighting events, 522/504 consumed cigarettes (from lighter data/self-registered data, respectively, 20,158/22,207 hand-to-mouth gestures (from hand IMU/proximity sensor, respectively

  7. Different positions of uncertain lives

    DEFF Research Database (Denmark)

    Stenum, Helle

    On the basis of my ethnographic research in Denmark and Spain, I will investigate and compare four different positions of illegality in two different national contexts. Legal and institutional practices on the one hand produce the conditions for migrant illegality as such, but are also decisive...... for both the lived experience as irregular migrant and the opportunities for agency and strategizing among migrants....

  8. Resensi Buku: The Living Company

    Directory of Open Access Journals (Sweden)

    Ayu Chairina Laksmi

    2009-08-01

    Full Text Available Book ReviewJudul buku    : The Living CompanyPenulis    : Arie de GeusPengantar    : Peter M. SengePenerbit    : Harvard Business School PressTahun terbit    : 1997Tebal    : xiv + 214 hal

  9. Live chat alternative security protocol

    Science.gov (United States)

    Rahman, J. P. R.; Nugraha, E.; Febriany, A.

    2018-05-01

    Indonesia is one of the largest e-commerce markets in Southeast Asia, as many as 5 million people do transactions in e-commerce, therefore more and more people use live chat service to communicate with customer service. In live chat, the customer service often asks customers’ data such as, full name, address, e-mail, transaction id, which aims to verify the purchase of the product. One of the risks that will happen is sniffing which will lead to the theft of confidential information that will cause huge losses to the customer. The anticipation that will be done is build an alternative security protocol for user interaction in live chat by using a cryptographic algorithm that is useful for protecting confidential messages. Live chat requires confidentiality and data integration with encryption and hash functions. The used algorithm are Rijndael 256 bits, RSA, and SHA256. To increase the complexity, the Rijndael algorithm will be modified in the S-box and ShiftRow sections based on the shannon principle rule, the results show that all pass the Randomness test, but the modification in Shiftrow indicates a better avalanche effect. Therefore the message will be difficult to be stolen or changed.

  10. Our Lives with Electric Things

    DEFF Research Database (Denmark)

    Schick, Lea

    2017-01-01

    Our lives with electric things are positively charged with meaning. Our bodies pulse with electrical activity. The electric appliances, devices, and technologies around us bring hope and anxiety, possibility and danger. Some have transformed our possibilities for reproducing, nurturing, and susta......Our lives with electric things are positively charged with meaning. Our bodies pulse with electrical activity. The electric appliances, devices, and technologies around us bring hope and anxiety, possibility and danger. Some have transformed our possibilities for reproducing, nurturing......, and sustaining life. Some mediate human sociality across time and space, while others knit ecological and interspecies relationships together. Still others create possibilities for controlling, managing, exploiting, and ending life. Against this backdrop any anthropology of electricity seems to require electric...... things. Can we still imagine the possibility of lives without electric things? Can electric things help us to address the possibilities and limits of life with electricity? Can our lives with electricity ever be disentangled from electric things? What are the unique capacities and material politics...

  11. The Living Rainforest Sustainable Greenhouses

    NARCIS (Netherlands)

    Bot, G.P.A.; Zwart, de H.F.; Hansen, K.; Logan, A.; Witte Groenholland, H.

    2008-01-01

    The Living Rainforest (www.livingrainforest.org) is an educational charity that uses rainforest ecology as a metaphor for communicating general sustainability issues to the public. Its greenhouses and office buildings are to be renovated using the most sustainable methods currently available. This

  12. Where You Live: Risk Assessment

    Science.gov (United States)

    Where you live page shows visitors to the risk assessment website how to contact their local regional office by state. Since these link to pages maintained by the local offices they will have the most up-to-date contact information.

  13. Are trees long-lived?

    Science.gov (United States)

    Kevin T. Smith

    2009-01-01

    Trees and tree care can capture the best of people's motivations and intentions. Trees are living memorials that help communities heal at sites of national tragedy, such as Oklahoma City and the World Trade Center. We mark the places of important historical events by the trees that grew nearby even if the original tree, such as the Charter Oak in Connecticut or...

  14. Living with wildfire in Colorado

    Science.gov (United States)

    Patricia A. Champ; Nicholas Flores; Hannah Brenkert-Smith

    2010-01-01

    In this presentation, we describe results of a survey to homeowners living in wildfire-prone areas of two counties along the Front Range of the Rocky Mountains in Colorado. The survey was designed to elicit information on homeowners' experience with wildfire, perceptions of wildfire risk on their property and neighboring properties, mitigation efforts undertaken...

  15. Living History: Elsworth R. Buskirk

    Science.gov (United States)

    Tipton, Charles M.

    2009-01-01

    In 2005, the American Physiological Society (APS) initiated the Living History of Physiology Archival Program to recognize senior members who have made significant contributions during their career to the advancement of the discipline and the profession of physiology. Subsequently, the leadership of the APS Section of Environmental and Exercise…

  16. Living History: Clark M. Blatteis

    Science.gov (United States)

    Quan, Ning

    2009-01-01

    In 2005, the American Physiological Society (APS) initiated the Living History Project to recognize senior members who have made extraordinary contributions during their career to the advancement of the discipline and profession of physiology. During 2007, the APS Section of Environmental and Exercise Physiology selected Clark M. Blatteis to be…

  17. Drivers of Live Cattle Price in the Livestock Trading System of Central Cameroon

    Science.gov (United States)

    Motta, Paolo; Handel, Ian G.; Rydevik, Gustaf; Hamman, Saidou M.; Ngwa, Victor Ngu; Tanya, Vincent N.; Morgan, Kenton L.; Bronsvoort, Barend M. deC.; Porphyre, Thibaud

    2018-01-01

    Livestock production and trade are critical for the food security and welfare of rural households in sub-Saharan Africa. In Cameroon, animal trade consists mainly of live cattle commercialized through livestock markets. Identifying the factors contributing to cattle price formation is critical for designing effective policies for sustainable production and for increasing food availability. In this study, we evaluated the influence of a range of individual- and market-level factors on the price of cattle that were sold in all transactions (n = 118,017) recorded over a 12-month period from 31 livestock markets in the main cattle production area of the country. An information-theoretic approach using a generalized additive mixed-effect model was implemented to select the best explanatory model as well as evaluate the robustness of the identified drivers and the predictive ability of the model. The age and gender of the cattle traded were consistently found to be important drivers of the price (p livestock market and the price of the traded live cattle (p < 0.01). Although our analysis did not account for factors informing on specific phenotypic traits nor breed characteristics of cattle traded, nearly 50% of the observed variation in live cattle prices was explained by the final model. Ultimately, our model gives a large scale overview of drivers of cattle price formation in Cameroon and to our knowledge is the first study of this scale in Central Africa. Our findings represent an important milestone in designing efficient and sustainable animal health management programme in Cameroon and ensure livelihood sustainability for rural households. PMID:29387687

  18. Living Shoreline Designs in Urban Systems: Examples from New York and Baltimore Harbors

    Science.gov (United States)

    Doss, T.

    2017-12-01

    In the aftermath of Hurricanes Irene and Sandy, there was a renewed interest in protecting our shorelines and restoring community resiliency by using natural and nature based features. We observed in the wake of these storms that those shorelines that had been protected by natural features sustained less damage. But how well can we mimic these natural features? And how do we determine which strategy is best along a given shoreline? A series of living shoreline pilot projects are presented, highlighting the design and construction for the different strategies and how they are being monitored and adapted to sea level rise.

  19. Face Liveness Detection Using Defocus

    Directory of Open Access Journals (Sweden)

    Sooyeon Kim

    2015-01-01

    Full Text Available In order to develop security systems for identity authentication, face recognition (FR technology has been applied. One of the main problems of applying FR technology is that the systems are especially vulnerable to attacks with spoofing faces (e.g., 2D pictures. To defend from these attacks and to enhance the reliability of FR systems, many anti-spoofing approaches have been recently developed. In this paper, we propose a method for face liveness detection using the effect of defocus. From two images sequentially taken at different focuses, three features, focus, power histogram and gradient location and orientation histogram (GLOH, are extracted. Afterwards, we detect forged faces through the feature-level fusion approach. For reliable performance verification, we develop two databases with a handheld digital camera and a webcam. The proposed method achieves a 3.29% half total error rate (HTER at a given depth of field (DoF and can be extended to camera-equipped devices, like smartphones.

  20. The Biosphere as a Living System. On the Harmonization of Human and Biosphere Relationship

    Directory of Open Access Journals (Sweden)

    Alexey Yablokov

    2017-02-01

    bioshere’ systems, and based on the concept of controlled evolution (at first stages of crisis governance, to assist nature to restore the disturbed natural regulations of biospheric processes. For this it need to find out what the thresholds (“planetary bounders” for allowable violations of natural processes are already accomplished, and develop a plan of action for the reduction of disturbances, relying on the regenerative potential of living nature and resources of the human mind.

  1. Living science: Science as an activity of living beings.

    Science.gov (United States)

    MacLennan, Bruce J

    2015-12-01

    The philosophy of science should accommodate itself to the facts of human existence, using all aspects of human experience to adapt more effectively, as individuals, species, and global ecosystem. This has several implications: (1) Our nature as sentient beings interacting with other sentient beings requires the use of phenomenological methods to investigate consciousness. (2) Our embodied, situated, purposeful physical interactions with the world are the foundation of scientific understanding. (3) Aristotle's four causes are essential for understanding living systems and, in particular, the final cause aids understanding the role of humankind, and especially science, in the global ecosystem. (4) In order to fulfill this role well, scientists need to employ the full panoply of human faculties. These include the consciousness faculties (thinking, sensation, feeling, intuition), and therefore, as advocated by many famous scientists, we should cultivate our aesthetic sense, emotions, imagination, and intuition. Our unconscious faculties include archetypal structures common to all humans, which can guide scientific discovery. By striving to engage the whole of human nature, science will fulfill better its function for humans and the global ecosystem. Copyright © 2015. Published by Elsevier Ltd.

  2. Don Quixote an Celia: the desire to live other lives

    Directory of Open Access Journals (Sweden)

    María Jesús Fraga Fernández-Cuevas

    2012-12-01

    Full Text Available The present study explores the parallelisms between Don Quixote and Elena Fortun’s novels Celia. First, it enumerates the various activities that prove the author’s interest in Cervantes and his work, as well as the possible intervention of her mentor, Maria Martinez Sierra, in the genesis of the child’s character. Both novels, of dialogical nature, share an episodic structure articulated by a weak storyline. Its protagonists are animated by the desire to live the lives of the characters of their favorite readings. They confuse fantasy and reality causing situations whose results are almost always adverse. If Don Quixote dies back to the reason, so will Celia, the girl, with her entry into adulthood by resigning her fantasies, which will be taken up by new generations of children.

  3. Enhanced living environments from models to technologies

    CERN Document Server

    Dobre, Ciprian; Ganchev, Ivan; Garcia, Nuno; Goleva, Rossitza Ivanova

    2017-01-01

    Enhanced living environments employ information and communications technologies to support true ambient assisted living for people with disabilities. This book provides an overview of today's architectures, techniques, protocols, components, and cloud-based solutions related to ambient assisted living and enhanced living environments.

  4. Piloted ignition of live forest fuels

    Science.gov (United States)

    S. McAllister; I. Grenfell; A. Hadlow; W. M. Jolly; M. Finney; J. Cohen

    2012-01-01

    The most unpredictable and uncontrollable wildfires are those that burn in the crowns of live vegetation. The fuels that feed these crown fires are mostly live, green foliage. Unfortunately, little is known about how live fuels combust. To understand how live fuels burn, piloted ignition experiments were performed with lodgepole pine and Douglas-fir. The thermal...

  5. Decision support systems for power plants impact on the living standard

    International Nuclear Information System (INIS)

    Chatzimouratidis, Athanasios I.; Pilavachi, Petros A.

    2012-01-01

    Highlights: ► Ten major types of power plant are evaluated as to their impact on living standard. ► Uncertainty in both criteria performance and criteria weighting is considered. ► PROMETHEE II method, 12 criteria and 13 scenarios are used. ► Results are presented per scenario and per type of power plant. ► Optimal solution depends on scenario assumptions of the decision maker. - Abstract: In developed countries, the quality of life is of first priority and an overall assessment of power plant impact on the living standard requires a multicriteria analysis of both positive and negative factors incorporating uncertainty in criteria performance and probability assessment of weighting factors. This study incorporates PROMETHEE II to assess 10 major types of power plant under 12 criteria, 13 fixed and infinite customized probability assessed weight set scenarios. The power plants considered are coal/lignite, oil, natural gas turbine, natural gas combined cycle, nuclear, hydro, wind, photovoltaic, biomass and geothermal. Geothermal, wind and photovoltaic power plants are excellent choices in most of the cases and biomass and hydro should also be preferred to nuclear and fossil fuel. Among nuclear and fossil fuel the choice is based on the specific parameters of each case examined while natural gas technologies have specific advantages. The motivation of this study was to provide a tool for the decision-maker to evaluate all major types of power plant incorporating multicriteria and customized probability assessment of weighting factors.

  6. 'Living between two worlds': who is living in whose worlds?

    Science.gov (United States)

    McCoy, Brian

    2009-08-01

    Indigenous people have often been depicted as 'living between two worlds'. They have been described as living neither in their 'Indigenous' world nor in the 'Western' world but in some middle, liminal, or in-between 'world'. People in such situations are often described as 'caught' or 'suspended' and with obvious negative social, emotional and health consequences. What is this cultural space that is often described as 'being between two worlds'? Can Indigenous people develop their identity within the demands and values of contemporary Australian society? Most people who live within the context of modernity move across a mixture of different social, spiritual and cultural 'worlds'. By projecting particular and negative meanings onto Indigenous people and their journey of identity, non-Indigenous people diminish the value of Indigenous energies and initiatives in attempting to cope with life's diverse pressures and expectations. The perpetuation of such attitudes serves to undermine the efforts that Indigenous people make to engage modernity while at the same time attempting to maintain values that are of critical importance for their health and wellbeing. Consequently, non-Indigenous people can end up diminishing the importance of their own life transitions.

  7. Women's lives in times of Zika: mosquito-controlled lives?

    Science.gov (United States)

    Linde, Ana Rosa; Siqueira, Carlos Eduardo

    2018-05-10

    Zika virus infection during pregnancy is a cause of congenital brain abnormalities. Its consequences to pregnancies has made governments, national and international agencies issue advices and recommendations to women. There is a clear need to investigate how the Zika outbreak affects the decisions that women take concerning their lives and the life of their families, as well as how women are psychologically and emotionally dealing with the outbreak. We conducted a qualitative study to address the impact of the Zika epidemic on the family life of women living in Brazil, Puerto Rico, and the US, who were affected by it to shed light on the social repercussions of Zika. Women were recruited through the snowball sampling technique and data was collected through semi-structured interviews. We describe the effects in mental health and the coping strategies that women use to deal with the Zika epidemic. Zika is taking a heavy toll on women's emotional well-being. They are coping with feelings of fear, helplessness, and uncertainty by taking drastic precautions to avoid infection that affect all areas of their lives. Coping strategies pose obstacles in professional life, lead to social isolation, including from family and partner, and threaten the emotional and physical well-being of women. Our findings suggest that the impacts of the Zika epidemic on women may be universal and global. Zika infection is a silent and heavy burden on women's shoulders.

  8. How Live Performance Moves the Human Heart.

    Directory of Open Access Journals (Sweden)

    Haruka Shoda

    Full Text Available We investigated how the audience member's physiological reactions differ as a function of listening context (i.e., live versus recorded music contexts. Thirty-seven audience members were assigned to one of seven pianists' performances and listened to his/her live performances of six pieces (fast and slow pieces by Bach, Schumann, and Debussy. Approximately 10 weeks after the live performance, each of the audience members returned to the same room and listened to the recorded performances of the same pianists' via speakers. We recorded the audience members' electrocardiograms in listening to the performances in both conditions, and analyzed their heart rates and the spectral features of the heart-rate variability (i.e., HF/TF, LF/HF. Results showed that the audience's heart rate was higher for the faster than the slower piece only in the live condition. As compared with the recorded condition, the audience's sympathovagal balance (LF/HF was less while their vagal nervous system (HF/TF was activated more in the live condition, which appears to suggest that sharing the ongoing musical moments with the pianist reduces the audience's physiological stress. The results are discussed in terms of the audience's superior attention and temporal entrainment to live performance.

  9. The Nature of Living Systems: An Exposition of the Basic Concepts in General Systems Theory.

    Science.gov (United States)

    Miller, James G.

    General systems theory is a set of related definitions, assumptions, and propositions which deal with reality as an integrated hierarchy of organizations of matter and energy. In this paper, the author defines the concepts of space, time, matter, energy, and information in terms of their meaning in general systems theory. He defines a system as a…

  10. An Assistive Technology System that Provides Personalized Dressing Support for People Living with Dementia: Capability Study.

    Science.gov (United States)

    Burleson, Winslow; Lozano, Cecil; Ravishankar, Vijay; Lee, Jisoo; Mahoney, Diane

    2018-05-01

    Individuals living with advancing stages of dementia (persons with dementia, PWDs) or other cognitive disorders do not have the luxury of remembering how to perform basic day-to-day activities, which in turn makes them increasingly dependent on the assistance of caregivers. Dressing is one of the most common and stressful activities provided by caregivers because of its complexity and privacy challenges posed during the process. In preparation for in-home trials with PWDs, the aim of this study was to develop and evaluate a prototype intelligent system, the DRESS prototype, to assess its ability to provide automated assistance with dressing that can afford independence and privacy to individual PWDs and potentially provide additional freedom to their caregivers (family members and professionals). This laboratory study evaluated the DRESS prototype's capacity to detect dressing events. These events were engaged in by 11 healthy participants simulating common correct and incorrect dressing scenarios. The events ranged from donning a shirt and pants inside out or backwards to partial dressing-typical issues that challenge a PWD and their caregivers. A set of expected detections for correct dressing was prepared via video analysis of all participants' dressing behaviors. In the initial phases of donning either shirts or pants, the DRESS prototype missed only 4 out of 388 expected detections. The prototype's ability to recognize other missing detections varied across conditions. There were also some unexpected detections such as detection of the inside of a shirt as it was being put on. Throughout the study, detection of dressing events was adversely affected by the relatively smaller effective size of the markers at greater distances. Although the DRESS prototype incorrectly identified 10 of 22 cases for shirts, the prototype preformed significantly better for pants, incorrectly identifying only 5 of 22 cases. Further analyses identified opportunities to improve the

  11. Measurements of half-lives of short-lived nuclides

    International Nuclear Information System (INIS)

    Elmali, A.

    2001-01-01

    In this work 19 F(n,p) 19 O (26.94 sec.), 76 Ge(n,2n) 75m Ge(47.73 sec.), 23 Na(n,p) 23 Ne (37.24 sec.) 23 Na(n,α) 20 F (11.12 sec.), 68 Zn(n,p) 68g Cu (31.11 sec.), 46 Ti(n,P) 46m Sc (18.70 sec.), 19 F(n,α) 16 N (7.13 sec.) and 92 Mo(n,2n) 91m Mo (65.40 sec.) half lives were determined. The half life measurements were performed utilizing the Sames T-400 neutron generator at the Physics Department of Cekmece Nuclear Research and Training Center, Istanbul. Fast neutrons (∼ 14 MeV) were produced via T(d,n)He reaction in a TIT target which was bombarded by 300 KeV deuterons. The samples bombarded with 14 MeV neutrons were transferred with a fast sample transport system from neutron source to the HPGe detector were the gamma measurements are performed. The time elapsed during the transport of the sample between the two stations were about 0.5 sec. in the experimental data, corrections were made for coincidence summing, pules pile up, dead time and background elimination. In order to test the accuracy and the sensitivity of the half-life measurement system used in this work, the 19 O half life form the 19 F(n,p) 19 O reaction were measured first and compared with the data given in a recently published JAERI report

  12. Perspectives on Living With Fibromyalgia

    Directory of Open Access Journals (Sweden)

    Ann Gill Taylor

    2016-07-01

    Full Text Available Perceptions of people living with chronic illness change over time, contributing to health-related stress that necessitates coping skills. Paterson’s shifting perspectives model provides an explanation of chronically ill people’s variations in attention to their symptoms. In this qualitative study, 20 people with fibromyalgia living in a rural setting were interviewed in 2013 with the aim of gaining insight into their experiences and the meaning-making associated with their chronic condition. Analysis of the interview data categorized five recurrent, or common, themes: experiences of loss, feelings of fear and uncertainty, influence of stress, stigmatization of the disease, and coping through courage. Difficulties attendant to losses, distress, and stigma associated with this chronic condition led the participants to report poor health-related quality of life. The study findings can be useful across clinical settings to nurses and other health care providers in understanding those diagnosed with fibromyalgia and their care needs.

  13. Living in a Flexible Space

    Science.gov (United States)

    Canepa, Simona

    2017-10-01

    How long does a space or an object have to last? If in the past an object or a building manufacturing was designed to last as much as possible, nowadays it is designed to have a life related to the time in which it will be used. Flexibility is what characterizes a space, it’s the ability to be variable and adaptable to changes in the lives of users or in relation to the use which these will make over time. The evolution of the labour market, the difficulty of inserting within it and the need to push more and more frequent move today in the trial of living space models increasingly flexible: people, especially young people, are forced to move on territory outlining a new condition to which the flexible nomadic dwellings offer an adequate response, ensuring high functional performance in confined spaces.

  14. Living your own life, together

    DEFF Research Database (Denmark)

    Westerling, Allan

    This paper discusses the impact of modernization and individualization on family life. It does so by tracing changes in configurations of family life and social networks between 2003 and 2014, and by analyzing transformations of social practices of everyday life. Initial findings from this study...... the configuration of the individual/social relationship in everyday family life. The paper examines the concepts about the ‘post familial family’ as well as ‘the network family’ and their usefulness in the study of contemporary family practices....... show that 81% of the respondents who lived with a partner in 2014 lived with the same partner in 2003. This paper analyzes this stability in couple relationship. The empirical focus is on social and emotional support, on the character of the social networks as well as gender equality among partners...

  15. Social Work and Lived Citizenship

    DEFF Research Database (Denmark)

    Warming, Hanne; Fahnøe, Kristian

    2017-01-01

    Warming and Fahnøe offers, through introduction of the sensitising concept of lived citizenship and a socio-spatial perspective, a much needed renewal of the rights and strength based approach to social work practice and research towards an almost anthropological understanding of the social...... of meaning and power as (re-) producing practices through which clients experience and negotiate rights, responsibilities, participation, identity and belonging, and thereby of dynamics of inclusion and exclusion related to social work....... situation of vulnerable groups. Indeed, they show how the concept of lived citizenship, and four supporting concepts (disciplinary versus inclusive identity shaping; intimate citizenship; space; community governance) enables contextualized analyses of the complexities of social work as a social space...

  16. Living with HIV: Patients Perspective

    Centers for Disease Control (CDC) Podcasts

    2009-06-04

    This podcast showcases three people who are living with HIV. The patients share their experiences of being diagnosed with HIV, of the treatments they are undergoing, and on taking responsibility for their health.  Created: 6/4/2009 by Division of HIV and AIDS Prevention (DHAP), National Center for HIV, Hepatitis, STD, and Tuberculosis Prevention ( NCHHSTP).   Date Released: 6/4/2009.

  17. NPP Krsko Living PSA Concept

    International Nuclear Information System (INIS)

    Vrbanic, I.; Spiler, J.

    2000-01-01

    NPP Krsko developed PSA model of internal and external initiators within the frame of the Individual Plant Examination (IPE) project. Within this project PSA model was used to examine the existing plant design features. In order to continue with use of this PSA model upon the completion of IPE in various risk-informed applications in support of plant operation and evaluations of design changes, an appropriate living PSA concept needed to be defined. The Living PSA concept is in NPP Krsko considered as being a set of activities pursued in order to update existing PSA model in a manner that it appropriately represents the plant design, operation practice and history. Only a PSA model which is being updated in this manner can serve as a platform for plant-specific risk informed applications. The NPP Krsko living PSA concept is based on the following major ponts. First, the baseline PSA model is defined, which is to be maintained and updated and which is to be reference point for any risk-informed application. Second, issues having a potential for impact on baseline PSA model are identified and procedure and responsibilities for their permanent monitoring and evaluation are established. Third, manner is defined in which consequential changes to baseline PSA model are implemented and controlled, together with associated responsibilities. Finally, the process is defined by which the existing version of baseline PSA model is superseded by a new one. Each time a new version of baseline PSA model is released, it would be re-quantified and the results evaluated and interpreted. By documenting these re-quantifications and evaluations of results in a sequence, the track is being kept of changes in long-term averaged risk perspective, represented by long-term averaged frequencies of core damage and pre-defined release categories. These major topics of NPP Krsko living PSA concept are presented and discussed in the paper. (author)

  18. Living related donor liver transplantation.

    Science.gov (United States)

    Chen, C L; Chen, Y S; Liu, P P; Chiang, Y C; Cheng, Y F; Huang, T L; Eng, H L

    1997-10-01

    Living related liver transplantation (LRLT) has been developed in response to the paediatric organ donor shortage. According to the International Living Donor Registry, 521 transplants had been performed in 515 patients between December 8 1988 and January 19 1996 in 30 centres worldwide. The overall actuarial patient and graft survival rates were 82.7 and 80%, respectively. Between June 17 1994 and November 30 1996, the authors performed 11 LRLT at the Chung Gung Memorial Hospital. The living donors consisted of 10 mothers and one father. The mean graft weight was 303 g and the mean graft recipient weight ratio was 2.2%. Donor hepatectomy was performed without vascular inflow occlusion. The intra-operative blood loss ranged from 30 mL to 120 mL with an average of 61 mL, and blood transfusion was not required in all donors both intra-operatively and during the postoperative period. Underlying diseases of the recipients were biliary atresia (n = 10) and glycogen storage disease (n = 1). The mean graft cold ischaemia time was 106 min, the mean second warm ischaemia time was 51 min and the mean interval between portal and arterial reperfusion was 81 min. The initial LRLT results were promising with all donors having been discharged without complication. The recipients experienced a few complications, all of which were manageable with early intervention. All 11 recipients are alive and well. These are encouraging results and the authors hope to expand the use of live donors for liver transplantation to cope with demand.

  19. Blurriness in Live Forensics: An Introduction

    Science.gov (United States)

    Savoldi, Antonio; Gubian, Paolo

    The Live Forensics discipline aims at answering basic questions related to a digital crime, which usually involves a computer-based system. The investigation should be carried out with the very goal to establish which processes were running, when they were started and by whom, what specific activities those processes were doing and the state of active network connections. Besides, a set of tools needs to be launched on the running system by altering, as a consequence of the Locard’s exchange principle [2], the system’s memory. All the methodologies for the live forensics field proposed until now have a basic, albeit important, weakness, which is the inability to quantify the perturbation, or blurriness, of the system’s memory of the investigated computer. This is the very last goal of this paper: to provide a set of guidelines which can be effectively used for measuring the uncertainty of the collected volatile memory on a live system being investigated.

  20. Dynamical Detection of Topological Phase Transitions in Short-Lived Atomic Systems

    Science.gov (United States)

    Setiawan, F.; Sengupta, K.; Spielman, I. B.; Sau, Jay D.

    2015-11-01

    We demonstrate that dynamical probes provide direct means of detecting the topological phase transition (TPT) between conventional and topological phases, which would otherwise be difficult to access because of loss or heating processes. We propose to avoid such heating by rapidly quenching in and out of the short-lived topological phase across the transition that supports gapless excitations. Following the quench, the distribution of excitations in the final conventional phase carries signatures of the TPT. We apply this strategy to study the TPT into a Majorana-carrying topological phase predicted in one-dimensional spin-orbit-coupled Fermi gases with attractive interactions. The resulting spin-resolved momentum distribution, computed by self-consistently solving the time-dependent Bogoliubov-de Gennes equations, exhibits Kibble-Zurek scaling and Stückelberg oscillations characteristic of the TPT. We discuss parameter regimes where the TPT is experimentally accessible.

  1. A metaphysics of living systems: the Yōga-Vāsistha view.

    Science.gov (United States)

    Narasimha, Roddam

    2002-12-01

    The Yōga-Vāsistha is a rich and complex philosophical 'poem' (kāvya) of epic length, written in classical Sanskrit by an unknown author some time between the 6th and 13th centuries CE, probably around the 7th century. It is notable for its eloquent praise of self-effort and enquiry or analysis, and for its severe disparagement of the notion of fate. It views consciousness as (a) characterizing all living forms (including plant and insect life), (b) being atomic, and (c) analogous to the emergence of waves and whirlpools in water; it therefore grapples with what today would be called the problems of reductionism and emergentism. Notions of the survival of the fittest, and of a dynamic process of creation and loss, are expressed with characteristic force. The paper presents a selection of verses (in an English translation) setting forth these views, and a brief analysis of their implications.

  2. Applicability of living PSA in NPP modernization

    International Nuclear Information System (INIS)

    Himanen, R.

    1999-01-01

    Recently the utility Teollisuuden Voima Oy (TVO) has modernized the Olkiluoto 1 and 2 nuclear units and increased the net electric power by 18 per cent. Level 2 PSA was performed during the modernization project and the living level 1 PSA was used to support the design of the plant modifications. The plant specific living PSA model was a powerful tool when evaluating modernization alternatives. Successive support of safety management with the PSA model requires, that both the utility and the Regulatory Body understand capability and limitations of the model in details. TVO has prepared an internal procedure that presents in detail the practices and responsibilities concerning living PSA. The procedure is based on general guidelines and requirements on probabilistic safety analysis of nuclear power plants in Finland, released by the Regulatory Body. Living PSA requires that also the procedure for the use of living PSA is living. The recently published USNRC Regulatory Guides on PSA will be taken into account in the next version of the TVO PSA procedure. The PSA Peer Review Certification Process is one way to evaluate the quality of PSA in general, but also to detect the weaknesses of the PSA. However, the Certification Process cover only limited scope of PSA omitting e.g. all other external events except internal floods. This paper gives an overview on the scope of living PSA for Olkiluoto 1 and 2, and presents some examples on the real use of PSA concerning the modernization of the plant. Definition of quantitative dependability requirements for renovated systems is possible, but on the other hand, proving of these targets is in some cases extremely difficult, because of lacking dependability data. The problems are mainly concerned in systems with of programmable logic control. (au)

  3. Understanding the decline and resilience loss of a long-lived social-ecological system: insights from system dynamics

    Directory of Open Access Journals (Sweden)

    Alicia Tenza

    2017-06-01

    Full Text Available Collapse of social-ecological systems (SESs is a common process in human history. Depletion of natural resources, scarcity of human capital, or both, is/are common pathways toward collapse. We use the system dynamics approach to better understand specific problems of small-scale, long-lived SESs. We present a qualitative (or conceptual model using the conceptualization process of the system dynamics approach to study the dynamics of an oasis in Mexico that has witnessed a dramatic transition to decline in recent decades. We used indepth interviews, participant observation, expert opinions, and official statistical data sets to define the boundaries, and structure in a causal loop diagram of our studied system. We described historical trends and showed the reference mode for the main system variables (observed data, and analyzed the expected system behavior according to the system structure. We identified the main drivers that changed the system structure, as well as structural changes, and the effects of these changes on the dynamics, resilience, and vulnerability of this SES. We found that the tendency of this SES toward collapse was triggered by exogenous factors (growth of modern agriculture in nearby valleys, and socio-political relocation, and was maintained by an endogenous structure. These structural changes weakened the resilience of this SES. One of these changes resulted in a long-term maladaptation of the SES, which increased its vulnerability to frequent system disturbances (hurricanes and droughts. The conceptual model developed provides an in-depth qualitative description of the system, with an important amount of qualitative and quantitative information, to establish the structural hypothesis of the observed behavior. Using this qualitative model, the next research steps are to develop a quantitative model to test the qualitative theories, and to explore future scenarios of system resilience for decision-making processes to

  4. What it takes to understand and cure a living system: computational systems biology and a systems biology-driven pharmacokinetics-pharmacodynamics platform

    NARCIS (Netherlands)

    Swat, Maciej; Kiełbasa, Szymon M.; Polak, Sebastian; Olivier, Brett; Bruggeman, Frank J.; Tulloch, Mark Quinton; Snoep, Jacky L.; Verhoeven, Arthur J.; Westerhoff, Hans V.

    2011-01-01

    The utility of model repositories is discussed in the context of systems biology (SB). It is shown how such repositories, and in particular their live versions, can be used for computational SB: we calculate the robustness of the yeast glycolytic network with respect to perturbations of one of its

  5. Scanning Ion Conductance Microscopy of Live Keratinocytes

    International Nuclear Information System (INIS)

    Hegde, V; Mason, A; Saliev, T; Smith, F J D; McLean, W H I; Campbell, P A

    2012-01-01

    Scanning ion conductance microscopy (SICM) is perhaps the least well known technique from the scanning probe microscopy (SPM) family of instruments. As with its more familiar counterpart, atomic force microscopy (AFM), the technique provides high-resolution topographic imaging, with the caveat that target structures must be immersed in a conducting solution so that a controllable ion current may be utilised as the basis for feedback. In operation, this non-contact characteristic of SICM makes it ideal for the study of delicate structures, such as live cells. Moreover, the intrinsic architecture of the instrument, incorporating as it does, a scanned micropipette, lends itself to combination approaches with complementary techniques such as patch-clamp electrophysiology: SICM therefore boasts the capability for both structural and functional imaging. For the present observations, an ICnano S system (Ionscope Ltd., Melbourn, UK) operating in 'hopping mode' was used, with the objective of assessing the instrument's utility for imaging live keratinocytes under physiological buffers. In scans employing cultured HaCaT cells (spontaneously immortalised, human keratinocytes), we compared the qualitative differences of live cells imaged with SICM and AFM, and also with their respective counterparts after chemical fixation in 4% paraformaldehyde. Characteristic surface microvilli were particularly prominent in live cell imaging by SICM. Moreover, time lapse SICM imaging on live cells revealed that changes in the pattern of microvilli could be tracked over time. By comparison, AFM imaging on live cells, even at very low contact forces (< nN), could not routinely image microvilli: rather, an apparently convolved image of the underlying cytoskeleton was instead prevalent. We note that the present incarnation of the commercial instrument falls some way behind the market leading SPMs in terms of technical prowess and scanning speed, however, the intrinsic non-obtrusive nature of

  6. Safety, Liveness and Run-time Refinement for Modular Process-Aware Information Systems with Dynamic Sub Processes

    DEFF Research Database (Denmark)

    Debois, Søren; Hildebrandt, Thomas; Slaats, Tijs

    2015-01-01

    and verification of flexible, run-time adaptable process-aware information systems, moved into practice via the Dynamic Condition Response (DCR) Graphs notation co-developed with our industrial partner. Our key contributions are: (1) A formal theory of dynamic sub-process instantiation for declarative, event......We study modularity, run-time adaptation and refinement under safety and liveness constraints in event-based process models with dynamic sub-process instantiation. The study is part of a larger programme to provide semantically well-founded technologies for modelling, implementation......-based processes under safety and liveness constraints, given as the DCR* process language, equipped with a compositional operational semantics and conservatively extending the DCR Graphs notation; (2) an expressiveness analysis revealing that the DCR* process language is Turing-complete, while the fragment cor...

  7. Bacterial production and growth rate estimation from [3H]thymidine incorporation for attached and free-living bacteria in aquatic systems

    International Nuclear Information System (INIS)

    Iriberri, J.; Unanue, M.; Ayo, B.; Barcina, I.; Egea, L.

    1990-01-01

    Production and specific growth rates of attached and free-living bacteria were estimated in an oligotrophic marine system, La Salvaje Beach, Vizcaya, Spain, and in a freshwater system having a higher nutrient concentration, Butron River, Vizcaya, Spain. Production was calculated from [methyl- 3 H]thymidine incorporation by estimating specific conversion factors (cells or micrograms of C produced per mole of thymidine incorporated) for attached and free-living bacteria, respectively, in each system. Conversion factors were not statistically different between attached and free-living bacteria: 6.812 x 10 11 and 8.678 x 10 11 μg of C mol -1 for free-living and attached bacteria in the freshwater system, and 1.276 x 10 11 and 1.354 x 10 11 μg of C mol -1 for free-living and attached bacteria in the marine system. Therefore, use of a unique conversion factor for the mixed bacterial population is well founded. However, conversion factors were higher in the freshwater system than in the marine system. This could be due to the different tropic conditions of the two systems. Free-living bacteria contributed the most to production in the two systems (85% in the marine system and 67% in the freshwater system) because of their greater contribution to total biomass. Specific growth rates calculated from production data and biomass data were similar for attached and free-living bacteria

  8. Local effects of living windbreaks

    International Nuclear Information System (INIS)

    Souto, L.F.M.A.R.; Meneses, J.F.

    2004-01-01

    The primary purpose of living windbreaks is the reduction of the wind speed. Changes in the velocity and direction of airflow lead to changes in the microclimate. Microclimate is the result of various interacting factors, most of which can be affected by shelter at detectable levels. The effectiveness of windbreaks depends upon their internal and external structure. The most important structural feature is porosity. Maximum wind reductions are closely related to low porosity. However, barriers with low porosity generate more turbulence to leeward then medium or high ones. The horizontal extent of windbreak effects is proportional to windbreak height (h). Wind reductions are detectable on the windward side of the barrier from 2 h to 5 h, and extend to leeward about 20 h, if significant reductions of the normal wind speed (10% - 30%) occur. The principal effects of natural windbreaks on microclimate are reviewed. These are: wind speed, turbulence and their dependence on the porosity and height of the barrier; solar and thermal radiation around the windbreak; air temperature during the day and at night; humidity and snow deposition. Complementary effects of windbreaks are discussed, such as wind and hydraulic erosion, crop protection and plant growth, livestock protection of buildings and people. Disadvantages of windbreaks result from tree-crop competition and pests. Windbreaks allow the practice of agriculture in many regions of the world, namely on island and coastal areas, which are particularly sensitive due to the high wind speeds and salt content of the wind. Windbreaks contribute to sustainable agricultural systems by maintaining biological diversity and improving the aesthetic value of the landscape. A better understanding of their dynamics will certainly contribute to the improvement of sheltered areas and to the establishment of more efficient windbreaks, with less negative impacts to the countryside

  9. Laparoscopic nephrectomy in live donor

    Directory of Open Access Journals (Sweden)

    Mitre Anuar I.

    2004-01-01

    Full Text Available OBJECTIVE: To present the initial experience of videolaparoscopic nephrectomy in live renal donor. MATERIALS AND METHODS: In the period from April 2000 to August 2003, 50 left nephrectomies in live donor were performed by videolaparoscopy for transplantation. Twenty-eight patients were male (56% and 22 female (44%. Mean age was 37.2 years, and the mean body mass index (BMI was 27.1 kg/m². RESULTS: Mean surgical time was 179.5 minutes, and warm ischemia time of the graft was 3.79 minutes. The mean estimated bleeding was 141 mL. There was no need of blood transfusion or conversion to open surgery. In 42 cases (84%, the vascular portion of the graft was considered good by the recipient's surgical team and in all cases, the ureter was considered of proper size, though in one of them (2% its vascularization was considered improper. The transplanted kidneys produced urine still in the surgical room in 46 of the 50 transplantations considered. In only 2 cases opioid was required for analgesia. In average, 3.1 doses of dipyrone were used for each patient during hospital stay, and hospital discharge occurred, in average, after 3.2 days post-operatively. Two patients required re-operations and one of them evolved to death. CONCLUSIONS: The laparoscopic nephrectomy in live donor for renal transplantation is an alternative to conventional open surgery. In relation to the graft, no alteration, either anatomic or functional, was detected. Though there is already a large documentation in the international literature regarding this procedure, in our setting a prospective randomized study with the usual surgical study is still necessary in order to prove the advantages and disadvantages of the method.

  10. Laparoscopic nephrectomy in live donor

    Directory of Open Access Journals (Sweden)

    Anuar I. Mitre

    2004-02-01

    Full Text Available OBJECTIVE: To present the initial experience of videolaparoscopic nephrectomy in live renal donor. MATERIALS AND METHODS: In the period from April 2000 to August 2003, 50 left nephrectomies in live donor were performed by videolaparoscopy for transplantation. Twenty-eight patients were male (56% and 22 female (44%. Mean age was 37.2 years, and the mean body mass index (BMI was 27.1 kg/m². RESULTS: Mean surgical time was 179.5 minutes, and warm ischemia time of the graft was 3.79 minutes. The mean estimated bleeding was 141 mL. There was no need of blood transfusion or conversion to open surgery. In 42 cases (84%, the vascular portion of the graft was considered good by the recipient's surgical team and in all cases, the ureter was considered of proper size, though in one of them (2% its vascularization was considered improper. The transplanted kidneys produced urine still in the surgical room in 46 of the 50 transplantations considered. In only 2 cases opioid was required for analgesia. In average, 3.1 doses of dipyrone were used for each patient during hospital stay, and hospital discharge occurred, in average, after 3.2 days post-operatively. Two patients required re-operations and one of them evolved to death. CONCLUSIONS: The laparoscopic nephrectomy in live donor for renal transplantation is an alternative to conventional open surgery. In relation to the graft, no alteration, either anatomic or functional, was detected. Though there is already a large documentation in the international literature regarding this procedure, in our setting a prospective randomized study with the usual surgical study is still necessary in order to prove the advantages and disadvantages of the method.

  11. Writing the Live Coding Book

    DEFF Research Database (Denmark)

    Blackwell, Alan; Cox, Geoff; Lee, Sang Wong

    2016-01-01

    This paper is a speculation on the relationship between coding and writing, and the ways in which technical innovations and capabilities enable us to rethink each in terms of the other. As a case study, we draw on recent experiences of preparing a book on live coding, which integrates a wide range...... of personal, historical, technical and critical perspectives. This book project has been both experimental and reflective, in a manner that allows us to draw on critical understanding of both code and writing, and point to the potential for new practices in the future....

  12. Live action role-playing games

    DEFF Research Database (Denmark)

    Tychsen, Anders; Hitchens, Michael; Brolund, Thea

    2006-01-01

    Live action role-playing games share a range of characteristics with massively multi-player online games (MMOGs). Because these games have existed for more than 20 years, players of these games have a substantial amount of experience in handling issues pertinent to MMOGs. Survey and review of live...... action role-playing games, whose participant count can be in the thousands, reveal that features such as size, theme, game master-to-player ratio, and others interact to form complex systems that require several different groups of control tools to manage. The way that these games are managed offers...

  13. Quail and other short-lived birds.

    Science.gov (United States)

    Ottinger, M A

    2001-04-01

    Japanese quail are small galliforms that are migratory and generally live 2 to 3years in the wild. Although there is evidence for other environmental cues, they primarily respond to long daylength for regulation of reproduction. In contrast to the Common Tern, a long-lived sea bird that shows little evidence of reproductive aging, Japanese quail follow a well-defined process of aging with evidence of declining function in reproductive, metabolic, and sensory systems. Our studies focus on neuroendocrine changes associated with reproductive aging in the Japanese quail, with emphasis on the male in order to study both endocrine and behavioral components of reproduction and the process of reproductive aging.

  14. The radiations and the living

    International Nuclear Information System (INIS)

    2004-01-01

    The radiation and the living is divided in five parts: biological radiation effects, early response to ionizing radiation, molecular and cellular effects, external radiotherapy, internal radiotherapy, principles of NMR imaging. About the biological radiation effects, whereas first models of biological effects were based on the sole dose at the cell nucleus, it now appears that the origin of the effects lies in the production of scarce critical events -micro energy-deposits overlapping the DNA. Recent theories have successively examined the role of track-end ionization clusters and of core ionizations in DNA atoms. About the molecular and cellular radiation effects, because of the important role of the DNA molecule, radio-induced DNA lesions are more studied. Many cells are able to respond effectively to the DNA lesions in the minutes, the hours, the days which follow the aggression: early response. This respond can lead, in the case of cells irradiated in mitotic activity, to the stop at critical stages of cell cycle, time to activate the systems of repair of genomic lesions. However, when the badly or not repaired DNA lesions durably persist, this state creates a risk of passage of mutations in the daughter cells. The persistence of these lesions can also engage cells towards processes of cellular death by apoptosis or necrosis. In this lecture will be developed different classes of identified lesions, cellular antioxidant defenses, then the various key molecules involved in the early response after irradiation. The third part devoted to external radiotherapy tell us that radiotherapy is naturally at the edge between medicine and physics. Over the past twenty years, where external radiation therapy moved towards an increased conformation of the dose distribution (conformal therapy), major improvements (extensive use of MRI and PET for tumor imaging and delineation, beam optimization methods to improve the dose distribution, on line imaging) originally came from

  15. High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system.

    Science.gov (United States)

    Donoughe, Seth; Kim, Chiyoung; Extavour, Cassandra G

    2018-04-30

    High-throughput live-imaging of embryos is an essential technique in developmental biology, but it is difficult and costly to mount and image embryos in consistent conditions. Here, we present OMMAwell, a simple, reusable device to easily mount dozens of embryos in arrays of agarose microwells with customizable dimensions and spacing. OMMAwell can be configured to mount specimens for upright or inverted microscopes, and includes a reservoir to hold live-imaging medium to maintain constant moisture and osmolarity of specimens during time-lapse imaging. All device components can be fabricated by cutting pieces from a sheet of acrylic using a laser cutter or by making them with a 3D printer. We demonstrate how to design a custom mold and use it to live-image dozens of embryos at a time. We include descriptions, schematics, and design files for 13 additional molds for nine animal species, including most major traditional laboratory models and a number of emerging model systems. Finally, we provide instructions for researchers to customize OMMAwell inserts for embryos or tissues not described herein. © 2018. Published by The Company of Biologists Ltd.

  16. The Cost of Living in Ancient Greece

    Directory of Open Access Journals (Sweden)

    Roberto Morales Harley

    2014-11-01

    Full Text Available The paper focuses on the most relevant economic aspects of Ancient Greece, more specifically, 5th century BC Athens. It explores the Greek notion of economy, the monetary system, the financial administration and the labor market, in order to contextualize the cost of living. The examples on this matter take into account the products’ costs and the people’s wages.

  17. Smart home for urban Chinese elderly living

    OpenAIRE

    Cheng, J. (Jingwen)

    2014-01-01

    Abstract The purpose of this thesis is to design a new smart home for urban Chinese elderly people in home living environment. This new smart home design has to be integrated all the ICT solutions which based on a literature review was proposed and also with a functional back-end system for data collection, analysis and storage. The literature review p...

  18. Learning to Live Well with Celiac Disease

    Science.gov (United States)

    ... Foundation Celiac Disease Foundation Read More "Celiac Disease" Articles Celiac Disease Changes Everything / What is Celiac Disease? / Symptoms, Diagnosis & Treatment / Four Inches and Seven Pounds… / Learning to Live Well with Celiac Disease / Living Gluten- ...

  19. Live recombinant BHV/BRSV vaccine

    NARCIS (Netherlands)

    Keil, G.M.; Rijsewijk, F.A.M.

    1998-01-01

    The present invention refers to synthetic Bovine Respiratory Syncytium virus genes. Also the invention relates to live attenuated Bovine Herpesvirus recombinants carrying such synthetic genes. Furthermore, the invention relates to vaccines based on these live attenuated recombinants, for the

  20. Live feed culture - Problems and perspectives

    Digital Repository Service at National Institute of Oceanography (India)

    Royan, J.P.

    The importance of live feed in aquaculture is stressed. Organisms currently cultured as live feed are microalgae, turbellarians, tanaidaceans, annelids, brine shrimps, fairy shrimps, rotifers, cladocerans and copepods. Their culture methods...

  1. Oxygen Uptake - Live Hauling of Fish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In certain markets, live fish can be sold for substantially higher prices than fresh dressed fish. A significant live-haul industry has developed in the U.S. and...

  2. Dissolved Oxygen - Live Hauling of Fish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In certain markets, live fish can be sold for substantially higher prices than fresh dressed fish. A significant live-haul industry has developed in the U.S. and...

  3. Living with a depressed person in Denmark

    DEFF Research Database (Denmark)

    Hansen, Jeppe Oute; Buus, Niels

    2013-01-01

    Strategies for coping with the burdens of living with a depressed person affect a family's psychosocial environment.......Strategies for coping with the burdens of living with a depressed person affect a family's psychosocial environment....

  4. Informational Closed-Loop Coding-Decoding Control Concept as the Base of the Living or Organized Systems Theory

    Science.gov (United States)

    Kirvelis, Dobilas; Beitas, Kastytis

    2008-10-01

    The aim of this work is to show that the essence of life and living systems is their organization as bioinformational technology on the base of informational anticipatory control. Principal paradigmatic and structural schemes of functional organization of life (organisms and their systems) are constructed on the basis of systemic analysis and synthesis of main phenomenological features of living world. Life is based on functional elements that implement engineering procedures of closed-loop coding-decoding control (CL-CDC). Phenomenon of natural bioinformational control appeared and developed on the Earth 3-4 bln years ago, when the life originated as a result of chemical and later biological evolution. Informatics paradigm considers the physical and chemical transformations of energy and matter in organized systems as flows that are controlled and the signals as means for purposive informational control programs. The social and technical technological systems as informational control systems are a latter phenomenon engineered by man. The information emerges in organized systems as a necessary component of control technology. Generalized schemes of functional organization on levels of cell, organism and brain neocortex, as the highest biosystem with CL-CDC, are presented. CL-CDC concept expands the understanding of bioinformatics.

  5. Live Fire Range Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-08-01

    The Central Training Academy (CTA) is a DOE Headquarters Organization located in Albuquerque, New Mexico, with the mission to effectively and efficiently educate and train personnel involved in the protection of vital national security interests of DOE. The CTA Live Fire Range (LFR), where most of the firearms and tactical training occurs, is a complex separate from the main campus. The purpose of the proposed action is to expand the LFR to allow more options of implementing required training. The Department of Energy has prepared this Environmental Assessment (EA) for the proposed construction and operation of an expanded Live Fire Range Facility at the Central Training Academy in Albuquerque, New Mexico. Based on the analysis in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment, within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an environmental impact statement is not required and DOE is issuing this Finding of No Significant Impact (FONSI).

  6. The Living Indian Critical Tradition

    Directory of Open Access Journals (Sweden)

    Vivek Kumar Dwivedi

    2010-11-01

    Full Text Available This paper attempts to establish the identity of something that is often considered to be missing – a living Indian critical tradition. I refer to the tradition that arises out of the work of those Indians who write in English. The chief architects of this tradition are Sri Aurobindo, C.D. Narasimhaiah, Gayatri Chakravorty Spivak and Homi K. Bhabha. It is possible to believe that Indian literary theories derive almost solely from ancient Sanskrit poetics. Or, alternatively, one can be concerned about the sad state of affairs regarding Indian literary theories or criticism in English. There have been scholars who have raised the question of the pathetic state of Indian scholarship in English and have even come up with some positive suggestions. But these scholars are those who are ignorant about the living Indian critical tradition. The significance of the Indian critical tradition lies in the fact that it provides the real focus to the Indian critical scene. Without an awareness of this tradition Indian literary scholarship (which is quite a different thing from Indian literary criticism and theory as it does not have the same impact as the latter two do can easily fail to see who the real Indian literary critics and theorists are.

  7. Living probabilistic safety assessment (LPSA)

    International Nuclear Information System (INIS)

    1999-08-01

    Over the past few years many nuclear power plant organizations have performed probabilistic safety assessments (PSAs) to identify and understand key plant vulnerabilities. As a result of the availability of these PSA studies, there is a desire to use them to enhance plant safety and to operate the nuclear stations in the most efficient manner. PSA is an effective tool for this purpose as it assists plant management to target resources where the largest benefit to plant safety can be obtained. However, any PSA which is to be used in this way must have a credible and defensible basis. Thus, it is very important to have a high quality 'living PSA' accepted by the plant and the regulator. With this background in mind, the IAEA has prepared this report on Living Probabilistic Safety Assessment (LPSA) which addresses the updating, documentation, quality assurance, and management and organizational requirements for LPSA. Deficiencies in the areas addressed in this report would seriously reduce the adequacy of the LPSA as a tool to support decision making at NPPs. This report was reviewed by a working group during a Technical Committee Meeting on PSA Applications to Improve NPP Safety held in Madrid, Spain, from 23 to 27 February 1998

  8. Exotic Long-lived Particles

    DEFF Research Database (Denmark)

    Jørgensen, Morten Dam

    A search for hadronising long-lived massive particles at the Large Hadron Collider is conducted with the ATLAS detector. No excess events are found. Based on statistical analysis, upper limits on the production cross section are observed to be between 0.01 pb and 0.006 pb for colour octet particles...... (gluinos) with masses ranging from 300 GeV/c2 to 1400 GeV/c2, and 0.01 pb to 0.004 pb for colour triplet particles (stops and sbottoms) with masses ranging from 200 GeV/c2 to 900 GeV/c2. In the context of Supersymmetry with decoupled sfermion and sboson sectors (Split-SUSY), this gives a lower limit...... on the gluino mass of 989 GeV/c2, and 683 GeV/c2 for the stop mass and 618 GeV/c2 for the sbottom mass. In addition, a new method is presented that improves the speed (b ) estimation for long-lived particles in the ATLAS tile calorimeter with a factor of 7 improvement in resolution at low-b and a factor of 2...

  9. Living well in the Neuropolis

    Science.gov (United States)

    Fitzgerald, Des; Rose, Nikolas; Singh, Ilina

    2016-01-01

    Abstract This paper is about the relationship between cities and brains: it charts the back‐and‐forth between the hectic, stressful lives of urban citizens, and a psychological and neurobiological literature that claims to make such stress both visible and knowable. But beyond such genealogical labour, the paper also asks: what can a sociology concerned with the effects of ‘biosocial’ agencies take from a scientific literature on the urban brain? What might sociology even contribute to that literature, in its turn? To investigate these possibilities, the paper centres on the emergence and description of what it calls ‘the Neuropolis’ – a term it deploys to hold together both an intellectual and scientific figure and a real, physical enclosure. The Neuropolis is an image of the city embedded in neuropsychological concepts and histories, but it also describes an embodied set of (sometimes pathological) relations and effects that take places between cities and the people who live in them. At the heart of the paper is an argument that finding a way to thread these phenomena together might open up new paths for thinking about ‘good’ life in the contemporary city. Pushing at this claim, the paper argues that mapping the relations, histories, spaces, and people held together by this term is a vital task for the future of urban sociology. PMID:27397945

  10. Real goods solar living sourcebook your complete guide to living beyond the grid with renewable energy technologies and sustainable living

    CERN Document Server

    Schaeffer, John

    2014-01-01

    What book would you want if you were stranded on a desert island? Widely regarded as the ""bible"" of off-grid living, Real Goods Solar Living Source Book might be your best choice. With over six hundred thousand copies in print worldwide, it is the most comprehensive resource available for anyone interested in lessening their environmental footprint or increasing their energy independence. The Solar Living Sourcebook, Fourteenth Edition is the ultimate guide to renewable energy, sustainable living, natural and green building, off-grid living, and alternative transporta

  11. Living Free: A Teacher Information Booklet.

    Science.gov (United States)

    Mello, Robin

    This workbook helps adolescents learn how to take charge of their own lives and happiness. The underlying idea is to teach them how to live responsibly. By learning to live responsibly, adolescents have the best chance of avoiding drugs, alcohol, and other addictive behaviors such as overeating and overspending. The workbook explains the steps to…

  12. Live Streaming | Events | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Live Streaming. Watch Academy events live here! There are no live events currently happening. Watch out this space for updates or suscribe to our YouTube channel by clicking here. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year ...

  13. Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

    Science.gov (United States)

    Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

    2015-04-01

    Soil, water, soil microbes, and solar energy are the main sources that sustain life on this planet. Without them working in concert, neither plants nor animals would survive. Considering the efficiency of animal production targets, soil must be protected and improved. Therefore, through our sustainable integrated crop and livestock research, we are studying animal and soil interactions from the soil to the plate. Integrating beef cattle systems into a diverse cropping system is providing a living laboratory for education beyond the traditional classroom setting. To establish the living learning laboratory at the Dickinson Research Extension Center, a five-crop rotation was established that included adapted cool and warm season grasses and broadleaf crops. The crop rotation is: sunflower > hard red spring wheat > fall seeded winter triticale-hairy vetch (hay)/spring seeded 7-species cover crop > Corn (85-95 day varieties) > field pea-barley intercrop. Sunflower and spring wheat are harvested for cash crop income in the rotation. Livestock integration occurs when yearling steers that had previously grazed perennial pastures until mid-August graze field pea-barley and subsequently unharvested corn. Average grazing days for field pea-barley and unharvested corn is 30 and 70 days, respectively. At the end of the grazing period, the yearling steers average 499-544 kg and are moved to a feedlot and fed an additional 75 days until slaughter. Maximizing grazing days and extending the grazing season through integration with the cropping system reduces custom feeding costs and enhances animal profit. Beef cows do not require high quality feed after their calves have been weaned. Therefore, gestating beef cows are an ideal animal to graze cover crops and crop aftermath (residue) after yearling steer grazing and farming operations have been completed. Extending the grazing season for beef cows by grazing cover crops and residues reduces winter feed cost, which is one of the

  14. Evaluation of health alerts from an early illness warning system in independent living.

    Science.gov (United States)

    Rantz, Marilyn J; Scott, Susan D; Miller, Steven J; Skubic, Marjorie; Phillips, Lorraine; Alexander, Greg; Koopman, Richelle J; Musterman, Katy; Back, Jessica

    2013-06-01

    Passive sensor networks were deployed in independent living apartments to monitor older adults in their home environments to detect signs of impending illness and alert clinicians so they can intervene and prevent or delay significant changes in health or functional status. A retrospective qualitative deductive content analysis was undertaken to refine health alerts to improve clinical relevance to clinicians as they use alerts in their normal workflow of routine care delivery to older adults. Clinicians completed written free-text boxes to describe actions taken (or not) as a result of each alert; they also rated the clinical significance (relevance) of each health alert on a scale of 1 to 5. Two samples of the clinician's written responses to the health alerts were analyzed after alert algorithms had been adjusted based on results of a pilot study using health alerts to enhance clinical decision-making. In the first sample, a total of 663 comments were generated by seven clinicians in response to 385 unique alerts; there are more comments than alerts because more than one clinician rated the same alert. The second sample had a total of 142 comments produced by three clinicians in response to 88 distinct alerts. The overall clinical relevance of the alerts, as judged by the content of the qualitative comments by clinicians for each alert, improved from 33.3% of the alerts in the first sample classified as clinically relevant to 43.2% in the second. The goal is to produce clinically relevant alerts that clinicians find useful in daily practice. The evaluation methods used are described to assist others as they consider building and iteratively refining health alerts to enhance clinical decision making.

  15. Short-lasting systemic and regional benefits of early crystalloid infusion after intravenous inoculation of dogs with live Escherichia coli

    Directory of Open Access Journals (Sweden)

    Garrido A.G.

    2005-01-01

    Full Text Available We investigated the systemic and regional hemodynamic effects of early crystalloid infusion in an experimental model of septic shock induced by intravenous inoculation with live Escherichia coli. Anesthetized dogs received an intravenous infusion of 1.2 x 10(10 cfu/kg live E. coli in 30 min. After 30 min of observation, they were randomized to controls (no fluids; N = 7, or fluid resuscitation with lactated Ringer's solution, 16 ml/kg (N = 7 or 32 ml/kg (N = 7 over 30 min and followed for 120 min. Cardiac index, portal blood flow, mean arterial pressure, systemic and regional oxygen-derived variables, blood lactate, and gastric PCO2 were assessed. Rapid and progressive cardiovascular deterioration with reduction in cardiac output, mean arterial pressure and portal blood flow (~50, ~25 and ~70%, respectively was induced by the live bacteria challenge. Systemic and regional territories showed significant increases in oxygen extraction and in lactate levels. Significant increases in venous-arterial (~9.6 mmHg, portal-arterial (~12.1 mmHg and gastric mucosal-arterial (~18.4 mmHg PCO2 gradients were also observed. Early fluid replacement, especially with 32 ml/kg volumes of crystalloids, promoted only partial and transient benefits such as increases of ~76% in cardiac index, of ~50% in portal vein blood flow and decreases in venous-arterial, portal-arterial, gastric mucosal-arterial PCO2 gradients (7.2 ± 1.0, 7.2 ± 1.3 and 9.7 ± 2.5 mmHg, respectively. The fluid infusion promoted only modest and transient benefits, unable to restore the systemic and regional perfusional and metabolic changes in this hypodynamic septic shock model.

  16. Resilience among asylum seekers living with HIV

    Directory of Open Access Journals (Sweden)

    Orton Lois

    2012-10-01

    Full Text Available Abstract Background A small body of evidence demonstrates the challenges faced by migrant communities living with HIV but has yet to consider in-depth the experience of asylum seekers whose residency status is undetermined. The overall aim of our study was to explore the experiences of those who are both living with HIV and seeking asylum. This paper focuses on the stressors precipitated by the HIV diagnosis and by going through the asylum system; as well as participants’ resilience in responding to these stressors and the consequences for their health and wellbeing. Methods We conducted an ethnographic study. Fieldwork took place in the UK between 2008–2009 and included: 350 hours of observation at voluntary services providing support to black and minority ethnic groups living with HIV; 29 interviews and four focus group discussions with those who were seeking asylum and living with HIV; and 15 interviews with their health and social care providers. Data were analysed using the constant comparative method. Results There were three main stressors that threatened participants’ resilience. First, migration caused them to leave behind many resources (including social support. Second, stigmatising attitudes led their HIV diagnosis to be a taboo subject furthering their isolation. Third, they found themselves trapped in the asylum system, unable to influence the outcome of their case and reliant on HIV treatment to stay alive. Participants were, however, very resourceful in dealing with these experiences. Resilience processes included: staying busy, drawing on personal faith, and the support received through HIV care providers and voluntary organisations. Even so, their isolated existence meant participants had limited access to social resources, and their treatment in the asylum system had a profound impact on perceived health and wellbeing. Conclusions Asylum seekers living with HIV in the UK show immense resilience. However, their isolation

  17. Age estimation in the living

    DEFF Research Database (Denmark)

    Tangmose, Sara; Thevissen, Patrick; Lynnerup, Niels

    2015-01-01

    A radiographic assessment of third molar development is essential for differentiating between juveniles and adolescents in forensic age estimations. As the developmental stages of third molars are highly correlated, age estimates based on a combination of a full set of third molar scores...... are statistically complicated. Transition analysis (TA) is a statistical method developed for estimating age at death in skeletons, which combines several correlated developmental traits into one age estimate including a 95% prediction interval. The aim of this study was to evaluate the performance of TA...... in the living on a full set of third molar scores. A cross sectional sample of 854 panoramic radiographs, homogenously distributed by sex and age (15.0-24.0 years), were randomly split in two; a reference sample for obtaining age estimates including a 95% prediction interval according to TA; and a validation...

  18. Living with Mentally Ill Parent

    Directory of Open Access Journals (Sweden)

    Kadriye Buldukoglu

    2011-12-01

    Full Text Available The present review seeks to identify and analyze qualitative studies that examined experiences of children whose parents have a mental illness. This study reported that children whose parents have a mental illness had some common experiences. These experiences may have negative effects on children’s coping skills, resilience to tough living conditions and ability to maintain their mental health. In spite of these negative conditions, some of these children have much more self-confidence, resilience and independence because of inner development and early maturation. Some effective intervention programs are needed to promote information to children and other family members about mental illness, coping behaviors. Availability of such psychiatric services and nation-wide programs with professionals to deal with these problems should be organized properly to increase quality of life of these children. Furthermore, qualitative researches that explore the experiences of children whose parents with mental illness should also be conducted in our country.

  19. Living with a parastomal bulge

    DEFF Research Database (Denmark)

    Krogsgaard, Marianne; Thomsen, Thordis; Vinther, Anders

    2017-01-01

    was performed using a phenomenological-hermeneutic approach. FINDINGS: The bulge caused different unfamiliar bodily sensations that interacted with patients' everyday lives. Some but not all of these sensations were modifiable. As the bulge and the ostomy changed size and shape, patients had to adjust...... and readjust stoma care continuously. The physical change called for patients' awareness and posed a threat to patients' control of the ostomy and challenged stoma self-care. The bulge caused a bodily asymmetry that deformed the patients' bodies in a way that exceeded the perceived alteration already caused...... is limited and highly warranted to improve clinical outcome. RELEVANCE TO CLINICAL PRACTICE: The ever-changing bulge posed a threat to patients' control of the ostomy and required specific care from the stoma therapist. Needs-based access to counselling, advice and supplementary materials is important....

  20. Association of cardiovascular system medications with cognitive function and dementia in older adults living in nursing homes in Australia.

    Science.gov (United States)

    Liu, Enwu; Dyer, Suzanne M; O'Donnell, Lisa Kouladjian; Milte, Rachel; Bradley, Clare; Harrison, Stephanie L; Gnanamanickam, Emmanuel; Whitehead, Craig; Crotty, Maria

    2017-06-01

    To examine associations between cardiovascular system medication use with cognition function and diagnosis of dementia in older adults living in nursing homes in Australia. As part of a cross-sectional study of 17 Australian nursing homes examining quality of life and resource use, we examined the association between cognitive impairment and cardiovascular medication use (identified using the Anatomical Therapeutic Classification System) using general linear regression and logistic regression models. People who were receiving end of life care were excluded. Participants included 541 residents with a mean age of 85.5 years (± 8.5), a mean Psychogeriatric Assessment Scale-Cognitive Impairment (PAS-Cog) score of 13.3 (± 7.7), a prevalence of cardiovascular diseases of 44% and of hypertension of 47%. Sixty-four percent of participants had been diagnosed with dementia and 72% had received cardiovascular system medications within the previous 12 months. Regression models demonstrated the use of cardiovascular medications was associated with lower (better) PAS-Cog scores [Coefficient (β) = -3.7; 95% CI: -5.2 to -2.2; P cardiovascular system medication use and better cognitive status among older adults living in nursing homes. In this population, there may be differential access to health care and treatment of cardiovascular risk factors. This association warrants further investigation in large cohort studies.

  1. Development of a dual joystick-controlled laser trapping and cutting system for optical micromanipulation of chromosomes inside living cells.

    Science.gov (United States)

    Harsono, Marcellinus S; Zhu, Qingyuan; Shi, Linda Z; Duquette, Michelle; Berns, Michael W

    2013-02-01

    A multi-joystick robotic laser microscope system used to control two optical traps (tweezers) and one laser scissors has been developed for subcellular organelle manipulation. The use of joysticks has provided a "user-friendly" method for both trapping and cutting of organelles such as chromosomes in live cells. This innovative design has enabled the clean severing of chromosome arms using the laser scissors as well as the ability to easily hold and pull the severed arm using the laser tweezers. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Microcomputer-based systems for automatic control of sample irradiation and chemical analysis of short-lived isotopes

    International Nuclear Information System (INIS)

    Bourret, S.C.

    1974-01-01

    Two systems resulted from the need for the study of the nuclear decay of short-lived radionuclides. Automation was required for better repeatability, speed of chemical separation after irradiation and for protection from the high radiation fields of the samples. A MCS-8 computer was used as the nucleus of the automatic sample irradiation system because the control system required an extensive multiple-sequential circuit. This approach reduced the sequential problem to a computer program. The automatic chemistry control system is a mixture of a fixed and a computer-based programmable control system. The fixed control receives the irradiated liquid sample from the reactor, extracts the liquid and disposes of the used sample container. The programmable control executes the chemistry program that the user has entered through the teletype. (U.S.)

  3. The global need for lived experience leadership.

    Science.gov (United States)

    Byrne, Louise; Stratford, Anthony; Davidson, Larry

    2018-03-01

    Common challenges and experiences of the lived experience/peer workforce globally are considered, with an emphasis on ensuring that future developments both protect and promote the unique lived experience perspective. In the Western world, rapid growth in lived experience roles has led to an urgent need for training and workforce development. However, research indicates the roles risk being coopted without clear lived experience leadership, which is often not occurring. In developing countries and in many Western contexts, the lived experience role has not yet been accepted within the mental health workforce. The need for lived experience leadership to guide these issues is highlighted. Peer-reviewed research, relevant gray literature, and professional experience in countries where little published material currently exists. A window of opportunity currently exists to maximize lived experience leadership, and that window may be closing fast if broad-based actions are not initiated now. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  4. Living arrangements and mental health in Finland

    Science.gov (United States)

    Joutsenniemi, Kaisla; Martelin, Tuija; Martikainen, Pekka; Pirkola, Sami; Koskinen, Seppo

    2006-01-01

    Background Non‐married persons are known to have poor mental health compared with married persons. Health differences between marital status groups may largely arise from corresponding differences in interpersonal social bonds. However, official marital status mirrors the social reality of persons to a decreasing extent, and living arrangements may be a better measure of social bonds. Little is known about mental health in different living arrangement groups. This study aims to establish the extent and determinants of mental health differences by living arrangement in terms of psychological distress (GHQ) and DSM‐IV psychiatric disorders (CIDI). Methods Data were used from the nationally representative cross sectional health 2000 survey, conducted in 2000–1 in Finland. Altogether 4685 participants (80%) aged 30–64 years were included in these analyses; comprehensive information was available on measures of mental health and living arrangements. Living arrangements were measured as follows: married, cohabiting, living with other(s) than a partner, and living alone. Results Compared with the married, persons living alone and those living with other(s) than a partner were approximately twice as likely to have anxiety or depressive disorders. Cohabiters did not differ from the married. In men, psychological distress was similarly associated with living arrangements. Unemployment, lack of social support, and alcohol consumption attenuated the excess psychological distress and psychiatric morbidity of persons living alone and of those living with other(s) than a partner by about 10%–50% each. Conclusions Living arrangements are strongly associated with mental health, particularly among men. Information on living arrangements, social support, unemployment, and alcohol use may facilitate early stage recognition of poor mental health in primary health care. PMID:16698975

  5. Random summing in a multi-detector counting system measuring mixtures of radionuclides of short and long half-lives

    International Nuclear Information System (INIS)

    Oxby, C.B.; Oldroyd, B.; Graham, S.G.

    1979-01-01

    A method is described for correcting a radiation spectrum for the distortion caused by random summing when a multidetector array is used to acquire events from a mixture of radionuclides whose half-lives may be long or short compared with the counting period. With our own counting system it was found that both the resolving time, and the fractions of the energy of a second signal which may be added to that of the immediately previous signal, i.e., the resolving time function, are dependent upon the energies of these two signals. The method requires knowledge of the losses which occur in a multidetector system e.g., live-time error and blocking losses, the variation of the resolving time function with signal energies, a standard spectrum of each radionuclide of the mixture and the fractions of them which constitute the mixture spectrum, the decay constant of each radionuclide, and the fraction of the total events recorded by the system being received by each detector. (orig.)

  6. Some resonances between Eastern thought and Integral Biomathics in the framework of the WLIMES formalism for modeling living systems.

    Science.gov (United States)

    Simeonov, Plamen L; Ehresmann, Andrée C

    2017-12-01

    Forty-two years ago, Capra published "The Tao of Physics" (Capra, 1975). In this book (page 17) he writes: "The exploration of the atomic and subatomic world in the twentieth century has …. necessitated a radical revision of many of our basic concepts" and that, unlike 'classical' physics, the sub-atomic and quantum "modern physics" shows resonances with Eastern thoughts and "leads us to a view of the world which is very similar to the views held by mystics of all ages and traditions." This article stresses an analogous situation in biology with respect to a new theoretical approach for studying living systems, Integral Biomathics (IB), which also exhibits some resonances with Eastern thought. Stepping on earlier research in cybernetics 1 and theoretical biology, 2 IB has been developed since 2011 by over 100 scientists from a number of disciplines who have been exploring a substantial set of theoretical frameworks. From that effort, the need for a robust core model utilizing advanced mathematics and computation adequate for understanding the behavior of organisms as dynamic wholes was identified. At this end, the authors of this article have proposed WLIMES (Ehresmann and Simeonov, 2012), a formal theory for modeling living systems integrating both the Memory Evolutive Systems (Ehresmann and Vanbremeersch, 2007) and the Wandering Logic Intelligence (Simeonov, 2002b). Its principles will be recalled here with respect to their resonances to Eastern thought. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. 5 CFR 845.305 - Ordinary and necessary living expenses.

    Science.gov (United States)

    2010-01-01

    ... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEBT COLLECTION Standards for Waiver... necessary living expenses include rent, mortgage payments, utilities, maintenance, transportation, food...

  8. Feasibility testing of a web-based symptom self-management system for persons living with HIV.

    Science.gov (United States)

    Schnall, Rebecca; Wantland, Dean; Velez, Olivia; Cato, Kenrick; Jia, Haomiao

    2014-01-01

    The purpose of this study was to explore the feasibility of using a Web-based tool to provide tailored symptom management strategies for persons living with HIV (PLWH) and to estimate the effect size of the tool for future studies. Testing the components of the Web-based system was done by incorporating a repeated-measures design measuring the outcomes of symptom frequency and intensity, use of symptom management strategies, and engagement with health care providers. We recruited 42 PLWH; participants were enrolled in the study for 12 weeks and were asked to use the system and complete the questionnaires every 2 weeks. Our results showed that participants who used the strategies were more likely to have a decrease in symptom frequency and intensity. Findings from this feasibility study provide preliminary evidence for the use of a Web-based HIV symptom management tool with self-management strategies for individuals living with HIV infection. Copyright © 2014 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

  9. Exploring a QoS Driven Scheduling Approach for Peer-to-Peer Live Streaming Systems with Network Coding

    Science.gov (United States)

    Cui, Laizhong; Lu, Nan; Chen, Fu

    2014-01-01

    Most large-scale peer-to-peer (P2P) live streaming systems use mesh to organize peers and leverage pull scheduling to transmit packets for providing robustness in dynamic environment. The pull scheduling brings large packet delay. Network coding makes the push scheduling feasible in mesh P2P live streaming and improves the efficiency. However, it may also introduce some extra delays and coding computational overhead. To improve the packet delay, streaming quality, and coding overhead, in this paper are as follows. we propose a QoS driven push scheduling approach. The main contributions of this paper are: (i) We introduce a new network coding method to increase the content diversity and reduce the complexity of scheduling; (ii) we formulate the push scheduling as an optimization problem and transform it to a min-cost flow problem for solving it in polynomial time; (iii) we propose a push scheduling algorithm to reduce the coding overhead and do extensive experiments to validate the effectiveness of our approach. Compared with previous approaches, the simulation results demonstrate that packet delay, continuity index, and coding ratio of our system can be significantly improved, especially in dynamic environments. PMID:25114968

  10. 182Hf, an extinct radionuclide of the early solar system and a possibly live supernova remnant on Earth

    International Nuclear Information System (INIS)

    Vockenhuber, C.; Golser, R.; Kutschera, W.; Priller, A.; Steier, P.; Winkler, S.; Ahmad, I.; Bichler, M.

    2002-01-01

    Full text: The neutron-rich isotope 182 Hf has a half-life of 9 ± 2 million years. It can be used to study the early development of the Earth and the Moon through isotopic anomalies of its stable decay product 182 W. The system 182 Hf - 182 W forms a geochronometer, which offers an excellent way to determine the time-scale for the early Solar System's accretion and the core formation of the planets. Many applications in the last few years yielded impressive results, e.g. concerning the origin of the Moon. However, the half-life of 182 Hf was measured 40 years ago, and a reduction of the large uncertainty would be very desirable. We are engaged in a re-measurement of the half-life, and the current status of this effort will be reported. 182 Hf may also complement a few other radionuclides in the million-year half-life range to trace relatively recent stellar events with high neutron fluxes in the vicinity of the Earth. This may be accomplished by finding measurable traces of live 182 Hf in suitable terrestrial archives. Since 182 Hf has no significant natural sources on earth, live 182 Hf is an ideal indicator of a recent, nearby supernova or other explosive stellar events. The AMS detection method of 182 Hf with the upgraded VERA facility, and first results of this new AMS nuclide will be presented. Refs. 2 (author)

  11. Aging: Learning to Live a Finite Life.

    Science.gov (United States)

    Baars, Jan

    2017-10-01

    Although biodemographic research informs us that life expectancies have risen impressively during the last century, this has not led to much interest in these new horizons of aging. The instrumentalist culture of late modern societies, including its health cure system, has clearly difficulties to relate to the elusive but inevitable limitations of finite life. Moreover, as most people can be expected to survive into old age, thinking about finitude is easily postponed and reserved for those who are "really old." Indeed, a meaningful and realistic understanding of aging needs to include a confrontation with the finitude of life. Instead of reducing aging to the opposite or continuation of vital adulthood, it should be seen as something with a potentially broad and deep significance: a process of learning to live a finite life. As a contribution to this cultural repositioning of aging, the article presents a philosophical exploration of finitude and finite life. Among the discussed topics are the Stoic and Epicurean ways of living with death but also the necessity to expand the meaning of "finitude" beyond mortality. Aging is foremost a process of living through changes that are largely beyond our control although they require active responding. Next, individualistic or existentialist interpretations are criticized because finite lives presuppose a social world in which they emerge and on which they depend. Unfortunately, aging, the most important experiential source of knowledge about what it is to live a finite life, is neglected by the same culture that needs its wisdom. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Living Arrangements of Young Adults in Europe

    Directory of Open Access Journals (Sweden)

    Katrin Schwanitz

    2015-12-01

    Full Text Available Comparative research suggests that there are great cross-national and cross-temporal differences in living arrangements of young adults aged 18-34 in Europe. In this paper, we examine young adults’ living arrangements (1 across several European countries and different national contexts, and (2 by taking into account cross-time variability. In doing so, we pay careful attention to a comprehensive conceptualisation of living arrangements (including extended and non-family living arrangements. The aim of this paper is to deepen our understanding of family structure and household arrangements in Europe by examining and mapping the cross-national and cross-temporal variety of young adults’ living arrangements. For our analysis we use data from the Integrated Public Use Microdata Series International (IPUMSi for the census rounds 1980, 1990, and 2000 for eight European countries (Austria, France, Greece, Hungary, Ireland, Portugal, Romania, and Switzerland. We employ log-linear models to ascertain the influence of individual and contextual factors on living arrangements. The analyses lend further support to a North/West – South/East divide in living arrangements and general gender differentials in extended family living. Other interesting results are the heterogeneity in the living arrangements of single mothers across geographic areas, and the upward trend of extended household living for young men and women between 1980 and 2000.

  13. Reducing consumption through communal living

    Energy Technology Data Exchange (ETDEWEB)

    Herring, Horace [The Open Univ., Milton Keynes (United Kingdom). Energy and Environment Research Unit

    2003-07-01

    This paper examines ways consumers and communities can voluntarily adopt a low consumption (or low carbon) lifestyle, often termed 'voluntary simplicity' or a policy of 'sufficiency'. There is an increasing academic literature within Europe in the last five years on the whole question of 'sustainable consumption', and the relationship between income levels and consumption particularly at the household. This debate has moved beyond 'green consumerism' to look at building 'new concepts of prosperity' through local community actions, or reducing working time to allow more time for the creation of social capital. The paper will concentrate on one aspect of the quest for sustainable communities, the relevance of communal living to reducing consumption through examining energy consumption (both direct and indirect) in one such community in the UK. The results from this preliminary study reveal that it is not the sharing of resources that reduces consumption but the mutual reinforcement of attitudes towards a low consumption lifestyle. Thus it is the creation of social capital in a community that is its key to its ecological lifestyle.

  14. Tuning SERS for living erythrocytes

    DEFF Research Database (Denmark)

    Brazhe, Nadezda; Parshina, E.Y.; Khabanova, V.V.

    2013-01-01

    Surface-enhanced Raman spectroscopy (SERS) is a unique technique to study submembrane hemoglobin (Hbsm) in erythrocytes. We report the detailed design of SERS experiments on living erythrocytes to estimate dependence of the enhancemen t factor for main Raman bands of Hbsm on silver nanoparticle (Ag......NP) properties. We demonstrate that the enhancement factor for 4/A1g, 10/B1g and A2g Raman bands of Hbsm varies from 105 to 107 under proposed experimental conditions with 473 nm laser excitation. For the first time we show that the enhancement of Raman scattering increases with the increase in the relative...... between small AgNPs and Hbsm and, consequently, leads to the higher enhancement of Raman scattering of Hbsm. The enhancement of higher wavenumber bands 10/B1g and A2g is more sensitive to AgNPs' size and the relative amount of small AgNPs than the enhancement of the lower wavenumber band 4/A1g. This can...

  15. Live broadcast from the Globe

    CERN Multimedia

    La tête au carréTuesday, 17 June 2008 between 2.00 and 3.00 p.m.“La tête au carré”, a France Inter radio programme devoted to science, will set up its sound booth at CERN for a special broadcast on the LHC.The journalist Mathieu Vidard will interview the following guests: - Pierre Van Hove, an experimental physicist working on CMS. He is a CNRS research scientist from the Institut Hubert Curien in Strasbourg, France.- Abdelhak Djouadi is a theoretical physicist. He is a research director at the CNRS’s Laboratoire de physique théorique at Orsay, France and holder of the CNRS silver medal.- Magali Gruwe, one of the engineers in charge of LHC operations at CERN.» To take part in this live broadcast, which is open to the public, come to the Globe at 1:30 p.m. The number of places is limited.» No specialist knowledge required.» See the programme's homepage

  16. [Types of families, living conditions, functioning of family systems and social maladjustment during latency and adolescence in underprivileged milieus].

    Science.gov (United States)

    Le Blanc, M; McDuff, P; Tremblay, R E

    1991-06-01

    Available data on the impact of certain types of families is lacking, and the results are often misleading with respect to maladjustment. Following a description of variations in delinquent activity and behaviour problems according to family type, the authors analyse the difficulties in the operation of family systems. Comparisons of six family types apply to data from 763 boys aged 10, 319 female and 426 male adolescents, aged 14 and 15: intact families, father-based and mother-based single-parent families, father-based and mother-based reconstituted families and substitute families. The article's data show that in the late eighties, nearly 40 per cent of children and adolescents living in low-income districts in Montreal belonged to disunited families. In addition, the data confirm a classic observation: in comparison with intact families, disunited families are underprivileged in relation to living conditions, deficient in relation to psychosocial functioning, and propitious to behaviour problems and delinquent activity. In addition, it has been established that certain disunited family types represent a considerable risk factor. The damaging effect of family structure increases in the following order: intact families, mother-based single-parent families, mother-based reconstituted families, substitute families, father-based reconstituted families and father-based single-parent families. Finally, certain intervention methods are suggested to help prevent behaviour and family problems.

  17. A smart kitchen for ambient assisted living.

    Science.gov (United States)

    Blasco, Rubén; Marco, Álvaro; Casas, Roberto; Cirujano, Diego; Picking, Richard

    2014-01-17

    The kitchen environment is one of the scenarios in the home where users can benefit from Ambient Assisted Living (AAL) applications. Moreover, it is the place where old people suffer from most domestic injuries. This paper presents a novel design, implementation and assessment of a Smart Kitchen which provides Ambient Assisted Living services; a smart environment that increases elderly and disabled people's autonomy in their kitchen-related activities through context and user awareness, appropriate user interaction and artificial intelligence. It is based on a modular architecture which integrates a wide variety of home technology (household appliances, sensors, user interfaces, etc.) and associated communication standards and media (power line, radio frequency, infrared and cabled). Its software architecture is based on the Open Services Gateway initiative (OSGi), which allows building a complex system composed of small modules, each one providing the specific functionalities required, and can be easily scaled to meet our needs. The system has been evaluated by a large number of real users (63) and carers (31) in two living labs in Spain and UK. Results show a large potential of system functionalities combined with good usability and physical, sensory and cognitive accessibility.

  18. A Smart Kitchen for Ambient Assisted Living

    Directory of Open Access Journals (Sweden)

    Rubén Blasco

    2014-01-01

    Full Text Available The kitchen environment is one of the scenarios in the home where users can benefit from Ambient Assisted Living (AAL applications. Moreover, it is the place where old people suffer from most domestic injuries. This paper presents a novel design, implementation and assessment of a Smart Kitchen which provides Ambient Assisted Living services; a smart environment that increases elderly and disabled people’s autonomy in their kitchen-related activities through context and user awareness, appropriate user interaction and artificial intelligence. It is based on a modular architecture which integrates a wide variety of home technology (household appliances, sensors, user interfaces, etc. and associated communication standards and media (power line, radio frequency, infrared and cabled. Its software architecture is based on the Open Services Gateway initiative (OSGi, which allows building a complex system composed of small modules, each one providing the specific functionalities required, and can be easily scaled to meet our needs. The system has been evaluated by a large number of real users (63 and carers (31 in two living labs in Spain and UK. Results show a large potential of system functionalities combined with good usability and physical, sensory and cognitive accessibility.

  19. A Smart Kitchen for Ambient Assisted Living

    Science.gov (United States)

    Blasco, Rubén; Marco, Álvaro; Casas, Roberto; Cirujano, Diego; Picking, Richard

    2014-01-01

    The kitchen environment is one of the scenarios in the home where users can benefit from Ambient Assisted Living (AAL) applications. Moreover, it is the place where old people suffer from most domestic injuries. This paper presents a novel design, implementation and assessment of a Smart Kitchen which provides Ambient Assisted Living services; a smart environment that increases elderly and disabled people's autonomy in their kitchen-related activities through context and user awareness, appropriate user interaction and artificial intelligence. It is based on a modular architecture which integrates a wide variety of home technology (household appliances, sensors, user interfaces, etc.) and associated communication standards and media (power line, radio frequency, infrared and cabled). Its software architecture is based on the Open Services Gateway initiative (OSGi), which allows building a complex system composed of small modules, each one providing the specific functionalities required, and can be easily scaled to meet our needs. The system has been evaluated by a large number of real users (63) and carers (31) in two living labs in Spain and UK. Results show a large potential of system functionalities combined with good usability and physical, sensory and cognitive accessibility. PMID:24445412

  20. Live recombinant BHV/BRSV vaccine

    OpenAIRE

    Keil, G.M.; Rijsewijk, F.A.M.

    1998-01-01

    The present invention refers to synthetic Bovine Respiratory Syncytium virus genes. Also the invention relates to live attenuated Bovine Herpesvirus recombinants carrying such synthetic genes. Furthermore, the invention relates to vaccines based on these live attenuated recombinants, for the protection of cattle against both Bovine herpesvirus infection and against Bovine Respiratory Syncytium virus infection. Also the invention relates to methods for the preparation of such live attenuated r...

  1. Risk measures in living probabilistic safety assessment

    International Nuclear Information System (INIS)

    Holmberg, J.; Niemelae, I.

    1993-05-01

    The main objectives of the study are: to define risk measures and suggested uses of them in various living PSA applications for the operational safety management and to describe specific model features required for living PSA applications. The report is based on three case studies performed within the Nordic research project Safety Evaluation by Use of Living PSA and Safety Indicators. (48 refs., 11 figs., 17 tabs.)

  2. Live-action Virtual Reality Games

    OpenAIRE

    Valente, Luis; Clua, Esteban; Silva, Alexandre Ribeiro; Feijó, Bruno

    2016-01-01

    This paper proposes the concept of "live-action virtual reality games" as a new genre of digital games based on an innovative combination of live-action, mixed-reality, context-awareness, and interaction paradigms that comprise tangible objects, context-aware input devices, and embedded/embodied interactions. Live-action virtual reality games are "live-action games" because a player physically acts out (using his/her real body and senses) his/her "avatar" (his/her virtual representation) in t...

  3. Systema Naturae. Classification of living things.

    OpenAIRE

    Alexey Shipunov

    2007-01-01

    Original classification of living organisms containing four kingdoms (Monera, Protista, Vegetabilia and Animalia), 60 phyla and 254 classes, is presented. The classification is based on latest available information.

  4. Getting to know patients’ lived space

    DEFF Research Database (Denmark)

    Norlyk, Annelise; Martinsen, Bente; Dahlberg, Karen

    2013-01-01

    .g. the role of the good patient and the ambiance of hospitals. Home, on the other hand, offers familiar lived space in which patients feel protected and safe. Further, the paper relates patients’ experience of lived space to a phenomenological view of lived space in order to illustrate the radical influence...... as a theoretical framework for an excursive analysis. The paper demonstrates that existential dimensions of lived space at the hospital and at home differ significantly. For the patients, the hospital space means alien territory as opposed to the familiar territory of home. To some extent the experienced...

  5. Prisoners as Living Donors: A Vulnerabilities Analysis.

    Science.gov (United States)

    Ross, Lainie Friedman; Thistlethwaite, J Richard

    2018-01-01

    Although national guidelines exist for evaluating the eligibility of potential living donors and for procuring their informed consent, no special protections or considerations exist for potential living donors who are incarcerated. Human research subject protections in the United States are codified in the Federal Regulations, 45 CFR 46, and special protections are given to prisoners. Living donor transplantation has parallels with human subject research in that both activities are performed with the primary goal of benefiting third parties. In this article, we describe what special considerations should be provided to prisoners as potential living donors using a vulnerabilities approach adapted from the human research subject protection literature.

  6. A 25 m Live Optics Telescope

    DEFF Research Database (Denmark)

    Ardeberg, Arne; Andersen, Torben; Owner-Petersen, Mette

    1996-01-01

    A 25 m four mirror live optics telescope is studied. M1 is spherical with 141 segments and f/0.96. M1 is reimaged onto M4 also with 141 segments. Image FWHM is 20 arc min. A horseshoe solution with a simple azimuth platform is applied. M1 segments are supported by a fine...... meniscus form truss structure, tied to the horseshoe by a coarser mesh. A FEM with 10^4 dof was developed and applied. Live optics control M1 and M4 segments (the latter with potential high bandwidth). Correction signals in tilt, coma and defocus are traced. A correlation tracker and a lase guide star...... dynamic effects and image quality resulting from the 141 segment spots. Automatic segment control at a bandwidth of only 1 Hz gives excellent image quality. We foresee to reach a bandwidth > 50 Hz, securing a system partly adaptive, with effects of atmospheric wave front tilt removed through M4 segment...

  7. eWall for Active Long Living

    DEFF Research Database (Denmark)

    Mihovska, Albena D.; Kyriazakos, Sofoklis; Prasad, Ramjee

    2014-01-01

    Independent living of senior citizens is one of the main challenges linked to the ageing population, due to the impact on: (1) the life of the elderly people, (2) the national health systems, (3) the insurance companies, (4) the relatives and (5) the care-givers. Senior citizens may suffer from...... a number of diseases, including the decline in cardiopulmonary conditions, weaker muscle functions and a declined neuromuscular control of the movements, which result in a higher risk of fall and a higher vulnerability for cardiovascular and pulmonary diseases. With respect to cognitive functions, senior...... citizens may suffer from a decline of memory function, less ability to orientate and a declined ability to cope with complex situations. This paper describes work in progress and proposes a novel architecture design for eHealth services in support of independent living and compensating for prevailing age...

  8. [Distant mental influence on living organisms].

    Science.gov (United States)

    Bonilla, Ernesto

    2013-12-01

    This article reviews studies of distant mental influence on living organisms, including mental suggestions of sleeping and awakening, mental influence at long distances, mental interactions with remote biological systems, mental effects on physiological activity and the sense of being stared at. Significant effects of distant mental influence have been shown in several randomized controlled trials in humans, animals, plants, bacteria and cells in the laboratory. Although distant mental influence on living organisms appears to contradict our ordinary sense of reality and the laws defined by conventional science, several hypotheses have been proposed to explain the observed effects; they include skeptical, signal transfer, field, multidimensional space/time and quantum mechanics hypotheses. In conclusion, as the progress of physics continues to expand our comprehension of reality, a rational explanation for distant mind-matter interaction will emerge and, as history has shown repeatedly, the supernatural events will evolve into paranormal and then, into normal ones, as the scientific frontiers expand.

  9. 'Smart' homes and telecare for independent living.

    Science.gov (United States)

    Tang, P; Venables, T

    2000-01-01

    Telecare services and 'smart' homes share a common technological base in information technology and telecommunications. There is growing interest in both telecare services and smart homes, although they have been studied in isolation. Telecare has been driven largely by perceived cost savings and improved service delivery to the home, leading to improved quality of life and independent living. Smart homes are also expected to provide better and safer living conditions. The integration of the two should produce more secure and autonomous living. There are different forms of telecare services, as there are different types of smart homes, each ranging from basic systems involving the use of alarms and the ordinary telephone to intelligent monitoring with sensors and interactive communication. The introduction of these systems has policy implications, such as the need for coordination between health, social services and housing policy makers, which will reduce duplication and inefficient allocation of resources. Successful delivery of telecare to the home is as much dependent on the construction and condition of the housing stock as it is on the ability of the care provider to meet users' needs. If the UK National Health Service (NHS) could replace a significant proportion of domiciliary nursing visits by telephone calls, then savings of up of 200 million Pounds per annum would be possible.

  10. 'Living' Architecture Overviews - Supporting the Design of Evolutionary Complex Systems (CD ROM)

    NARCIS (Netherlands)

    Borches Juzgado, P.D.; Bonnema, Gerrit Maarten; van Houten, F.J.A.M.; Miedema, J.; Lutters, D.

    2008-01-01

    When dealing with complex systems, it is essential that designers and system architects have a clear understanding of the system as a whole. The main ‘tool’ for this is the so-called ‘system architecture description’ or ‘reference architecture’. Although the concept of system architecture

  11. Living in a Sustainable World

    International Nuclear Information System (INIS)

    Richards, K. M.

    1998-01-01

    Many would argue that sustainable development is a very simple idea. It is about ensuring a better quality of life for everyone, now and for generations to come. Deeply embedded in the whole concept is the prudent use of natural resources and this very much includes consideration of renewable forms of energy. Historically, in the UK and some other parts of europe the emphasis on development has been towards large scale energy production facilities. This has been seen as a logical progression within an energy industry which has evolved around the centralised, 'big is beautiful' model. Such thinking has lead to renewables being disadvantaged in many ways. Renewables are a disparate resource and often at their peak in rural, isolated and environmentally sensitive areas. Harnessing them may more easily fit with a local community based approach. This airflow's the greater involvement of the local communities themselves, their local Government and industry. It also presents the best opportunity for the protection of the environment and for the change to focus on local agendas. In terms of 'living within a sustainable world' following Kyoto such a community based strategy for the future is more likely to yield success, turning as it must on achieving a fundamental change of attitude within the wider population to energy provision and use. Noteworthy in this respect is the recent White Paper from the European Commission (entitled 'Energy for the Future: Renewable Sources of Energy') which champions the idea of 100 communities in the EU which might be self sufficient in the use of renewable sources of energy. (author)

  12. An On-Line Oxygen Forecasting System for Waterless Live Transportation of Flatfish Based on Feature Clustering

    Directory of Open Access Journals (Sweden)

    Yongjun Zhang

    2017-09-01

    Full Text Available Accurate prediction of forthcoming oxygen concentration during waterless live fish transportation plays a key role in reducing the abnormal occurrence, increasing the survival rate in delivery operations, and optimizing manufacturing costs. The most effective ambient monitoring techniques that are based on the analysis of historical process data when performing forecasting operations do not fully consider current ambient influence. This is likely lead to a greater deviation in on-line oxygen level forecasting in real situations. Therefore, it is not advisable for the system to perform early warning and on-line air adjustment in delivery. In this paper, we propose a hybrid method and its implementation system that combines a gray model (GM (1, 1 with least squares support vector machines (LSSVM that can be used effectively as a forecasting model to perform early warning effectively according to the dynamic changes of oxygen in a closed system. For accurately forecasting of the oxygen level, the fuzzy C-means clustering (FCM algorithm was utilized for classification according to the flatfish’s physical features—i.e., length and weight—for more pertinent training. The performance of the gray model-particle swarm optimization-least squares support vector machines (GM-PSO-LSSVM model was compared with the traditional modeling approaches of GM (1, 1 and LSSVM by applying it to predict on-line oxygen level, and the results showed that its predictions were more accurate than those of the LSSVM and grey model. Therefore, it is a suitable and effective method for abnormal condition forecasting and timely control in the waterless live transportation of flatfish.

  13. Explorer-II: Wireless Self-Powered Visual and NDE Robotic Inspection System for Live Gas Distribution Mains

    Energy Technology Data Exchange (ETDEWEB)

    Carnegie Mellon University

    2008-09-30

    Carnegie Mellon University (CMU) under contract from Department of Energy/National Energy Technology Laboratory (DoE/NETL) and co-funding from the Northeast Gas Association (NGA), has completed the overall system design, field-trial and Magnetic Flux Leakage (MFL) sensor evaluation program for the next-generation Explorer-II (X-II) live gas main Non-destructive Evaluation (NDE) and visual inspection robot platform. The design is based on the Explorer-I prototype which was built and field-tested under a prior (also DoE- and NGA co-funded) program, and served as the validation that self-powered robots under wireless control could access and navigate live natural gas distribution mains. The X-II system design ({approx}8 ft. and 66 lbs.) was heavily based on the X-I design, yet was substantially expanded to allow the addition of NDE sensor systems (while retaining its visual inspection capability), making it a modular system, and expanding its ability to operate at pressures up to 750 psig (high-pressure and unpiggable steel-pipe distribution mains). A new electronics architecture and on-board software kernel were added to again improve system performance. A locating sonde system was integrated to allow for absolute position-referencing during inspection (coupled with external differential GPS) and emergency-locating. The power system was upgraded to utilize lithium-based battery-cells for an increase in mission-time. The resulting robot-train system with CAD renderings of the individual modules. The system architecture now relies on a dual set of end camera-modules to house the 32-bit processors (Single-Board Computer or SBC) as well as the imaging and wireless (off-board) and CAN-based (on-board) communication hardware and software systems (as well as the sonde-coil and -electronics). The drive-module (2 ea.) are still responsible for bracing (and centering) to drive in push/pull fashion the robot train into and through the pipes and obstacles. The steering modules

  14. Living Well with Living Wills: Application of Protection Motivation Theory to Living Wills Among Older Caucasian and African American Adults.

    Science.gov (United States)

    Allen, Rebecca S; Phillips, Laura L; Pekmezi, Dorothy; Crowther, Martha R; Prentice-Dunn, Steven

    2009-01-01

    Using protection motivation theory, we examined racial differences in intent to complete a living will, rational problem solving (e.g., information seeking), and maladaptive coping responses (i.e., wishful thinking) to a health crisis. Sixty healthy, older adults without living wills responded to written vignettes, including information about living wills as an effective coping mechanism to avoid a health crisis. Use of adaptive coping responses predicted intent to execute a living will. A significant race-by-threat interaction predicted use of rational problem solving, with Caucasians more likely to seek information in response to perceived threat in comparison with African Americans. A significant race-by-adaptive-coping interaction predicted maladaptive coping, indicating that Caucasians were more variable in their maladaptive responses. The effectiveness of health care messages regarding living wills for older adults may be enhanced by focusing on racial differences in response to perceived health threat and perceived adaptive coping information.

  15. Transmutation of long-lived fission product (137Cs, 90Sr) by a reactor-accelerator system

    International Nuclear Information System (INIS)

    Toyama, Shin-ichi; Takashita, Hirofumi; Konashi, Kenji; Sasao, Nobuyuki; Sato, Isamu.

    1990-01-01

    The report discusses the transmutation of long-lived fission products by a reactor and accelerator. It is important to take some criteria into consideration in transmutation disposal. To satisfy the criteria, a combined system of a reactor and an accelerator is proposed for the transmutation. An outline of the transmutation reactor and the accelerator is presented. The transmutation reactor has the ability to transmute a large quantity of fission products. However, it is desirable to have a high transmutation rate as well as a large disposal ability. Besides the transmutation property, it is necessary to investigate the physics of the transmutation reactor such as nuclear characteristics and burnup properties in order to obtain the most suitable, high performance core concept. A study on those properties is also presented. A high power accelerator is required for the transmutation. So a test linac is developed to accelerate high intensity beams. (N.K.)

  16. Thermal Management System for Long-Lived Venus Landers, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall program objective is to develop a high-temperature passive thermal management system for the Radioisotope Power Conversion system that energizes the...

  17. Stress-driven pattern formation in living and non-living matter

    DEFF Research Database (Denmark)

    Christensen, Amalie

    . On the smallest scale of nanometers, we study thin films of block copolymers, which have potential applications as self-organizing templates for microelectronics. By performing a thin-shell expansion of a well-known model for block copolymers, we develop an effective model for the impact of curvature on pattern......Spatial pattern formation is abundant in nature and occurs in both living and non-living matter. Familiar examples include sand ripples, river deltas, zebra fur and snail shells. In this thesis, we focus on patterns induced by mechanical stress, and develop continuum theories for three systems...

  18. Sudanese live sheep and mutton exports competitiveness

    Directory of Open Access Journals (Sweden)

    Babiker Idris Babiker

    2011-01-01

    Full Text Available The livestock sector of Sudan provides livelihood for about 17% of the population. Sudanese livestock products meet the domestic demand for meat in addition to a substantial excess for export amounting to about 22% of total country exports. It contributes about 19% of GDP. Sheep marketing in Sudan is characterised by traditional operations and is informally organised, although, recently there are great efforts by the formal livestock authorities to organise some secondary and terminal livestock markets. These markets are deficient in basic infrastructures and systematic marketing research. The system as a whole is faced by various complex obstacles and constraints, which decrease the contribution of livestock in general, and sheep in particular, to the national economy, and suppress the optimum exploitation of this resource. These obstacles are represented in the lack of transportation networks that connect the production and consumption centres to break the seasonality of supply that creates shortages and high prices at the consumption centres. This paper employs the policy analysis matrix (PAM technique to examine the Sudanese live sheep and mutton competitiveness in the international market. The results indicated that the market price was greater than the border price implying a positive incentive as an implicit subsidy to the live sheep exporter. The mutton exporters were found subsidised as well. The international value added (IVA indicted a positive foreign exchange earnings or savings. Exported live sheep and mutton coefficient of competitiveness (CIC implied that sheep and mutton exports are profitable and internationally competitive.

  19. Biomolecular tracing using long-lived isotopes

    International Nuclear Information System (INIS)

    Vogel, J.S.; Turteltaub, K.W.; Frantz, C.E.; Keating, G.; Felton, J.S.; Southon, J.R.; Roberts, M.R.; Gledhill, B.L.

    1992-01-01

    Accelerator mass spectrometry (AMS) was developed over the past 15 years as an essential tool for detecting long-lived, cosmogenic radio-isotopes in the earth and space sciences. We apply this technology to the measurement of chemical kinetics, primarily in biomedical systems, which had heretofore employed short-lived isotopes and/or long counting times to quantify radio-isotopic labels. AMS provides detection efficiencies of ∼ 1%, 10 3 to 10 6 better than decay-counting. Long-lived isotopes are used and detected with AMS at concentrations which reduce sample size, chemical dose, radiation safety hazards and radiolysis. We measure 3 H, 7,1O Be, 14 C, 26 Al, 36 CI, 41 Ca and 129 I, but most of our current program uses 14 C. Initial experiments involved research on the genotoxicity of mutagens in cooked foods and reversible binding of compounds to antibodies. Through collaborations, we apply AMS detection to research in carcinogenesis, pharmacokinetics of toxins, elemental metabolism, distribution of topical medications and nutrition

  20. Features of Microelement Homeostasis in Children Living in the Modern City and Its Effect on the Immune System

    Directory of Open Access Journals (Sweden)

    S.L. Niankovskyi

    2015-10-01

    Full Text Available Introduction. Recently, the issue of environmental pollution with various trace elements becomes increasingly important. Especially their adverse effects, even in small concentrations, on the health of children, in particular the immune system, because the child’s body is more susceptible to their accumulation in the process of the development. Objective. To evaluate the load of micronutrients in children — the inhabi­tants of the modern city of Lviv (Western Ukraine and correlation of immunity parameters with their imbalance. Materials and methods. Using selected randomized copy-pair method, in 50 pairs (n = 100 of healthy children aged 6–15 years who lived in the area of research and rural regions from the birth, we have analyzed the contents of some heavy metals (toxic Pb, Cd and conditionally essential Fe, Cu, Zn, Mn, Co, Cr, Ni in the hair by atomic absorption spectrophotometry. Immune status of children has been assessed in terms of composition and expression of surface phenotypes of immune competent cells by direct immunofluorescence using monoclonal antibody panel. Mathe­matical processing of the findings was carried out by the methods of parametric and nonparametric statistics. Results. The content of heavy metals in children who live in modern cities is exceeded several times. At the same time, there was a reduction of conditionally essential micronutrients. The analysis of correlations between the main indicators of immunogram and concentration of trace elements in biological substrates of children found a close relationship between them, which confirmed the influence of environmental factors on the basic immunological parameters. Mathematical equations also confirmed the presence of factorial-effective relationship in the «environmental pollution — morbidity — micronutrient composition of biosubstrates — immune status» system and have a prognostic significance. Conclusion. Studies have shown that immune status, trace

  1. Active living by design sustainability strategies.

    Science.gov (United States)

    Kraft, M Katherine; Lee, Joanne J; Brennan, Laura K

    2012-11-01

    Despite substantial increases in improving the translation of health promotion research into practice, community initiatives still struggle with maintaining changes once grant funding has ended. Researchers, funders, and community practitioners are interested in practices that maintain and sustain their efforts. This qualitative study conducted a content analysis of evaluation findings from Active Living by Design (ALbD) to identify activities that community coalitions implemented to maintain their initiative and secure ongoing influence in communities. Investigators analyzed data from interviews, focus groups, and the Progress Reporting System to identify sustainability approaches clustering into five areas: partnership expansion, sustainable funding, permanent advisory committees, policy change, and institution/organization change. Partnership expansion occurred across sectors and disciplines and into broader geographic areas. Additional funding extended beyond grants to earned income streams and dedicated tax revenues. Permanent advisory committees were established to inform decision makers about a range of active living impacts. Policy changes in zoning and comprehensive plans ensured maintenance of health-promoting built environments. Sustainability through institution/organization changes led to allocation of dedicated staff and incorporation of active living values into agency missions. Active Living by Design partnerships defined and messaged their projects to align with policymakers' interests and broad partnership audiences. They found innovative supporters and adapted their original vision to include quality of life, nonmotorized transport, and other complementary efforts that expanded their reach and influence. These sustainability strategies altered awareness within communities, changed community decision-making processes, and created policy changes that have the potential to maintain environments that promote physical activity for years to come

  2. [Live style and risk of lifestyle diseases].

    Science.gov (United States)

    Kábrt, Jan

    2014-01-01

    Metabolic syndrome included obesity, diabetes mellitus type II, hypertension and disorder of lipid metabolism are serious complication affecting many people of economic advanced countries. Unhealthy live style with limited physical activity and overfeeding are the main cause of this disorder. Adjustment of the live style with regular physical activity has the better result compared with a diet intervention alone.

  3. Living arrangements of young adults in Europe

    NARCIS (Netherlands)

    Schwanitz, Katrin; Mulder, Clara H.

    2015-01-01

    Comparative research suggests that there are great cross-national and cross-temporal differences in living arrangements of young adults aged 18-34 in Europe. In this paper, we examine young adults’ living arrangements (1) across several European countries and different national contexts, and (2) by

  4. Ordinary Lives Illuminated: Writing Oral History.

    Science.gov (United States)

    Gandesbery, Jean

    1990-01-01

    Describes how writing oral history can help students to feel that they are participating in a lively intellectual and cultural process that travels beyond the limits of the classroom. Says students claim that their obligations to the assignment are surpassed by their feelings of gratification in having created living works with lasting vitality.…

  5. Beauty in the Context of Particular Lives

    Science.gov (United States)

    Rautio, Pauliina

    2010-01-01

    This paper is based on empirical research by the author into the everyday lives of people living in a small village. Everyday life is approached as a subjective process in time and space, experienced by particular people in a particular environmental and social context. The data of this research has been collected through correspondence in which…

  6. Financial considerations in living organ donation.

    Science.gov (United States)

    Jacobs, Cheryl; Thomas, Charlie

    2003-06-01

    The shortage of cadaveric organs and increased success of living donor transplantation support the use of living organ donors. Clinical social workers have the opportunity to explore a variety of donor-specific issues when performing psychosocial evaluations of living donors, including motivation, psychological stability, and personal and family consequences of donation, as well as the direct and indirect financial consequences faced by living donors. Although most donor-related medical costs are covered, other associated expenses are not reimbursable and may put donors at risk for financial hardship. Out-of-pocket expenses also serve as a disincentive to donate for some volunteers. During the evaluation process, healthcare professionals should openly discuss how surgery, recovery, and any potential complications might impact prospective donors' financial situation. Donors can then decide whether they are able to realistically handle the costs of donation. We present the financial dilemmas experienced by many living donors and highlight efforts that have been made to deal with them.

  7. A real-time measurement system for parameters of live biology metabolism process with fiber optics

    Science.gov (United States)

    Tao, Wei; Zhao, Hui; Liu, Zemin; Cheng, Jinke; Cai, Rong

    2010-08-01

    Energy metabolism is one of the basic life activities of cellular in which lactate, O2 and CO2 will be released into the extracellular environment. By monitoring the quantity of these parameters, the mitochondrial performance will be got. A continuous measurement system for the concentration of O2, CO2 and PH value is introduced in this paper. The system is made up of several small-sized fiber optics biosensors corresponding to the container. The setup of the system and the principle of measurement of several parameters are explained. The setup of the fiber PH sensor based on principle of light absorption is also introduced in detail and some experimental results are given. From the results we can see that the system can measure the PH value precisely suitable for cell cultivation. The linear and repeatable accuracies are 3.6% and 6.7% respectively, which can fulfill the measurement task.

  8. Reducing scan angle using adaptive prior knowledge for a limited-angle intrafraction verification (LIVE) system for conformal arc radiotherapy

    Science.gov (United States)

    Zhang, Yawei; Yin, Fang-Fang; Zhang, You; Ren, Lei

    2017-05-01

    The purpose of this study is to develop an adaptive prior knowledge guided image estimation technique to reduce the scan angle needed in the limited-angle intrafraction verification (LIVE) system for 4D-CBCT reconstruction. The LIVE system has been previously developed to reconstruct 4D volumetric images on-the-fly during arc treatment for intrafraction target verification and dose calculation. In this study, we developed an adaptive constrained free-form deformation reconstruction technique in LIVE to further reduce the scanning angle needed to reconstruct the 4D-CBCT images for faster intrafraction verification. This technique uses free form deformation with energy minimization to deform prior images to estimate 4D-CBCT based on kV-MV projections acquired in extremely limited angle (orthogonal 3°) during the treatment. Note that the prior images are adaptively updated using the latest CBCT images reconstructed by LIVE during treatment to utilize the continuity of the respiratory motion. The 4D digital extended-cardiac-torso (XCAT) phantom and a CIRS 008A dynamic thoracic phantom were used to evaluate the effectiveness of this technique. The reconstruction accuracy of the technique was evaluated by calculating both the center-of-mass-shift (COMS) and 3D volume-percentage-difference (VPD) of the tumor in reconstructed images and the true on-board images. The performance of the technique was also assessed with varied breathing signals against scanning angle, lesion size, lesion location, projection sampling interval, and scanning direction. In the XCAT study, using orthogonal-view of 3° kV and portal MV projections, this technique achieved an average tumor COMS/VPD of 0.4  ±  0.1 mm/5.5  ±  2.2%, 0.6  ±  0.3 mm/7.2  ±  2.8%, 0.5  ±  0.2 mm/7.1  ±  2.6%, 0.6  ±  0.2 mm/8.3  ±  2.4%, for baseline drift, amplitude variation, phase shift, and patient breathing signal variation

  9. A web-based non-intrusive ambient system to measure and classify activities of daily living.

    Science.gov (United States)

    Stucki, Reto A; Urwyler, Prabitha; Rampa, Luca; Müri, René; Mosimann, Urs P; Nef, Tobias

    2014-07-21

    The number of older adults in the global population is increasing. This demographic shift leads to an increasing prevalence of age-associated disorders, such as Alzheimer's disease and other types of dementia. With the progression of the disease, the risk for institutional care increases, which contrasts with the desire of most patients to stay in their home environment. Despite doctors' and caregivers' awareness of the patient's cognitive status, they are often uncertain about its consequences on activities of daily living (ADL). To provide effective care, they need to know how patients cope with ADL, in particular, the estimation of risks associated with the cognitive decline. The occurrence, performance, and duration of different ADL are important indicators of functional ability. The patient's ability to cope with these activities is traditionally assessed with questionnaires, which has disadvantages (eg, lack of reliability and sensitivity). Several groups have proposed sensor-based systems to recognize and quantify these activities in the patient's home. Combined with Web technology, these systems can inform caregivers about their patients in real-time (e.g., via smartphone). We hypothesize that a non-intrusive system, which does not use body-mounted sensors, video-based imaging, and microphone recordings would be better suited for use in dementia patients. Since it does not require patient's attention and compliance, such a system might be well accepted by patients. We present a passive, Web-based, non-intrusive, assistive technology system that recognizes and classifies ADL. The components of this novel assistive technology system were wireless sensors distributed in every room of the participant's home and a central computer unit (CCU). The environmental data were acquired for 20 days (per participant) and then stored and processed on the CCU. In consultation with medical experts, eight ADL were classified. In this study, 10 healthy participants (6 women

  10. Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

    Science.gov (United States)

    Rojanathammanee, Lalida; Rakoczy, Sharlene; Brown-Borg, Holly M

    2014-10-01

    Ames dwarf mice are deficient in growth hormone (GH), prolactin, and thyroid-stimulating hormone and live significantly longer than their wild-type (WT) siblings. The lack of GH is associated with stress resistance and increased longevity. However, the mechanism underlying GH's actions on cellular stress defense have yet to be elucidated. In this study, WT or Ames dwarf mice were treated with saline or GH (WT saline, Dwarf saline, and Dwarf GH) two times daily for 7 days. The body and liver weights of Ames dwarf mice were significantly increased after 7 days of GH administration. Mitochondrial protein levels of the glutathione S-transferase (GST) isozymes, K1 and M4 (GSTK1 and GSTM4), were significantly higher in dwarf mice (Dwarf saline) when compared with WT mice (WT saline). GH administration downregulated the expression of GSTK1 proteins in dwarf mice. We further investigated GST activity from liver lysates using different substrates. Substrate-specific GST activity (bromosulfophthalein, dichloronitrobenzene, and 4-hydrox-ynonenal) was significantly reduced in GH-treated dwarf mice. In addition, GH treatment attenuated the activity of thioredoxin and glutaredoxin in liver mitochondria of Ames mice. Importantly, GH treatment suppressed Trx2 and TrxR2 mRNA expression. These data indicate that GH has a role in stress resistance by altering the functional capacity of the GST system through the regulation of specific GST family members in long-living Ames dwarf mice. It also affects the regulation of thioredoxin and glutaredoxin, factors that regulate posttranslational modification of proteins and redox balance, thereby further influencing stress resistance. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. Evaluation of dynamic binaural reproduction system for live transmitted xylophone recording

    DEFF Research Database (Denmark)

    Madsen, Esben; Markovic, Milos; Olesen, Søren Krarup

    2012-01-01

    For a special teaching application of the telepresence research project BEAMING, a scenario of a remote teacher (the Visitor) teaching a local student to play a xylophone through an embodiment is defined. In order to achieve this, a system is required to record, transmit and render the sound....... Finally head tracking allows for a dynamic binaural rendering of the xylophone sound. The goal of this paper is to evaluate the realism of this virtual (auditory) representation of a real xylophone. A listening test is designed to compare characteristics of a real physical xylophone in front...... of the listener with a rendering using the described system. The evaluation is done with a basis in methods previously used for evaluating the subjective sensation of presence in virtual reality systems, mainly based on questionnaires....

  12. In situ Orbit Extraction from Live, High Precision Collisionless Simulations of Systems Formed by Cold Collapse

    Science.gov (United States)

    Noriega-Mendoza, H.; Aguilar, L. A.

    2018-04-01

    We performed high precision, N-body simulations of the cold collapse of initially spherical, collisionless systems using the GYRFALCON code of Dehnen (2000). The collapses produce very prolate spheroidal configurations. After the collapse, the systems are simulated for 85 and 170 half-mass radius dynamical timescales, during which energy conservation is better than 0.005%. We use this period to extract individual particle orbits directly from the simulations. We then use the TAXON code of Carpintero and Aguilar (1998) to classify 1 to 1.5% of the extracted orbits from our final, relaxed configurations: less than 15% are chaotic orbits, 30% are box orbits and 60% are tube orbits (long and short axis). Our goal has been to prove that direct orbit extraction is feasible, and that there is no need to "freeze" the final N-body system configuration to extract a time-independent potential.

  13. Unobtrusive Wireless Monitoring System for Assisted Living and Improving the Wellbeing of Elderly People

    International Nuclear Information System (INIS)

    Browne, Aidan; Duncliffe, Richard; Spillane, James; Walsh, Colin; Hill, Martin; O'Mahony, Tom; O'Reilly, Fergus

    2011-01-01

    A novel system to unobtrusively monitor the wellbeing of elderly people based on their activity patterns is presented. The system uses a wireless ZigBee network to monitor the electrical usage in a subject's home and then sends this data to an Apache server via HTTP from a GPRS unit. The data is logged in a MySQL database where pattern analysis is used to identify periods of significant inactivity. When such an event is identified designated contacts are notified by text message. For subjects requiring higher levels of monitoring a portable health monitor can be integrated incorporating a fall detector and panic button to inform of emergency situations.

  14. Dynamical Properties of a Living Nematic

    Science.gov (United States)

    Genkin, Mikhail

    The systems, which are made of a large number or interacting particles, or agents that convert the energy stored in the environment into mechanical motion, are called active systems, or active matter. The examples of active matter include both living and synthetic systems. The size of agents varies significantly: bird flocks and fish schools represent macroscopic active systems, while suspensions of living organisms or artificial colloidal particles are examples of microscopic ones. In this work, I studied one of the simplest realization of active matter termed living (or active) nematics, that can be conceived by mixing swimming bacteria and nematic liquid crystal. Using modeling, numerical simulations and experiments I studied various dynamical properties of active nematics. This work hints into new methods of control and manipulation of active matter. Active nematic exhibits complex spatiotemporal behavior manifested by formation, proliferation, and annihilation of topological defects. A new computational 2D model coupling nematic liquid crystal and swimming bacteria dynamics have been proposed. We investigated the developed system of partial differential equations analytically and integrated it numerically using the highly efficient parallel GPU code. The integration results are in a very good agreement with other theoretical and experimental studies. In addition, our model revealed a number of testable phenomena. The major model prediction (bacteria accumulation in positive and depletion in negative topological defects) was tested by a dedicated experiment. We extended our model to study active nematics in a biphasic state, where nematic and isotropic phases coexist. Typically this coexistence is manifested by formation of tactoids - isotropic elongated regions surrounded by nematic phase, or nematic regions surrounded by isotropic phase. Using numerical integration, we revealed fundamental properties of such systems. Our main model outcome - spontaneous

  15. Developmental diversity in free-living flatworms

    Directory of Open Access Journals (Sweden)

    Martín-Durán José

    2012-03-01

    Full Text Available Abstract Flatworm embryology has attracted attention since the early beginnings of comparative evolutionary biology. Considered for a long time the most basal bilaterians, the Platyhelminthes (excluding Acoelomorpha are now robustly placed within the Spiralia. Despite having lost their relevance to explain the transition from radially to bilaterally symmetrical animals, the study of flatworm embryology is still of great importance to understand the diversification of bilaterians and of developmental mechanisms. Flatworms are acoelomate organisms generally with a simple centralized nervous system, a blind gut, and lacking a circulatory organ, a skeleton and a respiratory system other than the epidermis. Regeneration and asexual reproduction, based on a totipotent neoblast stem cell system, are broadly present among different groups of flatworms. While some more basally branching groups - such as polyclad flatworms - retain the ancestral quartet spiral cleavage pattern, most flatworms have significantly diverged from this pattern and exhibit unique strategies to specify the common adult body plan. Most free-living flatworms (i.e. Platyhelminthes excluding the parasitic Neodermata are directly developing, whereas in polyclads, also indirect developers with an intermediate free-living larval stage and subsequent metamorphosis are found. A comparative study of developmental diversity may help understanding major questions in evolutionary biology, such as the evolution of cleavage patterns, gastrulation and axial specification, the evolution of larval types, and the diversification and specialization of organ systems. In this review, we present a thorough overview of the embryonic development of the different groups of free-living (turbellarian platyhelminths, including the Catenulida, Macrostomorpha, Polycladida, Lecithoepitheliata, Proseriata, Bothrioplanida, Rhabdocoela, Fecampiida, Prolecithophora and Tricladida, and discuss their main features

  16. Motivate: towards context-aware recommendation mobile system for healthy living

    NARCIS (Netherlands)

    Lin, Y.; Jessurun, J.; Vries, de B.; Timmermans, H.J.P.

    2011-01-01

    This paper presents the practices of a research aiming at the design of a context-aware recommendation system that promotes the adoption of a healthy and active lifestyle. A Smartphone application that provides personalized and contextualized advice on physical activities was developed. The goal of

  17. Community Living Skills Guide: Additional Activities for Nutrition, Cooking, Homemaking, and Family Living.

    Science.gov (United States)

    Nickovich, Marti; Kreps, Alice Roelofs

    These activities are intended to supplement materials for three courses available in the Community Living Skills Guide for the College for Living series: Cooking/Food Preparation (CE 024 475), Homemaking and Family Living (CE 024 477), and Nutrition (CE 024 484). These courses for developmentally disabled adults are intended to supplement…

  18. Solar Living House Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Walters, Bradley [Univ. of Florida, Gainesville, FL (United States)

    2017-03-09

    The Solar Living House is a high-performance solar-powered dwelling designed by a team of faculty and students from the University of Florida, in collaboration with Santa Fe College, the National University of Singapore, and Alachua Habitat for Humanity. The project was designed in accordance with the Solar Decathlon 2015, a research, design, education, and outreach program developed by the U.S. Department of Energy (DOE). The Solar Living House is fundamentally a house for living, centered on people and the activities of daily life while quietly introducing advanced design, construction, and engineering technologies. The 993 square-foot two-bedroom one-bath home was designed to embrace and frame an exterior courtyard space. This courtyard acts as an extension of the interior living spaces, maximizing the spatial potentials of a modest building footprint and introducing natural light into the primary living spaces of the house. Research Outcomes: The Solar Living House advances work on high-performance buildings through three principal technological innovations: wet/dry modular construction, a building automation system, and solar dehumidification systems. Wet / Dry Modular Construction: The house is designed as a series of five modules, including one that is designated as the “wet core.” The wet core consolidates the mechanical systems and bathroom into a single module to reduce plumbing runs, efficiency losses, and on-site construction time. The other four modules are designed to eliminate interior load bearing walls to allow for maximum flexibility in the reconfiguring of the space over time. The modules are designed to meet the structural challenges of both Florida’s hurricanes and California’s earthquakes. Building Automation System: The house is equipped with an integrated building automation system, allowing the houses environmental systems, lights, security systems, and smoke detectors to be programmed, monitored, and controlled through any mobile

  19. The everyday lives of video game developers: Experimentally understanding underlying systems/structures

    Directory of Open Access Journals (Sweden)

    Casey O'Donnell

    2009-03-01

    Full Text Available This essay examines how tensions between work and play for video game developers shape the worlds they create. The worlds of game developers, whose daily activity is linked to larger systems of experimentation and technoscientific practice, provide insights that transcend video game development work. The essay draws on ethnographic material from over 3 years of fieldwork with video game developers in the United States and India. It develops the notion of creative collaborative practice based on work in the fields of science and technology studies, game studies, and media studies. The importance of, the desire for, or the drive to understand underlying systems and structures has become fundamental to creative collaborative practice. I argue that the daily activity of game development embodies skills fundamental to creative collaborative practice and that these capabilities represent fundamental aspects of critical thought. Simultaneously, numerous interests have begun to intervene in ways that endanger these foundations of creative collaborative practice.

  20. Living in The Matrix: Virtual Reality Systems and Hyperspatial Representation in Architecture

    OpenAIRE

    Kacmaz Erk, Gul

    2016-01-01

    In the digital age, the hyperspace of virtual reality systems stands out as a new spatial concept creating a parallel realm to "real" space. Virtual reality influences one’s experience of and interaction with architectural space. This "otherworld" brings up the criticism of the existing conception of space, time and body. Hyperspaces are relatively new to designers but not to filmmakers. Their cinematic representations help the comprehension of the outcomes of these new spaces. Visualisation ...

  1. Living benthic Foraminifera from the Saquarema lagoonal system (Rio de Janeiro, southeastern Brazil)

    OpenAIRE

    Belart, Pierre; Laut, Vanessa; Clemente, Iara; Raposo, Débora; Martins, Virgínia; Frontalini, Fabrizio; Lorini, Maria; Fortes, Rafael; Laut, Lazaro

    2017-01-01

    Transitional environments such as coastal lagoons with narrow connections to the sea are ecosystems very sensitive to natural or anthropogenic pressures. They are biodiversity hotspots and for this reason it should be studied and preserved. This study lists the benthic Foraminifera species from the Saquarema lagoonal system (SLS), Rio de Janeiro state, Brazil. This complex ecosystem consists of four large connected lagoons, namely Urussanga, Jardim, Boqueirão, and Saquarema. A poorly diversif...

  2. Living PRAs [probabilistic risk analysis] made easier with IRRAS [Integrated Reliability and Risk Analysis System

    International Nuclear Information System (INIS)

    Russell, K.D.; Sattison, M.B.; Rasmuson, D.M.

    1989-01-01

    The Integrated Reliability and Risk Analysis System (IRRAS) is an integrated PRA software tool that gives the user the ability to create and analyze fault trees and accident sequences using an IBM-compatible microcomputer. This program provides functions that range from graphical fault tree and event tree construction to cut set generation and quantification. IRRAS contains all the capabilities and functions required to create, modify, reduce, and analyze event tree and fault tree models used in the analysis of complex systems and processes. IRRAS uses advanced graphic and analytical techniques to achieve the greatest possible realization of the potential of the microcomputer. When the needs of the user exceed this potential, IRRAS can call upon the power of the mainframe computer. The role of the Idaho National Engineering Laboratory if the IRRAS program is that of software developer and interface to the user community. Version 1.0 of the IRRAS program was released in February 1987 to prove the concept of performing this kind of analysis on microcomputers. This version contained many of the basic features needed for fault tree analysis and was received very well by the PRA community. Since the release of Version 1.0, many user comments and enhancements have been incorporated into the program providing a much more powerful and user-friendly system. This version is designated ''IRRAS 2.0''. Version 3.0 will contain all of the features required for efficient event tree and fault tree construction and analysis. 5 refs., 26 figs

  3. Top-down models in biology: explanation and control of complex living systems above the molecular level.

    Science.gov (United States)

    Pezzulo, Giovanni; Levin, Michael

    2016-11-01

    It is widely assumed in developmental biology and bioengineering that optimal understanding and control of complex living systems follows from models of molecular events. The success of reductionism has overshadowed attempts at top-down models and control policies in biological systems. However, other fields, including physics, engineering and neuroscience, have successfully used the explanations and models at higher levels of organization, including least-action principles in physics and control-theoretic models in computational neuroscience. Exploiting the dynamic regulation of pattern formation in embryogenesis and regeneration requires new approaches to understand how cells cooperate towards large-scale anatomical goal states. Here, we argue that top-down models of pattern homeostasis serve as proof of principle for extending the current paradigm beyond emergence and molecule-level rules. We define top-down control in a biological context, discuss the examples of how cognitive neuroscience and physics exploit these strategies, and illustrate areas in which they may offer significant advantages as complements to the mainstream paradigm. By targeting system controls at multiple levels of organization and demystifying goal-directed (cybernetic) processes, top-down strategies represent a roadmap for using the deep insights of other fields for transformative advances in regenerative medicine and systems bioengineering. © 2016 The Author(s).

  4. Attempts to identify a control system for chemical reactivity in the living state using virtual energy.

    Science.gov (United States)

    Reid, B L; Bourke, C

    2001-07-01

    This thesis explores the activation of chemicals in metabolic systems from the viewpoint that this activation is under the control of elements of the space-sea in which the chemicals are immersed. Themselves inert, the chemicals are theorised to exploit a force or action issuing from space (fluctuation) and characterized by the homogeneity (termed symmetry) of this medium. The fluctuation is heterogenized upon collision with matter from the intervention of well recognized fields of gravity and electromagnetism at the instant of its issue to form the near field of radiation. Fractions of original space waves and of their intrinsic spin are produced resulting in the activation of the orbitals (valency) in the chemical itself. The thesis continues: the disturbed fluctuation must return to space, obliging in turn, a prior return to the homogeneous state requiring special restorative wave rearrangements known as resonance. The success of the restorative resonance is signalled by a singularity of the fluctuation now propelled to infinity (space), and the contingent chemical reactions thereby terminated. Compromise to this return can occur from many causes and, in its presence, activation of the orbitals continues. They now effectively constitute autonomous reactions alienated from the system as a whole. The thesis is supported from evidence from diverse fields such as space theory, history of quantum field theory in attempts to derive its meaning, dielectrics and the near field of electromagnetic radiation, electron-space interactions at the Fermi surface during phase transitions and evolution of equilibrium conditions in resonance phenomena. The utility of the hypothesis rests on recognition of the resonance condition at various points in the system sufficiently macroscopic as to be available clinically as an abrupt interface between physiology and pathology. Copyright 2001 Harcourt Publishers Ltd.

  5. Meiobenthos assemblages in the mekong estuarine system with special focus on free-living marine nematodes

    Science.gov (United States)

    Quang, Ngo Xuan; Vanreusel, Ann; Smol, Nic; Chau, Nguyen Ngoc

    2010-12-01

    Meiobenthos assemblages in eight estuaries of the Mekong river system were investigated in August 2008 (from the Cua Tieu estuary to the Tran De estuary). In each estuary, one sampling station was established for meiobenthos sampling. Twelve major taxa of meiobenthos were recorded in this estuarine system, including Nematoda, Copepoda, Turbellaria, Polychaeta, Oligochaeta, Tardigrada, Bivalvia, Ostracoda, Amphipoda, Cumacea, Gastrotricha, Gastropoda, and Crustacean Nauplii larvae. The densities of the meiobenthos range from 581 to 3168 inds/10 cm2. Nematodes always occupy the highest numbers with a percentage ranging from 64-99%. There are 135 nematode genera recorded in this study with the following as dominant genera Desmodora, Leptolaimus, Halalaimus, Thalassomonhystera, Theristus, Daptonema, Rhynchonema, Parodontophora, and Oncholaimus. Although the biodiversity of the meiobenthos at higher taxa level is not high compared to other marine environments, the estimates of nematode biodiversity at the genus level indicates high values. The increase in number of genera with increasing sampling intensity illustrate that the diversity is underestimated and would have been higher if the authors had considered a larger number of individuals, more replicates per station, and more sampling stations.

  6. Development of the living thing transportation systems worksheet on learning cycle model to increase student understanding

    Science.gov (United States)

    Rachmawati, E.; Nurohman, S.; Widowati, A.

    2018-01-01

    This study aims to know: 1) the feasibility LKPD review of aspects of the didactic requirements, construction requirements, technical requirements and compliance with the Learning Cycle. 2) Increase understanding of learners with Learning Model Learning Cycle in SMP N 1 Wates in the form LKPD. 3) The response of learners and educators SMP N 1 Wates to quality LKPD Transportation Systems Beings. This study is an R & D with the 4D model (Define, Design, Develop and Disseminate). Data were analyzed using qualitative analysis and quantitative analysis. Qualitative analysis in the form of advice description and assessment scores from all validates that was converted to a scale of 4. While the analysis of quantitative data by calculating the percentage of materializing learning and achievement using the standard gain an increased understanding and calculation of the KKM completeness evaluation value as an indicator of the achievement of students understanding. the results of this study yield LKPD IPA model learning Cycle theme Transportation Systems Beings obtain 108.5 total scores of a maximum score of 128 including the excellent category (A). LKPD IPA developed able to demonstrate an improved understanding of learners and the response of learners was very good to this quality LKPD IPA.

  7. A Phoswich Detector System to Measure Sub-Second Half-Lives using ICF Reactions

    Science.gov (United States)

    Coats, Micah; Cook, Katelyn; Yuly, Mark; Padalino, Stephen; Sangster, Craig; Regan, Sean

    2017-10-01

    The 3H(t,γ)6He cross section has not been measured at any bombarding energy due to the difficulties of simultaneously producing both a tritium beam and target at accelerator labs. An alternative technique may be to use an ICF tt implosion at the OMEGA Laser Facility. The 3H(t,γ)6He cross section could be determined in situ by measuring the beta decay of 6He beginning a few milliseconds after the shot along with other ICF diagnostics. A dE-E phoswich system capable of surviving in the OMEGA target chamber was tested using the SUNY Geneseo pelletron to create neutrons via 2H(d,n)3He and subsequently 6He via 9Be(n,α)6He in a beryllium target. The phoswich dE-E detector system was used to select beta decay events and measure the 807 ms half-life of 6He. It is composed of a thin, 2 ns decay time dE scintillator optically coupled to a thick, 285 ns E scintillator, with a linear gate to separate the short dE pulse from the longer E tail. Funded in part by a Grant from the DOE through the Laboratory for Laser Energetics.

  8. Activity recognition based on inertial sensors for ambient assisted living

    NARCIS (Netherlands)

    Davis, K.; Owusu, E.; Bastani, V.; Marcenaro, L.; Hu, J.; Regazzoni, C.; Feijs, L.M.G.

    2016-01-01

    Ambient Assisted Living (AAL) aims to create innovative technical solutions and services to support independent living among older adults, improve their quality of life and reduce the costs associated with health and social care. AAL systems provide health monitoring through sensor based

  9. Telemonitoring for assisted living residences: the medical specialists' view.

    NARCIS (Netherlands)

    Alizadeh, S.; Bakkes, S.C.J.; Kanis, M.; Rijken, M.; Kröse, B.J.A.; Jordanova, M.; Lievens, F.

    2011-01-01

    Telemonitoring is regarded as a means to maintain a relatively high quality of life for independently living elderly. This paper discusses a requirements study of a system to, foremost, telemonitor activities of daily living (ADL) of the elderly. The study utilizes literature and in-depth interviews

  10. Community Living and the Denormalization of the Family.

    Science.gov (United States)

    Pivato, Emma

    1986-01-01

    A parent of a severely handicapped daughter living at home in Alberta, Canada, discusses the need for family support systems such as respite care, reduced rent for needed equipment or vehicles, and financial aid to allow normal family living. Government and family are seen to share responsibility for the handicapped individual. (DB)

  11. Lab-On-Chip Clinorotation System for Live-Cell Microscopy Under Simulated Microgravity

    Science.gov (United States)

    Yew, Alvin G.; Atencia, Javier; Chinn, Ben; Hsieh, Adam H.

    2013-01-01

    Cells in microgravity are subject to mechanical unloading and changes to the surrounding chemical environment. How these factors jointly influence cellular function is not well understood. We can investigate their role using ground-based analogues to spaceflight, where mechanical unloading is simulated through the time-averaged nullification of gravity. The prevailing method for cellular microgravity simulation is to use fluid-filled containers called clinostats. However, conventional clinostats are not designed for temporally tracking cell response, nor are they able to establish dynamic fluid environments. To address these needs, we developed a Clinorotation Time-lapse Microscopy (CTM) system that accommodates lab-on- chip cell culture devices for visualizing time-dependent alterations to cellular behavior. For the purpose of demonstrating CTM, we present preliminary results showing time-dependent differences in cell area between human mesenchymal stem cells (hMSCs) under modeled microgravity and normal gravity.

  12. Variation in levels of anxiety to dental treatment among nonorphan and orphan children living under different systems.

    Science.gov (United States)

    Chikkala, Jayanth; Chandrabhatla, Srinivas Kumar; Vanga, Narasimha Rao V

    2015-08-01

    It is essential to understand the factors influencing the level of anxiety to dental treatment among different children as it can influence seeking dental care. Here, we assessed the impact of parental loss on dental anxiety among 6-13-year-old children. A total of 444 children within the age group 6-13 years were selected. Group 1 consisted of orphan children living in government-run orphanages, Group 2 consisted of orphan children taken care by a person with a motherly relationship, Group 3 consisted of abandoned children living in private organization and Group 4 consisted of children living with their parents. Dental anxiety was measured using children's fear survey schedule-dental subscale and modified faces version of modified child dental anxiety scale. The highest number of anxious children were observed in Group 4 and the difference in the anxiety levels among the four groups was found to be highly statistically significant. Children living in government-run orphanages had least dental anxiety. All the orphans may not have the same anxiety levels and the environment of upbringing the orphans plays a significant role in the development of the anxiety.

  13. Customized Computer Vision and Sensor System for Colony Recognition and Live Bacteria Counting in Agriculture

    Directory of Open Access Journals (Sweden)

    Gabriel M. ALVES

    2016-06-01

    Full Text Available This paper presents an arrangement based on a dedicated computer and charge-coupled device (CCD sensor system to intelligently allow the counting and recognition of colony formation. Microbes in agricultural environments are important catalysts of global carbon and nitrogen cycles, including the production and consumption of greenhouse gases in soil. Some microbes produce greenhouse gases such as carbon dioxide and nitrous oxide while decomposing organic matter in soil. Others consume methane from the atmosphere, helping to mitigate climate change. The magnitude of each of these processes is influenced by human activities and impacts the warming potential of Earth’s atmosphere. In this context, bacterial colony counting is important and requires sophisticated analysis methods. The method implemented in this study uses digital image processing techniques, including the Hough Transform for circular objects. The visual environment Borland Builder C++ was used for development, and a model for decision making was incorporated to aggregate intelligence. For calibration of the method a prepared illuminated chamber was used to enable analyses of the bacteria Escherichia coli, and Acidithiobacillus ferrooxidans. For validation, a set of comparisons were established between this smart method and the expert analyses. The results show the potential of this method for laboratory applications that involve the quantification and pattern recognition of bacterial colonies in solid culture environments.

  14. An Integrated GIS-Expert System Framework for Live Hazard Monitoring and Detection

    Directory of Open Access Journals (Sweden)

    Steven M. Rozic

    2008-02-01

    Full Text Available In the context of hazard monitoring, using sensor web technology to monitor anddetect hazardous conditions in near-real-time can result in large amounts of spatial data thatcan be used to drive analysis at an instrumented site. These data can be used for decisionmaking and problem solving, however as with any analysis problem the success ofanalyzing hazard potential is governed by many factors such as: the quality of the sensordata used as input; the meaning that can be derived from those data; the reliability of themodel used to describe the problem; the strength of the analysis methods; and the ability toeffectively communicate the end results of the analysis. For decision makers to make use ofsensor web data these issues must be dealt with to some degree. The work described in thispaper addresses all of these areas by showing how raw sensor data can be automaticallytransformed into a representation which matches a predefined model of the problem context.This model can be understood by analysis software that leverages rule-based logic andinference techniques to reason with, and draw conclusions about, spatial data. These toolsare integrated with a well known Geographic Information System (GIS and existinggeospatial and sensor web infrastructure standards, providing expert users with the toolsneeded to thoroughly explore a problem site and investigate hazards in any domain.

  15. TAX SYSTEM FOR MEMBERS OF THE PERSONNEL LIVING IN FRANCE - DECLARATION OF INCOME FOR 2003 -

    CERN Document Server

    HR Department

    2004-01-01

    (Please see the web pages) Important The French tax authorities have informed the Organization of certain changes to the tax system applicable to certain members of the CERN personnel residing in France. The CERN Management is currently seeking to clarify a number of points relating to the application of these measures. For the moment, members of the personnel residing in France are requested to follow the instructions(1) outlined below and any other related instructions published later in 2004. To deal with the increasing number of requests for personal advice, the Human Resources Department has set up a Help-Desk, on 72838, which will direct you to the relevant in-house or outside services. However, as the Human Resources Department cannot speak for the tax authorities and does not have the necessary resources to handle all the problems that are referred to it, members of the personnel are strongly urged to contact the French tax authorities directly, either at the information desks organised at the pla...

  16. TAX SYSTEM FOR MEMBERS OF THE PERSONNEL LIVING IN FRANCE -DECLARATION OF INCOME FOR 1999-

    CERN Document Server

    Division des ressources humaines

    2000-01-01

    This text is also available on the Human Resources Division Web site.ImportantThe French tax authorities have informed the Organisation of certain changes to the tax system applicable to certain members of the CERN personnel residing in France. The CERN Management is currently seeking to clarify a number of points relating to the application of these measures. For the moment, members of the personnel residing in France are requested to follow the intructions outlined below and any other related instructions published later in 2000.To deal with the increasing number of requests for personal advice, the Human Resources Division has set up a Help-Desk, on 72838, which will direct you to the relevant in-house or outside services.However, as the Human Resources Division cannot speak for the tax authorities and does not have the necessary resources to handle all the problems that are referred to it, members of the personnel are strongly urged to contact the French tax authorities directly, either at the information...

  17. 7th Ambient Assisted Living Congress

    CERN Document Server

    Klausing, Helmut

    2015-01-01

    In this book, leading authors in the field discuss developments of Ambient Assisted Living. The contributions have been chosen and invited at the 7th AAL congress, Berlin. It presents new technological developments which support the autonomy and independence of individuals with special needs. As the technological innovation raises also social issues, the book addresses micro and macro economical aspects of assistive systems and puts an additional emphasis on the ethical and legal discussion. The presentation is supported by real world examples and applications.

  18. Genetic analysis of eight population groups living in Taiwan using a 13 X-chromosomal STR loci multiplex system.

    Science.gov (United States)

    Hwa, Hsiao-Lin; Lee, James Chun-I; Chang, Yih-Yuan; Yin, Hsiang-Yi; Chen, Ya-Hui; Tseng, Li-Hui; Su, Yi-Ning; Ko, Tsang-Ming

    2011-01-01

    A 13 X-chromosomal short tandem repeat (STR) multiplex system (DXS6807, DXS8378, DSX9902, DXS7132, DXS9898, DXS6809, DXS6789, DXS7424, DXS101, GATA172D05, HPRTB, DXS8377, and DXS7423) was tested on 1,037 DNA samples from eight population groups currently living in Taiwan. Different distributions of the allelic frequencies in different populations were presented. DXS8377 and DXS101 were the two most polymorphic loci in these eight populations, whereas DXS7423 was the least informative marker in most of the populations studied. The genetic distances between the populations and the constructed phylogenetic tree revealed a long genetic distance between Asian and Caucasian populations as well as isolation of the Tao population. The phylogenetic tree grouped populations into clusters compatible with their ethnogeographic relationships. This 13 X-chromosomal short tandem repeat multiplex system offers a considerable number of polymorphic patterns in different populations. This system can be useful in forensic identification casework and ethnogeographic research.

  19. Designing Viable Business Models for Living Labs

    Directory of Open Access Journals (Sweden)

    Bernhard R. Katzy

    2012-09-01

    Full Text Available Over 300 regions have integrated the concept of living labs into their economic development strategy since 2006, when the former Finnish Prime Minister Esko Aho launched the living lab innovation policy initiative during his term of European presidency. Despite motivating initial results, however, success cases of turning research into usable new products and services remain few and uncertainty remains on what living labs actually do and contribute. This practitioner-oriented article presents a business excellence model that shows processes of idea creation and team mobilization, new product development, user involvement, and entrepreneurship through which living labs deliver high-potential investment opportunities. Customers of living labs are identified as investors such as venture capitalists or industrial firms because living labs can generate revenue from them to create their own sustainable business model. The article concludes that living labs provide extensive support “lab” infrastructure and that it remains a formidable challenge to finance it, which calls for a more intensive debate.

  20. State of living PSA and further development

    International Nuclear Information System (INIS)

    1999-01-01

    In October 1985 OECD-Principal Working Group (PWG 5) - Risk Assessment has initiated the Task Force 7 'Use of PSA in Nuclear Power Plant Management' to explore and report on the principles, characteristics, requirements and status of PSA oriented safety management. During this study, it became apparent that the utilisation of PSA techniques in nuclear plant safety management requires the development of supporting programmes to ensure that PSA models are being updated to reflect plant changes, and to direct their use towards the evaluation and determination of plant changes. These requirements also influence the software and hardware characteristics necessary to support the programme. This overall process is known as Living PSA. In this context OECD-PWG 5 has arranged international workshops on Living PSA application to support this development, to facilitate exchange of international experience and to summarise the state-of-the-art of L-PSA methodology. These activities were accompanied by following Task Groups of OECD-PWG 5 and the work results were published in state-of-the-art reports. According to the increasing development of Living PSA in the international field and its capacity to support plant safety management in a broad sense, OECD PWG 5 continues its work in setting up the Task Group 96-1 'State of Living PSA and Further Development' to clarify specific aspects of Living PSA. This report summarises the state of Living PSA in the international field based on the four Living PSA Workshops from 1988 to 1994 (Chapter 2) and the state of Reliability Data Collection based on the results of Task Group 12 'Reliability Data Collection and Analysis to Support PSA' and the two Data-Workshops from 1995 and 1998 (Chapter 3). The specific items of further development of Living PSA application as mentioned above are treated in Chapter 4. Chapter 5 gives a summary of the current state of Living PSA as well as outlook and recommendations of further development

  1. Progression to surgery: online versus live seminar.

    Science.gov (United States)

    Miletics, Maureen; Claros, Leonardo; Stoltzfus, Jill; Davis, Terri; Chaar, Maher El

    2018-03-01

    The objective of this study was to evaluate progression to surgery rates for live and online seminar and assess weight loss outcome comparisons at 1-year postoperation. University Hospital Network, Allentown, PA, USA. The entry point into our program was an information seminar where prospective patients are educated about obesity, bariatric surgery, indications and contraindications, risks and benefits, and our center's process. Between January of 2009 and November of 2011, only live information seminars were offered. In November of 2011, we started offering an online information seminar to reach those who are unable to attend a live seminar. Tracking of live versus online seminar attendance was documented in our database. Between November 1, 2011 and September 30, 2015, 3484 people completed an information seminar. Of those, 2744 attendees came to a live seminar while 740 completed the online seminar. A significantly higher number of live seminar attendees, 78.1% (2144/2744) progressed to an office visit compared with online seminar attendees 66.5% (492/740), Ponline attendees (Ponline seminar, P = .65) and initial body mass index (46.3 ± 7.4 for live seminar versus 45.3 ± 7.1 for online seminar, P = .09) were very similar between the groups. Online seminar attendees' age (42.7 ± 12.1) was younger than that of the live seminar attendees' (47.3 ± 12.3) (P<.0001) but has little clinical value. Our results demonstrated that live seminar attendees are more likely to progress to surgery and therefore should continue to be offered. Copyright © 2018 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  2. 182Hf-182W age dating of a 26Al-poor inclusion and implications for the origin of short-lived radioisotopes in the early Solar System

    DEFF Research Database (Denmark)

    Holst, Jesper Christian; Olsen, Mia Bjørg Stolberg; Paton, Chad

    2013-01-01

    provide a unique window into the earliest Solar System, including the origin of short-lived radioisotopes. However, their chronology is unknown. Using the 182Hf–182W chronometer, we show that a FUN CAI recording a condensation origin from a solar gas formed coevally with canonical CAIs, but with 26Al/27Al......Refractory inclusions [calcium–aluminum-rich inclusions, (CAIs)] represent the oldest Solar System solids and provide information regarding the formation of the Sun and its protoplanetary disk. CAIs contain evidence of now extinct short-lived radioisotopes (e.g., 26Al, 41Ca, and 182Hf) synthesized...... in one or multiple stars and added to the protosolar molecular cloud before or during its collapse. Understanding how and when short-lived radioisotopes were added to the Solar System is necessary to assess their validity as chronometers and constrain the birthplace of the Sun. Whereas most CAIs formed...

  3. Reaction of long-lived radicals and vitamin C in γ-irradiated mammalian cells and their model system at 295 K. Tunneling reaction in biological system

    International Nuclear Information System (INIS)

    Matsumoto, Takuro; Miyazaki, Tetsuo; Kosugi, Yoshio; Kumada, Takayuki; Koyama, Sinji; Kodama, Seiji; Watanabe, Masami.

    1996-01-01

    When golden hamster embryo (GHE) cells or concentrated albumin solution (0.1 kg dm -3 ) that is a model system of cells is irradiated with γ-rays at 295 K, organic radicals produced can be observed by ESR. The organic radicals survive at both 295 K and 310 K for such a long time as 20 hr. The long-lived radicals in GHE cells and the albumin solution react with vitamin C by the rate constants of 0.007 dm 3 mol -1 s -1 and 0.014 dm 3 mol -1 s -1 , respectively. The long-lived radicals in human cells cause gene mutation, which is suppressed by addition of vitamin C. The isotope effect on the rate constant (k) for the reaction of the long-lived radicals and vitamin C has been studied in the albumin solution by use of protonated vitamin C and deuterated vitamin C. The isotope effect (k H /k D ) was more than 20-50 and was interpreted in terms of tunneling reaction. When GHE cells or the aqueous albumin solution (0.1 kg dm -3 ) is irradiated with γ-rays at 295 K, organic radicals produced survive for more than 24 hr at room temperature. Very recently we have found that vitamin C reacts with the long-lived organic radicals in the γ-irradiated albumin solution at high concentration of 0.1 kg dm -3 by the rate constant of 0.014 dm 3 mol -1 s -1 . Since most of reactions in biological systems including the reaction of vitamin C are a transfer of a hydrogen atom or a proton that has a large wave character, it is generally expected that the tunneling reaction may play an important role in biological systems at room temperature. The studies of isotope effects on reactions will give an information on the contribution of tunneling reaction. (J.P.N.)

  4. Who's in the business of saving lives?

    Science.gov (United States)

    Lee Chang, Pepe

    2006-10-01

    There are individuals, including children, dying needlessly in poverty-stricken third world countries. Many of these deaths could be prevented if pharmaceutical companies provided the drugs needed to save their lives. Some believe that because pharmaceutical companies have the power to save lives, and because they can do so with little effort, they have a special obligation. I argue that there is no distinction, with respect to obligations and responsibilities, between pharmaceutical companies and other types of companies. As a result, to hold pharmaceutical companies especially responsible for saving lives in third world countries is unjustified.

  5. Biomimetic silica encapsultation of living cells

    Science.gov (United States)

    Jaroch, David Benjamin

    Living cells perform complex chemical processes on size and time scales that artificial systems cannot match. Cells respond dynamically to their environment, acting as biological sensors, factories, and drug delivery devices. To facilitate the use of living systems in engineered constructs, we have developed several new approaches to create stable protective microenvironments by forming bioinspired cell-membrane-specific silica-based encapsulants. These include vapor phase deposition of silica gels, use of endogenous membrane proteins and polysaccharides as a site for silica nucleation and polycondensation in a saturated environment, and protein templated ordered silica shell formation. We demonstrate silica layer formation at the surface of pluripotent stem-like cells, bacterial biofilms, and primary murine and human pancreatic islets. Materials are characterized by AFM, SEM and EDS. Viability assays confirm cell survival, and metabolite flux measurements demonstrate normal function and no major diffusion limitations. Real time PCR mRNA analysis indicates encapsulated islets express normal levels of genetic markers for β-cells and insulin production. The silica glass encapsulant produces a secondary bone like calcium phosphate mineral layer upon exposure to media. Such bioactive materials can improve device integration with surrounding tissue upon implantation. Given the favorable insulin response, bioactivity, and long-term viability observed in silica-coated islets, we are currently testing the encapsulant's ability to prevent immune system recognition of foreign transplants for the treatment of diabetes. Such hybrid silica-cellular constructs have a wide range of industrial, environmental, and medical applications.

  6. MEART: the semi-living artist

    Directory of Open Access Journals (Sweden)

    Douglas J Bakkum

    2007-11-01

    Full Text Available Here, we and others describe an unusual neurorobotic project, a merging of art and science called MEART, the semi-living artist.We built a pneumatically actuated robotic arm to create drawings, as controlled by a living network of neurons from rat cortex grown on a multielectrode array (MEA. Such embodied cultured networks formed a real-time closed-loop system which could now behave and receive electrical stimulation as feedback on its behavior.We used MEART and simulated embodiments, or animats, to study the network mechanisms that produce adaptive, goal-directed behavior. This approach to neural interfacing will help instruct the design of other hybrid neuralrobotic systems we call hybrots. The interfacing technologies and algorithms developed have potential applications in responsive deep brain stimulation systems and for motor prosthetics using sensory components. In a broader context, MEART educates the public about neuroscience, neural interfaces, and robotics. It has paved the way for critical discussions on the future of bio-art and of biotechnology.

  7. NIR fluorescent chitosan-based nanoparticles for tracking and delivery of cancer therapeutic molecule in living systems

    Science.gov (United States)

    Suarato, Giulia; Chin, Amanda; Meng, Yizhi

    2013-03-01

    Tumor metastasis is associated with the epithelial-to-mesenchymal transition (EMT), in which cells lose their polarized phenotype to acquire the asymmetry and motility of mesenchymal cells. Among the many molecular determinants for EMT is bone morphogenetic protein-7 (BMP-7), a critical regulator of skeletal tissue formation and kidney development. Current treatments for metastatic cancer primarily involve surgery and chemotherapy, both with considerable side effects. Therefore the goal of our research is to evaluate the ability of BMP-7 to reverse EMT using a delivery system based on glycol chitosan nanoparticles (GCNP), naturally biodegradable. The GCNP are labeled with Cy5.5, a near infrared (NIR) excitable dye that enables non-invasive imaging in living systems. The chitosan shell provides affinity for the cell surface and protection from intracellular enzymes during transport. Preliminary data show that Cy5.5-GCNP vehicles were successfully delivered to murine preosteoblast (MC3T3-E1), rat osteosarcoma (ROS) 17/2.8 and human embryonic kidney (HEK293) cells. Release kinetics using a model protein (BSA) and BMP-7, and the stability of the protein nano-cargo are currently being evaluated. Cell morphology will be examined with immunofluorescence microscopy.

  8. Fingerprint Sensors: Liveness Detection Issue and Hardware based Solutions

    Directory of Open Access Journals (Sweden)

    Shahzad Memon

    2012-01-01

    Full Text Available Securing an automated and unsupervised fingerprint recognition system is one of the most critical and challenging tasks in government and commercial applications. In these systems, the detection of liveness of a finger placed on a fingerprint sensor is a major issue that needs to be addressed in order to ensure the credibility of the system. The main focus of this paper is to review the existing fingerprint sensing technologies in terms of liveness detection and discusses hardware based ‘liveness detection’ techniques reported in the literature for automatic fingerprint biometrics.

  9. Dream Robber: Living with Parkinson's disease

    Science.gov (United States)

    ... Current Issue Past Issues Dream Robber: Living with Parkinson's disease Past Issues / Summer 2006 Table of Contents ... effects of levodopa called dyskinesias. Additional Information on Parkinson's Web Links MedlinePlus: http://www.nlm.nih.gov/ ...

  10. Living with heart disease and angina

    Science.gov (United States)

    ... blood sugar at recommended levels. Living a Healthy Lifestyle Some controllable risk factors for heart disease are: ... and partially hydrogenated or hydrogenated fats. These are unhealthy fats that are often found in fried foods, ...

  11. Primary students' conceptions of living things

    Science.gov (United States)

    Legaspi, Britt Anne

    Elementary school teachers are pressed for time throughout the instructional day to teach all curricular areas as expected by states and districts because of the current focus on reading and mathematics. Thus, foundational science concepts may be overlooked. For example, students' understandings of living and nonliving things may be overlooked by teachers, yet is useful in understanding the nature of living things. In this qualitative study, K-3 grade students were asked to sort objects as either living or nonliving and to give rationales for their choices. It was found that K-3 students readily used physical characteristics, such as having body parts, and physical abilities, such as being able to move, as criteria for living things. Students in grades 1 through 3 were able to articulate their reasons with more adult-like logic based on Jean Piaget' s research on developmental stages.

  12. Practical applications of short-lived radioisotopes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1963-01-15

    The advantages of the use of short-lived radioisotopes in agriculture, food industry and medicine as well as some industrial uses are discussed. Methods for isotope production in small research reactors and laboratories are presented

  13. Storing data encoded DNA in living organisms

    Science.gov (United States)

    Wong,; Pak C. , Wong; Kwong K. , Foote; Harlan, P [Richland, WA

    2006-06-06

    Current technologies allow the generation of artificial DNA molecules and/or the ability to alter the DNA sequences of existing DNA molecules. With a careful coding scheme and arrangement, it is possible to encode important information as an artificial DNA strand and store it in a living host safely and permanently. This inventive technology can be used to identify origins and protect R&D investments. It can also be used in environmental research to track generations of organisms and observe the ecological impact of pollutants. Today, there are microorganisms that can survive under extreme conditions. As well, it is advantageous to consider multicellular organisms as hosts for stored information. These living organisms can provide as memory housing and protection for stored data or information. The present invention provides well for data storage in a living organism wherein at least one DNA sequence is encoded to represent data and incorporated into a living organism.

  14. CDC Vital Signs: HIV Care Saves Lives

    Science.gov (United States)

    ... gov . Vital Signs Topics Covered Alcohol Antibiotic Resistance Cancer Cardiovascular Diseases Diseases & Conditions Food Safety Healthcare-associated Infections Healthy Living HIV / AIDS Injury, Violence & Safety Motor Vehicle Safety Obesity ...

  15. Quantification of nanowire uptake by live cells

    KAUST Repository

    Margineanu, Michael B.

    2015-01-01

    attempts have been made at tagging and investigating their interaction with living cells. In this study, magnetic iron nanowires with an iron oxide layer are coated with (3-Aminopropyl)triethoxysilane (APTES), and subsequently labeled with a fluorogenic p

  16. Tailor-Made Live Kidney Donation

    NARCIS (Netherlands)

    K.W.J. Klop (Karel)

    2014-01-01

    markdownabstract__Abstract__ This thesis describes several aspects of live kidney donation, such as surgical techniques, cost-effectivity, cosmetics en quality of life. Kidney transplantation offer several benefits when compared to dialysis. These benefits include better recipient and graft

  17. FORUM Paediatric living donor liver transplantation

    African Journals Online (AJOL)

    879 November 2012, Vol. 102, No. 11 SAMJ. REVIEW. Paediatric living donor liver transplantation ... been excellent after left lateral segmentectomy, with a usually quoted ... has led to the development of new surgical techniques to increase.

  18. Products to Aid in Daily Living

    Science.gov (United States)

    ... by The Association, nor a guarantee of the reliability of the information or product. For further information ... Information ALS Insight Newsletter Living with ALS Resource Guides Families and ALS Resource Guide Familial ALS Resource ...

  19. A Smart Kitchen for Ambient Assisted Living

    OpenAIRE

    Blasco, Rubén; Marco, Álvaro; Casas, Roberto; Cirujano, Diego; Picking, Richard

    2014-01-01

    The kitchen environment is one of the scenarios in the home where users can benefit from Ambient Assisted Living (AAL) applications. Moreover, it is the place where old people suffer from most domestic injuries. This paper presents a novel design, implementation and assessment of a Smart Kitchen which provides Ambient Assisted Living services; a smart environment that increases elderly and disabled people’s autonomy in their kitchen-related activities through context and user awareness, appr...

  20. Reaction of long-lived radicals and vitamin C in γ-irradiated mammalian cells and their model system at 295 K. Tunneling reaction in biological system

    International Nuclear Information System (INIS)

    Matsumoto, Takuro; Kumada, Takayuki; Kodama, Seiji; Watanabe, Masami

    1997-01-01

    When golden hamster embryo (GHE) cells or concentrated albumin solution (0.1 kg dm -3 ), that is a model system of cells, is irradiated with γ-rays at 295 K, organic radicals produced can be observed by ESR. The organic radicals survive at both 295 and 310 K for as long as 20 h. The long-lived radicals in GHE cells and the albumin solution react with vitamin C by the rate constants of 0.007 dm 3 mol -1 s -1 and 0.014 dm 3 mol -1 s -1 , respectively. The long-lived radicals in human cells cause gene mutation, which is suppressed by the addition of vitamin C. The isotope effect on the rate constant (κ) for the reaction of the long-lived radicals and vitamin C has been studied in the albumin solution by use of protonated vitamin C and deuterated vitamin C. The isotope effect (κ H /κ D ) was more than 20 ∼ 50 and was interpreted in terms of tunnelling reaction. (author)

  1. Medicaid expenditures for children living with smokers

    Directory of Open Access Journals (Sweden)

    Levy Douglas E

    2011-05-01

    Full Text Available Abstract Background Children's exposure to secondhand smoke is associated with increased morbidity. We estimated Medicaid expenditures for children living with smokers compared to those living with no smokers in the United States. Methods Data were overall and service-specific (i.e., inpatient, ambulatory, emergency department, prescription drug, and dental annual Medicaid expenditures for children 0-11 years old from the 2000-2007 Medical Expenditures Panel Surveys. Smokers' presence in households was determined by adult respondents' self reports. There were 25,835 person-years of observation. We used multivariate analyses to adjust for child, parent, and geographic characteristics. Results Children with Medicaid expenditures were nearly twice as likely to live with a smoker as other children in the U.S. population. Adjusted analyses revealed no detectable differences in children's overall Medicaid expenditures by presence of smokers in the household. Medicaid children who lived with smokers on average had $10 (95% CI $3, $18 higher emergency department expenditures per year than those living with no smokers. Conclusions Living with at least one smoker (a proxy for secondhand smoke exposure is unrelated to children's overall short-term Medicaid expenditures, but has a modest impact on emergency department expenditures. Additional research is necessary to understand the relationship between secondhand smoke exposure and long-term health and economic outcomes.

  2. Just love in live organ donation.

    Science.gov (United States)

    Zeiler, Kristin

    2009-08-01

    Emotionally-related live organ donation is different from almost all other medical treatments in that a family member or, in some countries, a friend contributes with an organ or parts of an organ to the recipient. Furthermore, there is a long-acknowledged but not well-understood gender-imbalance in emotionally-related live kidney donation. This article argues for the benefit of the concept of just love as an analytic tool in the analysis of emotionally-related live organ donation where the potential donor(s) and the recipient are engaged in a love relation. The concept of just love is helpful in the analysis of these live organ donations even if no statistical gender-imbalance prevails. It is particularly helpful, however, in the analysis of the gender-imbalance in live kidney donations if these donations are seen as a specific kind of care-work, if care-work is experienced as a labour one should perform out of love and if women still experience stronger pressures to engage in care-work than do men. The aim of the article is to present arguments for the need of just love as an analytic tool in the analysis of emotionally-related live organ donation where the potential donor(s) and the recipient are engaged in a love relation. The aim is also to elaborate two criteria that need to be met in order for love to qualify as just and to highlight certain clinical implications.

  3. Renal Transplantation from Elderly Living Donors

    Directory of Open Access Journals (Sweden)

    Jacob A. Akoh

    2013-01-01

    Full Text Available Acceptance of elderly living kidney donors remains controversial due to the higher incidence of comorbidity and greater risk of postoperative complications. This is a review of publications in the English language between 2000 and 2013 about renal transplantation from elderly living donors to determine trends and effects of donation, and the outcomes of such transplantation. The last decade witnessed a 50% increase in living kidney donor transplants, with a disproportionate increase in donors >60 years. There is no accelerated loss of kidney function following donation, and the incidence of established renal failure (ERF and hypertension among donors is similar to that of the general population. The overall incidence of ERF in living donors is about 0.134 per 1000 years. Elderly donors require rigorous assessment and should have a predicted glomerular filtration rate of at least 37.5 mL/min/1.73 m2 at the age of 80. Though elderly donors had lower glomerular filtration rate before donation, proportionate decline after donation was similar in both young and elderly groups. The risks of delayed graft function, acute rejection, and graft failure in transplants from living donors >65 years are significantly higher than transplants from younger donors. A multicentred, long-term, and prospective database addressing the outcomes of kidneys from elderly living donors is recommended.

  4. Should We Formulate an Incentivized Model Facilitating Kidney Donation from Living Donors? A Focus on Turkey's Current System.

    Science.gov (United States)

    Avci, Ercan

    2018-04-23

    Kidney transplantation is a lifesaving medical treatment. However, very high demand for kidneys with low kidney donation causes a black market that exploits patients' desperation and donors' vulnerability. The current kidney donation programs fail to produce promising results to avoid illegal and unethical kidney trafficking and commercialism. Even though the primary goal of kidney donation is to increase the number of deceased organ donations, in some countries, like Turkey, due to religious or cultural concerns, it is impossible to supply adequate deceased kidney donations. In this view, the aim of this paper is to examine kidney trafficking in the scope of Turkey's current organ donation system and propose a new model, named the Incentivized Kidney Donation Model (IKDM), to increase kidney donation from living donors. The model encompasses the following benefits offered to kidney donors; lifetime health insurance, exemptions from copayments/contribution shares, priority when receiving an organ, priority when finding a job, income tax exemptions for salaried employees, and free or discounted public utilities. This normative model has the potential to promote donors' altruistic acts as well as the solidarity and loyalty among members of a society without violating ethical values and internationally accepted principles. © 2018 John Wiley & Sons Ltd.

  5. Toward High School Biology: Helping Middle School Students Understand Chemical Reactions and Conservation of Mass in Nonliving and Living Systems

    Science.gov (United States)

    Herrmann-Abell, Cari F.; Koppal, Mary; Roseman, Jo Ellen

    2016-01-01

    Modern biology has become increasingly molecular in nature, requiring students to understand basic chemical concepts. Studies show, however, that many students fail to grasp ideas about atom rearrangement and conservation during chemical reactions or the application of these ideas to biological systems. To help provide students with a better foundation, we used research-based design principles and collaborated in the development of a curricular intervention that applies chemistry ideas to living and nonliving contexts. Six eighth grade teachers and their students participated in a test of the unit during the Spring of 2013. Two of the teachers had used an earlier version of the unit the previous spring. The other four teachers were randomly assigned either to implement the unit or to continue teaching the same content using existing materials. Pre- and posttests were administered, and the data were analyzed using Rasch modeling and hierarchical linear modeling. The results showed that, when controlling for pretest score, gender, language, and ethnicity, students who used the curricular intervention performed better on the posttest than the students using existing materials. Additionally, students who participated in the intervention held fewer misconceptions. These results demonstrate the unit’s promise in improving students’ understanding of the targeted ideas. PMID:27909024

  6. Neutron-captures in Low Mass Stars and the Early Solar System Record of Short-lived Radioactivities

    Science.gov (United States)

    Busso, Maurizio; Vescovi, Diego; Trippella, Oscar; Palmerini, Sara; Cristallo, Sergio; Piersanti, Luciano

    2018-01-01

    Noticeable improvements were recently introduced in the modelling of n-capture nucleosynthesis in the advanced evolutionary stages of giant stars (Asymptotic Giant Branch, or AGB, stars). Two such improvements are closely linked together and concern the introduction of non-parameterized, physical models for extended mixing processes and the adoption of accurate reaction rates for H- and He-burning reactions, including the one for the main neutron source 13C(α,n)16O. These improvements profited of a longstanding collaboration between stellar physicists and C. Spitaleri's team and of his seminal work both as a leader in the Nuclear Astrophysics scenario and as a talent-scout in the recruitment of young researchers in the field. We present an example of the innovative results that can be obtained thanks to the novelties introduced, by estimating the contributions from a nearby AGB star to the synthesis of short-lived (t1/2 ≤ 10 Myr) radioactive nuclei which were alive in early Solar System condensates. We find that the scenario indicating an AGB star as the source of such radioactivities, discussed for many years by researchers in this field, appears now to be no longer viable, when the mentioned improvements of AGB models and nuclear parameters are considered.

  7. The mechanism and properties of bio-photon emission and absorption in protein molecules in living systems

    Science.gov (United States)

    Pang, Xiao-feng

    2012-05-01

    The mechanism and properties of bio-photon emission and absorption in bio-tissues were studied using Pang's theory of bio-energy transport, in which the energy spectra of protein molecules are obtained from the discrete dynamic equation. From the energy spectra, it was determined that the protein molecules could both radiate and absorb bio-photons with wavelengths of energy level transitions of the excitons. These results were consistent with the experimental data; this consisted of infrared absorption data from collagen, bovine serum albumin, the protein-like molecule acetanilide, plasma, and a person's finger, and the laser-Raman spectra of acidity I-type collagen in the lungs of a mouse, and metabolically active Escherichia coli. We further elucidated the mechanism responsible for the non-thermal biological effects produced by the infrared light absorbed by the bio-tissues, using the above results. No temperature rise was observed; instead, the absorbed infrared light promoted the vibrations of amides as well the transport of the bio-energy from one place to other in the protein molecules, which changed their conformations. These experimental results, therefore, not only confirmed the validity of the mechanism of bio-photon emission, and the newly developed theory of bio-energy transport mentioned above, but also explained the mechanism and properties of the non-thermal biological effects produced by the absorption of infrared light by the living systems.

  8. Patients' Perspectives and Experiences Living with Systemic Sclerosis: A Systematic Review and Thematic Synthesis of Qualitative Studies.

    Science.gov (United States)

    Nakayama, Ayano; Tunnicliffe, David J; Thakkar, Vivek; Singh-Grewal, Davinder; O'Neill, Sean; Craig, Jonathan C; Tong, Allison

    2016-07-01

    Systemic sclerosis (SSc) is a chronic, progressive autoimmune disease with major end-organ involvement. Much attention has been focused on the management of physical and clinical manifestations; however, the effect of the disease and treatment on the patient's identity, relationships, functioning, and mental well-being are less known. We aimed to describe the patients' perspectives and experiences of living with SSc. Electronic databases were searched to October 2014. Thematic synthesis was used to analyze the findings. We included 26 studies involving 463 patients. Six key themes were identified: distressing appearance transformation (disturbing facial changes, stigmatizing sickness, unrecognizable self), palpable physical limitations (bodily restrictions, frustrating mind-body disconnect, pervasive fatigue, disabling pain), social impairment (breaking intimacy, struggling to fulfill family responsibilities, maintaining work, losing independence), navigating uncertainty (diagnostic ambiguity, medically fending for oneself, unpredictable course of illness), alone and misunderstood (fearful avoidance of fellow patients, invisible suffering), and gradual acceptance and relative optimism (adapting to change and accepting limitations, taking a positive spin, cautious hoping, empowering relationships, valuing medical support). SSc is a rare and unpredictable illness that undermines patients' sense of certainty and control and impairs their self-image, identity, and daily functioning. Patient-centered care that encompasses strategies to promote self-esteem, resilience, and self-efficacy may help to improve treatment satisfaction and health and quality of life outcomes for patients with SSc.

  9. [Prediction of life expectancy for prostate cancer patients based on the kinetic theory of aging of living systems].

    Science.gov (United States)

    Viktorov, A A; Zharinov, G M; Neklasova, N Ju; Morozova, E E

    2017-01-01

    The article presents a methodical approach for prediction of life expectancy for people diagnosed with prostate cancer based on the kinetic theory of aging of living systems. The life expectancy is calculated by solving the differential equation for the rate of aging for three different stage of life - «normal» life, life with prostate cancer and life after combination therapy for prostate cancer. The mathematical model of aging for each stage of life has its own parameters identified by the statistical analysis of healthcare data from the Zharinov's databank and Rosstat CDR NES databank. The core of the methodical approach is the statistical correlation between growth rate of the prostate specific antigen level (PSA-level) or the PSA doubling time (PSA DT) before therapy, and lifespan: the higher the PSA DT is, the greater lifespan. The patients were grouped under the «fast PSA DT» and «slow PSA DT» categories. The satisfactory matching between calculations and experiment is shown. The prediction error of group life expectancy is due to the completeness and reliability of the main data source. A detailed monitoring of the basic health indicators throughout the each person life in each analyzed group is required. The absence of this particular information makes it impossible to predict the individual life expectancy.

  10. On the Prototyping of an ICT-Enhanced Toilet System for Assisting Older Persons Living Independently and Safely at Home.

    Science.gov (United States)

    Panek, Paul; Fazekas, Gabor; Lüftenegger, Theresa; Mayer, Peter; Pilissy, Tamas; Raffaelli, Matteo; Rist, Atilla; Rosenthal, Ramona; Savanovic, Arso; Sobjak, Anna; Sonntag, Franziska; Toth, Andras; Unger, Birgit

    2017-01-01

    Standard toilets often do not meet the needs of a significant number of older persons and persons with disabilities. The EU funded iToilet project aims at design and development of a new type of ICT enhanced modular toilet system which shall be able to support autonomy, dignity and safety of older persons living at home. Methodologically the project started with gathering user requirements by means of questionnaires, interviews and focus group discussion involving a total of 74 persons, thereof 41 subjects with movement disorders (primary users), 21 caregivers (secondary users) and 12 healthcare managers (tertiary users). Most important wishes were bilateral removable handrails, height and tilt adjustment, emergency detection, simplicity. In parallel to the ongoing technical development participatory design activities have been carried out at user test sites in order to continuously involve users into the design process and to allow quick feedback with regards to early prototype parts. The project currently is working on the finalization of the first prototype ready to enter the lab trial stage in spring 2017. The experiences will be used for redesigning a prototype 2 which is planned to be tested in real life settings early 2018.

  11. Rocky Flats Plant Live-Fire Range Risk Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Nicolosi, S.L.; Rodriguez, M.A.

    1994-04-01

    The objective of the Live-Fire Range Risk Analysis Report (RAR) is to provide an authorization basis for operation as required by DOE 5480.16. The existing Live-Fire Range does not have a safety analysis-related authorization basis. EG&G Rocky Flats, Inc. has worked with DOE and its representatives to develop a format and content description for development of an RAR for the Live-Fire Range. Development of the RAR is closely aligned with development of the design for a baffle system to control risks from errant projectiles. DOE 5480.16 requires either an RAR or a safety analysis report (SAR) for live-fire ranges. An RAR rather than a SAR was selected in order to gain flexibility to more closely address the safety analysis and conduct of operation needs for a live-fire range in a cost-effective manner.

  12. Live face detection based on the analysis of Fourier spectra

    Science.gov (United States)

    Li, Jiangwei; Wang, Yunhong; Tan, Tieniu; Jain, Anil K.

    2004-08-01

    Biometrics is a rapidly developing technology that is to identify a person based on his or her physiological or behavioral characteristics. To ensure the correction of authentication, the biometric system must be able to detect and reject the use of a copy of a biometric instead of the live biometric. This function is usually termed "liveness detection". This paper describes a new method for live face detection. Using structure and movement information of live face, an effective live face detection algorithm is presented. Compared to existing approaches, which concentrate on the measurement of 3D depth information, this method is based on the analysis of Fourier spectra of a single face image or face image sequences. Experimental results show that the proposed method has an encouraging performance.

  13. Pressure Safety: Advanced Live 11459

    Energy Technology Data Exchange (ETDEWEB)

    Glass, George [Los Alamos National Laboratory

    2016-03-02

    Many Los Alamos National Laboratory (LANL) operations use pressure equipment and systems. Failure to follow proper procedures when designing or operating pressure systems can result in injuries to personnel and damage to equipment and/or the environment. This manual presents an overview of the requirements and recommendations that address the safe design and operation of pressure systems at LANL.

  14. New epistemological foundations for cultural psychology: from an atomistic to a self-organizing view of living systems.

    Science.gov (United States)

    De Pascale, Adele

    2014-01-01

    An epistemological foundation for cultural psychology is essential to neuro- and behavioural sciences for the challenge psychological sciences must currently face: searching for an explanation of how a brain can become a mind and how individuals assign a sense to the world and their life. Biological systems are very likely determined by physical and chemical laws of spontaneous self-organization and endogenous constraints but, even if the major result of the Darwinian revolution is "the discovery that living species are their story", the modern synthesis of the evolution theory adopted only continuist and gradualist hypotheses. This nourished the analogy between the theory of natural selection and the theory of operant conditioning, thereby supporting empiricist associationism and the methodological positivism of behavioural and "classical" cognitive psychologists. Current scientific contributions provide evidence to the need for psychotherapy and psychopathology of a new epistemological approach in order to connect research stemming from animal models, up to the most abstract levels of personal meaning. The complex system oriented approach, here described, called "post-rationalism", shaped by a change initiated by evolutionary epistemology. The regulation of emotions initially develops within interpersonal relationships and evolves during both phylogeny and ontogeny, according to complex self-organization processes, leading to the acquisition of Self-organizing abilities and the construction of personal meaning. Endorsing the epistemological similarities of neo-Darwinism and behaviourism, and differentiating from this, the above mentioned approach, emphasises the fact that clinical and psycho-therapeutical practice must be founded on the laws of biological organisation: the ongoing activity of neurobiological systems, including the more abstract domains of thought and language.

  15. New epistemological foundations for cultural psychology: from an atomistic to a self-organizing view of living systems

    Directory of Open Access Journals (Sweden)

    Adele De Pascale

    2014-09-01

    Full Text Available An epistemological foundation for cultural psychology is essential to neuro- and behavioural sciences for the challenge psychological sciences must currently face: searching for an explanation of how a brain can become a mind and how individuals assign a sense to the world and their life. Biological systems are very likely determined by physical and chemical laws of spontaneous self-organization and endogenous constraints but, even if the major result of the Darwinian revolution is "the discovery that living species are their story", the modern synthesis of the evolution theory adopted only continuist and gradualist hypotheses. This nourished the analogy between the theory of natural selection and the theory of operant conditioning, thereby supporting empiricist associationism and the methodological positivism of behavioural and "classical" cognitive psychologists. Current scientific contributions provide evidence to the need for psychotherapy and psychopathology of a new epistemological approach in order to connect research stemming from animal models, up to the most abstract levels of personal meaning. The complex system oriented approach, here described, called "post-rationalism", shaped by a change initiated by evolutionary epistemology. The regulation of emotions initially develops within interpersonal relationships and evolves during both phylogeny and ontogeny, according to complex self-organization processes, leading to the acquisition of Self-organizing abilities and the construction of personal meaning. Endorsing the epistemological similarities of neo-Darwinism and behaviourism, and differentiating from this, the above mentioned approach, emphasises the fact that clinical and psycho-therapeutical practice must be founded on the laws of biological organisation: the ongoing activity of neurobiological systems, including the more abstract domains of thought and language.

  16. Wayfinding the Live 5-2-1-0 Initiative-At the Intersection between Systems Thinking and Community-Based Childhood Obesity Prevention.

    Science.gov (United States)

    Amed, Shazhan; Shea, Stephanie; Pinkney, Susan; Wharf Higgins, Joan; Naylor, Patti-Jean

    2016-06-21

    Childhood obesity is complex and requires a 'systems approach' that collectively engages across multiple community settings. Sustainable Childhood Obesity Prevention through Community Engagement (SCOPE) has implemented Live 5-2-1-0-a multi-sector, multi-component childhood obesity prevention initiative informed by systems thinking and participatory research via an innovative knowledge translation (KT) model (RE-FRAME). This paper describes the protocol for implementing and evaluating RE-FRAME in two 'existing' (>2 years of implementation) and two 'new' Live 5-2-1-0 communities to understand how to facilitate and sustain systems/community-level change. In this mixed-methods study, RE-FRAME was implemented via online resources, webinars, a backbone organization (SCOPE) coordinating the initiative, and a linking system supporting KT. Qualitative and quantitative data were collected using surveys and stakeholder interviews, analyzed using thematic analysis and descriptive statistics, respectively. Existing communities described the consistency of Live 5-2-1-0 and extensive local partnerships/champions as catalysts for synergistic community-wide action; new communities felt that the simplicity of the message combined with the transfer of experiential learning would inform their own strategies and policies/programs to broadly disseminate Live 5-2-1-0. RE-FRAME effectively guided the refinement of the initiative and provided a framework upon which evaluation results described how to implement a community-based systems approach to childhood obesity prevention.

  17. Long-lived coherence in carotenoids

    Energy Technology Data Exchange (ETDEWEB)

    Davis, J A; Cannon, E; Van Dao, L; Hannaford, P [ARC Centre of Excellence for Coherent X-ray Science, Centre for Atom Optics and Ultrafast Spectroscopy, Swinburne University of Technology, Victoria 3122 (Australia); Quiney, H M; Nugent, K A, E-mail: jdavis@swin.edu.a [ARC Centre of Excellence for Coherent X-ray Science, School of Physics, University of Melbourne, Victoria 3010 (Australia)

    2010-08-15

    We use two-colour vibronic coherence spectroscopy to observe long-lived vibrational coherences in the ground electronic state of carotenoid molecules, with decoherence times in excess of 1 ps. Lycopene and spheroidene were studied isolated in solution, and within the LH2 light-harvesting complex extracted from purple bacteria. The vibrational coherence time is shown to increase significantly for the carotenoid in the complex, providing further support to previous assertions that long-lived electronic coherences in light-harvesting complexes are facilitated by in-phase motion of the chromophores and surrounding proteins. Using this technique, we are also able to follow the evolution of excited state coherences and find that for carotenoids in the light-harvesting complex the (S{sub 2}|S{sub 0}) superposition remains coherent for more than 70 fs. In addition to the implications of this long electronic decoherence time, the extended coherence allows us to observe the evolution of the excited state wavepacket. These experiments reveal an enhancement of the vibronic coupling to the first vibrational level of the C-C stretching mode and/or methyl-rocking mode in the ground electronic state 70 fs after the initial excitation. These observations open the door to future experiments and modelling that may be able to resolve the relaxation dynamics of carotenoids in solution and in natural light-harvesting systems.

  18. Synthetic analog computation in living cells.

    Science.gov (United States)

    Daniel, Ramiz; Rubens, Jacob R; Sarpeshkar, Rahul; Lu, Timothy K

    2013-05-30

    A central goal of synthetic biology is to achieve multi-signal integration and processing in living cells for diagnostic, therapeutic and biotechnology applications. Digital logic has been used to build small-scale circuits, but other frameworks may be needed for efficient computation in the resource-limited environments of cells. Here we demonstrate that synthetic analog gene circuits can be engineered to execute sophisticated computational functions in living cells using just three transcription factors. Such synthetic analog gene circuits exploit feedback to implement logarithmically linear sensing, addition, ratiometric and power-law computations. The circuits exhibit Weber's law behaviour as in natural biological systems, operate over a wide dynamic range of up to four orders of magnitude and can be designed to have tunable transfer functions. Our circuits can be composed to implement higher-order functions that are well described by both intricate biochemical models and simple mathematical functions. By exploiting analog building-block functions that are already naturally present in cells, this approach efficiently implements arithmetic operations and complex functions in the logarithmic domain. Such circuits may lead to new applications for synthetic biology and biotechnology that require complex computations with limited parts, need wide-dynamic-range biosensing or would benefit from the fine control of gene expression.

  19. Long-lived coherence in carotenoids

    International Nuclear Information System (INIS)

    Davis, J A; Cannon, E; Van Dao, L; Hannaford, P; Quiney, H M; Nugent, K A

    2010-01-01

    We use two-colour vibronic coherence spectroscopy to observe long-lived vibrational coherences in the ground electronic state of carotenoid molecules, with decoherence times in excess of 1 ps. Lycopene and spheroidene were studied isolated in solution, and within the LH2 light-harvesting complex extracted from purple bacteria. The vibrational coherence time is shown to increase significantly for the carotenoid in the complex, providing further support to previous assertions that long-lived electronic coherences in light-harvesting complexes are facilitated by in-phase motion of the chromophores and surrounding proteins. Using this technique, we are also able to follow the evolution of excited state coherences and find that for carotenoids in the light-harvesting complex the (S 2 |S 0 ) superposition remains coherent for more than 70 fs. In addition to the implications of this long electronic decoherence time, the extended coherence allows us to observe the evolution of the excited state wavepacket. These experiments reveal an enhancement of the vibronic coupling to the first vibrational level of the C-C stretching mode and/or methyl-rocking mode in the ground electronic state 70 fs after the initial excitation. These observations open the door to future experiments and modelling that may be able to resolve the relaxation dynamics of carotenoids in solution and in natural light-harvesting systems.

  20. The DFKI Competence Center for Ambient Assisted Living

    Science.gov (United States)

    Frey, Jochen; Stahl, Christoph; Röfer, Thomas; Krieg-Brückner, Bernd; Alexandersson, Jan

    The DFKI Competence Center for Ambient Assisted Living (CCAAL) is a cross-project and cross-department virtual organization within the German Research Center for Artificial Intelligence coordinating and conducting research and development in the area of Ambient Assisted Living (AAL). Our demonstrators range from multimodal speech dialog systems to fully instrumented environments allowing the development of intelligent assistant systems, for instance an autonomous wheelchair, or the recognition and processing of everyday activities in a smart home. These innovative technologies are then tested, evaluated and demonstrated in DFKI's living labs.