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Sample records for line rx aur

  1. Time dependence of the UV resonance lines in the cataclysmic variables SU UMa, RX And and 0623+71

    Woods, J.A.; Drew, J.E.; Verbunt, Frank

    1990-01-01

    We present IUE observations of the dwarf novae SU UMa and RX And, and of the nova-like variable 0623 + 71. At the time of observation, SU UMa and RX And were in outburst. All three systems show variability in the wind-formed UV resonance lines of N v λ 1240, Si IV λ 1397 and C IV λ 1549 on timescale of hours. The amplitude of variation is smallest in RX And and largest in 0623 + 71. There is evidence that the variations observed in SU UMa's UV spectrum repeat on the orbital period. Our observations of SU UMa also reveal variability in the continuum flux during the decline from outburst maximum that is much more marked in the UV than at optical wavelengths. (author)

  2. Popular Herbig AE star AB Aur

    Shevchenko, V.S.

    1987-01-01

    The variability of AB Aur emission line H α , H β , H γ profiles, equivalent widths (EW λ ) and relative intensity have been observed on the photoelectric scanner. During the 20 d observation period EW λ H α ranged from 23.20 to 35.35 A. Mean EW λ H α is 27.25 A, daily average deviation is 3.60 ± 0.07 A. The minimum time of variability is 1 h . The chromospheric lines near-infrared triplet Ca II and KCaII and emission lines H β -H13, P12-P20, 0I 8446.5 A and the variability of other lines have been studied on the photographic and image-tube spectra. The intensity of these lines and EW λ changed 2-4 times during an interval from 1 h to several years. The AB Aur variability nature of emission lines made it possible to assume that the ''deep chromosphere'' is not a centre-symmetrical or axisymmetrical formation but is a conglomerate of different density and speed gas condensations

  3. RxClass

    U.S. Department of Health & Human Services — The RxClass Browser is a web application for exploring and navigating through the class hierarchies to find the RxNorm drug members associated with each class....

  4. RxTerms

    U.S. Department of Health & Human Services — RxTerms is a drug interface terminology derived from RxNorm for prescription writing or medication history recording (e.g. in e-prescribing systems, PHRs). RxTerms...

  5. NuSTAR discovery of a cyclotron line in the Be/X-ray binary RX J0520.5–6932 during outburst

    Tendulkar, Shriharsh P.; Fürst, Felix; Harrison, Fiona A.; Walton, Dominic J. [Space Radiation Laboratory, California Institute of Technology, 1200 East California Boulevard, MC 249-17, Pasadena, CA 91125 (United States); Pottschmidt, Katja [Center for Research and Exploration in Space Science and Technology, University of Maryland, Baltimore County, Baltimore, MD 21250 (United States); Bachetti, Matteo [Université de Toulouse, UPS-OMP, IRAP, F-31400 Toulouse (France); Bhalerao, Varun B. [Inter-University Centre for Astronomy and Astrophysics, Post Bag 4, Ganeshkhind, Pune University Campus, Pune 411007 (India); Boggs, Steven E.; Tomsick, John A. [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); Christensen, Finn E. [DTU Space, National Space Institute, Technical University of Denmark, Elektrovej 327, DK-2800 Lyngby (Denmark); Craig, William W.; Hailey, Charles A. [Columbia Astrophysics Laboratory, Columbia University, New York, NY 10027 (United States); Stern, Daniel [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Zhang, William, E-mail: spt@astro.caltech.edu [NASA Goddard Space Flight Center, Astrophysics Science Division, Code 661, Greenbelt, MD 20771 (United States)

    2014-11-10

    We present spectral and timing analysis of NuSTAR observations of RX J0520.5–6932 in the 3-79 keV band collected during its outburst in 2014 January. The target was observed on two epochs and we report the detection of a cyclotron resonant scattering feature with central energies of E{sub CRSF}=31.3{sub −0.7}{sup +0.8} keV and 31.5{sub −0.6}{sup +0.7} keV during the two observations, respectively, corresponding to a magnetic field of B ≈ 2 × 10{sup 12} G. The 3-79 keV luminosity of the system during the two epochs, assuming a nominal distance of 50 kpc, was 3.667 ± 0.007 × 10{sup 38} erg s{sup –1} and 3.983 ± 0.007 × 10{sup 38} erg s{sup –1}. Both values are much higher than the critical luminosity of ≈1.5 × 10{sup 37} erg s{sup –1}, above which a radiation-dominated shock front may be expected. This adds a new object to the sparse set of three systems that have a cyclotron line observed at luminosities in excess of 10{sup 38} erg s{sup –1}. A broad (σ ≈ 0.45 keV) Fe emission line is observed in the spectrum at a central energy of 6.58{sub −0.05}{sup +0.05} keV in both epochs. The pulse profile of the pulsar was observed to be highly asymmetric with a sharply rising and slowly falling profile of the primary peak. We also observed minor variations in the cyclotron line energy and width as a function of the rotation phase.

  6. RX: a nonimaging concentrator.

    Miñano, J C; Benítez, P; González, J C

    1995-05-01

    A detailed description of the design procedure for a new concentrator, RX, and some examples of it's use are given. The method of design is basically the same as that used in the design of two other concentrators: the RR and the XR [Appl. Opt. 31, 3051 (1992)]. The RX is ideal in two-dimensional geometry. The performance of the rotational RX is good when the average angular spread of the input bundle is small: up to 95% of the power of the input bundle can be transferred to the output bundle (with the assumption of a constant radiance for the rays of the input bundle).

  7. RxNorm

    U.S. Department of Health & Human Services — RxNorm provides normalized names for clinical drugs and links its names to many of the drug vocabularies commonly used in pharmacy management and drug interaction...

  8. Steam in RX Puppis

    Barton, J R; Phillips, B A; Allen, D A [Anglo-Australian Observatory, Epping (Australia)

    1979-06-01

    The presence of H/sub 2/O and CO absorption in RX Puppis is demonstrated by means of 2-..mu..m spectroscopy. The existence of a Mira variable in this star is thereby confirmed. These data are not easily reconciled with a recent model in which a single B giant is invoked as the central energy source. It is believed instead that RX Pup is explicable in terms of a symbiotic binary model.

  9. Rx for Library Management.

    Cage, Alvin C.

    1986-01-01

    Examines recent developments in field of systems theory that can improve library management practices by broadening perspective in which these problems may be approached. The concept of organizational life cycles is discussed and a paradigm for application of its principles is developed. An Rx decision chart is appended. (9 references) (EJS)

  10. Spectral monitoring of AB Aur

    Rodríguez Díaz, L. F.; Oostra, B.

    2017-07-01

    The Astronomical Observatory of the Universidad de los Andes in Bogotá, Colombia, did a spectral monitoring during 2014 and 2015 to AB Aurigae, the brightest Herbig Ae/be star in the northern hemisphere. The aim of this project is applying spectral techniques, in order to identify specific features that could help us not only to understand how this star is forming, but also to establish a pattern to explain general star formation processes. We have recorded 19 legible spectra with a resolving power of R = 11,0000, using a 40 cm Meade telescope with an eShel spectrograph, coupled by a 50-micron optical fiber. We looked for the prominent absorption lines, the Sodium doublet at 5890Å and 5896Å, respectively and Magnesium II at 4481Å; to measure radial velocities of the star, but, we did not find a constant value. Instead, it ranges from 15 km/s to 32 km/s. This variability could be explained by means of an oscillation or pulsation of the external layers of the star. Other variabilities are observed in some emission lines: Hα, Hβ, He I at 5876Å and Fe II at 5018Å. It seems this phenomenon could be typical in stars that are forming and have a circumstellar disk around themselves. This variability is associated with the nonhomogeneous surface of the star and the interaction that it has with its disk. Results of this interaction could be seen also in the stellar wind ejected by the star. More data are required in order to look for a possible period in the changes of radial velocity of the star, the same for the variability of He I and Fe II, and phenomena present in Hα. We plan to take new data in January of 2017.

  11. Epsilon Aur monitoring during predicted pulsation phase

    Waagen, Elizabeth O.; Templeton, Matthew R.

    2014-09-01

    Dr. Robert Stencel (University of Denver Astronomy Program) has requested that AAVSO observers monitor epsilon Aurigae from now through the end of the observing season. "Studies of the long-term, out-of-eclipse photometry of this enigmatic binary suggest that intervals of coherent pulsation occur at roughly 1/3 of the 27.1-year orbital period. Kloppenborg, et al. noted that stable variation patterns develop at 3,200-day intervals' implying that 'the next span of dates when such events might happen are circa JD ~2457000 (2014 December)'. "These out-of-eclipse light variations often have amplitudes of ~0.1 magnitude in U, and ~0.05 in V, with characteristic timescales of 60-100 days. The AAVSO light curve data to the present may indicate that this coherent phenomenon has begun, but we encourage renewed efforts by observers...to help deduce whether these events are internal to the F star, or externally-driven by tidal interaction with the companion star." Nightly observations or one observation every few days (CCD/PEP/DSLR, VUBR (amplitude too small for visual)) are requested. Finder charts with sequence may be created using the AAVSO Variable Star Plotter (http://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. Epsilon Aur was the subject of major international campaigns and the AAVSO's Citizen Sky project as it went through its 27.1-year eclipse in 2009-2011. Over 700 observers worldwide submitted over 20,000 multicolor observations to the AAVSO International Database for this project. Much information on eps Aur is available from the AAVSO, including material on the Citizen Sky website (http://www.aavso.org/epsilon-aurigae and http://www.citizensky.org/content/star-our-project). The Journal of the AAVSO, Volume 40, No. 2 (2012) was devoted to discussion of and research results from this event. See full Alert Notice for more details and observations.

  12. NuSTAR Discovery of a Cyclotron Line in the Be/X-ray Binary RX J0520.5-6932 During Outburst

    Tendulkar, Shriharsh P.; Fürst, Felix; Pottschmidt, Katja

    2014-01-01

    that have a cyclotron line observed at luminosities in excess of $10^{38}\\,\\mathrm{erg\\,s^{-1}}$. A broad ($\\sigma\\approx0.45$ keV) Fe emission line is observed in the spectrum at a central energy of $6.58_{-0.05}^{+0.05}$ keV in both epochs. The pulse profile of the pulsar was observed to be highly...

  13. RW Aur A FROM THE X-WIND POINT OF VIEW: GENERAL FEATURES

    Liu, Chun-Fan; Shang, Hsien

    2012-01-01

    In this paper, the RW Aur A microjet is studied from the point of view of X-wind models. The archived Hubble Space Telescope/STIS spectra of the optical forbidden lines [O I], [S II], and [N II] from RW Aur A, taken in Cycle 8 with seven parallel slits along the jet axis, spaced at 0.''07 apart, were analyzed. Images, position-velocity diagrams, and line ratios among the species were constructed, and compared with synthetic observations generated by selected solutions of the X-wind. Prominent features arising in a steady-state X-wind could be identified within the convolved images and position-velocity diagrams, including FWHM and high-velocity peaks on both of the redshifted and blueshifted jets. The well-known asymmetric velocity profiles of the opposite jets were built into the selected models. We discuss model selections within the existing uncertainties of the stellar parameters and inclination angle of the system. In this framework, the mass-loss rates that were inferred to be decreasing along the jet axis in the literature are the results of slowly decreasing excitation conditions and electron density profiles. Despite the apparent asymmetry in the terminal velocities, line intensities and mass-loss rates, the average linear momenta from the opposite sides of the jet are actually balanced. These previously hard-to-explain features of the asymmetric RW Aur A jet system can now be interpreted in a different but self-consistent manner within the X-wind framework.

  14. RW Aur A FROM THE X-WIND POINT OF VIEW: GENERAL FEATURES

    Liu, Chun-Fan [Graduate Institute of Astrophysics, National Taiwan University, Taipei 10617, Taiwan (China); Shang, Hsien, E-mail: shang@asiaa.sinica.edu.tw [Theoretical Institute for Advanced Research in Astrophysics (TIARA), Academia Sinica, P.O. Box 23-141, Taipei 10641, Taiwan (China)

    2012-12-20

    In this paper, the RW Aur A microjet is studied from the point of view of X-wind models. The archived Hubble Space Telescope/STIS spectra of the optical forbidden lines [O I], [S II], and [N II] from RW Aur A, taken in Cycle 8 with seven parallel slits along the jet axis, spaced at 0.''07 apart, were analyzed. Images, position-velocity diagrams, and line ratios among the species were constructed, and compared with synthetic observations generated by selected solutions of the X-wind. Prominent features arising in a steady-state X-wind could be identified within the convolved images and position-velocity diagrams, including FWHM and high-velocity peaks on both of the redshifted and blueshifted jets. The well-known asymmetric velocity profiles of the opposite jets were built into the selected models. We discuss model selections within the existing uncertainties of the stellar parameters and inclination angle of the system. In this framework, the mass-loss rates that were inferred to be decreasing along the jet axis in the literature are the results of slowly decreasing excitation conditions and electron density profiles. Despite the apparent asymmetry in the terminal velocities, line intensities and mass-loss rates, the average linear momenta from the opposite sides of the jet are actually balanced. These previously hard-to-explain features of the asymmetric RW Aur A jet system can now be interpreted in a different but self-consistent manner within the X-wind framework.

  15. Study on metallization on RX tubes of fluoroscopic equipment

    Ramos Caballero, L. J.; Angulo Pain, E.; Iborra Oquendo, M. a.; Seguro Fernandez, A.

    2013-01-01

    The PECCRD sets values for the performance of a team of rays x as a function of the total filtration of this (for 80 KV, a total filtration [2.5, 5] mm's to the). However it is recommended to check if the RX tube had metallization by exhaustion (part of anode tungsten evaporates and lining the inside of the envelope of the tube). This effect produces an increase in filtration tube and a decrease in performance. (Author)

  16. Human cultural and related remains from Me Aure Cave (site WMD007), Moindou, New Caledonia

    Grant-Mackie, J.A.; Sand, C.; Valentin, F.; Fitzgerald, B.M.; Richer de Forges, B.

    2013-01-01

    In 1995 a small cave near Me Aure (site WMD007) on the west coast of New Caledonia, about 120 km northwest of Noumea, was excavated and found to contain mainly owl and human midden deposits. Some of the contents have already been documented and the present paper completes the study by reporting the human-related materials, including human bone fragments, pottery sherds, bones of four rodent species, and marine mollusc and crab remains. Each of these material classes are reported separately by the authors responsible for their analysis, and the results and interpretations based on each line of evidence are compared and contrasted. The human bone and pottery data suggest a temporally constrained deposit (2750-2350 BP) that has experienced stratigraphic disturbance. This result raises doubt about the un-mixed nature of the deposit emphasized in earlier publications and it urges instead the conclusion that the Me Aure stratigraphy consists mostly of a redeposited set of horizons. If this conclusion is correct, interpretations already published relying on a fixed chronology, especially about vegetation change and avifauna depletion or early aroid introduction will need to be reconsidered. The site constitutes the first in New Caledonia for which a cave deposit has now been fully analysed. (author). 36 refs., 11 figs., 9 tabs.

  17. The radius of RX Eridani

    Woolley, R.; Dean, J.

    1976-01-01

    Photoelectric observations of the light curves of RX Eri obtained in B, V and I, and radial velocity determinations, are combined to determine the radius by a method originally proposed by van Hoof which avoids matching colours in the rising and falling branches of the light curve and concentrates on the falling branch. The results agree well with those from other stars determined by the normal Baade-Wesselink method, but the method is easier to apply if the colour curve is flat in the falling branch. The parameters found for the star are r 0 = 5.5 Sun, mass = 0.45 Sun, and Msub(v) = + 0sup(m).54. (author)

  18. Chandra resolves the T Tauri binary system RW Aur

    Skinner, Stephen L. [CASA, University of Colorado, Boulder, CO 80309-0389 (United States); Güdel, Manuel, E-mail: stephen.skinner@colorado.edu, E-mail: manuel.guedel@univie.ac.at [Department of Astrophysics, University of Vienna, Türkenschanzstr. 17, A-1180 Vienna (Austria)

    2014-06-20

    RW Aur is a multiple T Tauri system consisting of an early-K type primary (A) and a K5 companion (B) at a separation of 1.''4. RW Aur A drives a bipolar optical jet that is well characterized optically. We present results of a sensitive Chandra observation whose primary objective was to search for evidence of soft extended X-ray emission along the jet, as has been seen for a few other nearby T Tauri stars. The binary is clearly resolved by Chandra and both stars are detected as X-ray sources. The X-ray spectra of both stars reveal evidence for cool and hot plasma. Surprisingly, the X-ray luminosity of the less-massive secondary is at least twice that of the primary and is variable. The disparity is attributed to the primary whose X-ray luminosity is at the low end of the range for classical T Tauri stars of similar mass based on established correlations. Deconvolved soft-band images show evidence for slight outward elongation of the source structure of RW Aur A along the blueshifted jet axis inside the central arcsecond. In addition, a faint X-ray emission peak is present on the redshifted axis at an offset of 1.''2 ± 0.''2 from the star. Deprojected jet speeds determined from previous optical studies are too low to explain this faint emission peak as shock-heated jet plasma. Thus, unless flow speeds in the redshifted jet have been underestimated, other mechanisms such as magnetic jet heating may be involved.

  19. UBV Light Curves of ζ AUR Star 32 Cygni

    Il-Seong Nha

    1992-12-01

    Full Text Available UBV ovservation of ζ Aur star 32 Cyg have been at the Yonsei University Observatory suing the 60-cm Goto reflector and five years, 1988-1992. Observations made during these years cover outside of eclipse phase only. No significant light variation which would represent the secondary eclipse of red supergiant by a hot main sequence star is found. The light levels in three passbands do not show any evidence of the proximate effect of this binary system. Some strong light variations, particularly in U, are discussed with no successful explanation.

  20. Anomalous Eclipses of the Young Star RW Aur A

    Lamzin, S.; Cheryasov, D.; Chuntonov, G.; Dodin, A.; Grankin, K.; Malanchev, K.; Nadzhip, A.; Safonov, B.; Shakhovskoy, D.; Shenavrin, V.; Tatarnikov, A.; Vozyakova, O.

    2017-06-01

    Results of UBVRIJHKLM photometry, VRI polarimetry and optical spectroscopy of a young star RW Aur A obtained during 2010-11 and 2014-16 dimming events are presented. During the second dimming the star decreased its brightness to ΔV >4.5 mag, polarization of its light in I-band was up to 30 %, and color-magnitude diagramm was similar to that of UX Ori type stars. We conclude that the reason of both dimmings is an eclipses of the star by dust screen, but the size of the screen is much larger than in the case of UXORs.

  1. HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin/FAK signaling

    Chen, I-Hua; Shih, Hsin-Chu [Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan (China); Hsieh, Pei-Wen [Graduate Institute of Natural Products, School of Traditional Chinese Medicine, and Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan (China); Chang, Fang-Rong [Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan (China); Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan (China); Wu, Yang-Chang, E-mail: yachwu@mail.cmu.edu [School of Pharmacy, College of Pharmacy, China Medical University, Taichung, Taiwan (China); Wu, Chin-Chung, E-mail: ccwu@kmu.edu.tw [Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan (China); Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80708, Taiwan (China); Research Center for Natural Products and Drug Development, Kaohsiung Medical University, Kaohsiung, Taiwan (China)

    2015-12-01

    Anoikis is defined as apoptosis, which is induced by inappropriate cell–matrix interactions. Cancer cells with anoikis resistance tend to undergo metastasis, and this phenomenon has been reported to be associated with integrin and FAK activity. HPW-RX40 is a derivative of 3,4-methylenedioxy-β-nitrostyrene, which is known to prevent platelet aggregation by inhibition of integrin. In the present study, we investigated the effect of HPW-RX40 on an anoikis-resistant human breast cancer cell line MDA-MB-231. HPW-RX40 inhibited cell aggregation and induced cell death in suspending MDA-MB-231 cells, but had only little effect on the monolayer growth of adherent cells. Analysis of caspase activation and poly (ADP-ribose) polymerase (PARP) cleavage confirmed anoikis in HPW-RX40-treated suspending cancer cells. HPW-RX40 also affected the Bcl-2 family proteins in detached cancer cells. Furthermore, HPW-RX40 inhibited detachment-induced activation of FAK and the downstream phosphorylation of Src and paxillin, but did not affect this pathway in adherent cancer cells. We also found that the expression and activation of β1 integrin in MDA-MB-231 cells were reduced by HPW-RX40. The combination of HPW-RX40 with an EGFR inhibitor led to enhanced anoikis and inhibition of the FAK pathway in breast cancer cells. Taken together, our results suggest that HPW-RX40 restores the anoikis sensitivity in the metastatic breast cancer cells by inhibiting integrin and subsequent FAK activation, and reveal a potential strategy for prevention of tumor metastasis. - Highlights: • The β-nitrostyrene derivative, HPW-RX40, induces anoikis in human breast cancer cells. • HPW-RX40 inhibits the integrin/FAK signaling pathway. • The combination of HPW-RX40 with an EGFR inhibitor leads to enhanced anoikis. • HPW-RX40 may have a potential to prevent the spread of metastatic breast cancer.

  2. HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin/FAK signaling

    Chen, I-Hua; Shih, Hsin-Chu; Hsieh, Pei-Wen; Chang, Fang-Rong; Wu, Yang-Chang; Wu, Chin-Chung

    2015-01-01

    Anoikis is defined as apoptosis, which is induced by inappropriate cell–matrix interactions. Cancer cells with anoikis resistance tend to undergo metastasis, and this phenomenon has been reported to be associated with integrin and FAK activity. HPW-RX40 is a derivative of 3,4-methylenedioxy-β-nitrostyrene, which is known to prevent platelet aggregation by inhibition of integrin. In the present study, we investigated the effect of HPW-RX40 on an anoikis-resistant human breast cancer cell line MDA-MB-231. HPW-RX40 inhibited cell aggregation and induced cell death in suspending MDA-MB-231 cells, but had only little effect on the monolayer growth of adherent cells. Analysis of caspase activation and poly (ADP-ribose) polymerase (PARP) cleavage confirmed anoikis in HPW-RX40-treated suspending cancer cells. HPW-RX40 also affected the Bcl-2 family proteins in detached cancer cells. Furthermore, HPW-RX40 inhibited detachment-induced activation of FAK and the downstream phosphorylation of Src and paxillin, but did not affect this pathway in adherent cancer cells. We also found that the expression and activation of β1 integrin in MDA-MB-231 cells were reduced by HPW-RX40. The combination of HPW-RX40 with an EGFR inhibitor led to enhanced anoikis and inhibition of the FAK pathway in breast cancer cells. Taken together, our results suggest that HPW-RX40 restores the anoikis sensitivity in the metastatic breast cancer cells by inhibiting integrin and subsequent FAK activation, and reveal a potential strategy for prevention of tumor metastasis. - Highlights: • The β-nitrostyrene derivative, HPW-RX40, induces anoikis in human breast cancer cells. • HPW-RX40 inhibits the integrin/FAK signaling pathway. • The combination of HPW-RX40 with an EGFR inhibitor leads to enhanced anoikis. • HPW-RX40 may have a potential to prevent the spread of metastatic breast cancer.

  3. TRX-4 (TolerRx Inc).

    Brown, William M

    2006-04-01

    TolerRx Inc, under license from BTG plc, is developing TRX-4, an anti-CD3 humanized monoclonal antibody for the potential treatment of type 1 diabetes and psoriasis. Phase II trials of the therapeutic antibody in type 1 diabetes have been completed and the company is planning a pivotal phase III trial for this indication. TolerRx is also enrolling psoriasis patients in a phase Ib clinical study of TRX-4. TRX-4 has been awarded Orphan Drug status for recent-onset type 1 diabetes.

  4. RX LAPAN Rocket data Program With Dbase III Plus

    Sauman

    2001-01-01

    The components data rocket RX LAPAN are taken from workshop product and assembling rocket RX. In this application software, the test data are organized into two data files, i.e. test file and rocket file. Besides [providing facilities to add, edit and delete data, this software provides also data manipulation facility to support analysis and identification of rocket RX failures and success

  5. STABLE AND UNSTABLE REGIMES OF MASS ACCRETION ONTO RW AUR A

    Takami, Michihiro; Wei, Yu-Jie; Chou, Mei-Yin; Karr, Jennifer L.; Liu, Hauyu Baobab [Institute of Astronomy and Astrophysics, Academia Sinica, 11F of Astronomy-Mathematics Building, AS/NTU, No.1, Sec. 4, Roosevelt Rd., Taipei 10617, Taiwan, R.O.C. (China); Beck, Tracy L. [Space Telescope Science Institute, 3700 San Martin Dr., Baltimore, MD 21218 (United States); Manset, Nadine [Canada–France–Hawaii Telescope, 65-1238 Mamalahoa Hwy., Kamuela, HI 96743 (United States); Chen, Wen-Ping [Institute of Astronomy, National Central University, Taiwan 320, Taiwan (China); Kurosawa, Ryuichi [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany); Fukagawa, Misato [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); White, Marc [Research School of Astronomy and Astrophysics, The Australian National University, Cotter Rd., Weston, ACT 2611 (Australia); Galván-Madrid, Roberto [Centro de Radioastronomía y Astrofísica, UNAM, Apdo. Postal 3-72 (Xangari), 58089 Morelia, Michoacán, México (Mexico); Pyo, Tae-Soo [Subaru Telescope, 650 North Aohoku Place, Hilo, HI 96720 (United States); Donati, Jean-Francois, E-mail: hiro@asiaa.snica.edu.tw [UPS-Toulouse/CNRS-INSU, Institut de Recherche en Astrophysique et Plańetologie (IRAP) UMR 5277, Toulouse F-31400 (France)

    2016-04-01

    We present monitoring observations of the active T Tauri star RW Aur, from 2010 October to 2015 January, using optical high-resolution (R ≥ 10,000) spectroscopy with Canada–France–Hawaii Telescope/ESPaDOnS. Optical photometry in the literature shows bright, stable fluxes over most of this period, with lower fluxes (by 2–3 mag) in 2010 and 2014. In the bright period our spectra show clear photospheric absorption, complicated variation in the Ca ii λ8542 emission profile shapes, and a large variation in redshifted absorption in the O i λλ7772 and 8446 and He i λ5876 lines, suggesting unstable mass accretion during this period. In contrast, these line profiles are relatively uniform during the faint periods, suggesting stable mass accretion. During the faint periods, the photospheric absorption lines are absent or marginal, and the averaged Li i profile shows redshifted absorption due to an inflow. We discuss (1) occultation by circumstellar material or a companion and (2) changes in the activity of mass accretion to explain the above results, together with near-infrared and X-ray observations from 2011 to 2015. Neither scenario can simply explain all the observed trends, and more theoretical work is needed to further investigate their feasibilities.

  6. Confinement in TPE-RX reversed field pinch

    Yagi, Y.; Bolzonella, T.; Canton, A.

    2001-01-01

    Characteristics of the confinement properties of a reversed field pinch (RFP), the TPE-RX (R/a=1.72/0.45 m, R and a are major and minor radii), are presented for the plasma current, I p of 0.2-0.4 MA. TPE-RX has been operational since 1998, and I p =0.5 MA and duration time of up to 0.1 s have been obtained separately. It is found that I p /N (=12x10 -14 Am, N is the line density) is higher than those of other RFPs and poloidal beta, β p , and energy confinement time, τ E , are 5-10% and 0.5-1 ms, respectively, which are comparable with those of other RFPs of comparable sizes (RFX and MST). Pulsed poloidal current drive has recently been tested and the result has shown a twofold improvement of β p and τ E . The improvement is discussed in terms of the dynamic trajectories in the F-Θ plane, where F and Θ are reversal and pinch parameters, respectively. The global confinement properties are compared between the locked and non-locked discharges, which yields a better understanding of the mode-locking phenomena in RFP plasmas. (author)

  7. The origin of RX J1856.5-3754 and RX J0720.4-3125 - updated using new parallax measurements

    Tetzlaff, N.; Eisenbeiss, T.; Neuhäuser, R.; Hohle, M. M.

    2011-10-01

    RX J1856.5-3754 and RX J0720.4-3125 are the only young isolated radio-quiet neutron stars (NSs) for which trigonometric parallaxes were measured. Due to detection of their thermal emission in X-rays, they are important to study NS cooling and to probe theoretical cooling models. Hence, a precise determination of their age is essential. Recently, new parallax measurements of RX J1856.5-3754 and RX J0720.4-3125 were obtained. Considering that NSs may originate from binary systems that got disrupted due to an asymmetric supernova, we attempt to identify runaway stars which may have been former companions to the NS progenitors. Such an identification would strongly support a particular birth scenario with time and place. We trace back each NS, runaway star and the centres of possible birth associations (assuming that most NSs are ejected directly from their parent association) to find close encounters. The kinematic age is then given by the time since the encounter. We use Monte Carlo simulations to account for observational uncertainties and evaluate the outcome statistically. Using the most recent parallax measurement of 8.16 ± 0.80 mas for RX J1856.5-3754 by Walter et al., we find that it originated in the Upper Scorpius association 0.46 ± 0.05 Myr ago. This kinematic age is slightly larger than the value we reported earlier (0.3 Myr) using the old parallax value of 5.6 ± 0.6 mas by Kaplan. Our result is strongly supported by its current radial velocity which we predict to be 6+19- 20 km s-1. This implies an inclination angle to the line of sight of 88°± 6° consistent with estimates by van Kerkwijk & Kulkarni from the bow shock. No suitable runaway star was found to be a potential former companion of RX J1856.5-3754. Making use of a recent parallax measurement for RX J0720.4-3125 of 3.6 ± 1.6 mas by Eisenbeiss, we find that this NS was possibly born in Trumpler 10 0.85 ± 0.15 Myr ago. This kinematic age is somewhat larger than the one obtained using the old

  8. An UXor among FUors: Extinction-related Brightness Variations of the Young Eruptive Star V582 Aur

    Ábrahám, P.; Kóspál, Á.; Kun, M.; Fehér, O.; Zsidi, G.; Acosta-Pulido, J. A.; Carnerero, M. I.; García-Álvarez, D.; Moór, A.; Cseh, B.; Hajdu, G.; Hanyecz, O.; Kelemen, J.; Kriskovics, L.; Marton, G.; Mező, Gy.; Molnár, L.; Ordasi, A.; Rodríguez-Coira, G.; Sárneczky, K.; Sódor, Á.; Szakáts, R.; Szegedi-Elek, E.; Szing, A.; Farkas-Takács, A.; Vida, K.; Vinkó, J.

    2018-01-01

    V582 Aur is an FU Ori-type young eruptive star in outburst since ∼1985. The eruption is currently in a relatively constant plateau phase, with photometric and spectroscopic variability superimposed. Here we will characterize the progenitor of the outbursting object, explore its environment, and analyze the temporal evolution of the eruption. We are particularly interested in the physical origin of the two deep photometric dips, one that occurred in 2012 and one that is ongoing since 2016. We collected archival photographic plates and carried out new optical, infrared, and millimeter-wave photometric and spectroscopic observations between 2010 and 2018, with a high sampling rate during the current minimum. Besides analyzing the color changes during fading, we compiled multiepoch spectral energy distributions and fitted them with a simple accretion disk model. Based on pre-outburst data and a millimeter continuum measurement, we suggest that the progenitor of the V582 Aur outburst is a low-mass T Tauri star with average properties. The mass of an unresolved circumstellar structure, probably a disk, is 0.04 M ⊙. The optical and near-infrared spectra demonstrate the presence of hydrogen and metallic lines, show the CO band head in absorption, and exhibit a variable Hα profile. The color variations strongly indicate that both the ∼1 yr long brightness dip in 2012 and the current minimum since 2016 are caused by increased extinction along the line of sight. According to our accretion disk models, the reddening changed from A V = 4.5 to 12.5 mag, while the accretion rate remained practically constant. Similarly to the models of the UXor phenomenon of intermediate- and low-mass young stars, orbiting disk structures could be responsible for the eclipses.

  9. A flickering study of nova-like systems KR Aur and UU Aqr

    Dobrotka, A.; Mineshige, S.; Casares, J.

    2012-03-01

    We present a study of the flickering activity in two nova-like systems, KR Aur and UU Aqr. We applied a statistical model of flickering simulations in accretion discs based on turbulent angular momentum transport between two adjacent rings with an exponential distribution of the turbulence dimension scale. The model is based on a steady-state disc model, which is satisfied in the case of hot ionized discs of nova-like cataclysmic variables. Our model successfully fits the observed power-density spectrum of KR Aur with the disc parameter α= 0.10-0.40 and an inner-disc truncation radius in the range Rin= 0.88-1.67 × 109 cm. The exact values depend on the mass-transfer rate in the sense that α decreases and Rin increases with mass-transfer rate. In any case, the inner-disc radius found for KR Aur is considerably smaller than those for quiescent dwarf novae, as predicted by the disc instability model. On the other hand, our simulations fail to reproduce the power-density spectrum of UU Aqr. A tantalizing explanation involves the possible presence of spiral waves, which are expected in UU Aqr because of its low mass ratio but not in KR Aur. In general our model predicts the observed concentration of flickering in the central disc. We explain this by the radial dependence of the angular-momentum gradient.

  10. In situ Micrometeorological Measurements during RxCADRE

    Clements, C. B.; Hiers, J. K.; Strenfel, S. J.

    2009-12-01

    The Prescribed Fire Combustion and Atmospheric Dynamics Research Experiment (RxCADRE) was a collaborative research project designed to fully instrument prescribed fires in the Southeastern United States. Data were collected on pre-burn fuel loads, post burn consumption, ambient weather, in situ atmospheric dynamics, plume dynamics, radiant heat release (both from in-situ and remote sensors), in-situ fire behavior, and select fire effects. The sampling was conducted at Eglin Air Force Base, Florida, and the Joseph W. Jones Ecological Research Center in Newton, Georgia, from February 29 to March 6, 2008. Data were collected on 5 prescribed burns, totaling 4458 acres. The largest aerial ignition totaled 2,290 acres and the smallest ground ignition totaled 104 acres. Quantifying fire-atmospheric interactions is critical for understanding wildland fire dynamics and enhancing modeling of smoke plumes. During Rx-CADRE, atmospheric soundings using radiosondes were made at each burn prior to ignition. In situ micrometeorological measurements were made within each burn unit using five portable, 10-m towers equipped with sonic and prop anemometers, fine-wire thermocouples, and a carbon dioxide probes. The towers were arranged within the burn units to capture the wind and temperature fields as the fire front and plume passed the towers. Due to the interaction of fire lines following ignition, several of the fire fronts that passed the towers were backing fires and thus less intense. Preliminary results indicate that the average vertical velocities associated with the fire front passage were on the order of 3-5 m s-1 and average plume temperatures were on the order of 30-50 °C above ambient. During two of the experimental burns, radiosondes were released into the fire plumes to determine the vertical structure of the plume temperature, humidity, and winds. A radiosonde released into the plume during the burn conducted on 3 March 2008 indicated a definite plume boundary in the

  11. The Potato Nucleotide-binding Leucine-rich Repeat (NLR) Immune Receptor Rx1 Is a Pathogen-dependent DNA-deforming Protein.

    Fenyk, Stepan; Townsend, Philip D; Dixon, Christopher H; Spies, Gerhard B; de San Eustaquio Campillo, Alba; Slootweg, Erik J; Westerhof, Lotte B; Gawehns, Fleur K K; Knight, Marc R; Sharples, Gary J; Goverse, Aska; Pålsson, Lars-Olof; Takken, Frank L W; Cann, Martin J

    2015-10-09

    Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable cells to respond to pathogen attack. Several NLRs act in the nucleus; however, conserved nuclear targets that support their role in immunity are unknown. Previously, we noted a structural homology between the nucleotide-binding domain of NLRs and DNA replication origin-binding Cdc6/Orc1 proteins. Here we show that the NB-ARC (nucleotide-binding, Apaf-1, R-proteins, and CED-4) domain of the Rx1 NLR of potato binds nucleic acids. Rx1 induces ATP-dependent bending and melting of DNA in vitro, dependent upon a functional P-loop. In situ full-length Rx1 binds nuclear DNA following activation by its cognate pathogen-derived effector protein, the coat protein of potato virus X. In line with its obligatory nucleocytoplasmic distribution, DNA binding was only observed when Rx1 was allowed to freely translocate between both compartments and was activated in the cytoplasm. Immune activation induced by an unrelated NLR-effector pair did not trigger an Rx1-DNA interaction. DNA binding is therefore not merely a consequence of immune activation. These data establish a role for DNA distortion in Rx1 immune signaling and define DNA as a molecular target of an activated NLR. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  12. The Potato Nucleotide-binding Leucine-rich Repeat (NLR) Immune Receptor Rx1 Is a Pathogen-dependent DNA-deforming Protein*

    Fenyk, Stepan; Townsend, Philip D.; Dixon, Christopher H.; Spies, Gerhard B.; de San Eustaquio Campillo, Alba; Slootweg, Erik J.; Westerhof, Lotte B.; Gawehns, Fleur K. K.; Knight, Marc R.; Sharples, Gary J.; Goverse, Aska; Pålsson, Lars-Olof; Takken, Frank L. W.; Cann, Martin J.

    2015-01-01

    Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable cells to respond to pathogen attack. Several NLRs act in the nucleus; however, conserved nuclear targets that support their role in immunity are unknown. Previously, we noted a structural homology between the nucleotide-binding domain of NLRs and DNA replication origin-binding Cdc6/Orc1 proteins. Here we show that the NB-ARC (nucleotide-binding, Apaf-1, R-proteins, and CED-4) domain of the Rx1 NLR of potato binds nucleic acids. Rx1 induces ATP-dependent bending and melting of DNA in vitro, dependent upon a functional P-loop. In situ full-length Rx1 binds nuclear DNA following activation by its cognate pathogen-derived effector protein, the coat protein of potato virus X. In line with its obligatory nucleocytoplasmic distribution, DNA binding was only observed when Rx1 was allowed to freely translocate between both compartments and was activated in the cytoplasm. Immune activation induced by an unrelated NLR-effector pair did not trigger an Rx1-DNA interaction. DNA binding is therefore not merely a consequence of immune activation. These data establish a role for DNA distortion in Rx1 immune signaling and define DNA as a molecular target of an activated NLR. PMID:26306038

  13. Design and manufacturing of vacuum vessel of TPE-RX

    Sago, H.; Kaguchi, H.; Orita, J.; Ishigami, Y. [Mitsubishi Heavy Industries Ltd., Kobe (Japan); Urata, K. [Mitsubishi Heavy Industries Ltd. (Japan). Nuclear Energy Systems Engineering Center; Hasegawa, M. [Mitsubishi Electric Co. (Japan). Nuclear Fusion Development; Yagi, Y.; Hirano, Y.; Shimada, T.; Sekine, S.; Sakakita, H. [Electrotechnical Lab. (Japan)

    1998-07-01

    Construction of a new, large reversed field pinch (RFP) machine called TPE-RX was complete at the end of 1997 as a successor of the previous TPE-1RM20 machine at the Electrotechnical Laboratory (ETL). RFP configuration has been successfully obtained in March 1998. This paper introduces structural design and manufacturing of the vacuum vessel of TPE-RX. The support positions were decided by structural analyses. The structural integrity of the vacuum vessel was evaluated by inelastic analyses. (author)

  14. Design and manufacturing of vacuum vessel of TPE-RX

    Sago, H.; Kaguchi, H.; Orita, J.; Ishigami, Y.; Urata, K.

    1998-01-01

    Construction of a new, large reversed field pinch (RFP) machine called TPE-RX was complete at the end of 1997 as a successor of the previous TPE-1RM20 machine at the Electrotechnical Laboratory (ETL). RFP configuration has been successfully obtained in March 1998. This paper introduces structural design and manufacturing of the vacuum vessel of TPE-RX. The support positions were decided by structural analyses. The structural integrity of the vacuum vessel was evaluated by inelastic analyses. (author)

  15. Equalization method for Medipix3RX

    Rinkel, Jean, E-mail: jean.rinkel@lnls.br [Brazilian Synchrotron Light Laboratory (LNLS/CNPEM), Rua Giuseppe Máximo Scolfaro, 10.000, Caixa Postal 6192, 13083-970 Campinas, SP (Brazil); Magalhães, Debora; Wagner, Franz [Brazilian Synchrotron Light Laboratory (LNLS/CNPEM), Rua Giuseppe Máximo Scolfaro, 10.000, Caixa Postal 6192, 13083-970 Campinas, SP (Brazil); Frojdh, Erik; Ballabriga Sune, Rafael [CERN, Route de Meyrin 385, Geneva (Switzerland)

    2015-11-21

    This paper describes a new method of threshold equalization for X-ray detectors based on the Medipix3RX ASIC, using electrical pulses to calibrate and correct for the threshold dispersion between pixels. This method involves a coarse threshold tuning, based on two 8 bits global DACs and which sets the range of variation of the threshold values; and a fine-tuning, based on two 5-bits adjustment DACs per pixel. As our fine-tuning approach is based on a state-of-the-art methodology, our coarse tuning relies on an original theoretical model. This model takes into account the noise level of the ASIC, which varies with temperature and received radiation dose. The experimental results using 300 μm Si sensor and Kα fluorescence of Zn show a global energy resolution improvement of 14% compared to previous equalization methods. We compared these results with the best achievable global energy resolution given by the resolution of individual pixels and concluded that the remaining 14% difference was due to the discretization error limited by the number of equalization bits.

  16. Equalization method for Medipix3RX

    Rinkel, Jean; Wagner, Franz; Frojdh, Erik; Ballabriga Sune, Rafael

    2015-01-01

    This paper describes a new method of threshold equalization for X-ray detectors based on the Medipix3RX ASIC, using electrical pulses to calibrate and correct for the threshold dispersion between pixels. This method involves a coarse threshold tuning, based on two 8 bits global DACs and which sets the range of variation of the threshold values; and a fine-tuning, based on two 5-bits adjustment DACs per pixel. As our fine-tuning approach is based on a state-of-the-art methodology, our coarse tuning relies on an original theoretical model. This model takes into account the noise level of the ASIC, which varies with temperature and received radiation dose. The experimental results using 300 μm Si sensor and Kα fluorescence of Zn show a global energy resolution improvement of 14% compared to previous equalization methods. We compared these results with the best achievable global energy resolution given by the resolution of individual pixels and concluded that the remaining 14% difference was due to the discreti...

  17. AN IONIZED OUTFLOW FROM AB AUR, A HERBIG AE STAR WITH A TRANSITIONAL DISK

    Rodríguez, Luis F.; Zapata, Luis A.; Ortiz-León, Gisela N.; Loinard, Laurent [Centro de Radioastronomía y Astrofísica, UNAM, Apdo. Postal 3-72 (Xangari), 58089 Morelia, Michoacán (Mexico); Dzib, Sergio A. [Max Planck Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany); Macías, Enrique; Anglada, Guillem, E-mail: l.rodriguez@crya.unam.mx [Instituto de Astrofísica de Andalucía (CSIC), Apartado 3004, E-18080 Granada (Spain)

    2014-09-20

    AB Aur is a Herbig Ae star with a transitional disk. Transitional disks present substantial dust clearing in their inner regions, most probably because of the formation of one or more planets, although other explanations are still viable. In transitional objects, accretion is found to be about an order of magnitude smaller than in classical full disks. Since accretion is believed to be correlated with outflow activity, centimeter free-free jets are expected to be present in association with these systems, at weaker levels than in classical protoplanetary (full) systems. We present new observations of the centimeter radio emission associated with the inner regions of AB Aur and conclude that the morphology, orientation, spectral index, and lack of temporal variability of the centimeter source imply the presence of a collimated, ionized outflow. The radio luminosity of this radio jet is, however, about 20 times smaller than that expected for a classical system of similar bolometric luminosity. We conclude that centimeter continuum emission is present in association with stars with transitional disks, but at levels than are becoming detectable only with the upgraded radio arrays. On the other hand, assuming that the jet velocity is 300 km s{sup –1}, we find that the ratio of mass loss rate to accretion rate in AB Aur is ∼0.1, similar to that found for less evolved systems.

  18. Structural design and manufacturing of TPE-RX vacuum vessel

    Sago, H.; Orita, J.; Kaguchi, H.; Ishigami, Y. [Mitsubishi Heavy Ind. Ltd., Kobe (Japan); Urata, K.; Kudough, F. [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan); Hasegawa, M.; Oyabu, I. [Mitsubishi Electric Co., Tokyo (Japan); Yagi, Y.; Sekine, S.; Shimada, T.; Hirano, Y.; Sakakita, H.; Koguchi, H. [Electrotechnical Laboratory, Tsukuba (Japan)

    1999-10-01

    TPE-RX is a newly constructed, large-sized reversed field pinch (RFP) machine installed at the Electrotechnical Laboratory of the Ministry of International Trade and Industry in Japan. This is the third largest RFP in the world. Major and minor radii of the plasma are 1.72 and 0.45 m, respectively. TPE-RX aims to optimize plasma confinement up to 1 MA. RFP plasma configuration was successfully obtained in March 1998. This paper reports the structural design and manufacturing of the vacuum vessel of TPE-RX. The supporting system on the bellows sections of the vessel was designed based on a detailed finite element method. The integrity of the vacuum vessel against a plasma disruption has been confirmed using dynamic inelastic analyses. (orig.)

  19. Structural design and manufacturing of TPE-RX vacuum vessel

    Sago, H.; Orita, J.; Kaguchi, H.; Ishigami, Y.; Urata, K.; Kudough, F.; Hasegawa, M.; Oyabu, I.; Yagi, Y.; Sekine, S.; Shimada, T.; Hirano, Y.; Sakakita, H.; Koguchi, H.

    1999-01-01

    TPE-RX is a newly constructed, large-sized reversed field pinch (RFP) machine installed at the Electrotechnical Laboratory of the Ministry of International Trade and Industry in Japan. This is the third largest RFP in the world. Major and minor radii of the plasma are 1.72 and 0.45 m, respectively. TPE-RX aims to optimize plasma confinement up to 1 MA. RFP plasma configuration was successfully obtained in March 1998. This paper reports the structural design and manufacturing of the vacuum vessel of TPE-RX. The supporting system on the bellows sections of the vessel was designed based on a detailed finite element method. The integrity of the vacuum vessel against a plasma disruption has been confirmed using dynamic inelastic analyses. (orig.)

  20. Evaluation of RxNorm for Medication Clinical Decision Support.

    Freimuth, Robert R; Wix, Kelly; Zhu, Qian; Siska, Mark; Chute, Christopher G

    2014-01-01

    We evaluated the potential use of RxNorm to provide standardized representations of generic drug name and route of administration to facilitate management of drug lists for clinical decision support (CDS) rules. We found a clear representation of generic drug name but not route of administration. We identified several issues related to data quality, including erroneous or missing defined relationships, and the use of different concept hierarchies to represent the same drug. More importantly, we found extensive semantic precoordination of orthogonal concepts related to route and dose form, which would complicate the use of RxNorm for drug-based CDS. This study demonstrated that while RxNorm is a valuable resource for the standardization of medications used in clinical practice, additional work is required to enhance the terminology so that it can support expanded use cases, such as managing drug lists for CDS.

  1. Progress on TSV technology for Medipix3RX chip

    Sarajlić, M.; Pennicard, D.; Smoljanin, S.; Fritzsch, T.; Zoschke, K.; Graafsma, H.

    2017-12-01

    The progress of Through Silicon Via (TSV) technology for Medipix3RX chip done at DESY is presented here. The goal of this development is to replace the wire bonds in X-ray detectors with TSVs, in order to reduce the dead area between detectors. We obtained the first working chips assembled together with Si based sensors for X-ray detection. The 3D integration technology, including TSV, Re-distribution layer deposition, bump bonding to the Si sensor and bump bonding to the carrier PCB, was done by Fraunhofer Institute IZM in Berlin. After assembly, the module was successfully tested by recording background radiation and making X-ray images of small objects. The active area of the Medipix3RX chip is 14.1 mm×14.1 mm or 256×256 pixels. During TSV processing, the Medipix3RX chip was thinned from 775 μm original thickness, to 130 μm. The diameter of the vias is 40 μm, and the pitch between the vias is 120 μm. A liner filling approach was used to contact the TSV with the RDL on the backside of the Medipix3RX readout chip.

  2. Improving Materials Accountancy for Reprocessing using hiRX

    Cipiti, B.; McDaniel, M.; Havrilla, G.

    2015-01-01

    The High Resolution X-ray (hiRX) technology has the potential to replace K-Edge and Hybrid K-Edge Densitometry (HKED) for routine accountability measurements in reprocessing. This technology may significantly reduce plutonium measurement uncertainty in a simpler and less costly instrument. X-ray optics are used to generate monochromatic excitation of a sample and selectively collect emitted X-rays of the target elements. The result is a spectrum with a peak specific to one element with negligible background. Modeling was used to examine how safeguards could be improved through the use of hiRX at existing aqueous reprocessing plants. This work utilized the Separation and Safeguards Performance Model (SSPM), developed at Sandia National Laboratories, to examine how reduced measurement uncertainty decreases the overall inventory difference measurement error. Material loss scenarios were also modelled to determine the effect on detection probability for protracted diversion of nuclear material. Current testing of hiRX is being used to inform the modelling effort, but a 0.1% measurement uncertainty for uranium and plutonium concentration is an optimistic goal based on laboratory results. Modeling results showed that a three-fold improvement in the ability to detect a protracted diversion of plutonium may be possible if the 0.1% uncertainty goal can be achieved. The modelling results will be presented along with a discussion of the current experimental campaign results. In addition, a qualitative cost analysis will be presented to compare the use of hiRX with HKED. (author)

  3. Using the RxNorm web services API for quality assurance purposes.

    Peters, Lee; Bodenreider, Olivier

    2008-11-06

    Auditing large, rapidly evolving terminological systems is still a challenge. In the case of RxNorm, a standardized nomenclature for clinical drugs, we argue that quality assurance processes can benefit from the recently released application programming interface (API) provided by RxNav. We demonstrate the usefulness of the API by performing a systematic comparison of alternative paths in the RxNorm graph, over several thousands of drug entities. This study revealed potential errors in RxNorm, currently under review. The results also prompted us to modify the implementation of RxNav to navigate the RxNorm graph more accurately. The RxNav web services API used in this experiment is robust and fast.

  4. Peroxide Activation for Electrophilic Reactivity by the Binuclear Non-heme Iron Enzyme AurF

    Park, Kiyoung; Li, Ning; Kwak, Yeonju; Srnec, Martin

    2017-01-01

    Binuclear non-heme iron enzymes activate O 2 for diverse chemistries that include oxygenation of organic substrates and hydrogen atom abstraction. This process often involves the formation of peroxo-bridged biferric intermediates, only some of which can perform electrophilic reactions. To elucidate the geometric and electronic structural requirements to activate peroxo reactivity, the active peroxo intermediate in 4-aminobenzoate N-oxygenase (AurF) has been characterized spectroscopically and computationally. A magnetic circular dichroism study of reduced AurF shows that its electronic and geometric structures are poised to react rapidly with O 2 . Nuclear resonance vibrational spectroscopic definition of the peroxo intermediate formed in this reaction shows that the active intermediate has a protonated peroxo bridge. Density functional theory computations on the structure established here show that the protonation activates peroxide for electrophilic/single-electron-transfer reactivity. As a result, this activation of peroxide by protonation is likely also relevant to the reactive peroxo intermediates in other binuclear non-heme iron enzymes.

  5. Multiwavelength analysis of dark matter annihilation and RX-DMFIT

    McDaniel, A.; Jeltema, T.; Profumo, S.; Storm, E.

    2017-01-01

    Dark matter (DM) particles are predicted by several well motivated models to yield Standard Model particles through self-annihilation that can potentially be detected by astrophysical observations. In particular, the production of charged particles from DM annihilation in astrophysical systems that contain magnetic fields yields radio emission through synchrotron radiation and X-ray emission through inverse Compton scattering of ambient photons. We introduce RX-DMFIT, a tool used for calculating the expected secondary emission from DM annihilation. RX-DMFIT includes a wide range of customizable astrophysical and particle parameters and incorporates important astrophysics including the diffusion of charged particles, relevant radiative energy losses, and magnetic field modelling. We demonstrate the use and versatility of RX-DMFIT by analyzing the potential radio and X-ray signals for a variety of DM particle models and astrophysical environments including galaxy clusters, dwarf spheroidal galaxies and normal galaxies. We then apply RX-DMFIT to a concrete example using Segue I radio data to place constraints for a range of assumed DM annihilation channels. For WIMP models with M χ ≤ 100 GeV and assuming weak diffusion, we find that the leptonic μ + μ − and τ + τ − final states provide the strongest constraints, placing limits on the DM particle cross-section well below the thermal relic cross-section, while even for the b b-bar channel we find limits close to the thermal relic cross-section. Our analysis shows that radio emission provides a highly competitive avenue for dark matter searches.

  6. Multiwavelength analysis of dark matter annihilation and RX-DMFIT

    McDaniel, A.; Jeltema, T.; Profumo, S. [Department of Physics, University of California, 1156 High St. Santa Cruz, CA, 95064 (United States); Storm, E., E-mail: alexmcdaniel@ucsc.edu, E-mail: tesla@ucsc.edu, E-mail: profumo@ucsc.edu, E-mail: e.m.storm@uva.nl [GRAPPA, Institute of Physics, Universiteit van Amsterdam Science Park 904, 1098XH Amsterdam (Netherlands)

    2017-09-01

    Dark matter (DM) particles are predicted by several well motivated models to yield Standard Model particles through self-annihilation that can potentially be detected by astrophysical observations. In particular, the production of charged particles from DM annihilation in astrophysical systems that contain magnetic fields yields radio emission through synchrotron radiation and X-ray emission through inverse Compton scattering of ambient photons. We introduce RX-DMFIT, a tool used for calculating the expected secondary emission from DM annihilation. RX-DMFIT includes a wide range of customizable astrophysical and particle parameters and incorporates important astrophysics including the diffusion of charged particles, relevant radiative energy losses, and magnetic field modelling. We demonstrate the use and versatility of RX-DMFIT by analyzing the potential radio and X-ray signals for a variety of DM particle models and astrophysical environments including galaxy clusters, dwarf spheroidal galaxies and normal galaxies. We then apply RX-DMFIT to a concrete example using Segue I radio data to place constraints for a range of assumed DM annihilation channels. For WIMP models with M {sub χ} ≤ 100 GeV and assuming weak diffusion, we find that the leptonic μ{sup +}μ{sup −} and τ{sup +}τ{sup −} final states provide the strongest constraints, placing limits on the DM particle cross-section well below the thermal relic cross-section, while even for the b b-bar channel we find limits close to the thermal relic cross-section. Our analysis shows that radio emission provides a highly competitive avenue for dark matter searches.

  7. An aureobasidin A resistance gene isolated from Aspergillus is a homolog of yeast AUR1, a gene responsible for inositol phosphorylceramide (IPC) synthase activity.

    Kuroda, M; Hashida-Okado, T; Yasumoto, R; Gomi, K; Kato, I; Takesako, K

    1999-03-01

    The AUR1 gene of Saccharomyces cerevisiae, mutations in which confer resistance to the antibiotic aureobasidin A, is necessary for inositol phosphorylceramide (IPC) synthase activity. We report the molecular cloning and characterization of the Aspergillus nidulans aurA gene, which is homologous to AUR1. A single point mutation in the aurA gene of A. nidulans confers a high level of resistance to aureobasidin A. The A. nidulans aurA gene was used to identify its homologs in other Aspergillus species, including A. fumigatus, A. niger, and A. oryzae. The deduced amino acid sequence of an aurA homolog from the pathogenic fungus A. fumigatus showed 87% identity to that of A. nidulans. The AurA proteins of A. nidulans and A. fumigatus shared common characteristics in primary structure, including sequence, hydropathy profile, and N-glycosylation sites, with their S. cerevisiae, Schizosaccharomyces pombe, and Candida albicans counterparts. These results suggest that the aureobasidin resistance gene is conserved evolutionarily in various fungi.

  8. Histochemistry for the research in veterinary science: the legacy of Giuseppe Aureli

    A Lauria

    2009-06-01

    Full Text Available Twenty years ago, on April 24th 1984, Giuseppe Aureli, Founding Member and President of the Italian Society of Histochemistry from 1971 to 1973, Director of the Institute of Anatomy of Domestic Animals, Histology and Embryology and Dean of the School of Veterinary Medicine of the University of Milan, died suddenly and before his time. Following in the footsteps of Carlo Bignardi, he started from the time he was a student, to deal with the research approaches of Maffo Vialli, founder of histochemistry in Italy Head in Milan of a skilled group of scientists, he developed a sound and reliable research school mainly based on the use of ever more advanced histochemical and cytochemical techniques to study, in the extensive area of veterinary science, different problems aimed at developing either basic knowledge or animal production.

  9. Efectos de la hindarina sobre las aurículas aisladas

    Roberto Luis Rojas Martínez

    1997-12-01

    Full Text Available Se presentan los efectos de la hindarina y de la clorpromacina sobre la amplitud y la frecuencia de las contracciones espontáneas de las aurículas aisladas de rata. La hindarina produjo bradicardia moderada y aumento discreto de la amplitud de las contracciones en forma dosis-dependiente, en tanto que la clorpromacina deprimió más intensamente tanto la frecuencia como la amplitud de dichas contracciones. Se descartó una acción colinérgica o beta-bloqueadora en la producción de la bradicardia por la hindarina. Se descartó también una acción cardiotónica de la hindarina en las aurículas aisladas de cobayo deprimidas por solución hipocálcica o por hipoxia. Se sugiere su estudio como antiarrítmico.The effects of hindarine and of chlorpromazine on the amplitude and frequency of the spontaneous contractions of rats' isolated atria are presented. Hindarine produced a moderate bradycardia and a discreet increase of the contractions in a dosage-dependent way. Chlorpromazine caused a greater depression of the frequency and amplitude of these contractions. The cholinergic or beta-blocker action was discarded in the production of bradycardia brought about by hindarine. It was also eliminated a cadiotonic action of hindarine in the isolated atria of guinea pig depressed by hypocalcic solution or by hipoxia. It is suggested its study as an antiarrhythmic.

  10. RX J1548.9+0851, a fossil cluster?

    Eigenthaler, P.; Zeilinger, W. W.

    2012-04-01

    Context. Fossil galaxy groups are spatially extended X-ray sources with X-ray luminosities above L{X, bol ≥ 1042 h50-2} erg s-1 and a central elliptical galaxy dominating the optical, the second-brightest galaxy being at least 2 mag fainter in the R band. Whether these systems are a distinct class of objects resulting from exceptional formation and evolution histories is still unclear, mainly due to the small number of objects studied so far, mostly lacking spectroscopy of group members for group membership confirmation and a detailed kinematical analysis. Aims: To complement the scarce sample of spectroscopically studied fossils down to their faint galaxy populations, the fossil candidate RX J1548.9+0851 (z = 0.072) is studied in this work. Our results are compared with existing data from fossils in the literature. Methods: We use ESO VLT VIMOS multi-object spectroscopy to determine redshifts of the faint galaxy population and study the luminosity-weighted dynamics and luminosity function of the system. The full-spectrum fitting package ULySS is used to determine ages and metallicities of group members. VIMOS imaging data are used to study the morphology of the central elliptical. Results: We identify 40 group members spectroscopically within the central 300 kpc of the system and find 31 additional redshifts from the literature, resulting in a total number of 54 spectroscopically confirmed group members within 1 Mpc. RX J1548.9+0851 is made up of two bright ellipticals in the central region with a magnitude gap of Δm1,2 = 1.34 in the SDSS r' band leaving the definition of RX J1548.9+0851 being a fossil to the assumption of the virial radius. We find a luminosity-weighted velocity dispersion of 568 km s-1 and a mass of 2.5 × 1014 M⊙ for the system confirming previous studies that revealed fossils to be massive. An average mass-to-light ratio of M/L 400 M⊙/L⊙ is derived from the SDSS g', r', and i' bands. The central elliptical is well-fitted by a pure de

  11. Home Rx: The Health Benefits of Home Performance

    Wilson, Jonathan [National Center for Healthy Housing (NCHH), Columbia, MD (United States); Jacobs, David [National Center for Healthy Housing (NCHH), Columbia, MD (United States); Reddy, Amanda [National Center for Healthy Housing (NCHH), Columbia, MD (United States); Tohn, Ellen [Tohn Environmental Strategies, Wayland, MA (United States); Cohen, Jonathan [Dept. of Energy (DOE), Washington DC (United States); Jacobsohn, Ely [Dept. of Energy (DOE), Washington DC (United States)

    2016-12-01

    Evidence in a new, groundbreaking U.S. Department of Energy report, Home Rx: The Health Benefits of Home Performance, shows that home performance upgrades can improve the quality of a home’s indoor environment by reducing the prevalence of harmful indoor air pollutants and contaminants. Until recently, no systematic review of this evidence had been conducted, limiting full understanding of the link between home performance and health. This new report summarizes current knowledge and identifies research gaps. The design characteristics and results of each of the 40 studies considered in the report are summarized in a searchable matrix.

  12. LINES

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  13. Aria de pixel: riprodutibilità aurática digitale Ar de pixel: reprodutibilidade aurática digital Pixel air: digital auratic reprodutibility

    Mássimo Canevacci

    2010-04-01

    Full Text Available Il saggio parte dalla riflessione del testo Writing Culture di Clifford-Marcus. Dopo più di 20 anni, è possibile verificare come questa critica, anziché aprire verso il futuro, ha chiuso una fase della mono-scrittura etnografica basata sul concetto di retorica e autorità. Già nella metà degli anni '80 stavano nascendo forme compositive multi-linguistiche sperimentali che applicavano una "etnografia indisciplinata" a design, architettura, pubblicità, musica, cinema, web. Si apre la sfida per una università non solo basata su Facoltà territoriali. Diverse modalità di comunicare attraverso il digitale mescolano e sincretizzano le visioni dualistiche di Benjamin su aura e riproducibilità. La mia prospettiva finale è la riproducibilità auratica digitale.Este artigo parte da reflexão sobre o texto Culture de.i Clifford-Marcus. Após 20 anos de sua publicação, é possível verificar como a crítica feita por este autor fecou uma fase da mono-escritura etnográfica baseana no conceito de retórica e autoridade. Já na metade dos anos 80 estavam nascendo formas compositivas multi-linguísticas experimentais que aplicavam um "etnografia indisciplinada" ao design, arquitetura, publicidade, música, cinema, web, abrindo uma via para universidades não somente baseadas sobre faculdades territoriais. Diversas modalidades de comunicação são digitalmente mixadas, sincretizando o dualimsno de Benjamin sobre aura e repordutibilidade. A minha perspectiva final é a reprodutibilidade aurática digital.My essay starts from a reflection on Clifford-Marcus's Writing Culture. After more than 20 years, it is possible to verify that such a critique - instead of opening toward the future - was going to close to the traditional ethnographic writing based on rhetoric and authority. In the middle of the 80's, were spreading experimental compositive patterns, applying an "undisciplined ethnography" to design, architecture, advertising, music, cinema and web

  14. The Continued Spectral Evolution of the Neutron Star RX J0720.4-3125

    Vink, Jacco; de Vries, Cor P.; Méndez, Mariano; Verbunt, Frank

    2004-01-01

    We observed the isolated neutron star RX J0720.4-3125 with Chandra's Low Energy Transmission Grating Spectrometer, following the XMM-Newton discovery of the long-term spectral evolution of this source. The new observation shows that the spectrum of RX J0720.4-3125 has continued to change in the

  15. Tx-Rx Isolation Exploiting Tunable Balanced-Unbalanced Antennas Architecture

    Tatomirescu, Alexandru; Alrabadi, Osama; Pedersen, Gert Frølund

    2012-01-01

    The duplex filter is probably still the most expensive component in mobile handsets for the significant Transmitter (Tx) — Receiver (Rx) isolation required. This paper suggests to relax or even replace the duplex filter by equipping the Tx and the Rx with two separate antennas. The two antennas a...

  16. La voix off au féminin : Hiroshima mon amour et Aurélia Steiner

    Jennifer Cazenave

    2011-07-01

    Full Text Available Une étude comparée du grand film moderne d’Alain Resnais, Hiroshima mon amour (1959, et du dyptique de Marguerite Duras, Aurélia Steiner (1979, laisse entrevoir une filiation entre deux films que vingt ans séparent et où s’entrecroisent un certain nombre de fils conducteurs : le lieu et la parole ; l’histoire et la mémoire ; la voix-off au féminin et l’irreprésentable. Il s’agira donc de penser ces deux œuvres cinématographiques à partir du rapport entre le parler féminin et la représentation du passé, soit la tonte des femmes au moment de la libération dans Hiroshima mon amour, soit l’extermination des Juifs d’Europe dans Aurélia Steiner.

  17. Conceptos espaciales en una 'political ecology' de extractivismo aurífero, partiendo del caso de Marmato, Colombia

    Pignolet, Thierry

    2017-01-01

    Este papel es un trabajo sobre la apropriación de conceptos espaciales en la definición del problema de investigación doctoral (sobre una 'political ecology' de extractivismo aurífero, partiendo del caso de Marmato, en Colombia), en el contexto del Seminario complementario I del Doctorado en ciencias sociales (semestre 2017-2) de la Universidad de Antioquia (UdeA), Colombia.

  18. AN ORDERED MAGNETIC FIELD IN THE PROTOPLANETARY DISK OF AB Aur REVEALED BY MID-INFRARED POLARIMETRY

    Li, Dan; Pantin, Eric; Telesco, Charles M.; Zhang, Han; Barnes, Peter J.; Mariñas, Naibí [Department of Astronomy, University of Florida, 211 Bryant Space Science Center, FL 32611 (United States); Wright, Christopher M. [School of Physical, Environmental, and Mathematical Sciences, University of New South Wales, Canberra, ACT 2610 (Australia); Packham, Chris, E-mail: d.li@ufl.edu [Physics and Astronomy Department, University of Texas at San Antonio, 1 UTSA Circle, San Antonio, TX 78249 (United States)

    2016-11-20

    Magnetic fields ( B -fields) play a key role in the formation and evolution of protoplanetary disks, but their properties are poorly understood due to the lack of observational constraints. Using CanariCam at the 10.4 m Gran Telescopio Canarias, we have mapped out the mid-infrared polarization of the protoplanetary disk around the Herbig Ae star AB Aur. We detect ∼0.44% polarization at 10.3 μ m from AB Aur's inner disk ( r  < 80 au), rising to ∼1.4% at larger radii. Our simulations imply that the mid-infrared polarization of the inner disk arises from dichroic emission of elongated particles aligned in a disk B -field. The field is well ordered on a spatial scale, commensurate with our resolution (∼50 au), and we infer a poloidal shape tilted from the rotational axis of the disk. The disk of AB Aur is optically thick at 10.3 μ m, so polarimetry at this wavelength is probing the B -field near the disk surface. Our observations therefore confirm that this layer, favored by some theoretical studies for developing magneto-rotational instability and its resultant viscosity, is indeed very likely to be magnetized. At radii beyond ∼80 au, the mid-infrared polarization results primarily from scattering by dust grains with sizes up to ∼1 μ m, a size indicating both grain growth and, probably, turbulent lofting of the particles from the disk mid-plane.

  19. Far Ultraviolet Spectroscopy of Three Long Period Nova-Like Variables, V363 Aur, AC Cnc and RZ Gru

    Bisol, Alexandra; Sion, E. M.

    2011-01-01

    We have selected three nova-like variables: V363 Aur, RZ Gru and AC Cnc, all of which are UX UMa types, having similar orbital periods well beyond the 3 to 4 hour range where most nova-likes are found. All should have very similar secondary stars given the fact that they their physical parameters are so similar. V363 Aur is a bona fide SW Sex star, and AC Cnc is a probable one, while RZ Gru is not a member of the SW Sex subclass. Our objective is to carry out the first synthetic spectral analysis of far ultraviolet spectra of the three systems using state-of-the-art models both of accretion disks and photospheres. Therefore we shall compare the distances we obtain from the best fitting synthetic spectral models to other distance estimates in the literature. We present model-derived accretion rates and distances for all three systems. The FUV flux range of RZ Gru and V363 Aur is dominated by radiation from an optically thick, steady state, accretion but for AC Cnc, we find that a hot white dwarf accounts for 70% of the FUV flux. We compare the FUV characteristics and physical properties of these three long period nova-like systems to the properties of other nova-likes at shorter periods. This work was supported in part by NSF grant AST0807892 to Villanova University.

  20. Constraining the Movement of the Spiral Features and the Locations of Planetary Bodies Within the AB Aur System

    Lomax, Jamie R.; Wisniewski, John P.; Grady, Carol A.; McElwain, Michael W.; Hashimoto, Jun; Kudo, Tomoyuki; Kusakabe, Nobuhiko; Okamoto, Yoshiko K.; Fukagawa, Misato; Abe, Lyu

    2016-01-01

    We present a new analysis of multi-epoch, H-band, scattered light images of the AB Aur system. We use a Monte Carlo radiative transfer code to simultaneously model the systems spectral energy distribution (SED) and H-band polarized intensity (PI) imagery. We find that a disk-dominated model, as opposed to one that is envelope dominated, can plausibly reproduce AB Aurs SED and near-IR imagery. This is consistent with previous modeling attempts presented in the literature and supports the idea that at least a subset of AB Aurs spirals originate within the disk. In light of this, we also analyzed the movement of spiral structures in multi-epoch H-band total light and PI imagery of the disk. We detect no significant rotation or change in spatial location of the spiral structures in these data, which span a 5.8-year baseline. If such structures are caused by disk planet interactions, the lack of observed rotation constrains the location of the orbit of planetary perturbers to be 47 au.

  1. A RESOLVED NEAR-INFRARED IMAGE OF THE INNER CAVITY IN THE GM Aur TRANSITIONAL DISK

    Oh, Daehyeon; Yang, Yi [Department of Astronomical Science, SOKENDAI (The Graduate University for Advanced Studies), 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan); Hashimoto, Jun; Kusakabe, Nobuhiko [Astrobiology Center of NINS 2-21-1, Osawa, Mitaka, Tokyo, 181-8588 (Japan); Carson, Joseph C. [Department of Physics and Astronomy, College of Charleston 66 George Street, Charleston, SC 29424 (United States); Janson, Markus [Department of Astronomy, Stockholm University, AlbaNova University Center SE-106 91 Stockholm (Sweden); Kwon, Jungmi; Nakagawa, Takao [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency 3-1-1 Yoshinodai, Chuo, Sagamihara, Kanagawa 252-5210 (Japan); Mayama, Satoshi [The Center for the Promotion of Integrated Sciences, SOKENDAI (The Graduate University for Advanced Studies), Shonan International Village, Hayama-cho, Miura-gun, Kanagawa 240-0193 (Japan); Uyama, Taichi [Department of Astronomy, The University of Tokyo 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033 (Japan); Kudo, Tomoyuki; Currie, Thayne [Subaru Telescope, National Astronomical Observatory of Japan 650 North A’ohoku Place, Hilo, HI 96720 (United States); Abe, Lyu [Laboratoire Lagrange (UMR 7293), Universite de Nice-Sophia Antipolis, CNRS, Observatoire de la Coted’azur 28 avenue Valrose, F-06108 Nice Cedex 2 (France); Akiyama, Eiji [National Astronomical Observatory of Japan 2-21-1, Osawa, Mitaka, Tokyo, 181-8588 (Japan); Brandner, Wolfgang [Max Planck Institute for Astronomy, Köonigstuhl 17, D-69117 Heidelberg (Germany); Brandt, Timothy D.; Feldt, Markus [Astrophysics Department, Institute for Advanced Study Princeton, NJ (United States); Goto, Miwa [Universitats-Sternwarte Munchen, Ludwig-Maximilians-Universitat, Scheinerstr. 1, D-81679 Munchen (Germany); Grady, Carol A. [Exoplanets and Stellar Astrophysics Laboratory, Code 667, Goddard Space Flight Center Greenbelt, MD 20771 (United States); and others

    2016-11-01

    We present high-contrast H -band polarized intensity (PI) images of the transitional disk around the young solar-like star GM Aur. The near-infrared direct imaging of the disk was derived by polarimetric differential imaging using the Subaru 8.2 m Telescope and HiCIAO. An angular resolution and an inner working angle of 0.″07 and r ∼ 0.″05, respectively, were obtained. We clearly resolved a large inner cavity, with a measured radius of 18 ± 2 au, which is smaller than that of a submillimeter interferometric image (28 au). This discrepancy in the cavity radii at near-infrared and submillimeter wavelengths may be caused by a 3–4 M {sub Jup} planet about 20 au away from the star, near the edge of the cavity. The presence of a near-infrared inner cavity is a strong constraint on hypotheses for inner cavity formation in a transitional disk. A dust filtration mechanism has been proposed to explain the large cavity in the submillimeter image, but our results suggest that this mechanism must be combined with an additional process. We found that the PI slope of the outer disk is significantly different from the intensity slope obtained from HST /NICMOS, and this difference may indicate the grain growth process in the disk.

  2. A K/Ka band radiating element for Tx/Rx phased array

    Sandhu, Ali Imran; Arnieri, E.; Amendola, G.; Boccia, L.; Meniconi, E.; Ziegler, V.

    2017-01-01

    The paper presents a K/Ka band radiating element for TX/RX phased arrays. Dual band operations is obtained using a single radiating surface: a novel radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The array elements are optimized to scan the beam in excess of 50° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  3. Analysis of B chromosome nondisjunction induced by the r-X1 deficiency in maize.

    Tseng, Shih-Hsuan; Peng, Shu-Fen; Cheng, Ya-Ming

    2017-11-20

    The maize B chromosome typically undergoes nondisjunction during the second microspore division. For normal A chromosomes, the r-X1 deficiency in maize can induce nondisjunction during the second megaspore and first microspore divisions. However, it is not known whether the r-X1 deficiency also induces nondisjunction of the maize B chromosome during these cell divisions. To answer this question, chromosome numbers were determined in the progeny of r-X1/R-r female parents carrying two B chromosomes. Some of the r-X1-lacking progeny (21.2%) contained zero or two B chromosomes. However, a much higher percentage of the r-X1-containing progeny (43.4%) exhibited zero or two B chromosomes, but none displayed more than two B chromosomes. Thus, the results indicated that the r-X1 deficiency could also induce nondisjunction of the B chromosome during the second megaspore division; moreover, the B chromosome in itself could undergo nondisjunction during the same division. In addition, pollen grains from plants with two B chromosomes lacking or exhibiting the r-X1 deficiency were compared via pollen fluorescence in situ hybridization (FISH) using a B chromosome-specific probe. The results revealed that the r-X1 deficiency could induce the occurrence of B chromosome nondisjunction during the first microspore division and that the B chromosome in itself could undergo nondisjunction during the same division at a lower frequency. Our data shed more light on the behavior of the maize B chromosome during cell division.

  4. A K/Ka band radiating element for Tx/Rx phased array

    Sandhu, Ali Imran

    2017-01-20

    The paper presents a K/Ka band radiating element for TX/RX phased arrays. Dual band operations is obtained using a single radiating surface: a novel radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The array elements are optimized to scan the beam in excess of 50° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  5. Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo.

    Reinhardt, Robert; Centanin, Lázaro; Tavhelidse, Tinatini; Inoue, Daigo; Wittbrodt, Beate; Concordet, Jean-Paul; Martinez-Morales, Juan Ramón; Wittbrodt, Joachim

    2015-06-03

    Transcriptional networks defining stemness in adult neural stem cells (NSCs) are largely unknown. We used the proximal cis-regulatory element (pCRE) of the retina-specific homeobox gene 2 (rx2) to address such a network. Lineage analysis in the fish retina identified rx2 as marker for multipotent NSCs. rx2-positive cells located in the peripheral ciliary marginal zone behave as stem cells for the neuroretina, or the retinal pigmented epithelium. We identified upstream regulators of rx2 interrogating the rx2 pCRE in a trans-regulation screen and focused on four TFs (Sox2, Tlx, Gli3, and Her9) activating or repressing rx2 expression. We demonstrated direct interaction of the rx2 pCRE with the four factors in vitro and in vivo. By conditional mosaic gain- and loss-of-function analyses, we validated the activity of those factors on regulating rx2 transcription and consequently modulating neuroretinal and RPE stem cell features. This becomes obvious by the rx2-mutant phenotypes that together with the data presented above identify rx2 as a transcriptional hub balancing stemness of neuroretinal and RPE stem cells in the adult fish retina. © 2015 The Authors. Published under the terms of the CC BY NC ND 4.0 license.

  6. Los impactos ambientales y medidas de remediación en las cuencas auríferas de caychive y huaypetue madre de dios

    Gutierrez Orozco, Niverción Hugo; Gutierrez Orozco, Niverción Hugo

    2002-01-01

    Las microcuencas auríferas de los ríos Caychive y Huaypetue - Madre de Dios, constituyen una zona donde la minería aurífera aluvial, a partir de la última década, se ha desarrollado intensa y desordenadamente a nivel de la pequeña minería, sin el adecuado uso de técnicas mineras que conduzcan a preservar el medio ambiente. Las operaciones de explotación y concentración de gravas auríferas han dado lugar a la degradación y contaminación de los principales factores ambientales, bajo la forma...

  7. Probing the Cold Dust Emission in the AB Aur Disk: A Dust Trap in a Decaying Vortex?

    Fuente, Asunción; Baruteau, Clément; Neri, Roberto; Carmona, Andrés; Agúndez, Marcelino; Goicoechea, Javier R; Bachiller, Rafael; Cernicharo, José; Berné, Olivier

    2017-09-01

    One serious challenge for planet formation is the rapid inward drift of pebble-sized dust particles in protoplanetary disks. Dust trapping at local maxima in the disk gas pressure has received much theoretical attention but still lacks observational support. The cold dust emission in the AB Aur disk forms an asymmetric ring at a radius of about 120 au, which is suggestive of dust trapping in a gas vortex. We present high spatial resolution (0".58×0".78 ≈ 80×110 au) NOEMA observations of the 1.12 mm and 2.22 mm dust continuum emission from the AB Aur disk. Significant azimuthal variations of the flux ratio at both wavelengths indicate a size segregation of the large dust particles along the ring. Our continuum images also show that the intensity variations along the ring are smaller at 2.22 mm than at 1.12 mm, contrary to what dust trapping models with a gas vortex have predicted. Our two-fluid (gas+dust) hydrodynamical simulations demonstrate that this feature is well explained if the gas vortex has started to decay due to turbulent diffusion, and dust particles are thus losing the azimuthal trapping on different timescales depending on their size. The comparison between our observations and simulations allows us to constrain the size distribution and the total mass of solid particles in the ring, which we find to be of the order of 30 Earth masses, enough to form future rocky planets.

  8. THE FEASIBILITY OF VILLAGE FOREST PROGRAM IN TANJUNG AUR II VILLAGE, PINO RAYA SUBDISTRICT, SOUTH BENGKULU REGENCY

    Desmantoro

    2016-08-01

    Full Text Available A feasibility study toward the prerequisite conditions is required for the successful implementation of the Village Forest program in Tanjung Aur II Village. This study aims to: 1 identify bio-geophysical conditions of the work area; 2 analyze the conditions of sosioeconomic-cultural society/institutional; 3 analyze the support of stakeholders; and 4 formulate appropriate implementation strategies. The study was using survey method and qualitative studies with multiple analysis techniques. The results showed that: 1 the biogeophysical conditions was eligible and suitable to be proposed as village forest working area; 2 conditions of socio-economic-cultural communities enable to form village forest management institution, through collaboration between state forest encroachers and the villager representatives; 3 stakeholders were ready to provide support facilitation and assistance according to their capacity and capabilities. Key stakeholder were among others BPDAS Ketahun, Dishut Provinsi Bengkulu, Dishut ESDM Bengkulu Selatan, NGOs Ulayat, and officials of the Village; 4 the implementation strategy of village forest program that suitable for Tanjung Aur II was a competitive strategy or diversification (S-T strategy, with the main priority of the strategy, among others by seeking and asking for support from relevant stakeholders or other parties who had capacity and capability to undertake facilitation and assistance.

  9. Probing the Cold Dust Emission in the AB Aur Disk: A Dust Trap in a Decaying Vortex?

    Fuente, Asunción; Bachiller, Rafael [Observatorio Astronómico Nacional (OAN, IGN), Apdo 112, E-28803 Alcalá de Henares (Spain); Baruteau, Clément; Carmona, Andrés; Berné, Olivier [IRAP, Université de Toulouse, CNRS, UPS, Toulouse (France); Neri, Roberto [Institut de Radioastronomie Millimétrique (IRAM), 300 rue de la Piscine, F-38406 Saint Martin d’Hères (France); Agúndez, Marcelino; Goicoechea, Javier R.; Cernicharo, José, E-mail: a.fuente@oan.es [Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), E-28049 Cantoblanco, Madrid (Spain)

    2017-09-01

    One serious challenge for planet formation is the rapid inward drift of pebble-sized dust particles in protoplanetary disks. Dust trapping at local maxima in the disk gas pressure has received much theoretical attention but still lacks observational support. The cold dust emission in the AB Aur disk forms an asymmetric ring at a radius of about 120 au, which is suggestive of dust trapping in a gas vortex. We present high spatial resolution (0.″58 × 0.″78 ≈ 80 × 110 au) NOEMA observations of the 1.12 mm and 2.22 mm dust continuum emission from the AB Aur disk. Significant azimuthal variations of the flux ratio at both wavelengths indicate a size segregation of the large dust particles along the ring. Our continuum images also show that the intensity variations along the ring are smaller at 2.22 mm than at 1.12 mm, contrary to what dust trapping models with a gas vortex have predicted. Our two-fluid (gas+dust) hydrodynamical simulations demonstrate that this feature is well explained if the gas vortex has started to decay due to turbulent diffusion, and dust particles are thus losing the azimuthal trapping on different timescales depending on their size. The comparison between our observations and simulations allows us to constrain the size distribution and the total mass of solid particles in the ring, which we find to be of the order of 30 Earth masses, enough to form future rocky planets.

  10. 'Political ecology' de extractivismos auríferos en Marmato, Colombia: Problématique et théorie-méthodologie de l'investigation

    Pignolet, Thierry

    2017-01-01

    Este papel es el trabajo final de un seminario de profundización del doctorado en ciencias sociales de la Universidad de Antioquia (Colombia). Expone la problemática y la teoría-metodología de una investigación doctoral sobre una 'political ecology' de extractivismo aurífero, partiendo del caso de Marmato, en Colombia.

  11. Sequence alterations in RX in patients with microphthalmia, anophthalmia, and coloboma

    London, Nikolas J.S.; Kessler, Patricia; Williams, Bryan; Pauer, Gayle J.; Hagstrom, Stephanie A.

    2009-01-01

    Purpose Microphthalmia, anophthalmia, and coloboma are ocular malformations with a significant genetic component. Rx is a homeobox gene expressed early in the developing retina and is important in retinal cell fate specification as well as stem cell proliferation. We screened a group of 24 patients with microphthalmia, coloboma, and/or anophthalmia for RX mutations. Methods We used standard PCR and automated sequencing techniques to amplify and sequence each of the three RX exons. Patients’ charts were reviewed for clinical information. The pathologic impact of the identified sequence variant was analyzed by computational methods using PolyPhen and PMut algorithms. Results In addition to the polymorphisms we identified a single patient with coloboma having a heterozygous nucleotide change (g.197G>C) in the first exon that results in a missense mutation of arginine to threonine at amino acid position 66 (R66T). In silico analysis predicted R66T to be a deleterious mutation. Conclusions Sequence variations in RX are uncommon in patients with congenital ocular malformations, but may play a role in disease pathogenesis. We observed a missense mutation in RX in a patient with a small, typical chorioretinal coloboma, and postulate that the mutation is responsible for the patient’s phenotype. PMID:19158959

  12. Mapping Partners Master Drug Dictionary to RxNorm using an NLP-based approach.

    Zhou, Li; Plasek, Joseph M; Mahoney, Lisa M; Chang, Frank Y; DiMaggio, Dana; Rocha, Roberto A

    2012-08-01

    To develop an automated method based on natural language processing (NLP) to facilitate the creation and maintenance of a mapping between RxNorm and a local medication terminology for interoperability and meaningful use purposes. We mapped 5961 terms from Partners Master Drug Dictionary (MDD) and 99 of the top prescribed medications to RxNorm. The mapping was conducted at both term and concept levels using an NLP tool, called MTERMS, followed by a manual review conducted by domain experts who created a gold standard mapping. The gold standard was used to assess the overall mapping between MDD and RxNorm and evaluate the performance of MTERMS. Overall, 74.7% of MDD terms and 82.8% of the top 99 terms had an exact semantic match to RxNorm. Compared to the gold standard, MTERMS achieved a precision of 99.8% and a recall of 73.9% when mapping all MDD terms, and a precision of 100% and a recall of 72.6% when mapping the top prescribed medications. The challenges and gaps in mapping MDD to RxNorm are mainly due to unique user or application requirements for representing drug concepts and the different modeling approaches inherent in the two terminologies. An automated approach based on NLP followed by human expert review is an efficient and feasible way for conducting dynamic mapping. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Peculiar Velocity Constraints from Five-band SZ Effect Measurements toward RX J1347.5-1145 with MUSIC and Bolocam from the CSO

    Sayers, Jack; Zemcov, Michael; Glenn, Jason; Golwala, Sunil R.; Maloney, Philip R.; Siegel, Seth R.; Wheeler, Jordan; Bockstiegel, Clint; Brugger, Spencer; Czakon, Nicole G.; Day, Peter K.; Downes, Thomas P.; Duan, Ran P.; Gao, Jiansong; Hollister, Matthew I.; Lam, Albert; LeDuc, Henry G.; Mazin, Benjamin A.; McHugh, Sean G.; Miller, David A.; Mroczkowski, Tony K.; Noroozian, Omid; Nguyen, Hien T.; Radford, Simon J. E.; Schlaerth, James A.; Vayonakis, Anastasios; Wilson, Philip R.; Zmuidzinas, Jonas

    2016-04-01

    We present Sunyaev-Zel’dovich (SZ) effect measurements from wide-field images toward the galaxy cluster RX J1347.5-1145 obtained from the Caltech Submillimeter Observatory with the Multiwavelength Submillimeter Inductance Camera at 147, 213, 281, and 337 GHz and with Bolocam at 140 GHz. As part of our analysis, we have used higher frequency data from Herschel-SPIRE and previously published lower frequency radio data to subtract the signal from the brightest dusty star-forming galaxies behind RX J1347.5-1145 and from the AGN in RX J1347.5-1145’s BCG. Using these five-band SZ effect images, combined with X-ray spectroscopic measurements of the temperature of the intra-cluster medium (ICM) from Chandra, we constrain the ICM optical depth to be {τ }{{e}}={7.33}-0.97+0.96× {10}-3 and the ICM line of sight peculiar velocity to be {v}{pec}=-{1040}-840+870 km s-1. The errors for both quantities are limited by measurement noise rather than calibration uncertainties or astrophysical contamination, and significant improvements are possible with deeper observations. Our best-fit velocity is in good agreement with one previously published SZ effect analysis and in mild tension with the other, although some or all of that tension may be because that measurement samples a much smaller cluster volume. Furthermore, our best-fit optical depth implies a gas mass slightly larger than the Chandra-derived value, implying the cluster is elongated along the line of sight.

  14. Information Rx Program Requires More Promotion, More Support and Some Adjustment. A Review of: Meeks, K. (2009. Information Rx: Promotion and utilization by Georgia librarians and the Georgia American College of Physicians. Journal of Consumer Health on the Internet, 13, 129-134.

    Matthew Thomas

    2010-12-01

    materials, and 12 reported helping patrons look for information on MedlinePlus ‘‘prescribed’’ to them by their doctors. Responses to the open-ended interview questions given to the four interviewed librarians were mixed regarding receipt of program materials, negative regarding the effectiveness of the program, and reported no awareness of any patrons having been helped with information “prescriptions.” To improve the program’s success, the author suggested steps such as providing promotional information on the MedlinePlus site, better integration between MedlinePlus and Information Rx, involving librarians somehow in the process as a whole given their ability to help users navigate and understand MedlinePlus, and marketed more to nurses given their front-line responsibilities.Conclusion – Although the program is somewhat useful, Information Rx has not been promoted or supported sufficiently. Information needs to be linked on the MedlinePlus website, clarification of the program and that it is available at no charge should be emphasized. Librarians should be involved and the target audience may need to be changed to include nurses.

  15. Medipix3RX: Characterizing the Medipix3 Redesign With Synchrotron Radiation

    Gimenez, Eva N; Blaj, Gabriel; Campbell, Michael; Dolbnya, Igor; Frodjh, Erik; Horswell, Ian; Llopart, Xavier; Marchal, Julien; McGrath, John; Omar, David; Plackett, Richard; Sawhney, Kawal; Tartoni, Nicola

    2015-01-01

    The Medipix3RX is the latest version of the Medipix3 photon counting ASICs, which implements two new operational modes, with respect to the Medipix2 ASIC, aimed at eliminating charge shared events (referred to as Charge Summing Mode (CSM)) and at providing spectroscopic information (referred to as Colour Mode (CM)). The Medipix3RX is a redesign of the Medipix3v0 ASIC and corrects for the underperformance of CSM features observed in the previous version. This paper presents the results from synchrotron X-rays tests to evaluate the Medipix3RX ASIC performance. The newly implemented CSM algorithm eliminates the charge sharing effect at the same time as allocating the event to the readout pixel corresponding to the sensor pixel where the X-ray photon impinged. The new pixel trimming circuit led to a reduced dispersion between pixels. Further results of the linearity for all the gain modes, energy resolution and pixel uniformity are also presented.

  16. Radiating Elements for Shared Aperture Tx/Rx Phased Arrays at K/Ka Band

    Sandhu, Ali Imran; Arnieri, E.; Amendola, Giandomenico; Boccia, L.; Meniconi, Erika; Ziegler, Volker

    2016-01-01

    A dual band, Tx/Rx, self-diplexing phased array is presented. The antenna has been designed to cover Tx/Rx satellite communications at K/Ka band with a frequency ratio 1.5:1. To obtain dual band operations with a single radiating surface, a novel dual band radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The proposed configuration reduces the number of radiating elements required by other solutions while avoiding the insurgence of grating lobes. The tightly packed arrangement of the elements poses many integration issues, which are solved with a novel integration technique. The array elements are optimized to scan the beam in excess of ° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  17. Radiating Elements for Shared Aperture Tx/Rx Phased Arrays at K/Ka Band

    Sandhu, Ali Imran

    2016-04-11

    A dual band, Tx/Rx, self-diplexing phased array is presented. The antenna has been designed to cover Tx/Rx satellite communications at K/Ka band with a frequency ratio 1.5:1. To obtain dual band operations with a single radiating surface, a novel dual band radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The proposed configuration reduces the number of radiating elements required by other solutions while avoiding the insurgence of grating lobes. The tightly packed arrangement of the elements poses many integration issues, which are solved with a novel integration technique. The array elements are optimized to scan the beam in excess of ° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  18. Design of equilibrium field control coil system of TPE-RX

    Sato, F.; Hasegawa, M.; Yamane, M.; Oyabu, I.; Urata, K.; Kudough, F. [Mitsubishi Fusion Center, Chiyoda-ku, Tokyo (Japan); Minato, T.; Kiryu, A.; Takagi, S.; Kuno, K.; Sako, K. [Mitsubishi Electric Corp. (Japan). Energy and Industrial Systems Center; Hirano, Y.; Yagi, Y.; Shimada, T.; Sekine, S.; Sakakita, H. [Electrotechnical Lab. (Japan)

    1998-07-01

    The construction of TPE-RX reversed field pinch(RFP) machine at the Electrotechnical Laboratory (ETL) was complete at the end of 1997 and the coil system showed the expected performances on the test at the ETL site. In the reversed field pinch machine, the plasma is surrounded by a thick metal shell to maintain plasma equilibrium and to obtain plasma stability. We designed the coil system considering an error magnetic field which is generated by an iron core and the poloidal shell gap of the thick shell. This paper describes designs and the related studies of the equilibrium field control coil system of TPE-RX. (author)

  19. Characteristics of a large reversed field pinch machine, TPE-RX

    Yagi, Y.; Shimada, T.; Hirano, Y.; Sekine, S.; Sakakita, H.; Koguchi, H.; Kiyama, S.; Maejima, Y.; Hirota, I.; Hayase, K.; Sato, Y.; Sugisaki, K.; Oyabu, I.; Hasegawa, M.; Yamane, M.; Sato, F.; Kuno, K.; Minato, T.; Kiryu, A.; Takagi, S.; Sako, K.; Kudough, F.; Urata, K.; Orita, J.; Kaguchi, H.; Sago, H.; Ue, K.

    1998-01-01

    Construction of a new, large reversed field pinch (RFP) machine called TPE-RX was complete at the end of 1997 as a successor of the previous TPE-1RM20 machine at the Electrotechnical Laboratory (ETL). RFP configuration has been successfully obtained in March 1998. The optimization of the operating condition and discharge cleaning of the wall are presently undergoing with the first physics experiments. This paper is the first report of TPE-RX especially on the goals, overall machine characteristics and the present status. Other papers accompanying with this one will present specific topics on the magnetic coil system and the vacuum vessel system. (author)

  20. Design of equilibrium field control coil system of TPE-RX

    Sato, F.; Hasegawa, M.; Yamane, M.; Oyabu, I.; Urata, K.; Kudough, F.; Minato, T.; Kiryu, A.; Takagi, S.; Kuno, K.; Sako, K.

    1998-01-01

    The construction of TPE-RX reversed field pinch(RFP) machine at the Electrotechnical Laboratory (ETL) was complete at the end of 1997 and the coil system showed the expected performances on the test at the ETL site. In the reversed field pinch machine, the plasma is surrounded by a thick metal shell to maintain plasma equilibrium and to obtain plasma stability. We designed the coil system considering an error magnetic field which is generated by an iron core and the poloidal shell gap of the thick shell. This paper describes designs and the related studies of the equilibrium field control coil system of TPE-RX. (author)

  1. Characteristics of a large reversed field pinch machine, TPE-RX

    Yagi, Y.; Shimada, T.; Hirano, Y.; Sekine, S.; Sakakita, H.; Koguchi, H.; Kiyama, S.; Maejima, Y.; Hirota, I.; Hayase, K.; Sato, Y.; Sugisaki, K. [Electrotechnical Lab., Tsukuba-shi, Ibaraki (Japan); Oyabu, I.; Hasegawa, M.; Yamane, M.; Sato, F.; Kuno, K.; Minato, T.; Kiryu, A.; Takagi, S.; Sako, K. [Mitsubishi Electric Corp. (Japan); Kudough, F.; Urata, K.; Orita, J.; Kaguchi, H.; Sago, H.; Ue, K. [Mitsubishi Heavy Industries Ltd. (Japan)

    1998-07-01

    Construction of a new, large reversed field pinch (RFP) machine called TPE-RX was complete at the end of 1997 as a successor of the previous TPE-1RM20 machine at the Electrotechnical Laboratory (ETL). RFP configuration has been successfully obtained in March 1998. The optimization of the operating condition and discharge cleaning of the wall are presently undergoing with the first physics experiments. This paper is the first report of TPE-RX especially on the goals, overall machine characteristics and the present status. Other papers accompanying with this one will present specific topics on the magnetic coil system and the vacuum vessel system. (author)

  2. Smart Mirrors for Photorefractive Control of Light with Tim Bunning, RX - Agile Filters Application

    2016-11-08

    AFRL-AFOSR-UK-TR-2017-0008 Smart Mirrors for photorefractive control of light with Tim Bunning, RX-- Agile filters application Luciano De Sio...DATE (DD-MM-YYYY)      10-02-2017 2. REPORT TYPE Final 3. DATES COVERED (From - To) 01 Feb 2014 to 31 Jan 2016 4. TITLE AND SUBTITLE Smart Mirrors for...photorefractive control of light with Tim Bunning, RX-- Agile filters application 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA9550-14-1-0050 5c.  PROGRAM

  3. On the behaviour of DIS structure function ratio R(x, Q2) at small x

    Kotikov, A.V.

    1993-01-01

    The behaviour of deep inelastic structure functions is studied at small x in the leading and next-to-leading orders of perturbation theory. The scheme-invariant analysis for the longitudinal and transverse structure functions ratio R(x, Q 2 ), is given. It is found that this ratio tends to zero asymptotically when x -> 0. (author). 12 refs.; 1 fig

  4. Development and validation of fuel height models for terrestrial lidar - RxCADRE 2012

    Eric M. Rowell; Carl A. Seielstad; Roger D. Ottmar

    2016-01-01

    Terrestrial laser scanning (TLS) was used to collect spatially continuous measurements of fuelbed characteristics across the plots and burn blocks of the 2012 RxCADRE experiments in Florida. Fuelbeds were scanned obliquely from plot/block edges at a height of 20 m above ground. Pre-fire blocks were scanned from six perspectives and four perspectives for post-...

  5. Rx for Consumer Health Information: The Magic is in the Right Source

    Blue, Ana Rosa; Curry, Jane

    2010-01-01

    Health information is one of the most popular topics requested, in libraries, by the public. These handouts supported the session titled: "Rx for Consumer Health Information: The Magic is in the Right Source" presented at the 2010 BC Library Conference (theme: Seriously Entertaining: Learning through Fun and Games).

  6. RxPATROL: a Web-based tool for combating pharmacy theft.

    Smith, Meredith Y; Graham, J Aaron; Haddox, J David; Steffey, Amy

    2009-01-01

    To report the incidence of pharmacy-related burglaries and robberies and characteristics of pharmacies where such crimes have occurred using recent data from Rx Pattern Analysis Tracking Robberies & Other Losses (RxPATROL), a national Web-based information clearinghouse on pharmacy-related theft of prescription medications and over-the-counter products. Descriptive, nonexperimental study. United States between 2005 and 2006. Not applicable. Not applicable. Number of pharmacy theft reports received; incident type, date, and location; point of entry; and pharmacy security features. Between 2005 and 2006, 202 pharmacy burglary and 299 pharmacy robbery reports from 45 different states were filed with RxPATROL. More than 70% of pharmacies reporting such crimes lacked a security camera. Among those reporting a burglary, 60% lacked dead bolt locks, a solid exterior door, a motion detector device, or a safe or vault for storage of controlled substances. Burglars most often obtained access to the pharmacy via the front door. RxPATROL is a Web-based tool that can assist pharmacies and law enforcement in collaborating more effectively to combat and prevent pharmacy-related crimes.

  7. NA62 Level 0 trigger: TELDES, TX mezzanine, RX mezzanine integration scenario

    Lupi, Matteo

    2015-01-01

    TELDES is a TEL62 daughter-board used in the generation of the Liquid Krypton Calorimeter primitive for the Level 0 Trigger of the NA62 Experiment. TX and RX mezzanines are daughter boards used in the same trigger system to communicate between different levels of the trigger.

  8. Profiling structured product labeling with NDF-RT and RxNorm

    2012-01-01

    Background Structured Product Labeling (SPL) is a document markup standard approved by Health Level Seven (HL7) and adopted by United States Food and Drug Administration (FDA) as a mechanism for exchanging drug product information. The SPL drug labels contain rich information about FDA approved clinical drugs. However, the lack of linkage to standard drug ontologies hinders their meaningful use. NDF-RT (National Drug File Reference Terminology) and NLM RxNorm as standard drug ontology were used to standardize and profile the product labels. Methods In this paper, we present a framework that intends to map SPL drug labels with existing drug ontologies: NDF-RT and RxNorm. We also applied existing categorical annotations from the drug ontologies to classify SPL drug labels into corresponding classes. We established the classification and relevant linkage for SPL drug labels using the following three approaches. First, we retrieved NDF-RT categorical information from the External Pharmacologic Class (EPC) indexing SPLs. Second, we used the RxNorm and NDF-RT mappings to classify and link SPLs with NDF-RT categories. Third, we profiled SPLs using RxNorm term type information. In the implementation process, we employed a Semantic Web technology framework, in which we stored the data sets from NDF-RT and SPLs into a RDF triple store, and executed SPARQL queries to retrieve data from customized SPARQL endpoints. Meanwhile, we imported RxNorm data into MySQL relational database. Results In total, 96.0% SPL drug labels were mapped with NDF-RT categories whereas 97.0% SPL drug labels are linked to RxNorm codes. We found that the majority of SPL drug labels are mapped to chemical ingredient concepts in both drug ontologies whereas a relatively small portion of SPL drug labels are mapped to clinical drug concepts. Conclusions The profiling outcomes produced by this study would provide useful insights on meaningful use of FDA SPL drug labels in clinical applications through

  9. Profiling structured product labeling with NDF-RT and RxNorm

    Zhu Qian

    2012-12-01

    Full Text Available Abstract Background Structured Product Labeling (SPL is a document markup standard approved by Health Level Seven (HL7 and adopted by United States Food and Drug Administration (FDA as a mechanism for exchanging drug product information. The SPL drug labels contain rich information about FDA approved clinical drugs. However, the lack of linkage to standard drug ontologies hinders their meaningful use. NDF-RT (National Drug File Reference Terminology and NLM RxNorm as standard drug ontology were used to standardize and profile the product labels. Methods In this paper, we present a framework that intends to map SPL drug labels with existing drug ontologies: NDF-RT and RxNorm. We also applied existing categorical annotations from the drug ontologies to classify SPL drug labels into corresponding classes. We established the classification and relevant linkage for SPL drug labels using the following three approaches. First, we retrieved NDF-RT categorical information from the External Pharmacologic Class (EPC indexing SPLs. Second, we used the RxNorm and NDF-RT mappings to classify and link SPLs with NDF-RT categories. Third, we profiled SPLs using RxNorm term type information. In the implementation process, we employed a Semantic Web technology framework, in which we stored the data sets from NDF-RT and SPLs into a RDF triple store, and executed SPARQL queries to retrieve data from customized SPARQL endpoints. Meanwhile, we imported RxNorm data into MySQL relational database. Results In total, 96.0% SPL drug labels were mapped with NDF-RT categories whereas 97.0% SPL drug labels are linked to RxNorm codes. We found that the majority of SPL drug labels are mapped to chemical ingredient concepts in both drug ontologies whereas a relatively small portion of SPL drug labels are mapped to clinical drug concepts. Conclusions The profiling outcomes produced by this study would provide useful insights on meaningful use of FDA SPL drug labels in clinical

  10. Profiling structured product labeling with NDF-RT and RxNorm.

    Zhu, Qian; Jiang, Guoqian; Chute, Christopher G

    2012-12-20

    Structured Product Labeling (SPL) is a document markup standard approved by Health Level Seven (HL7) and adopted by United States Food and Drug Administration (FDA) as a mechanism for exchanging drug product information. The SPL drug labels contain rich information about FDA approved clinical drugs. However, the lack of linkage to standard drug ontologies hinders their meaningful use. NDF-RT (National Drug File Reference Terminology) and NLM RxNorm as standard drug ontology were used to standardize and profile the product labels. In this paper, we present a framework that intends to map SPL drug labels with existing drug ontologies: NDF-RT and RxNorm. We also applied existing categorical annotations from the drug ontologies to classify SPL drug labels into corresponding classes. We established the classification and relevant linkage for SPL drug labels using the following three approaches. First, we retrieved NDF-RT categorical information from the External Pharmacologic Class (EPC) indexing SPLs. Second, we used the RxNorm and NDF-RT mappings to classify and link SPLs with NDF-RT categories. Third, we profiled SPLs using RxNorm term type information. In the implementation process, we employed a Semantic Web technology framework, in which we stored the data sets from NDF-RT and SPLs into a RDF triple store, and executed SPARQL queries to retrieve data from customized SPARQL endpoints. Meanwhile, we imported RxNorm data into MySQL relational database. In total, 96.0% SPL drug labels were mapped with NDF-RT categories whereas 97.0% SPL drug labels are linked to RxNorm codes. We found that the majority of SPL drug labels are mapped to chemical ingredient concepts in both drug ontologies whereas a relatively small portion of SPL drug labels are mapped to clinical drug concepts. The profiling outcomes produced by this study would provide useful insights on meaningful use of FDA SPL drug labels in clinical applications through standard drug ontologies such as NDF-RT and

  11. Effects of Herbal vigRX on Premature Ejaculation: A randomized, double-blind study

    Z Ghafuri

    2010-05-01

    Full Text Available Objective :   "nWe conducted a double-blind, placebo-controlled study todetermine the efficacy of an herbal sexual supplement (vigRX on premature ejaculation (PE. Method: "nA randomized double blind study was conducted on a fixed dose of herbal vigRX at Roozbeh Psychiatry Hospital, Tehran University of Medical Sciences. The sample consisted of 85 married patients diagnosed withprimary PE according to Diagnostic and Statistical Manual of Mental Disorders. Each patient underwent diagnostic evaluation by one trained psychiatrist, using Structured Clinical Interview for DSM-IV-TR. Each patient was evaluated by researchers to exclude the organic sexual dysfunctions. The patients were randomly assigned in to two groups: group 1 consisting of 42 patients receiving placebo, and group 2 consisting of 43 patients receiving 540 mg herbal vigRX for a 4-week treatment course. The effects of the drug on the ejaculatory function in each group were assessed by the intravaginal ejaculation latency time (IELT, and the Chinese Index of Premature Ejaculation (CIPE before and at the end of the treatment course. Statistical analysis was performed using SPSS software (15th version.      Results: "nThe mean IELT increased 22.4 and 32.0 seconds in the placebo and the vigRX group respectively after the treatment course. The mean IELT differences between the two groups was not significant. The mean CIPE score increased 2.40 and 4.37 in the placebo and the vigRX group respectively .The mean CIPE score differences between the two groups was not significant.No side effect was reported by the subjects in neither groups during the treatment course. "nConclusion: Although the improvement in IELT and CIPE scores in the herbal vigRX group was more than the placebo group, this difference was not statistically significant. The increasing of IELT and CIPE score in the placebo group may be due to the placebo effects. Further studies with higher vigRX doses, greater sample size

  12. The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor.

    Townsend, Philip D; Dixon, Christopher H; Slootweg, Erik J; Sukarta, Octavina C A; Yang, Ally W H; Hughes, Timothy R; Sharples, Gary J; Pålsson, Lars-Olof; Takken, Frank L W; Goverse, Aska; Cann, Martin J

    2018-03-02

    Plant nucleotide-binding leucine-rich repeat (NLR) proteins enable the immune system to recognize and respond to pathogen attack. An early consequence of immune activation is transcriptional reprogramming, and some NLRs have been shown to act in the nucleus and interact with transcription factors. The Rx1 NLR protein of potato is further able to bind and distort double-stranded DNA. However, Rx1 host targets that support a role for Rx1 in transcriptional reprogramming at DNA are unknown. Here, we report a functional interaction between Rx1 and Nb Glk1, a Golden2-like transcription factor. Rx1 binds to Nb Glk1 in vitro and in planta. Nb Glk1 binds to known Golden2-like consensus DNA sequences. Rx1 reduces the binding affinity of Nb Glk1 for DNA in vitro. Nb Glk1 activates cellular responses to potato virus X, whereas Rx1 associates with Nb Glk1 and prevents its assembly on DNA in planta unless activated by PVX. This study provides new mechanistic insight into how an NLR can coordinate an immune signaling response at DNA following pathogen perceptions. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  13. Extinctions and Distances to Dark Clouds from 2MASS, MegaCam and IPHAS Surveys: LDN 1525 in the Direction of the Aur OB1 Association

    Straižys V.

    2010-12-01

    Full Text Available The possibility of applying photometry from the 2MASS J, H, Ks, MegaCam u, g and IPHAS r, i, Hα surveys for determining the distance to the dark cloud LDN1525 (TGU 1192 in the direction of the Aur OB1 association is investigated using the red clump giants. The main dust cloud, probably related to the emission nebulae Sh 2-232, Sh 2-233, Sh 2-235, the molecular cloud and the association Aur OB2, is found to be located at a distance of 1.3 kpc from the Sun. The nebula Sh 2-231 can be an object of the Perseus arm. The maximum extinction AV found in the cloud is close to 6 mag.

  14. Volumen de la aurícula izquierda indexada por superficie corporal en sujetos normales divididos por sexo y edad

    Héctor A. Deschle

    2010-01-01

    Full Text Available RESUMENIntroducciónEl tamaño de la aurícula izquierda (AI se ha relacionado con la ocurrencia de eventoscardiovasculares en pacientes mayores sin cardiopatía previa.Los valores considerados normales en adultos se suelen tomar de publicaciones extranjerasque presentan valores disímiles y no incluyen la división por edades, por lo que no quedaclaro el impacto que el envejecimiento podría tener sobre el tamaño auricular izquierdo, locual los hace difícilmente aplicables a la población general.ObjetivosEvaluar las modificaciones en el volumen indexado de la aurícula izquierda en sujetos saludablesde nuestro medio divididos por sexo y edad.Material y métodosEntre 2007 y 2008 ingresaron 725 pacientes asintomáticos sin antecedentes de cardiopatía,diabetes, ni enfermedades de relevancia clínica. Sexo masculino: 325. Se dividieron en gruposetarios: a 65 años. El volumen de laaurícula izquierda (AI se calculó de acuerdo con la fórmula: 8/3 π [(A1(A2/(L] (A1 = áreaen 4 cámaras, A2 = área en 2 cámaras, L = longitud más pequeña entre ambas vistas. Lasuperficie corporal se calculó con la fórmula de Mosteller.ResultadosEl volumen indexado de la AI fue significativamente mayor en varones > 64 años (32,89 ±5,93 cm³/m² con respecto a los tres primeros grupos etarios (p < 0,01. No hubo diferenciassignificativas entre los grupos del sexo femenino.ConclusiónEl volumen de la AI es significativamente mayor en varones de más de 64 años.REV ARGENT CARDIOL 2010;78:39-42.

  15. Near-IR High-Resolution Imaging Polarimetry of the SU Aur Disk: Clues for Tidal Tails?

    De Leon, Jerome; Michihiro, Takami; Karr, Jennifer; Hashimoto, Jun; Kudo, Tomoyuki; Sitko, Michael; Mayama, Satoshi; Kusakabe, Nobuyuki; Grady, Carol A.; McElwain, Michael W.

    2015-01-01

    We present new high-resolution (approximately 0.09) H-band imaging observations of the circumstellar disk around the T Tauri star SU Aur. Our observations with Subaru-HiCIAO have revealed the presence of scattered light as close as 0.15 (approximately 20 AU) to the star. Within our image, we identify bright emission associated with a disk with a minimum radius of approximately 90 AU, an inclination of approximately 35 deg from the plane of the sky, and an approximate PA of 15 deg for the major axis. We find a brightness asymmetry between the northern and southern sides of the disk due to a non-axisymmetric disk structure. We also identify a pair of asymmetric tail structures extending east and west from the disk. The western tail extends at least 2. 5 (350 AU) from the star, and is probably associated with a reflection nebula previously observed at optical and near-IR wavelengths. The eastern tail extends at least 1 (140 AU) at the present signal-to-noise. These tails are likely due to an encounter with an unseen brown dwarf, but our results do not exclude the explanation that these tails are outflow cavities or jets.

  16. CONSTRAINING THE MOVEMENT OF THE SPIRAL FEATURES AND THE LOCATIONS OF PLANETARY BODIES WITHIN THE AB AUR SYSTEM

    Lomax, Jamie R.; Wisniewski, John P.; Hashimoto, Jun [Homer L. Dodge Department of Physics, University of Oklahoma, Norman, OK 73071 (United States); Grady, Carol A. [Exoplanets and Stellar Astrophysics Laboratory, Code 667, Goddard Space Flight Center, Greenbelt, MD 20771 (United States); McElwain, Michael W. [NASA Goddard Space Flight Center, Code 6681, Greenbelt, MD 20771 (United States); Kudo, Tomoyuki; Currie, Thayne M; Egner, Sebastian; Guyon, Olivier; Hayano, Yutaka [Subaru Telescope, National Astronomical Observatory of Japan, 650 North A’ohoku Place, Hilo, HI 96720 (United States); Kusakabe, Nobuhiko; Hayashi, Masahiko [National Astronomical Observatory of Japan, 2-21-1, Osawa, Mitaka, Tokyo, 181-8588 (Japan); Okamoto, Yoshiko K. [Institute of Astrophysics and Planetary Sciences, Faculty of Science, Ibaraki University, 2-1-1 Bunkyo, Mito, Ibaraki 310-8512 (Japan); Fukagawa, Misato [Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043 (Japan); Abe, Lyu [Laboratoire Lagrange (UMR 7293), Universite de Nice-Sophia Antipolis, CNRS, Observatoire de la Cote d’Azur, 28 avenue Valrose, F-06108 Nice Cedex 2 (France); Brandner, Wolfgang; Feldt, Markus [Max Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Brandt, Timothy D. [Astrophysics Department, Institute for Advanced Study, Princeton, NJ 08540 (United States); Carson, Joseph C. [Department of Physics and Astronomy, College of Charleston, 58 Coming Street, Charleston, SC 29424 (United States); Goto, Miwa, E-mail: Jamie.R.Lomax@ou.edu, E-mail: wisniewski@ou.edu, E-mail: carol.a.grady@nasa.gov [Universitäts-Sternwarte München, Ludwig-Maximilians-Universität, Scheinerstr. 1, D-81679 München (Germany); and others

    2016-09-01

    We present a new analysis of multi-epoch, H -band, scattered light images of the AB Aur system. We use a Monte Carlo radiative transfer code to simultaneously model the system’s spectral energy distribution (SED) and H -band polarized intensity (PI) imagery. We find that a disk-dominated model, as opposed to one that is envelope-dominated, can plausibly reproduce AB Aur’s SED and near-IR imagery. This is consistent with previous modeling attempts presented in the literature and supports the idea that at least a subset of AB Aur’s spirals originate within the disk. In light of this, we also analyzed the movement of spiral structures in multi-epoch H -band total light and PI imagery of the disk. We detect no significant rotation or change in spatial location of the spiral structures in these data, which span a 5.8-year baseline. If such structures are caused by disk–planet interactions, the lack of observed rotation constrains the location of the orbit of planetary perturbers to be >47 au.

  17. Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo

    Reinhardt, Robert; Centanin, Lázaro; Tavhelidse, Tinatini; Inoue, Daigo; Wittbrodt, Beate; Concordet, Jean-Paul; Martinez-Morales, Juan Ramón; Wittbrodt, Joachim

    2015-01-01

    Transcriptional networks defining stemness in adult neural stem cells (NSCs) are largely unknown. We used the proximal cis-regulatory element (pCRE) of the retina-specific homeobox gene 2 (rx2) to address such a network. Lineage analysis in the fish retina identified rx2 as marker for multipotent NSCs. rx2-positive cells located in the peripheral ciliary marginal zone behave as stem cells for the neuroretina, or the retinal pigmented epithelium. We identified upstream regulators of rx2 interrogating the rx2 pCRE in a trans-regulation screen and focused on four TFs (Sox2, Tlx, Gli3, and Her9) activating or repressing rx2 expression. We demonstrated direct interaction of the rx2 pCRE with the four factors in vitro and in vivo. By conditional mosaic gain- and loss-of-function analyses, we validated the activity of those factors on regulating rx2 transcription and consequently modulating neuroretinal and RPE stem cell features. This becomes obvious by the rx2-mutant phenotypes that together with the data presented above identify rx2 as a transcriptional hub balancing stemness of neuroretinal and RPE stem cells in the adult fish retina. PMID:25908840

  18. Analisis Pengaruh Rx Level Terhadap Kecepatan Download Data Pada Teknologi GPRS di PT XL Axiata Tbk. Purwokerto

    Aldina Peto Bravi

    2011-02-01

    Full Text Available Data transfer speed on GPRS’s technology isaffected by the present of some obstacles between sender’s side and recipient’s side. Those obstacles cause propagation loss that affect the reduction of power level value (rx level. The reduction will affect the data speed. The lower rx level’s value means the lower dataspeed. This researchwas done by doing drive test on BTS North Purwokerto and BTS Tambaksogra to measure the amount of power measured (Pr andthe download data speed on GPRS’s network. The measuredpower level (Pr was normalized to get rx level value. Regression analysis was done to get the relation between the download speed and the rx level value. Theanalysis has resulted in a model: download speed = 4.1 (rx level 0.459 , with R^2 = 0.380. Correlation analysis shows high correlationbetween rx level and download speed (r = 0.608.

  19. Magnetic Hydrogen Atmosphere Models and the Neutron Star RX J1856.5-3754

    Ho, Wynn C.G.; /MIT, MKI /KIPAC, Menlo Park; Kaplan, David L.; /MIT, MKI; Chang, Philip; /UC, Berkeley, Astron. Dept. /UC, Santa Barbara; van Adelsberg, Matthew; /Cornell; Potekhin, Alexander Y.; /Cornell U., Astron. Dept. /Ioffe Phys. Tech. Inst.

    2006-12-08

    RX J1856.5-3754 is one of the brightest nearby isolated neutron stars, and considerable observational resources have been devoted to it. However, current models are unable to satisfactorily explain the data. We show that our latest models of a thin, magnetic, partially ionized hydrogen atmosphere on top of a condensed surface can fit the entire spectrum, from X-rays to optical, of RX J1856.5-3754, within the uncertainties. In our simplest model, the best-fit parameters are an interstellar column density N{sub H} {approx} 1 x 10{sup 20} cm{sup -2} and an emitting area with R{sup {infinity}} {approx} 17 km (assuming a distance to RX J1856.5-3754 of 140 pc), temperature T{sup {infinity}} {approx} 4.3 x 10{sup 5} K, gravitational redshift z{sub g} {approx} 0.22, atmospheric hydrogen column y{sub H} {approx} 1 g cm{sup -2}, and magnetic field B {approx} (3-4) x 10{sup 12} G; the values for the temperature and magnetic field indicate an effective average over the surface. We also calculate a more realistic model, which accounts for magnetic field and temperature variations over the neutron star surface as well as general relativistic effects, to determine pulsations; we find there exist viewing geometries that produce pulsations near the currently observed limits. The origin of the thin atmospheres required to fit the data is an important question, and we briefly discuss mechanisms for producing these atmospheres. Our model thus represents the most self-consistent picture to date for explaining all the observations of RX J1856.5-3754.

  20. A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models in R.

    Wang, W; Hallow, K M; James, D A

    2016-01-01

    This tutorial presents the application of an R package, RxODE, that facilitates quick, efficient simulations of ordinary differential equation models completely within R. Its application is illustrated through simulation of design decision effects on an adaptive dosing regimen. The package provides an efficient, versatile way to specify dosing scenarios and to perform simulation with variability with minimal custom coding. Models can be directly translated to Rshiny applications to facilitate interactive, real-time evaluation/iteration on simulation scenarios.

  1. Reducing beam hardening effects and metal artefacts using Medipix3RX: With applications from biomaterial science

    Rajendran, K.; Walsh, M. F.; de Ruiter, N. J. A.; Chernoglazov, A. I.; Panta, R. K.; Butler, A. P. H.; Butler, P. H.; Bell, S. T.; Anderson, N. G.; Woodfield, T. B. F.; Tredinnick, S. J.; Healy, J. L.; Bateman, C. J.; Aamir, R.; Doesburg, R. M. N.

    2013-01-01

    This paper discusses methods for reducing beam hardening effects using spectral data for biomaterial applications. A small-animal spectral scanner operating in the diagnostic energy range was used. We investigate the use of photon-processing features of the Medipix3RX ASIC in reducing beam hardening and associated artefacts. A fully operational charge summing mode was used during the imaging routine. We present spectral data collected for metal alloy samples, its analysis using algebraic 3D r...

  2. Building a drug ontology based on RxNorm and other sources.

    Hanna, Josh; Joseph, Eric; Brochhausen, Mathias; Hogan, William R

    2013-12-18

    We built the Drug Ontology (DrOn) because we required correct and consistent drug information in a format for use in semantic web applications, and no existing resource met this requirement or could be altered to meet it. One of the obstacles we faced when creating DrOn was the difficulty in reusing drug information from existing sources. The primary external source we have used at this stage in DrOn's development is RxNorm, a standard drug terminology curated by the National Library of Medicine (NLM). To build DrOn, we (1) mined data from historical releases of RxNorm and (2) mapped many RxNorm entities to Chemical Entities of Biological Interest (ChEBI) classes, pulling relevant information from ChEBI while doing so. We built DrOn in a modular fashion to facilitate simpler extension and development of the ontology and to allow reasoning and construction to scale. Classes derived from each source are serialized in separate modules. For example, the classes in DrOn that are programmatically derived from RxNorm are stored in a separate module and subsumed by classes in a manually-curated, realist, upper-level module of DrOn with terms such as 'clinical drug role', 'tablet', 'capsule', etc. DrOn is a modular, extensible ontology of drug products, their ingredients, and their biological activity that avoids many of the fundamental flaws found in other, similar artifacts and meets the requirements of our comparative-effectiveness research use-case.

  3. Aerobic degradation of buprofezin via novel degradation intermediates by Rhodococcus sp. strain RX-3

    Ruixue Li; Chun Dai; Guangli Wang; Shaoxian Wu; Yubao Gong; Yuanyuan Jiang; Zhijia Wang; Naiyue Sun

    2016-01-01

    Buprofezin is a commonly used chemical with satisfactory efficacy against sucking insect pests, but its disposal causes serious environmental problems. In this study, a bacterial strain RX-3 isolated by continuous enrichment from buprofezin-treated soil was tested for biodegradation of buprofezin. The bacteria were most similar to Rhodococcus sp. based on their morphological, physiological and biochemical characteristics, as well as phylogenetic placement inferred from 16S rRNA gene sequence....

  4. Flutter Analysis of RX-420 Balistic Rocket Fin Involving Rigid Body Modes of Rocket Structures

    Novi Andria

    2013-03-01

    Full Text Available Flutter is a phenomenon that has brought a catastrophic failure to the flight vehicle structure. In this experiment, flutter was analyzed for its symmetric and antisymmetric configuration to understand the effect of rocket rigid modes to the fin flutter characteristic. This research was also expected to find out the safety level of RX-420 structure design. The analysis was performed using half rocket model. Fin structure used in this research was a fin which has semispan 600 mm, thickness 12 mm, chord root 700 mm, chord tip 400 mm, made by Al 6061-T651, double spar configuration with skin thickness of 2 mm. Structural dynamics and flutter stability were analyzed using finite element software implemented on MSC. Nastran. The analysis shows that the antisymmetric flutter mode is more critical than symmetric flutter mode. At sea level altitude, antisymmetric flutter occurs at 6.4 Mach, and symmetric flutter occurs at 10.15 Mach. Compared to maximum speed of RX-420 which is 4.5 Mach at altitude 11 km or equivalent to 2.1 Mach at sea level, it can be concluded that the RX-420 structure design is safe, and flutter will not occur during flight.

  5. Comparisons between simulation and measurements taken with the Medipix3RX detector

    McGrath, J.; Marchal, J.; Plackett, R.; Horswell, I.; Omar, D.; Gimenez, E. N.; Tartoni, N.

    2014-05-01

    A simulation toolkit developed for use at Diamond Light Source is presented, accompanied with experimental validation using a silicon pixel-array sensor coupled to a Medipix3RX chip controlled via the Merlin Readout System. The simulation makes use of Geant4, where photons are tracked in order to determine their position of interaction and energy deposition. Further to this, a Finite Element Methods package, Comsol, is used to model the Charge Induction Efficiencies of various sensors. Results are coupled to Geant4 simulations to provide an accurate method for computing the signals generated on each pixel within the sensor and then an algorithm to model the front-end electronics of the device. The validity of the simulation toolkit is tested by investigating charge-sharing effects using a Medipix3RX chip bump-bonded to a silicon pixel-array sensor. The dependence of the imaging parameters, on the energy threshold, is presented from both simulation and experiment for the Medipix3RX chip operated with and without the charge sharing compensation circuitry enabled. This simulation toolkit can be used to calculate image quality parameters for the next generation of detectors, including CdTe, as well as to improve data corrections on existing detectors on synchrotron beamlines.

  6. Comparisons between simulation and measurements taken with the Medipix3RX detector

    McGrath, J; Marchal, J; Plackett, R; Horswell, I; Omar, D; Gimenez, E N; Tartoni, N

    2014-01-01

    A simulation toolkit developed for use at Diamond Light Source is presented, accompanied with experimental validation using a silicon pixel-array sensor coupled to a Medipix3RX chip controlled via the Merlin Readout System. The simulation makes use of Geant4, where photons are tracked in order to determine their position of interaction and energy deposition. Further to this, a Finite Element Methods package, Comsol, is used to model the Charge Induction Efficiencies of various sensors. Results are coupled to Geant4 simulations to provide an accurate method for computing the signals generated on each pixel within the sensor and then an algorithm to model the front-end electronics of the device. The validity of the simulation toolkit is tested by investigating charge-sharing effects using a Medipix3RX chip bump-bonded to a silicon pixel-array sensor. The dependence of the imaging parameters, on the energy threshold, is presented from both simulation and experiment for the Medipix3RX chip operated with and without the charge sharing compensation circuitry enabled. This simulation toolkit can be used to calculate image quality parameters for the next generation of detectors, including CdTe, as well as to improve data corrections on existing detectors on synchrotron beamlines

  7. Compact and portable X-ray imager system using Medipix3RX

    Garcia-Nathan, T. B.; Kachatkou, A.; Jiang, C.; Omar, D.; Marchal, J.; Changani, H.; Tartoni, N.; van Silfhout, R. G.

    2017-10-01

    In this paper the design and implementation of a novel portable X-ray imager system is presented. The design features a direct X-ray detection scheme by making use of a hybrid detector (Medipix3RX). Taking advantages of the capabilities of the Medipix3RX, like a high resolution, zero dead-time, single photon detection and charge-sharing mode, the imager has a better resolution and higher sensitivity compared to using traditional indirect detection schemes. A detailed description of the system is presented, which consists of a vacuum chamber containing the sensor, an electronic board for temperature management, conditioning and readout of the sensor and a data processing unit which also handles network connection and allow communication with clients by acting as a server. A field programmable gate array (FPGA) device is used to implement the readout protocol for the Medipix3RX, apart from the readout the FPGA can perform complex image processing functions such as feature extraction, histogram, profiling and image compression at high speeds. The temperature of the sensor is monitored and controlled through a PID algorithm making use of a Peltier cooler, improving the energy resolution and response stability of the sensor. Without implementing data compression techniques, the system is capable of transferring 680 profiles/s or 240 images/s in a continuous mode. Implementation of equalization procedures and tests on colour mode are presented in this paper. For the experimental measurements the Medipix3RX sensor was used with a Silicon layer. One of the tested applications of the system is as an X-ray beam position monitor (XBPM) device for synchrotron applications. The XBPM allows a non-destructive real time measurement of the beam position, size and intensity. A Kapton foil is placed in the beam path scattering radiation towards a pinhole camera setup that allows the sensor to obtain an image of the beam. By using profiles of the synchrotron X-ray beam, high frequency

  8. P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy.

    Anthony Sinadinos

    2015-10-01

    Full Text Available Duchenne muscular dystrophy (DMD is the most common inherited muscle disease, leading to severe disability and death in young men. Death is caused by the progressive degeneration of striated muscles aggravated by sterile inflammation. The pleiotropic effects of the mutant gene also include cognitive and behavioral impairments and low bone density. Current interventions in DMD are palliative only as no treatment improves the long-term outcome. Therefore, approaches with a translational potential should be investigated, and key abnormalities downstream from the absence of the DMD product, dystrophin, appear to be strong therapeutic targets. We and others have demonstrated that DMD mutations alter ATP signaling and have identified P2RX7 purinoceptor up-regulation as being responsible for the death of muscles in the mdx mouse model of DMD and human DMD lymphoblasts. Moreover, the ATP-P2RX7 axis, being a crucial activator of innate immune responses, can contribute to DMD pathology by stimulating chronic inflammation. We investigated whether ablation of P2RX7 attenuates the DMD model mouse phenotype to assess receptor suitability as a therapeutic target.Using a combination of molecular, histological, and biochemical methods and behavioral analyses in vivo we demonstrate, to our knowledge for the first time, that genetic ablation of P2RX7 in the DMD model mouse produces a widespread functional attenuation of both muscle and non-muscle symptoms. In dystrophic muscles at 4 wk there was an evident recovery in key functional and molecular parameters such as improved muscle structure (minimum Feret diameter, p < 0.001, increased muscle strength in vitro (p < 0.001 and in vivo (p = 0.012, and pro-fibrotic molecular signatures. Serum creatine kinase (CK levels were lower (p = 0.025, and reduced cognitive impairment (p = 0.006 and bone structure alterations (p < 0.001 were also apparent. Reduction of inflammation and fibrosis persisted at 20 mo in leg (p = 0

  9. Application of a rule extraction algorithm family based on the Re-RX algorithm to financial credit risk assessment from a Pareto optimal perspective

    Yoichi Hayashi

    2016-01-01

    Full Text Available Historically, the assessment of credit risk has proved to be both highly important and extremely difficult. Currently, financial institutions rely on the use of computer-generated credit scores for risk assessment. However, automated risk evaluations are currently imperfect, and the loss of vast amounts of capital could be prevented by improving the performance of computerized credit assessments. A number of approaches have been developed for the computation of credit scores over the last several decades, but these methods have been considered too complex without good interpretability and have therefore not been widely adopted. Therefore, in this study, we provide the first comprehensive comparison of results regarding the assessment of credit risk obtained using 10 runs of 10-fold cross validation of the Re-RX algorithm family, including the Re-RX algorithm, the Re-RX algorithm with both discrete and continuous attributes (Continuous Re-RX, the Re-RX algorithm with J48graft, the Re-RX algorithm with a trained neural network (Sampling Re-RX, NeuroLinear, NeuroLinear+GRG, and three unique rule extraction techniques involving support vector machines and Minerva from four real-life, two-class mixed credit-risk datasets. We also discuss the roles of various newly-extended types of the Re-RX algorithm and high performance classifiers from a Pareto optimal perspective. Our findings suggest that Continuous Re-RX, Re-RX with J48graft, and Sampling Re-RX comprise a powerful management tool that allows the creation of advanced, accurate, concise and interpretable decision support systems for credit risk evaluation. In addition, from a Pareto optimal perspective, the Re-RX algorithm family has superior features in relation to the comprehensibility of extracted rules and the potential for credit scoring with Big Data.

  10. Los asentamientos mineros en la minería aurífera de Nueva Granada durante la época colonial

    Orche García, Enrique; Puche Riart, Octavio

    2000-01-01

    El Virreinato de Nueva Granada ocupaba el área que hoy comprende, total o parcialmente, Colombia, Ecuador, Venezuela y Panamá. Desde las primeras incursiones en este vasto territorio, los españoles constataron la enorme riqueza aurífera existente tanto en los aluviales de sus ríos como en los innumerables filones de cuarzo aflorantes en su agreste orografía y, por ello, acometieron la explotación sistemática de los yacimientos de oro en cuanto obtuvieron todo el metal que los indios fueron ca...

  11. Metales en suelos explotados por la pequeña minería aurífera aluvial en Madre de Dios, Perú

    Velásquez Ramírez, Manuel Gabriel

    2017-01-01

    Universidad Nacional Agraria La Molina. Escuela de Posgrado. Maestría en Suelos La región Madre de Dios es considerada la “Capital de la Biodiversidad del Perú”; sin embargo, su riqueza sufre la deforestación, pérdida de suelo y posible contaminación por mercurio a causa de la minería aurífera aluvial. La investigación se realizó en la comunidad de Fortuna en las concesiones de la empresa comunal Sociedad Minera Fortuna Milagritos S.R.L. El objetivo de la investigación fue evaluar el grado...

  12. Metales pesados en plantas provenientes de áreas afectadas por la minería aurífera en la reserva forestal Imataca, Venezuela

    Reyes Gil, Rosa; Bermúdez, Alexis; De Abreu, Orlando; Alvarado, José; Dominguez, José

    2006-01-01

    Metales pesados en plantas provenientes de áreas afectadas por la minería aurífera en la reserva forestal Imataca, Venezuela. Reyes Gil, Rosa; Bermúdez, Alexis; De Abreu, Orlando; Alvarado, José y Dominguez, José Resumen La Reserva Forestal Imataca ha sido explotada artesanalmente para la extracción de oro de aluvión con la utilización de técnicas agresivas para el ambiente, que incluyen la deforestación de grandes áreas boscosas y el uso de mercurio. El objetivo de este traba...

  13. La biolixiviación como pretratamiento de menas auríferas refractarias en matriz de sulfuros

    Iglesias, N.

    1998-02-01

    Full Text Available In this paper the effectiveness of bacterial leaching as a pretreatment of gold ores bearing sulphide minerals is analysed. Three kinds of matrixes are studied: pyrite, arsenopyrite and copper sulphides. It is concluded that bacterial leaching is an effective pretreatment for these refractory gold-bearing ores. In the case of a pyrite matrix a direct contact between the mineral and the microorganisms is necessary. In the case of copper or/and arsenic sulphide matrix, bacterial leaching may be carried out by indirect contact mechanism with effects separation, thus allowing faster kinetics than conventional bioleaching processes. This kinetic improvement reduces operation times and so the capital and operating costs. In a future, this fact may result in the enlargement of the profitable gold ore reserves, incorporating minerals that, at present, are not considered gold ores since there is not a technology, feasible from an economic point of view, for their treatment.

    En este trabajo se analiza la eficacia de la biolixiviación en el pretratamiento de un conjunto de minerales auríferos en los que la refractariedad viene provocada por la presencia de sulfuros metálicos. Se estudian tres tipos de matrices: pirita, arsenopirita y sulfuros de cobre. Se concluye que la biolixiviación es un pretratamiento eficaz para estos tipos de menas refractarias de oro. En el caso de menas en matriz de pirita es necesario el contacto directo entre el sulfuro y los microorganismos. En el caso de menas en matriz de sulfuros de cobre y/o de sulfuros de arsénico, la biolixiviación puede realizarse por un mecanismo de contacto indirecto con separación de efectos, lo que permite alcanzar una cinética mucho más rápida que la de los procesos convencionales de biolixiviación. Esta mejora cinética reduce los tiempos de operación con el consecuente abaratamiento de instalaciones y coste de operación. Este hecho, en un futuro, puede significar la ampliaci

  14. Espectro óculo-aurículo-vertebral em pacientes com defeitos cardíacos congênitos

    Rafael Fabiano Machado Rosa

    2010-10-01

    Full Text Available FUNDAMENTO: Há poucos estudos avaliando a frequência do espectro óculo-aurículo-vertebral (EOAV nos pacientes com defeitos cardíacos congênitos (DCC. OBJETIVO: Verificar a frequência do EOAV em uma amostra de pacientes com malformações cardíacas graves. MÉTODOS: Avaliamos uma coorte prospectiva de pacientes com DCC, admitidos em uma unidade de terapia intensiva (UTI cardiopediátrica no Brasil. O diagnóstico de EOAV foi feito com base em dados clínicos, considerando critérios padrões. Os pacientes que preenchiam esses critérios foram submetidos ao cariótipo de alta resolução com bandamento GTG e hibridização fluorescente in situ para a microdeleção 22q11.2. O teste exato de Fisher (P < 0,05 foi usado para as análises estatísticas. RESULTADOS: Durante o período de avaliação, 330 pacientes foram hospitalizados pela primeira vez na UTI, mas trinta deles não participaram deste estudo. Dos 300 pacientes que constituíram a amostragem final, o EOAV foi verificado em três casos (1%. Todos apresentaram estudos citogenéticos normais. CONCLUSÃO: O EOAV parece ser uma condição frequente em pacientes com DCC. Contudo, não podemos excluir a possibilidade de que a frequência de EOAV encontrada em nosso estudo possa ter sido subestimada devido à baixa taxa de detecção pré-natal de DCC e ao acesso limitado dos pacientes ao tratamento médico apropriado em nosso meio. Estudos prospectivos futuros com critérios clínicos bem definidos e pacientes com defeitos leves e graves serão importantes para avaliar o papel do EOAV na população em geral de indivíduos com malformações cardíacas.

  15. PET attenuation correction for rigid MR Tx/Rx coils from 176Lu background activity

    Lerche, Christoph W.; Kaltsas, Theodoris; Caldeira, Liliana; Scheins, Jürgen; Rota Kops, Elena; Tellmann, Lutz; Pietrzyk, Uwe; Herzog, Hans; Shah, N. Jon

    2018-02-01

    One challenge for PET-MR hybrid imaging is the correction for attenuation of the 511 keV annihilation radiation by the required RF transmit and/or RF receive coils. Although there are strategies for building PET transparent Tx/Rx coils, such optimised coils still cause significant attenuation of the annihilation radiation leading to artefacts and biases in the reconstructed activity concentrations. We present a straightforward method to measure the attenuation of Tx/Rx coils in simultaneous MR-PET imaging based on the natural 176Lu background contained in the scintillator of the PET detector without the requirement of an external CT scanner or PET scanner with transmission source. The method was evaluated on a prototype 3T MR-BrainPET produced by Siemens Healthcare GmbH, both with phantom studies and with true emission images from patient/volunteer examinations. Furthermore, the count rate stability of the PET scanner and the x-ray properties of the Tx/Rx head coil were investigated. Even without energy extrapolation from the two dominant γ energies of 176Lu to 511 keV, the presented method for attenuation correction, based on the measurement of 176Lu background attenuation, shows slightly better performance than the coil attenuation correction currently used. The coil attenuation correction currently used is based on an external transmission scan with rotating 68Ge sources acquired on a Siemens ECAT HR  +  PET scanner. However, the main advantage of the presented approach is its straightforwardness and ready availability without the need for additional accessories.

  16. Isolation and Characterization of a Broad Spectrum Bacteriocin from Bacillus amyloliquefaciens RX7

    Kong Boon Lim

    2016-01-01

    Full Text Available We isolated a Bacillus strain, RX7, with inhibitory activity against Listeria monocytogenes from soil and identified it as Bacillus amyloliquefaciens based on 16S rRNA gene sequencing. The inhibitory activity was stable over a wide range of pH and was fully retained after 30 min at 80°C, after which it decreased gradually at higher temperatures. The activity was sensitive to the proteolytic action of α-chymotrypsin, proteinase-K, and trypsin, indicating its proteinaceous nature. This bacteriocin was active against a broad spectrum of bacteria and the fungus Candida albicans. Direct detection of antimicrobial activity on a sodium dodecyl sulfate-polyacrylamide gel suggested an apparent molecular mass of approximately 5 kDa. Ammonium sulfate precipitation and anion-exchange and gel permeation chromatography integrated with reverse phase-high-performance liquid chromatography were used for bacteriocin purification. Automated N-terminal Edman degradation of the purified RX7 bacteriocin recognized the first 15 amino acids as NH2-X-Ala-Trp-Tyr-Asp-Ile-Arg-Lys-Leu-Gly-Asn-Lys-Gly-Ala, where the letter X in the sequence indicates an unknown or nonstandard amino acid. Based on BLAST similarity search and multiple alignment analysis, the obtained partial sequence showed high homology with the two-peptide lantibiotic haloduracin (HalA1 from Bacillus halodurans, although at least two amino acids differed between the sequences. A time-kill study demonstrated a bactericidal mode of action of RX7 bacteriocin.

  17. Características generales del campo mineral aurífero aguas claras en el contexto geológico regional de la provincia Holguín, Cuba

    Costafreda Mustelier, Jorge Luis

    1996-01-01

    El Campo Mineral Aurífero de Aguas Claras se ubica al norte de Holguín, en una franja alargada de unos 15 kilómetros de longitud. Dentro de este campo mineral se encuentran cuatro minas principales: Nuevo Potosí: Formado por 3 tres cuerpos minerales en forma venas y diseminaciones auríferas (55.783 tn), espesor promedio es de 1,06 metros, contenido medio 7,89 g/t de Au y reserva de metal de 440,0 Kg. Agrupada: La mineralización aparece en venas de hasta 1.0 metro de espe...

  18. Reducing beam hardening effects and metal artefacts using Medipix3RX: With applications from biomaterial science

    Rajendran, K; de Ruiter, N J A; Chernoglazov, A I; Panta, R K; Butler, A P H; Butler, P H; Bell, S T; Anderson, N G; Woodfield, T B F; Tredinnick, S J; Healy, J L; Bateman, C J; Aamir, R; Doesburg, R M N; Renaud, P F; Gieseg, S P; Smithies, D J; Mohr, J L; Mandalika, V B H; Opie, A M T; Cook, N J; Ronaldson, J P; Nik, S J; Atharifard, A; Clyne, M; Bones, P J; Bartneck, C; Grasset, R; Schleich, N; Billinghurst, M

    2014-01-01

    This paper discusses methods for reducing beam hardening effects using spectral data for biomaterial applications. A small-animal spectral scanner operating in the diagnostic energy range was used. We investigate the use of photon-processing features of the Medipix3RX ASIC in reducing beam hardening and associated artefacts. A fully operational charge summing mode was used during the imaging routine. We present spectral data collected for metal alloy samples, its analysis using algebraic 3D reconstruction software and volume visualisation using a custom volume rendering software. Narrow high energy acquisition using the photon-processing detector revealed substantial reduction in beam hardening effects and metal artefacts.

  19. Decoupling of TX and RX antennas in a full-duplex mobile terminal

    Foroozanfard, Ehsan; Carvalho, Elisabeth De; Pedersen, Gert F.

    2016-01-01

    In this paper, a Full-duplex (FD) antenna system is presented with a high isolation between the TX and RX antennas. The isolation method is based on utilizing balanced antennas to localize the current on the ground plane and single mode excitation of the ground plane with capacitive coupling...... elements. The simulation results show a promising isolation level of 75 dB. User impact investigation on the antenna isolation, antenna matching and efficiency is presented. The isolation level varies from 60 dB to 30 dB in the worst user scenarios. The proposed antenna system can be used in a MISO/SIMO FD...

  20. TX-RX isolation method based on polarization diversity, spatial diversity and TX beamforming

    Foroozanfard, Ehsan; Carvalho, Elisabeth De; Pedersen, Gert F.

    2016-01-01

    In this paper, the feasibility of an antenna isolation technique based on null-steer beamforming, polarization diversity and spatial diversity is investigated. The proposed system consists of six patch antennas which are fed by a feeding network to obtain a null-steer beamformer. To achieve spatial...... diversity, antenna elements are located on two layers, facing in a different direction. Moreover, the antenna elements in two layers use different polarization. The measured results of the antenna system present a high TX-RX isolation in the order of 70 dB which shows the feasibility of such a system...

  1. Building a drug ontology based on RxNorm and other sources

    Hanna, Josh; Joseph, Eric; Brochhausen, Mathias; Hogan, William R

    2013-01-01

    Background We built the Drug Ontology (DrOn) because we required correct and consistent drug information in a format for use in semantic web applications, and no existing resource met this requirement or could be altered to meet it. One of the obstacles we faced when creating DrOn was the difficulty in reusing drug information from existing sources. The primary external source we have used at this stage in DrOn’s development is RxNorm, a standard drug terminology curated by the National Libra...

  2. Assessing the economic impact of Rx-to-OTC switches: systematic review and guidelines for future development.

    Cohen, J; Millier, A; Karray, S; Toumi, M

    2013-01-01

    Switching drugs from prescription to non-prescription status (Rx-to-OTC) presents a unique set of challenges and opportunities to policy-makers and the industry in terms of managing health outcomes, pharmaceutical spending, and steering of consumer choices of therapy. Decision-analytic models are used to address uncertainty and produce reasonable estimates of the economic impact of switches for payers. This article presents a critical literature review of existing models which assess the economic impact of Rx-to-OTC switches, and provides guidelines in which future economic evaluations of Rx-to-OTC switches could be improved. A comprehensive search strategy was implemented in Medline and Embase, to retrieve published economic evaluations on Rx-to-OTC switches from 1995-2010. The research digest of the International Society of Pharmacoeconomics and Outcomes Research (ISPOR) was reviewed for potentially relevant abstracts for the past 3 years. Each model used was critically evaluated in terms of structure, relevance of inputs, methodology used, and robustness of results. Worldwide, the economic impact of Rx-to-OTC switches has only been evaluated in a total of 12 peer-reviewed publications. Ten out of 12 studies were US-based, and two European-based. The models covered various disease categories, including allergy, hypercholesterolemia, gastroenterology, contraception, pulmonology, and virology. Seventy-five per cent of the models predicted cost savings for payers and patients. Limitations of the models mainly included use of strong assumptions and non-inclusion of specific populations due to lack of data. Guidelines were developed to help future model development. They cover structural issues on decision context, health states, and clinical outcomes, and other considerations for model specifications. Although reviewed studies lacked quality, this review of economic evidence of Rx-to-OTC switches suggests that switches may produce cost savings to public and private

  3. Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK.

    Torricelli, Andre A M; Santhanam, Abirami; Agrawal, Vandana; Wilson, Steven E

    2014-01-01

    To perform a masked study to determine whether resolvin E1 (RvE1), a lipid-derived immunomodulator, could regulate the development of corneal haze and opacity-related myofibroblasts after opacity-generating high correction photorefractive keratectomy (PRK) in rabbits. Three groups of eight rabbits each were included in the study. Nine diopter (D) PRK for myopia was performed in each test cornea, and the eyes were treated with 30 µl of topical solution every 4 h (six times a day) for 5 days starting immediately after PRK. Group 1 was treated with 0.1% RX-10045, a prodrug of an RvE1 analog; group 2 was treated with 0.01% RX-10045; and group 3 was treated with vehicle control solution. At 1 month after PRK, haze was graded at the slit-lamp by a masked observer. Immunohistochemistry for α-smooth muscle actin (SMA) was performed on the central cornea of each test eye to determine the anterior stromal myofibroblast density. Corneal opacity was significantly lower in the 0.1% RX-10045 group, but not the 0.01% RX-10045 group, compared to the vehicle control group (p=0.029), at 1 month after -9.0D PRK. At 1 month after -9.0D PRK, SMA+ myofibroblast densities in the anterior stroma were not statistically significantly different among the three groups, although a trend toward lower myofibroblast generation was noted in the 0.1% RX-10045 group. Topical 0.1% RX-10045, a prodrug of an RvE1 analog, reduces corneal opacity after haze-generating PRK in rabbits. Further studies are needed to determine the precise points at which RvE1 decreases corneal opacity after injury.

  4. Nucleocytoplasmic distribution is required for activation of resistance by the potato NB-LRR receptor Rx1 and is balanced by its functional domains

    Slootweg, E.J.; Roosien, J.; Spiridon, L.N.; Petrescu, A.J.; Tameling, W.I.L.; Joosten, M.H.A.J.; Pomp, H.; Schaik, van C.C.; Dees, R.H.L.; Borst, J.W.; Smant, G.; Schots, A.; Bakker, J.; Goverse, A.

    2010-01-01

    The Rx1 protein, as many resistance proteins of the nucleotide binding–leucine-rich repeat (NB-LRR) class, is predicted to be cytoplasmic because it lacks discernable nuclear targeting signals. Here, we demonstrate that Rx1, which confers extreme resistance to Potato virus X, is located both in the

  5. Ship Detection in Optical Satellite Image Based on RX Method and PCAnet

    Shao, Xiu; Li, Huali; Lin, Hui; Kang, Xudong; Lu, Ting

    2017-12-01

    In this paper, we present a novel method for ship detection in optical satellite image based on the ReedXiaoli (RX) method and the principal component analysis network (PCAnet). The proposed method consists of the following three steps. First, the spatially adjacent pixels in optical image are arranged into a vector, transforming the optical image into a 3D cube image. By taking this process, the contextual information of the spatially adjacent pixels can be integrated to magnify the discrimination between ship and background. Second, the RX anomaly detection method is adopted to preliminarily extract ship candidates from the produced 3D cube image. Finally, real ships are further confirmed among ship candidates by applying the PCAnet and the support vector machine (SVM). Specifically, the PCAnet is a simple deep learning network which is exploited to perform feature extraction, and the SVM is applied to achieve feature pooling and decision making. Experimental results demonstrate that our approach is effective in discriminating between ships and false alarms, and has a good ship detection performance.

  6. RX-08-HD, a low-viscosity, injection-moldable explosive for filling tortuous paths

    Hoffman, D.M.; Jessop, E.S.; Swansiger, R.W.

    1997-10-01

    Cast cure, extrusion cast, and paste extrudable explosives have not been designed for transferring through long tortuous paths or into fine three dimensional shapes. To allow the crystalline explosive to flow a lubricating fluid is required. The energetic liquid ethane trinitrate (TMETN) was used as the lubricant to maximize the explosive energy. TMETN is a liquid nitrate ester which requires stabilization with conventional free radical stabilizers such as 2- nitrodiphenylamine, methyl-nitroanaline, or ethyl centrylite. Since these injection moldable explosives are expected to cure in place, a polyesterurethane binder based on polymeric isocyanate of hexamethylene diisocyanate and polycaprolactone polyols is dissolved in TMETN. The solubility of the polymer precursors in TMETN also reduces the energetic liquids sensitivity. The latent cure catalyst Dabco T-131 was used to minimize shrinkage associated with thermal expansion, reduce cost associated with oven cures, to give 4-6 hour potlife and overnight cure to handling strength. The product RX-08-HD is a new, low-viscosity, injection moldable explosive that can be extruded into complex, void-free shapes. Combined with appropriate design and other aspects of weaponization, RX-08-HD has produced outstanding results.

  7. A Weighted Spatial-Spectral Kernel RX Algorithm and Efficient Implementation on GPUs

    Chunhui Zhao

    2017-02-01

    Full Text Available The kernel RX (KRX detector proposed by Kwon and Nasrabadi exploits a kernel function to obtain a better detection performance. However, it still has two limits that can be improved. On the one hand, reasonable integration of spatial-spectral information can be used to further improve its detection accuracy. On the other hand, parallel computing can be used to reduce the processing time in available KRX detectors. Accordingly, this paper presents a novel weighted spatial-spectral kernel RX (WSSKRX detector and its parallel implementation on graphics processing units (GPUs. The WSSKRX utilizes the spatial neighborhood resources to reconstruct the testing pixels by introducing a spectral factor and a spatial window, thereby effectively reducing the interference of background noise. Then, the kernel function is redesigned as a mapping trick in a KRX detector to implement the anomaly detection. In addition, a powerful architecture based on the GPU technique is designed to accelerate WSSKRX. To substantiate the performance of the proposed algorithm, both synthetic and real data are conducted for experiments.

  8. RECIPE Rx.

    2016-01-01

    As we started planning this issue on food and nutrition, we kept hearing about the importance of cooking. If physicians are going to be credible when talking to patients about healthy eating, they ought to know something about making a healthy meal, right? They might even want to share a recipe. We know many physicians and medical students like to cook, and we thought it would be fun to find out what they are making. So we asked you to share your favorite healthy recipes with us. The following are a few that we received. We’ll post these and others on our website (mnmed.org). Try them out and share them with your patients and colleagues. Also feel free to send us your favorite. We’ll add it to the collection.

  9. Elevación diafragmática con colapso de la aurícula derecha y síntomas de falla cardíaca: Reporte de un caso

    Juan C. Díaz, MD

    2013-01-01

    Se reporta el caso de una paciente que presentó signos y síntomas compatibles con falla cardíaca derecha y en quien los diferentes estudios demostraron una elevación diafragmática con colapso de la aurícula derecha como causa de su sintomatología.

  10. The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor

    Townsend, Philip D.; Dixon, Christopher H.; Slootweg, Erik J.; Sukarta, Octavina C.A.; Yang, Ally W.H.; Hughes, Timothy R.; Sharples, Gary J.; Palsson, Lars-Olof; Takken, Frank L.W.; Goverse, Aska; Cann, Martin J.

    2018-01-01

    Plant NLR proteins enable the immune system to recognise and respond to pathogen attack. An early consequence of immune activation is transcriptional reprogramming and some NLRs have been shown to act in the nucleus and interact with transcription factors. The Rx1 NLR protein of potato is further

  11. Long-term variability in the X-ray emission of RX J0720.4-3125

    de Vries, C.P.; Vink, J.; Méndez, R.M.; Verbunt, F.

    2004-01-01

    We detect a gradual, long-term change in the shape of the X-ray spectrum of the isolated neutron star RX J0720.4-3125, such that the spectrum of the source can no longer be described as a blackbody spectrum. The change is accompanied by an energy-dependent change in the pulse profile. If the X-ray

  12. A Review of Statistical Techniques for 2x2 and RxC Categorical Data Tables In SPSS

    Cengiz BAL

    2009-11-01

    Full Text Available In this study, a review of statistical techniques for RxC categorical data tables is explained in detail. The emphasis is given to the association of techniques and their corresponding data considerations. Some suggestions to how to handle specific categorical data tables in SPSS and common mistakes in the interpretation of the SPSS outputs are shown.

  13. Rx-CADRE (Prescribed Fire Combustion-Atmospheric Dynamics Research Experiments) collaborative research in the core fire sciences

    D. Jimenez; B. Butler; K. Hiers; R. Ottmar; M. Dickinson; R. Kremens; J. O' Brien; A. Hudak; C. Clements

    2009-01-01

    The Rx-CADRE project was the combination of local and national fire expertise in the field of core fire research. The project brought together approximately 30 fire scientists from six geographic regions and seven diff erent agencies. The project objectives were to demonstrate the capacity for collaborative research by bringing together individuals and teams with a...

  14. Measuring radiant emissions from entire prescribed fires with ground, airborne and satellite sensors - RxCADRE 2012

    Matthew B. Dickinson; Andrew T. Hudak; Thomas Zajkowski; E. Louise Loudermilk; Wilfrid Schroeder; Luke Ellison; Robert L. Kremens; William Holley; Otto Martinez; Alexander Paxton; Benjamin C. Bright; Joseph O' Brien; Ben Hornsby; Charles Ichoku; Jason Faulring; Aaron Gerace; David Peterson; Joseph Mauceri

    2016-01-01

    Characterising radiation from wildland fires is an important focus of fire science because radiation relates directly to the combustion process and can be measured across a wide range of spatial extents and resolutions. As part of a more comprehensive set of measurements collected during the 2012 Prescribed Fire Combustion and Atmospheric Dynamics Research (RxCADRE)...

  15. Research Amplitudo Vibration On Holder Due To The Process Of Lathe Nozzle Rocket RX 450

    Ediwan; Budi Djatmiko, Agus; Dody Arisandi, EfFendy; Purnomo, Heri; Ibadi, Mahfud

    2018-04-01

    The main function of the rocket nozzle is to convert the enthalpy efficiency from combustion gas to kinetic energy and also to make high velocity out of the gas. The rocket nozzle usually consists of a converging and diverging part. With a smaller area on the neck and enlarged at the exit area. The velocity flow through the nozzle enlarges into the speed of sound through the neck and then becomes super sonic in the divergent part. Nozzle making or machining using conventional lathes, first performed is drilling on a massive metal that is bonded to the veneer, then after a sufficient gap is done deep-boring. At the time of the process of lathe in the nozzle RX 450 there is an obstacle that is vibrating tool holder chisel or holder so it is worried about not precision of the process of lathe. This should not happen because it can cause failure in the latter for it needs to be studied and studied further so that the lathe process goes accordingly. The holder material of ST 60 with a modulus of elasticity 200 GPa and a nozzle material of AISI 4340 alloy steel with σyield = 470 MPa, Shear Modulus G = 80 GPa. The purpose of this research is to observe the amplitude of vibration on the holder due to RX- 450 nozzle lathe processing for the purpose of amplitude that occurs in accordance with the desired so that the nozzle structure is no damage process. The result of the research was obtained holder with length (L) 80cm, profile width (B) 5 cm, height of profile (H) 10 cm, turning machine ω = 8.98 rad / sec and natural holder frequency ωn = 89.8 rad / second, Amplitude of vibration of δ = 1.21 mm, while the amplitude of the design X = 1.22 mm From the results of this study it can be said that the holder of a chisel or holder can be used as a tool at the time of RX nozzle retrieval process and is quite safe because it works under the condition ω/ω n Rocket Payload "AKPV Engineering University of Wyoming 2009 )

  16. Gestión ambiental de aguas residuales industriales con mercurio proveniente de la minería aurífera a nivel mundial: Estado del arte

    Garzón-Gutiérrez, Jennyfer Magdalia; Rodríguez-Miranda, Juan Pablo

    2015-01-01

    Introducción: Dada la problemática social y ambiental generada por la minería aurífera artesanal y a pequeña escala (MAAPE), se lleva a cabo en el presente documento la revisión del estado del arte en cuanto a la gestión ambiental de aguas residuales con mercurio (Hg) a nivel mundial. Materiales y métodos: La revisión se realizó a partir de artículos científicos publicados durante los últimos cinco años, encontrando que las intervenciones para abordar los impactos por Hg en la MAAPE, se han e...

  17. Alpha-Actinin-3 (ACTN3 R/X Gene Polymorphism and Physical Performance of Multi-Ethnic Malaysian Population

    Hazwani Ahmad Yusof

    2016-09-01

    Full Text Available A disparity population data set in the current literature with limited reports among Asian samples and the inconsistent findings among different ethnic groups warrant further investigation on the association between alpha-actinin-3 (ACTN3 R/X gene polymorphism and human physical performance in Asian population. This study was designed to examine the association between ACTN3 R/X gene polymorphism and physical performance of multi-ethnic Malaysian population. One hundred eighty well-trained athletes (34 endurance, 41 strength, and 105 intermittent and 180 controls were drawn from four ethnic groups in Malaysia (Malay, Chinese, Indian, and Other Bumiputra. A sample of deoxyribonucleic acid (DNA was retrieved from a buccal swab from each participant and the ACTN3 R/X genotype was identified through polymerase chain reaction and restriction fragment length polymorphism analysis. The strength and endurance performances of the athletes were evaluated with maximal voluntary contraction and Yo-Yo intermittent recovery level 2 tests, respectively. The independent t-test, chi-square, multivariate, and one-way analysis of variance were used for data analysis. ACTN3 R/X alleles (p = 0.672 and genotype (p = 0.355 frequencies did not vary much between the multi-ethnic groups of Malaysian athletes. These small variations did not have any influence on handgrip strength (p = 0.334, leg strength (p = 0.256, and Yo-Yo intermittent recovery level 2 performance (p = 0.425 between these ethnic groups. The RR and XX genotypes were more frequent among strength and intermittent athletes, respectively. Athletes with the RR genotype had greater handgrip than those with the RX genotype (p = 0.031, but not different from athletes with the XX genotype (p = 0.228. Athletes with RR genotype also have a higher leg strength than those with the RX (p = 0.001 and XX genotype (p = 0.010. However, the endurance performance was similar among genotype groups (p = 0.385. The ACTN3 R/X

  18. HOT GAS LINES IN T TAURI STARS

    Ardila, David R.; Herczeg, Gregory J.; Gregory, Scott G.; Hillenbrand, Lynne A.; Ingleby, Laura; Bergin, Edwin; Bethell, Thomas; Calvet, Nuria; France, Kevin; Brown, Alexander; Edwards, Suzan; Johns-Krull, Christopher; Linsky, Jeffrey L.; Yang, Hao; Valenti, Jeff A.; Abgrall, Hervé; Alexander, Richard D.; Brown, Joanna M.; Espaillat, Catherine; Hussain, Gaitee

    2013-01-01

    For Classical T Tauri Stars (CTTSs), the resonance doublets of N V, Si IV, and C IV, as well as the He II 1640 Å line, trace hot gas flows and act as diagnostics of the accretion process. In this paper we assemble a large high-resolution, high-sensitivity data set of these lines in CTTSs and Weak T Tauri Stars (WTTSs). The sample comprises 35 stars: 1 Herbig Ae star, 28 CTTSs, and 6 WTTSs. We find that the C IV, Si IV, and N V lines in CTTSs all have similar shapes. We decompose the C IV and He II lines into broad and narrow Gaussian components (BC and NC). The most common (50%) C IV line morphology in CTTSs is that of a low-velocity NC together with a redshifted BC. For CTTSs, a strong BC is the result of the accretion process. The contribution fraction of the NC to the C IV line flux in CTTSs increases with accretion rate, from ∼20% to up to ∼80%. The velocity centroids of the BCs and NCs are such that V BC ∼> 4 V NC , consistent with the predictions of the accretion shock model, in at most 12 out of 22 CTTSs. We do not find evidence of the post-shock becoming buried in the stellar photosphere due to the pressure of the accretion flow. The He II CTTSs lines are generally symmetric and narrow, with FWHM and redshifts comparable to those of WTTSs. They are less redshifted than the CTTSs C IV lines, by ∼10 km s –1 . The amount of flux in the BC of the He II line is small compared to that of the C IV line, and we show that this is consistent with models of the pre-shock column emission. Overall, the observations are consistent with the presence of multiple accretion columns with different densities or with accretion models that predict a slow-moving, low-density region in the periphery of the accretion column. For HN Tau A and RW Aur A, most of the C IV line is blueshifted suggesting that the C IV emission is produced by shocks within outflow jets. In our sample, the Herbig Ae star DX Cha is the only object for which we find a P-Cygni profile in the C IV

  19. AEEW comments on the NNC/CEGB LOCA code validation report RX 440-A

    Brittain, I.; Bryce, W.M.; O'Mahoney, R.; Richards, C.G.; Gibson, I.H.; Porter, W.H.L.; Fell, J.

    1984-03-01

    Comments are made on the NNC/CEGB report PWR/RX 440-A, Review of Validation for the ECCS Evaluation Model Codes, by K.T. Routledge et al, 1982. This set out to review methods and models used in the LOCA safety case for Sizewell B. These methods are embodied in the Evaluation Model Computer codes SATAN-VI, WREFLOOD, WFLASH, LOCTA-IV and COCO. The main application of these codes is the determination of peak clad temperature and overall containment pressure. The comments represent the views of a group which has been involved for a number of years in the development and application of Best-Estimate methods for LOCA analysis. It is the judgement of this group that, overall, the EM methods can be used to make an acceptable safety case, but there are a number of points of detail still to be resolved. (U.K.)

  20. RX J1856.5-3754: A Strange Star with Solid Quark Surface?

    Zhang, Xiaoling; Xu, Renxin; Zhang, Shuangnan

    2003-01-01

    The featureless spectra of isolated 'neutron stars' may indicate that they are actually bare strange stars but a definitive conclusion on the nature of the compact objects cannot be reached until accurate and theoretically calculated spectra of the bare quark surface are known. However due to the complex nonlinearity of quantum chromodynamics it is almost impossible to present a definitive and accurate calculation of the density-dominated quark-gluon plasma from the first principles. Nevertheless it was suggested that cold quark matter with extremely high baryon density could be in a solid state. Within the realms of this possibility we have fitted the 500ks Chandra LETG/HRC data for the brightest isolated neutron star RX 51856.5-3754 with a phenomenological spectral model and found that electric conductivity of quark matter on the stellar surface is about 1.5 x 10(exp 16)/s.

  1. Upgrade of RMS computers for Y2K problems in RX and related building of HANARO

    Kim, Jung Taek; Kim, J. T.; Ham, C. S.; Kim, C. H.; Lee, Bong Jae; Jae, Yoo Kyung

    2000-08-01

    The Objectives of this Project are as follows : - To resolve the problems of Y2k and operation and maintenance of RMS Computers in RX and related Building of HANARO - To upgrade 486 PC to Pentium II PC - To make Windows NT-Based platform for aspects of user - To make an information structure for radiation using ireless and network devices The Contents of the Project are as follows : - To make Windows NT-Based platform for Radiation Monitoring System - To make Software Platform and Environment for the developing the application program - To design and implement Database Structure - To implement RS232c communication program between local indicators and scanning computers - To implement IEEE 802.3 ethernet communication program between scanning computers and RMTs - To implement user interface for radiation monitoring - To test and inspect Y2k problems

  2. Upgrade of RMS computers for Y2K problems in RX and related building of HANARO

    Kim, Jung Taek; Kim, J. T.; Ham, C. S.; Kim, C. H.; Lee, Bong Jae; Jae, Yoo Kyung

    2000-08-01

    The Objectives of this Project are as follows : - To resolve the problems of Y2k and operation and maintenance of RMS Computers in RX and related Building of HANARO - To upgrade 486 PC to Pentium II PC - To make Windows NT-Based platform for aspects of user - To make an information structure for radiation using ireless and network devices The Contents of the Project are as follows : - To make Windows NT-Based platform for Radiation Monitoring System - To make Software Platform and Environment for the developing the application program - To design and implement Database Structure - To implement RS232c communication program between local indicators and scanning computers - To implement IEEE 802.3 ethernet communication program between scanning computers and RMTs - To implement user interface for radiation monitoring - To test and inspect Y2k problems.

  3. Systematic study of spin crossover and structure in [Co(terpyRX)2](Y)2 systems (terpyRX = 4'-alkoxy-2,2':6',2''-terpyridine, X = 4, 8, 12, Y = BF4(-), ClO4(-), PF6(-), BPh4(-))

    Nielsen, Pia; Nielsen, Hans Toftlund; Bond, Andrew

    2009-01-01

    A family of spin crossover cobalt(II) complexes of the type [Co(terpyRX)(2)](Y)(2) x nH(2)O (X = 4, 8, 12 and Y = BF(4)(-), ClO(4)(-), PF(6)(-), BPh(4)(-)) has been synthesized, whereby the alkyl chain length, RX, and counteranion, Y, have been systematically varied. The structural (single crystal...

  4. Characterization of Al-Cu-Mg-Ag Alloy RX226-T8 Plate

    Lach, Cynthia L.; Domack, Marcia S.

    2003-01-01

    Aluminum-copper-magnesium-silver (Al-Cu-Mg-Ag) alloys that were developed for thermal stability also offer attractive ambient temperature strength-toughness combinations, and therefore, can be considered for a broad range of airframe structural applications. The current study evaluated Al-Cu-Mg-Ag alloy RX226-T8 in plate gages and compared performance with sheet gage alloys of similar composition. Uniaxial tensile properties, plane strain initiation fracture toughness, and plane stress tearing resistance of RX226-T8 were examined at ambient temperature as a function of orientation and thickness location in the plate. Properties were measured near the surface and at the mid-plane of the plate. Tensile strengths were essentially isotropic, with variations in yield and ultimate tensile strengths of less than 2% as a function of orientation and through-thickness location. However, ductility varied by more than 15% with orientation. Fracture toughness was generally higher at the mid-plane and greater for the L-T orientation, although the differences were small near the surface of the plate. Metallurgical analysis indicated that the microstructure was primarily recrystallized with weak texture and was uniform through the plate with the exception of a fine-grained layer near the surface of the plate. Scanning electron microscope analysis revealed Al-Cu-Mg second phase particles which varied in composition and were primarily located on grain boundaries parallel to the rolling direction. Fractography of toughness specimens for both plate locations and orientations revealed that fracture occurred predominantly by transgranular microvoid coalescence. Introduction High-strength, low-density Al-Cu-Mg-Ag alloys were initially developed to replace conventional 2000 (Al-Cu-Mg) and 7000 (Al-Zn-Cu-Mg) series aluminum alloys for aircraft structural applications [1]. During the High Speed Civil Transport (HSCT) program, improvements in thermal stability were demonstrated for candidate

  5. Anomalía del retorno venoso sistémico Drenaje anómalo de la vena cava superior derecha a la aurícula izquierda. Revisión de la literatura y reporte de caso

    Giovanny Ríos, MD

    2012-05-01

    Full Text Available La anomalía total del retorno venoso sistémico tiene gran variedad de presentaciones; sin embargo, la patología de más baja frecuencia es el drenaje de vena cava superior derecha a la aurícula izquierda, hecho de peso para que en el mundo se reporten pocos casos. En la Fundación Clínica Abood Shaio se trató el caso de una paciente de seis años de edad con drenaje venoso total de cava superior derecha a la aurícula izquierda, mediante la técnica de movilización de cava superior y anastomosis cavo-atrial, y se obtuvieron buenos resultados. El caso es mención corresponde al número 21 en la literatura mundial.

  6. Generation of mRx-Cre Transgenic Mouse Line for Efficient Conditional Gene Deletion in Early Retinal Progenitors

    Klímová, Lucie; Láchová, Jitka; Machoň, Ondřej; Sedláček, Radislav; Kozmik, Zbyněk

    2013-01-01

    Roč. 8, č. 5 (2013), e63029 E-ISSN 1932-6203 R&D Projects: GA ČR GAP305/11/2198; GA MŠk(CZ) LK11214; GA MŠk(CZ) LM2011032; GA ČR GAP305/10/2143; GA MŠk ED1.1.00/02.0109 Institutional support: RVO:68378050 Keywords : eye development * lens * retina * transgenic mice Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.534, year: 2013

  7. Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism.

    Al-Khalidi, Rasha; Panicucci, Chiara; Cox, Paul; Chira, Natalia; Róg, Justyna; Young, Christopher N J; McGeehan, Rhiannon E; Ambati, Kameshwari; Ambati, Jayakrishna; Zabłocki, Krzysztof; Gazzerro, Elisabetta; Arkle, Stephen; Bruno, Claudio; Górecki, Dariusz C

    2018-04-11

    Duchenne muscular dystrophy (DMD) is the most common inherited muscle disorder that causes severe disability and death of young men. This disease is characterized by progressive muscle degeneration aggravated by sterile inflammation and is also associated with cognitive impairment and low bone density. Given that no current treatment can improve the long-term outcome, approaches with a strong translational potential are urgently needed. Duchenne muscular dystrophy (DMD) alters P2RX7 signaling in both muscle and inflammatory cells and inhibition of this receptor resulted in a significant attenuation of muscle and non-muscle symptoms in DMD mdx mouse model. As P2RX7 is an attractive target in a range of human diseases, specific antagonists have been developed. Yet, these will require lengthy safety testing in the pediatric population of Duchenne muscular dystrophy (DMD) patients. In contrast, Nucleoside Reverse Transcriptase Inhibitors (NRTIs) can act as P2RX7 antagonists and are drugs with an established safety record, including in children. We demonstrate here that AZT (Zidovudine) inhibits P2RX7 functions acting via the same allosteric site as other antagonists. Moreover, short-term AZT treatment at the peak of disease in DMD mdx mice attenuated the phenotype without any detectable side effects. Recovery was evident in the key parameters such as reduced sarcolemma permeability confirmed by lower serum creatine kinase levels and IgG influx into myofibres, decreased inflammatory cell numbers and inflammation markers in leg and heart muscles of treated mice. Moreover, this short-term therapy had some positive impact on muscle strength in vivo and no detrimental effect on mitochondria, which is the main side-effect of Nucleoside Reverse Transcriptase Inhibitors (NRTIs). Given these results, we postulate that AZT could be quickly re-purposed for the treatment of this highly debilitating and lethal disease. This approach is not constrained by causative DMD mutations and

  8. Effect of a pulsating electric field on ECR heating in the CERA-RX(C) X-ray generator

    Balmashnov, A. A., E-mail: abalmashnov@sci.pfu.edu.ru; Kalashnikov, A. V.; Kalashnikov, V. V.; Stepina, S. P.; Umnov, A. M., E-mail: anumnov@yandex.ru [Peoples’ Friendship University of Russia (Russian Federation)

    2016-03-15

    3D particle-in-cell plasma simulations for the field configurations implemented in the CERA-RX(C) ECR X-ray generator (2.45 GHz) have been conducted. Dependences of the energy spectra of electrons incident on the target electrode on the amplitude and frequency of pulsations of the electric field in a megahertz range are derived. The simulation data are compared with the results of the full-scale experiment.

  9. Niveles de mercurio y percepción del riesgo en una población minera aurífera del Guainía (Orinoquia colombiana

    Alvaro J. ldrovo

    2001-06-01

    Full Text Available La minería aurífera en la región de la Orinoquia colombiana ha tenido un importante crecimiento en los últimos 15 años. Esta actividad se ha convertido en un importante problema de salud pública debido a varios factores como el uso de mercurio durante el proceso de amalgamación del oro, la contaminación del ecosistema y la exposición de la población de la región. El objetivo del presente trabajo fue determinar los niveles de mercurio en cabello y sangre en una población minera del departamento del Guainía y la percepción que tiene dicha población del riesgo de usar este elemento. Para tal fin, se encuestaron 78 residentes de la región, de los cuales se obtuvieron 59 muestras de sangre y 61 de cabello. Los resultados indican un precario ambiente laboral y una falta de conocimiento del riesgo ecológico, lo cual permite la contaminación del ecosistema de la Orinoquia. Los individuos perciben la exposición al mercurio como nociva para la salud, aunque sus conocimientos al respecto son inadecuados. Los valores de mercurio en sangre entre los mineros oscilaron entre 6,9 y 168,0 ug/l (promedio=59,16 y entre los individuos indirectamente expuestos fluctuó entre 17,7 y 100,8 ug/l (promedio=53,5. Las concentraciones de mercurio total en cabello oscilaron entre 3,0 y 89,2 ug/g (promedio=26,93 en el grupo de mineros y entre 2,8 y 48,7 ug/g (promedio=22,86 entre los expuestos indirectamente. No se encontraron diferencias significativas en los niveles de mercurio entre los dos grupos estudiados. Se sugieren medidas preventivas y de control de la situación generada por el uso de mercurio en las labores de mineria aurífera de la región.

  10. Derivation of human differential photoreceptor-like cells from the iris by defined combinations of CRX, RX and NEUROD.

    Yuko Seko

    Full Text Available Examples of direct differentiation by defined transcription factors have been provided for beta-cells, cardiomyocytes and neurons. In the human visual system, there are four kinds of photoreceptors in the retina. Neural retina and iris-pigmented epithelium (IPE share a common developmental origin, leading us to test whether human iris cells could differentiate to retinal neurons. We here define the transcription factor combinations that can determine human photoreceptor cell fate. Expression of rhodopsin, blue opsin and green/red opsin in induced photoreceptor cells were dependent on combinations of transcription factors: A combination of CRX and NEUROD induced rhodopsin and blue opsin, but did not induce green opsin; a combination of CRX and RX induced blue opsin and green/red opsin, but did not induce rhodopsin. Phototransduction-related genes as well as opsin genes were up-regulated in those cells. Functional analysis; i.e. patch clamp recordings, clearly revealed that generated photoreceptor cells, induced by CRX, RX and NEUROD, responded to light. The response was an inward current instead of the typical outward current. These data suggest that photosensitive photoreceptor cells can be generated by combinations of transcription factors. The combination of CRX and RX generate immature photoreceptors: and additional NEUROD promotes maturation. These findings contribute substantially to a major advance toward eventual cell-based therapy for retinal degenerative diseases.

  11. Addressing Social Determinants of Health in a Clinic Setting: The WellRx Pilot in Albuquerque, New Mexico.

    Page-Reeves, Janet; Kaufman, Will; Bleecker, Molly; Norris, Jeffrey; McCalmont, Kate; Ianakieva, Veneta; Ianakieva, Dessislava; Kaufman, Arthur

    2016-01-01

    Although it is known that the social determinants of health have a larger influence on health outcomes than health care, there currently is no structured way for primary care providers to identify and address nonmedical social needs experienced by patients seen in a clinic setting. We developed and piloted WellRx, an 11-question instrument used to screen 3048 patients for social determinants in 3 family medicine clinics over a 90-day period. Results showed that 46% of patients screened positive for at least 1 area of social need, and 63% of those had multiple needs. Most of these needs were previously unknown to the clinicians. Medical assistants and community health workers then offered to connect patients with appropriate services and resources to address the identified needs. The WellRx pilot demonstrated that it is feasible for a clinic to implement such an assessment system, that the assessment can reveal important information, and that having information about patients' social needs improves provider ease of practice. Demonstrated feasibility and favorable outcomes led to institutionalization of the WellRx process at a university teaching hospital and influenced the state department of health to require managed care organizations to have community health workers available to care for Medicaid patients. © Copyright 2016 by the American Board of Family Medicine.

  12. Suzaku observation of TeV SNR RX J1713.7-3946

    Takahashi, Tadayuki; Tanaka, Takaaki; Uchiyama, Yasunobu

    2007-01-01

    We report on results from Suzaku broadband X-ray observations of the Galactic supernova remnant (SNR) RX J1713.7-3946 with an energy coverage of 0.4-40 keV. With a sensitive hard X-ray measurement from the HXD PIN on board Suzaku, we determine the hard X-ray spectrum in the 12-40 keV range to be described by a power law with photon index Γ=3.2±0.2, significantly steeper than the soft X-ray index of Γ=2.4±0.05 measured previously with ASCA and other missions. We find that a simple power law fails to describe the full spectral range of 0.4-40 keV and instead a cutoff power law with hard index Γ=1.96±0.05 and high energy cutoff ε c =9±1 keV provides an excellent fit over the full bandpass. (author)

  13. [Memorandum on the origin of Rx, the signal be employed to the heading in the prescription].

    Ohashi, K

    1995-01-01

    The symbol variously written Rp. Rx. or R. is still employed by physicians to head their prescriptions. In our country, we have learned and believe that the origin of the symbol is an abbreviation of the Latin word for "recipe." In Europe, another suggestion of the origin of the symbol appears to represent the astronomical sign of the planet Jupiter. There is, however, no evidence to support this suggestion. As regards the Jupiter symbol it is probably that printer may have used the sign as the nearest approach he had in type to the abbreviated sign for recipe. It is believed that the confusion between the two symbols is due to a mere typographical coincidence. A careful examination of the various styles of writing the symbol, clearly shows that the sign was originally adopted as an abbreviation of the word "recipe." Recently, it has been suggested that the symbol originates in "the eye of Horus," but, as regards the eye of Horus symbol, much more still remains to be examined. Thus, I will suspend judgement until the facts of the matter become clear, and expect further researches in future.

  14. Hidatidosis cardíaca primaria: quiste hidatídico en aurícula derecha con diseminación pulmonar

    Christian Muñoz-Guijosa

    2009-01-01

    Full Text Available La hidatidosis es una enfermedad parasitaria producida por la larva del cestodo Echinococcus. El quiste hidatídico, la forma más habitual de presentación, es producida por la especie E. granulosus. la afectación cardíaca es muy rara, produciéndose en aproximadamente el 0,5–2% de los casos. El 65% de los casos de hidatidosis cardíaca se localizan en las cavidades izquierdas. Presentamos el caso de un paciente en el que la primera localización de la enfermedad fue la aurícula derecha (Ad, junto con diseminación pulmonar quística. La localización exclusiva en las cavidades cardíacas derechas y en la arteria pulmonar constituye una presentación clínica inusual. se ha revisado la bibliografía, prestando especial interés en la importancia de las técnicas de imagen disponibles en la actualidad para su diagnóstico, así como la necesidad de un tratamiento quirúrgico precoz para evitar sus posibles complicaciones.

  15. Moneda y banca en una economía aurífera. La Región de Antioquia (Colombia, 1850-1890

    María Mercedes Botero Restrepo

    2011-06-01

    Full Text Available Desde mediados del siglo XIX Antioquia experimentó un auge de la minería que la posicionó como principal exportadora de oro al mercado externo. El desarrollo de la producción aurífera generó una mayor demanda, razón por lo cual los grandes comerciantes aumentaron la importación de mercancías extranjeras así como productos de otras partes del país. El avance de los intercambios mercantiles estuvo acompañado de un incremento en la circulación monetaria. Con el apoyo de fuentes primarias, en este trabajo pretendo explorar la forma como operó y se adecuó el sistema monetario en esta economía exportadora de oro.In the 1850s, Antioquia started showing significant commercial development resulting mostly from gold-mining expansion. New mining sites generated new markets and trade networks that joined small localities with cities and foreign markets. Based on the archives of commercial houses of the time, this essay contributes to studies of 19th century monetary issues, describing different forms of money placed into circulation that facilitated the exchange of goods and services in this mining economy.

  16. Bloqueo aurículo-ventricular de primer grado en tirotoxicosis aguda First degree atrio-ventricular block in acute thyrotoxicosis

    Antonio R. Vilches

    2004-02-01

    Full Text Available El cuadro clínico de la tirotoxicosis incluye síntomas cardiovasculares variados. La taquicardia sinusal es el trastorno electrocardiográfico más frecuente y los trastornos de conducción son extremadamente raros como modo de presentación. Comunicamos un caso de bloqueo aurículo-ventricular de primer grado en una paciente con hipertiroidismo recién diagnosticado y que comenzó días antes de la consulta con un cuadro general inespecífico. Su evaluación ulterior demostró que se trataba de una tirotoxicosis aguda autoinmune, y su tratamiento con metimazol corrigió el trastorno totalmente. Se discuten los mecanismos fisiopatológicos involucrados y las implicancias clínicas desde el punto de vista del internista.Thyrotoxicosis may present with a variety of cardiovascular symptoms. Sinus tachycardia is the most frequently encountered electrocardiographic abnormality and conduction disturbances are extremely uncommon. We present a case of first degree atrio-ventricular block in a patient with newly diagnosed hyperthyroidism and discuss the underlying pathophysiological mechanisms and the clinical implications from the internist’s standpoint.

  17. Temporal Trends in Antimicrobial Resistance and Virulence-Associated Traits within the Escherichia coli Sequence Type 131 Clonal Group and Its H30 and H30-Rx Subclones, 1968 to 2012

    Olesen, Bente; Frimodt-Møller, Jakob; Leihof, Rikke Fleron

    2014-01-01

    occurred only after 2000 and 2002, respectively, in association with the H30 and H30-Rx subclones, which were characterized by multidrug resistance (including extended-spectrum-beta-lactamase [ESBL] production: H30-Rx) and absence of biofilm production. Capsular antigen K100 occurred exclusively among H30......-Rx ST131 subclones, rather than representing acquisition of resistance by diverse ST131 strains. Distinctive characteristics of the H30-Rx subclone-including specific virulence genes (iutA, afa and dra, kpsII), the K100 capsule, multidrug resistance, and ESBL production-possibly contributed...

  18. Evaluation of a photon counting Medipix3RX CZT spectral x-ray detector

    Jorgensen, Steven M.; Vercnocke, Andrew J.; Rundle, David S.; Butler, Philip H.; McCollough, Cynthia H.; Ritman, Erik L.

    2016-10-01

    We assessed the performance of a cadmium zinc telluride (CZT)-based Medipix3RX x-ray detector as a candidate for micro-computed tomography (micro-CT) imaging. This technology was developed at CERN for the Large Hadron Collider. It features an array of 128 by 128, 110 micrometer square pixels, each with eight simultaneous threshold counters, five of which utilize real-time charge summing, significantly reducing the charge sharing between contiguous pixels. Pixel response curves were created by imaging a range of x-ray intensities by varying x-ray tube current and by varying the exposure time with fixed x-ray current. Photon energy-related assessments were made by flooding the detector with the tin foil filtered emission of an I-125 radioisotope brachytherapy seed and sweeping the energy threshold of each of the four charge-summed counters of each pixel in 1 keV steps. Long term stability assessments were made by repeating exposures over the course of one hour. The high properly-functioning pixel yield (99%), long term stability (linear regression of whole-chip response over one hour of acquisitions: y = -0.0038x + 2284; standard deviation: 3.7 counts) and energy resolution (2.5 keV FWHM (single pixel), 3.7 keV FWHM across the full image) make this device suitable for spectral micro-CT. The charge summing performance effectively reduced the measurement corruption caused by charge sharing which, when unaccounted for, shifts the photon energy assignment to lower energies, degrading both count and energy accuracy. Effective charge summing greatly improves the potential for calibrated, energy-specific material decomposition and K edge difference imaging approaches.

  19. Toward a normalized clinical drug knowledge base in China-applying the RxNorm model to Chinese clinical drugs.

    Wang, Li; Zhang, Yaoyun; Jiang, Min; Wang, Jingqi; Dong, Jiancheng; Liu, Yun; Tao, Cui; Jiang, Guoqian; Zhou, Yi; Xu, Hua

    2018-04-04

    In recent years, electronic health record systems have been widely implemented in China, making clinical data available electronically. However, little effort has been devoted to making drug information exchangeable among these systems. This study aimed to build a Normalized Chinese Clinical Drug (NCCD) knowledge base, by applying and extending the information model of RxNorm to Chinese clinical drugs. Chinese drugs were collected from 4 major resources-China Food and Drug Administration, China Health Insurance Systems, Hospital Pharmacy Systems, and China Pharmacopoeia-for integration and normalization in NCCD. Chemical drugs were normalized using the information model in RxNorm without much change. Chinese patent drugs (i.e., Chinese herbal extracts), however, were represented using an expanded RxNorm model to incorporate the unique characteristics of these drugs. A hybrid approach combining automated natural language processing technologies and manual review by domain experts was then applied to drug attribute extraction, normalization, and further generation of drug names at different specification levels. Lastly, we reported the statistics of NCCD, as well as the evaluation results using several sets of randomly selected Chinese drugs. The current version of NCCD contains 16 976 chemical drugs and 2663 Chinese patent medicines, resulting in 19 639 clinical drugs, 250 267 unique concepts, and 2 602 760 relations. By manual review of 1700 chemical drugs and 250 Chinese patent drugs randomly selected from NCCD (about 10%), we showed that the hybrid approach could achieve an accuracy of 98.60% for drug name extraction and normalization. Using a collection of 500 chemical drugs and 500 Chinese patent drugs from other resources, we showed that NCCD achieved coverages of 97.0% and 90.0% for chemical drugs and Chinese patent drugs, respectively. Evaluation results demonstrated the potential to improve interoperability across various electronic drug systems

  20. Mechanism of action and efficacy of RX-111, a thieno[2,3-c]pyridine derivative and small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs), in delayed-type hypersensitivity, TNBS-induced colitis and experimental autoimmune encephalomyelitis.

    Harris, Nicholas; Koppel, Juraj; Zsila, Ferenc; Juhas, Stefan; Il'kova, Gabriela; Kogan, Faina Yurgenzon; Lahmy, Orly; Wildbaum, Gizi; Karin, Nathan; Zhuk, Regina; Gregor, Paul

    2016-04-01

    Elucidate the mechanism of action of the small molecule inhibitor of protein binding to glycosaminoglycans, RX-111 and assay its anti-inflammatory activity in animal models of inflammatory disease. The glycosaminoglycan, heparin, was used in the mechanism of action study of RX-111. Human T lymphocytes and umbilical vein endothelial cells were used to assay the in vitro activity of RX-111. Mouse and rat models of disease were used to assay the anti-inflammatory activity of RX-111 in vivo. Circular dichroism and UV/Vis absorption spectroscopy were used to study the binding of RX-111 to the glycosaminoglycan, heparin. T lymphocyte rolling on endothelial cells under shear flow was used to assay RX-111 activity in vitro. Delayed-type hypersensitivity (DTH) and tri-nitrobenzene sulfonic acid (TNBS)-induced colitis in mice and experimental autoimmune encephalomyelitis (EAE) in rats were used to assay anti-inflammatory activity of RX-111 in vivo. RX-111 was shown to bind directly to heparin. It inhibited leukocyte rolling on endothelial cells under shear flow and reduced inflammation in the mouse model of DTH. RX-111 was efficacious in the mouse model of inflammatory bowel disease, TNBS-induced colitis and the rat model of multiple sclerosis, EAE. RX-111 exercises its broad spectrum anti-inflammatory activity by a singular mechanism of action, inhibition of protein binding to the cell surface GAG, heparan sulfate. RX-111 and related thieno[2,3-c]pyridine derivatives are potential therapeutics for the treatment of inflammatory and autoimmune diseases.

  1. Decoupling Scheme for a Cryogenic Rx-Only RF Coil for 13C Imaging at 3T

    Sanchez, Juan Diego; Søvsø Szocska Hansen, Esben; Laustsen, Christoffer

    In this study we evaluate the different active decoupling schemes that can be used to drive an Rx-only coil, in order to determine the optimal design for 13C MRI at 3T. Three different circuit schemes are studied: two known ones (with regular series and parallel tuning respectively), and a novel...... one which we found to be optimal for this case. The circuits have been cooled to 77K to reduce coil noise. Preliminary tests with the preamplifier cooled to 77K for reduction of noise figure, are also reported....

  2. Prospects for Cherenkov telescope array observations of the young supernova Remnant RX J1713.7-3946

    Acero, F.; Aloisio, R.; Amans, J.; Blažek, Jiří; Chudoba, Jiří; Ebr, Jan; Janeček, Petr; Mandát, Dušan; Palatka, Miroslav; Prouza, Michael; Schovánek, Petr; Trávníček, Petr; Vraštil, Michal

    2017-01-01

    Roč. 840, č. 2 (2017), s. 1-14, č. článku 74. ISSN 0004-637X R&D Projects: GA MŠk(CZ) 7AMB14AR005; GA MŠk LE13012; GA ČR(CZ) GA14-17501S; GA MŠk LG14019 Institutional support: RVO:68378271 Keywords : cosmic rays * gamma rays: ISM * ISM: individual objects (RX J1713.7-3946, G347.3-0.5) Subject RIV: BF - Elementary Particles and High Energy Physics OBOR OECD: Particles and field physics Impact factor: 5.533, year: 2016

  3. In vitro translocation experiments with RxLR-reporter fusion proteins of Avr1b from Phytophthora sojae and AVR3a from Phytophthora infestans fail to demonstrate specific autonomous uptake in plant and animal cells.

    Wawra, Stephan; Djamei, Armin; Albert, Isabell; Nürnberger, Thorsten; Kahmann, Regine; van West, Pieter

    2013-05-01

    Plant-pathogenic oomycetes have a large set of secreted effectors that can be translocated into their host cells during infection. One group of these effectors are the RxLR effectors for which it has been shown, in a few cases, that the RxLR motif is important for their translocation. It has been suggested that the RxLR-leader sequences alone are enough to translocate the respective effectors into eukaryotic cells through binding to surface-exposed phosphoinositol-3-phosphate. These conclusions were primary based on translocation experiments conducted with recombinant fusion proteins whereby the RxLR leader of RxLR effectors (i.e., Avr1b from Phytophthora sojae) were fused to the green fluorescent protein reporter-protein. However, we failed to observe specific cellular uptake for a comparable fusion protein where the RxLR leader of the P. infestans AVR3a was fused to monomeric red fluorescent protein. Therefore, we reexamined the ability of the reported P. sojae AVR1b RxLR leader to enter eukaryotic cells. Different relevant experiments were performed in three independent laboratories, using fluorescent reporter fusion constructs of AVR3a and Avr1b proteins in a side-by-side comparative study on plant tissue and human and animal cells. We report that we were unable to obtain conclusive evidence for specific RxLR-mediated translocation.

  4. Habilidades funcionais de autocuidado, mobilidade e função social em crianças com fissura labiopalatina e Espectro Óculo-Aurículo-Vertebral (EOAV)

    Luciana Alves de Souza Carvalho

    2016-01-01

    As anomalias craniofaciais ocasionam comprometimentos estéticos e funcionais com grande impacto na saúde e na integração social da criança, com interferência no desenvolvimento global e social. Das anomalias craniofaciais este estudo abordou as Fissuras Labiopalatinas (FLP) e o Espectro Óculo Aurículo Vertebral (EOAV). As FLP constituem malformações resultantes de falta do fechamento completo dos tecidos que compõe o lábio e o palato. O EOAV, também conhecido como Síndrome de Goldenhar, é um...

  5. Development of a Schottky CdTe Medipix3RX hybrid photon counting detector with spatial and energy resolving capabilities

    Gimenez, E.N., E-mail: Eva.Gimenez@diamond.ac.uk [Diamond Light Source, Harwell Campus, Oxforshire OX11 0DE (United Kingdom); Astromskas, V. [University of Surrey (United Kingdom); Horswell, I.; Omar, D.; Spiers, J.; Tartoni, N. [Diamond Light Source, Harwell Campus, Oxforshire OX11 0DE (United Kingdom)

    2016-07-11

    A multichip CdTe-Medipix3RX detector system was developed in order to bring the advantages of photon-counting detectors to applications in the hard X-ray range of energies. The detector head consisted of 2×2 Medipix3RX ASICs bump-bonded to a 28 mm×28 mm e{sup −} collection Schottky contact CdTe sensor. Schottky CdTe sensors undergo performance degrading polarization which increases with temperature, flux and the longer the HV is applied. Keeping the temperature stable and periodically refreshing the high voltage bias supply was used to minimize the polarization and achieve a stable and reproducible detector response. This leads to good quality images and successful results on the energy resolving capabilities of the system. - Highlights: • A high atomic number (CdTe sensor based) photon-counting detector was developed. • Polarization effects affected the image were minimized by regularly refreshing the bias voltage and stabilizing the temperature. • Good spatial resolution and image quality was achieved following this procedure.

  6. Prospects for Cherenkov Telescope Array Observations of the Young Supernova Remnant RX J1713.7−3946

    Acero, F. [CEA/IRFU/SAp, CEA Saclay, Bat 709, Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Aloisio, R.; Amato, E. [Osservatorio Astrofisico di Arcetri, Largo E. Fermi, 5, I-50125 Firenze (Italy); Amans, J. [LUTH and GEPI, Observatoire de Paris, CNRS, PSL Research University, 5 place Jules Janssen, F-92190, Meudon (France); Antonelli, L. A. [INAF—Osservatorio Astronomico di Roma, Via di Frascati 33, I-00040, Monteporzio Catone (Italy); Aramo, C. [INFN Sezione di Napoli, Via Cintia, ed. G, I-80126 Napoli (Italy); Armstrong, T. [Department of Physics and Centre for Advanced Instrumentation, Durham University, South Road, Durham DH1 3LE (United Kingdom); Arqueros, F.; Barrio, J. A. [Grupo de Altas Energías, Universidad Complutense de Madrid., Av Complutense s/n, E-28040 Madrid (Spain); Asano, K. [Institute for Cosmic Ray Research, University of Tokyo, 5-1-5, Kashi-wanoha, Kashiwa, Chiba 277-8582 (Japan); Ashley, M. [School of Physics, University of New South Wales, Sydney NSW 2052 (Australia); Backes, M. [University of Namibia, Department of Physics, 340 Mandume Ndemufayo Ave., Pioneerspark Windhoek (Namibia); Balazs, C. [School of Physics and Astronomy, Monash University, Melbourne, Victoria 3800 (Australia); Balzer, A. [Astronomical Institute Anton Pannekoek, University of Amsterdam, Science Park 904 1098 XH Amsterdam (Netherlands); Bamba, A. [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Barkov, M. [Riken, Institute of Physical and Chemical Research, 2-1 Hirosawa, Wako, Saitama, 351-0198 (Japan); Benbow, W. [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02180 (United States); Bernlöhr, K., E-mail: sano@a.phys.nagoya-u.ac.jp, E-mail: nakamori@sci.kj.yamagata-u.ac.jp [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, D-69117 Heidelberg (Germany); and others

    2017-05-10

    We perform simulations for future Cherenkov Telescope Array (CTA) observations of RX J1713.7−3946, a young supernova remnant (SNR) and one of the brightest sources ever discovered in very high energy (VHE) gamma rays. Special attention is paid to exploring possible spatial (anti)correlations of gamma rays with emission at other wavelengths, in particular X-rays and CO/H i emission. We present a series of simulated images of RX J1713.7−3946 for CTA based on a set of observationally motivated models for the gamma-ray emission. In these models, VHE gamma rays produced by high-energy electrons are assumed to trace the nonthermal X-ray emission observed by XMM-Newton , whereas those originating from relativistic protons delineate the local gas distributions. The local atomic and molecular gas distributions are deduced by the NANTEN team from CO and H i observations. Our primary goal is to show how one can distinguish the emission mechanism(s) of the gamma rays (i.e., hadronic versus leptonic, or a mixture of the two) through information provided by their spatial distribution, spectra, and time variation. This work is the first attempt to quantitatively evaluate the capabilities of CTA to achieve various proposed scientific goals by observing this important cosmic particle accelerator.

  7. Deep H.E.S.S. observations of the supernova remnant RX J0852.0-4622

    Sushch, Iurii; Paz Arribas, Manuel; Komin, Nukri; Schwanke, Ullrich

    2016-06-01

    The largest TeV source, RX J0852.0-4622 (Vela Jr.), is one of the few supernova remnants (SNRs) with well resolved shell-like morphology at very-high-energy (VHE; E>100 GeV) gamma-rays. Strong non-thermal emission across the electromagnetic spectrum from radio to VHE gamma-rays, young age and proximity of the remnant makes it one of the prime objects for the study of particle acceleration aiming to test the paradigm of SNRs being sources of Galactic cosmic rays. Here we present deep H.E.S.S. observations of RX J0852.0-4622 with roughly doubled exposure comparing to previously published results. Improved statistics together with new analysis techniques result in a firm determination of the cut-off in the gamma-ray spectrum and allow the spatially resolved spectroscopy studies. A smooth connection of the H.E.S.S. spectrum to the spectrum at GeV energies as reported by Fermi/LAT provides an exciting opportunity to recover the present-time parent particle population in both leptonic and hadronic scenarios directly from the gamma-ray data alone. These new observations provide us a deeper insight and better understanding of the physical processes in SNRs.

  8. OBSERVATIONS OF THE YOUNG SUPERNOVA REMNANT RX J1713.7-3946 WITH THE FERMI LARGE AREA TELESCOPE

    Abdo, A. A.; Ackermann, M.; Ajello, M.; Allafort, A.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Baldini, L.; Bellazzini, R.; Bregeon, J.; Ballet, J.; Barbiellini, G.; Baring, M. G.; Bastieri, D.; Bonamente, E.; Bouvier, A.; Brandt, T. J.; Brigida, M.; Bruel, P.

    2011-01-01

    We present observations of the young supernova remnant (SNR) RX J1713.7-3946 with the Fermi Large Area Telescope (LAT). We clearly detect a source positionally coincident with the SNR. The source is extended with a best-fit extension of 0. 0 55 ± 0. 0 04 matching the size of the non-thermal X-ray and TeV gamma-ray emission from the remnant. The positional coincidence and the matching extended emission allow us to identify the LAT source with SNR RX J1713.7-3946. The spectrum of the source can be described by a very hard power law with a photon index of Γ = 1.5 ± 0.1 that coincides in normalization with the steeper H.E.S.S.-detected gamma-ray spectrum at higher energies. The broadband gamma-ray emission is consistent with a leptonic origin as the dominant mechanism for the gamma-ray emission.

  9. The RxLR effector Avh241 from Phytophthora sojae requires plasma membrane localization to induce plant cell death.

    Yu, Xiaoli; Tang, Junli; Wang, Qunqing; Ye, Wenwu; Tao, Kai; Duan, Shuyi; Lu, Chenchen; Yang, Xinyu; Dong, Suomeng; Zheng, Xiaobo; Wang, Yuanchao

    2012-10-01

    • The Phytophthora sojae genome encodes hundreds of RxLR effectors predicted to manipulate various plant defense responses, but the molecular mechanisms involved are largely unknown. Here we have characterized in detail the P. sojae RxLR effector Avh241. • To determine the function and localization of Avh241, we transiently expressed it on different plants. Silencing of Avh241 in P. sojae, we determined its virulence during infection. Through the assay of promoting infection by Phytophthora capsici to Nicotiana benthamiana, we further confirmed this virulence role. • Avh241 induced cell death in several different plants and localized to the plant plasma membrane. An N-terminal motif within Avh241 was important for membrane localization and cell death-inducing activity. Two mitogen-activated protein kinases, NbMEK2 and NbWIPK, were required for the cell death triggered by Avh241 in N. benthamiana. Avh241 was important for the pathogen's full virulence on soybean. Avh241 could also promote infection by P. capsici and the membrane localization motif was not required to promote infection. • This work suggests that Avh241 interacts with the plant immune system via at least two different mechanisms, one recognized by plants dependent on subcellular localization and one promoting infection independent on membrane localization. © 2012 The Authors. New Phytologist © 2012 New Phytologist Trust.

  10. La explotación aurífera en el occidente asturiano: evolución histórica y situación actual

    Feo Parrondo, Francisco

    2002-12-01

    Full Text Available Western Asturias in the Spanish northwest has a long gold mining tradition that dates back to before the Roman conquest and has lasted, through ups and downs, into the present day. Mining is now coming back into its own due to Rio Narcea Gold Mines, whose intense digging brought up nearly three tons of gold in the year 2000, fundamentally in the towns of Belmonte and Salas. In addition to mining panning for gold is being revived as a source of the precious metal and a tourist attraction for the Navelgas area of the town of Tineo.

    [es] El noroeste español, y concretamente el occidente asturiano, cuenta con una amplia tradición en la explotación aurífera que es anterior a la conquista romana y que ha perdurado con altibajos hasta nuestros días. Actualmente, esta explotación está adquiriendo notable importancia por la intensa actividad extractiva llevada a cabo por la empresa Rio Narcea Gold Mines, fundamentalmente en los municipios de Belmonte y Salas, que le permitió obtener casi tres toneladas de oro en el año 2000. A esta actividad minera hay que añadir la recuperación del bateo como fuente para obtener oro y atraer turistas hacia el entorno de Navelgas (Tineo. [fr] Dans la région nord-ouest de l'Espagne, et plus précisément dans la partie occidentale des Asturias, il existe une longue tradition dans le domaine de l'exploitation aurifère, qui remonte à une époque antérieure à la conquête romaine et qui a perduré, avec des hauts et des bas, jusqu'à nos jours. A l'heure actuelle, cette exploitation est en train de devenir de plus en plus importante grâce à l'intense activité extractive exercée par l'entrepise Rio Narcea Gold Mines sur les communes de Belmonte et Salas, essentiellement, activité qui lui a permis d'obtenir près de trois tonnes d'or en l'an 2000. A cette activité minière vient à présent s'ajouter l'exploitation du sable aurifère dans une double optique: obtenir de l'or et attirer les

  11. Determinación de propiedades físicas y parámetros de transporte a colas auríferas de mina El Limón

    J. Ramírez

    2006-01-01

    Full Text Available Los parámetros de transporte de colas mineras y otras propiedades físicas, tales como permeabilidad intrínseca, distribución de tamaño de partículas, porosidad y densidad fueron determinados experimentalmente. Se realizaron experimentos de infiltración en columnas de laboratorio con el fin de determinar; la conductividad hidráulica, las propiedades capilares y estudiar el comportamiento hidrodinámico de las colas auríferas. También se hizo uso de un modelo matemático para simular la infiltración isotérmica unidimensional y ajustar los perfiles experimentales, con el propósito de determinar los parámetros de transporte que describen el proceso de infiltración. Aunque los experimentos se realizaron con diferentes grados de compactación, se obtuvieron parámetros con una coherencia razonable para describir la conductividad hidráulica y las propiedades capilares de las colas por este método. Estos parámetros fueron usados en un modelo simple para simular el lavado con agua del cianuro contenido en las colas auríferas.

  12. Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.

    Yang, Ruili; Yu, Tingting; Kou, Xiaoxing; Gao, Xiang; Chen, Chider; Liu, Dawei; Zhou, Yanheng; Shi, Songtao

    2018-06-01

    Ten-eleven translocation (Tet) family-mediated DNA oxidation represents an epigenetic modification capable of converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), which regulates various biological processes. However, it is unknown whether Tet family affects mesenchymal stem cells (MSCs) or the skeletal system. Here we show that depletion of Tet1 and Tet2 results in impaired self-renewal and differentiation of bone marrow MSCs (BMMSCs) and a significant osteopenia phenotype. Tet1 and Tet2 deficiency reduces demethylation of the P2rX7 promoter and downregulates exosome release, leading to intracellular accumulation of miR-297a-5p, miR-297b-5p, and miR-297c-5p. These miRNAs inhibit Runx2 signaling to impair BMMSC function. We show that overexpression of P2rX7 rescues the impaired BMMSCs and osteoporotic phenotype in Tet1 and Tet2 double knockout mice. These results indicate that Tet1 and Tet2 play a critical role in maintaining BMMSC and bone homeostasis through demethylation of P2rX7 to control exosome and miRNA release. This Tet/P2rX7/Runx2 cascade may serve as a target for the development of novel therapies for osteopenia disorders.

  13. Genetic and physical mapping of homologues of the virus resistance gene Rx1 and the cyst nematode resistance gene Gpa2 in potato.

    Bakker, E; Butterbach, P; Rouppe van der Voort, J; van der Vossen, E; van Vliet, J; Bakker, J; Goverse, A

    2003-05-01

    Nine resistance gene homologues (RGHs) were identified in two diploid potato clones (SH and RH), with a specific primer pair based on conserved motifs in the LRR domain of the potato cyst nematode resistance gene Gpa2 and the potato virus X resistance gene Rx1. A modified AFLP method was used to facilitate the genetic mapping of the RGHs in the four haplotypes under investigation. All nine RGHs appeared to be located in the Gpa2/ Rx1 cluster on chromosome XII. Construction of a physical map using bacterial artificial chromosome (BAC) clones for both the Solanum tuberosum ssp. tuberosum and the S. tuberosum ssp. andigena haplotype of SH showed that the RGHs are located within a stretch of less than 200 kb. Sequence analysis of the RGHs revealed that they are highly similar (93 to 95%) to Gpa2 and Rx1. The sequence identities among all RGHs range from 85 to 100%. Two pairs of RGHs are identical, or nearly so (100 and 99.9%), with each member located in a different genotype. Southern-blot analysis on genomic DNA revealed no evidence for additional homologues outside the Gpa2/ Rx1 cluster on chromosome XII.

  14. A DFT Study of R-X Bond Dissociation Enthalpies of Relevance to the Initiation Process of Atom Transfer Radical Polymerization

    Gillies, Malcolm Bjørn; Matyjaszewski, Krzysztof; Norrby, Per-Ola

    2003-01-01

    DFT calculations at the B3P86/6-31G** level have been carried out to derive the bond dissociation energies (BDE) and free energies for a number of R-X systems (X ) Cl, Br, I, N3, and S2-CNMe2) that have been or can potentially be used as initiators for atom transfer radical polymerization (ATRP...

  15. Emission-line widths and stellar-wind flows in T Tauri stars

    Sa, C.; Lago, M.T.V.T.

    1986-01-01

    Spectra are reported of T Tauri stars taken with the IPCS on the Isaac Newton Telescope at the Observatorio del Roque de los Muchachos at a dispersion of l7 A mm -1 . These were taken in order to determine emission-line widths and hence flow velocities in the winds of these stars following the successful modelling of the wind from RU Lupi using such data. Line widths in RW Aur suggest a similar pattern to the wind flow as in RU Lupi with velocities rising in the inner chromosphere of the star and then entering a 'ballistic' zone. The wind from DFTau is also similar but velocities are generally much lower and the lines sharper. (author)

  16. Start-up assist by magnetized plasma flow injection in TPE-RX reversed-field pinch

    Asai, T. [College of Science and Technology, Nihon University, 1-8 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8308 (Japan)]. E-mail: asai@phys.cst.nihon-u.ac.jp; Nagata, M. [Graduate School of Engineering, University of Hyogo, Himeji (Japan); Koguchi, H. [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba (Japan); Hirano, Y. [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba (Japan); Sakakita, H. [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba (Japan); Yambe, K. [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba (Japan); Kiyama, S. [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba (Japan)

    2006-11-15

    A reversed-field pinch (RFP) start-up assisted by a magnetized plasma flow injection was demonstrated for the first time on a TPE-RX machine. This sequence of experiments aimed to establish a new method of ionization, gas-fill and helicity injection in the start-up phase of an RFP. In this start-up method, magnetized and well-ionized plasma is formed by a magnetized coaxial plasma gun and injected into the torus chamber as an initial pre-ionized plasma for RFP formation. In the initial experiments, attenuated density pump-out and comparatively slow decay of the toroidal flux and plasma current were observed as evidence of its being an effective start-up method.

  17. The one-loop partition function of N=4 super-Yang-Mills theory on RxS3

    Spradlin, Marcus; Volovich, Anastasia

    2005-01-01

    We study weakly coupled SU(N)N=4 super-Yang-Mills theory on RxS 3 at infinite N, which has interesting thermodynamics, including a Hagedorn transition, even at zero Yang-Mills coupling. We calculate the exact one-loop partition function below the Hagedorn temperature. Our calculation employs the representation of the one-loop dilatation operator as a spin chain Hamiltonian acting on neighboring sites and a generalization of Polya's counting of necklaces (gauge-invariant operators) to include necklaces with a 'pendant' (an operator which acts on neighboring beads). We find that the one-loop correction to the Hagedorn temperature is δlnT H =+λ/8π 2

  18. A COHERENT TIMING SOLUTION FOR THE NEARBY, THERMALLY EMITTING ISOLATED NEUTRON STAR RX J0420.0-5022

    Kaplan, D. L.; Van Kerkwijk, M. H.

    2011-01-01

    We present a phase-coherent timing solution for RX J0420.0-5022, the coolest (kT ≅ 45 eV) and fastest-spinning (P = 3.45 s) of the seven so-called isolated neutron stars (INSs). Using 14 observations with the XMM-Newton spacecraft in 2010 and 2011, we were able to measure a spin-down rate ν-dot = (-2.3 ± 0.2) x 10 15 Hz s -1 (P-dot =(2.8±0.3)x10 -14 s s -1 ), from which we infer a dipolar magnetic field of 1.0 x 10 13 G. With reasonable confidence we were able to extend the timing solution back to archival XMM-Newton from 2002 and 2003, giving the same solution but with considerably more precision. This gives RX J0420.0-5022 the lowest dipole magnetic field of the INSs. Our spectroscopy does not confirm the broad absorption feature at 0.3 keV hinted at in earlier observations, although difficulties in background subtraction near that energy make conclusions difficult. With this, all six of the INSs that have confirmed periodicities now have constrained spin-downs from coherent solutions. The evidence that the INSs are qualitatively different from rotation-powered pulsars now appears robust, with the likely conclusion that their characteristic ages are systematically older than their true ages, because their fields have decayed. The field decay probably also causes them to be systematically hotter than pulsars of the same (true) age.

  19. X-Ray and Optical Observations of the Unique Binary System HD 49798/RX J0648.0-4418

    Mereghetti, S.; La Palombara, N.; Tiengo, A.; Pizzolato, F.; Esposito, P.; Woudt, P. A.; Israel, G. L.; Stella, L.

    2011-08-01

    We report the results of XMM-Newton observations of HD 49798/RX J0648.0-4418, the only known X-ray binary consisting of a hot sub-dwarf and a white dwarf. The white dwarf rotates very rapidly (P = 13.2 s) and has a dynamically measured mass of 1.28 ± 0.05 M sun. Its X-ray emission consists of a strongly pulsed, soft component, well fit by a blackbody with kT BB ~ 40 eV, accounting for most of the luminosity, and a fainter hard power-law component (photon index ~1.6). A luminosity of ~1032 erg s-1 is produced by accretion onto the white dwarf of the helium-rich matter from the wind of the companion, which is one of the few hot sub-dwarfs showing evidence of mass loss. A search for optical pulsations at the South African Astronomical Observatory 1.9 m telescope gave negative results. X-rays were also detected during the white dwarf eclipse. This emission, with luminosity 2 × 1030 erg s-1, can be attributed to HD 49798 and represents the first detection of a hot sub-dwarf star in the X-ray band. HD 49798/RX J0648.0-4418 is a post-common-envelope binary which most likely originated from a pair of stars with masses ~8-10 M sun. After the current He-burning phase, HD 49798 will expand and reach the Roche lobe, causing a higher accretion rate onto the white dwarf which can reach the Chandrasekhar limit. Considering the fast spin of the white dwarf, this could lead to the formation of a millisecond pulsar. Alternatively, this system could be a Type Ia supernova progenitor with the appealing characteristic of a short time delay, being the descendent of relatively massive stars.

  20. Effect of Icariin on Tibial Dyschondroplasia Incidence and Tibial Characteristics by Regulating P2RX7 in Chickens

    Hui Zhang

    2018-01-01

    Full Text Available Tibial dyschondroplasia (TD is a disease of rapid growing chickens that occurs in many avian species; it is characterized by nonvascular and nonmineralized growth plates, along with tibia bone deformation and lameness. Icariin is widely used to treat bone diseases in humans, but no report is available regarding the effectiveness of icariin against avian TD. Therefore, this study was designed to determine its effect against TD. For this purpose, a total of 180 broiler chicks were distributed into three groups including control, TD, and icariin group. Control group was given a standard normal diet, while TD and icariin groups received normal standard diet containing 50 mg/kg thiram to induce TD from days 3 to 7 after hatch. After the induction of TD, the chicks of icariin group were fed with standard normal diet by adding 10 mg/kg icariin in water. Then morphological and production parameters analysis of tibial bone indicators, physiological index changes, and gene expression were examined. The results showed that icariin administration not only decreased the mortality but also mitigated the lameness and promoted the angiogenesis, which diminished the TD lesion and significantly increased the expression of P2RX7 (P<0.05 in TD affected thiram induced chicks. In conclusion, present findings suggest that icariin has a significant role in promoting the recovery of chicken growth plates affected by TD via regulating the P2RX7. Our findings reveal a new target for clinical treatment and prevention of TD in broiler chickens.

  1. An 8/15-channel Tx/Rx head neck RF coil combination with region-specific B1 + shimming for whole-brain MRI focused on the cerebellum at 7T.

    Pfaffenrot, Viktor; Brunheim, Sascha; Rietsch, Stefan H G; Koopmans, Peter J; Ernst, Thomas M; Kraff, Oliver; Orzada, Stephan; Quick, Harald H

    2018-02-09

    To design and evaluate an 8/15-channel transmit/receive (Tx/Rx) head-neck RF coil combination with region-specific B1+ shimming for whole-brain MRI with focus on improved functional MRI of the cerebellum at 7 T. An 8-channel transceiver RF head coil was combined with a 7-channel receive-only array. The noise parameters and acceleration capabilities of this 8Tx/15Rx coil setup were compared with a commercially available 1Tx/32Rx RF head coil. Region-specific 8-channel B1+ shimming was applied when using the 8Tx/15Rx RF coil. To evaluate the capability for functional MRI of the cerebellum, temporal SNR and statistical nonparametric maps for finger-tapping experiments with 14 healthy subjects were derived by applying a variable slice thickness gradient-echo echo-planar functional MRI sequence. The 8Tx/15Rx setup had a lower maximum noise correlation between channels, but higher average correlations compared with the 1Tx/32Rx coil. Both RF coils exhibited identical g-factors in the cerebellum with R = 3 acceleration. The enlarged FOV of the 8Tx/15Rx coil in combination with region-specific B1+ shimming increased homogeneity of the transmission field and temporal SNR in caudal cerebellar regions. Temporal SNR losses in cranial parts were reduced, resulting in more highly significant voxels in the caudally activated areas and identical patterns in the cranial cerebellar parts during a finger-tapping task. Compared with the 1Tx/32Rx RF coil, the presented 8Tx/15Rx RF coil combination successfully improves functional MRI of the human cerebellum at 7 T while maintaining whole-brain coverage. A clear temporal SNR gain in caudal cerebellar regions is shown. © 2018 International Society for Magnetic Resonance in Medicine.

  2. Espectro óculo-aurículo-vertebral e malformações cardíacas Oculo-auriculo-vertebral spectrum and cardiac malformations

    Rafael Fabiano Machado Rosa

    2010-01-01

    Full Text Available OBJETIVO: Verificar a frequência e tipos de cardiopatias congênitas em uma amostra de pacientes portadores de espectro óculo-aurículo-vertebral (EOAV, tentando correlacionar a presença desta malformação com suas demais características clínicas e evolução. MÉTODOS: A amostra foi composta por 33 indivíduos, todos atendidos em um mesmo centro, no período de janeiro de 1975 a dezembro de 2007. Vinte e dois deles eram do sexo masculino e 11 do feminino e suas idades variaram de 1 dia a 17 anos. Todos apresentavam avaliação cariotípica normal por bandas GTG. Realizou-se uma coleta de dados referentes à sua história clínica, exame físico e resultado de avaliações complementares. RESULTADOS: Anormalidades cardíacas foram observadas em 13 pacientes (39,4%. Dessas, cinco (38,5% eram do tipo conotruncal, sendo o principal defeito a tetralogia de Fallot (n=2. Malformações não usuais identificadas incluíram o cor triatriatum e a dupla via de entrada de ventrículo esquerdo. Diferenças significativas entre as características clínicas do grupo com e sem cardiopatia foram verificadas somente em relação à idade na primeira avaliação, que foi mais baixa naqueles com malformações cardíacas. Cinco indivíduos foram a óbito, quatro deles portadores desses defeitos. CONCLUSÃO: Malformações cardíacas, em especial dos tipos conotruncal e septal, são frequentes entre pacientes com EOAV. A frequência encontrada em nosso estudo foi estatisticamente similar à da maior parte dos trabalhos descritos na literatura, que oscila de 18% a 58%. As cardiopatias congênitas também representam a principal causa de óbito desses indivíduos. Portanto, uma avaliação cardiológica, especialmente precoce, deveria ser sempre realizada nesses pacientes.OBJECTIVE: To verify the frequency and types of congenital heart defects in a sample of patients with oculo-auriculo-vertebral spectrum (OAVS, in an effort to correlate presence of these

  3. Estudio de la flotabilidad de pirita aurífera proveniente de desechos de procesos venezolanos de cianuración

    di Yorio, C.

    2003-10-01

    Full Text Available Gold recovery from by-products of metallurgical cyaniding processes has been frequently subject of study. This work studies the flotability of auriferous pyrite by means of column flotation, taking into consideration its extremely fine size and the presence of residual cyanide. From preliminary results it was decided to study three variables: pH; Aero promoter 407 concentration; and conditioning time. The pH was varied between 4.5 and 6.0; the reagent dose between 33.3 and 133.3 g/t; and the conditioning time between 1 and 5 min. All the other conditions were kept constant. Sulphur content was analysed for all the concentrates obtained in the flotation tests. It was determined that the pH of the pulp and the ion interference on the adsorption of the collector on the surface of the ore exert a notable influence on both the recovery and the quality of the concentrates. The best results were obtained in conditions of pH 4.5 and 5.0, with 1 and 3 min of conditioning time, respectively; the most effective amount of reagent was 66.6 g per ton of cyaniding solid waste.

    La recuperación de oro a partir de desechos de procesos metalúrgicos de cianuración ha sido objeto de estudio frecuentemente. En el presente trabajo, se estudia la flotabilidad de la pirita aurífera mediante el uso de la flotación en columna, tomando en consideración su granulometría, extremadamente fina, y la presencia de cianuro residual del propio proceso de cianuración. A la vista de los resultados preliminares, se decidió estudiar tres variables: pH, dosis de reactivo (Aero promoter 407 y tiempo de acondicionamiento. El pH se varió entre 4,5 y 6,0; la dosis de reactivo entre 33,3 y 133,3 g/t y el tiempo de acondicionamiento entre 1 y 5 min; todas las demás condiciones se mantuvieron fijas. Se analizó el contenido de azufre para todos los concentrados obtenidos en los ensayos de flotación. Se determinó que el pH de la pulpa y la interferencia iónica sobre la

  4. Oro sin sangre basado en la confianza. Ideas para una nueva economía política de la minería aurífera colombiana

    Adolfo Eslava

    2014-06-01

    Full Text Available Este texto pretende avanzar en la construcción de un enfoque alternativo para mirar la realidad minera colombiana. En contraposición a la estigmatización, aquí se destaca el potencial que existe en los pobladores de territorios mineros. Para ello se toma como punto de partida el estudio de la confianza como factor desencadenante de cambios sociales, luego se describen generalidades de la economía política de la minería aurífera y también se aborda el problema del abastecimiento de oro a los joyeros para proponer soluciones cooperativas con beneficios económicos y sociales para la comunidad minera.

  5. Oro sin sangre basado en la confianza. Ideas para una nueva economía política de la minería aurífera colombiana

    Adolfo Eslava

    2014-01-01

    Full Text Available Este texto pretende avanzar en la cons-trucción de un enfoque alternativo para mirar la realidad minera colombiana. En contrapo-sición a la estigmatización, aquí se destaca el potencial que existe en los pobladores de terri-torios mineros. Para ello se toma como punto de partida el estudio de la confianza como factor desencadenante de cambios sociales, luego se describen generalidades de la econo-mía política de la minería aurífera y también se aborda el problema del abastecimiento de oro a los joyeros para proponer soluciones coo-perativas con beneficios económicos y sociales para la comunidad minera.

  6. Aurélien Bernier, 2008, Le climat otage de la finance ou comment le marché boursicote avec les droits à polluer, Essai, Mille et une nuits, Paris, 164 p.

    Béatrice Quenault

    2009-01-01

    Full Text Available Dans cet essai, au titre provocateur « Le climat otage de la finance ou comment le marché boursicote avec les droits à polluer », l’auteur, Aurélien Bernier, ancien membre d’Attac France et chargé de mission dans le domaine de l’environnement, décrypte le fonctionnement d’un nouveau compartiment de la finance internationale, la « finance carbone » constituée d’un ensemble de marchés où s’échangent les permis d’émission négociables ou les unités de réduction d’émissions, communément appelés « ...

  7. ALMA view of RX J1131-1231: Sub-kpc CO (2-1) mapping of a molecular disk in a lensed star-forming quasar host galaxy

    Paraficz, D.; Rybak, M.; McKean, J. P.; Vegetti, S.; Sluse, D.; Courbin, F.; Stacey, H. R.; Suyu, S. H.; Dessauges-Zavadsky, M.; Fassnacht, C. D.; Koopmans, L. V. E.

    2018-05-01

    We present ALMA 2-mm continuum and CO (2-1) spectral line imaging of the gravitationally lensed z = 0.654 star-forming/quasar composite RX J1131-1231 at 240-400 mas angular resolution. The continuum emission is found to be compact and coincident with the optical emission, whereas the molecular gas forms a complete Einstein ring, which shows strong differential magnification. The de-lensed source structure is determined on 400-parsec-scales resolution using a Bayesian pixelated visibility-fitting lens modelling technique. The reconstructed molecular gas velocity-field is consistent with a large rotating disk with a major-axis FWHM 9.4 kpc at an inclination angle of i = 54° and with a maximum rotational velocity of 280 km s-1. From dynamical model fitting we find an enclosed mass within 5 kpc of M(r conversion factor of α = 5.5 ± 2.0 M⊙ (K km s-1 pc2)-1. This suggests that the star-formation efficiency is dependent on the host galaxy morphology as opposed to the nature of the AGN. The far-infrared continuum spectral energy distribution shows evidence for heated dust, equivalent to an obscured star-formation rate of SFR = 69-25+41 × (7.3/μIR) M⊙ yr-1, which demonstrates the composite star-forming and AGN nature of this system.

  8. Evaluation of Radiology Teachers' Performance and Identification of the "Best Teachers" in a Residency Program: Mixed Methodology and Pilot Study of the MEDUC-RX32 Questionnaire.

    Huete, Álvaro; Julio, Rodrigo; Rojas, Viviana; Herrera, Cristián; Padilla, Oslando; Solís, Nancy; Pizarro, Margarita; Etcheberry, Lorena; Sarfatis, Alberto; Pérez, Gonzalo; Díaz, Luis A; Delfino, Alejandro; Muñoz, Estrella; Rivera, Horacio; Parra, Dimitri A; Bitran, Marcela; Riquelme, Arnoldo

    2016-07-01

    Radiology teachers are well trained in their specialty; however, when working in academic institutions, faculty development and promotion through the education pathway tends to be based on their teaching knowledge and skills. The aim of this study is to assess psychometric properties of the Medicina Universidad Católica-Radiology 32 items (MEDUC-RX32), an instrument designed to evaluate the performance of postgraduate radiology teachers and to identify the best teachers. Mixed methodology was used, including qualitative and quantitative phases. The psychometric properties of the MEDUC-RX32 survey were performed by factor analysis (validity), Cronbach alpha coefficient, and G coefficient (reliability). The residents assessed their teachers and simultaneously voted for the "best teacher," which was used as a gold standard for the receiver operating characteristic curves construction comparing their votes with the global score. A total of 28 residents answered 164 surveys. The global score was 6.23 ± 0.8 (scale from 1 to 7). The factor analysis showed six domains of the resident's perception: (1) tutorial teaching, feedback, and independent learning; (2) communication and teamwork; (3) learning objectives; (4) respectful behavior; (5) radiological report; and (6) teaching and care support. The tutor's strengths were related with respectful behavior and teamwork. The instrument is highly reliable with a Cronbach alpha of 0.937 and a G coefficient of 0.831 (with a minimum of 8 residents). The MEDUC-RX32 instrument has a sensitivity of 91.7% and specificity of 83.3% to identify tutors as best teachers with at least one vote with an area under the receiver operating characteristic curve of 0.931 with a cutoff of 5.94. The MEDC-RX32 instrument is a multidimensional, valid, and highly reliable method to evaluate radiology teachers, identifying teachers with excellence in tutorial teaching in a postgraduate radiology program. Copyright © 2016 The Association of

  9. The Hα line forming region of AB Aurigae spatially resolved at sub-AU with the VEGA/CHARA spectro-interferometer

    Rousselet-Perraut, K.; Benisty, M.; Mourard, D.; Rajabi, S.; Bacciotti, F.; Bério, Ph.; Bonneau, D.; Chesneau, O.; Clausse, J. M.; Delaa, O.; Marcotto, A.; Roussel, A.; Spang, A.; Stee, Ph.; Tallon-Bosc, I.; McAlister, H.; ten Brummelaar, T.; Sturmann, J.; Sturmann, L.; Turner, N.; Farrington, C.; Goldfinger, P. J.

    2010-06-01

    Context. A crucial issue in star formation is to understand the physical mechanism by which mass is accreted onto and ejected by a young star. To derive key constraints on the launching point of the jets and on the geometry of the winds, the visible spectro-polarimeter VEGA installed on the CHARA optical array can be an efficient means of probing the structure and the kinematics of the hot circumstellar gas at sub-AU. Aims: For the first time, we observed the Herbig Ae star AB Aur in the Hα emission line, using the VEGA low spectral resolution (R = 1700) on two baselines of the array. Methods: We computed and calibrated the spectral visibilities of AB Aur between 610 nm and 700 nm in spectral bands of 20.4 nm. To simultaneously reproduce the line profile and the inferred visibility around Hα, we used a 1D radiative transfer code (RAMIDUS/PROFILER) that calculates level populations for hydrogen atoms in a spherical geometry and that produces synthetic spectro-interferometric observables. Results: We clearly resolved AB Aur in the Hα line and in a part of the continuum, even at the smallest baseline of 34 m. The small P-Cygni absorption feature is indicative of an outflow but could not be explained by a spherical stellar wind model. Instead, it favors a magneto-centrifugal X-disk or disk-wind geometry. The fit of the spectral visibilities from 610 to 700 nm could not be accounted for by a wind alone, so another component inducing a visibility modulation around Hα needed to be considered. We thus considered a brightness asymmetry possibly caused by large-scale nebulosity or by the known spiral structures. Conclusions: Thanks to the unique capabilities of VEGA, we managed to simultaneously record for the first time a spectrum at a resolution of 1700 and spectral visibilities in the visible range on a target as faint as mV = 7.1. It was possible to rule out a spherical geometry for the wind of AB Aur and provide realistic solutions to account for the Hα emission

  10. A young contracting white dwarf in the peculiar binary HD 49798/RX J0648.0-4418?

    Popov, S. B.; Mereghetti, S.; Blinnikov, S. I.; Kuranov, A. G.; Yungelson, L. R.

    2018-02-01

    HD 49798/RX J0648.0-4418 is a peculiar X-ray binary with a hot subdwarf (sdO) mass donor. The nature of the accreting compact object is not known, but its spin period P = 13.2 s and \\dot{P} =-2.15 × 10^{-15} s s-1 proves that it can be only either a white dwarf or a neutron star. The spin-up has been very stable for more than 20 yr. We demonstrate that the continuous stable spin-up of the compact companion of HD 49798 can be best explained by contraction of a young white dwarf with an age ˜2 Myr. This allows us to interpret all the basic parameters of the system in the framework of an accreting white dwarf. We present examples of binary evolution, which result in such systems. If correct, this is the first direct evidence for a white dwarf contraction in early evolutionary stages.

  11. EUTEMPE-RX, an EC supported FP7 project for the training and education of medical physics experts in radiology

    Bosmans, H.; Van Peteghem, N.; Bliznakova, K.; Vassileva, J.; Padovani, R.; Christofides, S.; Tsapaki, V.; Caruana, C.J.

    2015-01-01

    The core activity of the medical physics expert (MPE) is to ensure optimal use of ionising radiation in health care. It is essential that these health care professionals are trained to the highest level, defined as European Qualifications Framework for Lifelong Learning (EQF) level 8 by the European Commission's Radiation Protection Report 174 'Guidelines on the MPE'. The main objective of the EUTEMPE-RX project is to provide a model training scheme that allows the medical physicist in diagnostic and interventional radiology (D and IR) to reach this high level. A European network of partners was brought together in this FP7 EC project to ensure sufficient expertise in all aspects of the subject and to create a harmonised course programme. Targeted participants are medical physicists in D and IR in hospitals, engineers and scientists in medical device industries and officers working in regulatory authorities. Twelve course modules will be developed at EQF level 8, with radiation safety and diagnostic effectiveness being prevalent subjects. The modules will combine online with face-to-face teaching using a blended learning approach. (authors)

  12. Radial decoupling of small and large dust grains in the transitional disk RX J1615.3-3255

    Kooistra, Robin; Kamp, Inga; Fukagawa, Misato; Menard, Francois; Momose, Munetake; Tsukagoshi, Takashi; Kudo, Tomoyuki; Kusakabe, Nobuhiko; Hashimoto, Jun; Abe, Lyu; hide

    2017-01-01

    We present H-band (1.6 micron) scattered light observations of the transitional disk RX J1615.3-3255, located in the approx. 1 Myr old Lupus association. From a polarized intensity image, taken with the HiCIAO instrument of the Subaru Telescope, we deduce the position angle and the inclination angle of the disk. The disk is found to extend out to 68 +/- 12 AU in scattered light and no clear structure is observed. Our inner working angle of 24 AU does not allow us to detect a central decrease in intensity similar to that seen at 30 AU in the 880 m continuum observations. We compare the observations with multiple disk models based on the spectral energy distribution (SED) and submm interferometry and find that an inner rim of the outer disk at 30 AU containing small silicate grains produces a polarized intensity signal which is an order of magnitude larger than observed. We show that a model in which the small dust grains extend smoothly into the cavity found for large grains is closer to the actual H-band observations. A comparison of models with different dust size distributions suggests that the dust in the disk might have undergone significant processing compared to the interstellar medium.

  13. Mapping the particle acceleration in the cool core of the galaxy cluster RX J1720.1+2638

    Giacintucci, S.; Markevitch, M.; Brunetti, G.; Venturi, T.; ZuHone, J. A.; Mazzotta, P.; Bourdin, H.

    2014-01-01

    We present new deep, high-resolution radio images of the diffuse minihalo in the cool core of the galaxy cluster RX J1720.1+2638. The images have been obtained with the Giant Metrewave Radio Telescope at 317, 617, and 1280 MHz and with the Very Large Array at 1.5, 4.9, and 8.4 GHz, with angular resolutions ranging from 1'' to 10''. This represents the best radio spectral and imaging data set for any minihalo. Most of the radio flux of the minihalo arises from a bright central component with a maximum radius of ∼80 kpc. A fainter tail of emission extends out from the central component to form a spiral-shaped structure with a length of ∼230 kpc, seen at frequencies 1.5 GHz and below. We find indication of a possible steepening of the total radio spectrum of the minihalo at high frequencies. Furthermore, a spectral index image shows that the spectrum of the diffuse emission steepens with increasing distance along the tail. A striking spatial correlation is observed between the minihalo emission and two cold fronts visible in the Chandra X-ray image of this cool core. These cold fronts confine the minihalo, as also seen in numerical simulations of minihalo formation by sloshing-induced turbulence. All these observations favor the hypothesis that the radio-emitting electrons in cluster cool cores are produced by turbulent re-acceleration.

  14. GAMMA-RAY OBSERVATIONS OF THE SUPERNOVA REMNANT RX J0852.0-4622 WITH THE FERMI LARGE AREA TELESCOPE

    Tanaka, T.; Allafort, A.; Funk, S.; Tajima, H.; Uchiyama, Y.; Ballet, J.; Giordano, F.; Hewitt, J.; Lemoine-Goumard, M.; Tibolla, O.

    2011-01-01

    We report on gamma-ray observations of the supernova remnant (SNR) RX J0852.0-4622 with the Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope. In the Fermi-LAT data, we find a spatially extended source at the location of the SNR. The extension is consistent with the SNR size seen in other wavelengths such as X-rays and TeV gamma rays, leading to the identification of the gamma-ray source with the SNR. The spectrum is well described as a power law with a photon index of Γ = 1.85 ± 0.06 (stat) +0.18 -0.19 (sys), which smoothly connects to the H.E.S.S. spectrum in the TeV energy band. We discuss the gamma-ray emission mechanism based on multiwavelength data. The broadband data can be fit well by a model in which the gamma rays are of hadronic origin. We also consider a scenario with inverse Compton scattering of electrons as the emission mechanism of the gamma rays. Although the leptonic model predicts a harder spectrum in the Fermi-LAT energy range, the model can fit the data considering the statistical and systematic errors.

  15. Measuring Radiant Emissions from Entire Prescribed Fires with Ground, Airborne and Satellite Sensors RxCADRE 2012

    Dickinson, Matthew B.; Hudak, Andrew T.; Zajkowski, Thomas; Loudermilk, E. Louise; Schroeder, Wilfrid; Ellison, Luke; Kremens, Robert L.; Holley, William; Martinez, Otto; Paxton, Alexander; hide

    2015-01-01

    Characterising radiation from wildland fires is an important focus of fire science because radiation relates directly to the combustion process and can be measured across a wide range of spatial extents and resolutions. As part of a more comprehensive set of measurements collected during the 2012 Prescribed Fire Combustion and Atmospheric Dynamics Research (RxCADRE) field campaign, we used ground, airborne and spaceborne sensors to measure fire radiative power (FRP) from whole fires, applying different methods to small (2 ha) and large (.100 ha) burn blocks. For small blocks (n1/46), FRP estimated from an obliquely oriented long-wave infrared (LWIR) camera mounted on a boom lift were compared with FRP derived from combined data from tower-mounted radiometers and remotely piloted aircraft systems (RPAS). For large burn blocks (n1/43), satellite FRP measurements from the Moderate-resolution Imaging Spectroradiometer (MODIS) and Visible Infrared Imaging Radiometer Suite (VIIRS) sensors were compared with near-coincident FRP measurements derived from a LWIR imaging system aboard a piloted aircraft. We describe measurements and consider their strengths and weaknesses. Until quantitative sensors exist for small RPAS, their use in fire research will remain limited. For oblique, airborne and satellite sensors, further FRP measurement development is needed along with greater replication of coincident measurements, which we show to be feasible.

  16. Fracture Surgery of the extremities with the intra-operative use of 3D-RX: A randomized multicenter trial (EF3X-trial

    Marmor Meir

    2011-07-01

    Full Text Available Abstract Background Posttraumatic osteoarthritis can develop after an intra-articular extremity fracture, leading to pain and loss of function. According to international guidelines, anatomical reduction and fixation are the basis for an optimal functional result. In order to achieve this during fracture surgery, an optimal view on the position of the bone fragments and fixation material is a necessity. The currently used 2D-fluoroscopy does not provide sufficient insight, in particular in cases with complex anatomy or subtle injury, and even an 18-26% suboptimal fracture reduction is reported for the ankle and foot. More intra-operative information is therefore needed. Recently the 3D-RX-system was developed, which provides conventional 2D-fluoroscopic images as well as a 3D-reconstruction of bony structures. This modality provides more information, which consequently leads to extra corrections in 18-30% of the fracture operations. However, the effect of the extra corrections on the quality of the anatomical fracture reduction and fixation as well as on patient relevant outcomes has never been investigated. The objective of this study protocol is to investigate the effectiveness of the intra-operative use of the 3D-RX-system as compared to the conventional 2D-fluoroscopy in patients with traumatic intra-articular fractures of the wrist, ankle and calcaneus. The effectiveness will be assessed in two different areas: 1 the quality of fracture reduction and fixation, based on the current golden standard, Computed Tomography. 2 The patient-relevant outcomes like functional outcome range of motion and pain. In addition, the diagnostic accuracy of the 3D-RX-scan will be determined in a clinical setting and a cost-effectiveness as well as a cost-utility analysis will be performed. Methods/design In this protocol for an international multicenter randomized clinical trial, adult patients (age > 17 years with a traumatic intra-articular fracture of the

  17. Atrialización de un caso de síndrome de aurícula paralítica Atrialization in one case of atrial palsy syndrome

    Alejandro Orjuela

    Full Text Available El síndrome de aurícula paralítica es una entidad poco común y generalmente se presenta aislada o asociada a trastornos degenerativos musculares. Se ha propuesto un mecanismo de transmisión familiar por transmisión autosómica dominante. Su presentación es más frecuente en hombres jóvenes y puede manifestarse como evento cerebrovascular, falla cardiaca o fenómenos tromboembólicos. En este artículo se presenta el caso de un hombre joven con historia de síncope recurrente y quien había recibido, tiempo atrás, implante de marcapaso definitivo monocameral. Se descartaron enfermedades inflamatorias cardiacas, distrofias musculares y otras causas secundarias de su trastorno en la formación del impulso sinusal. Una vez la batería de su marcapaso se encontró cerca de su fin de vida y durante el cambio programado del generador, se realizó estudio electrofisiológico de la aurícula y no se encontró mayor actividad. Se implantó electrodo atrial y se realizó seguimiento ecocardiográfico de la función auricular, la cual mostró una discreta mejoría al cabo de seis meses post-implante, para retornar a los valores basales, razón por la que se apagó el canal atrial. Aunque algunos pacientes recuperan la función atrial posterior a la cardioversión por fibrilacion atrial, no se conoce el porcentaje de pacientes que lo hacen tras la estimulación atrial en una aurícula poco activa mecánica y eléctricamente. Esto hace útil la medición de la actividad atrial y la estimulación, antes de decidir sobre el implante de un electrodo en el atrio.Atrial palsy syndrome is an uncommon entity which generally occurs isolated or associated with degenerative muscular disorders. An autosomic dominant familiar transmission mechanism has been proposed. It appears more frequently in young males, and may be manifested as cerebro-vascular event, heart failure or thromboembolic phenomena. In this article, the case of a young man with history of

  18. Star Forming Dense Cloud Cores in the TeV -ray SNR RX J1713.7-3946

    Sano, H.; Sato, J.; Yamamoto, H.; Hayakawa, T.; Torii, K.; Moribe, N.; Kawamura, A.; Okuda, T.; Mizuno, N.; Onishi, T.; Maezawa, H.; Inoue, T.; Inutsuka, S.; Tanaka, T.; Mizuno, A.; Ogawa, H.; Stutzki, J.; Bertoldi, F.; Anderl, S.; Bronfman, L.; Koo, B.C.

    2010-10-27

    RX J1713.7-3946 is one of the TeV {gamma}-ray supernova remnants (SNRs) emitting synchrotron X rays. The SNR is associated with molecular gas located at {approx}1 kpc. We made new molecular observations toward the dense cloud cores, peaks A, C and D, in the SNR in the {sup 12}CO(J=2-1) and {sup 13}CO(J=2-1) transitions at angular resolution of 90 degrees. The most intense core in {sup 13}CO, peak C, was also mapped in the {sup 12}CO(J=4-3) transition at angular resolution of 38 degrees. Peak C shows strong signs of active star formation including bipolar outflow and a far-infrared protostellar source and has a steep gradient with a r{sup -2.2 {+-} 0.4} variation in the average density within radius r. Peak C and the other dense cloud cores are rim-brightened in synchrotron X rays, suggesting that the dense cloud cores are embedded within or on the outer boundary of the SNR shell. This confirms the earlier suggestion that the X rays are physically associated with the molecular gas (Fukui et al. 2003). We present a scenario where the densest molecular core, peak C, survived against the blast wave and is now embedded within the SNR. Numerical simulations of the shock-cloud interaction indicate that a dense clump can indeed survive shock erosion, since shock propagation speed is stalled in the dense clump. Additionally, the shock-cloud interaction induces turbulence and magnetic field amplification around the dense clump that may facilitate particle acceleration in the lower-density inter-clump space leading to the enhanced synchrotron X rays around dense cores.

  19. Investigation into the association between P2RX7 gene polymorphisms and susceptibility to primary gout and hyperuricemia in a Chinese Han male population.

    Ying, Ying; Chen, Yong; Li, Zhen; Huang, Haiyan; Gong, Qiongyao

    2017-04-01

    The purpose of this study was to investigate the relationship between P2RX7 gene single nucleotide polymorphisms and primary gout and hyperuricemia in a Chinese Han male population. The genetic distributions of the single nucleotide polymorphisms (SNPs) rs2230911, rs208294, rs435309, rs28360447, rs1718119, rs28360457, and rs3751143 in P2RX7 were detected in 293 primary gout patients, 187 hyperuricemia patients and 269 controls using SNaPshot technology. Statistical analyses were implemented using SPSS version 20.0. The genetic distributions of each group were tested for Hardy-Weinberg equilibrium (HWE). T test, analysis of variance, rank sum test and Chi-square test were measured to assess differences in clinical data and polymorphisms among groups. Logistic regression was used to assess susceptibility to disease with odds ratios (ORs) and 95% confidence intervals (95% CIs). SHEsis software was used to calculate linkage disequilibrium blocks and haplotype association risk. P  .05). In the comparison between primary gout and control, the frequencies of rs2230911 genotypes were significantly different (P = .002), and allele G was associated with a higher risk of primary gout than allele C [OR (95% CI) = 1.755 (1.278, 2.410), P gout in genotype (CG + GG) compared with genotype CC [OR (95% CI) = 1.876 (1.303, 2.701), P = .001]. However, no significant difference in allelic or genotypic frequency was observed between primary gout patients and hyperuricemia patients (P > .0167). Similarly, there were no obvious differences in the other two polymorphisms among the three groups (P > .05). Our results reveal that P2RX7 rs2230911 may be associated with primary gout risk in a Chinese Han male population and allele G may be a susceptibility factor for primary gout.

  20. Community pharmacist participation in a practice-based research network: a report from the Medication Safety Research Network of Indiana (Rx-SafeNet).

    Patel, Puja; Hemmeger, Heather; Kozak, Mary Ann; Gernant, Stephanie A; Snyder, Margie E

    2015-01-01

    To describe the experiences and opinions of pharmacists serving as site coordinators for the Medication Safety Research Network of Indiana (Rx-SafeNet). Retail chain, independent, and hospital/health system outpatient community pharmacies throughout Indiana, with a total of 127 pharmacy members represented by 26 site coordinators. Rx-SafeNet, a statewide practice-based research network (PBRN) formed in 2010 and administered by the Purdue University College of Pharmacy. Barriers and facilitators to participation in available research studies, confidence participating in research, and satisfaction with overall network communication. 22 of 26 site coordinators participated, resulting in an 85% response rate. Most (72.2%) of the respondents had received a doctor of pharmacy degree, and 13.6% had postgraduate year (PGY)1 residency training. The highest reported benefits of PBRN membership were an enhanced relationship with the Purdue University College of Pharmacy (81% agreed or strongly agreed) and enhanced professional development (80% agreed or strongly agreed). Time constraints were identified as the greatest potential barrier to network participation, reported by 62% of respondents. In addition, the majority (59%) of survey respondents identified no prior research experience. Last, respondents' confidence in performing research appeared to increase substantially after becoming network members, with 43% reporting a lack of confidence in engaging in research before joining the network compared with 90% reporting confidence after joining the network. In general, Rx-SafeNet site coordinators appeared to experience increased confidence in research engagement after joining the network. While respondents identified a number of benefits associated with network participation, concerns about potential time constraints remained a key barrier to participation. These findings will assist network leadership in identifying opportunities to positively increase member participation

  1. Band spectrum transformation and temperature dependences of thermoelectric power of Hg1-xRxBa2Ca2Cu3O8+δ system

    M. Vasyuk

    2011-03-01

    Full Text Available Temperature dependences of thermoelectric power S(T at T>Tc of the Hg-based high temperature superconductors Hg1-xRxBa2Ca2Cu3O8+δ (R=Re, Pb have been analyzed with accounting for strong scattering of charge carriers. Transformation of parameters of a narrow conducting band in the region of the Fermi level was studied. The existence of correlation between the effective bandwidth and the temperature of a superconductive transition Tc is shown.

  2. Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, Anke; Bours, Martijn Jl; Jørgensen, Niklas R

    2013-01-01

    of these two receptors on osteoporosis risk. Patients with fracture (690 females and 231 males, aged ≥50 years) were genotyped for three non-synonymous P2X ( 4 ) R SNPs. Bone mineral density (BMD) was measured at the total hip, lumbar spine, and femoral neck. Subject carrying the variant allele of the Tyr315...... of non-synonymous polymorphisms in the P2RX ( 4 ) and the risk of osteoporosis, suggesting a role of the P2X ( 4 ) R in the regulation of bone mass....

  3. Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains.

    Kanamori, Hajime; Parobek, Christian M; Juliano, Jonathan J; Johnson, James R; Johnston, Brian D; Johnson, Timothy J; Weber, David J; Rutala, William A; Anderson, Deverick J

    2017-08-01

    Escherichia coli sequence type 131 (ST131) predominates globally among multidrug-resistant (MDR) E. coli strains. We used whole-genome sequencing (WGS) to investigate 63 MDR E. coli isolates from 7 North Carolina community hospitals (2010 to 2015). Of these, 39 (62%) represented ST131, including 37 (95%) from the ST131- H 30R subclone: 10 (27%) from its H 30R1 subset and 27 (69%) from its H 30Rx subset. ST131 core genomes differed by a median of 15 (range, 0 to 490) single-nucleotide variants (SNVs) overall versus only 7 within H 30R1 (range, 3 to 12 SNVs) and 11 within H 30Rx (range, 0 to 21). The four isolates with identical core genomes were all H 30Rx. Epidemiological and clinical characteristics did not vary significantly by strain type, but many patients with MDR E. coli or H 30Rx infection were critically ill and had poor outcomes. H 30Rx isolates characteristically exhibited fluoroquinolone resistance and CTX-M-15 production, had a high prevalence of trimethoprim-sulfamethoxazole resistance (89%), sul1 (89%), and dfrA17 (85%), and were enriched for specific virulence traits, and all qualified as extraintestinal pathogenic E. coli The high overall prevalence of CTX-M-15 appeared to be possibly attributable to its association with the ST131- H 30Rx subclone and IncF[F2:A1:B-] plasmids. Some phylogenetically clustered non-ST131 MDR E. coli isolates also had distinctive serotypes/ fimH types, fluoroquinolone mutations, CTX-M variants, and IncF types. Thus, WGS analysis of our community hospital source MDR E. coli isolates suggested ongoing circulation and differentiation of E. coli ST131 subclones, with clonal segregation of CTX-M variants, other resistance genes, Inc-type plasmids, and virulence genes. Copyright © 2017 American Society for Microbiology.

  4. PROBING THE EXTREME REALM OF ACTIVE GALACTIC NUCLEUS FEEDBACK IN THE MASSIVE GALAXY CLUSTER, RX J1532.9+3021

    Hlavacek-Larrondo, J.; Allen, S. W.; Canning, R. E. A.; Werner, N.; Ehlert, S.; Von der Linden, A. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, 452 Lomita Mall, Stanford, CA 94305-4085 (United States); Taylor, G. B.; Grimes, C. K. [Department of Physics and Astronomy, University of New-Mexico, Albuquerque, NM 87131 (United States); Fabian, A. C. [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom); Sanders, J. S., E-mail: juliehl@stanford.edu [Max-Planck-Institut fur extraterrestrische Physik (MPE), Giessenbachstrasse, D-85748 Garching (Germany)

    2013-11-10

    We present a detailed Chandra, XMM-Newton, Very Large Array (VLA) and Hubble Space Telescope analysis of one of the strongest cool core clusters known, RX J1532.9+3021 (z = 0.3613). Using new, deep 90 ks Chandra observations, we confirm the presence of a western X-ray cavity or bubble, and report on a newly discovered eastern X-ray cavity. The total mechanical power associated with these active galactic nucleus (AGN) driven outflows is (22 ± 9) × 10{sup 44} erg s{sup –1}, and is sufficient to offset the cooling, indicating that AGN feedback still provides a viable solution to the cooling flow problem even in the strongest cool core clusters. Based on the distribution of the optical filaments, as well as a jet-like structure seen in the 325 MHz VLA radio map, we suggest that the cluster harbors older outflows along the north to south direction. The jet of the central AGN is therefore either precessing or sloshing-induced motions have caused the outflows to change directions. There are also hints of an X-ray depression to the north aligned with the 325 MHz jet-like structure, which might represent the highest redshift ghost cavity discovered to date. We further find evidence of a cold front (r ≈ 65 kpc) that coincides with the outermost edge of the western X-ray cavity and the edge of the radio mini-halo. The common location of the cold front with the edge of the radio mini-halo supports the idea that the latter originates from electrons being reaccelerated due to sloshing-induced turbulence. Alternatively, its coexistence with the edge of the X-ray cavity may be due to cool gas being dragged out by the outburst. We confirm that the central AGN is highly sub-Eddington and conclude that a >10{sup 10} M{sub ☉} or a rapidly spinning black hole is favored to explain both the radiative-inefficiency of the AGN and the powerful X-ray cavities.

  5. High Line

    Kiib, Hans

    2015-01-01

    At just over 10 meters above street level, the High Line extends three kilometers through three districts of Southwestern Manhattan in New York. It consists of simple steel construction, and previously served as an elevated rail line connection between Penn Station on 34th Street and the many....... The High Line project has been carried out as part of an open conversion strategy. The result is a remarkable urban architectural project, which works as a catalyst for the urban development of Western Manhattan. The greater project includes the restoration and reuse of many old industrial buildings...

  6. Gum-compliant uncertainty propagations for Pu and U concentration measurements using the 1st-prototype XOS/LANL hiRX instrument; an SRNL H-Canyon Test Bed performance evaluation project

    Holland, Michael K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); O' Rourke, Patrick E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-05-04

    An SRNL H-Canyon Test Bed performance evaluation project was completed jointly by SRNL and LANL on a prototype monochromatic energy dispersive x-ray fluorescence instrument, the hiRX. A series of uncertainty propagations were generated based upon plutonium and uranium measurements performed using the alpha-prototype hiRX instrument. Data reduction and uncertainty modeling provided in this report were performed by the SRNL authors. Observations and lessons learned from this evaluation were also used to predict the expected uncertainties that should be achievable at multiple plutonium and uranium concentration levels provided instrument hardware and software upgrades being recommended by LANL and SRNL are performed.

  7. Cholestatic Jaundice With the Use of Methylstenbolone and Dymethazine, Designer Steroids Found in Super DMZ Rx 2.0 “Nutritional Supplement”

    Priscilla Agbenyefia BA

    2014-04-01

    Full Text Available “Nutritional supplements” that promise an increase in muscle mass and strength are becoming a go to item as enhancing one’s physical appearance becomes a more important part of our society. This is alarming because many of these nutritional supplements rely on androgen precursors to deliver their promises, without adequately informing consumers of the potential side effects of such agents. These products may conceal the presence of potent androgens to avoid regulatory sanctions and become more appealing to consumers. Recent reports have shown that some products marketed as “nutritional supplements” have been found to contain androgenic anabolic steroids. Methylstenbolone and dymethazine are new androgenic anabolic steroids currently gaining popularity among body builders for their performance-enhancing properties and rapid effects on muscle mass. These agents are found together in Super DMZ Rx 2.0, a “dietary supplement” for bodybuilders. Here we report the first case of Super DMZ Rx 2.0–induced cholestatic jaundice in a 26-year-old previously healthy Caucasian male, who took the supplement according to the manufacturer’s instructions for 30 days.

  8. Disconnection of Cobe SMARxT® Tubing from the Venous Outlet of the Terumo Capiox® SX25RX Oxygenator During Cardiopulmonary Bypass

    Ottens, Jane; Baker, Robert A.; Sanderson, Andrew J.; Newland, Richard F.

    2010-01-01

    Abstract: The use of surface modified, biocompatible tubing in cardiopulmonary bypass has been reported to decrease the inflammatory responses caused by blood contact with the non endothelial surface of poly vinyl chloride (PVC) tubing. The combination of advances in biocompatible tubing and increased affordability resulted in a change to our cardiopulmonary bypass circuit, with the Terumo Capiox® SX25 oxygenator and Cobe PVC tubing being replaced with a Terumo Capiox® SX25RX (with X coating) and Cobe SMARxT® tubing. Prior to the introduction of the coated oxygenator, no connection problems had been evident. One unrelated disconnection involving coated tubing was reported in June 2005 to the Australian and New Zealand College of Perfusionists Perfusion Incident Reporting System. At this time we revised all of our set up protocols and the recommended actions from manufacturers. We further report three separate incidents of pump boot disconnection from the venous reservoir outlet of the oxygenator during bypass (that occurred within a 13-month period), and an outline of immediate and prospective evaluation of the probable cause. We propose that SMARxT® 3/8″ × 3/32″ tubing should not be used on the venous outlet connector of Terumo Capiox® SX25RX oxygenators. It appears as though the design of the outlet combined with the properties of SMARxT® tubing may contribute to the disconnection. PMID:20648902

  9. Disconnection of Cobe SMARxT tubing from the venous outlet of the Terumo Capiox SX25RX oxygenator during cardiopulmonary bypass.

    Ottens, Jane; Baker, Robert A; Sanderson, Andrew J; Newland, Richard F

    2010-06-01

    The use of surface modified, biocompatible tubing in cardiopulmonary bypass has been reported to decrease the inflammatory responses caused by blood contact with the non endothelial surface of poly vinyl chloride (PVC) tubing. The combination of advances in biocompatible tubing and increased affordability resulted in a change to our cardiopulmonary bypass circuit, with the Terumo Capiox SX25 oxygenator and Cobe PVC tubing being replaced with a Terumo Capiox SX25RX (with X coating) and Cobe SMARxT tubing. Prior to the introduction of the coated oxygenator, no connection problems had been evident. One unrelated disconnection involving coated tubing was reported in June 2005 to the Australian and New Zealand College of Perfusionists Perfusion Incident Reporting System. At this time we revised all of our set up protocols and the recommended actions from manufacturers. We further report three separate incidents of pump boot disconnection from the venous reservoir outlet of the oxygenator during bypass (that occurred within a 13-month period), and an outline of immediate and prospective evaluation of the probable cause. We propose that SMARxT 3/8" x 3/32" tubing should not be used on the venous outlet connector of Terumo Capiox SX25RX oxygenators. It appears as though the design of the outlet combined with the properties of SMARxT tubing may contribute to the disconnection.

  10. Resolvin E1 (RX-10001) reduces corneal epithelial barrier disruption and protects against goblet cell loss in a murine model of dry eye.

    de Paiva, Cintia S; Schwartz, C Eric; Gjörstrup, Per; Pflugfelder, Stephen C

    2012-11-01

    Resolvin E1 (RvE1; RX-10001) belongs to a new class of endogenous immunoregulating mediators, originally identified as a metabolite of the omega-3 polyunsaturated fatty acid, eicosapentaenoic acid. Based on its proven efficacy in models of chronic inflammation, this study investigated the efficacy of resolvin E1 in a murine model of dry eye. C57/B6 mice, aged 6 to 8 weeks, were treated with systemic scopolamine and exposed to air draft and low humidity for 16 hours/day for 5 days and allocated to the following groups: unexposed controls, disease controls, treatment with vehicle or RvE1 delivered topically as its methyl ester prodrug, RX-10005, to enhance corneal surface penetration. Treatment was initiated at the time of desiccating stress induction. Treatment efficacy was assessed by corneal permeability using Oregon Green Dextran and by conjunctival goblet cell density using periodic acid-Schiff reagent. RvE1 reduced the increase in corneal staining by 80% compared with untreated disease controls. Goblet cell density was reduced by 20% in disease controls but fully maintained in the group receiving RvE1. RvE1, delivered as its methyl ester prodrug, improved the outcome measures of corneal staining and goblet cell density in this murine model of dry eye, indicating the potential utility of endogenous resolvins and resolvin analogues in the treatment of dry eye.

  11. World lines.

    Waser Jürgen; Fuchs Raphael; Ribicic Hrvoje; Schindler Benjamin; Blöschl Günther; Gröller Eduard

    2010-01-01

    In this paper we present World Lines as a novel interactive visualization that provides complete control over multiple heterogeneous simulation runs. In many application areas decisions can only be made by exploring alternative scenarios. The goal of the suggested approach is to support users in this decision making process. In this setting the data domain is extended to a set of alternative worlds where only one outcome will actually happen. World Lines integrate simulation visualization and...

  12. RX for Writer's Block.

    Tompkins, Gail E.; Camp, Donna J.

    1988-01-01

    Describes four prewriting techniques that elementary and middle grade students can use to gather and organize ideas for writing, and by so doing, cure writer's block. Techniques discussed are: (1) brainstorming; (2) clustering; (3) freewriting; and (4) cubing.

  13. RxJava essentials

    Morgillo, Ivan

    2015-01-01

    If you are an experienced Java developer, reactive programming will give you a new way to approach scalability and concurrency in your backend systems, without forcing you to switch programming languages.

  14. RX in the Classroom.

    Ladd, Frances T.; And Others

    1980-01-01

    Presented is a chart for educators on common medications which may be taken by students for such health problems as diabetes, hypertension, epilepsy, asthma, juvenile rheumatoid arthritis, and leukemia. The possible side effects of each drug are explained. (SJL)

  15. Bloqueo aurículo-ventricular congénito completo: Reporte de un caso y revisión de la literatura Congenital complete atrioventricular block: eport of one case and literature review

    Alejandro Díaz D

    2008-02-01

    Full Text Available El bloqueo aurículo-ventricular completo congénito, es una entidad poco común, que presenta alta morbilidad y mortalidad con incidencia real que permanece desconocida y requiere alto índice de sospecha para su diagnóstico y, por ende, su temprana intervención. Se observa en hijos de madres con enfermedades autoinmunes del tejido conectivo, en especial, lupus eritematoso sistémico cuando su aparición es congénita. A nivel postnatal, es más frecuente que ocurra por cardiopatías congénitas. También puede manifestarse en corazones normales desde el punto de vista estructural. El hallazgo clínico característico es bradicardia persistente que se manifiesta desde la vida intrauterina y repercute en la estabilidad circulatoria del feto llegando a producir hidrops, complicación seria y letal. Después del nacimiento aparece igualmente con bradicardia que puede o no descompensar la parte hemodinámica del paciente. El diagnóstico se hace por sospecha clínica, con ecocardiografía fetal y postnatal, electrocardiograma y detección de anticuerpos maternos tipo antiRo y antiLa. La implantación de un marcapasos es el tratamiento definitivo que contribuye a mejorar la sobrevida y el pronóstico de estos pacientes. Se presenta el caso de una paciente prematura, de 31 semanas, debido a hidrops no inmune, en quien se diagnosticó bloqueo aurículo-ventricular completo congénito secundario a lupus materno confirmado por anticuerpos anti-nucleares francamente positivos y anticuerpos antiRo y antiLa positivos, quien recibió manejo con soporte inotrópico y posterior implantación de marcapasos. Presentó mejoría completa de la falla cardiaca y se remitió hacia otra institución para manejo convencional del prematuro.Complete congenital atrioventricular block is a rare entity that has a high morbidity and mortality. Its real incidence remains unknown and a high suspicion index is needed for its diagnosis and consequently for its early

  16. Silver linings.

    Bultas, Margaret W; Pohlman, Shawn

    2014-01-01

    The purpose of this interpretive phenomenological study was to gain a better understanding of the experiences of 11 mothers of preschool children with autism spectrum disorder (ASD). Mothers were interviewed three times over a 6 week period. Interviews were analyzed using interpretive methods. This manuscript highlights one particular theme-a positive perspective mothers described as the "silver lining." This "silver lining" represents optimism despite the adversities associated with parenting a child with ASD. A deeper understanding of this side of mothering children with ASD may help health care providers improve rapport, communication, and result in more authentic family centered care. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Convergencia de los grupos armados organizados al margen de la ley en la minería aurífera aluvial en la subregión del Bajo Cauca antioqueño

    Isabel Esther Maldonado Sarmiento

    2014-12-01

    Full Text Available Se tuvo como propósito describir la minería aurífera aluvial y la convergencia de los grupos armados organizados al margen de la ley en la subregión del Bajo Cauca antioqueño. Los resultados obtenidos se centran en identificar el marco teórico, proponer un concepto y describir los rasgos característicos de esta actividad desde la perspectiva criminal. Lo anterior se logró a partir de una aproximación conceptual y la representación fáctica de la información obtenida, a través de la revisión teórica, la consulta bibliográfica y el trabajo de campo, en el que se aplicaron diferentes técnicas de recolección, como la entrevista semiestructurada, el grupo focal y la observación no participante. El precedente para comenzar la indagación se centró en la ausencia de un concepto que delimite los tipos de minería y la confusión que existe al colocar a todos los mineros ilegales, informales y criminales dentro una misma categoría. Además, se busca suscitar una reflexión crítica respecto a los posibles riesgos y amenazas que genera la convergencia de estos grupos en los tipos de minería, con el control social y territorial, el poder, la coacción y la institucionalización de actividades económicas criminales.

  18. Deeper H.E.S.S. observations of Vela Junior (RX J0852.0-4622): Morphology studies and resolved spectroscopy

    H.E.S.S. Collaboration; Abdalla, H.; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Angüner, E. O.; Arakawa, M.; Arrieta, M.; Aubert, P.; Backes, M.; Balzer, A.; Barnard, M.; Becherini, Y.; Becker Tjus, J.; Berge, D.; Bernhard, S.; Bernlöhr, K.; Blackwell, R.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Bregeon, J.; Brun, F.; Brun, P.; Bryan, M.; Büchele, M.; Bulik, T.; Capasso, M.; Carr, J.; Casanova, S.; Cerruti, M.; Chakraborty, N.; Chalme-Calvet, R.; Chaves, R. C. G.; Chen, A.; Chevalier, J.; Chrétien, M.; Coffaro, M.; Colafrancesco, S.; Cologna, G.; Condon, B.; Conrad, J.; Cui, Y.; Davids, I. D.; Decock, J.; Degrange, B.; Deil, C.; Devin, J.; deWilt, P.; Dirson, L.; Djannati-Ataï, A.; Domainko, W.; Donath, A.; Drury, L. O.'C.; Dutson, K.; Dyks, J.; Edwards, T.; Egberts, K.; Eger, P.; Ernenwein, J.-P.; Eschbach, S.; Farnier, C.; Fegan, S.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Funk, S.; Füßling, M.; Gabici, S.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Gottschall, D.; Goyal, A.; Grondin, M.-H.; Hahn, J.; Haupt, M.; Hawkes, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hinton, J. A.; Hofmann, W.; Hoischen, C.; Holler, M.; Horns, D.; Ivascenko, A.; Iwasaki, H.; Jacholkowska, A.; Jamrozy, M.; Janiak, M.; Jankowsky, D.; Jankowsky, F.; Jingo, M.; Jogler, T.; Jouvin, L.; Jung-Richardt, I.; Kastendieck, M. A.; Katarzyński, K.; Katsuragawa, M.; Katz, U.; Kerszberg, D.; Khangulyan, D.; Khélifi, B.; Kieffer, M.; King, J.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kolitzus, D.; Komin, Nu.; Krakau, S.; Kraus, M.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lau, J.; Lees, J.-P.; Lefaucheur, J.; Lefranc, V.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Leser, E.; Lohse, T.; Lorentz, M.; Liu, R.; López-Coto, R.; Lypova, I.; Marandon, V.; Marcowith, A.; Mariaud, C.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; Meintjes, P. J.; Meyer, M.; Mitchell, A. M. W.; Moderski, R.; Mohamed, M.; Mohrmann, L.; Morå, K.; Moulin, E.; Murach, T.; Nakashima, S.; de Naurois, M.; Niederwanger, F.; Niemiec, J.; Oakes, L.; O'Brien, P.; Odaka, H.; Öttl, S.; Ohm, S.; Ostrowski, M.; Oya, I.; Padovani, M.; Panter, M.; Parsons, R. D.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perennes, C.; Petrucci, P.-O.; Peyaud, B.; Piel, Q.; Pita, S.; Poon, H.; Prokhorov, D.; Prokoph, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Richter, S.; Rieger, F.; Romoli, C.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Saito, S.; Salek, D.; Sanchez, D. A.; Santangelo, A.; Sasaki, M.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwemmer, S.; Seglar-Arroyo, M.; Settimo, M.; Seyffert, A. S.; Shafi, N.; Shilon, I.; Simoni, R.; Sol, H.; Spanier, F.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stycz, K.; Sushch, I.; Takahashi, T.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tibaldo, L.; Tiziani, D.; Tluczykont, M.; Trichard, C.; Tsuji, N.; Tuffs, R.; Uchiyama, Y.; van der Walt, D. J.; van Eldik, C.; van Rensburg, C.; van Soelen, B.; Vasileiadis, G.; Veh, J.; Venter, C.; Viana, A.; Vincent, P.; Vink, J.; Voisin, F.; Völk, H. J.; Vuillaume, T.; Wadiasingh, Z.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zaborov, D.; Zacharias, M.; Zanin, R.; Zdziarski, A. A.; Zech, A.; Zefi, F.; Ziegler, A.; Żywucka, N.

    2018-04-01

    Aims: We study γ-ray emission from the shell-type supernova remnant (SNR) RX J0852.0-4622 to better characterize its spectral properties and its distribution over the SNR. Methods: The analysis of an extended High Energy Spectroscopic System (H.E.S.S.) data set at very high energies (E > 100 GeV) permits detailed studies, as well as spatially resolved spectroscopy, of the morphology and spectrum of the whole RX J0852.0-4622 region. The H.E.S.S. data are combined with archival data from other wavebands and interpreted in the framework of leptonic and hadronic models. The joint Fermi-LAT-H.E.S.S. spectrum allows the direct determination of the spectral characteristics of the parent particle population in leptonic and hadronic scenarios using only GeV-TeV data. Results: An updated analysis of the H.E.S.S. data shows that the spectrum of the entire SNR connects smoothly to the high-energy spectrum measured by Fermi-LAT. The increased data set makes it possible to demonstrate that the H.E.S.S. spectrum deviates significantly from a power law and is well described by both a curved power law and a power law with an exponential cutoff at an energy of Ecut = (6.7 ± 1.2stat ± 1.2syst) TeV. The joint Fermi-LAT-H.E.S.S. spectrum allows the unambiguous identification of the spectral shape as a power law with an exponential cutoff. No significant evidence is found for a variation of the spectral parameters across the SNR, suggesting similar conditions of particle acceleration across the remnant. A simple modeling using one particle population to model the SNR emission demonstrates that both leptonic and hadronic emission scenarios remain plausible. It is also shown that at least a part of the shell emission is likely due to the presence of a pulsar wind nebula around PSR J0855-4644. A FITS image of the region of interest and two text files describing the H.E.S.S. spectrum of RX J0852.0-4622 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http

  19. Tapchanger controls : use and abuse in volt/var management (line drop compensation applications)

    Jauch, E.T. [Beckwith Electric Company Inc., Largo, FL (United States)

    2007-07-01

    Traditional line drop compensation (LDC) is a feature that has been included in virtually every automatic tapchanger control for over 50 years. This function was designed to accommodate a specific distribution system application that differs from most applications in today's power systems. The application and setting of the LDC function must consider the overall control operation of the distribution system during emergency or contingency system configurations as well as additional control function interactions. This paper discussed several of these considerations and described a second type of LDC philosophy offered in a few modern controls. With the LDC-Z method, the control setting method and the response to distribution system equipment switching can be quite different. The paper discussed the basic control features and operation including the traditional RX LDC in both normal operating and abnormal distribution system conditions including unexpected system voltage results occurring on present power systems from LDC misuse. It also presented a description of the LDC-Z method and how settings are determined. The more appropriate applications for each method were described. The paper also identified the most common method of providing backup protection against LDC overcompensation for both LDC RX and LDC-Z methods and its importance. A description of LDC applicability for different system configurations and conditions including paralleled transformers, reverse power situations, network and distributed generation applications as well as the use of LDC RX settings to attempt to provide emergency transformer paralleling control were also provided. It was concluded that the relatively new LDC-Z compensation was better applied in many substation applications and automatic system equipment operations could result in different system operating conditions. 11 figs.

  20. Secular Decrease of the Spin Period of the White Dwarf in the Asynchronous AM HER Binary RX J1940.1-1025

    Staubert, Ruediger

    We propse to perform four 1 day observations of the near-synchronous AM Her binary RX J1940.1-1025, spread equally over Cycle 6, and at phases near 0.25 with respect to its 50 day beat period. The orbital period is 12116.3 s and the spin period of the white dawarf is 12150.7 s. We have evidence for a secular decrease of this spin period at a rate of 5 10^(-9), which is mainly based on optical data. X-ray data (from ROSAT and RXTE) are sparse, but indicate that there might be a systematic phase shift of a feature (the so-called "trough") in the flux profiles between optical and X-rays. If this shift is confirmed and measured accurately, optical and X-ray data can be confidently combined and the synchronisation time scale (about 200 years) determined.

  1. Measurement of the X-ray proper motion in the south-east rim of RX J1713.7-3946

    Acero, Fabio; Katsuda, Satoru; Ballet, Jean; Petre, Robert

    2017-01-01

    We report on the first proper motion measurement in the supernova remnant RX J1713.7-3946 using the XMM-Newton X-ray telescope on a 13 yr time interval. This expansion measurement is carried out in the south-east region of the remnant, where two sharp filament structures are observed. For the outermost filament, the proper motion is arcsec yr-1 which is equivalent to a shock speed of 3500 km s-1 at a distance of 1 kpc. In contrast with the bright north-west region, where the shock is interacting with the border of the cavity, the shock in the south-east region is probably expanding in the original ambient medium carved by the progenitor and can be used to derive the current density at the shock and the age of the remnant. In the case where the shock is evolving in a wind profile (ρ ∝ r- s, s = 2) or in a uniform medium (s = 0), we estimate an age of 2300 yr and 1800 yr respectively for an ejecta power-law index of n = 9. The specific case of an ejecta power-law index of n = 7, and s = 0, yields an age of 1500 yr, which would reconcile RX J1713.7-3946 with the historical records of SN 393. In all scenarios, we derive similar upstream densities of the order of 0.01 cm-3, compatible with the lack of thermal X-rays from the shocked ambient medium.

  2. Structural determinants at the interface of the ARC2 and leucine-rich repeat domains control the activation of the plant immune receptors Rx1 and Gpa2.

    Slootweg, Erik J; Spiridon, Laurentiu N; Roosien, Jan; Butterbach, Patrick; Pomp, Rikus; Westerhof, Lotte; Wilbers, Ruud; Bakker, Erin; Bakker, Jaap; Petrescu, Andrei-José; Smant, Geert; Goverse, Aska

    2013-07-01

    Many plant and animal immune receptors have a modular nucleotide-binding-leucine-rich repeat (NB-LRR) architecture in which a nucleotide-binding switch domain, NB-ARC, is tethered to a LRR sensor domain. The cooperation between the switch and sensor domains, which regulates the activation of these proteins, is poorly understood. Here, we report structural determinants governing the interaction between the NB-ARC and LRR in the highly homologous plant immune receptors Gpa2 and Rx1, which recognize the potato cyst nematode Globodera pallida and Potato virus X, respectively. Systematic shuffling of polymorphic sites between Gpa2 and Rx1 showed that a minimal region in the ARC2 and N-terminal repeats of the LRR domain coordinate the activation state of the protein. We identified two closely spaced amino acid residues in this region of the ARC2 (positions 401 and 403) that distinguish between autoactivation and effector-triggered activation. Furthermore, a highly acidic loop region in the ARC2 domain and basic patches in the N-terminal end of the LRR domain were demonstrated to be required for the physical interaction between the ARC2 and LRR. The NB-ARC and LRR domains dissociate upon effector-dependent activation, and the complementary-charged regions are predicted to mediate a fast reassociation, enabling multiple rounds of activation. Finally, we present a mechanistic model showing how the ARC2, NB, and N-terminal half of the LRR form a clamp, which regulates the dissociation and reassociation of the switch and sensor domains in NB-LRR proteins.

  3. Fixed-Node Diffusion Quantum Monte Carlo Method on Dissociation Energies and Their Trends for R-X Bonds (R = Me, Et, i-Pr, t-Bu).

    Hou, Aiqiang; Zhou, Xiaojun; Wang, Ting; Wang, Fan

    2018-05-15

    Achieving both bond dissociation energies (BDEs) and their trends for the R-X bonds with R = Me, Et, i-Pr, and t-Bu reliably is nontrivial. Density functional theory (DFT) methods with traditional exchange-correlation functionals usually have large error on both the BDEs and their trends. The M06-2X functional gives rise to reliable BDEs, but the relative BDEs are determined not as accurately. More demanding approaches such as some double-hybrid functionals, for example, G4 and CCSD(T), are generally required to achieve the BDEs and their trends reliably. The fixed-node diffusion quantum Monte Carlo method (FN-DMC) is employed to calculated BDEs of these R-X bonds with X = H, CH 3 , OCH 3 , OH, and F in this work. The single Slater-Jastrow wave function is adopted as trial wave function, and pseudopotentials (PPs) developed for quantum Monte Carlo calculations are chosen. Error of these PPs is modest in wave function methods, while it is more pronounced in DFT calculations. Our results show that accuracy of BDEs with FN-DMC is similar to that of M06-2X and G4, and trends in BDEs are calculated more reliably than M06-2X. Both BDEs and trends in BDEs of these bonds are reproduced reasonably with FN-DMC. FN-DMC using PPs can thus be applied to BDEs and their trends of similar chemical bonds in larger molecules reliably and provide valuable information on properties of these molecules.

  4. CORE-COLLAPSE MODEL OF BROADBAND EMISSION FROM SNR RX J1713.7–3946 WITH THERMAL X-RAYS AND GAMMA RAYS FROM ESCAPING COSMIC RAYS

    Ellison, Donald C.; Slane, Patrick; Patnaude, Daniel J.; Bykov, Andrei M.

    2012-01-01

    We present a spherically symmetric, core-collapse model of SNR RX J1713.7–3946 that includes a hydrodynamic simulation of the remnant evolution coupled to the efficient production of cosmic rays (CRs) by nonlinear diffusive shock acceleration. High-energy CRs that escape from the forward shock (FS) are propagated in surrounding dense material that simulates either a swept-up, pre-supernova shell or a nearby molecular cloud. The continuum emission from trapped and escaping CRs, along with the thermal X-ray emission from the shocked heated interstellar medium behind the FS, integrated over the remnant, is compared against broadband observations. Our results show conclusively that, overall, the GeV-TeV emission is dominated by inverse-Compton from CR electrons if the supernova is isolated regardless of its type, i.e., not interacting with a >>100 M ☉ shell or cloud. If the supernova remnant is interacting with a much larger mass ∼> 10 4 M ☉ , pion decay from the escaping CRs may dominate the TeV emission, although a precise fit at high energy will depend on the still uncertain details of how the highest energy CRs are accelerated by, and escape from, the FS. Based on morphological and other constraints, we consider the 10 4 M ☉ pion-decay scenario highly unlikely for SNR RX J1713.7–3946 regardless of the details of CR escape. Importantly, even though CR electrons dominate the GeV-TeV emission, the efficient production of CR ions is an essential part of our leptonic model.

  5. production lines

    Jingshan Li

    2000-01-01

    Full Text Available In this work, serial production lines with finished goods buffers operating in the pull regime are considered. The machines are assumed to obey Bernoulli reliability model. The problem of satisfying customers demand is addressed. The level of demand satisfaction is quantified by the due-time performance (DTP, which is defined as the probability to ship to the customer a required number of parts during a fixed time interval. Within this scenario, the definitions of DTP bottlenecks are introduced and a method for their identification is developed.

  6. Line facilities outline

    1998-08-01

    This book deals with line facilities. The contents of this book are outline line of wire telecommunication ; development of line, classification of section of line and theory of transmission of line, cable line ; structure of line, line of cable in town, line out of town, domestic cable and other lines, Optical communication ; line of optical cable, transmission method, measurement of optical communication and cable of the sea bottom, Equipment of telecommunication line ; telecommunication line facilities and telecommunication of public works, construction of cable line and maintenance and Regulation of line equipment ; regulation on technique, construction and maintenance.

  7. Evaluación de la concentración de mercurio en arroz (Oryza sativa crudo y cocido procedente del municipio de San Marcos- Sucre y zona aurífera del municipio de Ayapel - Córdoba

    Marcela P. Argumedo G.

    2015-08-01

    Full Text Available Introducción: Los metales se encuentran en todos los alimentos, siendo de mayor preocupación la presencia de metales tóxicos como el mercurio, debido a los efectos adversos que causa en la salud del hombre, lo que lo ha convertido en un grave problema de salud pública. Objetivo: Evaluar la concentración de mercurio en arroz (Oryza sativa crudo y cocido procedente del municipio de San Marcos - Sucre y zona aurífera del municipio de Ayapel - Córdoba. Metodología: El presente estudio es de tipo exploratorio y experimental. La toma de muestras fue realizada en tiempo de recolección del arroz (septiembre y se tomaron tres repeticiones de cada tipo o variedad de arroz (Fedearroz 2000 - LD 473. La cocción del alimento fue realizada en el laboratorio en condiciones similares a las utilizadas por habitantes de las comunidades donde fueron recolectadas las muestras. Para los análisis de relación estadística entre los tratamientos de cocción y la concentración de mercurio total en muestras, fue realizado un análisis de correlación simple. La determinación de diferencias estadísticamente significativas entre las muestras de arroz crudo y cocido fue realizada mediante un t-test y Anova. Resultados: Se presentaron concentraciones bajas de mercurio total y metilmercurio en las muestras de arroz crudo y cocido. Además, fue detectado que el proceso de cocción del alimento disminuye las concentraciones de HgT, en los diferentes tratamientos de tiempo de cocción. Conclusiones: Los habitantes de los municipios en estudio están expuestos a concentraciones mínimas de mercurio que podrían ser perjudiciales para su salud, debido a la alta ingesta de este cereal en la dieta de las comunidades.

  8. Central nervous system abnormalities in patients with oculo-auriculo-vertebral spectrum (Goldenhar syndrome Anormalidades do sistema nervoso central em pacientes com espectro óculo-aurículo-vertebral (síndrome de Goldenhar

    Rafael Fabiano Machado Rosa

    2010-02-01

    Full Text Available OBJECTIVE: To describe the central nervous system (CNS alterations present in a sample of oculo-auriculo-vertebral spectrum (OAVS patients, trying to correlate them with other clinical features. METHOD: Seventeen patients with diagnosis of OAVS were evaluated. All presented radiological evaluation of the CNS, normal GTG-Banding karyotype and clinical features involving at least two from the four following areas: oro-cranio-facial, ocular, auricular and vertebral. RESULTS: CNS alterations were verified in eight from seventeen patients (47%. Diffuse cerebral hypoplasia, dilated lateral cerebral ventricles (asymptomatic hydrocephalus, corpus callosum dysgenesis and frontal hypodensities were the most frequent abnormalities. Presence of ophthalmologic abnormalities was the only clinical association observed, being significantly more frequent among patients with cerebral alterations (63% versus 11%. CONCLUSION: CNS abnormalities are frequent in patients with OAVS, especially in carriers of ophthalmologic alterations. However, the absence of detectable cerebral abnormalities did not exclude the possibility that these subjects will subsequently present neurological symptoms.OBJETIVO: Descrever as alterações do sistema nervoso central (SNC presentes em uma amostra de pacientes com espectro óculo-aurículo-vertebral (EOAV, tentando correlacioná-las com os demais achados clínicos. MÉTODO: Foram avaliados dezessete pacientes com diagnóstico de EOAV. Todos apresentavam avaliação radiológica do SNC, cariótipo por bandas GTG normal e achados clínicos em pelo menos duas das quatro das seguintes áreas: oro-crânio-facial, ocular, auricular e vertebral. RESULTADOS: Alterações do SNC foram verificadas em oito dos dezessete pacientes (47%. Hipoplasia cerebral difusa, dilatação dos ventrículos cerebrais laterais (hidrocefalia assintomática, disgenesia do corpo caloso e hipondesidades frontais foram as anormalidades mais frequentes. A presença de

  9. Resección de un carcinoma renal izquierdo con extensión trombótica hacia la aurícula derecha Resection of a left renal carcinoma with thrombotic extension to right atrium

    Alejandro Villar Inclán

    2010-09-01

    Full Text Available Se presenta el caso de un hombre de 59 años con diagnóstico de hipernefroma izquierdo y trombosis de la vena cava inferior con extensión hacia la aurícula derecha. Un equipo multidisciplinario realizó una nefrectomía radical izquierda, exposición de la vena cava inferior con técnica de piggyback, atriotomía derecha y cavotomía inferior para extracción del trombo, previo pinzamiento de la vena renal derecha y el hilio hepático. El tiempo quirúrgico total fue de 7 h 30 min. El procedimiento se realizó con anestesia general y un período mínimo de derivación cardiopulmonar. Se utilizó monitorización transoperatoria estandarizada de los parámetros vitales y además ecocardiografía transesofágica para la detección de la remoción completa del trombo y su extracción, así como posibles émbolos desprendidos. La evolución transoperatoria y posoperatoria fue satisfactoria. Se realiza una revisión de la literatura médica internacional sobre el tema y se ofrecen conclusiones.This is the male case aged 59 diagnosed with left hypernephroma and thrombosis of the inferior vena cava with extension to right atrium. A multidisciplinary staff performed a left radical nephrectomy, exposition of inferior vena cava using the piggyback technique, right atriotomy and inferior cavotomy for extension of thrombus and previous clamping of right renal vein and hepatic hilus. The total surgical time was of 7 hours and 30 minutes. The procedure was performed under general anesthesia and a minimal period of cardiopulmonary shunt. Standardized transoperative monitoring of vital parameters was used and also transesophageal echocardiography to detect the total removal of thrombus and its extraction, as well as the potential detached emboli. The transoperative and postoperative course was satisfactory. A review of the international medical literature on this subject was made offering conclusions.

  10. TIME VARIABILITY OF EMISSION LINES FOR FOUR ACTIVE T TAURI STARS. I. OCTOBER–DECEMBER IN 2010

    Chou, Mei-Yin; Takami, Michihiro; Karr, Jennifer L.; Shang Hsien; Liu, Hauyu Baobab; Manset, Nadine; Beck, Tracy; Pyo, Tae-Soo; Chen, Wen-Ping; Panwar, Neelam

    2013-01-01

    We present optical spectrophotometric monitoring of four active T Tauri stars (DG Tau, RY Tau, XZ Tau, RW Aur A) at high spectral resolution (R ∼> 1 × 10 4 ), to investigate the correlation between time variable mass ejection seen in the jet/wind structure of the driving source and time variable mass accretion probed by optical emission lines. This may allow us to constrain the understanding of the jet/wind launching mechanism, the location of the launching region, and the physical link with magnetospheric mass accretion. In 2010, observations were made at six different epochs to investigate how daily and monthly variability might affect such a study. We perform comparisons between the line profiles we observed and those in the literature over a period of decades and confirm the presence of time variability separate from the daily and monthly variability during our observations. This is so far consistent with the idea that these line profiles have a long-term variability (3-20 yr) related to episodic mass ejection suggested by the structures in the extended flow components. We also investigate the correlations between equivalent widths and between luminosities for different lines. We find that these correlations are consistent with the present paradigm of steady magnetospheric mass accretion and emission line regions that are close to the star.

  11. TIME VARIABILITY OF EMISSION LINES FOR FOUR ACTIVE T TAURI STARS. I. OCTOBER-DECEMBER IN 2010

    Chou, Mei-Yin; Takami, Michihiro; Karr, Jennifer L.; Shang Hsien; Liu, Hauyu Baobab [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan (China); Manset, Nadine [Canada-France-Hawaii Telescope, 65-1238 Mamalahoa Hwy, Kamuela, HI 96743 (United States); Beck, Tracy [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Pyo, Tae-Soo [Subaru Telescope, 650 North Aohoku Place, Hilo, HI 96720 (United States); Chen, Wen-Ping; Panwar, Neelam [Institute of Astronomy, National Central University, Taoyuan County 32001, Taiwan (China)

    2013-04-15

    We present optical spectrophotometric monitoring of four active T Tauri stars (DG Tau, RY Tau, XZ Tau, RW Aur A) at high spectral resolution (R {approx}> 1 Multiplication-Sign 10{sup 4}), to investigate the correlation between time variable mass ejection seen in the jet/wind structure of the driving source and time variable mass accretion probed by optical emission lines. This may allow us to constrain the understanding of the jet/wind launching mechanism, the location of the launching region, and the physical link with magnetospheric mass accretion. In 2010, observations were made at six different epochs to investigate how daily and monthly variability might affect such a study. We perform comparisons between the line profiles we observed and those in the literature over a period of decades and confirm the presence of time variability separate from the daily and monthly variability during our observations. This is so far consistent with the idea that these line profiles have a long-term variability (3-20 yr) related to episodic mass ejection suggested by the structures in the extended flow components. We also investigate the correlations between equivalent widths and between luminosities for different lines. We find that these correlations are consistent with the present paradigm of steady magnetospheric mass accretion and emission line regions that are close to the star.

  12. Parallel Lines

    James G. Worner

    2017-05-01

    Full Text Available James Worner is an Australian-based writer and scholar currently pursuing a PhD at the University of Technology Sydney. His research seeks to expose masculinities lost in the shadow of Australia’s Anzac hegemony while exploring new opportunities for contemporary historiography. He is the recipient of the Doctoral Scholarship in Historical Consciousness at the university’s Australian Centre of Public History and will be hosted by the University of Bologna during 2017 on a doctoral research writing scholarship.   ‘Parallel Lines’ is one of a collection of stories, The Shapes of Us, exploring liminal spaces of modern life: class, gender, sexuality, race, religion and education. It looks at lives, like lines, that do not meet but which travel in proximity, simultaneously attracted and repelled. James’ short stories have been published in various journals and anthologies.

  13. Cardiomiopatía hipertrófica y síndrome de Wolff-Parkinson-White con bloqueo aurículo-ventricular completo. Una extraña asociación: Reporte de un caso Hypertrophic cardiomyopathy and Wolff-Parkinson-White Syndrome with complete auriculoventricular block. A strange association: Report of one case

    Franco J Vallejo

    2007-12-01

    Full Text Available Paciente masculino de 22 años quien ingresa por episodio de síncope. En el electrocardiograma se encuentra patrón de Wolff-Parkinson-White y signos de sobrecarga auricular e hipertrofia ventricular izquierda con bloqueo aurículo-ventricular completo. El ecocardiograma transtorácico es compatible con cardiomiopatía hipertrófica no obstructiva. Se lleva a estudio electrofisiológico donde se encuentra pre-excitación por vía accesoria y bloqueo aurículo-ventricular infrahisiano; se realiza ablación y se implanta marcapasos bicameral.A 22 years old male patient is admitted for a syncope episode. An electrocardiogram shows a Wolff-Parkinson-White pattern and signs of auricular overload with left ventricular hypertrophy and complete auriculoventricular block. The transthoracic echocardiogram is compatible with non-obstructive hypertrophic cardiomyopathy. An electrophysiological study is carried out, finding pre-excitation through an accessory way and infra-His auriculoventricular block. An ablation is performed and a bicameral pacemaker is implanted.

  14. Anomalía del retorno venoso sistémico Drenaje anómalo de la vena cava superior derecha a la aurícula izquierda: Revisión de la literatura y reporte de caso Anomalous systemic venous return. Anomalous drainage of the right superior vena cava into the left atrium: Review of literature and case report

    Ríos Giovanny

    2012-06-01

    Full Text Available La anomalía total del retorno venoso sistémico tiene gran variedad de presentaciones; sin embargo, la patología de más baja frecuencia es el drenaje de vena cava superior derecha a la aurícula izquierda, hecho de peso para que en el mundo se reporten pocos casos. En la Fundación Clínica Abood Shaio se trató el caso de una paciente de seis años de edad con drenaje venoso total de cava superior derecha a la aurícula izquierda, mediante la técnica de movilización de cava superior y anastomosis cavo-atrial, y se obtuvieron buenos resultados. El caso es mención corresponde al número 21 en la literatura mundial.Total anomalous systemic venous return has a variety of presentations, being the drainage of right superior vena cava into the left atrium a low frequency condition. There are few reported cases in the world. In Shaio Clinic Foundation we have handled a case of total venous drainage of the right superior vena cava into the left atrium in a 6-year old girl, using the superior vena cava mobilization technique and cavo-atrial anastomosis, with good results. This case is reported as case number 21 in the world.

  15. VT Digital Line Graph Miscellaneous Transmission Lines

    Vermont Center for Geographic Information — (Link to Metadata) This datalayer is comprised of Miscellaineous Transmission Lines. Digital line graph (DLG) data are digital representations of cartographic...

  16. [Susceptibility to strategy of the drug component of the IPHCC+RxGroups classification system in a risk-adjusted morbidity compensation scheme--a conceptional and data-supported analysis].

    Behrend, C; Felder, S; Busse, R

    2007-01-01

    A report commissioned by the German Ministry of Health recommends to the existing scheme for calculating risk-adjusted transfers to sickness funds supplement with the IPHCC+RxGroups method. The method is based on inpatient diagnoses and prescribed drugs as health status measures deduced from prior use. The present study investigates the sickness fund's expected net return from gaming based on the drug component of the risk adjuster. The study explores three possible strategies using the RxGroups method. For the stimulations, insurees are assigned to additional indications or to higher valued RxGroups within the same indication. Then, costs and financial benefits attributable to the altered drug use are estimated and compared with the status quo. The study uses 2000 and 2001 sample data of more than 370,000 insurees of Germany's company-based sickness funds system (BKK). While upgrading increases overall costs, it can be beneficial for the individual sickness funds. Their net return crucially depends on the number of sickness funds gaming the system: the more participating in the game, the smaller is the average net return. Moreover, not participating often is even worse, which in turn points to a prisoner's dilemma. When extending the risk adjustment scheme in social health insurance, the German legislator should take into account the perverse incentives of risk adjusters such as the described prescription drug model.

  17. In vitro evaluation of gaseous microemboli handling of cardiopulmonary bypass circuits with and without integrated arterial line filters.

    Liu, Saifei; Newland, Richard F; Tully, Phillip J; Tuble, Sigrid C; Baker, Robert A

    2011-09-01

    The delivery of gaseous microemboli (GME) by the cardiopulmonary bypass circuit should be minimized whenever possible. Innovations in components, such as the integration of arterial line filter (ALF) and ALFs with reduced priming volumes, have provided clinicians with circuit design options. However, before adopting these components clinically, their GME handling ability should be assessed. This study aims to compare the GME handling ability of different oxygenator/ALF combinations with our currently utilized combination. Five commercially available oxygenator/ALF combinations were evaluated in vitro: Terumo Capiox SX25RX and Dideco D734 (SX/D734),Terumo Capiox RX25R and AF125 (RX/AF125), Terumo FX25R (FX), Sorin Synthesis with 102 microm reservoir filter (SYN102), and Sorin Synthesis with 40 microm reservoir filter (SYN40). GME handling was studied by introducing air into the venous return at 100 mL/min for 60 seconds under two flow/ pressure combinations: 3.5 L/min, 150 mmHg and 5 L/min, 200 mmHg. Emboli were measured at three positions in the circuit using the Emboli Detection and Classification (EDAC) Quantifier and analyzed with the General Linear Model. All circuits significantly reduced GME. The SX/D734 and SYN40 circuits were most efficient in GME removal whilst the SYN102 handled embolic load (count and volume) least efficiently (p circuits (p circuits (p circuits to handle GME. Venous reservoir design influenced the overall GME handling ability. GME removal was less efficient at higher flow and pressure, and for smaller sized emboli. The clinical significance of reducing GME requires further investigation.

  18. The U-line line balancing problem

    Miltenburg, G.J.; Wijngaard, J.

    1994-01-01

    The traditional line balancing (LB) problem considers a production line in which stations are arranged consecutively in a line. A balance is determined by grouping tasks into stations while moving forward (or backward) through a precedence network. Recently many production lines are being arranged

  19. A DETAILED STUDY OF NON-THERMAL X-RAY PROPERTIES AND INTERSTELLAR GAS TOWARD THE γ-RAY SUPERNOVA REMNANT RX J1713.7–3946

    Sano, H.; Fukuda, T.; Yoshiike, S.; Sato, J.; Horachi, H.; Kuwahara, T.; Torii, K.; Hayakawa, T.; Matsumoto, H.; Inutsuka, S.; Yamamoto, H.; Tachihara, K. [Department of Physics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); Tanaka, T. [Department of Physics, Kyoto University, Kitashirakawa-oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Inoue, T.; Kawamura, A.; Okuda, T.; Mizuno, N. [National Astronomical Observatory of Japan, Mitaka 181-8588 (Japan); Yamazaki, R. [Department of Physics and Mathematics, Aoyama Gakuin University, Fuchinobe, Chuou-ku, Sagamihara 252-5258 (Japan); Onishi, T. [Department of Astrophysics, Graduate School of Science, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai 599-8531 (Japan); Mizuno, A., E-mail: sano@a.phys.nagoya-u.ac.jp [Solar-Terrestrial Environment Laboratory, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); and others

    2015-02-01

    We have carried out a spectral analysis of the Suzaku X-ray data in the 0.4-12 keV range toward the shell-type very high-energy γ-ray supernova remnant (SNR) RX J1713.7–3946. The aims of this analysis are to estimate detailed X-rays spectral properties at a high angular resolution up to 2 arcmin and to compare them with the interstellar gas. The X-ray spectrum is non-thermal and used to calculate absorbing column density, photon index, and absorption-corrected X-ray flux. The photon index varies significantly from 2.1 to 2.9. It is shown that the X-ray intensity is well correlated with the photon index, especially in the west region, with a correlation coefficient of 0.81. The X-ray intensity tends to increase with the averaged interstellar gas density while the dispersion is relatively large. The hardest spectra, with photon indexes of less than 2.4, are found outside of the central 10 arcmin of the SNR, from the north to the southeast (∼430 arcmin{sup 2}) and from the southwest to the northwest (∼150 arcmin{sup 2}). The former region shows low interstellar gas density, while the latter shows high interstellar gas density. We present a discussion of possible scenarios that explain the distribution of the photon index and its relationship with the interstellar gas.

  20. CONSTRAINING THE SPIN-DOWN OF THE NEARBY ISOLATED NEUTRON STAR RX J0806.4-4123, AND IMPLICATIONS FOR THE POPULATION OF NEARBY NEUTRON STARS

    Kaplan, D. L.; Van Kerkwijk, M. H.

    2009-01-01

    The nearby isolated neutron stars (INSs) are a group of seven relatively slowly rotating neutron stars that show thermal X-ray spectra, most with broad absorption features. They are interesting both because they may allow one to determine fundamental neutron-star properties by modeling their spectra, and because they appear to be a large fraction of the overall neutron-star population. Here, we describe a series of XMM -Newton observations of the nearby INS RX J0806.4-4123, taken as part of larger program of timing studies. From these, we limit the spin-down rate to ν-dot=(-4.3±2.3)x10 -16 Hz s -1 . This constrains the dipole magnetic field to be 13 G at 2σ, significantly less than the field of ∼10 14 G implied by simple models for the X-ray absorption found at 0.45 keV. We confirm that the spectrum is thermal and stable (to within a few percent), but find that the 0.45 keV absorption feature is broader and more complex than previously thought. Considering the population of INSs, we find that magnetic field decay from an initial field of ∼ 14 G accounts most naturally for their timing and spectral properties, both qualitatively and in the context of the models for field decay of Pons and collaborators.

  1. Detection of X-ray flares from AX J1714.1-3912, the unidentified source near RX J1713.7-3946

    Miceli, Marco; Bamba, Aya

    2018-04-01

    Context. Molecular clouds are predicted to emit nonthermal X-rays when they are close to particle-accelerating supernova remnants (SNRs), and the hard X-ray source AX J1714.1-3912, near the SNR RX J1713.7-3946, has long been considered a candidate for diffuse nonthermal emission associated with cosmic rays diffusing from the remnant to a closeby molecular cloud. Aim. We aim at ascertaining the nature of this source by analyzing two dedicated X-ray observations performed with Suzaku and Chandra. Methods: We extracted images from the data in various energy bands, spectra, and light curves and studied the long-term evolution of the X-ray emission on the basis of the 4.5 yr time separation between the two observations. Results: We found that there is no diffuse emission associated with AX J1714.1-3912, which is instead the point-like source CXOU J171343.9-391205. We discovered rapid time variability (timescale 103 s), together with a high intrinsic absorption and a hard nonthermal spectrum (power law with photon index Γ 1.4). We also found that the X-ray flux of the source drops down by 1-2 orders of magnitude on a timescale of a few years. Conclusions: Our results suggest a possible association between AX J1714.1-3912 and a previously unknown supergiant fast X-ray transient, although further follow-up observations are necessary to prove this association definitively.

  2. The Effectiveness of Pharmacist Interventions on Cardiovascular Risk in Adult Patients with Type 2 Diabetes: The Multicentre Randomized Controlled RxEACH Trial.

    Al Hamarneh, Yazid N; Hemmelgarn, Brenda R; Hassan, Imran; Jones, Charlotte A; Tsuyuki, Ross T

    2017-12-01

    Cardiovascular disease (CVD) is the leading cause of death among patients with diabetes. Management and control of CV risk factors in those with diabetes are generally poor. Pharmacists are frontline primary healthcare providers who see patients with chronic diseases frequently. As such, they are in a prime position to systematically identify patients with diabetes, assess their CV risk and assist in their disease management and preventive measures. to evaluate the effect of pharmacist case finding and intervention program on estimated CV risk in patients with diabetes. Sub-group analysis of a randomized controlled trial (RxEACH). Patients were randomized to receive intervention or usual care for 3 months. Those who were randomized to the intervention group received a Medication Therapy Management consultation which included patient assessment, laboratory assessment, individualized CV risk assessment. Treatment regimen adjustment, as needed, in order to meet treatment targets. Estimated CV risk was reduced from 26.9 +/- 21% to 26.5 +/- 21.3% in the control group and from 25.8 +/- 19.4% to 20.1 +/- 17.2% in the intervention group over the 3-month follow up period (an absolute reduction of 5.38; 95% confidence interval (CI) 4.24 to 6.52; p <0.001). Community pharmacy-based case finding and intervention program reduced the risk for major CV events by 21% when compared to usual practice. This represents a promising approach to help tackle the major public health problem of diabetes in Canada. Copyright © 2017 Diabetes Canada. Published by Elsevier Inc. All rights reserved.

  3. Improving patient safety and efficiency of medication reconciliation through the development and adoption of a computer-assisted tool with automated electronic integration of population-based community drug data: the RightRx project.

    Tamblyn, Robyn; Winslade, Nancy; Lee, Todd C; Motulsky, Aude; Meguerditchian, Ari; Bustillo, Melissa; Elsayed, Sarah; Buckeridge, David L; Couture, Isabelle; Qian, Christina J; Moraga, Teresa; Huang, Allen

    2018-05-01

    Many countries require hospitals to implement medication reconciliation for accreditation, but the process is resource-intensive, thus adherence is poor. We report on the impact of prepopulating and aligning community and hospital drug lists with data from population-based and hospital-based drug information systems to reduce workload and enhance adoption and use of an e-medication reconciliation application, RightRx. The prototype e-medical reconciliation web-based software was developed for a cluster-randomized trial at the McGill University Health Centre. User-centered design and agile development processes were used to develop features intended to enhance adoption, safety, and efficiency. RightRx was implemented in medical and surgical wards, with support and training provided by unit champions and field staff. The time spent per professional using RightRx was measured, as well as the medication reconciliation completion rates in the intervention and control units during the first 20 months of the trial. Users identified required modifications to the application, including the need for dose-based prescribing, the role of the discharge physician in prescribing community-based medication, and access to the rationale for medication decisions made during hospitalization. In the intervention units, both physicians and pharmacists were involved in discharge reconciliation, for 96.1% and 71.9% of patients, respectively. Medication reconciliation was completed for 80.7% (surgery) to 96.0% (medicine) of patients in the intervention units, and 0.7% (surgery) to 82.7% of patients in the control units. The odds of completing medication reconciliation were 9 times greater in the intervention compared to control units (odds ratio: 9.0, 95% confidence interval, 7.4-10.9, P < .0001) after adjusting for differences in patient characteristics. High rates of medication reconciliation completion were achieved with automated prepopulation and alignment of community and hospital

  4. H.E.S.S. observations of RX J1713.7-3946 with improved angular and spectral resolution: Evidence for gamma-ray emission extending beyond the X-ray emitting shell

    H. E. S. S. Collaboration; Abdalla, H.; Abramowski, A.; Aharonian, F.; Benkhali, F. Ait; Akhperjanian, A. G.; Andersson, T.; Angüner, E. O.; Arrieta, M.; Aubert, P.; Backes, M.; Balzer, A.; Barnard, M.; Becherini, Y.; Tjus, J. Becker; Berge, D.; Bernhard, S.; Bernlöhr, K.; Blackwell, R.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Bregeon, J.; Brun, F.; Brun, P.; Bryan, M.; Bulik, T.; Capasso, M.; Carr, J.; Casanova, S.; Cerruti, M.; Chakraborty, N.; Chalme-Calvet, R.; Chaves, R. C. G.; Chen, A.; Chevalier, J.; Chrétien, M.; Colafrancesco, S.; Cologna, G.; Condon, B.; Conrad, J.; Cui, Y.; Davids, I. D.; Decock, J.; Degrange, B.; Deil, C.; Devin, J.; deWilt, P.; Dirson, L.; Djannati-Ataï, A.; Domainko, W.; Donath, A.; Drury, L. O.'C.; Dubus, G.; Dutson, K.; Dyks, J.; Edwards, T.; Egberts, K.; Eger, P.; Ernenwein, J.-P.; Eschbach, S.; Farnier, C.; Fegan, S.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Fukuyama, T.; Funk, S.; Füßling, M.; Gabici, S.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Gottschall, D.; Goyal, A.; Grondin, M.-H.; Hadasch, D.; Hahn, J.; Haupt, M.; Hawkes, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hinton, J. A.; Hofmann, W.; Hoischen, C.; Holler, M.; Horns, D.; Ivascenko, A.; Jacholkowska, A.; Jamrozy, M.; Janiak, M.; Jankowsky, D.; Jankowsky, F.; Jingo, M.; Jogler, T.; Jouvin, L.; Jung-Richardt, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kerszberg, D.; Khélifi, B.; Kieffer, M.; King, J.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Kraus, M.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lau, J.; Lees, J.-P.; Lefaucheur, J.; Lefranc, V.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Leser, E.; Lohse, T.; Lorentz, M.; Liu, R.; López-Coto, R.; Lypova, I.; Marandon, V.; Marcowith, A.; Mariaud, C.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; Meintjes, P. J.; Meyer, M.; Mitchell, A. M. W.; Moderski, R.; Mohamed, M.; Mohrmann, L.; Morå, K.; Moulin, E.; Murach, T.; Naurois, M. de; Niederwanger, F.; Niemiec, J.; Oakes, L.; O'Brien, P.; Odaka, H.; Öttl, S.; Ohm, S.; Ostrowski, M.; Oya, I.; Padovani, M.; Panter, M.; Parsons, R. D.; Pekeur, N. W.; Pelletier, G.; Perennes, C.; Petrucci, P.-O.; Peyaud, B.; Piel, Q.; Pita, S.; Poon, H.; Prokhorov, D.; Prokoph, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Reimer, A.; Reimer, O.; Renaud, M.; los Reyes, R. de; Rieger, F.; Romoli, C.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Salek, D.; Sanchez, D. A.; Santangelo, A.; Sasaki, M.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwemmer, S.; Settimo, M.; Seyffert, A. S.; Shafi, N.; Shilon, I.; Simoni, R.; Sol, H.; Spanier, F.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Takahashi, T.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tibaldo, L.; Tiziani, D.; Tluczykont, M.; Trichard, C.; Tuffs, R.; Uchiyama, Y.; van der Walt, D. J.; Eldik, C. van; Rensburg, C. van; Soelen, B. van; Vasileiadis, G.; Veh, J.; Venter, C.; Viana, A.; Vincent, P.; Vink, J.; Voisin, F.; Völk, H. J.; Volpe, F.; Vuillaume, T.; Wadiasingh, Z.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zaborov, D.; Zacharias, M.; Zdziarski, A. A.; Zech, A.; Zefi, F.; Ziegler, A.; Żywucka, N.

    2018-04-01

    Supernova remnants exhibit shock fronts (shells) that can accelerate charged particles up to very high energies. In the past decade, measurements of a handful of shell-type supernova remnants in very high-energy gamma rays have provided unique insights into the acceleration process. Among those objects, RX J1713.7-3946 (also known as G347.3-0.5) has the largest surface brightness, allowing us in the past to perform the most comprehensive study of morphology and spatially resolved spectra of any such very high-energy gamma-ray source. Here we present extensive new H.E.S.S. measurements of RX J1713.7-3946, almost doubling the observation time compared to our previous publication. Combined with new improved analysis tools, the previous sensitivity is more than doubled. The H.E.S.S. angular resolution of 0.048° (0.036° above 2 TeV) is unprecedented in gamma-ray astronomy and probes physical scales of 0.8 (0.6) parsec at the remnant's location. The new H.E.S.S. image of RX J1713.7-3946 allows us to reveal clear morphological differences between X-rays and gamma rays. In particular, for the outer edge of the brightest shell region, we find the first ever indication for particles in the process of leaving the acceleration shock region. By studying the broadband energy spectrum, we furthermore extract properties of the parent particle populations, providing new input to the discussion of the leptonic or hadronic nature of the gamma-ray emission mechanism. All images (FITS files) are available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/612/A6

  5. Molecular epidemiology and virulence of Escherichia coli O16:H5-ST131: comparison with H30 and H30-Rx subclones of O25b:H4-ST131.

    Dahbi, Ghizlane; Mora, Azucena; Mamani, Rosalia; López, Cecilia; Alonso, María Pilar; Marzoa, Juan; Blanco, Miguel; Herrera, Alexandra; Viso, Susana; García-Garrote, Fernando; Tchesnokova, Veronika; Billig, Mariya; de la Cruz, Fernando; de Toro, María; González-López, Juan José; Prats, Guillermo; Chaves, Fernando; Martínez-Martínez, Luis; López-Cerezo, Lorena; Denamur, Erick; Blanco, Jorge

    2014-11-01

    The present study was carried out to evaluate the prevalence of the clonal subgroup O16:H5-ST131 and the H30 and H30-Rx subclones among E. coli isolates causing extraintestinal infections and to know their virulence potential. The ST131 clonal group accounted for 490 (16%) of the 2995 isolates obtained from clinical samples in five Spanish hospitals during the study period (2005-2012). Among those 490 ST131 isolates, 456 belonged to serotype O25b:H4, 27 to O16:H5 and seven were O-non-typeable:H4 (ONT:H4). All 27 O16:H5 isolates showed fimH41, whereas fimH30 and fimH22 alleles were the most frequently detected among O25b:H4 isolates. The majority (381/490; 78%) of ST131 isolates belonged to H30 subclone, and 302 of 381 (79%) H30 isolates belonged to the H30-Rx subclone. Of the 27 O16:H5 isolates, 48% produced CTX-M-14; however, none produced CTX-M-15. In contrast, 46% of O25b:H4 isolates produced CTX-M-15 while only 2% produced CTX-M-14. More than a half of the O16:H5 isolates (56%) showed the ExPEC status which was significantly more prevalent within O25b:H4 isolates (81%) (P<0.01), especially among H30-Rx (97%) isolates. In the present study, a modified virotype scheme was applied within which approximately half (52%) of the O16:H5 isolates showed the C1 specific virotype. Despite their low virulence-gene score (mean of virulence genes 6.4 versus 8.5 in O25b:H4 isolates), six out of the 10 O16:H5 isolates assayed showed high virulence in the mouse model of sepsis (killed 90-100% of mice challenged). Furthermore, four O16:H5 isolates of virotypes A and C1, carrying K2 variant of group II capsule, showed lethality at 24h. Thus, certain O16:H5 fimH41 isolates show a similar in vivo virulence to that reported with the highly virulent O25b:H4 H30-Rx isolates (Mora et al., PLOS ONE 2014, e87025), supporting their potential virulence for humans. Copyright © 2014 Elsevier GmbH. All rights reserved.

  6. Cable line engineering

    Jang, Hak Sin; Kim, Sin Yeong

    1998-02-01

    This book is about cable line engineering. It is comprised of nine chapters, which deals with summary of cable communication such as way, process of cable communication and optical communication, Line constant of transmission on primary constant, reflection and crosstalk, communication cable line of types like flat cable, coaxial cable and loaded cable, Install of communication line with types and facility of aerial line, construction method of communication line facility, Measurement of communication line, Carrier communication of summary, PCM communication with Introduction, regeneration relay system sampling and quantization and Electric communication service and general information network with mobile communication technique and satellite communication system.

  7. Application of the Cavity theory in the calibration of the powder TLD-100 for energies of 60 Co, 137 Cs, 192 Ir and RX 50, 250 k Vp

    Loaiza C, S.P.; Alvarez R, J.T.

    2006-01-01

    A powder lot TLD-100 (LiF:Mg,Ti) in absorbed dose terms in water D w for the following radiation sources: 60 Co, 137 Cs and RX 50 and 250 k Vp is calibrated; to continuation is made a lineal interpolation of the TLD response in function of the effective energy of the sources to calibrate a source of 192 Ir. The calibration of those fields in D w are carried out with aid of the Bragg-Gray cavity theory, the one which finds implicit in the following protocols: IAEA-TRS 398 for the 60 Co and the AAPM TG61 for X Rays of 50 and 250 k Vp. Additionally the AAPM protocol TG43 to determine the D w in function of the kerma intensity S k in the case of the 137 Cs is used. The calibration curves for the response of the TLD-100 R TLD vs D w , corresponding to each one of the sources already mentioned are constructed. The R TLD vs D w by least heavy square by means of a second order polynomial that corrects the supralineality of the response is adjusted. The curves are validated by lack of LOF adjustment and by the Anderson Darling normality test. Later the factors of sensitivity (F s ) for the sources of 192 Ir: Micro Selectron and Vari Source are interpolated, used respectively in the A and B hospitals for treatments of brachytherapy of high dose rate (HDR), the expanded uncertainties associated to the D w and F s are also determined. Finally, an acrylic phantom and a couple of capsules are already sent to the hospitals mentioned, to verify a nominal D w of 2 Gy, in a case an underestimate in 5.5% in the imparted D w and in other an overestimation in a range of -1.5 to -8.0% was obtained. The obtained results in this work establish the bases for the development of a national dosimetric quality control program for brachytherapy of HDR with sources of 192 Ir. (Author)

  8. Quartzo magmático e hidrotermal do depósito de ouro São Jorge, Província Aurífera do Tapajós, Pará: petrografia, microscopia eletrônica de varredura-catodoluminescência e implicações metalogenéticas

    Aldemir de Melo Sotero

    Full Text Available Estudos em cristais de quartzo presentes nas associações minerais para a área do depósito de ouro São Jorge, Província Aurífera do Tapajós, sudoeste do estado do Pará, identificaram quatro tipos morfológico-texturais (Qz1, Qz2, Qz3 e Qz4 com base em imagens de microscopia eletrônica de varredura-catodoluminescência. Nas rochas mais preservadas do Granito São Jorge Jovem, ricas em anfibólio e biotita (associações 1 e 2, dominam cristais anédricos de quartzo magmático com luminescência alta a moderada (Qz1. Nas rochas parcialmente alteradas (associações 2 e 3, fluidos pós-magmáticos a hidrotermais afetaram o granito e percolaram fraturas do Qz1 e cristalizaram Qz2 não luminescente (escuro. Nas rochas mais intensamente alteradas (associação 4, sucessivos processos de alteração, dissolução e recristalização deram origem a cristais de quartzo zonados subédricos (Qz3 e euédricos (Qz4. Imagens por elétrons retroespalhados e análises semiquantitativas por espectroscopia por dispersão de energia identificaram duas gerações de ouro: Au1, enriquecido em Ag (4,3 a 23,7% e associado a cristais de pirita; Au2, enriquecido em Te (1,1 a 17,2% e incluso ou associado ao Qz4. O estudo de microscopia eletrônica de varredura-catodoluminescência forneceu informações importantes que foram preservadas na estrutura do quartzo. A evolução morfológico-textural desse mineral em diferentes estágios evidencia a ação gradativa do hidrotermalismo nas rochas e nas associações minerais do depósito São Jorge. A mineralização aurífera do depósito foi caracterizada quimicamente (espectroscopia por dispersão de energia e parageneticamente (pirita, esfalerita e Qz4, podendo ser dividida em gerações ou eventos mineralizantes distintos. A eficiência da metodologia utilizada neste estudo foi comprovada, permitindo sua aplicação em estudos de outros depósitos hidrotermais.

  9. VT Electric Transmission Line Corridors - corridor lines

    Vermont Center for Geographic Information — (Link to Metadata) The ELTRN layer depicts electric transmission line corridors in Vermont. Various methods have been used to digitize features. The data layer...

  10. Hypersurfaces satisfying Lrx= Rx Lrx= Rx Lrx= Rx in sphere Sn Sn ...

    Author Affiliations. Biaogui Yang1 Ximin Liu2. School of Mathematics and Computer Science, Fujian Normal University, Fuzhou 350108, People's Republic of China; Department of Mathematics, South China University of Technology, Gangzhou 510641, People's Republic of China ...

  11. Homotopic Polygonal Line Simplification

    Deleuran, Lasse Kosetski

    This thesis presents three contributions to the area of polygonal line simplification, or simply line simplification. A polygonal path, or simply a path is a list of points with line segments between the points. A path can be simplified by morphing it in order to minimize some objective function...

  12. Elevación diafragmática con colapso de la aurícula derecha y síntomas de falla cardíaca: reporte de un caso Diaphragmatic elevation with collapse of the right atrium and symptoms of heart failure: a case report

    Juan C Díaz

    2013-02-01

    Full Text Available La elevación diafragmática es una entidad caracterizada por la alteración en la fuerza contráctil de las fibras musculares del diafragma, que conlleva prolapso de las estructuras abdominales hacia la cavidad torácica. En la mayoría de los casos, los síntomas se presentan por la compresión del parénquima pulmonar subyacente; la compresión de estructuras cardíacas es menos frecuente. Se reporta el caso de una paciente que presentó signos y síntomas compatibles con falla cardíaca derecha y en quien los diferentes estudios demostraron una elevación diafragmática con colapso de la aurícula derecha como causa de su sintomatología.Diaphragmatic elevation is a disorder characterized by impaired contractile force of the muscle fibers of the diaphragm, which results in prolapse of abdominal structures into the chest cavity. In most cases, symptoms occur by the underlying lung parenchyma compression. The compression of cardiac structures is less frequent. We report the case of a female patient who developed signs and symptoms consistent with right heart failure and in whom several studies showed a diaphragmatic elevation with collapse of the right atrium as cause of her symptomatology.

  13. Non-thermal X-rays and interstellar gas toward the γ-ray supernova remnant RX J1713.7–3946: evidence for X-ray enhancement around CO and H I clumps

    Sano, H.; Torii, K.; Fukuda, T.; Yoshiike, S.; Sato, J.; Horachi, H.; Kuwahara, T.; Hayakawa, T.; Matsumoto, H.; Inutsuka, S.; Kawamura, A.; Tachihara, K.; Yamamoto, H.; Okuda, T.; Mizuno, N.; Onishi, T. [Department of Physics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); Tanaka, T. [Department of Physics, Kyoto University, Kitashirakawa-oiwake-cho, Sakyo-ku, Kyoto 606-8502 (Japan); Inoue, T.; Yamazaki, R. [Department of Physics and Mathematics, Aoyama Gakuin University, Fuchinobe, Chuou-ku, Sagamihara 252-5258 (Japan); Mizuno, A., E-mail: sano@a.phys.nagoya-u.ac.jp [Solar-Terrestrial Environment Laboratory, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); and others

    2013-11-20

    RX J1713.7–3946 is the most remarkable very high energy γ-ray supernova remnant that emits synchrotron X-rays without thermal features. We made a comparative study of CO, H I, and X-rays in order to better understand the relationship between the X-rays, and the molecular and atomic gas. The results indicate that the X-rays are enhanced around the CO and H I clumps on a pc scale, but are decreased inside the clumps on a 0.1 pc scale. Magnetohydrodynamic numerical simulations of the shock interaction with molecular and atomic gas indicate that the interaction between the shock waves and the clumps excite turbulence, which amplifies the magnetic field around the clumps. We suggest that the amplified magnetic field around the CO and H I clumps enhances the synchrotron X-rays and possibly the acceleration of cosmic-ray electrons.

  14. Directed line liquids

    Kamien, R.D.

    1992-01-01

    This thesis is devoted to the study of ensembles of dense directed lines. These lines are principally to be thought of as polymers, though they also have the morphology of flux lines in high temperature superconductors, strings of colloidal spheres in electrorheological fluids and the world lines of quantum mechanical bosons. The authors discuss how directed polymer melts, string-like formations in electrorheological and ferro-fluids, flux lines in high temperature superconductors and the world lines of quantum mechanical bosons all share similar descriptions. They study a continuous transition in all of these systems, and then study the critical mixing properties of binary mixtures of directed polymers through the renormalization group. They predict the exponents for a directed polymer blend consolute point and a novel two-phase superfluid liquid-gas critical point

  15. Series Transmission Line Transformer

    Buckles, Robert A.; Booth, Rex; Yen, Boris T.

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  16. Covariant electromagnetic field lines

    Hadad, Y.; Cohen, E.; Kaminer, I.; Elitzur, A. C.

    2017-08-01

    Faraday introduced electric field lines as a powerful tool for understanding the electric force, and these field lines are still used today in classrooms and textbooks teaching the basics of electromagnetism within the electrostatic limit. However, despite attempts at generalizing this concept beyond the electrostatic limit, such a fully relativistic field line theory still appears to be missing. In this work, we propose such a theory and define covariant electromagnetic field lines that naturally extend electric field lines to relativistic systems and general electromagnetic fields. We derive a closed-form formula for the field lines curvature in the vicinity of a charge, and show that it is related to the world line of the charge. This demonstrates how the kinematics of a charge can be derived from the geometry of the electromagnetic field lines. Such a theory may also provide new tools in modeling and analyzing electromagnetic phenomena, and may entail new insights regarding long-standing problems such as radiation-reaction and self-force. In particular, the electromagnetic field lines curvature has the attractive property of being non-singular everywhere, thus eliminating all self-field singularities without using renormalization techniques.

  17. Minnesota County Boundaries - lines

    Minnesota Department of Natural Resources — Minnesota county boundaries derived from a combination of 1:24,000 scale PLS lines, 1:100,000 scale TIGER, 1:100,000 scale DLG, and 1:24,000 scale hydrography lines....

  18. Database of emission lines

    Binette, L.; Ortiz, P.; Joguet, B.; Rola, C.

    1998-11-01

    A widely accessible data bank (available through Netscape) and consiting of all (or most) of the emission lines reported in the litterature is being built. It will comprise objects as diverse as HII regions, PN, AGN, HHO. One of its use will be to define/refine existing diagnostic emission line diagrams.

  19. Wood pole overhead lines

    Wareing, Brian

    2005-01-01

    This new book concentrates on the mechanical aspects of distribution wood pole lines, including live line working, environmental influences, climate change and international standards. Other topics include statutory requirements, safety, profiling, traditional and probabilistic design, weather loads, bare and covered conductors, different types of overhead systems, conductor choice, construction and maintenance. A section has also been devoted to the topic of lightning, which is one of the major sources of faults on overhead lines. The book focuses on the effects of this problem and the strate

  20. Veterans Crisis Line

    Department of Veterans Affairs — The caring responders at the Veterans Crisis Line are specially trained and experienced in helping Veterans of all ages and circumstances. Some of the responders are...

  1. Product line design

    Anderson, S. P.; Celik, Levent

    2015-01-01

    Roč. 157, May (2015), s. 517-526 ISSN 0022-0531 Institutional support: RVO:67985998 Keywords : product line design * product differentiation * second-degree price discrimination Subject RIV: AH - Economics Impact factor: 1.097, year: 2015

  2. Kansas Electric Transmission Lines

    Kansas Data Access and Support Center — This data set is a digital representation of the EletcircTransmission lines for the State of Kansas as maintained by the Kansas Corporation Commission. Data is...

  3. Electric Power Transmission Lines

    Department of Homeland Security — Transmission Lines are the system of structures, wires, insulators and associated hardware that carry electric energy from one point to another in an electric power...

  4. SAF line powder operations

    Frederickson, J.R.; Horgos, R.M.

    1983-10-01

    An automated nuclear fuel fabrication line is being designed for installation in the Fuels and Materials Examination Facility (FMEF) near Richland, Washington. The fabrication line will consist of seven major process systems: Receiving and Powder Preparation; Powder Conditioning; Pressing and Boat Loading; Debinding, Sintering, and Property Adjustment; Boat Transport; Pellet Inspection and Finishing; and Pin Operations. Fuel powder processing through pellet pressing will be discussed in this paper

  5. Capital Improvements Business Line

    2012-08-08

    NAVFAC Southwest Dan Waid Program & Business Mgmt NAVFAC SW Capital Improvements Business Line NAVFAC SW 8 August 2012 1 Report...REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Capital Improvements Business Line 5a. CONTRACT NUMBER 5b. GRANT...AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES Presented at the 2012 Navy Gold Coast Small Business

  6. Nasca Lines, Peru

    2001-01-01

    The Nasca Lines are located in the Pampa region of Peru, the desolate plain of the Peruvian coast 400 km south of Lima. The Lines were first spotted when commercial airlines began flying across the Peruvian desert in the 1920's. Passengers reported seeing 'primitive landing strips' on the ground below. The Lines were made by removing the iron-oxide coated pebbles which cover the surface of the desert. When the gravel is removed, they contrast with the light color underneath. In this way the lines were drawn as furrows of a lighter color. On the pampa, south of the Nasca Lines, archaeologists have now uncovered the lost city of the line-builders, Cahuachi. It was built nearly two thousand years ago and was mysteriously abandoned 500 years later. This ASTER sub-image covers an area of 14 x 18 km, was acquired on December 22, 2000, and is located at 14.7 degrees south latitude and 75.1 degrees west longitude. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  7. Transmission line capital costs

    Hughes, K.R.; Brown, D.R.

    1995-05-01

    The displacement or deferral of conventional AC transmission line installation is a key benefit associated with several technologies being developed with the support of the U.S. Department of Energy's Office of Energy Management (OEM). Previous benefits assessments conducted within OEM have been based on significantly different assumptions for the average cost per mile of AC transmission line. In response to this uncertainty, an investigation of transmission line capital cost data was initiated. The objective of this study was to develop a database for preparing preliminary estimates of transmission line costs. An extensive search of potential data sources identified databases maintained by the Bonneville Power Administration (BPA) and the Western Area Power Administration (WAPA) as superior sources of transmission line cost data. The BPA and WAPA data were adjusted to a common basis and combined together. The composite database covers voltage levels from 13.8 to 765 W, with cost estimates for a given voltage level varying depending on conductor size, tower material type, tower frame type, and number of circuits. Reported transmission line costs vary significantly, even for a given voltage level. This can usually be explained by variation in the design factors noted above and variation in environmental and land (right-of-way) costs, which are extremely site-specific. Cost estimates prepared from the composite database were compared to cost data collected by the Federal Energy Regulatory Commission (FERC) for investor-owned utilities from across the United States. The comparison was hampered because the only design specifications included with the FERC data were voltage level and line length. Working within this limitation, the FERC data were not found to differ significantly from the composite database. Therefore, the composite database was judged to be a reasonable proxy for estimating national average costs

  8. Along the line

    Dinesen, Cort Ross

    2011-01-01

    Embarking on a work of art constitutes a reduction of information – because we grasp the diversity and plurality of the manifestations we encounter by abstracting them and transforming them into manageable concepts; as we do when we draw contour lines on the landscape – they are imaginary...... and invisible but an abstraction essential for noting a difference or marking a place on a map. In the same way, a stroke in a sketch or a line in the sand is a manifestation of our ability to draw a boundary that both includes and excludes information. Where the line makes the birth of an idea visible......, it expresses through movement our tendency to mark a difference by drawing attention to and enclosing a whole series of relations that confront our preconceived notions. It is in the process of transformation in which we reduce the complexity of how we work, and rethink our ideas anew by refining the very same...

  9. Spectral Line Shapes. Proceedings

    Zoppi, M.; Ulivi, L.

    1997-01-01

    These proceedings represent papers presented at the 13th International Conference on Spectral Line Shapes which was held in Firenze,Italy from June 16-21, 1996. The topics covered a wide range of subjects emphasizing the physical processes associated with the formation of line profiles: high and low density plasma; atoms and molecules in strong laser fields, Dopple-free and ultra-fine spectroscopy; the line shapes generated by the interaction of neutrals, atoms and molecules, where the relavant quantities are single particle properties, and the interaction-induced spectroscopy. There were 131 papers presented at the conference, out of these, 6 have been abstracted for the Energy Science and Technology database

  10. Stokes line width

    Nikiskov, A.I.; Ritus, V.I.

    1993-01-01

    The concept of Stokes line width is introduced for the asymptotic expansions of functions near an essential singularity. Explicit expressions are found for functions (switching functions) that switch on the exponentially small terms for the Dawson integral, Airy function, and the gamma function. A different, more natural representation of a function, not associated with expansion in an asymptotic series, in the form of dominant and recessive terms is obtained by a special division of the contour integral which represents the function into contributions of higher and lower saddle points. This division leads to a narrower, natural Stokes line width and a switching function of an argument that depends on the topology of the lines of steepest descent from the saddle point

  11. VT Digital Line Graph Railroads

    Vermont Center for Geographic Information — (Link to Metadata) This datalayer is comprised of major railroad lines for the state of Vermont. These railroad lines line up well along quadrangle boundaries, but...

  12. Sprayed concrete linings

    Hindle, D.

    1999-12-01

    Sprayed concrete, or shotcrete, was invented in the 1920s for preserving dinosaur skeletons and was used underground initially in coalmines for the preservation and fine proofing of timber supports. Its use as a support lining in rock tunnelling was developed in the 1950s and 60s. The article surveys equipment available from major manufacturers and suppliers of concrete spraying equipment (Aliva, Cifa, GIA, Industri, Ingersoll Rand, etc.), specialist cement and additive manufacturers (Castle, Cement, Moria Carbotech). manufacturers of lattice girders and fibre reinforcement, and manufacturers of instrumentation for tunnel linings. 5 tabs., 9 photos.

  13. Pr:Ca1-xRxF2+x (R=Y or Gd) crystals: Modulated blue, orange and red emission spectra with the proportion of R3+ ions

    Yu, Hao; Qian, Xiaobo; Guo, Linyang; Jiang, Dapeng; Wu, Qinghui; Tang, Fei; Su, Liangbi; Ju, Qiangwen; Wang, Jingya; Xu, Jun

    2018-04-01

    The spectroscopic properties of 0.6at.%:Pr:Ca1-xRxF2+x (R = Y, Gd; x = 0,0.006, 0.012, 0.03, 0.06) crystals were investigated and compared. The XRD tests were conducted and the cell dimensions of the crystals were calculated. Room temperature absorption spectra have been registered and analyzed. The emission spectra and decay curves of the crystals were obtained at room temperature. Increasing the proportion of the lattice regulators of Y3+ or Gd3+ ions could significantly enhance the luminescence intensity of all visible emission bands with different ratios. Particularly, the emission intensity ratio of orange to red increased from 0.15 to 1.9 in Pr:Ca1-xYxF2+x crystals and to 1.02 in Pr:Ca1-xGdxF2+x crystals, respectively. Furthermore, Pr:Ca1-xGdxF2+x crystals have substantially strong emission at orange and red region of 580-660 nm, comparable with blue light at 482 nm. The quantum efficiency of the crystals increased rapidly with the increment of R3+ concentration, and finally tend to be 100%.

  14. Glue-paste linings

    Fuster-López, Laura; Andersen, Cecil Krarup; Bouillon, Nicolas

    2017-01-01

    Glue-paste linings of (Western) canvas paintings have been performed with a variety of materials throughout history and are present in a very significant amount of artworks in collections in Europe and elsewhere. Cereal flours and animal glues were usually the main ingredients because they were r...

  15. Product line design

    Anderson, S. P.; Celik, Levent

    2015-01-01

    Roč. 157, May (2015), s. 517-526 ISSN 0022-0531 R&D Projects: GA ČR(CZ) GA15-22540S Institutional support: PRVOUK-P23 Keywords : product line design * product differentiation * second-degree price discrimination Subject RIV: AH - Economics Impact factor: 1.097, year: 2015

  16. K-line photometry

    Henry, R.C.

    1979-01-01

    A brief review is given of more than a decade of work involving measurement of the strength of the K line of calcium in A-type stars. The effects of interstellar reddening are reexamined, and an improved estimate for the range in calcium abundance among field stars is obtained. (Auth.)

  17. SAF line pellet gaging

    Jedlovec, D.R.; Bowen, W.W.; Brown, R.L.

    1983-10-01

    Automated and remotely controlled pellet inspection operations will be utilized in the Secure Automated Fabrication (SAF) line. A prototypic pellet gage was designed and tested to verify conformance to the functions and requirements for measurement of diameter, surface flaws and weight-per-unit length

  18. Bike Map Lines

    Town of Chapel Hill, North Carolina — Chapel Hill Bike Map Lines from KMZ file.This data came from the wiki comment board for the public, not an “official map” showing the Town of Chapel Hill's plans or...

  19. Drawing the Line

    Holm, Isak Winkel

    2016-01-01

    of judgement that distinguishes between the inside and outside of a political community, between citizens and zombies. Second, the chapter focuses on the rhetorics applied to draw the line between rights-bearers and the rightless. ‘Prophetic’ speech, echoing the language of the Old Testament prophets, is vital...

  20. Developing Green Line Products

    Muñoz-Marin, Ana Maria; Lassen, Astrid Heidemann; Poulsen, Søren Bolvig

    2011-01-01

    This publication is based on the Master thesis “User-driven ecoinnovation process: Towards the implementation of the Green product line at JELD-WEN” written by Ana Maria Muñoz-Marin as her Graduation Project for the MSc. Global Innovation Management degree. The company-based experiment was carried...

  1. Magnetic field line Hamiltonian

    Boozer, A.H.

    1984-03-01

    The magnetic field line Hamiltonian and the associated canonical form for the magnetic field are important concepts both for understanding toroidal plasma physics and for practical calculations. A number of important properties of the canonical or Hamiltonian representation are derived and their importance is explained

  2. Mixed Lubricated Line Contacts

    Faraon, I.C.

    2005-01-01

    The present work deals with friction in mixed lubricated line contacts. Components in systems are becoming smaller and due to, for instance power transmitted, partial contact may occur. In industrial applications, friction between the moving contacting surfaces cannot be avoided, therefore it is

  3. Lined canvas paintings

    Krarup Andersen, Cecil

    2013-01-01

    at 50% RH but increased the stress level severely in dry conditions and offered no support to the painting at 70-80 % RH. This means that the traditional glue-paste lining techniques and the wax-resin technique in high RH seem to limit the advisable RH fluctuation in a cultural institution. Conversely...

  4. LEAR: antiproton extraction lines

    Photographic Service

    1992-01-01

    Antiprotons, decelerated in LEAR to a momentum of 100 MeV/c (kinetic energy of 5.3 MeV), were delivered to the experiments in an "Ultra-Slow Extraction", dispensing some 1E9 antiprotons over times counted in hours. Beam-splitters and a multitude of beam-lines allowed several users to be supplied simultaneously.

  5. Labelling subway lines

    Garrido, M.A.; Iturriaga, C.; Márquez, A.; Portillo, J.R.; Reyes, P.; Wolff, A.; Eades, P.; Takaoka, T.

    2001-01-01

    Graphical features on map, charts, diagrams and graph drawings usually must be annotated with text labels in order to convey their meaning. In this paper we focus on a problem that arises when labeling schematized maps, e.g. for subway networks. We present algorithms for labeling points on a line

  6. Subjective poverty line definitions

    J. Flik; B.M.S. van Praag (Bernard)

    1991-01-01

    textabstractIn this paper we will deal with definitions of subjective poverty lines. To measure a poverty threshold value in terms of household income, which separates the poor from the non-poor, we take into account the opinions of all people in society. Three subjective methods will be discussed

  7. Building with a Line

    Hubbert, Beth

    2011-01-01

    Architecture is a versatile, multifaceted area to study in the artroom with multiple age levels. It can easily stimulate a study of basic line, shape, and various other art elements and principles. It can then be extended into a more extensive study of architectural elements, styles, specific architects, architecture of different cultures, and…

  8. Biosynthesis: Reprogramming assembly lines

    Menon, Binuraj R. K.; Jenner, Matthew

    2018-03-01

    Rational engineering of biosynthetic assembly lines for production of new compounds is an attractive prospect, yet it presents many challenges. Learning from biology, some of the rules for expanding the chemical diversity of non-ribosomal peptides have been uncovered in two recent studies.

  9. Magnetic field line Hamiltonian

    Boozer, A.H.

    1985-02-01

    The basic properties of the Hamiltonian representation of magnetic fields in canonical form are reviewed. The theory of canonical magnetic perturbation theory is then developed and applied to the time evolution of a magnetic field embedded in a toroidal plasma. Finally, the extension of the energy principle to tearing modes, utilizing the magnetic field line Hamiltonian, is outlined

  10. Defining line replaceable units

    Parada Puig, J. E.; Basten, R. J I

    2015-01-01

    Defective capital assets may be quickly restored to their operational condition by replacing the item that has failed. The item that is replaced is called the Line Replaceable Unit (LRU), and the so-called LRU definition problem is the problem of deciding on which item to replace upon each type of

  11. Multiple Lines of Evidence

    Amidan, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Venzin, Alexander M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bramer, Lisa M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-06-03

    This paper discusses the process of identifying factors that influence the contamination level of a given decision area and then determining the likelihood that the area remains unacceptable. This process is referred to as lines of evidence. These lines of evidence then serve as inputs for the stratified compliance sampling (SCS) method, which requires a decision area to be divided into strata based upon contamination expectations. This is done in order to focus sampling efforts more within stratum where contamination is more likely and to use the domain knowledge about these likelihoods of the stratum remaining unacceptable to buy down the number of samples necessary, if possible. Two different building scenarios were considered as an example (see Table 3.1). SME expertise was elicited concerning four lines of evidence factors (see Table 3.2): 1) amount of contamination that was seen before decontamination, 2) post-decontamination air sampling information, 3) the applied decontaminant information, and 4) the surface material. Statistical experimental design and logistic regression modelling were used to help determine the likelihood that example stratum remained unacceptable for a given example scenario. The number of samples necessary for clearance was calculated by applying the SCS method to the example scenario, using the estimated likelihood of each stratum remaining unacceptable as was determined using the lines of evidence approach. The commonly used simple random sampling (SRS) method was also used to calculate the number of samples necessary for clearance for comparison purposes. The lines of evidence with SCS approach resulted in a 19% to 43% reduction in total number of samples necessary for clearance (see Table 3.6). The reduction depended upon the building scenario, as well as the level of percent clean criteria. A sensitivity analysis was also performed showing how changing the estimated likelihoods of stratum remaining unacceptable affect the number

  12. The last line effect explained

    Beller, M. (Moritz); Zaidman, A. (Andy); Karpov, A. (Andrey); R.A. Zwaan (Rolf)

    2017-01-01

    textabstractMicro-clones are tiny duplicated pieces of code; they typically comprise only few statements or lines. In this paper, we study the “Last Line Effect,” the phenomenon that the last line or statement in a micro-clone is much more likely to contain an error than the previous lines or

  13. The last line effect explained

    Beller, M.M.; Zaidman, A.E.; Karpov, Andrey; Zwaan, Rolf A.

    Micro-clones are tiny duplicated pieces of code; they typically comprise only few statements or lines. In this paper, we study the “Last Line Effect,” the phenomenon that the last line or statement in a micro-clone is much more likely to contain an error than the previous lines or statements. We do

  14. Contact Line Dynamics

    Kreiss, Gunilla; Holmgren, Hanna; Kronbichler, Martin; Ge, Anthony; Brant, Luca

    2017-11-01

    The conventional no-slip boundary condition leads to a non-integrable stress singularity at a moving contact line. This makes numerical simulations of two-phase flow challenging, especially when capillarity of the contact point is essential for the dynamics of the flow. We will describe a modeling methodology, which is suitable for numerical simulations, and present results from numerical computations. The methodology is based on combining a relation between the apparent contact angle and the contact line velocity, with the similarity solution for Stokes flow at a planar interface. The relation between angle and velocity can be determined by theoretical arguments, or from simulations using a more detailed model. In our approach we have used results from phase field simulations in a small domain, but using a molecular dynamics model should also be possible. In both cases more physics is included and the stress singularity is removed.

  15. Adaptive method of lines

    Saucez, Ph

    2001-01-01

    The general Method of Lines (MOL) procedure provides a flexible format for the solution of all the major classes of partial differential equations (PDEs) and is particularly well suited to evolutionary, nonlinear wave PDEs. Despite its utility, however, there are relatively few texts that explore it at a more advanced level and reflect the method''s current state of development.Written by distinguished researchers in the field, Adaptive Method of Lines reflects the diversity of techniques and applications related to the MOL. Most of its chapters focus on a particular application but also provide a discussion of underlying philosophy and technique. Particular attention is paid to the concept of both temporal and spatial adaptivity in solving time-dependent PDEs. Many important ideas and methods are introduced, including moving grids and grid refinement, static and dynamic gridding, the equidistribution principle and the concept of a monitor function, the minimization of a functional, and the moving finite elem...

  16. Limit lines for risk

    Cox, D.C.; Baybutt, P.

    1982-01-01

    Approaches to the regulation of risk from technological systems, such as nuclear power plants or chemical process plants, in which potential accidents may result in a broad range of adverse consequences must take into account several different aspects of risk. These include overall or average risk, accidents posing high relative risks, the rate at which accident probability decreases with increasing accident consequences, and the impact of high frequency, low consequence accidents. A hypothetical complementary cumulative distribution function (CCDF), with appropriately chosen parametric form, meets all these requirements. The Farmer limit line, by contrast, places limits on the risks due to individual accident sequences, and cannot adequately account for overall risk. This reduces its usefulness as a regulatory tool. In practice, the CCDF is used in the Canadian nuclear licensing process, while the Farmer limit line approach, supplemented by separate qualitative limits on overall risk, is employed in the United Kingdom

  17. Draw the Line!

    present proceedings from the UPGEM conference "Draw the Line!" in Copenhagen May 2008. The proceedings include contributions by UPGEM researchers, conference speeches by other researchers, politicians and gender equality officers in which they relate their work and research with the research done in UPGEM......Draw the Line! International Conference, Copenhagen 2008 Papers, proceedings and recommendations is the second publication of the international three year long project "Understanding Puzzles in the Gendered European Map" (UPGEM), which is financed by the European Commission. In this publication we....... The UPGEM research has previously been published in national reports from each of the partner countries (Denmark, Estonia, Finland, Italy and Poland). In these individual national reports of universities as workplaces for male and female researchers we discuss scientific cultures in physics embedded...

  18. SLIA beam line design

    Petillo, J.; Chernin, D.; Kostas, C.; Mondelli, A.

    1990-01-01

    The Spiral Line Induction Accelerator (SLIA) is a multi-kiloampere compact electron accelerator. It uses linear induction accelerator modules on the straight sections of a racetrack spiral, with strong-focusing bends to recirculate the electrons. The strong focusing is provided by stellarator windings on the bends. Stellarator coils are used to provide the strong focusing on the bends. The matching of the electron beam from a diode through a series of accelerator modules and stellarator bends is a major issue in the design of this accelerator. The beam line design for a proof-of-concept SLIA experiment (10 kA, 7 MeV) to be carried out at Pulse Sciences, Inc. will be presented. The design will demonstrate beam matching from element to element in the focusing system, the design of an achromatic bend, and the requirements for avoiding collective instabilities

  19. Remote mechanical C line

    Nuttall, K.R.; Gardner, P.R.

    1991-01-01

    Westinghouse Hanford Company is developing a desk-top simulation based training program on the operation of the Remote Mechanical C (RMC) Line process in the Plutonium Finishing Plant on the Hanford site, Richland, Washington. Simulations display aod contioually update current values of system parameters on computer graphics of RMC line equipment. Students are able to operate a variety of controllers to maintain proper system status. Programmed faults, selectable by the course instructor, can be used to test student responses to off-normal events. Prior to operation of the simulation, students are given computer-based tutorials on the function, processes, operation, and error conditions associated with individual components. By including the capability of operating each individual component - valves, heaters, agitators, etc. - the computer-based training (CBT) lessons become an interactive training manual. From one perspective RMC represents one step in the diffusion of the well-known and well-documented simulator training activities for nuclear reactor operators to other training programs, equally critical, perhaps, but less well scrutinized in the past. Because of the slowly responding nature of the actual process, RMC can retain many of the capabilities of practice and testing in a simulated work environment while avoiding the cost of a full scale simulator and the exposure and waste developed by practice runs of the RMC line. From another perspective RMC suggests training advances even beyond the most faithful simulators. For example, by integrating CBT lessons with the simulation, RMC permits students to focus in on specific processes occurring inside chosen components. In effect, the interactive training manual is available on-line with the simulation itself. Cost are also discussed

  20. Pink-line syndrome

    Ravindran J.; Raghukumar, C.; Manikandan, B.

    , a physiological crisis in the scleractinian coral Porites lutea. Marine biology 149: 347-356 7. Ravindran J, Raghukumar C (2006a) Histological observations on the scleractinian coral Porites lutea affected by pink-line syndrome. Current science... handbook: guidelines for assessment and monitoring. Currie Communications, Melbourne, Australia, 94p+App 10. Vargas-Angel B, Wheeler B (2009) Coral health and disease assessment in the US Pacific territories and affiliated states. Proc. 11th Coral Reef...

  1. Line managers as marketers.

    Rynne, T J

    1986-09-01

    Many hospital administrators and boards of directors, having overcome their initial opposition to advertising and hired a marketing professional, are wondering why their marketing programs have not accomplished all that they had hoped. The answer lies in their perception of who is responsible for marketing. Marketing is not a specialty separate from the disciplines of management--it is a basic management skill. Its goal is to satisfy the customer by providing products and services that meet the customer's needs, wants, and preferences. Line managers must understand the hospital's customers and make the critical day-to-day differences in satisfying them. They are the hospital's front-line marketers, and the marketing department's role is to support them in this function. The marketing department should develop the line managers' marketing skills by furnishing them with the appropriate tools: formats, models, examples, and instructions. In addition, the marketing staff should provide such specialized services as marketing research, ad agency management, and development of communications.

  2. Spectrophotometry of Epsilon Aur, 3295-8880 A

    Lockwood, G. W.; Thompson, D. T.; Lutz, B. L.; Sowell, J.

    1985-01-01

    Spectrophotometric scans were obtained at 8 A resolution from 3295 to 8880 A on twenty nights before, during, and after the recent eclipse of epsilon Aurigae, beginning with a pre-eclipse observation on 5 March 1982 U.T. The observations were reduced to absolute flux using the standard stars 109 Vir or xi(2) Ceti. The data confirm that the eclipse is essentially gray over the entire visible spectrum, as others have noted from broadband photometry. High resolution echellograms (450 to 6700 A) made through mid-eclipse and the scans show changes in the equivalent widths of H alpha, Na D, and O I as large as a factor of two.

  3. Coaxial transmission line - Equalization

    Bonnerue, J.L.; Fremont, Jacques; Haubtmann, Jack; Pillon, Gerard.

    1981-09-01

    The transmission of electrical signal through a coaxial line is not perfect and signal distortions are increased as much as the frequency spectrum is extended. We have designed and achieved passive filters (named equalizers) with transfer functions which are inverse of coaxial transfer functions. Doing so our attempt is to avoid definitive loss of information in the recorded data. The main feature of our equalization method lies in the fact it could be either an electrical or a numerical correction or both of them. Some examples in the use of this technique are also proposed [fr

  4. α-line systematics

    Caurier, E.; Zuker, A.P.

    1991-01-01

    A study of the α-line, defined as a set of differences (D α ) characterized binding energies of (N,Z) nuclei, is presented. The 2p2n-separation energies for even-even nuclei, odd-odd nuclei, even(Z)-odd(N) nuclei, odd(Z)-even(N) nuclei are presented. Trends and details in even-even nuclei, magic numbers of even-even and odd-odd nuclei are discussed. (G.P.) 1 ref.; 8 figs

  5. Can antibiotic prescriptions in respiratory tract infections be improved? A cluster-randomized educational intervention in general practice – The Prescription Peer Academic Detailing (Rx-PAD Study [NCT00272155

    Rognstad Sture

    2006-06-01

    Full Text Available Abstract Background More than half of all antibiotic prescriptions in general practice are issued for respiratory tract infections (RTIs, despite convincing evidence that many of these infections are caused by viruses. Frequent misuse of antimicrobial agents is of great global health concern, as we face an emerging worldwide threat of bacterial antibiotic resistance. There is an increasing need to identify determinants and patterns of antibiotic prescribing, in order to identify where clinical practice can be improved. Methods/Design Approximately 80 peer continuing medical education (CME groups in southern Norway will be recruited to a cluster randomized trial. Participating groups will be randomized either to an intervention- or a control group. A multifaceted intervention has been tailored, where key components are educational outreach visits to the CME-groups, work-shops, audit and feedback. Prescription Peer Academic Detailers (Rx-PADs, who are trained GPs, will conduct the educational outreach visits. During these visits, evidence-based recommendations of antibiotic prescriptions for RTIs will be presented and software will be handed out for installation in participants PCs, enabling collection of prescription data. These data will subsequently be linked to corresponding data from the Norwegian Prescription Database (NorPD. Individual feedback reports will be sent all participating GPs during and one year after the intervention. Main outcomes are baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline one year after the initiation of the tailored pedagogic intervention. Discussion Improvement of prescription patterns in medical practice is a challenging task. A thorough evaluation of guidelines for antibiotic treatment in RTIs may impose important benefits, whereas inappropriate prescribing entails substantial costs, as well as undesirable consequences like development

  6. MO-DE-BRA-05: EUTEMPE-RX: Combining E-Learning and Face-To-Face Training to Build Expert Knowledge, Skills and Competences for Medical Physicists in Diagnostic and Interventional Radiology

    Bosmans, H; Van Peteghem, N; Creten, S; Mackenzie, A; Vano, E; Borowski, M; Christofides, S; Caruana, C

    2016-01-01

    also beyond Europe. The EUTEMPE-RX project is funded by the Horizon2020 - EURATOM program of the European Commission

  7. A DETAILED STUDY OF THE MOLECULAR AND ATOMIC GAS TOWARD THE {gamma}-RAY SUPERNOVA REMNANT RX J1713.7-3946: SPATIAL TeV {gamma}-RAY AND INTERSTELLAR MEDIUM GAS CORRESPONDENCE

    Fukui, Y.; Sano, H.; Sato, J.; Torii, K.; Horachi, H.; Hayakawa, T.; Inutsuka, S.; Kawamura, A.; Yamamoto, H.; Okuda, T.; Mizuno, N.; Onishi, T. [Department of Physics and Astrophysics, Nagoya University, Nagoya, Aichi 464-8601 (Japan); McClure-Griffiths, N. M. [CSIRO Astronomy and Space Science, Epping NSW 1710 (Australia); Rowell, G. [School of Chemistry and Physics, University of Adelaide, Adelaide 5005 (Australia); Inoue, T. [Department of Physics and Mathematics, Aoyama Gakuin University, Sagamihara, Kanagawa 252-5258 (Japan); Mizuno, A. [Solar-Terrestrial Environment Laboratory, Nagoya University, Nagoya, Aichi 464-8601 (Japan); Ogawa, H., E-mail: fukui@a.phys.nagoya-u.ac.jp [Department of Astrophysics, Graduate School of Science, Osaka Prefecture University, Sakai, Osaka 599-8531 (Japan)

    2012-02-10

    RX J1713.7-3946 is the most remarkable TeV {gamma}-ray supernova remnant (SNR) that emits {gamma}-rays in the highest energy range. We have made a new combined analysis of CO and H I in the SNR and derived the total protons in the interstellar medium (ISM). We have found that the inclusion of the H I gas provides a significantly better spatial match between the TeV {gamma}-rays and ISM protons than the H{sub 2} gas alone. In particular, the southeastern rim of the {gamma}-ray shell has a counterpart only in the H I. The finding shows that the ISM proton distribution is consistent with the hadronic scenario that cosmic-ray (CR) protons react with ISM protons to produce the {gamma}-rays. This provides another step forward for the hadronic origin of the {gamma}-rays by offering one of the necessary conditions missing in the previous hadronic interpretations. We argue that the highly inhomogeneous distribution of the ISM protons is crucial in the origin of the {gamma}-rays. Most of the neutral gas was likely swept up by the stellar wind of an OB star prior to the supernova (SN) explosion to form a low-density cavity and a swept-up dense wall. The cavity explains the low-density site where the diffusive shock acceleration of charged particles takes place with suppressed thermal X-rays, whereas the CR protons can reach the target protons in the wall to produce the {gamma}-rays. The present finding allows us to estimate the total CR proton energy to be {approx}10{sup 48} erg, 0.1% of the total energy of the SN explosion.

  8. MO-DE-BRA-05: EUTEMPE-RX: Combining E-Learning and Face-To-Face Training to Build Expert Knowledge, Skills and Competences for Medical Physicists in Diagnostic and Interventional Radiology

    Bosmans, H [University Hospitals Leuven, Leuven (Belgium); Van Peteghem, N; Creten, S [KU Leuven, Leuven, Vlaams Brabant (Belgium); Mackenzie, A [Royal Surrey County Hospital, Guildford, Surrey (United Kingdom); Vano, E [San Carlos University Hospital, Madrid (Spain); Borowski, M [Klinikum Braunschweig, Braunschweig (Germany); Christofides, S [Nicosia General Hospital, Nicosia (Cyprus); Caruana, C [University of Malta, Msida (Malta)

    2016-06-15

    also beyond Europe. The EUTEMPE-RX project is funded by the Horizon2020 - EURATOM program of the European Commission.

  9. From Off-line to On-line Handwriting Recognition

    Lallican, P.; Viard-Gaudin, C.; Knerr, S.

    2004-01-01

    On-line handwriting includes more information on time order of the writing signal and on the dynamics of the writing process than off-line handwriting. Therefore, on-line recognition systems achieve higher recognition rates. This can be concluded from results reported in the literature, and has been

  10. The innominate line

    Whelan, M.A.; Myung, K.H.; Bergeron, R.T.

    1984-01-01

    The innominate line continues to be of value in evaluating the integrity of the sphenoid bone since plain skull radiographs remain a primary screening tool for metastatic disease, seizure disorder and headache. The detection of lesions involving the sphenoid bone can be difficult. The accuracy of the radionulcide scan is reduced because of confusion caused by uptake in the adjacent nasal and sinus mucosa. On computed tomography, the sections through the base of the skull and orbit can contain many artifictual densities caused by a combination of bone, soft tissue and sinus air interfaces. In addition, routine settings of window width and level on CT scan are designed to best demonstrate the soft tissues, and bony lesions can easily be missed. Thus, disruption of the ''integrity'' of this line on plain films, particularly the Caldwell projection, can be a sensitive first indicator of disease involving the sphenoid bone. Such a determination on plain film leads to more accurate CT scanning, in that attention will be given to the skull base and scans will be imaged with both soft tissue and bone windows. (orig./MG)

  11. Radiation resistant lining material

    Ouchi, Koki; Okagawa, Seigo; Tamaki, Hidehiro.

    1990-01-01

    Rigidity, viscoelasticity, flexibility, radiation resistance, leaching resistance, rust-proofness, endurance, etc. are required for the lining materials to wall surfaces and floor surfaces of facilities used under the effect of radiation rays and for the inner surface protection of vessels for radioactive wastes. The present invention provides radiation resistant lining material capable of satisfying such various requirements in a well-balanced manner. That is, the material contains (A) 100 parts by weight of rapidly curing cement, (B) 50 to 300 % by weight of aggregate, and (C) 80 to 120 parts by weight of polymer emulsion. As the specific example, the ingredient (A) is commercially available under the trade name of Jet Cement. The aggregate of the ingredient (B) has preferably from about 0.6 to 0.2 mm of size and is made of material, preferably, silicon or iron grains. As the ingredient (C), acrylic resin emulsion is preferred. As a result of example, these ingredient constitutions can satisfy each of the required performance described above. (I.S.)

  12. Strategic production line synchronisation

    Hattingh, Teresa

    2016-08-01

    Full Text Available A study was conducted at the sole global producer of suspension struts for a particular vehicle manufacturer. This supplier is currently able to meet customer demand. However, it does so because of a large finished goods and work-in-progress (WIP inventory. The plant operates two production processes that are separated by a large buffer of WIP, which essentially decouples the production processes. This study aimed to reduce this WIP buffer; this would require the processes to become synchronised, bearing in mind that the reliability of delivery should not decrease. A tool that considers time, quality, and machine capacity was developed to assess the impact of line synchronisation on company performance figures. It was found that line synchronisation produced several benefits for the supplier, including batch size reduction, lower inventory levels, and associated shorter lead times. This further allowed the supplier to improve flow in the plant by introducing a pull system. Improved visual oversight could lead to further improved problem-solving and innovation.

  13. Applicazione delle linee guida nazionali nell'attivitá di notifica di casi di legionellosi

    E. Corsano

    2003-05-01

    Full Text Available

    Obiettivi: é noto che effettuare diagnosi di Legionellosi risulta difficile a causa della sovrapposizione della sintomatologia con altre forme di polmonite. Questo spiega, in parte, perché i casi di Legionellosi siano sottostimati. I metodi diagnostici disponibili, sebbene richiedano tempi relativamente lunghi, sono necessari per l’esatta stima di prevalenza della Legionellosi e per gli eventuali interventi preventivi.

    Metodi: nell’Azienda Ospedaliera “G. Panico” di Tricase, seguendo i criteri delle Linee Guida della Legionellosi (G.U. 5 maggio 2000 n. 103 durante la degenza dei pazienti che presentavano segni clinici ed obiettivi di polmonite sono state eseguite indagini radiologiche (Rx Torace, TAC, esami di laboratorio (espettorato, sangue, urina ed avviata terapia antibiotica (macrolidi e cefalosporine di III generazione. L’antigene urinario e le IgG anti-Legionella (metodo IFA, sono stati determinati in collaborazione con il Laboratorio di riferimento Regionale.

    Risultati: nel periodo ottobre 2001 gennaio 2003 sono stati notificati nel nostro ospedale 11 casi di Legionellosi accertati da indagini clinico-strumentali e di laboratorio: tutti i casi avevano titoli anticorpali abbastanza elevati, confermati poi da un secondo controllo a distanza di tempo. Solo due hanno presentato una positività per l’antigene urinario. All’atto della dimissione, per il 63.6% dei casi è stato documentato un miglioramento delle condizioni clinico-laboratoristico-strumentali, nel 18.2% si è avuta una effettiva guarigione. La letalità è stata pari al 18.2%. In tutti casi si è provveduto alla sorveglianza ambientale.

    Considerazioni: i nostri dati evidenziano che i casi di Legionellosi registrati sono stati tutti di tipo comunitario. Una corretta applicazione delle Linee Guida nel sistema di notifica permette l’avvio dell’attività di prevenzione oltre

  14. China's Bilateral Currency Swap Lines

    Zhitao, Lin; Wenjie, Zhan; Cheung, Yin-Wong

    2016-01-01

    We study the determinants of China’s bilateral local currency swap lines that were established since the recent global finance crisis. It is found that economic factors, political considerations, and institutional characteristics including trade intensity, economic size, strategic partnership, free trade agreement, corruption, and stability affect the decision of signing a swap line agreement. Once a swap line agreement decision is made, the size of the swap line is then mainly affected by tr...

  15. Alojamento do granito Lavras e a mineralização aurífera durante evolução de centro vulcano-plutônico pós-colisional, oeste do Escudo Sul-riograndense: dados geofísicos e estruturais

    Maria do Carmo Gastal

    Full Text Available A construção do granito Lavras é analisada mediante integração de dados geológicos, geofísicos e estruturais originais e compilados, em consonância com a evolução do centro vulcano-plutônico. Esse centro engloba o complexo intrusivo Lavras do Sul e a sequência traquiandesítica da Formação Hilário (604 - 590 Ma, ambos formados em posição de antepaís durante o período pós-colisional da Orogênese Dom Feliciano, no oeste do Escudo Sul-riograndense. A análise de estruturas rúpteis e lineamentos magnéticos indica que o vulcanismo teve início próximo ao colapso dessa orogenia, condicionado por sistemas transtensivos dextrais NW-SE a WNW-ESE que invertem para sinistrais com o relaxamento tectônico. A formação do complexo intrusivo, principiando com a intrusão subvulcânica do monzonito Tapera no norte, acompanhou a inversão no regime de stress regional ao longo de zona de falha N70-75°W que o seciona. Ao final, ocorreu o posicionamento do granito Lavras no sul, o qual possui dimensões modestas (325 km³ e forma tabular (comprimento - L: espessura - E ≈ 3:1 afinando para sul, como deduzido dos dados gravimétricos. Dois domínios composicional-estruturais, equivalentes aos granitos magnesianos centrais (granodiorito e monzogranito e os ferrosos da borda (sienogranito e feldspato alcalino granito, são definidos pela trama ASM (anisotropia de suscetibilidade magnética. Tais dados, aliados aos de estruturas rúpteis, apontam um plutonmulticíclico construído em dois eventos de ressurgência, envolvendo: (1 o lacólito central decorrente do alojamento do granodiorito sob a soleira de monzogranito; e (2 as intrusões anulares de granitos ferrosos, induzidas pela expansão do reservatório epizonal em razão da recarga com magmas máfico-ultramáficos lamprofíricos. O controle estrutural, a distribuição espacial e a associação com diques lamprofíricos corroboram o vínculo da mineralização aurífera com o último

  16. Mjollnir Rotational Line Scan Diagnostics.

    1981-05-19

    using long cavity. M8 Removable Pellicle Beam Splitter for He-Ne Lineup Beam. Removed before HF or DF laser is turned on. 27 A 27 * A r of the chopper...three probe laser lines, however three lines were sequentially measured to verify the diagnostic equipment. Two of the three lines have been monitored

  17. CLO : The cell line ontology

    Sarntivijai, Sirarat; Lin, Yu; Xiang, Zuoshuang; Meehan, Terrence F.; Diehl, Alexander D.; Vempati, Uma D.; Schuerer, Stephan C.; Pang, Chao; Malone, James; Parkinson, Helen; Liu, Yue; Takatsuki, Terue; Saijo, Kaoru; Masuya, Hiroshi; Nakamura, Yukio; Brush, Matthew H.; Haendel, Melissa A.; Zheng, Jie; Stoeckert, Christian J.; Peters, Bjoern; Mungall, Christopher J.; Carey, Thomas E.; States, David J.; Athey, Brian D.; He, Yongqun

    2014-01-01

    Background: Cell lines have been widely used in biomedical research. The community-based Cell Line Ontology (CLO) is a member of the OBO Foundry library that covers the domain of cell lines. Since its publication two years ago, significant updates have been made, including new groups joining the CLO

  18. Parallel plate transmission line transformer

    Voeten, S.J.; Brussaard, G.J.H.; Pemen, A.J.M.

    2011-01-01

    A Transmission Line Transformer (TLT) can be used to transform high-voltage nanosecond pulses. These transformers rely on the fact that the length of the pulse is shorter than the transmission lines used. This allows connecting the transmission lines in parallel at the input and in series at the

  19. Topological Acoustic Delay Line

    Zhang, Zhiwang; Tian, Ye; Cheng, Ying; Wei, Qi; Liu, Xiaojun; Christensen, Johan

    2018-03-01

    Topological protected wave engineering in artificially structured media is at the frontier of ongoing metamaterials research that is inspired by quantum mechanics. Acoustic analogues of electronic topological insulators have recently led to a wealth of new opportunities in manipulating sound propagation with strikingly unconventional acoustic edge modes immune to backscattering. Earlier fabrications of topological insulators are characterized by an unreconfigurable geometry and a very narrow frequency response, which severely hinders the exploration and design of useful devices. Here we establish topologically protected sound in reconfigurable phononic crystals that can be switched on and off simply by rotating its three-legged "atoms" without altering the lattice structure. In particular, we engineer robust phase delay defects that take advantage of the ultrabroadband reflection-free sound propagation. Such topological delay lines serve as a paradigm in compact acoustic devices, interconnects, and electroacoustic integrated circuits.

  20. Line broadening by focusing

    Brito, A.L. de; Jabs, A.

    1983-01-01

    It is pointed out that the spectral width of a quasi-monochromatic light beam broadens when the beam is focused. A quantitative formula for this broadening is derived from classical wave theory. The effect is shown to explain some experiments on laser beams done by E. Panarella which that author has explained under the ad-hoc hypothesis that the frequency of the photons changes along with the intensity of the light beam. The line broadening by focusing might also contribute to gas ionization by incident light when the ionization potential is well above the mean photon energy. Some remarks are made on some direct applications of the Heisenberg relations in comparison with our treatment. (Author) [pt

  1. Radiosensitivity of mesothelioma cell lines

    Haekkinen, A.M.; Laasonen, A.; Linnainmaa, K.; Mattson, K.; Pyrhoenen, S.

    1996-01-01

    The present study was carried out in order to examine the radiosensitivity of malignant pleural mesothelioma cell lines. Cell kinetics, radiation-induced delay of the cell cycle and DNA ploidy of the cell lines were also determined. For comparison an HeLa and a human foetal fibroblast cell line were simultaneously explored. Six previously cytogenetically and histologically characterized mesothelioma tumor cell lines were applied. A rapid tiazolyl blue microtiter (MTT) assay was used to analyze radiosensitivity and cell kinetics and DNA ploidy of the cultured cells were determined by flow cytometry. The survival fraction after a dose of 2 Gy (SF2), parameters α and β of the linear quadratic model (LQ-model) and mean inactivation dose (D MID ) were also estimated. The DNA index of four cell lines equaled 1.0 and two cell lines equaled 1.5 and 1.6. Different mesothelioma cell lines showed a great variation in radiosensitivity. Mean survival fraction after a radiation dose of 2 Gy (SF2) was 0.60 and ranged from 0.36 to 0.81 and mean α value was 0.26 (range 0.48-0.083). The SF2 of the most sensitive diploid mesothelioma cell line was 0.36: Less than that of the foetal fibroblast cell line (0.49). The survival fractions (0.81 and 0.74) of the two most resistant cell lines, which also were aneuploid, were equal to that of the HeLa cell line (0.78). The α/β ratios of the most sensitive cell lines were almost an order of magnitude greater than those of the two most resistant cell lines. Radiation-induced delay of the most resistant aneuploid cell line was similar to that of HeLa cells but in the most sensitive (diploid cells) there was practically no entry into the G1 phase following the 2 Gy radiation dose during 36 h. (orig.)

  2. Bipolar pulse forming line

    Rhodes, Mark A.

    2008-10-21

    A bipolar pulse forming transmission line module for linear induction accelerators having first, second, third, fourth, and fifth planar conductors which form an interleaved stack with dielectric layers between the conductors. Each conductor has a first end, and a second end adjacent an acceleration axis. The first and second planar conductors are connected to each other at the second ends, the fourth and fifth planar conductors are connected to each other at the second ends, and the first and fifth planar conductors are connected to each other at the first ends via a shorting plate adjacent the first ends. The third planar conductor is electrically connectable to a high voltage source, and an internal switch functions to short a high voltage from the first end of the third planar conductor to the first end of the fourth planar conductor to produce a bipolar pulse at the acceleration axis with a zero net time integral. Improved access to the switch is enabled by an aperture through the shorting plate and the proximity of the aperture to the switch.

  3. On-line filtering

    Verkerk, C.

    1978-01-01

    Present day electronic detectors used in high energy physics make it possible to obtain high event rates and it is likely that future experiments will face even higher data rates than at present. The complexity of the apparatus increases very rapidly with time and also the criteria for selecting desired events become more and more complex. So complex in fact that the fast trigger system cannot be designed to fully cope with it. The interesting events become thus contaminated with multitudes of uninteresting ones. To distinguish the 'good' events from the often overwhelming background of other events one has to resort to computing techniques. Normally this selection is made in the first part of the analysis of the events, analysis normally performed on a powerful scientific computer. This implies however that many uninteresting or background events have to be recorded during the experiment for subsequent analysis. A number of undesired consequences result; and these constitute a sufficient reason for trying to perform the selection at an earlier stage, in fact ideally before the events are recorded on magnetic tape. This early selection is called 'on-line filtering' and it is the topic of the present lectures. (Auth.)

  4. PEARS Emission Line Galaxies

    Pirzkal, Nor; Rothberg, Barry; Ly, Chun; Rhoads, James E.; Malhotra, Sangeeta; Grogin, Norman A.; Dahlen, Tomas; Meurer, Gerhardt R.; Walsh, Jeremy; Hathi, Nimish P.; hide

    2012-01-01

    We present a full analysis of the Probing Evolution And Reionization Spectroscopically (PEARS) slitless grism spectroscopic data obtained vl'ith the Advanced Camera for Surveys on HST. PEARS covers fields within both the Great Observatories Origins Deep Survey (GOODS) North and South fields, making it ideal as a random surveY of galaxies, as well as the availability of a wide variety of ancillary observations to support the spectroscopic results. Using the PEARS data we are able to identify star forming galaxies within the redshift volume 0 galaxies down to a limiting flux of approx 10 - 18 erg/s/sq cm . The ELRs have also been compared to the properties of the host galaxy, including morphology, luminosity, and mass. From this analysis we find three key results: 1) The computed line luminosities show evidence of a flattening in the luminosity function with increasing redshift; 2) The star forming systems show evidence of disturbed morphologies, with star formation occurring predominantly within one effective (half-light) radius. However, the morphologies show no correlation with host stellar mass; and 3) The number density of star forming galaxies with M(*) >= 10(exp 9) Solar M decreases by an order of magnitude at z<=0.5 relative to the number at 0.5 < z < 0.9 in support of the argument for galaxy downsizing.

  5. Optimization of line configuration and balancing for flexible machining lines

    Liu, Xuemei; Li, Aiping; Chen, Zurui

    2016-05-01

    Line configuration and balancing is to select the type of line and allot a given set of operations as well as machines to a sequence of workstations to realize high-efficiency production. Most of the current researches for machining line configuration and balancing problems are related to dedicated transfer lines with dedicated machine workstations. With growing trends towards great product variety and fluctuations in market demand, dedicated transfer lines are being replaced with flexible machining line composed of identical CNC machines. This paper deals with the line configuration and balancing problem for flexible machining lines. The objective is to assign operations to workstations and find the sequence of execution, specify the number of machines in each workstation while minimizing the line cycle time and total number of machines. This problem is subject to precedence, clustering, accessibility and capacity constraints among the features, operations, setups and workstations. The mathematical model and heuristic algorithm based on feature group strategy and polychromatic sets theory are presented to find an optimal solution. The feature group strategy and polychromatic sets theory are used to establish constraint model. A heuristic operations sequencing and assignment algorithm is given. An industrial case study is carried out, and multiple optimal solutions in different line configurations are obtained. The case studying results show that the solutions with shorter cycle time and higher line balancing rate demonstrate the feasibility and effectiveness of the proposed algorithm. This research proposes a heuristic line configuration and balancing algorithm based on feature group strategy and polychromatic sets theory which is able to provide better solutions while achieving an improvement in computing time.

  6. Alternate Double Single Track Lines

    Moraga Contreras, P.; Grande Andrade, Z.; Castillo Ron, E.

    2016-07-01

    The paper discusses the advantages and shortcomings of alternate double single track (ADST) lines with respect to double track lines for high speed lines. ADST lines consists of sequences of double and single track segments optimally selected in order to reduce the construction and maintenance costs of railway lines and to optimize the timetables used to satisfy a given demand. The single tracks are selected to coincide with expensive segments (tunnels and viaducts) and the double tracks are chosen to coincide with flat areas and only where they are necessary. At the same time, departure times are adjusted for trains to cross at the cheap double track segments. This alternative can be used for new lines and also for existing conventional lines where some new tracks are to be constructed to reduce travel time (increase speed). The ADST proposal is illustrated with some examples of both types (new lines and where conventional lines exist), including the Palencia-Santander, the Santiago-Valparaíso-Viña del Mar and the Dublin-Belfast lines, where very important reductions (90 %) are obtained, especially where a railway infrastructure already exist. (Author)

  7. On line portal imaging

    Munro, Peter

    1997-01-01

    Purpose/Objective: The purpose of this presentation is to examine the various imaging devices that have been developed for portal imaging, describe some of the image registration methods that have been developed to determine geometric errors quantitatively, and discuss how portal imaging has been incorporated into clinical practice. Discussion: Verification of patient positioning has always been an important aspect of external beam radiation therapy. Over the past decade many portal imaging devices have been developed by individual investigators and most accelerator manufacturers now offer 'on-line' portal imaging systems. The commercial devices include T.V. camera-based systems, liquid ionisation chamber systems, and shortly, flat panel systems. The characteristics of these imaging systems will be discussed. In addition, other approaches such as the use of kilovoltage x-ray sources, video monitoring, and ultrasound have been proposed for improving patient positioning. Some of the advantages of these approaches will be discussed. One of the major advantages of on-line portal imaging is that many quantitative techniques have been developed to detect errors in patient positioning. The general approach is to register anatomic structures on a portal image with the same structures on a digitized simulator film. Once the anatomic structures have been registered, any discrepancies in the position of the patient can be identified. One problem is finding a common frame of reference for the simulator and portal images, since the location of the radiation field within the pixel matrix may differ for the two images. As a result, a common frame of reference has to be established before the anatomic structures in the images can be registered - generally by registering radiation field edges identified in the simulator and portal images. In addition, distortions in patient geometry or rotations out of the image plane can confound the image registration techniques. Despite the

  8. On line portal imaging

    Munro, Peter

    1996-01-01

    Purpose/Objective: The purpose of this presentation is to examine the various imaging devices that have been developed for portal imaging; describe some of the image registration methods that have been developed to determine geometric errors quantitatively; discuss some of the ways that portal imaging has been incorporated into routine clinical practice; describe quality assurance procedures for these devices, and discuss the use of portal imaging devices for dosimetry applications. Discussion: Verification of patient positioning has always been an important aspect of external beam radiation therapy. Over the past decade many portal imaging devices have been developed by individual investigators and most accelerator manufacturers now offer 'on-line' portal imaging systems. The commercial devices can be classified into three categories: T.V. camera-based systems, liquid ionisation chamber systems, and amorphous silicon systems. Many factors influence the quality of images generated by these portal imaging systems. These include factors which are unavoidable (e.g., low subject contrast), factors which depend upon the individual imaging device forming the image (e.g., dose utilisation, spatial resolution) as well as factors which depend upon the characteristics of the linear accelerator irradiating the imaging system (x-ray source size, image magnification). The characteristics of individual imaging systems, such as spatial resolution, temporal response, and quantum utilisation will be discussed. One of the major advantages of on-line portal imaging is that many quantitative techniques have been developed to detect errors in patient positioning. The general approach is to register anatomic structures on a portal image with the same structures on a digitized simulator film. Once the anatomic structures have been registered, any discrepancies in the position of the patient can be identified. However, the task is not nearly as straight-forward as it sounds. One problem

  9. Rapid line scan MR angiography

    Frahm, J.; Merboldt, K.D.; Hanicke, W.; Bruhn, H.

    1987-01-01

    Direct MR angiography may be performed using line scan imaging techniques combined with presaturation of stationary spins. Thus, a single line scan echo yields a projection of vessels due to the signal from reflowing unsaturated spins. Reconstruction of an angiographic image is performed line by line at slightly incremented positions. In particular, line scan angiography is direct and fast without a sensitivity to artifacts even for high flow rates. Image resolution and field of view may be chosen without restrictions, and zoom images using enhanced gradients may be recorded without aliasing artifacts. The method is robust with respect to eddy currents and pulsatile flow. Line scan MR angiograms of phantoms, animals, and human volunteers have been recorded using 90 0 radio frequency pulses and gradient-recalled echoes

  10. Design of LEIR Transfer Lines

    Carli, Ch; Hemery, J-Y

    2002-01-01

    The LEIR transfer lines are designed to transport the ion beam from the Linac 3 to LEIR and, after accumulation and acceleration from LEIR to the PS. A part of the transfer line is used for both, injection and extraction. Thus, it is natural to design injection and extraction optics in common. Beside optics constraints, the geometry of the existing machines (Linac 3, LEIR and PS) and transfer tunnels have to be respected. A new proposal for the LEIR transfer lines is presented.

  11. On line portal imaging

    Munro, Peter

    1995-01-01

    Purpose/Objective: The purpose of this presentation is to review the physics of imaging with high energy x-ray beams; examine the various imaging devices that have been developed for portal imaging; describe some of the image registration methods that have been developed to determine errors in patient positioning quantitatively; and discuss some of the ways that portal imaging has been incorporated into routine clinical practice. Verification of patient positioning has always been an important aspect of external beam radiation therapy. Checks of patient positioning have generally been done with film, however, film suffers from a number of drawbacks, such as poor image display and delays due to film development. Over the past decade many portal imaging devices have been developed by individual investigators and most accelerator manufacturers now offer 'on-line' portal imaging systems, which are intended to overcome the limitations of portal films. The commercial devices can be classified into three categories: T.V. camera-based systems, liquid ionisation chamber systems, and amorphous silicon systems. Many factors influence the quality of images generated by these portal imaging systems. These include factors which are unavoidable (e.g., low subject contrast), factors which depend upon the individual imaging device forming the image (e.g., dose utilisation, spatial resolution) as well as factors which depend upon the characteristics of the linear accelerator irradiating the imaging system (x-ray source size, image magnification). The fundamental factors which limit image quality and the characteristics of individual imaging systems, such as spatial resolution, temporal response, and quantum utilisation will be discussed. One of the major advantages of on-line portal imaging is that many quantitative techniques have been developed to detect errors in patient positioning. The general approach is to register anatomic structures on a portal image with the same

  12. Antibiotic RX in Hospitals: Proceed with Caution

    2014-03-04

    This podcast is based on the March 2014 CDC Vital Signs report. Antibiotics save lives, but poor prescribing practices can put patients at risk for health problems. Learn how to protect patients by protecting antibiotics.  Created: 3/4/2014 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 3/4/2014.

  13. Medical Humanities: The Rx for Uncertainty?

    Ofri, Danielle

    2017-12-01

    While medical students often fear the avalanche of knowledge they are required to learn during training, it is learning to translate that knowledge into wisdom that is the greatest challenge of becoming a doctor. Part of that challenge is learning to tolerate ambiguity and uncertainty, a difficult feat for doctors who are taught to question anything that is not evidence based or peer reviewed. The medical humanities specialize in this ambiguity and uncertainty, which are hallmarks of actual clinical practice but rarely addressed in medical education. The humanities also force reflection and contemplation-skills that are crucial to thoughtful decision making and to personal wellness. Beyond that, the humanities add a dose of joy and beauty to a training process that is notoriously frugal in these departments. Well integrated, the humanities can be the key to transforming medical knowledge into clinical wisdom.

  14. Rx for a Healthy School Nutrition Program

    Boettger, Julie

    2009-01-01

    School nutrition directors face challenges on many fronts, from changing nutrition standards to addressing community interest in sustainability and local food sourcing. Programs are constantly changing to meet these new demands. How does a school business administrator know which changes will affect his/her school nutrition program positively? The…

  15. Similarity law for Widom lines and coexistence lines.

    Banuti, D T; Raju, M; Ihme, M

    2017-05-01

    The coexistence line of a fluid separates liquid and gaseous states at subcritical pressures, ending at the critical point. Only recently, it became clear that the supercritical state space can likewise be divided into regions with liquidlike and gaslike properties, separated by an extension to the coexistence line. This crossover line is commonly referred to as the Widom line, and is characterized by large changes in density or enthalpy, manifesting as maxima in the thermodynamic response functions. Thus, a reliable representation of the coexistence line and the Widom line is important for sub- and supercritical applications that depend on an accurate prediction of fluid properties. While it is known for subcritical pressures that nondimensionalization with the respective species critical pressures p_{cr} and temperatures T_{cr} only collapses coexistence line data for simple fluids, this approach is used for Widom lines of all fluids. However, we show here that the Widom line does not adhere to the corresponding states principle, but instead to the extended corresponding states principle. We resolve this problem in two steps. First, we propose a Widom line functional based on the Clapeyron equation and derive an analytical, species specific expression for the only parameter from the Soave-Redlich-Kwong equation of state. This parameter is a function of the acentric factor ω and compares well with experimental data. Second, we introduce the scaled reduced pressure p_{r}^{*} to replace the previously used reduced pressure p_{r}=p/p_{cr}. We show that p_{r}^{*} is a function of the acentric factor only and can thus be readily determined from fluid property tables. It collapses both subcritical coexistence line and supercritical Widom line data over a wide range of species with acentric factors ranging from -0.38 (helium) to 0.34 (water), including alkanes up to n-hexane. By using p_{r}^{*}, the extended corresponding states principle can be applied within

  16. Fractions, Number Lines, Third Graders

    Cramer, Kathleen; Ahrendt, Sue; Monson, Debra; Wyberg, Terry; Colum, Karen

    2017-01-01

    The Common Core State Standards for Mathematics (CCSSM) (CCSSI 2010) outlines ambitious goals for fraction learning, starting in third grade, that include the use of the number line model. Understanding and constructing fractions on a number line are particularly complex tasks. The current work of the authors centers on ways to successfully…

  17. Mechanical Behaviour of Lined Pipe

    Hilberink, A.

    2011-01-01

    Installing lined pipe by means of the reeling installation method seems to be an attractive combination, because it provides the opportunity of eliminating the demanding welds from the critical time offshore and instead preparing them onshore. However, reeling of lined pipe is not yet proven

  18. Marine line fish research programme

    SANCOR

    1979-04-01

    Full Text Available This report outlines the framework for a marine line fish programme under the aegis of the South African National Committee for Oceanographic Research (SANCOR). An attempt is made to assess the state of knowledge about South African marine line...

  19. A tangent subsolar merging line

    Crooker, N.U.; Siscoe, G.L.; Toffoletto, F.R.

    1990-01-01

    The authors describe a global magnetospheric model with a single subsolar merging line whose position is determined neither locally by the relative orientations and strengths of the merging fields nor globally by the orientation of a separator line--the governing parameters of most previous models--but by the condition of tangential contact between the external field and the magnetopause. As in previous models, the tilt of the merging line varies with IMF orientation, but here it also depends upon the ratio of Earth's magnetic flux that leaks out of the magnetopause to IMF flux that penetrates in. In the limiting case treated by Alekseyev and Belen'kaya, with no leakage of Earth's field and total IMF penetration, the merging line forms a great circle around a spherical magnetosphere where undeviated IMF lines lie tangent to its surface. This tangent merging line lies perpendicular to the IMF. They extend their work to the case of finite leakage and partial penetration, which distort the IMF into a draped pattern, thus changing the locus of tangency to the sphere. In the special case where the penetrating IMF flux is balanced by an equal amount of Earth flux leakage, the tangent merging line bisects the angle between the IMF and Earth's northward subsolar field. This result is identical to the local merging line model result for merging fields with equal magnitude. Here a global flux balance condition replaces the local equal magnitude condition

  20. Radiosensitivity of mesothelioma cell lines

    Haekkinen, A.M. [Dept. of Oncology, Univ. Central Hospital, Helsinki (Finland); Laasonen, A. [Dept. of Pathology, Central Hospital of Etelae-Pohjanmaa, Seinaejoki (Finland); Linnainmaa, K. [Dept. of Industrial Hygiene and Toxicology, Inst. of Occupational Health, Helsinki (Finland); Mattson, K. [Dept. Pulmonary Medicine, Univ. Central Hospital, Helsinki (Finland); Pyrhoenen, S. [Dept. of Oncology, Univ. Central Hospital, Helsinki (Finland)

    1996-10-01

    The present study was carried out in order to examine the radiosensitivity of malignant pleural mesothelioma cell lines. Cell kinetics, radiation-induced delay of the cell cycle and DNA ploidy of the cell lines were also determined. For comparison an HeLa and a human foetal fibroblast cell line were simultaneously explored. Six previously cytogenetically and histologically characterized mesothelioma tumor cell lines were applied. A rapid tiazolyl blue microtiter (MTT) assay was used to analyze radiosensitivity and cell kinetics and DNA ploidy of the cultured cells were determined by flow cytometry. The survival fraction after a dose of 2 Gy (SF2), parameters {alpha} and {beta} of the linear quadratic model (LQ-model) and mean inactivation dose (D{sub MID}) were also estimated. The DNA index of four cell lines equaled 1.0 and two cell lines equaled 1.5 and 1.6. Different mesothelioma cell lines showed a great variation in radiosensitivity. Mean survival fraction after a radiation dose of 2 Gy (SF2) was 0.60 and ranged from 0.36 to 0.81 and mean {alpha} value was 0.26 (range 0.48-0.083). The SF2 of the most sensitive diploid mesothelioma cell line was 0.36: Less than that of the foetal fibroblast cell line (0.49). The survival fractions (0.81 and 0.74) of the two most resistant cell lines, which also were aneuploid, were equal to that of the HeLa cell line (0.78). The {alpha}/{beta} ratios of the most sensitive cell lines were almost an order of magnitude greater than those of the two most resistant cell lines. Radiation-induced delay of the most resistant aneuploid cell line was similar to that of HeLa cells but in the most sensitive (diploid cells) there was practically no entry into the G1 phase following the 2 Gy radiation dose during 36 h. (orig.).

  1. Teaching Braille Line Tracking Using Stimulus Fading

    Scheithauer, Mindy C.; Tiger, Jeffrey H.

    2014-01-01

    Line tracking is a prerequisite skill for braille literacy that involves moving one's finger horizontally across a line of braille text and identifying when a line ends so the reader may reset his or her finger on the subsequent line. Current procedures for teaching line tracking are incomplete, because they focus on tracking lines with only…

  2. Atlas transmission line breakdown analysis

    Nielsen, K E; Ballard, E O; Elizondo, J M; Gribble, R F; McCuistian, B T; Parsons, W M

    1999-01-01

    The Atlas facility will use 24 radially converging, vertically oriented and tapered, oil insulated, triplate transmission lines between the Marx generators and the central load region. Among the requirements of the transmission lines are low inductance and high reliability. The inter-conductor gap is nominally 2 cm and the lines taper from a height of 1.75 m at the Marx end to 0.32 m at the output end. The aluminum conductors, held together by 20 insulating spacers, are assembled and inserted as a unit into radial oil-filled steel tanks. The negative, high-voltage, center conductor is 2.54-cm thick and the outer ground conductors are 1.59-cm thick. All 24 triplate transmission lines connect to a transition section at near 1 m radius that couples the transmission lines to a disk/conical solid- dielectric-insulated power flow channel transmission line terminating at the load. Peak operating voltage on the lines can be as high as 240 kV with an effective stress time of 0.8 mu s. Testing of small sections of the ...

  3. rf reference line for PEP

    Schwarz, H.D.; Weaver, J.N.

    1979-03-01

    A rf phase reference line in 6 segments around the 2200 meter circumference PEP storage ring is described. Each segment of the reference line is phase stabilized by its own independent feedback system, which uses an amplitude modulated reflection from the end of each line. The modulation is kept small and decoupled from the next segment to avoid crosstalk and significant modulation of the rf drive signal. An error evaluation of the system is made. The technical implementation and prototype performance are described. Prototype tests indicate that the phase error around the ring can be held below 1 degree with this relatively simple system

  4. rf reference line for PEP

    Schwarz, H.D.; Weaver, J.N.

    1979-03-01

    A rf phase reference line in 6 segments around the 2200 meter circumference PEP storage ring is described. Each segment of the reference line is phase stabilized by its own independent feedback system, which uses an amplitude modulated reflection from the end of each line. The modulation is kept small and decoupled from the next segment to avoid crosstalk and significant modulation of the rf drive signal. An error evaluation of the system is made. The technical implementation and prototype performance are described. Prototype tests indicate that the phase error around the ring can be held below 1 degree with this relatively simple system.

  5. Status of ACCULINNA beam line

    Rodin, A M; Bogdanov, D D; Golovkov, M S; Fomichev, A S; Sidorchuk, S I; Slepnev, R S; Wolski, R; Ter-Akopian, G M; Oganessian, Yu T; Yukhimchuk, A A; Perevozchikov, V V; Vinogradov, Yu I; Grishenchkin, S K; Demin, A M; Zlatoustovskii, S V; Kuryakin, A V; Filchagin, S V; Ilkaev, R I

    2003-01-01

    The separator ACCULINNA was upgraded to achieve new experimental requirements. The beam line was extended by new ion-optical elements beyond the cyclotron hall. The new arrangements yield much better background conditions. The intensities of sup 6 He and sup 8 He radioactive beams produced in fragmentation of 35 A MeV sup 1 sup 1 B ions were increased up to a factor of 10. The upgraded beam line was used in experiments to study the sup 5 H resonance states populated in the t+t reaction. A cryogenic liquid tritium target was designed and installed at the separator beam line.

  6. Analysis of some coplanar transmission lines: coplanar coupled lines, coplanar coupled striplines, and coplanar coupled lines with rectangular microshield

    Yuan, Naichang; He, Jianguo; Yao, Demiao; Dai, Qin; Lin, Weigan

    1995-06-01

    Two types of coplanar transmission lines, rectangular microshield coplanar coupled lines (RMCCL) and coplanar coupled rectangular microshield lines (CCRML), are proposed for MMIC applications. These are developed from coplanar coupled lines (CCL) and coplanar coupled strip lines (CCS). Analytic formulas are presented for calculating the quasistatic TEM parameters of these coupled lines by means of exact conformal mapping techniques. Numerical results are also presented to illustrate the properties of these coplanar transmission lines.

  7. Using a tailored health information technology- driven intervention to improve health literacy and medication adherence in a Pakistani population with vascular disease (Talking Rx) - study protocol for a randomized controlled trial.

    Kamal, Ayeesha Kamran; Muqeet, Abdul; Farhat, Kashfa; Khalid, Wardah; Jamil, Anum; Gowani, Ambreen; Muhammad, Aliya Amin; Zaidi, Fabiha; Khan, Danyal; Elahi, Touseef; Sharif, Shahrukh; Raz, Sibtain; Zafar, Taha; Bokhari, Syedah Saira; Rahman, Nasir; Sultan, Fateh Ali Tipoo; Sayani, Saleem; Virani, Salim S

    2016-03-05

    Vascular disease, manifesting as myocardial infarction and stroke, is a major cause of morbidity and mortality, especially in low- and middle-income countries. Current estimates are that only one in six patients have good adherence to medications and very few have sufficient health literacy. Our aim is to explore the effectiveness and acceptability of Prescription Interactive Voice Response (IVR) Talking Prescriptions (Talking Rx) and SMS reminders in increasing medication adherence and health literacy in Pakistani patients with vascular disease. This is a randomized, controlled, single center trial. Adult participants, with access to a cell phone and a history of vascular disease, taking multiple risk-modifying medications (inclusive of anti-platelets and statins) will be selected from cerebrovascular and cardiovascular clinics. They will be randomized in a 1:1 ratio via a block design to the intervention or the control arm with both groups having access to a helpline number to address their queries in addition to standard of care as per institutional guidelines. Participants in the intervention group will also have access to Interactive Voice Response (IVR) technology tailored to their respective prescriptions in the native language (Urdu) and will have the ability to hear information about their medication dosage, correct use, side effects, mechanism of action and how and why they should use their medication, as many times as they like. Participants in the intervention arm will also receive scheduled SMS messages reminding them to take their medications. The primary outcome measure will be the comparison of the difference in adherence to anti-platelet and statin medication between baseline and at 3-month follow-up in each group measured by the Morisky Medication Adherence Scale. To ascertain the impact of our intervention on health literacy, we will also compare a local content-validated and modified version of Test of Health Literacy in Adults (TOFHLA) between

  8. Animated construction of line drawings

    Fu, Hongbo; Zhou, Shizhe; Liu, Ligang; Mitra, Niloy J.

    2011-01-01

    Revealing the sketching sequence of a line drawing can be visually intriguing and used for video-based storytelling. Typically this is enabled based on tedious recording of artists' drawing process. We demonstrate that it is often possible

  9. Animated construction of line drawings

    Fu, Hongbo; Zhou, Shizhe; Liu, Ligang; Mitra, Niloy J.

    2011-01-01

    system produces plausible animated constructions of input line drawings, with no or little user intervention. We test our algorithm on a range of input sketches, with varying degree of complexity and structure, and evaluate the results via a user study

  10. Composite Materials in Overhead Lines

    Sørensen, Thomas Kjærsgaard; Holbøll, Joachim

    2009-01-01

    towers and recently conductors based on composite materials are available at transmission levels. In this paper it is investigated which composite based solutions are available in connection with complete overhead line systems including insulators, towers and conductors. The components are reviewed......The use of composite materials, e.g. fibreglass materials, in overhead transmission line systems is nothing new. Composite based insulators have been applied to transmission lines for over 30 years, mainly as suspension and post insulators and often as an option for special applications. Also...... with respect to solved and persisting known failures/problems of both mechanical and electrical nature. Major challenges related to extensive use of composite materials in an overhead line system are identified, as are possible benefits - both when using standard as well as customised composite components, e...

  11. Louisiana ESI: ROADS (Road Lines)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains the state maintained primary and secondary road network of Louisiana. Vector lines in the data set represent Interstates, U.S. Highways, and...

  12. Control Point Generated PLS - lines

    Minnesota Department of Natural Resources — The Control Point Generated PLS layer contains line and polygon features to the 1/4 of 1/4 PLS section (approximately 40 acres) and government lot level. The layer...

  13. Railroad Lines, US, 2015, NAVTEQ

    U.S. Environmental Protection Agency — NAVTEQ Railroads for the United States. The Railroads layer contains Railroad features published as lines and polylines. Attributes for this layer include the name...

  14. Base Flood Elevation (BFE) Lines

    Department of Homeland Security — The Base Flood Elevation (BFE) table is required for any digital data where BFE lines will be shown on the corresponding Flood Insurance Rate Map (FIRM). Normally if...

  15. Program of telluric lines monitoring

    Vince I.

    2006-01-01

    Full Text Available A new observational program of telluric lines monitoring was introduced at Belgrade Astronomical Observatory. The ultimate goal of this program is to investigate the properties of Earth’s atmosphere through modeling the observed profiles of telluric lines. The program is intend to observe infrared molecular oxygen lines that were selected according to spectral sensitivity of the available CCD camera. In this paper we give the initial and the final selection criteria for spectral lines included in the program the description of equipment and procedures used for observations and reduction, a review of preliminary observational results with the estimated precision, and a short discussion on the comparison of the theoretical predictions and the measurements.

  16. Radio and line transmission 2

    Roddy, Dermot

    2013-01-01

    Radio and Line Transmission, Volume 2 gives a detailed treatment of the subject as well as an introduction to additional advanced subject matter. Organized into 14 chapters, this book begins by explaining the radio wave propagation, signal frequencies, and bandwidth. Subsequent chapters describe the transmission lines and cables; the aerials; tuned and coupled circuits; bipolar transistor amplifiers; field-effect transistors and circuits; thermionic valve amplifiers; LC oscillators; the diode detectors and modulators; and the superheterodyne receiver. Other chapters explore noise and interfere

  17. SAF line analytical chemistry system

    Gerber, E.W.; Sherrell, D.L.

    1983-10-01

    An analytical chemistry system dedicated to supporting the Secure Automated Fabrication (SAF) line is discussed. Several analyses are required prior to the fuel pellets being loaded into cladding tubes to assure certification requirements will be met. These analyses, which will take less than 15 minutes, are described. The automated sample transport system which will be used to move pellets from the fabriction line to the chemistry area is also described

  18. QSOs with narrow emission lines

    Baldwin, J.A.; Mcmahon, R.; Hazard, C.; Williams, R.E.

    1988-01-01

    Observations of two new high-redshift, narrow-lined QSOs (NLQSOs) are presented and discussed together with observations of similar objects reported in the literature. Gravitational lensing is ruled out as a possible means of amplifying the luminosity for one of these objects. It is found that the NLQSOs have broad bases on their emission lines as well as the prominent narrow cores which define this class. Thus, these are not pole-on QSOs. The FWHM of the emission lines fits onto the smoothly falling tail of the lower end of the line-width distribution for complete QSO samples. The equivalent widths of the combined broad and narrow components of the lines are normal for QSOs of the luminosity range under study. However, the NLQSOs do show ionization differences from broader-lined QSOs; most significant, the semiforbidden C III/C IV intensity ratio is unusually low. The N/C abundance ratio in these objects is found to be normal; the Al/C abundance ratio may be quite high. 38 references

  19. Polarization of Coronal Forbidden Lines

    Li, Hao; Qu, Zhongquan [Yunnan Observatories, Chinese Academy of Sciences, Kunming, Yunnan 650011 (China); Landi Degl’Innocenti, Egidio, E-mail: sayahoro@ynao.ac.cn [Dipartimento di Astronomia e Scienza dello Spazio, Università di Firenze, Largo E. Fermi 2, I-50125 Firenze (Italy)

    2017-03-20

    Since the magnetic field is responsible for most manifestations of solar activity, one of the most challenging problems in solar physics is the diagnostics of solar magnetic fields, particularly in the outer atmosphere. To this end, it is important to develop rigorous diagnostic tools to interpret polarimetric observations in suitable spectral lines. This paper is devoted to analyzing the diagnostic content of linear polarization imaging observations in coronal forbidden lines. Although this technique is restricted to off-limb observations, it represents a significant tool to diagnose the magnetic field structure in the solar corona, where the magnetic field is intrinsically weak and still poorly known. We adopt the quantum theory of polarized line formation developed in the framework of the density matrix formalism, and synthesize images of the emergent linear polarization signal in coronal forbidden lines using potential-field source-surface magnetic field models. The influence of electronic collisions, active regions, and Thomson scattering on the linear polarization of coronal forbidden lines is also examined. It is found that active regions and Thomson scattering are capable of conspicuously influencing the orientation of the linear polarization. These effects have to be carefully taken into account to increase the accuracy of the field diagnostics. We also found that linear polarization observation in suitable lines can give valuable information on the long-term evolution of the magnetic field in the solar corona.

  20. 76 FR 51367 - China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company Limited; Evergreen Line A...

    2011-08-18

    ... FEDERAL MARITIME COMMISSION [Docket No. 11-12] China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company Limited; Evergreen Line A Joint Service Agreement; Hanjin Shipping Co., Ltd... Maritime Commission (Commission) by China Shipping Container Lines Co., Ltd.; COSCO Container Lines Company...

  1. Building Bridges One Line at a Time

    Grigsby, Cathy Murray

    2012-01-01

    In this article, first-grade students were taught the different kinds of lines that were part of the construction of various bridges--the curved lines of the arches of stone bridges, straight lines connecting the cables of a suspension bridge, vertical lines, horizontal lines, and so on. They gained practice in drawing structures and in fine brush…

  2. Linear morphoea follows Blaschko's lines.

    Weibel, L; Harper, J I

    2008-07-01

    The aetiology of morphoea (or localized scleroderma) remains unknown. It has previously been suggested that lesions of linear morphoea may follow Blaschko's lines and thus reflect an embryological development. However, the distribution of linear morphoea has never been accurately evaluated. We aimed to identify common patterns of clinical presentation in children with linear morphoea and to establish whether linear morphoea follows the lines of Blaschko. A retrospective chart review of 65 children with linear morphoea was performed. According to clinical photographs the skin lesions of these patients were plotted on to standardized head and body charts. With the aid of Adobe Illustrator a final figure was produced including an overlay of all individual lesions which was used for comparison with the published lines of Blaschko. Thirty-four (53%) patients had the en coup de sabre subtype, 27 (41%) presented with linear morphoea on the trunk and/or limbs and four (6%) children had a combination of the two. In 55 (85%) children the skin lesions were confined to one side of the body, showing no preference for either left or right side. On comparing the overlays of all body and head lesions with the original lines of Blaschko there was an excellent correlation. Our data indicate that linear morphoea follows the lines of Blaschko. We hypothesize that in patients with linear morphoea susceptible cells are present in a mosaic state and that exposure to some trigger factor may result in the development of this condition.

  3. Standardization of beam line representations

    Carey, David C.

    1998-01-01

    Standardization of beam line representations means that a single set of data can be used in many situations to represent a beam line. This set of data should be the same no matter what the program to be run or the calculation to be made. We have concerned ourselves with three types of standardization: (1) The same set of data should be usable by different programs. (2) The inclusion of other items in the data, such as calculations to be done, units to be used, or preliminary specifications, should be in a notation similar to the lattice specification. (3) A single set of data should be used to represent a given beam line, no matter what is being modified or calculated. The specifics of what is to be modified or calculated can be edited into the data as part of the calculation. These three requirements all have aspects not previously discussed in a public forum. Implementations into TRANSPORT will be discussed

  4. Linear rotary optical delay lines

    Guerboukha, Hichem; Qu, Hang; Skorobogatiy, Maksim

    2016-03-01

    We present a semi-analytical solution for the design of a high-speed rotary optical delay line that use a combination of two rotating curvilinear reflectors. We demonstrate that it is possible to design an infinite variety of the optical delay lines featuring linear dependence of the optical delay on the rotation angle. This is achieved via shape optimization of the rotating reflector surfaces. Moreover, a convenient spatial separation of the incoming and outgoing beams is possible. For the sake of example, we present blades that fit into a circle of 10cm diameter. Finally, a prototype of a rotary delay line is fabricated using CNC machining, and its optical properties are characterized.

  5. Spent Pot Lining Characterization Framework

    Ospina, Gustavo; Hassan, Mohamed I.

    2017-09-01

    Spent pot lining (SPL) management represents a major concern for aluminum smelters. There are two key elements for spent pot lining management: recycling and safe storage. Spent pot lining waste can potentially have beneficial uses in co-firing in cement plants. Also, safe storage of SPL is of utmost importance. Gas generation of SPL reaction with water and ignition sensitivity must be studied. However, determining the feasibility of SPL co-firing and developing the required procedures for safe storage rely on determining experimentally all the necessary SPL properties along with the appropriate test methods, recognized by emissions standards and fire safety design codes. The applicable regulations and relevant SPL properties for this purpose are presented along with the corresponding test methods.

  6. Animated construction of line drawings

    Fu, Hongbo

    2011-12-01

    Revealing the sketching sequence of a line drawing can be visually intriguing and used for video-based storytelling. Typically this is enabled based on tedious recording of artists\\' drawing process. We demonstrate that it is often possible to estimate a reasonable drawing order from a static line drawing with clearly defined shape geometry, which looks plausible to a human viewer. We map the key principles of drawing order from drawing cognition to computational procedures in our framework. Our system produces plausible animated constructions of input line drawings, with no or little user intervention. We test our algorithm on a range of input sketches, with varying degree of complexity and structure, and evaluate the results via a user study. We also present applications to gesture drawing synthesis and drawing animation creation especially in the context of video scribing.

  7. Animated construction of line drawings

    Fu, Hongbo

    2011-12-01

    Revealing the sketching sequence of a line drawing can be visually intriguing and used for video-based storytelling. Typically this is enabled based on tedious recording of artists\\' drawing process. We demonstrate that it is often possible to estimate a reasonable drawing order from a static line drawing with clearly defined shape geometry, which looks plausible to a human viewer. We map the key principles of drawing order from drawing cognition to computational procedures in our framework. Our system produces plausible animated constructions of input line drawings, with no or little user intervention. We test our algorithm on a range of input sketches, with varying degree of complexity and structure, and evaluate the results via a user study. We also present applications to gesture drawing synthesis and drawing animation creation especially in the context of video scribing. © 2011 ACM.

  8. Standardization of beam line representations

    Carey, David C.

    1999-01-01

    Standardization of beam line representations means that a single set of data can be used in many situations to represent a beam line. This set of data should be the same no matter what the program to be run or the calculation to be made. We have concerned ourselves with three types of standardization: (1) The same set of data should be usable by different programs. (2) The inclusion of other items in the data, such as calculations to be done, units to be used, or preliminary specifications, should be in a notation similar to the lattice specification. (3) A single set of data should be used to represent a given beam line, no matter what is being modified or calculated. The specifics of what is to be modified or calculated can be edited into the data as part of the calculation. These three requirements all have aspects not previously discussed in a public forum. Implementations into TRANSPORT will be discussed

  9. Helium transfer line installation details.

    G. Perinic

    2007-01-01

    A particularity of the 32 m long four in one helium transfer line in between the cold box in USC55 and the cavern UX5 is the fact that the transfer line passes through a hole in the crane rail support beam. In order to ensure the alignment of the suspension rail in the interconnecting tunnel with the hole in the rail support as well as the connection points at both ends required precise measurements of the given geometries as well as the installation of a temporary target for the verification of the theoretical predictions.

  10. Reconnection of magnetic field lines

    Heyn, M.F.; Gratton, F.T.; Gnavi, G.; Heindler, M.

    1990-01-01

    Magnetic field line diffusion in a plasma is studied on the basis of the non-linear boundary layer equations of dissipative, incompressible magnetohydrodynamics. Non-linear steady state solutions for a class of plasma parameters have been obtained which are consistent with the boundary conditions appropriate for reconnection. The solutions are self-consistent in connecting a stagnation point flow of a plasma with reconnecting magnetic field lines. The range of the validity of the solutions, their relation to other fluid models of reconnection, and their possible applications to space plasma configurations are pointed out. (Author)

  11. Assembly line performance and modeling

    Rane, Arun B.; Sunnapwar, Vivek K.

    2017-09-01

    Automobile sector forms the backbone of manufacturing sector. Vehicle assembly line is important section in automobile plant where repetitive tasks are performed one after another at different workstations. In this thesis, a methodology is proposed to reduce cycle time and time loss due to important factors like equipment failure, shortage of inventory, absenteeism, set-up, material handling, rejection and fatigue to improve output within given cost constraints. Various relationships between these factors, corresponding cost and output are established by scientific approach. This methodology is validated in three different vehicle assembly plants. Proposed methodology may help practitioners to optimize the assembly line using lean techniques.

  12. Coiled transmission line pulse generators

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  13. Reconnections of Wave Vortex Lines

    Berry, M. V.; Dennis, M. R.

    2012-01-01

    When wave vortices, that is nodal lines of a complex scalar wavefunction in space, approach transversely, their typical crossing and reconnection is a two-stage process incorporating two well-understood elementary events in which locally coplanar hyperbolas switch branches. The explicit description of this reconnection is a pedagogically useful…

  14. Priming the Mental Time Line

    Di Bono, Maria Grazia; Casarotti, Marco; Priftis, Konstantinos; Gava, Lucia; Umilta, Carlo; Zorzi, Marco

    2012-01-01

    Growing experimental evidence suggests that temporal events are represented on a mental time line, spatially oriented from left to right. Support for the spatial representation of time comes mostly from studies that have used spatially organized responses. Moreover, many of these studies did not avoid possible confounds attributable to target…

  15. Picosecond resolution programmable delay line

    Suchenek, Mariusz

    2009-01-01

    The note presents implementation of a programmable delay line for digital signals. The tested circuit has a subnanosecond delay range programmable with a resolution of picoseconds. Implementation of the circuit was based on low-cost components, easily available on the market. (technical design note)

  16. Managing first-line failure.

    Cooper, David A

    2014-01-01

    WHO standard of care for failure of a first regimen, usually 2N(t)RTI's and an NNRTI, consists of a ritonavir-boosted protease inhibitor with a change in N(t)RTI's. Until recently, there was no evidence to support these recommendations which were based on expert opinion. Two large randomized clinical trials, SECOND LINE and EARNEST both showed excellent response rates (>80%) for the WHO standard of care and indicated that a novel regimen of a boosted protease inhibitor with an integrase inhibitor had equal efficacy with no difference in toxicity. In EARNEST, a third arm consisting of induction with the combined protease and integrase inhibitor followed by protease inhibitor monotherapy maintenance was inferior and led to substantial (20%) protease inhibitor resistance. These studies confirm the validity of the current recommendations of WHO and point to a novel public health approach of using two new classes for second line when standard first-line therapy has failed, which avoids resistance genotyping. Notwithstanding, adherence must be stressed in those failing first-line treatments. Protease inhibitor monotherapy is not suitable for a public health approach in low- and middle-income countries.

  17. Measurements of weak conversion lines

    Feoktistov, A.I.; Frantsev, Yu.E.

    1979-01-01

    Described is a new methods for measuring weak conversion lines with the help of the β spectrometer of the π √ 2 type which permits to increase the reliability of the results obtained. According to this method the measurements were carried out by short series with the storage of the information obtained on the punched tape. The spectrometer magnetic field was stabilized during the measuring of the conversion spectra with the help of three nmr recorders. Instead of the dependence of the pulse calculation rate on the magnetic field value was measured the dependence of the calculation rate on the value of the voltage applied between the source and the spectrometer chamber. A short description of the automatic set-up for measuring conversion lines according to the method proposed is given. The main set-up elements are the voltage multiplexer timer, printer, scaler and the pulse analyzer. With the help of the above methods obtained is the K 1035, 8 keV 182 Ta line. It is obtained as a result of the composition of 96 measurement series. Each measurement time constitutes 640 s 12 points are taken on the line

  18. CERN Video News on line

    2003-01-01

    The latest CERN video news is on line. In this issue : an interview with the Director General and reports on the new home for the DELPHI barrel and the CERN firemen's spectacular training programme. There's also a vintage video news clip from 1954. See: www.cern.ch/video or Bulletin web page

  19. US line-ups outperform UK line-ups

    Seale-Carlisle, Travis M.; Mickes, Laura

    2016-01-01

    In the USA and the UK, many thousands of police suspects are identified by eyewitnesses every year. Unfortunately, many of those suspects are innocent, which becomes evident when they are exonerated by DNA testing, often after having been imprisoned for years. It is, therefore, imperative to use identification procedures that best enable eyewitnesses to discriminate innocent from guilty suspects. Although police investigators in both countries often administer line-up procedures, the details ...

  20. Eccentric vision : adverse interactions between line segments

    Andriessen, J.J.; Bouma, H.

    1976-01-01

    The paper deals with adverse interactions between line stimuli ineccentric vision. Bothcontrast thresholdandjust noticeable difference of slanthave been measured for a test line as a function of the distance from a number of surrounding lines. Test lines were either parallel or perpendicular to the

  1. Minimization over randomly selected lines

    Ismet Sahin

    2013-07-01

    Full Text Available This paper presents a population-based evolutionary optimization method for minimizing a given cost function. The mutation operator of this method selects randomly oriented lines in the cost function domain, constructs quadratic functions interpolating the cost function at three different points over each line, and uses extrema of the quadratics as mutated points. The crossover operator modifies each mutated point based on components of two points in population, instead of one point as is usually performed in other evolutionary algorithms. The stopping criterion of this method depends on the number of almost degenerate quadratics. We demonstrate that the proposed method with these mutation and crossover operations achieves faster and more robust convergence than the well-known Differential Evolution and Particle Swarm algorithms.

  2. On-line moisture analysis

    Cutmore, N G

    2002-01-01

    Measurement of the moisture content of iron ore has become a key issue for controlling moisture additions for dust suppression. In most cases moisture content is still determined by manual or automatic sampling of the ore stream, followed by conventional laboratory analysis by oven drying. Although this procedure enables the moisture content to be routinely monitored, it is too slow for control purposes. This has generated renewed interest in on-line techniques for the accurate and rapid measurement of moisture in iron ore on conveyors. Microwave transmission techniques have emerged over the past 40 years as the dominant technology for on-line measurement of moisture in bulk materials, including iron ores. Alternative technologies have their limitations. Infra-red analysers are used in a variety of process industries, but rely on the measurement of absorption by moisture in a very thin surface layer. Consequently such probes may be compromised by particle size effects and biased presentation of the bulk mater...

  3. Avoided intersections of nodal lines

    Monastra, Alejandro G; Smilansky, Uzy; Gnutzmann, Sven

    2003-01-01

    We consider real eigenfunctions of the Schroedinger operator in 2D. The nodal lines of separable systems form a regular grid, and the number of nodal crossings equals the number of nodal domains. In contrast, for wavefunctions of non-integrable systems nodal intersections are rare, and for random waves, the expected number of intersections in any finite area vanishes. However, nodal lines display characteristic avoided crossings which we study in this work. We define a measure for the avoidance range and compute its distribution for the random wave ensemble. We show that the avoidance range distribution of wavefunctions of chaotic systems follows the expected random wave distributions, whereas for wavefunctions of classically integrable but quantum non-separable systems, the distribution is quite different. Thus, the study of the avoidance distribution provides more support to the conjecture that nodal structures of chaotic systems are reproduced by the predictions of the random wave ensemble

  4. Line Creep in Paper Peeling

    Rosti J.

    2010-06-01

    Full Text Available We have studied experimentally the dynamics of the separation of a sheet of paper into two halves in a peeling configuration. The experimental setup consists of a peeling device, where a fracture front is driven along the plane of the paper, with a constant force. The theoretical picture is how an elastic line interacts with a random landscape of fracture toughness. We compare the results with theoretical simulations in several aspects. One recent finding concerns the autocorrelation function of the average front position. The data from the experiments produces so-called cusps or singularities in the correlation function, as predicted by the functional renormalization group theory for elastic lines. Comparisons with simulations with either a short range or a long range elastic kernel demonstrate that the latter agrees with the experimental observations, as expected.

  5. Efficient line matching with homography

    Shen, Yan; Dai, Yuxing; Zhu, Zhiliang

    2018-03-01

    In this paper, we propose a novel approach to line matching based on homography. The basic idea is to use cheaply obtainable matched points to boost the similarity between two images. Two types of homography method, which are estimated by direct linear transformation, transform images and extract their similar parts, laying a foundation for the use of optical flow tracking. The merit of the similarity is that rapid matching can be achieved by regionalizing line segments and local searching. For multiple homography estimation that can perform better than one global homography, we introduced the rank-one modification method of singular value decomposition to reduce the computation cost. The proposed approach results in point-to-point matches, which can be utilized with state-of-the-art point-match-based structures from motion (SfM) frameworks seamlessly. The outstanding performance and feasible robustness of our approach are demonstrated in this paper.

  6. Line strengths in WN stars

    Leep, E.M.

    1982-01-01

    The author has analyzed high-dispersion spectra of over 100 WN stars in the Galaxy and the Large Magellenic Cloud (LMC). Most of the spectra were obtained through 4-m telescopes (Conti, Leep, and Perry 1981). The measured strengths of the WN classification lines N III lambdalambda4634-41, N IV lambda4057, N V lambda4604 (Smith 1968) for stars on WN subtypes 2.5-8 are shown. The assignments of WN subtypes are based on visual estimates of ratios of line strengths according to the scheme of Smith (1968), except that stars appearing to be earlier than WN3 are classified as WN2 or WN2.5 as explained by van der Hucht et al. (1981) and by Conti, Leep and Perry (1981). (Auth.)

  7. Transversal Lines of the Debates

    Yolanda Onghena

    1998-12-01

    Full Text Available The Transversal Lines of the Debates gathers for publication the presentations of the scholars invited to the seminar. In the papers, Yolanda Onghena observes that the evolution from the cultural to the inter-cultural travels along four axes: the relations between cultureand society; the processes of change within identity-based dynamics; the representations of the Other; and, interculturality. Throughout the presentations and subsequent debates, whenever the different participants referred to aspects of the cultural identity problematic--”angst”, “obsession”, “deficit”, manipulation”, and others, these same participants in the Transversal Lines of the Debates also showed that, in certain areas, an optimistic viewpoint is not out of the question.

  8. Signal Transmission on Power Lines

    Dalby, Arne Brejning

    1997-01-01

    In the analysis of power-line networks over a large frequency span, the time-domain method used in programs like EMTP (Electromagnetic Time domain Program) can not be used. A more rigorous analysis method must be employed. The correct analysis method (assuming TEM-mode propagation) for multiple....... An approximate analysis method must be usedIn this paper it is shown that an eigenvectormatrix, that is the propagation modes, can be chosen almost arbitrarily if the frequency interval of interest lies below the frequency, where the line length is about 1/3 times the wavelength for the propagation mode...... with the lowest phase velocity. The propagation constants corresponding to the chosen eigenvector matrix (the quasi modes) are found iteratively, which is a much simpler procedure than finding the eigenvalues....

  9. Line integral on engineering mathematics

    Wiryanto, L. H.

    2018-01-01

    Definite integral is a basic material in studying mathematics. At the level of calculus, calculating of definite integral is based on fundamental theorem of calculus, related to anti-derivative, as the inverse operation of derivative. At the higher level such as engineering mathematics, the definite integral is used as one of the calculating tools of line integral. the purpose of this is to identify if there is a question related to line integral, we can use definite integral as one of the calculating experience. The conclusion of this research says that the teaching experience in introducing the relation between both integrals through the engineer way of thinking can motivate and improve students in understanding the material.

  10. On real quadric line complexes

    Krasnov, Vyacheslav A

    2010-01-01

    We describe the topological types of the real parts of the Kummer surfaces associated with real three-dimensional quadric line complexes. The topological type of the real part of such a surface is shown to depend on the number of real singular points: it is determined by the number of such points if any exist, and otherwise the real part of the Kummer surface is either empty or consists of one or two tori.

  11. About cosmic gamma ray lines

    Diehl, Roland

    2017-06-01

    Gamma ray lines from cosmic sources convey the action of nuclear reactions in cosmic sites and their impacts on astrophysical objects. Gamma rays at characteristic energies result from nuclear transitions following radioactive decays or high-energy collisions with excitation of nuclei. The gamma-ray line from the annihilation of positrons at 511 keV falls into the same energy window, although of different origin. We present here the concepts of cosmic gamma ray spectrometry and the corresponding instruments and missions, followed by a discussion of recent results and the challenges and open issues for the future. Among the lessons learned are the diffuse radioactive afterglow of massive-star nucleosynthesis in 26Al and 60Fe gamma rays, which is now being exploited towards the cycle of matter driven by massive stars and their supernovae; large interstellar cavities and superbubbles have been recognised to be of key importance here. Also, constraints on the complex processes making stars explode as either thermonuclear or core-collapse supernovae are being illuminated by gamma-ray lines, in this case from shortlived radioactivities from 56Ni and 44Ti decays. In particular, the three-dimensionality and asphericities that have recently been recognised as important are enlightened in different ways through such gamma-ray line spectroscopy. Finally, the distribution of positron annihilation gamma ray emission with its puzzling bulge-dominated intensity disctribution is measured through spatially-resolved spectra, which indicate that annihilation conditions may differ in different parts of our Galaxy. But it is now understood that a variety of sources may feed positrons into the interstellar medium, and their characteristics largely get lost during slowing down and propagation of positrons before annihilation; a recent microquasar flare was caught as an opportunity to see positrons annihilate at a source.

  12. Rapid reconnection of flux lines

    Samain, A.

    1982-01-01

    The rapid reconnection of flux lines in an incompressible fluid through a singular layer of the current density is discussed. It is shown that the liberated magnetic energy must partially appear in the form of plasma kinetic energy. A laminar structure of the flow is possible, but Alfven velocity must be achieved in eddies of growing size at the ends of the layer. The gross structure of the flow and the magnetic configuration may be obtained from variational principles. (author)

  13. Assembly delay line pulse generators

    CERN PhotoLab

    1971-01-01

    Assembly of six of the ten delay line pulse generators that will power the ten kicker magnet modules. One modulator part contains two pulse generators. Capacitors, inductances, and voltage dividers are in the oil tank on the left. Triggered high-pressure spark gap switches are on the platforms on the right. High voltage pulse cables to the kicker magnet emerge under the spark gaps. In the centre background are the assembled master gaps.

  14. Inductive line energy storage generator

    Choi, P [Ecole Polytechnique, Palaiseau (France). Laboratoire de Physique des Milieux Ionises

    1997-12-31

    The inductive energy storage (IES) generator has long been considered to be the most efficient system for energy usage in large pulsed power system at the MA level. A number of parameters govern the efficiency of energy transfer between the storage capacitors and the load, and the level of current deliverable to the load. For high power system, the energy storage capacitors are arranged as a Marx generator. The primary constraints are the inductances in the various parts of the circuit, in particular, the upstream inductance between the Marx and the POS, and the downstream inductance between the POS and the load. This paper deals with the effect of replacing part of the upstream inductance with a transmission line and introduces the new concept of an inductive line for energy storage (ILES). Extensive parametric scans were carried out on circuit simulations to investigate the effect of this upstream transmission line. A model was developed to explain the operation of the ILES design based on the data obtained. Comparison with an existing IES generator shows that the ILES design offers a significant improvement in the maximum current and hence energy delivered to an inductive load. (author). 5 figs., 1 ref.

  15. The laser integration line (LIL)

    Roussel, A.

    2006-01-01

    The laser integration line (LIL) was originally built to validate the technological choices made for the Megajoule laser that is being built nearby. The LIL is made up of a single line composed of 8 laser beams. Each laser beam consists of 4 main modules: 1) the impulse generator that delivers a 40 mm * 40 mm square cross section infrared laser beam (λ = 1053 nm); 2) the amplification module that involves 2 steps in power amplifying, the output signal is a laser impulse of 5 ns of time duration carrying an energy of 20.10 3 Joule at a wavelength of 1053 nm; 3) the transport line that leads 4 elementary laser beams through a system of 6 mirrors; and 4) the optical block of the focusing and frequency conversion system (SCF). The purpose of SCF is twofold, first to turn the 4 infrared elementary beams into 4 ultraviolet (λ = 351 nm) beams thanks to 2 KDP (potassium di-hydrogeno-phosphate) crystals, and secondly to merge and focus the 4 elementary beams on a unique spot of the target thanks to diffraction gratings with curved slits. (A.C.)

  16. Workshop on Radio Recombination Lines

    1980-01-01

    Since their first detection 15 years ago, radio recombination lines from several elements have been observed in a wide variety of objects including HII regions, planetary nebulae, molecular clouds, the diffuse interstellar medium, and recently, other galaxies. The observations span almost the entire range from 0.1 to 100 GHz, and employ both single­ djsh and aperture synthesis techniques. The theory of radio recombination lines has also advanced strongly, to the point where it is perhaps one of the best-understood in astro­ physics. In a parallel development, it has become possible over the last decade to study these same highly-excited atoms in the laboratory; this work provides further confirmation of the theoretical framework. However there has been continuing controversy over the astrophysical interpre­ tation of radio recombination line observations, especially regarding the role of stimulated emission. A workshop was held in Ottawa on 24-25 August, 1979, bringing together many of the active scientist...

  17. An Asian poverty line? Issues and options

    Klasen, Stephan

    2016-01-01

    Given Asia's record of rapid economic growth and the conceptual and empirical problems of the current international income poverty line ('dollar-a-day'), this paper discusses whether there is merit to develop an Asia-specific poverty line that addresses some of the shortcomings of the dollar-a-day line and additionally considers Asia's particular economic situation. We consider various ways of creating an Asia-specific poverty line, including an Asia-specific international income poverty line...

  18. A new mathematical formulation of the line-by-line method in case of weak line overlapping

    Ishov, Alexander G.; Krymova, Natalie V.

    1994-01-01

    A rigorous mathematical proof is presented for multiline representation on the equivalent width of a molecular band which consists in the general case of n overlapping spectral lines. The multiline representation includes a principal term and terms of minor significance. The principal term is the equivalent width of the molecular band consisting of the same n nonoverlapping spectral lines. The terms of minor significance take into consideration the overlapping of two, three and more spectral lines. They are small in case of the weak overlapping of spectral lines in the molecular band. The multiline representation can be easily generalized for optically inhomogeneous gas media and holds true for combinations of molecular bands. If the band lines overlap weakly the standard formulation of line-by-line method becomes too labor-consuming. In this case the multiline representation permits line-by-line calculations to be performed more effectively. Other useful properties of the multiline representation are pointed out.

  19. Mosaicism for r(X and der(Xdel(X(p11.23dup(X(p11.21p11.22 provides insight into the possible mechanism of rearrangement

    Fang Ping

    2008-07-01

    Full Text Available Abstract We report a patient with a unique and complex cytogenetic abnormality involving mosaicism for a small ring X and deleted Xp derivative chromosome with tandem duplication at the break point. The patient presented with failure to thrive, muscular hypotonia, and minor facial anatomic anomalies, all concerning for Turner syndrome. Brain MRI revealed mild thinning of the corpus callosum, an apparent decrease in ventricular white matter volume, and an asymmetric myelination pattern. Array comparative genome hybridization analysis revealed mosaicism for the X chromosome, deletion of the short arm of an X chromosome, and a duplication of chromosome region Xp11.21-p11.22. G-banded chromosome and FISH analyses revealed three abnormal cell lines: 46,X,der(Xdel(X(p11.23dup(X(p11.21p11.22/46,X,r(X(q11.1q13.1/45,X. The small ring X chromosome was estimated to be 5.2 Mb in size and encompassed the centromere and Xq pericentromeric region. X chromosome inactivation (XCI studies demonstrated a skewed pattern suggesting that the ring X remained active, likely contributing to the observed clinical features of brain dysmyelination. We hypothesize that a prezygotic asymmetric crossing over within a loop formed during meiosis in an X chromosome with a paracentric inversion resulted in an intermediate dicentric chromosome. An uneven breakage of the dicentric chromosome in the early postzygotic period might have resulted in the formation of one cell line with the X chromosome carrying a terminal deletion and pericentromeric duplication of the short arm and the second cell line with the X chromosome carrying a complete deletion of Xp. The cell line carrying the deletion of Xp could have then stabilized through self-circularization and formation of the ring X chromosome.

  20. Difference in membrane repair capacity between cancer cell lines and a normal cell line

    Frandsen, Stine Krog; McNeil, Anna K.; Novak, Ivana

    2016-01-01

    repair was investigated by disrupting the plasma membrane using laser followed by monitoring fluorescent dye entry over time in seven cancer cell lines, an immortalized cell line, and a normal primary cell line. The kinetics of repair in living cells can be directly recorded using this technique...... cancer cell lines (p immortalized cell line (p

  1. On line ultrasonic integrated backscatter

    Landini, L.; Picano, E.; Mazzarisi, A.; Santarelli, F.; Benassi, A.; De Pieri, G.

    1988-01-01

    A new equipment for on-line evaluation of index based on two-dimensional integrated backscatter from ultrasonic images is described. The new equipment is fully integrated into a B-mode ultrasonic apparatus which provides a simultaneous display of conventional information together with parameters of tissue characterization. The system has been tested with a backscattering model of microbubbles in polysaccharide solution, characterized by a physiological exponential time decay. An exponential fitting to the experimental data was performed which yielded r=0.95

  2. Integrated Glass Coating Manufacturing Line

    Brophy, Brenor [Enki Technology Inc., San Jose, CA (United States)

    2015-09-30

    This project aims to enable US module manufacturers to coat glass with Enki’s state of the art tunable functionalized AR coatings at the lowest possible cost and highest possible performance by encapsulating Enki’s coating process in an integrated tool that facilitates effective process improvement through metrology and data analysis for greater quality and performance while reducing footprint, operating and capital costs. The Phase 1 objective was a fully designed manufacturing line, including fully specified equipment ready for issue of purchase requisitions; a detailed economic justification based on market prices at the end of Phase 1 and projected manufacturing costs and a detailed deployment plan for the equipment.

  3. A contrario line segment detection

    von Gioi, Rafael Grompone

    2014-01-01

    The reliable detection of low-level image structures is an old and still challenging problem in computer vision. This?book leads a detailed tour through the LSD algorithm, a line segment detector designed to be fully automatic. Based on the a contrario framework, the algorithm works efficiently without the need of any parameter tuning. The design criteria are thoroughly explained and the algorithm's good and bad results are illustrated on real and synthetic images. The issues involved, as well as the strategies used, are common to many geometrical structure detection problems and some possible

  4. Radiative transfer in molecular lines

    Asensio Ramos, A.; Trujillo Bueno, J.; Cernicharo, J.

    2001-07-01

    The highly convergent iterative methods developed by Trujillo Bueno and Fabiani Bendicho (1995) for radiative transfer (RT) applications are generalized to spherical symmetry with velocity fields. These RT methods are based on Jacobi, Gauss-Seidel (GS), and SOR iteration and they form the basis of a new NLTE multilevel transfer code for atomic and molecular lines. The benchmark tests carried out so far are presented and discussed. The main aim is to develop a number of powerful RT tools for the theoretical interpretation of molecular spectra.

  5. Understanding broadband over power line

    Held, Gilbert

    2006-01-01

    Understanding Broadband over Power Line explores all aspects of the emerging technology that enables electric utilities to provide support for high-speed data communications via their power infrastructure. This book examines the two methods used to connect consumers and businesses to the Internet through the utility infrastructure: the existing electrical wiring of a home or office; and a wireless local area network (WLAN) access point.Written in a practical style that can be understood by network engineers and non-technologists alike, this volume offers tutorials on electric utility infrastru

  6. On-line nuclear orientation

    Krane, K.S.

    1990-01-01

    This grant has as its overall goal the pursuit of on-line nuclear orientation experiments for the purpose of eliciting details of nuclear structure from the decays of neutron-deficient nuclei, such as those produced by the Holifield Heavy-Ion Research Facility at Oak Ridge and extracted by the UNISOR Isotope Separator. This paper discusses: refrigerator development; the decay of 184 Au; the decay of 191 Hg to 191 Au; the decay of 189 Pt to 189 Ir; the decays of 109,111 Pd; the decay of 172 Er; and solid angle corrections

  7. The appearance of beam lines

    Carey, D.C.

    1993-05-01

    The combination of an existing graphics package with a large program like TRANSPORT has often resulted in considerable modification to the large program. Use of other graphics package has resulted in essentially having to repeat the work. This difficulty has been avoided in a modification of TRANSPORT which produce layouts of beam lines. Drawings of the reference trajectory and three-dimensional images of all magnets are made by the graphics package TOP DRAWER. Nothing specific to TOP DRAWER or any other graphics has been incorporated into TRANSPORT. If a user is with a different graphics package he or she can then begin usage of this alternate package essentially immediately

  8. On the relict recombination lines

    Bershtejn, I.N.; Bernshtejn, D.N.; Dubrovich, V.K.

    1977-01-01

    Accurate numerical calculation of intensities and profiles of hydrogen recombination lines of cosmological origin is made. Relie radiation distortions stipulated by recombination quantum release at the irrevocable recombination are investigated. Mean number calculation is given for guantums educing for one irrevocably-lost electron. The account is taken of the educed quantums interraction with matter. The main quantum-matter interrraction mechanisms are considered: electronic blow broadening; free-free, free-bound, bound-bound absorptions Recombination dynamics is investigated depending on hydrogen density and total density of all the matter kinds in the Universe

  9. Recent interstellar molecular line work

    Winnewisser, G.

    1975-01-01

    A summary of recent interstellar molecular line work is presented. Transitions of the following molecules have been detected in Sgr B2: Vinylcyanide, H 2 C 2 HCN, formic acid, HCOOH, dimethyl ether (CH 3 ) 2 O and isotopically labelled cyanoacetylene- 13 C,HC 13 CCN and HCC 13 CN. The data on cyanoacetylene give an upper limit to the abundance ratio 12 C/ 13 C of 36 +- 5. A short discussion of the interstellar chemistry leads to the conclusion that hydrocarbons such as acetylene, HCCH, ethylen, H 2 CCH 2 and ethane H 3 CCH 3 should be present in interstellar clouds. 13 refs

  10. Transient formation of forbidden lines

    Rosmej, F.B.; Rosmej, O.N.

    1996-01-01

    An explanation of anomalously long time scales in the transient formation of forbidden lines is proposed. The concept is based on a collisionally induced density dependence of the relaxation times of metastable level populations in transient plasma. Generalization leads to an incorporation of diffusion phenomena. We demonstrate this new concept for the simplest atomic system: the He-like isoelectronic sequence. A new interpretation of the observed long duration and anomalously high intensity of spin-forbidden emission in hot plasmas is given. (author)

  11. Walking at the drip line

    Bonaccorso, Angela

    2015-01-01

    Among exotic nuclei those at the drip line which are unstable against neutron emission are particularly interesting because they convey information on the nuclear force in the most extreme situations. Strictly speaking they are not ''nuclei'' but they exist thanks to long living resonances between a neutron and a bound ''core'' nucleus. Adding one more neutron they become bound and are called ''borromean''. Being particularly exotic they have attracted much attention in past years. One very challenging example is 13 Be whose level ordering has been discussed in a large number of papers in which it has been studied by transfer and fragmentation experiments, or it has been discussed theoretically. Although projectile fragmentation spectra show evident similarities, the interpretations of data all differ from each other. In this paper we argue that a way trough the problem could be to try to establish first, or at the same time, the quite elusive ''nature'' of the second s-state in the Beryllium isotopes with A=9-14. On the other hand there are other recent neutron removal experiments leading to nuclei unstable by one or more proton emissions, and thus somewhat mirror to borromean nuclei, performed with nuclei close to the proton drip line. It has been shown that by taking in coincidence all (charged) particles but the removed neutron, reconstructing the invariant mass and gating on the ground state peak, it is possible to obtain the longitudinal momentum distribution of the unbound ''core''. One can link it to the original wave function of the bound orbital and thus determine the initial neutron angular momentum from the shape of the distribution and the initial occupation probability from the absolute removal cross section. Then it is clear that modern experiments and theories are able to study unstable nuclei with the same degree of accuracy as stable nuclei. Such a

  12. Transient formation of forbidden lines

    Rosmej, F.B. [Bochum Univ., Ruhr (Germany). Inst. fuer Experimentalphysik V; Rosmej, O.N. [VNIIFTRI, Moscow Region (Russian Federation). MISDC

    1996-05-14

    An explanation of anomalously long time scales in the transient formation of forbidden lines is proposed. The concept is based on a collisionally induced density dependence of the relaxation times of metastable level populations in transient plasma. Generalization leads to an incorporation of diffusion phenomena. We demonstrate this new concept for the simplest atomic system: the He-like isoelectronic sequence. A new interpretation of the observed long duration and anomalously high intensity of spin-forbidden emission in hot plasmas is given. (author).

  13. service line analytics in the new era.

    Spence, Jay; Seargeant, Dan

    2015-08-01

    To succeed under the value-based business model, hospitals and health systems require effective service line analytics that combine inpatient and outpatient data and that incorporate quality metrics for evaluating clinical operations. When developing a framework for collection, analysis, and dissemination of service line data, healthcare organizations should focus on five key aspects of effective service line analytics: Updated service line definitions. Ability to analyze and trend service line net patient revenues by payment source. Access to accurate service line cost information across multiple dimensions with drill-through capabilities. Ability to redesign key reports based on changing requirements. Clear assignment of accountability.

  14. Line selection in celestial masers

    Middleton, M.S.

    1978-09-01

    The primary themes of this work concern the applicability of the Cook (1975) filter mechanism to line selection in hydroxyl masers, and the question of whether interstellar hydroxyl, water, and silicon monoxide masers are saturated. Whether the Cook filter is operative in celestial masers has not thus far been decided, even though it has been shown that such an effect might be occurring. The theory in its present form does not account for line broadening, nor have its consequences with regard to microwave maser emission from excited states of hydroxyl been explored. Both these topics are discussed and the findings are compared with the observations of NGC 6334A, a source which is interesting because of the strong evidence for Zeeman splitting which can be seen in some of its observed spectra. The question of whether interstellar masers are saturated has been much discussed, but a simple method for determining the state of saturation of observed masers does not exist. In particular, the importance of background radiation and of different cloud geometries on the state of saturation of interstellar masers up to now has not been fully appreciated. Both these topics are discussed. (author)

  15. Isotopic meteoric line for Colombia

    Rodriguez N, Cesar O

    2004-01-01

    Isotope analyses from representative rainfall samples taken from different areas in Colombia were processed to yield the meteoric line. Stable isotope composition in precipitation reflects the effects of temperature, altitude and of the continental site, being affected by different sources of atmospheric humidity over the Colombian territory. There is a seasonal variation in isotopic composition of precipitation with grater σ deviation during the rainy season and lower values in the dry season. In coastal areas the variation is smaller and is more pronounced than at continental stations. Correlation between altitude and isotope content led to equations, which indicate, on a regional level, a change in isotopic composition with altitude, of about 0.5 σ units per 200 m, for O 18 and 4 σ units per 200 m for H 2 . Such equations may be used to identify the original altitude of precipitation water, in hydrological surface and groundwater studies. Meteoric line and the concepts derived from the resulting equations presented in this paper may be applied to the interpretation of isotope analysis in future hydrological studies, particularly in areas without available data

  16. Separation of magnetic field lines

    Boozer, Allen H.

    2012-01-01

    The field lines of magnetic fields that depend on three spatial coordinates are shown to have a fundamentally different behavior from those that depend on two coordinates. Unlike two-coordinate cases, a flux tube in a magnetic field that depends on all three spatial coordinates that has a circular cross section at one location along the tube characteristically has a highly distorted cross section at other locations. In an ideal evolution of a magnetic field, the current densities typically increase. Crudely stated, if the current densities increase by a factor σ, the ratio of the long to the short distance across a cross section of a flux tube characteristically increases by e 2σ , and the ratio of the longer distance to the initial radius increases as e σ . Electron inertia prevents a plasma from isolating two magnetic field structures on a distance scale shorter than c/ω pe , which is about 10 cm in the solar corona, and reconnection must be triggered if σ becomes sufficiently large. The radius of the sun, R ⊙ =7×10 10 cm is about e 23 times larger, so when σ≳23, two lines separated by c/ω pe at one location can be separated by the full scale of any magnetic structures in the corona at another. The conditions for achieving a large exponentiation, σ, are derived, and the importance of exponentiation is discussed.

  17. Beam line design using G4BeamLine

    Dogan, Arda

    2014-01-01

    In Turkey in Ankara TAEK SANAEM Proton Accelerator Facility (PAF), there is a cyclotron which produces a focused intense 30 MeV proton beam and sends this beam to four different arms, three of which uses this beam to produce pharmaceutical medicine. The remaining one is spared for R&D purposes and the idea was to use these protons coming out from the fourth arm to use space radiation tests, which cannot be done in Turkey at the moment. However, according to SCC 25100 standards which is for 30 MeV protons, the beam coming out of cyclotron is too intense and focused to use for space radiation tests. Therefore, the main aim of my project is to design a beam line which will defocus the beam and reduce the flux so that the space radiation tests can be done according to the standards of SCC 25100.

  18. 32 CFR 644.7 - Acquisition lines.

    2010-07-01

    ... HANDBOOK Project Planning Civil Works § 644.7 Acquisition lines. (a) Tentative acquisition lines. As..., in accordance with sound real estate practices. Accordingly, fringe tracts will not be acquired until...

  19. Economic impact analysis of short line railroads.

    2014-10-01

    This research project assesses the economic role and impact of short line railroads in the state of Louisiana. While relatively small in : scope, with 11 operators and approximately 500 miles of track, short line railroads play a significant role in ...

  20. FB Line Basis for Interim Operation

    Shedrow, B.

    1998-01-01

    The safety analysis of the FB-Line Facility indicates that the operation of FB-Line to support the current mission does not present undue risk to the facility and co-located workers, general public, or the environment

  1. Basic Stand Alone Carrier Line Items PUF

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Carrier Line Items Public Use Files (PUF) with information from Medicare Carrier claims. The CMS BSA Carrier Line...

  2. Inversion of the OH 1720-MHz line

    Elitzur, M.

    1975-01-01

    It is shown that the OH 1720-MHz line can be strongly inverted by collisions which excite the rotation states. It is also argued that radiative pumps (of any wave length) can invert strongly only the 1612-MHz line. (author)

  3. State Wildlife Management Area Public Facilities - lines

    Minnesota Department of Natural Resources — This line theme contains facilities and features for WMAs that are best represented as lines. WMAs are part of the Minnesota state recreation system created to...

  4. 2008 TIGER/Line Nationwide Dataset

    California Natural Resource Agency — This dataset contains a nationwide build of the 2008 TIGER/Line datasets from the US Census Bureau downloaded in April 2009. The TIGER/Line Shapefiles are an extract...

  5. GOSAT-2014 methane spectral line list

    Nikitin, A.V.; Lyulin, O.M.; Mikhailenko, S.N.; Perevalov, V.I.; Filippov, N.N.; Grigoriev, I.M.; Morino, I.; Yoshida, Y.; Matsunaga, T.

    2015-01-01

    The updated methane spectral line list GOSAT-2014 for the 5550–6240 cm −1 region with the intensity cutoff of 5×10 –25 cm/molecule at 296 K is presented. The line list is based on the extensive measurements of the methane spectral line parameters performed at different temperatures and pressures of methane without and with buffer gases N 2 , O 2 and air. It contains the following spectral line parameters of about 12150 transitions: line position, line intensity, energy of lower state, air-induced and self-pressure-induced broadening and shift coefficients and temperature exponent of air-broadening coefficient. The accuracy of the line positions and intensities are considerably improved in comparison with the previous version GOSAT-2009. The improvement of the line list is done mainly due to the involving to the line position and intensity retrieval of six new spectra recorded with short path way (8.75 cm). The air-broadening and air-shift coefficients for the J-manifolds of the 2ν 3 (F 2 ) band are refitted using the new more precise values of the line positions and intensities. The line assignment is considerably extended. The lower state J-value was assigned to 6397 lines representing 94.4% of integrated intensity of the considering wavenumber region. The complete assignment was done for 2750 lines. - Highlights: • The upgrade of the GOSAT methane line list in the 5550–6240 cm −1 region is done. • 12,146 experimental methane line positions and intensities are retrieved. • 6376 lower energy levels for methane lines are determined

  6. Magnetic pulse sharpener and delay-line

    Li Jin; Dai Guangsen; Xia Liansheng

    2002-01-01

    This paper describes a method to achieve short rise time pulse which has been delayed with a delay-line and magnetic pulse sharpener. A delay-line and two shock-lines are designed to carry pulsed signal with a maximum voltage magnitude up to 80 kV. A pulse of High voltage with arise time of 48 ns at a level of 0.1%-0.9% were achieved, and the attenuation in the line is very small

  7. Illustrative Line Styles for Flow Visualization

    Everts, Maarten H.; Bekker, Hendrik; Roerdink, Jos B. T. M.; Isenberg, Tobias

    2011-01-01

    We present a flexible illustrative line style model for the visualization of streamline data. Our model partitions view-oriented line strips into parallel bands whose basic visual properties can be controlled independently. We thus extend previous line stylization techniques specifically for

  8. Flow Visualization using Illustrative Line Styles

    Everts, Maarten H.; Bekker, Hendrik; Roerdink, Jos B. T. M.; Isenberg, Tobias; Bekker, Paulus

    2011-01-01

    We present a flexible illustrative line style model for the visualization of streamline data. Our model partitions view- oriented line strips into parallel bands whose basic visual properties can be controlled independently. We thus extend previous line stylization techniques specifically for

  9. Microwave transmission-line impedance data

    Gunston, M A R

    1996-01-01

    A compendium of data for computing the characteristic impedance of transmission lines based on physical dimensions. Covers both conventional structures and unusual geometries, including coaxial, eccentric and elliptic coaxial, twin-wire, wire-above-ground, microstrip and derivatives, stripline, slabline and trough line. Also details numerous configurations of coupled lines.

  10. Moving droplets : The measurement of contact lines

    Poelma, C.; Franken, M.J.Z.; Kim, H.; Westerweel, J.

    2014-01-01

    Contact lines are the locations where a gas, liquid and a solid meet. From everyday experience we know that such contact lines can be mobile, for example in the case of a water droplet sliding over a glass surface. However, the continuum description of the flow towards or away from a contact line

  11. Formation of extremely narrow metallic lines

    Harris, E.P.; Keyes, R.W.

    1979-01-01

    A method for forming metal lines, particularly lines which are superconductive, involves delineating a pattern on a thin metal film on a substrate by masking techniques, ion implanting the metal film to a desired depth, removing the mask and etching away the unimplanted portion of the metal film to leave the line whose width is equal to the implanted depth. (U.K.)

  12. Unsplit bipolar pulse forming line

    Rhodes, Mark A [Pleasanton, CA

    2011-05-24

    A bipolar pulse forming transmission line module and system for linear induction accelerators having first, second, third, and fourth planar conductors which form a sequentially arranged interleaved stack having opposing first and second ends, with dielectric layers between the conductors. The first and second planar conductors are connected to each other at the first end, and the first and fourth planar conductors are connected to each other at the second end via a shorting plate. The third planar conductor is electrically connectable to a high voltage source, and an internal switch functions to short at the first end a high voltage from the third planar conductor to the fourth planar conductor to produce a bipolar pulse at the acceleration axis with a zero net time integral. Improved access to the switch is enabled by an aperture through the shorting plate and the proximity of the aperture to the switch.

  13. Beam line to S155

    1977-01-01

    The experiment S155 was designed by the Orsay (CSNM-CNRS) Collaboration to observe the properties of exotic light nuclei. It was installed in the PS neutrino tunnel. The photo shows a mass spectrometer (in the background) on line with the PS proton beam which arrives (bottom, right) from the fast extraction FE74. Roger Fergeau stands on the left. The alkaline isotopes produced in the carbon-uranium target heated at 2000°C were swiftly extracted, mass separated, and brought to a detector behind the shielding. Sodium 34 (11 protons and 23 neutrons) was observed and its half-life of only 5 ms was measured. The excited levels 2+ of Magnesium 30 and Magnesium 32 (Sodium descendants) were localised, and the magic number 20 was found to vanish. Thus, the discovery made earlier for Sodium 30 and Sodium 32, with the same apparatus, was confirmed. (See also photo 7706511.)

  14. Pipe Lines – External Corrosion

    Dan Babor

    2008-01-01

    Full Text Available Two areas of corrosion occur in pipe lines: corrosion from the medium carried inside the pipes; corrosion attack upon the outside of the pipes (underground corrosion. Electrolytic processes are also involved in underground corrosion. Here the moisture content of the soil acts as an electrolyte, and the ions required to conduct the current are supplied by water-soluble salts (chlorides, sulfates, etc. present in the soil. The nature and amount of these soluble materials can vary within a wide range, which is seen from the varying electrical conductivity and pH (varies between 3 and 10. Therefore the characteristics of a soil will be an important factor in under-ground corrosion.

  15. Magnetically insulated transmission line oscillator

    Bacon, L.D.; Ballard, W.P.; Clark, M.C.; Marder, B.M.

    1987-05-19

    A magnetically insulated transmission line oscillator employs self-generated magnetic fields to generate microwave energy. An anode of the oscillator includes slow-wave structures which are formed of a plurality of thin conductive vanes defining cavities therebetween, and a gap is formed between the anode and a cathode of the oscillator. In response to a pulsed voltage applied to the anode and cathode, self-generated magnetic fields are produced in a cross-field orientation with respect to the orientation of the electric field between the anode and the cathode. The cross-field magnetic fields insulate the flow of electrons in the gap and confine the flow of electrons within the gap. 11 figs.

  16. New support line for members

    AGU has recently established a new customer "support line"—solutions@agu.org—as the point of contact on AGU's staff for members and other individual constituents who have not been able to resolve issues or get questions answered promptly or to their satisfaction through customary channels.Over the past year, there have been many changes at AGU. Unfortunately—and perhaps as a result of these changes—communication with members and individual constituents has suffered. Some individuals report, for example, that e-mail messages are not answered to their satisfaction, or in a timely manner. Instructions on AGU's Web site are unclear in some areas. Problems related specifically to the transition to electronic publishing are cropping up.

  17. On-line moisture analysis

    Cutmore, N.G.; Mijak, D.G

    2002-01-01

    Measurement of the moisture content of iron ore has become a key issue for controlling moisture additions for dust suppression. In most cases moisture content is still determined by manual or automatic sampling of the ore stream, followed by conventional laboratory analysis by oven drying. Although this procedure enables the moisture content to be routinely monitored, it is too slow for control purposes. This has generated renewed interest in on-line techniques for the accurate and rapid measurement of moisture in iron ore on conveyors. Microwave transmission techniques have emerged over the past 40 years as the dominant technology for on-line measurement of moisture in bulk materials, including iron ores. Alternative technologies have their limitations. Infra-red analysers are used in a variety of process industries, but rely on the measurement of absorption by moisture in a very thin surface layer. Consequently such probes may be compromised by particle size effects and biased presentation of the bulk material. Nuclear-based analysers measure the total hydrogen content in the sample and do not differentiate between free and combined moisture. Such analysers may also be sensitive to material presentation and elemental composition. Very low frequency electromagnetic probes, such as capacitance or conductance probes, operate in the frequency region where the DC conductivity dominates much of the response, which is a function not only of moisture content but also of ionic composition and chemistry. These problems are overcome using microwave transmission techniques, which also have the following advantages, as a true bulk moisture analysis is obtained, because a high percentage of the bulk material is analysed; the moisture estimate is mostly insensitive to any biased presentation of moisture, for example due to stratification of bulk material with different moisture content and because no physical contact is made between the sensor and the bulk material. This is

  18. An urea, arginine and carnosine based cream (Ureadin Rx Db ISDIN shows greater efficacy in the treatment of severe xerosis of the feet in Type 2 diabetic patients in comparison with glycerol-based emollient cream. A randomized, assessor-blinded, controlled trial

    Federici Adalberto

    2012-09-01

    Full Text Available Abstract Background Xerosis is a common skin disorder frequently observed in diabetic patients. An effective hydration of foot skin in diabetics is a relevant preventive strategy in order to maintain a healthy foot. Urea is considered an effective hydrating and emollient topical product. The aim of the present study was to evaluate the efficacy of topical urea 5% with arginine and carnosine (Ureadin Rx Db, ISDIN Spain (UC in comparison with glycerol-based emollient topical product (Dexeryl, Pierre Fabre (EC, in Type 2 diabetic patients. Methods We assessed the effect of UC on skin hydration in a randomized, evaluator-blinded comparative study in 40 type II diabetic patients, aged 40–75 years, treated with UC or the comparator for 28 days with a twice-daily application. The principal outcomes were the Dryness Area Severity Index (DASI Score and the Visual Analogue Score (VAS for skin dryness evaluated at baseline and at the end of study period by an investigator unaware of treatment allocation. Results UC induced significantly greater hydration than EC with an 89% reduction in DASI score (from 1.6 to 0.2; p  Conclusion Application of urea 5%, arginine and carnosine cream increases skin hydration and alleviates the condition of skin dryness in Type 2 diabetic patients in comparison with a control glycerol-based emollient product. (Dutch Trials Register trial number 3328.

  19. Revised Line Profile Function for Hydrogenic Species

    Sapar A.

    2012-09-01

    Full Text Available Analytical series expansions for the hydrogenic spectral line profile functions are derived starting from the three single expressions, obtained by integrating twice the convolution of the Holtsmark, Lorentz and Doppler line profile functions. We get well converging series expansions for the line wings and centers by reducing the number of arguments in the profile function by one, introducing the module of the Holtsmark and Lorentz profiles as a new argument. In the intermediate part of the line, the parabolic cylinder functions expressed via the confluent hypergeometric series, are used. The multi-component Stark splitting of the hydrogenic spectral lines and the modeled stochastic electron transitions in the electric field of the adjacent ions generate wide Doppler plateaux at the line centers, with the characteristic widths estimated from the fit to the characteristic width of the Holtsmark profile. This additional Doppler broadening of the line profile function removes the central dip typical to the Holtsmark profile.

  20. Applying TPM on Production Line of Huanwei

    Zhai Yunkai

    2017-01-01

    The study based on the study and analysis of the TPM theory, based on my practice in the SMT2 production line of Victoria Electronics of Huanwei. Then it studied the promotion and implementation steps of TPM on SMT2 line. And it also introduced the improvement instance of SMT2 line. By contrasting the utilization of equipment on SMT2 line before and after the comprehensive of TPM, the necessity of implementing TPM is derived. For how to apply TPM on the production lines, and how to improve equipment comprehensive utilization, finish the order on time, provide high quality products to our customers, these are the main part of production line equipment management work. This article provides the reference for how to promote TPM on other production lines.

  1. Cluster Analysis of Maize Inbred Lines

    Jiban Shrestha

    2016-12-01

    Full Text Available The determination of diversity among inbred lines is important for heterosis breeding. Sixty maize inbred lines were evaluated for their eight agro morphological traits during winter season of 2011 to analyze their genetic diversity. Clustering was done by average linkage method. The inbred lines were grouped into six clusters. Inbred lines grouped into Clusters II had taller plants with maximum number of leaves. The cluster III was characterized with shorter plants with minimum number of leaves. The inbred lines categorized into cluster V had early flowering whereas the group into cluster VI had late flowering time. The inbred lines grouped into the cluster III were characterized by higher value of anthesis silking interval (ASI and those of cluster VI had lower value of ASI. These results showed that the inbred lines having widely divergent clusters can be utilized in hybrid breeding programme.

  2. Incentive-Compatible Robust Line Planning

    Bessas, Apostolos; Kontogiannis, Spyros; Zaroliagis, Christos

    The problem of robust line planning requests for a set of origin-destination paths (lines) along with their frequencies in an underlying railway network infrastructure, which are robust to fluctuations of real-time parameters of the solution. In this work, we investigate a variant of robust line planning stemming from recent regulations in the railway sector that introduce competition and free railway markets, and set up a new application scenario: there is a (potentially large) number of line operators that have their lines fixed and operate as competing entities issuing frequency requests, while the management of the infrastructure itself remains the responsibility of a single entity, the network operator. The line operators are typically unwilling to reveal their true incentives, while the network operator strives to ensure a fair (or socially optimal) usage of the infrastructure, e.g., by maximizing the (unknown to him) aggregate incentives of the line operators.

  3. Magnetic field line reconnection experiments

    Gekelman, W.; Stenzel, R.L.; Wild, N.

    1982-01-01

    A laboratory experiment concerned with the basic physics of magnetic field line reconnection is discussed. Stimulated by important processes in space plasmas and anomalous transport in fusion plasmas the work addresses the following topics: Dynamic magnetic fields in a high beta plasma, magnetic turbulence, plasma dynamics and energy transport. First, the formation of magnetic neutral sheets, tearing and island coalescence are shown. Nonstationary magnetic fluctuations are statistically evaluated displaying the correlation tensor in the #betta#-k domain for mode identification. Then, the plasma properties are analyzed with particular emphasis on transport processes. Although the classical fluid flow across the separatrix can be observed, the fluctuation processes strongly modify the plasma dynamics. Direct measurements of the fluid force density and ion acceleration indicate the presence of an anomalous scattering process characterized by an effective scattering tensor. Turbulence also enhances the plasma resistivity by one to two orders of magnitude. Measurements of the three-dimensional electron distribution function using a novel energy analyzer exhibit the formation of runaway electrons in the current sheet. Associated micro-instabilities are observed. Finally, a macroscopic disruptive instability of the current sheet is observed. Excess magnetic field energy is converted at a double layer into particle kinetic energy and randomized through beam-plasma instabilities. These laboratory results are compared with related observations in space and fusion plasmas. (Auth.)

  4. On-line data display

    Lang, Sherman Y. T.; Brooks, Martin; Gauthier, Marc; Wein, Marceli

    1993-05-01

    A data display system for embedded realtime systems has been developed for use as an operator's user interface and debugging tool. The motivation for development of the On-Line Data Display (ODD) have come from several sources. In particular the design reflects the needs of researchers developing an experimental mobile robot within our laboratory. A proliferation of specialized user interfaces revealed a need for a flexible communications and graphical data display system. At the same time the system had to be readily extensible for arbitrary graphical display formats which would be required for data visualization needs of the researchers. The system defines a communication protocol transmitting 'datagrams' between tasks executing on the realtime system and virtual devices displaying the data in a meaningful way on a graphical workstation. The communication protocol multiplexes logical channels on a single data stream. The current implementation consists of a server for the Harmony realtime operating system and an application written for the Macintosh computer. Flexibility requirements resulted in a highly modular server design, and a layered modular object- oriented design for the Macintosh part of the system. Users assign data types to specific channels at run time. Then devices are instantiated by the user and connected to channels to receive datagrams. The current suite of device types do not provide enough functionality for most users' specialized needs. Instead the system design allows the creation of new device types with modest programming effort. The protocol, design and use of the system are discussed.

  5. Isoeffect lines using TDF and CRE concepts

    Supe, S.J.; Sasane, J.B.; Gupta, M.K.; Supe, D.S.

    1979-01-01

    In most of the radiotherapy centres the treatment planning is based on isodose lines. Isoeffect lines are also being drawn based on the concepts of TDFs and CREs. A study has been made of whether the isoeffect lines based on the concepts of TDFs, CRes and the physical isodose lines are identical in all the treatment situations. Isoeffects lines for a few treatment schedules involving treatment of carcinoma of the bladder, treatment of cancer of the uterine cervix by combined intracavitary and external beam therapies and intracavitary therapy alone have been obtained and compared. The effect of treatment mode on the isoeffect lines has also been studied. It was found that the isodose curves and the isoeffect lines using the TDF and CRE concepts were not identical in all situations. Therefore, the ultimate treatment plans based on these isoeffect lines will not be exactly the same. The dependence of the isoeffect lines with the variation of the exponents of time and number of fractions used in the empirical relationship for NSD have also been investigated. Clinical trials have been initiated in the case of cancer of the bladder and cervix uterus based on the isodose curves and isoeffect lines using CRE and TDF concepts. (author)

  6. Line profile variations in selected Seyfert galaxies

    Kollatschny, W; Zetzl, M; Ulbrich, K

    2010-01-01

    Continua as well as the broad emission lines in Seyfert 1 galaxies vary in different galaxies with different amplitudes on typical timescales of days to years. We present the results of two independent variability campaigns taken with the Hobby-Eberly Telescope. We studied in detail the integrated line and continuum variations in the optical spectra of the narrow-line Seyfert galaxy Mrk 110 and the very broad-line Seyfert galaxy Mrk 926. The broad-line emitting region in Mrk 110 has radii of four to 33 light-days as a function of the ionization degree of the emission lines. The line-profile variations are matched by Keplerian disk models with some accretion disk wind. The broad-line region in Mrk 926 is very small showing an extension of two to three light-days only. We could detect a structure in the rms line-profiles as well as in the response of the line profile segments of Mrk 926 indicating the BLR is structured.

  7. Universal statistics of vortex lines.

    Nahum, Adam; Chalker, J T

    2012-03-01

    We study the vortex lines that are a feature of many random or disordered three-dimensional systems. These show universal statistical properties on long length scales, and geometrical phase transitions analogous to percolation transitions but in distinct universality classes. The field theories for these problems have not previously been identified, so that while many numerical studies have been performed, a framework for interpreting the results has been lacking. We provide such a framework with mappings to simple supersymmetric models. Our main focus is on vortices in short-range-correlated complex fields, which show a geometrical phase transition that we argue is described by the CP(k|k) model (essentially the CP(n-1) model in the replica limit n→1). This can be seen by mapping a lattice version of the problem to a lattice gauge theory. A related field theory with a noncompact gauge field, the 'NCCP(k|k) model', is a supersymmetric extension of the standard dual theory for the XY transition, and we show that XY duality gives another way to understand the appearance of field theories of this type. The supersymmetric descriptions yield results relevant, for example, to vortices in the XY model and in superfluids, to optical vortices, and to certain models of cosmic strings. A distinct but related field theory, the RP(2l|2l) model (or the RP(n-1) model in the limit n→1) describes the unoriented vortices that occur, for instance, in nematic liquid crystals. Finally, we show that in two dimensions, a lattice gauge theory analogous to that discussed in three dimensions gives a simple way to see the known relation between two-dimensional percolation and the CP(k|k) σ model with a θ term.

  8. Altering graphene line defect properties using chemistry

    Vasudevan, Smitha; White, Carter; Gunlycke, Daniel

    2012-02-01

    First-principles calculations are presented of a fundamental topological line defect in graphene that was observed and reported in Nature Nanotech. 5, 326 (2010). These calculations show that atoms and smaller molecules can bind covalently to the surface in the vicinity of the graphene line defect. It is also shown that the chemistry at the line defect has a strong effect on its electronic and magnetic properties, e.g. the ferromagnetically aligned moments along the line defect can be quenched by some adsorbates. The strong effect of the adsorbates on the line defect properties can be understood by examining how these adsorbates affect the boundary-localized states in the vicinity of the Fermi level. We also expect that the line defect chemistry will significantly affect the scattering properties of incident low-energy particles approaching it from graphene.

  9. Transmission of radioiodine through sampling lines

    Unrein, P.J.; Pelletier, C.A.; Cline, J.E.; Voilleque, P.G.

    1985-01-01

    An experimental program to measure radioiodine transmission through sampling lines is described. The transmission depends upon both deposition on and resuspension from the walls of the line. The deposition and resuspension processes are themselves controlled by the length, diameter, and material of the line and the conditions under which it is operated. The operating conditions under study are sampling flow rate, temperature and relative humidity. Measurement results have been interpreted in terms of a four-compartment model of radioiodine deposition and resuspension. The model is applied to each of twenty or more segments of the line. Experimental measurements of short-term transmission fractions and the deposition velocities derived from them are presented for six lines. Data on resuspension rates for the same lines were obtained and are also discussed

  10. Nuclear gamma ray lines from supernovae

    Jardim, J.O.D.

    1980-01-01

    From theoretical considerations of the behaviour of gamma ray line fluxes occurring after a supernova explosion, the 1.156 and 0.847 MeV lines are seen to be the most likely to be observed. The 1.156 MeV line has been previously observed by other investigators. Observations of the 0.847 MeV line, and 1.332, 1.173 and 0.059 MeV lines using a Ge(Li) telescope aboard a stratospheric balloon which was flown in Brazil in 1977 are reported. The observation using a NaI(Tl) detector of a line in the energy interval 1.5 - 1.6 MeV, which may be due to 0 18 (p,p') 0 18 sup (*) reaction is also reported. (Author) [pt

  11. Modification of beam lines at VEC

    Shoor, Bivas; Chakraborty, P S; Mallik, C; Bhandari, R K [Variable Energy Cyclotron Centre, Calcutta (India)

    1997-12-01

    From the experience of light ion beam transportation through the Variable Energy Cyclotron beam line, it was observed that the beam line performance has to be improved in view of heavy ion acceleration program at the centre. The aim of this work was to study the feasibility of reducing the number of operational parameters without hampering the beam transmission and at the same time, to improve the vacuum of the beam line by reducing the hardware 2 refs., 1 fig.

  12. Numerical Calculation of Overhead Power Lines Dynamics

    Gogola Roman

    2016-11-01

    Full Text Available This paper contains results of transient analysis of airflow around the ACSR power line cross-section in unsymmetric multi-span. The forces applied to the power line are obtained from CFD simulations, where the wind induced vibration is studied. Effect of these forces to the maximal displacement of the power line and the maximal mechanical forces in the points of attachment are studied and evaluated.

  13. Ghost lines in Moessbauer relaxation spectra

    Price, D.C.

    1985-01-01

    The appearance in Moessbauer relaxation spectra of 'ghost' lines, which are narrow lines that do not correspond to transitions between real hyperfine energy levels of the resonant system, is examined. It is shown that in many cases of interest, the appearance of these 'ghost' lines can be interpreted in terms of the relaxational averaging of one or more of the static interactions of the ion. (orig.)

  14. Response analysis on nonuniform transmission line

    Cvetković Zlata

    2005-01-01

    Full Text Available Transients on a loss less exponential transmission line with a pure resistance load are presented in this paper. The approach is based on the two-port presentation of the transmission line. Using Picard-Carson's method the transmission line equations are solved. The relationship between source voltage and the load voltage in s-domain is derived. All the results are plotted using program package Mathematica 3.0.

  15. A Product Line Enhanced Unified Process

    Zhang, Weishan; Kunz, Thomas

    2006-01-01

    The Unified Process facilitates reuse for a single system, but falls short handling multiple similar products. In this paper we present an enhanced Unified Process, called UPEPL, integrating the product line technology in order to alleviate this problem. In UPEPL, the product line related activit...... activities are added and could be conducted side by side with other classical UP activities. In this way both the advantages of Unified Process and software product lines could co-exist in UPEPL. We show how to use UPEPL with an industrial mobile device product line in our case study....

  16. Pipe line construction for reactor containment buildings

    Aoki, Masataka; Yoshinaga, Toshiaki

    1978-01-01

    Purpose: To prevent the missile phenomenon caused by broken fragments due to pipe whip phenomenon in a portion of pipe lines connected to a reactor containment from prevailing to other portions. Constitution: Various pipe lines connected to the pressure vessel are disposed at the outside of the containments and they are surrounded with a plurality of protection partition walls respectively independent from each other. This can eliminate the effect of missile phenomena upon pipe rupture from prevailing to the pipe lines and instruments. Furthermore this can afford sufficient spaces for the pipe lines, as well as for earthquake-proof supports. (Horiuchi, T.)

  17. Earthquake free design of pipe lines

    Kurihara, Chizuko; Sakurai, Akio

    1974-01-01

    Long structures such as cooling sea water pipe lines of nuclear power plants have a wide range of extent along the ground surface, and are incurred by not only the inertia forces but also forces due to ground deformations or the seismic wave propagation during earthquakes. Since previous reports indicated the earthquake free design of underground pipe lines, it is discussed in this report on behaviors of pipe lines on the ground during earthquakes and is proposed the aseismic design of pipe lines considering the effects of both inertia forces and ground deformations. (author)

  18. Signal integrity analysis on discontinuous microstrip line

    Qiao, Qingyang; Dai, Yawen; Chen, Zipeng

    2013-01-01

    In high speed PCB design, microstirp lines were used to control the impedance, however, the discontinuous microstrip line can cause signal integrity problems. In this paper, we use the transmission line theory to study the characteristics of microstrip lines. Research results indicate that the discontinuity such as truncation, gap and size change result in the problems such as radiation, reflection, delay and ground bounce. We change the discontinuities to distributed parameter circuits, analysed the steady-state response and transient response and the phase delay. The transient response cause radiation and voltage jump.

  19. Magnetization of topological line-node semimetals

    Mikitik, G. P.; Sharlai, Yu. V.

    2018-02-01

    Using an approximate expression for the Landau levels of the electrons located near a nodal line of a topological line-node semimetal, we obtain formulas for the magnetization of this semimetal at an arbitrary shape of its line. It is also shown that the dependence of the chemical potential on the magnetic field can be strong in these materials, and this dependence can essentially influence the de Haas-van Alphen oscillations. The obtained results are applied to the rhombohedral graphite, which is one of the line-node semimetals. For this material, we find temperature and magnetic field dependencies of its magnetic susceptibility.

  20. Transmission Line Security Monitor: Final Report

    John Svoboda

    2011-04-01

    The Electric Power Transmission Line Security Monitor System Operational Test is a project funded by the Technical Support Working Group (TSWG). TSWG operates under the Combating Terrorism Technical Support Office that functions under the Department of Defense. The Transmission Line Security Monitor System is based on technology developed by Idaho National Laboratory. The technology provides a means for real-time monitoring of physical threats and/or damage to electrical transmission line towers and conductors as well as providing operational parameters to transmission line operators to optimize transmission line operation. The end use is for monitoring long stretches of transmission lines that deliver electrical power from remote generating stations to cities and industry. These transmission lines are generally located in remote transmission line corridors where security infrastructure may not exist. Security and operational sensors in the sensor platform on the conductors take power from the transmission line and relay security and operational information to operations personnel hundreds of miles away without relying on existing infrastructure. Initiated on May 25, 2007, this project resulted in pre-production units tested in realistic operational environments during 2010. A technology licensee, Lindsey Manufacturing of Azusa California, is assisting in design, testing, and ultimately production. The platform was originally designed for a security monitoring mission, but it has been enhanced to include important operational features desired by electrical utilities.

  1. Iron forbidden lines in tokamak discharges

    Suckewer, S.; Hinnov, E.

    1979-03-01

    Several spectrum lines from forbidden transitions in the ground configurations of highly ionized atoms have been observed in the PLT tokamak discharges. Such lines allow localized observations, in the high-temperature regions of the plasma, of ion-temperatures, plasma motions, and spatial distributions of ions. Measured absolute intensities of the forbidden lines have been compared with simultaneous observations of the ion resonance lines and with model calculations in order to deduce the mechanism of level populaions by means of electron collisions and radiative transitions

  2. Iron forbidden lines in tokamak discharges

    Suckewer, S.; Hinnov, E.

    1979-03-01

    Several spectrum lines from forbidden transitions in the ground configurations of highly ionized atoms have been observed in the PLT tokamak discharges. Such lines allow localized observations, in the high-temperature regions of the plasma, of ion-temperatures, plasma motions, and spatial distributions of ions. Measured absolute intensities of the forbidden lines have been compared with simultaneous observations of the ion resonance lines and with model calculations in order to deduce the mechanism of level populaions by means of electron collisions and radiative transitions.

  3. Plasma line observations in the auroral oval

    Valladares, C.E.; Kelley, M.C.; Vickrey, J.F.

    1988-01-01

    We report here a series of experiments conducted at the Sondre Stromfjord incoherent scatter radar, aimed at detected enhanced plasma lines associated with midnight sector auroral arcs. Using different receivers, we detected both ion and plasma lines simultaneously. The plasma line signal was recorded with the use of a filter bank of eight frequencies. Plasma lines were found to originate mainly from the topside of the particle-produced E layer. The enhanced plasma lines are sometimes a factor of 100 times larger than the thermal level. Our data show a rapid decay of the plasma lines, however. In some cases, only a 30-s integration time was needed in order to unambiguously detect both upshifted and downshifted lines. The level of the plasma lines reaches values of, for the larger cases, up to 40 0 K above the noise temperature. These are considerably higher than results from prior auroral zone plasma line experiments. In situ observations of enhanced plasma waves in this same region are reported in a companion paper. copyright American Geophysical Union 1988

  4. Stability of the LHC transfer lines

    Kain, V; Bartmann, W; Bracco, C; Goddard, B; Meddahi, M; Uythoven, J; Wenninger, J

    2011-01-01

    The LHC is filled from the SPS through two 3 km transfer lines. The injected beam parameters need to be well under control for luminosity performance, machine protection and operational efficiency. Small fractions of beam loss on the transfer line collimation system create showers which can trigger the sensitive LHC beam loss monitor system nearby and cause a beam abort during filling. The stability of the transfer line trajectory through the collimators is particularly critical in this respect. This paper will report on the transfer line trajectory stability during the proton run in 2011, correlations with injection losses, correction frequency and the most likely sources for the observed oscillations.

  5. Tubular lining material for pipelines having bends

    Moringa, A.; Sakaguchi, Y.; Hyodo, M.; Yagi, I.

    1987-03-24

    A tubular lining material for pipelines having bends or curved portions comprises a tubular textile jacket made of warps and wefts woven in a tubular form overlaid with a coating of a flexible synthetic resin. It is applicable onto the inner surface of a pipeline having bends or curved portions in such manner that the tubular lining material with a binder onto the inner surface thereof is inserted into the pipeline and allowed to advance within the pipeline, with or without the aid of a leading rope-like elongated element, while turning the tubular lining material inside out under fluid pressure. In this manner the tubular lining material is applied onto the inner surface of the pipeline with the binder being interposed between the pipeline and the tubular lining material. The lining material is characterized in that a part of all of the warps are comprised of an elastic yarn around which, over the full length thereof, a synthetic fiber yarn or yarns have been left-and/or right-handedly coiled. This tubular lining material is particularly suitable for lining a pipeline having an inner diameter of 25-200 mm and a plurality of bends, such as gas service pipelines or house pipelines, without occurrence of wrinkles in the lining material in a bend.

  6. UV line emission of symbiotic stars

    Nussbaumer, H.

    1982-01-01

    General characteristics of emission line spectra from symbiotic stars are outlined. Data from some special line ratios in the 1000 A - 3000 A range, and others connecting the visual and the far UV lines are presented, and their application to symbiotic stars is discussed. Integrated fractional abundances for ions easily observed in the far UV are given to facilitate abundance determinations for nebular conditions. It is found that the physical conditions of the regions emitting the emission line spectra differ considerably among different symbiotic stars. (Auth.)

  7. Asymmetries of the solar Ca II lines

    Heasley, J.N.

    1975-01-01

    A theoretical study of the influence of propagating acoustic pulses in the solar chromosphere upon the line profiles of the Ca II resonance and infrared triplet lines has been made. The major objective has been to explain the observed asymmetries seen in the cores of the H and K lines and to predict the temporal behavior of the infrared lines caused by passing acoustic or shock pulses. The velocities in the pulses, calculated from weak shock theory, have been included consistently in the non-LTE calculations. The results of the calculations show that these lines are very sensitive to perturbations in the background atmosphere caused by the pulses. Only minor changes in the line shapes result from including the velocities consistently in the line source function calculations. The qualitative changes in the line profiles vary markedly with the strength of the shock pulses. The observed differences in the K line profiles seen on the quiet Sun can be explained in terms of a spectrum of pulses with different wavelengths and initial amplitudes in the photosphere. (Auth.)

  8. Displacement of location in illusory line motion.

    Hubbard, Timothy L; Ruppel, Susan E

    2013-05-01

    Six experiments examined displacement in memory for the location of the line in illusory line motion (ILM; appearance or disappearance of a stationary cue is followed by appearance of a stationary line that is presented all at once, but the stationary line is perceived to "unfold" or "be drawn" from the end closest to the cue to the end most distant from the cue). If ILM was induced by having a single cue appear, then memory for the location of the line was displaced toward the cue, and displacement was larger if the line was closer to the cue. If ILM was induced by having one of two previously visible cues vanish, then memory for the location of the line was displaced away from the cue that vanished. In general, the magnitude of displacement increased and then decreased as retention interval increased from 50 to 250 ms and from 250 to 450 ms, respectively. Displacement of the line (a) is consistent with a combination of a spatial averaging of the locations of the cue and the line with a relatively weaker dynamic in the direction of illusory motion, (b) might be implemented in a spreading activation network similar to networks previously suggested to implement displacement resulting from implied or apparent motion, and (c) provides constraints and challenges for theories of ILM.

  9. Development of a Handheld Line Information Reader and Generator for Efficient Management of Optical Communication Lines.

    Lee, Jaeyul; Kwon, Hyungwoo; Song, Jaewon; Jeon, Mansik; Kim, Jeehyun

    2017-08-24

    A handheld line information reader and a line information generator were developed for the efficient management of optical communication lines. The line information reader consists of a photo diode, trans-impedance amplifier, voltage amplifier, microcontroller unit, display panel, and communication modules. The line information generator consists of a laser diode, laser driving circuits, microcontroller unit, and communication modules. The line information reader can detect the optical radiation field of the test line by bending the optical fiber. To enhance the sensitivity of the line information reader, an additional lens was used with a focal length of 4.51 mm. Moreover, the simulation results obtained through BeamPROP ® software from Synopsys, Inc. demonstrated a stronger optical radiation field of the fiber due to a longer transmission wavelength and larger bending angle of the fiber. Therefore, the developed devices can be considered as useful tools for the efficient management of optical communication lines.

  10. Theoretical Atomic Physics code development IV: LINES, A code for computing atomic line spectra

    Abdallah, J. Jr.; Clark, R.E.H.

    1988-12-01

    A new computer program, LINES, has been developed for simulating atomic line emission and absorption spectra using the accurate fine structure energy levels and transition strengths calculated by the (CATS) Cowan Atomic Structure code. Population distributions for the ion stages are obtained in LINES by using the Local Thermodynamic Equilibrium (LTE) model. LINES is also useful for displaying the pertinent atomic data generated by CATS. This report describes the use of LINES. Both CATS and LINES are part of the Theoretical Atomic PhysicS (TAPS) code development effort at Los Alamos. 11 refs., 9 figs., 1 tab

  11. Conceptual design for transmission line inspection robot

    Jalal, M F Abdul; Sahari, K S Mohamed; Anuar, A; Arshad, A D Mohd; Idris, M S

    2013-01-01

    Power transmission line is used for power distribution purposes due to their cost effective measure compared to underlying cable. However, prolonged exposure to natural weather may cause fatigue stress to the lines as well as induce material failure. Therefore, periodical line inspection is considered uttermost important as a preventive measure to avoid power outage. However, transmission line inspection has always been a high risk and expensive work. Hazardous works that may harm operator as well as routine that requires precise handling can be performed by robots. Various types of robots have been designed and developed for line inspection but only perform well on a straight and continuous line. As these robots encounter an obstacle during the inspection, then the real problem in terms of robot stability and smooth operation arises. In this paper, conceptual design and evaluation for transmission line inspection robot is presented. The inspection robot mobile robot must be able to bypass or avoid obstacles as it travels along the power transmission line.

  12. Multiple gamma lines from semi-annihilation

    D'Eramo, Francesco; McCullough, Matthew; Thaler, Jesse

    2013-01-01

    Hints in the Fermi data for a 130 GeV gamma line from the galactic center have ignited interest in potential gamma line signatures of dark matter. Explanations of this line based on dark matter annihilation face a parametric tension since they often rely on large enhancements of loop-suppressed cross sections. In this paper, we pursue an alternative possibility that dark matter gamma lines could arise from ''semi-annihilation'' among multiple dark sector states. The semi-annihilation reaction ψ i ψ j → ψ k γ with a single final state photon is typically enhanced relative to ordinary annihilation ψ i ψ-bar i → γγ into photon pairs. Semi-annihilation allows for a wide range of dark matter masses compared to the fixed mass value required by annihilation, opening the possibility to explain potential dark matter signatures at higher energies. The most striking prediction of semi-annihilation is the presence of multiple gamma lines, with as many as order N 3 lines possible for N dark sector states, allowing for dark sector spectroscopy. A smoking gun signature arises in the simplest case of degenerate dark matter, where a strong semi-annihilation line at 130 GeV would be accompanied by a weaker annihilation line at 173 GeV. As a proof of principle, we construct two explicit models of dark matter semi-annihilation, one based on non-Abelian vector dark matter and the other based on retrofitting Rayleigh dark matter

  13. Line-mode browser development days

    Anna Pantelia

    2013-01-01

    Twelve talented web developers have travelled to CERN from all over the world to recreate a piece of web history: the line-mode browser. See the line-mode browser simulator that they created here. Read more about the birth of the web here.

  14. Modeling operational behavior of a disassembly line

    Kizilkaya, Elif A.; Gupta, Surendra M.

    2004-12-01

    In this paper we present a dynamic kanban (pull) system specifically developed for disassembly lines. This type of kanban system is much more complex than the traditional kanban system used in assembly lines. For instance, unlike the assembly line where the external demand occurs only at the last station, the demands in the disassembly case also occur at any of the intermittent stations. The reason is that as a product moves on the disassembly line, various parts are disassembled at every station and accumulated at that station. Therefore, there are as many demand sources as there are number of parts. We consider a case example involving the end-of-life products. Based on the precedence relationships and other criteria such as hazardous properties of the parts, we balance the disassembly line. The results of the disassembly line-balancing problem (DLBP) are used as input to the proposed dynamic kanban system for disassembly line (DKSDL). We compare the performance of the DKSDL to the modified kanban system for disassembly line (MKSDL), which was previously introduced by the authors. We show, via simulation, that the DKSDL is far superior to MKSDL considered.

  15. Transgenic cassava lines carrying heterologous alternative oxidase ...

    Afuape

    2013-07-03

    Jul 3, 2013 ... production of flowers, apomixis (Nassar et al., 2000; ... In order to increase the stress tolerance capacity of ... stress-related procedure due to the activities of auxin ... the evaluation of the transgenic lines for rate of OES .... Some transgenic lines carrying the 35S-AOX fragment amplified using 35S303F1 and.

  16. 25 CFR 226.33 - Line drilling.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Line drilling. 226.33 Section 226.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF OSAGE RESERVATION LANDS FOR OIL AND GAS MINING Requirements of Lessees § 226.33 Line drilling. Lessee shall not drill within 300 feet...

  17. Properties of 3-dimensional line location models

    Brimberg, Jack; Juel, Henrik; Schöbel, Anita

    2002-01-01

    We consider the problem of locating a line with respect to some existing facilities in 3-dimensional space, such that the sum of weighted distances between the line and the facilities is minimized. Measuring distance using the l\\_p norm is discussed, along with the special cases of Euclidean...

  18. Isoeffect lines using TDF and CRE concepts

    Supe, S.J.; Sasane, J.B.; Supe, D.S.

    1980-01-01

    Isoeffect lines based on Ellis' Nominal Standard Dose concept, Orton's Time Dose and Fractionation Factor (TDF) concept, and Kirk et al's Cumulative Radiation Effect (CRE) concept give differing results of treatment planning. Experience with isoeffect lines based on the above concepts in planning in case of radiotherapy for carcinoma of bladder and carcinoma of uterine cervix is narrated. (M.G.B.)

  19. Factored Facade Acquisition using Symmetric Line Arrangements

    Ceylan, Duygu; Mitra, Niloy J.; Li, Hao; Weise, Thibaut; Pauly, Mark

    2012-01-01

    We introduce a novel framework for image-based 3D reconstruction of urban buildings based on symmetry priors. Starting from image-level edges, we generate a sparse and approximate set of consistent 3D lines. These lines are then used

  20. Acoustic Wave Propagation in Pressure Sense Lines

    Vitarius, Patrick; Gregory, Don A.; Wiley, John; Korman, Valentin

    2003-01-01

    Sense lines are used in pressure measurements to passively transmit information from hostile environments to areas where transducers can be used. The transfer function of a sense line can be used to obtain information about the measured environment from the protected sensor. Several properties of this transfer function are examined, including frequency dependence, Helmholtz resonance, and time of flight delay.

  1. Composite Based EHV AC Overhead Transmission Lines

    Sørensen, Thomas Kjærsgaard

    and analysed with regard to the possibilities, limitations and risks widespread application of composite materials on EHV AC overhead transmission lines may present. To form the basis for evaluation of the useability of composite materials, dierent overhead line projects aimed at reducing the environmental...

  2. Autoionization spectral line shapes in dense plasmas

    Rosmej, F.B.; Hoffmann, D.H.H.; Faenov, A.Ya.; Pikuz, T.A.; Suess, W.; Geissel, M.

    2001-01-01

    The distortion of resonance line shapes due to the accumulation of a large number of satellite transitions is discovered by means of X-ray optical methods with simultaneous high spectral (λ/δλ≅8000) and spatial resolution (δx≅7 μm). Disappearance of the He α resonance line emission near the target surface is observed while Rydberg satellite intensity accumulates near the resonance line position. He β and He γ resonance line shapes are also shown to be seriously affected by opacity, higher-order line emissions from autoionizing states and inhomogeneous spatial emission. Opposite to resonance line emissions the He β satellites originate only from a very narrow spatial interval. New temperature and density diagnostics employing the 1s2131' and 1s3131'-satellites are developed. Moreover, even-J components of the satellite line emissions were resolved in the present high resolution experiments. Line transitions from the autoionizing states 1s2131' are therefore also proposed for space resolved Stark broadening analysis and local high density probing. Theorists are encouraged to provide accurate Stark broadening data for the transitions 1s2131 ' →1s 2 21+hv

  3. Power flow studies of magnetically insulated lines

    McDaniel, D.H.; Poukey, J.W.; Bergeron, K.D.; VanDevender, J.P.; Johnson, D.L.

    1977-01-01

    The designs for relativistic electron beam accelerators with power levels of 20 to 100 TW are greatly restricted by the inductance of a single diode of reasonable size. This fact leads to modular designs of very large accelerators. One concept uses several small insulators at a large radius arranged around the accelerator center. The total effective inductance is then low, but the energy must then be transported by self-magnetic insulated vacuum lines to the target volume. A triplate vacuum line configuration eases many mechanical support problems and allows more A-K gaps or feeds to be packaged around a given radius. This type of vacuum transmission line was chosen for initial experiments at Sandia. The experiments were conducted on the MITE (Magnetically Insulated Transmission Experiment) accelerator. The water pulse forming lines are connected to a vacuum triplate line through a conventional stacked insulator. Diagnostics on the experiment consisted of: (1) input V; (2) input I; (3) I monitors at the input, middle, and output of both the center conductor and ground plane of the transmission line; (4) magnetic energy analyzer to view peak electron energy in the A-K gap; (5) calorimetry; and (6) Faraday cups to look at electron current flowing across the transmission line. The main goal of the experiment is to obtain input impedance of the transmission line as a function of voltage and to measure electron loss currents. These measurements are compared to theoretical models for the input impedance and energy losses

  4. Angular assymetries in a shielded pair line

    Fanchiotti, H.; Garcia Canal, C.A.; Vucetich, H.

    1979-01-01

    The capacitance matrix and surface charge density distribution of an unbalanced pair line with both longitudinal and balanced excitations is presented. In particular the case in which the axes of the inner wires are not restricted to lie on a line through the axis of the shield is discussed

  5. Line radiative transfer and statistical equilibrium

    Kamp, Inga

    Atomic and molecular line emission from protoplanetary disks contains key information of their detailed physical and chemical structures. To unravel those structures, we need to understand line radiative transfer in dusty media and the statistical equilibrium, especially of molecules. I describe

  6. The LHCb VELO analogue transmission line

    Bay, A.; Borel, J.; Buytaert, J.; De Laere, S.; Frei, R.; Haefeli, G.; Koppenburg, P.; Locatelli, L.; Schneider, O.; Zehr, F.

    2010-01-01

    The Vertex Locator is one of the most important sub-detectors of the LHCb experiment, which is devoted to B physics. The signals from the silicon strip sensors are multiplexed at 40 MHz and transported by 60 m copper lines to the counting stations placed in a radiation safe area. This paper describes the development of this long transmission line and its performance.

  7. Some aspects of VUV beam line design

    Gaupp, A.; Peatman, W.

    1997-01-01

    Some aspects of the design and usage of vacuum ultraviolet beam lines are discussed. Fermat's principle for imaging is introduced and applied to grating monochromators. Some typical vacuum ultraviolet beam lines are presented, and some further topics believed to be of importance today and in the future are mentioned. (author)

  8. Veterans Crisis Line: 1-800-273-8255

    Veterans Crisis Line Skip to Main Content SuicidePreventionLifeline.org Get Help Materials Get Involved Crisis Centers About Be There ... Line FAQs Veteran Suicide Welcome to the Veterans Crisis Line Website The Veterans Crisis Line connects Veterans ...

  9. Response function of a moving contact line

    Perrin, H.; Belardinelli, D.; Sbragaglia, M.; Andreotti, B.

    2018-04-01

    The hydrodynamics of a liquid-vapor interface in contact with a heterogeneous surface is largely impacted by the presence of defects at the smaller scales. Such defects introduce morphological disturbances on the contact line and ultimately determine the force exerted on the wedge of liquid in contact with the surface. From the mathematical point of view, defects introduce perturbation modes, whose space-time evolution is governed by the interfacial hydrodynamic equations of the contact line. In this paper we derive the response function of the contact line to such generic perturbations. The contact line response may be used to design simplified one-dimensional time-dependent models accounting for the complexity of interfacial flows coupled to nanoscale defects, yet offering a more tractable mathematical framework to explore contact line motion through a disordered energy landscape.

  10. Constancy of spectral-line bisectors

    Gray, D.F.

    1983-01-01

    Bisectors of spectral line profiles in cool stars indicate the strength of convection in the photospheres of these objects. The present investigation is concerned with the feasibility of studying time variations in line bisectors, the reality of apparent line-to-line differences within the same stellar spectrum, and bisector differences between stars of identical spectral types. The differences considered pertain to the shape of the bisector. The material used in the investigation was acquired at the McDonald Observatory using a 1728 diode Reticon array at the coudefocus of the 2.1-m telescope. Observed bisector errors are discussed. It is established that different lines in the same star show significantly different bisectors. The observed error bands are shown by the shaded regions. The slope and curvature are unique for each case

  11. Infrared line intensities of chlorine monoxide

    Kostiuk, T.; Faris, J. L.; Mumma, M. J.; Deming, D.; Hillman, J. J.

    1986-01-01

    Absolute infrared line intensities of several ClO lines in the rotational-vibrational (1-0) band were measured using infrared heterodyne spectroscopy near 12 microns. A measurement technique using combined ultraviolet absorption and infrared line measurements near 9.5 microns and 12 microns permitted an accurate determination of the column densities of O3 and ClO in the absorption cell and thus improved ClO line intensities. Results indicate ClO line and band intensities approximately 2.4 times lower than previous experimental results. Effects of possible failure of local thermodynamic equilibrium conditions in the absorption cell and the implication of the results for stratospheric ClO measurements in the infrared are discussed.

  12. Correction of UBV Photometry for Emission Lines

    Skopal A.

    2003-12-01

    Full Text Available We investigate the effect on U,B,V magnitudes of the removal of emission lines from the spectra of some symbiotic stars and novae during their nebular phases. We approach this problem by the precise reconstruction of the composite UV/optical continuum and the line spectrum. The corrections ΔU, ΔB and ΔV are determined from the ratio of fluxes with and without emission lines. We demonstrate the effect for symbiotic nova V1016 Cyg during its nebular phase. We find that about 68%, 78% and 66% of the observed flux in the U, B and V filters is radiated in the emission lines. The effect should be taken into account before using the observed color indices of emission-line objects for diagnosis of their radiation in the continuum.

  13. A specialized bioengineering ion beam line

    Yu, L.D.; Sangyuenyongpipat, S.; Sriprom, C.; Thongleurm, C.; Suwanksum, R.; Tondee, N.; Prakrajang, K.; Vilaithong, T.; Brown, I.G.; Wiedemann, H.

    2007-01-01

    A specialized bioengineering ion beam line has recently been completed at Chiang Mai University to meet rapidly growing needs of research and application development in low-energy ion beam biotechnology. This beam line possesses special features: vertical main beam line, low-energy (30 keV) ion beams, double swerve of the beam, a fast pumped target chamber, and an in-situ atomic force microscope (AFM) system chamber. The whole beam line is situated in a bioclean environment, occupying two stories. The quality of the ion beam has been studied. It has proved that this beam line has significantly contributed to our research work on low-energy ion beam biotechnology

  14. The Pulse Line Ion Accelerator Concept

    Briggs, Richard J.

    2006-02-15

    The Pulse Line Ion Accelerator concept was motivated by the desire for an inexpensive way to accelerate intense short pulse heavy ion beams to regimes of interest for studies of High Energy Density Physics and Warm Dense Matter. A pulse power driver applied at one end of a helical pulse line creates a traveling wave pulse that accelerates and axially confines the heavy ion beam pulse. Acceleration scenarios with constant parameter helical lines are described which result in output energies of a single stage much larger than the several hundred kilovolt peak voltages on the line, with a goal of 3-5 MeV/meter acceleration gradients. The concept might be described crudely as an ''air core'' induction linac where the PFN is integrated into the beam line so the accelerating voltage pulse can move along with the ions to get voltage multiplication.

  15. Line radiative transfer and statistical equilibrium*

    Kamp Inga

    2015-01-01

    Full Text Available Atomic and molecular line emission from protoplanetary disks contains key information of their detailed physical and chemical structures. To unravel those structures, we need to understand line radiative transfer in dusty media and the statistical equilibrium, especially of molecules. I describe here the basic principles of statistical equilibrium and illustrate them through the two-level atom. In a second part, the fundamentals of line radiative transfer are introduced along with the various broadening mechanisms. I explain general solution methods with their drawbacks and also specific difficulties encountered in solving the line radiative transfer equation in disks (e.g. velocity gradients. I am closing with a few special cases of line emission from disks: Radiative pumping, masers and resonance scattering.

  16. Cavity lining after excavating caries lesions

    Schwendicke, Falk; Göstemeyer, Gerd; Gluud, Christian

    2015-01-01

    OBJECTIVES: After removal of dentin caries lesions, cavity lining has been advocated. Non-clinical data support this approach, but clinical data are sparse and ambiguous. We aimed at evaluating the benefits and harms of cavity lining using meta-analysis and Trial Sequential Analysis. DATA: We...... included randomized clinical trials comparing restorations without versus with cavity lining for treating primary caries lesions. Only trials reporting failure (defined as need to re-retreat) after ≥1 year follow-up were included. Trial selection, data extraction, and risk of bias assessment were conducted....... STUDY SELECTION: From 128 studies, three randomized trials (89/130 patients or teeth), all treating primary teeth, were included. The trials had high risk of bias. All trials compared no lining versus calcium hydroxide lining after selective caries removal followed by adhesive restoration. Follow...

  17. New Stokes' line in WKB theory

    Berk, H.L.; Nevins, W.M.; Roberts, K.V.

    1982-01-01

    The WKB theory for differential equations of arbitrary order or integral equations in one dimension is investigated. The rules previously stated for the construction of Stokes' lines for Nth-order differential equations, N> or =3, or integral equations are found to be incomplete because these rules lead to asymptotic forms of the solutions that depend on path. This paradox is resolved by the demonstration that new Stokes' lines can arise when previously defined Stokes' lines cross. A new formulation of the WKB problem is given to justify the new Stokes' lines. With the new Stokes' lines, the asymptotic forms can be shown to be independent of path. In addition, the WKB eigenvalue problem is formulated, and the global dispersion relation is shown to be a functional of loop integrals of the action

  18. Transmission Lines or Poles, Electric - VOLUSIA COUNTY MAJOR POWER LINES (Arcs)

    NSGIC Local Govt | GIS Inventory — Volusia County Power Line data was aggregated by using parcel data and visual inspection of 2005 aerial photography to determine centerline of Power Lines Right of...

  19. Cusps enable line attractors for neural computation

    Xiao, Zhuocheng; Zhang, Jiwei; Sornborger, Andrew T.; Tao, Louis

    2017-01-01

    Here, line attractors in neuronal networks have been suggested to be the basis of many brain functions, such as working memory, oculomotor control, head movement, locomotion, and sensory processing. In this paper, we make the connection between line attractors and pulse gating in feed-forward neuronal networks. In this context, because of their neutral stability along a one-dimensional manifold, line attractors are associated with a time-translational invariance that allows graded information to be propagated from one neuronal population to the next. To understand how pulse-gating manifests itself in a high-dimensional, nonlinear, feedforward integrate-and-fire network, we use a Fokker-Planck approach to analyze system dynamics. We make a connection between pulse-gated propagation in the Fokker-Planck and population-averaged mean-field (firing rate) models, and then identify an approximate line attractor in state space as the essential structure underlying graded information propagation. An analysis of the line attractor shows that it consists of three fixed points: a central saddle with an unstable manifold along the line and stable manifolds orthogonal to the line, which is surrounded on either side by stable fixed points. Along the manifold defined by the fixed points, slow dynamics give rise to a ghost. We show that this line attractor arises at a cusp catastrophe, where a fold bifurcation develops as a function of synaptic noise; and that the ghost dynamics near the fold of the cusp underly the robustness of the line attractor. Understanding the dynamical aspects of this cusp catastrophe allows us to show how line attractors can persist in biologically realistic neuronal networks and how the interplay of pulse gating, synaptic coupling, and neuronal stochasticity can be used to enable attracting one-dimensional manifolds and, thus, dynamically control the processing of graded information.

  20. Cusps enable line attractors for neural computation

    Xiao, Zhuocheng; Zhang, Jiwei; Sornborger, Andrew T.; Tao, Louis

    2017-11-01

    Line attractors in neuronal networks have been suggested to be the basis of many brain functions, such as working memory, oculomotor control, head movement, locomotion, and sensory processing. In this paper, we make the connection between line attractors and pulse gating in feed-forward neuronal networks. In this context, because of their neutral stability along a one-dimensional manifold, line attractors are associated with a time-translational invariance that allows graded information to be propagated from one neuronal population to the next. To understand how pulse-gating manifests itself in a high-dimensional, nonlinear, feedforward integrate-and-fire network, we use a Fokker-Planck approach to analyze system dynamics. We make a connection between pulse-gated propagation in the Fokker-Planck and population-averaged mean-field (firing rate) models, and then identify an approximate line attractor in state space as the essential structure underlying graded information propagation. An analysis of the line attractor shows that it consists of three fixed points: a central saddle with an unstable manifold along the line and stable manifolds orthogonal to the line, which is surrounded on either side by stable fixed points. Along the manifold defined by the fixed points, slow dynamics give rise to a ghost. We show that this line attractor arises at a cusp catastrophe, where a fold bifurcation develops as a function of synaptic noise; and that the ghost dynamics near the fold of the cusp underly the robustness of the line attractor. Understanding the dynamical aspects of this cusp catastrophe allows us to show how line attractors can persist in biologically realistic neuronal networks and how the interplay of pulse gating, synaptic coupling, and neuronal stochasticity can be used to enable attracting one-dimensional manifolds and, thus, dynamically control the processing of graded information.