WorldWideScience

Sample records for liang wei-shuo fang

  1. San luo xuan mo xing ji qi liang hua fen zhi fang fa yan tao

    NARCIS (Netherlands)

    Ye, Y.; Leydesdorff, L.; Wu, Y.

    2014-01-01

    A discussed study on the Triple Helix with its quantitative analysis method. With brief introduction to background and progress of Triple-Helix(TH) researches, it is clarified that TH quantitative methodology focuses on the indicator of synergy (T) as reduction of uncertainty that can be shaped

  2. Fang Dongmeijeva filozofija ustvarjalnega kozmosa

    Directory of Open Access Journals (Sweden)

    Jana S. ROŠKER

    2014-12-01

    Full Text Available Fang Dongmei (1899–1977 is one of the main representatives of the second generation of Modern Confucianism, though he never explicitly claimed to be only a Confucian, but stressed being––in his soul––also a Daoist and Buddhist. The theoretical contribution of this philosopher (who is still rather neglected in the West to the development of modern Chinese philosophy is doubtlessly worth detailed research. The present article mainly deals with the analysis and interpretation of the ontological and epistemological aspects of his philosophy. It focuses upon the introduction of the following concepts, central to his philosophy: comprehensive harmony, Confucian moral self, creative creativity, unity of facts and values, as well as reason and intuition.

  3. [Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

    Science.gov (United States)

    Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

    2014-01-01

    Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

  4. More on the Liang Bua finds and modern human cretins.

    Science.gov (United States)

    Oxnard, Charles; Obendorf, Peter J; Kefford, Ben J; Dennison, John

    2012-12-01

    Brown (2012: LB1 and LB6 Homo floresiensis are not modern human (Homo sapiens) cretins, Journal of Human Evolution) makes errors of fact, omission and interpretation. Brown's comments refer, among others, to (1) delayed growth and development indicated by unfused epiphyses, (2) postcranial limb proportions: limbs to trunk, between limbs, and within limbs, (3) postcranial bone torsions and angles, (4) postcranial robusticity, real and apparent, (5) skull features, and (6) cretinism on Flores. In each of these areas, much information about cretins is incorrect and much information (Oxnard et al., 2010) comparing the Liang Bua remains with cretins is ignored. Copyright © 2012 Elsevier GmbH. All rights reserved.

  5. The effect of 'Liang-Feng-Su' on increasing production of sweet potato

    International Nuclear Information System (INIS)

    Liu Yitong; Wang Zhifen

    1991-01-01

    Treating sweet potato seedling with 33 x 10 -6 'Liang-Feng-Su', by means of phosphorus-32 and carbon-14 tracing technique showed that the use of 'Liang-Feng-Su' not only increased the root vigor and net photosynthetic efficiency of leaves, but also promoted the transport of photosynthate to root tubers which results in economic benefit

  6. Liu Fang Yuan at The Huntington——An Overview

    Institute of Scientific and Technical Information of China (English)

    (USA)Laurie Sowd

    2009-01-01

    Liu Fang Yuan is a classical Chinese Garden, the Garden of Flowing Fragrance, a most remarkable project in Huntington. This project was conceived by James Folsom. It is an international business venture, complex construction project, unique China-US collaboration, and center of cultural memory. Inspired by the centuries-old Chinese tradition of private gardens, Liu Fang Yuan combines the scenic beauty of nature with the expressiveness of literature to give deeper meaning to the landscape. True to the authentic nature of a Chinese garden, the design respects the site. It extends to adapting some of the traditional elements of Chinese garden design to meet local needs for seismic safety and wheelchair accessibility. Liu Fang Yuan is the only truly seasonal garden at the Huntington, emphasizing and symbolizing the progression of winter, spring, summer, and autumn. The visitor experiences more than the visual realm. The garden's name, Liu Fang Yuan, has bolh literal and symbolic meanings refer to the scent of flowers and trees, also echoes the name of famed Ming dynasty painter Li Liufang. Liu Fang Yuan is truly a microcosm of The Huntington, bringing together botany, art and literature in a garden that will serve as a place of cultural memory and center for education about one of the great humanities traditions of the world.

  7. Effect of Songyu Anshen Fang on expression of hypothalamic GABA ...

    African Journals Online (AJOL)

    Purpose: To investigate the effects of the Chinese compound, Songyu Anshen Fang (SYF) on levels of GABA and GABA(B) receptor proteins in insomniac rats induced by para-chlorophenylalanine (PCPA). Methods: All rats were randomly separated into either a control group, insomnia group, or a SYF group (at a dose of ...

  8. Physiological traits contributing to carbon storage variation in Monastery bamboo and Pai Liang in northeastern Thailand

    Directory of Open Access Journals (Sweden)

    Nisa Leksungnoen

    2017-04-01

    Full Text Available This study aims at comparing the carbon storage ability of Monastery bamboo (Thyrsostachys siamensis Gamble and Pai Liang (Dendrocalamus membranaceus × Thyrsostachys siamensis in terms of the different physiological responses to the microclimate. The stomatal conductance, leaf-to-air vapor pressure deficit (LAVPD, chlorophyll content, and water use efficiency (WUE were measured. Pai Liang had a greater dry biomass per culm than Monastery bamboo, resulting in more carbon storage. Monastery bamboo kept opening its stomata even when LAVPD increased, resulting in the loss of more water and a lower WUE leading to a lower rate of growth and carbon storage. Pai Liang contained higher amount of carbon and nitrogen in the leaf tissue, indicating a better WUE. With regards to the climate change, Pai Liang is recommended owing to a greater carbon fixation and more rapid growth rate compared to the Monastery bamboo.

  9. Pygmoid Australomelanesian Homo sapiens skeletal remains from Liang Bua, Flores: Population affinities and pathological abnormalities

    OpenAIRE

    Jacob, T.; Indriati, E.; Soejono, R. P.; Hsü, K.; Frayer, D. W.; Eckhardt, R. B.; Kuperavage, A. J.; Thorne, A.; Henneberg, M.

    2006-01-01

    Liang Bua 1 (LB1) exhibits marked craniofacial and postcranial asymmetries and other indicators of abnormal growth and development. Anomalies aside, 140 cranial features place LB1 within modern human ranges of variation, resembling Australomelanesian populations. Mandibular and dental features of LB1 and LB6/1 either show no substantial deviation from modern Homo sapiens or share features (receding chins and rotated premolars) with Rampasasa pygmies now living near Liang Bua Cave. We propose ...

  10. Viperous fangs: development and evolution of the venom canal.

    Science.gov (United States)

    Zahradnicek, Oldrich; Horacek, Ivan; Tucker, Abigail S

    2008-01-01

    Fangs are specialised long teeth that contain either a superficial groove (Gila monster, Beaded lizard, some colubrid snakes), along which the venom runs, or an enclosed canal (viperid, elapid and atractaspid), down which the venom flows inside the tooth. The fangs of viperid snakes are the most effective venom-delivery structures among vertebrates and have been the focus of scientific interests for more than 200 years. Despite this interest the questions of how the canal at the centre of the fang forms remains unresolved. Two different hypotheses have been suggested. The mainstream hypothesis claims that the venom-conducting canal develops by the invagination of the epithelial wall of the developing tooth germ. The sides of this invagination make contact and finally fuse to form the enclosed canal. The second hypothesis, known as the "brick chimney", claims the venom-conducting canal develops directly by successive dentine deposition as the tooth develops. The fang is thus built up from the tip to the base, without any folding of the tooth surface. In an attempt to cast further light on this subject the early development of the fangs was followed in a pit viper, Trimeresurus albolabris, using the expression of Sonic hedgehog (Shh). We demonstrate that the canal is indeed formed by an early folding event, resulting from an invagination of epithelial cells into the dental mesenchyme. The epithelial cells proliferate to enlarge the canal and then the cells die by apoptosis, forming an empty tube through which the poison runs. The entrance and discharge orifices at either end of the canal develop by a similar invagination but the initial width of the invagination is very different from that in the middle of the tooth, and is associated with higher proliferation. The two sides of the invaginating epithelium never come into contact, leaving the orifice open. The mechanism by which the orifices form can be likened to that observed in reptiles with an open groove along

  11. The viper fangs: clinical anatomy, principles of physical examination and therapy (a review

    Directory of Open Access Journals (Sweden)

    Matteo Oliveri

    2016-01-01

    Full Text Available The assessment of fangs is a fundamental part of clinical examination of viperid snakes. The long curved venom fang is carried by short, highly mobile maxilla. Short anaesthesia is advised for safe physical examination and radiography of the mouth cavity. The fangs are gently forced outside the fang pocket by passing the bar or forceps on the palato-maxillary arch, and rotating them rostrally shifting the mucosal fold. Functional fangs are periodically shed and several generations of replacement teeth lie behind and beneath each fang. In case of fang fracture, therapy should be limited to flushing with a solution of chlorhexidine or povidone iodine, and topical application of pro-coagulant and antibacterial cream. Therapy of chronic fang inflammation is based on removal of necrotized fang and repeated abundant irrigation of the fang pocket. Treatment of chronic stomatitis consists of flushing with chlorhexidine or povidone iodine, physical removal of the plaques, administration of analgesics and antibiotics (marbofloxacin, enrofloxacin or ceftazidime. Extra-oral surgical approach is the best method for odontogenic abscess removal. A vigorous flushing with sterile saline solution, chlorhexidine and povidone iodine and topical application of antibiotics (antibiotic embedded surgical sponge is advised. Force feeding of the anorectic patient suffering from fang inflammation is a mandatory part of the standard treatment protocol.

  12. PENGEMASAN PAKET EKOWISATA DI DESA LIANG NDARA, KECAMATAN MBELILING, KABUPATEN MANGGARAI BARAT, FLORES, NUSA TENGGARA TIMUR

    Directory of Open Access Journals (Sweden)

    Charles Bertomi

    2015-12-01

    Full Text Available Liang Ndara village is one of the village in Mbeliling sub-district, West Manggarai regency, Flores of East Nusa Tenggara Province. Liang Ndara village has many tourism potentials specifically regarding to the ecotourism. Free entrance fee in to those tourism places caused by unserious and less attention of the government are becoming problem, as well as Lack of human resources of people is another problem causing the potentials are not well organized yet and even it is not in a good tourism packaging. The research aim to find out the tourism potential that can be made ecotourism packages and packaging them to become an ecotourism in Liang Ndara village. The data collection of this research is by an observation, documentation, interviewing and as well as literature. The data analysis technic used is by analysis technic of qualitative descriptive. The results of this research showed that Liang Ndara village has three kinds of tourism potential which is in a packaging of ecotourism. Those potentials are the natural tourism potentials consist of Mbeliling Mountain, Cunca rami waterfall, Cunca Wae Kantor waterfall and Liang Niki Cave. The cultural tourism potentials are Caci dance, Compang Kafir Stone, Compang Serani statue, Batu Tiga, Hand Weaving of Songke, Farming Activities such as sopi/arak filtration, cultivating of rice field. Man made tourism potentials are information center in the village, guest house, and souvenir shops. The potentials above are packaged in to two kind of ecotourism packages they are Liang Ndara Village Tour and Mbeliling Green Forest Tour. The suggestions are the government is supposed to put their eyes on to develop those potential exist and need to be hand in hand with the tourism actors as well as the society. The travel agencies are expected to make an interesting tourism package like ecotourism and also supposed to be together with the society to take care and survive the tourism potentials existed.

  13. Pygmoid Australomelanesian Homo sapiens skeletal remains from Liang Bua, Flores: population affinities and pathological abnormalities.

    Science.gov (United States)

    Jacob, T; Indriati, E; Soejono, R P; Hsü, K; Frayer, D W; Eckhardt, R B; Kuperavage, A J; Thorne, A; Henneberg, M

    2006-09-05

    Liang Bua 1 (LB1) exhibits marked craniofacial and postcranial asymmetries and other indicators of abnormal growth and development. Anomalies aside, 140 cranial features place LB1 within modern human ranges of variation, resembling Australomelanesian populations. Mandibular and dental features of LB1 and LB6/1 either show no substantial deviation from modern Homo sapiens or share features (receding chins and rotated premolars) with Rampasasa pygmies now living near Liang Bua Cave. We propose that LB1 is drawn from an earlier pygmy H. sapiens population but individually shows signs of a developmental abnormality, including microcephaly. Additional mandibular and postcranial remains from the site share small body size but not microcephaly.

  14. Has snake fang evolution lost its bite? New insights from a structural mechanics viewpoint.

    Science.gov (United States)

    Broeckhoven, Chris; du Plessis, Anton

    2017-08-01

    Venomous snakes-the pinnacle of snake evolution-are characterized by their possession of venom-conducting fangs ranging from grooved phenotypes characterizing multiple lineages of rear-fanged taxa to tubular phenotypes present in elapids, viperids and atractaspidines. Despite extensive research, controversy still exists on the selective pressures involved in fang phenotype diversification. Here, we test the hypothesis that larger fangs and consequently a shift to an anterior position in the maxilla evolved to compensate for the costs of structural changes, i.e. higher stress upon impact in tubular fangs compared to grooved fangs. Direct voxel-based stress simulations conducted on high-resolution µCT scans, analysed within a phylogenetic framework, showed no differences in stress distribution between the three fang phenotypes, despite differences in (relative) fang length. These findings suggest that additional compensatory mechanisms are responsible for the biomechanical optimization and that fang length might instead be related to differential striking behaviour strategies. © 2017 The Author(s).

  15. Revised stratigraphy and chronology for Homo floresiensis at Liang Bua in Indonesia

    DEFF Research Database (Denmark)

    Sutikna, Thomas; Tocheri, Matthew W.; Morwood, Michael J.

    2016-01-01

    Homo floresiensis, a primitive hominin species discovered in Late Pleistocene sediments at Liang Bua (Flores, Indonesia), has generated wide interest and scientific debate. A major reason this taxon is controversial is because the H. floresiensis-bearing deposits, which include associated stone...

  16. Bottom of the Iceberg: The Archontic Text - Review of Fanged Fan Fiction (McFarland, 2013)

    DEFF Research Database (Denmark)

    Schubart, Rikke

    2014-01-01

    Anmeldelse af Lindgren, Maria og Malin Isaksson, Fanged Fan Fiction: Variations on Twilight, True Blood and The Vampire Diaries (McFarland, 2013)......Anmeldelse af Lindgren, Maria og Malin Isaksson, Fanged Fan Fiction: Variations on Twilight, True Blood and The Vampire Diaries (McFarland, 2013)...

  17. Psychoanalysis of Jack London's "The Call of the Wild" and "White Fang"

    Science.gov (United States)

    Yang, Hongyan

    2015-01-01

    "The Call of the Wild" and "White Fang" both are masterpieces of Jack London. The protagonists Buck and White Fang are the incarnation of Jack himself to some extent for the two novels reveal a great deal of the writer. This essay aims at psychoanalyzing Jack London's creative process, the Oedipus complex and the confliction…

  18. [Needling technique of Professor Li Yan-Fang].

    Science.gov (United States)

    Li, Li-Jun

    2014-01-01

    Experiences of needling techniques of Professor LI Ya- fang is introduced in this article. Gentle and superficial insertion is adopted by Professor LI in clinic. Emphases are put on the qi regulation function, needling sensation to the affected region and insertion with both hands, especially the function of the left hand as pressing hand. The gentle and superficial insertion should be done as the follows: hold the needle with the right hand, press gently along the running course of meridians with the left hand to promote qi circulation, hard pressing should be applied at acupoints to disperse the local qi and blood, insert the needle gently and quickly into the subcutaneous region with the right hand, and stop the insertion when patient has the needling sensation. While the fast needling is characterized with shallow insertion and swift manipulation: the left hand of the manipulator should press first along the running course of the meridian, and fix the local skin, hold the needle with the right hand and insert the needle quickly into the acupoint. Withdrawal of the needle should be done immediately after the reinforcing and reducing manipulations. Professor LI is accomplished in qi regulation. It is held by him that regulating qi circulation is essence of acupuncture, letting the patient get the needling sensation is the most important task of needling. Lifting, thrusting and rotation manipulations should be applied to do reinforcing or reducing. The tissue around the tip of the needle should not be too contracted or too relaxed, and the resistance should not be too strong or too weak. The feeling of the insertion hand of the practitioner should not be too smooth or too hesitant. Needle should be inserted into the skin quickly at the moment of hard pressing by the left hand. And then, slow rotation and gentle lifting and thrusting can be applied to promote the needling sensation like electric current pass through and to reach the affected region along the

  19. Late Pleistocene songbirds of Liang Bua (Flores, Indonesia); the first fossil passerine fauna described from Wallacea

    Science.gov (United States)

    Sutikna, Thomas; Saptomo, Wahyu; Jatmiko; Wasisto, Sri; Tocheri, Matthew W.; Mayr, Gerald

    2017-01-01

    Background Passerines (Aves: Passeriformes) dominate modern terrestrial bird communities yet their fossil record is limited. Liang Bua is a large cave on the Indonesian island of Flores that preserves Late Pleistocene–Holocene deposits (∼190 ka to present day). Birds are the most diverse faunal group at Liang Bua and are present throughout the stratigraphic sequence. Methods We examined avian remains from the Late Pleistocene deposits of Sector XII, a 2 × 2 m area excavated to about 8.5 m depth. Although postcranial passerine remains are typically challenging to identify, we found several humeral characters particularly useful in discriminating between groups, and identified 89 skeletal elements of passerines. Results At least eight species from eight families are represented, including the Large-billed Crow (Corvus cf. macrorhynchos), the Australasian Bushlark (Mirafra javanica), a friarbird (Philemon sp.), and the Pechora Pipit (Anthus cf. gustavi). Discussion These remains constitute the first sample of fossil passerines described in Wallacea. Two of the taxa no longer occur on Flores today; a large sturnid (cf. Acridotheres) and a grassbird (Megalurus sp.). Palaeoecologically, the songbird assemblage suggests open grassland and tall forests, which is consistent with conditions inferred from the non-passerine fauna at the site. Corvus cf. macrorhynchos, found in the Homo floresiensis-bearing layers, was likely part of a scavenging guild that fed on carcasses of Stegodon florensis insularis alongside vultures (Trigonoceps sp.), giant storks (Leptoptilos robustus), komodo dragons (Varanus komodoensis), and probably H. floresiensis as well. PMID:28828271

  20. Late Pleistocene songbirds of Liang Bua (Flores, Indonesia; the first fossil passerine fauna described from Wallacea

    Directory of Open Access Journals (Sweden)

    Hanneke J.M. Meijer

    2017-08-01

    Full Text Available Background Passerines (Aves: Passeriformes dominate modern terrestrial bird communities yet their fossil record is limited. Liang Bua is a large cave on the Indonesian island of Flores that preserves Late Pleistocene–Holocene deposits (∼190 ka to present day. Birds are the most diverse faunal group at Liang Bua and are present throughout the stratigraphic sequence. Methods We examined avian remains from the Late Pleistocene deposits of Sector XII, a 2 × 2 m area excavated to about 8.5 m depth. Although postcranial passerine remains are typically challenging to identify, we found several humeral characters particularly useful in discriminating between groups, and identified 89 skeletal elements of passerines. Results At least eight species from eight families are represented, including the Large-billed Crow (Corvus cf. macrorhynchos, the Australasian Bushlark (Mirafra javanica, a friarbird (Philemon sp., and the Pechora Pipit (Anthus cf. gustavi. Discussion These remains constitute the first sample of fossil passerines described in Wallacea. Two of the taxa no longer occur on Flores today; a large sturnid (cf. Acridotheres and a grassbird (Megalurus sp.. Palaeoecologically, the songbird assemblage suggests open grassland and tall forests, which is consistent with conditions inferred from the non-passerine fauna at the site. Corvus cf. macrorhynchos, found in the Homo floresiensis-bearing layers, was likely part of a scavenging guild that fed on carcasses of Stegodon florensis insularis alongside vultures (Trigonoceps sp., giant storks (Leptoptilos robustus, komodo dragons (Varanus komodoensis, and probably H. floresiensis as well.

  1. Revised stratigraphy and chronology for Homo floresiensis at Liang Bua in Indonesia.

    Science.gov (United States)

    Sutikna, Thomas; Tocheri, Matthew W; Morwood, Michael J; Saptomo, E Wahyu; Jatmiko; Awe, Rokus Due; Wasisto, Sri; Westaway, Kira E; Aubert, Maxime; Li, Bo; Zhao, Jian-xin; Storey, Michael; Alloway, Brent V; Morley, Mike W; Meijer, Hanneke J M; van den Bergh, Gerrit D; Grün, Rainer; Dosseto, Anthony; Brumm, Adam; Jungers, William L; Roberts, Richard G

    2016-04-21

    Homo floresiensis, a primitive hominin species discovered in Late Pleistocene sediments at Liang Bua (Flores, Indonesia), has generated wide interest and scientific debate. A major reason this taxon is controversial is because the H. floresiensis-bearing deposits, which include associated stone artefacts and remains of other extinct endemic fauna, were dated to between about 95 and 12 thousand calendar years (kyr) ago. These ages suggested that H. floresiensis survived until long after modern humans reached Australia by ~50 kyr ago. Here we report new stratigraphic and chronological evidence from Liang Bua that does not support the ages inferred previously for the H. floresiensis holotype (LB1), ~18 thousand calibrated radiocarbon years before present (kyr cal. BP), or the time of last appearance of this species (about 17 or 13-11 kyr cal. BP). Instead, the skeletal remains of H. floresiensis and the deposits containing them are dated to between about 100 and 60 kyr ago, whereas stone artefacts attributable to this species range from about 190 to 50 kyr in age. Whether H. floresiensis survived after 50 kyr ago--potentially encountering modern humans on Flores or other hominins dispersing through southeast Asia, such as Denisovans--is an open question.

  2. Understanding Biological Roles of Venoms Among the Caenophidia: The Importance of Rear-Fanged Snakes.

    Science.gov (United States)

    Mackessy, Stephen P; Saviola, Anthony J

    2016-11-01

    Snake venoms represent an adaptive trophic response to the challenges confronting a limbless predator for overcoming combative prey, and this chemical means of subduing prey shows several dominant phenotypes. Many front-fanged snakes, particularly vipers, feed on various vertebrate and invertebrate prey species, and some of their venom components (e.g., metalloproteinases, cobratoxin) appear to have been selected for "broad-brush" incapacitation of different prey taxa. Using proteomic and genomic techniques, the compositional diversity of front-fanged snakes is becoming well characterized; however, this is not the case for most rear-fanged colubroid snakes. Because these species consume a high diversity of prey, and because venoms are primarily a trophic adaptation, important clues for understanding specific selective pressures favoring venom component composition will be found among rear-fanged snake venoms. Rear-fanged snakes typically (but not always) produce venoms with lower complexity than front-fanged snakes, and there are even fewer dominant (and, arguably, biologically most relevant) venom protein families. We have demonstrated taxon-specific toxic effects, where lizards and birds show high susceptibility while mammals are largely unaffected, for both Old World and New World rear-fanged snakes, strongly indicating a causal link between toxin evolution and prey preference. New data are presented on myotoxin a, showing that the extremely rapid paralysis induced by this rattlesnake toxin is specific for rodents, and that myotoxin a is ineffectual against lizards. Relatively few rear-fanged snake venoms have been characterized, and basic natural history data are largely lacking, but directed sampling of specialized species indicates that novel compounds are likely among these specialists, particularly among those species feeding on invertebrate prey such as scorpions and centipedes. Because many of the more than 2200 species of colubroid snakes are rear-fanged

  3. [Experience of professor FANG Jianqiao treating trigeminal neuralgia at different stages].

    Science.gov (United States)

    Sun, Jing; Fang, Jianqiao; Shao, Xiaomei; Chen, Lifang

    2016-02-01

    Trigerninal neuralgia is a common refractory disease in clinic. Professor FANG Jianqiao has rich experience through diagnosing and treating the disease for many years. In the first diagnosis, professor FANG underlines the position of damaged neuron and syndrome differentiation. He considers acupuncture should be implemented by stages,namely according to whether the patients are in the period of pain attack, different acupuocture prescriptions are made. Acupuncture manipulation and needle-retention time should be adjusted according to the condition of disease. And the appropriate application of electroacupuncture and transcutaneous electrical acupoint stimulation can strengthen the effect.

  4. Experimental study of desulfurization of Zhong Liang Shau high sulfur coal by flotation

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Z.; Huang, B.; Cao, J. [China University of Mining and Technology (China). Beijing Graduate School

    1994-12-01

    Emission of large amount of SO{sub 2} from combustion of high sulfur coal causes serious environmental pollution. Pre-combustion desulfurization of high sulfur coal has become a necessity. This paper reports test results of fine coal desulfurization with different flotation technology and the effect of pyrite depressant. Test work showed that when the coal sample from Zhong Liang Shau was processed with a Free Jet Flotation Column its pyritic sulfur content was reduced from 3.08% to 0.84%, with 72.22% recovery of combustible matter in clean coal. The concept of Desulfurization Efficiency Index E{sub ds} for comprehensive evaluation of desulfurization process is proposed, which is defined as the product of the ratio of sulfur content reduction of clean coal and the recovery of combustible matters. 6 refs., 4 figs., 3 tabs.

  5. Temperature, salinity, sigma_t, pressure measurement collected using CTD from an unknown platform in the Min Fang Bay from 1984 to 1985 (NODC Accession 0048830)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Southern Ocean data - Min Fang Bay , temperature and salinity measurements collected using CTD from unknown platform in the Min Fang Bay from 1984 to 1985

  6. New wrist bones of Homo floresiensis from Liang Bua (Flores, Indonesia).

    Science.gov (United States)

    Orr, Caley M; Tocheri, Matthew W; Burnett, Scott E; Awe, Rokus Due; Saptomo, E Wahyu; Sutikna, Thomas; Jatmiko; Wasisto, Sri; Morwood, Michael J; Jungers, William L

    2013-02-01

    The carpals from the Homo floresiensis type specimen (LB1) lack features that compose the shared, derived complex of the radial side of the wrist in Neandertals and modern humans. This paper comprises a description and three-dimensional morphometric analysis of new carpals from at least one other individual at Liang Bua attributed to H. floresiensis: a right capitate and two hamates. The new capitate is smaller than that of LB1 but is nearly identical in morphology. As with capitates from extant apes, species of Australopithecus, and LB1, the newly described capitate displays a deeply-excavated nonarticular area along its radial aspect, a scaphoid facet that extends into a J-hook articulation on the neck, and a more radially-oriented second metacarpal facet; it also lacks an enlarged palmarly-positioned trapezoid facet. Because there is no accommodation for the derived, palmarly blocky trapezoid that characterizes Homo sapiens and Neandertals, this individual most likely had a plesiomorphically wedge-shaped trapezoid (like LB1). Morphometric analyses confirm the close similarity of the new capitate and that of LB1, and are consistent with previous findings of an overall primitive articular geometry. In general, hamate morphology is more conserved across hominins, and the H. floresiensis specimens fall at the far edge of the range of variation for H. sapiens in a number of metrics. However, the hamate of H. floresiensis is exceptionally small and exhibits a relatively long, stout hamulus lacking the oval-shaped cross-section characteristic of human and Neandertal hamuli (variably present in australopiths). Documentation of a second individual with primitive carpal anatomy from Liang Bua, along with further analysis of trapezoid scaling relative to the capitate in LB1, refutes claims that the wrist of the type specimen represents a modern human with pathology. In total, the carpal anatomy of H. floresiensis supports the hypothesis that the lineage leading to the

  7. "Glimpses of the Duanwu Festival" by Fang Xun (1736-1799) : commemorative painting or private souvenir ?

    OpenAIRE

    Kerlan-Stephens , Anne

    2001-01-01

    International audience; Fang Xun (1736 or 1737-1799) was a painter from the Hangzhou area who is now known essentially as the author of a treatise on painting, although he enjoyed during his lifetime local artistic fame. This paper details his relationship with a network of friends and clients belonging to the local gentry through the analysis of a painting he realized around 1780, describing a gathering at the estate of his main patron, Jin Deyu (1750-1800).

  8. [On academic thought and clinical application of LI Yan-Fang's middle-warmer energy method].

    Science.gov (United States)

    Li, Li-Jun

    2010-10-01

    The present paper introduces LI Yan-Fang's middle-warmer energy method from acupoint selection, needling methods, treatment principle and his clinical experiences in treatment of stroke and insomnia etc. The acupuncture prescription of this method consist of Shangwan (CV 13), Zhongwan (CV 12), Jianli (CV 11), Xiawan (CV 10), Shuifen (CV 9), Huangshu (KI 16) and Qihai (CV 6) etc as the main acupoints combined with strict manipulation and depth of needling to treat clinical diseases.

  9. The Liang Bua faunal remains: a 95k.yr. sequence from Flores, East Indonesia.

    Science.gov (United States)

    van den Bergh, G D; Meijer, H J M; Due Awe, Rokhus; Morwood, M J; Szabó, K; van den Hoek Ostende, L W; Sutikna, T; Saptomo, E W; Piper, P J; Dobney, K M

    2009-11-01

    Excavations at Liang Bua, a limestone cave on the island of Flores, East Indonesia, have yielded a well-dated archaeological and faunal sequence spanning the last 95k.yr., major climatic fluctuations, and two human species -H. floresiensis from 95 to 17k.yr.(1), and modern humans from 11k.yr. to the present. The faunal assemblage comprises well-preserved mammal, bird, reptile and mollusc remains, including examples of island gigantism in small mammals and the dwarfing of large taxa. Together with evidence from Early-Middle Pleistocene sites in the Soa Basin, it confirms the long-term isolation, impoverishment, and phylogenetic continuity of the Flores faunal community. The accumulation of Stegodon and Komodo dragon remains at the site in the Pleistocene is attributed to Homo floresiensis, while predatory birds, including an extinct species of owl, were largely responsible for the accumulation of the small vertebrates. The disappearance from the sequence of the two large-bodied, endemic mammals, Stegodon florensis insularis and Homo floresiensis, was associated with a volcanic eruption at 17 ka and precedes the earliest evidence for modern humans, who initiated use of mollusc and shell working, and began to introduce a range of exotic animals to the island. Faunal introductions during the Holocene included the Sulawesi warty pig (Sus celebensis) at about 7ka, followed by the Eurasian pig (Sus scrofa), Long-tailed macaque, Javanese porcupine, and Masked palm civet at about 4ka, and cattle, deer, and horse - possibly by the Portuguese within historic times. The Holocene sequence at the site also documents local faunal extinctions - a result of accelerating human population growth, habitat loss, and over-exploitation.

  10. Analysis of Fang Puncture Wound Patterns in Isfahan Province’s, Iran, Venomous and Non-Venomous Snakes

    Directory of Open Access Journals (Sweden)

    Dehghani R.1 PhD,

    2015-01-01

    Full Text Available Aims Venomous snake bites are public health problems in different parts of the world. The most specific mainstay in the treatment of envenomation is anti-venom. To treat the envenomation, it is very important to identify the offending species. This study was designed to determine the penetrating pattern of fangs and teeth of some viper snakes. Materials & Methods This descriptive study was performed on live venomous and nonvenomous snakes from 2010 till 2011. All 47 sample snakes were collected from different regions of Isfahan province such as Kashan City, Ghamsar, Niasar, Mashhad Ardehal, Taher- Abad and Khozagh. Their mouths were inspected every two weeks and development of their fangs and teeth were recorded by taking clear digital photos. Fangs and teeth patterns of samples were drawn and the results were compared. Findings One or two wounds appeared as typical fang marks at the bite site of venomous snakes while non-venomous snakes had two carved rows of small teeth. Three different teeth and fang patterns were recognized in venomous snakes which were completely different. Conclusion The fang marks of venomous snakes do not always have a common and classic pattern and there are at least 3 different patterns in Isfahan province, Iran.

  11. Comments to "Analysis of constant rate period of spray drying of slurry" by Liang et al., 2001

    DEFF Research Database (Denmark)

    Jørgensen, Kåre; Jensen, Anker Degn; Sloth, Jakob

    2006-01-01

    In the study by Liang et al. [2001. Analysis of constant rate period of spray drying of slurry. Chemical Engineering Science 56, 2205-2213] the Darcy flow of liquid through a pore system of primary particles to the surface of a slurry droplet was applied for the constant rate period. Steep primary...... particle concentration gradients inside -25 mu m droplets with a primary particle size of 0.2 mu m were observed. Unfortunately, the boundary condition at the droplet surface for the parabolic second-order PDE did not conserve the solid mass in the droplet, and the plots for the primary particle...

  12. Characteristics of the anti-dementia drug system of Zisu Fang preparations based on pharmacokinetic and pharmacodynamic analysis

    Directory of Open Access Journals (Sweden)

    Jianye Quan

    2017-04-01

    Conclusions: Based on the PK and PD correlation analysis, baicalin, rosmarinic acid, salvianolic acid B, matrine, and tanshinone IIA are the main active ingredients of Zisu Fang preparations with regard to its anti-dementia effects, and represent the basic characteristics of drug system: natures, synergy, and affinity.

  13. The evolving landscape and climate of western Flores: an environmental context for the archaeological site of Liang Bua.

    Science.gov (United States)

    Westaway, K E; Roberts, R G; Sutikna, T; Morwood, M J; Drysdale, R; Zhao, J-x; Chivas, A R

    2009-11-01

    The rapidly changing landscape of the eastern Indonesian archipelago has evolved at a pace dictated by its tropical climate and its geological and tectonic history. This has produced accelerated karstification, flights of alluvial terraces, and complex, multi-level cave systems. These cave systems sometimes contain a wealth of archaeological evidence, such as the almost complete skeleton of Homo floresiensis found at the site of Liang Bua in western Flores, but this information can only be understood in the context of the geomorphic history of the cave, and the more general geological, tectonic, and environmental histories of the river valley and region. Thus, a reconstruction of the landscape history of the Wae Racang valley using speleothems, geological structure, tectonic uplift, karst, cave, and terrace development, provides the necessary evidence to determine the formation, age, evolution, and influences on the site. This evidence suggests that Liang Bua was formed as two subterranean chambers approximately 600ka, but could not be occupied until approximately 190ka when the Wae Racang wandered to the southern side of the valley, exposing the chamber and depositing alluvial deposits containing artifacts. During the next approximately 190k.yr., the chambers coalesced and evolved into a multi-level and interconnected cave that was subjected to channel erosion and pooling events by the development of sinkholes. The domed morphology of the front chamber accumulated deep sediments containing well stratified archaeological and faunal remains, but ponded water in the chamber further prevented hominin use of the cave until approximately 100ka. These chambers were periodically influenced by river inundation and volcanic activity, whereas the area outside the cave was greatly influenced by glacial phases, which changed humid forest environments into grassland environments. This combined evidence has important implications for the archaeological interpretation of the site.

  14. ‘Cultural encounters: Western scholarship and Fang statuary from Equatorial Africa’ [Inaugural address, delivered on the acceptance of an extraordinary professorship at Tilburg University, Netherlands, in 2011

    Directory of Open Access Journals (Sweden)

    Wilfried van Damme

    2014-12-01

    Full Text Available In this inaugural address, delivered on the acceptance of an extraordinary professorship at Tilburg University, Netherlands, in 2011, Wilfried van Damme examines three approaches that have been characteristically applied within the Western anthropology of art during the last half century. Illustrating these approaches with reference to the study of Fang statuary from equatorial Africa, he discusses a stylistic approach, focusing on anatomical details and proportions of Fang anthropomorphic sculptures; a culturalist approach, highlighting the local meaning and values these sculptures express; and a postcolonial approach, dealing with the Western appropriation and commodification of Fang statues.

  15. [Textual research on circulation of the Ming edition of Li Heng's Xiu zhen fang (Pocket Formulary)].

    Science.gov (United States)

    Yang, Jinping; Liu, Peng; Lu, Mingjing; Lu, Xing; Li, Shaolin; Jin, Xiumei

    2015-03-01

    Xiu zhen fang (Pocket Formulary) is a recipe book of the Ming Dynasty, inspired and managed by Zhu Su, compiled by Li Heng of liangyisuo (good physician house) in Zhou wangfu (Zhou's royal palace). The book was compiled and published twice during the reigns of the Hongwu and Yongle Emperors of the Ming Dynasty. Because of its high practicability, there were some editions in circulation, and the book was published several times only in the Ming Dynasty. At present, the earliest extanteditionwas the little character version of Yongle, and the version in the 4(th) year of Zhengde Emperor of the Ming Dynasty was a reprinting edition based on the Yongle edition, sharingthe same edition system. Most of the editions appeared after the reign of Zhengtong Emperor of the Ming Dynasty, titled by "kui ben (head version)" and "da quan (complete edition)" were the editionspublished in the local bookshops, which had rather distinct differences from the Yongle edition system not only in the its format but also in its contents.

  16. Inhibitory effect of bofutsushosan (fang feng tong sheng san) on glucose transporter 5 function in vitro.

    Science.gov (United States)

    Gao, Shengli; Satsu, Hideo; Makino, Toshiaki

    2018-03-01

    Bofutsushosan (BTS; fang feng tong sheng san in Chinese) is a formula in traditional Japanese Kampo medicine and Chinese medicine comprising eighteen crude drugs, and is used to treat obesity and metabolic syndrome. Fructose is contained in refreshing beverages as high-fructose corn syrup, and is associated with obesity. Fructose is absorbed via glucose transporter 5 (GLUT5) in the intestine. Therefore, the inhibition of GLUT5 is considered to be a target of obesity drugs. We evaluated the inhibitory effects of BTS extract and its constituents on fructose uptake using Chinese hamster ovary K1 cells, i.e., cells stably expressing GLUT5. Boiled water extract of BTS significantly suppressed GLUT5 function in a concentration-dependent manner without cytotoxicities. Among 18 components of BTS, the boiled water extracts of the rhizome of Zingiber officinale, the root and rhizome of Saposhnikovia divaricata, and the root of Platycodon grandiflorum exhibited significant inhibitory effects on fructose uptake with IC 50 values of 314, 119 and 475 µg/ml, respectively. Among the constituents of the rhizome of Z. officinale extract, 6-gingerol significantly inhibited GLUT5 with an IC 50 value of 39 µM, while 6-shogaol exhibited a significant but weak inhibition on GLUT5 at 100 µM. One of the mechanisms of action of BTS may be the inhibition of fructose absorption in the intestine, and one of the active components of BTS is the rhizome of Z. officinale and 6-gingerol.

  17. [Decipherment and annotation of some terms in the remnant scrolls of Hui hui yao fang (Huihui Formularies)].

    Science.gov (United States)

    Huang, Y; Wang, J

    2017-05-28

    The etymology of the terms in Hui hui yao fang ( Huihui Formularies ) is complicated. Their origin might be Arabian, Persian, or Sanskrit, or even the northern dialects of Han language during the Yuan and Ming Dynasties. There are obvious mistakes or indefinite decipherments and interpretations of the terms in Song Xian's Investigated Annotations of Huihui Formularies . There are also missing annotations for those transliterated terms. To tackle such defects, 12 such terms are deciphered and annotated here.

  18. The Relation of Personal Hygiene with The Incidence of Scabies at Al Falah Male Boarding School Students Sub-district of Liang Anggang in the Year 2016

    Directory of Open Access Journals (Sweden)

    Nur Muafida

    2017-04-01

    Full Text Available Poor personal hygiene can be a factor supporting the development of skin diseases such as scabies. In Indonesia the scabies disease numerous in boarding school. One of the things that support the transmission of scabies is personal hygiene students who are not good. The study aimed to determine the relationship of personal hygiene with the incidence of scabies on students Al Falah male boarding school students at sub-district of Liang Anggang in the year 2016. This research is an analytic observational  with cross sectional design. The sample of research are students of Al Falah for boys boarding school Sub-district of Liang Anggang as many as 127 people. Data analysis using statistical Chi-square test (X2. The results showed among 127 students, 59 of them in a poor condition of personal hygiene 53 of them categorized affected with scabies (89.8 %. While the remaining 68 students were in a good condition of personal hygiene with 23 of them having scabies (33.8%. X2 test results showed that there was a significant relationship, personal hygiene with the incidence of scabies on students boarding school Al Falah for boys Sub-district of Liang Anggang in the year 2016 at p-value = 0.000. Efforts should be made to reduce the incidence of scabies among others: showering twice a day using clean water, use personal belongings are not mutually borrowing, keep clean hands and nails, hygiene clothing and cleanliness of the bed.

  19. New ceramic data from East Kalimantan : the cord-marked and red-slipped sherds of Liang Abu's layer 2 and Kalimantan's potter chronology

    International Nuclear Information System (INIS)

    Plutniak, S.; Agus Oktaviana, A.; Sugiyanto, B.; Chazine, J.M.; Ricaut, F.X.

    2014-01-01

    Archaeological research in the Liang Abu rock shelter (East Kalimantan) led to the discovery and analysis of a pottery assemblage including red-slipped, cord-marked and incised pottery sherds, radiocarbon dated to 1672 ± 21 BP and 1524 ± 22 BP. In order to discuss our findings we undertake a reappraisal of the pottery material and associated radiocarbon dates from archaeological sites on Borneo Island, which provide us with an appropriate framework for a comparative analysis. This allows us to to include the inland region of Kalimantan in the technological network of Neolithic Island South East Asia. (author)

  20. Le corpus lexicographique dans les langues à tradition orale: le cas du dialecte fang-mekè*

    Directory of Open Access Journals (Sweden)

    Nzang-Bié Yolande

    2011-10-01

    Full Text Available

    Résumé: Les corpus sont à la base de la plupart des recherches en linguistique et particulièrementlexicographique. La compilation d'un corpus est une activité spécialisée dont dépend lerésultat de la recherche en question. Le sujet de cet article est la compilation du corpus lexicographiquedans les langues à tradition orale, et exige une démarche différente de celle ayant unelongue tradition écrite. De ce fait, ces dernières disposent d'une importante documentationpouvant servir comme base pour de nombreux sujets de recherche. L'auteur propose commeapproche une analyse qui permettrait de mieux rendre compte des spécificités lexicales etsémantiques des langues à tradition orale.Par le truchement de la production orale libre, l'auteur base ses hypothèses de recherche surune expérience en dialecte fang-mekè, une variante linguistique localisée au Gabon. Les résultatspermettent de mettre l'accent sur deux données essentielles du processus de compilation dans leslangues à tradition orale: les informateurs et la représentativité du corpus. Cette dernière, qui doits'exprimer à travers des champs lexicaux diversifiés mais également équilibrés, permettrait d'élaborerdes dictionnaires dans lesquels les locuteurs, qui en sont les premiers utilisateurs, doivent sereconnaître.

    Mots-clés: CORPUS, LEXICOGRAPHIE, LANGUES À TRADITION ORALE, LANGUES ÀTRADITION ÉCRITE, INFORMATEURS, EXHAUSTIVITÉ, REPRÉSENTATIVITÉ, CHAMPSLEXICAUX, ORALITÉ, ÉCRITURE, MÉTHODE, DIALECTE FANG-MEKÈ, CORPUS ÉQUILIBRÉ.

    Abstract: The Lexicographic Corpus in Languages with an Oral Tradition: The Case of the Dialect Fang-Mek?. Corpora form the basis of most linguistic and especially lexicographic research. The compilation of a corpus is a specialised activity on which depends the result of the research to be undertaken. The subject of this article is the compilation of a lexicographic corpus in languages with an oral tradition

  1. [Bushen Huoxue Fang promotes the apoptosis of epithelial cells in the prostatic ductal system of rats with benign prostatic hyperplasia].

    Science.gov (United States)

    Sun, Jie; Li, Qiu-Fen; Tian, Dai-Zhi; Jiang, Shao-Bo; Wu, Xian-De; Qiu, Shun-An; Ren, Xiao-Gang; Li, Yu-Bing

    2014-09-01

    To investigate the effects of Bushen Huoxue Fang (BSHX) on the apoptosis of epithelial cells in the prostatic ductal system of rats with benign prostatic hyperplasia (BPH) and its possible action mechanism. One hundred 3- month-old male Wistar rats were randomly divided into four groups of equal number (control, castrated, BPH model, and BSHX). BPH models were made by subcutaneous injection of testosterone following castration; the rats in the BSHX group were treated intragastrically with BSHX at 2.34 g/ml after modeling, while those in the other two groups with equal volume of saline, all for 37 days. On the 38th day, all the rats were sacrificed and their prostates harvested for detection of the distribution of TGF-beta1 and alpha-actin and the count of positive cells in the prostatic ductal system by immunohistochemical staining. The apoptosis rate of epithelial cells in the prostatic ductal system was determined by TUNEL assay. The expression of TGF-beta1 was significantly increased in the rats of the BSHX group as compared with the BPH models in both the proximal prostatic duct ([15.28 +/- 4.30]% vs [36.42 +/- 8.10]%, P epithelial cells in the proximal prostatic duct ([39.42 +/- 9.20]% vs [3.86 +/- 1.34]%, P epithelial cells in the prostatic ductal system was significantly higher in the BSHX-treated rats than in the BPH models (P epithelial cells, and thus effectively inhibit benign prostatic hyperplasia.

  2. The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota

    Directory of Open Access Journals (Sweden)

    Shu Liang

    2018-01-01

    Full Text Available The present study investigates the potential therapeutic mechanism underlying the effects of the Chinese herbal formula Hongqijiangzhi Fang (HJF on nonalcoholic fatty liver disease (NAFLD in rats. Male Sprague Dawley (SD rats were randomly divided into 4 groups (n=8: control group was fed a normal diet, three other groups were fed high-fat diets (HFD, and the two treatment groups were intragastrically given a compound probiotic or HJF during the molding time. After 16 w, related indices were detected. The results showed that HJF significantly reduced abdominal aorta serum cholesterol (TC, triglyceride (TG, low-density lipoprotein (LDL, IL-1β, and IL-18, portal venous serum lipopolysaccharide (LPS, and liver TC and TG levels in HFD-fed rats. HJF ameliorated hepatic steatosis in the liver and improved the intestinal barrier in HFD-fed rats. Activation of the NLRP3 inflammasome was reduced by HJF in HFD-fed rats. Additionally, the abundances of A. muciniphila (Verrucomicrobiaceae, F. rappini (Helicobacteraceae, and Enterobacteriaceae bacteria significantly decreased in HJF-treated HFD-fed rats. In conclusion, these result suggested that the Chinese herbal formula HJF reduced hepatic steatosis maybe through decreasing certain gut bacteria (such as Enterobacteriaceae bacteria and F. rappini, alleviating intestinal endotoxemia and reducing NLRP3 inflammasome activation.

  3. A generalized nonlinear tempeature response function for some growth and developmental parameters in kiwifruit (Actinidia deliciosa (A. Chev. C. F. Liang & A. R. Ferguson

    Directory of Open Access Journals (Sweden)

    Streck Nereu Augusto

    2003-01-01

    Full Text Available Temperature is a major factor that affects metabolic processes in living organisms. Thermal time has been widely used to account for the effects of temperature on crop growth and development. However, the thermal time approach has been criticized because it assumes a linear relationship between the rate of crop growth or development and temperature. The response of the rate of crop growth and development to temperature is nonlinear. The objective of this study was to develop a generalized nonlinear temperature response function for some growth and developmental parameters in kiwifruit (Actinidia deliciosa (A. Chev. C. F. Liang & A. R. Ferguson. The nonlinear function has three coefficients (the cardinal temperatures, which were 0ºC, 25ºC, and 40ºC. Data of temperature response of relative growth rate, relative leaf area growth, net photosynthesis rate, and leaf appearance rate in kiwifruit (female cv. Hayward at two light levels, which are from published research, were used as independent data for evaluating the performance of the nonlinear and the thermal time functions. The results showed that the generalized nonlinear response function is better than the thermal time approach, and the temperature response of several growth and developmental parameters in kiwifruit can be described with the same response function.

  4. Una aportación al estudio del cuento fang de Guinea Ecuatorial en lengua española / A CONTRIBUTION TO THE STUDY ABOUT THE FANG TALES FROM EQUATORIAL GUINEA IN SPANISH LANGUAGE

    Directory of Open Access Journals (Sweden)

    María Teresa Abaga Envó

    2009-06-01

    Full Text Available Resumen: Una lectura sobre los estudios narratológicos revela que el acto narrativo es un hecho consustancial al ser humano. “Somos el homo sapiens, porque somos el homo narrans”, diría el académico José María Merino (2002: 57. De las estructuras narrativas, el cuento oral tradicional se alza como la forma más antigua. Tan antigua y presente en todos los pueblos que componentes semánticos y formales se repiten en relatos de distintas culturas. Tales aspectos constituyen el objeto de análisis de este repertorio de cuentos fantásticos de Guinea Ecuatorial transmitidos en lengua española. En dicho entorno, el cuento oral fang se manifiesta como un arte viviente. No es un evento pensado sólo para niños; toda la comunidad participa de esta “fiesta” que se verá enaltecida por la presencia del canto. Dada la escasa proliferación de estudios del relato oral africano y en particular del guineano, se hace imperativo partir de estudios occidentales, lo cual nos desliza hacia el terreno del comparativismo. Sin embargo, no siempre dichos estudios son confirmados en esta investigación que concluye con las siguientes tesis: el criterio verdad y ficción al que se recurre para delimitar ciertas narraciones tradicionales europeas queda difuminado; uso irregular de las fórmulas de abertura y cierre; la asignación del fin lúdico de los cuentos fantásticos se acompaña del didáctico y la pretendida universalización del método estructuralista formal de Vladimir Propp, expuesta en Morfología del cuento (1987, se vislumbra inoperante, pues quedan reducidas las treinta y una funciones y la sucesión lineal de las mismas. Los temas y los motivos, arropados por el espíritu de la cultura donde emergen, son similares a los identificados en compilaciones españolas o internacionales. Finalmente, la naturaleza oral tradicional del repertorio queda patente a través de las nueve “Leyes Épicas” establecidas por Axel Orlik (1965: la Ley de

  5. TWO NEW RECORDS OF Isomyia paurogonita FANG AND FAN, 1986 AND Sumatria latifrons Malloch, 1926 (DIPTERA: CALLIPHORIDAE FROM NORTHERN THAILAND, WITH REVISED KEY TO THE SPECIES OF Isomyia

    Directory of Open Access Journals (Sweden)

    Nophawan Bunchu

    2014-04-01

    Full Text Available During the annual fly survey at Doi Nang Kaew in Doi Saket District, Chiang Mai Province of Thailand in 2011, Isomyia paurogonita Fang & Fan, 1986 (Diptera: Calliphoridae and Sumatria latifrons Malloch, 1926 (Diptera: Calliphoridae were collected for the first time in Thailand. They are the rare species of the subfamily Rhiniinae (tribe Cosminini. Prior to this finding, fifteen species of Isomyia and two species of Sumatria were recorded from Thailand. Therefore, 96 blow fly species have been found in this country. These new locality records of both flies are very important for further research on their biology and ecology in Thailand.

  6. Transcriptomics-guided bottom-up and top-down venomics of neonate and adult specimens of the arboreal rear-fanged Brown Treesnake, Boiga irregularis, from Guam.

    Science.gov (United States)

    Pla, Davinia; Petras, Daniel; Saviola, Anthony J; Modahl, Cassandra M; Sanz, Libia; Pérez, Alicia; Juárez, Elena; Frietze, Seth; Dorrestein, Pieter C; Mackessy, Stephen P; Calvete, Juan J

    2018-03-01

    The Brown Treesnake (Boiga irregularis) is an arboreal, nocturnal, rear-fanged venomous snake native to northern and eastern regions of Australia, Papua New Guinea and the Solomon Islands. It was inadvertently introduced onto the island of Guam during the late 1940's to early 1950's, and it has caused massive declines and extirpations of the native bird, lizard, and mammal populations. In the current study, we report the characterization of the venom proteome of an adult and a neonate B. irregularis specimens from Guam by a combination of venom gland transcriptomic and venomic analyses. Venom gland transcriptomic analysis of an adult individual identified toxins belonging to 18 protein families, with three-finger toxin isoforms being the most abundantly expressed transcripts, comprising 94% of all venom protein transcript reads. Transcripts for PIII-metalloproteinases, C-type lectins, cysteine-rich secretory proteins, acetylcholinesterases, natriuretic peptides, ficolins, phospholipase A 2 (PLA 2 ) inhibitors, PLA 2 s, vascular endothelial growth factors, Kunitz-type protease inhibitors, cystatins, phospholipase Bs, cobra venom factors, waprins, SVMP inhibitors, matrix metalloproteinases, and hyaluronidases were also identified, albeit, at very low abundances ranging from 0.05% to 1.7% of the transcriptome. The venom proteomes of neonate and adult B. irregularis were also both overwhelmingly (78 and 84%, respectively) dominated by monomeric and dimeric 3FTxs, followed by moderately abundant (21% (N) and 13% (A)) CRISPs, low abundance (1% (N), 3% (A)) PIII-SVMPs, and very low abundance (blot analysis showed that all venom proteins were recognized by anti-BTS IgGs, and cross-reactivity with other rear-fanged snake venoms was also observed. Incubation of anti-BTS venom IgGs with crude B. irregularis venom resulted in a significant decrease in proteolytic (SVMP) activity against azocasein. These results provide the first comparative venomic and anti-venomic analysis of

  7. Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells

    Directory of Open Access Journals (Sweden)

    Li JY

    2016-04-01

    Full Text Available Jingya Li,1,* Ruizhen Zhao,1,* Xiaoli Li,1 Wenjun Sun,1 Miao Qu,1 Qisheng Tang,1 Xinke Yang,1 Shujing Zhang2 1Third Affiliated Hospital, 2School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Shen-Qi-Jie-Yu-Fang (SJF is composed of eight Chinese medicinal herbs. It is widely used in traditional Chinese medicine for treating postpartum depression (PPD. Previous studies have shown that SJF treats PPD through the neuroendocrine mechanism. Aim: To further investigate the effect of SJF on the immune system, including the inflammatory response system and CD4+CD25+ regulatory T (Treg cells. Materials and methods: Sprague Dawley rats were used to create an animal model of PPD by inducing hormone-simulated pregnancy followed by hormone withdrawal. After hormone withdrawal, the PPD rats were treated with SJF or fluoxetine for 1, 2, and 4 weeks. Levels of Treg cells in peripheral blood were measured by flow cytometry analysis. Serum interleukin (IL-1β and IL-6 were evaluated by enzyme-linked immunosorbent assay, and gene and protein expressions of IL-1RI, IL-6Rα, and gp130 in the hippocampus were observed by reverse-transcription polymerase chain reaction and Western blot. Results: Serum IL-1β in PPD rats increased at 2 weeks and declined from then on, while serum IL-6 increased at 1, 2, and 4 weeks. Both IL-1β and IL-6 were downregulated by SJF and fluoxetine. Changes in gene and protein expressions of IL-1RI and gp130 in PPD rats were consistent with changes in serum IL-1β, and were able to be regulated by SJF and fluoxetine. The levels of Treg cells were negatively correlated with serum IL-1β and IL-6, and were decreased in PPD rats. The levels of Treg cells were increased by SJF and fluoxetine. Conclusion: Dysfunction of proinflammatory cytokines and Tregs in different stages of PPD was attenuated by SJF and fluoxetine through

  8. Effects of Qi-Fang-Xi-Bi-Granules on Cartilage Morphology and C/ebpα Promoter Methylation in Rats with Knee Osteoarthritis

    Directory of Open Access Journals (Sweden)

    Xinxin Wang

    2018-01-01

    Full Text Available Objective. To investigate the effects of Qi-Fang-Xi-Bi-Granules (QFXBGs on cartilage morphology and methylation of C/ebpα (CCAAT/enhancer binding proteinα at the promoter region. Methods. Knee osteoarthritis (KOA modeling was performed in rats in accordance with Hulth’s method, and control group received sham operation. Eight weeks after KOA modeling, the rats in the KOA modeling group were further divided into 6 groups. Each group was given the appropriate drug. After 8 weeks, half of the rats were used for Micro-CT scan, HE staining, ABH/OG staining, immunohistochemistry, and TUNNEL staining of the knee joint tissue, and the other half were used to examine C/ebpα promoter methylation. Results. The three dose groups of QFXBGs all showed lower degrees of surface fissures and flaking, thicker cartilage layer, and restored chondrocyte and subchondral bone morphology, compared with the KOA model group. C/ebpα-22 promoter methylation levels in the high- and low-dose groups were significantly higher than that in the KOA modeling group (p<0.05, while C/ebpα-2 promoter methylation level in the medium-dose group was significantly higher than that in the KOA modeling group (p<0.05. Conclusions. QFXBGs may alleviate articular cartilage degeneration through promoting C/ebpα-2 or C/ebpα-22 methylation at specific promoter sites.

  9. On-line monitoring the extract process of Fu-fang Shuanghua oral solution using near infrared spectroscopy and different PLS algorithms

    Science.gov (United States)

    Kang, Qian; Ru, Qingguo; Liu, Yan; Xu, Lingyan; Liu, Jia; Wang, Yifei; Zhang, Yewen; Li, Hui; Zhang, Qing; Wu, Qing

    2016-01-01

    An on-line near infrared (NIR) spectroscopy monitoring method with an appropriate multivariate calibration method was developed for the extraction process of Fu-fang Shuanghua oral solution (FSOS). On-line NIR spectra were collected through two fiber optic probes, which were designed to transmit NIR radiation by a 2 mm flange. Partial least squares (PLS), interval PLS (iPLS) and synergy interval PLS (siPLS) algorithms were used comparatively for building the calibration regression models. During the extraction process, the feasibility of NIR spectroscopy was employed to determine the concentrations of chlorogenic acid (CA) content, total phenolic acids contents (TPC), total flavonoids contents (TFC) and soluble solid contents (SSC). High performance liquid chromatography (HPLC), ultraviolet spectrophotometric method (UV) and loss on drying methods were employed as reference methods. Experiment results showed that the performance of siPLS model is the best compared with PLS and iPLS. The calibration models for AC, TPC, TFC and SSC had high values of determination coefficients of (R2) (0.9948, 0.9992, 0.9950 and 0.9832) and low root mean square error of cross validation (RMSECV) (0.0113, 0.0341, 0.1787 and 1.2158), which indicate a good correlation between reference values and NIR predicted values. The overall results show that the on line detection method could be feasible in real application and would be of great value for monitoring the mixed decoction process of FSOS and other Chinese patent medicines.

  10. Determination of the phytochemical composition of Jingning fang and the in vivo pharmacokinetics of its metabolites in rat plasma by UPLC-MS/MS.

    Science.gov (United States)

    Yang, Chunjing; Yin, XingBin; Dong, Xiaoxv; Zhang, Xin; You, Longtai; Wang, Wenping; Wang, Junhong; Chen, Qinghe; Ni, Jian

    2017-11-01

    Jingning fang (JNF) is an effective Traditional Chinese Medicine (TCM) which is used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). To clarify the bioactive constituents of JNF, a Thermo Q Exactive™ Plus Orbitrap™ mass spectrometer was used in this study. More than 127 chemical compounds were isolated and identified tentatively in the JNF extract, while 42 prototype constituents with 4 potential metabolites were identified tentatively in rat plasma. A method for simultaneous determination of polygalaxanthone III (PAIII), sibiricose A 5 (A 5 ), sibiricose A 6 (A 6 ), 3, 6'-disinapoyl sucrose (3,6'-DISS), tenuifoliside C (TEC), tenuifolin B (TNB), verbascoside (VCE), heterophyllin B (HEB) and schisandrin (SCH) in rat was developed and validated using polydatin (PLN) and psoralen (PSN) as internal standards. All calibration curves proved favorable linearity (R 2 ≥0.9923) in linear ranges. The lower limit of quantification (LLOQ) was 2.5ng/mL for PAIII, A 5 , 3, 6'-DISS, TNB, VCE, HEB and SCH, 1.0ng/mL for A 6 and TEC, respectively. Intra-day and inter-day precisions didn't exceed 14.0% for all the analytes. Extraction recoveries and matrix effects of analytes and IS were acceptable. The validated method has been successfully applied to the pharmacokinetics (PK) studies of the nine compounds in JNF. These findings are useful for predicting the bioactive components of JNF, and will aid in optimizing dose regimens of the drug. Copyright © 2017. Published by Elsevier B.V.

  11. Chemical profiles and pharmacological activities of Chang-Kang-Fang, a multi-herb Chinese medicinal formula, for treating irritable bowel syndrome.

    Science.gov (United States)

    Mao, Qian; Shi, Lei; Wang, Zhi-Gang; Luo, Yu-Hui; Wang, Yin-Yu; Li, Xue; Lu, Min; Ju, Jian-Min; Xu, Jin-Di; Kong, Ming; Zhou, Shan-Shan; Shen, Min-Qin; Li, Song-Lin

    2017-04-06

    Chang-Kang-Fang formula (CKF), a multi-herb traditional Chinese medicinal formula, has been clinically used for treatment of irritable bowel syndrome (IBS). The mechanisms of CKF for treating IBS and the components that are responsible for the activities were still unknown. To investigate the chemical profiles and effects of CKF on IBS model. The chemical profiles of CKF were investigated by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-Q/TOF-MS/MS). On colon irritation induced rat neonates IBS model, the influence of CKF on neuropeptides, including substance P (SP), calcitonin gene-related peptide (CGRP), vasoactive intestinal polypeptide (VIP) and 5-hydroxytryptamine (5-HT), were measured by ELISA, and the effect on intestinal sensitivity was assessed based on the abdominal withdrawal reflex (AWR) scores. In addition, the activities of CKF against acetic acid-induced nociceptive responses and prostigmin methylsulfate triggered intestinal propulsion in mice were also evaluated. 80 components were identified or tentatively assigned from CKF, including 11 alkaloids, 20 flavanoids, 4 monoterpenoids, 9 iridoid glycoside, 9 phenylethanoid glycosides, 10 chromones, 7 organic acid, 3 coumarins, 2 triterpene and 5 other compounds. On IBS rat model, CKF was observed to reduce AWR scores and levels of SP, CGRP, VIP and 5-HT. Moreover, CKF reduced the acetic acid-induced writhing scores at all dosages and reduced the intestinal propulsion ration at dosage of 7.5 and 15.0g/kg/d. CKF could alleviate the symptoms of IBS by modulating the brain-gut axis through increasing the production of neuropeptides such as CGRP, VIP, 5-HT and SP, releasing pain and reversing disorders of intestinal propulsion. Berberine, paeoniflorin, acteoside, flavonoids and chromones may be responsible for the multi-bioactivities of CKF. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  12. Herbal medicine Guan Chang Fu Fang enhances 5-fluorouracil cytotoxicity and affects drug-associated genes in human colorectal carcinoma cells.

    Science.gov (United States)

    Yu, Chen; Liu, Shen-Lin; Qi, Ming-Hao; Zou, Xi; Wu, Jian; Zhang, Jing

    2015-02-01

    Guan Chang Fu Fang (GCFF) is a natural compound, which is extracted from three medicinal plants, Agrimonia pilosa Ledeb ., Patrinia scabiosaefolia and Solanum nigrum L . GCFF has demonstrated clinical efficacy in the treatment of colon cancer. At present, 5-fluorouracil (5-FU) is the primary active chemotherapeutic agent used for treating colon cancer. Using median-effect and apoptosis analyses, fluorescence microscopy and western blotting, the present study analyzed the association between GCFF and 5-FU in the human colon adenocarcinoma LoVo cell line. The effect of GCFF on the expression of chemotherapeutic agent-associated genes was also investigated. The results of the synergistic analysis revealed that GCFF exhibited a significant effect upon 5-FU-associated cytotoxicity within the LoVo cell line. This effect was observed over a broad dose-inhibition range (5-95%), but was particularly significant in the lower concentrations. The flow cytometry results revealed that low doses of GCFF or 5-FU induced S-phase arrest, as did a low-dose combination of the two drugs. After 48 h, GCFF significantly suppressed the expression levels of the chemotherapeutic agent resistance-associated genes within the colon cancer cells. The western blot analysis revealed that the combined effects of 5-FU and GCFF were due to a regulation of the B-cell lymphoma-2 family of proteins. The findings of the present study suggested that GCFF, when combined with 5-FU, has the potential to be a novel, chemotherapeutic compound for the treatment of colon cancer.

  13. Fang CO2 med Aminosyrer

    DEFF Research Database (Denmark)

    Lerche, Benedicte Mai

    2010-01-01

    Med såkaldte “carbon capture-teknikker” er det muligt at rense røgen fra kulfyrede kraftværker, således at den er næsten helt fri for drivhusgassen CO2. Kunsten er at gøre processen tilstrækkeligt billig. Et lovende fangstredskab i denne proces er aminosyrer.......Med såkaldte “carbon capture-teknikker” er det muligt at rense røgen fra kulfyrede kraftværker, således at den er næsten helt fri for drivhusgassen CO2. Kunsten er at gøre processen tilstrækkeligt billig. Et lovende fangstredskab i denne proces er aminosyrer....

  14. DONG JIE Zhang, LIANG Wang, ZHON

    Indian Academy of Sciences (India)

    User

    development, hairless nude skin, and short life (Abitbol et al., 2015; Bryson et al., 2013). On the ... Foxn1 maintains TECs to support T-cell development via mcm2 ... were ligated upstream of the firefly luciferase gene in the plasmid pGL3-Basic.

  15. Blazar Sequence in Fermi Era Liang Chen

    Indian Academy of Sciences (India)

    Abstract. In this paper, we review the latest research results on the topic of blazar sequence. It seems that the blazar sequence is phenomenally ruled out, while the theoretical blazar sequence still holds. We point out that black hole mass is a dominated parameter accounting for high-power- high-synchrotron-peaked and ...

  16. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Hai-Liang Zhu. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 463-470. Synthesis, antimicrobial activity of lamotrigine and its ammonium derivatives · Yong Qian Peng-Cheng Lv Lei Shi Rui-Qin Fang Zhong-Cheng Song Hai-Liang Zhu.

  17. Influence of Jiang Tang Bu Shen Fang on expression of IKKβ mRNA in diabetic rats%降糖补肾方对糖尿病大鼠IKKβ mRNA表达的影响

    Institute of Scientific and Technical Information of China (English)

    范冠杰; 孙晓泽; 唐咸玉; 孙璐; 曾星; 罗广波; 卢绮韵; 温建炫

    2011-01-01

    目的 观察降糖补肾方对小剂量链脲佐菌素(STZ)加高脂饲料诱导的糖尿病模型大鼠肌肉组织IKK激酶β(IKKβ)信使核糖核酸(mRNA)表达的影响.方法 雄性SD大鼠高脂饲料喂养4周后注射小剂量STZ,1周后测大鼠空腹血糖,血糖值>11.1 mmoL/L者为造模成功的大鼠,将造模成功的大鼠随机分为模型组和降糖补肾方干预组,另设阿司匹林对照组和空白对照组,药物干预4周,取大腿肌肉组织,采用聚合酶链反应逆转录RT-PCR技术检测IKKβ mRNA表达水平.结果 模型组IKKβ mRNA表达明显高于空白对照组,是空白对照组的5.098倍(P0.05.结论 降糖补肾方在一定程度上能抑制糖尿病大鼠IKKβ mRNA基因,这可能是降糖补肾方抑制炎症信号通路的传导而发挥其改善胰岛素抵抗治疗糖尿病的机制之一.%Objective To observe the influence of Jiang Tang Bu Shen Fang on the expression of I kappa P kinase (IKKp) mRNA in muscular tissue in diabetic rats induced by low-dose streptozotocin ( STZ) and high-fat diet (HFD). Methods Male SD rats were fed HFD for 4 weeks, and then injected low-dose STZ. After one week the level of fasting plasma glucose was detected in rats and those with higher than 11. 1 mmol/L of level of fasting plasma glucose were successfully modeled. The rats were randomly divided into the model group, low-dose, mid-dose and high-dose Jiang Tang Bu Shen Fang groups (low-dose, mid-dose and high-dose groups), aspirin group and blank group. All groups were intervened by relevant medicinal for 4 weeks. The expression of IKKp mRNA in muscular tissue was detected by using reverse transcription polymerase chain reaction (RT-PCR). Results The expression of IKKp mRNA in the model group was significantly higher than that in the blank group (5.098 times, P 0. 05 compared with that in the model group. Conclusion Jiang Tang Bu Shen Fang can inhibit IKK(3 mRNA to some extent in diabetic rats, which may be one of mechanisms of the

  18. 78 FR 14556 - Cheng Yi Liang: Debarment Order

    Science.gov (United States)

    2013-03-06

    .... 1001 and securities fraud, a Federal felony offense under 15 U.S.C. 78j(b) and 78ff. FDA's finding that debarment is appropriate is based on the felony conviction for securities fraud referenced herein for... execution of trades on national securities exchanges, resulting in total profits and losses avoided of $3...

  19. Health Benefits of Theanine in Green Tea: A Review | Liang ...

    African Journals Online (AJOL)

    Theanine is an amide exclusively present in tea and some fungi, and is an important bioactive component of tea. The bioactive effects of theanine include antitumour, anti-diabetic, antihypertensive, anti-stress activities, and the ability to improve cardiovascular and cerebrovascular diseases. It also has protective effect on ...

  20. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Acupuncture in Treating Hepatic Fibrosis: A Review with Recommendation for Future Studies · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J Zhou, Y Liang, XM Lin, RJ Ma, JQ Fang, 452-458. http://dx.doi.org/10.4314/ajtcam.v9i4.1 ...

  1. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Schinzel–Giedion syndrome: a novel case, review and revised diagnostic criteria · WEI-LIANG LIU ZHI-XU HE FANG LI RONG AI HONG-WEI MA · More Details Abstract Fulltext PDF. Schinzel–Giedion syndrome (SGS) is a rare autosomal dominant inheritance disorder. Heterozygous de novo mutations in the SETBP1 gene ...

  2. Non-front-fanged colubroid ("colubrid") snakebites: three cases of local envenoming by the mangrove or ringed cat-eyed snake (Boiga dendrophila; Colubridae, Colubrinae), the Western beaked snake (Rhamphiophis oxyrhynchus; Lamprophiidae, Psammophinae) and the rain forest cat-eyed snake (Leptodeira frenata; Dipsadidae).

    Science.gov (United States)

    Weinstein, S A; Griffin, R; Ismail, A K

    2014-04-01

    Non-front-fanged colubroid snakes (NFFC; formerly and artificially taxonomically assembled as "colubrids") comprise the majority of extant ophidian species. Although the medical risks of bites by a handful of species have been documented, the majority of these snakes have oral products (Duvernoy's secretions, or venoms) with unknown biomedical properties/unverified functions and their potential for causing harm in humans is unknown. Described are three cases of local envenoming from NFFC bites inflicted respectively by the mangrove or ringed cat-eyed snake (Boiga dendrophila, Colubridae), the Western beaked snake (Rhamphiophis oxyrhynchus, Lamprophiidae) and the rain forest cat-eyed snake (Leptodeira frenata, Dipsadidae). The effects ranged from mild pain, edema and erythema to severe pain, progressive edema, and blistering with slowly resolving arthralgia; there were no systemic effects. Although these three taxa occasionally inflict bites with mild to moderate local effects, there is no current evidence of systemic involvement. Two of these cases were reported to one of the authors for medical evaluation, and although verified, thus constitute reliably reported cases, but low-quality evidence. Type-1 local hypersensitivity may contribute to some cases, but most local effects observed or reported in these three cases were consistent with the effects of venom/oral product components.

  3. Effect of Songyu Anshen Fang on expression of hypothalamic GABA ...

    African Journals Online (AJOL)

    Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. Available online ... GABA and GABA(B) receptor proteins in insomniac rats induced by ..... induced by PCPA; ***p < 0.001 vs Saline group ; ###p.

  4. From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy

    DEFF Research Database (Denmark)

    Laustsen, Andreas Hougaard; Engmark, Mikael; Milbo, Christina

    2016-01-01

    The snake is the symbol of medicine due to its association with Asclepius, the Greek God of medicine, and so with good reasons. More than 725 species of venomous snakes have toxins specifically evolved to exert potent bioactivity in prey or victims, and snakebites constitute a public health hazar...

  5. Modulation of epithelial sodium channel in human alveolar epithelial ...

    African Journals Online (AJOL)

    Modulation of epithelial sodium channel in human alveolar epithelial cells by lipoxin A4 through AhR-cAMP-dependent pathway. Bi-Huan Cheng1,2, Li-Wei Pan2, Sheng-Rong Zhang3, Bin-Yu Ying2, Ben-Ji. Wang2, Guo-Liang Lin2 and Shi-Fang Ding1*. 1Department of Critical Care Medicine, Qilu Hospital of Shandong ...

  6. Liang et al., Afr J Tradit Complement Altern Med. (2016) 13(5):33-37 ...

    African Journals Online (AJOL)

    AN EXPERIMENTAL STUDY ON BIASED COGNITIVE PROCESSING IN ... for its high incidence and disability rate, is easy to cause serious psychological problems ..... processing characteristics of the injured at different levels of development.

  7. Liang et al., Afr J Tradit Complement Altern Med. (2016) 13(3):209 ...

    African Journals Online (AJOL)

    Methods and Materials: High fat diet induced diabetic KKAy mice were administered with phloridzin at an oral ... A range of parameters, including blood glucose and lipid, serum insulin, glucose tolerance, were tested ..... Homeostasis model.

  8. Surface Plasmon Absorption in MoS2 and Graphene-MoS2 Micro-Gratings and the Impact of a Liquid Crystal Substrate (Postprint)

    Science.gov (United States)

    2018-04-27

    was partially supported by EOARD Grant 15IOE011. 1 L. Ju, B. Geng, J. Horng, C. Girit, M. Martin , Z. Hao, H. A. Bechtel, X. Liang, A. Zettl, Y. R... Martin -Moreno, and A. Yu. Nikitin, J. Opt. 15, 114008 (2013). 7 R. Alaee, M. Farhat, C. Rockstuhl, and F. Lederer, Opt. Express 20, 28017 (2012). 8 Y...Chaves, J. D. Caldwell, A. Kumar, N. X. Fang, P. Avouris, T. F. Heinz, F. Guinea, L. Martin -Moreno, and F. Koppens, Nature Materials 16, 182 (2017

  9. [Veterinary medicine comment on camel medicine in Fan-mu tsuan yen-fang].

    Science.gov (United States)

    von den Driesch, A

    1997-01-01

    This short paragraph tries to identify the camel diseases compiled in the old chinese text according to modern veterinary terms. Due to the specific terminology of the camel treatise and its overall scarce symptomatology the diseases are difficult to evaluate. The majority of them obviously deal with acute infectious diseases which manifest themselves under such symptoms as high fever, depression, anorexia, cachexia, diarrhoea, general weakness, etc. But there are some diseases and ailments which can be interpreted in modern terms my means of the symptoms, descriptions and cures, e.g. mange, paradontosis and wry-neck syndrome.

  10. A Plan to Renovate the Tong Fang-Xiang Lane in Suzhou City

    Institute of Scientific and Technical Information of China (English)

    1990-01-01

    <正> With the perception of concept of land value and the improving standards of city management,the traditionalthinking and concept of planning requires innovation.This article presents the investigation planners carried out in the reform of planning concept based on the experi-ences of other countries and with special reference to the situation in China.It is hoped that this would provide op-portunities for further discussions among planners in the country.

  11. X-ray Time Lags in TeV Blazars X. Chen1,∗ , G. Fossati1, E. Liang1 ...

    Indian Academy of Sciences (India)

    Abstract. We use Monte Carlo/Fokker–Planck simulations to study the. X-ray time lags. Our results show that soft lags will be observed as long as the decay of the flare is dominated by radiative cooling, even when acceleration and cooling time scales are similar. Hard lags can be pro- duced in the presence of a competitive ...

  12. Modelacio de sedimentadors en plantes de tractament d'aigues residuals. Aplicacio al proces de fermentacio - elutracio de fangs primaris

    Science.gov (United States)

    Ribes Bertomeu, Josep

    Wastewater treatments require the execution of many conversion processes simultaneously and/or consecutively, making them a tricky object of study. Furthermore, complexity of treatment processes is increasing not only for the more stringent effluent standards required, but also for the new trends towards sustainable development, which in this process are mainly focused on energy saving and nutrient recovery from wastewaters in order to improve their life cycle. For this reason it becomes necessary to use simulation tools which are able to represent all these processes by means of a suitable mathematical model. They can help in determining and predicting the behaviour of the different treatment schemes. These simulators have become essential for the design, control and optimization of wastewater treatment plants (WWTP). Settling processes have a significant role in the accomplishment of effluent standards and the correct operation of the plant. However, many models that are currently employed for WWTP design and simulation do not take into account settling processes or they are handled in a very simple way, by neglecting the biochemical processes that can occur during sedimentation. People of CALAGUA research group have focussed their efforts towards a new philosophy of simulating treatment plants, which is based on the use of a unique model to represent all physical, chemical and biological processes taking place in WWTPs. In this research topic, they have worked on the development of a general quality model that considers biological conversion processes carried out by different microorganism groups, acid base chemical interactions affecting the pH value in the system, and gas-liquid transfer processes. However, a generalized use of such a quality model requires its combination with a flux model, principally for those processes where completely mixture can not be assumed, as for instance, settlers and thickeners in WWTPs. The main objective of this work has been the development and validation of a general settling model that allows simulating the main settling operations taking place in a WWTP, considering both primary and secondary settlers and thickeners. It consists in a one-dimensional model based on the flux theory of Kynch and the double-exponential settling function of Takacs that takes into account flocculation, hindered settling and compression processes. The model has been applied to simulation of settlers and thickeners by means of splitting the system into several horizontal layers, all of them considered as completely mixed reactors which are interconnected by mass flux obtained from the settling model. In order to simulate the conversion processes taking place during sedimentation, the general quality model BNRM1 has been added, and it has been proposed an iterative procedure for solving the equations for each layer in which the settler has been divided. The settling flux model validation, along with the quality model, has been carried out by applying them to a simulation of primary sludge fermentation - elutriation process. This process has been studied on a pilot plant located in the Carraixet WWTP in Alboraia (Valencia). In order to simulate the observed decrease in solids separation efficiency in the studied fermentation - elutriation process, the quality model has been modified with the addition of a new process called "disintegration of complex particulate material". This process influences the settleability of the sludge because it is considered that the disintegrated solids become non-settleable solids. This modification implies the addition of two new kinetic parameters (the specific disintegration velocity for volatile particulate material and the specific disintegration velocity for non volatile particulate material). However, the settling parameter that represents the non-settleable fraction of total suspended solids is eliminated from the model and it has been transformed into an experimental variable which is quite easy to analyze. The result of this modification is a more general model, which is applicable to fermentation - elutriation process working at any operating condition. Finally, the behaviour and capabilities of the developed model have been tested by simulating a complete WWTP on the DESASS simulation software, developed by the research group. This example includes the most important processes that can be used in a WWTP: biological nutrient removal, primary sludge fermentation and sludge digestion. The model allows considering both settling processes and biochemical processes as a whole (denitrification in secondary settlers, primary sludge fermentation and VFA elutriation, phosphorus release in thickeners because of the PAO decay, etc.). The developed model implies an important advance in study of new wastewater treatment processes because it allows dealing with global process optimization problems, by means of full plants simulation. It is very useful for studying the effects of a modification in operation conditions of one element over the operation of the rest of the elements of the WWTP. (Abstract shortened by UMI.).

  13. Buccal venom gland associates with increased of diversification rate in the fang blenny fish Meiacanthus (Blenniidae; Teleostei).

    Science.gov (United States)

    Liu, Shang-Yin Vanson; Frédérich, Bruno; Lavoué, Sébastien; Chang, Jonathan; Erdmann, Mark V; Mahardika, Gusti Ngurah; Barber, Paul H

    2018-08-01

    At the macroevolutionary level, many mechanisms have been proposed to explain explosive species diversification. Among them morphological and/or physiological novelty is considered to have a great impact on the tempo and the mode of diversification. Meiacanthus is a genus of Blenniidae possessing a unique buccal venom gland at the base of an elongated canine tooth. This unusual trait has been hypothesized to aid escape from predation and thus potentially play an important role in their pattern of diversification. Here, we produce the first time-calibrated phylogeny of Blenniidae and we test the impact of two morphological novelties on their diversification, i.e. the presence of swim bladder and buccal venom gland, using various comparative methods. We found an increase in the tempo of lineage diversification at the root of the Meiacanthus clade, associated with the evolution of the buccal venom gland, but not the swim bladder. Neither morphological novelty was associated with the pattern of size disparification in blennies. Our results support the hypothesis that the buccal venom gland has contributed to the explosive diversification of Meiacanthus, but further analyses are needed to fully understand the factors sustaining this burst of speciation. Copyright © 2018 Elsevier Inc. All rights reserved.

  14. Fang and Feather: The Origin of Avian-Serpent Imagery at Teotihuacan and Symbolic Interaction With Jaguar Iconography in Mesoamerica

    OpenAIRE

    Math, Kathryn

    2017-01-01

    The central Mexican city of Teotihuacan rose to prominence in the last century BC and lasted for six hundred years. The civic plan was arranged around two main perpendicular avenues. This north-south axis was lined with temples and public monuments. By the third century AD, population was housed in apartment compounds, all precisely aligned with the overarching grid plan (Manzanilla, 1999). On the walls were murals depicting ornately dressed administrators, armor-clad warriors, and fantastic ...

  15. 專論/專利指標發展研究/阮明淑、梁峻齊(Ming-Shu Yuan, Chun-Chi Liang

    Directory of Open Access Journals (Sweden)

    阮明淑、梁峻齊 Ming-Shu Yuan, Chun-Chi Liang

    2009-10-01

    Full Text Available 有鑑於專利資訊在現今產業發展中扮演重要的角色,專利指標成為度量專利資訊的重要參考。本文整理專利指標的發展演進及其在臺灣地區的相關研究,歸納出專利指標的應用分類與意涵。目前在臺灣地區的專利指標相關應用研究中,可以將專利指標區分為專利一般特性指標、專利引用指標與專利技術指標等,分別描述專利的一般特徵、引用與被引用的情況,以及技術的表現。如此正好呈現專利資訊的本質,若再配合時間與專業領域的因素,並以數量、頻率或複合指標的形式呈現,即可對公司、產業與國家等不同的對象���供適切之參考依據。本研究說明目前專利指標研究的概況,可以作為未來相關專利指標研究發展的基礎,更希望可以提供相關政策制定和產業佈局上專利指標選用之參考。 Because nowadays the patent information plays the important role of the industrial development, the patent indexes become the important reference to evaluate the patent information. This article provides the development of the patent indexes and related researches in Taiwan, and generalizes the application of classification and implication of the patent indexes. Presently the related patent index researches in Taiwan could be distinguished the patent indexes into general characteristic, the quotation and the technology and so on. Such discrimination shows the essence of the patent information and if it can compare with the factors of time and professional fields and presents in the forms of the quantity, frequency or composite indexes, it can provide the appropriate information to the company, the industry or the country. This article not only offers the understanding of the present researches of the patent indexes, but also provides the reference of the policy formulation and the industrial layout. 頁次:88-106

  16. The Analysis of Differences and Similarities of Eastern and Western Women’s Images in Liang Sanbo Yu Zhu Yingtai and Romeo and Juliet Novel

    Directory of Open Access Journals (Sweden)

    Yenny Yenny

    2010-11-01

    Full Text Available Sanpek Engtay and Romeo Juliet are the two famous classic love novels from Eastern and Western countries. They are liked by many generation of eastern and western readers. Both novels describe the image of women at each decade. Engtay represents the image of women at feudalism era while Juliet represents it Renainsance era. In this article, the writer did research at education, marriage, love, women's personality, and women's position at each decade. Library research was done in this study with the purpose of letting people know the differences and similarities of women's images between those two decades It can be concluded that in both writings, they have some similarities when describing love, mindset, and women's personality. The differences are about education, marriage, and women's position at feudalism and Renainsance decades.

  17. 论陈亮事功主义伦理思想的基本特征%On Chen Liang's Essential Features of Utilitarian Ethics

    Institute of Scientific and Technical Information of China (English)

    朱晓鹏

    2005-01-01

    陈亮是永康学派的创始人.他的事功主义伦理思想的基本特征是"理欲统一"的道德观、"义利合一"的价值观和"学为成人"的人生观.这种事功主义伦理思想具有创新精神,对中国传统的伦理观是一种挑战,对后世产生了深远的影响.

  18. Nanoparticles prepared from the water extract of Gusuibu (Drynaria fortunei J. Sm. protects osteoblasts against insults and promotes cell maturation

    Directory of Open Access Journals (Sweden)

    Hsu C-K

    2011-07-01

    Full Text Available Chung-King Hsu1,2, Mei-Hsiu Liao3, Yu-Tyng Tai4, Shing-Hwa Liu5, Keng-Liang Ou6, Hsu-Wei Fang7, I-Jung Lee8, Ruei-Ming Chen2,31Institute of Materials Science and Engineering, National Taipei University of Technology, 2Cell Physiology and Molecular Image Research Center, Taipei Medical University-Wan Fang Medical Center, 3Graduate Institute of Medical Sciences, Taipei Medical University, 4Department of Anesthesiology, Taipei Medical University-Wan Fang Medical Center, 5Institute of Toxicology, College of Medicine, National Taiwan University, 6Graduate Institute of Biomedical Materials and Engineering, Taipei Medical University, 7Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, 8Division of Information and Herbarium, National Research Institute of Chinese Medicine, Taipei, TaiwanAbstract: Our previous study showed that Gusuibu (Drynaria fortunei J. Sm. can stimulate osteoblast maturation. This study was further designed to evaluate the effects of nanoparticles prepared from the water extract of Gusuibu (WEG on osteoblast survival and maturation. Primary osteoblasts were exposed to 1, 10, 100, and 1000 µg/mL nanoparticles of WEG (nWEG for 24, 48, and 72 hours did not affect morphologies, viability, or apoptosis of osteoblasts. In comparison, treatment of osteoblasts with 1000 µg/mL WEG for 72 hours decreased cell viability and induced DNA fragmentation and cell apoptosis. nWEG had better antioxidant bioactivity in protecting osteoblasts from oxidative and nitrosative stress-induced apoptosis than WEG. In addition, nWEG stimulated greater osteoblast maturation than did WEG. Therefore, this study shows that WEG nanoparticles are safer to primary osteoblasts than are normal-sized products, and may promote better bone healing by protecting osteoblasts from apoptotic insults, and by promoting osteogenic maturation.Keywords: Gusuibu, nanoparticles, cell protection, osteoblast maturation

  19. A Chinese medicine warm compress (Wen Jing Zhi Tong Fang), combined with WHO 3-step analgesic ladder treatment for cancer pain relief: A comparative randomized trial.

    Science.gov (United States)

    Cai, Peiling; Li, Liuning; Hong, Hongxi; Zhang, Liwen; He, Chunxia; Chai, Xiaoshu; Liu, Bai; Chen, Zhijian

    2018-03-01

    This study aimed to assess the effectiveness of Chinese medicine warm compress (CMWC) on back meridians in relieving cancer pain, reducing adjuvant analgesic doses and adverse reactions, and improving the quality of life (QOL). A total of 62 patients (age range 39-82 years) diagnosed with a malignant tumor and suffering from cancer-related pain were randomly divided into a treatment group (group A) and a control group (group B) (n = 31 for each). The patients in both groups were administered appropriate drugs for 2 cycles of 7-day treatments according to the World Health Organization (WHO) 3-step ladder for cancer pain relief in adults. In addition, a CMWC was given to patients in group A. Pain relief was assessed using the visual analogue scale (VAS) at various time points before and after interventions in each group. Alteration of analgesic doses, adverse reactions, performance status (PS), and QOL were evaluated and any differences between groups A and B evaluated. VAS scores at various time points after treatment were significantly decreased compared with the baseline level in group A. Overall response rate was significantly improved in group A compared with group B (70.97% vs 29.03%, P pain relief efficacy in various locations were found in group A after treatment vs before treatment (P pain with reduced doses, less adverse reactions, and improved QOL.

  20. Feng xian tai du yu jiao yu he zhi ye xuan ze xing wei: yi ge shi yan fang fa de yan jiu an li

    NARCIS (Netherlands)

    Ding, X.; Sun, Y.; Hartog, J.

    2009-01-01

    An experimental study on risk attitude and choice behavior of education and career This paper introduces a research on risk attitude and choice behavior of education and career. Using the experimental methods, this study focuses on testing the reliability and validity of risk attitude measurement.

  1. [Comparison of Curative Effect between Fu Fang Huang Dai Pian and Arsenic Trioxide in Treatment of 45 Patients with Acute Promyelocytic Leukaemia].

    Science.gov (United States)

    Wang, Jian; Huang, Jun-Bin; Liu, Zu-Lin; Zhang, Bi-Hong; Xu, Hong-Gui; Xue, Hong-Man; Chen, Chun

    2017-12-01

    To investigate the clinical efficacy of Fu Fan Huang Dai Pian(RIF) and arsenic trioxide (ATO) regimens for treatment of children with acute promyelocytic leukemia (APL) and to explore the risk factors affecting the prognosis of patients. The clinical data of 45 newly diagnosed APL children admitted in our hospital from January 2004 to May 2017 were analyzed retrospectively. Among 45 APL children, 25 children were treated by chemotherapetic regimen including RIF (RIF group), another 20 children were treated by chemotherapeutic regimen including ATO (ATO group). The follow-up was performed in all APL children. The prognosis and incidence of side reactions from drugs in 2 groups were compared, and the high risk factors affecting the prognosis of patients were analyzed. The median follow-up time was 49.8% months. In RIF group, no early death occured in 25 APL children; 5 cases did not achieve complete remission (CR) after induction therapy, CR rate was 88%. Out of 25 cases 2 caes relapsed, 3 cases died, 20 cases maintained contined CR (CCR), 2 cases failed to be followed-up. In ATO group, 2 cases suffered from early death, 5 cases did not achieve CR after induction therapy, CR rate was 90%, 2 caese relapsed and died, 15 cases maintained CCR, the follow-up failed in 1 caes. The 5 year- OS and EFS rate in all the patients were predicted as (82.2±6.2)% and (76.4±6.6)% respectively. The OS and EFS rate in RIF group were (86.1±7.4)% and (78.4±8.6)% respectively, which were significantly different from OS and EFS rate (76.4%±10.6%) and (74.0%±10.1%) respectively in ATO group (all P>0.05). As for the side reaction from drug, except for the cardiac damage (P0.05). In addition, the 5 year-OS and EFS rates in APL children with CNSL were significantly lower than those in APL children without CNSL (all Phigh risk were significantly lower than those in APL children reached M1 after induction therapy and with low and standerd risk (Ptreatment of APL children. The CNSL, poor respond to treatment, high risk in clinical stratification are high risk factors affecting prognosis of patients.

  2. Influence of environmental factors on mineral elements transport and accumulation in leaves and fruits of kiwifruit plants [Actinidia deliciosa (A.Chev.) C.F.Liang et A.R.Ferguson; Basilicata

    International Nuclear Information System (INIS)

    Montanaro, G.; Dichio, B.; Palese, A.M.

    2006-01-01

    In this study, the effect of light availability on actinidia leaf and fruit N, P, K, Ca and Mg accumulation is reported. At fruit-set, exposed and shaded treatments were imposed. Fruit and leaf transpiration was measured using a portable gas exchanges analyser (ADC-LCA4). Sap flow was monitored on whole canes using the Dynagage Sap-Flow (heat balance method). Transpiration of exposed leaves was on average 66% higher than the one of shaded leaves. Sap flow of exposed canes was on average 53 g mE-2 per day; the shadow treatment determined a 60% decrease of sap flow. These differences affected the accumulation of those minerals, notably calcium, which are transported mainly via xylem. Fruit calcium content reached approximately 40 mg fruitE-1 in exposed fruits, while in the shaded ones it was 23 mg fruitE-1. Our results suggest that a greater light availability can promote calcium accumulation. Therefore, the accurate training system management, favouring light interception by canopy and fruits, could be a tool for fruit quality improvement [it

  3. Protective effect of (-)-epigallocatechin gallate on ultraviolet b ...

    African Journals Online (AJOL)

    Chang Liu1, Xin-Qiang Zheng1, Li-Ping Xiang2, Jian-Liang Lu1, Curt ..... Fukunagam M, Tsuru K, Horikawa T. UV-induced skin ... Liang YR, Kang SY, Deng L, Xiang LP, Zheng XQ. ... Lee XZ, Liang YR, Chen H, Lu JL, Liang HL, Huang FP,.

  4. Clinicopathological and prognostic significance of OCT4 in patients with hepatocellular carcinoma: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Liang CJ

    2017-12-01

    Full Text Available Chaojie Liang,* Yingchen Xu,* Hua Ge, Guangming Li, Jixiang Wu Department of General Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China *These authors contributed equally to this work Background and aims: Octamer-binding transcription factor 4 (OCT4 has been implicated in the development of hepatocellular carcinoma (HCC, although the findings are controversial. We conducted a meta-analysis to assess the correlation between OCT4 and the clinicopathological characteristics and the prognostic value in HCC.Methods: An electronic search for relevant articles was conducted in PubMed, Cochrane Library, Web of Science, EMBASE database, Chinese CNKI, and Chinese WanFang database. Correlations between OCT4 expression and clinicopathological features and survival outcomes were analyzed. Pooled odds ratios and hazard ratios with 95% CIs were calculated using STATA 14.2 software.Results: A total of 10 trials with 985 patients were included. Positive OCT4 expression was correlated with tumor size, tumor numbers, differentiation, and TNM stage. OCT4 expression was not correlated with gender, age, hepatitis B surface antigen, alfa-fetoprotein, liver cirrhosis, vascular invasion, or tumor encapsulation. OCT4 expression was associated with poor 3- and 5-year overall survival, and disease-free survival rate.Conclusion: OCT4 expression was associated with tumor size, tumor numbers, differentiation, and TNM stage in HCC. OCT4 may be a useful prognostic biomarker for HCC. Keywords: octamer-binding transcription factor 4, hepatocellular carcinoma, prognosis, meta-analysis

  5. Design, synthesis, and structure–activity relationships of 2-benzylidene-1-indanone derivatives as anti-inflammatory agents for treatment of acute lung injury

    Directory of Open Access Journals (Sweden)

    Xiao S

    2018-04-01

    Full Text Available Siyang Xiao,1,* Wenxin Zhang,1,* Hongjin Chen,1 Bo Fang,1 Yinda Qiu,2 Xianxin Chen,1 Lingfeng Chen,1 Sheng Shu,1 Yunjie Zhao,1 Zhiguo Liu,1 Guang Liang1 1Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China; 2College of Life and Environmental Science, Wenzhou University, Wenzhou, Zhejiang, China *These authors contributed equally to this work Purpose: The purpose of this study was to design and synthesize novel 2-benzylidene-1-indanone derivatives for treatment of acute lung injury. Methods: A series of 39 novel 2-benzylidene-indanone structural derivatives were synthesized and evaluated for anti-inflammatory activity in lipopolysaccharide (LPS-stimulated murine primary macrophages. Results: Most of the obtained compounds effectively inhibited the LPS-induced expression of IL-6 and TNF-α. The most active compound, 8f, was found to significantly reduce LPS-induced pulmonary inflammation, as reflected by reductions in the concentration of total protein, inflammatory cell count, as well as the lung wet/dry ratio in bronchoalveolar lavage (BAL fluid. Furthermore, 8f effectively inhibited mRNA expression of several inflammatory cytokines after LPS challenge in vitro and in vivo. Administration of 8f also blocked LPS-induced activation of the proinflammatory NF-κB/MAPK signaling pathway. Conclusion: The simple synthetic preparation and biological properties of these derivatives make these 2-benzylidene-indanone scaffolds promising new entities for the development of anti-inflammatory therapeutics for the treatment of acute lung injury. Keywords: indanone, acute lung injury, drug design, anti-inflammation, synthesis

  6. Turbulent Flame Stabilization Methods Using Confinement, Diluents, and High-Potential Electric Fields

    Science.gov (United States)

    2014-08-03

    Kevin Lyons Alexei Saveliev Committee Chair ________________________________ ________________________________ Tiegang Fang...Lyons, for his guidance and support -Dr. Alexei Saveliev , Dr. Tiegang Fang, and Dr. Stephen Terry for serving on my committee -Dr. Glenn Walker

  7. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Fang Dong1 Jiang Chenning1 Zhu Ting1 Yang Jinming1. Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Yancheng Teachers University, 50 Kai Fang Da Dao, Yancheng 224002, Jiangsu, P. R. China ...

  8. 專論/以關鍵詞網絡探討動態性知識管理議題/陳良駒;張正宏 | Exploring Dynamic Knowledge Management Research Issues: A Keyword Network Analysis / Liang-Chu Chen; Jeng-Horng Chang

    Directory of Open Access Journals (Sweden)

    陳良駒、張正宏

    2007-10-01

    Full Text Available

    知識管理是企業邁向知識經濟時代的實務顯學,也是學術界近年來持續探討的重要研究議題。然而知識管理的面向是一種多維度的呈現,如何快速而正確的瞭 解知識管理議題的發展,是許多組織知識工作者及學術研究學者努力的目標。許多學者提出知識管理內容的架構及分類,但卻都是屬於一種由上而下的靜態設計。社 會網絡分析是呈現及量測網絡實體成員互動的技術,適合建構關係網絡的動態性。本文嘗試以關鍵詞網絡來分析國內資訊相關系所從事知識管理研究的主題及脈絡, 並透過關鍵詞的連結來建構一套動態性的知識管理研究範疇。研究成果除驗證知識管理學域中的研究重點,更透過網絡關係來連結多樣性的研究構想,進而提供產官 學界更宏觀且動態的知識管理研究建議。

    Knowledge management (KM is an important practice in a corporation and an essential issue that academic scholars intend to explore continuously in the era of knowledge economy. However, KM presents a variety of perspectives that are still undefined for many knowledge workers and academic researchers. Many scholars propose a few categories and frameworks about KM, but a static outcome. Social network analysis (SNA is a method to present and measure the interaction among network entities and it is suitable to construct the dynamic relationship networks. The purpose of this study is to acquire the research issues and contexts of KM within information-related graduate schools based on a keyword network analysis. Moreover, we build a dynamic KM research network through these linkages with keywords. The results of this study confirm the essential research perspectives in a KM domain and suggest a variety of KM research ideas which provide the industries, governments, and academic communities with a macro and dynamic KM research viewpoint.

    頁次:81-94

  9. The application of thick translation method of puns in the translated version of works of William Shakespeare by Liang Shiqiu%双关语的"厚重翻译法"应用——以梁实秋的《莎士比亚全集》翻译为例

    Institute of Scientific and Technical Information of China (English)

    李明

    2010-01-01

    作为我国著名的文学家、翻译家,梁实秋在的翻译中,采用了厚重翻译法,即译文加注的方法.其中对于双关语的翻译更是炉火纯青,为学术界所称道,使之翻译的成为莎氏学术研究的杰作.

  10. Retraction. Linger RMA, DeRyckere D, Brandao L, Sawczyn KK, Jacobsen KM, Liang X, Keating AK, Graham DK. Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia. Blood. 2009;114(13):2678-2687.

    Science.gov (United States)

    2012-08-16

    The authors retract the 24 September 2009 article cited above, prepublished on 30 July 2009. They have recently learned that some of the cell lines used in their paper were inadvertently misidentified. Although the parental 697 and REH cell lines used to generate the Mer knockdown lines were authenticated by short tandem repeat (STR) analysis before publication, the transduced progeny were not analyzed until recently. The results of STR analysis indicate that the 697 shMer1A and 697 shMer1B cell lines are actually derived from the REH parental cell line. Importantly, the identities of the other 6 REH and 697 cell lines published in this study have been verified as authentic.Since this unfortunate discovery, the authors have generated new 697 Mer knockdown cell lines and authenticated their identity. These new cell lines are being used to replicate the original work. Data obtained to date support the overall findings and conclusions of the original report; these data will be described in a new manuscript. The authors sincerely apologize to the readers, reviewers, and editors of Blood for making this honest mistake.

  11. Lower expressed miR-198 and its potential targets in hepatocellular carcinoma: a clinicopathological and in silico study

    Directory of Open Access Journals (Sweden)

    Huang WT

    2016-08-01

    Full Text Available Wen-Ting Huang,1,* Han-Lin Wang,1,* Hong Yang,2 Fang-Hui Ren,1 Yi-Huan Luo,1 Chun-Qin Huang,1 Yue-Ya Liang,1 Hai-Wei Liang,1 Gang Chen,1 Yi-Wu Dang1 1Department of Pathology, 2Department of Ultrasonography, First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China *These authors contributed equally to this work Purpose: To investigate the clinicopathological value and potential roles of microRNA-198 (miR-198 in hepatocellular carcinoma (HCC.Methods: Ninety-five formalin-fixed paraffin-embedded HCC and the para-cancerous liver tissues were gathered. Real-time reverse transcription quantitative polymerase chain reaction was applied to determine the miR-198 expression. The association between the miR-198 expression and clinicopathological features was examined. Meanwhile, potential target messenger RNAs of miR-198 in HCC were obtained from 14 miRNA prediction databases and natural language processing method, in which we pooled the genes related to the tumorigenesis and progression of HCC and classified them by their frequency. The selected target genes were finally analyzed in the Gene Ontology analysis and Kyoto Encyclopedia of Genes and Genomes pathway.Results: miR-198 expression was significantly lower in HCC than that in adjacent noncancerous liver tissues (1.30±0.72 vs 2.01±0.58, P<0.001. Low miR-198 expression was also correlated to hepatitis C virus infection (r=-0.48, P<0.001, tumor capsular infiltration (r=-0.43, P<0.001, metastasis (r=-0.26, P<0.010, number of tumor nodes (r=-0.25, P=0.013, vaso-invasion (r=-0.24, P=0.017, and clinical tumor node metastasis stage (r=-0.23, P=0.024. Altogether, 1,048 genes were achieved by the concurrent prediction from at least four databases and natural language processing indicated 1,800 genes for HCC. Further, 127 overlapping targets were further proceeded with for pathway analysis. The most enriched Gene Ontology terms in the potential target messenger RNAs of mi

  12. A family-oriented treatment program for youths with ketamine abuse and their caregivers: a pilot study in Taiwan

    Directory of Open Access Journals (Sweden)

    Wang LJ

    2015-07-01

    Full Text Available Liang-Jen Wang,1 Shing-Fang Lu,1 Wen-Jiun Chou,1 Mian-Yoon Chong,2 Yao-Hsing Wang,1 Yu-Lian Hsieh,1 Yi-Hsuan Lee,1 Ching Chen2 1Department of Child and Adolescent Psychiatry, 2Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan Objective: The abuse of ketamine by youths has grown into a serious public health issue. However, a reliable and efficient treatment has still not been found for youths who abuse ketamine. This pilot study investigated the effects of a family-oriented treatment program for ketamine-using youths and their caregivers.Methods: To carry out this study, 42 youths with ketamine use (mean age 16.6±1.1 years who were referred to take part in a 10-week treatment program based on motivational enhancement principles were selected, as were their principal caregivers (mean age 46.4±7.1 years, who were similarly referred to take part in a 10-week training program for parenting skills. The study had the youths complete the Chinese Craving Beliefs Questionnaire, the Adolescents’ Behavior problem Scale, and the Family APGAR both immediately before and after the program. Likewise, the youths’ caregivers completed the Family APGAR, the 12-item version of the Chinese Health Questionnaire, and the Parenting Stress Index.Results: Of the 42 youth–caregiver pairs that took part in this study, 37 (88% completed the 10-week program and both sets of assessments. After the treatment, the participating youths’ substance cravings declined (t=3.88, P<0.001, while family function, as perceived by the participating caregivers, significantly increased (t=2.22, P=0.033. The improvement in caregivers’ perceptions of family function were positively related to the improvement of the caregivers’ health status (r=-0.36, P=0.022.Conclusion: According to its results, this pilot study submits that family-oriented treatment programs may be considered a potentially effective

  13. Screening of potential diagnostic markers and therapeutic targets against colorectal cancer

    Directory of Open Access Journals (Sweden)

    Tian XQ

    2015-07-01

    Full Text Available XiaoQing Tian, DanFeng Sun, ShuLiang Zhao, Hua Xiong, JingYuan Fang Department of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Institute of Digestive Disease, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Objective: To identify genes with aberrant promoter methylation for developing novel diagnostic markers and therapeutic targets against primary colorectal cancer (CRC. Methods: Two paired CRC and adjacent normal tissues were collected from two CRC patients. A Resi: MBD2b protein-sepharose-4B column was used to enrich the methylated DNA fragments. Difference in the average methylation level of each DNA methylation region between the tumor and control samples was determined by log2 fold change (FC in each patient to screen the differentially methylated DNA regions. Genes with log2FC value ≥4 or ≤-4 were identified to be hypermethylated and hypomethylated, respectively. Then, the underlying functions of methylated genes were speculated by Gene Ontology database and pathway enrichment analyses. Furthermore, a protein–protein interaction network was built using Search Tool for the Retrieval of Interacting Genes/Proteins database, and the transcription factor binding sites were screened via the Encyclopedia of DNA Elements (ENCODE database. Results: Totally, 2,284 and 1,142 genes were predicted to have aberrant promoter hypermethylation or hypomethylation, respectively. MAP3K5, MAP3K8, MAPK14, and MAPK9 with promoter hypermethylation functioned via MAPK signaling pathway, focal adhesion, or Wnt signaling pathway, whereas MAP2K1, MAPK3, MAPK11, and MAPK7 with promoter hypomethylation functioned via TGF-beta signaling pathway, neurotrophin signaling pathway, and chemokine signaling pathway. CREBBP, PIK3R1, MAPK14, APP, ESR1, MAPK3, and HRAS were the seven hubs in the constructed protein–protein interaction network. RPL22, RPL36, RPLP2, RPS7, and RPS9 were commonly regulated by

  14. Consolidation chemotherapy improves progression-free survival in stage III small-cell lung cancer following concurrent chemoradiotherapy: a retrospective study

    Directory of Open Access Journals (Sweden)

    Chen XR

    2016-09-01

    Full Text Available Xin-Ru Chen,1,* Jian-Zhong Liang,2,* Shu-Xiang Ma,1 Wen-Feng Fang,1 Ning-Ning Zhou,1 Hai Liao,1 De-Lan Li,1 Li-Kun Chen1 1Department of Medical Oncology, 2Department of Pathology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China *These authors contributed equally to this work Background: Concurrent chemoradiotherapy (CCRT is the standard treatment for limited-stage small-cell lung cancer (LD-SCLC. However, the efficacy of consolidation chemotherapy (CCT in LD-SCLC remains controversial despite several studies that were performed in the early years of CCT use. The aim of this study was to reevaluate the effectiveness and toxicities associated with CCT. Methods: This retrospective analysis evaluated 177 patients with stage IIIA and IIIB small-cell lung cancer (SCLC who underwent CCRT from January 2001 to December 2013 at Sun Yat-Sen University Cancer Center (SYSUCC. Overall survival (OS and progression-free survival (PFS were analyzed using Kaplan–Meier methods. Univariate and multivariate analyses were performed to analyze patient prognosis factors. Results: Among the 177 patients, 72 (41% received CCT and 105 (59% did not receive CCT. PFS was significantly better for patients in the CCT group compared to that for patients in the non-CCT group (median PFS: 17.0 vs 12.9 months, respectively, P=0.031, whereas the differences in OS were not statistically significant (median OS: 31.6 vs 24.8 months, respectively, P=0.118. The 3- and 5-year OS rates were 33.3% and 20.8% for patients in the CCT group and 27.6% and 6.7% for patients in the non-CCT group, respectively. Multivariate analysis revealed that having a pretreatment carcinoembryonic antigen level <5 ng/mL (P=0.035, having undergone prophylactic cranial irradiation (P<0.001, and having received CCT (P=0.002 could serve as favorable independent prognostic factors

  15. Traumatic osteoarthritis-induced persistent mechanical hyperalgesia in a rat model of anterior cruciate ligament transection plus a medial meniscectomy

    Directory of Open Access Journals (Sweden)

    Tsai HC

    2017-12-01

    Full Text Available Hsiao-Chien Tsai,1–3 Ta-Liang Chen,2–4 Yu-Pin Chen,5 Ruei-Ming Chen1,3,6 1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan; 2Department of Anesthesiology, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan; 3Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 4Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan; 5Department of Orthopedic Surgery, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; 6Comprehensive Cancer Center, Taipei Medical University, Taipei, Taiwan Background: Osteoarthritis (OA is a degenerative joint disease characterized by progressive cartilage degeneration, subchondral bone changes, osteophyte formation, and synovitis. A major symptom is pain that is triggered by peripheral and central changes within the pain pathways. Some surgery-induced joint instability rat models of OA were described to mimic traumatic OA. Several behavioral tests were developed to access OA-induced pain. However, follow-up in most studies usually only occurred for about 4 weeks. Since traumatic OA is a chronic disease which gradually develops after trauma, the pattern of pain might differ between early and late stages after the trauma. Purpose: To observe the time-dependent development of hypersensitivity after traumatic OA and to determine the best timing and methods to investigate traumatic OA-induced pain.Methods: Anterior cruciate ligament transection plus medial meniscectomy was used to induce traumatic OA in Sprague-Dawley rats. Traumatic OA-induced pain was evaluated using four different behavioral tests for 15 weeks.Results: A significant difference in mechanical hypersensitivity developed throughout the observational period. It was worst in the first 3 weeks after the operation, then became less significant

  16. Metformin inhibits proliferation and cytotoxicity and induces apoptosis via AMPK pathway in CD19-chimeric antigen receptor-modified T cells

    Directory of Open Access Journals (Sweden)

    Mu Q

    2018-04-01

    Full Text Available Qian Mu,1,2,* Miao Jiang,1,* Yuzhu Zhang,1 Fei Wu,1 Hui Li,1 Wen Zhang,1 Fang Wang,1 Jiang Liu,1 Liang Li,1 Dongshan Wang,3 Wenjuan Wang,1 Shiwu Li,1 Haibo Song,4 Dongqi Tang1 1Gene and Immunotherapy Center, The Second Hospital of Shandong University, Jinan, People’s Republic of China; 2Department of Endocrinology and Metabolism, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Health Management Center, The Second Hospital of Shandong University, Jinan, People’s Republic of China; 4Central Research Laboratory, Zibo Maternal and Child Health Hospital, Affiliated to Shandong Academy of Medical Science, Zibo, People’s Republic of China *These authors contributed equally to this work Background: CD19-chimericantigen receptor (CAR modified T cells (CD19-CAR T cells have been well documented to possess potent anti-tumor properties against CD19-expressingleukemia cells. As a traditional medicine, metformin has been widely used to treat type II diabetes mellitus and more recently has become a candidate for the treatment of cancer. However, no report has revealed the direct effect of metformin on CD19-CAR T cell biological function and its underling mechanisms. Purpose: The purpose of this research was to explore the effect of metformin on CD19-CAR T cell biological function and the mechanisms involved. Methods: CD19-CAR T cells proliferation, apoptosis and cytotoxicity were mainly tested by CCK-8 assay, flow cytometry and ELISA. The detection of mechanism primarily used western blot. Bioluminescence imaging is the main application technology of animal studies. Results: In the current study, it was found that metformin inhibited CD19-CAR T cell proliferation and cytotoxicity and induced apoptosis. Furthermore, our study revealed that metformin activated AMPK and suppressed mTOR and HIF1α expression. By using an AMPK inhibitor, compound C, we demonstrated the crucial roles of AMPK in CD19

  17. Reply to the comment by Q.Q. Qiao et al. on ;Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression; by Tao Zhang, Xiaomin Fang, Chunhui Song, Erwin Appel, and Yadong Wang [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044

    Science.gov (United States)

    Zhang, Tao; Fang, Xiaomin; Song, Chunhui; Appel, Erwin; Wang, Yadong

    2017-07-01

    Qiao et al. (2016) commented on our work (Zhang et al., 2014) and rejected our reinterpretation of the magnetostratigraphic results of Huang et al. (2006) and Li et al. (2006), with the results gained using the Dynamic Time Warping Algorithm technique (DTWAT) as their main basis. However, Qiao et al. (2016) did not provide details of their modeling inputs, and, in particular, the parameters they chose for their calculations, where such parameters can have a serious impact upon any results. We therefore performed calculations using the same software (i.e., Qupydon) as Qiao et al. (2016), using reliable parameter settings. The results showed that the ;interesting correlation; of a 6000 minimum cost output completely correlate with the magnetostratigraphic Chrons C18r to C3An.1n ( 40-6 Ma), which is consistent with our reinterpreted magnetostratigraphic results. Furthermore, we summarized previous biostratigraphic studies of nearby areas; the data resulting from this process also supported our reinterpreted magnetostratigraphic correlation. We were therefore able to confirm the revised magnetostratigraphic correlation of Zhang et al. (2014).

  18. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. LIANG WANG. Articles written in Journal of Genetics. Volume 92 Issue 3 December 2013 pp 395-402 Research Article. Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction · Ke-Sheng Wang Liang Wang Xuefeng Liu Min Zeng.

  19. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Hui Liang. Articles written in Sadhana. Volume 36 Issue 5 October 2011 pp 885-915. Current trends in multilingual speech processing · Hervé Bourlard John Dines Mathew Magimai-Doss Philip N Garner David Imseng Petr Motlicek Hui Liang Lakshmi Saheer Fabio Valente · More Details Abstract ...

  20. X-ray Radiation Mechanisms and the Beaming Effect of Hot Spots ...

    Indian Academy of Sciences (India)

    Astr. (2011) 32, 193–196 c Indian Academy of Sciences. X-ray Radiation Mechanisms and the Beaming Effect of Hot Spots and Knots in AGN Jets. Jin Zhang1,∗. , Jin-Ming Bai2, Liang Chen2 & Enwei Liang3. 1College of Physics and Electronic Engineering, Guangxi Teachers Education University,. Nanning 530001, China.

  1. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 90; Online resources. Genotyping of the k-casein and -lactoglobulin genes in Chinese Holstein, Jersey and water buffalo by PCR-RFLP. Da-Xi Ren Shu-Ying Miao You-Liang Chen Cai-Xia Zou Xian-Wei Liang Jian-Xin Liu. Volume 90 Online resources 2011 pp e1-e5 ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Chen Fang. Articles written in Journal of Biosciences. Volume 30 Issue 3 June 2005 pp 351-357 Articles. Expression of a ribosome inactivating protein (curcin 2) in Jatropha curcas is induced by stress · Wei Qin Huang Ming-Xing Xu Ying Zhang Xin-Shen Chen Fang · More Details ...

  3. African Journal of Biotechnology - Vol 12, No 49 (2013)

    African Journals Online (AJOL)

    Cloning of a vacuolar H-pryophosphatase gene from emphemeral plant Olimarabidopsis pumila whose overexpression improve salt tolerance in tobacco · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Fang Xu, Yunxia Zhao, Fang Wang, Danli Guo, Yanling Wei, ...

  4. Synthesis and microwave dielectric properties of Ca substituted ...

    Indian Academy of Sciences (India)

    Administrator

    sintered samples were crushed into fine powders. Phase analyses of the .... at the A-site of the perovskite structure decreases, the lattice strain decreases ... Fang L, Men S S, Zhang H, Liu Q and Liu H F 2008 J. Electro- ceram. 21 137. Fang L ...

  5. Life or death? A Physiogenomic Approach to Understand Individual Variation in Responses to Hemorrhagic Shock

    Science.gov (United States)

    2011-01-01

    2009, 234, 1503-1510. [34] Fang, J. F.; Shih, L. Y.; Yuan, K. C.; Fang, K. Y.; Hwang, T. L.; Hsieh, S. Y. Proteomic analysis of post-hemorrhagic...resistant and susceptible barley lines during interaction with the powdery mildew fungus . Plant Mol. Biol., 2001, 47, 739-748. [96] Harris, N. S

  6. Two-Dimensional Fourier Cosine Series Expansion Method for Pricing Financial Options

    NARCIS (Netherlands)

    Ruijter, M.J.; Oosterlee, C.W.

    2012-01-01

    The COS method for pricing European and Bermudan options with one underlying asset was developed in [F. Fang and C. W. Oosterlee, SIAM J. Sci. Comput., 31 (2008), pp. 826--848] and [F. Fang and C. W. Oosterlee, Numer. Math., 114 (2009), pp. 27--62]. In this paper, we extend the method to higher

  7. Journal of Genetics Online Resources

    Indian Academy of Sciences (India)

    /90/e25.pdf. Li H., Liang Y., Sui L., Gao X. and He C. 2011 Characterization of 10 polymorphic microsatellite markers for Mediterranean blue mussel Mytilus galloprovincialis by EST database mining and cross-species amplification. J. Genet.

  8. Genetics Home Reference: ankylosing spondylitis

    Science.gov (United States)

    ... Helmick CG, Felson DT, Lawrence RC, Gabriel S, Hirsch R, Kwoh CK, Liang MH, Kremers HM, Mayes MD, Merkel PA, Pillemer SR, Reveille JD, Stone JH; National Arthritis Data Workgroup. Estimates of the ...

  9. Guiyang_PM2.5_speciation_data_DOI_10.1007/s11631-017-0248-1

    Data.gov (United States)

    U.S. Environmental Protection Agency — ED-XRF inorganic speciation of PM2.5 in Guiyang, China. This dataset is associated with the following publication: Liang, L., N. Liu, M. Landis, X. Xu, X. Feng, Z....

  10. African Journal of Biotechnology - Vol 11, No 69 (2012)

    African Journals Online (AJOL)

    In silico comparative analysis of EST-SSRs in three cotton genomes · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Daojun Yuan, Shaoguang Liang, Zhongxu Lin, Xianlong Zhang, 13269-13371 ...

  11. Trajectory averaging for stochastic approximation MCMC algorithms

    KAUST Repository

    Liang, Faming

    2010-01-01

    to the stochastic approximation Monte Carlo algorithm [Liang, Liu and Carroll J. Amer. Statist. Assoc. 102 (2007) 305-320]. The application of the trajectory averaging estimator to other stochastic approximationMCMC algorithms, for example, a stochastic

  12. Fulltext PDF

    Indian Academy of Sciences (India)

    2013-02-10

    Feb 10, 2013 ... are the most important properties of flavonoids (Winkel-. Shirley 2002 ... available silicon in soils and sediments (Liang et al. 2007;. Schaller et .... An P and Tsuji. W 2008 Growth and nutrient use in four grasses under drought.

  13. (H5N1) strain neuraminidase expressed in yeast Pichia pastoris

    Indian Academy of Sciences (India)

    2014-03-20

    Mar 20, 2014 ... situation, in which production time matters greatly. ... avian influenza, these vaccine manufacturing methods may .... following the manufacturer's guidelines. ..... J, Liang X and Varadarajan R 2010 Design of an HA2-based.

  14. Translational selection in human: More pronounced in housekeeping genes

    KAUST Repository

    Ma, Lina; Cui, Peng; Zhu, Jiang; Zhang, Zhihua; Zhang, Zhang

    2014-01-01

    by Yuan Yuan, Baylor College of Medicine; Han Liang, University of Texas MD Anderson Cancer Center (nominated by Dr Laura Landweber) Eugene Koonin, NCBI, NLM, NIH, United States of America Sandor Pongor, International Centre for Genetic Engineering

  15. Disease: H00801 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Z, Cai B, Hostetler EM, Moran R, Liang D, Estrera A, Safi HJ, Leal SM, Bamshad MJ, Shendure J, Nickerson DA,... ... AUTHORS ... Guo DC, Regalado ES, Gong L, Duan X, Santos-Cortez RL, Arnaud P, Ren

  16. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YOU-LIANG ZHENG. Articles written in Journal of Genetics. Volume 92 Issue 1 April 2013 pp 151-154 Research Note. Identification of 40k -secalin genes · Peng-Fei Qi Qing Chen Thérèse Ouellet Cheng-Xing Le Jia Ai Yu-Ming Wei Ji-Rui Wang You-Liang Zheng · More Details Fulltext ...

  17. New Competition; Foreign Direct Investment and Industrial Development in China

    OpenAIRE

    Liang, G.

    2004-01-01

    textabstractGuoyong Liang is completing his Ph.D. in international business and works at the Rotterdam School of Management, Erasmus University. His current research interests include the theory of the multinational enterprise, business strategy, and business/government interaction. Before his Ph.D. study in the Netherlands, Guoyong Liang was a lecturer at the Shanghai University of Finance and Economics. He was also a fellow at Shanghai Securities and Futures Institute. He has managerial exp...

  18. Temperature hysteretic effect and its influence on colossal ...

    Indian Academy of Sciences (India)

    Financial support from IUC-DAEF, Mumbai, India is greatly appreciated. References. [1] G H Rao, J R Sun, J K Liang, W Y Zhou and X R Cheng, Appl. Phys. Lett. 69, 424 (1996). [2] J R Sun, G H Rao, J K Liang and W Y Zhou, Appl. Phys. Lett. 69, 3924 (1996). [3] J Baszynski, J Kovac, A Kowalczyk, J. Magn. Magn. Mater. 195 ...

  19. Polarizing Ytterbium-Doped all-Solid Photonic Bandgap Fiber with 1150 micrometers2 Effective Mode Area

    Science.gov (United States)

    2015-02-11

    RESPONSIBLE PERSON 19b. TELEPHONE NUMBER Liang Dong Fanting Kong,, Guancheng Gu,, Thomas W. Hawkins ,, Joshua Parsons, Maxwell Jones,, Christopher...Dunn,, Monica T. Kalichevsky-Dong,, Benjamin Pulford,, Iyad Dajani,, Kunimasa Saitoh,, Stephen P. Palese,, Eric Cheung,, Liang Dong c. THIS PAGE The...ytterbium-doped all-solid photonic bandgap fiber with ~1150µm2 effective mode area Fanting Kong,1,* Guancheng Gu,1 Thomas W. Hawkins ,1 Joshua Parsons

  20. Novel targeted nuclear imaging agent for gastric cancer diagnosis: glucose-regulated protein 78 binding peptide-guided 111In-labeled polymeric micelles

    Directory of Open Access Journals (Sweden)

    Cheng CC

    2013-04-01

    Full Text Available Chun-Chia Cheng,1,2,* Chiung-Fang Huang,3,4,* Ai-Sheng Ho,5 Cheng-Liang Peng,6 Chun-Chao Chang,7,8 Fu-Der Mai,1,9 Ling-Yun Chen,10 Tsai-Yueh Luo,2 Jungshan Chang1,11,121Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, 2Institute of Nuclear Energy Research, Atomic Energy Council, Taoyuan, 3School of Dental Technology, Taipei Medical University, Taipei, 4Division of Family and Operative Dentistry, Department of Dentistry, Taipei Medical University Hospital, Taipei, 5Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, 6Institute of Biomedical Engineering, National Taiwan University, Taipei, 7Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, 8Department of Internal Medicine, Taipei Medical University, Taipei, 9Department of Biochemistry, Taipei Medical University, Taipei, 10Institute of Biochemistry and Biotechnology, Chung Shan Medical University, Taichung, 11Neuroscience Research Center, Taipei Medical University Hospital, Taipei, 12Research Center for Biomedical Implants and Microsurgery Devices, Taipei Medical University, Taipei, Taiwan*These authors contributed equally to this workAbstract: Increased expression of cellular membrane bound glucose-regulated protein 78 (GRP78 is considered to be one of the biomarkers for gastric cancers. Therefore, peptides or molecules with specific recognition to GRP78 can act as a guiding probe to direct conjugated imaging agents to localized cancers. Based on this rationale, GRP78-guided polymeric micelles were designed and manufactured for nuclear imaging detection of tumors. Thiolated GRP78 binding peptide (GRP78BP was first labeled with maleimide-terminated poly(ethylene glycol–poly(ε-caprolactone and then mixed with diethylenetriaminepentaacetic acid (DTPA-linked poly(ethylene glycol–poly(ε-caprolactone to form DTPA/GRP78BP-conjugated micelles. The coupling efficiency of micelles with

  1. Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress

    Directory of Open Access Journals (Sweden)

    Lin ZC

    2016-08-01

    Full Text Available Zih-Chan Lin,1,* Chiang-Wen Lee,2,3,* Ming-Horng Tsai,4 Horng-Huey Ko,5 Jia-You Fang,1,2 Yao-Chang Chiang,6,7 Chan-Jung Liang,8,9 Lee-Fen Hsu,10 Stephen Chu-Sung Hu,11,12 Feng-Lin Yen5,8,13 1Graduate Institute of BioMedical Sciences, Chang Gung University, 2Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Kweishan, Taoyuan, 3Division of Basic Medical Sciences, Department of Nursing, Chang Gung Institute of Technology and Chronic Diseases and Health Promotion Research Center, Chiayi, 4Division of Neonatology and Pediatric Hematology/Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, Yunlin, 5Department of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 6Center for Drug Abuse and Addiction, China Medical University Hospital, 7Center for Drug Abuse and Addiction, China Medical University, Taichung, 8Center for Lipid and Glycomedicine Research, Kaohsiung Medical University, Kaohsiung, 9Center for Lipid Biosciences, Kaohsiung Medical University Hospital, 10Department of Respiratory Care, Chang Gung University of Science and Technology, Chiayi Campus, Chiayi, 11Department of Dermatology, College of Medicine, Kaohsiung Medical University, 12Department of Dermatology, Kaohsiung Medical University Hospital, 13Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan, Republic of China *These authors contributed equally to this work Abstract: Exposure to particulate matter (PM, a major form of air pollution, can induce oxidative stress and inflammation and may lead to many diseases in various organ systems including the skin. Eupafolin, a flavonoid compound derived from Phyla nodiflora, has been previously shown to exhibit various pharmacological activities, including antioxidant and anti-inflammatory effects. Unfortunately, eupafolin is characterized by poor water solubility and skin penetration, which limits its clinical

  2. Nimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial

    Directory of Open Access Journals (Sweden)

    Liang J

    2013-11-01

    Full Text Available Jun Liang,1 Mingyan E,2 Gang Wu,3 Lujun Zhao,4 Xia Li,5 Xia Xiu,6 Ning Li,1 Bo Chen,1 Zhouguang Hui,1 Jima Lv,1 Hui Fang,1 Yu Tang,1 Nan Bi,1 Wenqing Wang,1 Yirui Zhai,1 Tao Li,1 Dongfu Chen,1 Shuangmei Zou,7 Ning Lu,7 Rolando Perez-Rodríguez,8 Junqi Zheng,9 Luhua Wang11Department of Radiotherapy, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; 2Department of Radiotherapy, Cancer Hospital of Harbin Medical University, Harbin, People's Republic of China; 3Department of Radiotherapy, Tongji Cancer Center Hospital, Wuhan, People's Republic of China; 4Department of Radiotherapy, Cancer Hospital of Tianjin Medical University, Tianjin, People's Republic of China; 5Department of Radiotherapy, LiaoNing Province Cancer Hospital, Shenyang, People's Republic of China; 6Department of Radiotherapy, Beijing Hospital, Beijing, People's Republic of China; 7Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; 8Center of Molecular Immunology, Havana, Cuba; 9School of Medicine, Tongji University, Shanghai, People's Republic of ChinaObjective: To determine the safety and therapeutic effects of nimotuzumab (h-R3 combined with radiotherapy in esophageal cancer.Methods: This Phase II clinical trial involved 42 patients with stage II (inoperable or refused surgery to stage IV (supraclavicular lymph node metastasis only esophageal cancers treated between November 2008 and July 2010. All patients had squamous cell carcinomas, and all received three-dimensional conformal radiotherapy and 200 mg nimotuzumab per week during radiotherapy.Results: There were 9, 25, and 8 patients with stage II, III and IV disease, respectively. All except two patients received 50–70 Gy radiation; 37 patients (88.1% received more than five nimotuzumab doses. Grade III toxicities (21.4% of all adverse events included esophagitis and gastrointestinal, dermatological and hematological

  3. Potential role of pre- and postnatal testosterone levels in attention-deficit/hyperactivity disorder: is there a sex difference?

    Directory of Open Access Journals (Sweden)

    Wang LJ

    2017-05-01

    Full Text Available Liang-Jen Wang,1,2 Miao-Chun Chou,1 Wen-Jiun Chou,1 Min-Jing Lee,1 Sheng-Yu Lee,3,4 Pao-Yen Lin,5 Yi-Hsuan Lee,1 Yi-Hsin Yang,6 Cheng-Fang Yen2,7 1Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 2Department of Psychiatry, School of Medicine, and Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, 3Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, 4Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, 5Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, 6School of Pharmacy, Kaohsiung Medical University Hospital, 7Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan Objective: Both prenatal testosterone (T exposure and postnatal T levels have been associated with developing neural circuitry and behavioral systems. This study examined the potential correlation between pre- and postnatal T levels and behavioral and neurocognitive profiles of children with attention-deficit/hyperactivity disorder (ADHD.Methods: Two hundred ADHD patients with a mean age of 8.7±2.0 years (158 boys and 42 girls were recruited. The ratio of the length of the right index finger (2D to that of the right ring finger (4D (2D/4D ratio served as a surrogate of prenatal T exposure, and postnatal T was determined using salivary T concentration. Behavioral symptoms were evaluated using the Swanson, Nolan, and Pelham – Version IV Scale for ADHD (SNAP-IV. Neurocognitive function was assessed using the Wechsler Intelligence Scale for Children – Fourth Edition (WISC-IV and Conners’ Continuous Performance Test (CPT.Results: Lower 2D/4D ratios were associated with comorbid disruptive behavior disorders (t=2.15, P=0.033 in all participants. Among the boys with ADHD, neither 2D/4D ratios nor salivary T levels

  4. Enhancement of osseointegration of polyethylene terephthalate artificial ligament by coating of silk fibroin and depositing of hydroxyapatite

    Directory of Open Access Journals (Sweden)

    Jiang J

    2014-09-01

    Full Text Available Jia Jiang,1,2 Fang Wan,1 Jianjun Yang,1 Wei Hao,3 Yaxian Wang,3 Jinrong Yao,3 Zhengzhong Shao,3 Peng Zhang,1 Jun Chen,1 Liang Zhou,4 Shiyi Chen11Fudan University Sports Medicine Center and Department of Sports Medicine and Arthroscopy Surgery, Huashan Hospital, 2State Key Laboratory of Molecular Engineering of Polymers, 3Laboratory of Advanced Materials, National Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, People’s Republic of China; 4Department of Forest Products, Anhui Agricultural University, Hefei Anhui Province, People’s Republic of ChinaBackground: Application of artificial ligament in anterior cruciate ligament reconstruction is one of the research focuses of sports medicine but the biological tendon–bone healing still remains a problem. The preliminary study of hydroxyapatite (HAP coating on the polyethylene terephthalate (PET surface could effectively induce the osteoblast differentiation, but the tendon–bone healing was still not stable. As a green synthesis process, the biomimetic mineralization can simulate the natural bone growth in vitro and in vivo.Methods: HAP crystals were grown under the guide of silk fibroin (SF PET surface by biomimetic route. Several techniques including scanning electron microscopy, attenuated total reflectance Fourier transform infrared spectroscopy, X-ray diffraction, and energy-dispersive X-ray spectroscopy were utilized for proving the introduction of both SF and HAP. The viability and osseointegration of bone marrow stromal cells on the surface of three kinds of ligament, including PET group (non-coating group, PET+SF group (SF-coating group, and PET+SF+HAP group (combined HAP- and SF-coating group, were analyzed by CCK-8 assays and alkaline phosphatase (ALP detection. Seventy-two mature male New Zealand rabbits were randomly divided into three groups. Among them, 36 rabbits were sacrificed for mechanical testing, and

  5. Chemical constituents of Cyperus rotundus L. and their inhibitory ...

    African Journals Online (AJOL)

    in the genus Cyperus of the family Cyperaceae, which is pungent, slightly ... African Health Sciences Vol 16 Issue 4, December, 2016. 1000 ... L. purchased was identified by Teach- er Fang ..... Evaluation of Bcl-2 and Bax protein expressions.

  6. among pregnant women in southern Nigeria

    African Journals Online (AJOL)

    EB

    million people die annually of HBV- related chronic liver disease. Maternal ... Neonatal contamination does occur during labour and delivery ..... infection: a multicenter randomized double blind ... Su GG, Pan KH, Zhao NF, Fang SH, Yang DH,.

  7. Sun et al., Afr J Tradit Complement Altern Med. (2013) 10(6):563 ...

    African Journals Online (AJOL)

    cadewumi

    1Affiliated Hospital of Shandong University of Traditional Chinese Medicine & Pharmaceuticals, Jinan 250011, SD, .... Fracture of nasal bone. 1. Fang, 2007. Protrusion .... Discussion. Relationship between allergic shock and gender and ages.

  8. Brassia campestris L. ssp. chinensis L.var. utilis Tsen et Lee

    African Journals Online (AJOL)

    omodibo

    2012-12-31

    Dec 31, 2012 ... The pathogens were isolated by tissue segment method (Fang,. 1996) on potato ... Genomic DNA was extracted from a suspension culture of A. alter- nata by the cetyltrimethyl ... sample of orchid tissue. Biotechniques.

  9. Pectinolytic complex production by Aspergillus niger URM 4645 ...

    African Journals Online (AJOL)

    SAM

    2014-08-06

    Aug 6, 2014 ... organisms in the enzyme industry because as much as ... industrial residues or wastes are generally considered ... enzyme production processes reduces the cost of ... because they offer several economic benefits (Fang et.

  10. Primary structure and subcellular localization of two fimbrial subunit-like proteins involved in the biosynthesis of K99 fibrillae.

    Science.gov (United States)

    Roosendaal, E; Jacobs, A A; Rathman, P; Sondermeyer, C; Stegehuis, F; Oudega, B; de Graaf, F K

    1987-09-01

    Analysis of the nucleotide sequence of the distal part of the fan gene cluster encoding the proteins involved in the biosynthesis of the fibrillar adhesin, K99, revealed the presence of two structural genes, fanG and fanH. The amino acid sequence of the gene products (FanG and FanH) showed significant homology to the amino acid sequence of the fibrillar subunit protein (FanC). Introduction of a site-specific frameshift mutation in fanG or fanH resulted in a simultaneous decrease in fibrillae production and adhesive capacity. Analysis of subcellular fractions showed that, in contrast to the K99 fibrillar subunit (FanC), both the FanH and the FanG protein were loosely associated with the outer membrane, possibly on the periplasmic side, but were not components of the fimbriae themselves.

  11. Pop / Koit Raudsepp

    Index Scriptorium Estoniae

    Raudsepp, Koit

    2004-01-01

    Heliplaatidest: Raekwon "The Lex Diamond Story", Nelly Furtado "Folklore", The Distillers "Coral Fang", Erinevad esitajad "The Texas Chainsaw Massacre - The Album", Soel (Ohse, Pascal & St Germain) "Memento", Donato Wharton "Trabanten", The Von Bondies "Pawn Shoppe Heart"

  12. [Raamat] / Juhan Kreem

    Index Scriptorium Estoniae

    Kreem, Juhan

    2003-01-01

    Rets. rmt.: Jahnke, Carsten. Das Silber des Meeres. Fang und Vertrieb von Ostseehering zwischen Norwegen und Italien (12.-16. Jahrhundert). Quellen und Darstellungen zur hansischen Geschichte N. F. Köln, Weimar, Wien, 2000

  13. Chinese wood frame buildings and the changing dimensions of their structural components in different time periods

    Directory of Open Access Journals (Sweden)

    Nujaba Binte Kabir

    2012-06-01

    Full Text Available The Features of the Chinese wood frame buildings are same in character from dynasty to dynasty. The study concentrates on 9 Chinese wood frame buildings from Tang to Yuan dynasty and tries to relate these buildings with the text described in a building manual book published in Song dynasty Yingzao fashi. The features of some buildings match with the text described in the book some do not. But on the other hand Liang Sicheng, scholar of Chinese architecture in his book claimed that Chinese wood frame architecture has a unique system of characteristics (Liang, 1984. The system of wood frame Chinese architecture did not change but the proportion of the features has changed in different dynasty. The aim of the paper is to compare the features of the buildings those have been studied according to Yingzao fashi with Liang's observation on the change of building style in different periods.

  14. Wide Band Gap Semiconductors Symposium Held in Boston, Massachusetts on 2-6 December 1991. Materials Research Society Symposium Proceedings. Volume 242

    Science.gov (United States)

    1992-01-01

    AND PROPERTIES OF WIDE BAND-GAP Il-VI STRAINED- LAYER SUPERLATTICE 227 Hailong Wang. Jie Cui. Aidong Shen. Liang Xu, Yunliang Chen. and Yuhua Shen IN...WANG JIE CUI AIDONG SHEN LIANG XU YUNLIANG CHEN AND YUHUA SHEN Shanghai Institute of Optics and Fine Mechanics, Academia Sinica P.O.Box 800-216 Shanghai...He Zujou, Cao Huazhe, Su Wuda, Chen Zhongcai, Zhon Feng and Wang Erguang, Thin Solid Films, 139,261(1986). 22) Xin Li and T.L.Tansley, J.AppI.Phys

  15. Mesozooplankton distribution near an active volcanic island in the Andaman Sea (Barren Island)

    Digital Repository Service at National Institute of Oceanography (India)

    Pillai, H.U.K.; Jayaraj, K.A.; Rafeeq, M.; Jayalakshmi, K.J.; Revichandran, C.

    predation might happened in the surface. Copepods are important food items for chaetognaths (Liang and Vega-Pérez 1995), and they play an extremely important role in energy transfer to higher trophic levels (Terazaki 1998; Fulmer and Bollens 2005). It has... volcanic signature observed around Barren Island, Andaman Sea, India. Marine Geophysical Researches. doi:10.1007/ s11001–006–9008-z. Liang, T. H., & Vega-Pérez, L. A. (1995). Studies on chaetognaths off Ubatuba region, Brazil. II. Feeding habits...

  16. Studies on the relationship between cyanide-resistant respi-ration and expression of alternative oxidase in mung bean using antibodies prepared by synthetic polypeptide

    Institute of Scientific and Technical Information of China (English)

    LI; Chijun; (

    2001-01-01

    [1]Liang, Z., Liang, H. G., The respiratory metabolism of plants, in Plant Physiology and Molecular Biology (eds. Yu, S. W., Tang, Z. C.) (in Chinese), 2nd ed., Beijing: Science Press, 1998, 344-365.[2]Lü, C. S., Liang, H. G., Induced respiration in melon fruits, Scientia Sinica, 1963, 12(4): 616.[3]Liang, H. G., Lü, C. S., A comparative study of CN-resistant respiration in different cultures of tobacco callus, Plant Physiol., 1984, 75: 876.[4]Elthon, T. E., McIntosh, L., Identification of the alternative terminal oxidase of higher plant mitochondria, Proc. Natl. Acad. Sci. USA, 1987, 84: 8399.[5]Elthon, T. E., Nickels, R. L., McIntosh, L., Monoclonal antibodies to the alternative oxidase of higher plant mitochondria, Plant Physiol., 1989, 89: 1311.[6]Liang, W. S., Liang, H. G., Progress of the alternative oxidase, Chinese Bulletin of Botany (in Chinese), 1997, 14(2): 9.[7]Liang, W. S., Liang, H. G., Induction of alternative oxidase expression by endogenous ethylene in aging potato slices, Acta Phytophysiol. Sin. (in Chinese), 1999, 25(2): 205.[8]He, J. X., Wei, Z. Q., Liang, H. G., Effects of water stress on development, and operation and gene expression of cyanide-resistant respiratory pathway in wheat, Science in China, Ser. C, 1999, 42(3): 300.[9]McIntosh, L., Molecular biology of the alternative oxidase, Plant Physiol., 1994, 105: 781.[10] Wang, J., Zhang, L. X., Liu, Z. L. et al., A possible calcium binding site in D1 protein: A fluorescence and FTIR study of the interaction between lanthanides and a synthetic peptide, Photosynthesis Research, 1995, 44: 297.[11] Li, X. P., Du, L. F., Liang, H. G. et al., Preparation and identification of antidodecapeptide of polypeptide D1 or photosys-tem II reaction center, Prog. Biochem. Biophys. (in Chinese), 1997, 24(3): 283.[12] Wen, J. Q., Liang, H. G., Studies on energy status and mitochondria respiration during growth and senescence of mung bean cotyledons, Physiol

  17. High-Order Numerical Methods for the Simulation of Linear and Nonlinear Waves: High-Frequency Radiation and Dynamic Stability

    Energy Technology Data Exchange (ETDEWEB)

    Nicholls, David P. [UIC-MSCS

    2014-04-23

    Over the past four years the Principal Investigator (PI) David Nicholls has worked on several projects in connection with award DE-SC0001549. Of the greatest import has been the continued supervision of ve Ph.D. students (Robyn Canning, Travis McBride, Andrew Sward, Zheng Fang, and Venu Tammali). Canning and McBride defended their theses and graduated in May 2012, while Sward defended his thesis and graduated in May 2013. Both Fang and Tammali plan to defend their theses within the year and graduate in May 2015. Fang is now a very experienced graduate researcher with one paper accepted for publication and another in preparation. Tammali is nearly to the point of writing a paper and will work this summer as an intern at Argonne National Laboratory in the Mathematics and Computer Science Division under the supervision of Paul Fischer.

  18. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    DEFANG GAN1 MENGDAN ZHAN1 FENG YANG1 QIQI ZHANG1 KELING HU1 WENJUAN XU1 QINGHUI LU2 LING ZHANG1 DANDI LIANG1. School of Horticulture, Anhui Agricultural University, Hefei 230036, People's Republic of China; Modern Agricultural Science and Technology Cooperative Extension Service Center ...

  19. Evaluation of effectiveness in a novel wound healing ointment ...

    African Journals Online (AJOL)

    Evaluation of effectiveness in a novel wound healing ointment-crocodile oil burn ointment. Hua-Liang Li, Yi-Tao Deng, Zi-Ran Zhang, Qi-Rui Fu, Ya-Hui Zheng, Xing-Mei Cao, Jing Nie, Li-Wen Fu, Li-Ping Chen, You-Xiong Xiong, Dong-Yan Shen, Qing-Xi Chen ...

  20. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Home; Journals; Journal of Astrophysics and Astronomy; Volume 35; Issue 3. Correlations between Optical Variability and Physical Parameters of Quasars. Wenwen Zuo Xue-Bing Wu Yi-Qing Liu Cheng-Liang Jiao. Part V: Black Holes (or Binary Black Holes) in Blazars Volume 35 Issue 3 September 2014 ...

  1. Advances in SCA and RF-DNA Fingerprinting Through Enhanced Linear Regression Attacks and Application of Random Forest Classifiers

    Science.gov (United States)

    2014-09-18

    22:477– 505 , 2007. [21] Bushnell, Michael L. and Vishwani Agrawal. Essentials of Electronic Testing for Digital, Memory, and Mixed-Signal VLSI...Investigation”. Knowledge and information systems, 10(4):453–472, 2006. [68] Liang, Nia -Chiang, Ping-Chieh Chen, Tony Sun, Guang Yang, Ling-Jyh Chen

  2. New Competition; Foreign Direct Investment and Industrial Development in China

    NARCIS (Netherlands)

    G. Liang

    2004-01-01

    textabstractGuoyong Liang is completing his Ph.D. in international business and works at the Rotterdam School of Management, Erasmus University. His current research interests include the theory of the multinational enterprise, business strategy, and business/government interaction. Before his Ph.D.

  3. Electrochemical investigation of NO at single-wall carbon nanotubes ...

    Indian Academy of Sciences (India)

    Administrator

    potential sweep was 300–1400 mV. The EIS was ..... –1 . NO (as shown in scheme 1) is summed up in the equation. 45,46 .... Yu A, Liang Z J, Cho J H and Caruso F 2003 Nano. Lett. 3 1203 ... Veen J A R and Koper M T M 2004 Electrochim.

  4. High harmonic generation in H and HD by intense femtosecond ...

    Indian Academy of Sciences (India)

    2013-04-24

    Apr 24, 2013 ... We have argued that for these conditions the harmonic generation due to the transitions in the electronic ... (XUV) or soft X-ray range and generation of very high-energy attosecond (as) pulses have been widely ..... [3] Y Liang, S Augst, S L Chin, Y Beaudoin and M Chaker, J. Phys. B 27, 5119 (1994).

  5. Microstructural and optical properties of transparent conductive ZnO ...

    Indian Academy of Sciences (India)

    Administrator

    College of Materials Science and Engineering, Shaanxi University of Science and Technology, China 710021 ..... (in press). Gorla C R, Emanetoglu N W, Liang S, Mayo W E and Lu Y. 1999 J. Appl. Phys. ... Shin E W and Park C 2007 Mater.

  6. Creating a Culture of Student Success: The SEEK Scholars Peer Mentoring Program

    Science.gov (United States)

    Zevallos, Ana L.; Washburn, Mara

    2014-01-01

    Over the past decades, Vincent Tinto, Edmund Thile, Francis Ianni, and others all link mentoring to better academic performance, improved social adjustment, enhanced academic experiences, and greater rates of degree completion. Even more specifically, Jean E. Rhodes, Renée Spencer, Thomas E. Keller, Belle Liang, and Gil Noam describe three…

  7. Untitled

    Indian Academy of Sciences (India)

    upgrade its performance such as endurance of the material at elevated temperatures. Heat deflection temperature. (HDT) has been reported to increase with increase of PC content in PP (Liang and Williams 1991). Dimensional stability, HDT, modulus of polymers and polyblends are further improved by the incorporation of ...

  8. Effects of various forms of lipopolysaccharide on the expression of ...

    African Journals Online (AJOL)

    Jane

    2011-10-05

    Oct 5, 2011 ... Lan-jun Bai1, Wings TY Loo2,3,4*, Yiding Dou4, Min Wang5, Hao Liang5, Mary NB Cheung3,4,6 ... The levels of lactate dehydrogenase (LDH), N-terminal pro ...... Li G-R, Sun H-Y, Chen J-B, Zhou Y, Tse H-F, Lau C-P (2009).

  9. Structure Variation from One-Dimensional Chain to Three ...

    Indian Academy of Sciences (India)

    WEN-XUAN LI, XIAO-MIN GU, WEN-LI ZHANG and LIANG NI. School of Chemistry ... Compound 1 possesses one-dimensional chain structure, and expands into ..... sis of fine chemicals and pharmaceuticals.30 The results were summarized ...

  10. Association of HS6ST3 gene polymorphisms with obesity and ...

    Indian Academy of Sciences (India)

    Supplementary data: Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction. Ke-Sheng Wang, Liang Wang, Xuefeng Liu and Min Zeng. J. Genet. 92, 395–402. Table 1. Associations of 117 SNPs with obesity in the Health ABC and Marshfield samples. Minor. OR Health.

  11. Browse Title Index

    African Journals Online (AJOL)

    Items 501 - 550 of 1309 ... HH Tamboura, B Bayala, M Lompo, IP Guissou, L Sawadogo ... X Wang, Y-G Chen, L Ma, Z-H Li, J-Y Li, X-G Liu, J-L Zou, J-H Wu. Vol 11, No 2 ... Zhi-Jiang Wang, Wei Xu, Jian-Wen Liang, Cai-Sheng Wang, Yani Kang.

  12. Structural investigation of V2O5–P2O5–K2O glass system with ...

    Indian Academy of Sciences (India)

    Metal ions such as cobalt and vanadium and their metal- complexes ... In this context, the new potassium–phosphate glass sys- ... A single 'glass water-extract' ..... [22] Zhang W G and Liang J H 2013 Synth. React. Inorg. Met-Org. Nano-Met.

  13. jinping feng

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. JINPING FENG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING FENG ...

  14. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Philip N Garner. Articles written in Sadhana. Volume 36 Issue 5 October 2011 pp 885-915. Current trends in multilingual speech processing · Hervé Bourlard John Dines Mathew Magimai-Doss Philip N Garner David Imseng Petr Motlicek Hui Liang Lakshmi Saheer Fabio Valente · More Details ...

  15. African Journal of Biotechnology - Vol 11, No 14 (2012)

    African Journals Online (AJOL)

    DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. HD Ding, HJ Zhang, XH Zhu, H Liu, JS Liang, B Lu, 3259-3269 ... DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Y Hanying, X Wei, G Xingxi, 3370-3378 ... FULL TEXT DOWNLOAD FULL TEXT. J Zhang, YC Huang, Q Zhang, ZP Hong, YC Zhou, WL Chen, 3388-3393 ...

  16. 75 FR 18154 - Notice of Initiation of Administrative Reviews and Requests for Revocation in Part of the...

    Science.gov (United States)

    2010-04-09

    ...., Ltd Asian Seafoods (Zhanjiang) Co., Ltd Beautiful Lighting Co., Ltd....... Beihai Qinguo Frozen Foods... Liang Hsin Lighting Shenzhen...... Maoming Changxing Foods Maoming Jiahui Foods Co., Ltd..... New Peak...... Rizhao Smart Foods Ruian Huasheng Aquatic Products Fac Savvy Seafood Inc Sea Trade International Inc...

  17. Reference: 169 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available e M et al. 2005 Mar. Plant J. 41(5):744-54. The recessive Arabidopsis thalianafumonisin B1-resistant (fbr6) ...opment and sensitivity to fumonisin B1. 5 744-54 15703061 2005 Mar The Plant journal Liang Xinwen|Nekl Emily R|Stiers Justin J|Stone Julie M

  18. Improvements in medium range weather forecasting system of India

    Indian Academy of Sciences (India)

    system is based on the latest Grid Statistical Interpolation (GSI) scheme and it has the provision to use most of .... ified Simplified-Arakawa Scheme (SAS) (Han and. Pan 2010). ..... Kim Y-J and Arakawa A 1995 Improvement of orographic gravity wave ... Yang F, Mitchell K, Hou Y-T, Dai Y, Deng X, Wang Z and. Liang X-Z ...

  19. Further improvement of N6 medium for callus induction and plant ...

    African Journals Online (AJOL)

    user

    2011-03-02

    Mar 2, 2011 ... bryos before or after transformation (Wang et al., 2009). Comparing to rice and ... regeneration, which heavily depends on several model inbred lines, such as ..... Tang FD, Liang YJ, Han SJ, Gong WG, Ding BY (2004). Effect of ... Wang K, Frame B, Ishida Y, Komari T (2009) Maize Genetic. Transformation.

  20. The Ser311Cys variation in the paraoxonase 2 gene increases the ...

    Indian Academy of Sciences (India)

    Supplementary data: The Ser311Cys variation in the paraoxonase 2 gene increases the risk of type 2 diabetes in northern Chinese. Yanchun Qu, Ze Yang, Feng Jin, Liang Sun, Chuanfang Zhang, Linong Ji, Hong Sun, Binyou Wang and Li Wang. J. Genet. 87, 165–169. Table 1. Clinical characteristics of case and control.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus · Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang · More Details Abstract Fulltext PDF. The use of adenovirus vector-based ...

  2. induced by NF-κB Decoy method

    African Journals Online (AJOL)

    control of immunity. Nature. 1998; 392(6673):245-252. Kabalak G, Dobberstein SB, Matthias T, Reuter S,. 5. The YH, Dorner T, Schmidt RE, Witte T. Association of immunoglobulin-like transcript 6 deficiency with. Sjogren's syndrome. Arthritis Rheum. 2009; 60(10):2923-. 2925. Bonham CA, Peng L, Liang X, Chen Z, Wang L, ...

  3. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. YAN HUI GENG. Articles written in Sadhana. Volume 43 Issue 3 March 2018 pp 34. Spectral element method for wave propagation on irregular domains · YAN HUI GENG GUO LIANG QIN JIA ZHONG ZHANG · More Details Abstract Fulltext PDF. A spectral element approximation of acoustic ...

  4. Rapid cloning and bioinformatic analysis of spinach Y chromosome ...

    Indian Academy of Sciences (India)

    Rapid cloning and bioinformatic analysis of spinach Y chromosome- specific EST sequences. Chuan-Liang Deng, Wei-Li Zhang, Ying Cao, Shao-Jing Wang, ... Arabidopsis thaliana mRNA for mitochondrial half-ABC transporter (STA1 gene). 389 2.31E-13. 98.96. SP3−12. Betula pendula histidine kinase 3 (HK3) mRNA, ...

  5. Indexes to Volume 67

    Indian Academy of Sciences (India)

    Exact solutions to a class of nonlinear Schrödinger-type equations. Jin-Liang Zhang .... Determination of thorium and uranium contents in soil samples using. SSNTD's ... Direct determination of bulk etching rate for LR-115-II solid state nuclear.

  6. Risk factors of virologic failure and slow response to art among HIV ...

    African Journals Online (AJOL)

    Risk factors of virologic failure and slow response to art among HIV-infected children and adolescents in Nairobi. J. M. Kabogo, S. Gupta, A. K. Maina, M. Ochwoto, R. W. Omange, R. N. Musoke, R. W. Lihana, E. Muniu, F. W. Wamunyokoli, B. Liang, E. M. Songok ...

  7. Fraction against Human Cancer Cell Lines

    African Journals Online (AJOL)

    fraction of A. sieberi against seven cancer cell lines (Colo20, HCT116, DLD, MCF7, Jurkat, HepG2 and ... The morphology of the HepG2 cell nucleus was investigated by Hoechst 33342, ..... Gong F, Liang Y, Xie P, Chau F. Information theory.

  8. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Author Affiliations. X. Chen1 G. Fossati1 E. Liang1 M. Böttcher2. Department of Physics and Astronomy, Rice University, Houston, Texas 77005, USA. Department of Physics and Astronomy, Astrophysical Institute, Ohio University, Athens, Ohio 45701, USA.

  9. Browse Title Index

    African Journals Online (AJOL)

    Items 201 - 250 of 2037 ... Vol 14, No 11 (2015), Antibacterial Activity and Mode of Action of Mentha arvensis Ethanol Extract against Multidrug-Resistant Acinetobacter baumannii, Abstract PDF. Ling Zhang, Shu-gen Xu, Wei Liang, Jun Mei, Yue-ying Di, Hui-hua Lan, Yan Yang, Wei-wei Wang, Yuan-yuan Luo, Hou-zhao Wang.

  10. Tropical Journal of Pharmaceutical Research - Vol 14, No 11 (2015)

    African Journals Online (AJOL)

    Antibacterial Activity and Mode of Action of Mentha arvensis Ethanol Extract against Multidrug-Resistant Acinetobacter baumannii · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ling Zhang, Shu-gen Xu, Wei Liang, Jun Mei, Yue-ying Di, Hui-hua Lan, Yan Yang, ...

  11. Isolation and characterization of sixty sequences of cot-1 DNA from ...

    African Journals Online (AJOL)

    user

    2012-11-06

    Nov 6, 2012 ... this study were from U. t. ussuricus animals raised in the Beijing. Zoo. ..... Collins F, Guyer MS, Peterson J, Felsenfeld A, Wetterstrand KA,. Patrinos A ... B, Ni P, Lin R, Qian W, Wang G, Yu C, Nie W, Wang J, Wu Z, Liang.

  12. c-Fos expression in the paternal mouse brain induced by communicative interaction with maternal mates

    OpenAIRE

    鍾, 静; Zhong, Jing

    2014-01-01

    博士論文要旨Abstract 以下に掲載:Molecular Brain 7(66) pp.1-11 2014. BioMed Central. 共著者:Jing Zhong, Mingkun Liang, Shirin Akther, Chiharu Higashida, Takahiro Tsuji, Haruhiro Higashida

  13. Estimating Energy Efficiency of Connected and Autonomous Vehicles in a Mixed Fleet

    Science.gov (United States)

    2018-05-01

    Jing Dong (orcid.org/0000-0002-7304-8430); Liang Hu (orcid.org/0000-0001-6351-8542); Chaoru Lu (orcid.org/0000-0001-8418-7658); Connected and autonomous vehicle (CAV) technologies are likely to be gradually implemented over time and in a traffic envi...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SHUGUANG HAN. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING ...

  15. Timeless is a critical gene in the diapause of silkworm, Bombyx mori ...

    African Journals Online (AJOL)

    Timeless is a critical gene in the diapause of silkworm, Bombyx mori. L Xu, H Liang, LP Gan, WD Wang, YH Sima, SQ Xu. Abstract. The diapause is a specific physiological phenomenon induced by circadian zeitgebers of temperature and photoperiod at the stage of maternal embryonic development. In this research, the ...

  16. Reconsidering Asian American Student Development

    Science.gov (United States)

    Kodama, Corinne M.; Maramba, Dina C.

    2017-01-01

    This chapter addresses the applicability of student development theories in light of empirical research on Asian American college students through a twofold approach: (a) revisiting the relevance of Kodama, McEwen, Liang, and Lee's (2001, 2002) theoretical work on Asian American student development; and (b) using Jones' and Stewart's (2016)…

  17. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. XINHUA WANG. Articles written in Journal of Biosciences. Volume 42 Issue 4 December 2017 pp 671-681 Article. MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 · LIANG BAO LEI LV JINPING ...

  18. Perceived Discrimination and Women's Psychological Distress: The Roles of Collective and Personal Self-Esteem

    Science.gov (United States)

    Fischer, Ann R.; Holz, Kenna Bolton

    2007-01-01

    In the spirit of counseling psychology's social justice mission (e.g., L. A. Goodman, B. Liang, J. E. Helms, R. E. Latta, E. Sparks, & S. R. Weintraub, 2004), the authors examined perceptions of discrimination against women as related to women's views of the group women, their views of themselves as individuals, and their psychological…

  19. Calycosin regulates glucocorticoid-induced apoptosis via Nrf2/ARE ...

    African Journals Online (AJOL)

    Lifeng Fu1, WeiLiang Wu2, Jian Zhu2, Shu Qiang2, Jansong Chen2* ... Results: CA reduced the apoptosis and accumulation of ROS in DEX-treated cells. ..... its downstream effectors (Figure 5 A-C). However .... Cao J, Chen Z, Zhu Y, Li Y, Guo C, Gao K, Chen L, Shi ... Hong W. Experimental study on the effect of Calycosin.

  20. Boric acid as a mild and efficient catalyst for one-pot synthesis of 1 ...

    Indian Academy of Sciences (India)

    4, July 2012, pp. 927–931. c ..... 35 45. 4. Kantevari S, Vuppalapati S V N and Nagarapu L 2007. Catal. ... Chem. Lett. 18 788. 12. Nandi G C, Samai S, Kumar R and Singh M S 2009 ... Wang M, Song Z G and Liang Y 2012 Synthetic Com- mun.

  1. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (86th, Kansas City, Missouri, July 30-August 2, 2003). Advertising Division.

    Science.gov (United States)

    2003

    The Advertising Division of the proceedings contains the following 20 papers: "Stereotyping the 'Model Minority': A Longitudinal Analysis of U.S. Primetime Network Commercials, Comparing Asian Female and Male Characters to Themselves and Others" (Dennis J. Ganahl, Liang Ge and Kwangok Kim); "Cultivation Effects of Television…

  2. Increased Vulnerability to Soman Exposure in Aged Compared to Adult F344 Rats

    Science.gov (United States)

    2016-10-01

    determination of AChE and BChE levels in unprocessed whole blood. Paper presented at the CBMTS III, Spiez, Switzerland. Feaster, S. R., Gordon, R. K... albumin esterase, but not carboxylesterase, are present in human plasma. Biochem Pharmacol, 70(11), 1673- 1684. doi: 10.1016/j.bcp.2005.09.002 Liang

  3. Study of neutron-rich Mo isotopes by the projected shell model ...

    Indian Academy of Sciences (India)

    But because of the low statistics and contamination, it was not possible to calculate g exp .... violated in the deformed single-particle states is fully restored by the angular-momentum- projection method ...... the yrast states have composite structure. ..... [14] M Liang, H Ohm, B De Sutter and K Sistemich, Z. Phys. A 344, 357 ...

  4. African Journal of Biotechnology - Vol 11, No 16 (2012)

    African Journals Online (AJOL)

    Subcellular localization of cadmium in hyperaccumulator Populus × canescens · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. HP Dai, C Shan, Y Wei, JG Liang, TX Yang, WQ Sa, AZ Wei, 3779-3787 ...

  5. Isolation and characterization of fourteen novel microsatellite loci ...

    Indian Academy of Sciences (India)

    [Liu Q., Li Y., Liang H. and Liu X. 2014 Isolation and characterization of fourteen ... management and conservation, little information is available on the genetic structure and genetic variation of B. lenok tsin- lingensis. Microsatellites are currently the markers of choice ... sue according to the simplified method of Laird et al.

  6. Co-expression of the C-terminal domain of Yersinia enterocolitica ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 1. Co-expression of the C-terminal domain of Yersinia enterocolitica invasin enhances the efficacy of classical swine-fever-vectored vaccine based on human adenovirus. Helin Li Pengbo Ning Zhi Lin Wulong Liang Kai Kang Lei He Yanming Zhang. Articles Volume ...

  7. First fossil insectivores from Flores

    NARCIS (Netherlands)

    Hoek Ostende, van den L.W.; Berch, van der G.; Awe Due, R.

    2006-01-01

    The hominid bearing strata from the Liang Bua cave on Flores have yielded a large amount of microvertebrate remains. Among these are three mandibles of shrews, the first record of fossil insectivores from the island. The fossils, representing two different species, are not referable to any of the

  8. Three new giant prehistoric rats from Flores, Lesser Sunda Islands

    NARCIS (Netherlands)

    Hooijer, D.A.

    1957-01-01

    The specimens described in the present paper have been collected by Dr. Th. L. Verhoeven at Liang Toge, a cave near Warukia, 1 km south of a hamlet called Lepa, in Manggarai, western Flores. This cave, as well as many others explored in the island by Verhoeven (1952, 1953), contains a Mesolithic

  9. Identification of a novel SHOX mutation in a Chinese family with ...

    Indian Academy of Sciences (India)

    [Mei L., Huang Y., Pan Q., Li H., Liang D. and Wu L. 2014 Identification of a novel SHOX mutation in a Chinese family with isolated. Madelung deformity. J. Genet. ... females than males (Lichtenstein et al. 1980; Grigelioniene et al. 2001). .... proteins play critical roles in controlling the embryonic development in vertebrates ...

  10. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Structure Variation from One-Dimensional Chain to Three-Dimensional Architecture: Effect of Ligand on Construction of Lanthanide Coordination Polymers. LEI WANG WEN-XUAN LI XIAO-MIN GU WEN-LI ZHANG LIANG NI. Regular Article Volume 129 Issue 2 ... Supplementary Material. JCSC_129_02_0271_0280_SI.doc ...

  11. Experimental Research Into High Barometric Oxygen Prevention of Guinea Pig Hearing Loss,

    Science.gov (United States)

    1992-08-28

    PREVENTION OF GUINEA PIG HEARING LOSS by Yin Jiacai, Sun Fang ren, et al. DTIC MLECTE •<• EP 2 9 1992 Approved for public release, Distribution unlimited...PREVENTION OF GUINEA PIG HEARING LOSS By: Yin Jiacai, Sun Fang ren, et al. English pages: 9 Source: Chung-Hua I Shueh Tsa Chih, Vol. 65, Nr. 11, Nov.eember...Distributionf._DL~~~t .•b • / or __ Dlist szeccat .lef ’ ~1 EXPERIMENTAL RESEARCH INTO HIGH BAROMETRIC OXYGEN PREVENTION OF GUINEA PIG HEARING LOSS BY: Yin

  12. Clinical Strategy for Optimal Traditional Chinese Medicine (TCM) Herbal Dose Selection in Disease Therapeutics: Expert Consensus on Classic TCM Herbal Formula Dose Conversion.

    Science.gov (United States)

    Zha, Lin-Hua; He, Li-Sha; Lian, Feng-Mei; Zhen, Zhong; Ji, Hang-Yu; Xu, Li-Peng; Tong, Xiao-Lin

    2015-01-01

    The clinical therapeutics of traditional Chinese medicine (TCM) constitutes a complicated process which involves theory, diagnosis, and formula prescription with specific herbal dosage. Zhang Zhong-Jing's classic work, Treatise on Febrile and Miscellaneous Diseases, has been influencing TCM practice for almost 2000 years. However, during this extended period of time in Chinese history, the Chinese weight measurement system experienced noticeable changes. This change in the weight measurement system inevitably, and perhaps even negatively, affected TCM herbal dosage determination and treatment outcome. Thus, in modern society, a full understanding of the accuracy of herbal dose selection has a critical importance in the TCM daily practice of delivering the best treatment to the patients suffering from different illnesses. In the 973 Project of the Chinese National Basic Research Program, expert consensus on classic TCM formula dose conversion has been reached based on extensive literature review and discussion on the dose-effect relationship of classic TCM formulas. One "liang" in classic TCM formulas is equivalent to 13.8 g. However, based on many TCM basic and clinical studies of variable herbal formula prescriptions and herbal drug preparations, the rule of one liang equals 13.8 g should be adjusted according to different disease conditions. Recommended by the committee on TCM formula dose-effect relationship of the China Association of Chinese Medicine and the World Federation of Chinese Medicine Societies, the following expert consensus has been reached: (i) One liang converts to 6-9 g for the severely and critically ill patients. (ii) One liang converts to 3-6 g for the patients suffering from chronic diseases. (iii) One liang converts to 1-3 g in preventive medicine. The above conversions should be used as a future TCM practice guideline. Using this recommended guideline should enhance the effectiveness of daily TCM practice.

  13. Abstracts from the 15th International Myopia Conference

    Directory of Open Access Journals (Sweden)

    Alexandra Benavente-Perez

    2016-11-01

    Full Text Available Table of contents O1 Changes in peripheral refraction associated with decreased ocular axial growth rate in marmosets Alexandra Benavente-Perez, Ann Nour, Tobin Ansel, Kathleen Abarr, Luying Yan, Keisha Roden, David Troilo O2 PPARα activation suppresses myopia development by increasing scleral collagen synthesis--a new drug target to suppress myopia development Chanyi Lu, Miaozhen Pan, Min Zheng, Jia Qu, Xiangtian Zhou O3 Evidence and possibilities for local ocular growth regulating signal pathways Christine F Wildsoet O4 Myopia researches at Eye Hospital of Wenzhou Medical University Fan Lu, Xiangtian Zhou, Jie Chen, Jinhua Bao, Liang Hu, Qinmei Wang, Zibing Jin, Jia Qu O5 Color, temporal contrast and myopia Frances Rucker, Stephanie Britton, Stephan Hanowsky, Molly Spatcher O6 The impact of atropine usage on visual function and reading performance in myopic school children in Taiwan Hui-Ying Kuo, Ching-Hsiu Ke, I-Hsin Kuo, Chien-Chun Peng, Han-Yin Sun O7 Increased time outdoors prevents the onset of myopia: evidence from randomised clinical trials Ian G Morgan O8 Environmental risk factors and gene-environment interactions for myopia in the ALSPAC cohort Jeremy A. Guggenheim, Rupal L. Shah, Cathy Williams O9 Retinal metabolic profiling identifies declines in FP receptor-linked signaling as contributors to form-deprived myopic development in guinea pigs Jinglei Yang, Peter S. Reinach, Sen Zhang, Miaozhen Pan, Wenfeng Sun, Bo Liu, Xiangtian Zhou O10 The study of peripheral refraction in moderate and high myopes after one month of wearing orthokeratology lens Jun Jiang, Haoran Wu, Fan Lu O11 Axial length of school children around the earth’s equatorial area and factors affecting the axial length Kazuo Tsubota, Hiroko Ozawa, Hidemasa Torii, Shigemasa Takamizawa, Toshihide Kurihara, Kazuno Negishi O12 Processing of defocus in the chicken retina by retinal ganglion cells Klaus Graef, Daniel Rathbun, Frank Schaeffel O13 Blue SAD light protects

  14. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 122; Issue 6. Synthesis and aggregation study of optically active tetra--[()-2-octanyloxy]-substituted copper and nickel phthalocyanines. Fang-Di Cong Gui Gao Jian-Xin Li Guo-Qing Huang Zhen Wei Feng-Yang Yu Xi-Guang Du Ke-Zhi Xing. Full Papers Volume ...

  15. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. QINGHUA NIE. Articles written in Journal of Genetics. Volume 90 Online resources 2011 pp e10-e20. Identification and characterization of the pig ABIN-1 gene and investigation of its association with reproduction traits · Meixia Fang Hongli Du Yongsheng Hu Xiaoning Zhou Hongjia ...

  16. Chinese Function Manager of 2006 Partenariat Comments on the Selection Principle for Chinese Enterprises

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Fang Lei, EU-China Partenariat 2006Function Manager for Chinese Host Companies, worked together with Mr. Richard Morgan, EU Project Expert,Mr. Han Meiqing, Chinese Project Expert in the primary selection of Chinese enterprises.In reply to the strong request of the relevant governmental institutions, CCPIT and enterprises, he gave the following introductions about the details of selection.

  17. Ecohealth Field-building Leadership Initiative in Southeast Asia ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institution. Kunming Institute of Botany, Chinese Academy of Sciences as represented by Sun Hang. Institution Country. China. Project Leader. Dr Fang Jing. Institution. Kunming Medical University as represented by Jiang Runsheng. Institution Country. China. Institution Website. http://www.kmmu.edu.cn. Project Leader.

  18. Using Knowledge about the Opponent in Game-Tree Search.

    Science.gov (United States)

    1992-09-01

    Schaeffer’s stimulating enthusiasm and dynamism spurred me on when I seemed to be stuck in perpetual check. Though I interacted with Jaime Carbonell...and Gene, Pierre, Fang and XiaoGang, Sabine and Consuelo. To them, and all the others I had to omit here, my sincere thanks. Finally, all of this

  19. Screening of Wheat Genotypes for Boron Efficiency in Bangladesh

    Science.gov (United States)

    A number of Bangladeshi wheat genotypes (varieties and advanced lines) have been tested for boron efficiency through sand culture experiments over two years (2007-08 & 2008-09) against two Thai check varieties ‘Fang 60’ (boron efficient) and ‘SW41’ (boron inefficient). Performances of the genotypes ...

  20. Effects of palm oil mill effluent (POME) anaerobic sludge from 500 m ...

    African Journals Online (AJOL)

    USER

    2010-04-19

    Apr 19, 2010 ... in the country (Lau et al., 2008). Thus, the ... within 80 days with final C/N ratio of 12.5. .... C/N ratio of pressed shredded EFB was 54.4 with carbon ..... Wong JWC, Mak KF, Chan NW, Lam A, Fang M, Zhou LX, Wu QT, Liao.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Chi-Fang Chin1 Arthur Chun-Chieh Shih2 Kuo-Chin Fan1 3. Department of Computer Science and Information Engineering, National Central University, Chung-Li, Taiwan; Institute of Information Science, Academia Sinica, Taipei, Taiwan; Department of Informatics, Fo Guang Univeristy, Ilan, Taiwan ...

  2. Colubrid Venom Composition: An -Omics Perspective.

    Science.gov (United States)

    Junqueira-de-Azevedo, Inácio L M; Campos, Pollyanna F; Ching, Ana T C; Mackessy, Stephen P

    2016-07-23

    Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes, which actually represent a relatively small proportion of extant species of advanced snakes. Because rear-fanged snakes are a diverse and distinct radiation of the advanced snakes, understanding venom composition among "colubrids" is critical to understanding the evolution of venom among snakes. Here we review the state of knowledge concerning rear-fanged snake venom composition, emphasizing those toxins for which protein or transcript sequences are available. We have also added new transcriptome-based data on venoms of three species of rear-fanged snakes. Based on this compilation, it is apparent that several components, including cysteine-rich secretory proteins (CRiSPs), C-type lectins (CTLs), CTLs-like proteins and snake venom metalloproteinases (SVMPs), are broadly distributed among "colubrid" venoms, while others, notably three-finger toxins (3FTxs), appear nearly restricted to the Colubridae (sensu stricto). Some putative new toxins, such as snake venom matrix metalloproteinases, are in fact present in several colubrid venoms, while others are only transcribed, at lower levels. This work provides insights into the evolution of these toxin classes, but because only a small number of species have been explored, generalizations are still rather limited. It is likely that new venom protein families await discovery, particularly among those species with highly specialized diets.

  3. Study of dielectric and ferroelectric properties of five-layer Aurivillius ...

    Indian Academy of Sciences (India)

    temperature dependent. The Pb2Bi4Ti5O18 ... cations such as piezoelectric sensors operating at high tem- peratures and ... along the c-axis varies depending on whether there is an odd or even ..... Aurivillius B and Fang P H 1962 Phys. Rev.

  4. preparation and characterization of dialdehyde 2, 3-diaminopyridine

    African Journals Online (AJOL)

    User

    be stored in soft (e.g., kidney) and hard tissues (e.g., bone). ... 2003), sweet potato starch (Fang et al., 2004), wheat bran (Farajzadeh and Monji, ... adsorption has been performed to identify the binding property of metal (ii) ions. The maximum.

  5. IFE PsychologIA - Vol 10, No 2 (2002)

    African Journals Online (AJOL)

    What Relates to the Big Five among South African University Students · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Li-fang Zhang, 28-46 ... Vulnerability, Borderline Personality Disorders. Clinical and Therapeutic Issues in Mental Health Using A Cognitive Analytical Model.

  6. Characterization of silver nanoparticles prepared by wet chemical ...

    African Journals Online (AJOL)

    Results: The silver nanoparticles formed were spherical in shape with mean size of 10.3 nm. The ... antibacterial activity against various strains of bacteria. Keywords: Wet ..... Fang J, Zhong C, Mu R. The study of deposited silver particulate ...

  7. Whole genome amplification: Use of advanced isothermal method

    African Journals Online (AJOL)

    Yomi

    2010-12-29

    Dec 29, 2010 ... 1Ph.D. Student, Department of Animal Science, Science and Research Branch, Islamic Azad University(IAU), ... sequence has a large effect on both the denaturation of ..... performance of multiple displacement amplification and OmniPlex ... Dean FB, Hosono S, Fang L, Wu L, Faruqi AF, Bray-Ward P, Sun Z,.

  8. Systemic Struggle between North American Indians and New Age

    DEFF Research Database (Denmark)

    Geertz, Armin W.

    2008-01-01

    Bidraget undersøger den såkaldte hvalfangst-kontrovers, som makah-indianerne i delstaten Washington USA blev udsat for efter at den internationale hvalkommission i 1997 havde givet tilladelse til makah-indianerne til at fange 5 californiske gråhvaler pr. år i fire år. Det var mange miljøorganisat...

  9. Proceedings of the American Journalism Historians' Association Conference (Roanoke, Virginia, October 6-8, 1994). Part II.

    Science.gov (United States)

    American Journalism Historians' Association.

    The second part of the proceedings of this conference of journalism historians contains the following 21 papers: "The First Information Revolution" (Irving Fang); "The 'Andromeda Strain' Phenomenon: Mutating Systems and International Communication Policy" (Eliza Tanner); "Guns or Butter?: Black Press Editorial Policy…

  10. Effect of Malathion on the Microbial Ecology of Activated Sludge

    Science.gov (United States)

    2015-03-26

    L. Long, Y. Fan, J. Gan, J. Fang, and W. Jin, “A review on the detox - ification of organophosphorus compounds by microorganisms,” African Journal of...from pseudomonas diminuta as a model for the detoxication of o-ethyl s-(2-diisopropylaminoethyl) methylphosphonothiolate (vx),” Biochem- ical

  11. Alcohol and retinoids

    DEFF Research Database (Denmark)

    Crabb, D.W.; Pinairs, J.; Hasanadka, R.

    2001-01-01

    , M. Fang, and David W. Crabb; (2) Alcohol, vitamin A, and beta-carotene: Adverse interactions, by M. A. Leo and Charles S. Lieber; (3) Retinoic acid, hepatic stellate cells, and Kupffer cells, by Hidekazu Tsukamoto, K. Motomura, T. Miyahara, and M. Ohata; (4) Retinoid storage and metabolism in liver...

  12. African Journal of Biotechnology - Vol 11, No 41 (2012)

    African Journals Online (AJOL)

    Lenaldo Muniz de Oliveira, Nayra da Silva Negreiros Cardoso, Luzimar Gonzaga .... Ju-Hong Zhang, Jian-Ying Guo, Jing-Yuan Xia, Fang-Hao Wan, 9873-9880 ... Zhu Xiao-yan, Chang Shu-juan, Zhang Ying-jun, Luo Hai-ling, 9894-9905.

  13. Linkage disequilibrium and association mapping of drought ...

    African Journals Online (AJOL)

    sunny t

    2016-11-16

    Nov 16, 2016 ... related to drought tolerance (YongSheng et al., 2009). Among the variety of ... (Li et al., 2013), yield (LiFang et al., 2010) and fibre traits. (Islam et al., 2014). ..... such molecular markers as SSRs (Bertini et al., 2006;. Zhang et al.

  14. JCSC_128_12_1855_1860_SI.doc

    Indian Academy of Sciences (India)

    Choline-based biodegradable ionic liquid catalyst for Mannich-type reaction. PENG HUANa, HU YULINb, XING RONGa, b and FANG DONG*,a, b. a College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, P.R. China. bSchool of Chemistry & Environmental Engineering, Yancheng Teachers University, ...

  15. Reference: 759 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 759 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u18434608i Guan Yue-Feng...s. 2 852-63 18434608 2008 Jun Plant physiology Gao Ju-Fang|Guan Yue-Feng|Huang Xue-Yong|Yang Zhong-Nan|Zhang Hong-Xia|Zhu Jun

  16. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YANG LUO. Articles written in Journal of Genetics. Volume 90 Issue 2 August 2011 pp 339-342 Research Note. Novel vitamin D 1-hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient · Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang ...

  17. Rana nigromaculata

    Indian Academy of Sciences (India)

    ONLINE RESOURCES. Development and characterization of 13 polymorphic microsatellite DNA markers for the pond green frog (Rana nigromaculata). JIE GONG1,2, HONG LAN1,2, SHENG-GUO FANG1,2 and QIU-HONG WAN1,2∗. 1College of Life Sciences, Zhejiang University, Hangzhou 310058, People's Republic of ...

  18. Summary of bi-shRNA/GM-CSF augmented autologous tumor cell immunotherapy (FANG™) in advanced cancer of the liver.

    Science.gov (United States)

    Nemunaitis, John; Barve, Minal; Orr, Douglas; Kuhn, Joseph; Magee, Mitchell; Lamont, Jeffrey; Bedell, Cynthia; Wallraven, Gladice; Pappen, Beena O; Roth, Alyssa; Horvath, Staci; Nemunaitis, Derek; Kumar, Padmasini; Maples, Phillip B; Senzer, Neil

    2014-01-01

    Therapies for advanced hepatocellular carcinoma (HCC) are limited. We carried out a phase I trial of a novel autologous whole-cell tumor cell immunotherapy (FANG™), which incorporates a dual granulocyte macrophage colony-stimulating factor (GM-CSF) expressive/bifunctional small hairpin RNA interference (bi-shRNAi) vector. The bi-shRNAi DNA targets furin, which is a proconvertase of transforming growth factors beta (TGFβ) 1 and 2. Safety, mechanism, immunoeffectiveness, and suggested benefit were previously shown [Senzer et al.: Mol Ther 2012;20:679-689; Senzer et al.: J Vaccines Vaccin 2013;4:209]. We now provide further follow-up of a subset of 8 HCC patients. FANG manufacturing was successful in 7 of 8 attempts (one failure due to insufficient cell yield). Median GM-CSF expression was 144 pg/10(6) cells, TGFβ1 knockdown was 100%, and TGFβ2 knockdown was 93% of the vector-transported cells. Five patients were vaccinated (1 or 2.5×10(7) cells/intradermal injection, 6-11 vaccinations). No FANG toxicity was observed. Three of these patients demonstrated evidence of an immune response to the autologous tumor cell sample. Long-term follow-up demonstrated survival of 319, 729, 784, 931+, and 1,043+ days of the FANG-treated patients. In conclusion, evidence supports further assessment of the FANG immunotherapy in HCC. © 2014 S. Karger AG, Basel.

  19. Ghazala et al., Afr J Tradit Complement Altern Med. (2016) 13(3):54 ...

    African Journals Online (AJOL)

    Key words: Toxicity; Profenofos; esterase activity; issues; fish ... environmental matrices; e.g., water, air, soil and organisms (Fang et al., 2014; Salem et al., ... restricted and was banned in many countries such as European Union countries, Asia, etc. ..... behavioral pattern of fingerling common carp (Cyprinus carpio L., 1758).

  20. African Journal of Biotechnology - Vol 9, No 51 (2010)

    African Journals Online (AJOL)

    Osmotic potential of Zinnia elegans plant material affects the yield and morphology of tracheary elements produced in vitro · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD ... TEXT DOWNLOAD FULL TEXT. C Song, X Cao, KK Nicholas, C Wang, X Li, X Wang, J Fang, 8726-8730 ...

  1. Wave Dragon

    DEFF Research Database (Denmark)

    Kofoed, Jens Peter; Petersen, Anne-Louise S.

    2004-01-01

    Udvikling og produktion af vindmøller har været en af de største danske erhvervssucceser gennem de sidste 10 år. Nu er det næste danske bud på en vedvarende energikilde under udvikling havets bølger skal fanges, og deres energi skal tappes....

  2. Osteogenesis Imperfecta: A Case Report and Review of Literature

    African Journals Online (AJOL)

    OI congenita was found in children whose parents have no traces of the ... fresh air and exercise.[25] Since then ... children,[9,34,35] as well as delay in healing of fractures after osteotomy. .... Castillo H, Samson‑Fang L, American Academy for Cerebral. Palsy and Developmental Medicine Treatment Outcomes. Committee ...

  3. Shang et al., Afr J Tradit Complement Altern Med. (2015) 12(3):125 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    Fang et al., 2011; Yang et al.,2009; Xie et al., 2003) because many marker compounds are not commercially available, especially some characteristic compounds. The purposes of this study were to develop an effective method to extract the overall ...

  4. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 4. CuO/TiO2 nanocrystals grown on graphene as visible-light responsive photocatalytic hybrid materials. Yuan Fang Rijing Wang Guohua Jiang He Jin Yin Wang Xinke Sun Sheng Wang Tao Wang. Volume 35 Issue 4 August 2012 pp 495-499 ...

  5. An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures

    Directory of Open Access Journals (Sweden)

    Edwin O. Nuzum

    2012-10-01

    Full Text Available The Filovirus Animal Non-Clinical Group (FANG is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM, both vaccines and therapeutics. It is co-led by one representative from the Department of Defense (DoD, the first author, and one from the Department of Health and Human Services (HHS, the second author. The FANG membership includes operational level program staff and Subject Matter Experts (SME from performing organizations as well as scientific staff and program managers from DoD and HHS funding and regulatory agencies. Focus areas include animal models, assays, reagents, product manufacture and characterization, and other interagency product development issues that will support Food and Drug Administration (FDA licensure of safe and effective filovirus MCMs. The FANG continues to develop strategies to address broadly applicable and interagency product development challenges relevant to filovirus MCM development. This paper summarizes FANG structure and accomplishments and is meant to heighten community awareness of this government-led collaborative effort.

  6. Working Locally as a True Professional: Case Studies in the Development of Local Curriculum

    Science.gov (United States)

    Sahasewiyon, Kirin

    2004-01-01

    This article investigates the dynamic overall picture concerning the development of local curriculum in Thailand through action research conducted by 27 Thai elementary school teachers in three private schools in Fang District, Chiang Mai Province. This was the teachers' first experience with action research. The article examines the following…

  7. Pesticide Use and Prevention Practices of Tangerine Growers in Northern Thailand

    Science.gov (United States)

    Chalermphol, Juthathip; Shivakoti, Genesh P.

    2009-01-01

    To investigate pesticide use and prevention practices of tangerine growers in Fang district, Chiang Mai province in Northern Thailand. A questionnaire survey of 312 farmers in the study area, in-depth interviews and group discussions. Only 36% of the participants pursued the recommended prevention practices every time they used pesticides.…

  8. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Combination of acupuncture and Chinese medicinal herbs in treating model rats with Polycystic Ovary Syndrome · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. R-J Ma, J Zhou, J-Q Fang, D-H Yang, F Qu. http://dx.doi.org/10.4314/ajtcam.v8i4.3 ...

  9. The identification and syndromic management of snakebite in South ...

    African Journals Online (AJOL)

    The identification of snakebite injury is uncertain, especially in the 40% of patients who do not see the offending snake, unless there are paired fang marks or typical findings of an envenomation syndrome. The differential diagnosis would include a thorn prick, spider bite or scorpion sting. Thorn pricks are not associated with ...

  10. FANS-3D Users Guide (ESTEP Project ER 201031)

    Science.gov (United States)

    2016-08-01

    TECHNICAL DOCUMENT 3293 August 2016 FANS -3D User’s Guide (ESTEP Project ER-201031) Pei-Fang Wang SSC Pacific Hamn-Ching...1.1 THEORY AND NUMERICAL ALGORITHM OF FANS CODE ............................................. 1 2. FANS -3D SOFTWARE DOCUMENTATION AND EXECUTION...5 3. FANS -3D CODE PARALLELIZATION

  11. Does Film Keep Anti-psychiatry Alive?

    DEFF Research Database (Denmark)

    Hansen, Jette Barnholdt

    2015-01-01

    Artiklen præsenterer en retorisk kritik af Milos Formans film Gøgereden med fokus på, hvordan filmen omsætter grundlæggende teser inden for antipsykiatrien til et æstetisk sprog, der er kendetegnet ved nogle virkningsfulde metaforer som fx "fængsel" og "fange". Artiklen plæderer afslutningsvis fo...

  12. Asthma in patients with psoriasis

    DEFF Research Database (Denmark)

    Lønnberg, A S; Skov, L; Skytthe, A

    2015-01-01

    We read with interest the report by Fang and colleagues of the relationship between psoriasis and asthma in a large retrospective case-control study from Taiwan [1]. The study found a 1.38-fold increased risk of asthma among patients with psoriasis, and with an increasing risk according to higher...

  13. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Molecular cytogenetic identification of a wheat– Thinopyrum ponticum translocation line resistant to powdery mildew · FANG HE YINGUANG BAO XIAOLEI QI YINGXUE MA XINGFENG LI HONGGANG WANG · More Details Abstract Fulltext PDF. Thinopyrum ponticum (2n = 70) serves as a valuable gene pool for wheat ...

  14. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Jain Fang Gui. Articles written in Journal of Genetics. Volume 89 Issue 2 August 2010 pp 163-171 Research Article. Chromosomal localization of rDNA genes and genomic organization of 5S rDNA in Oreochromis mossambicus, O. urolepis hornorum and their hybrid · Hua Ping Zhu Mai ...

  15. Browse Title Index

    African Journals Online (AJOL)

    Items 151 - 200 of 11090 ... C Ko, J Kung, R Mc Donald. Vol 14, No 25 (2015), In vitro microtuberization of Black Zira (Bunium persicum Boiss.) .... Sujing Fu, Hengkang Hu, Qixiang Zhang, Yanming Fang, Zhengxiong Shen, Yuqiong Gao. Vol 7, No 3 (2008), In vitro propagation of miracle berry (Synsepalum dulcificuDaniel) ...

  16. A review on malaria eradication: what hope for Nigeria? | Amadi ...

    African Journals Online (AJOL)

    Malaria and its transmitting vectors are household names. Malaria which helped Africa from the venomous fangs of colonialism has turned to be the bane of development in tropical countries including Nigeria. The factors which promote prevalence of the disease and its transmission dynamics are well discussed in this ...

  17. Cooperation for Better Inhibiting.

    Science.gov (United States)

    Novoa, Eva Maria; Ribas de Pouplana, Lluís

    2015-06-18

    Cladosporin is an antimalarial drug that acts as an ATP-mimetic to selectively inhibit Plasmodium lysyl-tRNA synthetase. Using multiple crystal structures, Fang et al. (2015) reveal in this issue of Chemistry & Biology the fascinating mechanism responsible for cladosporin selectivity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Genetic diversity based on SSR markers in maize (Zea mays L.)

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 87; Issue 3. Genetic diversity based on SSR markers in maize (Zea mays L.) landraces from Wuling mountain region in China. Yao Qi-Lun Fang Ping Kang Ke-Cheng Pan Guang-Tang. Research Note Volume 87 Issue 3 December 2008 pp 287-291 ...

  19. An efficient somatic embryogenesis based plant regeneration from ...

    African Journals Online (AJOL)

    ajl yemi

    2010-03-05

    Mar 5, 2010 ... Fang Yuan, Quan Wang, Qifang Pan, Guofeng Wang, Jingya Zhao, Yuesheng Tian and. Kexuan Tang*. Plant Biotechnology Research Center, School of Agriculture and Biology, Fudan-SJTU-Nottingham Plant Biotechnology. R&D Center, Shanghai Jiao Tong University, Shanghai 200240, P. R. China.

  20. Identifying the Last Planner System

    DEFF Research Database (Denmark)

    Brinch Jensen, Kenneth

    Ledelsesteknologier såsom Balanced Scorecard, Six Sigma og Activity Based Costing må fremtræde som konkrete, stabile, funktionelle og homogene løsninger, hvis de skal kunne fange både interesse og finansiering i forretningsverdenen. Studier af disse ledelsesteknologiers møde med...

  1. Follow-up study of a pregnant woman 16 years after exposure in the Xinzhou radiation accident

    International Nuclear Information System (INIS)

    Zhang Zhaohui; Liang Li; Zhang Shu-lan; Jia Tingzhen; Liu Qingjie; Ma Liwen; Su Xu; Liu Ying; Chen Sen; Qing Bin; Cao Baoshan; Xiao Yu; Ying Wenchen; Zhang Yu; Wang Wenxue; Wang Zuoyuan

    2011-01-01

    To investigate the late effects of radiation on child-bearing women, a follow-up study was performed on a 39-year-old survivor 16 years after a 60 Co radiation accident. The woman, Fang, was 19 weeks pregnant at the time of exposure. Physical examinations, a full range of clinical laboratory and imaging tests, as well as cytogenetic analyses were conducted to evaluate Fang's current health conditions. Fang shows the appearance of premature ageing and has a decreased menstrual period. Laboratory studies and imaging tests suggest nodular goitre disease and osteoporosis. Otherwise, no apparent abnormalities were found in the major organs. No malignant tumours were detected by either tumour markers or imaging tests. However, the existence of chromosome aberrations warrants long-term follow-up for tumour incidence in the future. Fang became pregnant 8 years after the accident, but suffered a miscarriage due to the death of the foetus at 6 months into the pregnancy. In conclusion, our findings suggest that the intrauterine death of the foetus might be associated with the previous exposure. There is no evidence of malignant tumours as of the date of the follow-up study. Non-cancerous diseases, i.e. thyroid disease and osteoporosis, which may be related to radiation exposure, are the major manifestations of the long-term effects of the accident. (note)

  2. Evolution of an arsenal: structural and functional diversification of the venom system in the advanced snakes (Caenophidia).

    Science.gov (United States)

    Fry, Bryan G; Scheib, Holger; van der Weerd, Louise; Young, Bruce; McNaughtan, Judith; Ramjan, S F Ryan; Vidal, Nicolas; Poelmann, Robert E; Norman, Janette A

    2008-02-01

    Venom is a key innovation underlying the evolution of advanced snakes (Caenophidia). Despite this, very little is known about venom system structural diversification, toxin recruitment event timings, or toxin molecular evolution. A multidisciplinary approach was used to examine the diversification of the venom system and associated toxins across the full range of the approximately 100 million-year-old advanced snake clade with a particular emphasis upon families that have not secondarily evolved a front-fanged venom system ( approximately 80% of the 2500 species). Analysis of cDNA libraries revealed complex venom transcriptomes containing multiple toxin types including three finger toxins, cobra venom factor, cysteine-rich secretory protein, hyaluronidase, kallikrein, kunitz, lectin, matrix metalloprotease, phospholipase A(2), snake venom metalloprotease/a disintegrin and metalloprotease, and waprin. High levels of sequence diversity were observed, including mutations in structural and functional residues, changes in cysteine spacing, and major deletions/truncations. Morphological analysis comprising gross dissection, histology, and magnetic resonance imaging also demonstrated extensive modification of the venom system architecture in non-front-fanged snakes in contrast to the conserved structure of the venom system within the independently evolved front-fanged elapid or viperid snakes. Further, a reduction in the size and complexity of the venom system was observed in species in which constriction has been secondarily evolved as the preferred method of prey capture or dietary preference has switched from live prey to eggs or to slugs/snails. Investigation of the timing of toxin recruitment events across the entire advanced snake radiation indicates that the evolution of advanced venom systems in three front-fanged lineages is associated with recruitment of new toxin types or explosive diversification of existing toxin types. These results support the role of venom

  3. Comparison of long-term clinical outcome between patients with chronic versus acute type B aortic dissection treated by implantation of a stent graft: a single-center report

    Directory of Open Access Journals (Sweden)

    Chen SL

    2013-04-01

    Full Text Available Shao-Liang Chen, Jian-Cheng Zhu, Xiao-Bo Li, Fei Ye, Jun-Jie Zhang, Zhi-Zhong Liu, Nai-Liang Tian, Song Lin, Cheng-Yu Lv Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China Background: Stent grafting for treatment of type B aortic dissection has been extensively used. However, the difference in the long-term clinical outcome between patients with chronic versus acute type B aortic dissection remains unknown. This study aimed to analyze the difference in long-term clinical outcome after endovascular repair for patients with chronic (93% complete false-lumen thrombosis. Untreated tear and type I endoleak were predictors of clinical events during follow-up. Conclusion: Comparable long-term clinical results were achieved in patients with chronic or acute type B aortic dissection after implantation of a stent graft. Keywords: aortic dissection, endovascular repair, procedure-related events, propensity score matching

  4. Hematological observations on two cases of acute radiation syndrome

    International Nuclear Information System (INIS)

    Jiang Benrong; Wang Guilin; Huang Shimin

    1990-01-01

    The hematological changes of two cases of acute radiation syndrome were observed. The physical doses of patients Liang and Yan were 3.5 Gy and 2.6 Gy respectively. According to the changes in WBC and platelet counts and the absolute count of lymphocytes and in comparison with the hematological data of the victims of Y-12 accident in USA in 1958 and those of previous accidents in China, Liang suffered from a moderate or moderate to severe degree, and Yan suffered from a moderate or moderate mild degree of hemopoietic form of acute radiation syndrome. This estimation was consistent with their clinical course and physical doses. Some blood cells appeared in the cytoplasm of megakaryocytes in bone marrow smears of those two cases. The mechanism of this phenomenon is discussed and its clinical significance remains to be studied

  5. The Body As Cogito: A Certain Contemporary Film In The Light of Merleau-Ponty

    Directory of Open Access Journals (Sweden)

    Julio Bezerra

    2014-04-01

    Full Text Available Contemporary film is displaying a kind of "transnational new wave" that seems unique since the mid-60s. Filmmakers as diverse as Tsai Ming-Liang, Karim Aïnouz, and Apichatpong Weerasethakul, show a similar sensitivity towards the values of the world and of the cinema. What brings the work of these directors together is the taste for a realism more focused on the phenomenon of experience, on issues of skin and surface, and a different look at the body. Our hypothesis is that the phenomenology of Merleau-Ponty provides us with valuable tools to broaden the debate. The discussion will be carried out by an analysis of the work of Tsai Ming-Liang, Apichatpong Weerasethakul and Karim Aïnouz.

  6. Failure data analysis of the SuperHILAC radio frequency subsystem

    International Nuclear Information System (INIS)

    Chang, M.K.

    1978-12-01

    This report is a continuation of an earlier report by Liang with emphasis now on the Radio Frequency subsystem and its components, using current and improved data. It was stated in Liang's report that improvement in overall SuperHILAC availability, which must be very high for medical purposes, is best made by improving subsystems that are needed in all modes of operation. Two such subsystems were Radio Frequency (RF) and Other, with relatively low availabilities of .96 and .93 respectively. Since subsystem Other is not well defined, the RF became the object of this investigation. It was hoped that the components of the RF would show properties that were obscured at the higher level. The analytic procedure of this report is essentially identical to that in the earlier report, except that an operating period analysis is added

  7. Update of research on the role of EZH2 in cancer progression

    Directory of Open Access Journals (Sweden)

    Shen L

    2013-04-01

    Full Text Available Liang Shen,1 Jing Cui,2 Shumei Liang,3 Yingxin Pang,1 Peishu Liu11Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, 2Department of Oral and Maxillofacial Surgery, Jinan Stomatologic Hospital, 3Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, People’s Republic of ChinaAbstract: Accumulating evidence shows that enhancer of zeste homolog 2 (E2H2 is upregulated in a broad range of cancer types, such as breast cancer, prostate cancer, ovarian cancer, and colon cancer. Therefore, inhibiting EZH2 expression may be a promising strategy for anticancer therapy. This review focuses on the current understanding of the mechanisms underlying EZH2 regulation that are involved in cancer progression. Also, it introduces two EZH2 inhibitors that target EZH2 and could be potentially applied in the treatment of cancer in the future.Keywords: EZH2, PRC2, cancer

  8. The effectiveness of a combined exercise intervention on physical fitness factors related to falls in community-dwelling older adults

    OpenAIRE

    Zhuang J; Huang L; Wu Y; Zhang Y

    2014-01-01

    Jie Zhuang,1,* Liang Huang,1,2,* Yanqiang Wu,3 Yanxin Zhang2 1School of Kinesiology, Shanghai University of Sport, Shanghai, People's Republic of China; 2Department of Sport and Exercise Science, The University of Auckland, Auckland, New Zealand; 3Shanghai Municipal Center for Students' Physical Fitness and Health Surveillance, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: This study aimed to evaluate the effectiveness ...

  9. Statistical analysis on hollow and core-shell structured vanadium oxide microspheres as cathode materials for Lithium ion batteries

    Directory of Open Access Journals (Sweden)

    Xing Liang

    2018-06-01

    Full Text Available In this data, the statistical analyses of vanadium oxide microspheres cathode materials are presented for the research article entitled “Statistical analyses on hollow and core-shell structured vanadium oxides microspheres as cathode materials for Lithium ion batteries” (Liang et al., 2017 [1]. This article shows the statistical analyses on N2 adsorption-desorption isotherm and morphology vanadium oxide microspheres as cathode materials for LIBs. Keywords: Adsorption-desorption isotherm, Pore size distribution, SEM images, TEM images

  10. Dirac cone protected by non-symmorphic symmetry and three-dimensional Dirac line node in ZrSiS

    OpenAIRE

    Schoop, Leslie M.; Ali, Mazhar N.; Straßer, Carola; Topp, Andreas; Varykhalov, Andrei; Marchenko, Dmitry; Duppel, Viola; Parkin, Stuart S. P.; Lotsch, Bettina V.; Ast, Christian R.

    2016-01-01

    Materials harboring exotic quasiparticles, such as Dirac and Weyl fermions\\cite{xu2015discovery,borisenko2015time,weng2015weyl,xu2015observation}, have garnered much attention from the physics and material science communities. These fermions are massless and, in some materials, have shown exceptional physical properties such as ultrahigh mobility and extremely large magnetoresistances \\cite{liang2015ultrahigh,ali2014large,du2015unsaturated,shekhar2015large}. Recently, new materials have been ...

  11. Facies associations, depositional environments and stratigraphic framework of the Early Miocene-Pleistocene successions of the Mukah-Balingian Area, Sarawak, Malaysia

    Science.gov (United States)

    Murtaza, Muhammad; Rahman, Abdul Hadi Abdul; Sum, Chow Weng; Konjing, Zainey

    2018-02-01

    Thirty-five stratigraphic section exposed along the Mukah-Selangau road in the Mukah-Balingian area have been studied. Sedimentological and palynological data have been integrated to gain a better insight into the depositional architecture of the area. Broadly, the Mukah-Balingian area is dominated by fluvial, floodplain and estuarine related coal-bearing deposits. The Balingian, Begrih and Liang formations have been described and interpreted in terms of seven facies association. These are: FA1 - Fluvial-dominated channel facies association; FA2 - Tide-influenced channel facies association; FA3 - Tide-dominated channel facies association; FA4 - Floodplain facies association; FA5 - Estuarine central basin-mud flats facies association; FA6 - Tidal flat facies association and FA7 - Coastal swamps and marshes facies association. The Balingian Formation is characterised by the transgressive phase in the base, followed by a regressive phase in the upper part. On the basis of the occurrence of Florscheutzia trilobata with Florscheutzia levipoli, the Early to Middle Miocene age has been assigned to the Balingian Formation. The distinct facies pattern and foraminifera species found from the samples taken from the Begrih outcrop imply deposition in the intertidal flats having pronounced fluvio-tidal interactions along the paleo-margin. Foraminiferal data combined with the pronounced occurrence of Stenochlaena laurifolia suggest at least the Late Miocene age for the Begrih Formation. The internal stratigraphic architecture of the Liang Formation is a function of a combination of sea level, stable tectonic and autogenic control. Based on stratigraphic position, the Middle Pliocene to Pleistocene age for the Liang Formation is probable. The Balingian, Begrih and Liang formations display deposits of multiple regressive-transgressive cycles while the sediments were derived from the uplifted Penian high and Rajang group.

  12. Sm , Bi phosphors with high efficiency white-light-emittin

    Indian Academy of Sciences (India)

    2017-08-29

    Aug 29, 2017 ... Therefore, researches on high efficiency red phos- phors are very important. So far ..... ing concentration and reached a maximum at y = 8 mol%. A .... [10] Xue L P, Wang Y J, Lv P W, Chen D G, Lin Z, Liang J K et al. 2009 Crystal ... [28] Liu J, Xu B, Song C, Luo H, Zou X, Han L et al 2012 Cryst-. EngComm.

  13. Effects of insulin analogs and glucagon-like peptide-1 receptor agonists on proliferation and cellular energy metabolism in papillary thyroid cancer

    OpenAIRE

    He, Liang; Zhang, Siliang; Zhang, Xiaowen; Liu, Rui; Guan, Haixia; Zhang, Hao

    2017-01-01

    Liang He,1,* Siliang Zhang,2,* Xiaowen Zhang,3 Rui Liu,2 Haixia Guan,2 Hao Zhang1 1Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning, 2Department of Endocrinology and Metabolism, The Endocrine Institute and The Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, 3Department of Endocrinology and Metabolism, Drum Tower Hospital Affiliated to Nanjing University Medical Schoo...

  14. Supplementary data: Variation in the PTEN-induced putative kinase ...

    Indian Academy of Sciences (India)

    Variation in the PTEN-induced putative kinase 1 gene associated with the increase risk of type 2 diabetes in northern Chinese. Yanchun Qu, Liang Sun, Ze Yang and Ruifa Han. J. Genet. 90, 125–128. Table 1. Clinical characteristics of cases and controls. Phenotype. T2DM. Controls. P value. Age (years). 49.5 ± 11.1. 50.4 ± ...

  15. Analysis of a SCADA System Anomaly Detection Model Based on Information Entropy

    Science.gov (United States)

    2014-03-27

    Gerard, 2005:3) The NTSB report lists alarm management as one of the top five areas for improvement in pipeline SCADA systems (Gerard, 2005:1...Zhang, Qin, Wang, and Liang for leak detection in a SCADA -run pipeline system. A concept derived from information theory improved leak detection...System for West Products Pipeline . Journal of Loss Prevention in the Process Industries, 22(6), 981-989. Zhu, B., & Sastry, S. (2010). SCADA

  16. Raman spectroscopy, a non-invasive mesurement technique for the detection of counterfeit medicines

    OpenAIRE

    Marta, Teresa Rita Pitorra

    2016-01-01

    Tese de mestrado, Engenharia Farmacêutica, Universidade de Lisboa, Faculdade de Farmácia, 2016 Perhaps no greater challenge exists for public health, patient safety, and shared global health security, than fake, falsified, fraudulent or poor quality unregulated medicines - also commonly known as “counterfeit medicines” - now endemic in the global drug supply chain (Tim K Mackey & Liang, 2013). Counterfeit medicines pose a serious risk to public health around the world. It is low- and mi...

  17. Improving Deployment-Related Primary Care Provider Assessments of PTSD and Mental Health Conditions

    Science.gov (United States)

    2013-10-01

    Meehl, P. E. (1989). Clinical versus actuarial judgment. Science , 243. 1668- 1674. Diggle, P., Heagerty, P., Liang, K.-Y., & Zeger, S. L. (2002...review. Bmc Health Services Research, 8, 10. doi: 17910.1186/1472-6963-8-179 Cohen, J. (1988). Statistical power analysis for the behavioral sciences ...of information they are presented with. Meehl (1954) was the first to make a distinction between clinical and actuarial (also known as statistical

  18. On Dataless Hierarchical Text Classification (Author’s Manuscript)

    Science.gov (United States)

    2014-07-27

    compound talk.politics.mideast politics mideast israel arab jews jewish muslim talk.politics.misc politics gay homosexual sexual alt.atheism atheism...tion in NLP tasks; it was further used in several NLP works, such as by Liang (2005), to measure words’ distributional similarity. This method...embedding trained by neural networks has been used widely in the NLP community and has become a hot trend recently. In this pa- per, we test the suitability

  19. The ability of NT-proBNP to detect chronic heart failure and predict all-cause mortality is higher in elderly Chinese coronary artery disease patients with chronic kidney disease

    OpenAIRE

    Fu, Shihui; Yi,Shuangyan; Liu,Yuan; Zhu,Bing; Wang,Liang; Tiehui Xiao,; Bai,Yongyi; Ye,Ping; Luo,Leiming

    2013-01-01

    Shihui Fu, Leiming Luo, Ping Ye, Shuangyan Yi, Yuan Liu, Bing Zhu, Liang Wang, Tiehui Xiao, Yongyi Bai Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China Objective: To analyze the relationship between N-terminal pro-brain natriuretic peptide (NT-proBNP) and renal function, and compare the ability and cut-off thresholds of NT-proBNP to detect chronic heart failure (CHF) and predict mortality in elderly Chinese coronary artery disease ...

  20. A Partnership Training Program in Breast Cancer Research Using Molecular Imaging Techniques

    Science.gov (United States)

    2007-07-01

    vivo cancer targeting and imaging with semiconductor quantum dots. Dr. Dnyanesh N. Tipre, Wednesday, Sept. 6, 2006 2. Synthesis , Surface and Colloidal...Materials: Synthesis and Modification of Functional Polymers and Application to Biomineralization. Dr. Tongxin Wang, University of Pennsylvania, 3/1/07 II.2... nitrosoureas (Journal of Clinical Investigation, in Review) [*: Equal contribution] 28. Liang, X.J. and Park, J.K. Inhibition of stathmin enhances CCNU

  1. An Investigation into the Level of Compensation in the Aerospace Industry

    Science.gov (United States)

    1983-06-01

    which the observations that have been made may be more fully understood. W. K. Liang in Toward an Institutional Theory of Wage [Ref. 45] discussed...commodity was considered obsolete, and in his work, Toward an Institutional Theory of Wage, he went on to develop an institutional theory of wage, based... Institutional Theory of Wage, New York, 1974. 46. Ibid. , pp. 1-2. 47. Ibid., p. 10. 48. Ibid. , p. 20. 49. Ibid. , pp. 44-45. 50. Ibid. , pp. 26

  2. The γ-gliadin-like γ-prolamin genes in the tribe Triticeae

    Indian Academy of Sciences (India)

    Supplementary data: The γ-gliadin-like γ-prolamin genes in the tribe Triticeae. Peng-Fei Qi, Cheng-Xing Le, Zhao Wang, Yu-Bin Liu, Qing Chen, Zhen-Zhen Wei, Bin-Jie Xu, Zheng-Yuan Wei,. Shou-Fen Dai, Yu-Ming Wei and You-Liang Zheng. J. Genet. 93, 35–41. Table 1. The γ-prolamin genes of diploid Triticeae species.

  3. Preparing to Predict: The Second Autonomous Ocean Sampling Network (AOSN-II) Experiment in the Monterey Bay

    Science.gov (United States)

    2008-06-06

    MBARI buoy M2, profiling to 250 m depth (Figure 1). Instruments on board included a CTD, fluorometer, oxygen and nitrate sensors, bioluminescence, and...dimensional multiscale ocean variability: Massachusetts Bay. Journal of Marine Systems, Special issue on “Three-dimensional ocean circulation: Lagrangian...Oceanography”, T. Paluszkiewicz and S. Harper, Eds., Vol. 19, 1, 172-183. Liang, X.S. and Anderson, D.G.M. (2007) Multiscale Window Transform, SIAM J

  4. Transcriptional Regulation by KLF6, A Novel Tumor Suppressor Gene in Prostate Cancer, Through Interaction with HATS and HDACS

    Science.gov (United States)

    2006-03-01

    Kimmelman1, Rui F Qiao1, Goutham Narla2, Asoka Banno1, Nelson Lau3, Paula D Bos1, Nelson Nuñez Rodriguez1, Bertrand C Liang4, Abhijit Guha3, John A...Shen Yao, 1 Asoka Banno, 3 Eldad Hod, 1 Helen L. Reeves, 1 Rui F. Qiao, 3 Olga Camacho-Vanegas, 2 Alice Levine, 1 Alexander Kirschenbaum, 1,4 Andrew M

  5. Quantitative trait loci for rice yield-related traits using recombinant ...

    Indian Academy of Sciences (India)

    2011-08-19

    Aug 19, 2011 ... lated by map-based cloning strategy (Ashikari et al. 2005). ... 2000; Kojima et al. 2002; Doi et al. 2004). ... and PH but also on rice yield (Xue et al. 2008; Yan et al. ..... Cho Y. C., Suh J. P., Choi I. S., Hong H. C., Baek M. K., Kang K. H. et al. .... Yan C. J., Liang G. H., Chen F., Li X., Tang S. Z., Yi C. D. et al.

  6. Can we compare SMS marketing to traditional marketing communications?

    OpenAIRE

    Roozen, Irene; Genin, Emile

    2008-01-01

    Nowadays most companies acknowledge the importance of SMS marketing in reaching and interacting with their customers (Kavassalis et al. 2003; Dickinger et al. 2004; Tsang, Ho & Liang 2004; Sharl, Dickinger & Murphy 2005; Muk 2007). However, there is much discussion in the press regarding the effectiveness when it comes to SMS marketing. Are customers willing to accept, reading and using SMS messages: how effective is SMS marketing compared to traditional marketing communications? The goal of ...

  7. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Zdeněk P Bažant. Articles written in Sadhana. Volume 37 Issue 1 February 2012 pp 17-31. Size effect on strength and lifetime probability distributions of quasibrittle structures · Zdeněk P Bažant Jia-Liang Le · More Details Abstract Fulltext PDF. Engineering structures such as aircraft, bridges, ...

  8. 18 GHz SZ Measurements of the Bullet Cluster Siddharth S. Malu ...

    Indian Academy of Sciences (India)

    1E0657-56, known as the 'Bullet cluster', is one of the hottest known clusters. It is a cluster collision/merger event at z ∼0.296, with the larger, westward cluster being ∼10 times the mass of the smaller 'bullet'. It is known to have a strong radio halo (Liang et al. 2000), and the Sunyaev–Zel'dovich effect (Andreani et al. 1999;.

  9. Thermodynamic aspects of information transfer in complex dynamical systems

    Science.gov (United States)

    Cafaro, Carlo; Ali, Sean Alan; Giffin, Adom

    2016-02-01

    From the Horowitz-Esposito stochastic thermodynamical description of information flows in dynamical systems [J. M. Horowitz and M. Esposito, Phys. Rev. X 4, 031015 (2014), 10.1103/PhysRevX.4.031015], it is known that while the second law of thermodynamics is satisfied by a joint system, the entropic balance for the subsystems is adjusted by a term related to the mutual information exchange rate between the two subsystems. In this article, we present a quantitative discussion of the conceptual link between the Horowitz-Esposito analysis and the Liang-Kleeman work on information transfer between dynamical system components [X. S. Liang and R. Kleeman, Phys. Rev. Lett. 95, 244101 (2005), 10.1103/PhysRevLett.95.244101]. In particular, the entropic balance arguments employed in the two approaches are compared. Notwithstanding all differences between the two formalisms, our work strengthens the Liang-Kleeman heuristic balance reasoning by showing its formal analogy with the recent Horowitz-Esposito thermodynamic balance arguments.

  10. Early modern human lithic technology from Jerimalai, East Timor.

    Science.gov (United States)

    Marwick, Ben; Clarkson, Chris; O'Connor, Sue; Collins, Sophie

    2016-12-01

    Jerimalai is a rock shelter in East Timor with cultural remains dated to 42,000 years ago, making it one of the oldest known sites of modern human activity in island Southeast Asia. It has special global significance for its record of early pelagic fishing and ancient shell fish hooks. It is also of regional significance for its early occupation and comparatively large assemblage of Pleistocene stone artefacts. Three major findings arise from our study of the stone artefacts. First, there is little change in lithic technology over the 42,000 year sequence, with the most noticeable change being the addition of new artefact types and raw materials in the mid-Holocene. Second, the assemblage is dominated by small chert cores and implements rather than pebble tools and choppers, a pattern we argue pattern, we argue, that is common in island SE Asian sites as opposed to mainland SE Asian sites. Third, the Jerimalai assemblage bears a striking resemblance to the assemblage from Liang Bua, argued by the Liang Bua excavation team to be associated with Homo floresiensis. We argue that the near proximity of these two islands along the Indonesian island chain (c.100 km apart), the long antiquity of modern human occupation in the region (as documented at Jerimalai), and the strong resemblance of distinctive flake stone technologies seen at both sites, raises the intriguing possibility that both the Liang Bua and Jerimalai assemblages were created by modern humans. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. PREFACE: 14th International Conference on Metrology and Properties of Engineering Surfaces (Met & Props 2013)

    Science.gov (United States)

    Fu, Wei-En

    2014-03-01

    of Japan, Japan) Dr Heui-Jae Pahk (SNU Precision Co. Ltd., Korea) Professor Jiu-Bin Tan (Harbin Institute of Technology, China) Ms. Siew-Leng Tan (National Metrology Centre (NMC/A*STAR), Singapore) Mr. A. Tonmueanwai (National Institute of Metrology, Thailand (NIMT), Thailand) Professor Kazuhisa Yanagi (Nagaoka University, Japan) Local Organizing Committee Dr Victor Tzeng-Yow Lin (Center for Measurement Standards, ITRI, Taiwan) Professor Kuang-Chao Fan (National Taiwan University, Taiwan) Professor Jen-Fin Lin (ASME Fellow, National Cheng Kung University, Taiwan) Professor Chao-Chang Chen(National Taiwan University of Science and Technology, Taiwan) Professor Shih-Chieh Lin (National Tsing Hua University, Taiwan) Professor Liang-Chia Chen (National Taiwan University, Taiwan) Professor Fang-Jung Shiou (National Taiwan University of Science and Technology, Taiwan) Professor Chun-Hui Chung (National Taiwan University of Science and Technology, Taiwan) Professor Pin-Chuan Chen (National Taiwan University of Science and Technology, Taiwan) Dr Wen-En Fu (Center for Measurement Standards, ITRI, Taiwan)

  12. Morphological characterization of the venom apparatus in the wolf spider Lycosa singoriensis (Laxmann, 1770

    Directory of Open Access Journals (Sweden)

    N Yigit

    2009-01-01

    Full Text Available The wolf spider Lycosa singoriensis (Laxmann, 1770 (Lycosidae: Araneae is distributed throughout central and eastern Europe, including Russia, Kazakhistan and Turkey. This study describes the venom apparatus morphology of L. singoriensis through scanning electron microscopy (SEM. Its structure follows the general architecture observed in other spiders. Generally, a venom apparatus is composed by a pair of venom glands and chelicerae. L. singoriensis chelicerae are robust and consist of a stout basis and a movable apical segment (fang. The fang rests in a groove on the basal segment that is covered by different types of hair. L. singoriensis venom glands present equal size and measure about 4 mm in length. Each gland is enclosed by irregular muscular layers.

  13. Tratamiento de aguas residuales mixtas

    OpenAIRE

    Gamonal Repiso, Pablo

    2011-01-01

    El present projecte presenta el disseny d´una estació depuradora d´aigües residuals (EDAR) situada a Sabadell i que dóna servei a 186.160 habitants equivalents, definint la matèria primera de l´estació (aigua residual). els processos de tractament d´aigües y fangs (pretractament, tractament priamri, tractament segundari y tractament de fangs). L´objectiu de l´EDAR no es potabilitzar l´aigua, sinó que es disminuir al màxim els contaminants per a que el medi ambient i l´ecosistema receptors ...

  14. Barro y matemáticas: 9 sucesiones y una escala

    OpenAIRE

    Lluis, Josep; Pol, Catalina; Triay, Maria

    2009-01-01

    El objeto de este artículo es presentar el cartel didáctico que relaciona matemáticas y cerámica titulado La successió del fang (La sucesión del barro) y las actividades que entorno a él se han realizado en el marco de la Fira del Fang (Feria del Barro) que organiza el Ayuntamiento de Marratxí (Mallorca). En esta ocasión, el cartel didáctico ha corrido a cargo de la Societat Balear de Matemàtiques SBM-XEIX. El público escolar al que va dirigido abarca principalmente edades desde 4 a 12 años....

  15. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... You-Dong Hu. Articles written in Journal of Astrophysics and Astronomy. Volume 35 Issue 3 September 2014 pp 423-427 Part V: Black Holes (or Binary Black Holes) in Blazars. Joint Spectral Analysis for Early Bright X-ray Flares of -Ray Bursts with Swift BAT and XRT Data · Fang-Kun Peng You-Dong Hu ...

  16. Chinese Function Manager of 2006 Partenariat Comments on the Selection Principle for Chinese Enterprises

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

      Fang Lei, EU-China Partenariat 2006Function Manager for Chinese Host Companies, worked together with Mr. Richard Morgan, EU Project Expert,Mr. Han Meiqing, Chinese Project Expert in the primary selection of Chinese enterprises.In reply to the strong request of the relevant governmental institutions, CCPIT and enterprises, he gave the following introductions about the details of selection.……

  17. Purification and in vitro antioxidant activities of tellurium-containing phycobiliproteins from tellurium-enriched Spirulina platensis

    OpenAIRE

    Chen, Tianfeng; Yang,Fang; Wong,Ka-Hing; Yang,Yufeng; Li,Xiaoling; Jiang,Jie; Wu,Hualian; Zheng,Wenjie

    2014-01-01

    Fang Yang,1 Ka-Hing Wong,2 Yufeng Yang,3 Xiaoling Li,1 Jie Jiang,1 Wenjie Zheng,1 Hualian Wu,1 Tianfeng Chen1 1Department of Chemistry, Jinan University, Guangzhou, People’s Republic of China; 2Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, People’s Republic of China; 3Institute of Hydrobiology, College of Life Science and Technology, Jinan University, Guangzhou, People’s Republic of China Abstract: Tellu...

  18. China Report: Political, Sociological and Military Affairs.

    Science.gov (United States)

    1983-03-18

    Production Brigade of Guangbao Commune in raising chickens and rabbits in a big way. We must mobilize the commune member house- holds to utilize...The state and the commune, production brigades, and production teams operate fish farms, some of which raise fry . Why not go ahead with raising fish...Wei Xinyi, Huang Yu, Yang Jike, Guo Tixiang, Meng Fulin, Hu Tan, Zhu Nong, Fang Shiliang, Wang Zenong, Pan Ezhang, Liu Zhengwen, Chen Tianren, Ma

  19. From Subsistence to Commercial Hunting: Technical Shift in Cynegetic Practices Among Southern Cameroon Forest Dwellers During the 20th Century

    Directory of Open Access Journals (Sweden)

    Edmond Dounias

    2016-03-01

    Full Text Available Tropical rainforest dwellers, who are currently engaged in bushmeat trade, used to track game for their own subsistence. We investigate the technical evolution over the past century of bushmeat procurement by the Fang, a group of southern Cameroon forest dwellers who are renowned for their extensive cynegetic expertise. This investigation consists of a diachronic approach to assess Fang hunting and trapping technology by comparing firsthand data on bushmeat procurement collected in the early 1990s with detailed descriptions recorded in the early 1900s among the same populations by the German anthropologist Günter Tessmann. Other archive sources bequeathed by explorers in the twilight of the 19th century are also exploited. The comparison conveys a more dynamic view of hunting practices following the greater involvement of the Fang hunters in the bushmeat trade. Historical sources remind us that projectile weapons were initially destined for warfare and that trapping, mobilizing a vast panel of modalities, was the prominent means to catch game for domestic consumption. Net hunting and crossbow hunting, which used to be typical Fang activities, are now exclusively conducted by Pygmies; spear hunting with hounds has become anecdotal. If a large range of trap mechanisms is still functional, effort is now focused on snares, elicited by the banalization of twisted wire cable. The legacy of other remaining models is left to children who carry out a didactic form of garden trapping. The major detrimental change is the use of firearms, which were initially adopted as a warfare prestige attribute before becoming the backbone instrument of bushmeat depletion. Revisiting the past provides useful lessons for improving current hunting management, through the promotion of garden hunting and wildlife farming, and the revitalization of a collective and cultural art of hunting as an alternative to indiscriminate overhunting by neophyte and increasingly

  20. Advanced MRI in Acute Military TBI

    Science.gov (United States)

    2015-11-01

    N Engl J Med 358:453-463. 413 10. Kennedy, J.E., Cullen , M.A., Amador, R.R., Huey, J.C., and Leal, F.O. 2010. Symptoms in military service members...Neurosurg Psychiatry 77:1180-1184. 502 44. Dempsey, K.E., Dorlac, W.C., Martin, K., Fang, R., Fox, C., Bennett, B., Williams , K., and Flaherty, S. 2009. 503

  1. Manden, der så englen

    DEFF Research Database (Denmark)

    Hansen, Kim Toft

    2008-01-01

    Man skal helst se Andrei Tarkovskys film mindst to gange: En gang for at fange de enestående fortællinger, og en gang for at se på de fantastiske billeder. Uden sidestykke formåede Tarkovsky at koble sine fortællinger til en visuel repræsentation, der giver noget nær fuldendte værker. I anledning...

  2. Trends in Prevalence, Awareness, Treatment, and Control of Diabetes Mellitus in Mainland China from 1979 to 2012

    OpenAIRE

    Li, Min-zhi; Su, Li; Liang, Bao-yun; Tan, Jin-jing; Chen, Qing; Long, Jian-xiong; Xie, Juan-juan; Wu, Guang-liang; Yan, Yan; Guo, Xiao-jing; Gu, Lian

    2013-01-01

    Diabetes mellitus (DM) is one of the primary causes of premature death and disability worldwide. We performed a systematic review and meta-analysis of the published literature regarding the trends in prevalence, awareness, treatment, and control of diabetes mellitus in mainland China. PUBMED, EMBASE, Chinese Biomedical Database, China National Infrastructure database, Chinese Wan Fang database, and Chongqing VIP database were searched. Fifty-six eligible studies were included. Increasing tren...

  3. Calibration of Linked Hydrodynamic and Water Quality Model for Santa Margarita Lagoon

    Science.gov (United States)

    2016-07-01

    was used to drive the transport and water quality kinetics for the simulation of 2007–2009. The sand berm, which controlled the opening/closure of...TECHNICAL REPORT 3015 July 2016 Calibration of Linked Hydrodynamic and Water Quality Model for Santa Margarita Lagoon Final Report Pei...Linked Hydrodynamic and Water Quality Model for Santa Margarita Lagoon Final Report Pei-Fang Wang Chuck Katz Ripan Barua SSC Pacific James

  4. DNA characterization and polymorphism of KISS1 gene in Egyptian ...

    African Journals Online (AJOL)

    Aghomotsegin

    2015-07-29

    Jul 29, 2015 ... effect on litter size performance and many studies were carried out to identify ... gene (Wang et al., 2011), kit ligand (KITLG) gene (An et al., 2012) and bone ..... An XP, Han P, HouJX, Zhao HB, Yan Y, Ma T, Fang F, MengFX, Song. YX, Wang JG ... Chu MX, Zhao XH, Zhang YJ, Jin M (2010). Polymorphisms ...

  5. The Oncogenic Role of RhoGAPs in Basal-Like Breast Cancer

    Science.gov (United States)

    2016-04-01

    mouse models . c) In vivo tumorigenesis and metastasis assays. Milestones: Identify whether ArhGAP11A and RacGAP1 can promote tumor growth and/or...proteins. RacGAP1 is a component of the centralspindlin complex during mitosis and cytokinesis, but its function during interphase is not well...switches: Rho GTPase regulation during animal cell mitosis . Cell Signal 2014;26:2998-3006. 30. Zhao WM, Fang G. MgcRacGAP controls the assembly of the

  6. Patterns of non-participation in breast cancer screening

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær

    2015-01-01

    Screening for brystkræft blev introduceret i Region Midtjylland i 2008-2009 for kvinder i alderen 50-69 år for at øge overlevelsen ved at fange sygdommen tidligt. En høj deltagelse i screeningen er afgørende, hvis dødeligheden for brystkræft fremover skal reduceres. I første screeningsrunde delto...

  7. Departures from Axisymmetric Balance Dynamics during Secondary Eyewall Formation

    Science.gov (United States)

    2014-10-01

    institution, theNaval Postgraduate School (NPS) inMonterey, California. The authors thank Christopher Rozoff and two anonymous reviewers for their...combining the twomethods in themain body of this work, has been considered following a suggestion by D. Nolan (2014, personal communica- tion). This...10.1175/2010MWR3161.1. Rozoff, C. M., D. S. Nolan , J. P. Kossin, F. Zhang, and J. Fang, 2012: The roles of an expandingwind field and inertial stability

  8. 2011 AFMS Medical Research Symposium Held in National Harbor, Maryland on August 2-4, 2011. Volume 2: Enroute Care and Expeditionary Medicine Track

    Science.gov (United States)

    2011-08-01

    training in cardiopulmonary physiology and ECLS equipment and techniques. Military and civilian teams experienced in neonatal, pediatric , and adult...Gunst KevlnChi.IOtJ Dave Allen Alan Murdock ChrisWhito l)ave l orlleS PorlusloniRT Stepham• Sa’l>lge Nephrology Rex lnceldon Ray Fang Casey Cctonl...be measured using a noninvasive near- infrared spectroscopy probe to determine whether ORBC causes a decrease in StO2 compared to YRBC and FRBC

  9. Chinese Herbs Containing Aristolochic Acid Associated with Renal Failure and Urothelial Carcinoma: A Review from Epidemiologic Observations to Causal Inference

    OpenAIRE

    Yang, Hsiao-Yu; Chen, Pau-Chung; Wang, Jung-Der

    2014-01-01

    Herbal remedies containing aristolochic acid (AA) have been designated to be a strong carcinogen. This review summarizes major epidemiologic evidence to argue for the causal association between AA exposure and urothelial carcinoma as well as nephropathy. The exposure scenarios include the following: Belgian women taking slimming pills containing single material Guang Fang Ji, consumptions of mixtures of Chinese herbal products in the general population and patients with chronic renal failure ...

  10. Development of liposomal pemetrexed for enhanced therapy against multidrug resistance mediated by ABCC5 in breast cancer

    OpenAIRE

    Bai,Fang; Yin,You; Chen,Ting; Chen,Jihui; Ge,Meixin; Lu,Yunshu; Xie,Fangyuan; Zhang,Jian; Wu,Kejin; Liu,Yan

    2018-01-01

    Fang Bai,1–3,* You Yin,4,* Ting Chen,1,* Jihui Chen,1 Meixin Ge,2 Yunshu Lu,2 Fangyuan Xie,5 Jian Zhang,1 Kejin Wu,3 Yan Liu1,6 1Department of Pharmacy, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 2Department of General Surgery, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, 3Department of Breast Surgery, Obstetrics and Gynaecology Hospital, Fudan University, Shanghai, 4Department of Neurology, Changzheng...

  11. Expression of the gene cluster associated with the Escherichia coli pilus adhesin K99.

    Science.gov (United States)

    Lee, J H; Isaacson, R E

    1995-10-01

    The biogenesis of the pilus adhesin K99 is dependent on the expression of eight contiguous genes, fanA to fanH. Transposon mutants were prepared by using TnlacZ and TnphoA, and selected transposon mutants were used to measure expression of each K99 gene. Expression of the K99 genes is likely controlled at the transcription level, since in general, there were no differences between the results obtained with the two transposons. fanC was the most highly expressed, and fanD was expressed at very low levels. The expression of TnlacZ fusions in fanA and fanB fusions was high. Deletion of fanA, fanB, and part of fanC abolished the expression of fanD but had no effect on the distal genes fanE to fanH. To locate the DNA regions required for expression of fanE to fanH, deletion mutations were prepared and the effects on expression of fanE to fanH were determined. The deletion of a segment between fanD and fanE abolished fanE and fanF expression but did not affect fanG and fanH. The deletion of a portion of fanF (approximately 1 kb proximal to fanG) abolished the expression of fanG and fanH. These results indicate the presence of regulatory elements proximal to fanE and to fanG. Putative promoters were identified in these regions by DNA homology and by primer extension. A stem-loop structure that may act as a transcriptional attenuator of fanF was also found at the beginning of fanF. These data confirm our previous model of K99 transcriptional organization.

  12. Occurrence of cavernicolous ground beetles in Anhui Province, eastern China (Coleoptera, Carabidae, Trechinae).

    Science.gov (United States)

    Fang, Jie; Li, Wenbo; Tian, Mingyi

    2016-01-01

    Two new species of anophthalmic ground beetles belonging to the subfamily Trechinae are described: Cimmeritodes (Zhecimmerites) parvus Tian & Li, sp. n. and Wanoblemus wui Tian & Fang, gen. n., sp. n. Both were discovered in the limestone caves of Anhui Province in eastern China. Cimmeritodes (Zhecimmerites) parvus was found in caves Ziwei Dong, Xianren Dong and Qingtai Dong, whereas Wanoblemus wui was discovered in cave Baiyun Dong. This is the first record of cavernicolous ground beetles in Anhui Province, eastern China.

  13. Occurrence of cavernicolous ground beetles in Anhui Province, eastern China (Coleoptera, Carabidae, Trechinae

    Directory of Open Access Journals (Sweden)

    Jie Fang

    2016-10-01

    Full Text Available Two new species of anophthalmic ground beetles belonging to the subfamily Trechinae are described: Cimmeritodes (Zhecimmerites parvus Tian & Li, sp. n. and Wanoblemus wui Tian & Fang, gen. n., sp. n. Both were discovered in the limestone caves of Anhui Province in eastern China. C. (Z. parvus was found in caves Ziwei Dong, Xianren Dong and Qingtai Dong, whereas W. wui was discovered in cave Baiyun Dong. This is the first record of cavernicolous ground beetles in Anhui Province, eastern China.

  14. Medical Entomology Studies - XIII. The Myzomyia Series of Anopheles (Cellia) in Thailand, with Emphasis on Intra-Interspecific Variations (Diptera: Culicidae) (Contributions of the American Entomological Institute. Volume 17, Number 4, 1980)

    Science.gov (United States)

    1980-01-01

    pinpoint the collection site as Fang District, Chiang Mai Province in June 1952. However, no specimens confirming the record have been found in the...members of the Myzomyia Series in Thailand were in Barnes (1923a, b), who recorded aconitus from Bangkok and Chiang Mai , culicifacies from Chiang Mai , fluviatilis...as funestus Giles, = listoni Liston) from Bangkok and Chiang Mai and minimus from Bangkok. Barnes (1923b) also contained a key to the

  15. Beyond Lawrence: Ethnographic Intelligence for USSOCOM

    Science.gov (United States)

    2009-12-01

    consulate in Chiang Mai and almost 100 Peace Corps Volunteers throughout the country. The features Mali and Thailand have in common include some of the...Mopti, Timbuktu, and Sikasso; Thai citizens worry about the spread of Wahhabi mosques among the disenfranchised hill tribes north of Chiang Mai (Lintner...in the larger northern Thai cities along their trade routes in Chiang Mai , Chiang Rai, and Fang. Until the 1970s, northern Muslims of Chinese and

  16. High Power Broadband Multispectral Source on a Hybrid Silicon Chip

    Science.gov (United States)

    2017-03-14

    optical bandwidth of the erbium-doped- fiber -amplifier with densely-spaced frequency channels. To extend the spectral capacity of the Si-on-insulator...associated with non-uniform undercut at the taper tip across the chip after wet etching the active region. Figure 14. Normalized optical emission...Hutchinson, J., Shin, J.-H., Fish, G., and Fang, A., “Integrated silicon photonic laser sources for telecom and datacom,” in [National Fiber Optic

  17. Kuni 20. VIII on Tallinnas vastavatud kultuuritehases Polymer ennast sisse seadnud...Rael Artel Gallery

    Index Scriptorium Estoniae

    2004-01-01

    Näha saab G-Labi (Arturas Bumsteinas, Laura Garbstiene, Leedu) heliinstallatsiooni "Mirrors and Copulations", Kiwa heliteost "Hlör U Fang Axaxaxas mlö", Anu Allase kureeritud väljapanekut "Juhitud reisid/Guided Tours" (osalevad Liisi Peets, Katrin Tees, Piret Räni, Anu Vahtra, Daisy Lappard, rühmitus Tiit Sokk: Ulvi Tiit & Marili Sokk, Raivo Hool, Rataplan), Grace Schwindti (London) videot "Desire"

  18. Laser Journal (Selected Articles),

    Science.gov (United States)

    1982-09-10

    laser is described. The apparatus structure and some experimental results are reported. MATERIAL AND ELEMENT MAGNETO -OPTIC PROPERTIES OF Pr dYb),(1oAI...with a magneto -optical modulator. The measuring system is simple and sensitive, with reading accuracy of ±0.0050 and error 45%. STUDY ON EXPERIMENTAL...laser radiation therapy . He Fang de East Chiia Hospital APPLICATION OF N4d,:Y q LASER TO TREAT INTERNAL HEMERRHOID Zhuo Ruilin Zu Songlin (Shanghai

  19. SAR Imaging through the Earth’s Ionosphere

    Science.gov (United States)

    2013-11-06

    Xiaoqing Pi, Anthony Freeman, Bruce Chapman, Paul Rosen, and Zhenhong Li . Imaging ionospheric inhomogeneities using spaceborne synthetic aperture radar. J...resolution SAR phase correction. IEEE Trans. Aerosp. Electron. Syst., 30(3):827–835, 1994. [30] Lianlin Li and Fang Li . Ionosphere tomography based on...Manduchi and G. A. Mian . Accuracy analysis for correlation-based image registartion algorithms. In Proceedings of the 1993 IEEE International

  20. Resilience among caregivers of children with chronic conditions: a concept analysis

    OpenAIRE

    Lin, Fang-Yi; Rong,Jiin-Ru; Lee,

    2013-01-01

    Fang-Yi Lin, Jiin-Ru Rong, Tzu-Ying Lee Department of Nursing, School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, Republic of China Abstract: The purpose of this concept analysis is to uncover the essential elements involved in caregivers' resilience in the context of caring for children with chronic conditions. Walker and Avant's methodology guided the analysis. The study includes a literature review of conceptual definitions of car...

  1. Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom.

    Science.gov (United States)

    Peichoto, María E; Paes Leme, Adriana F; Pauletti, Bianca A; Batista, Isabel Correia; Mackessy, Stephen P; Acosta, Ofelia; Santoro, Marcelo L

    2010-09-01

    Patagonfibrase is a 57.5-kDa hemorrhagic metalloproteinase isolated from the venom of Philodryas patagoniensis (Patagonia Green Racer), a South American rear-fanged snake. Herein we demonstrate that patagonfibrase undergoes autolysis at its pH optimum (7.5) and at 37 degrees C, primarily producing a approximately 32.6 kDa fragment composed of disintegrin-like and cysteine-rich domains, as identified by mass spectrometry and N-terminal sequencing. The autolysis site for production of this fragment is similar to that observed for metalloproteinases from front-fanged Viperidae snake venoms. In the presence of Ca(2+), patagonfibrase was only partially autolysed, giving rise mainly to one fragment of approximately 52.2 kDa. In addition, calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms. Copyright © 2010 Elsevier B.V. All rights reserved.

  2. Chinese herbal dose in ancient and modern times: a comparative study.

    Science.gov (United States)

    He, Shimin

    2013-04-01

    Appropriate dose guarantees Chinese herb's safety and effectiveness. There are adult dose criteria for Chinese herbs in decoction in the Pharmacopoeia of the People's Republic of China (2010 Edition) at present. But Chinese herbs have been frequently used in much higher doses than the dose criteria. This study has been conducted to test the dependability of the dose criteria. Twenty Chinese herbs were selected as representatives and their adult doses in decoction in Bei Ji Qian Jin Yao Fang, a famous ancient literature, have been reviewed and compared with those in the Pharmacopoeia of the People's Republic of China (2010 Edition). The adult dose criteria for all these 20 Chinese herbs in the Pharmacopoeia of the People's Republic of China (2010 Edition) haven't covered those in Bei Ji Qian Jin Yao Fang. Furthermore, maximal adult doses in the dose criteria are much lower than those in Bei Ji Qian Jin Yao Fang. The dose criteria in the Pharmacopoeia of the People's Republic of China (2010 Edition) are not comprehensive enough. Studying ancient literatures is an effective method to gain precious Chinese herbs' dose data and helps for new dose criteria's establishment in the future.

  3. Density, viscosity and excess molar volume of binary mixtures of tri-n-octylamine + diluents (n-heptane, n-octane, n-nonane, and n-decane) at various temperatures

    International Nuclear Information System (INIS)

    Fang, Sheng; Zuo, Xiao-Bo; Xu, Xue-Jiao; Ren, Da-Hai

    2014-01-01

    Highlights: • Densities and viscosities of tri-n-octylamine + n-heptane, +n-octane, +n-nonane, or +n-decane are determined. • The excess molar volume is calculated. • The Grunberg and Nissan equation and Fang and He equation are used to correlate the binary viscosities. -- Abstract: Densities (ρ) and viscosities (η) for binary mixtures of tri-n-octylamine (TOA) + n-heptane, TOA + n-octane, TOA + n-nonane, and TOA + n-decane are determined at T (283.15, 293.15, and 303.15) K and atmospheric pressure. The excess molar volume is calculated from the density data and is correlated by a Redlich–Kister type equation. The excess molar volume is negative for all the four systems. The results show that the volume accommodation effect is predominant in these systems. The Grunberg and Nissan equation and Fang and He equation for binary mixtures are used to correlate the experimental viscosity data. The Fang and He equation gives an average absolute deviation (AAD%) of 0.8% for TOA with alkane mixtures, better than that of 3.8% given by the Grunberg and Nissan equation

  4. Clinical report of eight chief victims in 60Co radiation accident in Xinzhou

    International Nuclear Information System (INIS)

    Lou Bincheng; Ding Xiulan; Zhang Yaochen; Wu Hongjing; Guo Yang; Liu Qiujie; Han Wei; Huang Daikun; Miao Rongsheng; Fu Dong

    1998-01-01

    Objective: The author presents the clinical diagnosis and treatment of one patient (Fang) with acute radiation sickness (ARS) without obvious history of radiation exposure, the therapeutic effect of simple isolation and administration of GM-CSF and the condition of other seven patients in this group. Methods: After collecting detailed history and chromosome aberration analysis of lymphocytes, a definite diagnosis of ARS was made and infectious diseases and poisoning were ruled out. Results: When Fang was recovered using GM-CSF and simple isolation, 143 rings plus dicentric aberrations were found in 300 lymphocytes at intermitotic phase, 0.4368 'R + Dic' aver agedly exist in every cell, the whole body dose was estimated to be 2.3 Gy. Thus, acute radiation sickness of moderate degree was ascertained. It was deduced that 3 other members in Fang's family died of ARS. Altogether about 100 victims were found. Conclusion: When a patient suffers suspicious burn (erythema, blistering) but without a history of contact of heat or fire and caustic chemicals and the patient has nausea, vomiting, epilation and decrease in white blood cells, the possibility of radiation exposure exists. If some patients with above manifestations are found in a same family, the radiation exposure may be more probable. A simple isolation ward can be set in an ordinary hospital and GM-CSF should be used to reduce the course

  5. Reply to Comment by Roques et al. on "Base Flow Recession from Unsaturated-Saturated Porous Media considering Lateral Unsaturated Discharge and Aquifer Compressibility"

    Science.gov (United States)

    Liang, Xiuyu; Zhan, Hongbin; Zhang, You-Kuan; Schilling, Keith

    2018-04-01

    Roques et al. (https://doi.org/10.1002/2017WR022085) claims that they have proposed an exponential time step (ETS) method to improve the computing method of Liang et al. (https://doi.org/10.1002/2017WR020938) which used a constant time step (CTS) method on the derivative for dQ/dt in field data, where Q is the base flow discharge and t is the time since the start of base flow recession. This reply emphasizes that the main objective of Liang et al. (https://doi.org/10.1002/2017WR020938) was to develop an analytical model to investigate the effects of the unsaturated flow on base flow recession, not on the data interpretation methods. The analytical model indicates that the base flow recession hydrograph behaves as dQ/dt ˜aQb with the exponent b close to 1 at late times, which is consistent with previous theoretical models. The model of Liang et al. (https://doi.org/10.1002/2017WR020938) was applied to field data where the derivative of dQ/dt was computed using the CTS method, a method that has been widely adopted in previous studies. The ETS method proposed by Roques et al. (https://doi.org/10.1016/j.advwatres.2017.07.013) appears to be a good alternative but its accuracy needs further validation. Using slopes to fit field data as proposed by Roques et al. (https://doi.org/10.1002/2017WR022085) appears to match data satisfactorily at early times whereas it performs less satisfactorily at late times and leads to the exponent b being obviously larger than 1.

  6. Revisiting syntactic development in deaf and hearing children from a dependency approach. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

    Science.gov (United States)

    Yan, Jingqi

    2017-07-01

    Linguists are always endeavoring to discover universal rules to explain the language phenomena and interrelations [1]. Through a handful of corpus-based studies and a vast body of supporting evidence from psychological experiments, Liu, Xu and Liang [2] arrive at a conclusion on a general tendency toward dependency distance minimization (DDM) and relate this linguistic universal to the constraints of memory. Dependency distance (DD) is hereby introduced as a linguistic property, with quantitative features of frequency, and profound cognitive grounding as well. However, since the authors do not include language development, in this comment, I would like to discuss some future prospects from this perspective.

  7. Modelling of coil-loaded wire antenna using composite multiple domain basis functions

    CSIR Research Space (South Africa)

    Lysko, AA

    2010-03-01

    Full Text Available - tional Electromagnetics, Artech House, 2001. 3. Rogers, S. D. and C. M. Butler, \\An e–cient curved-wire integral equation solution technique," IEEE Trans. Ant. and Propag., 70{79, Vol. 49, Jan. 2001. 4. Mosig, J. and E. Suter, \\A multilevel divide.... 8. Wan, J. X., J. Lei, and C.-H. Liang, \\An e–cient analysis of large-scale periodic microstrip antenna arrays using the characteristic basis function method," Progress In Electromagnetics Research, PIER 50, 61{81, 2005. 9. Taguchi, M., K...

  8. Robust Inference with Multi-way Clustering

    OpenAIRE

    A. Colin Cameron; Jonah B. Gelbach; Douglas L. Miller; Doug Miller

    2009-01-01

    In this paper we propose a variance estimator for the OLS estimator as well as for nonlinear estimators such as logit, probit and GMM. This variance estimator enables cluster-robust inference when there is two-way or multi-way clustering that is non-nested. The variance estimator extends the standard cluster-robust variance estimator or sandwich estimator for one-way clustering (e.g. Liang and Zeger (1986), Arellano (1987)) and relies on similar relatively weak distributional assumptions. Our...

  9. Transformation of Taiwan’s Reserve Force

    Science.gov (United States)

    2017-01-01

    benefited tremen- dously from their deep knowledge across the range of issues associated with reserve force reforms generally, and reserve force...Penghu Wude Joint Counter Amphibious Exercise [澎湖五德聯信聯合反登陸操演],” 2013. 18 For details on Taiwan’s short-range air defense capabilities, see Kuo Wen ...opinion/national-service-for-the-21st-century Kuo Wen -liang, National Defense Education: Defense Science and Technology [全民國防教育國防科技], Taipei: NWCD

  10. Comment on “Time-changed geometric fractional Brownian motion and option pricing with transaction costs” by Hui Gu et al.

    Science.gov (United States)

    Guo, Zhidong; Song, Yukun; Zhang, Yunliang

    2013-05-01

    The purpose of this comment is to point out the inappropriate assumption of “3αH>1” and two problems in the proof of “Theorem 3.1” in section 3 of the paper “Time-changed geometric fractional Brownian motion and option pricing with transaction costs” by Hui Gu et al. [H. Gu, J.R. Liang, Y. X. Zhang, Time-changed geometric fractional Brownian motion and option pricing with transaction costs, Physica A 391 (2012) 3971-3977]. Then we show the two problems will be solved under our new assumption.

  11. Spectroscopic Signatures for Interlayer Coupling in MoS2-WSe2 van der Waals Stacking

    Science.gov (United States)

    2014-09-07

    K. Direct Imaging of Band Profile in Single Layer MoS2 on Graphite: Quasiparticle Energy Gap, Metallic Edge States, and Edge Band Bending. Nano Lett...1403.6455v1. 51. Shi, H.; Pan, H.; Zhang, Y.-W.; Yakobson, B. I. Quasiparticle Band Structures and Optical Properties of Strained Mono- layer MoS2 and WS2...Phys. Rev. B 2013, 87, 155304. 52. Liang, Y.; Huang, S.; Soklaski, R.; Yang, L. Quasiparticle Band-edge Energy and Band Offsets of Monolayer of

  12. Lower Confidence Bounds for the Probabilities of Correct Selection

    Directory of Open Access Journals (Sweden)

    Radhey S. Singh

    2011-01-01

    Full Text Available We extend the results of Gupta and Liang (1998, derived for location parameters, to obtain lower confidence bounds for the probability of correctly selecting the t best populations (PCSt simultaneously for all t=1,…,k−1 for the general scale parameter models, where k is the number of populations involved in the selection problem. The application of the results to the exponential and normal probability models is discussed. The implementation of the simultaneous lower confidence bounds for PCSt is illustrated through real-life datasets.

  13. A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo

    OpenAIRE

    Ge, Xiangting; Feng, Zhiguo; Xu, Tingting; Wu, Beibei; Chen, Hongjin; Xu, Fengli; Fu, Lili; Shan, Xiaoou; Dai, Yuanrong; Zhang, Yali; Liang, Guang

    2016-01-01

    Xiangting Ge,1,2,* Zhiguo Feng,1,* Tingting Xu,2 Beibei Wu,3 Hongjin Chen,1 Fengli Xu,3 Lili Fu,1 Xiaoou Shan,3 Yuanrong Dai,2 Yali Zhang,1 Guang Liang11Chemical Biology Research Center, School of Pharmaceutical Sciences, 2Department of Pulmonary Medicine, The 2nd Affiliated Hospital, 3Department of Pediatrics, The 2nd Affiliated Hospital, Wenzhou Medical University, Wenzhou, People’s Republic of China*These authors contributed equally to this workAbstract: Sepsis remains a leading ...

  14. A small skull from Flores dated to the 20th century

    DEFF Research Database (Denmark)

    Villa, Chiara; Persson, Liselott; Alexandersen, Verner

    2012-01-01

    A human skull with mandible from the Ngada District on the island of Flores, Indonesia, is described in order to contribute to the knowledge of variation in cranial architecture, which is important in interpretations of evolutionary cerebralisation. The skull was excavated in 1924 and sent...... to the National Museum in Copenhagen. The "Copenhagen Flores" (CF) male skull is radiocarbon-dated and of modern age. The cranium is small, but larger than e.g. Liang Bua skull (LB1) in every measurement. The (CT-scan based) cranial capacity of 1258 ml is normal for modern humans, but somewhat lower than values...

  15. The absent father of Sino-French cinema: Contemporary Taiwanese cinema and 1950s French auteurs

    OpenAIRE

    Bloom, ME

    2014-01-01

    © 2014 Taylor & Francis. In contemporary Sino-French cinema, father characters who are dead, long lost or geographically distant leave gaping holes in the lives of the offspring left behind. The absent fathers in Sino-French films by Taiwanese auteurs Cheng Yu-chieh, Hou Hsiao-hsien and Tsai Ming-liang serve as metaphors for French auteurs. French New Wave films constitute the majority of the intertexts; however, early 1950s French cinema and even late nineteenth-century painting reflect th...

  16. Selected translations and analysis of "Further biographies of nuns"

    OpenAIRE

    Tho, Annlaug

    2008-01-01

    ‘Further Biographies of Nuns’ was compiled by Master Zhenhua (1908 -1947) in the 1940s and presents the biographies of 200 Buddhist nuns from the Liang Dynasty (502-557) to the Republic of China (1912-1949). This thesis presents the translation of twelve biographies from ‘Further Biographies of Nuns.’ Though the Buddhist monks of China have been a source for many biographies and studies by both Asian and Western scholars throughout history, Chinese Buddhist nuns have received little atte...

  17. A Training Program in Breast Cancer Research Using NMR Techniques

    Science.gov (United States)

    2006-07-01

    of Mammographic Masses, IEEE Transactions on Medical Imaging, 2002, vol. 21, No. 2, (Accepted for publication). 9. Mendez AJ, Tahoces PG, Lado MJ...Medical Physics, 2001, Vol. 28, no. 2, pp. 250-258. [7] Mendez AJ, Tahoces PG, Lado MJ, Souto M., Vidal JJ, Computer-aided diagnosis: Automatic...resistant epidermal carcinoma cells Xing-Jie Liang,a Jun-Jie Yin,b Jien-Wei Zhou,c Paul C. Wang,c Barbara Taylor,a Carol Cardarelli,a Michael Kozar,d Raynard

  18. Water reclamation for aquifer recharge at the eight case study sites: a cross case analysis

    CSIR Research Space (South Africa)

    Le Corre, K

    2012-06-01

    Full Text Available , Tredoux, Gideon, Wintgens, Thomas, Cheng Xuzhou, Yu, Liang and Zhao, Xuan Abstract: Water scarcity combined with the quality deterioration of freshwater due to the rapid augmentation of population and industrial development is a major concern... stream_source_info Genthe_2012_ABSTRACT.pdf.txt stream_content_type text/plain stream_size 1118 Content-Encoding ISO-8859-1 stream_name Genthe_2012_ABSTRACT.pdf.txt Content-Type text/plain; charset=ISO-8859-1 Water...

  19. Single-mode Laser by Parity-time Symmetry Breaking

    Science.gov (United States)

    2014-11-21

    solenoid -like Pds5B that reside in direct proximity to Wapl and the Smc3-Scc1 in- teraction interface (fig. S13), implying that Wapl and Pds5 control the...accepted 26 September 2014 10.1126/science.1256904 REPORTS ◥ OPTICS Single-mode laser by parity-time symmetry breaking Liang Feng,1* Zi Jing Wong,1...Ren-Min Ma,1* Yuan Wang,1,2 Xiang Zhang1,2† Effective manipulation of cavity resonant modes is crucial for emission control in laser physics and

  20. Phytochemicals and bioactivities of Anemone raddeana Regel: a review.

    Science.gov (United States)

    Sun, Yong-Xu; Liu, Ji-Cheng; Liu, Da-You

    2011-11-01

    Anemone raddeana, usually called as'"Toujian Liang" in China, is an Anemone herb belonging to the Ranunculaceae family. Until now there are in total 67 of chemical components identified including triterpenoids, steroids, lactones, fats and oils, saccharide and alkaloids. A broad spectrum of pharmacological activity of A. raddeana compounds have been reported, such as antitumor, antimicrobial, anti-inflammatory, sedative and analgesic activites, as well as anti-convulsant and anti-histamine effects. In view of this, we initiated this short review to present the phytochemical and pharmacological profile of A. raddeana to support future studies in this discipline.

  1. Porous and Phase Change Nanomaterials For Photonic Applications

    Science.gov (United States)

    2014-08-28

    Y. Han , M. S. Zhao, G. Morthier, and R. Baets. Athermal silicon-on-insulator ring resonators by overlaying a polymer cladding on narrowed waveguides...integrated photonics. Advanced Materials, 22(23):2561, 2010. [152] T. Sondergaard, S. M. Novikov, T. Holmgaard, R. L. Eriksen, J. Beermann, Z. H. Han , K...726, 2011. [181] N. N. Feng, D. Z. Feng, S. R. Liao, X. Wang, P. Dong, H. Liang, C. C. Kung , W. Qian, J. Fong, R. Shafiiha, Y. Luo, J. Cunningham, A. V

  2. An Integrated Command and Control Architecture Concept for Unmanned Systems in the Year 2030

    Science.gov (United States)

    2010-06-01

    Tan Yean Wee ME5 Tong Kee Leong  Lu  Chin  Leong Chia Boon  Chye Henry Seet ME5 Lo Chee Hun ME5 Gabriel Tham Ho Liang Yoong Raymond Quah Quek Chee Luan Ang...Chia Tan Wei Chieh Chia Boon Chye Yionon Costica Lim Wei Han Eugene Ng Wei Gee Delvin...Gho Lo Chee Hun Tan Chin Wah John Ang Kha Luna Lu Chin Leong Tong Kee Leong

  3. [Effects of blueberry on apoptosis and expression of Bcl-2 and Bax in HSC-T6].

    Science.gov (United States)

    Lu, Shuang; Cheng, Mingliang; Yang, Demeng; Liu, Yang; Guan, Li; Wu, Jun

    2015-08-18

    To investigate the effects of blueberry on the apoptosis, expression of Bcl-2 and Bax in rat hepatic stellate cell (HSC-T6). 10% blueberry serum at low, middle and high dose, 10% Fu-Fang-Bie-Jia-Ruan-Gan tablet serum and 10% saline serum were prepared by method of serum pharmacology. Subcultured HSC-T6 was divided into saline serum control group, blueberry serum at low, middle, high dose and Fu-Fang-Bie-Jia-Ruan-Gan tablet serum group, and then was respectively incubated at different dose of 10% blueberry serum, 10% Fu-Fang-Bie-Jia-Ruan-Gan tablet serum and 10% saline serum for 72 hours.Apoptosis of HSC-T6 was detected using flow cytometry with annexin V FITC/PI double staining. The expression of Bcl-2 and Bax in HSC-T6 were examined using immunocytochemistry and Western blotting, respectively. There was no significant difference for HSC-T6 Bax protein expression in the low, middle and high dose blueberry serum groups, compared with saline serum control group, respectively.In the high-dose blueberry serum group HSC-T6 early and total apoptosis rate increased significantly compared with the saline serum control group (5.55% ± 0.98% vs 2.53% ± 0.46%, 7.01% ± 1.05% vs 2.96% ± 0.81%, both Pblueberry serum group showed no significant difference with the saline serum control group. Blueberry can induce HSC-T6 apoptosis by down-regulating Bcl-2 expression and decreasing the ratio of Bcl-2/Bax in HSC-T6 cells, so it may have potential interference effects on hepatic fibrosis.

  4. Recent development in clusters of rare earths and actinides. Chemistry and materials

    International Nuclear Information System (INIS)

    Zheng, Zhiping

    2017-01-01

    This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

  5. A Multiscale Modeling System: Developments, Applications, and Critical Issues

    Science.gov (United States)

    Tao, Wei-Kuo; Lau, William; Simpson, Joanne; Chern, Jiun-Dar; Atlas, Robert; Khairoutdinov, David Randall Marat; Li, Jui-Lin; Waliser, Duane E.; Jiang, Jonathan; Hou, Arthur; hide

    2009-01-01

    The foremost challenge in parameterizing convective clouds and cloud systems in large-scale models are the many coupled dynamical and physical processes that interact over a wide range of scales, from microphysical scales to the synoptic and planetary scales. This makes the comprehension and representation of convective clouds and cloud systems one of the most complex scientific problems in Earth science. During the past decade, the Global Energy and Water Cycle Experiment (GEWEX) Cloud System Study (GCSS) has pioneered the use of single-column models (SCMs) and cloud-resolving models (CRMs) for the evaluation of the cloud and radiation parameterizations in general circulation models (GCMs; e.g., GEWEX Cloud System Science Team 1993). These activities have uncovered many systematic biases in the radiation, cloud and convection parameterizations of GCMs and have led to the development of new schemes (e.g., Zhang 2002; Pincus et al, 2003; Zhang and Wu 2003; Wu et al. 2003; Liang and Wu 2005; Wu and Liang 2005, and others). Comparisons between SCMs and CRMs using the same large-scale forcing derived from field campaigns have demonstrated that CRMs are superior to SCMs in the prediction of temperature and moisture tendencies (e.g., Das et al. 1999; Randall et al 2003b; Xie et al. 2005).

  6. Recent development in clusters of rare earths and actinides. Chemistry and materials

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Zhiping (ed.) [Arizona Univ., Tucson, AZ (United States). Dept. of Chemistry and Biochemistry

    2017-02-01

    This book contains the following eight contributions: 1. Lanthanide Hydroxide Cluster Complexes via Ligand-Controlled Hydrolysis of the Lanthanide Ions (Zhonghao Zhang, Yanan Zhang, and Zhiping Zheng); 2. Synthesis and Structures of Lanthanide-Transition Metal Clusters (Xiu-Ying Zheng, Xiang-Jian Kong, and La-Sheng Long); 3. Hydrothermal Synthesis of Lanthanide and Lanthanide-Transition-Metal Cluster Organic Frameworks via Synergistic Coordination Strategy (Jian-Wen Cheng and Guo-Yu Yang); 4. Oxo Clusters of 5f Elements (Sarah Hickam and Peter C.); 5. Construction and Luminescence Properties of 4f and d-4f Clusters with Salen-Type Schiff Base Ligands (Xiaoping Yang, Shiqing Wang, Chengri Wang, Shaoming Huang, and Richard A.); 6. 4f-Clusters for Cryogenic Magnetic Cooling (Yan-Cong Chen, Jun-Liang Liu, and Ming-Liang Tong); 7. Lanthanide Clusters Toward Single-Molecule Magnets (Tian Han, You-Song Ding, and Yan-Zhen Zheng); 8. Molecular Rare Earth Hydride Clusters (Takanori Shima and Zhaomin Hou).

  7. Comparison of autogeneic and allogeneic natural killer cells immunotherapy on the clinical outcome of recurrent breast cancer

    Directory of Open Access Journals (Sweden)

    Liang S

    2017-08-01

    Full Text Available Shuzhen Liang,1,2 Kecheng Xu,1,2 Lizhi Niu,1,2 Xiaohua Wang,1 Yingqing Liang,1 Mingjie Zhang,3 Jibing Chen,1,2 Mao Lin1,2 1Department of Central Laboratory, Fuda Cancer Hospital, Jinan University School of Medicine, Guangzhou, Guangdong, China; 2Fuda Cancer Institute, Guangzhou, Guangdong, China; 3Hank Bioengineering Co., Ltd, Shenzhen, China Abstract: In the present study, we aimed to compare the clinical outcome of autogeneic and allogeneic natural killer (NK cells immunotherapy for the treatment of recurrent breast cancer. Between July 2016 and February 2017, 36 patients who met the enrollment criteria were randomly assigned to two groups: autogeneic NK cells immunotherapy group (group I, n=18 and allogeneic NK cells immunotherapy group (group II, n=18. The clinical efficacy, quality of life, immune function, circulating tumor cell (CTC level, and other related indicators were evaluated. We found that allogeneic NK cells immunotherapy has better clinical efficacy than autogeneic therapy. Moreover, allogeneic NK cells therapy improves the quality of life, reduces the number of CTCs, reduces carcinoembryonic antigen and cancer antigen 15-3 (CA15-3 expression, and significantly enhances immune function. To our knowledge, this is the first clinical trial to compare the clinical outcome of autogeneic and allogeneic NK cells immunotherapy for recurrent breast cancer. Keywords: clinical outcome, autogeneic, allogeneic, natural killer cells, recurrent breast cancer

  8. An Efficient Quantum Somewhat Homomorphic Symmetric Searchable Encryption

    Science.gov (United States)

    Sun, Xiaoqiang; Wang, Ting; Sun, Zhiwei; Wang, Ping; Yu, Jianping; Xie, Weixin

    2017-04-01

    In 2009, Gentry first introduced an ideal lattices fully homomorphic encryption (FHE) scheme. Later, based on the approximate greatest common divisor problem, learning with errors problem or learning with errors over rings problem, FHE has developed rapidly, along with the low efficiency and computational security. Combined with quantum mechanics, Liang proposed a symmetric quantum somewhat homomorphic encryption (QSHE) scheme based on quantum one-time pad, which is unconditional security. And it was converted to a quantum fully homomorphic encryption scheme, whose evaluation algorithm is based on the secret key. Compared with Liang's QSHE scheme, we propose a more efficient QSHE scheme for classical input states with perfect security, which is used to encrypt the classical message, and the secret key is not required in the evaluation algorithm. Furthermore, an efficient symmetric searchable encryption (SSE) scheme is constructed based on our QSHE scheme. SSE is important in the cloud storage, which allows users to offload search queries to the untrusted cloud. Then the cloud is responsible for returning encrypted files that match search queries (also encrypted), which protects users' privacy.

  9. Thermally induced nano-structural and optical changes of nc-Si:H deposited by hot-wire CVD

    CSIR Research Space (South Africa)

    Arendse, CJ

    2009-04-01

    Full Text Available 55 56 57 58 59 60 61 62 63 64 65 15 [26] D. Stryahilev, F. Diehl, B. Schroeder, J. Non-Cryst. Solids 266–269, 166 (2000) [27] M. H. Brodsky, M. Cardona, and J. J. Cuomo, Phys. Rev. B 16. 3556 (1977) [28] H. Shanks, C. J. Fang, L. Ley... stream_source_info Arendse_d1_2009.pdf.txt stream_content_type text/plain stream_size 28527 Content-Encoding UTF-8 stream_name Arendse_d1_2009.pdf.txt Content-Type text/plain; charset=UTF-8...

  10. Thermal stability of the optical band gap and structural order in hot-wire-deposited amorphous silicon

    CSIR Research Space (South Africa)

    Arendse, CJ

    2009-01-01

    Full Text Available . Cardona, J. J. Cuomo, Phys. Rev. B 16 (1977) 3556 14. H. Shanks, C.J. Fang, L. Ley, M. Cardona, F.J. Desmond, S. Kalbitzer, Phys. Status Solidi B 100 (1980) 43 15. A.M. Brockhoff, Ph.D. thesis, Utrecht University, Utrecht, The Netherlands, 2001 16. D... stream_source_info Arendse_d2_2009.pdf.txt stream_content_type text/plain stream_size 12859 Content-Encoding UTF-8 stream_name Arendse_d2_2009.pdf.txt Content-Type text/plain; charset=UTF-8 1 Thermal stability...

  11. Pilot Comparative Case Study on Eco-innovation Dynamics at firm level

    DEFF Research Database (Denmark)

    Yang, Yan; Du, Xiangyun; SHAO, Yunfei

    2010-01-01

    This paper pays special attention to eco-innovations dynamics at firm level. Triple helix twins are employed to disclose the complex collaborations within and across the case companies, as it provides us the possibilities of looking beyond the simpler, linear model of innovation and. Grundfos...... and environmental regulations. Dong Fang (China) is identified as a company at the very beginning of eco-innovation, as its compliance with environmental standards such as ISO 9001, ISO14001, OHSAS 18001 is absent at present; its collaborations with government and universities or research institutions...... helix twins and eco-innovation dynamics is addressed....

  12. Effect of Laser Power on Material Efficiency, Layer Height and Width of Laser Metal Deposited Ti6Al4V

    CSIR Research Space (South Africa)

    Mahamood, RM

    2012-10-01

    Full Text Available /sec) during deposition is   600  DFRP TPm ----------------------------------- (3) PFR is the powder flow rate in g/min and the 60 in equation 3 is a conversion factor for the powder flow rate to g/sec. The powder efficiency (μ) is given by:   100/ 0... Alloys for Aerospace Applications, in: Titanium and Titanium Alloys, Advanced Engineering Materials, 5, 2003, pp.419-427. [3] Y. Lu, H.B. Tang, Y.L. Fang, D. Liu, H.M. Wang, Microstructure evolution of sub-critical annealed laser deposited Ti–6Al–4V...

  13. Enhanced methanol oxidation and oxygen reduction reactions on palladium-decorated FeCo@Fe/C core–shell nanocatalysts in alkaline medium

    CSIR Research Space (South Africa)

    Fashedemi, OO

    2013-12-01

    Full Text Available . Zhong, J. Luo, B. Fang, B. N. Wanjala, P. N. Njoki, R. Loukrakpam and J. Yin, Nanotechnology, 2010, 21, 062001. 39 C. L. Lee, H. P. Chiou, C. M. Syu, C. R. Liu, C. C. Yang and C. C. Syu, Int. J. Hydrogen Energy, 2011, 36, 12706–12714. 40 K. J. Mayrhofer..., 12, 1102–1106. 2 Y. W. Lee, M. Kim, Y. Kim, S. W. Kang, J. H. Lee and S. W. Han, J. Phys. Chem. C, 2010, 114, 7689–7693. 3 C. Zhu, S. Guo and S. Dong, J. Mater. Chem., 2012, 22, 14851–14855. 4 C. Jeyabharathi, P. Venkateshkhumar, J. Mathiyarasau and K...

  14. Exploring the experiences of older Chinese adults with comorbidities including diabetes: surmounting these challenges in order to live a normal life

    OpenAIRE

    Ho, Hsiu-Yu; Chen, Mei-Hui; Lou, Meei-Fang

    2018-01-01

    Hsiu-Yu Ho,1,2 Mei-Hui Chen,2,3 Meei-Fang Lou1 1School of Nursing, College of Medicine, National Taiwan University, 2Department of Nursing, Yuanpei University of Medical Technology, 3National Taipei University of Nursing and Health Sciences, Taipei, Taiwan, Republic of China Background: Many people with diabetes have comorbidities, even multimorbidities, which have a far-reaching impact on the older adults, their family, and society. However, little is known of the experience of older adult...

  15. [Buddhist influences on Sun Simiao's precious prescriptions for emergency].

    Science.gov (United States)

    Zhu, J

    1999-10-01

    Living in a period when the Buddhism was quite flourishing, Sun had a close contact with the monk Dao Xuan, the founder of Nanshan Sect Buddhism. Sun's Quian jin fang adopted all schools including Buddhism, evidenced by the following 3 aspects: 1) Direct Buddhist influence, mainly on medical morality; 2) Indian medicine coming together with Buddhism, including the theory of "four - element theory", the conception of all matters are medicines, pills of all disorders, recipes, and keep - fit art. Buddhism acts as a carrier here; 3) the achievements of treatment for beriberi by monks. However, Buddhist influence was far inferior to Taoism as far as Sun's work is concerned.

  16. Xiyang chaogong dianlu

    OpenAIRE

    Sonnendecker, Klaus Michael

    2010-01-01

    This text contains an annotated translation into German of Huang Xingzeng's Xiyang chaogong dianlu (Records of Audiences and Tributes from the Western Ocean), which was compiled in A.D. 1520; the edition used, was prepared and annoted by Xie Fang and published in Beijing, in 1982. It consists of three juan (books), in which the author treats twenty-three countries, that had a tributary status to the Ming empire, when Zheng He made his seven voyages to the Indian Ocean. The a...

  17. Leguay Jean-Pierre, 1999, La pollution au Moyen-Âge, Edition Jean-Paul Gisserot, Paris

    Directory of Open Access Journals (Sweden)

    Sandrine Rousseau

    2004-10-01

    Full Text Available Si vous aviez du Moyen-Âge la vision qu’en donnent certaines gravures : une belle princesse au bras d’un preux chevalier, Jean-Pierre Leguay, professeur d’histoire médiévale à l’université de Haute-Normandie, risque de vous surprendre. En effet, son ouvrage, La pollution au Moyen-Âge modifiera sans doute cette vision idyllique. Pour commencer, sachez que la princesse et son preux chevalier ont les pieds dans la boue, une boue composée de la fange, d’excréments humains, de déchets des bouchers...

  18. Therapeutic Targeting of Spliceosomal-Mutant Acquired Bone Marrow Failure Disorders

    Science.gov (United States)

    2017-05-01

    spliceosomal mutant cells . This effort has also highlighted a requirement for innate immune signaling in SF3B1-mutant MDS and has implicated a few specific...relative to single-mutant cells (Figure 5A). As innate immune signaling has been implicated in MDS pathogenesis (Basiorka et al., 2016; Fang et al...Sato et al., 2005; Tang et al., 2008; Vink et al., 2013; Xin et al., 2017). Here, we observed that SF3B1K700E/+ human lymphoid leukemia cells (NALM-6

  19. Sources of organic matter and microbial community structure in the sediments of the Visakhapatnam Harbour, east coat of India

    Digital Repository Service at National Institute of Oceanography (India)

    Harji, R.R; Bhosle, N.B.; Garg, A.; Sawant, S.S.; Venkat, K.

    Trench at 11,000 m. Deep Sea Research Part I: Oceanographic Research Papers 47, 1173- 1182. Fang, J., Kato, C., Sato, T., Chan, O., McKay, D., 2004. Biosynthesis and dietary uptake of polyunsaturated fatty acids by peizophilic bacteria. Comparative... lipids and community structure in estuaries. Aquatic Microbial Ecology 42, 105-117. Hedges, J.I., Keil, R.G., 1995. Sedimentary organic matter preservation: an assessment and speculative synthesis. Marine Chemistry 49, 81-115. Hedges, J.I., Keil, R...

  20. Thin film Ag superlens towards lab-on-a-chip integration

    DEFF Research Database (Denmark)

    Jeppesen, Claus; Nielsen, Rasmus Bundgaard; Boltasseva, Alexandra

    2009-01-01

    A thin metal film near-field superlens, as originally suggested by Pendry and realized by Fang et al. and Melville et al., is investigated with emphasis on materials suitable for integration on a lab-on-a-chip platform. A chemically resistant cyclo-olefin copolymer (COC), mr-I-T85 from microresist...... technology, is applied as dielectric matrix/spacer for an Ag thin film superlens. The superlens successfully resolves 80 nm half-pitch gratings when illuminated with UV radiation at a free space wavelength of 365 nm. The superlens design, fabrication and characterization is discussed....

  1. Fatigue-Arrestor Bolts

    Science.gov (United States)

    Onstott, Joseph W.; Gilster, Mark; Rodriguez, Sergio; Larson, John E.; Wickham, Mark D.; Schoonover, Kevin E.

    1995-01-01

    Bolts that arrest (or, more precisely, retard) onset of fatigue cracking caused by inelastic strains developed. Specifically developed to be installed in flange holes of unrestrained rocket engine nozzle. Fanges sometimes used to bolt nozzle to test stand; however, when rocket engine operated without this restraint, region around bolt holes experience severe inelastic strains causing fatigue cracking. Interference fits introduce compressive preloads that retard fatigue by reducing ranges of strains. Principle of these fatigue-arrestor bolts also applicable to holes in plates made of other materials and/or used for different purposes.

  2. The status of taxonomy and venom in sea snakes

    DEFF Research Database (Denmark)

    Redsted Rasmussen, Arne; Sanders, Kate L.

    2017-01-01

    of the poison-fangs on the maxillary bone (proteroglyphous). Globally there are some 70 species of sea snake found in the tropical and subtropical waters of the Indian Ocean and the Pacific Ocean. Most species are found in the Indo-Malayan Archipelago, the China Sea, Indonesia, and the Australian region...... ‘Hydrophis’ lineage contains about 50 species, many of which have very wide distributions across the Indo-Pacific. The Aipysurus group has experienced a relatively stable taxonomic history, and mitochondrial phylogenies of sampled taxa are well resolved. In contrast, Hydrophis group species have until...

  3. TABLE OF CINTENTS and ABSTRACTS reprinted from ACTA PHYSICA SINICA,Vol.50,No.6(2001)(in Chinese)

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@0000 GENERAL 0330 Conservation Laws of Relativistic Variable Mass Systems…………………………… Fang Jian-hui (1005) 0340 Simulation of Shock Waves Using a Lattice Boltz mann Equation Model …………………… Feng Shi-de, Michihisa Tsutahara (1010) 0365 Double-Wave Function of RLC Circuit After Quantization…………………… Long Chao-yun, Liu Bo (1014) 0420 The Nernst Theorem and Statistical Entropy of the Scalar field in Reissner-Nordstrom Geometry……………………Zhao Ren, Zhang Li-chun (1018)

  4. Elliptic partial differential equations

    CERN Document Server

    Han, Qing

    2011-01-01

    Elliptic Partial Differential Equations by Qing Han and FangHua Lin is one of the best textbooks I know. It is the perfect introduction to PDE. In 150 pages or so it covers an amazing amount of wonderful and extraordinary useful material. I have used it as a textbook at both graduate and undergraduate levels which is possible since it only requires very little background material yet it covers an enormous amount of material. In my opinion it is a must read for all interested in analysis and geometry, and for all of my own PhD students it is indeed just that. I cannot say enough good things abo

  5. Distribution and sources of aliphatic hydrocarbons and fatty acids in surface sediments of a tropical estuary south west coast of India (Cochin estuary)

    Digital Repository Service at National Institute of Oceanography (India)

    Gireeshkumar, T.R.; Deepulal, P.M.; Chandramohanakumar, N.

    acid biomarkers and stable isotopes. Estuarine, Coastal and Shelf Science, 70, 271–286. Andrews, J. E., Greenaway, A. M., & Dennis, P. F. (1998). Combined carbon isotope and C/N ratios as indictors of source and fate of organic matter in a poorly.... (1997). Even n- alkane predominances on the Amazon Shelf and a Northeast Pacific Hydrothermal System. Naturwissenschaften, 84, 415–420. Fang, J., Kato, C., Sato, T., Chan, O., & McKay, D. (2004). Biosynthesis and dietary uptake of polyunsaturated fatty...

  6. Materials Research Society Symposium Proceedings Held in Boston, Massachusetts on 4-6 December 1991. Low Temperature (LT) GaAs and Related Materials. Volume 241.

    Science.gov (United States)

    1992-09-14

    Phys. Rev. Letts., 58, 1987, p2 567. 4. Ypong-Eon Him, N.Otsuka. J.Kleni and Il~lorkoc .ppl. Phy3s. L.ett., 51. 1987, p20 13. .5. Akiko Gomiyo...559-563, June 1978. , - I I I II III ~ ll I I I IIIIfa 198 131 R. Yamamoto , A. Higashisaka, and F. Hasegawa. "Light Emission and Burnout...Appl. Phys. Left. 58, 65 (1991), and references therein. 4. H. Yamamoto , Z. Fang, and D. Look, Appl. Phys. Lett. 5Z, 1537 (1990), and references

  7. Targeting Histone Abnormality in Triple Negative Breast Cancer

    Science.gov (United States)

    2016-08-01

    M.D., Ph.D. 3 1. Huang Y, Johnson KR, Norris JS, Fan W. NF-κB/IκB signaling pathway may contribute to the mediation of paclitaxel-induced...of paclitaxel-induced apoptosis in human tumor cell lines. Mol. Pharmacol., 61: 105-113, 2002. PMID: 11752211 3. Huang Y, Fang Y, Dziadyk JM, Norris ...has been shown to have important roles in many diseases including cancer.17,18 In this study, we addressed the following clinically relevant issues

  8. Harm avoidance and depression, anxiety, insomnia, and migraine in fifth-year medical students in Taiwan

    OpenAIRE

    Chen CY; Yu NW; Huang TH; Wang WS; Fang JT

    2018-01-01

    Ching-Yen Chen,1–3 Nan-Wen Yu,2–4 Tien-Hao Huang,4 Wei-Shin Wang,4 Ji-Tseng Fang2,3,5 1Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan; 2School of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Medical Education Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan; 5Department of Nephrology, Chang Gung Memorial Hospital, Linkou, Taiwan Purpose: During medical school tra...

  9. Harm avoidance and depression, anxiety, insomnia, and migraine in fifth-year medical students in Taiwan

    OpenAIRE

    Chen,Ching-Yen; Yu,Nan-Wen; Huang,Tien-Hao; Wang,Wei-Shin; Fang,Ji-Tseng

    2018-01-01

    Ching-Yen Chen,1–3 Nan-Wen Yu,2–4 Tien-Hao Huang,4 Wei-Shin Wang,4 Ji-Tseng Fang2,3,5 1Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan; 2School of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Medical Education Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan; 5Department of Nephrology, Chang Gung Memorial Hospital, Linkou, Taiwan Purpose: During medical sc...

  10. Måleegenskaper ved den norske versjonen av ADHD Rating Scale IV, Skoleversjon (ADHD-RS-IV Skole)

    OpenAIRE

    Kornør, Hege; Bøe, Tormod

    2011-01-01

    - Beskrivelse. ADHD-RS-IV Skole er et spørreskjema som skal fylles ut av lærere eller førskolelærere for å fange opp ADHD-symptomer hos barn og ungdom. Spørreskjemaet har 18 ledd med fire svaralternativer. Det tar under 20 minutter å fylle ut. Hovedskalaen og de to delskalaene skåres ved å summere enkeltskårer. Kompetansekrav for bruk av ADHD-RS-IV inkluderer generell opplæring i testbruk, samt yrkesstatus som psykolog, lege, annet helsepersonell med utdanning på mastergradsnivå, spesialpe...

  11. Måleegenskaper ved den norske versjonen av ADHD Rating Scale – IV Hjemmeversjon (ADHD-RS-IV Hjemme)

    OpenAIRE

    Kornør, Hege; Bøe, Tormod

    2011-01-01

    - Beskrivelse. ADHD-RS-IV Hjemme er et spørreskjema som skal fylles ut av mor, far, verge eller besteforeldre for å fange opp ADHD-symptomer hos barn og ungdom. Spørreskjemaet har 18 ledd med fire svaralternativer. Det tar under 20 minutter å fylle ut. Hovedskalaen og de to delskalaene skåres ved å summere enkeltskårer. Kompetansekrav for bruk av ADHD-RS-IV inkluderer generell opplæring i testbruk, samt yrkesstatus som psykolog, lege, annet helsepersonell med utdanning på ...

  12. RP-HPLCdetermination of ginsenosides RG1 and RB1 in Panax ...

    African Journals Online (AJOL)

    Y Liu, Q He, D Liu, W Wan, X Liu, C Wen, W Fang, W Zhou, Z Xia ... RP-HPLC method is adopted, column used is a ZOBAX SB-C18 column (4.6 mm × 250 mnl, 5 μm), mobile phase A is water, and B is acetonitrile, gradient elution conditions are: 0~20 min (A:B 20:80), 20~60 min (A:B 20~35: 80~65); and detection ...

  13. Leguay Jean-Pierre, 1999, La pollution au Moyen-Âge, Edition Jean-Paul Gisserot, Paris

    OpenAIRE

    Rousseau, Sandrine

    2004-01-01

    Si vous aviez du Moyen-Âge la vision qu’en donnent certaines gravures : une belle princesse au bras d’un preux chevalier, Jean-Pierre Leguay, professeur d’histoire médiévale à l’université de Haute-Normandie, risque de vous surprendre. En effet, son ouvrage, La pollution au Moyen-Âge modifiera sans doute cette vision idyllique. Pour commencer, sachez que la princesse et son preux chevalier ont les pieds dans la boue, une boue composée de la fange, d’excréments humains, de déchets des bouchers...

  14. Complementary microanalysis of Zn, Mn and Fe in the chelicera of spiders and scorpions using scanning MeV-ion and electron microprobes

    International Nuclear Information System (INIS)

    Schofield, R.; Lefevre, H.; Shaffer, M.

    1989-01-01

    Energy-loss scanning transmission ion microscopy (ELSTIM or just STIM), PIXE and electron microprobe techniques are used to investigate certain minor element accumulations in a few spiders and scorpions. STIM and PIXE are used to survey the unsectioned specimens, while electron microprobe techniques are used for higher resolution investigations of several sections of the specimens. Concentration values measured using STIM and PIXE are found to be in satisfactory agreement with those measured using electron probe microanalysis. A garden spider Araneous diadematus is found to contain high concentrations of zinc in a thin layer near the surface of its fangs (reaching 23% of dry weight), and manganese in its marginal teeth (about 5% of dry weight). A wolf spider Alopecosa kochi is found to have similar concentrations of zinc in a layer near the surface of it's fang, and concentrations of manganese reaching 1.5% in a layer beneath the zinc containing layer. A scorpion Centruroides sp. is found to contain high concentrations of iron (reaching 8%) and zinc (reaching 24%) in the tips of teeth on the cheliceral fingers, and manganese (about 5%) in the stinger. The hypothesis that these elements simply harden the cuticle does not appear to explain their segregation patterns. (orig.)

  15. The breeding behaviour, advertisement call and tadpole of Limnonectes dabanus (Anura: Dicroglossidae).

    Science.gov (United States)

    Rowley, Jodi J L; Le, Duong Thi Thuy; Hoang, Huy Duc; Altig, Ronald

    2014-11-04

    Fanged frogs (Limnonectes) are a group of dicroglossid frogs from Asia that often have reversed sexual dimorphism with larger males. Limnonectes dabanus is a poorly known species of fanged frog from forested habitats in southern Vietnam and eastern Cambodia. Adult males exhibit an extreme degree of megacephaly and possess bizarre head ornamentation. L. dabanus breeds in shallow, non-flowing or very slow-flowing pools, puddles, and drainage ditches. Eggs are laid as a widely spaced array, and the larvae have a morphology typical of pond-dwelling tadpoles. Although males of the species lack vocal sacs, they produce a low-pitched (0.4-0.6 kHz), single-note advertisement call that sounds like a drop of water falling into water. Given the spacing of calling males, presence of multiple females near breeding sites, and reversed sexual dimorphism, the mating system of L. dabanus may be an example of resource-defense polygyny, and the massive head of the male is likely used in male combat.

  16. A Review and Database of Snake Venom Proteomes.

    Science.gov (United States)

    Tasoulis, Theo; Isbister, Geoffrey K

    2017-09-18

    Advances in the last decade combining transcriptomics with established proteomics methods have made possible rapid identification and quantification of protein families in snake venoms. Although over 100 studies have been published, the value of this information is increased when it is collated, allowing rapid assimilation and evaluation of evolutionary trends, geographical variation, and possible medical implications. This review brings together all compositional studies of snake venom proteomes published in the last decade. Compositional studies were identified for 132 snake species: 42 from 360 (12%) Elapidae (elapids), 20 from 101 (20%) Viperinae (true vipers), 65 from 239 (27%) Crotalinae (pit vipers), and five species of non-front-fanged snakes. Approximately 90% of their total venom composition consisted of eight protein families for elapids, 11 protein families for viperines and ten protein families for crotalines. There were four dominant protein families: phospholipase A₂s (the most common across all front-fanged snakes), metalloproteases, serine proteases and three-finger toxins. There were six secondary protein families: cysteine-rich secretory proteins, l-amino acid oxidases, kunitz peptides, C-type lectins/snaclecs, disintegrins and natriuretic peptides. Elapid venoms contained mostly three-finger toxins and phospholipase A₂s and viper venoms metalloproteases, phospholipase A₂s and serine proteases. Although 63 protein families were identified, more than half were present in <5% of snake species studied and always in low abundance. The importance of these minor component proteins remains unknown.

  17. Utilization of statistical table for waves in North-west Pacific Ocean and a long-term estimation on hull responses; Seihoku Taiheiyo haro tokeihyo no riyo to sentai oto choki yosoku

    Energy Technology Data Exchange (ETDEWEB)

    Shinkai, A [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1997-10-01

    Designing a vessel to sail oceans for an extended period of time requires statistical estimation on different hull responses to waves. To meet the requirement, it is necessary to accurately identify hydrographic conditions (particularly waves) which are considered to be encountered by the vessel. This paper makes clear the statistical characteristics of the wave statistics table presented by Fang et al, and compares them with other processes for discussion. This statistics collection is based on data collected in China, Hong Kong and Japan, including those collected in the Sea of Japan, the Yellow Sea, the North Sea, the East China Sea and the South China Sea. It was found that these data provide results slightly lower than the long-term estimation values derived from data of the global wave statistics (GWS) prepared by Hogben et al. The cause for this was found attributable to the format of the statistical data, especially setting of wave height classes. However, since the data provided by Fang et al include items of detailed information on small sea areas near the Chinese coast lines, the data are thought to provide useful information source in investigating long-term hull response characteristics relative to spatial spread of the sea areas in the North-west Pacific Ocean. 15 refs., 5 figs., 2 tabs.

  18. Grooves to tubes: evolution of the venom delivery system in a Late Triassic "reptile"

    Science.gov (United States)

    Mitchell, Jonathan S.; Heckert, Andrew B.; Sues, Hans-Dieter

    2010-12-01

    Venom delivery systems occur in a wide range of extant and fossil vertebrates and are primarily based on oral adaptations. Teeth range from unmodified (Komodo dragons) to highly specialized fangs similar to hypodermic needles (protero- and solenoglyphous snakes). Developmental biologists have documented evidence for an infolding pathway of fang evolution, where the groove folds over to create the more derived condition. However, the oldest known members of venomous clades retain the same condition as their extant relatives, resulting in no fossil evidence for the transition. Based on a comparison of previously known specimens with newly discovered teeth from North Carolina, we describe a new species of the Late Triassic archosauriform Uatchitodon and provide detailed analyses that provide evidence for both venom conduction and document a complete structural series from shallow grooves to fully enclosed tubular canals. While known only from teeth, Uatchitodon is highly diagnostic in possessing compound serrations and for having two venom canals on each tooth in the dentition. Further, although not a snake, Uatchitodon sheds light on the evolutionary trajectory of venom delivery systems in amniotes and provide solid evidence for venom conduction in archosaur-line diapsids.

  19. [A study of the sexual art of having intercourse with several young virgins in traditional Chinese medicine].

    Science.gov (United States)

    Yan, Shanzhao

    2002-06-01

    The emergency treatments for the damage and bleeding of the vagina, and the sharp pubic pain of young virgins which were caused occurred by the sexual art, were recorded in traditional medicine books, such as the "Ji yan fang" and others. It is a fact that in ancient China some people used the sexual art of having intercourse with several young virgins at the same time in order to increase their health and keep perpetual youth and longevity. The famous traditional general-medical book, "qian jin yao fang" recommended that method to rich persons too. It is supposed that the beginning of the sexual art of having intercourse with several young virgins traces back to the times of Emperor Hanwu , but it seems to have disappeared from the historical stage in the Song period. On the other hand, the criticisms from the traditional medicine books and the secret languages of internal alchemy used for the Taoist sacred books show that the sexual art of having intercourse with several young virgins was still going on behind the scene in the Ming and Qing periods. Even if we consider the historical changes of ethics and mortality, we now cannot but criticize this behavior of abusing juveniles for the sexual art.

  20. Climate reconstructions from tree-ring widths for the last 850 years in Northern Poland

    Science.gov (United States)

    Heinrich, Ingo; Knorr, Antje; Heußner, Karl-Uwe; Wazny, Tomasz; Slowinski, Michal; Helle, Gerhard; Simard, Sonia; Scharnweber, Tobias; Buras, Allan; Beck, Wolfgang; Wilmking, Martin; Brauer, Achim

    2015-04-01

    Tree-ring based temperature reconstructions form the scientific backbone of the current debate over global change, and they are the major part of the palaeo data base used for the IPCC report. However, long temperature reconstructions derived from temperate lowland trees growing well within their distributional limits in central Europe are not part of the IPCC report, which is an essential gap in the international data base. It appears that dendroclimatological analysis at temperate lowland sites was so far difficult to perform mainly for three reasons: diffuse climate-growth relationships, the lack of long chronologies due to absence of sufficient numbers of long-living trees and the potential loss of low-frequency signals due to the short length of the sample segments. We present two robust multi-centennial reconstructions of winter temperatures and summer precipitation based on pine and oak tree-ring widths chronologies from northern Poland, where so far no long tree-ring based reconstructions were available. We compared the new records with global, hemispherical and regional reconstructions, and found good agreement with some of them. In comparison, the winter temperature of our reconstruction, however, did not indicate any modern warming nor did the summer precipitation reconstruction suggest any modern 20th century changes. In a second step, we measured cell structures and developed chronologies of parameters such as cell wall thickness and cell lumen area. We used our new method (Liang et al. 2013a,b) applying confocal laser scanning microscopy to increment core surfaces for efficient histometric analyses. We focused on samples covering the last century because meteorological data necessary for calibration studies were available for direct comparisons. It was demonstrated that the correlations with climate were strong and different from those found for tree-ring widths (e.g., N-Poland oak-vessel-lumen-area-chronology with previous September-to-December mean

  1. Diffusive exchange of trace elements between basaltic-andesite and dacitic melt: Insights into potential metal fractionation during magma mixing

    Science.gov (United States)

    Fiege, A.; Ruprecht, P.; Simon, A. C.; Holtz, F.

    2017-12-01

    Mafic magma recharge is a common process that triggers physical and chemical mixing in magmatic systems and drives their evolution, resulting in, e.g., hybridization and volcanic eruptions. Once magma-magma contact is initiated, rapid heat-flux commonly leads to the formation of a cooling-induced crystal mush on the mafic side of the interface. Here, on a local scale (µm to cm), at the magma-magma interface, melt-melt diffusive exchange is required to approach equilibrium. Significant chemical potential gradients drive a complex, multi-element mass flux between the two systems (Liang, 2010). This diffusive-equilibration often controls crystal dissolution rates within the boundary layers and, thus, the formation of interconnected melt or fluid networks. Such networks provide important pathways for the transport of volatiles and trace metals from the mafic recharge magma to the felsic host magma, where the latter may feed volcanic activities and ore deposits. While major element diffusion in silicate melts is mostly well understood, even in complex systems, the available data for many trace element metals are limited (Liang, 2010; Zhang et al., 2010). Differences in diffusivity in a dynamic, mixing environment can cause trace element fractionation, in particular during crystallization and volatile exsolution and separation. This may affect trace element signatures in phenocrysts and magmatic volatile phases that can form near a magma-magma boundary. As a result, the chemistry of volcanic gases and magmatic-hydrothermal ore deposits may be partially controlled by such mixing phenomena. We performed melt-melt diffusion-couple experiments at 150 MPa, 1100°C, FMQ, FMQ+1 and FMQ+3 (FMQ: fayalite-magnetite-quartz oxygen fugacity buffer). Hydrated, sulfur-bearing cylinders of dacite and basaltic andesite were equilibrated for up to 20 h. Major and trace element gradients were measured by using laser-ablation ICP-MS and electron microprobe analyses. The results we will

  2. The Watinglo mandible: a second terminal Pleistocene Homo sapiens fossil from tropical Sahul with a test on existing models for the human settlement of the region.

    Science.gov (United States)

    Bulbeck, D; O'Connor, S

    2011-02-01

    This paper analyses a fossil human mandible, dated to circa 10ka, from Watinglo rockshelter on the north coast of Papua New Guinea. The fossil is metrically and morphologically similar to male mandibles of recent Melanesians and Australian Aborigines. It is distinguished from Kow Swamp and Coobool Creek male mandibles (Murray Valley, terminal Pleistocene) by being smaller and having different shape characteristics, as well as smaller teeth and a slower rate of tooth wear. It pairs with the Liang Lemdubu female (Late Glacial Maximum, Aru Islands) in suggesting that the morphology of the terminal Pleistocene inhabitants of tropical Sahul was gracile compared to their contemporaries within the southern Murray drainage. An explanatory scenario for this morphological contrast is developed in the context of the Homo sapiens early fossil record, Australasian mtDNA evidence, terminal Pleistocene climatic variation, and the possibility of multiple entry points into Sahul. Copyright © 2010 Elsevier GmbH. All rights reserved.

  3. Effect of petroleum pollution tax on pollution control and the economy of Taiwan

    International Nuclear Information System (INIS)

    Chi-Yuan Liang.

    1992-01-01

    The objective of this paper is to employ the modified Jorgenson-Liang model (1985), which is a dynamic thirty-sector energy economic model of Taiwan, to analyze the effect of petroleum pollution tax on pollution control, oil consumption, output prices and cost structure in Taiwan's industrial sectors during 1990-1995. The conclusion of this paper is that to levy petroleum pollution tax will result in a significant decrease of consumption on oil products and air pollution. However it has only mild impact on the sectoral output prices and cost structure. And hence the implementation of petroleum pollution tax, will not only be effective in reducing the air pollution emission of oil products but also economically feasible. 4 refs., 2 tabs

  4. Reconstructing the cosmic expansion history up to redshift z=6.29 with the calibrated gamma-ray bursts

    International Nuclear Information System (INIS)

    Wei, Hao; Nan Zhang, Shuang

    2009-01-01

    Recently, Gamma-Ray Bursts (GRBs) were proposed to be a complementary cosmological probe to type Ia supernovae (SNIa). GRBs have been advocated to be standard candles since several empirical GRB luminosity relations were proposed as distance indicators. However, there is a so-called circularity problem in the direct use of GRBs. Recently, a new idea to calibrate GRBs in a completely cosmology independent manner has been proposed, and the circularity problem can be solved. In the present work, following the method proposed by Liang et al., we calibrate 70 GRBs with the Amati relation using 307 SNIa. Then, following the method proposed by Shafieloo et al., we smoothly reconstruct the cosmic expansion history up to redshift z=6.29 with the calibrated GRBs. We find some new features in the reconstructed results. (orig.)

  5. Patenting and Innovation in China: Incentives, Policy, and Outcomes

    Science.gov (United States)

    2015-01-01

    limited at 30,000 yuan. See: Kriegel,  J. (2012). Strategies to leverage Chinese patent subsidies Intellectual Property  Magazine .   26 A patent claim...2012). Strategies to leverage Chinese patent subsidies Intellectual Property  Magazine .  Kumar, N. (2003). "Intellectual property rights, technology and...innovation in China: the role of patents in  biotechnology  and  pharmaceutical industries, Edward Elgar.  Liang, M. (2011). "Chinese Patent Quality: Running

  6. Speleothem carbon isotopes in the tropics: a proxy for vegetation and what they reveal about the demise of Homo floresiensis

    Science.gov (United States)

    Scroxton, N.; Gagan, M. K.; Ayliffe, L. K.; Hellstrom, J.; Cheng, H.; Edwards, R.; Zhao, J.; Hantoro, W. S.; Rifai, H.; Scott-Gagan, H.; Cowley, J. A.; Suwargadi, B. W.

    2013-12-01

    Most long-term speleothem climate records focus on δ18O (Cruz Jr. et al. 2005, Wang et al. 2005, Meckler et al. 2012, Carolin et al. 2013). In tropical regions, where temperature variability is relatively small, speleothem δ18O serves as a proxy for precipitation amount. On orbital timescales, changes in moisture source, sea level and global ice volume also influence speleothem δ18O. As both δ18O and δ13C are measured simultaneously, a wealth of potential paleoclimatic information from the δ13C records for numerous sites awaits publication. However, δ13C is less well understood as an environmental proxy, and a simple control and explanation may not be forthcoming. We present a new 92,000-year long speleothem δ13C record for Liang Luar cave in Flores, Indonesia. Here, δ13C acts as a proxy for soil CO2 production above the cave, which is strongly linked to vegetative changes. Since vegetation and soil CO2 production are closely linked to a climatic control, changes in speleothem δ13C can be considered an environmental response to climate change. The Liang Luar δ13C record mainly tracks the δ18O, indicating close affiliation between vegetation and climate. Peak vegetation cover and soil activity (lower δ13C) occur in the early Holocene. The Last Glacial Maximum does not have notably higher δ13C than Isotope Stages 3 and 5a. δ13C variability in the glacial is much higher than that in the Holocene. Differences between the δ13C and δ18O records indicate periods of vegetative change without a climatic cause. The largest increase in δ13C (8‰) during the last 90kyr occurred at 68kyr BP. This anomalous δ13C excursion represents a major loss of vegetation around Liang Luar. The last surviving non-human member of the Homo genus: Homo floresiensis, disappeared from the stratigraphic record in nearby Liang Bua cave between 17 and 10kyr BP (Roberts et al. 2009). The cause of the disappearance, (e.g. climate change, volcanic catastrophe or human competition

  7. History Made for Tomorrow: Hakka Tulou

    Directory of Open Access Journals (Sweden)

    Richard M. Yelland

    2013-11-01

    Full Text Available The documentary film, History Made for Tomorrow: Hakka Tulou was an October 2010 release by History Channel International. This film is an in-depth study on the green building techniques and sustainable lifestyle of the Hakka people of Southern China with a focus on the ancient Tulou rammed earth structures. The television program follows West Virginia University research professor, Ruifeng Liang, as he initiates scientific studies to back claims that the rammed earth Tulou structures are “the greenest buildings in the world”, and Canadian architect, Jorg Ostrowski, of Autonomous Sustainable Housing Inc., who has been researching the ecological footprint of Hakka communities since August 2007, to promote them as “eco-villages” of best practices for planet Earth’s sustainability. The author is credited as Director, Writer, and Producer of this film. This paper is based on the script of the production.

  8. Stability analysis and time-step limits for a Monte Carlo Compton-scattering method

    International Nuclear Information System (INIS)

    Densmore, Jeffery D.; Warsa, James S.; Lowrie, Robert B.

    2010-01-01

    A Monte Carlo method for simulating Compton scattering in high energy density applications has been presented that models the photon-electron collision kinematics exactly [E. Canfield, W.M. Howard, E.P. Liang, Inverse Comptonization by one-dimensional relativistic electrons, Astrophys. J. 323 (1987) 565]. However, implementing this technique typically requires an explicit evaluation of the material temperature, which can lead to unstable and oscillatory solutions. In this paper, we perform a stability analysis of this Monte Carlo method and develop two time-step limits that avoid undesirable behavior. The first time-step limit prevents instabilities, while the second, more restrictive time-step limit avoids both instabilities and nonphysical oscillations. With a set of numerical examples, we demonstrate the efficacy of these time-step limits.

  9. The Homo floresiensis Controversy

    Directory of Open Access Journals (Sweden)

    COLIN GROVES

    2007-12-01

    Full Text Available A completely new and unexpected quasi human species, Homo floresiensis, nicknamed the Hobbit, was described in 2004 from Liang Bua, a cave in Flores. Like many important new contributions to the human fossil record in the past, many commentators refused to believe that a new species had been discovered, and the type specimen was interpreted as a pathological modern human, usually as a microcephalic dwarf. There is no substance to these claims: close analysis shows that Homo floresiensis is not only a genuinely new species, but that its closest affinities lie with Plio-Pleistocene African species such as Homo habilis, so that it documents an earlier dispersal of hominins from Africa and had hitherto been suspected.

  10. The plastid genome of the red macroalga Grateloupia taiwanensis (Halymeniaceae.

    Directory of Open Access Journals (Sweden)

    Michael S DePriest

    Full Text Available The complete plastid genome sequence of the red macroalga Grateloupia taiwanensis S.-M.Lin & H.-Y.Liang (Halymeniaceae, Rhodophyta is presented here. Comprising 191,270 bp, the circular DNA contains 233 protein-coding genes and 29 tRNA sequences. In addition, several genes previously unknown to red algal plastids are present in the genome of G. taiwanensis. The plastid genomes from G. taiwanensis and another florideophyte, Gracilaria tenuistipitata var. liui, are very similar in sequence and share significant synteny. In contrast, less synteny is shared between G. taiwanensis and the plastid genome representatives of Bangiophyceae and Cyanidiophyceae. Nevertheless, the gene content of all six red algal plastid genomes here studied is highly conserved, and a large core repertoire of plastid genes can be discerned in Rhodophyta.

  11. The mitochondrial genome of Grateloupia taiwanensis (Halymeniaceae, Rhodophyta) and comparative mitochondrial genomics of red algae.

    Science.gov (United States)

    DePriest, Michael S; Bhattacharya, Debashish; López-Bautista, Juan M

    2014-10-01

    Although red algae are economically highly valuable for their gelatinous cell wall compounds as well as being integral parts of marine benthic habitats, very little genome data are currently available. We present mitochondrial genome sequence data from the red alga Grateloupia taiwanensis S.-M. Lin & H.-Y. Liang. Comprising 28,906 nucleotide positions, the mitochondrial genome contig contains 25 protein-coding genes and 24 transfer RNA genes. It is highly similar to other red algal genomes in gene content as well as overall structure. An intron in the cox1 gene was found to be shared by G. taiwanensis and Grateloupia angusta (Okamura) S. Kawaguchi & H. W. Wang. We also used whole-genome alignments to compare G. taiwanensis to different groups of red algae, and these results are consistent with the currently accepted phylogeny of Rhodophyta. © 2014 Marine Biological Laboratory.

  12. The Plastid Genome of the Red Macroalga Grateloupia taiwanensis (Halymeniaceae)

    Science.gov (United States)

    DePriest, Michael S.; Bhattacharya, Debashish; López-Bautista, Juan M.

    2013-01-01

    The complete plastid genome sequence of the red macroalga Grateloupia taiwanensis S.-M.Lin & H.-Y.Liang (Halymeniaceae, Rhodophyta) is presented here. Comprising 191,270 bp, the circular DNA contains 233 protein-coding genes and 29 tRNA sequences. In addition, several genes previously unknown to red algal plastids are present in the genome of G. taiwanensis. The plastid genomes from G. taiwanensis and another florideophyte, Gracilaria tenuistipitata var. liui, are very similar in sequence and share significant synteny. In contrast, less synteny is shared between G. taiwanensis and the plastid genome representatives of Bangiophyceae and Cyanidiophyceae. Nevertheless, the gene content of all six red algal plastid genomes here studied is highly conserved, and a large core repertoire of plastid genes can be discerned in Rhodophyta. PMID:23894297

  13. Application of generalized estimating equations to a study in vitro of radiation sensitivity

    International Nuclear Information System (INIS)

    Cologne, J.B.; Carter, R.L.; Fujita, Shoichiro; Ban, Sadayuki.

    1993-08-01

    We describes an application of the generalized estimating equation (GEE) method (Liang K-Y, Zeger SL: Longitudinal data analysis using generalized linear models. Biometrika 73:13-22, 1986) for regression analyses of correlated Poisson data. As an alternative to the use of an arbitrarily chosen working correlation matrix, we demonstrate the use of GEE with a reasonable model for the true covariance structure among repeated observations within individuals. We show that, under such a split-plot design with large clusters, the asymptotic relative efficiency of GEE with simple (independence or exchangeable) working correlation matrices is rather low. We also illustrate the use of GEE with an empirically estimated model for overdispersion in a large study of radiation sensitivity where cluster size is small and a simple working correlation structure is sufficient. We conclude by summarizing issues and needs for further work concerning efficiency of the GEE parameter estimates in practice. (author)

  14. Resonance Raman spectra of organic molecules absorbed on inorganic semiconducting surfaces: Contribution from both localized intramolecular excitation and intermolecular charge transfer excitation

    International Nuclear Information System (INIS)

    Ye, ChuanXiang; Zhao, Yi; Liang, WanZhen

    2015-01-01

    The time-dependent correlation function approach for the calculations of absorption and resonance Raman spectra (RRS) of organic molecules absorbed on semiconductor surfaces [Y. Zhao and W. Z. Liang, J. Chem. Phys. 135, 044108 (2011)] is extended to include the contribution of the intermolecular charge transfer (CT) excitation from the absorbers to the semiconducting nanoparticles. The results demonstrate that the bidirectionally interfacial CT significantly modifies the spectral line shapes. Although the intermolecular CT excitation makes the absorption spectra red shift slightly, it essentially changes the relative intensities of mode-specific RRS and causes the oscillation behavior of surface enhanced Raman spectra with respect to interfacial electronic couplings. Furthermore, the constructive and destructive interferences of RRS from the localized molecular excitation and CT excitation are observed with respect to the electronic coupling and the bottom position of conductor band. The interferences are determined by both excitation pathways and bidirectionally interfacial CT

  15. Pedestrian Dharma: Slowness and Seeing in Tsai Ming-Liang’s Walker

    Directory of Open Access Journals (Sweden)

    Teng-Kuan Ng

    2018-06-01

    Full Text Available This paper studies the ways that Walker, a short film by the Malaysian-Taiwanese auteur Tsai Ming-Liang, visualizes the relationship between Buddhism and modernity. Via detailed film analysis as well as attention to sources in premodern Buddhist traditions, this paper argues that its filmic performance of Zen walking meditation serves two functions: To present slowness and simplicity as prophetic counterpoints against the dizzying excesses of the contemporary metropolis; and to offer contemplative attentiveness as a therapeutic resource for life in the modern world. By instantiating and cultivating critical shifts in viewerly perspective in the manner of Buddhist ritual practice, Walker invites us to envision how a place of frenetic distraction or pedestrian mundaneness might be transfigured into a site of beauty, wonder, and liberation.

  16. Gut microbiota–derived short-chain fatty acids and kidney diseases

    Directory of Open Access Journals (Sweden)

    Li L

    2017-12-01

    Full Text Available Lingzhi Li, Liang Ma, Ping Fu Kidney Research Institute, Department of Nephrology, West China Hospital of Sichuan University, Chengdu 610041, China Abstract: Gut microbiota and its metabolites play pivotal roles in host physiology and pathology. Short-chain fatty acids (SCFAs, as a group of metabolites, exert positive regulatory effects on energy metabolism, hormone secretion, immune inflammation, hypertension, and cancer. The functions of SCFAs are related to their activation of transmembrane G protein-coupled receptors and their inhibition of histone acetylation. Though controversial, growing evidence suggests that SCFAs, which regulate inflammation, oxidative stress, and fibrosis, have been involved in kidney disease through the activation of the gut–kidney axis; however, the molecular relationship among gut microbiota–derived metabolites, signaling pathways, and kidney disease remains to be elucidated. This review will provide an overview of the physiology and functions of SCFAs in kidney disease. Keywords: gut microbiome, short-chain fatty acids, kidney diseases, gut–kidney axis

  17. Band Alignment for Rectification and Tunneling Effects in Al2O3 Atomic-Layer-Deposited on Back Contact for CdTe Solar Cell.

    Science.gov (United States)

    Su, Yantao; Xin, Chao; Feng, Yancong; Lin, Qinxian; Wang, Xinwei; Liang, Jun; Zheng, Jiaxin; Lin, Yuan; Pan, Feng

    2016-10-11

    The present work intends to explain why ultrathin Al 2 O 3 atomic-layer-deposited (ALD) on the back contact with rectification and tunneling effects can significantly improve the performance of CdTe solar cells in our previous work [ Liang , J. ; et al. Appl. Phys. Lett. 2015 , 107 , 013907 ]. Herein, we further study the mechanism through establishing the interfacial energy band diagram configuration of the ALD Al 2 O 3 /Cu x Te by experiment of X-ray photoelectron spectroscopy and first-principles calculations and conclude to find the band alignment with optimized layer thickness (about 1 nm ALD Al 2 O 3 ) as the key factor for rectification and tunneling effects.

  18. KEJADIAN KOLONI JAMUR PADA PENDERITA OTORE DENGAN BERBAGAI PENYEBAB DI POLIKLINIK THT RUMAH SAKIT PENDIDIKAN UNHAS

    Directory of Open Access Journals (Sweden)

    Sedjawidada R

    2014-09-01

    Full Text Available Telah dilakukan penelitian survey dengan pendekatan deskriptif tentang Kejadian Koloni Jamur pada Penderita Otore dengan Berbagai Penyebab di Poliklinik THT Rumah Sakit Pendidikan Unhas. Sampel yang diteliti adalah eksudat yang diambil dari liang telinga luar setiap telinga yang menderita Otitis eksterna superfisialis basah, Otitis media supuratif akut perforasi, Otitis media supuratif kronik benigna aktif. Dari total sampel sejumlah 103 yang dipilih secara consecutive sampling didapatkan adanya koloni jamur pada otitis eksterna superfisialis basah sebesar 57,8% dengan jenis jamur Aspergillus niger 17,9%, Candida albicans 13,3% dan Aspergillus fumigatus 8,9%. Koloni jamur pada OMSA perforasi sebesar 44,4% dengan jenis jamur Aspergillus fumigatus 11,1%, Candida albicans 11,1% dan Aspergillus niger 5,6%. Koloni jamur pada OMSK benigna aktif sebesar 25% dengan jenis jamur Apergillus fumigatus 17,5%, Aspergillus niger 2,5% dan Candida albicans 2,5%.[MEDICINA 2009;40:21-6].

  19. Study on calculation model of onset of nucleate boiling in narrow channels

    International Nuclear Information System (INIS)

    Zhang Ming; Zhou Tao; Sheng Cheng; Fu Tao; Xiao Zejun

    2011-01-01

    In the reactor engineering, narrow channels was used widely for its high power density, exceptional heat transfer and actual engineering requirements. The point of Onset of Nucleate Boiling (ONB) is the key point of boiling heat transfer in narrow channels. The point of ONB can directly influence the following flow and heat transfer characteristics in the reactor. Due to the special structure and complexity flow, the point of ONB in narrow channels are effected by many factors, which characteristics are not understood completely yet. Using B and R model, Su Shun-yu model, Pan Liang-ming model and Yang Rui-chang model, the heat flux of onset of nucleate boiling is compared and analyzed by taking water as the medium . And then the relationships of the heat flux with pressure, mass flow and wall temperature are obtained. Based on the differences of each model, the mechanisms for the main influence factors are suggested. (authors)

  20. Academic origins and characteristics of the Chinese stylistic restoration

    Directory of Open Access Journals (Sweden)

    Xi Chen

    2016-09-01

    Full Text Available The conservation practice in China, termed “Chinese stylistic restoration” in this study, has been influenced by the traditional Chinese philosophy and construction principles, the modern Chinese conservation theory of Liang Sicheng and Liu Dunzhen, and Western and international theories and policies concerning conservation. This study uses three case studies, namely, Shanghai Zhenru Temple, Jianfu Palace Garden, and Angkor Wat Chau Say Tevoda Temple, to demonstrate the main characteristics of the Chinese stylistic restoration, including its emphasis on style over authenticity, pursuit of a gestalt form, and flexible attitude toward reconstruction. Accordingly, these practices have shaped the current Chinese conservation theory as reflected in the case studies reported in “Principles for the Conservation of Heritage Sites in China” and the Qufu Declaration.

  1. Computer simulation as an important approach to explore language universal. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

    Science.gov (United States)

    Lu, Qian

    2017-07-01

    Exploring language universal is one of the major goals of linguistic researches, which are largely devoted to answering the ;Platonic questions; in linguistics, that is, what is the language knowledge, how to get and use this knowledge. However, if solely guided by linguistic intuition, it is very difficult for syntactic studies to answer these questions, or to achieve abstractions in the scientific sense. This suggests that linguistic analyses based on the probability theory may provide effective ways to investigate into language universals in terms of biological motivations or cognitive psychological mechanisms. With the view that ;Language is a human-driven system;, Liu, Xu & Liang's review [1] pointed out that dependency distance minimization (DDM), which has been corroborated by big data analysis of corpus, may be a language universal shaped in language evolution, a universal that has profound effect on syntactic patterns.

  2. LB1 and LB6 Homo floresiensis are not modern human (Homo sapiens) cretins.

    Science.gov (United States)

    Brown, Peter

    2012-02-01

    Excavations in the late Pleistocene deposits at Liang Bua cave, Flores, have uncovered the skeletal remains of several small-bodied and small-brained hominins in association with stone artefacts and the bones of Stegodon. Due to their combination of plesiomorphic, unique and derived traits, they were ascribed to a new species, Homo floresiensis, which, along with Stegodon, appears to have become extinct ∼17 ka (thousand years ago). However, recently it has been argued that several characteristics of H. floresiensis were consistent with dwarfism and evidence of delayed development in modern human (Homo sapiens) myxoedematous endemic (ME) cretins. This research compares the skeletal and dental morphology in H. floresiensis with the clinical and osteological indicators of cretinism, and the traits that have been argued to be associated with ME cretinism in LB1 and LB6. Contrary to published claims, morphological and statistical comparisons did not identify the distinctive skeletal and dental indicators of cretinism in LB1 or LB6 H. floresiensis. Brain mass, skeletal proportions, epiphyseal union, orofacial morphology, dental development, size of the pituitary fossa and development of the paranasal sinuses, vault bone thickness and dimensions of the hands and feet all distinguish H. floresiensis from modern humans with ME cretinism. The research team responsible for the diagnosis of ME cretinism had not examined the original H. floresiensis skeletal materials, and perhaps, as a result, their research confused taphonomic damage with evidence of disease, and thus contained critical errors of fact and interpretation. Behavioural scenarios attempting to explain the presence of cretinous H. sapiens in the Liang Bua Pleistocene deposits, but not unaffected H. sapiens, are both unnecessary and not supported by the available archaeological and geochronological evidence from Flores. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

  3. Ionospheric Electron Heating Associated With Pulsating Auroras: Joint Optical and PFISR Observations

    Science.gov (United States)

    Liang, Jun; Donovan, E.; Reimer, A.; Hampton, D.; Zou, S.; Varney, R.

    2018-05-01

    In a recent study, Liang et al. (2017, https://doi.org/10.1002/2017JA024127) repeatedly identified strong electron temperature (Te) enhancements when Swarm satellites traversed pulsating auroral patches. In this study, we use joint optical and Poker Flat Incoherent Scatter Radar (PFISR) observations to further investigate the F region plasma signatures related to pulsating auroras. On 19 March 2015 night, which contained multiple intervals of pulsating auroral activities, we identify a statistical trend, albeit not a one-to-one correspondence, of strong Te enhancements ( 500-1000 K) in the upper F region ionosphere during the passages of pulsating auroras over PFISR. On the other hand, there is no discernible and repeatable density enhancement in the upper F region during pulsating auroral intervals. Collocated optical and NOAA satellite observations suggest that the pulsating auroras are composed of energetic electron precipitation with characteristic energy >10 keV, which is inefficient in electron heating in the upper F region. Based upon PFISR observations and simulations from Liang et al. (2017) model, we propose that thermal conduction from the topside ionosphere, which is heated by precipitating low-energy electrons, offers the most likely explanation for the observed electron heating in the upper F region associated with pulsating auroras. Such a heating mechanism is similar to that underlying the "stable auroral red arcs" in the subauroral ionosphere. Our proposal conforms to the notion on the coexistence of an enhanced cold plasma population and the energetic electron precipitation, in magnetospheric flux tubes threading the pulsating auroral patch. In addition, we find a trend of enhanced ion upflows during pulsating auroral intervals.

  4. Causal relationship between the global foreign exchange market based on complex networks and entropy theory

    International Nuclear Information System (INIS)

    Cao, Guangxi; Zhang, Qi; Li, Qingchen

    2017-01-01

    Highlights: • Mutual information is used as the edge weights of nodes instead of PCC, which overcomes the shortcomings of linear correlation functions. • SGD turns into a new cluster center and gradually becomes a point connecting the Asian and European clusters during and after the US sub-prime crisis. • Liang's entropy theory, which has not been adopted before in the global foreign exchange market, is considered. - Abstract: The foreign exchange (FX) market is a typical complex dynamic system under the background of exchange rate marketization reform and is an important part of the financial market. This study aims to generate an international FX network based on complex network theory. This study employs the mutual information method to judge the nonlinear characteristics of 54 major currencies in international FX markets. Through this method, we find that the FX network possesses a small average path length and a large clustering coefficient under different thresholds and that it exhibits small-world characteristics as a whole. Results show that the relationship between FX rates is close. Volatility can quickly transfer in the whole market, and the FX volatility of influential individual states transfers at a fast pace and a large scale. The period from July 21, 2005 to March 31, 2015 is subdivided into three sub-periods (i.e., before, during, and after the US sub-prime crisis) to analyze the topology evolution of FX markets using the maximum spanning tree approach. Results show that the USD gradually lost its core position, EUR remained a stable center, and the center of the Asian cluster became unstable. Liang's entropy theory is used to analyze the causal relationship between the four large clusters of the world.

  5. Yi lin cuo yao(Essentials of Medical Works) and its historical materials of medical exchanges between China and Korea%朝鲜《医林撮要》所载中朝医学交流史料研究

    Institute of Scientific and Technical Information of China (English)

    梁永宣

    2001-01-01

    由朝鲜内医郑正先撰、杨礼寿校正,成书于16~17世纪时期的《医林撮要》一书,共13卷128门,它引用了大量李朝前期的朝鲜医书及当时已成书的中国医书资料,是一部非常切合临床应用的综合性方书。特别是书中所收载的“中朝质问方”和“中朝传习方”中的方剂,若干处与中国宋代医书《仁斋直指方论》等有诸多联系,是中国和朝鲜医学交流过程中的重要记录。但它与记载中朝两国政府官员之间医学质问的傅懋光《医学疑问》毫不相关。%Yi lin cuo yao,including 13 chapters and 128 categories,was written by Zheng Zhengxian and collated by Yang Lishou,both Korean imperial physicians in the 16-17th centuries.With notation of a number of the Chinese and Korean medical books and materials in the first decade of the Li dynasty,this book is a comprehensive prescription work,very useful to clinical application.Especially with several points of the formulas from Zhong chao zhi wen fang (Sino-Korean Prescriptions of Questioning) and zhong chao chuan xi fang (Sino-Korean Prescriptions of Questioning) recorded in this book connected with Ren zhai zhi zhi fang lun (Renzhai's Comprehensive Prescriptions) in the Song dynasty.This book is an important record of the exchanges on medical ideas between China and Korea.However,it has nothing to do with Yi xue yi wen (Questions on Medicine) by Fu Maoguang,which records the questions and answers between Chinese and Korean officials.

  6. A cultura organizacional: o impacto visível de uma dimensão invisível

    Directory of Open Access Journals (Sweden)

    Santos, Joana Vieira

    2010-01-01

    Full Text Available No quotidiano, muitas vezes sem que se apercebam, os sujeitos são influenciados pelas características culturais do meio em que vivem. A cultura é considerada toda a totalidade dos padrões de comportamento socialmente transmitidos, artes, crenças e muitos outros processos considerados a expressão de um determinado período, classe, comunidade ou população (Choudhry, Fang e Mohamed, 2007. Ao nível organizacional encontramos um conjunto de valores, normas e padrões de comportamento que influenciam os diversos membros. Este leque de valores varia consoante a organização, correspondendo à Cultura Organizacional. O presente artigo teórico constitui uma singela análise em torno da temática, com vista a despertar reflexão e, eventualmente, futuros estudos

  7. POSTERS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@Natural Toxins   S01 Susceptibility of Edible Bihalves to Paralytic Shellfish Poisons and Their Donor   Ya-Hui Li* , Deng-Fwu Hwang, Jou-Fang Deng, Taibei, China      S02 Food Safety of Grass Carp Bile Juice   Deng-Fwu Hwang* , Yen-Hung Yeh, Jou-Feng Deng, Taibei, China      S03 Differentiation of Muscular Proteins from Toxic and Non Toxic Puffers   Tai-Yuan Chen* , Deng-Fwu Hwang, Taibei, China      S04 Radiation Resistance of Paralytic Shellfish Poison (PSP) Toxins   Terestia P Acevedo, Philippines

  8. Evaluation of correlations of flow boiling heat transfer of R22 in horizontal channels.

    Science.gov (United States)

    Zhou, Zhanru; Fang, Xiande; Li, Dingkun

    2013-01-01

    The calculation of two-phase flow boiling heat transfer of R22 in channels is required in a variety of applications, such as chemical process cooling systems, refrigeration, and air conditioning. A number of correlations for flow boiling heat transfer in channels have been proposed. This work evaluates the existing correlations for flow boiling heat transfer coefficient with 1669 experimental data points of flow boiling heat transfer of R22 collected from 18 published papers. The top two correlations for R22 are those of Liu and Winterton (1991) and Fang (2013), with the mean absolute deviation of 32.7% and 32.8%, respectively. More studies should be carried out to develop better ones. Effects of channel dimension and vapor quality on heat transfer are analyzed, and the results provide valuable information for further research in the correlation of two-phase flow boiling heat transfer of R22 in channels.

  9. Correlation between serum interleukin-6 level and type 1 diabetes mellitus: A systematic review and meta-analysis.

    Science.gov (United States)

    Chen, Yin-Ling; Qiao, Yong-Chao; Pan, Yan-Hong; Xu, Yan; Huang, Yong-Cheng; Wang, Yin-Hui; Geng, Li-Jun; Zhao, Hai-Lu; Zhang, Xiao-Xi

    2017-06-01

    This report aimed to explore the association between the change of circulating interleukin-6 (IL-6) in patients and the development of type 1 diabetes mellitus (T1DM). Four databases (PubMed, CNKI, WanFang and Civip) were used to search and list all clinical case-control studies about serum IL-6 level in T1DM patients between Jan 1, 2000 and Aug 31, 2016. A total of 20 case-control studies with 1238 T1DM patients and 742 healthy controls were included in this study. Compared to healthy controls, the serum content of IL-6 in patients with T1DM was significantly greater (overall: SMD, 1.49; 95% CI, 1.04 to 1.93; pAmerican group (SMD, 1.68; 95% CI, 0.85-2.51; pdiabetes mellitus. Copyright © 2017. Published by Elsevier Ltd.

  10. Dampak Psikologis Tokoh Pria dan Wanita dalam Film Tangshan Da Dizhen

    Directory of Open Access Journals (Sweden)

    Andriani Sinarsih

    2015-11-01

    Full Text Available "Tangshan Earthquake" by Feng Xiaogang began shooting at the 2010 Aftershock of a background to the film. Movie tells the story of a mother for her daughter because of the expense of her choice between life and death caused deep trauma, the purpose of this study was to indicate the difference between sex behavior may cause deep psychological trauma. This article uses the collected literature research method, to "Aftershock" movie LiYuanni Stool and post-disaster psychological research scope and use of gender inequality theory, post-disaster trauma psychology to analyze the process of gender inequality in the movie protagonist psychology. Analysis showed that factors of gender inequality is mainly a social problem and a lack of self-consciousness of women. The uneven treatment of choice in pondering Fang Deng and mother for decades. 

  11. Chinese Herbs Containing Aristolochic Acid Associated with Renal Failure and Urothelial Carcinoma: A Review from Epidemiologic Observations to Causal Inference

    Directory of Open Access Journals (Sweden)

    Hsiao-Yu Yang

    2014-01-01

    Full Text Available Herbal remedies containing aristolochic acid (AA have been designated to be a strong carcinogen. This review summarizes major epidemiologic evidence to argue for the causal association between AA exposure and urothelial carcinoma as well as nephropathy. The exposure scenarios include the following: Belgian women taking slimming pills containing single material Guang Fang Ji, consumptions of mixtures of Chinese herbal products in the general population and patients with chronic renal failure in Taiwan, occupational exposure in Chinese herbalists, and food contamination in farming villages in valleys of the Danube River. Such an association is corroborated by detecting specific DNA adducts in the tumor tissue removed from affected patients. Preventive actions of banning such use and education to the healthcare professionals and public are necessary for the safety of herbal remedies.

  12. The status of taxonomy and venom in sea snakes

    DEFF Research Database (Denmark)

    Redsted Rasmussen, Arne; Sanders, Kate L.

    2017-01-01

    The status of taxonomy and venom in sea snakesArne R Rasmussen1, Kate L Sanders21 The Royal Danish Academy of Fine Arts, School of Architecture, Design & Conservation, Copenhagen, Denmark2 School of Earth and Environmental Sciences, University of Adelaide, Adelaide, South Australia 5000, AustraliaSea...... snakes form two aquatic groups of snakes with a flat vertically paddle-form tail (sea kraits and viviparous sea snakes). Sea snakes belong to the same family Elapidae, which also includes the terrestrial mambas, cobra, kraits, taipan and brown snake. All elapids are characterized by the anterior position...... of the poison-fangs on the maxillary bone (proteroglyphous). Globally there are some 70 species of sea snake found in the tropical and subtropical waters of the Indian Ocean and the Pacific Ocean. Most species are found in the Indo-Malayan Archipelago, the China Sea, Indonesia, and the Australian region...

  13. Tears of Venom: Hydrodynamics of Reptilian Envenomation

    Science.gov (United States)

    Young, Bruce A.; Herzog, Florian; Friedel, Paul; Rammensee, Sebastian; Bausch, Andreas; van Hemmen, J. Leo

    2011-05-01

    In the majority of venomous snakes, and in many other reptiles, venom is conveyed from the animal’s gland to the prey’s tissue through an open groove on the surface of the teeth and not through a tubular fang. Here we focus on two key aspects of the grooved delivery system: the hydrodynamics of venom as it interacts with the groove geometry, and the efficiency of the tooth-groove-venom complex as the tooth penetrates the prey’s tissue. We show that the surface tension of the venom is the driving force underlying the envenomation dynamics. In so doing, we explain not only the efficacy of the open groove, but also the prevalence of this mechanism among reptiles.

  14. A new deep-sea species of Barathronus Goode & Bean from Brazil, with notes on Barathronus bicolor Goode & Bean (Ophidiiformes: Aphyonidae

    Directory of Open Access Journals (Sweden)

    Jørgen G. Nielsen

    Full Text Available A new species of Barathronus (Ophidiiformes: Aphyonidae is described from a single, mature male specimen (101 mm SL bottom trawled on the continental slope of Rio Grande do Norte, northeastern Brazil, between 1,964 and 2,045 m depth. The new species is diagnosed among congeners by the following combination of characters: peritoneum transparent, deep-set eyes not visible, eight fangs on vomer, anal fin rays 69, predorsal length 42.0% SL, preanal length 49.5% SL, penis long, slender, and lacking a pair of lobes at its base, and presence of a ventral flexure of the anterior 2-3 vertebrae. Additionally, morphological data of three specimens of Barathronus bicolor collected in Brazilian waters are presented and compared with those from 51 specimens from the western Central Atlantic.

  15. The BEAST II Experiment at Belle II. Characterization of the commissioning detector system for SuperKEKB

    Energy Technology Data Exchange (ETDEWEB)

    Ahlburg, Patrick; Eyring, Andreas; Filimonov, Viacheslav; Krueger, Hans; Mari, Laura; Marinas, Carlos; Pohl, David-Leon; Wermes, Norbert; Dingfelder, Jochen [University of Bonn (Germany)

    2016-07-01

    Before the upgraded vertex detector for the Belle II experiment at the SuperKEKB collider in Japan will be installed, a dedicated detector system for machine commissioning (BEAST II) will be employed. One of its main objectives is to measure and characterize the different background types in order to ensure a safe environment before the installation of the actual silicon detector systems close to the interaction point. FANGS, a detector system at BEAST II, based on ATLAS-IBL front-end electronics and planar silicon sensors is currently being developed for this purpose. The unique feature of this detector system is the high energy resolution achieved by using an external FPGA clock to sample the time-over-threshold signal, while keeping the excellent timing properties. The complete detector system is presented in this talk.

  16. Numerical model to predict microstructure of the heat treated of steel elements

    Directory of Open Access Journals (Sweden)

    T. Domański

    2011-04-01

    Full Text Available In work the presented numerical models of tool steel hardening processes take into account thermal phenomena and phase transformations. Numerical algorithm of thermal phenomena was based on the Finite Elements Methods of the heat transfer equations. In the model of phase transformations, in simulations heating process continuous heating (CHT was applied, whereas in cooling process continuous cooling (CCT of the steel at issue. The phase fraction transformed (austenite during heating and fractions during cooling of ferrite, pearlite or bainite are determined by Johnson-Mehl-Avrami formulas. The nescent fraction of martensite is determined by Koistinen and Marburger formula or modified Koistinen and Marburger formula. In the simulations of hardening was subject the fang lathe of cone (axisymmetrical object made of tool steel.

  17. Numerical analysis of stress fields generated by quenching process

    Directory of Open Access Journals (Sweden)

    A. Bokota

    2011-04-01

    Full Text Available In work the presented numerical models of tool steel hardening processes take into account mechanical phenomena generated by thermalphenomena and phase transformations. In the model of mechanical phenomena, apart from thermal, plastic and structural strain, alsotransformations plasticity was taken into account. The stress and strain fields are obtained using the solution of the Finite Elements Method of the equilibrium equation in rate form. The thermophysical constants occurring in constitutive relation depend on temperature and phase composite. For determination of plastic strain the Huber-Misses condition with isotropic strengthening was applied whereas fordetermination of transformation plasticity a modified Leblond model was used. In order to evaluate the quality and usefulness of thepresented models a numerical analysis of stresses and strains associated hardening process of a fang lathe of cone shaped made of tool steel was carried out.

  18. Characterizing the Stellar Population of NGC 1980

    Energy Technology Data Exchange (ETDEWEB)

    Kounkel, Marina; Hartmann, Lee; Calvet, Nuria [Department of Astronomy, University of Michigan, 1085 S. University Street, Ann Arbor, MI 48109 (United States); Megeath, Tom, E-mail: mkounkel@umich.edu [Ritter Astrophsical Research Center, Department of Physics and Astronomy, University of Toledo, Toledo, OH 43606 (United States)

    2017-07-01

    NGC 1980 is a young cluster that is located about 0.°5 south of the Orion Nebula Cluster (ONC). Recent studies by Bouy et al. and Pillitteri et al. have suggested that NGC 1980 contains an older population of stars compared to a much younger ONC, and that it belongs to a foreground population that may be located in front of the Orion A molecular gas by as much as 40 pc. In this work, we present low-resolution spectra toward 148 young stars found toward the NGC 1980 region. We determine the spectral types of these stars, examine accretion signatures and measure the extinction toward them. We determine that based on these observations, the age of the population of NGC 1980 is indistinguishable from L1641, estimated to be ∼3 Myr, comparable with the study by Fang et al.

  19. Treatment of refractory/relapsed adult acute lymphoblastic leukemia with bortezomib- based chemotherapy

    Directory of Open Access Journals (Sweden)

    Zhao J

    2015-06-01

    Full Text Available Junmei Zhao,* Chao Wang,* Yongping Song, Yuzhang Liu, Baijun FangHenan Key Lab of Experimental Haematology, Henan Institute of Haematology, Henan Tumor Hospital, Zhengzhou University, Zhengzhou, People’s Republic of China  *These authors contributed equally to this work Abstract: Nine pretreated patients aged >19 years with relapsed/refractory acute lymphoblastic leukemia (ALL were treated with a combination of bortezomib plus chemotherapy before allogeneic hematopoietic stem cell transplantation (allo-HSCT. Eight (88.9% patients, including two Philadelphia chromosome-positive ALL patients, achieved a complete remission. Furthermore, the evaluable patients have benefited from allo-HSCT after response to this reinduction treatment. We conclude that bortezomib-based chemotherapy was highly effective for adults with refractory/relapsed ALL before allo-HSCT. Therefore, this regimen deserves a larger series within prospective trials to confirm these results. Keywords: acute lymphoblastic leukemia, refractory, relapsed, bortezomib

  20. ANALYSIS ON THE DYNAMICS OF SPATIAL DISTRIBUTION PATTERN OF MIXED SPIDER POPULATION IN RICE FIELD

    Institute of Scientific and Technical Information of China (English)

    ZhiWang; Zhe-mingYuan; Da-xiangSong; Ming-shengZhu

    2004-01-01

    The results make it clear that there are total 11 families, 29 genera and 43 species of spiders in the rice field of Dong Fang Hong Farm. Among them, there are 8 families, 19 genera and 28 species in the early rice field, and 10 families, 27 genera and 36 species in the late rice field. The spatial distribution pattern of mixed spider populations in rice fields was different during different development stages of rice plant. During the prophase, metaphase and anaphase of early rice plant development, the spatial distribution pattern of mixed spider populations was aggregative, random and aggregative respectively. During the prophase, metaphase and anaphase of late rice plant development, the spatial distribution pattern was uniform, aggregative and uniform respectively.

  1. Electronic transport properties of phenylacetylene molecular junctions

    International Nuclear Information System (INIS)

    Liu Wen; Cheng Jie; Yan Cui-Xia; Li Hai-Hong; Wang Yong-Juan; Liu De-Sheng

    2011-01-01

    Electronic transport properties of a kind of phenylacetylene compound— (4-mercaptophenyl)-phenylacetylene are calculated by the first-principles method in the framework of density functional theory and the nonequilibrium Green's function formalism. The molecular junction shows an obvious rectifying behaviour at a bias voltage larger than 1.0 V. The rectification effect is attributed to the asymmetry of the interface contacts. Moreover, at a bias voltage larger than 2.0 V, which is not referred to in a relevant experiment [Fang L, Park J Y, Ma H, Jen A K Y and Salmeron M 2007 Langmuir 23 11522], we find a negative differential resistance phenomenon. The negative differential resistance effect may originate from the change of the delocalization degree of the molecular orbitals induced by the bias. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

  2. [Ultrafiltration versus intravenous diuretics in decompensated heart failure: a meta-analysis of randomized controlled trials].

    Science.gov (United States)

    Zhao, Yu-liang; Zhang, Ling; Yang, Ying-ying; Tang, Yi; Liu, Fang; Fu, Ping

    2013-08-13

    To explore whether ultrafiltration is superior to intravenous diuretics in ameliorating fluid overload and preserving renal functions in decompensated heart failure patients. By searching in Pubmed, Cochrane Library, Embase, Springer, WanFang, CQVIP, CNKI and CBM database as well as related Chinese journals, qualified randomized controlled trials (RCTs) were included for meta-analysis by Revman 5.0 and STATA 10.0. Six RCTs were included with 241 patients in ultrafiltration group and 240 patients in intravenous diuretics group. Pooled analyses demonstrated ultrafiltration was superior to intravenous diuretics in the aspects of weight loss (WMD = 1.44 kg, 95%CI:0.33-2.55 kg, P = 0.01) and fluid removal (WMD = 1.23 kg, 95%CI:0.63-1.82 kg, P diuretics in mitigating fluid overload. No intergroup difference was observed in renal function preservation, mortality or rehospitalization.

  3. Knowledge Creation in International Joint Ventures in Emerging Economies

    DEFF Research Database (Denmark)

    Nielsen, Ulrik B.

    Entering and developing presence in emerging economies often require foreign firms to set up International Joint Ventures (IJVs) with local partners, especially when the prime motive of the operation is to capture opportunities in the local markets (Mohr & Puck, 2005). IJVs have therefore become...... an important way for firms to enter these markets and a significant force in shaping a firm’s global strategy in expanding international activities abroad. However, research has shown that IJVs in emerging economies are unstable, and firms have experienced that performance of their IJVs in these emerging...... economies often does not meet their expectations (Fang & Zou, 2010). Extant research has shown that, in general, management of IJVs appears to be a difficult issue. 60-70% of all partnerships are not successful (Lambe, Spekman, & Hunt, 2002). Inter-partner learning has been proposed in the literature...

  4. Chinese herbs containing aristolochic acid associated with renal failure and urothelial carcinoma: a review from epidemiologic observations to causal inference.

    Science.gov (United States)

    Yang, Hsiao-Yu; Chen, Pau-Chung; Wang, Jung-Der

    2014-01-01

    Herbal remedies containing aristolochic acid (AA) have been designated to be a strong carcinogen. This review summarizes major epidemiologic evidence to argue for the causal association between AA exposure and urothelial carcinoma as well as nephropathy. The exposure scenarios include the following: Belgian women taking slimming pills containing single material Guang Fang Ji, consumptions of mixtures of Chinese herbal products in the general population and patients with chronic renal failure in Taiwan, occupational exposure in Chinese herbalists, and food contamination in farming villages in valleys of the Danube River. Such an association is corroborated by detecting specific DNA adducts in the tumor tissue removed from affected patients. Preventive actions of banning such use and education to the healthcare professionals and public are necessary for the safety of herbal remedies.

  5. The influence of coal bottom ash and tincal (boron mineral) additions on the physical and microstructures of ceramic bodies

    Energy Technology Data Exchange (ETDEWEB)

    Bayca, S.U.; Batar, T.; Sayin, E.; Solak, O.; Kahraman, B. [Celal Bayar University, Manisa (Turkey). Soma Vocational School

    2008-07-01

    In this paper, the influence of coal bottom ash and tincal additions on the physical properties and microstructures of the standard wall tile body composition was investigated. Water absorption, fang strength, dry and fired shrinkage tests of the incorporated ceramic bodies and reference body were done. Microstructures of sintered tiles were analyzed using a scanning electron microscope (SEM). The results show that tincal additions to the ceramic body improved the physical properties of the tiles. As a result, tincal can be used as a flux material in the ceramic bodies due to its favorable effects on the water absorption and fired strength. The results revealed that bottom ash can be used in the ceramic tile body composition. When bottom ash was used in the ceramic industry, environmental hazards of bottom ash are inhibited. Furthermore, bottom ash is transformed to an economic product.

  6. Type I enteropathy-associated T-cell lymphoma in the colon of a 29-year-old patient and a brief literature review

    Directory of Open Access Journals (Sweden)

    Zhang JC

    2016-02-01

    Full Text Available Jiu-Cong Zhang, Yong Wang, Xiu-Feng Wang, Fang-Xin Zhang Department of Gastroenterology, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, People’s Republic of China Abstract: Enteropathy-associated T-cell lymphoma (EATL is a rare gastrointestinal non-Hodgkin’s lymphoma, originating from intraepithelial T-lymphocyte, which is specifically associated with celiac disease. EATL most commonly presents in the sixth and seventh decades of life. We report a unique case of type I EATL in the colon with liver metastasis, which was presented with nonspecific radiological findings and at a very young age (29 years old compared with previously published data. We suggest that EATL should be regarded as part of differential diagnosis in any patient presenting with abdominal pain, diarrhea, weight loss, and malabsorption because delay in treatment can result in an irreversible clinical outcome. Keywords: enteropathy-associated T-cell lymphoma, colon, ulcer, liver metastasis

  7. Optimization of scanning strategy of digital Shack-Hartmann wavefront sensing.

    Science.gov (United States)

    Guo, Wenjiang; Zhao, Liping; Li, Xiang; Chen, I-Ming

    2012-01-01

    In the traditional Shack-Hartmann wavefront sensing (SHWS) system, a lenslet array with a bigger configuration is desired to achieve a higher lateral resolution. However, practical implementation limits the configuration and this parameter is contradicted with the measurement range. We have proposed a digital scanning technique by making use of the high flexibility of a spatial light modulator to sample the reflected wavefront [X. Li, L. P. Zhao, Z. P. Fang, and C. S. Tan, "Improve lateral resolution in wavefront sensing with digital scanning technique," in Asia-Pacific Conference of Transducers and Micro-Nano Technology (2006)]. The lenslet array pattern is programmed to laterally scan the whole aperture. In this paper, the methodology to optimize the scanning step for the purpose of form measurement is proposed. The correctness and effectiveness are demonstrated in numerical simulation and experimental investigation. © 2012 Optical Society of America

  8. Impacted science: impact is not importance.

    Science.gov (United States)

    Casadevall, Arturo; Fang, Ferric C

    2015-10-13

    The journal impact factor (IF) exerts a tremendous influence on the conduct of scientists. The obsession with IF has been compared to a medical condition, sometimes referred to as "IF mania" or "impactitis." Here, we analyze the difference between impact and importance, using examples from the history of science to show that these are not equivalent. If impact does not necessarily equal importance, but scientists are focused on high-impact work, there is a danger that misuse of the IF may adversely affect scientific progress. We suggest five measures to fight this malady: (i) diversify journal club selections, (ii) do not judge science on the publication venue, (iii) reduce the reliance on journal citation metrics for employment and advancement, (iv) discuss the misuse of the IF in ethics courses, and (v) cite the most appropriate sources. If IF mania is indeed a medical condition, the most appropriate course of action may be disimpaction. Copyright © 2015 Casadevall and Fang.

  9. Prevalence of epilepsy in China between 1990 and 2015

    DEFF Research Database (Denmark)

    Song, Peige; Liu, Yezhou; Yu, Xinwei

    2017-01-01

    in mainland China from 1990 to 2015and explores the variations of burden by age and gender. Methods: We conducted a systematic review of the peer–reviewed literature from 1990 to 2015 using Chinese and English academic databases (CNKI, WanFang, VIP and PubMed) to identify population–based prospective studies...... = 1.31–3.02) in 1990 to7.15‰ (95% CI = 3.98–12.82) in 2015. The rates of increase were similar across the whole age spectrum, fluctuating around 250%. Between 1990 and 2015, the total number of people with LTE inmainland China increased by 328%, from 2.30 million (95%CI = 1.51–3.49) in 1990 to 9...

  10. Influence of sewage sludge addition from water treatment plants on the concrete setting and hydration in Portland cement pastes

    OpenAIRE

    Seguí Consul, Sergi

    2007-01-01

    La següent tesina estudia l'efecte de l'addicció des llots secs procedents de les depuradores d'aigües residuals de Vic, Rubí i Montornès del Vallès sobre les reaccions de presa i enduriment de diferents pastes de ciment Pòrtland a curt termini. Aquest treball s'emmarca dins d'un estudi consistent en l'addicció de fangs estabilitzants per a la fabricació de morters de ciment Pòrtland, amb la finalitat de trobar alternatives adapatades a les actuals polítiques ambientals. L'estudi s'inicia l'a...

  11. [Design and establishment of modern literature database about acupuncture Deqi].

    Science.gov (United States)

    Guo, Zheng-rong; Qian, Gui-feng; Pan, Qiu-yin; Wang, Yang; Xin, Si-yuan; Li, Jing; Hao, Jie; Hu, Ni-juan; Zhu, Jiang; Ma, Liang-xiao

    2015-02-01

    A search on acupuncture Deqi was conducted using four Chinese-language biomedical databases (CNKI, Wan-Fang, VIP and CBM) and PubMed database and using keywords "Deqi" or "needle sensation" "needling feeling" "needle feel" "obtaining qi", etc. Then, a "Modern Literature Database for Acupuncture Deqi" was established by employing Microsoft SQL Server 2005 Express Edition, introducing the contents, data types, information structure and logic constraint of the system table fields. From this Database, detailed inquiries about general information of clinical trials, acupuncturists' experience, ancient medical works, comprehensive literature, etc. can be obtained. The present databank lays a foundation for subsequent evaluation of literature quality about Deqi and data mining of undetected Deqi knowledge.

  12. Fracture mechanics of piezoelectric and ferroelectric solids

    CERN Document Server

    Fang, Daining

    2013-01-01

    Fracture Mechanics of Piezoelectric and Ferroelectric Solids presents a systematic and comprehensive coverage of the fracture mechanics of piezoelectric/ferroelectric materials, which includes the theoretical analysis, numerical computations and experimental observations. The main emphasis is placed on the mechanics description of various crack problems such static, dynamic and interface fractures as well as the physical explanations for the mechanism of electrically induced fracture. The book is intended for postgraduate students, researchers and engineers in the fields of solid mechanics, applied physics, material science and mechanical engineering. Dr. Daining Fang is a professor at the School of Aerospace, Tsinghua University, China; Dr. Jinxi Liu is a professor at the Department of Engineering Mechanics, Shijiazhuang Railway Institute, China.

  13. The Association Between Maternal Subclinical Hypothyroidism and Growth, Development, and Childhood Intelligence: A Meta-analysis

    Science.gov (United States)

    Liu, Yahong; Chen, Hui; Jing, Chen; Li, FuPin

    2018-06-01

    To explore the association between maternal subclinical hypothyroidism (SCH) in pregnancy and the somatic and intellectual development of their offspring. Using RevMan 5.3 software, a meta-analysis of cohort studies published from inception to May 2017, focusing on the association between maternal SCH in pregnancy and childhood growth, development and intelligence, was performed. Sources included the Cochrane Library, Pub-Med, Web of Science, China National Knowledge Infrastructure and Wan Fang Data. Analysis of a total of 15 cohort studies involving 1.896 pregnant women with SCH revealed that SCH in pregnancy was significantly associated with the intelligence (p=0.0007) and motor development (pdevelopment, low birth weight, premature delivery, fetal distress and fetal growth restriction.

  14. Didaktik, leg og læring

    DEFF Research Database (Denmark)

    Broström, Stig

    2017-01-01

    målrettet og bevidst kan konstruere og planlægge pædagogiske forløb. Og som en tredje dimension selv at kunne udvikle didaktiske teori og formidle denne til forældre, kollegaer og det pædagogiske felt. Begrebet didaktik og didaktisk virksomhed har traditionelt været lærernes og skolens domæne. Således er...... dynamisk form for undervisning, nemlig at (under)vise hen til det betydningsfulde. Det pædagogiske indhold er en afgørende del af didaktikken. Pædagogen må tænker over, hvad der kan være vigtigt at bringe ind i børns liv, samt at planlægge hvordan man generelt kan fange det betydningsfulde, dét der skal...

  15. A Semantically Enabled Portal for Facilitating the Public Service Provision

    Science.gov (United States)

    Loutas, Nikolaos; Giantsiou, Lemonia; Peristeras, Vassilios; Tarabanis, Konstantinos

    During the past years, governments have made significant efforts to improve both their internal processes and the services that they provide to citizens and businesses. These led to several successful e-Government applications (e.g., see www.epractice.eu). One of the most popular tools that was used by governments in order to modernize their services and make them accessible is e-Government portals, e.g., (Drigas et al. 2005), (Fang 2002). The main goals of such portals are: To make available complete, easy to understand, and structured information about public services and public administration's modus operandi, which will assist citizens during the service provision process. To facilitate the electronic execution of public services. Nevertheless, most of such efforts did not succeed. Gartner argues that most e-Government strategies have not achieved their objectives and have failed to trigger sustainable government transformation to greater efficiency and citizen-centricity (DiMaio 2007).

  16. Probiotics Supplementation Therapy for Pathological Neonatal Jaundice: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Chen, Zhe; Zhang, Lingli; Zeng, Linan; Yang, Xiaoyan; Jiang, Lucan; Gui, Ge; Zhang, Zuojie

    2017-01-01

    Background: Neonatal jaundice is a relatively prevalent disease and affects approximately 2.4-15% newborns. Probiotics supplementation therapy could assist to improve the recovery of neonatal jaundice, through enhancing immunity mainly by regulating bacterial colonies. However, there is limited evidence regarding the effect of probiotics on bilirubin level in neonates. Therefore, this study aims at systematically evaluating the efficacy and safety of probiotics supplement therapy for pathological neonatal jaundice. Methods: Databases including PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wan Fang Database (Wan Fang), Chinese Biomedical Literature Database (CBM), VIP Database for Chinese Technical Periodicals (VIP) were searched and the deadline is December 2016. Randomized controlled trials (RCTs) of probiotics supplementation for pathological neonatal jaundice in publications were extracted by two reviewers. The cochrane tool was applied to assessing the risk of bias of the trials. The extracted information of RCTs should include efficacy rate, serum total bilirubin level, time of jaundice fading, duration of phototherapy, duration of hospitalization, adverse reactions. The main outcomes of the trials were analyzed by Review Manager 5.3 software. The relative risks (RR) or mean difference (MD) with a 95% confidence interval (CI) was used to measure the effect. Results: 13 RCTs involving 1067 neonatal with jaundice were included in the meta-analysis. Probiotics supplementation treatment showed efficacy [RR: 1.19, 95% CI (1.12, 1.26), P jaundice. It not only decreased the total serum bilirubin level after 3day [MD: -18.05, 95% CI (-25.51, -10.58), P jaundice fading [MD: -1.91, 95% CI (-2.06, -1.75), P probiotics supplementation therapy is an effective and safe treatment for pathological neonatal jaundice.

  17. What killed Karl Patterson Schmidt? Combined venom gland transcriptomic, venomic and antivenomic analysis of the South African green tree snake (the boomslang), Dispholidus typus.

    Science.gov (United States)

    Pla, Davinia; Sanz, Libia; Whiteley, Gareth; Wagstaff, Simon C; Harrison, Robert A; Casewell, Nicholas R; Calvete, Juan J

    2017-04-01

    Non-front-fanged colubroid snakes comprise about two-thirds of extant ophidian species. The medical significance of the majority of these snakes is unknown, but at least five species have caused life-threatening or fatal human envenomings. However, the venoms of only a small number of species have been explored. A combined venomic and venom gland transcriptomic approach was employed to characterise of venom of Dispholidus typus (boomslang), the snake that caused the tragic death of Professor Karl Patterson Schmidt. The ability of CroFab™ antivenom to immunocapture boomslang venom proteins was investigated using antivenomics. Transcriptomic-assisted proteomic analysis identified venom proteins belonging to seven protein families: three-finger toxin (3FTx); phospholipase A 2 (PLA 2 ); cysteine-rich secretory proteins (CRISP); snake venom (SV) serine proteinase (SP); C-type lectin-like (CTL); SV metalloproteinases (SVMPs); and disintegrin-like/cysteine-rich (DC) proteolytic fragments. CroFab™ antivenom efficiently immunodepleted some boomslang SVMPs. The present work is the first to address the overall proteomic profile of D. typus venom. This study allowed us to correlate the toxin composition with the toxic activities of the venom. The antivenomic analysis suggested that the antivenom available at the time of the unfortunate accident could have exhibited at least some immunoreactivity against the boomslang SVMPs responsible for the disseminated intravascular coagulation syndrome that caused K.P. Schmidt's fatal outcome. This study may stimulate further research on other non-front-fanged colubroid snake venoms capable of causing life-threatening envenomings to humans, which in turn should contribute to prevent fatal human accidents, such as that unfortunately suffered by K.P. Schmidt. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  18. Development of interactive graphic user interfaces for modeling reaction-based biogeochemical processes in batch systems with BIOGEOCHEM

    Science.gov (United States)

    Chang, C.; Li, M.; Yeh, G.

    2010-12-01

    The BIOGEOCHEM numerical model (Yeh and Fang, 2002; Fang et al., 2003) was developed with FORTRAN for simulating reaction-based geochemical and biochemical processes with mixed equilibrium and kinetic reactions in batch systems. A complete suite of reactions including aqueous complexation, adsorption/desorption, ion-exchange, redox, precipitation/dissolution, acid-base reactions, and microbial mediated reactions were embodied in this unique modeling tool. Any reaction can be treated as fast/equilibrium or slow/kinetic reaction. An equilibrium reaction is modeled with an implicit finite rate governed by a mass action equilibrium equation or by a user-specified algebraic equation. A kinetic reaction is modeled with an explicit finite rate with an elementary rate, microbial mediated enzymatic kinetics, or a user-specified rate equation. None of the existing models has encompassed this wide array of scopes. To ease the input/output learning curve using the unique feature of BIOGEOCHEM, an interactive graphic user interface was developed with the Microsoft Visual Studio and .Net tools. Several user-friendly features, such as pop-up help windows, typo warning messages, and on-screen input hints, were implemented, which are robust. All input data can be real-time viewed and automated to conform with the input file format of BIOGEOCHEM. A post-processor for graphic visualizations of simulated results was also embedded for immediate demonstrations. By following data input windows step by step, errorless BIOGEOCHEM input files can be created even if users have little prior experiences in FORTRAN. With this user-friendly interface, the time effort to conduct simulations with BIOGEOCHEM can be greatly reduced.

  19. Individual taper models for natural cedar and Taurus fir mixed stands of Bucak Region, Turkey

    Directory of Open Access Journals (Sweden)

    Ramazan Özçelik

    2017-11-01

    Full Text Available In this study, we assessed the performance of different types of taper equations for predicting tree diameters at specific heights and total stem volumes for mixed stands of Taurus cedar (Cedrus libani A. Rich. and Taurus fir (Abies cilicica Carr.. We used data from mixed stands containing a total of 131 cedar and 124 Taurus fir trees. We evaluated six commonly used and well-known forestry taper functions developed by a variety of researchers (Biging (1984, Zakrzewski (1999, Muhairwe (1999, Fang et al. (2000, Kozak (2004, and Sharma and Zhang (2004. To address problems related to autocorrelation and multicollinearity in the hierarchical data associated with the construction of taper models, we used appropriate statistical procedures for the model fitting. We compared model performances based on the analysis of three goodness-of-fit statistics and found the compatible segmented model of Fang et al. (2000 to be superior in describing the stem profile and stem volume of both tree species in mixed stands. The equation used by Zakrzewski (1999 exhibited the poorest fitting results of the three taper equations. In general, we found segmented taper equations to provide more accurate predictions than variable-form models for both tree species. Results from the non-linear extra sum of squares method indicate that stem tapers differ among tree species in mixed stands. Therefore, a different taper function should be used for each tree species in mixed stands in the Bucak district. Using individual-specific taper equations yields more robust estimations and, therefore, will enhance the prediction accuracy of diameters at different heights and volumes in mixed stands.

  20. Follow-up of pregnant woman 16 years after exposure in Xinzhou radiation accident

    International Nuclear Information System (INIS)

    Zhang Zhaohui; Zhang Shulan; Jia Tingzhen; Liu Qingjie; Liang Li; Su Xu; Ma Liwen; Qin Bin; Chen Sen; Wang Wenxue

    2010-01-01

    Objective: To investigate the late effect of radiation on child-bearing women, through observing 'Fang', a 19-week-pregnant woman at age of 23, who was exposed to 60 Co radiation in Shanxi Xinzhou radiation accident in November, 1992 and diagnosed as moderate bone marrow type acute radiation sickness and recovered after 16 year of follow-up treatment. Methods: Clinical data including medical history, physical examination, laboratory data, imaging findings and consulting relevant departments were reviewed. Results: The followed-up woman 'Fang' often felt weak and caught cold after recovery. When she was 32 years old (9 years after radiation), her hair turned grey, but without hair loss. Her menstrual quantitiy was lessened since 31 years old (8 years after radiation). She was remarried and pregnant twice in the same year. At the first time she underwent artificial abortion and the second child suffered from intrauterine death after 6 months of pregnancy. The physical examination found bilateral degree I thyroid enlargement and sparse armpit hair. The laboratory test showed the increased levels of triiodothyronine, thyroxine and anti-thyroid peroxidase antibody (TMAb) and the decreased thyroid stimulating hormone (TSH). Unstable chromosome aberrations were totally lost and stable aberrations in chromosomes were detected by fluorescence in situ hybridization (FISH). The dose estimated with the residue chromosome aberration was 0.76 Gy. Other laboratory results were normal. Ultrasonic test showed diffuse lesion in bilateral thyroid and multiple cystic nodules in right lobe of thyroid, which was considered to be nodular goiter. The examination of bone mineral density (BMD) showed osteoporosis from the second to the fourth lumber vertebra. There were no diseases associated with radiation based on the consultation from related departments. Conclusions: Intrauterine death after 6 months of pregnancy might be associated with the previous exposure. There is no evidence of

  1. Role of a Transcriptional Regulator in Programmed Cell Death and Plant Development

    Energy Technology Data Exchange (ETDEWEB)

    Julie M. Stone

    2008-09-13

    The long-term goal of this research is to understand the role(s) and molecular mechanisms of programmed cell death (PCD) in the controlling plant growth, development and responses to biotic and abiotic stress. We developed a genetic selection scheme to identify A. thaliana FB1-resistant (fbr) mutants as a way to find genes involved in PCD (Stone et al., 2000; Stone et al., 2005; Khan and Stone, 2008). The disrupted gene in fbr6 (AtSPL14) responsible for the FB1-insensitivity and plant architecture phenotypes encodes a plant-specific SBP DNA-binding domain transcriptional regulator (Stone et al., 2005; Liang et al., 2008). This research plan is designed to fill gaps in the knowledge about the role of SPL14 in plant growth and development. The work is being guided by three objectives aimed at determining the pathways in which SPL14 functions to modulate PCD and/or plant development: (1) determine how SPL14 functions in plant development, (2) identify target genes that are directly regulated by SPL14, and (3) identify SPL14 modifications and interacting proteins. We made significant progress during the funding period. Briefly, some major accomplishments are highlighted below: (1) To identify potential AtSPL14 target genes, we identified a consensus DNA binding site for the AtSPL14 SBP DNA-binding domain using systematic evolution of ligands by exponential selection (SELEX) and site-directed mutagenesis (Liang et al., 2008). This consensus binding site was used to analyze Affymetrix microarray gene expression data obtained from wild-type and fbr6 mutant plants to find possible AtSPL14-regulated genes. These candidate AtSPL14-regulated genes are providing new information on the molecular mechanisms linking plant PCD and plant development through modulation of the 26S proteasome. (2) Transgenic plants expressing epitope-tagged versions of AtSPL14 are being used to confirm the AtSPL14 targets (by ChIP-PCR) and further dissect the molecular interactions (Nazarenus, Liang

  2. Silicate melt metasomatism in the lithospheric mantle beneath SW Poland

    Science.gov (United States)

    Puziewicz, Jacek; Matusiak-Małek, Magdalena; Ntaflos, Theodoros; Grégoire, Michel; Kukuła, Anna

    2014-05-01

    The xenoliths of peridotites representing the subcontinental lithospheric mantle (SCLM) beneath SW Poland and adjacent parts of Germany occur in the Cenozoic alkaline volcanic rocks. Our study is based on detailed characterization of xenoliths occurring in 7 locations (Steinberg in Upper Lusatia, Księginki, Pilchowice, Krzeniów, Wilcza Góra, Winna Góra and Lutynia in Lower Silesia). One of the two major lithologies occurring in the xenoliths, which we call the "B" lithology, comprises peridotites (typically harzburgites) with olivine containing from 90.5 to 84.0 mole % of forsterite. The harzburgites contain no clinopyroxene or are poor in that mineral (eg. in Krzeniów the group "B" harzburgites contain pfu in ortho-, and pfu in clinopyroxene). The exception are xenoliths from Księginki, which contain pyroxenes characterised by negative correlation between mg# and Al. The REE patterns of both ortho- and clinopyroxene in the group "B" peridotites suggest equilibration with silicate melt. The rocks of "B" lithology were formed due to alkaline silicate melt percolation in the depleted peridotitic protolith. The basaltic melts formed at high pressure are usually undersaturated in both ortho- and clinopyroxene at lower pressures (Kelemen et al. 1992). Because of cooling and dissolution of ortho- and clinopyroxene the melts change their composition and become saturated in one or both of those phases. Experimental results (e.g. Tursack & Liang 2012 and references therein) show that the same refers to alkaline basaltic silicate melts and that its reactive percolation in the peridotitic host leads to decrease of Mg/(Mg+Fe) ratios of olivine and pyroxenes. Thus, the variation of relative volumes of olivine and orthopyroxene as well as the decrease of mg# of rock-forming silicates is well explained by reactive melt percolation in the peridotitic protolith consisting of high mg# olivine and pyroxenes (in the area studied by us that protolith was characterised by olivine

  3. PREFACE: XXVIII International Conference on Photonic, Electronic and Atomic Collisions (ICPEAC 2013)

    Science.gov (United States)

    Xiao, Guoqing; Cai, Xiaohong; Ding, Dajun; Ma, Xinwen; Zhao, Yongtao

    2014-04-01

    express its great appreciation to National Natural Science Foundation of China (NSFC), Chinese Academy of Sciences (CAS), International Union of Pure and Applied Physics (IUPAP), IMP, and IMP-YIPA for financial support, to Fangfang Ruan, Qiang Liang, Dacheng Zhang, Shukai Tian, Yuyu Wang, Wenping Zhu, Wei Liang, Mingwu Zhang, Haibo Yuan, Shan Sha, Jieru Ren, Jie Yang and Zhenhai Chen for their contributions to the organization, and to the volunteer group from Lanzhou University, the High School Attached Northwest Normal University and IMP for their excellent volunteer work. The Local Organizing Committee would like to thank all of the participants and the authors of the proceedings for their supports and contributions to the conference. Guoqing Xiao Director of Institute of Modern Physics, Chinese Academy of Sciences

  4. Diagnostic and prognostic value of carcinoembryonic antigen in pancreatic cancer: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Meng Q

    2017-09-01

    Full Text Available Qingcai Meng,1–3,* Si Shi,1–3,* Chen Liang,1–3,* Dingkong Liang,1–3 Wenyan Xu,1–3 Shunrong Ji,1–3 Bo Zhang,1–3 Quanxing Ni,1–3 Jin Xu,1–3 Xianjun Yu1–3 1Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, 2Department of Oncology, Shanghai Medical College, 3Pancreatic Cancer Institute, Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: Carcinoembryonic antigen (CEA is one of the most widely used tumor markers and is increased in 30%–60% of patients with pancreatic cancer. Although carbohydrate antigen 19-9 (CA19-9 is the most important serum biomarker in pancreatic cancer, the diagnostic and prognostic value of CEA is gradually being recognized.Materials and methods: The MEDLINE, EMBASE, and Web of Science databases were searched for related literature published until January 2017. Diagnostic accuracy variables were pooled using the Meta-Disc software. The pooled hazard ratios (HRs for prognostic data were calculated and analyzed using Stata software.Results: A total of 3,650 participants enrolled in 19 studies met our inclusion criteria. The pooled sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of a CEA-based panel were 0.45 (95% confidence interval [CI], 0.41–0.50, 0.89 (95% CI, 0.86–0.91, 5.39 (95% CI, 3.16–9.18, and 0.55 (95% CI, 0.41–0.72, respectively. The area under the curve (AUC, 0.90 and Q-value (0.84 of the CEA-based panel indicated a significantly higher diagnostic accuracy compared with CEA or CA19-9 alone. Moreover, there was also a significant association between high levels of CEA and worse overall survival (HR, 1.43; 95% CI, 1.31–1.56.Conclusion: Our meta-analysis indicated that elevated serum CEA level, as a vital supplementary to CA19-9, can play an important role in the clinical diagnosis of pancreatic cancer patients and predict poor prognosis. Keywords: carcinoembryonic

  5. Detection of Heart Sounds in Children with and without Pulmonary Arterial Hypertension--Daubechies Wavelets Approach.

    Directory of Open Access Journals (Sweden)

    Mohamed Elgendi

    Full Text Available Automatic detection of the 1st (S1 and 2nd (S2 heart sounds is difficult, and existing algorithms are imprecise. We sought to develop a wavelet-based algorithm for the detection of S1 and S2 in children with and without pulmonary arterial hypertension (PAH.Heart sounds were recorded at the second left intercostal space and the cardiac apex with a digital stethoscope simultaneously with pulmonary arterial pressure (PAP. We developed a Daubechies wavelet algorithm for the automatic detection of S1 and S2 using the wavelet coefficient 'D6' based on power spectral analysis. We compared our algorithm with four other Daubechies wavelet-based algorithms published by Liang, Kumar, Wang, and Zhong. We annotated S1 and S2 from an audiovisual examination of the phonocardiographic tracing by two trained cardiologists and the observation that in all subjects systole was shorter than diastole.We studied 22 subjects (9 males and 13 females, median age 6 years, range 0.25-19. Eleven subjects had a mean PAP < 25 mmHg. Eleven subjects had PAH with a mean PAP ≥ 25 mmHg. All subjects had a pulmonary artery wedge pressure ≤ 15 mmHg. The sensitivity (SE and positive predictivity (+P of our algorithm were 70% and 68%, respectively. In comparison, the SE and +P of Liang were 59% and 42%, Kumar 19% and 12%, Wang 50% and 45%, and Zhong 43% and 53%, respectively. Our algorithm demonstrated robustness and outperformed the other methods up to a signal-to-noise ratio (SNR of 10 dB. For all algorithms, detection errors arose from low-amplitude peaks, fast heart rates, low signal-to-noise ratio, and fixed thresholds.Our algorithm for the detection of S1 and S2 improves the performance of existing Daubechies-based algorithms and justifies the use of the wavelet coefficient 'D6' through power spectral analysis. Also, the robustness despite ambient noise may improve real world clinical performance.

  6. Bortezomib-based vs non-bortezomib-based post-transplantation treatment in multiple myeloma patients: a systematic review and meta-analysis of Phase III randomized controlled trials

    Directory of Open Access Journals (Sweden)

    Liu XP

    2015-06-01

    Full Text Available Xiaoping Liu,1 Colin K He,2 Xiangyu Meng,1 Li He,1 Kaili Li,1 Qing Liang,1 Liang Shao,1 Shangqin Liu1 1Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Orient Health Care, NYC, USA Objective: To evaluate the efficacy and safety of bortezomib-based vs non-bortezomib-based post-transplantation therapy in patients with multiple myeloma.Methods: Data of relevant randomized controlled trials assessing the effect of bortezomib as post-transplantation consolidation or maintenance therapy was obtained through a comprehensive search. The outcome measures included response rate, progression-free survival, overall survival, and adverse events (AEs. The hazard ratio (HR, Cochran-Mantel-Haenszel odds ratio (OR, and 95% confidence interval (95% CI were applied to evaluate the effect of bortezomib in relation to the end points such as progression-free survival, overall survival, response rate, and AEs.Results: Three randomized controlled trials comprising 1,518 participants were included in this study. Pooled ORs for the rates of overall response, and complete response and near complete response, were 1.85 and 1.75, respectively. Pooled HR for progression-free survival favored bortezomib-based therapy over non-bortezomib-based therapy (0.73, 95% CI: 0.67–0.81, while no statistically significant difference could be found between the two groups regarding the pooled HR for 3-year overall survival. Moreover, incidence rates of overall adverse events and grade 3 and 4 peripheral neuropathy were similar in the bortezomib-based groups and the non-bortezomib-based groups (P=0.12 and P=0.41, respectively. The corresponding cumulative meta-analyses of the rates of overall response rate, complete response and near complete response, and grades 3 and 4 peripheral neuropathy supported the superiority of bortezomib-based maintenance therapy over consolidation therapy.Conclusion: Bortezomib-based therapy after

  7. A Crystallization-Temperature Profile Through Paleo-Oceanic Crust (Wadi Gideah Transect, Oman Ophiolite): Application of the REE-in-Plagioclase-Clinopyroxene Partitioning Thermometer

    Science.gov (United States)

    Mueller, S.; Hasenclever, J.; Garbe-Schönberg, D.; Koepke, J.; Hoernle, K.

    2017-12-01

    The accretion mechanisms forming oceanic crust at fast spreading ridges are still under controversial discussion. Thermal, petrological, and geochemical observations predict different end-member models, i.e., the gabbro glacier and the sheeted sill model. They all bear implications for heat transport, temperature distribution, mode of crystallization and hydrothermal heat removal over crustal depth. In a typical MOR setting, temperature is the key factor driving partitioning of incompatible elements during crystallization. LA-ICP-MS data for co-genetic plagioclase and clinopyroxene in gabbros along a transect through the plutonic section of paleo-oceanic crust (Wadi Gideah Transect, Oman ophiolite) reveal that REE partitioning coefficients are relatively constant in the layered gabbro section but increase for the overlying foliated gabbros, with an enhanced offset towards HREEs. Along with a systematic enrichment of REE's with crustal height, these trends are consistent with a system dominated by in-situ crystallization for the lower gabbros and a change in crystallization mode for the upper gabbros. Sun and Liang (2017) used experimental REE partitioning data for calibrating a new REE-in-plagioclase-clinopyroxene thermometer that we used here for establishing the first crystallization-temperature depth profile through oceanic crust that facilitates a direct comparison with thermal models of crustal accretion. Our results indicate crystallization temperatures of about 1220±8°C for the layered gabbros and lower temperatures of 1175±8°C for the foliated gabbros and a thermal minimum above the layered-to-foliated gabbro transition. Our findings are consistent with a hybrid accretion model for the oceanic crust. The thermal minimum is assumed to represent a zone where the descending crystal mushes originating from the axial melt lens meet with mushes that have crystallized in situ. These results can be used to verify and test thermal models (e.g., Maclennan et al

  8. Localized multi-scale energy and vorticity analysis. II. Finite-amplitude instability theory and validation

    Science.gov (United States)

    San Liang, X.; Robinson, Allan R.

    2007-12-01

    A novel localized finite-amplitude hydrodynamic stability analysis is established in a unified treatment for the study of real oceanic and atmospheric processes, which are in general highly nonlinear, and intermittent in space and time. We first re-state the classical definition using the multi-scale energy and vorticity analysis (MS-EVA) developed in Liang and Robinson [Liang, X.S., Robinson, A.R., 2005. Localized multiscale energy and vorticity analysis. I. Fundamentals. Dyn. Atmos. Oceans 38, 195-230], and then manipulate certain global operators to achieve the temporal and spatial localization. The key of the spatial localization is transfer-transport separation, which is made precise with the concept of perfect transfer, while relaxation of marginalization leads to the localization of time. In doing so the information of transfer lost in the averages is retrieved and an easy-to-use instability metric is obtained. The resulting metric is field-like (Eulerian), conceptually generalizing the classical formalism, a bulk notion over the whole system. In this framework, an instability has a structure, which is of particular use for open flow processes. We check the structure of baroclinic instability with the benchmark Eady model solution, and the Iceland-Faeroe Frontal (IFF) intrusion, a highly localized and nonlinear process occurring frequently in the region between Iceland and Faeroe Islands. A clear isolated baroclinic instability is identified around the intrusion, which is further found to be characterized by the transition from a spatially growing mode to a temporally growing mode. We also check the consistency of the MS-EVA dynamics with the barotropic Kuo model. An observation is that a local perturbation burst does not necessarily imply an instability: the perturbation energy could be transported from other processes occurring elsewhere. We find that our analysis yields a Kuo theorem-consistent mean-eddy interaction, which is not seen in a conventional

  9. Investigation of the Swirl Effect on Engine Using Designed Swirl Adapter

    Directory of Open Access Journals (Sweden)

    Mohiuddin AKM

    2011-12-01

    Full Text Available Swirl is the rotational flow of charge within the cylinder about its axis. The engine used in this investigation is a basic Double Overhead Camshaft (DOHC which has a capacity of 1597 cc and installed with a total of 16 valves developed by Malaysian car manufacturer PROTON. The swirl adapter is placed inside the intake port of the Engine. The Adapter angle is set to 30o to force the charge to bounce off the wall of the port to create swirl. The objective of this paper is to find the effect of swirl on the engine and to compare it with the normal turbulence mixing process. The swirl effect analysis is done by using the GT-SUITE which has a standard swirl flow embedded in the software. The effect is simulated on the GT-SUITE and it is found that the swirl affects the engine in reducing the fuel consumption and increasing the volumetric efficiency. The experimental result shows that the effect of swirl increases the power as well as torque in the idle and cruising speed conditions in comparison with normal turbulence. But it decreases rapidly in the acceleration speed. This happens due to the inability of the swirl adapter to generate swirl at higher wind flow velocity during the higher throttle opening condition.ABSTRAK: Pusar merupakan aliran putaran cas melingkungi silinder pada paksinya. Enjin yang digunakan untuk penyelidikan ini merupakan Enjin Aci Sesondol Stas Kembar (Double Overhead Camshaft (DOHC asas, yang mempunyai kapasiti 1597 cc. Ia dipasangkan dengan 16 injap yang dibangunkan oleh pembuat kereta Malaysia, PROTON. Penyesuai pusar diletakkan di dalam masukan liang enjin. Sudut penyesuai di tetapkan pada 30o untuk memaksa cas supaya melantun kepada dinding liang agar membentuk pusaran. Tujuan tesis ini ditulis adalah untuk mendapatkan kesan pusar ke atas enjin dan membandingkannya dengan proses percampuran gelora normal. Analisis kesan pusaran dilakukan dengan menggunakan GT-SUITE yang mempunyai aliran pusar yang telah dipiawaikan di

  10. The outcomes of intra-aortic balloon pump usage in patients with acute myocardial infarction: a comprehensive meta-analysis of 33 clinical trials and 18,889 patients

    Directory of Open Access Journals (Sweden)

    Fan ZG

    2016-03-01

    Full Text Available Zhong-Guo Fan,1,* Xiao-Fei Gao,1,2,* Li-Wen Chen,1 Xiao-Bo Li,1,2 Ming-Xue Shao,1,2 Qian Ji,1 Hao Zhu,1 Yi-Zhi Ren,1 Shao-Liang Chen,1,2 Nai-Liang Tian1,2 1Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 2Department of Cardiology, Nanjing Heart Center, Nanjing, People’s Republic of China *These authors contributed equally to this work Background: The effects of intra-aortic balloon pump (IABP usage in patients with acute myocardial infarction remain controversial. This study sought to evaluate the outcomes of IABP usage in these patients.Methods: Medline, EMBASE, and other internet sources were searched for relevant clinical trials. The primary efficacy endpoints (in-hospital, midterm, and long-term mortality and secondary endpoints (reinfarction, recurrent ischemia, and new heart failure in the hospital as well as safety endpoints (severe bleeding requiring blood transfusion and stroke in-hospital were subsequently analyzed.Results: Thirty-three clinical trials involving 18,889 patients were identified. The risk of long-term mortality in patients suffering from acute myocardial infarction was significantly decreased following IABP use (odds ratio [OR] 0.66, 95% confidence interval [CI]: 0.48–0.91, P=0.010. Both in-hospital and midterm mortality did not differ significantly between the IABP use group and no IABP use group (in-hospital: OR 0.87, 95% CI: 0.59–1.28, P=0.479; midterm: OR 1.12, 95% CI: 0.53–2.38, P=0.768. IABP insertion was not associated with the risk reduction of reinfarction, recurrent ischemia, or new heart failure. However, IABP use increased the risk of severe bleeding requiring blood transfusion (OR 2.05, 95% CI: 1.29–3.25, P=0.002 and stroke (OR 1.71, 95% CI: 1.04–2.82, P=0.035. In the thrombolytic therapy and cardiogenic shock subgroups, reduced mortality rates following IABP use were observed.Conclusion: IABP insertion is associated with feasible benefits with respect to long

  11. Comparison of the short-term efficacy between docetaxel plus carboplatin and 5-fluorouracil plus carboplatin in locoregionally advanced nasopharyngeal carcinoma

    Directory of Open Access Journals (Sweden)

    Lv X

    2016-08-01

    Full Text Available Xing Lv,1,2,* Wei-Xiong Xia,1,2,* Liang-Ru Ke,1,2 Jing Yang,1,2 Wen-Zhe Qiu,1,2 Ya-Hui Yu,1,2 Hu Liang,1,2 Xin-Jun Huang,1,2 Guo-Yin Liu,1,2 Qi Zeng,1,2 Xiang Guo,1,2 Yan-Qun Xiang1,2 1Key Laboratory of Oncology in South China, 2Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China *These authors contributed equally to this work Objective: Platinum-based chemotherapy in combination with radiotherapy is a standard treatment strategy for locoregionally advanced nasopharyngeal carcinoma (NPC. This study aimed to investigate the long-term efficacy and tolerability of inductive chemotherapy with docetaxel plus carboplatin (TC or 5-fluorouracil plus carboplatin (FC followed by concurrent radiation therapy in patients with NPC. Methods: Patients (N=88 were randomized to receive TC or FC as inductive therapy followed by concurrent radiotherapy (60–70 Gy with two cycles of carboplatin (area under the curve =5 mg·h/L. Patients were followed up for 8 years. Primary end point was progression-free survival (PFS. Secondary end points included overall survival (OS, toxicity, tumor response, distant metastasis-free survival, and local recurrence-free survival. Results: At the end of the follow-up period, 31 patients died, 32 had disease progression, eleven had cancer recurrence, and 25 had distant metastasis. Overall, there was no difference between treatment groups with regard to response or survival. We found that following induction and concurrent chemoradiotherapy, the majority of patients showed a complete response (~96%–98% for induction therapy and 82%–84% for comprehensive therapy to both therapies. PFS and OS were also similar between groups. The rate of PFS was 63.6% for both FC and TC and that of OS was 65.9% and 63.5%, respectively. The overall incidence of grade 3–4 adverse events in the TC group (20.5% was higher than in the FC group (10.7%. Neutropenia and leukopenia

  12. The variation of molybdenum isotopes within the weathering system of the black shales

    Science.gov (United States)

    Jianming, Z.

    2016-12-01

    Jian-Ming Zhu 1,2, De-Can Tan 2, Liang Liang 2, Wang Jing21 State Key Laboratory of Geological Processes and Mineral Resources, China University of Geosciences, Beijing, 100083, China 2 State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang, 550002, China Molybdenum (Mo) stable isotopes have been developed as a tracer to indicate the evolution of the atmospheric and oceanic oxygenation related with continent weathering, and to reveal the extent of ancient oceanic euxinia. Molybdenum isotopic variation within the weathering system of basalts has been studied, and was presented the whole trend with heavier isotopes preferentially removed during weathering processes. However, there are few researches to study the variation of Mo isotopes during black shale weathering, especiall on the behavoir of Mo isotopes within the perfect shales' profiles. Here, the weathering profiles of Mo and selenium(Se)-rich carbonaceous rocks in Enshi southwest Hubei Province were selected. The Mo isotopes was measured on Nu Plasma II's MC-ICP-MS using 97Mo-100Mo double spike, and δ98/95Mo was reported relative to NIST 3134. A comprehensive set of Mo isotopic composition and concentration data from the unweathered, weakly and intensely weathered rocks were collected. The δ98/95Mo in fresh shales (220±248 mg/kg Mo, 1SD, n=41) from Shadi and Yutangba drill cores varies from 0.41‰ to 0.99‰ with an average of 0.67±0.16‰, while the strongly weathered shales (19.9±5.8 mg/kg Mo, 1SD, n=5) from Shadi profiles are isotopically heavier with average δ98/95Mo values of 1.03±0.10‰ (1SD, n=5). The Locally altered shales exposed in a quarry at Yutangba are highly enriched in Mo, varing from 31 to 2377 mg/kg with an average of 428 ±605mg/kg (1SD, n=24), approximately 2 times greater than that in fresh shales samples. These rocks are presented a significant variation in δ98/95Mo values varing from -0.24 ‰ to -3.99 ‰ with

  13. Treating advanced non-small-cell lung cancer in Chinese patients: focus on icotinib

    Directory of Open Access Journals (Sweden)

    Liang JL

    2014-05-01

    Full Text Available Jun-Li Liang,1 Xiao-Cang Ren,2 Qiang Lin2 1Department of Radiation Oncology, Hebei Medical University Fourth Hospital, Shijiazhuang, People’s Republic of China; 2Department of Oncology, North China Petroleum Bureau General Hospital of Hebei Medical University, Renqiu, Hebei Province, People’s Republic of China Abstract: Icotinib hydrochloride is an orally administered small-molecule reversible tyrosine kinase inhibitor that has been independently researched and developed and has independent intellectual property rights in the People’s Republic of China. Clinical trials have demonstrated that the response to icotinib among advanced non-small-cell lung cancer (NSCLC patients who received at least one platinum-based chemotherapy regimen was not inferior to gefitinib. Since being launched August 2011 in the People’s Republic of China, icotinib has been widely used in clinics, and has become an important treatment option for Chinese patients with advanced NSCLC. The present study presents the Phase I, II, and III clinical trials of icotinib and discusses current clinical applications in the People’s Republic of China and future research directions. Keywords: targeted therapy, EGFR-TKI, NSCLC

  14. The avian fossil record in Insular Southeast Asia and its implications for avian biogeography and palaeoecology

    Directory of Open Access Journals (Sweden)

    Hanneke J.M. Meijer

    2014-03-01

    Full Text Available Excavations and studies of existing collections during the last decades have significantly increased the abundance as well as the diversity of the avian fossil record for Insular Southeast Asia. The avian fossil record covers the Eocene through the Holocene, with the majority of bird fossils Pleistocene in age. Fossil bird skeletal remains represent at least 63 species in 54 genera and 27 families, and two ichnospecies are represented by fossil footprints. Birds of prey, owls and swiftlets are common elements. Extinctions seem to have been few, suggesting continuity of avian lineages since at least the Late Pleistocene, although some shifts in species ranges have occurred in response to climatic change. Similarities between the Late Pleistocene avifaunas of Flores and Java suggest a dispersal route across southern Sundaland. Late Pleistocene assemblages of Niah Cave (Borneo and Liang Bua (Flores support the rainforest refugium hypothesis in Southeast Asia as they indicate the persistence of forest cover, at least locally, throughout the Late Pleistocene and Holocene.

  15. Taxonomic Review Of The Genus Yunnantettix (Orthoptera, Tetrigidae From The Oriental Region

    Directory of Open Access Journals (Sweden)

    Storozhenko S. Yu.

    2015-06-01

    Full Text Available Taxonomic review of the genus Yunnantettix Zheng, 1995 is given. It is similar to Aspiditettix Liang, 2009, Pseudepitettix Zheng, 1995, and Epitettix Hancock, 1907. Yunnantettix is the most similar to Aspiditettix in the general appearance, the rugose disc of the pronotum, and the bisinuate lateral lobe of the pronotum, and diff erent from it by the completely reduced hind wing and the position of the antennal socket. Yunnantettix is similar to Pseudepitettix and Epitettix in the moderately widened frontal ridge and low median carina of pronotum, but diff erent from the latter by the presence of the narrow tegmen and a shallow yet distinct tegminal (upper sinus on the pronotal lateral lobe. Originally, Yunnantettix is a monotypic genus (type species: Yunnantettix bannaensis Zheng, 1995 from South China. Two species are additionally included to this genus: Yunnantettix elytratus (Günther, 1939, comb. n. (= Epitettix elytratus Günther, 1939 from India and Yunnantettix thaicus, sp. n. from Th ailand. Th e new species diff ers from all other species of this genus by the shallow excision on apex of the posterior pronotal process and by the external lateral pronotal carina, arch-like and strongly curved upward above the tegmen. A key to the species and redescription of the genus Yunnantettix are provided.

  16. Obtaining Hartree-Fock and density functional theory doubly excited states with Car-Parrinello density matrix search

    Science.gov (United States)

    Liang, Wenkel; Isborn, Christine M.; Li, Xiaosong

    2009-11-01

    The calculation of doubly excited states is one of the major problems plaguing the modern day excited state workhorse methodology of linear response time dependent Hartree-Fock (TDHF) and density function theory (TDDFT). We have previously shown that the use of a resonantly tuned field within real-time TDHF and TDDFT is able to simultaneously excite both the α and β electrons to achieve the two-electron excited states of minimal basis H2 and HeH+ [C. M. Isborn and X. Li, J. Chem. Phys. 129, 204107 (2008)]. We now extend this method to many electron systems with the use of our Car-Parrinello density matrix search (CP-DMS) with a first-principles fictitious mass method for wave function optimization [X. Li, C. L. Moss, W. Liang, and Y. Feng, J. Chem. Phys. 130, 234115 (2009)]. Real-time TDHF/TDDFT is used during the application of the laser field perturbation, driving the electron density toward the doubly excited state. The CP-DMS method then converges the density to the nearest stationary state. We present these stationary state doubly excited state energies and properties at the HF and DFT levels for H2, HeH+, lithium hydride, ethylene, and butadiene.

  17. A new moving strategy for the sequential Monte Carlo approach in optimizing the hydrological model parameters

    Science.gov (United States)

    Zhu, Gaofeng; Li, Xin; Ma, Jinzhu; Wang, Yunquan; Liu, Shaomin; Huang, Chunlin; Zhang, Kun; Hu, Xiaoli

    2018-04-01

    Sequential Monte Carlo (SMC) samplers have become increasing popular for estimating the posterior parameter distribution with the non-linear dependency structures and multiple modes often present in hydrological models. However, the explorative capabilities and efficiency of the sampler depends strongly on the efficiency in the move step of SMC sampler. In this paper we presented a new SMC sampler entitled the Particle Evolution Metropolis Sequential Monte Carlo (PEM-SMC) algorithm, which is well suited to handle unknown static parameters of hydrologic model. The PEM-SMC sampler is inspired by the works of Liang and Wong (2001) and operates by incorporating the strengths of the genetic algorithm, differential evolution algorithm and Metropolis-Hasting algorithm into the framework of SMC. We also prove that the sampler admits the target distribution to be a stationary distribution. Two case studies including a multi-dimensional bimodal normal distribution and a conceptual rainfall-runoff hydrologic model by only considering parameter uncertainty and simultaneously considering parameter and input uncertainty show that PEM-SMC sampler is generally superior to other popular SMC algorithms in handling the high dimensional problems. The study also indicated that it may be important to account for model structural uncertainty by using multiplier different hydrological models in the SMC framework in future study.

  18. Trajectory averaging for stochastic approximation MCMC algorithms

    KAUST Repository

    Liang, Faming

    2010-10-01

    The subject of stochastic approximation was founded by Robbins and Monro [Ann. Math. Statist. 22 (1951) 400-407]. After five decades of continual development, it has developed into an important area in systems control and optimization, and it has also served as a prototype for the development of adaptive algorithms for on-line estimation and control of stochastic systems. Recently, it has been used in statistics with Markov chain Monte Carlo for solving maximum likelihood estimation problems and for general simulation and optimizations. In this paper, we first show that the trajectory averaging estimator is asymptotically efficient for the stochastic approximation MCMC (SAMCMC) algorithm under mild conditions, and then apply this result to the stochastic approximation Monte Carlo algorithm [Liang, Liu and Carroll J. Amer. Statist. Assoc. 102 (2007) 305-320]. The application of the trajectory averaging estimator to other stochastic approximationMCMC algorithms, for example, a stochastic approximation MLE algorithm for missing data problems, is also considered in the paper. © Institute of Mathematical Statistics, 2010.

  19. A universal order underlying the pseudogap regime of the underdoped high Tc cuprates

    Science.gov (United States)

    Harrison, Neil

    2014-03-01

    A major achievement in condensed matter physics in the last quarter century has been a step towards the understanding of the unconventional d-wave superconducting state in the copper-oxide materials. Surprisingly, the normal state out of which the superconducting state emerges remains a mystery at low charge carrier densities, i.e., in the underdoped regime. This regime is of particular interest because it is characterised by an unusual momentum dependent energy pseudogap in the excitation spectrum that has defied explanation and is key to a full understanding of the unconventional d-wave superconducting state. I will present new quantum oscillation experimental results within the pseudogap regime of the high Tc superconductors YBa2Cu3O6+x and YBa2Cu4O8 which now extend up to the optimally-doped regime. These data reveal the evolution of the Fermi surface approaching the putative quantum critical point under the superconducting dome. A comprehensive angle-resolved study of the Fermi surface enables us to unambiguously identify a specific form of order that accounts for the observed quantum oscillations as well as other spectroscopic, transport and thermodynamic probes within the pseudogap regime. The author would like to thank B. Ramshaw, S. Sebastian, F. Balakirev, C. Mielke, M. Altarawneh, P. Goddard, S. Sabok, B. Babrowski, D. Bonn, W. Hardy, R. Liang and G. Lonzarich. This work was supported by the DOE BES ``Science of 100 tesla'' project and by the NSF and Florida State.

  20. Quantum oscillations and nodal pockets from Fermi surface reconstruction in the underdoped cuprates

    Science.gov (United States)

    Harrison, Neil

    2012-02-01

    Fermiology in the underdoped high Tc cuprates presents us with unique challenges, requiring experimentalists to look deeper into the data than is normally required for clues. Recent measurements of an oscillatory chemical potential affecting the oscillations at high magnetic fields provide a strong indication of a single type of carrier pocket. When considered in conjunction with photoemission and specific heat measurements, a Fermi surface comprised almost entirely of nodal pockets is suggested. The mystery of the Fermi surface is deepened, however, by a near doping-independent Fermi surface cross-sectional area and negative Hall and Seebeck coefficients. We explore ways in which these findings can be reconciled, taking an important hint from the diverging effective mass yielded by quantum oscillations at low dopings. The author wishes to thank Suchitra Sebastian, Moaz Atarawneh, Doug Bonn, Walter Hardy, Ruixing Liang, Charles Mielke and Gilbert Lonzarich who have contributed to this work. The work is supported by the NSF through the NHMFL and by the DOE project ``Science at 100 tesla.''

  1. Pituitary abscess: report of two cases and review of the literature

    Directory of Open Access Journals (Sweden)

    Liu Y

    2017-06-01

    Full Text Available Yu Liu,1 Feng Liu,2 Qi Liang,3 Yexin Li,4 Zhifei Wang5 1Department of Neurosurgery, The Third Xiangya Hospital, Central South University, Changsha, 2Department of Neurosurgery, The Third Xiangya Hospital, Central South University, Changsha, 3Department of Radiology, The Third Xiangya Hospital, Central South University, Changsha, 4Department of Neurosurgery, The Central Hospital of Shaoyang, Shaoyang, 5Department of Neurosurgery, The Third Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China Abstract: Pituitary abscess is a rare but critical disorder caused by an infectious process where purulent material accumulates inside the sella turcica. Since symptoms, signs and radiographic characteristics of pituitary abscess are similar to several other pituitary lesions, correct diagnosis before surgery is challenging. In this article, two cases of pituitary abscess treated in our department are reported, followed by a literature review. In these two cases, both patients presented with intermittent fever. Magnetic resonance imaging revealed a suprasellar lesion with rim enhancement after contrast injection. After transsphenoidal surgery, the diagnosis of pituitary abscess was confirmed. The patients were then given antibiotic treatment and recovered fully in less than 2 months. Findings of this article support timely diagnosis and proper treatment including transsphenoidal surgery and antibiotic therapy for pituitary abscess, leading to lower mortality rates and higher probability of pituitary hormone function recovery. Keywords: pituitary abscess, transsphenoidal resection, antibiotic therapy, diagnosis 

  2. Promoting Secondary Analysis of Electronic Medical Records in China: Summary of the PLAGH-MIT Critical Data Conference and Health Datathon.

    Science.gov (United States)

    Li, Peiyao; Xie, Chen; Pollard, Tom; Johnson, Alistair Edward William; Cao, Desen; Kang, Hongjun; Liang, Hong; Zhang, Yuezhou; Liu, Xiaoli; Fan, Yong; Zhang, Yuan; Xue, Wanguo; Xie, Lixin; Celi, Leo Anthony; Zhang, Zhengbo

    2017-11-14

    Electronic health records (EHRs) have been widely adopted among modern hospitals to collect and track clinical data. Secondary analysis of EHRs could complement the traditional randomized control trial (RCT) research model. However, most researchers in China lack either the technical expertise or the resources needed to utilize EHRs as a resource. In addition, a climate of cross-disciplinary collaboration to gain insights from EHRs, a crucial component of a learning healthcare system, is not prevalent. To address these issues, members from the Massachusetts Institute of Technology (MIT) and the People's Liberation Army General Hospital (PLAGH) organized the first clinical data conference and health datathon in China, which provided a platform for clinicians, statisticians, and data scientists to team up and address information gaps in the intensive care unit (ICU). ©Peiyao Li, Chen Xie, Tom Pollard, Alistair Edward William Johnson, Desen Cao, Hongjun Kang, Hong Liang, Yuezhou Zhang, Xiaoli Liu, Yong Fan, Yuan Zhang, Wanguo Xue, Lixin Xie, Leo Anthony Celi, Zhengbo Zhang. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 14.11.2017.

  3. Impact of strabismus on the quality of life of Chinese Han teenagers

    Directory of Open Access Journals (Sweden)

    Tu CS

    2016-06-01

    Full Text Available Changsen Tu, Liang Ye, Longfei Jiang, Yuwen Wang, Yingzi Li The Eye Hospital of Wenzhou Medical University, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, People’s Republic of China Background: Although much research has been conducted on the impact of strabismus on the quality of life (QoL of adults, the effect of this condition on teenagers has not been extensively studied. This study therefore aimed to assess the effect of strabismus on the vision-related QoL of Chinese teenagers.Methods: The Chinese version of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25 was self-administered by 1,040 teenagers with strabismus and 1,002 individuals with normal vision. All the participants were from the Chinese Han population. The independent samples t-test was used to compare QoL between teenagers with and without strabismus.Results: The majority of scores on the NEI-VFQ-25 domains were significantly different between the two groups. QoL was significantly lower in individuals with strabismus compared with teenagers with normal vision on all domains, with the exception of social functioning.Conclusion: Statistically significantly lower vision-related QoL scores were found in Chinese Han teenagers with strabismus compared with those without strabismus. Keywords: quality of life, strabismus, NEI-VFQ-25, teenager, HRQoL

  4. Malignant thrombosis of the superior vena cava caused by non-small-cell lung cancer treated with radiation and erlotinib: a case with complete and prolonged response over 3 years

    Directory of Open Access Journals (Sweden)

    Wang JY

    2013-07-01

    Full Text Available Jianyang Wang,1 Jun Liang,1 Wenqing Wang,1 Han Ouyang,2 Luhua Wang11Department of Radiation Oncology, Cancer Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 2Department of Diagnostic Radiology, Cancer Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of ChinaAbstract: Most cases of superior vena cava (SVC syndrome resulting from neoplasm, especially from lung cancer, remain a serious challenge to treat. Here, for the first time as far as we are aware, we report the case of a non-small-cell lung cancer patient with a massive SVC malignant thrombosis who was treated with thoracic irradiation and erlotinib. The treatment regimen consisted of erlotinib 150 mg/day and a total dose of 66 Gy/33 fractions delivered to the tumor, malignant thrombosis, and metastasis mediastinal lymph nodes. The malignant thrombosis responded dramatically and the combined regimen was well tolerated. After discharge, the erlotinib was prescribed as maintenance therapy. The patient was followed closely for the next 3 years. During this time, positron emission tomography/computed tomography scans and serum tumor marker screens were undertaken. By 6 months, the primary tumor showed complete response and by 9 months, the SVC thrombosis had disappeared. No sign of relapse has been found to date.Keywords: superior vena cava syndrome, radiotherapy, thoracic irradiation, neoplasm

  5. A Provably-Secure Transmission Scheme for Wireless Body Area Networks.

    Science.gov (United States)

    Omala, Anyembe Andrew; Robert, Niyifasha; Li, Fagen

    2016-11-01

    Wireless body area network (WBANs) is composed of sensors that collect and transmit a person's physiological data to health-care providers in real-time. In order to guarantee security of this data over open networks, a secure data transmission mechanism between WBAN and application provider's servers is of necessity. Modified medical data does not provide a true reflection of an individuals state of health and its subsequent use for diagnosis could lead to an irreversible medical condition. In this paper, we propose a lightweight certificateless signcryption scheme for secure transmission of data between WBAN and servers. Our proposed scheme not only provides confidentiality of data and authentication in a single logical step, it is lightweight and resistant to key escrow attacks. We further provide security proof that our scheme provides indistinguishability against adaptive chosen ciphertext attack and unforgeability against adaptive chosen message attack in random oracle model. Compared with two other Diffie-Hellman based signcryption schemes proposed by Barbosa and Farshim (BF) and another by Yin and Liang (YL), our scheme consumes 46 % and 8 % less energy during signcryption than BF and YL scheme respectively.

  6. Stochastic approximation Monte Carlo importance sampling for approximating exact conditional probabilities

    KAUST Repository

    Cheon, Sooyoung

    2013-02-16

    Importance sampling and Markov chain Monte Carlo methods have been used in exact inference for contingency tables for a long time, however, their performances are not always very satisfactory. In this paper, we propose a stochastic approximation Monte Carlo importance sampling (SAMCIS) method for tackling this problem. SAMCIS is a combination of adaptive Markov chain Monte Carlo and importance sampling, which employs the stochastic approximation Monte Carlo algorithm (Liang et al., J. Am. Stat. Assoc., 102(477):305-320, 2007) to draw samples from an enlarged reference set with a known Markov basis. Compared to the existing importance sampling and Markov chain Monte Carlo methods, SAMCIS has a few advantages, such as fast convergence, ergodicity, and the ability to achieve a desired proportion of valid tables. The numerical results indicate that SAMCIS can outperform the existing importance sampling and Markov chain Monte Carlo methods: It can produce much more accurate estimates in much shorter CPU time than the existing methods, especially for the tables with high degrees of freedom. © 2013 Springer Science+Business Media New York.

  7. Generalized SMO algorithm for SVM-based multitask learning.

    Science.gov (United States)

    Cai, Feng; Cherkassky, Vladimir

    2012-06-01

    Exploiting additional information to improve traditional inductive learning is an active research area in machine learning. In many supervised-learning applications, training data can be naturally separated into several groups, and incorporating this group information into learning may improve generalization. Recently, Vapnik proposed a general approach to formalizing such problems, known as "learning with structured data" and its support vector machine (SVM) based optimization formulation called SVM+. Liang and Cherkassky showed the connection between SVM+ and multitask learning (MTL) approaches in machine learning, and proposed an SVM-based formulation for MTL called SVM+MTL for classification. Training the SVM+MTL classifier requires the solution of a large quadratic programming optimization problem which scales as O(n(3)) with sample size n. So there is a need to develop computationally efficient algorithms for implementing SVM+MTL. This brief generalizes Platt's sequential minimal optimization (SMO) algorithm to the SVM+MTL setting. Empirical results show that, for typical SVM+MTL problems, the proposed generalized SMO achieves over 100 times speed-up, in comparison with general-purpose optimization routines.

  8. Are ovarian cancer stem cells the target for innovative immunotherapy?

    Directory of Open Access Journals (Sweden)

    Wang L

    2018-05-01

    Full Text Available Liang Wang, Tianmin Xu, Manhua Cui Department of Gynecology and Obstetrics, The Second Hospital of Jilin University, Changchun, Jilin, People’s Republic of China Abstract: Cancer stem cells (CSCs, a subpopulation of cancer cells with the ability of self-renewal and differentiation, are believed to be responsible for tumor generation, progression, metastasis, and relapse. Ovarian cancer, the most malignant gynecological cancer, has consistent pathology behavior with CSC model, which suggests that therapies based on ovarian cancer stem cells (OCSCs can gain a more successful prognosis. Much evidence has proved that epigenetic mechanism played an important role in tumor formation and sustainment. Since CSCs are generally resistant to conventional therapies (chemotherapy and radiotherapy, immunotherapy is a more effective method that has been implemented in the clinic. Chimeric antigen receptor (CAR- T cell, an adoptive cellular immunotherapy, which results in apparent elimination of tumor in both hematologic and solid cancers, could be used for ovarian cancer. This review covers the basic conception of CSCs and OCSCs, the implication of epigenetic mechanism underlying cancer evolution considering CSC model, the immunotherapies reported for ovarian cancer targeting OCSCs currently, and the relationship between immune system and hierarchy cancer organized by CSCs. Particularly, the promising prospects and potential pitfalls of targeting OCSC surface markers to design CAR-T cellular immunotherapy are discussed here. Keywords: cancer stem cells, ovarian cancer, epigenetics, tumor cell surface marker, immunotherapy, CAR

  9. Aminoclay–lipid hybrid composite as a novel drug carrier of fenofibrate for the enhancement of drug release and oral absorption

    Directory of Open Access Journals (Sweden)

    Yang L

    2016-03-01

    Full Text Available Liang Yang, Yating Shao, Hyo-Kyung Han BK Plus Project Team, College of Pharmacy, Dongguk University, Goyang, South Korea Abstract: This study aimed to prepare the aminoclay–lipid hybrid composite to enhance the drug release and improve the oral bioavailability of poorly water-soluble fenofibrate. Antisolvent precipitation coupled with an immediate freeze-drying method was adopted to incorporate fenofibrate into aminoclay–lipid hybrid composite (ALC. The optimal composition of the ALC formulation was determined as the ratios of aminoclay to krill oil of 3:1 (w/w, krill oil to fenofibrate of 2:1 (w/w, and antisolvent to solvent of 6:4 (v/v. The morphological characteristics of ALC formulation were determined using scanning electron microscopy, differential scanning calorimetry, and X-ray powder diffraction, which indicated microcrystalline state of fenofibrate in ALC formulation. The ALC formulation achieved almost complete dissolution within 30 minutes, whereas the untreated powder and physical mixture exhibited less than 15% drug release. Furthermore, ALC formulation effectively increased the peak plasma concentration (Cmax and area under the curve (AUC of fenofibric acid (an active metabolite in rats by approximately 13- and seven-fold, respectively. Furthermore, ALC formulation exhibited much lower moisture sorption behavior than the lyophilized formulation using sucrose as a cryoprotectant. Taken together, the present findings suggest that ALC formulation is promising for improving the oral absorption of poorly soluble fenofibrate. Keywords: aminoclay, omega-3 phospholipids, fenofibrate, drug release, oral absorption 

  10. Mean-Eddy-Turbulence Interaction through Canonical Transfer Analysis: Theory and Application to the Kuroshio Extension Energetics Study

    Science.gov (United States)

    Liang, X. S.

    2016-02-01

    Central at the processes of mean-eddy-turbulence interaction, e.g., mesoscale eddy shedding, relaminarization, etc., is the transfer of energy among different scales. The existing classical transfers, however, do not take into account the issue of energy conservation and, therefore, are not faithful representations of the real interaction processes, which are fundamentally a redistribution of energy among scales. Based on a new analysis machinery, namely, multiscale window transform (Liang and Anderson, 2007), we were able to obtain a formula for this important processes, with the property of energy conservation a naturally embedded property. This formula has a form reminiscent of the Poisson bracket in Hamiltonian dynamics. It has been validated with many benchmark processes, and, particularly, has been applied with success to control the eddy shedding behind a bluff body. Presented here will be an application study of the instabilities and mean-eddy interactions in the Kuroshio Extension (KE) region. Generally, it is found that the unstable KE jet fuels the mesoscale eddies, but in the offshore eddy decaying region, the cause-effect relation reverses: it is the latter that drive the former. On the whole the eddies act to decelerate the jet in the upstream, whereas accelerating it downstream.

  11. Petal Thicknesses and Shape Transformations in Blooming Lilies

    Energy Technology Data Exchange (ETDEWEB)

    Portet, Thomas; Holmes, Peter N.; Bowden, Mark E.; Stephens, Sean A.; Varga, Tamas; Keller, Sarah L.

    2013-01-29

    During blooming, flower petals undergo significant shape changes. For lilies, various different mechanisms responsible for the change have been suggested [1,2]. One is that cell growth along the edge of a petal, or, more generally, a tepal, drives a transition from a cup shape (within a bud) to a saddle shape (within a bloom). This mechanism has been previously considered for tepals modeled as shallow elliptical shells whose thickness from the center, t, falls off at least as fast as t = t0 (1 - x2/a2 - y2/b2 ) [1]. Here t0 is the maximum thickness of the shell, a and b are the semimajor and semiminoraxes, x and y are the coordinates along the longitudinal and lateral axes. By measuring tepal thicknesses from images collected by x-ray tomography of intact buds and by photography of microtomed buds, we find that this condition is indeed met for both Lilium casablanca and Lilium lancifolium. [1] Liang and Mahadevan. Growth, geometry, and mechanics of a blooming lily.

  12. Primer design for a prokaryotic differential display RT-PCR.

    Science.gov (United States)

    Fislage, R; Berceanu, M; Humboldt, Y; Wendt, M; Oberender, H

    1997-05-01

    We have developed a primer set for a prokaryotic differential display of mRNA in the Enterobacteriaceae group. Each combination of ten 10mer and ten 11mer primers generates up to 85 bands from total Escherichia coli RNA, thus covering expressed sequences of a complete bacterial genome. Due to the lack of polyadenylation in prokaryotic RNA the type T11VN anchored oligonucleotides for the reverse transcriptase reaction had to be replaced with respect to the original method described by Liang and Pardee [ Science , 257, 967-971 (1992)]. Therefore, the sequences of both the 10mer and the new 11mer oligonucleotides were determined by a statistical evaluation of species-specific coding regions extracted from the EMBL database. The 11mer primers used for reverse transcription were selected for localization in the 3'-region of the bacterial RNA. The 10mer primers preferentially bind to the 5'-end of the RNA. None of the primers show homology to rRNA or other abundant small RNA species. Randomly sampled cDNA bands were checked for their bacterial origin either by re-amplification, cloning and sequencing or by re-amplification and direct sequencing with 10mer and 11mer primers after asymmetric PCR.

  13. Male occult triple-negative breast cancer with dermatomyositis: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Zhang L

    2017-11-01

    Full Text Available Le Zhang,1 Chenghua Zhang,2 Zhaoying Yang,1 Miao He,3 Lijuan Zhang,1 Shereen Ezzat,4 Xi Liang5 1Department of Breast Surgery, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China; 2Endoscopy Department, Jilin Cancer Hospital, Changchun, Jilin,China; 3Department of Anesthesia, The Second Hospital of Jilin University, Changchun, Jilin, China; 4Ontario Cancer Institute and The Endocrine Oncology Site Group, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada; 5Department of Breast Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China Abstract: Occult breast cancer is defined by the presence of axillary metastases without an identifiable primary breast tumor. Here, we report a rare case of a male occult breast cancer with dermatomyositis. We performed a modified radical mastectomy consisting of whole breast mastectomy and axillary lymph node dissection. Immunohistochemistry and fluorescent in situ hybridization analyses demonstrated an adenocarcinoma likely of breast origin, which was an occult triple-negative breast cancer. Interestingly, the patient’s previously noted periorbital dermatomyositis resolved promptly following surgical excision. Keywords: male breast cancer, occult breast cancer, triple-negative breast cancer, dermato­myositis 

  14. Dependency distance distribution - from the perspective of genre variation. Comment on "Dependency distance: a new perspective on syntactic patterns in natural languages" by Haitao Liu et al.

    Science.gov (United States)

    Wang, Yaqin

    2017-07-01

    Language can be regarded as a system where different components fit together, according to Saussure [1]. Likewise, the central axiom of synergetic linguistic is that language is a self-organized and self-adapting system. One of its main concerns is to view language as ;a psycho-social phenomenon and a biological-cognitive one at the same time; [2, 760]. Based on this assumption, Liu, Xu and Liang propose a novel approach, i.e., dependency distance, to study the general tendency hidden beneath diverse human languages [3]. As the authors describe in sections 1-3, variations within and between human languages all show the similar tendency towards dependency distance minimization (DDM). In sections 4-5, they introduce certain syntactic patterns related to both short and long dependency distances. However, the effect of genre seems to be given less sufficient attention by the authors. A study suggests that different distributions of closeness and degree centralities across genres can broaden the understanding of dependency distance distribution [4]. Another one shows that different genres have different parameters in terms of modeling dependency distance distribution [5]. Further research on the genre variation, therefore, can provide additional support for this issue.

  15. Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice

    Directory of Open Access Journals (Sweden)

    Yi Liu

    2017-04-01

    Full Text Available Summary: Natural genetic diversity offers an important yet largely untapped resource to decipher the molecular mechanisms regulating hematopoietic stem cell (HSC function. Latexin (Lxn is a negative stem cell regulatory gene identified on the basis of genetic diversity. By using an Lxn knockout mouse model, we found that Lxn inactivation in vivo led to the physiological expansion of the entire hematopoietic hierarchy. Loss of Lxn enhanced the competitive repopulation capacity and survival of HSCs in a cell-intrinsic manner. Gene profiling of Lxn-null HSCs showed altered expression of genes enriched in cell-matrix and cell-cell interactions. Thrombospondin 1 (Thbs1 was a potential downstream target with a dramatic downregulation in Lxn-null HSCs. Enforced expression of Thbs1 restored the Lxn inactivation-mediated HSC phenotypes. This study reveals that Lxn plays an important role in the maintenance of homeostatic hematopoiesis, and it may lead to development of safe and effective approaches to manipulate HSCs for clinical benefit. : In this article, Liang and colleagues show that loss of latexin in vivo expands the HSC population and increases their survival and engraftment. Latexin regulates HSC function and hematopoiesis via the Thbs1 signaling pathway. Keywords: latexin, hematopoietic stem cell, repopulating advantage, expansion, survival, thrombospondin 1

  16. Archaeology and age of a new hominin from Flores in eastern Indonesia.

    Science.gov (United States)

    Morwood, M J; Soejono, R P; Roberts, R G; Sutikna, T; Turney, C S M; Westaway, K E; Rink, W J; Zhao, J-X; van den Bergh, G D; Due, Rokus Awe; Hobbs, D R; Moore, M W; Bird, M I; Fifield, L K

    2004-10-28

    Excavations at Liang Bua, a large limestone cave on the island of Flores in eastern Indonesia, have yielded evidence for a population of tiny hominins, sufficiently distinct anatomically to be assigned to a new species, Homo floresiensis. The finds comprise the cranial and some post-cranial remains of one individual, as well as a premolar from another individual in older deposits. Here we describe their context, implications and the remaining archaeological uncertainties. Dating by radiocarbon (14C), luminescence, uranium-series and electron spin resonance (ESR) methods indicates that H. floresiensis existed from before 38,000 years ago (kyr) until at least 18 kyr. Associated deposits contain stone artefacts and animal remains, including Komodo dragon and an endemic, dwarfed species of Stegodon. H. floresiensis originated from an early dispersal of Homo erectus (including specimens referred to as Homo ergaster and Homo georgicus) that reached Flores, and then survived on this island refuge until relatively recently. It overlapped significantly in time with Homo sapiens in the region, but we do not know if or how the two species interacted.

  17. Early stone technology on Flores and its implications for Homo floresiensis.

    Science.gov (United States)

    Brumm, Adam; Aziz, Fachroel; van den Bergh, Gert D; Morwood, Michael J; Moore, Mark W; Kurniawan, Iwan; Hobbs, Douglas R; Fullagar, Richard

    2006-06-01

    In the Soa Basin of central Flores, eastern Indonesia, stratified archaeological sites, including Mata Menge, Boa Lesa and Kobatuwa (Fig. 1), contain stone artefacts associated with the fossilized remains of Stegodon florensis, Komodo dragon, rat and various other taxa. These sites have been dated to 840-700 kyr bp (thousand years before present). The authenticity of the Soa Basin artefacts and their provenance have been demonstrated by previous work, but to quell lingering doubts, here we describe the context, attributes and production modes of 507 artefacts excavated at Mata Menge. We also note specific similarities, and apparent technological continuity, between the Mata Menge stone artefacts and those excavated from Late Pleistocene levels at Liang Bua cave, 50 km to the west. The latter artefacts, dated to between 95-74 and 12 kyr ago, are associated with the remains of a dwarfed descendent of S. florensis, Komodo dragon, rat and a small-bodied hominin species, Homo floresiensis, which had a brain size of about 400 cubic centimetres. The Mata Menge evidence negates claims that stone artefacts associated with H. floresiensis are so complex that they must have been made by modern humans (Homo sapiens).

  18. On calculating the probability of a set of orthologous sequences

    Directory of Open Access Journals (Sweden)

    Junfeng Liu

    2009-02-01

    Full Text Available Junfeng Liu1,2, Liang Chen3, Hongyu Zhao4, Dirk F Moore1,2, Yong Lin1,2, Weichung Joe Shih1,21Biometrics Division, The Cancer, Institute of New Jersey, New Brunswick, NJ, USA; 2Department of Biostatistics, School of Public Health, University of Medicine and Dentistry of New Jersey, Piscataway, NJ, USA; 3Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA; 4Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USAAbstract: Probabilistic DNA sequence models have been intensively applied to genome research. Within the evolutionary biology framework, this article investigates the feasibility for rigorously estimating the probability of a set of orthologous DNA sequences which evolve from a common progenitor. We propose Monte Carlo integration algorithms to sample the unknown ancestral and/or root sequences a posteriori conditional on a reference sequence and apply pairwise Needleman–Wunsch alignment between the sampled and nonreference species sequences to estimate the probability. We test our algorithms on both simulated and real sequences and compare calculated probabilities from Monte Carlo integration to those induced by single multiple alignment.Keywords: evolution, Jukes–Cantor model, Monte Carlo integration, Needleman–Wunsch alignment, orthologous

  19. Anti-Fungal Activity and Allelopathic Influence of Vitex agnus-castus L. (Verbenaceae Essential Oils on Actinidia deliciosa in vitro Culture

    Directory of Open Access Journals (Sweden)

    N. Ya. Levchyk

    2016-12-01

    Full Text Available The results of research of Vitex agnus-castus L. plants from the collection of M. M. Gryshko National Botanical Garden, NAS of Ukraine are given. The species belongs to a group of prospective essential oil plants which are characterized by valuable medicinal, food, aromatic, honey, technical and decorative properties, and can be used in many industries, including pharmaceutical, cosmetic and food. The quantitative content and qualitative composition of the vegetating plant’s essential oil are determined, its antifungal influence on the cultures of Aspergillus niger, Alternaria alternatа andFusarium culmorum is assessed. Antifungal properties of V. agnus-castus essential oil were used to sterilize Actinidia deliciosa (A. Chev C.F. Liang & A.R. Fergusonexplants introduced in vitro. V. agnus-castusessential oil is shown to have allelopathic effect on A. deliciosa plants. The possibility of using the oil in vitro to cultivate A. deliciosa callus as a source of bioactive substances and to enhance the effectiveness of biotechnological methods of plant propagation is discussed.

  20. Yearning for the Lost Paradise: The "Great Unity" (datong and Its Philosophical Interpretations

    Directory of Open Access Journals (Sweden)

    Bart DESSEIN

    2017-01-01

    Full Text Available In the course of China’s history, the term datong (great unity has been interpreted in multiple ways. This article first discusses the concept as understood in the Liji, and then focuses on the way in which the perceived loss of the “great unity” within “all-under-heaven” (tianxia at the end of the Qing dynasty (1644–1911, and the endeavor to reconstruct the empire as a modern nation-state starting in the early twentieth century, informed the way the term datong was interpreted. After discussing the interpretations by Wang Tao (1828–1897, Hong Xiuquan (1813–1864, Kang Youwei (1858–1927, Liang Qichao (1873–1929, Sun Zhongshan (1866–1925, and Mao Zedong (1893–1976, this work concludes with a discussion on how, against the background of the perceived threat of loss of national unity that characterizes the contemporary People’s Republic of China, a New Confucian interpretation is developed.

  1. Travel advice for the immunocompromised traveler: prophylaxis, vaccination, and other preventive measures

    Directory of Open Access Journals (Sweden)

    Patel RR

    2015-02-01

    Full Text Available Rupa R Patel,1 Stephen Y Liang,1 Pooja Koolwal,2 Frederick Matthew Kuhlmann1 1Division of Infectious Diseases, 2Division of Medical Education, Washington University School of Medicine, St Louis, MO, USA Abstract: Immunocompromised patients are traveling at increasing rates. Physicians caring for these complex patients must be knowledgeable in pretravel consultation and recognize when referral to an infectious disease specialist is warranted. This article outlines disease prevention associated with international travel for adults with human immunodeficiency virus, asplenia, solid organ and hematopoietic transplantation, and other immunosuppressed states. While rates of infection may not differ significantly between healthy and immunocompromised travelers, the latter are at greater risk for severe disease. A thorough assessment of these risks can ensure safe and healthy travel. The travel practitioners’ goal should be to provide comprehensive risk information and recommend appropriate vaccinations or prevention measures tailored to each patient’s condition. In some instances, live vaccines and prophylactic medications may be contraindicated. Keywords: immunocompromised, vaccines, travel, malaria, diarrhea

  2. Note: A new method for directly reducing the sampling jitter noise of the digital phasemeter

    Science.gov (United States)

    Liang, Yu-Rong

    2018-03-01

    The sampling jitter noise is one non-negligible noise source of the digital phasemeter used for space gravitational wave detection missions. This note provides a new method for directly reducing the sampling jitter noise of the digital phasemeter, by adding a dedicated signal of which the frequency, amplitude, and initial phase should be pre-set. In contrast to the phase correction using the pilot-tone in the work of Burnett, Gerberding et al., Liang et al., Ales et al., Gerberding et al., and Ware et al. [M.Sc. thesis, Luleå University of Technology, 2010; Classical Quantum Gravity 30, 235029 (2013); Rev. Sci. Instrum. 86, 016106 (2015); Rev. Sci. Instrum. 86, 084502 (2015); Rev. Sci. Instrum. 86, 074501 (2015); and Proceedings of the Earth Science Technology Conference (NASA, USA, 2006)], the new method is intrinsically additive noise suppression. The experiment results validate that the new method directly reduces the sampling jitter noise without data post-processing and provides the same phase measurement noise level (10-6 rad/Hz1/2 at 0.1 Hz) as the pilot-tone correction.

  3. A Total Variation-Based Reconstruction Method for Dynamic MRI

    Directory of Open Access Journals (Sweden)

    Germana Landi

    2008-01-01

    Full Text Available In recent years, total variation (TV regularization has become a popular and powerful tool for image restoration and enhancement. In this work, we apply TV minimization to improve the quality of dynamic magnetic resonance images. Dynamic magnetic resonance imaging is an increasingly popular clinical technique used to monitor spatio-temporal changes in tissue structure. Fast data acquisition is necessary in order to capture the dynamic process. Most commonly, the requirement of high temporal resolution is fulfilled by sacrificing spatial resolution. Therefore, the numerical methods have to address the issue of images reconstruction from limited Fourier data. One of the most successful techniques for dynamic imaging applications is the reduced-encoded imaging by generalized-series reconstruction method of Liang and Lauterbur. However, even if this method utilizes a priori data for optimal image reconstruction, the produced dynamic images are degraded by truncation artifacts, most notably Gibbs ringing, due to the spatial low resolution of the data. We use a TV regularization strategy in order to reduce these truncation artifacts in the dynamic images. The resulting TV minimization problem is solved by the fixed point iteration method of Vogel and Oman. The results of test problems with simulated and real data are presented to illustrate the effectiveness of the proposed approach in reducing the truncation artifacts of the reconstructed images.

  4. Homo floresiensis contextualized: a geometric morphometric comparative analysis of fossil and pathological human samples.

    Directory of Open Access Journals (Sweden)

    Karen L Baab

    Full Text Available The origin of hominins found on the remote Indonesian island of Flores remains highly contentious. These specimens may represent a new hominin species, Homo floresiensis, descended from a local population of Homo erectus or from an earlier (pre-H. erectus migration of a small-bodied and small-brained hominin out of Africa. Alternatively, some workers suggest that some or all of the specimens recovered from Liang Bua are pathological members of a small-bodied modern human population. Pathological conditions proposed to explain their documented anatomical features include microcephaly, myxoedematous endemic hypothyroidism ("cretinism" and Laron syndrome (primary growth hormone insensitivity. This study evaluates evolutionary and pathological hypotheses through comparative analysis of cranial morphology. Geometric morphometric analyses of landmark data show that the sole Flores cranium (LB1 is clearly distinct from healthy modern humans and from those exhibiting hypothyroidism and Laron syndrome. Modern human microcephalic specimens converge, to some extent, on crania of extinct species of Homo. However in the features that distinguish these two groups, LB1 consistently groups with fossil hominins and is most similar to H. erectus. Our study provides further support for recognizing the Flores hominins as a distinct species, H. floresiensis, whose affinities lie with archaic Homo.

  5. Homo floresiensis Contextualized: A Geometric Morphometric Comparative Analysis of Fossil and Pathological Human Samples

    Science.gov (United States)

    Baab, Karen L.; McNulty, Kieran P.; Harvati, Katerina

    2013-01-01

    The origin of hominins found on the remote Indonesian island of Flores remains highly contentious. These specimens may represent a new hominin species, Homo floresiensis, descended from a local population of Homo erectus or from an earlier (pre-H. erectus) migration of a small-bodied and small-brained hominin out of Africa. Alternatively, some workers suggest that some or all of the specimens recovered from Liang Bua are pathological members of a small-bodied modern human population. Pathological conditions proposed to explain their documented anatomical features include microcephaly, myxoedematous endemic hypothyroidism (“cretinism”) and Laron syndrome (primary growth hormone insensitivity). This study evaluates evolutionary and pathological hypotheses through comparative analysis of cranial morphology. Geometric morphometric analyses of landmark data show that the sole Flores cranium (LB1) is clearly distinct from healthy modern humans and from those exhibiting hypothyroidism and Laron syndrome. Modern human microcephalic specimens converge, to some extent, on crania of extinct species of Homo. However in the features that distinguish these two groups, LB1 consistently groups with fossil hominins and is most similar to H. erectus. Our study provides further support for recognizing the Flores hominins as a distinct species, H. floresiensis, whose affinities lie with archaic Homo. PMID:23874886

  6. 莎剧两译本中《圣经》典故翻译对比%A Comparative Study on the Two Translations of Biblical Allusions in Shakespeare's Plays

    Institute of Scientific and Technical Information of China (English)

    曹萍

    2012-01-01

    每个民族的文化中都包含着大量的典故,英语文学中来自《圣经》的典故俯拾皆是,伟大的文学家莎士比亚也不例外,莎士比亚的剧本中大量使用了出自《圣经》的典故。在翻译这些典故的时候,朱生豪和梁实秋使用了不同翻译方法,既有相同的也有不同的,各有千秋。%Allusions are found in every culture while Biblical ones pervades in English literature.Even great man of letters,William Shakespeare applied numerous Biblical allusions in his pales.In translating these allusions,the great translators Liang Shiqiu anf Zhu Shenghao employed similar and different methods and strategies.

  7. Characterization and evaluation of an oral microemulsion containing the antitumor diterpenoid compound ent-11alpha-hydroxy-15-oxo-kaur-16-en-19-oic-acid

    Directory of Open Access Journals (Sweden)

    Lu Y

    2013-05-01

    Full Text Available Yingnian Lu,1,2 Kefeng Wu,2 Li Li,2 Yuhui He,2 Liao Cui,2 Nianci Liang,2 Bozhong Mu11Department of Chemistry, East China University of Science and Technology, Shanghai, 2Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang, People’s Republic of ChinaAbstract: The objective of this study was to develop an oral microemulsion formulation of the antitumor diterpenoid agent, ent-11a-hydroxy-15-oxo-kaur-16-en-19-oic- acid (henceforth referred to as 5F, to enhance its bioavailability and evaluate its hepatotoxicity. Pseudoternary phase diagrams showed that the optimal microemulsion formulation contained 45% water, 10% castor oil as the oil phase, 15% Cremophor EL as the surfactant, and 30% as a cosurfactant mixture of 1,2-propanediol and polyethylene glycol (PEG-400 (2:1, w/w. The microemulsion preparation was characterized and its droplet diameter was within 50 nm. Release of 5F in vitro from the microemulsion was slightly increased compared with a suspension containing the same amount of active drug. Pharmacokinetic parameters in vivo indicated that bioavailability was markedly improved, with the relative bioavailability being 616.15% higher for the microemulsion than for the suspension. Toxicity tests showed that the microemulsion had no hepatotoxicity in mice. These results suggest the potential for 5F microemulsion to be administered by the oral route.Keywords: antitumor, diterpenoid, microemulsion, pharmacokinetics, toxicity

  8. Concentration-dependent effects of fullerenol on cultured hippocampal neuron viability

    Directory of Open Access Journals (Sweden)

    Zha YY

    2012-06-01

    Full Text Available Ying-ying Zha,1 Bo Yang,1 Ming-liang Tang,2 Qiu-chen Guo,1 Ju-tao Chen,1 Long-ping Wen,3 Ming Wang11CAS Key Laboratory of Brain Function and Disease, School of Life Sciences, University of Science and Technology of China, Hefei, 2Suzhou Institute of NanoTech and NanoBionics, Chinese Academy of Sciences, Suzhou, 3Laboratory of Nano-biology, School of Life Sciences, University of Science and Technology of China, Hefei, People's Republic of ChinaBackground: Recent studies have shown that the biological actions and toxicity of the water-soluble compound, polyhydroxyfullerene (fullerenol, are related to the concentrations present at a particular site of action. This study investigated the effects of different concentrations of fullerenol on cultured rat hippocampal neurons.Methods and results: Fullerenol at low concentrations significantly enhanced hippocampal neuron viability as tested by MTT assay and Hoechst 33342/propidium iodide double stain detection. At high concentrations, fullerenol induced apoptosis confirmed by Comet assay and assessment of caspase proteins.Conclusion: These findings suggest that fullerenol promotes cell death and protects against cell damage, depending on the concentration present. The concentration-dependent effects of fullerenol were mainly due to its influence on the reduction-oxidation pathway.Keywords: fullerenol, nanomaterial, neurotoxicity, neuroprotection, hippocampal neuron

  9. Stochastic approximation Monte Carlo importance sampling for approximating exact conditional probabilities

    KAUST Repository

    Cheon, Sooyoung; Liang, Faming; Chen, Yuguo; Yu, Kai

    2013-01-01

    Importance sampling and Markov chain Monte Carlo methods have been used in exact inference for contingency tables for a long time, however, their performances are not always very satisfactory. In this paper, we propose a stochastic approximation Monte Carlo importance sampling (SAMCIS) method for tackling this problem. SAMCIS is a combination of adaptive Markov chain Monte Carlo and importance sampling, which employs the stochastic approximation Monte Carlo algorithm (Liang et al., J. Am. Stat. Assoc., 102(477):305-320, 2007) to draw samples from an enlarged reference set with a known Markov basis. Compared to the existing importance sampling and Markov chain Monte Carlo methods, SAMCIS has a few advantages, such as fast convergence, ergodicity, and the ability to achieve a desired proportion of valid tables. The numerical results indicate that SAMCIS can outperform the existing importance sampling and Markov chain Monte Carlo methods: It can produce much more accurate estimates in much shorter CPU time than the existing methods, especially for the tables with high degrees of freedom. © 2013 Springer Science+Business Media New York.

  10. 辛弃疾的“事功派”思想及在稼轩词中的体现%Xin Qi-ji’s Utilitarianism Ethics Thought And influence on Jiaxuan Ci-poems

    Institute of Scientific and Technical Information of China (English)

    宋学达

    2013-01-01

    事功派哲学家陈亮与辛弃疾私交甚厚,其哲学思想必然会对辛弃疾产生影响,而历来对辛弃疾的研究中,似乎很少关注其思想哲学的相关问题。本文旨在论证辛弃疾的哲学思想乃是以陈亮为代表的事功派哲学一脉,并探讨事功派哲学对稼轩词艺术特质及词史地位所产生的深刻影响。%Chen Liang, the philosopher of Utilitarianism Ethics Thought, has a good relationship with Xin Qi-ji. So his philosophical thoughts certainly would have an influence on Xin Qiji. But in the past, on the study of Xin Qi-ji, we can seldom found researches concerning his thought of philosophy. This dissertation is aimed to argue that Xin's philosophical thoughts is a brunch of Chen’s Utilitarianism Ethics Thought and the latter had great influence on Jiaxuan Ci-Poems, including its artistic particularities and the status in Ci-poetry history.

  11. Translational selection in human: More pronounced in housekeeping genes

    KAUST Repository

    Ma, Lina

    2014-07-10

    Background: Translational selection is a ubiquitous and significant mechanism to regulate protein expression in prokaryotes and unicellular eukaryotes. Recent evidence has shown that translational selection is weakly operative in highly expressed genes in human and other vertebrates. However, it remains unclear whether translational selection acts differentially on human genes depending on their expression patterns.Results: Here we report that human housekeeping (HK) genes that are strictly defined as genes that are expressed ubiquitously and consistently in most or all tissues, are under stronger translational selection.Conclusions: These observations clearly show that translational selection is also closely associated with expression pattern. Our results suggest that human HK genes are more efficiently and/or accurately translated into proteins, which will inevitably open up a new understanding of HK genes and the regulation of gene expression.Reviewers: This article was reviewed by Yuan Yuan, Baylor College of Medicine; Han Liang, University of Texas MD Anderson Cancer Center (nominated by Dr Laura Landweber) Eugene Koonin, NCBI, NLM, NIH, United States of America Sandor Pongor, International Centre for Genetic Engineering and biotechnology (ICGEB), Italy. © 2014 Ma et al.; licensee BioMed Central Ltd.

  12. Tacrolimus in preventing transplant rejection in Chinese patients – optimizing use

    Directory of Open Access Journals (Sweden)

    Li CJ

    2015-01-01

    Full Text Available Chuan-Jiang Li,1,* Liang Li2,* 1Department of Surgery, Nanfang Hospital, 2Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, People’s Republic of China *The authors contributed equally to this work Abstract: Tacrolimus is a product of fermentation of Streptomyces, and belongs to the family of calcineurin inhibitors. It is a widely used immunosuppressive drug for preventing solid-organ transplant rejection. Compared to cyclosporine, tacrolimus has greater immunosuppressive potency and a lower incidence of side effects. It has been accepted as first-line treatment after liver and kidney transplantation. Tacrolimus has specific features in Chinese transplant patients; its in vivo pharmacokinetics, treatment regimen, dose and administration, and adverse-effect profile are influenced by multiple factors, such as genetics and the spectrum of primary diseases in the Chinese population. We reviewed the clinical experience of tacrolimus use in Chinese liver- and kidney-transplant patients, including the pharmacology of tacrolimus, the immunosuppressive effects of tacrolimus versus cyclosporine, effects of different factors on tacrolimus metabolism on Chinese patients, personalized medicine, clinical safety profile, and patient satisfaction and adherence. This article provides guidance for the rational and efficient use of tacrolimus in Chinese organ-transplant patients. Keywords: tacrolimus, liver transplantation, kidney transplant, Chinese, personalized medicine

  13. Visualization of Atmospheric Water Vapor Data for SAGE

    Science.gov (United States)

    Kung, Mou-Liang; Chu, W. P. (Technical Monitor)

    2000-01-01

    The goal of this project was to develop visualization tools to study the water vapor dynamics using the Stratospheric Aerosol and Gas Experiment 11 (SAGE 11) water vapor data. During the past years, we completed the development of a visualization tool called EZSAGE, and various Gridded Water Vapor plots, tools deployed on the web to provide users with new insight into the water vapor dynamics. Results and experiences from this project, including papers, tutorials and reviews were published on the main Web page. Additional publishing effort has been initiated to package EZSAGE software for CD production and distribution. There have been some major personnel changes since Fall, 1998. Dr. Mou-Liang Kung, a Professor of Computer Science assumed the PI position vacated by Dr. Waldo Rodriguez who was on leave. However, former PI, Dr. Rodriguez continued to serve as a research adviser to this project to assure smooth transition and project completion. Typically in each semester, five student research assistants were hired and trained. Weekly group meetings were held to discuss problems, progress, new research direction, and activity planning. Other small group meetings were also held regularly for different objectives of this project. All student research assistants were required to submit reports for conference submission.

  14. Carbon nanotube-incorporated collagen hydrogels improve cell alignment and the performance of cardiac constructs

    Directory of Open Access Journals (Sweden)

    Sun HY

    2017-04-01

    Full Text Available Hongyu Sun,* Jing Zhou,* Zhu Huang,* Linlin Qu,* Ning Lin,* Chengxiao Liang, Ruiwu Dai, Lijun Tang, Fuzhou Tian General Surgery Center, Chengdu Military General Hospital, Chengdu, China *These authors contributed equally to this work Abstract: Carbon nanotubes (CNTs provide an essential 2-D microenvironment for cardiomyocyte growth and function. However, it remains to be elucidated whether CNT nanostructures can promote cell–cell integrity and facilitate the formation of functional tissues in 3-D hydrogels. Here, single-walled CNTs were incorporated into collagen hydrogels to fabricate (CNT/Col hydrogels, which improved mechanical and electrical properties. The incorporation of CNTs (up to 1 wt% exhibited no toxicity to cardiomyocytes and enhanced cell adhesion and elongation. Through the use of immunohistochemical staining, transmission electron microscopy, and intracellular calcium-transient measurement, the incorporation of CNTs was found to improve cell alignment and assembly remarkably, which led to the formation of engineered cardiac tissues with stronger contraction potential. Importantly, cardiac tissues based on CNT/Col hydrogels were noted to have better functionality. Collectively, the incorporation of CNTs into the Col hydrogels improved cell alignment and the performance of cardiac constructs. Our study suggests that CNT/Col hydrogels offer a promising tissue scaffold for cardiac constructs, and might serve as injectable biomaterials to deliver cell or drug molecules for cardiac regeneration following myocardial infarction in the near future. Keywords: carbon nanotubes, collagen hydrogel, cardiac constructs, cell alignment, tissue functionality

  15. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system.

    Science.gov (United States)

    Ren, Huixia; Luo, Chuanming; Feng, Yanqing; Yao, Xiaoli; Shi, Zhe; Liang, Fengyin; Kang, Jing X; Wan, Jian-Bo; Pei, Zhong; Su, Huanxing

    2017-01-01

    Impairment of amyloid-β (Aβ) clearance leads to Aβ accumulation in the brain during the development of Alzheimer's disease (AD). Strategies that can restore or improve the clearance function hold great promise in delaying or preventing the onset of AD. Here, we show that n-3 polyunsaturated fatty acids (PUFAs), by use of fat-1 transgenic mice and oral administration of fish oil, significantly promote interstitial Aβ clearance from the brain and resist Aβ injury. Such beneficial effects were abolished in Aqp4-knockout mice, suggesting that the AQP4-dependent glymphatic system is actively involved in the promoting the effects of n-3 PUFAs on the clearance of extracellular Aβ. Imaging on clarified brain tissues clearly displayed that n-3 PUFAs markedly inhibit the activation of astrocytes and protect the AQP4 polarization in the affected brain region after Aβ injection. The results of the present study prove a novel mechanism by which n-3 PUFAs exert protective roles in reducing Aβ accumulation via mediating the glymphatic system function.-Ren, H., Luo, C., Feng, Y., Yao, X., Shi, Z., Liang, F., Kang, J. X., Wan, J.-B., Pei, Z., Su, H. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system. © FASEB.

  16. Sebaran Spasial Komunitas Lamun di Pulau Bone Batang Sulawesi Selatan

    Directory of Open Access Journals (Sweden)

    Dody Priosambodo

    2015-06-01

    Full Text Available Penelitian mengenai sebaran spasial komunitas lamun dilakukan di pulau Bone Batang, Sulawesi Selatan. Tujuan penelitian ini adalah untuk mengetahui pengaruh karakteristik habitat dan faktor lingkungan khususnya pada fauna yang hidup pada spesies lamun dan sebaran spasialnya. Data kepadatan lamun diperoleh dari 8 stasiun disekitar pulau. Komposisi spesies lamun pada kawasan terumbu karang diamati dengan metode Tarp. Melalui persamaan Bay-Curtis dan analisis n-MDS, hasil menunjukkan bahwa komposisi lamun dari stasiun yang ada pada pulau Bone Batang terdiri atas spesies yang sama dengan Indeks kesamaan lebih dari 75% kecuali pada stasiun 2 dan 3. Komposisi lamun dibagi dalam 3 kelompok. Analisis korespondensi menunjukkan bahwa sebaran spasial dari stasiun berbeda dan dipengaruhi oleh karakteristik habitat. Thalassia hemprichii mendominasi stasiun 1, 3, 7, 8 sementara Cymodea rotundata mendominasi stasiun 2, 5, 6. Spesies perintis contohnya Halodule uninervis dan Halophila ovalis mendominasi stasiun 3 dan 4. Spesies lamun terbesar Enhalus acoroides mendominasi stasiun 7 dan 8. Sebaran spasial dan komposisi spesies juga menunjukkan bahwa padang lamun di Bone Batang dalam tahap dewasa. Fauna yang hidup di padang lamun Bone Batang melimpah dan didominasi spesies liang. Dapat disimpulkan, bahwa campuran komunitas lamun dengan beragam spesies lamun dan dipengaruhi oleh karakteristik habitat dan fauna yang hidup di dalamnya.Kata kunci: Sebaran Spasial, Lamun, Asosiasi Fauna, Sulawesi Selatan

  17. Performance of cooling installation for cyclotron Decy-13

    International Nuclear Information System (INIS)

    Edi Trijono Budisantoso; Suprapto; Sutadi

    2015-01-01

    Has been calculated the cooling installation performance of Decy-13 cyclotron. The cooling installation is analysed based on the technical specifications of each cooling component to proof the results of the design and implementation of installations meet the cooling requirement. Analysis of loss of pressure and flow rate in the piping installation is done empirically using Hazen-Williams equation while the analysis of heat transfer processes in the cooling tower is done using the help of psychometric charts that available. Cooling component consists of a condenser and associated piping systems with cooling towers and equipped with a pump to push the circulation of cooling. The calculations show that the installation of the condenser cooler uses the cooling tower LiangChi LBC-30 with a booster pump Grundfos 4 kW NF30-36T powered 47kW able to transfer heat with the coolant flow rate 136 lpm, input to output coolant pressure difference 2.1atm and the cooling temperature difference 5 °C. Conclusion of the calculation is the technical specifications of cooling components and installation already meets the needs of the cooling expected. (author)

  18. Relations between stellar mass and electron temperature-based metallicity for star-forming galaxies in a wide mass range

    International Nuclear Information System (INIS)

    Shi Wei-Bin; Zhao Gang; Ruan Gui-Ping; Zhou Li; Liang Yan-Chun; Shao Xu; Liu Xiao-Wei; Hammer Francois; Flores Hector; Zhang Yong

    2014-01-01

    We select 947 star-forming galaxies from SDSS-DR7 with [O III]λ4363 emission lines detected at a signal-to-noise ratio larger than 5σ. Their electron temperatures and direct oxygen abundances are then determined. We compare the results from different methods. t 2 , the electron temperature in the low ionization region, estimated from t 3 , that in the high ionization region, is compared using three analysis relations between t 2 – t 3 . These show obvious differences, which result in some different ionic oxygen abundances. The results of t 3 , t 2 , O ++ /H + and O + /H + derived by using methods from IRAF and literature are also compared. The ionic abundances O ++ /H + are higher than O + /H + for most cases. The different oxygen abundances derived from T e and the strong-line ratios show a clear discrepancy, which is more obvious following increasing stellar mass and strong-line ratio R 23 . The sample of galaxies from SDSS with detected [O III]λ4363 have lower metallicites and higher star formation rates, so they may not be typical representatives of the whole population of galaxies. Adopting data objects from Andrews and Martini, Liang et al. and Lee et al. data, we derive new relations of stellar mass and metallicity for star-forming galaxies in a much wider stellar mass range: from 10 6 M ⊙ to 10 11 M ⊙ . (research papers)

  19. A polyethylenimine-modified carboxyl-poly(styrene/acrylamide copolymer nanosphere for co-delivering of CpG and TGF-β receptor I inhibitor with remarkable additive tumor regression effect against liver cancer in mice

    Directory of Open Access Journals (Sweden)

    Liang SY

    2016-12-01

    Full Text Available Shuyan Liang,* Jun Hu,* Yuanyuan Xie, Qing Zhou, Yanhong Zhu, Xiangliang Yang National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, People’s Republic of China *These authors contributed equally to this work Abstract: Cancer immunotherapy based on nanodelivery systems has shown potential for treatment of various malignancies, owing to the benefits of tumor targeting of nanoparticles. However, induction of a potent T-cell immune response against tumors still remains a challenge. In this study, polyethylenimine-modified carboxyl-styrene/acrylamide (PS copolymer nanospheres were developed as a delivery system of unmethylated cytosine-phosphate-guanine (CpG oligodeoxynucleotides and transforming growth factor-beta (TGF-β receptor I inhibitors for cancer immunotherapy. TGF-β receptor I inhibitors (LY2157299, LY were encapsulated to the PS via hydrophobic interaction, while CpG oligodeoxynucleotides were loaded onto the PS through electrostatic interaction. Compared to the control group, tumor inhibition in the PS-LY/CpG group was up to 99.7% without noticeable toxicity. The tumor regression may be attributed to T-cell activation and amplification in mouse models. The results highlight the additive effect of CpG and TGF-β receptor I inhibitors co-delivered in cancer immunotherapy. Keywords: CpG, TGF-β receptor I inhibitor, Pst-AAm copolymer nanosphere, immunotherapy

  20. Effects of Arthro-7® in relieving symptoms of osteoarthritis with mild to moderate arthralgia [Corrigendum

    Directory of Open Access Journals (Sweden)

    Xie Q

    2013-05-01

    Full Text Available  Xie Q, Zhou T, Yen L, Shariff M, Nguyen T, Kami K, Gu P, Liang L, Rao J, Shi R. Nutrition and Dietary Supplements. 2013;5:1–6.On page 2, under the Materials section, the 1st paragraph should read "The Arthro-7 and placebo capsules were provided by Robinson Pharma (Orange County, CA, USA. The Arthro-7 was in the form of capsules containing vitamin C, collagen (from chicken cetyl myristoleate (CMO, lipase, methylsulfonylmethane (MSM, curcumin, and bromelain (Table 1. The main ingredient of the placebo capsule was corn powder. In addition, there were gelatin, glycerin, purified water and titanium dioxide, and artificial food coloring."On page 4, under the Discussion section, 2nd paragraph, the 2nd and 3rd sentences should read "Collagen is the main component of articular cartilage and the principal substance responsible for maintaining the physical, chemical, and mechanical properties of articular cartilage. The collagen in Arthro-7 is extracted from chicken, which has previously been shown to suppress collagen-induced arthritis.18"Read the original article  

  1. Bounds and inequalities relating h-index, g-index, e-index and generalized impact factor: an improvement over existing models.

    Science.gov (United States)

    Abbas, Ash Mohammad

    2012-01-01

    In this paper, we describe some bounds and inequalities relating h-index, g-index, e-index, and generalized impact factor. We derive the bounds and inequalities relating these indexing parameters from their basic definitions and without assuming any continuous model to be followed by any of them. We verify the theorems using citation data for five Price Medalists. We observe that the lower bound for h-index given by Theorem 2, [formula: see text], g ≥ 1, comes out to be more accurate as compared to Schubert-Glanzel relation h is proportional to C(2/3)P(-1/3) for a proportionality constant of 1, where C is the number of citations and P is the number of papers referenced. Also, the values of h-index obtained using Theorem 2 outperform those obtained using Egghe-Liang-Rousseau power law model for the given citation data of Price Medalists. Further, we computed the values of upper bound on g-index given by Theorem 3, g ≤ (h + e), where e denotes the value of e-index. We observe that the upper bound on g-index given by Theorem 3 is reasonably tight for the given citation record of Price Medalists.

  2. Immunocompromised and immunocompetent mouse models for head and neck squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Lei ZG

    2016-01-01

    Full Text Available Zhen-ge Lei,1,* Xiao-hua Ren,2,* Sha-sha Wang,3 Xin-hua Liang,3,4 Ya-ling Tang3,5 1Department of Oral and Maxillofacial Surgery, Stomatological Hospital Affiliated to Nanchang University, Nanchang, Jiangxi, 2Department of Stomatology, Sichuan Medical Science Academy and Sichuan Provincial People’s Hospital, 3State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, 4Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, 5Department of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People’s Republic of China *These authors contributed equally to this work Abstract: Mouse models can closely mimic human oral squamous epithelial carcinogenesis, greatly expand the in vivo research possibilities, and play a critical role in the development of diagnosis, monitoring, and treatment of head and neck squamous cell carcinoma. With the development of the recent research on the contribution of immunity/inflammation to cancer initiation and progression, mouse models have been divided into two categories, namely, immunocompromised and immunocompetent mouse models. And thus, this paper will review these two kinds of models applied in head and neck squamous cell carcinoma to provide a platform to understand the complicated histological, molecular, and genetic changes of oral squamous epithelial tumorigenesis. Keywords: head and neck squamous cell carcinoma, HNSCC, mouse models, immunocompromised models, immunocompetent models, transgenic models

  3. Nematodes, exotic earthworms and nitrogen addition: interactions between global change factors lead to cancellation effects.

    Science.gov (United States)

    De Long, Jonathan R

    2017-07-01

    Photos from the experiment described in Shao et al. (): (a) the endogeic (i.e. earthworms that typically live in the soil, burrowing horizontally to acquire nutrients) earthworm Pontoscolex corethrurus that was added to the plots; (b) P. corethrurus in a quiescence state in response to drought; (c) set-up of the control plots (i.e. no earthworms, ambient nitrogen) used in this experiment. [Colour figure can be viewed at wileyonlinelibrary.com] In Focus: Shao, Y., Zhang, W., Eisenhauer, N., Liu, T., Xiong, Y., Liang, C. & Fu, S. (2017) Nitrogen deposition cancels out exotic earthworm effects on plant-feeding nematode communities. Journal of Animal Ecology, 86, 708-717. In this issue of Journal of Animal Ecology, Shao et al. () explored how N addition and exotic earthworms interacted to impact on the plant-feeding nematode community. They demonstrate that exotic earthworm presence alone increased the abundance of less harmful plant-feeding nematodes and decreased the abundance of the more harmful plant-feeding nematodes. However, in plots receiving both exotic earthworms and N addition, such earthworm effects on the nematode community were negated. These findings pull focus on the need to simultaneously consider multiple global change factors (e.g. exotic species invasions and N deposition) when making predictions about how such factors might affect above- and below-ground interactions and thereby alter ecosystem function. © 2017 The Author. Journal of Animal Ecology © 2017 British Ecological Society.

  4. A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection

    Directory of Open Access Journals (Sweden)

    Wang Q

    2016-03-01

    Full Text Available Qingjun Wang,1,2,* Tao Sun,3,* Yunfeng Cao,1,2,4,5 Peng Gao,2,4,6 Jun Dong,2,4 Yanhua Fang,2 Zhongze Fang,2 Xiaoyu Sun,2 Zhitu Zhu1,2 1Oncology Department 2, The First Affiliated Hospital of Liaoning Medical University, 2Personalized Treatment and Diagnosis Research Center, The First Affiliated Hospital of Liaoning Medical University and Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Jinzhou, 3Department of Internal Medicine 1, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Insititute, Shenyang, 4CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 5Key Laboratory of Contraceptives and Devices Research (NPFPC, Shanghai Engineer and Technology Research Center of Reproductive Health Drug and Devices, Shanghai Institute of Planned Parenthood Research, Shanghai, 6Clinical Laboratory, Dalian Sixth People’s Hospital, Dalian, People’s Republic of China *These authors contributed equally to this work Objective: Breast cancer (BC is still a lethal threat to women worldwide. An accurate screening and diagnosis strategy performed in an easy-to-operate manner is highly warranted in clinical perspective. Besides the routinely focused protein markers, blood is full of small molecular metabolites with diverse structures and properties. This study aimed to screen metabolite markers with BC diagnosis potentials.Methods: A dried blood spot-based direct infusion mass spectrometry (MS metabolomic analysis was conducted for BC and non-BC differentiation. The targeted analytes included 23 amino acids and 26 acylcarnitines.Results: Multivariate analysis screened out 21 BC-related metabolites in the blood. Regression analysis generated a diagnosis model consisting of parameters Pip, Asn, Pro, C14:1/C16, Phe/Tyr, and Gly/Ala. Tested with another set of BC and non-BC samples, this model showed a sensitivity of 92.2% and a specificity

  5. Probiotics Supplementation Therapy for Pathological Neonatal Jaundice: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Zhe Chen

    2017-06-01

    Full Text Available Background: Neonatal jaundice is a relatively prevalent disease and affects approximately 2.4–15% newborns. Probiotics supplementation therapy could assist to improve the recovery of neonatal jaundice, through enhancing immunity mainly by regulating bacterial colonies. However, there is limited evidence regarding the effect of probiotics on bilirubin level in neonates. Therefore, this study aims at systematically evaluating the efficacy and safety of probiotics supplement therapy for pathological neonatal jaundice.Methods: Databases including PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI, Wan Fang Database (Wan Fang, Chinese Biomedical Literature Database (CBM, VIP Database for Chinese Technical Periodicals (VIP were searched and the deadline is December 2016. Randomized controlled trials (RCTs of probiotics supplementation for pathological neonatal jaundice in publications were extracted by two reviewers. The cochrane tool was applied to assessing the risk of bias of the trials. The extracted information of RCTs should include efficacy rate, serum total bilirubin level, time of jaundice fading, duration of phototherapy, duration of hospitalization, adverse reactions. The main outcomes of the trials were analyzed by Review Manager 5.3 software. The relative risks (RR or mean difference (MD with a 95% confidence interval (CI was used to measure the effect.Results: 13 RCTs involving 1067 neonatal with jaundice were included in the meta-analysis. Probiotics supplementation treatment showed efficacy [RR: 1.19, 95% CI (1.12, 1.26, P < 0.00001] in neonatal jaundice. It not only decreased the total serum bilirubin level after 3day [MD: −18.05, 95% CI (−25.51, −10.58, P < 0.00001], 5day [MD: -23.49, 95% CI (−32.80, −14.18, P < 0.00001], 7day [MD: −33.01, 95% CI (−37.31, −28.70, P < 0.00001] treatment, but also decreased time of jaundice fading [MD: −1.91, 95% CI (−2.06, −1.75, P < 0.00001], as

  6. Cognitive Style and Mobile E-Learning in Emergent Otorhinolaryngology-Head and Neck Surgery Disorders for Millennial Undergraduate Medical Students: Randomized Controlled Trial.

    Science.gov (United States)

    Lee, Li-Ang; Chao, Yi-Ping; Huang, Chung-Guei; Fang, Ji-Tseng; Wang, Shu-Ling; Chuang, Cheng-Keng; Kang, Chung-Jan; Hsin, Li-Jen; Lin, Wan-Ni; Fang, Tuan-Jen; Li, Hsueh-Yu

    2018-02-13

    different cognitive styles. Clinicaltrials.gov NCT02971735; https://clinicaltrials.gov/ct2/show/NCT02971735 (Archived by WebCite at http://www.webcitation.org/6waoOpCEV). ©Li-Ang Lee, Yi-Ping Chao, Chung-Guei Huang, Ji-Tseng Fang, Shu-Ling Wang, Cheng-Keng Chuang, Chung-Jan Kang, Li-Jen Hsin, Wan-Ni Lin, Tuan-Jen Fang, Hsueh-Yu Li. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 13.02.2018.

  7. Impact of parental cancer on IQ, stress resilience, and physical fitness in young men

    Directory of Open Access Journals (Sweden)

    Chen R

    2018-05-01

    Full Text Available Ruoqing Chen,1 Katja Fall,1,2 Kamila Czene,1 Beatrice Kennedy,2 Unnur Valdimarsdóttir,1,3,4 Fang Fang1 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden; 3Centre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavík, Iceland; 4Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA Background: A parental cancer diagnosis is a stressful life event, potentially leading to increased risks of mental and physical problems among children. This study aimed to investigate the associations of parental cancer with IQ, stress resilience, and physical fitness of the affected men during early adulthood. Materials and methods: In this Swedish population-based study, we included 465,249 men born during 1973–1983 who underwent the military conscription examination around the age of 18 years. We identified cancer diagnoses among the parents of these men from the Cancer Register. IQ, stress resilience, and physical fitness of the men were assessed at the time of conscription and categorized into three levels: low, moderate, and high (reference category. We used multinomial logistic regression to assess the studied associations. Results: Overall, parental cancer was associated with higher risks of low stress resilience (relative risk ratio [RRR]: 1.09 [95% confidence interval (CI 1.04–1.15] and low physical fitness (RRR: 1.12 [95% CI 1.05–1.19]. Stronger associations were observed for parental cancer with a poor expected prognosis (low stress resilience: RRR: 1.59 [95% CI 1.31–1.94]; low physical fitness: RRR: 1.45 [95% CI 1.14–1.85] and for parental death after cancer diagnosis (low stress resilience: RRR: 1.29 [95% CI 1.16–1.43]; low physical fitness: RRR: 1.40 [95% CI 1.23–1.59]. Although there was no overall association between parental

  8. Incidence and clinical characteristics of unexpected uterine sarcoma after hysterectomy and myomectomy for uterine fibroids: a retrospective study of 10,248 cases

    Directory of Open Access Journals (Sweden)

    Zhao WC

    2015-10-01

    Full Text Available Wan-Cheng Zhao,1 Fang-Fang Bi,1 Da Li,2 Qing Yang11Department of Obstetrics and Gynecology, 2Center of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of ChinaBackground: Uterine fibroids often require a hysterectomy or myomectomy via laparotomy or laparoscopy. Morcellation is often necessary to perform a laparoscopic surgery. The objective of this study is to determine the incidence of unexpected uterine sarcomas (UUSs after hysterectomy and myomectomy for uterine fibroids and to reduce the occurrence and avoid the morcellation of UUSs by analyzing their characteristics.Methods: Women who had a hysterectomy or myomectomy for uterine fibroids in Shengjing Hospital of China Medical University between November 2008 and November 2014 were selected for the study, and their clinical characteristics were analyzed.Results: During the period, 48 UUSs were found in 10,248 cases, and the overall incidence was 0.47%. There was no statistical difference (P=0.449 regarding the incidence (0.50% vs 0.33% between 42 UUSs in 8,456 cases undergoing laparotomy and six UUSs in 1,792 cases undergoing laparoscopy. Most of the UUSs were stage I (89.58%, which occurred more commonly (56.25% in women aged 40–49. Abnormal uterine bleeding (39.58% was the main clinical manifestation. Rapidly growing pelvic masses (12.5%, rich blood flow signals (18.75%, and degeneration of uterine fibroids (18.75% prompted by ultrasonography may suggest the possibility of UUSs. The margins of most UUSs (93.75% were regular, which may cause UUSs to be misdiagnosed as uterine fibroids. Fifteen cases underwent magnetic resonance imaging examinations. Approximately 73.33% showed heterogeneous and hypointense signal intensity on T1-weighted images, and 80% showed intermediate-to-high signal intensity on T2-weighted images, with necrosis and hemorrhage in 40% of cases. After contrast administration, 80% presented early heterogeneous

  9. Acupuncture for chronic prostatitis: A systematic review and meta-analysis protocol.

    Science.gov (United States)

    Peng, Tianzhong; Cheng, Ying; Jin, Yuhao; Xu, Na; Guo, Taipin

    2018-04-01

    Chronic prostatitis (CP) is a prevalent genitourinary condition. Considering its safety profile, acupuncture can be an option treating CP symptoms. The aim of this review is to undertake a systematic review to estimate the effectiveness and safety of acupuncture on CP. We will search all randomized controlled trials for CP in August 2018 in the databases of MEDLINE, Cochrane Library, Web of Science, EMBASE, Springer, WHO International Clinical Trials Registry Platform (ICTRP), China National Knowledge Infrastructure (CNKI), Wan fang, Chinese Biomedical Literature Database (CBM), PsycInfo, Chinese Scientific Journal Database (VIP), and other available resources. Languages are limited as English and Chinese. Search terms used are will "acupuncture," and "chronic prostatitis," "non-bacterial prostatitis," "abacterial prostatitis." And duplicates will be screened. The primary outcomes consisted of improvement rate and pain relief evaluated by The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) index. Secondary outcomes include the recurrence rate and side effects, such as pneumothorax, discomforts, and infection. This study will demonstrate an evidence-based review of acupuncture for chronic prostatitis. The study will provide clear evidence to assess the effectiveness and side effects of acupuncture for chronic prostatitis. There is no requirement of ethical approval and it will be in print or disseminated by electronic copies. CRD42018088834.

  10. Effect of Sling Exercise Training on Balance in Patients with Stroke: A Meta-Analysis.

    Science.gov (United States)

    Chen, Lianghua; Chen, Junqi; Peng, Qiyuan; Chen, Jingjie; Zou, Yucong; Liu, Gang

    2016-01-01

    This study aims to evaluate the effect of sling exercise training (SET) on balance in patients with stroke. PubMed, Cochrane Library, Ovid LWW, CBM, CNKI, WanFang, and VIP databases were searched for randomized controlled trials of the effect of SET on balance in patients with stroke. The study design and participants were subjected to metrological analysis. Berg balance Scale (BBS), Barthel index score (BI), and Fugl-Meyer Assessment (FMA) were used as independent parameters for evaluating balance function, activities of daily living(ADL) and motor function after stroke respectively, and were subjected to meta-analysis by RevMan5.3 software. Nine studies with 460 participants were analyzed. Results of meta-analysis showed that the SET treatment combined with conventional rehabilitation was superior to conventional rehabilitation treatments, with increased degrees of BBS (WMD = 3.81, 95% CI [0.15, 7.48], P = 0.04), BI (WMD = 12.98, 95% CI [8.39, 17.56], P risk of bias. Therefore, more multi-center and large-sampled randomized controlled trials are needed to confirm its clinical applications.

  11. Verifikasi Dua Varian Protokol Ad hoc On demand Distance Vector dengan UPPAAL

    Directory of Open Access Journals (Sweden)

    Ika Oktavia Suzanti

    2015-01-01

    Abstract  MANET is a group of wireless mobile that connected one to each other without fixed infrastructure so topology could change at anytime. MANET routing protocol has two models which are reactive routing protocol that built routing table only when needed and proactive routing protocol that maintain routing table periodically. General property which had to be satisfied by ad-hoc network protocol are route discovery, packet delivery and loop freedom. AODV is a reactive protocol in MANET that has time standard to determine how long a route is valid to be used (route validity so route discovery and packet delivery property should be satisfied in a specifically certain time. Protocol verification process done by modeling protocol specification using technique, tool and mathematic language. In this research protocol modeled using timed automata which is a modeling language that could be used to model a time dependent system in each process. Verification using timed automata can automatically done by UPPAAL tool model checker. Protocol which will be verified are AODV Break Avoidance by Ali Khosrozadeh et al. and AODV Reliable Delivery by Liu Jian and Fang-Min. Result of this protocol verification prove that AODV BA could satisfied route discovery property and AODV Reliable Delivery could satisfied packet delivery property within their specification time.   Keywords—Protocol Verification, Timed Automata, AODV, UPPAAL

  12. Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria: A meta-analysis and trial sequential analysis

    Science.gov (United States)

    Sun, Fengmei; Zhang, Juan; Pu, Yuepu

    2017-10-01

    This study is designed to perform a meta-analysis and trial sequential analysis (TSA) to investigate whether people with G6PD deficiency suffered less malarial infection. We searched from PubMed, Science Direct, Springer Link, CNKI, and Wan Fang databases for case-control study, cohort study or cross section study until April 2017. TSA was used to determine the state of evidence and calculate the required sample size. Eight case-control studies and five cross-sectional studies (30,683participants) were included in this meta-analysis. Compared with normal control group, we found significant protection from severe malaria (OR 0.644, 95% CI [0.493-0.842]; P=0.001) among people with decreasing G6PD activity. People with variations of G6PD gene at nucleotide 202(G6PD A-) were also found to be associated with resistance on severe malaria pooled (OR 0.851, 95% CI [0.779-0.930]; P =0.0001). Sex-stratified test suggested that protection of severe malaria is conferred to both G6PD A-males and heterozygous females (with a single copy of the variant). In conclusion, our study found a significant protection from severe malaria among G6PD deficient people compared to the

  13. Acupuncture for treating sciatica: a systematic review protocol

    Science.gov (United States)

    Qin, Zongshi; Liu, Xiaoxu; Yao, Qin; Zhai, Yanbing; Liu, Zhishun

    2015-01-01

    Introduction This systematic review aims to assess the effectiveness and safety of acupuncture for treating sciatica. Methods The following nine databases will be searched from their inception to 30 October 2014: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), the Chinese Biomedical Literature Database (CBM), the Chinese Medical Current Content (CMCC), the Chinese Scientific Journal Database (VIP database), the Wan-Fang Database, the China National Knowledge Infrastructure (CNKI) and Citation Information by National Institute of Informatics (CiNii). Randomised controlled trials (RCTs) of acupuncture for sciatica in English, Chinese or Japanese without restriction of publication status will be included. Two researchers will independently undertake study selection, extraction of data and assessment of study quality. Meta-analysis will be conducted after screening of studies. Data will be analysed using risk ratio for dichotomous data, and standardised mean difference or weighted mean difference for continuous data. Dissemination This systematic review will be disseminated electronically through a peer-reviewed publication or conference presentations. Trial registration number PROSPERO CRD42014015001. PMID:25922105

  14. ALK-positive anaplastic large cell lymphoma with soft tissue involvement in a young woman

    Directory of Open Access Journals (Sweden)

    Gao KH

    2016-07-01

    Full Text Available Kehai Gao, Hongtao Li, Caihong Huang, Huazhuang Li, Jun Fang, Chen Tian Department of Orthopaedics, Yidu Central Hospital, Shandong, People’s Republic of China Introduction: Anaplastic large cell lymphoma (ALCL is a type of non-Hodgkin lymphoma that has strong expression of CD30. ALCL can sometimes involve the bone marrow, and in advanced stages, it can produce destructive extranodal lesions. But anaplastic large cell lymphoma kinase (ALK+ ALCL with soft tissue involvement is very rare.Case report: A 35-year-old woman presented with waist pain for over 1 month. The biopsy of soft tissue lesions showed that these cells were positive for ALK-1, CD30, TIA-1, GranzymeB, CD4, CD8, and Ki67 (90%+ and negative for CD3, CD5, CD20, CD10, cytokeratin (CK, TdT, HMB-45, epithelial membrane antigen (EMA, and pan-CK, which identified ALCL. After six cycles of Hyper-CVAD/MA regimen, she achieved partial remission. Three months later, she died due to disease progression.Conclusion: This case illustrates the unusual presentation of ALCL in soft tissue with a bad response to chemotherapy. Because of the tendency for rapid progression, ALCL in young adults with extranodal lesions are often treated with high-grade chemotherapy, such as Hyper-CVAD/MA. Keywords: anaplastic large cell lymphoma, ALK+, soft tissue involvement, Hyper-CVAD/MA

  15. Charge Transfer Processes in Collisions of Si4+ Ions with He Atoms at Intermediate Energies

    Science.gov (United States)

    Suzuki, R.; Watanabe, A.; Sato, H.; Gu, J. P.; Hirsch, G.; Buenker, R. J.; Kimura, M.; Stancil, P. C.

    Charge transfer in collisions of Si4+ ions with He atoms below 100 keV/u is studied by using a molecular orbital representation within both the semiclassical and quantal representations. Single transfer reaction Si4++He →Si3++He+ has been studied by a number of theoretical investigations. In addition to the reaction (1), the first semiclassical MOCC calculations are performed for the double transfer channel Si4++HE→Si2++He2+ Nine molecular states that connect both with single and double electron transfer processes are considered in the present model. Electronic states and corresponding couplings are determined by the multireference single- and double- excitation configuration interaction method. The present cross sections tie well with the earlier calculations of Stancil et al., Phys. Rev. A 55, 1064 (1997) at lower energies, but show a rather different magnitude from those of Bacchus-Montabonel and Ceyzeriat, Phys. Rev. A 58, 1162 (1998). The present rate constant is found to be significantly different from the experimental finding of Fang and Kwong, Phys. Rev. A 59, 342 (1996) at 4,600 K, and hence does not support the experiment.

  16. Charge transfer processes in collisions of Si{sup 4+} ions with He atoms at intermediate energies

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, R. [Hitotsubashi Univ., Tokyo (Japan). Computer Center; Watanabe, A. [Dept. of Information Sciences, Ochanomizu Univ., Tokyo (Japan); Sato, H. [Graduate School of Humanities and Sciences, Ochanomizu Univ., Tokyo (Japan); Gu, J.P.; Hirsch, G.; Buenker, R.J. [Wuppertal Univ. (Gesamthochschule) (Germany). Lehrgebiet Theoretische Chemie; Kimura, M. [Graduate School of Science and Engineering, Yamaguchi Univ., Ube (Japan); Stancil, P.C. [Georgia Univ., Athens, GA (United States). Dept. of Physics

    2001-07-01

    Charge transfer in collisions of Si{sup 4+} ions with He atoms below 100 keV/u is studied by using a molecular orbital representation within both the semiclassical and quantal representations. Single transfer reaction Si{sup 4+} + He {yields} Si{sup 3+} + He{sup +} has been studied by a number of theoretical investigations. In addition to the reaction (1), the first semiclassical MOCC calculations are performed for the double transfer channel Si{sup 4+} + He {yields} Si{sup 2+} + He{sup 2+}. Nine molecular states that connect both with single and double electron transfer processes are considered in the present model. Electronic states and corresponding couplings are determined by the multireference single- and double- excitation configuration interaction method. The present cross sections tie well with the earlier calculations of Stancil et al., (1997) at lower energies, but show a rather different magnitude from those of Bacchus-Montabonel and Ceyzeriat, (1998). The present rate constant is found to be significantly different from the experimental finding of Fang and Kwong, (1996) at 4,600 K, and hence does not support the experiment. (orig.)

  17. Efficacy and safety of prucalopride for chronic constipation: A meta-analysis

    Directory of Open Access Journals (Sweden)

    Hui-jun TANG

    2014-08-01

    Full Text Available Objective To evaluate the efficacy and safety of prucalopride in the treatment of chronic constipation (CC. Methods Articles regarding treatment of constipation were retrieved from PubMed, EMBASE, Web of Science, The Cochrane Central Register of Controlled Trials, Chinese Journals Full-text Database (CNKI, China National Knowledge Infrastructure, Wan Fang Digital Journal Full-text Database, and Database for Chinese Technical Periodical (VIP to collect clinical randomized controlled trials for CC treated by prucalopride. Meta analysis was performed by using Review Manager 5.0. Results A total of eleven randomized controlled trials including 3278 patients met the inclusion criteria, and ten of them were analyzed to compare the effect of prucalopride with placebo, and another group of articles were analyzed to compare the effect or prucalopride with that of PEG 3350+electrolytes. Mete-analysis showed that the efficacy rate was significantly higher in prucalopride group (29.2% than in the placebo group (12.6%, RR=2.37, 95% CI 2.02-2.79, P0.05. Conclusion Prucalopride is effective in the treatment of CC, with relatively milder and lower incidence of adverse reaction, and it could be a new choice for the treatment of CC. DOI: 10.11855/j.issn.0577-7402.2014.06.10

  18. ON THE OBSERVATION AND SIMULATION OF SOLAR CORONAL TWIN JETS

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Jiajia; Wang, Yuming; Zhang, Quanhao [CAS Key Laboratory of Geospace Environment, School of Earth and Space Sciences, University of Science and Technology of China, NO. 96, Jinzhai Road, Hefei, Anhui 230026 (China); Fang, Fang [Laboratory for Atmospheric and Space Physics, University of Colorado at Boulder, 1234 Innovation Drive, Boulder, CO 80303 (United States); McIntosh, Scott W.; Fan, Yuhong [High Altitude Observatory, National Center for Atmospheric Research, P.O. Box 3000, Boulder, CO 80307 (United States)

    2016-02-01

    We present the first observation, analysis, and modeling of solar coronal twin jets, which occurred after a preceding jet. Detailed analysis on the kinetics of the preceding jet reveals its blowout-jet nature, which resembles the one studied in Liu et al. However, the erupting process and kinetics of the twin jets appear to be different from the preceding one. Lacking detailed information on the magnetic fields in the twin jet region, we instead use a numerical simulation using a three-dimensional (3D) MHD model as described in Fang et al., and find that in the simulation a pair of twin jets form due to reconnection between the ambient open fields and a highly twisted sigmoidal magnetic flux, which is the outcome of the further evolution of the magnetic fields following the preceding blowout jet. Based on the similarity between the synthesized and observed emission, we propose this mechanism as a possible explanation for the observed twin jets. Combining our observation and simulation, we suggest that with continuous energy transport from the subsurface convection zone into the corona, solar coronal twin jets could be generated in the same fashion addressed above.

  19. The role of deep brain stimulation in Parkinson’s disease: an overview and update on new developments

    Directory of Open Access Journals (Sweden)

    Fang JY

    2017-03-01

    Full Text Available John Y Fang, Christopher Tolleson Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA Abstract: Parkinson’s disease (PD is a progressive neurodegenerative disorder characterized by the loss of neuronal dopamine production in the brain. Oral therapies primarily augment the dopaminergic pathway. As the disease progresses, more continuous delivery of therapy is commonly needed. Deep brain stimulation (DBS has become an effective therapy option for several different neurologic and psychiatric conditions, including PD. It currently has US Food and Drug Administration approval for PD and essential tremor, as well as a humanitarian device exception for dystonia and obsessive-compulsive disorder. For PD treatment, it is currently approved specifically for those patients suffering from complications of pharmacotherapy, including motor fluctuations or dyskinesias, and a disease process of at least 4 years of duration. Studies have demonstrated superiority of DBS and medical management compared to medical management alone in selected PD patients. Optimal patient selection criteria, choice of target, and programming methods for PD and the other indications for DBS are important topics that continue to be explored and remain works in progress. In addition, new hardware options, such as different types of leads, and different software options have recently become available, increasing the potential for greater efficacy and/or reduced side effects. This review gives an overview of therapeutic management in PD, specifically highlighting DBS and some of the recent changes with surgical therapy. Keywords: Parkinson’s disease, deep brain stimulation, functional neurosurgery 

  20. The development and impact of primary health care in China from 1949 to 2015: A focused review.

    Science.gov (United States)

    Li, Huazhang; Liu, Kun; Gu, Jianjun; Zhang, Yimin; Qiao, Yun; Sun, Xiaoming

    2017-07-01

    High-quality primary health care (PHC) services are associated with better health outcomes and positive health equity. Providing PHC services to all inhabitants is one of the Chinese government's health care objectives. However, an imbalance between people's increasing health needs and effective health service utilization exists in China. The objective of this review is to identify evidence for PHC development in China and to summarize the challenges as a reference for the future improvement of China's PHC system. Literature searches related to China's PHC were performed in PubMed, Web of Science, China National Knowledge Infrastructure, and Wan-fang databases. Related data were collected from the China Statistical Yearbook on Health and Family Planning 2003-2016, the China National Health Accounts Report 2015, and An Analysis Report of National Health Services Survey in China, 2013. The PHC network and the population's health have improved in China in recent years, with general practitioners as "gatekeepers" who have gradually taken the initiative to offer health services to residents. The limitation of input and shortages of resources and skilled health care providers may restrict the sustainable development of China's PHC system. Therefore, policy support from the government is necessary. Copyright © 2017 John Wiley & Sons, Ltd.