WorldWideScience

Sample records for link load information

  1. Pitch link loads reduction of variable speed rotors by variable tuning frequency fluidlastic isolators

    Directory of Open Access Journals (Sweden)

    Han Dong

    2015-10-01

    Full Text Available To reduce the pitch link loads of variable speed rotors, variable tuning frequency fluidlastic isolators are proposed. This isolator utilizes the variation of centrifugal force due to the change of rotor speed to change the tuning port area ratio, which can change the tuning frequency of the isolator. A rotor model including the model of fluidlastic isolator is coupled with a fuselage model to predict the steady responses of the rotor system in forward flight. The aeroelastic analyses indicate that distinct performance improvement in pitch link load control can be achieved by the utilization of variable frequency isolators compared with the constant tuning frequency isolators. The 4/rev (per revolution pitch link load is observed to be reduced by 87.6% compared with the increase of 56.3% by the constant frequency isolator, when the rotor speed is reduced by 16.7%. The isolation ability at different rotor speeds in different flight states is investigated. To achieve overall load reduction within the whole range of rotor speed, the strategy of the variation of tuning frequency is adjusted. The results indicate that the 4/rev pitch link load within the whole rotor speed range is decreased.

  2. Role of Information Anxiety and Information Load on Processing of Prescription Drug Information Leaflets.

    Science.gov (United States)

    Bapat, Shweta S; Patel, Harshali K; Sansgiry, Sujit S

    2017-10-16

    In this study, we evaluate the role of information anxiety and information load on the intention to read information from prescription drug information leaflets (PILs). These PILs were developed based on the principals of information load and consumer information processing. This was an experimental prospective repeated measures study conducted in the United States where 360 (62% response rate) university students (>18 years old) participated. Participants were presented with a scenario followed by exposure to the three drug product information sources used to operationalize information load. The three sources were: (i) current practice; (ii) pre-existing one-page text only; and (iii) interventional one-page prototype PILs designed for the study. Information anxiety was measured as anxiety experienced by the individual when encountering information. The outcome variable of intention to read PILs was defined as the likelihood that the patient will read the information provided in the leaflets. A survey questionnaire was used to capture the data and the objectives were analyzed by performing a repeated measures MANOVA using SAS version 9.3. When compared to current practice and one-page text only leaflets, one-page PILs had significantly lower scores on information anxiety ( p information load ( p Information anxiety and information load significantly impacted intention to read ( p < 0.001). Newly developed PILs increased patient's intention to read and can help in improving the counseling services provided by pharmacists.

  3. Green IGP Link Weights for Energy-efficiency and Load-balancing in IP Backbone Networks

    OpenAIRE

    Francois, Frederic; Wang, Ning; Moessner, Klaus; Georgoulas, Stylianos; Xu, Ke

    2013-01-01

    The energy consumption of backbone networks has become a primary concern for network operators and regulators due to the pervasive deployment of wired backbone networks to meet the requirements of bandwidth-hungry applications. While traditional optimization of IGP link weights has been used in IP based load-balancing operations, in this paper we introduce a novel link weight setting algorithm, the Green Load-balancing Algorithm (GLA), which is able to jointly optimize both energy efficiency ...

  4. Quantitative microbiome profiling links gut community variation to microbial load.

    Science.gov (United States)

    Vandeputte, Doris; Kathagen, Gunter; D'hoe, Kevin; Vieira-Silva, Sara; Valles-Colomer, Mireia; Sabino, João; Wang, Jun; Tito, Raul Y; De Commer, Lindsey; Darzi, Youssef; Vermeire, Séverine; Falony, Gwen; Raes, Jeroen

    2017-11-23

    Current sequencing-based analyses of faecal microbiota quantify microbial taxa and metabolic pathways as fractions of the sample sequence library generated by each analysis. Although these relative approaches permit detection of disease-associated microbiome variation, they are limited in their ability to reveal the interplay between microbiota and host health. Comparative analyses of relative microbiome data cannot provide information about the extent or directionality of changes in taxa abundance or metabolic potential. If microbial load varies substantially between samples, relative profiling will hamper attempts to link microbiome features to quantitative data such as physiological parameters or metabolite concentrations. Saliently, relative approaches ignore the possibility that altered overall microbiota abundance itself could be a key identifier of a disease-associated ecosystem configuration. To enable genuine characterization of host-microbiota interactions, microbiome research must exchange ratios for counts. Here we build a workflow for the quantitative microbiome profiling of faecal material, through parallelization of amplicon sequencing and flow cytometric enumeration of microbial cells. We observe up to tenfold differences in the microbial loads of healthy individuals and relate this variation to enterotype differentiation. We show how microbial abundances underpin both microbiota variation between individuals and covariation with host phenotype. Quantitative profiling bypasses compositionality effects in the reconstruction of gut microbiota interaction networks and reveals that the taxonomic trade-off between Bacteroides and Prevotella is an artefact of relative microbiome analyses. Finally, we identify microbial load as a key driver of observed microbiota alterations in a cohort of patients with Crohn's disease, here associated with a low-cell-count Bacteroides enterotype (as defined through relative profiling).

  5. Allostatic Load Is Linked to Cortical Thickness Changes Depending on Body-Weight Status

    Directory of Open Access Journals (Sweden)

    Jonatan Ottino-González

    2017-12-01

    Full Text Available Objective: Overweight (body mass index or BMI ≥ 25 kg/m2 and stress interact with each other in complex ways. Overweight promotes chronic low-inflammation states, while stress is known to mediate caloric intake. Both conditions are linked to several avoidable health problems and to cognitive decline, brain atrophy, and dementia. Since it was proposed as a framework for the onset of mental illness, the allostatic load model has received increasing attention. Although changes in health and cognition related to overweight and stress are well-documented separately, the association between allostatic load and brain integrity has not been addressed in depth, especially among overweight subjects.Method: Thirty-four healthy overweight-to-obese and 29 lean adults underwent blood testing, neuropsychological examination, and magnetic resonance imaging to assess the relationship between cortical thickness and allostatic load, represented as an index of 15 biomarkers (this is, systolic and diastolic arterial tension, glycated hemoglobin, glucose, creatinine, total cholesterol, HDL and LDL cholesterol, triglycerides, c-reactive protein, interleukin-6, insulin, cortisol, fibrinogen, and leptin.Results: Allostatic load indexes showed widespread positive and negative significant correlations (p < 0.01 with cortical thickness values depending on body-weight status.Conclusion: The increase of allostatic load is linked to changes in the gray matter composition of regions monitoring behavior, sensory-reward processing, and general cognitive function.

  6. Allostatic Load Is Linked to Cortical Thickness Changes Depending on Body-Weight Status

    Science.gov (United States)

    Ottino-González, Jonatan; Jurado, María A.; García-García, Isabel; Segura, Bàrbara; Marqués-Iturria, Idoia; Sender-Palacios, María J.; Tor, Encarnació; Prats-Soteras, Xavier; Caldú, Xavier; Junqué, Carme; Garolera, Maite

    2017-01-01

    Objective: Overweight (body mass index or BMI ≥ 25 kg/m2) and stress interact with each other in complex ways. Overweight promotes chronic low-inflammation states, while stress is known to mediate caloric intake. Both conditions are linked to several avoidable health problems and to cognitive decline, brain atrophy, and dementia. Since it was proposed as a framework for the onset of mental illness, the allostatic load model has received increasing attention. Although changes in health and cognition related to overweight and stress are well-documented separately, the association between allostatic load and brain integrity has not been addressed in depth, especially among overweight subjects. Method: Thirty-four healthy overweight-to-obese and 29 lean adults underwent blood testing, neuropsychological examination, and magnetic resonance imaging to assess the relationship between cortical thickness and allostatic load, represented as an index of 15 biomarkers (this is, systolic and diastolic arterial tension, glycated hemoglobin, glucose, creatinine, total cholesterol, HDL and LDL cholesterol, triglycerides, c-reactive protein, interleukin-6, insulin, cortisol, fibrinogen, and leptin). Results: Allostatic load indexes showed widespread positive and negative significant correlations (p < 0.01) with cortical thickness values depending on body-weight status. Conclusion: The increase of allostatic load is linked to changes in the gray matter composition of regions monitoring behavior, sensory-reward processing, and general cognitive function. PMID:29375342

  7. Use of link to mammography screening information and link sharing strategies

    DEFF Research Database (Denmark)

    Mukai, Thomas; Bro, Flemming; Olesen, Frede

    2011-01-01

    -43%) reported use of the link. The difference between the two strategies was 15% (95% CI: 8-22%) (Pused the link prior to the screening event, and 37% (95% CI: 30-43%) used the link afterwards. The difference was 9% (95% CI: 0-17%) (P=0.035). Among the GPs in group 1, 40% (95% CI......Introduction: The Internet is increasingly being used for disseminating knowledge in health care. Often this is done through a ‘Uniform Resource Locator’ (URL), better known as a link. There are three ways of sharing a link: verbally, in print or electronically. Furthermore, timing and exposure...... in Central Denmark Region, we constructed a website containing screening programme information for GPs. We inserted the link to this website in different media and divided the GPs into three groups: Group 1 received a letter prior to the screening event and an electronic test result after the screening...

  8. Effect of cross-linking on properties and release characteristics of sodium salicylate-loaded electrospun poly(vinyl alcohol) fibre mats

    International Nuclear Information System (INIS)

    Taepaiboon, Pattama; Rungsardthong, Uracha; Supaphol, Pitt

    2007-01-01

    Cross-linking of electrospun (e-spun) fibre mats (beaded fibre morphology with the average diameter of the fibre segments between beads being ∼108 nm) of poly(vinyl alcohol) (PVA) containing sodium salicylate (SS), used as the model drug, was achieved by exposing the fibre mats to the vapour from 5.6 M aqueous solution of either glutaraldehyde or glyoxal for various exposure time intervals, followed by a heat treatment in a vacuum oven. With increasing the exposure time in the cross-linking chamber, the morphology of the e-spun fibre mats gradually changed from a porous to dense structure. Both the degree of swelling and the percentage of weight loss of the cross-linked fibre mats (i.e. ∼200-530% and ∼15-57%, respectively) were lower than those of the untreated ones (i.e. ∼610% and ∼67%, respectively). Cross-linking was also responsible for the monotonic increase in the storage moduli of the cross-linked SS-loaded e-spun PVA fibre mats with increasing exposure time in the cross-linking chamber. The release characteristic of the model drug from the SS-loaded e-spun PVA fibre mats both before and after cross-linking was assessed by the transdermal diffusion through a pig skin method. The cumulative release of the drug from these matrices could be divided into two stages: 0-4 and 4-72 h, in which the amount of SS released in the first stage increased very rapidly, while it was much slower in the second stage. Cross-linking slowed down the release of SS from the drug-loaded fibre mats appreciably and both the rate of release and the total amount of the drug released were decreasing functions of the exposure time interval in the cross-linking chamber. Lastly, the cross-linked SS-loaded e-spun PVA fibre mats were non-toxic to normal human dermal fibroblasts

  9. Mining Heterogeneous Information Networks by Exploring the Power of Links

    Science.gov (United States)

    Han, Jiawei

    Knowledge is power but for interrelated data, knowledge is often hidden in massive links in heterogeneous information networks. We explore the power of links at mining heterogeneous information networks with several interesting tasks, including link-based object distinction, veracity analysis, multidimensional online analytical processing of heterogeneous information networks, and rank-based clustering. Some recent results of our research that explore the crucial information hidden in links will be introduced, including (1) Distinct for object distinction analysis, (2) TruthFinder for veracity analysis, (3) Infonet-OLAP for online analytical processing of information networks, and (4) RankClus for integrated ranking-based clustering. We also discuss some of our on-going studies in this direction.

  10. Lie construction affects information storage under high memory load condition.

    Directory of Open Access Journals (Sweden)

    Yuqiu Liu

    Full Text Available Previous studies indicate that lying consumes cognitive resources, especially working memory (WM resources. Considering the dual functions that WM might play in lying: holding the truth-related information and turning the truth into lies, the present study examined the relationship between the information storage and processing in the lie construction. To achieve that goal, a deception task based on the old/new recognition paradigm was designed, which could manipulate two levels of WM load (low-load task using 4 items and high-load task using 6 items during the deception process. The analyses based on the amplitude of the contralateral delay activity (CDA, a proved index of the number of representations being held in WM, showed that the CDA amplitude was lower in the deception process than that in the truth telling process under the high-load condition. In contrast, under the low-load condition, no CDA difference was found between the deception and truth telling processes. Therefore, we deduced that the lie construction and information storage compete for WM resources; when the available WM resources cannot meet this cognitive demand, the WM resources occupied by the information storage would be consumed by the lie construction.

  11. Lie construction affects information storage under high memory load condition.

    Science.gov (United States)

    Liu, Yuqiu; Wang, Chunjie; Jiang, Haibo; He, Hongjian; Chen, Feiyan

    2017-01-01

    Previous studies indicate that lying consumes cognitive resources, especially working memory (WM) resources. Considering the dual functions that WM might play in lying: holding the truth-related information and turning the truth into lies, the present study examined the relationship between the information storage and processing in the lie construction. To achieve that goal, a deception task based on the old/new recognition paradigm was designed, which could manipulate two levels of WM load (low-load task using 4 items and high-load task using 6 items) during the deception process. The analyses based on the amplitude of the contralateral delay activity (CDA), a proved index of the number of representations being held in WM, showed that the CDA amplitude was lower in the deception process than that in the truth telling process under the high-load condition. In contrast, under the low-load condition, no CDA difference was found between the deception and truth telling processes. Therefore, we deduced that the lie construction and information storage compete for WM resources; when the available WM resources cannot meet this cognitive demand, the WM resources occupied by the information storage would be consumed by the lie construction.

  12. Research on a Method of Geographical Information Service Load Balancing

    Science.gov (United States)

    Li, Heyuan; Li, Yongxing; Xue, Zhiyong; Feng, Tao

    2018-05-01

    With the development of geographical information service technologies, how to achieve the intelligent scheduling and high concurrent access of geographical information service resources based on load balancing is a focal point of current study. This paper presents an algorithm of dynamic load balancing. In the algorithm, types of geographical information service are matched with the corresponding server group, then the RED algorithm is combined with the method of double threshold effectively to judge the load state of serve node, finally the service is scheduled based on weighted probabilistic in a certain period. At the last, an experiment system is built based on cluster server, which proves the effectiveness of the method presented in this paper.

  13. Exploiting Information Diffusion Feature for Link Prediction in Sina Weibo.

    Science.gov (United States)

    Li, Dong; Zhang, Yongchao; Xu, Zhiming; Chu, Dianhui; Li, Sheng

    2016-01-28

    The rapid development of online social networks (e.g., Twitter and Facebook) has promoted research related to social networks in which link prediction is a key problem. Although numerous attempts have been made for link prediction based on network structure, node attribute and so on, few of the current studies have considered the impact of information diffusion on link creation and prediction. This paper mainly addresses Sina Weibo, which is the largest microblog platform with Chinese characteristics, and proposes the hypothesis that information diffusion influences link creation and verifies the hypothesis based on real data analysis. We also detect an important feature from the information diffusion process, which is used to promote link prediction performance. Finally, the experimental results on Sina Weibo dataset have demonstrated the effectiveness of our methods.

  14. Exploiting Information Diffusion Feature for Link Prediction in Sina Weibo

    Science.gov (United States)

    Li, Dong; Zhang, Yongchao; Xu, Zhiming; Chu, Dianhui; Li, Sheng

    2016-01-01

    The rapid development of online social networks (e.g., Twitter and Facebook) has promoted research related to social networks in which link prediction is a key problem. Although numerous attempts have been made for link prediction based on network structure, node attribute and so on, few of the current studies have considered the impact of information diffusion on link creation and prediction. This paper mainly addresses Sina Weibo, which is the largest microblog platform with Chinese characteristics, and proposes the hypothesis that information diffusion influences link creation and verifies the hypothesis based on real data analysis. We also detect an important feature from the information diffusion process, which is used to promote link prediction performance. Finally, the experimental results on Sina Weibo dataset have demonstrated the effectiveness of our methods.

  15. Reducing the information load in map animations as a tool for exploratory analysis

    OpenAIRE

    Multimäki, Salla

    2016-01-01

    This dissertation investigates the information load that animated maps cause to their viewers, and presents two novel visualisation methods to support the exploratory visual analysis of the animations. Information load consists of the information content of the map and its presentation. The number of objects and their attributes are the unavoidable content, but the visualisation of the objects, the background map, and display settings of an animation have an effect on the information load and...

  16. Linked Data Methodologies for Managing Information about Television Content

    Directory of Open Access Journals (Sweden)

    José Luis Redondo-García

    2012-09-01

    Full Text Available OntoTV is a television information management system designed for improving the quality and quantity of the information available in the current television platforms. In order to achieve this objective, OntoTV (1 collects the information offered by the broadcasters, (2 integrates it into a ontology-based data structure, (3 extracts extra data from alternative television sources, and (4 makes possible for the user to perform queries over the stored information.This document shows the way Linked Data methodologies have been applied in OntoTV system, and the improvements in the data consumption and publication processes that have been obtained as result. On the one hand, the possibility of accessing to information available in the Web of Data has made possible to offer more complete descriptions about the programs, as well as more detailed guides than those obtained by using classic collection methods. On the other hand, as the information of the television programs and channels is published according to the Linked Data philosophy, it becomes available not only for OntoTV clients, but also for other agents able to access Linked Data resources, who could offer the viewer more fresh and innovative features.

  17. Discrimination and anger control as pathways linking socioeconomic disadvantage to allostatic load in midlife.

    Science.gov (United States)

    Zilioli, Samuele; Imami, Ledina; Ong, Anthony D; Lumley, Mark A; Gruenewald, Tara

    2017-12-01

    Recent evidence suggests that experiences of discrimination contribute to socioeconomic status health disparities. The current study examined if the experience and regulation of anger-an expected emotional response to discrimination-serves as an explanatory factor for the previously documented links between socioeconomic disadvantage (SED), discrimination, and allostatic load. Data were drawn from the second wave of the Midlife in the United States (MIDUS) study and included 909 adults who participated in the biomarkers subproject. Results revealed that perceived discrimination was associated with higher levels of allostatic load. Furthermore, we found evidence that perceived discrimination and anger control sequentially explained the relationship between SED and allostatic load, such that greater discrimination was associated with lower levels of anger control, which, in turn accounted for the effects of discrimination on allostatic load. These results remained significant after controlling for negative affect, positive affect, other forms of anger expression, as well as demographic covariates. Our findings suggest that low anger control may be an important psychological pathway through which experiences of discrimination influence health. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Is there a causal link between knee loading and knee osteoarthritis progression?

    DEFF Research Database (Denmark)

    Henriksen, Marius; Creaby, Mark W; Lund, Hans

    2014-01-01

    OBJECTIVE: We performed a systematic review, meta-analysis and assessed the evidence supporting a causal link between knee joint loading during walking and structural knee osteoarthritis (OA) progression. DESIGN: Systematic review, meta-analysis and application of Bradford Hill's considerations...... was assessed from cohort studies using the Bradford Hill guidelines to derive a 0-4 causation score based on four criteria and examined for confirmation in RCTs. RESULTS: Of the 1078 potentially eligible articles, 5 prospective cohort studies were included. The studies included a total of 452 patients relating...

  19. Damage evolution analysis of coal samples under cyclic loading based on single-link cluster method

    Science.gov (United States)

    Zhang, Zhibo; Wang, Enyuan; Li, Nan; Li, Xuelong; Wang, Xiaoran; Li, Zhonghui

    2018-05-01

    In this paper, the acoustic emission (AE) response of coal samples under cyclic loading is measured. The results show that there is good positive relation between AE parameters and stress. The AE signal of coal samples under cyclic loading exhibits an obvious Kaiser Effect. The single-link cluster (SLC) method is applied to analyze the spatial evolution characteristics of AE events and the damage evolution process of coal samples. It is found that a subset scale of the SLC structure becomes smaller and smaller when the number of cyclic loading increases, and there is a negative linear relationship between the subset scale and the degree of damage. The spatial correlation length ξ of an SLC structure is calculated. The results show that ξ fluctuates around a certain value from the second cyclic loading process to the fifth cyclic loading process, but spatial correlation length ξ clearly increases in the sixth loading process. Based on the criterion of microcrack density, the coal sample failure process is the transformation from small-scale damage to large-scale damage, which is the reason for changes in the spatial correlation length. Through a systematic analysis, the SLC method is an effective method to research the damage evolution process of coal samples under cyclic loading, and will provide important reference values for studying coal bursts.

  20. GUILD: GUidance for Information about Linking Data sets†

    Science.gov (United States)

    Gilbert, Ruth; Lafferty, Rosemary; Hagger-Johnson, Gareth; Zhang, Li-Chun; Smith, Peter; Dibben, Chris; Goldstein, Harvey

    2018-01-01

    Abstract Record linkage of administrative and survey data is increasingly used to generate evidence to inform policy and services. Although a powerful and efficient way of generating new information from existing data sets, errors related to data processing before, during and after linkage can bias results. However, researchers and users of linked data rarely have access to information that can be used to assess these biases or take them into account in analyses. As linked administrative data are increasingly used to provide evidence to guide policy and services, linkage error, which disproportionately affects disadvantaged groups, can undermine evidence for public health. We convened a group of researchers and experts from government data providers to develop guidance about the information that needs to be made available about the data linkage process, by data providers, data linkers, analysts and the researchers who write reports. The guidance goes beyond recommendations for information to be included in research reports. Our aim is to raise awareness of information that may be required at each step of the linkage pathway to improve the transparency, reproducibility, and accuracy of linkage processes, and the validity of analyses and interpretation of results. PMID:28369581

  1. Improving local clustering based top-L link prediction methods via asymmetric link clustering information

    Science.gov (United States)

    Wu, Zhihao; Lin, Youfang; Zhao, Yiji; Yan, Hongyan

    2018-02-01

    Networks can represent a wide range of complex systems, such as social, biological and technological systems. Link prediction is one of the most important problems in network analysis, and has attracted much research interest recently. Many link prediction methods have been proposed to solve this problem with various techniques. We can note that clustering information plays an important role in solving the link prediction problem. In previous literatures, we find node clustering coefficient appears frequently in many link prediction methods. However, node clustering coefficient is limited to describe the role of a common-neighbor in different local networks, because it cannot distinguish different clustering abilities of a node to different node pairs. In this paper, we shift our focus from nodes to links, and propose the concept of asymmetric link clustering (ALC) coefficient. Further, we improve three node clustering based link prediction methods via the concept of ALC. The experimental results demonstrate that ALC-based methods outperform node clustering based methods, especially achieving remarkable improvements on food web, hamster friendship and Internet networks. Besides, comparing with other methods, the performance of ALC-based methods are very stable in both globalized and personalized top-L link prediction tasks.

  2. Cognitive constraints increase estimation biases: Cognitive load and delay in judgments

    OpenAIRE

    Allred, Sarah; Crawford, L. Elizabeth; Duffy, Sean; Smith, John

    2014-01-01

    Previous work has demonstrated that memory for simple stimuli can be biased by information about the category of which the stimulus is a member. These biases have been interpreted as optimally integrating noisy sensory information with category information. A separate literature has demonstrated that cognitive load can lead to biases in social cognition. Here we link the two, asking whether delay (Experiment 1) and cognitive load (Experiment 2) affect the extent to which observers' memories f...

  3. Using Process Load Cell Information for IAEA Safeguards at Enrichment Plants

    International Nuclear Information System (INIS)

    Laughter, Mark D.; Whitaker, J. Michael; Howell, John

    2010-01-01

    Uranium enrichment service providers are expanding existing enrichment plants and constructing new facilities to meet demands resulting from the shutdown of gaseous diffusion plants, the completion of the U.S.-Russia highly enriched uranium downblending program, and the projected global renaissance in nuclear power. The International Atomic Energy Agency (IAEA) conducts verification inspections at safeguarded facilities to provide assurance that signatory States comply with their treaty obligations to use nuclear materials only for peaceful purposes. Continuous, unattended monitoring of load cells in UF 6 feed/withdrawal stations can provide safeguards-relevant process information to make existing safeguards approaches more efficient and effective and enable novel safeguards concepts such as information-driven inspections. The IAEA has indicated that process load cell monitoring will play a central role in future safeguards approaches for large-scale gas centrifuge enrichment plants. This presentation will discuss previous work and future plans related to continuous load cell monitoring, including: (1) algorithms for automated analysis of load cell data, including filtering methods to determine significant weights and eliminate irrelevant impulses; (2) development of metrics for declaration verification and off-normal operation detection ('cylinder counting,' near-real-time mass balancing, F/P/T ratios, etc.); (3) requirements to specify what potentially sensitive data is safeguards relevant, at what point the IAEA gains on-site custody of the data, and what portion of that data can be transmitted off-site; (4) authentication, secure on-site storage, and secure transmission of load cell data; (5) data processing and remote monitoring schemes to control access to sensitive and proprietary information; (6) integration of process load cell data in a layered safeguards approach with cross-check verification; (7) process mock-ups constructed to provide simulated load

  4. Length Matters: Informational Load in Ambiguity Resolution

    Directory of Open Access Journals (Sweden)

    Barbara Hemforth

    2013-07-01

    Full Text Available In this paper, we will compare prosodic and pragmatic approaches to the role of constituent length in attachment ambiguities. Lengthening a constituent affects its informativity: longer constituents are usually less predictable (Levy & Florian, 2007 and demand a higher processing load than shorter ones (Almor, 1999. Following neo-Gricean accounts (Levinson, 1987 and 1991, increased informational load needs to be justified. This justification is achieved more easily when the long constituent conveys new information and when it relates to central elements of the utterance. Informational load is, however, not a simple question of length in numbers of characters or syllables but more likely a question of amount of information. In three off-line experiments using a cloze task, we will compare the effect of lengthening ambiguous prepositional phrases as in [1a/b/c] either by lengthening a city name or by adding information about the city. We will show that only lengthening by adding information increases attachment to a more central element of the utterance. These results will be discussed based on prosodic and pragmatic factors explaining the role of constituent length for attachment ambiguities.[1] Peter met the doctor of the lawyer from a. Apt. / b. Aix-en-Provence / c. the beautiful city of Apt.Dans cet article, nous comparons une approche prosodique avec une approche pragmatique pour rendre compte des effets de la longueur des constituants dans les ambigüités d’attachement. Augmenter la longueur d’un constituant a des conséquences sur l’information qu’il véhicule : plus un constituant est long et moins il est prédictible (Levy et Florian, 2007 et plus son coût de traitement augmente (Almor, 1999. Suivant les principes néo-gricéens (Levinson, 1987 et 1991, augmenter le poids informationnel doit être justifié. Cette justification est plus facilement satisfaite lorsqu’un constituant long véhicule une information

  5. US HealthLink: a national information resource for health care professionals.

    Science.gov (United States)

    Yasnoff, W A

    1992-06-01

    US HealthLink is a new, comprehensive online medical information system designed specifically for health care professionals. Available to individuals for a fixed fee, it includes literature, news, diagnostic decision support, drug interactions, electronic mail, and bulletin boards. It also provides user-specific current awareness via clipping service, and fax delivery of both clipping and electronic mail information. US HealthLink can now be utilized to access a wide variety of medical information sources inexpensively.

  6. Linked environmental data. The next step for environmental information systems

    International Nuclear Information System (INIS)

    Menger, Matthias; Ackermann, Patrick; Linse, Andreas; Bandholtz, Thomas

    2013-01-01

    The Federal Environment Agency (UBA) in Germany as one Competent Authority of the European Member States involved with the assessment and authorisation of chemicals, pesticides, biozides and medicals, has a wide expertise of complex information systems. Having timely, comprehensive and reliable information on the environmental relevant properties (e.g. of chemical substances and preparations) is of immense importance for all sections dealing with environmental protection issues. Regarding the reality of available information systems in each environmental section, and moreover in each section itself, there has been developed several specific approaches to gather, store and search its relevant data. This makes sense due to each section has its own requirements, different user groups (industry and authorities or just authorities or scientific partners etc.), different budgets to bring technology 'on the road', and different (legally obligatory) procedures to handle the data and information of such systems. Nevertheless, there several strong reasons to look for a Linked Environmental Data infrastructure - at least internally in one authority itself: - Overcome the mostly separated systems; - Explore the potential of data silos in several environmental sections; - Efficiency/effectiveness in data gathering, assessment, results, budgets..; - sharing of knowledge, i.e. use of specific prepared information of specially intended information systems; - timelyness of data/information; - best data/information from most competent partner/section; - gain from already available systems and their data/information; - speed up developments and availability of data/information. Of course there are also several points which might be a huge obstacle to Linked Environmental Data (LED), e.g. confidential business data. This leads already to the distinction between 'Open LED' and 'Non-Open LED'. Nevertheless, the potential benefits and the possibilities offered via the modern information

  7. Geographic Information Systems using CODES linked data (Crash outcome data evaluation system)

    Science.gov (United States)

    2001-04-01

    This report presents information about geographic information systems (GIS) and CODES linked data. Section one provides an overview of a GIS and the benefits of linking to CODES. Section two outlines the basic issues relative to the types of map data...

  8. Efficient network disintegration under incomplete information: the comic effect of link prediction

    Science.gov (United States)

    Tan, Suo-Yi; Wu, Jun; Lü, Linyuan; Li, Meng-Jun; Lu, Xin

    2016-01-01

    The study of network disintegration has attracted much attention due to its wide applications, including suppressing the epidemic spreading, destabilizing terrorist network, preventing financial contagion, controlling the rumor diffusion and perturbing cancer networks. The crux of this matter is to find the critical nodes whose removal will lead to network collapse. This paper studies the disintegration of networks with incomplete link information. An effective method is proposed to find the critical nodes by the assistance of link prediction techniques. Extensive experiments in both synthetic and real networks suggest that, by using link prediction method to recover partial missing links in advance, the method can largely improve the network disintegration performance. Besides, to our surprise, we find that when the size of missing information is relatively small, our method even outperforms than the results based on complete information. We refer to this phenomenon as the “comic effect” of link prediction, which means that the network is reshaped through the addition of some links that identified by link prediction algorithms, and the reshaped network is like an exaggerated but characteristic comic of the original one, where the important parts are emphasized. PMID:26960247

  9. Efficient network disintegration under incomplete information: the comic effect of link prediction

    Science.gov (United States)

    Tan, Suo-Yi; Wu, Jun; Lü, Linyuan; Li, Meng-Jun; Lu, Xin

    2016-03-01

    The study of network disintegration has attracted much attention due to its wide applications, including suppressing the epidemic spreading, destabilizing terrorist network, preventing financial contagion, controlling the rumor diffusion and perturbing cancer networks. The crux of this matter is to find the critical nodes whose removal will lead to network collapse. This paper studies the disintegration of networks with incomplete link information. An effective method is proposed to find the critical nodes by the assistance of link prediction techniques. Extensive experiments in both synthetic and real networks suggest that, by using link prediction method to recover partial missing links in advance, the method can largely improve the network disintegration performance. Besides, to our surprise, we find that when the size of missing information is relatively small, our method even outperforms than the results based on complete information. We refer to this phenomenon as the “comic effect” of link prediction, which means that the network is reshaped through the addition of some links that identified by link prediction algorithms, and the reshaped network is like an exaggerated but characteristic comic of the original one, where the important parts are emphasized.

  10. Linked environmental data. The next step for environmental information systems

    Energy Technology Data Exchange (ETDEWEB)

    Menger, Matthias; Ackermann, Patrick; Linse, Andreas [Federal Environemnt Agency, Dessau (Germany); Bandholtz, Thomas [innoQ GmbH, Monheim (Germany)

    2013-07-01

    The Federal Environment Agency (UBA) in Germany as one Competent Authority of the European Member States involved with the assessment and authorisation of chemicals, pesticides, biozides and medicals, has a wide expertise of complex information systems. Having timely, comprehensive and reliable information on the environmental relevant properties (e.g. of chemical substances and preparations) is of immense importance for all sections dealing with environmental protection issues. Regarding the reality of available information systems in each environmental section, and moreover in each section itself, there has been developed several specific approaches to gather, store and search its relevant data. This makes sense due to each section has its own requirements, different user groups (industry and authorities or just authorities or scientific partners etc.), different budgets to bring technology 'on the road', and different (legally obligatory) procedures to handle the data and information of such systems. Nevertheless, there several strong reasons to look for a Linked Environmental Data infrastructure - at least internally in one authority itself: - Overcome the mostly separated systems; - Explore the potential of data silos in several environmental sections; - Efficiency/effectiveness in data gathering, assessment, results, budgets..; - sharing of knowledge, i.e. use of specific prepared information of specially intended information systems; - timelyness of data/information; - best data/information from most competent partner/section; - gain from already available systems and their data/information; - speed up developments and availability of data/information. Of course there are also several points which might be a huge obstacle to Linked Environmental Data (LED), e.g. confidential business data. This leads already to the distinction between 'Open LED' and 'Non-Open LED'. Nevertheless, the potential benefits and the possibilities

  11. Linking CDOM spectral absorption to dissolved organic carbon concentrations and loadings in boreal estuaries

    DEFF Research Database (Denmark)

    Asmala, Eero; Stedmon, Colin A.; Thomas, David N.

    2012-01-01

    concentrations across the salinity gradient and ranged from 1.67 to 33.4 m−1. The link between DOC and CDOM was studied using a range of wavelengths and algorithms. Wavelengths between 250 and 270 nm gave the best predictions with single linear regression. Total dissolved iron was found to influence......The quantity of chromophoric dissolved organic matter (CDOM) and dissolved organic carbon (DOC) in three Finnish estuaries (Karjaanjoki, Kyrönjoki and Kiiminkijoki) was investigated, with respect to predicting DOC concentrations and loadings from spectral CDOM absorption measurements. Altogether 87...... the prediction in wavelengths above 520nm. Despite significant seasonal and spatial differences in DOC–CDOM models, a universal relationship was tested with an independent data set and found to be robust. DOC and CDOM yields (loading/catchment area) from the catchments ranged from 1.98 to 5.44gCm−2yr−1, and 1...

  12. Is there a causal link between knee loading and knee osteoarthritis progression? A systematic review and meta-analysis of cohort studies and randomised trials

    Science.gov (United States)

    Henriksen, Marius; Creaby, Mark W; Lund, Hans; Juhl, Carsten; Christensen, Robin

    2014-01-01

    Objective We performed a systematic review, meta-analysis and assessed the evidence supporting a causal link between knee joint loading during walking and structural knee osteoarthritis (OA) progression. Design Systematic review, meta-analysis and application of Bradford Hill's considerations on causation. Data sources We searched MEDLINE, Scopus, AMED, CINAHL and SportsDiscus for prospective cohort studies and randomised controlled trials (RCTs) from 1950 through October 2013. Study eligibility criteria We selected cohort studies and RCTs in which estimates of knee joint loading during walking were used to predict structural knee OA progression assessed by X-ray or MRI. Data analyses Meta-analysis was performed to estimate the combined OR for structural disease progression with higher baseline loading. The likelihood of a causal link between knee joint loading and OA progression was assessed from cohort studies using the Bradford Hill guidelines to derive a 0–4 causation score based on four criteria and examined for confirmation in RCTs. Results Of the 1078 potentially eligible articles, 5 prospective cohort studies were included. The studies included a total of 452 patients relating joint loading to disease progression over 12–72 months. There were very serious limitations associated with the methodological quality of the included studies. The combined OR for disease progression was 1.90 (95% CI 0.85 to 4.25; I2=77%) for each one-unit increment in baseline knee loading. The combined causation score was 0, indicating no causal association between knee loading and knee OA progression. No RCTs were found to confirm or refute the findings from the cohort studies. Conclusions There is very limited and low-quality evidence to support for a causal link between knee joint loading during walking and structural progression of knee OA. Trial registration number CRD42012003253 PMID:25031196

  13. Links between attachment and social information processing: examination of intergenerational processes.

    Science.gov (United States)

    Dykas, Matthew J; Ehrlich, Katherine B; Cassidy, Jude

    2011-01-01

    This chapter describes theory and research on intergenerational connections between parents' attachment and children's social information processing, as well as between parents' social information processing and children's attachment. The chapter begins with a discussion of attachment theorists' early insights into the role that social information processing plays in attachment processes. Next, current theory about the mechanisms through which cross-generational links between attachment and social information processing might emerge is presented. The central proposition is that the quality of attachment and/or the social information processing of the parent contributes to the quality of attachment and/or social information processing in the child, and these links emerge through mediating processes related to social learning, open communication, gate-keeping, emotion regulation, and joint attention. A comprehensive review of the literature is then presented. The chapter ends with the presentation of a current theoretical perspective and suggestions for future empirical and clinical endeavors.

  14. Dynamic link: user's manual

    International Nuclear Information System (INIS)

    Harada, Hiroo; Asai, Kiyoshi; Kihara, Kazuhisa.

    1981-09-01

    The purpose of dynamic link facility is to link a load module dynamically only when it is used in execution time. The facility is very useful for development, execution and maintenance of a large scale computer program which is too big to be saved as one load module in main memory, or it is poor economy to save it due to many unused subroutines depending on an input. It is also useful for standardization and common utilization of programs. Standard usage of dynamic link facility of FACOM M-200 computer system, a software tool which analyzes the effect of dynamic link facility and application of dynamic link to nuclear codes are described. (author)

  15. Wireless Energy and Information Transmission in FSO and RF-FSO Links

    KAUST Repository

    Makki, Behrooz

    2017-09-22

    We propose and analyze a wireless energy and information transmission scheme in free-space optical (FSO) links. The results are presented for both quasi-static and fast-fading conditions. We derive closed-form expressions for throughput, outage probability and optimal power allocation optimizing the system throughput/outage probability. Finally, we complement the FSO link with an additional radio frequency (RF) link to create a hybrid RF-FSO system and reduce the system outage probability. The results show that joint implementation of the RF and FSO links leads to considerable performance improvement, compared to the cases with only FSO-based communication.

  16. Optimisation of the link volume for weakest link failure prediction in NBG-18 nuclear graphite

    International Nuclear Information System (INIS)

    Hindley, Michael P.; Groenwold, Albert A.; Blaine, Deborah C.; Becker, Thorsten H.

    2014-01-01

    This paper describes the process for approximating the optimal size of a link volume required for weakest link failure calculation in nuclear graphite, with NBG-18 used as an example. As part of the failure methodology, the link volume is defined in terms of two grouping criteria. The first criterion is a factor of the maximum grain size and the second criterion is a function of an equivalent stress limit. A methodology for approximating these grouping criteria is presented. The failure methodology employs finite element analysis (FEA) in order to predict the failure load, at 50% probability of failure. The average experimental failure load, as determined for 26 test geometries, is used to evaluate the accuracy of the weakest link failure calculations. The influence of the two grouping criteria on the failure load prediction is evaluated by defining an error in prediction across all test cases. Mathematical optimisation is used to find the minimum error across a range of test case failure predictions. This minimum error is shown to deliver the most accurate failure prediction across a whole range of components, although some test cases in the range predict conservative failure load. The mathematical optimisation objective function is penalised to account for non-conservative prediction of the failure load for any test case. The optimisation is repeated and a link volume found for conservative failure prediction. The failure prediction for each test case is evaluated, in detail, for the proposed link volumes. Based on the analysis, link design volumes for NBG-18 are recommended for either accurate or conservative failure prediction

  17. Simulation of Controller Pilot Data Link Communications over VHF Digital Link Mode 3

    Science.gov (United States)

    Bretmersky, Steven C.; Murawski, Robert; Nguyen, Thanh C.; Raghavan, Rajesh S.

    2004-01-01

    The Federal Aviation Administration (FAA) has established an operational plan for the future Air Traffic Management (ATM) system, in which the Controller Pilot Data Link Communications (CPDLC) is envisioned to evolve into digital messaging that will take on an ever increasing role in controller to pilot communications, significantly changing the way the National Airspace System (NAS) is operating. According to FAA, CPDLC represents the first phase of the transition from the current analog voice system to an International Civil Aviation Organization (ICAO) compliant system in which digital communication becomes the alternate and perhaps primary method of routine communication. The CPDLC application is an Air Traffic Service (ATS) application in which pilots and controllers exchange messages via an addressed data link. CPDLC includes a set of clearance, information, and request message elements that correspond to existing phraseology employed by current Air Traffic Control (ATC) procedures. These message elements encompass altitude assignments, crossing constraints, lateral deviations, route changes and clearances, speed assignments, radio frequency assignments, and various requests for information. The pilot is provided with the capability to respond to messages, to request clearances and information, to report information, and to declare/rescind an emergency. A 'free text' capability is also provided to exchange information not conforming to defined formats. This paper presents simulated results of the aeronautical telecommunication application Controller Pilot Data Link Communications over VHF Digital Link Mode 3 (VDL Mode 3). The objective of this simulation study was to determine the impact of CPDLC traffic loads, in terms of timely message delivery and capacity of the VDL Mode 3 subnetwork. The traffic model is based on and is used for generating air/ground messages with different priorities. Communication is modeled for the en route domain of the Cleveland

  18. A prototype TV-link for authentication of video information

    International Nuclear Information System (INIS)

    Richter, B.; Stein, G.; Neumann, G.; Gartner, K.J.

    1987-01-01

    In the frame of the Programme of the Federal Republic of Germany in Support of the International Atomic Energy Agency a prototype TV-link with high tamper resistance has been developed. The paper describes the technical realization of the authentication method for the transmission of video information

  19. A linked GeoData map for enabling information access

    Science.gov (United States)

    Powell, Logan J.; Varanka, Dalia E.

    2018-01-10

    OverviewThe Geospatial Semantic Web (GSW) is an emerging technology that uses the Internet for more effective knowledge engineering and information extraction. Among the aims of the GSW are to structure the semantic specifications of data to reduce ambiguity and to link those data more efficiently. The data are stored as triples, the basic data unit in graph databases, which are similar to the vector data model of geographic information systems (GIS); that is, a node-edge-node model that forms a graph of semantically related information. The GSW is supported by emerging technologies such as linked geospatial data, described below, that enable it to store and manage geographical data that require new cartographic methods for visualization. This report describes a map that can interact with linked geospatial data using a simulation of a data query approach called the browsable graph to find information that is semantically related to a subject of interest, visualized using the Data Driven Documents (D3) library. Such a semantically enabled map functions as a map knowledge base (MKB) (Varanka and Usery, 2017).A MKB differs from a database in an important way. The central element of a triple, alternatively called the edge or property, is composed of a logic formalization that structures the relation between the first and third parts, the nodes or objects. Node-edge-node represents the graphic form of the triple, and the subject-property-object terms represent the data structure. Object classes connect to build a federated graph, similar to a network in visual form. Because the triple property is a logical statement (a predicate), the data graph represents logical propositions or assertions accepted to be true about the subject matter. These logical formalizations can be manipulated to calculate new triples, representing inferred logical assertions, from the existing data.To demonstrate a MKB system, a technical proof-of-concept is developed that uses geographically

  20. Mutual Information-Based Inputs Selection for Electric Load Time Series Forecasting

    Directory of Open Access Journals (Sweden)

    Nenad Floranović

    2013-02-01

    Full Text Available Providing accurate load forecast to electric utility corporations is essential in order to reduce their operational costs and increase profits. Hence, training set selection is an important preprocessing step which has to be considered in practice in order to increase the accuracy of load forecasts. The usage of mutual information (MI has been recently proposed in regression tasks, mostly for feature selection and for identifying the real instances from training sets that contains noise and outliers. This paper proposes a methodology for the training set selection in a least squares support vector machines (LS-SVMs load forecasting model. A new application of the concept of MI is presented for the selection of a training set based on MI computation between initial training set instances and testing set instances. Accordingly, several LS-SVMs models have been trained, based on the proposed methodology, for hourly prediction of electric load for one day ahead. The results obtained from a real-world data set indicate that the proposed method increases the accuracy of load forecasting as well as reduces the size of the initial training set needed for model training.

  1. INFORMATION TECHNOLOGY AND ROMANIAN HIGHER EDUCATION - EVIDENCE ON LINKED DYNAMIC

    Directory of Open Access Journals (Sweden)

    Bogdan Nichifor

    2014-07-01

    Full Text Available The link between education, in general, and information technologies is one that does not necessarily have to be demonstrated. But it is interesting to see the specific link that is established between these two components of modern society. In recent years, part-time education forms tend to occupy an increasingly important position in the Romanian higher education from the perspective of the total number of students opting for distance learning or traditional part-time learning. This development occurred amid expansion of information technology - more and more households have Internet access and frequency of its use is increasing from year to year – in the context in which forms of part – time learning require the use of this means of information and communication. On this background more and more people over 25 years become interested in further developing their studies, including employed persons opting for further studies, increasing the share of students over 25 years in total students and the share of employed population over 25 years with higher education in total in respective age group.

  2. A Review Paper On Exploring Text Link And Spacial-Temporal Information In Social Media Networks

    Directory of Open Access Journals (Sweden)

    Dr. Mamta Madan

    2015-03-01

    Full Text Available ABSTRACT The objective of this paper is to have a literature review on the various methods to mine the knowledge from the social media by taking advantage of embedded heterogeneous information. Specifically we are trying to review different types of mining framework which provides us useful information from these networks that have heterogeneous data types including text spacial-temporal and data association LINK information. Firstly we will discuss the link mining to study the link structure with respect to Social Media SM. Secondly we summarize the various text mining models thirdly we shall review spacial as well the temporal models to extract or detect the frequent related topics from SM. Fourthly we will try to figure out few improvised models that take advantage of the link textual temporal and spacial information which motivates to discover progressive principles and fresh methodologies for DM Data Mining in social media networks SMNs.

  3. Discussion of a method for providing general risk information by linking with the nuclear information

    International Nuclear Information System (INIS)

    Shobu, Nobuhiro; Yokomizo, Shirou; Umezawa, Sayaka

    2004-06-01

    'Risk information navigator (http://www.ricotti.jp/risknavi/)', an internet tool for arousing public interest and fostering people's risk literacy, has been developed as the contents for the official website of Techno Community Square 'RICOTTI' (http://www.ricotti.jp) at TOKAI village. In this report we classified the risk information into the fields, Health/Daily Life', 'Society/Crime/Disaster' and Technology/Environment/Energy', for the internet tool contents. According to these categories we discussed a method for providing various risk information on general fields by linking with the information on nuclear field. The web contents are attached to this report with the CD-R media. (author)

  4. Cognitive Load Theory and the Effects of Transient Information on the Modality Effect

    Science.gov (United States)

    Leahy, Wayne; Sweller, John

    2016-01-01

    Based on cognitive load theory and the "transient information effect," this paper investigated the "modality effect" while interpreting a contour map. The length and complexity of auditory and visual text instructions were manipulated. Experiment 1 indicated that longer audio text information within a presentation was inferior…

  5. Improving Information on Maternal Medication Use by Linking Prescription Data to Congenital Anomaly Registers

    DEFF Research Database (Denmark)

    de Jonge, Linda; Garne, Ester; Gini, Rosa

    2015-01-01

    INTRODUCTION: Research on associations between medication use during pregnancy and congenital anomalies is significative for assessing the safe use of a medicine in pregnancy. Congenital anomaly (CA) registries do not have optimal information on medicine exposure, in contrast to prescription...... databases. Linkage of prescription databases to the CA registries is a potentially effective method of obtaining accurate information on medicine use in pregnancies and the risk of congenital anomalies. METHODS: We linked data from primary care and prescription databases to five European Surveillance...... of Congenital Anomalies (EUROCAT) CA registries. The linkage was evaluated by looking at linkage rate, characteristics of linked and non-linked cases, first trimester exposure rates for six groups of medicines according to the prescription data and information on medication use registered in the CA databases...

  6. Performance of local information-based link prediction: a sampling perspective

    Science.gov (United States)

    Zhao, Jichang; Feng, Xu; Dong, Li; Liang, Xiao; Xu, Ke

    2012-08-01

    Link prediction is pervasively employed to uncover the missing links in the snapshots of real-world networks, which are usually obtained through different kinds of sampling methods. In the previous literature, in order to evaluate the performance of the prediction, known edges in the sampled snapshot are divided into the training set and the probe set randomly, without considering the underlying sampling approaches. However, different sampling methods might lead to different missing links, especially for the biased ways. For this reason, random partition-based evaluation of performance is no longer convincing if we take the sampling method into account. In this paper, we try to re-evaluate the performance of local information-based link predictions through sampling method governed division of the training set and the probe set. It is interesting that we find that for different sampling methods, each prediction approach performs unevenly. Moreover, most of these predictions perform weakly when the sampling method is biased, which indicates that the performance of these methods might have been overestimated in the prior works.

  7. Pupil Dilation and EEG Alpha Frequency Band Power Reveal Load on Executive Functions for Link-Selection Processes during Text Reading.

    Directory of Open Access Journals (Sweden)

    Christian Scharinger

    Full Text Available Executive working memory functions play a central role in reading comprehension. In the present research we were interested in additional load imposed on executive functions by link-selection processes during computer-based reading. For obtaining process measures, we used a methodology of concurrent electroencephalographic (EEG and eye-tracking data recording that allowed us to compare epochs of pure text reading with epochs of hyperlink-like selection processes in an online reading situation. Furthermore, this methodology allowed us to directly compare the two physiological load-measures EEG alpha frequency band power and pupil dilation. We observed increased load on executive functions during hyperlink-like selection processes on both measures in terms of decreased alpha frequency band power and increased pupil dilation. Surprisingly however, the two measures did not correlate. Two additional experiments were conducted that excluded potential perceptual, motor, or structural confounds. In sum, EEG alpha frequency band power and pupil dilation both turned out to be sensitive measures for increased load during hyperlink-like selection processes in online text reading.

  8. Linking the environmental loads to the fate of PPCPs in Beijing: Considering both the treated and untreated wastewater sources

    International Nuclear Information System (INIS)

    Wang, Bin; Dai, Guohua; Deng, Shubo; Huang, Jun; Wang, Yujue; Yu, Gang

    2015-01-01

    The environmental loads of pharmaceutical and personal care products (PPCPs) in Beijing were estimated from direct discharge of untreated wastewater and WWTP treated effluent. The annual environmental loads of 15 PPCP components ranged from 16.3 kg (propranolol) to 9.85 tons (caffeine). A fugacity model was developed to successfully estimate the PPCP pollution based on the estimated environmental load. The modeled results approximated the observed PPCP concentrations in Beijing. The untreated wastewater contributed significantly to PPCP pollution in Beijing, ranging from 46% (propranolol) to 99% (caffeine). The total environmental burden of target PPCPs ranged from 0.90 kg (propranolol) to 536 kg (caffeine). Water is the most important media for the fate of PPCPs. Monte Carlo-based concentration distributions of PPCPs are consistent with the observed results. The most important way to reduce the PPCP pollution is to both improve wastewater collection rate and adopt deep treatment technologies. - Highlights: • Annual environmental loads of PPCPs ranged from 16.3 kg to 9.85 tons in Beijing. • The environmental loads can be linked to PPCP pollution by fugacity model. • Untreated wastewater significantly contributed to PPCP pollution in Beijing. • The environmental burden of 15 PPCPs in Beijing ranged from 0.90 kg to 536 kg. • Uncertainty simulation successfully generated PPCP concentration distribution. - The environmental loads from both the treated and untreated wastewater sources contribute to PPCPs pollution in the surface water in Beijing, China

  9. Linking CDOM spectral absorption to dissolved organic carbon concentrations and loadings in boreal estuaries

    Science.gov (United States)

    Asmala, Eero; Stedmon, Colin A.; Thomas, David N.

    2012-10-01

    The quantity of chromophoric dissolved organic matter (CDOM) and dissolved organic carbon (DOC) in three Finnish estuaries (Karjaanjoki, Kyrönjoki and Kiiminkijoki) was investigated, with respect to predicting DOC concentrations and loadings from spectral CDOM absorption measurements. Altogether 87 samples were collected from three estuarine transects which were studied in three seasons, covering a salinity range between 0 and 6.8, and DOC concentrations from 1572 μmol l-1 in freshwater to 222 μmol l-1 in coastal waters. CDOM absorption coefficient, aCDOM(375) values followed the trend in DOC concentrations across the salinity gradient and ranged from 1.67 to 33.4 m-1. The link between DOC and CDOM was studied using a range of wavelengths and algorithms. Wavelengths between 250 and 270 nm gave the best predictions with single linear regression. Total dissolved iron was found to influence the prediction in wavelengths above 520 nm. Despite significant seasonal and spatial differences in DOC-CDOM models, a universal relationship was tested with an independent data set and found to be robust. DOC and CDOM yields (loading/catchment area) from the catchments ranged from 1.98 to 5.44 g C m-2 yr-1, and 1.67 to 11.5 aCDOM(375) yr-1, respectively.

  10. Computer-aided load monitoring system for nuclear power plant steel framing structures

    International Nuclear Information System (INIS)

    Skaczylo, A.T.; Fung, S-J; Hooks, R.W.

    1984-01-01

    The design of nuclear power plant steel framing structures is a long and involved process. It is often complicated by numerous changes in design loads as a result of additions, deletions and modifications of HVAC hangers, cable tray hangers, electric conduit hangers, and small bore and large bore mechanical component supports. Manual tracking of load changes of thousands of supports and their impact to the structural steel design adequacy is very time-consuming and is susceptible to errors. This paper presents a computer-aided load monitoring system using the latest technology of data base management and interactive computer software. By linking the data base to analysis and investigation computer programs, the engineer has a very powerful tool to monitor not only the load revisions but also their impact on the steel structural floor framing members and connections. Links to reporting programs allow quick information retrieval in the form of comprehensive reports. Drawing programs extract data from the data base to draw hanger load system drawings on a computer-aided drafting system. These capabilities allow engineers to minimize modifications by strategically locating new hangers or rearranging auxiliary steel configuration

  11. Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms.

    Directory of Open Access Journals (Sweden)

    2005-09-01

    Full Text Available A new memory is initially labile and becomes stabilized through a process of consolidation, which depends on gene expression. Stable memories, however, can again become labile if reactivated by recall and require another phase of protein synthesis in order to be maintained. This process is known as reconsolidation. The functional significance of the labile phase of reconsolidation is unknown; one hypothesis proposes that it is required to link new information with reactivated memories. Reconsolidation is distinct from the initial consolidation, and one distinction is that the requirement for specific proteins or general protein synthesis during the two processes occurs in different brain areas. Here, we identified an anatomically distinctive molecular requirement that doubly dissociates consolidation from reconsolidation of an inhibitory avoidance memory. We then used this requirement to investigate whether reconsolidation and consolidation are involved in linking new information with reactivated memories. In contrast to what the hypothesis predicted, we found that reconsolidation does not contribute to the formation of an association between new and reactivated information. Instead, it recruits mechanisms similar to those underlying consolidation of a new memory. Thus, linking new information to a reactivated memory is mediated by consolidation and not reconsolidation mechanisms.

  12. Wireless Energy and Information Transmission in FSO and RF-FSO Links

    KAUST Repository

    Makki, Behrooz; Svensson, Tommy; Buisman, Koen; Perez, Joaquin; Alouini, Mohamed-Slim

    2017-01-01

    We propose and analyze a wireless energy and information transmission scheme in free-space optical (FSO) links. The results are presented for both quasi-static and fast-fading conditions. We derive closed-form expressions for throughput, outage

  13. Securing the communication of medical information using local biometric authentication and commercial wireless links.

    Science.gov (United States)

    Ivanov, Vladimir I; Yu, Paul L; Baras, John S

    2010-09-01

    Medical information is extremely sensitive in nature - a compromise, such as eavesdropping or tampering by a malicious third party, may result in identity theft, incorrect diagnosis and treatment, and even death. Therefore, it is important to secure the transfer of medical information from the patient to the recording system. We consider a portable, wireless device transferring medical information to a remote server. We decompose this problem into two sub-problems and propose security solutions to each of them: (1) to secure the link between the patient and the portable device, and (2) to secure the link between the portable device and the network. Thus we push the limits of the network security to the edge by authenticating the user using their biometric information; authenticating the device to the network at the physical layer; and strengthening the security of the wireless link with a key exchange mechanism. The proposed authentication methods can be used for recording the readings of medical data in a central database and for accessing medical records in various settings.

  14. Cognitive Load and Cooperation

    DEFF Research Database (Denmark)

    Døssing, Felix Sebastian; Piovesan, Marco; Wengström, Erik Roland

    2017-01-01

    We study the effect of intuitive and reflective processes on cooperation using cognitive load. Compared with time constraint, which has been used in the previous literature, cognitive load is a more direct way to block reflective processes, and thus a more suitable way to study the link between...... intuition and cooperation. Using a repeated public goods game, we study the effect of different levels of cognitive load on contributions. We show that a higher cognitive load increases the initial level of cooperation. In particular, subjects are significantly less likely to fully free ride under high...... cognitive load....

  15. Bit Loading Algorithms for Cooperative OFDM Systems

    Directory of Open Access Journals (Sweden)

    Gui Bo

    2008-01-01

    Full Text Available Abstract We investigate the resource allocation problem for an OFDM cooperative network with a single source-destination pair and multiple relays. Assuming knowledge of the instantaneous channel gains for all links in the entire network, we propose several bit and power allocation schemes aiming at minimizing the total transmission power under a target rate constraint. First, an optimal and efficient bit loading algorithm is proposed when the relay node uses the same subchannel to relay the information transmitted by the source node. To further improve the performance gain, subchannel permutation, in which the subchannels are reallocated at relay nodes, is considered. An optimal subchannel permutation algorithm is first proposed and then an efficient suboptimal algorithm is considered to achieve a better complexity-performance tradeoff. A distributed bit loading algorithm is also proposed for ad hoc networks. Simulation results show that significant performance gains can be achieved by the proposed bit loading algorithms, especially when subchannel permutation is employed.

  16. Bit Loading Algorithms for Cooperative OFDM Systems

    Directory of Open Access Journals (Sweden)

    Bo Gui

    2007-12-01

    Full Text Available We investigate the resource allocation problem for an OFDM cooperative network with a single source-destination pair and multiple relays. Assuming knowledge of the instantaneous channel gains for all links in the entire network, we propose several bit and power allocation schemes aiming at minimizing the total transmission power under a target rate constraint. First, an optimal and efficient bit loading algorithm is proposed when the relay node uses the same subchannel to relay the information transmitted by the source node. To further improve the performance gain, subchannel permutation, in which the subchannels are reallocated at relay nodes, is considered. An optimal subchannel permutation algorithm is first proposed and then an efficient suboptimal algorithm is considered to achieve a better complexity-performance tradeoff. A distributed bit loading algorithm is also proposed for ad hoc networks. Simulation results show that significant performance gains can be achieved by the proposed bit loading algorithms, especially when subchannel permutation is employed.

  17. The Effects of Presentation Method and Information Density on Visual Search Ability and Working Memory Load

    Science.gov (United States)

    Chang, Ting-Wen; Kinshuk; Chen, Nian-Shing; Yu, Pao-Ta

    2012-01-01

    This study investigates the effects of successive and simultaneous information presentation methods on learner's visual search ability and working memory load for different information densities. Since the processing of information in the brain depends on the capacity of visual short-term memory (VSTM), the limited information processing capacity…

  18. HIV Viral Load: MedlinePlus Lab Test Information

    Science.gov (United States)

    ... this page: https://medlineplus.gov/labtests/hivviralload.html HIV Viral Load To use the sharing features on this page, please enable JavaScript. What is an HIV Viral Load? An HIV viral load is a ...

  19. Scratch that itch: revisiting links between self-directed behaviour and parasitological, social and environmental factors in a free-ranging primate.

    Science.gov (United States)

    Duboscq, Julie; Romano, Valéria; Sueur, Cédric; MacIntosh, Andrew J J

    2016-11-01

    Different hypotheses explain variation in the occurrence of self-directed behaviour such as scratching and self-grooming: a parasite hypothesis linked with ectoparasite load, an environmental hypothesis linked with seasonal conditions and a social hypothesis linked with social factors. These hypotheses are not mutually exclusive but are often considered separately. Here, we revisited these hypotheses together in female Japanese macaques ( Macaca fuscata fuscata ) of Kōjima islet, Japan. We input occurrences of scratching and self-grooming during focal observations in models combining parasitological (lice load), social (dominance rank, social grooming, aggression received and proximity), and environmental (rainfall, temperature and season) variables. Using an information-theory approach, we simultaneously compared the explanatory value of models against each other using variation in Akaike's information criterion and Akaike's weights. We found that evidence for models with lice load, with or without environmental-social parameters, was stronger than that for other models. In these models, scratching was positively associated with lice load and social grooming whereas self-grooming was negatively associated with lice load and positively associated with social grooming, dominance rank and number of female neighbours. This study indicates that the study animals scratch primarily because of an immune/stimulus itch, possibly triggered by ectoparasite bites/movements. It also confirms that self-grooming could act as a displacement activity in the case of social uncertainty. We advocate that biological hypotheses be more broadly considered even when investigating social processes, as one does not exclude the other.

  20. Self-Instructional Module Based on Cognitive Load Theory: A Study on Information Retention among Trainee Teachers

    Science.gov (United States)

    Ong, Chiek Pin; Tasir, Zaidatun

    2015-01-01

    The aim of the research is to study the information retention among trainee teachers using a self-instructional printed module based on Cognitive Load Theory for learning spreadsheet software. Effective pedagogical considerations integrating the theoretical concepts related to cognitive load are reflected in the design and development of the…

  1. Linked Open Data in the Global Change Information System (GCIS)

    Science.gov (United States)

    Tilmes, Curt A.

    2012-01-01

    The U.S. Global Change Research Program (http://globalchange.gov) coordinates and integrates federal research on changes in the global environment and their implications for society. The USGCRP is developing a Global Change Information System (GCIS) that will centralize access to data and information related to global change across the U.S. federal government. The first implementation will focus on the 2013 National Climate Assessment (NCA) . (http://assessment.globalchange.gov) The NCA integrates, evaluates, and interprets the findings of the USGCRP; analyzes the effects of global change on the natural environment, agriculture, energy production and use, land and water resources, transportation, human health and welfare, human social systems, and biological diversity; and analyzes current trends in global change, both human-induced and natural, and projects major trends for the subsequent 25 to 100 years. The NCA has received over 500 distinct technical inputs to the process, many of which are reports distilling and synthesizing even more information, coming from thousands of individuals around the federal, state and local governments, academic institutions and non-governmental organizations. The GCIS will present a web-based version of the NCA including annotations linking the findings and content of the NCA with the scientific research, datasets, models, observations, etc. that led to its conclusions. It will use semantic tagging and a linked data approach, assigning globally unique, persistent, resolvable identifiers to all of the related entities and capturing and presenting the relationships between them, both internally and referencing out to other linked data sources and back to agency data centers. The developing W3C PROV Data Model and ontology will be used to capture the provenance trail and present it in both human readable web pages and machine readable formats such as RDF and SPARQL. This will improve visibility into the assessment process, increase

  2. Lewis Information Network (LINK): Background and overview

    Science.gov (United States)

    Schulte, Roger R.

    1987-01-01

    The NASA Lewis Research Center supports many research facilities with many isolated buildings, including wind tunnels, test cells, and research laboratories. These facilities are all located on a 350 acre campus adjacent to the Cleveland Hopkins Airport. The function of NASA-Lewis is to do basic and applied research in all areas of aeronautics, fluid mechanics, materials and structures, space propulsion, and energy systems. These functions require a great variety of remote high speed, high volume data communications for computing and interactive graphic capabilities. In addition, new requirements for local distribution of intercenter video teleconferencing and data communications via satellite have developed. To address these and future communications requirements for the next 15 yrs, a project team was organized to design and implement a new high speed communication system that would handle both data and video information in a common lab-wide Local Area Network. The project team selected cable television broadband coaxial cable technology as the communications medium and first installation of in-ground cable began in the summer of 1980. The Lewis Information Network (LINK) became operational in August 1982 and has become the backbone of all data communications and video.

  3. Links between fluid mechanics and quantum mechanics: a model for information in economics?

    Science.gov (United States)

    Haven, Emmanuel

    2016-05-28

    This paper tallies the links between fluid mechanics and quantum mechanics, and attempts to show whether those links can aid in beginning to build a formal template which is usable in economics models where time is (a)symmetric and memory is absent or present. An objective of this paper is to contemplate whether those formalisms can allow us to model information in economics in a novel way. © 2016 The Author(s).

  4. Distribution load estimation - DLE

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A. [VTT Energy, Espoo (Finland)

    1996-12-31

    The load research project has produced statistical information in the form of load models to convert the figures of annual energy consumption to hourly load values. The reliability of load models is limited to a certain network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to make improvements in the load models. Distribution load estimation (DLE) is the method developed here to improve load estimates from the load models. The method is also quite cheap to apply as it utilises information that is already available in SCADA systems

  5. Distribution load estimation - DLE

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A [VTT Energy, Espoo (Finland)

    1997-12-31

    The load research project has produced statistical information in the form of load models to convert the figures of annual energy consumption to hourly load values. The reliability of load models is limited to a certain network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to make improvements in the load models. Distribution load estimation (DLE) is the method developed here to improve load estimates from the load models. The method is also quite cheap to apply as it utilises information that is already available in SCADA systems

  6. Capacity of cognitive radio under imperfect secondary and cross link channel state information

    KAUST Repository

    Sboui, Lokman

    2011-09-01

    In this paper, we study the ergodic capacity of secondary user channel in a spectrum sharing scenario in which the secondary transmitter is instantaneously aware of estimated versions of the cross link (between the secondary transmitter and the primary receiver) and the secondary link Channel State Information (CSI). The secondary link optimal power profile along with the ergodic capacity are derived for a class of fading channels, under an average power constraint and an instantaneous interference outage constraint. We also show that our framework is rather general as it encompasses several previously studied spectrum sharing settings as special cases. In order to gain some insights on the capacity behavior, numerical results are shown for independent Rayleigh fading channels where it is found for instance, that at low SNR regime, only the secondary channel estimation matters and that the cross link CSI has no effect on the ergodic capacity; whereas at high SNR regime, the capacity is rather driven by the cross link CSI. © 2011 IEEE.

  7. User Information Needs for Environmental Opinion-forming and Decision-making in Link-enriched Video

    NARCIS (Netherlands)

    A.C. Palumbo; L. Hardman (Lynda)

    2013-01-01

    htmlabstractLink-enriched video can support users in informative processes of environmental opinion-forming and decision-making. To enable this, we need to specify the information that should be captured in an annotation schema for describing the video. We conducted expert interviews to elicit

  8. Comparing Multi-Informant Assessment Measures of Parental Monitoring and Their Links with Adolescent Delinquent Behavior

    Science.gov (United States)

    Augenstein, Tara M.; Thomas, Sarah A.; Ehrlich, Katherine B.; Daruwala, Samantha; Reyes, Shelby M.; Chrabaszcz, Jeffrey S.; De Los Reyes, Andres

    2016-01-01

    SYNOPSIS Objective Parents’ poor monitoring of adolescents’ whereabouts and activities is commonly linked to adolescents’ increased engagement in delinquent behaviors. Yet, different domains of parental monitoring (parental monitoring behaviors vs. parental knowledge) and reports from multiple informants (parent vs. adolescent) may vary in their links to delinquent behavior. Design Seventy-four parental caregivers and 74 adolescents completed survey measures of parental monitoring and knowledge, and adolescents completed self-report surveys of delinquent behavior. Results We observed low-to-moderate magnitudes of correspondence between parent- and adolescent-reports of parental monitoring behaviors and parental knowledge. Adolescent self-reported delinquent behavior related to parent and adolescent reports of parental monitoring behaviors and parental knowledge, with adolescents who self-reported engagement in delinquent behaviors evidencing lower levels of parental knowledge and higher levels of poor monitoring compared to adolescents who did not self-report engagement in delinquent behaviors. Adolescent self-reported engagement in delinquent behaviors evidenced stronger links to parental monitoring when based on adolescent reports of monitoring (relative to parent reports), whereas stronger links held between adolescent self-reported delinquent behavior and parental knowledge when based on parent reports of knowledge (relative to adolescent reports). Conclusions Links between monitoring and adolescents’ delinquent behavior vary by the kind of monitoring measure completed as well as the informant completing the measure. These findings inform measurement selection in research and clinical assessments of parental monitoring and adolescent delinquent behavior. PMID:27482171

  9. Vision-based stress estimation model for steel frame structures with rigid links

    Science.gov (United States)

    Park, Hyo Seon; Park, Jun Su; Oh, Byung Kwan

    2017-07-01

    This paper presents a stress estimation model for the safety evaluation of steel frame structures with rigid links using a vision-based monitoring system. In this model, the deformed shape of a structure under external loads is estimated via displacements measured by a motion capture system (MCS), which is a non-contact displacement measurement device. During the estimation of the deformed shape, the effective lengths of the rigid link ranges in the frame structure are identified. The radius of the curvature of the structural member to be monitored is calculated using the estimated deformed shape and is employed to estimate stress. Using MCS in the presented model, the safety of a structure can be assessed gauge-freely. In addition, because the stress is directly extracted from the radius of the curvature obtained from the measured deformed shape, information on the loadings and boundary conditions of the structure are not required. Furthermore, the model, which includes the identification of the effective lengths of the rigid links, can consider the influences of the stiffness of the connection and support on the deformation in the stress estimation. To verify the applicability of the presented model, static loading tests for a steel frame specimen were conducted. By comparing the stress estimated by the model with the measured stress, the validity of the model was confirmed.

  10. Spreading the load: mobile information and communications technologies and their effect on information overload

    Directory of Open Access Journals (Sweden)

    D.K. Allan

    2005-01-01

    Full Text Available Introduction. We report on a small-scale research project which examined the impact of mobile technologies on the users' experience of information overload. The project focused on a group of worker who have had relatively little attention in both the mobile technology and information overload literatures: senior managers. Method. The case study approach was adopted, as complementary to an incremental approach to theory building. An inductive approach is adopted, in which data are collected and the findings are interpreted in the light of previous work. The case site was West Yorkshire Police Force in the UK where BlackBerry handhelds were being used by senior officers. Analysis. A semi-structured interview schedule was developed and applied in face-to-face interviews with the Senior Management Team and their secretaries. All interviews were recorded and the transcripts of the interviews analysed, using qualitative coding. Results. A conceptual model of the interactions and relationships among the key elements that drive and mediate the information flows and information behaviour within a complex organizational environment was developed. Managers' information behaviour and coping strategies were found to have changed since the introduction of mobile devices. Officers are more likely to deal with information received sooner, thereby resulting in less queuing of messages (although filtering strategies still prevail. Approximation (responding in a non-precise way was also found to have increased. In this particular implementation, the mobile technology has not altered the information-pull behaviour of managers. Conclusion. The main finding is that personal information management is now distributed more evenly throughout the day. Thus, the technology has enabled officers to 'spread the load' and, in doing so, has helped to ease some of the pressures created by information overload.

  11. Linking Earth Observations and Models to Societal Information Needs: The Case of Coastal Flooding

    Science.gov (United States)

    Buzzanga, B. A.; Plag, H. P.

    2016-12-01

    Coastal flooding is expected to increase in many areas due to sea level rise (SLR). Many societal applications such as emergency planning and designing public services depend on information on how the flooding spectrum may change as a result of SLR. To identify the societal information needs a conceptual model is needed that identifies the key stakeholders, applications, and information and observation needs. In the context of the development of the Global Earth Observation System of Systems (GEOSS), which is implemented by the Group on Earth Observations (GEO), the Socio-Economic and Environmental Information Needs Knowledge Base (SEE-IN KB) is developed as part of the GEOSS Knowledge Base. A core function of the SEE-IN KB is to facilitate the linkage of societal information needs to observations, models, information and knowledge. To achieve this, the SEE-IN KB collects information on objects such as user types, observational requirements, societal goals, models, and datasets. Comprehensive information concerning the interconnections between instances of these objects is used to capture the connectivity and to establish a conceptual model as a network of networks. The captured connectivity can be used in searches to allow users to discover products and services for their information needs, and providers to search for users and applications benefiting from their products. It also allows to answer "What if?" questions and supports knowledge creation. We have used the SEE-IN KB to develop a conceptual model capturing the stakeholders in coastal flooding and their information needs, and to link these elements to objects. We show how the knowledge base enables the transition of scientific data to useable information by connecting individuals such as city managers to flood maps. Within the knowledge base, these same users can request information that improves their ability to make specific planning decisions. These needs are linked to entities within research

  12. Simultaneous Wireless Power Transfer and Data Communication Using Synchronous Pulse-Controlled Load Modulation.

    Science.gov (United States)

    Mao, Shitong; Wang, Hao; Zhu, Chunbo; Mao, Zhi-Hong; Sun, Mingui

    2017-10-01

    Wireless Power Transfer (WPT) and wireless data communication are both important problems of research with various applications, especially in medicine. However, these two problems are usually studied separately. In this work, we present a joint study of both problems. Most medical electronic devices, such as smart implants, must have both a power supply to allow continuous operation and a communication link to pass information. Traditionally, separate wireless channels for power transfer and communication are utilized, which complicate the system structure, increase power consumption and make device miniaturization difficult. A more effective approach is to use a single wireless link with both functions of delivering power and passing information. We present a design of such a wireless link in which power and data travel in opposite directions. In order to aggressively miniaturize the implant and reduce power consumption, we eliminate the traditional multi-bit Analog-to-Digital Converter (ADC), digital memory and data transmission circuits all together. Instead, we use a pulse stream, which is obtained from the original biological signal, by a sigma-delta converter and an edge detector, to alter the load properties of the WPT channel. The resulting WPT signal is synchronized with the load changes therefore requiring no memory elements to record inter-pulse intervals. We take advantage of the high sensitivity of the resonant WPT to the load change, and the system dynamic response is used to transfer each pulse. The transient time of the WPT system is analyzed using the coupling mode theory (CMT). Our experimental results show that the memoryless approach works well for both power delivery and data transmission, providing a new wireless platform for the design of future miniaturized medical implants.

  13. Load-redistribution strategy based on time-varying load against cascading failure of complex network

    International Nuclear Information System (INIS)

    Liu Jun; Shi Xin; Wang Kai; Shi Wei-Ren; Xiong Qing-Yu

    2015-01-01

    Cascading failure can cause great damage to complex networks, so it is of great significance to improve the network robustness against cascading failure. Many previous existing works on load-redistribution strategies require global information, which is not suitable for large scale networks, and some strategies based on local information assume that the load of a node is always its initial load before the network is attacked, and the load of the failure node is redistributed to its neighbors according to their initial load or initial residual capacity. This paper proposes a new load-redistribution strategy based on local information considering an ever-changing load. It redistributes the loads of the failure node to its nearest neighbors according to their current residual capacity, which makes full use of the residual capacity of the network. Experiments are conducted on two typical networks and two real networks, and the experimental results show that the new load-redistribution strategy can reduce the size of cascading failure efficiently. (paper)

  14. Does high memory load kick task-irrelevant information out of visual working memory?

    Science.gov (United States)

    Yin, Jun; Zhou, Jifan; Xu, Haokui; Liang, Junying; Gao, Zaifeng; Shen, Mowei

    2012-04-01

    The limited capacity of visual working memory (VWM) requires the existence of an efficient information selection mechanism. While it has been shown that under low VWM load, an irrelevant simple feature can be processed, its fate under high load (e.g., six objects) remains unclear. We explored this issue by probing the "irrelevant-change distracting effect," in which the change of a stored irrelevant feature affects performance. Simple colored shapes were used as stimuli, with color as the target. Using a whole-probe method (presenting six objects in both the memory and test arrays), in Experiment 1 we found that a change to one of the six shapes led to a significant distracting effect. Using a partial-probe method (presenting the probe either at the screen center or at a location selected from the memory array), in Experiment 2 we showed the distracting effect again. These results suggest that irrelevant simple features can be stored into VWM, regardless of memory load.

  15. Towards linked open gene mutations data

    Science.gov (United States)

    2012-01-01

    Background With the advent of high-throughput technologies, a great wealth of variation data is being produced. Such information may constitute the basis for correlation analyses between genotypes and phenotypes and, in the future, for personalized medicine. Several databases on gene variation exist, but this kind of information is still scarce in the Semantic Web framework. In this paper, we discuss issues related to the integration of mutation data in the Linked Open Data infrastructure, part of the Semantic Web framework. We present the development of a mapping from the IARC TP53 Mutation database to RDF and the implementation of servers publishing this data. Methods A version of the IARC TP53 Mutation database implemented in a relational database was used as first test set. Automatic mappings to RDF were first created by using D2RQ and later manually refined by introducing concepts and properties from domain vocabularies and ontologies, as well as links to Linked Open Data implementations of various systems of biomedical interest. Since D2RQ query performances are lower than those that can be achieved by using an RDF archive, generated data was also loaded into a dedicated system based on tools from the Jena software suite. Results We have implemented a D2RQ Server for TP53 mutation data, providing data on a subset of the IARC database, including gene variations, somatic mutations, and bibliographic references. The server allows to browse the RDF graph by using links both between classes and to external systems. An alternative interface offers improved performances for SPARQL queries. The resulting data can be explored by using any Semantic Web browser or application. Conclusions This has been the first case of a mutation database exposed as Linked Data. A revised version of our prototype, including further concepts and IARC TP53 Mutation database data sets, is under development. The publication of variation information as Linked Data opens new perspectives

  16. Towards linked open gene mutations data.

    Science.gov (United States)

    Zappa, Achille; Splendiani, Andrea; Romano, Paolo

    2012-03-28

    With the advent of high-throughput technologies, a great wealth of variation data is being produced. Such information may constitute the basis for correlation analyses between genotypes and phenotypes and, in the future, for personalized medicine. Several databases on gene variation exist, but this kind of information is still scarce in the Semantic Web framework. In this paper, we discuss issues related to the integration of mutation data in the Linked Open Data infrastructure, part of the Semantic Web framework. We present the development of a mapping from the IARC TP53 Mutation database to RDF and the implementation of servers publishing this data. A version of the IARC TP53 Mutation database implemented in a relational database was used as first test set. Automatic mappings to RDF were first created by using D2RQ and later manually refined by introducing concepts and properties from domain vocabularies and ontologies, as well as links to Linked Open Data implementations of various systems of biomedical interest. Since D2RQ query performances are lower than those that can be achieved by using an RDF archive, generated data was also loaded into a dedicated system based on tools from the Jena software suite. We have implemented a D2RQ Server for TP53 mutation data, providing data on a subset of the IARC database, including gene variations, somatic mutations, and bibliographic references. The server allows to browse the RDF graph by using links both between classes and to external systems. An alternative interface offers improved performances for SPARQL queries. The resulting data can be explored by using any Semantic Web browser or application. This has been the first case of a mutation database exposed as Linked Data. A revised version of our prototype, including further concepts and IARC TP53 Mutation database data sets, is under development.The publication of variation information as Linked Data opens new perspectives: the exploitation of SPARQL searches on

  17. A Novel Load Balancing Scheme for Multipath Routing Protocol in MANET

    Directory of Open Access Journals (Sweden)

    Kokilamani Mounagurusamy

    2016-09-01

    Full Text Available The recent advancements in information and communication technology create a great demand for multipath routing protocols. In MANET, nodes can be arbitrarily located and can move freely at any given time. The topology of MANET can change rapidly and unpredictably. Because wireless link capacities are usually limited, congestion is possible in MANETs. Hence, balancing the load in a MANET is important since nodes with high load will deplete their batteries quickly, thereby increasing the probability of disconnecting or partitioning the network. To overcome these, the multipath protocol should be aware of load at route discovery phase. The main objective of the proposed article is to balance the load on a node and to extend the lifetime of the node due to the congestion, energy depletion and link failures. This article describes a novel load and congestion aware scheme called Path Efficient Ad-hoc On-demand Multipath Distance Vector (PE-AOMDV protocol to increase the performance of routing process in MANET in terms of congestion, end-to-end delay and load balancing. A new threshold value and a counter variable are introduced to limit the number of communication paths passing over a node in route discovery phase. For every new request the counter variable is incremented by one and the threshold value is compared to see whether the maximum number of connections has been reached or not. The proposed method is network simulator ns-2 and it is found that there is a significant improvement in the proposed scheme. It reduces the energy consumption, average end-to-end delay and normalized routing overhead. Also the proposed scheme increases packet delivery ratio, throughput and minimizes routing overheads.

  18. Dynamics of fluidic devices with applications to rotor pitch links

    Science.gov (United States)

    Scarborough, Lloyd H., III

    Coupling a Fluidic Flexible Matrix Composite (F2MC) to an air-pressurized fluid port produces a fundamentally new class of tunable vibration isolator. This fluidlastic device provides significant vibration reduction at an isolation frequency that can be tuned over a broad frequency range. The material properties and geometry of the F2MC element, as well as the port inertance, determine the isolation frequency. A unique feature of this device is that the port inertance depends on pressure so the isolation frequency can be adjusted by changing the air pressure. For constant port inertance, the isolation frequency is largely independent of the isolated mass so the device is robust to changes in load. A nonlinear model is developed to predict isolator length and port inertance. The model is linearized and the frequency response calculated. Experiments agree with theory, demonstrating a tunable isolation range from 9 Hz to 36 Hz and transmitted force reductions of up to 60 dB at the isolation frequency. Replacing rigid pitch links on rotorcraft with coupled fluidic devices has the potential to reduce the aerodynamic blade loads transmitted through the pitch links to the swashplate. Analytical models of two fluidic devices coupled with three different fluidic circuits are derived. These passive fluidlastic systems are tuned, by varying the fluid inertances and capacitances of each fluidic circuit, to reduce the transmitted pitch-link loads. The different circuit designs result in transmitted pitch link loads reduction at up to three main rotor harmonics. The simulation results show loads reduction at the targeted out-of-phase and in-phase harmonics of up to 88% and 93%, respectively. Experimental validation of two of the fluidic circuits demonstrates loads reduction of up to 89% at the out-of-phase isolation frequencies and up to 81% at the in-phase isolation frequencies. Replacing rigid pitch links on rotorcraft with fluidic pitch links changes the blade torsional

  19. Do 'enabling technologies' affect customer performance in price-responsive load programs?

    International Nuclear Information System (INIS)

    Goldman, Charles A.; Kintner-Meyer, Michael; Heffner, Grayson

    2002-01-01

    Price-responsive load (PRL) programs vary significantly in overall design, the complexity of relationships between program administrators, load aggregators, and customers, and the availability of ''enabling technologies''. Enabling technologies include such features as web-based power system and price monitoring, control and dispatch of curtailable loads, communications and information systems links to program participants, availability of interval metering data to customers in near real time, and building/facility/end-use automation and management capabilities. Two state agencies - NYSERDA in New York and the CEC in California - have been conspicuous leaders in the demonstration of demand response (DR) programs utilizing enabling technologies. In partnership with key stakeholders in these two states (e.g., grid operator, state energy agencies, and program administrators), Lawrence Berkeley National Laboratory (LBNL) and Pacific Northwest National Laboratory (PNNL) surveyed 56 customers who worked with five contractors participating in CEC or NYSERDA-sponsored DR programs. We combined market research and actual load curtailment data when available (i.e., New York) or customer load reduction targets in order to explore the relative importance of contractor's program design features, sophistication of control strategies, and reliance on enabling technologies in predicting customer's ability to deliver load reductions in DR programs targeted to large commercial/industrial customers. We found preliminary evidence that DR enabling technology has a positive effect on load curtailment potential. Many customers indicated that web-based energy information tools were useful for facilitating demand response (e.g., assessing actual performance compared to load reduction contract commitments), that multiple notification channels facilitated timely response, and that support for and use of backup generation allowed customers to achieve significant and predictable load

  20. Linking diversity and distribution to understand biodiversity gradients and inform conservation assessments

    Directory of Open Access Journals (Sweden)

    Fabricio Villalobos

    2014-03-01

    Full Text Available Broad-scale patterns of species richness result from differential coexistence among species in distinct regions of the globe, determined by the species’ ranges and their properties such as size, shape and location. Thus, species richness and ranges are inherently linked. These two biodiversity features also yield primary information for conservation assessments. However, species richness and range size have been usually studied separately and no formal analytical link has been established. In my PhD thesis, I applied and extended a recently developed conceptual and methodological framework to study geographical association among species and similarity among sites. This range–diversity framework, along with stochastic simulation modelling, allowed me to jointly evaluate the relationship between diversity and distribution, to infer potential processes underlying composite patterns of phyllostomid bats, and to use this approach to inform conservation assessments for the Mexican avifauna. I highlight the need to explore composite patterns for understanding biodiversity patterns and show how combining diversity and distributional data can help describe complex biogeographical patterns, providing a transparent and explicit application for initial conservation assessments.

  1. Linking Informal and Formal Electronics Recycling via an Interface Organization

    Directory of Open Access Journals (Sweden)

    Yoshiaki Totoki

    2013-07-01

    Full Text Available Informal recycling of electronics in the developing world has emerged as a new global environmental concern. The primary approach to address this problem has been command-and-control policies that ban informal recycling and international trade in electronic scrap. These bans are difficult to enforce and also have negative effects by reducing reuse of electronics, and employment for people in poverty. An alternate approach is to link informal and formal sectors so as to maintain economic activity while mitigating environmental damages. This article explores the idea of an interface organization that purchases components and waste from informal dismantlers and passes them on to formal processors. Environmental, economic and social implications of interface organizations are discussed. The main environmental questions to resolve are what e-scrap components should be targeted by the interface organization, i.e., circuit boards, wires, and/or plastic parts. Economically, when formal recycling is more profitable (e.g., for circuit boards, the interface organization is revenue positive. However, price subsidies are needed for copper wires and residual waste to incentivize informal dismantlers to turn in for formal processing. Socially, the potential for corruption and gaming of the system is critical and needs to be addressed.

  2. Linking Science and Society With an Environmental Information Bridge

    Science.gov (United States)

    Welling, L.; Seielstad, G.; Jones, D.; Peterson, J.

    2001-12-01

    Building learning communities to engage the public in identifying and solving local and regional environmental problems is the vision of the newly created Northern Great Plains Center for People and the Environment at the University of North Dakota. The Center serves as an Environmental Information Bridge between science and society for citizens of the region, providing information, data, and value-added remote sensing products to precision agriculture, sustainable forestry, Native American land managers, and K-lifetime educators. Guided by the needs of end users, the new Center is a prototype for a national infrastructure that meets ESE's objective to "expand and accelerate the realization of economic and societal benefits from Earth science, information, and technology". The scientific community has been good at converting raw data into useful information. However, a serious communications gap exists between the communities of scientists and non-scientists. The new Center bridges this gap, creating a many-to-many exchange of information among those who learn first about the environment and those who will put those lessons to work for their economic welfare, the betterment of the quality of their lives, and the benefit of their descendants. A major outreach component of the Center, written and produced at UND, is Our Changing Planet, a public television series aimed at increasing viewers' awareness of environmental and climate change issues. Now carried by approximately 30 public television stations the series is distributed nationwide by the National Education Television Association. The Center has also recently established a partnership with StormCenter.com, LLC, a multimedia company and fellow partner in NASA's Federation of Earth Science Information Partners that uses leading-edge technology to deliver information about the environment to regional television stations. Service to the media provides a vital link between science and the public, as local weather

  3. Linking international trademark databases to inform IP research and policy

    Energy Technology Data Exchange (ETDEWEB)

    Petrie, P.

    2016-07-01

    Researchers and policy makers are concerned with many international issues regarding trademarks, such as trademark squatting, cluttering, and dilution. Trademark application data can provide an evidence base to inform government policy regarding these issues, and can also produce quantitative insights into economic trends and brand dynamics. Currently, national trademark databases can provide insight into economic and brand dynamics at the national level, but gaining such insight at an international level is more difficult due to a lack of internationally linked trademark data. We are in the process of building a harmonised international trademark database (the “Patstat of trademarks”), in which equivalent trademarks have been identified across national offices. We have developed a pilot database that incorporates 6.4 million U.S., 1.3 million Australian, and 0.5 million New Zealand trademark applications, spanning over 100 years. The database will be extended to incorporate trademark data from other participating intellectual property (IP) offices as they join the project. Confirmed partners include the United Kingdom, WIPO, and OHIM. We will continue to expand the scope of the project, and intend to include many more IP offices from around the world. In addition to building the pilot database, we have developed a linking algorithm that identifies equivalent trademarks (TMs) across the three jurisdictions. The algorithm can currently be applied to all applications that contain TM text; i.e. around 96% of all applications. In its current state, the algorithm successfully identifies ~ 97% of equivalent TMs that are known to be linked a priori, as they have shared international registration number through the Madrid protocol. When complete, the internationally linked trademark database will be a valuable resource for researchers and policy-makers in fields such as econometrics, intellectual property rights, and brand policy. (Author)

  4. Perceived social pressure not to experience negative emotion is linked to selective attention for negative information.

    Science.gov (United States)

    Bastian, Brock; Pe, Madeline Lee; Kuppens, Peter

    2017-02-01

    Social norms and values may be important predictors of how people engage with and regulate their negative emotional experiences. Previous research has shown that social expectancies (the perceived social pressure not to feel negative emotion (NE)) exacerbate feelings of sadness. In the current research, we examined whether social expectancies may be linked to how people process emotional information. Using a modified classical flanker task involving emotional rather than non-emotional stimuli, we found that, for those who experienced low levels of NE, social expectancies were linked to the selective avoidance of negative emotional information. Those who experienced high levels of NE did not show a selective avoidance of negative emotional information. The findings suggest that, for people who experience many NEs, social expectancies may lead to discrepancies between how they think they ought to feel and the kind of emotional information they pay attention to.

  5. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... increases brain viral load and activates natural killer cells in simian immunodeficiency ... out with friends? It’s a topic you can’t ignore. Learn the Link: http://1.usa.gov/ ...

  6. Design of an Interface for Page Rank Calculation using Web Link Attributes Information

    Directory of Open Access Journals (Sweden)

    Jeyalatha SIVARAMAKRISHNAN

    2010-01-01

    Full Text Available This paper deals with the Web Structure Mining and the different Structure Mining Algorithms like Page Rank, HITS, Trust Rank and Sel-HITS. The functioning of these algorithms are discussed. An incremental algorithm for calculation of PageRank using an interface has been formulated. This algorithm makes use of Web Link Attributes Information as key parameters and has been implemented using Visibility and Position of a Link. The application of Web Structure Mining Algorithm in an Academic Search Application has been discussed. The present work can be a useful input to Web Users, Faculty, Students and Web Administrators in a University Environment.

  7. DC Link Current Estimation in Wind-Double Feed Induction Generator Power Conditioning System

    Directory of Open Access Journals (Sweden)

    MARIAN GAICEANU

    2010-12-01

    Full Text Available In this paper the implementation of the DC link current estimator in power conditioning system of the variable speed wind turbine is shown. The wind turbine is connected to double feed induction generator (DFIG. The variable electrical energy parameters delivered by DFIG are fitted with the electrical grid parameters through back-to-back power converter. The bidirectional AC-AC power converter covers a wide speed range from subsynchronous to supersynchronous speeds. The modern control of back-to-back power converter involves power balance concept, therefore its load power should be known in any instant. By using the power balance control, the DC link voltage variation at the load changes can be reduced. In this paper the load power is estimated from the dc link, indirectly, through a second order DC link current estimator. The load current estimator is based on the DC link voltage and on the dc link input current of the rotor side converter. This method presents certain advantages instead of using measured method, which requires a low pass filter: no time delay, the feedforward current component has no ripple, no additional hardware, and more fast control response. Through the numerical simulation the performances of the proposed DC link output current estimator scheme are demonstrated.

  8. Students' Scientific Epistemic Beliefs, Online Evaluative Standards, and Online Searching Strategies for Science Information: The Moderating Role of Cognitive Load Experience

    Science.gov (United States)

    Hsieh, Ya-Hui; Tsai, Chin-Chung

    2014-06-01

    The purpose of this study is to examine the moderating role of cognitive load experience between students' scientific epistemic beliefs and information commitments, which refer to online evaluative standards and online searching strategies. A total of 344 science-related major students participated in this study. Three questionnaires were used to ascertain the students' scientific epistemic beliefs, information commitments, and cognitive load experience. Structural equation modeling was then used to analyze the moderating effect of cognitive load, with the results revealing its significant moderating effect. The relationships between sophisticated scientific epistemic beliefs and the advanced evaluative standards used by the students were significantly stronger for low than for high cognitive load students. Moreover, considering the searching strategies that the students used, the relationships between sophisticated scientific epistemic beliefs and advanced searching strategies were also stronger for low than for high cognitive load students. However, for the high cognitive load students, only one of the sophisticated scientific epistemic belief dimensions was found to positively associate with advanced evaluative standard dimensions.

  9. Design and Development of a Linked Open Data-Based Health Information Representation and Visualization System: Potentials and Preliminary Evaluation

    Science.gov (United States)

    Kauppinen, Tomi; Keßler, Carsten; Fritz, Fleur

    2014-01-01

    Background Healthcare organizations around the world are challenged by pressures to reduce cost, improve coordination and outcome, and provide more with less. This requires effective planning and evidence-based practice by generating important information from available data. Thus, flexible and user-friendly ways to represent, query, and visualize health data becomes increasingly important. International organizations such as the World Health Organization (WHO) regularly publish vital data on priority health topics that can be utilized for public health policy and health service development. However, the data in most portals is displayed in either Excel or PDF formats, which makes information discovery and reuse difficult. Linked Open Data (LOD)—a new Semantic Web set of best practice of standards to publish and link heterogeneous data—can be applied to the representation and management of public level health data to alleviate such challenges. However, the technologies behind building LOD systems and their effectiveness for health data are yet to be assessed. Objective The objective of this study is to evaluate whether Linked Data technologies are potential options for health information representation, visualization, and retrieval systems development and to identify the available tools and methodologies to build Linked Data-based health information systems. Methods We used the Resource Description Framework (RDF) for data representation, Fuseki triple store for data storage, and Sgvizler for information visualization. Additionally, we integrated SPARQL query interface for interacting with the data. We primarily use the WHO health observatory dataset to test the system. All the data were represented using RDF and interlinked with other related datasets on the Web of Data using Silk—a link discovery framework for Web of Data. A preliminary usability assessment was conducted following the System Usability Scale (SUS) method. Results We developed an LOD

  10. Design and development of a linked open data-based health information representation and visualization system: potentials and preliminary evaluation.

    Science.gov (United States)

    Tilahun, Binyam; Kauppinen, Tomi; Keßler, Carsten; Fritz, Fleur

    2014-10-25

    Healthcare organizations around the world are challenged by pressures to reduce cost, improve coordination and outcome, and provide more with less. This requires effective planning and evidence-based practice by generating important information from available data. Thus, flexible and user-friendly ways to represent, query, and visualize health data becomes increasingly important. International organizations such as the World Health Organization (WHO) regularly publish vital data on priority health topics that can be utilized for public health policy and health service development. However, the data in most portals is displayed in either Excel or PDF formats, which makes information discovery and reuse difficult. Linked Open Data (LOD)-a new Semantic Web set of best practice of standards to publish and link heterogeneous data-can be applied to the representation and management of public level health data to alleviate such challenges. However, the technologies behind building LOD systems and their effectiveness for health data are yet to be assessed. The objective of this study is to evaluate whether Linked Data technologies are potential options for health information representation, visualization, and retrieval systems development and to identify the available tools and methodologies to build Linked Data-based health information systems. We used the Resource Description Framework (RDF) for data representation, Fuseki triple store for data storage, and Sgvizler for information visualization. Additionally, we integrated SPARQL query interface for interacting with the data. We primarily use the WHO health observatory dataset to test the system. All the data were represented using RDF and interlinked with other related datasets on the Web of Data using Silk-a link discovery framework for Web of Data. A preliminary usability assessment was conducted following the System Usability Scale (SUS) method. We developed an LOD-based health information representation, querying

  11. Do inflation-linked bonds contain information about future inflation?

    Directory of Open Access Journals (Sweden)

    José Valentim Machado Vicente

    2013-06-01

    Full Text Available There is a widespread belief that inflation-linked bonds are a direct source of information about inflation expectations. In this paper we address this issue by analyzing the relationship between break-even inflation (the difference between nominal and real yields and future inflation. The dataset is extracted from Brazilian Treasury bonds covering the period from April 2005 to April 2011. We find that break-even inflation is an unbiased forecast only of the 3-month and 6-month ahead inflation. For medium horizons (12 and 18 months, break-even inflation has weak explanatory power of future inflation. Over long horizons (24 and 30 months, we report a significant, but counterintuitive, negative relationship between the break-even and realized inflation rates.

  12. Japan Link Center (JaLC): link management and DOI assignment for Japanese electronic scholarly contents

    Science.gov (United States)

    Kato, Takafumi; Tsuchiya, Eri; Kubota, Soichi; Miyagawa, Yoshiyuki

    JST, cooperated with several national institutes, is currently developing “Japan Link Center”, which manages Japanese electronic scholarly contents (journal articles, books, dissertations etc.) in an integrated fashion using Digital Object Identifier (DOI). Japan Link Center will manage metadata and whereabouts information of the contents in the digital environment and provide domestic and international linking information, cite/cited information to activate dissemination of S&T information, furthermore, to strengthen transmission of S&T information from Japan. Japan Link Center is expected to be appointed as the 9th DOI registration agency (RA) in the world by the International DOI Foundation (IDF) this spring.

  13. Biomechanical Comparison of Standard and Linked Single-Row Rotator Cuff Repairs in a Human Cadaver Model.

    Science.gov (United States)

    Meisel, Adam F; Henninger, Heath B; Barber, F Alan; Getelman, Mark H

    2017-05-01

    The purpose of this study was to evaluate the time zero cyclic and failure loading properties of a linked single-row rotator cuff repair compared with a standard simple suture single-row repair using triple-loaded suture anchors. Eighteen human cadaveric shoulders from 9 matched pairs were dissected, and full-thickness supraspinatus tears were created. The tendon cross-sectional area was recorded. In each pair, one side was repaired with a linked single-row construct and the other with a simple suture single-row construct, both using 2 triple-loaded suture anchors. After preloading, specimens were cycled to 1 MPa of effective stress at 1 Hz for 500 cycles, and gap formation was recorded with a digital video system. Samples were then loaded to failure, and modes of failure were recorded. There was no statistical difference in peak gap formation between the control and linked constructs (3.6 ± 0.9 mm and 3.6 ± 1.2 mm, respectively; P = .697). Both constructs averaged below a 5-mm cyclic failure threshold. There was no statistical difference in ultimate load to failure between the control and linked repair (511.1 ± 139.0 N and 561.2 ± 131.8 N, respectively; P = .164), and both groups reached failure at loads similar to previous studies. Constructs failed predominantly via tissue tearing parallel to the medial suture line. The linked repair performed similarly to the simple single-row repair. Both constructs demonstrated high ultimate load to failure and good resistance to gap formation with cyclic loading, validating the time zero strength of both constructs in a human cadaveric model. The linked repair provided equivalent resistance to gap formation and failure loads compared with simple suture single-row repairs with triple-loaded suture anchors. This suggests that the linked repair is a simplified rip-stop configuration using the existing suture that may perform similarly to current rotator cuff repair techniques. Copyright © 2016 Arthroscopy

  14. Drug Loading and Release Behavior Depending on the Induced Porosity of Chitosan/Cellulose Multilayer Nanofilms.

    Science.gov (United States)

    Park, Sohyeon; Choi, Daheui; Jeong, Hyejoong; Heo, Jiwoong; Hong, Jinkee

    2017-10-02

    The ability to control drug loading and release is the most important feature in the development of medical devices. In this research, we prepared a functional nanocoating technology to incorporate a drug-release layer onto a desired substrate. The multilayer films were prepared using chitosan (CHI) and carboxymethyl cellulose (CMC) polysaccharides by the layer-by-layer (LbL) method. By using chemical cross-linking to change the inner structure of the assembled multilayer, we could control the extent of drug loading and release. The cross-linked multilayer film had a porous structure and enhanced water wettability. Interestingly, more of the small-molecule drug was loaded into and released from the non-cross-linked multilayer film, whereas more of the macromolecular drug was loaded into and released from the cross-linked multilayer film. These results indicate that drug loading and release can be easily controlled according to the molecular weight of the desired drug by changing the structure of the film.

  15. Load forecasting

    International Nuclear Information System (INIS)

    Mak, H.

    1995-01-01

    Slides used in a presentation at The Power of Change Conference in Vancouver, BC in April 1995 about the changing needs for load forecasting were presented. Technological innovations and population increase were said to be the prime driving forces behind the changing needs in load forecasting. Structural changes, market place changes, electricity supply planning changes, and changes in planning objectives were other factors discussed. It was concluded that load forecasting was a form of information gathering, that provided important market intelligence

  16. Foot positioning instruction, initial vertical load position and lifting technique: effects on low back loading

    OpenAIRE

    Kingma, I.; Bosch, T.; Bruins, L.; van Dieen, J.H.

    2004-01-01

    This study investigated the effects of initial load height and foot placement instruction in four lifting techniques: free, stoop (bending the back), squat (bending the knees) and a modified squat technique (bending the knees and rotating them outward). A 2D dynamic linked segment model was combined with an EMG assisted trunk muscle model to quantify kinematics and low back loading in 10 subjects performing 19 different lifting movements, using 10.5 kg boxes without handles. When lifting from...

  17. Sales-marketing interface and company performance. Is information use the missing link?

    OpenAIRE

    Keszey, Tamara

    2013-01-01

    Over the last couple of years there has been an ongoing debate on how sales managers contribute to organizational value. Direct measures between sales-marketing interface quality and company performance are compromised, as company performance is influenced by a plethora of other factors. We advocate that the use of sales information is the missing link between sales-marketing relationship quality and organizational outcomes. We propose and empirically test a model on how sales-mar...

  18. Link prediction with node clustering coefficient

    Science.gov (United States)

    Wu, Zhihao; Lin, Youfang; Wang, Jing; Gregory, Steve

    2016-06-01

    Predicting missing links in incomplete complex networks efficiently and accurately is still a challenging problem. The recently proposed Cannistrai-Alanis-Ravai (CAR) index shows the power of local link/triangle information in improving link-prediction accuracy. Inspired by the idea of employing local link/triangle information, we propose a new similarity index with more local structure information. In our method, local link/triangle structure information can be conveyed by clustering coefficient of common-neighbors directly. The reason why clustering coefficient has good effectiveness in estimating the contribution of a common-neighbor is that it employs links existing between neighbors of a common-neighbor and these links have the same structural position with the candidate link to this common-neighbor. In our experiments, three estimators: precision, AUP and AUC are used to evaluate the accuracy of link prediction algorithms. Experimental results on ten tested networks drawn from various fields show that our new index is more effective in predicting missing links than CAR index, especially for networks with low correlation between number of common-neighbors and number of links between common-neighbors.

  19. Information literacy progression within the Environmental science program at Linköping University

    Directory of Open Access Journals (Sweden)

    Kajsa Gustafsson Åman

    2013-12-01

    Full Text Available Since the Environmental Science program at Linköping University started 1998 the author has been liaison librarian. The program is a three-year candidate program with approximately 60 students enrolled per year. Information literacy is of vital importance for the teachers and the students. Collaboration between the liaison librarian, the teachers and the administrator is the fundament. During the years a curriculum for Information literacy has evolved. The initiative for the evolvement comes from both librarian and teachers. The program consists today of fifteen different parts with education in information literacy with a progression during the three-year program. Special concern is given to progression, learning design, learning environments and quality development. An important part is appendixes in connection to the student essay. The appendixes consist of reflections on the search of information for the essay in order to make the students more conscious about their Information Literacy processes.

  20. Alaska Village Electric Load Calculator

    Energy Technology Data Exchange (ETDEWEB)

    Devine, M.; Baring-Gould, E. I.

    2004-10-01

    As part of designing a village electric power system, the present and future electric loads must be defined, including both seasonal and daily usage patterns. However, in many cases, detailed electric load information is not readily available. NREL developed the Alaska Village Electric Load Calculator to help estimate the electricity requirements in a village given basic information about the types of facilities located within the community. The purpose of this report is to explain how the load calculator was developed and to provide instructions on its use so that organizations can then use this model to calculate expected electrical energy usage.

  1. Impaired sleep and allostatic load

    DEFF Research Database (Denmark)

    Clark, Alice Jessie; Dich, Nadya; Lange, Theis

    2014-01-01

    Objective: Understanding the mechanisms linking sleep impairment to morbidity and mortality is important for future prevention, but these mechanisms are far from elucidated. We aimed to determine the relation between impaired sleep, both in terms of duration and disturbed sleep, and allostatic load...... Biobank with comprehensive information on sleep duration, disturbed sleep, objective measures of an extensive range of biological risk markers, and physical conditions. Results: Long sleep (mean difference 0.23; 95% confidence interval, 0.13, 0.32) and disturbed sleep (0.14; 0.06, 0.22) were associated...... with higher AL as well as with high-risk levels of risk markers from the anthropometric, metabolic, and immune system. Sub-analyses suggested that the association between disturbed sleep and AL might be explained by underlying disorders. Whereas there was no association between short sleep and AL...

  2. Pay-load Estimation of a 2 DOF Flexible Link Robot

    DEFF Research Database (Denmark)

    Poulsen, Niels Kjølstad; Ravn, Ole

    2005-01-01

    . Although the applied principle might be general in nature, the pa-per is applied to the well-known problem of identifying a pay-load of a moving flexible robot. This problem is almost impossible to solve by measurements, so an estimation technique must be applied. The presented method benefits from...

  3. Vocal acoustic analysis as a biometric indicator of information processing: implications for neurological and psychiatric disorders.

    Science.gov (United States)

    Cohen, Alex S; Dinzeo, Thomas J; Donovan, Neila J; Brown, Caitlin E; Morrison, Sean C

    2015-03-30

    Vocal expression reflects an integral component of communication that varies considerably within individuals across contexts and is disrupted in a range of neurological and psychiatric disorders. There is reason to suspect that variability in vocal expression reflects, in part, the availability of "on-line" resources (e.g., working memory, attention). Thus, understanding vocal expression is a potentially important biometric index of information processing, not only across but within individuals over time. A first step in this line of research involves establishing a link between vocal expression and information processing systems in healthy adults. The present study employed a dual attention experimental task where participants provided natural speech while simultaneously engaged in a baseline, medium or high nonverbal processing-load task. Objective, automated, and computerized analysis was employed to measure vocal expression in 226 adults. Increased processing load resulted in longer pauses, fewer utterances, greater silence overall and less variability in frequency and intensity levels. These results provide compelling evidence of a link between information processing resources and vocal expression, and provide important information for the development of an automated, inexpensive and uninvasive biometric measure of information processing. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  4. Nitrogen critical loads using biodiversity-related critical limits

    International Nuclear Information System (INIS)

    Posch, Maximilian; Aherne, Julian; Hettelingh, Jean-Paul

    2011-01-01

    Critical loads are widely used in the effects-based assessment of emission reduction policies. While the impacts of acidification have diminished, there is increasing concern regarding the effects of nitrogen deposition on terrestrial ecosystems. In this context much attention has been focussed on empirical critical loads as well as simulations with linked geochemistry-vegetation models. Surprisingly little attention has been paid to adapt the widely used simple mass balance approach. This approach has the well-established benefit of easy regional applicability, while incorporating specified critical chemical criteria to protect specified receptors. As plant occurrence/biodiversity is related to both the nutrient and acidity status of an ecosystem, a single abiotic factor (chemical criterion) is not sufficient. Rather than an upper limit for deposition (i.e., critical load), linked nutrient nitrogen and acidity chemical criteria for plant occurrence result in an 'optimal' nitrogen and sulphur deposition envelope. - Highlights: → Mass balance critical load approaches for nutrient nitrogen remain useful. → Biodiversity-related limits are related to nutrient and acidity status. → Nutrient and acidity chemical criteria lead to optimal deposition envelopes. → Optimal loads support effects-based emission reduction policies. - Biodiversity-related critical limits lead to optimal nitrogen and sulphur deposition envelopes for plant species or species compositions.

  5. Extracting Macroscopic Information from Web Links.

    Science.gov (United States)

    Thelwall, Mike

    2001-01-01

    Discussion of Web-based link analysis focuses on an evaluation of Ingversen's proposed external Web Impact Factor for the original use of the Web, namely the interlinking of academic research. Studies relationships between academic hyperlinks and research activities for British universities and discusses the use of search engines for Web link…

  6. Neural activity, neural connectivity, and the processing of emotionally valenced information in older adults: links with life satisfaction.

    Science.gov (United States)

    Waldinger, Robert J; Kensinger, Elizabeth A; Schulz, Marc S

    2011-09-01

    This study examines whether differences in late-life well-being are linked to how older adults encode emotionally valenced information. Using fMRI with 39 older adults varying in life satisfaction, we examined how viewing positive and negative images would affect activation and connectivity of an emotion-processing network. Participants engaged most regions within this network more robustly for positive than for negative images, but within the PFC this effect was moderated by life satisfaction, with individuals higher in satisfaction showing lower levels of activity during the processing of positive images. Participants high in satisfaction showed stronger correlations among network regions-particularly between the amygdala and other emotion processing regions-when viewing positive, as compared with negative, images. Participants low in satisfaction showed no valence effect. Findings suggest that late-life satisfaction is linked with how emotion-processing regions are engaged and connected during processing of valenced information. This first demonstration of a link between neural recruitment and late-life well-being suggests that differences in neural network activation and connectivity may account for the preferential encoding of positive information seen in some older adults.

  7. Linked Data for Fighting Global Hunger:Experiences in setting standards for Agricultural Information Management

    Science.gov (United States)

    Baker, Thomas; Keizer, Johannes

    FAO, the Food and Agriculture Organization of the UN, has the global goal to defeat hunger and eliminate poverty. One of its core functions is the generation, dissemination and application of information and knowledge. Since 2000, the Agricultural InformationManagement Standards (AIMS) activity in FAO's Knowledge Exchange and Capacity Building Division has promoted the use of Semantic Web standards to improve information sharing within a global network of research institutes and related partner organizations. The strategy emphasizes the use of simple descriptive metadata, thesauri, and ontologies for integrating access to information from a wide range of sources for both scientific and non-expert audiences. An early adopter of Semantic Web technology, the AIMS strategy is evolving to help information providers in nineteen language areas use modern Linked Data methods to improve the quality of life in developing rural areas, home to seventy percent of the world's poor and hungry people.

  8. Foot positioning instruction, initial vertical load position and lifting technique: effects on low back loading

    NARCIS (Netherlands)

    Kingma, I.; Bosch, T.; Bruins, L.; van Dieen, J.H.

    2004-01-01

    This study investigated the effects of initial load height and foot placement instruction in four lifting techniques: free, stoop (bending the back), squat (bending the knees) and a modified squat technique (bending the knees and rotating them outward). A 2D dynamic linked segment model was combined

  9. The Coordination Dynamics of Observational Learning: Relative Motion Direction and Relative Phase as Informational Content Linking Action-Perception to Action-Production.

    Science.gov (United States)

    Buchanan, John J

    2016-01-01

    The primary goal of this chapter is to merge together the visual perception perspective of observational learning and the coordination dynamics theory of pattern formation in perception and action. Emphasis is placed on identifying movement features that constrain and inform action-perception and action-production processes. Two sources of visual information are examined, relative motion direction and relative phase. The visual perception perspective states that the topological features of relative motion between limbs and joints remains invariant across an actor's motion and therefore are available for pickup by an observer. Relative phase has been put forth as an informational variable that links perception to action within the coordination dynamics theory. A primary assumption of the coordination dynamics approach is that environmental information is meaningful only in terms of the behavior it modifies. Across a series of single limb tasks and bimanual tasks it is shown that the relative motion and relative phase between limbs and joints is picked up through visual processes and supports observational learning of motor skills. Moreover, internal estimations of motor skill proficiency and competency are linked to the informational content found in relative motion and relative phase. Thus, the chapter links action to perception and vice versa and also links cognitive evaluations to the coordination dynamics that support action-perception and action-production processes.

  10. A novel grooming algorithm with the adaptive weight and load balancing for dynamic holding-time-aware traffic in optical networks

    Science.gov (United States)

    Xu, Zhanqi; Huang, Jiangjiang; Zhou, Zhiqiang; Ding, Zhe; Ma, Tao; Wang, Junping

    2013-10-01

    To maximize the resource utilization of optical networks, the dynamic traffic grooming, which could efficiently multiplex many low-speed services arriving dynamically onto high-capacity optical channels, has been studied extensively and used widely. However, the link weights in the existing research works can be improved since they do not adapt to the network status and load well. By exploiting the information on the holding times of the preexisting and new lightpaths, and the requested bandwidth of a user service, this paper proposes a grooming algorithm using Adaptively Weighted Links for Holding-Time-Aware (HTA) (abbreviated as AWL-HTA) traffic, especially in the setup process of new lightpath(s). Therefore, the proposed algorithm can not only establish a lightpath that uses network resource efficiently, but also achieve load balancing. In this paper, the key issues on the link weight assignment and procedure within the AWL-HTA are addressed in detail. Comprehensive simulation and experimental results show that the proposed algorithm has a much lower blocking ratio and latency than other existing algorithms.

  11. New Center Links Earth, Space, and Information Sciences

    Science.gov (United States)

    Aswathanarayana, U.

    2004-05-01

    Broad-based geoscience instruction melding the Earth, space, and information technology sciences has been identified as an effective way to take advantage of the new jobs created by technological innovations in natural resources management. Based on this paradigm, the University of Hyderabad in India is developing a Centre of Earth and Space Sciences that will be linked to the university's super-computing facility. The proposed center will provide the basic science underpinnings for the Earth, space, and information technology sciences; develop new methodologies for the utilization of natural resources such as water, soils, sediments, minerals, and biota; mitigate the adverse consequences of natural hazards; and design innovative ways of incorporating scientific information into the legislative and administrative processes. For these reasons, the ethos and the innovatively designed management structure of the center would be of particular relevance to the developing countries. India holds 17% of the world's human population, and 30% of its farm animals, but only about 2% of the planet's water resources. Water will hence constitute the core concern of the center, because ecologically sustainable, socially equitable, and economically viable management of water resources of the country holds the key to the quality of life (drinking water, sanitation, and health), food security, and industrial development of the country. The center will be focused on interdisciplinary basic and pure applied research that is relevant to the practical needs of India as a developing country. These include, for example, climate prediction, since India is heavily dependent on the monsoon system, and satellite remote sensing of soil moisture, since agriculture is still a principal source of livelihood in India. The center will perform research and development in areas such as data assimilation and validation, and identification of new sensors to be mounted on the Indian meteorological

  12. An NFC on Two-Coil WPT Link for Implantable Biomedical Sensors under Ultra-Weak Coupling.

    Science.gov (United States)

    Gong, Chen; Liu, Dake; Miao, Zhidong; Wang, Wei; Li, Min

    2017-06-11

    The inductive link is widely used in implantable biomedical sensor systems to achieve near-field communication (NFC) and wireless power transfer (WPT). However, it is tough to achieve reliable NFC on an inductive WPT link when the coupling coefficient is ultra-low (0.01 typically), since the NFC signal (especially for the uplink from the in-body part to the out-body part) could be too weak to be detected. Traditional load shift keying (LSK) requires strong coupling to pass the load modulation information to the power source. Instead of using LSK, we propose a dual-carrier NFC scheme for the weak-coupled inductive link; using binary phase shift keying (BPSK) modulation, its downlink data are modulated on the power carrier (2 MHz), while its uplink data are modulated on another carrier (125 kHz). The two carriers are transferred through the same coil pair. To overcome the strong interference of the power carrier, dedicated circuits are introduced. In addition, to minimize the power transfer efficiency decrease caused by adding NFC, we optimize the inductive link circuit parameters and approach the receiver sensitivity limit. In the prototype experiments, even though the coupling coefficient is as low as 0.008, the in-body transmitter costs only 0.61 mW power carrying 10 kbps of data, and achieves a 1 × 10 - 7 bit error rate under the strong interference of WPT. This dual-carrier NFC scheme could be useful for small-sized implantable biomedical sensor applications.

  13. Software defined network architecture based research on load balancing strategy

    Science.gov (United States)

    You, Xiaoqian; Wu, Yang

    2018-05-01

    As a new type network architecture, software defined network has the key idea of separating the control place of the network from the transmission plane, to manage and control the network in a concentrated way; in addition, the network interface is opened on the control layer and the data layer, so as to achieve programmable control of the network. Considering that only the single shortest route is taken into the calculation of traditional network data flow transmission, and congestion and resource consumption caused by excessive load of link circuits are ignored, a link circuit load based flow media business QoS gurantee system is proposed in this article to divide the flow in the network into ordinary data flow and QoS flow. In this way, it supervises the link circuit load with the controller so as to calculate reasonable route rapidly and issue the flow table to the exchanger, to finish rapid data transmission. In addition, it establishes a simulation platform to acquire optimized result through simulation experiment.

  14. Radiation cross-linked carboxymethyl sago pulp hydrogels loaded with ciprofloxacin: Influence of irradiation on gel fraction, entrapped drug and in vitro release

    International Nuclear Information System (INIS)

    Lam, Yi Lyn; Muniyandy, Saravanan; Kamaruddin, Hashim; Mansor, Ahmad; Janarthanan, Pushpamalar

    2015-01-01

    Carboxymethyl sago pulp (CMSP) with 0.4 DS, viscosity 184 dl/g and molecular weight 76,000 g/mol was synthesized from sago waste. 10 and 20% w/v solutions of CMSP were irradiated at 10–30 kGy to form hydrogels and were characterized by % gel fraction (GF). Irradiation of 20% CMSP using 25 kGy has produced stable hydrogels with the highest % GF and hence loaded with ciprofloxacin HCl. Drug-loaded hydrogels were produced by irradiating the mixture of drug and 20% CMSP solution at 25 kGy. After irradiation, the hydrogels were cut into circular discs with a diameter of 6±1 mm and evaluated for physicochemical properties as well as drug release kinetics. The ciprofloxacin loading in the disc was 14.7%±1 w/w with an entrapment efficiency of 73.5% w/w. The low standard deviation of drug-loaded discs indicated uniform thickness (1.5±0.3 mm). The unloaded discs were thinner (1±0.4 mm) and more brittle than the drug-loaded discs. FESEM, FT-IR, XRD, DSC and TGA analysis revealed the absence of polymer–drug interaction and transformation of crystalline to amorphous form of ciprofloxacin in the discs. The disc sustained the drug release in phosphate buffer pH 7.4 over 36 h in a first-order manner. The mechanism of the drug release was found to be swelling controlled diffusion and matrix erosion. The anti-bacterial effect of ciprofloxacin was retained after irradiation and CMSP disc could be a promising device for ocular drug delivery. - Highlights: • Carboxymethyl sago pulp (CMSP) with ciprofloxacin is irradiated to form hydrogels. • 20% CMSP at 25 kGy has produced stable hydrogels with the highest gel fraction. • Crystalline ciprofloxacin converted as amorphous during hydrogel formation. • Hydrogel in disc form sustained the drug release drug up to 36 h. • Irradiation cross-linked polymeric chain of CMSP resulted in controlled swelling

  15. Rice DB: an Oryza Information Portal linking annotation, subcellular location, function, expression, regulation, and evolutionary information for rice and Arabidopsis.

    Science.gov (United States)

    Narsai, Reena; Devenish, James; Castleden, Ian; Narsai, Kabir; Xu, Lin; Shou, Huixia; Whelan, James

    2013-12-01

    Omics research in Oryza sativa (rice) relies on the use of multiple databases to obtain different types of information to define gene function. We present Rice DB, an Oryza information portal that is a functional genomics database, linking gene loci to comprehensive annotations, expression data and the subcellular location of encoded proteins. Rice DB has been designed to integrate the direct comparison of rice with Arabidopsis (Arabidopsis thaliana), based on orthology or 'expressology', thus using and combining available information from two pre-eminent plant models. To establish Rice DB, gene identifiers (more than 40 types) and annotations from a variety of sources were compiled, functional information based on large-scale and individual studies was manually collated, hundreds of microarrays were analysed to generate expression annotations, and the occurrences of potential functional regulatory motifs in promoter regions were calculated. A range of computational subcellular localization predictions were also run for all putative proteins encoded in the rice genome, and experimentally confirmed protein localizations have been collated, curated and linked to functional studies in rice. A single search box allows anything from gene identifiers (for rice and/or Arabidopsis), motif sequences, subcellular location, to keyword searches to be entered, with the capability of Boolean searches (such as AND/OR). To demonstrate the utility of Rice DB, several examples are presented including a rice mitochondrial proteome, which draws on a variety of sources for subcellular location data within Rice DB. Comparisons of subcellular location, functional annotations, as well as transcript expression in parallel with Arabidopsis reveals examples of conservation between rice and Arabidopsis, using Rice DB (http://ricedb.plantenergy.uwa.edu.au). © 2013 The Authors The Plant Journal © 2013 John Wiley & Sons Ltd.

  16. A Geographic Information System approach to modeling nutrient and sediment transport

    Energy Technology Data Exchange (ETDEWEB)

    Levine, D.A. [Automated Sciences Group, Inc., Oak Ridge, TN (United States); Hunsaker, C.T.; Beauchamp, J.J. [Oak Ridge National Lab., TN (United States); Timmins, S.P. [Analysas Corp., Oak Ridge, TN (United States)

    1993-02-01

    The objective of this study was to develop a water quality model to quantify nonpoint-source (NPS) pollution that uses a geographic information system (GIS) to link statistical modeling of nutrient and sediment delivery with the spatial arrangement of the parameters that drive the model. The model predicts annual nutrient and sediment loading and was developed, calibrated, and tested on 12 watersheds within the Lake Ray Roberts drainage basin in north Texas. Three physiographic regions are represented by these watersheds, and model success, as measured by the accuracy of load estimates, was compared within and across these regions.

  17. Linking Formal and Informal Science Education: A Successful Model using Libraries, Volunteers and NASA Resources

    Science.gov (United States)

    Race, M. S.; Lafayette Library; Learning Center Foundation (Lllcf)

    2011-12-01

    In these times of budget cuts, tight school schedules, and limited opportunities for student field trips and teacher professional development, it is especially difficult to expose elementary and middle school students to the latest STEM information-particularly in the space sciences. Using our library as a facilitator and catalyst, we built a volunteer-based, multi-faceted, curriculum-linked program for students and teachers in local middle schools (Grade 8) and showcased new astronomical and planetary science information using mainly NASA resources and volunteer effort. The project began with the idea of bringing free NASA photo exhibits (FETTU) to the Lafayette and Antioch Libraries for public display. Subsequently, the effort expanded by adding layers of activities that brought space and science information to teachers, students and the pubic at 5 libraries and schools in the 2 cities, one of which serves a diverse, underserved community. Overall, the effort (supported by a pilot grant from the Bechtel Foundation) included school and library based teacher workshops with resource materials; travelling space museum visits with hands-on activities (Chabot-to-Go); separate powerpoint presentations for students and adults at the library; and concurrent ancillary space-related themes for young children's programs at the library. This pilot project, based largely on the use of free government resources and online materials, demonstrated that volunteer-based, standards-linked STEM efforts can enhance curriculum at the middle school, with libraries serving a special role. Using this model, we subsequently also obtained a small NASA-Space Grant award to bring star parties and hand-on science activities to three libraries this Fall, linking with numerous Grade 5 teachers and students in two additional underserved areas of our county. It's not necessary to reinvent the wheel, you just collect the pieces and build on what you already have.

  18. Cognitive Load Theory and Complex Learning: Recent Developments and Future Directions

    NARCIS (Netherlands)

    Van Merriënboer, Jeroen; Sweller, J.

    2007-01-01

    Traditionally, Cognitive Load Theory (CLT) has focused on instructional methods to decrease extraneous cognitive load so that available cognitive resources can be fully devoted to learning. This article strengthens the cognitive base of CLT by linking cognitive processes to the processes used by

  19. Formulation and Characterization of Glutaraldehyde Cross-Linked ...

    African Journals Online (AJOL)

    ... drug/polymer ratio, volume of cross linking agent and volume of surfactant were ... The microspheres were characterized for entrapment efficiency, drug loading, ... size distribution (105 – 219 μm) and an entrapment efficiency of up to 73 %.

  20. Optimizing the Loads of multi-player online game Servers using Markov Chains

    DEFF Research Database (Denmark)

    Saeed, Aamir; Olsen, Rasmus Løvenstein; Pedersen, Jens Myrup

    2015-01-01

    that is created due to the load balancing of servers. Load balancing among servers is sensitive to correct status information. The Markov based load prediction was introduced in this paper to predict load of under-loaded servers, based on arrival (μ) and departure (λ) rates of players. The prediction based...... that need to be considered when developing load balancing algorithm, that is the reliability of the information that is shared. Simulation results show that Markov based prediction of load information performed better from the normal load status information sharing....

  1. Predicting runoff induced mass loads in urban watersheds: Linking land use and pyrethroid contamination.

    Science.gov (United States)

    Chinen, Kazue; Lau, Sim-Lin; Nonezyan, Michael; McElroy, Elizabeth; Wolfe, Becky; Suffet, Irwin H; Stenstrom, Michael K

    2016-10-01

    Pyrethroid pesticide mass loadings in the Ballona Creek Watershed were calculated using the volume-concentration method with a Geographic Information Systems (GIS) to explore potential relationships between urban land use, impervious surfaces, and pyrethroid runoff flowing into an urban stream. A calibration of the GIS volume-concentration model was performed using 2013 and 2014 wet-weather sampling data. Permethrin and lambda-cyhalothrin were detected as the highest concentrations; deltamethrin, lambda-cyhalothrin, permethrin and cyfluthrin were the most frequently detected synthetic pyrethroids. Eight neighborhoods within the watershed were highlighted as target areas based on a Weighted Overlay Analysis (WOA) in GIS. Water phase concentration of synthetic pyrethroids (SPs) were calculated from the reported usage. The need for stricter BMP and consumer product controls was identified as a possible way of reducing the detections of pyrethroids in Ballona Creek. This model has significant implications for determining mass loadings due to land use influence, and offers a flexible method to extrapolate data for a limited amount of samplings for a larger watershed, particularly for chemicals that are not subject to environmental monitoring. Offered as a simple approach to watershed management, the GIS-volume concentration model has the potential to be applied to other target pesticides and is useful for simulating different watershed scenarios. Further research is needed to compare results against other similar urban watersheds situated in mediterranean climates. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Proceedings of the Workshop on Methods & Tools for Computer Supported Collaborative Creativity Process: Linking creativity & informal learning

    NARCIS (Netherlands)

    Retalis, Symeon; Sloep, Peter

    2009-01-01

    Retalis, S., & Sloep, P. B. (Eds.) (2009). Collection of 4 symposium papers at EC-TEL 2009. Proceedings of the Workshop on Methods & Tools for Computer Supported Collaborative Creativity Process: Linking creativity & informal learning. September, 30, 2009, Nice,

  3. Relationships Between Training Load Indicators and Training Outcomes in Professional Soccer

    NARCIS (Netherlands)

    Jaspers, Arne; Brink, Michel S.; Probst, Steven G M; Frencken, Wouter G. P.; Helsen, Werner F.

    Background In professional senior soccer, training load monitoring is used to ensure an optimal workload to maximize physical fitness and prevent injury or illness. However, to date, different training load indicators are used without a clear link to training outcomes. Objective The aim of this

  4. Using web services for linking genomic data to medical information systems.

    Science.gov (United States)

    Maojo, V; Crespo, J; de la Calle, G; Barreiro, J; Garcia-Remesal, M

    2007-01-01

    To develop a new perspective for biomedical information systems, regarding the introduction of ideas, methods and tools related to the new scenario of genomic medicine. Technological aspects related to the analysis and integration of heterogeneous clinical and genomic data include mapping clinical and genetic concepts, potential future standards or the development of integrated biomedical ontologies. In this clinicomics scenario, we describe the use of Web services technologies to improve access to and integrate different information sources. We give a concrete example of the use of Web services technologies: the OntoFusion project. Web services provide new biomedical informatics (BMI) approaches related to genomic medicine. Customized workflows will aid research tasks by linking heterogeneous Web services. Two significant examples of these European Commission-funded efforts are the INFOBIOMED Network of Excellence and the Advancing Clinico-Genomic Trials on Cancer (ACGT) integrated project. Supplying medical researchers and practitioners with omics data and biologists with clinical datasets can help to develop genomic medicine. BMI is contributing by providing the informatics methods and technological infrastructure needed for these collaborative efforts.

  5. Khovanov homology of graph-links

    Energy Technology Data Exchange (ETDEWEB)

    Nikonov, Igor M [M. V. Lomonosov Moscow State University, Faculty of Mechanics and Mathematics, Moscow (Russian Federation)

    2012-08-31

    Graph-links arise as the intersection graphs of turning chord diagrams of links. Speaking informally, graph-links provide a combinatorial description of links up to mutations. Many link invariants can be reformulated in the language of graph-links. Khovanov homology, a well-known and useful knot invariant, is defined for graph-links in this paper (in the case of the ground field of characteristic two). Bibliography: 14 titles.

  6. Information Theoretical Limits of Free-Space Optical Links

    KAUST Repository

    Ansari, Imran Shafique

    2016-08-25

    Generalized fading has been an imminent part and parcel of wireless communications. It not only characterizes the wireless channel appropriately but also allows its utilization for further performance analysis of various types of wireless communication systems. Under the umbrella of generalized fading channels, a unified ergodic capacity analysis of a free-space optical (FSO) link under both types of detection techniques (i.e., intensity modulation/direct detection (IM/DD) as well as heterodyne detection) over generalized atmospheric turbulence channels that account for generalized pointing errors is presented. Specifically, unified exact closed-form expressions for the moments of the end-to-end signal-to-noise ratio (SNR) of a single link FSO transmission system are presented. Subsequently, capitalizing on these unified statistics, unified exact closed-form expressions for ergodic capacity performance metric of FSO link transmission systems is offered. Additionally, for scenarios wherein the exact closed-form solution is not possible to obtain, some asymptotic results are derived in the high SNR regime. All the presented results are verified via computer-based Monte-Carlo simulations.

  7. Unsupervised/supervised learning concept for 24-hour load forecasting

    Energy Technology Data Exchange (ETDEWEB)

    Djukanovic, M [Electrical Engineering Inst. ' Nikola Tesla' , Belgrade (Yugoslavia); Babic, B [Electrical Power Industry of Serbia, Belgrade (Yugoslavia); Sobajic, D J; Pao, Y -H [Case Western Reserve Univ., Cleveland, OH (United States). Dept. of Electrical Engineering and Computer Science

    1993-07-01

    An application of artificial neural networks in short-term load forecasting is described. An algorithm using an unsupervised/supervised learning concept and historical relationship between the load and temperature for a given season, day type and hour of the day to forecast hourly electric load with a lead time of 24 hours is proposed. An additional approach using functional link net, temperature variables, average load and last one-hour load of previous day is introduced and compared with the ANN model with one hidden layer load forecast. In spite of limited available weather variables (maximum, minimum and average temperature for the day) quite acceptable results have been achieved. The 24-hour-ahead forecast errors (absolute average) ranged from 2.78% for Saturdays and 3.12% for working days to 3.54% for Sundays. (Author)

  8. A Dynamic Calibration Method for Experimental and Analytical Hub Load Comparison

    Science.gov (United States)

    2017-03-01

    computed at various pitch angles through changes in actuator length. The linear spring stiffness was estimated by using the internal volume of the...Vehicle Technology Directorate Mechanics Division (ATTN: RDRL-VTM) Aberdeen Proving Ground, MD 21005-5066 8. PERFORMING ORGANIZATION REPORT NUMBER...Finally, the balance loads are not only induced by the rotor hub loads, but also by loads transmitted via the pitch links to the swashplate. Thus

  9. An NFC on Two-Coil WPT Link for Implantable Biomedical Sensors under Ultra-Weak Coupling

    Directory of Open Access Journals (Sweden)

    Chen Gong

    2017-06-01

    Full Text Available The inductive link is widely used in implantable biomedical sensor systems to achieve near-field communication (NFC and wireless power transfer (WPT. However, it is tough to achieve reliable NFC on an inductive WPT link when the coupling coefficient is ultra-low (0.01 typically, since the NFC signal (especially for the uplink from the in-body part to the out-body part could be too weak to be detected. Traditional load shift keying (LSK requires strong coupling to pass the load modulation information to the power source. Instead of using LSK, we propose a dual-carrier NFC scheme for the weak-coupled inductive link; using binary phase shift keying (BPSK modulation, its downlink data are modulated on the power carrier (2 MHz, while its uplink data are modulated on another carrier (125 kHz. The two carriers are transferred through the same coil pair. To overcome the strong interference of the power carrier, dedicated circuits are introduced. In addition, to minimize the power transfer efficiency decrease caused by adding NFC, we optimize the inductive link circuit parameters and approach the receiver sensitivity limit. In the prototype experiments, even though the coupling coefficient is as low as 0.008, the in-body transmitter costs only 0.61 mW power carrying 10 kbps of data, and achieves a 1 × 10 - 7 bit error rate under the strong interference of WPT. This dual-carrier NFC scheme could be useful for small-sized implantable biomedical sensor applications.

  10. An NFC on Two-Coil WPT Link for Implantable Biomedical Sensors under Ultra-Weak Coupling

    Science.gov (United States)

    Gong, Chen; Liu, Dake; Miao, Zhidong; Wang, Wei; Li, Min

    2017-01-01

    The inductive link is widely used in implantable biomedical sensor systems to achieve near-field communication (NFC) and wireless power transfer (WPT). However, it is tough to achieve reliable NFC on an inductive WPT link when the coupling coefficient is ultra-low (0.01 typically), since the NFC signal (especially for the uplink from the in-body part to the out-body part) could be too weak to be detected. Traditional load shift keying (LSK) requires strong coupling to pass the load modulation information to the power source. Instead of using LSK, we propose a dual-carrier NFC scheme for the weak-coupled inductive link; using binary phase shift keying (BPSK) modulation, its downlink data are modulated on the power carrier (2 MHz), while its uplink data are modulated on another carrier (125 kHz). The two carriers are transferred through the same coil pair. To overcome the strong interference of the power carrier, dedicated circuits are introduced. In addition, to minimize the power transfer efficiency decrease caused by adding NFC, we optimize the inductive link circuit parameters and approach the receiver sensitivity limit. In the prototype experiments, even though the coupling coefficient is as low as 0.008, the in-body transmitter costs only 0.61 mW power carrying 10 kbps of data, and achieves a 1 × 10−7 bit error rate under the strong interference of WPT. This dual-carrier NFC scheme could be useful for small-sized implantable biomedical sensor applications. PMID:28604610

  11. Tipping diffusivity in information accumulation systems: more links, less consensus

    International Nuclear Information System (INIS)

    Shin, J K; Lorenz, J

    2010-01-01

    Assume two different communities each of which maintain their respective opinions mainly because of the weak interaction between them. In such a case, it is an interesting problem to find the necessary strength of inter-community interaction in order for the two communities to reach a consensus. In this paper, the information accumulation system (IAS) model is applied to investigate the problem. With the application of the IAS model, the opinion dynamics of the two-community problem is found to belong to a wider class of two-species problems appearing in population dynamics or in the competition of two languages, for all of which the governing equations can be described in terms of coupled logistic maps. Tipping diffusivity is defined as the maximal inter-community interaction such that the two communities maintain different opinions. For a problem with a simple community structure and homogeneous individuals, the tipping diffusivity is calculated theoretically. As a conclusion of the paper, the convergence of the two communities to the same value is less possible the more overall interaction, intra-community and inter-community, takes place. This implies, for example, that the increase in the interaction between individuals caused by the development of modern communication tools, such as Facebook and Twitter, does not necessarily improve the tendency towards global convergence between different communities. If the number of internal links increases by a factor, the number of inter-community links must be increased by an even higher factor, in order for consensus to be the only stable attractor

  12. Tipping diffusivity in information accumulation systems: more links, less consensus

    Energy Technology Data Exchange (ETDEWEB)

    Shin, J K [School of Mechanical Engineering, Yeungnam University, Kyongsan (Korea, Republic of); Lorenz, J [Chair of Systems Design, ETH Zurich, Kreuzplatz 5, 8032 Zürich (Switzerland)

    2010-06-01

    Assume two different communities each of which maintain their respective opinions mainly because of the weak interaction between them. In such a case, it is an interesting problem to find the necessary strength of inter-community interaction in order for the two communities to reach a consensus. In this paper, the information accumulation system (IAS) model is applied to investigate the problem. With the application of the IAS model, the opinion dynamics of the two-community problem is found to belong to a wider class of two-species problems appearing in population dynamics or in the competition of two languages, for all of which the governing equations can be described in terms of coupled logistic maps. Tipping diffusivity is defined as the maximal inter-community interaction such that the two communities maintain different opinions. For a problem with a simple community structure and homogeneous individuals, the tipping diffusivity is calculated theoretically. As a conclusion of the paper, the convergence of the two communities to the same value is less possible the more overall interaction, intra-community and inter-community, takes place. This implies, for example, that the increase in the interaction between individuals caused by the development of modern communication tools, such as Facebook and Twitter, does not necessarily improve the tendency towards global convergence between different communities. If the number of internal links increases by a factor, the number of inter-community links must be increased by an even higher factor, in order for consensus to be the only stable attractor.

  13. When interference helps: Increasing executive load to facilitate deception detection in the Concealed Information Test

    Directory of Open Access Journals (Sweden)

    George eVisu-Petra

    2013-03-01

    Full Text Available The possibility to enhance the detection efficiency of the Concealed Information Test (CIT by increasing executive load was investigated, using an interference design. After learning and executing a mock crime scenario, subjects underwent three deception detection tests: an RT-based CIT, an RT-based CIT plus a concurrent memory task (CITMem, and an RT-based CIT plus a concurrent set-shifting task (CITShift. The concealed information effect, consisting in increased RT and lower response accuracy for probe items compared to irrelevant items, was evidenced across all three conditions. The group analyses indicated a larger difference between RTs to probe and irrelevant items in the dual-task conditions, but this difference was not translated in a significantly increased detection efficiency at an individual level. Signal detection parameters based on the comparison with a simulated innocent group showed accurate discrimination for all conditions. Overall response accuracy on the CITMem was highest and the difference between response accuracy to probes and irrelevants was smallest in this condition. Accuracy on the concurrent tasks (Mem and Shift was high, and responses on these tasks were significantly influenced by CIT stimulus type (probes vs. irrelevants. The findings are interpreted in relation to the cognitive load/dual-task interference literature, generating important insights for research on the involvement of executive functions in deceptive behavior.

  14. Time- & Load-Dependence of Triboelectric Effect.

    Science.gov (United States)

    Pan, Shuaihang; Yin, Nian; Zhang, Zhinan

    2018-02-06

    Time- and load-dependent friction behavior is considered as important for a long time, due to its time-evolution and force-driving characteristics. However, its electronic behavior, mainly considered in triboelectric effect, has almost never been given the full attention and analyses from the above point of view. In this paper, by experimenting with fcc-latticed aluminum and copper friction pairs, the mechanical and electronic behaviors of friction contacts are correlated by time and load analyses, and the behind physical understanding is provided. Most importantly, the difference of "response lag" in force and electricity is discussed, the extreme points of coefficient of friction with the increasing normal loads are observed and explained with the surface properties and dynamical behaviors (i.e. wear), and the micro and macro theories linking tribo-electricity to normal load and wear (i.e. the physical explanation between coupled electrical and mechanical phenomena) are successfully developed and tested.

  15. Fast Link Adaptation for MIMO-OFDM

    DEFF Research Database (Denmark)

    Jensen, Tobias Lindstrøm; Kant, Shashi; Wehinger, Joachim

    2010-01-01

    We investigate link-quality metrics (LQMs) based on raw bit-error-rate, effective signal-to-interference-plus-noise ratio, and mutual information (MI) for the purpose of fast link adaptation (LA) in communication systems employing orthogonal frequency-division multiplexing and multiple-input–mult......We investigate link-quality metrics (LQMs) based on raw bit-error-rate, effective signal-to-interference-plus-noise ratio, and mutual information (MI) for the purpose of fast link adaptation (LA) in communication systems employing orthogonal frequency-division multiplexing and multiple...

  16. What does germane load mean? An empirical contribution to the cognitive load theory.

    Science.gov (United States)

    Debue, Nicolas; van de Leemput, Cécile

    2014-01-01

    While over the last decades, much attention has been paid to the mental workload in the field of human computer interactions, there is still a lack of consensus concerning the factors that generate it as well as the measurement methods that could reflect workload variations. Based on the multifactorial Cognitive Load Theory (CLT), our study aims to provide some food for thought about the subjective and objective measurement that can be used to disentangle the intrinsic, extraneous, and germane load. The purpose is to provide insight into the way cognitive load can explain how users' cognitive resources are allocated in the use of hypermedia, such as an online newspaper. A two-phase experiment has been conducted on the information retention from online news stories. Phase 1 (92 participants) examined the influence of multimedia content on performance as well as the relationships between cognitive loads and cognitive absorption. In Phase 2 (36 participants), eye-tracking data were collected in order to provide reliable and objective measures. Results confirmed that performance in information retention was impacted by the presence of multimedia content such as animations and pictures. The higher number of fixations on these animations suggests that users' attention could have been attracted by them. Results showed the expected opposite relationships between germane and extraneous load, a positive association between germane load and cognitive absorption and a non-linear association between intrinsic and germane load. The trends based on eye-tracking data analysis provide some interesting findings about the relationship between longer fixations, shorter saccades and cognitive load. Some issues are raised about the respective contribution of mean pupil diameter and Index of Cognitive Activity.

  17. Nonequilibrium Chromosome Looping via Molecular Slip Links

    Science.gov (United States)

    Brackley, C. A.; Johnson, J.; Michieletto, D.; Morozov, A. N.; Nicodemi, M.; Cook, P. R.; Marenduzzo, D.

    2017-09-01

    We propose a model for the formation of chromatin loops based on the diffusive sliding of molecular slip links. These mimic the behavior of molecules like cohesin, which, along with the CTCF protein, stabilize loops which contribute to organizing the genome. By combining 3D Brownian dynamics simulations and 1D exactly solvable nonequilibrium models, we show that diffusive sliding is sufficient to account for the strong bias in favor of convergent CTCF-mediated chromosome loops observed experimentally. We also find that the diffusive motion of multiple slip links along chromatin is rectified by an intriguing ratchet effect that arises if slip links bind to the chromatin at a preferred "loading site." This emergent collective behavior favors the extrusion of loops which are much larger than the ones formed by single slip links.

  18. A Methodological Alternative to Media Comparison Studies: Linking Information Utilization Strategies and Instructional Approach in Hypermedia Learning

    OpenAIRE

    Catrambone, Richard; Gerjets, Peter; Scheiter, Katharina; Vollmann, Brigitte

    2006-01-01

    Literature reviews on hypermedia learning have yet failed to show consistent positive effects of learner-controlled nonlinear information access. We argue that a possible reason for this lack of evidence in favor of hypermedia learning results from the fact that not sufficient attention is paid to the strategies of information utilization learners deploy. The few studies that do analyze these strategies fail to link them to an instructional approach, which hampers a deeper interpretation of s...

  19. Red meat consumption and risk of cardiovascular diseases-is increased iron load a possible link?

    Science.gov (United States)

    Quintana Pacheco, Daniel A; Sookthai, Disorn; Wittenbecher, Clemens; Graf, Mirja E; Schübel, Ruth; Johnson, Theron; Katzke, Verena; Jakszyn, Paula; Kaaks, Rudolf; Kühn, Tilman

    2018-01-01

    High iron load and red meat consumption could increase the risk of cardiovascular diseases (CVDs). As red meat is the main source of heme iron, which is in turn a major determinant of increased iron load, adverse cardiometabolic effects of meat consumption could be mediated by increased iron load. The object of the study was to assess whether associations between red meat consumption and CVD risk are mediated by iron load in a population-based human study. We evaluated relations between red meat consumption, iron load (plasma ferritin), and risk of CVD in the prospective EPIC-Heidelberg Study using a case-cohort sample including a random subcohort (n = 2738) and incident cases of myocardial infarction (MI, n = 555), stroke (n = 513), and CVD mortality (n = 381). Following a 4-step mediation analysis, associations between red meat consumption and iron load, red meat consumption and CVD risk, and iron load and CVD risk were assessed by multivariable regression models before finally testing to which degree associations between red meat consumption and CVD risk were attenuated by adjustment for iron status. Red meat consumption was significantly positively associated with ferritin concentrations and MI risk [HR per 50 g daily intake: 1.18 (95% CI: 1.05, 1.33)], but no significant associations with stroke risk and CVD mortality were observed. While direct associations between ferritin concentrations and MI risk as well as CVD mortality were significant in age- and sex-adjusted Cox regression models, these associations were substantially attenuated and no longer significant after multivariable adjustment for classical CVD risk factors. Strikingly, ferritin concentrations were positively associated with a majority of classical CVD risk factors (age, male sex, alcohol intake, obesity, inflammation, and lower education). Increased ferritin concentrations may be a marker of an overall unfavorable risk factor profile rather than a mediator of greater CVD risk due to meat

  20. The Algorithm of Link Prediction on Social Network

    Directory of Open Access Journals (Sweden)

    Liyan Dong

    2013-01-01

    Full Text Available At present, most link prediction algorithms are based on the similarity between two entities. Social network topology information is one of the main sources to design the similarity function between entities. But the existing link prediction algorithms do not apply the network topology information sufficiently. For lack of traditional link prediction algorithms, we propose two improved algorithms: CNGF algorithm based on local information and KatzGF algorithm based on global information network. For the defect of the stationary of social network, we also provide the link prediction algorithm based on nodes multiple attributes information. Finally, we verified these algorithms on DBLP data set, and the experimental results show that the performance of the improved algorithm is superior to that of the traditional link prediction algorithm.

  1. Fisher Information Based Meteorological Factors Introduction and Features Selection for Short-Term Load Forecasting

    Directory of Open Access Journals (Sweden)

    Shuping Cai

    2018-03-01

    Full Text Available Weather information is an important factor in short-term load forecasting (STLF. However, for a long time, more importance has always been attached to forecasting models instead of other processes such as the introduction of weather factors or feature selection for STLF. The main aim of this paper is to develop a novel methodology based on Fisher information for meteorological variables introduction and variable selection in STLF. Fisher information computation for one-dimensional and multidimensional weather variables is first described, and then the introduction of meteorological factors and variables selection for STLF models are discussed in detail. On this basis, different forecasting models with the proposed methodology are established. The proposed methodology is implemented on real data obtained from Electric Power Utility of Zhenjiang, Jiangsu Province, in southeast China. The results show the advantages of the proposed methodology in comparison with other traditional ones regarding prediction accuracy, and it has very good practical significance. Therefore, it can be used as a unified method for introducing weather variables into STLF models, and selecting their features.

  2. Detection of the dominant direction of information flow and feedback links in densely interconnected regulatory networks

    Directory of Open Access Journals (Sweden)

    Ispolatov Iaroslav

    2008-10-01

    Full Text Available Abstract Background Finding the dominant direction of flow of information in densely interconnected regulatory or signaling networks is required in many applications in computational biology and neuroscience. This is achieved by first identifying and removing links which close up feedback loops in the original network and hierarchically arranging nodes in the remaining network. In mathematical language this corresponds to a problem of making a graph acyclic by removing as few links as possible and thus altering the original graph in the least possible way. The exact solution of this problem requires enumeration of all cycles and combinations of removed links, which, as an NP-hard problem, is computationally prohibitive even for modest-size networks. Results We introduce and compare two approximate numerical algorithms for solving this problem: the probabilistic one based on a simulated annealing of the hierarchical layout of the network which minimizes the number of "backward" links going from lower to higher hierarchical levels, and the deterministic, "greedy" algorithm that sequentially cuts the links that participate in the largest number of feedback cycles. We find that the annealing algorithm outperforms the deterministic one in terms of speed, memory requirement, and the actual number of removed links. To further improve a visual perception of the layout produced by the annealing algorithm, we perform an additional minimization of the length of hierarchical links while keeping the number of anti-hierarchical links at their minimum. The annealing algorithm is then tested on several examples of regulatory and signaling networks/pathways operating in human cells. Conclusion The proposed annealing algorithm is powerful enough to performs often optimal layouts of protein networks in whole organisms, consisting of around ~104 nodes and ~105 links, while the applicability of the greedy algorithm is limited to individual pathways with ~100

  3. Load Balancing Scheme on the Basis of Huffman Coding for P2P Information Retrieval

    Science.gov (United States)

    Kurasawa, Hisashi; Takasu, Atsuhiro; Adachi, Jun

    Although a distributed index on a distributed hash table (DHT) enables efficient document query processing in Peer-to-Peer information retrieval (P2P IR), the index costs a lot to construct and it tends to be an unfair management because of the unbalanced term frequency distribution. We devised a new distributed index, named Huffman-DHT, for P2P IR. The new index uses an algorithm similar to Huffman coding with a modification to the DHT structure based on the term distribution. In a Huffman-DHT, a frequent term is assigned to a short ID and allocated a large space in the node ID space in DHT. Throuth ID management, the Huffman-DHT balances the index registration accesses among peers and reduces load concentrations. Huffman-DHT is the first approach to adapt concepts of coding theory and term frequency distribution to load balancing. We evaluated this approach in experiments using a document collection and assessed its load balancing capabilities in P2P IR. The experimental results indicated that it is most effective when the P2P system consists of about 30, 000 nodes and contains many documents. Moreover, we proved that we can construct a Huffman-DHT easily by estimating the probability distribution of the term occurrence from a small number of sample documents.

  4. Loads and loads and loads: The influence of prospective load, retrospective load, and ongoing task load in prospective memory

    Directory of Open Access Journals (Sweden)

    Beat eMeier

    2015-06-01

    Full Text Available In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load can affect prospective memory performance. The existence of multiple target events increases prospective load and adding complexity to the to-be-remembered action increases retrospective load. In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of prospective load on costs in the ongoing task for categorical targets (Experiment 2, but not for specific targets (Experiment 1. Retrospective load and ongoing task load both affected remembering the retrospective component of the prospective memory task. We suggest that prospective load can enhance costs in the ongoing task due to additional monitoring requirements. Retrospective load and ongoing task load seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially.

  5. Behavior of Shear Link of WF Section with Diagonal Web Stiffener of Eccentrically Braced Frame (EBF of Steel Structure

    Directory of Open Access Journals (Sweden)

    Yurisman

    2010-11-01

    Full Text Available This paper presents results of numerical and experimental study of shear link behavior, utilizing diagonal stiffener on web of steel profile to increase shear link performance in an eccentric braced frame (EBF of a steel structure system. The specimen is to examine the behavior of shear link by using diagonal stiffener on web part under static monotonic and cyclic load. The cyclic loading pattern conducted in the experiment is adjusted according to AISC loading standards 2005. Analysis was carried out using non-linear finite element method using MSC/NASTRAN software. Link was modeled as CQUAD shell element. Along the boundary of the loading area the nodal are constraint to produce only one direction loading. The length of the link in this analysis is 400mm of the steel profile of WF 200.100. Important parameters considered to effect significantly to the performance of shear link have been analyzed, namely flange and web thicknesses, , thickness and length of web stiffener, thickness of diagonal stiffener and geometric of diagonal stiffener. The behavior of shear link with diagonal web stiffener was compared with the behavior of standard link designed based on AISC 2005 criteria. Analysis results show that diagonal web stiffener is capable to increase shear link performance in terms of stiffness, strength and energy dissipation in supporting lateral load. However, differences in displacement ductility’s between shear links with diagonal stiffener and shear links based on AISC standards have not shown to be significant. Analysis results also show thickness of diagonal stiffener and geometric model of stiffener to have a significant influence on the performance of shear links. To perform validation of the numerical study, the research is followed by experimental work conducted in Structural Mechanic Laboratory Center for Industrial Engineering ITB. The Structures and Mechanics Lab rotary PAU-ITB. The experiments were carried out using three test

  6. Parental informal payments in Kyrgyzstani schools: Analyzing the strongest and the weakest link

    Directory of Open Access Journals (Sweden)

    Rubén Ruiz Ramas

    2016-07-01

    Full Text Available This paper aims to explain why parental informal payments emerge and then spread in different manners in Kyrgyzstani schools and to examine their interaction as informal institutions with the school as a formal one. It is argued that the main reason behind informal payments is the survival of the schools; parents' acceptance of them was a result of necessity. In a small percentage of experiences where marketization of public schools was successful, there was a socioeconomic segregation of pupils, advancing toward a de facto privatization of public schools. Then, while the key logic behind informal payments was the upgrading or elitization of schools, the nature of the engagement of givers and receivers was by choice rather than by necessity. Finally, following Helmke and Levitsky (2004, I link the survival strategy to a substitutive relationship to formal public school outcomes, and to the elitization strategy, a competing nature with the formal logic of Kyrgyzstani basic education. Special attention is given to the social function approach toward informal economy practices, and to the significance of social stratification on how those informal practices work. The paper focuses on the comparison of informal payments in two schools representing the two strategies previously described: an elitnaya school from the center of Bishkek, the 13th Gymnasium School; and the conventional 21st Middle School in the novostroika (new settlement of Enesay, the capital's periphery. The fieldwork of this research was developed in two stays during the months of July/August and October/November in 2011.

  7. Asymmetric Spatial Processing Under Cognitive Load.

    Science.gov (United States)

    Naert, Lien; Bonato, Mario; Fias, Wim

    2018-01-01

    Spatial attention allows us to selectively process information within a certain location in space. Despite the vast literature on spatial attention, the effect of cognitive load on spatial processing is still not fully understood. In this study we added cognitive load to a spatial processing task, so as to see whether it would differentially impact upon the processing of visual information in the left versus the right hemispace. The main paradigm consisted of a detection task that was performed during the maintenance interval of a verbal working memory task. We found that increasing cognitive working memory load had a more negative impact on detecting targets presented on the left side compared to those on the right side. The strength of the load effect correlated with the strength of the interaction on an individual level. The implications of an asymmetric attentional bias with a relative disadvantage for the left (vs the right) hemispace under high verbal working memory (WM) load are discussed.

  8. Asymmetric Spatial Processing Under Cognitive Load

    Directory of Open Access Journals (Sweden)

    Lien Naert

    2018-04-01

    Full Text Available Spatial attention allows us to selectively process information within a certain location in space. Despite the vast literature on spatial attention, the effect of cognitive load on spatial processing is still not fully understood. In this study we added cognitive load to a spatial processing task, so as to see whether it would differentially impact upon the processing of visual information in the left versus the right hemispace. The main paradigm consisted of a detection task that was performed during the maintenance interval of a verbal working memory task. We found that increasing cognitive working memory load had a more negative impact on detecting targets presented on the left side compared to those on the right side. The strength of the load effect correlated with the strength of the interaction on an individual level. The implications of an asymmetric attentional bias with a relative disadvantage for the left (vs the right hemispace under high verbal working memory (WM load are discussed.

  9. A sensitivity analysis approach to control of manipulators with unknown load

    International Nuclear Information System (INIS)

    Tzes, A.; Yurkovich, S.

    1987-01-01

    This paper presents a straightforward control strategy applied to an N-link manipulator holding an unknown load and driving its end effector along a prespecified trajectory. The control is constituted into two primary components. The non-adaptive component is derived from the inverse problem technique while the adaptive component is computed via the application of sensitivity analysis applied to the complete, centralized dynamic model of the manipulator. The result is a robust adaptive controller which tunes its parameters at specified time instants and can withstand all expected variations of the payload. The control synthesis is illustrated by simulations in a 2-link planar manipulator holding an unknown load

  10. Linking heterometallic rings for quantum information processing and amusement.

    Science.gov (United States)

    Timco, Grigore A; Faust, Thomas B; Tuna, Floriana; Winpenny, Richard E P

    2011-06-01

    Linking polymetallic cages can be a method for creating new structures and new properties. In this tutorial review we use heterometallic anti-ferromagnetically coupled rings (AF-rings) as exemplars for three approaches that can be used to link cage compounds. The first of three routes involves an ion-pair interaction supported by hydrogen-bonding interactions, which allows the synthesis of hybrid rotaxanes among other materials. The second route involves functionalising the exterior of the AF-ring so that it will act as a Lewis base; complexes involving coordination of pyridine to bridging monometallic and dimetallic fragments are discussed. The third route involves creating a vacancy on one site of the AF-ring, and then using the ring as a Lewis acid. Di-imine ligands can then be used to link the AF-rings into dimers. A brief discussion of the physical properties of these systems is also included.

  11. Reconstructions of information in visual spatial working memory degrade with memory load.

    Science.gov (United States)

    Sprague, Thomas C; Ester, Edward F; Serences, John T

    2014-09-22

    Working memory (WM) enables the maintenance and manipulation of information relevant to behavioral goals. Variability in WM ability is strongly correlated with IQ [1], and WM function is impaired in many neurological and psychiatric disorders [2, 3], suggesting that this system is a core component of higher cognition. WM storage is thought to be mediated by patterns of activity in neural populations selective for specific properties (e.g., color, orientation, location, and motion direction) of memoranda [4-13]. Accordingly, many models propose that differences in the amplitude of these population responses should be related to differences in memory performance [14, 15]. Here, we used functional magnetic resonance imaging and an image reconstruction technique based on a spatial encoding model [16] to visualize and quantify population-level memory representations supported by multivoxel patterns of activation within regions of occipital, parietal and frontal cortex while participants precisely remembered the location(s) of zero, one, or two small stimuli. We successfully reconstructed images containing representations of the remembered-but not forgotten-locations within regions of occipital, parietal, and frontal cortex using delay-period activation patterns. Critically, the amplitude of representations of remembered locations and behavioral performance both decreased with increasing memory load. These results suggest that differences in visual WM performance between memory load conditions are mediated by changes in the fidelity of large-scale population response profiles distributed across multiple areas of human cortex. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Materializing the web of linked data

    CERN Document Server

    Konstantinou, Nikolaos

    2015-01-01

    This book explains the Linked Data domain by adopting a bottom-up approach: it introduces the fundamental Semantic Web technologies and building blocks, which are then combined into methodologies and end-to-end examples for publishing datasets as Linked Data, and use cases that harness scholarly information and sensor data. It presents how Linked Data is used for web-scale data integration, information management and search. Special emphasis is given to the publication of Linked Data from relational databases as well as from real-time sensor data streams. The authors also trace the transformation from the document-based World Wide Web into a Web of Data. Materializing the Web of Linked Data is addressed to researchers and professionals studying software technologies, tools and approaches that drive the Linked Data ecosystem, and the Web in general.

  13. LinkED: A Novel Methodology for Publishing Linked Enterprise Data

    Directory of Open Access Journals (Sweden)

    Shreyas Suresh Rao

    2017-01-01

    Full Text Available Semantic Web technologies have redefined and strengthened the Enterprise-Web interoperability over the last decade. Linked Open Data (LOD refers to a set of best practices that empower enterprises to publish and interlink their data using existing ontologies on the World Wide Web. Current research in LOD focuses on expert search, the creation of unified information space and augmentation of core data from an enterprise context. However, existing approaches for publication of enterprise data as LOD are domain-specific, ad-hoc and suffer from lack of uniform representation across domains. The paper proposes a novel methodology called LinkED that contributes towards LOD literature in two ways: (a streamlines the publishing process through five stages of cleaning, triplification, interlinking, storage and visualization; (b addresses the latest challenges in LOD publication, namely: inadequate links, inconsistencies in the quality of the dataset and replicability of the LOD publication process. Further, the methodology is demonstrated via the publication of digital repository data as LOD in a university setting, which is evaluated based on two semantic standards: Five-Star model and data quality metrics. Overall, the paper provides a generic LOD publication process that is applicable across various domains such as healthcare, e-governance, banking, and tourism, to name a few.

  14. What does germane load mean? An empirical contribution to the cognitive load theory

    Directory of Open Access Journals (Sweden)

    Nicolas eDebue

    2014-10-01

    Full Text Available While over the last decades, much attention has been paid to the mental workload in the field of human computer interactions, there is still a lack of consensus concerning the factors that generate it as well as the measurement methods that could reflect workload variations. Based on the multifactorial Cognitive Load Theory, our study aims to provide some food for thought about the subjective and objective measurement that can be used to disentangle the intrinsic, extraneous and germane load. The purpose is to provide insight into the way cognitive load can explain how users’ cognitive resources are allocated in the use of hypermedia, such as an online newspaper. A two-phase experiment has been conducted on the information retention from online news stories. Phase 1 (92 participants examined the influence of multimedia content on performance as well as the relationships between cognitive loads and cognitive absorption. In Phase 2 (36 participants, eye-tracking data were collected in order to provide reliable and objective measures. Results confirmed that performance in information retention was impacted by the presence of multimedia content such as animations and pictures. The higher number of fixations on these animations suggests that users’ attention could have been attracted by them. Results showed the expected opposite relationships between Germane and Extraneous Load, a positive association between GL and cognitive absorption and a nonlinear association between Intrinsic and Germane Load. The trends based on eye-tracking data analysis provide some interesting findings about the relationships between longer fixations, shorter saccades and cognitive load. Some issues are raised about the respective contribution of mean pupil diameter and Index of Cognitive Activity.

  15. Reflecting the real value of health care resources in modelling and cost-effectiveness studies-The example of viral load informed differentiated care.

    Science.gov (United States)

    Revill, Paul; Walker, Simon; Cambiano, Valentina; Phillips, Andrew; Sculpher, Mark J

    2018-01-01

    The WHO HIV Treatment Guidelines suggest routine viral-load monitoring can be used to differentiate antiretroviral therapy (ART) delivery and reduce the frequency of clinic visits for patients stable on ART. This recommendation was informed by economic analysis that showed the approach is very likely to be cost-effective, even in the most resource constrained of settings. The health benefits were shown to be modest but the costs of introducing and scaling up viral load monitoring can be offset by anticipated reductions in the costs of clinic visits, due to these being less frequent for many patients. The cost-effectiveness of introducing viral-load informed differentiated care depends upon whether cost reductions are possible if the number of clinic visits is reduced and/or how freed clinic capacity is used for alternative priorities. Where freed resources, either physical or financial, generate large health gains (e.g. if committed to patients failing ART or to other high value health care interventions), the benefits of differentiated care are expected to be high; if however these freed physical resources are already under-utilized or financial resources are used less efficiently and would not be put to as beneficial an alternative use, the policy may not be cost-effective. The implication is that the use of conventional unit costs to value resources may not well reflect the latter's value in contributing to health improvement. Analyses intended to inform resource allocated decisions in a number of settings may therefore have to be interpreted with due consideration to local context. In this paper we present methods of how economic analyses can reflect the real value of health care resources rather than simply applying their unit costs. The analyses informing the WHO Guidelines are re-estimated by implementing scenarios using this framework, informing how differentiated care can be prioritized to generate greatest gains in population health. The findings have

  16. Reflecting the real value of health care resources in modelling and cost-effectiveness studies—The example of viral load informed differentiated care

    Science.gov (United States)

    Walker, Simon; Cambiano, Valentina; Phillips, Andrew; Sculpher, Mark J.

    2018-01-01

    Background The WHO HIV Treatment Guidelines suggest routine viral-load monitoring can be used to differentiate antiretroviral therapy (ART) delivery and reduce the frequency of clinic visits for patients stable on ART. This recommendation was informed by economic analysis that showed the approach is very likely to be cost-effective, even in the most resource constrained of settings. The health benefits were shown to be modest but the costs of introducing and scaling up viral load monitoring can be offset by anticipated reductions in the costs of clinic visits, due to these being less frequent for many patients. Key issues for economic evaluation The cost-effectiveness of introducing viral-load informed differentiated care depends upon whether cost reductions are possible if the number of clinic visits is reduced and/or how freed clinic capacity is used for alternative priorities. Where freed resources, either physical or financial, generate large health gains (e.g. if committed to patients failing ART or to other high value health care interventions), the benefits of differentiated care are expected to be high; if however these freed physical resources are already under-utilized or financial resources are used less efficiently and would not be put to as beneficial an alternative use, the policy may not be cost-effective. The implication is that the use of conventional unit costs to value resources may not well reflect the latter’s value in contributing to health improvement. Analyses intended to inform resource allocated decisions in a number of settings may therefore have to be interpreted with due consideration to local context. In this paper we present methods of how economic analyses can reflect the real value of health care resources rather than simply applying their unit costs. The analyses informing the WHO Guidelines are re-estimated by implementing scenarios using this framework, informing how differentiated care can be prioritized to generate greatest

  17. Critical acidity loads in France; Charges critiques d`acidite en France

    Energy Technology Data Exchange (ETDEWEB)

    Probst, A.; Party, J.P.; Fevrier, C. [Centre de Geochimie de la Surface (UPR 06251 du CNRS), 67 - Strasbourg (France); Dambrine, E. [Centre de Recherches Forestieres, INRA, 45 - Orleans (France); Thomas, A.L.; King, D. [Institut National de Recherches Agronomique (INRA), 45 - ORDON (France); Stussi, J.M. [Centre National de la Recherche Scientifique (CNRS), 54 - Vandoeuvre-les-Nancy (France)

    1997-12-31

    Based on results from several systematic forest and surface water monitoring programs, carried out in various parts of France as well as in Europe, acidity critical loads have been calculated for soils and surface waters; critical loads are presented for water and soils in crystalline mountainous regions such as Ardennes, Vosges and Massif Central; links with geochemistry, ecosystems and types of trees are discussed and perspectives are given for the calculation of acid and nitrogen critical loads on the whole France

  18. Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents.

    Science.gov (United States)

    Kim, Jong Oh; Sahay, Gaurav; Kabanov, Alexander V; Bronich, Tatiana K

    2010-04-12

    Novel functional polymeric nanocarriers with ionic cores containing biodegradable cross-links were developed for delivery of chemotherapeutic agents. Block ionomer complexes (BIC) of poly(ethylene oxide)-b-poly(methacylic acid) (PEO-b-PMA) and divalent metal cations (Ca(2+)) were utilized as templates. Disulfide bonds were introduced into the ionic cores by using cystamine as a biodegradable cross-linker. The resulting cross-linked micelles with disulfide bonds represented soft, hydrogel-like nanospheres and demonstrated a time-dependent degradation in the conditions mimicking the intracellular reducing environment. The ionic character of the cores allowed to achieve a very high level of doxorubicin (DOX) loading (50% w/w) into the cross-linked micelles. DOX-loaded degradable cross-linked micelles exhibited more potent cytotoxicity against human A2780 ovarian carcinoma cells as compared to micellar formulations without disulfide linkages. These novel biodegradable cross-linked micelles are expected to be attractive candidates for delivery of anticancer drugs.

  19. Blinded by the load: attention, awareness and the role of perceptual load.

    Science.gov (United States)

    Lavie, Nilli; Beck, Diane M; Konstantinou, Nikos

    2014-05-05

    What is the relationship between attention and conscious awareness? Awareness sometimes appears to be restricted to the contents of focused attention, yet at other times irrelevant distractors will dominate awareness. This contradictory relationship has also been reflected in an abundance of discrepant research findings leading to an enduring controversy in cognitive psychology. Lavie's load theory of attention suggests that the puzzle can be solved by considering the role of perceptual load. Although distractors will intrude upon awareness in conditions of low load, awareness will be restricted to the content of focused attention when the attended information involves high perceptual load. Here, we review recent evidence for this proposal with an emphasis on the various subjective blindness phenomena, and their neural correlates, induced by conditions of high perceptual load. We also present novel findings that clarify the role of attention in the response to stimulus contrast. Overall, this article demonstrates a critical role for perceptual load across the spectrum of perceptual processes leading to awareness, from the very early sensory responses related to contrast detection to explicit recognition of semantic content.

  20. Exploring the link between meteorological drought and streamflow to inform water resource management

    Science.gov (United States)

    Lennard, Amy; Macdonald, Neil; Hooke, Janet

    2015-04-01

    Drought indicators are an under-used metric in UK drought management. Standardised drought indicators offer a potential monitoring and management tool for operational water resource management. However, the use of these metrics needs further investigation. This work uses statistical analysis of the climatological drought signal based on meteorological drought indicators and observed streamflow data to explore the link between meteorological drought and hydrological drought to inform water resource management for a single water resource region. The region, covering 21,000 km2 of the English Midlands and central Wales, includes a variety of landscapes and climatological conditions. Analysis of the links between meteorological drought and hydrological drought performed using streamflow data from 'natural' catchments indicates a close positive relationship between meteorological drought indicators and streamflow, enhancing confidence in the application of drought indicators for monitoring and management. However, many of the catchments in the region are subject to modification through impoundments, abstractions and discharge. Therefore, it is beneficial to explore how climatological drought signal propagates into managed hydrological systems. Using a longitudinal study of catchments and sub-catchments that include natural and modified river reaches the relationship between meteorological and hydrological drought is explored. Initial statistical analysis of meteorological drought indicators and streamflow data from modified catchments shows a significantly weakened statistical relationship and reveals how anthropogenic activities may alter hydrological drought characteristics in modified catchments. Exploring how meteorological drought indicators link to streamflow across the water supply region helps build an understanding of their utility for operational water resource management.

  1. A Multi-Cycle Q-Modulation for Dynamic Optimization of Inductive Links.

    Science.gov (United States)

    Lee, Byunghun; Yeon, Pyungwoo; Ghovanloo, Maysam

    2016-08-01

    This paper presents a new method, called multi-cycle Q-modulation, which can be used in wireless power transmission (WPT) to modulate the quality factor (Q) of the receiver (Rx) coil and dynamically optimize the load impedance to maximize the power transfer efficiency (PTE) in two-coil links. A key advantage of the proposed method is that it can be easily implemented using off-the-shelf components without requiring fast switching at or above the carrier frequency, which is more suitable for integrated circuit design. Moreover, the proposed technique does not need any sophisticated synchronization between the power carrier and Q-modulation switching pulses. The multi-cycle Q-modulation is analyzed theoretically by a lumped circuit model, and verified in simulation and measurement using an off-the-shelf prototype. Automatic resonance tuning (ART) in the Rx, combined with multi-cycle Q-modulation helped maximizing PTE of the inductive link dynamically in the presence of environmental and loading variations, which can otherwise significantly degrade the PTE in multi-coil settings. In the prototype conventional 2-coil link, the proposed method increased the power amplifier (PA) plus inductive link efficiency from 4.8% to 16.5% at ( R L = 1 kΩ, d 23 = 3 cm), and from 23% to 28.2% at ( R L = 100 Ω, d 23 = 3 cm) after 11% change in the resonance capacitance, while delivering 168.1 mW to the load (PDL).

  2. Macrophyte Community Response to Nitrogen Loading and Thermal Stressors in Rapidly Flushed Mesocosm Systems

    Science.gov (United States)

    Increased nitrogen loading has been directly linked to the proliferation of planktonic and macroalgal blooms at a global scale with negative impacts on estuarine ecology and human health. Under excessive anthropogenic nutrient loads, seagrass systems can be replaced by either ma...

  3. Enhanced method of fast re-routing with load balancing in software-defined networks

    Science.gov (United States)

    Lemeshko, Oleksandr; Yeremenko, Oleksandra

    2017-11-01

    A two-level method of fast re-routing with load balancing in a software-defined network (SDN) is proposed. The novelty of the method consists, firstly, in the introduction of a two-level hierarchy of calculating the routing variables responsible for the formation of the primary and backup paths, and secondly, in ensuring a balanced load of the communication links of the network, which meets the requirements of the traffic engineering concept. The method provides implementation of link, node, path, and bandwidth protection schemes for fast re-routing in SDN. The separation in accordance with the interaction prediction principle along two hierarchical levels of the calculation functions of the primary (lower level) and backup (upper level) routes allowed to abandon the initial sufficiently large and nonlinear optimization problem by transiting to the iterative solution of linear optimization problems of half the dimension. The analysis of the proposed method confirmed its efficiency and effectiveness in terms of obtaining optimal solutions for ensuring balanced load of communication links and implementing the required network element protection schemes for fast re-routing in SDN.

  4. Maximum allowable load on wheeled mobile manipulators

    International Nuclear Information System (INIS)

    Habibnejad Korayem, M.; Ghariblu, H.

    2003-01-01

    This paper develops a computational technique for finding the maximum allowable load of mobile manipulator during a given trajectory. The maximum allowable loads which can be achieved by a mobile manipulator during a given trajectory are limited by the number of factors; probably the dynamic properties of mobile base and mounted manipulator, their actuator limitations and additional constraints applied to resolving the redundancy are the most important factors. To resolve extra D.O.F introduced by the base mobility, additional constraint functions are proposed directly in the task space of mobile manipulator. Finally, in two numerical examples involving a two-link planar manipulator mounted on a differentially driven mobile base, application of the method to determining maximum allowable load is verified. The simulation results demonstrates the maximum allowable load on a desired trajectory has not a unique value and directly depends on the additional constraint functions which applies to resolve the motion redundancy

  5. A vulnerability in Google AdSense: Automatic extraction of links to ads

    OpenAIRE

    Ochando, Manuel Blázquez

    2015-01-01

    On the basis of the XSS (Cross Site Scripting) and Web Crawler techniques it is possible to go through the barriers of the Google Adsense advertising system by obtaining the validated links of the ads published on a website. Such method involves obtaining the source code built for the Google java applet for publishing and handling ads and for the final link retrieval. Once the links of the ads have been obtained, you can use the user sessions visiting other websites to load such links, in the...

  6. Website Policies / Important Links | Data Explorer

    Science.gov (United States)

    Website Policies / Important Links Javascript Not Enabled OSTI Security Website Policies and Important ) Publication Date (oldest first) Close Clear All Find DOE Data Explorer Website Policies / Important Links Science | Office of Scientific and Technical Information Website Policies / Important Links * Site Map

  7. Information Theoretical Limits of Free-Space Optical Links

    KAUST Repository

    Ansari, Imran Shafique; Al-Quwaiee, Hessa; Zedini, Emna; Alouini, Mohamed-Slim

    2016-01-01

    detection) over generalized atmospheric turbulence channels that account for generalized pointing errors is presented. Specifically, unified exact closed-form expressions for the moments of the end-to-end signal-to-noise ratio (SNR) of a single link FSO

  8. Evaluation of a Pilot Surveillance System: Health and Environment Linked for Information Exchange in Atlanta (HELIX-Atlanta)

    Science.gov (United States)

    Meyer, P.; Shire, J.; Qualters, Judy; Daley, Randolph; Fiero, Leslie Todorov; Autry, Andy; Avchen, Rachel; Stock, Allison; Correa, Adolofo; Siffel, Csaba; hide

    2007-01-01

    CDC and its partners established the Health and Environment Linked for Information Exchange, Atlanta (HELIX-Atlanta) demonstration project, to develop linking and analysis methods that could be used by the National Environmental Public Health Tracking (EPHT) Network. Initiated in October 2003, the Metropolitan Atlanta-based collaborative conducted four projects: asthma and particulate air pollution, birth defects and ozone and particulate air pollution, childhood leukemia and traffic emissions, and children's blood lead testing and neighborhood risk factors for lead poisoning. This report provides an overview of the HELIX-Atlanta projects' goals, methods and outcomes. We discuss priority attributes and common issues and challenges and offer recommendations for implementation of the nascent national environmental public health tracking network.

  9. Adsorption of Amido Black 10B from aqueous solutions onto Zr (IV) surface-immobilized cross-linked chitosan/bentonite composite

    International Nuclear Information System (INIS)

    Zhang, Lujie; Hu, Pan; Wang, Jing; Huang, Ruihua

    2016-01-01

    Graphical abstract: - Highlights: • Zr-CCB was prepared and characterized. • The adsorption of AB10B followed the Langmuir isotherm model. • The pseudo-second-order model described the kinetic behavior. - Abstract: Zr(IV) surface-immobilized cross-linked chitosan/bentonite composite was synthesized by immersing cross-linked chitosan/bentonite composite in zirconium oxychloride solution, and characterized by X-ray diffraction, Fourier transform infrared spectroscopy, Scanning electron microscopy techniques. The adsorption of an anionic dye, Amido Black 10B, from aqueous solution by Zr(IV) loaded cross-linked chitosan/bentonite composite was investigated as a function of loading amount of Zr(IV), adsorbent dosage, pH value of initial dye solution, and ionic strength. The removal of Amido Black 10B increased with an increase in loading amount of Zr(IV) and adsorbent dosage, but decreased with an increase in pH or ionic strength. The adsorption of AB10B onto Zr(IV) loaded cross-linked chitosan/bentonite composite was favored at lower pH values and higher temperatures. The Langmuir isotherm model fitted well with the equilibrium adsorption isotherm data and the maximum monolayer adsorption capacity was 418.4 mg/g at natural pH value and 298 K. The pseudo-second-order kinetic model well described the adsorption process of Amido Black 10B onto Zr(IV) loaded cross-linked chitosan/bentonite composite. The possible mechanisms controlling Amido Black 10B adsorption included hydrogen bonding and electrostatic interactions.

  10. Adsorption of Amido Black 10B from aqueous solutions onto Zr (IV) surface-immobilized cross-linked chitosan/bentonite composite

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Lujie; Hu, Pan; Wang, Jing; Huang, Ruihua, E-mail: hrh20022002@163.com

    2016-04-30

    Graphical abstract: - Highlights: • Zr-CCB was prepared and characterized. • The adsorption of AB10B followed the Langmuir isotherm model. • The pseudo-second-order model described the kinetic behavior. - Abstract: Zr(IV) surface-immobilized cross-linked chitosan/bentonite composite was synthesized by immersing cross-linked chitosan/bentonite composite in zirconium oxychloride solution, and characterized by X-ray diffraction, Fourier transform infrared spectroscopy, Scanning electron microscopy techniques. The adsorption of an anionic dye, Amido Black 10B, from aqueous solution by Zr(IV) loaded cross-linked chitosan/bentonite composite was investigated as a function of loading amount of Zr(IV), adsorbent dosage, pH value of initial dye solution, and ionic strength. The removal of Amido Black 10B increased with an increase in loading amount of Zr(IV) and adsorbent dosage, but decreased with an increase in pH or ionic strength. The adsorption of AB10B onto Zr(IV) loaded cross-linked chitosan/bentonite composite was favored at lower pH values and higher temperatures. The Langmuir isotherm model fitted well with the equilibrium adsorption isotherm data and the maximum monolayer adsorption capacity was 418.4 mg/g at natural pH value and 298 K. The pseudo-second-order kinetic model well described the adsorption process of Amido Black 10B onto Zr(IV) loaded cross-linked chitosan/bentonite composite. The possible mechanisms controlling Amido Black 10B adsorption included hydrogen bonding and electrostatic interactions.

  11. Effects of load and maintenance duration on the time course of information encoding and retrieval in working memory: from perceptual analysis to post-categorization processes.

    Science.gov (United States)

    Pinal, Diego; Zurrón, Montserrat; Díaz, Fernando

    2014-01-01

    information encoding, maintenance, and retrieval; these are supported by brain activity in a network of frontal, parietal and temporal regions. Manipulation of WM load and duration of the maintenance period can modulate this activity. Although such modulations have been widely studied using the event-related potentials (ERP) technique, a precise description of the time course of brain activity during encoding and retrieval is still required. Here, we used this technique and principal component analysis to assess the time course of brain activity during encoding and retrieval in a delayed match to sample task. We also investigated the effects of memory load and duration of the maintenance period on ERP activity. Brain activity was similar during information encoding and retrieval and comprised six temporal factors, which closely matched the latency and scalp distribution of some ERP components: P1, N1, P2, N2, P300, and a slow wave. Changes in memory load modulated task performance and yielded variations in frontal lobe activation. Moreover, the P300 amplitude was smaller in the high than in the low load condition during encoding and retrieval. Conversely, the slow wave amplitude was higher in the high than in the low load condition during encoding, and the same was true for the N2 amplitude during retrieval. Thus, during encoding, memory load appears to modulate the processing resources for context updating and post-categorization processes, and during retrieval it modulates resources for stimulus classification and context updating. Besides, despite the lack of differences in task performance related to duration of the maintenance period, larger N2 amplitude and stronger activation of the left temporal lobe after long than after short maintenance periods were found during information retrieval. Thus, results regarding the duration of maintenance period were complex, and future work is required to test the time-based decay theory predictions.

  12. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the link between drug misuse and HIV infection. It contains information for young people, parents and teachers, ... present time. The virus (HIV) and the disease it causes (AIDS) are often linked and referred to ...

  13. Urban rainfall estimation employing commercial microwave links

    Science.gov (United States)

    Overeem, Aart; Leijnse, Hidde; Uijlenhoet, Remko; ten Veldhuis, Marie-claire

    2015-04-01

    Urban areas often lack rainfall information. To increase the number of rainfall observations in cities, microwave links from operational cellular telecommunication networks may be employed. Although this new potential source of rainfall information has been shown to be promising, its quality needs to be demonstrated more extensively. In the Rain Sense kickstart project of the Amsterdam Institute for Advanced Metropolitan Solutions (AMS), sensors and citizens are preparing Amsterdam for future weather. Part of this project is rainfall estimation using new measurement techniques. Innovative sensing techniques will be utilized such as rainfall estimation from microwave links, umbrellas for weather sensing, low-cost sensors at lamp posts and in drainage pipes for water level observation. These will be combined with information provided by citizens in an active way through smartphone apps and in a passive way through social media posts (Twitter, Flickr etc.). Sensor information will be integrated, visualized and made accessible to citizens to help raise citizen awareness of urban water management challenges and promote resilience by providing information on how citizens can contribute in addressing these. Moreover, citizens and businesses can benefit from reliable weather information in planning their social and commercial activities. In the end city-wide high-resolution rainfall maps will be derived, blending rainfall information from microwave links and weather radars. This information will be used for urban water management. This presentation focuses on rainfall estimation from commercial microwave links. Received signal levels from tens of microwave links within the Amsterdam region (roughly 1 million inhabitants) in the Netherlands are utilized to estimate rainfall with high spatial and temporal resolution. Rainfall maps will be presented and compared to a gauge-adjusted radar rainfall data set. Rainfall time series from gauge(s), radars and links will be compared.

  14. Information needs at the beginning of foraging: grass-cutting ants trade off load size for a faster return to the nest.

    Directory of Open Access Journals (Sweden)

    Martin Bollazzi

    2011-03-01

    Full Text Available Acquisition of information about food sources is essential for animals that forage collectively like social insects. Foragers deliver two commodities to the nest, food and information, and they may favor the delivery of one at the expenses of the other. We predict that information needs should be particularly high at the beginning of foraging: the decision to return faster to the nest will motivate a grass-cutting ant worker to reduce its loading time, and so to leave the source with a partial load.Field results showed that at the initial foraging phase, most grass-cutting ant foragers (Acromyrmex heyeri returned unladen to the nest, and experienced head-on encounters with outgoing workers. Ant encounters were not simply collisions in a probabilistic sense: outgoing workers contacted in average 70% of the returning foragers at the initial foraging phase, and only 20% at the established phase. At the initial foraging phase, workers cut fragments that were shorter, narrower, lighter and tenderer than those harvested at the established one. Foragers walked at the initial phase significantly faster than expected for the observed temperatures, yet not at the established phase. Moreover, when controlling for differences in the fragment-size carried, workers still walked faster at the initial phase. Despite the higher speed, their individual transport rate of vegetable tissue was lower than that of similarly-sized workers foraging later at the same patch.At the initial foraging phase, workers compromised their individual transport rates of material in order to return faster to the colony. We suggest that the observed flexible cutting rules and the selection of partial loads at the beginning of foraging are driven by the need of information transfer, crucial for the establishment and maintenance of a foraging process to monopolize a discovered resource.

  15. Review: Optimising cognitive load and usability to improve the ...

    African Journals Online (AJOL)

    Cognitive load theory views learning as involving active processing of information by working memory via separate visual and auditory channels. This system is of ... The fields of cognitive load theory and human-computer interaction share a common goal in striving to reduce extraneous cognitive load. The load induced by ...

  16. Optimal load scheduling in commercial and residential microgrids

    Science.gov (United States)

    Ganji Tanha, Mohammad Mahdi

    Residential and commercial electricity customers use more than two third of the total energy consumed in the United States, representing a significant resource of demand response. Price-based demand response, which is in response to changes in electricity prices, represents the adjustments in load through optimal load scheduling (OLS). In this study, an efficient model for OLS is developed for residential and commercial microgrids which include aggregated loads in single-units and communal loads. Single unit loads which include fixed, adjustable and shiftable loads are controllable by the unit occupants. Communal loads which include pool pumps, elevators and central heating/cooling systems are shared among the units. In order to optimally schedule residential and commercial loads, a community-based optimal load scheduling (CBOLS) is proposed in this thesis. The CBOLS schedule considers hourly market prices, occupants' comfort level, and microgrid operation constraints. The CBOLS' objective in residential and commercial microgrids is the constrained minimization of the total cost of supplying the aggregator load, defined as the microgrid load minus the microgrid generation. This problem is represented by a large-scale mixed-integer optimization for supplying single-unit and communal loads. The Lagrangian relaxation methodology is used to relax the linking communal load constraint and decompose the independent single-unit functions into subproblems which can be solved in parallel. The optimal solution is acceptable if the aggregator load limit and the duality gap are within the bounds. If any of the proposed criteria is not satisfied, the Lagrangian multiplier will be updated and a new optimal load schedule will be regenerated until both constraints are satisfied. The proposed method is applied to several case studies and the results are presented for the Galvin Center load on the 16th floor of the IIT Tower in Chicago.

  17. Bridging the gap: linking a legacy hospital information system with a filmless radiology picture archiving and communications system within a nonhomogeneous environment.

    Science.gov (United States)

    Rubin, R K; Henri, C J; Cox, R D

    1999-05-01

    A health level 7 (HL7)-conformant data link to exchange information between the mainframe hospital information system (HIS) of our hospital and our home-grown picture archiving and communications system (PACS) is a result of a collaborative effort between the HIS department and the PACS development team. Based of the ability to link examination requisitions and image studies, applications have been generated to optimise workflow and to improve the reliability and distribution of radiology information. Now, images can be routed to individual radiologists and clinicians; worklists facilitate radiology reporting; applications exist to create, edit, and view reports and images via the internet; and automated quality control now limits the incidence of "lost" cases and errors in image routing. By following the HL7 standard to develop the gateway to the legacy system, the development of a radiology information system for booking, reading, reporting, and billing remains universal and does not preclude the option to integrate off-the-shelf commercial products.

  18. The importance of link evidence in Wikipedia

    NARCIS (Netherlands)

    Kamps, J.; Koolen, M.

    2008-01-01

    Wikipedia is one of the most popular information sources on the Web. The free encyclopedia is densely linked. The link structure in Wikipedia differs from the Web at large: internal links in Wikipedia are typically based on words naturally occurring in a page, and link to another semantically

  19. Why should we publish Linked Data?

    Science.gov (United States)

    Blower, Jon; Riechert, Maik; Koubarakis, Manolis; Pace, Nino

    2016-04-01

    We use the Web every day to access information from all kinds of different sources. But the complexity and diversity of scientific data mean that discovering accessing and interpreting data remains a large challenge to researchers, decision-makers and other users. Different sources of useful information on data, algorithms, instruments and publications are scattered around the Web. How can we link all these things together to help users to better understand and exploit earth science data? How can we combine scientific data with other relevant data sources, when standards for describing and sharing data vary so widely between communities? "Linked Data" is a term that describes a set of standards and "best practices" for sharing data on the Web (http://www.w3.org/standards/semanticweb/data). These principles can be summarised as follows: 1. Create unique and persistent identifiers for the important "things" in a community (e.g. datasets, publications, algorithms, instruments). 2. Allow users to "look up" these identifiers on the web to find out more information about them. 3. Make this information machine-readable in a community-neutral format (such as RDF, Resource Description Framework). 4. Within this information, embed links to other things and concepts and say how these are related. 5. Optionally, provide web service interfaces to allow the user to perform sophisticated queries over this information (using a language such as SPARQL). The promise of Linked Data is that, through these techniques, data will be more discoverable, more comprehensible and more usable by different communities, not just the community that produced the data. As a result, many data providers (particularly public-sector institutions) are now publishing data in this way. However, this area is still in its infancy in terms of real-world applications. Data users need guidance and tools to help them use Linked Data. Data providers need reassurance that the investments they are making in

  20. Sodium Dodecyl Sulfate (SDS)-Loaded Nanoporous Polymer as Anti-Biofilm Surface Coating Material

    DEFF Research Database (Denmark)

    Li, Li; Molin, Søren; Yang, Liang

    2013-01-01

    -b-polydimethylsiloxane (1,2-PB-b-PDMS) block copolymer via chemical cross-linking of the 1,2-PB block followed by quantitative removal of the PDMS block. Sodium dodecyl sulfate (SDS) was loaded into the nanoporous 1,2-PB from aqueous solution. The SDS-loaded nanoporous polymer films were shown to block bacterial attachment...

  1. Perceptual Load Affects Eyewitness Accuracy & Susceptibility to Leading Questions

    Directory of Open Access Journals (Sweden)

    Gillian Murphy

    2016-08-01

    Full Text Available Load Theory (Lavie, 1995; 2005 states that the level of perceptual load in a task (i.e. the amount of information involved in processing task-relevant stimuli determines the efficiency of selective attention. There is evidence that perceptual load affects distractor processing, with increased inattentional blindness under high load. Given that high load can result in individuals failing to report seeing obvious objects, it is conceivable that load may also impair memory for the scene. The current study is the first to assess the effect of perceptual load on eyewitness memory. Across three experiments (two video-based and one in a driving simulator, the effect of perceptual load on eyewitness memory was assessed. The results showed that eyewitnesses were less accurate under high load, in particular for peripheral details. For example, memory for the central character in the video was not affected by load but memory for a witness who passed by the window at the edge of the scene was significantly worse under high load. High load memories were also more open to suggestion, showing increased susceptibility to leading questions. High visual perceptual load also affected recall for auditory information, illustrating a possible cross-modal perceptual load effect on memory accuracy. These results have implications for eyewitness memory researchers and forensic professionals.

  2. Load management in electrical networks. Objectives, methods, prospects

    International Nuclear Information System (INIS)

    Gabioud, D.

    2008-01-01

    This illustrated article takes up the problems related to the variation of the load in electricity networks. How to handle the peak load? Different solutions in the energy demand management are discussed. Method based on the price, method based on the reduction of the load by electric utilities. Information systems are presented which gives the consumer the needed data to participate in the local load management.

  3. Improving electrical power systems reliability through locally controlled distributed curtailable load

    Science.gov (United States)

    Dehbozorgi, Mohammad Reza

    2000-10-01

    Improvements in power system reliability have always been of interest to both power companies and customers. Since there are no sizable electrical energy storage elements in electrical power systems, the generated power should match the load demand at any given time. Failure to meet this balance may cause severe system problems, including loss of generation and system blackouts. This thesis proposes a methodology which can respond to either loss of generation or loss of load. It is based on switching of electric water heaters using power system frequency as the controlling signal. The proposed methodology encounters, and the thesis has addressed, the following associated problems. The controller must be interfaced with the existing thermostat control. When necessary to switch on loads, the water in the tank should not be overheated. Rapid switching of blocks of load, or chattering, has been considered. The contributions of the thesis are: (A) A system has been proposed which makes a significant portion of the distributed loads connected to a power system to behave in a predetermined manner to improve the power system response during disturbances. (B) The action of the proposed system is transparent to the customers. (C) The thesis proposes a simple analysis for determining the amount of such loads which might be switched and relates this amount to the size of the disturbances which can occur in the utility. (D) The proposed system acts without any formal communication links, solely using the embedded information present system-wide. (E) The methodology of the thesis proposes switching of water heater loads based on a simple, localized frequency set-point controller. The thesis has identified the consequent problem of rapid switching of distributed loads, which is referred to as chattering. (F) Two approaches have been proposed to reduce chattering to tolerable levels. (G) A frequency controller has been designed and built according to the specifications required to

  4. Short-Term Load Forecasting-Based Automatic Distribution Network Reconfiguration

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Huaiguang [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ding, Fei [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Zhang, Yingchen [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-08-23

    In a traditional dynamic network reconfiguration study, the optimal topology is determined at every scheduled time point by using the real load data measured at that time. The development of the load forecasting technique can provide an accurate prediction of the load power that will happen in a future time and provide more information about load changes. With the inclusion of load forecasting, the optimal topology can be determined based on the predicted load conditions during a longer time period instead of using a snapshot of the load at the time when the reconfiguration happens; thus, the distribution system operator can use this information to better operate the system reconfiguration and achieve optimal solutions. This paper proposes a short-term load forecasting approach to automatically reconfigure distribution systems in a dynamic and pre-event manner. Specifically, a short-term and high-resolution distribution system load forecasting approach is proposed with a forecaster based on support vector regression and parallel parameters optimization. The network reconfiguration problem is solved by using the forecasted load continuously to determine the optimal network topology with the minimum amount of loss at the future time. The simulation results validate and evaluate the proposed approach.

  5. Short-term load forecast using trend information and process reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Santos, P.J.; Pires, A.J.; Martins, J.F. [Instituto Politecnico de Setubal (Portugal). Dept. of Electrical Engineering; Martins, A.G. [University of Coimbra (Portugal). Dept. of Electrical Engineering; Mendes, R.V. [Instituto Superior Tecnico, Lisboa (Portugal). Laboratorio de Mecatronica

    2005-07-01

    The algorithms for short-term load forecast (STLF), especially within the next-hour horizon, belong to a group of methodologies that aim to render more effective the actions of planning, operating and controlling electric energy systems (EES). In the context of the progressive liberalization of the electricity sector, unbundling of the previous monopolistic structure emphasizes the need for load forecast, particularly at the network level. Methodologies such as artificial neural networks (ANN) have been widely used in next-hour load forecast. Designing an ANN requires the proper choice of input variables, avoiding overfitting and an unnecessarily complex input vector (IV). This may be achieved by trying to reduce the arbitrariness in the choice of endogenous variables. At a first stage, we have applied the mathematical techniques of process-reconstruction to the underlying stochastic process, using coding and block entropies to characterize the measure and memory range. At a second stage, the concept of consumption trend in homologous days of previous weeks has been used. The possibility to include weather-related variables in the IV has also been analysed, the option finally being to establish a model of the non-weather sensitive type. The paper uses a real-life case study. (author)

  6. Linking Health Information Systems for Effective Decision Making ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The CBHIS will consist of village registers prepared and updated every six months by volunteer community health workers (CHWs). The registers will be summarized on chalkboards and used in deliberative dialogue sessions at the community and health facility levels. The HIS will be linked to the CBHIS by including village ...

  7. Cardiorespiratory interactions during resistive load breathing.

    Science.gov (United States)

    Calabrese, P; Perrault, H; Dinh, T P; Eberhard, A; Benchetrit, G

    2000-12-01

    The addition to the respiratory system of a resistive load results in breathing pattern changes and in negative intrathoracic pressure increases. The aim of this study was to use resistive load breathing as a stimulus to the cardiorespiratory interaction and to examine the extent of the changes in heart rate variability (HRV) and respiratory sinus arrhythmia (RSA) in relation to the breathing pattern changes. HRV and RSA were studied in seven healthy subjects where four resistive loads were applied in a random order during the breath and 8-min recording made in each condition. The HRV spectral power components were computed from the R-R interval sequences, and the RSA amplitude and phase were computed from the sinusoid fitting the instantaneous heart rate within each breath. Adding resistive loads resulted in 1) increasing respiratory period, 2) unchanging heart rate, and 3) increasing HRV and changing RSA characteristics. HRV and RSA characteristics are linearly correlated to the respiratory period. These modifications appear to be linked to load-induced changes in the respiratory period in each individual, because HRV and RSA characteristics are similar at a respiratory period obtained either by loading or by imposed frequency breathing. The present results are discussed with regard to the importance of the breathing cycle duration in these cardiorespiratory interactions, suggesting that these interactions may depend on the time necessary for activation and dissipation of neurotransmitters involved in RSA.

  8. Water Quality Assessment and Total Maximum Daily Loads Information (ATTAINS)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Water Quality Assessment TMDL Tracking And Implementation System (ATTAINS) stores and tracks state water quality assessment decisions, Total Maximum Daily Loads...

  9. Perceptual load-dependent neural correlates of distractor interference inhibition.

    Directory of Open Access Journals (Sweden)

    Jiansong Xu

    2011-01-01

    Full Text Available The load theory of selective attention hypothesizes that distractor interference is suppressed after perceptual processing (i.e., in the later stage of central processing at low perceptual load of the central task, but in the early stage of perceptual processing at high perceptual load. Consistently, studies on the neural correlates of attention have found a smaller distractor-related activation in the sensory cortex at high relative to low perceptual load. However, it is not clear whether the distractor-related activation in brain regions linked to later stages of central processing (e.g., in the frontostriatal circuits is also smaller at high rather than low perceptual load, as might be predicted based on the load theory.We studied 24 healthy participants using functional magnetic resonance imaging (fMRI during a visual target identification task with two perceptual loads (low vs. high. Participants showed distractor-related increases in activation in the midbrain, striatum, occipital and medial and lateral prefrontal cortices at low load, but distractor-related decreases in activation in the midbrain ventral tegmental area and substantia nigra (VTA/SN, striatum, thalamus, and extensive sensory cortices at high load.Multiple levels of central processing involving midbrain and frontostriatal circuits participate in suppressing distractor interference at either low or high perceptual load. For suppressing distractor interference, the processing of sensory inputs in both early and late stages of central processing are enhanced at low load but inhibited at high load.

  10. Perceptual load-dependent neural correlates of distractor interference inhibition.

    Science.gov (United States)

    Xu, Jiansong; Monterosso, John; Kober, Hedy; Balodis, Iris M; Potenza, Marc N

    2011-01-18

    The load theory of selective attention hypothesizes that distractor interference is suppressed after perceptual processing (i.e., in the later stage of central processing) at low perceptual load of the central task, but in the early stage of perceptual processing at high perceptual load. Consistently, studies on the neural correlates of attention have found a smaller distractor-related activation in the sensory cortex at high relative to low perceptual load. However, it is not clear whether the distractor-related activation in brain regions linked to later stages of central processing (e.g., in the frontostriatal circuits) is also smaller at high rather than low perceptual load, as might be predicted based on the load theory. We studied 24 healthy participants using functional magnetic resonance imaging (fMRI) during a visual target identification task with two perceptual loads (low vs. high). Participants showed distractor-related increases in activation in the midbrain, striatum, occipital and medial and lateral prefrontal cortices at low load, but distractor-related decreases in activation in the midbrain ventral tegmental area and substantia nigra (VTA/SN), striatum, thalamus, and extensive sensory cortices at high load. Multiple levels of central processing involving midbrain and frontostriatal circuits participate in suppressing distractor interference at either low or high perceptual load. For suppressing distractor interference, the processing of sensory inputs in both early and late stages of central processing are enhanced at low load but inhibited at high load.

  11. Review of English Language Library and Information Science Weblogs: Analyzing the Link between Weblog Types and Their Technical /Content Structure

    Directory of Open Access Journals (Sweden)

    Tahereh Karami

    2010-09-01

    Full Text Available Weblog has become well established as one of the Web 2.0 products. Given the essential nature of their job, librarians and information professionals, can use weblog as a quick and easy mean for information and knowledge sharing. The present study reviews some 150 LIS weblogs in order to examine and analyze the link between weblog types (personal, library-owned or group operated with their content and technical structure. Webometric methods were deployed for selection of the sample. The findings indicated that there is a significant correlation between the weblog types and their update frequency. The same holds between the weblog types and their content. But no such significance was observed with respect to the weblog publishing tools. The investigators believe that the links uncovered could also hold true for Iranian LIS weblogs.

  12. Blind links, a big challenge in the linked data idea: Analysis of Persian Subject Headings

    Directory of Open Access Journals (Sweden)

    Atefeh Sharif

    2014-12-01

    Full Text Available In this survey, Linked data concept as exposing, sharing, and connecting pieces of data, information, and knowledge on the Semantic Web and some potential problems in converting Persian subject headings (PSHs Records into linked data were discussed. A data set (11233 records of PSHs was searched in three information retrieval systems including National Library of Iran (NLI online catalog, Library of Congress (LC online catalog and NOSA books. Correct links between Persian and English subject headings in the 9519 common records of two catalogs were recorded. The results indicate that the links between Persian and English subjects in 20% of records were failed. The maximum error was associated with the anonymous databases (6/7 % in NLI online catalog. It is recommended to preprocess the PSHs records before any conversion projects. It seems that, during the preprocessing, the potential errors could be identified and corrected.

  13. Perceptual Load Affects Eyewitness Accuracy & Susceptibility to Leading Questions

    OpenAIRE

    Gillian Murphy; Ciara Mary Greene

    2016-01-01

    Load Theory (Lavie, 1995; 2005) states that the level of perceptual load in a task (i.e. the amount of information involved in processing task-relevant stimuli) determines the efficiency of selective attention. There is evidence that perceptual load affects distractor processing, with increased inattentional blindness under high load. Given that high load can result in individuals failing to report seeing obvious objects, it is conceivable that load may also impair memory for the scene. The c...

  14. LabVIEW Serial Driver Software for an Electronic Load

    Science.gov (United States)

    Scullin, Vincent; Garcia, Christopher

    2003-01-01

    A LabVIEW-language computer program enables monitoring and control of a Transistor Devices, Inc., Dynaload WCL232 (or equivalent) electronic load via an RS-232 serial communication link between the electronic load and a remote personal computer. (The electronic load can operate at constant voltage, current, power consumption, or resistance.) The program generates a graphical user interface (GUI) at the computer that looks and acts like the front panel of the electronic load. Once the electronic load has been placed in remote-control mode, this program first queries the electronic load for the present values of all its operational and limit settings, and then drops into a cycle in which it reports the instantaneous voltage, current, and power values in displays that resemble those on the electronic load while monitoring the GUI images of pushbuttons for control actions by the user. By means of the pushbutton images and associated prompts, the user can perform such operations as changing limit values, the operating mode, or the set point. The benefit of this software is that it relieves the user of the need to learn one method for operating the electronic load locally and another method for operating it remotely via a personal computer.

  15. Amborella trichopoda, plasmodesmata, and the evolution of phloem loading.

    Science.gov (United States)

    Turgeon, Robert; Medville, Richard

    2011-01-01

    Phloem loading is the process by which photoassimilates synthesized in the mesophyll cells of leaves enter the sieve elements and companion cells of minor veins in preparation for long distance transport to sink organs. Three loading strategies have been described: active loading from the apoplast, passive loading via the symplast, and passive symplastic transfer followed by polymer trapping of raffinose and stachyose. We studied phloem loading in Amborella trichopoda, a premontane shrub that may be sister to all other flowering plants. The minor veins of A. trichopoda contain intermediary cells, indicative of the polymer trap mechanism, forming an arc on the abaxial side and subtending a cluster of ordinary companion cells in the interior of the veins. Intermediary cells are linked to bundle sheath cells by highly abundant plasmodesmata whereas ordinary companion cells have few plasmodesmata, characteristic of phloem that loads from the apoplast. Intermediary cells, ordinary companion cells, and sieve elements form symplastically connected complexes. Leaves provided with (14)CO(2) translocate radiolabeled sucrose, raffinose, and stachyose. Therefore, structural and physiological evidence suggests that both apoplastic and polymer trapping mechanisms of phloem loading operate in A. trichopoda. The evolution of phloem loading strategies is complex and may be difficult to resolve.

  16. New PWM method and commutation strategy for HF-link converters for fuel cells and photovoltaics

    DEFF Research Database (Denmark)

    Ljusev, Petar; Andersen, Michael Andreas E.

    2005-01-01

    This paper presents a new PWM method and commutation strategy for HF-link converters, which leads to safe commutation of the load current in the output bidirectional bridge. The proposed implementation is independent of the particular HF-link converter topology and bidirectional switch selection ...

  17. Effects of load and maintenance duration on the time course of information encoding and retrieval in working memory: from perceptual analysis to post-categorization processes.

    Directory of Open Access Journals (Sweden)

    Diego ePinal

    2014-04-01

    Full Text Available Working memory (WM involves three cognitive events: information encoding, maintenance and retrieval; these are supported by brain activity in a network of frontal, parietal and temporal regions. Manipulation of WM load and duration of the maintenance period can modulate this activity. Although such modulations have been widely studied using the ERP technique, a precise description of the time course of brain activity during encoding and retrieval is still required. Here, we used this technique and principal component analysis to assess the time course of brain activity during encoding and retrieval in a delayed match to sample task. We also investigated the effects of memory load and duration of the maintenance period on ERP activity. Brain activity was similar during information encoding and retrieval and comprised six temporal factors, which closely matched the latency and scalp distribution of some ERP components: P1, N1, P2, N2, P300 and a slow wave. Changes in memory load modulated task performance and yielded variations in frontal lobe activation. Moreover, the P300 amplitude was smaller in the high than in the low load condition during encoding and retrieval. Conversely, the slow wave amplitude was higher in the high than in the low load condition during encoding, and the same was true for the N2 amplitude during retrieval. Thus, during encoding, memory load appears to modulate the processing resources for context updating and post-categorization processes, and during retrieval it modulates resources for stimulus classification and context updating. Besides, despite the lack of differences in task performance related to duration of the maintenance period, larger N2 amplitude and stronger activation of the left temporal lobe after long than after short maintenance periods were found during information retrieval. Thus, results regarding the duration of maintenance period were complex, and future work is required to test the time-based decay

  18. Perceptual Load Affects Eyewitness Accuracy and Susceptibility to Leading Questions.

    Science.gov (United States)

    Murphy, Gillian; Greene, Ciara M

    2016-01-01

    Load Theory (Lavie, 1995, 2005) states that the level of perceptual load in a task (i.e., the amount of information involved in processing task-relevant stimuli) determines the efficiency of selective attention. There is evidence that perceptual load affects distractor processing, with increased inattentional blindness under high load. Given that high load can result in individuals failing to report seeing obvious objects, it is conceivable that load may also impair memory for the scene. The current study is the first to assess the effect of perceptual load on eyewitness memory. Across three experiments (two video-based and one in a driving simulator), the effect of perceptual load on eyewitness memory was assessed. The results showed that eyewitnesses were less accurate under high load, in particular for peripheral details. For example, memory for the central character in the video was not affected by load but memory for a witness who passed by the window at the edge of the scene was significantly worse under high load. High load memories were also more open to suggestion, showing increased susceptibility to leading questions. High visual perceptual load also affected recall for auditory information, illustrating a possible cross-modal perceptual load effect on memory accuracy. These results have implications for eyewitness memory researchers and forensic professionals.

  19. Achilles and Patellar Tendinopathy Loading Programmes

    DEFF Research Database (Denmark)

    Malliaras, Peter; Barton, Christian J; Reeves, Neil D

    2013-01-01

    . Eccentric-concentric progressing to eccentric (Silbernagel combined) and eccentric-concentric isotonic (heavy-slow resistance; HSR) loading have also been investigated. In order for clinicians to make informed decisions, they need to be aware of the loading options and comparative evidence. The mechanisms...... mechanism that was consistently associated with improved clinical outcomes in both Achilles and patellar tendon rehabilitation was improved neuromuscular performance (e.g. torque, work, endurance), and Silbernagel-combined (Achilles) HSR loading (patellar) had an equivalent or higher level of evidence than...... isolated eccentric loading. In the Achilles tendon, a majority of studies did not find an association between improved imaging (e.g. reduced anteroposterior diameter, proportion of tendons with Doppler signal) and clinical outcomes, including all high-quality studies. In contrast, HSR loading...

  20. Probability distributions of bed load particle velocities, accelerations, hop distances, and travel times informed by Jaynes's principle of maximum entropy

    Science.gov (United States)

    Furbish, David; Schmeeckle, Mark; Schumer, Rina; Fathel, Siobhan

    2016-01-01

    We describe the most likely forms of the probability distributions of bed load particle velocities, accelerations, hop distances, and travel times, in a manner that formally appeals to inferential statistics while honoring mechanical and kinematic constraints imposed by equilibrium transport conditions. The analysis is based on E. Jaynes's elaboration of the implications of the similarity between the Gibbs entropy in statistical mechanics and the Shannon entropy in information theory. By maximizing the information entropy of a distribution subject to known constraints on its moments, our choice of the form of the distribution is unbiased. The analysis suggests that particle velocities and travel times are exponentially distributed and that particle accelerations follow a Laplace distribution with zero mean. Particle hop distances, viewed alone, ought to be distributed exponentially. However, the covariance between hop distances and travel times precludes this result. Instead, the covariance structure suggests that hop distances follow a Weibull distribution. These distributions are consistent with high-resolution measurements obtained from high-speed imaging of bed load particle motions. The analysis brings us closer to choosing distributions based on our mechanical insight.

  1. Loads and loads and loads: the influence of prospective load, retrospective load, and ongoing task load in prospective memory

    Science.gov (United States)

    Meier, Beat; Zimmermann, Thomas D.

    2015-01-01

    In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load (OTL) can affect prospective memory performance. The existence of multiple target events increases prospective load (PL) and adding complexity to the to-be-remembered action increases retrospective load (RL). In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of PL on costs in the ongoing task for categorical targets (Experiment 2), but not for specific targets (Experiment 1). RL and OTL both affected remembering the retrospective component of the prospective memory task. We suggest that PL can enhance costs in the ongoing task due to additional monitoring requirements. RL and OTL seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially. PMID:26082709

  2. Loads and loads and loads: the influence of prospective load, retrospective load, and ongoing task load in prospective memory.

    Science.gov (United States)

    Meier, Beat; Zimmermann, Thomas D

    2015-01-01

    In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load (OTL) can affect prospective memory performance. The existence of multiple target events increases prospective load (PL) and adding complexity to the to-be-remembered action increases retrospective load (RL). In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of PL on costs in the ongoing task for categorical targets (Experiment 2), but not for specific targets (Experiment 1). RL and OTL both affected remembering the retrospective component of the prospective memory task. We suggest that PL can enhance costs in the ongoing task due to additional monitoring requirements. RL and OTL seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially.

  3. Compiling standardized information from clinical practice: using content analysis and ICF Linking Rules in a goal-oriented youth rehabilitation program.

    Science.gov (United States)

    Lustenberger, Nadia A; Prodinger, Birgit; Dorjbal, Delgerjargal; Rubinelli, Sara; Schmitt, Klaus; Scheel-Sailer, Anke

    2017-09-23

    To illustrate how routinely written narrative admission and discharge reports of a rehabilitation program for eight youths with chronic neurological health conditions can be transformed to the International Classification of Functioning, Disability and Health. First, a qualitative content analysis was conducted by building meaningful units with text segments assigned of the reports to the five elements of the Rehab-Cycle ® : goal; assessment; assignment; intervention; evaluation. Second, the meaningful units were then linked to the ICF using the refined ICF Linking Rules. With the first step of transformation, the emphasis of the narrative reports changed to a process oriented interdisciplinary layout, revealing three thematic blocks of goals: mobility, self-care, mental, and social functions. The linked 95 unique ICF codes could be grouped in clinically meaningful goal-centered ICF codes. Between the two independent linkers, the agreement rate was improved after complementing the rules with additional agreements. The ICF Linking Rules can be used to compile standardized health information from narrative reports if prior structured. The process requires time and expertise. To implement the ICF into common practice, the findings provide the starting point for reporting rehabilitation that builds upon existing practice and adheres to international standards. Implications for Rehabilitation This study provides evidence that routinely collected health information from rehabilitation practice can be transformed to the International Classification of Functioning, Disability and Health by using the "ICF Linking Rules", however, this requires time and expertise. The Rehab-Cycle ® , including assessments, assignments, goal setting, interventions and goal evaluation, serves as feasible framework for structuring this rehabilitation program and ensures that the complexity of local practice is appropriately reflected. The refined "ICF Linking Rules" lead to a standardized

  4. Hood River Conservation Project load analysis

    Energy Technology Data Exchange (ETDEWEB)

    Stovall, T.K.

    1987-11-01

    As a part of the Hood River Conservation Project (HRCP), 314 homes were monitored to measure electrical energy use. The total electrical load, space heating load, water heating load (in about 200 homes), wood-stove heat output (in about 100 homes), and indoor temperature were monitored. Data were collected for one full year before and one full year after these homes were retrofit with conservation measures. Local weather information was also collected on a 15-min basis. This data base was used to evaluate the load savings attributable to HRCP. Two methods of weather normalization were used and showed close agreement. The weather-normalized diversified residential load savings on the Pacific Power and Light system and Hood River area peak days were >0.5 kW/household. The average spring, summer, and fall savings were much smaller, <0.1 kW/household. The load factor for the diversified residential load decreased following the conservation retrofit actions. 11 refs., 40 figs., 13 tabs.

  5. From the genome to the phenome and back: linking genes with human brain function and structure using genetically informed neuroimaging

    DEFF Research Database (Denmark)

    Siebner, H R; Callicott, J H; Sommer, T

    2009-01-01

    In recent years, an array of brain mapping techniques has been successfully employed to link individual differences in circuit function or structure in the living human brain with individual variations in the human genome. Several proof-of-principle studies provided converging evidence that brain...... imaging can establish important links between genes and behaviour. The overarching goal is to use genetically informed brain imaging to pinpoint neurobiological mechanisms that contribute to behavioural intermediate phenotypes or disease states. This special issue on "Linking Genes to Brain Function...... in Health and Disease" provides an overview over how the "imaging genetics" approach is currently applied in the various fields of systems neuroscience to reveal the genetic underpinnings of complex behaviours and brain diseases. While the rapidly emerging field of imaging genetics holds great promise...

  6. Visuospatial information processing load and the ratio between parietal cue and target P3 amplitudes in the Attentional Network Test.

    Science.gov (United States)

    Abramov, Dimitri M; Pontes, Monique; Pontes, Adailton T; Mourao-Junior, Carlos A; Vieira, Juliana; Quero Cunha, Carla; Tamborino, Tiago; Galhanone, Paulo R; deAzevedo, Leonardo C; Lazarev, Vladimir V

    2017-04-24

    In ERP studies of cognitive processes during attentional tasks, the cue signals containing information about the target can increase the amplitude of the parietal cue P3 in relation to the 'neutral' temporal cue, and reduce the subsequent target P3 when this information is valid, i.e. corresponds to the target's attributes. The present study compared the cue-to-target P3 ratios in neutral and visuospatial cueing, in order to estimate the contribution of valid visuospatial information from the cue to target stages of the task performance, in terms of cognitive load. The P3 characteristics were also correlated with the results of individuals' performance of the visuospatial tasks, in order to estimate the relationship of the observed ERP with spatial reasoning. In 20 typically developing boys, aged 10-13 years (11.3±0.86), the intelligence quotient (I.Q.) was estimated by the Block Design and Vocabulary subtests from the WISC-III. The subjects performed the Attentional Network Test (ANT) accompanied by EEG recording. The cued two-choice task had three equiprobable cue conditions: No cue, with no information about the target; Neutral (temporal) cue, with an asterisk in the center of the visual field, predicting the target onset; and Spatial cues, with an asterisk in the upper or lower hemifield, predicting the onset and corresponding location of the target. The ERPs were estimated for the mid-frontal (Fz) and mid-parietal (Pz) scalp derivations. In the Pz, the Neutral cue P3 had a lower amplitude than the Spatial cue P3; whereas for the target ERPs, the P3 of the Neutral cue condition was larger than that of the Spatial cue condition. However, the sums of the magnitudes of the cue and target P3 were equal in the spatial and neutral cueing, probably indicating that in both cases the equivalent information processing load is included in either the cue or the target reaction, respectively. Meantime, in the Fz, the analog ERP components for both the cue and target

  7. Foot positioning instruction, initial vertical load position and lifting technique: effects on low back loading.

    Science.gov (United States)

    Kingma, Idsart; Bosch, Tim; Bruins, Louis; van Dieën, Jaap H

    2004-10-22

    This study investigated the effects of initial load height and foot placement instruction in four lifting techniques: free, stoop (bending the back), squat (bending the knees) and a modified squat technique (bending the knees and rotating them outward). A 2D dynamic linked segment model was combined with an EMG assisted trunk muscle model to quantify kinematics and low back loading in 10 subjects performing 19 different lifting movements, using 10.5 kg boxes without handles. When lifting from a 0.05 m height with the feet behind the box, squat lifting resulted in 19.9% (SD 8.7%) higher net moments (p squat and stoop lifts, as well as the interaction with lifting height, could to a large extent be explained by changes in the horizontal L5/S1 intervertebral joint position relative to the load, the upper body acceleration, and lumbar flexion. Rotating the knees outward during squat lifts resulted in moments and compression forces that were smaller than in squat lifting but larger than in stoop lifting. Shear forces were small ( < 300 N) at the L4/L5 joint and substantial (1100 - 1400 N) but unaffected by lifting technique at the L5/S1 joint. The present results show that the effects of lifting technique on low back loading depend on the task context.

  8. A Figure-of-Merit for Designing High-Performance Inductive Power Transmission Links.

    Science.gov (United States)

    Kiani, Mehdi; Ghovanloo, Maysam

    2012-11-16

    Power transfer efficiency (PTE) and power delivered to the load (PDL) are two key inductive link design parameters that relate to the power source and driver specs, power loss, transmission range, robustness against misalignment, variations in loading, and interference with other devices. Designers need to strike a delicate balance between these two because designing the link to achieve high PTE will degrade the PDL and vice versa. We are proposing a new figure-of-merit (FoM), which can help designers to find out whether a two-, three-, or four-coil link is appropriate for their particular application and guide them through an iterative design procedure to reach optimal coil geometries based on how they weigh the PTE versus PDL for that application. Three design examples at three different power levels have been presented based on the proposed FoM for implantable microelectronic devices, handheld mobile devices, and electric vehicles. The new FoM suggests that the two-coil links are suitable when the coils are strongly coupled, and a large PDL is needed. Three-coil links are the best when the coils are loosely coupled, the coupling distance varies considerably, and large PDL is necessary. Finally, four-coil links are optimal when the PTE is paramount, the coils are loosely coupled, and their relative distance and alignment are stable. Measurement results support the accuracy of the theoretical design procedure and conclusions.

  9. Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry

    Directory of Open Access Journals (Sweden)

    Kamila J. Pacholarz

    2016-06-01

    Full Text Available Antibody-drug-conjugates (ADC are a growing class of anticancer biopharmaceuticals. Conjugation of cysteine linked ADCs, requires initial reduction of mAb inter-chain disulfide bonds, as the drugs are attached via thiol chemistry. This results in the active mAb moiety being transformed from a covalently linked tetramer to non-covalently linked complexes, which hinders precise determination of drug load with LC–MS. Here, we show how the addition of the charge reducing agent triethylammonium acetate (TEAA preserves the intact mAb structure, is well suited to the study of cysteine linked conjugates and facilitates easy drug load determination by direct infusion native MS.

  10. Load beam unit replaceable inserts for dry coal extrusion pumps

    Science.gov (United States)

    Saunders, Timothy; Brady, John D.

    2012-11-13

    A track assembly for a particulate material extrusion pump according to an exemplary aspect of the present disclosure includes a link assembly with a roller bearing. An insert mounted to a load beam located such that the roller bearing contacts the insert.

  11. The Impact of Grid Unbalances on the Reliability of DC-link Capacitors in a Motor Drive

    DEFF Research Database (Denmark)

    Wang, Huai; Davari, Pooya; Kumar, Dinesh

    2017-01-01

    DC-link capacitor is one of the reliability-critical components in motor drive applications, which contributes to a considerable cost, size and failure. Its reliability performance depends on both inherent physical strength and external loading. The grid unbalances could alter the electro......-thermal stresses of key components in a motor drive. Therefore, this digest investigates the impact of grid voltage amplitude and phase unbalances on the lifetime of DC-link capacitors used in a standard three-phase motor drive. The theoretical stress models and experimental measurements of the capacitor voltages...... and ripple currents are presented. The relationship between the DC-link capacitor lifetime and the level of unbalances and loads are discussed based on a 7.5 kW motor drive system. The results serve as a guideline to size the DC-link capacitors to be robust enough at the presence of grid unbalance conditions....

  12. Fabrication of drug-loaded hydrogels with stereolithographic 3D printing.

    Science.gov (United States)

    Martinez, Pamela Robles; Goyanes, Alvaro; Basit, Abdul W; Gaisford, Simon

    2017-10-30

    3D printing (3DP) technologies have been attracting much recent interest as new methods of fabricating medicines and medical devices. Of the many types of 3DP available, stereolithographic (SLA) printing offers the unique advantage of being able to fabricate objects by cross-linking resins to form networked polymer matrices. Because water can be entrapped in these matrices, it is possible in principle to fabricate pre-wetted, drug-loaded hydrogels and devices. Here, SLA printing was used to prepare ibuprofen-loaded hydrogels of cross-linked polyethylene glycol diacrylate. Hydrogels containing up to 30% w/w water, and 10% w/w ibuprofen, were successfully printed. Dissolution profiles showed that drug release rates were dependent on water content, with higher water content hydrogels releasing drug faster. The conclusion is that SLA 3DP offers a new manufacturing route to pharmaceutical hydrogels. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Short-Term Load Forecasting Based Automatic Distribution Network Reconfiguration: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Huaiguang [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ding, Fei [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Zhang, Yingchen [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Jiang, Huaiguang [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ding, Fei [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Zhang, Yingchen [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-07-26

    In the traditional dynamic network reconfiguration study, the optimal topology is determined at every scheduled time point by using the real load data measured at that time. The development of load forecasting technique can provide accurate prediction of load power that will happen in future time and provide more information about load changes. With the inclusion of load forecasting, the optimal topology can be determined based on the predicted load conditions during the longer time period instead of using the snapshot of load at the time when the reconfiguration happens, and thus it can provide information to the distribution system operator (DSO) to better operate the system reconfiguration to achieve optimal solutions. Thus, this paper proposes a short-term load forecasting based approach for automatically reconfiguring distribution systems in a dynamic and pre-event manner. Specifically, a short-term and high-resolution distribution system load forecasting approach is proposed with support vector regression (SVR) based forecaster and parallel parameters optimization. And the network reconfiguration problem is solved by using the forecasted load continuously to determine the optimal network topology with the minimum loss at the future time. The simulation results validate and evaluate the proposed approach.

  14. Visual working memory load-related changes in neural activity and functional connectivity.

    Directory of Open Access Journals (Sweden)

    Ling Li

    Full Text Available BACKGROUND: Visual working memory (VWM helps us store visual information to prepare for subsequent behavior. The neuronal mechanisms for sustaining coherent visual information and the mechanisms for limited VWM capacity have remained uncharacterized. Although numerous studies have utilized behavioral accuracy, neural activity, and connectivity to explore the mechanism of VWM retention, little is known about the load-related changes in functional connectivity for hemi-field VWM retention. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we recorded electroencephalography (EEG from 14 normal young adults while they performed a bilateral visual field memory task. Subjects had more rapid and accurate responses to the left visual field (LVF memory condition. The difference in mean amplitude between the ipsilateral and contralateral event-related potential (ERP at parietal-occipital electrodes in retention interval period was obtained with six different memory loads. Functional connectivity between 128 scalp regions was measured by EEG phase synchronization in the theta- (4-8 Hz, alpha- (8-12 Hz, beta- (12-32 Hz, and gamma- (32-40 Hz frequency bands. The resulting matrices were converted to graphs, and mean degree, clustering coefficient and shortest path length was computed as a function of memory load. The results showed that brain networks of theta-, alpha-, beta-, and gamma- frequency bands were load-dependent and visual-field dependent. The networks of theta- and alpha- bands phase synchrony were most predominant in retention period for right visual field (RVF WM than for LVF WM. Furthermore, only for RVF memory condition, brain network density of theta-band during the retention interval were linked to the delay of behavior reaction time, and the topological property of alpha-band network was negative correlation with behavior accuracy. CONCLUSIONS/SIGNIFICANCE: We suggest that the differences in theta- and alpha- bands between LVF and RVF

  15. Visual Working Memory Load-Related Changes in Neural Activity and Functional Connectivity

    Science.gov (United States)

    Li, Ling; Zhang, Jin-Xiang; Jiang, Tao

    2011-01-01

    Background Visual working memory (VWM) helps us store visual information to prepare for subsequent behavior. The neuronal mechanisms for sustaining coherent visual information and the mechanisms for limited VWM capacity have remained uncharacterized. Although numerous studies have utilized behavioral accuracy, neural activity, and connectivity to explore the mechanism of VWM retention, little is known about the load-related changes in functional connectivity for hemi-field VWM retention. Methodology/Principal Findings In this study, we recorded electroencephalography (EEG) from 14 normal young adults while they performed a bilateral visual field memory task. Subjects had more rapid and accurate responses to the left visual field (LVF) memory condition. The difference in mean amplitude between the ipsilateral and contralateral event-related potential (ERP) at parietal-occipital electrodes in retention interval period was obtained with six different memory loads. Functional connectivity between 128 scalp regions was measured by EEG phase synchronization in the theta- (4–8 Hz), alpha- (8–12 Hz), beta- (12–32 Hz), and gamma- (32–40 Hz) frequency bands. The resulting matrices were converted to graphs, and mean degree, clustering coefficient and shortest path length was computed as a function of memory load. The results showed that brain networks of theta-, alpha-, beta-, and gamma- frequency bands were load-dependent and visual-field dependent. The networks of theta- and alpha- bands phase synchrony were most predominant in retention period for right visual field (RVF) WM than for LVF WM. Furthermore, only for RVF memory condition, brain network density of theta-band during the retention interval were linked to the delay of behavior reaction time, and the topological property of alpha-band network was negative correlation with behavior accuracy. Conclusions/Significance We suggest that the differences in theta- and alpha- bands between LVF and RVF conditions in

  16. HPV-16 viral load in oropharyngeal squamous cell carcinoma using digital PCR.

    Science.gov (United States)

    Antonsson, Annika; Knight, Lani; Panizza, Benedict J; Porceddu, Sandro V; Emmett, Sarah; Whiteman, David C

    2018-05-09

    We did not identify any strong associations between HPV-16 viral load and any of the clinical or lifestyle factors. The epidemiology of oropharyngeal SCC is changing, with an increasing proportion of HPV-positive cases seen in the last decade. It is known that a high viral load is linked to the development of cervical cancer, the relation between viral load and oropharyngeal SCC is less clear. We sought to determine HPV-16 viral load in HPV-positive oropharyngeal SCCs using highly sensitive digital PCR and to identify clinical and lifestyle factors associated with viral load. We analysed 45 HPV-16 positive oropharyngeal SCCs diagnosed between 2013 and 2015. All patients completed a lifestyle questionnaire and clinical data were extracted from medical charts. Viral load was determined using digital PCR assays for HPV-L1 and RNAseP. We found large variations in HPV-16 viral load from 1 to 930 copies per cell (median 34 copies per cell).

  17. Commercial equipment loads: End-Use Load and Consumer Assessment Program (ELCAP)

    Energy Technology Data Exchange (ETDEWEB)

    Pratt, R.G.; Williamson, M.A.; Richman, E.E.; Miller, N.E.

    1990-07-01

    The Office of Energy Resources of the Bonneville Power Administration is generally responsible for the agency's power and conservation resource planning. As associated responsibility which supports a variety of office functions is the analysis of historical trends in and determinants of energy consumption. The Office of Energy Resources' End-Use Research Section operates a comprehensive data collection program to provide pertinent information to support demand-side planning, load forecasting, and demand-side program development and delivery. Part of this on-going program is known as the End-Use Load and Consumer Assessment Program (ELCAP), an effort designed to collect electricity usage data through direct monitoring of end-use loads in buildings. This program is conducted for Bonneville by the Pacific Northwest Laboratory. This report provides detailed information on electricity consumption of miscellaneous equipment from the commercial portion of ELCAP. Miscellaneous equipment includes all commercial end-uses except heating, ventilating, air conditioning, and central lighting systems. Some examples of end-uses covered in this report are office equipment, computers, task lighting, refrigeration, and food preparation. Electricity consumption estimates, in kilowatt-hours per square food per year, are provided for each end-use by building type. The following types of buildings are covered: office, retail, restaurant, grocery, warehouse, school, university, and hotel/motel. 6 refs., 35 figs., 12 tabs.

  18. Loading functions for assessment of water pollution from nonpoint sources

    International Nuclear Information System (INIS)

    McElroy, A.D.; Chiu, S.Y.; Nebgen, J.W.; Aleti, A.; Bennett, F.W.

    1976-05-01

    Methods for evaluating the quantity of water pollutants generated from nonpoint sources including agriculture, silviculture, construction, mining, runoff from urban areas and rural roads, and terrestrial disposal are developed and compiled for use in water quality planning. The loading functions, plus in some instances emission values, permit calculation of nonpoint source pollutants from available data and information. Natural background was considered to be a source and loading functions were presented to estimate natural or background loads of pollutants. Loading functions/values are presented for average conditions, i.e., annual average loads expressed as metric tons/hectare/year (tons/acre/year). Procedures for estimating seasonal or 30-day maximum and minimum loads are also presented. In addition, a wide variety of required data inputs to loading functions, and delineation of sources of additional information are included in the report. The report also presents an evaluation of limitations and constraints of various methodologies which will enable the user to employ the functions realistically

  19. Load frequency control of an asynchronous restructured power system

    African Journals Online (AJOL)

    This paper presents the analysis of load frequency control (LFC) of a two-area restructured power system interconnected via parallel ac/dc transmission links. Simulation results show that the limitations of PI controller can be overcome by including Fuzzy logic concept and thereby the dynamic performance can be improved ...

  20. Linking disease associations with regulatory information in the human genome

    KAUST Repository

    Schaub, M. A.; Boyle, A. P.; Kundaje, A.; Batzoglou, S.; Snyder, M.

    2012-01-01

    Genome-wide association studies have been successful in identifying single nucleotide polymorphisms (SNPs) associated with a large number of phenotypes. However, an associated SNP is likely part of a larger region of linkage disequilibrium. This makes it difficult to precisely identify the SNPs that have a biological link with the phenotype. We have systematically investigated the association of multiple types of ENCODE data with disease-associated SNPs and show that there is significant enrichment for functional SNPs among the currently identified associations. This enrichment is strongest when integrating multiple sources of functional information and when highest confidence disease-associated SNPs are used. We propose an approach that integrates multiple types of functional data generated by the ENCODE Consortium to help identify "functional SNPs" that may be associated with the disease phenotype. Our approach generates putative functional annotations for up to 80% of all previously reported associations. We show that for most associations, the functional SNP most strongly supported by experimental evidence is a SNP in linkage disequilibrium with the reported association rather than the reported SNP itself. Our results show that the experimental data sets generated by the ENCODE Consortium can be successfully used to suggest functional hypotheses for variants associated with diseases and other phenotypes.

  1. Linking disease associations with regulatory information in the human genome

    KAUST Repository

    Schaub, M. A.

    2012-09-01

    Genome-wide association studies have been successful in identifying single nucleotide polymorphisms (SNPs) associated with a large number of phenotypes. However, an associated SNP is likely part of a larger region of linkage disequilibrium. This makes it difficult to precisely identify the SNPs that have a biological link with the phenotype. We have systematically investigated the association of multiple types of ENCODE data with disease-associated SNPs and show that there is significant enrichment for functional SNPs among the currently identified associations. This enrichment is strongest when integrating multiple sources of functional information and when highest confidence disease-associated SNPs are used. We propose an approach that integrates multiple types of functional data generated by the ENCODE Consortium to help identify "functional SNPs" that may be associated with the disease phenotype. Our approach generates putative functional annotations for up to 80% of all previously reported associations. We show that for most associations, the functional SNP most strongly supported by experimental evidence is a SNP in linkage disequilibrium with the reported association rather than the reported SNP itself. Our results show that the experimental data sets generated by the ENCODE Consortium can be successfully used to suggest functional hypotheses for variants associated with diseases and other phenotypes.

  2. Information technology and innovative drainage management practices for selenium load reduction from irrigated agriculture to provide stakeholder assurances and meet contaminant mass loading policy objectives

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, N.W.T.

    2009-10-15

    Many perceive the implementation of environmental regulatory policy, especially concerning non-point source pollution from irrigated agriculture, as being less efficient in the United States than in many other countries. This is partly a result of the stakeholder involvement process but is also a reflection of the inability to make effective use of Environmental Decision Support Systems (EDSS) to facilitate technical information exchange with stakeholders and to provide a forum for innovative ideas for controlling non-point source pollutant loading. This paper describes one of the success stories where a standardized Environmental Protection Agency (EPA) methodology was modified to better suit regulation of a trace element in agricultural subsurface drainage and information technology was developed to help guide stakeholders, provide assurances to the public and encourage innovation while improving compliance with State water quality objectives. The geographic focus of the paper is the western San Joaquin Valley where, in 1985, evapoconcentration of selenium in agricultural subsurface drainage water, diverted into large ponds within a federal wildlife refuge, caused teratogenecity in waterfowl embryos and in other sensitive wildlife species. The fallout from this environmental disaster was a concerted attempt by State and Federal water agencies to regulate non-point source loads of the trace element selenium. The complexity of selenium hydrogeochemistry, the difficulty and expense of selenium concentration monitoring and political discord between agricultural and environmental interests created challenges to the regulation process. Innovative policy and institutional constructs, supported by environmental monitoring and the web-based data management and dissemination systems, provided essential decision support, created opportunities for adaptive management and ultimately contributed to project success. The paper provides a retrospective on the contentious planning

  3. Running accuracy analysis of a 3-RRR parallel kinematic machine considering the deformations of the links

    Science.gov (United States)

    Wang, Liping; Jiang, Yao; Li, Tiemin

    2014-09-01

    Parallel kinematic machines have drawn considerable attention and have been widely used in some special fields. However, high precision is still one of the challenges when they are used for advanced machine tools. One of the main reasons is that the kinematic chains of parallel kinematic machines are composed of elongated links that can easily suffer deformations, especially at high speeds and under heavy loads. A 3-RRR parallel kinematic machine is taken as a study object for investigating its accuracy with the consideration of the deformations of its links during the motion process. Based on the dynamic model constructed by the Newton-Euler method, all the inertia loads and constraint forces of the links are computed and their deformations are derived. Then the kinematic errors of the machine are derived with the consideration of the deformations of the links. Through further derivation, the accuracy of the machine is given in a simple explicit expression, which will be helpful to increase the calculating speed. The accuracy of this machine when following a selected circle path is simulated. The influences of magnitude of the maximum acceleration and external loads on the running accuracy of the machine are investigated. The results show that the external loads will deteriorate the accuracy of the machine tremendously when their direction coincides with the direction of the worst stiffness of the machine. The proposed method provides a solution for predicting the running accuracy of the parallel kinematic machines and can also be used in their design optimization as well as selection of suitable running parameters.

  4. Controllable Load Management Approaches in Smart Grids

    Directory of Open Access Journals (Sweden)

    Jingshuang Shen

    2015-10-01

    Full Text Available With rapid smart grid technology development, the customer can actively participate in demand-side management (DSM with the mutual information communication between the distributor operation company and the smart devices in real-time. Controllable load management not only has the advantage of peak shaving, load balance, frequency regulation, and voltage stability, but is also effective at providing fast balancing services to the renewable energy grid in the distributed power system. The load management faces an enormous challenge as the customer has a large number of both small residential loads and dispersed renewable sources. In this paper, various controllable load management approaches are discussed. The traditional controllable load approaches such as the end users’ controllable appliances, storage battery, Vehicle-to-Grid (V2G, and heat storage are reviewed. The “broad controllable loads” management, such as the microgrid, Virtual Power Plant (VPP, and the load aggregator are also presented. Furthermore, the load characteristics, control strategies, and control effectiveness are analyzed.

  5. LinkMind: link optimization in swarming mobile sensor networks.

    Science.gov (United States)

    Ngo, Trung Dung

    2011-01-01

    A swarming mobile sensor network is comprised of a swarm of wirelessly connected mobile robots equipped with various sensors. Such a network can be applied in an uncertain environment for services such as cooperative navigation and exploration, object identification and information gathering. One of the most advantageous properties of the swarming wireless sensor network is that mobile nodes can work cooperatively to organize an ad-hoc network and optimize the network link capacity to maximize the transmission of gathered data from a source to a target. This paper describes a new method of link optimization of swarming mobile sensor networks. The new method is based on combination of the artificial potential force guaranteeing connectivities of the mobile sensor nodes and the max-flow min-cut theorem of graph theory ensuring optimization of the network link capacity. The developed algorithm is demonstrated and evaluated in simulation.

  6. LinkMind: Link Optimization in Swarming Mobile Sensor Networks

    Directory of Open Access Journals (Sweden)

    Trung Dung Ngo

    2011-08-01

    Full Text Available A swarming mobile sensor network is comprised of a swarm of wirelessly connected mobile robots equipped with various sensors. Such a network can be applied in an uncertain environment for services such as cooperative navigation and exploration, object identification and information gathering. One of the most advantageous properties of the swarming wireless sensor network is that mobile nodes can work cooperatively to organize an ad-hoc network and optimize the network link capacity to maximize the transmission of gathered data from a source to a target. This paper describes a new method of link optimization of swarming mobile sensor networks. The new method is based on combination of the artificial potential force guaranteeing connectivities of the mobile sensor nodes and the max-flow min-cut theorem of graph theory ensuring optimization of the network link capacity. The developed algorithm is demonstrated and evaluated in simulation.

  7. Medium-term load forecasting and wholesale transaction profitability

    International Nuclear Information System (INIS)

    Selker, F.K.; Wroblewski, W.R.

    1996-01-01

    The volume of wholesale transactions quoted at firm prices is increasing. The cost, and thus profitability, of serving these contracts strongly depends upon native load during the time of delivery. However, transactions extend beyond load forecasts based on weather information, and long-term resource planning forecasts of load peaks and energy provide inadequate detail. To address this need, Decision Focus Inc. (DFI) and Commonwealth Edison (ComEd) developed a probabilistic, medium-term load forecasting capability. In this paper the authors use a hypothetical utility to explore the impact of uncertain medium-term loads on transaction profitability

  8. Evaluative pressure overcomes perceptual load effects.

    Science.gov (United States)

    Normand, Alice; Autin, Frédérique; Croizet, Jean-Claude

    2015-06-01

    Perceptual load has been found to be a powerful bottom-up determinant of distractibility, with high perceptual load preventing distraction by any irrelevant information. However, when under evaluative pressure, individuals exert top-down attentional control by giving greater weight to task-relevant features, making them more distractible from task-relevant distractors. One study tested whether the top-down modulation of attention under evaluative pressure overcomes the beneficial bottom-up effect of high perceptual load on distraction. Using a response-competition task, we replicated previous findings that high levels of perceptual load suppress task-relevant distractor response interference, but only for participants in a control condition. Participants under evaluative pressure (i.e., who believed their intelligence was assessed) showed interference from task-relevant distractor at all levels of perceptual load. This research challenges the assumptions of the perceptual load theory and sheds light on a neglected determinant of distractibility: the self-relevance of the performance situation in which attentional control is solicited.

  9. Perceptual Load Affects Eyewitness Accuracy and Susceptibility to Leading Questions

    OpenAIRE

    Murphy, Gillian; Greene, Ciara M.

    2016-01-01

    Load Theory (Lavie, 1995, 2005) states that the level of perceptual load in a task (i.e., the amount of information involved in processing task-relevant stimuli) determines the efficiency of selective attention. There is evidence that perceptual load affects distractor processing, with increased inattentional blindness under high load. Given that high load can result in individuals failing to report seeing obvious objects, it is conceivable that load may also impair memory for the scene. The ...

  10. A data-driven wavelet-based approach for generating jumping loads

    Science.gov (United States)

    Chen, Jun; Li, Guo; Racic, Vitomir

    2018-06-01

    This paper suggests an approach to generate human jumping loads using wavelet transform and a database of individual jumping force records. A total of 970 individual jumping force records of various frequencies were first collected by three experiments from 147 test subjects. For each record, every jumping pulse was extracted and decomposed into seven levels by wavelet transform. All the decomposition coefficients were stored in an information database. Probability distributions of jumping cycle period, contact ratio and energy of the jumping pulse were statistically analyzed. Inspired by the theory of DNA recombination, an approach was developed by interchanging the wavelet coefficients between different jumping pulses. To generate a jumping force time history with N pulses, wavelet coefficients were first selected randomly from the database at each level. They were then used to reconstruct N pulses by the inverse wavelet transform. Jumping cycle periods and contract ratios were then generated randomly based on their probabilistic functions. These parameters were assigned to each of the N pulses which were in turn scaled by the amplitude factors βi to account for energy relationship between successive pulses. The final jumping force time history was obtained by linking all the N cycles end to end. This simulation approach can preserve the non-stationary features of the jumping load force in time-frequency domain. Application indicates that this approach can be used to generate jumping force time history due to single people jumping and also can be extended further to stochastic jumping loads due to groups and crowds.

  11. The SAIL databank: linking multiple health and social care datasets.

    Science.gov (United States)

    Lyons, Ronan A; Jones, Kerina H; John, Gareth; Brooks, Caroline J; Verplancke, Jean-Philippe; Ford, David V; Brown, Ginevra; Leake, Ken

    2009-01-16

    Vast amounts of data are collected about patients and service users in the course of health and social care service delivery. Electronic data systems for patient records have the potential to revolutionise service delivery and research. But in order to achieve this, it is essential that the ability to link the data at the individual record level be retained whilst adhering to the principles of information governance. The SAIL (Secure Anonymised Information Linkage) databank has been established using disparate datasets, and over 500 million records from multiple health and social care service providers have been loaded to date, with further growth in progress. Having established the infrastructure of the databank, the aim of this work was to develop and implement an accurate matching process to enable the assignment of a unique Anonymous Linking Field (ALF) to person-based records to make the databank ready for record-linkage research studies. An SQL-based matching algorithm (MACRAL, Matching Algorithm for Consistent Results in Anonymised Linkage) was developed for this purpose. Firstly the suitability of using a valid NHS number as the basis of a unique identifier was assessed using MACRAL. Secondly, MACRAL was applied in turn to match primary care, secondary care and social services datasets to the NHS Administrative Register (NHSAR), to assess the efficacy of this process, and the optimum matching technique. The validation of using the NHS number yielded specificity values > 99.8% and sensitivity values > 94.6% using probabilistic record linkage (PRL) at the 50% threshold, and error rates were SAIL databank represents a research-ready platform for record-linkage studies.

  12. Link Anchors in Images: Is there Truth?

    NARCIS (Netherlands)

    Aly, Robin; McGuinness, Kevin; Kleppe, Martijn; Ordelman, Roeland J.F.; O'Connor, Noel; de Jong, Franciska M.G.

    2012-01-01

    While automatic linking in text collections is well understood, little is known about links in images. In this work, we investigate two aspects of anchors, the origin of a link, in images: 1) the requirements of users for such anchors, e.g. the things users would like more information on, and 2)

  13. Students' Scientific Epistemic Beliefs, Online Evaluative Standards, and Online Searching Strategies for Science Information: The Moderating Role of Cognitive Load Experience

    Science.gov (United States)

    Hsieh, Ya-Hui; Tsai, Chin-Chung

    2014-01-01

    The purpose of this study is to examine the moderating role of cognitive load experience between students' scientific epistemic beliefs and information commitments, which refer to online evaluative standards and online searching strategies. A total of 344 science-related major students participated in this study. Three questionnaires were…

  14. Synthesis, characterization, release kinetics and toxicity profile of drug-loaded starch nanoparticles.

    Science.gov (United States)

    El-Naggar, Mehrez E; El-Rafie, M H; El-sheikh, M A; El-Feky, Gina S; Hebeish, A

    2015-11-01

    The current research work focuses on the medical application of the cost-effective cross-linked starch nanoparticles, for the transdermal delivery using Diclofenac sodium (DS) as a model drug. The prepared DS-cross-linked starch nanoparticles were synthesized using nanoprecipitation technique at different concentrations of sodium tripolyphosphate (STPP) in the presence of Tween 80 as a surfactant. The resultant cross-linked starch nanoparticles loaded with DS were characterized using world-class facilities such as TEM, DLS, FT-IR, XRD, and DSc. The efficiency of DS loading was also evaluated via entrapment efficiency as well as in vitro release and histopathological study on rat skin. The optimum nanoparticles formulation selected by the JMP(®) software was the formula that composed of 5% maize starch, 57.7mg DS and 0.5% STPP and 0.4% Tween 80, with particle diameter of about 21.04nm, polydispersity index of 0.2 and zeta potential of -35.3mV. It is also worth noting that this selected formula shows an average entrapment efficiency of 95.01 and sustained DS release up to 6h. The histophathological studies using the best formula on rat skin advocate the use of designed transdermal DS loaded cross-linked starch nanoparticles as it is safe and non-irritant to rat skin. The overall results indicate that, the starch nanoparticles could be considered as a good carrier for DS drug regarding the enhancement in its controlled release and successful permeation, thus, offering a promising nanoparticulate system for the transdermal delivery non-steroidal anti-inflammatory drug (NSAID). Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Fifty years of genetic load

    International Nuclear Information System (INIS)

    Wallace, B.

    1991-01-01

    This book discusses the radiation effects on Drosophila. It was originally thought that irradiating Drosophila would decrease the average fitness of the population, thereby leading to information about the detrimental effects of mutations. Surprisingly, the fitness of the irradiated population turned out to be higher than that of the control population. The original motivation for the experiment was as a test of genetic load theory. The average fitness of a population is depressed by deleterious alleles held in the population by the balance between mutation and natural selection. The depression is called the genetic load of the population. The load dose not depend on the magnitude of the deleterious effect of alleles, but only on the mutation rate

  16. Beyond information retrieval: information discovery and multimedia information retrieval

    OpenAIRE

    Roberto Raieli

    2017-01-01

    The paper compares the current methodologies for search and discovery of information and information resources: terminological search and term-based language, own of information retrieval (IR); semantic search and information discovery, being developed mainly through the language of linked data; semiotic search and content-based language, experienced by multimedia information retrieval (MIR).MIR semiotic methodology is, then, detailed.

  17. Full State Estimation for Helicopter Slung Load System

    DEFF Research Database (Denmark)

    Bisgaard, Morten; la Cour-Harbo, Anders; Bendtsen, Jan Dimon

    This paper presents the design of a state estimator system for a generic helicopter based slung load system. The estimator is designed to deliver full rigid body state information for both helicopter and load and is based on the unscented Kalman filter. Two different approaches are investigated......: One based on a parameter free kinematic model and one based on a full aerodynamic helicopter and slung load model. The kinematic model approach uses acceleration and rate information from two Inertial Measurement Units, one on the helicopter and one on the load, to drive a simple kinematic model....... A simple and effective virtual sensor method is developed to maintain the constraints imposed by the wires in the system. The full model based approach uses a complex aerodynamical model to describe the helicopter together with a generic rigid body model. This rigid body model is based on a redundant...

  18. Full State Estimation for Helicopter Slung Load System

    DEFF Research Database (Denmark)

    Bisgaard, Morten; la Cour-Harbo, Anders; Bendtsen, Jan Dimon

    2007-01-01

    This paper presents the design of a state estimator system for a generic helicopter based slung load system. The estimator is designed to deliver full rigid body state information for both helicopter and load and is based on the unscented Kalman filter. Two different approaches are investigated......: One based on a parameter free kinematic model and one based on a full aerodynamic helicopter and slung load model. The kinematic model approach uses acceleration and rate information from two Inertial Measurement Units, one on the helicopter and one on the load, to drive a simple kinematic model....... A simple and effective virtual sensor method is developed to maintain the constraints imposed by the wires in the system. The full model based approach uses a complex aerodynamical model to describe the helicopter together with a generic rigid body model. This rigid body model is based on a redundant...

  19. Cognitive load theory: implications of cognitive load theory on the design of learning

    NARCIS (Netherlands)

    Kirschner, P.A.

    2002-01-01

    Cognitive load theory (CLT) can provide guidelines to assist in the presentation of information in a manner that encourages learner activities that optimise intellectual performance. It is based on a cognitive architecture that consists of a limited working memory, with partly independent

  20. A comprehensive comparison of network similarities for link prediction and spurious link elimination

    Science.gov (United States)

    Zhang, Peng; Qiu, Dan; Zeng, An; Xiao, Jinghua

    2018-06-01

    Identifying missing interactions in complex networks, known as link prediction, is realized by estimating the likelihood of the existence of a link between two nodes according to the observed links and nodes' attributes. Similar approaches have also been employed to identify and remove spurious links in networks which is crucial for improving the reliability of network data. In network science, the likelihood for two nodes having a connection strongly depends on their structural similarity. The key to address these two problems thus becomes how to objectively measure the similarity between nodes in networks. In the literature, numerous network similarity metrics have been proposed and their accuracy has been discussed independently in previous works. In this paper, we systematically compare the accuracy of 18 similarity metrics in both link prediction and spurious link elimination when the observed networks are very sparse or consist of inaccurate linking information. Interestingly, some methods have high prediction accuracy, they tend to perform low accuracy in identification spurious interaction. We further find that methods can be classified into several cluster according to their behaviors. This work is useful for guiding future use of these similarity metrics for different purposes.

  1. Performance Analysis of Savonius Rotor Based Hydropower Generation Scheme with Electronic Load Controller

    Directory of Open Access Journals (Sweden)

    Rajen Pudur

    2016-01-01

    Full Text Available This paper describes the performance of electronic load controller (ELC of asynchronous generator (AG coupled to an uncontrolled Savonius turbine and variable water velocity. An AC-DC-AC converter with a dc link capacitor is employed to maintain the required frequency. The ELC which is feeding a resistive dump load is connected in parallel with the generating system and the power consumption is varied through the duty cycle of the chopper. Gate triggering of ELC is accomplished through sinusoidal pulse width modulation (SPWM by sensing the load current. A MATLAB/Simulink model of Savonius rotor, asynchronous generator, ELC, and three-phase load is presented. The proposed scheme is tested under various load conditions under varying water velocities and the performances are observed to be satisfactory.

  2. Meta-path based heterogeneous combat network link prediction

    Science.gov (United States)

    Li, Jichao; Ge, Bingfeng; Yang, Kewei; Chen, Yingwu; Tan, Yuejin

    2017-09-01

    The combat system-of-systems in high-tech informative warfare, composed of many interconnected combat systems of different types, can be regarded as a type of complex heterogeneous network. Link prediction for heterogeneous combat networks (HCNs) is of significant military value, as it facilitates reconfiguring combat networks to represent the complex real-world network topology as appropriate with observed information. This paper proposes a novel integrated methodology framework called HCNMP (HCN link prediction based on meta-path) to predict multiple types of links simultaneously for an HCN. More specifically, the concept of HCN meta-paths is introduced, through which the HCNMP can accumulate information by extracting different features of HCN links for all the six defined types. Next, an HCN link prediction model, based on meta-path features, is built to predict all types of links of the HCN simultaneously. Then, the solution algorithm for the HCN link prediction model is proposed, in which the prediction results are obtained by iteratively updating with the newly predicted results until the results in the HCN converge or reach a certain maximum iteration number. Finally, numerical experiments on the dataset of a real HCN are conducted to demonstrate the feasibility and effectiveness of the proposed HCNMP, in comparison with 30 baseline methods. The results show that the performance of the HCNMP is superior to those of the baseline methods.

  3. Optimal RTP Based Power Scheduling for Residential Load in Smart Grid

    Science.gov (United States)

    Joshi, Hemant I.; Pandya, Vivek J.

    2015-12-01

    To match supply and demand, shifting of load from peak period to off-peak period is one of the effective solutions. Presently flat rate tariff is used in major part of the world. This type of tariff doesn't give incentives to the customers if they use electrical energy during off-peak period. If real time pricing (RTP) tariff is used, consumers can be encouraged to use energy during off-peak period. Due to advancement in information and communication technology, two-way communications is possible between consumers and utility. To implement this technique in smart grid, home energy controller (HEC), smart meters, home area network (HAN) and communication link between consumers and utility are required. HEC interacts automatically by running an algorithm to find optimal energy consumption schedule for each consumer. However, all the consumers are not allowed to shift their load simultaneously during off-peak period to avoid rebound peak condition. Peak to average ratio (PAR) is considered while carrying out minimization problem. Linear programming problem (LPP) method is used for minimization. The simulation results of this work show the effectiveness of the minimization method adopted. The hardware work is in progress and the program based on the method described here will be made to solve real problem.

  4. Development of a prototype continuity of care record with context-specific links to meet the information needs of case managers for persons living with HIV.

    Science.gov (United States)

    Schnall, Rebecca; Cimino, James J; Bakken, Suzanne

    2012-08-01

    (1) To develop a prototype Continuity of Care Record (CCR) with context-specific links to electronic HIV information resources; and (2) to assess case managers' perceptions regarding the usability of the prototype. We integrated context-specific links to HIV case management information resources into a prototype CCR using the Infobutton Manager and Librarian Infobutton Tailoring Environment (LITE). Case managers (N=9) completed a think-aloud protocol and the Computer System Usability Questionnaire (CSUQ) to evaluate the usability of the prototype. Verbalizations from the think-aloud protocol were summarized using thematic analysis. CSUQ data were analyzed with descriptive statistics. Although participants expressed positive comments regarding the usability of the prototype, the think-aloud protocol also identified the need for improvement in resource labels and for additional resources. On a scale ranging from 1 (strongly agree) to 7 (strongly disagree), the average CSUQ overall satisfaction was 2.25 indicating that users (n=9) were generally satisfied with the system. Mean CSUQ factor scores were: System Usefulness (M=2.13), Information Quality (M=2.46), and Interface Quality (M=2.26). Our novel application of the Infobutton Manager and LITE in the context of case management for persons living with HIV in community-based settings resulted in a prototype CCR with infobuttons that met the majority of case managers' information needs and received relatively positive usability ratings. Findings from this study inform future integration of context-specific links into CCRs and electronic health records and support their use for meeting end-users information needs. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  5. Measuring Load on Working Memory: The Use of Heart Rate as a Means of Measuring Chemistry Students' Cognitive Load

    Science.gov (United States)

    Cranford, Kristen N.; Tiettmeyer, Jessica M.; Chuprinko, Bryan C.; Jordan, Sophia; Grove, Nathaniel P.

    2014-01-01

    Information processing provides a powerful model for understanding how learning occurs and highlights the important role that cognitive load plays in this process. In instances in which the cognitive load of a problem exceeds the available working memory, learning can be seriously hindered. Previously reported methods for measuring cognitive load…

  6. An assessment of landscape characteristics affecting estuarine nitrogen loading in an urban watershed.

    Science.gov (United States)

    Yang, Xiaojun

    2012-02-01

    Exploring the quantitative association between landscape characteristics and the ecological conditions of receiving waters has recently become an emerging area for eco-environmental research. While the landscape-water relationship research has largely targeted on inland aquatic systems, there has been an increasing need to develop methods and techniques that can better work with coastal and estuarine ecosystems. In this paper, we present a geospatial approach to examine the quantitative relationship between landscape characteristics and estuarine nitrogen loading in an urban watershed. The case study site is in the Pensacola estuarine drainage area, home of the city of Pensacola, Florida, USA, where vigorous urban sprawling has prompted growing concerns on the estuarine ecological health. Central to this research is a remote sensor image that has been used to extract land use/cover information and derive landscape metrics. Several significant landscape metrics are selected and spatially linked with the nitrogen loading data for the Pensacola bay area. Landscape metrics and nitrogen loading are summarized by equal overland flow-length rings, and their association is examined by using multivariate statistical analysis. And a stepwise model-building protocol is used for regression designs to help identify significant variables that can explain much of the variance in the nitrogen loading dataset. It is found that using landscape composition or spatial configuration alone can explain most of the nitrogen loading variability. Of all the regression models using metrics derived from a single land use/cover class as the independent variables, the one from the low density urban gives the highest adjusted R-square score, suggesting the impact of the watershed-wide urban sprawl upon this sensitive estuarine ecosystem. Measures towards the reduction of non-point source pollution from urban development are necessary in the area to protect the Pensacola bay ecosystem and its

  7. Attentional capture under high perceptual load.

    Science.gov (United States)

    Cosman, Joshua D; Vecera, Shaun P

    2010-12-01

    Attentional capture by abrupt onsets can be modulated by several factors, including the complexity, or perceptual load, of a scene. We have recently demonstrated that observers are less likely to be captured by abruptly appearing, task-irrelevant stimuli when they perform a search that is high, as opposed to low, in perceptual load (Cosman & Vecera, 2009), consistent with perceptual load theory. However, recent results indicate that onset frequency can influence stimulus-driven capture, with infrequent onsets capturing attention more often than did frequent onsets. Importantly, in our previous task, an abrupt onset was present on every trial, and consequently, attentional capture might have been affected by both onset frequency and perceptual load. In the present experiment, we examined whether onset frequency influences attentional capture under conditions of high perceptual load. When onsets were presented frequently, we replicated our earlier results; attentional capture by onsets was modulated under conditions of high perceptual load. Importantly, however, when onsets were presented infrequently, we observed robust capture effects. These results conflict with a strong form of load theory and, instead, suggest that exposure to the elements of a task (e.g., abrupt onsets) combines with high perceptual load to modulate attentional capture by task-irrelevant information.

  8. Comparison of coupled and uncoupled load simulations on a jacket support structure

    DEFF Research Database (Denmark)

    Haselbach, Philipp Ulrich; Natarajan, Anand; Jiwinangun, Randi Gusto

    2013-01-01

    In this article, a comparison of the moments and forces at the joints of a jacket structure is made between fully coupled aerohydroelastic simulations in HAWC2 and uncoupled load predictions in the finite element software Abaqus. The jacket sub structure is modelled in moderate deep waters of 50m...... structure similar to the Upwind reference jacket is developed in the Abaqus environment, to which is added the transition piece and tower. The aeroelastic loads determined in normal operating conditions of the turbine is integrated and centralized as nodal forces and moments acting at the tower top...... in Abaqus. The fully coupled simulation is implemented and performed in HAWC2. In the uncoupled case, the loads (wave loads and tower base loads) are analysed by an implicit structural Finite Element Analysis (Abaqus 6.11-1). A subroutine is used as a preprocessor generating a beam element model and linking...

  9. Analysis of Mesh Distribution Systems Considering Load Models and Load Growth Impact with Loops on System Performance

    Science.gov (United States)

    Kumar Sharma, A.; Murty, V. V. S. N.

    2014-12-01

    The distribution system is the final link between bulk power system and consumer end. A distinctive load flow solution method is used for analysis of the load flow of radial and weakly meshed network based on Kirchhoff's Current Law (KCL) and KVL. This method has excellent convergence characteristics for both radial as well as weakly meshed structure and is based on bus injection to branch current and branch-current to bus-voltage matrix. The main contribution of the paper is: (i) an analysis has been carried out for a weekly mesh network considering number of loops addition and its impact on the losses, kW and kVAr requirements from a system, and voltage profile, (ii) different load models, realistic ZIP load model and load growth impact on losses, voltage profile, kVA and kVAr requirements, (iii) impact of addition of loops on losses, voltage profile, kVA and kVAr requirements from substation, and (iv) comparison of system performance with radial distribution system. Voltage stability is a major concern in planning and operation of power systems. This paper also includes identifying the closeness critical bus which is the most sensitive to the voltage collapse in radial distribution networks. Node having minimum value of voltage stability index is the most sensitive node. Voltage stability index values are computed for meshed network with number of loops added in the system. The results have been obtained for IEEE 33 and 69 bus test system. The results have also been obtained for radial distribution system for comparison.

  10. Development of Alarm System link Drawing for Operation Support for APR1400 Digital Main Control Room

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki-Hwan [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    Digitalized MMI(Man-Machine Interface) including Digital Main Control Room(MCR) and digital I and C system was being applied for SKN 3 and 4 Nuclear Power Plant(NPP) and subsequent APR1400 NPP type. But, operators can not easily find instrument for alarm immediately. Therefore, Alarm system is required to easily find instrument for Alarm. For this implementation, we will plan system design considering design feature without affecting network load and CPU load. We have developed Alarm system link drawing for digital MCR. Operators of the digitalized MCR navigates from their consoles to the drawings related to the plant alarms and their instruments or the operation status. Such method gives cognitive load to the operators having to travel to different locations in finding the related information. Screen Sharing System, which is the fundamental technique for Drawing Interconnection Alarm System is close to completion, and it should be functionally tested and verified by the human factor engineering. For the actual application to the operating plants, the drawings to be interconnected to the alarms and the opinions from the operators/maintenance departments for designating alarm number should be surveyed, Also, another function that allows the access to the alarm related drawings not only from the MCR but also from the other offices.

  11. Development of Alarm System link Drawing for Operation Support for APR1400 Digital Main Control Room

    International Nuclear Information System (INIS)

    Kim, Ki-Hwan

    2016-01-01

    Digitalized MMI(Man-Machine Interface) including Digital Main Control Room(MCR) and digital I and C system was being applied for SKN 3 and 4 Nuclear Power Plant(NPP) and subsequent APR1400 NPP type. But, operators can not easily find instrument for alarm immediately. Therefore, Alarm system is required to easily find instrument for Alarm. For this implementation, we will plan system design considering design feature without affecting network load and CPU load. We have developed Alarm system link drawing for digital MCR. Operators of the digitalized MCR navigates from their consoles to the drawings related to the plant alarms and their instruments or the operation status. Such method gives cognitive load to the operators having to travel to different locations in finding the related information. Screen Sharing System, which is the fundamental technique for Drawing Interconnection Alarm System is close to completion, and it should be functionally tested and verified by the human factor engineering. For the actual application to the operating plants, the drawings to be interconnected to the alarms and the opinions from the operators/maintenance departments for designating alarm number should be surveyed, Also, another function that allows the access to the alarm related drawings not only from the MCR but also from the other offices

  12. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... al. “Methamphetamine increases brain viral load and activates natural killer cells in simian immunodeficiency virus-infected monkeys. ... clinical trials, and other research information for health care providers, researchers, people affected by HIV/AIDS, and ...

  13. Configuration management and load monitoring procedures for nuclear plant structures

    International Nuclear Information System (INIS)

    Chu, S.L.; Skaczylo, A.T.

    1990-01-01

    This paper describes a computer-aided engineering tool called the Load Monitoring System (LMS) that was proven effective for monitoring floor framing, loads, and structural integrity. The system links structural analysis, design investigation, and reporting and automated drafting programs with a Data Base Management System (DBMS). It provides design engineers with a powerful tool for quickly incorporating, tracking, and assessing load revisions and determining effects on steel floor framing members and connections, thereby helping to reduce design man-hours, minimize the impact of structural modifications, and maintain and document the design baseline. The major benefit to utilities are the reduction in engineering costs, assistance with plant configuration management, and assurance of structural safety throughout the operating life of a nuclear plant and at evaluation for license renewal. (orig./HP)

  14. Distracted and confused?: selective attention under load.

    Science.gov (United States)

    Lavie, Nilli

    2005-02-01

    The ability to remain focused on goal-relevant stimuli in the presence of potentially interfering distractors is crucial for any coherent cognitive function. However, simply instructing people to ignore goal-irrelevant stimuli is not sufficient for preventing their processing. Recent research reveals that distractor processing depends critically on the level and type of load involved in the processing of goal-relevant information. Whereas high perceptual load can eliminate distractor processing, high load on "frontal" cognitive control processes increases distractor processing. These findings provide a resolution to the long-standing early and late selection debate within a load theory of attention that accommodates behavioural and neuroimaging data within a framework that integrates attention research with executive function.

  15. Study on ant colony optimization for fuel loading pattern problem

    International Nuclear Information System (INIS)

    Kishi, Hironori; Kitada, Takanori

    2013-01-01

    Modified ant colony optimization (ACO) was applied to the in-core fuel loading pattern (LP) optimization problem to minimize the power peaking factor (PPF) in the modeled 1/4 symmetry PWR core. Loading order was found to be important in ACO. Three different loading orders with and without the adjacent effect between fuel assemblies (FAs) were compared, and it was found that the loading order from the central core is preferable because many selections of FAs to be inserted are available in the core center region. LPs were determined from pheromone trail and heuristic information, which is a priori knowledge based on the feature of the problem. Three types of heuristic information were compared to obtain the desirable performance of searching LPs with low PPF. Moreover, mutation operation, such as the genetic algorithm (GA), was introduced into the ACO algorithm to avoid searching similar LPs because heuristic information used in ACO tends to localize the searching space in the LP problem. The performance of ACO with some improvement was compared with those of simulated annealing and GA. In conclusion, good performance can be achieved by setting proper heuristic information and mutation operation parameter in ACO. (author)

  16. Transposing Concentration-Discharge Curves onto Unmonitored Catchments to Estimate Seasonal Nutrient Loads

    Science.gov (United States)

    Minaudo, C.; Moatar, F.; Abbott, B. W.; Dupas, R.; Gascuel-Odoux, C.; Pinay, G.; Roubeix, V.; Danis, P. A.

    2017-12-01

    Many lakes and reservoirs in Europe suffer from severe eutrophication. Accurate quantification of nutrient loads are critical for effective mitigation measures, but this information is often unknown. For example, in France, only 50 out of 481 lakes and reservoirs have national monitoring allowing estimation of interannual nitrogen and phosphorus loads, and even these loads are computed from low-frequency data. To address this lack of data, we developed a straightforward method to predict seasonal loads in lake tributaries. First, we analyzed concentration-discharge (C-Q) curves in monitored catchments and identified slopes, intercepts, and coefficient of variation of the log(C)-log(Q) regressions determined for both low and high flows, separated by the median daily flow [Moatar et al., 2017]. Then, we used stepwise multiple linear regression models to empirically link the characteristics of C-Q curves with a set of catchment descriptors such as land use, lithology, morphology indices, climate, and hydrological indicators. Modeled C-Q relationships were then used to estimate annual and seasonal nutrient loads in nearby and similar unmonitored catchments. We implemented this approach on a large dataset from France where stream flow was surveyed daily and water quality (suspended solids, nitrate, total phosphorus, and orthophosphate concentrations) was measured on a monthly basis at 233 stations over the past 20 years in catchments from 10 to 3000 km². The concentration at the median daily flow (seen here as a metric of the general level of contamination in a catchment) was predicted with uncertainty ranging between 30 and 100 %, depending on the variable. C-Q slopes were predicted with large errors, but a sensitivity analysis was conducted to determine the impact of C-Q slopes uncertainties on computed annual and seasonal loads. This approach allows estimation of seasonal and annual nutrient loads and could be potentially implemented to improve protection and

  17. Association between increase in vertical ground reaction force loading rate and pain level in women with patellofemoral pain after a patellofemoral joint loading protocol.

    Science.gov (United States)

    Briani, Ronaldo Valdir; Pazzinatto, Marcella Ferraz; Waiteman, Marina Cabral; de Oliveira Silva, Danilo; de Azevedo, Fábio Mícolis

    2018-04-11

    The etiology of patellofemoral pain (PFP) is thought to be the result of increased patellofemoral joint (PFJ) load and aberrant lower extremity mechanics, including altered vertical ground reaction forces (VGRF). However, few studies have investigated the association between an increase in pain and VGRF loading rates in the context of PFP. Thus, this study aimed to investigate the immediate effects of PFJ loading on pain and VGRF loading rate, and to see if there is a link between modification of both pain and VGRF loading rate during stair negotiation. Thirty-four women with PFP underwent VGRF analysis during stair negotiation under two conditions: with (condition 2) and without (condition 1) being previously submitted to a PFJ loading protocol in order to or not to exacerbate their knee pain, respectively. The VGRF loading rates were significantly higher in condition 2 (Mean ± standard deviation (SD)=4.0±0.6N/s) compared to condition 1 (Mean±SD=3.6±0.5N/s) during stair ascent and during stair descent (Mean±SD: condition 1=6.3±1.1N/s; condition 2=7.0±1.4N/s). In addition, VGRF loading rates were higher during stair descent compared to stair ascent in both conditions. There were significant correlations between the increase in pain and VGRF loading rate during both tasks. There seemed to be an important relation between the increase in pain and VGRF loading rates in women with PFP. Based on these findings, interventions aimed at reducing VGRF loading rates are important in the context of PFP. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Re-assessing reliability based on survived loads

    NARCIS (Netherlands)

    Schweckendiek, T.

    2011-01-01

    The reliability of flood defenses is often dictated by large uncertainties in the hydraulic loading and the structural resistance. Additional information decreases uncertainty, however, acquiring it is often costly. One source of information, even though in many cases readily available, is hardly

  19. A general method for targeted quantitative cross-linking mass spectrometry

    Science.gov (United States)

    Chemical cross-linking mass spectrometry (XL-MS) provides protein structural information by identifying covalently linked proximal amino acid residues on protein surfaces. The information gained by this technique is complementary to other structural biology methods such as x-ray crystallography, NM...

  20. Linking DMR and TRI Data in the DMR Pollutant Loading Tool ...

    Science.gov (United States)

    ECHO, Enforcement and Compliance History Online, provides compliance and enforcement information for approximately 800,000 EPA-regulated facilities nationwide. ECHO includes permit, inspection, violation, enforcement action, and penalty information about facilities regulated under the Clean Air Act (CAA) Stationary Source Program, Clean Water Act (CWA) National Pollutant Elimination Discharge System (NPDES), and/or Resource Conservation and Recovery Act (RCRA). Information also is provided on surrounding demographics when available.

  1. A linked land-sea modeling framework to inform ridge-to-reef management in high oceanic islands.

    Directory of Open Access Journals (Sweden)

    Jade M S Delevaux

    Full Text Available Declining natural resources have led to a cultural renaissance across the Pacific that seeks to revive customary ridge-to-reef management approaches to protect freshwater and restore abundant coral reef fisheries. Effective ridge-to-reef management requires improved understanding of land-sea linkages and decision-support tools to simultaneously evaluate the effects of terrestrial and marine drivers on coral reefs, mediated by anthropogenic activities. Although a few applications have linked the effects of land cover to coral reefs, these are too coarse in resolution to inform watershed-scale management for Pacific Islands. To address this gap, we developed a novel linked land-sea modeling framework based on local data, which coupled groundwater and coral reef models at fine spatial resolution, to determine the effects of terrestrial drivers (groundwater and nutrients, mediated by human activities (land cover/use, and marine drivers (waves, geography, and habitat on coral reefs. We applied this framework in two 'ridge-to-reef' systems (Hā'ena and Ka'ūpūlehu subject to different natural disturbance regimes, located in the Hawaiian Archipelago. Our results indicated that coral reefs in Ka'ūpūlehu are coral-dominated with many grazers and scrapers due to low rainfall and wave power. While coral reefs in Hā'ena are dominated by crustose coralline algae with many grazers and less scrapers due to high rainfall and wave power. In general, Ka'ūpūlehu is more vulnerable to land-based nutrients and coral bleaching than Hā'ena due to high coral cover and limited dilution and mixing from low rainfall and wave power. However, the shallow and wave sheltered back-reef areas of Hā'ena, which support high coral cover and act as nursery habitat for fishes, are also vulnerable to land-based nutrients and coral bleaching. Anthropogenic sources of nutrients located upstream from these vulnerable areas are relevant locations for nutrient mitigation, such as

  2. Pattern fuel assembly loading system

    International Nuclear Information System (INIS)

    Ahmed, H.J.; Gerkey, K.S.; Miller, T.W.; Wylie, M.E.

    1986-01-01

    This patent describes an interactive system for facilitating preloading of fuel rods into magazines, which comprises: an operator work station adapted for positioning between a supply of fuel rods of predetermined types, and the magazine defining grid locations for a predetermined fuel assembly; display means associated with the work station; scanner means associated with the work station and adapted for reading predetermined information accompanying the fuel rods; a rectangular frame adapted for attachment to one end of the fuel assembly loading magazine; prompter/detector means associated with the frame for detecting insertion of a fuel rod into the magazine; and processing means responsive to the scanner means and the sensing means for prompting the operator via the display means to pre-load the fuel rods into desired grid locations in the magazine. An apparatus is described for facilitating pre-loading of fuel rods in predetermined grid locations of a fuel assembly loading magazine, comprising: a rectangular frame adapted for attachment to one end of the fuel assembly loading magazine; and means associated with the frame for detecting insertion of fuel rods into the magazine

  3. Allostatic load mediates the impact of stress and trauma on physical and mental health in Indigenous Australians.

    Science.gov (United States)

    Sarnyai, Zoltán; Berger, Maximus; Jawan, Isabella

    2016-02-01

    A considerable gap exists in health and social emotional well-being between Indigenous people and non-Indigenous Australians. Recent research in stress neurobiology highlights biological pathways that link early adversity and traumas as well as life stresses to ill health. We argue that the neurobiological stress response and its maladaptive changes, termed allostatic load, provide a useful framework to understand how adversity leads to physical and mental illness in Indigenous people. In this paper we review the biology of allostatic load and make links between stress-induced systemic hormonal, metabolic and immunological changes and physical and mental illnesses. Exposure to chronic stress throughout life results in an increased allostatic load that may contribute to a number of metabolic, cardiovascular and mental disorders that shorten life expectancy in Indigenous Australians. © The Royal Australian and New Zealand College of Psychiatrists 2015.

  4. Load-induced modulation of signal transduction networks.

    Science.gov (United States)

    Jiang, Peng; Ventura, Alejandra C; Sontag, Eduardo D; Merajver, Sofia D; Ninfa, Alexander J; Del Vecchio, Domitilla

    2011-10-11

    Biological signal transduction networks are commonly viewed as circuits that pass along information--in the process amplifying signals, enhancing sensitivity, or performing other signal-processing tasks--to transcriptional and other components. Here, we report on a "reverse-causality" phenomenon, which we call load-induced modulation. Through a combination of analytical and experimental tools, we discovered that signaling was modulated, in a surprising way, by downstream targets that receive the signal and, in doing so, apply what in physics is called a load. Specifically, we found that non-intuitive changes in response dynamics occurred for a covalent modification cycle when load was present. Loading altered the response time of a system, depending on whether the activity of one of the enzymes was maximal and the other was operating at its minimal rate or whether both enzymes were operating at submaximal rates. These two conditions, which we call "limit regime" and "intermediate regime," were associated with increased or decreased response times, respectively. The bandwidth, the range of frequency in which the system can process information, decreased in the presence of load, suggesting that downstream targets participate in establishing a balance between noise-filtering capabilities and a circuit's ability to process high-frequency stimulation. Nodes in a signaling network are not independent relay devices, but rather are modulated by their downstream targets.

  5. Linked data and user interaction

    CERN Document Server

    Cervone, H Frank

    2015-01-01

    This collection of research papers provides extensive information on deploying services, concepts, and approaches for using open linked data from libraries and other cultural heritage institutions. With a special emphasis on how libraries and other cultural heritage institutions can create effective end user interfaces using open, linked data or other datasets. These papers are essential reading for any one interesting in user interface design or the semantic web.

  6. Wear of cross-linked polyethylene against itself: a material suitable for surface replacement of the finger joint.

    Science.gov (United States)

    Sibly, T F; Unsworth, A

    1991-05-01

    Cross-linking of polyethylene (XLPE) has dramatically improved its properties in industrial applications, and it may also have some application in the field of human joint replacement. Additionally it has the advantage of permitting a lower molecular weight base material to be used, so that components may be injection moulded rather than machined. This study therefore investigates the wear resistance of medical grade cross-linked polyethylene (XLPE), cross-linked by a silane-grafting process, with a molecular weight between cross links of 5430 g mol(-1). This first report investigates the wear resistance of XLPE against itself, because for certain joints, such as the metacarpo-phalangeal joint, the material may have a high enough wear resistance to allow both bearing surfaces to be made from it. Tests were carried out both on a reciprocating pin and plate machine with pins loaded at 10 and 40 N and also on a new finger joint simulator, which simulates the loads applied to and the movements of, the metacarpo-phalangeal joint. An average wear rate of 1.8 x 10(-6) mm3 N-1 m-1 was found (range 0.9-2.75 x 10(-6) mm3 N-1 m-1). This is about six times greater than the wear rate of non-cross-linked ultra high molecular weight polyethylene (UHMWPE) against stainless steel, but for applications with low loading, such as the metacarpo-phalangeal joint, this material is shown to have adequate wear resistance. The coefficient of friction was 0.1, which is similar to that of UHMWPE on stainless steel.

  7. A bankruptcy problem approach to load-shedding in multiagent-based microgrid operation.

    Science.gov (United States)

    Kim, Hak-Man; Kinoshita, Tetsuo; Lim, Yujin; Kim, Tai-Hoon

    2010-01-01

    A microgrid is composed of distributed power generation systems (DGs), distributed energy storage devices (DSs), and loads. To maintain a specific frequency in the islanded mode as an important requirement, the control of DGs' output and charge action of DSs are used in supply surplus conditions and load-shedding and discharge action of DSs are used in supply shortage conditions. Recently, multiagent systems for autonomous microgrid operation have been studied. Especially, load-shedding, which is intentional reduction of electricity use, is a critical problem in islanded microgrid operation based on the multiagent system. Therefore, effective schemes for load-shedding are required. Meanwhile, the bankruptcy problem deals with dividing short resources among multiple agents. In order to solve the bankruptcy problem, division rules, such as the constrained equal awards rule (CEA), the constrained equal losses rule (CEL), and the random arrival rule (RA), have been used. In this paper, we approach load-shedding as a bankruptcy problem. We compare load-shedding results by above-mentioned rules in islanded microgrid operation based on wireless sensor network (WSN) as the communication link for an agent's interactions.

  8. Orthodontic informed consent considering information load and serial position effect.

    Science.gov (United States)

    Pawlak, Caroline E; Fields, Henry W; Beck, F Michael; Firestone, Allen R

    2015-03-01

    Previous research has demonstrated that current methods of informed consent are relatively ineffective as shown by poor recall and comprehension by adolescent patients and their parents. The purpose of this study was to determine whether adding a short videotape presentation reiterating the issues related to informed consent to a modified informed consent document that emphasizes a limited number of core and patient-specific custom "chunks" at the beginning of an informed consent presentation improved the recall and comprehension of the risks, benefits, and alternatives of orthodontic treatment. A second objective was to evaluate the current related data for recommendable practices. Seventy patient-parent pairs were randomly divided into 2 groups. The intervention group (group A) patients and parents together reviewed a customized slide show and a short videotape presentation describing the key risks of orthodontic treatment. Group B followed the same protocol without viewing the videotape. All patients and parents were interviewed independently by research assistants using an established measurement tool with open-ended questions. Interviews were transcribed and scored for the appropriateness of responses using a previously established codebook. Lastly, the patients and parents were given 2 reading literacy tests, 1 related to health and 1 with general content followed by the self-administered demographic and psychological state questionnaires. There were no significant differences between the groups for sociodemographic variables. There were no significant differences between the groups for overall recall and comprehension; recall and comprehension for the domains of treatment, risk, and responsibility; and recall and comprehension for core, general, and custom items. The positional effects were limited in impact. When compared with previous studies, these data further demonstrate the benefit of improved readability and audiovisual supplementation with the

  9. Task relevance of emotional information affects anxiety-linked attention bias in visual search.

    Science.gov (United States)

    Dodd, Helen F; Vogt, Julia; Turkileri, Nilgun; Notebaert, Lies

    2017-01-01

    Task relevance affects emotional attention in healthy individuals. Here, we investigate whether the association between anxiety and attention bias is affected by the task relevance of emotion during an attention task. Participants completed two visual search tasks. In the emotion-irrelevant task, participants were asked to indicate whether a discrepant face in a crowd of neutral, middle-aged faces was old or young. Irrelevant to the task, target faces displayed angry, happy, or neutral expressions. In the emotion-relevant task, participants were asked to indicate whether a discrepant face in a crowd of middle-aged neutral faces was happy or angry (target faces also varied in age). Trait anxiety was not associated with attention in the emotion-relevant task. However, in the emotion-irrelevant task, trait anxiety was associated with a bias for angry over happy faces. These findings demonstrate that the task relevance of emotional information affects conclusions about the presence of an anxiety-linked attention bias. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Quantum load balancing in ad hoc networks

    Science.gov (United States)

    Hasanpour, M.; Shariat, S.; Barnaghi, P.; Hoseinitabatabaei, S. A.; Vahid, S.; Tafazolli, R.

    2017-06-01

    This paper presents a novel approach in targeting load balancing in ad hoc networks utilizing the properties of quantum game theory. This approach benefits from the instantaneous and information-less capability of entangled particles to synchronize the load balancing strategies in ad hoc networks. The quantum load balancing (QLB) algorithm proposed by this work is implemented on top of OLSR as the baseline routing protocol; its performance is analyzed against the baseline OLSR, and considerable gain is reported regarding some of the main QoS metrics such as delay and jitter. Furthermore, it is shown that QLB algorithm supports a solid stability gain in terms of throughput which stands a proof of concept for the load balancing properties of the proposed theory.

  11. Uncovering the essential links in online commercial networks

    Science.gov (United States)

    Zeng, Wei; Fang, Meiling; Shao, Junming; Shang, Mingsheng

    2016-09-01

    Recommender systems are designed to effectively support individuals' decision-making process on various web sites. It can be naturally represented by a user-object bipartite network, where a link indicates that a user has collected an object. Recently, research on the information backbone has attracted researchers' interests, which is a sub-network with fewer nodes and links but carrying most of the relevant information. With the backbone, a system can generate satisfactory recommenda- tions while saving much computing resource. In this paper, we propose an enhanced topology-aware method to extract the information backbone in the bipartite network mainly based on the information of neighboring users and objects. Our backbone extraction method enables the recommender systems achieve more than 90% of the accuracy of the top-L recommendation, however, consuming only 20% links. The experimental results show that our method outperforms the alternative backbone extraction methods. Moreover, the structure of the information backbone is studied in detail. Finally, we highlight that the information backbone is one of the most important properties of the bipartite network, with which one can significantly improve the efficiency of the recommender system.

  12. Impedance-based Analysis of DC Link Control in Voltage Source Rectifiers

    DEFF Research Database (Denmark)

    Lu, Dapeng; Wang, Xiongfei; Blaabjerg, Frede

    2018-01-01

    This paper analyzes the dynamics influences of the outer dc link control in the voltage source rectifiers based on the impedance model. The ac-dc interactions are firstly presented by means of full order small signal model in dq frame, which shows the input voltage and load condition are the two...

  13. Loading functions for assessment of water pollution from nonpoint sources. Final report

    International Nuclear Information System (INIS)

    McElroy, A.D.; Chiu, S.Y.; Nebgen, J.W.; Aleti, A.; Bennett, F.W.

    1976-05-01

    Methods for evaluating the quantity of water pollutants generated from nonpoint sources including agriculture, silviculture, construction, mining, runoff from urban areas and rural roads, and terrestrial disposal are developed and compiled for use in water quality planning. The loading functions, plus in some instances emission values, permit calculation of nonpoint source pollutants from available data and information. Natural background was considered to be a source and loading functions were presented to estimate natural or background loads of pollutants. Loading functions/values are presented for average conditions, i.e., annual average loads expressed as metric tons/hectare/year (tons/acre/year). Procedures for estimating seasonal or 30-day maximum and minimum loads are also presented. In addition, a wide variety of required data inputs to loading functions, and delineation of sources of additional information are included in the report. The report also presents an evaluation of limitations and constraints of various methodologies which will enable the user to employ the functions realistically

  14. Testing and modeling of cyclically loaded rock anchors

    Directory of Open Access Journals (Sweden)

    Joar Tistel

    2017-12-01

    Full Text Available The Norwegian Public Roads Administration (NPRA is planning for an upgrade of the E39 highway route at the westcoast of Norway. Fixed links shall replace ferries at seven fjord crossings. Wide spans and large depths at the crossings combined with challenging subsea topography and environmental loads call for an extension of existing practice. A variety of bridge concepts are evaluated in the feasibility study. The structures will experience significant loads from deadweight, traffic and environment. Anchoring of these forces is thus one of the challenges met in the project. Large-size subsea rock anchors are considered a viable alternative. These can be used for anchoring of floating structures but also with the purpose of increasing capacity of fixed structures. This paper presents first a thorough study of factors affecting rock anchor bond capacity. Laboratory testing of rock anchors subjected to cyclic loading is thereafter presented. Finally, the paper presents a model predicting the capacity of a rock anchor segment, in terms of a ribbed bar, subjected to a cyclic load history. The research assumes a failure mode occurring in the interface between the rock anchor and the surrounding grout. The constitutive behavior of the bonding interface is investigated for anchors subjected to cyclic one-way tensile loads. The model utilizes the static bond capacity curve as a basis, defining the ultimate bond τbu and the slip s1 at τbu. A limited number of input parameters are required to apply the model. The model defines the bond-slip behavior with the belonging rock anchor capacity depending on the cyclic load level (τmax cy/τbu, the cyclic load ratio (R = τmin cy/τmax cy, and the number of load cycles (N. The constitutive model is intended to model short anchor lengths representing an incremental length of a complete rock anchor.

  15. Linking to MedlinePlus

    Science.gov (United States)

    ... want to link patients or healthcare providers from electronic health record (EHR) systems to relevant MedlinePlus information, use MedlinePlus ... updates Subscribe to RSS Follow us Disclaimers Copyright Privacy Accessibility Quality Guidelines Viewers & Players MedlinePlus Connect for ...

  16. Dual adjacency matrix : exploring link groups in dense networks

    NARCIS (Netherlands)

    Dinkla, K.; Henry Riche, N.; Westenberg, M.A.

    2015-01-01

    Node grouping is a common way of adding structure and information to networks that aids their interpretation. However, certain networks benefit from the grouping of links instead of nodes. Link communities, for example, are a form of link groups that describe high-quality overlapping node

  17. Load monitoring program: Status and results report. Volume 1: Summary

    International Nuclear Information System (INIS)

    1994-06-01

    British Columbia Hydro conducts a monitoring program to provide information on customer needs and values for planning; to measure customer response, energy savings impacts, and load shape impacts due to changes in rate level, rate restructuring, and Power Smart programs; to estimate end-use consumption and load shapes by customer class; and to provide load information for distribution and system load studies. To achieve these objectives, the monitoring program tracks the characteristics and energy use patterns of a sample of BC Hydro residential, commercial, and industrial customers over a period of several years. The entire sample will be surveyed periodically to obtain information on changes in building characteristics, equipment stocks, and energy-use behavior and attitudes. A report is provided on the status of monitoring program activities and some results obtained in 1993/94. For the residential sector, the results include typical load profiles, end-user demographics, and extent of electric space heating and water heating. In the commercial sector, customers were divided into two main groups. The large-building group was relatively well organized in terms of energy needs and participated in Power Smart programs. The small-building group was relatively energy-inefficient and relatively unaware of Power Smart programs. 43 figs., 15 tabs

  18. Musical ability and non-native speech-sound processing are linked through sensitivity to pitch and spectral information.

    Science.gov (United States)

    Kempe, Vera; Bublitz, Dennis; Brooks, Patricia J

    2015-05-01

    Is the observed link between musical ability and non-native speech-sound processing due to enhanced sensitivity to acoustic features underlying both musical and linguistic processing? To address this question, native English speakers (N = 118) discriminated Norwegian tonal contrasts and Norwegian vowels. Short tones differing in temporal, pitch, and spectral characteristics were used to measure sensitivity to the various acoustic features implicated in musical and speech processing. Musical ability was measured using Gordon's Advanced Measures of Musical Audiation. Results showed that sensitivity to specific acoustic features played a role in non-native speech-sound processing: Controlling for non-verbal intelligence, prior foreign language-learning experience, and sex, sensitivity to pitch and spectral information partially mediated the link between musical ability and discrimination of non-native vowels and lexical tones. The findings suggest that while sensitivity to certain acoustic features partially mediates the relationship between musical ability and non-native speech-sound processing, complex tests of musical ability also tap into other shared mechanisms. © 2014 The British Psychological Society.

  19. Dose-dependent utilisation of casein-linked lysinoalanine, N(epsilon)-fructoselysine and N(epsilon)-carboxymethyllysine in rats.

    Science.gov (United States)

    Somoza, Veronika; Wenzel, Elisabeth; Weiss, Carola; Clawin-Rädecker, Ingrid; Grübel, Nadine; Erbersdobler, Helmut F

    2006-09-01

    During the heat treatment of protein-containing foods, the amino acid lysine is most prone to undergo chemical reactions in the course of amino acid cross-linking or Maillard reactions. Among the reaction products formed, lysinoalanine (LAL), N(epsilon)-fructoselysine (FL) and N(epsilon)-carboxymethyllysine (CML) are those which serve as sensitive markers for the heat treatment applied. From a nutritional perspective, these compounds are ingested with the diet in considerable amounts but information about their metabolic transit and putative in vivo effects is scarce. In the present study, casein-linked LAL, FL and CML were administered to rats in two different doses for 10 days. Quantitation of LAL, FL and CML in plasma, tissue and faeces samples revealed that the kidneys are the predominant sites of accumulation and excretion. The maximum percent of dietary LAL, FL and CML excreted in the urine was 5.6, 5.2 and 29%, whereas the respective recoveries in the kidneys were 0.02, 26 and 1.4%. The plasma and tissue analyses revealed that the endogenous load of either compound is increased by its dietary intake. But the dose-dependent utilisation of dietary protein-linked LAL, FL and CML in rats has been demonstrated for the first time to vary substantially from each other.

  20. Low-Load Space Conditioning Needs Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Puttagunta, Srikanth [Consortium for Advanced Residential Buildings, Norwalk, CT (United States)

    2015-05-01

    With limited low-load options in the HVAC market, many new-construction housing units are being fitted with oversized equipment - thus facing penalties in system efficiency, comfort, and cost. To bridge the gap between currently available HVAC equipment and the rising demand for low-load HVAC equipment in the marketplace, HVAC equipment manufacturers need to be fully aware of multifamily buildings and single-family homes market needs. Over the past decade, Steven Winter Associates, Inc. (SWA) has provided certification and consulting services on hundreds of housing projects and has accrued a large pool of data. CARB compiled and analyzed these data to see what the thermal load ranges are in various multifamily apartments and attached single-family home types (duplex and townhouse). In total, design loads from 941 dwellings from SWA's recent multifamily and attached single-family work across the Northeast and Mid-Atlantic were analyzed. Information on the dwelling characteristics, design loads, and the specifications of installed mechanical equipment were analyzed to determine any trends that exist within the dataset.

  1. The cost of making an eye movement: A direct link between visual working memory and saccade execution.

    Science.gov (United States)

    Schut, Martijn J; Van der Stoep, Nathan; Postma, Albert; Van der Stigchel, Stefan

    2017-06-01

    To facilitate visual continuity across eye movements, the visual system must presaccadically acquire information about the future foveal image. Previous studies have indicated that visual working memory (VWM) affects saccade execution. However, the reverse relation, the effect of saccade execution on VWM load is less clear. To investigate the causal link between saccade execution and VWM, we combined a VWM task and a saccade task. Participants were instructed to remember one, two, or three shapes and performed either a No Saccade-, a Single Saccade- or a Dual (corrective) Saccade-task. The results indicate that items stored in VWM are reported less accurately if a single saccade-or a dual saccade-task is performed next to retaining items in VWM. Importantly, the loss of response accuracy for items retained in VWM by performing a saccade was similar to committing an extra item to VWM. In a second experiment, we observed no cost of executing a saccade for auditory working memory performance, indicating that executing a saccade exclusively taxes the VWM system. Our results suggest that the visual system presaccadically stores the upcoming retinal image, which has a similar VWM load as committing one extra item to memory and interferes with stored VWM content. After the saccade, the visual system can retrieve this item from VWM to evaluate saccade accuracy. Our results support the idea that VWM is a system which is directly linked to saccade execution and promotes visual continuity across saccades.

  2. Active link selection for efficient semi-supervised community detection

    Science.gov (United States)

    Yang, Liang; Jin, Di; Wang, Xiao; Cao, Xiaochun

    2015-01-01

    Several semi-supervised community detection algorithms have been proposed recently to improve the performance of traditional topology-based methods. However, most of them focus on how to integrate supervised information with topology information; few of them pay attention to which information is critical for performance improvement. This leads to large amounts of demand for supervised information, which is expensive or difficult to obtain in most fields. For this problem we propose an active link selection framework, that is we actively select the most uncertain and informative links for human labeling for the efficient utilization of the supervised information. We also disconnect the most likely inter-community edges to further improve the efficiency. Our main idea is that, by connecting uncertain nodes to their community hubs and disconnecting the inter-community edges, one can sharpen the block structure of adjacency matrix more efficiently than randomly labeling links as the existing methods did. Experiments on both synthetic and real networks demonstrate that our new approach significantly outperforms the existing methods in terms of the efficiency of using supervised information. It needs ~13% of the supervised information to achieve a performance similar to that of the original semi-supervised approaches. PMID:25761385

  3. OhioLINK: Implementing Integrated Library Services across Institutional Boundaries.

    Science.gov (United States)

    Hawks, Carol Pitts

    1995-01-01

    Discusses the implementation of the OhioLINK (Ohio Library and Information Network) system, an integrated library system linking 23 public and private academic institutions and the Ohio State Library. Topics include a history of OhioLINK; organizational structure; decision-making procedures; public relations strategies; cooperative circulation;…

  4. A design procedure for the phase-controlled parallel-loaded resonant inverter

    Science.gov (United States)

    King, Roger J.

    1989-01-01

    High-frequency-link power conversion and distribution based on a resonant inverter (RI) has been recently proposed. The design of several topologies is reviewed, and a simple approximate design procedure is developed for the phase-controlled parallel-loaded RI. This design procedure seeks to ensure the benefits of resonant conversion and is verified by data from a laboratory 2.5 kVA, 20-kHz converter. A simple phasor analysis is introduced as a useful approximation for design purposes. The load is considered to be a linear impedance (or an ac current sink). The design procedure is verified using a 2.5-kVA 20-kHz RI. Also obtained are predictable worst-case ratings for each component of the resonant tank circuit and the inverter switches. For a given load VA requirement, below-resonance operation is found to result in a significantly lower tank VA requirement. Under transient conditions such as load short-circuit, a reversal of the expected commutation sequence is possible.

  5. Transparent ICD and DRG coding using information technology: linking and associating information sources with the eXtensible Markup Language.

    Science.gov (United States)

    Hoelzer, Simon; Schweiger, Ralf K; Dudeck, Joachim

    2003-01-01

    With the introduction of ICD-10 as the standard for diagnostics, it becomes necessary to develop an electronic representation of its complete content, inherent semantics, and coding rules. The authors' design relates to the current efforts by the CEN/TC 251 to establish a European standard for hierarchical classification systems in health care. The authors have developed an electronic representation of ICD-10 with the eXtensible Markup Language (XML) that facilitates integration into current information systems and coding software, taking different languages and versions into account. In this context, XML provides a complete processing framework of related technologies and standard tools that helps develop interoperable applications. XML provides semantic markup. It allows domain-specific definition of tags and hierarchical document structure. The idea of linking and thus combining information from different sources is a valuable feature of XML. In addition, XML topic maps are used to describe relationships between different sources, or "semantically associated" parts of these sources. The issue of achieving a standardized medical vocabulary becomes more and more important with the stepwise implementation of diagnostically related groups, for example. The aim of the authors' work is to provide a transparent and open infrastructure that can be used to support clinical coding and to develop further software applications. The authors are assuming that a comprehensive representation of the content, structure, inherent semantics, and layout of medical classification systems can be achieved through a document-oriented approach.

  6. Cognitive task load in a naval ship control centre: from identification to prediction.

    Science.gov (United States)

    Grootjen, M; Neerincx, M A; Veltman, J A

    Deployment of information and communication technology will lead to further automation of control centre tasks and an increasing amount of information to be processed. A method for establishing adequate levels of cognitive task load for the operators in such complex environments has been developed. It is based on a model distinguishing three load factors: time occupied, task-set switching, and level of information processing. Application of the method resulted in eight scenarios for eight extremes of task load (i.e. low and high values for each load factor). These scenarios were performed by 13 teams in a high-fidelity control centre simulator of the Royal Netherlands Navy. The results show that the method provides good prediction of the task load that will actually appear in the simulator. The model allowed identification of under- and overload situations showing negative effects on operator performance corresponding to controlled experiments in a less realistic task environment. Tools proposed to keep the operator at an optimum task load are (adaptive) task allocation and interface support.

  7. Neural effects of cognitive control load on auditory selective attention.

    Science.gov (United States)

    Sabri, Merav; Humphries, Colin; Verber, Matthew; Liebenthal, Einat; Binder, Jeffrey R; Mangalathu, Jain; Desai, Anjali

    2014-08-01

    Whether and how working memory disrupts or alters auditory selective attention is unclear. We compared simultaneous event-related potentials (ERP) and functional magnetic resonance imaging (fMRI) responses associated with task-irrelevant sounds across high and low working memory load in a dichotic-listening paradigm. Participants performed n-back tasks (1-back, 2-back) in one ear (Attend ear) while ignoring task-irrelevant speech sounds in the other ear (Ignore ear). The effects of working memory load on selective attention were observed at 130-210ms, with higher load resulting in greater irrelevant syllable-related activation in localizer-defined regions in auditory cortex. The interaction between memory load and presence of irrelevant information revealed stronger activations primarily in frontal and parietal areas due to presence of irrelevant information in the higher memory load. Joint independent component analysis of ERP and fMRI data revealed that the ERP component in the N1 time-range is associated with activity in superior temporal gyrus and medial prefrontal cortex. These results demonstrate a dynamic relationship between working memory load and auditory selective attention, in agreement with the load model of attention and the idea of common neural resources for memory and attention. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Study of a Car Body Tilting System Using a Variable Link Mechanism: Fundamental Characteristics of Pendulum Motion and Strategy for Perfect Tilting

    Science.gov (United States)

    Yoshida, Hidehisa; Nagai, Masao

    This paper analyzes the fundamental dynamic characteristics of a tilting railway vehicle using a variable link mechanism for compensating both the lateral acceleration experienced by passengers and the wheel load imbalance between the inner and outer rails. The geometric relations between the center of rotation, the center of gravity, and the positions of all four links of the tilting system are analyzed. Then, equations of the pendulum motions of the railway vehicle body with a four-link mechanism are derived. A theoretically discussion is given on the geometrical shapes employed in the link mechanism that can simultaneously provide zero lateral acceleration and zero wheel load fluctuation. Then, the perfect tilting condition, which is the control target of the feedforward tilting control, is derived from the linear equation of tilting motion.

  9. Dynamics and mechanics of bed-load tracer particles

    Directory of Open Access Journals (Sweden)

    C. B. Phillips

    2014-12-01

    Full Text Available Understanding the mechanics of bed load at the flood scale is necessary to link hydrology to landscape evolution. Here we report on observations of the transport of coarse sediment tracer particles in a cobble-bedded alluvial river and a step-pool bedrock tributary, at the individual flood and multi-annual timescales. Tracer particle data for each survey are composed of measured displacement lengths for individual particles, and the number of tagged particles mobilized. For single floods we find that measured tracer particle displacement lengths are exponentially distributed; the number of mobile particles increases linearly with peak flood Shields stress, indicating partial bed load transport for all observed floods; and modal displacement distances scale linearly with excess shear velocity. These findings provide quantitative field support for a recently proposed modeling framework based on momentum conservation at the grain scale. Tracer displacement is weakly negatively correlated with particle size at the individual flood scale; however cumulative travel distance begins to show a stronger inverse relation to grain size when measured over many transport events. The observed spatial sorting of tracers approaches that of the river bed, and is consistent with size-selective deposition models and laboratory experiments. Tracer displacement data for the bedrock and alluvial channels collapse onto a single curve – despite more than an order of magnitude difference in channel slope – when variations of critical Shields stress and flow resistance between the two are accounted for. Results show how bed load dynamics may be predicted from a record of river stage, providing a direct link between climate and sediment transport.

  10. Potential effects of the introduction of the discrete address beacon system data link on air/ground information transfer problems

    Science.gov (United States)

    Grayson, R. L.

    1981-01-01

    This study of Aviation Safety Reporting System reports suggests that benefits should accure from implementation of discrete address beacon system data link. The phase enhanced terminal information system service is expected to provide better terminal information than present systems by improving currency and accuracy. In the exchange of air traffic control messages, discrete address insures that only the intended recipient receives and acts on a specific message. Visual displays and printer copy of messages should mitigate many of the reported problems associated with voice communications. The problems that remain unaffected include error in addressing the intended recipient and messages whose content is wrong but are otherwise correct as to format and reasonableness.

  11. Effectiveness of trimethylopropane trimethacrylate for the electron-beam-irradiation-induced cross-linking of polylactic acid

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Hon-Meng [Department of Chemical Engineering, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jalan Genting Kelang, 53300 Setapak, Kuala Lumpur (Malaysia); Bee, Soo-Tueen, E-mail: beest@utar.edu.my [Department of Chemical Engineering, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jalan Genting Kelang, 53300 Setapak, Kuala Lumpur (Malaysia); Ratnam, C.T. [Radiation Processing Technology Division, Malaysian Nuclear Agency, Bangi, 43000 Kajang, Selangor (Malaysia); Sin, Lee Tin; Phang, Yee-Yao; Tee, Tiam-Ting [Department of Chemical Engineering, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jalan Genting Kelang, 53300 Setapak, Kuala Lumpur (Malaysia); Rahmat, A.R. [Department of Polymer Engineering, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 UTM Skudai, Johor (Malaysia)

    2014-01-15

    Highlights: • Investigation of trimethylopropane trimethacrylate (TMPTMA) on electron beam irradiated PLA. • Irradiated PLA blends were weakened by incorporation of high amount of TMPTMA. • TMPTMA interacts with polymer free radicals to build crosslinking network. -- Abstract: The purpose of this research was to investigate the effects of various loading levels of trimethylopropane trimethacrylate (TMPTMA) on the properties of polylactic acid (PLA) cross-linked via electron-beam irradiation. PLA was compounded with 3–5 wt.% of TMPTMA to induce cross-linking upon subjection to electron-beam irradiation doses of 25–250 kGy. The physical properties of the PLA samples were characterised by means of X-ray diffraction, gel fraction and scanning electron microscopy analyses on fractured surfaces after tensile tests. The presence of TMPTMA in PLA was found to effectively increase the crystallite size and gel fraction. However, higher loading levels of TMPTMA could compromise the properties of the PLA/TMPTMA samples, indicating that a larger amount of monomer free radicals might promote degradation within the substantially cross-linked amorphous phase. Irradiation-induced cross-linking in the samples could improve the cross-linking density while decreasing the elongation and interfering with the crystallisation. These effects are caused by the intensive irradiation-induced chain scission that is responsible for the deterioration of the mechanical and crystalline properties of the samples.

  12. Effectiveness of trimethylopropane trimethacrylate for the electron-beam-irradiation-induced cross-linking of polylactic acid

    International Nuclear Information System (INIS)

    Ng, Hon-Meng; Bee, Soo-Tueen; Ratnam, C.T.; Sin, Lee Tin; Phang, Yee-Yao; Tee, Tiam-Ting; Rahmat, A.R.

    2014-01-01

    Highlights: • Investigation of trimethylopropane trimethacrylate (TMPTMA) on electron beam irradiated PLA. • Irradiated PLA blends were weakened by incorporation of high amount of TMPTMA. • TMPTMA interacts with polymer free radicals to build crosslinking network. -- Abstract: The purpose of this research was to investigate the effects of various loading levels of trimethylopropane trimethacrylate (TMPTMA) on the properties of polylactic acid (PLA) cross-linked via electron-beam irradiation. PLA was compounded with 3–5 wt.% of TMPTMA to induce cross-linking upon subjection to electron-beam irradiation doses of 25–250 kGy. The physical properties of the PLA samples were characterised by means of X-ray diffraction, gel fraction and scanning electron microscopy analyses on fractured surfaces after tensile tests. The presence of TMPTMA in PLA was found to effectively increase the crystallite size and gel fraction. However, higher loading levels of TMPTMA could compromise the properties of the PLA/TMPTMA samples, indicating that a larger amount of monomer free radicals might promote degradation within the substantially cross-linked amorphous phase. Irradiation-induced cross-linking in the samples could improve the cross-linking density while decreasing the elongation and interfering with the crystallisation. These effects are caused by the intensive irradiation-induced chain scission that is responsible for the deterioration of the mechanical and crystalline properties of the samples

  13. The Øresund Link

    DEFF Research Database (Denmark)

    Møller, Jacob Steen

    "Øresundsbron" is the combined bridge and tunnel connecting Denmark and Sweden adjacent to Copenhagen. Øresundsbron was built and is operated by a consortium owned jointly by the Danish and Swedish states. The Link was inaugurated 1 July 2000 by the Queen of Denmark and the King of Sweden. The 16......-km link across the Sound could potentially impact the water exchange between the Baltic Sea and the North Sea, and the dredging activities during construction were a threat to the local marine environment. The public interest in the environmental issues together with a pro-active environmental policy...... of hydrodynamic modelling, on line monitoring and access to all environmental information through a GIS based information system. The public attitude towards the project in general and the environmental impact in particular shifted from a very sceptical one at the beginning of the project to a very positive one...

  14. The Statistical Properties of Host Load

    Directory of Open Access Journals (Sweden)

    Peter A. Dinda

    1999-01-01

    Full Text Available Understanding how host load changes over time is instrumental in predicting the execution time of tasks or jobs, such as in dynamic load balancing and distributed soft real‐time systems. To improve this understanding, we collected week‐long, 1 Hz resolution traces of the Digital Unix 5 second exponential load average on over 35 different machines including production and research cluster machines, compute servers, and desktop workstations. Separate sets of traces were collected at two different times of the year. The traces capture all of the dynamic load information available to user‐level programs on these machines. We present a detailed statistical analysis of these traces here, including summary statistics, distributions, and time series analysis results. Two significant new results are that load is self‐similar and that it displays epochal behavior. All of the traces exhibit a high degree of self‐similarity with Hurst parameters ranging from 0.73 to 0.99, strongly biased toward the top of that range. The traces also display epochal behavior in that the local frequency content of the load signal remains quite stable for long periods of time (150–450 s mean and changes abruptly at epoch boundaries. Despite these complex behaviors, we have found that relatively simple linear models are sufficient for short‐range host load prediction.

  15. Assessment of Optimal Flexibility in Ensemble of Frequency Responsive Loads

    Energy Technology Data Exchange (ETDEWEB)

    Kundu, Soumya; Hansen, Jacob; Lian, Jianming; Kalsi, Karanjit

    2018-04-19

    Potential of electrical loads in providing grid ancillary services is often limited due to the uncertainties associated with the load behavior. A knowledge of the expected uncertainties with a load control program would invariably yield to better informed control policies, opening up the possibility of extracting the maximal load control potential without affecting grid operations. In the context of frequency responsive load control, a probabilistic uncertainty analysis framework is presented to quantify the expected error between the target and actual load response, under uncertainties in the load dynamics. A closed-form expression of an optimal demand flexibility, minimizing the expected error in actual and committed flexibility, is provided. Analytical results are validated through Monte Carlo simulations of ensembles of electric water heaters.

  16. Stimulus recognition occurs under high perceptual load: Evidence from correlated flankers.

    Science.gov (United States)

    Cosman, Joshua D; Mordkoff, J Toby; Vecera, Shaun P

    2016-12-01

    A dominant account of selective attention, perceptual load theory, proposes that when attentional resources are exhausted, task-irrelevant information receives little attention and goes unrecognized. However, the flanker effect-typically used to assay stimulus identification-requires an arbitrary mapping between a stimulus and a response. We looked for failures of flanker identification by using a more-sensitive measure that does not require arbitrary stimulus-response mappings: the correlated flankers effect. We found that flanking items that were task-irrelevant but that correlated with target identity produced a correlated flanker effect. Participants were faster on trials in which the irrelevant flanker had previously correlated with the target than when it did not. Of importance, this correlated flanker effect appeared regardless of perceptual load, occurring even in high-load displays that should have abolished flanker identification. Findings from a standard flanker task replicated the basic perceptual load effect, with flankers not affecting response times under high perceptual load. Our results indicate that task-irrelevant information can be processed to a high level (identification), even under high perceptual load. This challenges a strong account of high perceptual load effects that hypothesizes complete failures of stimulus identification under high perceptual load. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  17. Long Lifetime DC-Link Voltage Stabilization Module for Smart Grid Application

    DEFF Research Database (Denmark)

    Wang, Huai; Chung, Henry; Liu, Wenchao

    2012-01-01

    Power converters enable efficient and flexible control and conversion of electric energy among different smart grid players (i.e. producers, energy storage systems, and loads). One of the expected features of smart grid is that it will be more reliable compared to conventional grid. However, power...... converters are one kind of the lifetime limiting components applied in smart grid. One of the major causes is the malfunction of electrolytic capacitors (E-Caps) which are widely used for stabilizing the dc-link voltage in various types of power converters applied in smart grid. A dc-link module is therefore...

  18. Resonance reduction for AC drives with small capacitance in the DC link

    DEFF Research Database (Denmark)

    Máthé, Lászlo; Török, Lajos; Wang, Dong

    2016-01-01

    Pulse Width Modulated AC drives equipped with small DC-link capacitor are becoming an attractive solution for electric drive applications with moderate requirements for shaft dynamic performance. However, when these drives are fed from a weak grid a resonance between the line side impedance...... and the DC-link capacitor appears. Due to this resonance, the THD and the partially weighted harmonic distortion of the line currents are increased, which may rise compatibility problems with the AC line harmonic standards. By using vector control the motor drive is transformed into a constant power load...

  19. International Virtual Observatory System for Water Resources Information

    Science.gov (United States)

    Leinenweber, Lewis; Bermudez, Luis

    2013-04-01

    Sharing, accessing, and integrating hydrologic and climatic data have been identified as a critical need for some time. The current state of data portals, standards, technologies, activities, and expertise can be leverage to develop an initial operational capability for a virtual observatory system. This system will allow to link observations data with stream networks and models, and to solve semantic inconsistencies among communities. Prototyping a virtual observatory system is an inter-disciplinary, inter-agency and international endeavor. The Open Geospatial Consortium (OGC) within the OGC Interoperability Program provides the process and expertise to run such collaborative effort. The OGC serves as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The project coordinated by OGC that is advancing an international virtual observatory system for water resources information is called Climatology-Hydrology Information Sharing Pilot, Phase 1 (CHISP-1). It includes observations and forecasts in the U.S. and Canada levering current networks and capabilities. It is designed to support the following use cases: 1) Hydrologic modeling for historical and near-future stream flow and groundwater conditions. Requires the integration of trans-boundary stream flow and groundwater well data, as well as national river networks (US NHD and Canada NHN) from multiple agencies. Emphasis will be on time series data and real-time flood monitoring. 2) Modeling and assessment of nutrient load into the lakes. Requires accessing water-quality data from multiple agencies and integrating with stream flow information for calculating loads. Emphasis on discrete sampled water quality observations, linking those to specific NHD stream reaches and catchments, and additional metadata for sampled data. The key objectives of these use cases are: 1) To link

  20. Effects of microbial loading and sporulation temperature on atmospheric plasma inactivation of Bacillus subtilis spores

    Science.gov (United States)

    Deng, X. T.; Shi, J. J.; Shama, G.; Kong, M. G.

    2005-10-01

    Current inactivation studies of Bacillus subtilis spores using atmospheric-pressure glow discharges (APGD) do not consider two important factors, namely microbial loading at the surface of a substrate and sporulation temperature. Yet these are known to affect significantly microbial resistance to heat and hydrogen peroxide. This letter investigates effects of microbial loading and sporulation temperature on spore resistance to APGD. It is shown that microbial loading can lead to a stacking structure as a protective shield against APGD treatment and that high sporulation temperature increases spore resistance by altering core water content and cross-linked muramic acid content of B. subtilis spores.

  1. Linked data querying through FCA-based schema indexing

    OpenAIRE

    Brosius, Dominik; Staab, Steffen

    2016-01-01

    The effciency of SPARQL query evaluation against Linked Open Data may benefit from schema-based indexing. However, many data items come with incomplete schema information or lack schema descriptions entirely. In this position paper, we outline an approach to an indexing of linked data graphs based on schemata induced through Formal Concept Analysis. We show how to map queries onto RDF graphs based on such derived schema information. We sketch next steps for realizing and optimizing the sugges...

  2. INFLUENCE OF INTERMITTENT CYCLIC LOADING ON REINFORCED CONCRETE RESISTANCE MODEL

    Directory of Open Access Journals (Sweden)

    Vasyl Karpiuk

    2017-01-01

    Full Text Available This article describes the study of reinforced concrete span bending structures under conditions of high-level cyclic loading. Previous studies on the development of physical models of bending reinforced concrete element fatigue resistance, cyclic effect of lateral forces, and methods of calculation, are important and appropriate owing to certain features and the essential specificity of the mentioned loading type. These primarily include the nonlinearity of deformation, damage accumulation in the form of fatigue micro- and macro-cracks, and exhausting destruction of construction materials. In this paper, key expressions determining the endurance limits of concrete, longitudinal reinforcement, and anchoring longitudinal reinforcement, which contribute to endurance throughout the entire construction, are considered. Establishing a link between stresses in the elements and deformations in the element under conditions of cyclic loading action is of equal importance because of the presence of cyclic stress-induced creep deformation.

  3. Auditory perceptual load: A review.

    Science.gov (United States)

    Murphy, Sandra; Spence, Charles; Dalton, Polly

    2017-09-01

    Selective attention is a crucial mechanism in everyday life, allowing us to focus on a portion of incoming sensory information at the expense of other less relevant stimuli. The circumstances under which irrelevant stimuli are successfully ignored have been a topic of scientific interest for several decades now. Over the last 20 years, the perceptual load theory (e.g. Lavie, 1995) has provided one robust framework for understanding these effects within the visual modality. The suggestion is that successful selection depends on the perceptual demands imposed by the task-relevant information. However, less research has addressed the question of whether the same principles hold in audition and, to date, the existing literature provides a mixed picture. Here, we review the evidence for and against the applicability of perceptual load theory in hearing, concluding that this question still awaits resolution. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  4. NELS 2.0 - A general system for enterprise wide information management

    Science.gov (United States)

    Smith, Stephanie L.

    1993-01-01

    NELS, the NASA Electronic Library System, is an information management tool for creating distributed repositories of documents, drawings, and code for use and reuse by the aerospace community. The NELS retrieval engine can load metadata and source files of full text objects, perform natural language queries to retrieve ranked objects, and create links to connect user interfaces. For flexibility, the NELS architecture has layered interfaces between the application program and the stored library information. The session manager provides the interface functions for development of NELS applications. The data manager is an interface between session manager and the structured data system. The center of the structured data system is the Wide Area Information Server. This system architecture provides access to information across heterogeneous platforms in a distributed environment. There are presently three user interfaces that connect to the NELS engine; an X-Windows interface, and ASCII interface and the Spatial Data Management System. This paper describes the design and operation of NELS as an information management tool and repository.

  5. PC-Link historical data base system MODCOMP/IBM at link for neutral particle beam operation

    International Nuclear Information System (INIS)

    Thurgood, P.

    1989-01-01

    PC-Link is a combination of hardware and software that connects an IBM PC/AT to a MODCOMP minicomputer. It is designed as an aid to the Neutral Beam operations coordinator during injection into the DIII-D tokamak project. An IBM PC/AT is linked to 4 MODCOMP realtime acquisition systems, each of which controls 2 neutral particle beam sources. At various points in the shot sequence, data is sent to the IBM PC/AT. This data can then be integrated with the data from the other sources into tables or graphics displays for use by the Beam Coordinator. In this way, the coordinator gets realtime feedback on the relative settings and performance of the sources and can observe trends within a particular source at one location. The PC-Link is used for observing relative timing information and for post shot historical archiving. The concept of the PC-Link was originally proposed several years ago. In April 1988, in-house implementation of the link software was begun. The PC-Link receives approximately 2 Kbytes of data per source per shot. This data is converted from MODCOMP format to IBM PC format and archived to disk. The last 280 shots per source are stored to disk to observe trends. The data can be displayed in a number of formats depending upon the situation. For example, prior to a shot, the beam MODCOMPs are sent timing information from the DIII-D tokamak control system. This data is echoed on the PC in a graphical representation displaying all 8 sources. At the end of the shot, the actual running times are displayed along with the requested settings. Any subset of the Historical data may be displayed either graphically or in tables for realtime comparisons between sources. 4 figs

  6. The SAIL databank: linking multiple health and social care datasets

    Directory of Open Access Journals (Sweden)

    Ford David V

    2009-01-01

    Full Text Available Abstract Background Vast amounts of data are collected about patients and service users in the course of health and social care service delivery. Electronic data systems for patient records have the potential to revolutionise service delivery and research. But in order to achieve this, it is essential that the ability to link the data at the individual record level be retained whilst adhering to the principles of information governance. The SAIL (Secure Anonymised Information Linkage databank has been established using disparate datasets, and over 500 million records from multiple health and social care service providers have been loaded to date, with further growth in progress. Methods Having established the infrastructure of the databank, the aim of this work was to develop and implement an accurate matching process to enable the assignment of a unique Anonymous Linking Field (ALF to person-based records to make the databank ready for record-linkage research studies. An SQL-based matching algorithm (MACRAL, Matching Algorithm for Consistent Results in Anonymised Linkage was developed for this purpose. Firstly the suitability of using a valid NHS number as the basis of a unique identifier was assessed using MACRAL. Secondly, MACRAL was applied in turn to match primary care, secondary care and social services datasets to the NHS Administrative Register (NHSAR, to assess the efficacy of this process, and the optimum matching technique. Results The validation of using the NHS number yielded specificity values > 99.8% and sensitivity values > 94.6% using probabilistic record linkage (PRL at the 50% threshold, and error rates were Conclusion With the infrastructure that has been put in place, the reliable matching process that has been developed enables an ALF to be consistently allocated to records in the databank. The SAIL databank represents a research-ready platform for record-linkage studies.

  7. A Bankruptcy Problem Approach to Load-shedding in Multiagent-based Microgrid Operation

    Directory of Open Access Journals (Sweden)

    Yujin Lim

    2010-09-01

    Full Text Available A microgrid is composed of distributed power generation systems (DGs, distributed energy storage devices (DSs, and loads. To maintain a specific frequency in the islanded mode as an important requirement,  the control of DGs’ output and charge action of DSs are used in supply surplus conditions and load-shedding and discharge action of DSs are used in supply shortage conditions. Recently, multiagent systems for autonomous microgrid operation have been studied. Especially, load-shedding, which is intentional reduction of electricity use, is a critical problem in islanded microgrid operation based on the multiagent system. Therefore, effective schemes for load-shedding are required. Meanwhile, the bankruptcy problem deals with dividing short resources among multiple agents. In order to solve the bankruptcy problem, division rules, such as the constrained equal awards rule (CEA, the constrained equal losses rule (CEL, and the random arrival rule (RA, have been used. In this paper, we approach load-shedding as a bankruptcy problem. We compare load-shedding results by above-mentioned rules in islanded microgrid operation based on wireless sensor network (WSN as the communication link for an agent’s interactions.

  8. Bibliometric analysis of scientific production about Linked Data

    Directory of Open Access Journals (Sweden)

    Leandro Dal Pizzol

    2015-09-01

    Full Text Available Introduction: Since Tim Berners-Lee coined the term Linked Data in 2006, many studies have emerged based on this initiative. Whether in the form of information access initiatives, whether in applications based on this data type, the interest in this new way to publish and consume information on the Web is increasingly in focus. Objective: In this paper, we present a bibliometric review with the aim of contributing to a better understanding and clarification of concepts and terms associated with the area of Linked Data. Methodology: We have used the Web of Science (WoS, Scopus, EBSCO and IEEE scientific databases, in order to find the existing studies about Linked Data until October 2012. Results: We have mapped 148 scientific papers that address the above issue, written by 409 authors from 160 institutions from 30 different countries. Through the analysis of the articles, it was found that researches about Linked Data are concentrated in a small authors group, suggesting future research opportunities. Conclusions: Synthesizing the information related to the scientific publications in a given area allows building a theoretical background that supports the development of future researches.

  9. Nonlinear control techniques of a controllable rectifier/inverter-motor drive system with a small dc-link capacitor

    International Nuclear Information System (INIS)

    Liutanakul, Pisit; Pierfederici, Serge; Meibody-Tabar, Farid

    2008-01-01

    The necessity of the converters compactness in many applications imposes the reduction of their different components size when it is possible. In this paper, a control method allowing the use of a small size dc-link capacitor for the cascade of voltage controlled-rectifier/inverter-motor drive system is proposed. This is achieved by adding the power balance equation in the system's model and the application of an exact input/output feedback linearization technique in a way that the rectifier controller compensates any sudden change in the inverter load, which is here an induction motor. Since the exact input/output feedback linearization technique is sensitive to the uncertainties over system parameters, a robust control strategy based on sliding mode controller is proposed. By this approach, the dc-link voltage becomes almost insensitive to the load variations. As a result, the level of the dc-link voltage could be stabilized with a small size dc-link capacitor. Without any considerations of the RMS current stress on this dc-link capacitor, a calculation method of a minimum value of this capacitor based on its storage energy is proposed. All the investigations are shown by computer simulations and the performance of controlled system is verified by experimentation results

  10. Laboratory experiments of bucket foundations under cyclic loading

    DEFF Research Database (Denmark)

    Foglia, Aligi; Ibsen, Lars Bo

    This report collects information on the experimental campaign concerning bucket foundations under lateral cyclic loading conducted by the authors between 2011 and 2014. The report includes a step by step manual on the test procedures and a number of information and graphs for each experiment...

  11. Load research manual. Volume 1. Load research procedures

    Energy Technology Data Exchange (ETDEWEB)

    Brandenburg, L.; Clarkson, G.; Grund, Jr., C.; Leo, J.; Asbury, J.; Brandon-Brown, F.; Derderian, H.; Mueller, R.; Swaroop, R.

    1980-11-01

    This three-volume manual presents technical guidelines for electric utility load research. Special attention is given to issues raised by the load data reporting requirements of the Public Utility Regulatory Policies Act of 1978 and to problems faced by smaller utilities that are initiating load research programs. In Volumes 1 and 2, procedures are suggested for determining data requirements for load research, establishing the size and customer composition of a load survey sample, selecting and using equipment to record customer electricity usage, processing data tapes from the recording equipment, and analyzing the data. Statistical techniques used in customer sampling are discussed in detail. The costs of load research also are estimated, and ongoing load research programs at three utilities are described. The manual includes guides to load research literature and glossaries of load research and statistical terms.

  12. Chinese adolescents' reports of covert parental monitoring: Comparisons with overt monitoring and links with information management.

    Science.gov (United States)

    Hawk, Skyler T

    2017-02-01

    This study compared Chinese adolescents' reports of covert parental monitoring with the overt strategies of solicitation and control. We investigated these behaviors in terms of unique associations with adolescents' perceived privacy invasion and the information management behaviors of disclosure and secrecy. High school students (N = 455, 61.5% female; M age  = 17.39, SD = 0.83) from a predominantly rural province of Mainland China reported a high incidence of covert monitoring (60.40%). Covert monitoring predicted privacy invasion more strongly than solicitation or control. Solicitation positively predicted disclosure, while covert monitoring negatively predicted disclosure and positively predicted secrecy. Privacy invasion fully mediated links between covert monitoring and information management. These latter effects were significantly stronger for girls than for boys. Similar to Western adolescents, Chinese youth might apply selective resistance when parents violate their personal domain. The findings suggest linkage between some parental monitoring behaviors and disruptions in Chinese family communication. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  13. Accommodating Oversize and Overweight Loads : Instructor and Student Guide

    Science.gov (United States)

    2012-08-01

    This instructor and student guide is designed to guide the instructor in conveying information at the district level concerning Research Project 0-6404 Accommodating Oversize and Overweight Loads. The specific information focuses on the Bryan D...

  14. Linking Data and Publications: Towards a Cross-Disciplinary Approach

    Directory of Open Access Journals (Sweden)

    Maarten Hoogerwerf

    2013-06-01

    Full Text Available In this paper, we tackle the challenge of linking scholarly information in multi-disciplinary research infrastructures. There is a trend towards linking publications with research data and other information, but, as it is still emerging, this is handled differently by various initiatives and disciplines. For OpenAIRE, a European cross-disciplinary publication infrastructure, this poses the challenge of supporting these heterogeneous practices. Hence, OpenAIRE wants to contribute to the development of a common approach for discipline-independent linking practices between publications, data, project information and researchers. To this end, we constructed two demonstrators to identify commonalities and differences. The results show the importance of stable and unique identifiers, and support a ‘by reference’ approach of interlinking research results. This approach allows discipline-specific research information to be managed independently in distributed systems and avoids redundant maintenance. Furthermore, it allows these disciplinary systems to manage the specialized structures of their contents themselves.

  15. I can see clearly now: the effects of age and perceptual load on inattentional blindness.

    Science.gov (United States)

    Remington, Anna; Cartwright-Finch, Ula; Lavie, Nilli

    2014-01-01

    Attention and awareness are known to be linked (e.g., see Lavie et al., 2014, for a review). However the extent to which this link changes over development is not fully understood. Most research concerning the development of attention has investigated the effects of attention on distraction, visual search and spatial orienting, typically using reaction time measures which cannot directly support conclusions about conscious awareness. Here we used Lavie's Load Theory of Attention and Cognitive Control to examine the development of attention effects on awareness. According to Load Theory, awareness levels are determined by the availability of attentional capacity. We hypothesized that attentional capacity develops with age, and consequently that awareness rates should increase with development due to the enhanced capacity. Thus we predicted that greater rates of inattentional blindness (IB) would be found at a younger age, and that lower levels of load will be sufficient to exhaust capacity and cause IB in children but not adults. We tested this hypothesis using an IB paradigm with adults and children aged 7-8, 9-10, 11-12 and 13 years old. Participants performed a line-length judgment task (indicating which arm of a cross is longer) and on the last trial were asked to report whether they noticed an unexpected task-irrelevant stimulus (a small square) in the display. Perceptual load was varied by changing the line-length difference (with a smaller difference in the conditions of higher load). The results supported our hypothesis: levels of awareness increased with age, and a moderate increase in the perceptual load of the task led to greater IB for children but not adults. These results extended across both peripheral and central presentations of the task stimuli. Overall, these findings establish the development of capacity for awareness and demonstrate the critical role of the perceptual load in the attended task.

  16. I can see clearly now: The effects of age and perceptual load on inattentional blindness

    Directory of Open Access Journals (Sweden)

    Anna eRemington

    2014-04-01

    Full Text Available Attention and awareness are known to be linked (e.g. see Lavie, Beck, & Konstantinou, 2014, for a review. However the extent to which this link changes over development is not fully understood. Most research concerning the development of attention has investigated the effects of attention on distraction, visual search and spatial orienting, typically using reaction time measures which cannot directly support conclusions about conscious awareness. Here we used Lavie’s Load Theory of Attention and Cognitive Control to examine the development of attention effects on awareness. According to Load Theory awareness levels are determined by the availability of attentional capacity. We hypothesised that attentional capacity develops with age, and consequently that awareness rates should increase with development due to the enhanced capacity. Thus we predicted that greater rates of inattentional blindness (IB would be found at a younger age, and that lower levels of perceptual load will be sufficient to exhaust capacity and cause IB in children but not adults. We tested this hypothesis using an IB paradigm with adults and children aged 7-8, 9-10, 11-12 and 13 years old. Participants performed a line-length judgment task (indicating which arm of a cross is longer and on the last trial were asked to report whether they noticed an unexpected task-irrelevant stimulus (a small square in the display. Perceptual load was varied by changing the line-length difference (with a smaller difference in the conditions of higher load. The results supported our hypothesis: levels of awareness increased with age, and a moderate increase in the perceptual load of the task led to greater IB for children but not adults. These results extended across both peripheral and central presentations of the task stimuli. Overall, these findings establish the development of capacity for awareness and demonstrate the critical role of the perceptual load in the attended task.

  17. Using Perspective to Resolve Reference: The Impact of Cognitive Load and Motivation

    Science.gov (United States)

    Cane, James E.; Ferguson, Heather J.; Apperly, Ian A.

    2017-01-01

    Research has demonstrated a link between perspective taking and working memory. Here we used eye tracking to examine the time course with which working memory load (WML) influences perspective-taking ability in a referential communication task and how motivation to take another's perspective modulates these effects. In Experiment 1, where there…

  18. 1993 Pacific Northwest Loads and Resources Study, Technical Appendix: Volume 2, Book 1, Energy.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1993-12-01

    The 1993 Pacific Northwest Loads and Resources Study establishes the Bonneville Power Administration`s (BPA) planning basis for supplying electricity to BPA customers. The Loads and Resources Study is presented in three documents: (1) this technical appendix detailing loads and resources for each major Pacific and Northwest generating utility, (2) a summary of Federal system and Pacific Northwest region loads and resources, and (3) a technical appendix detailing forecasted Pacific Northwest economic trends and loads. This analysis updates the 1992 Pacific Northwest Loads and Resources Study Technical Appendix published in December 1992. This technical appendix provides utility-specific information that BPA uses in its long-range planning. It incorporates the following for each utility (1) Electrical demand firm loads; (2) Generating resources; and (3) Contracts both inside and outside the region. This document should be used in combination with the 1993 Pacific Northwest Loads and Resources Study, published in December 1993, because much of the information in that document is not duplicated here.

  19. Load power device, system and method of load control and management employing load identification

    Science.gov (United States)

    Yang, Yi; Luebke, Charles John; Schoepf, Thomas J.

    2018-01-09

    A load power device includes a power input, at least one power output for at least one load, a plurality of sensors structured to sense voltage and current at the at least one power output, and a processor. The processor provides: (a) load identification based upon the sensed voltage and current, and (b) load control and management based upon the load identification.

  20. Daily Air Temperature and Electricity Load in Spain.

    Science.gov (United States)

    Valor, Enric; Meneu, Vicente; Caselles, Vicente

    2001-08-01

    Weather has a significant impact on different sectors of the economy. One of the most sensitive is the electricity market, because power demand is linked to several weather variables, mainly the air temperature. This work analyzes the relationship between electricity load and daily air temperature in Spain, using a population-weighted temperature index. The electricity demand shows a significant trend due to socioeconomic factors, in addition to daily and monthly seasonal effects that have been taken into account to isolate the weather influence on electricity load. The results indicate that the relationship is nonlinear, showing a `comfort interval' of ±3°C around 18°C and two saturation points beyond which the electricity load no longer increases. The analysis has also revealed that the sensitivity of electricity load to daily air temperature has increased along time, in a higher degree for summer than for winter, although the sensitivity in the cold season is always more significant than in the warm season. Two different temperature-derived variables that allow a better characterization of the observed relationship have been used: the heating and cooling degree-days. The regression of electricity data on them defines the heating and cooling demand functions, which show correlation coefficients of 0.79 and 0.87, and predicts electricity load with standard errors of estimate of ±4% and ±2%, respectively. The maximum elasticity of electricity demand is observed at 7 cooling degree-days and 9 heating degree-days, and the saturation points are reached at 11 cooling degree-days and 13 heating degree-days, respectively. These results are helpful in modeling electricity load behavior for predictive purposes.

  1. Preanalytic process linked to spuriously elevated HIV viral loads: improvement on an FDA-approved process.

    Science.gov (United States)

    Procop, Gary W; Taege, Alan J; Starkey, Colleen; Tungsiripat, Marisa; Warner, Diane; Schold, Jesse D; Yen-Lieberman, Belinda

    2017-09-01

    The processing of specimens often occurs in a central processing area within laboratories. We demonstrated that plasma centrifuged in the central laboratory but allowed to remain within the primary tube following centrifugation was associated with spuriously elevated HIV viral loads compared with recentrifugation of the plasma just prior to testing. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Fuzzy approach for short term load forecasting

    Energy Technology Data Exchange (ETDEWEB)

    Chenthur Pandian, S.; Duraiswamy, K.; Kanagaraj, N. [Electrical and Electronics Engg., K.S. Rangasamy College of Technology, Tiruchengode 637209, Tamil Nadu (India); Christober Asir Rajan, C. [Department of Electrical and Electronics Engineering, Pondicherry Engineering College, Pondicherry (India)

    2006-04-15

    The main objective of short term load forecasting (STLF) is to provide load predictions for generation scheduling, economic load dispatch and security assessment at any time. The STLF is needed to supply necessary information for the system management of day-to-day operations and unit commitment. In this paper, the 'time' and 'temperature' of the day are taken as inputs for the fuzzy logic controller and the 'forecasted load' is the output. The input variable 'time' has been divided into eight triangular membership functions. The membership functions are Mid Night, Dawn, Morning, Fore Noon, After Noon, Evening, Dusk and Night. Another input variable 'temperature' has been divided into four triangular membership functions. They are Below Normal, Normal, Above Normal and High. The 'forecasted load' as output has been divided into eight triangular membership functions. They are Very Low, Low, Sub Normal, Moderate Normal, Normal, Above Normal, High and Very High. Case studies have been carried out for the Neyveli Thermal Power Station Unit-II (NTPS-II) in India. The fuzzy forecasted load values are compared with the conventional forecasted values. The forecasted load closely matches the actual one within +/-3%. (author)

  3. Dual Cross-Linked Carboxymethyl Sago Pulp-Gelatine Complex Coacervates for Sustained Drug Delivery

    Directory of Open Access Journals (Sweden)

    Saravanan Muniyandy

    2015-06-01

    Full Text Available In the present work, we report for the first time the complex coacervation of carboxymethyl sago pulp (CMSP with gelatine for sustained drug delivery. Toluene saturated with glutaraldehyde and aqueous aluminum chloride was employed as cross-linkers. Measurements of zeta potential confirm neutralization of two oppositely charged colloids due to complexation, which was further supported by infrared spectroscopy. The coacervates encapsulated a model drug ibuprofen and formed microcapsules with a loading of 29%–56% w/w and an entrapment efficiency of 85%–93% w/w. Fresh coacervates loaded with drug had an average diameter of 10.8 ± 1.93 µm (n = 3 ± s.d.. The coacervates could encapsulate only the micronized form of ibuprofen in the absence of surfactant. Analysis through an optical microscope evidenced the encapsulation of the drug in wet spherical coacervates. Scanning electron microscopy revealed the non-spherical geometry and surface roughness of dried drug-loaded microcapsules. X-ray diffraction, differential scanning calorimetry and thermal analysis confirmed intact and crystalline ibuprofen in the coacervates. Gas chromatography indicated the absence of residual glutaraldehyde in the microcapsules. Dual cross-linked microcapsules exhibited a slower release than mono-cross-linked microcapsules and could sustain the drug release over the period of 6 h following Fickian diffusion.

  4. Tapping the energy storage potential in electric loads to deliver load following and regulation, with application to wind energy

    International Nuclear Information System (INIS)

    Callaway, Duncan S.

    2009-01-01

    This paper develops new methods to model and control the aggregated power demand from a population of thermostatically controlled loads, with the goal of delivering services such as regulation and load following. Previous work on direct load control focuses primarily on peak load shaving by directly interrupting power to loads. In contrast, the emphasis of this paper is on controlling loads to produce relatively short time scale responses (hourly to sub-hourly), and the control signal is applied by manipulation of temperature set points, possibly via programmable communicating thermostats or advanced metering infrastructure. To this end, the methods developed here leverage the existence of system diversity and use physically-based load models to inform the development of a new theoretical model that accurately predicts - even when the system is not in equilibrium - changes in load resulting from changes in thermostat temperature set points. Insight into the transient dynamics that result from set point changes is developed by deriving a new exact solution to a well-known hybrid state aggregated load model. The eigenvalues of the solution, which depend only on the thermal time constant of the loads under control, are shown to have a strong effect on the accuracy of the model. The paper also shows that load heterogeneity - generally something that must be assumed away in direct load control models - actually has a positive effect on model accuracy. System identification techniques are brought to bear on the problem, and it is shown that identified models perform only marginally better than the theoretical model. The paper concludes by deriving a minimum variance control law, and demonstrates its effectiveness in simulations wherein a population of loads is made to follow the output of a wind plant with very small changes in the nominal thermostat temperature set points.

  5. Occlusal loading and cross-linking effects on dentin collagen degradation in physiological conditions.

    Science.gov (United States)

    Turco, Gianluca; Frassetto, Andrea; Fontanive, Luca; Mazzoni, Annalisa; Cadenaro, Milena; Di Lenarda, Roberto; Tay, Franklin R; Pashley, David H; Breschi, Lorenzo

    2016-02-01

    This study evaluated the ability of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride (EDC) to improve the stability of demineralized dentin collagen matrices when subjected to mechanical cycling by means of Chewing Simulation (CS). Demineralized dentin disks were randomly assigned to four groups (N=4): (1) immersion in artificial saliva at 37°C for 30 days; (2) pre-treatment with 0.5 M EDC for 60 s, then stored as in Group 1; (3) CS challenge (50 N occlusal load, 30 s occlusal time plus 30 s with no load, for 30 days); (4) pre-treatment with 0.5 M EDC as in Group 2 and CS challenge as in Group 3. Collagen degradation was evaluated by sampling storage media for ICTP and CTX telopeptides. EDC treated specimens showed no significant telopeptides release, irrespective of the aging method. Cyclic stressing of EDC-untreated specimens caused significantly higher ICTP release at day 1, compared to static storage, while by days 3 and 4, the ICTP release in the cyclic group fell significantly below the static group, and then remained undetectable from 5 to 30 days. CTX release in the cyclic groups, on EDC-untreated control specimens was always lower than in the static group in days 1-4, and then fell to undetectable for 30 days. This study showed that chewing stresses applied to control untreated demineralized dentin increased degradation of collagen in terms of CTX release, while collagen crosslinking agents may prevent dentin collagen degradation, irrespective of simulated occlusal function. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  6. Artificial Neural Networks for SCADA Data based Load Reconstruction (poster)

    NARCIS (Netherlands)

    Hofemann, C.; Van Bussel, G.J.W.; Veldkamp, H.

    2011-01-01

    If at least one reference wind turbine is available, which provides sufficient information about the wind turbine loads, the loads acting on the neighbouring wind turbines can be predicted via an artificial neural network (ANN). This research explores the possibilities to apply such a network not

  7. Maintenance of equilibrium point control during an unexpectedly loaded rapid limb movement.

    Science.gov (United States)

    Simmons, R W; Richardson, C

    1984-06-08

    Two experiments investigated whether the equilibrium point hypothesis or the mass-spring model of motor control subserves positioning accuracy during spring loaded, rapid, bi-articulated movement. For intact preparations, the equilibrium point hypothesis predicts response accuracy to be determined by a mixture of afferent and efferent information, whereas the mass-spring model predicts positioning to be under a direct control system. Subjects completed a series of load-resisted training trials to a spatial target. The magnitude of a sustained spring load was unexpectedly increased on selected trials. Results indicated positioning accuracy and applied force varied with increases in load, which suggests that the original efferent commands are modified by afferent information during the movement as predicted by the equilibrium point hypothesis.

  8. LINKING STATE, UNIVERSITY AND BUSINESS IN NICARAGUA

    Directory of Open Access Journals (Sweden)

    Máximo Andrés Rodríguez Pérez

    2015-07-01

    Full Text Available In Nicaragua levels Linking state, university and business are low, Nicaraguan universities have initiated communication strategies with the state and the private sector. The idiosyncrasies of its citizens favor this link. The entailment policies formalize the communications and information networks. Universities have a key role in building models and organizations that provide alternatives to economic development. Linking the university with the environment, generating virtuous circles, where companies achieve greater competitiveness, the state, higher taxes and public stability, universities generate new knowledge. This article analyzes the strategies linking U-E- E that can be applied in Nicaragua, to strengthen and achieve positive developments in the country.

  9. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... the main factors in the spread of HIV infection in the United States. Drugs can change the ... about the link between drug misuse and HIV infection. It contains information for young people, parents and ...

  10. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... It contains information for young people, parents and teachers, and the media with links to our latest ... greater injury to cells in the brain and cognitive impairment among people who use methamphetamine than among ...

  11. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... works, disrupting the parts of the brain that people use to weigh risks and benefits when making ... and HIV infection. It contains information for young people, parents and teachers, and the media with links ...

  12. Multimodal Information Presentation for High-Load Human Computer Interaction

    NARCIS (Netherlands)

    Cao, Y.

    2011-01-01

    This dissertation addresses multimodal information presentation in human computer interaction. Information presentation refers to the manner in which computer systems/interfaces present information to human users. More specifically, the focus of our work is not on which information to present, but

  13. Developing and Implementing an Assessment Technique to Measure Linked Concepts

    Science.gov (United States)

    Ye, Li; Oueini, Razanne; Lewis, Scott E.

    2015-01-01

    The links students make among chemistry content is considered essential for a robust, enduring understanding in multiple learning theories. This article describes the development and implementation of an assessment technique, termed a Measure of Linked Concepts, designed to inform instructors on students' understanding of linking content…

  14. A General Method for Targeted Quantitative Cross-Linking Mass Spectrometry.

    Directory of Open Access Journals (Sweden)

    Juan D Chavez

    Full Text Available Chemical cross-linking mass spectrometry (XL-MS provides protein structural information by identifying covalently linked proximal amino acid residues on protein surfaces. The information gained by this technique is complementary to other structural biology methods such as x-ray crystallography, NMR and cryo-electron microscopy[1]. The extension of traditional quantitative proteomics methods with chemical cross-linking can provide information on the structural dynamics of protein structures and protein complexes. The identification and quantitation of cross-linked peptides remains challenging for the general community, requiring specialized expertise ultimately limiting more widespread adoption of the technique. We describe a general method for targeted quantitative mass spectrometric analysis of cross-linked peptide pairs. We report the adaptation of the widely used, open source software package Skyline, for the analysis of quantitative XL-MS data as a means for data analysis and sharing of methods. We demonstrate the utility and robustness of the method with a cross-laboratory study and present data that is supported by and validates previously published data on quantified cross-linked peptide pairs. This advance provides an easy to use resource so that any lab with access to a LC-MS system capable of performing targeted quantitative analysis can quickly and accurately measure dynamic changes in protein structure and protein interactions.

  15. Validation of non-formal and informal learning from a European perspective – linking validation arrangements with national qualifications frameworks

    Directory of Open Access Journals (Sweden)

    Borut Mikulec

    2015-12-01

    Full Text Available The paper analyses European policy on the validation of non-formal and informal learning, which is presented as a “salvation narrative” that can improve the functioning of the labour market, provide a way out from unemployment and strengthen the competitiveness of the economy. Taking as our starting point recent findings in adult education theory on the validation of non-formal and informal learning, we aim to prove the thesis that what European validation policy promotes is above all economic purpose and that it establishes a “Credential/Credit-exchange” model of validation of non-formal and informal learning. We proceed to ecxamine the effect of European VNIL policy in selected European countries where validation arrangements are linked to the qualifications framework. We find that the “Credential/ Credit-exchange” validation model was first established in a few individual European countries and then transferred, as a “successful” model, to the level of common European VNIL policy.

  16. Development and Validation of Two Instruments Measuring Intrinsic, Extraneous, and Germane Cognitive Load

    Science.gov (United States)

    Klepsch, Melina; Schmitz, Florian; Seufert, Tina

    2017-01-01

    Cognitive Load Theory is one of the most powerful research frameworks in educational research. Beside theoretical discussions about the conceptual parts of cognitive load, the main challenge within this framework is that there is still no measurement instrument for the different aspects of cognitive load, namely intrinsic, extraneous, and germane cognitive load. Hence, the goal of this paper is to develop a differentiated measurement of cognitive load. In Study 1 (N = 97), we developed and analyzed two strategies to measure cognitive load in a differentiated way: (1) Informed rating: We trained learners in differentiating the concepts of cognitive load, so that they could rate them in an informed way. They were asked then to rate 24 different learning situations or learning materials related to either high or low intrinsic, extraneous, or germane load. (2) Naïve rating: For this type of rating of cognitive load we developed a questionnaire with two to three items for each type of load. With this questionnaire, the same learning situations had to be rated. In the second study (N = between 65 and 95 for each task), we improved the instrument for the naïve rating. For each study, we analyzed whether the instruments are reliable and valid, for Study 1, we also checked for comparability of the two measurement strategies. In Study 2, we conducted a simultaneous scenario based factor analysis. The informed rating seems to be a promising strategy to assess the different aspects of cognitive load, but it seems not economic and feasible for larger studies and a standardized training would be necessary. The improved version of the naïve rating turned out to be a useful, feasible, and reliable instrument. Ongoing studies analyze the conceptual validity of this measurement with up to now promising results. PMID:29201011

  17. Development and Validation of Two Instruments Measuring Intrinsic, Extraneous, and Germane Cognitive Load.

    Science.gov (United States)

    Klepsch, Melina; Schmitz, Florian; Seufert, Tina

    2017-01-01

    Cognitive Load Theory is one of the most powerful research frameworks in educational research. Beside theoretical discussions about the conceptual parts of cognitive load, the main challenge within this framework is that there is still no measurement instrument for the different aspects of cognitive load, namely intrinsic, extraneous, and germane cognitive load. Hence, the goal of this paper is to develop a differentiated measurement of cognitive load. In Study 1 ( N = 97), we developed and analyzed two strategies to measure cognitive load in a differentiated way: (1) Informed rating: We trained learners in differentiating the concepts of cognitive load, so that they could rate them in an informed way. They were asked then to rate 24 different learning situations or learning materials related to either high or low intrinsic, extraneous, or germane load. (2) Naïve rating: For this type of rating of cognitive load we developed a questionnaire with two to three items for each type of load. With this questionnaire, the same learning situations had to be rated. In the second study ( N = between 65 and 95 for each task), we improved the instrument for the naïve rating. For each study, we analyzed whether the instruments are reliable and valid, for Study 1, we also checked for comparability of the two measurement strategies. In Study 2, we conducted a simultaneous scenario based factor analysis. The informed rating seems to be a promising strategy to assess the different aspects of cognitive load, but it seems not economic and feasible for larger studies and a standardized training would be necessary. The improved version of the naïve rating turned out to be a useful, feasible, and reliable instrument. Ongoing studies analyze the conceptual validity of this measurement with up to now promising results.

  18. Development and Validation of Two Instruments Measuring Intrinsic, Extraneous, and Germane Cognitive Load

    Directory of Open Access Journals (Sweden)

    Melina Klepsch

    2017-11-01

    Full Text Available Cognitive Load Theory is one of the most powerful research frameworks in educational research. Beside theoretical discussions about the conceptual parts of cognitive load, the main challenge within this framework is that there is still no measurement instrument for the different aspects of cognitive load, namely intrinsic, extraneous, and germane cognitive load. Hence, the goal of this paper is to develop a differentiated measurement of cognitive load. In Study 1 (N = 97, we developed and analyzed two strategies to measure cognitive load in a differentiated way: (1 Informed rating: We trained learners in differentiating the concepts of cognitive load, so that they could rate them in an informed way. They were asked then to rate 24 different learning situations or learning materials related to either high or low intrinsic, extraneous, or germane load. (2 Naïve rating: For this type of rating of cognitive load we developed a questionnaire with two to three items for each type of load. With this questionnaire, the same learning situations had to be rated. In the second study (N = between 65 and 95 for each task, we improved the instrument for the naïve rating. For each study, we analyzed whether the instruments are reliable and valid, for Study 1, we also checked for comparability of the two measurement strategies. In Study 2, we conducted a simultaneous scenario based factor analysis. The informed rating seems to be a promising strategy to assess the different aspects of cognitive load, but it seems not economic and feasible for larger studies and a standardized training would be necessary. The improved version of the naïve rating turned out to be a useful, feasible, and reliable instrument. Ongoing studies analyze the conceptual validity of this measurement with up to now promising results.

  19. Combined Rate and Power Allocation with Link Scheduling in Wireless Data Packet Relay Networks with Fading Channels

    Directory of Open Access Journals (Sweden)

    Subhrakanti Dey

    2007-08-01

    Full Text Available We consider a joint rate and power control problem in a wireless data traffic relay network with fading channels. The optimization problem is formulated in terms of power and rate selection, and link transmission scheduling. The objective is to seek high aggregate utility of the relay node when taking into account buffer load management and power constraints. The optimal solution for a single transmitting source is computed by a two-layer dynamic programming algorithm which leads to optimal power, rate, and transmission time allocation at the wireless links. We further consider an optimal power allocation problem for multiple transmitting sources in the same framework. Performances of the resource allocation algorithms including the effect of buffer load control are illustrated via extensive simulation studies.

  20. Effect of electron beam-cross-linked gels on the rheological properties of raw natural rubber

    Energy Technology Data Exchange (ETDEWEB)

    Mitra, Suman; Chattopadhyay, Santanu [Rubber Technology Centre, Indian Institute of Technology, Kharagpur, West Bengal 721302 (India); Bharadwaj, Y.K.; Sabharwal, S. [Radiation Technology Development Section, Bhabha Atomic Research Center, Trombay, Mumbai 400085 (India); Bhowmick, Anil K. [Rubber Technology Centre, Indian Institute of Technology, Kharagpur, West Bengal 721302 (India)], E-mail: anilkb@rtc.iitkgp.ernet.in

    2008-05-15

    Electron beam (EB)-cross-linked natural rubber (NR) gels were prepared from latex and characterized by various techniques. The addition of a small amount of these gels to raw NR was found to reduce the apparent shear viscosity and die swell remarkably. This effect was further enhanced with the addition of butyl acrylate as a sensitizer. The apparent shear viscosity first decreased up to 8 phr of gel loading and then increased. However, the percent die swell value decreased steadily upon gel loading. These were explained by calculating principal normal stress difference, the activation energy of melt flow and characteristics of EB-cross-linked gels. These effects were also reflected in the changes of mechanical and dynamic mechanical properties of gel-filled raw NR. Tailoring of the above properties could be done with the help of these gels.

  1. The NIF LinkOut broker: a web resource to facilitate federated data integration using NCBI identifiers.

    Science.gov (United States)

    Marenco, Luis; Ascoli, Giorgio A; Martone, Maryann E; Shepherd, Gordon M; Miller, Perry L

    2008-09-01

    This paper describes the NIF LinkOut Broker (NLB) that has been built as part of the Neuroscience Information Framework (NIF) project. The NLB is designed to coordinate the assembly of links to neuroscience information items (e.g., experimental data, knowledge bases, and software tools) that are (1) accessible via the Web, and (2) related to entries in the National Center for Biotechnology Information's (NCBI's) Entrez system. The NLB collects these links from each resource and passes them to the NCBI which incorporates them into its Entrez LinkOut service. In this way, an Entrez user looking at a specific Entrez entry can LinkOut directly to related neuroscience information. The information stored in the NLB can also be utilized in other ways. A second approach, which is operational on a pilot basis, is for the NLB Web server to create dynamically its own Web page of LinkOut links for each NCBI identifier in the NLB database. This approach can allow other resources (in addition to the NCBI Entrez) to LinkOut to related neuroscience information. The paper describes the current NLB system and discusses certain design issues that arose during its implementation.

  2. Commentary: Should Gender Differences Be Included in the Evolutionary Upgrade to Cognitive Load Theory?

    Science.gov (United States)

    Bevilacqua, Andy

    2017-01-01

    Recent upgrades to cognitive load theory suggest that evolutionary processes have shaped the way that working memory processes cultural and social information. According to evolutionarily educational psychologists, some forms of information are processed with lower working memory loads than other forms. The former are evolutionarily salient and…

  3. A network flow model for load balancing in circuit-switched multicomputers

    Science.gov (United States)

    Bokhari, Shahid H.

    1990-01-01

    In multicomputers that utilize circuit switching or wormhole routing, communication overhead depends largely on link contention - the variation due to distance between nodes is negligible. This has a major impact on the load balancing problem. In this case, there are some nodes with excess load (sources) and others with deficit load (sinks) and it is required to find a matching of sources to sinks that avoids contention. The problem is made complex by the hardwired routing on currently available machines: the user can control only which nodes communicate but not how the messages are routed. Network flow models of message flow in the mesh and the hypercube were developed to solve this problem. The crucial property of these models is the correspondence between minimum cost flows and correctly routed messages. To solve a given load balancing problem, a minimum cost flow algorithm is applied to the network. This permits one to determine efficiently a maximum contention free matching of sources to sinks which, in turn, tells one how much of the given imbalance can be eliminated without contention.

  4. The effects of combining dynamic pricing, AC load control, and real-time energy feedback. SMUD'S 2011 Residential Summer Solutions Study

    Energy Technology Data Exchange (ETDEWEB)

    Herter, K. [Herter Energy Research Solutions, El Dorado Hills, CA (United States); Wood, V. [Sacramento Municipal Utility District, Sacramento, CA (United States); Blozis, S. [University of California, Davis, CA (United States)

    2013-11-15

    The 2011 Residential Summer Solutions Study compared the hourly load effects of three different real-time information treatments and two program options. The information treatments included: Baseline information (no real-time data), real-time Home information (whole-house data), and real-time Appliance information (data for the whole house plus three individual appliances). Compared to the Baseline group, real-time Home information lowered overall energy use by about 4 %. Real-time information at both the Home and Appliance levels had a significant effect on non-event peak loads: compared to the Baseline group, real-time Home data lowered peak load by 5 %, while Appliance data lowered peak load by 7 %. All three information treatments averaged a 1-kW (40 %) load shed during events. The customer-chosen program options included a dynamic time-of-use rate and a load control incentive program. Customers were more likely to sign up for the dynamic rate, and those who did saved significantly more peak load on both event days (>50 % savings) and non-event days (>20 % savings) than did those on the load control program alone. In addition, those on the dynamic rate saved twice as much on their summer bills as did those who chose to remain on the standard tiered rate. At the end of the summer, more than 90 % of participants signed up to participate again the following year.

  5. Real Time Monitoring and Supervisory Control of Distribution Load Based on Generic Load Allocation: A Smart Grid Solution

    Directory of Open Access Journals (Sweden)

    Anwer Ahmed Memon

    2014-04-01

    Full Text Available Our work is the small part of the smart grid system. This is regarding the check and balance of power consumption at the consumer level. It is a well known fact that the consumers are allocated a fixed load according to their requirement at the time of application for the electricity connection. When the consumer increases its load and does not inform the power company, the result is the overloading of the system. This paper presents a solution regarding distribution and load allocation to each customer. If the customer uses power greater than the load allocated, further power is not provided and consequently that appliance is not turned on unless the total load must not be decreased than the allocated load. This is achieved by designing a processor controlled system that measures the power on main line and also the power taken by each device. Now when a device is turned on, its power is measured by the controller and compares it with the main line power, and when the device consumes some power consequently main line power will also be increased thus this main line power is monitored and if it exceeds particular limit that device is turned off through its relay

  6. Real time monitoring and supervisory control of distribution load based on generic load allocation: a smart grid solution

    International Nuclear Information System (INIS)

    Memon, A.W.; Memon, Z.A.; Aamir, R.R.

    2014-01-01

    Our work is the small part of the smart grid system. This is regarding the check and balance of power consumption at the consumer level. It is a well known fact that the consumers are allocated a fixed load according to their requirement at the time of application for the electricity connection. When the consumer increases its load and does not inform the power company, the result is the overloading of the system. This paper presents a solution regarding distribution and load allocation to each customer. If the customer uses power greater than the load allocated, further power is not provided and consequently that appliance is not turned on unless the total load must not be decreased than the allocated load. This is achieved by designing a processor controlled system that measures the power on main line and also the power taken by each device. Now when a device is turned on, its power is measured by the controller and compares it with the main line power, and when the device consumes some power consequently main line power will also be increased thus this main line power is monitored and if it exceeds particular limit that device is turned off through its relay. (author)

  7. Linked Data Paves the Way to Improved Health Care

    Directory of Open Access Journals (Sweden)

    Michael Gaucher

    2017-04-01

    This presentation demonstrates how new knowledge created using linked data can inform decision and policy makers, and lead to action within the health system. Several examples are presented to illustrate the approach and types of data being linked.

  8. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... En español Researchers Medical & Health Professionals Patients & Families Parents & Educators Children & Teens Search Connect with NIDA : Facebook ... HIV infection. It contains information for young people, parents and teachers, and the media with links to ...

  9. Fifth Baltic Sea pollution load compilation (PLC-5). An executive summary

    Energy Technology Data Exchange (ETDEWEB)

    Svendsen, L.M.; Staaf, H.; Pyhala, M.; Kotilainen, P.; Bartnicki, J.; Knuuttila, S.; Durkin, M.

    2012-07-01

    This report summarizes and combines the main results of the Fifth Baltic Sea Pollution Load Compilation (HELCOM 2011) which covers waterborne loads to the sea and data on atmospheric loads which are submitted by countries to the co-operative programme for monitoring and evaluation of the long range transmission of air pollutants in Europe (EMEP), which subsequently compiles and reports this information to HELCOM.

  10. Additional helmet and pack loading reduce situational awareness during the establishment of marksmanship posture.

    Science.gov (United States)

    Lim, Jongil; Palmer, Christopher J; Busa, Michael A; Amado, Avelino; Rosado, Luis D; Ducharme, Scott W; Simon, Darnell; Van Emmerik, Richard E A

    2017-06-01

    The pickup of visual information is critical for controlling movement and maintaining situational awareness in dangerous situations. Altered coordination while wearing protective equipment may impact the likelihood of injury or death. This investigation examined the consequences of load magnitude and distribution on situational awareness, segmental coordination and head gaze in several protective equipment ensembles. Twelve soldiers stepped down onto force plates and were instructed to quickly and accurately identify visual information while establishing marksmanship posture in protective equipment. Time to discriminate visual information was extended when additional pack and helmet loads were added, with the small increase in helmet load having the largest effect. Greater head-leading and in-phase trunk-head coordination were found with lighter pack loads, while trunk-leading coordination increased and head gaze dynamics were more disrupted in heavier pack loads. Additional armour load in the vest had no consequences for Time to discriminate, coordination or head dynamics. This suggests that the addition of head borne load be carefully considered when integrating new technology and that up-armouring does not necessarily have negative consequences for marksmanship performance. Practitioner Summary: Understanding the trade-space between protection and reductions in task performance continue to challenge those developing personal protective equipment. These methods provide an approach that can help optimise equipment design and loading techniques by quantifying changes in task performance and the emergent coordination dynamics that underlie that performance.

  11. Investigation programme and procedure for creep and long-term rupture strength in materials with accounting for stress deviator and loading history

    International Nuclear Information System (INIS)

    Mozharovskaya, T.N.

    1984-01-01

    A programme and procedure are given to study 08Kh18N9 steel at 600 deg C and 15Kh2MFA steel at 550 deg C for creep and long-term strength at different parameters of proportional loading as well as at different parameters under loading in two-link irregular trajectories. This makes it possible to estimate the effect of the kind of a stress deviator, history and prehistory of loading on plastic deformation in creep and on failure under long-term loading

  12. Investigation programme and procedure for creep and long-term rupture strength in materials with accounting for stress deviator and loading history

    Energy Technology Data Exchange (ETDEWEB)

    Mozharovskaya, T N [AN Ukrainskoj SSR, Kiev. Inst. Problem Prochnosti

    1984-11-01

    A programme and procedure are given to study 08Kh18N9 steel at 600 deg C and 15Kh2MFA steel at 550 deg C for creep and long-term strength at different parameters of proportional loading as well as at different parameters under loading in two-link irregular trajectories. This makes it possible to estimate the effect of the kind of a stress deviator, history and prehistory of loading on plastic deformation in creep and on failure under long-term loading.

  13. An efficient link prediction index for complex military organization

    Science.gov (United States)

    Fan, Changjun; Liu, Zhong; Lu, Xin; Xiu, Baoxin; Chen, Qing

    2017-03-01

    Quality of information is crucial for decision-makers to judge the battlefield situations and design the best operation plans, however, real intelligence data are often incomplete and noisy, where missing links prediction methods and spurious links identification algorithms can be applied, if modeling the complex military organization as the complex network where nodes represent functional units and edges denote communication links. Traditional link prediction methods usually work well on homogeneous networks, but few for the heterogeneous ones. And the military network is a typical heterogeneous network, where there are different types of nodes and edges. In this paper, we proposed a combined link prediction index considering both the nodes' types effects and nodes' structural similarities, and demonstrated that it is remarkably superior to all the 25 existing similarity-based methods both in predicting missing links and identifying spurious links in a real military network data; we also investigated the algorithms' robustness under noisy environment, and found the mistaken information is more misleading than incomplete information in military areas, which is different from that in recommendation systems, and our method maintained the best performance under the condition of small noise. Since the real military network intelligence must be carefully checked at first due to its significance, and link prediction methods are just adopted to purify the network with the left latent noise, the method proposed here is applicable in real situations. In the end, as the FINC-E model, here used to describe the complex military organizations, is also suitable to many other social organizations, such as criminal networks, business organizations, etc., thus our method has its prospects in these areas for many tasks, like detecting the underground relationships between terrorists, predicting the potential business markets for decision-makers, and so on.

  14. Assessment of Industrial Load for Demand Response across Western Interconnect

    Energy Technology Data Exchange (ETDEWEB)

    Alkadi, Nasr E [ORNL; Starke, Michael R [ORNL; Ma, Ookie [United States Department of Energy (DOE), Office of Efficiency and Renewable Energy (EERE)

    2013-11-01

    Demand response (DR) has the ability to both increase power grid reliability and potentially reduce operating system costs. Understanding the role of demand response in grid modeling has been difficult due to complex nature of the load characteristics compared to the modeled generation and the variation in load types. This is particularly true of industrial loads, where hundreds of different industries exist with varying availability for demand response. We present a framework considering industrial loads for the development of availability profiles that can provide more regional understanding and can be inserted into analysis software for further study. The developed framework utilizes a number of different informational resources, algorithms, and real-world measurements to perform a bottom-up approach in the development of a new database with representation of the potential demand response resource in the industrial sector across the U.S. This tool houses statistical values of energy and demand response (DR) potential by industrial plant and geospatially locates the information for aggregation for different territories without proprietary information. This report will discuss this framework and the analyzed quantities of demand response for Western Interconnect (WI) in support of evaluation of the cost production modeling with power grid modeling efforts of demand response.

  15. Working memory and spatial judgments: Cognitive load increases the central tendency bias.

    Science.gov (United States)

    Allred, Sarah R; Crawford, L Elizabeth; Duffy, Sean; Smith, John

    2016-12-01

    Previous work demonstrates that memory for simple stimuli can be biased by information about the distribution of which the stimulus is a member. Specifically, people underestimate values greater than the distribution's average and overestimate values smaller than the average. This is referred to as the central tendency bias. This bias has been explained as an optimal use of both noisy sensory information and category information. In largely separate literature, cognitive load (CL) experiments attempt to manipulate the available working memory of participants in order to observe the effect on choice or judgments. In two experiments, we demonstrate that participants under high cognitive load exhibit a stronger central tendency bias than when under a low cognitive load. Although not anticipated at the outset, we also find that judgments exhibit an anchoring bias not described previously.

  16. Model of load balancing using reliable algorithm with multi-agent system

    Science.gov (United States)

    Afriansyah, M. F.; Somantri, M.; Riyadi, M. A.

    2017-04-01

    Massive technology development is linear with the growth of internet users which increase network traffic activity. It also increases load of the system. The usage of reliable algorithm and mobile agent in distributed load balancing is a viable solution to handle the load issue on a large-scale system. Mobile agent works to collect resource information and can migrate according to given task. We propose reliable load balancing algorithm using least time first byte (LFB) combined with information from the mobile agent. In system overview, the methodology consisted of defining identification system, specification requirements, network topology and design system infrastructure. The simulation method for simulated system was using 1800 request for 10 s from the user to the server and taking the data for analysis. Software simulation was based on Apache Jmeter by observing response time and reliability of each server and then compared it with existing method. Results of performed simulation show that the LFB method with mobile agent can perform load balancing with efficient systems to all backend server without bottleneck, low risk of server overload, and reliable.

  17. Synthesis and Characterization of Cleavable Core-Cross-Linked Micelles Based on Amphiphilic Block Copolypeptoids as Smart Drug Carriers.

    Science.gov (United States)

    Li, Ang; Zhang, Donghui

    2016-03-14

    Amphiphilic block copolypeptoids consisting of a hydrophilic poly(N-ethyl glycine) segment and a hydrophobic poly[(N-propargyl glycine)-r-(N-decyl glycine)] random copolymer segment [PNEG-b-P(NPgG-r-NDG), EPgD] have been synthesized by sequential primary amine-initiated ring-opening polymerization (ROP) of the corresponding N-alkyl N-carboxyanhydride monomers. The block copolypeptoids form micelles in water and the micellar core can be cross-linked with a disulfide-containing diazide cross-linker by copper-mediated alkyne-azide cycloaddition (CuAAC) in aqueous solution. Transmission electron microscopy (TEM) and dynamic light scattering (DLS) analysis revealed the formation of spherical micelles with uniform size for both the core-cross-linked micelles (CCLMs) and non-cross-linked micelles (NCLMs) precursors for selective block copolypeptoid polymers. The CCLMs exhibited increased dimensional stability relative to the NCLMs in DMF, a nonselective solvent for the core and corona segments. Micellar dissociation of CCLMs can be induced upon addition of a reducing agent (e.g., dithiothreitol) in dilute aqueous solutions, as verified by a combination of fluorescence spectroscopy, size exclusion chromatography (SEC), and (1)H NMR spectroscopic measurement. Doxorubicin (DOX), an anticancer drug, can be loaded into the hydrophobic core of CCLMs with a maximal 23% drug loading capacity (DLC) and 37% drug loading efficiency (DLE). In vitro DOX release from the CCLMs can be triggered by DTT (10 mM), in contrast to significantly reduced DOX release in the absence of DTT, attesting to the reductively responsive characteristic of the CCLMs. While the CCLMs exhibited minimal cytotoxicity toward HepG2 cancer cells, DOX-loaded CCLMs inhibited the proliferation of the HepG2 cancer cells in a concentration and time dependent manner, suggesting the controlled release of DOX from the DOX-loaded CCLMS in the cellular environment.

  18. Long-term forecasting of hourly electricity load: Identification of consumption profiles and segmentation of customers

    DEFF Research Database (Denmark)

    Møller Andersen, Frits; Larsen, Helge V.; Boomsma, Trine Krogh

    2013-01-01

    , to model and forecast long-term changes in the aggregated electricity load profile, we identify profiles for different categories of customers and link these to projections of the aggregated annual consumption by categories of customers. Long-term projection of the aggregated load is important for future......Data for aggregated hourly electricity demand shows systematic variations over the day, week, and seasons, and forecasting of aggregated hourly electricity load has been the subject of many studies. With hourly metering of individual customers, data for individual consumption profiles is available....... Using this data and analysing the case of Denmark, we show that consumption profiles for categories of customers are equally systematic but very different for distinct categories, that is, distinct categories of customers contribute differently to the aggregated electricity load profile. Therefore...

  19. Linked Ocean Data

    Science.gov (United States)

    Leadbetter, Adam; Arko, Robert; Chandler, Cynthia; Shepherd, Adam

    2014-05-01

    "Linked Data" is a term used in Computer Science to encapsulate a methodology for publishing data and metadata in a structured format so that links may be created and exploited between objects. Berners-Lee (2006) outlines the following four design principles of a Linked Data system: Use Uniform Resource Identifiers (URIs) as names for things. Use HyperText Transfer Protocol (HTTP) URIs so that people can look up those names. When someone looks up a URI, provide useful information, using the standards (Resource Description Framework [RDF] and the RDF query language [SPARQL]). Include links to other URIs so that they can discover more things. In 2010, Berners-Lee revisited his original design plan for Linked Data to encourage data owners along a path to "good Linked Data". This revision involved the creation of a five star rating system for Linked Data outlined below. One star: Available on the web (in any format). Two stars: Available as machine-readable structured data (e.g. An Excel spreadsheet instead of an image scan of a table). Three stars: As two stars plus the use of a non-proprietary format (e.g. Comma Separated Values instead of Excel). Four stars: As three stars plus the use of open standards from the World Wide Web Commission (W3C) (i.e. RDF and SPARQL) to identify things, so that people can point to your data and metadata. Five stars: All the above plus link your data to other people's data to provide context Here we present work building on the SeaDataNet common vocabularies served by the NERC Vocabulary Server, connecting projects such as the Rolling Deck to Repository (R2R) and the Biological and Chemical Oceanography Data Management Office (BCO-DMO) and other vocabularies such as the Marine Metadata Interoperability Ontology Register and Repository and the NASA Global Change Master Directory to create a Linked Ocean Data cloud. Publishing the vocabularies and metadata in standard RDF XML and exposing SPARQL endpoints renders them five-star Linked

  20. Link prediction in multiplex online social networks

    Science.gov (United States)

    Jalili, Mahdi; Orouskhani, Yasin; Asgari, Milad; Alipourfard, Nazanin; Perc, Matjaž

    2017-02-01

    Online social networks play a major role in modern societies, and they have shaped the way social relationships evolve. Link prediction in social networks has many potential applications such as recommending new items to users, friendship suggestion and discovering spurious connections. Many real social networks evolve the connections in multiple layers (e.g. multiple social networking platforms). In this article, we study the link prediction problem in multiplex networks. As an example, we consider a multiplex network of Twitter (as a microblogging service) and Foursquare (as a location-based social network). We consider social networks of the same users in these two platforms and develop a meta-path-based algorithm for predicting the links. The connectivity information of the two layers is used to predict the links in Foursquare network. Three classical classifiers (naive Bayes, support vector machines (SVM) and K-nearest neighbour) are used for the classification task. Although the networks are not highly correlated in the layers, our experiments show that including the cross-layer information significantly improves the prediction performance. The SVM classifier results in the best performance with an average accuracy of 89%.

  1. Software defined networks reactive flow programming and load balance switching

    OpenAIRE

    Καλλιανιώτης, Νικόλαος; Kallianiotis, Nikolaos

    2017-01-01

    This project serves as a Master Thesis as the requirements of the master’s programme Master of Digital Communications and Networks. It proposes load balancing algorithms applied to Software-Defined Networks to achieve the best possible resource utilisation of each of the links present in a network. The open-sources Opendaylight project and Floodlight project are used as SDN controllers, and the network is emulated using Mininet software

  2. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... AIDS : This site provides information both for health care providers and for Veterans and the public. Send the Message Overview Please help us send the message to young people and to parents, teachers, and the media about the link between ...

  3. Modelling self-optimised short term load forecasting for medium voltage loads using tunning fuzzy systems and Artificial Neural Networks

    International Nuclear Information System (INIS)

    Mahmoud, Thair S.; Habibi, Daryoush; Hassan, Mohammed Y.; Bass, Octavian

    2015-01-01

    Highlights: • A novel Short Term Medium Voltage (MV) Load Forecasting (STLF) model is presented. • A knowledge-based STLF error control mechanism is implemented. • An Artificial Neural Network (ANN)-based optimum tuning is applied on STLF. • The relationship between load profiles and operational conditions is analysed. - Abstract: This paper presents an intelligent mechanism for Short Term Load Forecasting (STLF) models, which allows self-adaptation with respect to the load operational conditions. Specifically, a knowledge-based FeedBack Tunning Fuzzy System (FBTFS) is proposed to instantaneously correlate the information about the demand profile and its operational conditions to make decisions for controlling the model’s forecasting error rate. To maintain minimum forecasting error under various operational scenarios, the FBTFS adaptation was optimised using a Multi-Layer Perceptron Artificial Neural Network (MLPANN), which was trained using Backpropagation algorithm, based on the information about the amount of error and the operational conditions at time of forecasting. For the sake of comparison and performance testing, this mechanism was added to the conventional forecasting methods, i.e. Nonlinear AutoRegressive eXogenous-Artificial Neural Network (NARXANN), Fuzzy Subtractive Clustering Method-based Adaptive Neuro Fuzzy Inference System (FSCMANFIS) and Gaussian-kernel Support Vector Machine (GSVM), and the measured forecasting error reduction average in a 12 month simulation period was 7.83%, 8.5% and 8.32% respectively. The 3.5 MW variable load profile of Edith Cowan University (ECU) in Joondalup, Australia, was used in the modelling and simulations of this model, and the data was provided by Western Power, the transmission and distribution company of the state of Western Australia.

  4. EDF studies on PWR vessel internal loading

    International Nuclear Information System (INIS)

    Bellet, S.; Vallat, S.

    1998-01-01

    EDF has undertaken some mechanics and thermal-hydraulics studies with the objective of mastering plant phenomena today and in order to numerically predict the behaviour of vessel internals on units planned for the future. From some justifications already underway after in operation incidents (wear and drop time of RCCA rods, fuel deflection, adapter cracks, baffle bolt cracks) we intend to control reactor vessel flows and mechanical behaviour of internal structures. During normal operation, thermal-hydraulic is the main load of vessel internals. The current approach consists of acquiring the capacity to link different calculations, taking care that codes are qualified for physical phenomena and complex 3D geometries. For baffle assembly, a more simple model of this structure has been used to treat the physical phenomena linked to the LOCA transient. Results are encouraging mainly due to code capacity progression (resolution and models), which allows more and more complex physical phenomena to be treated, like turbulence flow and LOCA. (author)

  5. PC-Link historical data base system MODCOMP/IBM at link for neutral particle beam operation

    International Nuclear Information System (INIS)

    Thurgood, P.

    1989-12-01

    ''PC-Link'' is a combination of hardware and software that connects an IBM PC/AT to a MODCOMP minicomputer. It is designed as an aid to the Neutral Beam operations coordinator during injection into the DIII-D tokamak project. An IBM PC/AT is linked to 4 MODCOMP ''realtime'' acquisition systems, each of which controls 2 neutral particle beam sources. At various points in the shot sequence, data is sent to the IBM PC/AT. This data can then be integrated with the data from the other sources into tables or graphics displays for use by the Beam Coordinator. In this way, the coordinator gets realtime feedback on the relative settings and performance of the sources and can observe trends within a particular source at one location. The PC- Link is used for observing relative timing information and for post shot historical archiving. The concept of the PC-Link was originally proposed several years ago. In April 1988, in-house implementation of the link software was begun. The PC-Link receives approximately 2 Kbytes of data per source per shot. This data is converted from MODCOMP format to IBM PC format and archived to disk. The last 280 shots per source are stored to disk to observe trends. The data can be displayed in a number of formats depending upon the situation. For example, prior to a shot, the beam MODCOMPs are sent timing information from the DIII-D tokamak control system. This data is echoed on the PC in a graphical representation displaying all 8 sources. At the end of the shot, the actual running times are displayed along with the requested settings. Any subset of the Historical data may be displayed either graphically or in tables for realtime comparisons between sources. This system is designed for realtime use, not for complete archiving purposes. This same data is also sent to a VAX computer for full integration into the archive database. This system is easily upgradable and extremely versatile. 4 figs

  6. Analisis Perbandingan Unjuk Kerja Sistem Penyeimbang Beban Web Server dengan HAProxy dan Pound Links

    Directory of Open Access Journals (Sweden)

    Dite Ardian

    2013-04-01

    Full Text Available The development of internet technology has many organizations that expanded service website. Initially used single web server that is accessible to everyone through the Internet, but when the number of users that access the web server is very much the traffic load to the web server and the web server anyway. It is necessary for the optimization of web servers to cope with the overload received by the web server when traffic is high. Methodology of this final project research include the study of literature, system design, and testing of the system. Methods from the literature reference books related as well as from several sources the internet. The design of this thesis uses Haproxy and Pound Links as a load balancing web server. The end of this reaserch is testing the network system, where the system will be tested this stage so as to create a web server system that is reliable and safe. The result is a web server system that can be accessed by many user simultaneously rapidly as load balancing Haproxy and Pound Links system which is set up as front-end web server performance so as to create a web server that has performance and high availability.

  7. Accelerated fatigue testing of dentin-composite bond with continuously increasing load.

    Science.gov (United States)

    Li, Kai; Guo, Jiawen; Li, Yuping; Heo, Young Cheul; Chen, Jihua; Xin, Haitao; Fok, Alex

    2017-06-01

    The aim of this study was to evaluate an accelerated fatigue test method that used a continuously increasing load for testing the dentin-composite bond strength. Dentin-composite disks (ϕ5mm×2mm) made from bovine incisor roots were subjected to cyclic diametral compression with a continuously increasingly load amplitude. Two different load profiles, linear and nonlinear with respect to the number of cycles, were considered. The data were then analyzed by using a probabilistic failure model based on the Weakest-Link Theory and the classical stress-life function, before being transformed to simulate clinical data of direct restorations. All the experimental data could be well fitted with a 2-parameter Weibull function. However, a calibration was required for the effective stress amplitude to account for the difference between static and cyclic loading. Good agreement was then obtained between theory and experiments for both load profiles. The in vitro model also successfully simulated the clinical data. The method presented will allow tooth-composite interfacial fatigue parameters to be determined more efficiently. With suitable calibration, the in vitro model can also be used to assess composite systems in a more clinically relevant manner. Copyright © 2017 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  8. Sequential optimization of methotrexate encapsulation in micellar nano-networks of polyethyleneimine ionomer containing redox-sensitive cross-links.

    Science.gov (United States)

    Abolmaali, Samira Sadat; Tamaddon, Ali; Yousefi, Gholamhossein; Javidnia, Katayoun; Dinarvand, Rasoul

    2014-01-01

    A functional polycation nanonetwork was developed for delivery of water soluble chemotherapeutic agents. The complexes of polyethyleneimine grafted methoxy polyethylene glycol (PEI-g-mPEG) and Zn(2+) were utilized as the micellar template for cross-linking with dithiodipropionic acid, followed by an acidic pH dialysis to remove the metal ion from the micellar template. The synthesis method was optimized according to pH, the molar ratio of Zn(2+), and the cross-link ratio. The atomic force microscopy showed soft, discrete, and uniform nano-networks. They were sensitive to the simulated reductive environment as determined by Ellman's assay. They showed few positive ζ potential and an average hydrodynamic diameter of 162±10 nm, which decreased to 49±11 nm upon dehydration. The ionic character of the nano-networks allowed the achievement of a higher-loading capacity of methotrexate (MTX), approximately 57% weight per weight, depending on the cross-link and the drug feed ratios. The nano-networks actively loaded with MTX presented some suitable properties, such as the hydrodynamic size of 117±16 nm, polydispersity index of 0.22, and a prolonged swelling-controlled release profile over 24 hours that boosted following reductive activation of the nanonetwork biodegradation. Unlike the PEI ionomer, the nano-networks provided an acceptable cytotoxicity profile. The drug-loaded nano-networks exhibited more specific cytotoxicity against human hepatocellular carcinoma cells if compared to free MTX at concentrations above 1 μM. The enhanced antitumor activity in vitro might be attributed to endocytic entry of MTX-loaded nano-networks that was found in the epifluorescence microscopy experiment for the fluorophore-labeled nano-networks.

  9. Input Harmonic Analysis on the Slim DC-Link Drive Using Harmonic State Space Model

    DEFF Research Database (Denmark)

    Yang, Feng; Kwon, Jun Bum; Wang, Xiongfei

    2017-01-01

    The harmonic performance of the slim dc-link adjustable speed drives has shown good performance in some studies but poor in some others. The contradiction indicates that a feasible theoretical analysis is still lacking to characterize the harmonic distortion for the slim dc-link drive. Considerin...... results of the slim dc-link drive, loaded up to 2.0 kW, are presented to validate the theoretical analysis....... variation according to the switching instant, the harmonics at the steady-state condition, as well as the coupling between the multiple harmonic impedances. By using this model, the impaction on the harmonics performance by the film capacitor and the grid inductance is derived. Simulation and experimental...

  10. Reconceptualizing perceptual load as a rate problem: The role of time in the allocation of selective attention.

    Science.gov (United States)

    Li, Zhi; Xin, Keyun; Li, Wei; Li, Yanzhe

    2018-04-30

    In the literature about allocation of selective attention, a widely studied question is when will attention be allocated to information that is clearly irrelevant to the task at hand. The present study, by using convergent evidence, demonstrated that there is a trade-off between quantity of information present in a display and the time allowed to process it. Specifically, whether or not there is interference from irrelevant distractors depends not only on the amount of information present, but also on the amount of time allowed to process that information. When processing time is calibrated to the amount of information present, irrelevant distractors can be selectively ignored successfully. These results suggest that the perceptual load in the load theory of selective attention (i.e., Lavie, 2005) should be thought about as a dynamic rate problem rather than a static capacity limitation. The authors thus propose that rather than conceiving of perceptual load as a quantity of information, they should consider it as a quantity of information per unit of time. In other words, it is the relationship between the quantity of information in the task and the time for processing the information that determines the allocation of selective attention. Thus, the present findings extended load theory, allowing it to explain findings that were previously considered as counter evidence of load theory. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  11. Distribution load forecast with interactive correction of horizon loads

    International Nuclear Information System (INIS)

    Glamochanin, V.; Andonov, D.; Gagovski, I.

    1994-01-01

    This paper presents the interactive distribution load forecast application that performs the distribution load forecast with interactive correction of horizon loads. It consists of two major parts implemented in Fortran and Visual Basic. The Fortran part is used for the forecasts computations. It consists of two methods: Load Transfer Coupling Curve Fitting (LTCCF) and load Forecast Using Curve Shape Clustering (FUCSC). LTCCF is used to 'correct' the contaminated data because of load transfer among neighboring distribution areas. FUCSC uses curve shape clustering to forecast the distribution loads of small areas. The forecast for each small area is achieved by using the shape of corresponding cluster curve. The comparison of forecasted loads of the area with historical data will be used as a tool for the correction of the estimated horizon load. The Visual Basic part is used to provide flexible interactive user-friendly environment. (author). 5 refs., 3 figs

  12. Transport of phosphorus, wash load and suspended sediment in the River Varde A in southwest Jutland, Denmark

    DEFF Research Database (Denmark)

    Thodsen, Hans; Hasholt, Bent; Pejrup, Morten

    2004-01-01

    Total phosphorus (TP) concentrations, suspended sediment concentrations (SSC) and wash load have been measured at three river monitoring stations in the River Varde Angstrom system since 1998. This provides the possibility of studying the link between SSC and wash load and concentrations of TP...... at the end of a small impoundment. Transport rates at the upstream stations were 57% higher for suspended sediment and 27% higher for wash load than at the downstream station, while transport of TP was the same. This indicates that phosphorus is transported adhered to the finest grain size fractions that do...

  13. Formal and informal surveillance systems: how to build links

    Directory of Open Access Journals (Sweden)

    S. Desvaux

    2015-11-01

    Full Text Available Within the framework of highly pathogenic avian influenza (HPAI surveillance in Vietnam, interviews were carried out with poultry farmers and local animal health operators in two municipalities of the Red River delta with a view to documenting the circulation of health information concerning poultry (content of the information; method, scope and speed of circulation; actors involved; actions triggered as a result of the information received; economic and social incentives for disseminating or withholding information. The main results show that (i active informal surveillance networks exist, (ii the alert levels vary and the measures applied by the poultry farmers are myriad and often far-removed from the official recommendations, and (iii the municipal veterinarian is at the interface between the formal and the informal surveillance systems. The conclusions emphasize the need for the authorities to separate distinctly surveillance and control activities, and to regionalize control strategies, taking into account epidemiological specificities and social dynamics at local level.

  14. Effects of cognitive load on trusting behavior--an experiment using the trust game.

    Directory of Open Access Journals (Sweden)

    Katarzyna Samson

    Full Text Available Last decades have witnessed a progressing decline of social trust, which has been predominantly linked to worsening economic conditions and increasing social inequality. In the present research we propose a different type of explanation for the observed decline - cognitive load related to technological development and the accelerating pace of modern life. In an experimental study participants played the trust game while performing one of two different secondary tasks - listening to a disturbing noise or memorizing a sequence of characters - or with no additional task in the control condition. Results show that in both cognitive load conditions participants expressed significantly less trust in the trust game than in case of no cognitive load. Additionally, when cognitive resources were limited, participants' behavior was more impulsive than when their resources were fully available.

  15. Short-term load forecasting by a neuro-fuzzy based approach

    Energy Technology Data Exchange (ETDEWEB)

    Ruey-Hsun Liang; Ching-Chi Cheng [National Yunlin University of Science and Technology (China). Dept. of Electrical Engineering

    2002-02-01

    An approach based on an artificial neural network (ANN) combined with a fuzzy system is proposed for short-term load forecasting. This approach was developed in order to reach the desired short-term load forecasting in an efficient manner. Over the past few years, ANNs have attained the ability to manage a great deal of system complexity and are now being proposed as powerful computational tools. In order to select the appropriate load as the input for the desired forecasting, the Pearson analysis method is first applied to choose two historical record load patterns that are similar to the forecasted load pattern. These two load patterns and the required weather parameters are then fuzzified and input into a neural network for training or testing the network. The back-propagation (BP) neural network is applied to determine the preliminary forecasted load. In addition, the rule base for the fuzzy inference machine contains important linguistic membership function terms with knowledge in the form of fuzzy IF-THEN rules. This produces the load correction inference from the historical information and past forecasted load errors to obtain an inferred load error. Adding the inferred load error to the preliminary forecasted load, we can obtain the finial forecasted load. The effectiveness of the proposed approach to the short-term load-forecasting problem is demonstrated using practical data from the Taiwan Power Company (TPC). (Author)

  16. Better target detection in the presence of collinear flankers under high working memory load

    Directory of Open Access Journals (Sweden)

    Jan W. De Fockert

    2014-10-01

    Full Text Available There are multiple ways in which working memory can influence selective attention. Aside from the content-specific effects of working memory on selective attention, whereby attention is more likely to be directed towards information that matches the contents of working memory, the mere level of load on working memory has also been shown to have an effect on selective attention. Specifically, high load on working memory is associated with increased processing of irrelevant information. In most demonstrations of the effect to-date, this has led to impaired target performance, leaving open the possibility that the effect partly reflects an increase in general task difficulty under high load. Here we show that working memory load can result in a performance gain when processing of distracting information aids target performance. The facilitation in the detection of a low-contrast Gabor stimulus in the presence of collinear flanking Gabors was greater when load on a concurrent working memory task was high, compared to low. This finding suggests that working memory can interact with selective attention at an early stage in visual processing.

  17. Working memory load eliminates the survival processing effect.

    Science.gov (United States)

    Kroneisen, Meike; Rummel, Jan; Erdfelder, Edgar

    2014-01-01

    In a series of experiments, Nairne, Thompson, and Pandeirada (2007) demonstrated that words judged for their relevance to a survival scenario are remembered better than words judged for a scenario not relevant on a survival dimension. They explained this survival-processing effect by arguing that nature "tuned" our memory systems to process and remember fitness-relevant information. Kroneisen and Erdfelder (2011) proposed that it may not be survival processing per se that facilitates recall but the richness and distinctiveness with which information is encoded. To further test this account, we investigated how the survival processing effect is affected by cognitive load. If the survival processing effect is due to automatic processes or, alternatively, if survival processing is routinely prioritized in dual-task contexts, we would expect this effect to persist under cognitive load conditions. If the effect relies on cognitively demanding processes like richness and distinctiveness of encoding, however, the survival processing benefit should be hampered by increased cognitive load during encoding. Results were in line with the latter prediction, that is, the survival processing effect vanished under dual-task conditions.

  18. A new perspective on the perceptual selectivity of attention under load.

    Science.gov (United States)

    Giesbrecht, Barry; Sy, Jocelyn; Bundesen, Claus; Kyllingsbaek, Søren

    2014-05-01

    The human attention system helps us cope with a complex environment by supporting the selective processing of information relevant to our current goals. Understanding the perceptual, cognitive, and neural mechanisms that mediate selective attention is a core issue in cognitive neuroscience. One prominent model of selective attention, known as load theory, offers an account of how task demands determine when information is selected and an account of the efficiency of the selection process. However, load theory has several critical weaknesses that suggest that it is time for a new perspective. Here we review the strengths and weaknesses of load theory and offer an alternative biologically plausible computational account that is based on the neural theory of visual attention. We argue that this new perspective provides a detailed computational account of how bottom-up and top-down information is integrated to provide efficient attentional selection and allocation of perceptual processing resources. © 2014 New York Academy of Sciences.

  19. Literature review Quasi-static and Dynamic pile load tests : Primarily report on non-static pile load tests

    NARCIS (Netherlands)

    Huy, N.Q.

    2010-01-01

    Pile testing, which plays an importance role in the field of deep foundation design, is performed by static and non-static methods to provide information about the following issues: (Poulos, 1998) - The ultimate capacity of a single pile. - The load-displacement behavior of a pile. - The performance

  20. Uncovering missing links with cold ends

    Science.gov (United States)

    Zhu, Yu-Xiao; Lü, Linyuan; Zhang, Qian-Ming; Zhou, Tao

    2012-11-01

    To evaluate the performance of prediction of missing links, the known data are randomly divided into two parts, the training set and the probe set. We argue that this straightforward and standard method may lead to terrible bias, since in real biological and information networks, missing links are more likely to be links connecting low-degree nodes. We therefore study how to uncover missing links with low-degree nodes, namely links in the probe set are of lower degree products than a random sampling. Experimental analysis on ten local similarity indices and four disparate real networks reveals a surprising result that the Leicht-Holme-Newman index [E.A. Leicht, P. Holme, M.E.J. Newman, Vertex similarity in networks, Phys. Rev. E 73 (2006) 026120] performs the best, although it was known to be one of the worst indices if the probe set is a random sampling of all links. We further propose an parameter-dependent index, which considerably improves the prediction accuracy. Finally, we show the relevance of the proposed index to three real sampling methods: acquaintance sampling, random-walk sampling and path-based sampling.

  1. Material properties under intensive dynamic loading

    CERN Document Server

    Cherne, Frank J; Zhernokletov, Mikhail V; Glushak, B L; Zocher, Marvin A

    2007-01-01

    Understanding the physical and thermomechanical response of materials subjected to intensive dynamic loading is a challenge of great significance in engineering today. This volume assumes the task of gathering both experimental and diagnostic methods in one place, since not much information has been previously disseminated in the scientific literature.

  2. Neighborhood perceptions and allostatic load

    DEFF Research Database (Denmark)

    van Deurzen, Ioana; Rod, Naja Hulvej; Christensen, Ulla

    2016-01-01

    An influential argument explaining why living in certain neighborhoods can become harmful to one's health maintains that individuals can perceive certain characteristics of the neighborhood as threatening and the prolonged exposure to a threatening environment could induce chronic stress. Following...... this line of argumentation, in the present study we test whether subjective perceptions of neighborhood characteristics relate to an objective measure of stress-related physiological functioning, namely allostatic load (AL). We use a large dataset of 5280 respondents living in different regions of Denmark...... and we account for two alternative mechanisms, i.e., the objective characteristics of the living environment and the socio-economic status of individuals. Our results support the chronic stress mechanisms linking neighborhood quality to health. Heightened perceptions of disorder and pollution were found...

  3. Spore load and immune response of honey bees naturally infected by Nosema ceranae.

    Science.gov (United States)

    Li, Wenfeng; Evans, Jay D; Li, Jianghong; Su, Songkun; Hamilton, Michele; Chen, Yanping

    2017-12-01

    Nosema ceranae causes widespread infection in adult workers of European honey bees, Apis mellifera, and has often been linked to honey bee colony losses worldwide. Previous investigations of honey bee immune response to N. ceranae infection were largely based on laboratory experiment, however, little is known about the immune response of honey bees that are naturally infected by N. ceranae. Here, we compared the infection levels of N. ceranae in three different categories of adult bees (emergent bees, nurses, and foragers) and detected the host immune response to the N. ceranae infection under natural conditions. Our studies showed that the Nosema spore load and infection prevalence varied among the different types of adult workers, and both of them increased as honey bees aged: No infection was detected in emergent bees, nurses had a medium spore load and prevalence, while foragers were with the highest Nosema infection level and prevalence. Quantification of the mRNA levels of antimicrobial peptides (abaecin, apidaecin, defensin-1, defensin-2, and hymenoptaecin) and microbial recognition proteins (PGRP-S1, PGRP-S2, PGRP-S3, PGRP-LC, GNBP1-1, and GNBP1-2) confirmed the involvement of the Toll and/or Imd immune pathways in the host response to N. ceranae infection, and revealed an activation of host immune response by N. ceranae infection under natural conditions. Additionally, the levels of immune response were positively correlated with the Nosema spore loads in the infected bees. The information gained from this study will be relevant to the predictive modeling of honey bee disease dynamics for Nosema disease prevention and management.

  4. Effect of Drug Loading Method and Drug Physicochemical Properties on the Material and Drug Release Properties of Poly (Ethylene Oxide Hydrogels for Transdermal Delivery

    Directory of Open Access Journals (Sweden)

    Rachel Shet Hui Wong

    2017-07-01

    Full Text Available Novel poly (ethylene oxide (PEO hydrogel films were synthesized via UV cross-linking with pentaerythritol tetra-acrylate (PETRA as cross-linking agent. The purpose of this work was to develop a novel hydrogel film suitable for passive transdermal drug delivery via skin application. Hydrogels were loaded with model drugs (lidocaine hydrochloride (LID, diclofenac sodium (DIC and ibuprofen (IBU via post-loading and in situ loading methods. The effect of loading method and drug physicochemical properties on the material and drug release properties of medicated film samples were characterized using scanning electron microscopy (SEM, swelling studies, differential scanning calorimetry (DSC, fourier transform infrared spectroscopy (FT-IR, tensile testing, rheometry, and drug release studies. In situ loaded films showed better drug entrapment within the hydrogel network and also better polymer crystallinity. High drug release was observed from all studied formulations. In situ loaded LID had a plasticizing effect on PEO hydrogel, and films showed excellent mechanical properties and prolonged drug release. The drug release mechanism for the majority of medicated PEO hydrogel formulations was determined as both drug diffusion and polymer chain relaxation, which is highly desirable for controlled release formulations.

  5. Multicycle Optimization of Advanced Gas-Cooled Reactor Loading Patterns Using Genetic Algorithms

    International Nuclear Information System (INIS)

    Ziver, A. Kemal; Carter, Jonathan N.; Pain, Christopher C.; Oliveira, Cassiano R.E. de; Goddard, Antony J. H.; Overton, Richard S.

    2003-01-01

    A genetic algorithm (GA)-based optimizer (GAOPT) has been developed for in-core fuel management of advanced gas-cooled reactors (AGRs) at HINKLEY B and HARTLEPOOL, which employ on-load and off-load refueling, respectively. The optimizer has been linked to the reactor analysis code PANTHER for the automated evaluation of loading patterns in a two-dimensional geometry, which is collapsed from the three-dimensional reactor model. GAOPT uses a directed stochastic (Monte Carlo) algorithm to generate initial population members, within predetermined constraints, for use in GAs, which apply the standard genetic operators: selection by tournament, crossover, and mutation. The GAOPT is able to generate and optimize loading patterns for successive reactor cycles (multicycle) within acceptable CPU times even on single-processor systems. The algorithm allows radial shuffling of fuel assemblies in a multicycle refueling optimization, which is constructed to aid long-term core management planning decisions. This paper presents the application of the GA-based optimization to two AGR stations, which apply different in-core management operational rules. Results obtained from the testing of GAOPT are discussed

  6. Load forecasting of supermarket refrigeration

    DEFF Research Database (Denmark)

    Rasmussen, Lisa Buth; Bacher, Peder; Madsen, Henrik

    2016-01-01

    methods for predicting the regimes are tested. The dynamic relation between the weather and the load is modeled by simple transfer functions and the non-linearities are described using spline functions. The results are thoroughly evaluated and it is shown that the spline functions are suitable...... for handling the non-linear relations and that after applying an auto-regressive noise model the one-step ahead residuals do not contain further significant information....... in Denmark. Every hour the hourly electrical load for refrigeration is forecasted for the following 42 h. The forecast models are adaptive linear time series models. The model has two regimes; one for opening hours and one for closing hours, this is modeled by a regime switching model and two different...

  7. Characterization of Na+-linked and Na+-independent Cl-/HCO3- exchange systems in Chinese hamster lung fibroblasts

    International Nuclear Information System (INIS)

    Cassel, D.; Scharf, O.; Rotman, M.; Cragoe, E.J. Jr.; Katz, M.

    1988-01-01

    The PS120 variant of Chinese hamster lung fibroblasts which lacks Na + /H + exchange activity was used to investigate bicarbonate transport systems and their role in intracellular pH (pH/sub i/) regulation. When pH/sub i/ was decreased by acid load, bicarbonate caused pH/sub i/ increase and stimulated 36 Cl - efflux from the cells, both in a Na + -dependent manner. These results together with previous findings that bicarbonate stimulates 22 Na + uptake in PS120 cells demonstrate the presence of a Na + -linked Cl - /HCO 3 - exchange system. In cells with normal initial pH/sub i/, bicarbonate caused Na + -independent pH/sub i/ increase in Cl - -free solutions and stimulated Na + -independent 36 Cl - efflux, indicating that a Na + -independent Cl - /HCO 3 - exchanger is also present in the cell. Na + -linked and Na + -independent Cl - /HCO 3- exchange is apparently mediated by two distinct systems, since a [(tetrahydrofluorene-7-yl)oxy]acetic acid derivative selectively inhibits the Na + -independent exchanger. An additional distinctive features is a 10-fold lower affinity for chloride of the Na + -linked exchanger. The Na + -linked and Na + -independent Cl - /HCO 3 - exchange systems are likely to protect the cell from acid and alkaline load, respectively

  8. Impact of Spatial and Verbal Short-Term Memory Load on Auditory Spatial Attention Gradients.

    Science.gov (United States)

    Golob, Edward J; Winston, Jenna; Mock, Jeffrey R

    2017-01-01

    Short-term memory load can impair attentional control, but prior work shows that the extent of the effect ranges from being very general to very specific. One factor for the mixed results may be reliance on point estimates of memory load effects on attention. Here we used auditory attention gradients as an analog measure to map-out the impact of short-term memory load over space. Verbal or spatial information was maintained during an auditory spatial attention task and compared to no-load. Stimuli were presented from five virtual locations in the frontal azimuth plane, and subjects focused on the midline. Reaction times progressively increased for lateral stimuli, indicating an attention gradient. Spatial load further slowed responses at lateral locations, particularly in the left hemispace, but had little effect at midline. Verbal memory load had no (Experiment 1), or a minimal (Experiment 2) influence on reaction times. Spatial and verbal load increased switch costs between memory encoding and attention tasks relative to the no load condition. The findings show that short-term memory influences the distribution of auditory attention over space; and that the specific pattern depends on the type of information in short-term memory.

  9. Impact of Spatial and Verbal Short-Term Memory Load on Auditory Spatial Attention Gradients

    Directory of Open Access Journals (Sweden)

    Edward J. Golob

    2017-11-01

    Full Text Available Short-term memory load can impair attentional control, but prior work shows that the extent of the effect ranges from being very general to very specific. One factor for the mixed results may be reliance on point estimates of memory load effects on attention. Here we used auditory attention gradients as an analog measure to map-out the impact of short-term memory load over space. Verbal or spatial information was maintained during an auditory spatial attention task and compared to no-load. Stimuli were presented from five virtual locations in the frontal azimuth plane, and subjects focused on the midline. Reaction times progressively increased for lateral stimuli, indicating an attention gradient. Spatial load further slowed responses at lateral locations, particularly in the left hemispace, but had little effect at midline. Verbal memory load had no (Experiment 1, or a minimal (Experiment 2 influence on reaction times. Spatial and verbal load increased switch costs between memory encoding and attention tasks relative to the no load condition. The findings show that short-term memory influences the distribution of auditory attention over space; and that the specific pattern depends on the type of information in short-term memory.

  10. The integrated workstation: A common, consistent link between nuclear plant personnel and plant information and computerized resources

    International Nuclear Information System (INIS)

    Wood, R.T.; Knee, H.E.; Mullens, J.A.; Munro, J.K. Jr.; Swail, B.K.; Tapp, P.A.

    1993-01-01

    The increasing use of computer technology in the US nuclear power industry has greatly expanded the capability to obtain, analyze, and present data about the plant to station personnel. Data concerning a power plant's design, configuration, operational and maintenance histories, and current status, and the information that can be derived from them, provide the link between the plant and plant staff. It is through this information bridge that operations, maintenance and engineering personnel understand and manage plant performance. However, it is necessary to transform the vast quantity of data available from various computer systems and across communications networks into clear, concise, and coherent information. In addition, it is important to organize this information into a consolidated, structured form within an integrated environment so that various users throughout the plant have ready access at their local station to knowledge necessary for their tasks. Thus, integrated workstations are needed to provide the inquired information and proper software tools, in a manner that can be easily understood and used, to the proper users throughout the plant. An effort is underway at the Oak Ridge National Laboratory to address this need by developing Integrated Workstation functional requirements and implementing a limited-scale prototype demonstration. The integrated Workstation requirements will define a flexible, expandable computer environment that permits a tailored implementation of workstation capabilities and facilitates future upgrades to add enhanced applications. The functionality to be supported by the integrated workstation and inherent capabilities to be provided by the workstation environment win be described. In addition, general technology areas which are to be addressed in the Integrated Workstation functional requirements will be discussed

  11. Load theory behind the wheel; perceptual and cognitive load effects.

    Science.gov (United States)

    Murphy, Gillian; Greene, Ciara M

    2017-09-01

    Perceptual Load Theory has been proposed as a resolution to the longstanding early versus late selection debate in cognitive psychology. There is much evidence in support of Load Theory but very few applied studies, despite the potential for the model to shed light on everyday attention and distraction. Using a driving simulator, the effect of perceptual and cognitive load on drivers' visual search was assessed. The findings were largely in line with Load Theory, with reduced distractor processing under high perceptual load, but increased distractor processing under high cognitive load. The effect of load on driving behaviour was also analysed, with significant differences in driving behaviour under perceptual and cognitive load. In addition, the effect of perceptual load on drivers' levels of awareness was investigated. High perceptual load significantly increased inattentional blindness and deafness, for stimuli that were both relevant and irrelevant to driving. High perceptual load also increased RTs to hazards. The current study helps to advance Load Theory by illustrating its usefulness outside of traditional paradigms. There are also applied implications for driver safety and roadway design, as the current study suggests that perceptual and cognitive load are important factors in driver attention. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  12. Buffer-Aided Relaying with Adaptive Link Selection

    DEFF Research Database (Denmark)

    Zlatanov, Nikola; Schober, Robert; Popovski, Petar

    2013-01-01

    In this paper, we consider a simple network consisting of a source, a half-duplex decode-and-forward relay, and a destination. We propose a new relaying protocol employing adaptive link selection, i.e., in any given time slot, based on the channel state information of the source-relay and the relay......-destination link a decision is made whether the source or the relay transmits. In order to avoid data loss at the relay, adaptive link selection requires the relay to be equipped with a buffer such that data can be queued until the relay-destination link is selected for transmission. We study both delay......-constrained and delay-unconstrained transmission. For the delay-unconstrained case, we characterize the optimal link selection policy, derive the corresponding throughput, and develop an optimal power allocation scheme. For the delay-constrained case, we propose to starve the buffer of the relay by choosing...

  13. Changes in resonance frequency analysis assessed by Osstell mentor during osseointegration: comparison between immediately loaded implants and control implants without load

    Directory of Open Access Journals (Sweden)

    M. González-Jaranay

    2014-10-01

    Full Text Available Aim: The aim of this prospective clinical study was to evaluate the changes in resonance frequency analysis (RFA, assessed by Osstell Mentor, obtaining information on the implant stability quotient (ISQ during implants tissue integration for immediately loaded and non-loaded control implants. Materials and methods: A total of 40 implants, 20 implants with no immediate loading (control and 20 immediately loaded implants (test, were placed in 15 patients. ISQ implants was evaluated at baseline and at 6 and 8 weeks. Provisional crowns were removed at 8 weeks, when the definitive restoration was placed. Data of control and test implants and maxillary and mandibular areas were statistically compared. Results: At 8 weeks, all implants were integrated and there were no major postoperative complications. A statistically significant difference was found only at baseline between test and control maxillary implants (p=0.009 but not at 6 or 8 weeks (p>0.05. Conclusion: Immediate loading procedures may be applied with primary stability ISQ values >60 and inserted with a force of ≥30 N. The Osstell Mentor RFA may offer an objective method to determine when implant stability is adequate for immediate loading.

  14. Cross-link guided molecular modeling with ROSETTA.

    Directory of Open Access Journals (Sweden)

    Abdullah Kahraman

    Full Text Available Chemical cross-links identified by mass spectrometry generate distance restraints that reveal low-resolution structural information on proteins and protein complexes. The technology to reliably generate such data has become mature and robust enough to shift the focus to the question of how these distance restraints can be best integrated into molecular modeling calculations. Here, we introduce three workflows for incorporating distance restraints generated by chemical cross-linking and mass spectrometry into ROSETTA protocols for comparative and de novo modeling and protein-protein docking. We demonstrate that the cross-link validation and visualization software Xwalk facilitates successful cross-link data integration. Besides the protocols we introduce XLdb, a database of chemical cross-links from 14 different publications with 506 intra-protein and 62 inter-protein cross-links, where each cross-link can be mapped on an experimental structure from the Protein Data Bank. Finally, we demonstrate on a protein-protein docking reference data set the impact of virtual cross-links on protein docking calculations and show that an inter-protein cross-link can reduce on average the RMSD of a docking prediction by 5.0 Å. The methods and results presented here provide guidelines for the effective integration of chemical cross-link data in molecular modeling calculations and should advance the structural analysis of particularly large and transient protein complexes via hybrid structural biology methods.

  15. Plastic limit loads for cylindrical shell intersections under combined loading

    International Nuclear Information System (INIS)

    Skopinsky, V.N.; Berkov, N.A.; Vogov, R.A.

    2015-01-01

    In this research, applied methods of nonlinear analysis and results of determining the plastic limit loads for shell intersection configurations under combined internal pressure, in-plane moment and out-plane moment loadings are presented. The numerical analysis of shell intersections is performed using the finite element method, geometrically nonlinear shell theory in quadratic approximation and plasticity theory. For determining the load parameter of proportional combined loading, the developed maximum criterion of rate of change of relative plastic work is employed. The graphical results for model of cylindrical shell intersection under different two-parameter combined loadings (as generalized plastic limit load curves) and three-parameter combined loading (as generalized plastic limit load surface) are presented on the assumption that the internal pressure, in-plane moment and out-plane moment loads were applied in a proportional manner. - Highlights: • This paper presents nonlinear two-dimensional FE analysis for shell intersections. • Determining the plastic limit loads under combined loading is considered. • Developed maximum criterion of rate of change of relative plastic work is employed. • Plastic deformation mechanism in shell intersections is discussed. • Results for generalized plastic limit load curves of branch intersection are presented

  16. The effect of perceptual load on tactile spatial attention: Evidence from event-related potentials.

    Science.gov (United States)

    Gherri, Elena; Berreby, Fiona

    2017-10-15

    To investigate whether tactile spatial attention is modulated by perceptual load, behavioural and electrophysiological measures were recorded during two spatial cuing tasks in which the difficulty of the target/non-target discrimination was varied (High and Low load tasks). Moreover, to study whether attentional modulations by load are sensitive to the availability of visual information, the High and Low load tasks were carried out under both illuminated and darkness conditions. ERPs to cued and uncued non-targets were compared as a function of task (High vs. Low load) and illumination condition (Light vs. Darkness). Results revealed that the locus of tactile spatial attention was determined by a complex interaction between perceptual load and illumination conditions during sensory-specific stages of processing. In the Darkness, earlier effects of attention were present in the High load than in the Low load task, while no difference between tasks emerged in the Light. By contrast, increased load was associated with stronger attention effects during later post-perceptual processing stages regardless of illumination conditions. These findings demonstrate that ERP correlates of tactile spatial attention are strongly affected by the perceptual load of the target/non-target discrimination. However, differences between illumination conditions show that the impact of load on tactile attention depends on the presence of visual information. Perceptual load is one of the many factors that contribute to determine the effects of spatial selectivity in touch. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Immune networks: multi-tasking capabilities at medium load

    Science.gov (United States)

    Agliari, E.; Annibale, A.; Barra, A.; Coolen, A. C. C.; Tantari, D.

    2013-08-01

    Associative network models featuring multi-tasking properties have been introduced recently and studied in the low-load regime, where the number P of simultaneously retrievable patterns scales with the number N of nodes as P ˜ log N. In addition to their relevance in artificial intelligence, these models are increasingly important in immunology, where stored patterns represent strategies to fight pathogens and nodes represent lymphocyte clones. They allow us to understand the crucial ability of the immune system to respond simultaneously to multiple distinct antigen invasions. Here we develop further the statistical mechanical analysis of such systems, by studying the medium-load regime, P ˜ Nδ with δ ∈ (0, 1]. We derive three main results. First, we reveal the nontrivial architecture of these networks: they exhibit a high degree of modularity and clustering, which is linked to their retrieval abilities. Second, by solving the model we demonstrate for δ frameworks are required to achieve effective retrieval.

  18. How much is too much? (Part 2) International Olympic Committee consensus statement on load in sport and risk of illness

    Science.gov (United States)

    Schwellnus, Martin; Alonso, Juan-Manuel; Bahr, Roald; Clarsen, Ben; Dijkstra, H Paul; Gabbett, Tim J; Gleeson, Michael; Hutchinson, Mark R; Janse Van Rensburg, Christa; Meeusen, Romain; Orchard, John W; Pluim, Babette M; Raftery, Martin; Budgett, Richard; Engebretsen, Lars

    2016-01-01

    The modern-day athlete participating in elite sports is exposed to high training loads and increasingly saturated competition calendar. Emerging evidence indicates that inappropriate load management is a significant risk factor for acute illness and the overtraining syndrome. The IOC convened an expert group to review the scientific evidence for the relationship of load—including rapid changes in training and competition load, competition calendar congestion, psychological load and travel—and health outcomes in sport. This paper summarises the results linking load to risk of illness and overtraining in athletes, and provides athletes, coaches and support staff with practical guidelines for appropriate load management to reduce the risk of illness and overtraining in sport. These include guidelines for prescription of training and competition load, as well as for monitoring of training, competition and psychological load, athlete well-being and illness. In the process, urgent research priorities were identified. PMID:27535991

  19. “Nitrogen Budgets for the Mississippi River Basin using the linked EPIC-CMAQ-NEWS Models”

    Science.gov (United States)

    Presentation on the results from the 3 linked models, EPIC (USDA), CMAQ and NEWS to analyze a scenario of increased corn production related to biofuels together with Clean Air Act emission reductions across the US and the resultant effect on nitrogen loading to the Gulf of Mexico...

  20. How much is too much? (Part 1) International Olympic Committee consensus statement on load in sport and risk of injury.

    Science.gov (United States)

    Soligard, Torbjørn; Schwellnus, Martin; Alonso, Juan-Manuel; Bahr, Roald; Clarsen, Ben; Dijkstra, H Paul; Gabbett, Tim; Gleeson, Michael; Hägglund, Martin; Hutchinson, Mark R; Janse van Rensburg, Christa; Khan, Karim M; Meeusen, Romain; Orchard, John W; Pluim, Babette M; Raftery, Martin; Budgett, Richard; Engebretsen, Lars

    2016-09-01

    Athletes participating in elite sports are exposed to high training loads and increasingly saturated competition calendars. Emerging evidence indicates that poor load management is a major risk factor for injury. The International Olympic Committee convened an expert group to review the scientific evidence for the relationship of load (defined broadly to include rapid changes in training and competition load, competition calendar congestion, psychological load and travel) and health outcomes in sport. We summarise the results linking load to risk of injury in athletes, and provide athletes, coaches and support staff with practical guidelines to manage load in sport. This consensus statement includes guidelines for (1) prescription of training and competition load, as well as for (2) monitoring of training, competition and psychological load, athlete well-being and injury. In the process, we identified research priorities. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  1. Scientometrics and information retrieval: weak-links revitalized

    NARCIS (Netherlands)

    Mayr, Philipp; Scharnhorst, Andrea

    This special issue brings together eight papers from experts of communities which often have been perceived as different once: bibliometrics, scientometrics and in- formetrics on the one side and information retrieval on the other. The idea of this special issue started at the workshop ‘‘Combining

  2. Immune networks: multi-tasking capabilities at medium load

    International Nuclear Information System (INIS)

    Agliari, E; Annibale, A; Barra, A; Coolen, A C C; Tantari, D

    2013-01-01

    Associative network models featuring multi-tasking properties have been introduced recently and studied in the low-load regime, where the number P of simultaneously retrievable patterns scales with the number N of nodes as P ∼ log N. In addition to their relevance in artificial intelligence, these models are increasingly important in immunology, where stored patterns represent strategies to fight pathogens and nodes represent lymphocyte clones. They allow us to understand the crucial ability of the immune system to respond simultaneously to multiple distinct antigen invasions. Here we develop further the statistical mechanical analysis of such systems, by studying the medium-load regime, P ∼ N δ with δ ∈ (0, 1]. We derive three main results. First, we reveal the nontrivial architecture of these networks: they exhibit a high degree of modularity and clustering, which is linked to their retrieval abilities. Second, by solving the model we demonstrate for δ < 1 the existence of large regions in the phase diagram where the network can retrieve all stored patterns simultaneously. Finally, in the high-load regime δ = 1 we find that the system behaves as a spin-glass, suggesting that finite-connectivity frameworks are required to achieve effective retrieval. (paper)

  3. Health and Environment Linked for Information Exchange in Atlanta (HELIX-Atlanta): A Pilot Tracking System

    Science.gov (United States)

    Rickman, Doug; Shire, J.; Qualters, J.; Mitchell, K.; Pollard, S.; Rao, R.; Kajumba, N.; Quattrochi, D.; Estes, M., Jr.; Meyer, P.; hide

    2009-01-01

    Objectives. To provide an overview of four environmental public health surveillance projects developed by CDC and its partners for the Health and Environment Linked for Information Exchange, Atlanta (HELIX-Atlanta) and to illustrate common issues and challenges encountered in developing an environmental public health tracking system. Methods. HELIX-Atlanta, initiated in October 2003 to develop data linkage and analysis methods that can be used by the National Environmental Public Health Tracking Network (Tracking Network), conducted four projects. We highlight the projects' work, assess attainment of the HELIX-Atlanta goals and discuss three surveillance attributes. Results. Among the major challenges was the complexity of analytic issues which required multidiscipline teams with technical expertise. This expertise and the data resided across multiple organizations. Conclusions:Establishing formal procedures for sharing data, defining data analysis standards and automating analyses, and committing staff with appropriate expertise is needed to support wide implementation of environmental public health tracking.

  4. Opposite effects of capacity load and resolution load on distractor processing.

    Science.gov (United States)

    Zhang, Weiwei; Luck, Steven J

    2015-02-01

    According to the load theory of attention, an increased perceptual load reduces distractor processing whereas an increased working memory load facilitates distractor processing. Here we raise the possibility that the critical distinction may instead be between an emphasis on resolution and an emphasis on capacity. That is, perceptual load manipulations typically emphasize resolution (fine-grained discriminations), whereas working memory load manipulations typically emphasize capacity (simultaneous processing of multiple relevant stimuli). To test the plausibility of this hypothesis, we used a visual working memory task that emphasized either the number of items to be stored (capacity load, retaining 2 vs. 4 colors) or the precision of the representations (resolution load, detecting small vs. large color changes). We found that an increased capacity load led to increased flanker interference (a measure of distractor processing), whereas an increased resolution load led to reduced flanker interference. These opposite effects of capacity load and resolution load on distractor processing mirror the previously described opposite effects of perceptual load and working memory load.

  5. Bridging information requirements and information needs assessment: do scenarios and vignettes provide a link?

    Directory of Open Access Journals (Sweden)

    Christine Urquhart

    2001-01-01

    Full Text Available The aim of the paper is to compare the philosophies of the vignette and critical incident techniques in information behaviour research, with the methodologies used in object oriented analysis such as use case scenarios and CRC (class, responsibility, collaboration cards. The principles of object oriented analysis are outlined, noting the emphasis on obtaining the "storyline" or "scripts" for information requirements analysis through use cases and CRC cards.  The critical incident technique and vignettes are used to obtain valid interpretations of users" information behaviour, using a storyline approach for data collection (and analysis which is similar to that of object oriented analysis. Some examples illustrate how techniques developed in object oriented analysis could be used for data display in information behaviour studies. Concludes that the methods developed by software engineering could be adapted usefully for information behaviour research.

  6. Entity Linking Leveraging the GeoDeepDive Cyberinfrastructure and Managing Uncertainty with Provenance.

    Science.gov (United States)

    Maio, R.; Arko, R. A.; Lehnert, K.; Ji, P.

    2017-12-01

    Unlocking the full, rich, network of links between the scientific literature and the real world entities to which data correspond - such as field expeditions (cruises) on oceanographic research vessels and physical samples collected during those expeditions - remains a challenge for the geoscience community. Doing so would enable data reuse and integration on a broad scale; making it possible to inspect the network and discover, for example, all rock samples reported in the scientific literature found within 10 kilometers of an undersea volcano, and associated geochemical analyses. Such a capability could facilitate new scientific discoveries. The GeoDeepDive project provides negotiated access to 4.2+ million documents from scientific publishers, enabling text and document mining via a public API and cyberinfrastructure. We mined this corpus using entity linking techniques, which are inherently uncertain, and recorded provenance information about each link. This opens the entity linking methodology to scrutiny, and enables downstream applications to make informed assessments about the suitability of an entity link for consumption. A major challenge is how to model and disseminate the provenance information. We present results from entity linking between journal articles, research vessels and cruises, and physical samples from the Petrological Database (PetDB), and incorporate Linked Data resources such as cruises in the Rolling Deck to Repository (R2R) catalog where possible. Our work demonstrates the value and potential of the GeoDeepDive cyberinfrastructure in combination with Linked Data infrastructure provided by the EarthCube GeoLink project. We present a research workflow to capture provenance information that leverages the World Wide Web Consortium (W3C) recommendation PROV Ontology.

  7. Using of residential load curves obtained for determination of the load diversity, and loading of distribution transformers; Utilizacao de curvas de carga de consumidores industriais medidas para determinacao de diversidade de carga, e carregamento de transformadores de distribuicao

    Energy Technology Data Exchange (ETDEWEB)

    Ferrari, Eduardo Luiz; Jardini, Jose Antonio

    1996-07-01

    This work presents some applications of the residential loads, obtained from measurements conducted by the electric power utilities in the state of Sao Paulo , Brazil. During the first application, curve of coincidence of load peaks occurrence, as function of the number of consumers simultaneously connected to a specific residential distribution transformer. This curve provides a information on the number of consumers presenting coincident load peaks coincident relative to the total numbers of consumers connected to the distribution transformer. Those curves allow to obtain the diversity curves. The second application focused the calculation of the distribution transformer life reduction.

  8. Investigation towards link-enriched video: user information needs for environmental opinion-forming and decision-making

    NARCIS (Netherlands)

    A.C. Palumbo

    2012-01-01

    htmlabstractLink-enriched video can support users in processes of environmental opinion-forming and decision-making. For this, audiovisual content must be represented and annotated to enable automatic link generation and computer manipulation. Given the time and budget constraints of

  9. Study of nonpoint source nutrient loading in the Patuxent River basin, Maryland

    Science.gov (United States)

    Preston, S.D.

    1997-01-01

    Study of nonpoint-source (NPS) nutrient loading in Maryland has focused on the Patuxent watershed because of its importance and representativeness of conditions in the State. Evaluation of NPS nutrient loading has been comprehensive and has included long-term monitoring, detailed watershed modeling, and synoptic sampling studies. A large amount of information has been compiled for the watershed and that information is being used to identify primary controls and efficient management strategies for NPS nutrient loading. Results of the Patuxent NPS study have identified spatial trends in water quality that appear to be related to basin charcteristics such as land use, physiography, andgeology. Evaluation of the data compiled by the study components is continuing and is expected to provide more detailed assessments of the reasons for spatial trends. In particular, ongoing evaluation of the watershed model output is expected to provide detailed information on the relative importance of nutrient sources and transport pathways across the entire watershed. Planned future directions of NPS evaluation in the State of Maryland include continued study of water quality in the Patuxent watershed and a shift in emphasis to a statewide approach. Eventually, the statewide approach will become the primary approach usedby the State to evaluate NPS loading. The information gained in the Patuxent study and the tools developed will represent valuable assets indeveloping the statewide NPS assessment program.

  10. Load testing circuit

    DEFF Research Database (Denmark)

    2009-01-01

    A load testing circuit a circuit tests the load impedance of a load connected to an amplifier. The load impedance includes a first terminal and a second terminal, the load testing circuit comprising a signal generator providing a test signal of a defined bandwidth to the first terminal of the load...

  11. Linking lab and field

    International Nuclear Information System (INIS)

    Cronje, P.B.

    1988-01-01

    The multitude of different supplements recommended for animals grazing natural pastures, which testifies to the need for a metabolic basis for supplementary feeding practices. The first approach to this problem was to simulate different feeding conditions in the laboratory, where the metabolic responses of body tissues to changes in the supply of purified nutrients could be studied using radioisotope techniques. The second step was to link these fundamental studies to field conditions. The results of these studies suggest that the efficiency of feed conversion and growth rates of ruminants grazing winter pastures in the highveld region of South Africa could be substantially improved by strategic supplementation with glucose precursors. Acetate clearance rate represents a valuable link in the process of applying information obtained from controlled laboratory experiments to field conditions. As this technique is inexpensive, quick and simple to carry out, it is ideally suited to application under field conditions where the use of isotopes is impractical. By providing a link with field conditions, it greatly extended the scope and practical application of isotope tracer techniques

  12. 46 CFR 154.1730 - Ethylene oxide: Loading and off loading.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Ethylene oxide: Loading and off loading. 154.1730... Operating Requirements § 154.1730 Ethylene oxide: Loading and off loading. (a) The master shall ensure that before ethylene oxide is loaded into a cargo tank: (1) The tank is thoroughly clean, dry, and free of...

  13. Intelligent harmonic load model based on neural networks

    Science.gov (United States)

    Ji, Pyeong-Shik; Lee, Dae-Jong; Lee, Jong-Pil; Park, Jae-Won; Lim, Jae-Yoon

    2007-12-01

    In this study, we developed a RBFNs(Radial Basis Function Networks) based load modeling method with harmonic components. The developed method implemented by using harmonic information as well as fundamental frequency and voltage which are essential input factors in conventional method. Thus, the proposed method makes it possible to effectively estimate load characteristics in power lines with harmonics. The RBFNs have certain advantage such as simple structure and rapid computation ability compared with multilayer perceptron which is extensively applied for load modeling. To show the effectiveness, the proposed method has been intensively tested with various dataset acquired under the different frequency and voltage and compared it with conventional methods such as polynominal 2nd equation method, MLP and RBF without considering harmonic components.

  14. Link Prediction via Convex Nonnegative Matrix Factorization on Multiscale Blocks

    Directory of Open Access Journals (Sweden)

    Enming Dong

    2014-01-01

    Full Text Available Low rank matrices approximations have been used in link prediction for networks, which are usually global optimal methods and lack of using the local information. The block structure is a significant local feature of matrices: entities in the same block have similar values, which implies that links are more likely to be found within dense blocks. We use this insight to give a probabilistic latent variable model for finding missing links by convex nonnegative matrix factorization with block detection. The experiments show that this method gives better prediction accuracy than original method alone. Different from the original low rank matrices approximations methods for link prediction, the sparseness of solutions is in accord with the sparse property for most real complex networks. Scaling to massive size network, we use the block information mapping matrices onto distributed architectures and give a divide-and-conquer prediction method. The experiments show that it gives better results than common neighbors method when the networks have a large number of missing links.

  15. Peak load-impulse characterization of critical pulse loads in structural dynamics

    International Nuclear Information System (INIS)

    Abrahamson, G.R.; Lindberg, H.E.

    1975-01-01

    In presenting the characterization scheme, some general features are described first. A detailed analysis is given for the rigid-plastic system of one degree of freedom to illustrate the calculation of critical load curves in terms of peak load and impulse. This is followed by the presentation of critical load curves for uniformly loaded rigid-plastic beams and plates and for dynamic buckling of cylindrical shells under uniform lateral loads. The peak load-impulse characterization of critical pulse loads is compared with the dynamic load factor characterization, and some aspects of the history of the peak load-pulse scheme are presented. (orig./HP) [de

  16. A deterministic, gigabit serial timing, synchronization and data link for the RHIC LLRF

    International Nuclear Information System (INIS)

    Hayes, T.; Smith, K.S.; Severino, F.

    2011-01-01

    A critical capability of the new RHIC low level rf (LLRF) system is the ability to synchronize signals across multiple locations. The 'Update Link' provides this functionality. The 'Update Link' is a deterministic serial data link based on the Xilinx RocketIO protocol that is broadcast over fiber optic cable at 1 gigabit per second (Gbps). The link provides timing events and data packets as well as time stamp information for synchronizing diagnostic data from multiple sources. The new RHIC LLRF was designed to be a flexible, modular system. The system is constructed of numerous independent RF Controller chassis. To provide synchronization among all of these chassis, the Update Link system was designed. The Update Link system provides a low latency, deterministic data path to broadcast information to all receivers in the system. The Update Link system is based on a central hub, the Update Link Master (ULM), which generates the data stream that is distributed via fiber optic links. Downstream chassis have non-deterministic connections back to the ULM that allow any chassis to provide data that is broadcast globally.

  17. Prediction of future nitrogen loading to Lake Rotorua

    International Nuclear Information System (INIS)

    Morgenstern, U.; Gordon, D.

    2006-01-01

    loading estimate for the direct groundwater has the largest uncertainty because very limited age and chemistry data is available. Lake side springs and minor streams together contribute only about 5% of the total nitrogen load to Lake Rotorua. Hamurana, Awahou and Waingaehe streams are expected to show the largest increases in N loading in the future because they contain the oldest water, and Hamurana and Awahou streams will have the largest increase in nitrogen mass loading because they have the largest flow. Utuhina, Waiteti, and Puarenga streams are expected to have medium increases in nitrogen loading because of younger water age and lower flow. Ngongotaha, Waiohewa, and Waiowhiro streams are expected to have little further increase in N loading because of low flow or steady-state already reached. Landuse intensification that has occurred within the last 20 years is not yet reflected in the current nitrogen prediction model because information on the timing and amount of intensification was not yet available. The present nitrogen prediction model assumes that the nitrogen input in the catchment from landuse development has remained relatively constant since the 1950's. The current predictions would therefore represent a lower limit to which the more recent nitrogen loads would have to be added. If more information on timing and amount of landuse changes becomes available, the N load predictions can be refined to incorporate landuse change in several stages by calculating the predicted N load for each stage and adding these. Positive (intensification) or negative (retirement) changes can be considered. The large groundwater system of the Lake Rotorua catchment responds delayed by decades to landuse changes. These timeframes will need to be considered carefully for any possible mitigation options in the catchment. (author). 8 refs., 14 figs., 2 tabs

  18. Linking the Tao, biomathics and information through the logic of energy.

    Science.gov (United States)

    Brenner, Joseph E

    2017-12-01

    The knowledge accumulated in West and East is incomplete in different ways. The mainstream Western approach has contributed the basis for modern science, but indications have appeared in the Western literature that something has been missing in it that Eastern thought could offer. This paper explores the similarities and differences between Eastern and Western approaches to knowledge and whether a trend exists toward their conjunction or convergence. I suggest that a process of conjunction of these different modes of exploration of what the concepts of 'Life and Mind' really entail, at the interface of philosophy and science, is taking place in the areas of information and biomathics. These conjunctions in China and in the West are characterized by scientific and philosophical systems which are holistic rather than reductionist. I argue that a non-standard, non-truth-functional logic of energy, based on the work of Stéphane Lupasco (1900-1988), provides a thread linking these approaches. Grounded in modern physics, it can describe the qualitative changes which are the focus of Chinese thought. In biology, Lupasco showed how the principles of this logic of dynamic relations operate in intra- and inter-cellular processes and at higher levels of organization. This paper supports key, primarily Chinese concepts and critiques the logical and categorial distinctions underlying and restricting the Western world-view. The paper also supports the implicit openness of Integral Biomathics to qualitative Eastern perspectives. Its finality is to find, from the conjunction, "better ideas for better exploration" of the nature of mind and life. This is not an academic exercise but a moral imperative for both Eastern and Western society. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. A novel method for decomposing electricity feeder load into elementary profiles from customer information

    International Nuclear Information System (INIS)

    Gerossier, Alexis; Barbier, Thibaut; Girard, Robin

    2017-01-01

    Highlights: •Use of aggregated electricity load profiles and customer description at feeder level. •Statistical recovery of elementary load profiles with customer categorization. •Generation of load demand profiles for unknown feeders and new local areas. •Relevancy of the different categorizations. -- Abstract: To plan a distribution grid involves making a long-term forecast of sub-hourly demand, which requires modeling the demand and its dynamics with aggregated measurement data. Distribution system operators (DSOs) have been recording electricity sub-hourly demand delivered by their medium-voltage feeders (around 1000—10,000 customers) for several years. Demand profiles differ widely among the various considered feeders. This is partly due to the varying mix of customer categories from one feeder to another. To overcome this issue, elementary demand profiles are often associated with customer categories and then combined according to a mix description. This paper presents a novel method to estimate elementary profiles that only requires several feeder demand curves and a description of customers. The method relies on a statistical blind source model and a new estimation procedure based on the augmented Lagrangian method. The use of feeders to estimate elementary profiles means that measurements are fully representative and continuously updated. We illustrate the proposed method through a case study comprising around 1000 feeder demand curves operated by the main French DSO Enedis. We propose an application o that uses the obtained profiles to evaluate the contribution of any set of new customers to a feeder peak load. We show that profiles enable a simulation of new unmeasured areas with errors of around 20%. We also show how our method can be used to evaluate the relevancy of different customer categorizations.

  20. Programming Algorithms of load balancing with HA-Proxy in HTTP services

    Directory of Open Access Journals (Sweden)

    José Teodoro Mejía Viteri

    2018-02-01

    Full Text Available The access to the public and private services through the web gains daily protagonism, and sometimes they must support amounts of requests that a team can not process, so there are solutions that use algorithms that allow to distribute the load of requests of a web application in several equipment; the objective of this work is to perform an analysis of load balancing scheduling algorithms through the HA-Proxy tool, and deliver an instrument that identifies the load distribution algorithm to be used and the technological infrastructure, to largely cover implementation. The information used for this work is based on a bibliographic analysis, eld study and implementation of the different load balancing algorithms in equipment, where the distribution and its performance will be analyzed. The incorporation of this technology to the management of services on the web, improves availability, helps business continuity and through the different forms of distribution of the requests of the algorithms that can be implemented in HA-Proxy to provide those responsible for information technology systems with a view of their advantages and disadvantages.

  1. A class-based link prediction using Distance Dependent Chinese Restaurant Process

    Science.gov (United States)

    Andalib, Azam; Babamir, Seyed Morteza

    2016-08-01

    One of the important tasks in relational data analysis is link prediction which has been successfully applied on many applications such as bioinformatics, information retrieval, etc. The link prediction is defined as predicting the existence or absence of edges between nodes of a network. In this paper, we propose a novel method for link prediction based on Distance Dependent Chinese Restaurant Process (DDCRP) model which enables us to utilize the information of the topological structure of the network such as shortest path and connectivity of the nodes. We also propose a new Gibbs sampling algorithm for computing the posterior distribution of the hidden variables based on the training data. Experimental results on three real-world datasets show the superiority of the proposed method over other probabilistic models for link prediction problem.

  2. Analysis of dc-Link Voltage Switching Ripple in Three-Phase PWM Inverters

    Directory of Open Access Journals (Sweden)

    Marija Vujacic

    2018-02-01

    Full Text Available The three-phase voltage source inverter (VSI is de facto standard in power conversion systems. To realize high power density systems, one of the items to be correctly addressed is the design and selection of the dc-link capacitor in relation to the voltage switching ripple. In this paper, effective formulas for designing the dc-link capacitor as a function of the switching voltage ripple amplitude are obtained, considering the operating conditions such as the modulation index and the output current amplitude. The calculations are obtained considering the requirements and restrictions referring to the high (switching-frequency dc-link voltage ripple component. Analyses have been performed considering the dc source impedance (non-ideal dc voltage source at the switching frequency and a balanced load. Analytical expressions are derived for the dc-link voltage switching ripple amplitude and its maximum value over the fundamental period. Different values of modulation index and output phase angle have been considered and different diagrams are presented. Analytical results were validated both by simulations and comprehensive experimental tests.

  3. Working memory load improves early stages of independent visual processing

    OpenAIRE

    Cocchi, Luca; Toepel, Ulrike; De Lucia, Marzia; Martuzzi, Roberto; Wood, Stephen J.; Carter, Olivia; Murray, Micah M.

    2010-01-01

    Increasing evidence suggests that working memory and perceptual processes are dynamically interrelated due to modulating activity in overlapping brain networks. However, the direct influence of working memory on the spatio-temporal brain dynamics of behaviorally relevant intervening information remains unclear. To investigate this issue, subjects performed a visual proximity grid perception task under three different visual-spatial working memory (VSWM) load conditions. VSWM load was manipula...

  4. System and method employing a minimum distance and a load feature database to identify electric load types of different electric loads

    Science.gov (United States)

    Lu, Bin; Yang, Yi; Sharma, Santosh K; Zambare, Prachi; Madane, Mayura A

    2014-12-23

    A method identifies electric load types of a plurality of different electric loads. The method includes providing a load feature database of a plurality of different electric load types, each of the different electric load types including a first load feature vector having at least four different load features; sensing a voltage signal and a current signal for each of the different electric loads; determining a second load feature vector comprising at least four different load features from the sensed voltage signal and the sensed current signal for a corresponding one of the different electric loads; and identifying by a processor one of the different electric load types by determining a minimum distance of the second load feature vector to the first load feature vector of the different electric load types of the load feature database.

  5. Relationship Between Pretraining Subjective Wellness Measures, Player Load, and Rating-of-Perceived-Exertion Training Load in American College Football.

    Science.gov (United States)

    Govus, Andrew D; Coutts, Aaron; Duffield, Rob; Murray, Andrew; Fullagar, Hugh

    2018-01-01

    The relationship between pretraining subjective wellness and external and internal training load in American college football is unclear. To examine the relationship of pretraining subjective wellness (sleep quality, muscle soreness, energy, wellness Z score) with player load and session rating of perceived exertion (s-RPE-TL) in American college football players. Subjective wellness (measured using 5-point, Likert-scale questionnaires), external load (derived from GPS and accelerometry), and s-RPE-TL were collected during 3 typical training sessions per week for the second half of an American college football season (8 wk). The relationship of pretraining subjective wellness with player load and s-RPE training load was analyzed using linear mixed models with a random intercept for athlete and a random slope for training session. Standardized mean differences (SMDs) denote the effect magnitude. A 1-unit increase in wellness Z score and energy was associated with trivial 2.3% (90% confidence interval [CI] 0.5, 4.2; SMD 0.12) and 2.6% (90% CI 0.1, 5.2; SMD 0.13) increases in player load, respectively. A 1-unit increase in muscle soreness (players felt less sore) corresponded to a trivial 4.4% (90% CI -8.4, -0.3; SMD -0.05) decrease in s-RPE training load. Measuring pretraining subjective wellness may provide information about players' capacity to perform in a training session and could be a key determinant of their response to the imposed training demands American college football. Hence, monitoring subjective wellness may aid in the individualization of training prescription in American college football players.

  6. Information on the Run: Experiencing Information during an Ultramarathon

    Science.gov (United States)

    Gorichanaz, Tim

    2015-01-01

    Introduction: Ultrarunning is an individual sport and serious leisure pursuit that requires ongoing information access and use during events, but has not yet been studied in information research. This study leverages a link between the theory of life in the round and the serious leisure perspective to explore the information experience of an…

  7. Exercise-induced bone formation is poorly linked to local strain magnitude in the sheep tibia.

    Directory of Open Access Journals (Sweden)

    Ian J Wallace

    Full Text Available Functional interpretations of limb bone structure frequently assume that diaphyses adjust their shape by adding bone primarily across the plane in which they are habitually loaded in order to minimize loading-induced strains. Here, to test this hypothesis, we characterize the in vivo strain environment of the sheep tibial midshaft during treadmill exercise and examine whether this activity promotes bone formation disproportionately in the direction of loading in diaphyseal regions that experience the highest strains. It is shown that during treadmill exercise, sheep tibiae were bent in an anteroposterior direction, generating maximal tensile and compressive strains on the anterior and posterior shaft surfaces, respectively. Exercise led to significantly increased periosteal bone formation; however, rather than being biased toward areas of maximal strains across the anteroposterior axis, exercise-related osteogenesis occurred primarily around the medial half of the shaft circumference, in both high and low strain regions. Overall, the results of this study demonstrate that loading-induced bone growth is not closely linked to local strain magnitude in every instance. Therefore, caution is necessary when bone shaft shape is used to infer functional loading history in the absence of in vivo data on how bones are loaded and how they actually respond to loading.

  8. Hybrid Multidimensional Relational and Link Analytical Knowledge Discovery for Law Enforcement

    Energy Technology Data Exchange (ETDEWEB)

    Joslyn, Cliff A.; Gillen, David S.; Burke, John S.; Critchlow, Terence J.; Damante, Matt; Fernandes, Robert

    2008-08-01

    The challenges facing the Department of Homeland Security (DHS) require not only multi-dimensional, but also multi-scale data analysis. In particular, the ability to seamlessly move from summary information, such as trends, into detailed analysis of individual entities, while critical for law enforcement, typically requires manually transferring information among multiple tools. Such time-consuming and error prone processes significantly hamper the analysts' ability to quickly explore data and identify threats. As part of a DHS Science and Technology effort, we have been developing and deploying for Immigration and Customs Enforcement the CubeLink system integrating information between relational data cubes and link analytical semantic graphs. In this paper we describe CubeLink in terms of the underlying components, their integration, and the formal mapping from multidimensional data analysis into link analysis. In so doing, we provide a formal basis for one particular form of automatic schema-ontology mapping from OLAP data cubes to semantic graphs databases, and point the way towards future ``intelligent'' OLAP data cubes equipped with meta-data about their dimensional typing.

  9. Growth of pine ecosystems as a function of climate and pollution load. A regional case study; Wachstum von Kiefern-Oekosystemen in Abhaengigkeit von Klima und Stoffeintrag. Eine regionale Fallstudie auf Landschaftsebene

    Energy Technology Data Exchange (ETDEWEB)

    Erhard, M.

    1999-12-01

    An analysis on landscape level was performed to investigate the growth of Scots pine stands (Pinus sylvestris L.) in the research area of 'Duebener Heide' under the impact of rapidly changing pollution loads and to evaluate their further development. Central to the work was a spatial database, installed using a geographic information system (GIS). This database enabled the statistical analysis of relationships and correlations between the growth of the pine stands, the influence of pollution impacts and the natural site characteristics. The results of emission and immission modelling gave detailed evaluation of the pollution load over the investigated area. The spatial information database was linked with a process-based growth model called FORSANA. The resulting regional model was used to simulate forest growth on stand level for variable time periods. The plausibility of the simulation results of the model was checked for the influence of different patterns of pollution using the data available for the investigated area. Simulation runs were also made with these data to estimate the further development of the pine stand under various climate and emission scenarios. (orig.)

  10. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... in the spread of HIV infection in the United States. Drugs can change the way the brain works, disrupting the parts of the brain that people use to weigh risks and benefits when making decisions. This page connects you to information about the link between drug misuse and HIV ...

  11. Load-release of small and macromolecules from elastomers with reversible gyroid mesoporosity

    DEFF Research Database (Denmark)

    Guo, Fengxiao; Schulte, Lars; Ndoni, Sokol

    2012-01-01

    . However, in the gel state in the presence of a good solvent the swollen matrix did show a nanoporous structure originated from the gyroid block copolymer precursor. Nanopores can be opened or closed depending on the presence or absence of a solvent. Macromolecules like PEG of different molecular weights......A collapsed elastomeric matrix of lightly cross-linked 1,2-polybutadiene (1,2-PB) was prepared from a self-assembled 1,2-polybutadiene-b- polydimethylsiloxane (1,2-PB-b-PDMS) of gyroid morphology after the removal of the PDMS block. No mesoporosity could be observed in the material in the dry state...... or small molecules like the surfactant SDS were loaded into the opened nanoporous matrix in the presence of a solvent and remained trapped. The loaded molecules could be released again in the presence of a solvent. The load and release of the molecules in deuterated form were monitored by in situ time...

  12. System and method employing a self-organizing map load feature database to identify electric load types of different electric loads

    Science.gov (United States)

    Lu, Bin; Harley, Ronald G.; Du, Liang; Yang, Yi; Sharma, Santosh K.; Zambare, Prachi; Madane, Mayura A.

    2014-06-17

    A method identifies electric load types of a plurality of different electric loads. The method includes providing a self-organizing map load feature database of a plurality of different electric load types and a plurality of neurons, each of the load types corresponding to a number of the neurons; employing a weight vector for each of the neurons; sensing a voltage signal and a current signal for each of the loads; determining a load feature vector including at least four different load features from the sensed voltage signal and the sensed current signal for a corresponding one of the loads; and identifying by a processor one of the load types by relating the load feature vector to the neurons of the database by identifying the weight vector of one of the neurons corresponding to the one of the load types that is a minimal distance to the load feature vector.

  13. Assessing and Reducing Miscellaneous Electric Loads (MELs) in Banks

    Energy Technology Data Exchange (ETDEWEB)

    Rauch, Emily M.

    2012-09-01

    Miscellaneous electric loads (MELs) are loads outside of a building's core functions of heating, ventilating, air conditioning, lighting, and water heating. MELs are a large percentage of total building energy loads. This report reviews methods for reducing MELs in Banks. Reducing MELs in a bank setting requires both local and corporate action. Corporate action centers on activities to prioritize and allocate the right resources to correct procurement and central control issues. Local action includes branch assessment or audits to identify specific loads and needs. The worksheet at the end of this guide can help with cataloging needed information and estimating savings potential. The following steps provide a guide to MEL reductions in Bank Branches. The general process has been adapted from a process developed for office buildings the National Renewable Energy Laboratory (NREL, 2011).

  14. Monitoring external and internal loads of brazilian soccer referees during official matches.

    Science.gov (United States)

    Costa, Eduardo C; Vieira, Caio M A; Moreira, Alexandre; Ugrinowitsch, Carlos; Castagna, Carlo; Aoki, Marcelo S

    2013-01-01

    This study aimed to assess the external and internal loads of Brazilian soccer referees during official matches. A total of 11 field referees (aged 36.2 ± 7.5 years) were monitored during 35 matches. The external (distance covered, mean and maximal speed) and internal load parameters (session ratings of perceived exertion [RPE] training load [TL], Edwards' TL, and time spent in different heart rate [HR] zones) were assessed in 3-4 matches per referee. External load parameters were measured using a wrist Global Positioning System (GPS) receiver. No differences in distance covered (5.219 ± 205 vs. 5.230 ± 237 m) and maximal speed (19.3 ± 1.0 vs. 19.4 ± 1.4 km·h(-1)) were observed between the halves of the matches (p > 0.05). However, the mean speed was higher in the first half of the matches (6.6 ± 0.4 vs. 6.4 ± 0.3 km·h(-1)) (p external and internal load demands during official matches. The portable GPS/HR monitors and session RPE method can provide relevant information regarding the magnitude of the physiological strain during official matches. Key PointsHigh external and internal loads were imposed on Brazilian soccer referees during official matches.There was a high positive correlation between a subjective marker of internal load (session RPE) and parameters of external load (distance covered between 90-100% of HRmax and maximal speed).There was a high positive correlation between session RPE method and Edwards' method.Session RPE seems to be a reliable marker of internal load.The portable GPS/HR monitors and the session RPE method can provide relevant information regarding the magnitude of external and internal loads of soccer referees during official matches.

  15. New approaches to provide ride-through for critical loads in electric power distribution systems

    Science.gov (United States)

    Montero-Hernandez, Oscar C.

    2001-07-01

    The extensive use of electronic circuits has enabled modernization, automation, miniaturization, high quality, low cost, and other achievements regarding electric loads in the last decades. However, modern electronic circuits and systems are extremely sensitive to disturbances from the electric power supply. In fact, the rate at which these disturbances happen is considerable as has been documented in recent years. In response to the power quality concerns presented previously, this dissertation is proposing new approaches to provide ride-through for critical loads during voltage disturbances with emphasis on voltage sags. In this dissertation, a new approach based on an AC-DC-AC system is proposed to provide ride-through for critical loads connected in buildings and/or an industrial system. In this approach, a three-phase IGBT inverter with a built in Dc-link voltage regulator is suitably controlled along with static by-pass switches to provide continuous power to critical loads. During a disturbance, the input utility source is disconnected and the power from the inverter is connected to the load. The remaining voltage in the AC supply is converted to DC and compensated before being applied to the inverter and the load. After detecting normal utility conditions, power from the utility is restored to the critical load. In order to achieve an extended ride-through capability a second approach is introduced. In this case, the Dc-link voltage regulator is performed by a DC-DC Buck-Boost converter. This new approach has the capability to mitigate voltage variations below and above the nominal value. In the third approach presented in this dissertation, a three-phase AC to AC boost converter is investigated. This converter provides a boosting action for the utility input voltages, right before they are applied to the load. The proposed Pulse Width Modulation (PWM) control strategy ensures independent control of each phase and compensates for both single-phase or poly

  16. When Information Improves Information Security

    Science.gov (United States)

    Grossklags, Jens; Johnson, Benjamin; Christin, Nicolas

    This paper presents a formal, quantitative evaluation of the impact of bounded-rational security decision-making subject to limited information and externalities. We investigate a mixed economy of an individual rational expert and several naïve near-sighted agents. We further model three canonical types of negative externalities (weakest-link, best shot and total effort), and study the impact of two information regimes on the threat level agents are facing.

  17. Demand Response Load Following of Source and Load Systems

    DEFF Research Database (Denmark)

    Hu, Jianqiang; Cao, Jinde; Yong, Taiyou

    2017-01-01

    This paper presents a demand response load following strategy for an interconnected source and load system, in which we utilize traditional units and population of cooling thermostatically controlled loads (TCLs) to follow the mismatched power caused by the load activities and the renewable power...... injection in real time. In the demand side of power systems, these TCLs are often affiliated to a bus load agent and can be aggregated to multiple TCL aggregators. Firstly, aggregate evaluation of the TCL aggregator is carried out based on a bilinear aggregate model so as to derive the available regulation...

  18. LOAD THAT MAXIMIZES POWER OUTPUT IN COUNTERMOVEMENT JUMP

    Directory of Open Access Journals (Sweden)

    Pedro Jimenez-Reyes

    2016-02-01

    Full Text Available ABSTRACT Introduction: One of the main problems faced by strength and conditioning coaches is the issue of how to objectively quantify and monitor the actual training load undertaken by athletes in order to maximize performance. It is well known that performance of explosive sports activities is largely determined by mechanical power. Objective: This study analysed the height at which maximal power output is generated and the corresponding load with which is achieved in a group of male-trained track and field athletes in the test of countermovement jump (CMJ with extra loads (CMJEL. Methods: Fifty national level male athletes in sprinting and jumping performed a CMJ test with increasing loads up to a height of 16 cm. The relative load that maximized the mechanical power output (Pmax was determined using a force platform and lineal encoder synchronization and estimating the power by peak power, average power and flight time in CMJ. Results: The load at which the power output no longer existed was at a height of 19.9 ± 2.35, referring to a 99.1 ± 1% of the maximum power output. The load that maximizes power output in all cases has been the load with which an athlete jump a height of approximately 20 cm. Conclusion: These results highlight the importance of considering the height achieved in CMJ with extra load instead of power because maximum power is always attained with the same height. We advise for the preferential use of the height achieved in CMJEL test, since it seems to be a valid indicative of an individual's actual neuromuscular potential providing a valid information for coaches and trainers when assessing the performance status of our athletes and to quantify and monitor training loads, measuring only the height of the jump in the exercise of CMJEL.

  19. Load Forecasting in Electric Utility Integrated Resource Planning

    Energy Technology Data Exchange (ETDEWEB)

    Carvallo, Juan Pablo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Larsen, Peter H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sanstad, Alan H [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Goldman, Charles A. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-07-19

    Integrated resource planning (IRP) is a process used by many vertically-integrated U.S. electric utilities to determine least-cost/risk supply and demand-side resources that meet government policy objectives and future obligations to customers and, in many cases, shareholders. Forecasts of energy and peak demand are a critical component of the IRP process. There have been few, if any, quantitative studies of IRP long-run (planning horizons of two decades) load forecast performance and its relationship to resource planning and actual procurement decisions. In this paper, we evaluate load forecasting methods, assumptions, and outcomes for 12 Western U.S. utilities by examining and comparing plans filed in the early 2000s against recent plans, up to year 2014. We find a convergence in the methods and data sources used. We also find that forecasts in more recent IRPs generally took account of new information, but that there continued to be a systematic over-estimation of load growth rates during the period studied. We compare planned and procured resource expansion against customer load and year-to-year load growth rates, but do not find a direct relationship. Load sensitivities performed in resource plans do not appear to be related to later procurement strategies even in the presence of large forecast errors. These findings suggest that resource procurement decisions may be driven by other factors than customer load growth. Our results have important implications for the integrated resource planning process, namely that load forecast accuracy may not be as important for resource procurement as is generally believed, that load forecast sensitivities could be used to improve the procurement process, and that management of load uncertainty should be prioritized over more complex forecasting techniques.

  20. Cognitive Load Theory: How Many Types of Load Does It Really Need?

    Science.gov (United States)

    Kalyuga, Slava

    2011-01-01

    Cognitive load theory has been traditionally described as involving three separate and additive types of load. Germane load is considered as a learning-relevant load complementing extraneous and intrinsic load. This article argues that, in its traditional treatment, germane load is essentially indistinguishable from intrinsic load, and therefore…

  1. Gender-Specific Effects of Cognitive Load on Social Discounting.

    Science.gov (United States)

    Strombach, Tina; Margittai, Zsofia; Gorczyca, Barbara; Kalenscher, Tobias

    2016-01-01

    We live busy, social lives, and meeting the challenges of our complex environments puts strain on our cognitive systems. However, cognitive resources are limited. It is unclear how cognitive load affects social decision making. Previous findings on the effects of cognitive load on other-regarding preferences have been ambiguous, allowing no coherent opinion whether cognitive load increases, decreases or does not affect prosocial considerations. Here, we suggest that social distance between individuals modulates whether generosity towards a recipient increases or decreases under cognitive load conditions. Participants played a financial social discounting task with several recipients at variable social distance levels. In this task, they could choose between generous alternatives, yielding medium financial rewards for the participant and recipient at variable social distances, or between a selfish alternative, yielding larger rewards for the participant alone. We show that the social discount function of male participants was significantly flattened under high cognitive load conditions, suggesting they distinguished less between socially close and socially distant recipients. Unexpectedly, the cognitive-load effect on social discounting was gender-specific: while social discounting was strongly dependent on cognitive load in men, women were nearly unaffected by cognitive load manipulations. We suggest that cognitive load leads men, but not women to simplify the decision problem by neglecting the social distance information. We consider our study a good starting point for further experiments exploring the role of gender in prosocial choice.

  2. Integration of wind power in Germany's transmission grid by using HVDC links

    Energy Technology Data Exchange (ETDEWEB)

    Wasserrab, Andreas; Fleckenstein, Marco; Balzer, Gerd [Technische Univ. Darmstadt (Germany). Inst. of Electrical Power and Energy

    2012-07-01

    This paper deals with the challenges for the integration of wind power in Germany's transmission grid. Several options for the expansion of transmission grids are discussed. The consideration focuses on HVDC technologies, which are used for further analyses. The basis of the analysis is the transmission grid of a German transmission system operator, which is implemented in a simulation tool. The model consists of the 110-kV-, 220-kV- and the 380-kV-system. In different scenarios the integration of wind power is analysed by applying HVDC links to connect the northern part of the grid with the load centres in the South. The results of load flow calculations are discussed focusing on transmission line loading and voltage stability. The paper concludes with future prospects of HVDC applications in Germany. (orig.)

  3. Foot loading characteristics during three fencing-specific movements.

    Science.gov (United States)

    Trautmann, Caroline; Martinelli, Nicolo; Rosenbaum, Dieter

    2011-12-01

    Plantar pressure characteristics during fencing movements may provide more specific information about the influence of foot loading on overload injury patterns. Twenty-nine experienced fencers participated in the study. Three fencing-specific movements (lunge, advance, retreat) and normal running were performed with three different shoe models: Ballestra (Nike, USA), Adistar Fencing Lo (Adidas, Germany), and the fencers' own shoes. The Pedar system (Novel, Munich, Germany) was used to collect plantar pressures at 50 Hz. Peak pressures, force-time integrals and contact times for five foot regions were compared between four athletic tasks in the lunge leg and supporting leg. Plantar pressure analysis revealed characteristic pressure distribution patterns for the fencing movements. For the lunge leg, during the lunge and advance movements the heel is predominantly loaded; during retreat, it is the hallux. For the supporting leg, during the lunge and advance movements the forefoot is predominantly loaded; during retreat, it is the hallux. Fencing-specific movements load the plantar surface in a distinct way compared with running. An effective cushioning in the heel and hallux region would help to minimize foot loading during fencing-specific movements.

  4. Open Informational Ecosystems: The Missing Link for Sharing Educational Resources

    Directory of Open Access Journals (Sweden)

    Michael Kerres

    2015-02-01

    Full Text Available Open educational resources are not available “as such”. Their provision relies on a technological infrastructure of related services that can be described as an informational ecosystem. A closed informational ecosystem keeps educational resources within its boundary. An open informational ecosystem relies on the concurrence of independent stakeholders that jointly provide (meta- information also beyond its boundaries. Mechanisms of open informational ecosystems are described and how they contribute to the delivery of educational resources and to opening education. The paper describes the case of the German Bildungsserver that aims at establishing a federated network of providers of open and closed educational resources. It points out that the design of (inter-national informational ecosystems has a major influence on the future of open educational resources in education.

  5. Multi-link faults localization and restoration based on fuzzy fault set for dynamic optical networks.

    Science.gov (United States)

    Zhao, Yongli; Li, Xin; Li, Huadong; Wang, Xinbo; Zhang, Jie; Huang, Shanguo

    2013-01-28

    Based on a distributed method of bit-error-rate (BER) monitoring, a novel multi-link faults restoration algorithm is proposed for dynamic optical networks. The concept of fuzzy fault set (FFS) is first introduced for multi-link faults localization, which includes all possible optical equipment or fiber links with a membership describing the possibility of faults. Such a set is characterized by a membership function which assigns each object a grade of membership ranging from zero to one. OSPF protocol extension is designed for the BER information flooding in the network. The BER information can be correlated to link faults through FFS. Based on the BER information and FFS, multi-link faults localization mechanism and restoration algorithm are implemented and experimentally demonstrated on a GMPLS enabled optical network testbed with 40 wavelengths in each fiber link. Experimental results show that the novel localization mechanism has better performance compared with the extended limited perimeter vector matching (LVM) protocol and the restoration algorithm can improve the restoration success rate under multi-link faults scenario.

  6. The NINO [No Inspector, No Operator system] cask-loading safeguards system

    International Nuclear Information System (INIS)

    Fiarman, S.

    1987-01-01

    It is, in general difficult to determine by means of camera-surveillance techniques what is loaded into spent-fuel casks being prepared for shipment from light-water reactors to other reactors, reprocessing facilities, or long-term storage. Furthermore, the expected high frequency of cask loadings in the coming years would place too great a burden on the IAEA and Euratom inspectorates if each had to be observed by an inspector. For the case of shipment to other reactors and reprocessing facilities, the casks are soon opened and, in principle, their contents could be ascertained by direct inspection. In the case of long-term-storage facilities, the casks would stay sealed for years, thereby requiring the IAEA to know positively how many spent-fuel assemblies were loaded at the reactor and to have a continuity of knowledge of the cask's contents. It has been proposed instead that the facility operator place the cask seal on the cask within the field of view of a surveillance system linked to the cask seal. This solution, however, may not provide enough credibility for acceptance by the safeguards community. This paper presents an alternative to both inspector presence at cask loading and operator assistance in applying seals; this alternative is called the No Inspector, No Operator system (NINO)

  7. Cognitive Load Measurement in a Virtual Reality-based Driving System for Autism Intervention.

    Science.gov (United States)

    Zhang, Lian; Wade, Joshua; Bian, Dayi; Fan, Jing; Swanson, Amy; Weitlauf, Amy; Warren, Zachary; Sarkar, Nilanjan

    2017-01-01

    Autism Spectrum Disorder (ASD) is a highly prevalent neurodevelopmental disorder with enormous individual and social cost. In this paper, a novel virtual reality (VR)-based driving system was introduced to teach driving skills to adolescents with ASD. This driving system is capable of gathering eye gaze, electroencephalography, and peripheral physiology data in addition to driving performance data. The objective of this paper is to fuse multimodal information to measure cognitive load during driving such that driving tasks can be individualized for optimal skill learning. Individualization of ASD intervention is an important criterion due to the spectrum nature of the disorder. Twenty adolescents with ASD participated in our study and the data collected were used for systematic feature extraction and classification of cognitive loads based on five well-known machine learning methods. Subsequently, three information fusion schemes-feature level fusion, decision level fusion and hybrid level fusion-were explored. Results indicate that multimodal information fusion can be used to measure cognitive load with high accuracy. Such a mechanism is essential since it will allow individualization of driving skill training based on cognitive load, which will facilitate acceptance of this driving system for clinical use and eventual commercialization.

  8. Cognitive Load Measurement in a Virtual Reality-based Driving System for Autism Intervention

    Science.gov (United States)

    Zhang, Lian; Wade, Joshua; Bian, Dayi; Fan, Jing; Swanson, Amy; Weitlauf, Amy; Warren, Zachary; Sarkar, Nilanjan

    2016-01-01

    Autism Spectrum Disorder (ASD) is a highly prevalent neurodevelopmental disorder with enormous individual and social cost. In this paper, a novel virtual reality (VR)-based driving system was introduced to teach driving skills to adolescents with ASD. This driving system is capable of gathering eye gaze, electroencephalography, and peripheral physiology data in addition to driving performance data. The objective of this paper is to fuse multimodal information to measure cognitive load during driving such that driving tasks can be individualized for optimal skill learning. Individualization of ASD intervention is an important criterion due to the spectrum nature of the disorder. Twenty adolescents with ASD participated in our study and the data collected were used for systematic feature extraction and classification of cognitive loads based on five well-known machine learning methods. Subsequently, three information fusion schemes—feature level fusion, decision level fusion and hybrid level fusion—were explored. Results indicate that multimodal information fusion can be used to measure cognitive load with high accuracy. Such a mechanism is essential since it will allow individualization of driving skill training based on cognitive load, which will facilitate acceptance of this driving system for clinical use and eventual commercialization. PMID:28966730

  9. Dynamical load factor of impact loaded shell structures

    International Nuclear Information System (INIS)

    Hammel, J.

    1977-01-01

    Dynamical loaded structures can be analysed by spectral representations, which usually lead to an enormous computational effort. If it is possible to find a fitting dynamical load factor, the dynamical problem can be reduced to a statical one. The computation of this statical problem is much simpler. The disadvantage is that the dynamical load factor usually leads to a very rough approximation. In this paper it will be shown, that by combination of these two methods, the approximation of the dynamical load factor can be improved and the consumption of computation time can be enormously reduced. (Auth.)

  10. pH-controlled drug loading and release from biodegradable microcapsules.

    Science.gov (United States)

    Zhao, Qinghe; Li, Bingyun

    2008-12-01

    Microcapsules made of biopolymers are of both scientific and technological interest and have many potential applications in medicine, including their use as controlled drug delivery devices. The present study makes use of the electrostatic interaction between polycations and polyanions to form a multilayered microcapsule shell and also to control the loading and release of charged drug molecules inside the microcapsule. Micron-sized calcium carbonate (CaCO3) particles were synthesized and integrated with chondroitin sulfate (CS) through a reaction between sodium carbonate and calcium nitrate tetrahydrate solutions suspended with CS macromolecules. Oppositely charged biopolymers were alternately deposited onto the synthesized particles using electrostatic layer-by-layer self-assembly, and glutaraldehyde was introduced to cross-link the multilayered shell structure. Microcapsules integrated with CS inside the multilayered shells were obtained after decomposition of the CaCO3 templates. The integration of a matrix (i.e., CS) permitted the subsequent selective control of drug loading and release. The CS-integrated microcapsules were loaded with a model drug, bovine serum albumin labeled with fluorescein isothiocyanate (FITC-BSA), and it was shown that pH was an effective means of controlling the loading and release of FITC-BSA. Such CS-integrated microcapsules may be used for controlled localized drug delivery as biodegradable devices, which have advantages in reducing systemic side effects and increasing drug efficacy.

  11. Linking Biological Responses of Terrestrial N Eutrophication to the Final Ecosystem Goods and Services Classification System

    Science.gov (United States)

    Bell, M. D.; Clark, C.; Blett, T.

    2015-12-01

    The response of a biological indicator to N deposition can indicate that an ecosystem has surpassed a critical load and is at risk of significant change. The importance of this exceedance is often difficult to digest by policy makers and public audiences if the change is not linked to a familiar ecosystem endpoint. A workshop was held to bring together scientists, resource managers, and policy makers with expertise in ecosystem functioning, critical loads, and economics in an effort to identify the ecosystem services impacted by air pollution. This was completed within the framework of the Final Ecosystem Goods and Services (FEGS) Classification System to produce a product that identified distinct interactions between society and the effects of nitrogen pollution. From each change in a biological indicator, we created multiple ecological production functions to identify the cascading effects of the change to a measureable ecosystem service that a user interacts with either by enjoying, consuming, or appreciating the good or service, or using it as an input in the human economy. This FEGS metric was then linked to a beneficiary group that interacts with the service. Chains detailing the links from the biological indicator to the beneficiary group were created for aquatic and terrestrial acidification and eutrophication at the workshop, and here we present a subset of the workshop results by highlighting for 9 different ecosystems affected by terrestrial eutrophication. A total of 213 chains that linked to 37 unique FEGS metrics and impacted 15 beneficiary groups were identified based on nitrogen deposition mediated changes to biological indicators. The chains within each ecosystem were combined in flow charts to show the complex, overlapping relationships among biological indicators, ecosystem services, and beneficiary groups. Strength of relationship values were calculated for each chain based on support for the link in the scientific literature. We produced the

  12. Preventing information overload: cognitive load theory as an instructional framework for teaching pharmacology.

    Science.gov (United States)

    Kaylor, Sara K

    2014-02-01

    Nursing students are challenged by content-laden curricula and learning environments that emphasize testing outcomes. Likewise, educators are challenged to support student-centered learning in a manner that encourages students to connect and act upon their personal motivations. This article describes the use of cognitive load theory (CLT) as an instructional design framework for an undergraduate pharmacology for nursing course. Guided by the principles of CLT, four instructional strategies were used in this course: (a) opening review activities, (b) providing students with lecture notes, (c) a "Top Five" prototype approach, and (d) deciphering "Need to Knows" from "Nice to Knows." Instructional style and strategies received positive student feedback and were found to promote a student-centered environment and active learning. On the basis of this feedback, cognitive load theory may be a successful and effective framework for undergraduate pharmacology and other nursing courses, thus assisting students and educators alike in overcoming obstacles imposed on learning environments. Copyright 2014, SLACK Incorporated.

  13. Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

    DEFF Research Database (Denmark)

    Crestey, François; Ottesen, Lars Korsgaard; Jaroszewski, Jerzy Witold

    2008-01-01

    The Letter describes an improved, rapid and mild strategy for the loading of primary alcohols onto a polystyrene trityl resin via a highly reactive trityl bromide linker. This protocol facilitates an efficient resin loading even of acid-sensitive or heat-labile alcohols, which otherwise require...... expensive or non-commercial resin types. Secondary alcohols were only attached in moderate to low yields, while attempts to load a tertiary alcohol expectedly failed. Importantly, selective attachment of diols via a primary alcohol group in the presence of more hindered alcohol groups proved possible....... The effects of activation time and reagent excess as well as alcohol structure were investigated. This improved method provides a convenient access to O-linked resin-bound N-Fmoc-protected amino alcohols that may be employed in SPS of peptides with C-terminal alcohol functionalities. In the case...

  14. Electricity demand load forecasting of the Hellenic power system using an ARMA model

    Energy Technology Data Exchange (ETDEWEB)

    Pappas, S.Sp. [ASPETE - School of Pedagogical and Technological Education Department of Electrical Engineering Educators N. Heraklion, 141 21 Athens (Greece); Ekonomou, L.; Chatzarakis, G.E.; Skafidas, P.D. [ASPETE-School of Pedagogical and Technological Education, Department of Electrical Engineering Educators, N. Heraklion, 141 21 Athens (Greece); Karampelas, P. [Hellenic American University, IT Department, 12 Kaplanon Str., 106 80 Athens (Greece); Karamousantas, D.C. [Technological Educational Institute of Kalamata, Antikalamos, 24 100 Kalamata (Greece); Katsikas, S.K. [University of Piraeus, Department of Technology Education and Digital Systems, 150 Androutsou St., 18 532 Piraeus (Greece)

    2010-03-15

    Effective modeling and forecasting requires the efficient use of the information contained in the available data so that essential data properties can be extracted and projected into the future. As far as electricity demand load forecasting is concerned time series analysis has the advantage of being statistically adaptive to data characteristics compared to econometric methods which quite often are subject to errors and uncertainties in model specification and knowledge of causal variables. This paper presents a new method for electricity demand load forecasting using the multi-model partitioning theory and compares its performance with three other well established time series analysis techniques namely Corrected Akaike Information Criterion (AICC), Akaike's Information Criterion (AIC) and Schwarz's Bayesian Information Criterion (BIC). The suitability of the proposed method is illustrated through an application to actual electricity demand load of the Hellenic power system, proving the reliability and the effectiveness of the method and making clear its usefulness in the studies that concern electricity consumption and electricity prices forecasts. (author)

  15. A risk-informed evaluation of MOX fuel loading in PWRS

    International Nuclear Information System (INIS)

    Lyman, E.S.

    2001-01-01

    The full text follows: The U.S. Department of Energy (DOE) has signed a contract with Duke Cogema Stone and Webster (DCS) for fabrication of mixed-oxide (MOX) fuel and irradiation of the MOX fuel at the Catawba and McGuire pressurized-water reactors (PWRs), operated by Duke Power. The first load of MOX fuel is scheduled for 2007. In order to use MOX in these plants, Duke Power will have to apply to the Nuclear Regulatory Commission (NRC) for amendments to their operating licenses. Until recently, there have been no numerical guidelines for determining the acceptability of license amendment requests. However, such guidelines are now at hand with the adoption in 1998 of NRC Regulatory Guide 1.174, which defines a maximum value for the permissible increase in risk to the public resulting from a proposed change to a nuclear plant's licensing basis (LB). The substitution of MOX fuel for low-enriched uranium (LEU) fuel in LWRs will have an impact on risk to the public that will require regulatory evaluation. One of the major differences is that use of MOX will increase the inventories of plutonium and minor actinides in the reactor core, thereby increasing the source term for certain severe accidents, such as a core melt with early containment failure or a spent fuel pool drain-down. The goal of this paper is to quantitatively evaluate the increase in risk associated with the greater actinide source term in MOX-fueled reactors, and to compare this increase with RG 1.174 guidelines. Standard computer programs (SCALE and MACCS2) are used to estimate the increase in severe accident risk to the public associated with the DCS plan to use 40% cores of weapons-grade MOX fuel. These values are then compared to the RG 1.174 acceptance criteria, using publicly available risk information. Since RG 1.174 guidelines are based on the assumption that severe accident source terms are not affected by LB changes, the RG 1.174 formalism must be modified for this case. A similar

  16. Load management for refrigeration systems: Potentials and barriers

    Energy Technology Data Exchange (ETDEWEB)

    Grein, Arne, E-mail: a.grein@tu-berlin.de [University of Technology Berlin, Institute for Energy Technology, Department of Energy Systems, Einsteinufer 25 (TA8), 10587 Berlin (Germany); Pehnt, Martin [Institute for Energy and Environmental Research Heidelberg (ifeu), Wilckensstr. 3, 69120 Heidelberg (Germany)

    2011-09-15

    As a strategy to deal with the increasing intermittent input of renewable energy sources in Germany, the adaptation of power consumption is complementary to power-plant regulation, grid expansion and physical energy storage. One demand sector that promises strong returns for load management efforts is cooling and refrigeration. In these processes, thermal inertia provides a temporal buffer for shifting and adjusting the power consumption of cooling systems. We have conducted an empirical investigation to obtain a detailed and time-resolved bottom-up analysis of load management for refrigeration systems in the city of Mannheim, Germany. We have extrapolated our results to general conditions in Germany. Several barriers inhibit the rapid adoption of load management strategies for cooling systems, including informational barriers, strict compliance with legal cooling requirements, liability issues, lack of technical experience, an inadequate rate of return and organizational barriers. Small commercial applications of refrigeration in the food-retailing and cold storage in hotels and restaurants are particularly promising starting points for intelligent load management. When our results are applied to Germany, suitable sectors for load management have theoretical and achievable potential values of 4.2 and 2.8 GW, respectively, amounting to about 4-6% of the maximum power demand in Germany. - Highlights: > Potential and barriers for implementation of load shifting for refrigeration. > Empirical investigation for time-resolved bottom-up analysis in Mannheim, Germany. > Suitable sectors and further recommendations for introducing load management.> Extrapolation of results from local to national level.

  17. Load management for refrigeration systems: Potentials and barriers

    International Nuclear Information System (INIS)

    Grein, Arne; Pehnt, Martin

    2011-01-01

    As a strategy to deal with the increasing intermittent input of renewable energy sources in Germany, the adaptation of power consumption is complementary to power-plant regulation, grid expansion and physical energy storage. One demand sector that promises strong returns for load management efforts is cooling and refrigeration. In these processes, thermal inertia provides a temporal buffer for shifting and adjusting the power consumption of cooling systems. We have conducted an empirical investigation to obtain a detailed and time-resolved bottom-up analysis of load management for refrigeration systems in the city of Mannheim, Germany. We have extrapolated our results to general conditions in Germany. Several barriers inhibit the rapid adoption of load management strategies for cooling systems, including informational barriers, strict compliance with legal cooling requirements, liability issues, lack of technical experience, an inadequate rate of return and organizational barriers. Small commercial applications of refrigeration in the food-retailing and cold storage in hotels and restaurants are particularly promising starting points for intelligent load management. When our results are applied to Germany, suitable sectors for load management have theoretical and achievable potential values of 4.2 and 2.8 GW, respectively, amounting to about 4-6% of the maximum power demand in Germany. - Highlights: → Potential and barriers for implementation of load shifting for refrigeration. → Empirical investigation for time-resolved bottom-up analysis in Mannheim, Germany. → Suitable sectors and further recommendations for introducing load management.→ Extrapolation of results from local to national level.

  18. Research of Impact Load in Large Electrohydraulic Load Simulator

    Directory of Open Access Journals (Sweden)

    Yongguang Liu

    2014-01-01

    Full Text Available The stronger impact load will appear in the initial phase when the large electric cylinder is tested in the hardware-in-loop simulation. In this paper, the mathematical model is built based on AMESim, and then the reason of the impact load is investigated through analyzing the changing tendency of parameters in the simulation results. The inhibition methods of impact load are presented according to the structural invariability principle and applied to the actual system. The final experimental result indicates that the impact load is inhibited, which provides a good experimental condition for the electric cylinder and promotes the study of large load simulator.

  19. Stroop-like effects in a new-code learning task: A cognitive load theory perspective.

    Science.gov (United States)

    Hazan-Liran, Batel; Miller, Paul

    2017-09-01

    To determine whether and how learning is biased by competing task-irrelevant information that creates extraneous cognitive load, we assessed the efficiency of university students with a learning paradigm in two experiments. The paradigm asked participants to learn associations between eight words and eight digits. We manipulated congruity of the digits' ink colour with the words' semantics. In Experiment 1 word stimuli were colour words (e.g., blue, yellow) and in Experiment 2 colour-related word concepts (e.g., sky, banana). Marked benefits and costs on learning due to variation in extraneous cognitive load originating from processing task-irrelevant information were evident. Implications for cognitive load theory and schooling are discussed.

  20. How much is too much? (Part 2) International Olympic Committee consensus statement on load in sport and risk of illness.

    Science.gov (United States)

    Schwellnus, Martin; Soligard, Torbjørn; Alonso, Juan-Manuel; Bahr, Roald; Clarsen, Ben; Dijkstra, H Paul; Gabbett, Tim J; Gleeson, Michael; Hägglund, Martin; Hutchinson, Mark R; Janse Van Rensburg, Christa; Meeusen, Romain; Orchard, John W; Pluim, Babette M; Raftery, Martin; Budgett, Richard; Engebretsen, Lars

    2016-09-01

    The modern-day athlete participating in elite sports is exposed to high training loads and increasingly saturated competition calendar. Emerging evidence indicates that inappropriate load management is a significant risk factor for acute illness and the overtraining syndrome. The IOC convened an expert group to review the scientific evidence for the relationship of load-including rapid changes in training and competition load, competition calendar congestion, psychological load and travel-and health outcomes in sport. This paper summarises the results linking load to risk of illness and overtraining in athletes, and provides athletes, coaches and support staff with practical guidelines for appropriate load management to reduce the risk of illness and overtraining in sport. These include guidelines for prescription of training and competition load, as well as for monitoring of training, competition and psychological load, athlete well-being and illness. In the process, urgent research priorities were identified. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  1. Load research manual. Volume 2. Fundamentals of implementing load research procedures

    Energy Technology Data Exchange (ETDEWEB)

    Brandenburg, L.; Clarkson, G.; Grund, Jr., C.; Leo, J.; Asbury, J.; Brandon-Brown, F.; Derderian, H.; Mueller, R.; Swaroop, R.

    1980-11-01

    This three-volume manual presents technical guidelines for electric utility load research. Special attention is given to issues raised by the load data reporting requirements of the Public Utility Regulatory Policies Act of 1978 and to problems faced by smaller utilities that are initiating load research programs. In Volumes 1 and 2, procedures are suggested for determining data requirements for load research, establishing the size and customer composition of a load survey sample, selecting and using equipment to record customer electricity usage, processing data tapes from the recording equipment, and analyzing the data. Statistical techniques used in customer sampling are discussed in detail. The costs of load research also are estimated, and ongoing load research programs at three utilities are described. The manual includes guides to load research literature and glossaries of load research and statistical terms.

  2. Effect of ripple loads on sustained-load cracking in titanium alloys

    International Nuclear Information System (INIS)

    Pao, P.S.; Meyn, D.A.; Bayles, R.A.; Feng, C.R.; Yoder, G.R.

    1995-01-01

    In the present paper, the authors have extended their study on the effect of the ripple loads on the sustained-load cracking (SLC) behavior of two titanium alloys, Ti-6Al-4V (an α-β alloy) and Ti-15V-3Cr-3Al-3Sn (a β-α alloy), in an ambient air environment. The methodology which has been used successfully to treat ripple effects on stress-corrosion cracking (SCC) is employed again to address the influence of ripple loads on sustained-load cracking. Ripple loads can significantly reduce the apparent sustained load cracking resistance of titanium alloys in a relatively benign environment such as ambient air. For a ripple-load amplitude equal to 5% of the sustained load, the ripple-load cracking thresholds (K IRLC ) of beta-annealed Ti-6Al-4V and Ti-15V-3Cr-3al-3Sn are less than half of the respective sustained-load cracking thresholds (K ISLC ). The extent of ripple-load degradation for these alloys in ambient air -- relative to K ISLC , were found comparable to those observed in a much more aggressive 3.5% NaCl aqueous solution

  3. Performance analysis of active damped small DC-link capacitor based drive for unbalanced input voltage supply

    DEFF Research Database (Denmark)

    Maheshwari, Ram Krishan; Munk-Nielsen, Stig

    2011-01-01

    A small DC-link capacitor based drive is presented in this paper. The drive shows negative impedance instability at operating points with high power load. A phase portrait is presented for input filter states which exhibit a limit cycle. When the drive is operated with unbalanced input supply...

  4. Plantar flexor stretch reflex responses to whole body loading/unloading during human walking

    DEFF Research Database (Denmark)

    Grey, Michael James; van Doornik, Johannes; Sinkjær, Thomas

    2002-01-01

    Numerous animal and human studies have shown that afferent information from the periphery contributes to the control of walking. In particular, recent studies have consistently shown that load receptor input is an important element of the locomotion control mechanism. The objective of this study...... perturbation during human walking. Three body load conditions were investigated: normal body load, a 30% increase in body load, and a 30% decrease in body load. Healthy subjects walked on a treadmill at approximately 3.6 km/h with the left ankle attached to a portable stretching device. Dorsiflexion...... strongly to the corrective response of the stretch reflex in the plantar flexor muscles during walking....

  5. Value of Information by updating model uncertainties utilising proof loading in the context of series and Daniels systems

    DEFF Research Database (Denmark)

    Brüske, Henning; Thöns, Sebastian

    2016-01-01

    In this paper, an approach is presented for the determination of the Value of Information (VoI) in relation to models which can represent structural systems such as e.g. towers, cables, jackets. Stochastic capacities and loads are assumed for the models studied herein. The VoI is obtained......, the expected life-cycle benefit of the considered systems are computed. The difference in the expected benefits relating to the prior and pre-posterior decision analysis leads to the VoI. The system models are probabilistically computed using the Monte Carlo / Importance sampling simulations to estimate...... with a prior and a pre-posterior decision analysis. The prior decision analysis takes basis in the design phase of the structural system. Pre-posterior decision analysis builds upon modelling results of not yet conducted experiments. In order to perform the prior and pre-posterior Bayesian decision analysis...

  6. Earth-Space Links and Fade-Duration Statistics

    Science.gov (United States)

    Davarian, Faramaz

    1996-01-01

    In recent years, fade-duration statistics have been the subject of several experimental investigations. A good knowledge of the fade-duration distribution is important for the assessment of a satellite communication system's channel dynamics: What is a typical link outage duration? How often do link outages exceeding a given duration occur? Unfortunately there is yet no model that can universally answer the above questions. The available field measurements mainly come from temperate climatic zones and only from a few sites. Furthermore, the available statistics are also limited in the choice of frequency and path elevation angle. Yet, much can be learned from the available information. For example, we now know that the fade-duration distribution is approximately lognormal. Under certain conditions, we can even determine the median and other percentiles of the distribution. This paper reviews the available data obtained by several experimenters in different parts of the world. Areas of emphasis are mobile and fixed satellite links. Fades in mobile links are due to roadside-tree shadowing, whereas fades in fixed links are due to rain attenuation.

  7. Power System Stability Using Decentralized Under Frequency and Voltage Load Shedding

    DEFF Research Database (Denmark)

    Hoseinzadeh, Bakhtyar; Silva, Filipe Faria Da; Bak, Claus Leth

    2014-01-01

    information to shed the loads with higher voltage decay first. Therefore, this approach deals with coordination of voltage and frequency information instead of independent methods. Numerical simulations which are carried out in DigSilent PowerFactory software confirm the efficiency of proposed methodology...

  8. Spatial electric load forecasting

    CERN Document Server

    Willis, H Lee

    2002-01-01

    Containing 12 new chapters, this second edition contains offers increased-coverage of weather correction and normalization of forecasts, anticipation of redevelopment, determining the validity of announced developments, and minimizing risk from over- or under-planning. It provides specific examples and detailed explanations of key points to consider for both standard and unusual utility forecasting situations, information on new algorithms and concepts in forecasting, a review of forecasting pitfalls and mistakes, case studies depicting challenging forecast environments, and load models illustrating various types of demand.

  9. Low cognitive load strengthens distractor interference while high load attenuates when cognitive load and distractor possess similar visual characteristics.

    Science.gov (United States)

    Minamoto, Takehiro; Shipstead, Zach; Osaka, Naoyuki; Engle, Randall W

    2015-07-01

    Studies on visual cognitive load have reported inconsistent effects of distractor interference when distractors have visual characteristic that are similar to the cognitive load. Some studies have shown that the cognitive load enhances distractor interference, while others reported an attenuating effect. We attribute these inconsistencies to the amount of cognitive load that a person is required to maintain. Lower amounts of cognitive load increase distractor interference by orienting attention toward visually similar distractors. Higher amounts of cognitive load attenuate distractor interference by depleting attentional resources needed to process distractors. In the present study, cognitive load consisted of faces (Experiments 1-3) or scenes (Experiment 2). Participants performed a selective attention task in which they ignored face distractors while judging a color of a target dot presented nearby, under differing amounts of load. Across these experiments distractor interference was greater in the low-load condition and smaller in the high-load condition when the content of the cognitive load had similar visual characteristic to the distractors. We also found that when a series of judgments needed to be made, the effect was apparent for the first trial but not for the second. We further tested an involvement of working memory capacity (WMC) in the load effect (Experiment 3). Interestingly, both high and low WMC groups received an equivalent effect of the cognitive load in the first distractor, suggesting these effects are fairly automatic.

  10. Open Informational Ecosystems: The Missing Link for Sharing Educational Resources

    Science.gov (United States)

    Kerres, Michael; Heinen, Richard

    2015-01-01

    Open educational resources are not available "as such". Their provision relies on a technological infrastructure of related services that can be described as an informational ecosystem. A closed informational ecosystem keeps educational resources within its boundary. An open informational ecosystem relies on the concurrence of…

  11. Convection Weather Detection by General Aviation Pilots with Convectional and Data-Linked Graphical Weather Information Sources

    Science.gov (United States)

    Chamberlain, James P.; Latorella, Kara A.

    2001-01-01

    This study compares how well general aviation (GA) pilots detect convective weather in flight with different weather information sources. A flight test was conducted in which GA pilot test subjects were given different in-flight weather information cues and flown toward convective weather of moderate or greater intensity. The test subjects were not actually flying the aircraft, but were given pilot tasks representative of the workload and position awareness requirements of the en route portion of a cross country GA flight. On each flight, one test subject received weather cues typical of a flight in visual meteorological conditions (VMC), another received cues typical of flight in instrument meteorological conditions (IMC), and a third received cues typical of flight in IMC but augmented with a graphical weather information system (GWIS). The GWIS provided the subject with near real time data-linked weather products, including a weather radar mosaic superimposed on a moving map with a symbol depicting the aircraft's present position and direction of track. At several points during each flight, the test subjects completed short questionnaires which included items addressing their weather situation awareness and flight decisions. In particular, test subjects were asked to identify the location of the nearest convective cells. After the point of nearest approach to convective weather, the test subjects were asked to draw the location of convective weather on an aeronautical chart, along with the aircraft's present position. This paper reports preliminary results on how accurately test subjects provided with these different weather sources could identify the nearest cell of moderate or greater intensity along their route of flight. Additional flight tests are currently being conducted to complete the data set.

  12. Parallel interconnect for a novel system approach to short distance high information transfer data links

    Science.gov (United States)

    Raskin, Glenn; Lebby, Michael S.; Carney, F.; Kazakia, M.; Schwartz, Daniel B.; Gaw, Craig A.

    1997-04-01

    The OPTOBUSTM family of products provides for high performance parallel interconnection utilizing optical links in a 10-bit wide bi-directional configuration. The link is architected to be 'transparent' in that it is totally asynchronous and dc coupled so that it can be treated as a perfect cable with extremely low skew and no losses. An optical link consists of two identical transceiver modules and a pair of connectorized 62.5 micrometer multi mode fiber ribbon cables. The OPTOBUSTM I link provides bi- directional functionality at 4 Gbps (400 Mbps per channel), while the OPTOBUSTM II link will offer the same capability at 8 Gbps (800 Mbps per channel). The transparent structure of the OPTOBUSTM links allow for an arbitrary data stream regardless of its structure. Both the OPTOBUSTM I and OPTOBUSTM II transceiver modules are packaged as partially populated 14 by 14 pin grid arrays (PGA) with optical receptacles on one side of the module. The modules themselves are composed of several elements; including passives, integrated circuits optoelectronic devices and optical interface units (OIUs) (which consist of polymer waveguides and a specially designed lead frame). The initial offering of the modules electrical interface utilizes differential CML. The CML line driver sinks 5 mA of current into one of two pins. When terminated with 50 ohm pull-up resistors tied to a voltage between VCC and VCC-2, the result is a differential swing of plus or minus 250 mV, capable of driving standard PECL I/Os. Future offerings of the OPTOBUSTM links will incorporate LVDS and PECL interfaces as well as CML. The integrated circuits are silicon based. For OPTOBUSTM I links, a 1.5 micrometer drawn emitter NPN bipolar process is used for the receiver and an enhanced 0.8 micrometer CMOS process for the laser driver. For OPTOBUSTM II links, a 0.8 micrometer drawn emitter NPN bipolar process is used for the receiver and the driver IC utilizes 0.8 micrometer BiCMOS technology. The OPTOBUSTM

  13. Combined loading effects on the fracture mechanics behavior of line pipes

    Energy Technology Data Exchange (ETDEWEB)

    Bravo, R.E.; Cravero, S.; Ernst, H.A. [Tenaris Group, Campana (Argentina). SIDERCA R and D Center

    2009-12-19

    For certain applications, pipelines may be submitted to biaxial loading situations. In these cases, it is not clear the influence of the biaxial loading on the fracture mechanics behavior of cracked pipelines. For further understanding of biaxial loading effects, this work presents a numerical simulation of ductile tearing in a circumferentially surface cracked pipe under biaxial loading using the computational cell methodology. The model was adjusted with experimental results obtained in laboratory using single edge cracked under tension (SENT) specimens. These specimens appear as the better alternative to conventional fracture specimens to characterize fracture toughness of cracked pipes. The negligible effect of biaxial loadings on resistance curves was demonstrated. To guarantee the similarities of stress and strains fields between SENT specimens and cracked pipes subjected to biaxial loading, a constraint study using the J-Q methodology and the h parameter was used. The constraint study gives information about the characteristics of the crack-tip conditions. (author)

  14. Analysis and Synthesis of Load Forecasting Data for Renewable Integration Studies: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Steckler, N.; Florita, A.; Zhang, J.; Hodge, B. M.

    2013-11-01

    As renewable energy constitutes greater portions of the generation fleet, the importance of modeling uncertainty as part of integration studies also increases. In pursuit of optimal system operations, it is important to capture not only the definitive behavior of power plants, but also the risks associated with systemwide interactions. This research examines the dependence of load forecast errors on external predictor variables such as temperature, day type, and time of day. The analysis was utilized to create statistically relevant instances of sequential load forecasts with only a time series of historic, measured load available. The creation of such load forecasts relies on Bayesian techniques for informing and updating the model, thus providing a basis for networked and adaptive load forecast models in future operational applications.

  15. Robust resource loading for engineer-to-order manufacturing

    NARCIS (Netherlands)

    Wullink, Gerhard; Hans, Elias W.; van Harten, Aart

    2004-01-01

    Order acceptance decisions in Engineer-To-Order (ETO) environments are often based on incomplete or uncertain information about the order specifications and the status of the production system. To quote reliable due dates and manage the production system adequately, resource loading techniques that

  16. Cognitive load predicts point-of-care ultrasound simulator performance.

    Science.gov (United States)

    Aldekhyl, Sara; Cavalcanti, Rodrigo B; Naismith, Laura M

    2018-02-01

    The ability to maintain good performance with low cognitive load is an important marker of expertise. Incorporating cognitive load measurements in the context of simulation training may help to inform judgements of competence. This exploratory study investigated relationships between demographic markers of expertise, cognitive load measures, and simulator performance in the context of point-of-care ultrasonography. Twenty-nine medical trainees and clinicians at the University of Toronto with a range of clinical ultrasound experience were recruited. Participants answered a demographic questionnaire then used an ultrasound simulator to perform targeted scanning tasks based on clinical vignettes. Participants were scored on their ability to both acquire and interpret ultrasound images. Cognitive load measures included participant self-report, eye-based physiological indices, and behavioural measures. Data were analyzed using a multilevel linear modelling approach, wherein observations were clustered by participants. Experienced participants outperformed novice participants on ultrasound image acquisition. Ultrasound image interpretation was comparable between the two groups. Ultrasound image acquisition performance was predicted by level of training, prior ultrasound training, and cognitive load. There was significant convergence between cognitive load measurement techniques. A marginal model of ultrasound image acquisition performance including prior ultrasound training and cognitive load as fixed effects provided the best overall fit for the observed data. In this proof-of-principle study, the combination of demographic and cognitive load measures provided more sensitive metrics to predict ultrasound simulator performance. Performance assessments which include cognitive load can help differentiate between levels of expertise in simulation environments, and may serve as better predictors of skill transfer to clinical practice.

  17. The Influence of Load and Speed on Individuals' Movement Behavior.

    Science.gov (United States)

    Frost, David M; Beach, Tyson A C; Callaghan, Jack P; McGill, Stuart M

    2015-09-01

    Because individuals' movement patterns have been linked to their risk of future injury, movement evaluations have become a topic of interest. However, if individuals adapt their movement behavior in response to the demands of a task, the utility of evaluations comprising only low-demand activities could have limited application with regard to the prediction of future injury. This investigation examined the impact of load and speed on individuals' movement behavior. Fifty-two firefighters performed 5 low-demand (i.e., light load, low movement speed) whole-body tasks (i.e., lift, squat, lunge, push, and pull). Each task was then modified by increasing the speed, external load, or speed and load. Select measures of motion were used to characterize the performance of each task, and comparisons were made between conditions. The participants adapted their movement behavior in response to the external demands of a task (64 and 70% of all the variables were influenced [p ≤ 0.05] by changing the load and speed, respectively), but in a manner unique to the task and type of demand. The participants exhibited greater spine and frontal plane knee motion in response to an increase in speed when compared with increasing loads. However, there were a large number of movement strategies exhibited by individual firefighters that differed from the group's response. The data obtained here imply that individuals may not be physically prepared to perform safely or effectively when a task's demands are elevated simply because they exhibit the ability to perform a low-demand activity with competence. Therefore, movement screens comprising only low-demand activities may not adequately reflect an individual's capacity, or their risk of injury, and could adversely affect any recommendations that are made for training or job performance.

  18. In Respect to the Cognitive Load Theory: Adjusting Instructional Guidance with Student Expertise.

    Science.gov (United States)

    Schilling, Jim

    2017-01-01

    The amount of guidance supplied by educators to students in allied health programs is a factor in student learning. According to the cognitive load theory of learning, without adequate instructional support, novice learners will be overwhelmed and unable to store information, while unnecessary guidance supplied to advanced students will cause extraneous cognitive load on the working memory system. Adjusting instructional guidance for students according to their level of expertise to minimize extraneous cognitive load and optimize working memory storage capacity will enhance learning effectiveness. Novice students presented with complex subject matter require significant guidance during the initial stages, using strategies such as worked examples. As students comprehend information, instructional guidance needs to gradually fade to avoid elevated extraneous cognitive load from the expertise reversal effect. An instructional strategy that utilizes a systemic (fixed) or adjustable (adaptive) tapering of guidance to students in allied health programs depending on their expertise will optimize learning capability.

  19. Load Lugging Locomotion: Lessons from Indigenous People, Rhino Beetles, and Wallabies

    Science.gov (United States)

    2001-05-01

    they consume metabolic energy at the same rate! Even hopping at a 4-minute mile pace, kangaroos are only at about a third of their aerobic capacity...carried for free. However, there is not a clear link between the mechanical work performed in walking and the metabolic cost. Rhinoceros beetles are...more cheaply. But kangaroos and wallabies can use internal springs to save energy during their hopping gait and to carry loads in their pouches. These

  20. Total maximum allocated load calculation of nitrogen pollutants by linking a 3D biogeochemical-hydrodynamic model with a programming model in Bohai Sea

    Science.gov (United States)

    Dai, Aiquan; Li, Keqiang; Ding, Dongsheng; Li, Yan; Liang, Shengkang; Li, Yanbin; Su, Ying; Wang, Xiulin

    2015-12-01

    The equal percent removal (EPR) method, in which pollutant reduction ratio was set as the same in all administrative regions, failed to satisfy the requirement for water quality improvement in the Bohai Sea. Such requirement was imposed by the developed Coastal Pollution Total Load Control Management. The total maximum allocated load (TMAL) of nitrogen pollutants in the sea-sink source regions (SSRs) around the Bohai Rim, which is the maximum pollutant load of every outlet under the limitation of water quality criteria, was estimated by optimization-simulation method (OSM) combined with loop approximation calculation. In OSM, water quality is simulated using a water quality model and pollutant load is calculated with a programming model. The effect of changes in pollutant loads on TMAL was discussed. Results showed that the TMAL of nitrogen pollutants in 34 SSRs was 1.49×105 ton/year. The highest TMAL was observed in summer, whereas the lowest in winter. TMAL was also higher in the Bohai Strait and central Bohai Sea and lower in the inner area of the Liaodong Bay, Bohai Bay and Laizhou Bay. In loop approximation calculation, the TMAL obtained was considered satisfactory for water quality criteria as fluctuation of concentration response matrix with pollutant loads was eliminated. Results of numerical experiment further showed that water quality improved faster and were more evident under TMAL input than that when using the EPR method

  1. Population distribution of flexible molecules from maximum entropy analysis using different priors as background information: application to the Φ, Ψ-conformational space of the α-(1-->2)-linked mannose disaccharide present in N- and O-linked glycoproteins.

    Science.gov (United States)

    Säwén, Elin; Massad, Tariq; Landersjö, Clas; Damberg, Peter; Widmalm, Göran

    2010-08-21

    The conformational space available to the flexible molecule α-D-Manp-(1-->2)-α-D-Manp-OMe, a model for the α-(1-->2)-linked mannose disaccharide in N- or O-linked glycoproteins, is determined using experimental data and molecular simulation combined with a maximum entropy approach that leads to a converged population distribution utilizing different input information. A database survey of the Protein Data Bank where structures having the constituent disaccharide were retrieved resulted in an ensemble with >200 structures. Subsequent filtering removed erroneous structures and gave the database (DB) ensemble having three classes of mannose-containing compounds, viz., N- and O-linked structures, and ligands to proteins. A molecular dynamics (MD) simulation of the disaccharide revealed a two-state equilibrium with a major and a minor conformational state, i.e., the MD ensemble. These two different conformation ensembles of the disaccharide were compared to measured experimental spectroscopic data for the molecule in water solution. However, neither of the two populations were compatible with experimental data from optical rotation, NMR (1)H,(1)H cross-relaxation rates as well as homo- and heteronuclear (3)J couplings. The conformational distributions were subsequently used as background information to generate priors that were used in a maximum entropy analysis. The resulting posteriors, i.e., the population distributions after the application of the maximum entropy analysis, still showed notable deviations that were not anticipated based on the prior information. Therefore, reparameterization of homo- and heteronuclear Karplus relationships for the glycosidic torsion angles Φ and Ψ were carried out in which the importance of electronegative substituents on the coupling pathway was deemed essential resulting in four derived equations, two (3)J(COCC) and two (3)J(COCH) being different for the Φ and Ψ torsions, respectively. These Karplus relationships are denoted

  2. Distribution load estimation (DLE)

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A; Lehtonen, M [VTT Energy, Espoo (Finland)

    1998-08-01

    The load research has produced customer class load models to convert the customers` annual energy consumption to hourly load values. The reliability of load models applied from a nation-wide sample is limited in any specific network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to find improvements to the load models or, in general, improvements to the load estimates. In Distribution Load Estimation (DLE) the measurements from the network are utilized to improve the customer class load models. The results of DLE will be new load models that better correspond to the loading of the distribution network but are still close to the original load models obtained by load research. The principal data flow of DLE is presented

  3. EPR: High load variation performances with the 'Tmode' core control

    International Nuclear Information System (INIS)

    Grossetete, A.

    2008-01-01

    The load variation performances on a PWR are directly linked to the core control design. This design is mainly characterized by the definition of the control rod banks and the way to both perform the banks movements and to modify the core boron concentration by injection of boric acid or water. The following paper presents the principles of the T mode, the new fully automatic core control mode for the EPR which provides high performance in terms of maneuverability and optimizes the effluents. First, the paper describes the division of the control rods into two control banks (Pbank for temperature and Hbank for power distribution). Then typical movements of these banks during power changes are shown. Then, the principle of the 3 control loops (Tave, AO, Pmax), used to obtain these desired control rod movements, is given. Finally, a load following transient simulation is presented. (authors)

  4. EPR: high load variation performances with the 'TMODE' core control

    International Nuclear Information System (INIS)

    Pairot, Frederic

    2008-01-01

    The load variation performances on a PWR are directly linked to the core control design. This design is mainly characterized by the definition of the control rod banks and the way to both perform the banks movements and to modify the core boron concentration by injection of boric acid or water. The following paper presents the principles of the T mode, the new fully automatic core control mode for the EPR which provides high performance in terms of maneuverability and optimizes the effluents. First, the paper describes the division of the control rods into two control banks (Pbank for temperature and Hbank for power distribution). Then typical movements of these banks during power changes are shown. Then, the principle of the 3 control loops (Tave, AO, Pmax), used to obtain these desired control rod movements, is given. Finally, a load following transient simulation is presented. (author)

  5. Genetics Home Reference: X-linked dilated cardiomyopathy

    Science.gov (United States)

    ... The other conditions in the spectrum, Duchenne and Becker muscular dystrophy , are characterized by progressive weakness and wasting of ... linked dilated cardiomyopathy is sometimes classified as subclinical Becker muscular dystrophy. Related Information What does it mean if a ...

  6. Residential Load Manageability Factor Analyses by Load Sensitivity Affected by Temperature

    Directory of Open Access Journals (Sweden)

    N. Eskandari

    2016-12-01

    Full Text Available Load side management is the basic and significant principle to keeping the balance between generation side and consumption side of electrical power energy. Load side management on typical medium voltage feeder is the power energy consumption control of connected loads with variation of essential parameters that loads do reaction to their variation. Knowing amount of load's reaction to each parameters variation in typical medium voltage feeder during the day, leads to gain Load Manageability Factor (LMF for that specific feeder that helps power utilities to manage their connected loads. Calculating this LMF needs to find out each types of load with unique inherent features behavior to each parameters variation. This paper results and future work results will help us to catch mentioned LMF. In this paper analysis of residential load behavior due to temperature variation with training artificial neural network will be done. Load behavior due to other essential parameters variations like energy pricing variation, major event happening, and power utility announcing to the customers, and etc will study in future works. Collecting all related works results in a unit mathematical equation or an artificial neural network will gain LMF.

  7. PROPOSALS FOR MEASURING THE INFORMATION LOAD OF MEDIA MESSAGES AND ITS EFFECTS

    Directory of Open Access Journals (Sweden)

    Luís Fernando Morales Morante

    2013-04-01

    Full Text Available This article offers a reflection about the validity of basic concepts that define the grammar and structure of audiovisual discourses and its functionality in current communication processes dominated by digital convergence and interactivity. Also, the article offers a theoretical proposal for measuring the load of messages and its expressive-narrative communicative behavior, that is based on semantic coherence (the element that matches the communicative intention of the sender and receiver's attention.

  8. Load Management in Residential Buildings Considering Techno-Economic and Environmental Aspects

    Energy Technology Data Exchange (ETDEWEB)

    Abaravicius, Juozas

    2004-12-01

    Load problems in electricity markets occur both on the supply and demand side and can have technical, economic and even political causes. Commonly, such problems have been solved by expanding production and/or distribution capacity, importing electricity or by load management. Load management is a techno-economic measure for harmonizing the relations between supply and demand sides, optimizing power generation and transmission and increasing security of supply. Interest in load management differs depending on the perspective of the actors involved: from customer, utility, or producer to state policy maker. The problem of load demand and load management in residential sector is in this thesis approached from different perspectives, i.e. technical, economic, and environmental. The study does not go deep into detailed analyses of each perspective, but rather aims to establish and analyze the links between them. This trans-disciplinary approach is the key methodological moment used in the research work performed by the research group for load management in buildings at the Lund Institute of Technology. The key objective of this study is to analyze load demand variation and load management possibilities in residential sector, particularly detached and semi-detached houses, to experimentally test and analyze the conditions and potential of direct load management from customer and utility viewpoint. Techno-economic and environmental aspects are investigated. The study was performed in collaboration with one electric utility in Southern Sweden. Ten electric-heated houses were equipped with extra meters, enabling hourly load measurements for heating, hot water and total electricity use. Household heating and hot water systems were controlled by the utility using an existing remote reading and monitoring system. The residents noticed some of the control periods, although they didn't express any larger discomfort. The experiments proved that direct load management might

  9. A new perspective on the perceptual selectivity of attention under load

    DEFF Research Database (Denmark)

    Giesbrecht, Barry; Sy, Jocelyn; Bundesen, Claus

    2014-01-01

    The human attention system helps us cope with a complex environment by supporting the selective processing of information relevant to our current goals. Understanding the perceptual, cognitive, and neural mechanisms that mediate selective attention is a core issue in cognitive neuroscience. One...... prominent model of selective attention, known as load theory, offers an account of how task demands determine when information is selected and an account of the efficiency of the selection process. However, load theory has several critical weaknesses that suggest that it is time for a new perspective. Here...... is integrated to provide efficient attentional selection and allocation of perceptual processing resources....

  10. Social Information Links Individual Behavior to Population and Community Dynamics.

    Science.gov (United States)

    Gil, Michael A; Hein, Andrew M; Spiegel, Orr; Baskett, Marissa L; Sih, Andrew

    2018-05-07

    When individual animals make decisions, they routinely use information produced intentionally or unintentionally by other individuals. Despite its prevalence and established fitness consequences, the effects of such social information on ecological dynamics remain poorly understood. Here, we synthesize results from ecology, evolutionary biology, and animal behavior to show how the use of social information can profoundly influence the dynamics of populations and communities. We combine recent theoretical and empirical results and introduce simple population models to illustrate how social information use can drive positive density-dependent growth of populations and communities (Allee effects). Furthermore, social information can shift the nature and strength of species interactions, change the outcome of competition, and potentially increase extinction risk in harvested populations and communities. Copyright © 2018 Elsevier Ltd. All rights reserved.

  11. Aluminium and Alzheimer's disease: the science that describes the link

    National Research Council Canada - National Science Library

    Exley, Christopher

    2001-01-01

    ... that has been encircled is the gene for the amyloid precursor protein. (Thanks to Walter Lukiw for supplying this information.) Aluminium and Alzheimer's Disease: The Science that Describes the LinkAluminium and Alzheimer's Disease The Science that Describes the Link Edited by Christopher Exley Birchall Centre for Inorganic Chemistry and Materials Scienc...

  12. Opposite Effects of Capacity Load and Resolution Load on Distractor Processing

    OpenAIRE

    Zhang, Weiwei; Luck, Steven J.

    2014-01-01

    According to the load theory of attention, an increased perceptual load reduces distractor processing whereas an increased working memory load facilitates distractor processing. Here we raise the possibility that the critical distinction may instead be between an emphasis on resolution and an emphasis on capacity. That is, perceptual load manipulations typically emphasize resolution (fine-grained discriminations), whereas working memory load manipulations typically emphasize capacity (simulta...

  13. Direct FEM-computation of load carrying capacity of highly loaded passive components; Direkte FEM - Berechnung der Tragfaehigkeit hochbeanspruchter passiver Komponenten

    Energy Technology Data Exchange (ETDEWEB)

    Staat, M; Heitzer, M [Forschungszentrum Juelich GmbH (Germany). Inst. fuer Sicherheitsforschung und Reaktortechnik

    1998-11-01

    Detailed, inelastic FEM analyses yield accurate information about the stresses and deformations in passive components. The local loading conditions, however, cannot be directly compared with a limit load in terms of structural mechanics. Concentration on the load carrying capacity is an approach simplifying the analysis. Based on the plasticity theory, limit and shakedown analyses calculate the load carrying capacities directly and exactly. The paper explains the implementation of the limit and shakedown data sets in a general FEM program and the direct calculation of the load carrying capacities of passive components. The concepts used are explained with respect to common structural analysis. Examples assuming high local stresses illustrate the application of FEM-based limit and shakedown analyses. The calculated interaction diagrams present a good insight into the applicable operational loads of individual passive components. The load carrying analysis also opens up a structure mechanics-based approach to assessing the load-to-collapse of cracked components made of highly ductile fracture-resistant material. (orig./CB) [Deutsch] Genaue Kenntnis der Spannungen und Verformungen in passiven Komponenten gewinnt man mit detailierten inelastischen FEM Analysen. Die lokale Beanspruchung laesst sich aber nicht direkt mit einer Beanspruchbarkeit im strukturmechanischen Sinne vergleichen. Konzentriert man sich auf die Frage nach der Tragfaehigkeit, dann vereinfacht sich die Analyse. Im Rahmen der Plastizitaetstheorie berechnen Traglast- und Einspielanalyse die tragbaren Lasten direkt und exakt. In diesem Beitrag wird eine Implementierung der Traglast- und Einspielsaetze in ein allgemeines FEM Programm vorgestellt, mit der die Tragfaehigkeit passiver Komponenten direkt berechnet wird. Die benutzten Konzepte werden in Bezug auf die uebliche Strukturanalyse erlaeutert. Beispiele mit lokal hoher Beanspruchung verdeutlichen die Anwendung der FEM basierten Traglast- und

  14. Pay for load demand - electricity pricing with load demand component

    International Nuclear Information System (INIS)

    Pyrko, Jurek; Sernhed, Kerstin; Abaravicius, Juozas

    2003-01-01

    This publication is part of a project called Direct and Indirect Load Control in Buildings. Peak load problems have attracted considerable attention in Sweden during last three winters, caused by a significant decrease in available reserve power, which is a consequence of political decisions and liberalisation of the electricity market. A possible way to lower peak loads, avoiding electricity shortages and reducing electricity costs both for users and utilities, is to make customers experience the price difference during peak load periods and, in this way, become more aware of their energy consumption pattern and load demand. As of January 1st 2001, one of the Swedish energy utilities - Sollentuna Energi - operating in the Stockholm area, introduced a new electricity tariff with differentiated grid fees based on a mean value of the peak load every month. This tariff was introduced for all residential customers in the service area. The objective of this study is to investigate the extent to which a Load Demand Component, included in electricity pricing, can influence energy use and load demand in residential buildings. What are the benefits and disadvantages for customers and utilities? This paper investigates the impact of the new tariff on the utility and different types of typical residential customers, making comparisons with previous tariff. Keywords Load demand, electricity pricing, tariff, residential customers, energy behaviour

  15. Digital Drug Dosing: Dosing in Drug Assays by Light-Defined Volumes of Hydrogels with Embedded Drug-Loaded Nanoparticles

    DEFF Research Database (Denmark)

    Faralli, Adele; Melander, Fredrik; Larsen, Esben Kjær Unmack

    2014-01-01

    Polyethylene glycol (PEG)-based hydrogels are widely used for biomedical applications, including matrices for controlled drug release. We present a method for defining drug dosing in screening assays by light-activated cross-linking of PEG-diacrylate hydrogels with embedded drug-loaded liposome...

  16. Comparative limb bone loading in the humerus and femur of the tiger salamander: testing the 'mixed-chain' hypothesis for skeletal safety factors.

    Science.gov (United States)

    Kawano, Sandy M; Economy, D Ross; Kennedy, Marian S; Dean, Delphine; Blob, Richard W

    2016-02-01

    Locomotion imposes some of the highest loads upon the skeleton, and diverse bone designs have evolved to withstand these demands. Excessive loads can fatally injure organisms; however, bones have a margin of extra protection, called a 'safety factor' (SF), to accommodate loads that are higher than normal. The extent to which SFs might vary amongst an animal's limb bones is unclear. If the limbs are likened to a chain composed of bones as 'links', then similar SFs might be expected for all limb bones because failure of the system would be determined by the weakest link, and extra protection in other links could waste energetic resources. However, Alexander proposed that a 'mixed-chain' of SFs might be found amongst bones if: (1) their energetic costs differ, (2) some elements face variable demands, or (3) SFs are generally high. To test whether such conditions contribute to diversity in limb bone SFs, we compared the biomechanical properties and locomotor loading of the humerus and femur in the tiger salamander (Ambystoma tigrinum). Despite high SFs in salamanders and similar sizes of the humerus and femur that would suggest similar energetic costs, the humerus had lower bone stresses, higher mechanical hardness and larger SFs. SFs were greatest in the anatomical regions where yield stresses were highest in the humerus and lowest in the femur. Such intraspecific variation between and within bones may relate to their different biomechanical functions, providing insight into the emergence of novel locomotor capabilities during the invasion of land by tetrapods. © 2016. Published by The Company of Biologists Ltd.

  17. Direct transverse load profile determination using the polarization-dependent loss spectral response of a chirped fiber Bragg grating.

    Science.gov (United States)

    Descamps, Frédéric; Bette, Sébastien; Kinet, Damien; Caucheteur, Christophe

    2016-06-01

    The determination of stress profiles created by transverse loads was proved to be important in different domains, such as structural health monitoring and biomechanics, and, more specifically, in the prostheses domain. In this paper, we report an original method to estimate the transverse load profile from the polarization-dependent loss (PDL) spectrum of a chirped fiber Bragg grating (CFBG). This method makes use of the relationship between the integration of the PDL of a CFBG, and the force profile has the advantage of not requiring any iterative method to estimate the transverse load profile. The relationship linking the integration of the PDL and the force profile is demonstrated using an analytical approximation of the transmission spectrum of CFBGs. The validity of this method for the determination of non-uniform load profiles is then shown using a numerical analysis. An experimental demonstration is finally reported using a 48 mm-long CFBG subject to different step transverse load profiles.

  18. Dynamic axle and wheel loads identification: laboratory studies

    Science.gov (United States)

    Zhu, X. Q.; Law, S. S.

    2003-12-01

    Two methods have been reported by Zhu and Law to identify moving loads on the top of a bridge deck. One is based on the exact solution (ESM) and the other is based on the finite element formulation (FEM). Simulation studies on the effect of different influencing factors have been reported previously. This paper comparatively studies the performances of these two methods with experimental measurements obtained from a bridge/vehicle system in the laboratory. The strains of the bridge deck are measured when a model car moves across the bridge deck along different paths. The moving loads on the bridge deck are identified from the measured strains using these two methods, and the responses are reconstructed from the identified loads for comparison with the measured responses to verify the performances of these methods. Studies on the identification accuracy due to the effect of the number of vibration mode used, the number of measuring points and eccentricities of travelling paths are performed. Results show that the ESM could identify the moving loads individually or as axle loads when they are travelling at an eccentricity with the sensors located close to the travelling path of the forces. And the accuracy of the FEM is dependent on the amount of measured information used in the identification.

  19. Hybrid ellipsoidal fuzzy systems in forecasting regional electricity loads

    Energy Technology Data Exchange (ETDEWEB)

    Pai, Ping-Feng [Department of Information Management, National Chi Nan University, 1 University Road, Puli, Nantou 545, Taiwan (China)

    2006-09-15

    Because of the privatization of electricity in many countries, load forecasting has become one of the most crucial issues in the planning and operations of electric utilities. In addition, accurate regional load forecasting can provide the transmission and distribution operators with more information. The hybrid ellipsoidal fuzzy system was originally designed to solve control and pattern recognition problems. The main objective of this investigation is to develop a hybrid ellipsoidal fuzzy system for time series forecasting (HEFST) and apply the proposed model to forecast regional electricity loads in Taiwan. Additionally, a scaled conjugate gradient learning method is employed in the supervised learning phase of the HEFST model. Subsequently, numerical data taken from the existing literature is used to demonstrate the forecasting performance of the HEFST model. Simulation results reveal that the proposed model has better forecasting performance than the artificial neural network model and the regression model. Thus, the HEFST model is a valid and promising alternative for forecasting regional electricity loads. (author)

  20. Linking attentional processes and conceptual problem solving: visual cues facilitate the automaticity of extracting relevant information from diagrams.

    Science.gov (United States)

    Rouinfar, Amy; Agra, Elise; Larson, Adam M; Rebello, N Sanjay; Loschky, Lester C

    2014-01-01

    This study investigated links between visual attention processes and conceptual problem solving. This was done by overlaying visual cues on conceptual physics problem diagrams to direct participants' attention to relevant areas to facilitate problem solving. Participants (N = 80) individually worked through four problem sets, each containing a diagram, while their eye movements were recorded. Each diagram contained regions that were relevant to solving the problem correctly and separate regions related to common incorrect responses. Problem sets contained an initial problem, six isomorphic training problems, and a transfer problem. The cued condition saw visual cues overlaid on the training problems. Participants' verbal responses were used to determine their accuracy. This study produced two major findings. First, short duration visual cues which draw attention to solution-relevant information and aid in the organizing and integrating of it, facilitate both immediate problem solving and generalization of that ability to new problems. Thus, visual cues can facilitate re-representing a problem and overcoming impasse, enabling a correct solution. Importantly, these cueing effects on problem solving did not involve the solvers' attention necessarily embodying the solution to the problem, but were instead caused by solvers attending to and integrating relevant information in the problems into a solution path. Second, this study demonstrates that when such cues are used across multiple problems, solvers can automatize the extraction of problem-relevant information extraction. These results suggest that low-level attentional selection processes provide a necessary gateway for relevant information to be used in problem solving, but are generally not sufficient for correct problem solving. Instead, factors that lead a solver to an impasse and to organize and integrate problem information also greatly facilitate arriving at correct solutions.