WorldWideScience

Sample records for links simple search

  1. Does linear separability really matter? Complex visual search is explained by simple search

    Science.gov (United States)

    Vighneshvel, T.; Arun, S. P.

    2013-01-01

    Visual search in real life involves complex displays with a target among multiple types of distracters, but in the laboratory, it is often tested using simple displays with identical distracters. Can complex search be understood in terms of simple searches? This link may not be straightforward if complex search has emergent properties. One such property is linear separability, whereby search is hard when a target cannot be separated from its distracters using a single linear boundary. However, evidence in favor of linear separability is based on testing stimulus configurations in an external parametric space that need not be related to their true perceptual representation. We therefore set out to assess whether linear separability influences complex search at all. Our null hypothesis was that complex search performance depends only on classical factors such as target-distracter similarity and distracter homogeneity, which we measured using simple searches. Across three experiments involving a variety of artificial and natural objects, differences between linearly separable and nonseparable searches were explained using target-distracter similarity and distracter heterogeneity. Further, simple searches accurately predicted complex search regardless of linear separability (r = 0.91). Our results show that complex search is explained by simple search, refuting the widely held belief that linear separability influences visual search. PMID:24029822

  2. Search without Boundaries Using Simple APIs

    Science.gov (United States)

    Tong, Qi

    2009-01-01

    The U.S. Geological Survey (USGS) Library, where the author serves as the digital services librarian, is increasingly challenged to make it easier for users to find information from many heterogeneous information sources. Information is scattered throughout different software applications (i.e., library catalog, federated search engine, link resolver, and vendor websites), and each specializes in one thing. How could the library integrate the functionalities of one application with another and provide a single point of entry for users to search across? To improve the user experience, the library launched an effort to integrate the federated search engine into the library's intranet website. The result is a simple search box that leverages the federated search engine's built-in application programming interfaces (APIs). In this article, the author describes how this project demonstrated the power of APIs and their potential to be used by other enterprise search portals inside or outside of the library.

  3. Age differences in search of web pages: the effects of link size, link number, and clutter.

    Science.gov (United States)

    Grahame, Michael; Laberge, Jason; Scialfa, Charles T

    2004-01-01

    Reaction time, eye movements, and errors were measured during visual search of Web pages to determine age-related differences in performance as a function of link size, link number, link location, and clutter. Participants (15 young adults, M = 23 years; 14 older adults, M = 57 years) searched Web pages for target links that varied from trial to trial. During one half of the trials, links were enlarged from 10-point to 12-point font. Target location was distributed among the left, center, and bottom portions of the screen. Clutter was manipulated according to the percentage of used space, including graphics and text, and the number of potentially distracting nontarget links was varied. Increased link size improved performance, whereas increased clutter and links hampered search, especially for older adults. Results also showed that links located in the left region of the page were found most easily. Actual or potential applications of this research include Web site design to increase usability, particularly for older adults.

  4. SpEnD: Linked Data SPARQL Endpoints Discovery Using Search Engines

    OpenAIRE

    Yumusak, Semih; Dogdu, Erdogan; Kodaz, Halife; Kamilaris, Andreas

    2016-01-01

    In this study, a novel metacrawling method is proposed for discovering and monitoring linked data sources on the Web. We implemented the method in a prototype system, named SPARQL Endpoints Discovery (SpEnD). SpEnD starts with a "search keyword" discovery process for finding relevant keywords for the linked data domain and specifically SPARQL endpoints. Then, these search keywords are utilized to find linked data sources via popular search engines (Google, Bing, Yahoo, Yandex). By using this ...

  5. New Searching Capability and OpenURL Linking in the ADS

    Science.gov (United States)

    Eichhorn, Guenther; Accomazzi, A.; Grant, C. S.; Henneken, E.; Kurtz, M. J.; Thompson, D. M.; Murray, S. S.

    2006-12-01

    The ADS is the search system of choice for the astronomical community. It also covers a large part of the physics and physics/astronomy education literature. In order to make access to this system as easy as possible, we developed a Google-like interface version of our search form. This one-field search parses the user input and automatically detects author names and year ranges. Firefox users can set up their browser to have this search field installed in the top right corner search field to have even easier access to the ADS search capability. The basic search is available from the ADS Homepage at: http://adsabs.harvard.edu To aid with access to subscription journals the ADS now supports OpenURL linking. If your library supports an OpenURL server, you can specify this server in the ADS preference settings. All links to journal articles will then automatically be directed to the OpenURL with the appropriate link information. We provide a selection of known OpenURL servers to choose from. If your server is not in this list, please send the necessary information to ads@cfa.harvard.edu and we will include it in our list. The ADS is funded by NASA grant NNG06GG68G.

  6. SpEnD: Linked Data SPARQL Endpoints Discovery Using Search Engines

    Science.gov (United States)

    Yumusak, Semih; Dogdu, Erdogan; Kodaz, Halife; Kamilaris, Andreas; Vandenbussche, Pierre-Yves

    In this study, a novel metacrawling method is proposed for discovering and monitoring linked data sources on the Web. We implemented the method in a prototype system, named SPARQL Endpoints Discovery (SpEnD). SpEnD starts with a "search keyword" discovery process for finding relevant keywords for the linked data domain and specifically SPARQL endpoints. Then, these search keywords are utilized to find linked data sources via popular search engines (Google, Bing, Yahoo, Yandex). By using this method, most of the currently listed SPARQL endpoints in existing endpoint repositories, as well as a significant number of new SPARQL endpoints, have been discovered. Finally, we have developed a new SPARQL endpoint crawler (SpEC) for crawling and link analysis.

  7. A SIMPLE Bubble Chamber for Dark Matter Searches: Testing and Development

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, A.R.; Fernandes, A.C.; Marques, J.G.; Kling, A. [C2TN, Instituto Superior Tecnico, Universidade de Lisboa, E.N. 10 - km 139.7, 2695-066 Bobadela, LRS (Portugal); Felizardo, M.; Girard, T.A. [Centro de Fisica Nuclear, Universidade de Lisboa, Av. Prof. Gama Pinto 2, 1649-003, Lisbon (Portugal); Lazaro, I. [Laboratoire Souterrain a Bas Bruit, UMS 3538 UNS/UAPV/CNRS, 84400 Rustrel-Pays d' Apt (France); Puibasset, J. [Centre de Recherche sur la Matiere Divisee CNRS et Universite d' Orleans, 45071 Orleans, 02 (France)

    2015-07-01

    SIMPLE (Superheated Instrument for Massive Particle Experiments) is one of only three experiments worldwide in search of evidence of astroparticle dark matter (WIMPs) using halocarbon-loaded superheated liquid (SHL) detectors. The 2012 Phase II SIMPLE measurements yielded the most restrictive exclusion contour in the spin-dependent (SD) sector of WIMP-proton interactions from a direct search experiment at the time, overlapping for the first time results previously obtained only indirectly [1]. In order to remain competitive with other experiments in the field, the next phase measurement requires larger exposure over shorter observation times with significantly improved neutron shielding. To increase exposure, SIMPLE plans, as a first step, to replace its superheated droplet detectors (SDDs), each containing an active mass of about 15 g of halocarbon, with bubble chambers capable of holding up to 20 kg of active halocarbon mass. We report on the development of the first 1 kg halocarbon SIMPLE bubble chamber prototype, including chamber recompression system design and testing and initial acoustic detection of bubble formation. (authors)

  8. The Race for Sponsored Links: Bidding Patterns for Search Advertising

    OpenAIRE

    Zsolt Katona; Miklos Sarvary

    2010-01-01

    Paid placements on search engines reached sales of nearly $11 billion in the United States last year and represent the most rapidly growing form of online advertising today. In its classic form, a search engine sets up an auction for each search word in which competing websites bid for their sponsored links to be displayed next to the search results. We model this advertising market, focusing on two of its key characteristics: (1) the interaction between the list of search results and the lis...

  9. SIRW: A web server for the Simple Indexing and Retrieval System that combines sequence motif searches with keyword searches.

    Science.gov (United States)

    Ramu, Chenna

    2003-07-01

    SIRW (http://sirw.embl.de/) is a World Wide Web interface to the Simple Indexing and Retrieval System (SIR) that is capable of parsing and indexing various flat file databases. In addition it provides a framework for doing sequence analysis (e.g. motif pattern searches) for selected biological sequences through keyword search. SIRW is an ideal tool for the bioinformatics community for searching as well as analyzing biological sequences of interest.

  10. Emergence of an optimal search strategy from a simple random walk.

    Science.gov (United States)

    Sakiyama, Tomoko; Gunji, Yukio-Pegio

    2013-09-06

    In reports addressing animal foraging strategies, it has been stated that Lévy-like algorithms represent an optimal search strategy in an unknown environment, because of their super-diffusion properties and power-law-distributed step lengths. Here, starting with a simple random walk algorithm, which offers the agent a randomly determined direction at each time step with a fixed move length, we investigated how flexible exploration is achieved if an agent alters its randomly determined next step forward and the rule that controls its random movement based on its own directional moving experiences. We showed that our algorithm led to an effective food-searching performance compared with a simple random walk algorithm and exhibited super-diffusion properties, despite the uniform step lengths. Moreover, our algorithm exhibited a power-law distribution independent of uniform step lengths.

  11. REPTREE CLASSIFIER FOR IDENTIFYING LINK SPAM IN WEB SEARCH ENGINES

    Directory of Open Access Journals (Sweden)

    S.K. Jayanthi

    2013-01-01

    Full Text Available Search Engines are used for retrieving the information from the web. Most of the times, the importance is laid on top 10 results sometimes it may shrink as top 5, because of the time constraint and reliability on the search engines. Users believe that top 10 or 5 of total results are more relevant. Here comes the problem of spamdexing. It is a method to deceive the search result quality. Falsified metrics such as inserting enormous amount of keywords or links in website may take that website to the top 10 or 5 positions. This paper proposes a classifier based on the Reptree (Regression tree representative. As an initial step Link-based features such as neighbors, pagerank, truncated pagerank, trustrank and assortativity related attributes are inferred. Based on this features, tree is constructed. The tree uses the feature inference to differentiate spam sites from legitimate sites. WEBSPAM-UK-2007 dataset is taken as a base. It is preprocessed and converted into five datasets FEATA, FEATB, FEATC, FEATD and FEATE. Only link based features are taken for experiments. This paper focus on link spam alone. Finally a representative tree is created which will more precisely classify the web spam entries. Results are given. Regression tree classification seems to perform well as shown through experiments.

  12. Connectivity algorithm with depth first search (DFS) on simple graphs

    Science.gov (United States)

    Riansanti, O.; Ihsan, M.; Suhaimi, D.

    2018-01-01

    This paper discusses an algorithm to detect connectivity of a simple graph using Depth First Search (DFS). The DFS implementation in this paper differs than other research, that is, on counting the number of visited vertices. The algorithm obtains s from the number of vertices and visits source vertex, following by its adjacent vertices until the last vertex adjacent to the previous source vertex. Any simple graph is connected if s equals 0 and disconnected if s is greater than 0. The complexity of the algorithm is O(n2).

  13. Evaluating aggregated search using interleaving

    NARCIS (Netherlands)

    Chuklin, A.; Schuth, A.; Hofmann, K.; Serdyukov, P.; de Rijke, M.

    2013-01-01

    A result page of a modern web search engine is often much more complicated than a simple list of "ten blue links." In particular, a search engine may combine results from different sources (e.g., Web, News, and Images), and display these as grouped results to provide a better user experience. Such a

  14. Search for linking transitions in {sup 143}Eu

    Energy Technology Data Exchange (ETDEWEB)

    Lerma, F.; LaFosse, D.R.; Devlin, M. [Washington Univ., Saint Louis, MO (United States)] [and others

    1996-12-31

    Six SD bands were populated in {sup 143}Eu and {sup 144}Eu, two of which had not been previously observed. Sum spectra were generated to search for two step links from the yrast SD band in {sup 143}Eu. However, no two step links were found. A single link from the SD band in {sup 143}Eu was found at 3364 keV. The level where it feeds into has not been identified. Alpha-particle energy (E{sub {alpha}}) spectra leading to the SD band and to normal states in {sup 143}Eu were measured and a correlation was found between E{sub {alpha}} and the level spin of the residual nucleus.

  15. The effects of link format and screen location on visual search of web pages.

    Science.gov (United States)

    Ling, Jonathan; Van Schaik, Paul

    2004-06-22

    Navigation of web pages is of critical importance to the usability of web-based systems such as the World Wide Web and intranets. The primary means of navigation is through the use of hyperlinks. However, few studies have examined the impact of the presentation format of these links on visual search. The present study used a two-factor mixed measures design to investigate whether there was an effect of link format (plain text, underlined, bold, or bold and underlined) upon speed and accuracy of visual search and subjective measures in both the navigation and content areas of web pages. An effect of link format on speed of visual search for both hits and correct rejections was found. This effect was observed in the navigation and the content areas. Link format did not influence accuracy in either screen location. Participants showed highest preference for links that were in bold and underlined, regardless of screen area. These results are discussed in the context of visual search processes and design recommendations are given.

  16. Supporting inter-topic entity search for biomedical Linked Data based on heterogeneous relationships.

    Science.gov (United States)

    Zong, Nansu; Lee, Sungin; Ahn, Jinhyun; Kim, Hong-Gee

    2017-08-01

    The keyword-based entity search restricts search space based on the preference of search. When given keywords and preferences are not related to the same biomedical topic, existing biomedical Linked Data search engines fail to deliver satisfactory results. This research aims to tackle this issue by supporting an inter-topic search-improving search with inputs, keywords and preferences, under different topics. This study developed an effective algorithm in which the relations between biomedical entities were used in tandem with a keyword-based entity search, Siren. The algorithm, PERank, which is an adaptation of Personalized PageRank (PPR), uses a pair of input: (1) search preferences, and (2) entities from a keyword-based entity search with a keyword query, to formalize the search results on-the-fly based on the index of the precomputed Individual Personalized PageRank Vectors (IPPVs). Our experiments were performed over ten linked life datasets for two query sets, one with keyword-preference topic correspondence (intra-topic search), and the other without (inter-topic search). The experiments showed that the proposed method achieved better search results, for example a 14% increase in precision for the inter-topic search than the baseline keyword-based search engine. The proposed method improved the keyword-based biomedical entity search by supporting the inter-topic search without affecting the intra-topic search based on the relations between different entities. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Chapter 51: How to Build a Simple Cone Search Service Using a Local Database

    Science.gov (United States)

    Kent, B. R.; Greene, G. R.

    The cone search service protocol will be examined from the server side in this chapter. A simple cone search service will be setup and configured locally using MySQL. Data will be read into a table, and the Java JDBC will be used to connect to the database. Readers will understand the VO cone search specification and how to use it to query a database on their local systems and return an XML/VOTable file based on an input of RA/DEC coordinates and a search radius. The cone search in this example will be deployed as a Java servlet. The resulting cone search can be tested with a verification service. This basic setup can be used with other languages and relational databases.

  18. A simple optical fibre-linked remote control system for multiple devices

    Indian Academy of Sciences (India)

    We report on the development of a simple control system which can handle multiple devices through an optical fibre data link. The devices are controlled using a set of DACs through serial data communication via a serial port of a PC. Serial data from the PC get converted to parallel mode using a homemade “serial in ...

  19. On the Runtime of Randomized Local Search and Simple Evolutionary Algorithms for Dynamic Makespan Scheduling

    DEFF Research Database (Denmark)

    Neumann, Frank; Witt, Carsten

    2015-01-01

    combinatorial optimization problem, namely makespan scheduling. We study the model of a strong adversary which is allowed to change one job at regular intervals. Furthermore, we investigate the setting of random changes. Our results show that randomized local search and a simple evolutionary algorithm are very...

  20. Simple and effective procedure for conformational search of macromolecules. Application to Met- and Leu-Enkephalin

    Energy Technology Data Exchange (ETDEWEB)

    Meirovitch, H.; Meirovitch, E. (Florida State Univ., Tallahassee, FL (United States)); Michel, A.G. (Institut de Recherches Serrier, Suresnes (France)); Vasquez, M. (Protein Design Lab., Mountain View, CA (United States))

    1994-06-23

    A simple and efficient method for searching the conformational space of macromolecules is presented. With this method an initial set of relatively low-energy structures is generated, and their energies are further minimized with a procedure that enables escaping from local energy minima. Illustrative calculations are described for Met- and Leu-enkephalin. 37 refs., 1 tab.

  1. Overview of the CLEF 2016 Social Book Search Lab

    DEFF Research Database (Denmark)

    Koolen, Marijn; Bogers, Toine; Gäde, Maria

    2016-01-01

    systems. The aim of the Interactive Track is to develop user interfaces that support users through each stage during complex search tasks and to investigate how users exploit professional metadata and user-generated content. The Mining Track focuses on detecting and linking book titles in online book......The Social Book Search (SBS) Lab investigates book search in scenarios where users search with more than just a query, and look for more than objective metadata. Real-world information needs are generally complex, yet almost all research focuses instead on either relatively simple search based...... on queries, or on profile-based recommendation. The goal is to research and develop techniques to support users in complex book search tasks. The SBS Lab has three tracks. The aim of the Suggestion Track is to develop test collections for evaluating ranking effectiveness of book retrieval and recommender...

  2. Searching for the Prosocial Personality: A Big Five Approach to Linking Personality and Prosocial Behavior.

    Science.gov (United States)

    Habashi, Meara M; Graziano, William G; Hoover, Ann E

    2016-09-01

    The search for the prosocial personality has been long and controversial. The current research explores the general patterns underlying prosocial decisions, linking personality, emotion, and overt prosocial behavior. Using a multimethod approach, we explored the links between the Big Five dimensions of personality and prosocial responding. Across three studies, we found that agreeableness was the dimension of personality most closely associated with emotional reactions to victims in need of help, and subsequent decisions to help those individuals. Results suggest that prosocial processes, including emotions, cognitions, and behaviors, may be part of a more general motivational process linked to personality. © 2016 by the Society for Personality and Social Psychology, Inc.

  3. Beyond Failure: Potentially Mitigating Failed Author Searches in the Online Library Catalog through the Use of Linked Data

    Science.gov (United States)

    Moulaison, Heather Lea; Stanley, Susan Nicole

    2013-01-01

    Linked data stores house vetted content that can supplement the information available through online library catalogs, potentially mitigating failed author searches if information about the author exists in linked data formats. In this case study, a total of 689 failed author index queries from a large Midwestern academic library's online library…

  4. A simple rain attenuation model for earth-space radio links operating at 10-35 GHz

    Science.gov (United States)

    Stutzman, W. L.; Yon, K. M.

    1986-01-01

    The simple attenuation model has been improved from an earlier version and now includes the effect of wave polarization. The model is for the prediction of rain attenuation statistics on earth-space communication links operating in the 10-35 GHz band. Simple calculations produce attenuation values as a function of average rain rate. These together with rain rate statistics (either measured or predicted) can be used to predict annual rain attenuation statistics. In this paper model predictions are compared to measured data from a data base of 62 experiments performed in the U.S., Europe, and Japan. Comparisons are also made to predictions from other models.

  5. Google Power Search

    CERN Document Server

    Spencer, Stephan

    2011-01-01

    Behind Google's deceptively simple interface is immense power for both market and competitive research-if you know how to use it well. Sure, basic searches are easy, but complex searches require specialized skills. This concise book takes you through the full range of Google's powerful search-refinement features, so you can quickly find the specific information you need. Learn techniques ranging from simple Boolean logic to URL parameters and other advanced tools, and see how they're applied to real-world market research examples. Incorporate advanced search operators such as filetype:, intit

  6. Prospects for SIMPLE 2000: a large-mass, low-background superheated droplet detector for WIMP searches

    International Nuclear Information System (INIS)

    Collar, J.I.; Girard, T.A.; Miley, H.S.; Waysand, G.

    2000-01-01

    The Superheated Instrument for Massive Particle searches (SIMPLE 2000) will consist of an array of 8-16 large active mass (approx. 15 g) superheated droplet detectors (SDDs) to be installed in the new underground laboratory of Rustrel-Pays d'Apt. Several factors make the use of SDDs an attractive approach for the detection of weakly interacting massive particles (WIMPs), namely their intrinsic insensitivity to minimally ionizing particles, high fluorine content, low cost and operation at near ambient pressure and temperature. We comment here on the fabrication, calibration and already-competitive first limits from prototype SDDs for SIMPLE, as well as on the expected immediate increase in sensitivity of the programme, which aims at an exposure of > 25 kg day during 2000. The ability of modest-mass fluorine-rich detectors to investigate regions of neutralino parameter space beyond the reach of the most ambitious cryogenic projects is pointed out. (author)

  7. Prospects for SIMPLE 2000: a large-mass, low-background superheated droplet detector for WIMP searches

    International Nuclear Information System (INIS)

    Collar, J I; Puibasset, J; Girard, T A; Limagne, D; Miley, H S; Waysand, G

    2000-01-01

    The Superheated Instrument for Massive Particle searches (SIMPLE 2000) will consist of an array of 8-16 large active mass (≅15 g) superheated droplet detectors (SDDs) to be installed in the new underground laboratory of Rustrel-Pays d'Apt. Several factors make the use of SDDs an attractive approach for the detection of weakly interacting massive particles (WIMPs), namely their intrinsic insensitivity to minimally ionizing particles, high fluorine content, low cost and operation at near ambient pressure and temperature. We comment here on the fabrication, calibration and already-competitive first limits from prototype SDDs for SIMPLE, as well as on the expected immediate increase in sensitivity of the programme, which aims at an exposure of > 25 kg day during 2000. The ability of modest-mass fluorine-rich detectors to investigate regions of neutralino parameter space beyond the reach of the most ambitious cryogenic projects is pointed out

  8. Search without Boundaries Using Simple APIs

    Science.gov (United States)

    Tong, Qi (Helen)

    2009-01-01

    The U.S. Geological Survey (USGS) Library, where the author serves as the digital services librarian, is increasingly challenged to make it easier for users to find information from many heterogeneous information sources. Information is scattered throughout different software applications (i.e., library catalog, federated search engine, link…

  9. A review of the scientific rationale and methods used in the search for other planetary systems

    Science.gov (United States)

    Black, D. C.

    1985-01-01

    Planetary systems appear to be one of the crucial links in the chain leading from simple molecules to living systems, particularly complex (intelligent?) living systems. Although there is currently no observational proof of the existence of any planetary system other than our own, techniques are now being developed which will permit a comprehensive search for other planetary systems. The scientific rationale for and methods used in such a search effort are reviewed here.

  10. A Simple Time Domain Collocation Method to Precisely Search for the Periodic Orbits of Satellite Relative Motion

    Directory of Open Access Journals (Sweden)

    Xiaokui Yue

    2014-01-01

    Full Text Available A numerical approach for obtaining periodic orbits of satellite relative motion is proposed, based on using the time domain collocation (TDC method to search for the periodic solutions of an exact J2 nonlinear relative model. The initial conditions for periodic relative orbits of the Clohessy-Wiltshire (C-W equations or Tschauner-Hempel (T-H equations can be refined with this approach to generate nearly bounded orbits. With these orbits, a method based on the least-squares principle is then proposed to generate projected closed orbit (PCO, which is a reference for the relative motion control. Numerical simulations reveal that the presented TDC searching scheme is effective and simple, and the projected closed orbit is very fuel saving.

  11. A Framing Link Based Tabu Search Algorithm for Large-Scale Multidepot Vehicle Routing Problems

    Directory of Open Access Journals (Sweden)

    Xuhao Zhang

    2014-01-01

    Full Text Available A framing link (FL based tabu search algorithm is proposed in this paper for a large-scale multidepot vehicle routing problem (LSMDVRP. Framing links are generated during continuous great optimization of current solutions and then taken as skeletons so as to improve optimal seeking ability, speed up the process of optimization, and obtain better results. Based on the comparison between pre- and postmutation routes in the current solution, different parts are extracted. In the current optimization period, links involved in the optimal solution are regarded as candidates to the FL base. Multiple optimization periods exist in the whole algorithm, and there are several potential FLs in each period. If the update condition is satisfied, the FL base is updated, new FLs are added into the current route, and the next period starts. Through adjusting the borderline of multidepot sharing area with dynamic parameters, the authors define candidate selection principles for three kinds of customer connections, respectively. Link split and the roulette approach are employed to choose FLs. 18 LSMDVRP instances in three groups are studied and new optimal solution values for nine of them are obtained, with higher computation speed and reliability.

  12. Prospects for SIMPLE 2000 A large-mass, low-background Superheated Droplet Detector for WIMP searches

    CERN Document Server

    Collar, J I; Girard, T A; Limagne, D; Miley, H S; Waysand, G

    2000-01-01

    SIMPLE 2000 ({\\underline S}uperheated {\\underline I}nstrument for {\\underline M}assive {\\underline P}artic{\\underline {LE}} searches) will consist of an array of eight to sixteen large active mass ($\\sim15$ g) Superheated Droplet Detectors(SDDs) to be installed in the new underground laboratory of Rustrel-Pays d'Apt. Several factors make of SDDs an attractive approach for the detection of Weakly Interacting Massive Particles (WIMPs), namely their intrinsic insensitivity to minimum ionizing particles, high fluorine content, low cost and operation near ambient pressure and temperature. We comment here on the fabrication, calibration and already-competitive first limits from SIMPLE prototype SDDs, as well as on the expected immediate increase in sensitivity of the program, which aims at an exposure of $>$25 kg-day during the year 2000. The ability of modest-mass fluorine-rich detectors to explore regions of neutralino parameter space beyond the reach of the most ambitious cryogenic projects is pointed out.

  13. When is a search not a search? A comparison of searching the AMED complementary health database via EBSCOhost, OVID and DIALOG.

    Science.gov (United States)

    Younger, Paula; Boddy, Kate

    2009-06-01

    The researchers involved in this study work at Exeter Health library and at the Complementary Medicine Unit, Peninsula School of Medicine and Dentistry (PCMD). Within this collaborative environment it is possible to access the electronic resources of three institutions. This includes access to AMED and other databases using different interfaces. The aim of this study was to investigate whether searching different interfaces to the AMED allied health and complementary medicine database produced the same results when using identical search terms. The following Internet-based AMED interfaces were searched: DIALOG DataStar; EBSCOhost and OVID SP_UI01.00.02. Search results from all three databases were saved in an endnote database to facilitate analysis. A checklist was also compiled comparing interface features. In our initial search, DIALOG returned 29 hits, OVID 14 and Ebsco 8. If we assume that DIALOG returned 100% of potential hits, OVID initially returned only 48% of hits and EBSCOhost only 28%. In our search, a researcher using the Ebsco interface to carry out a simple search on AMED would miss over 70% of possible search hits. Subsequent EBSCOhost searches on different subjects failed to find between 21 and 86% of the hits retrieved using the same keywords via DIALOG DataStar. In two cases, the simple EBSCOhost search failed to find any of the results found via DIALOG DataStar. Depending on the interface, the number of hits retrieved from the same database with the same simple search can vary dramatically. Some simple searches fail to retrieve a substantial percentage of citations. This may result in an uninformed literature review, research funding application or treatment intervention. In addition to ensuring that keywords, spelling and medical subject headings (MeSH) accurately reflect the nature of the search, database users should include wildcards and truncation and adapt their search strategy substantially to retrieve the maximum number of appropriate

  14. Cultural differences in attention: Eye movement evidence from a comparative visual search task.

    Science.gov (United States)

    Alotaibi, Albandri; Underwood, Geoffrey; Smith, Alastair D

    2017-10-01

    Individual differences in visual attention have been linked to thinking style: analytic thinking (common in individualistic cultures) is thought to promote attention to detail and focus on the most important part of a scene, whereas holistic thinking (common in collectivist cultures) promotes attention to the global structure of a scene and the relationship between its parts. However, this theory is primarily based on relatively simple judgement tasks. We compared groups from Great Britain (an individualist culture) and Saudi Arabia (a collectivist culture) on a more complex comparative visual search task, using simple natural scenes. A higher overall number of fixations for Saudi participants, along with longer search times, indicated less efficient search behaviour than British participants. Furthermore, intra-group comparisons of scan-path for Saudi participants revealed less similarity than within the British group. Together, these findings suggest that there is a positive relationship between an analytic cognitive style and controlled attention. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Search Parameter Optimization for Discrete, Bayesian, and Continuous Search Algorithms

    Science.gov (United States)

    2017-09-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS SEARCH PARAMETER OPTIMIZATION FOR DISCRETE , BAYESIAN, AND CONTINUOUS SEARCH ALGORITHMS by...to 09-22-2017 4. TITLE AND SUBTITLE SEARCH PARAMETER OPTIMIZATION FOR DISCRETE , BAYESIAN, AND CON- TINUOUS SEARCH ALGORITHMS 5. FUNDING NUMBERS 6...simple search and rescue acts to prosecuting aerial/surface/submersible targets on mission. This research looks at varying the known discrete and

  16. A simple structure wavelet transform circuit employing function link neural networks and SI filters

    Science.gov (United States)

    Mu, Li; Yigang, He

    2016-12-01

    Signal processing by means of analog circuits offers advantages from a power consumption viewpoint. Implementing wavelet transform (WT) using analog circuits is of great interest when low-power consumption becomes an important issue. In this article, a novel simple structure WT circuit in analog domain is presented by employing functional link neural network (FLNN) and switched-current (SI) filters. First, the wavelet base is approximated using FLNN algorithms for giving a filter transfer function that is suitable for simple structure WT circuit implementation. Next, the WT circuit is constructed with the wavelet filter bank, whose impulse response is the approximated wavelet and its dilations. The filter design that follows is based on a follow-the-leader feedback (FLF) structure with multiple output bilinear SI integrators and current mirrors as the main building blocks. SI filter is well suited for this application since the dilation constant across different scales of the transform can be precisely implemented and controlled by the clock frequency of the circuit with the same system architecture. Finally, to illustrate the design procedure, a seventh-order FLNN-approximated Gaussian wavelet is implemented as an example. Simulations have successfully verified that the designed simple structure WT circuit has low sensitivity, low-power consumption and litter effect to the imperfections.

  17. Simple unification

    International Nuclear Information System (INIS)

    Ponce, W.A.; Zepeda, A.

    1987-08-01

    We present the results obtained from our systematic search of a simple Lie group that unifies weak and electromagnetic interactions in a single truly unified theory. We work with fractionally charged quarks, and allow for particles and antiparticles to belong to the same irreducible representation. We found that models based on SU(6), SU(7), SU(8) and SU(10) are viable candidates for simple unification. (author). 23 refs

  18. Registered plant list - PGDBj Registered plant list, Marker list, QTL list, Plant DB link & Genome analysis methods | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available List Contact us PGDBj Registered plant list, Marker list, QTL list, Plant DB link & Genome analysis methods ...the Plant DB link list in simple search page) Genome analysis methods Presence or... absence of Genome analysis methods information in this DB (link to the Genome analysis methods information ...base Site Policy | Contact Us Registered plant list - PGDBj Registered plant list, Marker list, QTL list, Plant DB link & Genome analysis methods | LSDB Archive ...

  19. EarthCube GeoLink: Semantics and Linked Data for the Geosciences

    Science.gov (United States)

    Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Fils, D.; Hitzler, P.; Janowicz, K.; Ji, P.; Jones, M. B.; Krisnadhi, A.; Lehnert, K. A.; Mickle, A.; Narock, T.; O'Brien, M.; Raymond, L. M.; Schildhauer, M.; Shepherd, A.; Wiebe, P. H.

    2015-12-01

    The NSF EarthCube initiative is building next-generation cyberinfrastructure to aid geoscientists in collecting, accessing, analyzing, sharing, and visualizing their data and knowledge. The EarthCube GeoLink Building Block project focuses on a specific set of software protocols and vocabularies, often characterized as the Semantic Web and "Linked Data", to publish data online in a way that is easily discoverable, accessible, and interoperable. GeoLink brings together specialists from the computer science, geoscience, and library science domains, and includes data from a network of NSF-funded repositories that support scientific studies in marine geology, marine ecosystems, biogeochemistry, and paleoclimatology. We are working collaboratively with closely-related Building Block projects including EarthCollab and CINERGI, and solicit feedback from RCN projects including Cyberinfrastructure for Paleogeosciences (C4P) and iSamples. GeoLink has developed a modular ontology that describes essential geoscience research concepts; published data from seven collections (to date) on the Web as geospatially-enabled Linked Data using this ontology; matched and mapped data between collections using shared identifiers for investigators, repositories, datasets, funding awards, platforms, research cruises, physical specimens, and gazetteer features; and aggregated the results in a shared knowledgebase that can be queried via a standard SPARQL endpoint. Client applications have been built around the knowledgebase, including a Web/map-based data browser using the Leaflet JavaScript library and a simple query service using the OpenSearch format. Future development will include extending and refining the GeoLink ontology, adding content from additional repositories, developing semi-automated algorithms to enhance metadata, and further work on client applications.

  20. Linked Metadata - lightweight semantics for data integration (Invited)

    Science.gov (United States)

    Hendler, J. A.

    2013-12-01

    The "Linked Open Data" cloud (http://linkeddata.org) is currently used to show how the linking of datasets, supported by SPARQL endpoints, is creating a growing set of linked data assets. This linked data space has been growing rapidly, and the last version collected is estimated to have had over 35 billion 'triples.' As impressive as this may sound, there is an inherent flaw in the way the linked data story is conceived. The idea is that all of the data is represented in a linked format (generally RDF) and applications will essentially query this cloud and provide mashup capabilities between the various kinds of data that are found. The view of linking in the cloud is fairly simple -links are provided by either shared URIs or by URIs that are asserted to be owl:sameAs. This view of the linking, which primarily focuses on shared objects and subjects in RDF's subject-predicate-object representation, misses a critical aspect of Semantic Web technology. Given triples such as * A:person1 foaf:knows A:person2 * B:person3 foaf:knows B:person4 * C:person5 foaf:name 'John Doe' this view would not consider them linked (barring other assertions) even though they share a common vocabulary. In fact, we get significant clues that there are commonalities in these data items from the shared namespaces and predicates, even if the traditional 'graph' view of RDF doesn't appear to join on these. Thus, it is the linking of the data descriptions, whether as metadata or other vocabularies, that provides the linking in these cases. This observation is crucial to scientific data integration where the size of the datasets, or even the individual relationships within them, can be quite large. (Note that this is not restricted to scientific data - search engines, social networks, and massive multiuser games also create huge amounts of data.) To convert all the triples into RDF and provide individual links is often unnecessary, and is both time and space intensive. Those looking to do on the

  1. A simple heuristic for Internet-based evidence search in primary care: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Eberbach A

    2016-08-01

    Full Text Available Andreas Eberbach,1 Annette Becker,1 Justine Rochon,2 Holger Finkemeler,1Achim Wagner,3 Norbert Donner-Banzhoff1 1Department of Family and Community Medicine, Philipp University of Marburg, Marburg, Germany; 2Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany; 3Department of Sport Medicine, Justus-Liebig-University of Giessen, Giessen, Germany Background: General practitioners (GPs are confronted with a wide variety of clinical questions, many of which remain unanswered. Methods: In order to assist GPs in finding quick, evidence-based answers, we developed a learning program (LP with a short interactive workshop based on a simple ­three-step-heuristic to improve their search and appraisal competence (SAC. We evaluated the LP ­effectiveness with a randomized controlled trial (RCT. Participants (intervention group [IG] n=20; ­control group [CG] n=31 rated acceptance and satisfaction and also answered 39 ­knowledge ­questions to assess their SAC. We controlled for previous knowledge in content areas covered by the test. Results: Main outcome – SAC: within both groups, the pre–post test shows significant (P=0.00 improvements in correctness (IG 15% vs CG 11% and confidence (32% vs 26% to find evidence-based answers. However, the SAC difference was not significant in the RCT. Other measures: Most workshop participants rated “learning atmosphere” (90%, “skills acquired” (90%, and “relevancy to my practice” (86% as good or very good. The ­LP-recommendations were implemented by 67% of the IG, whereas 15% of the CG already conformed to LP recommendations spontaneously (odds ratio 9.6, P=0.00. After literature search, the IG showed a (not significantly higher satisfaction regarding “time spent” (IG 80% vs CG 65%, “quality of information” (65% vs 54%, and “amount of information” (53% vs 47%.Conclusion: Long-standing established GPs have a good SAC. Despite high acceptance, strong

  2. Expectations and experiences of gamete donors and donor-conceived adults searching for genetic relatives using DNA linking through a voluntary register.

    Science.gov (United States)

    van den Akker, O B A; Crawshaw, M A; Blyth, E D; Frith, L J

    2015-01-01

    What are the experiences of donor-conceived adults and donors who are searching for a genetic link through the use of a DNA-based voluntary register service? Donor-conceived adults and donors held positive beliefs about their search and although some concerns in relation to finding a genetically linked relative were reported, these were not a barrier to searching. Research with donor-conceived people has consistently identified their interest in learning about-and in some cases making contact with-their donor and other genetic relatives. However, donor-conceived individuals or donors rarely have the opportunity to act on these desires. A questionnaire was administered for online completion using Bristol Online Surveys. The survey was live for 3 months and responses were collected anonymously. The survey was completed by 65 donor-conceived adults, 21 sperm donors and 5 oocyte donors who had registered with a DNA-based voluntary contact register in the UK. The questionnaire included socio-demographic questions, questions specifically developed for the purposes of this study and the standardized Aspects of Identity Questionnaire (AIQ). Motivations for searching for genetic relatives were varied, with the most common reasons being curiosity and passing on information. Overall, participants who were already linked and those awaiting a link were positive about being linked and valued access to a DNA-based register. Collective identity (reflecting self-defining feelings of continuity and uniqueness), as assessed by the AIQ, was significantly lower for donor-conceived adults when compared with the donor groups (P 0.05) for donor-conceived adults. Participants were members of a UK DNA-based registry which is unique. It was therefore not possible to determine how representative participants were of those who did not register for the service, those in other countries or of those who do not seek information exchange or contact. This is the first survey exploring the

  3. I-SG : Interactive Search Grouping - Search result grouping using Independent Component Analysis

    DEFF Research Database (Denmark)

    Lauritsen, Thomas; Kolenda, Thomas

    2002-01-01

    We present a computational simple and efficient approach to unsupervised grouping the search result from any search engine. Along with each group a set of keywords are found to annotate the contents. This approach leads to an interactive search trough a hierarchial structure that is build online....... It is the users task to improve the search, trough expanding the search query using the topic keywords representing the desired groups. In doing so the search engine limits the space of possible search results, virtually moving down in the search hierarchy, and so refines the search....

  4. Searching low and high

    DEFF Research Database (Denmark)

    Laursen, Keld; Salter, Ammon

    2003-01-01

    AbstractThis paper examines the factors that influence whether firms draw from universities in theirinnovative activities. The link between the universities and industrial innovation, and the role ofdifferent search strategies in influencing the propensity of firms to use universities is explored.......The results suggest that firms who adopt `open' search strategies and invest in R&D are morelikely than other firms to draw from universities, indicating that managerial choice matters inshaping the propensity of firms to draw from universities.Key words: University-industry links, innovation, external search...

  5. Searching for climate-conflict links

    Science.gov (United States)

    Hendrix, Cullen S.

    2018-03-01

    Environmental scarcity caused by climate change has been implicated as a driver of violent conflict. Now, research shows significant bias in the regions analysed for climate-conflict links. This may limit understanding of the socioeconomic and political conditions in which such conflict occurs, and how these conflicts could be prevented.

  6. The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia

    OpenAIRE

    Stanley, Edward C.; Azzinaro, Paul A.; Vierra, David A.; Howlett, Niall G.; Irvine, Steven Q.

    2016-01-01

    Fanconi anemia (FA) is a human genetic disease characterized by congenital defects, bone marrow failure, and increased cancer risk. FA is associated with mutation in one of 24 genes. The protein products of these genes function cooperatively in the FA pathway to orchestrate the repair of DNA interstrand cross-links. Few model organisms exist for the study of FA. Seeking a model organism with a simpler version of the FA pathway, we searched the genome of the simple chordate Ciona intestinalis ...

  7. CrossWork: Software-assisted identification of cross-linked peptides

    DEFF Research Database (Denmark)

    Rasmussen, Morten; Refsgaard, Jan; Peng, Li

    2011-01-01

    Work searches batches of tandem mass-spectrometric data, and identifies cross-linked and non-cross-linked peptides using a standard PC. We tested CrossWork by searching mass-spectrometric datasets of cross-linked complement factor C3 against small (1 protein) and large (1000 proteins) search spaces, and show...

  8. The Usefulness of Leukosan SkinLink for Simple Facial Laceration Repair in the Emergency Department

    Directory of Open Access Journals (Sweden)

    Hyunjoo Kim

    2015-07-01

    Full Text Available BackgroundRepair of facial laceration in the emergency department can pose a number of difficulties. Children can be uncooperative, but adults can also be if they have sustained head trauma or are intoxicated. Leukosan SkinLink consists of topical adhesive and adhesive tape that can be applied easily to long or tense wounds. In this study, the authors compared conventional suturing with Leukosan SkinLink for facial laceration patients in the emergency department.MethodsThe prospective study was carried out from March 2013 to September 2013 with linear facial laceration patients visiting the emergency department. Exclusion criteria were open fractures, joint injuries, skin defects, hairy skin, and mucosa. The author used Leukosan SkinLink for skin closure in the experimental group and used conventional suturing in the control group. The scar evaluation using the Patient and Observer Scar Assessment Scale (POSAS along with satisfaction scores, procedure times, and complications were compared.ResultsA total of 77 patients (30 in the control group and 47 in the experimental group participated and underwent follow-up for 6 months postoperatively. The scar assessment using the POSAS and the satisfaction score in both groups were similar. The average procedure time in the experimental group was shorter. In the control group, there were four cases of wound dehiscence, two of infection, and one of skin necrosis, whereas four cases of wound dehiscence and one allergic reaction occurred in the experimental group.ConclusionsWith a simple application technique, Leukosan SkinLink is a new effective method for facial laceration repair especially useful for children and uncooperative adults.

  9. Development of FPGA-based High Speed Serial Links for High Energy Physics Experiments

    CERN Document Server

    Perrella, Sabrina; Giordano, Raffaele; Izzo, Vincenzo

    Ricerca Simple Search Advanced Search Ultime accessioni Browse Browse by Author Browse by Subject Browse by Year Browse by Type Browse by Accessibilità del full-text Informazioni Policy About FAQ Contatti Perrella, Sabrina (2016) Development of FPGA-based High-Speed serial links for High Energy Physics Experiments. [Tesi di dottorato] [img] Text Perrella_Sabrina_28.pdf Download (59MB) | Preview [error in script] [error in script] Item Type: Tesi di dottorato Lingua: English Title: Development of FPGA-based High-Speed serial links for High Energy Physics Experiments Creators: Creators\tEmail Perrella, Sabrina\tsa.perrella@gmail.com Date: 31 March 2016 Number of Pages: 113 Institution: Università degli Studi di Napoli Federico II Department: Fisica Scuola di dottorato: Scienze fisiche Dottorato: Fisica fondamentale ed applicata Ciclo di dottorato: 28 Coordinatore del Corso di dottorato: nome\temail Velotta, Raffaele\tvelotta@na.infn.it Tutor: nome\temail Alviggi, Mariagrazia\tUNSPECIFIED Giordano, ...

  10. The Evolution of Web Searching.

    Science.gov (United States)

    Green, David

    2000-01-01

    Explores the interrelation between Web publishing and information retrieval technologies and lists new approaches to Web indexing and searching. Highlights include Web directories; search engines; portalisation; Internet service providers; browser providers; meta search engines; popularity based analysis; natural language searching; links-based…

  11. Search for and study of linking transitions between super- and normal deformed wells in the 151Tb nucleus

    International Nuclear Information System (INIS)

    Robin, J.

    2003-12-01

    While the superdeformation phenomenon has been observed many times in different mass regions, the excitation energy and angular momentum are not known for most of the superdeformed bands, mainly in the A ∼ 150 mass region. We have thus undertaken the search for and study of linking transitions between super and normal deformed potential wells in the Tb 151 nucleus with the EUROBALL-IV spectrometer based at the subatomic research institute of Strasbourg. This nucleus presents the peculiarity of having an excited superdeformed band identical to the yrast one of Dy 152 , which has recently been linked to normal deformed states. As the Dy 152 nucleus exhibits a shape coexistence in the first potential well, we have also searched for collective rotational bands with prolate but moderate shape, coexisting with the oblate structure of Tb 151 . The discovery of new superdeformed bands in the Tb 151,152 isotopes, the extension to lower and higher spins of the previously known bands, and mean field calculations with a deformed Woods-Saxon potential have contributed to improve our knowledge as well as raise new questions on the orbitals configuration assignments of these bands. (author)

  12. Search times and probability of detection in time-limited search

    Science.gov (United States)

    Wilson, David; Devitt, Nicole; Maurer, Tana

    2005-05-01

    When modeling the search and target acquisition process, probability of detection as a function of time is important to war games and physical entity simulations. Recent US Army RDECOM CERDEC Night Vision and Electronics Sensor Directorate modeling of search and detection has focused on time-limited search. Developing the relationship between detection probability and time of search as a differential equation is explored. One of the parameters in the current formula for probability of detection in time-limited search corresponds to the mean time to detect in time-unlimited search. However, the mean time to detect in time-limited search is shorter than the mean time to detect in time-unlimited search and the relationship between them is a mathematical relationship between these two mean times. This simple relationship is derived.

  13. Radioastronomical Searches for Instellar Biomolecules

    Science.gov (United States)

    Kuan, Y.-J.; Huang, H.-C.; Charnley, S. B.; Markwick, A.; Botta, O.; Ehrenfreund, P.; Kisiel, Z.; Butner, H. M.

    2003-01-01

    Impacts of comets and asteroids could have delivered large amounts of organic matter to the early Earth. to retain a significant interstellar signature; observations of recent bright comets indicate that they have a molecular inventory consistent with their ices being largely unmodified interstellar material. Many simple organic molecules with biochemical significance observed in circumstellar envelopes and in molecular clouds, similar to that from which the Solar System formed, may have acted as the precursors of the more complex organics found in meteorites. Therefore, there is potentially a strong link between interstellar organics and prebiotic chemical evolution. Radioastronomical observations, particularly at millimeter wavelengths, allow us to determine the chemical composition and characteristics of the molecular inventory in interstellar space. Here we report some of our recent results from extensive astronomical searches for astrobiologically-important interstellar organics.

  14. The search image as link between sensation, perception and action.

    Science.gov (United States)

    Tønnessen, Morten

    2018-02-01

    In this paper, it is argued that Jakob von Uexküll's "search image" notion, the original version of this notion within ethology, is still of use. A search image, in Uexküll's sense, is an imagined object that an organism has in mind when it searches for something. Uexküll's conception of the search image is useful both for understanding the theoretical context of contemporary notions of search images, and with an eye to envisioning possible future developments of the idea. Uexküll's classical notion differs from contemporary versions in that it has a wider application, and is therefore of greater relevance to theoretical biology and cognitive science. It constituted an integral part of his ground-breaking Umwelt theory, stressing the fundamental plasticity of the Umwelt, the subjective lifeworld of an animal or human subject. In a contemporary development of Umwelt theory, expressed by the tripartite Umwelt model, the search image notion represents a key connection between the directly experienced core Umwelt and the mediated Umwelt. However, the key function that schemata have in cognitive processes is also the starting point for mistakes in perception. This article details both the constructive function search images have in animal and human perception, and the mismatches in perception they can lead to. It also explains how the existence of search images can help explain puzzles concerning subjective and neural time in contemporary cognitive science. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Keyword Search in Databases

    CERN Document Server

    Yu, Jeffrey Xu; Chang, Lijun

    2009-01-01

    It has become highly desirable to provide users with flexible ways to query/search information over databases as simple as keyword search like Google search. This book surveys the recent developments on keyword search over databases, and focuses on finding structural information among objects in a database using a set of keywords. Such structural information to be returned can be either trees or subgraphs representing how the objects, that contain the required keywords, are interconnected in a relational database or in an XML database. The structural keyword search is completely different from

  16. Semantic search: finding KTBL's planning data and reusing them in IT systems

    Directory of Open Access Journals (Sweden)

    Daniel Martini

    2014-02-01

    Full Text Available The effort to investigate relevant data for planning purposes and preparation of labour and investments in agricultural production as well as reworking and entering them for reuse in calculation tools and farm management information systems are major challenges for decisions based on data. The following paper presents a solution which on the one hand simplifies targeted finding of planning data within KTBL’s data sets using a semantic search engine and on the other hand enables simple reuse and processing of these data by providing them using Linked Open Data principles.

  17. Automatic and directed search processes in solving simple semantic-memory problems.

    Science.gov (United States)

    Ben-Zur, H

    1989-09-01

    The cognitive processes involved in simple semantic-memory problems were investigated in four experiments. On each trial of Experiments 1 and 2, two stimulus words were presented, with the instructions to find a third word (i.e., the solution) that, when coupled with each of the stimuli, would yield two word pairs used in everyday language (e.g., surprise and birthday, for which the solution is party). The results of the two experiments indicated that informing the subject whether the solution constituted the first or the second element in the word pairs facilitated both likelihood and speed of solution attainment. In addition, solution attainment was relatively high for items based on frequently used word pairs (Experiment 1) and for items in which the stimuli appear, in everyday language, in a small number of word pairs (Experiment 2). In Experiment 3, the subjects were required to produce word pairs containing one of the two stimulus words from the items used in Experiment 2. Solution production was facilitated by rehearsing the second stimulus word of the specific item. The conclusion, supported by a post hoc analysis of the results of Experiments 2 and 3 (Experiment 4), was that indirect priming from one stimulus word may facilitate solution production from a searched word. These results are interpreted in terms of automatic and controlled processes, and their relevance to two different models for retrieval from semantic memory is discussed.

  18. Search of the Deep and Dark Web via DARPA Memex

    Science.gov (United States)

    Mattmann, C. A.

    2015-12-01

    Search has progressed through several stages due to the increasing size of the Web. Search engines first focused on text and its rate of occurrence; then focused on the notion of link analysis and citation then on interactivity and guided search; and now on the use of social media - who we interact with, what we comment on, and who we follow (and who follows us). The next stage, referred to as "deep search," requires solutions that can bring together text, images, video, importance, interactivity, and social media to solve this challenging problem. The Apache Nutch project provides an open framework for large-scale, targeted, vertical search with capabilities to support all past and potential future search engine foci. Nutch is a flexible infrastructure allowing open access to ranking; URL selection and filtering approaches, to the link graph generated from search, and Nutch has spawned entire sub communities including Apache Hadoop and Apache Tika. It addresses many current needs with the capability to support new technologies such as image and video. On the DARPA Memex project, we are creating create specific extensions to Nutch that will directly improve its overall technological superiority for search and that will directly allow us to address complex search problems including human trafficking. We are integrating state-of-the-art algorithms developed by Kitware for IARPA Aladdin combined with work by Harvard to provide image and video understanding support allowing automatic detection of people and things and massive deployment via Nutch. We are expanding Apache Tika for scene understanding, object/person detection and classification in images/video. We are delivering an interactive and visual interface for initiating Nutch crawls. The interface uses Python technologies to expose Nutch data and to provide a domain specific language for crawls. With the Bokeh visualization library the interface we are delivering simple interactive crawl visualization and

  19. Evidence-based Medicine Search: a customizable federated search engine.

    Science.gov (United States)

    Bracke, Paul J; Howse, David K; Keim, Samuel M

    2008-04-01

    This paper reports on the development of a tool by the Arizona Health Sciences Library (AHSL) for searching clinical evidence that can be customized for different user groups. The AHSL provides services to the University of Arizona's (UA's) health sciences programs and to the University Medical Center. Librarians at AHSL collaborated with UA College of Medicine faculty to create an innovative search engine, Evidence-based Medicine (EBM) Search, that provides users with a simple search interface to EBM resources and presents results organized according to an evidence pyramid. EBM Search was developed with a web-based configuration component that allows the tool to be customized for different specialties. Informal and anecdotal feedback from physicians indicates that EBM Search is a useful tool with potential in teaching evidence-based decision making. While formal evaluation is still being planned, a tool such as EBM Search, which can be configured for specific user populations, may help lower barriers to information resources in an academic health sciences center.

  20. LOTUS: Adaptive text search for big linked data

    NARCIS (Netherlands)

    Ilievski, F.; Beek, Wouter; van Erp, Marieke; Rietveld, Laurens; Schlobach, Stefan

    2016-01-01

    Finding relevant resources on the Semantic Web today is a dirty job: no centralized query service exists and the support for natural language access is limited. We present LOTUS: Linked Open Text Un- leaShed, a text-based entry point to a massive subset of today’s Linked Open Data Cloud. Recognizing

  1. Visual Representation Determines Search Difficulty: Explaining Visual Search Asymmetries

    Directory of Open Access Journals (Sweden)

    Neil eBruce

    2011-07-01

    Full Text Available In visual search experiments there exist a variety of experimental paradigms in which a symmetric set of experimental conditions yields asymmetric corresponding task performance. There are a variety of examples of this that currently lack a satisfactory explanation. In this paper, we demonstrate that distinct classes of asymmetries may be explained by virtue of a few simple conditions that are consistent with current thinking surrounding computational modeling of visual search and coding in the primate brain. This includes a detailed look at the role that stimulus familiarity plays in the determination of search performance. Overall, we demonstrate that all of these asymmetries have a common origin, namely, they are a consequence of the encoding that appears in the visual cortex. The analysis associated with these cases yields insight into the problem of visual search in general and predictions of novel search asymmetries.

  2. World Wide Web Metaphors for Search Mission Data

    Science.gov (United States)

    Norris, Jeffrey S.; Wallick, Michael N.; Joswig, Joseph C.; Powell, Mark W.; Torres, Recaredo J.; Mittman, David S.; Abramyan, Lucy; Crockett, Thomas M.; Shams, Khawaja S.; Fox, Jason M.; hide

    2010-01-01

    A software program that searches and browses mission data emulates a Web browser, containing standard meta - phors for Web browsing. By taking advantage of back-end URLs, users may save and share search states. Also, since a Web interface is familiar to users, training time is reduced. Familiar back and forward buttons move through a local search history. A refresh/reload button regenerates a query, and loads in any new data. URLs can be constructed to save search results. Adding context to the current search is also handled through a familiar Web metaphor. The query is constructed by clicking on hyperlinks that represent new components to the search query. The selection of a link appears to the user as a page change; the choice of links changes to represent the updated search and the results are filtered by the new criteria. Selecting a navigation link changes the current query and also the URL that is associated with it. The back button can be used to return to the previous search state. This software is part of the MSLICE release, which was written in Java. It will run on any current Windows, Macintosh, or Linux system.

  3. Decoherence in optimized quantum random-walk search algorithm

    International Nuclear Information System (INIS)

    Zhang Yu-Chao; Bao Wan-Su; Wang Xiang; Fu Xiang-Qun

    2015-01-01

    This paper investigates the effects of decoherence generated by broken-link-type noise in the hypercube on an optimized quantum random-walk search algorithm. When the hypercube occurs with random broken links, the optimized quantum random-walk search algorithm with decoherence is depicted through defining the shift operator which includes the possibility of broken links. For a given database size, we obtain the maximum success rate of the algorithm and the required number of iterations through numerical simulations and analysis when the algorithm is in the presence of decoherence. Then the computational complexity of the algorithm with decoherence is obtained. The results show that the ultimate effect of broken-link-type decoherence on the optimized quantum random-walk search algorithm is negative. (paper)

  4. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr ... Populations Treatment Trends & Statistics Women and Drugs Publications Search Publications Orderable DrugFacts Research Reports Mind Over Matter ...

  5. Task relevance of emotional information affects anxiety-linked attention bias in visual search.

    Science.gov (United States)

    Dodd, Helen F; Vogt, Julia; Turkileri, Nilgun; Notebaert, Lies

    2017-01-01

    Task relevance affects emotional attention in healthy individuals. Here, we investigate whether the association between anxiety and attention bias is affected by the task relevance of emotion during an attention task. Participants completed two visual search tasks. In the emotion-irrelevant task, participants were asked to indicate whether a discrepant face in a crowd of neutral, middle-aged faces was old or young. Irrelevant to the task, target faces displayed angry, happy, or neutral expressions. In the emotion-relevant task, participants were asked to indicate whether a discrepant face in a crowd of middle-aged neutral faces was happy or angry (target faces also varied in age). Trait anxiety was not associated with attention in the emotion-relevant task. However, in the emotion-irrelevant task, trait anxiety was associated with a bias for angry over happy faces. These findings demonstrate that the task relevance of emotional information affects conclusions about the presence of an anxiety-linked attention bias. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Mobile Search and Advertising

    OpenAIRE

    Lovitskii, Vladimir; McCaffery, Colin; Thrasher, Michael; Traynor, David; Wright, Peter

    2009-01-01

    Mobile advertising is a rapidly growing sector providing brands and marketing agencies the opportunity to connect with consumers beyond traditional and digital media and instead communicate directly on their mobile phones. Mobile advertising will be intrinsically linked with mobile search, which has transported from the internet to the mobile and is identified as an area of potential growth. The result of mobile searching show that as a general rule such search result exceed 1...

  7. Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures.

    Science.gov (United States)

    Li, Guo-Zhong; Vissers, Johannes P C; Silva, Jeffrey C; Golick, Dan; Gorenstein, Marc V; Geromanos, Scott J

    2009-03-01

    A novel database search algorithm is presented for the qualitative identification of proteins over a wide dynamic range, both in simple and complex biological samples. The algorithm has been designed for the analysis of data originating from data independent acquisitions, whereby multiple precursor ions are fragmented simultaneously. Measurements used by the algorithm include retention time, ion intensities, charge state, and accurate masses on both precursor and product ions from LC-MS data. The search algorithm uses an iterative process whereby each iteration incrementally increases the selectivity, specificity, and sensitivity of the overall strategy. Increased specificity is obtained by utilizing a subset database search approach, whereby for each subsequent stage of the search, only those peptides from securely identified proteins are queried. Tentative peptide and protein identifications are ranked and scored by their relative correlation to a number of models of known and empirically derived physicochemical attributes of proteins and peptides. In addition, the algorithm utilizes decoy database techniques for automatically determining the false positive identification rates. The search algorithm has been tested by comparing the search results from a four-protein mixture, the same four-protein mixture spiked into a complex biological background, and a variety of other "system" type protein digest mixtures. The method was validated independently by data dependent methods, while concurrently relying on replication and selectivity. Comparisons were also performed with other commercially and publicly available peptide fragmentation search algorithms. The presented results demonstrate the ability to correctly identify peptides and proteins from data independent acquisition strategies with high sensitivity and specificity. They also illustrate a more comprehensive analysis of the samples studied; providing approximately 20% more protein identifications, compared to

  8. The impact of PICO as a search strategy tool on literature search quality

    DEFF Research Database (Denmark)

    Eriksen, Mette Brandt; Frandsen, Tove Faber

    2018-01-01

    Objective: This review aimed to determine, if the use of the PICO model (Patient Intervention Comparison Outcome) as a search strategy tool affects the quality of the literature search. Methods: A comprehensive literature search was conducted in: PubMed, Embase, CINAHL, PsycInfo, Cochrane Library...... and three studies were included, data was extracted, risk of bias was assessed and a qualitative analysis was conducted. The included studies compared PICO to PIC or link to related articles in PubMed; PICOS and SPIDER. One study compared PICO to unguided searching. Due to differences in intervention...

  9. Linking Simple Economic Theory Models and the Cointegrated Vector AutoRegressive Model

    DEFF Research Database (Denmark)

    Møller, Niels Framroze

    This paper attempts to clarify the connection between simple economic theory models and the approach of the Cointegrated Vector-Auto-Regressive model (CVAR). By considering (stylized) examples of simple static equilibrium models, it is illustrated in detail, how the theoretical model and its stru....... Further fundamental extensions and advances to more sophisticated theory models, such as those related to dynamics and expectations (in the structural relations) are left for future papers......This paper attempts to clarify the connection between simple economic theory models and the approach of the Cointegrated Vector-Auto-Regressive model (CVAR). By considering (stylized) examples of simple static equilibrium models, it is illustrated in detail, how the theoretical model and its......, it is demonstrated how other controversial hypotheses such as Rational Expectations can be formulated directly as restrictions on the CVAR-parameters. A simple example of a "Neoclassical synthetic" AS-AD model is also formulated. Finally, the partial- general equilibrium distinction is related to the CVAR as well...

  10. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse ... Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with drug misuse are ...

  11. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs ... HIV Learn the Link - Drugs and HIV Email Facebook Twitter 2005 –Ongoing Behaviors associated with drug misuse ...

  12. Real-Time Search in Clouds

    OpenAIRE

    Uddin, Misbah; Skinner, Amy; Stadler, Rolf; Clemm, Alexander

    2013-01-01

    We developed a novel approach for management of networks/networked systems based on network search [4]. Network search provides a simple, uniform interface, through which human administrators and management applications can obtain network information, configuration or operational, without knowing its schema and location. We believe that the capability of network search will spur the development of new tools for human administrators and enable the rapid development of new classes of network co...

  13. Realistic searches on stretched exponential networks

    Indian Academy of Sciences (India)

    We consider navigation or search schemes on networks which have a degree distribution of the form () ∝ exp(−). In addition, the linking probability is taken to be dependent on social distances and is governed by a parameter . The searches are realistic in the sense that not all search chains can be completed.

  14. Optimising mobile phase composition, its flow-rate and column temperature in HPLC using taboo search.

    Science.gov (United States)

    Guillaume, Y C; Peyrin, E

    2000-03-06

    A chemometric methodology is proposed to study the separation of seven p-hydroxybenzoic esters in reversed phase liquid chromatography (RPLC). Fifteen experiments were found to be necessary to find a mathematical model which linked a novel chromatographic response function (CRF) with the column temperature, the water fraction in the mobile phase and its flow rate. The CRF optimum was determined using a new algorithm based on Glover's taboo search (TS). A flow-rate of 0.9 ml min(-1) with a water fraction of 0.64 in the ACN-water mixture and a column temperature of 10 degrees C gave the most efficient separation conditions. The usefulness of TS was compared with the pure random search (PRS) and simplex search (SS). As demonstrated by calculations, the algorithm avoids entrapment in local minima and continues the search to give a near-optimal final solution. Unlike other methods of global optimisation, this procedure is generally applicable, easy to implement, derivative free, conceptually simple and could be used in the future for much more complex optimisation problems.

  15. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse Commonly Abused Drugs Charts Emerging ... Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - ...

  16. Overview of the CLEF 2015 Social Book Search Lab

    DEFF Research Database (Denmark)

    Koolen, Marijn; Bogers, Toine; Gäde, Maria

    2015-01-01

    The Social Book Search (SBS) Lab investigates book search in scenarios where users search with more than just a query, and look for more than objective metadata. Real-world information needs are generally complex, yet almost all research focuses instead on either relatively simple search based on...

  17. Disbiome database: linking the microbiome to disease.

    Science.gov (United States)

    Janssens, Yorick; Nielandt, Joachim; Bronselaer, Antoon; Debunne, Nathan; Verbeke, Frederick; Wynendaele, Evelien; Van Immerseel, Filip; Vandewynckel, Yves-Paul; De Tré, Guy; De Spiegeleer, Bart

    2018-06-04

    Recent research has provided fascinating indications and evidence that the host health is linked to its microbial inhabitants. Due to the development of high-throughput sequencing technologies, more and more data covering microbial composition changes in different disease types are emerging. However, this information is dispersed over a wide variety of medical and biomedical disciplines. Disbiome is a database which collects and presents published microbiota-disease information in a standardized way. The diseases are classified using the MedDRA classification system and the micro-organisms are linked to their NCBI and SILVA taxonomy. Finally, each study included in the Disbiome database is assessed for its reporting quality using a standardized questionnaire. Disbiome is the first database giving a clear, concise and up-to-date overview of microbial composition differences in diseases, together with the relevant information of the studies published. The strength of this database lies within the combination of the presence of references to other databases, which enables both specific and diverse search strategies within the Disbiome database, and the human annotation which ensures a simple and structured presentation of the available data.

  18. Simple PCR assays improve the sensitivity of HIV-1 subtype B drug resistance testing and allow linking of resistance mutations.

    Directory of Open Access Journals (Sweden)

    Jeffrey A Johnson

    Full Text Available BACKGROUND: The success of antiretroviral therapy is known to be compromised by drug-resistant HIV-1 at frequencies detectable by conventional bulk sequencing. Currently, there is a need to assess the clinical consequences of low-frequency drug resistant variants occurring below the detection limit of conventional genotyping. Sensitive detection of drug-resistant subpopulations, however, requires simple and practical methods for routine testing. METHODOLOGY: We developed highly-sensitive and simple real-time PCR assays for nine key drug resistance mutations and show that these tests overcome substantial sequence heterogeneity in HIV-1 clinical specimens. We specifically used early wildtype virus samples from the pre-antiretroviral drug era to measure background reactivity and were able to define highly-specific screening cut-offs that are up to 67-fold more sensitive than conventional genotyping. We also demonstrate that sequencing the mutation-specific PCR products provided a direct and novel strategy to further detect and link associated resistance mutations, allowing easy identification of multi-drug-resistant variants. Resistance mutation associations revealed in mutation-specific amplicon sequences were verified by clonal sequencing. SIGNIFICANCE: Combined, sensitive real-time PCR testing and mutation-specific amplicon sequencing provides a powerful and simple approach that allows for improved detection and evaluation of HIV-1 drug resistance mutations.

  19. Experience of Developing a Meta-Semantic Search Engine

    OpenAIRE

    Mukhopadhyay, Debajyoti; Sharma, Manoj; Joshi, Gajanan; Pagare, Trupti; Palwe, Adarsha

    2013-01-01

    Thinking of todays web search scenario which is mainly keyword based, leads to the need of effective and meaningful search provided by Semantic Web. Existing search engines are vulnerable to provide relevant answers to users query due to their dependency on simple data available in web pages. On other hand, semantic search engines provide efficient and relevant results as the semantic web manages information with well defined meaning using ontology. A Meta-Search engine is a search tool that ...

  20. Person perception informs understanding of cognition during visual search.

    Science.gov (United States)

    Brennan, Allison A; Watson, Marcus R; Kingstone, Alan; Enns, James T

    2011-08-01

    Does person perception--the impressions we form from watching others--hold clues to the mental states of people engaged in cognitive tasks? We investigated this with a two-phase method: In Phase 1, participants searched on a computer screen (Experiment 1) or in an office (Experiment 2); in Phase 2, other participants rated the searchers' video-recorded behavior. The results showed that blind raters are sensitive to individual differences in search proficiency and search strategy, as well as to environmental factors affecting search difficulty. Also, different behaviors were linked to search success in each setting: Eye movement frequency predicted successful search on a computer screen; head movement frequency predicted search success in an office. In both settings, an active search strategy and positive emotional expressions were linked to search success. These data indicate that person perception informs cognition beyond the scope of performance measures, offering the potential for new measurements of cognition that are both rich and unobtrusive.

  1. Test of a potential link between analytic and nonanalytic category learning and automatic, effortful processing.

    Science.gov (United States)

    Tracy, J I; Pinsk, M; Helverson, J; Urban, G; Dietz, T; Smith, D J

    2001-08-01

    The link between automatic and effortful processing and nonanalytic and analytic category learning was evaluated in a sample of 29 college undergraduates using declarative memory, semantic category search, and pseudoword categorization tasks. Automatic and effortful processing measures were hypothesized to be associated with nonanalytic and analytic categorization, respectively. Results suggested that contrary to prediction strong criterion-attribute (analytic) responding on the pseudoword categorization task was associated with strong automatic, implicit memory encoding of frequency-of-occurrence information. Data are discussed in terms of the possibility that criterion-attribute category knowledge, once established, may be expressed with few attentional resources. The data indicate that attention resource requirements, even for the same stimuli and task, vary depending on the category rule system utilized. Also, the automaticity emerging from familiarity with analytic category exemplars is very different from the automaticity arising from extensive practice on a semantic category search task. The data do not support any simple mapping of analytic and nonanalytic forms of category learning onto the automatic and effortful processing dichotomy and challenge simple models of brain asymmetries for such procedures. Copyright 2001 Academic Press.

  2. Ultimate guide to LinkedIn for business

    CERN Document Server

    Prodromou, Ted; Malinchak, James

    2015-01-01

    How To Get Connected with More than 300 Million Customers This popular title delivers an in-depth guide to targeting, reaching, and gaining ideal customers using the latest updates on LinkedIn. LinkedIn expert Ted Prodromou offers a wealth of no- or low-cost methods for maximizing this dynamic resource. Following his lead, readers learn to link with the most effective connections for greater exposure. Updates in this edition include: Staying up-to-date with LinkedIn Contacts, Pulse, and Publisher programs Expansion of premium accounts to help optimize business profiles, stand out in search results, and track impact How to implement new features like Showcase and Company Updates pages for extended presence in newsfeeds and with followers Smarter LinkedIn Search that saves time and money with customized, comprehensive results Other important topics covered include: Techniques and tips to easily navigate LinkedIn's interface Time saving tips on finding and matching data from businesses and people Expert guidance...

  3. A Taxonomic Search Engine: federating taxonomic databases using web services.

    Science.gov (United States)

    Page, Roderic D M

    2005-03-09

    The taxonomic name of an organism is a key link between different databases that store information on that organism. However, in the absence of a single, comprehensive database of organism names, individual databases lack an easy means of checking the correctness of a name. Furthermore, the same organism may have more than one name, and the same name may apply to more than one organism. The Taxonomic Search Engine (TSE) is a web application written in PHP that queries multiple taxonomic databases (ITIS, Index Fungorum, IPNI, NCBI, and uBIO) and summarises the results in a consistent format. It supports "drill-down" queries to retrieve a specific record. The TSE can optionally suggest alternative spellings the user can try. It also acts as a Life Science Identifier (LSID) authority for the source taxonomic databases, providing globally unique identifiers (and associated metadata) for each name. The Taxonomic Search Engine is available at http://darwin.zoology.gla.ac.uk/~rpage/portal/ and provides a simple demonstration of the potential of the federated approach to providing access to taxonomic names.

  4. LINKS to NATIONAL WEATHER SERVICE MARINE FORECAST OFFICES

    Science.gov (United States)

    ; Organization Search Search Landlubber's forecast: "City, St" or zip code (Pan/Zoom for Marine) Search SERVICE MARINE FORECAST OFFICES (Click on the NWS Forecast Center/Office of interest to link to that Marine Forecasts in text form ) Coastal NWS Forecast Offices have regionally focused marine webpages

  5. Persistent Identifiers for Improved Accessibility for Linked Data Querying

    Science.gov (United States)

    Shepherd, A.; Chandler, C. L.; Arko, R. A.; Fils, D.; Jones, M. B.; Krisnadhi, A.; Mecum, B.

    2016-12-01

    The adoption of linked open data principles within the geosciences has increased the amount of accessible information available on the Web. However, this data is difficult to consume for those who are unfamiliar with Semantic Web technologies such as Web Ontology Language (OWL), Resource Description Framework (RDF) and SPARQL - the RDF query language. Consumers would need to understand the structure of the data and how to efficiently query it. Furthermore, understanding how to query doesn't solve problems of poor precision and recall in search results. For consumers unfamiliar with the data, full-text searches are most accessible, but not ideal as they arrest the advantages of data disambiguation and co-reference resolution efforts. Conversely, URI searches across linked data can deliver improved search results, but knowledge of these exact URIs may remain difficult to obtain. The increased adoption of Persistent Identifiers (PIDs) can lead to improved linked data querying by a wide variety of consumers. Because PIDs resolve to a single entity, they are an excellent data point for disambiguating content. At the same time, PIDs are more accessible and prominent than a single data provider's linked data URI. When present in linked open datasets, PIDs provide balance between the technical and social hurdles of linked data querying as evidenced by the NSF EarthCube GeoLink project. The GeoLink project, funded by NSF's EarthCube initiative, have brought together data repositories include content from field expeditions, laboratory analyses, journal publications, conference presentations, theses/reports, and funding awards that span scientific studies from marine geology to marine ecosystems and biogeochemistry to paleoclimatology.

  6. Modernizing quantum annealing using local searches

    International Nuclear Information System (INIS)

    Chancellor, Nicholas

    2017-01-01

    I describe how real quantum annealers may be used to perform local (in state space) searches around specified states, rather than the global searches traditionally implemented in the quantum annealing algorithm (QAA). Such protocols will have numerous advantages over simple quantum annealing. By using such searches the effect of problem mis-specification can be reduced, as only energy differences between the searched states will be relevant. The QAA is an analogue of simulated annealing, a classical numerical technique which has now been superseded. Hence, I explore two strategies to use an annealer in a way which takes advantage of modern classical optimization algorithms. Specifically, I show how sequential calls to quantum annealers can be used to construct analogues of population annealing and parallel tempering which use quantum searches as subroutines. The techniques given here can be applied not only to optimization, but also to sampling. I examine the feasibility of these protocols on real devices and note that implementing such protocols should require minimal if any change to the current design of the flux qubit-based annealers by D-Wave Systems Inc. I further provide proof-of-principle numerical experiments based on quantum Monte Carlo that demonstrate simple examples of the discussed techniques. (paper)

  7. LinkED: A Novel Methodology for Publishing Linked Enterprise Data

    Directory of Open Access Journals (Sweden)

    Shreyas Suresh Rao

    2017-01-01

    Full Text Available Semantic Web technologies have redefined and strengthened the Enterprise-Web interoperability over the last decade. Linked Open Data (LOD refers to a set of best practices that empower enterprises to publish and interlink their data using existing ontologies on the World Wide Web. Current research in LOD focuses on expert search, the creation of unified information space and augmentation of core data from an enterprise context. However, existing approaches for publication of enterprise data as LOD are domain-specific, ad-hoc and suffer from lack of uniform representation across domains. The paper proposes a novel methodology called LinkED that contributes towards LOD literature in two ways: (a streamlines the publishing process through five stages of cleaning, triplification, interlinking, storage and visualization; (b addresses the latest challenges in LOD publication, namely: inadequate links, inconsistencies in the quality of the dataset and replicability of the LOD publication process. Further, the methodology is demonstrated via the publication of digital repository data as LOD in a university setting, which is evaluated based on two semantic standards: Five-Star model and data quality metrics. Overall, the paper provides a generic LOD publication process that is applicable across various domains such as healthcare, e-governance, banking, and tourism, to name a few.

  8. Second Workshop on Supporting Complex Search Tasks

    NARCIS (Netherlands)

    Belkin, Nicholas J.; Bogers, Toine; Kamps, Jaap; Kelly, Diane; Koolen, Marijn; Yilmaz, Emine

    2017-01-01

    There is broad consensus in the field of IR that search is complex in many use cases and applications, both on the Web and in domain specific collections, and both professionally and in our daily life. Yet our understanding of complex search tasks, in comparison to simple look up tasks, is

  9. a Task-Driven Disaster Data Link Approach

    Science.gov (United States)

    Qiu, L. Y.; Zhu, Q.; Gu, J. Y.; Du, Z. Q.

    2015-08-01

    With the rapid development of sensor networks and Earth observation technology, a large quantity of disaster-related data is available, such as remotely sensed data, historic data, cases data, simulation data, disaster products and so on. However, the efficiency of current data management and service systems has become increasingly serious due to the task variety and heterogeneous data. For emergency task-oriented applications, data searching mainly relies on artificial experience based on simple metadata index, whose high time-consuming and low accuracy cannot satisfy the requirements of disaster products on velocity and veracity. In this paper, a task-oriented linking method is proposed for efficient disaster data management and intelligent service, with the objectives of 1) putting forward ontologies of disaster task and data to unify the different semantics of multi-source information, 2) identifying the semantic mapping from emergency tasks to multiple sources on the basis of uniform description in 1), 3) linking task-related data automatically and calculating the degree of correlation between each data and a target task. The method breaks through traditional static management of disaster data and establishes a base for intelligent retrieval and active push of disaster information. The case study presented in this paper illustrates the use of the method with a flood emergency relief task.

  10. Research Proposal for Distributed Deep Web Search

    NARCIS (Netherlands)

    Tjin-Kam-Jet, Kien

    2010-01-01

    This proposal identifies two main problems related to deep web search, and proposes a step by step solution for each of them. The first problem is about searching deep web content by means of a simple free-text interface (with just one input field, instead of a complex interface with many input

  11. The Use of Web Search Engines in Information Science Research.

    Science.gov (United States)

    Bar-Ilan, Judit

    2004-01-01

    Reviews the literature on the use of Web search engines in information science research, including: ways users interact with Web search engines; social aspects of searching; structure and dynamic nature of the Web; link analysis; other bibliometric applications; characterizing information on the Web; search engine evaluation and improvement; and…

  12. An Enhanced Differential Evolution with Elite Chaotic Local Search

    Directory of Open Access Journals (Sweden)

    Zhaolu Guo

    2015-01-01

    Full Text Available Differential evolution (DE is a simple yet efficient evolutionary algorithm for real-world engineering problems. However, its search ability should be further enhanced to obtain better solutions when DE is applied to solve complex optimization problems. This paper presents an enhanced differential evolution with elite chaotic local search (DEECL. In DEECL, it utilizes a chaotic search strategy based on the heuristic information from the elite individuals to promote the exploitation power. Moreover, DEECL employs a simple and effective parameter adaptation mechanism to enhance the robustness. Experiments are conducted on a set of classical test functions. The experimental results show that DEECL is very competitive on the majority of the test functions.

  13. S-LINK, a data link interface specification for the LHC era

    International Nuclear Information System (INIS)

    Bij, H.C. van der; McLaren, R.A.; Boyle, O.

    1996-01-01

    In the Technical Proposals for ATLAS, CMS and ALICE there is a requirement for several thousand data links. Although there is an obvious need for standardization, this seems difficult to achieve as the links run at different speeds, over different distances and have various constraints of power consumption, size and radiation hardness. An additional complication is that today we cannot decide which will be the most cost effective technology for the implementation of the final links. Furthermore, we must allow designers of boards at each end of the link, for example readout electronics and input buffers, to work in parallel with the development of the links. The S-LINK is a new concept which should provide the benefits of standardization without the limitations. The S-LINK specification defines, at both ends of the link, a simple FIFO-like user interface which remains independent of the technology used to implement the physical link. The physical link provides transfer of event data and control words, error detection, optional flow control and test facilities. This paper describes the S-LINK specification and gives examples of the use of the S-LINK, the physical links being designed, and the test equipment that is being developed

  14. List search hardware for interpretive software

    CERN Document Server

    Altaber, Jacques; Mears, B; Rausch, R

    1979-01-01

    Interpreted languages, e.g. BASIC, are simple to learn, easy to use, quick to modify and in general 'user-friendly'. However, a critically time consuming process during interpretation is that of list searching. A special microprogrammed device for fast list searching has therefore been developed at the SPS Division of CERN. It uses bit- sliced hardware. Fast algorithms perform search, insert and delete of a six-character name and its value in a list of up to 1000 pairs. The prototype shows retrieval times of the order of 10-30 microseconds. (11 refs).

  15. Using collaborative filtering in social book search

    NARCIS (Netherlands)

    Huurdeman, H.; Kamps, J.; Koolen, M.; van Wees, J.

    2012-01-01

    In this paper we describe our participation in INEX 2012 in the Social Book Search Track and the Linked Data Track. For the Social Book Search Track we compare the impact of query- and user-independent popularity measures and recommendations based on user profiles. Book suggestions are more than

  16. Short-term Internet search using makes people rely on search engines when facing unknown issues.

    Science.gov (United States)

    Wang, Yifan; Wu, Lingdan; Luo, Liang; Zhang, Yifen; Dong, Guangheng

    2017-01-01

    The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers to 40 unusual questions, remember the answers and recall them in the scanner. Un-learned questions were randomly presented at the recalling stage in order to elicited search impulse. Comparing to the pre-test, subjects in the post-test reported higher impulse to use search engines to answer un-learned questions. Consistently, subjects showed higher brain activations in dorsolateral prefrontal cortex and anterior cingulate cortex in the post-test than in the pre-test. In addition, there were significant positive correlations self-reported search impulse and brain responses in the frontal areas. The results suggest that a simple six-day's Internet search training can make people dependent on the search tools when facing unknown issues. People are easily dependent on the Internet search engines.

  17. Short-term Internet search using makes people rely on search engines when facing unknown issues.

    Directory of Open Access Journals (Sweden)

    Yifan Wang

    Full Text Available The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers to 40 unusual questions, remember the answers and recall them in the scanner. Un-learned questions were randomly presented at the recalling stage in order to elicited search impulse. Comparing to the pre-test, subjects in the post-test reported higher impulse to use search engines to answer un-learned questions. Consistently, subjects showed higher brain activations in dorsolateral prefrontal cortex and anterior cingulate cortex in the post-test than in the pre-test. In addition, there were significant positive correlations self-reported search impulse and brain responses in the frontal areas. The results suggest that a simple six-day's Internet search training can make people dependent on the search tools when facing unknown issues. People are easily dependent on the Internet search engines.

  18. Genetics Home Reference: X-linked spondyloepiphyseal dysplasia tarda

    Science.gov (United States)

    ... Educational Resources (6 links) Cincinnati Children's Hospital: Coxa Vera Disease InfoSearch: Spondyloepiphyseal dysplasia tarda X-linked Johns ... Free article on PubMed Central Savarirayan R, Thompson E, Gécz J. Spondyloepiphyseal dysplasia tarda (SEDL, MIM #313400). ...

  19. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse Commonly Abused Drugs Charts Emerging Trends and Alerts ...

  20. A Taxonomic Search Engine: Federating taxonomic databases using web services

    Directory of Open Access Journals (Sweden)

    Page Roderic DM

    2005-03-01

    Full Text Available Abstract Background The taxonomic name of an organism is a key link between different databases that store information on that organism. However, in the absence of a single, comprehensive database of organism names, individual databases lack an easy means of checking the correctness of a name. Furthermore, the same organism may have more than one name, and the same name may apply to more than one organism. Results The Taxonomic Search Engine (TSE is a web application written in PHP that queries multiple taxonomic databases (ITIS, Index Fungorum, IPNI, NCBI, and uBIO and summarises the results in a consistent format. It supports "drill-down" queries to retrieve a specific record. The TSE can optionally suggest alternative spellings the user can try. It also acts as a Life Science Identifier (LSID authority for the source taxonomic databases, providing globally unique identifiers (and associated metadata for each name. Conclusion The Taxonomic Search Engine is available at http://darwin.zoology.gla.ac.uk/~rpage/portal/ and provides a simple demonstration of the potential of the federated approach to providing access to taxonomic names.

  1. Testing search strategies for systematic reviews in the Medline literature database through PubMed.

    Science.gov (United States)

    Volpato, Enilze S N; Betini, Marluci; El Dib, Regina

    2014-04-01

    A high-quality electronic search is essential in ensuring accuracy and completeness in retrieved records for the conducting of a systematic review. We analysed the available sample of search strategies to identify the best method for searching in Medline through PubMed, considering the use or not of parenthesis, double quotation marks, truncation and use of a simple search or search history. In our cross-sectional study of search strategies, we selected and analysed the available searches performed during evidence-based medicine classes and in systematic reviews conducted in the Botucatu Medical School, UNESP, Brazil. We analysed 120 search strategies. With regard to the use of phrase searches with parenthesis, there was no difference between the results with and without parenthesis and simple searches or search history tools in 100% of the sample analysed (P = 1.0). The number of results retrieved by the searches analysed was smaller using double quotations marks and using truncation compared with the standard strategy (P = 0.04 and P = 0.08, respectively). There is no need to use phrase-searching parenthesis to retrieve studies; however, we recommend the use of double quotation marks when an investigator attempts to retrieve articles in which a term appears to be exactly the same as what was proposed in the search form. Furthermore, we do not recommend the use of truncation in search strategies in the Medline via PubMed. Although the results of simple searches or search history tools were the same, we recommend using the latter.

  2. Missing Links in Middle School: Developing Use of Disciplinary Relatedness in Evaluating Internet Search Results.

    Directory of Open Access Journals (Sweden)

    Frank C Keil

    Full Text Available In the "digital native" generation, internet search engines are a commonly used source of information. However, adolescents may fail to recognize relevant search results when they are related in discipline to the search topic but lack other cues. Middle school students, high school students, and adults rated simulated search results for relevance to the search topic. The search results were designed to contrast deep discipline-based relationships with lexical similarity to the search topic. Results suggest that the ability to recognize disciplinary relatedness without supporting cues may continue to develop into high school. Despite frequent search engine usage, younger adolescents may require additional support to make the most of the information available to them.

  3. Pythagoras' celestial spheres in the context of a simple model for quantization of planetary orbits

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira Neto, Marcal de [Instituto de Quimica, Universidade de Brasilia, Campus Universitario, Asa Norte, 70904-970 Brasilia, DF (Brazil)]. E-mail: marcal@unb.br

    2006-10-15

    In the present article we attempt to search for a correlation between Pythagoras and Kepler's ideas on harmony of the celestial spheres through simple quantization procedure to describe planetary orbits in our solar system. It is reasoned that starting from a Bohr-like atomic model, planetary mean radii and periods of revolution can be obtained from a set of small integers and just one input parameter given by the mean planetary radius of Mercury. It is also shown that the mean planetary distances can be calculated with the help of a Schroedinger-type equation considering the flatness of the solar system. An attempt to obtain planetary radii using both gravitational and electrostatic approaches linked by Newton's dimensionless constant of gravity is presented.

  4. Using Critical Thinking To Conduct Effective Searches of Online Resources.

    Science.gov (United States)

    Brem, Sarah K.; Boyes, Andrea J.

    2000-01-01

    Complements guidelines addressing the mechanics of online searching by considering how treating searching as exercises in critical thinking can improve the use of online resources. Discusses metacognition, hypothesis testing, and argumentation, with illustrative examples and links to tools that facilitate the searching process. (SLD)

  5. Question Answering for Dutch : Simple does it

    NARCIS (Netherlands)

    Hoekstra, A.H.; Hiemstra, Djoerd; van der Vet, P.E.; Huibers, Theo W.C.; Schobbens, Pierre-Yves; Vanhoof, Wim; Schwanen, Gabriel

    2006-01-01

    When people pose questions in natural language to search for information on the web, the role of question answering (QA) systems becomes important. In this paper the QAsystem simpleQA, capable of answering Dutch questions on which the answer is a person or a location, is described. The system's

  6. Drugs + HIV, Learn the Link

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    Full Text Available Skip to main content En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu ...

  7. Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking

    OpenAIRE

    Lee, Samuel M.; Chin, Lih-Shen; Li, Lian

    2012-01-01

    Mutations in small integral membrane protein of lysosome/late endosome (SIMPLE) cause autosomal dominant, Charcot-Marie-Tooth disease (CMT) type 1C. The cellular function of SIMPLE is unknown and the pathogenic mechanism of SIMPLE mutations remains elusive. Here, we report that SIMPLE interacted and colocalized with endosomal sorting complex required for transport (ESCRT) components STAM1, Hrs, and TSG101 on early endosomes and functioned with the ESCRT machinery in the control of endosome-to...

  8. A Statistical Ontology-Based Approach to Ranking for Multiword Search

    Science.gov (United States)

    Kim, Jinwoo

    2013-01-01

    Keyword search is a prominent data retrieval method for the Web, largely because the simple and efficient nature of keyword processing allows a large amount of information to be searched with fast response. However, keyword search approaches do not formally capture the clear meaning of a keyword query and fail to address the semantic relationships…

  9. Search for non-Gaussian events in the data of the VIRGO E4 engineering run

    International Nuclear Information System (INIS)

    Collaboration, The VIRGO; Verkindt, Didier

    2003-01-01

    This work is a first attempt to search for glitch events in the data of the VIRGO Central Interferometer (CITF). In the first step, using simple algorithms, we searched for strong glitches in the interferometer's output photodiodes signals over the three days of data of the last engineering run. In the second step, we focused on 10 hours of data taken when the interferometer was locked and stable. The events found in the dark-fringe signal during this period are all within 3 rms of the mean output value of each algorithm and are, in some cases, linked to a beat between the powerline 50 Hz contamination and a 43.7 Hz line that comes from injection-system components. The main conclusions are that, at this level of analysis, the algorithms used have found no strong glitch-like events in the dark-fringe signal of VIRGO and that removing spectral lines like the 50 Hz is essential to further investigation

  10. A Webometric Analysis of ISI Medical Journals Using Yahoo, AltaVista, and All the Web Search Engines

    Directory of Open Access Journals (Sweden)

    Zohreh Zahedi

    2010-12-01

    Full Text Available The World Wide Web is an important information source for scholarly communications. Examining the inlinks via webometrics studies has attracted particular interests among information researchers. In this study, the number of inlinks to 69 ISI medical journals retrieved by Yahoo, AltaVista, and All The web Search Engines were examined via a comparative and Webometrics study. For data analysis, SPSS software was employed. Findings revealed that British Medical Journal website attracted the most links of all in the three search engines. There is a significant correlation between the number of External links and the ISI impact factor. The most significant correlation in the three search engines exists between external links of Yahoo and AltaVista (100% and the least correlation is found between external links of All The web & the number of pages of AltaVista (0.51. There is no significant difference between the internal links & the number of pages found by the three search engines. But in case of impact factors, significant differences are found between these three search engines. So, the study shows that journals with higher impact factor attract more links to their websites. It also indicates that the three search engines are significantly different in terms of total links, outlinks and web impact factors

  11. The Cost of Cache-Oblivious Searching

    DEFF Research Database (Denmark)

    Bender, Michael A.; Brodal, Gert Stølting; Fagerberg, Rolf

    2003-01-01

    , multilevel memory hierarchies can be modelled. It is shown that as k grows, the search costs of the optimal k-level DAM search structure and of the optimal cache-oblivious search structure rapidly converge. This demonstrates that for a multilevel memory hierarchy, a simple cache-oblivious structure almost......Tight bounds on the cost of cache-oblivious searching are proved. It is shown that no cache-oblivious search structure can guarantee that a search performs fewer than lg e log B N block transfers between any two levels of the memory hierarchy. This lower bound holds even if all of the block sizes...... the random placement of the rst element of the structure in memory. As searching in the Disk Access Model (DAM) can be performed in log B N + 1 block transfers, this result shows a separation between the 2-level DAM and cacheoblivious memory-hierarchy models. By extending the DAM model to k levels...

  12. GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.

    Science.gov (United States)

    Naito, Yuki; Bono, Hidemasa

    2012-07-01

    GGRNA (http://GGRNA.dbcls.jp/) is a Google-like, ultrafast search engine for genes and transcripts. The web server accepts arbitrary words and phrases, such as gene names, IDs, gene descriptions, annotations of gene and even nucleotide/amino acid sequences through one simple search box, and quickly returns relevant RefSeq transcripts. A typical search takes just a few seconds, which dramatically enhances the usability of routine searching. In particular, GGRNA can search sequences as short as 10 nt or 4 amino acids, which cannot be handled easily by popular sequence analysis tools. Nucleotide sequences can be searched allowing up to three mismatches, or the query sequences may contain degenerate nucleotide codes (e.g. N, R, Y, S). Furthermore, Gene Ontology annotations, Enzyme Commission numbers and probe sequences of catalog microarrays are also incorporated into GGRNA, which may help users to conduct searches by various types of keywords. GGRNA web server will provide a simple and powerful interface for finding genes and transcripts for a wide range of users. All services at GGRNA are provided free of charge to all users.

  13. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Prevention Recovery Substance Use and SUDs in LGBT Populations Treatment Trends & Statistics Women and Drugs Publications Search ... the link between drug misuse and HIV/AIDS, populations most at risk, trends in HIV/AIDS, and ...

  14. Modeling reproductive decisions with simple heuristics

    Directory of Open Access Journals (Sweden)

    Peter Todd

    2013-10-01

    Full Text Available BACKGROUND Many of the reproductive decisions that humans make happen without much planning or forethought, arising instead through the use of simple choice rules or heuristics that involve relatively little information and processing. Nonetheless, these heuristic-guided decisions are typically beneficial, owing to humans' ecological rationality - the evolved fit between our constrained decision mechanisms and the adaptive problems we face. OBJECTIVE This paper reviews research on the ecological rationality of human decision making in the domain of reproduction, showing how fertility-related decisions are commonly made using various simple heuristics matched to the structure of the environment in which they are applied, rather than being made with information-hungry mechanisms based on optimization or rational economic choice. METHODS First, heuristics for sequential mate search are covered; these heuristics determine when to stop the process of mate search by deciding that a good-enough mate who is also mutually interested has been found, using a process of aspiration-level setting and assessing. These models are tested via computer simulation and comparison to demographic age-at-first-marriage data. Next, a heuristic process of feature-based mate comparison and choice is discussed, in which mate choices are determined by a simple process of feature-matching with relaxing standards over time. Parental investment heuristics used to divide resources among offspring are summarized. Finally, methods for testing the use of such mate choice heuristics in a specific population over time are then described.

  15. Drugs + HIV, Learn the Link

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    Full Text Available Skip to main content En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse ...

  16. Drugs + HIV, Learn the Link

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    Full Text Available ... Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter ... Network TV Organizations: AIDS.gov AIDS Alliance for Children, Youth and Families The American Academy of Child & ...

  17. Drugs + HIV, Learn the Link

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    Full Text Available ... and Drugs Publications Search Publications Orderable DrugFacts Research Reports Mind Over Matter Science of Addiction Funding Funding ... transmitting HIV/AIDS or other infectious diseases. Research Reports: HIV/AIDS : Explores the link between drug misuse ...

  18. Clinical and linkage study of a large family with simple ectopia lentis linked to FBN1

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, M.J.; Roberts, J.; Partington, M.W. [Newcastle and Northern New South Wales Genetics Service (Australia); Colley, P.W. [John Hunter Hospital, Newcastle (Australia); Hollway, G.E.; Kozman, H.M.; Mulley, J.C. [Adelaide Children`s Hospital, North Adelaide (Australia)

    1994-10-15

    Simple ectopia lentis (EL) was studied in a large family, by clinical examination and analysis of linkage to markers in the region of FBN1, the gene for fibrillin which causes Marfan syndrome on chromosome 15. No patient had clinical or echocardiographic evidence of Marfan syndrome, although there was a trend towards relatively longer measurements of height; lower segment; arm span; middle finger, hand, and foot length in the affected members of the family, compared with unaffected sibs of the same sex. Analysis of linkage to intragenic FBN1 markers was inconclusive because they were relatively uninformative. Construction of a multipoint background map from the CEPH reference families identified microsatellite markers linked closely to FBN1 which could demonstrate linkage of EL in this family to the FBN1 region. LINKMAP analysis detected a multipoint lod score of 5.68 at D15S119, a marker approximately 6 cM distal to FBN1, and a multipoint lod score of 5.04 at FBN1. The EL gene in this family is likely to be allelic to Marfan syndrome, and molecular characterization of the FBN1 mutation should now be possible. 25 refs., 6 figs., 2 tabs.

  19. Best, Useful and Objective Precisions for Information Retrieval of Three Search Methods in PubMed and iPubMed

    Directory of Open Access Journals (Sweden)

    Somayyeh Nadi Ravandi

    2016-10-01

    Full Text Available MEDLINE is one of the valuable sources of medical information on the Internet. Among the different open access sites of MEDLINE, PubMed is the best-known site. In 2010, iPubMed was established with an interaction-fuzzy search method for MEDLINE access. In the present work, we aimed to compare the precision of the retrieved sources (Best, Useful and Objective precision in the PubMed and iPubMed using two search methods (simple and MeSH search in PubMed and interaction-fuzzy method in iPubmed. During our semi-empirical study period, we held training workshops for 61 students of higher education to teach them Simple Search, MeSH Search, and Fuzzy-Interaction Search methods. Then, the precision of 305 searches for each method prepared by the students was calculated on the basis of Best precision, Useful precision, and Objective precision formulas. Analyses were done in SPSS version 11.5 using the Friedman and Wilcoxon Test, and three precisions obtained with the three precision formulas were studied for the three search methods. The mean precision of the interaction-fuzzy Search method was higher than that of the simple search and MeSH search for all three types of precision, i.e., Best precision, Useful precision, and Objective precision, and the Simple search method was in the next rank, and their mean precisions were significantly different (P < 0.001. The precision of the interaction-fuzzy search method in iPubmed was investigated for the first time. Also for the first time, three types of precision were evaluated in PubMed and iPubmed. The results showed that the Interaction-Fuzzy search method is more precise than using the natural language search (simple search and MeSH search, and users of this method found papers that were more related to their queries; even though search in Pubmed is useful, it is important that users apply new search methods to obtain the best results.

  20. CBP Customs Rulings Online Search System (CROSS)

    Data.gov (United States)

    Department of Homeland Security — CROSS is a searchable database of CBP rulings that can be retrieved based on simple or complex search characteristics using keywords and Boolean operators. CROSS has...

  1. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of ... Director of the National Institute on Drug Abuse, Dr. Nora D. Volkow. Message from the Director The ...

  2. Drugs + HIV, Learn the Link

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    Full Text Available ... En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook ... HIV infection. It contains information for young people, parents and teachers, and the media with links to ...

  3. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of ... In animal studies, methamphetamine has been shown to increase the amount of HIV in brain cells 1 . ...

  4. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... NIDA Donating to NIDA Frequently Asked Questions Contact Us Sharing Tools and Badges Other Resources Strategic Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ...

  5. Personality moderates the links of social identity with work motivation and job searching.

    Science.gov (United States)

    Baay, Pieter E; van Aken, Marcel A G; van der Lippe, Tanja; de Ridder, Denise T D

    2014-01-01

    Work motivation is critical for successful school-to-work transitions, but little is known about its determinants among labor market entrants. Applying a social identity framework, we examined whether work motivation and job searching are social-contextually determined. We expected that some job seekers are more sensitive to contextual influence, depending on their personality. Mediation analyses on 591 Dutch vocational training students indicate that the perception of more positive work norms in someone's social context was related to higher levels of intrinsic motivation, which in turn predicted higher preparatory job search behavior and job search intentions. Multi-group analysis shows that perceived work norms more strongly predict work motivation among overcontrollers compared to resilients and undercontrollers. In conclusion, work motivation and job searching appear contextually determined: especially among those sensitive to contextual influence, people seem to work when they believe that is what people like them do.

  6. Ontology-Based Querying with Bio2RDF's Linked Open Data.

    Science.gov (United States)

    Callahan, Alison; Cruz-Toledo, José; Dumontier, Michel

    2013-04-15

    A key activity for life scientists in this post "-omics" age involves searching for and integrating biological data from a multitude of independent databases. However, our ability to find relevant data is hampered by non-standard web and database interfaces backed by an enormous variety of data formats. This heterogeneity presents an overwhelming barrier to the discovery and reuse of resources which have been developed at great public expense.To address this issue, the open-source Bio2RDF project promotes a simple convention to integrate diverse biological data using Semantic Web technologies. However, querying Bio2RDF remains difficult due to the lack of uniformity in the representation of Bio2RDF datasets. We describe an update to Bio2RDF that includes tighter integration across 19 new and updated RDF datasets. All available open-source scripts were first consolidated to a single GitHub repository and then redeveloped using a common API that generates normalized IRIs using a centralized dataset registry. We then mapped dataset specific types and relations to the Semanticscience Integrated Ontology (SIO) and demonstrate simplified federated queries across multiple Bio2RDF endpoints. This coordinated release marks an important milestone for the Bio2RDF open source linked data framework. Principally, it improves the quality of linked data in the Bio2RDF network and makes it easier to access or recreate the linked data locally. We hope to continue improving the Bio2RDF network of linked data by identifying priority databases and increasing the vocabulary coverage to additional dataset vocabularies beyond SIO.

  7. Drugs + HIV, Learn the Link

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    Full Text Available ... the News NIDA Notes Podcasts E-Newsletters Public Education Projects Contact the Press Office Meetings & Events Media ... Plan Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn ...

  8. Drugs + HIV, Learn the Link

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    Full Text Available ... News NIDA Notes Podcasts E-Newsletters Public Education Projects Contact the Press Office Meetings & Events Media Guide ... Search Share Print Home » News & Events » Public Education Projects » Learn the Link - Drugs and HIV Learn the ...

  9. `Googling' Terrorists: Are Northern Irish Terrorists Visible on Internet Search Engines?

    Science.gov (United States)

    Reilly, P.

    In this chapter, the analysis suggests that Northern Irish terrorists are not visible on Web search engines when net users employ conventional Internet search techniques. Editors of mass media organisations traditionally have had the ability to decide whether a terrorist atrocity is `newsworthy,' controlling the `oxygen' supply that sustains all forms of terrorism. This process, also known as `gatekeeping,' is often influenced by the norms of social responsibility, or alternatively, with regard to the interests of the advertisers and corporate sponsors that sustain mass media organisations. The analysis presented in this chapter suggests that Internet search engines can also be characterised as `gatekeepers,' albeit without the ability to shape the content of Websites before it reaches net users. Instead, Internet search engines give priority retrieval to certain Websites within their directory, pointing net users towards these Websites rather than others on the Internet. Net users are more likely to click on links to the more `visible' Websites on Internet search engine directories, these sites invariably being the highest `ranked' in response to a particular search query. A number of factors including the design of the Website and the number of links to external sites determine the `visibility' of a Website on Internet search engines. The study suggests that Northern Irish terrorists and their sympathisers are unlikely to achieve a greater degree of `visibility' online than they enjoy in the conventional mass media through the perpetration of atrocities. Although these groups may have a greater degree of freedom on the Internet to publicise their ideologies, they are still likely to be speaking to the converted or members of the press. Although it is easier to locate Northern Irish terrorist organisations on Internet search engines by linking in via ideology, ideological description searches, such as `Irish Republican' and `Ulster Loyalist,' are more likely to

  10. Keep It Simple: A Lesson in Linking Teens to Health Care

    Science.gov (United States)

    Eisler, Alexandra; Avellino, Lia; Chilcoat, Deborah; Schlanger, Karen

    2016-01-01

    The "Keep It Simple" package, which includes a short animated film (available online for streaming or download), a lesson plan, and supporting materials, was designed to be used with adolescents ages 15-19 to empower them to seek sexual and reproductive health care, and emphasize the availability of long-acting reversible contraception…

  11. Bad news: The influence of news coverage and Google searches on Gardasil adverse event reporting.

    Science.gov (United States)

    Faasse, Kate; Porsius, Jarry T; Faasse, Jonathan; Martin, Leslie R

    2017-12-14

    Human papilloma virus vaccines are a safe and effective tool for reducing HPV infections that can cause cervical cancer. However, uptake of these vaccines has been suboptimal, with many people holding negative beliefs and misconceptions. Such beliefs have been linked with the experience of unpleasant side effects following medical treatment, and media coverage may heighten such concerns. The present study sought to assess the influence of news coverage (number of news articles per month) on adverse event reporting in response to Gardasil vaccination in New Zealand over a 7.5-year period, and whether the influence of news coverage was mediated by internet search activity (Google search volumes). Multiple linear regression analyses and simple mediation analyses were used, controlling for year and number of vaccinations delivered. News coverage in the previous month, and Google search volumes in the same month, were significant predictors of adverse event reporting, after accounting for vaccination rates and year. Concurrent Google search volumes partially mediated the effect of prior news coverage. The results suggest that some of the adverse events reported were not related to the vaccination itself, but to news coverage and internet search volumes, which may have contributed to public concerns about potentially unpleasant or harmful outcomes. These findings have implications for the importance of psychological and social factors in adverse event reporting, and the role of the news media in disseminating health information. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. 28 CFR 541.48 - Search of control unit inmates.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Search of control unit inmates. 541.48... INMATE DISCIPLINE AND SPECIAL HOUSING UNITS Control Unit Programs § 541.48 Search of control unit inmates. (a) The Warden at an institution housing a control unit may order a digital or simple instrument...

  13. Quantum search of a real unstructured database

    Science.gov (United States)

    Broda, Bogusław

    2016-02-01

    A simple circuit implementation of the oracle for Grover's quantum search of a real unstructured classical database is proposed. The oracle contains a kind of quantumly accessible classical memory, which stores the database.

  14. Influence of social presence on eye movements in visual search tasks.

    Science.gov (United States)

    Liu, Na; Yu, Ruifeng

    2017-12-01

    This study employed an eye-tracking technique to investigate the influence of social presence on eye movements in visual search tasks. A total of 20 male subjects performed visual search tasks in a 2 (target presence: present vs. absent) × 2 (task complexity: complex vs. simple) × 2 (social presence: alone vs. a human audience) within-subject experiment. Results indicated that the presence of an audience could evoke a social facilitation effect on response time in visual search tasks. Compared with working alone, the participants made fewer and shorter fixations, larger saccades and shorter scan path in simple search tasks and more and longer fixations, smaller saccades and longer scan path in complex search tasks when working with an audience. The saccade velocity and pupil diameter in the audience-present condition were larger than those in the working-alone condition. No significant change in target fixation number was observed between two social presence conditions. Practitioner Summary: This study employed an eye-tracking technique to examine the influence of social presence on eye movements in visual search tasks. Results clarified the variation mechanism and characteristics of oculomotor scanning induced by social presence in visual search.

  15. Competing intelligent search agents in global optimization

    Energy Technology Data Exchange (ETDEWEB)

    Streltsov, S.; Vakili, P. [Boston Univ., MA (United States); Muchnik, I. [Rutgers Univ., Piscataway, NJ (United States)

    1996-12-31

    In this paper we present a new search methodology that we view as a development of intelligent agent approach to the analysis of complex system. The main idea is to consider search process as a competition mechanism between concurrent adaptive intelligent agents. Agents cooperate in achieving a common search goal and at the same time compete with each other for computational resources. We propose a statistical selection approach to resource allocation between agents that leads to simple and efficient on average index allocation policies. We use global optimization as the most general setting that encompasses many types of search problems, and show how proposed selection policies can be used to improve and combine various global optimization methods.

  16. Search and Hyperlinking Task at MediaEval 2012

    NARCIS (Netherlands)

    Eskevich, Maria; Jones, Gareth J.F.; Chen, Shu; Aly, Robin; Ordelman, Roeland J.F.; Larson, Martha

    2012-01-01

    The Search and Hyperlinking Task was one of the Brave New Tasks at MediaEval 2012. The Task consisted of two sub- tasks which focused on search and linking in retrieval from a collection of semi-professional video content. These tasks followed up on research carried out within the MediaEval 2011

  17. Materializing the web of linked data

    CERN Document Server

    Konstantinou, Nikolaos

    2015-01-01

    This book explains the Linked Data domain by adopting a bottom-up approach: it introduces the fundamental Semantic Web technologies and building blocks, which are then combined into methodologies and end-to-end examples for publishing datasets as Linked Data, and use cases that harness scholarly information and sensor data. It presents how Linked Data is used for web-scale data integration, information management and search. Special emphasis is given to the publication of Linked Data from relational databases as well as from real-time sensor data streams. The authors also trace the transformation from the document-based World Wide Web into a Web of Data. Materializing the Web of Linked Data is addressed to researchers and professionals studying software technologies, tools and approaches that drive the Linked Data ecosystem, and the Web in general.

  18. Drugs + HIV, Learn the Link

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    Full Text Available Skip to main content En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook LinkedIn Twitter YouTube Flickr RSS Menu Home Drugs of Abuse Commonly Abused Drugs Charts ...

  19. Use of search engine optimization factors for Google page rank prediction

    OpenAIRE

    Tvrdi, Barbara

    2012-01-01

    Over the years, search engines have become an important tool for finding information. It is known that users select the link on the first page of search results in 62% of the cases. Search engine optimization techniques enable website improvement and therefore a better ranking in search engines. The exact specification of the factors that affect website ranking is not disclosed by search engine owners. In this thesis we tried to choose some most frequently mentioned search engine optimizatio...

  20. Analysis of Search Engines and Meta Search Engines\\\\\\' Position by University of Isfahan Users Based on Rogers\\\\\\' Diffusion of Innovation Theory

    Directory of Open Access Journals (Sweden)

    Maryam Akbari

    2012-10-01

    , among simple and advanced pages of Google, a specific bias toward simple search pages could be seen in users. This part of the study confirmed Rogers’ theory. Other results of the study indicated that renouncement of innovation was not only in decision phase. This part of the investigation was in conflict with Rogers’ theory.

  1. The HMMER Web Server for Protein Sequence Similarity Search.

    Science.gov (United States)

    Prakash, Ananth; Jeffryes, Matt; Bateman, Alex; Finn, Robert D

    2017-12-08

    Protein sequence similarity search is one of the most commonly used bioinformatics methods for identifying evolutionarily related proteins. In general, sequences that are evolutionarily related share some degree of similarity, and sequence-search algorithms use this principle to identify homologs. The requirement for a fast and sensitive sequence search method led to the development of the HMMER software, which in the latest version (v3.1) uses a combination of sophisticated acceleration heuristics and mathematical and computational optimizations to enable the use of profile hidden Markov models (HMMs) for sequence analysis. The HMMER Web server provides a common platform by linking the HMMER algorithms to databases, thereby enabling the search for homologs, as well as providing sequence and functional annotation by linking external databases. This unit describes three basic protocols and two alternate protocols that explain how to use the HMMER Web server using various input formats and user defined parameters. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  2. Adaptation and search: from Dexter and AHAM to GAF

    NARCIS (Netherlands)

    Knutov, E.; De Bra, P.M.E.; Pechenizkiy, M.; Chignell, M.H.; Toms, E.

    2010-01-01

    Adaptive Hypermedia Systems (AHS) have long been concentrating on adaptive guidance of links between domain concepts. Here we show parallels between navigation and linking in adaptive hypermedia on the one hand and information searching or querying on the other hand. We present a transition towards

  3. Application of a fast sorting algorithm to the assignment of mass spectrometric cross-linking data.

    Science.gov (United States)

    Petrotchenko, Evgeniy V; Borchers, Christoph H

    2014-09-01

    Cross-linking combined with MS involves enzymatic digestion of cross-linked proteins and identifying cross-linked peptides. Assignment of cross-linked peptide masses requires a search of all possible binary combinations of peptides from the cross-linked proteins' sequences, which becomes impractical with increasing complexity of the protein system and/or if digestion enzyme specificity is relaxed. Here, we describe the application of a fast sorting algorithm to search large sequence databases for cross-linked peptide assignments based on mass. This same algorithm has been used previously for assigning disulfide-bridged peptides (Choi et al., ), but has not previously been applied to cross-linking studies. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Introduction to Search with Sphinx From installation to relevance tuning

    CERN Document Server

    Aksyonoff, Andrew

    2011-01-01

    This concise introduction to Sphinx shows you how to use this free software to index an enormous number of documents and provide fast results to both simple and complex searches. Written by the creator of Sphinx, this authoritative book is short and to the point. Understand the particular way Sphinx conducts searchesInstall and configure Sphinx, and run a few basic testsIssue basic queries to Sphinx at the application levelLearn the syntax of search text and the effects of various search optionsGet strategies for dealing with large data sets, such as multi-index searchingApply relevance and r

  5. Searching for light dark matter with the SLAC millicharge experiment.

    Science.gov (United States)

    Diamond, M; Schuster, P

    2013-11-27

    New sub-GeV gauge forces ("dark photons") that kinetically mix with the photon provide a promising scenario for MeV-GeV dark matter and are the subject of a program of searches at fixed-target and collider facilities around the world. In such models, dark photons produced in collisions may decay invisibly into dark-matter states, thereby evading current searches. We reexamine results of the SLAC mQ electron beam dump experiment designed to search for millicharged particles and find that it was strongly sensitive to any secondary beam of dark matter produced by electron-nucleus collisions in the target. The constraints are competitive for dark photon masses in the ~1-30 MeV range, covering part of the parameter space that can reconcile the apparent (g-2)(μ) anomaly. Simple adjustments to the original SLAC search for millicharges may extend sensitivity to cover a sizable portion of the remaining (g-2)(μ) anomaly-motivated region. The mQ sensitivity is therefore complementary to ongoing searches for visible decays of dark photons. Compared to existing direct-detection searches, mQ sensitivity to electron-dark-matter scattering cross sections is more than an order of magnitude better for a significant range of masses and couplings in simple models.

  6. Nephrology and astrology--is there a link?

    Science.gov (United States)

    Hughes, S

    1990-07-01

    Astrologers presume a link between the susceptibility of particular organs to disease and signs of the Zodiac. A simple test of the positive connection between renal disease and the sign of Libra was undertaken by studying the birth dates of consecutive nephrology in-patient admissions. No significant link was found on analysis, thus disproving the traditional astrologers' claims.

  7. A Simple ELISA Exercise for Undergraduate Biology.

    Science.gov (United States)

    Baker, William P.; Moore, Cathy R.

    Understanding of immunological techniques such as the Enzyme Linked Immuno Sorbent Assay (ELISA) is an important part of instructional units in human health, developmental biology, microbiology, and biotechnology. This paper describes a simple ELISA exercise for undergraduate biology that effectively simulates the technique using a paper model.…

  8. Predicting consumer behavior with Web search.

    Science.gov (United States)

    Goel, Sharad; Hofman, Jake M; Lahaie, Sébastien; Pennock, David M; Watts, Duncan J

    2010-10-12

    Recent work has demonstrated that Web search volume can "predict the present," meaning that it can be used to accurately track outcomes such as unemployment levels, auto and home sales, and disease prevalence in near real time. Here we show that what consumers are searching for online can also predict their collective future behavior days or even weeks in advance. Specifically we use search query volume to forecast the opening weekend box-office revenue for feature films, first-month sales of video games, and the rank of songs on the Billboard Hot 100 chart, finding in all cases that search counts are highly predictive of future outcomes. We also find that search counts generally boost the performance of baseline models fit on other publicly available data, where the boost varies from modest to dramatic, depending on the application in question. Finally, we reexamine previous work on tracking flu trends and show that, perhaps surprisingly, the utility of search data relative to a simple autoregressive model is modest. We conclude that in the absence of other data sources, or where small improvements in predictive performance are material, search queries provide a useful guide to the near future.

  9. An algorithm for link restoration of wavelength routing optical networks

    DEFF Research Database (Denmark)

    Limal, Emmanuel; Stubkjær, Kristian

    1999-01-01

    We present an algorithm for restoration of single link failure in wavelength routing multihop optical networks. The algorithm is based on an innovative study of networks using graph theory. It has the following original features: it (i) assigns working and spare channels simultaneously, (ii......) prevents the search for unacceptable routing paths by pointing out channels required for restoration, (iii) offers a high utilization of the capacity resources and (iv) allows a trivial search for the restoration paths. The algorithm is for link restoration of networks without wavelength translation. Its...

  10. Report on the Second Workshop on Supporting Complex Search Tasks

    DEFF Research Database (Denmark)

    Koolen, Marijn; Kamps, Jaap; Bogers, Toine

    2017-01-01

    There is broad consensus in the field of IR that search is complex in many use cases and applications, both on the Web and in domain-specific collections, and both in our professional and in our daily life. Yet our understanding of complex search tasks, in comparison to simple look up tasks...

  11. Quad-Polarization Transmission for High-Capacity IM/DD Links

    DEFF Research Database (Denmark)

    Estaran Tolosa, Jose Manuel; Castaneda, Mario A. Usuga; Porto da Silva, Edson

    2014-01-01

    We report the first experimental demonstration of IM/DD links usi ng four states of polarization. Fiber - Induced polarization rotation is compensated with a simple tracking algorithm operating on the Stokes space. The principle is prove n at 128 Gb/s over 2 - km SSMF......We report the first experimental demonstration of IM/DD links usi ng four states of polarization. Fiber - Induced polarization rotation is compensated with a simple tracking algorithm operating on the Stokes space. The principle is prove n at 128 Gb/s over 2 - km SSMF...

  12. Pip and pop : Non-spatial auditory signals improve spatial visual search

    NARCIS (Netherlands)

    Burg, E. van der; Olivers, C.N.L.; Bronkhorst, A.W.; Theeuwes, J.

    2008-01-01

    Searching for an object within a cluttered, continuously changing environment can be a very time-consuming process. The authors show that a simple auditory pip drastically decreases search times for a synchronized visual object that is normally very difficult to find. This effect occurs even though

  13. The CTBTO Link to the database of the International Seismological Centre (ISC)

    Science.gov (United States)

    Bondar, I.; Storchak, D. A.; Dando, B.; Harris, J.; Di Giacomo, D.

    2011-12-01

    The CTBTO Link to the database of the International Seismological Centre (ISC) is a project to provide access to seismological data sets maintained by the ISC using specially designed interactive tools. The Link is open to National Data Centres and to the CTBTO. By means of graphical interfaces and database queries tailored to the needs of the monitoring community, the users are given access to a multitude of products. These include the ISC and ISS bulletins, covering the seismicity of the Earth since 1904; nuclear and chemical explosions; the EHB bulletin; the IASPEI Reference Event list (ground truth database); and the IDC Reviewed Event Bulletin. The searches are divided into three main categories: The Area Based Search (a spatio-temporal search based on the ISC Bulletin), the REB search (a spatio-temporal search based on specific events in the REB) and the IMS Station Based Search (a search for historical patterns in the reports of seismic stations close to a particular IMS seismic station). The outputs are HTML based web-pages with a simplified version of the ISC Bulletin showing the most relevant parameters with access to ISC, GT, EHB and REB Bulletins in IMS1.0 format for single or multiple events. The CTBTO Link offers a tool to view REB events in context within the historical seismicity, look at observations reported by non-IMS networks, and investigate station histories and residual patterns for stations registered in the International Seismographic Station Registry.

  14. A Harmony Search Algorithm approach for optimizing traffic signal timings

    Directory of Open Access Journals (Sweden)

    Mauro Dell'Orco

    2013-07-01

    Full Text Available In this study, a bi-level formulation is presented for solving the Equilibrium Network Design Problem (ENDP. The optimisation of the signal timing has been carried out at the upper-level using the Harmony Search Algorithm (HSA, whilst the traffic assignment has been carried out through the Path Flow Estimator (PFE at the lower level. The results of HSA have been first compared with those obtained using the Genetic Algorithm, and the Hill Climbing on a two-junction network for a fixed set of link flows. Secondly, the HSA with PFE has been applied to the medium-sized network to show the applicability of the proposed algorithm in solving the ENDP. Additionally, in order to test the sensitivity of perceived travel time error, we have used the HSA with PFE with various level of perceived travel time. The results showed that the proposed method is quite simple and efficient in solving the ENDP.

  15. A Simple Forecasting Model Linking Macroeconomic Policy to Industrial Employment Demand.

    Science.gov (United States)

    Malley, James R.; Hady, Thomas F.

    A study detailed further a model linking monetary and fiscal policy to industrial employment in metropolitan and nonmetropolitan areas of four United States regions. The model was used to simulate the impacts on area and regional employment of three events in the economy: changing real gross national product (GNP) via monetary policy, holding the…

  16. Quantum-circuit model of Hamiltonian search algorithms

    International Nuclear Information System (INIS)

    Roland, Jeremie; Cerf, Nicolas J.

    2003-01-01

    We analyze three different quantum search algorithms, namely, the traditional circuit-based Grover's algorithm, its continuous-time analog by Hamiltonian evolution, and the quantum search by local adiabatic evolution. We show that these algorithms are closely related in the sense that they all perform a rotation, at a constant angular velocity, from a uniform superposition of all states to the solution state. This makes it possible to implement the two Hamiltonian-evolution algorithms on a conventional quantum circuit, while keeping the quadratic speedup of Grover's original algorithm. It also clarifies the link between the adiabatic search algorithm and Grover's algorithm

  17. Exploring the Relevance of Search Engines: An Overview of Google as a Case Study

    Directory of Open Access Journals (Sweden)

    Ricardo Beltrán-Alfonso

    2017-08-01

    Full Text Available The huge amount of data on the Internet and the diverse list of strategies used to try to link this information with relevant searches through Linked Data have generated a revolution in data treatment and its representation. Nevertheless, the conventional search engines like Google are kept as strategies with good reception to do search processes. The following article presents a study of the development and evolution of search engines, more specifically, to analyze the relevance of findings based on the number of results displayed in paging systems with Google as a case study. Finally, it is intended to contribute to indexing criteria in search results, based on an approach to Semantic Web as a stage in the evolution of the Web.

  18. Dark-matter QCD-axion searches

    International Nuclear Information System (INIS)

    Rosenberg, Leslie J

    2010-01-01

    The axion is a hypothetical elementary particle appearing in a simple and elegant extension to the Standard Model of particle physics that cancels otherwise huge CP-violating effects in QCD; this extension has a broken U(1) axial symmetry, where the resulting Goldstone Boson is the axion. A light axion of mass 10 -(6-3) eV (the so-called i nvisible axion ) would couple extraordinarily weakly to normal matter and radiation and would therefore be extremely difficult to detect in the laboratory. However, such an axion would be a compelling dark-matter candidate and is therefore a target of a number of searches. Compared to other dark-matter candidates, the plausible range of axion dark-matter couplings and masses is narrowly constrained. This restricted search space allows for 'definitive' searches, where non-observation would seriously impugn the dark-matter QCD-axion hypothesis. Axion searches employ a wide range of technologies and techniques, from astrophysical observations to laboratory electromagnetic signal detection. For some experiments, sensitivities are have reached likely dark-matter axion couplings and masses. This is a brief and selective overview of axion searches. With only very limited space, I briefly describe just two of the many experiments that are searching for dark-matter axions.

  19. Refining search terms for nanotechnology

    International Nuclear Information System (INIS)

    Porter, Alan L.; Youtie, Jan; Shapira, Philip; Schoeneck, David J.

    2008-01-01

    The ability to delineate the boundaries of an emerging technology is central to obtaining an understanding of the technology's research paths and commercialization prospects. Nowhere is this more relevant than in the case of nanotechnology (hereafter identified as 'nano') given its current rapid growth and multidisciplinary nature. (Under the rubric of nanotechnology, we also include nanoscience and nanoengineering.) Past efforts have utilized several strategies, including simple term search for the prefix nano, complex lexical and citation-based approaches, and bootstrapping techniques. This research introduces a modularized Boolean approach to defining nanotechnology which has been applied to several research and patenting databases. We explain our approach to downloading and cleaning data, and report initial results. Comparisons of this approach with other nanotechnology search formulations are presented. Implications for search strategy development and profiling of the nanotechnology field are discussed

  20. Refining search terms for nanotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Porter, Alan L. [Georgia Institute of Technology (United States); Youtie, Jan [Georgia Institute of Technology, Enterprise Innovation Institute (United States)], E-mail: jan.youtie@innovate.gatech.edu; Shapira, Philip [Georgia Institute of Technology (United States); Schoeneck, David J. [Search Technology, Inc. (United States)

    2008-05-15

    The ability to delineate the boundaries of an emerging technology is central to obtaining an understanding of the technology's research paths and commercialization prospects. Nowhere is this more relevant than in the case of nanotechnology (hereafter identified as 'nano') given its current rapid growth and multidisciplinary nature. (Under the rubric of nanotechnology, we also include nanoscience and nanoengineering.) Past efforts have utilized several strategies, including simple term search for the prefix nano, complex lexical and citation-based approaches, and bootstrapping techniques. This research introduces a modularized Boolean approach to defining nanotechnology which has been applied to several research and patenting databases. We explain our approach to downloading and cleaning data, and report initial results. Comparisons of this approach with other nanotechnology search formulations are presented. Implications for search strategy development and profiling of the nanotechnology field are discussed.

  1. Conditional Probability Modulates Visual Search Efficiency

    Directory of Open Access Journals (Sweden)

    Bryan eCort

    2013-10-01

    Full Text Available We investigated the effects of probability on visual search. Previous work has shown that people can utilize spatial and sequential probability information to improve target detection. We hypothesized that performance improvements from probability information would extend to the efficiency of visual search. Our task was a simple visual search in which the target was always present among a field of distractors, and could take one of two colors. The absolute probability of the target being either color was 0.5; however, the conditional probability – the likelihood of a particular color given a particular combination of two cues – varied from 0.1 to 0.9. We found that participants searched more efficiently for high conditional probability targets and less efficiently for low conditional probability targets, but only when they were explicitly informed of the probability relationship between cues and target color.

  2. Shaken, Not Steered: The Value of Shaking Up the Search Process

    NARCIS (Netherlands)

    Kumpulainen, S.; Huurdeman, H.

    2015-01-01

    The search engines of our times have brought ubiquitous access to information into the reach of nearly everyone. A wealth of information is just one click away, and streamlined search engines have become increasingly efficient at looking up information. However, the fact that it is simple to look up

  3. Curating the Web: Building a Google Custom Search Engine for the Arts

    Science.gov (United States)

    Hennesy, Cody; Bowman, John

    2008-01-01

    Google's first foray onto the web made search simple and results relevant. With its Co-op platform, Google has taken another step toward dramatically increasing the relevancy of search results, further adapting the World Wide Web to local needs. Google Custom Search Engine, a tool on the Co-op platform, puts one in control of his or her own search…

  4. Overview of the TREC 2014 Federated Web Search Track

    OpenAIRE

    Demeester, Thomas; Trieschnigg, Rudolf Berend; Nguyen, Dong-Phuong; Zhou, Ke; Hiemstra, Djoerd

    2014-01-01

    The TREC Federated Web Search track facilitates research in topics related to federated web search, by providing a large realistic data collection sampled from a multitude of online search engines. The FedWeb 2013 challenges of Resource Selection and Results Merging challenges are again included in FedWeb 2014, and we additionally introduced the task of vertical selection. Other new aspects are the required link between the Resource Selection and Results Merging, and the importance of diversi...

  5. Searching gravitational microlensing events in the galaxy spiral arms by EROS II

    International Nuclear Information System (INIS)

    Derue, Frederic

    1999-01-01

    The EROS II experiment is searching for microlensing events due to compact massive objects passing through the line-of-sight of luminous stars. These objects are candidates to explain the baryonic component of Dark Matter in our Galaxy. EROS II was dedicated to different lines-of-sight: Small and Large Magellanic Clouds, Galactic Centre and 4 directions towards the Spiral Arms of the Galaxy. This thesis presents the first search for microlensing towards these last lines-of-sight (about 9 million stars). Simple criteria based on the search for significant fluctuations allowed one to discover a low noise sample of 7 candidates to the microlensing effect, with an average timescale of 50 days. A detailed analysis of the light curve of one candidate allows us to give a confidence interval on its mass 2.7 x 10 -3 0 0 = 50 ± 3 days. To improve the knowledge of the distance of the target stars, we have combined observations of EROS II with bibliographic sources on associations of stars linked with the spiral arm features, and we have developed a program to find variable stars. Ten cepheids have thus been found. Distances obtained with different methods are in rough agreement with each other. The average optical depth measured towards the four directions is τ-bar = 0.45 0.11 +0.23 x 10 -6 . It is compatible with expectations from simple galactic models. The long duration of most events favours interpretation of lensing by objects belonging to the disk instead of the halo. It also seems that some events due to bulge lenses have influenced measurements towards the line-of-sight which is closest to the Galactic Centre. Observation continue towards spiral arms. More accurate measurements should be obtained with increase of statistics, allowing one to estimate the disk contribution to the optical depth towards the bulge and the Magellanic Clouds. (author)

  6. Linked Data: what does it offer Earth Sciences?

    Science.gov (United States)

    Cox, Simon; Schade, Sven

    2010-05-01

    'Linked Data' is a current buzz-phrase promoting access to various forms of data on the internet. It starts from the two principles that have underpinned the architecture and scalability of the World Wide Web: 1. Universal Resource Identifiers - using the http protocol which is supported by the DNS system. 2. Hypertext - in which URIs of related resources are embedded within a document. Browsing is the key mode of interaction, with traversal of links between resources under control of the client. Linked Data also adds, or re-emphasizes: • Content negotiation - whereby the client uses http headers to tell the service what representation of a resource is acceptable, • Semantic Web principles - formal semantics for links, following the RDF data model and encoding, and • The 'mashup' effect - in which original and unexpected value may emerge from reuse of data, even if published in raw or unpolished form. Linked Data promotes typed links to all kinds of data, so is where the semantic web meets the 'deep web', i.e. resources which may be accessed using web protocols, but are in representations not indexed by search engines. Earth sciences are data rich, but with a strong legacy of specialized formats managed and processed by disconnected applications. However, most contemporary research problems require a cross-disciplinary approach, in which the heterogeneity resulting from that legacy is a significant challenge. In this context, Linked Data clearly has much to offer the earth sciences. But, there are some important questions to answer. What is a resource? Most earth science data is organized in arrays and databases. A subset useful for a particular study is usually identified by a parameterized query. The Linked Data paradigm emerged from the world of documents, and will often only resolve data-sets. It is impractical to create even nested navigation resources containing links to all potentially useful objects or subsets. From the viewpoint of human user

  7. Interchip link system using an optical wiring method.

    Science.gov (United States)

    Cho, In-Kui; Ryu, Jin-Hwa; Jeong, Myung-Yung

    2008-08-15

    A chip-scale optical link system is presented with a transmitter/receiver and optical wire link. The interchip link system consists of a metal optical bench, a printed circuit board module, a driver/receiver integrated circuit, a vertical cavity surface-emitting laser/photodiode array, and an optical wire link composed of plastic optical fibers (POFs). We have developed a downsized POF and an optical wiring method that allows on-site installation with a simple annealing as optical wiring technologies for achieving high-density optical interchip interconnection within such devices. Successful data transfer measurements are presented.

  8. Optimizing Event Selection with the Random Grid Search

    Energy Technology Data Exchange (ETDEWEB)

    Bhat, Pushpalatha C. [Fermilab; Prosper, Harrison B. [Florida State U.; Sekmen, Sezen [Kyungpook Natl. U.; Stewart, Chip [Broad Inst., Cambridge

    2017-06-29

    The random grid search (RGS) is a simple, but efficient, stochastic algorithm to find optimal cuts that was developed in the context of the search for the top quark at Fermilab in the mid-1990s. The algorithm, and associated code, have been enhanced recently with the introduction of two new cut types, one of which has been successfully used in searches for supersymmetry at the Large Hadron Collider. The RGS optimization algorithm is described along with the recent developments, which are illustrated with two examples from particle physics. One explores the optimization of the selection of vector boson fusion events in the four-lepton decay mode of the Higgs boson and the other optimizes SUSY searches using boosted objects and the razor variables.

  9. Searching for supersymmetry at the LHC

    CERN Multimedia

    CERN. Geneva. Audiovisual Unit; Ridolfi, Giovanni

    2003-01-01

    We will review the general motivations for proposing non-standard descriptions of fundamental interactions. We will give a simple and pedagogical presentation of the theoretical foundations of Supersymmetry, and we will describe the main features of a realistic supersymmetric extension of the Standard Model. We will present the phenomenology expected in several motivated scenarios. We will then review the present status of the experimental searches for Supersymmetry at LEP and Tevatron, and discuss prospects at future machines with emphasis on the LHC. We will outline the search strategies and the analysis methods, and compare the sensitivity and reach of the various machines.

  10. Blind links, a big challenge in the linked data idea: Analysis of Persian Subject Headings

    Directory of Open Access Journals (Sweden)

    Atefeh Sharif

    2014-12-01

    Full Text Available In this survey, Linked data concept as exposing, sharing, and connecting pieces of data, information, and knowledge on the Semantic Web and some potential problems in converting Persian subject headings (PSHs Records into linked data were discussed. A data set (11233 records of PSHs was searched in three information retrieval systems including National Library of Iran (NLI online catalog, Library of Congress (LC online catalog and NOSA books. Correct links between Persian and English subject headings in the 9519 common records of two catalogs were recorded. The results indicate that the links between Persian and English subjects in 20% of records were failed. The maximum error was associated with the anonymous databases (6/7 % in NLI online catalog. It is recommended to preprocess the PSHs records before any conversion projects. It seems that, during the preprocessing, the potential errors could be identified and corrected.

  11. Viking mission and the search for life on Mars

    International Nuclear Information System (INIS)

    Klein, H.P.

    1979-01-01

    Results of the Viking experiments to search for life on Mars are reviewed. Search for metabolic processes was made with a pyrolytic release experiment which required synthesis of organic material from CO or CO 2 . A gas exchange experiment looked for the production of oxidized and reduced gases. The labeled release experiment required decomposition of simple organic molecules with the release of a carbon gas. Results and their implications are discussed

  12. The Gigabit Link Interface Board (GLIB), a flexible system for the evaluation and use of GBT-based optical links

    CERN Document Server

    Vichoudis, P; Vasey, F; Joos, M; Hansen, M; Haas, S; Baron, S

    2010-01-01

    The Gigabit Link Interface Board (GLIB) is an evaluation platform and an easy entry point for users of high speed optical links in high energy physics experiments. Its intended use ranges from optical link evaluation in the laboratory to control, triggering and data acquisition from remote modules in beam or irradiation tests. The GLIB is an FPGA-based Advanced Mezzanine Card (AMC) conceived to serve a small and simple system residing either inside a Micro Telecommunications Computing Architecture (mu TCA) crate, or on a bench with a link to a PC. This paper presents the architecture of the GLIB, its features as well as examples of its use in different setups.

  13. Visual search deficits in amblyopia.

    Science.gov (United States)

    Tsirlin, Inna; Colpa, Linda; Goltz, Herbert C; Wong, Agnes M F

    2018-04-01

    Amblyopia is a neurodevelopmental disorder defined as a reduction in visual acuity that cannot be corrected by optical means. It has been associated with low-level deficits. However, research has demonstrated a link between amblyopia and visual attention deficits in counting, tracking, and identifying objects. Visual search is a useful tool for assessing visual attention but has not been well studied in amblyopia. Here, we assessed the extent of visual search deficits in amblyopia using feature and conjunction search tasks. We compared the performance of participants with amblyopia (n = 10) to those of controls (n = 12) on both feature and conjunction search tasks using Gabor patch stimuli, varying spatial bandwidth and orientation. To account for the low-level deficits inherent in amblyopia, we measured individual contrast and crowding thresholds and monitored eye movements. The display elements were then presented at suprathreshold levels to ensure that visibility was equalized across groups. There was no performance difference between groups on feature search, indicating that our experimental design controlled successfully for low-level amblyopia deficits. In contrast, during conjunction search, median reaction times and reaction time slopes were significantly larger in participants with amblyopia compared with controls. Amblyopia differentially affects performance on conjunction visual search, a more difficult task that requires feature binding and possibly the involvement of higher-level attention processes. Deficits in visual search may affect day-to-day functioning in people with amblyopia.

  14. Shuttle Planning for Link Closures in Urban Public Transport Networks

    NARCIS (Netherlands)

    van der Hurk, E.; Koutsopoulos, H.; Wilson, N.H.M.; Kroon, L.G.; Maroti, G.

    2016-01-01

    Urban public transport systems must periodically close certain links for maintenance, which can have significant effects on the service provided to passengers. In practice, the effects of closures are mitigated by replacing the closed links with a simple shuttle service. However, alternative shuttle

  15. On local search for bi-objective knapsack problems.

    Science.gov (United States)

    Liefooghe, Arnaud; Paquete, Luís; Figueira, José Rui

    2013-01-01

    In this article, a local search approach is proposed for three variants of the bi-objective binary knapsack problem, with the aim of maximizing the total profit and minimizing the total weight. First, an experimental study on a given structural property of connectedness of the efficient set is conducted. Based on this property, a local search algorithm is proposed and its performance is compared to exact algorithms in terms of runtime and quality metrics. The experimental results indicate that this simple local search algorithm is able to find a representative set of optimal solutions in most of the cases, and in much less time than exact algorithms.

  16. Linking Quality and Spending to Measure Value for People with Serious Illness

    Science.gov (United States)

    Rodgers, Phillip E.

    2018-01-01

    Abstract Background: Healthcare payment is rapidly evolving to reward value by measuring and paying for quality and spending performance. Rewarding value for the care of seriously ill patients presents unique challenges. Objective: To evaluate the state of current efforts to measure and reward value for the care of seriously ill patients. Design: We performed a PubMed search of articles related to (1) measures of spending for people with serious illness and (2) linking spending and quality measures and rewarding performance for the care of people with serious illness. We limited our search to U.S.-based studies published in English between January 1, 1960, and March 31, 2017. We supplemented this search by identifying public programs and other known initiatives that linked quality and spending for the seriously ill and extracted key program elements. Results: Our search related to linking spending and quality measures and rewarding performance for the care of people with serious illness yielded 277 articles. We identified three current public programs that currently link measures of quality and spending—or are likely to within the next few years—the Oncology Care Model; the Comprehensive End-Stage Renal Disease Model; and Home Health Value-Based Purchasing. Models that link quality and spending consist of four core components: (1) measuring quality, (2) measuring spending, (3) the payment adjustment model, and (4) the linking/incentive model. We found that current efforts to reward value for seriously ill patients are targeted for specific patient populations, do not broadly encourage the use of palliative care, and have not closely aligned quality and spending measures related to palliative care. Conclusions: We develop recommendations for policymakers and stakeholders about how measures of spending and quality can be balanced in value-based payment programs. PMID:29091529

  17. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice.

    Science.gov (United States)

    Riva, Silvia; Monti, Marco; Antonietti, Alessandro

    2011-01-01

    Over-the-counter (OTC) drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions. This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts. By analyzing 70 subjects' information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants' choices in a virtual environment. We found that subjects' information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects' decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects' decisions. The current emphasis in health care is to shift some responsibility onto the consumer through expansion of self medication. To know which cognitive mechanisms are behind the choice of OTC drugs is becoming a relevant purpose of current medical education. These findings have implications both for the validity of simple heuristics describing information searches in the field of OTC drug choices and for current medical education, which has to prepare competent health

  18. The LAILAPS Search Engine: Relevance Ranking in Life Science Databases

    Directory of Open Access Journals (Sweden)

    Lange Matthias

    2010-06-01

    Full Text Available Search engines and retrieval systems are popular tools at a life science desktop. The manual inspection of hundreds of database entries, that reflect a life science concept or fact, is a time intensive daily work. Hereby, not the number of query results matters, but the relevance does. In this paper, we present the LAILAPS search engine for life science databases. The concept is to combine a novel feature model for relevance ranking, a machine learning approach to model user relevance profiles, ranking improvement by user feedback tracking and an intuitive and slim web user interface, that estimates relevance rank by tracking user interactions. Queries are formulated as simple keyword lists and will be expanded by synonyms. Supporting a flexible text index and a simple data import format, LAILAPS can easily be used both as search engine for comprehensive integrated life science databases and for small in-house project databases.

  19. Search Results | Page 7 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2013-11-06

    Nov 6, 2013 ... Mobile Nav Footer Links. Careers · Contact Us · Subscribe · Unsubscribe · Copyright · Open Access Policy · Privacy Policy · Research Ethics · Transparency · Website/Usage. Search. Home · South of Sahara; Cameroon ...

  20. The effect of query complexity on Web searching results

    Directory of Open Access Journals (Sweden)

    B.J. Jansen

    2000-01-01

    Full Text Available This paper presents findings from a study of the effects of query structure on retrieval by Web search services. Fifteen queries were selected from the transaction log of a major Web search service in simple query form with no advanced operators (e.g., Boolean operators, phrase operators, etc. and submitted to 5 major search engines - Alta Vista, Excite, FAST Search, Infoseek, and Northern Light. The results from these queries became the baseline data. The original 15 queries were then modified using the various search operators supported by each of the 5 search engines for a total of 210 queries. Each of these 210 queries was also submitted to the applicable search service. The results obtained were then compared to the baseline results. A total of 2,768 search results were returned by the set of all queries. In general, increasing the complexity of the queries had little effect on the results with a greater than 70% overlap in results, on average. Implications for the design of Web search services and directions for future research are discussed.

  1. Optimal intermittent search strategies

    International Nuclear Information System (INIS)

    Rojo, F; Budde, C E; Wio, H S

    2009-01-01

    We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion

  2. Extracting Macroscopic Information from Web Links.

    Science.gov (United States)

    Thelwall, Mike

    2001-01-01

    Discussion of Web-based link analysis focuses on an evaluation of Ingversen's proposed external Web Impact Factor for the original use of the Web, namely the interlinking of academic research. Studies relationships between academic hyperlinks and research activities for British universities and discusses the use of search engines for Web link…

  3. Annual variation in Internet keyword searches: Linking dieting interest to obesity and negative health outcomes.

    Science.gov (United States)

    Markey, Patrick M; Markey, Charlotte N

    2013-07-01

    This study investigated the annual variation in Internet searches regarding dieting. Time-series analysis was first used to examine the annual trends of Google keyword searches during the past 7 years for topics related to dieting within the United States. The results indicated that keyword searches for dieting fit a consistent 12-month linear model, peaking in January (following New Year's Eve) and then linearly decreasing until surging again the following January. Additional state-level analyses revealed that the size of the December-January dieting-related keyword surge was predictive of both obesity and mortality rates due to diabetes, heart disease, and stroke.

  4. A New Approximate Chimera Donor Cell Search Algorithm

    Science.gov (United States)

    Holst, Terry L.; Nixon, David (Technical Monitor)

    1998-01-01

    The objectives of this study were to develop chimera-based full potential methodology which is compatible with overflow (Euler/Navier-Stokes) chimera flow solver and to develop a fast donor cell search algorithm that is compatible with the chimera full potential approach. Results of this work included presenting a new donor cell search algorithm suitable for use with a chimera-based full potential solver. This algorithm was found to be extremely fast and simple producing donor cells as fast as 60,000 per second.

  5. Toward two-dimensional search engines

    International Nuclear Information System (INIS)

    Ermann, L; Shepelyansky, D L; Chepelianskii, A D

    2012-01-01

    We study the statistical properties of various directed networks using ranking of their nodes based on the dominant vectors of the Google matrix known as PageRank and CheiRank. On average PageRank orders nodes proportionally to a number of ingoing links, while CheiRank orders nodes proportionally to a number of outgoing links. In this way, the ranking of nodes becomes two dimensional which paves the way for the development of two-dimensional search engines of a new type. Statistical properties of information flow on the PageRank–CheiRank plane are analyzed for networks of British, French and Italian universities, Wikipedia, Linux Kernel, gene regulation and other networks. A special emphasis is done for British universities networks using the large database publicly available in the UK. Methods of spam links control are also analyzed. (paper)

  6. Search Results | Page 843 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 8421 - 8430 of 8489 ... IDRC permits reading, downloading, copying, redistributing, printing, linking and searching, for non-commercial or academic purposes, of any of its content, provided that credit and reference is given to IDRC and the original source page and, in the. Webpage.

  7. Discovery of undefined protein cross-linking chemistry: a comprehensive methodology utilizing 18O-labeling and mass spectrometry.

    Science.gov (United States)

    Liu, Min; Zhang, Zhongqi; Zang, Tianzhu; Spahr, Chris; Cheetham, Janet; Ren, Da; Zhou, Zhaohui Sunny

    2013-06-18

    Characterization of protein cross-linking, particularly without prior knowledge of the chemical nature and site of cross-linking, poses a significant challenge, because of their intrinsic structural complexity and the lack of a comprehensive analytical approach. Toward this end, we have developed a generally applicable workflow-XChem-Finder-that involves four stages: (1) detection of cross-linked peptides via (18)O-labeling at C-termini; (2) determination of the putative partial sequences of each cross-linked peptide pair using a fragment ion mass database search against known protein sequences coupled with a de novo sequence tag search; (3) extension to full sequences based on protease specificity, the unique combination of mass, and other constraints; and (4) deduction of cross-linking chemistry and site. The mass difference between the sum of two putative full-length peptides and the cross-linked peptide provides the formulas (elemental composition analysis) for the functional groups involved in each cross-linking. Combined with sequence restraint from MS/MS data, plausible cross-linking chemistry and site were inferred, and ultimately confirmed, by matching with all data. Applying our approach to a stressed IgG2 antibody, 10 cross-linked peptides were discovered and found to be connected via thioethers originating from disulfides at locations that had not been previously recognized. Furthermore, once the cross-link chemistry was revealed, a targeted cross-link search yielded 4 additional cross-linked peptides that all contain the C-terminus of the light chain.

  8. Medial temporal lobe damage impairs representation of simple stimuli

    Directory of Open Access Journals (Sweden)

    David E Warren

    2010-05-01

    Full Text Available Medial temporal lobe damage in humans is typically thought to produce a circumscribed impairment in the acquisition of new enduring memories, but recent reports have documented deficits even in short-term maintenance. We examined possible maintenance deficits in a population of medial temporal lobe amnesics, with the goal of characterizing their impairments as either representational drift or outright loss of representation over time. Patients and healthy comparisons performed a visual search task in which the similarity of various lures to a target was varied parametrically. Stimuli were simple shapes varying along one of several visual dimensions. The task was performed in two conditions, one presenting a sample target simultaneously with the search array and the other imposing a delay between sample and array. Eye-movement data collected during search revealed that the duration of fixations to items varied with lure-target similarity for all participants, i.e., fixations were longer for items more similar to the target. In the simultaneous condition, patients and comparisons exhibited an equivalent effect of similarity on fixation durations. However, imposing a delay modulated the effect differently for the two groups: in comparisons, fixation duration to similar items was exaggerated; in patients, the original effect was diminished. These findings indicate that medial temporal lobe lesions subtly impair short-term maintenance of even simple stimuli, with performance reflecting not the complete loss of the maintained representation but rather a degradation or progressive drift of the representation over time.

  9. Optimal intermittent search strategies

    Energy Technology Data Exchange (ETDEWEB)

    Rojo, F; Budde, C E [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, X5000HUA Cordoba (Argentina); Wio, H S [Instituto de Fisica de Cantabria, Universidad de Cantabria and CSIC E-39005 Santander (Spain)

    2009-03-27

    We study the search kinetics of a single fixed target by a set of searchers performing an intermittent random walk, jumping between different internal states. Exploiting concepts of multi-state and continuous-time random walks we have calculated the survival probability of a target up to time t, and have 'optimized' (minimized) it with regard to the transition probability among internal states. Our model shows that intermittent strategies always improve target detection, even for simple diffusion states of motion.

  10. PubMed searches: overview and strategies for clinicians.

    Science.gov (United States)

    Lindsey, Wesley T; Olin, Bernie R

    2013-04-01

    PubMed is a biomedical and life sciences database maintained by a division of the National Library of Medicine known as the National Center for Biotechnology Information (NCBI). It is a large resource with more than 5600 journals indexed and greater than 22 million total citations. Searches conducted in PubMed provide references that are more specific for the intended topic compared with other popular search engines. Effective PubMed searches allow the clinician to remain current on the latest clinical trials, systematic reviews, and practice guidelines. PubMed continues to evolve by allowing users to create a customized experience through the My NCBI portal, new arrangements and options in search filters, and supporting scholarly projects through exportation of citations to reference managing software. Prepackaged search options available in the Clinical Queries feature also allow users to efficiently search for clinical literature. PubMed also provides information regarding the source journals themselves through the Journals in NCBI Databases link. This article provides an overview of the PubMed database's structure and features as well as strategies for conducting an effective search.

  11. Search Results | Page 846 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 8451 - 8460 of 8518 ... Agriculture and Food Security ... IDRC permits reading, downloading, copying, redistributing, printing, linking and searching, for non-commercial or academic purposes, of any of its content, provided that credit and reference is given ... IDRC funds many research projects that raise ethical issues.

  12. Models for stiffening in cross-linked biopolymer networks : A comparative study

    NARCIS (Netherlands)

    van Dillen, T.; Onck, P. R.; Van der Giessen, E.

    In a recent publication, we studied the mechanical stiffening behavior in two-dimensional (2D) cross-linked networks of semiflexible biopolymer filaments under simple shear [Onck, P.R., Koeman, T., Van Dillen, T., Van der Giessen, E., 2005. Alternative explanation of stiffening in cross-linked

  13. X-linked hypophosphatemia. A phenotype in search of a cause.

    Science.gov (United States)

    Tenenhouse, H S; Scriver, C R

    1992-05-01

    XLH is an important disease, it is the subject of several classic articles in the medical sciences (Scriver et al., 1991), and it has been an important stimulus to study renal hypophosphatemias and how they are involved in rickets and osteomalacia (Scriver, 1974; Scriver and Tenenhouse, 1991). Renal transport is the major determinant of phosphate homeostasis in mammals and it is unlikely that this important biochemical parameter would have been left by evolution to a single renal transport system. Together physiologists and geneticists found that the mammalian kidney has several gene products dedicated to phosphate transport. That has implications for biochemists in search of a membrane protein to clone and explain XLH, for example. Let us suppose the transporter affected in XLH is cloned. Will it be the product of the XLH (or Hyp or Gy) locus? One will not know until the transporter gene is mapped. There is no question of the X-chromosome locus product being protein kinase C for example, since it maps to autosomes. But where does one start in the search for the X-chromosome locus? With the elusive putative diffusible factor or with the transporter, or perhaps with an enzyme in vitamin D hormone metabolism? Which goes to say that it is necessary to know the phenotype to arrive at the right locus. Or is it? Sufficient physical mapping of region Xp22.31-p21.3 will eventually lead to positional cloning of the Hyp gene. What will it be?(ABSTRACT TRUNCATED AT 250 WORDS)

  14. LIVIVO - the Vertical Search Engine for Life Sciences.

    Science.gov (United States)

    Müller, Bernd; Poley, Christoph; Pössel, Jana; Hagelstein, Alexandra; Gübitz, Thomas

    2017-01-01

    The explosive growth of literature and data in the life sciences challenges researchers to keep track of current advancements in their disciplines. Novel approaches in the life science like the One Health paradigm require integrated methodologies in order to link and connect heterogeneous information from databases and literature resources. Current publications in the life sciences are increasingly characterized by the employment of trans-disciplinary methodologies comprising molecular and cell biology, genetics, genomic, epigenomic, transcriptional and proteomic high throughput technologies with data from humans, plants, and animals. The literature search engine LIVIVO empowers retrieval functionality by incorporating various literature resources from medicine, health, environment, agriculture and nutrition. LIVIVO is developed in-house by ZB MED - Information Centre for Life Sciences. It provides a user-friendly and usability-tested search interface with a corpus of 55 Million citations derived from 50 databases. Standardized application programming interfaces are available for data export and high throughput retrieval. The search functions allow for semantic retrieval with filtering options based on life science entities. The service oriented architecture of LIVIVO uses four different implementation layers to deliver search services. A Knowledge Environment is developed by ZB MED to deal with the heterogeneity of data as an integrative approach to model, store, and link semantic concepts within literature resources and databases. Future work will focus on the exploitation of life science ontologies and on the employment of NLP technologies in order to improve query expansion, filters in faceted search, and concept based relevancy rankings in LIVIVO.

  15. A proposed model of psychodynamic psychotherapy linked to Erik Erikson's eight stages of psychosocial development.

    Science.gov (United States)

    Knight, Zelda Gillian

    2017-09-01

    Just as Freud used stages of psychosexual development to ground his model of psychoanalysis, it is possible to do the same with Erik Erikson's stages of development with regards to a model of psychodynamic psychotherapy. This paper proposes an eight-stage model of psychodynamic psychotherapy linked to Erik Erikson's eight stages of psychosocial development. Various suggestions are offered. One such suggestion is that as each of Erikson's developmental stages is triggered by a crisis, in therapy it is triggered by the client's search. The resolution of the search often leads to the development of another search, which implies that the therapy process comprises a series of searches. This idea of a series of searches and resolutions leads to the understanding that identity is developmental and therapy is a space in which a new sense of identity may emerge. The notion of hope is linked to Erikson's stage of Basic Trust and the proposed model of therapy views hope and trust as essential for the therapy process. Two clinical vignettes are offered to illustrate these ideas. Psychotherapy can be approached as an eight-stage process and linked to Erikson's eight stages model of development. Psychotherapy may be viewed as a series of searches and thus as a developmental stage resolution process, which leads to the understanding that identity is ongoing throughout the life span. Copyright © 2017 John Wiley & Sons, Ltd.

  16. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice

    Science.gov (United States)

    Riva, Silvia; Monti, Marco; Antonietti, Alessandro

    2011-01-01

    Introduction Over-the-counter (OTC) drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions. Purpose This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts. Subjects and methods By analyzing 70 subjects’ information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants’ choices in a virtual environment. Results We found that subjects’ information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects’ decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects’ decisions. Conclusion The current emphasis in health care is to shift some responsibility onto the consumer through expansion of self medication. To know which cognitive mechanisms are behind the choice of OTC drugs is becoming a relevant purpose of current medical education. These findings have implications both for the validity of simple heuristics describing information searches in the field of OTC drug choices and

  17. Ant-based extraction of rules in simple decision systems over ontological graphs

    Directory of Open Access Journals (Sweden)

    Pancerz Krzysztof

    2015-06-01

    Full Text Available In the paper, the problem of extraction of complex decision rules in simple decision systems over ontological graphs is considered. The extracted rules are consistent with the dominance principle similar to that applied in the dominancebased rough set approach (DRSA. In our study, we propose to use a heuristic algorithm, utilizing the ant-based clustering approach, searching the semantic spaces of concepts presented by means of ontological graphs. Concepts included in the semantic spaces are values of attributes describing objects in simple decision systems

  18. Genetic studies and a search for molecular markers that are linked ...

    African Journals Online (AJOL)

    Molecular markers that are linked to witchweed resistance can expedite the development of resistant cultivars through adoption of appropriate markerassisted selection (MAS) strategies. The objectives of this investigation were to study the inheritance or low germination stimulant (lgs) production in cultivar SAR 29 and to ...

  19. Efficient search by optimized intermittent random walks

    International Nuclear Information System (INIS)

    Oshanin, Gleb; Lindenberg, Katja; Wio, Horacio S; Burlatsky, Sergei

    2009-01-01

    We study the kinetics for the search of an immobile target by randomly moving searchers that detect it only upon encounter. The searchers perform intermittent random walks on a one-dimensional lattice. Each searcher can step on a nearest neighbor site with probability α or go off lattice with probability 1 - α to move in a random direction until it lands back on the lattice at a fixed distance L away from the departure point. Considering α and L as optimization parameters, we seek to enhance the chances of successful detection by minimizing the probability P N that the target remains undetected up to the maximal search time N. We show that even in this simple model, a number of very efficient search strategies can lead to a decrease of P N by orders of magnitude upon appropriate choices of α and L. We demonstrate that, in general, such optimal intermittent strategies are much more efficient than Brownian searches and are as efficient as search algorithms based on random walks with heavy-tailed Cauchy jump-length distributions. In addition, such intermittent strategies appear to be more advantageous than Levy-based ones in that they lead to more thorough exploration of visited regions in space and thus lend themselves to parallelization of the search processes.

  20. Helically linked mirror arrangement

    International Nuclear Information System (INIS)

    Ranjan, P.

    1986-08-01

    A scheme is described for helical linking of mirror sections, which endeavors to combine the better features of toroidal and mirror devices by eliminating the longitudinal loss of mirror machines, having moderately high average β and steady state operation. This scheme is aimed at a device, with closed magnetic surfaces having rotational transform for equilibrium, one or more axisymmetric straight sections for reduced radial loss, a simple geometrical axis for the links and an overall positive magnetic well depth for stability. We start by describing several other attempts at linking of mirror sections, made both in the past and the present. Then a description of our helically linked mirror scheme is given. This example has three identical straight sections connected by three sections having helical geometric axes. A theoretical analysis of the magnetic field and single-particle orbits in them leads to the conclusion that most of the passing particles would be confined in the device and they would have orbits independent of pitch angle under certain conditions. Numerical results are presented, which agree well with the theoretical results as far as passing particle orbits are concerned

  1. The use of magnetic susceptibility as a forensic search tool.

    Science.gov (United States)

    Pringle, Jamie K; Giubertoni, Matteo; Cassidy, Nigel J; Wisniewski, Kristopher D; Hansen, James D; Linford, Neil T; Daniels, Rebecca M

    2015-01-01

    There are various techniques available for forensic search teams to employ to successfully detect a buried object. Near-surface geophysical search methods have been dominated by ground penetrating radar but recently other techniques, such as electrical resistivity, have become more common. This paper discusses magnetic susceptibility as a simple surface search tool illustrated by various research studies. These suggest magnetic susceptibility to be a relatively low cost, quick and effective tool, compared to other geophysical methods, to determine disturbed ground above buried objects and burnt surface remains in a variety of soil types. Further research should collect datasets over objects of known burial ages for comparison purposes and used in forensic search cases to validate the technique. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  2. Buffer-Aided Relaying with Adaptive Link Selection

    DEFF Research Database (Denmark)

    Zlatanov, Nikola; Schober, Robert; Popovski, Petar

    2013-01-01

    In this paper, we consider a simple network consisting of a source, a half-duplex decode-and-forward relay, and a destination. We propose a new relaying protocol employing adaptive link selection, i.e., in any given time slot, based on the channel state information of the source-relay and the relay......-destination link a decision is made whether the source or the relay transmits. In order to avoid data loss at the relay, adaptive link selection requires the relay to be equipped with a buffer such that data can be queued until the relay-destination link is selected for transmission. We study both delay......-constrained and delay-unconstrained transmission. For the delay-unconstrained case, we characterize the optimal link selection policy, derive the corresponding throughput, and develop an optimal power allocation scheme. For the delay-constrained case, we propose to starve the buffer of the relay by choosing...

  3. Autonomous change of behavior for environmental context: An intermittent search model with misunderstanding search pattern

    Science.gov (United States)

    Murakami, Hisashi; Gunji, Yukio-Pegio

    2017-07-01

    Although foraging patterns have long been predicted to optimally adapt to environmental conditions, empirical evidence has been found in recent years. This evidence suggests that the search strategy of animals is open to change so that animals can flexibly respond to their environment. In this study, we began with a simple computational model that possesses the principal features of an intermittent strategy, i.e., careful local searches separated by longer steps, as a mechanism for relocation, where an agent in the model follows a rule to switch between two phases, but it could misunderstand this rule, i.e., the agent follows an ambiguous switching rule. Thanks to this ambiguity, the agent's foraging strategy can continuously change. First, we demonstrate that our model can exhibit an optimal change of strategy from Brownian-type to Lévy-type depending on the prey density, and we investigate the distribution of time intervals for switching between the phases. Moreover, we show that the model can display higher search efficiency than a correlated random walk.

  4. Search Results | Page 178 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... 100 Apply RESEARCH NETWORKS filter · Internet 95 Apply Internet filter · ACCESS TO INFORMATION 82 Apply ACCESS ... Mainstreaming gender issues in livestock research ... Examining the links between livestock ownership, gender, and food security ... But in Dakar, the capital of Senegal, things are not so simple.

  5. Simple measurement-based admission control for DiffServ access networks

    Science.gov (United States)

    Lakkakorpi, Jani

    2002-07-01

    In order to provide good Quality of Service (QoS) in a Differentiated Services (DiffServ) network, a dynamic admission control scheme is definitely needed as an alternative to overprovisioning. In this paper, we present a simple measurement-based admission control (MBAC) mechanism for DiffServ-based access networks. Instead of using active measurements only or doing purely static bookkeeping with parameter-based admission control (PBAC), the admission control decisions are based on bandwidth reservations and periodically measured & exponentially averaged link loads. If any link load on the path between two endpoints is over the applicable threshold, access is denied. Link loads are periodically sent to Bandwidth Broker (BB) of the routing domain, which makes the admission control decisions. The information needed in calculating the link loads is retrieved from the router statistics. The proposed admission control mechanism is verified through simulations. Our results prove that it is possible to achieve very high bottleneck link utilization levels and still maintain good QoS.

  6. Correlation among electronegativity, cation polarizability, optical basicity and single bond strength of simple oxides

    Energy Technology Data Exchange (ETDEWEB)

    Dimitrov, Vesselin, E-mail: vesselin@uctm.edu [Department of Silicate Technology, University of Chemical Technology and Metallurgy, 8, Kl. Ohridski Blvd., Sofia 1756 (Bulgaria); Komatsu, Takayuki, E-mail: komatsu@mst.nagaokaut.ac.jp [Department of Materials Science and Technology, Nagaoka University of Technology, 1603-1 Kamitomioka-cho, Nagaoka 940-2188 (Japan)

    2012-12-15

    A suitable relationship between free-cation polarizability and electronegativity of elements in different valence states and with the most common coordination numbers has been searched on the basis of the similarity in physical nature of both quantities. In general, the cation polarizability increases with decreasing element electronegativity. A systematic periodic change in the polarizability against the electronegativity has been observed in the isoelectronic series. It has been found that generally the optical basicity increases and the single bond strength of simple oxides decreases with decreasing the electronegativity. The observed trends have been discussed on the basis of electron donation ability of the oxide ions and type of chemical bonding in simple oxides. - Graphical abstract: This figure shows the single bond strength of simple oxides as a function of element electronegativity. A remarkable correlation exists between these independently obtained quantities. High values of electronegativity correspond to high values of single bond strength and vice versa. It is obvious that the observed trend in this figure is closely related to the type of chemical bonding in corresponding oxide. Highlights: Black-Right-Pointing-Pointer A suitable relationship between free-cation polarizability and electronegativity of elements was searched. Black-Right-Pointing-Pointer The cation polarizability increases with decreasing element electronegativity. Black-Right-Pointing-Pointer The single bond strength of simple oxides decreases with decreasing the electronegativity. Black-Right-Pointing-Pointer The observed trends were discussed on the basis of type of chemical bonding in simple oxides.

  7. Mapping queries to the Linking Open Data cloud: a case study using DBpedia

    NARCIS (Netherlands)

    Meij, E.; Bron, M.; Hollink, L.; Huurnink, B.; de Rijke, M.

    2011-01-01

    We introduce the task of mapping search engine queries to DBpedia, a major linking hub in the Linking Open Data cloud. We propose and compare various methods for addressing this task, using a mixture of information retrieval and machine learning techniques. Specifically, we present a supervised

  8. Polygons of global undersea features for geographic searches

    Science.gov (United States)

    Hartwell, Stephen R.; Wingfield, Dana K.; Allwardt, Alan O.; Lightsom, Frances L.; Wong, Florence L.

    2018-01-01

    A shapefile of 311 undersea features from all major oceans and seas has been created as an aid for retrieving georeferenced information resources. Geospatial information systems with the capability to search user-defined, polygonal geographic areas will be able to utilize this shapefile or secondary products derived from it, such as linked data based on well-known text representations of the individual polygons within the shapefile. Version 1.1 of this report also includes a linked data representation of 299 of these features and their spatial extents.

  9. Determination of histamine in Iranian cheese using enzyme-linked ...

    African Journals Online (AJOL)

    john

    enzyme-linked immunosorbent assay (ELISA) method. Mojtaba ... Histamine is a simple chemical substance created during processing of the amine acid histidine. Histamine is also an .... Institute of environment Health and Forensic. Sciences ...

  10. Binaural Sound Reduces Reaction Time in a Virtual Reality Search Task

    DEFF Research Database (Denmark)

    Høeg, Emil Rosenlund; Gerry, Lynda; Thomsen, Lui Albæk

    2017-01-01

    Salient features in a visual search task can direct attention and increase competency on these tasks. Simple cues, such as color change in a salient feature, called the "pop-out effect" can increase task solving efficiency [6]. Previous work has shown that nonspatial auditory signals temporally...... synched with a pop-out effect can improve reaction time in a visual search task, called the "pip and pop effect" [14]. This paper describes a within-group study on the effect of audiospatial attention in virtual reality given a 360-degree visual search. Three cue conditions were compared (no sound, stereo...

  11. Report on the Second Workshop on Supporting Complex Search Tasks : CHIIR 2017 Workshop Report

    NARCIS (Netherlands)

    Koolen, M.; Kamps, J.; Bogers, T.; Belkin, N.; Kelly, D.; Yilmaz, E.

    There is broad consensus in the field of IR that search is complex in many use cases and applications, both on the Web and in domain-specific collections, and both in our professional and in our daily life. Yet our understanding of complex search tasks, in comparison to simple look up tasks, is

  12. Linking of uniform random polygons in confined spaces

    International Nuclear Information System (INIS)

    Arsuaga, J; Blackstone, T; Diao, Y; Karadayi, E; Saito, M

    2007-01-01

    In this paper, we study the topological entanglement of uniform random polygons in a confined space. We derive the formula for the mean squared linking number of such polygons. For a fixed simple closed curve in the confined space, we rigorously show that the linking probability between this curve and a uniform random polygon of n vertices is at least 1-O(1/√n). Our numerical study also indicates that the linking probability between two uniform random polygons (in a confined space), of m and n vertices respectively, is bounded below by 1-O(1/√(mn)). In particular, the linking probability between two uniform random polygons, both of n vertices, is bounded below by 1-O(1/n)

  13. Local Type Checking for Linked Data Consumers

    Directory of Open Access Journals (Sweden)

    Gabriel Ciobanu

    2013-07-01

    Full Text Available The Web of Linked Data is the cumulation of over a decade of work by the Web standards community in their effort to make data more Web-like. We provide an introduction to the Web of Linked Data from the perspective of a Web developer that would like to build an application using Linked Data. We identify a weakness in the development stack as being a lack of domain specific scripting languages for designing background processes that consume Linked Data. To address this weakness, we design a scripting language with a simple but appropriate type system. In our proposed architecture some data is consumed from sources outside of the control of the system and some data is held locally. Stronger type assumptions can be made about the local data than external data, hence our type system mixes static and dynamic typing. Throughout, we relate our work to the W3C recommendations that drive Linked Data, so our syntax is accessible to Web developers.

  14. Distributed Web-Scale Infrastructure For Crawling, Indexing And Search With Semantic Support

    Directory of Open Access Journals (Sweden)

    Stefan Dlugolinsky

    2012-01-01

    Full Text Available In this paper, we describe our work in progress in the scope of web-scale informationextraction and information retrieval utilizing distributed computing. Wepresent a distributed architecture built on top of the MapReduce paradigm forinformation retrieval, information processing and intelligent search supportedby spatial capabilities. Proposed architecture is focused on crawling documentsin several different formats, information extraction, lightweight semantic annotationof the extracted information, indexing of extracted information andfinally on indexing of documents based on the geo-spatial information foundin a document. We demonstrate the architecture on two use cases, where thefirst is search in job offers retrieved from the LinkedIn portal and the second issearch in BBC news feeds and discuss several problems we had to face duringthe implementation. We also discuss spatial search applications for both casesbecause both LinkedIn job offer pages and BBC news feeds contain a lot of spatialinformation to extract and process.

  15. Building a SuAVE browse interface to R2R's Linked Data

    Science.gov (United States)

    Clark, D.; Stocks, K. I.; Arko, R. A.; Zaslavsky, I.; Whitenack, T.

    2017-12-01

    The Rolling Deck to Repository program (R2R) is creating and evaluating a new browse portal based on the SuAVE platform and the R2R linked data graph. R2R manages the underway sensor data collected by the fleet of US academic research vessels, and provides a discovery and access point to those data at its website, www.rvdata.us. R2R has a database-driven search interface, but seeks a more capable and extensible browse interface that could be built off of the substantial R2R linked data resources. R2R's Linked Data graph organizes its data holdings around key concepts (e.g. cruise, vessel, device type, operator, award, organization, publication), anchored by persistent identifiers where feasible. The "Survey Analysis via Visual Exploration" or SuAVE platform (suave.sdsc.edu) is a system for online publication, sharing, and analysis of images and metadata. It has been implemented as an interface to diverse data collections, but has not been driven off of linked data in the past. SuAVE supports several features of interest to R2R, including faceted searching, collaborative annotations, efficient subsetting, Google maps-like navigation over an image gallery, and several types of data analysis. Our initial SuAVE-based implementation was through a CSV export from the R2R PostGIS-enabled PostgreSQL database. This served to demonstrate the utility of SuAVE but was static and required reloading as R2R data holdings grew. We are now working to implement a SPARQL-based ("RDF Query Language") service that directly leverages the R2R Linked Data graph and offers the ability to subset and/or customize output.We will show examples of SuAVE faceted searches on R2R linked data concepts, and discuss our experience to date with this work in progress.

  16. Simple Identification of Human Taenia Species by Multiplex Loop-Mediated Isothermal Amplification in Combination with Dot Enzyme-Linked Immunosorbent Assay

    Science.gov (United States)

    Nkouawa, Agathe; Sako, Yasuhito; Okamoto, Munehiro; Ito, Akira

    2016-01-01

    For differential detection of Taenia solium, Taenia saginata, and Taenia asiatica, loop-mediated isothermal amplification (LAMP) assay targeting the cytochrome c oxidase subunit 1 gene has been recently developed and shown to be sensitive, specific, and effective. However, to achieve differential identification, one specimen requires three reaction mixtures containing a primer set of each Taenia species separately, which is complex and time consuming and increases the risk of cross-contamination. In this study, we developed a simple differential identification of human Taenia species using multiplex LAMP (mLAMP) in combination with dot enzyme-linked immunosorbent assay (dot-ELISA). Forward inner primers of T. solium, T. saginata, and T. asiatica labeled with fluorescein isothiocyanate (FITC), digoxigenin (DIG), and tetramethylrhodamine (TAMRA), respectively, and biotin-labeled backward inner primers were used in mLAMP. The mLAMP assay succeeded in specific amplification of each respective target gene in a single tube. Furthermore, the mLAMP product from each species was easily distinguished by dot-ELISA with an antibody specific for FITC, DIG, or TAMRA. The mLAMP assay in combination with dot-ELISA will make identification of human Taenia species simpler, easier, and more practical. PMID:27044566

  17. Linking lab and field

    International Nuclear Information System (INIS)

    Cronje, P.B.

    1988-01-01

    The multitude of different supplements recommended for animals grazing natural pastures, which testifies to the need for a metabolic basis for supplementary feeding practices. The first approach to this problem was to simulate different feeding conditions in the laboratory, where the metabolic responses of body tissues to changes in the supply of purified nutrients could be studied using radioisotope techniques. The second step was to link these fundamental studies to field conditions. The results of these studies suggest that the efficiency of feed conversion and growth rates of ruminants grazing winter pastures in the highveld region of South Africa could be substantially improved by strategic supplementation with glucose precursors. Acetate clearance rate represents a valuable link in the process of applying information obtained from controlled laboratory experiments to field conditions. As this technique is inexpensive, quick and simple to carry out, it is ideally suited to application under field conditions where the use of isotopes is impractical. By providing a link with field conditions, it greatly extended the scope and practical application of isotope tracer techniques

  18. Molecule database framework: a framework for creating database applications with chemical structure search capability.

    Science.gov (United States)

    Kiener, Joos

    2013-12-11

    Research in organic chemistry generates samples of novel chemicals together with their properties and other related data. The involved scientists must be able to store this data and search it by chemical structure. There are commercial solutions for common needs like chemical registration systems or electronic lab notebooks. However for specific requirements of in-house databases and processes no such solutions exist. Another issue is that commercial solutions have the risk of vendor lock-in and may require an expensive license of a proprietary relational database management system. To speed up and simplify the development for applications that require chemical structure search capabilities, I have developed Molecule Database Framework. The framework abstracts the storing and searching of chemical structures into method calls. Therefore software developers do not require extensive knowledge about chemistry and the underlying database cartridge. This decreases application development time. Molecule Database Framework is written in Java and I created it by integrating existing free and open-source tools and frameworks. The core functionality includes:•Support for multi-component compounds (mixtures)•Import and export of SD-files•Optional security (authorization)For chemical structure searching Molecule Database Framework leverages the capabilities of the Bingo Cartridge for PostgreSQL and provides type-safe searching, caching, transactions and optional method level security. Molecule Database Framework supports multi-component chemical compounds (mixtures).Furthermore the design of entity classes and the reasoning behind it are explained. By means of a simple web application I describe how the framework could be used. I then benchmarked this example application to create some basic performance expectations for chemical structure searches and import and export of SD-files. By using a simple web application it was shown that Molecule Database Framework

  19. Electronic biomedical literature search for budding researcher.

    Science.gov (United States)

    Thakre, Subhash B; Thakre S, Sushama S; Thakre, Amol D

    2013-09-01

    Search for specific and well defined literature related to subject of interest is the foremost step in research. When we are familiar with topic or subject then we can frame appropriate research question. Appropriate research question is the basis for study objectives and hypothesis. The Internet provides a quick access to an overabundance of the medical literature, in the form of primary, secondary and tertiary literature. It is accessible through journals, databases, dictionaries, textbooks, indexes, and e-journals, thereby allowing access to more varied, individualised, and systematic educational opportunities. Web search engine is a tool designed to search for information on the World Wide Web, which may be in the form of web pages, images, information, and other types of files. Search engines for internet-based search of medical literature include Google, Google scholar, Scirus, Yahoo search engine, etc., and databases include MEDLINE, PubMed, MEDLARS, etc. Several web-libraries (National library Medicine, Cochrane, Web of Science, Medical matrix, Emory libraries) have been developed as meta-sites, providing useful links to health resources globally. A researcher must keep in mind the strengths and limitations of a particular search engine/database while searching for a particular type of data. Knowledge about types of literature, levels of evidence, and detail about features of search engine as available, user interface, ease of access, reputable content, and period of time covered allow their optimal use and maximal utility in the field of medicine. Literature search is a dynamic and interactive process; there is no one way to conduct a search and there are many variables involved. It is suggested that a systematic search of literature that uses available electronic resource effectively, is more likely to produce quality research.

  20. Relay Placement for FSO Multihop DF Systems With Link Obstacles and Infeasible Regions

    KAUST Repository

    Zhu, Bingcheng

    2015-05-19

    Optimal relay placement is studied for free-space optical multihop communication with link obstacles and infeasible regions. An optimal relay placement scheme is proposed to achieve the lowest outage probability, enable the links to bypass obstacles of various geometric shapes, and place the relay nodes in specified available regions. When the number of relay nodes is large, the searching space can grow exponentially, and thus, a grouping optimization technique is proposed to reduce the searching time. We numerically demonstrate that the grouping optimization can provide suboptimal solutions close to the optimal solutions, but the average searching time linearly grows with the number of relay nodes. Two useful theorems are presented to reveal insights into the optimal relay locations. Simulation results show that our proposed optimization framework can effectively provide desirable solution to the problem of optimal relay nodes placement. © 2015 IEEE.

  1. WCSTools 3.0: More Tools for Image Astrometry and Catalog Searching

    Science.gov (United States)

    Mink, Douglas J.

    For five years, WCSTools has provided image astrometry for astronomers who need accurate positions for objects they wish to observe. Other functions have been added and improved since the package was first released. Support has been added for new catalogs, such as the GSC-ACT, 2MASS Point Source Catalog, and GSC II, as they have been published. A simple command line interface can search any supported catalog, returning information in several standard formats, whether the catalog is on a local disk or searchable over the World Wide Web. The catalog searching routine can be located on either end (or both ends!) of such a web connection, and the output from one catalog search can be used as the input to another search.

  2. Usage of LinkedIn in the labour market

    OpenAIRE

    Dušenka, Tomáš

    2017-01-01

    This Master thesis looks into the usage of the social network LinkedIn in the labour market by university students and graduates. In the theory, there is aim at explanation of the relationship between human and work, and also how the recruitment process looks like. In the practical part, there is explained how LinkedIn works and then analyzed the process of using it by university students and graduates when searching for a job. At the end, based on the analysis, there is a suggestion how to u...

  3. Impaired eye region search accuracy in children with autistic spectrum disorders.

    Directory of Open Access Journals (Sweden)

    John R Pruett

    Full Text Available To explore mechanisms underlying reduced fixation of eyes in autism, children with autistic spectrum disorders (ASD and typically developing children were tested in five visual search experiments: simple color feature; color-shape conjunction; face in non-face objects; mouth region; and eye region. No group differences were found for reaction time profile shapes in any of the five experiments, suggesting intact basic search mechanics in children with ASD. Contrary to early reports in the literature, but consistent with other more recent findings, we observed no superiority for conjunction search in children with ASD. Importantly, children with ASD did show reduced accuracy for eye region search (p = .005, suggesting that eyes contribute less to high-level face representations in ASD or that there is an eye region-specific disruption to attentional processes engaged by search in ASD.

  4. Impaired eye region search accuracy in children with autistic spectrum disorders.

    Science.gov (United States)

    Pruett, John R; Hoertel, Sarah; Constantino, John N; Moll, Angela LaMacchia; McVey, Kelly; Squire, Emma; Feczko, Eric; Povinelli, Daniel J; Petersen, Steven E

    2013-01-01

    To explore mechanisms underlying reduced fixation of eyes in autism, children with autistic spectrum disorders (ASD) and typically developing children were tested in five visual search experiments: simple color feature; color-shape conjunction; face in non-face objects; mouth region; and eye region. No group differences were found for reaction time profile shapes in any of the five experiments, suggesting intact basic search mechanics in children with ASD. Contrary to early reports in the literature, but consistent with other more recent findings, we observed no superiority for conjunction search in children with ASD. Importantly, children with ASD did show reduced accuracy for eye region search (p = .005), suggesting that eyes contribute less to high-level face representations in ASD or that there is an eye region-specific disruption to attentional processes engaged by search in ASD.

  5. Port-based modeling of a flexible link

    NARCIS (Netherlands)

    Macchelli, A.; Macchelli, A.; Hirohika, A.; Lynch, K.; Melchiorri, C.; Park, F.C.; Stramigioli, Stefano; Parker, L.E.

    In this paper, a simple way to model flexible robotic links is presented. This is different from classical approaches and from the Euler–Bernoulli or Timoshenko theory, in that the proposed model is able to describe large deflections in 3-D space and does not rely on any finite-dimensional

  6. Millennial Students’ Online Search Strategies are Associated With Their Mental Models of Search. A Review of: Holman, L. (2011. Millennial students’ mental models of search: Implications for academic librarians and database developers. Journal of Academic Librarianship, 37(1, 19-27. doi:10.1016/j.acalib.2010.10.003

    Directory of Open Access Journals (Sweden)

    Leslie Bussert

    2011-09-01

    Full Text Available Objective – To examine first-year college students’ information seeking behaviours and determine whether their mental models of the search process influence their ability to effectively search for and find scholarly materials.Design – Mixed methods including contextual inquiry, concept mapping, observation, and interviews.Setting – University of Baltimore, a public institution in Maryland, United States of America, offering undergraduate, graduate, and professional degrees.Subjects – A total of 21 first-year undergraduate students, ages 16 to 19 years, undertaking research assignments for which they chose to use online resources.Methods – First-year students were recruited in the fall of 2008 and met with the researcher in a university usability lab for about one hour over a three week period. The researcher observed and videotaped the students as they conducted research in their chosen search engines or article databases. The searches were captured using software, and students were encouraged to think aloud about their research process, search strategies, and anticipated search results. Observation sessions concluded with a 10-question interview incorporating a review of the keywords the student used, the student’s reflection on the success of his or her searches, and possible alternate keywords. The interview also offered prompts to help the researcher learn about students’ conceptualizations of search tools’ utilization of keywords to generate results. The researcher then asked the students to provide a visual diagram of the relationship between their search terms and the items retrieved in the search tool.Data were analyzed by identifying the 21 different search tools used by the students and categorizing all 210 searches and student diagrams for further analysis. A scheme similar to Guinee, Eagleton, and Hall’s (2003 characterized the student searches into four categories: simple single-term searches, topic plus focus

  7. Top partners searches and composite Higgs models

    International Nuclear Information System (INIS)

    Matsedonskyi, Oleksii; Panico, Giuliano; Wulzer, Andrea

    2016-01-01

    Colored fermionic partners of the top quark are well-known signatures of the Composite Higgs scenario and for this reason they have been and will be subject of an intensive experimental study at the LHC. Performing an assessment of the theoretical implications of this experimental effort is the goal of the present paper. We proceed by analyzing a set of simple benchmark models, characterized by simple two-dimensional parameter spaces where the results of the searches are conveniently visualized and their impact quantified. We only draw exclusion contours, in the hypothesis of no signal, but of course our formalism could equally well be used to report discoveries in a theoretically useful format.

  8. Search Analytics: Automated Learning, Analysis, and Search with Open Source

    Science.gov (United States)

    Hundman, K.; Mattmann, C. A.; Hyon, J.; Ramirez, P.

    2016-12-01

    The sheer volume of unstructured scientific data makes comprehensive human analysis impossible, resulting in missed opportunities to identify relationships, trends, gaps, and outliers. As the open source community continues to grow, tools like Apache Tika, Apache Solr, Stanford's DeepDive, and Data-Driven Documents (D3) can help address this challenge. With a focus on journal publications and conference abstracts often in the form of PDF and Microsoft Office documents, we've initiated an exploratory NASA Advanced Concepts project aiming to use the aforementioned open source text analytics tools to build a data-driven justification for the HyspIRI Decadal Survey mission. We call this capability Search Analytics, and it fuses and augments these open source tools to enable the automatic discovery and extraction of salient information. In the case of HyspIRI, a hyperspectral infrared imager mission, key findings resulted from the extractions and visualizations of relationships from thousands of unstructured scientific documents. The relationships include links between satellites (e.g. Landsat 8), domain-specific measurements (e.g. spectral coverage) and subjects (e.g. invasive species). Using the above open source tools, Search Analytics mined and characterized a corpus of information that would be infeasible for a human to process. More broadly, Search Analytics offers insights into various scientific and commercial applications enabled through missions and instrumentation with specific technical capabilities. For example, the following phrases were extracted in close proximity within a publication: "In this study, hyperspectral images…with high spatial resolution (1 m) were analyzed to detect cutleaf teasel in two areas. …Classification of cutleaf teasel reached a users accuracy of 82 to 84%." Without reading a single paper we can use Search Analytics to automatically identify that a 1 m spatial resolution provides a cutleaf teasel detection users accuracy of 82

  9. Search efficiency of biased migration towards stationary or moving targets in heterogeneously structured environments

    Science.gov (United States)

    Azimzade, Youness; Mashaghi, Alireza

    2017-12-01

    Efficient search acts as a strong selective force in biological systems ranging from cellular populations to predator-prey systems. The search processes commonly involve finding a stationary or mobile target within a heterogeneously structured environment where obstacles limit migration. An open generic question is whether random or directionally biased motions or a combination of both provide an optimal search efficiency and how that depends on the motility and density of targets and obstacles. To address this question, we develop a simple model that involves a random walker searching for its targets in a heterogeneous medium of bond percolation square lattice and used mean first passage time (〈T 〉 ) as an indication of average search time. Our analysis reveals a dual effect of directional bias on the minimum value of 〈T 〉 . For a homogeneous medium, directionality always decreases 〈T 〉 and a pure directional migration (a ballistic motion) serves as the optimized strategy, while for a heterogeneous environment, we find that the optimized strategy involves a combination of directed and random migrations. The relative contribution of these modes is determined by the density of obstacles and motility of targets. Existence of randomness and motility of targets add to the efficiency of search. Our study reveals generic and simple rules that govern search efficiency. Our findings might find application in a number of areas including immunology, cell biology, ecology, and robotics.

  10. Linking of uniform random polygons in confined spaces

    Science.gov (United States)

    Arsuaga, J.; Blackstone, T.; Diao, Y.; Karadayi, E.; Saito, M.

    2007-03-01

    In this paper, we study the topological entanglement of uniform random polygons in a confined space. We derive the formula for the mean squared linking number of such polygons. For a fixed simple closed curve in the confined space, we rigorously show that the linking probability between this curve and a uniform random polygon of n vertices is at least 1-O\\big(\\frac{1}{\\sqrt{n}}\\big) . Our numerical study also indicates that the linking probability between two uniform random polygons (in a confined space), of m and n vertices respectively, is bounded below by 1-O\\big(\\frac{1}{\\sqrt{mn}}\\big) . In particular, the linking probability between two uniform random polygons, both of n vertices, is bounded below by 1-O\\big(\\frac{1}{n}\\big) .

  11. Using SQL Databases for Sequence Similarity Searching and Analysis.

    Science.gov (United States)

    Pearson, William R; Mackey, Aaron J

    2017-09-13

    Relational databases can integrate diverse types of information and manage large sets of similarity search results, greatly simplifying genome-scale analyses. By focusing on taxonomic subsets of sequences, relational databases can reduce the size and redundancy of sequence libraries and improve the statistical significance of homologs. In addition, by loading similarity search results into a relational database, it becomes possible to explore and summarize the relationships between all of the proteins in an organism and those in other biological kingdoms. This unit describes how to use relational databases to improve the efficiency of sequence similarity searching and demonstrates various large-scale genomic analyses of homology-related data. It also describes the installation and use of a simple protein sequence database, seqdb_demo, which is used as a basis for the other protocols. The unit also introduces search_demo, a database that stores sequence similarity search results. The search_demo database is then used to explore the evolutionary relationships between E. coli proteins and proteins in other organisms in a large-scale comparative genomic analysis. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  12. Searching for highly entangled multi-qubit states

    International Nuclear Information System (INIS)

    Brown, Iain D K; Stepney, Susan; Sudbery, Anthony; Braunstein, Samuel L

    2005-01-01

    We present a simple numerical optimization procedure to search for highly entangled states of 2, 3, 4 and 5 qubits. We develop a computationally tractable entanglement measure based on the negative partial transpose criterion, which can be applied to quantum systems of an arbitrary number of qubits. The search algorithm attempts to optimize this entanglement cost function to find the maximal entanglement in a quantum system. We present highly entangled 4-qubit and 5-qubit states discovered by this search. We show that the 4-qubit state is not quite as entangled, according to two separate measures, as the conjectured maximally entangled Higuchi-Sudbery state. Using this measure, these states are more highly entangled than the 4-qubit and 5-qubit GHZ states. We also present a conjecture about the NPT measure, inspired by some of our numerical results, that the single-qubit reduced states of maximally entangled states are all totally mixed

  13. Simple heuristics and rules of thumb: where psychologists and behavioural biologists might meet.

    Science.gov (United States)

    Hutchinson, John M C; Gigerenzer, Gerd

    2005-05-31

    The Centre for Adaptive Behaviour and Cognition (ABC) has hypothesised that much human decision-making can be described by simple algorithmic process models (heuristics). This paper explains this approach and relates it to research in biology on rules of thumb, which we also review. As an example of a simple heuristic, consider the lexicographic strategy of Take The Best for choosing between two alternatives: cues are searched in turn until one discriminates, then search stops and all other cues are ignored. Heuristics consist of building blocks, and building blocks exploit evolved or learned abilities such as recognition memory; it is the complexity of these abilities that allows the heuristics to be simple. Simple heuristics have an advantage in making decisions fast and with little information, and in avoiding overfitting. Furthermore, humans are observed to use simple heuristics. Simulations show that the statistical structures of different environments affect which heuristics perform better, a relationship referred to as ecological rationality. We contrast ecological rationality with the stronger claim of adaptation. Rules of thumb from biology provide clearer examples of adaptation because animals can be studied in the environments in which they evolved. The range of examples is also much more diverse. To investigate them, biologists have sometimes used similar simulation techniques to ABC, but many examples depend on empirically driven approaches. ABC's theoretical framework can be useful in connecting some of these examples, particularly the scattered literature on how information from different cues is integrated. Optimality modelling is usually used to explain less detailed aspects of behaviour but might more often be redirected to investigate rules of thumb.

  14. SA-Search: a web tool for protein structure mining based on a Structural Alphabet.

    Science.gov (United States)

    Guyon, Frédéric; Camproux, Anne-Claude; Hochez, Joëlle; Tufféry, Pierre

    2004-07-01

    SA-Search is a web tool that can be used to mine for protein structures and extract structural similarities. It is based on a hidden Markov model derived Structural Alphabet (SA) that allows the compression of three-dimensional (3D) protein conformations into a one-dimensional (1D) representation using a limited number of prototype conformations. Using such a representation, classical methods developed for amino acid sequences can be employed. Currently, SA-Search permits the performance of fast 3D similarity searches such as the extraction of exact words using a suffix tree approach, and the search for fuzzy words viewed as a simple 1D sequence alignment problem. SA-Search is available at http://bioserv.rpbs.jussieu.fr/cgi-bin/SA-Search.

  15. A generalized theory of preferential linking

    Science.gov (United States)

    Hu, Haibo; Guo, Jinli; Liu, Xuan; Wang, Xiaofan

    2014-12-01

    There are diverse mechanisms driving the evolution of social networks. A key open question dealing with understanding their evolution is: How do various preferential linking mechanisms produce networks with different features? In this paper we first empirically study preferential linking phenomena in an evolving online social network, find and validate the linear preference. We propose an analyzable model which captures the real growth process of the network and reveals the underlying mechanism dominating its evolution. Furthermore based on preferential linking we propose a generalized model reproducing the evolution of online social networks, and present unified analytical results describing network characteristics for 27 preference scenarios. We study the mathematical structure of degree distributions and find that within the framework of preferential linking analytical degree distributions can only be the combinations of finite kinds of functions which are related to rational, logarithmic and inverse tangent functions, and extremely complex network structure will emerge even for very simple sublinear preferential linking. This work not only provides a verifiable origin for the emergence of various network characteristics in social networks, but bridges the micro individuals' behaviors and the global organization of social networks.

  16. Evidence for unlimited capacity processing of simple features in visual cortex.

    Science.gov (United States)

    White, Alex L; Runeson, Erik; Palmer, John; Ernst, Zachary R; Boynton, Geoffrey M

    2017-06-01

    Performance in many visual tasks is impaired when observers attempt to divide spatial attention across multiple visual field locations. Correspondingly, neuronal response magnitudes in visual cortex are often reduced during divided compared with focused spatial attention. This suggests that early visual cortex is the site of capacity limits, where finite processing resources must be divided among attended stimuli. However, behavioral research demonstrates that not all visual tasks suffer such capacity limits: The costs of divided attention are minimal when the task and stimulus are simple, such as when searching for a target defined by orientation or contrast. To date, however, every neuroimaging study of divided attention has used more complex tasks and found large reductions in response magnitude. We bridged that gap by using functional magnetic resonance imaging to measure responses in the human visual cortex during simple feature detection. The first experiment used a visual search task: Observers detected a low-contrast Gabor patch within one or four potentially relevant locations. The second experiment used a dual-task design, in which observers made independent judgments of Gabor presence in patches of dynamic noise at two locations. In both experiments, blood-oxygen level-dependent (BOLD) signals in the retinotopic cortex were significantly lower for ignored than attended stimuli. However, when observers divided attention between multiple stimuli, BOLD signals were not reliably reduced and behavioral performance was unimpaired. These results suggest that processing of simple features in early visual cortex has unlimited capacity.

  17. Simple method for evaluating Goldstone diagrams in an angular momentum coupled representation

    International Nuclear Information System (INIS)

    Kuo, T.T.S.; Shurpin, J.; Tam, K.C.; Osnes, E.; Ellis, P.J.

    1981-01-01

    A simple and convenient method is derived for evaluating linked Goldstone diagrams in an angular momentum coupled representation. Our method is general, and can be used to evaluate any effective interaction and/or effective operator diagrams for both closed-shell nuclei (vacuum to vacuum linked diagrams) and open-shell nuclei (valence linked diagrams). The techniques of decomposing diagrams into ladder diagrams, cutting open internal lines and cutting off one-body insertions are introduced. These enable us to determine angular momentum factors associated with diagrams in the coupled representation directly, without the need for carrying out complicated angular momentum algebra. A summary of diagram rules is given

  18. Adding Search as a first-class citizen to Hadoop

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    Apache Hadoop is enabling organizations to collect larger, more varied data - but after it's collected how will it be found? Your users expect to be able to search for information using simple text based queries -- regardless of data location, size, and complexity. How do they quickly find information that's just been created, or been stored for months or even years? Cloudera Search Senior Software Engineer Wolfgang Hoschek will present a solution to this problem; what architecture is necessary to search HDFS and HBase? How was Apache Solr, Lucene, Flume and MapReduce integrated to allow for Near Real Time and Batch indexing of data? What are the solved problems and what's still to come? Join us for an exciting discussion on this new technology. About the speaker Wolfgang Hoschek is a Software Engineer at Cloudera working on the Hadoop Platform and Cloudera Search team. He is a committer on the Apache Flume and Apache Lucene/Solr projects, a committer on the Kite project, a committer...

  19. Search Engine Optimization

    CERN Document Server

    Davis, Harold

    2006-01-01

    SEO--short for Search Engine Optimization--is the art, craft, and science of driving web traffic to web sites. Web traffic is food, drink, and oxygen--in short, life itself--to any web-based business. Whether your web site depends on broad, general traffic, or high-quality, targeted traffic, this PDF has the tools and information you need to draw more traffic to your site. You'll learn how to effectively use PageRank (and Google itself); how to get listed, get links, and get syndicated; and much more. The field of SEO is expanding into all the possible ways of promoting web traffic. This

  20. A Step Beyond Simple Keyword Searches: Services Enabled by a Full Content Digital Journal Archive

    Science.gov (United States)

    Boccippio, Dennis J.

    2003-01-01

    The problems of managing and searching large archives of scientific journal articles can potentially be addressed through data mining and statistical techniques matured primarily for quantitative scientific data analysis. A journal paper could be represented by a multivariate descriptor, e.g., the occurrence counts of a number key technical terms or phrases (keywords), perhaps derived from a controlled vocabulary ( e . g . , the American Meteorological Society's Glossary of Meteorology) or bootstrapped from the journal archive itself. With this technique, conventional statistical classification tools can be leveraged to address challenges faced by both scientists and professional societies in knowledge management. For example, cluster analyses can be used to find bundles of "most-related" papers, and address the issue of journal bifurcation (when is a new journal necessary, and what topics should it encompass). Similarly, neural networks can be trained to predict the optimal journal (within a society's collection) in which a newly submitted paper should be published. Comparable techniques could enable very powerful end-user tools for journal searches, all premised on the view of a paper as a data point in a multidimensional descriptor space, e.g.: "find papers most similar to the one I am reading", "build a personalized subscription service, based on the content of the papers I am interested in, rather than preselected keywords", "find suitable reviewers, based on the content of their own published works", etc. Such services may represent the next "quantum leap" beyond the rudimentary search interfaces currently provided to end-users, as well as a compelling value-added component needed to bridge the print-to-digital-medium gap, and help stabilize professional societies' revenue stream during the print-to-digital transition.

  1. Searches for very rare decays of kaons

    International Nuclear Information System (INIS)

    Lang, K.

    1997-01-01

    The physics motivation for searches for very rare kaon decays, either forbidden or suppressed within the Standard Model, is briefly discussed. Simple arguments conclude that such searches probe possible new forces at a 200 TeV mass scale or constitute a precision test of the electroweak model. The examples of such process are decays of K L 0 → μ ± e -+ , K + → π + μ + e - , K L 0 → μ + μ - , and K + → π → π + ν bar ν. We present the current experimental status and describe the new efforts to reach sensitivities down to one part in 10 12 . The discussion is focused on the experimental program at the Alternating Gradient Synchrotron at Brookhaven National Laboratory, where intense beams make such studies possible

  2. Searches for very rare decays of kaons

    International Nuclear Information System (INIS)

    Lang, K.

    1995-01-01

    The physics motivation for searches for very rare kaon decays, either forbidden or suppressed within the Standard Model, is briefly discussed. Simple arguments conclude that such searches probe possible new forces at a 200 TeV mass scale or constitute a precision test of the electroweak model. The examples of such processes are decays of K L O →μ ± e minus-plus , K + →π + μ + e - , K L O →μ - , and K + →π + ν bar ν. We present the current experimental status and describe the new efforts to reach sensitivities down to 1 part in 10 12 . The discussion is focused on the experimental program at the Alternating Gradient Synchrotron at Brookhaven National Laboratory, where intense beams make such studies possible

  3. A simple, specific high-throughput enzyme-linked immunosorbent assay (ELISA) for quantitative determination of melatonin in cell culture medium.

    Science.gov (United States)

    Li, Ye; Cassone, Vincent M

    2015-09-01

    A simple, specific, high-throughput enzyme-linked immunosorbent assay (ELISA) for quantitative determination of melatonin was developed for directly measuring melatonin in cell culture medium with 10% FBS. This assay adopts a commercial monoclonal melatonin antibody and melatonin-HRP conjugate, so it can be applied in multiple labs rapidly with low cost compared with commercial RIA and ELISA kits. In addition, the procedure is much simpler with only four steps: 1) sample/conjugate incubation, 2) plate washing, 3) TMB color reaction and 4) reading of results. The standards of the assay cover a wide working range from 100 pg/mL to 10 ng/mL. The sensitivity was 68 pg/mL in cell culture medium with 10% FBS and 26 pg/mL in PBS with as little as 25 μL sample volume. The recovery of melatonin from cell culture medium was 101.0%. The principal cross-reacting compound was 5-methoxytryptophol (0.1%). The variation coefficients of the assay, within and between runs, ranged between 6.68% and 15.76% in cell culture medium. The mean linearity of a series diluted cell culture medium sample was 105% (CV=5%), ranging between 98% and 111%, y=5.5263x+0.0646, R(2)=0.99. The assay enables small research and teaching labs to reliably measure this important neurohormone. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Using Internet Search Engines to Obtain Medical Information: A Comparative Study

    Science.gov (United States)

    Wang, Liupu; Wang, Juexin; Wang, Michael; Li, Yong; Liang, Yanchun

    2012-01-01

    Background The Internet has become one of the most important means to obtain health and medical information. It is often the first step in checking for basic information about a disease and its treatment. The search results are often useful to general users. Various search engines such as Google, Yahoo!, Bing, and Ask.com can play an important role in obtaining medical information for both medical professionals and lay people. However, the usability and effectiveness of various search engines for medical information have not been comprehensively compared and evaluated. Objective To compare major Internet search engines in their usability of obtaining medical and health information. Methods We applied usability testing as a software engineering technique and a standard industry practice to compare the four major search engines (Google, Yahoo!, Bing, and Ask.com) in obtaining health and medical information. For this purpose, we searched the keyword breast cancer in Google, Yahoo!, Bing, and Ask.com and saved the results of the top 200 links from each search engine. We combined nonredundant links from the four search engines and gave them to volunteer users in an alphabetical order. The volunteer users evaluated the websites and scored each website from 0 to 10 (lowest to highest) based on the usefulness of the content relevant to breast cancer. A medical expert identified six well-known websites related to breast cancer in advance as standards. We also used five keywords associated with breast cancer defined in the latest release of Systematized Nomenclature of Medicine-Clinical Terms (SNOMED CT) and analyzed their occurrence in the websites. Results Each search engine provided rich information related to breast cancer in the search results. All six standard websites were among the top 30 in search results of all four search engines. Google had the best search validity (in terms of whether a website could be opened), followed by Bing, Ask.com, and Yahoo!. The search

  5. Using Internet search engines to obtain medical information: a comparative study.

    Science.gov (United States)

    Wang, Liupu; Wang, Juexin; Wang, Michael; Li, Yong; Liang, Yanchun; Xu, Dong

    2012-05-16

    The Internet has become one of the most important means to obtain health and medical information. It is often the first step in checking for basic information about a disease and its treatment. The search results are often useful to general users. Various search engines such as Google, Yahoo!, Bing, and Ask.com can play an important role in obtaining medical information for both medical professionals and lay people. However, the usability and effectiveness of various search engines for medical information have not been comprehensively compared and evaluated. To compare major Internet search engines in their usability of obtaining medical and health information. We applied usability testing as a software engineering technique and a standard industry practice to compare the four major search engines (Google, Yahoo!, Bing, and Ask.com) in obtaining health and medical information. For this purpose, we searched the keyword breast cancer in Google, Yahoo!, Bing, and Ask.com and saved the results of the top 200 links from each search engine. We combined nonredundant links from the four search engines and gave them to volunteer users in an alphabetical order. The volunteer users evaluated the websites and scored each website from 0 to 10 (lowest to highest) based on the usefulness of the content relevant to breast cancer. A medical expert identified six well-known websites related to breast cancer in advance as standards. We also used five keywords associated with breast cancer defined in the latest release of Systematized Nomenclature of Medicine-Clinical Terms (SNOMED CT) and analyzed their occurrence in the websites. Each search engine provided rich information related to breast cancer in the search results. All six standard websites were among the top 30 in search results of all four search engines. Google had the best search validity (in terms of whether a website could be opened), followed by Bing, Ask.com, and Yahoo!. The search results highly overlapped between the

  6. Optimizing Linear Functions with Randomized Search Heuristics - The Robustness of Mutation

    DEFF Research Database (Denmark)

    Witt, Carsten

    2012-01-01

    The analysis of randomized search heuristics on classes of functions is fundamental for the understanding of the underlying stochastic process and the development of suitable proof techniques. Recently, remarkable progress has been made in bounding the expected optimization time of the simple (1...

  7. The Complex Dynamics of Sponsored Search Markets

    Science.gov (United States)

    Robu, Valentin; La Poutré, Han; Bohte, Sander

    This paper provides a comprehensive study of the structure and dynamics of online advertising markets, mostly based on techniques from the emergent discipline of complex systems analysis. First, we look at how the display rank of a URL link influences its click frequency, for both sponsored search and organic search. Second, we study the market structure that emerges from these queries, especially the market share distribution of different advertisers. We show that the sponsored search market is highly concentrated, with less than 5% of all advertisers receiving over 2/3 of the clicks in the market. Furthermore, we show that both the number of ad impressions and the number of clicks follow power law distributions of approximately the same coefficient. However, we find this result does not hold when studying the same distribution of clicks per rank position, which shows considerable variance, most likely due to the way advertisers divide their budget on different keywords. Finally, we turn our attention to how such sponsored search data could be used to provide decision support tools for bidding for combinations of keywords. We provide a method to visualize keywords of interest in graphical form, as well as a method to partition these graphs to obtain desirable subsets of search terms.

  8. X-ray-mediated cross linking of protein and DNA

    International Nuclear Information System (INIS)

    Minsky, B.D.; Braun, A.

    1977-01-01

    Using a simple filter assay for the binding of BSA or lysozyme to DNA, two mechanisms of x-ray-mediated cross linking are shown to occur. One, a fast reaction, appears to involve a radical intermediate, is inhibited by high pH and salt, and seems to be enhanced by deoxygenation. The second mechanism, a slow time-dependent component, differs from the fast reaction in its stimulation by histidine, its inhibition by catalase, and the lack of an oxygen effect. Separate irradiation of DNA or water does not lead to cross linking. However, separate irradiation of protein leads to cross linking which proceeds with slow-component kinetics

  9. Searching for suicide-related information on Chinese websites.

    Science.gov (United States)

    Chen, Ying-Yeh; Hung, Galen Chin-Lun; Cheng, Qijin; Tsai, Chi-Wei; Wu, Kevin Chien-Chang

    2017-12-01

    Growing concerns about cyber-suicide have prompted many studies on suicide information available on the web. However, very few studies have considered non-English websites. We aimed to analyze online suicide-related information accessed through Chinese-language websites. We used Taiwan's two most popular search engines (Google and Yahoo) to explore the results returned from six suicide-related search terms in March 2016. The first three pages listing the results from each search were analyzed and rated based on the attitude towards suicide (pro-suicide, anti-suicide, neutral/mixed, not a suicide site, or error). Comparisons across different search terms were also performed. In all, 375 linked webpages were included; 16.3% of the webpages were pro-suicide and 41.3% were anti-suicide. The majority of the pro-suicide sites were user-generated webpages (96.7%). Searches using the keywords 'ways to kill yourself' (31.7%) and 'painless suicide' (28.3%) generated much larger numbers of harmful webpages than the term 'suicide' (4.3%). We conclude that collaborative efforts with internet service providers and search engines to improve the ranking of anti-suicide webpages and websites and implement online suicide reporting guidelines are highly encouraged. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Variability of patient spine education by Internet search engine.

    Science.gov (United States)

    Ghobrial, George M; Mehdi, Angud; Maltenfort, Mitchell; Sharan, Ashwini D; Harrop, James S

    2014-03-01

    Patients are increasingly reliant upon the Internet as a primary source of medical information. The educational experience varies by search engine, search term, and changes daily. There are no tools for critical evaluation of spinal surgery websites. To highlight the variability between common search engines for the same search terms. To detect bias, by prevalence of specific kinds of websites for certain spinal disorders. Demonstrate a simple scoring system of spinal disorder website for patient use, to maximize the quality of information exposed to the patient. Ten common search terms were used to query three of the most common search engines. The top fifty results of each query were tabulated. A negative binomial regression was performed to highlight the variation across each search engine. Google was more likely than Bing and Yahoo search engines to return hospital ads (P=0.002) and more likely to return scholarly sites of peer-reviewed lite (P=0.003). Educational web sites, surgical group sites, and online web communities had a significantly higher likelihood of returning on any search, regardless of search engine, or search string (P=0.007). Likewise, professional websites, including hospital run, industry sponsored, legal, and peer-reviewed web pages were less likely to be found on a search overall, regardless of engine and search string (P=0.078). The Internet is a rapidly growing body of medical information which can serve as a useful tool for patient education. High quality information is readily available, provided that the patient uses a consistent, focused metric for evaluating online spine surgery information, as there is a clear variability in the way search engines present information to the patient. Published by Elsevier B.V.

  11. Fermionic dark matter in a simple t-channel model

    International Nuclear Information System (INIS)

    Goyal, Ashok; Kumar, Mukesh

    2016-01-01

    We consider a fermionic dark matter (DM) particle in renormalizable Standard Model (SM) gauge interactions in a simple t-channel model. The DM particle interactions with SM fermions is through the exchange of scalar and vector mediators which carry colour or lepton number. In the case of coloured mediators considered in this study, we find that if the DM is thermally produced and accounts for the observed relic density almost the entire parameter space is ruled out by the direct detection observations. The bounds from the monojet plus missing energy searches at the Large Hadron Collider are less stringent in this case. In contrast for the case of Majorana DM, we obtain strong bounds from the monojet searches which rule out DM particles of mass less than about a few hundred GeV for both the scalar and vector mediators.

  12. Simple Identification of Human Taenia Species by Multiplex Loop-Mediated Isothermal Amplification in Combination with Dot Enzyme-Linked Immunosorbent Assay.

    Science.gov (United States)

    Nkouawa, Agathe; Sako, Yasuhito; Okamoto, Munehiro; Ito, Akira

    2016-06-01

    For differential detection of Taenia solium, Taenia saginata, and Taenia asiatica, loop-mediated isothermal amplification (LAMP) assay targeting the cytochrome c oxidase subunit 1 gene has been recently developed and shown to be sensitive, specific, and effective. However, to achieve differential identification, one specimen requires three reaction mixtures containing a primer set of each Taenia species separately, which is complex and time consuming and increases the risk of cross-contamination. In this study, we developed a simple differential identification of human Taenia species using multiplex LAMP (mLAMP) in combination with dot enzyme-linked immunosorbent assay (dot-ELISA). Forward inner primers of T. solium, T. saginata, and T. asiatica labeled with fluorescein isothiocyanate (FITC), digoxigenin (DIG), and tetramethylrhodamine (TAMRA), respectively, and biotin-labeled backward inner primers were used in mLAMP. The mLAMP assay succeeded in specific amplification of each respective target gene in a single tube. Furthermore, the mLAMP product from each species was easily distinguished by dot-ELISA with an antibody specific for FITC, DIG, or TAMRA. The mLAMP assay in combination with dot-ELISA will make identification of human Taenia species simpler, easier, and more practical. © The American Society of Tropical Medicine and Hygiene.

  13. An improved harmony search algorithm for power economic load dispatch

    Energy Technology Data Exchange (ETDEWEB)

    Santos Coelho, Leandro dos [Pontifical Catholic University of Parana, PUCPR, Industrial and Systems Engineering Graduate Program, PPGEPS, Imaculada Conceicao, 1155, 80215-901 Curitiba, PR (Brazil)], E-mail: leandro.coelho@pucpr.br; Mariani, Viviana Cocco [Pontifical Catholic University of Parana, PUCPR, Department of Mechanical Engineering, PPGEM, Imaculada Conceicao, 1155, 80215-901 Curitiba, PR (Brazil)], E-mail: viviana.mariani@pucpr.br

    2009-10-15

    A meta-heuristic algorithm called harmony search (HS), mimicking the improvisation process of music players, has been recently developed. The HS algorithm has been successful in several optimization problems. The HS algorithm does not require derivative information and uses stochastic random search instead of a gradient search. In addition, the HS algorithm is simple in concept, few in parameters, and easy in implementation. This paper presents an improved harmony search (IHS) algorithm based on exponential distribution for solving economic dispatch problems. A 13-unit test system with incremental fuel cost function taking into account the valve-point loading effects is used to illustrate the effectiveness of the proposed IHS method. Numerical results show that the IHS method has good convergence property. Furthermore, the generation costs of the IHS method are lower than those of the classical HS and other optimization algorithms reported in recent literature.

  14. An improved harmony search algorithm for power economic load dispatch

    Energy Technology Data Exchange (ETDEWEB)

    Coelho, Leandro dos Santos [Pontifical Catholic Univ. of Parana, PUCPR, Industrial and Systems Engineering Graduate Program, PPGEPS, Imaculada Conceicao, 1155, 80215-901 Curitiba, PR (Brazil); Mariani, Viviana Cocco [Pontifical Catholic Univ. of Parana, PUCPR, Dept. of Mechanical Engineering, PPGEM, Imaculada Conceicao, 1155, 80215-901 Curitiba, PR (Brazil)

    2009-10-15

    A meta-heuristic algorithm called harmony search (HS), mimicking the improvisation process of music players, has been recently developed. The HS algorithm has been successful in several optimization problems. The HS algorithm does not require derivative information and uses stochastic random search instead of a gradient search. In addition, the HS algorithm is simple in concept, few in parameters, and easy in implementation. This paper presents an improved harmony search (IHS) algorithm based on exponential distribution for solving economic dispatch problems. A 13-unit test system with incremental fuel cost function taking into account the valve-point loading effects is used to illustrate the effectiveness of the proposed IHS method. Numerical results show that the IHS method has good convergence property. Furthermore, the generation costs of the IHS method are lower than those of the classical HS and other optimization algorithms reported in recent literature. (author)

  15. An improved harmony search algorithm for power economic load dispatch

    International Nuclear Information System (INIS)

    Santos Coelho, Leandro dos; Mariani, Viviana Cocco

    2009-01-01

    A meta-heuristic algorithm called harmony search (HS), mimicking the improvisation process of music players, has been recently developed. The HS algorithm has been successful in several optimization problems. The HS algorithm does not require derivative information and uses stochastic random search instead of a gradient search. In addition, the HS algorithm is simple in concept, few in parameters, and easy in implementation. This paper presents an improved harmony search (IHS) algorithm based on exponential distribution for solving economic dispatch problems. A 13-unit test system with incremental fuel cost function taking into account the valve-point loading effects is used to illustrate the effectiveness of the proposed IHS method. Numerical results show that the IHS method has good convergence property. Furthermore, the generation costs of the IHS method are lower than those of the classical HS and other optimization algorithms reported in recent literature.

  16. Combining of Direct Search and Signal-to-Noise Ratio for economic dispatch optimization

    International Nuclear Information System (INIS)

    Lin, Whei-Min; Gow, Hong-Jey; Tsai, Ming-Tang

    2011-01-01

    This paper integrated the ideas of Direct Search and Signal-to-Noise Ratio (SNR) to develop a Novel Direct Search (NDS) method for solving the non-convex economic dispatch problems. NDS consists of three stages: Direct Search (DS), Global SNR (GSNR) and Marginal Compensation (MC) stages. DS provides a basic solution. GSNR searches the point with optimization strategy. MC fulfills the power balance requirement. With NDS, the infinite solution space becomes finite. Furthermore, a same optimum solution can be repeatedly reached. Effectiveness of NDS is demonstrated with three examples and the solutions were compared with previously published results. Test results show that the proposed method is simple, robust, and more effective than many other previously developed algorithms.

  17. A simple method for labelling proteins with 211At via diazotized aromatic diamine

    International Nuclear Information System (INIS)

    Wunderlich, G.; Franke, W.-G.; Fischer, S.; Dreyer, R.

    1987-01-01

    A simple and rapid method for labelling proteins with 211 At by means of a 1,4-diaminobenzene link is described. This link is transformed into the diazonium salt and subsequently reactions of both 211 At and proteins with the diazonium salt take place simultaneously. For possibly high yields of astatized protein an appropriate temperature of 273 K was found. The results demonstrate the difference between the reaction mechanisms of iodine and astatine with proteins. (author)

  18. The Simple Analytics of the Environmental Kuznets Curve

    OpenAIRE

    James Andreoni; Arik Levinson

    1998-01-01

    Evidence suggests that some pollutants follow an inverse-U-shaped pattern relative to countries' incomes. This relationship has been called the out a simple and straight-forward static model of the microfoundations of the pollution-income relationship. We show that the environmental Kuznets curve can be derived directly from the technological link between consumption of a desired good and abatement of its undesirable byproduct. The inverse-U shape does not depend on the dynamics of growth, po...

  19. The internet and intelligent machines: search engines, agents and robots

    International Nuclear Information System (INIS)

    Achenbach, S.; Alfke, H.

    2000-01-01

    The internet plays an important role in a growing number of medical applications. Finding relevant information is not always easy as the amount of available information on the Web is rising quickly. Even the best Search Engines can only collect links to a fraction of all existing Web pages. In addition, many of these indexed documents have been changed or deleted. The vast majority of information on the Web is not searchable with conventional methods. New search strategies, technologies and standards are combined in Intelligent Search Agents (ISA) an Robots, which can retrieve desired information in a specific approach. Conclusion: The article describes differences between ISAs and conventional Search Engines and how communication between Agents improves their ability to find information. Examples of existing ISAs are given and the possible influences on the current and future work in radiology is discussed. (orig.) [de

  20. Searching Online Chemical Data Repositories via the ChemAgora Portal.

    Science.gov (United States)

    Zanzi, Antonella; Wittwehr, Clemens

    2017-12-26

    ChemAgora, a web application designed and developed in the context of the "Data Infrastructure for Chemical Safety Assessment" (diXa) project, provides search capabilities to chemical data from resources available online, enabling users to cross-reference their search results with both regulatory chemical information and public chemical databases. ChemAgora, through an on-the-fly search, informs whether a chemical is known or not in each of the external data sources and provides clikable links leading to the third-party web site pages containing the information. The original purpose of the ChemAgora application was to correlate studies stored in the diXa data warehouse with available chemical data. Since the end of the diXa project, ChemAgora has evolved into an independent portal, currently accessible directly through the ChemAgora home page, with improved search capabilities of online data sources.

  1. A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent

    DEFF Research Database (Denmark)

    Alifrangis, Michael; Enosse, Sonia; Pearce, Richard

    2005-01-01

    Single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum dihydrofolate reductase (dhfr), and dihydropteroate synthetase (dhps), and chloroquine resistance transporter (Pfcrt) genes are used as molecular markers of P. falciparum resistance to sulfadoxine/pyrimethamine and chloroquine....... However, to be a practical tool in the surveillance of drug resistance, simpler methods for high-throughput haplotyping are warranted. Here we describe a quick and simple technique that detects dhfr, dhps, and Pfcrt SNPs using polymerase chain reaction (PCR)- and enzyme-linked immunosorbent assay (ELISA...

  2. Effect of a Body Model on Performance in a Virtual Environment Search Task

    National Research Council Canada - National Science Library

    Singer, Michael

    1998-01-01

    ...) in training dismounted soldiers. This experiment investigated full body representation (generic) versus a hand linked pointer on movement performance in an office building interior during a search task...

  3. A Linked Science Investigation: Enhancing Climate Change Data Discovery with Semantic Technologies.

    Science.gov (United States)

    Pouchard, Line C; Branstetter, Marcia L; Cook, Robert B; Devarakonda, Ranjeet; Green, Jim; Palanisamy, Giri; Alexander, Paul; Noy, Natalya F

    2013-09-01

    Linked Science is the practice of inter-connecting scientific assets by publishing, sharing and linking scientific data and processes in end-to-end loosely coupled workflows that allow the sharing and re-use of scientific data. Much of this data does not live in the cloud or on the Web, but rather in multi-institutional data centers that provide tools and add value through quality assurance, validation, curation, dissemination, and analysis of the data. In this paper, we make the case for the use of scientific scenarios in Linked Science. We propose a scenario in river-channel transport that requires biogeochemical experimental data and global climate-simulation model data from many sources. We focus on the use of ontologies-formal machine-readable descriptions of the domain-to facilitate search and discovery of this data. Mercury, developed at Oak Ridge National Laboratory, is a tool for distributed metadata harvesting, search and retrieval. Mercury currently provides uniform access to more than 100,000 metadata records; 30,000 scientists use it each month. We augmented search in Mercury with ontologies, such as the ontologies in the Semantic Web for Earth and Environmental Terminology (SWEET) collection by prototyping a component that provides access to the ontology terms from Mercury. We evaluate the coverage of SWEET for the ORNL Distributed Active Archive Center (ORNL DAAC).

  4. Unusual Features of Crystal Structures of Some Simple Copper Compounds

    Science.gov (United States)

    Douglas, Bodie

    2009-01-01

    Some simple copper compounds have unusual crystal structures. Cu[subscript 3]N is cubic with N atoms at centers of octahedra formed by 6 Cu atoms. Cu[subscript 2]O (cuprite) is also cubic; O atoms are in tetrahedra formed by 4 Cu atoms. These tetrahedra are linked by sharing vertices forming two independent networks without linkages between them.…

  5. Linked Ocean Data

    Science.gov (United States)

    Leadbetter, Adam; Arko, Robert; Chandler, Cynthia; Shepherd, Adam

    2014-05-01

    Data repositories. The benefits of this approach include: increased interoperability between the metadata created by projects; improved data discovery as users of SeaDataNet, R2R and BCO-DMO terms can find data using labels with which they are familiar both standard tools and newly developed custom tools may be used to explore the data; and using standards means the custom tools are easier to develop Linked Data is a concept which has been in existence for nearly a decade, and has a simple set of formal best practices associated with it. Linked Data is increasingly being seen as a driver of the next generation of "community science" activities. While many data providers in the oceanographic domain may be unaware of Linked Data, they may also be providing it at one of its lower levels. Here we have shown that it is possible to deliver the highest standard of Linked Oceanographic Data, and some of the benefits of the approach.

  6. Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults.

    Science.gov (United States)

    Carson-Chahhoud, Kristin V; Wakai, Abel; van Agteren, Joseph Em; Smith, Brian J; McCabe, Grainne; Brinn, Malcolm P; O'Sullivan, Ronan

    2017-09-07

    For management of pneumothorax that occurs without underlying lung disease, also referred to as primary spontaneous pneumothorax, simple aspiration is technically easier to perform than intercostal tube drainage. In this systematic review, we seek to compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax. This review was first published in 2007 and was updated in 2017. To compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax. We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 1) in the Cochrane Library; MEDLINE (1966 to January 2017); and Embase (1980 to January 2017). We searched the World Health Organization (WHO) International Clinical Trials Registry for ongoing trials (January 2017). We checked the reference lists of included trials and contacted trial authors. We imposed no language restrictions. We included randomized controlled trials (RCTs) of adults 18 years of age and older with primary spontaneous pneumothorax that compared simple aspiration versus intercostal tube drainage. Two review authors independently selected studies for inclusion, assessed trial quality, and extracted data. We combined studies using the random-effects model. Of 2332 publications obtained through the search strategy, seven studies met the inclusion criteria; one study was ongoing and six studies of 435 participants were eligible for inclusion in the updated review. Data show a significant difference in immediate success rates of procedures favouring tube drainage over simple aspiration for management of primary spontaneous pneumothorax (risk ratio (RR) 0.78, 95% confidence interval (CI) 0.69 to 0.89; 435 participants, 6 studies; moderate-quality evidence). Duration of hospitalization however was significantly less for patients treated by simple aspiration (mean

  7. RASOnD - A comprehensive resource and search tool for RAS superfamily oncogenes from various species

    Directory of Open Access Journals (Sweden)

    Singh Tej P

    2011-07-01

    Full Text Available Abstract Background The Ras superfamily plays an important role in the control of cell signalling and division. Mutations in the Ras genes convert them into active oncogenes. The Ras oncogenes form a major thrust of global cancer research as they are involved in the development and progression of tumors. This has resulted in the exponential growth of data on Ras superfamily across different public databases and in literature. However, no dedicated public resource is currently available for data mining and analysis on this family. The present database was developed to facilitate straightforward accession, retrieval and analysis of information available on Ras oncogenes from one particular site. Description We have developed the RAS Oncogene Database (RASOnD as a comprehensive knowledgebase that provides integrated and curated information on a single platform for oncogenes of Ras superfamily. RASOnD encompasses exhaustive genomics and proteomics data existing across diverse publicly accessible databases. This resource presently includes overall 199,046 entries from 101 different species. It provides a search tool to generate information about their nucleotide and amino acid sequences, single nucleotide polymorphisms, chromosome positions, orthologies, motifs, structures, related pathways and associated diseases. We have implemented a number of user-friendly search interfaces and sequence analysis tools. At present the user can (i browse the data (ii search any field through a simple or advance search interface and (iii perform a BLAST search and subsequently CLUSTALW multiple sequence alignment by selecting sequences of Ras oncogenes. The Generic gene browser, GBrowse, JMOL for structural visualization and TREEVIEW for phylograms have been integrated for clear perception of retrieved data. External links to related databases have been included in RASOnD. Conclusions This database is a resource and search tool dedicated to Ras oncogenes. It has

  8. OpenSearch technology for geospatial resources discovery

    Science.gov (United States)

    Papeschi, Fabrizio; Enrico, Boldrini; Mazzetti, Paolo

    2010-05-01

    set of services for discovery, access, and processing of geospatial resources in a SOA framework. GI-cat is a distributed CSW framework implementation developed by the ESSI Lab of the Italian National Research Council (CNR-IMAA) and the University of Florence. It provides brokering and mediation functionalities towards heterogeneous resources and inventories, exposing several standard interfaces for query distribution. This work focuses on a new GI-cat interface which allows the catalog to be queried according to the OpenSearch syntax specification, thus filling the gap between the SOA architectural design of the CSW and the Web 2.0. At the moment, there is no OGC standard specification about this topic, but an official change request has been proposed in order to enable the OGC catalogues to support OpenSearch queries. In this change request, an OpenSearch extension is proposed providing a standard mechanism to query a resource based on temporal and geographic extents. Two new catalog operations are also proposed, in order to publish a suitable OpenSearch interface. This extended interface is implemented by the modular GI-cat architecture adding a new profiling module called "OpenSearch profiler". Since GI-cat also acts as a clearinghouse catalog, another component called "OpenSearch accessor" is added in order to access OpenSearch compliant services. An important role in the GI-cat extension, is played by the adopted mapping strategy. Two different kind of mappings are required: query, and response elements mapping. Query mapping is provided in order to fit the simple OpenSearch query syntax to the complex CSW query expressed by the OGC Filter syntax. GI-cat internal data model is based on the ISO-19115 profile, that is more complex than the simple XML syndication formats, such as RSS 2.0 and Atom 1.0, suggested by OpenSearch. Once response elements are available, in order to be presented, they need to be translated from the GI-cat internal data model, to the above

  9. "Multisensory brand search: How the meaning of sounds guides consumers' visual attention": Correction to Knoeferle et al. (2016).

    Science.gov (United States)

    2017-03-01

    Reports an error in "Multisensory brand search: How the meaning of sounds guides consumers' visual attention" by Klemens M. Knoeferle, Pia Knoeferle, Carlos Velasco and Charles Spence ( Journal of Experimental Psychology: Applied , 2016[Jun], Vol 22[2], 196-210). In the article, under Experiment 2, Design and Stimuli, the set number of target products and visual distractors reported in the second paragraph should be 20 and 13, respectively: "On each trial, the 16 products shown in the display were randomly selected from a set of 20 products belonging to different categories. Out of the set of 20 products, seven were potential targets, whereas the other 13 were used as visual distractors only throughout the experiment (since they were not linked to specific usage or consumption sounds)." Consequently, Appendix A in the supplemental materials has been updated. (The following abstract of the original article appeared in record 2016-28876-002.) Building on models of crossmodal attention, the present research proposes that brand search is inherently multisensory, in that the consumers' visual search for a specific brand can be facilitated by semantically related stimuli that are presented in another sensory modality. A series of 5 experiments demonstrates that the presentation of spatially nonpredictive auditory stimuli associated with products (e.g., usage sounds or product-related jingles) can crossmodally facilitate consumers' visual search for, and selection of, products. Eye-tracking data (Experiment 2) revealed that the crossmodal effect of auditory cues on visual search manifested itself not only in RTs, but also in the earliest stages of visual attentional processing, thus suggesting that the semantic information embedded within sounds can modulate the perceptual saliency of the target products' visual representations. Crossmodal facilitation was even observed for newly learnt associations between unfamiliar brands and sonic logos, implicating multisensory short

  10. Non-constant link tension coefficient in the tumbling-snake model subjected to simple shear

    Science.gov (United States)

    Stephanou, Pavlos S.; Kröger, Martin

    2017-11-01

    The authors of the present study have recently presented evidence that the tumbling-snake model for polymeric systems has the necessary capacity to predict the appearance of pronounced undershoots in the time-dependent shear viscosity as well as an absence of equally pronounced undershoots in the transient two normal stress coefficients. The undershoots were found to appear due to the tumbling behavior of the director u when a rotational Brownian diffusion term is considered within the equation of motion of polymer segments, and a theoretical basis concerning the use of a link tension coefficient given through the nematic order parameter had been provided. The current work elaborates on the quantitative predictions of the tumbling-snake model to demonstrate its capacity to predict undershoots in the time-dependent shear viscosity. These predictions are shown to compare favorably with experimental rheological data for both polymer melts and solutions, help us to clarify the microscopic origin of the observed phenomena, and demonstrate in detail why a constant link tension coefficient has to be abandoned.

  11. InChI in the wild: an assessment of InChIKey searching in Google

    Science.gov (United States)

    2013-01-01

    While chemical databases can be queried using the InChI string and InChIKey (IK) the latter was designed for open-web searching. It is becoming increasingly effective for this since more sources enhance crawling of their websites by the Googlebot and consequent IK indexing. Searchers who use Google as an adjunct to database access may be less familiar with the advantages of using the IK as explored in this review. As an example, the IK for atorvastatin retrieves ~200 low-redundancy links from a Google search in 0.3 of a second. These include most major databases and a very low false-positive rate. Results encompass less familiar but potentially useful sources and can be extended to isomer capture by using just the skeleton layer of the IK. Google Advanced Search can be used to filter large result sets. Image searching with the IK is also effective and complementary to open-web queries. Results can be particularly useful for less-common structures as exemplified by a major metabolite of atorvastatin giving only three hits. Testing also demonstrated document-to-document and document-to-database joins via structure matching. The necessary generation of an IK from chemical names can be accomplished using open tools and resources for patents, papers, abstracts or other text sources. Active global sharing of local IK-linked information can be accomplished via surfacing in open laboratory notebooks, blogs, Twitter, figshare and other routes. While information-rich chemistry (e.g. approved drugs) can exhibit swamping and redundancy effects, the much smaller IK result sets for link-poor structures become a transformative first-pass option. The IK indexing has therefore turned Google into a de-facto open global chemical information hub by merging links to most significant sources, including over 50 million PubChem and ChemSpider records. The simplicity, specificity and speed of matching make it a useful option for biologists or others less familiar with chemical searching

  12. Transitionless driving on adiabatic search algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Sangchul, E-mail: soh@qf.org.qa [Qatar Environment and Energy Research Institute, Qatar Foundation, Doha (Qatar); Kais, Sabre, E-mail: kais@purdue.edu [Qatar Environment and Energy Research Institute, Qatar Foundation, Doha (Qatar); Department of Chemistry, Department of Physics and Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907 (United States)

    2014-12-14

    We study quantum dynamics of the adiabatic search algorithm with the equivalent two-level system. Its adiabatic and non-adiabatic evolution is studied and visualized as trajectories of Bloch vectors on a Bloch sphere. We find the change in the non-adiabatic transition probability from exponential decay for the short running time to inverse-square decay in asymptotic running time. The scaling of the critical running time is expressed in terms of the Lambert W function. We derive the transitionless driving Hamiltonian for the adiabatic search algorithm, which makes a quantum state follow the adiabatic path. We demonstrate that a uniform transitionless driving Hamiltonian, approximate to the exact time-dependent driving Hamiltonian, can alter the non-adiabatic transition probability from the inverse square decay to the inverse fourth power decay with the running time. This may open up a new but simple way of speeding up adiabatic quantum dynamics.

  13. Biomechanical Comparison of Standard and Linked Single-Row Rotator Cuff Repairs in a Human Cadaver Model.

    Science.gov (United States)

    Meisel, Adam F; Henninger, Heath B; Barber, F Alan; Getelman, Mark H

    2017-05-01

    The purpose of this study was to evaluate the time zero cyclic and failure loading properties of a linked single-row rotator cuff repair compared with a standard simple suture single-row repair using triple-loaded suture anchors. Eighteen human cadaveric shoulders from 9 matched pairs were dissected, and full-thickness supraspinatus tears were created. The tendon cross-sectional area was recorded. In each pair, one side was repaired with a linked single-row construct and the other with a simple suture single-row construct, both using 2 triple-loaded suture anchors. After preloading, specimens were cycled to 1 MPa of effective stress at 1 Hz for 500 cycles, and gap formation was recorded with a digital video system. Samples were then loaded to failure, and modes of failure were recorded. There was no statistical difference in peak gap formation between the control and linked constructs (3.6 ± 0.9 mm and 3.6 ± 1.2 mm, respectively; P = .697). Both constructs averaged below a 5-mm cyclic failure threshold. There was no statistical difference in ultimate load to failure between the control and linked repair (511.1 ± 139.0 N and 561.2 ± 131.8 N, respectively; P = .164), and both groups reached failure at loads similar to previous studies. Constructs failed predominantly via tissue tearing parallel to the medial suture line. The linked repair performed similarly to the simple single-row repair. Both constructs demonstrated high ultimate load to failure and good resistance to gap formation with cyclic loading, validating the time zero strength of both constructs in a human cadaveric model. The linked repair provided equivalent resistance to gap formation and failure loads compared with simple suture single-row repairs with triple-loaded suture anchors. This suggests that the linked repair is a simplified rip-stop configuration using the existing suture that may perform similarly to current rotator cuff repair techniques. Copyright © 2016 Arthroscopy

  14. Investigating the role of visual and auditory search in reading and developmental dyslexia

    Directory of Open Access Journals (Sweden)

    Marie eLallier

    2013-09-01

    Full Text Available It has been suggested that auditory and visual sequential processing deficits contribute to phonological disorders in developmental dyslexia. As an alternative explanation to a phonological deficit as the proximal cause for reading disorders, the visual attention span hypothesis (VA Span suggests that difficulties in processing visual elements simultaneously lead to dyslexia, regardless of the presence of a phonological disorder. In this study, we assessed whether deficits in processing simultaneously displayed visual or auditory elements is linked to dyslexia associated with a VA Span impairment. Sixteen children with developmental dyslexia and 16 age-matched skilled readers were assessed on visual and auditory search tasks. Participants were asked to detect a target presented simultaneously with 3, 9 or 15 distracters. In the visual modality, target detection was slower in the dyslexic children than in the control group on a serial search condition only: the intercepts (but not the slopes of the search functions were higher in the dyslexic group than in the control group. In the auditory modality, although no group difference was observed, search performance was influenced by the number of distracters in the control group only. Within the dyslexic group, not only poor visual search (high reaction times and intercepts but also low auditory search performance (d´ strongly correlated with poor irregular word reading accuracy. Moreover, both visual and auditory search performance was associated with the VA Span abilities of dyslexic participants but not with their phonological skills. The present data suggests that some visual mechanisms engaged in serial search contribute to reading and orthographic knowledge via VA Span skills regardless of phonological skills. The present results further open the question of the role of auditory simultaneous processing in reading as well as its link with VA Span skills.

  15. Investigating the role of visual and auditory search in reading and developmental dyslexia.

    Science.gov (United States)

    Lallier, Marie; Donnadieu, Sophie; Valdois, Sylviane

    2013-01-01

    It has been suggested that auditory and visual sequential processing deficits contribute to phonological disorders in developmental dyslexia. As an alternative explanation to a phonological deficit as the proximal cause for reading disorders, the visual attention span hypothesis (VA Span) suggests that difficulties in processing visual elements simultaneously lead to dyslexia, regardless of the presence of a phonological disorder. In this study, we assessed whether deficits in processing simultaneously displayed visual or auditory elements is linked to dyslexia associated with a VA Span impairment. Sixteen children with developmental dyslexia and 16 age-matched skilled readers were assessed on visual and auditory search tasks. Participants were asked to detect a target presented simultaneously with 3, 9, or 15 distracters. In the visual modality, target detection was slower in the dyslexic children than in the control group on a "serial" search condition only: the intercepts (but not the slopes) of the search functions were higher in the dyslexic group than in the control group. In the auditory modality, although no group difference was observed, search performance was influenced by the number of distracters in the control group only. Within the dyslexic group, not only poor visual search (high reaction times and intercepts) but also low auditory search performance (d') strongly correlated with poor irregular word reading accuracy. Moreover, both visual and auditory search performance was associated with the VA Span abilities of dyslexic participants but not with their phonological skills. The present data suggests that some visual mechanisms engaged in "serial" search contribute to reading and orthographic knowledge via VA Span skills regardless of phonological skills. The present results further open the question of the role of auditory simultaneous processing in reading as well as its link with VA Span skills.

  16. Quantifying the semantics of search behavior before stock market moves.

    Science.gov (United States)

    Curme, Chester; Preis, Tobias; Stanley, H Eugene; Moat, Helen Susannah

    2014-08-12

    Technology is becoming deeply interwoven into the fabric of society. The Internet has become a central source of information for many people when making day-to-day decisions. Here, we present a method to mine the vast data Internet users create when searching for information online, to identify topics of interest before stock market moves. In an analysis of historic data from 2004 until 2012, we draw on records from the search engine Google and online encyclopedia Wikipedia as well as judgments from the service Amazon Mechanical Turk. We find evidence of links between Internet searches relating to politics or business and subsequent stock market moves. In particular, we find that an increase in search volume for these topics tends to precede stock market falls. We suggest that extensions of these analyses could offer insight into large-scale information flow before a range of real-world events.

  17. Labor tax reform and equilibrium unemployment : a search and matching approach

    NARCIS (Netherlands)

    Heijdra, Ben J.; Ligthart, Jenny E.

    2004-01-01

    The paper studies simple strategies of labor tax reform in a search and matching model of the labor market featuring endogenous labor supply. Changing the composition of the tax wedge---that is, reducing a payroll tax and increasing a progressive wage tax such that the marginal tax wedge remains

  18. Labor Tax Reform and Equilibrium Unemployment : A Search and Matching Approach

    NARCIS (Netherlands)

    Heijdra, B.J.; Ligthart, J.E.

    2004-01-01

    The paper studies simple strategies of labor tax reform in a search and matching model of the labor market featuring endogenous labor supply.Changing the composition of the tax wedge|that is, reducing a payroll tax and increasing a progressive wage tax such that the marginal tax wedge remains

  19. Dark-matter QCD-axion searches.

    Science.gov (United States)

    Rosenberg, Leslie J

    2015-10-06

    In the late 20th century, cosmology became a precision science. Now, at the beginning of the next century, the parameters describing how our universe evolved from the Big Bang are generally known to a few percent. One key parameter is the total mass density of the universe. Normal matter constitutes only a small fraction of the total mass density. Observations suggest this additional mass, the dark matter, is cold (that is, moving nonrelativistically in the early universe) and interacts feebly if at all with normal matter and radiation. There's no known such elementary particle, so the strong presumption is the dark matter consists of particle relics of a new kind left over from the Big Bang. One of the most important questions in science is the nature of this dark matter. One attractive particle dark-matter candidate is the axion. The axion is a hypothetical elementary particle arising in a simple and elegant extension to the standard model of particle physics that nulls otherwise observable CP-violating effects (where CP is the product of charge reversal C and parity inversion P) in quantum chromo dynamics (QCD). A light axion of mass 10(-(6-3)) eV (the invisible axion) would couple extraordinarily weakly to normal matter and radiation and would therefore be extremely difficult to detect in the laboratory. However, such an axion is a compelling dark-matter candidate and is therefore a target of a number of searches. Compared with other particle dark-matter candidates, the plausible range of axion dark-matter couplings and masses is narrowly constrained. This focused search range allows for definitive searches, where a nonobservation would seriously impugn the dark-matter QCD-axion hypothesis. Axion searches use a wide range of technologies, and the experiment sensitivities are now reaching likely dark-matter axion couplings and masses. This article is a selective overview of the current generation of sensitive axion searches. Not all techniques and experiments

  20. Building a better search engine for earth science data

    Science.gov (United States)

    Armstrong, E. M.; Yang, C. P.; Moroni, D. F.; McGibbney, L. J.; Jiang, Y.; Huang, T.; Greguska, F. R., III; Li, Y.; Finch, C. J.

    2017-12-01

    Free text data searching of earth science datasets has been implemented with varying degrees of success and completeness across the spectrum of the 12 NASA earth sciences data centers. At the JPL Physical Oceanography Distributed Active Archive Center (PO.DAAC) the search engine has been developed around the Solr/Lucene platform. Others have chosen other popular enterprise search platforms like Elasticsearch. Regardless, the default implementations of these search engines leveraging factors such as dataset popularity, term frequency and inverse document term frequency do not fully meet the needs of precise relevancy and ranking of earth science search results. For the PO.DAAC, this shortcoming has been identified for several years by its external User Working Group that has assigned several recommendations to improve the relevancy and discoverability of datasets related to remotely sensed sea surface temperature, ocean wind, waves, salinity, height and gravity that comprise a total count of over 500 public availability datasets. Recently, the PO.DAAC has teamed with an effort led by George Mason University to improve the improve the search and relevancy ranking of oceanographic data via a simple search interface and powerful backend services called MUDROD (Mining and Utilizing Dataset Relevancy from Oceanographic Datasets to Improve Data Discovery) funded by the NASA AIST program. MUDROD has mined and utilized the combination of PO.DAAC earth science dataset metadata, usage metrics, and user feedback and search history to objectively extract relevance for improved data discovery and access. In addition to improved dataset relevance and ranking, the MUDROD search engine also returns recommendations to related datasets and related user queries. This presentation will report on use cases that drove the architecture and development, and the success metrics and improvements on search precision and recall that MUDROD has demonstrated over the existing PO.DAAC search

  1. Digest: Demographic inferences accounting for selection at linked sites†.

    Science.gov (United States)

    Simon, Alexis; Duranton, Maud

    2018-05-16

    Complex demography and selection at linked sites can generate spurious signatures of divergent selection. Unfortunately, many attempts at demographic inference consider overly simple models and neglect the effect of selection at linked sites. In this issue, Rougemont and Bernatchez (2018) applied an approximate Bayesian computation (ABC) framework that accounts for indirect selection to reveal a complex history of secondary contacts in Atlantic salmon (Salmo salar) that might explain a high rate of latitudinal clines in this species. © 2018 The Author(s). Evolution © 2018 The Society for the Study of Evolution.

  2. Visual search guidance is best after a short delay.

    Science.gov (United States)

    Schmidt, Joseph; Zelinsky, Gregory J

    2011-03-25

    Search displays are typically presented immediately after a target cue, but in the real-world, delays often exist between target designation and search. Experiments 1 and 2 asked how search guidance changes with delay. Targets were cued using a picture or text label, each for 3000ms, followed by a delay up to 9000ms before the search display. Search stimuli were realistic objects, and guidance was quantified using multiple eye movement measures. Text-based cues showed a non-significant trend towards greater guidance following any delay relative to a no-delay condition. However, guidance from a pictorial cue increased sharply 300-600ms after preview offset. Experiment 3 replicated this guidance enhancement using shorter preview durations while equating the time from cue onset to search onset, demonstrating that the guidance benefit is linked to preview offset rather than a more complete encoding of the target. Experiment 4 showed that enhanced guidance persists even with a mask flashed at preview offset, suggesting an explanation other than visual priming. We interpret our findings as evidence for the rapid consolidation of target information into a guiding representation, which attains its maximum effectiveness shortly after preview offset. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Searching and Extracting Data from the EMBL-EBI Complex Portal.

    Science.gov (United States)

    Meldal, Birgit H M; Orchard, Sandra

    2018-01-01

    The Complex Portal ( www.ebi.ac.uk/complexportal ) is an encyclopedia of macromolecular complexes. Complexes are assigned unique, stable IDs, are species specific, and list all participating members with links to an appropriate reference database (UniProtKB, ChEBI, RNAcentral). Each complex is annotated extensively with its functions, properties, structure, stoichiometry, tissue expression profile, and subcellular location. Links to domain-specific databases allow the user to access additional information and enable data searching and filtering. Complexes can be saved and downloaded in PSI-MI XML, MI-JSON, and tab-delimited formats.

  4. Improving multivariate Horner schemes with Monte Carlo tree search

    Science.gov (United States)

    Kuipers, J.; Plaat, A.; Vermaseren, J. A. M.; van den Herik, H. J.

    2013-11-01

    Optimizing the cost of evaluating a polynomial is a classic problem in computer science. For polynomials in one variable, Horner's method provides a scheme for producing a computationally efficient form. For multivariate polynomials it is possible to generalize Horner's method, but this leaves freedom in the order of the variables. Traditionally, greedy schemes like most-occurring variable first are used. This simple textbook algorithm has given remarkably efficient results. Finding better algorithms has proved difficult. In trying to improve upon the greedy scheme we have implemented Monte Carlo tree search, a recent search method from the field of artificial intelligence. This results in better Horner schemes and reduces the cost of evaluating polynomials, sometimes by factors up to two.

  5. Searches for very rare decays of kaons

    Energy Technology Data Exchange (ETDEWEB)

    Lang, K. [Univ. of Texas, Austin, TX (United States)

    1997-01-01

    The physics motivation for searches for very rare kaon decays, either forbidden or suppressed within the Standard Model, is briefly discussed. Simple arguments conclude that such searches probe possible new forces at a 200 TeV mass scale or constitute a precision test of the electroweak model. The examples of such process are decays of K{sub L}{sup 0} {yields} {mu} {sup {+-}}e{sup -+}, K{sup +} {yields} {pi}{sup +} {mu}{sup +} e{sup -}, K{sub L}{sup 0} {yields} {mu}{sup +} {mu}{sup -}, and K{sup +} {yields} {pi} {yields} {pi}{sup +}{nu}{bar {nu}}. We present the current experimental status and describe the new efforts to reach sensitivities down to one part in 10{sup 12}. The discussion is focused on the experimental program at the Alternating Gradient Synchrotron at Brookhaven National Laboratory, where intense beams make such studies possible.

  6. ACADEMIC TRAINING LECTURE SERIES: Searching for Supersymmetry at the LHC

    CERN Multimedia

    2003-01-01

    3, 4, 5, 6, 7 February 2003 ACADEMIC TRAINING LECTURE SERIES from 10.00 to 12.00 hrs - Auditorium, bldg. 500 Searching for Supersymmetry at the LHC by F. Gianotti, CERN-EP and G. Ridolfi, Univ. Di Genova, Italy We will review the general motivations for proposing non-standard descriptions of fundamental interactions. We will give a simple and pedagogical presentation of the theoretical foundations of Supersymmetry, and we will describe the main features of a realistic supersymmetric extension of the Standard Model. We will present the phenomenology expected in several motivated scenarios. We will then review the present status of the experimental searches for Supersymmetry at LEP and Tevatron, and discuss prospects at future machines with emphasis on the LHC. We will outline the search strategies and the analysis methods, and compare the sensitivity and reach of the various machines.

  7. Gravitational wave searches using the DSN (Deep Space Network)

    International Nuclear Information System (INIS)

    Nelson, S.J.; Armstrong, J.W.

    1988-01-01

    The Deep Space Network Doppler spacecraft link is currently the only method available for broadband gravitational wave searches in the 0.01 to 0.001 Hz frequency range. The DSN's role in the worldwide search for gravitational waves is described by first summarizing from the literature current theoretical estimates of gravitational wave strengths and time scales from various astrophysical sources. Current and future detection schemes for ground based and space based detectors are then discussed. Past, present, and future planned or proposed gravitational wave experiments using DSN Doppler tracking are described. Lastly, some major technical challenges to improve gravitational wave sensitivities using the DSN are discussed

  8. Andromeda: a peptide search engine integrated into the MaxQuant environment.

    Science.gov (United States)

    Cox, Jürgen; Neuhauser, Nadin; Michalski, Annette; Scheltema, Richard A; Olsen, Jesper V; Mann, Matthias

    2011-04-01

    A key step in mass spectrometry (MS)-based proteomics is the identification of peptides in sequence databases by their fragmentation spectra. Here we describe Andromeda, a novel peptide search engine using a probabilistic scoring model. On proteome data, Andromeda performs as well as Mascot, a widely used commercial search engine, as judged by sensitivity and specificity analysis based on target decoy searches. Furthermore, it can handle data with arbitrarily high fragment mass accuracy, is able to assign and score complex patterns of post-translational modifications, such as highly phosphorylated peptides, and accommodates extremely large databases. The algorithms of Andromeda are provided. Andromeda can function independently or as an integrated search engine of the widely used MaxQuant computational proteomics platform and both are freely available at www.maxquant.org. The combination enables analysis of large data sets in a simple analysis workflow on a desktop computer. For searching individual spectra Andromeda is also accessible via a web server. We demonstrate the flexibility of the system by implementing the capability to identify cofragmented peptides, significantly improving the total number of identified peptides.

  9. High activity and Levy searches: jellyfish can search the water column like fish.

    Science.gov (United States)

    Hays, Graeme C; Bastian, Thomas; Doyle, Thomas K; Fossette, Sabrina; Gleiss, Adrian C; Gravenor, Michael B; Hobson, Victoria J; Humphries, Nicolas E; Lilley, Martin K S; Pade, Nicolas G; Sims, David W

    2012-02-07

    Over-fishing may lead to a decrease in fish abundance and a proliferation of jellyfish. Active movements and prey search might be thought to provide a competitive advantage for fish, but here we use data-loggers to show that the frequently occurring coastal jellyfish (Rhizostoma octopus) does not simply passively drift to encounter prey. Jellyfish (327 days of data from 25 jellyfish with depth collected every 1 min) showed very dynamic vertical movements, with their integrated vertical movement averaging 619.2 m d(-1), more than 60 times the water depth where they were tagged. The majority of movement patterns were best approximated by exponential models describing normal random walks. However, jellyfish also showed switching behaviour from exponential patterns to patterns best fitted by a truncated Lévy distribution with exponents (mean μ=1.96, range 1.2-2.9) close to the theoretical optimum for searching for sparse prey (μopt≈2.0). Complex movements in these 'simple' animals may help jellyfish to compete effectively with fish for plankton prey, which may enhance their ability to increase in dominance in perturbed ocean systems.

  10. Using turbocodes on optical links

    Directory of Open Access Journals (Sweden)

    Glenn Claes

    2006-04-01

    Full Text Available The fast evolving telecommunication world is permanently in search for faster and better communication links. On one hand, turbo codes are like a dream come true. Due to their amazing performance, they have become the reference in the word of error detecting and correcting codes. On the other hand, broadband transmission channels like optical fibres can meet the need for higher transmission velocity. In this paper therefore we will bring these two elements together and thus the performance of turbocodes on optical links will be studied. First the turbocode will be optimised throughout an individual analysis of each of its design parameters. Moreover it wil be shown that turbocodes have much better performance than the well known Reed-Solomon codes. Finally we will show that the 8Bit/10Bit code, which is required to comply with the Gigabit Ethernet standard, becomes superfluous when working with turbocodes. All tests were carried out on multimode graded-index glass fibres.

  11. Incites into Citation Linking using the OAI-PMH

    CERN Multimedia

    CERN. Geneva

    2005-01-01

    There are some 300 repositories of research material (Source: IAR), most of which have an OAI-PMH interface, but no current Institutional Repositories export reference data - nor do they provide their users with citation impact metrics. We propose a model for extending IR's to be citation aware and to expose that data to citation indices using the OAI-PMH and OpenURL. We present some techniques for the export of citation data using the OAI-PMH in Citebase Search. As part of a proposed Open Access Citation Information study we have developed a proposal for the integration of reference parsing and linking into the author- deposit process. This highly-distributed approach to citation linking utilises the OAI-PMH to transfer structured citation data between IRs and citation indexing services. OpenURL - a standard for contextual linking using bibliographic data - is now a NISO standard. As well as it's linking role, OpenURL is a useful standard for the transfer of bibliographic data for the purposes of citation in...

  12. In search of psychosocial variables linked to the recidivism in young offenders.

    Directory of Open Access Journals (Sweden)

    María del Carmen Cano

    2011-01-01

    Full Text Available Most of the literature on juvenile delinquency is aimed to the identification of the protective and risk factors of the antisocial and criminal behaviors. In this line, a study was carried out to assess whether the family setting, personal variables of the youngster and variables linked to the judicial measure execution mediate in recidivism. For this reason, all the closed judicial files of the young offenders from the Service of Juvenile Justice in Jaén (Spain have been analysed. The results showed that such family setting variables as broken homes, large families, low incomes, deprived neighborhoods, criminal records, drug abuse, children protection records and crime legitimacy are linked to recidivism. As for personal variables of the youngster, the findings illustrate that re-offenders are characterized by external attribution, deficits in social skills, deficits in self-control, violent behaviors and low tolerance to frustration. In relation to the judicial measure execution variables, data support that the non re-offenders are defined in contrast to re-offenders, by a high compliance with rules and timetables and with the established objectives, as well as a high family involvement during the judicial measure execution. The implications of the results for prevention of recidivism are discussed.

  13. Shuttle Planning for Link Closures in Urban Public Transport Networks

    DEFF Research Database (Denmark)

    van der Hurk, Evelien; Koutsopoulos, Haris N.; Wilson, Nigel

    2016-01-01

    Urban public transport systems must periodically close certain links for maintenance, which can have significant effects on the service provided to passengers. In practice, the effects of closures are mitigated by replacing the closed links with a simple shuttle service. However, alternative...... cost, which includes transfers and frequency-dependent waiting time costs. This model is applied to a shuttle design problem based on a real-world case study of the Massachusetts Bay Transportation Authority network of Boston, Massachusetts. The results show that additional shuttle routes can reduce...

  14. 'Sciencenet'--towards a global search and share engine for all scientific knowledge.

    Science.gov (United States)

    Lütjohann, Dominic S; Shah, Asmi H; Christen, Michael P; Richter, Florian; Knese, Karsten; Liebel, Urban

    2011-06-15

    Modern biological experiments create vast amounts of data which are geographically distributed. These datasets consist of petabytes of raw data and billions of documents. Yet to the best of our knowledge, a search engine technology that searches and cross-links all different data types in life sciences does not exist. We have developed a prototype distributed scientific search engine technology, 'Sciencenet', which facilitates rapid searching over this large data space. By 'bringing the search engine to the data', we do not require server farms. This platform also allows users to contribute to the search index and publish their large-scale data to support e-Science. Furthermore, a community-driven method guarantees that only scientific content is crawled and presented. Our peer-to-peer approach is sufficiently scalable for the science web without performance or capacity tradeoff. The free to use search portal web page and the downloadable client are accessible at: http://sciencenet.kit.edu. The web portal for index administration is implemented in ASP.NET, the 'AskMe' experiment publisher is written in Python 2.7, and the backend 'YaCy' search engine is based on Java 1.6.

  15. Using a neural network in the search for the Higgs boson

    International Nuclear Information System (INIS)

    Hultqvist, K.; Jacobsson, R.; Johansson, K.E.

    1995-01-01

    The search for the Standard Model Higgs boson in high energy e + e - collisions requires analysis techniques which efficiently discriminate against the very large background. A classifier based on a feed-forward neural network has been extensively used in a search in the channel where the Higgs boson is produced in association with neutrinos. The method has significantly improved the sensitivity of the search. With a simple preselection based on event topology followed by a neural network we have obtained a combined background rejection factor of more than 29 000 and a selection efficiency for Higgs particle events of 54%, assuming a mass of 55 GeV/c 2 for the Higgs boson. We describe here the details of the analysis with emphasis on the neural network. (orig.)

  16. MetaboSearch: tool for mass-based metabolite identification using multiple databases.

    Directory of Open Access Journals (Sweden)

    Bin Zhou

    Full Text Available Searching metabolites against databases according to their masses is often the first step in metabolite identification for a mass spectrometry-based untargeted metabolomics study. Major metabolite databases include Human Metabolome DataBase (HMDB, Madison Metabolomics Consortium Database (MMCD, Metlin, and LIPID MAPS. Since each one of these databases covers only a fraction of the metabolome, integration of the search results from these databases is expected to yield a more comprehensive coverage. However, the manual combination of multiple search results is generally difficult when identification of hundreds of metabolites is desired. We have implemented a web-based software tool that enables simultaneous mass-based search against the four major databases, and the integration of the results. In addition, more complete chemical identifier information for the metabolites is retrieved by cross-referencing multiple databases. The search results are merged based on IUPAC International Chemical Identifier (InChI keys. Besides a simple list of m/z values, the software can accept the ion annotation information as input for enhanced metabolite identification. The performance of the software is demonstrated on mass spectrometry data acquired in both positive and negative ionization modes. Compared with search results from individual databases, MetaboSearch provides better coverage of the metabolome and more complete chemical identifier information.The software tool is available at http://omics.georgetown.edu/MetaboSearch.html.

  17. Metadata Creation, Management and Search System for your Scientific Data

    Science.gov (United States)

    Devarakonda, R.; Palanisamy, G.

    2012-12-01

    Mercury Search Systems is a set of tools for creating, searching, and retrieving of biogeochemical metadata. Mercury toolset provides orders of magnitude improvements in search speed, support for any metadata format, integration with Google Maps for spatial queries, multi-facetted type search, search suggestions, support for RSS (Really Simple Syndication) delivery of search results, and enhanced customization to meet the needs of the multiple projects that use Mercury. Mercury's metadata editor provides a easy way for creating metadata and Mercury's search interface provides a single portal to search for data and information contained in disparate data management systems, each of which may use any metadata format including FGDC, ISO-19115, Dublin-Core, Darwin-Core, DIF, ECHO, and EML. Mercury harvests metadata and key data from contributing project servers distributed around the world and builds a centralized index. The search interfaces then allow the users to perform a variety of fielded, spatial, and temporal searches across these metadata sources. This centralized repository of metadata with distributed data sources provides extremely fast search results to the user, while allowing data providers to advertise the availability of their data and maintain complete control and ownership of that data. Mercury is being used more than 14 different projects across 4 federal agencies. It was originally developed for NASA, with continuing development funded by NASA, USGS, and DOE for a consortium of projects. Mercury search won the NASA's Earth Science Data Systems Software Reuse Award in 2008. References: R. Devarakonda, G. Palanisamy, B.E. Wilson, and J.M. Green, "Mercury: reusable metadata management data discovery and access system", Earth Science Informatics, vol. 3, no. 1, pp. 87-94, May 2010. R. Devarakonda, G. Palanisamy, J.M. Green, B.E. Wilson, "Data sharing and retrieval using OAI-PMH", Earth Science Informatics DOI: 10.1007/s12145-010-0073-0, (2010);

  18. Predicting cryptic links in host-parasite networks.

    Directory of Open Access Journals (Sweden)

    Tad Dallas

    2017-05-01

    Full Text Available Networks are a way to represent interactions among one (e.g., social networks or more (e.g., plant-pollinator networks classes of nodes. The ability to predict likely, but unobserved, interactions has generated a great deal of interest, and is sometimes referred to as the link prediction problem. However, most studies of link prediction have focused on social networks, and have assumed a completely censused network. In biological networks, it is unlikely that all interactions are censused, and ignoring incomplete detection of interactions may lead to biased or incorrect conclusions. Previous attempts to predict network interactions have relied on known properties of network structure, making the approach sensitive to observation errors. This is an obvious shortcoming, as networks are dynamic, and sometimes not well sampled, leading to incomplete detection of links. Here, we develop an algorithm to predict missing links based on conditional probability estimation and associated, node-level features. We validate this algorithm on simulated data, and then apply it to a desert small mammal host-parasite network. Our approach achieves high accuracy on simulated and observed data, providing a simple method to accurately predict missing links in networks without relying on prior knowledge about network structure.

  19. Simple machines

    CERN Document Server

    Graybill, George

    2007-01-01

    Just how simple are simple machines? With our ready-to-use resource, they are simple to teach and easy to learn! Chocked full of information and activities, we begin with a look at force, motion and work, and examples of simple machines in daily life are given. With this background, we move on to different kinds of simple machines including: Levers, Inclined Planes, Wedges, Screws, Pulleys, and Wheels and Axles. An exploration of some compound machines follows, such as the can opener. Our resource is a real time-saver as all the reading passages, student activities are provided. Presented in s

  20. A simple nonlinear dynamical computing device

    International Nuclear Information System (INIS)

    Miliotis, Abraham; Murali, K.; Sinha, Sudeshna; Ditto, William L.; Spano, Mark L.

    2009-01-01

    We propose and characterize an iterated map whose nonlinearity has a simple (i.e., minimal) electronic implementation. We then demonstrate explicitly how all the different fundamental logic gates can be implemented and morphed using this nonlinearity. These gates provide the full set of gates necessary to construct a general-purpose, reconfigurable computing device. As an example of how such chaotic computing devices can be exploited, we use an array of these maps to encode data and to process information. Each map can store one of M items, where M is variable and can be large. This nonlinear hardware stores data naturally in different bases or alphabets. We also show how this method of storing information can serve as a preprocessing tool for exact or inexact pattern-matching searches.

  1. Visual search performance in infants associates with later ASD diagnosis

    Directory of Open Access Journals (Sweden)

    C.H.M. Cheung

    2018-01-01

    Full Text Available An enhanced ability to detect visual targets amongst distractors, known as visual search (VS, has often been documented in Autism Spectrum Disorders (ASD. Yet, it is unclear when this behaviour emerges in development and if it is specific to ASD. We followed up infants at high and low familial risk for ASD to investigate how early VS abilities links to later ASD diagnosis, the potential underlying mechanisms of this association and the specificity of superior VS to ASD. Clinical diagnosis of ASD as well as dimensional measures of ASD, attention-deficit/hyperactivity disorder (ADHD and anxiety symptoms were ascertained at 3 years. At 9 and 15 months, but not at age 2 years, high-risk children who later met clinical criteria for ASD (HR-ASD had better VS performance than those without later diagnosis and low-risk controls. Although HR-ASD children were also more attentive to the task at 9 months, this did not explain search performance. Superior VS specifically predicted 3 year-old ASD but not ADHD or anxiety symptoms. Our results demonstrate that atypical perception and core ASD symptoms of social interaction and communication are closely and selectively associated during early development, and suggest causal links between perceptual and social features of ASD. Keywords: Visual search, Visual attention, ASD, ADHD, Infant, Familial risk

  2. Iterated local search and record-to-record travel applied to the fixed charge transportation problem

    DEFF Research Database (Denmark)

    Andersen, Jeanne; Klose, Andreas

    The fixed charge transportation problem (FCTP) is a well-known and difficult optimization problem with lots of applications in logistics. It consists in finding a minimum cost network flow from a set of suppliers to a set of customers. Beside costs proportional to quantities transported......, transportation costs do, however, include a fixed charge. Iterated local search and record-to-record travel are both simple local search based meta-heuristics that, to our knowledge, not yet have been applied to the FCTP. In this paper, we apply both types of search strategies and combine them into a single...

  3. Joint LIGO and TAMA300 search for gravitational waves from inspiralling neutron star binaries

    International Nuclear Information System (INIS)

    Abbott, B.; Abbott, R.; Adhikari, R.; Agresti, J.; Anderson, S.B.; Araya, M.; Armandula, H.; Asiri, F.; Barish, B.C.; Barnes, M.; Barton, M.A.; Bhawal, B.; Billingsley, G.; Black, E.; Blackburn, K.; Bork, R.; Brown, D.A.; Busby, D.; Cardenas, L.; Chandler, A.

    2006-01-01

    We search for coincident gravitational wave signals from inspiralling neutron star binaries using LIGO and TAMA300 data taken during early 2003. Using a simple trigger exchange method, we perform an intercollaboration coincidence search during times when TAMA300 and only one of the LIGO sites were operational. We find no evidence of any gravitational wave signals. We place an observational upper limit on the rate of binary neutron star coalescence with component masses between 1 and 3M · of 49 per year per Milky Way equivalent galaxy at a 90% confidence level. The methods developed during this search will find application in future network inspiral analyses

  4. Assessment of UVA-Riboflavin Corneal Cross-Linking Using Small Amplitude Oscillatory Shear Measurements.

    Science.gov (United States)

    Aslanides, Ioannis M; Dessi, Claudia; Georgoudis, Panagiotis; Charalambidis, Georgios; Vlassopoulos, Dimitris; Coutsolelos, Athanassios G; Kymionis, George; Mukherjee, Achyut; Kitsopoulos, Theofanis N

    2016-04-01

    The effect of ultraviolet (UV)-riboflavin cross-linking (CXL) has been measured primarily using the strip extensometry technique. We propose a simple and reliable methodology for the assessment of CXL treatment by using an established rheologic protocol based on small amplitude oscillatory shear (SAOS) measurements. It provides information on the average cross-link density and the elastic modulus of treated cornea samples. Three fresh postmortem porcine corneas were used to study the feasibility of the technique, one serving as control and two receiving corneal collagen cross-linking treatment. Subsequently, five pairs of fresh postmortem porcine corneas received corneal collagen cross-linking treatment with riboflavin and UVA-irradiation (370 nm; irradiance of 3 mW/cm2) for 30 minutes (Dresden protocol); the contralateral porcine corneas were used as control samples. After the treatment, the linear viscoelastic moduli of the corneal samples were measured using SAOS measurements and the average cross-linking densities extracted. For all cases investigated, the dynamic moduli of the cross-linked corneas were higher compared to those of the corresponding control samples. The increase of the elastic modulus of the treated samples was between 122% and 1750%. The difference was statistically significant for all tested samples (P = 0.018, 2-tailed t-test). We report a simple and accurate methodology for quantifying the effects of cross-linking on porcine corneas treated with the Dresden protocol by means of SAOS measurements in the linear regime. The measured dynamic moduli, elastic and viscous modulus, represent the energy storage and energy dissipation, respectively. Hence, they provide a means to assess the changing physical properties of the cross-linked collagen networks after CXL treatment.

  5. COMPARISON OF SIMPLE SUM AND DIVISIA MONETARY AGGREGATES USING PANEL DATA ANALYSIS

    Directory of Open Access Journals (Sweden)

    Sadullah CELIK

    2009-07-01

    Full Text Available It is well documented that financial innovation has led to poor performance of simple sum method of monetary aggregation destabilizing the historical relationship between monetary aggregates and ultimate target variables like rate of growth and rate of unemployment during the liberalization period of 1980s. This study tries to emphasize the superiority of an alternative method of aggregation over the simple sum method, namely Divisia monetary aggregates, employing panel data analysis for United States, United Kingdom, Euro Area and Japan for the period between 1980Q1 and 1993Q3. After investigating the order of stationarity of the panel data set through several panel unit root tests, we perform advanced panel cointegration tests to check the existence of a long run link between the Divisia monetary aggregates and income and interest rates in a simple Keynesian money demand function.

  6. Comparing image search behaviour in the ARRS GoldMiner search engine and a clinical PACS/RIS.

    Science.gov (United States)

    De-Arteaga, Maria; Eggel, Ivan; Do, Bao; Rubin, Daniel; Kahn, Charles E; Müller, Henning

    2015-08-01

    Information search has changed the way we manage knowledge and the ubiquity of information access has made search a frequent activity, whether via Internet search engines or increasingly via mobile devices. Medical information search is in this respect no different and much research has been devoted to analyzing the way in which physicians aim to access information. Medical image search is a much smaller domain but has gained much attention as it has different characteristics than search for text documents. While web search log files have been analysed many times to better understand user behaviour, the log files of hospital internal systems for search in a PACS/RIS (Picture Archival and Communication System, Radiology Information System) have rarely been analysed. Such a comparison between a hospital PACS/RIS search and a web system for searching images of the biomedical literature is the goal of this paper. Objectives are to identify similarities and differences in search behaviour of the two systems, which could then be used to optimize existing systems and build new search engines. Log files of the ARRS GoldMiner medical image search engine (freely accessible on the Internet) containing 222,005 queries, and log files of Stanford's internal PACS/RIS search called radTF containing 18,068 queries were analysed. Each query was preprocessed and all query terms were mapped to the RadLex (Radiology Lexicon) terminology, a comprehensive lexicon of radiology terms created and maintained by the Radiological Society of North America, so the semantic content in the queries and the links between terms could be analysed, and synonyms for the same concept could be detected. RadLex was mainly created for the use in radiology reports, to aid structured reporting and the preparation of educational material (Lanlotz, 2006) [1]. In standard medical vocabularies such as MeSH (Medical Subject Headings) and UMLS (Unified Medical Language System) specific terms of radiology are often

  7. Using relational databases for improved sequence similarity searching and large-scale genomic analyses.

    Science.gov (United States)

    Mackey, Aaron J; Pearson, William R

    2004-10-01

    Relational databases are designed to integrate diverse types of information and manage large sets of search results, greatly simplifying genome-scale analyses. Relational databases are essential for management and analysis of large-scale sequence analyses, and can also be used to improve the statistical significance of similarity searches by focusing on subsets of sequence libraries most likely to contain homologs. This unit describes using relational databases to improve the efficiency of sequence similarity searching and to demonstrate various large-scale genomic analyses of homology-related data. This unit describes the installation and use of a simple protein sequence database, seqdb_demo, which is used as a basis for the other protocols. These include basic use of the database to generate a novel sequence library subset, how to extend and use seqdb_demo for the storage of sequence similarity search results and making use of various kinds of stored search results to address aspects of comparative genomic analysis.

  8. Simplified validation of borderline hits of database searches

    OpenAIRE

    Thomas, Henrik; Shevchenko, Andrej

    2008-01-01

    Along with unequivocal hits produced by matching multiple MS/MS spectra to database sequences, LC-MS/MS analysis often yields a large number of hits of borderline statistical confidence. To simplify their validation, we propose to use rapid de novo interpretation of all acquired MS/MS spectra and, with the help of a simple software tool, display the candidate sequences together with each database search hit. We demonstrate that comparing hit database sequences and independent de novo interpre...

  9. Semantically Enriching the Search System of a Music Digital Library

    Science.gov (United States)

    de Juan, Paloma; Iglesias, Carlos

    Traditional search systems are usually based on keywords, a very simple and convenient mechanism to express a need for information. This is the most popular way of searching the Web, although it is not always an easy task to accurately summarize a natural language query in a few keywords. Working with keywords means losing the context, which is the only thing that can help us deal with ambiguity. This is the biggest problem of keyword-based systems. Semantic Web technologies seem a perfect solution to this problem, since they make it possible to represent the semantics of a given domain. In this chapter, we present three projects, Harmos, Semusici and Cantiga, whose aim is to provide access to a music digital library. We will describe two search systems, a traditional one and a semantic one, developed in the context of these projects and compare them in terms of usability and effectiveness.

  10. Search | CRDI - Centre de recherches pour le développement ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Mobile Nav Footer Links. Carrières · Nous joindre · S'abonner · Se désabonner · Droits d'auteur · Politique de libre accès · Politique de confidentialité · Éthique de la recherche · Transparence · Utilisation du site Web · Accueil · Search · Google ...

  11. Performance Analysis of FSO Links over Unified Gamma-Gamma Turbulence Channels

    KAUST Repository

    Ansari, Imran Shafique

    2015-05-01

    In this work, we present a unified performance analysis of a free-space optical (FSO) link that accounts for pointing errors and both types of detection techniques (i.e. intensity modulation/direct detection as well as heterodyne detection). We, then, present unified exact closed-form expressions for various statistical characteristics of the end-to-end signal-to-noise ratio (SNR) of a single link FSO transmission system. We capitalize on these unified results to offer unified exact closed-form expressions for various performance metrics. Additionally, we derive the asymptotic results for all the expressions derived earlier in the high SNR regime in terms of simple elementary functions. We also derive new asymptotic expressions for the ergodic capacity in the low as well as high SNR regimes in terms of simple elementary functions via utilizing moments. All the presented results are verified via computer-based Monte-Carlo simulations. © 2015 IEEE.

  12. The evolution of sex differences in mate searching when females benefit: new theory and a comparative test.

    Science.gov (United States)

    McCartney, J; Kokko, H; Heller, K-G; Gwynne, D T

    2012-03-22

    Sexual selection is thought to have led to searching as a profitable, but risky way of males obtaining mates. While there is great variation in which sex searches, previous theory has not considered search evolution when both males and females benefit from multiple mating. We present new theory and link it with data to bridge this gap. Two different search protocols exist between species in the bush-cricket genus Poecilimon (Orthoptera): females search for calling males, or males search for calling females. Poecilimon males also transfer a costly nuptial food gift to their mates during mating. We relate variations in searching protocols to variation in nuptial gift size among 32 Poecilimon taxa. As predicted, taxa where females search produce significantly larger nuptial gifts than those where males search. Our model and results show that search roles can reverse when multiple mating brings about sufficiently strong material benefits to females.

  13. Crowded visual search in children with normal vision and children with visual impairment.

    Science.gov (United States)

    Huurneman, Bianca; Cox, Ralf F A; Vlaskamp, Björn N S; Boonstra, F Nienke

    2014-03-01

    This study investigates the influence of oculomotor control, crowding, and attentional factors on visual search in children with normal vision ([NV], n=11), children with visual impairment without nystagmus ([VI-nys], n=11), and children with VI with accompanying nystagmus ([VI+nys], n=26). Exclusion criteria for children with VI were: multiple impairments and visual acuity poorer than 20/400 or better than 20/50. Three search conditions were presented: a row with homogeneous distractors, a matrix with homogeneous distractors, and a matrix with heterogeneous distractors. Element spacing was manipulated in 5 steps from 2 to 32 minutes of arc. Symbols were sized 2 times the threshold acuity to guarantee visibility for the VI groups. During simple row and matrix search with homogeneous distractors children in the VI+nys group were less accurate than children with NV at smaller spacings. Group differences were even more pronounced during matrix search with heterogeneous distractors. Search times were longer in children with VI compared to children with NV. The more extended impairments during serial search reveal greater dependence on oculomotor control during serial compared to parallel search. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Multimodal neuroimaging evidence linking memory and attention systems during visual search cued by context.

    Science.gov (United States)

    Kasper, Ryan W; Grafton, Scott T; Eckstein, Miguel P; Giesbrecht, Barry

    2015-03-01

    Visual search can be facilitated by the learning of spatial configurations that predict the location of a target among distractors. Neuropsychological and functional magnetic resonance imaging (fMRI) evidence implicates the medial temporal lobe (MTL) memory system in this contextual cueing effect, and electroencephalography (EEG) studies have identified the involvement of visual cortical regions related to attention. This work investigated two questions: (1) how memory and attention systems are related in contextual cueing; and (2) how these systems are involved in both short- and long-term contextual learning. In one session, EEG and fMRI data were acquired simultaneously in a contextual cueing task. In a second session conducted 1 week later, EEG data were recorded in isolation. The fMRI results revealed MTL contextual modulations that were correlated with short- and long-term behavioral context enhancements and attention-related effects measured with EEG. An fMRI-seeded EEG source analysis revealed that the MTL contributed the most variance to the variability in the attention enhancements measured with EEG. These results support the notion that memory and attention systems interact to facilitate search when spatial context is implicitly learned. © 2015 New York Academy of Sciences.

  15. COORDINATE-BASED META-ANALYTIC SEARCH FOR THE SPM NEUROIMAGING PIPELINE

    DEFF Research Database (Denmark)

    Wilkowski, Bartlomiej; Szewczyk, Marcin; Rasmussen, Peter Mondrup

    2009-01-01

    . BredeQuery offers a direct link from SPM5 to the Brede Database coordinate-based search engine. BredeQuery is able to ‘grab’ brain location coordinates from the SPM windows and enter them as a query for the Brede Database. Moreover, results of the query can be displayed in an SPM window and/or exported...

  16. Optimal design of link systems using successive zooming genetic algorithm

    Science.gov (United States)

    Kwon, Young-Doo; Sohn, Chang-hyun; Kwon, Soon-Bum; Lim, Jae-gyoo

    2009-07-01

    Link-systems have been around for a long time and are still used to control motion in diverse applications such as automobiles, robots and industrial machinery. This study presents a procedure involving the use of a genetic algorithm for the optimal design of single four-bar link systems and a double four-bar link system used in diesel engine. We adopted the Successive Zooming Genetic Algorithm (SZGA), which has one of the most rapid convergence rates among global search algorithms. The results are verified by experiment and the Recurdyn dynamic motion analysis package. During the optimal design of single four-bar link systems, we found in the case of identical input/output (IO) angles that the initial and final configurations show certain symmetry. For the double link system, we introduced weighting factors for the multi-objective functions, which minimize the difference between output angles, providing balanced engine performance, as well as the difference between final output angle and the desired magnitudes of final output angle. We adopted a graphical method to select a proper ratio between the weighting factors.

  17. Adding a Visualization Feature to Web Search Engines: It’s Time

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Pak C.

    2008-11-11

    Since the first world wide web (WWW) search engine quietly entered our lives in 1994, the “information need” behind web searching has rapidly grown into a multi-billion dollar business that dominates the internet landscape, drives e-commerce traffic, propels global economy, and affects the lives of the whole human race. Today’s search engines are faster, smarter, and more powerful than those released just a few years ago. With the vast investment pouring into research and development by leading web technology providers and the intense emotion behind corporate slogans such as “win the web” or “take back the web,” I can’t help but ask why are we still using the very same “text-only” interface that was used 13 years ago to browse our search engine results pages (SERPs)? Why has the SERP interface technology lagged so far behind in the web evolution when the corresponding search technology has advanced so rapidly? In this article I explore some current SERP interface issues, suggest a simple but practical visual-based interface design approach, and argue why a visual approach can be a strong candidate for tomorrow’s SERP interface.

  18. Improving e-book access via a library-developed full-text search tool.

    Science.gov (United States)

    Foust, Jill E; Bergen, Phillip; Maxeiner, Gretchen L; Pawlowski, Peter N

    2007-01-01

    This paper reports on the development of a tool for searching the contents of licensed full-text electronic book (e-book) collections. The Health Sciences Library System (HSLS) provides services to the University of Pittsburgh's medical programs and large academic health system. The HSLS has developed an innovative tool for federated searching of its e-book collections. Built using the XML-based Vivísimo development environment, the tool enables a user to perform a full-text search of over 2,500 titles from the library's seven most highly used e-book collections. From a single "Google-style" query, results are returned as an integrated set of links pointing directly to relevant sections of the full text. Results are also grouped into categories that enable more precise retrieval without reformulation of the search. A heuristic evaluation demonstrated the usability of the tool and a web server log analysis indicated an acceptable level of usage. Based on its success, there are plans to increase the number of online book collections searched. This library's first foray into federated searching has produced an effective tool for searching across large collections of full-text e-books and has provided a good foundation for the development of other library-based federated searching products.

  19. The Search Performance Evaluation and Prediction in Exploratory Search

    OpenAIRE

    LIU, FEI

    2016-01-01

    The exploratory search for complex search tasks requires an effective search behavior model to evaluate and predict user search performance. Few studies have investigated the relationship between user search behavior and search performance in exploratory search. This research adopts a mixed approach combining search system development, user search experiment, search query log analysis, and multivariate regression analysis to resolve the knowledge gap. Through this study, it is shown that expl...

  20. Optimal swimming strategies in mate searching pelagic copepods

    DEFF Research Database (Denmark)

    Kiørboe, Thomas

    2008-01-01

    Male copepods must swim to find females, but swimming increases the risk of meeting predators and is expensive in terms of energy expenditure. Here I address the trade-offs between gains and risks and the question of how much and how fast to swim using simple models that optimise the number...... of lifetime mate encounters. Radically different swimming strategies are predicted for different feeding behaviours, and these predictions are tested experimentally using representative species. In general, male swimming speeds and the difference in swimming speeds between the genders are predicted...... and observed to increase with increasing conflict between mate searching and feeding. It is high in ambush feeders, where searching (swimming) and feeding are mutually exclusive and low in species, where the matured males do not feed at all. Ambush feeding males alternate between stationary ambush feeding...

  1. Search for and study of linking transitions between super- and normal deformed wells in the {sup 151}Tb nucleus; Recherche et etude de transitions de liaison entre les puits super- et normalement deformes dans le noyau {sup 151}Tb

    Energy Technology Data Exchange (ETDEWEB)

    Robin, J

    2003-12-01

    While the superdeformation phenomenon has been observed many times in different mass regions, the excitation energy and angular momentum are not known for most of the superdeformed bands, mainly in the A {approx} 150 mass region. We have thus undertaken the search for and study of linking transitions between super and normal deformed potential wells in the Tb{sup 151} nucleus with the EUROBALL-IV spectrometer based at the subatomic research institute of Strasbourg. This nucleus presents the peculiarity of having an excited superdeformed band identical to the yrast one of Dy{sup 152}, which has recently been linked to normal deformed states. As the Dy{sup 152} nucleus exhibits a shape coexistence in the first potential well, we have also searched for collective rotational bands with prolate but moderate shape, coexisting with the oblate structure of Tb{sup 151}. The discovery of new superdeformed bands in the Tb{sup 151,152} isotopes, the extension to lower and higher spins of the previously known bands, and mean field calculations with a deformed Woods-Saxon potential have contributed to improve our knowledge as well as raise new questions on the orbitals configuration assignments of these bands. (author)

  2. Managing Your Team's Weakest Link.

    Science.gov (United States)

    Hills, Laura

    2015-01-01

    Do you have a poor-performing employee on your medical practice team? If so, you're not alone. Unfortunately, this is a problem that many medical practice managers face. This article describes the best strategies for managing your team's weakest link. It explores common yet very difficult circumstances that cause low employee performance and that test the patience, heart, and skills of a practice manager. It guides readers through a process of self-discovery to determine whether their negative biases or grudges may be causing employees to perform poorly. It suggests several possible other reasons for weak employee performance, including problems with the job, practice, leadership, communication, and fit between the employee and the job. This article also suggests the best strategy for communicating concerns about performance to the weakest-link employee. It offers guidance to practice managers about protecting their time and energy when handling a poor performer. It provides a simple formula for calculating the cost of a low-performing employee, 10 possible personal reasons for the employee's poor work performance, specific questions to ask to uncover the reasons for poor performance, and an eight-rule strategy for confronting poor performance effectively. Finally, this article offers practice managers a practical strategy for handling resistance from their weakest link, illustrated with a sample dialogue.

  3. One visual search, many memory searches: An eye-tracking investigation of hybrid search.

    Science.gov (United States)

    Drew, Trafton; Boettcher, Sage E P; Wolfe, Jeremy M

    2017-09-01

    Suppose you go to the supermarket with a shopping list of 10 items held in memory. Your shopping expedition can be seen as a combination of visual search and memory search. This is known as "hybrid search." There is a growing interest in understanding how hybrid search tasks are accomplished. We used eye tracking to examine how manipulating the number of possible targets (the memory set size [MSS]) changes how observers (Os) search. We found that dwell time on each distractor increased with MSS, suggesting a memory search was being executed each time a new distractor was fixated. Meanwhile, although the rate of refixation increased with MSS, it was not nearly enough to suggest a strategy that involves repeatedly searching visual space for subgroups of the target set. These data provide a clear demonstration that hybrid search tasks are carried out via a "one visual search, many memory searches" heuristic in which Os examine items in the visual array once with a very low rate of refixations. For each item selected, Os activate a memory search that produces logarithmic response time increases with increased MSS. Furthermore, the percentage of distractors fixated was strongly modulated by the MSS: More items in the MSS led to a higher percentage of fixated distractors. Searching for more potential targets appears to significantly alter how Os approach the task, ultimately resulting in more eye movements and longer response times.

  4. A Teaching Approach from the Exhaustive Search Method to the Needleman-Wunsch Algorithm

    Science.gov (United States)

    Xu, Zhongneng; Yang, Yayun; Huang, Beibei

    2017-01-01

    The Needleman-Wunsch algorithm has become one of the core algorithms in bioinformatics; however, this programming requires more suitable explanations for students with different major backgrounds. In supposing sample sequences and using a simple store system, the connection between the exhaustive search method and the Needleman-Wunsch algorithm…

  5. XSemantic: An Extension of LCA Based XML Semantic Search

    Science.gov (United States)

    Supasitthimethee, Umaporn; Shimizu, Toshiyuki; Yoshikawa, Masatoshi; Porkaew, Kriengkrai

    One of the most convenient ways to query XML data is a keyword search because it does not require any knowledge of XML structure or learning a new user interface. However, the keyword search is ambiguous. The users may use different terms to search for the same information. Furthermore, it is difficult for a system to decide which node is likely to be chosen as a return node and how much information should be included in the result. To address these challenges, we propose an XML semantic search based on keywords called XSemantic. On the one hand, we give three definitions to complete in terms of semantics. Firstly, the semantic term expansion, our system is robust from the ambiguous keywords by using the domain ontology. Secondly, to return semantic meaningful answers, we automatically infer the return information from the user queries and take advantage of the shortest path to return meaningful connections between keywords. Thirdly, we present the semantic ranking that reflects the degree of similarity as well as the semantic relationship so that the search results with the higher relevance are presented to the users first. On the other hand, in the LCA and the proximity search approaches, we investigated the problem of information included in the search results. Therefore, we introduce the notion of the Lowest Common Element Ancestor (LCEA) and define our simple rule without any requirement on the schema information such as the DTD or XML Schema. The first experiment indicated that XSemantic not only properly infers the return information but also generates compact meaningful results. Additionally, the benefits of our proposed semantics are demonstrated by the second experiment.

  6. Searching Life, the Universe and Everything? The Implementation of Summon at the University of Huddersfield

    Directory of Open Access Journals (Sweden)

    Graham Stone

    2010-08-01

    Full Text Available A review of the recent literature suggests that users prefer simple search interfaces such as Google. The implication here is that libraries often fail to make their resources discoverable and that this may in turn affect the perceived value of the library. Against the background of the ongoing national debate about user expectations, a project group at the University of Huddersfield was asked to investigate the current provision for electronic resources and to look at a solution which would ‘provide ease of searching and access for the user, whilst reducing the workload for systems and technical services and remaining within current budget levels’. As a direct result of this review, the University of Huddersfield was the first UK commercial adopter of Summon in the summer of 2009. The Summon web-scale discovery service from Serials Solutions provides a simple single-search box to the breadth of the library's collection, swiftly delivering simultaneous information and results from the local catalogue and remote electronic resources offering a real alternative to the traditional federated search. This paper will provide a case study of the implementation, evaluation and launch of this radical new service to users at the University of Huddersfield, by detailing the approaches used and lessons learned throughout the implementation period and making recommendations for future enhancements.

  7. Cross-linking for microbial keratitis

    Directory of Open Access Journals (Sweden)

    Jayesh Vazirani

    2013-01-01

    Full Text Available The success of collagen cross-linking as a clinical modality to modify the clinical course in keratoconus seems to have fueled the search for alternative applications for this treatment. Current clinical data on its efficacy is limited and laboratory data seems to indicate that it performs poorly against resistant strains of bacteria and against slow growing organisms. However, the biological plausibility of crosslinking and the lack of effective strategies in managing infections with these organisms continue to focus attention on this potential treatment. Well-conducted experimental and clinical studies with controls are required to answer the questions of its efficacy in future.

  8. Online games: a novel approach to explore how partial information influences human random searches

    Science.gov (United States)

    Martínez-García, Ricardo; Calabrese, Justin M.; López, Cristóbal

    2017-01-01

    Many natural processes rely on optimizing the success ratio of a search process. We use an experimental setup consisting of a simple online game in which players have to find a target hidden on a board, to investigate how the rounds are influenced by the detection of cues. We focus on the search duration and the statistics of the trajectories traced on the board. The experimental data are explained by a family of random-walk-based models and probabilistic analytical approximations. If no initial information is given to the players, the search is optimized for cues that cover an intermediate spatial scale. In addition, initial information about the extension of the cues results, in general, in faster searches. Finally, strategies used by informed players turn into non-stationary processes in which the length of e ach displacement evolves to show a well-defined characteristic scale that is not found in non-informed searches.

  9. From Schrцdinger's equation to the quantum search algorithm£

    Indian Academy of Sciences (India)

    Also the framework was simple and general and could be extended to ... It is unusual to write a paper listing the steps that led to a result after the result itself ... the quantum search algorithm – it is by no means a comprehensive review of quantum ..... D, as defined in the previous section, is no longer unitary for large ε.

  10. Polybinary modulation for bandwidth limited optical links

    DEFF Research Database (Denmark)

    Vegas Olmos, Juan José; Jurado-Navas, Antonio

    2015-01-01

    form of partial response modulation, employs simple codification and filtering at the transmitter to drastically increase the spectral efficiency. At the receiver side, poly binary modulation requires low complexity direct detection and very little digital signal processing. This talk will review...... the recent results on poly binary modulation, comprising both binary and multilevel signals as seed signals. The results will show how poly binary modulation effectively reduces the bandwidth requirements on optical links while providing high spectral efficiency....

  11. SearchResultFinder: federated search made easy

    NARCIS (Netherlands)

    Trieschnigg, Rudolf Berend; Tjin-Kam-Jet, Kien; Hiemstra, Djoerd

    Building a federated search engine based on a large number existing web search engines is a challenge: implementing the programming interface (API) for each search engine is an exacting and time-consuming job. In this demonstration we present SearchResultFinder, a browser plugin which speeds up

  12. Simple standard model extension by heavy charged scalar

    Science.gov (United States)

    Boos, E.; Volobuev, I.

    2018-05-01

    We consider a Standard Model (SM) extension by a heavy charged scalar gauged only under the UY(1 ) weak hypercharge gauge group. Such an extension, being gauge invariant with respect to the SM gauge group, is a simple special case of the well-known Zee model. Since the interactions of the charged scalar with the Standard Model fermions turn out to be significantly suppressed compared to the Standard Model interactions, the charged scalar provides an example of a long-lived charged particle being interesting to search for at the LHC. We present the pair and single production cross sections of the charged scalar at different colliders and the possible decay widths for various boson masses. It is shown that the current ATLAS and CMS searches at 8 and 13 TeV collision energy lead to the bounds on the scalar boson mass of about 300-320 GeV. The limits are expected to be much larger for higher collision energies and, assuming 15 a b-1 integrated luminosity, reach about 2.7 TeV at future 27 TeV LHC thus covering the most interesting mass region.

  13. Study on boundary search method for DFM mesh generation

    Directory of Open Access Journals (Sweden)

    Li Ri

    2012-08-01

    Full Text Available The boundary mesh of the casting model was determined by direct calculation on the triangular facets extracted from the STL file of the 3D model. Then the inner and outer grids of the model were identified by the algorithm in which we named Inner Seed Grid Method. Finally, a program to automatically generate a 3D FDM mesh was compiled. In the paper, a method named Triangle Contraction Search Method (TCSM was put forward to ensure not losing the boundary grids; while an algorithm to search inner seed grids to identify inner/outer grids of the casting model was also brought forward. Our algorithm was simple, clear and easy to construct program. Three examples for the casting mesh generation testified the validity of the program.

  14. Locating qualitative studies in dementia on MEDLINE, EMBASE, CINAHL, and PsycINFO: A comparison of search strategies.

    Science.gov (United States)

    Rogers, Morwenna; Bethel, Alison; Abbott, Rebecca

    2017-10-28

    Qualitative research in dementia improves understanding of the experience of people affected by dementia. Searching databases for qualitative studies is problematic. Qualitative-specific search strategies might help with locating studies. To examine the effectiveness (sensitivity and precision) of 5 qualitative strategies on locating qualitative research studies in dementia in 4 major databases (MEDLINE, EMBASE, PsycINFO, and CINAHL). Qualitative dementia studies were checked for inclusion on MEDLINE, EMBASE, PsycINFO, and CINAHL. Five qualitative search strategies (subject headings, simple free-text terms, complex free-text terms, and 2 broad-based strategies) were tested for study retrieval. Specificity, precision and number needed to read were calculated. Two hundred fourteen qualitative studies in dementia were included. PsycINFO and CINAHL held the most qualitative studies out the 4 databases studied (N = 171 and 166, respectively) and both held unique records (N = 14 and 7, respectively). The controlled vocabulary strategy in CINAHL returned 96% (N = 192) of studies held; by contrast, controlled vocabulary in PsycINFO returned 7% (N = 13) of studies held. The broad-based strategies returned more studies (93-99%) than the other free-text strategies (22-82%). Precision ranged from 0.061 to 0.004 resulting in a number needed to read to obtain 1 relevant study ranging from 16 (simple free-text search in CINAHL) to 239 (broad-based search in EMBASE). Qualitative search strategies using 3 broad terms were more sensitive than long complex searches. The controlled vocabulary for qualitative research in CINAHL was particularly effective. Furthermore, results indicate that MEDLINE and EMBASE offer little benefit for locating qualitative dementia research if CINAHL and PSYCINFO are also searched. Copyright © 2017 John Wiley & Sons, Ltd.

  15. search GenBank: interactive orchestration and ad-hoc choreography of Web services in the exploration of the biomedical resources of the National Center For Biotechnology Information.

    Science.gov (United States)

    Mrozek, Dariusz; Małysiak-Mrozek, Bożena; Siążnik, Artur

    2013-03-01

    Due to the growing number of biomedical entries in data repositories of the National Center for Biotechnology Information (NCBI), it is difficult to collect, manage and process all of these entries in one place by third-party software developers without significant investment in hardware and software infrastructure, its maintenance and administration. Web services allow development of software applications that integrate in one place the functionality and processing logic of distributed software components, without integrating the components themselves and without integrating the resources to which they have access. This is achieved by appropriate orchestration or choreography of available Web services and their shared functions. After the successful application of Web services in the business sector, this technology can now be used to build composite software tools that are oriented towards biomedical data processing. We have developed a new tool for efficient and dynamic data exploration in GenBank and other NCBI databases. A dedicated search GenBank system makes use of NCBI Web services and a package of Entrez Programming Utilities (eUtils) in order to provide extended searching capabilities in NCBI data repositories. In search GenBank users can use one of the three exploration paths: simple data searching based on the specified user's query, advanced data searching based on the specified user's query, and advanced data exploration with the use of macros. search GenBank orchestrates calls of particular tools available through the NCBI Web service providing requested functionality, while users interactively browse selected records in search GenBank and traverse between NCBI databases using available links. On the other hand, by building macros in the advanced data exploration mode, users create choreographies of eUtils calls, which can lead to the automatic discovery of related data in the specified databases. search GenBank extends standard capabilities of the

  16. Search Engine Customization and Data Set Builder

    OpenAIRE

    Arias Moreno, Fco Javier

    2009-01-01

    There are two core objectives in this work: firstly, to build a data set, and secondly, to customize a search engine. The first objective is to design and implement a data set builder. There are two steps required for this. The first step is to build a crawler. The second step is to include a cleaner. The crawler collects Web links. The cleaner extracts the main content and removes noise from the files crawled. The goal of this application is crawling Web news sites to find the...

  17. Artificial intelligence search techniques for optimization of the cold source geometry

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1988-01-01

    Most optimization studies of cold neutron sources have concentrated on the numerical prediction or experimental measurement of the cold moderator optimum thickness which produces the largest cold neutron leakage for a given thermal neutron source. Optimizing the geometrical shape of the cold source, however, is a more difficult problem because the optimized quantity, the cold neutron leakage, is an implicit function of the shape which is the unknown in such a study. We draw an analogy between this problem and a state space search, then we use a simple Artificial Intelligence (AI) search technique to determine the optimum cold source shape based on a two-group, r-z diffusion model. We implemented this AI design concept in the computer program AID which consists of two modules, a physical model module and a search module, which can be independently modified, improved, or made more sophisticated. 7 refs., 1 fig

  18. Artificial intelligence search techniques for the optimization of cold source geometry

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1988-01-01

    Most optimization studies of cold neutron sources have concentrated on the numerical prediction or experimental measurement of the cold moderator optimum thickness that produces the largest cold neutron leakage for a given thermal neutron source. Optimizing the geometric shape of the cold source, however, is a more difficult problem because the optimized quantity, the cold neutron leakage, is an implicit function of the shape, which is the unknown in such a study. An analogy is drawn between this problem and a state space search, then a simple artificial intelligence (AI) search technique is used to determine the optimum cold source shape based on a two-group, r-z diffusion model. This AI design concept was implemented in the computer program AID, which consists of two modules, a physical model module, and a search module, which can be independently modified, improved, or made more sophisticated

  19. Age differences in visual search for compound patterns: long- versus short-range grouping.

    Science.gov (United States)

    Burack, J A; Enns, J T; Iarocci, G; Randolph, B

    2000-11-01

    Visual search for compound patterns was examined in observers aged 6, 8, 10, and 22 years. The main question was whether age-related improvement in search rate (response time slope over number of items) was different for patterns defined by short- versus long-range spatial relations. Perceptual access to each type of relation was varied by using elements of same contrast (easy to access) or mixed contrast (hard to access). The results showed large improvements with age in search rate for long-range targets; search rate for short-range targets was fairly constant across age. This pattern held regardless of whether perceptual access to a target was easy or hard, supporting the hypothesis that different processes are involved in perceptual grouping at these two levels. The results also point to important links between ontogenic and microgenic change in perception (H. Werner, 1948, 1957).

  20. A literature search tool for intelligent extraction of disease-associated genes.

    Science.gov (United States)

    Jung, Jae-Yoon; DeLuca, Todd F; Nelson, Tristan H; Wall, Dennis P

    2014-01-01

    To extract disorder-associated genes from the scientific literature in PubMed with greater sensitivity for literature-based support than existing methods. We developed a PubMed query to retrieve disorder-related, original research articles. Then we applied a rule-based text-mining algorithm with keyword matching to extract target disorders, genes with significant results, and the type of study described by the article. We compared our resulting candidate disorder genes and supporting references with existing databases. We demonstrated that our candidate gene set covers nearly all genes in manually curated databases, and that the references supporting the disorder-gene link are more extensive and accurate than other general purpose gene-to-disorder association databases. We implemented a novel publication search tool to find target articles, specifically focused on links between disorders and genotypes. Through comparison against gold-standard manually updated gene-disorder databases and comparison with automated databases of similar functionality we show that our tool can search through the entirety of PubMed to extract the main gene findings for human diseases rapidly and accurately.

  1. The antibiotic resistance "mobilome": searching for the link between environment and clinic.

    Science.gov (United States)

    Perry, Julie A; Wright, Gerard D

    2013-01-01

    Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia. The environmental "resistome" is the collection of all genes that directly or indirectly contribute to antibiotic resistance. Many of these resistance determinants originate in antibiotic-producing organisms (where they serve to mediate self-immunity), while others become resistance determinants only when mobilized and over-expressed in non-native hosts (like plasmid-encoded β-lactamases). The modern environmental resistome is under selective pressure from human activities such as agriculture, which may influence the composition of the local resistome and lead to gene transfer events. Beyond the environment, we are challenged in the clinic by the rise in both frequency and diversity of antibiotic resistant pathogens. We assume that clinical resistance originated in the environment, but few examples of direct gene exchange between the environmental resistome and the clinical resistome have been documented. Strong evidence exists to suggest that clinical aminoglycoside and vancomycin resistance enzymes, the extended-spectrum β-lactamase CTX-M and the quinolone resistance gene qnr have direct links to the environmental resistome. In this review, we highlight recent advances in our understanding of horizontal gene transfer of antibiotic resistance genes from the environment to the clinic. Improvements in sequencing technologies coupled with functional metagenomic studies have revealed previously underappreciated diversity in the environmental resistome, and also established novel genetic links to the clinic. Understanding mechanisms of gene exchange becomes vital in controlling the future dissemination of antibiotic resistance.

  2. Complex dynamics of our economic life on different scales: insights from search engine query data.

    Science.gov (United States)

    Preis, Tobias; Reith, Daniel; Stanley, H Eugene

    2010-12-28

    Search engine query data deliver insight into the behaviour of individuals who are the smallest possible scale of our economic life. Individuals are submitting several hundred million search engine queries around the world each day. We study weekly search volume data for various search terms from 2004 to 2010 that are offered by the search engine Google for scientific use, providing information about our economic life on an aggregated collective level. We ask the question whether there is a link between search volume data and financial market fluctuations on a weekly time scale. Both collective 'swarm intelligence' of Internet users and the group of financial market participants can be regarded as a complex system of many interacting subunits that react quickly to external changes. We find clear evidence that weekly transaction volumes of S&P 500 companies are correlated with weekly search volume of corresponding company names. Furthermore, we apply a recently introduced method for quantifying complex correlations in time series with which we find a clear tendency that search volume time series and transaction volume time series show recurring patterns.

  3. Composite Octet Searches with Jet Substructure

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Yang; /SLAC; Shelton, Jessie; /Yale U.

    2012-02-14

    Many new physics models with strongly interacting sectors predict a mass hierarchy between the lightest vector meson and the lightest pseudoscalar mesons. We examine the power of jet substructure tools to extend the 7 TeV LHC sensitivity to these new states for the case of QCD octet mesons, considering both two gluon and two b-jet decay modes for the pseudoscalar mesons. We develop both a simple dijet search using only the jet mass and a more sophisticated jet substructure analysis, both of which can discover the composite octets in a dijet-like signature. The reach depends on the mass hierarchy between the vector and pseudoscalar mesons. We find that for the pseudoscalar-to-vector meson mass ratio below approximately 0.2 the simple jet mass analysis provides the best discovery limit; for a ratio between 0.2 and the QCD-like value of 0.3, the sophisticated jet substructure analysis has the best discovery potential; for a ratio above approximately 0.3, the standard four-jet analysis is more suitable.

  4. The Up-Link Problem: Using RytovProp for Beam Propagation Calculations--Conference Proceedings (Postprint)

    National Research Council Canada - National Science Library

    Fried, David L

    2008-01-01

    ...(s) of the effect of turbulence on optical propagation. This method has been applied to the evaluation of Up-Link performance delivery of laser power from a simple ground transmitter to a satellite...

  5. Using Linked Data to Annotate and Search Educational Video Resources for Supporting Distance Learning

    Science.gov (United States)

    Yu, Hong Qing; Pedrinaci, C.; Dietze, S.; Domingue, J.

    2012-01-01

    Multimedia educational resources play an important role in education, particularly for distance learning environments. With the rapid growth of the multimedia web, large numbers of educational video resources are increasingly being created by several different organizations. It is crucial to explore, share, reuse, and link these educational…

  6. Simple algorithm for improved security in the FDDI protocol

    Science.gov (United States)

    Lundy, G. M.; Jones, Benjamin

    1993-02-01

    We propose a modification to the Fiber Distributed Data Interface (FDDI) protocol based on a simple algorithm which will improve confidential communication capability. This proposed modification provides a simple and reliable system which exploits some of the inherent security properties in a fiber optic ring network. This method differs from conventional methods in that end to end encryption can be facilitated at the media access control sublayer of the data link layer in the OSI network model. Our method is based on a variation of the bit stream cipher method. The transmitting station takes the intended confidential message and uses a simple modulo two addition operation against an initialization vector. The encrypted message is virtually unbreakable without the initialization vector. None of the stations on the ring will have access to both the encrypted message and the initialization vector except the transmitting and receiving stations. The generation of the initialization vector is unique for each confidential transmission and thus provides a unique approach to the key distribution problem. The FDDI protocol is of particular interest to the military in terms of LAN/MAN implementations. Both the Army and the Navy are considering the standard as the basis for future network systems. A simple and reliable security mechanism with the potential to support realtime communications is a necessary consideration in the implementation of these systems. The proposed method offers several advantages over traditional methods in terms of speed, reliability, and standardization.

  7. PALNS - A software framework for parallel large neighborhood search

    DEFF Research Database (Denmark)

    Røpke, Stefan

    2009-01-01

    This paper propose a simple, parallel, portable software framework for the metaheuristic named large neighborhood search (LNS). The aim is to provide a framework where the user has to set up a few data structures and implement a few functions and then the framework provides a metaheuristic where ...... parallelization "comes for free". We apply the parallel LNS heuristic to two different problems: the traveling salesman problem with pickup and delivery (TSPPD) and the capacitated vehicle routing problem (CVRP)....

  8. Addressing special structure in the relevance feedback learning problem through aspect-based image search

    NARCIS (Netherlands)

    M.J. Huiskes (Mark)

    2004-01-01

    textabstractIn this paper we focus on a number of issues regarding special structure in the relevance feedback learning problem, most notably the effects of image selection based on partial relevance on the clustering behavior of examples. We propose a simple scheme, aspect-based image search, which

  9. Supervised learning of tools for content-based search of image databases

    Science.gov (United States)

    Delanoy, Richard L.

    1996-03-01

    A computer environment, called the Toolkit for Image Mining (TIM), is being developed with the goal of enabling users with diverse interests and varied computer skills to create search tools for content-based image retrieval and other pattern matching tasks. Search tools are generated using a simple paradigm of supervised learning that is based on the user pointing at mistakes of classification made by the current search tool. As mistakes are identified, a learning algorithm uses the identified mistakes to build up a model of the user's intentions, construct a new search tool, apply the search tool to a test image, display the match results as feedback to the user, and accept new inputs from the user. Search tools are constructed in the form of functional templates, which are generalized matched filters capable of knowledge- based image processing. The ability of this system to learn the user's intentions from experience contrasts with other existing approaches to content-based image retrieval that base searches on the characteristics of a single input example or on a predefined and semantically- constrained textual query. Currently, TIM is capable of learning spectral and textural patterns, but should be adaptable to the learning of shapes, as well. Possible applications of TIM include not only content-based image retrieval, but also quantitative image analysis, the generation of metadata for annotating images, data prioritization or data reduction in bandwidth-limited situations, and the construction of components for larger, more complex computer vision algorithms.

  10. Toddlers' language-mediated visual search: they need not have the words for it

    NARCIS (Netherlands)

    Johnson, E.K.; McQueen, J.M.; Hüttig, F.

    2011-01-01

    Eye movements made by listeners during language-mediated visual search reveal a strong link between visual processing and conceptual processing. For example, upon hearing the word for a missing referent with a characteristic colour (e.g., “strawberry”), listeners tend to fixate a colour-matched

  11. VisualRank: applying PageRank to large-scale image search.

    Science.gov (United States)

    Jing, Yushi; Baluja, Shumeet

    2008-11-01

    Because of the relative ease in understanding and processing text, commercial image-search systems often rely on techniques that are largely indistinguishable from text-search. Recently, academic studies have demonstrated the effectiveness of employing image-based features to provide alternative or additional signals. However, it remains uncertain whether such techniques will generalize to a large number of popular web queries, and whether the potential improvement to search quality warrants the additional computational cost. In this work, we cast the image-ranking problem into the task of identifying "authority" nodes on an inferred visual similarity graph and propose VisualRank to analyze the visual link structures among images. The images found to be "authorities" are chosen as those that answer the image-queries well. To understand the performance of such an approach in a real system, we conducted a series of large-scale experiments based on the task of retrieving images for 2000 of the most popular products queries. Our experimental results show significant improvement, in terms of user satisfaction and relevancy, in comparison to the most recent Google Image Search results. Maintaining modest computational cost is vital to ensuring that this procedure can be used in practice; we describe the techniques required to make this system practical for large scale deployment in commercial search engines.

  12. Reinforcement of smoking and drinking: tobacco marketing strategies linked with alcohol in the United States.

    Science.gov (United States)

    Jiang, Nan; Ling, Pamela M

    2011-10-01

    We investigated tobacco companies' knowledge about concurrent use of tobacco and alcohol, their marketing strategies linking cigarettes with alcohol, and the benefits tobacco companies sought from these marketing activities. We performed systematic searches on previously secret tobacco industry documents, and we summarized the themes and contexts of relevant search results. Tobacco company research confirmed the association between tobacco use and alcohol use. Tobacco companies explored promotional strategies linking cigarettes and alcohol, such as jointly sponsoring special events with alcohol companies to lower the cost of sponsorships, increase consumer appeal, reinforce brand identity, and generate increased cigarette sales. They also pursued promotions that tied cigarette sales to alcohol purchases, and cigarette promotional events frequently featured alcohol discounts or encouraged alcohol use. Tobacco companies' numerous marketing strategies linking cigarettes with alcohol may have reinforced the use of both substances. Because using tobacco and alcohol together makes it harder to quit smoking, policies prohibiting tobacco sales and promotion in establishments where alcohol is served and sold might mitigate this effect. Smoking cessation programs should address the effect that alcohol consumption has on tobacco use.

  13. Performance Analysis of Free-Space Optical Links Over Malaga (M) Turbulence Channels with Pointing Errors

    KAUST Repository

    Ansari, Imran Shafique

    2015-08-12

    In this work, we present a unified performance analysis of a free-space optical (FSO) link that accounts for pointing errors and both types of detection techniques (i.e. intensity modulation/direct detection (IM/DD) as well as heterodyne detection). More specifically, we present unified exact closedform expressions for the cumulative distribution function, the probability density function, the moment generating function, and the moments of the end-to-end signal-to-noise ratio (SNR) of a single link FSO transmission system, all in terms of the Meijer’s G function except for the moments that is in terms of simple elementary functions. We then capitalize on these unified results to offer unified exact closed-form expressions for various performance metrics of FSO link transmission systems, such as, the outage probability, the scintillation index (SI), the average error rate for binary and M-ary modulation schemes, and the ergodic capacity (except for IM/DD technique, where we present closed-form lower bound results), all in terms of Meijer’s G functions except for the SI that is in terms of simple elementary functions. Additionally, we derive the asymptotic results for all the expressions derived earlier in terms of Meijer’s G function in the high SNR regime in terms of simple elementary functions via an asymptotic expansion of the Meijer’s G function. We also derive new asymptotic expressions for the ergodic capacity in the low as well as high SNR regimes in terms of simple elementary functions via utilizing moments. All the presented results are verified via computer-based Monte-Carlo simulations.

  14. Performance Analysis of Free-Space Optical Links Over Malaga (M) Turbulence Channels with Pointing Errors

    KAUST Repository

    Ansari, Imran Shafique; Yilmaz, Ferkan; Alouini, Mohamed-Slim

    2015-01-01

    In this work, we present a unified performance analysis of a free-space optical (FSO) link that accounts for pointing errors and both types of detection techniques (i.e. intensity modulation/direct detection (IM/DD) as well as heterodyne detection). More specifically, we present unified exact closedform expressions for the cumulative distribution function, the probability density function, the moment generating function, and the moments of the end-to-end signal-to-noise ratio (SNR) of a single link FSO transmission system, all in terms of the Meijer’s G function except for the moments that is in terms of simple elementary functions. We then capitalize on these unified results to offer unified exact closed-form expressions for various performance metrics of FSO link transmission systems, such as, the outage probability, the scintillation index (SI), the average error rate for binary and M-ary modulation schemes, and the ergodic capacity (except for IM/DD technique, where we present closed-form lower bound results), all in terms of Meijer’s G functions except for the SI that is in terms of simple elementary functions. Additionally, we derive the asymptotic results for all the expressions derived earlier in terms of Meijer’s G function in the high SNR regime in terms of simple elementary functions via an asymptotic expansion of the Meijer’s G function. We also derive new asymptotic expressions for the ergodic capacity in the low as well as high SNR regimes in terms of simple elementary functions via utilizing moments. All the presented results are verified via computer-based Monte-Carlo simulations.

  15. Improving e-book access via a library-developed full-text search tool*

    Science.gov (United States)

    Foust, Jill E.; Bergen, Phillip; Maxeiner, Gretchen L.; Pawlowski, Peter N.

    2007-01-01

    Purpose: This paper reports on the development of a tool for searching the contents of licensed full-text electronic book (e-book) collections. Setting: The Health Sciences Library System (HSLS) provides services to the University of Pittsburgh's medical programs and large academic health system. Brief Description: The HSLS has developed an innovative tool for federated searching of its e-book collections. Built using the XML-based Vivísimo development environment, the tool enables a user to perform a full-text search of over 2,500 titles from the library's seven most highly used e-book collections. From a single “Google-style” query, results are returned as an integrated set of links pointing directly to relevant sections of the full text. Results are also grouped into categories that enable more precise retrieval without reformulation of the search. Results/Evaluation: A heuristic evaluation demonstrated the usability of the tool and a web server log analysis indicated an acceptable level of usage. Based on its success, there are plans to increase the number of online book collections searched. Conclusion: This library's first foray into federated searching has produced an effective tool for searching across large collections of full-text e-books and has provided a good foundation for the development of other library-based federated searching products. PMID:17252065

  16. Open meta-search with OpenSearch: a case study

    OpenAIRE

    O'Riordan, Adrian P.

    2007-01-01

    The goal of this project was to demonstrate the possibilities of open source search engine and aggregation technology in a Web environment by building a meta-search engine which employs free open search engines and open protocols. In contrast many meta-search engines on the Internet use proprietary search systems. The search engines employed in this case study are all based on the OpenSearch protocol. OpenSearch-compliant systems support XML technologies such as RSS and Atom for aggregation a...

  17. Multisensory brand search: How the meaning of sounds guides consumers' visual attention.

    Science.gov (United States)

    Knoeferle, Klemens M; Knoeferle, Pia; Velasco, Carlos; Spence, Charles

    2016-06-01

    Building on models of crossmodal attention, the present research proposes that brand search is inherently multisensory, in that the consumers' visual search for a specific brand can be facilitated by semantically related stimuli that are presented in another sensory modality. A series of 5 experiments demonstrates that the presentation of spatially nonpredictive auditory stimuli associated with products (e.g., usage sounds or product-related jingles) can crossmodally facilitate consumers' visual search for, and selection of, products. Eye-tracking data (Experiment 2) revealed that the crossmodal effect of auditory cues on visual search manifested itself not only in RTs, but also in the earliest stages of visual attentional processing, thus suggesting that the semantic information embedded within sounds can modulate the perceptual saliency of the target products' visual representations. Crossmodal facilitation was even observed for newly learnt associations between unfamiliar brands and sonic logos, implicating multisensory short-term learning in establishing audiovisual semantic associations. The facilitation effect was stronger when searching complex rather than simple visual displays, thus suggesting a modulatory role of perceptual load. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  18. Cannabis and psychosis: have we found the missing links?

    Science.gov (United States)

    Parakh, Preeti; Basu, Debasish

    2013-08-01

    The association between cannabis and psychosis has long been a matter of debate, with cannabis widely perceived as a harmless recreational drug. Electronic bibliographic databases like PubMed and Google Scholar were searched using the format "(psychosis or schizophrenia or synonyms) and (cannabis or synonyms)". Cross-linked searches were made taking the lead from key articles. Recent articles and those exploring the genetic factors or gene-environment interaction between cannabis use and psychosis were focussed upon. Heavy cannabis use at a n young age, in association with genetic liability to psychosis and exposure to environmental stressors like childhood trauma and urban upbringing increases the risk of psychotic outcome in later life. Cannabis acts as a component cause of psychosis, that is, it increases the risk of psychosis in people with certain genetic or environmental vulnerabilities, though by itself, it is neither a sufficient nor a necessary cause of psychosis. Although significant progress has been made over the last few years, we are yet to find all the missing links. Further work is necessary to identify all the factors that underlie individual vulnerability to cannabis-related psychosis and to elucidate the biological mechanisms underlying this risk. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. Contextual cueing of pop-out visual search: when context guides the deployment of attention.

    Science.gov (United States)

    Geyer, Thomas; Zehetleitner, Michael; Müller, Hermann J

    2010-05-01

    Visual context information can guide attention in demanding (i.e., inefficient) search tasks. When participants are repeatedly presented with identically arranged ('repeated') displays, reaction times are faster relative to newly composed ('non-repeated') displays. The present article examines whether this 'contextual cueing' effect operates also in simple (i.e., efficient) search tasks and if so, whether there it influences target, rather than response, selection. The results were that singleton-feature targets were detected faster when the search items were presented in repeated, rather than non-repeated, arrangements. Importantly, repeated, relative to novel, displays also led to an increase in signal detection accuracy. Thus, contextual cueing can expedite the selection of pop-out targets, most likely by enhancing feature contrast signals at the overall-salience computation stage.

  20. Controlled swollen and drug release from urea-cross-linked polyether/siloxane hybrids

    International Nuclear Information System (INIS)

    Santilli, Celso V.; Lopes, Leandro; Pulcinelli, Sandra H.; Chiavacci, Leila A.; Oliveira, Anselmo G.

    2009-01-01

    From a simple synthesis method we produced transparent ureasil cross-linked polyether (poly(ethylene oxide), PEO, or poly (propylene oxide), PPO) networks, whose designed inter cross-linking distance and tunable swell ability was assessed by small angle X-ray scattering on the D11A-SAXS1 beamline of the LNLS, we demonstrated that the controlled drug release from swell able hydrophilic ureasil-PEO materials can be sustained during some days, while from the unswell able ureasil-PPO ones, during some weeks. This outstanding feature conjugated with the bio medically safe formulation of the ureasil cross-linked polyether/siloxane hybrid widen their scope of application to include the domain of soft and implantable drug delivery devices. (author)

  1. An Active Damping Technique for Small DC-Link Capacitor Based Drive System

    DEFF Research Database (Denmark)

    Maheshwari, Ram Krishan; Munk-Nielsen, Stig; Lu, Kaiyuan

    2013-01-01

    A small dc-link capacitor based drive system shows instability when it is operated with large input line inductance at operating points with high power. This paper presents a simple, new active damping technique that can stabilize effectively the drive system at unstable operating points, offering...

  2. A search for symmetries in the genetic code

    International Nuclear Information System (INIS)

    Hornos, J.E.M.; Hornos, Y.M.M.

    1991-01-01

    A search for symmetries based on the classification theorem of Cartan for the compact simple Lie algebras is performed to verify to what extent the genetic code is a manifestation of some underlying symmetry. An exact continuous symmetry group cannot be found to reproduce the present, universal code. However a unique approximate symmetry group is compatible with codon assignment for the fundamental amino acids and the termination codon. In order to obtain the actual genetic code, the symmetry must be slightly broken. (author). 27 refs, 3 figs, 6 tabs

  3. A Web-based Tool for SDSS and 2MASS Database Searches

    Science.gov (United States)

    Hendrickson, M. A.; Uomoto, A.; Golimowski, D. A.

    We have developed a web site using HTML, Php, Python, and MySQL that extracts, processes, and displays data from the Sloan Digital Sky Survey (SDSS) and the Two-Micron All-Sky Survey (2MASS). The goal is to locate brown dwarf candidates in the SDSS database by looking at color cuts; however, this site could also be useful for targeted searches of other databases as well. MySQL databases are created from broad searches of SDSS and 2MASS data. Broad queries on the SDSS and 2MASS database servers are run weekly so that observers have the most up-to-date information from which to select candidates for observation. Observers can look at detailed information about specific objects including finding charts, images, and available spectra. In addition, updates from previous observations can be added by any collaborators; this format makes observational collaboration simple. Observers can also restrict the database search, just before or during an observing run, to select objects of special interest.

  4. Acceleration of saddle-point searches with machine learning

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, Andrew A., E-mail: andrew-peterson@brown.edu [School of Engineering, Brown University, Providence, Rhode Island 02912 (United States)

    2016-08-21

    In atomistic simulations, the location of the saddle point on the potential-energy surface (PES) gives important information on transitions between local minima, for example, via transition-state theory. However, the search for saddle points often involves hundreds or thousands of ab initio force calls, which are typically all done at full accuracy. This results in the vast majority of the computational effort being spent calculating the electronic structure of states not important to the researcher, and very little time performing the calculation of the saddle point state itself. In this work, we describe how machine learning (ML) can reduce the number of intermediate ab initio calculations needed to locate saddle points. Since machine-learning models can learn from, and thus mimic, atomistic simulations, the saddle-point search can be conducted rapidly in the machine-learning representation. The saddle-point prediction can then be verified by an ab initio calculation; if it is incorrect, this strategically has identified regions of the PES where the machine-learning representation has insufficient training data. When these training data are used to improve the machine-learning model, the estimates greatly improve. This approach can be systematized, and in two simple example problems we demonstrate a dramatic reduction in the number of ab initio force calls. We expect that this approach and future refinements will greatly accelerate searches for saddle points, as well as other searches on the potential energy surface, as machine-learning methods see greater adoption by the atomistics community.

  5. Acceleration of saddle-point searches with machine learning

    International Nuclear Information System (INIS)

    Peterson, Andrew A.

    2016-01-01

    In atomistic simulations, the location of the saddle point on the potential-energy surface (PES) gives important information on transitions between local minima, for example, via transition-state theory. However, the search for saddle points often involves hundreds or thousands of ab initio force calls, which are typically all done at full accuracy. This results in the vast majority of the computational effort being spent calculating the electronic structure of states not important to the researcher, and very little time performing the calculation of the saddle point state itself. In this work, we describe how machine learning (ML) can reduce the number of intermediate ab initio calculations needed to locate saddle points. Since machine-learning models can learn from, and thus mimic, atomistic simulations, the saddle-point search can be conducted rapidly in the machine-learning representation. The saddle-point prediction can then be verified by an ab initio calculation; if it is incorrect, this strategically has identified regions of the PES where the machine-learning representation has insufficient training data. When these training data are used to improve the machine-learning model, the estimates greatly improve. This approach can be systematized, and in two simple example problems we demonstrate a dramatic reduction in the number of ab initio force calls. We expect that this approach and future refinements will greatly accelerate searches for saddle points, as well as other searches on the potential energy surface, as machine-learning methods see greater adoption by the atomistics community.

  6. Acceleration of saddle-point searches with machine learning.

    Science.gov (United States)

    Peterson, Andrew A

    2016-08-21

    In atomistic simulations, the location of the saddle point on the potential-energy surface (PES) gives important information on transitions between local minima, for example, via transition-state theory. However, the search for saddle points often involves hundreds or thousands of ab initio force calls, which are typically all done at full accuracy. This results in the vast majority of the computational effort being spent calculating the electronic structure of states not important to the researcher, and very little time performing the calculation of the saddle point state itself. In this work, we describe how machine learning (ML) can reduce the number of intermediate ab initio calculations needed to locate saddle points. Since machine-learning models can learn from, and thus mimic, atomistic simulations, the saddle-point search can be conducted rapidly in the machine-learning representation. The saddle-point prediction can then be verified by an ab initio calculation; if it is incorrect, this strategically has identified regions of the PES where the machine-learning representation has insufficient training data. When these training data are used to improve the machine-learning model, the estimates greatly improve. This approach can be systematized, and in two simple example problems we demonstrate a dramatic reduction in the number of ab initio force calls. We expect that this approach and future refinements will greatly accelerate searches for saddle points, as well as other searches on the potential energy surface, as machine-learning methods see greater adoption by the atomistics community.

  7. Search Patterns

    CERN Document Server

    Morville, Peter

    2010-01-01

    What people are saying about Search Patterns "Search Patterns is a delight to read -- very thoughtful and thought provoking. It's the most comprehensive survey of designing effective search experiences I've seen." --Irene Au, Director of User Experience, Google "I love this book! Thanks to Peter and Jeffery, I now know that search (yes, boring old yucky who cares search) is one of the coolest ways around of looking at the world." --Dan Roam, author, The Back of the Napkin (Portfolio Hardcover) "Search Patterns is a playful guide to the practical concerns of search interface design. It cont

  8. Personalized Search

    CERN Document Server

    AUTHOR|(SzGeCERN)749939

    2015-01-01

    As the volume of electronically available information grows, relevant items become harder to find. This work presents an approach to personalizing search results in scientific publication databases. This work focuses on re-ranking search results from existing search engines like Solr or ElasticSearch. This work also includes the development of Obelix, a new recommendation system used to re-rank search results. The project was proposed and performed at CERN, using the scientific publications available on the CERN Document Server (CDS). This work experiments with re-ranking using offline and online evaluation of users and documents in CDS. The experiments conclude that the personalized search result outperform both latest first and word similarity in terms of click position in the search result for global search in CDS.

  9. Effects of multi-state links in network community detection

    International Nuclear Information System (INIS)

    Rocco, Claudio M.; Moronta, José; Ramirez-Marquez, José E.; Barker, Kash

    2017-01-01

    A community is defined as a group of nodes of a network that are densely interconnected with each other but only sparsely connected with the rest of the network. The set of communities (i.e., the network partition) and their inter-community links could be derived using special algorithms account for the topology of the network and, in certain cases, the possible weights associated to the links. In general, the set of weights represents some characteristic as capacity, flow and reliability, among others. The effects of considering weights could be translated to obtain a different partition. In many real situations, particularly when modeling infrastructure systems, networks must be modeled as multi-state networks (e.g., electric power networks). In such networks, each link is characterized by a vector of known random capacities (i.e., the weight on each link could vary according to a known probability distribution). In this paper a simple Monte Carlo approach is proposed to evaluate the effects of multi-state links on community detection as well as on the performance of the network. The approach is illustrated with the topology of an electric power system. - Highlights: • Identify network communities when considering multi-state links. • Identified how effects of considering weights translate to different partition. • Identified importance of Inter-Community Links and changes with respect to community. • Preamble to performing a resilience assessment able to mimic the evolution of the state of each community.

  10. Mastering Search Analytics Measuring SEO, SEM and Site Search

    CERN Document Server

    Chaters, Brent

    2011-01-01

    Many companies still approach Search Engine Optimization (SEO) and paid search as separate initiatives. This in-depth guide shows you how to use these programs as part of a comprehensive strategy-not just to improve your site's search rankings, but to attract the right people and increase your conversion rate. Learn how to measure, test, analyze, and interpret all of your search data with a wide array of analytic tools. Gain the knowledge you need to determine the strategy's return on investment. Ideal for search specialists, webmasters, and search marketing managers, Mastering Search Analyt

  11. Going where the ad leads you : On high advertised prices and searching where to buy

    NARCIS (Netherlands)

    Janssen, Maarten C. W.; Non, Marielle C.

    2009-01-01

    An important role of informative advertising is to inform consumers of the simple fact that the shop that advertises sells a particular product. This information may help consumers to save on their search activities: instead of wandering around, a consumer can simply visit the shop that has

  12. Enhancing network performance under single link failure with AS-disjoint BGP extension

    DEFF Research Database (Denmark)

    Manolova, Anna Vasileva; Romeral, S.; Ruepp, Sarah Renée

    2009-01-01

    In this paper we propose an enhancement of the BGP protocol for obtaining AS-disjoint paths in GMPLS multi-domain networks. We evaluate the benefits of having AS-disjoint paths under single inter-domain link failure for two main applications: routing of future connection requests during routing...... protocol re-convergence and applying multi-domain restoration as survivability mechanism in case of a single link failure. The proposed BGP modification is a simple and effective solution for disjoint path selection in connection-oriented multi-domain networks. Our results show that applying the proper...

  13. Multi-boundary entanglement in Chern-Simons theory and link invariants

    Energy Technology Data Exchange (ETDEWEB)

    Balasubramanian, Vijay [David Rittenhouse Laboratory, University of Pennsylvania,209 S.33rd Street, Philadelphia, PA 19104 (United States); Theoretische Natuurkunde, Vrije Universiteit Brussel (VUB) andInternational Solvay Institutes,Pleinlaan 2, B-1050 Brussels (Belgium); Fliss, Jackson R.; Leigh, Robert G. [Department of Physics, University of Illinois,1110 W. Green Street, Urbana, IL 61801 (United States); Parrikar, Onkar [David Rittenhouse Laboratory, University of Pennsylvania,209 S.33rd Street, Philadelphia, PA 19104 (United States)

    2017-04-11

    We consider Chern-Simons theory for gauge group G at level k on 3-manifolds M{sub n} with boundary consisting of n topologically linked tori. The Euclidean path integral on M{sub n} defines a quantum state on the boundary, in the n-fold tensor product of the torus Hilbert space. We focus on the case where M{sub n} is the link-complement of some n-component link inside the three-sphere S{sup 3}. The entanglement entropies of the resulting states define framing-independent link invariants which are sensitive to the topology of the chosen link. For the Abelian theory at level k (G=U(1){sub k}) we give a general formula for the entanglement entropy associated to an arbitrary (m|n−m) partition of a generic n-component link into sub-links. The formula involves the number of solutions to certain Diophantine equations with coefficients related to the Gauss linking numbers (mod k) between the two sublinks. This formula connects simple concepts in quantum information theory, knot theory, and number theory, and shows that entanglement entropy between sublinks vanishes if and only if they have zero Gauss linking (mod k). For G=SU(2){sub k}, we study various two and three component links. We show that the 2-component Hopf link is maximally entangled, and hence analogous to a Bell pair, and that the Whitehead link, which has zero Gauss linking, nevertheless has entanglement entropy. Finally, we show that the Borromean rings have a “W-like' entanglement structure (i.e., tracing out one torus does not lead to a separable state), and give examples of other 3-component links which have “GHZ-like” entanglement (i.e., tracing out one torus does lead to a separable state).

  14. Simple Kidney Cysts

    Science.gov (United States)

    ... Solitary Kidney Your Kidneys & How They Work Simple Kidney Cysts What are simple kidney cysts? Simple kidney cysts are abnormal, fluid-filled ... that form in the kidneys. What are the kidneys and what do they do? The kidneys are ...

  15. e+e- interactions at very high energy: searching beyond the standard model

    International Nuclear Information System (INIS)

    Dorfan, J.

    1983-04-01

    These lectures discuss e + e - interactions at very high energies with a particular emphasis on searching the standard model which we take to be SU(3)/sub color/Λ SU(2) Λ U(1). The highest e + e - collision energy exploited to date is at PETRA where data have been taken at 38 GeV. We will consider energies above this to be the very high energy frontier. The lectures will begin with a review of the collision energies which will be available in the upgraded machines of today and the machines planned for tomorrow. Without going into great detail, we will define the essential elements of the standard model. We will remind ourselves that some of these essential elements have not yet been verified and that part of the task of searching beyond the standard model will involve experiments aimed at this verification. For if we find the standard model lacking, then clearly we are forced to find an alternative. So we will investigate how the higher energy e + e - collisions can be used to search for the top quark, the neutral Higgs scalar, provide true verification of the non-Abelian nature of QCD, etc. Having done this we will look at tests of models involving simple extensions of the standard model. Models considered are those without a top quark, those with charged Higgs scalars, with multiple and/or composite vector bosons, with additional generations and possible alternative explanations for the PETRA three jet events which don't require gluon bremsstrahlung. From the simple extensions of the standard model we will move to more radical alternatives, alternatives which have arisen from the unhappiness with the gauge hierarchy problem of the standard model. Technicolor, Supersymmetry and composite models will be discussed. In the final section we will summarize what the future holds in terms of the search beyond the standard model

  16. A cultural take on the links between religiosity, identity, and meaning in life in religious emerging adults.

    Science.gov (United States)

    Negru-Subtirica, Oana; Tiganasu, Alexandra; Dezutter, Jessie; Luyckx, Koen

    2017-03-01

    Identity and meaning in life are core developmental assets in emerging adulthood. We analysed how religiosity is related to these intentional strivings in emerging adults enrolled in theological education, by depicting (1) identity strivings and meaning in life accounts in faith narratives (Study 1) and (2) links between personal identity and meaning in life profiles and religious beliefs, behaviours, and subjective experiences (Study 2). Both studies highlighted that a Foreclosed status, with high personal commitment and reduced exploration, was dominant in faith narratives and personal identity profiles. Also, in narratives meaning in life was reflected by a strong focus on presence of meaning through religious insights. Nonetheless, global meaning in life profiles indicated that many emerging adults were searching for a meaning in their lives, while reporting lower levels of presence of meaning. Identity Achievement and High Presence-High Search profiles were linked to the highest levels of subjective, behavioural, and cognitive religiosity. We highlighted the multidimensionality of identity and meaning in life strivings in emerging adults attending theological schools. We pointed out that even in a somewhat foreclosed cultural context (e.g., Romanian Christian Orthodox theological schools), religion represents a dynamic social and ideological context for self-development. Statement of contribution What is already known on this subject? Religious beliefs increase in emerging adults, doubled by decreases in religious behaviours, linked to an adherence to a more personal approach to religion. Religious youth are more committed to their faith and also explore identity and life meaning in relation to their religious strivings. Youth religious exemplars report close links between their religious faith and strivings for meaningful life goals. What does this study add? We investigated Christian Orthodox theology students, for whom religion is a normative dimension of

  17. R dump converter without DC link capacitor for an 8/6 SRM: experimental investigation.

    Science.gov (United States)

    Kavitha, Pasumalaithevan; Umamaheswari, Bhaskaran

    2015-01-01

    The objective of this paper is to investigate the performance of 8/6 switched reluctance motor (SRM) when excited with sinusoidal voltage. The conventional R dump converter provides DC excitation with the help of capacitor. In this paper the converter used is the modified R dump converter without DC link capacitor providing AC or sinusoidal excitation. Torque ripple and speed ripple are investigated based on hysteresis current control. Constant and sinusoidal current references are considered for comparison in both DC and AC excitation. Extensive theoretical and experimental investigations are made to bring out the merits and demerits of AC versus DC excitation. It is shown that the constructionally simple SRM can be favorably controlled with simple R dump converter with direct AC excitation without need for DC link capacitor. A 4-phase 8/6 0.5 kW SRM is used for experimentation.

  18. Retrospective group fusion similarity search based on eROCE evaluation metric.

    Science.gov (United States)

    Avram, Sorin I; Crisan, Luminita; Bora, Alina; Pacureanu, Liliana M; Avram, Stefana; Kurunczi, Ludovic

    2013-03-01

    In this study, a simple evaluation metric, denoted as eROCE was proposed to measure the early enrichment of predictive methods. We demonstrated the superior robustness of eROCE compared to other known metrics throughout several active to inactive ratios ranging from 1:10 to 1:1000. Group fusion similarity search was investigated by varying 16 similarity coefficients, five molecular representations (binary and non-binary) and two group fusion rules using two reference structure set sizes. We used a dataset of 3478 actives and 43,938 inactive molecules and the enrichment was analyzed by means of eROCE. This retrospective study provides optimal similarity search parameters in the case of ALDH1A1 inhibitors. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Search Help

    Science.gov (United States)

    Guidance and search help resource listing examples of common queries that can be used in the Google Search Appliance search request, including examples of special characters, or query term seperators that Google Search Appliance recognizes.

  20. Extended-Search, Bézier Curve-Based Lane Detection and Reconstruction System for an Intelligent Vehicle

    Directory of Open Access Journals (Sweden)

    Xiaoyun Huang

    2015-09-01

    Full Text Available To improve the real-time performance and detection rate of a Lane Detection and Reconstruction (LDR system, an extended-search-based lane detection method and a Bézier curve-based lane reconstruction algorithm are proposed in this paper. The extended-search-based lane detection method is designed to search boundary blocks from the initial position, in an upwards direction and along the lane, with small search areas including continuous search, discontinuous search and bending search in order to detect different lane boundaries. The Bézier curve-based lane reconstruction algorithm is employed to describe a wide range of lane boundary forms with comparatively simple expressions. In addition, two Bézier curves are adopted to reconstruct the lanes' outer boundaries with large curvature variation. The lane detection and reconstruction algorithm — including initial-blocks' determining, extended search, binarization processing and lane boundaries' fitting in different scenarios — is verified in road tests. The results show that this algorithm is robust against different shadows and illumination variations; the average processing time per frame is 13 ms. Significantly, it presents an 88.6% high-detection rate on curved lanes with large or variable curvatures, where the accident rate is higher than that of straight lanes.

  1. Random blebbing motion: A simple model linking cell structural properties to migration characteristics

    Science.gov (United States)

    Woolley, Thomas E.; Gaffney, Eamonn A.; Goriely, Alain

    2017-07-01

    If the plasma membrane of a cell is able to delaminate locally from its actin cortex, a cellular bleb can be produced. Blebs are pressure-driven protrusions, which are noteworthy for their ability to produce cellular motion. Starting from a general continuum mechanics description, we restrict ourselves to considering cell and bleb shapes that maintain approximately spherical forms. From this assumption, we obtain a tractable algebraic system for bleb formation. By including cell-substrate adhesions, we can model blebbing cell motility. Further, by considering mechanically isolated blebbing events, which are randomly distributed over the cell, we can derive equations linking the macroscopic migration characteristics to the microscopic structural parameters of the cell. This multiscale modeling framework is then used to provide parameter estimates, which are in agreement with current experimental data. In summary, the construction of the mathematical model provides testable relationships between the bleb size and cell motility.

  2. Random blebbing motion: A simple model linking cell structural properties to migration characteristics.

    Science.gov (United States)

    Woolley, Thomas E; Gaffney, Eamonn A; Goriely, Alain

    2017-07-01

    If the plasma membrane of a cell is able to delaminate locally from its actin cortex, a cellular bleb can be produced. Blebs are pressure-driven protrusions, which are noteworthy for their ability to produce cellular motion. Starting from a general continuum mechanics description, we restrict ourselves to considering cell and bleb shapes that maintain approximately spherical forms. From this assumption, we obtain a tractable algebraic system for bleb formation. By including cell-substrate adhesions, we can model blebbing cell motility. Further, by considering mechanically isolated blebbing events, which are randomly distributed over the cell, we can derive equations linking the macroscopic migration characteristics to the microscopic structural parameters of the cell. This multiscale modeling framework is then used to provide parameter estimates, which are in agreement with current experimental data. In summary, the construction of the mathematical model provides testable relationships between the bleb size and cell motility.

  3. Use of AFIS for linking scenes of crime.

    Science.gov (United States)

    Hefetz, Ido; Liptz, Yakir; Vaturi, Shaul; Attias, David

    2016-05-01

    Forensic intelligence can provide critical information in criminal investigations - the linkage of crime scenes. The Automatic Fingerprint Identification System (AFIS) is an example of a technological improvement that has advanced the entire forensic identification field to strive for new goals and achievements. In one example using AFIS, a series of burglaries into private apartments enabled a fingerprint examiner to search latent prints from different burglary scenes against an unsolved latent print database. Latent finger and palm prints coming from the same source were associated with over than 20 cases. Then, by forensic intelligence and profile analysis the offender's behavior could be anticipated. He was caught, identified, and arrested. It is recommended to perform an AFIS search of LT/UL prints against current crimes automatically as part of laboratory protocol and not by an examiner's discretion. This approach may link different crime scenes. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Mortality estimation from carcass searches using the R-package carcass: a tutorial

    Science.gov (United States)

    Korner-Nievergelt, Fränzi; Behr, Oliver; Brinkmann, Robert; Etterson, Matthew A.; Huso, Manuela M. P.; Dalthorp, Daniel; Korner-Nievergelt, Pius; Roth, Tobias; Niermann, Ivo

    2015-01-01

    This article is a tutorial for the R-package carcass. It starts with a short overview of common methods used to estimate mortality based on carcass searches. Then, it guides step by step through a simple example. First, the proportion of animals that fall into the search area is estimated. Second, carcass persistence time is estimated based on experimental data. Third, searcher efficiency is estimated. Fourth, these three estimated parameters are combined to obtain the probability that an animal killed is found by an observer. Finally, this probability is used together with the observed number of carcasses found to obtain an estimate for the total number of killed animals together with a credible interval.

  5. Tales from the Field: Search Strategies Applied in Web Searching

    Directory of Open Access Journals (Sweden)

    Soohyung Joo

    2010-08-01

    Full Text Available In their web search processes users apply multiple types of search strategies, which consist of different search tactics. This paper identifies eight types of information search strategies with associated cases based on sequences of search tactics during the information search process. Thirty-one participants representing the general public were recruited for this study. Search logs and verbal protocols offered rich data for the identification of different types of search strategies. Based on the findings, the authors further discuss how to enhance web-based information retrieval (IR systems to support each type of search strategy.

  6. Phosphoric acid doped polysulfone membranes with aminopyridine pendant groups and imidazole cross-links

    DEFF Research Database (Denmark)

    Hink, Steffen; Elsøe, Katrine; Cleemann, Lars Nilausen

    2015-01-01

    Udel polysulfone based membranes with 4-aminopyridine pendant groups and cross-linking imidazole units are synthesized in a simple two step reaction. The ratio of 4-aminopyridine and imidazole is varied and the materials are extensively characterized. The average phosphoric acid uptake (in 85 wt%...

  7. Partial Transmit Sequence Optimization Using Improved Harmony Search Algorithm for PAPR Reduction in OFDM

    Directory of Open Access Journals (Sweden)

    Mangal Singh

    2017-12-01

    Full Text Available This paper considers the use of the Partial Transmit Sequence (PTS technique to reduce the Peak‐to‐Average Power Ratio (PAPR of an Orthogonal Frequency Division Multiplexing signal in wireless communication systems. Search complexity is very high in the traditional PTS scheme because it involves an extensive random search over all combinations of allowed phase vectors, and it increases exponentially with the number of phase vectors. In this paper, a suboptimal metaheuristic algorithm for phase optimization based on an improved harmony search (IHS is applied to explore the optimal combination of phase vectors that provides improved performance compared with existing evolutionary algorithms such as the harmony search algorithm and firefly algorithm. IHS enhances the accuracy and convergence rate of the conventional algorithms with very few parameters to adjust. Simulation results show that an improved harmony search‐based PTS algorithm can achieve a significant reduction in PAPR using a simple network structure compared with conventional algorithms.

  8. Internet Search Engines

    OpenAIRE

    Fatmaa El Zahraa Mohamed Abdou

    2004-01-01

    A general study about the internet search engines, the study deals main 7 points; the differance between search engines and search directories, components of search engines, the percentage of sites covered by search engines, cataloging of sites, the needed time for sites appearance in search engines, search capabilities, and types of search engines.

  9. The Top 100 Linked-To Pages on UK University Web Sites: High Inlink Counts Are Not Usually Associated with Quality Scholarly Content.

    Science.gov (United States)

    Thelwall, Mike

    2002-01-01

    Reports on an investigation into the most highly linked pages on United Kingdom university Web sites. Concludes that simple link counts are highly unreliable indicators of the average behavior of scholars, and that the most highly linked-to pages are those that facilitate access to a wide range of information rather than providing specific…

  10. University Students' Online Information Searching Strategies in Different Search Contexts

    Science.gov (United States)

    Tsai, Meng-Jung; Liang, Jyh-Chong; Hou, Huei-Tse; Tsai, Chin-Chung

    2012-01-01

    This study investigates the role of search context played in university students' online information searching strategies. A total of 304 university students in Taiwan were surveyed with questionnaires in which two search contexts were defined as searching for learning, and searching for daily life information. Students' online search strategies…

  11. Obstacle Avoidance for Redundant Manipulators Utilizing a Backward Quadratic Search Algorithm

    Directory of Open Access Journals (Sweden)

    Tianjian Hu

    2016-06-01

    Full Text Available Obstacle avoidance can be achieved as a secondary task by appropriate inverse kinematics (IK resolution of redundant manipulators. Most prior literature requires the time-consuming determination of the closest point to the obstacle for every calculation step. Aiming at the relief of computational burden, this paper develops what is termed a backward quadratic search algorithm (BQSA as another option for solving IK problems in obstacle avoidance. The BQSA detects possible collisions based on the root property of a category of quadratic functions, which are derived from ellipse-enveloped obstacles and the positions of each link's end-points. The algorithm executes a backward search for possible obstacle collisions, from the end-effector to the base, and avoids obstacles by utilizing a hybrid IK scheme, incorporating the damped least-squares method, the weighted least-norm method and the gradient projection method. Some details of the hybrid IK scheme, such as values of the damped factor, weights and the clamping velocity, are discussed, along with a comparison of computational load between previous methods and BQSA. Simulations of a planar seven-link manipulator and a PUMA 560 robot verify the effectiveness of BQSA.

  12. A simple dynamic energy capacity model

    International Nuclear Information System (INIS)

    Gander, James P.

    2012-01-01

    I develop a simple dynamic model showing how total energy capacity is allocated to two different uses and how these uses and their corresponding energy flows are related and behave through time. The control variable of the model determines the allocation. All the variables of the model are in terms of a composite energy equivalent measured in BTU's. A key focus is on the shadow price of energy capacity and its behavior through time. Another key focus is on the behavior of the control variable that determines the allocation of overall energy capacity. The matching or linking of the model's variables to real world U.S. energy data is undertaken. In spite of some limitations of the data, the model and its behavior fit the data fairly well. Some energy policy implications are discussed. - Highlights: ► The model shows how energy capacity is allocated to current output production versus added energy capacity production. ► Two variables in the allocation are the shadow price of capacity and the control variable that determines the allocation. ► The model was linked to U.S. historical energy data and fit the data quite well. ► In particular, the policy control variable was cyclical and consistent with the model. ► Policy implications relevant to the allocation of energy capacity are discussed briefly.

  13. The topography of the environment alters the optimal search strategy for active particles

    Science.gov (United States)

    Volpe, Giorgio; Volpe, Giovanni

    2017-10-01

    In environments with scarce resources, adopting the right search strategy can make the difference between succeeding and failing, even between life and death. At different scales, this applies to molecular encounters in the cell cytoplasm, to animals looking for food or mates in natural landscapes, to rescuers during search and rescue operations in disaster zones, and to genetic computer algorithms exploring parameter spaces. When looking for sparse targets in a homogeneous environment, a combination of ballistic and diffusive steps is considered optimal; in particular, more ballistic Lévy flights with exponent α≤1 are generally believed to optimize the search process. However, most search spaces present complex topographies. What is the best search strategy in these more realistic scenarios? Here, we show that the topography of the environment significantly alters the optimal search strategy toward less ballistic and more Brownian strategies. We consider an active particle performing a blind cruise search for nonregenerating sparse targets in a 2D space with steps drawn from a Lévy distribution with the exponent varying from α=1 to α=2 (Brownian). We show that, when boundaries, barriers, and obstacles are present, the optimal search strategy depends on the topography of the environment, with α assuming intermediate values in the whole range under consideration. We interpret these findings using simple scaling arguments and discuss their robustness to varying searcher's size. Our results are relevant for search problems at different length scales from animal and human foraging to microswimmers' taxis to biochemical rates of reaction.

  14. Reinforcement of Smoking and Drinking: Tobacco Marketing Strategies Linked With Alcohol in the United States

    Science.gov (United States)

    Jiang, Nan

    2011-01-01

    Objectives. We investigated tobacco companies’ knowledge about concurrent use of tobacco and alcohol, their marketing strategies linking cigarettes with alcohol, and the benefits tobacco companies sought from these marketing activities. Methods. We performed systematic searches on previously secret tobacco industry documents, and we summarized the themes and contexts of relevant search results. Results. Tobacco company research confirmed the association between tobacco use and alcohol use. Tobacco companies explored promotional strategies linking cigarettes and alcohol, such as jointly sponsoring special events with alcohol companies to lower the cost of sponsorships, increase consumer appeal, reinforce brand identity, and generate increased cigarette sales. They also pursued promotions that tied cigarette sales to alcohol purchases, and cigarette promotional events frequently featured alcohol discounts or encouraged alcohol use. Conclusions. Tobacco companies’ numerous marketing strategies linking cigarettes with alcohol may have reinforced the use of both substances. Because using tobacco and alcohol together makes it harder to quit smoking, policies prohibiting tobacco sales and promotion in establishments where alcohol is served and sold might mitigate this effect. Smoking cessation programs should address the effect that alcohol consumption has on tobacco use. PMID:21852637

  15. Trophic dynamics of a simple model ecosystem.

    Science.gov (United States)

    Bell, Graham; Fortier-Dubois, Étienne

    2017-09-13

    We have constructed a model of community dynamics that is simple enough to enumerate all possible food webs, yet complex enough to represent a wide range of ecological processes. We use the transition matrix to predict the outcome of succession and then investigate how the transition probabilities are governed by resource supply and immigration. Low-input regimes lead to simple communities whereas trophically complex communities develop when there is an adequate supply of both resources and immigrants. Our interpretation of trophic dynamics in complex communities hinges on a new principle of mutual replenishment, defined as the reciprocal alternation of state in a pair of communities linked by the invasion and extinction of a shared species. Such neutral couples are the outcome of succession under local dispersal and imply that food webs will often be made up of suites of trophically equivalent species. When immigrants arrive from an external pool of fixed composition a similar principle predicts a dynamic core of webs constituting a neutral interchange network, although communities may express an extensive range of other webs whose membership is only in part predictable. The food web is not in general predictable from whole-community properties such as productivity or stability, although it may profoundly influence these properties. © 2017 The Author(s).

  16. Fast parallel tandem mass spectral library searching using GPU hardware acceleration.

    Science.gov (United States)

    Baumgardner, Lydia Ashleigh; Shanmugam, Avinash Kumar; Lam, Henry; Eng, Jimmy K; Martin, Daniel B

    2011-06-03

    Mass spectrometry-based proteomics is a maturing discipline of biologic research that is experiencing substantial growth. Instrumentation has steadily improved over time with the advent of faster and more sensitive instruments collecting ever larger data files. Consequently, the computational process of matching a peptide fragmentation pattern to its sequence, traditionally accomplished by sequence database searching and more recently also by spectral library searching, has become a bottleneck in many mass spectrometry experiments. In both of these methods, the main rate-limiting step is the comparison of an acquired spectrum with all potential matches from a spectral library or sequence database. This is a highly parallelizable process because the core computational element can be represented as a simple but arithmetically intense multiplication of two vectors. In this paper, we present a proof of concept project taking advantage of the massively parallel computing available on graphics processing units (GPUs) to distribute and accelerate the process of spectral assignment using spectral library searching. This program, which we have named FastPaSS (for Fast Parallelized Spectral Searching), is implemented in CUDA (Compute Unified Device Architecture) from NVIDIA, which allows direct access to the processors in an NVIDIA GPU. Our efforts demonstrate the feasibility of GPU computing for spectral assignment, through implementation of the validated spectral searching algorithm SpectraST in the CUDA environment.

  17. The sources and popularity of online drug information: an analysis of top search engine results and web page views.

    Science.gov (United States)

    Law, Michael R; Mintzes, Barbara; Morgan, Steven G

    2011-03-01

    The Internet has become a popular source of health information. However, there is little information on what drug information and which Web sites are being searched. To investigate the sources of online information about prescription drugs by assessing the most common Web sites returned in online drug searches and to assess the comparative popularity of Web pages for particular drugs. This was a cross-sectional study of search results for the most commonly dispensed drugs in the US (n=278 active ingredients) on 4 popular search engines: Bing, Google (both US and Canada), and Yahoo. We determined the number of times a Web site appeared as the first result. A linked retrospective analysis counted Wikipedia page hits for each of these drugs in 2008 and 2009. About three quarters of the first result on Google USA for both brand and generic names linked to the National Library of Medicine. In contrast, Wikipedia was the first result for approximately 80% of generic name searches on the other 3 sites. On these other sites, over two thirds of brand name searches led to industry-sponsored sites. The Wikipedia pages with the highest number of hits were mainly for opiates, benzodiazepines, antibiotics, and antidepressants. Wikipedia and the National Library of Medicine rank highly in online drug searches. Further, our results suggest that patients most often seek information on drugs with the potential for dependence, for stigmatized conditions, that have received media attention, and for episodic treatments. Quality improvement efforts should focus on these drugs.

  18. Quasispecies made simple.

    Directory of Open Access Journals (Sweden)

    2005-11-01

    Full Text Available Quasispecies are clouds of genotypes that appear in a population at mutation-selection balance. This concept has recently attracted the attention of virologists, because many RNA viruses appear to generate high levels of genetic variation that may enhance the evolution of drug resistance and immune escape. The literature on these important evolutionary processes is, however, quite challenging. Here we use simple models to link mutation-selection balance theory to the most novel property of quasispecies: the error threshold-a mutation rate below which populations equilibrate in a traditional mutation-selection balance and above which the population experiences an error catastrophe, that is, the loss of the favored genotype through frequent deleterious mutations. These models show that a single fitness landscape may contain multiple, hierarchically organized error thresholds and that an error threshold is affected by the extent of back mutation and redundancy in the genotype-to-phenotype map. Importantly, an error threshold is distinct from an extinction threshold, which is the complete loss of the population through lethal mutations. Based on this framework, we argue that the lethal mutagenesis of a viral infection by mutation-inducing drugs is not a true error catastophe, but is an extinction catastrophe.

  19. Event displays and plots of latest results from ATLAS Higgs Search

    CERN Multimedia

    ATLAS, collaboration

    2012-01-01

    On 4 July, 2012, the ATLAS experiment presented a preview of its updated results on the search for the Higgs Boson. The results were shown at a seminar held jointly at CERN and via video link at ICHEP 2012, the International Conference for High Energy Physics in Melbourne, Australia, where detailed analyses will be presented later this week. More information at http://atlas.cern

  20. Is simple nephrectomy truly simple? Comparison with the radical alternative.

    Science.gov (United States)

    Connolly, S S; O'Brien, M Frank; Kunni, I M; Phelan, E; Conroy, R; Thornhill, J A; Grainger, R

    2011-03-01

    The Oxford English dictionary defines the term "simple" as "easily done" and "uncomplicated". We tested the validity of this terminology in relation to open nephrectomy surgery. Retrospective review of 215 patients undergoing open, simple (n = 89) or radical (n = 126) nephrectomy in a single university-affiliated institution between 1998 and 2002. Operative time (OT), estimated blood loss (EBL), operative complications (OC) and length of stay in hospital (LOS) were analysed. Statistical analysis employed Fisher's exact test and Stata Release 8.2. Simple nephrectomy was associated with shorter OT (mean 126 vs. 144 min; p = 0.002), reduced EBL (mean 729 vs. 859 cc; p = 0.472), lower OC (9 vs. 17%; 0.087), and more brief LOS (mean 6 vs. 8 days; p < 0.001). All parameters suggest favourable outcome for the simple nephrectomy group, supporting the use of this terminology. This implies "simple" nephrectomies are truly easier to perform with less complication than their radical counterpart.

  1. INTERFACING GOOGLE SEARCH ENGINE TO CAPTURE USER WEB SEARCH BEHAVIOR

    OpenAIRE

    Fadhilah Mat Yamin; T. Ramayah

    2013-01-01

    The behaviour of the searcher when using the search engine especially during the query formulation is crucial. Search engines capture users’ activities in the search log, which is stored at the search engine server. Due to the difficulty of obtaining this search log, this paper proposed and develops an interface framework to interface a Google search engine. This interface will capture users’ queries before redirect them to Google. The analysis of the search log will show that users are utili...

  2. A Unified Performance Analysis of Free-Space Optical Links over Gamma-Gamma Turbulence Channels with Pointing Errors

    KAUST Repository

    Ansari, Imran Shafique

    2013-11-13

    In this work, we present a unified performance analysis of a free-space optical (FSO) link that accounts for pointing errors and both types of detection techniques (i.e. intensity modulation/direct detection as well as heterodyne detection). More specifically, we present unified exact closed-form expressions for the cumulative distribution function, the probability density function, the moment generating function, and the moments of the end-to-end signal-to-noise ratio (SNR) of a single link FSO transmission system, all in terms of the Meijer\\'s G function except for the moments that is in terms of simple elementary functions. We then capitalize on these unified results to offer unified exact closed-form expressions for various performance metrics of FSO link transmission systems, such as, the outage probability, the higher-order amount of fading (AF), the average error rate for binary and M-ary modulation schemes, and the ergodic capacity, all in terms of Meijer\\'s G functions except for the higher-order AF that is in terms of simple elementary functions. Additionally, we derive the asymptotic results for all the expressions derived earlier in terms of Meijer\\'s G function in the high SNR regime in terms of simple elementary functions via an asymptotic expansion of the Meijer\\'s G function. We also derive new asymptotic expressions for the ergodic capacity in the low as well as high SNR regimes in terms of simple elementary functions via utilizing moments. All the presented results are verified via computer-based Monte-Carlo simulations.

  3. Can Google Searches Predict the Popularity and Harm of Psychoactive Agents?

    Science.gov (United States)

    Jankowski, Wojciech; Hoffmann, Marcin

    2016-02-25

    Predicting the popularity of and harm caused by psychoactive agents is a serious problem that would be difficult to do by a single simple method. However, because of the growing number of drugs it is very important to provide a simple and fast tool for predicting some characteristics of these substances. We were inspired by the Google Flu Trends study on the activity of the influenza virus, which showed that influenza virus activity worldwide can be monitored based on queries entered into the Google search engine. Our aim was to propose a fast method for ranking the most popular and most harmful drugs based on easily available data gathered from the Internet. We used the Google search engine to acquire data for the ranking lists. Subsequently, using the resulting list and the frequency of hits for the respective psychoactive drugs combined with the word "harm" or "harmful", we estimated quickly how much harm is associated with each drug. We ranked the most popular and harmful psychoactive drugs. As we conducted the research over a period of several months, we noted that the relative popularity indexes tended to change depending on when we obtained them. This suggests that the data may be useful in monitoring changes over time in the use of each of these psychoactive agents. Our data correlate well with the results from a multicriteria decision analysis of drug harms in the United Kingdom. We showed that Google search data can be a valuable source of information to assess the popularity of and harm caused by psychoactive agents and may help in monitoring drug use trends.

  4. [Advanced online search techniques and dedicated search engines for physicians].

    Science.gov (United States)

    Nahum, Yoav

    2008-02-01

    In recent years search engines have become an essential tool in the work of physicians. This article will review advanced search techniques from the world of information specialists, as well as some advanced search engine operators that may help physicians improve their online search capabilities, and maximize the yield of their searches. This article also reviews popular dedicated scientific and biomedical literature search engines.

  5. Heuristics for Relevancy Ranking of Earth Dataset Search Results

    Science.gov (United States)

    Lynnes, Christopher; Quinn, Patrick; Norton, James

    2016-01-01

    As the Variety of Earth science datasets increases, science researchers find it more challenging to discover and select the datasets that best fit their needs. The most common way of search providers to address this problem is to rank the datasets returned for a query by their likely relevance to the user. Large web page search engines typically use text matching supplemented with reverse link counts, semantic annotations and user intent modeling. However, this produces uneven results when applied to dataset metadata records simply externalized as a web page. Fortunately, data and search provides have decades of experience in serving data user communities, allowing them to form heuristics that leverage the structure in the metadata together with knowledge about the user community. Some of these heuristics include specific ways of matching the user input to the essential measurements in the dataset and determining overlaps of time range and spatial areas. Heuristics based on the novelty of the datasets can prioritize later, better versions of data over similar predecessors. And knowledge of how different user types and communities use data can be brought to bear in cases where characteristics of the user (discipline, expertise) or their intent (applications, research) can be divined. The Earth Observing System Data and Information System has begun implementing some of these heuristics in the relevancy algorithm of its Common Metadata Repository search engine.

  6. Simple webs of natural environment theme as a result of sharing in science teacher training

    Science.gov (United States)

    Tapilouw, M. C.; Firman, H.; Redjeki, S.; Chandra, D. T.

    2018-03-01

    Thematic learning is one type of integrated science (Biology, Physics, Chemistry and Earth Science) in Science Education. This study is concerning about simple webs of natural environment theme in science learning, as one of training material in science teacher training program. Making simple web is a goal of first step in teacher training program. Every group explain their web illustration to other group. Twenty Junior High School science teacher above one education foundation participate in science teacher training program. In order to gather simple webs, sharing method was used in this first step of science teacher training. The result of this study is five different simple web of natural environment themes. These webs represent science learning in class VII/Semester I, class VII/Semester II, Class VIII, Class IX/Semester I, Class IX/Semester II based on basic competency in National Curriculum 2013. Each group discussed web of natural environment theme based on their learning experience in real class which basic competency and subject matters are linked with natural environment theme. As a conclusion, simple webs are potential to develop in the next step of science teacher training program and to be implemented in real class.

  7. a simple a simple excitation control excitation control excitation

    African Journals Online (AJOL)

    eobe

    field voltages determined follow a simple quadratic relationship that offer a very simple control scheme, dependent on only the stator current. Keywords: saturated reactances, no-load field voltage, excitation control, synchronous generators. 1. Introduction. Introduction. Introduction. The commonest generator in use today is ...

  8. The Antibiotic Resistance ‘Mobilome’: searching for the link between environment and clinic.

    Directory of Open Access Journals (Sweden)

    Julie ePerry

    2013-05-01

    Full Text Available Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia. The environmental ‘resistome’ is the collection of all genes that directly or indirectly contribute to antibiotic resistance. Many of these resistance determinants originate in antibiotic-producing organisms (where they serve to mediate self-immunity, while others become resistance determinants only when mobilized and over-expressed in non-native hosts (like plasmid-based β-lactamases. The modern environmental resistome is under selective pressure from human activities such as agriculture, which may influence the composition of the local resistome and lead to gene transfer events. Beyond the environment, we are challenged in the clinic by the rise in both frequency and diversity of antibiotic resistant pathogens. We assume that clinical resistance originated in the environment, but few examples of direct gene exchange between the environmental resistome and the clinical resistome have been documented. Strong evidence exists to suggest that clinical aminoglycoside and vancomycin resistance enzymes, the extended-spectrum β-lactamase CTX-M and the quinolone resistance gene Qnr have direct links to the environmental resistome. In this review, we highlight recent advances in our understanding of horizontal gene transfer of antibiotic resistance genes from the environment to the clinic. Improvements in sequencing technologies coupled with functional metagenomic studies have revealed previously underappreciated diversity in the environmental resistome, and also established novel genetic links to the clinic. Understanding mechanisms of gene exchange becomes vital in controlling the future dissemination of antibiotic resistance.

  9. The antibiotic resistance “mobilome”: searching for the link between environment and clinic

    Science.gov (United States)

    Perry, Julie A.; Wright, Gerard D.

    2013-01-01

    Antibiotic resistance is an ancient problem, owing to the co-evolution of antibiotic-producing and target organisms in the soil and other environments over millennia. The environmental “resistome” is the collection of all genes that directly or indirectly contribute to antibiotic resistance. Many of these resistance determinants originate in antibiotic-producing organisms (where they serve to mediate self-immunity), while others become resistance determinants only when mobilized and over-expressed in non-native hosts (like plasmid-encoded β-lactamases). The modern environmental resistome is under selective pressure from human activities such as agriculture, which may influence the composition of the local resistome and lead to gene transfer events. Beyond the environment, we are challenged in the clinic by the rise in both frequency and diversity of antibiotic resistant pathogens. We assume that clinical resistance originated in the environment, but few examples of direct gene exchange between the environmental resistome and the clinical resistome have been documented. Strong evidence exists to suggest that clinical aminoglycoside and vancomycin resistance enzymes, the extended-spectrum β-lactamase CTX-M and the quinolone resistance gene qnr have direct links to the environmental resistome. In this review, we highlight recent advances in our understanding of horizontal gene transfer of antibiotic resistance genes from the environment to the clinic. Improvements in sequencing technologies coupled with functional metagenomic studies have revealed previously underappreciated diversity in the environmental resistome, and also established novel genetic links to the clinic. Understanding mechanisms of gene exchange becomes vital in controlling the future dissemination of antibiotic resistance. PMID:23755047

  10. Children's Search Engines from an Information Search Process Perspective.

    Science.gov (United States)

    Broch, Elana

    2000-01-01

    Describes cognitive and affective characteristics of children and teenagers that may affect their Web searching behavior. Reviews literature on children's searching in online public access catalogs (OPACs) and using digital libraries. Profiles two Web search engines. Discusses some of the difficulties children have searching the Web, in the…

  11. How Users Search the Library from a Single Search Box

    Science.gov (United States)

    Lown, Cory; Sierra, Tito; Boyer, Josh

    2013-01-01

    Academic libraries are turning increasingly to unified search solutions to simplify search and discovery of library resources. Unfortunately, very little research has been published on library user search behavior in single search box environments. This study examines how users search a large public university library using a prominent, single…

  12. Earthdata Search: How Usability Drives Innovation To Enable A Broad User Base

    Science.gov (United States)

    Reese, M.; Siarto, J.; Lynnes, C.; Shum, D.

    2017-12-01

    Earthdata Search (https://search.earthdata.nasa.gov) is a modern web application allowing users to search, discover, visualize, refine, and access NASA Earth Observation data using a wide array of service offerings. Its goal is to ease the technical burden on data users by providing a high-quality application that makes it simple to interact with NASA Earth observation data, freeing them to spend more effort on innovative endeavors. This talk would detail how we put end users first in our design and development process, focusing on usability and letting usability needs drive requirements for the underlying technology. Just a few examples of how this plays out practically, Earthdata Search teams with a lightning fast metadata repository, allowing it to be an extremely responsive UI that updates as the user changes criteria not only at the dataset level, but also at the file level. This results in a better exploration experience as the time penalty is greatly reduced. Also, since Earthdata Search uses metadata from over 35,000 datasets that are managed by different data providers, metadata standards, quality and consistency will vary. We found that this was negatively impacting users' search and exploration experience. We have resolved this problem with the introduction of "humanizers", which is a community-driven process to both "smooth out" metadata values and provide non-jargonistic representations of some content within the Earthdata Search UI. This is helpful for both the experience data scientist and our users that are brand new to the discipline.

  13. Random searching

    International Nuclear Information System (INIS)

    Shlesinger, Michael F

    2009-01-01

    There are a wide variety of searching problems from molecules seeking receptor sites to predators seeking prey. The optimal search strategy can depend on constraints on time, energy, supplies or other variables. We discuss a number of cases and especially remark on the usefulness of Levy walk search patterns when the targets of the search are scarce.

  14. A simple model of bedform migration

    DEFF Research Database (Denmark)

    Bartholdy, Jesper; Ernstsen, Verner Brandbyge; Flemming, Burg W

    2010-01-01

    and width) of naturally-packed bed material on the bedform lee side, qb(crest). The model is simple, built on a rational description of simplified sediment mechanics, and its calibration constant can be explained in accordance with estimated values of the physical constants on which it is based. Predicted......A model linking subaqueous dune migration to the effective (grain related) shear stress is calibrated by means of flume data for bedform dimensions and migration rates. The effective shear stress is calculated on the basis of a new method assuming a near-bed layer above the mean bed level in which...... the current velocity accelerates towards the bedform crest. As a consequence, the effective bed shear stress corresponds to the shear stress acting directly on top of the bedform. The model operates with the critical Shields stress as a function of grain size, and predicts the deposition (volume per unit time...

  15. Fast and Accurate Identification of Cross-Linked Peptides for the Structural Analysis of Large Protein Complexes and Elucidation of Interaction Networks. / Tahir, Salman; Bukowski-Wills, Jimi-Carlo; Rasmussen, Morten; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    to investigate protein structure and protein-protein interactions. When applied to single proteins or small purified protein complexes, this methodology works well. However certain challenges arise when applied to more complex samples. One of the main problems is the combinatorial increase in the search space...... simplify a spectrum because we remove all peaks that are accounted for by the fragmentation of peptide one. This approach is highly sensitive and scales well as revealed by searching our data of synthetic cross-links against a large sequence database. Currently, against a protein database of >1300 proteins...... a spectrum is searched in 0.35 seconds - a vast improvement when compared to the exhaustive search method of combining every potential cross-link for each spectrum(60 hours). In fact the search time is comparable, if not better, than existing linear search engines. Furthermore, we auto-validate the results...

  16. Cost reduction improvement for power generation system integrating WECS using harmony search algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Ngonkham, S. [Khonkaen Univ., Amphur Muang (Thailand). Dept. of Electrical Engineering; Buasri, P. [Khonkaen Univ., Amphur Muang (Thailand). Embed System Research Group

    2009-03-11

    A harmony search (HS) algorithm was used to optimize economic dispatch (ED) in a wind energy conversion system (WECS) for power system integration. The HS algorithm was based on a stochastic random search method. System costs for the WECS system were estimated in relation to average wind speeds. The HS algorithm was implemented to optimize the ED with a simple programming procedure. The study showed that the initial parameters must be carefully selected to ensure the accuracy of the HS algorithm. The algorithm demonstrated that total costs of the WECS system were higher than costs associated with energy efficiency procedures that reduced the same amount of greenhouse gas (GHG) emissions. 7 refs,. 10 tabs., 16 figs.

  17. The Unlikely Origins of NASA’s “Search for Origins” Program

    Science.gov (United States)

    Perez, Mario R.; Thronson, Harley A.

    2017-01-01

    NASA’s Origins Program for many years was by far one of the most important scientific initiatives in NASA’s history, linking together priority research campaigns in planetary science, astrophysics, and the biological sciences. It served also as an overarching description to the agency stakeholders of a new generation of major space missions and technology investments. Moreover, the Program, although no longer formally in existence, significantly influences multiple major science priorities for NASA even today. Remarkably, inception of NASA’s Origins Program — The Search for Our Cosmic Roots — two decades ago was initiated by the country’s political leadership, not by the scientific community, the National Academy of Sciences, or by an advisory panel of experts. Instead, it was an initiative by the White House in response to the stunning announcement of ‘evidence’ for life found on a Martian meteorite not long after the discovery of the first extrasolar planet orbiting a sun-like star. A White House memo dated in September 1996, written by John H. Gibbons, Assistant to the President for Science and Technology to Dan Goldin, NASA Administrator at that time, called for a “Space Summit” that would include experts on three broad topics: the universe, planets, and life.The summit was jointly organized by NASA and the National Research Council, and was chaired by Vice-President Al Gore in late October 1996. Three dozen biologists, planetary scientists, astronomers, and cosmologists participated. The outcome was the Origins Program, which has been a prominent part of NASA’s science program ever since, theme which is captured by the simple and profound questions: How Did We Get Here? and Are We Alone?This particular initiative and its genesis demonstrates that science discoveries, followed by political activism and then executive orders can impact and shape for decades the paths to major science priorities, practices, and implementation. In this

  18. An Integrated Approach for Reliable Facility Location/Network Design Problem with Link Disruption

    Directory of Open Access Journals (Sweden)

    Davood Shishebori

    2015-05-01

    Full Text Available Proposing a robust designed facility location is one of the most effective ways to hedge against unexpected disruptions and failures in a transportation network system. This paper considers the combined facility location/network design problem with regard to transportation link disruptions and develops a mixed integer linear programming formulation to model it. With respect to the probability of link disruptions, the objective function of the model minimizes the total costs, including location costs, link construction costs and also the expected transportation costs. An efficient hybrid algorithm based on LP relaxation and variable neighbourhood search metaheuristic is developed in order to solve the mathematical model. Numerical results demonstrate that the proposed hybrid algorithm has suitable efficiency in terms of duration of solution time and determining excellent solution quality.

  19. Open Search Environments: The Free Alternative to Commercial Search Services

    Directory of Open Access Journals (Sweden)

    Adrian O'Riordan

    2014-06-01

    Full Text Available Open search systems present a free and less restricted alternative to commercial search services. This paper explores the space of open search technology looking in particular at the issue of interoperability. A description of current protocols and formats for engineering open search applications is presented. The suitability of these technologies and issues around their adoption and operation are discussed. This open search approach is especially proving a fitting choice in applications involving the harvesting of resources and information integration. Principal among the technological solutions are OpenSearch and SRU. OpenSearch and SRU implement a federated model to enable existing and new search engines and search clients communicate. Applications and instances where Opensearch and SRU can be combined are presented. Other relevant technologies such as OpenURL, Apache Solr, and OAI-PMH are also discussed. The deployment of these freely licensed open standards in digital library applications is now a genuine alternative to commercial or proprietary systems.

  20. The CCSDS Next Generation Space Data Link Protocol (NGSLP)

    Science.gov (United States)

    Kazz, Greg J.; Greenberg, Edward

    2014-01-01

    The CCSDS space link protocols i.e., Telemetry (TM), Telecommand (TC), Advanced Orbiting Systems (AOS) were developed in the early growth period of the space program. They were designed to meet the needs of the early missions, be compatible with the available technology and focused on the specific link environments. Digital technology was in its infancy and spacecraft power and mass issues enforced severe constraints on flight implementations. Therefore the Telecommand protocol was designed around a simple Bose, Hocquenghem, Chaudhuri (BCH) code that provided little coding gain and limited error detection but was relatively simple to decode on board. The infusion of the concatenated Convolutional and Reed-Solomon codes5 for telemetry was a major milestone and transformed telemetry applications by providing them the ability to more efficiently utilize the telemetry link and its ability to deliver user data. The ability to significantly lower the error rates on the telemetry links enabled the use of packet telemetry and data compression. The infusion of the high performance codes for telemetry was enabled by the advent of digital processing, but it was limited to earth based systems supporting telemetry. The latest CCSDS space link protocol, Proximity-1 was developed in early 2000 to meet the needs of short-range, bi-directional, fixed or mobile radio links characterized by short time delays, moderate but not weak signals, and short independent sessions. Proximity-1 has been successfully deployed on both NASA and ESA missions at Mars and is planned to be utilized by all Mars missions in development. A new age has arisen, one that now provides the means to perform advanced digital processing in spacecraft systems enabling the use of improved transponders, digital correlators, and high performance forward error correcting codes for all communications links. Flight transponders utilizing digital technology have emerged and can efficiently provide the means to make the

  1. How Will Online Affiliate Marketing Networks Impact Search Engine Rankings?

    OpenAIRE

    Janssen, David; Heck, Eric

    2007-01-01

    textabstractIn online affiliate marketing networks advertising web sites offer their affiliates revenues based on provided web site traffic and associated leads and sales. Advertising web sites can have a network of thousands of affiliates providing them with web site traffic through hyperlinks on their web sites. Search engines such as Google, MSN, and Yahoo, consider hyperlinks as a proof of quality and/or reliability of the linked web sites, and therefore use them to determine the relevanc...

  2. Simple and tight monogamy relations for a class of Bell inequalities

    Science.gov (United States)

    Augusiak, Remigiusz

    2017-01-01

    Physical principles constrain the way nonlocal correlations can be distributed among distant parties in a Bell-type experiment. These constraints are usually expressed by monogamy relations that bound the amount of Bell inequality violation observed by a set of parties by the violation observed by a different set of parties. Here we show that the no-signaling principle yields simple and tight monogamy relations for an important class of bipartite and multipartite Bell inequalities. We also link these trade-offs to the guessing probability—a key quantity in device-independent information processing.

  3. A simple magic cup to inject excitement and curiosity in physics

    Science.gov (United States)

    Amir, Nazir

    2018-05-01

    This article highlights a simple demonstration kit that can be easily fabricated in Design & Technology (D&T) workshops to inject excitement and curiosity into students’ learning of physics concepts such as density and optics. Using an ice cream cup from a fast food restaurant and a transparent circular acrylic piece, students can be guided to make a ‘magic’ cup, while at the same time get inquisitive about the physics behind the magic. The project highlights a way of linking physics to D&T in a feasible manner which can motivate and engage students.

  4. The influence that JavaScript(TM has on the visibility of a Website to search engines - a pilot study

    Directory of Open Access Journals (Sweden)

    M. Weideman

    2006-01-01

    Full Text Available Introduction. In this research project, an empirical pilot study on the relationship between JavaScript(TM usage and Website visibility was carried out. The main purpose was to establish whethe JavaScript(TM-based hyperlinks attract or repel crawlers, resulting in an increase or decrease in Website visibility. Method. A literature survey has established that there appears to be contradiction amongst claims by various authors as to whether or not crawlers can parse or interpret JavaScript(TM. The chosen methodology involved the creation of a Website that contains different kinds of links to other pages, where actual data files were stored. Search engine crawler visits to the page pointed to by the different kinds of links were monitored and recorded. Analysis. This experiment took into account the fact that JavaScript(TM can be embedded within the HTML of a Web page or referenced as an external '.js' file. It also considered different ways of specifying links within JavaScript(TM. Results. The results obtained indicated that text links provide the highest level of opportunity for crawlers to discover and index non-homepages. In general, crawlers did not follow Javascript(TM-based links to Web pages blindly. Conclusion. . Most crawlers evade Javascript(TM links, implying that Web pages using forms of this technology, for example in pop-up/pull-down menus, could be jeopardising their chances of achieving high search engine rankings. Certain Javascript(TM links were not followed at all, which has serious implications for designers of e-Commerce Websites.

  5. Connecting Archaeological Data and Grey Literature via Semantic Cross Search

    Directory of Open Access Journals (Sweden)

    Douglas Tudhope

    2011-07-01

    Full Text Available Differing terminology and database structure hinders meaningful cross search of excavation datasets. Matching free text grey literature reports with datasets poses yet more challenges. Conventional search techniques are unable to cross search between archaeological datasets and Web-based grey literature. Results are reported from two AHRC funded research projects that investigated the use of semantic techniques to link digital archive databases, vocabularies and associated grey literature. STAR (Semantic Technologies for Archaeological Resources was a collaboration between the University of Glamorgan, Hypermedia Research Unit and English Heritage (EH. The main outcome is a research Demonstrator (available online, which cross searches over excavation datasets from different database schemas, including Raunds Roman, Raunds Prehistoric, Museum of London, Silchester Roman and Stanwick sampling. The system additionally cross searches over an extract of excavation reports from the OASIS index of grey literature, operated by the Archaeology Data Service (ADS. A conceptual framework provided by the CIDOC Conceptual Reference Model (CRM integrates the different database structures and the metadata automatically generated from the OASIS reports by natural language processing techniques. The methods employed for extracting semantic RDF representations from the datasets and the information extraction from grey literature are described. The STELLAR project provides freely available tools to reduce the costs of mapping and extracting data to semantic search systems such as the Demonstrator and to linked data representation generally. Detailed use scenarios (and a screen capture video provide a basis for a discussion of key issues, including cost-benefits, ontology modelling, mapping, terminology control, semantic implementation and information extraction issues. The scenarios show that semantic interoperability can be achieved by mapping and extracting

  6. Implementation of the Grover search algorithm with Josephson charge qubits

    International Nuclear Information System (INIS)

    Zheng Xiaohu; Dong Ping; Xue Zhengyuan; Cao Zhuoliang

    2007-01-01

    A scheme of implementing the Grover search algorithm based on Josephson charge qubits has been proposed, which would be a key step to scale more complex quantum algorithms and very important for constructing a real quantum computer via Josephson charge qubits. The present scheme is simple but fairly efficient, and easily manipulated because any two-charge-qubit can be selectively and effectively coupled by a common inductance. More manipulations can be carried out before decoherence sets in. Our scheme can be realized within the current technology

  7. LitVar: a semantic search engine for linking genomic variant data in PubMed and PMC.

    Science.gov (United States)

    Allot, Alexis; Peng, Yifan; Wei, Chih-Hsuan; Lee, Kyubum; Phan, Lon; Lu, Zhiyong

    2018-05-14

    The identification and interpretation of genomic variants play a key role in the diagnosis of genetic diseases and related research. These tasks increasingly rely on accessing relevant manually curated information from domain databases (e.g. SwissProt or ClinVar). However, due to the sheer volume of medical literature and high cost of expert curation, curated variant information in existing databases are often incomplete and out-of-date. In addition, the same genetic variant can be mentioned in publications with various names (e.g. 'A146T' versus 'c.436G>A' versus 'rs121913527'). A search in PubMed using only one name usually cannot retrieve all relevant articles for the variant of interest. Hence, to help scientists, healthcare professionals, and database curators find the most up-to-date published variant research, we have developed LitVar for the search and retrieval of standardized variant information. In addition, LitVar uses advanced text mining techniques to compute and extract relationships between variants and other associated entities such as diseases and chemicals/drugs. LitVar is publicly available at https://www.ncbi.nlm.nih.gov/CBBresearch/Lu/Demo/LitVar.

  8. Eye movements, visual search and scene memory, in an immersive virtual environment.

    Directory of Open Access Journals (Sweden)

    Dmitry Kit

    Full Text Available Visual memory has been demonstrated to play a role in both visual search and attentional prioritization in natural scenes. However, it has been studied predominantly in experimental paradigms using multiple two-dimensional images. Natural experience, however, entails prolonged immersion in a limited number of three-dimensional environments. The goal of the present experiment was to recreate circumstances comparable to natural visual experience in order to evaluate the role of scene memory in guiding eye movements in a natural environment. Subjects performed a continuous visual-search task within an immersive virtual-reality environment over three days. We found that, similar to two-dimensional contexts, viewers rapidly learn the location of objects in the environment over time, and use spatial memory to guide search. Incidental fixations did not provide obvious benefit to subsequent search, suggesting that semantic contextual cues may often be just as efficient, or that many incidentally fixated items are not held in memory in the absence of a specific task. On the third day of the experience in the environment, previous search items changed in color. These items were fixated upon with increased probability relative to control objects, suggesting that memory-guided prioritization (or Surprise may be a robust mechanisms for attracting gaze to novel features of natural environments, in addition to task factors and simple spatial saliency.

  9. Eye movements, visual search and scene memory, in an immersive virtual environment.

    Science.gov (United States)

    Kit, Dmitry; Katz, Leor; Sullivan, Brian; Snyder, Kat; Ballard, Dana; Hayhoe, Mary

    2014-01-01

    Visual memory has been demonstrated to play a role in both visual search and attentional prioritization in natural scenes. However, it has been studied predominantly in experimental paradigms using multiple two-dimensional images. Natural experience, however, entails prolonged immersion in a limited number of three-dimensional environments. The goal of the present experiment was to recreate circumstances comparable to natural visual experience in order to evaluate the role of scene memory in guiding eye movements in a natural environment. Subjects performed a continuous visual-search task within an immersive virtual-reality environment over three days. We found that, similar to two-dimensional contexts, viewers rapidly learn the location of objects in the environment over time, and use spatial memory to guide search. Incidental fixations did not provide obvious benefit to subsequent search, suggesting that semantic contextual cues may often be just as efficient, or that many incidentally fixated items are not held in memory in the absence of a specific task. On the third day of the experience in the environment, previous search items changed in color. These items were fixated upon with increased probability relative to control objects, suggesting that memory-guided prioritization (or Surprise) may be a robust mechanisms for attracting gaze to novel features of natural environments, in addition to task factors and simple spatial saliency.

  10. Substring Position Search over Encrypted Cloud Data Supporting Efficient Multi-User Setup

    Directory of Open Access Journals (Sweden)

    Mikhail Strizhov

    2016-07-01

    Full Text Available Existing Searchable Encryption (SE solutions are able to handle simple Boolean search queries, such as single or multi-keyword queries, but cannot handle substring search queries over encrypted data that also involve identifying the position of the substring within the document. These types of queries are relevant in areas such as searching DNA data. In this paper, we propose a tree-based Substring Position Searchable Symmetric Encryption (SSP-SSE to overcome the existing gap. Our solution efficiently finds occurrences of a given substring over encrypted cloud data. Specifically, our construction uses the position heap tree data structure and achieves asymptotic efficiency comparable to that of an unencrypted position heap tree. Our encryption takes O ( k n time, and the resulting ciphertext is of size O ( k n , where k is a security parameter and n is the size of stored data. The search takes O ( m 2 + o c c time and three rounds of communication, where m is the length of the queried substring and o c c is the number of occurrences of the substring in the document collection. We prove that the proposed scheme is secure against chosen-query attacks that involve an adaptive adversary. Finally, we extend SSP-SSE to the multi-user setting where an arbitrary group of cloud users can submit substring queries to search the encrypted data.

  11. Why should we publish Linked Data?

    Science.gov (United States)

    Blower, Jon; Riechert, Maik; Koubarakis, Manolis; Pace, Nino

    2016-04-01

    publishing Linked Data will result in tangible user benefits. This presentation will address a number of these issues, using real-world experience gathered from four recent European projects: MELODIES (http://melodiesproject.eu), LEO (http://linkedeodata.eu), CHARMe (http://linkedeodata.eu) and TELEIOS (http://www.earthobservatory.eu). These projects have all applied Linked Data techniques in practical, real-world situations involving the use of diverse data (including earth science data) by both industrial and academic users. Specifically, we will: • Identify a set of practical and valuable uses for Linked Data, focusing on areas where Linked Data fills gaps left by other technologies. These uses include: enabling the discovery of earth science data using mass-market search engines, helping users to understand data and its uses, combining data from multiple sources and enabling the annotation of data by users. • Enumerate some common challenges faced by developers of data-driven services who wish to use Linked Data in their applications. • Describe a new suite of tools for managing, processing and visualising Linked Data in earth science applications (including geospatial Linked Data).

  12. LAILAPS: the plant science search engine.

    Science.gov (United States)

    Esch, Maria; Chen, Jinbo; Colmsee, Christian; Klapperstück, Matthias; Grafahrend-Belau, Eva; Scholz, Uwe; Lange, Matthias

    2015-01-01

    With the number of sequenced plant genomes growing, the number of predicted genes and functional annotations is also increasing. The association between genes and phenotypic traits is currently of great interest. Unfortunately, the information available today is widely scattered over a number of different databases. Information retrieval (IR) has become an all-encompassing bioinformatics methodology for extracting knowledge from complex, heterogeneous and distributed databases, and therefore can be a useful tool for obtaining a comprehensive view of plant genomics, from genes to traits. Here we describe LAILAPS (http://lailaps.ipk-gatersleben.de), an IR system designed to link plant genomic data in the context of phenotypic attributes for a detailed forward genetic research. LAILAPS comprises around 65 million indexed documents, encompassing >13 major life science databases with around 80 million links to plant genomic resources. The LAILAPS search engine allows fuzzy querying for candidate genes linked to specific traits over a loosely integrated system of indexed and interlinked genome databases. Query assistance and an evidence-based annotation system enable time-efficient and comprehensive information retrieval. An artificial neural network incorporating user feedback and behavior tracking allows relevance sorting of results. We fully describe LAILAPS's functionality and capabilities by comparing this system's performance with other widely used systems and by reporting both a validation in maize and a knowledge discovery use-case focusing on candidate genes in barley. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists.

  13. Generating and Executing Complex Natural Language Queries across Linked Data.

    Science.gov (United States)

    Hamon, Thierry; Mougin, Fleur; Grabar, Natalia

    2015-01-01

    With the recent and intensive research in the biomedical area, the knowledge accumulated is disseminated through various knowledge bases. Links between these knowledge bases are needed in order to use them jointly. Linked Data, SPARQL language, and interfaces in Natural Language question-answering provide interesting solutions for querying such knowledge bases. We propose a method for translating natural language questions in SPARQL queries. We use Natural Language Processing tools, semantic resources, and the RDF triples description. The method is designed on 50 questions over 3 biomedical knowledge bases, and evaluated on 27 questions. It achieves 0.78 F-measure on the test set. The method for translating natural language questions into SPARQL queries is implemented as Perl module available at http://search.cpan.org/ thhamon/RDF-NLP-SPARQLQuery.

  14. Library Catalogue Users Are Influenced by Trends in Web Searching Search Strategies. A review of: Novotny, Eric. “I Don’t Think I Click: A Protocol Analysis Study of Use of a Library Online Catalog in the Internet Age.” College & Research Libraries, 65.6 (Nov. 2004: 525-37.

    Directory of Open Access Journals (Sweden)

    Susan Haigh

    2006-09-01

    Full Text Available Objective – To explore how Web-savvy users think about and search an online catalogue. Design – Protocol analysis study. Setting – Academic library (Pennsylvania State University Libraries. Subjects – Eighteen users (17 students, 1 faculty member of an online public access catalog, divided into two groups of nine first-time and nine experienced users. Method – The study team developed five tasks that represented a range of activities commonly performed by library users, such as searching for a specific item, identifying a library location, and requesting a copy. Seventeen students and one faculty member, divided evenly between novice and experienced searchers, were recruited to “think aloud” through the performance of the tasks. Data were gathered through audio recordings, screen capture software, and investigator notes. The time taken for each task was recorded, and investigators rated task completion as “successful,” “partially successful,” “fail,” or “search aborted.” After the searching session, participants were interviewed to clarify their actions and provide further commentary on the catalogue search. Main results – Participants in both test groups were relatively unsophisticated subject searchers. They made minimal use of Boolean operators, and tended not to repair failed searches by rethinking the search vocabulary and using synonyms. Participants did not have a strong understanding of library catalogue contents or structure and showed little curiosity in developing an understanding of how to utilize the catalogue. Novice users were impatient both in choosing search options and in evaluating their search results. They assumed search results were sorted by relevance, and thus would not typically browse past the initial screen. They quickly followed links, fearlessly tried different searches and options, and rapidly abandoned false trails. Experienced users were more effective and efficient searchers than

  15. Clinician search behaviors may be influenced by search engine design.

    Science.gov (United States)

    Lau, Annie Y S; Coiera, Enrico; Zrimec, Tatjana; Compton, Paul

    2010-06-30

    Searching the Web for documents using information retrieval systems plays an important part in clinicians' practice of evidence-based medicine. While much research focuses on the design of methods to retrieve documents, there has been little examination of the way different search engine capabilities influence clinician search behaviors. Previous studies have shown that use of task-based search engines allows for faster searches with no loss of decision accuracy compared with resource-based engines. We hypothesized that changes in search behaviors may explain these differences. In all, 75 clinicians (44 doctors and 31 clinical nurse consultants) were randomized to use either a resource-based or a task-based version of a clinical information retrieval system to answer questions about 8 clinical scenarios in a controlled setting in a university computer laboratory. Clinicians using the resource-based system could select 1 of 6 resources, such as PubMed; clinicians using the task-based system could select 1 of 6 clinical tasks, such as diagnosis. Clinicians in both systems could reformulate search queries. System logs unobtrusively capturing clinicians' interactions with the systems were coded and analyzed for clinicians' search actions and query reformulation strategies. The most frequent search action of clinicians using the resource-based system was to explore a new resource with the same query, that is, these clinicians exhibited a "breadth-first" search behaviour. Of 1398 search actions, clinicians using the resource-based system conducted 401 (28.7%, 95% confidence interval [CI] 26.37-31.11) in this way. In contrast, the majority of clinicians using the task-based system exhibited a "depth-first" search behavior in which they reformulated query keywords while keeping to the same task profiles. Of 585 search actions conducted by clinicians using the task-based system, 379 (64.8%, 95% CI 60.83-68.55) were conducted in this way. This study provides evidence that

  16. Evolutionary Policy Transfer and Search Methods for Boosting Behavior Quality: RoboCup Keep-Away Case Study

    Directory of Open Access Journals (Sweden)

    Geoff Nitschke

    2017-11-01

    Full Text Available This study evaluates various evolutionary search methods to direct neural controller evolution in company with policy (behavior transfer across increasingly complex collective robotic (RoboCup keep-away tasks. Robot behaviors are first evolved in a source task and then transferred for further evolution to more complex target tasks. Evolutionary search methods tested include objective-based search (fitness function, behavioral and genotypic diversity maintenance, and hybrids of such diversity maintenance and objective-based search. Evolved behavior quality is evaluated according to effectiveness and efficiency. Effectiveness is the average task performance of transferred and evolved behaviors, where task performance is the average time the ball is controlled by a keeper team. Efficiency is the average number of generations taken for the fittest evolved behaviors to reach a minimum task performance threshold given policy transfer. Results indicate that policy transfer coupled with hybridized evolution (behavioral diversity maintenance and objective-based search addresses the bootstrapping problem for increasingly complex keep-away tasks. That is, this hybrid method (coupled with policy transfer evolves behaviors that could not otherwise be evolved. Also, this hybrid evolutionary search was demonstrated as consistently evolving topologically simple neural controllers that elicited high-quality behaviors.

  17. Modeling of pheromone communication system of forest Lepidopterous insects. II. Model of female searching by male

    Directory of Open Access Journals (Sweden)

    A. V. Kovalev

    2015-06-01

    Full Text Available We propose an agent­based simulation model search. This model allows us to evaluate the effectiveness of different males­females pheromone search strategies for Lepidoptera. In the model, we consider the simplest case of the search, when the pheromone has only one chemical component. It is assumed that the insects are able to detect the pheromone molecules and the sensory cells generate action potentials in contact with the pheromone for some time. Thereafter pheromone molecule is inactivated. This behavior can be regarded as a memory of individual. Proportion of individuals who have reached the source is selected as an integral indicator of the search efficiency. To evaluate the effectiveness, numeric experiments were performed in different conditions: random walk, search algorithm without memory, and algorithm with memory and return mechanism. The resulting effectiveness of source localization by insects for flight in turbulent flows is ~ 70 %, which corresponds to experiments with live specimens in literature. In this case, proposed pheromone search algorithm is quite simple, which makes it biologically correct. Conducted modeling calculations can be the starting point for planning of field observations and pest monitoring systems using pheromone traps.

  18. Colleagues and Competitors: How Internal Social Comparisons Shape Organizational Search and Adaptation

    DEFF Research Database (Denmark)

    Baumann, Oliver; Eggers, JP; Stieglitz, Nils

    2018-01-01

    Intra-organizational comparisons—managers and units benchmarking their performance against each other—can turn colleagues into competitors. To better understand when organizations should allow or even encourage internal social comparisons, we study their implications for organizational adaptation....... We highlight empirical implications and discuss theoretical links to work on intra-organizational competition, social comparisons and aspiration-driven search, diversification and performance, and the adaptation of multi-business firms....

  19. Cube search, revisited

    Science.gov (United States)

    Zhang, Xuetao; Huang, Jie; Yigit-Elliott, Serap; Rosenholtz, Ruth

    2015-01-01

    Observers can quickly search among shaded cubes for one lit from a unique direction. However, replace the cubes with similar 2-D patterns that do not appear to have a 3-D shape, and search difficulty increases. These results have challenged models of visual search and attention. We demonstrate that cube search displays differ from those with “equivalent” 2-D search items in terms of the informativeness of fairly low-level image statistics. This informativeness predicts peripheral discriminability of target-present from target-absent patches, which in turn predicts visual search performance, across a wide range of conditions. Comparing model performance on a number of classic search tasks, cube search does not appear unexpectedly easy. Easy cube search, per se, does not provide evidence for preattentive computation of 3-D scene properties. However, search asymmetries derived from rotating and/or flipping the cube search displays cannot be explained by the information in our current set of image statistics. This may merely suggest a need to modify the model's set of 2-D image statistics. Alternatively, it may be difficult cube search that provides evidence for preattentive computation of 3-D scene properties. By attributing 2-D luminance variations to a shaded 3-D shape, 3-D scene understanding may slow search for 2-D features of the target. PMID:25780063

  20. Inability of keratinocytes lacking their specific transglutaminase to form cross-linked envelopes: Absence of envelopes as a simple diagnostic test for lamellar ichthyosis

    OpenAIRE

    Jeon, Saewha; Djian, Philippe; Green, Howard

    1998-01-01

    Epidermal keratinocytes, late in their terminal differentiation, form cross-linked envelopes resistant to ionic detergent and reducing agent. Because the cross-linking process is catalyzed by the keratinocyte transglutaminase, the absence of active transglutaminase should result in failure of the keratinocyte to form a cross-linked envelope. Three keratinocyte strains bearing mutations in the keratinocyte transglutaminase were examined: two contained no detectable transglutaminase mRNA and no...

  1. Searching the ASRS Database Using QUORUM Keyword Search, Phrase Search, Phrase Generation, and Phrase Discovery

    Science.gov (United States)

    McGreevy, Michael W.; Connors, Mary M. (Technical Monitor)

    2001-01-01

    To support Search Requests and Quick Responses at the Aviation Safety Reporting System (ASRS), four new QUORUM methods have been developed: keyword search, phrase search, phrase generation, and phrase discovery. These methods build upon the core QUORUM methods of text analysis, modeling, and relevance-ranking. QUORUM keyword search retrieves ASRS incident narratives that contain one or more user-specified keywords in typical or selected contexts, and ranks the narratives on their relevance to the keywords in context. QUORUM phrase search retrieves narratives that contain one or more user-specified phrases, and ranks the narratives on their relevance to the phrases. QUORUM phrase generation produces a list of phrases from the ASRS database that contain a user-specified word or phrase. QUORUM phrase discovery finds phrases that are related to topics of interest. Phrase generation and phrase discovery are particularly useful for finding query phrases for input to QUORUM phrase search. The presentation of the new QUORUM methods includes: a brief review of the underlying core QUORUM methods; an overview of the new methods; numerous, concrete examples of ASRS database searches using the new methods; discussion of related methods; and, in the appendices, detailed descriptions of the new methods.

  2. A PORTRAIT OF COLD GAS IN GALAXIES AT 60 pc RESOLUTION AND A SIMPLE METHOD TO TEST HYPOTHESES THAT LINK SMALL-SCALE ISM STRUCTURE TO GALAXY-SCALE PROCESSES

    International Nuclear Information System (INIS)

    Leroy, Adam K.; Hughes, Annie; Schruba, Andreas; Rosolowsky, Erik; Blanc, Guillermo A.; Escala, Andres; Bolatto, Alberto D.; Colombo, Dario; Kramer, Carsten; Kruijssen, J. M. Diederik; Meidt, Sharon; Querejeta, Miguel; Schinnerer, Eva; Sliwa, Kazimierz; Pety, Jerome; Sandstrom, Karin

    2016-01-01

    The cloud-scale density, velocity dispersion, and gravitational boundedness of the interstellar medium (ISM) vary within and among galaxies. In turbulent models, these properties play key roles in the ability of gas to form stars. New high-fidelity, high-resolution surveys offer the prospect to measure these quantities across galaxies. We present a simple approach to make such measurements and to test hypotheses that link small-scale gas structure to star formation and galactic environment. Our calculations capture the key physics of the Larson scaling relations, and we show good correspondence between our approach and a traditional “cloud properties” treatment. However, we argue that our method is preferable in many cases because of its simple, reproducible characterization of all emission. Using, low- J 12 CO data from recent surveys, we characterize the molecular ISM at 60 pc resolution in the Antennae, the Large Magellanic Cloud (LMC), M31, M33, M51, and M74. We report the distributions of surface density, velocity dispersion, and gravitational boundedness at 60 pc scales and show galaxy-to-galaxy and intragalaxy variations in each. The distribution of flux as a function of surface density appears roughly lognormal with a 1 σ width of ∼0.3 dex, though the center of this distribution varies from galaxy to galaxy. The 60 pc resolution line width and molecular gas surface density correlate well, which is a fundamental behavior expected for virialized or free-falling gas. Varying the measurement scale for the LMC and M31, we show that the molecular ISM has higher surface densities, lower line widths, and more self-gravity at smaller scales.

  3. A PORTRAIT OF COLD GAS IN GALAXIES AT 60 pc RESOLUTION AND A SIMPLE METHOD TO TEST HYPOTHESES THAT LINK SMALL-SCALE ISM STRUCTURE TO GALAXY-SCALE PROCESSES

    Energy Technology Data Exchange (ETDEWEB)

    Leroy, Adam K. [Department of Astronomy, The Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Hughes, Annie [CNRS, IRAP, 9 av. du Colonel Roche, BP 44346, F-31028 Toulouse cedex 4 (France); Schruba, Andreas [Max-Planck-Institut für extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Rosolowsky, Erik [Department of Physics, University of Alberta, Edmonton, AB (Canada); Blanc, Guillermo A.; Escala, Andres [Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago (Chile); Bolatto, Alberto D. [Department of Astronomy, Laboratory for Millimeter-wave Astronomy, and Joint Space Institute, University of Maryland, College Park, MD 20742 (United States); Colombo, Dario [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany); Kramer, Carsten [Instituto Radioastronomía Milimétrica (IRAM), Av. Divina Pastora 7, Nucleo Central, E-18012 Granada (Spain); Kruijssen, J. M. Diederik [Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg, Mönchhofstrasse 12-14, D-69120 Heidelberg (Germany); Meidt, Sharon; Querejeta, Miguel; Schinnerer, Eva; Sliwa, Kazimierz [Max Planck Institute für Astronomie, Königstuhl 17, D-69117, Heidelberg (Germany); Pety, Jerome [Institut de Radioastronomie Millimtrique (IRAM), 300 Rue de la Piscine, F-38406 Saint-Martin-d’Hères (France); Sandstrom, Karin [Center for Astrophysics and Space Sciences, Department of Physics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 (United States); and others

    2016-11-01

    The cloud-scale density, velocity dispersion, and gravitational boundedness of the interstellar medium (ISM) vary within and among galaxies. In turbulent models, these properties play key roles in the ability of gas to form stars. New high-fidelity, high-resolution surveys offer the prospect to measure these quantities across galaxies. We present a simple approach to make such measurements and to test hypotheses that link small-scale gas structure to star formation and galactic environment. Our calculations capture the key physics of the Larson scaling relations, and we show good correspondence between our approach and a traditional “cloud properties” treatment. However, we argue that our method is preferable in many cases because of its simple, reproducible characterization of all emission. Using, low- J {sup 12}CO data from recent surveys, we characterize the molecular ISM at 60 pc resolution in the Antennae, the Large Magellanic Cloud (LMC), M31, M33, M51, and M74. We report the distributions of surface density, velocity dispersion, and gravitational boundedness at 60 pc scales and show galaxy-to-galaxy and intragalaxy variations in each. The distribution of flux as a function of surface density appears roughly lognormal with a 1 σ width of ∼0.3 dex, though the center of this distribution varies from galaxy to galaxy. The 60 pc resolution line width and molecular gas surface density correlate well, which is a fundamental behavior expected for virialized or free-falling gas. Varying the measurement scale for the LMC and M31, we show that the molecular ISM has higher surface densities, lower line widths, and more self-gravity at smaller scales.

  4. A hybrid search algorithm for swarm robots searching in an unknown environment.

    Science.gov (United States)

    Li, Shoutao; Li, Lina; Lee, Gordon; Zhang, Hao

    2014-01-01

    This paper proposes a novel method to improve the efficiency of a swarm of robots searching in an unknown environment. The approach focuses on the process of feeding and individual coordination characteristics inspired by the foraging behavior in nature. A predatory strategy was used for searching; hence, this hybrid approach integrated a random search technique with a dynamic particle swarm optimization (DPSO) search algorithm. If a search robot could not find any target information, it used a random search algorithm for a global search. If the robot found any target information in a region, the DPSO search algorithm was used for a local search. This particle swarm optimization search algorithm is dynamic as all the parameters in the algorithm are refreshed synchronously through a communication mechanism until the robots find the target position, after which, the robots fall back to a random searching mode. Thus, in this searching strategy, the robots alternated between two searching algorithms until the whole area was covered. During the searching process, the robots used a local communication mechanism to share map information and DPSO parameters to reduce the communication burden and overcome hardware limitations. If the search area is very large, search efficiency may be greatly reduced if only one robot searches an entire region given the limited resources available and time constraints. In this research we divided the entire search area into several subregions, selected a target utility function to determine which subregion should be initially searched and thereby reduced the residence time of the target to improve search efficiency.

  5. Visual search performance in infants associates with later ASD diagnosis.

    Science.gov (United States)

    Cheung, C H M; Bedford, R; Johnson, M H; Charman, T; Gliga, T

    2018-01-01

    An enhanced ability to detect visual targets amongst distractors, known as visual search (VS), has often been documented in Autism Spectrum Disorders (ASD). Yet, it is unclear when this behaviour emerges in development and if it is specific to ASD. We followed up infants at high and low familial risk for ASD to investigate how early VS abilities links to later ASD diagnosis, the potential underlying mechanisms of this association and the specificity of superior VS to ASD. Clinical diagnosis of ASD as well as dimensional measures of ASD, attention-deficit/hyperactivity disorder (ADHD) and anxiety symptoms were ascertained at 3 years. At 9 and 15 months, but not at age 2 years, high-risk children who later met clinical criteria for ASD (HR-ASD) had better VS performance than those without later diagnosis and low-risk controls. Although HR-ASD children were also more attentive to the task at 9 months, this did not explain search performance. Superior VS specifically predicted 3 year-old ASD but not ADHD or anxiety symptoms. Our results demonstrate that atypical perception and core ASD symptoms of social interaction and communication are closely and selectively associated during early development, and suggest causal links between perceptual and social features of ASD. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  6. Top-k Keyword Search Over Graphs Based On Backward Search

    Directory of Open Access Journals (Sweden)

    Zeng Jia-Hui

    2017-01-01

    Full Text Available Keyword search is one of the most friendly and intuitive information retrieval methods. Using the keyword search to get the connected subgraph has a lot of application in the graph-based cognitive computation, and it is a basic technology. This paper focuses on the top-k keyword searching over graphs. We implemented a keyword search algorithm which applies the backward search idea. The algorithm locates the keyword vertices firstly, and then applies backward search to find rooted trees that contain query keywords. The experiment shows that query time is affected by the iteration number of the algorithm.

  7. People searching for people: analysis of a people search engine log

    NARCIS (Netherlands)

    Weerkamp, W.; Berendsen, R.; Kovachev, B.; Meij, E.; Balog, K.; de Rijke, M.

    2011-01-01

    Recent years show an increasing interest in vertical search: searching within a particular type of information. Understanding what people search for in these "verticals" gives direction to research and provides pointers for the search engines themselves. In this paper we analyze the search logs of

  8. Internet Databases of the Properties, Enzymatic Reactions, and Metabolism of Small Molecules—Search Options and Applications in Food Science

    Directory of Open Access Journals (Sweden)

    Piotr Minkiewicz

    2016-12-01

    Full Text Available Internet databases of small molecules, their enzymatic reactions, and metabolism have emerged as useful tools in food science. Database searching is also introduced as part of chemistry or enzymology courses for food technology students. Such resources support the search for information about single compounds and facilitate the introduction of secondary analyses of large datasets. Information can be retrieved from databases by searching for the compound name or structure, annotating with the help of chemical codes or drawn using molecule editing software. Data mining options may be enhanced by navigating through a network of links and cross-links between databases. Exemplary databases reviewed in this article belong to two classes: tools concerning small molecules (including general and specialized databases annotating food components and tools annotating enzymes and metabolism. Some problems associated with database application are also discussed. Data summarized in computer databases may be used for calculation of daily intake of bioactive compounds, prediction of metabolism of food components, and their biological activity as well as for prediction of interactions between food component and drugs.

  9. Estimation of the gravitational wave polarizations from a nontemplate search

    Science.gov (United States)

    Di Palma, Irene; Drago, Marco

    2018-01-01

    Gravitational wave astronomy is just beginning, after the recent success of the four direct detections of binary black hole (BBH) mergers and the first observation from a binary neutron star inspiral, with the expectation of many more events to come. Given the possibility to detect waves from not exactly modeled astrophysical processes, it is fundamental to be ready to calculate the polarization waveforms in the case of searches using nontemplate algorithms. In such a case, the waveform polarizations are the only quantities that contain direct information about the generating process. We present the performance of a new valuable tool to estimate the inverse solution of gravitational wave transient signals, starting from the analysis of the signal properties of a nontemplate algorithm that is open to a wider class of gravitational signals not covered by template algorithms. We highlight the contributions to the wave polarization associated with the detector response, the sky localization, and the polarization angle of the source. In this paper we present the performances of such a method and its implications by using two main classes of transient signals, resembling the limiting case for most simple and complicated morphologies. The performances are encouraging for the tested waveforms: the correlation between the original and the reconstructed waveforms spans from better than 80% for simple morphologies to better than 50% for complicated ones. For a nontemplate search these results can be considered satisfactory to reconstruct the astrophysical progenitor.

  10. BredeQuery: Coordinate-Based Meta-analytic Search of Neuroscientific Literature from the SPM Environment

    DEFF Research Database (Denmark)

    Wilkowski, Bartlomiej; Szewczyk, Marcin Marek; Rasmussen, Peter Mondrup

    2010-01-01

    Query offers a direct link from SPM to the Brede Database coordinate-based search engine. BredeQuery is able to ‘grab’ brain location coordinates from the SPM windows and enter them as a query for the Brede Database. Moreover, results of the query can be displayed in a MATLAB window and/or exported directly...

  11. Towards linked open gene mutations data

    Science.gov (United States)

    2012-01-01

    Background With the advent of high-throughput technologies, a great wealth of variation data is being produced. Such information may constitute the basis for correlation analyses between genotypes and phenotypes and, in the future, for personalized medicine. Several databases on gene variation exist, but this kind of information is still scarce in the Semantic Web framework. In this paper, we discuss issues related to the integration of mutation data in the Linked Open Data infrastructure, part of the Semantic Web framework. We present the development of a mapping from the IARC TP53 Mutation database to RDF and the implementation of servers publishing this data. Methods A version of the IARC TP53 Mutation database implemented in a relational database was used as first test set. Automatic mappings to RDF were first created by using D2RQ and later manually refined by introducing concepts and properties from domain vocabularies and ontologies, as well as links to Linked Open Data implementations of various systems of biomedical interest. Since D2RQ query performances are lower than those that can be achieved by using an RDF archive, generated data was also loaded into a dedicated system based on tools from the Jena software suite. Results We have implemented a D2RQ Server for TP53 mutation data, providing data on a subset of the IARC database, including gene variations, somatic mutations, and bibliographic references. The server allows to browse the RDF graph by using links both between classes and to external systems. An alternative interface offers improved performances for SPARQL queries. The resulting data can be explored by using any Semantic Web browser or application. Conclusions This has been the first case of a mutation database exposed as Linked Data. A revised version of our prototype, including further concepts and IARC TP53 Mutation database data sets, is under development. The publication of variation information as Linked Data opens new perspectives

  12. Towards linked open gene mutations data.

    Science.gov (United States)

    Zappa, Achille; Splendiani, Andrea; Romano, Paolo

    2012-03-28

    With the advent of high-throughput technologies, a great wealth of variation data is being produced. Such information may constitute the basis for correlation analyses between genotypes and phenotypes and, in the future, for personalized medicine. Several databases on gene variation exist, but this kind of information is still scarce in the Semantic Web framework. In this paper, we discuss issues related to the integration of mutation data in the Linked Open Data infrastructure, part of the Semantic Web framework. We present the development of a mapping from the IARC TP53 Mutation database to RDF and the implementation of servers publishing this data. A version of the IARC TP53 Mutation database implemented in a relational database was used as first test set. Automatic mappings to RDF were first created by using D2RQ and later manually refined by introducing concepts and properties from domain vocabularies and ontologies, as well as links to Linked Open Data implementations of various systems of biomedical interest. Since D2RQ query performances are lower than those that can be achieved by using an RDF archive, generated data was also loaded into a dedicated system based on tools from the Jena software suite. We have implemented a D2RQ Server for TP53 mutation data, providing data on a subset of the IARC database, including gene variations, somatic mutations, and bibliographic references. The server allows to browse the RDF graph by using links both between classes and to external systems. An alternative interface offers improved performances for SPARQL queries. The resulting data can be explored by using any Semantic Web browser or application. This has been the first case of a mutation database exposed as Linked Data. A revised version of our prototype, including further concepts and IARC TP53 Mutation database data sets, is under development.The publication of variation information as Linked Data opens new perspectives: the exploitation of SPARQL searches on

  13. HDAPD: a web tool for searching the disease-associated protein structures

    Science.gov (United States)

    2010-01-01

    Background The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until now, proteins structures are usually searched through a PDB id or some sequence information. However, in the HDAPD database presented here the protein structure of a disease-associated protein can be directly searched through the associated disease name keyed in. Description The search in HDAPD can be easily initiated by keying some key words of a disease, protein name, protein type, or PDB id. The protein sequence can be presented in FASTA format and directly copied for a BLAST search. HDAPD is also interfaced with Jmol so that users can observe and operate a protein structure with Jmol. The gene ontological data such as cellular components, molecular functions, and biological processes are provided once a hyperlink to Gene Ontology (GO) is clicked. Further, HDAPD provides a link to the KEGG map such that where the protein is placed and its relationship with other proteins in a metabolic pathway can be found from the map. The latest literatures namely titles, journals, authors, and abstracts searched from PubMed for the protein are also presented as a length controllable list. Conclusions Since the HDAPD data content can be routinely updated through a PHP-MySQL web page built, the new database presented is useful for searching the structures for some disease-associated proteins that may play important roles in the disease developing process for performing the structure-based drug design to against the diseases. PMID:20158919

  14. Crossing simple resonances

    International Nuclear Information System (INIS)

    Collins, T.

    1985-08-01

    A simple criterion governs the beam distortion and/or loss of protons on a fast resonance crossing. Results from numerical integrations are illustrated for simple sextupole, octupole, and 10-pole resonances

  15. Crossing simple resonances

    Energy Technology Data Exchange (ETDEWEB)

    Collins, T.

    1985-08-01

    A simple criterion governs the beam distortion and/or loss of protons on a fast resonance crossing. Results from numerical integrations are illustrated for simple sextupole, octupole, and 10-pole resonances.

  16. A simple strategy for jumping straight up.

    Science.gov (United States)

    Hemami, Hooshang; Wyman, Bostwick F

    2012-05-01

    Jumping from a stationary standing position into the air is a transition from a constrained motion in contact with the ground to an unconstrained system not in contact with the ground. A simple case of the jump, as it applies to humans, robots and humanoids, is studied in this paper. The dynamics of the constrained rigid body are expanded to define a larger system that accommodates the jump. The formulation is applied to a four-link, three-dimensional system in order to articulate the ballistic motion involved. The activity of the muscular system and the role of the major sagittal muscle groups are demonstrated. The control strategy, involving state feedback and central feed forward signals, is formulated and computer simulations are presented to assess the feasibility of the formulations, the strategy and the jump. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. Design of an Interface for Page Rank Calculation using Web Link Attributes Information

    Directory of Open Access Journals (Sweden)

    Jeyalatha SIVARAMAKRISHNAN

    2010-01-01

    Full Text Available This paper deals with the Web Structure Mining and the different Structure Mining Algorithms like Page Rank, HITS, Trust Rank and Sel-HITS. The functioning of these algorithms are discussed. An incremental algorithm for calculation of PageRank using an interface has been formulated. This algorithm makes use of Web Link Attributes Information as key parameters and has been implemented using Visibility and Position of a Link. The application of Web Structure Mining Algorithm in an Academic Search Application has been discussed. The present work can be a useful input to Web Users, Faculty, Students and Web Administrators in a University Environment.

  18. Market Dominance and Search Quality in the Search Engine Market

    NARCIS (Netherlands)

    Lianos, I.; Motchenkova, E.I.

    2013-01-01

    We analyze a search engine market from a law and economics perspective and incorporate the choice of quality-improving innovations by a search engine platform in a two-sided model of Internet search engine. In the proposed framework, we first discuss the legal issues the search engine market raises

  19. Motivation and short-term memory in visual search: Attention's accelerator revisited.

    Science.gov (United States)

    Schneider, Daniel; Bonmassar, Claudia; Hickey, Clayton

    2018-05-01

    A cue indicating the possibility of cash reward will cause participants to perform memory-based visual search more efficiently. A recent study has suggested that this performance benefit might reflect the use of multiple memory systems: when needed, participants may maintain the to-be-remembered object in both long-term and short-term visual memory, with this redundancy benefitting target identification during search (Reinhart, McClenahan & Woodman, 2016). Here we test this compelling hypothesis. We had participants complete a memory-based visual search task involving a reward cue that either preceded presentation of the to-be-remembered target (pre-cue) or followed it (retro-cue). Following earlier work, we tracked memory representation using two components of the event-related potential (ERP): the contralateral delay activity (CDA), reflecting short-term visual memory, and the anterior P170, reflecting long-term storage. We additionally tracked attentional preparation and deployment in the contingent negative variation (CNV) and N2pc, respectively. Results show that only the reward pre-cue impacted our ERP indices of memory. However, both types of cue elicited a robust CNV, reflecting an influence on task preparation, both had equivalent impact on deployment of attention to the target, as indexed in the N2pc, and both had equivalent impact on visual search behavior. Reward prospect thus has an influence on memory-guided visual search, but this does not appear to be necessarily mediated by a change in the visual memory representations indexed by CDA. Our results demonstrate that the impact of motivation on search is not a simple product of improved memory for target templates. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Tracking search engine queries for suicide in the United Kingdom, 2004-2013.

    Science.gov (United States)

    Arora, V S; Stuckler, D; McKee, M

    2016-08-01

    First, to determine if a cyclical trend is observed for search activity of suicide and three common suicide risk factors in the United Kingdom: depression, unemployment, and marital strain. Second, to test the validity of suicide search data as a potential marker of suicide risk by evaluating whether web searches for suicide associate with suicide rates among those of different ages and genders in the United Kingdom. Cross-sectional. Search engine data was obtained from Google Trends, a publicly available repository of information of trends and patterns of user searches on Google. The following phrases were entered into Google Trends to analyse relative search volume for suicide, depression, job loss, and divorce, respectively: 'suicide'; 'depression + depressed + hopeless'; 'unemployed + lost job'; 'divorce'. Spearman's rank correlation coefficient was employed to test bivariate associations between suicide search activity and official suicide rates from the Office of National Statistics (ONS). Cyclical trends were observed in search activity for suicide and depression-related search activity, with peaks in autumn and winter months, and a trough in summer months. A positive, non-significant association was found between suicide-related search activity and suicide rates in the general working-age population (15-64 years) (ρ = 0.164; P = 0.652). This association is stronger in younger age groups, particularly for those 25-34 years of age (ρ = 0.848; P = 0.002). We give credence to a link between search activity for suicide and suicide rates in the United Kingdom from 2004 to 2013 for high risk sub-populations (i.e. male youth and young professionals). There remains a need for further research on how Google Trends can be used in other areas of disease surveillance and for work to provide greater geographical precision, as well as research on ways of mitigating the risk of internet use leading to suicide ideation in youth. Copyright © 2015 The Royal

  1. Seed-mediated synthesis of cross-linked Pt-NiO nanochains for methanol oxidation

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Zhulan; Bin, Duan; Feng, Yue; Zhang, Ke; Wang, Jin; Yan, Bo; Li, Shumin; Xiong, Zhiping; Wang, Caiqin; Shiraishi, Yukihide; Du, Yukou, E-mail: duyk@suda.edu.cn

    2017-07-31

    Highlights: • Cross-linked Pt-NiO nanochains using seed-mediated growth method are synthesized. • The as-prepared catalysts exhibit higher electrocatalytic activity than Pt/C for MOR. • The Pt-NiO(1:1 by molar) catalyst shows the best electrocatalytic property towards MOR. - Abstract: A simple method was reported for employing NiO nanoparticles act as seeds and then different amounts of Pt{sup 2+} were reduced on the NiO nanoparticles, forming a cross-linked Pt-NiO nanocatalysts. These as-prepared catalysts were characterized using different physical-chemical techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The results indicate that the morphology of the cross-linked Pt-NiO nanochain was successfully produced regardless of the molar ratio of Pt{sup 2+} to NiO precursors. The electrochemical characteristics of Pt-NiO nanochain catalysts were evaluated for the oxidation of methanol as a model reaction, which verify that the Pt-NiO catalysts show enhanced activity and high stability in comparison with the commercial Pt/C catalyst. The optimized ratio of Pt to NiO is 1:1, then tuned by simple adjusting the feed ratio of the precursors as well. The synthesized nanocatalysts will be found the great potential applications as electrocatalysts for fuel cells owe to their enhanced catalytic performance and long-term stability.

  2. Seed-mediated synthesis of cross-linked Pt-NiO nanochains for methanol oxidation

    International Nuclear Information System (INIS)

    Gu, Zhulan; Bin, Duan; Feng, Yue; Zhang, Ke; Wang, Jin; Yan, Bo; Li, Shumin; Xiong, Zhiping; Wang, Caiqin; Shiraishi, Yukihide; Du, Yukou

    2017-01-01

    Highlights: • Cross-linked Pt-NiO nanochains using seed-mediated growth method are synthesized. • The as-prepared catalysts exhibit higher electrocatalytic activity than Pt/C for MOR. • The Pt-NiO(1:1 by molar) catalyst shows the best electrocatalytic property towards MOR. - Abstract: A simple method was reported for employing NiO nanoparticles act as seeds and then different amounts of Pt 2+ were reduced on the NiO nanoparticles, forming a cross-linked Pt-NiO nanocatalysts. These as-prepared catalysts were characterized using different physical-chemical techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The results indicate that the morphology of the cross-linked Pt-NiO nanochain was successfully produced regardless of the molar ratio of Pt 2+ to NiO precursors. The electrochemical characteristics of Pt-NiO nanochain catalysts were evaluated for the oxidation of methanol as a model reaction, which verify that the Pt-NiO catalysts show enhanced activity and high stability in comparison with the commercial Pt/C catalyst. The optimized ratio of Pt to NiO is 1:1, then tuned by simple adjusting the feed ratio of the precursors as well. The synthesized nanocatalysts will be found the great potential applications as electrocatalysts for fuel cells owe to their enhanced catalytic performance and long-term stability.

  3. Seed-mediated synthesis of cross-linked Pt-NiO nanochains for methanol oxidation

    Science.gov (United States)

    Gu, Zhulan; Bin, Duan; Feng, Yue; Zhang, Ke; Wang, Jin; Yan, Bo; Li, Shumin; Xiong, Zhiping; Wang, Caiqin; Shiraishi, Yukihide; Du, Yukou

    2017-07-01

    A simple method was reported for employing NiO nanoparticles act as seeds and then different amounts of Pt2+ were reduced on the NiO nanoparticles, forming a cross-linked Pt-NiO nanocatalysts. These as-prepared catalysts were characterized using different physical-chemical techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The results indicate that the morphology of the cross-linked Pt-NiO nanochain was successfully produced regardless of the molar ratio of Pt2+ to NiO precursors. The electrochemical characteristics of Pt-NiO nanochain catalysts were evaluated for the oxidation of methanol as a model reaction, which verify that the Pt-NiO catalysts show enhanced activity and high stability in comparison with the commercial Pt/C catalyst. The optimized ratio of Pt to NiO is 1:1, then tuned by simple adjusting the feed ratio of the precursors as well. The synthesized nanocatalysts will be found the great potential applications as electrocatalysts for fuel cells owe to their enhanced catalytic performance and long-term stability.

  4. Large Neighborhood Search

    DEFF Research Database (Denmark)

    Pisinger, David; Røpke, Stefan

    2010-01-01

    Heuristics based on large neighborhood search have recently shown outstanding results in solving various transportation and scheduling problems. Large neighborhood search methods explore a complex neighborhood by use of heuristics. Using large neighborhoods makes it possible to find better...... candidate solutions in each iteration and hence traverse a more promising search path. Starting from the large neighborhood search method,we give an overview of very large scale neighborhood search methods and discuss recent variants and extensions like variable depth search and adaptive large neighborhood...

  5. Dyniqx: a novel meta-search engine for metadata based cross search

    OpenAIRE

    Zhu, Jianhan; Song, Dawei; Eisenstadt, Marc; Barladeanu, Cristi; Rüger, Stefan

    2008-01-01

    The effect of metadata in collection fusion has not been sufficiently studied. In response to this, we present a novel meta-search engine called Dyniqx for metadata based cross search. Dyniqx exploits the availability of metadata in academic search services such as PubMed and Google Scholar etc for fusing search results from heterogeneous search engines. In addition, metadata from these search engines are used for generating dynamic query controls such as sliders and tick boxes etc which are ...

  6. An improved harmony search algorithm for synchronization of discrete-time chaotic systems

    International Nuclear Information System (INIS)

    Santos Coelho, Leandro dos; Andrade Bernert, Diego Luis de

    2009-01-01

    The harmony search (HS) algorithm is a recently developed meta-heuristic algorithm, and has been very successful in a wide variety of optimization problems. HS was conceptualized using an analogy with music improvisation process where music players improvise the pitches of their instruments to obtain better harmony. The HS algorithm does not require initial values and uses a random search instead of a gradient search, so derivative information is unnecessary. Furthermore, the HS algorithm is simple in concept, few in parameters, easy in implementation, imposes fewer mathematical requirements, and does not require initial value settings of the decision variables. In recent years, the investigation of synchronization and control problem for discrete chaotic systems has attracted much attention, and many possible applications. The tuning of a proportional-integral-derivative (PID) controller based on an improved HS (IHS) algorithm for synchronization of two identical discrete chaotic systems subject the different initial conditions is investigated in this paper. Simulation results of the IHS to determine the PID parameters to synchronization of two Henon chaotic systems are compared with other HS approaches including classical HS and global-best HS. Numerical results reveal that the proposed IHS method is a powerful search and controller design optimization tool for synchronization of chaotic systems.

  7. Design of Neutral-Point Voltage Controller of a Three-level NPC Inverter with Small DC-Link Capacitors

    DEFF Research Database (Denmark)

    Maheshwari, Ram Krishan; Munk-Nielsen, Stig; Busquets-Monge, S.

    2013-01-01

    A Neutral-Point-Clamped (NPC) three-level inverter with small dc-link capacitors is presented in this paper. The inverter requires zero average neutral-point current for stable neutral-point voltage. The small dc-link capacitors may not maintain capacitor voltage balance, even with zero neutral......-point voltage control on the basis of the continuous model. The design method for optimum performance is discussed. The implementation of the proposed modulation strategy and the controller is very simple. The controller is implemented in a 7.5 kW induction machine based drive with only 14 ìF dc-link capacitors...

  8. Fully automated pipeline for detection of sex linked genes using RNA-Seq data.

    Science.gov (United States)

    Michalovova, Monika; Kubat, Zdenek; Hobza, Roman; Vyskot, Boris; Kejnovsky, Eduard

    2015-03-11

    Sex chromosomes present a genomic region which to some extent, differs between the genders of a single species. Reliable high-throughput methods for detection of sex chromosomes specific markers are needed, especially in species where genome information is limited. Next generation sequencing (NGS) opens the door for identification of unique sequences or searching for nucleotide polymorphisms between datasets. A combination of classical genetic segregation analysis along with RNA-Seq data can present an ideal tool to map and identify sex chromosome-specific expressed markers. To address this challenge, we established genetic cross of dioecious plant Rumex acetosa and generated RNA-Seq data from both parental generation and male and female offspring. We present a pipeline for detection of sex linked genes based on nucleotide polymorphism analysis. In our approach, tracking of nucleotide polymorphisms is carried out using a cross of preferably distant populations. For this reason, only 4 datasets are needed - reads from high-throughput sequencing platforms for parent generation (mother and father) and F1 generation (male and female progeny). Our pipeline uses custom scripts together with external assembly, mapping and variant calling software. Given the resource-intensive nature of the computation, servers with high capacity are a requirement. Therefore, in order to keep this pipeline easily accessible and reproducible, we implemented it in Galaxy - an open, web-based platform for data-intensive biomedical research. Our tools are present in the Galaxy Tool Shed, from which they can be installed to any local Galaxy instance. As an output of the pipeline, user gets a FASTA file with candidate transcriptionally active sex-linked genes, sorted by their relevance. At the same time, a BAM file with identified genes and alignment of reads is also provided. Thus, polymorphisms following segregation pattern can be easily visualized, which significantly enhances primer design

  9. Signatures of active and passive optimized Lévy searching in jellyfish.

    Science.gov (United States)

    Reynolds, Andy M

    2014-10-06

    the result of selection pressures for advantageous searching behaviour but can instead arise freely and naturally from simple processes. It also shows that the family of Lévy walkers is vastly larger than previously thought and includes spores, pollens, seeds and minute wingless arthropods that on warm days disperse passively within the atmospheric boundary layer. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  10. Explicit awareness supports conditional visual search in the retrieval guidance paradigm.

    Science.gov (United States)

    Buttaccio, Daniel R; Lange, Nicholas D; Hahn, Sowon; Thomas, Rick P

    2014-01-01

    hypothesis generation (HyGene; Thomas, Dougherty, Sprenger, & Harbison, 2008), linking attention with long-term and working memory, accounts for the present results and provides a useful framework of cued recall visual search. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. Experimental Searches for Exotic Short-Range Forces Using Mechanical Oscillators

    Science.gov (United States)

    Weisman, Evan

    Experimental searches for forces beyond gravity and electromagnetism at short range have attracted a great deal of attention over the last decade. In this thesis I describe the test mass development for two new experiments searching for forces below 1 mm. Both modify a previous experiment that used 1 kHz mechanical oscillators as test masses with a stiff conducting shield between them to suppress backgrounds, a promising technique for probing exceptionally small distances at the limit of instrumental thermal noise. To further reduce thermal noise, one experiment will use plated silicon test masses at cryogenic temperatures. The other experiment, which searches for spin-dependent interactions, will apply the spin-polarizable material Dy3Fe5O 12 to the test mass surfaces. This material exhibits orbital compensation of the magnetism associated with its intrinsic electron spin, minimizing magnetic backgrounds. Several plated silicon test mass prototypes were fabricated using photolithography (useful in both experiments), and spin-dependent materials were synthesized with a simple chemical recipe. Both silicon and spin-dependent test masses demonstrate the mechanical and magnetic properties necessary for sensitive experiments. I also describe sensitivity calculations of another proposed spin-dependent experiment, based on a modified search for the electron electric dipole moment, which show unprecedented sensitivity to exotic monopole-dipole forces. Inspired by a finite element model, a study attempting to maximize detector quality factor versus geometry is also presented, with experimental results so far not explained by the model.

  12. Fulltext PDF

    Indian Academy of Sciences (India)

    plagiarism, or indirectly by not giving proper credit to the original source. Take any topic and a simple search on Google will give you a large number of links to scholarly articles. One should ... And it occurs at the highest levels of science, from ...

  13. Meta Search Engines.

    Science.gov (United States)

    Garman, Nancy

    1999-01-01

    Describes common options and features to consider in evaluating which meta search engine will best meet a searcher's needs. Discusses number and names of engines searched; other sources and specialty engines; search queries; other search options; and results options. (AEF)

  14. The linking number and the writhe of uniform random walks and polygons in confined spaces

    International Nuclear Information System (INIS)

    Panagiotou, E; Lambropoulou, S; Millett, K C

    2010-01-01

    Random walks and polygons are used to model polymers. In this paper we consider the extension of the writhe, self-linking number and linking number to open chains. We then study the average writhe, self-linking and linking number of random walks and polygons over the space of configurations as a function of their length. We show that the mean squared linking number, the mean squared writhe and the mean squared self-linking number of oriented uniform random walks or polygons of length n, in a convex confined space, are of the form O(n 2 ). Moreover, for a fixed simple closed curve in a convex confined space, we prove that the mean absolute value of the linking number between this curve and a uniform random walk or polygon of n edges is of the form O(√n). Our numerical studies confirm those results. They also indicate that the mean absolute linking number between any two oriented uniform random walks or polygons, of n edges each, is of the form O(n). Equilateral random walks and polygons are used to model polymers in θ-conditions. We use numerical simulations to investigate how the self-linking and linking number of equilateral random walks scale with their length.

  15. Dal record al dato. Linked data e ricerca dell’informazione nell’OPAC.

    Directory of Open Access Journals (Sweden)

    Antonella Iacono

    2013-12-01

    In this paper the author explores the possibility the new record deconstructed and connected with the other data on the Web is able to facilitate the creation of knowledge in the use of the catalogue. The author then analyzes the potential of application of linked data to the catalogue with regards to the capabilities for research, the new possibilities of semantic search and the ways to access bibliographic data.

  16. An up-link power control for demand assignment International Business Satellite Communications Network

    Science.gov (United States)

    Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio

    Up-link power control (UPC) is one of the essential technologies to provide efficient satellite communication systems operated at frequency bands above 10 GHz. A simple and cost-effective UPC scheme applicable to a demand assignment international business satellite communications system has been developed. This paper presents the UPC scheme, including the hardware implementation and its performance.

  17. Lightning rod: a simple and low cost experiment for eletrostatics

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Laburú

    2008-09-01

    Full Text Available With the objective of contributing to make significant the scientific learning, this work suggests a simple and low-cost experiment to demonstrate electrostatics knowledge studied in High School. The experimental proposal has yet the concern of focusing the content, linking it to daily technological elements. Doing that, and due to the practical interest it can arouse in student, we presented the operation of an idealized Lightning Rod to apply in electrostatics school knowledge and to show that the same one can have an important day by day usefulness and it cannot be a turned off abstraction or distant from the reality.

  18. Faceted Search

    CERN Document Server

    Tunkelang, Daniel

    2009-01-01

    We live in an information age that requires us, more than ever, to represent, access, and use information. Over the last several decades, we have developed a modern science and technology for information retrieval, relentlessly pursuing the vision of a "memex" that Vannevar Bush proposed in his seminal article, "As We May Think." Faceted search plays a key role in this program. Faceted search addresses weaknesses of conventional search approaches and has emerged as a foundation for interactive information retrieval. User studies demonstrate that faceted search provides more

  19. Beyond the search surface: visual search and attentional engagement.

    Science.gov (United States)

    Duncan, J; Humphreys, G

    1992-05-01

    Treisman (1991) described a series of visual search studies testing feature integration theory against an alternative (Duncan & Humphreys, 1989) in which feature and conjunction search are basically similar. Here the latter account is noted to have 2 distinct levels: (a) a summary of search findings in terms of stimulus similarities, and (b) a theory of how visual attention is brought to bear on relevant objects. Working at the 1st level, Treisman found that even when similarities were calibrated and controlled, conjunction search was much harder than feature search. The theory, however, can only really be tested at the 2nd level, because the 1st is an approximation. An account of the findings is developed at the 2nd level, based on the 2 processes of input-template matching and spreading suppression. New data show that, when both of these factors are controlled, feature and conjunction search are equally difficult. Possibilities for unification of the alternative views are considered.

  20. Search costs and efficiency : Do unemployed workers search enough?

    NARCIS (Netherlands)

    Gautier, Pieter A.; Moraga González, José; Wolthoff, Ronald P.

    Many labor market policies affect the marginal benefits and costs of job search. The impact and desirability of such policies depend on the distribution of search costs. In this paper, we provide an equilibrium framework for identifying the distribution of search costs and we apply it to the Dutch

  1. The application of foraging theory to the information searching behaviour of general practitioners.

    Science.gov (United States)

    Dwairy, Mai; Dowell, Anthony C; Stahl, Jean-Claude

    2011-08-23

    General Practitioners (GPs) employ strategies to identify and retrieve medical evidence for clinical decision making which take workload and time constraints into account. Optimal Foraging Theory (OFT) initially developed to study animal foraging for food is used to explore the information searching behaviour of General Practitioners. This study is the first to apply foraging theory within this context.Study objectives were: 1. To identify the sequence and steps deployed in identifiying and retrieving evidence for clinical decision making. 2. To utilise Optimal Foraging Theory to assess the effectiveness and efficiency of General Practitioner information searching. GPs from the Wellington region of New Zealand were asked to document in a pre-formatted logbook the steps and outcomes of an information search linked to their clinical decision making, and fill in a questionnaire about their personal, practice and information-searching backgrounds. A total of 115/155 eligible GPs returned a background questionnaire, and 71 completed their information search logbook. GPs spent an average of 17.7 minutes addressing their search for clinical information. Their preferred information sources were discussions with colleagues (38% of sources) and books (22%). These were the two most profitable information foraging sources (15.9 min and 9.5 min search time per answer, compared to 34.3 minutes in databases). GPs nearly always accessed another source when unsuccessful (95% after 1st source), and frequently when successful (43% after 2nd source). Use of multiple sources accounted for 41% of searches, and increased search success from 70% to 89%. By consulting in foraging terms the most 'profitable' sources of information (colleagues, books), rapidly switching sources when unsuccessful, and frequently double checking, GPs achieve an efficient trade-off between maximizing search success and information reliability, and minimizing searching time. As predicted by foraging theory, GPs

  2. GOKaRT: Graphical Online Search Tool for Maps

    Directory of Open Access Journals (Sweden)

    Mechthild Schüler

    2008-09-01

    Full Text Available The map department of the Staats- und Universitätsbibliothek Göttingen together with the Berlin State Library propose a project to develop a web-based graphic cataloguing and search system for maps, to be funded by the German Research Foundation. This tool shall be made available to all map holdings in archives, libraries, university departments and museums in Germany as a comfortable means for the administration of map holdings and as a search tool. Sheets belonging to map series as well as single maps (old and new will be registered cooperatively by the participants with simple tools. This cooperation in data maintenance will facilitate the work especially for understaffed map holdings. Depending on the type of map there are four different mechanisms for map reference. For map series electronic index sheets are used which will show information regarding the various issues of the map sheets. Due to the intuitive graphic search entry GOKaRT-users will easily find the required maps of a certain region available in a chosen holding. User administration modules ensure comfortable handling. GOKaRT is being developed on the basis of licence-free open source programmes. In case financing is provided by the German Research Foundation, GOKaRT can be used free of charge internationally. This would require a contract stipulating data exchange between the partners as well as permanent storage and usability of the data.

  3. A search for refraction in the Kepler gas giant data set

    Science.gov (United States)

    Sheets, Holly A.; Jacob, Laurent; Cowan, Nicolas; Deming, Drake

    2018-06-01

    I present the results of our systematic search for refraction in the atmospheres of giant planets in the Kepler data set. We chose our candidates using the approximations of Sidis and Sari (ApJ, 2010, 720, 904S), selecting those that had an expected signal greater than 10 parts per million. We model the refraction shoulders as simple exponentials outside of transit and fit a transit+shoulder model to individual candidates. We find that the effect is not present to the extent predicted from the approximations.

  4. A 10 Mbyte/s fiber optic link

    International Nuclear Information System (INIS)

    Brodier-Yourstone, P.; McCulloch, L.; McLaren, R.A.

    1995-01-01

    This paper presents a fiber optic link (FOL) that has been developed for the NA48 experiment at CERN. About 15 FOLs will be used to transfer event data to the Data Merger (event builder) over a distance of 200 meters. The FOL has a very simple interface and is capable of transmitting data at a rate of over 10 Mbyte/s while performing error detection. The optical part of the FOL uses industry standard components. This, combined with its simplicity of use, makes the FOL suitable to be reused in a wide range of applications, which is shown by its use outside the NA48 experiment

  5. How doctors search

    DEFF Research Database (Denmark)

    Lykke, Marianne; Price, Susan; Delcambre, Lois

    2012-01-01

    Professional, workplace searching is different from general searching, because it is typically limited to specific facets and targeted to a single answer. We have developed the semantic component (SC) model, which is a search feature that allows searchers to structure and specify the search to co...

  6. Web Search Engines

    OpenAIRE

    Rajashekar, TB

    1998-01-01

    The World Wide Web is emerging as an all-in-one information source. Tools for searching Web-based information include search engines, subject directories and meta search tools. We take a look at key features of these tools and suggest practical hints for effective Web searching.

  7. Effect of Mental State on the Rate of Identifying the Relevancy of Documents Retrieved in a Search

    Directory of Open Access Journals (Sweden)

    Faezeh Farhoudi

    2009-07-01

    Full Text Available The present study investigates the link between various users’ mental state while searching information systems with the outcome of the resulting documents retrieved. Various factors such as user knowledge, search skills, motivation and aims influence the decisions and evaluation of users regarding documents retrieved. MMPI instrument was used to identify users’ mental states. The sample was drawn from female senior students of librarianship, using systematic random sampling. The findings indicated that anxiety and depression have significant inverse relationship to the rate of relevancy identification of the documents retrieved by the users.

  8. Evolution of optimal Lévy-flight strategies in human mental searches

    Science.gov (United States)

    Radicchi, Filippo; Baronchelli, Andrea

    2012-06-01

    Recent analysis of empirical data [Radicchi, Baronchelli, and Amaral, PloS ONE1932-620310.1371/journal.pone.0029910 7, e029910 (2012)] showed that humans adopt Lévy-flight strategies when exploring the bid space in online auctions. A game theoretical model proved that the observed Lévy exponents are nearly optimal, being close to the exponent value that guarantees the maximal economical return to players. Here, we rationalize these findings by adopting an evolutionary perspective. We show that a simple evolutionary process is able to account for the empirical measurements with the only assumption that the reproductive fitness of the players is proportional to their search ability. Contrary to previous modeling, our approach describes the emergence of the observed exponent without resorting to any strong assumptions on the initial searching strategies. Our results generalize earlier research, and open novel questions in cognitive, behavioral, and evolutionary sciences.

  9. Asymptotic Performance Analysis of the k-th Best Link Selection over Wireless Fading Channels: An Extreme Value Theory Approach

    KAUST Repository

    Al-Badarneh, Yazan Hussein

    2018-01-25

    We consider a general selection-diversity (SD) scheme in which the k-th best link is selected from a number of links. We use extreme value theory (EVT) to derive simple closed-form asymptotic expressions for the average throughput, effective throughput and average bit error probability (BEP) for the k-th best link over various channel models that are widely used to characterize fading in wireless communication systems. As an application example, we consider the Weibull fading channel model and verify the accuracy of the derived asymptotic expressions through Monte Carlo simulations.

  10. Asymptotic Performance Analysis of the k-th Best Link Selection over Wireless Fading Channels: An Extreme Value Theory Approach

    KAUST Repository

    Al-Badarneh, Yazan Hussein; Georghiades, Costas; Alouini, Mohamed-Slim

    2018-01-01

    We consider a general selection-diversity (SD) scheme in which the k-th best link is selected from a number of links. We use extreme value theory (EVT) to derive simple closed-form asymptotic expressions for the average throughput, effective throughput and average bit error probability (BEP) for the k-th best link over various channel models that are widely used to characterize fading in wireless communication systems. As an application example, we consider the Weibull fading channel model and verify the accuracy of the derived asymptotic expressions through Monte Carlo simulations.

  11. Signal Region Optimisation Studies Based on BDT and Multi-Bin Approaches in the Context of Supersymmetry Searches in Hadronic Final States with the ATLAS Detector

    CERN Document Server

    AUTHOR|(CDS)2097636; Makovec, Nikola; Rúriková, Zuzana

    The searches for supersymmetric phenomena are mostly based on simple Cut & Count methods. One example is the search for squarks and gluinos in final states with multiple jets, missing transverse momentum and without leptons. This analysis, based on $36.1\\,\\text{fb}^{−1}$ of $pp$ collision data at $\\sqrt{s}$ = 13 TeV recorded with the ATLAS detector, uses Cut & Count based methods in the signal regions. In order to improve the analysis sensitivity, the use of sophisticated techniques, such as boosted decision trees (BDT) and Multi-Bin, is being investigated in this thesis. The focus of the study lies on squarks and gluino searches. These techniques are evaluated using Monte Carlo simulation. The goal is to find a new approach which is on the one hand simple but allows for a significant improvement. A gain up to approximately 200 GeV in the neutralino mass and an enhancement of about 200 GeV in the squark and gluino mass is achieved with these new techniques.

  12. Exploring Alternative Characteristic Curve Approaches to Linking Parameter Estimates from the Generalized Partial Credit Model.

    Science.gov (United States)

    Roberts, James S.; Bao, Han; Huang, Chun-Wei; Gagne, Phill

    Characteristic curve approaches for linking parameters from the generalized partial credit model were examined for cases in which common (anchor) items are calibrated separately in two groups. Three of these approaches are simple extensions of the test characteristic curve (TCC), item characteristic curve (ICC), and operating characteristic curve…

  13. Searching for Amino Acids in Meteorites and Comet Samples

    Science.gov (United States)

    Cook, Jamie Elsila

    2010-01-01

    Chemistry plays an important role in the interdisciplinary field of astrobiology, which strives to understand the origin, distribution, and evolution of life throughout the universe. Chemical techniques are used to search for and characterize the basic ingredients for life, from the elements through simple molecules and up to the more complex compounds that may serve as the ingredients for life. The Astrobiology Analytical Laboratory at NASA Goddard uses state-of-the-art laboratory analytical instrumentation in unconventional ways to examine extraterrestrial materials and tackle some of the big questions in astrobiology. This talk will discuss some of the instrumentation and techniques used for these unique samples, as well as some of our most interesting results. The talk will present two areas of particular interest in our laboratory: (1) the search for chiral excesses in meteoritic amino acids, which may help to explain the origin of homochirality in life on Earth; and (2) the detection of amino acids and amines in material returned by NASA's Stardust mission, which rendevouzed with a cornet and brought back cometary particles to the Earth.

  14. A multi-variate discrimination technique based on range-searching

    International Nuclear Information System (INIS)

    Carli, T.; Koblitz, B.

    2003-01-01

    We present a fast and transparent multi-variate event classification technique, called PDE-RS, which is based on sampling the signal and background densities in a multi-dimensional phase space using range-searching. The employed algorithm is presented in detail and its behaviour is studied with simple toy examples representing basic patterns of problems often encountered in High Energy Physics data analyses. In addition an example relevant for the search for instanton-induced processes in deep-inelastic scattering at HERA is discussed. For all studied examples, the new presented method performs as good as artificial Neural Networks and has furthermore the advantage to need less computation time. This allows to carefully select the best combination of observables which optimally separate the signal and background and for which the simulations describe the data best. Moreover, the systematic and statistical uncertainties can be easily evaluated. The method is therefore a powerful tool to find a small number of signal events in the large data samples expected at future particle colliders

  15. Distortion-Based Link Adaptation for Wireless Video Transmission

    Directory of Open Access Journals (Sweden)

    Andrew Nix

    2008-06-01

    Full Text Available Wireless local area networks (WLANs such as IEEE 802.11a/g utilise numerous transmission modes, each providing different throughputs and reliability levels. Most link adaptation algorithms proposed in the literature (i maximise the error-free data throughput, (ii do not take into account the content of the data stream, and (iii rely strongly on the use of ARQ. Low-latency applications, such as real-time video transmission, do not permit large numbers of retransmission. In this paper, a novel link adaptation scheme is presented that improves the quality of service (QoS for video transmission. Rather than maximising the error-free throughput, our scheme minimises the video distortion of the received sequence. With the use of simple and local rate distortion measures and end-to-end distortion models at the video encoder, the proposed scheme estimates the received video distortion at the current transmission rate, as well as on the adjacent lower and higher rates. This allows the system to select the link-speed which offers the lowest distortion and to adapt to the channel conditions. Simulation results are presented using the MPEG-4/AVC H.264 video compression standard over IEEE 802.11g. The results show that the proposed system closely follows the optimum theoretic solution.

  16. Availability and Reliability of FSO Links Estimated from Visibility

    Directory of Open Access Journals (Sweden)

    M. Tatarko

    2012-06-01

    Full Text Available This paper is focused on estimation availability and reliability of FSO systems. Shortcut FSO means Free Space Optics. It is a system which allows optical transmission between two steady points. We can say that it is a last mile communication system. It is an optical communication system, but the propagation media is air. This solution of last mile does not require expensive optical fiber and establishing of connection is very simple. But there are some drawbacks which have a bad influence of quality of services and availability of the link. Number of phenomena in the atmosphere such as scattering, absorption and turbulence cause a large variation of receiving optical power and laser beam attenuation. The influence of absorption and turbulence can be significantly reduced by an appropriate design of FSO link. But the visibility has the main influence on quality of the optical transmission channel. Thus, in typical continental area where rain, snow or fog occurs is important to know their values. This article gives a description of device for measuring weather conditions and information about estimation of availability and reliability of FSO links in Slovakia.

  17. Influence of 1,2-PB matrix cross-linking on structure and properties of selectively etched 1,2-PB-b-PDMS block copolymers

    DEFF Research Database (Denmark)

    Guo, Fengxiao; Andreasen, Jens Wenzel; Vigild, Martin Etchells

    2007-01-01

    of the cross-linked samples in toluene was converted into a degree of cross-linking following the Flory scheme; a simple relation between the Flory cross-linking degree and the fraction of consumed double bonds during the cross-linking reaction followed. The structure of the block copolymer at different stages...... of preparation was characterized by small-angle X-ray scattering (SAXS). In addition, scanning electron microscopy (SEM) gave direct images of the nanoporous polymer structure. Nanocavities are accessible to methanol, and observations of methanol uptake were combined with structural information from SAXS...

  18. Ergodic Capacity Analysis of Free-Space Optical Links with Nonzero Boresight Pointing Errors

    KAUST Repository

    Ansari, Imran Shafique

    2015-04-01

    A unified capacity analysis of a free-space optical (FSO) link that accounts for nonzero boresight pointing errors and both types of detection techniques (i.e. intensity modulation/ direct detection as well as heterodyne detection) is addressed in this work. More specifically, an exact closed-form expression for the moments of the end-to-end signal-to-noise ratio (SNR) of a single link FSO transmission system is presented in terms of well-known elementary functions. Capitalizing on these new moments expressions, we present approximate and simple closedform results for the ergodic capacity at high and low SNR regimes. All the presented results are verified via computer-based Monte-Carlo simulations.

  19. In search of new lead compounds for trypanosomiasis drug design: A protein structure-based linked-fragment approach

    Science.gov (United States)

    Verlinde, Christophe L. M. J.; Rudenko, Gabrielle; Hol, Wim G. J.

    1992-04-01

    A modular method for pursuing structure-based inhibitor design in the framework of a design cycle is presented. The approach entails four stages: (1) a design pathway is defined in the three-dimensional structure of a target protein; (2) this pathway is divided into subregions; (3) complementary building blocks, also called fragments, are designed in each subregion; complementarity is defined in terms of shape, hydrophobicity, hydrogen bond properties and electrostatics; and (4) fragments from different subregions are linked into potential lead compounds. Stages (3) and (4) are qualitatively guided by force-field calculations. In addition, the designed fragments serve as entries for retrieving existing compounds from chemical databases. This linked-fragment approach has been applied in the design of potentially selective inhibitors of triosephosphate isomerase from Trypanosoma brucei, the causative agent of sleeping sickness.

  20. Ordered Consumer Search

    OpenAIRE

    Armstrong, Mark

    2016-01-01

    The paper discusses situations in which consumers search through their options in a deliberate order, in contrast to more familiar models with random search. Topics include: network effects (consumers may be better off following the same search order as other consumers); the use of price and non-price advertising to direct search; the impact of consumers starting a new search with their previous supplier; the incentive sellers have to merge or co-locate with other sellers; and the incentive a...