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Sample records for linaire qui relie

  1. Un premier service mobile en Égypte qui relie les petits exploitants ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Un premier service mobile en Égypte qui relie les petits exploitants aux acheteurs. Un homme qui parle sur un téléphone mobile. Les petits exploitants agricoles dominent l'agriculture égyptienne, mais leur manque de connaissances en matière de commercialisation et de compétences techniques, ainsi qu'une mauvaise ...

  2. Relying on the Information

    Directory of Open Access Journals (Sweden)

    TK YAYIN KURULU

    2013-11-01

    Full Text Available The editorial discusses internet filtering in the light of the optional internet packages for users, namely Family, Standard, Kids and Domestic, to be offered by the Information Technologies Board with the "Secure Internet Law" to take effect on August 22, 2011. Also sharing the hesitations about the objectivity of the application with the reader, editorial emphasizes an education system focused on breeding citizens who are not scared of relying on the information and who can, by themselves, decide whether information is harmful or not. References are made to the results of similar applications abroad while the press statement made by Turkish NGOs on the issue are included.

  3. Archiver ce qui aurait pu avoir lieu

    Directory of Open Access Journals (Sweden)

    Stefanie Baumann

    2009-12-01

    Full Text Available L’Atlas Group, un projet de l’artiste libanais Walid Raad, est « dédié à la recherche et la compilation de documents sur l’histoire contemporaine libanaise. L’Atlas Group produit, localise, conserve et étudie des documents visuels, sonores, textuels et autres, qui mettent en lumière l’histoire actuelle du Liban. »Ce projet est ainsi présenté comme une fondation qui génère des archives historiques et qui collecte des traces relevant de la guerre au Liban afin de les mettre à disposition aux chercheurs. Mais, les matériaux sont produits par l’artiste : l’archive est imaginaire, les documents et récits sont inventés, ainsi que le Docteur Fakhouhi, le personnage principal, présenté comme étant « le plus renommé des historiens au Liban ». Le spectateur se trouve alors devant un scénario très étrange dans lequel sont détournées les notions de document (qui peut désormais être aussi bien trouvé que produit et d’histoire (car les situations décrites sont considérées comme « ayant très bien pu avoir eu lieu », l’Atlas Group  les traite comme de véritables événement historiques et qui déplace, mine de rien, tout un dispositif. Au sein de ce projet, la frontière entre fiction et documentaire est complètement estompée : le geste de l’artiste (qui, lui, se présente comme une institution, un « Groupe », interroge ainsi le statut même d’auteur vise à la déplacer pour poser des questions relatives aux représentations possibles de l’histoire, aux personnes aptes à se charger de son écriture et à l’opération historiographique.

  4. Nu, qui, où ?

    Directory of Open Access Journals (Sweden)

    Claire Hancock

    2004-04-01

    Full Text Available Si Francine Barthe-Deloizy semble s’excuser, dans la première phrase de son introduction, de commettre « un livre de plus sur la nudité, le nu, le corps », les géographes qui la liront ne partageront certainement pas cette lassitude : leur réaction devrait bien plutôt s’apparenter à « enfin, une géographie du nu et du corps !». Peut-être par pudibonderie, ou peut-être parce que le géographe français aime à se penser comme pur esprit, notre discipline a longtemps ...

  5. 11 batailles qui ont fait la Bretagne

    OpenAIRE

    Pansini, Valeria

    2017-01-01

    L’ouvrage collectif dirigé par Dominique Le Page couvre, à travers les faits de guerre qui ont touché la région, deux millénaires d’histoire de la Bretagne, de l’affrontement entre la flotte romaine et les Vénètes du Morbihan en 56 av. J.-C. à la bataille du maquis de Saint Marcel en juin 1944. L’attention portée par les onze contributions à la mémoire de l’événement analysé rend ce très impressionnant laps de temps étudié encore plus long, en emmenant l’attention du lecteur jusqu’à nos jours...

  6. Qui gouverne les industries ?

    Directory of Open Access Journals (Sweden)

    William Genieys

    2010-07-01

    Full Text Available La question de savoir qui gouverne l’économie a longtemps fasciné les sciences sociales sans pour autant souvent générer de résultats probants et rigoureux. Bernard Jouve a tenté d’y répondre en se focalisant sur l’élite de chacune des métropoles qu’il a étudiée. Ce texte prolonge son travail en changeant de focale pour aborder plutôt les élites qui régulent chaque industrie en présentant leur «  programme » respectif. Après avoir exposé les développements théoriques menant à ce concept « d’élite programmatique », l’article les croise avec une approche du gouvernement des industries afin de tracer une nouvelle voie vers une meilleure compréhension du rôle du politique dans l’économie.The question «who governs the economy ?» has fascinated social science for years without often generating stimulating and rigorous results. Bernard Jouve attempted to reply to it by focusing on the elite of each metropole he studied. This text extends his work by changing the focus in order to study the elites who regulate each industry through promoting their respective «programme». Having first presented the theoretical developments that produced the concept of «programmatic elite», the article combines it with an approach to the government of industries in order to set out a new route map towards better understanding of the role of politics in the economy.

  7. Maladies reliées aux loisirs aquatiques

    Science.gov (United States)

    Sanborn, Margaret; Takaro, Tim

    2013-01-01

    Résumé Objectif Passer en revue les facteurs de risque, la prise en charge et la prévention des maladies reliées aux loisirs aquatiques en pratique familiale. Sources des données Des articles originaux et de synthèse entre janvier 1998 et février 2012 ont été identifiés à l’aide de PubMed et des expressions de recherche en anglais water-related illness, recreational water illness et swimmer illness. Message principal Il y a un risque de 3 % à 8 % de maladies gastrointestinales (MGI) après la baignade. Les groupes à risque élevé de MGI sont les enfants de moins de 5 ans, surtout s’ils n’ont pas été vaccinés contre le rotavirus, les personnes âgées et les patients immunodéficients. Les enfants sont à plus grand risque parce qu’ils avalent plus d’eau quand ils nagent, restent dans l’eau plus longtemps et jouent dans l’eau peu profonde et le sable qui sont plus contaminés. Les adeptes des sports dans lesquels le contact avec l’eau est abondant comme le triathlon et le surf cerf-volant sont aussi à risque élevé et même ceux qui s’adonnent à des activités impliquant un contact partiel avec l’eau comme la navigation de plaisance et la pêche ont un risque de 40 % à 50 % fois plus grand de MGI par rapport à ceux qui ne pratiquent pas de sports aquatiques. Il y a lieu de faire une culture des selles quand on soupçonne une maladie reliée aux loisirs aquatiques et l’échelle clinique de la déshydratation est utile pour l’évaluation des besoins de traitement chez les enfants affectés. Conclusion Les maladies reliées aux loisirs aquatiques est la principale cause de MGI durant la saison des baignades. La reconnaissance que la baignade est une source importante de maladies peut aider à prévenir les cas récurrents et secondaires. On recommande fortement le vaccin contre le rotavirus chez les enfants qui se baignent souvent.

  8. Deux nouvelles initiatives visent à soutenir les femmes qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    14 nov. 2017 ... Chilufya MWEWA PhD Student University of Cape Town Dept of Physics Cape Town South Africa. Dans les pays en développement, les femmes se heurtent encore à des obstacles qui limitent leur capacité à faire une carrière et à devenir des chefs de file dans le domaine des sciences, de la technologie, ...

  9. Juxtaposed Color Halftoning Relying on Discrete Lines

    OpenAIRE

    Babaei, Vahid; Hersch, Roger

    2013-01-01

    Most halftoning techniques allow screen dots to overlap. They rely on the assumption that the inks are transparent, i.e. the inks do not scatter a significant portion of the light back to the air. However, many special effect inks such as metallic inks, iridescent inks or pigmented inks are not transparent. In order to create halftone images, halftone dots formed by such inks should be juxtaposed, i.e. printed side by side. We propose an efficient juxtaposed color halftoning technique for pla...

  10. An atom trap relying on optical pumping

    International Nuclear Information System (INIS)

    Bouyer, P.; Lemonde, P.; Ben Dahan, M.; Michaud, A.; Salomon, C.; Dalibard, J.

    1994-01-01

    We have investigated a new radiation pressure trap which relies on optical pumping and does not require any magnetic field. It employs six circularly polarized divergent beams and works on the red of a J g →J e = J g + 1 atomic transition with J g ≥1/2. We have demonstrated this trap with cesium atoms from a vapour cell using the 852 nm J g = 4→J e = 5 resonance transition. The trap contained up to 3.10 7 atoms in a cloud of 1/√e radius of 330 μm. (orig.)

  11. Juxtaposed color halftoning relying on discrete lines.

    Science.gov (United States)

    Babaei, Vahid; Hersch, Roger D

    2013-02-01

    Most halftoning techniques allow screen dots to overlap. They rely on the assumption that the inks are transparent, i.e., the inks do not scatter a significant portion of the light back to the air. However, many special effect inks, such as metallic inks, iridescent inks, or pigmented inks, are not transparent. In order to create halftone images, halftone dots formed by such inks should be juxtaposed, i.e., printed side by side. We propose an efficient juxtaposed color halftoning technique for placing any desired number of colorant layers side by side without overlapping. The method uses a monochrome library of screen elements made of discrete lines with rational thicknesses. Discrete line juxtaposed color halftoning is performed efficiently by multiple accesses to the screen element library.

  12. Regarder ceux qui regardent : Eudora Welty photographe

    Directory of Open Access Journals (Sweden)

    Jean-Marc Victor

    2010-02-01

    Full Text Available Biographes et critiques ont largement souligné la concomitance, chez Eudora Welty, de la venue à l’écriture et de la pratique photographique au milieu des années 30 : en 1936, elle obtient en même temps, et pour la première fois, la publication d’une de ses nouvelles (« Death of Traveling Salesman » ainsi que la tenue d’une exposition, dans une galerie new-yorkaise, de ses photographies du Mississippi prises pour le compte de l’agence locale de la Works Progress Administration, qui l’emploie...

  13. Qui a droit à la pensée ?

    Directory of Open Access Journals (Sweden)

    Patricia Desroches

    2010-06-01

    Full Text Available Les Éditions Amsterdam ont publié en septembre 2009 un ouvrage intitulé Et tant pis pour les gens fatigués , constitué d’une série d’entretiens réalisés avec le philosophe Jacques Rancière, sur une période allant de 1976 à 2009. L’intérêt de cette publication est de rendre présente l’œuvre d’un philosophe qui a scruté « les figures concrètes d’ouvriers » (p. 37, sans revendiquer une position d’historien ; d’un théoricien sensible à la dimension ...

  14. L'univers quantique tout ce qui peut arriver arrive

    CERN Document Server

    Cox, Brian

    2018-01-01

    Brian Cox et Jeff Forshaw révèlent dans cet ouvrage la signification profonde de la physique quantique. Ils montrent pourquoi elle fournit une description de la Nature avec un immense pouvoir prédictif et explicatif, couvrant une vaste gamme de phénomènes, des puces de silicium aux fonctionnement des étoiles. L'histoire commence au tournant du XXe siècle, avec l'hypothèse de Max Planck qui postule que le rayonnement lumineux dégagé par un corps chaud est constituée de petits paquets d'énergie qu'il nomme "quanta". Brian Cox et Jeff Forshaw explorent ensuite plus d'un siècle de découvertes et de questionnements, jusqu'au fameux boson de higgs, clé de voûte du modèle standard décrivant la matière à son niveau le plus élémentaire.

  15. 'Des Yeux Qui Ne Voient Pas...': The smartphones

    Directory of Open Access Journals (Sweden)

    Luca Di Lorenzo

    2018-04-01

    Full Text Available Three of the most influential chapters of Le Corbusier’s Vers une Architecture are collected under the common title ‘Des yeux qui ne voient pas…’ (Eyes which do not see…. Liners, airplanes, and automobiles are shown as the expression of the powerful beauty of practical form: honest, simple, functional and technological. These very famous pages remind us that form is not only derived from precise typological choices or from reasoned morphogenetic diagrams, but it could also be a direct expression of the Kunstwollen. What are the paquebots of the twenty-first century? Which buildings embody this new paradigm? This graphic analysis starts from the statement that one of the ‘not seen’ features of this era is the smartphone. The subject of the survey is the first BMW Guggenheim Lab, designed in 2010 by Atelier Bow-Wow. Described by the architects themselves as a ‘travel toolbox’ or ‘pop-up fly loft theatre in the city’, this compact architecture is the incarnation of three interesting formal qualities usually associated with smartphones: the clear division between the hardware and the ergonomic user interface; the possibility to operate different functions (or software in the same space (or screen; and the real and virtual connection with different urban situations.

  16. La vérite sur ce qui nous motive

    CERN Document Server

    Pink, Daniel H

    2011-01-01

    Voici enfin la traduction française du best-seller international DRIVE ! Qu'est-ce qui nous motive vraiment ? Dans quels cas sommes-nous les plus performants et les plus enthousiastes ? La plupart d'entre nous sommes persuadés que les récompenses (salaire, primes...) sont notre meilleure motivation. La logique de la carotte et du bâton finalement... Et si nous faisions fausse route ? En s'appuyant sur quatre décennies d'études scientifiques et psychologiques sur la motivation humaine, Pink démontre que les entreprises dirigent très mal leurs équipes avec d'énormes conséquences sur notre vie (absence d'ambition, lassitude, morosité). Le secret de la performance (et de la satisfaction) dans les entreprises, l'enseignement ou dans notre vie personnelle , c'est le besoin profondément humain de diriger sa propre vie, d'apprendre, de créer de nouvelles choses et de s'améliorer. Dans ce livre, Pink examine les 3 éléments de la motivation, l'autonomie, la maîtrise et le besoin de donner un sens ...

  17. Alternative Fuels Data Center: Colorado Airport Relies on Natural Gas

    Science.gov (United States)

    Fueling Stations Colorado Airport Relies on Natural Gas Fueling Stations to someone by E-mail Share Alternative Fuels Data Center: Colorado Airport Relies on Natural Gas Fueling Stations on Facebook Tweet about Alternative Fuels Data Center: Colorado Airport Relies on Natural Gas Fueling Stations on

  18. Interdiction de Genre: La Loi Qui Fait Taire le Corp

    Directory of Open Access Journals (Sweden)

    Renato Duro Dias

    2015-12-01

    Full Text Available Cette recherche discute les identités de genre avec la base dans l'analyse du travail La Ley no escrita (2012 d'Oihana Cordero. Le travail de l'artiste plasticien a comme l'objectif provoque la réflexion sur les lois et les normes juridiques-sociales qu'ils existent autour du caractère ficcional et le genre performatife, révélant de nouvelles lectures sur l'acte du corps. C'est un travail sculptural (KRAUSS, 1984, composé par une base blanche, une épée et un groupe de feuilles, dans lesquelles ils sont exprimés, par un contrat de genre, comme ils se prononcent, interseccionam et c'est des interdictions imposées aux possibilités de genre. Comme ceci, les règles et des règlements sont faits la preuve imposés par le binarisme du genre que la force soumet et ils arrêtent des identités pour le compte de la normalisation (normatisation des corps. Pour cette enquête les concepts de genre sont problematize, le corps subjugué, la normativité et de la performance dans le Butler (2012a, 2012b, 2013, Foucault (1997, 1998, 2014, Fraser (2002, 2006, 2009, Scott (2008, Cordero (2012 et Preciado (2011. Cordero (2012, dans son travail, nous présente les copies multiples d'un contrat de papier imprimé a passé par une épée. C'est une métaphore, une forme de représentation dogmatizé du corps par les actes visibles et invisibles qui compose et ils naturalisent les identités de genre dans une dualité obscurantiste homme/femme. Ce travail comme l'objet conceptuel (FREIRE 2006 produit la puissance exprimée pour en plus d'un document légal perforé, elle vise à provoquer les gens de contempler sur leurs pratiques et leurs corps, mais, par-dessus tout, réfléchir comme ces périmètres ont de transgression difficile. Lors de l'analyse de l'intersection possible des identités de genre et un objet artistique dans le domaine juridique est prévu pour gérer des éléments capables de révéler les technologies complexes corporels politiques

  19. Generic UAV Modeling to Obtain Its Aerodynamic and Control Derivatives

    National Research Council Canada - National Science Library

    Chua, Choon S

    2008-01-01

    .... The first approach explored in this thesis involves using the LinAir software program developed about a decade ago at Stanford University, the second one relies on the Athena Vortex Lattice package...

  20. Une étude examine les liens qui existent entre la protection sociale ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Gasparini et Cruces et Carolina Robino, administratrice de programme au CRDI, qui a été publié dans El Economista. Cette étude s'inscrit dans le projet Marchés du travail et croissance partagée en Amérique latine, qui est financé par le CRDI et coordonné par le CEDLAS. Le projet vise à faire la lumière sur les rouages ...

  1. Biodiversité et santé : Tuons-nous les plantes qui peuvent nous ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 févr. 2011 ... Si cette tendance est récente, la plupart de ces produits de « médecines ... des maladies les plus graves qui affligent le monde, peut-être même face au sida. ... trop quel conseil je pourrais donner aux chercheurs qui tenteront, en 2050, de créer de ... Les populations les plus démunies sont à l'origine de la ...

  2. Reliģijas makdonaldizācija

    OpenAIRE

    Siliņš, Toms

    2012-01-01

    Bakalaura darbā apskatītas makdonaldizācijas procesa izpausmes Latvijas reliģisko organizāciju darbībā. Pētījuma mērķis ir noskaidrot makdonaldizācijas izpausmes Latvijas reliģiskajās organizācijās, tādēļ izvirzīti pētījuma jautājumi – kādas ir liecības par makdonaldizācijas procesa ietekmi uz reliģiskajām organizācijām Latvijā un kā vērtējama makdonaldizācijas procesa ietekme uz reliģiskajām organizācijām Latvijā. Pētījuma ietvaros veiktas divas ekspertu intervijas, kuru analīzes rezultātā i...

  3. In search of Godard’s ‘Sauve la vie (qui peut’

    Directory of Open Access Journals (Sweden)

    Michael Witt

    2015-04-01

    Full Text Available This article examines a little-known compilation film titled Sauve la vie (qui peut that Jean-Luc Godard created in 1981 within the framework of a series of lectures on cinema history that he delivered in Rotterdam in 1980-1981. To make this compilation film he combined sections from his Sauve qui peut (la vie with extracts from four other films. Based on archival research, the article considers the context for the screening, the film’s structure, Godard’s wider engagement with the filmmakers whose work he incorporated, the prints he used, my attempts to reconstruct the film, and its reception in 1981 and today.

  4. 77 FR 27245 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN

    Science.gov (United States)

    2012-05-09

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N069; FXRS1265030000S3-123-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN AGENCY: Fish and... plan (CCP) and environmental assessment (EA) for Big Stone National Wildlife Refuge (Refuge, NWR) for...

  5. Rapport financier trimestriel pour le trimestre qui a pris fin le 30 juin ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    30 juin 2017 ... Régi par la Loi sur le Centre de recherches pour le développement international ... des retombées; forme des leaders dans les secteurs de l'administration .... Au cours de la période de trois mois qui a pris fin le 30 juin 2017, ...

  6. Kenya : De la viande qui fait « bizz »Primary tabs | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    23 sept. 2016 ... Il effectue présentement son travail de terrain chez Sanergy, une entreprise de Nairobi qui offre un service de toilettes publiques dans les bidonvilles, pour ensuite transformer leur contenu en ... Le Centre se spécialise dans la gestion des insectes nuisibles depuis sa fondation, dans les années 1970.

  7. «¿Quién soy yo? ¿Quiénes son ellos/as?». Personajes en busca de identidad

    Directory of Open Access Journals (Sweden)

    Caretti, Laura

    2006-12-01

    Full Text Available Who am I? Who are they? These are the questions haunting the characters, created by writers such as Ibsen, Pirandello, Beckett and others, whose emblematic search for identity is explored in the article. The complex interconnections between subjectivity and alterity are focused within the coordinates of space (society and time (memory in their outward and inward movement. The characters are seen on stage relating also to the otherness of actors and spectators. Particular relief is given to the difference between the female and male search for identity in the light of contemporary historical changes.¿Quién soy yo? ¿Quiénes son ellos/as? Estas son las cuestiones que obsesionan a los personajes creados por escritores como Ibsen, Pirandello, Beckett y otros, cuya emblemática búsqueda de identidad se explora a lo largo de este artículo. Las complejas interconexiones entre subjetividad y alteridad son analizadas con las coordenadas del espacio (sociedad y el tiempo (memoria en su movimiento interno y externo. Los personajes son vistos en el escenario desde la alteridad de actores y espectadores. Un particular relieve se otorga a la diferencia entre la búsqueda de la identidad femenina y masculina a la luz de los cambios históricos contemporáneos.

  8. Intuitive Face Judgments Rely on Holistic Eye Movement Pattern

    Directory of Open Access Journals (Sweden)

    Laura F. Mega

    2017-06-01

    Full Text Available Non-verbal signals such as facial expressions are of paramount importance for social encounters. Their perception predominantly occurs without conscious awareness and is effortlessly integrated into social interactions. In other words, face perception is intuitive. Contrary to classical intuition tasks, this work investigates intuitive processes in the realm of every-day type social judgments. Two differently instructed groups of participants judged the authenticity of emotional facial expressions, while their eye movements were recorded: an ‘intuitive group,’ instructed to rely on their “gut feeling” for the authenticity judgments, and a ‘deliberative group,’ instructed to make their judgments after careful analysis of the face. Pixel-wise statistical maps of the resulting eye movements revealed a differential viewing pattern, wherein the intuitive judgments relied on fewer, longer and more centrally located fixations. These markers have been associated with a global/holistic viewing strategy. The holistic pattern of intuitive face judgments is in line with evidence showing that intuition is related to processing the “gestalt” of an object, rather than focusing on details. Our work thereby provides further evidence that intuitive processes are characterized by holistic perception, in an understudied and real world domain of intuition research.

  9. Intuitive Face Judgments Rely on Holistic Eye Movement Pattern.

    Science.gov (United States)

    Mega, Laura F; Volz, Kirsten G

    2017-01-01

    Non-verbal signals such as facial expressions are of paramount importance for social encounters. Their perception predominantly occurs without conscious awareness and is effortlessly integrated into social interactions. In other words, face perception is intuitive. Contrary to classical intuition tasks, this work investigates intuitive processes in the realm of every-day type social judgments. Two differently instructed groups of participants judged the authenticity of emotional facial expressions, while their eye movements were recorded: an 'intuitive group,' instructed to rely on their "gut feeling" for the authenticity judgments, and a 'deliberative group,' instructed to make their judgments after careful analysis of the face. Pixel-wise statistical maps of the resulting eye movements revealed a differential viewing pattern, wherein the intuitive judgments relied on fewer, longer and more centrally located fixations. These markers have been associated with a global/holistic viewing strategy. The holistic pattern of intuitive face judgments is in line with evidence showing that intuition is related to processing the "gestalt" of an object, rather than focusing on details. Our work thereby provides further evidence that intuitive processes are characterized by holistic perception, in an understudied and real world domain of intuition research.

  10. Robust Sensing of Approaching Vehicles Relying on Acoustic Cues

    Directory of Open Access Journals (Sweden)

    Mitsunori Mizumachi

    2014-05-01

    Full Text Available The latest developments in automobile design have allowed them to be equipped with various sensing devices. Multiple sensors such as cameras and radar systems can be simultaneously used for active safety systems in order to overcome blind spots of individual sensors. This paper proposes a novel sensing technique for catching up and tracking an approaching vehicle relying on an acoustic cue. First, it is necessary to extract a robust spatial feature from noisy acoustical observations. In this paper, the spatio-temporal gradient method is employed for the feature extraction. Then, the spatial feature is filtered out through sequential state estimation. A particle filter is employed to cope with a highly non-linear problem. Feasibility of the proposed method has been confirmed with real acoustical observations, which are obtained by microphones outside a cruising vehicle.

  11. Une percée qui permet de fournir toute une industrie en petits ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    28 oct. 2010 ... Au cours des années 1970 et 1980, le CRDI a consenti un soutien technique et financier appréciable à ces travaux. ... En outre, le centre a enseigné à des pêcheurs qui récoltent des alevins sauvages de meilleures méthodes de manipulation et de transport de ces petits organismes de 1,5 cm de longueur, ...

  12. Rapport financier trimestriel pour le trimestre qui a pris fin le 31

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    31 déc. 2011 ... politiques, de chercheurs et de collectivités de par le monde. ..... qui a été choisi à l'issue d'un processus de recrutement mené ... Les bureaux régionaux constituent une ressource stratégique et un élément clé du modèle de.

  13. Des bananes plus nutritives et qui résistent aux maladies | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    28 oct. 2010 ... Les petits agriculteurs jouissent de meilleurs revenus et d'une sécurité alimentaire accrue grâce à des variétés de bananes à haut rendement qui résistent aux maladies. Au cours des années 1980 et 1990, avec le soutien du CRDI, la Fundación Hondureña de Investigación Agricola (FHIA) a mis au point ...

  14. Tache mongoloïde extensive : Un signe clinique qui mérite une ...

    African Journals Online (AJOL)

    Tache mongoloïde extensive : Un signe clinique qui mérite une attention particulière. R Abilkassem, A Agadr. Abstract. No abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.11604/pamj.2013.16.41.3062 · AJOL African Journals ...

  15. Ceux qui sauront : le déclinisme uchronique de Pierre Bordage

    Directory of Open Access Journals (Sweden)

    Tayeb Ainseba

    2015-01-01

    Full Text Available “What if the French Revolution had never happened? What if what seems to be France's greatest pride was simply erased from history books? These are the questions that haunt Pierre Bordage's alternate history fiction Ceux qui sauront (Those who know which was published in 2008 and is the first volume of a trilogy (Ceux qui rêvent (Those who dream, 2010; Ceux qui osent (Those who dare, 2012. Bordage does not outline all the political ramifications of this null and void revolution but his narrative is centred on the prohibition of teaching for the enduring Third Estate. Even though it has been labelled children's literature, this work of alternate history is full of violent declinism: it tackles both the State's misology and the way scholars are disdained within a mercantile order, it denounces the way politics have abandoned the social and the way school has been forced to secrecy. Given these declinist characteristics, might we not classify this alternate history as a distopia? What are the whys and the wherefores of this all-French anti-humanism? What does this work reveal as regards contemporary, end of twentieth, beginning of twenty-first century France?

  16. Ceux qui sauront : le déclinisme uchronique de Pierre Bordage

    Directory of Open Access Journals (Sweden)

    Tayeb Ainseba

    2015-12-01

    Full Text Available “What if the French Revolution had never happened? What if what seems to be France's greatest pride was simply erased from history books? These are the questions that haunt Pierre Bordage's alternate history fiction Ceux qui sauront (Those who know which was published in 2008 and is the first volume of a trilogy (Ceux qui rêvent (Those who dream, 2010; Ceux qui osent (Those who dare, 2012. Bordage does not outline all the political ramifications of this null and void revolution but his narrative is centred on the prohibition of teaching for the enduring Third Estate. Even though it has been labelled children's literature, this work of alternate history is full of violent declinism: it tackles both the State's misology and the way scholars are disdained within a mercantile order, it denounces the way politics have abandoned the social and the way school has been forced to secrecy. Given these declinist characteristics, might we not classify this alternate history as a distopia? What are the whys and the wherefores of this all-French anti-humanism? What does this work reveal as regards contemporary, end of twentieth, beginning of twenty-first century France?

  17. da Vinci decoded: does da Vinci stereopsis rely on disparity?

    Science.gov (United States)

    Tsirlin, Inna; Wilcox, Laurie M; Allison, Robert S

    2012-11-01

    In conventional stereopsis, the depth between two objects is computed based on the retinal disparity in the position of matching points in the two eyes. When an object is occluded by another object in the scene, so that it is visible only in one eye, its retinal disparity cannot be computed. Nakayama and Shimojo (1990) found that a precept of quantitative depth between the two objects could still be established for such stimuli and proposed that this precept is based on the constraints imposed by occlusion geometry. They named this and other occlusion-based depth phenomena "da Vinci stereopsis." Subsequent research found quantitative depth based on occlusion geometry in several other classes of stimuli grouped under the term da Vinci stereopsis. However, Nakayama and Shimojo's findings were later brought into question by Gillam, Cook, and Blackburn (2003), who suggested that quantitative depth in their stimuli was perceived based on conventional disparity. In order to understand whether da Vinci stereopsis relies on one type of mechanism or whether its function is stimulus dependent we examine the nature and source of depth in the class of stimuli used by Nakayama and Shimojo (1990). We use three different psychophysical and computational methods to show that the most likely source for depth in these stimuli is occlusion geometry. Based on these experiments and previous data we discuss the potential mechanisms responsible for processing depth from monocular features in da Vinci stereopsis.

  18. Human children rely more on social information than chimpanzees do.

    Science.gov (United States)

    van Leeuwen, Edwin J C; Call, Josep; Haun, Daniel B M

    2014-11-01

    Human societies are characterized by more cultural diversity than chimpanzee communities. However, it is currently unclear what mechanism might be driving this difference. Because reliance on social information is a pivotal characteristic of culture, we investigated individual and social information reliance in children and chimpanzees. We repeatedly presented subjects with a reward-retrieval task on which they had collected conflicting individual and social information of equal accuracy in counterbalanced order. While both species relied mostly on their individual information, children but not chimpanzees searched for the reward at the socially demonstrated location more than at a random location. Moreover, only children used social information adaptively when individual knowledge on the location of the reward had not yet been obtained. Social information usage determines information transmission and in conjunction with mechanisms that create cultural variants, such as innovation, it facilitates diversity. Our results may help explain why humans are more culturally diversified than chimpanzees. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  19. [Scope of the latest RE-LY substudies: clinical implications].

    Science.gov (United States)

    Ruiz-Giménez Arrieta, N

    2012-03-01

    The approval of the use of dabiatran in stroke prevention in patients with nonvalvular atrial fibrilation (NVAF) is based on the results of the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial, one of the largest studies to date in this entity. In this trial, dabigatran showed similar safety and efficacy to warfarin in primary and secondary prevention of stroke in patients with AF. At a dose of 150 mg twice daily, dabigatran was superior to warfarin in the prevention of stroke or systemic embolism and the 110 mg dose twice daily showed similar efficacy and greater safety, given the lower incidence of hemorrhage. These results were consistently found in the various subanalyses, with some slight differences of interest for clinical practice. The ideal candidates for dabiatran are patients with NVAF suitable for cardioversion, who require short periods of anticoagulation, patients in remote geographical areas with difficulty in achieving good anticoagulation control or good control with anti-vitamin K treatment due to IRN fluctuations, and patients with a low risk of hemorrhage and a CHADS score ≥ 3 and/or with prior stroke, whenever there are no contraindications. The choice of dabigatran dose should be evaluated according to the patient's individual characteristics (caution must be exercised when prescribing this drug in the elderly and in renal insufficiency) and embolic and/or hemorrhagic risk. Studies of the long-term safety of this drug, pharmacoeconomic analyses in Spain and post-commercialization pharmacovigilance data are required before the definitive uses of this drug can be established. Copyright © 2012 Elsevier España, S.L. All rights reserved.

  20. pour le trimestre qui a pris fin le 30 septembre 2014

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    30 sept. 2014 ... d'information financière (normes IFRS). Toutes les ... 42,9 %. (1 684) d'un exercice à l'autre. Écart en %. Budget. 2014-2015. Période de six mois qui a pris fin le 30 septembre. Réalisations. Réalisations. 2013 ... a augmenté de 9,6 millions de dollars (soit 17,5 %) par rapport à ce qu'elle était à la période.

  1. OPS : élaborer de nouveaux partenariats et consolider ceux qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    9 mai 2011 ... L'Organisation mondiale de la santé (OMS) « est devenue très engagée [en ce qui a trait à l'écosanté] quand l'Évaluation des écosystèmes pour le millénaire a été faite, » a indiqué le Dr Corvalan. Entreprise en 2001, l'Évaluation des écosystèmes pour le millénaire a evalué les conséquences du ...

  2. Qui a peur du harcèlement sexuel ? des femmes témoignent

    CERN Document Server

    Ducret, Véronique

    2010-01-01

    Le harcèlement sexuel au travail est un comportement banalisé tant par les auteurs que par les collègues et les responsables hiérarchiques. Cette attitude contribue à maintenir les victimes dans le silence et c'est pour briser ce cercle que Véronique Ducret a choisi de récolter et publier les témoignages de dix femmes. Les parcours de ces femmes, semés d'embûches, montrent qu'elles ont essayé de se faire entendre ; pour certaines, au risque de perdre leur place de travail. Si le harcèlement sexuel est douloureux, plus insupportable encore est l'incompréhension à laquelle elles ont dû faire face. Ces femmes témoignent ici des stratégies qu'elles ont utilisées pour faire reconnaître ce qu'elles ont subi. Cet ouvrage s'adresse à toutes les femmes qui travaillent et qui ont été ou risquent d'être confrontées un jour au harcèlement sexuel. Ces récits permettront à certaines de se reconnaître dans ces situations et peut-être de dévoiler à leur tour, et sans honte, les violences sexuel...

  3. Choix qui s'offrent à la Chine en matière de politiques à la suite de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ce projet, qui est le prolongement d'un projet antérieur - Réseau de recherche sur la pauvreté et les inégalités en Chine (no 103310) - est amorcé en raison du débat qui a actuellement cours en Chine sur la crise économique mondiale. Cette subvention permettra à de jeunes chercheurs de contribuer au débat en ...

  4. De l’ethnologie du Japon : par qui, où, comment ?

    Directory of Open Access Journals (Sweden)

    Anne Bouchy

    2007-06-01

    Full Text Available « Ce qui importe, c’est que l’esprit humain, sans égard pour l’identité de ses messagers occasionnels, y [dans ce livre] manifeste une structure de mieux en mieux intelligible à mesure que progresse la démarche doublement réflexive de deux pensées agissant l’une sur l’autre et dont, ici l’une, là l’autre, peut être la mèche ou l’étincelle du rapprochement desquelles jaillira leur commune illumination. Et, si celle-ci vient à révéler un trésor, on n’aura pas besoin d’arbitre pour procéder au p...

  5. La crisis bancaria de 1999 en el Ecuador: un análisis a partir del Cuadro de Operaciones Financieras (COF) y la matriz de flujo de fondos de "quién a quién"

    OpenAIRE

    Salguero Llanos, Magally

    2005-01-01

    Este trabajo toma como referencia al Cuadro de Operaciones Financiera (COF) y la Matriz de Flujo de Fondos de "quién a quién " de las Cuentas Nacionales del Ecuador, interrelacionando sus resultados con las condiciones macro económicas y microeconómicas bajo las cuales se desarrolló la crisis bancaria de 1999. A nivel microeconómico, se observan las pruebas estadísticas y variables con las respuestas de los bancos frente a la crisis. Se analiza la interacción entre sectores y transacciones fi...

  6. Alternative Fuels Data Center: St. Louis Airport Relies on Biodiesel and

    Science.gov (United States)

    Natural Gas Vehicles St. Louis Airport Relies on Biodiesel and Natural Gas Vehicles to someone by E-mail Share Alternative Fuels Data Center: St. Louis Airport Relies on Biodiesel and Natural Gas Vehicles on Facebook Tweet about Alternative Fuels Data Center: St. Louis Airport Relies on Biodiesel and

  7. Le soja local en Allemagne, une demande soutenue, une offre qui s’étoffe

    Directory of Open Access Journals (Sweden)

    Recknagel Jürgen

    2015-09-01

    Full Text Available Depuis 2009, la sole de soja ne cesse d’augmenter en Allemagne, surtout dans le sud du pays mais aussi à l’est et un peu partout dans les régions au climat propice. Un programme national a permis de créer les références nécessaires pour un conseil qualifié apporté aux agriculteurs via un réseau de développement. Ainsi toute une filière soja est déjà bien avancée dans le sud et en cours de mise en place dans le reste du pays, pour organiser la collecte auprès des producteurs et obtenir une offre groupée pour les transformateurs pour l’alimentation animale et humaine. Le soja allemand ne veut pas rivaliser avec le soja OGM ni pour instant avec le soja non-OGM des Amériques mais vise plutôt les filières courtes régionales et le marché bio qui est encore plus déficitaire en auto-approvisionnement que le conventionnel. Avec 10 000 ha en 2014, dont 25 % en bio, le soja en Allemagne est encore loin de la surface du maïs grain (2008–2014 autour de 500 000 ha. En pratique, 20 % de ces surfaces de maïs au climat a priori propice pourraient représenter le potentiel réel pour le soja en Allemagne, sous condition de prix garantissant une rentabilité suffisante par rapport aux autres grandes cultures. Pour les programmes non-OGM des grands distributeurs, il faut de toute façon une base de production élargie comme celle proposée par l’initiative Danube-Soja, qui dans une version Europe-Soja engloberait aussi la France. Avec le verdissement de la PAC et la montée du cours du Dollar par rapport à l’Euro, les perspectives pour une augmentation de la surface de production de soja en Allemagne et en Europe paraissent bonnes. Maintenant il faut travailler sur les débouchés pour garantir l’absorption de la production grandissante par les marchés et les consommateurs à tous les niveaux : régional, national et européen.

  8. What Will the New Generation Generate? Gendering Accumulation in Fatou Diome’s Celles qui attendent

    Directory of Open Access Journals (Sweden)

    Christopher Hogarth

    2014-01-01

    Full Text Available In this paper I focus on the penultimate installment of the oeuvre of the much-celebrated Franco-Senegalese writer Fatou Diome, whose largely autobiographical work has garnered a wide following and a lucrative contract with the Flammarion publishing house. I propose that Diome’s 2010 novel Celles qui attendent strongly contributes to a discourse surrounding the roles of males and females in an African economy increasingly dominated by migration. Diome started as a writer who portrayed the empowered role of the female migrant, who is able to accumulate financial capital in Europe and send it back to Africa in order for males to slowly hoard goods and start businesses. Her more recent work, however, has been marked by a shift to reflect a portrait of Senegalese society and migration that is backed by sociological studies: men take on the role of migrants, tempted by “marchands d’illusions” 'merchants of illusions,' but are also determined to get away from social pressures in order to accumulate their own set of experiences in the world, at a distance from the expectations of a traditional African society. Women, on the other hand, are left in extreme proximity to the problems of everyday life on a cash-starved continent, as they have to go about the business of surviving and raising children, engaging in many forms of hoarding that have to do with accumulating finance, memories and myths.

  9. 78 FR 3911 - Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive...

    Science.gov (United States)

    2013-01-17

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R3-R-2012-N259; FXRS1265030000-134-FF03R06000] Big Stone National Wildlife Refuge, Big Stone and Lac Qui Parle Counties, MN; Final Comprehensive... significant impact (FONSI) for the environmental assessment (EA) for Big Stone National Wildlife Refuge...

  10. Guide en matière d'évaluation à l'intention des instances qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les évaluations sont un élément clé de la recherche pour le développement, puisqu'elles ... Comprendre le rôle des instances qui commandent des évaluations ... Avec l'aide du CRDI, l'Instituto de la Salud, Medio Ambiente, Economia y ...

  11. Communication des risques reliés aux changements climatiques en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 janv. 2012 ... Il incombe bien sûr aux gouvernements locaux et nationaux de prendre les décisions relatives à l'adaptation aux changements climatiques; ils doivent toutefois les communiquer aux ménages, aux groupes communautaires et aux entreprises privées afin que ceux-ci prennent les décisions qui s'imposent ...

  12. Académico Correspondiente Arturo Morillo Quiñones (1925-2015.

    Directory of Open Access Journals (Sweden)

    Guillermo Sánchez Medina

    2015-06-01

    Full Text Available Nació en Cereté, Córdoba, el 28 de abril de 1925, murió en Bogotá, el 27 de abril de 2015, a la edad de 90 años. Transcurría el año 1950 cuando estudiaba medicina en la Universidad Javeriana en Bogotá. Una tarde casi noche, con el frío sabanero, conocí un personaje cuyo nombre era Arturo Morillo Quiñones, el cual generaría en mí un impacto a diferentes niveles: intelectuales, científicos y humanos, en especial por su manera de ser auténtica, veraz, cálida, con un amplio humor, leal, inteligente, real y brillante. Por aquellos años 1950 establecimos una relación de una profunda amistad. Así vinieron diferentes hechos de nuestras historias personales y el conocimiento de la vida familiar, así como nuestras experiencias. Arturo relataba una serie de reminiscencias vividas de niño por allá en la región del Sinú, el Magdalena, y toda la región llamada de la “Costa Caribe”. Las narraciones que él hacía tenían un tinte de fascinación y despertaban al niño que todos guardamos, y que le seduce esa clase de historias, las cuales oscilaban entre la realidad y la fantasía, lo absurdo y lo lógico, lo primitivo imaginario de sueños despiertos a la realidad, además de una multiplicidad de creencias supersticiones dirigidas por el pensamiento mágico. Personalmente no cesaba de preguntar sobre detalles de los contenidos de las narraciones. Aquí consigno, cómo en los años 1967 volví a leer en textos novelescos estos mismos relatos de Arturo Morillo; ahora escritos por un genio Nobel, Gabriel García Márquez. El doctor Arturo Morillo Quiñones, académico y neurocientífico acabó sus estudios de medicina en 1951 y se graduó en 1954 en la misma Universidad Javeriana; realizó su postgrado en electroencefalografía y neurofisiología en National Institutes of Health, Bethesda, Maryland. Perfeccionó sus estudios de neurofisiología y métodos neurofisiológicos en la investigación de psicofármacos en el Galesburg

  13. D’étranges étrangers. Qui gouverne les correspondants de Jérusalem ?

    Directory of Open Access Journals (Sweden)

    Jérôme Bourdon

    2013-12-01

    Full Text Available Fruit d’une enquête ethnographique auprès des correspondants de la presse étrangère en Israël dans les années 2000, cet article analyse la façon dont les relations des journalistes avec les différents états et nations (y compris les leurs impliqués dans le conflit, affectent leur travail. Il montre comment les journalistes, en fonction de leurs appartenances nationales ou ethniques, sont sommés de prendre parti vis-à-vis de multiples acteurs, ce qui déstabilise la possibilité d’une couverture « neutre » ou « extérieure » acceptable par tous. Cette déstabilisation est analysée à quatre niveaux. 1. Le monde professionnel des journalistes est traversé par ce conflit qui est perçu comme très proche, « quasiment une affaire de politique intérieure », les divisions étant politiques mais aussi nationales, singulièrement entre journalistes américains et européens. 2. Les journalistes sont sommés par les deux parties au conflit, toutes deux très soucieuses de leur image, l’Etat d’Israël recourant aux brimades – ou à la force vis-à-vis des gens d’image palestiniens, les deux partis étant « assoiffés de médias » ; 3. Les journalistes sont mis en cause en raison de leurs origines juive ou arabe, réelles ou supposées ; 4. Enfin des publics nationaux, proisraéliens ou propalestiniens, que le conflit divise, eux-mêmes dotés de moyens de surveillance et de critique nouveaux (satellites, internet, s’en prennent aux correspondants dont le travail ne correspond pas à leur attente.This study is based on an ethnographic investigation of foreign-press correspondentsin Israel/Palestine in the year 2000. It analyzes how the journalists’ work is affected by their relationship to the different states and nations (including their own involved in the Israeli-Palestinian conflict. It shows how journalists, according to their own national or ethnic affiliation, are pressured to take sides by various participants

  14. Commentaire : Comment gérer l'eau qui se raréfie dans les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    14 oct. 2010 ... Les agriculteurs protestèrent contre la perte de sources d'eau qui leur avaient appartenu pendant des générations. La grogne monta et aboutit à la très médiatisée « guerre de l'eau » de Cochabamba en 2000 et aux manifestations massives d'El Alto. À Cochabamba, les escouades anti-émeute et les ...

  15. 47 CFR 15.717 - TVBDs that rely on spectrum sensing.

    Science.gov (United States)

    2010-10-01

    ... Television Band Devices § 15.717 TVBDs that rely on spectrum sensing. (a) Parties may submit applications for... that are identical in electrical characteristics and antenna systems may be certified under the...

  16. Increasing Uncertainty: The Dangers of Relying on Conventional Forces for Nuclear Deterrence

    Science.gov (United States)

    2016-03-14

    72 | Air & Space Power Journal Increasing Uncertainty The Dangers of Relying on Conventional Forces for Nuclear Deterrence Jennifer Bradley To put...relationships and should serve as the cornerstone of US nuclear deterrence policy. Although Russia and China are not identified as adversaries of...exactly what has happened over the past year. The US decision to meet the needs of deterrence by relying less on nuclear weapons and instead devel- oping

  17. ‘Il n’y a que Superman qui porte le slip par-dessus le pantalon’ – les clivées en il n’y a que x qui

    Directory of Open Access Journals (Sweden)

    Karssenberg Lena

    2016-01-01

    Full Text Available Dans cet article, je me propose d’étudier les clivées en il y a qui contiennent la tournure de restriction ne… que, comme Il n’y a que Superman qui porte le slip par-dessus le pantalon (voir Jeanjean 1979 ; Pierrard 1985 ; Léard 1992 ; Furukawa 1996. Je répondrai à deux questions principales, à savoir (i Quelle est la distribution de ces clivées à travers deux registres différents de français ? (ii Quelles sont leurs caractéristiques au niveau de la Structure de l’Information ? Une analyse de corpus nous amène à la conclusion que, premièrement, ce type de clivée est beaucoup plus fréquent en français écrit informel qu’en français écrit journalistique. Deuxièmement, les données de corpus contiennent trois types d’articulations informationnelles, dont seule la première a été mentionnée dans la littérature linguistique sur les phrases en il n’y a que x qui : (i dans les clivées focus – arrière-fond, l’élément clivé (Superman est en focus, alors que l’information exprimée par la phrase relative représente l’arrière-fond. (ii Dans l’articulation ‘à double focus’, (une partie de l’élément clivé et (une partie de la phrase relative sont focalisé(es. Finalement, (iii l’élément clivé peut également être un topique spatio-temporel qui sert d’encadrement de l’information exprimée par la phrase relative. En outre, plusieurs clivées ont une articulation informationnelle ambiguë en raison du fait que l’information nouvelle en discours peut être réinterprétée par l’interlocuteur comme donnée en discours par un processus d’ « accommodation » (Lewis 1979.

  18. The thirty gigahertz instrument receiver for the Q-U-I Joint Tenerife experiment: Concept and experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Villa, Enrique, E-mail: villae@unican.es; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; Fuente, Luisa de la; Artal, Eduardo; Mediavilla, Ángel [Departamento Ingeniería de Comunicaciones, Universidad de Cantabria, Plaza de la Ciencia s/n, Santander 39005 (Spain); Ortiz, David; Casas, Francisco J. [Instituto de Física de Cantabria, Avda. Los Castros s/n, Santander 39005 (Spain); Hoyland, Roger [Instituto de Astrofísica de Canarias, Vía Láctea s/n, La Laguna 38205 (Spain)

    2015-02-15

    This paper presents the analysis, design, and characterization of the thirty gigahertz instrument receiver developed for the Q-U-I Joint Tenerife experiment. The receiver is aimed to obtain polarization data of the cosmic microwave background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. A comprehensive analysis of the theory behind the proposed receiver is presented for a linearly polarized input signal, and the functionality tests have demonstrated adequate results in terms of Stokes parameters, which validate the concept of the receiver based on electronic phase switching.

  19. Systèmes de santé équitables : à qui revient la facture ? | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    24 oct. 2012 ... Les pays à faible revenu, de leur côté, s'efforcent d'offrir à leurs citoyens ce qui est déjà monnaie courante ailleurs : un accès à des services de santé ... à revenu intermédiaire s'appuient sur des sources variées : régimes d'assurance publics et privés, impôts et taxes directs et indirects, frais imposés aux ...

  20. Opinion: Parvenir à une réelle égalité entre les sexes en ce qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    14 nov. 2016 ... L'augmentation des conflits et de la fragilité politique dans plusieurs régions du monde ont exacerbé et enraciné les disparités relatives à la santé des jeunes, particulièrement pour les adolescentes qui font régulièrement face à des obstacles et à une réduction de l'accès aux soins de santé. Lisez l'article ...

  1. The thirty gigahertz instrument receiver for the Q-U-I Joint Tenerife experiment: Concept and experimental results

    International Nuclear Information System (INIS)

    Villa, Enrique; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; Fuente, Luisa de la; Artal, Eduardo; Mediavilla, Ángel; Ortiz, David; Casas, Francisco J.; Hoyland, Roger

    2015-01-01

    This paper presents the analysis, design, and characterization of the thirty gigahertz instrument receiver developed for the Q-U-I Joint Tenerife experiment. The receiver is aimed to obtain polarization data of the cosmic microwave background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. A comprehensive analysis of the theory behind the proposed receiver is presented for a linearly polarized input signal, and the functionality tests have demonstrated adequate results in terms of Stokes parameters, which validate the concept of the receiver based on electronic phase switching

  2. 76 FR 69545 - Conditions and Requirements for Relying on Component Part Testing or Certification, or Another...

    Science.gov (United States)

    2011-11-08

    ... the final rule to incorporate the concept that a finished product certifier may rely upon finished... revised, on our own initiative, the final rule to incorporate the concept that a finished product... Vol. 76 Tuesday, No. 216 November 8, 2011 Part IV Consumer Product Safety Commission 16 CFR Parts...

  3. Cortical control of object-specific grasp relies on adjustments of both activity and effective connectivity

    DEFF Research Database (Denmark)

    Tia, Banty; Takemi, Mitsuaki; Kosugi, Akito

    2017-01-01

    The cortical mechanisms of grasping have been extensively studied in macaques and humans. Here, we investigated whether common marmosets could rely on similar mechanisms despite striking differences in manual dexterity. Two common marmosets were trained to grasp-and-pull three objects eliciting d...

  4. 77 FR 70117 - Purchase of Certain Debt Securities by Business and Industrial Development Companies Relying on...

    Science.gov (United States)

    2012-11-23

    ... 3235-AL02 Purchase of Certain Debt Securities by Business and Industrial Development Companies Relying... securities; (B) is engaged or proposes to engage in the business of issuing face-amount certificates of the... business of issuing redeemable securities, the operations of which are subject to regulation by the State...

  5. Polarimetric receiver in the forty gigahertz band: new instrument for the Q-U-I joint Tenerife experiment

    Science.gov (United States)

    Villa, Enrique; Cano, Juan L.; Aja, Beatriz; Terán, J. Vicente; de la Fuente, Luisa; Mediavilla, Ángel; Artal, Eduardo

    2018-03-01

    This paper describes the analysis, design and characterization of a polarimetric receiver developed for covering the 35 to 47 GHz frequency band in the new instrument aimed at completing the ground-based Q-U-I Joint Tenerife Experiment. This experiment is designed to measure polarization in the Cosmic Microwave Background. The described high frequency instrument is a HEMT-based array composed of 29 pixels. A thorough analysis of the behaviour of the proposed receiver, based on electronic phase switching, is presented for a noise-like linearly polarized input signal, obtaining simultaneously I, Q and U Stokes parameters of the input signal. Wideband subsystems are designed, assembled and characterized for the polarimeter. Their performances are described showing appropriate results within the 35-to-47 GHz frequency band. Functionality tests are performed at room and cryogenic temperatures with adequate results for both temperature conditions, which validate the receiver concept and performance.

  6. De l'injure en pays maure ou « qui ne loue pas critique »

    Directory of Open Access Journals (Sweden)

    Catherine Taine-Cheikh

    2009-05-01

    Full Text Available Catherine Taine-Cheikh, qui s'intéresse au phénomène de l'injure dans la société arabophone de Mauritanie, commence par étudier les différents termes du dialecte hassâniyya qui relèvent de ce champ sémantique. Elle s'attache ensuite à montrer l'importance et la complexité de l'« effet injure », dans cette société fortement imprégnée par les valeurs de l'honneur où non seulement la critique mais aussi la louange peuvent apparaître comme des manifestations de l'injure. Passant en revue diverses situations empruntées à la vie quotidienne ou puisées dans des matériaux littéraires (écrits et surtout oraux, l'auteur relève diverses stratégies adoptées, soit par les injurieurs, soit par les injuriaires, pour tenter de maîtriser les effets des mots (ou gestes « déplacés ». Bien que le problème du contrôle de soi semble presque toujours primordial, la gestion de l'injure laisse apparaître une différenciation importante en fonction du sexe et du statut relatif des acteurs sociaux concernés.

  7. La langue qui fâche : quand la norme qui lâche suscite l’insulte When norms loosen, abuse pops up and language offends

    Directory of Open Access Journals (Sweden)

    Laurence Rosier

    2012-04-01

    Full Text Available Dans cet article nous proposons d’étudier les titres de groupes facebook dont les dénominations visent à dévaloriser les locuteurs qui ne maîtrisent pas la norme linguistique. On verra que lorsqu’il s’agit de la maîtrise de la langue, les internautes stigmatisent les accrocs à la norme et peuvent adopter des attitudes d’une extrême violence : les fautes sont considérées comme insultantes pour ceux qui maîtrisent la langue. La violence verbale observée trouverait sa légitimité dans le fait qu’il y a « outrage à la langue » : les locuteurs « censeurs » seraient dès lors autorisés à produire un discours violent « outrageant » vis-à-vis des faiseurs de fautes. Nos analyses montreront que l’appel au regroupement contre les « locuteurs-fauteurs » repose sur une doxa commune (l’importance de la maîtrise de la langue plutôt que sur une argumentation explicite. Nous verrons comment se manifeste linguistiquement la violence verbale dans notre corpus (phénomènes énonciatifs, processus interactionnel,… et où se situent les dénominations facebookiennes sur une échelle graduée de violence.In this article, we study the names of facebook groups which aim at reducing the value of the speakers who do not control linguistic norms. The internet users stigmatize tears in norm and can adopt attitudes of an extreme violence: errors are considered as insulting for those who master the language. The “offense to the language” is supposed to legitimize verbal violence: the speakers “censors” would since then be authorized to produce a violent speech "offending" in relation to the miracle-workers of errors. Our analyses will show that the call to grouping against the “speakers-troublemakers” rests on a common doxa (the importance of the workmanship of the language rather than on a definite argumentation. We will examine the various manifestations of verbal violence (on the level on enunciation

  8. ¿Quién es la víctima y quién el agresor en la violencia física entre parejas?: estudio epidemiológico en siete ciudades del Perú

    Directory of Open Access Journals (Sweden)

    Fabián Fiestas

    Full Text Available Objetivos. Identificar factores asociados con la probabilidad de ser víctima o agresor en violencia física entre parejas. Materiales y métodos. Se analizó la base de datos de una encuesta poblacional aplicada en siete ciudades de Perú (Lima, Arequipa, Huamanga, Trujillo, Cusco, Callao y Maynas. Participaron 6399 hombres y mujeres, de los cuales 3909 refirieron vivir en pareja al momento de la entrevista. Se empleó regresión logística univariada y multivariada para identificar factores asociados con cualquiera de los roles, víctima o agresor. El alfa establecido fue 0,01. Resultados. La probabilidad de ser víctima o agresor en la violencia física entre parejas fue similar para ambos sexos (p>0,01, e independiente del tiempo de convivencia. La exposición a la violencia en la niñez, tener una actitud favorable a la violencia, ser menor de 45 años, el consumo excesivo de alcohol, tener educación superior incompleta y tener un ingreso familiar de menos de 750 USD son factores asociados tanto a ser víctima como a ser agresor. Geográficamente, Cusco es la ciudad en que se puede encontrar con mayor probabilidad personas que ejercen violencia física contra la pareja o son víctimas de ella. El valor fue p<0,001 para la mayoría de estas asociaciones. Conclusiones. El patrón de características que predice quién es la víctima, es muy similar al que predice quién es el agresor en los casos de violencia física contra la pareja. El sexo y los años de convivencia no son predictivos para ninguno de los roles violencia física contra la pareja.

  9. ¿Quién es la víctima y quién el agresor en la violencia física entre parejas? Estudio epidemiológico en siete ciudades del Perú

    Directory of Open Access Journals (Sweden)

    Fabián Fiestas

    Full Text Available Objetivos. Identificar factores asociados con la probabilidad de ser víctima o agresor en violencia física entre parejas. Materiales y métodos. Se analizó la base de datos de una encuesta poblacional aplicada en siete ciudades de Perú (Lima, Arequipa, Huamanga, Trujillo, Cusco, Callao y Maynas. Participaron 6399 hombres y mujeres, de los cuales 3909 refirieron vivir en pareja al momento de la entrevista. Se empleó regresión logística univariada y multivariada para identificar factores asociados con cualquiera de los roles, víctima o agresor. El alfa establecido fue 0,01. Resultados. La probabilidad de ser víctima o agresor en la violencia física entre parejas fue similar para ambos sexos (p>0,01, e independiente del tiempo de convivencia. La exposición a la violencia en la niñez, tener una actitud favorable a la violencia, ser menor de 45 años, el consumo excesivo de alcohol, tener educación superior incompleta y tener un ingreso familiar de menos de 750 USD son factores asociados tanto a ser víctima como a ser agresor. Geográficamente, Cusco es la ciudad en que se puede encontrar con mayor probabilidad personas que ejercen violencia física contra la pareja o son víctimas de ella. El valor fue p<0,001 para la mayoría de estas asociaciones. Conclusiones. El patrón de características que predice quién es la víctima, es muy similar al que predice quién es el agresor en los casos de violencia física contra la pareja. El sexo y los años de convivencia no son predictivos para ninguno de los roles violencia física contra la pareja

  10. Qui attrapera le Higgs?

    CERN Multimedia

    Colas, Paul

    2003-01-01

    The Higgs boson was theoretically created about 40 years ago by a Scott Peter Higgs who wanted to explain why some particles get a mass. Since then the Higgs boson has taken consistency and has become an important point of the standard model theory. Its experimental discovery would be a milestone of modern physics. The search for the Higgs boson is an international challenge that takes place around 2 huge machines: the Tevatron near Chicago and the LHC (large hadron collider) that is being built in CERN. The Tevatron is in fact the upgrading of an old particle accelerator, it is a proton collider and its narrow range of energy is compensated by a low background noise. On the other hand the LHC will begin operating only in 2007 and its full power will be reached a few years later, the energy available to create particles will be then 7 times higher than for the Tevatron. Both machines have chance of succeeding by being the first to detect the Higgs boson. Time plays in favor of the Tevatron but in any case if ...

  11. Qui Exanimis Nascitur?

    DEFF Research Database (Denmark)

    Pedersen, Morten Jarlbæk

    2017-01-01

    Better regulation is of grave importance to the European Union as this is seen as a way of obtaining output legitimacy. To achieve this, the European Commission has established a so-called REFIT Stakeholder Platform where stakeholders’ proposals for more effective and efficient EU law are discussed....... The central premise for this meta-regulatory instrument is depoliticisation of the REFIT program and the whole better regulation agenda. To ensure this, the European Commission plays a crucial gatekeeping role by only granting access for proposals that echo that premise and by securing depoliticised...

  12. Qui Exanimis Nascitur?

    DEFF Research Database (Denmark)

    Jarlbæk Pedersen, Morten

    2017-01-01

    Better regulation is of grave importance to the European Union, as it is seen as a way of obtaining output legitimacy. To achieve this, the European Commission has established a so-called REFIT Stakeholder Platform where stakeholders' proposals for more effective and efficient EU law are discussed....... The central premise for this meta-regulatory instrument is depoliticisation of the REFIT program and the whole better regulation agenda. To ensure this, the European Commission plays a crucial gatekeeping role by only granting access for proposals that echo that premise and by securing depoliticised...

  13. Logical Characterisation of Concept Transformations from Human into Machine relying on Predicate Logic

    DEFF Research Database (Denmark)

    Badie, Farshad

    2016-01-01

    Providing more human-like concept learning in machines has always been one of the most significant goals of machine learning paradigms and of human-machine interaction techniques. This article attempts to provide a logical specification of conceptual mappings from humans’ minds into machines......’ knowledge bases. I will focus on the representation of the mappings (transformations) relying on First-Order Predicate Logic. Additionally, the structure of concepts in the common ground between humans and machines will be analysed. It seems quite necessary to pay attention to the philosophy...

  14. Regulated Medicare Advantage And Marketplace Individual Health Insurance Markets Rely On Insurer Competition.

    Science.gov (United States)

    Frank, Richard G; McGuire, Thomas G

    2017-09-01

    Two important individual health insurance markets-Medicare Advantage and the Marketplaces-are tightly regulated but rely on competition among insurers to supply and price health insurance products. Many local health insurance markets have little competition, which increases prices to consumers. Furthermore, both markets are highly subsidized in ways that can exacerbate the impact of market power-that is, the ability to set price above cost-on health insurance prices. Policy makers need to foster robust competition in both sectors and avoid designing subsidies that make the market-power problem worse. Project HOPE—The People-to-People Health Foundation, Inc.

  15. Anemonefishes rely on visual and chemical cues to correctly identify conspecifics

    Science.gov (United States)

    Johnston, Nicole K.; Dixson, Danielle L.

    2017-09-01

    Organisms rely on sensory cues to interpret their environment and make important life-history decisions. Accurate recognition is of particular importance in diverse reef environments. Most evidence on the use of sensory cues focuses on those used in predator avoidance or habitat recognition, with little information on their role in conspecific recognition. Yet conspecific recognition is essential for life-history decisions including settlement, mate choice, and dominance interactions. Using a sensory manipulated tank and a two-chamber choice flume, anemonefish conspecific response was measured in the presence and absence of chemical and/or visual cues. Experiments were then repeated in the presence or absence of two heterospecific species to evaluate whether a heterospecific fish altered the conspecific response. Anemonefishes responded to both the visual and chemical cues of conspecifics, but relied on the combination of the two cues to recognize conspecifics inside the sensory manipulated tank. These results contrast previous studies focusing on predator detection where anemonefishes were found to compensate for the loss of one sensory cue (chemical) by utilizing a second cue (visual). This lack of sensory compensation may impact the ability of anemonefishes to acclimate to changing reef environments in the future.

  16. Hummingbirds rely on both paracellular and carrier-mediated intestinal glucose absorption to fuel high metabolism

    Science.gov (United States)

    McWhorter, Todd J; Bakken, Bradley Hartman; Karasov, William H; del Rio, Carlos Martínez

    2005-01-01

    Twenty years ago, the highest active glucose transport rate and lowest passive glucose permeability in vertebrates were reported in Rufous and Anna's hummingbirds (Selasphorus rufus, Calypte anna). These first measurements of intestinal nutrient absorption in nectarivores provided an unprecedented physiological foundation for understanding their foraging ecology. They showed that physiological processes are determinants of feeding behaviour. The conclusion that active, mediated transport accounts for essentially all glucose absorption in hummingbirds influenced two decades of subsequent research on the digestive physiology and nutritional ecology of nectarivores. Here, we report new findings demonstrating that the passive permeability of hummingbird intestines to glucose is much higher than previously reported, suggesting that not all sugar uptake is mediated. Even while possessing the highest active glucose transport rates measured in vertebrates, hummingbirds must rely partially on passive non-mediated intestinal nutrient absorption to meet their high mass-specific metabolic demands. PMID:17148346

  17. Episodic Memory Retrieval Functionally Relies on Very Rapid Reactivation of Sensory Information.

    Science.gov (United States)

    Waldhauser, Gerd T; Braun, Verena; Hanslmayr, Simon

    2016-01-06

    Episodic memory retrieval is assumed to rely on the rapid reactivation of sensory information that was present during encoding, a process termed "ecphory." We investigated the functional relevance of this scarcely understood process in two experiments in human participants. We presented stimuli to the left or right of fixation at encoding, followed by an episodic memory test with centrally presented retrieval cues. This allowed us to track the reactivation of lateralized sensory memory traces during retrieval. Successful episodic retrieval led to a very early (∼100-200 ms) reactivation of lateralized alpha/beta (10-25 Hz) electroencephalographic (EEG) power decreases in the visual cortex contralateral to the visual field at encoding. Applying rhythmic transcranial magnetic stimulation to interfere with early retrieval processing in the visual cortex led to decreased episodic memory performance specifically for items encoded in the visual field contralateral to the site of stimulation. These results demonstrate, for the first time, that episodic memory functionally relies on very rapid reactivation of sensory information. Remembering personal experiences requires a "mental time travel" to revisit sensory information perceived in the past. This process is typically described as a controlled, relatively slow process. However, by using electroencephalography to measure neural activity with a high time resolution, we show that such episodic retrieval entails a very rapid reactivation of sensory brain areas. Using transcranial magnetic stimulation to alter brain function during retrieval revealed that this early sensory reactivation is causally relevant for conscious remembering. These results give first neural evidence for a functional, preconscious component of episodic remembering. This provides new insight into the nature of human memory and may help in the understanding of psychiatric conditions that involve the automatic intrusion of unwanted memories. Copyright

  18. Cochlear implant users rely on tempo rather than on pitch information during perception of musical emotion.

    Science.gov (United States)

    Caldwell, Meredith; Rankin, Summer K; Jiradejvong, Patpong; Carver, Courtney; Limb, Charles J

    2015-09-01

    The purpose of this study was to investigate the extent to which cochlear implant (CI) users rely on tempo and mode in perception of musical emotion when compared with normal hearing (NH) individuals. A test battery of novel four-bar melodies was created and adapted to four permutations with alterations of tonality (major vs. minor) and tempo (presto vs. largo), resulting in non-ambiguous (major key/fast tempo and minor key/slow tempo) and ambiguous (major key/slow tempo, and minor key/fast tempo) musical stimuli. Both CI and NH participants listened to each clip and provided emotional ratings on a Likert scale of +5 (happy) to -5 (sad). A three-way ANOVA demonstrated an overall effect for tempo in both groups, and an overall effect for mode in the NH group. The CI group rated stimuli of the same tempo similarly, regardless of changes in mode, whereas the NH group did not. A subgroup analysis indicated the same effects in both musician and non-musician CI users and NH listeners. The results suggest that the CI group relied more heavily on tempo than mode in making musical emotion decisions. The subgroup analysis further suggests that level of musical training did not significantly impact this finding. CI users weigh temporal cues more heavily than pitch cues in inferring musical emotion. These findings highlight the significant disadvantage of CI users in comparison with NH listeners for music perception, particularly during recognition of musical emotion, a critically important feature of music.

  19. Defining the buffering process by a triprotic acid without relying on Stewart-electroneutrality considerations.

    Science.gov (United States)

    Nguyen, Minhtri K; Kao, Liyo; Kurtz, Ira

    2011-08-17

    Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the acid as well as to OH- ions that are derived from the auto-ionization of H2O. In quantifying the buffering process of a triprotic acid, one must define the partitioning of H+ among the three states of the acid and also the OH- ions in solution in order to predict the equilibrium pH value. However, previous quantitative approaches that model triprotic acid titration behaviour and used to predict the equilibrium pH rely on the mathematical convenience of electroneutrality/charge balance considerations. This fact has caused confusion in the literature, and has led to the assumption that charge balance/electroneutrality is a causal factor in modulating proton buffering (Stewart formulation). However, as we have previously shown, although charge balance can be used mathematically as a convenient tool in deriving various formulae, electroneutrality per se is not a fundamental physicochemical parameter that is mechanistically involved in the underlying buffering and proton transfer reactions. The lack of distinction between a mathematical tool, and a fundamental physicochemical parameter is in part a reason for the current debate regarding the Stewart formulation of acid-base analysis. We therefore posed the following question: Is it possible to generate an equation that defines and predicts the buffering of a triprotic acid that is based only on H+ partitioning without incorporating electroneutrality in the derivation? Towards this goal, we derived our new equation utilizing: 1) partitioning of H+ buffering; 2) conservation of mass; and 3) acid-base equilibria. In validating this model, we compared the predicted equilibrium pH with the measured pH of an aqueous solution consisting of Na2HPO4 to which HCl was added. The measured pH values were in excellent agreement

  20. Defining the buffering process by a triprotic acid without relying on stewart-electroneutrality considerations

    Directory of Open Access Journals (Sweden)

    Kao Liyo

    2011-08-01

    Full Text Available Abstract Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the acid as well as to OH- ions that are derived from the auto-ionization of H2O. In quantifying the buffering process of a triprotic acid, one must define the partitioning of H+ among the three states of the acid and also the OH- ions in solution in order to predict the equilibrium pH value. However, previous quantitative approaches that model triprotic acid titration behaviour and used to predict the equilibrium pH rely on the mathematical convenience of electroneutrality/charge balance considerations. This fact has caused confusion in the literature, and has led to the assumption that charge balance/electroneutrality is a causal factor in modulating proton buffering (Stewart formulation. However, as we have previously shown, although charge balance can be used mathematically as a convenient tool in deriving various formulae, electroneutrality per se is not a fundamental physicochemical parameter that is mechanistically involved in the underlying buffering and proton transfer reactions. The lack of distinction between a mathematical tool, and a fundamental physicochemical parameter is in part a reason for the current debate regarding the Stewart formulation of acid-base analysis. We therefore posed the following question: Is it possible to generate an equation that defines and predicts the buffering of a triprotic acid that is based only on H+ partitioning without incorporating electroneutrality in the derivation? Towards this goal, we derived our new equation utilizing: 1 partitioning of H+ buffering; 2 conservation of mass; and 3 acid-base equilibria. In validating this model, we compared the predicted equilibrium pH with the measured pH of an aqueous solution consisting of Na2HPO4 to which HCl was added. The measured pH values

  1. Defining the buffering process by a triprotic acid without relying on stewart-electroneutrality considerations

    Science.gov (United States)

    2011-01-01

    Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the acid as well as to OH- ions that are derived from the auto-ionization of H2O. In quantifying the buffering process of a triprotic acid, one must define the partitioning of H+ among the three states of the acid and also the OH- ions in solution in order to predict the equilibrium pH value. However, previous quantitative approaches that model triprotic acid titration behaviour and used to predict the equilibrium pH rely on the mathematical convenience of electroneutrality/charge balance considerations. This fact has caused confusion in the literature, and has led to the assumption that charge balance/electroneutrality is a causal factor in modulating proton buffering (Stewart formulation). However, as we have previously shown, although charge balance can be used mathematically as a convenient tool in deriving various formulae, electroneutrality per se is not a fundamental physicochemical parameter that is mechanistically involved in the underlying buffering and proton transfer reactions. The lack of distinction between a mathematical tool, and a fundamental physicochemical parameter is in part a reason for the current debate regarding the Stewart formulation of acid-base analysis. We therefore posed the following question: Is it possible to generate an equation that defines and predicts the buffering of a triprotic acid that is based only on H+ partitioning without incorporating electroneutrality in the derivation? Towards this goal, we derived our new equation utilizing: 1) partitioning of H+ buffering; 2) conservation of mass; and 3) acid-base equilibria. In validating this model, we compared the predicted equilibrium pH with the measured pH of an aqueous solution consisting of Na2HPO4 to which HCl was added. The measured pH values were in excellent agreement

  2. 12 CFR 221.117 - When bank in “good faith” has not relied on stock as collateral.

    Science.gov (United States)

    2010-01-01

    ... bank in “good faith” has not relied on stock as collateral. (a) The Board has received questions... “indirectly secured” by stock as indicated by the phrase, “if the lender, in good faith, has not relied upon...

  3. The Long-Term Multicenter Observational Study of Dabigatran Treatment in Patients With Atrial Fibrillation (RELY-ABLE) Study

    DEFF Research Database (Denmark)

    Connolly, S. J.; Wallentin, L.; Ezekowitz, M. D.

    2013-01-01

    . There is a need for longer-term follow-up of patients on dabigatran and for further data comparing the 2 dabigatran doses. Methods and Results Patients randomly assigned to dabigatran in RE-LY were eligible for the Long-term Multicenter Extension of Dabigatran Treatment in Patients with Atrial Fibrillation (RELY...

  4. Frugivorous bats maintain functional habitat connectivity in agricultural landscapes but rely strongly on natural forest fragments.

    Science.gov (United States)

    Ripperger, Simon P; Kalko, Elisabeth K V; Rodríguez-Herrera, Bernal; Mayer, Frieder; Tschapka, Marco

    2015-01-01

    Anthropogenic changes in land use threaten biodiversity and ecosystem functioning by the conversion of natural habitat into agricultural mosaic landscapes, often with drastic consequences for the associated fauna. The first step in the development of efficient conservation plans is to understand movement of animals through complex habitat mosaics. Therefore, we studied ranging behavior and habitat use in Dermanura watsoni (Phyllostomidae), a frugivorous bat species that is a valuable seed disperser in degraded ecosystems. Radio-tracking of sixteen bats showed that the animals strongly rely on natural forest. Day roosts were exclusively located within mature forest fragments. Selection ratios showed that the bats foraged selectively within the available habitat and positively selected natural forest. However, larger daily ranges were associated with higher use of degraded habitats. Home range geometry and composition of focal foraging areas indicated that wider ranging bats performed directional foraging bouts from natural to degraded forest sites traversing the matrix over distances of up to three hundred meters. This behavior demonstrates the potential of frugivorous bats to functionally connect fragmented areas by providing ecosystem services between natural and degraded sites, and highlights the need for conservation of natural habitat patches within agricultural landscapes that meet the roosting requirements of bats.

  5. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation

    Science.gov (United States)

    Lakkaraju, Asvin K. K.; Thankappan, Ratheeshkumar; Mary, Camille; Garrison, Jennifer L.; Taunton, Jack; Strub, Katharina

    2012-01-01

    Mammalian cells secrete a large number of small proteins, but their mode of translocation into the endoplasmic reticulum is not fully understood. Cotranslational translocation was expected to be inefficient due to the small time window for signal sequence recognition by the signal recognition particle (SRP). Impairing the SRP pathway and reducing cellular levels of the translocon component Sec62 by RNA interference, we found an alternate, Sec62-dependent translocation path in mammalian cells required for the efficient translocation of small proteins with N-terminal signal sequences. The Sec62-dependent translocation occurs posttranslationally via the Sec61 translocon and requires ATP. We classified preproteins into three groups: 1) those that comprise ≤100 amino acids are strongly dependent on Sec62 for efficient translocation; 2) those in the size range of 120–160 amino acids use the SRP pathway, albeit inefficiently, and therefore rely on Sec62 for efficient translocation; and 3) those larger than 160 amino acids depend on the SRP pathway to preserve a transient translocation competence independent of Sec62. Thus, unlike in yeast, the Sec62-dependent translocation pathway in mammalian cells serves mainly as a fail-safe mechanism to ensure efficient secretion of small proteins and provides cells with an opportunity to regulate secretion of small proteins independent of the SRP pathway. PMID:22648169

  6. Regulatory theory: commercially sustainable markets rely upon satisfying the public interest in obtaining credible goods.

    Science.gov (United States)

    Warren-Jones, Amanda

    2017-10-01

    Regulatory theory is premised on the failure of markets, prompting a focus on regulators and industry from economic perspectives. This article argues that overlooking the public interest in the sustainability of commercial markets risks markets failing completely. This point is exemplified through health care markets - meeting an essential need - and focuses upon innovative medicines as the most desired products in that market. If this seemingly invulnerable market risks failure, there is a pressing need to consider the public interest in sustainable markets within regulatory literature and practice. Innovative medicines are credence goods, meaning that the sustainability of the market fundamentally relies upon the public trusting regulators to vouch for product quality. Yet, quality is being eroded by patent bodies focused on economic benefits from market growth, rather than ensuring innovatory value. Remunerative bodies are not funding medicines relative to market value, and market authorisation bodies are not vouching for robust safety standards or confining market entry to products for 'unmet medical need'. Arguably, this failure to assure quality heightens the risk of the market failing where it cannot be substituted by the reputation or credibility of providers of goods and/or information such as health care professionals/institutions, patient groups or industry.

  7. Quality of record linkage in a highly automated cancer registry that relies on encrypted identity data

    Directory of Open Access Journals (Sweden)

    Schmidtmann, Irene

    2016-06-01

    Full Text Available Objectives: In the absence of unique ID numbers, cancer and other registries in Germany and elsewhere rely on identity data to link records pertaining to the same patient. These data are often encrypted to ensure privacy. Some record linkage errors unavoidably occur. These errors were quantified for the cancer registry of North Rhine Westphalia which uses encrypted identity data. Methods: A sample of records was drawn from the registry, record linkage information was included. In parallel, plain text data for these records were retrieved to generate a gold standard. Record linkage error frequencies in the cancer registry were determined by comparison of the results of the routine linkage with the gold standard. Error rates were projected to larger registries.Results: In the sample studied, the homonym error rate was 0.015%; the synonym error rate was 0.2%. The F-measure was 0.9921. Projection to larger databases indicated that for a realistic development the homonym error rate will be around 1%, the synonym error rate around 2%.Conclusion: Observed error rates are low. This shows that effective methods to standardize and improve the quality of the input data have been implemented. This is crucial to keep error rates low when the registry’s database grows. The planned inclusion of unique health insurance numbers is likely to further improve record linkage quality. Cancer registration entirely based on electronic notification of records can process large amounts of data with high quality of record linkage.

  8. Pneumococcal Competence Coordination Relies on a Cell-Contact Sensing Mechanism.

    Directory of Open Access Journals (Sweden)

    Marc Prudhomme

    2016-06-01

    Full Text Available Bacteria have evolved various inducible genetic programs to face many types of stress that challenge their growth and survival. Competence is one such program. It enables genetic transformation, a major horizontal gene transfer process. Competence development in liquid cultures of Streptococcus pneumoniae is synchronized within the whole cell population. This collective behavior is known to depend on an exported signaling Competence Stimulating Peptide (CSP, whose action generates a positive feedback loop. However, it is unclear how this CSP-dependent population switch is coordinated. By monitoring spontaneous competence development in real time during growth of four distinct pneumococcal lineages, we have found that competence shift in the population relies on a self-activated cell fraction that arises via a growth time-dependent mechanism. We demonstrate that CSP remains bound to cells during this event, and conclude that the rate of competence development corresponds to the propagation of competence by contact between activated and quiescent cells. We validated this two-step cell-contact sensing mechanism by measuring competence development during co-cultivation of strains with altered capacity to produce or respond to CSP. Finally, we found that the membrane protein ComD retains the CSP, limiting its free diffusion in the medium. We propose that competence initiator cells originate stochastically in response to stress, to form a distinct subpopulation that then transmits the CSP by cell-cell contact.

  9. Frugivorous bats maintain functional habitat connectivity in agricultural landscapes but rely strongly on natural forest fragments.

    Directory of Open Access Journals (Sweden)

    Simon P Ripperger

    Full Text Available Anthropogenic changes in land use threaten biodiversity and ecosystem functioning by the conversion of natural habitat into agricultural mosaic landscapes, often with drastic consequences for the associated fauna. The first step in the development of efficient conservation plans is to understand movement of animals through complex habitat mosaics. Therefore, we studied ranging behavior and habitat use in Dermanura watsoni (Phyllostomidae, a frugivorous bat species that is a valuable seed disperser in degraded ecosystems. Radio-tracking of sixteen bats showed that the animals strongly rely on natural forest. Day roosts were exclusively located within mature forest fragments. Selection ratios showed that the bats foraged selectively within the available habitat and positively selected natural forest. However, larger daily ranges were associated with higher use of degraded habitats. Home range geometry and composition of focal foraging areas indicated that wider ranging bats performed directional foraging bouts from natural to degraded forest sites traversing the matrix over distances of up to three hundred meters. This behavior demonstrates the potential of frugivorous bats to functionally connect fragmented areas by providing ecosystem services between natural and degraded sites, and highlights the need for conservation of natural habitat patches within agricultural landscapes that meet the roosting requirements of bats.

  10. Toward a Better Nutritional Aiding in Disasters: Relying on Lessons Learned during the Bam Earthquake.

    Science.gov (United States)

    Nekouie Moghadam, Mahmoud; Amiresmaieli, Mohammadreza; Hassibi, Mohammad; Doostan, Farideh; Khosravi, Sajad

    2017-08-01

    Introduction Examining various problems in the aftermath of disasters is very important to the disaster victims. Managing and coordinating food supply and its distribution among the victims is one of the most important problems after an earthquake. Therefore, the purpose of this study was to recognize problems and experiences in the field of nutritional aiding during an earthquake. This qualitative study was of phenomenological type. Using the purposive sampling method, 10 people who had experienced nutritional aiding during the Bam Earthquake (Iran; 2003) were interviewed. Colaizzi's method of analysis was used to analyze interview data. The findings of this study identified four main categories and 19 sub-categories concerning challenges in the nutritional aiding during the Bam Earthquake. The main topics included managerial, aiding, infrastructural, and administrative problems. The major problems in nutritional aiding include lack of prediction and development of a specific program of suitable nutritional pattern and nutritional assessment of the victims in critical conditions. Forming specialized teams, educating team members about nutrition, and making use of experts' knowledge are the most important steps to resolve these problems in the critical conditions; these measures are the duties of the relevant authorities. Nekouie Moghadam M , Amiresmaieli M , Hassibi M , Doostan F , Khosravi S . Toward a better nutritional aiding in disasters: relying on lessons learned during the Bam Earthquake. Prehosp Disaster Med. 2017;32(4):382-386.

  11. The Low Pitch of High-Frequency Complex Tones Relies on Temporal Fine Structure Information

    DEFF Research Database (Denmark)

    Santurette, Sébastien; Dau, Torsten

    2010-01-01

    High-frequency complex tones containing only unresolved harmonic components with a frequency spacing Δf usually evoke a low pitch equal to Δf. However, for inharmonic components, the low pitch is often found to deviate slightly from Δf. Whether this pitch shift relies exclusively on temporal fine...... structure (TFS) cues has been a matter of debate. It is also controversial up to which frequency TFS information remains available, and to what extent envelope cues become dominant as frequency increases. Using a pitch-matching paradigm, this study investigated whether the pitch of transposed tones.......5]. All stimuli were presented at 50 dB SPL in broadband pink-noise (13.5 dB/Hz at 1 kHz), and 40 matches per condition were obtained. For fenv = fc/11.5, the results favored hypothesis A for all values of fc, indicating that TFS cues are available and used for pitch extraction, up to at least 7 k...

  12. Mouse V1 population correlates of visual detection rely on heterogeneity within neuronal response patterns

    Science.gov (United States)

    Montijn, Jorrit S; Goltstein, Pieter M; Pennartz, Cyriel MA

    2015-01-01

    Previous studies have demonstrated the importance of the primary sensory cortex for the detection, discrimination, and awareness of visual stimuli, but it is unknown how neuronal populations in this area process detected and undetected stimuli differently. Critical differences may reside in the mean strength of responses to visual stimuli, as reflected in bulk signals detectable in functional magnetic resonance imaging, electro-encephalogram, or magnetoencephalography studies, or may be more subtly composed of differentiated activity of individual sensory neurons. Quantifying single-cell Ca2+ responses to visual stimuli recorded with in vivo two-photon imaging, we found that visual detection correlates more strongly with population response heterogeneity rather than overall response strength. Moreover, neuronal populations showed consistencies in activation patterns across temporally spaced trials in association with hit responses, but not during nondetections. Contrary to models relying on temporally stable networks or bulk signaling, these results suggest that detection depends on transient differentiation in neuronal activity within cortical populations. DOI: http://dx.doi.org/10.7554/eLife.10163.001 PMID:26646184

  13. Unparalleled sample treatment throughput for proteomics workflows relying on ultrasonic energy.

    Science.gov (United States)

    Jorge, Susana; Araújo, J E; Pimentel-Santos, F M; Branco, Jaime C; Santos, Hugo M; Lodeiro, Carlos; Capelo, J L

    2018-02-01

    We report on the new microplate horn ultrasonic device as a powerful tool to speed proteomics workflows with unparalleled throughput. 96 complex proteomes were digested at the same time in 4min. Variables such as ultrasonication time, ultrasonication amplitude, and protein to enzyme ratio were optimized. The "classic" method relying on overnight protein digestion (12h) and the sonoreactor-based method were also employed for comparative purposes. We found the protein digestion efficiency homogeneously distributed in the entire microplate horn surface using the following conditions: 4min sonication time and 25% amplitude. Using this approach, patients with lymphoma and myeloma were classified using principal component analysis and a 2D gel-mass spectrometry based approach. Furthermore, we demonstrate the excellent performance by using MALDI-mass spectrometry based profiling as a fast way to classify patients with rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. Finally, the speed and simplicity of this method were demonstrated by clustering 90 patients with knee osteoarthritis disease (30), with a prosthesis (30, control group) and healthy individuals (30) with no history of joint disease. Overall, the new approach allows profiling a disease in just one week while allows to match the minimalism rules as outlined by Halls. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Laser-induced breakdown spectroscopy and chemometrics for classification of toys relying on toxic elements

    International Nuclear Information System (INIS)

    Godoi, Quienly; Leme, Flavio O.; Trevizan, Lilian C.; Pereira Filho, Edenir R.; Rufini, Iolanda A.; Santos, Dario; Krug, Francisco J.

    2011-01-01

    Quality control of toys for avoiding children exposure to potentially toxic elements is of utmost relevance and it is a common requirement in national and/or international norms for health and safety reasons. Laser-induced breakdown spectroscopy (LIBS) was recently evaluated at authors' laboratory for direct analysis of plastic toys and one of the main difficulties for the determination of Cd, Cr and Pb was the variety of mixtures and types of polymers. As most norms rely on migration (lixiviation) protocols, chemometric classification models from LIBS spectra were tested for sampling toys that present potential risk of Cd, Cr and Pb contamination. The classification models were generated from the emission spectra of 51 polymeric toys and by using Partial Least Squares - Discriminant Analysis (PLS-DA), Soft Independent Modeling of Class Analogy (SIMCA) and K-Nearest Neighbor (KNN). The classification models and validations were carried out with 40 and 11 test samples, respectively. Best results were obtained when KNN was used, with corrected predictions varying from 95% for Cd to 100% for Cr and Pb.

  15. Learning Similar Actions by Reinforcement or Sensory-Prediction Errors Rely on Distinct Physiological Mechanisms.

    Science.gov (United States)

    Uehara, Shintaro; Mawase, Firas; Celnik, Pablo

    2017-09-14

    Humans can acquire knowledge of new motor behavior via different forms of learning. The two forms most commonly studied have been the development of internal models based on sensory-prediction errors (error-based learning) and success-based feedback (reinforcement learning). Human behavioral studies suggest these are distinct learning processes, though the neurophysiological mechanisms that are involved have not been characterized. Here, we evaluated physiological markers from the cerebellum and the primary motor cortex (M1) using noninvasive brain stimulations while healthy participants trained finger-reaching tasks. We manipulated the extent to which subjects rely on error-based or reinforcement by providing either vector or binary feedback about task performance. Our results demonstrated a double dissociation where learning the task mainly via error-based mechanisms leads to cerebellar plasticity modifications but not long-term potentiation (LTP)-like plasticity changes in M1; while learning a similar action via reinforcement mechanisms elicited M1 LTP-like plasticity but not cerebellar plasticity changes. Our findings indicate that learning complex motor behavior is mediated by the interplay of different forms of learning, weighing distinct neural mechanisms in M1 and the cerebellum. Our study provides insights for designing effective interventions to enhance human motor learning. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  16. Qui s’assoit où ? Who sits down where? Strategies of seats’ occupation in the cinema

    Directory of Open Access Journals (Sweden)

    Claude Forest

    2012-04-01

    Full Text Available L’observation et l’analyse du comportement des spectateurs entrant dans une salle de cinéma, choisissant leurs places puis les libérant en fin de séance, ont permis de mettre en relief de nombreuses caractéristiques communes. Le choix et l’occupation d’un siège dans ces salles ne relève pas de la recherche d’un optimum technique de visionnement de la projection du film.  Une différenciation de certains comportements peut s’observer selon la composition du public qui varie elle-même selon la salle, le film ou  l’heure de séance, mais les interactions mimétiques entre spectateurs sont indéniables, et des mécanismes d’influence récurrents, indépendants de la composition du public, et peuvent être structurés par l’architecture et l’espace de la salle elle-même. L’essentiel des comportements de choix et libération des sièges obéissent avant tout à des règles et stratégies d’occupation d’un espace et d’un territoire, fortement conditionnées par l’âge et surtout le sexe du spectateur.The observation and the analysis of the spectators’ behavior entering a cinema, choosing their places then releasing them at the end of the meeting, made possible to highlight many common characteristics. The choice and the occupation of a seat don’t concern the search for a technical optimum of viewing of the film’s projection. A differentiation of certain behaviors can be observed according to the composition of the public which varies itself according to the room, film or the hour of meeting, but the interactions mimetic between spectators is undeniable, and the recurring mechanisms of influence, independent of public’s composition, and can be structured by the architecture and the space of the room itself. The main part of behaviors for the choice and the release of the seats first obey rules and strategies of occupation of a space and a territory, strongly conditioned by the age and especially the sex

  17. Fruit production in three masting tree species does not rely on stored carbon reserves.

    Science.gov (United States)

    Hoch, Günter; Siegwolf, Rolf T W; Keel, Sonja G; Körner, Christian; Han, Qingmin

    2013-03-01

    Fruiting is typically considered to massively burden the seasonal carbon budget of trees. The cost of reproduction has therefore been suggested as a proximate factor explaining observed mast-fruiting patterns. Here, we used a large-scale, continuous (13)C labeling of mature, deciduous trees in a temperate Swiss forest to investigate to what extent fruit formation in three species with masting reproduction behavior (Carpinus betulus, Fagus sylvatica, Quercus petraea) relies on the import of stored carbon reserves. Using a free-air CO2 enrichment system, we exposed trees to (13)C-depleted CO2 during 8 consecutive years. By the end of this experiment, carbon reserve pools had significantly lower δ(13)C values compared to control trees. δ(13)C analysis of new biomass during the first season after termination of the CO2 enrichment allowed us to distinguish the sources of built-in carbon (old carbon reserves vs. current assimilates). Flowers and expanding leaves carried a significant (13)C label from old carbon stores. In contrast, fruits and vegetative infructescence tissues were exclusively produced from current, unlabeled photoassimilates in all three species, including F. sylvatica, which had a strong masting season. Analyses of δ(13)C in purified starch from xylem of fruit-bearing shoots revealed a complete turn-over of starch during the season, likely due to its usage for bud break. This study is the first to directly demonstrate that fruiting is independent from old carbon reserves in masting trees, with significant implications for mechanistic models that explain mast seeding.

  18. High sugar-induced insulin resistance in Drosophila relies on the lipocalin Neural Lazarillo.

    Directory of Open Access Journals (Sweden)

    Matthieu Y Pasco

    Full Text Available In multicellular organisms, insulin/IGF signaling (IIS plays a central role in matching energy needs with uptake and storage, participating in functions as diverse as metabolic homeostasis, growth, reproduction and ageing. In mammals, this pleiotropy of action relies in part on a dichotomy of action of insulin, IGF-I and their respective membrane-bound receptors. In organisms with simpler IIS, this functional separation is questionable. In Drosophila IIS consists of several insulin-like peptides called Dilps, activating a unique membrane receptor and its downstream signaling cascade. During larval development, IIS is involved in metabolic homeostasis and growth. We have used feeding conditions (high sugar diet, HSD that induce an important change in metabolic homeostasis to monitor possible effects on growth. Unexpectedly we observed that HSD-fed animals exhibited severe growth inhibition as a consequence of peripheral Dilp resistance. Dilp-resistant animals present several metabolic disorders similar to those observed in type II diabetes (T2D patients. By exploring the molecular mechanisms involved in Drosophila Dilp resistance, we found a major role for the lipocalin Neural Lazarillo (NLaz, a target of JNK signaling. NLaz expression is strongly increased upon HSD and animals heterozygous for an NLaz null mutation are fully protected from HSD-induced Dilp resistance. NLaz is a secreted protein homologous to the Retinol-Binding Protein 4 involved in the onset of T2D in human and mice. These results indicate that insulin resistance shares common molecular mechanisms in flies and human and that Drosophila could emerge as a powerful genetic system to study some aspects of this complex syndrome.

  19. Experiencias de montaje creativo: de la historia oral a la imagen en movimiento ¿Quién escribe la historia oral?

    Directory of Open Access Journals (Sweden)

    Silvia Rivera Cusicanqui

    2012-11-01

    Full Text Available Este artículo marca la apertura de Silvia Rivera al mundo de la sociología de la imagen y del montaje audiovisual. De este modo nos ofrece una reflexión importante sobre la práctica de la historia oral ¿Quién escucha? ¿Quién habla? Por otro lado, nos invita a pensar acerca de la producción audiovisual y la autoría, vinculándola con los distintos movimientos sociales y políticos de gran influencia en la historia social boliviana, como el anarquismo, el katarismo y el indianismo. Finalmente nos comparte los procesos creativos que la llevaron a trabajar en el cine, mayoritariamente en el género de docu ficción.

  20. Alimentación de bovinos con ensilado de mezclas de banano de rechazo y ráquis en diferentes proporciones

    Directory of Open Access Journals (Sweden)

    J. C. De la Cruz-Hernández

    2006-01-01

    Full Text Available Con el propósito de evaluar el comportamiento productivo de bovinos consumiendo ensilado de mezclas de banano de rechazo como fruta y ráquis en diferentes proporciones, se realizó una prueba de alimentación con 12 bovinos cebú comercial, machos, enteros, con un peso promedio de 168±17 kg, a los que se les asignó, de manera aleatoria, cada uno de los siguientes tratamientos: I ensilado con 50% banano y 50% ráquis; II ensilado con 75% banano y 25% ráquis; y III un grupo testigo con zacate Taiwán (Pennisetum purpureum. Los animales recibieron, además, 1.1 kg de pasta de soya como fuente proteica y 50 g de una premezcla comercial de minerales y sal común. La prueba tuvo una duración de 120 días, más un tiempo de adaptación de 15, periodo en el que las dietas se ofrecieron a libertad. Los animales fueron pesados cada 30 días y se les llevó diariamente el control de consumo de alimento. Las mejores (P0.05 entre ellos. El consumo de alimento base húmeda (CABH no presentó diferencias significativas (P>0.05 entre tratamientos; sin embargo, el consumo de alimento base seca (CABS fue mayor (P<0.05 en el tratamiento ensilado de banano-ráquis 75:25 comparado con el de 50:50 (6.433 vs. 4.308 kg. El consumo de materia seca/100 kg de peso vivo fue mayor (P<0.05 para los animales que consumieron zacate Taiwán y ensilado de banano-ráquis 75:25 (2.334 y 1.990, comparados con los del ensilado 50:50 (1.413. El consumo de proteína cruda en kg fue mayor (P<0.05 para los animales alimentados con zacate Taiwán. Porcentualmente, el consumo de proteína cruda fue mayor (P<0.05 en los animales que consumieron zacate Taiwán y ensilado de banano-ráquis 50:50 (16.99 y 17.36 %. La mayor eficiencia alimenticia (P<0.05 la obtuvieron los animales que consumieron el ensilado de banano-ráquis 50:50. El análisis económico de este sistema de alimentación nos indica que se obtuvieron las mayores ganancias con el uso de los ensilados, siendo el mejor

  1. The Integration of Realistic Episodic Memories Relies on Different Working Memory Processes: Evidence from Virtual Navigation

    Directory of Open Access Journals (Sweden)

    Gaën Plancher

    2018-01-01

    central elements. By contrast, the prevention of visuo-spatial maintenance interfered both with the encoding of the temporal context and with the binding. These results suggest that the integration of realistic episodic memories relies on different working memory processes that depend on the nature of the traces.

  2. The Integration of Realistic Episodic Memories Relies on Different Working Memory Processes: Evidence from Virtual Navigation.

    Science.gov (United States)

    Plancher, Gaën; Gyselinck, Valérie; Piolino, Pascale

    2018-01-01

    contrast, the prevention of visuo-spatial maintenance interfered both with the encoding of the temporal context and with the binding. These results suggest that the integration of realistic episodic memories relies on different working memory processes that depend on the nature of the traces.

  3. Object Categorization in Finer Levels Relies More on Higher Spatial Frequencies and Takes Longer.

    Science.gov (United States)

    Ashtiani, Matin N; Kheradpisheh, Saeed R; Masquelier, Timothée; Ganjtabesh, Mohammad

    2017-01-01

    The human visual system contains a hierarchical sequence of modules that take part in visual perception at different levels of abstraction, i.e., superordinate, basic, and subordinate levels. One important question is to identify the "entry" level at which the visual representation is commenced in the process of object recognition. For a long time, it was believed that the basic level had a temporal advantage over two others. This claim has been challenged recently. Here we used a series of psychophysics experiments, based on a rapid presentation paradigm, as well as two computational models, with bandpass filtered images of five object classes to study the processing order of the categorization levels. In these experiments, we investigated the type of visual information required for categorizing objects in each level by varying the spatial frequency bands of the input image. The results of our psychophysics experiments and computational models are consistent. They indicate that the different spatial frequency information had different effects on object categorization in each level. In the absence of high frequency information, subordinate and basic level categorization are performed less accurately, while the superordinate level is performed well. This means that low frequency information is sufficient for superordinate level, but not for the basic and subordinate levels. These finer levels rely more on high frequency information, which appears to take longer to be processed, leading to longer reaction times. Finally, to avoid the ceiling effect, we evaluated the robustness of the results by adding different amounts of noise to the input images and repeating the experiments. As expected, the categorization accuracy decreased and the reaction time increased significantly, but the trends were the same. This shows that our results are not due to a ceiling effect. The compatibility between our psychophysical and computational results suggests that the temporal

  4. Energetic solutions of Rock Sandpipers to harsh winter conditions rely on prey quality

    Science.gov (United States)

    Ruthrauff, Daniel R.; Dekinga, Anne; Gill, Robert E.; Piersma, Theunis

    2018-01-01

    Rock Sandpipers Calidris ptilocnemis have the most northerly non-breeding distribution of any shorebird in the Pacific Basin (upper Cook Inlet, Alaska; 61°N, 151°W). In terms of freezing temperatures, persistent winds and pervasive ice, this site is the harshest used by shorebirds during winter. We integrated physiological, metabolic, behavioural and environmental aspects of the non-breeding ecology of Rock Sandpipers at the northern extent of their range to determine the relative importance of these factors in facilitating their unique non-breeding ecology. Not surprisingly, estimated daily energetic demands were greatest during January, the coldest period of winter. These estimates were greatest for foraging birds, and exceeded basal metabolic rates by a factor of 6.5, a scope of increase that approaches the maximum sustained rate of energetic output by shorebirds during periods of migration, but far exceeds these periods in duration. We assessed the quality of their primary prey, the bivalve Macoma balthica, to determine the daily foraging duration required by Rock Sandpipers to satisfy such energetic demands. Based on size-specific estimates of M. balthica quality, Rock Sandpipers require over 13 h/day of foraging time in upper Cook Inlet in January, even when feeding on the highest quality prey. This range approaches the average daily duration of mudflat availability in this region (c. 18 h), a maximum value that annually decreases due to the accumulation of shore-fast ice. Rock Sandpipers are likely to maximize access to foraging sites by following the exposure of ice-free mudflats across the upper Cook Inlet region and by selecting smaller, higher quality M. balthica to minimize foraging times. Ultimately, this unusual non-breeding ecology relies on the high quality of their prey resources. Compared with other sites across their range, M. balthica from upper Cook Inlet have relatively light shells, potentially the result of the region

  5. You can't rely on color, yet we all do 2.0 (Manuscript Only)

    Science.gov (United States)

    van Nes, Floris L.

    2014-01-01

    Everybody views and uses color from early childhood onwards. But this magnificent property of all objects around us turns out to be elusive if you try to specify it and communicate it to another person. Also, people often don't know what effects color may have under different conditions. However, color is so important and omnipresent, that people can hardly avoid to 'rely on it' - so they do, in particular on its predictability. Thus, there is a discrepancy between the seeming self-evidence of color and the difficulty in specifying it accurately, for the prevailing circumstances. In order to analyze this situation, and possibly remedy it, a short historic perspective of the utilization and specification of color is given. The 'utilization' includes the emotional effects of color, which are important in, for instance, interior decorating but also play a role in literature and religion. 'Specification' begins with the early efforts by scientists, philosophers and artists to bring some order and understanding in what was observed with and while using color. Color has a number of basic functions: embellishment; attracting attention; coding; and bringing order in text by causing text parts presented in the same color to be judged as belonging together. People with a profession that involves color choices for many others, such as designers and manufacturers of products, including electronic visual displays, should have a fairly thorough knowledge of colorimetry and color perception. Unfortunately, they often don't, simply because for 'practitioners' whose work involves different aspects, applying color being only one of those, the available tools for specifying and applying color turn out to be too difficult to use. Two consequences of an insufficient knowledge of the effects color may have are given here. The first of these consequences, on color blindness, relates to 8% of the population, but the second one, on reading colored text, bears on everyone. Practical

  6. Rôle de la société civile pour ce qui est d'influencer les politiques de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Rôle de la société civile pour ce qui est d'influencer les politiques de santé publique en faveur des femmes autochtones du Mexique. Au Mexique, les iniquités relatives à l'accès aux services de santé et aux services connexes sont sensiblement plus marquées chez les populations autochtones, et en particulier chez les ...

  7. The Prescription Pattern of Chinese Herbal Products That Contain Dang-Qui and Risk of Endometrial Cancer among Tamoxifen-Treated Female Breast Cancer Survivors in Taiwan: A Population-Based Study

    Science.gov (United States)

    Wu, Chien-Tung; Lai, Jung-Nien; Tsai, Yueh-Ting

    2014-01-01

    Purpose The increased practice of traditional Chinese medicine worldwide has raised concerns regarding herb-drug interactions. We analyzed the usage of Chinese herbal products containing dang-qui and investigated whether dang-qui therapy increases endometrial cancer risk among tamoxifen-treated breast cancer survivors in Taiwan. Methods All patients newly diagnosed with invasive breast cancer who received tamoxifen treatment from January 1, 1998, to December 31, 2008 were selected from the National Health Insurance Research Database. The usage, frequency of service and type of Chinese herbal products containing dang-qui prescribed across the 31,970 survivors were evaluated. Logistic regression method was employed to estimate the odds ratios for utilization of Chinese herbal products containing dang-qui. Cox proportional hazard regression was performed to calculate the hazard ratio of endometrial cancer associated with dang-qui use within the cohort. Results Almost one in two study subjects had used dang-qui. Among 31,938 tamoxifen-treated breast cancer survivors, 157 cases of subsequent endometrial cancer were identified. The hazard ratio for development of endometrial cancer among breast cancer survivors aged 20–79 years who had taken dang-qui after tamoxifen treatment was decreased compared to survivors who had never used dang-qui (HR: 0.61, 95%CI: 0.44–0.84). To minimise potential confounding factors, women with breast cancer in the reproductive age were excluded from further analysis, and the negative relationship between dang-qui consumption and subsequent endometrial cancer among breast cancer survivors aged 55–79 years was still observed, although not significantly (HR: 0.74, 95%CI: 0.46–1.17). Conclusions Dang-qui consumption is common among breast cancer survivors aged 20–79 years and seems decrease the risk of subsequent endometrial cancer after less than a cumulative dose of 7,500 mg of tamoxifen treatment. PMID:25485843

  8. Konfuciānisma, daoisma un budisma mantojums Ķīnas tautas reliģijā

    OpenAIRE

    Dudaļeva, Jūlija

    2014-01-01

    Šī bakalaura darba nosaukums ir „Konfuciānisma, daoisma un budisma mantojums Ķīnas tautas reliģijā”. Nosaukums ķīniešu tautas reliģijas ir pētnieku izveidots, un tas neatbilst nevienam tradicionālam ķīniešu nosaukumam. Tautas reliģija ir brīvi strukturēts ticību, prakses, dievību, mītu un vērtību savienojums, kas ietver sevī elementus no senču dievkalpojumiem, mirušo kulta, dabas pielūgsmes, animisma, vietējām tradīcijām, daoisma, konfuciānisma un budisma. Darba mērķis ir izpētīt konfuciān...

  9. Crystal-face growth rate: role of the neighbouring concentration; Vitesse de croissance d'une face cristalline: role de la concentration qui regne a son voisinage

    Energy Technology Data Exchange (ETDEWEB)

    Itti, R

    1967-07-01

    A study has been made of the phenomena occurring in the neighbourhood of a growing crystal-face, with the help of several methods based on interferometric observation. If the system is considered at a given moment, it is possible to express the growth rate of the crystal in two ways: 1) using the origin of the solute contributing to the growth, by application of Fick's law modified in certain cases by a correction factor involving the absolute value of the concentration near the crystal face. 2) directly, using the supersaturation in the crystal-face neighbourhood. On the other hand, if an attempt is made to take into account the changes in growth rate with time, it is seen that this rate is not dependent on diffusion phenomena, but that the convection currents in the solution play an important role. (author) [French] Les phenomenes qui ont lieu dans la solution au voisinage d'un cristal en voie de croissance ont ete etudies grace a plusieurs methodes d'observation interferometriques. Si l'on considere la preparation a un instant donne, il est possible d'exprimer la vitesse de croissance du cristal de deux manieres: 1) a partir de la provenance du solute necessaire a la croissance, par application de l'equation de Fick moyennant, dans certains cas, un facteur correctif faisant intervenir la valeur absolue de la concentration au voisinage de la face, 2) directement a partir de la sursaturation qui regne pres de la face. Par contre, si l'on essaie de rendre compte de l'evolution de la vitesse de croissance au cours du temps, on voit que celle-ci n'est pas commandee par les phenomenes de diffusion, mais que les courants de convection qui existent dons la solution jouent un role important. (auteur)

  10. Estudio Biomecanico de la Zancada. 7.52 Record de España de 60 MV de Jackson Quiñonez.

    OpenAIRE

    González Frutos, Pablo; Mallo Sainz, Javier; Veiga Fernandez, Santiago; Navarro Cabello, Enrique

    2009-01-01

    Los resultados que a continuación se presentan hacen referencia al Record de España de 60 metros vallas (en adelante, mv) conseguido por el atleta Jackson Quiñonez (JQ) en la final del 44º Campeonato de España de pista cubierta - Valencia 08. Estos datos forman parte de un estudio global de todas las series de 60 mv y 60 metros lisos (ml) durante el 44º Campeonato de España y el 12th IAAF World Indoor Championship Valencia 2008, en las cuales se aplica una nueva metodología para la obtención ...

  11. Factores predominantes que determinan el clima organizacional de la I.E. José Abelardo Quiñones del distrito de Mala-Cañete

    OpenAIRE

    Urbina Díaz, Lenny Esther

    2016-01-01

    La tesis tiene por objetivo identificar los factores que determinan el clima organizacional de la I.E. José Abelardo Quiñones de Mala, Cañete. Para ello, se ha estudiado el marco teórico sobre la variable de estudio: el clima organizacional. En la investigación se utilizó la metodología de tipo cuantitativo, basada en el paradigma positivista. Además se aplicó un cuestionario adaptado a la realidad del estudio. Las encuestas aplicadas al personal de la institución fueron analizadas mediante e...

  12. 16 CFR 1115.5 - Reporting of failures to comply with a voluntary consumer product safety standard relied upon by...

    Science.gov (United States)

    2010-01-01

    ... voluntary consumer product safety standard relied upon by the Commission under section 9 of the CPSA. 1115.5 Section 1115.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SUBSTANTIAL PRODUCT HAZARD REPORTS General Interpretation § 1115.5 Reporting of failures to comply...

  13. Caution required when relying on a colleague's advice; a comparison between professional advice and evidence from the literature

    NARCIS (Netherlands)

    Schaafsma, Frederieke; Verbeek, Jos; Hulshof, Carel; van Dijk, Frank

    2005-01-01

    Background: Occupational Physicians rely especially on advice from colleagues when answering their information demands. On the other hand, Evidence-based Medicine (EBM) promotes the use of up-to-date research literature instead of experts. To find out if there was a difference between expert-based

  14. 78 FR 29392 - Embedded Digital Devices in Safety-Related Systems, Systems Important to Safety, and Items Relied...

    Science.gov (United States)

    2013-05-20

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0098] Embedded Digital Devices in Safety-Related Systems, Systems Important to Safety, and Items Relied on for Safety AGENCY: Nuclear Regulatory Commission. ACTION... (NRC) is issuing for public comment Draft Regulatory Issue Summary (RIS) 2013-XX, ``Embedded Digital...

  15. Anemia predicts thromboembolic events, bleeding complications and mortality in patients with atrial fibrillation : insights from the RE-LY trial

    NARCIS (Netherlands)

    Westenbrink, B. D.; Alings, M.; Connolly, S. J.; Eikelboom, J.; Ezekowitz, M. D.; Oldgren, J.; Yang, S.; Pongue, J.; Yusuf, S.; Wallentin, L.; van Gilst, W. H.

    BackgroundAnemia may predispose to thromboembolic events or bleeding in anticoagulated patients with atrial fibrillation (AF). ObjectivesTo investigate whether anemia is associated with thromboembolic events and bleeding in patients with AF. Patients and methodsWe retrospectively analyzed the RE-LY

  16. Immobilization of α-Amylase from Anoxybacillus sp. SK3-4 on ReliZyme and Immobead Supports

    Directory of Open Access Journals (Sweden)

    Ummirul Mukminin Kahar

    2016-09-01

    Full Text Available α-Amylase from Anoxybacillus sp. SK3-4 (ASKA is a thermostable enzyme that produces a high level of maltose from starches. A truncated ASKA (TASKA variant with improved expression and purification efficiency was characterized in an earlier study. In this work, TASKA was purified and immobilized through covalent attachment on three epoxide (ReliZyme EP403/M, Immobead IB-150P, and Immobead IB-150A and an amino-epoxide (ReliZyme HFA403/M activated supports. Several parameters affecting immobilization were analyzed, including the pH, temperature, and quantity (mg of enzyme added per gram of support. The influence of the carrier surface properties, pore sizes, and lengths of spacer arms (functional groups on biocatalyst performances were studied. Free and immobilized TASKAs were stable at pH 6.0–9.0 and active at pH 8.0. The enzyme showed optimal activity and considerable stability at 60 °C. Immobilized TASKA retained 50% of its initial activity after 5–12 cycles of reuse. Upon degradation of starches and amylose, only immobilized TASKA on ReliZyme HFA403/M has comparable hydrolytic ability with the free enzyme. To the best of our knowledge, this is the first report of an immobilization study of an α-amylase from Anoxybacillus spp. and the first report of α-amylase immobilization using ReliZyme and Immobeads as supports.

  17. «Neutre est le seul genre qui me convienne»: retoriche dell’androginia nell’opera di Claude Cahun

    Directory of Open Access Journals (Sweden)

    Silvia Nugara

    2014-05-01

    Full Text Available The article deals with the rhetoric and discursive strategies through which surrealist artist and writer Clade Cahun elaborates forms of self-representations which, by subverting gender norms, reinvent non only femininity but humanity overall. The analysis will be carried out on the basis of Roland Barthes’ reflections on androgyny which he elaborated during his course on Neutre at the Collège de France. For Barthes, Neutre is a vector of symbolic change: « un mélange, un dosage, une dialectique, non de l’homme et de la femme (génitalité, mais du masculin et du féminin. Ou mieux encore: l’homme en qui il y a du féminin, la femme en qui il y a du masculin ». Neutre is whatever breaks the binary opposition between terms A and B by assuming the form of either “not A nor B”, or “A+B”. Neutre is therefore an attempt to elude the doxa and all immutable binary scheme of meaning through linguistic and rhetoric strategies such as epicene nouns and names, impersonals, a fluctuant use of gender forms, amphibology, irony, paradox, parallelism, antiphrasis.

  18. Dis-moi qui te cite et je saurai ce que tu vaux que mesure vraiment la bibliométrie ?

    CERN Document Server

    Pansu, Pascal; Beauvois, Jean-Léon

    2013-01-01

    Comme tous les travailleurs, les chercheurs ne peuvent échapper à l'évaluation. Celle-ci ne peut être conduite par eux-mêmes. De nombreuses questions se posent : qui doit les évaluer ? À quel rythme ? Et surtout, sur quelles bases ? Sur leur réputation, leurs interventions, leur implication dans la discipline, leur présence dans la littérature scientifique ? Mais alors quelle littérature ? Comment apprécier cette présence ? Par le nombre de textes publiés ? La diversité des revues ? Par l'écho qu'ont les textes dans la littérature ? La bibliométrie tend aujourd'hui à saturer l'évaluation. Elle est une réponse à quelques-unes de ces questions. Elle propose une forme d'évaluation comptable qu'on voudrait objective mais qui comporte de nombreuses limites et ambiguïtés. Ce livre présente quelques outils bibliométriques comme les fameux «facteur d'impact» et «h-index» et, à travers une analyse des pratiques mises en oeuvre, montre que l'objectivité n'est pas au rendez-vous et que...

  19. Quand les proverbes français explicitent l’humain par le biais pronominal (qui/on ou nominal (homme/femme

    Directory of Open Access Journals (Sweden)

    Mercedes Banegas Saorín

    2016-12-01

    Full Text Available Nous nous penchons ici sur les proverbes introduits par les pronoms et par des syntagmes nominaux pour déterminer dans quelle mesure la structure syntaxique joue sur la structure informative de ces énoncés qui acquièrent un sens conventionnel codé. Nous les rapprochons des énoncés génériques, sans perdre de vue les propriétés auxquelles satisfont la plupart des proverbes : généricité, schéma implicatif et montée hypo-hypéronymique. Comme la classe des proverbes n’est pas formellement homogène, nous aboutissons, d’une part, à l’établissement d’une sous-classe des proverbes dits pronominaux et, d’autre part, à une nouvelle typologie des proverbes, très proche de celle des phrases génériques qui fait consensus.

  20. Cœur elle y gît rouge (qui gît dans l’élégie ?

    Directory of Open Access Journals (Sweden)

    Benoît Conort

    2012-08-01

    Full Text Available Si le recueil Cœur élégie rouge de James Sacré fait bien apparaître l’ombre d’une femme aimée et perdue, ne voir dans cette élégie qu’une dimension autobiographique serait réducteur, et il faut peut-être y entendre aussi, selon une approche réflexive, le poème qui échoue à restituer le monde, le végétal, les visages. De la sorte, l’élégie serait aussi le deuil de ce rêve, avec le constat de l’incompatibilité du poème et du monde, pour peu que le sujet lyrique s’abandonne à un aveu naïf de son amour. Le poème doit donc se reconstruire comme espérance, projet incessamment relancé d’une écriture par quoi la vie continue. L’élégie ne se contente plus de chanter la perte ni de méditer sur l’inadéquation de la langue, elle tire sa force d’un espoir qui renaît toujours et dont témoigne la prégnance de la métaphore végétale.

  1. Invitro genotoxicity, assessment of cytotoxicity and of Rely X luting cement on human lymphocyte cells before and after irradiation

    International Nuclear Information System (INIS)

    Shetty, Shilpa S.; Hegde, Mithra N.; Shabin; Hegde, Nidarsh D.; Suchetha Kumari; Sanjeev, Ganesh

    2013-01-01

    In dentistry, a luting agent is a viscous material placed between tooth structure and a prosthesis that by polymerization firmly attach the prosthesis to the tooth structure. Luting agents contact a large area of dentin when used for crown cementation. There is little information on biocompatibility tests, especially on the effect of electron beam irradiation on cytotoxicity for luting resin cements. To determine the in vitro cytotoxicity and genotoxicity of Rely X luting cement on human lymphocyte cells before and after irradiation. Rely X luting cement was obtained commercially. Samples were prepared as per the ISO standard size of 25x2x2 mm using polytetrafluoroethylene teflon mould and divided into two groups - non irradiated and irradiated groups. The samples in irradiated category were exposed to 200 Gy of electron beam irradiation at Microtron Centre, Mangalore University, Mangalore, India. For hemolysis the samples were immersed in phosphate buffer saline and incubated at 370℃ for 24 hrs, 7 days and 14 days. 200 μl of 24 hr material extract was mixed with human peripheral blood lymphocyte tested for comet assay by single cell DNA comet assay. Hemolytic activity of non irradiated Rely X luting cement after 24 hrs, 7 days and 14 days was 54.78±1.48, 69.91±2.41 and 43.21±0.92 respectively whereas hemolytic activity of irradiated Rely X luting cement after 24 hrs, 7 days and 14 days was 91.8±8.29, 56.95±19.7 and 41.34±12.30. The irradiation of Rely X luting cement with 200 Gy dose of electron beam irradiation caused an increase in the frequency of DNA damage when compared to that of the non-irradiated group. Based on the experimental condition, it is concluded that incomplete polymerization of the dental luting cements has resulted in the elution of the resin components which are responsible for the cytotoxicity and genotoxicity of Rely X luting cement on human lymphocyte cells. (author)

  2. Rely-Guarantee Protocols

    Science.gov (United States)

    2014-05-01

    University Pittsburgh, PA 15213 1School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA. 2Faculdade de Ciências e Tecnologia ...additional examples that are not in the ECOOP paper. This work was partially supported by Fundação para a Ciência e Tecnologia (Portuguese Foundation

  3. Einfluss von Flüssigkeitskontamination auf die Verbundfestigkeit von Wurzelkanalsealern (Adseal und RelyX Unicem)

    OpenAIRE

    Höfer, Margarita

    2010-01-01

    Ziel dieser Arbeit war es, eine Aussage über die Verbundfestigkeit des epoxidharz-basierten Wurzelkanalsealers Adseal und des selbstadhäsiven methacrylatbasierten Befestigungszements RelyX Unicem zum Wurzelkanaldentin in Abhängigkeit vom Verbleib der Spülflüssigkeit im Wurzelkanal zu treffen. Die Kontamination des Wurzelkanals wurde mittels dreier verschiedener Spüllösungen durchgeführt. Zu diesem Zweck wurden Scherfestigkeitsmessungen sowie lichtmikroskopische Untersuchungen der Sealer-Sprea...

  4. Les Kurdes en Irak : une communauté linguistique qui protège son identité nationale

    OpenAIRE

    Hussein, Nigar Ali

    2015-01-01

    La communauté linguistique kurde en Irak, autonome depuis 1991, voit aujourd’hui une situation de plurilinguisme important due à l’existence d’un grand nombre de réfugiés (plus de deux millions). D’autre part, malgré le statut officiel de la langue kurde en Irak, les Kurdes dans ce pays n’ont pas encore réussi à unifier une langue standard kurde ayant une même utilisation dans les systèmes éducatifs et les médias kurdes. Les Kurdes d’Irak, pour qui leur langue est largement considérée comme l...

  5. Inventaire des cavités souterraines abandonnées et cartographie des dangers qui leur sont liés

    Directory of Open Access Journals (Sweden)

    Claire ARNAL

    1994-12-01

    Full Text Available Un inventaire national des cavités souterraines abandonnées, des accidents de sol qui leur sont imputables et de leurs conséquences dommageables a été réalisé à l’échelle de 1/1 000 000 en 1993 et 1994 par le BRGM pour le ministère de l’Environnement (Direction de la Prévention des Pollutions et des Risques. Il a conduit à élaborer des documents cartographiques de synthèse et à définir des niveaux de dangers dont la localisation permettra de lancer des études plus détaillées en vue d’assurer la sécurité des personnes et des biens

  6. Phonological memory in sign language relies on the visuomotor neural system outside the left hemisphere language network.

    Science.gov (United States)

    Kanazawa, Yuji; Nakamura, Kimihiro; Ishii, Toru; Aso, Toshihiko; Yamazaki, Hiroshi; Omori, Koichi

    2017-01-01

    Sign language is an essential medium for everyday social interaction for deaf people and plays a critical role in verbal learning. In particular, language development in those people should heavily rely on the verbal short-term memory (STM) via sign language. Most previous studies compared neural activations during signed language processing in deaf signers and those during spoken language processing in hearing speakers. For sign language users, it thus remains unclear how visuospatial inputs are converted into the verbal STM operating in the left-hemisphere language network. Using functional magnetic resonance imaging, the present study investigated neural activation while bilinguals of spoken and signed language were engaged in a sequence memory span task. On each trial, participants viewed a nonsense syllable sequence presented either as written letters or as fingerspelling (4-7 syllables in length) and then held the syllable sequence for 12 s. Behavioral analysis revealed that participants relied on phonological memory while holding verbal information regardless of the type of input modality. At the neural level, this maintenance stage broadly activated the left-hemisphere language network, including the inferior frontal gyrus, supplementary motor area, superior temporal gyrus and inferior parietal lobule, for both letter and fingerspelling conditions. Interestingly, while most participants reported that they relied on phonological memory during maintenance, direct comparisons between letters and fingers revealed strikingly different patterns of neural activation during the same period. Namely, the effortful maintenance of fingerspelling inputs relative to letter inputs activated the left superior parietal lobule and dorsal premotor area, i.e., brain regions known to play a role in visuomotor analysis of hand/arm movements. These findings suggest that the dorsal visuomotor neural system subserves verbal learning via sign language by relaying gestural inputs to

  7. L’urbanisme qui vient

    Directory of Open Access Journals (Sweden)

    Laurent Matthey

    2014-12-01

    Full Text Available Depuis moins d’une dizaine d’années, le double registre des valeurs et du récit de communication prend une importance croissante dans la conduite des projets urbains. C’est cette transformation de la production urbanistique, co-occurrente d’une transformation de la condition d’urbaniste, que discute cet article. Pour ce faire, il revient sur l’avènement d’un urbanisme de coordination consécutif à la généralisation de l’idéologie du projet urbain. Dans un deuxième temps, l’hypothèse d’une dématérialisation de l’urbanisme corrélatif à l’émergence d’un paradigme du mouvant est discutée. Enfin, l’émergence des valeurs et du récit dans la conduite de projet urbain, simultanément à un affaissement de la règle et de la regula, est envisagée du point de vue de la reconfiguration du champ de la pratique professionnelle qu’il occasionne. Mobilisant librement le matériau d’une recherche récente consacrée aux métiers du territoire, il montre que les transformations en cours ne s’effectuent pas sans accroc, contrairement à ce qu’en disent les apologistes du nouvel urbanisme.

  8. Bene qui latuit bene vixit

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Sten

    2016-01-01

    The contribution attempts to build up a strong, fact based argument against the idea that only states are relevant for the history of international law. Empires and companies have played a major part, but this is largely ignored by main stream conceptions of international law. The contribution al...... argues – perhaps to provoke the subject of our tribute – that the role of companies and empires have been much better understood by the conservative Edmund Burke than the by liberal J.S. Mill or the socialist Karl Marx....

  9. ¿Quién es el sujeto en la investigación educativa? / Who is the Subject in Educational Research?

    Directory of Open Access Journals (Sweden)

    Alicia Gurdián-Fernández

    2011-12-01

    Full Text Available En este artículo argumento, en primer lugar, que la identidad de quien investiga incide no solo en su forma de investigar, sino también en los procesos de formación de sus estudiantes y, por ende, en la formación de las futuras investigadoras y los futuros investigadores educativos. En segundo lugar, señalo que las instituciones educativas, así como sus docentes, juegan un rol central en la construcción de identidades. En tercer lugar, enfatizo que de esta responsabilidad no se eximen quienes se dedican a la investigación educativa, por lo que les invito a reflexionar sobre: ¿Cuáles son nuestras responsabilidades en el proceso de construcción de identidades? ¿Quién es el sujeto de la educación? ¿Quién es el sujeto de la investigación educativa y en ella?¿Cuán inclusivas son nuestras nociones de sujeto educativo y del sujeto empírico?Mediante el desarrollo y análisis de interrogantes sobre temas como: la relación sujeto-objeto; el sujeto en la investigación educativa; el aporte de la subjetividad; la contribución de la fenomenología; entre otros, argumento que: a la autobiografía intelectual es un instrumento de gran potencialidad para comprender el tono y la dirección de un proceso investigativo y b centrar la atención en las personas, en su historia, sus relaciones sociales y su ambiente, como sujetos actuantes y no solo como objetos de estudio es un movimiento epistémico, político y ético, puesto que reconoce la acción del sujeto en el mundo y sobre este. Por último, apelo a que las investigadoras y los investigadores cualitativos no solo deben comprender quiénes son, sino que también deben hacerlo explícito puesto que hay un condicionamiento ético que lo demanda. AbstractIn this paper I argue, first, that the identity of the researcher has an impact not only in the way she/he invThis article explains, in the first place, that the identity of the researcher not only influences his way to do research, but

  10. L’expérience d’une patiente qui reçoit des soins pour la démence

    Science.gov (United States)

    Frank, Christopher; Forbes, Rev Faye

    2017-01-01

    Résumé Objectif Permettre aux médecins de famille de comprendre « l’expérience vécue » de la démence de la bouche d’une personne atteinte de démence—Faye Forbes, ministre anglicane de 64 ans atteinte de la maladie d’Alzheimer, qui donne son point de vue sur comment vivre avec la démence—et utiliser cette information pour améliorer les soins et les résultats. Sources d’information Une recherche a été effectuée dans MEDLINE sur Ovid entre janvier 2005 et février 2015, à l’aide des mots-clés anglais suivants : dementia, caregiver, perspectives et quality of health care. Les articles qui s’adressaient aux médecins de famille ont été sélectionnés. Des revues pertinentes et des articles de recherche originaux ont été utilisés, le cas échéant, s’ils s’appliquaient aux personnes atteintes de démence et à leurs soignants. Message principal Plusieurs cadres de référence organisent les principales expériences décrites par les patients et leurs soignants. Nous avons utilisé une revue de la littérature qualitative pour fournir un cadre de référence résumant l’expérience de Faye, en fonction des thèmes suivants : tenter d’obtenir un diagnostic, accéder au soutien et aux services, besoins en matière d’information, prise en charge de la maladie, et communication et attitudes. Conclusion Les médecins doivent tenir compte de ces thèmes lorsqu’ils planifient la prise en charge des personnes atteintes de démence. Il importe de tenter de comprendre l’expérience et le point de vue des personnes atteintes de démence et de leurs soignants afin de pouvoir dispenser des soins optimaux. PMID:28115451

  11. Influence of Computerized Sounding Out on Spelling Performance for Children who do and not rely on AAC

    Science.gov (United States)

    McCarthy, Jillian H.; Hogan, Tiffany P.; Beukelman, David R.; Schwarz, Ilsa E.

    2015-01-01

    Purpose Spelling is an important skill for individuals who rely on augmentative alternative communication (AAC). The purpose of this study was to investigate how computerized sounding out influenced spelling accuracy of pseudo-words. Computerized sounding out was defined as a word elongated, thus providing an opportunity for a child to hear all the sounds in the word at a slower rate. Methods Seven children with cerebral palsy, four who use AAC and three who do not, participated in a single subject AB design. Results The results of the study indicated that the use of computerized sounding out increased the phonologic accuracy of the pseudo-words produced by participants. Conclusion The study provides preliminary evidence for the use of computerized sounding out during spelling tasks for children with cerebral palsy who do and do not use AAC. Future directions and clinical implications are discussed. PMID:24512195

  12. Humans rely on the same rules to assess emotional valence and intensity in conspecific and dog vocalizations.

    Science.gov (United States)

    Faragó, Tamás; Andics, Attila; Devecseri, Viktor; Kis, Anna; Gácsi, Márta; Miklósi, Adám

    2014-01-01

    Humans excel at assessing conspecific emotional valence and intensity, based solely on non-verbal vocal bursts that are also common in other mammals. It is not known, however, whether human listeners rely on similar acoustic cues to assess emotional content in conspecific and heterospecific vocalizations, and which acoustical parameters affect their performance. Here, for the first time, we directly compared the emotional valence and intensity perception of dog and human non-verbal vocalizations. We revealed similar relationships between acoustic features and emotional valence and intensity ratings of human and dog vocalizations: those with shorter call lengths were rated as more positive, whereas those with a higher pitch were rated as more intense. Our findings demonstrate that humans rate conspecific emotional vocalizations along basic acoustic rules, and that they apply similar rules when processing dog vocal expressions. This suggests that humans may utilize similar mental mechanisms for recognizing human and heterospecific vocal emotions.

  13. Can we rely on the antiretroviral treatment as the only means for human immunodeficiency virusprevention? A Public Health perspective.

    Science.gov (United States)

    Mozalevskis, Antons; Manzanares-Laya, Sandra; García de Olalla, Patricia; Moreno, Antonio; Jacques-Aviñó, Constanza; Caylà, Joan A

    2015-11-01

    The evidence that supports the preventive effect of combination antiretroviral treatment (cART) in HIV sexual transmission suggested the so-called 'treatment as prevention' (TAP) strategy as a promising tool for slowing down HIV transmission. As the messages and attitudes towards condom use in the context of TAP appear to be somehow confusing, the aim here is to assess whether relying on cART alone to prevent HIV transmission can currently be recommended from the Public Health perspective. A review is made of the literature on the effects of TAP strategy on HIV transmission and the epidemiology of other sexual transmitted infections (STIs) in the cART era, and recommendations from Public Health institutions on the TAP as of February 2014. The evolution of HIV and other STIs in Barcelona from 2007 to 2012 has also been analysed. Given that the widespread use of cART has coincided with an increasing incidence of HIV and other STIs, mainly amongst men who have sex with men, a combination and diversified prevention methods should always be considered and recommended in counselling. An informed decision on whether to stop using condoms should only be made by partners within stable couples, and after receiving all the up-to-date information regarding TAP. From the public health perspective, primary prevention should be a priority; therefore relying on cART alone is not a sufficient strategy to prevent new HIV and other STIs. Copyright © 2014 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  14. Les déterminants internes qui évaluent la performance des banques islamiques : cas de la zone de Moyen Orient et Afrique du Nord

    Directory of Open Access Journals (Sweden)

    Hayet Dami

    2017-09-01

    Full Text Available Le but de cette recherche est d’étudier les déterminants internes qui évaluent la performance des 22 banques islamiques cotées en Bourse et ils ont appliqué la même norme comptable internationale dans la zone de Moyen Orient et Afrique du Nord en utilisant une analyse des indicateurs financiers tels que la rentabilité, la liquidité, la solvabilité et le risque de crédit, l’adéquation du capital, l’efficacité opérationnelle et l’efficacité d’allocation des ressources. Nous avons utilisé un modèle MCO avec une régression linéaire multiple comprenant de la variable dépendante (ROA ou ROE et de nombreuses variables indépendantes selon les données du panel. Les résultats empiriques indiquent que la liquidité, l’adéquation du capital, l’efficacité opérationnelle et l’efficacité d’allocation des ressources sont des déterminants significatifs dans notre étude. Par contre, les indicateurs de risque du crédit et la solvabilité ne sont pas significatifs pour évaluer la performance des banques islamiques au Moyen Orient et Afrique du Nord. Notre résultat est robust.

  15. L'électronique pour les débutants qui sèchent les cours mais soudent sans se brûler les doigts

    CERN Document Server

    Mallard, Rémy

    2012-01-01

    Par où commencer pour débuter en électronique ? Vais-je m'égarer en explorant l'internet ? Il regorge de schémas, mais sont-ils fiables ? Me faut-il un livre avec des montages simples ou plutôt un livre sur les composants ? Après trente ans de pratique, l'auteur de ce livre, resté l'éternel débutant qui réalisait lui-même son premier montage dès l'âge de dix ans, partage ici sa soif toujours vive d'apprendre. Fin pédagogue, il guide les débutants et répond aux questions que trop de livres laissent en suspens : "Quel type de fer à souder acheter ?"... "Un multimètre à 5 € peut-il suffire ?"... "Un oscilloscope est-il indispensable ?"... "Peut-on installer son montage dans une boîte à cigares ?"... Rémy Mallard démystifie l'électronique en n'utilisant que ce qu'il vous faut de théorie pour aborder joyeusement la pratique sans risque de faire de grosses bêtises. Vous apprendrez à identifier les composants et leur rôle (résistances, condensateurs, bobines, diodes, transistors, rela...

  16. Social plasticity relies on different neuroplasticity mechanisms across the brain social decision-making network in zebrafish

    Directory of Open Access Journals (Sweden)

    Magda C Teles

    2016-02-01

    Full Text Available Social living animals need to adjust the expression of their behavior to their status within the group and to changes in social context and this ability (social plasticity has an impact on their Darwinian fitness. At the proximate level social plasticity must rely on neuroplasticity in the brain social decision-making network (SDMN that underlies the expression of social behavior, such that the same neural circuit may underlie the expression of different behaviors depending on social context. Here we tested this hypothesis in zebrafish by characterizing the gene expression response in the SDMN to changes in social status of a set of genes involved in different types of neural plasticity: bdnf, involved in changes in synaptic strength; npas4, involved in contextual learning and dependent establishment of GABAergic synapses; neuroligins (nlgn1 and nlgn2 as synaptogenesis markers; and genes involved in adult neurogenesis (wnt3 and neurod. Four social phenotypes were experimentally induced: Winners and Losers of a real-opponent interaction; Mirror-fighters, that fight their own image in a mirror and thus do not experience a change in social status despite the expression of aggressive behavior; and non-interacting fish, which were used as a reference group. Our results show that each social phenotype (i.e. Winners, Losers and Mirror-fighters present specific patterns of gene expression across the SDMN, and that different neuroplasticity genes are differentially expressed in different nodes of the network (e.g. BDNF in the dorsolateral telencephalon, which is a putative teleost homologue of the mammalian hippocampus. Winners expressed unique patterns of gene co-expression across the SDMN, whereas in Losers and Mirror-fighters the co-expression patterns were similar in the dorsal regions of the telencephalon and in the supracommissural nucleus of the ventral telencephalic area, but differents in the remaining regions of the ventral telencephalon. These

  17. Social Plasticity Relies on Different Neuroplasticity Mechanisms across the Brain Social Decision-Making Network in Zebrafish.

    Science.gov (United States)

    Teles, Magda C; Cardoso, Sara D; Oliveira, Rui F

    2016-01-01

    Social living animals need to adjust the expression of their behavior to their status within the group and to changes in social context and this ability (social plasticity) has an impact on their Darwinian fitness. At the proximate level social plasticity must rely on neuroplasticity in the brain social decision-making network (SDMN) that underlies the expression of social behavior, such that the same neural circuit may underlie the expression of different behaviors depending on social context. Here we tested this hypothesis in zebrafish by characterizing the gene expression response in the SDMN to changes in social status of a set of genes involved in different types of neural plasticity: bdnf, involved in changes in synaptic strength; npas4, involved in contextual learning and dependent establishment of GABAergic synapses; neuroligins (nlgn1 and nlgn2) as synaptogenesis markers; and genes involved in adult neurogenesis (wnt3 and neurod). Four social phenotypes were experimentally induced: Winners and Losers of a real-opponent interaction; Mirror-fighters, that fight their own image in a mirror and thus do not experience a change in social status despite the expression of aggressive behavior; and non-interacting fish, which were used as a reference group. Our results show that each social phenotype (i.e., Winners, Losers, and Mirror-fighters) present specific patterns of gene expression across the SDMN, and that different neuroplasticity genes are differentially expressed in different nodes of the network (e.g., BDNF in the dorsolateral telencephalon, which is a putative teleost homolog of the mammalian hippocampus). Winners expressed unique patterns of gene co-expression across the SDMN, whereas in Losers and Mirror-fighters the co-expression patterns were similar in the dorsal regions of the telencephalon and in the supracommissural nucleus of the ventral telencephalic area, but differents in the remaining regions of the ventral telencephalon. These results

  18. Social Plasticity Relies on Different Neuroplasticity Mechanisms across the Brain Social Decision-Making Network in Zebrafish

    Science.gov (United States)

    Teles, Magda C.; Cardoso, Sara D.; Oliveira, Rui F.

    2016-01-01

    Social living animals need to adjust the expression of their behavior to their status within the group and to changes in social context and this ability (social plasticity) has an impact on their Darwinian fitness. At the proximate level social plasticity must rely on neuroplasticity in the brain social decision-making network (SDMN) that underlies the expression of social behavior, such that the same neural circuit may underlie the expression of different behaviors depending on social context. Here we tested this hypothesis in zebrafish by characterizing the gene expression response in the SDMN to changes in social status of a set of genes involved in different types of neural plasticity: bdnf, involved in changes in synaptic strength; npas4, involved in contextual learning and dependent establishment of GABAergic synapses; neuroligins (nlgn1 and nlgn2) as synaptogenesis markers; and genes involved in adult neurogenesis (wnt3 and neurod). Four social phenotypes were experimentally induced: Winners and Losers of a real-opponent interaction; Mirror-fighters, that fight their own image in a mirror and thus do not experience a change in social status despite the expression of aggressive behavior; and non-interacting fish, which were used as a reference group. Our results show that each social phenotype (i.e., Winners, Losers, and Mirror-fighters) present specific patterns of gene expression across the SDMN, and that different neuroplasticity genes are differentially expressed in different nodes of the network (e.g., BDNF in the dorsolateral telencephalon, which is a putative teleost homolog of the mammalian hippocampus). Winners expressed unique patterns of gene co-expression across the SDMN, whereas in Losers and Mirror-fighters the co-expression patterns were similar in the dorsal regions of the telencephalon and in the supracommissural nucleus of the ventral telencephalic area, but differents in the remaining regions of the ventral telencephalon. These results

  19. Influence of computerized sounding out on spelling performance for children who do and do not rely on AAC.

    Science.gov (United States)

    McCarthy, Jillian H; Hogan, Tiffany P; Beukelman, David R; Schwarz, Ilsa E

    2015-05-01

    Spelling is an important skill for individuals who rely on augmentative and alternative communication (AAC). The purpose of this study was to investigate how computerized sounding out influenced spelling accuracy of pseudo-words. Computerized sounding out was defined as a word elongated, thus providing an opportunity for a child to hear all the sounds in the word at a slower rate. Seven children with cerebral palsy, four who use AAC and three who do not, participated in a single subject AB design. The results of the study indicated that the use of computerized sounding out increased the phonologic accuracy of the pseudo-words produced by participants. The study provides preliminary evidence for the use of computerized sounding out during spelling tasks for children with cerebral palsy who do and do not use AAC. Future directions and clinical implications are discussed. We investigated how computerized sounding out influenced spelling accuracy of pseudowords for children with complex communication needs who did and did not use augmentative and alternative communication (AAC). Results indicated that the use of computerized sounding out increased the phonologic accuracy of the pseudo-words by participants, suggesting that computerized sounding out might assist in more accurate spelling for children who use AAC. Future research is needed to determine how language and reading abilities influence the use of computerized sounding out with children who have a range of speech intelligibility abilities and do and do not use AAC.

  20. Catalytic ozonation not relying on hydroxyl radical oxidation: A selective and competitive reaction process related to metal-carboxylate complexes

    KAUST Repository

    Zhang, Tao

    2014-01-01

    Catalytic ozonation following non-hydroxyl radical pathway is an important technique not only to degrade refractory carboxylic-containing organic compounds/matter but also to avoid catalyst deactivation caused by metal-carboxylate complexation. It is unknown whether this process is effective for all carboxylates or selective to special molecule structures. In this work, the selectivity was confirmed using O3/(CuO/CeO2) and six distinct ozone-resistant probe carboxylates (i.e., acetate, citrate, malonate, oxalate, pyruvate and succinate). Among these probe compounds, pyruvate, oxalate, and citrate were readily degraded following the rate order of oxalate>citrate>pyruvate, while the degradation of acetate, malonate, and succinate was not promoted. The selectivity was independent on carboxylate group number of the probe compounds and solution pH. Competitive degradation was observed for carboxylate mixtures following the preference order of citrate, oxalate, and finally pyruvate. The competitive degradation was ascribed to competitive adsorption on the catalyst surface. It was revealed that the catalytically degradable compounds formed bidentate chelating or bridging complexes with surface copper sites of the catalyst, i.e., the active sites. The catalytically undegradable carboxylates formed monodentate complexes with surface copper sites or just electrostatically adsorbed on the catalyst surface. The selectivity, relying on the structure of surface metal-carboxylate complex, should be considered in the design of catalytic ozonation process. © 2013 Elsevier B.V.

  1. Spatial Reorganization of the Endoplasmic Reticulum during Mitosis Relies on Mitotic Kinase Cyclin A in the Early Drosophila Embryo

    Science.gov (United States)

    Bergman, Zane J.; Mclaurin, Justin D.; Eritano, Anthony S.; Johnson, Brittany M.; Sims, Amanda Q.; Riggs, Blake

    2015-01-01

    Mitotic cyclin-dependent kinase with their cyclin partners (cyclin:Cdks) are the master regulators of cell cycle progression responsible for regulating a host of activities during mitosis. Nuclear mitotic events, including chromosome condensation and segregation have been directly linked to Cdk activity. However, the regulation and timing of cytoplasmic mitotic events by cyclin:Cdks is poorly understood. In order to examine these mitotic cytoplasmic events, we looked at the dramatic changes in the endoplasmic reticulum (ER) during mitosis in the early Drosophila embryo. The dynamic changes of the ER can be arrested in an interphase state by inhibition of either DNA or protein synthesis. Here we show that this block can be alleviated by micro-injection of Cyclin A (CycA) in which defined mitotic ER clusters gathered at the spindle poles. Conversely, micro-injection of Cyclin B (CycB) did not affect spatial reorganization of the ER, suggesting CycA possesses the ability to initiate mitotic ER events in the cytoplasm. Additionally, RNAi-mediated simultaneous inhibition of all 3 mitotic cyclins (A, B and B3) blocked spatial reorganization of the ER. Our results suggest that mitotic ER reorganization events rely on CycA and that control and timing of nuclear and cytoplasmic events during mitosis may be defined by release of CycA from the nucleus as a consequence of breakdown of the nuclear envelope. PMID:25689737

  2. Sociological investigation Students of Universities' Social-Political Trust in Iran: relying on secondary analysis of some national surveys

    Directory of Open Access Journals (Sweden)

    Sayed Mahdi Etemadifard

    2013-12-01

    Full Text Available Social system based on mutual trust among members continues to exist. Social trust in modem era is more important than earlier periods. Subject of current report is focused on the trust of Iranian students in different aspects. Main question in this investigation is about social-political trust of these students (based on trust in Islamic Republic of Iran at the past and present. This matter explored by secondary analysis of data, Relying on secondary analysis of some national surveys. Based on data and consequences of other researches we are going to illustrate the objective aspects of student's trust in current decades. The main sources for data collection at this stage include: All the public surveys conducted in the past four decades, the general data about students and their related assays. Trust students were evaluated on the following dimensions: trust in trade unions and various groups, trust in the clergy, directors of public trust and confidence in judges. Furthermore, the level of political engagement and participation in elections, satisfaction with economic situation, political situation and level of satisfaction with confidence in radio and television news. Reduction of public trust leads to reduced maximum student trust especially in the social and political dimensions.

  3. The perception of (naked only) bodies and faceless heads relies on holistic processing: Evidence from the inversion effect.

    Science.gov (United States)

    Bonemei, Rob; Costantino, Andrea I; Battistel, Ilenia; Rivolta, Davide

    2018-05-01

    Faces and bodies are more difficult to perceive when presented inverted than when presented upright (i.e., stimulus inversion effect), an effect that has been attributed to the disruption of holistic processing. The features that can trigger holistic processing in faces and bodies, however, still remain elusive. In this study, using a sequential matching task, we tested whether stimulus inversion affects various categories of visual stimuli: faces, faceless heads, faceless heads in body context, headless bodies naked, whole bodies naked, headless bodies clothed, and whole bodies clothed. Both accuracy and inversion efficiency score results show inversion effects for all categories but for clothed bodies (with and without heads). In addition, the magnitude of the inversion effect for face, naked body, and faceless heads was similar. Our findings demonstrate that the perception of faces, faceless heads, and naked bodies relies on holistic processing. Clothed bodies (with and without heads), on the other side, may trigger clothes-sensitive rather than body-sensitive perceptual mechanisms. © 2017 The British Psychological Society.

  4. Does brain creatine content rely on exogenous creatine in healthy youth? A proof-of-principle study.

    Science.gov (United States)

    Merege-Filho, Carlos Alberto Abujabra; Otaduy, Maria Concepción Garcia; de Sá-Pinto, Ana Lúcia; de Oliveira, Maira Okada; de Souza Gonçalves, Lívia; Hayashi, Ana Paula Tanaka; Roschel, Hamilton; Pereira, Rosa Maria Rodrigues; Silva, Clovis Artur; Brucki, Sonia Maria Dozzi; da Costa Leite, Claudia; Gualano, Bruno

    2017-02-01

    It has been hypothesized that dietary creatine could influence cognitive performance by increasing brain creatine in developing individuals. This double-blind, randomized, placebo-controlled, proof-of-principle study aimed to investigate the effects of creatine supplementation on cognitive function and brain creatine content in healthy youth. The sample comprised 67 healthy participants aged 10 to 12 years. The participants were given creatine or placebo supplementation for 7 days. At baseline and after the intervention, participants undertook a battery of cognitive tests. In a random subsample of participants, brain creatine content was also assessed in the regions of left dorsolateral prefrontal cortex, left hippocampus, and occipital lobe by proton magnetic resonance spectroscopy (1H-MRS) technique. The scores obtained from verbal learning and executive functions tests did not significantly differ between groups at baseline or after the intervention (all p > 0.05). Creatine content was not significantly different between groups in left dorsolateral prefrontal cortex, left hippocampus, and occipital lobe (all p > 0.05). In conclusion, a 7-day creatine supplementation protocol did not elicit improvements in brain creatine content or cognitive performance in healthy youth, suggesting that this population mainly relies on brain creatine synthesis rather than exogenous creatine intake to maintain brain creatine homeostasis.

  5. Symmetric Encryption Relying on Chaotic Henon System for Secure Hardware-Friendly Wireless Communication of Implantable Medical Systems

    Directory of Open Access Journals (Sweden)

    Taha Belkhouja

    2018-05-01

    Full Text Available Healthcare remote devices are recognized as a promising technology for treating health related issues. Among them are the wireless Implantable Medical Devices (IMDs: These electronic devices are manufactured to treat, monitor, support or replace defected vital organs while being implanted in the human body. Thus, they play a critical role in healing and even saving lives. Current IMDs research trends concentrate on their medical reliability. However, deploying wireless technology in such applications without considering security measures may offer adversaries an easy way to compromise them. With the aim to secure these devices, we explore a new scheme that creates symmetric encryption keys to encrypt the wireless communication portion. We will rely on chaotic systems to obtain a synchronized Pseudo-Random key. The latter will be generated separately in the system in such a way that avoids a wireless key exchange, thus protecting patients from the key theft. Once the key is defined, a simple encryption system that we propose in this paper will be used. We analyze the performance of this system from a cryptographic point of view to ensure that it offers a better safety and protection for patients.

  6. Caution required when relying on a colleague's advice; a comparison between professional advice and evidence from the literature

    Directory of Open Access Journals (Sweden)

    Hulshof Carel

    2005-08-01

    Full Text Available Abstract Background Occupational Physicians rely especially on advice from colleagues when answering their information demands. On the other hand, Evidence-based Medicine (EBM promotes the use of up-to-date research literature instead of experts. To find out if there was a difference between expert-based practice and EBM we compared professional advice on occupational health topics with best evidence from the literature. Methods We asked 14 occupational physicians to consult their usual information sources on 12 pre-conceived occupational health problems. The problems were presented in the form of case vignettes which contained sufficient clinical information to be used by the occupational physicians for the consultation of their experts. We had searched the literature for the best available evidence on the 12 problems, which made it possible to answer the clinical questions with a clear yes or no. Results The cases could be used by the occupational physicians as arising from their own practice. All together the occupational physicians consulted 75 different experts. Almost half of the consulted experts were near colleagues, 10% were industrial hygienists, 8% medical specialists and the rest had a varied background. Fifty three percent (95% confidence interval 42% to 65% of all professional advice was not in line with the research literature. In 18 cases (24% professional advice explicitly referred to up-to-date research literature as their used source. These cases were substantially less incorrect (17% than advice that had not mentioned the literature as a source (65% (difference 48%, 95% Confidence Interval from 27% to 69%. Conclusion Advice that occupational physicians routinely get in their daily practice differs substantially from best evidence from the literature. Occupational physicians who ask professional advice should always ask about the evidence of this advice.

  7. Caution required when relying on a colleague's advice; a comparison between professional advice and evidence from the literature

    Science.gov (United States)

    Schaafsma, Frederieke; Verbeek, Jos; Hulshof, Carel; van Dijk, Frank

    2005-01-01

    Background Occupational Physicians rely especially on advice from colleagues when answering their information demands. On the other hand, Evidence-based Medicine (EBM) promotes the use of up-to-date research literature instead of experts. To find out if there was a difference between expert-based practice and EBM we compared professional advice on occupational health topics with best evidence from the literature. Methods We asked 14 occupational physicians to consult their usual information sources on 12 pre-conceived occupational health problems. The problems were presented in the form of case vignettes which contained sufficient clinical information to be used by the occupational physicians for the consultation of their experts. We had searched the literature for the best available evidence on the 12 problems, which made it possible to answer the clinical questions with a clear yes or no. Results The cases could be used by the occupational physicians as arising from their own practice. All together the occupational physicians consulted 75 different experts. Almost half of the consulted experts were near colleagues, 10% were industrial hygienists, 8% medical specialists and the rest had a varied background. Fifty three percent (95% confidence interval 42% to 65%) of all professional advice was not in line with the research literature. In 18 cases (24%) professional advice explicitly referred to up-to-date research literature as their used source. These cases were substantially less incorrect (17%) than advice that had not mentioned the literature as a source (65%) (difference 48%, 95% Confidence Interval from 27% to 69%). Conclusion Advice that occupational physicians routinely get in their daily practice differs substantially from best evidence from the literature. Occupational physicians who ask professional advice should always ask about the evidence of this advice. PMID:16131405

  8. Access to Grafts in a Liver Transplant Center: Does It Rely on the Severity of the Waiting List Population?

    Science.gov (United States)

    Daciuk, N I; Quiñonez, E G; Poupard, M; Vergara Sandoval, R M; Mattera, F J

    2018-03-01

    The number of transplants performed relies, partially, on recipients' variables on the waiting list. The goal of this study was to compare recipients from a high-volume liver center in Argentina with the rest of the country. This study was a retrospective analysis of liver transplant recipients nationally between January 2013 and April 2017. It involved extracting data from the open database CRESI-SINTRA (the Argentinian database of the National Procurement Organization, an equivalent to the United Network for Organ Sharing); expressing results by percentages, medians, and interquartile ranges (IQRs); and comparing the national population with the population transplanted at Hospital El Cruce (HEC). The Mann-Whitney U test was used for analysis. Nationally, 1434 liver transplants were performed. A total of 177 (12.34%) were emergency status; 811 (56.6%) were by the Model for End-Stage Liver Disease (MELD) (n = 759)/PELD (Pediatric End-Stage Liver Disease) (n = 52), with a median graft assignment position of 5 (IQR, 3-10) in 57.2 days (IQR, 11-217). Median MELD access was 29 points (IQR, 24-33). A total of 446 (31.1%) had MELD exceptions; 249 (55.8%) of these were due to Milan hepatocellular carcinoma. At the HEC, 167 liver transplantations were performed; 26 (15.6%) were emergency status and 97 (58.1%) by MELD (none PELD). Their median graft assignment position was 4 (IQR, 4-16) in 19.1 days (IQR, 4-90); median MELD access was 28 points (IQR, 24-31). Forty-five patients (26.9%) had MELD exceptions; 31 (68.9%) were due to hepatocellular carcinoma. Our center has a larger proportion of recipients transplanted by emergency status and MELD, similar MELD access, and less waiting list time, reflecting our wide policy of liver graft acceptance. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. An Overview of the Characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function

    Directory of Open Access Journals (Sweden)

    Abolfazl Akbari

    2016-10-01

    Full Text Available Vitamin C (L-ascorbic acid or ascorbate is a biomolecule that participates in many biochemical processes. It is an essential nutrient for humans, however, in some species such as rodents and guinea pigs is synthesized. It has a variety of functions in the body that we might venture to say make it a very important antioxidant nature and pro-oxidant. L-ascorbic acidic a reduced form of vitamin C and dehydroascorbic acid (DHA is the oxidized form of ascorbate, both L-ascorbic acid and dihydroascorbic acid retain the vitamin C activity. Dehydro-ascorbate is reconverted to ascorbate in the cytosol by cytochrome b reductase and thioredoxin reductase in reactions involving NADH and NADPH, respectively. Ascorbate is transported into the cell via the sodium-dependent vitamin C transporters (SVCTs, which causes accumulation of ascorbate within cells against a concentration gradient. Dehydroascorbic acid, the oxidized form of ascorbate, is transported via glucose transporters family (GLUTs. The highest concentrations of ascorbate in the body are found in brain and adrenal gland. Vitamin C also acts as a co-factor in several enzyme reactions. This vitamin is an essential biochemical factor in the reproductive process. The pharmacophore of vitamin C is the ascorbate, ascorbate is an antioxidant.Ascorbate is a neuromodulator of glutamatergic and dopaminergic system and related behaviors. It also improves components of the immune system. Given the wide role of ascorbate, further investigation is necessary to evaluate the exact mechanism(s underlying these effects. In this review we will consider a short overview of the characteristics and function of vitamin C (relying on antioxidant function in various tissues.

  10. Reliģijas, apmierinātības ar dzīvi un pašvērtējuma saistība.

    OpenAIRE

    Bērziņa, Annija

    2015-01-01

    Šī darba mērķis ir noskaidrot saistību starp reliģiju, apmierinātību ar dzīvi un pašvērtējumu. Apmierinātība ar dzīvi sevī ietver laimi, subjektīvo labklājību un pozitīvas emocijas. Šī darba ietvaros vairāk tiks apskatīta subjektīvā labklājība. Reliģija ir ticība kam mistiskam , kas sevī ietver reliģisku normu ievērošanu, rituālus, ticību un būšanu reliģiskā kopienā. Starp subjektīvo labklājību un reliģiju pastāv pozitīva korelācija. Pašvērtējums ir cilvēka subjektīvs viedoklis par...

  11. 12 CFR 714.5 - What is required if you rely on an estimated residual value greater than 25% of the original cost...

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false What is required if you rely on an estimated residual value greater than 25% of the original cost of the leased property? 714.5 Section 714.5 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS LEASING § 714.5 What is...

  12. Research Advances: Pacific Northwest National Laboratory Finds New Way to Detect Destructive Enzyme Activity--Hair Dye Relies on Nanotechnology--Ways to Increase Shelf Life of Milk

    Science.gov (United States)

    King, Angela G.

    2007-01-01

    Recent advances in various research fields are described. Scientists at the Pacific Northwest National Laboratory have found a new way to detect destructive enzyme activity, scientists in France have found that an ancient hair dye used by ancient people in Greece and Rome relied on nanotechnology and in the U.S. scientists are developing new…

  13. [Zeme, vara un reliģija viduslaikos un jaunajas laikos Baltijas jūras reģionā] / Marija Golubeva

    Index Scriptorium Estoniae

    Golubeva, Marija, 1973-

    2011-01-01

    Arvustus: Zeme, vara un reliģija viduslaikos un jaunajas laikos Baltijas jūras reģionā / Hrsg. von Andris Šnē. Acta Universitatis Latviensis ; 725. (Riga: Verlag Latvijas Universitātes Akadēmiskais apgāds, 2009)

  14. Biological adhesion of the flatworm Macrostomum lignano relies on a duo-gland system and is mediated by a cell type-specific intermediate filament protein

    NARCIS (Netherlands)

    Lengerer, Birgit; Pjeta, Robert; Wunderer, Julia; Rodrigues, Marcelo; Arbore, Roberto; Schaerer, Lukas; Berezikov, Eugene; Hess, Michael W.; Pfaller, Kristian; Egger, Bernhard; Obwegeser, Sabrina; Salvenmoser, Willi; Ladurner, Peter

    2014-01-01

    Background: Free-living flatworms, in both marine and freshwater environments, are able to adhere to and release from a substrate several times within a second. This reversible adhesion relies on adhesive organs comprised of three cell types: an adhesive gland cell, a releasing gland cell, and an

  15. Lying relies on the truth

    NARCIS (Netherlands)

    Debey, E.; De Houwer, J.; Verschuere, B.

    2014-01-01

    Cognitive models of deception focus on the conflict-inducing nature of the truth activation during lying. Here we tested the counterintuitive hypothesis that the truth can also serve a functional role in the act of lying. More specifically, we examined whether the construction of a lie can involve a

  16. Restauración ecológica y paisajística del Arroyo de los Quiñones. San Sebastián de los Reyes, Madrid

    Directory of Open Access Journals (Sweden)

    Peinado Albendea, Pedro

    1996-04-01

    Full Text Available The restoration of the Arroyo (stream de los Quiñones (San Sebastián de los Reyes poses a problem whose solution consists in neutralizing the principal sources of its degradation. These sources are: waste water discharges, an urban solid waste dump, situated in the very bed of the stream, and the intensive aggregate extraction which made the stream itself disappear at various points. This article also deals with the recuperation of the surrounding wood in a natural and landscape-friendly way, which would facilitate the access and the walk along the sides of the stream. This would lead to the clearing of other areas of a high ecological value within this municipality.

    La restauración del Arroyo de los Quiñones (San Sebastián de los Reyes, Madrid plantea como problema resolver sus principales fuentes de degradación. Estas son los vertidos de aguas residuales, un vertedero de residuos sólidos urbanos ubicado en el cauce, y la intensiva extracción de áridos que ha llegado a hacer desaparecer el arroyo en diversas zonas. Posteriormente se plantea la recuperación del bosque ripario de una forma lo más natural paisajísticamente, facilitando el acceso y el paseo para des congestionar otras zonas de alto valor ecológico del término municipal.

  17. Le comte qui était comtesse : un cas de gynandrie au tribunal de Vienne (1890 The Count who was a Countess: a Case of Gynandry in the Court of Vienna (1890

    Directory of Open Access Journals (Sweden)

    Patrick Pognant

    2011-03-01

    Full Text Available Il s’agit d’une des premières expertises auprès des tribunaux de la Cour impériale conduite par Krafft-Ebing alors qu’il venait d’être nommé professeur de psychiatrie à Vienne. Il eut à mener cette expertise dans une affaire de mœurs à propos d’une jeune comtesse hongroise qui, selon lui, souffrait de gynandrie, ce qui l’aurait conduite à convoler en noces illégitimes avec une jeune fille en escroquant au passage son « beau-père ». Il sera notamment intéressant de voir comment Krafft-Ebing a orienté son expertise pour la faire coïncider avec la théorie qu’il avait élaborée à propos des psychopathies sexuelles (et notamment les degrés de l’homosexualité et comment il obtint l’acquittement de la jeune femme qui, d’ailleurs, passa le reste de sa vie dans la peau (et le pantalon d’un homme en se faisant appeler M. le Comte…This article is about one of the first expert testimonies presented to the tribunals of the imperial Court, conducted by Krafft-Ebing when he had just been named professor of psychiatry at Vienna. He was called in on a case involving a young Hungarian countess – in his view, suffering from gynandrism – charged with illegitimate marriage to a young woman and knowingly misrepresenting herself to her “father-in-law” in the process.  Of particular interest is the way Krafft-Ebing oriented his testimony, aligning it with the theory he had previously elaborated regarding sexual psychopathies (notably degrees of homosexuality. Of interest, too, is his role in the acquittal of the countess, who spent the rest of her life as a man (in body and dress, identifying himself as Monsieur le Comte…

  18. Quels types de fraudes rencontrent les institutions financières qui travaillent avec des lettres de crédits, comment sont-elles traitées et quelles pourraient être les solutions pour les éliminer ?

    OpenAIRE

    Ferreira Pinheiro, Fabio; Fragnière, Emmanuel

    2013-01-01

    Le but de ce travail est d’identifier les principaux problèmes qu’il existe dans le marché des Crédits documentaires et de trouver les améliorations qui peuvent être apportées sur le plan opérationnel, pour les banques, et sur les aspects légaux en général. Une des principales difficultés empêchant la Lettre de crédit d’être un moyen de paiement davantage sûr est la détection de faux documents, surtout pour les banques car elles sont responsables de les contrôler. De plus, certains clients ne...

  19. Femme, genre et politique en Grèce archaïque et classique. Autour d’Artémise d’Halicarnasse, l’amazone qui a existé

    Directory of Open Access Journals (Sweden)

    Violaine Sébillotte Cuchet

    2010-01-01

    Full Text Available Le dossier regroupe divers travaux rédigés sur la thématique des rapports individu/cité déclinée sur l’axe de l’intégration dans une filiation politique naturalisante (notion de patris et dans une catégorie de sexe (homme/femme. Le manuscrit sur Artémise est un travail d’histoire sociale du culturel dans une démarche critique de genre. Hérodote raconte l’histoire de cette reine d’Halicarnasse en Carie qui, à la tête d’une flottille, tient tête aux Athéniens lors de la bataille de Salamine (...

  20. Territorialisation à distance par caméra vidéo : Perception de la vidéosurveillance au quartier des Pâquis à Genève

    Directory of Open Access Journals (Sweden)

    F. Klauser

    2017-07-01

    Full Text Available Drawing upon two public opinion surveys conducted in Geneva in 2015 and 2016, the paper explores how video surveillance was lived and perceived by the residents of the monitored Pâquis area, as well as by the population at large. This study shows that the delegation of control to systems and individuals that are both spatially and socially detached from the monitored areas also results in a kind of `mental distance' that characterizes the relation between the monitored individuals and the system: People quickly forget about the cameras and withdraw from any conscious attempt to imagine what might be going on behind their back. The system thus gradually loses its relevance in people's everyday life. This, in turn, limits the symbolic power of the cameras to enduringly revitalize, and thus to properly re-territorialize, the monitored areas.

  1. Quelques remarques sur le projet d’une Histoire sociale des langues de France et les problèmes qui se sont posés lors de son élaboration

    Directory of Open Access Journals (Sweden)

    Kremnitz Georg

    2012-07-01

    Full Text Available Les conditions de la genèse du projet – les voies nouvelles que la liste Cerquiglini a ouvertes pour la sociolinguistique – et le collectif de chercheurs qui s’en occupe. Les motivations du collectif : rééquilibrer les relations entre production et réception linguistiques, donc un problème de la pratique de la recherche depuis la linguistique et comparative ; dénationaliser les histoires de la communication, donc rediscuter les idéologies implicites de la recherche ; repenser les différences entre histoire de la langue et grammaire historique. Les choix que le collectif a effectués : il a fallu privilégier les périodes moderne et contemporaine sans négliger les antécédents. Tout en partant de la liste Cerquiglini il a fallu la dépasser à certains points. Il était surtout important d’intégrer dans cette présentation également des langues qui ne figurent pas dans la liste tout en ayant joué un rôle considérable dans le passé, parfois en ce moment. Le but de l’effort est une présentation générale de l’histoire de la communication en France. Ceci permet également de prévoir certaines évolutions de la communication, en France comme ailleurs.

  2. Cytotoxicity Comparison of Harvard Zinc Phosphate Cement Versus Panavia F2 and Rely X Plus Resin Cements on Rat L929-fibroblasts.

    Science.gov (United States)

    Mahasti, Sahabi; Sattari, Mandana; Romoozi, Elham; Akbar-Zadeh Baghban, Alireza

    2011-01-01

    Resin cements, regardless of their biocompatibility, have been widely used in restorative dentistry during the recent years. These cements contain hydroxy ethyl methacrylate (HEMA) molecules which are claimed to penetrate into dentinal tubules and may affect dental pulp. Since tooth preparation for metal ceramic restorations involves a large surface of the tooth, cytotoxicity of these cements would be more important in fixed prosthodontic treatments. The purpose of this study was to compare the cytotoxicity of two resin cements (Panavia F2 and Rely X Plus) versus zinc phosphate cement (Harvard) using rat L929-fibroblasts in vitro. In this experimental study, ninety hollow glass cylinders (internal diameter 5-mm, height 2-mm) were made and divided into three groups. Each group was filled with one of three experimental cements; Harvard Zinc Phosphate cement, Panavia F2 resin cement and Rely X Plus resin cement. L929- Fibroblast were passaged and subsequently cultured in 6-well plates of 5×10(5) cells each. The culture medium was RPMI_ 1640. All samples were incubated in CO2. Using enzyme-linked immune-sorbent assay (ELISA) and (3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) (MTT) assay, the cytotoxicity of the cements was investigated at 1 hour, 24 hours and one week post exposure. Statistical analyses were performed via two-way ANOVA and honestly significant difference (HSD) Tukey tests. This study revealed significant differences between the three cements at the different time intervals. Harvard cement displayed the greatest cytotoxicity at all three intervals. After 1 hour Panavia F2 showed the next greatest cytotoxicity, but after 24-hours and oneweek intervals Rely X Plus showed the next greatest cytotoxicity. The results further showed that cytotoxicity decreased significantly in the Panavia F2 group with time (pHarvard cement group failed to showed no noticeable change in cytotoxicity with time. Although this study has limitations, it provides

  3. The description-experience gap and its relation to instructional control: Do people rely more on their experience than in objective descriptions?

    Directory of Open Access Journals (Sweden)

    Álvaro Viúdez

    2017-11-01

    Full Text Available The present work aims to reveal contradictory results obtained on two different fields; particularly from two studies conducted on the description-experience gap field showing that descriptions are neglected when personal experience is available (1,2, and several others conducted on the instructional control field getting to the opposite conclusion (3–8. To account for this contradiction, we hypothesized that participants from the studies of Jessup, Bishara and Busemeyer (1 and Lejarraga and Gonzalez (2 relied on their experience rather than on the descriptions because of the difficult, demanding nature of the probabilistic descriptions they faced. Enriched descriptions were created in our experiment to assess the contribution of this factor to the differential influence of the descriptions in choice behavior. Nonetheless, our hypothesis did not find support in the results and further research is needed to account for the aforementioned contradiction.

  4. Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure.

    Science.gov (United States)

    Kabisch, Maria; Hamann, Ute; Lorenzo Bermejo, Justo

    2017-10-17

    Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors. To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemented with the analysis of real data. Genotype concordance rates were used to compare the accuracies of coalescent-based and standard (IMPUTE2) imputation. Simulations revealed that, in LD-blocks, imputation accuracy relying on the basic coalescent was higher and less variable than with IMPUTE2. Explicit consideration of population growth and structure, even if present, did not practically improve accuracy. The advantage of coalescent-based over standard imputation increased with the minor allele frequency and it decreased with population stratification. Results based on real data indicated that, even in low-recombination regions, further research is needed to incorporate recombination in coalescence inference, in particular for studies with genetically diverse and admixed individuals. To exploit the full potential of coalescent-based methods for the imputation of missing genotypes in genetic studies, further methodological research is needed to reduce computer time, to take into account recombination, and to implement these methods in user-friendly computer programs. Here we provide reproducible code which takes advantage of publicly available software to facilitate

  5. QUI CONSTRUEIX EL NOSTRE IMAGINARI URBÀ?

    Directory of Open Access Journals (Sweden)

    Rodolfo Mejías Cubero

    2013-12-01

    Com a producte d’això es proposa la utilització d’un model d’anàlisi de la imatge urbana basat en variables extretes del context urbà local i des del punt de vista del vianant. Es planteja especialment una visió de la imatge a partir de com ens movem dins l’espai, de com estan construïdes visualment les seves relacions formals i les vivències que la caracteritzen.

  6. An inconvenient truth; Une verite qui derange

    Energy Technology Data Exchange (ETDEWEB)

    Al, Gore

    2007-01-15

    Our climate crisis may at times appear to be happening slowly, but in fact it is happening very quickly-and has become a true planetary emergency. The Chinese expression for crisis consists of two characters. The first is a symbol for danger; the second is a symbol for opportunity. In order to face down the danger that is stalking us and move through it, we first have to recognize that we are facing a crisis. So why is it that our leaders seem not to hear such clarion warnings? Are they resisting the truth because they know that the moment they acknowledge it, they will face a moral imperative to act? Is it simply more convenient to ignore the warnings? Perhaps, but inconvenient truths do not go away just because they are not seen. Indeed, when they are responded to, their significance does not diminish; it grows. (author)

  7. Neutrino, la petite particule qui monte

    CERN Multimedia

    Bonneau, Cécile

    2006-01-01

    IN 1956, a very discrete particle was detected for the first time. 50 years latter, the neutrino became a true star for physics. In the whole world, resarchers display detectors always more fantastic to catch it, or even use it. Full lights on seven experiments which promise to bring to light finally the most mysterious particle of modern science (8 pages)

  8. Qui est pauvre en Republique tcheque?

    Czech Academy of Sciences Publication Activity Database

    Večerník, Jiří

    2005-01-01

    Roč. 41, č. 1051 (2005), s. 30-41 ISSN 0590-0239 R&D Projects: GA AV ČR IBS7028351 Institutional research plan: CEZ:AV0Z70280505 Keywords : poverty * social policy * employment policy Subject RIV: AO - Sociology, Demography

  9. Erri de Luca: non ora, non qui

    Directory of Open Access Journals (Sweden)

    Mariarosaria Fabris

    1994-12-01

    Full Text Available The essential theme of Erri de Luca´s first novel is the conquest of word as a mean of communication with other people and, mainly, as a mean to make memory revive and to express one´s own feelings.

  10. Quis custodiet quem? (Who is in charge)

    International Nuclear Information System (INIS)

    Senders, J.W.

    1990-01-01

    The introduction of Artificial Intelligence into Nuclear Power Plant control rooms may have some unexpected and undersired psychological effects on the control room operators of the plant. These will arise from problems of 'interpersonal' relationships between Artificial Intelligences (AI) and Natural Intelligences (NI). Some of them will stem especially from a perception of loss of control over the work and the working environment. The discuss why perceptions of loss of control might arise, what some of the effects might be, and propose some ways of preventing their occurrence or overcoming their effects

  11. Maledetti Toscani de Curzio Malaparte ou d’un voyage au « pays » de ceux qui « cultivent l'herbe du ridicule » et la « mangent en salade »1

    OpenAIRE

    Rubat du Mérac, Marie-Anne

    2009-01-01

    Marie-Anne Rubat du Mérac se penche sur Maledetti toscani, où Malaparte décrit sa région natale et « ceux qui cultivent l’herbe du ridicule et la mangent en salade » : un livre impertinent qui joue avec la structure du récit de voyage, dans lequel les toscans, toujours prêts à rire, sont eux-mêmes vus par le regard ironique de l’auteur. Mais dans ces pages à la prose minutieusement travaillée, qui sont en fait un bel exercice de style où s’égrènent divers procédés du comique, il exerce aussi ...

  12. Insulte, disqualification, persuasion et tropes communicationnels : à qui l’insulte profite-t-elle ? Insult, Disqualification, Persuasion and “Communicational Trope”: Who would benefit from insults?

    Directory of Open Access Journals (Sweden)

    Geneviève Bernard Barbeau

    2012-04-01

    Full Text Available Partant d’une acception très large de l’argumentation, nous nous intéressons ici au lien entre insulte et persuasion afin de repenser la relation persuadeur / persuadé sous l’éclairage de celle d’insulteur / insulté. Cette conception fondamentalement interactionniste place au centre de l’analyse l’objet de persuasion et la (possibilité de satisfaction de l’acte, ainsi que toute la mise en scène, le décor et le public qui assiste à la représentation (pour reprendre la métaphore théâtrale de Goffman, sans négliger la dimension émotive de l’insulte. Insistant sur la dimension argumentative de l’insulte, nous tentons de montrer, à partir d’extraits de sites Internet d’évaluation de professionnels, que toute disqualification devant un tiers a comme visée de le persuader d’adhérer à la thèse implicite de la validité de la qualification péjorative, ce qui se manifeste, sur le plan perlocutoire, de deux manières : persuader de haïr (faire adhérer à la disqualification d’autrui et persuader d’agir (faire poser une action conséquente avec l’adhésion à la disqualification d’autrui.Starting from a very broad definition of argumentation, we are interested in the link between insult and persuasion, in order to rethink the persuader / persuaded relationship, under the light of the insulter / insulted relationship. This fundamentally interactionist concept analyses first and foremost the object of persuasion, and the (possibility of achievement of the action, as well as the staging, the set and the attending audience (to use again Goffman’s theatrical metaphor, without neglecting the emotional dimension, inherent to insult. We will attempt to demonstrate, based on excerpts taken from websites that enable users to post reviews of professionals, that any disqualification in the presence of third parties aims at persuading them to adhere to the implicit thesis supporting the validity of the

  13. Automatic and Intentional Number Processing Both Rely on Intact Right Parietal Cortex: A Combined fMRI and Neuronavigated TMS Study

    Science.gov (United States)

    Cohen Kadosh, Roi; Bien, Nina; Sack, Alexander T.

    2012-01-01

    Practice and training usually lead to performance increase in a given task. In addition, a shift from intentional toward more automatic processing mechanisms is often observed. It is currently debated whether automatic and intentional processing is subserved by the same or by different mechanism(s), and whether the same or different regions in the brain are recruited. Previous correlational evidence provided by behavioral, neuroimaging, modeling, and neuropsychological studies addressing this question yielded conflicting results. Here we used transcranial magnetic stimulation (TMS) to compare the causal influence of disrupting either left or right parietal cortex during automatic and intentional numerical processing, as reflected by the size congruity effect and the numerical distance effect, respectively. We found a functional hemispheric asymmetry within parietal cortex with only the TMS-induced right parietal disruption impairing both automatic and intentional numerical processing. In contrast, disrupting the left parietal lobe with TMS, or applying sham stimulation, did not affect performance during automatic or intentional numerical processing. The current results provide causal evidence for the functional relevance of right, but not left, parietal cortex for intentional, and automatic numerical processing, implying that at least within the parietal cortices, automatic, and intentional numerical processing rely on the same underlying hemispheric lateralization. PMID:22347175

  14. Trabajo no remunerado y reproductivo. ¿Quién debe de pagar la reproducción de la fuerza de trabajo de una nación?

    Directory of Open Access Journals (Sweden)

    Alicia Girón

    2016-01-01

    Full Text Available Se aborda el problema de ¿Quién debe de pagar el costo de la reproducción de la fuerza del trabajo de una nación? en relación a la ampliación de la participación de las mujeres en el mercado laboral y el desdibujamiento del Estado del Bienestar, de la cual surge la preocupación sobre el trabajo desempeñado por las mujeres en la unidad familiar. Además examina la búsqueda por contabilizar el trabajo no remunerado. A lo largo de las últimas cuatro décadas las crisis recurrentes han sido la consecución de frecuentes planes de estabilización, reestructuración y renegociaciones de los créditos con acreedores e inversionistas financieros institucionales en los mercados financieros. La orientación del gasto público al pago del servicio de la deuda y a los compromisos de los países con el exterior han ido mermando la capacidad del gasto público principalmente en cuanto al gasto social como el gasto en educación y el gasto en salud. Lo ha impactado en las políticas públicas. Un agradecimiento a Andrea Reyes, becaria del Consejo Nacional de Ciencias y Tecnología (CONACYT, por la recopilación del material para este trabajo.

  15. How and When Do Insects Rely on Endogenous Protein and Lipid Resources during Lethal Bouts of Starvation? A New Application for 13C-Breath testing.

    Science.gov (United States)

    McCue, Marshall D; Guzman, R Marena; Passement, Celeste A; Davidowitz, Goggy

    2015-01-01

    Most of our understanding about the physiology of fasting and starvation comes from studies of vertebrates; however, for ethical reasons, studies that monitor vertebrates through the lethal endpoint are scant. Insects are convenient models to characterize the comparative strategies used to cope with starvation because they have diverse life histories and have evolved under the omnipresent challenge of food limitation. Moreover, we can study the physiology of starvation through its natural endpoint. In this study we raised populations of five species of insects (adult grasshoppers, crickets, cockroaches, and larval beetles and moths) on diets labeled with either 13C-palmitic acid or 13C-leucine to isotopically enrich the lipids or the proteins in their bodies, respectively. The insects were allowed to become postabsorptive and then starved. We periodically measured the δ13C of the exhaled breath to characterize how each species adjusted their reliance on endogenous lipids and proteins as energy sources. We found that starving insects employ a wide range of strategies for regulating lipid and protein oxidation. All of the insects except for the beetle larvae were capable of sharply reducing reliance on protein oxidation; however, this protein sparing strategy was usually unsustainable during the entire starvation period. All insects increased their reliance on lipid oxidation, but while some species (grasshoppers, cockroaches, and beetle larvae) were still relying extensively on lipids at the time of death, other species (crickets and moth larvae) allowed rates of lipid oxidation to return to prestarvation levels. Although lipids and proteins are critical metabolic fuels for both vertebrates and insects, insects apparently exhibit a much wider range of strategies for rationing these limited resources during starvation.

  16. Moralized Rationality: Relying on Logic and Evidence in the Formation and Evaluation of Belief Can Be Seen as a Moral Issue

    Science.gov (United States)

    Skitka, Linda J.

    2016-01-01

    In the present article we demonstrate stable individual differences in the extent to which a reliance on logic and evidence in the formation and evaluation of beliefs is perceived as a moral virtue, and a reliance on less rational processes is perceived as a vice. We refer to this individual difference variable as moralized rationality. Eight studies are reported in which an instrument to measure individual differences in moralized rationality is validated. Results show that the Moralized Rationality Scale (MRS) is internally consistent, and captures something distinct from the personal importance people attach to being rational (Studies 1–3). Furthermore, the MRS has high test-retest reliability (Study 4), is conceptually distinct from frequently used measures of individual differences in moral values, and it is negatively related to common beliefs that are not supported by scientific evidence (Study 5). We further demonstrate that the MRS predicts morally laden reactions, such as a desire for punishment, of people who rely on irrational (vs. rational) ways of forming and evaluating beliefs (Studies 6 and 7). Finally, we show that the MRS uniquely predicts motivation to contribute to a charity that works to prevent the spread of irrational beliefs (Study 8). We conclude that (1) there are stable individual differences in the extent to which people moralize a reliance on rationality in the formation and evaluation of beliefs, (2) that these individual differences do not reduce to the personal importance attached to rationality, and (3) that individual differences in moralized rationality have important motivational and interpersonal consequences. PMID:27851777

  17. Moralized Rationality: Relying on Logic and Evidence in the Formation and Evaluation of Belief Can Be Seen as a Moral Issue.

    Directory of Open Access Journals (Sweden)

    Tomas Ståhl

    Full Text Available In the present article we demonstrate stable individual differences in the extent to which a reliance on logic and evidence in the formation and evaluation of beliefs is perceived as a moral virtue, and a reliance on less rational processes is perceived as a vice. We refer to this individual difference variable as moralized rationality. Eight studies are reported in which an instrument to measure individual differences in moralized rationality is validated. Results show that the Moralized Rationality Scale (MRS is internally consistent, and captures something distinct from the personal importance people attach to being rational (Studies 1-3. Furthermore, the MRS has high test-retest reliability (Study 4, is conceptually distinct from frequently used measures of individual differences in moral values, and it is negatively related to common beliefs that are not supported by scientific evidence (Study 5. We further demonstrate that the MRS predicts morally laden reactions, such as a desire for punishment, of people who rely on irrational (vs. rational ways of forming and evaluating beliefs (Studies 6 and 7. Finally, we show that the MRS uniquely predicts motivation to contribute to a charity that works to prevent the spread of irrational beliefs (Study 8. We conclude that (1 there are stable individual differences in the extent to which people moralize a reliance on rationality in the formation and evaluation of beliefs, (2 that these individual differences do not reduce to the personal importance attached to rationality, and (3 that individual differences in moralized rationality have important motivational and interpersonal consequences.

  18. How and When Do Insects Rely on Endogenous Protein and Lipid Resources during Lethal Bouts of Starvation? A New Application for 13C-Breath testing.

    Directory of Open Access Journals (Sweden)

    Marshall D McCue

    Full Text Available Most of our understanding about the physiology of fasting and starvation comes from studies of vertebrates; however, for ethical reasons, studies that monitor vertebrates through the lethal endpoint are scant. Insects are convenient models to characterize the comparative strategies used to cope with starvation because they have diverse life histories and have evolved under the omnipresent challenge of food limitation. Moreover, we can study the physiology of starvation through its natural endpoint. In this study we raised populations of five species of insects (adult grasshoppers, crickets, cockroaches, and larval beetles and moths on diets labeled with either 13C-palmitic acid or 13C-leucine to isotopically enrich the lipids or the proteins in their bodies, respectively. The insects were allowed to become postabsorptive and then starved. We periodically measured the δ13C of the exhaled breath to characterize how each species adjusted their reliance on endogenous lipids and proteins as energy sources. We found that starving insects employ a wide range of strategies for regulating lipid and protein oxidation. All of the insects except for the beetle larvae were capable of sharply reducing reliance on protein oxidation; however, this protein sparing strategy was usually unsustainable during the entire starvation period. All insects increased their reliance on lipid oxidation, but while some species (grasshoppers, cockroaches, and beetle larvae were still relying extensively on lipids at the time of death, other species (crickets and moth larvae allowed rates of lipid oxidation to return to prestarvation levels. Although lipids and proteins are critical metabolic fuels for both vertebrates and insects, insects apparently exhibit a much wider range of strategies for rationing these limited resources during starvation.

  19. Stepped MS(All) Relied Transition (SMART): An approach to rapidly determine optimal multiple reaction monitoring mass spectrometry parameters for small molecules.

    Science.gov (United States)

    Ye, Hui; Zhu, Lin; Wang, Lin; Liu, Huiying; Zhang, Jun; Wu, Mengqiu; Wang, Guangji; Hao, Haiping

    2016-02-11

    Multiple reaction monitoring (MRM) is a universal approach for quantitative analysis because of its high specificity and sensitivity. Nevertheless, optimization of MRM parameters remains as a time and labor-intensive task particularly in multiplexed quantitative analysis of small molecules in complex mixtures. In this study, we have developed an approach named Stepped MS(All) Relied Transition (SMART) to predict the optimal MRM parameters of small molecules. SMART requires firstly a rapid and high-throughput analysis of samples using a Stepped MS(All) technique (sMS(All)) on a Q-TOF, which consists of serial MS(All) events acquired from low CE to gradually stepped-up CE values in a cycle. The optimal CE values can then be determined by comparing the extracted ion chromatograms for the ion pairs of interest among serial scans. The SMART-predicted parameters were found to agree well with the parameters optimized on a triple quadrupole from the same vendor using a mixture of standards. The parameters optimized on a triple quadrupole from a different vendor was also employed for comparison, and found to be linearly correlated with the SMART-predicted parameters, suggesting the potential applications of the SMART approach among different instrumental platforms. This approach was further validated by applying to simultaneous quantification of 31 herbal components in the plasma of rats treated with a herbal prescription. Because the sMS(All) acquisition can be accomplished in a single run for multiple components independent of standards, the SMART approach are expected to find its wide application in the multiplexed quantitative analysis of complex mixtures. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Book Review Who lives where. Habitability conditions of the population living in the great Andalusian cities / Reseña Del Libro Quién vive dónde. Las condiciones de habitabilidad de la población que vive en las grandes ciudades andaluzas

    Directory of Open Access Journals (Sweden)

    Diego Sánchez González

    2016-09-01

    Full Text Available Book Review Who lives where. Habitability conditions of the population living in the great Andalusian cities Reseña Del Libro Quién vive dónde. Las condiciones de habitabilidad de la población que vive en las grandes ciudades andaluzas

  1. Espacios exclusivos y excluyentes: ¿Cómo y quién habita el espacio público? El Boulevard Naciones Unidas (Quito y La Boca (Ciudad de Buenos Aires.

    Directory of Open Access Journals (Sweden)

    Kathrin Hopfgartner

    2014-12-01

    Full Text Available Desde finales del siglo XX, gobiernos locales de diferentes ciudades de América Latina implementan políticas urbanas de corte neoliberal. El objetivo es re-configurar ciudades económicamente productivas. Para ello, se busca el mejoramiento del factor de localización de estas a través de la atracción de visitantes e inversionistas. Con ello, se da el paso de una lógica de gobernanza urbano gerencial a “la ciudad empresarial”. Una de las implicaciones más significativas es el carácter selectivo que toman los espacios públicos. Concretamente, se los convierte en nuevas centralidades orientadas, fundamentalmente, al consumo de sectores de altos ingresos. Esto deriva en una producción del espacio público, que profundiza la polarización socio-económica y la configuración de ciudades fragmentadas y desiguales. Sin embargo, la producción de un determinado espacio se realiza tanto desde las políticas urbanas, como desde los actores del lugar. En este sentido, el espacio público es uno de los lugares en los cuales se materializa la tensión entre estas dos escalas. Tensión que se deriva a partir de la disputa por quien instalará los parámetros de cómo y quién podrá habitar y consumir el espacio público. En esta línea, el presente trabajo analiza la producción de espacios públicos en dos casos de estudios latinoamericanos: la construcción del Boulevard Naciones Unidas, en la ciudad de Quito, y la renovación urbana del barrio La Boca, en la Ciudad de Buenos Aires.

  2. An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells

    Science.gov (United States)

    Knies, Diana; Klobuch, Sebastian; Xue, Shao-An; Birtel, Matthias; Echchannaoui, Hakim; Yildiz, Oezlem; Omokoko, Tana; Guillaume, Philippe; Romero, Pedro; Stauss, Hans; Sahin, Ugur; Herr, Wolfgang; Theobald, Matthias; Thomas, Simone; Voss, Ralf-Holger

    2016-01-01

    Immunotherapy of cancer envisions the adoptive transfer of T-cells genetically engineered with tumor-specific heterodimeric α/β T-cell receptors (TCRα/β). However, potential mispairing of introduced TCRα/β-chains with endogenous β/α-ones may evoke unpredictable autoimmune reactivities. A novel single chain (sc)TCR format relies on the fusion of the Vα-Linker-Vβ-fragment to the TCR Cβ-domain and coexpression of the TCR Cα-domain capable of recruiting the natural CD3-complex for full and hence, native T-cell signaling. Here, we tested whether such a gp100(280-288)- or p53(264-272) tumor antigen-specific scTCR is still prone to mispairing with TCRα. In a human Jurkat-76 T-cell line lacking endogenous TCRs, surface expression and function of a scTCR could be reconstituted by any cointroduced TCRα-chain indicating mispairing to take place on a molecular basis. In contrast, transduction into human TCRα/β-positive T-cells revealed that mispairing is largely reduced. Competition experiments in Jurkat-76 confirmed the preference of dcTCR to selfpair and to spare scTCR. This also allowed for the generation of dc/scTCR-modified cytomegalovirus/tumor antigen-bispecific T-cells to augment T-cell activation in CMV-infected tumor patients. Residual mispairing was prevented by strenghtening the Vα-Li-Vβ-fragment through the design of a novel disulfide bond between a Vα- and a linker-resident residue close to Vβ. Multimer-stainings, and cytotoxicity-, IFNγ-secretion-, and CFSE-proliferation-assays, the latter towards dendritic cells endogenously processing RNA-electroporated gp100 antigen proved the absence of hybrid scTCR/TCRα-formation without impairing avidity of scTCR/Cα in T-cells. Moreover, a fragile cytomegalovirus pp65(495-503)-specific scTCR modified this way acquired enhanced cytotoxicity. Thus, optimized scTCR/Cα inhibits residual TCR mispairing to accomplish safe adoptive immunotherapy for bulk endogenous TCRα/β-positive T-cells. PMID:27028870

  3. Biological adhesion of the flatworm Macrostomum lignano relies on a duo-gland system and is mediated by a cell type-specific intermediate filament protein.

    Science.gov (United States)

    Lengerer, Birgit; Pjeta, Robert; Wunderer, Julia; Rodrigues, Marcelo; Arbore, Roberto; Schärer, Lukas; Berezikov, Eugene; Hess, Michael W; Pfaller, Kristian; Egger, Bernhard; Obwegeser, Sabrina; Salvenmoser, Willi; Ladurner, Peter

    2014-02-12

    Free-living flatworms, in both marine and freshwater environments, are able to adhere to and release from a substrate several times within a second. This reversible adhesion relies on adhesive organs comprised of three cell types: an adhesive gland cell, a releasing gland cell, and an anchor cell, which is a modified epidermal cell responsible for structural support. However, nothing is currently known about the molecules that are involved in this adhesion process. In this study we present the detailed morphology of the adhesive organs of the free-living marine flatworm Macrostomum lignano. About 130 adhesive organs are located in a horse-shoe-shaped arc along the ventral side of the tail plate. Each organ consists of exactly three cells, an adhesive gland cell, a releasing gland cell, and an anchor cell. The necks of the two gland cells penetrate the anchor cell through a common pore. Modified microvilli of the anchor cell form a collar surrounding the necks of the adhesive- and releasing glands, jointly forming the papilla, the outer visible part of the adhesive organs. Next, we identified an intermediate filament (IF) gene, macif1, which is expressed in the anchor cells. RNA interference mediated knock-down resulted in the first experimentally induced non-adhesion phenotype in any marine animal. Specifically, the absence of intermediate filaments in the anchor cells led to papillae with open tips, a reduction of the cytoskeleton network, a decline in hemidesmosomal connections, and to shortened microvilli containing less actin. Our findings reveal an elaborate biological adhesion system in a free-living flatworm, which permits impressively rapid temporary adhesion-release performance in the marine environment. We demonstrate that the structural integrity of the supportive cell, the anchor cell, is essential for this adhesion process: the knock-down of the anchor cell-specific intermediate filament gene resulted in the inability of the animals to adhere. The RNAi

  4. A Feminist Intervention That Hurt Women: Biological Differences, Ergonomics, and Occupational Health: Une intervention féministe qui a nui aux femmes: différences biologiques, égalité, ergonomie et santé au travail.

    Science.gov (United States)

    Messing, Karen

    2017-11-01

    The University of Québec in Montréal has agreements with trade unions providing access to university resources. Researchers involved in this program worked in partnership with union women's and health and safety committees for more than twenty years. Not all studies succeeded in improving women's working conditions. One joint project involved observational studies of tasks done by health-care workers, complemented by interviews and questionnaires. We found that task assignments, movements, postures, and work-related musculoskeletal disorders varied by gender/sex and made recommendations for change. However, issues of pay equity, spending on health care, and contracting-out of "ancillary work" were salient. Researchers learned that in the absence of changes in power relationships in the workplace, women may be disadvantaged by denial as well as by exaggeration of female-male differences. Men may also be at risk when their gender is invisible. We suggest some feminist approaches to workplace solutions and some pathways for research. Résumé L'Université du Québec à Montréal a signé avec des centrales syndicales des ententes leur donnant un accès à des ressources universitaires. Des chercheures ont travaillé en partenariat avec des comités syndicaux de condition des femmes et de santé-sécurité au travail pendant plus de 25 ans, mais ce ne sont pas toutes les études qui ont abouti à des améliorations. Un projet concernait des observations du travail d'employé.e.s du secteur de la santé, dont les tâches, mouvements, et postures variaient selon le genre/sexe. Nous avons recommandé des transformations, mais des enjeux d'équité salariale, de coûts et de sous-traitance y ont fait obstacle. Les chercheures ont appris qu'en l'absence de transformation des rapports de pouvoir au travail, le déni des différences hommes-femmes, autant que leur exagération, peut désavantager les travailleuses (et les travailleurs). Nous suggérons des approches f

  5. Qui représente qui ? Choix organisationnels, identités sociales et ...

    African Journals Online (AJOL)

    sulaiman.adebowale

    16 sept. 2006 ... recherche effectué au Sud-Cameroun depuis trois ans. .... secteur forestier sont passées par exemple en moins d'une décennie de 10 milliards de .... 1974, la Loi forestière n° 81/13 du 27 novembre 1981, et de nombreux pas-.

  6. La concurrence des experts. Ou qui a le droit de dire ce qu’est la “traite des blanches” dans l’Allemagne de Weimar Competition Among Experts. Or who has the Right to say what Constitutes “White Slavery” in Weimar Germany

    Directory of Open Access Journals (Sweden)

    Benoît Majerus

    2011-03-01

    Full Text Available A travers une polémique qui éclate en 1929 dans le milieu associatif et social juif de la république de Weimar, cet article s’intéresse à la problématique de la constitution de l’expertise. A l’époque, différents acteurs s’opposent, chacun prétendant avoir la légitimité de “dire la vérité” à propos de la traite des blan­ches en Allemagne. Le “champ de la connaissance”, composé d’auteurs issus des sciences humaines comme Max Kreutzberger, s’oppose au “champ de l’ex­périence”, composé de personnes qui travaillent dans des associations juives et qui essayent d’établir un lien entre traite, prostitution et combat moral. Cette po­lémique constitue un cas d’étude révélateur des tensions qui naissent lors de la construction d’un savoir social sur la prostitution dans l’entre-deux-guerres.Through a polemic which broke out in 1929 in the Jewish associative and social medium of the Weimar Republic, this article looks into the problematic of establishing expertise. At the time, various contending actors each claimed to have legitimacy, “to know the truth” about white slavery in Germany. The “field of savants”, composed of authors issuing from the human sciences - like Max Kreutzberger, were opposed by the “the experimental field”, composed of people working in Jewish associations that tried to establish a bond between slavery, prostitution and moral combat. This polemic is a revealing case study of the tensions which arose in the development of social knowledge on prostitution in the inter-war period.

  7. Le volcan Cayambe (Equateur: son activité au cours des 5000 dernières années et les menaces qui en résultent

    Directory of Open Access Journals (Sweden)

    1996-01-01

    Full Text Available L’étude des produits récents émis par les dômes dacitiques qui constituent la partie sommitale du volcan Cayambe, situé à 60 km au NE de Quito, révèle quatre unités volcaniques comprenant des coulées pyroclastiques à blocs et cendres, des déferlantes et des lahars associés. La plus jeune de ces unités a été émise vers 360 ans BP. Par ailleurs, l’étude des dépôts d’une tourbière du Cayambe met en évidence 23 niveaux de retombées (cendres et lapilli émis au cours de 3 grands cycles d’activité, de 7 à 10 siècles de durée, depuis 4 000 ans. Le dernier de ces cycles, auquel peuvent être rattachées les quatre phases de coulées pyroclastiques, n’est peut-être pas terminé, comme le suggère une petite éruption intervenue en 1785-1786. Ces résultats donnent un éclairage nouveau sur les menaces que ce volcan, fortement englacé, fait peser sur les populations vivant à son pied. EL VOLCÁN CAYAMBE (ECUADOR: SU ACTIVIDAD DESDE LOS ÚLTIMOS 5 000 AÑOS Y LAS AMENAZAS CORRESPONDIENTES. El estudio de los productos recientes emitidos por los domos dacíticos que forman la cumbre del volcán Cayambe, ubicado a 60 km al noreste de Quito, revela cuatro unidades de flujos piroclásticos de bloques y ceniza, oleadas y lahares asociados. La unidad más reciente fue emitida alrededor de 360 BP. Además, el estudio de los depósitos de una turbera del Cayambe muestra 23 niveles de caídas (cenizas y lapilli, que corresponden a tres ciclos de actividad, de 7 a 10 siglos de duración cada uno, durante los 4 000 últimos años. El último ciclo, que incluye las cuatro unidades de flujos piroclásticos mencionadas, puede no haber terminado todavía, como lo sugiere la pequeña erupción ocurrida en 1785-1786. Estos resultados enfatizan el peligro que este volcán, cubierto por un espeso casquete glaciar, puede representar para las poblaciones y las infraestructuras establecidas en sus alrededores. CAYAMBE VOLCANO (ECUADOR: ERUPTIVE

  8. Factors Influencing Self-Regulation in E-learning 2.0: Confirmatory Factor Model | Facteurs qui influencent la maîtrise de soi en cyberapprentissage 2.0 : modèle de facteur confirmative

    Directory of Open Access Journals (Sweden)

    Hong Zhao

    2016-04-01

    éterminants environnementaux jouent un rôle clé pour modeler la maîtrise de soi dans le processus d’apprentissage. Cet article rapporte une étude sur les influences de l’environnement de cyberapprentissage 2.0 sur la maîtrise de soi. L’étude a cerné les facteurs qui, dans un tel environnement, influencent la maîtrise de soi et déterminent les relations entre les facteurs et la maîtrise de soi. Un modèle théorique de catégorisation des facteurs de réussite pour l’apprentissage autogéré a été proposé pour ce type d’environnement. Un questionnaire a été conçu selon ce modèle et plus de deux cent cinquante élèves en téléapprentissage à Beijing et à Hong Kong y ont répondu. À l’aide d’une technique de modélisation par équation structurelle, les relations entre les facteurs environnementaux et l’autogestion ont été analysées. Les résultats statistiques ont démontré que plusieurs facteurs affectent l’autogestion dans l’environnement de cyberapprentissage 2.0. Ceux-ci comprennent la qualité du système, la qualité de l’information, la qualité du service et la satisfaction de l’usager.

  9. Sabiedriskās attiecības jauno reliģisko kustību praksē. Baznīcas "Jaunā paaudze" gadījuma analīze

    OpenAIRE

    Maļuha, Sandra

    2008-01-01

    Izstrādātā bakalaura darba nosaukums ir „Sabiedriskās attiecības jauno reliģisko kustību praksē: baznīcas „Jaunā paaudze” gadījuma analīze”. Darbā aplūkotā pētnieciskā problēma ir jauns, līdz šim maz pētīts fenomens - sabiedrisko attiecību mērķu realizācija jauno reliģisko kustību darbībā. Izvēlētais pētniecības objekts ir baznīca „Jaunā paaudze”, kura, pēc Tieslietu ministrijas Reliģisko lietu pārvaldes sniegtajiem datiem, šobrīd ir lielākā jaunā reliģiskā kustība Latvijā. Teorētiskā pama...

  10. Instability and Related Macroscopic Effects in Toroidal Discharges; Instabilites et Effets Macroscopiques qui les Accompagnent dans les Decharges Toroidales; Neustojchivost' i svyazannye s nej makroskopicheskie ehffekty v toroidal'nykh razryadakh; Inestabilidad y Efectos Macroscopicos Conexos, en las Descargas Toroidales

    Energy Technology Data Exchange (ETDEWEB)

    Kadomcev, B. B.; Pogutse, O. P. [Institut Atomnoj Ehnergii Im. I.V. Kurchatova, Moskva, SSSR (Russian Federation)

    1966-04-15

    . The interaction of the drift oscillations and the convection cells is also discussed. (author) [French] Le memoire a pour objet l'examen, d'un point de vue commun, des types principaux d'instabilite de plasma dans les decharges toroidales, ainsi qui des effets macroscopiques causes par les oscillations non lineaires du plasma dues aux instabilites. Les auteurs examinent d'abord le probleme lineaire de la stabilite de la decharge symetrique par rapport a l'axe (on tient compte de la forme toroiedale en imposant des conditions limites aux jonctions des faces) en se fondant sur une equation cinetique qui tient compte des collisions du caractere fini du rayon de Larmor des ions, et ils donnent une classification des instabilites. Les resultats de la solution du probleme lineaire servent de base pour l'examen ulterieur des processus non lineaires dans la decharge. Lors de l'examen du probleme non lineaire, les auteurs accordent une importance particuliere au cas le plus simple de la decharge dans un champ magnetique longitudinal intense avec une pression du plasma sensiblement inferieure a la pression magnetique. Si l'on neglige la non-potentialite des oscillations, il ne reste que deux instabilites - l'instabilite de derive et l'instabilite a convection de courant. Les auteurs montrent que l'instabilite a convection de courant entraine la formation d'un grand nombre de cellules de convection, dans lesquelles la chaleur se transmet par convection. Dans le cas d'un champ magnetique tres intense, les cellules de convection se recouvrent l'une l'autre et les flux macroscopiques de chaleur et de particules peuvent exceder dans une grande mesure les flux classiques, determines par des collisions binaires. En cas d'augmentation de la pression du plasma, les cellules de convection ne se recouvrent plus et l'effet macroscopique de l'instabilite a convection de courant devient plus faible. Si la pression du plasma croit encore, les oscillations instables deviennent non

  11. ¿Para quién publicamos? La producción académica de la investigación cualitativa en salud en el contexto de las políticas oficiales y universitarias en ciencia, tecnología e innovación

    OpenAIRE

    Cristancho Marulanda, Sergio; Posada Zapata, Isabel Cristina

    2015-01-01

    La pregunta sobre para quién(es) publicamos los resultados de la investigación cualitativa en salud en el contexto de las políticas oficiales y universitarias en ciencia, tecnología e innovación (cti) lleva a plantear un debate reflexivo con los siguientes objetivos 1) analizar las implicaciones que tienen para la producción académica de la investigación cualitativa en salud (ics) las políticas, normativas y sistemas de estímulo actuales, proyectados a nivel oficial y universitario en ciencia...

  12. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial.

    Science.gov (United States)

    Wallentin, Lars; Yusuf, Salim; Ezekowitz, Michael D; Alings, Marco; Flather, Marcus; Franzosi, Maria Grazia; Pais, Prem; Dans, Antonio; Eikelboom, John; Oldgren, Jonas; Pogue, Janice; Reilly, Paul A; Yang, Sean; Connolly, Stuart J

    2010-09-18

    Effectiveness and safety of warfarin is associated with the time in therapeutic range (TTR) with an international normalised ratio (INR) of 2·0-3·0. In the Randomised Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial, dabigatran versus warfarin reduced both stroke and haemorrhage. We aimed to investigate the primary and secondary outcomes of the RE-LY trial in relation to each centre's mean TTR (cTTR) in the warfarin population. In the RE-LY trial, 18 113 patients at 951 sites were randomly assigned to 110 mg or 150 mg dabigatran twice daily versus warfarin dose adjusted to INR 2·0-3·0. Median follow-up was 2·0 years. For 18 024 patients at 906 sites, the cTTR was estimated by averaging TTR for individual warfarin-treated patients calculated by the Rosendaal method. We compared the outcomes of RE-LY across the three treatment groups within four groups defined by the quartiles of cTTR. RE-LY is registered with ClinicalTrials.gov, number NCT00262600. The quartiles of cTTR for patients in the warfarin group were: less than 57·1%, 57·1-65·5%, 65·5-72·6%, and greater than 72·6%. There were no significant interactions between cTTR and prevention of stroke and systemic embolism with either 110 mg dabigatran (interaction p=0·89) or 150 mg dabigatran (interaction p=0·20) versus warfarin. Neither were any significant interactions recorded with cTTR with regards to intracranial bleeding with 110 mg dabigatran (interaction p=0·71) or 150 mg dabigatran (interaction p=0·89) versus warfarin. There was a significant interaction between cTTR and major bleeding when comparing 150 mg dabigatran with warfarin (interaction p=0·03), with less bleeding events at lower cTTR but similar events at higher cTTR, whereas rates of major bleeding were lower with 110 mg dabigatran than with warfarin irrespective of cTTR. There were significant interactions between cTTR and effects of both 110 mg and 150 mg dabigatran versus warfarin on the composite of all

  13. Does the Spatial Distribution of the Parasitic Mite Varroa jacobsoni Oud. (Mesostigmata: Varroidae) in Worker Brood of Honey Bee Apis Mellifera L. (Hymenoptera: Apidae) Rely on an Aggregative Process?

    Science.gov (United States)

    Salvy, M.; Capowiez, Y.; Le Conte, Y.; Salvy, M.; Clément, J.-L.

    Varroa jacobsoni is an ectoparasite of honey bees which reproduces in capped brood cells. Multi-infestation is frequently observed in worker brood and can be interpreted as an aggregative phenomenon. The aim of this study was to determine whether the distribution of V. jacobsoni in worker brood cells relies on a random or an aggregative process. We studied the distribution of Varroa females in capped worker brood at similar age by comparing, by a Monte Carlo test, the observed frequency distribution of mites per cell to simulated distributions based on a random process. A complementary approach, using the "nearest neighbor distances" (NND) with Monte Carlo tests, was investigated to study the spatial distribution (a) between mites in different cells and (b) between infested cells in brood. The observed distributions did not differ significantly from that expected by a random process, and we conclude that there is no aggregation during invasion of V. jacobsoni in worker brood.

  14. Jeremy Rifkin, La troisième révolution industrielle. Comment le pouvoir latéral va transformer l’énergie, l’économie et le monde, Paris, Les Liens qui Libèrent, 2012, 414p.

    OpenAIRE

    Noé, Adam

    2013-01-01

    Certes, Jeremy Rifkin n’est pas aidé. « Prophète » pour les uns, « gourou » selon d’autres : difficile de croire que les qualificatifs qui lui sont ainsi destinés, parfois avec les meilleures intentions, ne soient pas, en d’autres milieux, empreints de connotations dépréciatives, fleurant bon la promotion de soi, le marketing médiatique et, pourquoi ne pas le dire, un certain charlatanisme. Il est vrai, Rifkin ne s’aide pas lui-même. Vraiment, a-t-on besoin d’anecdotes du genre : « La chancel...

  15. Spatial imagery relies on a sensory independent, though sensory sensitive, functional organization within the parietal cortex: a fMRI study of angle discrimination in sighted and congenitally blind individuals.

    Science.gov (United States)

    Bonino, Daniela; Ricciardi, Emiliano; Bernardi, Giulio; Sani, Lorenzo; Gentili, Claudio; Vecchi, Tomaso; Pietrini, Pietro

    2015-02-01

    Although vision offers distinctive information to space representation, individuals who lack vision since birth often show perceptual and representational skills comparable to those found in sighted individuals. However, congenitally blind individuals may result in impaired spatial analysis, when engaging in 'visual' spatial features (e.g., perspective or angle representation) or complex spatial mental abilities. In the present study, we measured behavioral and brain responses using functional magnetic resonance imaging in sighted and congenitally blind individuals during spatial imagery based on a modified version of the mental clock task (e.g., angle discrimination) and a simple recognition control condition, as conveyed across distinct sensory modalities: visual (sighted individuals only), tactile and auditory. Blind individuals were significantly less accurate during the auditory task, but comparable-to-sighted during the tactile task. As expected, both groups showed common neural activations in intraparietal and superior parietal regions across visual and non-visual spatial perception and imagery conditions, indicating the more abstract, sensory independent functional organization of these cortical areas, a property that we named supramodality. At the same time, however, comparisons in brain responses and functional connectivity patterns across experimental conditions demonstrated also a functional lateralization, in a way that correlated with the distinct behavioral performance in blind and sighted individuals. Specifically, blind individuals relied more on right parietal regions, mainly in the tactile and less in the auditory spatial processing. In sighted, spatial representation across modalities relied more on left parietal regions. In conclusions, intraparietal and superior parietal regions subserve supramodal spatial representations in sighted and congenitally blind individuals. Differences in their recruitment across non-visual spatial processing in

  16. An Investigation on the impact of using problem-based trainings in the in-service courses on the teachers' performance and capabilities, by relying on the elementary sixth grade mathematics book (case study: the city of Ahvaz

    Directory of Open Access Journals (Sweden)

    Pari Cheraq

    2017-02-01

    Full Text Available Changes in the administrative structure of the education system and the need to coordinate with the world of science and technology and hence, the need to update the general and technical information and knowledge, have doubled the importance and necessity of holding the new and efficient in-service trainings for the teachers. In this study, the attempt was taken to examine and analyze the impact of using problem-based trainings during the in-service courses on the teachers' performance and capabilities, by relying on the mathematics book of the sixth grade elementary level (case study: the city of Ahvaz. To do so, using a quasi-experimental study, 37 teachers of the sixth grade were selected from the elementary schools of Ahvaz city. For the in-service training courses on the teaching of mathematics, the problem-based learning method was used. After conducting the problem-based teaching method and the traditional method of teaching, through using the test and the standard questionnaire, the data about the teaching practice and the capabilities of the teachers were collected. Using t-test for the paired and independent samples, it was demonstrated that the problem-based in-service trainings, enhance the teachers' capabilities and performance regarding the problem-solving skills.

  17. Des recherches qui favorisent la participation et l'autonomisation

    International Development Research Centre (IDRC) Digital Library (Canada)

    et des enfants. • Reconnaissant le rôle que les femmes chercheures peuvent jouer dans la recherche en agriculture, le Fonds a soutenu la formation universitaire de 82 jeunes ... la nutrition et les régimes alimentaires;. • la mise au point d'une nouvelle ... sont dévolues aux femmes en agriculture et à faire en sorte que les ...

  18. Who decides what, when, how?; Qui decide quoi, quand, comment?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The law from December 30, 1991, precisely defines 3 axes of researches for the management of high level and long-lived radioactive wastes: separation/transmutation, surface storage and underground disposal. A global evaluation report about these researches is to be supplied in 2006 by the French government to the Parliament. A first synthesis of the knowledge gained after 14 years of research has led the national commission of the public debate (CNDP) to organize a national debate about the general options of management of high-level and long-lived radioactive wastes before the 2006 date line. The debate comprises 4 public hearings (September 2005: Bar-le-Duc, Saint-Dizier, Pont-du-Gard, Cherbourg), 12 round-tables (October and November 2005: Paris, Joinville, Caen, Nancy, Marseille), a synthesis meeting (December 2005, Dunkerque) and a closing meeting (January 2006, Lyon). This document is the synthesis of the round table debates which took place at Marseille. The main discussions of this session concerns the decision making in nuclear wastes management and the use of public funds for the management of radioactive wastes today and tomorrow. (J.S.)

  19. Des recherches qui favorisent la participation et l'autonomisation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    enrichissement des sols et des semences permet d'améliorer la nutrition · Les Nigérianes améliorent leur sort grâce aux légumes indigènes · L'élevage de la poule indigène, gage de résilience pour les agricultrices du Kenya.

  20. Dominio informativo, ¿quién tiene el poder?

    Directory of Open Access Journals (Sweden)

    César Mauricio Velásquez

    2004-01-01

    Full Text Available A través de la historia, las relaciones entre los gobiernos y la prensa han sido definitivas en el éxito o fracaso de quienes ostentan el poder. No es extraño que algunos jefes de Estado se sientan incómodos con la manera de informar de algunos medios o, por el contrario, decidan aliarse para estructurar determinadas agendas que se manejan de manera unánime para orientar el temario que decida el ejecutivo. El Observatorio de Medios de la Facultad de Comunicación Social y Periodismo realizó un estudio para conocer el estado de la relación entre el presidente Álvaro Uribe Vélez y la prensa. La investigación reveló presiones directas e indirectas que el gobierno ejerce sobre los periodistas.

  1. Adaptation aux changements climatiques en ce qui concerne l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2012-01-31

    First [1st] Country†Wise Inception Workshop of Stakeholders †Sudan, January 31, 2012, Sharija Conference Hall, Khartoum, Sudan. Download PDF. Journal articles. Maize cultivar specific parameters for decision support system for agrotechnology transfer (DSSAT) application in Tanzania. Download PDF. Studies.

  2. Le microdosage des engrais, une innovation qui profite aux femmes

    International Development Research Centre (IDRC) Digital Library (Canada)

    non seulement une diminution de leurs revenus, mais doivent aussi composer avec une pénurie chronique de céréales. Au Niger, par exemple, 2,5 millions de personnes ont eu besoin d'une aide alimentaire en 2005, par suite d'une grave sécheresse (PAM, 2010). Cette situation s'est reproduite en 2010, la mauvaise.

  3. Comment choisir ce qui aura été?

    DEFF Research Database (Denmark)

    Wilson, Alexander

    2015-01-01

    Many have invoked the nihilism that is endemic of the age we call the anthropocene. Bernard Stiegler has articulated this sentiment by highlighting how anthropocene films are typically nihilistic, for example, Von Trier’s Melancholia. But if the age is characterized by a cultural pessimism about...

  4. Ege bölgesi standart süreli yıllık maksimum yağışları için en uygun dağılımlar

    Directory of Open Access Journals (Sweden)

    Halil Karahan

    2013-03-01

    Full Text Available Su kaynaklarının temel girdisi olan yağışların; miktarı, süresi, şiddeti, alansal ve zamansal değişimi v.b. özelliklerinin bilinmesi; su kaynakları, tarım, kentleşme, drenaj, taşkın kontrolü ve ulaşım gibi farklı sektörlere ait planlama, tasarım, inşaat ve işletme çalışmaları için gereklidir. Belirtilen faaliyetlerin gerçekleştirilebilmesi için; mevcut gözlemlere dayalı, güvenilir ve gerçekçi tahminlerin yapılması gerekir. Güvenilir tahmin yapabilmenin ilk aşaması ise mevcut gözlemlerin güvenirliğinin test edilmesidir. Bu çalışmada; DMİ Genel Müdürlüğü tarafından işletilen Ege Bölgesi il ve ilçe merkezlerinde yer alan meteoroloji istasyonlarında (1929-2005 yıllarında ölçülen standart süreli maksimum yağış değerlerinin hangi dağılıma uyduklarını belirlemek için; Kolmogorov-Smirnov, Anderson-Darling ve Ki-Kare dağılım uygunluk testleri uygulanmıştır. Anderson-Darling testine göre gözlemlerin tümüne yakını GEV dağılımına uyum gösterirken, Kolmogorov-Smirnov ve Ki-Kare testlerine göre kısa, orta ve uzun süreli yağış gözlemleri için genellikle GEV, Gamma ve Log-Normal dağılımın uygun olduğu görülmüştür. Seçilen olasılık dağılımının parametrelerini belirlemek için farklı dağılımlara göre maksimum olabilirlik (LN2, LN3, EXP2, Gamma3, olasılık-ağırlıklı momentler (LP3,Gamma2, L-momentler (GEV ve en küçük kareler (Weibull2 yöntemleri kullanılmıştır.

  5. Des vies en marges : le mal-être qui fait irruption et qui différencie

    Directory of Open Access Journals (Sweden)

    Raffaella Sette

    2015-05-01

    The article deals with the socio-demographic data of the protagonists, motives and contexts of crimes, aggravating and attenuating circumstances and the role of media and institutions. Finally, the author, using Sellin’s definitions of cultural conflicts, reflects on policies related to the protection of women in Italy.

  6. Haber Üretiminde Göreli Özerklik Problemi: Bir Saha Araştırması / The Relative Autonomy Problem in Newsmaking Process: A Field Research

    Directory of Open Access Journals (Sweden)

    Deniz Tansel İLİC

    2014-09-01

    Full Text Available Kültürel simgelerin üretim sürecinde görev yapan enformasyon işçilerinin özerkliği, sosyal bilimler açısından önemli bir tartışma konusudur. Üretim sürecini sadece sahiplik üzerinden değerlendiren yaklaşımlar, mülkiyet ilişkilerinin, simge üreticisinin özerklik alanını tamamen kısıtlayacağını savunurlar. Yine de, zihinsel emekleri ile çalışan simge üreticilerinin, belli oranda özerkliğe sahip olduğu iddiası sınamaya değerdir. Bu çalışmada, David Hesmondhalgh ve Mike Wayne’deki göreli özerklik vurgusundan yola çıkarak, Türkiye’de anaakım televizyon haberciliğinde bir saha araştırması yapılmıştır. Fox TV, TGRT Haber ve Kanal D’de gerçekleştirilen katılımlı gözlemlerle, birer simge üreticisi olan habercilerin, hangi oranda özerk oldukları saptanmaya çalışılmıştır. / The autonomy of information workers who work in the production process of cultural symbols is an important issue for social sciences. The approaches that evaluate the production process only in the context of ownership claim that these relationships will restrain the autonomy field of the symbol producer. Still the suggestion that symbol producers who work with their mental labours have a certain amount of autonomy is worth testing. In this study a field research is conducted in mainstream broadcasting in Turkey by using the relative autonomy emphasis in David Hesmondhalgh and Mike Wayne as a starting point. In the participant observation that is conducted in Fox TV, TGRT Haber and Kanal D Televisions it is tried to determine at what level the journalists as symbol producers are autonomous.

  7. Early LC3 lipidation induced by d-limonene does not rely on mTOR inhibition, ERK activation and ROS production and it is associated with reduced clonogenic capacity of SH-SY5Y neuroblastoma cells.

    Science.gov (United States)

    Berliocchi, Laura; Chiappini, Carlotta; Adornetto, Annagrazia; Gentile, Debora; Cerri, Silvia; Russo, Rossella; Bagetta, Giacinto; Corasaniti, Maria Tiziana

    2018-02-01

    d-Limonene is a natural monoterpene abundant in Citrus essential oils. It is endowed with several biological activities, including inhibition of carcinogenesis and promotion of tumour regression. Recently, d-limonene has been shown to modulate autophagic markers in vitro at concentrations found in vivo, in clinical pharmacokinetic studies. Autophagy is an intracellular catabolic process serving as both an adaptive metabolic response and a quality control mechanism. Because autophagy defects have been linked to a wide range of human pathologies, including neurodegeneration and cancer, there is a need for new pharmacological tools to control deregulated autophagy. To better understand the effects of d-limonene on autophagy, to identify the molecular mechanisms through which this monoterpene rapidly triggers LC3 lipidation and to evaluate the role for autophagy in long-term effects of d-limonene. Human SH-SY5Y neuroblastoma, HepG2 hepatocellular carcinoma and MCF7 breast cancer cells were used. Endogenous LC3-II levels were evaluated by western blotting. Autophagic flux assay was performed using bafilomycin A1 and chloroquine. Intracellular distribution of LC3 protein was studied by confocal microscopy analysis of LC3B-GFP transduced cells. Expression of lysosomal-membrane protein LAMP-1 was assessed by immunofluorescence analysis. Phosphorylated levels of downstream substrates of mTOR kinase (p70S6 kinase, 4E-BP1, and ULK1) and ERK were analyzed by western blotting. Production of reactive oxygen species (ROS) was assessed by live confocal microscopy of cells loaded with CellROX ® Green Reagent. Clonogenic assay was used to evaluate the ability of treated cells to proliferate and form colonies. LC3 lipidation promoted by d-limonene correlates with autophagosome formation and stimulation of basal autophagy. LC3 lipidation does not rely on inhibition of mTOR kinase, which instead appears to be transiently activated. In addition, d-limonene rapidly activates ERK and

  8. Deriving Empirically-Based Design Guidelines for Advanced Learning Technologies that Foster Disciplinary Comprehension / Définir des lignes directrices fondées sur des données empiriques pour les technologies d’apprentissage avancé qui favorisent la compr

    Directory of Open Access Journals (Sweden)

    Eric Poitras

    2012-02-01

    Full Text Available Planning, conducting, and reporting leading-edge research requires professionals who are capable of highly skilled reading. This study reports the development of an empirically informed computer-based learning environment designed to foster the acquisition of reading comprehension strategies that mediate expertise in the social sciences. Empirical data were gathered in a mixed-methods explanatory sequential design that examined the reading comprehension strategies used by an expert social scientist while reading a professional-level text. Process data were collected through a concurrent think-aloud protocol and coded according to reading comprehension processes. We combined both quantitative and qualitative analyses to identify, describe, and explain patterns in the expert’s use of reading strategies. Our findings indicate that highly-skilled reading is characterized by critiquing text information, relating information to prior knowledge, and evaluating one’s own understanding of text information. Findings are used to inform the design of worked-examples and a pedagogical agent embedded within the Highly-Skilled Reading Tutor. Le type de planification, de réalisation et l’analyse qui caractérise une recherche d’avant-garde nécessite des professionnels en mesure d’effectuer des lectures hautement spécialisées. La présente étude dresse un rapport sur l’élaboration d’un milieu d’apprentissage informatisé conçu pour favoriser l’acquisition de stratégies de compréhension en lecture permettant d’assurer la transmission des connaissances spécialisées en sciences sociales. La collecte de données empiriques s’est effectuée suivant une conception séquentielle explicative fondée sur une méthode mixte, qui étudiait les stratégies de compréhension de lecture utilisées par un expert en sciences sociales lors de sa lecture d’un texte de calibre professionnel. La collecte des données sur le processus s

  9. Evaluation of the Use of Periodicals Collection of the Higher Education Council Documentation and Online Search Center: Arts and Humanities Periodicals YÖK Dokümantasyon ve Uluslararası Bilgi Tarama Merkezi Koleksiyonundaki Sanat ve Beşeri Bilimler Konulu Süreli Yayınların Kullanım Değerlendirmesi

    Directory of Open Access Journals (Sweden)

    Elçin Özbudak

    1995-06-01

    Full Text Available Evaluation of the use perodicals collections in libraries is important as perodicals report the results of the latest scientific research and they are usually more expensive than other types of library materials. In this study we evaluate the use of Arts and Humanities periodicals in the collection of the Higher Education Council Documentation Center. Although the use of Arts and Humanities periodicals was found to be lower than, say, Biomedical periodicals collection, the number of journal titles in Arts and Humanities appears to be quite satisfactory. Some suggestions are made so as to increase the use of Arts and Humanities periodicals collection. Bilimsel araştırmalar için en güncel bilgileri veren ve maliyeti diğer materyallere göre daha fazla olan süreli yayınların ne oranda kullanıldığının araştırılması, koleksiyon değerlendirmesi açısından önemlidir. Bu amaçla, Yükseköğretim Kurulu Dokümantasyon ve Uluslararası Bilgi Tarama Merkezi süreli yayınlar koleksiyonunun genel bir değerlendirmesi yapılarak "Sanat ve Beşeri Bilimler" konulu süreli yayınların kullanımları incelenmiş, Yükseköğretim Kurulu Dokümantasyon ve Uluslararası Bilgi Tarama Merkezi 'nde önemli ve büyük bir süreli yayınlar koleksiyonu bulunduğu, "Sanat ve Beşeri Bilimler" konulu süreli yayınların da yeterli olduğu sonuçları çıkartılmıştır. "Sanat ve Beşeri Bilimler" konulu süreli yayınların kullanımlarının nispeten düşük oluşu, bu alanda çalışan araştırmacıların süreli yayınlara yeterince ilgi göstermemelerine bağlanarak, kullanımı artırmak için öneriler getirilmiştir.

  10. La spirale dell’azzardo: una subcultura del gioco che “evapora” le relazioni / La spirale du jeu de hasard : une sous-culture qui empêche toute relation / The gambling: a subculture of game that “burns” the relationships

    Directory of Open Access Journals (Sweden)

    Molin Valentina

    2011-07-01

    neutralizzazione dei possibili rinforzi negativi che provengono invece dai “non-giocatori”.Dans cet article, l’auteur analyse les caractéristiques de ce qu’elle a appelé « sous-culture des jeux de hasard », décelable dans certains milieux de loisirs et dans les sous-groupes de joueurs particulièrement « acharnés ». Parmi ces formes de sous-culture, l’article va identifier les règles et les sanctions, les valeurs, les comportements durables, la caractérisation des relations et des interactions, en concluant que ce qui est construit dans l'espace du jeu est un univers séparé, une «réalité extérieure» dans laquelle des nouvelles règles sont écrites et où les valeurs changent par rapport au «monde extérieur» . Il a également été possible de conclure que l'adhésion à l' «univers du jeu» - l'internalisation de ses normes, le partage de ses valeurs, le développement des relations en son sein - est un facteur de maintenance de la conduite du jeu, car cette adhésion permet d'envisager comme «normal» son propre comportement grâce à des réactions positives provenant des compagnons de jeu et à la neutralisation d’éventuelles réactions négatives provenant des «non joueurs».

  11. From malnutrition to HIV: spirulina is an effective solution which continues to reveal its secrets De la malnutrition au VIH : la spiruline arme efficace qui n’en finit pas de livrer ses secrets De la malnutrición al VIH: la espirulina como arma eficaz que no cesa de revelar secretos

    Directory of Open Access Journals (Sweden)

    Raphaëlle Birot

    2012-04-01

    Full Text Available Spirulina presents major advantages in the fight against chronic malnutrition based on its micronutrient composition, its health potential and the fact that it can be grown locally. International solidarity associations, such as Antenna Technologies and Entrepreneurs du Monde whose goal is to reduce extreme poverty and public health problems in developing countries, have undertakenproduction and distribution programmes of spirulina, especially in West Africa. The quality of spirulina produced in these developing countries continues to increase to the extent that it can now be exported. Thus, associations such as Spirulidaire market a traditional, fair and supportive spirulina in France and Europe and thus promote local producers.The perception of spirulina continues to evolve with the multiplication of field initiatives and the accumulation of scientific data. New studies demonstrate that spirulina also presents clinically significant anti-viral and immuno-stimulating effects in people infected by HIV.Sur la base de sa composition en micronutriments, de son potentiel pour la santé et du fait qu’elle soit cultivable localement, la spiruline présente des avantages majeurs dans la lutte contre la malnutrition chronique. Des associations de solidarité internationale, comme Antenna Technologies et Entrepreneurs du Monde qui ont comme vocation de réduire l’extrême pauvreté et les problèmes de santé publique dans les pays en développement, ont entrepris des programmes de culture et de distribution de spiruline notamment en Afrique de l’Ouest. La qualité de la spiruline produite dans ces pays en développement ne cesse d’augmenter et est telle qu’elle permet son exportation. C’est ainsi que des associations comme Spirulidaire commercialisent une spiruline artisanale, équitable et solidaire en France et en Europe et permettent ainsi de soutenir les producteurs locaux.La perception de la spiruline ne cesse d’évoluer avec la

  12. Quem são os egressos de internação psiquiátrica? ¿Quiénes son los pacientes que obtuvieron el alta de la internación psiquiátrica? Who are the patients who have been discharged from psychiatric hospital care recently?

    Directory of Open Access Journals (Sweden)

    Lucilene Cardoso

    2009-12-01

    Full Text Available Objetivo: Conhecer quem são, hoje, as pessoas com transtornos mentais que tiveram alta hospitalar de internação psiquiátrica recente, e quais suas características comuns. Método: Pesquisa quantitativa descritiva realizada no período: 17/12/2007 a 17/04/08, através de questionário acerca das variáveis sociodemográficas, internações anteriores e conhecimento de 48 pacientes quanto ao diagnóstico e tratamento psicofarmacológico. Resultados: A média de idade foi 39 anos e 30 pacientes eram mulheres. Diagnósticos de Esquizofrenia e Transtornos Esquizotípicos foram prevalentes em 33,3% da amostra. Não souberam dizer qual era seu diagnóstico 56% da amostra, e apenas 43,8% souberam dizer corretamente nomes e dosagens dos medicamentos. Tinham pelo menos uma internação psiquiátrica anterior 62,5% deles. Conclusões: Conhecer quem são esses pacientes possibilita identificar características que podem fomentar a determinação do melhor tratamento, suporte profissional e elaboração de intervenções psicoeducativas que demonstraram ser necessárias a essa população.Objetivo: Conocer quiénes son, hoy, las personas con trastornos mentales que obtuvieron el alta hospitalaria de internación psiquiátrica reciente, y cuáles son sus características comunes. Métodos: Investigación cuantitativa descriptiva en el período: 17/12/2007 a 17/04/08, a través de cuestionario acerca de las variables sociodemográficas, internaciones anteriores y conocimiento de los pacientes en lo que se refiere al diagnóstico y tratamiento psicofarmacológico. Resultados: Fueron entrevistados 48 pacientes. El promedio de edad fue 39 años y 30 pacientes eran mujeres. Diagnósticos de Esquizofrenia y Trastornos Esquizoides prevalecieron en 33,3% de la muestra. No supieron decir cuál era su diagnóstico 56% de la muestra, y apenas 43,8% supieron decir correctamente nombres y dosis de los medicamentos. Tenían por lo menos una internación psiqui

  13. Who amends the International Code of Nomenclature for algae, fungi, and plants, the participation that the Latin American Herbaria have and how it can be increased? ¿Quién modifica el Código Internacional de Nomenclatura para algas, hongos y plantas, que participación tienen los herbarios latinoamericanos y como puede ésta incrementarse?

    Directory of Open Access Journals (Sweden)

    Lourdes Rico-Arce

    2012-12-01

    Full Text Available Changes to the International Code of Botanical Nomenclature are decided upon every 6 years at Nomenclature Sections that are part of International Botanical Congresses (IBC. How the Code is amended? The "decision" to conserve the name Acacia with a new type from Australia, one of the most heated and polarized debates over botanical nomenclature, casting doubt over the legitimacy of the procedure and botanical decision-making is taken as example. Despite a website www.acaciavote.com, for which by July 2011, the votes were: 7 659 opposing the re-typification of Acacia, including 101 votes from people in Australia, and only 110 accepting the re-typification, did not make any affect to influence to amend the Code? Only delegates present at the Nomenclature Section and the number of active institutional votes that they carry can decide the changes to the Code; from 878 distributed to registered herbaria only 396 of these were taken to Melbourne. Australia and the United States were the countries with the largest number of votes. There is little participation of Latin American Countries, in general of developing countries, how this can be increased and effective throughout herbaria institutional votes? In this note the steps to follow up are given.Cada 6 años se debate sobre las modificaciones que se efectuarán en el Código Internacional de Nomenclatura en el marco del Congreso Internacional de Botánica. ¿Quién decide modificar el código? Se toma como ejemplo la "decisión" de conservar el nombre del género Acacia con un nuevo tipo de una especie australiana, que es uno de los debates más controversiales y polarizados en la historia de la nomenclatura botánica, a la vez que puso en duda lo legitimidad del procedimiento efectuado. A pesar de los resultados que tuvo el sitio web www.acaciavote.com a fines de Julio del 2011, 7 659 se opusieron a la retipificación, que incluyeron 101 de personas Australiana, en contra de solo 110 aceptando esta

  14. Intermediation in Foreign Trade: When do Exporters Rely on Intermediaries?

    DEFF Research Database (Denmark)

    Schröder, Philipp J.H.; Trabold, H.; Trübswetter, P.

    2005-01-01

    The paper explores the question of why trade intermediaries (TIs) are frequently used as agents for exports to some countries but not to others. First, we adapt a standard intra-industry trade model with variable export costs (e.g. transport) and fixed export costs (e.g. market access) to include...... a TI that is able to pool market access cost. This framework suggests explanatory factors for the TI share in a country's exports, which are largely in line with the literature. Second, we test these explanatory factors with a new data set based on French customs information. The paper finds that: (i......) higher market access costs increase the TI share, (ii) smaller export markets feature a larger TI share, (iii) network effects are important determinants of trade intermediation....

  15. Intermediation in Foreign Trade: When do Exporters Rely on Intermediaries?

    DEFF Research Database (Denmark)

    Schröder, Philipp; Trabold, Harald; Trübswetter, Parvati

    2003-01-01

    The paper explores theoretically and empirically why trade intermediaries (TIs) are frequently used as agents for exports to some countries but not to others. We adapt a standard intra-industry trade model with variable export costs (e.g. transport) and fixed export costs (e.g. market access......) to include a TI that is able to pool market access cost. From this framework explanatory factors for the TI share in a country's exports are derived and subsequently tested with a new data set based on French customs information. The paper finds that: (i) higher market access costs increase the TI share, (ii......) smaller export markets feature a larger TI share, (iii) the TI share is independent from variable (distance-dependent) export costs....

  16. Towards Concept Understanding relying on Conceptualisation in Constructivist Learning

    DEFF Research Database (Denmark)

    Badie, Farshad

    2017-01-01

    and understandings over their mental structures in the framework of constructivism, and I will clarify my logical [and semantic] conceptions of humans’ concept understandings. This research focuses on philosophy of education and on logics of human learning. It connects with the topics ‘Cognition in Education......, through this constructivism to a pedagogical theory of learning. I will mainly focus on conceptual and epistemological analysis of humans’ conceptualisations based on their own mental objects (schemata). Subsequently, I will propose an analytical specification of humans’ conceptualisations...

  17. A Formal Semantics for Concept Understanding relying on Description Logics

    DEFF Research Database (Denmark)

    Badie, Farshad

    2017-01-01

    logical assumptions whose discovery may lead us to a better understanding of ‘concept understanding’. The Structure of Observed Learning Outcomes (SOLO) model as an appropriate model of increasing complexity of humans’ understanding has supported the formal analysis.......In this research, Description Logics (DLs) will be employed for logical description, logical characterisation, logical modelling and ontological description of concept understanding in terminological systems. It’s strongly believed that using a formal descriptive logic could support us in revealing...

  18. Uganda's beef industry has for long relied on indigenous cattle ...

    African Journals Online (AJOL)

    Animal

    growing. The Ministry of Agriculture Animal Industry and Fisheries estimated the exotic/crossbred cattle population at 1.3 million, .... Carcass components. Slaughter weight 248.7 250.2 255.0. 3.8. 220.2c. 257.1b. 276.5a. 4.0 ns. ***. Hot carcass weight. 126.7 129.3 130.8. 2.4. 109.6c. 132.3b. 145.0a. 2.5 ns. ***. Hot carcass ...

  19. A Formal Semantics for Concept Understanding relying on Description Logics

    DEFF Research Database (Denmark)

    Badie, Farshad

    2017-01-01

    In this research, Description Logics (DLs) will be employed for logical description, logical characterisation, logical modelling and ontological description of concept understanding in terminological systems. It’s strongly believed that using a formal descriptive logic could support us in reveali...... logical assumptions whose discovery may lead us to a better understanding of ‘concept understanding’. The Structure of Observed Learning Outcomes (SOLO) model as an appropriate model of increasing complexity of humans’ understanding has supported the formal analysis....

  20. On liberation of communities which relies on nuclear power

    International Nuclear Information System (INIS)

    Park, Seung-Joon

    2013-01-01

    Just after the Nuclear Regulation Authority pointed out possible active faults for fracture zones just under the Tsuruga nuclear power station, local government of reactor site criticized this view was mere judgement of small experts group after its short-term field survey and evaluation meeting without enough discussion with nuclear operators. Behavior of local government, which should insist assurance of residents safety at first, seemed inscrutable and the industrial and financial structure of communities dependent on nuclear power should be clarified. Accident affected costs of nuclear power station estimated in the past were far beyond several trillion yen but local residents of reactor site used to believe accident risk might be negligible because of quite low accident probability estimated by probabilistic safety analysis. Economy of local government of reactor site was dependent on nuclear power. Economic benefits consisted of tax or subsidy income of local governments (financial aspect) and limited employment or grants of residents (economical aspect). Depreciation of relevant nuclear power station varied financial dependency of local government respectively, which could be compensated by local tax subsidy after nuclear power was abolished. Local industry dependent on nuclear power was mostly subcontracted building work or related service industry. Nuclear power phaseout could bring about new employment of residents at reactor site with decommissioning works and introduction of gas-fired thermal power or production center for renewable energy. (T. Tanaka)

  1. CASE STUDY: The Philippines — Progress relies on sound ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-17

    Dec 17, 2010 ... Today, Pasay suffers from overcrowding, unemployment, and ... Ensure environmental sustainability; Develop a global partnership for development. ... in partnership with the business sector, decided to organize job fairs in ...

  2. Mosquitoes rely on their gut microbiota for development

    Science.gov (United States)

    Coon, Kerri L.; Vogel, Kevin J.; Brown, Mark R.; Strand, Michael R.

    2014-01-01

    Field studies indicate adult mosquitoes (Culicidae) host low diversity communities of bacteria that vary greatly among individuals and species. In contrast, it remains unclear how adult mosquitoes acquire their microbiome, what influences community structure, and whether the microbiome is important for survival. Here we used pyrosequencing of 16S rRNA to characterize the bacterial communities of three mosquito species reared under identical conditions. Two of these species, Aedes aegypti and Anopheles gambiae, are anautogenous and must blood feed to produce eggs, while one, Georgecraigius atropalpus, is autogenous and produces eggs without blood feeding. Each mosquito species contained a low diversity community comprised primarily of aerobic bacteria acquired primarily from the aquatic habitat in which larvae developed. Our results suggested the communities in Ae. aegypti and An. gambiae larvae share more similarities with one another than with Ge. atropalpus. Studies with Ae. aegypti also strongly suggested that adults transstadially acquired several members of the larval bacterial community, but only four genera of bacteria present in blood fed females were detected on eggs. Functional assays showed that axenic larvae of each species failed to develop beyond the first instar. Experiments with Ae. aegypti indicated several members of the microbial community and Escherichia coli successfully colonized axenic larvae and rescued development. Overall, our results provide new insights about the acquisition and structure of bacterial communities in mosquitoes. They also indicate three mosquito species spanning the breadth of the Culicidae depend on their gut microbiome for development. PMID:24766707

  3. Organization of Circadian Behavior Relies on Glycinergic Transmission.

    Science.gov (United States)

    Frenkel, Lia; Muraro, Nara I; Beltrán González, Andrea N; Marcora, María S; Bernabó, Guillermo; Hermann-Luibl, Christiane; Romero, Juan I; Helfrich-Förster, Charlotte; Castaño, Eduardo M; Marino-Busjle, Cristina; Calvo, Daniel J; Ceriani, M Fernanda

    2017-04-04

    The small ventral lateral neurons (sLNvs) constitute a central circadian pacemaker in the Drosophila brain. They organize daily locomotor activity, partly through the release of the neuropeptide pigment-dispersing factor (PDF), coordinating the action of the remaining clusters required for network synchronization. Despite extensive efforts, the basic principles underlying communication among circadian clusters remain obscure. We identified classical neurotransmitters released by sLNvs through disruption of specific transporters. Adult-specific RNAi-mediated downregulation of the glycine transporter or impairment of glycine synthesis in LNv neurons increased period length by nearly an hour without affecting rhythmicity of locomotor activity. Electrophysiological recordings showed that glycine reduces spiking frequency in circadian neurons. Interestingly, downregulation of glycine receptor subunits in specific sLNv targets impaired rhythmicity, revealing involvement of glycine in information processing within the network. These data identify glycinergic inhibition of specific targets as a cue that contributes to the synchronization of the circadian network. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Radiological services pact relies on teamwork and experience [dose management

    International Nuclear Information System (INIS)

    Cruden, D.S.

    1988-01-01

    Virginia Power has entered into a radiological service agreement with Westinghouse. The contract commits Westinghouse to work in partnership with Virginia Power to improve performance in the areas of radiological protection, decontamination, ALARA, and radioactive waste management. It is expected that the agreement will solve the problems caused by the shortage of qualified contractor personnel during scheduled outages. (U.K.)

  5. Supercontinuum generation in silicon waveguides relying on wave-breaking.

    Science.gov (United States)

    Castelló-Lurbe, David; Silvestre, Enrique

    2015-10-05

    Four-wave-mixing processes enabled during optical wave-breaking (OWB) are exploited in this paper for supercontinuum generation. Unlike conventional approaches based on OWB, phase-matching is achieved here for these nonlinear interactions, and, consequently, new frequency production becomes more efficient. We take advantage of this kind of pulse propagation to obtain numerically a coherent octave-spanning mid-infrared supercontinuum generation in a silicon waveguide pumping at telecom wavelengths in the normal dispersion regime. This scheme shows a feasible path to overcome limits imposed by two-photon absorption on spectral broadening in silicon waveguides.

  6. Fast uncertainty reduction strategies relying on Gaussian process models

    International Nuclear Information System (INIS)

    Chevalier, Clement

    2013-01-01

    This work deals with sequential and batch-sequential evaluation strategies of real-valued functions under limited evaluation budget, using Gaussian process models. Optimal Stepwise Uncertainty Reduction (SUR) strategies are investigated for two different problems, motivated by real test cases in nuclear safety. First we consider the problem of identifying the excursion set above a given threshold T of a real-valued function f. Then we study the question of finding the set of 'safe controlled configurations', i.e. the set of controlled inputs where the function remains below T, whatever the value of some others non-controlled inputs. New SUR strategies are presented, together with efficient procedures and formulas to compute and use them in real world applications. The use of fast formulas to recalculate quickly the posterior mean or covariance function of a Gaussian process (referred to as the 'kriging update formulas') does not only provide substantial computational savings. It is also one of the key tools to derive closed form formulas enabling a practical use of computationally-intensive sampling strategies. A contribution in batch-sequential optimization (with the multi-points Expected Improvement) is also presented. (author)

  7. Pantomimes are special gestures which rely on working memory.

    Science.gov (United States)

    Bartolo, A; Cubelli, R; Della Sala, S; Drei, S

    2003-12-01

    The case of a patient is reported who presented consistently with overt deficits in producing pantomimes in the absence of any other deficits in producing meaningful gestures. This pattern of spared and impaired abilities is difficult to reconcile with the current layout of cognitive models for praxis. This patient also showed clear impairment in a dual-task paradigm, a test taxing the co-ordination aspect of working memory, though performed normally in a series of other neuropsychological measures assessing language, visuo-spatial functions, reasoning function, and executive function. A specific working memory impairment associated with a deficit of pantomiming in the absence of any other disorders in the production of meaningful gestures suggested a way to modify the model to account for the data. Pantomimes are a particular category of gestures, meaningful, yet novel. We posit that by their very nature they call for the intervention of a mechanism to integrate and synthesise perceptual inputs together with information made available from the action semantics (knowledge about objects and functions) and the output lexicon (stored procedural programmes). This processing stage conceived as a temporary workspace where gesture information is actively manipulated, would generate new motor programmes to carry out pantomimes. The model of gesture production is refined to include this workspace.

  8. Detection of pressure tube leaks relying on moisture beetles only

    International Nuclear Information System (INIS)

    Kenchington, J.M.; Choi, A.; Jin, Y.

    2004-01-01

    A major decision was made for Pickering NGS A Annulus Gas System (ACS) that detection of a pressure tube (PT) leak should be achieved by using only moisture beetles and that dew point monitors would provide 'early warning' without status to shut down the reactor. Experience with Unit 3 has shown that dew point monitoring of pressure tube leaks was particularly subject to gas leaks and surface adsorption effects. Unit 4 was the first one to be converted during the full scale pressure tube replacement programme. Because of the fundamental change in design philosophy, moisture injection tests were carried out during commissioning to demonstrate that performance matched design. In particular it was necessary to show that leak before break (LBB) would be achieved if a leak occurred in the limiting string. Units 1 and 3 have since been converted. No decision has been taken to convert Pickering B units as gas leaks are small and no significant adsorption effects are anticipated. Hence dew point monitoring will not be impaired. (author)

  9. Unlocking good design does not rely on designers alone

    DEFF Research Database (Denmark)

    Rodil, Kasper; Eskildsen, Søren; Morrison, Ann

    This article describes on-going research in the design of sustainable systems to support transfer of indigenous knowledge between rural elders and city living youths in Namibia. Specifically we here address the importance of co-design and highlight some of our findings through experiences gathere...

  10. Hepatitis C virus relies on lipoproteins for its life cycle.

    Science.gov (United States)

    Grassi, Germana; Di Caprio, Giorgia; Fimia, Gian Maria; Ippolito, Giuseppe; Tripodi, Marco; Alonzi, Tonino

    2016-02-14

    Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma. Viral persistence and pathogenesis are due to the ability of HCV to deregulate specific host processes, mainly lipid metabolism and innate immunity. In particular, HCV exploits the lipoprotein machineries for almost all steps of its life cycle. The aim of this review is to summarize current knowledge concerning the interplay between HCV and lipoprotein metabolism. We discuss the role played by members of lipoproteins in HCV entry, replication and virion production.

  11. Why cryptography should not rely on physical attack complexity

    CERN Document Server

    Krämer, Juliane

    2015-01-01

    This book presents two practical physical attacks. It shows how attackers can reveal the secret key of symmetric as well as asymmetric cryptographic algorithms based on these attacks, and presents countermeasures on the software and the hardware level that can help to prevent them in the future. Though their theory has been known for several years now, since neither attack has yet been successfully implemented in practice, they have generally not been considered a serious threat. In short, their physical attack complexity has been overestimated and the implied security threat has been underestimated. First, the book introduces the photonic side channel, which offers not only temporal resolution, but also the highest possible spatial resolution. Due to the high cost of its initial implementation, it has not been taken seriously. The work shows both simple and differential photonic side channel analyses. Then, it presents a fault attack against pairing-based cryptography. Due to the need for at least two indepe...

  12. Rapid Fear Detection Relies on High Spatial Frequencies

    NARCIS (Netherlands)

    Stein, T.; Seymour, K.; Hebart, M.N.; Sterzer, P.

    Signals of threat—such as fearful faces—are processed with priority and have privileged access to awareness. This fear advantage is commonly believed to engage a specialized subcortical pathway to the amygdala that bypasses visual cortex and processes predominantly low-spatial-frequency information

  13. Progress relies on sound information in the Philippines

    International Development Research Centre (IDRC) Digital Library (Canada)

    numerous out-of-school youth is based on HOPES — HIV prevention ... Loved, cared for and protected, Educated and empowered,. Savings ... provided the foundation for these and other programs. Carried out .... Promote gender equality.

  14. Working memory for conjunctions relies on the medial temporal lobe.

    Science.gov (United States)

    Olson, Ingrid R; Page, Katie; Moore, Katherine Sledge; Chatterjee, Anjan; Verfaellie, Mieke

    2006-04-26

    A prominent theory of hippocampal function proposes that the hippocampus is importantly involved in relating or binding together separate pieces of information to form an episodic representation. This hypothesis has only been applied to studies of long-term memory because the paradigmatic view of the hippocampus is that it is not critical for short-term forms of memory. However, relational processing is important in many working memory tasks, especially tasks using visual stimuli. Here, we test the hypothesis that the medial temporal lobes are important for relational memory even over short delays. The task required patients with medial temporal lobe amnesia and controls to remember three objects, locations, or object-location conjunctions over 1 or 8 s delays. The results show that working memory for objects and locations was at normal levels, but that memory for conjunctions was severely impaired at 8 s delays. Additional analyses suggest that the hippocampus per se is critical for accurate conjunction working memory. We propose that the hippocampus is critically involved in memory for conjunctions at both short and long delays.

  15. ¿Quién decide? ¿Quién es responsable? ¿Quién gana? Análisis de las dificultades para la implantación de equipos de trabajo

    Directory of Open Access Journals (Sweden)

    AITOR ARITZETA

    2006-01-01

    Full Text Available En la literatura de gestión y de la Psicología del Trabajo y de las Organizaciones existe una sobreabundancia de testimonios referidos a la influencia positiva de los equipos de trabajo sobre variables psicosociales y sobre los resultados económicos de las empresas donde se implantan. Sin embargo, sospechamos que tal sobre representación de éxitos no siempre refleja la realidad de las empresas. Este trabajo pretende realizar un análisis de las dificultades que la implantación de equipos de trabajo conlleva en los procesos de reestructuración del poder y de la organización del trabajo. También se examinarán algunas de las resistencias de carácter individual que suelen aparecer al iniciar procesos de reestructuración organizacional en base a equipos de trabajo. Este artículo no pone en duda la potencialidad de los equipos de trabajo, lo que cuestiona es que puedan llegar a ser efectivos sin una adecuada dirección, estructura, formación y facilitación. Desarrollando una apreciación más crítica de los costes y beneficios de la implantación de sistemas de trabajo basados en equipos esperamos favorecer un uso más apropiado de los mismos.

  16. La répartition géographique des poissons d'eau douce en France : qui est autochtone et qui ne l'est pas ?

    Directory of Open Access Journals (Sweden)

    PERSAT H.

    1997-01-01

    Full Text Available Les bouleversements intervenus ces dernières décennies dans la composition de l'ichtyofaune d'eau douce française incitent, d'une part, à faire un bilan de la situation présente (cf. l'Atlas des poissons d'eau douce de France et, d'autre part, à promouvoir une politique de gestion cohérente avec le principe de protection du patrimoine biologique naturel. Cette notion de patrimoine reste toutefois à définir. En effet, les changements actuels ne sont que les derniers d'une longue série, où l'homme est un acteur capital depuis plus longtemps qu'on ne le croit. De fait, beaucoup des espèces dites françaises n'ont probablement pas de valeur patrimoniale dans nombre de nos bassins fluviaux. Le présent article a pour ambition de décrire l'ampleur du problème et de solliciter la communauté scientifique, afin de rassembler les informations et développer les investigations selon un cadre géographique et historique précis.

  17. Las preguntas por la calidad de la vivienda: ¿quién las hace?, ¿quién las responde?

    Directory of Open Access Journals (Sweden)

    Clemencia Escallón

    2010-07-01

    Full Text Available Este artículo presenta las distintas estrategias que ha buscado el Grupo de Investigación en Gestión y Diseño de Vivienda (GIV, del Departamento de Arquitectura de la Universidad de los Andes, para comprender y evidenciar el problema percibido sobre la calidad de la vivienda, particularmente de los sectores más pobres de la población colombiana. El enfoque se hace desde el ámbito académico con el Laboratorio de Vivienda y desde el escenario de la relación universidad-empresa según convenio de asociación con Prodesa S. A. La alerta se inicia con la preocupación por la condición de la vivienda de interés social (VIS en Bogotá: lotes estrechos, viviendas pequeñas con ubicación urbana de extrema periferia, para ir complejizando la mirada a través de preguntas como: ¿Qué facilidades urbanas tiene la ciudad en la que se construye la VIS? ¿Qué tipo de urbanizaciones o agrupaciones se están proponiendo? ¿Cuál es la espacialidad de la vivienda que se ofrece? Interesa explorar si es factible medir la calidad de la vivienda VIS, y si lo es, con qué indicadores y valoraciones se debe hacer. El artículo expone las razones de esta búsqueda, los instrumentos técnicos planteados para acercarse a las respuestas, y el análisis de los resultados y retos de la que hemos llamado “primera fase de observación”.

  18. ¿Quién es quién? La descripción física en el aula de E/LE

    Directory of Open Access Journals (Sweden)

    Vicente Moratal Canales

    2011-01-01

    Full Text Available Esta experiencia pretende aportar una posibilidad más para lograr la cohesión y la participación en un aula de español para inmigrantes donde, para salvar la heterogeneidad, se convierte en necesario conseguir la participación activa de los estudiantes.Para tal objetivo se propone realizar una actividad en la que los estudiantes trabajen la descripción desde un enfoque comunicativo, dejando de lado la expresión escrita.

  19. ¿Quién es quién? La descripción física en el aula de E/LE (tarjetas

    Directory of Open Access Journals (Sweden)

    Vicente Moratal Canales

    2012-08-01

    Full Text Available Esta experiencia pretende aportar una posibilidad más para lograr la cohesión y la participación en un aula de español para inmigrantes donde, para salvar la heterogeneidad, se convierte en necesario conseguir la participación activa de los estudiantes.Para tal objetivo se propone realizar una actividad en la que los estudiantes trabajen la descripción desde un enfoque comunicativo, dejando de lado la expresión escrita.

  20. ¿Quién es quién? La descripción física en el aula de E/LE (Powerpoint

    Directory of Open Access Journals (Sweden)

    Vicente Moratal Canales

    2012-08-01

    Full Text Available Esta experiencia pretende aportar una posibilidad más para lograr la cohesión y la participación en un aula de español para inmigrantes donde, para salvar la heterogeneidad, se convierte en necesario conseguir la participación activa de los estudiantes.Para tal objetivo se propone realizar una actividad en la que los estudiantes trabajen la descripción desde un enfoque comunicativo, dejando de lado la expresión escrita.

  1. ¿Quién es quién? La descripción física en el aula de E/LE (Powerpoint2

    Directory of Open Access Journals (Sweden)

    Vicente Moratal Canales

    2012-08-01

    Full Text Available Esta experiencia pretende aportar una posibilidad más para lograr la cohesión y la participación en un aula de español para inmigrantes donde, para salvar la heterogeneidad, se convierte en necesario conseguir la participación activa de los estudiantes.Para tal objetivo se propone realizar una actividad en la que los estudiantes trabajen la descripción desde un enfoque comunicativo, dejando de lado la expresión escrita.

  2. Comment protéger la santé des travailleurs dans un système qui ne repose pas sur les notions d’aptitude et d’inaptitude ? How to protect workers’ health in a system that is not based on the concepts of “capacity” and “incapacity” Cómo proteger la salud de los trabajadores en un sistema que no se basa en los conceptos de aptitud et ineptitud ?

    Directory of Open Access Journals (Sweden)

    Robert Plante

    2010-02-01

    Full Text Available Au Québec, en santé au travail, l’approche de santé publique a été privilégiée à l’approche médicale individuelle, parce qu’elle est conséquente aux objectifs de la loi, à savoir la prise en charge par le milieu de ses problèmes et la diminution, voire l’élimination des dangers. Quant aux activités médicales individuelles, elles ne sont réalisées que lorsqu’elles sont légitimes, c’est-à-dire lorsque leur pertinence et leur efficacité sur le plan de la prévention ont été démontrées. Quelques évaluations l’ont confirmé, l’approche par programme des services de santé publique québécois fonctionne en général très bien et elle est efficace. Mieux que l’examen médical de chaque sujet, elle permet de centrer les énergies sur les expositions professionnelles et les composantes de l’organisation du travail susceptibles de provoquer des problèmes. Malgré toutes ses qualités, le système de santé au travail québécois se heurte à de sérieuses résistances institutionnelles et politiques qui ont compromis son développement et mènent progressivement à son essoufflement.In Québec, in occupational health, the public health approach has been favoured over the individual medical approach because it is consistent with the objectives of the law, namely this community taking charge of its problems, and the reduction and even elimination of risk factors. Individual medical activities are limited to cases where the relevance and effectiveness of preventive benefits have been demonstrated. Some evaluative studies have shown that this Québec public health program approach works well in general, and is effective. Compared with the medical examination of each subject, it has a better potential for focusing energies on occupational exposures and on work organizational factors that could cause problems. Despite all its advantages, the Québec occupational health system is facing serious institutional and

  3. Okuma Gelişiminde Üst Dil Farkındalığı, Sesbilgisel Süreçler ve Bellek Süreçlerinin Etkisi: Kısa Süreli Bellek ve Çalışma Belleği

    Directory of Open Access Journals (Sweden)

    Filiz Sayar

    2012-07-01

    Full Text Available Bu makalede, alanyazında okuma gelişimini belirleyen üstdil farkındalığı, sesbilgisel beceriler ile bellek işlevlerine yer veren araştırmalar incelenmiştir. Bu bilişsel süreçler, karmaşık bir süreç olan okuma gelişimini farklı şekilde etkilemektedir. Bu makalede ele alınan araştırmalarda, başarılı bir okuma performansı için üstdil farkındalığının gerekli olduğu sonucuna ulaşılırken; üstdil farkındalığı becerilerinden sesbilgisel farkındalığın okumanın en güçlü yordayıcısı olduğu konusunda fikirbirliği sağlanmıştır. Okuma gelişimi ile kısa-süreli bellek ve çalışma belleği ilişkisini inceleyen araştırmalar ise, çalışma belleğinin kısa-süreli belleğe göre okumada daha etkili olduğu yönünde bulgular elde etmişlerdir. Diğer yandan, okuma gelişimi konusunda çalışmalarını yürüten bazı araştırmacılar, okumanın çok yönlü ve çoklu-etkenli olması nedeniyle okuma gelişimini belirleyecek tek ve en güçlü bilişsel etmenin bulunamayacağını ifade etmişlerdir. The research in the literature dealing with metalinguistic awareness, phonological abilities and memory functions determinig reading development were examined in this article. These cognitive processes determine differently reading that is a complicated process. The research stated in this article suggested that metalinguistic awareness was crucial for successful reading performance and agreed that phonological awareness one of the metalinguistic abilities was the most powerful predictor of reading. The research examining short-term memory and working memory with reading development obtained some evidence that working memory was more influential on reading than short-term memory. On the other hand, some researchers searching on reading development stated that unique and the most powerful cognitive factor predicting reading development could not be found because reading was multidirectional and

  4. Tout ce qui brille n’est point or / Nem tudo que brilha é ouro

    Directory of Open Access Journals (Sweden)

    Nathalie Moureau

    2017-10-01

    Full Text Available O preço de uma obra corresponde ao seu valor artístico? A economista Nathalie Moureau mostra que valor econômico e valor artístico da obra contemporânea são geralmente desconectados, dando lugar à aparição de bolhas especulativas. Três fatores principais explicam, assim, essa defasagem: a informação mediática, a pesquisa de distinção, a especulação. RESUME: Le prix d’une œuvre correspond-il à sa valeur artistique ? L’économiste Nathalie Moureau montre que valeur économique et valeur artistique de l’œuvre contemporaine sont généralement déconnectées, donnant lieu à l’apparition de bulles spéculatives. Trois facteurs principaux expliquent alors ce décalage: l’information médiatique, la recherche de distinction, la spéculation. MOTS CLE: l’information médiatique, la recherche de distinction, la spéculation ABSTRACT: Does the price of a work correspond to its artistic value? Economist Nathalie Moureau shows that the economic value and artistic value of contemporary art are often disconnected, giving rise to the appearance of speculative bubbles. Three main factors explain, therefore, this lag: media information, research of distinction, speculation. KEYWORDS: media information, research of distinction, speculation.

  5. Por quién los ríos secan?

    Directory of Open Access Journals (Sweden)

    Anália M. M. C. Amorim

    2015-06-01

    Full Text Available This paper analyzes the distribution of population in Brazil, one of the starting points for understanding the formation of cities and enduring social inequality. Its goal is to describe and to reflect about the decisions of architectural planning, territory design, and urban planning, and to propose a possible course correction. Two scenarios served as its backdrop: the state of violence and misery to which poor people are subjected in Brazilian urban centers and how one faces the water issues in Brazil, especially in its Northeast Region. At its core, this paper questions the vector mode for planning growth in a territory and analyzes two points: the behavior of populations and the knowledge of the waters. It starts out from the statement that the Brazilian Northeast exports two products: man and water. It also provides a brief analysis about a project to divert part of the São Francisco River to fight the desertification process in the Brazilian semi-arid region and discusses a national alternative to face this problem.

  6. Les femmes, un effectif sur qui il faut compter | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    30 juil. 2015 ... L'emploi peut transformer la vie d'une personne et une société tout entière. ... leur revenu potentiel et améliorer la distribution des ressources dans les familles. ... où les salaires sont faibles et les protections sociales minimes.

  7. El Mercosur agrario: ¿Integración para quién?

    Directory of Open Access Journals (Sweden)

    Agostina Costantino

    2010-09-01

    Full Text Available Se estudian en este trabajo los efectos sobre la estructura agraria de la formación del Mercado Común del Sur (Mercosur. Este proceso de integración regional fue guiado por la perspectiva política del realismo periférico y dentro de un marco de regionalismo abierto, lo que consagró la apertura comercial como el aspecto más desarrollado del nuevo bloque. Este proceso tendió a favorecer a los grandes capitales. En el agro, en cambio, la agricultura familiar empezó a ser desplazar y a reforzarse un modelo concentrador y latifundista caracterizado por los monocultivos orientados a la exportación, organizado sobre relaciones capitalistas de producción.AbstractIn this work, we study the effect of the formation of the Southern Common Market (Mercosur on the agrarian structure. This process of regional integration was guided by the peripheral realism political perspective and within the framework of open regionalism which consecrated open markets as the most developed aspect of the new block. This process tended to favor large capital. In the countryside, on the other hand, family farms began to be displaced and the large landholding model to be reinforced, characterized by monocultures oriented to export, a model organized according to capitalist production relations.

  8. La formación de profesionales empresarios. ¿Responsabilidad de quién?

    Directory of Open Access Journals (Sweden)

    Jairo Enrique Rodríguez Hernández

    2015-04-01

    Full Text Available RESUMEN Esta es una pregunta que muy a menudo se formulan, educadores, empresarios, políticos, profesionales, gobierno y universitarios. Igualmente, se discute el papel de la universidad, como ente determinante en la calificación y profesionalización del Recurso Humano. Su quehacer en el campo de la investigación,  su liderazgo en el tratamiento de los grandes conflictos nacionales, su papel en el manejo de las organizaciones  empresariales, etc. Tradicionalmente, la universidad encaminó su acción hacia la formación de profesionales con capacidad de enfrentar los retos del mundo productivo, como empleados. Sin embargo, en los últimos 20 años el modelo cambió. Hoy la sociedad espera empresarios que generen su propio  negocio y contribuyan al fomento de nuevos empleos.

  9. Número Pregunta Respuesta 1 1. ¿Quién es la entidad responsable ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Carlos Guiza

    En el punto 5.1 de la página 8, se indica que "se espera que la institución ejecutora contribuya con recursos de contrapartida con el fin de complementar las necesidades establecidas en el plan de proyecto a ser presentado y acordado con SCALA”. Los recursos de contrapartida no están incluidos en los $700.000.

  10. ¿Quiénes fueron y qué hacen nuestros primeros profesionales?

    Directory of Open Access Journals (Sweden)

    María Velásquez Moreno

    2011-12-01

    Full Text Available Formar profesionales en la Administración de empresas y Economía, fue un reto para la educación de aquellos tiempos. La Facultad  de Ciencias Administrativas y Económicas, fue creada  con  profunda visión de aportar en  áreas   del conocimiento   científico,   económico, administrativo,   financieros,   dinamizador   de   la producción de bienes y servicios   a través de funciones gerenciales, en haras de cubrir las expectativas del pais que ya proyectaba cambio   de época;  desarrollar proyectos, planes y estructuras en su organización,  que permita   el   crecimiento   sostenido   del profesional graduado ha sido una meta cumplida, razón que permite demostrar a través de este articulo investigativo, donde están laborando y quienes fueron   los primeros frutos graduados en este templo del conocimiento.

  11. Une ONG béninoise opère des changements organisationnels qui l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    28 avr. 2016 ... Mapping sexual harassment in Egypt. More than 95 per cent of women in Egypt have experienced sexual harassment at least once, but many citizens there turn a blind eye when it happens. View moreMapping sexual harassment in Egypt ...

  12. Sécurité alimentaire et nutrition : des innovations qui aident les plus ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    28 oct. 2010 ... Le CRDI contribue à accroître la sécurité alimentaire et à améliorer la valeur nutritive des aliments depuis qu'il a vu le jour en 1970. Les recherches menées en vue de trouver des moyens de nourrier les populations pauvres ont permis de mettre au point des variétés végétales améliorées, d'accroître ...

  13. Régler le cas des rejets miniers qui polluent l'environnement | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    sensibiliser les gouvernements, l'industrie et les citoyens aux effets néfastes des rejets miniers sur l'environnement et sur la santé des collectivités locales;; mettre au point des méthodes efficaces pour lutter contre la pollution engendrée par les rejets miniers; établir des techniques de remise en état des sites d'exploitation ...

  14. pour le trimestre qui a pris fin le 31 décembre 2012

    International Development Research Centre (IDRC) Digital Library (Canada)

    acray

    31 déc. 2012 ... -24,8 %. Contributions de bailleurs de fonds. Financement de la programmation en recherche pour le développement. 39 837. 11 122. 9 044. 11 376. -20,5 %. 29 081. 25 399. 25 400. 0,0 % ..... internationales d'information financière (normes IFRS) telles que publiées par le Conseil des normes comptables ...

  15. pour le trimestre qui a pris fin le 30 juin 2014

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    30 juin 2014 ... ÉTATS FINANCIERS INTERMÉDIAIRES RÉSUMÉS, NON AUDITÉS. 9. Déclaration de responsabilité de la direction. 11 État intermédiaire résumé de la situation ... d'information financière (normes IFRS). ..... Le total des passifs a diminué de 4,4 millions de dollars (ou 7,9 %) par rapport à ce qu'il était.

  16. pour le trimestre qui a pris fin le 30 juin 2012

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    30 juin 2012 ... 7. Déclaration de responsabilité de la direction. 8. État de la situation financière. 9. État du résultat global. 10. État des variations des capitaux propres. 11 ... avec les états financiers non audités (à la page 9). ..... et à toutes les autres normes internationales d'information financière (normes IFRS) telles que.

  17. pour le trimestre qui a pris fin le 30 septembre 2012

    International Development Research Centre (IDRC) Digital Library (Canada)

    acray

    30 sept. 2012 ... recommande de lire ce rapport en parallèle avec les états financiers non audités (à la page 9). L'information et les .... développement ont augmenté de 56,9 % par rapport au même trimestre de l'exercice 2011-2012 ..... IFRS) telles que publiées par le Conseil des normes comptables internationales (CNCI).

  18. pour le trimestre qui a pris fin le 31 décembre 2013

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    31 déc. 2013 ... IFRS 9 – Instruments financiers. Le CNCI a l'intention de remplacer la norme IAS 39 – Instruments financiers : comptabilisation et évaluation par la norme IFRS 9. La nouvelle norme guide la classification, la comptabilisation, la décomptabilisation et l'évaluation des actifs et des passifs financiers. Le Centre ...

  19. pour le trimestre qui a pris fin le 30 septembre 2013

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    30 sept. 2013 ... 9. Perspectives. ÉTATS FINANCIERS INTERMÉDIAIRES RÉSUMÉS, NON AUDITÉS. 11 Déclaration de responsabilité de la direction. 13 État intermédiaire résumé de la situation financière ... d'information financière (normes IFRS). Toutes les sommes sont exprimées en dollars canadiens, à moins ...

  20. La molécule qui sauvera les mangues | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    29 juin 2017 ... Scène de nuit dans un marché de gros à Krishnagiri où sont vendues des ... du Fonds canadien de recherche sur la sécurité alimentaire internationale. .... de Coimbatore où l'on explore d'autres modes d'emploi de l'hexanal, dont la ... Droits d'auteur · Éthique de la recherche · Politique de libre accès ...

  1. Dependencia versus autodeterminación: Una ley para quién

    OpenAIRE

    Fernández, Pedro

    2006-01-01

    El autor de este artículo, director de la Federación de asociaciones a favor de las personas con discapacidad intelectual del País Vasco, analiza el contenido que, en la fase de redacción correspondiente a octubre de 2006, caracteriza al proyecto de Ley de Dependencia. Aunque muestra su confianza por que al final se reconocerán en la Ley las necesidades de apoyo para la autonomía personal que requieren las personas con discapacidad intelectual o mental para hacer efectivo un grado satisfactor...

  2. Document on the climate evolutions; Dossier climat ce qui va changer

    Energy Technology Data Exchange (ETDEWEB)

    Deque, M. [Meteo France 75 - Paris (France); Baruch, J.O.; Theodule, M.L.; Kingler, C.; Thivent, V.; Postel-Vinay, O. [La Recherche, 75 - Paris (France); Leblois, E. [Cemagref, 69 - Lyon (France); Gascard, J.C. [Centre National de la Recherche Scientifique (CNRS), 75 - Paris (France); Quadfasel, D. [Hambourg Univ., Institut d' Oceanographie (Germany)

    2006-07-15

    What will be the climate in 2050? From specialists, 2050 is the date of the first signs of the climatic change consequences. In France the daily life will not be very modified, but some activities which depend on the hydrology, will have to adapt. The vegetation modifications, will be little in some areas. Elsewhere, they would be radical: no more arctic ice field in summer, some island flooded by the sea. The authors show also the human activities which will be favored by the climatic change. (A.L.B.)

  3. Brazilian Federal Police drug chemical profiling - the PeQui project.

    Science.gov (United States)

    Zacca, Jorge J; Botelho, Elvio Dias; Vieira, Maurício L; Almeida, Fernanda L A; Ferreira, Luciana S; Maldaner, Adriano O

    2014-07-01

    Over the past six years the Brazilian Federal Police has undertaken major efforts in order to implement and to develop its own drug chemical profiling program. This paper aims to provide a broad perspective regarding the managerial strategies and some examples of subsequent technical issues involved in the implementation of such a project. Close collaboration with local drug enforcement and investigation teams, establishment of proper worldwide partnerships with well recognized institutions in the field of drug analysis and the attainment of suitable funding and human resources are shown to be key success factors. Some preliminary results concerning the chemical profile of cocaine seizures in Brazil during this process are presented. Copyright © 2014 Forensic Science Society. Published by Elsevier Ireland Ltd. All rights reserved.

  4. Recognition Organisations That Evaluate Agencies Accrediting Medical Education Programmes: "Quis Custodiet Ipsos Custodes?"

    Science.gov (United States)

    van Zanten, Marta

    2017-01-01

    The goals of agencies that accredit medical education programmes or institutions are to ensure high quality student experiences and to certify the readiness of graduates to further their training or begin practice as physicians. While accreditation provides a level of legitimacy, the agencies conducting the reviews vary in their organisation,…

  5. Un labo qui défie les lois de la physique

    CERN Multimedia

    Demarthon, Fabrice

    2006-01-01

    Preparation for action! The discoveries about particles don't stop to push aside theories of classic physics. Among the responsibles, a troop of physicists from LAL who track, measure and try to understand the world of infinitely small and the physics of tomorrow. (2 pages)

  6. Web révolution; il y a 17 ans, qui le connaissait?

    CERN Multimedia

    2007-01-01

    When tim Berners Lee, a CERN scientist, found the World Wide Web in 1989, the aim was to find an automatic sharing of the information for scientists working in the universities or institutes in the whole world. (2 pages)

  7. pour le trimestre qui a pris fin le 30 septembre 2016

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    30 sept. 2016 ... Le CRDI finance des travaux de recherche appliquée ... internationales dʼinformation financière (normes IFRS). ..... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en vue du .... Les accords expirent à des dates différentes, et le dernier prend fin en.

  8. Rapport financier trimestriel pour le trimestre qui a pris fin le 31

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    31 déc. 2015 ... Le CRDI finance des travaux de recherche appliquée ... recherches pour le développement international (CRDI, le Centre) et ..... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en .... Les accords expirent à des dates différentes, et le dernier prend fin.

  9. Rapport financier trimestriel pour le trimestre qui a pris fin le 30 juin

    International Development Research Centre (IDRC) Digital Library (Canada)

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    30 juin 2016 ... Le CRDI finance des travaux de recherche appliquée ... développement international (le Centre) et lʼévolution de la ..... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en vue .... Les accords expirent à des dates différentes, et le dernier prend fin en.

  10. pour le trimestre qui a pris fin le 30 juin 2015

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    30 juin 2015 ... Le CRDI finance des travaux de recherche appliquée ... recherches pour le développement international (le Centre) et de ..... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en .... Les accords expirent à des dates différentes, et le dernier prend fin en.

  11. pour le trimestre qui a pris fin le 31 décembre 2014

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    31 déc. 2014 ... Le CRDI finance des travaux de recherche appliquée ... recherches pour le développement international (le Centre) et de ...... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en vue .... Les accords expirent à des dates différentes, et le dernier prend fin.

  12. Rapport financier trimestriel pour le trimestre qui a pris fin le 30

    International Development Research Centre (IDRC) Digital Library (Canada)

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    30 sept. 2015 ... Le CRDI finance des travaux de recherche appliquée ... recherches pour le développement international (le Centre) et de ..... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en .... Les accords expirent à des dates différentes, et le dernier prend fin en.

  13. Rapport financier trimestriel pour le trimestre qui a pris fin le 31

    International Development Research Centre (IDRC) Digital Library (Canada)

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    31 déc. 2016 ... Le CRDI finance des travaux de recherche appliquée ... développement international (le Centre) et lʼévolution de la ...... voie de développement et sur la mise en oeuvre des connaissances scientifiques, techniques et autres en vue du .... vertu d'accords de contribution conclus avec des bailleurs de fonds.

  14. La cage qui cache : La Cage Dorée de Ruben Alves

    Directory of Open Access Journals (Sweden)

    Cristina Marinho

    2015-01-01

    Full Text Available The French Comedy La Cage Dorée (produced by the luso descendant Ruben Alves, 2013 success seems to be mainly due to its clichés of Portuguese epics in Paris, and its miseries may not have been underlined enough. Thus, under this apparently naif portrait an intriguing painting of Portuguese immigrants’ French dis-integration may really be hiding, which is the aim of this essay, on one hand, to bring out and, on the other one, to clarify, by questioning comparative critical common denominators of the two countries.

  15. La cage qui cache : La Cage Dorée de Ruben Alves

    Directory of Open Access Journals (Sweden)

    Cristina Marinho

    2015-12-01

    Full Text Available The French Comedy La Cage Dorée (produced by the luso descendant Ruben Alves, 2013 success seems to be mainly due to its clichés of Portuguese epics in Paris, and its miseries may not have been underlined enough. Thus, under this apparently naif portrait an intriguing painting of Portuguese immigrants’ French dis-integration may really be hiding, which is the aim of this essay, on one hand, to bring out and, on the other one, to clarify, by questioning comparative critical common denominators of the two countries.

  16. Matters which shorten the ozone layer; Substances qui appauvrissent la couche d'ozone

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-12-01

    This document, proposed by the ministry of the national development and the environment, gives the list of the main texts relative to the matters which shorten the ozone layer and the evolution of the community regulations in this domain. The concerned matters are the Cfc and the HCFC production and use. (A.L.B.)

  17. Rapport financier trimestriel pour le trimestre qui a pris fin le 30

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    30 sept. 2011 ... politiques, de chercheurs et de collectivités de par le monde. ..... Financement : le CRDI est visé par l'Examen stratégique et ... Le Conseil des gouverneurs a amorcé la planification du recrutement du nouveau président.

  18. Politiques Economiques et Pauvreté A qui profitent les dépenses ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    drivard

    Réseau Politiques Economiques et Pauvreté (PEP)-www.pep-net.org ... d'équité que les autorités publiques mettront au cœur de leurs stratégies de ...... des structures scolaires et recruter des enseignants pour y scolariser les enfants. .... investissements et abrite tous les ministères, les ambassades, les grandes entreprises.

  19. OPS : élaborer de nouveaux partenariats et consolider ceux qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    9 mai 2011 ... Involving urban communities in controlling dengue fever in Latin America. Research shows that an integrated approach to dengue control—focusing on ecological, biological, and social factors—can reduce vector densities. View moreInvolving urban communities in controlling dengue fever in Latin ...

  20. ¿Quién fue Lluís Montané i Mollfulleda?

    OpenAIRE

    Balius i Juli, Ramon

    2006-01-01

    Lluís Montané i Mollfulleda, nacido en Sant Celoni en 1905, era un artista integral, enmarcado en las corrientes novecentistas y mediterranistas que se sustentan en la tradición clásica del mundo griego. Estudió en la Escuela de Bellas Artes de Barcelona (Llotja) entre 1921 y 1927, aunque antes, muy joven, trabajó durante tres años en el taller del escultor Eusebi Arnau (1864-1933). En la Llotja su segundo maestro, después del profesor de primer curso, Parera, fue Antoni Alsina i Amils (1864-...

  1. Un accélérateur de particules qui redouble d'énergie

    CERN Multimedia

    Dumas, Cécile

    2007-01-01

    On a very short distance, physicists have doubled the energy of particules propeled in an accelerator. A new technics that could improve the performances of these instruments without increasing costs. (1/2 page)

  2. ¿Quién paga por la paz en Colombia?

    Directory of Open Access Journals (Sweden)

    Vanda Felbab-Brown

    2016-12-01

    Full Text Available Este artículo examina los costos políticos que habrán de asumir las FARC, las fuerzas armadas, los políticos derechistas, la élite y los intereses creados, las personas desplazadas, los cultivadores de coca y la clase media. El análisis también aborda el papel y el impacto de otros actores, como las Bacrim y los grupos guerrilleros que aún siguen operando, incluido el ELN.

  3. ¿Quién teme al periódico digital?

    Directory of Open Access Journals (Sweden)

    Dra. Lucía Martínez Odriozola

    1999-01-01

    Full Text Available En un momento en que hablar de los diarios en Internet está de moda y en el que se hacen cábalas constantemente con el futuro de la prensa tradicional y su sustitución por los denominados periódicos digitales, el presente trabajo, basado en un estudio realizado en el País Vasco (UPV-EHU, pone en cuestión que en realidad estos últimos sean, de momento, una amenaza real para los diarios convencionales.Ni empresarialmente, ya que ambas versiones, papel y digital, pertenecen a la misma empresa editora; ni periodísticamente, porque las ediciones digitales son un mero volcado o copia de las de papel, que no aprovechan las prácticamente infinitas posibilidades que les otorga el soporte electrónico ni han creado un lenguaje propio para el nuevo medio.

  4. Rapport financier trimestriel pour le trimestre qui a pris fin le 30 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    30 sept. 2017 ... Régi par la Loi sur le Centre de recherches pour le développement international ... forme des leaders dans les secteurs de l'administration publique, de la .... Plus des trois quart du manque à gagner prévu de 11,6 millions.

  5. Rapport financier trimestriel pour le trimestre qui a pris fin le 31 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sophie Comeau

    31 déc. 2017 ... Régi par la Loi sur le Centre de recherches pour le développement international ... optimiser les retombées; forme des leaders dans les secteurs de ... Centre dans ce domaine, et a animé une table ronde avec trois des quatre ...

  6. Refugiados climáticos: ¿quién debe cargar los costos?

    Directory of Open Access Journals (Sweden)

    Daniel Loewe

    Full Text Available El artículo¹ argumenta a favor del concepto de "refugiado climático" y sostiene que la responsabilidad por su desplazamiento así como los costos asociados, incluyendo su recepción en otros Estados, deben ser asignados entre los Estados en razón de su uso del recurso atmosférico así como del beneficio que ese uso les reporta.

  7. ¿Quién es el culpable? La semiótica de Eco

    Directory of Open Access Journals (Sweden)

    Iván Oñate

    2015-01-01

    Full Text Available Este artículo aborda un aspecto por el cual Umberto Eco no se hizo mundialmente famoso, pero que sin lugar a dudas habla de su erudición y sin cuyos antecedentes su novelística no tendría determinadas características que la identifican. Este aspecto es el que fundamentalmente dice que Umberto Eco es un semiólogo.

  8. Capacités en science du comportement pour relever les facteurs qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Pour combler cette importante lacune, ce projet financera les études de maîtrise d'un étudiant nigérian en psychologie à l'Université d'Ottawa. Cette formation aidera à concevoir des outils et des stratégies pour cerner les principaux obstacles et facteurs de motivation psychosociaux relatifs à la participation et à la rétention ...

  9. LA COLONNE SANS FIN, LE THÉÂTRE QUI UNI T LES MONDES

    Directory of Open Access Journals (Sweden)

    Lăcrămioara BERECHET

    2017-05-01

    Full Text Available The reading of Mircea Eliade ’ s drama writing The Endless Column ( Coloana nesfârșită is meant to focus on the writer ’ s play by using operators that are specific to textuality and myth as a literary method. As for the acting in a mise - en - scene context, the perspective of anthropology and religious phenomenology, announced in the inner and outer didascalies of the text, anchors the interpretation i n the context of Mircea Eliade's work both at literary and scientific level. The theoretical perspective comes closer to its critical testimonies regarding Eliade's drama experiment and have shaped a first level of perception, by considering the play to be long to the Living Theater current, especially owing to Monique Borie. In this context, Mircea Eliade ’ s plays are in line with Grotowski, Peter Brook, and tries to present a sensitive world on stage, by means of a symbolic language specific to drama. Moldi ng the sign of ‘ reality ’ into a mythical register can be confirmed both at the level of the text and at the level of mise en scene. The reading of Mircea Eliade ’ s drama writing The Endless Column ( Coloana nesfârșită is meant to focus on the writer ’ s play by using operators that are specific to textuality and myth as a literary method. As for the acting in a mise - en - scene context, the perspective of anthropology and religious phenomenology, announced in the inner and outer didascalies of the text, anchors the interpretation i n the context of Mircea Eliade's work both at literary and scientific level. The theoretical perspective comes closer to its critical testimonies regarding Eliade's drama experiment and have shaped a first level of perception, by considering the play to be long to the Living Theater current, especially owing to Monique Borie. In this context, Mircea Eliade ’ s plays are in line with Grotowski, Peter Brook, and tries to present a sensitive world on stage, by means of a symbolic language specific to drama. Moldi ng the sign of ‘ reality ’ into a mythical register can be confirmed both at the level of the text and at the level of mise en scene.

  10. CONTRE LA MIMESIS. THÉÂTRE QUI RECOMPOSE DE MANIÈRE PARADISIAQUE

    Directory of Open Access Journals (Sweden)

    Lăcrămioara BERECHET

    2017-05-01

    Full Text Available The present study approaches two plays of Mircea Eliade, Iphigenia and People and Stones ( Oameni și pietre .The mythical theme that builds the dramatic narrativityof the first play analyzes the cosmological sacrifice, whereas in the second play the characters question poetry’s orphicmission. The dramatic object of the two texts is unnamed, as in any mystical experience. Mircea Eliade’s theater poses the conceptual problem of a mimesis with "no mo del", which is why we gloss upon a form of antimimesis in Eliade's theatricality.

  11. Quiere saber quién es Anastasia Candre? Amigo lector, aquí estoy

    Directory of Open Access Journals (Sweden)

    Anastasia Candre Yamacuri

    2014-09-01

    Full Text Available Este texto autobiográfico de Anastasia Candre fue compuesto a partir de fuentes inéditas en español y uitoto y fragmentos de fuentes publicadas. Está dividido en ocho partes. En la primera, Anastasia cuenta sobre su niñez, el aprendizaje junto a sus padres y hermanos hasta su ingreso al internado indígena. En la segunda parte, narra sobre su llegada a Leticia, sus trabajos allí y su estudio de bachillerato. En la tercera parte, relata sobre su época de estudiante de lingüística en la Universidad Nacional de Colombia. En la cuarta parte habla sobre su investigación del ritual del dios de las cosechas y su encuentro con el anciano Jimuizɨtofe. En la quinta parte, hace un relato de sus actividades como cantora y bailarina, incluyendo imágenes de sus presentaciones. En la sexta parte se refiere a su trabajo como pintora y se reproducen imágenes de varias de sus obras. En la séptima parte se refiere a su incursión en la poesía y se reproducen dos poemas publicados y uno inédito. En la octava parte habla sobre sus sueños y concluye con un poema inédito. El texto contiene también un listado de la trayectoria de Anastasia: premios, publicaciones, informes, exposiciones, ponencias y presentaciones, y actividades de docencia.

  12. Qui sera le nouvel Einstein ? Vers une nouvelle theorie de la gravitation

    Science.gov (United States)

    Bonnet-Bidaud, J. M.

    1999-10-01

    Un debat de plus d'un siecle a resurgi ces toutes dernieres annees avec une vigueur nouvelle. L'enjeu ? Mettre fin, ni plus ni moins, a l'une des contradictions les plus inouies de la physique fondamentale, en reconciliant mecanique quantique et relativite generale. En effet, a l'heure ou la gravitation semble enfin sur le point de fusionner avec les trois autres forces de la nature. il est certain que la relativite d'Einstein doit etre bientot remplacer par une autre theorie... Reste quye tous les physiciens sont loin de s'accorder sur la marche a suivree. Gravitation quantique, relativite d'echelle, supersymetrie, les candidates ne manquent pas.

  13. Déchiffrer les mécanismes cognitifs et neuronaux qui sous-tendent l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ce projet cherche à comprendre les mécanismes cérébraux nécessaires pour permettre aux gens d'apprendre à percevoir les sons. Circuits neuronaux et apprentissage. L'équipe de recherche étudiera des personnes avec et sans formation musicale pour évaluer leur capacité d'apprendre des motifs sonores.

  14. Dime qué tango quieres y te diré quién eres

    Directory of Open Access Journals (Sweden)

    María de los Angeles Montes

    2016-01-01

    Full Text Available [es] Las músicas populares representan lugares de incalculable valor para la construcción de narrativas identitarias, especialmente en el ámbito de su recepción. Escuchar tango, salsa o cuarteto cordobés es también un modo de decirle al mundo el lugar social que ocupamos o, más exactamente, en qué lugar simbólico queremos ser ubicados, en función de los valores que atribuimos a esas músicas. En el presente trabajo se analiza cómo las opciones realizadas en el ámbito de la recepción del tango por parte de los milongueros de la ciudad de Córdoba, les sirven a estos milongueros a para construir sus identidades sociales, una imagen valorada de sus propias competencias y, con ella, de sí mismos. Es, precisamente, en la puesta en valor de sus propias competencias donde podemos encontrar claves para comprender la selección del tango (y de cuáles tangos, dentro del vasto abanico de músicas populares a su disposición. Esta comunicación ofrece una lectura en clave sociodiscursiva de la recepción del tango en Córdoba, atravesada por cuestiones de clase, de identidad nacional y de género. [en] Popular music represents a place of invaluable importance when it comes to the construction of a narrative identity, particularly, in the field of its reception. Listening to tango, salsa, or the popular music of Córdoba (called “Cuarteto Cordobés is also a way of telling the world the social place we occupy or, more precisely, in which symbolic place we want to be located, depending on the values we confer to that music. In this paper, I analyze the way in which the choices made in the reception of tango by the dancers of the city of Córdoba are used by these milongueros (social tango dancers to build their social identities, an appraised image of their own competences, thus of themselves. It is in that very appraisal of their competences where we can find the key to understand their choosing tango (and which tango songs within a vast range of popular music available. This communication provides an interpretation in sociodiscursive key of the reception of tango in Cordoba, crossed through by class, gender, and national identity.

  15. ¿Quién es el dueño de la pantalla?

    Directory of Open Access Journals (Sweden)

    Juan Carlos Gómez Jaramillo

    2006-05-01

    Full Text Available A partir de 1990 la legislación colombiana ha tenido significativos avances para permitir que todas las personas puedan acceder a los servicios de telecomunicaciones, tal como corresponde en ejercicio del derecho fundamental del acceso a la información. Gracias al desarrollo de la tecnología, la limitación que generaba la necesidad de utilizar frecuencias radioeléctricas ya no es una razón válida desde el punto de vista constitucional para restringir el establecimiento de nuevos servicios y la difusión de información. Esta realidad técnica debe ser reconocida por el ordenamiento jurídico respecto de todos los servicios de telecomunicaciones. Dentro del actual marco constitucional no existe ningún fundamento para que los servicios que no utilicen frecuencias radioeléctricas sean objeto de reserva estatal. Este reconocimiento ya lo hizo el legislador al establecer que el servicio de telefonía pública básica conmutada local no sea objeto de concesión. En el mismo sentido, los medios masivos de comunicación, incluida la televisión, que no requieran el uso de frecuencias radioeléctricas y que puedan ser trasmitidos a través de redes de cable, gozan del derecho constitucional de establecerse libremente, aunque deben someterse a los reglamentos del servicio que establezca la autoridad competente. Las disposiciones legales que actualmente no permiten el ejercicio de tal derecho, son inconstitucionales. / Since 1990 Colombian telecommunication law has had significant advances allowing everybody access to telecommunication services in exercise of the fundamental right of information. Technology development permit that the limitation which generated the need of use frequencies, know days is not a valid reason -from a constitutional point of view- to restrict the operation of new telecommunication services and the information diffusion. This technical reality, have to be recognize in the legal order among all the telecommunication services. Colombian constitutional framework, does not has any rule that allow the restriction of telecom services which do not use frequencies under a "state reserve regime". Legal recognition in this sense, has been made by the legislator, when he established that the local telephony service does not required concession for its operation. In the same sense, massive media operators -including television operators- which do not use frequencies and which can be transmitted by wires, can be freely established observing only the specific service regulation dictated by the telecommunication authority. Legal dispositions that today do not allow the exercise of this constitutional right are illegal.

  16. Sociedad, infancia y adolescencia, ¿de quién es la dificultad?

    Directory of Open Access Journals (Sweden)

    Lourdes Gaitán Muñoz

    2010-01-01

    Full Text Available Este artículo pretende ser una invitación a un viaje en el que no se den por hechas las seguridades compartidas acerca de la realidad de los niños y adolescentes de hoy, sino que se pongan en cuestión, buscando para ello otras explicaciones alternativas, que nos habiliten para abordar el estudio de las vidas de los niños, o las intervenciones con niños (sean ellos o nosotros quienes nos encontremos en dificultad con una mirada distinta. En primer lugar se analiza el proceso de construcción social del propio concepto de “infancia y adolescencia en dificultad”, a la luz de los cambios que se han producido, especialmente a lo largo del último siglo, en las ciencias sociales y su repercusión en la formación de una idea de infancia en el imaginario colectivo. En segundo término, se aborda la condición de ser niño o adolescente en la llamada “sociedad del riesgo”, caracterizada, entre otras cosas, por la incertidumbre y los deseos de alcanzar un cierto control sobre los peligros percibidos como potenciales. La percepción de los riesgos para la infancia en la sociedad tiene dos caras: por un lado los peligros a los que están expuestos y por otro aquellos que causan, esto es, lo que nos amenaza. Para conjurar estos riesgos se exige mayor control por parte de las instituciones que regulan la vida de los niños (la familia, la escuela o el sistema de protección. El resultado es una restricción de la autonomía de los niños, niñas y adolescentes, que contrasta con las expectativas de que, como “hijos de la modernidad”, sean capaces de elegir sus propios caminos de autorrealización.-------------------------------------------------------------------This article tries to be an invitation to a journey in which the shared safeties taken for granted on the reality of the children and today teenagers, are being put in question, looking for other alternative explanations, which enable us to approach the study of the lives of the children, or the interventions with children (be they or we who meet in difficulty with a different look. First it is analyzed the process of social construction of the proper concept of "childhood and adolescence in difficulty", in the light of the changes that have taken place, specially throughout last century, in the social sciences and its repercussion in the social images of childhood. In the second term, it is approached the condition to be child or teenager in so called "risk society", characterized, among other things, by the uncertainty and the desires to reach a certain control on the dangers perceived as potentials. The perception of the risks for the childhood in the society has two faces: on the one hand the dangers to those who are exposed and for other one those that they cause, which threatens us. To conspire these risks it is required major control on the part of the institutions that regulate the life of the children (the family, the school or the protection system. The result is a restriction of the autonomy of the children and teenagers, which confront with the expectations of whom, as " children of the modernity ", are capable of choosing their own ways of self-realization. 

  17. "La meilleure chose qui me soit arrivée" / Toomas Hendrik Ilves ; interv. Sabine Verhest

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2009-01-01

    Eesti riigipea räägib eestlaste ootustest ja võimalustest Euroopa Liidus, eurole üleminekust, majanduskriisiga toimetulemisest, Euroopa Liidu laienemisest, kandidaatidest Euroopa Ülemkogu eesistuja kohale

  18. Exposition des ymages des figures qui sunt: discourses about images in Medieval Occident

    Directory of Open Access Journals (Sweden)

    Maria Cristina Correia Leandro Pereira

    2016-09-01

    Full Text Available Contrary to what indicates the famous – and questionable – formula "Bible des illetrés”, the medieval discourses on images went well beyond just highlighting its didactic function. In this article, we present a sample of this diversity, analyzing a number of medieval texts dealing with images, which we have divided into five broad categories (not mutually exclusive: on the contrary, sometimes complementary. The first and most numerous are the theoretical discourses on images involving theological questions. Then, still based on arguments of theological order, a second group corresponds to those texts that seek to intervene in the practice of images through normative propositions. As a result from the previous two types is the third group: the speeches dealing with the reception of images and the reactions they cause. A fourth group are the writings that mention the producers of images: both practical documents and those that express value judgments about their Works. And finally, there are texts that describe the images, both their iconographic content and their materiality.

  19. ¿Quién fue Lluís Montané i Mollfulleda?

    Directory of Open Access Journals (Sweden)

    Ramon Balius i Juli

    2006-06-01

    Full Text Available Lluís Montané i Mollfulleda, nacido en Sant Celoni en 1905, era un artista integral, enmarcado en las corrientes novecentistas y mediterranistas que se sustentan en la tradición clásica del mundo griego. Estudió en la Escuela de Bellas Artes de Barcelona (Llotja entre 1921 y 1927, aunque antes, muy joven, trabajó durante tres años en el taller del escultor Eusebi Arnau (1864-1933. En la Llotja su segundo maestro, después del profesor de primer curso, Parera, fue Antoni Alsina i Amils (1864-1948, el cual, como comentaremos, fue el más apreciado. Montané quiso conocer el mundo de su arte y después de una beca, en 1926, para realizar estudios por España, ganó por concurso, en 1928, una pensión de la Diputación de Barcelona para ampliar estudios en Italia, Francia y Bélgica. En Bélgica estudió de cerca la obra de Constantin Meu­nier (1831-1905. En 1930, en París, frecuentó la Grande Chaumière donde todavía se respiraban les ideas y las directrices de Auguste Rodin (1840-1917 y de Antoine Bourdelle (1861-1929. Antes había estado en Italia, en Florencia y Roma, en la Academia de Bellas Artes de España, al lado del maestro Miquel Blay (1866-1936 en donde, mientras mejoraba su aprendizaje, pudo contemplar en los museos de Roma y Nápoles, las esculturas de los autores clásicos. En 1931 donó a la Generalitat de Catalunya su obra Joguinera (Juguetona realizada durante su estancia por Europa. Esta escultura se ubicó en el despacho del presidente Macià y actualmente se encuentra en el Centro de Cultura Contempo­ránea.

  20. «Qui patrie excidium intulerunt». Hispania 711: Desperate explanations for an unexpected collapse

    Directory of Open Access Journals (Sweden)

    Pablo C. Díaz

    2016-09-01

    Full Text Available The fall of the Visigothic Kingdom of Toledo from the Muslim incursion in the year 711 has been generally explained by specialists as an inevitable consequence of a disintegration process in the Visigothic power structures. Historians have associated this situation to a confrontation – either direct or indirect – between Hispanic-Visigothic monarchy and aristocracy, being the standstill of the kingdom (caused by its administrative, military and judicial institutional incapacity also considered. In this paper, as opposed to the fatalistic perspective where the idea of an inevitable end was irrationally imposed, a different explanation is proposed based on the multiple power dynamics, the Kingdom’s defense mechanisms and the last Visigothic monarchs’ legislative activity. All these ideas will be framed into the context of the (unstable normality and the efficacy of the Visigothic institutional machinery.

  1. ¿Quiénes son los sentenciados por homicidio intencional en México?

    OpenAIRE

    Vilalta, Carlos

    2015-01-01

    Se presenta un perfil preliminar del homicida intencional en México. De esta forma se dan los primeros pasos empíricos en la construcción de un conocimiento sistemático y comparativo del delincuente violento. Se comparó al total de condenados por homicidio intencional frente al total de condenados por otros delitos federales intencionales entre 1997 y 2010. Se encontró que el total de sentenciados por este delito en el fuero federal es muy reducido, su número varía mucho entre años y cada vez...

  2. AIDS Review 2005 : Qu'est-ce qui mijote ? Le sida et la politique ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Giving girls and women the power to decide. Addressing Africa's unmet need for family planning by intensifying sexual and reproductive and adolescent health research. View moreGiving girls and women the power to decide ...

  3. Et le pouce, où est-il, qui montrera vers le ciel? (Sonnet XXXII

    Directory of Open Access Journals (Sweden)

    Miha Pintarič

    2012-12-01

    Full Text Available Lʼarticle soumet à une brève analyse les Sonnets romains dʼAndrej Capuder, homme de politique, diplomate, professeur dʼuniversité, écrivain, traducteur et poète. Le passé et le souvenir mélancolique de lʼamour de jeunesse, lʼavenir et la rencontre prochaine avec Dieu, entre lʼun et lʼautre, tant de choses si terrestres, tantôt jugées avec sévérité, tantôt tolérées et tantôt même rendues complices.

  4. pour le trimestre qui a pris fin le 30 juin 2013

    International Development Research Centre (IDRC) Digital Library (Canada)

    Office 2004 Test Drive User

    30 juin 2013 ... Conseil des gouverneurs du CRDI. Le mandat des gouverneurs suivants a pris fin le 27 mai 2013 : Margaret Biggs, d'Ottawa, en Ontario;. Faith Mitchell, de Washington, aux États-Unis; Elizabeth Parr-Johnston, de Chester Basin, en Nouvelle-Écosse; Gordon Shirley, de Kingston, en Jamaïque; l'honorable ...

  5. Maíz transgénico: ¿Beneficio para quién?

    Directory of Open Access Journals (Sweden)

    Bethel Marina Luna Mena

    2015-01-01

    Full Text Available En la introducción se comentan algunas de las consecuencias ecológicas, agronómicas, socioeconómicas y culturales de la liberación comercial de maíz transgénico en México. Posteriormente, se describe la situación actual del proceso de concentración y privatización en la producción y comercio de semillas a nivel mundial y de manera particular en México. Luego, se mencionan las oportunidades y alternativas que existen ante la situación descrita previamente. Así, se indican los aspectos relacionados con las patentes biotecnológicas dentro del contexto internacional y los Derechos de Obtentor, seguido del análisis de las propuestas de reformas a la Ley Federal de Variedades Vegetales del país. El documento finaliza con una discusión general y con las conclusiones.

  6. Des agriculteurs déterminent les innovations et les pratiques qui ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    16 sept. 2013 ... Les chercheurs ont constaté que les agriculteurs préféraient des cultures de valeur élevée telles que le mil et le sorgho au maïs, car elles se vendent à meilleur prix et résistent mieux à la sécheresse. Les agriculteurs apprécient tout particulièrement le sorgho gadam parce qu'il existe déjà un client local, ...

  7. Relations entre acides gras oméga-3, oméga-9, structures et fonctions du cerveau. Le point sur les dernières données. Le coût financier alimentaire des oméga-3 « Je chercherai à connaître les différences qui existent entre les huiles de faine, de colza, d’olive, de noix ». Honoré de Balzac. « Histoire de César Birotteau ».

    Directory of Open Access Journals (Sweden)

    Bourre Jean-Marie

    2003-05-01

    Full Text Available Pour ce qui concerne le cerveau, les acides gras ω3 ont été plus spécialement étudiés que les acides gras ω6 ou ω9. La carence en acide alpha-linolénique (18 :3 ω3 altère la structure et la fonction des membranes, et entraîne de légers dysfonctionnements cérébraux, comme cela a été montré sur les modèles animaux puis chez les nourrissons humains. Les résultats récents ont montré que son déficit alimentaire induit des anomalies plus marquées dans certaines structures cérébrales que dans d’autres, le cortex frontal et l’hypophyse étant les plus touchés. Ces singularités sont accompagnées de perturbations comportementales qui touchent plus particulièrement certains tests (habituation, adaptation à une situation nouvelle. Les anomalies biochimiques et comportementales sont partiellement réversées par une supplémentation avec des phospholipides, notamment extraits d’oeuf enrichis en ω3 ou de cervelle de porc. Une étude effet-dose montre que les phospholipides d’origine animale sont plus efficaces que ceux d’origine végétale pour réverser les conséquences du déficit, dans la mesure, entre autres, où ils apportent les très longues chaînes pré-formées. La déficience en acide alpha-linolénique se traduit au niveau du cortex frontal de rat par des perturbations de la neurotransmission mono-aminergique. Mais ne sont touchées ni la densité ni la fonction des transporteurs de la dopamine. Chez l’animal carencé, la réversibilité dans la neurotransmission dopaminergique (dans le cortex préfrontal, entre autres n’est que partielle après arrêt du déficit alimentaire. La carence en acide alpha-linolénique diminue la perception du plaisir, en altérant légèrement l’efficacité des organes sensoriels et en affectant certaines structures cérébrales. Cette carence modifie le métabolisme énergétique du cerveau en perturbant le transport du glucose. Au cours du vieillissement, la baisse

  8. Il lavoro penitenziario: la dimensione umana del carcere e della città che lo accoglie. L’esperienza della cooperativa sociale Rio Terà dei Pensieri/Le travail carcéral : la dimension humaine de la prison et de la ville qui l'abrite. L'expérience de la coopérative sociale Rio Terà dei Pensieri/Prison inmates work: the human dimension of the prison and the town where prison is built in. The experience of social cooperative Rio Terà dei Pensieri

    Directory of Open Access Journals (Sweden)

    Valentina Ferrara

    2013-12-01

    Full Text Available Il lavoro approfondisce, nella parte teorica, le tematiche relative alla pena detentiva, analizzando la tradizione sociologica sull’argomento e confrontandola con le contingenze attuali, ponendo specifica attenzione al «problema» dell’immigrazione; traccia in seguito il quadro normativo relativo al lavoro in carcere e, contestualmente, alle cooperative sociali, quale cornice entro cui presentare i dati afferenti alla parte empirica. La ricerca di approccio quantitativo ha analizzato i dati dei dipendenti della Cooperativa al fine di rilevare la porzione di posti di lavoro garantiti dalla stessa rispetto al totale dei detenuti della Regione Veneto e della città di Venezia; la ricerca di approccio qualitativo ha indagato l’impatto delle attività della Cooperativa all’interno del carcere (osservazione, trattamento, misure alternative e al suo esterno (percezione dei cittadini rispetto agli istituti penitenziari. La première partie de cet article s’attache à analyser certains aspects de la détention à travers la littérature sociologique et accordant une attention particulière aux « problèmes » d’immigration. Ensuite, l’auteur examine les lois sur l’emploi en milieu carcéral et, parallèlement, les coopératives sociales. Dans la deuxième partie, l’auteur prend en considération les données provenant d’une étude quantitative menée parmi les salariés de la coopérative Rio Terà dei Pensier dans le but d’estimer le pourcentage d’emplois assuré par cette coopérative par rapport au nombre total de détenus en Région de Vénétie et dans la ville de Venise. De plus, en ce qui concerne la partie qualitative de cette recherche, l’auteur se penche sur l’impact des activités menées par cette coopérative tant en prison (traitement et réinsertion des délinquants, mesures alternatives à la détention qu’à l’extérieur (les perceptions qui ont les citoyens de la prison. The first part of this article

  9. 77 FR 39561 - Advanced Braking Technologies That Rely on Forward-Looking Sensors; Request for Comments

    Science.gov (United States)

    2012-07-03

    .... Mail: Docket Management Facility, U.S. Department of Transportation, 1200 New Jersey Avenue SE., West... surrogate vehicles representing various vehicle body styles that any system would encounter in the real world to ensure robustness? If there is such a need, describe what body styles should comprise the fleet...

  10. Does the applicability of Bacillus strains in probiotics rely upon their taxonomy?

    Science.gov (United States)

    Safronova, L A; Zelena, L B; Klochko, V V; Reva, O N

    2012-02-01

    The taxonomic position and biological activities of two Bacillus strains used in veterinary probiotics were studied in this work. These microorganisms inhibit growth of a broad spectrum of pathogenic cultures. They synthesize proteolytic enzymes and other biologically active metabolites, and to some extent, supplement each other with probiotic activities. It is not clear whether these versatile activities are properties of individual strains or bacterial taxa as whole. 16S rRNA comparisons were conducted and illustrated the relatedness of these strains to Bacillus amyloliquefaciens . Their cell wall fatty acid contents were consequently analysed and specified a relation to the " Bacillus velezensis " ecomorph. On account of the previous observations, a simple method of 16S rRNA profiling by polymorphic nucleotides was proposed to determine a group of organisms closely related to "B. velezensis" and B. amyloliquefaciens subsp. plantarum, for they are biologically active strains suitable for use in biotechnology. The extreme genetic plasticity of these bacteria endowed each strain with a unique spectrum of antagonistic activity.

  11. Enhancing memory performance after organic brain disease relies on retrieval processes rather than encoding or consolidation

    NARCIS (Netherlands)

    Hildebrandt, H.; Gehrmann, A.; Mödden, C.; Eling, P.A.T.M.

    2011-01-01

    Neuropsychological rehabilitation of memory performance is still a controversial topic, and rehabilitation studies have not analyzed to which stage of memory processing (encoding, consolidation, or retrieval) enhancement may be attributed. We first examined the efficacy of a computer training

  12. Persistent identifiers for web service requests relying on a provenance ontology design pattern

    Science.gov (United States)

    Car, Nicholas; Wang, Jingbo; Wyborn, Lesley; Si, Wei

    2016-04-01

    Delivering provenance information for datasets produced from static inputs is relatively straightforward: we represent the processing actions and data flow using provenance ontologies and link to stored copies of the inputs stored in repositories. If appropriate detail is given, the provenance information can then describe what actions have occurred (transparency) and enable reproducibility. When web service-generated data is used by a process to create a dataset instead of a static inputs, we need to use sophisticated provenance representations of the web service request as we can no longer just link to data stored in a repository. A graph-based provenance representation, such as the W3C's PROV standard, can be used to model the web service request as a single conceptual dataset and also as a small workflow with a number of components within the same provenance report. This dual representation does more than just allow simplified or detailed views of a dataset's production to be used where appropriate. It also allow persistent identifiers to be assigned to instances of a web service requests, thus enabling one form of dynamic data citation, and for those identifiers to resolve to whatever level of detail implementers think appropriate in order for that web service request to be reproduced. In this presentation we detail our reasoning in representing web service requests as small workflows. In outline, this stems from the idea that web service requests are perdurant things and in order to most easily persist knowledge of them for provenance, we should represent them as a nexus of relationships between endurant things, such as datasets and knowledge of particular system types, as these endurant things are far easier to persist. We also describe the ontology design pattern that we use to represent workflows in general and how we apply it to different types of web service requests. We give examples of specific web service requests instances that were made by systems at Australia's National Computing Infrastructure and show how one can 'click' through provenance interfaces to see the dual representations of the requests using provenance management tooling we have built.

  13. The power of hope: being a doctor is more than relying solely on the numbers.

    Science.gov (United States)

    Godshalk, A N; Brown, G C; Brown, H C; Brown, M M

    2008-06-01

    To ascertain whether a physician's positive or negative attitude significantly impacts the quality of life of ophthalmic patients. A standardised, validated, time trade-off, utility instrument was administered to consecutive vitreoretinal patients by interview to assess the quality of life associated with their current ocular health state (baseline scenario). Each was then given a scenario for the exact same health state with the same long-term prognosis in which their doctor emphasised the possible negative consequences (bad-news scenario) and one for the same health state in which their doctor emphasised the positive consequences (good-news scenario). Among the 247 patients enrolled were 140 women (57%) and 107 men (43%) with a mean age of 66 years and a mean educational level of 13.8 years after kindergarten. The mean baseline utility for 247 patients was 0.87 (SD = 0.19; 95% CI 0.84 to 0.89). The mean bad-news scenario utility was 0.80 (SD = 0.22, 95% CI 0.78 to 0.83), a 70% diminution in quality of life compared with the mean baseline utility (p = 0.0009). The mean good-news scenario utility was 0.89 (SD = 0.18, 95% CI 0.86 to 0.91), an insignificant difference compared with the mean baseline utility (p = 0.26). Ocular patients had a considerably poorer quality of life when their physician emphasised the possible negative consequences associated with their eye disease(s), as opposed to a more positive approach. While at times necessary, a negative emphasis approach can theoretically result in a considerable loss of life's value.

  14. Monkeys Rely on Recency of Stimulus Repetition When Solving Short-Term Memory Tasks

    Science.gov (United States)

    Wittig, John H., Jr.; Richmond, Barry J.

    2014-01-01

    Seven monkeys performed variants of two short-term memory tasks that others have used to differentiate between selective and nonselective memory mechanisms. The first task was to view a list of sequentially presented images and identify whether a test matched any image from the list, but not a distractor from a preceding list. Performance was best…

  15. Gustatory Habituation in "Drosophila" Relies on "Rutabaga" (Adenylate Cyclase)-Dependent Plasticity of GABAergic Inhibitory Neurons

    Science.gov (United States)

    Paranjpe, Pushkar; Rodrigues, Veronica; VijayRaghavan, K.; Ramaswami, Mani

    2012-01-01

    In some situations, animals seem to ignore stimuli which in other contexts elicit a robust response. This attenuation in behavior, which enables animals to ignore a familiar, unreinforced stimulus, is called habituation. Despite the ubiquity of this phenomenon, it is generally poorly understood in terms of the underlying neural circuitry. Hungry…

  16. Improving listening comprehension skills relying on metacognitive strategies - focus on vocabulary and specific l2 instruction

    Directory of Open Access Journals (Sweden)

    Jerotijević-Tišma Danica

    2016-01-01

    Full Text Available The present paper aims at investigating the application of an instructional method specifically focused on the expansion of metacognitive awareness and its effect on Serbian EFL students’ listening comprehension. The current study is a follow-up research of a similar study by Vandergrift and Tafaghodtari (2010. However, we sought to expand the previous research by investigating the relationship between the students’ current level of L2 (target language vocabulary and listening test scores. Our study likewise differed in the sample of participants, the target language, teaching and testing material used, and the duration of the very experiment. To answer the proposed research questions we conducted an experiment with 57 Serbian secondary school EFL (English as a Foreign Language learners divided into experimental (n=27 and control group (n=30. The results of the pre- and post-tests of the two groups showed the beneficial effects of developing metacognitive strategies and the strong positive correlation between the level of vocabulary and listening comprehension. The paper underlines important pedagogical implications especially regarding the enhancement of metacognitive awareness and vocabulary proficiency of students in order to improve performance on listening comprehension tasks.

  17. DESIGN OF DYNAMIC VOLTAGE RESTORER TO ENHANCE POWER QUALITY RELYING ON RENEWABLE SOURCE

    Directory of Open Access Journals (Sweden)

    Haider M. Umran

    2018-05-01

    Full Text Available Power quality improvement of low voltage grid is a great challenge that confronts the sophisticated power applications, because their performance is highly sensitive to the quality of power supply. Dynamic Voltage Restorer (DVR used widely as an efficient and skillful device to adjust electrical disturbances of the distribution grids. This paper introduces an overview of the components of the 3-phase dynamic voltage restorer and design its own control circuit. The performance of DVR was developed on the basis of the appropriate selection of Photovoltaic (PV module instead of the present conventional designs. Through this design, the need of series converter (DVR for the current from an electrical grid will end and the problems of power losses will curb. The PV-module is selected to meet the requirements of the DVR during voltage sag/swell on voltage line. The proposed system is mimicked in MATLAB software/Simulink and the findings are presented to prove the success of the design in terms of: Full congruence of the load voltage waveform with source voltage waveform, attaining 0.77% of THD analysis for the load voltage and the waveforms of PV system.

  18. Arsenate tolerance in Silene paradoxa does not rely on phytochelatin-dependent sequestration

    International Nuclear Information System (INIS)

    Arnetoli, Miluscia; Vooijs, Riet; Bookum, Wilma ten; Galardi, Francesca; Gonnelli, Cristina; Gabbrielli, Roberto; Schat, Henk; Verkleij, Jos A.C.

    2008-01-01

    Arsenate tolerance, As accumulation and As-induced phytochelatin accumulation were compared in populations of Silene paradoxa, one from a mine site enriched in As, Cu and Zn, the other from an uncontaminated site. The mine population was significantly more arsenate-tolerant. Arsenate uptake and root-to-shoot transport were slightly but significantly higher in the non-mine plants. The difference in uptake was quantitatively insufficient to explain the difference in tolerance between the populations. As accumulation in the roots was similar in both populations, but the mine plants accumulated much less phytochelatins than the non-mine plants. The mean phytochelatin chain length, however, was higher in the mine population, possibly due to a constitutively lower cellular glutathione level. It is argued that the mine plants must possess an arsenic detoxification mechanism other than arsenate reduction and subsequent phytochelatin-based sequestration. This alternative mechanism might explain at least some part of the superior tolerance in the mine plants. - Neither decreased uptake nor phytochelatins seem to play a role in the As tolerance in Silene paradoxa

  19. Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity

    DEFF Research Database (Denmark)

    Köpper, Frederik; Bierwirth, Cathrin; Schön, Margarete

    2013-01-01

    knockdown of the MAP kinase-activated protein kinase 2 (MK2), a kinase currently implicated in p38 stress signaling and G2 arrest. Depletion or inhibition of MK2 also protected cells from DNA damage-induced cell death, and mice deficient for MK2 displayed decreased apoptosis in the skin upon UV irradiation...

  20. Wide dispersal of aphid-pathogenic Entomophthorales among aphids relies upon migratory alates.

    Science.gov (United States)

    Feng, Ming-Guang; Chen, Chun; Chen, Bin

    2004-05-01

    Entomophthoralean mycoses are of general importance in the natural control of aphids, but mechanisms involved in their dissemination are poorly understood. Despite several possible means of fungal survival, the dispersal of the mycoses in aphids has never been related to the flight of their migratory alates that are able to locate suitable host plants. In this study, aphid-pathogenic fungi proved to be widely disseminated among various aphids by their alates through migratory flight based on the following findings. First, up to 36.6% of the 7139 migratory alates (including nine species of vegetable or cereal aphids) trapped from air > 30 m above the ground in three provinces of China were found bearing eight species of fungal pathogens. Of those, six were aphid-specific Entomophthorales dominated in individual cases by Pandora neoaphidis, which occurs globally but has no resting spores discovered to date. Secondly, infected alates were confirmed to be able to fly for hours, to initiate colonies on plants after flight and to transmit fungal infection to their offspring in a laboratory experiment, in which 238 Sitobion avenae alates were individually flown in a computer-monitoring flight mill system after exposure to a spore shower of P. neoaphidis and then allowed to colonize host plants.

  1. Something To Rely On : The Influence of Stable and Fleeting Drivers on Moral Behavior

    NARCIS (Netherlands)

    G.G. van Houwelingen (Gijs)

    2015-01-01

    markdownabstract__Abstract__ In virtually any situation we are bound to encounter short-lived influences that lure us to act in a certain way. The influence of such ‘fleeting drivers’ may or may not be in line our long-term goals and commitments (‘stable drivers’). Moral behaviour in particular

  2. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

    Science.gov (United States)

    Gaya, Mauro; Barral, Patricia; Burbage, Marianne; Aggarwal, Shweta; Montaner, Beatriz; Warren Navia, Andrew; Aid, Malika; Tsui, Carlson; Maldonado, Paula; Nair, Usha; Ghneim, Khader; Fallon, Padraic G; Sekaly, Rafick-Pierre; Barouch, Dan H; Shalek, Alex K; Bruckbauer, Andreas; Strid, Jessica; Batista, Facundo D

    2018-01-25

    B cells constitute an essential line of defense from pathogenic infections through the generation of class-switched antibody-secreting cells (ASCs) in germinal centers. Although this process is known to be regulated by follicular helper T (TfH) cells, the mechanism by which B cells initially seed germinal center reactions remains elusive. We found that NKT cells, a population of innate-like T lymphocytes, are critical for the induction of B cell immunity upon viral infection. The positioning of NKT cells at the interfollicular areas of lymph nodes facilitates both their direct priming by resident macrophages and the localized delivery of innate signals to antigen-experienced B cells. Indeed, NKT cells secrete an early wave of IL-4 and constitute up to 70% of the total IL-4-producing cells during the initial stages of infection. Importantly, the requirement of this innate immunity arm appears to be evolutionarily conserved because early NKT and IL-4 gene signatures also positively correlate with the levels of neutralizing antibodies in Zika-virus-infected macaques. In conclusion, our data support a model wherein a pre-TfH wave of IL-4 secreted by interfollicular NKT cells triggers the seeding of germinal center cells and serves as an innate link between viral infection and B cell immunity. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Resting lymphocyte transduction with measles virus glycoprotein pseudotyped lentiviral vectors relies on CD46 and SLAM

    International Nuclear Information System (INIS)

    Zhou Qi; Schneider, Irene C.; Gallet, Manuela; Kneissl, Sabrina; Buchholz, Christian J.

    2011-01-01

    The measles virus (MV) glycoproteins hemagglutinin (H) and fusion (F) were recently shown to mediate transduction of resting lymphocytes by lentiviral vectors. MV vaccine strains use CD46 or signaling lymphocyte activation molecule (SLAM) as receptor for cell entry. A panel of H protein mutants derived from vaccine strain or wild-type MVs that lost or gained CD46 or SLAM receptor usage were investigated for their ability to mediate gene transfer into unstimulated T lymphocytes. The results demonstrate that CD46 is sufficient for efficient vector particle association with unstimulated lymphocytes. For stable gene transfer into these cells, however, both MV receptors were found to be essential.

  4. Relying on Your Own Best Judgment: Imputing Values to Missing Information in Decision Making.

    Science.gov (United States)

    Johnson, Richard D.; And Others

    Processes involved in making estimates of the value of missing information that could help in a decision making process were studied. Hypothetical purchases of ground beef were selected for the study as such purchases have the desirable property of quantifying both the price and quality. A total of 150 students at the University of Iowa rated the…

  5. Permissive and instructive anterior patterning rely on mRNA localization in the wasp embryo.

    Science.gov (United States)

    Brent, Ava E; Yucel, Gozde; Small, Stephen; Desplan, Claude

    2007-03-30

    The long-germ mode of embryogenesis, in which segments arise simultaneously along the anteriorposterior axis, has evolved several times in different lineages of the holometabolous, or fully metamorphosing, insects. Drosophila's long-germ fate map is established largely by the activity of the dipteran-specific Bicoid (Bcd) morphogen gradient, which operates both instructively and permissively to accomplish anterior patterning. By contrast, all nondipteran long-germ insects must achieve anterior patterning independently of bcd. We show that bcd's permissive function is mimicked in the wasp by a maternal repression system in which anterior localization of the wasp ortholog of giant represses anterior expression of the trunk gap genes so that head and thorax can properly form.

  6. Enabling Eco-Friendly Choices by Relying on the Proportional-Thinking Heuristic

    Directory of Open Access Journals (Sweden)

    Cleotilde Gonzalez

    2013-01-01

    Full Text Available Ecological (eco taxes are promising mechanisms to enable eco-friendly decisions, but few people prefer them. In this study, we present a way in which eco-tax options may be communicated to general public to encourage their payment. Our implementation (called “information presentation” takes advantage of the non-linear relationship between eco-tax payments and CO2 emissions and the human reliance on the proportional-thinking heuristic. According to the proportional-thinking heuristic, people are likely to prefer a small eco-tax increase and judge larger eco-tax increases to cause proportionally greater CO2 emissions reductions. In an online study, participants were asked to choose between eco-tax increases in two problems: In one, a smaller eco-tax increase resulted in greater CO2 emissions reduction, while in the other, a smaller tax increase resulted in lesser CO2 emissions reduction. Although the larger eco-tax increase did not reduce CO2 emissions the most, across both problems, people judged larger eco-tax increases to cause proportionally greater reductions in CO2 emissions and preferred smaller tax increases. Thus, eco-tax policies would benefit by presenting information in terms of eco-tax increases, such that smaller eco-tax increases (which are more attractive and are likely to be chosen by people cause greater CO2 emissions reductions.

  7. High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center.

    Science.gov (United States)

    Baños-Mateos, Soledad; van Roon, Anne-Marie M; Lang, Ulla F; Maslen, Sarah L; Skehel, J Mark; Lamers, Meindert H

    2017-10-11

    High-fidelity DNA replication depends on a proofreading 3'-5' exonuclease that is associated with the replicative DNA polymerase. The replicative DNA polymerase DnaE1 from the major pathogen Mycobacterium tuberculosis (Mtb) uses its intrinsic PHP-exonuclease that is distinct from the canonical DEDD exonucleases found in the Escherichia coli and eukaryotic replisomes. The mechanism of the PHP-exonuclease is not known. Here, we present the crystal structure of the Mtb DnaE1 polymerase. The PHP-exonuclease has a trinuclear zinc center, coordinated by nine conserved residues. Cryo-EM analysis reveals the entry path of the primer strand in the PHP-exonuclease active site. Furthermore, the PHP-exonuclease shows a striking similarity to E. coli endonuclease IV, which provides clues regarding the mechanism of action. Altogether, this work provides important insights into the PHP-exonuclease and reveals unique properties that make it an attractive target for novel anti-mycobacterial drugs.The polymerase and histidinol phosphatase (PHP) domain in the DNA polymerase DnaE1 is essential for mycobacterial high-fidelity DNA replication. Here, the authors determine the DnaE1 crystal structure, which reveals the PHP-exonuclease mechanism that can be exploited for antibiotic development.

  8. Dog and human inflammatory bowel disease rely on overlapping yet distinct dysbiosis networks.

    Science.gov (United States)

    Vázquez-Baeza, Yoshiki; Hyde, Embriette R; Suchodolski, Jan S; Knight, Rob

    2016-10-03

    Inflammatory bowel disease (IBD) is an autoimmune condition that is difficult to diagnose, and animal models of this disease have questionable human relevance 1 . Here, we show that the dysbiosis network underlying IBD in dogs differs from that in humans, with some bacteria such as Fusobacterium switching roles between the two species (as Bacteroides fragilis switches roles between humans and mice) 2 . For example, a dysbiosis index trained on humans fails when applied to dogs, but a dog-specific dysbiosis index achieves high correlations with the overall dog microbial community diversity patterns. In addition, a random forest classifier trained on dog-specific samples achieves high discriminatory power, even when using stool samples rather than the mucosal biopsies required for high discriminatory power in humans 2 . These relationships were not detected in previously published dog IBD data sets due to their limited sample size and statistical power 3 . Taken together, these results reveal the need to train host-specific dysbiosis networks and point the way towards a generalized understanding of IBD across different mammalian models.

  9. Cochrane and its prospects in Bosnia and Herzegovina: Relying on Cochrane Croatia.

    Science.gov (United States)

    Mahmić-Kaknjo, Mersiha; Puljak, Livia; Markotić, Filipa; Fidahić, Mahir; Muhamedagić, Lejla; Zakarija-Grković, Irena

    2015-01-01

    In this article we describe Cochrane and its products: Cochrane systematic reviews (CSRs) and other Cochrane evidence. Cochrane is a unique, international, non-profit organisation that offers health care providers, health care consumers and other decision makers unbiased and highly reliable information on health, which is pivotal for conscientious and responsible decision making in overall healthcare. Cochrane offers the highest ranked evidence in Evidence Based Medicine (EBM)--systematic reviews. Currently, CSRs are freely available in BH, and therefore, they ought to be widely used, and understood. We will present the new Cochrane Strategy to 2020, which was the main topic of the 6th Croatian Cochrane Symposium (CroCoS), as well as explore prospects for spreading Cochrane activities to Bosnia and Herzegovina (BH), through collaboration with Cochrane Croatia. BH has no officially organized Cochrane activity, as yet. We hope that this article will raise awareness about Cochrane in BH, help promote its activities, and deepen the existing collaboration with Cochrane Croatia. There are already some changes being introduced concerning Cochrane--at least, in one half, the Federation of BH (FBH). Two documents symbolising official recognition of policy changes towards Cochrane have recently been published in the Official Gazette of FBH. Since founding a BH Cochrane Branch would be costly and difficult to achieve in a complicated environment, such as the one we have, BH could use the good will, experience, knowledge, and translated educational, training and web materials of Cochrane Croatia, particularly given the language similarities, to promote evidence based medicine in BH. Copyright © 2015 by Academy of Sciences and Arts of Bosnia and Herzegovina.

  10. New Departure from Nucleate Boiling model relying on first principle energy balance at the boiling surface

    Science.gov (United States)

    Demarly, Etienne; Baglietto, Emilio

    2017-11-01

    Predictions of Departure from Nucleate Boiling have been a longstanding challenge when designing heat exchangers such as boilers or nuclear reactors. Many mechanistic models have been postulated over more than 50 years in order to explain this phenomenon but none is able to predict accurately the conditions which trigger the sudden change of heat transfer mode. This work aims at demonstrating the pertinence of a new approach for detecting DNB by leveraging recent experimental insights. The new model proposed departs from all the previous models by making the DNB inception come from an energy balance instability at the heating surface rather than a hydrodynamic instability of the bubbly layer above the surface (Zuber, 1959). The main idea is to modulate the amount of heat flux being exchanged via the nucleate boiling mechanism by the wetted area fraction on the surface, thus allowing a completely automatic trigger of DNB that doesn't require any parameter prescription. This approach is implemented as a surrogate model in MATLAB in order to validate the principles of the model in a simple and controlled geometry. Good agreement is found with the experimental data leveraged from the MIT Flow Boiling at various flow regimes. Consortium for Advanced Simulation of Light Water Reactors (CASL).

  11. Viroids: from genotype to phenotype just relying on RNA sequence and structural motifs

    Directory of Open Access Journals (Sweden)

    Ricardo eFlores

    2012-06-01

    Full Text Available As a consequence of two unique physical properties, small size and circularity, viroid RNAs do not code for proteins and thus depend on RNA sequence/structural motifs for interacting with host proteins that mediate their invasion, replication, spread, and circumvention of defensive barriers. Viroid genomes fold up on themselves adopting collapsed secondary structures wherein stretches of nucleotides stabilized by Watson-Crick pairs are flanked by apparently unstructured loops. However, compelling data show that they are instead stabilized by alternative non-canonical pairs and that specific loops in the rod-like secondary structure, characteristic of Potato spindle tuber viroid and most other members of the family Pospiviroidae, are critical for replication and systemic trafficking. In contrast, rather than folding into a rod-like secondary structure, most members of the family Avsunvioidae adopt multibranched conformations occasionally stabilized by kissing loop interactions critical for viroid viability in vivo. Besides these most stable secondary structures, viroid RNAs alternatively adopt during replication transient metastable conformations containing elements of local higher-order structure, prominent among which are the hammerhead ribozymes catalyzing a key replicative step in the family Avsunvioidae, and certain conserved hairpins that also mediate replication steps in the family Pospiviroidae. Therefore, different RNA structures ⎯either global or local ⎯ determine different functions, thus highlighting the need for in-depth structural studies on viroid RNAs.

  12. Self-awareness in neurodegenerative disease relies on neural structures mediating reward-driven attention.

    Science.gov (United States)

    Shany-Ur, Tal; Lin, Nancy; Rosen, Howard J; Sollberger, Marc; Miller, Bruce L; Rankin, Katherine P

    2014-08-01

    Accurate self-awareness is essential for adapting one's tasks and goals to one's actual abilities. Patients with neurodegenerative diseases, particularly those with right frontal involvement, often present with poor self-awareness of their functional limitations that may exacerbate their already jeopardized decision-making and behaviour. We studied the structural neuroanatomical basis for impaired self-awareness among patients with neurodegenerative disease and healthy older adults. One hundred and twenty-four participants (78 patients with neurodegenerative diseases including Alzheimer's disease, behavioural variant frontotemporal dementia, right-temporal frontotemporal dementia, semantic variant and non-fluent variant primary progressive aphasia, and 46 healthy controls) described themselves on the Patient Competency Rating Scale, rating observable functioning across four domains (daily living activities, cognitive, emotional control, interpersonal). All participants underwent structural magnetic resonance imaging. Informants also described subjects' functioning on the same scale. Self-awareness was measured by comparing self and informant ratings. Group differences in discrepancy scores were analysed using general linear models, controlling for age, sex and disease severity. Compared with controls, patients with behavioural variant frontotemporal dementia overestimated their functioning in all domains, patients with Alzheimer's disease overestimated cognitive and emotional functioning, patients with right-temporal frontotemporal dementia overestimated interpersonal functioning, and patients with non-fluent aphasia overestimated emotional and interpersonal functioning. Patients with semantic variant aphasia did not overestimate functioning on any domain. To examine the neuroanatomic correlates of impaired self-awareness, discrepancy scores were correlated with brain volume using voxel-based morphometry. To identify the unique neural correlates of overlooking versus exaggerating deficits, overestimation and underestimation scores were analysed separately, controlling for age, sex, total intracranial volume and extent of actual functional decline. Atrophy related to overestimating one's functioning included bilateral, right greater than left frontal and subcortical regions, including dorsal superior and middle frontal gyri, lateral and medial orbitofrontal gyri, right anterior insula, putamen, thalamus, and caudate, and midbrain and pons. Thus, our patients' tendency to under-represent their functional decline was related to degeneration of domain-general dorsal frontal regions involved in attention, as well as orbitofrontal and subcortical regions likely involved in assigning a reward value to self-related processing and maintaining accurate self-knowledge. The anatomic correlates of underestimation (right rostral anterior cingulate cortex, uncorrected significance level) were distinct from overestimation and had a substantially smaller effect size. This suggests that underestimation or 'tarnishing' may be influenced by non-structural neurobiological and sociocultural factors, and should not be considered to be on a continuum with overestimation or 'polishing' of functional capacity, which appears to be more directly mediated by neural circuit dysfunction. © The Author (2014). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. A data model for simulation models relying on spatio-temporal urban data

    OpenAIRE

    Langlois , G ,; Tourre , Vincent; Servières , Myriam; Gervais , G ,; Gesquière , Gilles

    2016-01-01

    International audience; To understand the complexity of modern cities and anticipate their expansion, experts from various fields conceive simulation models that can be very different. Those simulation models work with a variety of data with their own organization. Furthermore, because the urban objects are studied in the context of the evolution of a city or urban area, they carry temporal and spatial information. In this paper, we present the base classes of a common data model robust and f...

  14. Defense Headquarters: Geographic Combatant Commands Rely on Subordinate Commands for Mission Management and Execution

    Science.gov (United States)

    2016-06-30

    Committee announced his priorities which included a review of DOD’s organization and lines of authority established as a result of the Goldwater...See enclosure). This report formally transmits an updated briefing and communicates the final results of our work. To describe DOD’s allocation of...its mission to manage the detention facility at Guantanamo Bay, Cuba to Joint Task Force Guantanamo (JTF-GTMO). However, the extent to which each

  15. Relying on fin erosion to identify hatchery-reared brown trout in a Tennessee river

    Science.gov (United States)

    Meerbeek, Jonathan R.; Bettoli, Phillip William

    2012-01-01

    Hatchery-induced fin erosion can be used to identify recently stocked catchable-size brown trout Salmo trutta during annual surveys to qualitatively estimate contributions to a fishery. However, little is known about the longevity of this mark and its effectiveness as a short-term (≤ 1 year) mass-marking technique. We evaluated hatchery-induced pectoral fin erosion as a mass-marking technique for short-term stocking evaluations by stocking microtagged brown trout in a tailwater and repeatedly sampling those fish to observe and measure their pectoral fins. At Dale Hollow National Fish Hatchery, 99.1% (228 of 230) of microtagged brown trout in outdoor concrete raceways had eroded pectoral fins 1 d prior to stocking. Between 34 and 68 microtagged and 26-35 wild brown trout were collected during eight subsequent electrofishing samples. In a blind test based on visual examination of pectoral fins at up to 322 d poststocking, one observer correctly identified 91.7% to 100.0% (mean of 96.9%) of microtagged brown trout prior to checking for microtags. In the laboratory, pectoral fin length and width measurements were recorded to statistically compare the fin measurements of wild and microtagged hatchery brown trout. With only one exception, all pectoral fin measurements on each date averaged significantly larger for wild trout than for microtagged brown trout. Based on the number of pectoral fin measurements falling below 95% prediction intervals, 93.7% (148 of 158) of microtagged trout were correctly identified as hatchery fish based on regression models up to 160 d poststocking. Only 72.2% (70 of 97) of microtagged trout were identified correctly after 160 d based on pectoral fin measurements and the regression models. We concluded that visual examination of pectoral fin erosion was a very effective way to identify stocked brown trout for up to 322 d poststocking.

  16. Urinary concentration does not exclusively rely on plasma vasopressin. A study between genders

    DEFF Research Database (Denmark)

    Graugaard-Jensen, Charlotte; Hvistendahl, Gitte M; Frøkiaer, Jørgen

    2014-01-01

    AimWe investigated the influence of gender on the diurnal regulation of urine production with special focus on vasopressin, oxytocin and prostaglandin E2. MethodsFifteen young women in mid-follicular phase and 22 young men (20-33years) were included. All participants underwent a 24-h circadian in...

  17. To what extent does organic farming rely on nutrient inflows from conventional farming?

    International Nuclear Information System (INIS)

    Nowak, Benjamin; Nesme, Thomas; Pellerin, Sylvain; David, Christophe

    2013-01-01

    Organic farming is increasingly recognized as a prototype for sustainable agriculture. Its guidelines ban the use of artificial fertilizers. However, organic farms may import nutrients from conventional farming through material exchanges. In this study, we aimed at estimating the magnitude of these flows through the quantification of nitrogen, phosphorus and potassium inflows from conventional farming to organic farming. Material inflows and outflows were collected for two cropping years on 63 farms. The farms were located in three French agricultural districts distributed over a gradient of farming activity defined by both the stocking rate and the ratio of the farm area under arable crops. Our results showed that on average, inflows from conventional farming were 23%, 73% and 53% for nitrogen, phosphorus and potassium, respectively. These inflows were strongly determined by the farm production systems. However, for farms similar in terms of production systems, the inflows also depended on the local context, such as the proximity of organic livestock farms: the reliance of organic farming on conventional farming was lower in mixed than in specialized districts. These results highlight the necessity to quantify the contribution of nutrient inflows from conventional farming when assessing organic farming and development scenarios. (letter)

  18. Potential for bias in epidemiologic studies that rely on glass-based retrospective assessment of radon

    International Nuclear Information System (INIS)

    Weinberg, C.R.

    1995-01-01

    Retrospective assessment of exposure to radon remains the greatest challenge in epidemiologic efforts to assess lung cancer risk associated with residential exposure. An innovative technique based on measurement of α-emitting, long-lived daughters embedded by recoil into household glass may one day provide improved radon dosimetry. Particulate air pollution is known, however, to retard the plate-out of radon daughters. This would be expected to result in a differential effect on dosimetry, where the calibration curve relating the actual historical radon exposure to the remaining α-activity in the glass would be different in historically smoky and nonsmoky environments. The resulting open-quotes measurement confoundingclose quotes can distort inferences about the effect of radon and can also produce spurious evidence for synergism between radon exposure and cigarette smoking. 18 refs., 4 figs

  19. Figure-ground segregation can rely on differences in motion direction.

    Science.gov (United States)

    Kandil, Farid I; Fahle, Manfred

    2004-12-01

    If the elements within a figure move synchronously while those in the surround move at a different time, the figure is easily segregated from the surround and thus perceived. Lee and Blake (1999) [Visual form created solely from temporal structure. Science, 284, 1165-1168] demonstrated that this figure-ground separation may be based not only on time differences between motion onsets, but also on the differences between reversals of motion direction. However, Farid and Adelson (2001) [Synchrony does not promote grouping in temporally structured displays. Nature Neuroscience, 4, 875-876] argued that figure-ground segregation in the motion-reversal experiment might have been based on a contrast artefact and concluded that (a)synchrony as such was 'not responsible for the perception of form in these or earlier displays'. Here, we present experiments that avoid contrast artefacts but still produce figure-ground segregation based on purely temporal cues. Our results show that subjects can segregate figure from ground even though being unable to use motion reversals as such. Subjects detect the figure when either (i) motion stops (leading to contrast artefacts), or (ii) motion directions differ between figure and ground. Segregation requires minimum delays of about 15 ms. We argue that whatever the underlying cues and mechanisms, a second stage beyond motion detection is required to globally compare the outputs of local motion detectors and to segregate figure from ground. Since analogous changes take place in both figure and ground in rapid succession, this second stage has to detect the asynchrony with high temporal precision.

  20. Can we rely on predicted basal metabolic rate in chronic pancreatitis outpatients?

    Science.gov (United States)

    Olesen, Søren Schou; Holst, Mette; Køhler, Marianne; Drewes, Asbjørn Mohr; Rasmussen, Henrik Højgaard

    2015-04-01

    Malnutrition is a common complication to chronic pancreatitis (CP) and many patients need nutritional support. An accurate estimation of the basal metabolic rate (BMR) is essential when appropriate nutritional support is to be initiated, but in the clinical settings BMR is cumbersome to measure. We therefore investigated whether BMR can be reliable predicted from a standard formula (the Harris-Benedict equation) in CP outpatients. Twenty-eight patients with clinical stable CP and no current alcohol abuse were enrolled. Patients were stratified according to nutritional risk using the Nutrition Risk Screening 2002 system. Body composition was estimated using bioelectrical impedance. BMR was measured using indirect calorimetry and predicted using the Harris-Benedict equation based on anthropometric data. The average predicted BMR was 1371 ± 216 kcal/day compared to an average measured BMR of 1399 ± 231 kcal/day (P = 0.4). The corresponding limits of agreement were -347 to 290 kcal/day. Twenty-two patients (79%) had a measured BMR between 85 and 115% of the predicted BMR. When analysing patients stratified according to nutritional risk profiles, no differences between predicted and measured BMR were evident for any of the risk profile subgroups (all P > 0.2). The BMR was correlated to fat free mass determined by bioelectrical impedance (rho = 0.55; P = 0.003), while no effect modification was seen from nutritional risk stratification in a linear regression analysis (P = 0.4). The Harris-Benedict equation reliable predicts the measured BMR in four out of five clinical stable CP outpatients with no current alcohol abuse. Copyright © 2015 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.

  1. DIGITAL BOOKS RELY ON SOCIAL READING TO FIND NEW SUCCESS PROPOSALS AND FORMATS

    Directory of Open Access Journals (Sweden)

    Berta García Orosa

    2016-07-01

    Full Text Available Digital reading development has reached turning point. In view of the recent data, the edition of electronic books has dropped for the second consecutive year in 2014, while paper books production has increased (MECD, 2015. The last report from the Fundación Telefónica (2015 points out that six out ten Spanish people prefer printed books instead of the digital ones. This article presents the symptoms of a possible change of tendency in digital books. There is a need for a new digital ecosystem of digital texts production and reception. Its major focus should be the social reading, understood as a space for reception, interpretation, and creation.

  2. Can gingival crevicular blood be relied upon for assessment of blood glucose level?

    Science.gov (United States)

    Dwivedi, Shivani; Verma, Sharmila J; Shah, Monali; Jain, Kapil

    2014-11-01

    Diabetes mellitus (DM) is undiagnosed in approximately half of the patients actually suffering from the disease. In addition, the prevalence of DM is more than twice as high as in patients with periodontitis when compared to periodontally healthy subjects. Thus, a high number of patients with periodontitis may have undiagnosed DM. The purpose of the present study was to evaluate whether blood oozing from a gingival crevice during routine periodontal examination can be used for determining glucose levels. Observational cross-sectional studies were carried out in 75 patients (43 males and 32 females) with chronic periodontitis who were divided into two groups: Group I and Group II, respectively. Blood oozing from the gingival crevices of anterior teeth following periodontal probing was collected with the stick of glucose self-monitoring device, and the blood glucose levels were measured. At the same time, finger-prick blood was taken for glucometric analysis and subsequent readings were recorded. The patient's blood glucose values ranged from 74 to 256 mg/dl. The comparison between gingival crevicular blood and finger-prick blood showed a very strong correlation, with a t value of 3.97 (at P value = 0.001). The data from this study has shown that GCB collected during diagnostic periodontal examination can be an excellent source of blood for glucometric analysis.

  3. The achievement gap: Should we rely on SAT scores to tell us anything about it?

    Directory of Open Access Journals (Sweden)

    Dale Whittington

    2004-04-01

    Full Text Available Increasing numbers of students taking the SAT have declined to identify their race/ethnicity. I examined the impact of non-respondents on the validity of reported racial/ethnic differences and year-to-year changes in test performance. Using an analysis reported by Wainer (1988 and SAT data from 1996 to 2003, I confirmed Wainer’s findings that non-respondents prevent accurate estimations of group differences based on SAT data. I then explored the impact of College Board press release information on news reports about the achievement gap. I found frequent reports of racial/ethnic differences in SAT scores and year-to-year changes in scores but negligible consideration of non-respondents. Press releases and media reports should include information about non-respondents and their impact on accuracy of reported differences based on race/ethnicity.

  4. Place preference and vocal learning rely on distinct reinforcers in songbirds.

    Science.gov (United States)

    Murdoch, Don; Chen, Ruidong; Goldberg, Jesse H

    2018-04-30

    In reinforcement learning (RL) agents are typically tasked with maximizing a single objective function such as reward. But it remains poorly understood how agents might pursue distinct objectives at once. In machines, multiobjective RL can be achieved by dividing a single agent into multiple sub-agents, each of which is shaped by agent-specific reinforcement, but it remains unknown if animals adopt this strategy. Here we use songbirds to test if navigation and singing, two behaviors with distinct objectives, can be differentially reinforced. We demonstrate that strobe flashes aversively condition place preference but not song syllables. Brief noise bursts aversively condition song syllables but positively reinforce place preference. Thus distinct behavior-generating systems, or agencies, within a single animal can be shaped by correspondingly distinct reinforcement signals. Our findings suggest that spatially segregated vocal circuits can solve a credit assignment problem associated with multiobjective learning.

  5. Why science? to know, to understand, and to rely on results

    CERN Document Server

    Newton, Roger G

    2012-01-01

    This book aims to describe, for readers uneducated in science, the development of humanity's desire to know and understand the world around us through the various stages of its development to the present, when science is almost universally recognized - at least in the Western world - as the most reliable way of knowing. The book describes the history of the large-scale exploration of the surface of the earth by sea, beginning with the Vikings and the Chinese, and of the unknown interiors of the American and African continents by foot and horseback. After the invention of the telescope, visual exploration of the surfaces of the Moon and Mars were made possible, and finally a visit to the Moon. The book then turns to our legacy from the ancient Greeks of wanting to understand rather than just know, and why the scientific way of understanding is valued. For concreteness, it relates the lives and accomplishments of six great scientists, four from the nineteenth century and two from the twentieth. Finally, the boo...

  6. Short-term Internet search using makes people rely on search engines when facing unknown issues.

    Science.gov (United States)

    Wang, Yifan; Wu, Lingdan; Luo, Liang; Zhang, Yifen; Dong, Guangheng

    2017-01-01

    The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers to 40 unusual questions, remember the answers and recall them in the scanner. Un-learned questions were randomly presented at the recalling stage in order to elicited search impulse. Comparing to the pre-test, subjects in the post-test reported higher impulse to use search engines to answer un-learned questions. Consistently, subjects showed higher brain activations in dorsolateral prefrontal cortex and anterior cingulate cortex in the post-test than in the pre-test. In addition, there were significant positive correlations self-reported search impulse and brain responses in the frontal areas. The results suggest that a simple six-day's Internet search training can make people dependent on the search tools when facing unknown issues. People are easily dependent on the Internet search engines.

  7. Short-term Internet search using makes people rely on search engines when facing unknown issues.

    Directory of Open Access Journals (Sweden)

    Yifan Wang

    Full Text Available The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers to 40 unusual questions, remember the answers and recall them in the scanner. Un-learned questions were randomly presented at the recalling stage in order to elicited search impulse. Comparing to the pre-test, subjects in the post-test reported higher impulse to use search engines to answer un-learned questions. Consistently, subjects showed higher brain activations in dorsolateral prefrontal cortex and anterior cingulate cortex in the post-test than in the pre-test. In addition, there were significant positive correlations self-reported search impulse and brain responses in the frontal areas. The results suggest that a simple six-day's Internet search training can make people dependent on the search tools when facing unknown issues. People are easily dependent on the Internet search engines.

  8. Conflict detection and resolution rely on a combination of common and distinct cognitive control networks.

    Science.gov (United States)

    Li, Qi; Yang, Guochun; Li, Zhenghan; Qi, Yanyan; Cole, Michael W; Liu, Xun

    2017-12-01

    Cognitive control can be activated by stimulus-stimulus (S-S) and stimulus-response (S-R) conflicts. However, whether cognitive control is domain-general or domain-specific remains unclear. To deepen the understanding of the functional organization of cognitive control networks, we conducted activation likelihood estimation (ALE) from 111 neuroimaging studies to examine brain activation in conflict-related tasks. We observed that fronto-parietal and cingulo-opercular networks were commonly engaged by S-S and S-R conflicts, showing a domain-general pattern. In addition, S-S conflicts specifically activated distinct brain regions to a greater degree. These regions were implicated in the processing of the semantic-relevant attribute, including the inferior frontal cortex (IFC), superior parietal cortex (SPC), superior occipital cortex (SOC), and right anterior cingulate cortex (ACC). By contrast, S-R conflicts specifically activated the left thalamus, middle frontal cortex (MFC), and right SPC, which were associated with detecting response conflict and orienting spatial attention. These findings suggest that conflict detection and resolution involve a combination of domain-general and domain-specific cognitive control mechanisms. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. JET ({sup 3}He)-D scenarios relying on RF heating: survey of selected recent experiments

    Energy Technology Data Exchange (ETDEWEB)

    Van Eester, D; Lerche, E; Andrew, Y; Biewer, T M; Casati, A; Crombe, K; De la Luna, E; Ericsson, G; Felton, R; Giacomelli, L; Giroud, C; Hawkes, N; Hellesen, C; Hjalmarsson, A; Joffrin, E; Kaellne, J; Kiptily, V; Lomas, P; Mantica, P; Marinoni, A [JET-EFDA Culham Science Centre, Abingdon, OX14 3DB (United Kingdom)] (and others)

    2009-04-15

    Recent JET experiments have been devoted to the study of ({sup 3}He)-D plasmas involving radio frequency (RF) heating. This paper starts by discussing the RF heating efficiency theoretically expected in such plasmas, covering both relevant aspects of wave and of particle dynamics. Then it gives a concise summary of the main conclusions drawn from recent experiments that were either focusing on studying RF heating physics aspects or that were adopting RF heating as a tool to study plasma behavior. Depending on the minority concentration chosen, different physical phenomena are observed. At very low concentration (X[{sup 3}He] < 1%), energetic tails are formed which trigger MHD activity and result in loss of fast particles. Alfven cascades were observed and gamma ray tomography indirectly shows the impact of sawtooth crashes on the fast particle orbits. Low concentration (X[{sup 3}He] < 10%) favors minority heating while for X[{sup 3}He] >> 10% electron mode conversion damping becomes dominant. Evidence for the Fuchs et al standing wave effect (Fuchs et al 1995 Phys. Plasmas 2 1637-47) on the absorption is presented. RF induced deuterium tails were observed in mode conversion experiments with large X[{sup 3}He] ({approx}18%). As tentative modeling shows, the formation of these tails can be explained as a consequence of wave power absorption by neutral beam particles that efficiently interact with the waves well away from the cold D cyclotron resonance position as a result of their substantial Doppler shift. As both ion and electron RF power deposition profiles in ({sup 3}He)-D plasmas are fairly narrow-giving rise to localized heat sources-the RF heating method is an ideal tool for performing transport studies. Various of the experiments discussed here were done in plasmas with internal transport barriers (ITBs). ITBs are identified as regions with locally reduced diffusivity, where poloidal spinning up of the plasma is observed. The present know-how on the role of RF heating for impurity transport is also briefly summarized.

  10. CERN birthplace of the World Wide Web relies on Day's Communiqué

    CERN Multimedia

    2001-01-01

    In close collaboration with CERN, Day developed a platform to enable interested research groups to integrate disparate data sources and to author content based on individual needs... Days Virtual Repository - The ContentBus - allows the integration of data sources and provides for the presentation of all work processes at CERN, from pure text to complex research data. With data procured in real time from the original location, it avoids data redundancy, insufficient scalability and unneccessary allocation of resources for constant data reconcilliation and additional database licenses.

  11. Brucella Intracellular Life Relies on the Transmembrane Protein CD98 Heavy Chain.

    Science.gov (United States)

    Keriel, Anne; Botella, Eric; Estrach, Soline; Bragagnolo, Gabriel; Vergunst, Annette C; Feral, Chloe C; O'Callaghan, David

    2015-06-01

    Brucella are intracellular bacterial pathogens that use a type IV secretion system (T4SS) to escape host defenses and create a niche in which they can multiply. Although the importance of Brucella T4SS is clear, little is known about its interactions with host cell structures. In this study, we identified the eukaryotic protein CD98hc as a partner for Brucella T4SS subunit VirB2. This transmembrane glycoprotein is involved in amino acid transport, modulation of integrin signaling, and cell-to-cell fusion. Knockdown of CD98hc expression in HeLa cells demonstrated that it is essential for Brucella infection. Using knockout dermal fibroblasts, we confirmed its role for Brucella but found that it is not required for Salmonella infection. CD98hc transiently accumulates around the bacteria during the early phases of infection and is required for both optimal bacterial uptake and intracellular multiplication of Brucella. These results provide new insights into the complex interplay between Brucella and its host. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  12. Efficient peroxydisulfate activation process not relying on sulfate radical generation for water pollutant degradation.

    Science.gov (United States)

    Zhang, Tao; Chen, Yin; Wang, Yuru; Le Roux, Julien; Yang, Yang; Croué, Jean-Philippe

    2014-05-20

    Peroxydisulfate (PDS) is an appealing oxidant for contaminated groundwater and toxic industrial wastewaters. Activation of PDS is necessary for application because of its low reactivity. Present activation processes always generate sulfate radicals as actual oxidants which unselectively oxidize organics and halide anions reducing oxidation capacity of PDS and producing toxic halogenated products. Here we report that copper oxide (CuO) can efficiently activate PDS under mild conditions without producing sulfate radicals. The PDS/CuO coupled process is most efficient at neutral pH for decomposing a model compound, 2,4-dichlorophenol (2,4-DCP). In a continuous-flow reaction with an empty-bed contact time of 0.55 min, over 90% of 2,4-DCP (initially 20 μM) and 90% of adsorbable organic chlorine (AOCl) can be removed at the PDS/2,4-DCP molar ratio of 1 and 4, respectively. Based on kinetic study and surface characterization, PDS is proposed to be first activated by CuO through outer-sphere interaction, the rate-limiting step, followed by a rapid reaction with 2,4-DCP present in the solution. In the presence of ubiquitous chloride ions in groundwater/industrial wastewater, the PDS/CuO oxidation shows significant advantages over sulfate radical oxidation by achieving much higher 2,4-DCP degradation capacity and avoiding the formation of highly chlorinated degradation products. This work provides a new way of PDS activation for contaminant removal.

  13. refining of scintillation detector signals relying on interpolated wavelets on a FPGA prototype

    International Nuclear Information System (INIS)

    Aboshosha, A.; Sayed, M.; Ashour, M.; Safwat, A.

    2010-01-01

    in this article, a signal processing core based on field programmable gate arrays (FPGAs) is developed for processing of scintillation detector signals. this core is implemented to apply the forward wavelet transfrom and interpolation technique. the main purpose of that is to de-noise, compress and reconstruct these signals by which the processing speed and storage will be optimized. moreover, this technique gives us all important features of the acquired signals such as counting, shaping and pulse height. A new contribution of our framework arises from employing the interpolation techniques to reconstruct the signal where the mother wavelet and details are not required. The hardware design is implemented using hardware description language (HDL) and is implemented practically on the FPGA. The performance of the design has been tested in simulation mode on Model sim benchmark and in real time mode on XC2S 50 spartan- II FPGA.

  14. Ants learn to rely on more informative attributes during decision-making.

    Science.gov (United States)

    Sasaki, Takao; Pratt, Stephen C

    2013-01-01

    Evolutionary theory predicts that animals act to maximize their fitness when choosing among a set of options, such as what to eat or where to live. Making the best choice is challenging when options vary in multiple attributes, and animals have evolved a variety of heuristics to simplify the task. Many of these involve ranking or weighting attributes according to their importance. Because the importance of attributes can vary across time and place, animals might benefit by adjusting weights accordingly. Here, we show that colonies of the ant Temnothorax rugatulus use their experience during nest site selection to increase weights on more informative nest attributes. These ants choose their rock crevice nests on the basis of multiple features. After exposure to an environment where only one attribute differentiated options, colonies increased their reliance on this attribute relative to a second attribute. Although many species show experience-based changes in selectivity based on a single feature, this is the first evidence in animals for adaptive changes in the weighting of multiple attributes. These results show that animal collectives, like individuals, change decision-making strategies according to experience. We discuss how these colony-level changes might emerge from individual behaviour.

  15. Early Career Researchers Demand Full-text and Rely on Google to Find Scholarly Sources

    Directory of Open Access Journals (Sweden)

    Richard Hayman

    2017-12-01

    Full Text Available A Review of: Nicholas, D., Boukacem-Zeghmouri, C., Rodríguez-Bravo, B., Xu, J., Watkinson, A., Abrizah, A., Herman, E., & Świgoń, M. (2017. Where and how early career researchers find scholarly information. Learned Publishing, 30(1, 19-29. http://dx.doi.org/10.1002/leap.1087 Abstract Objective – To examine the attitudes and information behaviours of early career researchers (ECRs when locating scholarly information. Design – Qualitative longitudinal study. Setting – Research participants from the United Kingdom, United States of America, China, France, Malaysia, Poland, and Spain. Subjects – A total 116 participants from various disciplines, aged 35 and younger, who were holding or had previously held a research position, but not in a tenured position. All participants held a doctorate or were in the process of earning one. Methods – Using structured interviews of 60-90 minutes, researchers asked 60 questions of each participant via face-to-face, Skype, or telephone interviews. The interview format and questions were formed via focus groups. Main Results – As part of a longitudinal project, results reported are limited to the first year of the study, and focused on three primary questions identified by the authors: where do ECRs find scholarly information, whether they use their smartphones to locate and read scholarly information, and what social media do they use to find scholarly information. Researchers describe how ECRs themselves interpreted the phrase scholarly information to primarily mean journal articles, while the researchers themselves had a much expanded definition to include professional and “scholarly contacts, ideas, and data” (p. 22. This research shows that Google and Google Scholar are widely used by ECRs for locating scholarly information regardless of discipline, language, or geography. Their analysis by country points to currency and the combined breadth-and-depth search experience that Google provides as prime reasons for the popularity of Google and Google Scholar. Of particular interest is the popularity and use of Google Scholar in China, where it is officially blocked but accessed by ECRs via proxy services. Other general indexes, such as Web of Science and Scopus, are also popular but not universally used by ECRs, and regional differences again point to pros and cons of these services. Some specialized services are emphasized, including regional tools such as the China National Knowledge Infrastructure, as well as certain broad disciplinary resources, such as PubMed for its coverage of sciences and biomedical information. Researchers report that ECRs participating in this study were less concerned about how they gained access to full-text scholarly information, only that they could access full-text sources. In particular, ECRs do not take much notice of libraries and their platforms, seemingly unaware of the steps libraries take to acquire and ensure access to scholarly information, while viewing physical libraries themselves primarily as study spaces for undergraduate students and not places for the ECR to visit or work. While ECRs occasionally acknowledge library portals and login interfaces, researchers found that these participants mostly ignored these, and that they found discovery services to be confusing or difficult. Concerning social media use, participants identified 11 different platforms used but only ResearchGate was mentioned and used by participants from all seven countries represented. Social media tends to be used directly for keeping track of research trends and opinions and also the work specific researchers are publishing, and indirectly when referred to sites such as ResearchGate to find full-text of a specific article. Facebook, Twitter, and LinkedIn are used occasionally or moderately, but not universally. Researchers highlight regional differences of social media use in China, where ECRs are more likely to connect with other researchers and receive notifications when those researchers publish. The study reports limited information ECRs’ use of smartphones for information seeking. About half of ECR participants reported use of their smartphone for discovering scholarly sources. The advantage smartphones provide includes near-ubiquitous Internet access and therefore the ability to access scholarly materials on the go, though ECRs are less likely to download or read full-text articles via their smartphones. The rate of adoption of smartphone use for scholarly materials varies by country. Conclusion – Early career researchers access scholarly information in a wide variety of ways, with Google and Google Scholar as the preferred starting location, and with social media also proving useful. Ease-of-use and full-text availability are paramount concerns; the spread of open access materials helps fuel the availability of materials, and Google makes these easy to find. Though physical libraries are perceived to be of limited use, the digital access they provide to full-text scholarly sources is still vital even if ECRs do not make the connection between having that important access and the fact that libraries act as buyers and providers of access

  16. Antropogenní transformace reliéfu v oblasti dolu Jeroným

    Czech Academy of Sciences Publication Activity Database

    Kirchner, Karel; Roštínský, Pavel

    2011-01-01

    Roč. 18, č. 1 (2011), s. 92-98 ISSN 1803-1447 R&D Projects: GA ČR GA105/09/0089 Institutional research plan: CEZ:AV0Z30860518 Keywords : geomorphology * anthropogenic transformation * Slavkovský les Forest Subject RIV: DE - Earth Magnetism, Geodesy, Geography www.caag.cz

  17. Neuroprotective effects of 17β-estradiol rely on estrogen receptor membrane initiated signals

    Directory of Open Access Journals (Sweden)

    Marco eFiocchetti

    2012-04-01

    Full Text Available 17β-estradiol (E2 exerts protective effects in the central nervous system besides its crucial role in many physiological and pathological events. E2 effects are not restricted to the brain areas related with the control of the reproductive function, but rather are widespread throughout the developing and the adult brain. E2 actions are mediated by estrogen receptors (i.e., ERα and ERβ belonging to the nuclear receptor super family. As members of the ligand-regulated transcription factor family, the actions of ERs in the brain were thought to mediate only the E2 long-term transcriptional effects. However, a growing body of evidence has emerged indicating the presence of rapid, membrane initiated E2 effects in the brain which result independent from ER transcriptional activities and involved in E2-induced neuroprotection. Aim of this review is to focus on the rapid effects of E2 in the brain taking into account the specific contribution of the signaling pathway of ERβ subtype in neuroprotective actions of E2.

  18. Skipping of Chinese characters does not rely on word-based processing.

    Science.gov (United States)

    Lin, Nan; Angele, Bernhard; Hua, Huimin; Shen, Wei; Zhou, Junyi; Li, Xingshan

    2018-02-01

    Previous eye-movement studies have indicated that people tend to skip extremely high-frequency words in sentence reading, such as "the" in English and "/de" in Chinese. Two alternative hypotheses have been proposed to explain how this frequent skipping happens in Chinese reading: one assumes that skipping happens when the preview has been fully identified at the word level (word-based skipping); the other assumes that skipping happens whenever the preview character is easy to identify regardless of whether lexical processing has been completed or not (character-based skipping). Using the gaze-contingent display change paradigm, we examined the two hypotheses by substituting the preview of the third character of a four-character Chinese word with the high-frequency Chinese character "/de", which should disrupt the ongoing word-level processing. The character-based skipping hypothesis predicts that this manipulation will enhance the skipping probability of the target character (i.e., the third character of the target word), because the character "/de" has much higher character frequency than the original character. The word-based skipping hypothesis instead predicts a reduction of the skipping probability of the target character because the presence of the character "/de" is lexically infelicitous at word level. The results supported the character-based skipping hypothesis, indicating that in Chinese reading the decision of skipping a character can be made before integrating it into a word.

  19. Efficient peroxydisulfate activation process not relying on sulfate radical generation for water pollutant degradation

    KAUST Repository

    Zhang, Tao

    2014-05-20

    Peroxydisulfate (PDS) is an appealing oxidant for contaminated groundwater and toxic industrial wastewaters. Activation of PDS is necessary for application because of its low reactivity. Present activation processes always generate sulfate radicals as actual oxidants which unselectively oxidize organics and halide anions reducing oxidation capacity of PDS and producing toxic halogenated products. Here we report that copper oxide (CuO) can efficiently activate PDS under mild conditions without producing sulfate radicals. The PDS/CuO coupled process is most efficient at neutral pH for decomposing a model compound, 2,4-dichlorophenol (2,4-DCP). In a continuous-flow reaction with an empty-bed contact time of 0.55 min, over 90% of 2,4-DCP (initially 20 μM) and 90% of adsorbable organic chlorine (AOCl) can be removed at the PDS/2,4-DCP molar ratio of 1 and 4, respectively. Based on kinetic study and surface characterization, PDS is proposed to be first activated by CuO through outer-sphere interaction, the rate-limiting step, followed by a rapid reaction with 2,4-DCP present in the solution. In the presence of ubiquitous chloride ions in groundwater/industrial wastewater, the PDS/CuO oxidation shows significant advantages over sulfate radical oxidation by achieving much higher 2,4-DCP degradation capacity and avoiding the formation of highly chlorinated degradation products. This work provides a new way of PDS activation for contaminant removal. © 2014 American Chemical Society.

  20. PERiMENSTRUAL DiSTRES VE HEMiŞiRELiK YAKLAŞIMI

    OpenAIRE

    KIZILKAYA, Nezihe

    2015-01-01

    Kadm populasyonunun % 70'inden \\'Ogu perimenstrual distres §ikayetlerinin en az bir ya da daha fazlasmdan etkilenmektedir. Perimenstrual distres  §ikayetlerinin azaltihnas1 ya da Onlen1nesi iyin stres azalt1na, egzersiz, diyet, egiti1n ve da.n1 rnanhk bile§enlerinden olu§an <;ok boyutlu bio-psiko-sosyal bir yakla§1m oneril mektedir. Hem§ireler perimenstrual distres §ikayetlerinin onlenmesi ya da tedavisinde <;ok onemli bir role sahiptirler.

  1. Metabolic imidacloprid resistance in the brown planthopper, Nilaparvata lugens, relies on multiple P450 enzymes.

    Science.gov (United States)

    Zhang, Yixi; Yang, Yuanxue; Sun, Huahua; Liu, Zewen

    2016-12-01

    Target insensitivity contributing to imidacloprid resistance in Nilaparvata lugens has been reported to occur either through point mutations or quantitative change in nicotinic acetylcholine receptors (nAChRs). However, the metabolic resistance, especially the enhanced detoxification by P450 enzymes, is the major mechanism in fields. From one field-originated N. lugens population, an imidacloprid resistant strain G25 and a susceptible counterpart S25 were obtained to analyze putative roles of P450s in imidacloprid resistance. Compared to S25, over-expression of twelve P450 genes was observed in G25, with ratios above 5.0-fold for CYP6AY1, CYP6ER1, CYP6CS1, CYP6CW1, CYP4CE1 and CYP425B1. RNAi against these genes in vivo and recombinant tests on the corresponding proteins in vitro revealed that four P450s, CYP6AY1, CYP6ER1, CYP4CE1 and CYP6CW1, played important roles in imidacloprid resistance. The importance of the four P450s was not equal at different stages of resistance development based on their over-expression levels, among which CYP6ER1 was important at all stages, and that the others might only contribute at certain stages. The results indicated that, to completely reflect roles of P450s in insecticide resistances, their over-expression in resistant individuals, expression changes at the stages of resistance development, and catalytic activities against insecticides should be considered. In this study, multiple P450s, CYP6AY1, CYP6ER1, CYP4CE1 and CYP6CW1, have proven to be important in imidacloprid resistance. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Atmea launches Atmea1 the mid-sized generation 3+ PWR you can rely on

    International Nuclear Information System (INIS)

    2008-01-01

    ATMEA, a daughter company of AREVA NP and Mitsubishi Heavy Industries, is developing and will supply ATMEA1, the most advanced 1100 MWe PWR plant with the combination of the unique set of competence and experience of its parent companies. This folder presents the ATMEA1 reactor main features. (J.S.)

  3. Property Mix Heterogeneity and Market Cycles: How Much Can We Rely on Median-Price Indices?

    Directory of Open Access Journals (Sweden)

    Odilon Ricardo da Hora Gonçalves Fernandes Costa

    2017-05-01

    Full Text Available Objective. Understand in which types of location median-price indices could provide reasonable estimates of rent growth. As far as our research allows, the market-based measures developed througout this study are the first to emphasize office properties in Brazil using an hedonic framework.Methodology. Create appraisal-based indices of rent growth using median-price and hedonic-based techniques for two regions with different degrees of property mix heterogeneity and compare their behavior overtime.Findings. Volatility in median-price measures is larger than hedonic-based measures in market peaks and throughs due to different weighting of high and low-tier properties overtime. This result is stronger in the location with higher property mix heterogeneity and, consequently, exacerbates market cycles in this region.  Limitations. We do not find statistically significant differences between the measures considered. Nevertheless, we do not consider whether this similarity would hold when using transactional-based data.    Value. Our results suggest that researchers, policy makers and investors need to take into account the “undesired fluctuation” of median-price measures when interpreting such indices.  

  4. Nature does not rely on long-lived electronic quantum coherence for photosynthetic energy transfer

    Science.gov (United States)

    Duan, Hong-Guang; Prokhorenko, Valentyn I.; Cogdell, Richard J.; Ashraf, Khuram; Stevens, Amy L.; Thorwart, Michael; Miller, R. J. Dwayne

    2017-08-01

    During the first steps of photosynthesis, the energy of impinging solar photons is transformed into electronic excitation energy of the light-harvesting biomolecular complexes. The subsequent energy transfer to the reaction center is commonly rationalized in terms of excitons moving on a grid of biomolecular chromophores on typical timescales Olson protein, in which interference oscillatory signals up to 1.5 ps were reported and interpreted as direct evidence of exceptionally long-lived electronic quantum coherence. Here, we show that the optical 2D photon echo spectra of this complex at ambient temperature in aqueous solution do not provide evidence of any long-lived electronic quantum coherence, but confirm the orthodox view of rapidly decaying electronic quantum coherence on a timescale of 60 fs. Our results can be considered as generic and give no hint that electronic quantum coherence plays any biofunctional role in real photoactive biomolecular complexes. Because in this structurally well-defined protein the distances between bacteriochlorophylls are comparable to those of other light-harvesting complexes, we anticipate that this finding is general and directly applies to even larger photoactive biomolecular complexes.

  5. You can’t rely on color, yet we all do 2.0 (Manuscript only)

    NARCIS (Netherlands)

    Nes, van F.L.; Eschbach, R.; Marcu, G.G.; Rizzi, A.

    2013-01-01

    Everybody views and uses color from early childhood onwards. But this magnificent property of all objects around us turns out to be elusive if you try to specify it and communicate it to another person. Also, people often don’t know what effects color may have under different conditions. However,

  6. SEE ME ROAR: Self-determination Enhanced Engagement for Math Education Relying On Augmented Reality

    NARCIS (Netherlands)

    Li, J.; van der Spek, E.D.; Hu, J.; Feijs, L.M.G.

    2017-01-01

    Contemporary primary school students generally spend a lot of time playing digital games, but may be less interested in their schoolwork, such as learning mathematics. Mathematics includes many abstract concepts that can be difficult to grasp for some students. Augmented reality as a technology

  7. Early Career Researchers Demand Full-text and Rely on Google to Find Scholarly Sources

    OpenAIRE

    Richard Hayman

    2017-01-01

    A Review of: Nicholas, D., Boukacem-Zeghmouri, C., Rodríguez-Bravo, B., Xu, J., Watkinson, A., Abrizah, A., Herman, E., & Świgoń, M. (2017). Where and how early career researchers find scholarly information. Learned Publishing, 30(1), 19-29. http://dx.doi.org/10.1002/leap.1087 Abstract Objective – To examine the attitudes and information behaviours of early career researchers (ECRs) when locating scholarly information. Design – Qualitative longitudinal study. Setting – R...

  8. Efficient peroxydisulfate activation process not relying on sulfate radical generation for water pollutant degradation

    KAUST Repository

    Zhang, Tao; Chen, Yin; Wang, Yuru; Le Roux, Julien; Yang, Yang; Croue, Jean-Philippe

    2014-01-01

    Peroxydisulfate (PDS) is an appealing oxidant for contaminated groundwater and toxic industrial wastewaters. Activation of PDS is necessary for application because of its low reactivity. Present activation processes always generate sulfate radicals

  9. Wild hummingbirds rely on landmarks not geometry when learning an array of flowers.

    Science.gov (United States)

    Hurly, T Andrew; Fox, Thomas A O; Zwueste, Danielle M; Healy, Susan D

    2014-09-01

    Rats, birds or fish trained to find a reward in one corner of a small enclosure tend to learn the location of the reward using both nearby visual features and the geometric relationships of corners and walls. Because these studies are conducted under laboratory and thereby unnatural conditions, we sought to determine whether wild, free-living rufous hummingbirds (Selasphorus rufus) learning a single reward location within a rectangular array of flowers would similarly employ both nearby visual landmarks and the geometric relationships of the array. Once subjects had learned the location of the reward, we used test probes in which one or two experimental landmarks were moved or removed in order to reveal how the birds remembered the reward location. The hummingbirds showed no evidence that they used the geometry of the rectangular array of flowers to remember the reward. Rather, they used our experimental landmarks, and possibly nearby, natural landmarks, to orient and navigate to the reward. We believe this to be the first test of the use of rectangular geometry by wild animals, and we recommend further studies be conducted in ecologically relevant conditions in order to help determine how and when animals form complex geometric representations of their local environments.

  10. Mask induction despite circuit obstruction: an unrecognized hazard of relying on automated machine check technology.

    Science.gov (United States)

    Yang, Kamie K; Lewis, Ian H

    2014-06-15

    Various equipment malfunctions of anesthesia gas delivery systems have been previously reported. Our profession increasingly uses technology as a means to prevent these errors. We report a case of a near-total anesthesia circuit obstruction that went undetected before the induction of anesthesia despite the use of automated machine check technology. This case highlights that automated machine check modules can fail to detect severe equipment failure and demonstrates how, even in this era of expanding technology, manual checks still remain essential components of safe care.

  11. The assessment of nanofluid in a Von Karman flow with temperature relied viscosity

    Directory of Open Access Journals (Sweden)

    Anum Tanveer

    2018-06-01

    Full Text Available This work endeavor to study the heat and mass transfer viscous nanofluid features in a Von Karman flow invoking the variable viscosity mechanism. Moreover, we have extended our study in view of heat generation and uniform suction effects. The flow triggering non-linear partial differential equations are inscribed in the non-dimensional form by manipulating suitable transformations. The resulting non-linear ordinary differential equations are solved numerically via implicit finite difference scheme in conjecture with the Newton’s linearization scheme afterwards. The sought solutions are plotted graphically to present comparison between MATLAB routine bvp4c and implicit finite difference schemes. Impact of different parameters on the concentration/temperature/velocity profiles are highlighted. Further Nusselt number, skin friction and Sherwood number characteristics are discussed for better exposition. Keywords: Von Karman flow, Variable viscosity, Heat generation, Suction, Nanofluid, Implicit finite difference scheme, Bvp4c

  12. Relatos de experiencias: Trabajar con entrevistas, historia oral ¿Quién narra y para quién? Sobre la (in corrección del cuestionario y otros cuestiones metodológicas

    Directory of Open Access Journals (Sweden)

    Patricia Graciela Sepúlveda

    2016-07-01

    Full Text Available En este artículo se realiza un trabajo reflexivo respecto de las tensiones presentes en la producción de un texto conversacional producto de entrevistas de historia oral y pretende analizar evasivas, subtextos y tropos que los entrevistados utilizan para filtrar, resistir o manejar en la interacción. Se inscribe en una investigación que combinó la perspectiva de género y memoria, y que buscaba analizar un período de la historia reciente de nuestro país a través de los testimonios de sus protagonistas. Se hace hincapié, a través de fragmentos que funcionan como disparadores, en el trabajo interpretativo de relatos sobre experiencias. Relatos que nos permiten acceder a tensiones, temporalidades, significados, agencia y subjetividad.

  13. La ecuación "más privado, menos estatal": quiénes ganan y quiénes pierden. El caso del servicio de transporte público en el Gran Buenos Aires

    Directory of Open Access Journals (Sweden)

    Susana Kralich

    2002-09-01

    Full Text Available El artículo pretende demostrar, particularmente para el caso del transporte público metropolitano, cómo la transformación de las estructuras estatales, siguiendo los dictados de las nuevas formas de acumulación flexible, impactan en perjuicio de crecientes contingentes de población. Cautivos del sistema de transporte masivo, operado hoy en su totalidad por empresas privadas; desprotegidos por un Estado debilitado y permeable al poder de lobby de los concesionarios, ven desdibujarse hasta casi desaparecer el concepto de servicio público, cuya esencia implica la garantía de universalidad de las prestaciones. Presentamos la medición de la accesibilidad departamental, relacionando oferta de transporte masivo con población residente y niveles de pobreza. El análisis de su distribución socioespacial explicaría las incidencias con que los costos de transporte gravitan sobre los estratos más desprotegidos, los que por sus características y localización, no conforman mercados rentables para la operatoria privadaThis article pretends to demostrate, specially about the case of the metropolitan public transport system, how the changes to the state structures, resulting from the new flexible ownership patterns, impact to the detriment of increasing groups of captive users. The mass transport system, now operated solely by private operators, without sufficient regulatory protection, shows the gradual disappearance of public service concept, since weakness state is more receptive to the lobbying power of the concessionaires. With that objective, we present the results of our accessibility departmental measurement, by comparing the amount of public transport service offer with the number of residents and poor levels. The analysis would explain a socio-spatial pattern of higher costs of public transport in areas where the most vulnerable population groups are located due to the lack of profitable markets to be served

  14. Clinical audits: who does control what? European guide lines;Audits cliniques: qui controle quoi? Lignes directrices europeennes

    Energy Technology Data Exchange (ETDEWEB)

    Jarvinen, H. [Ingenieur es Sciences, Expert en chef pour l' Utilisation des Rayonnements Ionisants A des fins medicales, Autorite de Surete Nucleaire et de Radioprotection (STUK), Helsinki (Finland)

    2009-12-15

    The E.C. directive 97/43/EURATOM (M.E.D.-directive) introduced the concept of Clinical Audit for the assessment of medical radiological practices (diagnostic radiology, nuclear medicine and radiotherapy). The European Commission started in June 2007 a special project to review in detail the status of implementation of Clinical audits in Member States and to prepare European Guidance on Clinical Audits for diagnostic radiology, nuclear medicine and radiotherapy. The purpose of this E.C. project is to provide clear and comprehensive information and guidance on the procedures and criteria for clinical audits in all radiological practices, in order to improve the implementation of Article 6.4 of the M.E.D.-directive. The guidance should be flexible and enable the member States to adopt the model of clinical audit with respect to their national legislation and administrative provisions. By definition, clinical audit is a systematic examination or review of medical radiological procedures. It seeks to improve the quality and the outcome of patient care through structured review whereby radiological practices, procedures and results are examined against agreed standards for good medical radiological procedures. Modifications of the practices are implemented where indicated and new standards applied if necessary. The general objectives of clinical audit should be: to improve the quality of patient care, to promote the effective use of resources, to enhance the provision and organization of clinical services, to further professional education and training. Clinical audits must be at the same time internal (set by the management of the department) and external (set by external auditors at the department). It must not be confused with other evaluation activities such inspections, accreditation or quality system certifications. Clinical audits should address structure, process and outcome such the unit mission, quality assurance, dosimetry and treatments follow-up. The recent guideline on clinical audit published by the European Commission wants to support the principles and implementation of clinical audit and provides a general framework for the development of national clinical audits that are viable. (N.C.)

  15. ¿Quiénes sostienen la alimentación en Ecuador?: un derecho aún no resuelto

    OpenAIRE

    Aguinaga Barragán, Margarita; Flores Chamba, Enith

    2013-01-01

    Hablar del derecho a la alimentación (DaA) va más allá de la medición de los índices de nutrición que reflejarían de esta manera la situación alimentaria en el país, implica el cumplimiento de las condiciones necesarias en el entorno de los seres humanos para que este derecho pueda ser ejercido a cabalidad. Según las Directrices Voluntarias del Derecho a la Alimentación establecidas por la Organización de las Naciones Unidas para la Alimentación y la Agricultura (FAO), impli...

  16. Ecce Agnus Dei, qui tollit peccata mundi. Sobre los símbolos de Jesucristo en la Edad Media

    Directory of Open Access Journals (Sweden)

    Torres Jiménez, Raquel

    2013-06-01

    Full Text Available The article deals with the symbolic meanings of Agnus Dei in the Middle Ages, its uses, reception and evolution, from the perspective of both religious and cultural history. It makes use of the analysis of the Church Fathers’ texts, Christian medieval literature, theological discourse, biblical exegesis in the medieval context, iconography, objects from churches, as well as the analysis of liturgy and mysticism. The text gives priority to an integral view of the symbol, which, beyond moral analogies, is able to explain the whole history of salvation: Agnus Dei evokes how the salvific facts of the past become present in the Eucharist and extend triumphantly into the future.El artículo trata de los significados simbólicos del Agnus Dei en la Edad Media, sus usos, recepciones y evolución, desde la perspectiva de la historia religiosa y de la historia cultural. Se sirve del análisis de textos de los Padres de la Iglesia, literatura cristiana medieval, discursos teológicos, exégesis bíblica en el contexto medieval, iconografía, objetos de iglesias, liturgia, mística. Se privilegia la visión integral de este símbolo, que, más allá de analogías morales, tiene capacidad para explicar toda la historia de la salvación: el Agnus Dei evoca cómo los hechos salvíficos del pasado se hacen presentes en la eucaristía y se proyectan triunfalmente hacia el futuro.

  17. Y a-t-il quelqu'un qui écoute les Haïtiens ? | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    12 oct. 2010 ... Project in Haiti to make medical care more efficient through technology. "Rebuild better" has become a mantra in Haiti as the nation struggles to recover from the devastating January earthquake. View moreProject in Haiti to make medical care more efficient through technology ...

  18. Biodiversité et santé : Tuons-nous les plantes qui peuvent nous guérir

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 févr. 2011 ... En outre, le déboisement et la désertification, réduisant tant la qualité du bois que la quantité, ont eu des effets néfastes sur la demande, tandis que la ... La popularité des guérisseurs traditionnels et de leurs remèdes repose en partie sur le faible coût des services et des médicaments, affirme Messanvi ...

  19. Société du savoir arabe - qui représente le monde arabe en ligne ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Visionnement du film Little Gandhi —The Lost Truth of the Syrian Uprising à New York. La mission du Canada auprès des Nations Unies projettera des extraits du film Little Gandhi, un documentaire sur la Syrie subventionné par le CDRI. Voir davantageVisionnement du film Little Gandhi —The Lost Truth of the Syrian ...

  20. Martine Monacelli et Michel Prum. Ces hommes qui épousèrent la cause des femmes

    Directory of Open Access Journals (Sweden)

    Frédéric REGARD

    2010-09-01

    Full Text Available Cet ouvrage collectif compte dix chapitres, consacrés chacun à l’un des « pionniers » hommes du féminisme. Les militants ou sympathisants sont  pour certains très célèbres, mais pour d’autres pratiquement inconnus, William Godwin, John Stuart Mill, William Thompson et Edward Carpenter côtoyant William Johnson Fox, George Lansbury, Israel Zangwill, Frederick Pethic-Lawrence, Frederick Billington-Greig ou encore Victor Duval. Une bibliographie sélective complète l’ouvrage, malheureusement dépou...

  1. ¿Quién puede ser autor de un artículo científico?

    Directory of Open Access Journals (Sweden)

    Marco González T

    2011-04-01

    Full Text Available De acuerdo con el diccionario de la Real Academia Española (1, autor tiene cinco acepciones, pero la que se acerca a los intereses del presente escrito reza así: “Persona que ha producido alguna obra científica, literaria o artística”. No obstante, en el ámbito científico y académico esta definición puede ser más amplia, compleja y aun alcanzar diferentes connotaciones si se tienen en cuenta algunas reflexiones generales sobre la materia y no menos importante cuando se tiene presente; como debería ser, las razones éticas para firmar como autor o coautor de un artículo. Estas consideraciones son las intrínsecas de la investigación y que se generan dentro de un grupo en particular, que se preocupa, por ejemplo, en ser el primero en publicar artículos sobre un tema específico. Otros, con otra óptica, podrían tener interés en ostentar el mayor número de artículos publicados en una determinada área del conocimiento.

  2. L'efficacité des interventions à caractère électronique pour ce qui est ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'étude portera sur de petits exploitants du Bénin, du Ghana, du Kenya, de Madagascar, du Malawi et d'Ouganda, où de telles interventions sont déjà déployées. Dans chaque pays, les chercheurs collecteront des données à la fois quantitatives et qualitatives sur 340 agriculteurs, répartis en fonction de leur utilisation des ...

  3. ¿Quiénes son ellos?: un estudio psicoanalítico sobre El proceso de Kafka

    OpenAIRE

    Martins, Francisco; Universidad de Brasilia (Brasil)

    1999-01-01

    El texto presenta el análisis y las reflexiones desarrollados en el Laboratorio de Psicopatología y Psicoanálisis de la Universidad de Brasilia, acerca de la cuestión de "él" (" ellos') en El proceso, de Franz Kafka, y en un caso de delirio de persecución. Fue especialmente investigado el estatuto del pronombre "él" en la paranoia. El trabajo muestra que la comprensión de "él" (" ellos') es un elemento esencial para la elucidación de la cuestión de la extrañeza en la psicosis y de la construc...

  4. Impact, en ce qui a trait à l'économie et à la santé, des politiques ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cette recherche évaluera l'effet des politiques fiscales et législatives sur l'état nutritionnel des Sud-Africains et recommandera d'importantes modifications aux politiques. La plus récente étude nationale sur la charge de morbidité (2000) a mesuré l'impact des MNT à la lumière de divers indicateurs tels que le coût financier, ...

  5. “Bendig tu…qui fis me fenna”: donne, libri e letteratura nel Medioevo giudeo-provenzale

    OpenAIRE

    Erica Baricci

    2014-01-01

    In the Medieval Hebrew Literature, we have no evidence about women as authors, except for Dunash ibn Labrat’s wife (X cent.) and Qasmuna bat Isma’il (XII cent.). Women were not "silent" at all in the Middle Ages, but the feminine way to compose texts at that time was oral, being made in the native Jewish-Languages, while Hebrew – known almost only by men - was the language of the written Literature. In this essay we will deal with the (self-)representation of women in the Judae...

  6. “Bendig tu…qui fis me fenna”: donne, libri e letteratura nel Medioevo giudeo-provenzale

    Directory of Open Access Journals (Sweden)

    Erica Baricci

    2014-04-01

    Women were not "silent" at all in the Middle Ages, but the feminine way to compose texts at that time was oral, being made in the native Jewish-Languages, while Hebrew – known almost only by men - was the language of the written Literature. In this essay we will deal with the (self-representation of women in the Judaeo-Provencal medieval literary corpus. First, we will analyze some texts, explicitly composed for women, in order to understand the feminine perspective and literary liking as a public. Second, we will deal with an example of women literary creativeness, i.e. a particular Jewish blessing, transmitted in three extant Jewish prayerbooks (XV century, which recites: “Bless you God, for I was born a woman”. This probably refers to a local tradition of Provencal Jewish women who created it during the Middle Ages.

  7. Qu'est-ce qui détermine l'accès aux TIC aux Philippines ? | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    8 févr. 2011 ... Le guide dépasse cependant l'anecdote et les conseils pour traiter de la question ... par la population à ces instruments et ses capacités à les utiliser ». .... sont les possibilités qu'elles servent d'outils pour le développement.

  8. L'efficacité des interventions à caractère électronique pour ce qui est ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Journal supplement features 10 years of West African health systems research. In the wake of the devastating Ebola virus outbreak in 2014, increased attention has been paid to West Africa's poorly functioning health systems. View moreJournal supplement features 10 years of West African health systems research.

  9. ¿A quién beneficia el comercio paralelo de medicamentos en la Unión Europea?

    Directory of Open Access Journals (Sweden)

    Joan Costa-Font

    2009-01-01

    Full Text Available El comercio paralelo constituye un movimiento legal (arbitraje comercial de productos de un país donde éstos se han puesto en circulación a otro país sin la autorización y la garantía del que posee los derechos de propiedad intelectual del producto. Este fenómeno se deriva de la aplicación del principio de subsidiariedad que lleva asociado la existencia de diferentes sistemas de regulación de precios y el de libre movilidad de bienes. En este artículo examinamos las tendencias de precios y penetración de medicamentos paralelamente importados respecto al precio del producto en el país de destino (beneficios de una mayor competencia en 2002. En segundo lugar, establecemos una descomposición empírica de los efectos del comercio paralelo de medicamentos en los tres mercados principales de la Unión Europea en los diferentes agentes de la cadena del medicamento. Los resultados no siguieren pruebas de un efecto competitivo del comercio paralelo. Por otra parte, se observa que los principales beneficiarios son los propios importadores paralelos en la medida que el comercio paralelo genera ahorros muy limitados en la factura de los sistemas de salud, que difícilmente superan los perjuicios en la innovación farmacéutica.

  10. Ces poisons qui tuent dans les entreprises Un cancer sur dix serait d'origine professionnelle chez les hommes

    CERN Multimedia

    Noël, Florence

    2005-01-01

    Geneva launched an expertise of all the buildings built before 1991. Ill, a former employee of CERN testifies. On their side, several thousands of victims of asbestos demonstrated on Saturday in Paris

  11. Le silence, ce cri qui résonne dans l’écriture de Viviane Forrester

    Directory of Open Access Journals (Sweden)

    Amelia Peral Crespo

    2015-11-01

    Full Text Available The Holocaust Literature is tied to Silence from its beginning as the writing to silence. Write about the Holocaust and relate the experiences lived in first person or transmit them to the coming generations means leaving the silence which, for years, was the ideal refuge. This research focuses on the literary production of Viviane Forrester. The different expressions of silence that characterize her writings are analyzed. Silence is the cry that underlies in the most profound of the human being that return from the concentration camps, as Lazarus from the dead. It is a silence that grows to a cry because Forrester’s writing, almost in parallel to the fragmentary writing of Blanchot, an-nounces livre à venir, expressing the cry in silence without the ending of the word

  12. "Qué pertenece a quién": Procesos de patrimonialización y Pueblos Originarios en Patagonia

    Directory of Open Access Journals (Sweden)

    Carolina Crespo

    2005-07-01

    Full Text Available Mientras en el pasado, el relato histórico y la identidad nacional/provincial se configuró en base a la negación y/o rechazo de la diferencia y se camufló la desigualdad bajo la apelación a una unidad cultural, particular y homogénea como lo fue el criollismo; hoy los restos arqueológicos del pasado indígena son re-categorizados en la legislación de la provincia de Río Negro como patrimonio cultural de la misma. Frente a la complejidad que reviste tal situación, me propongo analizar las ambigüedades y contradicciones que se desprenden de esta clasificación en el ámbito legislativo provincial y los conflictos que se tejen en torno a esta activación patrimonial entre los agentes estatales y el pueblo mapuche. Intento demostrar que estas contradicciones son producto de -y moldean- la dinámica que ha adquirido en años recientes la relación entre el pueblo mapuche y los agentes estatales, a la vez que de ciertas directrices internacionales.In the past, the national/provincial&'s history and identity was shaped by refusing and/or rejecting differences, while inequity was hidden by claiming for a particular and homogeneous cultural unity: &"the criollismo&". Nowadays, the archaeological rests of indigenous past are re-categorized in Rio Negro`s legislation as a province`s cultural heritage. Considering the complexity of these circumstances, the purpose of this article is (to analyse the contradictions and ambiguousness released by this classification at the legislative context and the conflicts that this heritage activation weaves between the state`s agents and mapuche`s people. I will try to demonstrate that this contradictions are the product of -and also provide- the relationship between mapuche`s people, state`s agents and certain international directrices in recent years.

  13. INNOVATION ET R-D DANS LES SERVICES : DES MODALITÉS ORIGINALES, QUI PEUVENT ENRICHIR LES CONCEPTIONS INDUSTRIELLES

    OpenAIRE

    Gadrey , Jean; Gallouj , Faïz; Lhuillery , Stéphane; Weinstein , Olivier

    1994-01-01

    International audience; Bien que les services soient largement majoritaires dans les grands agrégats économiques, ils ne représentent qu'une faible proportion des dépenses ou des effectifs de R-D des entreprises tels qu'ils sont évalués par les organismes nationaux et internationaux. Par ailleurs, les théories économiques de l'innovation tendent à négliger les services ou à considérer que l'innovation y est pour l'essentiel réduite à l'adoption d'innovations produites dans l'industrie. Dans c...

  14. L'INNOVATION DANS LES SERVICES : DES MODALITÉS ORIGINALES, QUI PEUVENT ENRICHIR LES CONCEPTIONS INDUSTRIELLES

    OpenAIRE

    Gadrey , Jean; Gallouj , Faïz; Weinstein , Olivier

    1995-01-01

    International audience; Bien qu'ils soient largement majoritaires dans les grands agrégats économiques, les théories économiques de l'innovation tendent à négliger les services ou à considérer que l'innovation y est pour l'essentiel réduite à l'adoption d'innovations produites dans l'industrie. Dans cette contribution, on conteste ces points de vue en examinant les trois questions suivantes -pourquoi l'innovation dans les services est-elle méconnue ou oubliée par ces théories? -quelles sont (...

  15. ¿Quién habla de las mujeres en las noticias donde ellas son las protagonistas?

    Directory of Open Access Journals (Sweden)

    Ana Tamarit

    2011-01-01

    Full Text Available Este artículo presenta un análisis de las fuentes que los periodistas utilizan en las informaciones donde las mujeres son protagonistas de las noticias. La investigación -cuantitativa y cualitativa- se ha realizado en los periódicos de ámbito nacional y local de Castilla y León. Con los resultados obtenidos observamos cómo en los periódicos las noticias que hablan de las mujeres en la mayoría de las ocasiones no se firman. Comprobamos cuáles son las fuentes más utilizadas para la elaboración de esas noticias y las diferentes formas de citar a la fuente cuando se trata de un hombre o de una mujer.

  16. La empresa troyana y la pregunta por el quién en el pensamiento de Hannah Arendt

    Directory of Open Access Journals (Sweden)

    Pinilla Cañadas, Scheherezade

    2016-06-01

    Full Text Available This article attempts to answer all those scholars who maintain that Hannah Arendt is a political thinker of Hellenic nostalgia. From such a perspective, it is easy to conclude not only that Arendt´s thought is irrelevant to contemporary concerns but that she is an elitist reactionary when it comes to assessing the prospects of representative democracies. It is to be considered here that this reading is wrong and one-sided, and that the major work upon which it is based, The Human Condition, needs to be studied in a nuanced way, as engaging in multiple complex dialogue with philosophic-political tradition. To this end, this paper begins by briefly explicating not at all her dependency upon Heidegger, but rather a “radical conversation” with him. This conversation, even when only partially explored, casts considerable light on Arendt´s entire philosophical project. Secondly, this paper supports the view that Homer offers an ideal vantage point from which to tackle what Miguel Abensour has called “a political conception of heroism.” More specifically, the thesis which is to be defended here is that Iliad, and particularly the catalogue of ships in Book 2, could be understood as the origin of the Arendtian account of plurality.Este artículo pretende dar respuesta a toda esa crítica que sostiene que Hannah Arendt es una pensadora política con nostalgia de la pólis. Desde esta perspectiva, no resulta muy difícil concluir, no sólo que el pensamiento de Arendt es irrelevante en relación con los problemas contemporáneos; sino que estamos ante una auténtica reaccionaria cuando se trata de analizar las grandes cuestiones de las democracias representativas. Aquí se entiende que esta lectura es errónea y parcial y también que la obra sobre la que dicha interpretación se articula, La condición humana, debe ser estudiada de un modo mucho más sutil; que pasaría por un diálogo múltiple y complejo con la tradición filosófico-política. A tal fin, se hace una breve exposición, no tanto de su dependencia con Heidegger, cuanto de su “conversación radical” con él. Esta conversación (si bien sólo se estudia parcialmente arroja mucha luz sobre el proyecto filosófico de Hannah Arendt en su conjunto. En segundo lugar, en este trabajo se postula que Homero ofrece una perspectiva inmejorable a la hora de analizar lo que Miguel Abensour ha denominado “una concepción política del heroísmo.” De manera más específica, la tesis que aquí se defiende es que la Ilíada, y particularmente el catálogo de las naves del Canto II, podrían ser interpretados como el origen del concepto arendtiano de pluralidad.

  17. The Use of Copper- 64 in the Investigation of Reaction Mechanisms of Enzymes, Particularly as Related to Food Processing; Emploi de Cuivre-64 dans l'Etude des Mecanismes de Reaction des Enzymes, Notamment en Ce Qui Concerne la Preparation des Denrees Alimentaires; ПРИМЕНЕНИЕ МЕДИ-64 ДЛЯ ИССЛЕДОВАНИЯ МЕХАНИЗМОВ ФЕРМЕНТАТИВНЫХ РЕАКЦИЙ, СВЯЗАННЫХ С ОБРАБОТКОЙ ПИЛИ; Empleo de Cobre-64 en el Estudio de los Mecanismos de Reacciones Enzima Ticas de Interes para la Elaboracion de Alimentos

    Energy Technology Data Exchange (ETDEWEB)

    Arthur, Jr., J. C.; McLemore, T. A. [Southern Regional Research Laboratory, New Orleans, LA (United States)

    1963-03-15

    The oxidative enzymes of plant tissues are often dormant or only slightly active during the resting state, becoming active on the injury of the tissue or on separation from the tissue. During food processing this results in an acceleration of the oxidation of the natural substrates and polymerization of the products, which discolour the tissue. Copper oxidases are the principal enzymes involved in catalysing these reactions. The activation of the enzyme also leads to its reaction inactivation. One of the causes of the phenomenon of reaction inactivation is the decrease in the effective concentration of the enzyme, probably by the removal or binding of its metal prosthetic group copper. By using copper- 64, in vitro, it was shown that, in a resting solution, cupric ion can complex and/or exchange with the copper of the enzyme and that, in oxidizing solutions, an additional amount of cupric ion can be complexed. Cu-o-quinone- type complexes have higher formation constants than Cu-p-quinone- type complexes. The amount of cupric ion complexed was decreased, if the ion was added in an oxidizing solution after the initiation of polymerization of the o-quinone type reaction products. The kinetics of the exchange and complexing processes for cupric ions with enzyme and reaction products are discussed mathematically. (author) [French] Les enzymes oxydants des tissus vegetaux sont souvent inactifs ou tres peu actifs a l'etat de repos et ne deviennent actifs qu'en cas de lesion du tissu ou lorsqu'ils sont separes de celui-ci. Lors de la preparation des denrees alimentaires, ce phenomene a pour effet d'accelerer l'oxydation des substrats naturels et de polymeriser les produits, ce qui donne lieu a une decoloration du tissu. Les oxydases de cuivre sont les principaux enzymes qui interviennent comme catalyseurs dans ces reactions. L'activation de l'enzyme entraine en outre une inhibition de la reaction qu'il subit. Une des causes de ce phenomene est la diminution de la

  18. Adaptability of the Saccharomyces cerevisiae yeasts to wine fermentation conditions relies on their strong ability to consume nitrogen

    Science.gov (United States)

    2018-01-01

    Saccharomyces cerevisiae strains are genetically diverse, largely as a result of human efforts to develop strains specifically adapted to various fermentation processes. These adaptive pressures from various ecological niches have generated behavioral differences among these strains, particularly in terms of their nitrogen consumption capacities. In this work, we characterize this phenotype by the specific quantity of nitrogen consumed under oenological fermentation conditions using a new approach. Indeed, unlike previous studies, our experiments were conducted in an environment containing excess nitrogen, eliminating the nitrogen limitation/starvation factor that is generally observed in fermentation processes. Using these conditions, we evaluated differences in the nitrogen consumption capacities for a set of five strains from diverse origins. The strains presented extremely different phenotypes and variations in their capacities to take up nitrogen from a wine fermentation environment. These variations reflect the differences in the nitrogen uptake capacities between wine and non-wine strains. Finally, the strains differed in their ability to adapt to the nitrogen composition of the environment, leading to variations in the cellular stress states, fermentation performances and the activity of the nitrogen sensing signaling pathway. PMID:29432462

  19. Developmental shaping of dendritic arbors in Drosophila relies on tightly regulated intra-neuronal activity of protein kinase A (PKA).

    Science.gov (United States)

    Copf, Tijana

    2014-09-15

    Dendrites develop morphologies characterized by multiple levels of complexity that involve neuron type specific dendritic length and particular spatial distribution. How this is developmentally regulated and in particular which signaling molecules are crucial in the process is still not understood. Using Drosophila class IV dendritic arborization (da) neurons we test in vivo the effects of cell-autonomous dose-dependent changes in the activity levels of the cAMP-dependent Protein Kinase A (PKA) on the formation of complex dendritic arbors. We find that genetic manipulations of the PKA activity levels affect profoundly the arbor complexity with strongest impact on distal branches. Both decreasing and increasing PKA activity result in a reduced complexity of the arbors, as reflected in decreased dendritic length and number of branching points, suggesting an inverted U-shape response to PKA. The phenotypes are accompanied by changes in organelle distribution: Golgi outposts and early endosomes in distal dendritic branches are reduced in PKA mutants. By using Rab5 dominant negative we find that PKA interacts genetically with the early endosomal pathway. We test if the possible relationship between PKA and organelles may be the result of phosphorylation of the microtubule motor dynein components or Rab5. We find that Drosophila cytoplasmic dynein components are direct PKA phosphorylation targets in vitro, but not in vivo, thus pointing to a different putative in vivo target. Our data argue that tightly controlled dose-dependent intra-neuronal PKA activity levels are critical in determining the dendritic arbor complexity, one of the possible ways being through the regulation of organelle distribution. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Self-control depletion in tufted capuchin monkeys (Sapajus spp.): does delay of gratification rely on a limited resource?

    Science.gov (United States)

    Petrillo, Francesca De; Micucci, Antonia; Gori, Emanuele; Truppa, Valentina; Ariely, Dan; Addessi, Elsa

    2015-01-01

    Self-control failure has enormous personal and societal consequences. One of the most debated models explaining why self-control breaks down is the Strength Model, according to which self-control depends on a limited resource. Either previous acts of self-control or taking part in highly demanding cognitive tasks have been shown to reduce self-control, possibly due to a reduction in blood glucose levels. However, several studies yielded negative findings, and recent meta-analyses questioned the robustness of the depletion effect in humans. We investigated, for the first time, whether the Strength Model applies to a non-human primate species, the tufted capuchin monkey. We tested five capuchins in a self-control task (the Accumulation task) in which food items were accumulated within individual's reach for as long as the subject refrained from taking them. We evaluated whether capuchins' performance decreases: (i) when tested before receiving their daily meal rather than after consuming it (Energy Depletion Experiment), and (ii) after being tested in two tasks with different levels of cognitive complexity (Cognitive Depletion Experiment). We also tested, in both experiments, how implementing self-control in each trial of the Accumulation task affected this capacity within each session and/or across consecutive sessions. Repeated acts of self-control in each trial of the Accumulation task progressively reduced this capacity within each session, as predicted by the Strength Model. However, neither experiencing a reduction in energy level nor taking part in a highly demanding cognitive task decreased performance in the subsequent Accumulation task. Thus, whereas capuchins seem to be vulnerable to within-session depletion effects, to other extents our findings are in line with the growing body of studies that failed to find a depletion effect in humans. Methodological issues potentially affecting the lack of depletion effects in capuchins are discussed.

  1. Catalytic ozonation of oxalate with a cerium supported palladium oxide: An efficient degradation not relying on hydroxyl radical oxidation

    KAUST Repository

    Zhang, Tao; Li, Weiwei; Croue, Jean-Philippe

    2011-01-01

    The cerium supported palladium oxide (PdO/CeO 2) at a low palladium loading was found very effective in catalytic ozonation of oxalate, a probe compound that is difficult to be efficiently degraded in water with hydroxyl radical oxidation and one of the major byproducts in ozonation of organic matter. The oxalate was degraded into CO 2 during the catalytic ozonation. The molar ratio of oxalate degraded to ozone consumption increased with increasing catalyst dose and decreasing ozone dosage and pH under the conditions of this study. The maximum molar ratio reached around 1, meaning that the catalyst was highly active and selective for oxalate degradation in water. The catalytic ozonation, which showed relatively stable activity, does not promote hydroxyl radical generation from ozone. Analysis with ATR-FTIR and in situ Raman spectroscopy revealed that 1) oxalate was adsorbed on CeO 2 of the catalyst forming surface complexes, and 2) O 3 was adsorbed on PdO of the catalyst and further decomposed to surface atomic oxygen (*O), surface peroxide (*O 2), and O 2 gas in sequence. The results indicate that the high activity of the catalyst is related to the synergetic function of PdO and CeO 2 in that the surface atomic oxygen readily reacts with the surface cerium-oxalate complex. This kind of catalytic ozonation would be potentially effective for the degradation of polar refractory organic pollutants and hydrophilic natural organic matter. © 2011 American Chemical Society.

  2. Relying on Visiting Foreign Doctors for Fistula Repair: The Profile of Women Attending Fistula Repair Surgery in Somalia.

    Science.gov (United States)

    Gele, Abdi A; Salad, Abdulwahab M; Jimale, Liban H; Kour, Prabhjot; Austveg, Berit; Kumar, Bernadette

    2017-01-01

    Obstetric fistula is treatable by surgery, although access is usually limited, particularly in the context of conflict. This study examines the profile of women attending fistula repair surgery in three hospitals in Somalia. A cross-sectional study was conducted in Somalia from August to September 2016. Structured questionnaires were administered to 81 women who registered for fistula repair surgery in the Garowe, Daynile, and Kismayo General Hospitals in Somalia. Findings revealed that 70.4% of the study participants reported obstetric labor as the cause of their fistula, and 29.6% reported iatrogenic causes. Regarding the waiting time for the repair surgery, 45% waited for the surgery for over one year, while the rest received the surgery within a year. The study suggests that training for fistula surgery has to be provided for healthcare professionals in Somalia, fistula centers should be established, and access to these facilities has to be guaranteed for all patients who need these services.

  3. Marquardt's Phi mask: pitfalls of relying on fashion models and the golden ratio to describe a beautiful face.

    Science.gov (United States)

    Holland, E

    2008-03-01

    Stephen Marquardt has derived a mask from the golden ratio that he claims represents the "ideal" facial archetype. Many have found his mask convincing, including cosmetic surgeons. However, Marquardt's mask is associated with numerous problems. The method used to examine goodness of fit with the proportions in the mask is faulty. The mask is ill-suited for non-European populations, especially sub-Saharan Africans and East Asians. The mask also appears to approximate the face shape of masculinized European women. Given that the general public strongly and overwhelmingly prefers above average facial femininity in women, white women seeking aesthetic facial surgery would be ill-advised to aim toward a better fit with Marquardt's mask. This article aims to show the proper way of assessing goodness of fit with Marquardt's mask, to address the shape of the mask as it pertains to masculinity-femininity, and to discuss the broader issue of an objective assessment of facial attractiveness. Generalized Procrustes analysis is used to show how goodness of fit with Marquardt's mask can be assessed. Thin-plate spline analysis is used to illustrate visually how sample faces, including northwestern European averages, differ from Marquardt's mask. Marquardt's mask best describes the facial proportions of masculinized white women as seen in fashion models. Marquardt's mask does not appear to describe "ideal" face shape even for white women because its proportions are inconsistent with the optimal preferences of most people, especially with regard to femininity.

  4. Evaluation Techniques of Creating Coherence in Poems of Kaiser Aminpour Relying on the Theory of Halliday’s Linguistics

    Directory of Open Access Journals (Sweden)

    Reza Sattari

    2016-05-01

    Full Text Available AbstractOne of the linguistics theories that are utilized in present age in the analysis of literary texts is the theory of Halliday’s linguistics which is called theory of systemic - functional linguistics. Halliday’s theory in the second half of the twentieth century, in contrast to the "generative linguistics" approach, which is based on formal language like a mental and individual phenomenon.    Hallidayan called the semantic, literal, syntax and logical relationship of words as coherence of a text and believes that the coherence of the text, includes all the semantic relations by which, every piece of speech or writing can serve as text. Hence, cohesion, referred to relations that relates all elements of a sentence to the elements of other sentences. From Hallidayan's  point of view, elements of coherence of a text are divided into two parts: grammatical and lexical. Grammatical cohesion includes factors such as referrals, replacements, removals and relevancy, and lexical coherence includes repetition and collocation in literary language.   Kaiser is one of the contemporary famous poets that have composed many poets in different molds of poetry. Kaiser Manipur's poems benefit the integration due to the poet's fluency in Persian and his familiarity with the vocabulary and grammatical and lexical capacities of Persian literature. In this research, we have studied the cohesion in Kaiser Manipur's poems from two views of lexical and grammatical by using Holidaying theory of coherence as well as the techniques that the poet has applied to reach the cohesion in his poems.    The method of research in the present paper is descriptive-analytical and all the information and data has been collected from the sources of library and electronic. In this paper, we first briefly discussed the Holidaying coherence theory, and then, with a special approach to this theory, the most important techniques that Kaiser Manipur has benefited to create the coherence in his poems and poetry, analyzed and investigated.   The Research results indicate that the poems of Kaiser Manipur have a specific integration due to the poet's fluency in Persian and his familiarity with the vocabulary and grammatical and lexical capacities of Persian literature. Hence, techniques of creating coherence in two aspects of grammatical cohesion and lexical cohesion in Kaiser Manipur's poetry are considerable. Grammatical coherence in his poems is achieved through techniques such as references, omission, and relevance. And the techniques of lexica coherence in his poems are: using phonemes, repeating the words, pun, repeated sentence, the balance, the heart of the matter, proportion, contrast, sequence and so on.    Kaiser Aminpour has widely used the techniques of lexical and grammatical coherence in his poems, so that in most of his poems we can see several techniques used together in a way to reach the mentioned coherence. Hence, we can say he is a poet who knows his language as well as words and has the complete power of selection and combination of words and sentences. And his poems are very coherent and the sentences and phrases are intertwined and related to each other in his poetry.Keywords: Kaiser Aminpour, Hallidayan, functional linguistics, grammatical cohesion, lexical cohesion.References 1.      Abdollahi, Manije (2005. Vertical link and semantic cohesion in the ghazals of Hafez. Journal of Humanities and Social Sciences, University of Shiraz, (Vol. 22. No 3(44. P.p: 124- 134. [In Persian].2.      Afrashi, Azita (1999. A look to the issue of collocation of words. Language and Literature, No 7 & 8. p.p: 73- 83. [In Persian].3.      Aghahosseini, H. & Gholami, Mojahed. (2010. Indian poetry style aesthetic effects on the resistance poetry of Kaiser Aminpour's poetry. Journal of resistance literature at Kerman Shahid Bahonar University. Year, 1. No, 2. P.p: 1- 29. [In Persian]. 4.      Ahmadzadeh, Mostafa. (2008. Linguistic interpretation of Surah Al-Asr. Islamic Studies: Quran and Hadith Sciences. Year 40. No, 3/18. P.p: 11-35. [In Persian].5.       Alavi-moghaddam, M. (1998. Contemporary literary criticism theories (formalism and structuralism. Tehran: Samt. [In Persian].6.      Aminpour, Kaisar (2011. Complete collection of kaisar Aminpour's poems. 8th ed., Tehran: Morvarid. [In Persian].Abdollahi, M. (2005.  7.      Behjo, Zohre (1998. Encoding scheme of methods of coherence in Persian language. Farhang, No 25 & 26. P.p: 189- 212. [In Persian].8.      Fotohi, M. (2008. Three voices, three colors, three styles of Aminpour’s poem. Literature Studies, University of Guilan. No 5. P.p: 9-30. [In Persian].9.      Ghobadi, H. & Rezaei-Jamkarani, A. (2011. Review, analysis and criticism of four Persian odes based on the teachings of systemic-functional linguistics. Journal of Persian Language and Literature. No 20. P.p: 69- 93. [In Persian].10.  Gholamhosseinzade, GH. & Norouzi, H. (2010.  Role of Phonetic repeating in lexical Cohesion in prosodic Persian poetry. Journal of Literature and Language University of Kerman. No, 27. P.p: 251- 281. [In Persian].11.  Halliday, M. A. K & Hasan, R. (1976 Cohesion in English. London: Longman, [In English].12.  Halliday, M. A. K. (1985. An Introduction to Functional Grammar. London: Edward Arnold. [In English].13.  Jahangiri, N. & Zakipour, Sh. (2005. Lexical cohesion in Persian short stories for children. Literary Notes (Journal of Ferdowsi University of Mashhad. No 151. P.p: 1-20. [In Persian].14.  Khanjan, A. & Mirza, Z. (2006. Introduction to the functional poetry (linguistic approaches. Journal of Persian Language and Literature. No 7. P.p: 83- 101. [In Persian].15.  Lotfipour-saedi, K. (1992. An introduction to the principles and methods of translation. Tehran: Academic publishing. [In Persian].16.  Martine, A. (2001. Phonetic transformation balance. (H. Milanian Trans. Terhan: Hermes. [In Persian].17.  Moein od-Dini, F. (2003.  Techniques to create coherence in kalila and demna. Farhang, No 47 & 47. P.p: 303- 326. [In Persian].18.  Mohajer, M. & Nabavi, M. (1997. Towards the linguistic poetry: the functional approach. Tehran: Markaz. [In Persian].19.  Natel Khanlari, P. (2007. Persian poetry weight. 7th ed., Tehran: toos. [In Persian].20.  Panahi, S. (2002. The process of collocation and collocation compounds in Persian language. Journal of Academy. No19. P.p: 199- 211. [In Persian].21.  Rastgoo, M. (2004. Speak art layout (art of badie. Tehran: Samt. [In Persian].22.  Rouhani, M. (2011.  Study of Repeats' Functions in Contemporary Poetry (based on poetry of Sepehri, Shamloo and Forough. Journal of Boostan Adab (university of Shiraz. Year 3. No 2/8. P.p: 145- 168. [In Persian].23.  Safavi, K. (2008. Introduction to Semantics. 3rd ed., Tehran: Sore-ye Mehr. [In Persian]. 24.  Safavi, K. (1994. From linguistics to literature. (Vol: 1. Tehran: Cheshme. [In Persian].25.  Salehi, F. (2007.  Semantics and functional grammar of Halliday. Literature Book of the Month. No 8. P.p: 32-41. [In Persian].26.  Sarli, N. & Ishani, T. (2011.  Coherence and Coordination of cohesion Theory and its Application in a Minimal Story Persian (The Story of the Ladder. Journal of Language Scholarships (university of az-Zahra. Year 2. No 4. P.p: 51- 77. [In Persian].27.  Shabanloo, A. & Maleksabet, M. & Jalali, Y. (2008.  Grammatical cohesion process in the long poem of am'aq Bukhari. Journal of Gawhar-i Guya. No 5. P.p: 165- 188. [In Persian].28.  Shafi’ee kadkani, M. (2005. Music of Lyrics. (8th ed., Tehran: Agah. [In Persian].29.  Shamisa, S. (2007. Figures of speech: a new look to Ba'die. 2nd ed., Tehran: Mitra. [In Persian].30.  Vafaei, A. & Alinoori, Z. (2010. Artistic symmetry in two axes of succession and Companion in poems of Kaiser Aminpour. Journal of Persian Language and Literature. Year 2. No 6. P: 99- 118. [In Persian].31.  Velek, R. & Varen, A. (2003. Theory of Literatur. (Z. Movahhed & P. Mohajer Trans. Tehran: Elmi- Farhangi. [In Persian].Yahaghi, M. & Fallahi, M. (2010.  Saadi's and Bidel Dehlavi's sonnets text cohesion, evaluation and comparison of ten sonnets of Sa'di, and ten sonnets of Bidel. Journal of Literature and Language University of Kerman. No 27. P: 327- 346. [In Persian].

  5. Organizational Strategic Planning and Execution: Should Governmental Organizations Rely on Strategic Planning for the Success of the Organization?

    National Research Council Canada - National Science Library

    Young, Lester; Reynolds, Thomas E; Harris, II, Thomas L

    2007-01-01

    .... The utilization of this tool can yield positive results for many companies and organizations. On the other hand, if the strategic plan is not utilized, it becomes a costly paperweight on a table in the executive suite...

  6. Do countries rely on the World Health Organization for translating research findings into clinical guidelines? A case study.

    Science.gov (United States)

    Noor, Ramadhani A; Geldsetzer, Pascal; Bärnighausen, Till; Fawzi, Wafaie

    2016-10-06

    The World Health Organization's (WHO) antiretroviral therapy (ART) guidelines have generally been adopted rapidly and with high fidelity by countries in sub-Saharan Africa. Thus far, however, WHO has not published specific guidance on nutritional care and support for (non-pregnant) adults living with HIV despite a solid evidence base for some interventions. This offers an opportunity for a case study on whether national clinical guidelines in sub-Saharan Africa provide concrete recommendations in the face of limited guidance by WHO. This study, therefore, aims to determine if national HIV treatment guidelines in sub-Saharan Africa contain specific guidance on nutritional care and support for non-pregnant adults living with HIV. We identified the most recent national HIV treatment guidelines in sub-Saharan African countries with English as an official language. Using pre-specified criteria, we determined for each guideline whether it provides guidance to clinicians on each of five components of nutritional care and support for adults living with HIV: assessment of nutritional status, dietary counseling, micronutrient supplementation, ready-to-use therapeutic or supplementary foods, and food subsidies. We found that national HIV treatment guidelines in sub-Saharan Africa generally do not contain concrete recommendations on nutritional care and support for non-pregnant adults living with HIV. Given that decisions on nutritional care and support are inevitably being made at the clinician-patient level, and that clinicians have a relative disadvantage in systematically identifying, summarizing, and weighing up research evidence compared to WHO and national governments, there is a need for more specific clinical guidance. In our view, such guidance should at a minimum recommend daily micronutrient supplements for adults living with HIV who are in pre-ART stages, regular dietary counseling, periodic assessment of anthropometric status, and additional nutritional management of undernourished patients. More broadly, our findings suggest that countries in sub-Saharan Africa look to WHO for guidance in translating evidence into clinical guidelines. It is, thus, likely that the development of concrete recommendations by WHO on nutritional interventions for people living with HIV would lead to more specific guidelines at the country-level and, ultimately, better clinical decisions and treatment outcomes.

  7. Can we rely on Swedish granites and gneisses as sage host rock for hazardous waste disposal during future geological periods?

    International Nuclear Information System (INIS)

    Morfeldt, C.O.; Morfeldt, D.

    1991-01-01

    The rapid growth of our industrial societies, together with an increased awareness and sense of responsibility towards the environment in most countries, has made us being to understand the urgency of halting and preventing further pollution and destruction of irreparable environments. The main issue sat present focus on neutralizing the harmful effects of toxic waste by isolating it from the biosphere for long periods of time, perhaps for many hundreds of thousands of years. These issues no longer focus on radioactive substances and their harmful ionizing radiation effects but also on heavy alloys and chemical pollutants generated during transformation processes of different types of waste, or through incineration of waste. Ash and sedimentary deposits from sewage plants for example, also contain heavy alloys. (au)

  8. Do we really rely on fast for decision-making in the management of blunt abdominal trauma?

    Science.gov (United States)

    Carter, Jeffrey W; Falco, Mark H; Chopko, Michael S; Flynn, William J; Wiles Iii, Charles E; Guo, Weidun Alan

    2015-05-01

    The Focused Assessment with Sonography in Trauma examination (FAST) is currently taught and recommended in the ATLS(®), often as an addendum to the primary survey for patients with blunt abdominal trauma. Although it is non-invasive and rapidly performed at bedside, the utility of FAST in blunt abdominal trauma has been questioned. We designed this study to examine our hypothesis that FAST is not an efficacious screening tool for identifying intra-abdominal injuries. We performed a retrospective chart review of all patients with confirmatory diagnosis of blunt abdominal injuries with CT and/or laparotomy for a period of 1.5 years (from 7/2009 to 11/2010). FAST was performed by ED residents and considered positive when free intra-abdominal fluid was visualized. Abdominal CT, or exploratory laparotomy findings were used as confirmation of intra-abdominal injury. A total of 1671 blunt trauma patients were admitted to and evaluated in the Emergency Department during a 1½ year period and 146 patients were confirmed intra-abdominal injuries by CT and/or laparotomy. Intraoperative findings include injuries to the liver, spleen, kidneys, and bowels. In 114 hemodynamically stable patients, FAST was positive in 25 patients, with a sensitivity of 22%. In 32 hemodynamically unstable patients, FAST was positive in 9 patients, with a sensitivity of 28%. A free peritoneal fluid and splenic injury are associated with a positive FAST on univariate analysis, and are the independent predictors for a positive FAST on multiple logistic regression. FAST has a very low sensitivity in detecting blunt intraabdominal injury. In hemodynamically stable patients, a negative FAST without a CT may result in missed intra-abdominal injuries. In hemodynamically unstable blunt trauma patients, with clear physical findings on examination, the decision for exploratory laparotomy should not be distracted by a negative FAST. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. The Importance of Relying on the Manual: Scoring Error Variance in the WISC-IV Vocabulary Subtest

    Science.gov (United States)

    Erdodi, Laszlo A.; Richard, David C. S.; Hopwood, Christopher

    2009-01-01

    Classical test theory assumes that ability level has no effect on measurement error. Newer test theories, however, argue that the precision of a measurement instrument changes as a function of the examinee's true score. Research has shown that administration errors are common in the Wechsler scales and that subtests requiring subjective scoring…

  10. How much will BC rely on incoming LNG and locally produced natural gas to fuel future generation capacity

    International Nuclear Information System (INIS)

    Boychuk, L.A.

    2005-01-01

    The British Columbia Utilities Commission (BCUC) works with public utilities to determine where resource additions are needed in order to ensure safe, reliable and convenient service to utility customers. All public utilities in the province are required to file resource plans in order to enhance the effectiveness of the BCUC and to protect ratepayers from poor utility expenditure decisions. The BCUC also ensures that utilities have adequate supply to meet demand. This paper outlined energy policy actions plans for the province of British Columbia. The BCUC will regulate BC hydro rates and will review the Vancouver Island Generation Project (VIGP) to determine if it is the most cost-effective means to reliably meet power needs on the island. Electricity distributors will acquire new supply on a least-cost basis, with regulatory oversight by BCUC. The role of the private sector in developing new electricity generation was also discussed, along with alternative energy development opportunities, such as the potential liquefied natural gas (LNG) import project by Galveston at Kitimat and WestPac Terminals' project at Prince Rupert

  11. Do Adults with Cochlear Implants Rely on Different Acoustic Cues for Phoneme Perception than Adults with Normal Hearing?

    Science.gov (United States)

    Moberly, Aaron C.; Lowenstein, Joanna H.; Tarr, Eric; Caldwell-Tarr, Amanda; Welling, D. Bradley; Shahin, Antoine J.; Nittrouer, Susan

    2014-01-01

    Purpose: Several acoustic cues specify any single phonemic contrast. Nonetheless, adult, native speakers of a language share weighting strategies, showing preferential attention to some properties over others. Cochlear implant (CI) signal processing disrupts the salience of some cues: In general, amplitude structure remains readily available, but…

  12. Individuals with high obsessive-compulsive tendencies or undermined confidence rely more on external proxies to access their internal states.

    Science.gov (United States)

    Zhang, Zhongming; Wang, Mengyun; Miao, Xiaocui; Li, Yijuan; Hitchman, Glenn; Yuan, Zhen

    2017-03-01

    The Seeking Proxies for Internal States (SPIS) hypothesis predicts that obsessive-compulsive disorder (OCD) is associated with a deficit in subjective convictions, which may lead to a reliance on external substitutes for the perceptions of an individual's internal states. Two well-designed studies were performed for the present work that adopted a false bio-feedback procedure in a muscle tension task to examine the SPIS hypothesis. The false bio-feedback paradigm was used to investigate our hypothesis. NeXus-10 Mark II hardware and V2011 BioTrace + software (Mind Media B.V., Herten, Netherlands) were utilized to measure the muscle tension of the flexor carpiulnaris muscle, which characterized the target's internal state. In addition, false EMG changes were recorded and displayed on a computer monitor and were considered external proxies. Study 1 demonstrated that the participants with high obsessive-compulsive (OC) tendencies were more affected by the false bio-feedback and exhibited lower confidence in their judgments regarding their muscle tension compared with the participants with low OC tendencies. These findings indicate that subjects with high OC tendencies were more influenced by self-perception effects. In contrast, the subjects in the undermined confidence group in Study 2 were more easily influenced by the false bio-feedback compared with the control group, which suggests that the subjects in the undermined confidence group were more affected by self-perception effects. We did not combine the undermined confidence with OC tendencies or OCD symptoms in our paradigm to investigate their joint effects on self-perception. Our findings provide further evidence that supports the SPIS hypothesis, which indicates that OC tendencies and the confidence in an individual's recognition of internal states appear to have similar effects on the assessment of internal states and reliance on proxies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Marketing communications in industrial B2b markets enhancing the value of the corporate brand relying on common added values

    Directory of Open Access Journals (Sweden)

    Jose Ignacio Monrabal

    2013-09-01

    Full Text Available Today, industrial Business-to-Business (B2B markets are mainly characterized by a highly trained customer for making rational decisions in a highly competitive and global market, requiring more than ever organizations to approach their markets with a single and consistent message. Such demanding scenario requires to define a corporate brand transmitting in one message all the advantages that a Customer may appreciate in the long-term, based not only on what the company stands for in the market, but also the benefits of all its products throughout its portfolio. Such elements are referred as Common Added Values (CAVs, being some general examples the technology, quality, innovation and reliability; the capacity, infrastructure and distribution network; after-sales service policies, support and training; or the price and financial policies. This paper tries to explain the source of this need, describing the main differences between a brand communications model focused on the product or including the main B2B corporate values; and highlighting the main CAVs, to get an industry player either small or large, can succeed in generating brand equity through an integrated marketing communications strategy.

  14. Organizational Strategic Planning and Execution: Should Governmental Organizations Rely on Strategic Planning for the Success of the Organization?

    Science.gov (United States)

    2007-06-01

    Competition that it faces. 16 The analysis of internal factors will include (IV) the company’s marketing mix ; (V) the internal resources; and (VI) a variety...Government; Economy; Socio-Demography; Technology) III Industry & Competition IV Marketing Mix (Outputs) A B C V Internal Resource

  15. Can We Rely on Predicted Basal Metabolic Rate in Patients With Intestinal Failure on Home Parenteral Nutrition?

    Science.gov (United States)

    Skallerup, Anders; Nygaard, Louis; Olesen, Søren Schou; Vinter-Jensen, Lars; Køhler, Marianne; Rasmussen, Henrik Højgaard

    2017-09-01

    Intestinal failure (IF) is a serious and common complication of short bowel syndrome with patients depending on parenteral nutrition (PN) support. Effective nutrition management requires an accurate estimation of the patient's basal metabolic rate (BMR) to avoid underfeeding or overfeeding. However, indirect calorimetry, considered the gold standard for BMR assessment, is a time- and resource-consuming procedure. Consequently, several equations for prediction of BMR have been developed in different settings, but their accuracy in patients with IF are yet to be investigated. We evaluated the accuracy of predicted BMR in clinically stable patients with IF dependent on home parenteral nutrition (HPN). In total, 103 patients with IF were included. We used indirect calorimetry for assessment of BMR and calculated predicted BMR using different equations based on anthropometric and/or bioelectrical impedance parameters. The accuracy of predicted BMR was evaluated using Bland-Altman analysis with measured BMR as the gold standard. The average measured BMR was 1272 ± 245 kcal/d. The most accurate estimations of BMR were obtained using the Harris-Benedict equation (mean bias, 14 kcal/d [ P = .28]; limits of agreement [LoA], -238 to 266 kcal/d) and the Johnstone equation (mean bias, -16 kcal/d [ P = .24]; LoA, -285 to 253 kcal/d). For both equations, 67% of patients had a predicted BMR from 90%-110% All other equations demonstrated a statistically and clinically significant difference between measured and predicted BMR. The Harris-Benedict and Johnstone equations reliably predict BMR in two-thirds of clinically stable patients with IF on HPN.

  16. Diagnosis of sclerosing hemangioma of lung: Don′t rely on fine-needle aspiration cytology diagnosis alone

    Directory of Open Access Journals (Sweden)

    Kaushik Saha

    2013-01-01

    Full Text Available Sclerosing hemangioma is a rare variety of benign pulmonary neoplasm. It usually presents as asymptomatic, solitary, peripheral, circumscribed lesions in middle-aged women. Here, we describe a 46-year-old woman presenting to us for evaluation of right parahilar lung mass. Previous chest radiography done 10 years back showed a lung mass of almost similar size. Computed Tomography (CT-guided fine-needle aspiration cytology (FNAC was suggestive of adenocarcinoma of lung. A well-circumscribed, capsulated, ovoid mass measuring 5.6 cm × 4 cm × 3 cm, adjacent to the transverse fissure of the right lung was excised by lateral thoracotomy. Histopathological examination along with immunohistochemistry was suggestive of sclerosing hemangioma of lung. A pathologist must consider the clinicoradiological features before coming to a final diagnosis of lung malignancy from FNAC. Whenever there is any confusion regarding lung mass, thoracotomy must be done for arriving at an exact diagnosis from histopathology.

  17. Multiple source genes of HAmo SINE actively expanded and ongoing retroposition in cyprinid genomes relying on its partner LINE

    Directory of Open Access Journals (Sweden)

    Gan Xiaoni

    2010-04-01

    Full Text Available Abstract Background We recently characterized HAmo SINE and its partner LINE in silver carp and bighead carp based on hybridization capture of repetitive elements from digested genomic DNA in solution using a bead-probe 1. To reveal the distribution and evolutionary history of SINEs and LINEs in cyprinid genomes, we performed a multi-species search for HAmo SINE and its partner LINE using the bead-probe capture and internal-primer-SINE polymerase chain reaction (PCR techniques. Results Sixty-seven full-size and 125 internal-SINE sequences (as well as 34 full-size and 9 internal sequences previously reported in bighead carp and silver carp from 17 species of the family Cyprinidae were aligned as well as 14 new isolated HAmoL2 sequences. Four subfamilies (type I, II, III and IV, which were divided based on diagnostic nucleotides in the tRNA-unrelated region, expanded preferentially within a certain lineage or within the whole family of Cyprinidae as multiple active source genes. The copy numbers of HAmo SINEs were estimated to vary from 104 to 106 in cyprinid genomes by quantitative RT-PCR. Over one hundred type IV members were identified and characterized in the primitive cyprinid Danio rerio genome but only tens of sequences were found to be similar with type I, II and III since the type IV was the oldest subfamily and its members dispersed in almost all investigated cyprinid fishes. For determining the taxonomic distribution of HAmo SINE, inter-primer SINE PCR was conducted in other non-cyprinid fishes, the results shows that HAmo SINE- related sequences may disperse in other families of order Cypriniforms but absent in other orders of bony fishes: Siluriformes, Polypteriformes, Lepidosteiformes, Acipenseriformes and Osteoglossiforms. Conclusions Depending on HAmo LINE2, multiple source genes (subfamilies of HAmo SINE actively expanded and underwent retroposition in a certain lineage or within the whole family of Cyprinidae. From this perspective, HAmo SINE should provide useful phylogenetic makers for future analyses of the evolutionary relationships among species in the family Cyprinidae.

  18. Nocturnal Foraging by Red-Legged Kittiwakes, a Surface Feeding Seabird That Relies on Deep Water Prey During Reproduction.

    Science.gov (United States)

    Kokubun, Nobuo; Yamamoto, Takashi; Kikuchi, Dale M; Kitaysky, Alexander; Takahashi, Akinori

    2015-01-01

    Narrow foraging specialization may increase the vulnerability of marine predators to climate change. The red-legged kittiwake (Rissa brevirostris) is endemic to the Bering Sea and has experienced drastic population fluctuations in recent decades, presumably due to climate-driven changes in food resources. Red-legged kittiwakes are presumed to be a nocturnal surface-foraging seabird that feed almost entirely on deep water Myctophidae fishes. However, there is little empirical evidence confirming their nocturnal foraging activity during the breeding season. This study investigated the foraging behavior of red-legged kittiwakes by combining GPS tracking, accelerometry, and dietary analyses at the world's largest breeding colony of red-legged kittiwakes on St. George I. GPS tracking of 5 individuals revealed that 82.5% of non-flight behavior (including foraging and resting) occurred over the ocean basin (bottom depth >1,000 m). Acceleration data from 4 birds showed three types of behaviors during foraging trips: (1) flight, characterized by regular wing flapping, (2) resting on water, characterized by non-active behavior, and (3) foraging, when wing flapping was irregular. The proportions of both foraging and resting behaviors were higher at night (14.1 ± 7.1% and 20.8 ± 14.3%) compared to those during the day (6.5 ± 3.0% and 1.7 ± 2.7%). The mean duration of foraging (2.4 ± 2.9 min) was shorter than that of flight between prey patches (24.2 ± 53.1 min). Dietary analyses confirmed myctophids as the dominant prey (100% by occurrence and 98.4 ± 2.4% by wet-weight). Although the sample size was limited, these results suggest that breeding red-legged kittiwakes concentrated their foraging on myctophids available at the surface during nighttime in deep water regions. We propose that the diel patterns and ephemeral nature of their foraging activity reflected the availability of myctophids. Such foraging specialization may exacerbate the vulnerability of red-legged kittiwakes to climate change in the Bering Sea.

  19. Nocturnal Foraging by Red-Legged Kittiwakes, a Surface Feeding Seabird That Relies on Deep Water Prey During Reproduction.

    Directory of Open Access Journals (Sweden)

    Nobuo Kokubun

    Full Text Available Narrow foraging specialization may increase the vulnerability of marine predators to climate change. The red-legged kittiwake (Rissa brevirostris is endemic to the Bering Sea and has experienced drastic population fluctuations in recent decades, presumably due to climate-driven changes in food resources. Red-legged kittiwakes are presumed to be a nocturnal surface-foraging seabird that feed almost entirely on deep water Myctophidae fishes. However, there is little empirical evidence confirming their nocturnal foraging activity during the breeding season. This study investigated the foraging behavior of red-legged kittiwakes by combining GPS tracking, accelerometry, and dietary analyses at the world's largest breeding colony of red-legged kittiwakes on St. George I. GPS tracking of 5 individuals revealed that 82.5% of non-flight behavior (including foraging and resting occurred over the ocean basin (bottom depth >1,000 m. Acceleration data from 4 birds showed three types of behaviors during foraging trips: (1 flight, characterized by regular wing flapping, (2 resting on water, characterized by non-active behavior, and (3 foraging, when wing flapping was irregular. The proportions of both foraging and resting behaviors were higher at night (14.1 ± 7.1% and 20.8 ± 14.3% compared to those during the day (6.5 ± 3.0% and 1.7 ± 2.7%. The mean duration of foraging (2.4 ± 2.9 min was shorter than that of flight between prey patches (24.2 ± 53.1 min. Dietary analyses confirmed myctophids as the dominant prey (100% by occurrence and 98.4 ± 2.4% by wet-weight. Although the sample size was limited, these results suggest that breeding red-legged kittiwakes concentrated their foraging on myctophids available at the surface during nighttime in deep water regions. We propose that the diel patterns and ephemeral nature of their foraging activity reflected the availability of myctophids. Such foraging specialization may exacerbate the vulnerability of red-legged kittiwakes to climate change in the Bering Sea.

  20. Adaptation of the symbiotic Mesorhizobium-chickpea relationship to phosphate deficiency relies on reprogramming of whole-plant metabolism.

    Science.gov (United States)

    Nasr Esfahani, Maryam; Kusano, Miyako; Nguyen, Kien Huu; Watanabe, Yasuko; Ha, Chien Van; Saito, Kazuki; Sulieman, Saad; Herrera-Estrella, Luis; Tran, L S

    2016-08-09

    Low inorganic phosphate (Pi) availability is a major constraint for efficient nitrogen fixation in legumes, including chickpea. To elucidate the mechanisms involved in nodule acclimation to low Pi availability, two Mesorhizobium-chickpea associations exhibiting differential symbiotic performances, Mesorhizobium ciceri CP-31 (McCP-31)-chickpea and Mesorhizobium mediterranum SWRI9 (MmSWRI9)-chickpea, were comprehensively studied under both control and low Pi conditions. MmSWRI9-chickpea showed a lower symbiotic efficiency under low Pi availability than McCP-31-chickpea as evidenced by reduced growth parameters and down-regulation of nifD and nifK These differences can be attributed to decline in Pi level in MmSWRI9-induced nodules under low Pi stress, which coincided with up-regulation of several key Pi starvation-responsive genes, and accumulation of asparagine in nodules and the levels of identified amino acids in Pi-deficient leaves of MmSWRI9-inoculated plants exceeding the shoot nitrogen requirement during Pi starvation, indicative of nitrogen feedback inhibition. Conversely, Pi levels increased in nodules of Pi-stressed McCP-31-inoculated plants, because these plants evolved various metabolic and biochemical strategies to maintain nodular Pi homeostasis under Pi deficiency. These adaptations involve the activation of alternative pathways of carbon metabolism, enhanced production and exudation of organic acids from roots into the rhizosphere, and the ability to protect nodule metabolism against Pi deficiency-induced oxidative stress. Collectively, the adaptation of symbiotic efficiency under Pi deficiency resulted from highly coordinated processes with an extensive reprogramming of whole-plant metabolism. The findings of this study will enable us to design effective breeding and genetic engineering strategies to enhance symbiotic efficiency in legume crops.

  1. Design basis knowledge management for the newcomer countries. Relying on the owner/operator as a knowledgeable customer

    International Nuclear Information System (INIS)

    Lepouze, Benoît

    2013-01-01

    Becoming a knowledgeable customer is the first step to manage knowledge: • Vendors, consulting firms, TSOs can assist the future operator but it will remain the sole owner of the decisions; • Future owner operator has to become a knowledgeable customer: • Know what to ask for, • Know how to ask for it, • Know how to check if it got what it asked. • Where should knowledge management belong (management?, HRD?, procurement?) and is it important? What it means for DBKM ? (example): • The owner/operator (the licensee) is responsible in front of the safety agency: it should answer its questions at every stage of the program; • It will often turn back to its vendor/suppliers especially for detailed design questions; • But that means it has to know what to ask for and to check the result before talking to the regulator; • That also means it has to make sure knowledge is managed throughout the life of the program

  2. Self-control depletion in tufted capuchin monkeys (Sapajus spp.): does delay of gratification rely on a limited resource?

    Science.gov (United States)

    Petrillo, Francesca De; Gori, Emanuele; Truppa, Valentina; Ariely, Dan; Addessi, Elsa

    2015-01-01

    Self-control failure has enormous personal and societal consequences. One of the most debated models explaining why self-control breaks down is the Strength Model, according to which self-control depends on a limited resource. Either previous acts of self-control or taking part in highly demanding cognitive tasks have been shown to reduce self-control, possibly due to a reduction in blood glucose levels. However, several studies yielded negative findings, and recent meta-analyses questioned the robustness of the depletion effect in humans. We investigated, for the first time, whether the Strength Model applies to a non-human primate species, the tufted capuchin monkey. We tested five capuchins in a self-control task (the Accumulation task) in which food items were accumulated within individual’s reach for as long as the subject refrained from taking them. We evaluated whether capuchins’ performance decreases: (i) when tested before receiving their daily meal rather than after consuming it (Energy Depletion Experiment), and (ii) after being tested in two tasks with different levels of cognitive complexity (Cognitive Depletion Experiment). We also tested, in both experiments, how implementing self-control in each trial of the Accumulation task affected this capacity within each session and/or across consecutive sessions. Repeated acts of self-control in each trial of the Accumulation task progressively reduced this capacity within each session, as predicted by the Strength Model. However, neither experiencing a reduction in energy level nor taking part in a highly demanding cognitive task decreased performance in the subsequent Accumulation task. Thus, whereas capuchins seem to be vulnerable to within-session depletion effects, to other extents our findings are in line with the growing body of studies that failed to find a depletion effect in humans. Methodological issues potentially affecting the lack of depletion effects in capuchins are discussed. PMID:26322001

  3. Can we rely on cancer mortality data? Checking the validity of cervical cancer mortality data for Slovenia

    International Nuclear Information System (INIS)

    Primic Zakelj, M.; Pompe Kirn, V.; Skrlec, F.; Selb, J.

    2001-01-01

    Background. Valid inference on cervical cancer mortality is very difficult since - on the basis of death certificates - it is not always possible to distinguish between cervix, corpus and unspecified uterine cancer deaths. Our aim was to estimate the extent to which cervical cancer as the official cause of death reflects the true mortality from cervical cancer in Slovenia. Material and methods. The data on 2245 deaths from cervix, corpus uteri, and uterus-unspecified cancers for the period 1985-1999 were linked to the Cancer Registry of Slovenia database from the mortality database of Slovenia. Results. Officially, in the period 1985-1999, there were 878 cervical cancer deaths. The comparison of these causes of death with the cancer sites registered in the Cancer Registry revealed that they include only 87.7% patients with a previous diagnosis of cervical cancer. Of 650 corpus uteri cancer deaths, 17. 1 % of patients were registered to have cervical cancer, and of 717 unspecified uterine cancer deaths, 31.4% were registered. Taking into account the correctly identified cervical cancer cases among cervical cancer deaths and misclassified cervical cancer deaths as corpus uteri and unspecified uterine, the corrected number of deaths would be 1106. Conclusions. When evaluating the impact of cervical cancer mortality from national mortality rates, the stated underestimation should be taken into account. However, this does not hold for some other cancers. (author)

  4. Design of a Simple and Modular 2-DOF Ankle Physiotherapy Device Relying on a Hybrid Serial-Parallel Robotic Architecture

    Directory of Open Access Journals (Sweden)

    Christos E. Syrseloudis

    2011-01-01

    Full Text Available The aim of this work is to propose a new 2-DOF robotic platform with hybrid parallel-serial structure and to undertake its parametric design so that it can follow the whole range of ankle related foot movements. This robot can serve as a human ankle rehabilitation device. The existing ankle rehabilitation devices present typically one or more of the following shortcomings: redundancy, large size, or high cost, hence the need for a device that could offer simplicity, modularity, and low cost of construction and maintenance. In addition, our targeted device must be safe during operation, disallow undesirable movements of the foot, while adaptable to any human foot. Our detailed study of foot kinematics has led us to a new hybrid architecture, which strikes a balance among all aforementioned goals. It consists of a passive serial kinematics chain with two adjustable screws so that the axes of the chain match the two main ankle-axes of typical feet. An active parallel chain, which consists of two prismatic actuators, provides the movement of the platform. Thus, the platform can follow the foot movements, thanks to the passive chain, and also possesses the advantages of parallel robots, including rigidity, high stiffness and force capabilities. The lack of redundancy yields a simpler device with lower size and cost. The paper describes the kinematics modelling of the platform and analyses the force and velocity transmission. The parametric design of the platform is carried out; our simulations confirm the platform's suitability for ankle rehabilitation.

  5. Joint ownership of spouses and good faith acquisition of immovables by relying in the real estate cadastre

    Directory of Open Access Journals (Sweden)

    Cvetić Radenka M.

    2016-01-01

    Full Text Available The paper examines the rules on transferring of immovables in the matrimonial ownership regime against the backdrop of general notion of joint ownership and joint ownership (property of spouses. It explores whether the party who invokes the principle of reliance in the real estate cadastre shall be protected in the absence of an explicit rule guaranteeing the protection of a good faith acquirer in case of an unauthoriesd transfer done by one of the spouses. In other words, should for the sake of protection of confidence in legal transactions, acquisition of ownership and other rights in rem exceptionally be allowed by the good faith acquirer, provided that general presumptions under which confidence in accuracy and completeness of public registry of rights on immovables are fulfilled, in case where ownership was not inscribed as a joint ownership. The answer has been given in the absence of general rules on joint ownership, taking into account existing rules in the neighbouring countries, principle of reliance in the real estate cadastre and with due regard to the stance taken by the highest judicial body in the Republic of Serbia. The conclusion is that a spouse who is not inscribed in the public registry should not benefit from the protection against the good faith acquirer.

  6. Effect of arbuscular mycorrhizal and bacterial inocula on nitrate concentration in mesocosms simulating a wastewater treatment system relying on phytodepuration.

    Science.gov (United States)

    Lingua, Guido; Copetta, Andrea; Musso, Davide; Aimo, Stefania; Ranzenigo, Angelo; Buico, Alessandra; Gianotti, Valentina; Osella, Domenico; Berta, Graziella

    2015-12-01

    High nitrogen concentration in wastewaters requires treatments to prevent the risks of eutrophication in rivers, lakes and coastal waters. The use of constructed wetlands is one of the possible approaches to lower nitrate concentration in wastewaters. Beyond supporting the growth of the bacteria operating denitrification, plants can directly take up nitrogen. Since plant roots interact with a number of soil microorganisms, in the present work we report the monitoring of nitrate concentration in macrocosms with four different levels of added nitrate (0, 30, 60 and 90 mg l(-1)), using Phragmites australis, inoculated with bacteria or arbuscular mycorrhizal fungi, to assess whether the use of such inocula could improve wastewater denitrification. Higher potassium nitrate concentration increased plant growth and inoculation with arbuscular mycorrhizal fungi or bacteria resulted in larger plants with more developed root systems. In the case of plants inoculated with arbuscular mycorrhizal fungi, a faster decrease of nitrate concentration was observed, while the N%/C% ratio of the plants of the different treatments remained similar. At 90 mg l(-1) of added nitrate, only mycorrhizal plants were able to decrease nitrate concentration to the limits prescribed by the Italian law. These data suggest that mycorrhizal and microbial inoculation can be an additional tool to improve the efficiency of denitrification in the treatment of wastewaters via constructed wetlands.

  7. Method to mosaic gratings that relies on analysis of far-field intensity patterns in two wavelengths

    Science.gov (United States)

    Hu, Yao; Zeng, Lijiang; Li, Lifeng

    2007-01-01

    We propose an experimental method to coherently mosaic two planar diffraction gratings. The method uses a Twyman-Green interferometer to guarantee the planar parallelism of the two sub-aperture gratings, and obtains the in-plane rotational error and the two translational errors from analysis of the far-field diffraction intensity patterns in two alignment wavelengths. We adjust the relative attitude and position of the two sub-aperture gratings to produce Airy disk diffraction patterns in both wavelengths. In our experiment, the repeatability of in-plane rotation adjustment was 2.35 μrad and that of longitudinal adjustment was 0.11 μm. The accuracy of lateral adjustment was about 2.9% of the grating period.

  8. Argot2: a large scale function prediction tool relying on semantic similarity of weighted Gene Ontology terms.

    Science.gov (United States)

    Falda, Marco; Toppo, Stefano; Pescarolo, Alessandro; Lavezzo, Enrico; Di Camillo, Barbara; Facchinetti, Andrea; Cilia, Elisa; Velasco, Riccardo; Fontana, Paolo

    2012-03-28

    Predicting protein function has become increasingly demanding in the era of next generation sequencing technology. The task to assign a curator-reviewed function to every single sequence is impracticable. Bioinformatics tools, easy to use and able to provide automatic and reliable annotations at a genomic scale, are necessary and urgent. In this scenario, the Gene Ontology has provided the means to standardize the annotation classification with a structured vocabulary which can be easily exploited by computational methods. Argot2 is a web-based function prediction tool able to annotate nucleic or protein sequences from small datasets up to entire genomes. It accepts as input a list of sequences in FASTA format, which are processed using BLAST and HMMER searches vs UniProKB and Pfam databases respectively; these sequences are then annotated with GO terms retrieved from the UniProtKB-GOA database and the terms are weighted using the e-values from BLAST and HMMER. The weighted GO terms are processed according to both their semantic similarity relations described by the Gene Ontology and their associated score. The algorithm is based on the original idea developed in a previous tool called Argot. The entire engine has been completely rewritten to improve both accuracy and computational efficiency, thus allowing for the annotation of complete genomes. The revised algorithm has been already employed and successfully tested during in-house genome projects of grape and apple, and has proven to have a high precision and recall in all our benchmark conditions. It has also been successfully compared with Blast2GO, one of the methods most commonly employed for sequence annotation. The server is freely accessible at http://www.medcomp.medicina.unipd.it/Argot2.

  9. Adaptability of the Saccharomyces cerevisiae yeasts to wine fermentation conditions relies on their strong ability to consume nitrogen.

    Science.gov (United States)

    Brice, Claire; Cubillos, Francisco A; Dequin, Sylvie; Camarasa, Carole; Martínez, Claudio

    2018-01-01

    Saccharomyces cerevisiae strains are genetically diverse, largely as a result of human efforts to develop strains specifically adapted to various fermentation processes. These adaptive pressures from various ecological niches have generated behavioral differences among these strains, particularly in terms of their nitrogen consumption capacities. In this work, we characterize this phenotype by the specific quantity of nitrogen consumed under oenological fermentation conditions using a new approach. Indeed, unlike previous studies, our experiments were conducted in an environment containing excess nitrogen, eliminating the nitrogen limitation/starvation factor that is generally observed in fermentation processes. Using these conditions, we evaluated differences in the nitrogen consumption capacities for a set of five strains from diverse origins. The strains presented extremely different phenotypes and variations in their capacities to take up nitrogen from a wine fermentation environment. These variations reflect the differences in the nitrogen uptake capacities between wine and non-wine strains. Finally, the strains differed in their ability to adapt to the nitrogen composition of the environment, leading to variations in the cellular stress states, fermentation performances and the activity of the nitrogen sensing signaling pathway.

  10. Do political and economic choices rely on common neural substrates? A systematic review of the emerging neuropolitics literature

    Directory of Open Access Journals (Sweden)

    Sekoul eKrastev

    2016-02-01

    Full Text Available The methods of cognitive neuroscience are beginning to be applied to the study of political behavior. The neural substrates of value-based decision-making have been extensively examined in economic contexts; this might provide a powerful starting point for understanding political decision-making. Here, we asked to what extent the neuropolitics literature to date has used conceptual frameworks and experimental designs that make contact with the reward-related approaches that have dominated decision neuroscience. We then asked whether the studies of political behavior that can be considered in this light implicate the brain regions that have been associated with subjective value related to economic rewards. We performed a systematic literature review to identify papers addressing the neural substrates of political behavior and extracted the fMRI studies reporting behavioral measures of subjective value as defined in decision neuroscience studies of reward. A minority of neuropolitics studies met these criteria and relatively few brain activation foci from these studies overlapped with regions where activity has been related to subjective value. These findings show modest influence of reward-focused decision neuroscience on neuropolitics research to date. Whether the neural substrates of subjective value identified in economic choice paradigms generalize to political choice thus remains an open question. We argue that systematically addressing the commonalities and differences in these two classes of value-based choice will be important in developing a more comprehensive model of the brain basis of human decision-making.

  11. Do Political and Economic Choices Rely on Common Neural Substrates? A Systematic Review of the Emerging Neuropolitics Literature.

    Science.gov (United States)

    Krastev, Sekoul; McGuire, Joseph T; McNeney, Denver; Kable, Joseph W; Stolle, Dietlind; Gidengil, Elisabeth; Fellows, Lesley K

    2016-01-01

    The methods of cognitive neuroscience are beginning to be applied to the study of political behavior. The neural substrates of value-based decision-making have been extensively examined in economic contexts; this might provide a powerful starting point for understanding political decision-making. Here, we asked to what extent the neuropolitics literature to date has used conceptual frameworks and experimental designs that make contact with the reward-related approaches that have dominated decision neuroscience. We then asked whether the studies of political behavior that can be considered in this light implicate the brain regions that have been associated with subjective value related to "economic" reward. We performed a systematic literature review to identify papers addressing the neural substrates of political behavior and extracted the fMRI studies reporting behavioral measures of subjective value as defined in decision neuroscience studies of reward. A minority of neuropolitics studies met these criteria and relatively few brain activation foci from these studies overlapped with regions where activity has been related to subjective value. These findings show modest influence of reward-focused decision neuroscience on neuropolitics research to date. Whether the neural substrates of subjective value identified in economic choice paradigms generalize to political choice thus remains an open question. We argue that systematically addressing the commonalities and differences in these two classes of value-based choice will be important in developing a more comprehensive model of the brain basis of human decision-making.

  12. If the results of an article are noteworthy, read the entire article; do not rely on the abstract alone.

    Science.gov (United States)

    Dal-Ré, R; Castell, M V; García-Puig, J

    2015-11-01

    Clinicians typically update their knowledge by reading articles on the Internet. Easy access to the articles' abstracts and a lack of time to access other information sources creates a risk that therapeutic or diagnostic decisions will be made after reading just the abstracts. Occasionally, however, the abstracts of articles from clinical trials that have not obtained statistically significant differences in the primary study endpoint have reported other positive results, for example, of a secondary endpoint or a subgroup analysis. The article, however, correctly reports all results, including those of the primary endpoint. In the abstract, the safety information of the experimental treatment is usually deficient. The whole article should be read if a clinical decision is to be made. Copyright © 2015 Elsevier España, S.L.U. y Sociedad Española de Medicina Interna (SEMI). All rights reserved.

  13. The walking-induced transient hack concept is valid & relies on a transient early-exercise hypoxemia.

    Directory of Open Access Journals (Sweden)

    Antoine Bruneau

    Full Text Available Decreased arterial oxygen pressure obtained at peak exercise is strong evidence of walking-induced hypoxemia, assuming that the lower pressure occurs just before exercise is stopped. Using empirical predefined models and transcutaneous oximetry, we have shown that some patients reporting exercise intolerance show a minimal value at the onset of walking and a post-exercise overshoot. These changes are referred to as transcutaneous "walking-induced transient hacks".In 245 patients, walking-induced transcutaneous oxygen pressure changes in the chest were analyzed using observer-independent clustering techniques. Clustering classes were compared to the profile types previously proposed with the cross-correlation technique. The classifications of patients according to both approaches were compared using kappa statistics. In 10 patients showing a hack on transcutaneous oximetry, we analyzed the results of direct iterative arterial sampling recorded during a new walking treadmill test.Clustering analysis resulted in 4 classes that closely fit the 4 most frequently proposed empirical models (cross-correlation coefficients: 0.93 to 0.97. The kappa between the two classifications was 0.865. In 10 patients showing transcutaneous hacks, the minimal direct arterial oxygen pressure value occurred at exercise onset, and these patients exhibited a recovery overshoot reaching a maximum at two minutes of recovery, confirming the walking-induced transient hypoxemia.In patients reporting exercise intolerance, transcutaneous oximetry could help to detect walking-induced transient hypoxemia, while peak-exercise arterial oximetry might be normal.

  14. Immigrant and Refugee Students across "Receiving" Nations: To What Extent Can Educators Rely on PISA for Answers?

    Science.gov (United States)

    Rubinstein-Avila, Eliane

    2016-01-01

    Massive population shift is a current global reality--especially given some of the latest development on European shores; some are calling it a humanitarian crisis. Although the United States (US) receives a large number of immigrants (documented and not) and about 70,000 refugees each year, it is certainly not the only nation to do so.…

  15. Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division.

    Science.gov (United States)

    Bohineust, Armelle; Garcia, Zacarias; Beuneu, Hélène; Lemaître, Fabrice; Bousso, Philippe

    2018-05-07

    T cells are primed in secondary lymphoid organs by establishing stable interactions with antigen-presenting cells (APCs). However, the cellular mechanisms underlying the termination of T cell priming and the initiation of clonal expansion remain largely unknown. Using intravital imaging, we observed that T cells typically divide without being associated to APCs. Supporting these findings, we demonstrate that recently activated T cells have an intrinsic defect in establishing stable contacts with APCs, a feature that was reflected by a blunted capacity to stop upon T cell receptor (TCR) engagement. T cell unresponsiveness was caused, in part, by a general block in extracellular calcium entry. Forcing TCR signals in activated T cells antagonized cell division, suggesting that T cell hyporesponsiveness acts as a safeguard mechanism against signals detrimental to mitosis. We propose that transient unresponsiveness represents an essential phase of T cell priming that promotes T cell disengagement from APCs and favors effective clonal expansion. © 2018 Bohineust et al.

  16. Catalytic ozonation not relying on hydroxyl radical oxidation: A selective and competitive reaction process related to metal-carboxylate complexes

    KAUST Repository

    Zhang, Tao; Croue, Jean-Philippe

    2014-01-01

    Catalytic ozonation following non-hydroxyl radical pathway is an important technique not only to degrade refractory carboxylic-containing organic compounds/matter but also to avoid catalyst deactivation caused by metal-carboxylate complexation

  17. Relying on satiety cues in food consumption : studies on the role of social context, appearance focus, and mindfulness

    NARCIS (Netherlands)

    Veer, van de E.

    2013-01-01

    Consumers eat at various sequential occasions throughout the day. The current thesis addresses the question of how one consumption episode can affect the amount of consumption at a subsequent episode. The thesis focuses specifically on how the social context during a consumption episode affects

  18. Interpersonal rejection results in increased appearance satisfaction for women who rely on body weight for self-worth.

    Science.gov (United States)

    O'Driscoll, Lauren M; Jarry, Josée L

    2015-01-01

    This study examined whether body weight contingent self-worth (BWCSW), the tendency to base self-worth on body weight, moderates the effects of interpersonal rejection on self-esteem and body satisfaction. In an online survey, female undergraduates (N=148) completed measures of trait self-esteem, depression, and BWCSW. In a subsequent lab session, participants were assigned to either an interpersonal rejection or to a neutral control condition, after which they completed measures of state self-esteem and body satisfaction. Compared to women with lower BWCSW, women with higher BWCSW reported lower appearance self-esteem (p=.001) and body satisfaction (p=.004) across conditions. However, they reacted to rejection by reporting greater appearance self-esteem (p=.034) and body satisfaction (p=.021). Rejection had no effect on women with lower BWCSW. The reaction of women with higher BWCSW is interpreted as a compensatory self-enhancement response to interpersonal rejection within a self-important domain. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Do Political and Economic Choices Rely on Common Neural Substrates? A Systematic Review of the Emerging Neuropolitics Literature

    Science.gov (United States)

    Krastev, Sekoul; McGuire, Joseph T.; McNeney, Denver; Kable, Joseph W.; Stolle, Dietlind; Gidengil, Elisabeth; Fellows, Lesley K.

    2016-01-01

    The methods of cognitive neuroscience are beginning to be applied to the study of political behavior. The neural substrates of value-based decision-making have been extensively examined in economic contexts; this might provide a powerful starting point for understanding political decision-making. Here, we asked to what extent the neuropolitics literature to date has used conceptual frameworks and experimental designs that make contact with the reward-related approaches that have dominated decision neuroscience. We then asked whether the studies of political behavior that can be considered in this light implicate the brain regions that have been associated with subjective value related to “economic” reward. We performed a systematic literature review to identify papers addressing the neural substrates of political behavior and extracted the fMRI studies reporting behavioral measures of subjective value as defined in decision neuroscience studies of reward. A minority of neuropolitics studies met these criteria and relatively few brain activation foci from these studies overlapped with regions where activity has been related to subjective value. These findings show modest influence of reward-focused decision neuroscience on neuropolitics research to date. Whether the neural substrates of subjective value identified in economic choice paradigms generalize to political choice thus remains an open question. We argue that systematically addressing the commonalities and differences in these two classes of value-based choice will be important in developing a more comprehensive model of the brain basis of human decision-making. PMID:26941703

  20. Early CT perfusion mismatch in acute stroke is not time-dependent but relies on collateralization grade

    Energy Technology Data Exchange (ETDEWEB)

    Baumgarten, Louisa von; Straube, Andreas [University of Munich Hospitals, Department of Neurology, Munich (Germany); Thierfelder, Kolja M.; Beyer, Sebastian E.; Baumann, Alena B.; Bollwein, Christine; Reiser, Maximilian F.; Sommer, Wieland H. [Ludwig-Maximilians-University Hospital Munich, Institute for Clinical Radiology, Munich (Germany); Janssen, Hendrik [Ludwig-Maximilians-University Hospital Munich, Department of Neuroradiology, Munich (Germany)

    2016-04-15

    Factors that determine the extent of the penumbra in the initial diagnostic workup using whole brain CT Perfusion (WB-CTP) remain unclear. The purpose of the current study was to determine a possible dependency of the initial mismatch size between cerebral blood flow (CBF) and cerebral blood volume (CBV) from time after symptom onset, leptomeningeal collateralization, and occlusion localization in acute middle cerebral artery (MCA) infarctions. Out of an existing cohort of 992 consecutive patients receiving multiparametric CT scans including WB-CTP due to suspected stroke, we included patients who had (1) a witnessed time of symptom onset, (2) an infarction of the MCA territory as documented by follow-up imaging, and (3) an initial CBF volume of >10 ml. CBF and CBV lesion sizes, collateralization grade, and the site of occlusion were determined. We included 103 patients. Univariate analysis showed that time from symptom onset (168 +/- 91.2 min) did not correlate with relative or absolute mismatch volumes (p = 0.458 and p = 0.921). Higher collateralization gradings were associated with small absolute mismatch volumes (p = 0.004 and p < 0.001). Internal carotid artery (ICA) occlusions were associated with large absolute mismatch volumes (p = 0.004). Multivariate analysis confirmed that ICA occlusion was associated with large absolute mismatch volumes (p = 0.005), and high collateral grade was associated with small absolute mismatch volumes (p = 0.017). There is no significant correlation between initial CTP mismatch and time after symptom onset. Predictors of mismatch size include the extent of the collaterals and a proximal location of the occlusion. (orig.)

  1. We could learn much more from 1918 pandemic-the (mis)fortune of research relying on original death certificates.

    Science.gov (United States)

    Alonso, Wladimir J; Nascimento, Francielle C; Chowell, Gerardo; Schuck-Paim, Cynthia

    2018-05-01

    The analysis of historical death certificates has enormous potential for understanding how the health of populations was shaped by diseases and epidemics and by the implementation of specific interventions. In Brazil, the systematic archiving of mortality records was initiated only in 1944-hence the analysis of death registers before this time requires searching for these documents in public archives, notaries, parishes, and especially ancient cemeteries, which are often the only remaining source of information about these deaths. This article describes an effort to locate original death certificates in Brazil and document their organization, accessibility, and preservation. To this end, we conducted an exploratory study in 19 of the 27 Brazilian states, focusing on the period surrounding the 1918 influenza pandemic (1913-1921). We included 55 cemeteries, 22 civil archives, and one military archive. Apart from few exceptions, the results show the absence of a curatorial policy for the organization, access or even physical preservation of this material, frequently leading to unavailability, deterioration, and ultimately its complete loss. This study indicates the need to promote the preservation of a historical heritage that is a key to understanding historical epidemiological patterns and human responses to global health threats. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. So you want to work? What employers say about job skills, recruitment and hiring employees who rely on AAC.

    Science.gov (United States)

    Bryen, Diane Nelson; Potts, Blyden B; Carey, Allison C

    2007-06-01

    In order to better understand employer perspectives with respect to hiring and working with people who use AAC and the kinds of employment barriers they believe exist for these individuals, a study into the job requirements, recruitment processes, and hiring processes of 27 employers in the United States was conducted. Interviews with the 27 employers focused on 48 jobs in 25 unique categories, many of which had previously been identified as desirable by 38 adults who used AAC (some of whom were employed and some of whom were seeking employment). Findings suggest that, while level of education is still important to employers, skills such as time management, problem solving, communication, use of an understandable and standard voice, and basic technology may be even more so. The study also found that having an effective job-related network is important, as is the ability to provide credible references and do well during in-person interviews with potential employers.

  3. Development of a millimetrically scaled biodiesel transesterification device that relies on droplet-based co-axial fluidics

    Science.gov (United States)

    Yeh, S. I.; Huang, Y. C.; Cheng, C. H.; Cheng, C. M.; Yang, J. T.

    2016-07-01

    In this study, we investigated a fluidic system that adheres to new concepts of energy production. To improve efficiency, cost, and ease of manufacture, a millimetrically scaled device that employs a droplet-based co-axial fluidic system was devised to complete alkali-catalyzed transesterification for biodiesel production. The large surface-to-volume ratio of the droplet-based system, and the internal circulation induced inside the moving droplets, significantly enhanced the reaction rate of immiscible liquids used here - soybean oil and methanol. This device also decreased the molar ratio between methanol and oil to near the stoichiometric coefficients of a balanced chemical equation, which enhanced the total biodiesel volume produced, and decreased the costs of purification and recovery of excess methanol. In this work, the droplet-based co-axial fluidic system performed better than other methods of continuous-flow production. We achieved an efficiency that is much greater than that of reported systems. This study demonstrated the high potential of droplet-based fluidic chips for energy production. The small energy consumption and low cost of the highly purified biodiesel transesterification system described conforms to the requirements of distributed energy (inexpensive production on a moderate scale) in the world.

  4. Polyploid species rely on vegetative reproduction more than diploids: a re-examination of the old hypothesis

    Czech Academy of Sciences Publication Activity Database

    Herben, Tomáš; Suda, Jan; Klimešová, Jitka

    2017-01-01

    Roč. 120, č. 2 (2017), s. 341-349 ISSN 0305-7364 R&D Projects: GA ČR(CZ) GA16-19245S Institutional support: RVO:67985939 Keywords : phylogenetic analysis * clonal traits * correlated evolution Subject RIV: EF - Botanics OBOR OECD: Plant sciences, botany Impact factor: 4.041, year: 2016

  5. Catalytic ozonation of oxalate with a cerium supported palladium oxide: An efficient degradation not relying on hydroxyl radical oxidation

    KAUST Repository

    Zhang, Tao

    2011-11-01

    The cerium supported palladium oxide (PdO/CeO 2) at a low palladium loading was found very effective in catalytic ozonation of oxalate, a probe compound that is difficult to be efficiently degraded in water with hydroxyl radical oxidation and one of the major byproducts in ozonation of organic matter. The oxalate was degraded into CO 2 during the catalytic ozonation. The molar ratio of oxalate degraded to ozone consumption increased with increasing catalyst dose and decreasing ozone dosage and pH under the conditions of this study. The maximum molar ratio reached around 1, meaning that the catalyst was highly active and selective for oxalate degradation in water. The catalytic ozonation, which showed relatively stable activity, does not promote hydroxyl radical generation from ozone. Analysis with ATR-FTIR and in situ Raman spectroscopy revealed that 1) oxalate was adsorbed on CeO 2 of the catalyst forming surface complexes, and 2) O 3 was adsorbed on PdO of the catalyst and further decomposed to surface atomic oxygen (*O), surface peroxide (*O 2), and O 2 gas in sequence. The results indicate that the high activity of the catalyst is related to the synergetic function of PdO and CeO 2 in that the surface atomic oxygen readily reacts with the surface cerium-oxalate complex. This kind of catalytic ozonation would be potentially effective for the degradation of polar refractory organic pollutants and hydrophilic natural organic matter. © 2011 American Chemical Society.

  6. Number and density discrimination rely on a common metric: Similar psychophysical effects of size, contrast, and divided attention.

    Science.gov (United States)

    Tibber, Marc S; Greenwood, John A; Dakin, Steven C

    2012-06-04

    While observers are adept at judging the density of elements (e.g., in a random-dot image), it has recently been proposed that they also have an independent visual sense of number. To test the independence of number and density discrimination, we examined the effects of manipulating stimulus structure (patch size, element size, contrast, and contrast-polarity) and available attentional resources on both judgments. Five observers made a series of two-alternative, forced-choice discriminations based on the relative numerosity/density of two simultaneously presented patches containing 16-1,024 Gaussian blobs. Mismatches of patch size and element size (across reference and test) led to bias and reduced sensitivity in both tasks, whereas manipulations of contrast and contrast-polarity had varied effects on observers, implying differing strategies. Nonetheless, the effects reported were consistent across density and number judgments, the only exception being when luminance cues were made available. Finally, density and number judgment were similarly impaired by attentional load in a dual-task experiment. These results are consistent with a common underlying metric to density and number judgments, with the caveat that additional cues may be exploited when they are available.

  7. Mast cell tryptase stimulates myoblast proliferation; a mechanism relying on protease-activated receptor-2 and cyclooxygenase-2

    Directory of Open Access Journals (Sweden)

    Côté Claude H

    2011-10-01

    Full Text Available Abstract Background Mast cells contribute to tissue repair in fibrous tissues by stimulating proliferation of fibroblasts through the release of tryptase which activates protease-activated receptor-2 (PAR-2. The possibility that a tryptase/PAR-2 signaling pathway exists in skeletal muscle cell has never been investigated. The aim of this study was to evaluate whether tryptase can stimulate myoblast proliferation and determine the downstream cascade. Methods Proliferation of L6 rat skeletal myoblasts stimulated with PAR-2 agonists (tryptase, trypsin and SLIGKV was assessed. The specificity of the tryptase effect was evaluated with a specific inhibitor, APC-366. Western blot analyses were used to evaluate the expression and functionality of PAR-2 receptor and to assess the expression of COX-2. COX-2 activity was evaluated with a commercial activity assay kit and by measurement of PGF2α production. Proliferation assays were also performed in presence of different prostaglandins (PGs. Results Tryptase increased L6 myoblast proliferation by 35% above control group and this effect was completely inhibited by APC-366. We confirmed the expression of PAR-2 receptor in vivo in skeletal muscle cells and in satellite cells and in vitro in L6 cells, where PAR-2 was found to be functional. Trypsin and SLIGKV increased L6 cells proliferation by 76% and 26% above control, respectively. COX-2 activity was increased following stimulation with PAR-2 agonist but its expression remained unchanged. Inhibition of COX-2 activity by NS-398 abolished the stimulation of cell proliferation induced by tryptase and trypsin. Finally, 15-deoxy-Δ-12,14-prostaglandin J2 (15Δ-PGJ2, a product of COX-2-derived prostaglandin D2, stimulated myoblast proliferation, but not PGE2 and PGF2α. Conclusions Taken together, our data show that tryptase can stimulate myoblast proliferation and this effect is part of a signaling cascade dependent on PAR-2 activation and on the downstream activation of COX-2.

  8. Mobiliser les canadiens pour accroître l' impact | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    14 déc. 2010 ... L'objectif : trouver des solutions concrètes aux problèmes reliés à la santé et aux services de santé dans les pays à faible revenu et les pays à revenu ... ils recevront un financement de base à long terme, qui leur permettra de recruter et de garder des chercheurs de haut niveau et qui viendra améliorer la ...

  9. Reconnecter l’humain et la nature

    OpenAIRE

    Brunelle, Charles-Mathieu

    2013-01-01

    Qu’est-ce qui n’a pas été fait pour la nature ? À partir de cette interrogation en forme de constat, les responsables de l’Espace pour la vie – qui rassemble les institutions muséales des sciences de la Nature de Montréal et la Grande Place qui les relie – multiplient les initiatives pour rétablir le contact entre l’homme et la nature et impliquer davantage les citoyens dans la protection de la biodiversité.

  10. C'est le Ton Qui Fait la Critique—for the powerful: the effects of feedback framing and power on affective reactions

    NARCIS (Netherlands)

    Niemann, Jana; Wisse, Barbara; Rus, Diana; Van Yperen, Nico W.; Sassenberg, Kai

    2014-01-01

    Although negative feedback is usually provided with the best of intentions, it often causes unfavorable affective reactions in the receiver such as anger and shame. The purpose of the present research is to identify factors that may attenuate or intensify these reactions to negative feedback. We

  11. La atención del parto en Chiapas, México: ¿dónde y quién los atiende

    Directory of Open Access Journals (Sweden)

    Sánchez-Pérez Héctor Javier

    1998-01-01

    Full Text Available Objetivo. Identificar el sitio y el agente de atención del parto; analizar el agente de atención del parto según la atención prenatal (AP y factores sociodemográficos; identificar grupos con menor y mayor probabilidad de recibir atención por parte del personal de los servicios de salud; identificar los motivos de no atenderse en la unidad de salud más cercana al domicilio. Material y métodos. Se analizan datos sobre la atención del parto en 297 mujeres de la Región Fraylesca (Chiapas, usando modelos logit para la identificación de grupos. Resultados. El 32% de los partos ocurrieron en instituciones de salud, y 60%, en el hogar (mayoritariamente en condiciones higiénico-sanitarias desfavorables. Sólo 10% del grupo de mujeres con menos de cinco consultas de AP, una escolaridad menor al tercero de primaria y un jefe de hogar dedicado a labores agropecuarias, fue atendido por personal de salud. Conclusiones. Es necesario mejorar la cobertura, la aceptabilidad y la calidad de los servicios de salud e instrumentar un programa dirigido a incrementar el número de partos en condiciones higiénico-sanitarias adecuadas.

  12. ¿Centinela? Alerta. ¿Quién Vive? Colombia. El carácter Militar de Ia Guardia Colombiana (1863 -1885

    Directory of Open Access Journals (Sweden)

    Saúl Mauricio Rodríguez Hernández

    2004-06-01

    Full Text Available This article studies the institutional characteristics of the Guardia Colombiana which were the armed forces during the time-period of the Constitution of the Estados Unidos de Colombia (1863-1885. This armed force was created with a "civil'' character to avoid the abuses of the troops. But it conserved certain key elements such as hierarchy of rank, uniforms, military instruction, internal structure, etc. I discuss the possibility that the Guardia Colombiana can be located within the so-called "pre-professional armed forces". It did not, how¬ever, form the base of the modern national army.//Este artículo estudia las características institucionales de la Guardia Colombiana. Fuerza armada al servicio del Estado durante la vigencia de la Constitución de los Estados Unidos de Colombia (1863-1885. Analizando cómo esta fuerza armada creada con un carácter ''civil" para evitar los desmanes de la tropa, conserve elementos propiamente militares que la equiparan con un ejército (jerarquía de los rangos, uniformes, instrucción militar, estructura interna, entre otros. Se discute la posibilidad que tiene la Guardia Colombiana, para ubicarse dentro de las denominadas "fuerzas armadas pre-profesionales", y la imposibilidad para que fuera utilizada como base para crear un ejército nacional moderno.

  13. DE LA VILLE PERÇUE À LA VILLE QUI PERÇOIT: GYÖRGY KEPES ET LA SMART CITY

    Directory of Open Access Journals (Sweden)

    Bolay, Jean-Marie

    2015-06-01

    Full Text Available This paper will address thequestion of aesthetic road design in relation with the psychology of the perception, in the United States during the second half of the twentieth century. Taking the work of the artist and theoretician Gyorgy Kepes (1906‐ 2001 as a starting point, I propose to discuss the evolution of urbanism, from a gestalt informed perspective to a cybernetic one, which anticipated the emergence of the concept of smart city.

  14. Trente années qui ébranlèrent la physique histoire de la théorie quantique

    CERN Document Server

    Gamow, George

    1968-01-01

    G. Gamow, dans cet ouvrage, déploie une fois encore ses qualités d'historien, de vulgarisateur et d'homme d'esprit. L'"histoire de la théorie quantique" raconte la naissance de la physique moderne au cours des trente premières années du siècle, en nous guidant ainsi à travers cette galerie de portraits où les grands noms de la physique sont présentés, par les textes, les photographies et les croquis, sous leur aspect le moins académique.

  15. El arzobispo don Pedro de Castro Cabeza de Vaca y Quiñones y la influencia del Sacro Monte en el desarrollo inmaculista en Granada.

    Directory of Open Access Journals (Sweden)

    José Antonio Peinado Guzmán

    2015-12-01

    Full Text Available The figure of archbishop don Pedro de Castro was extremely important for the development of immaculist devotion in Granada in the 16th century and beginning of the 17th century. In the wake of the famous discoveries of the Sacro Monte, it will produce an evolution of this belief in land Granada at the request of this prelate, who took the issue as one of his personal priorities in his episcopate. Intelligent handling of the issue by the Archbishop, while the findings of the Sacro Monte were subsequently convicted of Rome, eventually landing in the erection of the Abbey, in the ideological use of all of this, as well as the extension of the conceptionism in Granada.

  16. ¿Quién programa las redes sociales en Internet? El caso de Twiter en el movimiento #Yosoy132 México

    Directory of Open Access Journals (Sweden)

    Torres Nabel, Luis César

    2015-08-01

    Full Text Available The article discusses the latest hypothesis that social networks and Internet social influence is spontaneous and accidental, which contradicts the old hypothesis of the initial programming of all social movements from a previously defined strategic influence. The discussion starts from analyzing of the most influential players in the movement #YoSoy132 on social network Twitter in México.El artículo discute las últimas hipótesis de que en las redes sociales e Internet la influencia social es espontánea y accidental, lo que contradice las viejas hipótesis de la programación inicial de todo movimiento social a partir de un ejercicio de influencia estratégica y previamente definida. La discusión parte del análisis de los actores más influyentes en el movimiento #YoSoy132 en la red social Twitter en México.

  17. ¿Quién teme al lector feroz? Sin título, de Hervé Tullet, y las convenciones del cuento clásico

    Directory of Open Access Journals (Sweden)

    Leonor Ruiz Guerrero

    2018-01-01

    Full Text Available El cuento clásico o tradicional ha sido uno de los cimientos principales en los que ha sustentado su desarrollo el género álbum ilustrado. Partiendo de esta premisa, el objetivo del presente trabajo ha sido analizar la relación entre el cuento clásico y el álbum ilustrado postmoderno, en el caso concreto de una obra radicalmente metaficcional: Sin título, de Hervé Tullet (2013. Para llevar a cabo el análisis se han considerado instrumentos ya existentes, como los de Propp (1927, Silva-Díaz (2005 o Goldstone (2002. No obstante, al no tratarse de un texto narrativo propiamente dicho, las categorías se han extraído de la propia obra. Los resultados del análisis muestran el fuerte vínculo existente entre los dos géneros, aunque no se trata de una mera transposición de elementos, sino de todo un trabajo reflexivo y creativo

  18. Dime quién lo define y te diré si es violento. Reflexiones sobre la violencia obstétrica

    Directory of Open Access Journals (Sweden)

    Belén Castrillo

    Full Text Available Resumen: La propuesta de trabajo es problematizar la definición de la violencia obstétrica (VO, que nace en ciertas prácticas y relaciones en la atención médica de partos. Para ello se proponen dos ejes de trabajo interrelacionados: primero, la aplicación de un modelo de análisis socioantropológico de la violencia a lo específico de la VO; segundo, el cruce entre definiciones objetivas (legales, políticas y académicas y subjetivas (a raíz de un documento producido por asociaciones de la sociedad civil para abordar tal problematización. Partimos del supuesto de que subyace en la definición de VO un campo de disputa por las legitimidades (de su definición, en una interrelación constante entre las nominaciones objetivas y las significaciones subjetivas sobre ciertas prácticas obstétricas, definidas como violentas. Sostenemos que el cambio en las sensibilidades sociales sobre diversas formas de violencia (que generó cambios en las legitimidades explica la actual discusión sobre la definición de la VO.

  19. Alfred Loisy, más allá del ruido y del humo. «Qui perdiderit animan suam salvam faciet eam (Marc, VIII, 35

    Directory of Open Access Journals (Sweden)

    Robles Muñoz, Cristobal

    2007-12-01

    Full Text Available Loisy and the modernism were identified during years. This work tries, beyond the noise and the smoke, to contribute not to loose in the forgetfulness neither the person nor the reasons of Alfred Loisy, one of the most affected by the modernist crisis. We have resorted mainly to his Mémoires. Loisy did not need to hope years to receive the tribute that deserves a person who has not betrayed itself.Loisy y el modernismo se identicaron durante años. Este trabajo pretende, más allá del ruido y del humo, contribuir a que no se pierda en el olvido ni la persona ni las razones de Alfred Loisy, uno de los más afectados por la crisis modernista. Hemos recurrido sobre todo a a sus Mémoires. Loisy no necesitó esperar años para recibir el homenaje que merece una persona que no se ha traicionado.

  20. ¿Quién necesita una lengua? Política y planificación lingüística en el departamento del Cauca

    OpenAIRE

    Geny Gonzales Castaño

    2012-01-01

    El propósito de este artículo es realizar una reflexión acerca de la forma en la cual las motivaciones políticas que trazan los límites y condiciones de la planificación lingüística hoy, se establecen en relación con las políticas de reconocimiento y administración de la diversidad cultural y lingüística por parte del estado colombiano. Para este fin me centraré en el caso del proceso de fortalecimiento de lengua nam trik o namuy wam, hablada en el departamento del Cauca.

  1. Regulations concerning radiation protection and survey; Donnees de la surveillance et regles qui en resultent en matiere de protection contre les rayonnements

    Energy Technology Data Exchange (ETDEWEB)

    Duhamel,; Lavie,; Fitoussi, [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The many and always increasing applications of Atomic Energy for peaceful uses set many safety and security problems relatively to the workers, populations, and locating of the sites in general. A comparative study of the radiation hazards to which the people working in the 'Commissariat a l'energie atomique' installations were exposed during 1957 and the results obtained concerning individual and collective safety and security were extremely satisfactory owing to a continuous control and supervision. 2. However a few contamination and irradiation incidents - exposed subsequently as well as the way they were dealt with - show the necessity of a circumstantial regulation inside of an atomic center to establish the responsibility of the service in charge of the control of the radiation and the responsibility of the services using radioactive products with regard to contamination by radioactive materials. 3. Abstract of the different practical safety and security regulations concerning holding, manipulation, transport and stocking of radioactive materials. Pursuant to the recommendations of the International Commission on Radiologic Protection, the radioelements are classified according to the danger that can occur from them in comparison with the Pu with regard to: - radioactive noxiousness; specific activity per unit of mass; contamination hazards. 4. The service in charge of radiation protection plays the important part of a technical adviser for the construction of specialized laboratories and sees to the keeping of protection regulations. 5. Data essential to radiation protection are given to the people using radioactive materials; particularly: - a table of the radioisotopes and the hazards occurring from them; - radiation hazards regarding {gamma} ray emitted by irradiated Pu; - radiation hazards regarding {gamma} ray emitted by irradiated Th. 6. As the hazards occasioned by irradiated uranium have already been studied, the case of a low and total irradiation will only be considered with regard to recuperation of uranium after simple machining. (author) [French] 1. L'utilisation croissante de l'energie nucleaire sous toutes ses formes a des fins pacifiques pose des problemes de securite vis-a-vis des travailleurs, des populations et des sites en general. Une etude comparee des risques d'irradiation auxquels le personnel du Commissariat a l'Energie atomique (CEA) a ete expose au cours de l'annee 1957 et des resultats du controle des radiations par les moyens de detection collectifs ou individuels montre que les installations du CEA ont une influence negligeable sur la sante, en raison de la surveillance exercee. 2. Cependant, quelques incidents de contamination et d'irradiation - sommairement indiques ainsi que la maniere dont ils ont ete regles - rendent necessaire l'elaboration d'une reglementation precise definissant les responsabilites respectives, au sein d'un etablissement nucleaire, des services utilisateurs et du Service charge de la Protection contre les Radiations, en matiere de prevention de la contamination. 3. Un ensemble coherent de regles pratiques de prevention et de protection relatives a la detention, la manipulation, le transport et le stockage de sources radioactives scellees ou non scellees, est presente. A cette fin, a partir des recommandations de la Commission Internationale de Protection Radiologique et compte tenu: - de leur nocivite radioactive; de leur activite specifique par unite de masse et du risque de contamination; les radioelements ont ete classes suivant le danger qu'ils presentent par rapport au plutonium. 4. Le Service charge de la Protection contre les Radiations intervient comme conseiller des la conception des laboratoires specialises et veille ensuite a ce que les prescriptions reglementaires de securite soient observees. 5. Des donnees elaborees, indispensables a la protection contre les rayonnements, sont mises a la disposition des utilisateurs en particulier: - table des radio-isotopes et des dangers associes, - danger d'irradiation {gamma} par le plutonium irradie, - danger d'irradiation {gamma} par le thorium irradie. 6. Le danger de l'uranium irradie ayant deja fait l'objet d'etudes, le cas d'une faible irradiation totale est specialement envisage en vue d'une reutilisation de l'uranium par simple usinage. (auteur)

  2. Cuando las víctimas de violencia escolar se convierten en agresores: “¿Quién va a defenderme?”

    Directory of Open Access Journals (Sweden)

    Estefanía Estévez

    2010-12-01

    Full Text Available Estudios previos han identificado dos subgrupos de víctimas de violencia escolar: víctimas sumisas y víctimas agresivas. Las víctimas sumisas se caracterizan por su retraimiento ante la situación de violencia, mientras que las víctimas agresivas presentan un comportamiento hostil combinado con la situación de victimización. El presente estudio se centra en el segundo subgrupo y tiene como objetivo analizar posibles factores influyentes en el proceso que conduce del estado de victimización a la implicación en conductas agresivas en la escuela. La asunción de partida se fundamenta en la teoría de Emler que sostiene que el sentimiento de indefensión producido por la situación de victimización, junto con la decepción en las figuras adultas de autoridad ante su fracaso en la protección esperada, generan en el adolescente la necesidad de buscar una reputación antisocial y no conformista que le permita defenderse de los ataques venideros. Para poner a prueba estas relaciones, se ha utilizado una muestra compuesta por 1.319 adolescentes de entre 12 y 16 años. Los análisis estadísticos mediante un modelo de ecuaciones estructurales muestran resultados en la línea de la argumentación de Emler. En la discusión se comentan las implicaciones prácticas de estos resultados

  3. Grand résumé de Ce qui circule entre nous. Donner, recevoir, rendre, Paris, Éditions du Seuil, 2007

    Directory of Open Access Journals (Sweden)

    Jacques T. Godbout

    2011-04-01

    Full Text Available « Surtout méfions-nous, Messieurs, de nos premiers mouvements, disait un diplomate à ses pairs, ils sont presque toujours bons » (Friedrich Nietzsche, Généalogie de la morale, 1996, p. 158, souligné par lui.L’étude du don comme phénomène social a été pratiquement abandonnée aux ethnologues pendant une grande partie du xxème siècle. Dans L’Esprit du don, publié d’abord en 1992 (Godbout & Caillé, 1992, nous soutenions la thèse que le don demeure un phénomène fondamental. Aujourd’hui, le don e...

  4. Ces silences de la narration qui rapprochèrent Jean Giono et Juan Ramón Jiménez

    Directory of Open Access Journals (Sweden)

    Dominique Bonnet

    2010-01-01

    Full Text Available This article intends to show how JeanGiono discovered a purity of writing inJuan Ramón Jiménez that he practicedhimself in his elliptical narratives. Thus,this purifying desire that both sought intheir writings would be one of the commonpoints that would persuade Jean Giono todo the film adaptation of Platero y yo.

  5. ¿Quiénes dirigen las instituciones educativas en Cali? Perfil de los directivos docentes en colegios públicos y privados de estratos 1 a 4

    Directory of Open Access Journals (Sweden)

    Norbella Miranda

    2011-12-01

    Full Text Available El objetivo de este artículo es proveer una descripción del perfil de los administradores de la educación que laboran en instituciones públicas y privadas de educación básica y media de estratos 1 a 4 en la ciudad de Santiago de Cali, a través de los rasgos demográficos, socioeconómicos, académicos y profesionales. El artículo es producto de una investigación sobre las condiciones de implementación de la política educativa colombiana Programa Nacional de Bilingüismo. Para el estudio se empleó una encuesta que fue respondida por 70 administradores escolares de 46 instituciones educativas de la ciudad. Los resultados mostraron que el perfil típico del administrador escolar corresponde a mujeres entre los 50y 60 años que tuvieron contacto con el idioma inglés durante sus estudios de básica secundaria, tienen título de Especialización como máximo nivel de formación alcanzado y cuentan con experiencia profesional superior a 11 años. Se hallaron diferencias entre los sectores público y privado: en el primero los directivos tienen un nivel más alto de formación académica y mejores salarios. Los resultados sugieren que se necesita mayor apoyo a la formación de los directivos del sector privado y un mejor reconocimiento económico a la labor desempeñada por los directivos docentes en ambos sectores.

  6. Comment choisir ce qui aura été? Réflexions sur l’optimisme prométhéen contemporain

    Directory of Open Access Journals (Sweden)

    Alexander Wilson

    2015-12-01

    Full Text Available Many have invoked the nihilism that is endemic of the age we call the anthropocene. Bernard Stiegler has articulated this sentiment by highlighting how anthropocene films are typically nihi listic, for example, Von Trier’s Melancholia. But if the age is characterized by a cultural pessi mism about the future of human kind, or again about its posthuman supersession, there is also a complementary symptom that corresponds to a strange optimism before the impasses of our age. This optimism, we find it represented in another anthropocene film: Nolan’s Interstellar. This too is a film where the protagonists are faced with a world lacking a future, a world dying under the stresses caused by the human’s exploitation of nature. Here, instead of the mantra ‘Enjoy it while it lasts’, an opposing moral is repeated: ‘Don’t go gentle into that good night, Rage, rage against the dying of the light.’ In the film, Thomas’ poem is a tribute to prometheanism; the death of the earth will not mean the end of human life, it declares, the human will surpass all the limits of its ecosystem, the constraints of space time itself, and become pure hyperdimensional intelligence. The film echoes the superstitious optimism in the promise of technology we now find at the heart of contemporary movements such as accelerationism. This paper assesses the validity of this intrumentalization of optimism, drawing from Leibniz’s concept of compossibility and the cosmological anthropic principle (observer bias.

  7. Technological utopia: political alibi, making citizen childish or brighter future; Les utopies technologiques: Alibi politique, infantilisation du citoyen ou lendemains qui chantent?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    A first set of contributions discusses the possibilities and opportunities some technological domains, innovations and concepts might give to energy: hydrogen, genetics, ITER, fourth generation nuclear reactors, decentralized photovoltaic energy in developing countries. Then, some authors propose critical and rather philosophical reflections about the blind trust in technology, about the relationship between scientists, journalists and citizens

  8. Le rôle de la sphère publique en réseau pour ce qui est de favoriser ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Una Hakika : Porter à grande échelle les solutions numériques pour la gestion des conflits au Kenya et en Birmanie. L'information erronée, qu'elle soit le fruit de rumeurs ou d'une désinformation intentionnelle, peut alimenter le conflit et exercer de profondes répercussions sur la paix, la... Voir davantageUna Hakika : Porter ...

  9. ¿Quiénes son los alumnos con aptitud sobresaliente? Análisis de diversas variables para su identificación

    Directory of Open Access Journals (Sweden)

    Blanca Ivet Chávez Soto

    2014-05-01

    Full Text Available El artículo tuvo como objetivo caracterizar las aptitudes sobresalientes en alumnos de tercero a quinto grado de primaria con relación a la edad, sexo y variables asociadas. Se trabajó en tres escuelas públicas del Distrito Federal, México. Se utilizó un muestreo no probabilístico, intencional, participaron 670 niños (Medad = 9.18, DE = .997, 356 mujeres y 314 hombres. También, colaboraron 24 docentes, 21 mujeres y 3 hombres (Medad = 43 años. Se aplicaron el Test de Matrices Progresivas Raven, Prueba de Pensamiento Creativo de Torrance, Escala de Compromiso con la Tarea, Prueba de Autoconcepto Académico y Lista de Nominación. Se identificaron 34 niños con perfil sobresaliente, quienes obtuvieron puntuaciones por encima del percentil 75 en por lo menos tres de las cinco pruebas, los cuales se distribuyeron en tres grupos de acuerdo con la cantidad de variables con estimaciones superiores. La U de Mann Whitney mostró que no había diferencia entre las variables con respecto al sexo, se observó que los niños de mayor edad eran más creativos. La prueba Kruskal-Wallis reportó diferencias significativas entre los tres grupos en la creatividad, compromiso con la tarea, autoconcepto académico y en la nominación del maestro. La correlación de Spearman mostró asociaciones positivas y significativas, entre la edad y la creatividad; y el compromiso con la tarea con el autoconcepto académico. Se concluye que los alumnos sobresalientes forman parte de un grupo heterogéneo, por lo que es necesario considerar diferentes variables para evaluarlos y determinar sus necesidades educativas. The purpose of the study was to determine the characteristics of the outstanding skills students in third through fifth grade in relation to age, sex and associated variables. The research was performed in three public schools in Mexico City, Mexico. We used an intentional non-probability sample, the trial included 670 children (Medad = 9.18, DE = .997, 356 women and 314 men; 24 teachers, 21 women and 3 men (Medad = 43 years. We applied the Raven Progressive Matrices Test, Torrance Test of Creative Thinking, Task Commitment Scale, Academic Self-concept Test and Nomination List. 34 children were identified with outstanding profile, because they obtained scores above the 75th percentile in at least three of the five tests, which were divided into three groups according to the number of variables with higher estimates. The Mann Whitney U test showed no differences between variables with respect to sex, we observed older children were more creative. The Kruskal -Wallis test reported significant differences amongst the three groups in creativity, task commitment, academic self-concept and teacher nomination. The Spearman correlation showed significant positive associations between age and creativity; and task commitment to academic self-concept. We conclude outstanding students are part of heterogeneous group, so it is necessary to evaluate them with different variables to determine their educational needs.

  10. La contratación laboral en el sector de la construcción en Colombia: ¿ventajas para quién?

    Directory of Open Access Journals (Sweden)

    Diana Carolina González Valencia

    2017-06-01

    Full Text Available El presente artículo tiene como objetivo aportar algunas reflexiones alrededor de la contratación laboral de los empleados de la construcción en Colombia. Se empleó como metodología la revisión del marco normativo actual del régimen de contratación laboral en Colombia, específicamente para el caso de empleados de la construcción; contrastando la información con otras fuentes tales como: la Cámara Colombiana de la Construcción (Camacol, Ministerio de Trabajo y la Intergremial de la Construcción y la Madera (ICM. Se concluye que en el actual sistema de contratación para empleados de la construcción vienen dándose numerosas irregularidades en los procesos inserción laboral en el sector que aumentan la informalidad y la subcontratación; cuyas desventajas recaen tanto en el empleado al ser más frecuente la vulneración de sus derechos laborales, como en las empresas constructoras, al aumentar sus gastos tanto en la subcontratación de personal como en el pago de las posibles sanciones legales ocasionadas por los desaciertos en los procesos de contratación.

  11. Ad vesice dolorem et ad eos qui urinam non faciunt (For bladder pain and when a person cannot urinate): nephrological disorders in Anglo-Saxon medicine.

    Science.gov (United States)

    D'Aronco, Maria A

    2009-01-01

    The attitude of 19th century (and even of 20th century) scholars toward medieval and, particularly, Anglo-Saxon medicine has been of severe criticism. According to them it was filled with superstition and stupidities. However, in these last fifty years research has proved that, compared with the Continent, Anglo-Saxon England was not a backwater. At the end of the ninth century, medical compendia in Old English began to appear, similar in structure and contents to the Latin dynamidia and to the Latin herbals. These medical treatises were written in the vernacular of the Anglo-Saxons, not in Latin, the western European language for all significant and valuable works on medicine. Bladder, kidney and urinating problems are mentioned throughout the Old English medical treatises together with their cures, that is remedies from herbs and animals. These texts contain no theoretical reflections, only very concise descriptions of symptoms (pain in the bladder, in the kidneys, difficulty in urinating etc.), while prognosis is limited to affirmations such as "he will heal very quickly," "soon there will be no pain," "it will soon be healed," etc. Remedies are made basically out of a body of medicinal plants and materials which can be traced to Greek and Roman medicine. The remedies from plants reflect a wide rational and practical knowledge of medicinal herbs. As a matter of fact, not only there is no amuletic use of plants, but most of the herbs that appear in these recipes have diuretic or analgesic properties and have been in use for centuries.

  12. La eficacia de las modelos delgadas vs las modelos normales en anuncios de lencería ¿Quién vende más?

    OpenAIRE

    Peña Guardia, Mariona Ariadna

    2015-01-01

    La industria de la moda ha tendit a utilitzar models excessivament primes des de l'entrada als anys 80. A partir d'aleshores, aquest patró s'ha vist com l'únic viable per anunciar productes de moda dirigits a un públic femení. En aquest estudi s'investiga si utilitzar models amb un IMCnormal incrementaria la eficàcia del anuncis de llenceria en quant a percepció de l'anunci, percepció de la marca i intenció de compra . La industria de la moda tiende a utilizar modelos excesivamente delgada...

  13. Mais qui a attrapé le bison de Higgs ? ... et autres questions que vous n'avez jamais osé poser à haute voix

    CERN Document Server

    Louapre, David

    2015-01-01

    Les premiers hommes, le Big-Bang et le boson de Higgs vous intriguent ? Vous fourmillez de questions sans toujours oser les poser à haute voix ? Ce livre est fait pour vous ! Laissez le créateur de la chaîne YouTube "Science étonnante" (près de 100 000 abonnés) vous révéler ses découvertes préférées. Vous n'avez qu'une vague idée de ce qu'est un atome ? Un gène ? Une probabilité ? Embarquez, vous en savez bien assez !

  14. Etude dynamique de l’environnement des villages romano-byzantins de Syrie du Nord ; localisation des structures parcellaires et cadastrales qui leurs sont liées

    Directory of Open Access Journals (Sweden)

    Georges Tate

    2000-05-01

    Full Text Available L’étude porte sur une région de 30.000 km2, allant de la frontière turque à Homs, et communément appelé "le Plateau Calcaire". Sept cents villages, d’époque romaine et byzantine y ont été recensés. Les objectifs Ils sont de deux types : comprendre l’histoire du peuplement, en particulier l’abondon progressif de très nombreux villages entre le 8éme et le 10ème siècle. A cette fin sont notamment indispensables les connaissances relatives, aux terroirs et aux terres arables effectivement disponi...

  15. An energy source which has come just in the nick of time; Une source d'energie qui tombe pile

    Energy Technology Data Exchange (ETDEWEB)

    Jacquemin, Ch.

    1999-12-01

    Fifty-six projects from industrialists and public research organisms have been proposed to the 'fuel cell' research and technological innovation network. Moreover, a project carried out by the French PSA/Renault car manufacturers and devoted to the development of vehicles equipped with fuel cells has been labelled by the network. This short paper summarizes the aim and organization of the fuel cell network in the French scientific and technical program. (J.S.)

  16. INFLUENCE DES TEMPERATURES OPERATIONNELLES SUR LA PERFORMANCE D’UN REFRIGERATEUR SOLAIRE A ADSORPTION QUI FONCTIONNE AVEC LE COUPLE CHARBON ACTIF-METHANOL

    OpenAIRE

    H SOUALMI; Z SAADI; A RAHMANI

    2014-01-01

    Le séchage des produits alimentaires au soleil est un moyen efficace, facile et économique pour conserver les aliments, en particulier les fruits. Le séchoir solaire est l'équipement le plus populaire pour le séchage des fruits. En raison de la nature intermittente de l'énergie solaire, le stockage de l'énergie thermique est nécessaire pour assurer un fonctionnement prolongé du séchoir. L'objectif principal de cette étude est d'évaluer l'efficacité du séchoir solaire intégré avec un lit en gr...

  17. Nécrologie: Ivan Impens (1935-2014. Celui qui ne dépasse pas son maître est un pauvre disciple

    Directory of Open Access Journals (Sweden)

    Bogaert, J.

    2014-01-01

    Full Text Available Obituary: Ivan Impens (1935-2014. Poor is the disciple who does not surpass his master. La gale sarcoptique ovine est la forme de gale la plus répandue au Nord-est algérien. Elle est due à Sarcoptes scabiei var. ovis. Une vaste enquête a été entreprise afin de déterminer la prévalence et le profil saisonnier de la maladie. Durant une période d'une année, plusieurs aspects ont été étudiés au Nord-est algérien. La prévalence moyenne de la maladie s'élevait à 12,02% sur les marchés à bestiaux de trois régions (Souk Ahras, Guelma et Tebessa. La période à haut risque s'est étalée de décembre à mars; quant au reste de l'année, le taux d'infestation est faible voire nul. L'infestation clinique a atteint 60% des cheptels de la région d'El-Tarf, et 49,5% des ovins examinés se sont révélés galeux. La maladie frappe les animaux de tout âge avec un taux d'infestation de 50,5% chez les brebis, 37% chez les agneaux et 22,3% chez les béliers. L'étude des aspects lésionnels et cliniques de la population ovine parasitée à El-Tarf a révélé que 55% d'individus présentaient une atteinte du museau, 30% montraient une extension des lésions crouteuses vers le chanfrein et le front, 10% avaient la tête totalement envahie par les croutes et uniquement 5% révélaient une extension vers les extrémités. Il semble que la charge parasitaire totale a une forte corrélation avec l'étendue des lésions.

  18. Gaz de France and cogeneration: a story which goes on; Gaz de France et la cogeneration: une histoire qui se poursuit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-09-15

    This document presents the principle of natural gas cogeneration (gas turbine and gas engine) and gives a general overview of the cogeneration market in France since 1991 and up to 2001 (development factors, results). The perspectives and opportunities of cogeneration are analyzed with respect to the development of new technologies like fuel cells (principle, advantages and future) and to the future energy markets. Follows a compilation and an analysis of French regulation texts about cogeneration systems, their connection to the power grid, and the tariffs of electricity re-purchase by Electricite de France (EdF). (J.S.)

  19. Nota de la editora y los editores invitados. Memorias del presente y del futuro: ¿cómo, para quién, para qué?

    Directory of Open Access Journals (Sweden)

    Paolo Vignolo

    2017-01-01

    El título Memorias del presente y del futuro corresponde precisamente a esta coyuntura, en la que convergen relatos de vida abortados, así como procesos históricos de amplio alcance, tácticas y estrategias de resistencia, macro- y micropolíticas. Al formular la convocatoria para el número teníamos en mente que la memoria, como acto colectivo de rememoración, articula el pasado, el presente y el futuro, y queríamos ir más allá de la noción habitual de memoria como anclada en el pasado, focalizada en una serie de hechos que se sitúan en un tiempo y un espacio que resultan significativos para alguien desde el presente. Si bien el pasado parece un país extraño al que queremos retornar, como lo ha dicho el escritor David Lowenthal (1998, igualmente, asumimos que la memoria es un ámbito de lo cotidiano. En ella se conecta temporal- y biográficamente la dimensión de la experiencia, aquello que le ha sucedido a alguien y de lo que es posible dar cuenta, a través de la narración o de los silencios, con la dimensión de la expectativa, con lo que aún no es, pero se presenta como guía de acción. Así, la memoria, si bien recoge la experiencia acumulada de dolor y esperanza, también condensa horizontes, como bien lo ha mostrado el filósofo de la historia Reinhard Koselleck (1993

  20. ¿Quién se beneficia de las certificaciones de café orgánico? El caso de los campesinos de La Sepultura, Chiapas

    Directory of Open Access Journals (Sweden)

    Iván Tlaloc Soleto Polanco

    2017-06-01

    Full Text Available El objetivo de esta investigación es valorar si la participación en programas de certificación orgánica es una herramienta exitosa para sacar de la pobreza a los pequeños productores del sur mediante la mejora de sus medios de vida y la reducción de su vulnerabilidad. Los métodos de investigación consisten en una amplia revisión de la literatura pertinente y en un estudio de caso. Los hallazgos muestran que los productores siguen siendo el eslabón más débil de la cadena de valor, al igual que ocurre con las cadenas comerciales de café convencional y, por lo tanto, no están obteniendo los beneficios esperados.

  1. ¿Quién se beneficia de las certificaciones de café orgánico? El caso de los campesinos de La Sepultura, Chiapas

    OpenAIRE

    Iván Tlaloc Soleto Polanco; Juana Cruz-Morales

    2017-01-01

    El objetivo de esta investigación es valorar si la participación en programas de certificación orgánica es una herramienta exitosa para sacar de la pobreza a los pequeños productores del sur mediante la mejora de sus medios de vida y la reducción de su vulnerabilidad. Los métodos de investigación consisten en una amplia revisión de la literatura pertinente y en un estudio de caso. Los hallazgos muestran que los productores siguen siendo el eslabón más débil de la cadena de valor, al igual que...

  2. ¿A quiénes afecta el desempleo? Análisis de la tasa de incidencia en Colombia

    Directory of Open Access Journals (Sweden)

    Andrés Felipe García

    2009-06-01

    Full Text Available The incidence rate represents a composite indicator that takes account of both thenumber of unemployed people and the average duration of employment. The analysis of this rate allows to portrait a more complete profile of those individuals who are more likely to either become unemployed or stay in such a situation. We find significant differences in the analysis of the unemployment rate and the incidence rate in Colombia, which suggests the importance of addressing certain elements underlying unemployment duration when appraising unemployment typology and policies aimed to overcome it.

  3. ¿A quiénes afecta el desempleo? análisis de la tasa de incidencia en Colombia

    OpenAIRE

    Forero R., Nohora; Garcia-Suaza, Andres; Guataquí, Juan

    2008-01-01

    El análisis de la dimensión de riesgo en el estudio del desempleo, complementa el estudio de aspectos como su tipología, la importancia de la intermediación laboral o la vulnerabilidad de ciertos grupos. En este sentido, la tasa de incidencia representa un indicador compuesto que tiene en cuenta el volumen de desempleados y la persistencia en este estado mediante la incorporación de la duración media del desempleo. El análisis de la tasa de incidencia permite caracterizar de manera más comple...

  4. ¿Quién parte y reparte? Análisis de la disposición urbana en la Cartago fenicia

    Directory of Open Access Journals (Sweden)

    Fumadó Ortega, Iván

    2013-12-01

    Full Text Available In this paper I would like to highlight the signifi cant architectural regularity which characterizes the pre-Roman archeological remains registered in Carthage. Despite having been repeatedly interpreted from a preconceived logical and spatial point of view, these remains allow us to set out that the Tyrian foundation was established in the Carthaginian peninsula according to a model that is referred to as per strigas in archaeological literature because it was documented better at the Archaic Greek colonies in Sicily. To defend this idea, I will indicate which architectonic remains make up its material basic, paying special attention to the remains found underneath the crossroads of the decumanus maximus and the cardo x-east, and I will try to summarize the state of the current issue on the urban shape of Phoenician Carthage. I will then go over several documentated examples of orthogonal land division in urban spaces from the Ancient Near East. This information will provide insight on the possible technical and practical context of Phoenician societies in the 9th and 8th centuries BC and, more specifically, the socio-political context of the Carthaginian founders. Finally, in light of these elements, I will put forward a proposal of a reconstruction of the urban layout of Phoenician Carthage as a whole.En este artículo quiero llamar la atención sobre la significativa regularidad arquitectónica que caracteriza los restos arqueológicos prerromanos registrados en Cartago. Pese a haber sido repetidas veces interpretados desde un prejuicio lógico-espacial, estos datos permiten proponer que la fundación tiria se implantó en la península cartaginesa según un modelo que, estando mejor documentado en las colonias arcaicas griegas de Sicilia, ha sido denominado per strigas por la historiografía arqueológica. Para defender esta tesis señalaré qué restos arquitectónicos le sirven de base material, con especial atención a los hallados bajo el cruce entre el decumano máximo y el cardo x este, e intentaré sintetizar el estado de la cuestión actual sobre la forma urbana de la Cartago fenicia. A continuación repasaré algunos ejemplos de segmentación ortogonal de espacios urbanos documentados en el Próximo Oriente antiguo. Ello nos ayudará a suponer cuál habría sido el contexto técnico y práctico en que vivieron las sociedades fenicias de los siglos IX-VIII a.C. y, más concretamente, el contexto sociopolítico de los fundadores de Cartago. Por último y a la luz de estos elementos, presentaré una propuesta de reconstrucción de la forma urbana de la Cartago fenicia.

  5. Démarches novatrices en ce qui a trait à la délégation des tâches en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Journal supplement features 10 years of West African health systems research. In the wake of the devastating Ebola virus outbreak in 2014, increased attention has been paid to West Africa's poorly functioning health systems. View moreJournal supplement features 10 years of West African health systems research.

  6. ¿Quiénes son los hogares que ahorran en las instituciones financieras de Nicaragua? Un análisis empírico

    OpenAIRE

    Isabel Dauner

    2002-01-01

    En Nicaragua, solamente el 5. I % de los hogares tienen una cuenta de ahorro en un banco u otra institución. Solamente 0.90/0 de los hogares "pobres" tienen una cuenta de ahorro, contra el 8.5% de los hogares "no pobres". ¿A qué se debe este bajo nivel de ahorro institucional? El presente estudio trata de responder parcialmente a esta pregunta y dar algunas pautas de cómo seguir investigando el tema. El análisis se basa en la encuesta de medición de nivel de vida (EMNV98) realizada en Nicarag...

  7. ¿Quiénes son los hogares que ahorran en las instituciones financieras de Nicaragua? Un análisis empírico

    Directory of Open Access Journals (Sweden)

    Isabel Dauner

    2002-02-01

    Full Text Available En Nicaragua, solamente el 5. I % de los hogares tienen una cuenta de ahorro en un banco u otra institución. Solamente 0.90/0 de los hogares "pobres" tienen una cuenta de ahorro, contra el 8.5% de los hogares "no pobres". ¿A qué se debe este bajo nivel de ahorro institucional? El presente estudio trata de responder parcialmente a esta pregunta y dar algunas pautas de cómo seguir investigando el tema. El análisis se basa en la encuesta de medición de nivel de vida (EMNV98 realizada en Nicaragua en 1998. Este artículo presenta las variables utilizadas en el modelo, plantea las hipótesis en cuanto al efecto de estas variables en la probabilidad que tiene un hogar de ser dueño de una o más cuentas de ahorro, y analiza los resultados del estudio buscando el vínculo entre ahorro y crédito institucional.

  8. ¿Quién lo hizo? Datos sobre la investigación de delitos de sangre en al-Andalus

    Directory of Open Access Journals (Sweden)

    Marín, Manuela

    2005-12-01

    Full Text Available Two procedures of criminal investigation in al-Andalus are presented in this paper. First, the tadmiya, an accusation made by a seriously injured person against his or her assailant; secondly, the qasāma, an oath pronounced 50 times by the male relatives of a victim of murder accusing somebody of the crime. These two procedures are examined through several cases, historically documented, of their actual practice in al-Andalus. Jurists' opinions were not always unanimous on these issues, owing to differences in school affiliations (Mālikites against Shāfi'ites and to divergences inside the same school. Personal attitudes and social and economic relationships also played an important role in criminal investigations, as attested in the cases under study.

    En este artículo se estudian dos aspectos de la investigación sobre delitos de sangre en al-Andalus. En primer lugar, la tadmiya, inculpación hecha por una persona gravemente herida contra su atacante. En segundo lugar, la qasāma, el juramento cincuentenario que podían hacer los parientes masculinos de la víctima de un crimen contra alguien a quien acusaban de haberlo cometido. Estos dos procedimientos se examinan a través de varios casos, documentados históricamente, en que se pusieron en práctica. Las opiniones de los juristas no siempre fueron unánimes a este respecto, bien por diferencias entre las escuelas legales (mālikíes y šāfi'íes, bien por divergencias dentro de la propia escuela mālikí. Tal como puede observarse en los casos estudiados, las actitudes personales, así como las relaciones sociales y económicas, representaron un papel importante en las investigaciones sobre los delitos de sangre.

  9. INFLUENCE DES TEMPERATURES OPERATIONNELLES SUR LA PERFORMANCE D’UN REFRIGERATEUR SOLAIRE A ADSORPTION QUI FONCTIONNE AVEC LE COUPLE CHARBON ACTIF-METHANOL

    Directory of Open Access Journals (Sweden)

    H SOUALMI

    2014-12-01

    Full Text Available Le séchage des produits alimentaires au soleil est un moyen efficace, facile et économique pour conserver les aliments, en particulier les fruits. Le séchoir solaire est l'équipement le plus populaire pour le séchage des fruits. En raison de la nature intermittente de l'énergie solaire, le stockage de l'énergie thermique est nécessaire pour assurer un fonctionnement prolongé du séchoir. L'objectif principal de cette étude est d'évaluer l'efficacité du séchoir solaire intégré avec un lit en gravier comme stockage thermique. L’air dans ce séchoir est sucé naturellement grâce à la cheminé solaire le séchage. Le cabinet de séchage est envisagé théoriquement (CFD.La distribution de la vitesse et de la température de l'air à travers le séchoir solaire ont été présentés durant une journée d’Août et sous les conditions climatiques de Tlemcen (Algérie. L’effet de la présence d'un stockage thermique sur la distribution de la vitesse et de la température du flux d'air et de la température des figues ont été analysés. Les résultats montrent que la conception du séchoir solaire, comportant un stockage thermique augmente les capacités et le rendement du séchoir solaire, par l’augmentation du temps de séchage.

  10. Cultural Resources Investigations of the Upper Minnesota River (639) Project, Deuel and Grant Counties, South Dakota, and Lac Qui Parle and Yellow Medicine Counties, Minnesota,

    Science.gov (United States)

    1984-09-01

    Riparia riparia Bank Swallow Megaceryle alcyon Belted Kingfisher Bartramia longicauda Upland Sandpiper -32- Name Common Name * Charadrius vociferus...Smooth sumac Toxicodendron radicans Poison ivy Acer negundo Box elder Parthenocissus vitacea Woodbine Vitis riparia Riverbank grape Tilia americana...within the Prairie-Lakes region are generally located in close proximity to a variety of environmental zones (e.g., upland prairie, slope forest

  11. La educación en tiempos de globalización: ¿quién se beneficia? Education in the era of globalisation: who benefits?

    Directory of Open Access Journals (Sweden)

    Xavier Bonal

    2009-10-01

    Full Text Available Las políticas educativas desarrolladas en el contexto del auge del neoliberalismo económico asumen una serie de efectos beneficiosos para el crecimiento económico y la igualdad de oportunidades educativas. Su hegemonía a lo largo de los últimos años, con un especial protagonismo del Banco Mundial, se ha traducido en su extensión en diversas partes del globo, y especialmente en los países en vías de desarrollo. Dichas políticas se presentan como respuesta a los retos de la globalización y como estrategia eficaz para asegurar beneficios colectivos del desarrollo educativo, especialmente para aquellos grupos socialmente más desfavorecidos. El artículo identifica las principales tesis de la política educativa neoliberal en el terreno de las relaciones entre educación y empleo, entre expansión educativa y gasto público y en las estrategias educativas de lucha contra la pobreza. Para cada una de ellas cuestiona los efectos esperados de las propuestas políticas hegemónicas y ofrece evidencias de resultados que muestran que en ningún caso los beneficiarios son los colectivos más desfavorecidos.In the context of economic neoliberalism, educational policies assume positive effects for both economic growth and equality of educational opportunities. In recent years, this thinking has been hegemonic: it has been extended around the world and especially in developing countries (with a special role of the World Bank. Those policies are presented as a response to the challenges of globalisation and as the correct strategy to ensure collective benefits of educational development, especially for socially disadvantaged groups. This paper identifies the main theses of neoliberal educational policy. The relationship of education and labor market, the connection between educational expansion and public expenditure and educational strategies to combat poverty are explored as some of the fields where neoliberal educational policies are produced. Expected effects of educational policy measures are questioned for each of these fields. At the same time, the text provides evidence of results that show that the most disadvantaged groups are not those that can really obtain the main benefits of mainstream educational policies.

  12. Ingredients facilitating social and environmental acceptability of projects; Les ingredients qui favorisent l'acceptabilite environnementale et sociale des projets

    Energy Technology Data Exchange (ETDEWEB)

    Bourke, P. [Regroupement des conseils regionaux de l' environnement, PQ (Canada)

    2010-07-01

    This presentation discussed the essential factors that must be considered to obtain social acceptance of wind power projects. It addressed issues such as public perception of projects, public concerns and various levels of conflict that may arise that can jeopardize the project development. The importance of transparency and constructive dialogue among all stakeholders was emphasized. A graph was included to show the level of receptiveness by the public towards different energy projects, notably solar (80 percent), wind (75 percent), natural gas pipelines (38 percent) and nuclear energy (11 percent). The presentation emphasized that Quebecers understand the need for developing new sources of energy, and 95 percent believe that a substitute should be found for oil imports. figs.

  13. 'No me digas nada: yo te diré quién eres': El engranaje de la estereotipa y el horror ocampianos

    Directory of Open Access Journals (Sweden)

    Mónica Zapata

    2003-11-01

    de sus versiones (chiste, parodia, sátira el rasgo de humor conjura el efecto perturbador que produce la aparición súbita del motivo de horror. El estereotipo, componente esencial de la sátira ocampiana, juega con la ambigüedad, tanto a nivel de los personajes como para el alcance pragmático de los relatos. Potencialmente peligroso y despreciable, el estereotipo es fuente de cohesión social: cuando, privados de conocimientos empíricos, nos remitimos a fuentes de segunda mano y asimilamos imágenes de manera indiscriminada porque “así lo quiere la tradición”, apelamos al estereotipo, que nos conforta en la sensación de pertenecer a un cuerpo social solidario... y nos aleja del cuerpo. A nivel de los textos ocampianos, para que el estereotipo sea eficaz y logre hacer reír a pesar de la presencia obvia del horror (cuerpos deformes, crímenes, violaciones... debe poder ser reconocido por un público advertido. Sin embargo, el vértigo que produce la oscilación entre lo familiar y lo que “no soy yo” alcanzará probablemente también a un lector extranjero

  14. ¿Quién hizo qué?: diferencias entre adultos jóvenes y mayores en la memoria para un atraco

    Directory of Open Access Journals (Sweden)

    Alaitz Aizpurua

    2014-01-01

    Full Text Available La probabilidad de que una persona mayor tenga que declarar como testigo o víctima de un atraco o un suceso similar aumenta en función de la esperanza de vida de la población. Por ello, resulta relevante conocer si las personas mayores producen testimonios menos exactos que los jóvenes, así como determinar cuáles son las circunstancias en las que pueden ser más proclives a cometer errores. En este estudio utilizamos una prueba de reconocimiento para analizar la memoria para las acciones de un atraco en adultos jóvenes y mayores. Aunque no hubo diferencias en los aciertos, las personas mayores cometieron una proporción superior de falsas alarmas y resultaron menos exactas que los jóvenes en el reconocimiento de las acciones del suceso. Además, las personas mayores tuvieron más dificultades que los jóvenes a la hora determinar el autor de las acciones correctamente reconocidas como pertenecientes al atraco. Por lo tanto, los déficits de las personas mayores en el control del origen de la información que recuerdan podrían ayudar a explicar la menor exactitud de su memoria para el suceso, un hallazgo especialmente relevante al tomar declaración a una persona de edad avanzada.

  15. Radiotherapy for testicular seminoma: changes over the past 10 years; Radiotherapie des seminomes testiculaires: ce qui a change ces dix dernieres annees

    Energy Technology Data Exchange (ETDEWEB)

    Mirimanoff, R.O. [Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne (Switzerland)

    2003-11-01

    The STIC 2001 and STIC 2002 projects intend to allow the implementation and the assessment of Intensity Modulated Radiation Therapy in France. IMRT is an innovative technique in which the high-dose radiation volume conforms to an accurately defined target volume with less morbidity to the surrounding normal tissues. The main medical objectives of the projects are (1) to improve the therapeutic index while decreasing acute toxicity and late sequelae (mainly xerostomia and acute mucite for head and neck tumors), which allows an increase in the radiation dose to the tumor and then a better tumor control; (2) to propose a salvage treatment to patients who locally recurred in previously irradiated sites; (3) to determine the optimal treatment guidelines for a safe use of the technique in clinical routine. Our projects also aim at comparing IMRT and 3D conformal treatments on the one hand (STIC 2001), and IMRT and conventional treatments on the other hand (STIC 2002), with regard to costs. As a matter of fact, the use of IMRT is presently limited in France because its implementation requires high investment and personnel costs. The seventeen French Regional Cancer Centres involved in the two projects intend to study the additional cost of the use IMRT in comparison with the use of standard techniques, which appears to be a step for a wide use of this technique in France. Each of the studies is two-year prospective, and includes patients with head and neck tumors treated with a curative intend (post operative or exclusive treatments for STIC 2002 and STIC 2002), and patients with a prostate cancer (STIC 2001). (author)

  16. “Dime cómo vendes y te diré quién eres”: actividades de imagen e identidad en la publicidad de Yoigo

    Directory of Open Access Journals (Sweden)

    Vizcaíno María José García

    2016-11-01

    Full Text Available Este trabajo analiza los anuncios de televisión y prensa de la compañía española de telefonía móvil Yoigo para explorar cómo la publicidad usa la apelación emocional para persuadir al consumidor a adquirir un servicio. El marco teórico se basa, por una parte, en el concepto de efecto social del acto comunicativo (Bravo, 2008. The implications of studying politeness in Spanish-speaking contexts: a discussion. Pragmatics, 18 (4: 577–603 y el de actividad de imagen (Hernández Flores, 2013. Actividad de imagen: caracterización y tipología en la interacción comunicativa. Pragmática Sociocultural, 1(2: 175–198, entendiendo la imagen social desde las categorías básicas de autonomía y afiliación (Bravo, 1999. ¿Imagen “positiva” vs. imagen “negativa”?: Pragmática sociocultural y componentes de face. Oralia, 2: 155–184 con sus manifestaciones grupal e individual (Bravo, 1999; 2002. Actos asertivos y cortesía: Imagen del rol en el discurso de académicos argentinos. En D. Bravo y M. E. Placencia (Eds., Actos de habla y cortesía en el español (pp. 141–174. Munich: Lincom Europa. Por otro lado, se parte de las propuestas de identidad de Spencer-Oatey (2007, 2010. Theories of identity and the analysis of face. Journal of Pragmatics, 39, 639–656; Face, identity and interactional goals. En F. Bargiela-Chiappini y M. Haugh (eds., Face, Communication and Social Interaction (pp. 137–154 y los tipos de valores centrales e individuales de los que se nutren tanto la imagen social como la identidad (Schwartz y Bardi, 2001. Value hierarquies across cultures. Take a similarities perspective. Journal of Cross-Cultural Psychology, 32(3, 268-290. Los resultados de los análisis demuestran que en los anuncios de Yoigo los valores de honestidad y originalidad están presentes en las estrategias comunicativas elegidas, lo que supone una serie de actividades de imagen (del tipo de autoimagen, cortesía y descortesía donde la afiliación y la autonomía – tanto de grupo como individual – se ponen de manifiesto. Así, las estrategias realizadas por los anuncios utilizan atributos conocidos de la identidad del consumidor español y de su imagen social para lograr su propósito persuasivo: convencerle para contratar el servicio ofrecido.

  17. Una cançó de refrany i cobles glossadores del segle XVI basada en la frase "Mal aja qui en dones fia"

    Directory of Open Access Journals (Sweden)

    Josep Romeu i Figueras

    2015-11-01

    Full Text Available In this paper the author studies the origin, spread and connotations of a misogyny proverb picked up from a xvi century refrain that circulated in Valencia and Catalonia as a symbiosis of popular tradition and Renaissance flavour.

  18. Paradisus corporalis est quies claustralis: usos e sentidos do claustro beneditino no Ocidente medieval - doi: 10.4025/actascieduc.v33i1.12491

    Directory of Open Access Journals (Sweden)

    Maria Cristina Correia Leandro Pereira

    2011-07-01

    Full Text Available O claustro de um mosteiro beneditino é um de seus lugares mais privilegiados e característicos. No entanto, a palavra que designa este território, por excelência, dos monges não teve sempre o mesmo significado, assim como aquele espaço não conheceu sempre as mesmas utilizações. É nosso objetivo estudarmos aqui o claustro no contexto do Ocidente medieval, atentando para a gênese do termo e as relações deste espaço com o lugar por ele ocupado no imaginário religioso da época e no quotidiano dos monges beneditinos

  19. Fukushima, an accident which will leave a deep mark in the nuclear industry; Fukushima, un accident qui laissera une marque profonde sur le nucleaire civil

    Energy Technology Data Exchange (ETDEWEB)

    Vallee, Alain [International Nuclear Academy, 1, avenue de Verdun, BP 60190, 71105 Chalon-sur-Saone Cedex (France)

    2011-07-01

    Fukushima is the third major accident in the short history of civilian nuclear reactors. As the two previous ones, Three Mile Island and Chernobyl, it has delivered lessons which have to be learnt by governments, nuclear organizations and industry. Among them, the most important ones are the followings: - The past upgrades of the operating reactors against severe accidents has to be reassessed; - The requirements on the plant to sustain external hazards (earthquakes, flooding,...) has to be reviewed and improved in some cases; - Plants have to be tested against unrealistic situations to verify that no cliff edge effect can be expected; - The competence and the independence of the Safety Bodies have to be verified. The situation in the Fukushima reactors is not yet completely stabilized and it will take years before a return to normal life in the vicinity can take place; nevertheless, considering the size of the disaster, due to the exceptional magnitude of the earthquake and the height of the tsunami, the consequences of the nuclear part of the event are rather low: no casualty and limited risks of cancer for people in the future. (author)

  20. ¿Quién imagina la independencia? A propósito de la celebración del bicentenario en Colombia

    Directory of Open Access Journals (Sweden)

    Eduardo Restrepo

    2010-10-01

    Full Text Available El artículo se pregunta por tres aspectos relacionados con las políticas de la ignorancia y los silenciamientos que operan en las retóricas y agendas celebracionistas del Bicentenario de la Independencia en Colombia. El primer aspecto subraya que la colonialidad no terminó en el siglo XIX, sino que se mantiene fuertemente hasta hoy. El segundo, que se hace indispensable una deselitización de las genealogías de la colombianidad, incluyendo lo que aparece como Independencia. Finalmente se comprende cómo este tipo de eventos responden más a las preocupaciones e historicidad de quienes celebran, que a aquello supuestamente celebrado.