Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models

Science.gov (United States)

Nguyen, Liem H.; Robinton, Daisy A.; Seligson, Marc; Wu, Linwei; Li, Lin; Rakheja, Dinesh; Comerford, Sarah; Ramezani, Saleh; Sun, Xiankai; Parikh, Monisha; Yang, Erin; Powers, John T.; Shinoda, Gen; Shah, Samar; Hammer, Robert; Daley, George Q.; Zhu, Hao

2014-01-01

SUMMARY Lin28a/b are RNA-binding proteins that influence stem cell maintenance, metabolism, and oncogenesis. Poorly differentiated, aggressive cancers often overexpress Lin28, but its role in tumor initiation or maintenance has not been definitively addressed. We report that LIN28B overexpression is sufficient to initiate hepatoblastoma and hepatocellular carcinoma in murine models. We also detected Lin28b overexpression in MYC-driven hepatoblastomas, and liver-specific deletion of Lin28a/b reduced tumor burden, extended latency, and prolonged survival. Both intravenous siRNA against Lin28b and conditional Lin28b deletion reduced tumor burden and prolonged survival. Igf2bp proteins are upregulated and Igf2bp3 is required in the context of LIN28B overexpression to promote growth. Thus, multiple murine models demonstrate that Lin28b is both sufficient to initiate liver cancer and necessary for its maintenance. PMID:25117712

Kinetic and sequence-structure-function analysis of known LinA variants with different hexachlorocyclohexane isomers.

Directory of Open Access Journals (Sweden)

Pooja Sharma

Full Text Available BACKGROUND: Here we report specific activities of all seven naturally occurring LinA variants towards three different isomers, α, γ and δ, of a priority persistent pollutant, hexachlorocyclohexane (HCH. Sequence-structure-function differences contributing to the differences in their stereospecificity for α-, γ-, and δ-HCH and enantiospecificity for (+- and (--α -HCH are also discussed. METHODOLOGY/PRINCIPAL FINDINGS: Enzyme kinetic studies were performed with purified LinA variants. Models of LinA2(B90A A110T, A111C, A110T/A111C and LinA1(B90A were constructed using the FoldX computer algorithm. Turnover rates (min(-1 showed that the LinAs exhibited differential substrate affinity amongst the four HCH isomers tested. α-HCH was found to be the most preferred substrate by all LinA's, followed by the γ and then δ isomer. CONCLUSIONS/SIGNIFICANCE: The kinetic observations suggest that LinA-γ1-7 is the best variant for developing an enzyme-based bioremediation technology for HCH. The majority of the sequence variation in the various linA genes that have been isolated is not neutral, but alters the enantio- and stereoselectivity of the encoded proteins.

Lin4Neuro: a customized Linux distribution ready for neuroimaging analysis.

Science.gov (United States)

Nemoto, Kiyotaka; Dan, Ippeita; Rorden, Christopher; Ohnishi, Takashi; Tsuzuki, Daisuke; Okamoto, Masako; Yamashita, Fumio; Asada, Takashi

2011-01-25

A variety of neuroimaging software packages have been released from various laboratories worldwide, and many researchers use these packages in combination. Though most of these software packages are freely available, some people find them difficult to install and configure because they are mostly based on UNIX-like operating systems. We developed a live USB-bootable Linux package named "Lin4Neuro." This system includes popular neuroimaging analysis tools. The user interface is customized so that even Windows users can use it intuitively. The boot time of this system was only around 40 seconds. We performed a benchmark test of inhomogeneity correction on 10 subjects of three-dimensional T1-weighted MRI scans. The processing speed of USB-booted Lin4Neuro was as fast as that of the package installed on the hard disk drive. We also installed Lin4Neuro on a virtualization software package that emulates the Linux environment on a Windows-based operation system. Although the processing speed was slower than that under other conditions, it remained comparable. With Lin4Neuro in one's hand, one can access neuroimaging software packages easily, and immediately focus on analyzing data. Lin4Neuro can be a good primer for beginners of neuroimaging analysis or students who are interested in neuroimaging analysis. It also provides a practical means of sharing analysis environments across sites.

Lin28 Mediates Cancer Chemotherapy Resistance via Regulation of miRNA Signaling.

Science.gov (United States)

Xu, Chaoyang; Xie, Shuduo; Song, Chunjiao; Huang, Liming; Jiang, Zhinong

2014-06-01

Chemotherapy resistance is one of the major obstacles limiting the success of cancer drug treatment. Among the mechanisms of resistance to chemotherapy treatment, there are those closely related to P-Glycoprotein, multidrug resistance-related protein, glutathione S-transferase pi and topoisomerase-II. Lin28 is a highly conserved RNA-binding protein, it consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs. In previous preclinical and clinical studies, positive Lin28 expression in cancer cells was correlated with decreased sensitivity to chemotherapy. And Lin28 could mediate cancer chemotherapy resistance via regulation of miR107 and Let-7 MiRNA. This article reviews current knowledge on predictive value of Lin28 in response to chemotherapy. Better understanding of its role may facilitate patient's selection of therapeutic regimen and lead to optimal clinical outcome.

Lin28b stimulates the reprogramming of rat Müller glia to retinal progenitors

Energy Technology Data Exchange (ETDEWEB)

Zhao, Chen; Tao, Zui; Xue, Langyue; Zeng, Yuxiao [Southwest Hospital/Southwest Eye Hospital, Third Military Medical University, Chongqing 400038 (China); Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing 400038 (China); Wang, Yi, E-mail: wangyieye@aliyun.com [Southwest Hospital/Southwest Eye Hospital, Third Military Medical University, Chongqing 400038 (China); Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing 400038 (China); Xu, Haiwei, E-mail: haiweixu2001@163.com [Southwest Hospital/Southwest Eye Hospital, Third Military Medical University, Chongqing 400038 (China); Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing 400038 (China); Yin, Zheng Qin, E-mail: qinzyin@aliyun.com [Southwest Hospital/Southwest Eye Hospital, Third Military Medical University, Chongqing 400038 (China); Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing 400038 (China)

2017-03-01

In lower-order vertebrates, Müller glia exhibit characteristics of retinal progenitor cells, while in higher vertebrates, such as mammals, the regenerative capacity of Müller glia is limited. Recently, we reported that Lin28b promoted the trans-differentiation of Müller cells to rod photoreceptor and bipolar cells in the retina of retinitis pigmentosa rat model, whereas it is unclear whether Lin28b can stimulate the reprogramming of Müller glia in vitro for transplantation into a damaged retina. In the present study, Long-Evens rat Müller glia were infected with Adeno-Lin28b or Adeno-GFP. Over-expression of Lin28b in isolated rat Müller glia resulted in the suppression of GFAP expression, enhancement of cell proliferation and a significant increase of the expression of retinal progenitor markers 5 days after infection. Moreover, Lin28b caused a significant reduction of the Let-7 family of microRNAs. Following sub-retinal space transplantation, Müller glia-derived retinal progenitors improved b-wave amplification of 30d Royal College of Surgeons retinitis pigmentosa model (RCS-P+) rats, as detected by electroretinography (ERG) recordings. Taken together, these data suggest that the up-regulation of Lin28b expression facilitated the reprogramming of Müller cells toward characteristics of retinal progenitors. - Highlights: • Lin28b reprograms Müller glia to retinal progenitors. • Let-7 micrRNAs are suppressed by Lin28b. • Transplantation of reprogrammed Müller glia restores retinal function.

Lin28b stimulates the reprogramming of rat Müller glia to retinal progenitors

International Nuclear Information System (INIS)

Zhao, Chen; Tao, Zui; Xue, Langyue; Zeng, Yuxiao; Wang, Yi; Xu, Haiwei; Yin, Zheng Qin

2017-01-01

In lower-order vertebrates, Müller glia exhibit characteristics of retinal progenitor cells, while in higher vertebrates, such as mammals, the regenerative capacity of Müller glia is limited. Recently, we reported that Lin28b promoted the trans-differentiation of Müller cells to rod photoreceptor and bipolar cells in the retina of retinitis pigmentosa rat model, whereas it is unclear whether Lin28b can stimulate the reprogramming of Müller glia in vitro for transplantation into a damaged retina. In the present study, Long-Evens rat Müller glia were infected with Adeno-Lin28b or Adeno-GFP. Over-expression of Lin28b in isolated rat Müller glia resulted in the suppression of GFAP expression, enhancement of cell proliferation and a significant increase of the expression of retinal progenitor markers 5 days after infection. Moreover, Lin28b caused a significant reduction of the Let-7 family of microRNAs. Following sub-retinal space transplantation, Müller glia-derived retinal progenitors improved b-wave amplification of 30d Royal College of Surgeons retinitis pigmentosa model (RCS-P+) rats, as detected by electroretinography (ERG) recordings. Taken together, these data suggest that the up-regulation of Lin28b expression facilitated the reprogramming of Müller cells toward characteristics of retinal progenitors. - Highlights: • Lin28b reprograms Müller glia to retinal progenitors. • Let-7 micrRNAs are suppressed by Lin28b. • Transplantation of reprogrammed Müller glia restores retinal function.

Importance of the pluripotency factor LIN28 in the mammalian nucleolus during early embryonic development.

Science.gov (United States)

Vogt, Edgar J; Meglicki, Maciej; Hartung, Kristina Ilka; Borsuk, Ewa; Behr, Rüdiger

2012-12-01

The maternal nucleolus is required for proper activation of the embryonic genome (EGA) and early embryonic development. Nucleologenesis is characterized by the transformation of a nucleolar precursor body (NPB) to a mature nucleolus during preimplantation development. However, the function of NPBs and the involved molecular factors are unknown. We uncover a novel role for the pluripotency factor LIN28, the biological significance of which was previously demonstrated in the reprogramming of human somatic cells to induced pluripotent stem (iPS) cells. Here, we show that LIN28 accumulates at the NPB and the mature nucleolus in mouse preimplantation embryos and embryonic stem cells (ESCs), where it colocalizes with the nucleolar marker B23 (nucleophosmin 1). LIN28 has nucleolar localization in non-human primate (NHP) preimplantation embryos, but is cytoplasmic in NHP ESCs. Lin28 transcripts show a striking decline before mouse EGA, whereas LIN28 protein localizes to NPBs at the time of EGA. Following knockdown with a Lin28 morpholino, the majority of embryos arrest between the 2- and 4-cell stages and never develop to morula or blastocyst. Lin28 morpholino-injected embryos arrested at the 2-cell stage were not enriched with nucleophosmin at presumptive NPB sites, indicating that functional NPBs were not assembled. Based on these results, we propose that LIN28 is an essential factor of nucleologenesis during early embryonic development.

LIN28 phosphorylation by MAPK/ERK couples signaling to the post-transcriptional control of pluripotency

Science.gov (United States)

Tsanov, Kaloyan M.; Pearson, Daniel S.; Wu, Zhaoting; Han, Areum; Triboulet, Robinson; Seligson, Marc T.; Powers, John T.; Osborne, Jihan K.; Kane, Susan; Gygi, Steven P.; Gregory, Richard I.; Daley, George Q.

2016-01-01

Signaling and post-transcriptional gene control are both critical for the regulation of pluripotency1,2, yet how they are integrated to influence cell identity remains poorly understood. LIN28 (also known as LIN28A), a highly conserved RNA-binding protein (RBP), has emerged as a central post-transcriptional regulator of cell fate through blockade of let-7 microRNA (miRNA) biogenesis and direct modulation of mRNA translation3. Here we show that LIN28 is phosphorylated by MAPK/ERK in pluripotent stem cells (PSCs), which increases its levels via post-translational stabilization. LIN28 phosphorylation had little impact on let-7 but enhanced LIN28’s effect on its direct mRNA targets, revealing a mechanism that uncouples LIN28’s let-7-dependent and independent activities. We have linked this mechanism to the induction of pluripotency by somatic cell reprogramming and the transition from naïve to primed pluripotency. Collectively, our findings indicate that MAPK/ERK directly impacts LIN28, defining an axis that connects signaling, post-transcriptional gene control, and cell fate regulation. PMID:27992407

A Dynamic Attitude Measurement System Based on LINS

Directory of Open Access Journals (Sweden)

Hanzhou Li

2014-08-01

Full Text Available A dynamic attitude measurement system (DAMS is developed based on a laser inertial navigation system (LINS. Three factors of the dynamic attitude measurement error using LINS are analyzed: dynamic error, time synchronization and phase lag. An optimal coning errors compensation algorithm is used to reduce coning errors, and two-axis wobbling verification experiments are presented in the paper. The tests indicate that the attitude accuracy is improved 2-fold by the algorithm. In order to decrease coning errors further, the attitude updating frequency is improved from 200 Hz to 2000 Hz. At the same time, a novel finite impulse response (FIR filter with three notches is designed to filter the dither frequency of the ring laser gyro (RLG. The comparison tests suggest that the new filter is five times more effective than the old one. The paper indicates that phase-frequency characteristics of FIR filter and first-order holder of navigation computer constitute the main sources of phase lag in LINS. A formula to calculate the LINS attitude phase lag is introduced in the paper. The expressions of dynamic attitude errors induced by phase lag are derived. The paper proposes a novel synchronization mechanism that is able to simultaneously solve the problems of dynamic test synchronization and phase compensation. A single-axis turntable and a laser interferometer are applied to verify the synchronization mechanism. The experiments results show that the theoretically calculated values of phase lag and attitude error induced by phase lag can both match perfectly with testing data. The block diagram of DAMS and physical photos are presented in the paper. The final experiments demonstrate that the real-time attitude measurement accuracy of DAMS can reach up to 20″ (1σ and the synchronization error is less than 0.2 ms on the condition of three axes wobbling for 10 min.

A Dynamic Attitude Measurement System Based on LINS

Science.gov (United States)

Li, Hanzhou; Pan, Quan; Wang, Xiaoxu; Zhang, Juanni; Li, Jiang; Jiang, Xiangjun

2014-01-01

A dynamic attitude measurement system (DAMS) is developed based on a laser inertial navigation system (LINS). Three factors of the dynamic attitude measurement error using LINS are analyzed: dynamic error, time synchronization and phase lag. An optimal coning errors compensation algorithm is used to reduce coning errors, and two-axis wobbling verification experiments are presented in the paper. The tests indicate that the attitude accuracy is improved 2-fold by the algorithm. In order to decrease coning errors further, the attitude updating frequency is improved from 200 Hz to 2000 Hz. At the same time, a novel finite impulse response (FIR) filter with three notches is designed to filter the dither frequency of the ring laser gyro (RLG). The comparison tests suggest that the new filter is five times more effective than the old one. The paper indicates that phase-frequency characteristics of FIR filter and first-order holder of navigation computer constitute the main sources of phase lag in LINS. A formula to calculate the LINS attitude phase lag is introduced in the paper. The expressions of dynamic attitude errors induced by phase lag are derived. The paper proposes a novel synchronization mechanism that is able to simultaneously solve the problems of dynamic test synchronization and phase compensation. A single-axis turntable and a laser interferometer are applied to verify the synchronization mechanism. The experiments results show that the theoretically calculated values of phase lag and attitude error induced by phase lag can both match perfectly with testing data. The block diagram of DAMS and physical photos are presented in the paper. The final experiments demonstrate that the real-time attitude measurement accuracy of DAMS can reach up to 20″ (1σ) and the synchronization error is less than 0.2 ms on the condition of three axes wobbling for 10 min. PMID:25177802

Le nævus épidermique verruqueux inflammatoire linéaire ...

African Journals Online (AJOL)

Le nævus épidermique verruqueux inflammatoire linéaire (NEVIL) est une affection rare correspondant à des hyperplasies épidermiques bénignes qui se présentent cliniquement sous forme de lésions linéaires unilatérales hyperkératosiques. Une adolescente âgée de 16 ans, sans antécédents, présentait depuis la ...

107 Définition structurale des linéaments par traitement d'image ...

African Journals Online (AJOL)

Valued Packard Bell Customer

The Ngovayang massif represents a key domain in understanding the geodynamics of the northern border of the Congo craton in South Cameroon. Remote sensing works .... linéaments liés au socle rocheux et aux accidents tectoniques (Minyem, 1994 [2]). Ces linéaments sont repartis selon trois directions. - la direction ...

Address of U.S. President George W. Bush / George W. Bush

Index Scriptorium Estoniae

Bush, George W., 1946-

2005-01-01

Ilmunud ka: Eesti Päevaleht : Mõte 10. juuni lk. 9-11. Ameerika Ühendriikide presidendi George Bushi Läti visiidi ajal 7. mail peetud kõne. Ajal. Eesti Päevaleht : Möte toodud ka George W. Bushi CV. Ajal. The Baltic Times lüh.

LIN-32/Atonal Controls Oxygen Sensing Neuron Development in Caenorhabditis elegans

DEFF Research Database (Denmark)

Romanos, Teresa Rojo; Pladevall-Morera, David; Langebeck-Jensen, Kasper

2017-01-01

HLH) family of transcription factors has multiple functions in neurogenesis. Here, we identified the LIN-32/Atonal bHLH transcription factor as a key regulator of URXL/R oxygen-sensing neuron development in Caenorhabditis elegans. When LIN-32/Atonal expression is lost, the expression of URX specification......Development of complex nervous systems requires precisely controlled neurogenesis. The generation and specification of neurons occur through the transcriptional and post-Transcriptional control of complex regulatory networks. In vertebrates and invertebrates, the proneural basic-helix-loop-helix (b...... and terminal differentiation genes is abrogated. As such, lin-32 mutant animals are unable to respond to increases in environmental oxygen. The URX neurons are generated from a branch of the cell lineage that also produces the CEPDL/R and URADL/R neurons. We found development of these neurons is also defective...

Sajan D George

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. Sajan D George. Articles written in Resonance – Journal of Science Education. Volume 17 Issue 7 July 2012 pp 682-690 General Article. Microfluidics – A Lab in Your Palm · Dileep Mampallil Sajan D George · More Details Fulltext PDF ...

Regulation of C. elegans L4 cuticle collagen genes by the heterochronic protein LIN-29.

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Abete-Luzi, Patricia; Eisenmann, David M

2018-05-01

The cuticle, the outer covering of the nematode C. elegans, is synthesized five times during the worm's life by the underlying hypodermis. Cuticle collagens, the major cuticle component, are encoded by a large family of col genes and, interestingly, many of these genes express predominantly at a single developmental stage. This temporal preference motivated us to investigate the mechanisms underlying col gene expression and here we focus on a subset of col genes expressed in the L4 stage. We identified minimal promoter regions of <300 bp for col-38, col-49, and col-63. In these regions, we predicted cis-regulatory sequences and evaluated their function in vivo via mutagenesis of a col-38p::yfp reporter. We used RNAi to study the requirement for candidate transcription regulators ELT-1 and ELT-3, LIN-29, and the LIN-29 co-factor MAB-10, and found LIN-29 to be necessary for the expression of four L4-specific genes (col-38, col-49, col-63, and col-138). Temporal misexpression of LIN-29 was also sufficient to activate these genes at a different developmental stage. The LIN-29 DNA-binding domain bound the col-38, col-49, and col-63 minimal promoters in vitro. For col-38 we showed that the LIN-29 sites necessary for reporter expression in vivo are also bound in vitro: this is the first identification of specific binding sites for LIN-29 necessary for in vivo target gene expression. © 2018 Wiley Periodicals, Inc.

Clinical application of Lin's biopsy grasper for intrauterine targeted biopsy and polypectomy during office hysteroscopy.

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Cheng, Hsin-Yi; Lin, Bao-Liang; Tseng, Jen-Yu; Ueno, Kazunori; Nakada, Sakura

2018-06-01

Hysteroscopy has widely been used for diagnosis of the uterine cavity; however, target biopsy has often been difficult in part to the inherent limitations of ancillary instruments. Lin's biopsy grasper was specifically designed to work in conjunction with a flexible hysteroscope to obtain intrauterine biopsy under transabdominal sonography. Herein, we share our clinical experience in the management of endometrial abnormalities with the use of Lin's biopsy grasper during office-based hysteroscopy. From February 2006 to November 2016, the use of Lin's biopsy grasper for tissue biopsy was attempted on 126 cases. We retrospectively recorded and analyzed the patients' preoperative characteristics and biopsy outcomes to demonstrate the feasibility and efficacy of Lin's biopsy grasper. Out of the one hundred and twenty-six enrolled patients, satisfactory targeted biopsies were achieved; including high diagnostic rate (92.1%, with 116 cases confirmed histologically) and adequate tissue retrieval (77.8%, with 98 cases obtaining optimal specimen volume). All patients tolerated the procedure without analgesics or anesthesia. Diagnostic flexible hysteroscopy combined with the use of Lin's biopsy grasper has proven to be an effective tool for intrauterine evaluation and obtaining tissue sample. Copyright © 2018. Published by Elsevier B.V.

régression linéaire multiple

African Journals Online (AJOL)

Mots clés: Alcools et phénols – Représentation numérique de la structure chimique – Facteur acentrique – Régression linéaire multiple – Modèle RSP hybride. English Title: Structure / acentric factor relationship of alcohols and phenols: genetic algorithm – multiple linear regression approach. English Abstract. The acentric ...

Association of Lin-28A rs3811464 Variant with Susceptibility to Type 2 Diabetes

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Mona Khodabandeh

2017-11-01

Full Text Available Introduction: It has been suggested that Lin-28A and the let-7 microRNA family (Lin-28/let-7 axis play a critical role in the control of glucose metabolism, insulin sensitivity and resistance to diabetes. Aim: This case-control study aimed at evaluating the association between Lin-28 rs3811464 polymorphism and the susceptibility to Type 2 Diabetes (T2D in a sample of Iranian population. Materials and Methods: This study involved 172 T2D patients and 160 non-diabetic age and gender-matched controls. Lin 28A rs3811464 genotypes were determined by Polymerase Chain Reaction–Restriction Fragment Length Polymorphism (PCR-RFLP technique. Results: The results showed that the frequency of the AA genotype was significantly higher in control subjects than in diabetic patients (13.12% vs. 4.65%. In addition, binary logistic regression analysis revealed that rs3811464-AA genotype was significantly associated to T2D after adjustment for BMI, age and lipid profiles. Indeed, subjects with AA genotype were less likely to develop T2D than GG and AG subjects (OR of 0.26, 95% CI 0.10-0.66, p=0.005. Conclusion: The findings of our study suggest that the Lin 28A rs3811464 is associated with type 2 diabetes susceptibility and subjects with AA genotypes were less likely to develop T2D diabetes.

Metabolomics of hexachlorocyclohexane (HCH) transformation: ratio of LinA to LinB determines metabolic fate of HCH isomers.

Science.gov (United States)

Geueke, Birgit; Garg, Nidhi; Ghosh, Sneha; Fleischmann, Thomas; Holliger, Christof; Lal, Rup; Kohler, Hans-Peter E

2013-04-01

Although the production and use of technical hexachlorocyclohexane (HCH) and lindane (the purified insecticidal isomer γ-HCH) are prohibited in most countries, residual concentrations still constitute an immense environmental burden. Many studies describe the mineralization of γ-HCH by bacterial strains under aerobic conditions. However, the metabolic fate of the other HCH isomers is not well known. In this study, we investigated the transformation of α-, β-, γ-, δ-, ε-HCH, and a heptachlorocyclohexane isomer in the presence of varying ratios of the two enzymes that initiate γ-HCH degradation, a dehydrochlorinase (LinA) and a haloalkane dehalogenase (LinB). Each substrate yielded a unique metabolic profile that was strongly dependent on the enzyme ratio. Comparison of these results to those of in vivo experiments with different bacterial isolates showed that HCH transformation in the tested strains was highly optimized towards productive metabolism of γ-HCH and that under these conditions other HCH-isomers were metabolized to mixtures of dehydrochlorinated and hydroxylated side-products. In view of these results, bioremediation efforts need very careful planning and toxicities of accumulating metabolites need to be evaluated. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

George Hampton (1920-2004)

CERN Multimedia

2004-01-01

George Hampton, who died recently, was CERN's Director of Administration in the 1960s and an important member of the team who managed the growth of CERN as it left the construction period and became a world-class physics laboratory. George came to CERN in the 1963, when the laboratory was just starting its main research activities after the intense period of construction for the Proton Synchrotron (PS). At that time the laboratory was passing through a major budget crisis, and the new Director-general, Viki Weisskopf, was faced with a completely new structure set up by his predecessor John Adams, with 12 divisions for running the laboratory reporting directly to him, and with four Directors. With the renewal of the position of Director of Administration in 1963, Weisskopf selected George Hampton from candidates from the Member States. He came from the UK Atomic Energy Authority, but had worked earlier as a delegate to the international Civil Aviation Organization. George's position at the start was to hel...

Biodegradation of γ-hexachlorocyclohexane by transgenic hairy root cultures of Cucurbita moschata that accumulate recombinant bacterial LinA.

Science.gov (United States)

Nanasato, Yoshihiko; Namiki, Sayuri; Oshima, Masao; Moriuchi, Ryota; Konagaya, Ken-Ichi; Seike, Nobuyasu; Otani, Takashi; Nagata, Yuji; Tsuda, Masataka; Tabei, Yutaka

2016-09-01

γ-HCH was successfully degraded using LinA-expressed transgenic hairy root cultures of Cucurbita moschata . Fusing an endoplasmic reticulum-targeting signal peptide to LinA was essential for stable accumulation in the hairy roots. The pesticide γ-hexachlorocyclohexane (γ-HCH) is a persistent organic pollutant (POP) that raises public health and environmental pollution concerns worldwide. Although several isolates of γ-HCH-degrading bacteria are available, inoculating them directly into γ-HCH-contaminated soil is ineffective because of the bacterial survival rate. Cucurbita species incorporate significant amounts of POPs from soils compared with other plant species. Here, we describe a novel bioremediation strategy that combines the bacterial degradation of γ-HCH and the efficient uptake of γ-HCH by Cucurbita species. We produced transgenic hairy root cultures of Cucurbita moschata that expressed recombinant bacterial linA, isolated from the bacterium Sphingobium japonicum UT26. The LinA protein was accumulated stably in the hairy root cultures by fusing an endoplasmic reticulum (ER)-targeting signal peptide to LinA. Then, we demonstrated that the cultures degraded more than 90 % of γ-HCH (1 ppm) overnight and produced the γ-HCH metabolite 1,2,4-trichlorobenzene, indicating that LinA degraded γ-HCH. These results indicate that the gene linA has high potential for phytoremediation of environmental γ-HCH.

LINS Curve in Romanian Economy

Directory of Open Access Journals (Sweden)

Emilian Dobrescu

2016-02-01

Full Text Available The paper presents theoretical considerations and empirical evidence to test the validity of the Laffer in Narrower Sense (LINS curve as a parabola with a maximum. Attention is focused on the so-called legal-effective tax gap (letg. The econometric application is based on statistical data (1990-2013 for Romania as an emerging European economy. Three cointegrating regressions (fully modified least squares, canonical cointegrating regression and dynamic least squares and three algorithms, which are based on instrumental variables (two-stage least squares, generalized method of moments, and limited information maximum likelihood, are involved.

[Professor LIN Guohua's experience of gold implantation at acupoint for rheumatoid arthritis].

Science.gov (United States)

Li, Jingjing; Pei, Wenya

2015-12-01

Based on the pathogenesis and symptom of rheumatoid arthritis (RA), professor LIN Guohua's unique opinion and method for RA in clinical treatment are summarized and analyzed. In the opinion of Professor Lin, RA is considered as "Jinbi" and "Gubi" in TCM, which is caused by deficient root with superficial excess. Based on the symptoms of RA, attention should be focused on lung-kidney diagnosis and treatment, and gold and catgut implantation at acupoint can be mutually combined, which is aimed to provide a special and effective method for clinical treatment of RA.

A tribute to George Plafker

Science.gov (United States)

Fuis, Gary S.; Haeussler, Peter J.; Atwater, Brian F.

2015-01-01

In a long and distinguished career, George Plafker made fundamental advances in understanding of megathrust tectonics, tsunami generation, paleoseismology, crustal neotectonics, and Alaskan geology, chiefly by means of geological field observations. George discovered that giant earthquakes result from tens of meters of seismic slip on subduction megathrusts, and he did this before the theory of plate tectonics had become a paradigm. The discovery was founded on George's comprehensive mapping of land-level changes in the aftermath of the 1964 earthquake in Alaska, and on his follow-up mapping, in 1968, in the region of the 1960 earthquakes in Chile. The mapping showed paired, parallel belts of coseismic uplift largely offshore and coseismic subsidence mostly onshore – a pattern now familiar as the initial condition assumed in simulations of subduction-zone tsunamis. George recognized, moreover, that splay faulting can play a major role in tsunami generation, and he also distinguished carefully between tectonic and landslide sources for the multiple tsunamis that accounted for nearly all the fatalities associated with the 1964 Alaska earthquake. George's classic monographs on the 1964 earthquake include findings on subduction-zone paleoseismology that he soon extended to include stratigraphic evidence for cyclic vertical deformation at the Copper River Delta, as well as recurrent uplift evidenced by flights of marine terraces at Middleton Island. As a geologist of earthquakes, George also clarified the tectonics and hazards of crustal faulting in Alaska, California, and other areas worldwide. All the while, George was mapping bedrock geology in Alaska, where he contributed importantly to today's understanding of how terranes were accreted and modified. Especially important was his documentation of the origin, movement, subduction, and collision of the Yakutat terrane in southern Alaska.

George Chester Stone (1924-2013).

Science.gov (United States)

Adler, Nancy

2014-01-01

George Chester Stone was born February 21, 1924, and died on July 13, 2013. A quiet revolutionary, George was a founder of the field of health psychology. George played critical roles conceptualizing the field of health psychology, charting its bounds and potential, promulgating guidelines for training, founding the first doctoral program in health psychology, editing influential volumes defining the new field, launching the flagship journal for the field, and establishing a home for the field within APA. He was able to accomplish all this through his talent for working collaboratively. 2014 APA, all rights reserved

George's cosmic treasure hunt

CERN Document Server

Hawking, Lucy; Parsons, Gary

2009-01-01

George and Annie explore the galaxy in this cosmic adventure from Stephen Hawking and Lucy Hawking, complete with essays from Professor Hawking about the latest in space travel. George is heartbroken when he learns that his friend Annie and her father are moving to the US. Eric has a new job working for the space program, looking for signs of life in the Universe. Eric leaves George with a gift—a book called The User’s Guide to the Universe. But Annie and Eric haven’t been gone for very long when Annie believes that she is being contacted by aliens, who have a terrible warning for her. George joins her in the US to help her with her quest—and before he knows it, he, Annie, Cosmos, and Annie’s annoying cousin Emmett have been swept up in a cosmic treasure hunt, spanning the whole galaxy and beyond. Lucy Hawking's own experiences in zero-gravity flight and interviews with astronauts at Cape Kennedy and the Johnson Space Center lend the book a sense of realism and excitement that is sure to fire up ima...

Genome packaging in EL and Lin68, two giant phiKZ-like bacteriophages of P. aeruginosa

International Nuclear Information System (INIS)

Sokolova, O.S.; Shaburova, O.V.; Pechnikova, E.V.; Shaytan, A.K.; Krylov, S.V.; Kiselev, N.A.; Krylov, V.N.

2014-01-01

A unique feature of the Pseudomonas aeruginosa giant phage phiKZ is its way of genome packaging onto a spool-like protein structure, the inner body. Until recently, no similar structures have been detected in other phages. We have studied DNA packaging in P. aeruginosa phages EL and Lin68 using cryo-electron microscopy and revealed the presence of inner bodies. The shape and positioning of the inner body and the density of the DNA packaging in EL are different from those found in phiKZ and Lin68. This internal organization explains how the shorter EL genome is packed into a large EL capsid, which has the same external dimensions as the capsids of phiKZ and Lin68. The similarity in the structural organization in EL and other phiKZ-like phages indicates that EL is phylogenetically related to other phiKZ-like phages, and, despite the lack of detectable DNA homology, EL, phiKZ, and Lin68 descend from a common ancestor. - Highlights: • We performed a comparative structural study of giant P. aeruginosa phages: EL, Lin68 and phiKZ. • We revealed that the inner body is a common feature in giant phages. • The phage genome size correlates with the overall dimensions of the inner body

Genome packaging in EL and Lin68, two giant phiKZ-like bacteriophages of P. aeruginosa

Energy Technology Data Exchange (ETDEWEB)

Sokolova, O.S., E-mail: sokolova@mail.bio.msu.ru [M.V. Lomonosov Moscow State University, Moscow (Russian Federation); A.V. Shoubnikov Institute of Crystallography RAS, Moscow (Russian Federation); Shaburova, O.V. [I.I. Mechnikov Research Institute of Vaccines and Sera, RAMS, Moscow (Russian Federation); Pechnikova, E.V. [A.V. Shoubnikov Institute of Crystallography RAS, Moscow (Russian Federation); Shaytan, A.K. [M.V. Lomonosov Moscow State University, Moscow (Russian Federation); Krylov, S.V. [I.I. Mechnikov Research Institute of Vaccines and Sera, RAMS, Moscow (Russian Federation); Kiselev, N.A. [A.V. Shoubnikov Institute of Crystallography RAS, Moscow (Russian Federation); Krylov, V.N. [I.I. Mechnikov Research Institute of Vaccines and Sera, RAMS, Moscow (Russian Federation)

2014-11-15

A unique feature of the Pseudomonas aeruginosa giant phage phiKZ is its way of genome packaging onto a spool-like protein structure, the inner body. Until recently, no similar structures have been detected in other phages. We have studied DNA packaging in P. aeruginosa phages EL and Lin68 using cryo-electron microscopy and revealed the presence of inner bodies. The shape and positioning of the inner body and the density of the DNA packaging in EL are different from those found in phiKZ and Lin68. This internal organization explains how the shorter EL genome is packed into a large EL capsid, which has the same external dimensions as the capsids of phiKZ and Lin68. The similarity in the structural organization in EL and other phiKZ-like phages indicates that EL is phylogenetically related to other phiKZ-like phages, and, despite the lack of detectable DNA homology, EL, phiKZ, and Lin68 descend from a common ancestor. - Highlights: • We performed a comparative structural study of giant P. aeruginosa phages: EL, Lin68 and phiKZ. • We revealed that the inner body is a common feature in giant phages. • The phage genome size correlates with the overall dimensions of the inner body.

Identification and Characterization of Genes That Interact with Lin-12 in Caenorhabditis Elegans

OpenAIRE

Tax, F. E.; Thomas, J. H.; Ferguson, E. L.; Horvitz, H. R.

1997-01-01

We identified and characterized 14 extragenic mutations that suppressed the dominant egg-laying defect of certain lin-12 gain-of-function mutations. These suppressors defined seven genes: sup-17, lag-2, sel-4, sel-5, sel-6, sel-7 and sel-8. Mutations in six of the genes are recessive suppressors, whereas the two mutations that define the seventh gene, lag-2, are semi-dominant suppressors. These suppressor mutations were able to suppress other lin-12 gain-of-function mutations. The suppressor ...

George and the big bang

CERN Document Server

Hawking, Lucy; Parsons, Gary

2012-01-01

George has problems. He has twin baby sisters at home who demand his parents’ attention. His beloved pig Freddy has been exiled to a farm, where he’s miserable. And worst of all, his best friend, Annie, has made a new friend whom she seems to like more than George. So George jumps at the chance to help Eric with his plans to run a big experiment in Switzerland that seeks to explore the earliest moment of the universe. But there is a conspiracy afoot, and a group of evildoers is planning to sabotage the experiment. Can George repair his friendship with Annie and piece together the clues before Eric’s experiment is destroyed forever? This engaging adventure features essays by Professor Stephen Hawking and other eminent physicists about the origins of the universe and ends with a twenty-page graphic novel that explains how the Big Bang happened—in reverse!

Variational principles of fluid mechanics and electromagnetism: imposition and neglect of the Lin constraint

International Nuclear Information System (INIS)

Allen, R.R. Jr.

1987-01-01

The Lin constraint has been utilized by a number of authors who have sought to develop Eulerian variational principles in both fluid mechanics and electromagnetics (or plasmadynamics). This dissertation first reviews the work of earlier authors concerning the development of variational principles in both the Eulerian and Lagrangian nomenclatures. In the process, it is shown whether or not the Euler-Lagrange equations that result from the variational principles are equivalent to the generally accepted equations of motion. In particular, it is shown in the case of several Eulerian variational principles that imposition of the Lin constraint results in Euler-Lagrange equations equivalent to the generally accepted equations of motion, whereas neglect of the Lin constraint results in restrictive Euler-Lagrange equations. In an effort to improve the physical motivation behind introduction of the Lin constraint, a new variational constraint is developed based on teh concept of surface forces within a fluid. Additionally, it is shown that a quantity often referred to as the canonical momentum of a charged fluid is not always a constant of the motion of the fluid; and it is demonstrated that there does not exist an unconstrained Eulerian variational principle giving rise to the generally accepted equations of motion for both a perfect fluid and a cold, electromagnetic fluid

Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively.

Science.gov (United States)

Nowak, Jakub Stanislaw; Hobor, Fruzsina; Downie Ruiz Velasco, Angela; Choudhury, Nila Roy; Heikel, Gregory; Kerr, Alastair; Ramos, Andres; Michlewski, Gracjan

2017-03-01

Lin28a inhibits the biogenesis of let-7 miRNAs by triggering the polyuridylation and degradation of their precursors by terminal uridylyltransferases TUT4/7 and 3'-5' exoribonuclease Dis3l2, respectively. Previously, we showed that Lin28a also controls the production of neuro-specific miRNA-9 via a polyuridylation-independent mechanism. Here we reveal that the sequences and structural characteristics of pre-let-7 and pre-miRNA-9 are eliciting two distinct modes of binding to Lin28a. We present evidence that Dis3l2 controls miRNA-9 production. Finally, we show that the constitutive expression of untagged Lin28a during neuronal differentiation in vitro positively and negatively affects numerous other miRNAs. Our findings shed light on the role of Lin28a in differentiating cells and on the ways in which one RNA-binding protein can perform multiple roles in the regulation of RNA processing. © 2017 Nowak et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Combustion of Pure, Hydrolyzed and Methyl Ester Formed of Jatropha Curcas Lin oil

Directory of Open Access Journals (Sweden)

Muhaji Muhaji

2015-10-01

Full Text Available The density and viscosity of vegetable oil are higher than that of diesel oil. Thus its direct combustion in the diesel engine results many problems. This research was conducted to investigate the flame characteristics of combustion of jatropha curcas lin in pure, hydrolyzed and methyl ester form. The results indicated that the combustion of pure jatropha curcas lin occurs in three stages, hydrolyzed in two stages    and methyl ester in one stage. For pure jatropha curcas lin, in the first stage, unsaturated fatty acid burned for  0.265 s.  It is followed by saturated fatty acid, burned for 0.389 s in the second stage. And, in the last stage is the burned of glycerol for 0.560 s. Meanwhile for hydrolyzed one, in the first stage, unsaturated fatty acid burned for 0.736 s, followed by saturated fatty acid, burned  for 0.326 s in the second stage. And the last, for methyl ester is the burned for 0.712 s. The highest burning rate was for methyl ester which was 0.003931cc/s. The energy releasing rate of methyl ester, which was for 13,628.67 kcal/(kg.s resembled that of diesel oil the most, while the lowest rate was for pure jatropha curcas lin which was 8,200.94 kcal/(kg.s. In addition, massive explosion occurred in the fuel containing unsaturated fatty acid and glycerol

Analysis of a lin-42/period Null Allele Implicates All Three Isoforms in Regulation of Caenorhabditis elegans Molting and Developmental Timing

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Theresa L. B. Edelman

2016-12-01

Full Text Available The Caenorhabditis elegans heterochronic gene pathway regulates the relative timing of events during postembryonic development. lin-42, the worm homolog of the circadian clock gene, period, is a critical element of this pathway. lin-42 function has been defined by a set of hypomorphic alleles that cause precocious phenotypes, in which later developmental events, such as the terminal differentiation of hypodermal cells, occur too early. A subset of alleles also reveals a significant role for lin-42 in molting; larval stages are lengthened and ecdysis often fails in these mutant animals. lin-42 is a complex locus, encoding overlapping and nonoverlapping isoforms. Although existing alleles that affect subsets of isoforms have illuminated important and distinct roles for this gene in developmental timing, molting, and the decision to enter the alternative dauer state, it is essential to have a null allele to understand all of the roles of lin-42 and its individual isoforms. To remedy this problem and discover the null phenotype, we engineered an allele that deletes the entire lin-42 protein-coding region. lin-42 null mutants are homozygously viable, but have more severe phenotypes than observed in previously characterized hypomorphic alleles. We also provide additional evidence for this conclusion by using the null allele as a base for reintroducing different isoforms, showing that each isoform can provide heterochronic and molting pathway activities. Transcript levels of the nonoverlapping isoforms appear to be under coordinate temporal regulation, despite being driven by independent promoters. The lin-42 null allele will continue to be an important tool for dissecting the functions of lin-42 in molting and developmental timing.

LIN28 expression in malignant germ cell tumors down-regulates let-7 and increases oncogene levels

Science.gov (United States)

Murray, Matthew J.; Saini, Harpreet K.; Siegler, Charlotte A.; Hanning, Jennifer E.; Barker, Emily M.; van Dongen, Stijn; Ward, Dawn M.; Raby, Katie L.; Groves, Ian J.; Scarpini, Cinzia G.; Pett, Mark R.; Thornton, Claire M.; Enright, Anton J.; Nicholson, James C.; Coleman, Nicholas

2013-01-01

Despite their clinico-pathologic heterogeneity, malignant germ-cell-tumors (GCTs) share molecular abnormalities that are likely to be functionally important. In this study, we investigated the potential significance of down-regulation of the let-7 family of tumor-suppressor microRNAs in malignant-GCTs. Microarray results from pediatric and adult samples (n=45) showed that LIN28, the negative-regulator of let-7 biogenesis, was abundant in malignant-GCTs, regardless of patient age, tumor site or histologic subtype. Indeed, a strong negative-correlation existed between LIN28 and let-7 levels in specimens with matched datasets. Low let-7 levels were biologically significant, since the sequence complementary to the 2-7nt common let-7 seed ‘GAGGUA’ was enriched in the 3′untranslated regions of mRNAs up-regulated in pediatric and adult malignant-GCTs, compared with normal gonads (a mixture of germ cells and somatic cells). We identified 27 mRNA targets of let-7 that were up-regulated in malignant-GCT cells, confirming significant negative-correlations with let-7 levels. Among 16 mRNAs examined in a largely independent set of specimens by qRT-PCR, we defined negative-associations with let-7e levels for six oncogenes, including MYCN, AURKB, CCNF, RRM2, MKI67 and C12orf5 (when including normal control tissues). Importantly, LIN28 depletion in malignant-GCT cells restored let-7 levels and repressed all of these oncogenic let-7 mRNA targets, with LIN28 levels correlating with cell proliferation and MYCN levels. Conversely, ectopic expression of let-7e was sufficient to reduce proliferation and down-regulate MYCN, AURKB and LIN28, the latter via a double-negative feedback loop. We concluded that the LIN28/let-7 pathway has a critical pathobiological role in malignant-GCTs and therefore offers a promising target for therapeutic intervention. PMID:23774216

A role for Lin28 in primordial germ cell development and germ cell malignancy

Science.gov (United States)

West, Jason A.; Viswanathan, Srinivas R.; Yabuuchi, Akiko; Cunniff, Kerianne; Takeuchi, Ayumu; Park, In-Hyun; Sero, Julia E.; Zhu, Hao; Perez-Atayde, Antonio; Frazier, A. Lindsay; Surani, M. Azim; Daley, George Q.

2009-01-01

The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse embryo thwarts efforts to investigate molecular mechanisms of germ cell specification. Stella marks the minute founder population of the germ lineage1,2. Here we differentiate mouse embryonic stem cells (ESCs) carrying a Stella transgenic reporter into putative PGCs in vitro. The Stella+ cells possess a transcriptional profile similar to embryo-derived PGCs, and like their counterparts in vivo, lose imprints in a time-dependent manner. Using inhibitory RNAs to screen candidate genes for effects on the development of Stella+ cells in vitro, we discovered that Lin28, a negative regulator of let-7 microRNA processing3-6, is essential for proper PGC development. We further show that Blimp1, a let-7 target and a master regulator of PGC specification7-9, can rescue the effect of Lin28-deficiency during PGC development, thereby establishing a mechanism of action for Lin28 during PGC specification. Over-expression of Lin28 promotes formation of Stella+ cells in vitro and PGCs in chimeric embryos, and is associated with human germ cell tumours. The differentiation of putative PGCs from ESCs in vitro recapitulates the early stages of gamete development in vivo, and provides an accessible system for discovering novel genes involved in germ cell development and malignancy. PMID:19578360

LIN7A depletion disrupts cerebral cortex development, contributing to intellectual disability in 12q21-deletion syndrome.

Directory of Open Access Journals (Sweden)

Ayumi Matsumoto

Full Text Available Interstitial deletion of 12q21 has been reported in four cases, which share several common clinical features, including intellectual disability (ID, low-set ears, and minor cardiac abnormalities. Comparative genomic hybridization (CGH analysis using the Agilent Human Genome CGH 180K array was performed with the genomic DNA from a two-year-old Japanese boy with these symptoms, as well as hypoplasia of the corpus callosum. Consequently, a 14 Mb deletion at 12q21.2-q21.33 (nt. 77 203 574-91 264 613 bp, which includes 72 genes, was detected. Of these, we focused on LIN7A, which encodes a scaffold protein that is important for synaptic function, as a possible responsible gene for ID, and we analyzed its role in cerebral cortex development. Western blotting analyses revealed that Lin-7A is expressed on embryonic day (E 13.5, and gradually increases in the mouse brain during the embryonic stage. Biochemical fractionation resulted in the enrichment of Lin-7A in the presynaptic fraction. Suppression of Lin-7A expression by RNAi, using in utero electroporation on E14.5, delayed neuronal migration on postnatal day (P 2, and Lin-7A-deficient neurons remained in the lower zone of the cortical plate and the intermediate zone. In addition, when Lin-7A was silenced in cortical neurons in one hemisphere, axonal growth in the contralateral hemisphere was delayed; development of these neurons was disrupted such that one half did not extend into the contralateral hemisphere after leaving the corpus callosum. Taken together, LIN7A is a candidate gene responsible for 12q21-deletion syndrome, and abnormal neuronal migration and interhemispheric axon development may contribute to ID and corpus callosum hypoplasia, respectively.

Functional comparison of the nematode Hox gene lin-39 in C. elegans and P. pacificus reveals evolutionary conservation of protein function despite divergence of primary sequences.

Science.gov (United States)

Grandien, K; Sommer, R J

2001-08-15

Hox transcription factors have been implicated in playing a central role in the evolution of animal morphology. Many studies indicate the evolutionary importance of regulatory changes in Hox genes, but little is known about the role of functional changes in Hox proteins. In the nematodes Pristionchus pacificus and Caenorhabditis elegans, developmental processes can be compared at the cellular, genetic, and molecular levels and differences in gene function can be identified. The Hox gene lin-39 is involved in the regulation of nematode vulva development. Comparison of known lin-39 mutations in P. pacificus and C. elegans revealed both conservation and changes of gene function. Here, we study evolutionary changes of lin-39 function using hybrid transgenes and site-directed mutagenesis in an in vivo assay using C. elegans lin-39 mutants. Our data show that despite the functional differences of LIN-39 between the two species, Ppa-LIN-39, when driven by Cel-lin-39 regulatory elements, can functionally replace Cel-lin-39. Furthermore, we show that the MAPK docking and phosphorylation motifs unique for Cel-LIN-39 are dispensable for Cel-lin-39 function. Therefore, the evolution of lin-39 function is driven by changes in regulatory elements rather than changes in the protein itself.

Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively

OpenAIRE

Nowak, Jakub Stanislaw; Hobor, Fruzsina; Downie Ruiz Velasco, Angela; Choudhury, Nila Roy; Heikel, Gregory; Kerr, Alastair; Ramos, Andres; Michlewski, Gracjan

2017-01-01

Lin28a inhibits the biogenesis of let-7 miRNAs by triggering the polyuridylation and degradation of their precursors by terminal uridylyltransferases TUT4/7 and 3’-5’ exoribonuclease Dis3l2, respectively. Previously, we showed that Lin28a also controls the production of neuro-specific miRNA-9 via a polyuridylation-independent mechanism. Here we reveal that the sequences and structural characteristics of pre-let-7 and pre-miRNA-9 are eliciting two distinct modes of binding to Lin28a. We presen...

Response to Niklasson's comment on Lin, et al. (2012) : "the relation between postural movement and bilateral motor integration".

Science.gov (United States)

Lin, Chin-Kai; Kuo, Bor-Chen; Wu, Huey-Min

2014-10-01

In the study of Lin, Wu, Lin, Wu, Wu, Kuo, and Yeung (2012 ), the relationship between the validity of postural movement and bilateral motor integration in terms of sensory integration theory was examined. Postural movement is the ability to use the antigravity postures required for stabilization of the neck, trunk and upper extremities via muscle co-contractions in the neck and upper extremities, and balance. Niklasson's (2013 ) comment argued that postural movement should include primitive reflexes in terms of the general abilities approach. Niklasson (2013 ) focused on the efficacy of the treatment rather than the theoretical frameworks implied in the therapeutic activities. For that purpose Lin, et al. (2012 ) used sensory integration as the theoretical foundation, and the relationship between postural movement and bilateral motor integration was assessed via empirical data. The result of Lin, et al. (2012 ) was offered as a theoretical reference for therapeutic activities.

The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury.

Science.gov (United States)

McDaniel, Kelly; Huang, Li; Sato, Keisaku; Wu, Nan; Annable, Tami; Zhou, Tianhao; Ramos-Lorenzo, Sugeily; Wan, Ying; Huang, Qiaobing; Francis, Heather; Glaser, Shannon; Tsukamoto, Hidekazu; Alpini, Gianfranco; Meng, Fanyin

2017-07-07

The let-7/Lin28 axis is associated with the regulation of key cellular regulatory genes known as microRNAs in various human disorders and cancer development. This study evaluated the role of the let-7/Lin28 axis in regulating a mesenchymal phenotype of hepatic stellate cells in alcoholic liver injury. We identified that ethanol feeding significantly down-regulated several members of the let-7 family in mouse liver, including let-7a and let-7b. Similarly, the treatment of human hepatic stellate cells (HSCs) with lipopolysaccharide (LPS) and transforming growth factor-β (TGF-β) significantly decreased the expressions of let-7a and let-7b. Conversely, overexpression of let-7a and let-7b suppressed the myofibroblastic activation of cultured human HSCs induced by LPS and TGF-β, as evidenced by repressed ACTA2 (α-actin 2), COL1A1 (collagen 1A1), TIMP1 (TIMP metallopeptidase inhibitor 1), and FN1 (fibronectin 1); this supports the notion that HSC activation is controlled by let-7. A combination of bioinformatics, dual-luciferase reporter assay, and Western blot analysis revealed that Lin28B and high-mobility group AT-hook (HMGA2) were the direct targets of let-7a and let-7b. Furthermore, Lin28B deficiency increased the expression of let-7a/let-7b as well as reduced HSC activation and liver fibrosis in mice with alcoholic liver injury. This feedback regulation of let-7 by Lin28B is verified in hepatic stellate cells isolated by laser capture microdissection from the model. The identification of the let-7/Lin28 axis as an important regulator of HSC activation as well as its upstream modulators and down-stream targets will provide insights into the involvement of altered microRNA expression in contributing to the pathogenesis of alcoholic liver fibrosis and novel therapeutic approaches for human alcoholic liver diseases. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

In honour of Georges Charpak

CERN Multimedia

More than 40 years ago, Georges Charpak invented the multi-wire proportional chamber, which revolutionized the detection of particles and which found applications in medicine. He was awarded the Nobel Prize in physics for this invention in 1992. On March 9, there will be a conference here at CERN to celebrate Georges Charpak’s 85th birthday and to pay tribute to his groundbreaking work. After an introduction by Rolf Heuer, CERN Director-General, Georges Charpak will give a short speech by videoconference. This will be followed by a talk on the invention of the multi-wire proportional chamber by Ioanis Giomataris of CEA-Saclay. You are invited to attend this special conference in the Main Auditorium, from 4.00 pm to 6.00 pm: http://indico.cern.ch/conferenceDisplay.py?confId=53188

Opposing Post-transcriptional Control of InR by FMRP and LIN-28 Adjusts Stem Cell-Based Tissue Growth

Directory of Open Access Journals (Sweden)

Arthur Luhur

2017-12-01

Full Text Available Summary: Although the intrinsic mechanisms that control whether stem cells divide symmetrically or asymmetrically underlie tissue growth and homeostasis, they remain poorly defined. We report that the RNA-binding protein fragile X mental retardation protein (FMRP limits the symmetric division, and resulting expansion, of the stem cell population during adaptive intestinal growth in Drosophila. The elevated insulin sensitivity that FMRP-deficient progenitor cells display contributes to their accelerated expansion, which is suppressed by the depletion of insulin-signaling components. This FMRP activity is mediated solely via a second conserved RNA-binding protein, LIN-28, known to boost insulin signaling in stem cells. Via LIN-28, FMRP controls progenitor cell behavior by post-transcriptionally repressing the level of insulin receptor (InR. This study identifies the stem cell-based mechanism by which FMRP controls tissue adaptation, and it raises the possibility that defective adaptive growth underlies the accelerated growth, gastrointestinal, and other symptoms that affect fragile X syndrome patients. : Luhur et al. report that FMRP acts via LIN-28 in progenitor cells to dampen the adaptive expansion of intestinal tissue in the fruit fly, raising the possibility that defective LIN28-mediated adaptive growth underlies some of the symptoms that affect fragile X syndrome patients. Keywords: FMRP, fmr1, LIN-28, insulin receptor, IIS, adaptive growth, tissue resizing, intestinal stem cell, insulin sensitivity

George Washington: A Grounded Leader

Science.gov (United States)

2011-04-08

placed in this book two years after the death of his father likely indicating he was now beginning to take possession of key documents that he...these truths would become part of the strong foundation upon which George would continue to build after the death ofhis father. As George moved into...men and women admired. He was both an I impressive horseman at a time when these talents truly counted, and became an extraordinarily graceful

Fragmented Encounters, Social Slippages: Lin Huiyin's "In Ninety-Nine Degree Heat"

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Carles Prado-Fonts

2010-01-01

Full Text Available The article reads Lin Huiyin’s short story “In Ninety-Nine Degree Heat” (1934 in relation to the context of 1930s China, as an innovative literary work which combines elements from both the Chinese and the Western traditions, and as a text which informs readers not only of the problematic of class and gender issues in 1930s Chinese society but also of the context of the liuxuesheng who returns to China –like Lin Huiyin herself. Focusing on questions like otherness, representation, and encounters, the essay analyzes how the episodic narrative structure of Lin’s short story echoes social and representational discourses in post-May Fourth China, at the same time that it explores issues such as social inequality, otherness and alienation, which were crucial to the liuxuesheng, and which reflect Lin’s own experience as a returned and alienated liuxuesheng at the time.

Overexpression of Lin28b in Neural Stem Cells is Insufficient for Brain Tumor Formation, but Induces Pathological Lobulation of the Developing Cerebellum.

Science.gov (United States)

Wefers, Annika K; Lindner, Sven; Schulte, Johannes H; Schüller, Ulrich

2017-02-01

LIN28B is a homologue of the RNA-binding protein LIN28A and regulates gene expression during development and carcinogenesis. It is strongly upregulated in a variety of brain tumors, such as medulloblastoma, embryonal tumor with multilayered rosettes (ETMR), atypical teratoid/rhabdoid tumor (AT/RT), or glioblastoma, but the effect of an in vivo overexpression of LIN28B on the developing central nervous system is unknown. We generated transgenic mice that either overexpressed Lin28b in Math1-positive cerebellar granule neuron precursors or in a broad range of Nestin-positive neural precursors. Sections of the cerebellar vermis from adult Math1-Cre::lsl-Lin28b mice had an additional subfissure in lobule IV. Vermes from p0 and p7 Nestin-Cre::lsl-Lin28b mice appeared normal, but we found a pronounced vermal hypersublobulation at p15 and p21 in these mice. Also, the external granule cell layer (EGL) was thicker at p15 than in controls, contained more proliferating cells, and persisted up to p21. Consistently, some Pax6- and NeuN-positive cells were present in the EGL of Nestin-Cre::lsl-Lin28b mice even at p21, and we detected more NeuN-positive granule neuron precursors in the molecular layer (ML) as compared to control. Finally, we found some residual Pax2-positive precursors of inhibitory interneurons in the ML of Nestin-Cre::lsl-Lin28b mice at p21, which have already disappeared in controls. We conclude that while overexpression of LIN28B in Nestin-positive cells does not lead to tumor formation, it results in a protracted development of granule cells and inhibitory interneurons and leads to a hypersublobulation of the cerebellar vermis.

George Soros : sõda terroriga on kohutav viga / George Soros ; interv. Külli-Riin Tigasson

Index Scriptorium Estoniae

Soros, George, 1930-

2006-01-01

Ilmunud ka: Infopress 15. dets. nr. 50 lk. 149. Miljardär ja filantroop George Soros vastab küsimustele, mis puudutavad tema raamatus "Ekslikkuse ajastu. Sõda terroriga ja selle tagajärjed" esitatud seisukohti. Ta leiab, et sõjakuulutamine terrorismile oli vale reaktsioon 11. septembri rünnakutele. George W. Bushi kursi muutumine Iraagiga seoses on tulnud liiga hilja. USA peab naasma oma traditsioonilise rolli juurde maailmas ja tegelema inimkonna suurimate probleemidega

93 une urbanisation linéaire, dynamique demographique et ...

African Journals Online (AJOL)

Mohand

d'Alger, dans l'ensemble Sahel-Mitidja sur un linéaire côtier de 2 km. Rattaché administrativement à la daira de ... connait une dynamique démographique remar- quable, dans sa périphérie orientale - composé de l'ensemble Sahel-. Mitidja ..... «Etude agro-pédologique de la plaine de la Mitidja». Florin B.; Semoud N. 2010.

Georges et le big bang

CERN Document Server

Hawking, Lucy; Parsons, Gary

2011-01-01

Georges et Annie, sa meilleure amie, sont sur le point d'assister à l'une des plus importantes expériences scientifiques de tous les temps : explorer les premiers instants de l'Univers, le Big Bang ! Grâce à Cosmos, leur super ordinateur, et au Grand Collisionneur de hadrons créé par Éric, le père d'Annie, ils vont enfin pouvoir répondre à cette question essentielle : pourquoi existons nous ? Mais Georges et Annie découvrent qu'un complot diabolique se trame. Pire, c'est toute la recherche scientifique qui est en péril ! Entraîné dans d'incroyables aventures, Georges ira jusqu'aux confins de la galaxie pour sauver ses amis...Une plongée passionnante au coeur du Big Bang. Les toutes dernières théories de Stephen Hawking et des plus grands scientifiques actuels.

CERN honours Georges Charpak

CERN Multimedia

2009-01-01

CERN pays tribute to the work of Georges Charpak at a colloquium in honour of his 85th birthday. var flash_video_player=get_video_player_path(); insert_player_for_external('Video/Public/Movies/2009/CERN-MOVIE-2009-008/CERN-MOVIE-2009-008-0753-kbps-480x360-25-fps-audio-64-kbps-44-kHz-stereo', 'mms://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2009/CERN-MOVIE-2009-008/CERN-MOVIE-2009-008-Multirate-200-to-753-kbps-480x360.wmv', 'false', 480, 360, 'https://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2009/CERN-MOVIE-2009-008/CERN-MOVIE-2009-008-posterframe-480x360-at-10-percent.jpg', '1167500', true, 'Video/Public/Movies/2009/CERN-MOVIE-2009-008/CERN-MOVIE-2009-008-0600-kbps-maxH-360-25-fps-audio-128-kbps-48-kHz-stereo.mp4'); Watch the video conference of Georges Charpak.   On 9 March CERN’s Main Auditorium was the venue for a fascinating and moving celebration marking the 85th birthday of Georges Charpak, who was awarded the Nobel Prize for Physics in 1992 for his inven...

Dynamiques complexes et morphogenèse Introduction aux sciences non linéaires

CERN Document Server

Misbah, Chaouqi

2011-01-01

Les sciences non linéaires ont pour objet l’ensemble des phénomènes dont l’analyse résiste au principe de superposition. Elles concernent en grande partie les systèmes dits « complexes » dont l’interaction et l’interdépendance entre les parties empêchent de prédire précisément l’évolution du système. Pour expliquer ces phénomènes, deux approches complémentaires ont été proposées : la théorie des bifurcations et la théorie des catastrophes. Mais la pleine compréhension et la modélisation de la non-linéarité restent chacune un défi pour les scientifiques du XXIe siècle. C’est dans la perspective d’accompagner tous ceux qui voudront le relever que ce livre a été conçu. Son objectif est d’exposer au lecteur le langage et le formalisme nécessaires à l’étude de la non-linéarité. Partant d’exemples simples, pour ensuite atteindre un niveau d’abstraction visant l’universalité, l’auteur explore les divers scénarios possibles de bifurcations et les catastr...

[Analysis of acid rain characteristics of Lin'an Regional Background Station using long-term observation data].

Science.gov (United States)

Li, Zheng-Quan; Ma, Hao; Mao, Yu-Ding; Feng, Tao

2014-02-01

Using long-term observation data of acid rain at Lin'an Regional Background Station (Lin'an RBS), this paper studied the interannual and monthly variations of acid rain, the reasons for the variations, and the relationships between acid rain and meteorological factors. The results showed that interannual variation of acid rain at Lin'an RBS had a general increasing trend in which there were two obvious intensifying processes and two distinct weakening processes, during the period ranging from 1985 to 2012. In last two decades, the monthly variation of acid rain at Lin'an RBS indicated that rain acidity and frequency of severe acid rain were increasing but the frequency of weak acid rain was decreasing when moving towards bilateral side months of July. Acid rain occurrence was affected by rainfall intensity, wind speed and wind direction. High frequency of severe acid rain and low frequency of weak acid rain were on days with drizzle, but high frequency of weak acid rain and low frequency of severe acid rain occurred on rainstorm days. With wind speed upgrading, the frequency of acid rain and the proportion of severe acid rain were declining, the pH value of precipitation was reducing too. Another character is that daily dominant wind direction of weak acid rain majorly converged in S-W section ,however that of severe acid rain was more likely distributed in N-E section. The monthly variation of acid rain at Lin'an RBS was mainly attributed to precipitation variation, the increasing and decreasing of monthly incoming wind from SSE-WSW and NWN-ENE sections of wind direction. The interannual variation of acid rain could be due to the effects of energy consumption raising and significant green policies conducted in Zhejiang, Jiangsu and Shanghai.

Georges Charpak street sign unveiled

CERN Multimedia

Paola Catapano

2011-01-01

While it might not be the only French street named in honour of the late Georges Charpak, who passed away in September 2010 at the age of 87, the street chosen by the mayor of Saint-Genis-Pouilly is certainly the only one located directly opposite the CERN "campus". The road overlooks buildings on the CERN Meyrin site, where Georges Charpak spent most of his career as a physicist, conducting the research that won him the Nobel Prize in Physics in 1992.   From left to right: Sigurd Lettow, Dominique Charpak and the mayor of Saint-Genis-Pouilly. The unveiling took place on 17 October and was organised by the mayor of Saint-Genis-Pouilly. George Charpak’s wife, Dominique, and Sigurd Lettow, CERN Director of Administration and General Infrastructure, attended what was an intimate and touching ceremony. The mayor’s speech at the event praised Georges’ commitment to scientific education. The highlight of the event, however, was a witty and humorous ...

Georges Charpak, Nobel Physics Prize 1992

Energy Technology Data Exchange (ETDEWEB)

Anon.

1992-12-15

Wednesday 14 October looked like being a day like any other for detector specialist Georges Charpak. Except he had an unwelcome appointment with the dentist early that afternoon. Late that morning he was able to telephone to cancel the appointment. 'I have a small problem...', he explained. The problem was the announcement that Georges Charpak receives 1992's most prestigious award for physics.

Primordial dwarfism gene maintains Lin28 expression to safeguard embryonic stem cells from premature differentiation.

Science.gov (United States)

Dai, Qian; Luan, Guangxin; Deng, Li; Lei, Tingjun; Kang, Han; Song, Xu; Zhang, Yujun; Xiao, Zhi-Xiong; Li, Qintong

2014-05-08

Primordial dwarfism (PD) is characterized by global growth failure, both during embryogenesis and postnatally. Loss-of-function germline mutations in La ribonucleoprotein domain family, member 7 (LAPR7) have recently been linked to PD. Paradoxically, LARP7 deficiency was previously assumed to be associated with increased cell growth and proliferation via activation of positive transcription elongation factor b (P-TEFb). Here, we show that Larp7 deficiency likely does not significantly increase P-TEFb activity. We further discover that Larp7 knockdown does not affect pluripotency but instead primes embryonic stem cells (ESCs) for differentiation via downregulation of Lin28, a positive regulator of organismal growth. Mechanistically, we show that Larp7 interacts with a poly(A) polymerase Star-PAP to maintain Lin28 mRNA stability. We propose that proper regulation of Lin28 and PTEFb is essential for embryonic cells to achieve a sufficient number of cell divisions prior to differentiation and ultimately to maintain proper organismal size. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

New explicit and exact solutions of the Benney–Kawahara–Lin equation

International Nuclear Information System (INIS)

Yuan-Xi, Xie

2009-01-01

In this paper, we present a combination method of constructing the explicit and exact solutions of nonlinear partial differential equations. And as an illustrative example, we apply the method to the Benney–Kawahara–Lin equation and derive its many explicit and exact solutions which are all new solutions. (general)

George A. Olah, Carbocation and Hydrocarbon Chemistry

Science.gov (United States)

dropdown arrow Site Map A-Z Index Menu Synopsis George A. Olah, Carbocation and Hydrocarbon Chemistry George Olah received the 1994 Nobel Prize in Chemistry "for his contribution to carbocation chemistry" and his 'role in the chemistry of hydrocarbons. In particular, he developed superacids

Välinäituse stendid = Outdoor exhibition stands / Gert Sarv, Galina Burnakova

Index Scriptorium Estoniae

Sarv, Gert, 1971-

2013-01-01

Eesti Sisearhitektide Liidu 2012. aasta parima eseme preemia pälvinud välinäituse stendidest Vanasadama Admiraliteedi basseini kaldapealsel. Autorid: Gert Sarv, Galina Burnakova, Loreida Hein. Sisearhitekti ja ESLi aastapreemiate žürii liikme Tea Tammelaane arvamus

Georges Charpak, Nobel Physics Prize 1992

International Nuclear Information System (INIS)

Anon.

1992-01-01

Wednesday 14 October looked like being a day like any other for detector specialist Georges Charpak. Except he had an unwelcome appointment with the dentist early that afternoon. Late that morning he was able to telephone to cancel the appointment. 'I have a small problem...', he explained. The problem was the announcement that Georges Charpak receives 1992's most prestigious award for physics

Georges Charpak and his multiwire chamber

CERN Multimedia

1970-01-01

In 1968, Georges Charpak developed the 'multiwire proportional chamber', a gas-filled box with a large number of parallel detector wires, each connected to individual amplifiers. Linked to a computer, it could achieve a counting rate a thousand times better than existing techniques - without a camera in sight. From left to right, Georges Charpak, Fabio Sauli and Jean-Claude Santiard working on a multiwire chamber in 1970.

George and the unbreakable code

CERN Document Server

Hawking, Lucy; Parsons, Gary

2014-01-01

George and his best friend Annie haven't had any space adventures for a while and they're missing the excitement. But not for long . . . Seriously strange things start happening. Banks are handing out free money; supermarkets can't charge for their produce so people are getting free food; and aircraft are refusing to fly. It looks like the world's biggest and best computers have all been hacked. George and Annie will travel further into space than ever before in order to find out who is behind it.

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans.

Science.gov (United States)

Reddien, Peter W; Andersen, Erik C; Huang, Michael C; Horvitz, H Robert

2007-04-01

The genes egl-1, ced-9, ced-4, and ced-3 play major roles in programmed cell death in Caenorhabditis elegans. To identify genes that have more subtle activities, we sought mutations that confer strong cell-death defects in a genetically sensitized mutant background. Specifically, we screened for mutations that enhance the cell-death defects caused by a partial loss-of-function allele of the ced-3 caspase gene. We identified mutations in two genes not previously known to affect cell death, dpl-1 and mcd-1 (modifier of cell death). dpl-1 encodes the C. elegans homolog of DP, the human E2F-heterodimerization partner. By testing genes known to interact with dpl-1, we identified roles in cell death for four additional genes: efl-1 E2F, lin-35 Rb, lin-37 Mip40, and lin-52 dLin52. mcd-1 encodes a novel protein that contains one zinc finger and that is synthetically required with lin-35 Rb for animal viability. dpl-1 and mcd-1 act with efl-1 E2F and lin-35 Rb to promote programmed cell death and do so by regulating the killing process rather than by affecting the decision between survival and death. We propose that the DPL-1 DP, MCD-1 zinc finger, EFL-1 E2F, LIN-35 Rb, LIN-37 Mip40, and LIN-52 dLin52 proteins act together in transcriptional regulation to promote programmed cell death.

Submission to the Georges Bank Review Panel

Energy Technology Data Exchange (ETDEWEB)

Rankin, E.; Butler, M.; Church, T.

1999-01-01

The Georges Bank, off southwestern Nova Scotia, is one of the most biologically productive continental shelf ecosystems in the world. It supports a wide diversity of species, including many seabirds. In 1988, federal and provincial legislation placed a moratorium on petroleum exploration and drilling on the Georges Bank, directing the ministers of Natural Resources Canada, and of the Nova Scotia Department of Natural Resources to make a decision regarding the moratorium by January 1, 2000. This report by the Ecology Action Centre (EAC) asks the Georges Bank Review Panel to recommend extending the moratorium on Georges Bank and adjacent areas until 2012, in part to match the American moratorium. Other reasons why the panel made this recommendation were explored. The principal reason is the EAC concern that when the moratorium is lifted, several oil and gas developments will proceed in this ecologically significant offshore area that could result in the loss of the ecological integrity of Georges Bank. The EAC contends that before oil and gas development in the region could begin, the following issues would have to be resolved: (1) disposal of drill muds and cuttings, (2) volume and disposal of produced water, (3) effects of small and large spills, (4) impact of seismic activities on whales and turtles, and (5) carbon dioxide emission through venting and flaring. Also, the EAC does not believe that developing Georges Bank will create as many jobs in the affected communities as some people suggest. Lifting the moratorium by Canada would also frustrate American environmental goals, as well as compromise Canada`s position in international environmental partnerships such as the Gulf of Maine Council. 19 refs., tabs., figs.

Submission to the Georges Bank Review Panel

International Nuclear Information System (INIS)

Rankin, E.; Butler, M.; Church, T.

1999-01-01

The Georges Bank, off southwestern Nova Scotia, is one of the most biologically productive continental shelf ecosystems in the world. It supports a wide diversity of species, including many seabirds. In 1988, federal and provincial legislation placed a moratorium on petroleum exploration and drilling on the Georges Bank, directing the ministers of Natural Resources Canada, and of the Nova Scotia Department of Natural Resources to make a decision regarding the moratorium by January 1, 2000. This report by the Ecology Action Centre (EAC) asks the Georges Bank Review Panel to recommend extending the moratorium on Georges Bank and adjacent areas until 2012, in part to match the American moratorium. Other reasons why the panel made this recommendation were explored. The principal reason is the EAC concern that when the moratorium is lifted, several oil and gas developments will proceed in this ecologically significant offshore area that could result in the loss of the ecological integrity of Georges Bank. The EAC contends that before oil and gas development in the region could begin, the following issues would have to be resolved: (1) disposal of drill muds and cuttings, (2) volume and disposal of produced water, (3) effects of small and large spills, (4) impact of seismic activities on whales and turtles, and (5) carbon dioxide emission through venting and flaring. Also, the EAC does not believe that developing Georges Bank will create as many jobs in the affected communities as some people suggest. Lifting the moratorium by Canada would also frustrate American environmental goals, as well as compromise Canada's position in international environmental partnerships such as the Gulf of Maine Council. 19 refs., tabs., figs

GENII-LIN: a Multipurpose Health Physics Code Built on GENII-1.485

Directory of Open Access Journals (Sweden)

Marco Sumini

2006-10-01

Full Text Available The aim of the GENII-LIN project was to develop an open source multipurpose health physics code running on Linux platform, for calculating radiation dose and risk from radionuclides released to the environment. The general features of the GENII-LIN system include [1] capabilities for calculating radiation dose both for acute and chronic releases, with options for annual dose, committed dose and accumulated dose [2] capabilities for evaluating exposure pathways including direct exposure via water (swimming, boating, fishing, soil (buried and surface sources and air (semi-infinite cloud and finite cloud model, inhalation pathways and ingestion pathways. The release scenarios considered are: - acute release to air, from ground level or elevated sources, or to water; - chronic release to air, from ground level or elevated sources, or to water; - initial contamination of soil or surfaces. Keywords: radiation protection, Linux, health physics, risk analysis.

Using Lin's method to solve Bykov's problems

Science.gov (United States)

Knobloch, Jürgen; Lamb, Jeroen S. W.; Webster, Kevin N.

2014-10-01

We consider nonwandering dynamics near heteroclinic cycles between two hyperbolic equilibria. The constituting heteroclinic connections are assumed to be such that one of them is transverse and isolated. Such heteroclinic cycles are associated with the termination of a branch of homoclinic solutions, and called T-points in this context. We study codimension-two T-points and their unfoldings in Rn. In our consideration we distinguish between cases with real and complex leading eigenvalues of the equilibria. In doing so we establish Lin's method as a unified approach to (re)gain and extend results of Bykov's seminal studies and related works. To a large extent our approach reduces the study to the discussion of intersections of lines and spirals in the plane. Case (RR): Under open conditions on the eigenvalues, there exist open sets in parameter space for which there exist periodic orbits close to the heteroclinic cycle. In addition, there exist two one-parameter families of homoclinic orbits to each of the saddle points p1 and p2.See Theorem 2.1 and Proposition 2.2 for precise statements and Fig. 2 for bifurcation diagrams. Cases (RC) and (CC): At the bifurcation point μ=0 and for each N≥2, there exists an invariant set S0N close to the heteroclinic cycle on which the first return map is topologically conjugated to a full shift on N symbols. For any fixed N≥2, the invariant set SμN persists for |μ| sufficiently small.In addition, there exist infinitely many transversal and non-transversal heteroclinic orbits connecting the saddle points p1 and p2 in a neighbourhood of μ=0, as well as infinitely many one-parameter families of homoclinic orbits to each of the saddle points.For full statements of the results see Theorem 2.3 and Propositions 2.4, 2.5 and Fig. 3 for bifurcation diagrams. The dynamics near T-points has been studied previously by Bykov [6-10], Glendinning and Sparrow [20], Kokubu [27,28] and Labouriau and Rodrigues [30,31,38]. See also the surveys

Hommage à Georges Duby

Directory of Open Access Journals (Sweden)

Dominique Iogna-Prat

2006-09-01

Full Text Available Dix ans après le décès du grand maître des études médiévales, le temps est sans nul doute venu de revisiter l’œuvre de Georges Duby et d’en discuter l’actualité du point de vue de l’histoire sociale du Moyen Âge. À une seule exception – Claudie Amado, qui fut son assistante –, les historiens invités n’ont pas travaillé au contact direct de Georges Duby ; il leur a été demandé de faire, chacun dans leur domaine, le bilan des apports du maître et de mettre en perspective ses principales thèses ...

Topografia ficcional: a construção do espaço nos manuscritos de Osman Lins

Directory of Open Access Journals (Sweden)

Francisco José Gonçalves Lima Rocha

2013-01-01

Full Text Available In the construction of the narrative space of his final, unfinished novel, A cabeça levada em triunfo, Osman Lins operates both verbal, with notes planning, as iconically, through drawings. Will try to show that the author’s purpose is to clarify the topography of the work, because it establishes and harmonizes the technical functions - ie, like space, says Osman Lins, “frame” the character – and symbolic means, ie. how the space reflects, like all other elements of the work, the questioning of the head-body dichotomy.

On the reduction of generalized polylogarithms to Li_n and Li_2_,_2 and on the evaluation thereof

International Nuclear Information System (INIS)

Frellesvig, Hjalte; Tommasini, Damiano; Wever, Christopher

2016-01-01

We give expressions for all generalized polylogarithms up to weight four in terms of the functions log, Li_n, and Li_2_,_2, valid for arbitrary complex variables. Furthermore we provide algorithms for manipulation and numerical evaluation of Li_n and Li_2_,_2, and add codes in Mathematica and C++ implementing the results. With these results we calculate a number of previously unknown integrals, which we add in appendix C.

Lin28B promotes Müller glial cell de-differentiation and proliferation in the regenerative rat retinas

Science.gov (United States)

Tao, Zui; Zhao, Chen; Jian, Qian; Gillies, Mark; Xu, Haiwei; Yin, Zheng Qin

2016-01-01

Retinal regeneration and repair are severely impeded in higher mammalian animals. Although Müller cells can be activated and show some characteristics of progenitor cells when injured or under pathological conditions, they quickly form gliosis scars. Unfortunately, the basic mechanisms that impede retinal regeneration remain unknown. We studied retinas from Royal College of Surgeon (RCS) rats and found that let-7 family molecules, let-7e and let-7i, were significantly overexpressed in Müller cells of degenerative retinas. It demonstrated that down-regulation of the RNA binding protein Lin28B was one of the key factors leading to the overexpression of let-7e and let-7i. Lin28B ectopic expression in the Müller cells suppressed overexpression of let-7e and let-7i, stimulated and mobilized Müller glia de-differentiation, proliferation, promoted neuronal commitment, and inhibited glial fate acquisition of de-differentiated Müller cells. ERG recordings revealed that the amplitudes of a-wave and b-wave were improved significantly after Lin28B was delivered into the subretinal space of RCS rats. In summary, down-regulation of Lin28B as well as up-regulation of let-7e and let-7i may be the main factors that impede Müller cell de-differentiation and proliferation in the retina of RCS rats. PMID:27384999

The philosophy of Hans-Georg Gadamer / Wolfgang Drechsler

Index Scriptorium Estoniae

Drechsler, Wolfgang, 1963-

1998-01-01

Rets.rmt.: The philosophy of Hans-Georg Gadamer : a review of the philosophy of Hans-Georg Gadamer / Lewis Edwin Hahn, ed. Chicago and La Salle, IL: Open Court, 1997. (The Library of Living Philosophers, vol. XXIV)

A role for the malignant brain tumour (MBT domain protein LIN-61 in DNA double-strand break repair by homologous recombination.

Directory of Open Access Journals (Sweden)

Nicholas M Johnson

Full Text Available Malignant brain tumour (MBT domain proteins are transcriptional repressors that function within Polycomb complexes. Some MBT genes are tumour suppressors, but how they prevent tumourigenesis is unknown. The Caenorhabditis elegans MBT protein LIN-61 is a member of the synMuvB chromatin-remodelling proteins that control vulval development. Here we report a new role for LIN-61: it protects the genome by promoting homologous recombination (HR for the repair of DNA double-strand breaks (DSBs. lin-61 mutants manifest numerous problems associated with defective HR in germ and somatic cells but remain proficient in meiotic recombination. They are hypersensitive to ionizing radiation and interstrand crosslinks but not UV light. Using a novel reporter system that monitors repair of a defined DSB in C. elegans somatic cells, we show that LIN-61 contributes to HR. The involvement of this MBT protein in HR raises the possibility that MBT-deficient tumours may also have defective DSB repair.

Aktjorõ filma "Georg" vpervõje sobralis vmestje

Index Scriptorium Estoniae

2006-01-01

Vene näitlejanna Anastasia Makejeva ja eesti laulev näitleja Marko Matvere, kes mängivad Peeter Simmi töös olevas mängufilmis "Georg" Georg Otsa ja tema teist abikaasat Asta Otsa, alustavad homme filmivõtteid

Gilbert ja George lasevad oma kunstiteose alla laadida

Index Scriptorium Estoniae

2007-01-01

9.05.2007 öösel on kõigil soovijail võimalik tasuta interneti vahendusel omandada Londonis tegutseva kunstnikepaari Gilbert & George (Gilbert Proesch ja George Passmore) teos "Planed". Aadressid: www.bbc.co.uk/imagine ja www.guardian.co.uk/art

Georges Bank: a leaky incubator of Alexandrium fundyense blooms.

Science.gov (United States)

McGillicuddy, D J; Townsend, D W; Keafer, B A; Thomas, M A; Anderson, D M

2014-05-01

A series of oceanographic surveys on Georges Bank document variability of populations of the toxic dinoflagellate Alexandrium fundyense on time scales ranging from synoptic to seasonal to interannual. Blooms of A. fundyense on Georges Bank can reach concentrations on the order of 10 4 cells l -1 , and are generally bank-wide in extent. Georges Bank populations of A. fundyense appear to be quasi-independent of those in the adjacent coastal Gulf of Maine, insofar as they occupy a hydrographic niche that is colder and saltier than their coastal counterparts. In contrast to coastal populations that rely on abundant resting cysts for bloom initiation, very few cysts are present in the sediments on Georges Bank. Bloom dynamics must therefore be largely controlled by the balance between growth and mortality processes, which are at present largely unknown for this population. Based on correlations between cell abundance and nutrient distributions, ammonium appears to be an important source of nitrogen for A. fundyense blooms on Georges Bank.

Cryptanalysis of Lin et al.'s Efficient Block-Cipher-Based Hash Function

NARCIS (Netherlands)

Liu, Bozhong; Gong, Zheng; Chen, Xiaohong; Qiu, Weidong; Zheng, Dong

2010-01-01

Hash functions are widely used in authentication. In this paper, the security of Lin et al.'s efficient block-cipher-based hash function is reviewed. By using Joux's multicollisions and Kelsey et al.'s expandable message techniques, we find the scheme is vulnerable to collision, preimage and second

Single-tube linear DNA amplification (LinDA) for robust ChIP-seq

NARCIS (Netherlands)

Shankaranarayanan, P.; Mendoza-Parra, M.A.; Walia, M.; Wang, L.; Li, N.; Trindade, L.M.; Gronemeyer, H.

2011-01-01

Genome-wide profiling of transcription factors based on massive parallel sequencing of immunoprecipitated chromatin (ChIP-seq) requires nanogram amounts of DNA. Here we describe a high-fidelity, single-tube linear DNA amplification method (LinDA) for ChIP-seq and reChIP-seq with picogram DNA amounts

George's secret key to the universe

CERN Document Server

Hawking, Lucy; Galfard, Christophe; Parsons, Gary

2007-01-01

In their bestselling book for young readers, noted physicist Stephen Hawking and his daughter, Lucy, provide a grand and funny adventure that explains fascinating information about our universe, including Dr. Hawking's latest ideas about black holes. It's the story of George, who's taken through the vastness of space by a scientist, his daughter, and their super-computer named Cosmos. George's Secret Key to the Universe was a New York Times bestseller and a selection of Al's Book Club on the Today show.

Georges Besse 2. A new era for enrichment

International Nuclear Information System (INIS)

2009-01-01

Since 1978, AREVA group subsidiary EURODIF's Georges Besse plant has been using gaseous diffusion to enrich uranium and meet the requirements of electricity utilities. Georges Besse II plant, which will use far less electricity, will replace George Besse not so long. The Georges Besse II plant is located on the Tricastin nuclear site in southern France. AREVA ensure delivery of uranium enrichment services in accordance with customer expectations. AREVA obtained the right to use URENCO's centrifugation technology on July 3, 2006. This is the process to be used at Georges Besse II. The new uranium enrichment plant will comprise two enrichment units, with a total production capacity of 7.5 million separative work units, which can be extended to 11 million if needed. Each enrichment unit will include: a Centrifuge Assembly Building (CAB), a Centrifuge Utility Building (CUB) with offices and control room, annexes for purification, supply and extraction of uranium hexafluoride (UF 6 ), modules containing the halls that house the centrifuge cascades. The modular design of the Georges Besse II plant will allow production in the first cascade where as the others cascades are build. The first cascade should be operational in the first half of 2009. At an overall cost of 3 billion euros, this project is one of the largest investments of the decade in France On November 24, 2003, AREVA and URENCO signed an agreement under which AREVA would buy 50% of the shares in the Enrichment Technology Company (ETC), which designs and manufactures centrifuges

The gga-let-7 family post-transcriptionally regulates TGFBR1 and LIN28B during the differentiation process in early chick development.

Science.gov (United States)

Lee, Sang In; Jeon, Mi-Hyang; Kim, Jeom Sun; Jeon, Ik-Soo; Byun, Sung June

2015-12-01

Early chick embryogenesis is governed by a complex mechanism involving transcriptional and post-transcriptional regulation, although how post-transcriptional processes influence the balance between pluripotency and differentiation during early chick development have not been previously investigated. Here, we characterized the microRNA (miRNA) signature associated with differentiation in the chick embryo, and found that as expression of the gga-let-7 family increases through early development, expression of their direct targets, TGFBR1 and LIN28B, decreases; indeed, gga-let-7a-5p and gga-let-7b miRNAs directly bind to TGFBR1 and LIN28B transcripts. Our data further indicate that TGFBR1 and LIN28B maintain pluripotency by regulating POUV, NANOG, and CRIPTO. Therefore, gga-let-7 miRNAs act as post-transcriptional regulators of differentiation in blastodermal cells by repressing the expression of the TGFBR1 and LIN28B, which intrinsically controls blastodermal cell differentiation in early chick development. © 2015 Wiley Periodicals, Inc.

Curcumin Inhibits LIN-28A through the Activation of miRNA-98 in the Lung Cancer Cell Line A549.

Science.gov (United States)

Liu, Wei-Lun; Chang, Jia-Ming; Chong, Inn-Wen; Hung, Yi-Li; Chen, Yung-Hsiang; Huang, Wen-Tsung; Kuo, Hsuan-Fu; Hsieh, Chong-Chao; Liu, Po-Len

2017-06-03

Metastasis is common in lung cancer and is associated with poor clinical outcomes and increased mortality. Curcumin is a natural anti-cancer agent that inhibits the metastasis of various cancers by modulating the expression of micro (mi) RNAs such as miR-98, which acts as a tumor suppressor. This study investigated the effect of curcumin on miR-98 expression and in vitro cell line growth and invasiveness in lung cancer. Curcumin treatment enhanced the expression of miR-98 and reduced that of the miR-98 target gene LIN28A as well as matrix metalloproteinase ( MMP ) 2 and MMP9 in vitro and in vivo. MiR-98 overexpression suppressed lung cancer cell migration and invasion by inhibiting LIN28A-induced MMP2 and MMP9 expression. Meanwhile, LIN28A level was downregulated by overexpression of miR-98 mimic. Induction of miR-98 by curcumin treatment suppressed MMP2 and MMP9 by targeting LIN28A. These findings provide insight into the mechanisms by which curcumin suppresses lung cancer cell line growth in vitro and in vivo and invasiveness in vitro.

Limb anomalies in DiGeorge and CHARGE syndromes

Energy Technology Data Exchange (ETDEWEB)

Prasad, C.; Quackenbush, E.J.; Whiteman, D.; Korf, B. [Harvard Medical School, Boston, MA (United States)

1997-01-20

Limb anomalies are not common in the DiGeorge or CHARGE syndromes. We describe limb anomalies in two children, one with DiGeorge and the other with CHARGE syndrome. Our first patient had a bifid left thumb, Tetralogy of Fallot, absent thymus, right facial palsy, and a reduced number of T-cells. A deletion of 22q11 was detected by fluorescence in situ hybridization (FISH). The second patient, with CHARGE syndrome, had asymmetric findings that included right fifth finger clinodactyly, camptodactyly, tibial hemimelia and dimpling, and severe club-foot. The expanded spectrum of the DiGeorge and CHARGE syndromes includes limb anomalies. 14 refs., 4 figs.

An Effective Implementation of K-opt Moves for the Lin-Kernighan TSP Heuristic

DEFF Research Database (Denmark)

Helsgaun, Keld

Local search with k-change neighborhoods, k-opt, is the most widely used heuristic method for the traveling salesman problem (TSP). This report presents an effective implementation of k-opt for the Lin- Kernighan TSP heuristic. The effectiveness of the implementation is demonstrated with extensive...

Georges Paillard 1932-2004 - French version only

CERN Multimedia

2004-01-01

J'ai eu le plaisir de rencontrer Georges en juillet 1959 au groupe Magnet de la division PS au moment où le centième et dernier aimant venait d'être installé dans l'anneau. Le groupe commençait déjà à s'orienter vers de nouveaux projets et mon premier travail avec Georges consista dans des essais de tubes flash de puissance pour la future chambre à bulles. Ensuite, bien que travaillant dans des domaines différents, mais toujours dans les mêmes divisions, nous ne nous sommes jamais perdus de vue. J'ai rencontré Georges en janvier 1961 au laboratoire d'électronique de la division NPA. Georges avait déjà six ans de CERN : c'était un ancien. Au début, il y eut la chambre à « boules ». Le chef de la division NPA, M. Colin Ramm, australien, éprouvait une certaine difficulté à prononcer le « u » français et une machine classique de la physique nucléaire est devenue l'unique chambre à « boules » jamais construite. Chambre qui connut son heure de gloire puisqu'elle enreg...

Weak activity of haloalkane dehalogenase LinB with 1,2,3-trichloropropane revealed by X-Ray crystallography and microcalorimetry.

Science.gov (United States)

Monincová, Marta; Prokop, Zbynek; Vévodová, Jitka; Nagata, Yuji; Damborsky, Jirí

2007-03-01

1,2,3-Trichloropropane (TCP) is a highly toxic and recalcitrant compound. Haloalkane dehalogenases are bacterial enzymes that catalyze the cleavage of a carbon-halogen bond in a wide range of organic halogenated compounds. Haloalkane dehalogenase LinB from Sphingobium japonicum UT26 has, for a long time, been considered inactive with TCP, since the reaction cannot be easily detected by conventional analytical methods. Here we demonstrate detection of the weak activity (k(cat) = 0.005 s(-1)) of LinB with TCP using X-ray crystallography and microcalorimetry. This observation makes LinB a useful starting material for the development of a new biocatalyst toward TCP by protein engineering. Microcalorimetry is proposed to be a universal method for the detection of weak enzymatic activities. Detection of these activities is becoming increasingly important for engineering novel biocatalysts using the scaffolds of proteins with promiscuous activities.

Weak Activity of Haloalkane Dehalogenase LinB with 1,2,3-Trichloropropane Revealed by X-Ray Crystallography and Microcalorimetry▿

Science.gov (United States)

Monincová, Marta; Prokop, Zbyněk; Vévodová, Jitka; Nagata, Yuji; Damborský, Jiří

2007-01-01

1,2,3-Trichloropropane (TCP) is a highly toxic and recalcitrant compound. Haloalkane dehalogenases are bacterial enzymes that catalyze the cleavage of a carbon-halogen bond in a wide range of organic halogenated compounds. Haloalkane dehalogenase LinB from Sphingobium japonicum UT26 has, for a long time, been considered inactive with TCP, since the reaction cannot be easily detected by conventional analytical methods. Here we demonstrate detection of the weak activity (kcat = 0.005 s−1) of LinB with TCP using X-ray crystallography and microcalorimetry. This observation makes LinB a useful starting material for the development of a new biocatalyst toward TCP by protein engineering. Microcalorimetry is proposed to be a universal method for the detection of weak enzymatic activities. Detection of these activities is becoming increasingly important for engineering novel biocatalysts using the scaffolds of proteins with promiscuous activities. PMID:17259360

Moving towards first science with the St. George recoil separator

Science.gov (United States)

Meisel, Zachary; Berg, G. P. A.; Gilardy, G.; Moran, M.; Schmitt, J.; Seymour, C.; Stech, E.; Couder, M.

2015-10-01

The St. George recoil mass separator has recently been coupled to the 5MV St. Ana accelerator at the University of Notre Dame's Nuclear Science Lab. St. George is a unique tool designed to measure radiative alpha-capture reactions for nuclei up to A = 40 in inverse kinematics in order to directly obtain cross sections required for astrophysical models of stellar and explosive helium burning. Commissioning of St. George is presently taking place with primary beams of hydrogen, helium, and oxygen. In this presentation, results will be shown for the measured energy acceptance of St. George, which compare favorably to COSY results when employing the calculated optimal ion-optical settings. Additionally, future plans will be discussed, such as assessing the angular acceptance of St. George and the re-integration of HiPPO at the separator target position to provide a dense, windowless helium gas-jet target. The material presented in this work is partially supported by the National Science Foundation Grant No. 1419765.

A Post-Modern George.

Science.gov (United States)

Hunter, Robert S.

2000-01-01

Presents an art project in which students create postmodern portraits of George Washington in the style of Andy Warhol's pop-art portraits. Each portrait incorporates a fact and six symbols associated with Washington. Describes the project in detail and lists the materials and project objectives. (CMK)

LIN28B polymorphisms are associated with central precocious puberty and early puberty in girls

Directory of Open Access Journals (Sweden)

Sung Won Park

2012-10-01

Full Text Available &lt;B&gt;Purpose:&lt;/B&gt; Single-nucleotide polymorphism (SNP markers within &lt;i&gt;LIN28B&lt;/i&gt; have been reported to be related to the timing of pubertal growth. However, no study has investigated the frequency of genetic markers in girls with precocious puberty (PP or early puberty (EP. This study aimed to determine the frequency of putative genetic markers in girls with PP or EP. &lt;B&gt;Methods:&lt;/B&gt; Genomic DNAs were obtained from 77 and 109 girls that fulfilled the criteria for PP and EP, respectively. The controls in this study were 144 healthy volunteers between 20 and 30 years of age. The haplotypes were reconstructed using 11 SNPs of &lt;i&gt;LIN28B&lt;/i&gt;, and haplotype association analysis was performed. The haplotype frequencies were compared. Differences in the clinical and laboratory parameters were analyzed according to the haplotype dosage. &lt;B&gt;Results:&lt;/B&gt; Eleven SNPs in &lt;i&gt;LIN28B&lt;/i&gt; were all located in a block that was in linkage disequilibrium. The haplotype could be reconstructed using 2 representative SNPs, rs4946651 and rs369065. The AC haplotype was less frequently observed in the PP group than in the controls (0.069 vs. 0.144, &lt;I&gt;P&lt;/I&gt;=0.010. The trend that girls with non-AC haplotypes tended to have earlier puberty onset (&lt;I&gt;P&lt;/I&gt;=0.037 was illustrated even in the EP+PP patient group by Kaplan-Meier analysis. &lt;B&gt;Conclusion:&lt;/B&gt; The results of the present study showed that non-AC haplotypes of &lt;i&gt;LIN28B&lt;/i&gt;had a significant association with PP in girls.

Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes.

Directory of Open Access Journals (Sweden)

Paul D Goetsch

2017-11-01

Full Text Available The DREAM (Dp/Retinoblastoma(Rb-like/E2F/MuvB transcriptional repressor complex acts as a gatekeeper of the mammalian cell cycle by establishing and maintaining cellular quiescence. How DREAM's three functional components, the E2F-DP heterodimer, the Rb-like pocket protein, and the MuvB subcomplex, form and function at target gene promoters remains unknown. The current model invokes that the pocket protein links E2F-DP and MuvB and is essential for gene repression. We tested this model by assessing how the conserved yet less redundant DREAM system in Caenorhabditis elegans is affected by absence of the sole C. elegans pocket protein LIN-35. Using a LIN-35 protein null mutant, we analyzed the assembly of E2F-DP and MuvB at promoters that are bound by DREAM and the level of expression of those "DREAM target genes" in embryos. We report that LIN-35 indeed mediates the association of E2F-DP and MuvB, a function that stabilizes DREAM subunit occupancy at target genes. In the absence of LIN-35, the occupancy of E2F-DP and MuvB at most DREAM target genes decreases dramatically and many of those genes become upregulated. The retention of E2F-DP and MuvB at some target gene promoters in lin-35 null embryos allowed us to test their contribution to DREAM target gene repression. Depletion of MuvB, but not E2F-DP, in the sensitized lin-35 null background caused further upregulation of DREAM target genes. We conclude that the pocket protein functions primarily to support MuvB-mediated repression of DREAM targets and that transcriptional repression is the innate function of the evolutionarily conserved MuvB complex. Our findings provide important insights into how mammalian DREAM assembly and disassembly may regulate gene expression and the cell cycle.

EDITORIAL: George W Series Memorial Essays

Science.gov (United States)

Dodd, J. N.

1997-01-01

I would like to recall my experiences when I joined George Series when on study leave from the University of Otago in 1959. Like George, we had decided, some years previously, to pursue the line of research opened up by the double-resonance experiment of Brossel and Bitter. Up to that time both groups had been applying the new technique to traditional spectroscopic problems, those of measuring the fine structure, hyperhe structure, g-factors and nuclear moments. But here, in Oxford, was something new and exciting - experiments that studied the nature of light itself, questioning some long-held views. George had come to the view that, in a double-resonance experiment, one could demonstrate the inner coherence that could exist between superposition states of an atom. He, and his students Wilf Fox and Mike Taylor, had already obtained promising evidence; but he needed more definite results if he was going to allay the doubts and suspicions of some others in the Clarendon. At the time, people generally thought that light, being a superposition of radiations from many atoms with no obvious phase relation to each other, was an incoherent wave phenomenon. One could observe small scale coherence (for example, in the Young interference experiment) but it would be largely concealed by the incoherent nature of the radiation from many atoms in a source. In the experiments that had been performed the coherence was introduced between a pair of excited states (Zeeman sub-states) by the application of an oscillating magnetic field - was it not likely, according to the doubters, that the modulation observed in the fluorescence was due to "pick-up" in the amplifiers from the source of oscillations? George had to prove that this was not the cause. I well remember him saying at the time "I have a hunch that I am correct". That typified his approach to physics. The work of 1959 demonstrated beyond all doubt that substantial coherence, manifested as strong beats in the intensity of the

Nutritional advice from George Orwell

DEFF Research Database (Denmark)

Larsen, Morten Hedegaard

2015-01-01

is historical descriptions (in the form of excerpts) from George Orwell's 1937 book “The Road to Wigan Pier” on the living conditions of the British working classes. These descriptions will be aligned with results from contemporary research into nutritional behaviour. Strong similarities are identified between...... George Orwell's historical descriptions of the working-class's unhealthy diet and the findings from contemporary research into nutritional behaviour of people with a low socio-economic status. The article, on this basis, argues that certain social mechanisms influencing nutritional choices are readily...... identifiable across disciplines, and even partly reproduced in different historical, social and spatial contexts, with stronger negative (ill health) consequences for people with low socio-economic status especially. Finally the article discusses how social mechanisms affecting our nutritional choices could...

Georg Cantor: habitar lo eterno

OpenAIRE

Penagos, Juan Manuel Rodríguez

2002-01-01

Este artículo pone en discusión la relación entre estructura psíquica y la producción lógica del delirio; para ello, parte de un matemático alemán llamado Georg Cantor. Aquí se discute la relación entre la producción matemática y la instalación de su psicosis. Este artigo coloca em discussão a relação entre estrutura psíquica e a produção lógica do delírio, partindo de um matemático alemão chamado Georg Cantor. Discutese ainda a relação entre a produção matemática e a instalação de sua psi...

Dodson, Prof. George Guy

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 2003 Honorary. Dodson, Prof. George Guy FRS. Date of birth: 13 January 1937. Date of death: 24 December 2012. Last known address: Division of Protein Structure, National Institute for Medical, Research, Mill Hill, London NW7 1AA, U.K.. YouTube; Twitter; Facebook; Blog ...

Safety and Feasibility of Lin- Cells Administration to ALS Patients: A Novel View on Humoral Factors and miRNA Profiles

Directory of Open Access Journals (Sweden)

Anna Sobuś

2018-04-01

Full Text Available Therapeutic options for amyotrophic lateral sclerosis (ALS are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF, brain-derived neurotrophic factor (BDNF, and vascular endothelial growth factor (VEGF and in the immune modulating features, in particular, the anti-inflammatory effects. In our study we aimed to investigate whether a bone marrow-derived lineage-negative (Lin- cells population, after autologous application into cerebrospinal fluid (CSF, is able to produce noticeable concentrations of trophic factors and inflammatory-related proteins and thus influence the clinical course of ALS. To our knowledge, the evaluation of Lin- cells transplantation for ALS treatment has not been previously reported. Early hematopoietic Lin- cells were isolated from twelve ALS patients’ bone marrow, and later, the suspension of cells was administered into the subarachnoid space by lumbar puncture. Concentrations of selected proteins in the CSF and plasma were quantified by multiplex fluorescent bead-based immunoassays at different timepoints post-transplantation. We also chose microRNAs (miRNAs related to muscle biology (miRNA-1, miRNA-133a, and miRNA-206 and angiogenesis and inflammation (miRNA-155 and miRNA-378 and tested, for the first time, their expression profiles in the CSF and plasma of ALS patients after Lin- cells transplantation. The injection of bone marrow cells resulted in decreased concentration of selected inflammatory proteins (C3 after Lin- cells injection, particularly in patients who had a better clinical outcome. Moreover, several analyzed miRNAs have changed expression levels in the CSF and plasma of ALS patients subsequent to Lin- cells administration. Interestingly, the expression of miR-206 increased in ALS patients, while miR-378 decreased both in the CSF and plasma one month after the cells’ injection. We propose that autologous lineage

Safety and Feasibility of Lin- Cells Administration to ALS Patients: A Novel View on Humoral Factors and miRNA Profiles.

Science.gov (United States)

Sobuś, Anna; Baumert, Bartłomiej; Litwińska, Zofia; Gołąb-Janowska, Monika; Stępniewski, Jacek; Kotowski, Maciej; Pius-Sadowska, Ewa; Kawa, Miłosz P; Gródecka-Szwajkiewicz, Dorota; Peregud-Pogorzelski, Jarosław; Dulak, Józef; Nowacki, Przemysław; Machaliński, Bogusław

2018-04-27

Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular endothelial growth factor (VEGF)) and in the immune modulating features, in particular, the anti-inflammatory effects. In our study we aimed to investigate whether a bone marrow-derived lineage-negative (Lin-) cells population, after autologous application into cerebrospinal fluid (CSF), is able to produce noticeable concentrations of trophic factors and inflammatory-related proteins and thus influence the clinical course of ALS. To our knowledge, the evaluation of Lin- cells transplantation for ALS treatment has not been previously reported. Early hematopoietic Lin- cells were isolated from twelve ALS patients’ bone marrow, and later, the suspension of cells was administered into the subarachnoid space by lumbar puncture. Concentrations of selected proteins in the CSF and plasma were quantified by multiplex fluorescent bead-based immunoassays at different timepoints post-transplantation. We also chose microRNAs (miRNAs) related to muscle biology (miRNA-1, miRNA-133a, and miRNA-206) and angiogenesis and inflammation (miRNA-155 and miRNA-378) and tested, for the first time, their expression profiles in the CSF and plasma of ALS patients after Lin- cells transplantation. The injection of bone marrow cells resulted in decreased concentration of selected inflammatory proteins (C3) after Lin- cells injection, particularly in patients who had a better clinical outcome. Moreover, several analyzed miRNAs have changed expression levels in the CSF and plasma of ALS patients subsequent to Lin- cells administration. Interestingly, the expression of miR-206 increased in ALS patients, while miR-378 decreased both in the CSF and plasma one month after the cells’ injection. We propose that autologous lineage-negative early

The 1995 Georges Bank Stratification Study and Moored Array Measurements

National Research Council Canada - National Science Library

Alessi, C

2001-01-01

.... GLOBEC Northwest Atlantic/Georges Bank field program. The GBSS was designed to investigate the physical processes which control the seasonal development of stratification along the southern flank of Georges Bank during spring and summer...

George Sandi "Consuelo" / Ott Ojamaa

Index Scriptorium Estoniae

Ojamaa, Ott, 1926-1996

2010-01-01

Arvustus: Sand, George, pseud. Consuelo. 1-2. : romaan / [prantsuse keelest tõlkinud Leili-Maria Kask järelsõna ja märkused: Ott Ojamaa]. Tallinn : Eesti Riiklik Kirjastus, 1961. (Suuri sõnameistreid). 2. tr. ilmus 1988. a.

George Sigerson: Charcot's translator.

Science.gov (United States)

Lyons, J B

1997-04-01

Senator George Sigerson (1836-1925), Dublin's first neurologist, was also a significant contributor to Anglo-Irish literature. His medical career and literary accomplishments are outlined, the focus of the article being Sigerson's friendly relationship with Charcot (with whom he corresponded), and whose Leçons sur les maladies du système nerveux he translated.

Who Framed George Lakoff?

Science.gov (United States)

Goldstein, Evan R.

2008-01-01

In this article, a noted linguist reflects on his tumultuous foray into politics. For years George P. Lakoff has been at the center of some of the biggest intellectual disagreements in linguistics (most famously with Noam Chomsky) and has helped create an important interdisciplinary field of study, cognitive linguistics, that is reshaping people's…

Series, Prof. George William

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Series, Prof. George William. Date of birth: 22 February 1920. Date of death: 2 January 1995. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

77 FR 1716 - James River National Wildlife Refuge, Prince George County, VA

Science.gov (United States)

2012-01-11

... River National Wildlife Refuge, Prince George County, VA AGENCY: Fish and Wildlife Service, Interior... (the refuge, NWR), which is located in Prince George County, Virginia. We provide this notice in... River NWR, in Prince George County, Virginia. This notice complies with our CCP policy to advise other...

George and the blue moon

CERN Document Server

Hawking, Lucy

2016-01-01

George and his best friend, Annie have been selected as junior astronauts - part of a programme that trains up young people for a trip to Mars in the future. This is everything they've ever wanted - they get to be a part of up-to-the minute space discoveries and meet a bunch of new friends who are as fascinated by the universe as they are. But when they arrive at space camp, George and Annie quickly learn that strange things are happening - on Earth as well as up in our skies. Mysterious space missions are happening in secret, and the astronaut training they're undertaking gets scarier and scarier . . . The fifth adventure in this series by Lucy and Stephen Hawking - also containing up-to-the-minute scientific facts and information by the world's leading scientists.

Lin28a is a putative factor in regulating cancer stem cell-like properties in side population cells of oral squamous cell carcinoma

Energy Technology Data Exchange (ETDEWEB)

Hayashi, S.; Tanaka, J.; Okada, S.; Isobe, T.; Yamamoto, G.; Yasuhara, R.; Irie, T.; Akiyama, C.; Kohno, Y.; Tachikawa, T.; Mishima, K., E-mail: mishima-k@dent.showa-u.ac.jp

2013-05-01

Cancer stem cells (CSCs) are among the target cells of cancer therapy because they are uniquely involved in both cancer progression and sensitivity to chemotherapeutic agents. We identified side population (SP) cells, which are known to be an enriched population of CSC, in five oral squamous cell carcinoma (OSCC) cells (SCC9, SCC25, TOSCC7, TOSCC17, and TOSCC23). The percentages of SP cells ranged from 0% to 3.3%, with TOSCC23 cells showing the highest percentages of SP cells (3.3% of the total cell population). The SP cells isolated from TOSCC23 cells also showed greater cell proliferation and invasion compared to non-SP (MP) cells. Therefore, our initial findings suggested that SP cells were enriched for CSC-like cells. Furthermore, DNA microarray analysis revealed that the expression of cell proliferation-related and anti-apoptotic genes was greater in SP cells compared to MP cells. We focused on Lin28a, which showed the highest expression (approximately 22-fold) among the upregulated genes. The overexpression of Lin28a in TOSCC23 cells increased their proliferation, colony formation, and invasion. These findings suggest that Lin28a is an appropriate CSC target molecule for OSCC treatment - Highlights: ► Lin28a is a SP cell-specific factor in oral squamous cell carcinoma (OSCC) cells. ► SP cells in OSCC cells show cancer stem cell-like properties. ► Lin28a regulates OSCC proliferative and invasive activities.

Lin28a is a putative factor in regulating cancer stem cell-like properties in side population cells of oral squamous cell carcinoma

International Nuclear Information System (INIS)

Hayashi, S.; Tanaka, J.; Okada, S.; Isobe, T.; Yamamoto, G.; Yasuhara, R.; Irie, T.; Akiyama, C.; Kohno, Y.; Tachikawa, T.; Mishima, K.

2013-01-01

Cancer stem cells (CSCs) are among the target cells of cancer therapy because they are uniquely involved in both cancer progression and sensitivity to chemotherapeutic agents. We identified side population (SP) cells, which are known to be an enriched population of CSC, in five oral squamous cell carcinoma (OSCC) cells (SCC9, SCC25, TOSCC7, TOSCC17, and TOSCC23). The percentages of SP cells ranged from 0% to 3.3%, with TOSCC23 cells showing the highest percentages of SP cells (3.3% of the total cell population). The SP cells isolated from TOSCC23 cells also showed greater cell proliferation and invasion compared to non-SP (MP) cells. Therefore, our initial findings suggested that SP cells were enriched for CSC-like cells. Furthermore, DNA microarray analysis revealed that the expression of cell proliferation-related and anti-apoptotic genes was greater in SP cells compared to MP cells. We focused on Lin28a, which showed the highest expression (approximately 22-fold) among the upregulated genes. The overexpression of Lin28a in TOSCC23 cells increased their proliferation, colony formation, and invasion. These findings suggest that Lin28a is an appropriate CSC target molecule for OSCC treatment - Highlights: ► Lin28a is a SP cell-specific factor in oral squamous cell carcinoma (OSCC) cells. ► SP cells in OSCC cells show cancer stem cell-like properties. ► Lin28a regulates OSCC proliferative and invasive activities

Georges et les trésors du cosmos

CERN Document Server

Hawking, Lucy; Parsons, Gary

2011-01-01

Les voisins excentriques de Georges, Annie et Eric, ont déménagé en Floride à l'agence Spatiale Globale. Là-bas, Eric s'occupe de son nouveau robot, Homer, qui doit détécter les signes de vie sur Mars. Mais bientôt, Georges reçoit un e-mail : Annie lui demande de la rejoindre au plus vite pour une " mission cosmique " secrète. La jeune fille est persuadée qu'il se passe de drôles de choses sur Mars, car Homer vient de recevoir un message extraterrestre ! Georges et Anne (avec l'aide d'Emmett, un petit garçon bizarre) décident de réparer Cosmos, leur super-ordinateur, et d'aller voir par eux-mêmes... Emmaillotés dans des combinaisons spéciales, ils se lancent alors dans une fabuleuse chasse aux trésors sur Mars, sur les lunes de Saturne, puis sur Titan, avant de se perdre en orbite autour d'Alpha Centauri B... Mais avant de pouvoir élucider le mystère du message extraterrestre, Georges et Annie devront se livrer à une bataille spatiale acharnée qui mettra leur vie en danger, ainsi que ce...

George Mikenberg honoured by the Sharing Knowledge Foundation

CERN Multimedia

CERN Bulletin

2016-01-01

The Sharing Knowledge Foundation Prize was presented to the ATLAS physicist at a ceremony on 18 March.   ATLAS physicist George Mikenberg receives the Sharing Knowledge Foundation Prize. From left to right: Peter Jenni, former ATLAS Spokesperson, Rolf Heuer, former CERN Director-General, Frédérick Bordry, CERN Director for Accelerators and Technology, George Mikenberg, Patrick Fassnacht, CERN International Relations sector, Eliane Jacot-Des-Combes Mikenberg, Herwig Schopper, former CERN Director-General, Constantin Lanaras, treasurer of the Sharing Knowledge Foundation, Robert Klapisch, President of the Sharing Knowledge Foundation, Federico Saldana, logistical support, Catherine Cesarsky, Vice-President of the CERN Council, Eliezer Rabinovici, Vice-President of the CERN Council and of SESAME. (Image: Sophia Bennett/CERN) The Sharing Knowledge Foundation awarded its 2016 prize to George Mikenberg, a member of the LHC's ATLAS experiment who has been...

Long noncoding RNA TUG1 facilitates osteogenic differentiation of periodontal ligament stem cells via interacting with Lin28A.

Science.gov (United States)

He, Qin; Yang, Shuangyan; Gu, Xiuge; Li, Mengying; Wang, Chunling; Wei, Fulan

2018-04-19

Periodontal ligament stem cells (PDLSCs) are mesenchymal stem cells derived from dental tissues with multidirectional differentiation potential and excellent self-renewing ability. Recently, long noncoding RNAs (lncRNAs) have been shown to play important roles in MSC osteogenic differentiation. In this study, we found that taurine upregulated gene 1 (TUG1), an evolutionarily conserved and widely present lncRNA was significantly upregulated in osteogenically induced PDLSCs compared to their undifferentiated counterparts. Further investigation demonstrated that the expression of TUG1 was positively correlated with the osteogenic differentiation of PDLSCs following the induction, as evidenced by the increase in cellular alkaline phosphatase (ALP) level, formation of calcium nodules, and the upregulation of several osteogenic-related gene markers such as ALP, osteocalcin (OCN), and runt-related transcription factor 2 (Runx2). Conversely, TUG1 knockdown was demonstrated to inhibit the potential of PDLSCs for osteogenic differentiation. Using bioinformatics analysis, we identified lin-28 homolog A (Lin28A) as a potential target of TUG1 during osteogenic differentiation of PDLSCs. Lin28A was found to be significantly downregulated in TUG1-repressed PDLSCs and contained multiple binding sites for lncRNA TUG1. Moreover, suppression of Lin28A was shown to be able to inhibit osteogenic differentiation and decreased the expression of several osteogenic genes. Taken together, these results could help researchers better understand the mechanism that governs the osteogenic differentiation of PDLSCs, and also serve as a stepping stone for the development of novel therapeutic strategies that can be used to regenerate dental tissues.

Georges Didi-Huberman, Images malgré tout

OpenAIRE

Shafto, Sally

2008-01-01

« Pour savoir, il faut s’imaginer. »Georges Didi-Huberman Avec son dernier livre, Images malgré tout, l’historien de l’art et philosophe Georges Didi-Huberman nous livre un texte élégamment écrit et divisé en trois mouvements. Il y a d’abord une réimpression de son article, paru auparavant dans le catalogue, Mémoires des camps. Photographies des camps de concentration et d’extermination nazis 1933-1999. Il s’agit d’une lecture phénoménologique de quatre photographies, prises à Auschwitz en ao...

Johann Georg Eisen / Indrek Jürjo

Index Scriptorium Estoniae

Jürjo, Indrek, 1956-2009

1999-01-01

Rets. rmt.: Johann Georg Eisen (1717-1779). Ausgewählte Schriften. Deutsche Volksaufklärung und Leibeigenschaft im Russischen Reich. Hrsg. von Roger Bartlett und Erich Donnert. Marburg : IHerder-Institut, 1998

Let Slip the Dogs of (CYBER) War: Progressing Towards a Warfighting U.S. Cyber Command

Science.gov (United States)

2013-04-01

requirements, nor a headquarters building (it is currently housed within NSA facilities on Fort George G. Meade , MD).22 In addition, the DOD cyber...Information Conflict: National Security Law in Cyberspace (Falls Church, VA: Aegis Research Corporation, 2000); Herbert Lin, “Offensive Cyber Operations...this legislation was pocket-vetoed by then President George H.W. Bush due to a lack of consistency between the stated intent of the oversight

75 FR 21243 - Marine Mammals; Subsistence Taking of Northern Fur Seals; St. George

Science.gov (United States)

2010-04-23

... Mammals; Subsistence Taking of Northern Fur Seals; St. George AGENCY: National Marine Fisheries Service... (APA). The Pribilof Island Community of St. George Island, Traditional Council (Council) petitioned... St. George Island to take male fur seal young of the year during the fall. NMFS solicits public...

George de Hevesy

International Nuclear Information System (INIS)

Levi, H.

1985-01-01

George de Hevesy (1875-1966) worked with Rutherford in Manchester in the early 1900's and with Niels Bohr in Denmark after the first world war. With Coster he discovered an unknown element, later named Hafrivm. In the 1930's he moved to Copenhagen and developed radiotracer techniques using the new artificially produced radioisotopes. This work found wide application in medicine and biology and other branches of science and technology and for his pioneer work de Hevesy was awarded a Nobel Prize in 1944. (UK)

Tip 2 Diabetes Mellituslu Hastalarda Mikroalbuminüri, İnsülin Direnci ve Kardiyovasküler Risk

OpenAIRE

ERSOY, Canan; TAŞLI, Babürşah; YILDIZ, Abdülmecit; İMAMOĞLU, Şazi

2006-01-01

Son çalışmalar tip 2 diyabette mikroalbuminüri (MAU) varlığı ile hedef organ hasarları ve kardiyovasküler hastalık riski arasındaki ilişkilere yönelmişlerdir. Bu çalışmada, Tip 2 diabetes mellituslu (DM) hastalarda MAU ile glisemik kontrol, insülin direnci (İR) ve diğer kardiyovasküler risk faktörleri arasındaki ilişki değerlendirilmiştir. İnsülin gereksinimi olmayan, normal renal fonksiyonlu 29 mikroalbuminürik ve 68 normoalbuminürik tip 2 DM'lu hasta çalışmaya dahil edildi. Tüm hast...

Properties of the fullerene C_6_0-containing PN Lin49 in the SMC; Explanations of strong near-IR excess

International Nuclear Information System (INIS)

Otsuka, Masaaki; Kemper, Francisca; Leal-Ferreira, Marcelo L.; Aleman, Isabel; Ochsendorf, Bram; Bernard-Salas, Jeronimo; Cami, Jan; Peeters, Els

2016-01-01

We performed a detailed spectroscopic analysis of the fullerene C_6o-containing planetary nebula (PN) Lin49 in the Small Magellanic Cloud (SMC). Lin49 is a C-rich and metal- deficient PN (Z∼⃒0.0006) and its nebular abundances are in agreement with the AGB model for the initially 1.25M_☉ stars with the metallicity Z = 0.001 of Fishlock et al. (2014, [1]). By stellar absorption fitting with TLUSTY, we derived stellar abundances, effective temperature, and surface gravity. We constructed the photo-ionization model with CLOUDY in order to investigate physical conditions of Lin49. The model with the 0.005-0.1 μm radius graphite and a constant hydrogen density shell could not fit the ∼⃒1-5 μm SED owing to the strong near-IR excess. We propose that the near-IR excess indicates (1) the presence of extremely small carbon molecules or (2) the presence of high-density structure surrounding the central star. (paper)

Crystal structures of MW1337R and lin2004: Representatives of a novel protein family that adopt a four-helical bundle fold

Energy Technology Data Exchange (ETDEWEB)

Kozbial, Piotr; Xu, Qingping; Chiu, Hsiu-Ju; McMullan, Daniel; Krishna, S. Sri; Miller, Mitchell D.; Abdubek, Polat; Acosta, Claire; Astakhova, Tamara; Axelrod, Herbert L.; Carlton, Dennis; Clayton, Thomas; Deller, Marc; Duan, Lian; Elias, Ylva; Elsliger, Marc-André; Feuerhelm, Julie; Grzechnik, Slawomir K.; Hale, Joanna; Han, Gye Won; Jaroszewski, Lukasz; Jin, Kevin K.; Klock, Heath E.; Knuth, Mark W.; Koesema, Eric; Kumar, Abhinav; Marciano, David; Morse, Andrew T.; Murphy, Kevin D.; Nigoghossian, Edward; Okach, Linda; Oommachen, Silvya; Reyes, Ron; Rife, Christopher L.; Spraggon, Glen; Trout, Christina V.; ban den Bedem, Henry; Weekes, Dana; White, Aprilfawn; Wolf, Guenter; Zubieta, Chloe; Hodgson, Keith O.; Wooley, John; Deacon, Ashley M.; Godzik, Adam; Lesley, Scott A.; Wilson, Ian A. (Scripps); (SSRL); (JCSG); (UCSD); (Burnham)

2009-08-28

To extend the structural coverage of proteins with unknown functions, we targeted a novel protein family (Pfam accession number PF08807, DUF1798) for which we proposed and determined the structures of two representative members. The MW1337R gene of Staphylococcus aureus subsp. aureus Rosenbach (Wood 46) encodes a protein with a molecular weight of 13.8 kDa (residues 1-116) and a calculated isoelectric point of 5.15. The lin2004 gene of the nonspore-forming bacterium Listeria innocua Clip11262 encodes a protein with a molecular weight of 14.6 kDa (residues 1-121) and a calculated isoelectric point of 5.45. MW1337R and lin2004, as well as their homologs, which, so far, have been found only in Bacillus, Staphylococcus, Listeria, and related genera (Geobacillus, Exiguobacterium, and Oceanobacillus), have unknown functions and are annotated as hypothetical proteins. The genomic contexts of MW1337R and lin2004 are similar and conserved in related species. In prokaryotic genomes, most often, functionally interacting proteins are coded by genes, which are colocated in conserved operons. Proteins from the same operon as MW1337R and lin2004 either have unknown functions (i.e., belong to DUF1273, Pfam accession number PF06908) or are similar to ypsB from Bacillus subtilis. The function of ypsB is unclear, although it has a strong similarity to the N-terminal region of DivIVA, which was characterized as a bifunctional protein with distinct roles during vegetative growth and sporulation. In addition, members of the DUF1273 family display distant sequence similarity with the DprA/Smf protein, which acts downstream of the DNA uptake machinery, possibly in conjunction with RecA. The RecA activities in Bacillus subtilis are modulated by RecU Holliday-junction resolvase. In all analyzed cases, the gene coding for RecU is in the vicinity of MW1337R, lin2004, or their orthologs, but on a different operon located in the complementary DNA strand. Here, we report the crystal structures

Obituary: George Hamilton Bowen Jr. (1925-2009)

Science.gov (United States)

Willson, Lee Anne; Struck, Curtis

2011-12-01

Our colleague and collaborator George Hamilton Bowen, Jr., passed away November 1, 2009 in Ames, Iowa. George was born June 20, 1925 in Tulsa, Oklahoma to George and Dorothy (Huntington) Bowen. He married Marjorie Brown June 19, 1948 in Redondo Beach, California; they had five children, with eight grandchildren and five great-grandchildren at the time of his death. George H. Bowen's third or perhaps his fourth career was in astronomy. He was drafted into the navy in 1944, at the end of his first year as a student at Caltech, and ended his war-time service as an electronic technician on the aircraft carrier Shangri-La. He later said "In just nine months, starting from scratch (Ohm's law!), we learned an amazing amount - not by memorization, of course, but by study and real understanding of the basic function of the most advanced AC circuits then being used for instrumentation, measurements, communications, control systems, and much more." He gained a confidence that he could quickly and accurately diagnose and solve technical problems that stood him well in future work. One accomplishment he took particular pride in was figuring out how the radar control used cams and gears to solve the trigonometry for accurate pointing. He also described how the captain was alarmed when weather conditions changed so that refraction no longer showed them distant, small boats around the curvature of Earth. After the war, George Bowen returned to undergraduate and eventually graduate study at Caltech, where he was recruited to the biophysics research group headed by future Nobel Laureate Max Delbrück. George often described his joy in working with these first-rate scientists and finding himself accepted as a part of the effort. He finished his BS with honors in 1949 and his PhD in 1953 with a thesis on "Kinetic Studies on the Mechanism of Photoreactivation of Bacteriophase T2 Inactivated by Ultraviolet Light" involving work with E Coli. This work was supported by grants from the U

George Hoyt Whipple and the Impact of Liver on Anemia

Science.gov (United States)

dropdown arrow Site Map A-Z Index Menu Synopsis George Hoyt Whipple and the Impact of Liver on Anemia cases of anemia". George Hoyt Whipple Courtesy of University of Rochester Medical Center Whipple's main research was concerned with anemia and with the physiology and pathology of the liver. He won the

George Sand: últimas novelas, últimos ensueños...

Directory of Open Access Journals (Sweden)

Àngels Santa

2014-04-01

Full Text Available A propósito de la obra de George Sand, Œuvres complètes.Sous la direction de Béatrice Didier. 1870, I :Malgrétout. Édition critique par Dominique Laporte (París, Honoré Champion, 2013, 247 p. ISBN : 9782745322968 y de George Sand, Œuvres complètes.Sous la direction de Béatrice Didier. 1876 :La Tour de Percemont. Édition critique par Dominique Laporte (París, Honoré Champion, 2013, 247 p. ISBN : 9782745322951.

George Morrison: Anishinaabe Expressionist Artist

Science.gov (United States)

Vizenor, Gerald

2006-01-01

In this article, the author discusses the life and works of an Anishinaabe expressionist artist George Morrison. Morrison was an eminent expressionist painter with a singular romantic vision and an erudite sense of natural reason and liberty. He created an elusive shimmer of "endless space," the color and eternal motion of nature. The…

The Georg Jensen and Alessi Design

DEFF Research Database (Denmark)

Tanderup, Sisse

2009-01-01

in the design process. Alessi's motivation for involving the concept of memory is that it adds a cultural dimension to the design objects, enabling the objects to make an identity-forming impact. Compared to this, Danish and Scandinavian design practice has traditionally focused on form and function......  The Georg Jensen and Alessi Design A comparative analysis focusing on the use of memory   The dimension of memory has become a central theme within several fields of research, including architecture, philosophy, psychology and medicine. However, memory has not yet been explored more substantially...... as an independent identity category in design research. This article deals with the use of the memory theme in design examples from the two companies Georg Jensen and Alessi. Italian design practice is characterized by a tradition of involving memory categories from Italian history, philosophy, art and tradition...

José Lins do Rego: um guia brasileiro de Israel

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Glauber Pereira Quintão

2010-03-01

Full Text Available Este artigo procura analisar, de forma crítica, o livro de José Lins do Rego, Roteiro de Israel, 1955. Busca-­se destacar duas facetas suplementares: a de um olhar poético e a de uma preocupação ético-política lançados pelo escritor sobre a construção do novo Estado de Israel. Observa-­se também uma relação entre os signos da modernidade e das histórias arcaica judaicas. Para isso, usa-­se o conceito de palimpsesto, de Gerard Genette, e de flâneur, de Walter Benjamim.

Master Mentors: Linda Golian-Lui University of Hawaii-Hilo--George Oberle George Mason University, VA

Science.gov (United States)

Library Journal, 2005

2005-01-01

Many movers and shakers inspire admiration and even awe, but those who inspire love are the mentors who have changed lives. That is why many grateful librarians nominated Linda Golian-Lui and George Oberle. Both of them were accidental librarians, work-study students whose supervisors encouraged them to become paraprofessionals, and then…

Synthèse et validation d'une loi de commande linéaire robuste de braquage d'une automobile

OpenAIRE

MENHOUR, Lghani; LECHNER, Daniel; CHARARA, Ali

2010-01-01

Ce papier propose la synthèse d'un retour d'état robuste préprogrammé pour le contrôle de direction d'un véhicule. Celui-ci est utilisé pour simuler le comportement du véhicule sous des fortes sollicitations dynamiques. Les contraintes d'inégalités matricielles linéaires (LMI) et un modèle linéaire à paramètres variants sont utilisés pour la synthèse du retour d'état. Ensuite, une méthode d'interpolation des gains est utilisée pour la conception d'un retour d'état robuste préprogrammé. La str...

Functional study of risk loci of stem cell-associated gene lin-28B and associations with disease survival outcomes in epithelial ovarian cancer.

Science.gov (United States)

Lu, Lingeng; Katsaros, Dionyssios; Mayne, Susan T; Risch, Harvey A; Benedetto, Chiara; Canuto, Emilie Marion; Yu, Herbert

2012-11-01

Several single-nucleotide polymorphisms (SNPs) of the stem cell-associated gene lin-28B have been identified in association with ovarian cancer and ovarian cancer-related risk factors. However, whether these SNPs are functional or might be potential biomarkers for ovarian cancer prognosis remains unknown. The purposes of this study were to investigate the functional relevance of the identified lin-28B SNPs, as well as the associations of genotype and phenotype with epithelial ovarian cancer (EOC) survival. We analyzed five SNPs and mRNA levels of lin-28B in 211 primary EOC tissues using Taqman(®) SNP genotyping assays and SYBR green-based real-time PCR, respectively. The RNA secondary structures at the region of a genome-wide association-identified intronic rs314276 were analyzed theoretically with mfold and experimentally with circular dichroism spectroscopy. We found that rs314276 was a cis-acting expression quantitative trait locus (eQTL) in both additive and dominant models, while rs7759938 and rs314277 were significant or of borderline significance in dominant models only. The rs314276 variant significantly affects RNA secondary structure. No SNPs alone were associated with patient survival. However, we found that among patients initially responding to chemotherapy, those with higher lin-28B expression had higher mortality risk (hazard ratio =3.27, 95% confidence interval: 1.63-6.56) and relapse risk (hazard ratio = 2.53, 95% confidence interval: 1.41-4.54) than those with lower expression, and these associations remained in multivariate analyses. These results suggest that rs314276 alters RNA secondary structure and thereby influences gene expression, and that lin-28B is a cancer stem cell-associated marker, which may be a pharmaceutical target in the management of EOC.

Kdo byl Georg Placzek (1905-1955)

Czech Academy of Sciences Publication Activity Database

Gottvald, Aleš

2005-01-01

Roč. 55, č. 3 (2005), s. 275-287 ISSN 0009-0700 Institutional research plan: CEZ:AV0Z20650511 Keywords : Georg Placzek * the oretical physics * history of physics * nuclear physics * Manhattan project * spectroscopy Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

Haldusreformist üldiselt / Georg Sootla, Kersten Kattai

Index Scriptorium Estoniae

Sootla, Georg, 1954-

2016-01-01

Haldusreformi ning Pärnu linna ja Are, Audru, Paikuse ja Tõstamaa valla ühinemise kohta jagavad selgitusi ühinemise konsultandid, Tallinna Ülikooli professor Georg Sootla ja lektor Kersten Kattai

LEDWIRE: A Versatile Networking Platform for Smart LED Lighting Applications Using LIN-Bus and WSNs

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Dimitrios D. Piromalis

2016-05-01

Full Text Available In this paper, the architecture of a versatile networking and control platform for Light-Emitting Diode (LED lighting applications is presented, based on embedded wireless and wired networking technologies. All the possible power and control signals distribution topologies of the lighting fixtures are examined with particular focus on dynamic lighting applications with design metrics as the cost, the required wiring installation expenses and maintenance complexity. The proposed platform is optimized for applications where the grouping of LED-based lighting fictures clusters is essential, as well as their synchronization. With such an approach, the distributed control and synchronization of LED lighting fixtures' clusters is performed through a versatile network that uses the single wire Local Interconnect Network (LIN bus. The proposed networking platform is presented in terms of its physical layer architecture, its data protocol configuration, and its functionality for smart control. As a proof of concept, the design of a LED lighting fixture together with a LIN-to-IEEE802.15.4/ZigBee data gateway is presented.

Moessbauer Study of Sedimentary Rocks from King George Island, Antarctica

International Nuclear Information System (INIS)

Kuzmann, E.; Souza, P. A. de; Schuch, L. A.; Oliveira, A. C. de; Garg, R.; Garg, V. K.

2002-01-01

The separation of continents at the periphery of Antarctica occurred about 180 ma ago due to volcanic activity. Geological faults can be very important in the study of geological occurrences. Such geological faults occur across the Admiralty Bay, King George Island, and have been studied in detail previously. Controversial statements were given in earlier works, based on conventional geological investigations, as to whether altered 'Jurassic' and unaltered Tertiary rocks were separated by a major fault which goes across the Admiralty Bay, or whether there is no difference in the alteration of the rocks located at either side of the fault. The aim of our work is to investigate rock samples from the Admiralty Bay of King George Island, Antarctica, from different locations on both sides of the geological fault. For these investigations 57 Fe Moessbauer spectroscopy and X-ray diffractometry were used. We have found that the phase composition, and the iron distribution among the crystallographic sites of iron-bearing minerals, are characteristic of the location of the rock samples from the Admiralty Bay of King George Island. There is a much higher amount of iron oxides in the rocks from the south part of the geological fault than in the north part. The differences in the mineral composition and iron distribution showed that the rocks in the southern part of the geological fault of King George Island are significantly altered compared to the rocks in the northern part. Our present results support and complement well the results obtained earlier on soils from King George Island.

Analyzing Street Art to Present the Heritage of George Town, Malaysia

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Seyedehelham Sadatiseyedmahalleh

2015-08-01

Full Text Available Street art comprises all kinds of art developed in public locations. This form of art has spread to all heritage streets in George Town, the capital of Penang Island, which is also a known UNESCO World Heritage Site. However, instead of its heritage, food, and interesting past life and structure, the rapid multiplication of street art in George Town has created a new and unusual art that attracts tourists. Street art has spread to small roads and heritage streets in the city. This art increases the awareness of spectators by introducing them to the rich history of these streets and inducing a lively concept in the inner city of George Town. Accordingly, the impact of iron rod sculptures and murals, which comprises approximately 90% of street art in George Town, were determined to explore and identify the effects of this street art on this world heritage site. The findings were obtained from 263 out of 306 questionnaires accomplished by tourists in George Town. The results confirm that tourists prefer murals over iron rod sculptures. Iron rod sculptures are designed to tell the history of the street, whereas murals are designed to create aesthetic value. The findings indicated that similar to iron rod sculptures, more control should be exercised on the subjects of murals.

An Adaptation of the Kernighan-Lin Heuristic to the Simple Graph Partitioning Problem

DEFF Research Database (Denmark)

Sørensen, Michael Malmros

1999-01-01

to this problem of the Kernighan-Lin exchange heuristic, which was originally developed for the closely related 2-partition problem. The evaluation is carried out on problem instances on graphs with up to 50 nodes for which the optimal partition values are known or upper bounds are available. The computational...... results show that among all instances with known optimal values the best partition values found by a randomized version of this heuristic lie well within 1% off the optimum....

Georges et les secrets de l'univers

CERN Document Server

Hawking, Lucy; Galfard, Christophe; Parsons, Gary

2011-01-01

Un voyage ex-tra-or-di-naire dans l'Univers! Le jour où Georges rencontre ses nouveaux voisins, il est loin d'imaginer que sa vision du monde va être totalement bouleversée. Chez la jeune Annie et Éric, son scientifique de père, le garçon découvre Cosmos, l'ordinateur le plus perfectionné qui soit. Sa super intelligence permet de protéger Georges et ses amis aux quatre coins de l'Univers ! Hélas, quelqu'un nourrit de sombres projets... et quand on sait qu'il n y a rien de plus dangereux dans l'espace qu'un trou noir, il y a du souci à se faire ! Un roman essentiel sur l'Univers avec les découvertes de Stephen Hawking.

George W. Bushi "intellektuaalne armuromaan" / Urmas Kiil

Index Scriptorium Estoniae

Kiil, Urmas

2005-01-01

Paljude poliitikute arvates kinnitab USA presidendi George Bushi vaimustus Natan Sharanski raamatust "The Case of Democracy: The Power of Freedom to Overcome Tyranny and Terror " fakti, et midagi pole tema poliitikas muutunud ka teisel ametiajal

Georges Darrieus, inventor of vertical axis wind-turbines; Georges Darrieus, pere des eoliennes a axe vertical

Energy Technology Data Exchange (ETDEWEB)

Rogier, E.

2000-10-01

This article is a short biography of the French man Georges Darrieus (1888-1979) who invented the vertical wind turbine. G.Darrieus can be considered as the first industrial researcher in France, he was a double authority in sciences and in industry machinery. He presented more than 50 patterns and wrote about 700 scientific and technological articles.

Georg Cantor: habitar lo eterno

Directory of Open Access Journals (Sweden)

Juan Manuel Rodríguez Penagos

Full Text Available Este artículo pone en discusión la relación entre estructura psíquica y la producción lógica del delirio; para ello, parte de un matemático alemán llamado Georg Cantor. Aquí se discute la relación entre la producción matemática y la instalación de su psicosis.

Noonan's and DiGeorge syndromes with monosomy 22q11.

OpenAIRE

Wilson, D I; Britton, S B; McKeown, C; Kelly, D; Cross, I E; Strobel, S; Scambler, P J

1993-01-01

A boy with the dysmorphic features of Noonan's syndrome and pulmonary valve stenosis who had evidence of hypoparathyroidism and abnormal T lymphocyte numbers in the neonatal period is reported. He had a normal karyotype but molecular analysis revealed a submicroscopic deletion within chromosome 22q11, the region deleted in DiGeorge syndrome. Thus this child has both Noonan's syndrome and DiGeorge syndrome; 22q11 is a candidate region for a gene defective in Noonan's syndrome.

U.S. GLOBEC Georges Bank Long-Term Moored Program. Part 1. Mooring Configuration

National Research Council Canada - National Science Library

Irish, J. D; Kerry, S; Fucile, P; Beardsley, R. C; Lord, J; Brink, K. H

2005-01-01

As part of the U.S. GLOBEC Northwest Atlantic/Georges Bank program, moorings were deployed on Georges Bank as part of the broad-scale survey component to help measure the temporal variability of both physical...

Lin28a Is Dormant, Functional, and Dispensable During Mouse Oocyte-to-Embryo Transition

Czech Academy of Sciences Publication Activity Database

Flemr, Matyáš; Moravec, Martin; Libová, Veronika; Sedláček, Radislav; Svoboda, Petr

2014-01-01

Roč. 90, č. 6 (2014), s. 1-9 ISSN 0006-3363 R&D Projects: GA MŠk LH13084; GA MŠk(CZ) LM2011032; GA ČR(CZ) GBP305/12/G034 Institutional support: RVO:68378050 Keywords : early development * genome activation * guinea pigs * Let-7 * LIN28 * mice * microRNA * oocyte * rats * RNAi * rodents * transgenic/ knockout model * voles * zygote Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.318, year: 2014

Georges Didi-Huberman

OpenAIRE

Hagelstein, Maud

2012-01-01

Georges Didi-Huberman est un philosophe et un historien de l'art français né à Saint-Étienne le 13 juin 1953. Il a été pensionnaire à l'Académie de France à Rome (Villa Médicis) et résident à la Fondation Berenson de la Villa I Tatti à Florence. Il enseigne à l’École des hautes études en sciences sociales où il est maître de conférences depuis 1990. Bibliographie Invention de l’hystérie. Charcot et l’Iconographie photographique de la Salpêtrière, sur l'École de la Salpêtrière, Macula, 1982. M...

George Bush peab sõjalist jõudu viimaseks valikuks / George W. Bush ; interv. Kaarel Kaas

Index Scriptorium Estoniae

Bush, George W., 1946-

2005-01-01

Ilmunud ka: Põhjarannik 7. mai 2005, lk. 2, Severnoje Poberezhje 7. mai, 2005, lk. 2. USA president George Bush andis 5. mail Valges Majas intervjuu kuuele Euroopa ajakirjanikule. 9. mai pidustustest Moskvas, USA-Läti, Venemaa-Balti riikide suhetest, demokraatiast Venemaal, Ameerika Ühendriikide ning Baltimaade viisarežiimist, vabaduse mõistestst, kinnipeetavate kohtlemisest Guantanamo sõjaväebaasis, relvade kasutamise vajadusest, terrorismist. Vt. samas: Kuidas usutlus võimalikuks sai

Optical and electrical properties of zinc oxide thin films with low resistivity via Li-N dual-acceptor doping

Energy Technology Data Exchange (ETDEWEB)

Zhang Daoli, E-mail: zhang_daoli@mail.hust.edu.cn [Department of Electronic Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China); Wuhan National Laboratory for Optoelectronics, 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China); Zhang Jianbing [Department of Electronic Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China); Wuhan National Laboratory for Optoelectronics, 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China); Guo Zhe [Department of Electronic Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China); Miao Xiangshui [Department of Electronic Science and Technology, Huazhong University of Science and Technology, No. 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China); Wuhan National Laboratory for Optoelectronics, 1037 Luoyu Road, Hongshan District, Wuhan City, Hubei Province 430074 (China)

2011-05-19

Highlights: > Zinc oxide films have been deposited on glass substrates by Li-N dual-acceptor doping method via a modified SILAR method. > The resistivity of ZnO film was found to be 1.04 {Omega} cm with a Hall mobility of 0.749 cm{sup 2} V{sup -1} s{sup -1}, carrier concentration of 8.02 x 1018 cm{sup -3}, and transmittance of about 80% in visible range showing good crystallinity with prior c-axis orientation. > A shallow acceptor level of 91 meV is identified from free-to-neutral-acceptor transitions. > Another deep level of 255 meV was ascribed to Li{sub Zn}-Li{sub i} complex. - Abstract: Zinc oxide thin films with low resistivity have been deposited on glass substrates by Li-N dual-acceptor doping method via a modified successive ionic layer adsorption and reaction process. The thin films were systematically characterized via scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray diffraction, ultraviolet-visible spectrophotometry and fluorescence spectrophotometry. The resistivity of zinc oxide film was found to be 1.04 {Omega} cm with a Hall mobility of 0.749 cm{sup 2} V{sup -1} s{sup -1} and carrier concentration of 8.02 x 10{sup 18} cm{sup -3}. The Li-N dual-acceptor doped zinc oxide films showed good crystallinity with prior c-axis orientation, and high transmittance of about 80% in visible range. Moreover, the effects of Li doping level and other parameters on crystallinity, electrical and ultraviolet emission of zinc oxide films were investigated.

Thymus transplantation for complete DiGeorge syndrome

DEFF Research Database (Denmark)

Davies, E Graham; Cheung, Melissa; Gilmour, Kimberly

2017-01-01

BACKGROUND: Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). METHODS: Twelve patients with cDGS underwent transplantation with allogeneic cultured thymus. OBJECTIVE: We sought to confirm and extend the results previously obtained in a ...

Magnus Georg von Paucker (1787-1855) / Eckhard Spring

Index Scriptorium Estoniae

Spring, Eckhard

2013-01-01

Eestis sündinud ja Tartu Ülikoolis õppinud silmapaistvast baltisaksa teadlasest ja tema lapselapsest Alexandrine Pauckerist. 23. novembril 2012 Jelgavas/Mitaus toimunud Magnus Georg von Pauckerile pühendatud teaduskonverentsist

St. George Feast: Relation to Eastern Legends and Cults [In Bulgarian

Directory of Open Access Journals (Sweden)

S. Rulinski

2016-07-01

Full Text Available The article examines George as a counterpart to the Sumerian god Ninurta. Feast St. George boasts Georgy feat - creation of the world. The date of the feast – 6th of May, is commented in its relation to the astronomical arguments and Sumerian ancient texts. The main rituals of the feast are described. The most typical folk songs devoted to St. Georgy are listed in the paper appendix.

Georges Duby et les Études d'histoire rurale

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Laurent Feller

2008-01-01

Full Text Available Comme tous les grands artistes, Georges Duby a eu plusieurs périodes. Les études d’histoire rurale ont été la première d’entre elles. De 1952 au milieu des années 1970, Georges Duby a eu une production soutenue et, à tous points de vue importante. Il y eut d’abord les grands ouvrages, sa thèse, sur le Mâconnais qui est aussi un ouvrage traitant des questions rurales dans ce qu’elles peuvent avoir de plus concret et de plus élémentaire. En 1962, L’économie rurale et la vie des campagnes marque...

In vitro effects of metals and pesticides on dehydrogenase activity in ...

African Journals Online (AJOL)

AJB SERVER

2007-01-04

Jan 4, 2007 ... Lin CH, Lerch RN, Kremer RJ, Garrett HC, Udawatta RP, George MF. (2005). Soil microbiological activities in vegetative buffer strips and their association with herbicide degradation. AFTA 2005 Conference. Proceedings pp 1 – 10. Mårtensson AM (1992). Effects of agrochemicals and heavy metals on.

George MacDonald's Estimate of Childhood

Science.gov (United States)

Pridmore, John

2007-01-01

The nineteenth-century fantasy writer George MacDonald believed that "it is better to be a child in a green field than a knight of many orders." In this paper, I shall explore the bearing of this high estimate of childhood on spiritual education. MacDonald explores the spirituality of the child in his essay "A Sketch of Individual Development" and…

Final Comments from Professors George and Beane.

Science.gov (United States)

Beane, James; George, Paul S.

1996-01-01

Concludes this journal focus section on curriculum integration with transcripts of questions asked by conference attendees and answers by Professors Beane and George. Areas addressed included experience levels with children and teachers, studies that point to the failure of curriculum integration, and how teachers can continue curriculum…

77 FR 59035 - Notice of Intent To Rule on Request To Release Airport Property at the St. George Airport, St...

Science.gov (United States)

2012-09-25

... To Release Airport Property at the St. George Airport, St. George, UT AGENCY: Federal Aviation... rule and invite public comment on the release of land at St. George Airport under the provisions of..., City of St. George, Utah, at the following address: Mr. Gary Esplin, City Manager, City of St. George...

Il Cabinet d'amateur di Georges Perec

Directory of Open Access Journals (Sweden)

Valeria Cammarata

2011-06-01

Full Text Available In 1979 one year after the publication of La vie mode d’emploi, George Perec wrote Cabinet d’amateur. Histoire d’un tableau, in which he tells the story of a painting belonging to the genre of the cabinet d’amateur, also known as kunst- und wunderkammer. It is a collection of different paintings, usually belonging to a rich man or a notable, portrayed (once again in a single picture celebrating the magnificence of this more or less real collection. As for the pictorial genre, so the short novel is the celebration of the images collected by George Perec in his previous masterpiece, La vie mode d’emploi. This is why I assume this work to be referable to the genre of structural homology more than to that of ékphrasis, being the pictorial structure not only the thematic inspiration or motif of the novel but its own underlying structure

Sorose suured soovid / George Soros ; interv. Neeme Raud

Index Scriptorium Estoniae

Soros, George, 1930-

2006-01-01

Miljardär ja filantroop George Soros vastab küsimustele, mis puudutavad tema raamatut "Ekslikkuse ajastu", kriitika USA kui maailma korratuse ühe põhjustaja suhtes, terroriohu vähendamist maailmas, avatud ühiskonnast

Georg Franz Buquoy und "La famosissima Notte"

Czech Academy of Sciences Publication Activity Database

Konečný, Lubomír

-, 0016 (2011), s. 1-9 ISSN 2190-3328 Institutional research plan: CEZ:AV0Z80330511 Keywords : Georg Franz August de Longueval, Count Buquoy * Antonio Allegri * Il Correggio Subject RIV: AL - Art, Architecture, Cultural Heritage http://www.riha-journal.org/articles/2011/2011-jan-mar/konecny-buquoy-famosissima-notte

In Praise of George Peabody, 1795-1869.

Science.gov (United States)

Parker, Franklin

1994-01-01

One of several papers on self-made millionaire and educational philanthropist George Peabody defends Peabody's philanthropy against those who criticized him as miserly, highlighting his establishment of colleges, libraries, museums, hospitals, and other charities. The paper details his life, work, politics, and death, describing the causes that he…

George A. Towns Elementary School. Atlanta, Georgia

Science.gov (United States)

Burt, Ralph H.

1976-01-01

A project testing solar heating and cooling in an existing building, the George A. Towns Elementary School, is intended to provide information on system design and performance, allow the identification and correction of problems encountered in installing large units, and gauge community/user reaction to solar equipment. (Author/MLF)

George F. Kennan and the Division of Europe

Czech Academy of Sciences Publication Activity Database

Smetana, Vít

2013-01-01

Roč. 15, č. 4 (2013), s. 225-232 ISSN 1520-3972 Institutional support: RVO:68378114 Keywords : George F. Kennan * Cold War * U.S. foreign policy Subject RIV: AB - History Impact factor: 0.349, year: 2013

O conceito "socialização" caiu em desuso? Uma análise dos processos de socialização na infância com base em Georg Simmel e George H. Mead Is the " socialization" concept outdated? An analisis of the socialization processes in childhood according to Georg Simmel and George H. Mead

Directory of Open Access Journals (Sweden)

Tamara Grigorowitschs

2008-04-01

Full Text Available O artigo apresenta uma leitura das obras de George H. Mead e Georg Simmel a respeito do conceito processos de socialização à luz de questões suscitadas no interior do domínio da sociologia da infância. Aborda o desenvolvimento do conceito processos de socialização em Simmel e correlaciona as concepções simmelinas com a obra de Mead a respeito do desenvolvimento do self, com o objetivo de definir os processos de socialização na infância. Visa demonstrar como as obras de Simmel e Mead permitem pensar a infância como um período específico dos processos de socialização, em que as crianças desempenham papéis ativos na construção de seus selves individuais e da sociedade e cultura em que estão inseridas.This paper presents an analysis of George H. Mead's and Georg Simmel's works about the concept of socialization processes in the light of questions arised in the scope of childhood sociology. It approaches the development of Simmel's socialization processes concept and establishes a correlation between the Simmelian conceptions and Mead's work about the self development, in an attempt to define the socialization processes in childhood. It is intended to demonstrate how Simmel's and Mead's works allow us to think about childhood as a specific period of the socialization processes in which children play active roles in building their individual selves, as well as the society and culture they are in.

DiGeorge Syndrome: a not so rare disease

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Angela BF Fomin

2010-01-01

Full Text Available INTRODUCTION: The DiGeorge Syndrome was first described in 1968 as a primary immunodeficiency resulting from the abnormal development of the third and fourth pharyngeal pouches during embryonic life. It is characterized by hypocalcemia due to hypoparathyroidism, heart defects, and thymic hypoplasia or aplasia. Its incidence is 1:3000 live births and, despite its high frequency, little is known about its natural history and progression. ←This is probably due to diagnostic difficulties and the great variety of names used to describe it, such as velocardiofacial, Shprintzen, DiGeorge, and CATCH 22 Syndromes, as well as conotruncal facial anomaly. All represent the same genetic condition, chromosome 22q11.2 deletion, which might have several clinical expressions. OBJECTIVES: To describe clinical and laboratorial data and phenotypic characteristics of patients with DiGeorge Syndrome. METHODS: Patients underwent standard clinical and epidemiological protocol and tests to detect heart diseases, facial abnormalities, dimorphisms, neurological or behavioral disorders, recurrent infections and other comorbidities. RESULTS: Of 14 patients (8m - 18y11m, only one did not have 22q11.2 deletion detected. The main findings were: conotruncal malformation (n = 12, facial abnormalities (n = 11, hypocalcemia (n = 5 and low lymphocyte count (n=2. CONCLUSION: The authors pointed out the necessity of DGS suspicion in all patient presenting with heart defects, facial abnormalities (associated or not with hypocalcemia, and immunological disorders because although frequency of DGS is high, few patients with a confirmed diagnosis are followed up.

"Georg" : za 13 sjomotshnõhh dnei do filma / Marko Matvere ; intervjueerinud Boris Tuch

Index Scriptorium Estoniae

Matvere, Marko, 1968-

2006-01-01

Peeter Simmi mängufilmi "Georg" võtteperioodi lõpuni on jäänud loetud päevad. Filmist ja oma tegelaskujust räägivad näitlejad Marko Matvere, Anastasia Makejeva (artiklis ekslikult Matvejeva), laulja Renars Kaupers. Filmi stsenarist Mati Põldre räägib Georg Otsa ja KGB suhetest

Language, literature and theory in Georges Perec

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Jacques Fux

2013-07-01

Full Text Available This article approaches some possible relations between space and literature within the work of the French writer Georges Perec. The book Espèces d’espaces, published in 1974, is taken as a major reference for a reflection about how its narrative structure produces displacements in its fictional status.

Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors.

Science.gov (United States)

Dahlin, Joakim S; Malinovschi, Andrei; Öhrvik, Helena; Sandelin, Martin; Janson, Christer; Alving, Kjell; Hallgren, Jenny

2016-01-28

Mast cells are rare tissue-resident immune cells that are involved in allergic reactions, and their numbers are increased in the lungs of asthmatics. Murine lung mast cells arise from committed bone marrow-derived progenitors that enter the blood circulation, migrate through the pulmonary endothelium, and mature in the tissue. In humans, mast cells can be cultured from multipotent CD34(+) progenitor cells. However, a population of distinct precursor cells that give rise to mast cells has remained undiscovered. To our knowledge, this is the first report of human lineage-negative (Lin(-)) CD34(hi) CD117(int/hi) FcεRI(+) progenitor cells, which represented only 0.0053% of the isolated blood cells in healthy individuals. These cells expressed integrin β7 and developed a mast cell-like phenotype, although with a slow cell division capacity in vitro. Isolated Lin(-) CD34(hi) CD117(int/hi) FcεRI(+) blood cells had an immature mast cell-like appearance and expressed high levels of many mast cell-related genes as compared with human blood basophils in whole-transcriptome microarray analyses. Furthermore, serglycin, tryptase, and carboxypeptidase A messenger RNA transcripts were detected by quantitative reverse transcription-polymerase chain reaction. Altogether, we propose that the Lin(-) CD34(hi) CD117(int/hi) FcεRI(+) blood cells are closely related to human tissue mast cells and likely constitute an immediate precursor population, which can give rise to predominantly mast cells. Furthermore, asthmatics with reduced lung function had a higher frequency of Lin(-) CD34(hi) CD117(int/hi) FcεRI(+) blood mast cell progenitors than asthmatics with normal lung function. © 2016 by The American Society of Hematology.

Initial results on computational performance of Intel Many Integrated Core (MIC) architecture: implementation of the Weather and Research Forecasting (WRF) Purdue-Lin microphysics scheme

Science.gov (United States)

Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

2014-10-01

Purdue-Lin scheme is a relatively sophisticated microphysics scheme in the Weather Research and Forecasting (WRF) model. The scheme includes six classes of hydro meteors: water vapor, cloud water, raid, cloud ice, snow and graupel. The scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. In this paper, we accelerate the Purdue Lin scheme using Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi is a high performance coprocessor consists of up to 61 cores. The Xeon Phi is connected to a CPU via the PCI Express (PICe) bus. In this paper, we will discuss in detail the code optimization issues encountered while tuning the Purdue-Lin microphysics Fortran code for Xeon Phi. In particularly, getting a good performance required utilizing multiple cores, the wide vector operations and make efficient use of memory. The results show that the optimizations improved performance of the original code on Xeon Phi 5110P by a factor of 4.2x. Furthermore, the same optimizations improved performance on Intel Xeon E5-2603 CPU by a factor of 1.2x compared to the original code.

Bulgaria and Serbia in the historical works of George Akropolites and George Pachymeres

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Stanković Vlada

2009-01-01

Full Text Available The paper analyzes the well-known historical works of George Akropolites and George Pachymeres from the viewpoint of their literary composition structure, lexica and narrative techniques used for describing events and personalities from Bulgaria and Serbia. An attempt is made to surpass the 'traditional' methodology and the usually applied standard approach that focuses almost exclusively to the search for the 'strong' historical facts in these literary works par excellence, in that way overlooking their strong literary character, careful expressions, sometimes evident and sometimes more subtle style differences whose purpose was to underline the focal points and the conclusions of the content of the stories - in short, the information and the stories about Bulgaria and Serbia by Akropolites and Pachymeres are analyzed in their entirety, viewed as the integral parts of the complex literary works, and not as isolated episodes, divided from the rest of the narrative. The ways in which George Akropolites depicted and described deaths of the Bulgarian rulers were studied as one of the best examples of his conscious endeavors to bring the literary style of his History in accord with his own judgments about the rulers of the neighboring country. Scenes of death, conspicuously frequent in Akropolites' relatively short historical work, play an important role in characterizing personalities, and the same principle which Akropolites uses for judging the Byzantines is applied to the Bulgarians as well: generally positive opinion about somebody's life and achievements is emphasized with a depiction of his death in a positive way (Ivan II Asen, and vice versa, Akropolites' 'villains' receive their horrible deaths as a deserved punishment for their bad deeds (Kalojan's death. On the other hand, Akropolites' scarce information about Serbs is supplemented with his depiction of the Serbian king Uroš (1243-1276, and his stance after the death of John Batatzes

George Soros : maailma hädad sünnivad avatuse ja suletuse vastuoludest / George Soros ; interv. Urmet Kook

Index Scriptorium Estoniae

Soros, George, 1930-

2004-01-01

George Soros vastab küsimustele, kas postkommunistlikel riikidel oleks olnud mõttekas ja võimalik valida veidi pehmem tee turumajandusele üleminekul, kas ta usub liberaalse demokraatia lõplikku võidukäiku maailmas, millised on suurimad ohud tänapäeva maailma ees, samuti küsimustele demokraatlike riikide alliansi otstarbe ja mahajäänud ühiskondade jaluleaitamise kohta

Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B.

Science.gov (United States)

Lee, Chih-Yung Sean; Lu, Tu; Seydoux, Geraldine

2017-11-07

Nanos RNA-binding proteins are required for germline development in metazoans, but the underlying mechanisms remain poorly understood. We have profiled the transcriptome of primordial germ cells (PGCs) lacking the nanos homologs nos-1 and nos-2 in C. elegans. nos-1nos-2 PGCs fail to silence hundreds of transcripts normally expressed in oocytes. We find that this misregulation is due to both delayed turnover of maternal transcripts and inappropriate transcriptional activation. The latter appears to be an indirect consequence of delayed turnover of the maternally-inherited transcription factor LIN-15B, a synMuvB class transcription factor known to antagonize PRC2 activity. PRC2 is required for chromatin reprogramming in the germline, and the transcriptome of PGCs lacking PRC2 resembles that of nos-1nos-2 PGCs. Loss of maternal LIN-15B restores fertility to nos-1nos-2 mutants. These findings suggest that Nanos promotes germ cell fate by downregulating maternal RNAs and proteins that would otherwise interfere with PRC2-dependent reprogramming of PGC chromatin.

Prolífica George Sand

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Àngels Santa

2014-04-01

Full Text Available A propósito de las obras de George Sand, Œuvres complètes. Sous la direction de Béatrice Didier. 1841-1842.Un hiver à Majorque. Édition critique par Angela Ryan. Horace.Édition critique par Jeanne Brunereau (París, Honoré Champion, 2013, 748 p. ISBN : 9782745319265 y Œuvres complètes. ́Sous la direction de Béatrice Didier. 1849.La petite Fadette. Édition critique par Andrée Mansau (París, Honoré Champion, 2013, 345p. ISBN : 9782745319203

78 FR 76189 - Supplemental Environmental Impact Statement for the Route 460 Location Study, Prince George...

Science.gov (United States)

2013-12-16

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Supplemental Environmental Impact Statement for the Route 460 Location Study, Prince George County to Suffolk, Virginia AGENCY: Federal... roughly parallel to the existing Route 460 corridor between Interstate 295 in Prince George County and...

St George the dragon-slayer at Prague Castle - the eternal pilgrim without a home?

Czech Academy of Sciences Publication Activity Database

Benešovská, Klára

2007-01-01

Roč. 55, č. 1 (2007), s. 28-39 ISSN 0049-5123 Institutional research plan: CEZ:AV0Z80330511 Keywords : Gothic bronze sculpture * St George the dragon -slayer * Martin and George of Cluj * Prague Castle Subject RIV: AL - Art, Architecture, Cultural Heritage http://www.umeni-art.cz/cz/soubory/benesovska.pdf

George A. Miller (1920–2012)

OpenAIRE

Pinker, Steven

2013-01-01

Presents an obituary for George A. Miller (1920—2012). Miller ranks among the most important psychologists of the 20th century. In addition to writing one of the best known papers in the history of psychology (“The Magical Number Seven, Plus or Minus Two: Some Limits on Our Capacity for Processing Information,” published in Psychological Review in 1956), Miller also fomented the cognitive revolution, invented psycholinguistics and cognitive psychology, imported powerful ideas from the theorie...

Autobiography of Sir George Biddell Airy

Science.gov (United States)

Airy, George Biddell; Airy, Wilfred

2010-06-01

Preface; 1. Personal sketch of George Biddell Airy; 2. From his birth to his taking his B.A. degree; 3. At Trinity College, Cambridge; 4. At Cambridge Observatory; 5. At Greenwich Observatory, 1836-1846; 6. At Greenwich Observatory, 1846-1856; 7. At Greenwich Observatory, 1856-1866; 8. At Greenwich Observatory, 1866-1876; 9. At Greenwich Observatory to his resignation in 1881; 10. At the White House, Greewich, to his death; Appendix: List of printed papers; Index.

Catalog of the George Alan Connor Esperanto Collection.

Science.gov (United States)

Smith, Karin, Comp.; Haake, Susan, Comp.

This catalog inventories the collection of books, monographs, serials and periodicals, dictionaries, pamphlets, ephemera, and correspondence concerning Esperanto in the collection of George Alan Connor housed at the University of Oregon Library. Overall, the catalog contains approximately 475 serial entries and 3,000 author entries. Connor was a…

Traitement statistique des distorsions non-linéaires pour la restauration des enregistrements sonores.

OpenAIRE

Picard , Guillaume

2006-01-01

L'objet de la thèse est l'étude, la modélisation et le traitement des distorsions non linéaires sonores, pour lesquelles les techniques actuelles s'avèrent impuissantes. L'approche retenue consiste à représenter, globalement, à la fois le signal audio à restaurer et le processus de distorsion, dans le cadre d'un modèle statistique. Cette approche présente un bon compromis entre une souhaitable généricité -possibilité de traiter à l'aide d'une méthode globale plusieurs types de distorsions- et...

Hans Joas & Daniel R. Huebner (eds.), The Timeliness of George Herbert Mead

OpenAIRE

Baggio, Guido

2018-01-01

The Timeliness of George Herbert Mead is a significant contribution to the recent “Mead renaissance.” It gathers some contributions first presented at the conference celebrating the 150th anniversary of the birth of George Herbert Mead held in April 2013 at the University of Chicago and organized by Hans Joas, Andrew Abbott, Daniel Huebner, and Christopher Takacs. The volume brings scholarship on G. H. Mead up to date highlighting Mead’s relevance for areas of research completely ignored by p...

Reduction of EMC Emissions in Mixed Signal Integrated Circuits with Embedded LIN Driver

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P. Hartl

2016-06-01

Full Text Available This paper describes several methods for reduction of electromagnetic emissions (EME of mixed signal integrated circuits (IC. The focus is on the impact that a LIN bus communication block has on a complex IC which contains analog blocks, noisy digital block, micro-core (µC and several types of memories. It is used in an automotive environment, where EMC emission reduction is one of the key success factors. Several proposed methods for EME reduction are described and implemented on three test chips. These methods include current consumption reduction, internal on-chip decoupling, ground separation and different linear voltage regulator topologies. Measurement results of several fabricated test chips are shown and discussed.

THE ONEIRIC AUTOBIOGRAPHY OF GEORGES PEREC.

Science.gov (United States)

Schwartz, Henry P

2016-01-01

Georges Perec's book La Boutique Obscure (1973; translated into English in 2012) serves as the basis for this paper. The book is a collection of dreams that its author dreamed from May 1968 to August 1972. The present author treats these dreams as chapters in a bizarre autobiography, elaborating Perec's life through a discussion of those dreams and using them as a starting point with which to discuss his views of dream interpretation and the role of dreams in psychoanalysis. © 2016 The Psychoanalytic Quarterly, Inc.

Applying a Multiple Screening Program Aided by a Guideline-driven Computerized Decision Support System—A Pilot Experience in Yun-Lin, Taiwan

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Jou-Wei Lin

2007-01-01

Conclusion: A computer-aided screening program driven by the US Preventive Services Task Force recommendations has been successfully implemented in Yun-Lin, Taiwan, and provided useful information about local epidemiology and implications for future health policy making. [J Formos Med Assoc 2007; 106(1:58-68

Georges et le code secret

CERN Document Server

Hawking, Lucy; Parsons, Gary

2015-01-01

À Foxbridge, Georges et Annie s'ennuient, ils rêvent de repartir dans l'espace pour de nouvelles aventures intergalactiques. Pourtant, sur la terre ferme, il se passe des choses étranges... L'argent s'envole des distributeurs de billets, les avions refusent de décoller et les caisses enregistreuses des supermarchés ne fonctionnent plus... Quel chaos ! Il semblerait qu'un bug planétaire ait déréglé tous les systèmes informatiques. S'ils veulent découvrir ce qui se cache derrière tout ça, les deux amis devront voyager plus loin que jamais dans l'espace...

Georges Perec's literary staging

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Ewelina Woźniak-Czech

2017-12-01

Full Text Available The purpose of this sketch to present Georges Perec’s work in the context of drama. As Perec wrote just one play for the theater, it’s hard to call him a dramatist. However, it is easy to see that all the literary tricks he uses in his works are a part of a well-thought-out game. The author of Life a User’s Manual employs and interweaves various literary conventions, prompts dialogue between his own works and draws the reader into the very center of his tricks, nuances and simulations. Perec’s writing could be deemed a pure act of dramatization, where the author himself, to some extent, takes on the role of director, making his audience not so much the recipients of his texts but the actors performing them.

La politique commerciale de George W. Bush : rupture ou continuité ? American Trade Policy under George W. Bush: Continuity or Change?

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Jean-Baptiste Velut

2010-03-01

Full Text Available Cet article se propose de dresser un bilan critique de la politique commerciale du Président George W. Bush. Dans un premier temps, il compare les perspectives idéologiques et les ambitions politiques du leader républicain à celles de son prédécesseur démocrate, Bill Clinton, avant de mettre l’accent sur les nouvelles données du contexte politique et économique des années 2000. Ces éléments introductifs serviront de fondations, d’une part, pour l’étude de la gestion des relations commerciales entre les États-Unis et leurs principaux partenaires économiques, et d’autre part pour l’analyse de la stratégie de « libéralisation compétitive » adoptée par George W. Bush aux niveaux multilatéral, régional et bilatéral. L’objectif est double : déterminer les lignes de rupture et de continuité entre le président républicain et son prédécesseur ; et établir un bilan des principales initiatives commerciales lancées par l’administration Bush dans le but de mieux comprendre les nouveaux défis intérieurs et internationaux auxquels son successeur sera confronté.This article offers a critical assessment of American trade policy under George W. Bush. It begins by comparing his views and political ambitions with those of his Democratic predecessor, Bill Clinton, before highlighting the new political and economic context of the 2000s. These elements provide crucial background, first to study the evolution of America’s relations with its top trading partners and second to analyze the strategy of “competitive liberalization” undertaken by the administration at the multilateral, regional and bilateral levels. This article has two objectives: 1 determining trends of continuity and change between George W. Bush and his predecessor; 2 assessing the trade policy initiatives undertaken by the Republican administration in order to understand the domestic and international challenges with which the next President

Adequacy of environmental information for outer continental shelf oil and gas decisions: Georges Bank. Final report

International Nuclear Information System (INIS)

1991-01-01

Georges Bank, a large, shallow marine bank with important fishery resources and possibly important oil and gas resources, lies east of Massachusetts in the territorial waters of both the United States and Canada. The Department of the Interior has planned since 1974 to lease parts of the north Atlantic outer continental shelf (OCS)--including part of Georges Bank--for oil and gas exploration. As a result of public concern about the environmental impacts of oil and gas production on the U.S. OCS, Congress declared a moratorium on drilling on Georges Bank and an area to the southwest. The report--by the NRC's Committee to Review the Outer Continental Shelf Environmental Studies Program and its panels on physical oceanography, ecology, and socioeconomics--reviews the adequacy of information bearing on the potential environmental impacts of OCS oil and gas activities for the Georges Bank sale area

Areva's challenge for ''Georges Besse 2''

International Nuclear Information System (INIS)

Jemain, A.

2003-01-01

For its future uranium enrichment plant of its Tricastin site (Drome, France), the world nuclear leader Areva has abandoned the gaseous diffusion technique (of French origin) for the centrifugation technique, more economical and modular. This future plant, named 'Georges Besse 2' will require 3 billions of euros of investment and will supply a world market also estimated to 3 billions of euros and shared between Areva, Urenco (UK), Usec (US), Minatom (Russia), JNC (Japan) and CNNC (China). The first batches of enriched uranium will be produced using a thousand of centrifuges by 2007. (J.S.)

The Second Administration of George W. Bush and U.S.-Russia Relations

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Rybalko Olga

2014-12-01

Full Text Available This article is devoted to the analysis of changes in the U.S.-Russia relationships during the presidency of George W. Bush and to the detection of the origins of these changes. The attention is paid to conceptual foreign policy views of the most influential members of administration. The renewal of staff in U.S. administration was one of the important factors of toughening the Russian course of the American foreign policy. At the beginning of the second presidency of George Bush the ratio of forces in the American Congress changed. Opposition forces received the majority in the Congress. This circumstance became the other reason of change of the U.S.-Russia relationships. The bilateral relations during the specified period were complicated by aspiration of the USA to strengthen the influence on the territories of the Post-Soviet states. It caused discontent of Moscow. At the same time, some aspects of the Russian-Iranian nuclear cooperation caused criticism of Washington. The role of personal diplomacy is noted as a factor of forming bilateral relations. During the second term of the presidency of George W. Bush this factor didn't lose its value in comparison with the first term. The article gives the assessment of work of the Bush’s second administration at the Russian direction. The author notes the American focus on the strategy of “selective partnership” with Russia. The conclusion is drawn on George Bush's aspiration to preservation of balance in the U.S.-Russia relations under the conditions of increasing strains.

Studien zum "Horrendum Bellum Grammaticale" des Justus Georg Schottelius (1673): Vorstellung des Dissertationsvorhabens / Tuomo Fonsén

Index Scriptorium Estoniae

Fonsén, Tuomo, 1976-

2006-01-01

Autori dissertatsioonist, mis tutvustab Justus Georg Schotteliuse ladinakeelset allegoorilist saksa keele grammatikat ja keeleajalugu käsitlevat tööd 17. sajandist. Schottelius, Justus Georg. Horrendum Bellum Grammaticale Teutonum antiquissimorum [...]. Braunschweig : [s.n.], 1673

George W. Bush in Political Time: The Janus Presidency

NARCIS (Netherlands)

Magliocca, G.N.

2009-01-01

This essay places George W. Bush's presidency and the Bush administration in some historical context by applying the model of “political time” developed in recent books by Stephen Skowronek (2008) and Keith Whittington (2007). My thesis is that Bush's political failure during his second term was

George Herbert Mead, Um, osoba i društvo

OpenAIRE

Bačeković, Alica

2004-01-01

Prikaz knjige George Herbert Mead, Um, osoba i društvo sa stajališta socijalnog biheviorista, priredio i uvod napisao Charles W. Morris, s engleskoga preveo Srđan Dvornik, Naklada Jesenski i Turk, Hrvatsko sociološko društvo, Zagreb 2003, xxx + 392 str

Prescient … and Not Always Accounted For: The Wisdom and Foresight of George A. Roeper

Science.gov (United States)

Delisle, Jim; Ruff, Marcia

2016-01-01

When George A. Roeper enlisted the aid of Dr. A. Harry Passow and other leaders in the field to help George convert his Michigan independent school to focus on gifted children in 1956, there was only one other elementary school in the country at the time devoted exclusively to gifted child education. Though his wife and school cofounder,…

Stochastic programming the state of the art in honor of George B. Dantzig

CERN Document Server

2011-01-01

From the Preface… The preparation of this book started in 2004, when George B. Dantzig and I, following a long-standing invitation by Fred Hillier to contribute a volume to his International Series in Operations Research and Management Science, decided finally to go ahead with editing a volume on stochastic programming. The field of stochastic programming (also referred to as optimization under uncertainty or planning under uncertainty) had advanced significantly in the last two decades, both theoretically and in practice. George Dantzig and I felt that it would be valuable to showcase some of these advances and to present what one might call the state-of- the-art of the field to a broader audience. We invited researchers whom we considered to be leading experts in various specialties of the field, including a few representatives of promising developments in the making, to write a chapter for the volume. Unfortunately, to the great loss of all of us, George Dantzig passed away on May 13, 2005. Encouraged by...

The conceptualization of love in religious thought of George Florovsky and Michael Pomazansky

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Pavenkov Oleg Vladimirovich

2015-04-01

Full Text Available The present article is concerned with the question of conceptualization of love in works of Fr. George Florovsky and Fr. Michael Pomazansky, Russian religious thinkers and theologists. We are studying the meaning and appropriacy of two words, ‘love’ (English and ‘любовь’ (Russian, that are the best to represent the agapelogical positive evaluation in Russian religious thought. Data for study was taken from ten different articles and extracts from books written by Fr. George Florovsky and Fr. Michael Pomazansky. On the basis of this analysis we develop semantic explications of words ‘love’ and ‘любовь’ as Christian spiritual concepts within the framework of theoretical approach of Natural Semantic Metalanguage (NSM. In summary we state that this article discusses, describes and determines some similarities and differences in understanding of concept ‘love’ in the affore-referenced works by Fr. George Florovsky and Fr. Michael Pomazansky.

Festschrift Charpak (Georges) on his 65th birthday

CERN Document Server

Lehmann, Pierre; Rubbia, Carlo; Saudinos, Jean; CERN. Geneva

1989-01-01

On the occasion of the 65th birthday of Georges Charpak and of his retirement, the Director-General and the EP Division invite you to a symposium in his h. Chairman : P. Lehmann. - Opening address : C. Rubbia. - Message from V. Weisskopf. - L. Lederman : Superstrings needs sealing wax. - J. Saudinos : Quelques applications des detecteurs gazeux a la medecine et a la biologie.

Tuning the Self : George Herbert's poetry as cognitive behaviour

NARCIS (Netherlands)

van Es, Eelco

2013-01-01

This book provides a cognitive analysis of the poetry of George Herbert (1593- 1633). From Herbert’s own thinking, recorded in his prose treatises, can be deduced that his poems should serve a specific function: teaching self-knowledge to his readers. Self-knowledge is a necessary skill, to be

Georges Lema\\^itre: Life, Science and Legacy

OpenAIRE

Mitton, Simon

2016-01-01

This paper celebrates the remarkable life, science and legacy of Abb\\'e Georges Lema\\^itre, the Belgian cleric and professor of physics; he was the architect of the fireworks model for the origin of the universe. He died half a century ago, three days after learning that Arno Penzias and Robert Wilson had discovered the cosmic microwave background. Despite being gravely ill from leukaemia, Lema\\^itre lucidly praised this news, which confirmed the explosive genesis of our universe.

George de Hevesy (1885 - 1966), founder of radioanalytical chemistry

International Nuclear Information System (INIS)

Niese, S.

2006-01-01

George de Hevesy has founded Radioanalytical Chemistry and Nuclear Medicine, discovered the element hafnium and first separated stable isotopes. For all these different important achievements he was nominated for the Nobel Prize. On occasion of his discovery of activation analysis 70 years ago his life and work will be illustrated. (author)

George Smoot, Blackbody, and Anisotropy of the Cosmic Microwave Background

Science.gov (United States)

the Cosmic Microwave Background Radiation Resources with Additional Information * Videos 'George Smoot anisotropy of the cosmic microwave background radiation." '1 Smoot previously won the Ernest Orlando . Smoot, blackbody, and anisotropy of the Cosmic Microwave Background (CMB) radiation is available in full

Monogamy of entanglement and teleportation capability

International Nuclear Information System (INIS)

Lee, Soojoon; Park, Jungjoon

2009-01-01

The monogamy inequality in terms of the concurrence, called the Coffman-Kundu-Wootters inequality [V. Coffman et al., Phys. Rev. A 61, 052306 (2000)], and its generalization [T. J. Osborne and F. Verstraete, Phys. Rev. Lett. 96, 220503 (2006)] hold on general n-qubit states including mixed ones. In this Brief Report, we consider the monogamy inequalities in terms of the fully entangled fraction and the teleportation fidelity. We show that the monogamy inequalities do not hold on general mixed states, while the inequalities hold on n-qubit pure states.

75 FR 31509 - Rescinding the Notice of Intent for an Environmental Impact Statement: Prince George's County, MD

Science.gov (United States)

2010-06-03

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Rescinding the Notice of Intent for an Environmental Impact Statement: Prince George's County, MD AGENCY: Federal Highway Administration. ACTION... Statement that was issued on June 11, 2008, for a proposed roadway improvement project in Prince George's...

On Some Philosophical Aspects of the Background to Georg Cantor’s theory of sets

OpenAIRE

Tapp, Christian

2011-01-01

Georg Cantor a cherché à assurer les fondements de sa théorie des ensembles. Cet article présente les differentiations cantoriennes concernant la notion d’infinité et une perspective historique de l’émergence de sa notion d’ensemble. Georg Cantor sought secure foundations for his set theory. This article presents an account of Cantor’s differentiations concerning the notion of infinity and a tentative historical parsepctive on his notion of set.

GEORG CANTOR’UN SONSUZLARI

OpenAIRE

GÜNEY, Zekeriya; KORKMAZ, Nebiye

2014-01-01

 Özet Georg Cantor, kümeler kuramı ve matematiksel biçimciliğin öncüsüdür. Cantor’un özellikle sonsuzluklarla ilgili çalışmaları matematikte devrim niteliğindedir ve başta topoloji olmak üzere matematiğin çeşitli alanlarında önemli gelişmelere yol açmıştır. Cantor Kuramı’nın pür matematiksel karakteri, matematiğe ve matematik eğitimine yeni bir bakış açısı getirmiş ve matematiğin asıl eğitimsel öneminin, bir zihin jimnastiği olmasından geldiği daha iyi anlaşılır olmuştur. Matematiğin, herhang...

Georg Trakl y la melancolía

Directory of Open Access Journals (Sweden)

Alejandro Peña-Arroyave

2016-01-01

Full Text Available Resumen: Se identificaron algunos aspectos determinantes de la obra poética de Georg Trakl, tomando como punto de partida la conciencia del escritor acerca de la muerte de Dios, desde la perspectiva de Nietzsche. Se hizo un énfasis sobre la melancolía, soporte de la creación, testimonio y reconocimiento del errar y el duelo del hombre, a partir de la cual el autor pudo expresar el desconsuelo por la ruina y el ocaso de Occidente.

[Heavy metal pollution characteristics and ecological risk analysis for soil in Phyllostachys praecox stands of Lin'an].

Science.gov (United States)

Fang, Xiao-bo; Shi, Han; Liao, Xin-feng; Lou, Zhong; Zhou, Lyu-yan; Yu, Hai-xia; Yao, Lin; Sun, Li-ping

2015-06-01

An investigation was carried out in an attempt to reveal the characteristics of heavy metals contamination in the soils of Phyllostachys praecox forest in Lin' an. Based on the concentrations of Hg, As, Cu, Pb, Zn, Cd, Cr, Ni, Co and Mn in 160 topsoil samples, the pollution status and ecological risks of heavy metals in the soils were assessed by single factor pollution index, Nemerow integrated pollution index and Hankanson potential ecological risk index. The spatial variability of heavy metal concentrations in the soils closely related to the distribution of traffic, industrial and livestock pollution sources. The average concentrations of Hg, As, Cu, Pb, Zn, Cd, Cr, Ni, Co and Mn in the soils were 0.16, 7.41, 34.36, 87.98, 103.98, 0.26, 59.12, 29.56, 11.44 and 350.26 mg · kg(-1), respectively. Pb, Cd, Zn and Cu concentrations were as 2.89, 1.70, 1.12 and 1.12 times as the background values of soil in Zhejiang Province, respectively. But their concentrations were all lower than the threshold values of the National Environmental Quality Standard for Soil (GB 15618-1995). The average single factor pollution index revealed that the level of heavy metal pollution in the soils was in order of Pb>Cd>Cu= Zn>Hg>As>Ni>Co>Cr>Mn. Pb pollution was of moderate level while Cd, Cu and Zn pollutions were slight. There was no soil pollution caused by the other heavy metals. However, the Nemerow integrated pollution index showed that all the 160 soil samples were contaminated by heavy metals to a certain extent. Among total 160 soil samples, slight pollution level, moderate pollution level and heavy pollution level accounted for 55.6%, 29.4% and 15.0%, respectively. The average single factor potential ecological risk index (Er(i)) implied that the potential ecological risk related to Cd reached moderate level, while the others were of slight level. Furthermore, Cd and Hg showed higher potential ecological risk indices which reached up to 256.82 and 187.33 respectively

GEORG BRANDES AND THE MODERN PROJECT

Directory of Open Access Journals (Sweden)

Jørgen Veisland

2011-01-01

Full Text Available Georg Brandes’ lecture series on The Main Tendencies in 19th Century Literature was initiated in 1871 and consists of a number of innovative interpretations of European literature. Brandes’ interpretations exemplify his interest in the ideals of the Enlightenment: knowledge, liberation, progress and free thought. The lecture series traces a dialectical movement in European literature, described by Brandes as a dialectics between revolution and liberalism on one hand and conservatism and reactionary tendencies on the other. Brandes includes a dialectics between home, i.e. Danishness, and the ‘foreign’; he opens up a dialogue between nationalism and internationalism with the intention of almost literally placing Europe in Denmark and vice versa. The future was going to be realized in the present. Georg Brandes tried to persuade the young writers of Scandinavia to adopt liberalism and naturalism in their novels and dramas, which some of them proceeded to do, convinced as they were that Brandes’ ideas regarding a new ‘debate’, moral and political, in literature, were right. However, they failed to implement these ideas as we can see by a reading of, for example, Jens Peter Jacobsen’s Niels Lyhne (1880; Henrik Ibsen’s Rosmersholm (1886 and Henrik Pontoppidan’s Lykke-Per (1898–1904. Emanicipating the mind and liberating oneself from the reactionary forces of society turned out to be too difficult for the women and men of what Brandes himself referred to as The Modern Breakthrough. Looking at Brandes today we may conclude that he was ahead of his own time as well as ahead of ours. His ideas regarding a new internationalism and liberalism are far from being realized.

St. George at Prague Castle and Perseus: an Impossible Encounter?

Czech Academy of Sciences Publication Activity Database

Bažant, Jan

2015-01-01

Roč. 19, 1/2 (2015), s. 189-201 ISSN 1212-5865 Institutional support: RVO:67985955 Keywords : Bellerophon * St. George * iconography * Prague Castle * classical tradition Subject RIV: AB - History http://studiahercynia.ff.cuni.cz/wp-content/uploads/sites/79/2016/05/jan_bazant_189-201.pdf

Kurt Alfred Georg Mendelssohn 7 January 1906 - 18 September 1980

International Nuclear Information System (INIS)

Shoenberg, D.

1983-01-01

The life, career and main themes of scientific achievement of Kurt Alfred Georg Mendelssohn are described in detail under the headings: early life in Germany, scientific work, early work in Germany, superconductivity, transport properties of metals, liquid helium, medical physics, Oxford and later life. (U.K.)

Festschrift Charpak (Georges) on his 65th birthday

CERN Document Server

Saudinos, Jean; Garwin, Richard L; Uggerhøj, Erik; CERN. Geneva

1989-01-01

On the occasion of the 65th birthday of Georges Charpak and of his retirement, the Director-General and the EP Division invite you to a symposium in his h. Chairman : P. Lehmann. - J. Saudinos : Quelques applications des détecteurs gazeux à la médecine et à la biologie. - E. Uggerhøj : New steps in the channeling of relativistic particles. - R. Garwin : Remarks from the non-physical world. - G. Charpak : Final speech.

DiGeorge Syndrome: a not so rare disease

OpenAIRE

Fomin,Angela BF; Pastorino,Antonio Carlos; Kim,Chong Ae; Pereira,CA; Carneiro-Sampaio,Magda; Abe-Jacob,Cristina Miuki

2010-01-01

INTRODUCTION: The DiGeorge Syndrome was first described in 1968 as a primary immunodeficiency resulting from the abnormal development of the third and fourth pharyngeal pouches during embryonic life. It is characterized by hypocalcemia due to hypoparathyroidism, heart defects, and thymic hypoplasia or aplasia. Its incidence is 1:3000 live births and, despite its high frequency, little is known about its natural history and progression. ?This is probably due to diagnostic difficulties and the ...

Distribution of Anaerobic Hydrocarbon-Degrading Bacteria in Soils from King George Island, Maritime Antarctica.

Science.gov (United States)

Sampaio, Dayanna Souza; Almeida, Juliana Rodrigues Barboza; de Jesus, Hugo E; Rosado, Alexandre S; Seldin, Lucy; Jurelevicius, Diogo

2017-11-01

Anaerobic diesel fuel Arctic (DFA) degradation has already been demonstrated in Antarctic soils. However, studies comparing the distribution of anaerobic bacterial groups and of anaerobic hydrocarbon-degrading bacteria in Antarctic soils containing different concentrations of DFA are scarce. In this study, functional genes were used to study the diversity and distribution of anaerobic hydrocarbon-degrading bacteria (bamA, assA, and bssA) and of sulfate-reducing bacteria (SRB-apsR) in highly, intermediate, and non-DFA-contaminated soils collected during the summers of 2009, 2010, and 2011 from King George Island, Antarctica. Signatures of bamA genes were detected in all soils analyzed, whereas bssA and assA were found in only 4 of 10 soils. The concentration of DFA was the main factor influencing the distribution of bamA-containing bacteria and of SRB in the analyzed soils, as shown by PCR-DGGE results. bamA sequences related to genes previously described in Desulfuromonas, Lautropia, Magnetospirillum, Sulfuritalea, Rhodovolum, Rhodomicrobium, Azoarcus, Geobacter, Ramlibacter, and Gemmatimonas genera were dominant in King George Island soils. Although DFA modulated the distribution of bamA-hosting bacteria, DFA concentration was not related to bamA abundance in the soils studied here. This result suggests that King George Island soils show functional redundancy for aromatic hydrocarbon degradation. The results obtained in this study support the hypothesis that specialized anaerobic hydrocarbon-degrading bacteria have been selected by hydrocarbon concentrations present in King George Island soils.

The Story of Heathcliff’s Journey Back to Wuthering Heights de Lin Haire-Sargeant (1992, ou le « deux en un » de la ré-écriture The Story of Heathcliff’s Journey Back to Wuthering Heights by Lin Haire-Sargeant (1992, and a “Two in one” Rewrite

Directory of Open Access Journals (Sweden)

Isabelle Roblin

2009-10-01

Full Text Available Lin Haire-Sargeant’s 1992 novel The Story of Heathcliff’s Journey Back to Wuthering Heights is typical of the interest shown by contemporary American writers in Victorian novels. It could indeed be classified doubly as a “retro-Victorian novel” since it partly re-writes not only Emily Brontë’s most famous novel, Wuthering Heights, as the title points out, but also, somewhat less obviously, Charlotte Brontë’s Jane Eyre. We will study in this article how Lin Haire-Sargeant’s attempt at re-writing highlights the usual aims of the retro-Victorian novel: taking advantage of the blanks left by the source novels to propose to the reader a modern critical approach, while at the same time being as faithful as possible to the writing conventions of the 19th century, and suggesting another point of view on a well-known story, through a postmodern mixing of historical and fictive characters.

George Herbert Mead's Contribution to the Philosophy of American Education.

Science.gov (United States)

Renger, Paul, III

1980-01-01

George Herbert Mead's general philsophy showed that he regarded the development of distinctively human behavior as essentially the result of an individual's meaningful participation in the social process of the community to which he belongs. Mead believed that education was a social process involving the meaningful interaction and communication…

President Arnold Rüütel andis president George W. H. Bushile üle Maarjamaa Risti / Kärt Ulman

Index Scriptorium Estoniae

Ulman, Kärt

2005-01-01

President Arnold Rüütel andis New Yorgis endisele USA presidendile Georg Bushile Eesti iseseisvuspüüdluste toetamise eest Maarjamaa Risti I klassi ordeni. Vt. samas lühiintervjuud president George W. H. Bushiga. Töövisiit New Yorki 13.-17.09.2005

A shell-derived time history of bomb 14C on Georges Bank and its Labrador Sea implications

International Nuclear Information System (INIS)

Weidman, C.R.; Jones, G.A.

1993-01-01

Bomb-produced radiocarbon has been used in the past as an important tracer of ocean circulation and as a valuable tool for calculating CO 2 air-sea exchange. However, previous studies of the ocean's time-varying bomb 14 C record have been confined exclusively to analyzing banded corals, and thus their application has been limited to the lower latitudes. The first time history of bomb 14 C from the high-latitude North Atlantic Ocean is obtained from a 54-year-old mollusc specimen, (Bivalvia) Arctica islandica, which was collected live from Georges Bank (41 degrees N) in 1990. The annual growth bands of its shell were analyzed for Δ 14 C using accelerator mass spectrometry, producing a Δ 14 C time history from 1939 to 1990. The depleted condition of the Georges Bank bomb 14 C signal relative to two coral-derived North Atlantic Δ 14 C time histories suggests a significant deepwater source for the waters on Georges Bank. Supported by previous work linking the origin of waters on Georges Bank to the Labrador Sea, the Δ 14 C budget on Georges Bank is modeled as Labrador Sea water, which largely becomes confined to the shelf and partially equilibrates with the atmosphere during a 1-year transit time from the Labrador Sea to Georges Bank. This model is also used to estimate a time history of bomb 14 C for the Labrador Sea. Prebomb Δ 14 C values calculated for the surface Labrador Sea suggest that a greater inventory of bomb 14 C has accumulated here than has previously been reported. Deduced variations in the ventilation and/or 14 CO 2 uptake rates in the Labrador Sea correspond with observed changes in surface salinity of the Labrador Sea, suggesting a reduction in deepwater formation during the late 1960s and 1970s. 59 refs., 11 figs., 2 tabs

A MULHER NEGRA E AS RELAÇÕES DE GÊNERO EM MENINO DE ENGENHO DE JOSÉ LINS DO REGO THE BLACK WOMAN AND GENDER RELATIONS IN MENINO DE ENGENHO BY JOSÉ LINS DO REGO

Directory of Open Access Journals (Sweden)

Zélia Monteiro Bora ; Marina Rodrigues de Oliveira

2011-02-01

Full Text Available Os romances do ciclo da cana-de-açúcar, do escritor paraibano José Lins do Rego (1901-1957 e a sua relação com a sociedade e a cultura destacam-se enquanto abordagens ficcionais, através das quais o escritor buscou representar aspectos relevantes para o entendimento das relações de gênero no Nordeste, no começo do século vinte. Tal representação, indiscutivelmente, reflete a perspectiva de um narrador profundamente marcado pelo lugar privilegiado de onde narra e de sua condição existencial, como o neto de um senhor de engenho. Diante desses aspectos, propomo- nos a analisar brevemente as implicações dessa perspectiva sobre a construção simbólica da personagem negra representada no romance. Para tanto, serão utilizados como referenciais críticos, além do citado romance, os estudos de Zagury (1982, Albuquerque Jr. (1999, Azevedo (1996, 2007, Freyre (2006 Chaguri (2009, Schwarz (2008 e Raboni (2010.The so called sugar cane cycle novels by the Parahyban writer Jose Lins do Rego (1901-197 and its relationship with society and culture constitute themselves as fictional approaches through which the writer sought to represent aspects to the understanding of gender relations in the Northeast of Brazil in the early twentieth century. Such representation, undoubtedly reflects the perspective of a narrator deeply marked by the privileged place from which he narrates and his existential condition, as the son of a plantation owner. Given these aspects, we propose to examine briefly the implications of his perspective on the symbolic construction of the black woman characteres represented in the novel. The following

Weak Activity of Haloalkane Dehalogenase LinB with 1,2,3-Trichloropropane Revealed by X-Ray Crystallography and Microcalorimetry▿

OpenAIRE

Monincová, Marta; Prokop, Zbyněk; Vévodová, Jitka; Nagata, Yuji; Damborský, Jiří

2007-01-01

1,2,3-Trichloropropane (TCP) is a highly toxic and recalcitrant compound. Haloalkane dehalogenases are bacterial enzymes that catalyze the cleavage of a carbon-halogen bond in a wide range of organic halogenated compounds. Haloalkane dehalogenase LinB from Sphingobium japonicum UT26 has, for a long time, been considered inactive with TCP, since the reaction cannot be easily detected by conventional analytical methods. Here we demonstrate detection of the weak activity (kcat = 0.005 s−1) of Li...

A Homeland Security Net Assessment Needed Now!

Science.gov (United States)

2015-12-01

George Washington University. Cilluffo argues that the DHS responds to most threats reactively and has only a limited capability for assessing...also the director of the NSA and the two organizations are both located at Fort Meade , Maryland, the two commands have dif- ferent missions and operate...12. 75. David Clark, Thomas Berson, and Herbert S. Lin, eds., At the Nexus of Cybersecurity and Public Policy: Some Basic Concepts and Issues

An attempt of using soil grain size in calculating the capacity of water unavailable to plants / Próba wykorzystania uziarnienia gleby do obliczania zawartości wody niedostępnej dla roślin

Directory of Open Access Journals (Sweden)

Brogowski Zygmunt

2015-03-01

Full Text Available Celem pracy była próba znalezienia możliwości obliczenia ilości wody niedostępnej dla roślin na podstawie uziarnienia gleb. Frakcje o średnicach <0,02 mm gromadzą od 90,1 do 98,8% całkowitej ilości wody niedostępnej dla roślin, a frakcja iłu koloidalnego (<0,002 mm zatrzymuje od 52,1 do 80,1% tej wody. Gromadzenie wody we frakcjach <0,02 mm znacząco zależy od ich składu mineralogicznego. Obecność we frakcjach illitu, chlorytu oraz kaolinitu powoduje zmniejszenie ilości wody niedostępnej nawet o 40% w stosunku do frakcji zbudowanych ze smektytów, wermikulitów oraz próchnicy. Ze względu na duże zróżnicowanie ilości wody niedostępnej dla roślin w poszczególnych frakcjach granulometrycznych <0,02 mm wynikaj¹ce ze zróżnicowania mineralogicznego tych frakcji nie udało się wyprowadzić współczynników pozwalających na obliczenie ilościowe w glebach wody niedostępnej dla roślin wiązanej w mikroporach <0,2 μm.

Drivers Dexterity: George Osodi's Oeuvre on Safety on the Nigerian ...

African Journals Online (AJOL)

This paper attempted a reading of the Nigerian condition using the censure of images culled from an exhibition by the Nigerian photographer George Osodi. Drawing attention to the shapes of the images and imageries that constitute the profile of the condition of a major infrastructure, the road and transportation, I have ...

Residents’ perspectives towards conservation in George Town world heritage city: A post-UNESCO listing scenario

Directory of Open Access Journals (Sweden)

Yoke Mui LIM

2014-12-01

Full Text Available Being inscribed as a UNESCO World Heritage City since 2008, this scenario calls into question the voices, the participation and the aspirations of George Town residents themselves in the process of planning and conserving their city. As an extension of a similar project undertaken in 2006, prior to the UNESCO listing, the present study sought to explore and understand the residents’ perceptions and preferences of George Town as a Heritage City after the UNESCO listing. Using the same set of samples (i.e. 400 inner city residents, the findings from this study revealed the change of residents’ preference as well as their appreciation towards the value of heritage and its economic potential. More respondents are supportive on the protection of heritage buildings and maintaining a heritage city. The older generations are the advocates of the heritage houses and they are more willing to pay higher prices to own a heritage house in the city. heritage awareness, urban conservation, resident perspectives, George Town.

Eesti kriminaalõiguse arenguteed : kolmveerand sajandit esimese kriminaalseadustiku vastuvõtmisest / Georg Ambach

Index Scriptorium Estoniae

Ambach, Georg, 1952-2006

2004-01-01

Karl Saarmannist ja tema teesidest seoses karistusseadustikuga ja tegevusest kriminaalreformi läbiviimisel. Karistusseadustiku eelnõu väljatöötamisest. Mag. iur. Georg Ambach on professor Karl Saarmanni Seltsi juhatuse esimees

Interactions between surface waters in King George Island, Antarctica - a stable isotope perspective

Science.gov (United States)

Perşoiu, Aurel; Bădăluşă, Carmen

2017-04-01

In this paper we present a first study of the isotopic composition of surface waters in the southern peninsulas (Barton, Fildes, Weaver and Potter) of King George Island, Antarctica. We have collected > 200 samples of snow and snowmelt, water (lake, river and spring), ice (glacier ice and permafrost) from the four peninsulas in February 2016 and analyzed them for their oxygen and hydrogen stable isotopic composition. Samples from lake water (50+) indicate a clear west-east depletion trend, suggesting a rain-out process as air masses are moving westward (and are progressively depleted in heavy isotopes) from their origin in the Drake Passage. In both Fildes and Barton Peninsulas, permafrost samples have the heaviest isotopic composition, most probably due to preferential incorporation of heavy isotopes in the ice during freezing (and no fractionation during melting). As permafrost melts, the resulting water mixes with isotopically lighter infiltrated snowmelt, and thus the groundwater has a lower isotopic composition. Further, lake and river (the later fed by lakes) water has the lightest isotopic composition, being derived mostly from the melting of light snow and glacier ice. It seems feasible to separate isotopically water in lakes/rivers (largely fed by melting multi-year glaciers and snow) and water from melting of snow/ground ice This preliminary study suggests that it is possible to separate various water sources in the southern peninsulas of King George Island, and this separation could be used to study permafrost degradation, as well as feeding and migration patterns in the bird fauna, with implications for protection purposes. Acknowledgments. The National Institute of Research and Development for Biological Sciences (Bucharest, Romania) and the Korean polar institute financially supported fieldwork in King George Island. We thank the personal at King Sejong (South Korea), Belingshaussen (Russia) and Carlini (Argentina) stations in King George Island for

George Mandler (1924-2016).

Science.gov (United States)

Craik, Fergus

2017-10-01

Presents an obituary for George Mandler, who died in London on May 6, 2016 at the age of 91. Mandler was one of the pioneers of the cognitive revolution in psychology. He was instrumental in moving the study of human learning from notions based largely on associations to a view of memory as an organized, nested hierarchical structure. Mandler was also a major proponent of the dual-process theory of recognition memory, in which general feelings of familiarity are distinguished from the context-rich experience of recollection. He brought the study of emotion into prominence, suggesting how emotion and cognition are related. Finally, he repatriated the concept of consciousness from its intellectual exile under behaviorism, stating boldly in 1975 that the construct was respectable, useful, and probably necessary. Mandler edited the Psychological Review from 1970 to 1976, chaired the Governing Board of the Psychonomic Society, and was president of APA Divisions 1 (General Psychology) and 3 (Experimental Psychology and Cognitive Science). (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Georges Charpak: 1924-2010

CERN Multimedia

2010-01-01

All of CERN was deeply saddened to learn the news that our friend and colleague, Georges Charpak, passed away on 29 September 2010.   There are few people who can honestly be said to have changed the world, but Charpak was one of them. Born in Dabrovika, Poland on 8 March 1924, Charpak fled the Nazi regime under a false identity and moved to France where he joined the resistance. Arrested and deported to Dachau, he returned to France after the war and took French nationality in 1946. A student of Frédéric Joliot-Curie at the Collège de France, he joined CERN in 1959, just five years after the Organization’s foundation, and he certainly left his mark. From the start, Charpak applied himself to the development of new particle detector techniques. His outstanding and pioneering efforts revolutionised particle physics, taking the field into the electronic age. It is fair to say that without the developments pioneered by him, particularly the invention of t...

The Many Sides of Happy Lim: aka Hom Ah Wing, Lin Jian Fu, Happy Lum, Lin Chien Fu, Hom Yen Chuck, Lam Kin Foo, Lum Kin Foo, Hom, Lim Goon Wing, Lim Gin Foo, Gin Foo Lin, Koon Wing Lim, Henry Chin, Lim Ying Chuck, Lim Ah Wing, et. al.

Directory of Open Access Journals (Sweden)

Gordon H. Chang

2010-03-01

Full Text Available

Known to the FBI, INS, and IRS as Mr. Ah Wing Hom, he was also Lin Jian Fu, Jian Fu (Tough Guy, or just Fu to the readers of the many poems and short stories he published in Chinese over four decades in the twentieth century. And to still others, primarily English-readers of his writing, he was Happy Lim, an ironic, even tragically bizarre name, as his life was far from pleasant. On New Year's Day 1986, he died alone in a dingy San Francisco Chinatown bachelor hotel suffering from a bacterial infection and a chronic blood disorder that had required the amputation of all his toes the year before. He was seventy-eight years of age and had spent most of his life within blocks of where he died.

Plea Bargaining: A Recreation of George Orwell's Animal Farm in ...

African Journals Online (AJOL)

Animal Farm is an allegorical novel by George Orwell in which he depicted social injustice precipitated by the insincerity of leadership and the betrayal of the people by their leaders which has made the novel relevant as the experience depicted therein “seamlessly steps into the realities of everyday life” (Achebe 2012) in ...

The George Wallace Shooting: News Diffusion and the Sleeper Effect.

Science.gov (United States)

Steinfatt, Thomas M.; And Others

Previous studies conclude that the assassination attempt on George C. Wallace was a news event of high, but not maximum, importance, implying that the majority of respondents in any sample would report first learning of the attack via mass media sources. The authors interviewed 144 persons in Ann Arbor, Michigan, regarding their awareness of the…

Vehicles to Belief: Aristotle's Enthymeme and George Campbell's Vivacity Compared.

Science.gov (United States)

Roob, Andy

The central concepts from two rhetorical systems (the enthymeme in Aristotle's rhetoric and vivacity in George Campbell's) may be understood as the connection between speech act and ascension to belief. A review of the literature indicates a gap in the scholarly works seeking to compare and contrast the periods developed by D. Ehninger's systems…

George Berkeley’s criticism to John Locke’s representationalism

Directory of Open Access Journals (Sweden)

Alberto Oya

2018-03-01

Full Text Available In his Treatise concerning the Principles of Human Knowledge, George Berkeley offers some arguments in order to criticize the materialist position. My aim in this paper is to expound and analyze in detail these arguments. Given that Berkeley’s criticism to materialism is, at the end, a criticism to John Locke’s representationalism, I will begin this paper explaining which are the core ideas of Locke’s proposal.

Georges Perec and the avant-garde in the visual arts

DEFF Research Database (Denmark)

Ørum, Tania

2006-01-01

Den franske forfatter Georges Perec tilhører 1960ernes avantgarde, og hans værker deler træk med samtidens billedkunst. Perec deler tresseravantgardens interesse for massekultur, dens kritik af den traditionelle kunstnerrolle og dens ønske om at bevæge sig på tværs af grænserne mellem kunst og li...

Efeito e modo de ação das bacteriocinas produzidas por Lactococcus lactis subsp. lactis ITAL 383, ATCC 11454 e CNRZ 150 contra Listeria innocua LIN 11 Effect and mode of action of the bacterioncin produced by Lactococcus. lactis subsp. lactis ITAL 383, ATCC 11454 e CNRZ 150 against Listeria innocua LIN 11

Directory of Open Access Journals (Sweden)

Izildinha MORENO

1999-01-01

Full Text Available O efeito e o modo de ação das bacteriocinas produzidas por L. lactis subsp. lactis ITAL 383 e CNRZ 150 são similares à nisina de L. lactis subsp. lactis ATCC 11454. Estas bacteriocinas apresentaram um modo de ação bactericida, causando a lise de células de L. innocua LIN 11, associada ao decréscimo da absorbância e da viabilidade celular. O efeito letal foi maior para células em fase exponencial comparativamente à fase estacionária de crescimento. A adsorção dessas bacteriocinas às células de L. innocua LIN 11 foi muito rápida e influenciada pelo pH do meio de suspensão; adsorção máxima foi verificada a pH 6,0 e logo após o contato inicial. Perda completa de adsorção ocorreu em pH 2,0.The effect and mode of action of the bacteriocin produced by L. lactis subsp. lactis ITAL 383 and CNRZ 150 are similar to the nisin produced by L. lactis subsp. lactis ATCC 11454. It was clearly bactericidal, and caused lysis of a strain of L. innocua LIN 11 detected by the decrease of absorbance values and the cell viability. Their lethal effect was considerably higher during the logarithmic growth when compared to the stationary phase. Adsorption developed rapidly and was influenced by the pH value of the suspension medium. Maximum adsorption was observed at pH 6,0 and immediately after initial contact and loss at pH 2,0.

Obstetric patients admitted to the intensive care unit of Dr George ...

African Journals Online (AJOL)

require ICU level of care. S Afr J Crit Care 2017;33(1):12-14. ... at Dr George Mukhari Academic Hospital (DGMAH), Ga-Rankuwa,. SA. DGMAH is a ... day. The median length of ICU stay was 24 hours (range 1 - 17 days). Eighty-seven percent ...

Insurgency and American Foreign Policy: the case of George McGovern

NARCIS (Netherlands)

Haar, Roberta

2017-01-01

As a distinct foreign-policy group, neoconservatives emerged in a period of social unrest and political cynicism—a time when insurgent presidential candidates can have profound effects on the outlook and conduct of foreign policy. The George McGovern insurgency is an important historical event that

RECORDANDO LA ESTRATEGIA DE SEGURIDAD DE GEORGE W.BUSH EN LA ERA DE DONALD TRUMP

Directory of Open Access Journals (Sweden)

Nelson Llanos Sierra

2017-12-01

Full Text Available Este trabajo analiza la estrategia de seguridad del presidente George W. Bush y su posible vinculación con el comportamiento internacional de Donald Trump, ahondando en las similitudes de ambos casos, tanto en sus objetivos como contexto internacional. Sobre la base del accionar de Trump durante los primeros meses de su mandato, este trabajo sugiere que el actual mandatario estadounidense está desarrollando, y consolidará, una estrategia de seguridad sustentada en principios, valores y objetivos comparables a aquellos defendidos por George W. Bush a inicios del presente siglo.

Role of Imaging and Cytogenetics in Evaluation of DiGeorge Syndrome - A Rare Entity in Clinical Practice.

Science.gov (United States)

Ramachandran, Rajoo; Babu, Sellappan Rajamanickam; Ilanchezhian, Subramanian; Radhakrishnan, Prabhu Radhan

2015-01-01

DiGeorge syndrome is a congenital genetic disorder that affects the endocrine system, mainly the thymus and parathyroid glands. The syndrome produces different symptoms, which vary in severity and character between patients. It manifests with craniofacial dysmorphism and defects in the heart, parathyroid, and thymus. Patients can present with a palatal deformity and nasal speech. This rare entity is caused mainly due to deletion of chromosome 22q11.2. Radiographic evaluation of DiGeorge syndrome is necessary to define aberrant anatomy, evaluate central nervous system, craniofacial abnormalities, musculoskeletal system, and cardiothoracic contents. It also helps in planning surgical procedures and surgical reconstructions. We report a case of DiGeorge syndrome in a 4-month-old neonate and discuss the clinical, imaging, and cytogenetic findings that helped in the diagnosis of this rare entity.

Rose George: Deep Sea and Foreign Going: Inside Shipping, the Invisible Industry that Brings you 90% of Everything

DEFF Research Database (Denmark)

Taudal Poulsen, René

2014-01-01

Book review of: Rose George: Deep Sea and Foreign Going: Inside Shipping, the Invisible Industry that Brings you 90% of Everything. London :Portobello Books, 2013. 320 pp. ISBN 9781846272639......Book review of: Rose George: Deep Sea and Foreign Going: Inside Shipping, the Invisible Industry that Brings you 90% of Everything. London :Portobello Books, 2013. 320 pp. ISBN 9781846272639...

George Martin Baer, DVM, MPH, 1936-2009. The father of oral rabies vaccination

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Paul E. Grunenwald, DVM, MSc

2009-09-01

Full Text Available George Martin Baer, known for his development of the oral rabies vaccine instrumental in rabies control in Europe, died on 2 June 2009 at the age of 73 in Mexico City, Mexico. He was born on 12 January 1936 in London, England, to German immigrants who had fled Nazi Germany. His family emigrated to the United States in 1940 where he grew up in New Rochelle, New York.George had a love of animals, particularly horses, which may have influenced his career path. He earned an undergraduate degree in agricultural sciences in 1954 from Cornell University followed by a degree in veterinary medicine in 1959. He then went on to earn a master’s degree in public health in 1960 from the University of Michigan. During some time in Mexico, George met and fell in love with his wife, Maria Olga Lara. Thanks to James H. Steele, his long-time friend and mentor, he started his public health career with the Centers for Disease Control (CDC and was assigned to the New York State Health Department where he learned epidemiology and virology. He went on to work on bat rabies at the CDC’s Southwest Rabies Investigations Laboratory in New Mexico. From 1966 to 1969, he worked with the National Institute for Livestock Research (Instituto Nacional de Investigaciones Pecuarias: INIP in Mexico and helped develop the Plan Derriengue to control paralytic bovine rabies which became the early work in the development of Mexico’s rabies control programmes. He returned to Atlanta in 1969 to direct the CDC Rabies Laboratory. There, he led a team of researchers in developing an oral rabies vaccine for wildlife, earning him the title ‘The Father of Oral Rabies Vaccination’. His text, The Natural History of Rabies, first published in 1975 and again in 1991, continues to be a definitive international reference for rabies control.After his retirement, George returned to Mexico and continued his research and training, working to develop not only public health programmes, but new

Cyberspace: A Selected Bibliography

Science.gov (United States)

2013-05-01

Implications of the Private Sector’s Role in Cyber Conflict." Texas International Law Journal 47, no. 3 (Summer 2012): 617-640. ProQuest Lucas, George R...Cyberspace." Proceedings: United States Naval Institute 137, no. 2 (February 2011): 32-37. ProQuest Lin, Herbert . "Escalation Dynamics and Conflict...Harold Hongju. "International Law in Cyberspace." USCYBERCOM [United States Cyber Command] Inter-Agency Legal Conference, Ft. Meade , MD, September 18

Evidence of cation vacancy induced room temperature ferromagnetism in Li-N codoped ZnO thin films

Science.gov (United States)

Zhang, B. Y.; Yao, B.; Li, Y. F.; Liu, A. M.; Zhang, Z. Z.; Li, B. H.; Xing, G. Z.; Wu, T.; Qin, X. B.; Zhao, D. X.; Shan, C. X.; Shen, D. Z.

2011-10-01

Room temperature ferromagnetism (RTFM) was observed in Li-N codoped ZnO thin films [ZnO:(Li, N)] fabricated by plasma-assisted molecular beam epitaxy, and p-type ZnO:(Li, N) shows the strongest RTFM. Positron annihilation spectroscopy and low temperature photoluminescence measurements indicate that the RTFM in ZnO:(Li, N) is attributed to the defect complex related to VZn, such as VZn and Lii-NO-VZn complex, well supported by first-principles calculations. The incorporation of NO can stabilize and enhance the RTFM of ZnO:(Li, N) by combining with Lii to form Lii-NO complex, which restrains the compensation of Lii for VZn and makes the ZnO:(Li, N) conduct in p-type.

Role of Imaging and Cytogenetics in Evaluation of DiGeorge Syndrome - A Rare Entity in Clinical Practice

Directory of Open Access Journals (Sweden)

Rajoo Ramachandran

2015-01-01

Full Text Available DiGeorge syndrome is a congenital genetic disorder that affects the endocrine system, mainly the thymus and parathyroid glands. The syndrome produces different symptoms, which vary in severity and character between patients. It manifests with craniofacial dysmorphism and defects in the heart, parathyroid, and thymus. Patients can present with a palatal deformity and nasal speech. This rare entity is caused mainly due to deletion of chromosome 22q11.2. Radiographic evaluation of DiGeorge syndrome is necessary to define aberrant anatomy, evaluate central nervous system, craniofacial abnormalities, musculoskeletal system, and cardiothoracic contents. It also helps in planning surgical procedures and surgical reconstructions. We report a case of DiGeorge syndrome in a 4-month-old neonate and discuss the clinical, imaging, and cytogenetic findings that helped in the diagnosis of this rare entity.

Georges Bataille and the Transgression of Taboos by Stephan Dedalus

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Shataw Naseri

2014-07-01

Full Text Available James Joyce's A Portrait of the Artist as a Young Man is not a pornographic novel like Georges Bataille' Story of the Eye; however, the present study attempts to trace Bataille's heterological notions in A Portrait. This paper attempts to see whether or not Stephan Dedalus as the main character of Joyce's literary work, has the potential to carry Batatille's heterogeneous elements which shatter any religious, linguistic, economic and political system. In order to reach this goal, the paper first attempts to establish the powerful dominance of the Catholic discourse, one of the strictest religious systems in the world, over Ireland which is the main setting of A Portrait. In the next part it will trace the authoritarian shadow of Catholicism and its impression upon Stephen Dedalus. Here, the principal aim is to indicate the significance of Stephen's transgressive acts in the novel and to see whether these transgressions have Bataillean nature as they shatter a very strict religious structure. Afterward, Stephen's transgressions as well as the implicit reaction of the religious system toward these transgressions will be investigated regarding Georges Bataille's heterogeneous notions.

From Myth to Reality: Humanities Study at Prince George's Community College.

Science.gov (United States)

Engleberg, Isa N.

In 1989, Prince George's Community College (PGCC) received a grant from the National Endowment for the Humanities to support a 4-week summer seminar in Greek mythology for humanities faculty. The seminar, entitled "The Nature and Function of Greek Mythology," provided enough financial compensation to free the faculty from summer school teaching,…

Aerosols in King George Island (Antarctic peninsula) using PIXE and alpha spectrometry

International Nuclear Information System (INIS)

Dias da Cunha, K.; Medeiros, G.; Leal, M.A.; Lima, C.; Dalia, K.C.

2009-01-01

The aim of this study was to characterize the airborne particles and particles deposited in the recent snow samples collected at King George Island (Admiralty Bay) in order to evaluate the possible local sources of airborne particles and the aerosol transport from South America to Antarctic at sea level. Airborne particles samples were collected using a cascade impactor and cyclones at several sampling points at Admiralty Bay. Airborne particles were also collected during the ship travel from Rio de Janeiro to Antarctica. The recent snow samples and aerosols collected at several sampling points at Admiralty Bay were analyzed by PIXE for the determination of the elemental mass concentration. Snow samples were analyzed by alpha spectrometry to determine the 232Th, 228Th, 238U and 234U concentrations in snow. The Mass Median Aerodynamic Diameter of airborne particles was determined. The results suggest that there is a correlation between the aerosol samples and the particles deposited in the snow, but the elemental mass distributions are not equal. The snow elemental concentration can be used as an indicator of the elements present in the aerosols. The local aerosol sources (natural and anthropogenic) have been considered to characterize the aerosol transport to Antarctic, mainly King George Island. The main aerosol sources are the marine spray, weathering of local rocks and anthropogenic sources, as the diesel burning in the island. Besides the local aerosol sources the transport of airborne particles from south Atlantic to Antarctic is an important source of airborne particles at King George Island. (author)

Raamidest välja mõtlemine pole piisav / Gabor George Burt ; interv. Harli Uljas

Index Scriptorium Estoniae

Burt, Gabor George

2006-01-01

Juhtimisstrateegia Blue Ocean Strategy eestkõneleja Gabor George Burti sõnul tuleb edu saavutamiseks keskenduda kliendile ning tegeleda personaalselt kliendi jaoks sobiva lahenduse loomisega. Kommenteerib Priit Põldoja

Muusika : Viiulivirtuoos Kanadast. Holland Music Sessionsi stipendiaadid. "Jazzkaar" Georg Otsa jälgedes

Index Scriptorium Estoniae

2002-01-01

Estonia kontserdisaalis esineb ERSO ees tippviiuldaja Lara St. John. Holland Music Sessions'i meistrikursustele pääses konkursi korras kuus eesti noort muusikut. Vene Draamateatris 17. III toimuvast kontserdist "Georg Otsa jälgedes"

George Orwell and 1984: a personal view

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ALFREDO SANDOVAL GÓMEZ

2013-11-01

Full Text Available George Orwell´s 1984 is considered a great negative utopia, in the sense it depicts the nightmare of what life might become in an oligarchic collectivism pursued to its logical conclusion. Under a social setup which is nothing but totalitarian barbarism, eternal warfare is the price one pays for an elusive peace. The Party with capital P keeps a total control over all of man´s actions as well as thoughts . The novel is a great satire and it attempts to diagnose man´s alienation in all its aspects, but with special emphasis on the social organization recommended by Marx and practiced by Stalin.  

[Georg Friedrich Nicolai: war physician against war].

Science.gov (United States)

van Bergen, L

2017-01-01

Georg Friedrich Nicolai was a German professor and heart specialist who was one of the few who protested against the war at the beginning of World War I. As a result, he lost his job and was convicted. After the war, right-wing nationalist students and lack of support from his university superiors made it impossible for him to teach. He left Germany in 1922, never to return. In his book, Die Biologie des Krieges (The Biology of War), which was published in neutral Switzerland in 1917, he contradicted the social Darwinist idea - supported by many physicians as well - that war strengthened humanity, people and races, physically and mentally. On the contrary, he argued, war is biologically counterproductive.

Targeting Histone Abnormality in Triple Negative Breast Cancer

Science.gov (United States)

2016-08-01

W81XWH-14-1-0237 Triple-Negative Breast Cancer Davidson, PI U10 CA180844 NCI NCTN-Network Lead 5% 2014- 2019 $11,255 Davidson, Co-PI Academic Site...MD AACR High Tech Strategic Business Meeting, Sunnyvale, CA Medical Oncology Board Review, George Washington University, Washington, DC Great...both ductal car - cinoma in situ and invasive ductal carcinoma of the breast. Oncogene 2003; 22: 2021–2033. 25 Lin T, Ponn A, Hu X, Law BK, Lu J

Environmental conditions of interstadial (MIS 3 and features of the last glacial maximum on the King George island (West Antarctica

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S. R. Verkulich

2013-01-01

Full Text Available The interstadial marine deposits stratum was described in the Fildes Peninsula (King George Island due to field and laboratory investigations during 2008–2011. The stratum fragments occur in the west and north-west parts of peninsula in following forms: sections of soft sediments, containing fossil shells, marine algae, bones of marine animals and rich marine diatom complexes in situ (11 sites; fragments of shells and bones on the surface (25 sites. According to the results of radiocarbon dating, these deposits were accumulated within the period 19–50 ky BP. Geographical and altitude settings of the sites, age characteristics, taxonomy of fossil flora and fauna, and good safety of the soft deposits stratum allow to make following conclusions: during interstadial, sea water covered significant part of King George Island up to the present altitude of 40 m a.s.l., and the King George Island glaciation had smaller size then; environmental conditions for the interstadial deposit stratum accumulation were at least not colder than today; probably, the King George island territory was covered entirely by ice masses of Last glacial maximum not earlier than 19 ky BP; during Last glacial maximum, King George Island was covered by thin, «cold», not mobile glaciers, which contribute to conservation of the soft marine interstadial deposits filled with fossil flora and fauna.

Persia lost : how the foreign policy hawks of the George W. Bush administration blocked rapprochement with Iran

OpenAIRE

Fagernes, Therese

2011-01-01

The presidency of George W. Bush was a period of controversy. The foreign policy that the administration implemented would be criticized both inside of the United States and across the world. The purpose of this thesis is to look at how the senior members of the Bush administration’s foreign policy team influenced the foreign policy process during President George Walker Bush’s first term. It will apply the interaction and bitter opposition between these individuals and the defining events th...

George Jeffreys: Pentecostal and Contemporary Implications

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William K Kay

2018-02-01

Full Text Available The life and work of the Welsh evangelist George Jeffreys resulted in the planting of two denominations in the UK between 1915 and 1962, when he died. The Elim churches continue to this day to be one of the larger classical Pentecostal denominations in the UK, while the Bible Pattern Fellowship dispersed on Jeffreys’ death. The disputes that led to Jeffreys’ departure from Elim were said to have arisen from his adherence to British Israel doctrine, though his supporters believed they arose from his championing of local church ownership and democracy. This paper considers sociological and other reasons for Jeffreys’ remarkable success in the interwar years and his eventual departure from a denomination he founded. It concludes by reflecting on topics (such as the importance of debate and law that have relevance for contemporary Pentecostalism.

Reseña de HYPER-TEXT-THEORY, ed. George Landow.

OpenAIRE

García Landa, José Ángel

2010-01-01

Reseña del libro editado por George P. Landow HYPER/TEXT/THEORY (Baltimore: Johns Hopkins UP, 1994), volumen sobre el impacto del hipertexto en teoría literaria, narratología y escritura experimental. La reseña atiende sobre todo a los desarrollos complementarios a la teoría de Landow que podían vislumbrarse en los primeros años del hipertexto global, la World Wide Web.

Search for the signature of a halo structure in the p(6He,6Li)n reaction

International Nuclear Information System (INIS)

Cortina-Gil, M.D.; Roussel-Chomaz, P.; Mittig, W.; Casandjian, J.M.; Chartier, M.; Alamanos, N.; Auger, F.; Fekou-Youmbi, V.; Blumenfeld, Y.; and others.

1995-01-01

The elastic scattering p( 6 He, 6 He)p and charge exchange reaction p( 6 He, 6 Li)n have been measured in reverse kinematics with a secondary 6 He beam. The angular distributions for these reactions were obtained. In the case of the charge exchange reaction, the ratio of the cross section for the Gamow-Teller transition to the ground state, and for the Fermi transition to the isobaric analog state is a measure of the relative strength of the two components of the exchange interaction. This ratio is found compatible with existing systematics for stable T=1 nuclei, and no clear signature of a halo structure was found in the present data. (author)

Quando "falha a fala" e "fala a bala": lingua(gem e violência em Cidade de Deus, de Paulo Lins

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Rita Gabrielli Pereira

2018-04-01

Full Text Available Cidade de Deus traz em si a história da construção do conjunto habitacional, cujo nome intitula o romance, e de sua transformação em uma das favelas mais violentas do Rio de Janeiro, por meio do entrecruzamento das histórias de Cabeleira, Bené, Zé Pequeno e Busca-Pé. Concebendo o romance, nos atos da escrita e da leitura, como uma enunciação (BENVENISTE, 1989a; 1989b; 1995a; 1995b entre autor e leitor, constituída por outras enunciações — entre narrador e narratário e entre personagens — a partir do "ato ficcional" (ISER, 2002 do autor, vamos nos guiar por essa tessitura de/entre histórias para rastrear o modo como Lins relaciona linguagem e violência. Palavras-chave: Lingua(gem, Subjetividade, Violência ______________________________ Cidade de Deus tells the history of the construction of the housing complex that entitles the novel and its transformation process into one of the most violent slums of Rio de Janeiro. By treating the novel as an enunciation (BENVENISTE, 1989a; 1989b; 1995a; 1995b between author and reader, which is made of other enunciations − between narrator and narratee and between characters −, based on the author´s “fictional act”(ISER, 2002, we intend to analyze the way how Lins relates language and violence. Keywords: Language, Subjectivity, Violence.

The extent and causes of stress in teachers in the George region

African Journals Online (AJOL)

Erna Kinsey

The purpose of this particular research project was to establish which aspects of the teaching profession are stress-related in the. George area. ... for teachers to manage their stress are based on these conclusions. ... Positive (good) stress (for example an opportunity, a promotion, .... school classroom (Hanks, 1990:1213).

Présentation du texte de Georges Balandier « Phénomènes sociaux totaux et dynamique sociale »

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Liliane Voyé

2008-10-01

Full Text Available Introduction et mise en perspective du texte de Georges Balandier « Phénomènes sociaux totaux et dynamique sociale », initialement publié dans les Cahiers Internationaux de Sociologie, volume 30, 1961, pp. 23-34. Reproduit avec l’aimable autorisation des Cahiers Internationaux de Sociologie.Presentation of Georges Balandier’s text « Total social phenomenon and social dynamism »Introduction and contextualization of the Georges Balandier’s article « Phénomènes sociaux totaux et dynamique sociale » first published in the Cahiers Internationaux de Sociologie, volume 30, 1961, pp. 23-34 and reprinted with the kind authorization of the revue.Presentación del trabajo de Georges Balandrier "Hecho social total y dinámica social"Introducción y análisis del texto de Georges Balandrier « Phénomènes sociaux totaux et dynamique sociale », publicado por primera vez en los Cahiers Internationaux de Sociologie, volumen 30, 1961, pp. 23-34. Con la amable autorización de los Cahiers Internationaux de Sociologie.

George Combe and common sense.

Science.gov (United States)

Dyde, Sean

2015-06-01

This article examines the history of two fields of enquiry in late eighteenth- and early nineteenth-century Scotland: the rise and fall of the common sense school of philosophy and phrenology as presented in the works of George Combe. Although many previous historians have construed these histories as separate, indeed sometimes incommensurate, I propose that their paths were intertwined to a greater extent than has previously been given credit. The philosophy of common sense was a response to problems raised by Enlightenment thinkers, particularly David Hume, and spurred a theory of the mind and its mode of study. In order to succeed, or even to be considered a rival of these established understandings, phrenologists adapted their arguments for the sake of engaging in philosophical dispute. I argue that this debate contributed to the relative success of these groups: phrenology as a well-known historical subject, common sense now largely forgotten. Moreover, this history seeks to question the place of phrenology within the sciences of mind in nineteenth-century Britain.

[George Nicholas Papanicolaou].

Science.gov (United States)

Broso, P R; Buffetti, G

1993-10-01

G. N. Papanicolaou was born on May the 13, 1883 in the city of Kymi on the Greek island of Euboea. He received his MD degree from the University of Athens in 1904 and a PhD from the University of Munich in 1910. After service as a medical officer in the Balkan War of 1912-1913, he came to New York with Mary (for over 50 years Dr Pap's life companion). George's violin playing at restaurants and coffee-shops supplied them with a few extra cents. Papanicolaou was appointed assistant in the Pathology Laboratory at the New York Hospital. In 1928 he presented his work "New Cancer Diagnosis" to the third race betterment conference (Battle Creek, Michigan). But the work was met with scepticism. The now famous monograph "The Diagnostic Value of Vaginal Smears in Carcinoma of the Uterus" was published in 1941 in the Am J Obst Gyn. During this time, he developed his method of preservation of these cells by wet fixation and precise staining. Papanicolaou persisted with his ideas, and finally cytologic examination of the cervix was accepted. The power of Papanicolaou screening for uterine cancer was remarkable. The first National Cytology Congress, held in 1948, hailed this new diagnostic tool for carcinoma of the cervix as unique because it could detect cancer before it was visible. He described the importance of a distinct cellular pattern corresponding to cervical intraepithelial neoplastic lesions. The value of this pattern, expressing evolutionary steps in the development of cancer at individual cell levels, was not appreciated.(ABSTRACT TRUNCATED AT 250 WORDS)

Dante deutsch: Riflessioni sulle traduzioni tedesche della ‘Divina Commedia’ nel Novecento (George e Borchardt

Directory of Open Access Journals (Sweden)

Thomas Klinkert

2016-06-01

Full Text Available Malgrado il pregiudizio secondo il quale la poesia in generale e la Divina Commedia in particolare sarebbero intraducibili, quest'ultima dal Settecento in poi è stata tradotta in tedesco – sia parzialmente che completamente – più di centosettanta volte. Non solo i romantici ma anche i filologi dell'Ottocento hanno contribuito in maniera decisiva a questa intensa ricezione. Nel Novecento la pratica della traduzione è stata portata avanti da due grandi poeti: Stefan George e Rudolf Borchardt. Un'analisi selettiva del primo canto dell’Inferno e delle traduzioni di George e Borchardt mostrerà alcune trasformazioni specifiche del testo dantesco a seconda delle scelte linguistiche dei due poeti.

The erudite humility of the historian: the 'critical epistemology' of Georges Lantéri-Laura.

Science.gov (United States)

Basso Lorini, Elisabetta

2017-06-01

This paper analyses the historical and epistemological work of the French psychiatrist Georges Lantéri-Laura (1930-2004) within the context of the French 'tradition' of history and philosophy of sciences, with special reference to Georges Canguilhem and Michel Foucault. After an introduction devoted to a critical survey of the most recent works on the history and historiography of psychiatry in French, the paper outlines Lantéri-Laura's approach by focusing especially on the role played by the methodological concept of 'semiology' as regards the relation between medicine and psychiatry. The last part of the paper draws attention to the relation between the history and philosophy of psychiatry in light of Lantéri-Laura's 'critical epistemology'.

Evidence of cation vacancy induced room temperature ferromagnetism in Li-N codoped ZnO thin films

International Nuclear Information System (INIS)

Zhang, B. Y.; Yao, B.; Li, Y. F.; Xing, G. Z.; Liu, A. M.; Zhang, Z. Z.; Li, B. H.; Zhao, D. X.; Shan, C. X.; Shen, D. Z.; Wu, T.; Qin, X. B.

2011-01-01

Room temperature ferromagnetism (RTFM) was observed in Li-N codoped ZnO thin films [ZnO:(Li, N)] fabricated by plasma-assisted molecular beam epitaxy, and p-type ZnO:(Li, N) shows the strongest RTFM. Positron annihilation spectroscopy and low temperature photoluminescence measurements indicate that the RTFM in ZnO:(Li, N) is attributed to the defect complex related to V Zn , such as V Zn and Li i -N O -V Zn complex, well supported by first-principles calculations. The incorporation of N O can stabilize and enhance the RTFM of ZnO:(Li, N) by combining with Li i to form Li i -N O complex, which restrains the compensation of Li i for V Zn and makes the ZnO:(Li, N) conduct in p-type.

''SMILE'': A Self Magnetically Insulated Transmission LinE adder for the 8-stage RADLAC II accelerator

International Nuclear Information System (INIS)

Mazarakis, M.G.; Poukey, J.W.; Shope, S.L.; Frost, C.A.; Turman, B.N.; Ramirez, J.J.; Prestwich, K.R.; Pankuch, P.J.

1991-01-01

The RADLAC II Self Magnetically Insulated Transmission LinE ''SMILE'' is a coaxial wave guide structure that is composed of two regions: (a) a 9.5-m voltage adder and (b) a 3-m long extension section. The adder section provides for the addition of the input voltages from the individual water-dielectric pulse forming line feeds. The extension section isolates the adder from the magnetically immersed foilless diode electron source load and efficiently transports the pulsed power out from the deionized water tank of the device. The SMILE modification of the RADLAC II accelerator enabled us to produce high quality beams of up to 14 MV, 100 kA. The design and the experimental evaluation of SMILE will be presented and compared with numerical simulation predictions. 12 refs., 9 figs., 1 tab

What Color Is Your Dog? Taking a Cue from Artist George Rodrigue

Science.gov (United States)

Compton, June

2009-01-01

In this article, the author describes a lesson he created for his second-grade classes which was inspired by the children's book, "Why is Blue Dog Blue?", by George Rodrigue. In this lesson, the students make associations between places, food and events to determine the color of their dogs. (Contains 3 resources.)

George Gamow: a most talented and creative scientist

International Nuclear Information System (INIS)

Yang Qingyu

2002-01-01

As one of the most prominent scientists of the 20th century, George Gamow made notable contributions to many fields of science in his life time. In nuclear physics he proposed the well known 'nuclear potential barrier channel effect' and the Gamow-Teller transition probability of beta decay. In cosmology he did his almost to advocate the 'big bang' theory. Through extraordinary intuition he proposed a theory about how genetic codes work in molecular biology, which was later verified by Watson, Crick and Nirenbery. Gamow's unique style of research and his spirit of bringing forth new ideas in interdisciplinary subjects has greatly benefited scientific research

GEORGE HERBERT MEAD'IN SOSYAL AHLAK ANLAYIŞI

OpenAIRE

Mustafa Kınağ

2017-01-01

Klasik Amerikan pragmatistlerinden George Herbert Mead’a göre benlik, ne salt zihinden ibarettir, ne de ontolojik çatallaşmayı içerir. O, bunun yerine sadece analitik bir ayrım olarak benliği (self) özne benlik (I) ve nesne benlik (me) olarak ifade eder. Ancak ne özne benliği nesne benlik olmaksızın, ne de nesne benliği özne benlik olmaksızın düşünebiliriz. Özne benlik, doğrudan deneyimlerimizde kendisini göstermez, eylemin gerçekleşmesinden sonra biliş alanına girer. O, haf...

Un monochrome poétique de Georges Fourest

OpenAIRE

Robert, Laurent

2007-01-01

Cet article propose une lecture du « Pseudo-sonnet que les amateurs de plaisanterie facile proclameront le plus beau du recueil » extrait de La Négresse blonde (1909) de Georges Fourest. La démarche de Fourest est mise en relation à la fois avec celle des peintures «monochroïdales » d’Alphonse Allais et avec celle du « sonnet en yx » de Stéphane Mallarmé. Elle est finalement perçue dans toute son ambiguïté, entre la mise en cause radicale de la poésie et la facétie fin de siècle. Peer revi...

Tetralogy of Fallot associated with deletion in the DiGeorge region of chromosome 22 (22q11)

Energy Technology Data Exchange (ETDEWEB)

D`Angelo, J.A.; Pillers, D.M.; Jett, P.L. [Oregon Health Sciences Univ. Portland, OR (United States)] [and others

1994-09-01

Cardiac conotruncal defects, such as Tetralogy of Fallot (TOF), are associated with DiGeorge syndrome which has been mapped to the q11 region of chromosome 22 and includes abnormalities of neural crest and branchial arch development. Patients with conotruncal defects and velo-cardio-facial syndrome may have defects in the 22q11 region but not show the complete DiGeorge phenotype consisting of cardiac, thymus, and parathyroid abnormalities. We report two neonates with TOF and small deletions in the DiGeorge region of chromosome 22 (46,XX,del(22)(q11.21q11.23) and 46,XY,del(22)(q11.2q11.2)) using both high-resolution cytogenetics and fluorescence in situ hybridization (FISH). The first patient is a female with TOF and a family history of congenital heart disease. The mother has pulmonic stenosis and a right-sided aortic arch, one brother has TOF, and a second brother has a large VSD. The patient had intrauterine growth retardation and had thrombocytopenia due to maternal IgG platelet-directed autoantibody. Lymphocyte populations, both T and B cells, were reduced in number but responded normally to stimulation. The findings were not attributed to a DiGeorge phenotype. Although she had transient neonatal hypocalcemia, her parathyroid hormone level was normal. The patient was not dysmorphic in the newborn period but her mother had features consistent with velo-cardio-facial syndrome. The second patient was a male with TOF who was not dysmorphic and had no other significant clinical findings and no family history of heart disease. Lymphocyte testing did not reveal a specific immunodeficiency. No significant postnatal hypocalcemia was noted. These cases illustrate that there is a wide spectrum of clinical features associated with defects of the 22q11 region. We recommend karyotype analysis, including FISH probes specific to the DiGeorge region, in any patient with conotruncal cardiac defects.

Niche Differentiation and Prey Selectivity among Common Bottlenose Dolphins (Tursiops truncatus Sighted in St. George Sound, Gulf of Mexico

Directory of Open Access Journals (Sweden)

Rachel M. Wilson

2017-07-01

Full Text Available Two groups of common bottlenose dolphins (Tursiops truncatus have been identified within St. George Sound, Florida, USA: high site-fidelity individuals (HSF which are individuals sighted multiple times in the region (i.e., ≥2 months, ≥2 seasons, and ≥2 years, and low site-fidelity individuals (LSF, which are individuals sighted fewer than 2 months, in 2 different seasons among 2 different years. Our goal was to determine whether differences in foraging behaviors were correlated with differences in sighting frequency and overall usage of St. George Sound by the two groups. We used carbon, nitrogen, and sulfur stable isotopes and niche hypervolume metrics to model the foodweb of St. George Sound. Mixing model results indicated that croaker, mojarra, pigfish, pinfish, and silverperch were the most important prey items for dolphins. The hypervolume metrics demonstrate niche partitioning between HSFs and LSFs, with the HSFs relying more heavily on pinfish, pigfish, and mojarra, while the LSFs relied more on silverperch. Plankton, benthic diatoms, seagrass, and epiphytes all contributed to secondary production within St. George Sound. This diversity of source utilization by seagrass-associated consumers supported by a high rate of total production likely sustains high secondary productivity despite the potential for competition in this system. Zooplankton was the most important basal source to the system, followed by seagrass and benthic primary production (as indicated by a sanddollar proxy. The reliance of dolphins on seagrass-dependent prey indicates that alteration of seagrass habitat would significantly impact the dolphin community foraging in St. George Sound and suggests that preservation of seagrass habitat is an important component of an effective management strategy for dolphin populations in the region.

Vanim humanistlik album amicorum Eestis : Alciato "Embleemid" Georg Locameruse reisialbumina / Katre Kaju, Kristi Viiding

Index Scriptorium Estoniae

Kaju, Katre, 1974-

2014-01-01

Varastest reisialbumitest. Georg Locamerusest ja reisialbumi sisseseadmisest. Locameruse reisialbumi raamatuloolistest ja paleograafilistest aspektidest. Reisialbumist kui selektiivse ja idealiseeritud sotsiaalse võrgustiku peegeldajast. Albumi keelelisest ja kirjanduslikust profiilist. Reisialbumi teekonnast Tartu ülikooli raamatukokku. Editeerimispõhimõtetest

Regio- and Enantioselective Sequential Dehalogenation of rac-1,3-Dibromobutane by Haloalkane Dehalogenase LinB.

Science.gov (United States)

Gross, Johannes; Prokop, Zbyněk; Janssen, Dick; Faber, Kurt; Hall, Mélanie

2016-08-03

The hydrolytic dehalogenation of rac-1,3-dibromobutane catalyzed by the haloalkane dehalogenase LinB from Sphingobium japonicum UT26 proceeds in a sequential fashion: initial formation of intermediate haloalcohols followed by a second hydrolytic step to produce the final diol. Detailed investigation of the course of the reaction revealed favored nucleophilic displacement of the sec-halogen in the first hydrolytic event with pronounced R enantioselectivity. The second hydrolysis step proceeded with a regioselectivity switch at the primary position, with preference for the S enantiomer. Because of complex competition between all eight possible reactions, intermediate haloalcohols formed with moderate to good ee ((S)-4-bromobutan-2-ol: up to 87 %). Similarly, (S)-butane-1,3-diol was formed at a maximum ee of 35 % before full hydrolysis furnished the racemic diol product. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

75 FR 80372 - Proposed Amendment of Restricted Areas R-2907A and R-2907B, Lake George, FL; and R-2910...

Science.gov (United States)

2010-12-22

...-1146; Airspace Docket No. 10-ASO-25] Proposed Amendment of Restricted Areas R-2907A and R-2907B, Lake George, FL; and R-2910, Pinecastle, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice... limits of restricted areas R-2907A and R-2907B, Lake George, FL; and restricted area R-2910, Pinecastle...

Comparability of estimating energy rebound effect should be based on uniform mechanism and benchmark: A reply to Du and Lin

International Nuclear Information System (INIS)

Li, Chengyu; Shao, Shuai; Yang, Lili; Yu, Mingliang

2016-01-01

Du and Lin (2015) argued that the estimation model of the economy-wide energy rebound effect proposed by Shao et al. (2014) should be revised and provided an alternative approach, which they considered to be more consistent with the definition of the rebound effect. However, in this comment, we do not find a valid correction or modification to our original model, because their criticism logic does not originate from the corresponding mechanism in Shao et al. (2014), and their estimation formula has a different benchmark with ours. Moreover, their data samples were also different from ours, generating the incomparable results, and there are some irrational results in the comment. Even based on different estimation formulas in the two studies and using the same estimation method and data sample, the comparison results show that the problem of the estimation formula in our previous study which they claimed does not really exist. We argue that this comment is not consistent with the principle of the rebound effect. Actually, their work can be only regarded as proposing an alternative approach for the estimate of the rebound effect. Therefore, their argument is not enough to overturn our previous study. - Highlights: • A reply to Du and Lin (2015), who questioned our previous study, is provided. • Their criticism logic does not originate from our corresponding mechanism. • Their estimation formula has a different benchmark with ours. • Different data samples in the two papers make their results incomparable. • Their argument is not enough to overturn our previous study.

Solving quantum optimal control problems using Clebsch variables and Lin constraints

Science.gov (United States)

Delgado-Téllez, M.; Ibort, A.; Rodríguez de la Peña, T.

2018-01-01

Clebsch variables (and Lin constraints) are applied to the study of a class of optimal control problems for affine-controlled quantum systems. The optimal control problem will be modelled with controls defined on an auxiliary space where the dynamical group of the system acts freely. The reciprocity between both theories: the classical theory defined by the objective functional and the quantum system, is established by using a suitable version of Lagrange’s multipliers theorem and a geometrical interpretation of the constraints of the system as defining a subspace of horizontal curves in an associated bundle. It is shown how the solutions of the variational problem defined by the objective functional determine solutions of the quantum problem. Then a new way of obtaining explicit solutions for a family of optimal control problems for affine-controlled quantum systems (finite or infinite dimensional) is obtained. One of its main advantages, is the the use of Clebsch variables allows to compute such solutions from solutions of invariant problems that can often be computed explicitly. This procedure can be presented as an algorithm that can be applied to a large class of systems. Finally, some simple examples, spin control, a simple quantum Hamiltonian with an ‘Elroy beanie’ type classical model and a controlled one-dimensional quantum harmonic oscillator, illustrating the main features of the theory, will be discussed.

The nineteen theses of Georges Florovsky’s dissertation “The hertsen’s philosophy of history”

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Beiker Matfei

2013-06-01

Full Text Available Paul Gavrilyuk recently reconstructed Georges Florovsky’s dissertation, “Hertsen’s Philosophy of History”, the complete text of which was previously considered lost. According to the report of Alexander Izgoev, G.V. Florovsky presented the summary of his dissertation in 19 theses during his dissertation defense in Prague on 3 June 1923. The typescript of these 19 theses, bearing the title «The Dissertation’s Theses of Privatdozent Georges Florovsky: «The Hertsen’s Philosophy of History»» was recently discovered by Matthew Baker in the Andrew Blane Papers. This document is published here for the first time. The 19 theses support the Gavrilyuk’s hypothesis that the June 1923 redaction of the dissertation consisted of an introduction, three chapters and a conclusion.

George Sand en de Nederlandse negentiende-eeuwse pers. Het belang van computerondersteund tijdschriftonderzoek

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Suzan van Dijk

2010-09-01

Full Text Available  Twentieth-century book and literary historians have tended to seriously underestimate women‟s participation in the nineteenth-century literary field. Thanks to different digital and online tools it becomes now possible to get a better understanding of their presence as authors. This is demonstrated in the present article, where the case „George Sand as received in nineteenth-century Netherlands‟ is used as an example. In particular it is shown that there has been, up to recently, too much reliance on critical articles published in the nineteenth-century literary press. Dutch critics publishing negative comments on George Sand‟s works will most often have had the intention to combat her actual success with Dutch readers and her possible influence on them. And those literary reviews refraining from publishing articles on her work show, by the frequency of their mentioning Sand‟s name, that she was in fact very present in the cultural repertoire of the nineteenth-century Netherlands.

Georges Sagnac: A life for optics

Science.gov (United States)

Darrigol, Olivier

2014-12-01

Georges Sagnac is mostly known for the optical effect in rotating frames that he demonstrated in 1913. His scientific interests were quite diverse: they included photography, optical illusions, X-ray physics, radioactivity, the blue of the sky, anomalous wave propagation, interferometry, strioscopy, and acoustics. An optical theme nonetheless pervaded his entire œuvre. Within optics, an original theory of the propagation of light motivated most of his investigations, from an ingenious explanation of the Fresnel drag, through the discovery of the Sagnac effect, to his quixotic defense of an alternative to relativity theory. Optical analogies efficiently guided his work in other domains. Optics indeed was his true passion. He saw himself as carrying the torch of the two great masters of French optics, Augustin Fresnel and Hippolyte Fizeau. In this mission he overcame his poor health and labored against the modernist tide, with much success originally and bitter isolation in the end. xml:lang="fr"

Ernst Mach, George Sarton and the Empiry of Teaching Science Part I

Science.gov (United States)

Siemsen, Hayo

2012-01-01

George Sarton had a strong influence on modern history of science. The method he pursued throughout his life was the method he had discovered in Ernst Mach's "Mechanics" when he was a student in Ghent. Sarton was in fact throughout his life implementing a research program inspired by the epistemology of Mach. Sarton in turn inspired many…

The new enrichment plant of AREVA, a worthy heir of Georges Besse's industrial visions

International Nuclear Information System (INIS)

Oursel, L.

2011-01-01

The Georges Besse II enrichment plant was inaugurated on December 14., 2010. This plant was the most important investment in France during the last decade, about 3 billion euros. This plant is based on the centrifugation technology instead of the gaseous diffusion that is still in operation in the Georges Besse plant of EURODIF. This plant has been designed in an environment-friendly approach: the centrifugation technology uses 50 times less electricity than gaseous diffusion, does not require taking water from the Rhone river for cooling, does not produce sound nuisances, and the moderate height of the buildings allows a better integration in the environment. The low amount of matter involved in the centrifugation process gives the plant a high level of safety. The plant has a capacity of 7.5 millions UTS with a possible extension to 11 millions UTS. (A.C.)

UF6 overfilling prevention at Eurodif production Georges Besse plant

Energy Technology Data Exchange (ETDEWEB)

Reneaud, J.M. [Eurodif Production, Pierrelatte (France)

1991-12-31

Risk of overfilling exists on different equipments of Georges BESSE Plant: cylinders, desublimers and intermediate tanks. The preventive measures are composed of technical devices: desublimers weighing, load monitoring alarms, automatic controls ... and procedures, training, safety organization. In thirteen years of operation, some incidents have occurred but none of them has caused any personal injuries. They are related and discussed. The main factors involved in the Sequoyah fuel facility accident on 1/4/1986 have been analyzed and taken into account.

Evidence of cation vacancy induced room temperature ferromagnetism in Li-N codoped ZnO thin films

Energy Technology Data Exchange (ETDEWEB)

Zhang, B. Y. [Key Laboratory of Excited State Process, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Science, Changchun 130033 (China); School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116023 (China); Yao, B. [Key Laboratory of Excited State Process, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Science, Changchun 130033 (China); State Key Laboratory of Superhard Material, Department of Physics, Jilin University, Changchun 130023 (China); Li, Y. F.; Xing, G. Z. [State Key Laboratory of Superhard Material, Department of Physics, Jilin University, Changchun 130023 (China); Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore); Liu, A. M. [School of Physics and Optoelectronic Technology, Dalian University of Technology, Dalian 116023 (China); Zhang, Z. Z.; Li, B. H.; Zhao, D. X.; Shan, C. X.; Shen, D. Z. [Key Laboratory of Excited State Process, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Science, Changchun 130033 (China); Wu, T. [Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 (Singapore); Qin, X. B. [Key Laboratory of Nuclear Analysis Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China)

2011-10-31

Room temperature ferromagnetism (RTFM) was observed in Li-N codoped ZnO thin films [ZnO:(Li, N)] fabricated by plasma-assisted molecular beam epitaxy, and p-type ZnO:(Li, N) shows the strongest RTFM. Positron annihilation spectroscopy and low temperature photoluminescence measurements indicate that the RTFM in ZnO:(Li, N) is attributed to the defect complex related to V{sub Zn}, such as V{sub Zn} and Li{sub i}-N{sub O}-V{sub Zn} complex, well supported by first-principles calculations. The incorporation of N{sub O} can stabilize and enhance the RTFM of ZnO:(Li, N) by combining with Li{sub i} to form Li{sub i}-N{sub O} complex, which restrains the compensation of Li{sub i} for V{sub Zn} and makes the ZnO:(Li, N) conduct in p-type.

GS o mirar los cuerpos sociales y emociones desde Georg Simmel

Directory of Open Access Journals (Sweden)

Maya Aguiluz Ibargüen

2005-03-01

Full Text Available El artículo pone de relieve los vínculos existentes entre las claves de Georg Simmel sobre la constitución de lo social y la socialidad respecto a los cambios tecnológicos, arreglos culturales, campos discursivos y estructuras de percepción que se entretejieron alcanzando la vida social de las ciudades europeas y de los circuitos moderno-capitalistas del siglo XIX.

The life and work of George Boole a prelude to the digital age

CERN Document Server

MacHale, Desmond

2014-01-01

This book, aimed at the general reader and now available again, is the first full-length biography of George Boole (1815–1864) who has been variously described as the founder of pure mathematics, one of the fathers of computer science and discoverer of symbolic logic.

Why Students Are Not (Just) Customers (and Other Reflections on Life after George).

Science.gov (United States)

Sharrock, Geoff

2000-01-01

Uses the play "Life after George," involving a dispute between a professor and dean, as a springboard to explore management issues in universities. Discusses students as customers; quality and value in public institutions; funding dilemmas, particularly in the humanities; and university culture versus university management. Advocates moving beyond…

Georges Bank review studies list

International Nuclear Information System (INIS)

1999-01-01

Federal and provincial legislation placed a moratorium on petroleum exploration and drilling on Georges Bank off southwestern Nova Scotia in 1988. Since that time, a public review was conducted to determine the environmental and socio-economic impacts of petroleum exploration on the area. Several consultant groups have been involved and prepared reports for the consideration of the Minister of Natural Resources Canada and the Minister for the Nova Scotia Department of Natural Resources. One of the consultant groups, CEF Consultants Ltd. of Halifax, Nova Scotia conducted a study which resulted in a series of papers on energy and the offshore, dealing with : (1) hydrocarbon resources, (2) exploring for offshore oil and gas, (3) offshore production, storage and transportation, (4) offshore regulation, (5) the energy context, (6) (study not available), (7) the global environmental implications of new hydrocarbon developments, and (8) communities and change. Other studies were conducted by other groups of consultants involving winds, larvae, ecosystems, an economic profile, and a historical overview of offshore and and gas development. The Ministers of Natural Resources Canada and Nova Scotia Department of Natural Resources are required to make a decision regarding the public review and moratorium by January 1, 2000

Cartographie des linéaments géologiques en domaine aride par extraction semi-automatique à partir d’images satellitaires: Exemple à la région d’El Kseïbat (Sahara algérien

Directory of Open Access Journals (Sweden)

Hammad, N.

2016-06-01

Full Text Available Geologists in charge of a detailed lineament mapping in arid and desert area, face the extent of the land and the abundance of eolian deposits. This study presents a semi-automatic approach of extraction of lineament, different from other methods, such as the automatic extraction and manual extraction, by being both fast and objective. It consists of a series of digital processing (textural and spatial filtering, binarization by thresholding and mathematic morphology ... etc. applied to a Landsat 7 ETM+scene. This semi-automatic approach has produced a detailed map of lineaments, while taking account of tectonic directions recognized in the region. It helps mitigate the effect of dune deposits meet the specifications of arid environment. The visual validation of these linear structures, by geoscientists and field data, allowed the identification of the majority of structural lineaments or at least those tried geological.[fr] Les géologues en charge d’une cartographie des linéaments détaillée en domaine aride et désertique, font face à l’étendue des terrains et la présence abondante de dépôts éoliens. La présente étude présente une approche semi-automatique différente des autres méthodes d’extraction des linéaments, à savoir l’extraction automatique et l’extraction manuelle par le fait d’être à la fois rapide et objective. Elle consiste en une succession de traitements numériques (filtrage textural et spatial, binarisation par seuillage et morphologie mathématique…etc. appliqués sur une scène LANDSAT-7 ETM+. Cette approche semi-automatique a permis d’obtenir une carte détaillée des linéaments, tout en tenant compte des directions tectoniques reconnues dans la région. Elle permet d’atténuer l’effet des dépôts dunaires répondant aux spécifications du contexte aride. La validation visuelle de ces structures linéaires, effectuée sur terrain et sur la base de la carte géologique et des données g

Georges Bank drilling moratorium gets extended until 2015

Energy Technology Data Exchange (ETDEWEB)

Anon.

2010-07-15

A moratorium on oil and gas exploration and drilling on the Georges Bank will continue until the end of 2015. Governments require a full public review and research concerning the potential environmental impacts of the project before lifting the moratorium. Canada's federal and provincial governments have agreed to gather information related to the region's fragile ecosystem, and investigate the potential impacts that petroleum-related activities may have in the area. Preliminary reviews are being conducted to study the socio-economic impacts of offshore petroleum activities and to assess new technologies and drilling practices that may be used to reduce the impacts of oil and gas operations. 1 fig.

Georg R. R. Martin: "Jää ja tule laul" filmi ei mahu / intervjueerinud Hendrik Alla

Index Scriptorium Estoniae

Martin, George R. R., 1948-

2011-01-01

USA telekanali HBO telesarjast "Troonide mäng", George R. R. Martini "Jää ja tule laulu" sarja esimese raamatu "Troonide mäng" teleekraniseeringust. Sarja esimene osa esilinastus USA-s 17. aprillil

QUANTUM INSPIRED PARTICLE SWARM COMBINED WITH LIN-KERNIGHAN-HELSGAUN METHOD TO THE TRAVELING SALESMAN PROBLEM

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Bruno Avila Leal de Meirelles Herrera

2015-12-01

Full Text Available ABSTRACT The Traveling Salesman Problem (TSP is one of the most well-known and studied problems of Operations Research field, more specifically, in the Combinatorial Optimization field. As the TSP is a NP (Non-Deterministic Polynomial time-hard problem, there are several heuristic methods which have been proposed for the past decades in the attempt to solve it the best possible way. The aim of this work is to introduce and to evaluate the performance of some approaches for achieving optimal solution considering some symmetrical and asymmetrical TSP instances, which were taken from the Traveling Salesman Problem Library (TSPLIB. The analyzed approaches were divided into three methods: (i Lin-Kernighan-Helsgaun (LKH algorithm; (ii LKH with initial tour based on uniform distribution; and (iii an hybrid proposal combining Particle Swarm Optimization (PSO with quantum inspired behavior and LKH for local search procedure. The tested algorithms presented promising results in terms of computational cost and solution quality.

Cell type-specific recruitment of Drosophila Lin-7 to distinct MAGUK-based protein complexes defines novel roles for Sdt and Dlg-S97.

Science.gov (United States)

Bachmann, André; Timmer, Marco; Sierralta, Jimena; Pietrini, Grazia; Gundelfinger, Eckart D; Knust, Elisabeth; Thomas, Ulrich

2004-04-15

Stardust (Sdt) and Discs-Large (Dlg) are membrane-associated guanylate kinases (MAGUKs) involved in the organization of supramolecular protein complexes at distinct epithelial membrane compartments in Drosophila. Loss of either Sdt or Dlg affects epithelial development with severe effects on apico-basal polarity. Moreover, Dlg is required for the structural and functional integrity of synaptic junctions. Recent biochemical and cell culture studies have revealed that various mammalian MAGUKs can interact with mLin-7/Veli/MALS, a small PDZ-domain protein. To substantiate these findings for their in vivo significance with regard to Sdt- and Dlg-based protein complexes, we analyzed the subcellular distribution of Drosophila Lin-7 (DLin-7) and performed genetic and biochemical assays to characterize its interaction with either of the two MAGUKs. In epithelia, Sdt mediates the recruitment of DLin-7 to the subapical region, while at larval neuromuscular junctions, a particular isoform of Dlg, Dlg-S97, is required for postsynaptic localization of DLin-7. Ectopic expression of Dlg-S97 in epithelia, however, was not sufficient to induce a redistribution of DLin-7. These results imply that the recruitment of DLin-7 to MAGUK-based protein complexes is defined by cell-type specific mechanisms and that DLin-7 acts downstream of Sdt in epithelia and downstream of Dlg at synapses.

'In front of your nose': the existentialism of George Orwell

OpenAIRE

Dulley, Paul Richard

2015-01-01

George Orwell’s reputation as a writer rests largely upon his final two works, selected essays and some of his journalism. As a novelist, he is often considered limited, and it is for this reason that his writing has perhaps received less serious attention than that of many of his contemporaries.\\ud \\ud Some recent publications have sought to redress this balance, identifying an impressive level of artistry, not only in his more recognised works, but in the neglected novels of the 1930s. Yet,...

Como Georg Simmel chegou à modernidade e lhe permaneceu fiel?

Directory of Open Access Journals (Sweden)

Otthein Rammstedt

2015-04-01

Full Text Available How did Georg Simmel, the “first sociologist of modernity” according to David Frisby, get to know and to conceive modernity? We believe that this happened during the phase in which the author participated in Naturalism – a social movement that had a strong impact on German society and culture. We argue that Simmel was strongly influenced by Naturalism, as many aspects of his theoretical and methodological ideas depend directly on the concept of modernity in the sense given to it by Naturalism.

Resonance Fluorescence of a Two-Level Atom Near a Metal Surface. II. Case of a Strong Driving Field,

Science.gov (United States)

1984-02-01

XYH thanks Prof. M. G. Raymer for a useful discussion. REFERENCES 1. X. Y. Huang, J. Lin and T. F. George, J. Chem. Phys., 80, 893 (1984). 2. X. Y...Mollow, Phys. Rev. A, 15, 1023 (1977). 12. J. L. Carlsten, A. Sz6ke and M. G. Raymer , Phys. Rev. A, 15, 1029 (1977). 13. H. Kuhn, J. Chem. Phys. 53, 101...Evanston, Illinois 60201 Austin, Texas 78712 Dr. Robert M. Hexter Dr. R. P. Van Duyne Department of Chemistry Chemistry Department University of Minnesota

Teenindajale tippjuhi omast suurem palk

Index Scriptorium Estoniae

2003-01-01

Marcus Buckingham ja Curt Coffman leiavad oma raamatus "Kõiki reegleid rikkudes", et palgasüsteem peaks arvestama väärtuserinevust erinevate tööde puhul ning soovitavad rakendada nn. laiaskaalalist tasustamist

Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma.

Science.gov (United States)

Wu, Tian-Fu; Li, Yi-Cun; Ma, Si-Rui; Bing-Liu; Zhang, Wen-Feng; Sun, Zhi-Jun

2017-04-01

Tumor necrosis factor receptor-associated factor 1, an adaptor protein of tumor necrosis factor 2, is involved in classical nuclear factor (NF)-κB activation and lymphocyte recruitment. However, less is known about the expression and association of tumor necrosis factor receptor-associated factor 1 with cancer stem cell markers in oral squamous cell carcinoma. This study aimed to investigate the expression of tumor necrosis factor receptor-associated factor 1 and stem cell characteristic markers (lin28 homolog B, B cell-specific Moloney murine leukemia virus integration site 1, and aldehyde dehydrogenase 1) in oral squamous cell carcinoma and analyze their relations. Paraffin-embedded tissues of 78 oral squamous cell carcinomas, 39 normal oral mucosa, and 12 oral dysplasia tissues were employed in tissue microarrays, and the expression of tumor necrosis factor receptor-associated factor 1, B cell-specific Moloney murine leukemia virus integration site 1, aldehyde dehydrogenase 1, and lin28 homolog B was measured by immunohistostaining and digital pathological analysis. The expression of tumor necrosis factor receptor-associated factor 1 was higher in the oral squamous cell carcinoma group as compared with the expression in the oral mucosa (p oral dysplasia (p oral squamous cell carcinoma. The patient survival rate was lower in the highly expressed tumor necrosis factor receptor-associated factor 1 group, although the difference was not significant. The clustering analysis showed that tumor necrosis factor receptor-associated factor 1 was most related to aldehyde dehydrogenase 1. These findings suggest that tumor necrosis factor receptor-associated factor 1 has potential direct/indirect regulations with the cancer stem cell markers in oral squamous cell carcinoma, which may help in further analysis of the cancer stem cell characteristics.

Outside in America: George Michael's music video, public sex and global pop culture

NARCIS (Netherlands)

Kooijman, J.

2004-01-01

Six months after his controversial arrest for ‘lewd conduct’ at a men’s public restroom in Beverly Hills, British pop star George Michael released the song and music video ‘Outside’ which can be seen as an explicit commentary on the controversy. In this article, I read the music video in three ways:

Giving Psychology Away: How George Miller's Vision Is Being Realised by Psychological Literacy

Science.gov (United States)

Banyard, Philip; Hulme, Julie A.

2015-01-01

In George Miller's famous address to the American Psychological Association in 1969 he explored the aims and future direction of psychology. Psychology could develop as a professional elite that develops specialised knowledge that experts can hold on to or it could aim to "give psychology away" and to allow the general public access to…

George Herbert Mead: contributions to history of the social psychology

OpenAIRE

Souza, Renato Ferreira de

2011-01-01

Com este artigo pretende-se contribuir para a compreensão histórica de um autor/personagem da Psicologia. Analisamos e acrescemos conhecimento sobre George Herbert Mead e os desdobramentos de sua teoria psicossocial. Para esse propósito, explicitaremos, no texto, uma das vertentes analíticas utilizadas em nossa dissertação, qual seja: por meio da abordagem social em história da psicologia, confrontamos a vida de Mead com momentos de constituição da psicologia, colocando em relevo aspectos cen...

Monogamy equality in 2⊗2⊗d quantum systems

Science.gov (United States)

Chi, Dong Pyo; Choi, Jeong Woon; Jeong, Kabgyun; San Kim, Jeong; Kim, Taewan; Lee, Soojoon

2008-11-01

There is an interesting property about multipartite entanglement, called the monogamy of entanglement. The property can be shown by the monogamy inequality, called the Coffman-Kundu-Wootters inequality [Phys. Rev. A 61, 052306 (2000); Coffman-Kundu-WoottersPhys. Rev. Lett. 96, 220503 (2006)], and more explicitly by the monogamy equality in terms of the concurrence and the concurrence of assistance, CA(BC)2=CAB2+(CACa)2, in the three-qubit system. In this paper, we consider the monogamy equality in 2⊗2⊗d quantum systems. We show that CA(BC)=CAB if and only if CACa=0 and also show that if CA(BC)=CACa, then CAB=0, while there exists a state in a 2⊗2⊗d system such that CAB=0 but CA(BC)>CACa.

George Herbert Mead on consciousness: antidote to Cartesian absurdities?

DEFF Research Database (Denmark)

Willert, Søren

The article explicates George Herbert Mead's theory of consciousness as presented in Mind, Self and Society. According to Mead, the term consciousness may refer to three different sets of phenomena: (1) the environment as implied by our goal-directed action; Mead names this consciousness aspect...... experience; it is shared by humans and subhuman animals alike; (2) consciousness of environmental experience; Mead names this consciousness aspect awareness; it is exclusively human; (3) the peculiar sensed qualities attaching to consciousness, equalling what is today named qualia. Descartes......-inspired psychology makes the third consciousness aspect all-important. Within Mead's framework for a darwinistically inspired psycholgy, it becomes theoretically insignificant....

The atom of the universe the life and work of Georges Lemaître

CERN Document Server

Lambert, Dominique

2015-01-01

This biography takes readers from the early childhood to the last days of Georges Lemaitre, the man behind the theory of the primeval atom, now better known as the Big Bang theory. But, who was Georges Lemaitre? He was a clergyman, a genius astronomer, an audacious cosmologist, a computer enthusiast ahead of his time, a professor with his head in the clouds, a bon vivant mathematician, and a gourmand. The book peels away these layers, chapter by chapter, from the adventures of a boy from Charleroi (Belgium), who became Monseigneur Lemaitre and influenced contemporary cosmology. The Atom of the Universe follows Lemaitre's works through the course of his life, discovering along the way his involvement with the Chinese student community, his complex relationship with the Vatican, his deep devotion to the University of Louvain, his friendship with figures such as Einstein and Eddington, his adventures through both World Wars, his travels in America, his curious interest in Moliere, and his deep faith lived throug...

George Smoot talks to the Bulletin

CERN Multimedia

CERN Bulletin

2011-01-01

Antimatter, dark matter, dark energy, the nature of space and time… The Nobel Laureate George Smoot answers Paola Catapano’s questions about his career and the many issues about the Universe that are still open.   You started your scientific career as a particle physicist, but soon you moved to astrophysics and in particular the Big Bang theory and cosmology. What motivated your interest in the Big Bang theory? After I graduated from MIT, I went to Berkeley to work with particle physicist Luis Alvarez. He knew I was interested in many areas and said, “tell me what you would like to do and we’ll try and work on that”. I saw astrophysics as a new field, with a lot of new and exciting opportunities. I started doing experiments looking for antimatter, which eventually led to the idea of ASTROMAG and later to AMS. Studying antimatter, we found that it was in less than one part in 10,000. I thought: “There’s no antimatter around us ...

An Analysis of Engagement of Those Who Telecommute vs Those Who Do Not

National Research Council Canada - National Science Library

Boeh, Daniel

2003-01-01

.... The public sector, however, has been slow to implement telecommuting programs. Buckingham and Coffman of the Gallup Organization have done extensive research into what they call "engagement," and as to what comprises an engaged employee...

Exploring Gumaa as an indispensable psycho-social method of ...

African Journals Online (AJOL)

It has to be borne in mind, however, that the term gumaa carries multiple meanings ... nagaa (peace) transcends short-lived conflict management. Nagaa ..... Conference held at the University of Minnesota Coffman Memorial Union Great Hall.

Georges Lemaître: Science and Religion

Science.gov (United States)

Coyne, George V.

In order to appreciate the contribution which Georges Lemaître made to the relationship between religion and science it is necessary to understand how the Catholic Church, of which he was a priest, passed in the course of three centuries, from a position of conflict with the sciences to one of compatible openness and dialogue. In doing this I hope to show that the natural sciences have played a significant role in helping to establish the kind of dialogue that is absolutely necessary for the enrichment of the multifaceted aspects of human culture. I will speak of the following four periods of history: (l) the rise of modern atheism in the seventeenth and eighteenth centuries; (2) anticlericalism in Europe in the nineteenth century; (3) the awakening within the Catholic Church to modern science in the first six decades of the twentieth century; (4) the Church's view today.

An Extension of the Lin-Kernighan-Helsgaun TSP Solver for Constrained Traveling Salesman and Vehicle Routing Problems

DEFF Research Database (Denmark)

Helsgaun, Keld

This report describes the implementation of an extension of the Lin-Kernighan-Helsgaun TSP solver for solving constrained traveling salesman and vehicle routing problems. The extension, which is called LKH-3, is able to solve a variety of well-known problems, including the sequential ordering...... problem (SOP), the traveling repairman problem (TRP), variants of the multiple travel-ing salesman problem (mTSP), as well as vehicle routing problems (VRPs) with capacity, time windows, pickup-and-delivery and distance constraints. The implementation of LKH-3 builds on the idea of transforming...... the problems into standard symmetric traveling salesman problems and handling constraints by means of penalty functions. Extensive testing on benchmark instances from the literature has shown that LKH-3 is effective. Best known solutions are often obtained, and in some cases, new best solutions are found...

Brief history of arrhythmia in the WPW syndrome - the contribution of George Ralph Mines

NARCIS (Netherlands)

Boukens, Bas J.; Janse, Michiel J.

2013-01-01

George Ralph Mines studied the basic principles of reentry and published his data in The Journal of Physiology in 1913. Exactly 100 years later we discuss his first electrophysiological experiments and how his results lead to the insight that was the basis for the treatment of the clinical

Hans-Georg Gadamer’s philosophical hermeneutics: Concepts of reading, understanding and interpretation

OpenAIRE

Paul Regan

2012-01-01

Hans-Georg Gadamer’s philosophical hermeneutics is a popular qualitative research interpretive method aiming to explore the meaning of individual experiences in relation to understanding human interpretation. Gadamer identifies that authentic engagement with reading requires awareness of the inter-subjective nature of understanding in order to promote a reflective engagement with the text. The main concepts of Gadamer’s view of reading and understanding are explored in this paper in relation ...

Surface and Bottom Boundar Layer Dynamics on a Shallow Submarine Bank: Southern Flank of Georges Bank

National Research Council Canada - National Science Library

Werner, Sandra

1999-01-01

The thesis investigates the circulation at a 75-meter deep study site on the southern flank of Georges Bank, a shallow submarine bank located between the deeper Gulf of Maine and the continental slope...

The Nobody: Exploring Archaeological Identity with George Horsfield (1882–1956

Directory of Open Access Journals (Sweden)

Amara Thornton

2014-10-01

Full Text Available This article examines George Horsfield’s life and professional career in the Department of Antiquities in British Mandate Transjordan through his correspondence and images in the archives of UCL Institute of Archaeology. Through these documents, Horsfield’s multiple archaeological identities – architect, official and foreigner – are revealed. His experience, situated within the context of life in British Mandate Transjordan, is used to analyse the archaeologist within a wider history of antiquities departments in British imperial possessions.

Bart's familiar quotations: the enduring biological wisdom of George A. Bartholomew.

Science.gov (United States)

Huey, Raymond B; Bennett, Albert F

2008-01-01

George A. Bartholomew was one of the most influential organismal biologists of the twentieth century. His insights and research were fundamental to the establishment and growth of physiological ecology and evolutionary physiology. In the process of fostering that area of science, he created a body of literature that is striking in the clarity of its thought and presentation. Here we present some of his most insightful and important quotations, group them thematically, and comment on their original context and their continuing relevance.

Georges Lemaître Life, Science and Legacy

CERN Document Server

Mitton, Simon

2012-01-01

The year 2011 marked the 80th anniversary of Georges Lemaître’s primeval atom model of the universe, forerunner of the modern day Big Bang theory. Prompted by this momentous anniversary the Royal Astronomical Society decided to publish a volume of essays on the life, work and faith of this great cosmologist, who was also a Roman Catholic priest. The papers presented in this book examine in detail the historical, cosmological, philosophical and theological issues surrounding the development of the Big Bang theory from its beginnings in the pioneering work of Lemaître through to the modern day. This book offers the best account in English of Lemaître’s life and work. It will be appreciated by professionals and graduate students interested in the history of cosmology.

Comment on "Does the fall phytoplankton blooom control recruitment of Georges Bank, haddock, Melanogrammus aeglefinus, through parental condition?"

DEFF Research Database (Denmark)

Payne, Mark; Dickey-Collas, Mark; Nash, Richard D.M.

2009-01-01

In the paper "Does the fall phytoplankton bloom control recruitment of Georges Bank haddock, Melanogrammus aeglefinus, through parental condition?", Friedland et al. (Can. J. Fish. Aquat. Sci. 65(6): 1076-1086, 2008) examine a sizable number of hypotheses aiming to explain the recruitment patterns...... observed in Georges Bank haddock. The authors focus on a correlation between the size of the autumnal phytoplankton bloom and the survivor ratio (recruitment), concluding this to be the main factor determining recruitment, via the mechanism of adult condition at the time of spawning. Here we examine......, and that in performing the analysis in the chosen manner, Friedland et al. have overlooked alternative hypotheses....

Formation of positive cluster ions Li(n) Br (n = 2-7) and ionization energies studied by thermal ionization mass spectrometry.

Science.gov (United States)

Veličković, S R; Đustebek, J B; Veljković, F M; Veljković, M V

2012-05-01

Clusters of the type Li(n)X (X = halides) can be considered as potential building blocks of cluster-assembly materials. In this work, Li(n)Br (n = 2-7) clusters were obtained by a thermal ionization source of modified design and selected by a magnetic sector mass spectrometer. Positive ions of the Li(n)Br (n = 4-7) cluster were detected for the first time. The order of ion intensities was Li(2)Br(+) > Li(4)Br(+) > Li(5)Br(+) > Li(6)Br(+) > Li(3)Br(+). The ionization energies (IEs) were measured and found to be 3.95 ± 0.20 eV for Li(2)Br, 3.92 ± 0.20 eV for Li(3)Br, 3.93 ± 0.20 eV for Li(4)Br, 4.08 ± 0.20 eV for Li(5)Br, 4.14 ± 0.20 eV for Li(6)Br and 4.19 ± 0.20 eV for Li(7)Br. All of these clusters have a much lower ionization potential than that of the lithium atom, so they belong to the superalkali class. The IEs of Li(n)Br (n = 2-4) are slightly lower than those in the corresponding small Li(n) or Li(n)H clusters, whereas the IEs of Li(n)Br are very similar to those of Li(n) or Li(n)H for n = 5 and 6. The thermal ionization source of modified design is an important means for simultaneously obtaining and measuring the IEs of Li(n)Br (n = 2-7) clusters (because their ions are hermodynamically stable with respect to the loss of lithium atoms in the gas phase) and increasingly contributes toward the development of clusters for practical applications. Copyright © 2012 John Wiley & Sons, Ltd.

STRATEGI PEMECAHAN MASALAH MATEMATIS VERSI GEORGE POLYA DAN PENERAPANNYA DALAM PEMBELAJARAN MATEMATIKA

Directory of Open Access Journals (Sweden)

Wahid Umar

2016-05-01

Full Text Available George Polya telah meletakan suatu warisan “pentingnya mengajar dengan pemecahan masalah”. Setiap masalah memiliki “sepuluh strategi” yang tepat dengan “empat” langkah pemecahan sesuai dengan aspek-aspek dan sudut pandangnya masing-masing di dalam menyelesaikan suatu masalah matematis. Topik ini telah menjadi komponen utama dalam kurikulum matematika pada semua tingkatan pendidikan. NCTM dalam standards (1989 mempublikasikan ”The Curriculum and Evaluations Standards for School Mathematics”, yang menekankan bahwa pemecahan masalah harus menjadi fokus dalam kurikulum matematika di sekolah. Ini berarti bahwa pemecahan masalah merupakan salah satu topik yang sangat penting dalam pembelajaran matematika. Tujuan mengajarkan matematika dengan pemecahan masalah adalah: (1 membantu guru memperbaiki keterampilan pemecahan masalah diri sendiri; (2 diberikan kepada guru untuk membantu siswa mengembangkan keterampilan pemecahan masalah mereka; (3 untuk menyelidiki strategi umum pemecahan masalah; dan (4 bagaimana membuat kata “masalah” dan “pemecahan masalah” menantang dan menarik untuk siswa. Pentingnya para siswa mengalami proses pembelajaran matematika dengan pemecahan masalah matematis. Siswa perlu dipersiapkan dan didorong untuk berpikir bahwa sesuatu itu multi-dimensi sehingga mereka dapat melihat banyak kemungkinan penyelesaian untuk suatu masalah. Dengan demikian, pemecahan masalah matematis dalam pembelajaran matematika merupakan bagian integral dari semua aktivitas matematis. Fokus kajian makalah ini adalah bagaimana strategi pemecahan masalah matematis versi George Polya dan penerapannya dalam pembelajaran matematika.

Lin's theory of flux and nuclear reactions

International Nuclear Information System (INIS)

Ping-Wha Lin

2002-01-01

Mathematical development of Lin's theory of flux is presented. Based on the Theory, when a chemical reaction system is subjected to a high time rate of temperature change, it changes from equilibrium to non-equilibrium conditions. It is proved mathematically that, when a gas system is subjected to a high time rate of temperature increase, the activities of particles (molecules, atoms or nuclei, and electrons) are increased: the particles are accelerated; frequencies and amplitudes of electron and atomic vibrations in a molecule increased; average kinetic energy of the particles increased; atomic bonds are ruptured; electrons are caused to leave their orbits. If most or all of the electrons leave their orbits, the gas fluid becomes plasma, which is very active chemically. The acceleration of nuclei in the dynamic condition can lead to nuclear reactions. In the pilot plant studies conducted at Research Triangle, NC, USA, for SO 2 conversion to SO 3 by rapid heating, a 10-ft high vertically fired combustor (VFC) was used. Air containing 0.5% SO 2 is forced continuously through the VFC, where it is heated by burners for conversion of SO 2 to SO 3 . During the idle period of operation, no external heat is added to the system by turning off the burners. It is observed that, as the air passing through the VFC during the idle period of sixteen hours, the temperature of the flowing air consistently rises up rapidly from ambient temperature (90 deg F) at inlet of the VFC to an average temperature as high as 582 deg F (in the range of 840 deg F to 455 deg F) at one section of the VFC, an increase of about 500 deg F. The air flow temperature increase of such large magnitude and long duration clearly indicates that nuclear reactions are present in VFC. It is also found that the water vapour in the air stream has completely disappeared in the VFC, for no sulphuric acid formation resulting from the reaction of water and SO 3 is detected there. Presumably, the water vapour in the

The botanical activities of George Edward Post (1838-1909).

Science.gov (United States)

Musselman, Lytton John

2006-01-01

George Edward Post wrote the first flora of the Middle East in English. His other botanical activities are less familiar. In addition to the flora, this paper discusses his teaching, fieldwork, contribution to Bible dictionaries, relations with the Boissier Herbarium in Geneva, establishment of the herbarium, and letters. Those letters are used here for the first time. Post corresponded with botanical luminaries of his day including Autran, Baker, Balfour, Barbey, Boissier, Bornmüller, Carruthers, Denslow, Haussknecht, Hooker, Schweinfurth, Thistleton-Dyer, Torrey, and Winkler. His long-term relationship with the herbarium at Geneva is highlighted. In addition, some of the lesser understood aspects of his life including chaplaincy during the American Civil War, and missionary to Syria are discussed.

Family Life and Human Development (Sex Education): The Prince George's County Public Schools Experience.

Science.gov (United States)

Schaffer, Michael J.

1981-01-01

The Prince George's County schools' sex education program for grades K-12 was developed and implemented in the late 1960s and has three focus areas: family life and interpersonal relationships; the physiological and personality changes during puberty; and advanced physiology and psychology of human sexual behavior. The program augments what the…

Teaching a Classic for All Ages: Fairy Tales and Stories of George MacDonald.

Science.gov (United States)

Sadler, Glenn Edward

1995-01-01

Discusses the life and writings of George MacDonald (1824-1905). Suggests that the most striking feature of MacDonald's children's books is his sensitivity toward spiritual values and the power of change within the lives of his characters. Appends a list of questions to stimulate student response to MacDonald's writings. (RS)

Functional comparison of the nematode Hox gene lin-39 in C. elegans and P. pacificus reveals evolutionary conservation of protein function despite divergence of primary sequences

OpenAIRE

Grandien, Kaj; Sommer, Ralf J.

2001-01-01

Hox transcription factors have been implicated in playing a central role in the evolution of animal morphology. Many studies indicate the evolutionary importance of regulatory changes in Hox genes, but little is known about the role of functional changes in Hox proteins. In the nematodes Pristionchus pacificus and Caenorhabditis elegans, developmental processes can be compared at the cellular, genetic, and molecular levels and differences in gene function can be identified. The Hox gene lin-3...

Surficial geology and shaded seafloor relief of Georges Bank, Fundian Channel and Northeast Channel, Gulf of Maine

Science.gov (United States)

Todd, B.J.; Valentine, Page C.

2015-01-01

Georges Bank is a shallow submarine bank that lies south of Nova Scotia and east of Cape Cod and bounds the seaward side of the Gulf of Maine. The international boundary between Canada and the United States transects the bank, and the eastern part of the bank (~7500 square kilometres) lies in Canadian territory. This map shows the surficial geology of a part of Georges Bank at a scale of 1:50 000. This map has companion topographic and backscatter strength maps. These companion maps provide a basis for interpreting the origin of seafloor features and the nature of materials that form the seafloor. The maps are based on multibeam-sonar surveys conducted in 1999 and 2000 to map 11,965 square kilometres of the seafloor.

Digital cultural heritage and its applications: case studies of Digital Mogao Grottos and Chi Lin Nunnery reconstruction

Science.gov (United States)

Li, Deren; Du, Zhiqiang; Zhu, Yixuan; Wang, Tingsong

2010-11-01

Considerable damage has been done to the cultural heritage sites around the world ranging from natural erosion to artificial destruction. With the development of information sciences, frontier technologies are actively introduced to help protect cultural heritage sites. The new concept of a Digital Cultural Heritage has been presented for culture protection and is gradually becoming an efficient method to solve or to remit various difficult problems. This paper puts forward a digitalization method for cultural heritage sites which rationally integrates and utilizes multiform surveying measurements. These techniques have been successfully implemented into two projects, namely the Digital Mogao Grottos and the Chi Lin Nunnery reconstruction. Our results prove that the concept of and the techniques utilized in Digital Cultural Heritage can not only contribute to research, preservation, management, interpretation, and representation of cultural heritages but can also help resolve the conflicts between tourism and protection.

Surface energy balance and turbulence measurements on Warszawa Icefield, King George Island, West Antarctica

Science.gov (United States)

Falk, U.; Sala, H.; Braun, M.

2012-12-01

The Antarctic Peninsula is amongst the fastest warming places on Earth and further temperature increase is to be expected. It has undergone rapid environmental changes in the past decades. Exceptional rates of surface air temperature increases (2.5K in 50 years) are concurrent with retreating glacier fronts, an increase in melt areas, surface lowering and rapid retreat of glaciers, break-up and disintegration of ice shelves. The South Shetland Islands are located on the northern tip of the Antarctic Peninsula and are especially vulnerable to climate change due to their maritime climate. For King George Island we have compiled a unique data set comprising direct measurements of evaporation and sensible heat flux by eddy covariance on the Warszawa Icefield over 1.5 years from November 2010 to 2012 in combination with a fully equipped automated weather station measuring long- and short-wave radiation components, profiles of temperature, humidity and wind velocities as well as glacier ice temperatures. The combination with the eddy covariance data allows for analysis of variability and seasonality of surface energy balance components on a glacier for one and a half years. Repeat measurements of snow accumulation and surface lowering along transects on the glacier and at different locations on King George Island are used for analysis of multi-sensor satellite data to identify melt patterns and bare ice areas during summer within the source area of the ground measurements. In combination with long-term time series of weather data, these data give indication of the sensitivity of the ice cap to the ongoing changes. This research is part of the ESF project IMCOAST funded by BMBF. Field work was carried out at the Dallmann laboratory (Carlini station, King George Island/Isla 25 de Mayo) in cooperation of the Instituto Antartico Argentino (Argentina) and the Alfred-Wegener Institute of Marine and Polar Research (Germany).

Striding Out in the Opposite Direction: The Journalism Career of George Samuel Schuyler, Iconoclast.

Science.gov (United States)

Fleener, Nickieann

Written in a biographical framework, an overview of George Samuel Schuyler's life and his career in journalism is presented in this paper. The preparation that Schuyler had for his career, the positions within journalism he held, and the major writing projects he undertook are discussed. The question of whether there is anything unique or…

Construction of a Creative and Self-Transcending Life: George Sudarshan's Conception and Experience of Creativity

Science.gov (United States)

Raina, Maharaj

2013-01-01

This article presents a philosophical perspective on creativity as described in the writings of George Sudarshan, a highly accomplished theoretical physicist and natural philosopher whose vision of creativity was influenced by "the direct experience of transcendence." The article reviews his conceptualization of the various mental states…

Health Policy Responsiveness: Lessons Learned from Maryland and Prince George's County.

Science.gov (United States)

Sogie-Thomas, Byron; Sankofa, John; Reed, Crystal; Mfume, Kweisi; Doamekpor, Lauren Abla

2018-04-01

Effective, timely, and intentional policy efforts can significantly impact and improve the public's health and reduce racial and ethnic health disparities across the nation. Creating and implementing responsive policies at the state and county level is essential to supporting community efforts to improve health behaviors and health outcomes, particularly for communities of color who bear the brunt of disease risk and negative health outcomes. Using policy examples from the State of Maryland and Prince George's County, the largest and wealthiest predominately African-American county in the USA, this case study highlights the importance of state and county policy action when presented with opportunities to affect long-lasting, positive change. We examine each jurisdiction's policy response through the lens of timeliness, intentionality, and effectiveness. At first glance, it would appear that Maryland responded effectively to the rise in tobacco use. Similarly, at face value, it appears that Prince George's County's unchecked rise in obesity rates among African-Americans is an example of nonresponsiveness among local policymakers in the face of an obesity epidemic. However-guided by a more nuanced understanding of "policy responsiveness"-this analysis uncovers a more revealing picture, with important strengths and limitations seen in both policy situations. This analysis raises critical questions about the determinants of jurisdictions' health policy capacity and how policymakers might best be supported in their efforts to build an arsenal of health policies that are timely, effective, and intentional in meeting the needs of vulnerable communities.

O itinerário da antropologia urbana do ponto de vista da jornada de um autor: uma conversa com Ruben George Oliven

Directory of Open Access Journals (Sweden)

Ana Luiza Carvalho da Rocha

2000-06-01

Full Text Available Entrevista com o Prof. Dr. Ruben George Oliven, Coordenador do PPGAS/UFRGS, a respeito de sua trajetória acadêmica e produção intelectual no âmbito da antropologia urbana.Interview with Prof. Ruben George Oliven, Ph.D, Chair of the Graduate Program in Social Anthropology of the Federal University of Rio Grande do Sul, about his academic career and his studies and publications on urban anthropology.

A fenomenologia revelada: Georges Bataille e a alteração da sociologia

OpenAIRE

Joron, Philippe

2010-01-01

Nesse artigo propomos refletir sobre à fenomenologia batailleana propriamente dita, ou seja, trabalhar na sua distinção da sociologia convencional ou ortodoxa. O objetivo é contribuir na construção de uma história das ideias sociológicas que permitam, pela obra de Georges Bataille, preencher algumas das lacunas de definição derivadas da ciência durkheimiana.

Remarks by president Bush and Estonian president Ilves, november 28, 2006 / Toomas Hendrik Ilves, George W. Bush

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2007-01-01

USA presidendi George W. Bushi ja Eesti presidendi Toomas Hendrik Ilvese kohtumisest Tallinnas 28. novembril 2006. Riigipead keskendusid oma vestluses ühisele tegevusele demokraatia edendamiseks, olukorrale Afganistanis ja Iraagis, viisavabadusele ning olukorrale Gruusias

Reseña de HYPER-TEXT-THEORY (ed. George P. Landow)

OpenAIRE

García Landa, José Ángel

2009-01-01

Reseña del volumen colectivo HYPER-TEXT-THEORY, editado por George P. Landow (Baltimore: Johns Hopkins UP, 1994). Reúne una serie de estudios que reflexionan sobre el concepto de hipertexto, de texto electrónico, y de las redes de textos conectadas por enlaces y comandos cibernéticos, atendiendo ante todo a sus implicaciones para la teoría de la literatura, desde el punto de vista de la narratología y de la hermenéutica postestructuralista. La reseña atiende ante todo a los desarrollos ulteri...

Bush lubas tõstatada viisavabaduse teema / George W. Bush, Toomas Hendrik Ilves ; interv. Ingvar Bärenklau

Index Scriptorium Estoniae

Bush, George W., 1946-

2006-01-01

Ilmunud ka: Postimees : na russkom jazõke, Põhjarannik, Severnoje Poberezhje 29. nov. lk. 3,2,2. USA presidendi George W. Bushi ja Eesti presidendi Toomas Hendrik Ilvese vastused ajakirjanike küsimustele Eesti Panga Iseseisvussaalis toimunud pressikonverentsil 28. novembril 2006

Lichen flora around the Korean Antarctic Scientific Station, King George Island, Antarctic.

Science.gov (United States)

Kim, Ji Hee; Ahn, In-Young; Hong, Soon Gyu; Andreev, Mikhail; Lim, Kwang-Mi; Oh, Mi Jin; Koh, Young Jin; Hur, Jae-Seoun

2006-10-01

As part of the long-term monitoring projects on Antarctic terrestrial vegetation in relation to global climate change, a lichen floristical survey was conducted around the Korean Antarctic Station (King Sejong Station), which is located on Barton Peninsula, King George Island, in January and February of 2006. Two hundred and twenty-five lichen specimens were collected and sixty-two lichen species in 38 genera were identified by morphological characteristics, chemical constituents, TLC analysis and ITS nucleotide sequence analysis.

Density variation of 137Cs activity in surface soil from the King George Island

International Nuclear Information System (INIS)

Osores, Jose; Gonzales, Susana

2013-01-01

The behavior of radiocaesium from the nuclear tests conducted in the southern hemisphere was evaluated and their behavior was estimated on the floor of King George Island. Based on the findings made by several authors, the time of semi-exhaustion for Cs-137 was estimated at 4.5 years accumulated in the region since 1993. (authors).

Os lugares do vazio: impressões antagônigas nos espaços de Georges Perec e Yves Klein

Directory of Open Access Journals (Sweden)

Manlio de Medeiros Speranzini

2013-12-01

Full Text Available Este trabalho toma o livro Un homme qui dort, de Georges Perec, e o texto “La spécialisation de la sensibilité à l’état matière première en sensibilité picturale stabilisée”, do artista Yves Klein, para explorar as maneiras como esses autores, um pela escrita e o outro pela intervenção em uma galeria de arte, sensibilizam os espaços para revelar o vazio. As ideias de Georges Didi-Huberman, presentes no livro O que vemos, o que nos olha, servem para esclarecer a natureza antagônica do vazio que as duas obras suscitam.

George Kelly: cognitive psychologist, humanistic psychologist, or something else entirely?

Science.gov (United States)

Benjafield, John G

2008-11-01

George Kelly was regarded by some of his contemporaries as a cognitive psychologist and by others as a humanistic psychologist. Kelly himself resisted being rubricized. He did, however, name several people who had been influential in his life and work, one of whom was J.F. Herbart. A comparison of Herbart and Kelly reveals several similarities. Both shared a belief that psychology was fundamentally a mathematical discipline. Both eliminated distinctions usually taken for granted in psychology, such as emotion versus cognition. Reconstructing Kelly's relation to Herbart allows one to see more clearly why Kelly was such a unique figure in 20th century psychology.

George Herbert Mead: contribuições para a história da psicologia social George Herbert Mead: contributions to history of the social psychology

Directory of Open Access Journals (Sweden)

Renato Ferreira de Souza

2011-08-01

Full Text Available Com este artigo pretende-se contribuir para a compreensão histórica de um autor/personagem da Psicologia. Analisamos e acrescemos conhecimento sobre George Herbert Mead e os desdobramentos de sua teoria psicossocial. Para esse propósito, explicitaremos, no texto, uma das vertentes analíticas utilizadas em nossa dissertação, qual seja: por meio da abordagem social em história da psicologia, confrontamos a vida de Mead com momentos de constituição da psicologia, colocando em relevo aspectos centrais dessa interlocução nem sempre identificados. Correlacionamos a história de Mead com questões sociais, políticas, econômicas e científicas, assim como suas conexões com práticas e valores culturais específicos de sua época. Buscamos compreender sua limitada difusão na ciência psicológica, dando, assim, continuidade ao processo de (revolta do autor.This article intends to contribute to historical understanding of author/character of Psychology. We analyzed and enlarged knowledge about George Herbert Mead and the developing of his psychosocial theory. For this reason, we will explain in the text as analytical side used in our dissertation, in other words: through of the social approach in history of psychology we confront the life of Mead with facts of constitution of the psychology, emphasizing central aspects of this discussion not always identified. We correlate the history of Mead with social, politic, economic and scientific questions as well as his connections with practices and specific cultural values of his time. We look to understand his limited diffusion in the psychological science, giving, so, continuity to the process of returns of the author.

A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module

DEFF Research Database (Denmark)

Weyer, Kathrin; Boldt, Henning B; Poulsen, Christine B

2007-01-01

-A cleaves IGFBP-4 and IGFBP-5, whereas PAPP-A2 cleaves only IGFBP-5. The pappalysins contain three Lin12-Notch repeat (LNR1-3) modules, previously considered unique to the Notch receptor family in which they function to regulate receptor cleavage. In contrast to the Notch receptor where three LNR modules...

George Kubler Shifting South: Architecture History Following Geopolitics

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Sousa Santos, Eliana

2016-07-01

Full Text Available This essay aims to present the shifting relations between North America and the South - South America and the South of Europe - through the work of the historian George Kubler. At the beginning of his career as a scholar, Kubler was invited by the Department of State to participate in a conference on inter-American relations. Later, with the positioning of the United States in World War II, the transatlantic relationship between the US and Europe became more prominent. Kubler’s research interests followed this change: His research shift from South America to peripheral Southern Europe reflects an availability of funding given his country's geopolitical interests. So far, artists and other scholars have praised Kubler’s vast work regarding the art and architecture of different 'Souths' mainly as a sign of 'nonalignment' and of his attention to the condition of peripheral countries.

Caractérisation microstructurale et mécanique d’un composite cimentaire renforcé par des fibres de lin Characterizations mechanical and microstructural of flax fibre cement composite reinforced

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Boutouil M.

2012-09-01

Full Text Available Dans la perspective de valorisation des fibres de lin dans les matériaux de construction, la présente étude s’intéresse à la caractérisation microstructurale et mécanique d’un composite cimentaire renforcé par des fibres de lin. Les analyses microstructurales au MEB ont été menées pour évaluer l’homogénéité de la distribution des fibres, la qualité de l’interaction fibre/matrice et l’influence de leur présence sur les défauts microstructuraux. Le comportement mécanique en flexion du mortier renforcé par les fibres de lin est étudié en fonction de la longueur et la teneur en fibres. Les résultats indiquent une bonne adhésion entre les fibres et la matrice à l’état frais. Mais les fibres étant hydrophiles, elles gonflent pendant la prise du ciment et le retrait lors du séchage engendre alors des déchaussements. Les résultats de caractérisation mécanique sont encourageants. Tout d’abord, la fissuration du mortier due au retrait au jeune âge est fortement réduite du fait de la présence des fibres. Ensuite, la rupture brutale de la matrice en monolithe laisse place à un comportement quasi-ductile quand la teneur ou la longueur de fibre augmente. Ce changement de comportement, analysé en termes d’indice de ténacité, illustre la capacité remarquable des fibres de lin à renforcer les matrices cimentaires du fait de leurs bonnes propriétés mécaniques. With the purpose of the flax fibre valuing in construction materials, this study focuses on the characterizations mechanical and microstructural of flax fibre cement composite reinforced. The mechanical strength was studied as the function of fibre volume ratio and length. Meanwhile, the microstructural analysis investigated the homogeneity of fibre scattering, the interaction fibre/cement matrix and the influence of flax fibres on the defects microstructures. The results show the interesting mechanical properties of flax fibre in comparison with

In vitro and in vivo antimicrobial activities of seeds of Caesalpinia bonduc (Lin.) Roxb.

Science.gov (United States)

Arif, Tasleem; Mandal, T K; Kumar, Naresh; Bhosale, J D; Hole, Archana; Sharma, G L; Padhi, M M; Lavekar, G S; Dabur, Rajesh

2009-05-04

Caesalpinia bonduc (Lin.) Roxb. is a known drug in Ayurveda to treat various diseases specifically tumors, cysts and cystic fibrosis (CF). The aim of this study was to assess in vitro as well as in vivo antimicrobial activity of Caesalpinia bonduc seeds. The in vitro antimicrobial activities of seed coat and seed kernel extracts were investigated by microbroth dilution assay. In vivo activities of hydro-alcoholic extracts were investigated in rat models of chronic Pseudomonas aeruginosa pneumonia mimicking that in patients with cystic fibrosis. Various extracts of plant seeds exhibited in vitro antimicrobial activities in a range of 22-350 microg/ml. The extracts also showed activity against methicillin resistant (MR) Staphylococcus aureus and ampicillin resistant (AR) Pseudomonas aeruginosa as in the sensitive strains. In rat model of chronic Pseudomonas aeruginosa pneumonia, hydro-alcoholic extracts of Caesalpinia bonduc seed kernel (CBSK) and Caesalpinia bonduc seed coat (CBSC) were injected subcutaneously in the test groups of animals. The control groups were treated with cortisone and saline. Two weeks after challenge with Pseudomonas aeruginosa, the CBSK treated animals showed a significant bacterial clearance from the lungs (PCaesalpinia bonduc may have the potential to be promising natural medicine, with other forms of treatments, for CF patients with chronic Pseudomonas aeruginosa lung infections.

"O Romancista e o Engenho: José Lins do Rego e o regionalismo nordestino dos anos 1920 e 1930", de Mariana Ghaguri "O Romancista e o Engenho: José Lins do Rego e o regionalismo nordestino dos anos 1920 e 1930", by Mariana Chaguri

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Mário Augusto Medeiros da Silva

2013-04-01

Full Text Available Trata-se das relações entre a formalização estética do Ciclo da Cana de Açúcar e o processo social do Regionalismo Nordestino. Analisa a trajetória social e produção literária de José Lins do Rego, buscando deslindar as formas de realização social do autor, nos circuitos intelectuais e políticos de que participou (Pernambuco e Rio de Janeiro, notadamente e as condições sociais de produção de sua obra (editoras em que a mesma é publicada, recepção entre a crítica de época etc.. Em vista das disputas travadas com os Modernistas paulistas de 1922, sua interpenetração com a crise política dos anos 1930 e com as formulações de Gilberto Freyre acerca das ideias de Região e Nação, Chaguri sugere a análise do Regionalismo Nordestino como parte de um projeto estético e político, cujas intenções e consequências merecem ser sociologicamente examinadas.The book deals with the relations between the aesthetics formalization of the Sugarcane Cycle and the social process of the Brazilian Northeastern regionalism. It analyzes the social trajectory and literary work of José Lins do Rego, seeking to disclose this author's ways of social fulfillment in the intellectual and political circles he participated (especially in Pernambuco and Rio de Janeiro as well as the social conditions of production of his work (his publishers, critiques etc.. Considering his disputes with members of the 1922 modernist movement, intertwined with the political crisis of the 1930s and the formulations of Gilberto Freyre's notions about Region and Nation, Chaguri suggests the analysis of Northeastern Regionalism while part of an aesthetic and political project whose intentions and consequences deserve to be sociologically examined.

75 FR 75662 - Prince of Wales Resource Advisory Committee

Science.gov (United States)

2010-12-06

... DEPARTMENT OF AGRICULTURE Forest Service Prince of Wales Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince of Wales Resource Advisory Committee... Ferry Terminal 110 Stikine Way, Coffman Cove, Alaska. Send written comments to Prince of Wales Resource...

Sleep Disturbances in U.S. Soldiers after Deployment to Afghanistan or Iraq

Science.gov (United States)

2010-11-11

overall sleep quality and disturbances and to assess effectiveness of pharmacologic or behavioral interventions (Edinger, Wohlgemuth, Radtke ...Internet Surveys: The Tailored Design Method (2d ed.). Hobokan: John Wiley & Sons. Edinger, J. D., Wohlgemuth, W. K., Radtke , R. A., Coffman, C. J

Hans Georg Trüper (1936–2016 and His Contributions to Halophile Research

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Aharon Oren

2016-05-01

Full Text Available Prof. Hans Georg Trüper, one of the most important scientists in the field of halophile research, passed away on 9 March 2016 at the age of 79. I here present a brief obituary with special emphasis on Prof. Trüper’s contributions to our understanding of the halophilic prokaryotes and their adaptations to life in hypersaline environments. He has pioneered the study of the halophilic anoxygenic phototrophic sulfur bacteria of the Ectothiorhodospira—Halorhodospira group. Some of the species he and his group isolated from hypersaline and haloalkaline environments have become model organisms for the study of the mechanisms of haloadaptation: the functions of three major organic compounds – glycine betaine, ectoine, and trehalose – known to serve as “compatible solutes” in halophilic members of the Bacteria domain, were discovered during studies of these anoxygenic phototrophs. Prof. Trüper’s studies of hypersaline alkaline environments in Egypt also led to the isolation of the first known extremely halophilic archaeon (Natronomonas pharaonis. The guest editors dedicate this special volume of Life to the memory of Prof. Hans Georg Trüper.

St George Acute Care Team: the local variant of crisis resolution model of care.

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Cupina, Denise D; Wand, Anne P F; Phelan, Emma; Atkin, Rona

2016-10-01

The objective of this study was to describe functioning and clinical activities of the St George Acute Care Team and how it compares to the typical crisis resolution model of care. Descriptive data including demographics, sources of referral, type of clinical intervention, length of stay, diagnoses and outcomes were collected from records of all patients who were discharged from the team during a 10 week period. There were 677 referrals. The team's functions consisted of post-discharge follow-up (31%), triage and intake (30%), case management support (23%) and acute community based assessment and treatment (16%). The average length of stay was 5 days. The majority of patients were diagnosed with a mood (23%) or a psychotic (25%) disorder. Points of contrast to other reported crisis resolution teams include shorter length of stay, relatively less focus on direct clinical assessment and more telephone follow-up and triage. St George Acute Care Team provides a variety of clinical activities. The focus has shifted away from the original model of crisis resolution care to meet local and governmental requirements. © The Royal Australian and New Zealand College of Psychiatrists 2016.

Divine regie e umane variazioni. Bibbia e teatro in George Tabori

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Marco Castellari

2011-06-01

Full Text Available The present contribution outlines George Tabori’s career as a playwright and a director in the time  span between 1947 and 2007 in American and European theatre, emphasizing his position as a ‘wise stranger’  in German post-war culture. Then, the intertextual and metaphorical presence of the Holy Scriptures in his  plays The Cannibals (1969, Mein Kampf (1987, and especially The Goldberg Variations (1991 is examined  with respect to the key issues of his production: anti-Semitism before, during and after the Holocaust and  its representation on the contemporary stage.

Shaping Influences on the Leadership of Genghis Khan, George Washington, and Nelson Mandela: Applications for Educators

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Bongila, Jean-Pierre

2011-01-01

Using a prosopographical methodology this study examines common leadership influences that might have existed among Genghis Khan, George Washington, and Nelson Mandela. Shoup (2005) suggests that the following seven influences have contributed to nurturing the leadership of 12 renowned individuals: involved parents, happy childhood, formal,…

Eocene age of the Baranowski Glacier Group at Red Hill, King George Island, West Antarctica

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Mozer Anna

2015-12-01

Full Text Available Radiometric and geochemical studies were carried out at Red Hill in the southern part of King George Island (South Shetland Islands, northern Antarctic Peninsula on the Bransfield Strait coast. The rock succession at Red Hill has been determined to represent the Baranowski Glacier Group that was previously assigned a Late Cretaceous age. Two formations were distinguished within this succession: the lower Llano Point Formation and the upper Zamek Formation. These formations have stratotypes defined further to the north on the western coast of Admiralty Bay. On Red Hill the Llano Point Formation consists of terrestrial lavas and pyroclastic breccia; the Zamek Formation consist predominantly of fine to coarse tuff, pyroclastic breccia, lavas, tuffaceous mud-, silt-, and sandstone, locally conglomeratic. The lower part of the Zamek Formation contains plant detritus (Nothofagus, dicotyledonous, thermophilous ferns and numerous coal seams (vitrinitic composition that confirm the abundance of vegetation on stratovolcanic slopes and surrounding lowlands at that time. Selected basic to intermediate igneous rocks from the succession have been analysed for the whole-rock K-Ar age determination. The obtained results indicate that the Red Hill succession was formed in two stages: (1 from about 51–50 Ma; and (2 46–42 Ma, i.e. during the Early to Middle Eocene. This, in combination with other data obtained from other Baranowski Glacier Group exposures on western coast of Admiralty Bay, confirms the recently defined position of the volcano-clastic succession in the stratigraphic scheme of King George Island. The new stratigraphic position and lithofacies development of the Red Hill succession strongly suggest its correlation with other Eocene formations containing fossil plants and coal seams that commonly occur on King George Island.

Biographic Parallels as a Basis for Typological Studying of George Orwell and Ivan Bahrianyi Works

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Svitlana Korshunova

2014-11-01

Full Text Available This article deals with the problem of biographic parallelism as a basis for typological research. The main task is to find out similarities and differences in the works by George Orwell and Ivan Bahrianyi, all of them being based of the real facts from the writers' lives. The peculiarities of the literary interpretation of the biography of the both authors become the comparative basis for revealing of the common processes in their works. The research sheds the light on the interdependence between authors' motivations and its literary results. It also highlights the problem of genres chosen by the writers and of the dependence of this choice on the biographic facts usage. The article compares the genres of the authors' works from the point of view of their artistic motivation. The subject under study includes such books of the authors as “Burmese Days”, “Keep the Aspidistra Flying” and other by George Orwell, as well as “The Getsyman Garden”, “The Hunters and the Hunted” and others by Ivan Bahrianyi. It deals with the problem of the influence of the writers' biographic facts on their creation of the literary images and characters, as well as on the plots of the stories. The similarities between authors and their characters are revealed and this allows us to say that writers used their own lives as a source of inspiration and artistic motivation for the sake of making their stories credible. The article also raises the question of the nature of the writers' characters with authors' being their possible prototypes. In general, the article studies the parallels of George Orwell and Ivan Bahrianyi lives, trying to prove their compatibility in the typological field while both use their biographies as a creative method.

George Herbert Mead's Lecture on Philosophy of Education at the University of Chicago (1910-1911).

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Biesta, Gert J. J.

This paper recounts the influence of two of the great educational philosophers of this century, John Dewey and George Herbert Mead. Both men came to the University of Chicago from teaching at the University of Michigan. The men were life-long personal friends and professional colleagues. Although Mead published little during his life, his…

The Promise and Perils of the Island City of George Town (Penang as a Creative City

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Suet Leng Khoo

2015-12-01

Full Text Available The peripheral and semi-peripheral roles of islands are being challenged and contested as contemporary island cities assume positions as engines of growth and become centres of progress for driving economic development. Notably, island cities around the globe have become instrumental in shaping and influencing the dynamics of urban development as cities now compete with each other to strategically position themselves in today’s competitive global economy that leverages creativity and innovation. Particularly in a creative economy, the availability, quantity, and quality of unique cultures; creative talents; and creative/cultural industries within a city are differentiating and determining factors that can boost a city’s position and subsequently spur economic growth and progress. Against this backdrop, this paper explores the position of the island city of George Town (Penang en route to becoming a Creative City. This paper highlights the island’s urban dynamics as well as discusses the promise and perils of transforming George Town into a Creative City in its own right.

George Herbert Mead, La Philosophie du temps en perspective(s)

OpenAIRE

Leclerc, Natalia

2013-01-01

L’ouvrage intitulé La Philosophie du temps en perspective(s) comporte plusieurs textes de G. H. Mead, précédés d’une importante introduction de Michèle Leclerc-Olive, qui présente « Les figures du temps dans la philosophie de George Herbert Mead ». Son caractère pédagogique est très appréciable : elle permet en effet d’entrer progressivement dans la pensée, ou plutôt dans les différentes facettes et étapes de la réflexion de Mead. Il est extrêmement dense, et le présent compte rendu n’a pas d...

[George Herbert Mead. Thought as the conversation of interior gestures].

Science.gov (United States)

Quéré, Louis

2010-01-01

For George Herbert Mead, thinking amounts to holding an "inner conversation of gestures ". Such a conception does not seem especially original at first glance. What makes it truly original is the "social-behavioral" approach of which it is a part, and, particularly, two ideas. The first is that the conversation in question is a conversation of gestures or attitudes, and the second, that thought and reflexive intelligence arise from the internalization of an external process supported by the social mechanism of communication: that of conduct organization. It imports then to understand what distinguishes such ideas from those of the founder of behavioral psychology, John B. Watson, for whom thinking amounts to nothing other than subvocal speech.

Rethinking the Institutional Theory of George Dickie: The Art Circles

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Marko Đorđević

2016-04-01

Full Text Available This paper initially revisits the institutional theory of George Dickie, which originated in relation to Arthur Danto’s “The Artworld” and the works of other analytic philosophers dealing with art theory at the time. This contextualization is followed by an attempt at finding possible relations and theoretical developments of Dickie’s work in theorists such as Howard S. Becker and Pierre Bourdieu. The aim is to find basic correlations and differences between Dickie’s theory, Becker’s symbolic interactionism and Bourdieu’s field theory. The final segment consists of linking the interpreted theoretical terms and summing up the possibilities that arise out of them for contemporary art theory.

Fildesia Pulchra,, gen. et sp. nov.-Leaf fossil from lower Tertiary from Fildes peninsula, King George Island, Antartic

International Nuclear Information System (INIS)

Rohn, R.; Roesler, O.; Czajkowski, S.

1988-01-01

The present paper describes Fildesia pulchra gen. et sp. nov., a compound leaf collected at Fossils Hill, Fildes Peninsula (King George Island, South Shetlands, Antarctica) in vulcanoclastics of probably early Tertiary age. (author) [pt

Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes

DEFF Research Database (Denmark)

Delio, Maria; Guo, Tingwei; McDonald-McGinn, Donna M

2013-01-01

Velocardiofacial and DiGeorge syndromes, also known as 22q11.2 deletion syndrome (22q11DS), are congenital-anomaly disorders caused by a de novo hemizygous 22q11.2 deletion mediated by meiotic nonallelic homologous recombination events between low-copy repeats, also known as segmental duplication...

Birth of a Field: George Baron, Educational Administration and the Social Sciences in England, 1946-1978

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McCulloch, Gary

2014-01-01

"Educational administration and the social sciences", the landmark text coedited by Baron and Taylor in 1969, represented the study of educational administration as an applied interdisciplinary field. George Baron's own academic career reveals the struggles involved in the construction of this new field and the resistance and opposition…

Narsisisme dan Kompleks Oedipus yang Tergambar dalam Pygmalion, Karya George Bernard Shaw

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Essy Syam

2017-06-01

Full Text Available Abstract This writing analyzes narcisism and oedipuis complex as refelcted in a literary work entitles “pygmalion” written by George Bernard Shaw. Thus, the objective of this analysis is to show and to analyze how narcisism and Oedipus complex are suffered from the protagonist of this work. To reach that objective, this analysis applies psychoanalitical analysis  to demonstrate the mental condition of the main character. Related to that idea, this analysis applies adescriptive analysis method in which the result of the analysis will be described clearly. From teh presented description, it will show how the main character of this work lives his life and in his interaction with other characters will describe his mental condition.   Keywords: Pygmalion, psychoanalisis, Narcisism, Oedipus Complex.    Abstrak Tulisan ini menganalisis kasus Narsisme dan Kompleks Oedipus yang tergambar pada sebuah karya sastra berjudul Pygmalion yang ditulis oleh George  Bernard Shaw.  Maka tujuan penelitian ini adalah untuk memperlihatkan dan menganalisis bagaimana kasus narsisme dan kompleks oedipus yang dialami oleh tokoh utama karya ini. Untuk mencapai tujuan itu, kajian ini menerapkan kajian psikoanalisis  untuk memperlihatkan kondisi kejiwaan tokoh utama yang mengalami gangguan jiwa yang dimanakan Narsisime dan Kompleks Oedipus.  Kajian ini menerapkan metode deskriptif analisis dimana hasil analisis akan dideskripsikan dengan jelas. Dari deskripsi yang dijabarkan akan memperlihatkan bagaimana tokoh utama karya ini dalam kehidupannya dan interaksinya dengan tokoh yang lain memperlihatkan kondisi jiwanya.   Kata Kunci: Pygmalion, Psikoanalisis. Narsisime, Kompleks Oedipus

The story of George Huntington and his disease

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Kalyan B Bhattacharyya

2016-01-01

Full Text Available George Huntington described some families with choreiform movements in 1872 in the United States of America and since then many such families have been described in other parts of the world and works on the genetics of the disease have brought new vistas in the understanding of the disease. In 1958, Americo Negrette, a young Venezuelan physician observed similar subjects in the vicinity of Lake Maracaibo which was presented by his co-worker, Ramon Avilla Giron at New York in 1972 when United States of America had been commemorating the centenary year of Huntington′s disease. Nancy Wexler, a psychoanalyst, whose mother had been suffering from the disease attended the meeting and organized a research team to Venezuela and they systematically studied more than 18,000 individuals in order to work out a common pedigree. They identified the genetic locus of the disease in the short arm of chromosome 4 and observed that it was a trinucleotide repeat disorder.

Digital imaging of autoradiographs from paintings by Georges de La Tour (1593-1652)

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Fischer, C O; Laurenze, C; Schmidt, C; Slusallek, K

1999-01-01

The artistic work of the painter Georges de La Tour has been studied very intensively in the last few years, mainly by French and US-American art historians and natural scientists. To support the in-depth analysis of two paintings from the Kimbell Art Museum in Fort Worth, Texas, USA, two similar paintings from the Gemaeldegalerie Berlin have been investigated. The method of neutron activation autoradiography has been applied using imaging plates with digital image processing.

Les vélins du Muséum national d’histoire naturelle : une collection mise en lumière

OpenAIRE

Cardinal, Catherine

2018-01-01

Une exposition unique au Cabinet d’histoire du Jardin des plantes Très rarement, le public a pu voir la collection d’images de fleurs, de plantes, d’oiseaux et de mammifères, déposée à la bibliothèque centrale du Musée national d’histoire naturelle. La fragilité des peintures sur vélin au contact de l’air humide et de la lumière explique les précautions prises à leur égard. L’exposition d’environ cent cinquante pièces au sein du Cabinet d’histoire, d’octobre 2016 à janvier 2017, a donc consti...

Studying A Portrait of the Artist as a Young Man through Heterogeneous Philosophy of Georges Bataille

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Shataw Naseri

2014-09-01

Full Text Available Georges Bataille believes that most of his contemporary discourses were spiritual and/or intellectual ones. They were, for him, vegetation-like discourses looking upward and underlining the role of head and thinking in their paradigms. He, instead, introduced the notion of "base materialism" which highlights the role of the lower parts of the body; it is here that Bataille raises the notion of "Acéphale" who has beheaded himself with a dagger in his right hand, and thus has beheaded the ruling head of his own body as well as the heads of his surrounding social discourses. For George Bataille, humans are linguistic being entrapped forever in a language system. However, he believes that this system is full of fissures and that through transgressive moments one can experience these voids within language. Through transgression one can look directly in the abyss of language, though he/she cannot see the extremity of these voids and thus Bataille believes that one cannot reach any signified, and therefore, any Bataillean "Impossible." As one can witness, linguistic human being is entrapped within narratives of language system defining him in terms of cause and effect and their related items namely linear time and space. Georges Bataille believes that any heterogeneous element which crosses the defined taboos of the body of self and society at some transgressive moments is regarded as a "foreign body" and an "alterity." This foreign body, as he regards, at the instants of transgression experiences "sovereignty" which means that he is at the epic of being a "sovereign being," of course momentarily, because he at those moments has stepped upon any ruling borders and is bound with no taboo and thus is the "sovereign" of instants. The present study endeavors to analyze Stephen Dedalus in A Portrait of the Artist as a Young Man and his Bataillean experiences in terms of narrative and language. A Portrait will be concentrated in the light of the

Rüütel handed over the Order of the Gross of Terra Mariana to George H. W. Bush

Index Scriptorium Estoniae

2005-01-01

President Arnold Rüütel andis New Yorgis USA endisele presidendile Georg Herbert Walker Bushile Eesti iseseisvuspüüdluste toetamise eest Maarjamaa Risti I klassi ordeni. Töövisiit New Yorki 13.-17.09.2005

Early-onset psychosis in an adolescent with DiGeorge syndrome: A case report

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Keneilwe Molebatsi

2018-02-01

Full Text Available DiGeorge syndrome (DGS was first described in 1829 by Dr Angelo DiGeorge. DGS is a cluster of symptoms because of a defect in the development of the pharyngeal pouch. Evidence from cytogenetic studies has linked the pathogenesis of DGS with a deletion of a gene located in chromosome 22-band 22q11. In most affected individuals, the deletion is de novo; however, inheritance has been reported in 10% – 25% of patients. DGS commonly presents with a classical triad of conotruncal cardiac anomalies, hypoplastic thymus and hypocalcaemia. DGS may be of focus to a psychiatrist as it is associated with cognitive deficits, high rates of schizophrenia and anxiety disorders. Patients may also present to mental health care workers with learning disabilities, developmental delay and behavioural disorders such as attention-deficit or hyperactivity disorder. Mental health workers therefore play an invaluable role in the diagnosis and timely treatment of the disorder. In a resource-limited area such as Botswana, with scarce mental health professionals, paediatricians and neurologists, DGS may be frequently misdiagnosed with consequent inappropriate interventions that may increase morbidity. Herein, we present a case to raise awareness and demonstrate one of the varied ways the syndrome may present. The multifaceted nature of DGS presentation underscores the need for a multidisciplinary approach to treatment.

The occurrence and development of peat mounds on King George Island (Maritime Antarctic

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Jerzy Fabiszewski

2014-01-01

Full Text Available On King George Island, South Shetlands Islands, a type of peat formation has been discovered which has not previously been reported from the Antarctic. These formations are in shape of mounds up to 7x 15 m in area, with a peat layer of about I m thick. About twenty five cm below the surface there is a layer of permanently frozen peat. The mounds are covered by living mosses (Polytrichum alpinum and Drepanocladus uncinatus, Antarctic hair grass (Deschampsia antarctica and lichens. Erosion fissures occurring on the surface are evidence of contemporary drying and cessation of the mound's growth. The initial phase of the development of the mounds began with a community dominated by Calliergidium austro-stramineum and Deschampsia antarctica, and their further development has been due to peat accumulation formed almost entirely by Calliergidium. The location of the mounds is near a penguin rookery, which clearly conditioned the minerotrophic character of these formations, as compared with the "moss peat banks" formed by Chorisodontium aciphyllum and Polytrichum al-pestre. Moreover, the peat mounds differ from the latter in several ways, e.g. rate of growth and floristic composition. Radiocarbon dating of peat from the base of one mound gave an age of 4090±60 years B.P. This suggests that the age of the tundra on King George Island is about 5000-4000 years.

Education, Democracy, and Social Discourse: A Contemporary Response to George S. Counts and Boyd H. Bode

Science.gov (United States)

Collins, William J.

2013-01-01

Education, once known as the "great equalizer," is now being called to task for its tendency to disenfranchise and to legitimate inequality due to its obedience to the tenets of capitalism. Two of the nation's greatest educational thinkers, George S. Counts and Boyd H. Bode provided "instructions" for parents and teachers…

Remarks by president Bush and president Ilves, June 24, 2007 / George W. Bush, Toomas Hendrik Ilves

Index Scriptorium Estoniae

Bush, George W., 1946-

2007-01-01

Ameerika Ühendriikide president George W. Bush ja Eesti president Toomas Hendrik Ilves annavad lühiülevaateValge Maja ovaalkabinetis peetud kõnelusest, mille põhiteemadeks olid olukord Afganistanis ja Iraagis, viisavabadus ning küberrünnakud. Vabariigi President töövisiidil Ameerika Ühendriikides 25.-26.06.2007

Os fracassos necessários: Georges Perec e as taxonomias impossíveis de «A vida modo de usar»

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Gustavo Silveira Ribeiro

2011-10-01

Full Text Available Resumo: Este artigo estuda as relações entre a estrutura narrativa do romance  A vida modo de usar ­– romances, de Georges Perec, e a crítica dos sistemas de classificação das coisas que é feita no livro. Através da análise de episódios e personagens da obra, bem como da leitura de todos os seus paratextos, objetivamos demonstrar como a utilização criativa que Perec faz de modelos taxonômicos como listas, catálogos, verbetes e índices se realiza de modo irônico. As exaustivas enumerações presentes em A vida modo de usar explicitam a insuficiência de qualquer sistema de classificação humano, uma vez que, ao invés de ordenar o romance, as listas apenas acentuam seu caráter caótico e inextricável.Palavras-chave: Georges Perec; A vida modo de usar; taxonomia; sistema de classificação.Resumen: Este artículo estudia las relaciones entre la estructura narrativa de la novela La vie mode d’emploi ­– romances, de Georges Perec, y la crítica de los sistemas de classificación de las coisas que aparece en el libro. A través del análisis de episódios y personajes de la obra y de la lectura de todos sus paratextos, tenemos el objetivo demostrar como la utilización creativa que Perec hace de modelos taxonómicos como listas, catálogos, verbotes e índices se realiza de modo irónico. Las innumerables enumeraciones presentes en La vie mode d’emploi muestran la insuficiencia de cualquier sistema de classificación humano, una vez que, en vez de ordenar la novela, las listas solamente acentúan su carácter caótico y confuso.Palabras-clave: Georges Perec; La vie mode d’emploi; taxonomía; sistema de classificación.Keywords: Georges Perec; La vie mode d’emploi; taxonomy; classification system.

George Gamow: Scientific Amateur and Polymath

Science.gov (United States)

Harper, Eamon

George Gamow (1904-1968) was among the first of the many brilliant scientists who forsook Europe for the United States in the early 1930s. Although most were fleeing the fascist imperium of Hitler and Mussolini, Gamow was one of a few who managed to escape the burgeoning despotism of Stalin in the Soviet Union. His early application of quantum mechanics to the atomic nucleus and his subsequent insight into the role played by the physics of the atom and its nucleus in stars, galaxies, and the universe identifies him as a scientist of unusual genius. Gamow displayed a boisterous, infectious - almost Rutherfordian - interest in all aspects of pure science. His interests were broad and his industry prodigious. His scientific output covered areas as diverse as nuclear physics, astrophysics, cosmology, biological genetics, and the fascinating question of the relationship of the large-scale structure and development of the universe to the properties of elementary particles and fields. He also was an immensely imaginative and prolific author of popular expositions on scientific subjects. One who is as well-known for his authorship of the Mr. Tompkins series of science popularizations as for his contributions to the development of the physical consequences of the big-bang theory of the expanding universe and the prediction of the cosmic background radiation must be unique in the scientific pantheon.

Ice-dammed lateral lake and epishelf lake insights into Holocene dynamics of Marguerite Trough Ice Stream and George VI Ice Shelf, Alexander Island, Antarctic Peninsula

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Davies, Bethan J.; Hambrey, Michael J.; Glasser, Neil F.; Holt, Tom; Rodés, Angél; Smellie, John L.; Carrivick, Jonathan L.; Blockley, Simon P. E.

2017-12-01

We present new data regarding the past dynamics of Marguerite Trough Ice Stream, George VI Ice Shelf and valley glaciers from Ablation Point Massif on Alexander Island, Antarctic Peninsula. This ice-free oasis preserves a geological record of ice stream lateral moraines, ice-dammed lakes, ice-shelf moraines and valley glacier moraines, which we dated using cosmogenic nuclide ages. We provide one of the first detailed sediment-landform assemblage descriptions of epishelf lake shorelines. Marguerite Trough Ice Stream imprinted lateral moraines against eastern Alexander Island at 120 m at Ablation Point Massif. During deglaciation, lateral lakes formed in the Ablation and Moutonnée valleys, dammed against the ice stream in George VI Sound. Exposure ages from boulders on these shorelines yielded ages of 13.9 to 9.7 ka. Following recession of the ice stream, George VI Ice Shelf formed in George VI Sound. An epishelf lake formed at 15-20 m asl in Ablation and Moutonnée valleys, dated from 9.4 to 4.6 ka, suggesting that the lake was stable and persistent for some 5000 years. Lake-level lowering occurred after this, with the lake level at 12 m at 3.1 ± 0.4 ka and at 5 m asl today. A readvance of the valley glaciers on Alexander Island at 4.4 ± 0.7 ka is recorded by valley glacier moraines overlying epishelf lake sediments. We speculate that the glacier readvance, which occurred during a period of warmth, may have been caused by a dynamic response of the glaciers to a lowering in surface elevation of George VI Ice Shelf.

PREACHER AS A CHARACTER IN THE CREATIVE WORK OF LEO TOLSTOY AND GEORGE ELIOT

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Irina Fedorovna Gnyusova

2014-11-01

Full Text Available The article analyzes characters of clergymen and the process of creating a specifi c type of a preacher in Leo Tolstoy’s works. The researcher tries to prove that this process was strongly infl uenced by Tolstoy’s close attention to the preacher characters in George Eliot’s works. This can be proved by Tolstoy’s letters, diary and notes in the books from the writer’s personal library. The main features of Tolstoy’s preacher character are demonstrated by the example of Prince Nekhlyudov (Resurrection. Proclaiming evangelical truth, he is not a member of any confession; he does not promulgate his views, but he proves his case by his actions and his way of life. He rejects earthly comfort and goods and voluntarily becomes integrated into people’s life. Having walked his way of repentance of former sins, he cultivates the ability to forgive and have mercy. George Eliot also accents these features in the key characters of her books, analyzed in this article (Janet’s repentance, Adam Bede and Felix Holt, the Radical. Eliot’s version of preaching becomes a certain guide for Tolstoy in the process of shaping a new type of character in his late works.

Large submarine sand waves and gravel lag substrates on Georges Bank off Atlantic Canada

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Todd, B.J.; Valentine, Page C.; Harris, Peter T; Baker, E.K.

2012-01-01

Georges Bank is a large, shallow, continental shelf feature offshore of New England and Atlantic Canada. The bank is mantled with a veneer of glacial debris transported during the late Pleistocene from continental areas lying to the north. These sediments were reworked by marine processes during postglacial sea-level transgression and continue to be modified by the modern oceanic regime. The surficial geology of the Canadian portion of the bank is a widespread gravel lag overlain in places by well sorted sand occurring as bedforms. The most widespread bedforms are large, mobile, asymmetrical sand waves up to 19 m in height formed through sediment transport by strong tidal-driven and possibly storm-driven currents. Well-defined curvilinear bedform crests up to 15 km long form a complex bifurcating pattern having an overall southwest–northeast strike, which is normal to the direction of the major axis of the semidiurnal tidal current ellipse. Minor fields of immobile, symmetrical sand waves are situated in bathymetric lows. Rare mobile, asymmetrical barchan dunes are lying on the gravel lag in areas of low sand supply. On Georges Bank, the management of resources and habitats requires an understanding of the distribution of substrate types, their surface dynamics and susceptibility to movement, and their associated fauna.

É tempo de pipa: a representação da infância em Cidade de Deus, de Paulo Lins, e Lembrancinha do Adeus, de Júlio Ludemir

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Anderson Luís Nunes da Mata

2009-01-01

Full Text Available Traditionally understood as an age of innocence and learning, childhood has been shown indifferent colors in the so called "slum" narratives. Thus, poor children, who live in the urban peripheral areas, are represented in fiction as a counterface for such traditional notion of childhood. Lembrancinha do Adeus, by Julio Ludemir, and Cidade de Deus, by Paulo Lins, are both novels built upon characters who maintain only remains of childhood, which indicates both a new sociability for such children and deeper social changes.

Event for the launch of the Georges Charpak postage stamp | 26-27 February | Prévessin site

CERN Multimedia

2016-01-01

At the end of February, the French post office is releasing a new €0.70 stamp featuring an image of Georges Charpak. CERN is taking part in this event by hosting a temporary post office on the Prévessin site, which will sell the stamp with a special “first day” postmark before it goes on general sale.     Georges Charpak arrived at CERN in 1959 and, in the late 1960s, revolutionised particle detection technology by developing the multiwire proportional chamber. This technique brought particle detectors into the electronic era, setting physicists free from the laborious task of studying photographs one by one. In 1992, he was awarded the Nobel Prize in Physics for his invention. Charpak chambers are still used today in the LHC detectors and have paved the way for the technology in numerous other modern detectors. In the 1990s, Charpak was involved in developing medical applications based on particle detection technology. He was als...

George Herbert Mead on Humans and Other Animals: Social Relations After Human-Animal Studies

OpenAIRE

Rhoda Wilkie; Andrew McKinnon

2013-01-01

The turn towards nonhuman animals within sociology has shed a critical light on George Herbert Mead, his apparent prioritisation of language and the anthropocentric focus of Symbolic Interactionism (SI). Although Herbert Blumer canonised Mead as the founder of this perspective he also played a key role in excising the evolutionary and 'more-than-human' components in Mead's work. This intervention not only misrepresented Mead's intellectual project, it also made symbols the predominant concern...

A few cubic centimetres inside your skull: a interpretação dos sonhos de Winston Smith em Nineteen eighty-four, de George Orwell

OpenAIRE

Stefaisk, Stéfanie Alves

2015-01-01

Aliando Nineteen Eighty-Four, de George Orwell, e A Interpretação dos Sonhos, de Sigmund Freud, esta dissertação pretende interpretar os sonhos da personagem principal da obra de George Orwell para, assim, compreender os mecanismos de repressão da personagem, suas neuroses, traumas, fobias, anseios e desejos, e tentar perceber a fundo quem ele, no seu mais profundo inconsciente, realmente é. Analisando sete sonhos relatados pela personagem durante a narrativa, pretendo aplicar a metodologi...

George E. Pake Prize Talk: A Peaceful and Free World Through Technology

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Robinson, C. Paul

2003-03-01

The award of the George E. Pake Prize honors not just me, but the many men and women who have devoted themselves to ``helping our nation secure a peaceful and free world through technology." These words comprise the core purpose of Sandia National Laboratories, and are also an apt description of Los Alamos, where I spent my early career, and of the US delegation to the Nuclear Testing Talks, where I served as the Ambassador and Chief Negotiator. In this talk, I will reflect on the opportunities to benefit the nation's and mankind's future through service in such endeavors.

An accidental statistician the life and memories of George E. P. Box

CERN Document Server

Box, George E P

2013-01-01

Celebrating the life of an admired pioneer in statisticsIn this captivating and inspiring memoir, world-renowned statistician George E. P. Box offers a firsthand account of his life and statistical work. Writing in an engaging, charming style, Dr. Box reveals the unlikely events that led him to a career in statistics, beginning with his job as a chemist conducting experiments for the British army during World War II. At this turning point in his life and career, Dr. Box taught himself the statistical methods necessary to analyze his own findings when there were no statist

Depositional environment of near-surface sediments, King George Basin, Bransfield Strait, Antarctica

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Yoon, H. I.; Park, B. K.; Chang, S. K.; Han, M. W.; Oh, J. K.

1994-03-01

Four sediment cores were collected to determine the depositional environments of the King George Basin northeast of Bransfield Strait, Antarctica. The cored section revealed three distinct lithofacies: laminated siliceous ooze derived from an increased paleoproductivity near the receding sea-ice edges, massive muds that resulted from hemipelagic sedimentation in open water, and graded sediments that originated from nearby local seamounts by turbidity currents. Clay mineral data of the cores indicate a decreasing importance of volcanic activity through time. Active volcanism and hydrothermal activity appear to be responsible for the enrichment of smectite near the Penguin and Bridgeman Islands.

Suburban School Opens Elementary Campus in the Heart of Memphis: St. George's Independent School, Memphis, Tennessee

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Stewart, Sarah

2016-01-01

St. George's has nearly 1,150 students on three campuses: an elementary campus in Germantown and a middle/upper school campus in Collierville, both suburbs of Memphis, and a second elementary campus in Memphis. The Memphis campus serves 140 students in pre-K-5th grade. All Memphis campus students receive financial aid based on need, and…

Assessing the Debt: George W. Bush's Legacy and the Future of Public Education under Barack Obama

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Means, Alex; Taylor, Kendall

2010-01-01

This article utilizes Gloria Ladson-Billings' notion of educational debt in order to explore the historical, economic, and cultural politics of education reform under George W. Bush and Barack Obama. It tracks the No Child Left Behind Act across a number of fields in order to claim that Bush's expansion of the educational debt should be understood…

Evaluation of antimicrobial resistance among Salmonella and Shigella isolates in the University Hospital "St. George," Plovdiv, Bulgaria.

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Petrov, Michael M; Petrova, Atanaska; Stanimirova, Irina; Mircheva-Topalova, Marina; Koycheva, Lalka; Velcheva, Rayna; Stoycheva-Vartigova, Mariana; Raycheva, Ralitsa; Asseva, Galina; Petrov, Petar; Kardjeva, Velichka; Murdjeva, Marianna

2017-03-01

The aim of this work is to study the epidemiology and antimicrobial resistance to the most commonly used antibiotics for the treatment of acute gastroenteritis caused by Salmonella and Shigella at the largest Bulgarian hospital-University Hospital "St. George," Plovdiv-for the period 2009-2013. Two hundred ninety strains were in vitro tested for resistance to 15 antimicrobial agents. The presence of extended-spectrum beta-lactamases (ESBLs) was demonstrated by a variety of specialized tests. For comparison, a collection of 28 strains submitted by the National Reference Laboratory (NRL) "Enteric Infections" at the National Center of Infectious and Parasitic Diseases (NCIPD), Sofia, was also tested for the production of ESBLs. In isolates, phenotypically demonstrated as ESBL producers, polymerase chain reaction (PCR) detection of the genes bla-CTX-M, bla-SHV, and bla-TEM was performed. Among the 290 tested isolates, only two- Salmonella serotype Livingstone and Shigella flexneri-were phenotypically proven to be ESBL producers. Only 4 strains from the collection of 28, submitted from the NRL "Intestinal Infections" in NCIPD, Sofia, were phenotypically confirmed as ESBL producers. The presence of the bla-CTX-M gene was detected in all of the tested strains (4 from NRL, NCIPD, Sofia, and 2 from the University Hospital St. George, Plovdiv), the bla-SHV gene only in strain S. Livingstone from Plovdiv, and the bla-TEM gene in two from Sofia and one (again S. Livingstone) from Plovdiv. In conclusion, Salmonella and Shigella isolates from patients hospitalized at the University Hospital St. George, Plovdiv, with acute gastroenteritis demonstrate good susceptibility to the most commonly used antibiotic agents, including azithromycin.

Immunotherapy trials for type 1 diabetes: the contribution of George Eisenbarth.

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Skyler, Jay S; Pugliese, Alberto

2013-06-01

Type 1 diabetes (T1D) results from the autoimmune destruction of pancreatic β-cells, and as such it should respond to immunotherapy. George Eisenbarth gave many significant contributions to this field. He has been involved at some level in most immunotherapy trials during the past three decades. He was among the pioneers who attempted immunotherapy approaches in patients with recent-onset T1D. In the early 1980s he began studying relatives of those with the disease, leading to the concept that T1D was a chronic autoimmune disease, in which islet autoimmune responses would silently destroy β-cells and cause progressive impairment of insulin secretion, years to months before a diagnosis was made. Consequently, he was one of the first to attempt immune intervention in people at high risk of T1D. Throughout his career he developed autoantibody assays and predictive models (which included metabolic testing and later genetics) to identify individuals at risk of T1D. He provided seminal intellectual contributions and critical tools for prevention trials. His focus on insulin as a critical autoantigen led to multiple prevention trials, including the Diabetes Prevention Trial-Type 1 (DPT-1), which studied both parenteral and oral insulin. In the DPT-1 Oral Insulin Trial, a cohort with higher levels of insulin autoantibodies was identified that appeared to have delayed disease progression. Type 1 Diabetes TrialNet is conducting a new trial to verify or refute this observation. Moreover, George identified and tested in the mouse small molecules that block or modulate presentation of a key insulin peptide and in turn prevent the activation of insulin-specific T-lymphocytes. Thus, we believe his greatest contribution is yet to come, as in the near future we should see this most recent work translate into clinical trials.

Business as Usual: Amazon.com and the Academic Library

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Van Ullen, Mary K.; Germain, Carol Anne

2002-01-01

In 1999, Steve Coffman proposed that libraries form a single interlibrary loan based entity patterned after Amazon.com. This study examined the suitability of Amazon.com's Web interface and record enhancements for academic libraries. Amazon.com could not deliver circulating monographs in the University at Albany Libraries' collection quickly…

Violence and the Sacred in Georges Bataille's Philosophy

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A. ZYGMONT

2015-06-01

Full Text Available The article considers the concepts of violence and the sacred in the work of the French philosopher Georges Bataille. The author traces back the transformations of the concept of violence throughout the thinker’s carrier, namely in his early literary and philosophical experiences of the late 20s — early 30s, his reports for the College of Sociology (1937–1939 and his «systematic» postwar writings (1945–1962. The author also puts forward the hypothesis of the connection between the concept violence and the concept the sacred and demonstrates that it is most thoroughly represented in the last period of his work, although it may have been noted before. Diachronic consideration of the formation of these concepts allows the author to trace their correlation from the more or less random links mediated by artistic images and the other notions (sacrifi ce, for example to their explicit identification with each other and the systematic development in relation to such concepts as nature, life, being, intimacy, the animal state, expenditure, sacrifice, war and eroticism

George Sand et la République (entretien avec Michelle Perrot

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Jean-Claude Vimont

2012-06-01

Full Text Available TRAMES : Vous présentez les figures passées de l’engagement politique, dans un numéro spécial de Vingtième siècle (n° 60, sous le titre « La cause du peuple » , éphémère journal de George Sand en avril 1848 et organe maoïste de la Gauche Prolétarienne après mai 1968. Est-ce pour fixer un point de départ, les années 1840, à la généalogie des engagements d’écrivains, d’intellectuels auprès d’un peuple qui est en passe de devenir prolétariat industriel, classe ouvrière ? Y a-t-il une filiation ...

Saint george “μέγας δούξ” - an icon from the Byzantine Museum of Kastoria

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Sisiou Iōannēs

2014-01-01

Full Text Available In this paper, the icon of St George with the epithet Megas Doux (Μέγας Δούξ, held in the Kastoria Museum, is published for the first time; it dates from the first decade of the fourteenth century. The discussion lists all known examples of holy warriors with the same epithet preserved in the area of Kastoria. Based on these examples it is concluded that the epithet was not only related to St Demetrios. During the reign of Andronikos II Palaiologos, donors who bore the title of dux wished to endow their personal patron saint - most commonly Demetrios and George - with the same title.

Huella de Hans-Georg Gadamer en Reinhart Koselleck. Aportes a la historia conceptual

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Ramos Rodríguez, Froilán

2018-01-01

Resumen Este artículo analiza la influencia de la hermenéutica de Hans-Georg Gadamer (1900-2002) sobre la historia conceptual de Reinhart Koselleck (1923-2006), así como la relación intelectual entre ambos. En este sentido, se hace una revisión de los principales rasgos biográficos de ambos académicos, y un reexamen de las ideas -de temporalidad y lenguaje-, que inspiraron y contribuyeron en su formación y obras, para analizar las premisas primordiales de sus trabajos, en Verdad y método, Fut...

H.GEORGE FREDERİCKSON VE KAMU YÖNETİMİ DİSİPLİNİNDEKİ YERİ

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CİĞEROĞLU, MISRA; ÖZGÜR, HÜSEYİN

2015-01-01

This study intended to examine H. George Frederickson, who has an important role in American public administration literature and one of the founders of the new public administration movement, his contributions and views related to public administration discipline. In this context, new public administration movement, “public administration” notion, governance and ethics topics that Frederickson has frequently published are studied. First of all, his arguments concerning new public administrat...

To Bind Ties between the School and Tribal Life: Educational Policy for Africans under George Stark in Zimbabwe.

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Mungazi, Dickson A.

1989-01-01

Contends that educational policy in Zimbabwe from 1934 to 1954 served the political purposes of the colonial government and neglected genuine educational development of the colonized Africans. During George Stark's tenure as Director of Native Education, Zimbabweans were consigned to "practical training" programs and were denied access…

Learning from eponyms: George F. Odland and Odland bodies

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Rajiv Joshi

2014-01-01

Full Text Available Odland bodies (lamellar bodies are small sub-cellular structures of size 200-300 nm that are present in the upper spinous and granular cell layers of the epidermis. These act as processing and repository areas for lipids that contribute to the epidermal permeability barrier. They also contain proteases, cathepsin D, kallikrein and other proteins including corneo-desmosins. Recent information also credits them with a role in the local innate immune response as they contain beta 2 defensins, which are anti-microbial peptides with potent activity against Gram-negative bacteria and candida. Odland bodies are important for maintaining homeostasis of the epidermis and are involved in epidermal permeability barrier function, desquamation of keratinocytes, formation of the cornified envelope and in local anti-microbial immunity. This article reviews the structure and functions of these bodies with a brief biography of George F. Odland who first described these bodies in 1960 and whose name is eponymically associated with them.

76 FR 38419 - United States v. George's Foods, LLC, et. al.; Proposed Final Judgment and Competitive Impact...

Science.gov (United States)

2011-06-30

... provisions of Section 5(a) of the Clayton Act, 15 U.S.C. 16(a), the proposed Final Judgment has no prima facie effect in any subsequent private lawsuit that may be brought against George's. V. Procedures... in protecting the public interest is one of insuring that the government has not breached its duty to...

Growing Shrubs at the George O. White State Forest Nursery: What Has Worked and What Has Not

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Gregory Hoss

2006-01-01

At the George O. White State Forest Nursery in Licking, MO, we annually grow about 20 species of shrubs. That number has been larger in some years. For most species, we purchase seeds locally and process them at our nursery. Our shrubs are used for wetland restoration, windbreaks, visual screens, riparian buffers, and wildlife plantings.

La fouille du fort Saint-Georges à Chinon (Indre-et-Loire. Premiers résultats The excavation of fort Saint-Georges at Chinon (Indre-et-Loire. First results

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Bruno Dufaÿ

2006-05-01

Full Text Available Cette note présente les premiers résultats des fouilles menées en 2003 et 2004 sur la quasi-totalité du fort Saint-Georges à Chinon (Indre-et-Loire. Celui-ci est l’un des trois éléments de la forteresse médiévale qui domine la ville. La fouille a permis de préciser la fonction du fort, construit dans la deuxième moitié du XIIe s., à l’époque où Chinon est le centre administratif des possessions continentales des Plantagenêt, rois d’Angleterre. Du point de vue militaire, il formait une fortification avancée, protégeant le château principal, selon une structure que Richard Cœur de Lion appliquera au Château Gaillard. À l’intérieur, de vastes bâtiments constituaient des logis, conçus peut-être au départ pour héberger la chancellerie royale.This article presents the first results of the excavations undertaken in 2003 and 2004 over almost all of the Fort Saint-Georges at Chinon (Indre-et-Loire, one of three elements of the medieval fortress which dominates the town. The excavation enabled us to clarify the function of the fort, built in the 2nd half of the 12th century at a time when Chinon was the administrative centre of the continental possesions of the Plantagenet King of England. From a military point of view, it formed an advanced fortification protecting the main castle, within a structure that Richard the Lionheart would apply to the Chayeau Gaillard. Inside, some vast buildings made up the dwellings, designed perhaps initially to house the royal chanceller.

Reproductive output of mosses under experimental warming on Fildes Peninsula, King George Island, maritime Antarctica

OpenAIRE

Casanova-Katny, A.; Torres-Mellado, G. A.; Eppley, S. M.

2016-01-01

BACKGROUND: Mosses dominate much of the vegetation in the Antarctic, but the effect of climatic change on moss growth and sexual reproduction has scarcely been studied. In Antarctica, mosses infrequently produce sporophytes; whether this is due to physiological limitation or an adaptive response is unknown. We studied the effect of experimental warming (with Open Top Chambers, OTCs) on sporophyte production on Fildes Peninsula, King George Island for four moss species (Bartramia patens, Henne...

Georges Teissier (1900–1972) and the Modern Synthesis in France

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Loison, Laurent

2013-01-01

This Perspectives is devoted to the ideas of the French zoologist Georges Teissier about the mechanisms of evolution and the relations between micro- and macroevolution. Working in an almost universally neo-Lamarckian context in France, Teissier was one of the very few Darwinians there at the time of the evolutionary synthesis. The general atmosphere of French zoology during the 1920s and the 1930s will first be recalled, to understand the specific conditions in which Teissier became a zoologist. After a brief overview of his joint work with Philippe L’Héritier on the experimental genetics of Drosophila, this article describes the ways Teissier, during the 1950s, conceptualized the mechanisms that could allow for macroevolutionary transitions. PMID:24089462

El materialismo de Georges Bataille. Una lectura desde Nietzsche y Marx

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Vicente Montenegro Bralic

2015-01-01

Full Text Available La noción de materialismo de Georges Bataille se erige como una crítica a las concepciones metafísicas o idealistas del materialismo A partir de una reconstrucción de lo que Bataille expone en distintos lugares de sus escritos de juventud, se propone una interpretación del “bajo materialismo” de Bataille desde su particular lectura de Nietzsche y Marx, que, al intentar hacer compatibles elementos de una y otra filosofía, desemboca en una discusión crítica con ambos autores. Esta discusión que, a su vez, puede ser leída como antecedente de una deconstrucción del materialismo como la que lleva a cabo Jacques Derrida.

Qualidade de um sistema latossolo-argissolo como receptor de efluentes no município de Lins(SP Quality of a latosol-argisol system in the county of Lins/SP, Brazil

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Liliane Ibrahim

2008-12-01

Full Text Available Este trabalho objetivou caracterizar um sistema de solos, evidenciando a propriedades que possam esclarecer sua dinâmica e contribuir para a definição de critérios que condicionem a aptidão destes solos como receptores de efluentes. Trata-se de uma área experimental de estudos, contígua à Estação de Tratamento de Esgoto do município de Lins (SP, onde o efluente é gerado a partir do tratamento de esgoto por sistema de lagoas de estabilização. Os solos, situados ao longo de uma vertente com ligeira inclinação, foram caracterizados por meio de análises, morfológica, granulométrica, química, mineralógica e micromorfológica, realizadas em amostras coletadas em cinco trincheiras em toposseqüência. Os solos são desenvolvidos a partir dos sedimentos arenosos da Formação Adamantina (Grupo Bauru e constituem um sistema Latossolo - Argissolo onde a transição Bw - Bt ocorre lateralmente do topo para a base da vertente. Foram identificadas três fases pedogenéticas nesta associação de solos. A primeira, argiluviação e adensamento de partículas, responsável pela formação dos horizontes texturais, foi superposta pelos processos de latossolização e hidromorfismo, atuantes na dinâmica atual destes solos. Análises micromorfológicas mostraram tratar-se de solos com intensa porosidade, caracterizada pelo empilhamento dos grãos do esqueleto quartzoso amplamente predominante e pelo arranjo entre os microagregados granulares. A permeabilidade é ainda favorecida pela intensa ação da mesofauna. Os solos são distróficos e compostos por caulinita e óxidos de Fe na fração argilosa. Por constituírem um sistema frágil, a disposição de quaisquer tipos de resíduos nestes solos requer o monitoramento constante de suas propriedades, tanto para a manutenção, quanto para a recuperação da qualidade desta cobertura pedológica.The purpose of this study was the characterization of a soil system, focused on proprieties that

90 Years Later: Reflections on "The Registrar: A Profession"

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von Munkwitz-Smith, Jeffrey

2016-01-01

Jeffrey Von Munkwitz-Smith recently retired as Assistant Vice President and University Registrar at Boston University. This article provides a commentary by Von Munkwitz-Smith on an address given by Lotus Delta Coffman (then president of the University of Minnesota) in 1926 at the annual meeting of the American Association of Collegiate…

Ola Hansson ja Georg Brandes : märkusi Nietzsche esimese retseptsiooni kohta / Alessandro Fambrini ; tlk. Mart Kivimäe

Index Scriptorium Estoniae

Fambrini, Alessandro

2006-01-01

F. Nietzsche loomingu mõjudest skandinaavia kirjandusele. Taanlase Georg Brandese käsitlusest "Friedrich Nietzsche. Traktaat aristokraatlikust radikalismist" ja rootslase Ola Hanssoni esseest "Friedrich Nietzsche. Tema süsteemi ja isiksuse piirjooned", autorite omavahelistest vastuoludest ja poleemikast seoses F. Nietzsche loomingu käsitlemisega

GEORG GRODDECK: "THE PINCH OF PEPPER" OF PSYCHOANALYSIS(.).

Science.gov (United States)

Poster, Mark F; Hristeva, Galina; Giefer, Michael

2016-06-01

The life and works of Georg Groddeck are reviewed and placed in historical context as a physician and a pioneer of psychoanalysis, psychosomatic medicine, and an epistolary style of writing. His Das Es concept stimulated Freud to construct his tripartite model of the mind. Groddeck, however, used Das Es to facilitate receptivity to unconscious communication with his patients. His "maternal turn" transformed his treatment approach from an authoritarian position to a dialectical process. Groddeck was a generative influence on the development of Frieda Fromm-Reichmann, Erich Fromm, and Karen Horney. He was also the mid-wife of the late-life burst of creativity of his friend and patient Sándor Ferenczi. Together, Groddeck and Ferenczi provided the impetus for a paradigm shift in psychoanalysis that emphasized the maternal transference, child-like creativity, and a dialogue of the unconscious that foreshadowed contemporary interest in intersubjectivity and field theory. They were progenitors of the relational turn and tradition in psychoanalysis. Growing interest in interpsychic communication and field theory is bringing about a convergence of theorizing among pluralistic psychoanalytic schools that date back to 1923 when Freud appropriated Groddeck's Das Es and radically altered its meaning and use.

George William Hill, the Great but Unknown 19th Century Celestial Mechanician

Science.gov (United States)

Corbin, Brenda G.

2012-01-01

George William Hill (1838-1914) has long been considered one of the most famous and talented celestial mechanicians of the past century and a half. However, many people have never heard of him and his work. Simon Newcomb said he "will easily rank as the greatest master of mathematical astronomy during the last quarter of the nineteenth century.” After receiving a B.A. at Rutgers in 1859, Hill began work in 1861 at the office of the American Ephemeris and Nautical Almanac in Cambridge, MA. He moved to Washington with the group in 1882 which then became part of the U. S. Naval Observatory. Newcomb, beginning his work on planetary motion, assigned the theory of Jupiter and Saturn to him, calling it about the most difficult topic. Hill's work was published by the USNO in 1890 as A New Theory of Jupiter and Saturn. From 1898 to 1901, Hill lectured on the subject of celestial mechanics at Columbia University in a position created just for him. After 1892 and until his death, he lived at the family homestead in West Nyack, NY. He never married, was something of a recluse, and spent most of his time with his books and research. Hill was an amateur botanist and enjoyed exploring on long walks in the countryside. Many honors and awards came to him during his lifetime, both from the U.S. and abroad, including serving as president of the American Mathematical Society. All of Hill's mathematical and astronomical research was incorporated in The Collected Mathematical Works of George William Hill. This work, containing a preface in French by Poincare, was published in 4 large volumes by the Carnegie Institution of Washington in 1905.

La sociología en el Leteo: el largo adiós de Georges Gurvitch* La sociología en el Leteo: el largo adiós de Georges Gurvitch*

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José María Pérez-agote Aguirre

2006-01-01

Full Text Available This article intends to call the reader’s attention upon George Gurvitch’s sociology. It seeks to highlight both its intrinsic value and its significance in approaching the micro-macro problem as a core subject in the sociological debate of the last two decades of the 20th century. Gurvitch, who introduced the terms microsociology and macrosociology in the sociological field, is the autor of a model for the representation of social reality in which the micro-macro are succesfully integrated. This fact makes us vindicate his often neglected presence in the sociological debate carried out during the 1980´s, especially in the work of Jeffrey Alexander.Este artículo pretende llamar la atención sobre el interés actual de la sociología de Georges Gurvitch, tanto por su valor intrínseco como por la singular relevancia que adquiere en relación al problema de la síntesis micro-macro, uno de los temas que ha dominado la teoría sociológica en las últimas décadas. Se recuerda a Gurvitch como introductor en el lenguaje sociológico de los vocablos microsociología y macrosociología y, ante todo, como autor de un modelo de representación de la realidad social en el que lo micro y lo macro se integran dialécticamente con el propósito, logrado en alto grado, de reflejar fielmente la inagotable complejidad y riqueza de la vida social. Todo ello hace inexcusable su olvido por parte de quienes propiciaron el debate en los ochenta, especialmente Jeffrey Alexander.

Convective descent simulations of drilling discharges on Georges and Sable Island banks

International Nuclear Information System (INIS)

Andrade, Y.; Loder, J.W.

1997-01-01

Factors affecting the fate of drilling mud discharges on Georges and Sable Island Banks were examined. The Koh and Chang jet discharge model was used to simulate the convective descent of a jet discharge of relatively dense materials at sites representing different hydrographic and depth regimes with a range of mud densities, and different discharge configurations, ocean currents and seasonal stratifications. The study revealed the dependence of the depth of descent and properties of the discharge plume on the discharge configuration and oceanographic conditions. The factors that affected the depth of descent were mud density, depth of release, initial downward volume flux of the discharge, current strength and ocean stratification. 22 refs., 3 tabs., 59 figs

The Materialism of Georges Bataille. A Reading from the Perspective of Nietzsche and Marx

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Vicente Montenegro Bralic

2015-12-01

Full Text Available Georges Bataille’s notion of materialism can be seen as a critique of metaphysical or idealist conceptions of materialism. On the basis of the reconstruction of Bataille’s statements in his different early writings, the paper provides an interpretation of Bataille’s “base materialism” based on his peculiar reading of Nietzsche and Marx. The attempt to make compatible elements from both philosophies leads to a critical discussion with the authors, which, in turn, can be read as a forerunner of the deconstruction of materialism carried out by Jacques Derrida.

Geologic and operational summary, COST No. 1 well, Georges Bank area, North Atlantic OCS

Science.gov (United States)

Amato, Roger V.; Bebout, John W.

1980-01-01

The first Continental Offshore Stratigraphic Test (COST) well on the U.S. North Atlantic Outer Continental Shelf (OCS) was drilled by Ocean Production Company between April 6 and July 26, 1976, and designated the COST No. G-l. Geological and engineering data obtained from this deep well in the Georges Bank Basin were used by the 31 participating companies and the U.S. Geological Survey (USGS) for evaluating the petroleum potential and possible drilling problems in the U.S. North Atlantic OCS area in preparation for Lease Sale 42 held on December 18, 1979.

Patterns and Scales of Variability in the Optical Properties of Georges Bank Waters, with Special Reference to Phytoplankton Biomass and Production

National Research Council Canada - National Science Library

Sosik, Heidi

1999-01-01

.... This is being achieved through a field effort to make measurements of time series and spatial distributions of both apparent and inherent optical properties in the waters of Georges Bank and the Gulf of Maine...

Gene expression profile and functionality of ESC-derived Lin-ckit+Sca-1+ cells are distinct from Lin-ckit+Sca-1+ cells isolated from fetal liver or bone marrow.

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Irina Fernandez

Full Text Available In vitro bioreactor-based cultures are being extensively investigated for large-scale production of differentiated cells from embryonic stem cells (ESCs. However, it is unclear whether in vitro ESC-derived progenitors have similar gene expression profiles and functionalities as their in vivo counterparts. This is crucial in establishing the validity of ESC-derived cells as replacements for adult-isolated cells for clinical therapies. In this study, we compared the gene expression profiles of Lin-ckit+Sca-1+ (LKS cells generated in vitro from mouse ESCs using either static or bioreactor-based cultures, with that of native LKS cells isolated from mouse fetal liver (FL or bone marrow (BM. We found that in vitro-generated LKS cells were more similar to FL- than to BM LKS cells in gene expression. Further, when compared to cells derived from bioreactor cultures, static culture-derived LKS cells showed fewer differentially expressed genes relative to both in vivo LKS populations. Overall, the expression of hematopoietic genes was lower in ESC-derived LKS cells compared to cells from BM and FL, while the levels of non-hematopoietic genes were up-regulated. In order to determine if these molecular profiles correlated with functionality, we evaluated ESC-derived LKS cells for in vitro hematopoietic-differentiation and colony formation (CFU assay. Although static culture-generated cells failed to form any colonies, they did differentiate into CD11c+ and B220+ cells indicating some hematopoietic potential. In contrast, bioreactor-derived LKS cells, when differentiated under the same conditions failed to produce any B220+ or CD11c+ cells and did not form colonies, indicating that these cells are not hematopoietic progenitors. We conclude that in vitro culture conditions significantly affect the transcriptome and functionality of ESC-derived LKS cells and although in vitro differentiated LKS cells were lineage negative and expressed both ckit and Sca-1

Georges Lemaître et la théorie du big bang qu'y avait-t-il au commencement de l'univers ?

CERN Document Server

Landa, Pauline

2015-01-01

Découvrez enfin tout ce qu'il faut savoir sur Georges Lemaître et ses inventions en moins d'une heure !L'origine de l'univers, voilà une problématique qui a tenu en haleine de très nombreux scientifiques. Alors que l'on pourrait croire que l'homme s'est posé cette question depuis la nuit des temps, il n'en est rien. C'est Georges Lemaître, un prêtre belge et grand astrophysicien, qui le premier cherche à dater l'univers et à tenter de découvrir ce qu'il y avait au commencement, alors même que l'ensemble de la communauté scientifique était persuadé qu'il avait toujours exis

French Regulatory Framework for the Recycling/Reuse of Nuclear Waste and the Dismantling of George Besse Gaseous Diffusion Plant

Energy Technology Data Exchange (ETDEWEB)

Themines, R., E-mail: robert.themines@areva.com [AREVA (France)

2011-07-15

The regulatory framework in France governing the management of materials containing low levels of radionuclides is described. The plans for the management of the materials arising from the dismantling of the Georges Besse Gaseous Diffusion Plant are described as an example of the application of the regulations. (author)

Elemental composition of Usnea sp lichen from Potter Peninsula, 25 de Mayo (King George) Island, Antarctica

International Nuclear Information System (INIS)

Bubach, Débora; Catán, Soledad Perez; Di Fonzo, Carla; Dopchiz, Laura

2016-01-01

Several pollutants, which include metals, are present in the Antarctic atmosphere, snow, marine and terrestrial organisms. This work reports the elements incorporated by Usnea sp thalli in Potter Peninsula, 25 de Mayo (King George) Island, South Shetlands, Antarctica. Geological origin was analyzed as possible sources of elements. For this purpose, correlations were done using a geochemical tracer, principal component analysis and enrichment factors were computed. Lithophile elements from particulate matter were present in most of the sampling sites. Bromine, Se and Hg showed the highest enrichment factors suggesting other sources than the particulate matter. Mercury values found in Usnea sp were in the same range as those reported for Deception Island (South Shetlands) and remote areas from the Patagonia Andes. - Highlights: • Hg enrichment factor was higher in ASPA than in human settlements area. • The elemental composition in Usnea sp from Antarctica reflected the human influence. • Bromine, Ca, Sr, Se, Fe, Hg and K contents indicated origins natural and anthropic. • The data will be considered as baselines for Potter Peninsula, King George Island. - This study provides recent element contents in Usnea sp from Potter Peninsula, South Shetland Islands, Antarctica. Some of them are the first concentration reported by Argentina.

FROM MRS WARREN’S PROFESSION TO PRESS CUTTINGS: THE WOMAN QUESTION IN GEORGE BERNARD SHAW’S PLAYS

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Banu ÖĞÜNÇ

2017-06-01

Full Text Available George Bernard Shaw, who introduced social realism to the British stage, is considered to be the most significant playwright of the Victorian era. In his plays, he challenged the typical Victorian representation of female characters and introduced a new woman type who stands as a powerful and independent figure. Shaw’s female characters can be analysed in line with the suffragette movement, the fight given by British women to gain their right to vote. In this regard, Shaw’s play Mrs Warren’s Profession exemplifies a female character who can be considered as an advocate for female liberation and power. On the other hand, his play Press Cuttings, which was specifically written to support the suffragette movement, neither exemplifies the new woman image presented by Shaw in his plays nor contributes to the suffragette movement. Hence, this study aims to discuss the theme of the rights of women and to focus on George Bernard Shaw’s Mrs Warren’s Profession and Press Cuttings by means of Shaw’s involvement in and support for the suffragette movement from the Victorian to the Edwardian era.

George Santayana’s Teleological Poetics: Inspiration, Knowledge and Happiness in Reason in Art

OpenAIRE

Rocío Badía Fumaz

2012-01-01

With The Life of Reason George Santayana earned his reputation as philosopher; this is due to its length but also because it is his most detailed moral work. The fourth volume of the work, entitled Reason in Art, analyzes both the historical and synchronic origin of the work of art. Santayana’s Poetics are built on the strained relationship he draws between, ethics and aesthetics, ingenium and ars, literature and philosophy. He develops a teleological and eudaimonistic approach which centres ...

Newcastle disease virus in penguins from King George Island on the Antarctic region.

Science.gov (United States)

Thomazelli, Luciano M; Araujo, Jansen; Oliveira, Danielle B; Sanfilippo, Luiz; Ferreira, Carolina S; Brentano, Liana; Pelizari, Vivian H; Nakayama, Cristiane; Duarte, Rubens; Hurtado, Renata; Branco, Joaquim O; Walker, David; Durigon, Edison L

2010-11-20

Here we report the isolation of Newcastle disease virus (NDV) from cloacal swabs obtained from penguins in the South Atlantic Antarctic region (62°08S, 58°25W). Samples of 100 penguins from King George Island were tested by real-time PCR, of which 2 (2%) were positive for NDV. The positive samples were isolated in embryonated chicken eggs and their matrix and fusion proteins genes were partially sequenced. This was complemented by the serological study performed on the blood of the same specimens, which resulted in a 33.3% rate of positivity. Copyright © 2010 Elsevier B.V. All rights reserved.

Theme: Motivating Students.

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Gartin, Stacy A.; And Others

1993-01-01

Includes "How Do I Turn Your Crank to Get You Going?" (Gartin); "How Do You Say 'I Don't Know' and Not Feel Guilty?" (Dickson); "Basics of Motivation" (Rankin); "Challenge to Lead Motivates Students" (D'Haem, Krueger); "Don't Just Tell Me, Teach Me!" (Custer, Leugers); "The 'I' in Motivation" (Woody); and "Student Self Discipline Scale" (Coffman).…

Phrenology, heredity and progress in George Combe's Constitution of Man.

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Jenkins, Bill

2015-09-01

The Constitution of Man by George Combe (1828) was probably the most influential phrenological work of the nineteenth century. It not only offered an exposition of the phrenological theory of the mind, but also presented Combe's vision of universal human progress through the inheritance of acquired mental attributes. In the decades before the publication of Darwin's Origin of Species, the Constitution was probably the single most important vehicle for the dissemination of naturalistic progressivism in the English-speaking world. Although there is a significant literature on the social and cultural context of phrenology, the role of heredity in Combe's thought has been less thoroughly explored, although both John van Wyhe and Victor L. Hilts have linked Combe's views on heredity with the transformist theories of Jean-Baptiste Lamarck. In this paper I examine the origin, nature and significance of his ideas and argue that Combe's hereditarianism was not directly related to Lamarckian transformism but formed part of a wider discourse on heredity in the early nineteenth century.

A Formalism for the Consistent Description of Non-Linear Elasticity of Anisotropic Media Formalisme pour une description cohérente de l'élasticité non linéaire des milieux anisotropes

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Helbig K.

2006-12-01

deviation can be expressed by the relative change of the eigenstiffnesses and by the variation in the direction of the eigenstrains (expressed as vectors in six-dimensional strain space. The suggested procedure is applied to the two materials discussed by Rasolofosaon and Yin (1996. The results allow a heuristic evaluation of the meaning of the reference strain , the square root of the ratio of the norms of the fourth-rank and sixth-rank stiffness tensors. It is stressed that this is not a new theory of non-linearity, but only a different way of viewing the existing theory and results. La propagation des ondes élastiques est généralement traitée sous quatre hypothèses : - le milieu est isotrope, - le milieu est homogène, - il y a une relation biunivoque entre la tension et la déformation, - les tensions sont reliées d'une façon linéaire aux déformations (et de manière équivalente, les déformations sont reliées d'une façon linéaire aux tensions. En général au moins une de ces hypothèses - et souvent toutes - n'est pas vérifiée dans les milieux réels. Une description théorique valide de la propagation des ondes dans les milieux réels dépend ainsi de la description à la fois qualitative et quantitative de l'hétérogénéité, de l'anisotropie et de la non-linéarité : soit on doit supposer (ou montrer que l'écart par rapport à l'hypothèse de départ peut être - pour le problème considéré - négligé, soit on doit développer une description théorique, valide même en présence de ces écarts. Alors que l'effet d'un seul écart par rapport à un état idéal est relativement bien connu, les difficultés surviennent quand on veut combiner plusieurs de ces écarts. Les propriétés élastiques non linéaires d'échantillons de roche anisotropes (tricliniques ont été étudiées, par P. Rasolofosaon et H. Yin au 6e IWSA à Trondheim (Rasolofosaon et Yin, 1996. L'élasticité anisotrope non linéaire est importante seulement pour les amplitudes

Preserved magnetic fabrics vs. annealed microstructures in the syntectonic recrystallised George granite, South Africa

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Ferré, E. C.; Améglio, L.

2000-08-01

The Saldanian basement of the Cape Fold Belt of South Africa outcrops in the Kaaimans inlier with granite plutons intruded in low-grade pelitic and quartzitic metasediments around 535 Ma. New field data support a ubiquitous Saldanian top-to-the-north thrust kinematics coeval with granite emplacement with no substantial Cape tectonic overprint. The granites and their contact aureoles display both synkinematic and post-kinematic fabrics. This and the high strain zone commonly observed all along the contact between the Kaaimans inlier and the Cape Fold Belt, suggest a structural decoupling between the basement and its cover. Microstructures in the Kaaimans inlier and in the George pluton establish a post-kinematic, pervasive and thermal overprint of Saldanian age. Granites and country rocks record a medium-temperature/high-strain deformation phase followed by a strong low-temperature/static recrystallisation. Two sets of andalusite porphyroblasts occur systematically in the contact aureoles of the studied plutons and cannot be explained by successive magmatic pulses. The granites, studied by the Anisotropy of Magnetic Susceptibility (AMS) technique, are paramagnetic (20law) and on intrinsic mineral susceptibilities. The magnetic foliations and lineations are homogeneous throughout the George pluton and are consistent with field structures. The AMS results mainly from the magneto-crystalline anisotropy of biotite and from its lattice preferred orientation (LPO) in the rock. The magnetic fabric reveals the biotite subfabrics that had been acquired before static recrystallisation and which was not modified by the subsequent thermal metamorphic event. The magnetic fabric therefore preserves the emplacement-related deformation fabric.

George Herbert Mead and the Allen controversy at the University of Wisconsin.

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Cook, Gary A

2007-01-01

This essay uses previously unpublished correspondence of George Herbert Mead to tell the story of his involvement in the aftermath of a political dispute that took place at the University of Wisconsin during the years 1914-1915. It seeks thereby to clarify the historical significance of an article he published on this controversy in late 1915. Taken together with relevant information about the educational activities of William H. Allen of the New York Bureau of Municipal Research, Mead's correspondence and article throw helpful light upon his understanding of how an educational survey of a university should proceed; they also show how he went about the task of evaluating a failed attempt at such a survey. (c) 2007 Wiley Periodicals, Inc.

Guerra, ejército y militares en la vida y el pensamiento de George Santayana

OpenAIRE

Arias González, Luis

2016-01-01

George Santayana’s life (1863-1952) and thought, constitute in themselves a fundamental historical event and also represent a crucial period in history. The present article analyses Santayana’s vision of the war as a phenomenon and also the role played by the Military Forces in Society. The article also explains his positioning with respect to the wars which took place in his days: The Cuban War, The First World War and the Spanish Civil War. On the other hand, a reconstruction of his family...

Sosiaalipsykologian sydän : George H. Mead ja symbolinen interaktionismi sosiaalipsykologian tutkimustraditioissa ja toimijuuden teoriassa

OpenAIRE

Hankamäki, Jukka Sakari

2016-01-01

In this study my aim is to clarify George H. Mead’s (1863–1931) impact history and his significance for the development of social psychology. Another task is to systematically analyse the problems and paradoxes faced by Mead in his theory of meaning and concept of the human being. The third target is to draw a holistic theory of human being for the needs of present social psychology and the theory of agency. My approach is philosophical and epistemological, and my method is hermeneutical,...

The effects of child abuse as seen in adults: George Orwell.

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Shengold, L

1985-01-01

The author presents the case of a patient who showed the massive defensive effects seen in people who were abused in childhood. These effects are similar to those described in George Orwell's 1984 and in his autobiographical writings: denial and "doublethink"; masochistic submission to the tormentor; turning of anger against the self and loving "Big Brother"; identifying with the abuser and tormenting others; a burgeoning of anal mechanisms and obsessive phenomena that results in a massive isolation of affects; excessive emotional control alongside outbursts of rage. The interference with memory and emotions compromises identity and humanity. The unforseeable evolution of innate gifts in a child sometimes permits a partial transcendence of these crippling defenses, as Orwell partially transcended what appears to have been the emotional deprivation of his childhood and what he felt to have been the abuse of his schoolboy years.

Treatment of singultus by sexual stimulation: Who was George T Dexter, MD (c1812-?)?

Science.gov (United States)

Petroianu, Georg A

2016-05-01

This short report attempts to shed light on the interesting but controversial personality of George T Dexter (ca1812 -?), the physician who first described manipulation of the female genitalia in a hysterical impressionable girl as being associated with the termination of singultus. Although his interaction with the young female patient would not meet today's ethical standards, his medical observation was valid and contributes to our understanding of the pathophysiology of singultus. He was well ahead of his colleagues who presented hiccup therapy case reports with similar or related pathophysiology mechanisms some 150 years later. © IMechE 2014.

Social Reconstructionist Philosophy of Education and George S. Counts: Observations on the Ideology of Indoctrination in Socio-Critical Educational Thinking

Science.gov (United States)

Sutinen, Ari

2014-01-01

This article comprises three parts: The author first outlines the principles of the social reconstructionist philosophy of education related to educational activity and social philosophy. After this, he describes the educational philosophy of George S. Counts, the most important developer of the social reconstructionist philosophy of education,…

Monitoring of populations and productivity of seabirds at St. George Island, Cape Peirce, and Bluff, Alaska, 1989. Final report

International Nuclear Information System (INIS)

Mendenhall, V.M.

1991-04-01

In recent years, although descriptive studies have continued, the emphasis on population monitoring of seabirds has increased. Commercial uses of the Continental Shelf of the Bering and Chukchi Seas, including oil and gas development, subsurface placer mining, and commercial fishing, carry the potential for adverse pressures on seabird populations. Populations and productivity of seabirds were monitored in 1989 at three Bering Sea colonies: St. George, Cape Peirce, and Bluff. Murres and black-legged kittiwakes were monitored at all colonies to facilitate intercolony comparisons. These species were selected because they are relatively easy to study, numerous, sensitive to potential impacts of development, and widely distributed. Red legged kittiwakes also were monitored at St. George because of concern for the world status of the species. Methods were standardized among the three colonies to facilitate comparisons among colonies and years. Observations of productivity began at the time nests were established and continued until most young had fledged. Kittiwake nests and murre breeding sites used for estimation of productivity were mapped on photographs or sketches and the fate of each was recorded

La gamba di Tamerlano. Contestualizzazione del sintomo e prospettiva metaculturale nell’etnopsichiatria di Georges Devereux

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Viola Carofalo

2014-06-01

Full Text Available The aim of the reflection of Georges Devereux is the establishment of a therapeutic practice in the ethnopsychiatric field, based on the complementary idea of the Danish mathematician Niels Bohr. This article will show how Devereux applies this principle to the studies on mental illness suffered by the Plains Indian during the mid-fifties, using his skills in the fields of anthropology and psychoanalysis. It will give a special attention to the case of Jimmy Picard, the main character of the famous essay Reality and dream: Psychotherapy of a Plains Indian.

The contributions of the music of George Fenton to the fi lms of Ken Loach

OpenAIRE

Sofía López Hernández

2018-01-01

Ken Loach is a high profile British film director. Since the mid 1960’s, he has made numerous films for cinema and television. There is already a lot written about his way of filming and yet very little is written about the music for his films. To be able to get inside the music of Ken Loach’s films, we must first talk about George Fenton as he has been Loach’s usual composer since 1994. The object of this article is to fill this gap: to discover what musical characteristics Fenton contri...

O erotismo e o sagrado no livro A história do olho de George Bataille

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Silvane Santos SOUZA

2016-07-01

Full Text Available This article aims to discuss one of George Bataille thoughts, from the analysis of the erotic novel Story of the eye, one of his most outstanding works. The History of the eye is filled with narrative scenes where the image of the eye is seen as a transfigurável object. In this book, Bataille argues heterogeneous when discussing topics such as eroticism and sacred, addressed a vision that opposes the discourse of a bourgeois society that preaches what is homogeneous, showing from the erotic scenes confrontation to “normality” of the society of the time, with the presentation of situations to a certain surreal point, endowed with transgression. Thus, the discussion points out that the work of Bataille seeks to repudiate the issues taken for granted essentially on eroticism and sexuality, as the latter is stated as unproductive expenditure, overspending and completely sterile, because sex is not presented as source of relief or satiety but as a great distress. A milestone that distinguishes the work is the relationship between sexuality, sacred and eroticism, going beyond simple sexual adventure, for the pursuit of “orgasm” through the eye imagery. To discuss these issues, the ideas presented here are backed up in the following authors: George Bataille, Barthes, Wasghinton Drumonnd, Jürgen Habermas, Philippe Joron, Michel Leiris and Eliane Moraes.

Stepwise dissection and visualization of the catalytic mechanism of haloalkane dehalogenase LinB using molecular dynamics simulations and computer graphics.

Science.gov (United States)

Negri, Ana; Marco, Esther; Damborsky, Jiri; Gago, Federico

2007-10-01

The different steps of the dehalogenation reaction carried out by LinB on three different substrates have been characterized using a combination of quantum mechanical calculations and molecular dynamics simulations. This has allowed us to obtain information in atomic detail about each step of the reaction mechanism, that is, substrate entrance and achievement of the near-attack conformation, transition state stabilization within the active site, halide stabilization, water molecule activation and subsequent hydrolytic attack on the ester intermediate with formation of alcohol, and finally product release. Importantly, no bias or external forces were applied during the whole procedure so that both intermediates and products were completely free to sample configuration space in order to adapt to the plasticity of the active site and/or search for an exit. Differences in substrate reactivity were found to be correlated with the ease of adopting the near-attack conformation and two different exit pathways were found for product release that do not interfere with substrate entrance. Additional support for the different entry and exit pathways was independently obtained from an examination of the enzyme's normal modes.

George Guthrie's clinical trial at the Napoleonic War Battle of Toulouse in 1814.

Science.gov (United States)

Malhan, Neeraj K; Greenslade, Tessa; Mitchell, Piers D

2009-08-01

George James Guthrie (1785-1856) was a British military surgeon who came to prominence during the Napoleonic Wars (1803-15). He wrote several books on military surgery and was President of the Royal College of Surgeons of England three times. However, his most innovative and important achievement has largely gone unrecognised by modern historians. In 1814, at the battle of Toulouse in the Peninsular Campaign, he performed a landmark early trial of the treatment of musket wounds to the thigh. Here we not only discuss this clinical trial and place it in its social context, but also present the pathological skeletal specimens of two wounded British soldiers who took part in it.

Ernst Mach and George Sarton's Successors: The Implicit Role Model of Teaching Science in USA and Elsewhere, Part II

Science.gov (United States)

Siemsen, Hayo

2013-01-01

George Sarton had a strong influence on modern history of science. The method he pursued throughout his life was the method he had discovered in Ernst Mach's "Mechanics" when he was a student in Ghent. Sarton was in fact throughout his life implementing a research program inspired by the epistemology of Mach. Sarton in turn inspired many…

Education in Time of War: George Johnson and the Commission on American Citizenship of the Catholic University of America

Science.gov (United States)

Elias, John L.

2009-01-01

Times of war are times of crisis for theologians and educators. This article examines how Msgr. George Johnson, the vice president of the Religious Education Association and the most prominent Catholic educator in the 1930s and 1940s, dealt with the ethical and educational issues surrounding U.S. involvement in the Second World War. It argues that…

George Orwell's Animal Farm: A metonym for a dictatorship

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H. Sewlall

2002-08-01

Full Text Available George Orwell’s Animal Farm is traditionally read as a satire on dictatorships in general, and the Bolshevik Revolution in particular. This article postulates the notion that the schema of the book has attained the force of metonymy to such an extent that whenever one alludes to the title of the book or some lines from it, one conjures up images associated with a dictatorship. The title of the book has become a part of the conceptual political lexicon of the English language to refer to the corruption of a utopian ideology. As an ideological state, Animal Farm has its vision, which is embedded in its constitution; it has the vote, a national anthem and a flag. It even has its patriots, double-dealers, social engineers and lechers. In this way the title Animal Farm, like Joseph Heller’s Catch-22, or Thomas More’s Utopia, functions metonymically to map a conceptual framework which matches the coordinates of the book. The article concludes with a look at contemporary society to show how Orwell’s satire endorses the words of Lord Acton, namely, that power corrupts and absolute power corrupts absolutely.

A sociohistorical examination of George Herbert Mead's approach to science education.

Science.gov (United States)

Edwards, Michelle L

2016-07-01

Although George Herbert Mead is widely known for his social psychological work, his views on science education also represent a significant, yet sometimes overlooked contribution. In a speech delivered in March 1906 entitled "The Teaching of Science in College," Mead calls for cultural courses on the sciences, such as sociology of science or history of science courses, to increase the relevancy of natural and physical science courses for high school and university students. These views reflect Mead's perspective on a number of traditional dualisms, including objectivity versus subjectivity and the social sciences versus natural and physical sciences. Taking a sociohistorical outlook, I identify the context behind Mead's approach to science education, which includes three major influences: (1) German intellectual thought and the Methodenstreit debate, (2) pragmatism and Darwin's theory of evolution, and (3) social reform efforts in Chicago and the General Science Movement. © The Author(s) 2014.

The founder of the church of Saint George at Pološko

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Pavlović Dragana

2015-01-01

Full Text Available The paper seeks to establish who was the founder of the church of Saint George at Pološko and revise the conclusions of previous researchers regarding this issue. According to the opinion commonly adopted in the scholarly literature, Jovan Dragušin, a cousin of King Dušan, had merely undertaken the construction of church at Pološko, whereas his mother was responsible for the completion of construction and painting of frescoes in the church. Through an analysis of written and visual sources the conclusion is reached that the sole person responsible for the construction and painting of the church at Pološko was the nun Maria, the mother of Jovan Dragušin. [Projekat Ministarstva nauke Republike Srbije, br. 177036: Srpska srednjovekovna umetnost i njen evropski kontekst

NRC closing remarks

International Nuclear Information System (INIS)

Coffman, F.

1994-01-01

This section contains the edited transcript of the NRC closing remarks made by Mr. Franklin Coffman (Chief, Human Factors Branch, Office of Nuclear Regulatory Research) and Dr. Cecil Thomas (Deputy Director, Division of Reactor Controls and Human Factors, Office of Nuclear Reactor Regulation). This editing consisted of minimal editing to correct grammar and remove extraneous references to microphone volume, etc

Etude de la stabilité globale de l’équilibre endémique des modèles multi groupes SIR avec une incidence non linéaire.

OpenAIRE

BENCHAIB, NESRINE

2014-01-01

Dans ce mémoire, on présente le nombre de reproduction de base pour un modèle épidémique multigroupe avec une incidence non linéaire. Ensuite, on établie la dynamique globale est entièrement déterminée par le nombre de reproduction de base R0. On montre que le nombre de reproduction de base R0 est un paramètre global de seuil dans le sens que si il est inférieur ou égale à 1, l’équilibre sans maladie est globalement stable et la maladie s’éteint, alors que si il est supérieur à 1, il est u...

Source apportionment of PM2.5 at the Lin'an regional background site in China with three receptor models

Science.gov (United States)

Deng, Junjun; Zhang, Yanru; Qiu, Yuqing; Zhang, Hongliang; Du, Wenjiao; Xu, Lingling; Hong, Youwei; Chen, Yanting; Chen, Jinsheng

2018-04-01

Source apportionment of fine particulate matter (PM2.5) were conducted at the Lin'an Regional Atmospheric Background Station (LA) in the Yangtze River Delta (YRD) region in China from July 2014 to April 2015 with three receptor models including principal component analysis combining multiple linear regression (PCA-MLR), UNMIX and Positive Matrix Factorization (PMF). The model performance, source identification and source contribution of the three models were analyzed and inter-compared. Source apportionment of PM2.5 was also conducted with the receptor models. Good correlations between the reconstructed and measured concentrations of PM2.5 and its major chemical species were obtained for all models. PMF resolved almost all masses of PM2.5, while PCA-MLR and UNMIX explained about 80%. Five, four and seven sources were identified by PCA-MLR, UNMIX and PMF, respectively. Combustion, secondary source, marine source, dust and industrial activities were identified by all the three receptor models. Combustion source and secondary source were the major sources, and totally contributed over 60% to PM2.5. The PMF model had a better performance on separating the different combustion sources. These findings improve the understanding of PM2.5 sources in background region.

The murine homologue of HIRA, a DiGeorge syndrome candidate gene, is expressed in embryonic structures affected in human CATCH22 patients

NARCIS (Netherlands)

L.G. Wilming (Laurens); C.A. Snoeren; A.L. Rijswijk (Angelique); C. Meijers (Carel); F.G. Grosveld (Frank)

1997-01-01

textabstractA wide spectrum of birth defects is caused by deletions of the DiGeorge syndrome chromosomal region at 22q11. Characteristic features include cranio-facial, cardiac and thymic malformations, which are thought to arise form disturbances in the interactions

George Marinesco in the Constellation of Modern Neuroscience

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Ioan Opris

2017-12-01

Full Text Available George Marinesco is the founder of Romanian School of Neurology and one of the most remarkable neuroscientists of the last century. He was the pupil of Jean-Martin Charcot in Salpêtrière Hospital in Paris, France, but visited many other neurological centers where he met the entire constellation of neurologists of his time, including Camillo Golgi and Santiago Ramón y Cajal. The last made the preface of Nervous Cell, written in French by Marinesco. The original title was “La Cellule Nerveuse” and is considered even now a basic reference book for specialists in the field. He was a refined clinical observer with an integrative approach, as could be seen from the multitude of his discoveries. The descriptions of the succulent hand in syringomyelia, senile plaque in old subjects, palmar jaw reflex known as Marinesco-Radovici sign, or the application of cinematography in medicine are some of his important contributions. He was the first who described changes of locus niger in a patient affected by tuberculosis, as a possible cause in Parkinson disease. Before modern genetics, Marinesco and Sjögren described a rare and complex syndrome bearing their names. He was a hardworking man, focused on his scientific research, did not accepted flattering of others and was a great fighter against the injustice of the time.

George Marinesco in the Constellation of Modern Neuroscience.

Science.gov (United States)

Opris, Ioan; Nestianu, Valeriu S; Nestianu, Adrian; Bilteanu, Liviu; Ciurea, Jean

2017-01-01

George Marinesco is the founder of Romanian School of Neurology and one of the most remarkable neuroscientists of the last century. He was the pupil of Jean-Martin Charcot in Salpêtrière Hospital in Paris, France, but visited many other neurological centers where he met the entire constellation of neurologists of his time, including Camillo Golgi and Santiago Ramón y Cajal. The last made the preface of Nervous Cell, written in French by Marinesco. The original title was "La Cellule Nerveuse" and is considered even now a basic reference book for specialists in the field. He was a refined clinical observer with an integrative approach, as could be seen from the multitude of his discoveries. The descriptions of the succulent hand in syringomyelia, senile plaque in old subjects, palmar jaw reflex known as Marinesco-Radovici sign, or the application of cinematography in medicine are some of his important contributions. He was the first who described changes of locus niger in a patient affected by tuberculosis, as a possible cause in Parkinson disease. Before modern genetics, Marinesco and Sjögren described a rare and complex syndrome bearing their names. He was a hardworking man, focused on his scientific research, did not accepted flattering of others and was a great fighter against the injustice of the time.

Recolonization of gravel habitats on Georges Bank (northwest Atlantic)

Science.gov (United States)

Collie, Jeremy S.; Hermsen, Jerome M.; Valentine, Page C.

2009-09-01

Gravel habitats on continental shelves around the world support productive fisheries but are also vulnerable to disturbance from bottom fishing. We conducted a 2-year in situ experiment to measure the rate of colonization of a gravel habitat on northern Georges Bank in an area closed to fishing (Closed Area II) since December 1994. Three large (0.25 m 2) sediment trays containing defaunated pebble gravel were deployed at a study site (47 m water depth) in July 1997 and recovered in June 1999. The undersides of the tray lids positioned 56 cm above the trays served as settlement panels over the same time period. We observed rapid colonization of the gravel substrate (56 species) and the settlement panels (35 species), indicating that colonization of gravel in this region is not limited by the supply of colonists. The species composition of the taxa found in the trays was broadly similar to that we collected over a 10-year period (1994-2004) in dredge samples from gravel sediments at the same site. The increase in abundance of animals in the gravel colonization trays was rapid and reached a level in 2 years that took 4.5 years to achieve in the surrounding gravel sediments once fishing had stopped, based on data from dredge sampling at this site. The increase in biomass of animals found in the sediment trays paralleled the trend of biomass increase observed in dredge samples over the same period (1997-1999) but was lower in value. These data suggest that after rapid initial increase in abundance of organisms, succession proceeded by increasing individual body size. A comparison of settlement panel and tray faunas revealed that the mean biomass of structure-forming epifauna (sponges, bryozoans, anemones, hydroids, colonial tube worms) on the panels was 8 times that found on the trays. Structure-forming taxa constituted 29% of the mean biomass of the panel fauna but only 5.5% of the tray fauna. By contrast, the mean biomass of scavengers (crabs, echinoderms, nudibranchs

Recolonization of gravel habitats on Georges Bank (northwest Atlantic)

Science.gov (United States)

Collie, Jeremy S.; Hermsen, Jerome M.; Valentine, Page C.

2009-01-01

Gravel habitats on continental shelves around the world support productive fisheries but are also vulnerable to disturbance from bottom fishing. We conducted a 2-year in situ experiment to measure the rate of colonization of a gravel habitat on northern Georges Bank in an area closed to fishing (Closed Area II) since December 1994. Three large (0.25 m2) sediment trays containing defaunated pebble gravel were deployed at a study site (47 m water depth) in July 1997 and recovered in June 1999. The undersides of the tray lids positioned 56 cm above the trays served as settlement panels over the same time period. We observed rapid colonization of the gravel substrate (56 species) and the settlement panels (35 species), indicating that colonization of gravel in this region is not limited by the supply of colonists. The species composition of the taxa found in the trays was broadly similar to that we collected over a 10-year period (1994-2004) in dredge samples from gravel sediments at the same site. The increase in abundance of animals in the gravel colonization trays was rapid and reached a level in 2 years that took 4.5 years to achieve in the surrounding gravel sediments once fishing had stopped, based on data from dredge sampling at this site. The increase in biomass of animals found in the sediment trays paralleled the trend of biomass increase observed in dredge samples over the same period (1997-1999) but was lower in value. These data suggest that after rapid initial increase in abundance of organisms, succession proceeded by increasing individual body size. A comparison of settlement panel and tray faunas revealed that the mean biomass of structure-forming epifauna (sponges, bryozoans, anemones, hydroids, colonial tube worms) on the panels was 8 times that found on the trays. Structure-forming taxa constituted 29% of the mean biomass of the panel fauna but only 5.5% of the tray fauna. By contrast, the mean biomass of scavengers (crabs, echinoderms, nudibranchs

The human and the inhuman: visual culture, political culture, and the images produced by George Rodger and Henri Cartier-Bresson in the Nazi concentration camps

Directory of Open Access Journals (Sweden)

Erika Cazzonatto Zerwes

2016-08-01

Full Text Available This article aims to grasp some aspects of the notion of humanism in photography and its closeness to the political culture and the visual culture in the period, through the specific experiences of George Rodger and Henri Cartier-Bresson, two photographers who were first-hand witnesses and provided accounts of horror in the Nazi concentration camps at the end of World War II. George Rodger photographed the Bergen-Belsen camp as soon as it was liberated by the British troops. Henri Cartier-Bresson was there with a film crew recording the deported masses newly freed from the Nazi concentration and extermination camps. These experiences came to have profound impact on the biography and work of both of them. In the two cases, there is a notion of humanism linked to World War II events, which is observed in photography and photographic representation, and it has a significant consequence for the contemporary visual culture.   Keywords: Visual Culture; Political Culture; War Photography; Photojournalism; Concentration Camps.   Original title: O humano e o desumano: cultura visual, cultura política e as imagens feitas por George Rodger e Henri Cartier-Bresson nos campos de concentração nazistas.

A via analógica no pensamento de Georg Simmel

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Lenin Bicudo Bárbara

2015-04-01

Full Text Available In this paper I deal with the role of analogical reasoning in the thought of Georg Simmel (1858-1918, one of the founders of German sociology. My main goal here is to grasp the relations between analogy-making as a cognitive resource and the style of thought to which Simmel clings. As a first step towards this, I gather the fragments of the history of the concept of analogy that I consider to be the most relevant to Simmel’s reception of it. After that, I put forward a synoptic survey of the instances of analogy that can be identified in those of his works deemed to be the most influential to sociology, viz., his Philosophie des Geldes (1900 and his Soziologie (1908. Finally, I face the question regarding how Simmel handled his analogies as he set out to articulate such intellectual undertakings – aiming to lay bare the connections between this resource and the cognitive ideal of plasticity, conceived as a pervasive guiding principle of Simmel’s sociological and philosophical thought.

MEMBEDAH TEORI SOSIOLOGI: Teori Pertukaran (Exchange Theory George Caspar Homans

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Wardani Wardani

2016-05-01

Full Text Available This article is aimed at analyzing critically George Caspar Homans’s theory of exchange. The critical analysis that may be called here simply as “maping ideology” embodied in theory is needed to place the theory within the specific social and political condition, intellectual background, school of thought having great influence on it, and so forth, and also to assesses its limitedness as a theoretical frame-work of scientific research to explain complicated social phenomenon or human interaction. Influenced by psychological and economic theories, Homans’s theory of exchange has been intended at the beginning by the author as attack against Marxism domination that addressed criticism to capitalism as macro-structure oppressing the proletariat by the ruling class and against Durkheimian structural functionalism. By addressing the attack against Marxism and because of his intellectual and social background, Homans’s theory then has been regarded as an explanation justifying the existing situation. Being attributed as psychological reductionism, as neglecting the important role of structure, and deterministic are some of the objections addressed to his theory.

Paralytic shellfish toxins in the sea scallop Placopecten magellanicus on Georges Bank: Implications for an offshore roe-on and whole scallop fishery

Science.gov (United States)

DeGrasse, Stacey; Vanegas, Camilo; Conrad, Stephen

2014-05-01

To protect public health from the potential risk of paralytic shellfish poisoning (PSP) in sea scallops, Placopecten magellanicus, from the Atlantic offshore U.S. waters of Georges Bank, harvesting of roe-on or whole scallops is banned. Only adductor muscles may be sold if harvested from Georges Bank, Gulf of Maine, or the PSP closure areas as far west as 71° West Longitude. Given the limited toxicity data available for sea scallops from this region both prior to and subsequent to implementation of this management strategy, this study sought a more extensive spatial and temporal evaluation of sea scallop gonad and viscera toxicities that would inform management decisions related to the roe-on and whole scallop fishery. Both overall toxicity and toxin composition were measured for sea scallop gonads and viscera collected from 232 stations in 2007 and 23 in 2010. Overall toxicity was assessed using two screening methods: field-deployable Jellett Rapid Tests (JRT) and quantitative, laboratory-based receptor binding assays (in 2007). Additionally, a quantitative liquid chromatography with fluorescence detection (LC-FD) method was used to determine toxin composition and overall toxicity (in 2010). The at-sea qualitative JRT screening tool results, whereby a positive indicated the sample contained at least 40 μg saxitoxin (STX) equivalents 100 g-1, were often inconsistent with results obtained using the quantitative methods. Sea scallop viscera toxicity represented the majority of toxin load in the organism and was often in excess of the regulatory guidance level. Sea scallop gonads accounted for a small percentage of total toxicity, but at times reached unsafe levels. Toxin composition in both the gonads and viscera was dominated by STX and gonyautoxin 2/3, as has been reported in previous studies. No predictive indices of gonad toxicity were found. Results at this time do not support a roe-on or whole scallop fishery on Georges Bank. While access restrictions to

Recovering and Framing the George I. Sanchez Legacy of Chicana/o Student and Policy Advocacy: Utilizing Data for Social Change

Science.gov (United States)

Rodríguez, Cristóbal

2014-01-01

Recovering and critically examining the pioneering scholarship and history of George I. Sanchez provides an interpretation toward a legacy of a Chicana/o student and policy advocacy framework for Chicana/o scholars to consider. The author of this work applies a critical policy theoretical analysis by Frank Fischer to develop a Chicana/o student…

Social Movements Against Racist Police Brutality and Department of Justice Intervention in Prince George's County, Maryland.

Science.gov (United States)

Hutto, Jonathan W; Green, Rodney D

2016-04-01

Racist police brutality has been systemic in Prince George's County, Maryland. The victims include African Americans, the mentally challenged, and immigrant populations, creating a complex and uneven public health impact. Three threads characterize the social movements and intervention since 1970. First, a significant demographic shift occurred as African Americans became the majority population in the late 1980s when the first Black county executive was elected in 1994. Despite the change in political leadership, police brutality remained rampant. Lower-income households located close to the District of Columbia and "inside the beltway" experienced the most police brutality. In 2001, The Washington Post revealed that between 1990 and 2000, Prince George's police shot and killed more citizens per officer than any of the 50 largest city and county law enforcement agencies in the country, 84 % of whom were black. Of the 147 persons shot during the 1990s, 12 were mentally and/or emotionally disturbed; 6 of these shootings were fatal. Second, resistance to police brutality emerged in a variety of political formations throughout the period, especially in the late 1990s. Sustained community pressure prompted the Department of Justice (DOJ) to open a civil rights investigation of the police department in November 2000. To avoid a potential federal lawsuit, the county leadership negotiated a memorandum of agreement (MOA) with the DOJ to enact policy reforms, part of which called for supplementing the departmental mobile crisis team, comprised of mental health care professionals, to respond to all cases involving mentally challenged citizens. Third, the incomplete process of change subsequent to the ending of DOJ oversight suggests a continued challenge to social movements opposing police brutality. This study focuses on the effectiveness of the MOA along with the activism of the People's Coalition for Police Accountability (PCPA) in reforming a culture of police brutality

[PhD theses at the University of Tartu/Dorpat supervised by Georg Dragendorff 1864-1894].

Science.gov (United States)

Hinrikus, T; Tankler, H; Raal, A

2005-05-01

During 30 years, the professor of pharmacy Georg Dragendorff (1836-1898), who had been invited from Germany, supervised 90 theses of Master of Pharmacy and 87 theses of Doctor of Medicine in Tartu/Dorpat. The present article discusses the authors of these theses, Dragendorff and his co-operation with other university lecturers, the structure of the theses and the regulations of the thesis defence. Analysis of the contents of the theses revealed extensive contacts of the pharmacy of the time with different fields of science. Dragendorff as the supervisor of these theses contributed much to the training of physicians.

Larval trophodynamics, turbulence, and drift on Georges Bank : A sensitivity analysis of cod and haddock

DEFF Research Database (Denmark)

Werner, F.E.; MacKenzie, Brian; Perry, R.I.

2001-01-01

Using an individual-based model approach we consider trophodynamic effects on the growth and survival of larval cod (Gadus morhua) and haddock (Melanogrammus aeglefinus) on Georges Bank during late winter/early spring. These studies represent an extension of results described in Werner et al. (1996...... be an important input to larval growth and survival models. The inclusion of turbulence in determining the position of passive larvae in the water column allows the larvae to sample the entire water column, contributing to a decrease in the variance of the size of the larvae over time. The ability of larvae...

The contributions of the music of George Fenton to the fi lms of Ken Loach

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Sofía López Hernández

2018-01-01

Full Text Available Ken Loach is a high profile British film director. Since the mid 1960’s, he has made numerous films for cinema and television. There is already a lot written about his way of filming and yet very little is written about the music for his films. To be able to get inside the music of Ken Loach’s films, we must first talk about George Fenton as he has been Loach’s usual composer since 1994. The object of this article is to fill this gap: to discover what musical characteristics Fenton contributes to Loach’s cinema.

La Renta de la Tierra en el Pensamiento de J.S. Mill y H. George

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Alberto José Figueras

2008-12-01

Full Text Available El año 2008 ha visto a la sociedad argentina enfrascada en un debate sobre los impuestos a las exportaciones agrícolas. Uno de los puntos centrales fue quién soportaría finalmente el costo de este tributo, su impacto sectorial, grupal y territorial. Ahora bien, cuando surgen estas controversias suele ser útil mirar hacia atrás para descubrir qué fue lo que opinaron los grandes autores del pasado en circunstancias similares, mutatis mutandi. Se revisan ideas y pensamientos de William Petty, Adam Smith, Henry George , David Ricardo y John Stuar Mill entre otros.

Autonomy and hierarchy in two slave communities: the cases of George (Alabama, United States, 1847 and Lino (Vassouras, Brazil, 1871

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Fábio Pereira de Carvalho

2013-06-01

Full Text Available This article seeks argue that the search for autonomy among slaves necessarily created hierarchies within the community where they were inserted. Through two cases compared, George in U.S. and Lino in Brazil, seeks to show that a notion of slave community was built by the social actors who were part of it

Final Environmental Impact Statement. Disposal and Reuse of George Air Force Base, California. Volume 2. Public Comments and Responses, Appendices

Science.gov (United States)

1992-03-01

mbemehim ~du feildes Twoa 9.9 93~ Imposes GaO meji amy Imo eaudepoGa eaadeeedaus of ,eadaed at ueme G mu gdauw asadarnasimn hi Gam0’ Tbe I* bkt iddea...Southwest Gas Corporation The Nature Conservancy The Sun D-12 George AFO Disposal and Reuse FEIS Unlversky o Callornim Los Angels (uCLA) URS Consultads Vector

Pragmatism, Activism, and the Icy Slopes of Logic in George Reisch's Portrait of the Philosophy of Science as a Young Field

Science.gov (United States)

Stump, David J.

2009-01-01

This paper considers several models of politically engaged philosophy with the aim of provoking discussion of George Reisch's "How the Cold War Transformed Philosophy of Science." At issue is the Unity of Science movement's conception of the philosophy of science in particular and what politically engaged philosophy of science might look…

Redefining the Subject, Redefining the Social, Reconsidering Education: George Herbert Mead's Course on Philosophy of Education at the University of Chicago.

Science.gov (United States)

Biesta, Gert J. J.

1999-01-01

George Mead's posthumously published works express a genuine philosophy of education. This paper contributes to the reconstruction of Mead's educational philosophy, examining a typescript of student notes from his course on philosophy of education at the University of Chicago. The essay discusses the typescript against the backdrop of Mead's…

A Reassessment of George Pierce Baker's "The Principles of Argumentation": Minimizing the Use of Formal Logic in Favor of Practical Approaches

Science.gov (United States)

Bordelon, Suzanne

2006-01-01

In this article, the author demonstrated how recent histories relied primarily on previous accounts and one textbook to characterize George Pierce Baker's work. This narrow assessment of "The Principles of Argumentation" limits one's understanding of his contribution to argumentation theory and pedagogy. Similarly, one has seen the need for care…

The church Saint-Symphorien in Nuits-Saint-Georges. An architectural and decorative syncretism, ca 1220-1240

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Sylvain Demarthe

2011-12-01

Full Text Available Saint Symphorian’s church in Nuits-Saint-Georges (Burgundy, which dates from near 1220-1240, is situated during the transition of two architectural styles and attests a local but rather backward-looking Cistercian legacy that some Gothic urban and more innovative elements modernize. Moreover the church takes part, for the same reasons as those in Agencourt, Gerland and Prissey, in the surprising wave of reconstructions which denotes among others the important economic development of the country of Cîteaux at the beginning of the 13th century.

Occurrence of organochlorine pesticides in the environmental matrices from King George Island, west Antarctica

International Nuclear Information System (INIS)

Zhang, Qinghua; Chen, Zhaojing; Li, Yingming; Wang, Pu; Zhu, Chaofei; Gao, Guanjun; Xiao, Ke; Sun, Huizhong; Zheng, Shucheng; Liang, Yong; Jiang, Guibin

2015-01-01

Antarctica is considered as a final sink of many persistent organic pollutants (POPs). This work aims to investigate the levels, distributions and potential sources of organochlorine pesticides (OCPs) with HRGC/HRMS technique. Twenty-three OCPs were measured in various environmental matrices from King George Island, west Antarctica. The total concentrations (Σ_2_3OCPs) were at quite low levels, ranging 93.6–1260 pg g"−"1 dry weight (dw) in soil and sediment, 223–1053 pg g"−"1 dw in moss and 373–812 pg g"−"1 dw in lichen. Hexachlorobenzene (HCB), dichloro-diphenyl-trichloroethane (DDT) and its metabolites (especially p,p′-DDE) and hexachlorocyclohexanes (HCHs) were the main contaminants in all samples. Lower α-HCH/γ-HCH and higher p,p′-DDE/p,p′-DDT ratios compared with the technical products indicated long-range atmospheric transport (LRAT) of recent lindane and aged technical DDT. Significant dependence of many OCPs concentrations on total organic carbon (TOC) was observed. Apart from LRAT, local biotic activities could also contribute and influence the spatial distribution of the contaminants. - Graphical abstract: Map of King George Island, west Antarctica and Σ_2_3OCPs levels based on TOC (pg g"−"1 TOC) vs. dry weight (pg g"−"1 dw) in the soil and sediment samples. - Highlights: • Twenty-three OCPs were investigated in various matrices from Antarctica by HRGC/HRMS. • OCPs concentrations were at quite low levels in soils, sediments, mosses and lichens. • HCB and p,p′-DDE were dominant contributors of the total OCPs concentration. • Higher OCPs levels were found in the dropping-amended soil than natural soil. • The sources of HCHs, DDTs and chlordane compounds (CHLs) were discussed. - Occurrence and sources of OCPs in soil and terrestrial vegetation from west Antarctica were investigated.

The ‘Brutalization’ Thesis (George L. Mosse and its Critics: A Historiographical Debate | La tesis de la brutalización (George L. Mosse y sus críticos: un debate historiográfico

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Ángel Alcalde

2016-12-01

Full Text Available This article explores the widespread international debate in modern historiography maintained around the “brutalization” thesis, which was popularized in George L. Mosse’s book Fallen Soldiers (1990. According to Mosse, the war experience of the front soldiers during World War I was the cause of the heightened levels of political violence during the Weimar Republic. Such brutalization allegedly provided the basis for Nazism and the Genocide. In an attempt to clarify the origins of Mosse’s interpretation this work analyses criticism, reformulations and uses of “brutalization”. In spite of the fact that the heated debate reached no consensus, it eventually managed to establish a revealing –though vague and scarcely open to analytical potential notion in the professional language of historians. | Este artículo explora el amplio debate internacional mantenido por historiadores contemporaneístas en torno a la tesis de la “brutalización”, popularizada por George L. Mosse a partir de su libro Soldados caídos (1990, y según la cual la experiencia de guerra de los soldados del frente en la Primera Guerra Mundial habría sido la causa de los altos niveles de violencia política de la República de Weimar y, por ende, el origen del nacionalsocialismo y el genocidio. El artículo clarifica las raíces de la interpretación mosseana, analiza las críticas, reformulaciones y usos de la “brutalización” y concluye que el fuerte debate mantenido, a pesar de no alcanzar consenso, terminó por consagrar una noción sugerente, aunque obscura y de cuestionable capacidad analítica, en el lenguaje profesional de los historiadores.

Evaluación preclínica y estudio de estabilidad de extractos a partir del follaje de Momordica charantia Lin

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A. Lagarto

2014-12-01

Full Text Available El objetivo del presente trabajo fue la evaluación preclínica y el estudio de estabilidad de extractos a partir del follaje de Momordica charantia Lin. Se obtuvieron extractos acuoso e hidroalcohólico para los cuales se establecieron las especificaciones de calidad mediante la evaluación de tres lotes y se estudió su estabilidad por el método de vida de estante durante 12 meses. A los extractos se le evaluó el potencial genotóxico mediante ensayos de micronúcleos en médula ósea de ratón y aberraciones cromosómicas en linfocitos de sangre periférica. La actividad hipoglicemiante oral fue evaluada en animales con hiperglicemia temporal inducida por carga de glucosa. Como resultados se establecieron las especificaciones de calidad de los extractos acuoso e hidroalcohólico, los mismos mostraron estabilidad por 6 meses para el extracto acuoso y 12 meses para el extracto hidroalcohólico. No mostraron efecto genotóxico en los ensayos evaluados y mostraron efecto hipoglicemiante oral a la dosis de 450 mg/kg.

Di sfondo e allo specchio. L’antropologia religiosa di Georg Simmel - There in the background and in the mirror. George Simmel's religious anthropology

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Mariachiara Spagnolo

2015-11-01

Full Text Available The aim of this article is to highlight some shadowed perspectives contained in the Collected Essays on the Sociology of Religion, which include the works published by Georg Simmel from 1898 to 1918, year of the philosopher’s death. Other writings of the Author are used for comparison, or to explain the evolution of the Simmelean thought, or its unravelling in expositive analyses in which the role of religion, or spirituality, is not as decisive as in the essays published in 1906, and later in 1912 (Die Religion. Here religion and spirituality complement a worldview whose connections between art/religion/spiritualism, or those of a symbolism between goods/subjects/individual and society, merge also into unexpected religious manifestations, which are not, however, oriented towards an image that can be defined or centred by means of a strictly religious order or frame. An analysis of Simmel’s texts reveals that religion is also composed of an inventory with unlimited non-catalogued possibilities: human and religious representations do not dismantle the sentiment/impulse that stirs them; rather they arrest it in one of the many ‘forms’ of the possible reality, which is always re-combinable and always knowable. Keywords: Religion, spiritualism, goods, religious representations

Georg Simmel, une interprétation critique de la notion kantienne du bonheur.

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Annette Disselkamp

2004-04-01

Full Text Available Dans un texte relativement peu connu, intitulé Kant, Georg Simmel développe des réflexions critiques à propos de la notion kantienne du bonheur. En comparant celles-ci avec son analyse de la société moderne, telle qu’il la propose dans la Philosophie de l’argent, on s’aperçoit qu’il existe, entre les concepts philosophiques qui y sont mis en œuvre, une relation de correspondance parfaite. La conclusion s’impose que, pour Simmel, la notion kantienne du bonheur trouve comme son incarnation historique dans la culture monétaire. La modernité, que Simmel caractérise par le fait qu’elle offre aux individus la possibilité d’accéder aux objets et aux positions de leur choix, matérialise en effet une aporie inhérente au concept du bonheur chez Kant, dans la mesure où ce dernier souligne l’indétermination totale des choix, d’un côté, et de l’autre, l’idée que c’est hors de la volonté elle-même que la recherche du bonheur puise ses mobiles.In his relatively unknown text Kant, Georg Simmel develops some critical thoughts concerning Kant’s notion of happiness. The comparison between this text and his analysis of modern society, especially in his work Philosophy of Money, reveals that there exists a perfect correspondence between the philosophical concepts used in the two books. This leads us to conclude that, in Simmel’s eyes, monetary culture represents some kind of historical embodiment of the Kantian notion of happiness. Modernity, which offers all individuals the possibility of acquiring any objects or positions they choose, materialises an aporia inherent in Kant’s concept of happiness, consisting in the fact that, on the one hand, our choices are totally undetermined, and, on the other hand, the search for happiness is motivated by impulsions that lie outside of our will.

Depth, temperature, oxygen and salinity profile data from repetitive occupation of a hydrographic station off St. George's, Bermuda from 1954 through 1984 (NODC Accession 0000650)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — CTD, bottle, and other data were collected from the PANULIRUS and other platforms from repetitive occupations of a hydrographic station off St. George's, Bermuda....

Organismo e função reguladora: determinações do vivo em Georges Canguilhem = Organism and regulatory function: determinations of the living in Georges Canguilhem

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Labrea, Vanessa Nicola

2015-01-01

Full Text Available O artigo compreende o cerne da obra de Georges Canguilhem (1904-1995 como um ponto de cruzamento entre problemáticas fundamentalmente médico-biológicas e problemáticas sócio-políticas. A consideração histórica descontinuísta do desenvolvimento de conceitos científicos e a classificação da técnica enquanto prótese do organismo vivo, entre outras particularidades, situam o pensamento canguilhemeano na fronteira entre áreas do conhecimento demarcadas separadamente. O que integra e individualiza o seu trabalho filosófico é a ponderação do vital enquanto categoria de base para intelecção e reconstrução de problemas interdisciplinares. Após indicar o posicionamento de Canguilhem dentro do quadro da filosofia francesa do século XX, o artigo procura demonstrar de que maneira a função de regulação é um dos pilares organizadores do pensamento do “vivo” (le vivant em sua obra

[Archaeal diversity in permafrost deposits of Bunger Hills Oasis and King George Island (Antarctica) according to the 16S rRNA gene sequencing].

Science.gov (United States)

Karaevskaia, E S; Demchenko, L S; Demidov, N É; Rivkina, E M; Bulat, S A; Gilichinskiĭ, D A

2014-01-01

Archaeal communities of permafrost deposits of King George Island and Bunger Hills Oasis (Antarctica) differing in the content of biogenic methane were analyzed using clone libraries of two 16S rRNA gene regions. Phylotypes belonging to methanogenic archaea were identified in all horizons.

"This immense expense of art": George Eliot and John Ruskin on consumption and the limits of sympathy.

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Coit, Emily

2010-01-01

This essay attempts to better our understanding of George Eliot's conservatism by examining a body of ideas about consumption and moral obligation that she and John Ruskin share. I use a discussion of consumer ethics to explore the moral logic of their conservatism by examining the role of the aesthetic within it. Economic consumption and the aesthetic are subjects inextricably connected, not just because the discourses of political economy and aesthetics have a shared origin in eighteenth-century moral philosophy, but also because the discourse of aesthetics has long served to legitimize select modes and acts of consumption. By marking out a limit where one may reasonably cease to sympathize and instead devote energy (and money) to personal gratification, the treatment of consumption in George Eliot's Middlemarch (1871) offers an important articulation of moral thought. Eliot suggests that aesthetic pleasure can make consumption morally defensible, but she also anticipates Pierre Bourdieu's critique of the aesthetic: her novel represents both the display of cultural capital and the exercise of the aesthetic disposition as ways of maintaining social and economic hierarchies. She thus at once critiques and participates in the system within which the aesthetic functions to preserve social and political stasis. Using John Ruskin's economic writings to expose Middlemarch as a novel of consumer ethics, this essay examines Eliot's representation of personal economic consumption as an emergent mode of social and political agency that might operate productively within that stasis.

Big George to Carter Mountain 115-kV transmission line project, Park and Hot Springs Counties, Wyoming. Environmental Assessment

Energy Technology Data Exchange (ETDEWEB)

1994-02-01

The Western Area Power Administration (Western) is proposing to rebuild, operate, and maintain a 115-kilovolt (kV) transmission line between the Big George and Carter Mountain Substations in northwest Wyoming (Park and Hot Springs Counties). This environmental assessment (EA) was prepared in compliance with the National Environmental Policy Act (NEPA) and the regulations of the Council on Environmental Quality (CEQ) and the Department of Energy (DOE). The existing Big George to Carter Mountain 69-kV transmission line was constructed in 1941 by the US Department of Interior, Bureau of Reclamation, with 1/0 copper conductor on wood-pole H-frame structures without an overhead ground wire. The line should be replaced because of the deteriorated condition of the wood-pole H-frame structures. Because the line lacks an overhead ground wire, it is subject to numerous outages caused by lightning. The line will be 54 years old in 1995, which is the target date for line replacement. The normal service life of a wood-pole line is 45 years. Under the No Action Alternative, no new transmission lines would be built in the project area. The existing 69-kV transmission line would continue to operate with routine maintenance, with no provisions made for replacement.

Twisting and Writhing with George Ellery Hale

Science.gov (United States)

Canfield, Richard C.

2013-06-01

Early in his productive career in astronomy, George Ellery Hale developed innovative solar instrumentation that allowed him to make narrow-band images. Among the solar phenomena he discovered were sunspot vortices, which he attributed to storms akin to cyclones in our own atmosphere. Using the concept of magnetic helicity, physicists and mathematicians describe the topology of magnetic fields, including twisting and writhing. Our contemporary understanding of Hale's vortices as a consequence of large-scale twist in sunspot magnetic fields hinges on a key property of helicity: conservation. I will describe the critical role that this property plays, when applied to twist and writhe, in a fundamental aspect of global solar magnetism: the hemispheric and solar cycle dependences of active region electric currents with respect to magnetic fields. With the advent of unbroken sequences of high-resolution magnetic images, such as those presently available from the Helioseismic and Magnetic Imager on Solar Dynamics Observatory, the flux of magnetic helicity through the photosphere can be observed quantitatively. As magnetic flux tubes buoy up through the convection zone, buffeted and shredded by turbulence, they break up into fragments by repeated random bifurcation. We track these rising flux fragments in the photosphere, and calculate the flux of energy and magnetic helicity there. Using a quantitative model of coronal currents, we also track connections between these fragments to calculate the energy and magnetic helicity stored at topological interfaces that are in some ways analogous to the storage of stress at faults in the Earth's crust. Comparison of these values to solar flares and interplanetary coronal mass ejections implies that this is the primary storage mechanism for energy and magnetic helicity released in those phenomena, and suggests a useful tool for quantitative prediction of geomagnetic storms.

DGCR6 at the proximal part of the DiGeorge critical region is involved in conotruncal heart defects

Science.gov (United States)

Gao, Wenming; Higaki, Takashi; Eguchi-Ishimae, Minenori; Iwabuki, Hidehiko; Wu, Zhouying; Yamamoto, Eiichi; Takata, Hidemi; Ohta, Masaaki; Imoto, Issei; Ishii, Eiichi; Eguchi, Mariko

2015-01-01

Cardiac anomaly is one of the hallmarks of DiGeorge syndrome (DGS), observed in approximately 80% of patients. It often shows a characteristic morphology, termed as conotruncal heart defects. In many cases showing only the conotruncal heart defect, deletion of 22q11.2 region cannot be detected by fluorescence in situ hybridization (FISH), which is used to detect deletion in DGS. We investigated the presence of genomic aberrations in six patients with congenital conotruncal heart defects, who show no deletion at 22q11.2 in an initial screening by FISH. In these patients, no abnormalities were identified in the coding region of the TBX1 gene, one of the key genes responsible for the phenotype of DGS. However, when copy number alteration was analyzed by high-resolution array analysis, a small deletion or duplication in the proximal end of DiGeorge critical region was detected in two patients. The affected region contains the DGCR6 and PRODH genes. DGCR6 has been reported to affect the expression of the TBX1 gene. Our results suggest that altered dosage of gene(s) other than TBX1, possibly DGCR6, may also be responsible for the development of conotruncal heart defects observed in patients with DGS and, in particular, in those with stand-alone conotruncal heart defects. PMID:27081520

A Real-Time Implementable NMPC Output Feedback for a Diesel Engine Air Path Commande prédictive non linéaire avec retour de sortie implémentable en temps-réel pour un circuit d’air d’un moteur Diesel

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Murilo A.

2011-09-01

Full Text Available In this paper, an experimental validation of a parameterized Nonlinear Model Predictive Control (NMPC scheme with a Moving Horizon Observer (MHO is presented for a Diesel engine air path. The control design based on the parameterized approach leads to a low dimensional optimization problem which makes the proposed controller real-time implementable. An attractive feature of this control strategy lies in its compatibility with more elaborated and fully nonlinear models since it uses the model as a black box predictor. Dans cet article, une validation expérimentale d’un schéma de commande prédictive non linéaire (CPNL paramétrique avec un observateur à horizon glissant a été proposé pour le circuit d’air d’un moteur Diesel. La stratégie de commande basée sur l’approche paramétrique à faible dimension s’est montrée implémentable en temps réel et peut être utilisée aussi en tant qu’une solution du type boîte noire indépendamment de la structure du modèle non linéaire.

Between normal and pathological: Ludwik Fleck, Georges Canguilhem and the genesis of historical epistemology

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Mauro Lucio Leitão Condé

2016-05-01

Full Text Available The main purpose of this article is to address, starting from some aspects of the thought of Ludwik Fleck and Georges Canguilhem, the genesis of historical epistemology in the history of science. Specifically, it seeks the contribution of the biological matrix, or the life sciences, presented by these authors, as a central framework in the constitution of historical epistemology. In other words, more than a search of similarities between Fleck and Canguilhem, the main goal is to show how, in formulating independently their ideas of history of science – especially the history of medicine – these authors contributed decisively to the basis of a historical epistemology that will be, throughout the twentieth century, a new thought style for understanding the history of science.

Uma educação pela natureza: o método de educação física de Georges Hébert

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Carmen Lúcia Soares

2015-06-01

Full Text Available Diferentes concepções de natureza são inventadas pela ordem urbana no início do século XX. Fabrica-se um ideário médico-pedagógico de valorização da vida ao ar livre e de práticas educativas junto à natureza. Afirma-se naquele momento um naturismo pedagógico que não tardará a prescrever uma prática regular de jogos e de exercícios físicos ao ar livre em diferentes espaços, inclusive na instituição escolar. Para analisar esse ideário, este artigo trata de alguns aspectos da obra de Georges Hébert, cujas ideias centrais evocam um retorno à natureza a partir de distintas práticas educativas feitas ao ar livre. Como fontes primárias usamos parte da obra de Georges Hébert produzida entre 1905 e 1936.

Claiming mastery of the word : The power of discourse in Ray Bradbury's Fahrenheit 451 and George Orwell's 1984

OpenAIRE

Wien, Henriette

2012-01-01

In this thesis, the main objective is to look at the power of discourse in relation to two dystopian texts, George Orwell’s Nineteen Eighty-Four (1948) and Ray Bradbury’s Fahrenheit 451 (1953). Additionally, the thesis proposes how these two texts, as well as literary texts in general, are suitable for the teaching of English as a foreign language (TEFL) in upper secondary school, especially in terms of a pupil’s personal development. Since a majority of dystopian literary texts are concerned...

O humano e o desumano: cultura visual, cultura política e as imagens feitas por George Rodger e Henri Cartier-Bresson nos campos de concentração nazistas

OpenAIRE

Erika Cazzonatto Zerwes

2016-01-01

Este artigo busca compreender alguns aspectos da noção de humanismo na fotografia e sua proximidade com a cultura política e a cultura visual do período, a partir das experiências específicas de George Rodger e Henri Cartier-Bresson, dois fotógrafos que viveram em primeira mão e que deram testemunho do horror dos campos de concentração nazistas ao final da Segunda Guerra Mundial. George Rodger fotografou o campo de Bergen-Belsen assim que foi libertado pelas tropas britânicas. Henri Cartier-B...

Georges Marinesco (1863-1938): neurologist, neurohistologist and neuropathologist.

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Catala, M; Poirier, J

2012-01-01

Gheorghe Marinescu (Georges Marinesco, in French) is a Romanian physician, founder of the School of Neurology in that country. He begins his medical studies in Bucharest, then has the opportunity to reach Paris and join the School of Neurology in La Salpêtrière Hospital, lead by Jean-Martin Charcot. This trip will forever imprint the mind of Marinescu, a great friend of France, a respectful student of Charcot and a friendly colleague of many Parisian neurologists. Marinescu's works are multiple and very important. He describes the succulent hand in syringomyelia and the palmar-jaw reflex. Marinescu is also one of the first to use the cinema for medical purposes. His work as an anatomo-clinician, a method developed by Charcot, is important. We denote the description of the locus niger affected by tuberculosis in a case of parkinsonism (this description paving Etienne Brissaud's way to highlight the anatomical origin of Parkinson's disease), the original clinical description of Marinesco-Sjögren syndrome, and that of medullomyoblastoma. Marinescu is also a famous neurocytologist as evidenced by his work, La Cellule Nerveuse, published in 1909. The first volume of the book is devoted to the aspects of the normal nervous tissue: the neurofibrillar network, the chromatophilic elements, and the paranucleolar corpuscles (now known as Marinescu's bodies). The second volume of the book is almost related to features revealed by experimental lesions: chromatolysis and neuronophagia. Furthermore, Marinescu describes with Oscar Blocq, small nodules than are now regarded as the first description of senile plaques.

PRILAKU SEKS BEBAS REMAJA DI KABUPATEN PONOROGO PERSEPKETIF INTERAKSIONALISME SIMBOLIK GEORGE HERBERT MEAD

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M. Harir Muzakki

2010-12-01

Full Text Available Abstraks: Penelitian ini berusaha mengungkap proses terjadinya prilaku seks bebas di kalangan remaja dalam interaksionalisme simbolik George Herbert Mead dan pola interaksi seks bebas di kalangan remaja di kabupaten Ponorogo. Penelitian ini bersifat deskriptif-analitis dan didesain dengan pendekatan kualitatif. Data diambil dengan cara wawancara dengan para pelaku sek bebas. Ada beberapa tahapan sebelum aktor melakukan tindakan atau hubungan seks yaitu, impuls, persepsi,manipulasi dan terakhir konsumasi. Dari hasil penilitian dapat disimpulkan bahwa proses terjadinya seks bebas pada awalnya mereka tertarik dengan lawan jenisnya. Kemudian melakukan pendekatan, saling melirik, berkenalan, kemudian pacaran. Tahap berikutnya mereka saling berpegangan, berciuman, meremas payudara, kedudian melakukan hubungan seks. Sementara pola interaksi seks bebas di kalangan remaja ada dua: pertama, remaja melakukan hubungan seks bebas dengan pacarnya sendiri. Kedua, remaja tersebut melakukan hubungan dengan membeli atau menyewa wanita lain.

Translation to Spanish and Validation of the Specific Saint George's Questionnaire for Idiopathic Pulmonary Fibrosis.

Science.gov (United States)

Capparelli, Ignacio; Fernandez, Martín; Saadia Otero, Marcela; Steimberg, Jimena; Brassesco, María; Campobasso, Ana; Palacios, Sandra; Caro, Fabian; Alberti, María Laura; Rabinovich, Roberto A; Paulin, Francisco

2018-02-01

Interstitial lung disease (ILD) is associated with low exercise tolerance, dyspnea, and decreased health-related quality of life (HRQL). Idiopathic pulmonary fibrosis (IPF) is one of the most prevalent in the group. A specific version of the Saint George's questionnaire (SGRQ-I) has been developed to quantify the HRQL of IPF patients. However, this tool is not currently validated in the Spanish language. The objective was to translate into Spanish and validate the specific Saint George's Respiratory Questionnaire for idiopathic pulmonary fibrosis (SGRQ-I). The repeatability, internal consistency and construct validity of the SGRQ-I in Spanish were analyzed after a backtranslation process. In total, 23 outpatients with IPF completed the translated SGRQ-I twice, 7 days apart. Repeatability was studied, revealing good concordance in test-retest with an ICC (interclass correlation coefficient) of 0.96 (P<.001). Internal consistency was good for different questionnaire items (Cronbach's alpha of 0.9 including and 0.81 excluding the total value) (P<.001). The total score of the questionnaire showed good correlation with forced vital capacity FVC% (r=-0.44; P=.033), diffusing capacity of the lungs for carbon monoxide (DL CO %) (r=-0.55; P=.011), partial pressure of oxygen in arterial blood PaO 2 (r=-0.44; P=.036), Medical Research Council Dyspnea scale (r=-0.65; P<.001), and number of steps taken in 24hours (r=-0.47; P=.024). The Spanish version of SGRQ-Ideveloped by our group shows good internal consistency, reproducibility and validity, so it can be used for the evaluation of quality of life (QOL) in IPF patients. Copyright © 2017 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.

Holocene sea-level changes in King George Island, West Antarctica, by virtue of geomorphological coastal evidences and diatom assemblages of sediment sections.

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Poleshchuk, Ksenia; Verkulich, Sergey; Pushina, Zina; Jozhikov, Ilya

2015-04-01

A new curve of relative sea-level change is presented for the Fildes peninsula, King George Island, West Antarctic. This work is based on renewed paleogeography data, including coastal geomorphological evidence, diatom assemblages of lakes bottom sediments and radiocarbon datings of organics. The new data were obtained in several sections of quaternary sediments and groups of terraces, and allows us to expand and improve relevant conception about relative sea level changes in the King George Island region. The new radiocarbon datings of organics (mosses and shells) allows reconstructing Holocene conditions that maintain and cause the sea-level changes. Sea diatom assemblages of Dlinnoye lake bottom sediment core (that complies period about 8000 years B.P.) mark altitude of marine water penetrated into the lake. The altitudes of shell remains, which have certain life habits and expect specific salinity and depth conditions, coupled with their absolute datings, indicate the probable elevation of the past sea level. The Mid-Holocene marine transgression reached its maximum level of 18-20 m by 5760 years B.P. The transgression influenced the deglaciation of the Fildes peninsula and environment conditions integrally. The ratio of glacio-isostatic adjustment velocity and Holocene transgression leaded to the decrease of relative sea level during the Late Holocene excluding the short period of rising between 2000 and 1300 years B.P. Comparing this data with the curve for Bunger oasis, East Antarctica, introduced earlier gives an interesting result. Despite the maximum altitudes of relative sea-level rise in King George region were higher and occurred later than in Bunger oasis region, the short-term period of Late Holocene sea-level rising contemporizes. Besides that, this work allow to realize a correlation between regions of Antarctica and adjacent territory. That, in turn, lets answer the question of tectonic and eustatic factors ratio and their contribution to the

78 FR 39964 - Amendment of Restricted Areas R-2907A and R-2907B, Lake George, FL; and R-2910, Pinecastle, FL

Science.gov (United States)

2013-07-03

...-1146; Airspace Docket No. 10-ASO-25] RIN 2120-AA66 Amendment of Restricted Areas R-2907A and R-2907B, Lake George, FL; and R-2910, Pinecastle, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... commenters objected to the proposed establishment of two new restricted areas, R-2907B (located between R...

George Beard and Lydia Pinkham: gender, class, and nerves in late 19th century America.

Science.gov (United States)

Davis, D L

1989-01-01

A historical comparison of the careers of George Beard, medical doctor, and Lydia Pinkham, feminist and patent medicine maker, demonstrates the complex social nature of the experience of nerves among late 19th century women. Special attention is paid to the roles played by changing gender and class ideologies in Pinkham's and Beard's theories of nerves during the period from the 1870s to World War I. A comparison of contemporary anthropological and historical studies of gender and nerves leads to the conclusion that nerves, as a female complaint, takes hold of the popular and medical imagination during periods of dramatic social change which threaten women's traditional family roles and challenge their sense of self-identity.

La filosofia di Hans-Georg Gadamer e il problema del disagio della modernità. Ermeneutica, estetica, etica e politica

OpenAIRE

Marino, Stefano

2008-01-01

L’ermeneutica filosofica di Hans-Georg Gadamer – indubbiamente uno dei capisaldi del pensiero novecentesco – rappresenta una filosofia molto composita, sfaccettata e articolata, per così dire formata da una molteplicità di dimensioni diverse che si intrecciano l’una con l’altra. Ciò risulta evidente già da un semplice sguardo alla composizione interna della sua opera principale, Wahrheit und Methode (1960), nella quale si presenta una teoria del comprendere che prende in esame ...

Nonlinear EGR and VGT Control with Integral Action for Diesel Engines Régulation de Recirculation des Gaz d’Echappement (RGE et de Turbine à Géométrie Variable (TGV non linéaire avec action intégrée pour moteurs Diesel

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Wahlström J.

2011-10-01

Full Text Available A nonlinear multivariable control design with integral action is proposed and investigated for control of Exhaust Gas Recirculation (EGR and Variable Geometry Turbine (VGT in heavy duty Diesel engines. The main control goal is to regulate oxygen/fuel ratio and intake manifold EGR-fraction, and they are specified in an outer loop. These are chosen as main performance variables since they are strongly coupled to the emissions. An existing nonlinear control design based on feedback linearization is extended with integral action. In particular, the control design method utilizes a control Lyapunov function, inverse optimal control, and a nonlinear input transformation. Comparisons between different control structures are performed in simulations showing the following four points. Firstly, integral action is necessary to handle model errors so that the controller can track the performance variables specified in the outer loop. Secondly, the proposed control design handles the nonlinear effects in the Diesel engine that results in less control errors compared to a control structure with PID controllers. Thirdly, it is important to use the input transformation and it is sufficient to use a control structure with PID controllers and input transformation to handle the nonlinear effects. Fourthly, the proposed control design is sensitive to model errors in the input transformation while a control structure with PID controllers and input transformation handles these model errors. Une conception de régulation non linéaire à variables multiples avec action intégrée est proposée et étudiée pour une régulation de la Recirculation des Gaz d’Echappement (RGE et une Turbine à Géométrie Variable (TGV au sein de moteurs Diesel à usage industriel. L’objectif principal de la régulation consiste à réguler le rapport oxygène / carburant et la fraction de RGE de tubulure d’admission, qui sont spécifiés au sein d’une boucle extérieure. Ceux

Mesoporous Silica-Supported Metal Oxide-Promoted Rh Nanocatalyst for Selective Production of Ethanol from Syngas

Energy Technology Data Exchange (ETDEWEB)

Kraus, George

2010-09-30

The objective is to develop a process that will convert synthesis gas from coal into ethanol and then transform the ethanol into hydrogen. Principal investigators from Iowa State University include Dr. George Kraus, Dr. Victor Lin, Marek Pruski, and Dr. Robert Brown. Task 1 involves catalyst development and catalyst scale up. Mesoporous manganese silicate mixed oxide materials will be synthesized, characterized and evaluated. The first-and secondgeneration catalysts have been prepared and scaled up for use in Task 2. The construction of a high-pressure reactor system for producing synthetic liquid fuel from simulated synthesis gas stream has been completed as the first step in Task 2. Using the first- and second generation catalysts, the reactor has demonstrated the production of synthetic liquid fuel from a simulated synthesis gas stream.

The Death of Georges Seurat: Neo-Impressionism and the Fate of the Avant-Garde in 1891

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Young, Marnin

2012-07-01

Full Text Available This essay examines the critical and artistic responses to the death of Georges Seurat in 1891. While some at the time saw the avant-garde divided between scientifically-oriented neo-impressionism and mystical symbolism, the posthumous understanding of Seurat's work increasingly collapsed the two categories. In particular, the neo-impressionist embrace of the aesthetic of Charles Henry, in which compositional lines produced predictable effects on the viewer, made it possible to see Seurat's paintings in purely formal, indeed idealist, terms. The neo-impressionist avant-garde consequently struggled to define its distinctive nature over the course of the year, with important consequences for later art.