Sample records for leslie marmon silko

  1. Domestic Resistance: Gardening, Mothering, and Storytelling in Leslie Marmon Silko's "Gardens in the Dunes" (United States)

    Li, Stephanie


    Leslie Marmon Silko began her most recent work, "Gardens in the Dunes" (1999), intending to write a novel that would not be political. Following the publication of "Almanac of the Dead" (1992), which was simultaneously hailed as one of the most important books of the twentieth century and condemned for its angry self-righteousness, Silko…

  2. Leslie Marmon Silko and Simon J. Ortiz: Pathways to the Tradition

    Directory of Open Access Journals (Sweden)

    Dave Henderson


    Full Text Available Both Leslie Marmon Silko and Simon J. Ortiz have retold the story of a 1952 murder by two Pueblo brothers, a story that both writers first heard during their childhood years as it quickly became part of the local Native American traditional corpus. Both Silko and Ortiz are self-consciously indebted to the Native American storytelling tradition, particularly with respect to its malleability in the face of change, a fluidity that operates in tension with the preservation of certain fundamental religious and philosophical constants. Accordingly, Silko and Ortiz see their stories as providing pathways to the tradition, molding, reforming, and contributing to it without departing from it. Content, tone, style, and purpose are analyzed to reveal the variants in their redactions.

  3. The Dissolution of the Mexican-American Border and Redefinition of Chicano/a /Mexican Identity in Leslie Marmon Silko's Almanac of the Dead

    DEFF Research Database (Denmark)

    Harding, David


    In Leslie Marmon Silko's Almanac of the Dead, notions of Mexican identity are deconstructed. This article analyzes how Silko, through a variety of characters and sub-plotlines, brings to the surface hidden tensions in the contsruction of Mexican identity through the melding of the sangre limpia...

  4. From Delirium to Coherence: Shamanism and Medicine Plants in Silko's "Ceremony" (United States)

    Weso, Thomas F.


    A nondescript rock shelter in Texas provides the evidence for shamanism in Leslie Marmon Silko's novel, "Ceremony". There, archaeologists found identifiable images of antlered human figures and entheogenic plant substances, which are medicinal plants, associated with shamanistic practices.

  5. Special Problems in Teaching Leslie Marmon Silko's "Ceremony." (United States)

    Allen, Paula Gunn


    A professor of American Indian literature describes the ethical dilemma she faces when teaching "Ceremony," a novel built around spiritual beliefs and activities at Laguna Pueblo. Her pedagogical duty to provide students with the most complete coherent information possible conflicts directly with respect for the secrecy surrounding…

  6. Leslie Marmon Silko’s “Lullaby”: The Power of Resistance and Healing Force to Cultural and Spiritual Genocide


    Barrios Herrero, Olga


    [ES] Este ensayo muestra como el relato “Lullaby” de Leslie M. Silko despliega varios niveles de resistencia en defensa de la historia, tradición oral y mujeres nativoamericanas. La estructura circular narrativa de la historia es utilizada por Silko para reafirmar y recuperar la tradición oral de los Lagunas nativoamericanos. Y, al alegir a Ayah como el personal principal, una esposa y madre luchadora, la autora reclama laa tradición matriarcal de la comunidad nativoamericana en contraposició...

  7. Momaday, Welch, and Silko: Expressing the Feminine Principle through Male Alienation. (United States)

    Antell, Judith A.


    Examines common themes in three Native American novels by N. Scott Momaday, James Welch, and Leslie Silko: the power of Indian women's femaleness, and reintegration of the alienated male protagonist through ancient rituals that awaken the realization of the feminine principle within himself. (SV)

  8. Novel Choices, Pun Intended (United States)

    Shanley, Roger W.


    In this article, the author explains why he considers "Animal Dreams" by Barbara Kingsolver, "Ceremony" by Leslie Marmon Silko, and "The Joy Luck Club" by Amy Tan as the most desirable books for students. He cites that several questions guide him in selecting these books. These questions include the following: (1) Why recommend certain texts to…

  9. Honoring Leslie A. Geddes - farewell ... (United States)

    Valentinuzzi, Max E


    Honor thy father and thy mother, say the Holy Scriptures1, for they at least gave thee this biological life, but honor thy teachers, too, for they gave thee knowledge and example.Leslie Alexander Geddes took off on a long, long trip, Sunday October 25, 2009, leaving his body for medical and research use. The departing station was West Lafayette, Indiana, where he set foot in 1974, at Purdue University, stamping there a unique deep imprint, similar and probably more profound than the one left at Baylor College of Medicine (BCM), Houston, Texas, in the period 1955-1974. Memories came back as a flood the minute after a message broke the news to me: When I first met him visiting the Department of Physiology at BCM back in 1962, my first Classical Physiology with Modern Instrumentation Summer Course ... The versatile Physiograph was the main equipment, an electronic-mechanical three or four channel recorder that could pick up a variety of physiological variables. Les and his collaborators had introduced also the impedance pneumograph, which was a simplified version of previous developments made by others. It became a ubiquitous unit that trod many roads in the hands of eager and curious students. Ventricular fibrillation and especially its counterpart, defibrillation, stand out as subjects occupying his concern along the years. Many were the students recruited to such effort and long is the list of papers on the subject. Physiological signals attracted considerable part of his activities because one of his perennial mottos was measurement is essential in physiology. He has written thirteen books and over eight hundred scientific papers, receiving also several prizes and distinctions. Not only his interests stayed within the academic environment but an industrial hue was manifested in over 20 USA patents, all applied to medical use. History of science and technology was another area in which, often with Hebbel Hoff, he uncovered astounding and delightful information. It

  10. Leslie Ford, MD | Division of Cancer Prevention (United States)

    Dr. Leslie Ford built clinical cancer prevention research as a scientific field when few people were considering the possibility of prevention, and is recognized as a national and international leader in cancer prevention research. She has a passion for prevention and strong belief that all clinical science must, to the fullest extent possible, derive as a translation of basic

  11. Book Review: Leslie Holmes, Corruption: A Very Short Introduction

    DEFF Research Database (Denmark)

    Keremis, Anestis


    Book review of: Corruption. A Very Short Introduction / by Leslie Holmes. Oxford: Oxford University Press, 2015. 143pp., £7.99 (p/b), ISBN 9780199689699.......Book review of: Corruption. A Very Short Introduction / by Leslie Holmes. Oxford: Oxford University Press, 2015. 143pp., £7.99 (p/b), ISBN 9780199689699....

  12. Leslie Martin and the formal order

    Directory of Open Access Journals (Sweden)

    Jaime J. Ferrer Fores


    Full Text Available Abstract This paper analyzes the architecture of Sir Leslie Martin (1908-2000 and covers the intense professional career that starts with the Nursery School at Northwich, Cheshire (1937-1938 or the Alastair Morton house at Brampton (1938 which are ascribed to the orthodoxy of modern architecture, and  continues with the projects he planned as the architect responsible of the railway company for stations and railroad infrastructure rearrangements in the postwar, interventions that will prepare him for his architectural maturity stage which he crystallizes in buildings for the Royal Festival Hall in London (1948-1951, the Harvey Court, Cambridge (1958-1962, the auditoriums  for the Middleton Hall, University of Hull (1958 , the School of Music  (1974 and College (1979 at Cambridge University and his proposal for  the University of Bristol (1979 that illustrate the essential basis of his  coherent architectural career where the tradition of modern architecture, the spatial continuity and the formal order converge. This analysis of the works in the fifties, sixties and seventies illustrates the architect’s constants  through the chronological exploration of his works that reveal the  compositional mechanisms, the search for formal order and the correct spatial organization taking into account the functional requirements, the relationship with the site and the technological resources that determine his entire career which is characterized by formal consistency and architectural coherence.

  13. Leslie Peltier, Amateur Astronomer and Observer Extraordinaire (United States)

    Corbin, B. G.


    Leslie Copus Peltier, (Jan. 2, 1900-May 10, 1980) was called "the world's greatest non-professional astronomer" by none other than Harlow Shapley, and also referred to as the "the world's greatest living amateur astronomer". He began observing variable stars on March 1, 1918 with an observation of R. Leonis and at the time of his death had made a total of 132,123 observations of variable stars. These were reported to the AAVSO on a consecutive monthly basis stretching from 1918 to his death in 1980. As of October 2003, he was still on AAVSO's list of the top 25 observers in its history. Born on a farm near Delphos, Ohio, his parents were well read and their home was filled with books on different subjects, including nature guides. As a young man he studied the flora and fauna of the area and in 1915 began his study of the heavens with Vega being the first star he identified. After the purchase of a 2-inch spyglass, his observations of variable stars began to be noticed by professional astronomers and the AAVSO loaned him a 4-inch Mogey refractor; shortly thereafter Henry Norris Russell of Princeton loaned him via the AAVSO a 6-inch refractor, a comet seeker of short focus. He discovered 12 comets, 10 of which carry his name, and 6 novae or recurring novae. His design of the "Merry-Go-Round Observatory" was a novel approach with the whole observatory revolving around the observer while seated in his observing chair. Miami University (Ohio) later donated to him their 12-inch Clark refractor with its dome. His first book, Starlight Nights: The Adventures of a Star-Gazer, appeared in 1965. This autobiography, an ode to the joys of observing both the night sky and nature, was written in beautifully descriptive language that helped lead countless readers into astronomy. Departing from astronomy, in 1977 he published The Place on Jennings Creek. Written in the style of the 19th century naturalist, the book was devoted to his family's home, Brookhaven, and its natural

  14. Rigorous derivation from Landau-de Gennes theory to Ericksen-Leslie theory


    Wang, Wei; Zhang, Pingwen; Zhang, Zhifei


    Starting from Beris-Edwards system for the liquid crystal, we present a rigorous derivation of Ericksen-Leslie system with general Ericksen stress and Leslie stress by using the Hilbert expansion method.

  15. Book Review Counselling and Coping by Kerry Gibson, Leslie ...

    African Journals Online (AJOL)

    Book Review Counselling and Coping by Kerry Gibson, Leslie Swartz and Rob Sandenbergh. Alison Moultrie, Alison Moultrie. Abstract. 2002, Oxford University Press ISBN 0–19–571868 2. Journal of Child and. Adolescent Mental Health 2003, 15(1): 55. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL ...

  16. Evolutionary formalism from random Leslie matrices in biology

    International Nuclear Information System (INIS)

    Caceres, M.O.; Caceres-Saez, I.


    We present a perturbative formalism to deal with linear random matrix difference equations. We generalize the concept of the population growth rate when a Leslie matrix has random elements (i.e., characterizing the disorder in the vital parameters). The dominant eigenvalue of which defines the asymptotic dynamics of the mean value population vector state, is presented as the effective growth rate of a random Leslie model. This eigenvalue is calculated from the largest positive root of a secular polynomial. Analytical (exact and perturbative calculations) results are presented for several models of disorder. A 3 x 3 numerical example is applied to study the effective growth rate characterizing the long-time dynamics of a population biological case: the Tursiops sp. (author)

  17. An impulsive predator-prey system with modified Leslie-Gower and Holling type II schemes

    International Nuclear Information System (INIS)

    Guo Hongjian; Song Xinyu


    An impulsive predator-prey system with modified Leslie-Gower and Holling-type II schemes is presented. By using the Floquet theory of impulsive equation and small amplitude perturbation method, the globally asymptotical stability of prey-free positive periodic solution and the permanence of system are discussed. The corresponding threshold conditions are obtained respectively. Finally, numerical simulations are given

  18. Leslie S. Greenberg: Award for Distinguished Professional Contributions to Applied Research (United States)

    American Psychologist, 2012


    Presents a short biography of the 2012 winner of the American Psychological Association's Award for Distinguished Professional Contributions to Applied Research. Leslie S. Greenberg is an exemplary scientist-practitioner whose pioneering work has significantly altered the landscape of the field of psychotherapy research and practice. His seminal…

  19. A Discrete Numerical Scheme of Modified Leslie-Gower With Harvesting Model

    Directory of Open Access Journals (Sweden)

    Riski Nur Istiqomah Dinnullah


    Full Text Available Recently, exploitation of biological resources and the harvesting of two populations or more are widely practiced, such as fishery or foresty. The simplest way to describe the interaction of two species is by using predator prey model, that is one species feeds on another. The Leslie-Gower predator prey model has been studied in many works. In this paper, we use Euler method to discretisize the modified Leslie-Gower with harvesting model. The model consists of two simultanious predator prey equations. We show numerically that this discrete numerical scheme model is dynamically consistent with its continuous model only for relatively small step-size. By using computer simulation software, we show that equlibrium points can be stable, saddles, and unstable. It is shown that the numerical simulations not only illustrate the results, but also show the rich dynamics behaviors of the discrete system.

  20. Dynamics of Leslie-Gower type generalist predator in a tri-trophic food web system

    Czech Academy of Sciences Publication Activity Database

    Priyadarshi, Anupam; Gakkhar, S.


    Roč. 18, č. 11 (2013), s. 3202-3218 ISSN 1007-5704 R&D Projects: GA MŠk(CZ) EE2.3.30.0032 Institutional support: RVO:60077344 Keywords : Leslie-Gower model * hopf-bifurcation * periodic orbits Subject RIV: EH - Ecology, Behaviour Impact factor: 2.569, year: 2013

  1. The work of Leslie Valiant: alle die Strassen führen nach Strassen

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    J. Andrés Montoya


    Full Text Available . This year Leslie VALIANT becomes sixty five years old; we celebrate his fest with this work in which we analyze some of his major achievements. We focus our attention on those of his works for which a strong influence of Volker Strassen can be easily detected. Strassen’s work has had a strong and lasting influence on Valiant. It does not means, as the title could suggest, that the manyfaced, relevant and complex work of Leslie Valiant can be understood as a corollary to Strassen. Resumen. Este año Leslie VALIANT cumple 65 años y nosotros queremos celebrar este importante aniversario con este trabajo en el que se analiza su obra. Centramos nuestra atención en aquellos de sus trabajos en los que una clara influencia de Volker STRASSEN puede ser detectada. Es patente la influencia de Strassen en la obra de Valiant, pero esto no quiere decir que el trabajo de Valiant, complejo y multifacético, sea un simple corolario a la obra del primero.

  2. "Vältimatud nuhtlused" : August Komendant, Louis I. Kahn ja arhitektuuri ning insenerikunsti keerulised suhted / Thomas Leslie

    Index Scriptorium Estoniae

    Leslie, Thomas


    Artikkel põhineb Thomas Leslie Kuressaares Louis Kahni päevadel peetud ettekandel. Louis Kahni koostöös August Komendandiga projekteeritud hoonetest pikemalt Richardsi Meditsiiniliste Uuringute laboratooriumist, Salki bioloogianistituudist (1959-1965, La Jolla, Kalifornia) ja Kimbelli kunstimuuseumist (1966-1972, Texas, Fort Worth). Bibl. lk. 75

  3. A modified Leslie-Gower predator-prey interaction model and parameter identifiability (United States)

    Tripathi, Jai Prakash; Meghwani, Suraj S.; Thakur, Manoj; Abbas, Syed


    In this work, bifurcation and a systematic approach for estimation of identifiable parameters of a modified Leslie-Gower predator-prey system with Crowley-Martin functional response and prey refuge is discussed. Global asymptotic stability is discussed by applying fluctuation lemma. The system undergoes into Hopf bifurcation with respect to parameters intrinsic growth rate of predators (s) and prey reserve (m). The stability of Hopf bifurcation is also discussed by calculating Lyapunov number. The sensitivity analysis of the considered model system with respect to all variables is performed which also supports our theoretical study. To estimate the unknown parameter from the data, an optimization procedure (pseudo-random search algorithm) is adopted. System responses and phase plots for estimated parameters are also compared with true noise free data. It is found that the system dynamics with true set of parametric values is similar to the estimated parametric values. Numerical simulations are presented to substantiate the analytical findings.

  4. The "Immortal" Boilermaker: Exploring the Forgotten History of Harry Guyer Leslie

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    Elizabeth Hudson


    Full Text Available As Purdue University grows, the school’s rich history is sometimes neglected in lieu of developments in present-day interests and needs. Often, the only remaining evidence of community events and distinguished, local individuals are memorials, archive collections, and rarely seen documents. Many communities have access to such documents; however, as the available access to these collections slowly becomes unrecognized, so does the history and remembrance of the individuals and events. The purpose of this research was to determine the source of a small, tarnished trophy in Orlando Itin’s sports memorabilia collection in Bruno’s Pizza Restaurant. This trophy stands as one of the unrecognized items of living history in West Lafayette, Indiana, which spurred the research and development of a further question: how can community historians discover the concealed facts of their local history? Throughout this research, personal interviews and careful searches were conducted through Purdue University’s Virginia Kelly Karnes Archives and Special Collections Research Center, local collections, online databases, and academic journals to recollect the memory of the recipient of the forgotten trophy, former Indiana Governor Harry Guyer Leslie. Leslie was not only a Purdue graduate, but a survivor of the infamous 1903 Purdue Wreck. He made numerous contributions to the University and overcame adversity to become governor of Indiana, but his memory and contributions to the University and state are barely documented. This article explores not only Governor Leslie’s history, but also examines the methods community historians can use to conduct their own local research.

  5. Mortality rate estimation for eelgrass Zostera marina (Potamogetonaceae using projections from Leslie matrices

    Directory of Open Access Journals (Sweden)

    Olga Flores Uzeta


    Full Text Available The main goal of this study is to provide estimations of mean mortality rate of vegetative shoots of the seagrass Zostera marina in a meadow near Ensenada Baja California, using a technique that minimizes destructive sampling. Using cohorts and Leslie matrices, three life tables were constructed, each representing a season within the period of monthly sampling (April 1999 to April 2000. Ages for the cohorts were established in terms of Plastochrone Interval (PI. The matrices were projected through time to estimate the mean total number of individuals at time t, n(t as well as mortality. We found no statistical differences between observed and predicted mean values for these variables (t=-0.11, p=0.92 for n(t and t=0.69, p=0.5 for mean rate of mortality. We found high correlation coefficient values between observed and projected values for monthly number of individuals (r=0.70, p=0.007 and monthly mortality rates (r=0.81, p=0.001. If at a certain time t a sudden environmental change occurs, and as long as the perturbation does not provoke the killing of all the individuals of a given age i for 0 ≤ i ≤ x - 1, there will be a prevailing number of individuals of age or stage x at a time t+1. This nondestructive technique reduces the number of field visits and samples needed for the demographic analysis of Z. marina, and therefore decreases the disturbance caused by researches to the ecosystem. Rev. Biol. Trop. 56 (3: 1015-1022. Epub 2008 September 30El propósito principal de este estudio es el de proveer estimaciones de tasas promedio de mortalidad de tallos vegetativos de Zostera marina en una pradera cercana a Ensenada Baja California, utilizando una técnica que minimiza los muestreos destructivos para estos pastos marinos. Mediante la utilización de cohortes y matrices de Leslie, se construyeron tres tablas de vida, cada una representando a una estación dentro de período anual de muestreos mensuales (Abril 1999 a Abril 2000. Las edades

  6. Keeping Secrets: Leslie E. Keeley, the Gold Cure and the Nineteenth-Century Neuroscience of Addiction. (United States)

    Hickman, Timothy A


    Dr Leslie E. Keeley was perhaps the world's most famous addiction cure doctor at the turn of the twentieth century, but mainstream medicine dismissed him as a quack because he dispensed a secret cure. The article aims to describe Keeley's now largely forgotten story and to draw attention to the role of contextual issues in the acceptance or rejection of any theory of addiction, particularly the neuroscientific theories of the early twenty first century. This study is a qualitative assessment and contextualisation of historical documents. Its main sources are archival and are for the most part unknown to historians. The article also offers intellectual and historical context that is drawn from leading historical and sociological analyses. Keeley's addiction cure was dismissed as quackery because it failed to meet the changing standards of late-nineteenth century professional medicine. This begs us to consider contextual issues in any assertion of the viability of addiction therapeutics, in the present as well the past. Keeley's near erasure from the historical record was a consequence of a broader, late-nineteenth century medical power struggle that took precedence over the testimony of tens of thousands of satisfied patients who claimed that Keeley's cure worked. Context matters in the assessment of the viability of theories of addiction from the past but also from the present. Historians and social scientists are well placed to make those assessments. This article is protected by copyright. All rights reserved.

  7. Stability and Optimal Harvesting of Modified Leslie-Gower Predator-Prey Model (United States)

    Toaha, S.; Azis, M. I.


    This paper studies a modified of dynamics of Leslie-Gower predator-prey population model. The model is stated as a system of first order differential equations. The model consists of one predator and one prey. The Holling type II as a predation function is considered in this model. The predator and prey populations are assumed to be beneficial and then the two populations are harvested with constant efforts. Existence and stability of the interior equilibrium point are analysed. Linearization method is used to get the linearized model and the eigenvalue is used to justify the stability of the interior equilibrium point. From the analyses, we show that under a certain condition the interior equilibrium point exists and is locally asymptotically stable. For the model with constant efforts of harvesting, cost function, revenue function, and profit function are considered. The stable interior equilibrium point is then related to the maximum profit problem as well as net present value of revenues problem. We show that there exists a certain value of the efforts that maximizes the profit function and net present value of revenues while the interior equilibrium point remains stable. This means that the populations can live in coexistence for a long time and also maximize the benefit even though the populations are harvested with constant efforts.

  8. Cartographies of the Voice: Storying the Land as Survivance in Native American Oral Traditions

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    Ivanna Yi


    Full Text Available This article examines how Native places are made, named, and reconstructed after colonization through storytelling. Storying the land is a process whereby the land is invested with the moral and spiritual perspectives specific to Native American communities. As seen in the oral traditions and written literature of Native American storytellers and authors, the voices of indigenous people retrace and remap cartographies for the land after colonization through storytelling. This article shows that the Americas were storied by Native American communities long before colonial contact beginning in the fifteenth century and demonstrates how the land continues to be storied in the present as a method of decolonization and cultural survivance. The article examines manifestations of the oral tradition in multiple forms, including poetry, interviews, fiction, photography, and film, to demonstrate that the land itself, through storytelling, becomes a repository of the oral tradition. The article investigates oral narratives from precontact and postcolonial time periods and across numerous nations and geographical regions in the Americas, including stories from the Mayan Popol Vuh; Algonkian; Western Apache; Hopi; Haudenosaunee/Iroquois; and Laguna Pueblo stories; and the contemporary poetry and fiction of Joy Harjo (Mvskoke/Creek Nation and Leslie Marmon Silko (Laguna Pueblo.

  9. Catharine Sedgwick’s Hope Leslie (1827 and the Revision of the Puritan Past

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    Teresa Requena Pelegrí


    Full Text Available Catharine Maria Sedgwick’s texts and achievement have been long overshadowed by the undisputed recognition of some of her male contemporaries. James Fenimore Cooper, Washington Irving or William Cullen Bryant have received all the credit for having shaped -and for many, created- U.S. literature. However, Sedgwick’s contribution to the development of a specific native tradition in American letters is undeniable. Long before Ralph Waldo Emerson’s call for a specifically national subject-matter, Sedgwick was consciously giving her texts an American perspective by combining the techniques used in sentimental fiction with the historical romance. Set in colonial times, Hope Leslie or Early Times in the Massachusetts (1827 constitutes one of Sedgwick’s poignant explorations of the Puritan past of the country and its interrelation with issues of gender and race. By fusing Puritan historical accounts with fiction, Sedgwick’s technique succeeds in foregrounding the partiality of historical accounts in opposition to their supposedly objective exposition of facts and in this way the text manages to challenge Puritan self-righteous historiography. Moreover, the use of the Puritan past as material for her fiction together with the inclusion of Native American characters makes Sedgwick an extremely interesting foil to other contemporaries such as Nathaniel Hawthorne or James Fenimore Cooper. This paper wishes to explore Sedgwick’s version of the Puritan presence in the American colonies and compare it with Nathaniel Hawthorne’s to demonstrate how the former made gender indistinguishable form the construction of a national narrative. The paper also tackles Sedgwick’s sexual and racial politics in her treatment of fully developed Native American characters thus constituting an enlightening counterpart to the stereotypical and reductive portrayal found in James Fenimore Cooper’s work.

  10. Mixed methods in health sciences research: a practical primer [Leslie Curry and Marcella-Nunez Smith (Sage Publishing, 2015)


    Nelson, David


    Written by internationally-recognised health research experts, Leslie Curry and Marcella Nunez-Smith, this book aims to show researchers and students in the health sciences how to design, conduct, review and use mixed methods. Given the increased use of mixed methods in the health sciences, this text is timely and unique in that it offers a discipline-specific focus that is both relevant and practical. The book has a logical structure and is broken down into four parts: (1) an overview of ...

  11. Leslie Cemetery and Francisco distributary fluvial channels in the Petersburg Formation (Pennsylvanian) of Gibson County, Indiana, USA

    Energy Technology Data Exchange (ETDEWEB)

    Eggert, D L


    The Leslie Cemetery Channel is a small distributary fluvial channel that is partly contemporaneous with the Springfield Coal member of the Petersburg Formation (Pennsylvanian) and splits the seam into two seams. This channel is 1-6 miles (1.6-10 km) wide and extends 30 miles (48 km) in the subsurface. Overbank and channel fill deposits consisting of sandstone, siltstone, and mudstone split the coal into two seams up to 40-50 ft (12-15 m) apart in places. The lower seam is a low-sulphur coal. Adjacent to this channel is the unsplit coal, which is as much as 9 ft (3 m) thick. Beneath the Leslie Cemetery Channel and the Springfield coal is the slightly older Francisco Channel (new name), which is younger than the next lower coal. This channel is filled with a fining-upward sandstone as much as 75 ft (23 m) thick. The positions of these stacked channels were determined by the differential compaction of earlier sediments. 20 references.

  12. [On the problems of the evolutionary optimization of life history. II. To justification of optimization criterion for nonlinear Leslie model]. (United States)

    Pasekov, V P


    The paper considers the problems in the adaptive evolution of life-history traits for individuals in the nonlinear Leslie model of age-structured population. The possibility to predict adaptation results as the values of organism's traits (properties) that provide for the maximum of a certain function of traits (optimization criterion) is studied. An ideal criterion of this type is Darwinian fitness as a characteristic of success of an individual's life history. Criticism of the optimization approach is associated with the fact that it does not take into account the changes in the environmental conditions (in a broad sense) caused by evolution, thereby leading to losses in the adequacy of the criterion. In addition, the justification for this criterion under stationary conditions is not usually rigorous. It has been suggested to overcome these objections in terms of the adaptive dynamics theory using the concept of invasive fitness. The reasons are given that favor the application of the average number of offspring for an individual, R(L), as an optimization criterion in the nonlinear Leslie model. According to the theory of quantitative genetics, the selection for fertility (that is, for a set of correlated quantitative traits determined by both multiple loci and the environment) leads to an increase in R(L). In terms of adaptive dynamics, the maximum R(L) corresponds to the evolutionary stability and, in certain cases, convergent stability of the values for traits. The search for evolutionarily stable values on the background of limited resources for reproduction is a problem of linear programming.

  13. 7 March 2013 -Stanford University Professor N. McKeown FREng, Electrical Engineering and Computer Science and B. Leslie, Creative Labs visiting CERN Control Centre and the LHC tunnel with Director for Accelerators and Technology S. Myers.

    CERN Multimedia

    Anna Pantelia


    7 March 2013 -Stanford University Professor N. McKeown FREng, Electrical Engineering and Computer Science and B. Leslie, Creative Labs visiting CERN Control Centre and the LHC tunnel with Director for Accelerators and Technology S. Myers.

  14. “There is nothing better than a theory”: A few remarks on the theoretical practice of contemporary avantgarde women writers (Lyn Hejinian, Leslie Scalapino, Carla Harryman)


    Małgorzata Myk


    The essay discusses theoretical practices of three major Americanexperimental women writers associated with L=A=N=G=U=A=G=E poets LynHejinian, Leslie Scalapino, and Carla Harryman, who played a crucial role in shapingthe present-day critical and theoretical literary debate regarding the status of formallyradical literature engaged in questions of feminist epistemology and written bywomen. Devoted to language and its ideological dimension, their work is based ona wager that poetic practice is ...

  15. The Female Population Growth Projection Year 2021 in Trenggalek Regency by Leslie Matrix Model on the Birth Rate and Life Expectancy

    Directory of Open Access Journals (Sweden)

    Dewi Anggreini


    Full Text Available This research aims to determine the number of female residents in Trenggalek Regency in 2021 based on data on birth rate and life expectancy. The use of eigenvalues and eigenvectors aims to determine the dividing age distribution by Leslie matrix model. The eigenvectors are used to determine the number of female populations of each age interval, while the eigenvalues are used to determine population growth rates. The research method used is to determine the subject of research. The next stage is to collect research data, then analyze the data and last draw conclusions. The research data is obtained from BPS Kabupaten Trenggalek and BPS East Java Province that is data of woman population from year 2010-2015. The result of this research using Leslie matrix model for female population in Trenggalek Regency that is discrete model. The discrete model is divided into fourteen age intervals constructed using the birthrate and life expectancy. The conclusions of the study showed that the number of female population in Trenggalek Regency tended to increase with positive eigen value greater than one. In other words, the growth rate of female population in Trenggalek Regency tends to be positive. The success of Leslie's matrix model is the application of case studies in predicting the number of female populations in Trenggalek District by 2021 using the MAPLE 16 Program.

  16. Complex dynamics of a stochastic discrete modified Leslie-Gower predator-prey model with Michaelis-Menten type prey harvesting

    Directory of Open Access Journals (Sweden)

    A. Elhassanein


    Full Text Available This paper introduced a stochastic discretized version of the modified Leslie-Gower predator-prey model with Michaelis-Menten type prey harvesting. The dynamical behavior of the proposed model was investigated. The existence and stability of the equilibria of the skeleton were studied. Numerical simulations were employed to show the model's complex dynamics by means of the largest Lyapunov exponents, bifurcations, time series diagrams and phase portraits. The effects of noise intensity on its dynamics and the intermittency phenomenon were also discussed via simulation.

  17. Popmuusika / Leslie Laasner

    Index Scriptorium Estoniae

    Laasner, Leslie


    Uutest heliplaatidest "Bossa n' Stones", Anti-Flag "For Blood And Empire", Nightmares On Wax "In A Space Outta Sound", The Futureheads "New And Tributes", Madlib "The Beat Konducta", Live "Songs From Black Mountain"

  18. Predicting the effect of ionising radiation on biological populations: testing of a non-linear Leslie model applied to a small mammal population

    International Nuclear Information System (INIS)

    Monte, Luigi


    The present work describes the application of a non-linear Leslie model for predicting the effects of ionising radiation on wild populations. The model assumes that, for protracted chronic irradiation, the effect-dose relationship is linear. In particular, the effects of radiation are modelled by relating the increase in the mortality rates of the individuals to the dose rates through a proportionality factor C. The model was tested using independent data and information from a series of experiments that were aimed at assessing the response to radiation of wild populations of meadow voles and whose results were described in the international literature. The comparison of the model results with the data selected from the above mentioned experiments showed that the model overestimated the detrimental effects of radiation on the size of irradiated populations when the values of C were within the range derived from the median lethal dose (L 50 ) for small mammals. The described non-linear model suggests that the non-expressed biotic potential of the species whose growth is limited by processes of environmental resistance, such as the competition among the individuals of the same or of different species for the exploitation of the available resources, can be a factor that determines a more effective response of population to the radiation effects. -- Highlights: • A model to assess the radiation effects on wild population is described. • The model is based on non-linear Leslie matrix. • The model is applied to small mammals living in an irradiated meadow. • Model output is conservative if effect-dose factor estimated from L 50 is used. • Systemic response to stress of populations in competitive conditions may be more effective

  19. New Interpretations of Native American Literature: A Survival Technique. (United States)

    Buller, Galen


    Uses examples from the work of several Native American authors, including N. Scott Momaday and Leslie Silko, to discuss five unique elements in American Indian literature: reverence for words, dependence on a sense of place, sense of ritual, affirmation of the need for community, and a significantly different world view. (SB)

  20. “There is nothing better than a theory”: A few remarks on the theoretical practice of contemporary avantgarde women writers (Lyn Hejinian, Leslie Scalapino, Carla Harryman

    Directory of Open Access Journals (Sweden)

    Małgorzata Myk


    Full Text Available The essay discusses theoretical practices of three major Americanexperimental women writers associated with L=A=N=G=U=A=G=E poets LynHejinian, Leslie Scalapino, and Carla Harryman, who played a crucial role in shapingthe present-day critical and theoretical literary debate regarding the status of formallyradical literature engaged in questions of feminist epistemology and written bywomen. Devoted to language and its ideological dimension, their work is based ona wager that poetic practice is a socially engaged strategy of intervention (Harryman,and as such functions as a language-oriented feminist epistemology. Hejinian,Scalapino, and Harryman created a significant literary and theoretical body of workthat includes complex genre-bending hybrid texts deeply rooted in contemporaryfeminist discourses and preoccupied with such issues as production of knowledge,meaning, identity, gender, and sexuality, hidden ideological mechanismsof the conventional narrative, and the imperative of its constant refiguration.The article is also an attempt to see their work in a broader context of feministthought, ranging from écriture féminine, through Judith Butler’s and Denise Riley’scritiques of identity politics, to the posthumanist horizon of Donna Haraway’scyborg writing.

  1. OBITUARY: Leslie E Howlett, 1904 1992 (United States)

    Preston-Thomas, H.


    Dr L E Howlett of Ottawa (Canada), who died in his 88th year on 21 January 1992, was a member of the Comité International des Poids et Mesures (CIPM) from 1955 to 1968 and was President of the Comité Consultatif pour la Définition du Mètre (CCDM) from 1956. He was elected Vice-President of the CIPM in 1960 and President in 1964, and was made an honorary member following his retirement in 1968. After taking degrees from the universities of British Colombia, Toronto and McGill, Howlett joined Canada's National Research Council in 1931, remaining with that institution for virtually all of his working life. He initially set up, singlehandedly, an optics laboratory at the NRC, being joined by a technician in 1932. By the beginning of the war in September 1939 the laboratory had a staff of four, and this was the basis from which, under Howlett's direction, and with no prior optical production in the country, a Canadian optical industry was generated, with samples of a variety of optical instruments being completed by the end of April 1940, and many thousands of precision optical components being manufactured during the course of the war. Much of this precision optical work involved testing, measurement and calibration. Howlett's interests in such work were substantially enlarged when in 1948 he was put in charge, as Assistant Director, of applied research in the Division of Physics. This was, in effect, to be in charge of Canada's standards laboratory, and he then was naturally a candidate for membership of the CIPM. On the subsequent establishment of the Division of Applied Physics Howlett became its Director, a position he retained until his retirement. It was under Howlett's direction that Canada progressed from a state of having only commercial and surveying standards of very moderate precision to that of possessing a world-class standards laboratory. During the period of his membership of the CIPM, he was an enthusiastic proponent of the establishment of the ionizing radiation laboratory at the BIPM, and of the introduction of quantum metrology to the SI in the form of the krypton-86 definition of the metre, adopted in 1960 during his presidency of the CCDM, and the caesium-133 definition of the second in 1967. He was responsible for establishing Metrologia, under the auspices of the CIPM, being editor from its inception in 1965 until his retirement. For these, and for many other related services, Canada and the world measurement community will remember him and his work with gratitude.

  2. Leslie ja Naomi juhtum / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-


    Readingi Ülikoolis (Inglismaa) toimunud feminismikonverentsiga kaasnenud näitusest "Virtue and Vulgarity" ja selle silmapaistvamatest töödest. Analüüsitakse naiste ja meeste kunstile omaseid erinevusi ning võimalust aktsepteerida feminiinsusena ka malbust, alalhoidlikkust. Esitati Mare Tralla CD-ROM ""

  3. Reverse perspective as a narrative technique in Amerindian prosaic texts

    Directory of Open Access Journals (Sweden)

    Volkova Svitlana


    Full Text Available The paper focuses on the narrative perspective of interpreting the ethno-cultural meanings hidden in the characters of prosaic texts written by contemporary Amerindian writers (N.S. Momaday, Linda Hogan, Leslie Silko and others. The main idea raised in their works is to highlight ethno-cultural traditions, values, ceremonies and understanding the world. The main author’s interest is paid to the reverse perspective as a narrative technique of interpretation the central character as ethno-cultural symbol.

  4. Pekingi punased olümpiamedalid / Leslie Leino

    Index Scriptorium Estoniae

    Leino, Leslie


    Autor käsitleb Eesti poliitikute artikleid, mis puudutasid Hiina olümpiamängude boikottimise teemat. Ta leiab, et peaksime inimõiguste ja muid probleeme tõstatama ratsionaalsetes piirides. Hiinas endas väideldakse juba ammu inimõiguste teemal. Mõõdukas probleemidele osutamine näitab Eesti selgroogu

  5. LESLIE A. WHITE Y LA MEDICIÓN OBJETIVA DEL CAMBIO CULTURAL DE LA HUMANIDAD (Leslie A. White and the Objective Measurement of Human Culture Change

    Directory of Open Access Journals (Sweden)

    Pascual Izquierdo-Egea


    Full Text Available Esta breve comunicación arroja luz sobre una cuestión tan fundamental como la medición objetiva del cambio cultural de la humanidad a través del registro funerario. Aunque son numerosas las evidencias materiales que confirman la significatividad y fiabilidad de la técnica cuantitativa empleada para medir el avance o retroceso de las sociedades antiguas, aquí solo se muestran los datos de la serie temporal proveniente de la cuenca del río Balsas, México, representativa de la Mesoamérica prehispánica. ENGLISH: This brief communication sheds light on the fundamental question of the objective measurement of human culture change through the mortuary record. Although there are abundant material evidence that confirms the significance and reliability of the quantitative technique used to measure the advancement or retreat of ancient societies, only the time series data from the basin of the Balsas River, Mexico, representative of pre-Hispanic Mesoamerica, are shown here.

  6. Developing digital vegetation for central hardwood forest types: A case study from Leslie County, KY (United States)

    Bo Song; Wei-lun Tsai; Chiao-ying Chou; Thomas M. Williams; William Conner; Brian J. Williams


    Digital vegetation is the computerized representation, with either virtual images or animations, of vegetation types and conditions based on current measurements or ecological models. Digital vegetation can be useful in evaluating past, present, or future land use; changes in vegetation linked to climate change; or restoration efforts. Digital vegetation can be...

  7. Hamid Karzai on küll Afganistani riigipea, aga Massoud on kangelane / Leslie Leino

    Index Scriptorium Estoniae

    Leino, Leslie


    Afganistani valimistel võitsid opositsionäärid, tugevaim figuur nende hulgas on Ahmad Shah Massoudi kunagine kaasvõitleja Yunus Qanun, kelle siht on võõrväed riigist välja viia ja riik ühendada. Ameeriklased ja nende liitlased on ärevil, sest Qanun pole võõrvägede hulgas populaarne. Lisa: Põhimõtteliselt ameeriklaste vastu. Vt. samas: Afganistanis alustas pärast 30-aastast pausi tööd parlament

  8. Informe científico de Beca de Perfeccionamiento: Valdivia Torres, Lesly Spring (2013) 


    Valdivia Torres, Lesly Spring


    La ingesta aguda de dieta alta en grasa activa la expresión de c-Fos en áreas cerebrales relacionadas al placer. El consumo de alimentos de alta palatabilidad es una experiencia gratificante para la mayoría de los animales, incluyendo los seres humanos. Varios estudios sugieren que el contexto actual en el que vivimos, donde dichos alimentos son de fácil acceso, promueve el consumo excesivo de calorías que pueden conducir a la obesidad o trastornos de la ali...

  9. Translating bioassay results to field population responses using a Leslie-matrix model for the marine amphipod Corophium volutator

    NARCIS (Netherlands)

    Smit, M.G.D.; Kater, B.J.; Jak, R.G.; Heuvel-Greve, van den M.J.


    Bioassays can be used for the assessment of sediment contamination. The response is classified based on a statistical scale indicating a certain effect percentage being significantly different from the controls (e.g. mortality classes of 0¿10%, 10¿20% etc.). The ecological relevance of this

  10. Hispaanias võtab võimust uus põlvkond / Leslie Crawford, Mark Mulligan ; tõlk. Erik Aru

    Index Scriptorium Estoniae

    Crawford, Leslie


    Mitmel põhjusel on Hispaania äri muutunud rahvusvahelisemaks, selle taga on uus ärijuhtide põlvkond, kes on hariduse omandanud mõnes ingliskeelses maailma elitaarses koolis. Lisa: Hispaania imeb 500-euroseid

  11. Organic Nitrate Metabolism and Action: Toward a Unifying Hypothesis and the Future --- A Dedication to Professor Leslie Z. Benet (United States)

    Page, Nathaniel A.; Fung, Ho-Leung


    This review summarizes the major advances that had been reported since the outstanding contributions that Professor Benet and his group had made in the 1980’s and 1990’s concerning the metabolism and pharmacologic action of organic nitrates (ORN). Several pivotal studies have now enhanced our understanding of the metabolism and the bioactivation of ORN, resulting in the identification of a host of cysteine-containing enzymes that can carry out this function. Three isoforms of aldehyde dehydrogenase, all of which with active catalytic cysteine sites, are now known to metabolize, somewhat selectively, various members of the ORN family. The existence of a long-proposed but unstable thionitrate intermediate from organic nitrate metabolism has now been experimentally observed. ORN-induced thiol oxidation in multiple proteins, called the “Thionitrate Oxidation Hypothesis”, can be used not only to explain the phenomenon of nitrate tolerance, but also the various consequences of chronic nitrate therapy, viz., rebound vasoconstriction, and increased morbidity and mortality. Thus, a unifying biochemical hypothesis can account for the myriad of pharmacological events resulting from nitrate therapy. Optimization of future uses of ORN in cardiology and other diseases could benefit from further elaboration of this unifying hypothesis. PMID:23670666

  12. Global Asymptotic Stability of a Predator-Prey Model with Modified Leslie-Gower and Holling-Type II Schemes

    Directory of Open Access Journals (Sweden)

    Shengbin Yu


    Full Text Available We study the predator-prey model proposed by Aziz-Alaoui and Okiye (Appl. Math. Lett. 16 (2003 1069–1075 First, the structure of equilibria and their linearized stability is investigated. Then, we provide two sufficient conditions on the global asymptotic stability of a positive equilibrium by employing the Fluctuation Lemma and Lyapunov direct method, respectively. The obtained results not only improve but also supplement existing ones.

  13. Lesly Bessière, Les romancières françaises, 1870-1900 : approche à travers l'exemple de Jeanne Marni

    Directory of Open Access Journals (Sweden)

    Lesly Bessière


    Full Text Available Les romancières françaises publiant entre 1870 et 1900, entre George Sand et Colette, sont les grandes oubliées des histoires littéraires ainsi que de l’historiographie. Leurs vies et leurs œuvres méritent pourtant d’être redécouvertes.Depuis les virulents textes misogynes de la fin du XIXe siècle signés Barbey d’Aurevilly, Albert Cim ou encore Dumas fils, « les bas-bleus » n’ont plus guère intéressé l’historiographie. Peu d’historiens y consacrent des ouvrages avant les études pluridisciplin...

  14. 75 FR 24944 - Adequacy Status of the Milwaukee-Racine, Door County, Manitowoc County, and Sheboygan County... (United States)


    ... 5, 77 West Jackson Boulevard, Chicago, Illinois 60604, (312) 353-6680, FURTHER INFORMATION CONTACT: Michael Leslie, Environmental Engineer, Criteria Pollutant Section (AR-18J...

  15. 75 FR 26225 - Adequacy Status of the Chicago, Illinois Area Submitted 8-Hour Ozone Redesignation and... (United States)


    ... Agency, Region 5, 77 West Jackson Boulevard, Chicago, Illinois 60604 (312) 353-6680, leslie.michael@epa..., 2010. FOR FURTHER INFORMATION CONTACT: Michael Leslie, Environmental Engineer, Criteria Pollutant...

  16. 78 FR 16401 - Institutional Review Boards; Correcting Amendments (United States)


    .... 56.107 IRB membership. (a) * * * In addition to possessing the professional competence necessary to... professional conduct and practice. * * * * * * * * Dated: March 12, 2013. Leslie Kux, Assistant Commissioner...

  17. A Reminiscence (United States)

    Gobind Khorana, H.


    Leslie Orgel and Francis Crick with Gobind Khorana in Madison, Wisconsin (December 1965). I first met Leslie at the Endicott House (MIT) in February 1964. Leslie was then spending a period of time at MIT and the occasion was a party for him. During our conversation, Leslie talked about starting some experimental work. He seemed to be particularly interested in polyphosphates and the chemical activation of small molecules (building blocks). Shortly after his move to the Salk Institute in the Fall of 1964 I visited him in January 1965. He already had a lab going. I remember meeting Jim Ferris, in particular, and John Sulston sometime later. That particular time was exciting for my research as well. We had the first results on the Genetic Code using the chemical-biochemical approach that my lab had developed. Francis Crick was also at the Salk Institute during the time of my visit. Both Leslie and Francis were very excited by my results and they began to ask a lot of questions and gave me a whole lot of suggestions about further experiments. In fact, my thinking and planning of things that we were doing were so scrutinized and clarified during these discussions that, it seemed to me, my own group had only to turn out all the experiments that were needed. These interactions with Francis and Leslie continued intensively throughout that year and later. In fact, both Leslie and Francis accepted my invitation to Madison in December 1965 for more discussions. Since those early days of the Salk Institute, I have made numerous visits over the years to Leslie and his research group. It has always been very exciting to learn about the many discoveries bearing on chemical evolution that have unfolded from Leslie's research group. In addition, I have always benefitted from the insightful comments that Leslie invariably provided on my own research. I look forward to our continued interactions and friendship in the future. Leslie, A Happy Birthday!

  18. 75 FR 18256 - Petition for Exemption; Summary of Petition Received (United States)


    ... Federal holidays. FOR FURTHER INFORMATION CONTACT: Mr. Leslie B. Taylor, phone (816) 329- 4134, fax (816) 320-4090, e-mail . This notice is published pursuant to 14 CFR 11.85. Issued... Affected: 14 CFR 23.783(f)(1). Description of Relief Sought: Hawker Beechcraft Corporation (HBC) requests...

  19. 75 FR 34953 - Existence of Proposed Airworthiness Design Standards for Acceptance Under the Primary Category... (United States)


    ... Locust Street, Room 301, Kansas City, MO 64106. FOR FURTHER INFORMATION CONTACT: Mr. Leslie B. Taylor..., FAA; telephone number (816) 329-4134, fax number (816) 329-4090, e-mail at, low performance personal aircraft. Section 21.17(f) provides a means for applicants to propose...

  20. 75 FR 16878 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Notice of Filing of... (United States)


    ..., Saber Partners, LLC (``Saber Partners'') to Mr. Pica, dated July 9, 2008; Leslie M. Norwood, Managing... CEO, Saber Partners to Mr. Pica, dated July 9, 2008; Leslie M. Norwood, Managing Director and... Notice, Saber Partners identified this statistic as one that ``can give great insight into the liquidity...

  1. Loovmajanduse kriitika / interv. Ave Randviir

    Index Scriptorium Estoniae


    Kiasma nüüdiskunstimuuseumis toimunud seminarist "Critique of Creative Industries". Kiasma direktor Tuula Karjalainen ning professorid Esther Leslie ja Angela McRobbie vastavad küsimustele, mis on seotud loomemajanduse ja selle kriitikaga

  2. Kuula. Kuu artist Duffy. Kuu plaat / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-


    Briti lauljast Aimee Anne Duffy'st. Heliplaatidest: Leslie Da Bass "Nights By Open Windows", Janet Jackson "Discipline", Jack Johnson "Sleep Trough The Static", R.E.M. "Accelerate", Moby "Last Night", Gnarls Barkley "The Odd Couple"

  3. Plaadid / Rein Vader, Heidi Purga, Tiiu Laks...[jt.

    Index Scriptorium Estoniae


    Uutest heliplaatidest Nick Cave & The Bad Seeds "Dig, Lazarus, Dig!", Erykah Badu "New Amerikah Part One", Leslie da Bass "Nights By Open Windows", Jack Johnson "Sleep Througth The Static", Janet Jackson "Discipline", "Rock & Roll City"

  4. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ...

  5. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ...

  6. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ...

  7. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ...

  8. 76 FR 68500 - Performance Review Board Appointments (United States)


    ...-Bartels, Leslie Ishee, Mary Katherine Iudicello, Fay Jackson, Andrew Jacobson, Rachel Keable, Edward..., Bernard More, Robert Mulhern, Thomas Nedd, Michael O'Dell, Margaret Owens, Glenda Palma, Juan Payne...

  9. 78 FR 54200 - Approval and Promulgation of Air Quality Implementation Plans; Indiana; Maintenance Plan Update... (United States)


    ....S. Environmental Protection Agency, 77 West Jackson Boulevard, Chicago, Illinois 60604. 5. Hand.... Environmental Protection Agency, 77 West Jackson Boulevard, Chicago, Illinois 60604. Such deliveries are only.... FOR FURTHER INFORMATION CONTACT: Michael Leslie, Environmental Engineer, Control Strategies Section...

  10. An overview of the prevalence and distribution of gastrointestinal ...

    African Journals Online (AJOL)

    An overview of the prevalence and distribution of gastrointestinal parasitic infections in post-war Iraq. Noor Abdulhaleem, Aliyu Mahmuda, Al-Zihiry Khalid Jameel Khadim, Roslaini Abd Majid, Leslie Than Thian Lung, Wan Omar Abdullah, Zasmy Unyah ...

  11. Moral Action in Everyday Life: An Ethics Process to Foster Interest & Determination in the Workplace


    Sekerka, Leslie E.


    Business Ethics in a Global World: China, India, and Beyond - Santa Clara University -March 10, 2006 - Leslie E. Sekerka, Ph.D.Assistant Professor, Organizational Behavior & EthicsNaval Postgraduate School Monterey, CA

  12. 78 FR 50358 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Rule, Standards... (United States)


    ... Escherichia. coli exceedance of the proposed standard occurred during 5 percent of the monitoring period with.../2013/5079/SIR2013-5079.pdf . Accessed July 30, 2013. Dated: August 13, 2013. Leslie Kux, Assistant...

  13. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Spanish Washington Support Group Leslie of Stone Mountain, ... Providers Acoustic Neuroma Association Donate Now Newly Diagnosed What is AN? Request a Patient Kit Treatment Options Get Support Find a Provider Discussion Forum ...

  14. Fate of sulphate removed during the treatment of circumneutral mine water and acid mine drainage with coal fly ash: Modelling and experimental approach

    CSIR Research Space (South Africa)

    Madzivire, G


    Full Text Available Godfrey Madzivirea, , Wilson M. Gitarib, V.R. Kumar Vadapallic, Tunde V. Ojumud, Leslie F. Petrika a Environmental & Nano Sciences Research Group, Chemistry Department, University of the Western Cape, Modderdam Road, Private Bag X17, Bellville, 7535...

  15. 76 FR 58277 - Animal Generic Drug User Fee Act; Public Meeting; Request for Comments (United States)


    ... support for lower-cost alternatives to brand drugs for consumers. Under AGDUFA, FDA agreed to meet review... Parklawn Dr., Element Bldg., Rockville, MD 20857. Dated: September 13, 2011. Leslie Kux, Acting Assistant...

  16. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Injury Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD ... Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, Physical ...

  17. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... Injury Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD ... Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, Physical ...

  18. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... Injury Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD ... Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, Physical ...

  19. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... Injury Diane M. Rowles, MS, NP How Family Life Changes After Spinal Cord Injury Nancy Rosenberg, PsyD ... Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, Physical ...

  20. Untitled

    African Journals Online (AJOL)

    BW) ..... 2nd Edition. Leslie, H., Frank ... biochemical changes in human and animal ... (2001): Indigenous genetic resources: A Trypanosoma brucei and H. contortus infection sustainable ... Inventory and Management Limited 12 pp. SHAIB, B.

  1. Dynamical systems and linear algebra


    Colonius, Fritz (Prof.)


    Dynamical systems and linear algebra / F. Colonius, W. Kliemann. - In: Handbook of linear algebra / ed. by Leslie Hogben. - Boca Raton : Chapman & Hall/CRC, 2007. - S. 56,1-56,22. - (Discrete mathematics and its applications)

  2. Muusika valib Tristan Priimägi / Tristan Priimägi

    Index Scriptorium Estoniae

    Priimägi, Tristan, 1976-


    Heliplaatidest: Zinc & Friction "Bingo Sessions Volume 1", DJ Marky & XRS "In Rotation", Various Artists "Weapons of Mass Creation", Gilles Peterson "Worldwide Exclusives", Various Artists "Blue Note Revisited", Leslie Da Bass "Touch"

  3. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  4. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  5. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  6. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  7. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... Adult Injuries Spinal Cord Injury 101 David Chen, MD Preventing Pressure Sores Mary Zeigler, MS Transition from ... Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa ...

  8. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... Adult Injuries Spinal Cord Injury 101 David Chen, MD Preventing Pressure Sores Mary Zeigler, MS Transition from ... Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa ...

  9. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Adult Injuries Spinal Cord Injury 101 David Chen, MD Preventing Pressure Sores Mary Zeigler, MS Transition from ... Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa ...

  10. Comments to a polar bear population model


    Øritsland, Nils Are


    Larsen, T. & Ugland, K. I. (Polar Research 2 n.s., 117-118) note correctly that a Leslie matrix model treats cubs and females as independent units which is not the case for polar bears. Population projections using the Leslie model with hunting mortalities added are instructive first approximations in evaluations of field data, however, and are recommended as exercises also for polar bear biologists. An APL programme for such projections is available.

  11. 理論生態学の環境毒性データ解析への応用


    田中, 嘉成


    Ecological theories relevant to estimate hazard of chemical exposure to populational proliferation are reviewed. The Leslie matrix model describes dynamics of age or stage-structured populations under stochastic environments. If toxicants' effects are different between ages or stages of test organisms, and the chemical exposure to environments is time-dependent, the Leslie matrix model is the most straightforward method to simulate population dynamics and extinction. The life-cycle sensitivit...

  12. Summary Robert Noyce and the invention of Silicon Valley

    CERN Document Server


    This work offers a summary of the book "THE MAN BEHIND THE MICROCHIP: Robert Noyce and the Invention of Silicon Valley""by Leslie Berlin.The Man behind the Microchip is Leslie Berlin's first book. This author is project historian for the Silicon Valley Archives, a division of the Stanford University Department of Special Collections. This book tells the story of a giant of the high-tech industry: the multimillionaire Bob Noyce. This co-founder of Fairchild Semiconductor and Intel co-invented the integrated circuit which became the electronic heart of every modern computer, automobile, advance

  13. Making the "Invisible Hand" Visible: The Case for Dialogue about Academic Capitalism. (United States)

    Awbery, Susan M.

    A quiet revolution is in the process of changing academe. This revolution has been termed "academic capitalism" by S. Slaughter and L. Leslie (1997). Their ideas are the springboard for a discussion of the need for a systemic view of change in postsecondary education and why all members of the academic community should become involved in the…

  14. Eagle Hill, Kenya: changes over 60 years | Thomsett | Scopus ...

    African Journals Online (AJOL)

    Eagle Hill, the study site of the late Leslie Brown, was first surveyed over 60 years ago in 1948. The demise of its eagle population was near-complete less than 50 years later, but significantly, the majority of these losses occurred in the space of a few years in the late 1970s. Unfortunately, human densities and land use ...

  15. Commentary on "Research in Secondary English, 1912-2011: Historical Continuities and Discontinuities in the NCTE Imprint" (United States)

    Hillocks, George, Jr.


    Jory Brass and Leslie David Burns provide a useful and informative review of research appearing in the "English Journal" ("EJ") and "Research in the Teaching of English" ("RTE") over the past 100 years. It is a bit unfortunate, if understandable, to exclude books and articles in other journals, because such a restriction excludes many pieces of…

  16. Medical Surveillance Monthly Report. Volume 23, Number 1, January 2016 (United States)


    exercise and counseling decrease absenteeism due to low back pain in young conscripts: a randomized, population-based primary prevention study. Spine...MD, MPH Leslie L. Clark, PhD, MS Managing/ Production Editor Elizabeth J. Lohr, MA Layout/Design Darrell Olson Data Analysis Stephen B. Taubman, PhD

  17. An Analysis of Air Force Management of Turbine Engine Monitoring Systems (TEMS). (United States)


    Without their candid insights, this study could not have been completed. The guidance and patience of our thesis chairman, Major Leslie Zambo , whose...its own problems and looking at own piece of the pie . 2. No integration/standardization between TEMS programs. 3. Need better organizational

  18. The Complex Relations between the Academy and Industry: Views from the Literature. (United States)

    Anderson, Melissa S.


    This report on university-industry relations and their effects on higher education is based on three recently published books: Slaughter and Leslie's "Academic Capitalism"; Etzkowitz, Webster, and Healey's "Capitalizing Knowledge"; and Tudiver's "Universities for Sale." It reviews the implications of fundamental changes in the nature of…

  19. Medicare Update: Annual Wellness Visit (United States)

    ... counseling services or programs, designed to reduce risk factors, such as for weight loss, smoking cessation, fall prevention, and nutrition. • Review of the responses to the Health Risk Assessment Prepared by Leslie Fried, Alzheimer’s Association Medicare Advocacy Project. Rev. Feb 1, 2012 ...

  20. The case of Cirque du Soleil Dralion

    African Journals Online (AJOL)

    Cirque entered this landscape not by competing with the traditional circus, but by redefining it altogether (Leslie ... Amidst the decline in traditional travelling circuses in South Africa, the popularity of sold-out Cirque du Soleil ... about their motives in order to devise effective marketing strategies. Swanson, Davis and Zhao ...

  1. Alcohol Use and Alcohol-Related Problems Before and After Military Combat Deployment (United States)


    of 3000 obstetric -gynecologic pa- tients: the PRIME-MD Patient Health Questionnaire Obstetrics -Gynecology Study. Am J Obstet Gynecol. 2000;183(3):759...Shepherd J, Irish M, Scully C, Leslie I. Alcohol con- sumption among victims of violence and among com- parable UK populations. Br J Addict. 1989;84(9

  2. A way out of the wasteland. (United States)

    Koppel, G


    This essay describes the author's experiences with Judaism, with the art of Jane Austen, and with the thought of a radical Catholic theologian, Leslie Dewart. The author's synthesis of these disparate elements indicates that it is possible to achieve a religious view that satisfies one's spiritual and emotional needs without conflicting with the widespread modern conception of the integrity and openness of man's evolution.

  3. 78 FR 13395 - Federal Aviation Administration (United States)


    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of Draft...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of availability and request for comments... 4. U.S. Mail: Leslie Grey--AAL-614, Federal Aviation Administration, Airports Division, 222 West 7th...

  4. "The Other within": Race/Gender Disruptions to the Professional Learning of White Educational Leaders (United States)

    Blackmore, Jill


    Leslie Roman states "white is a colour too". Yet the whiteness of educational leaders is rarely questioned, although masculinism--enduring capacity of different masculinities to remain the norm in leadership--is increasingly under scrutiny. Rarely do white men or women leaders question their whiteness, whereas indigenous and other minority groups,…

  5. Šoti narkoparunite viis aastat kestnud saaga sai kohtus lõpu / Rasmus Kagge

    Index Scriptorium Estoniae

    Kagge, Rasmus, 1977-


    Tallinna linnakohus karistas Šoti ärimehi Robert Bruce Wright'i ja Leslie Brown'i, kes üritasid ausa äri kattevarjus rajada läbi Eesti kulgevat narkokanalit, ligi viie aasta pikkuse vangistusega. Kuna ärimehed on alates 2001. aastast viibinud Šotimaal eeluurimise all, pääsesid nad kohe vabadusse

  6. Revisiting Academic Capitalism in Canada: No Longer the Exception (United States)

    Metcalfe, Amy Scott


    In "Academic Capitalism: Politics, Policies, and the Entrepreneurial University" (1997), Slaughter and Leslie found that Canada showed signs of resisting academic capitalism. Changes in postsecondary education funding policies and the emergence of new commercialization initiatives are evidence that Canada is certainly no longer, and…

  7. Swords into ploughshares; A glimpse of solar technologies in the Soviet Union

    Energy Technology Data Exchange (ETDEWEB)

    Jesch, L.


    SAWIE Editor Leslie Jesch was invited to address a Seminar on Renewable Energies held in the Crimea in October 1990. This gave him the opportunity of a fascinating glimpse of the Soviet Union (or disUnion, as he found it.) and the chance to see the status of work in solar energy. He reports below on some of his experiences. (author).

  8. South African Journal of Surgery - Vol 43, No 1 (2005)

    African Journals Online (AJOL)

    Blunt injury of the infrarenal inferior vena cava — imaging and conservative management · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ian C Duncan, Basil J Sher, Leslie M Fingleson, 20-21 ...

  9. Blunt injury of the infrarenal inferior vena cava — imaging and ...

    African Journals Online (AJOL)

    Blunt injury of the infrarenal inferior vena cava — imaging and conservative management. Ian C Duncan, Basil J Sher, Leslie M Fingleson. Abstract. Isolated rupture of the infrarenal segment of the inferior vena cava due to blunt trauma is relatively rare. It may be missed clinically and even diagnostic peritoneal lavage may ...

  10. 78 FR 60956 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Notice of Filing of... (United States)


    ... 19, 2013 (``BDA Letter''); Leslie M. Norwood, Managing Director and Associate General Counsel, SIFMA... orders.\\49\\ \\48\\ See BDA Letter at 2. \\49\\ MSRB Letter at 4. 3. Representations by Dealers Required by... periods where retail orders are given priority over other orders, as described above.\\52\\ \\50\\ See BDA...

  11. The Relationship between the Employment of Part-Time Faculty and Student Degree and/or Certificate Completion in Two-Year Community Colleges (United States)

    Yu, Hongwei; Campbell, Dale; Mendoza, Pilar


    Prior research studies associated the employment of part-time faculty with student degree and/or certificate completion (Benjamin, 2002; Ehrenberg & Zhang, 2005; Jacoby, 2006; Leslie & Gappa, 2002; Umbach, 2008; Umbach & Wawrzynski, 2005). To date, institutional-level data have been utilized to investigate whether such employment…

  12. Red to Green or Fast to Slow? Infants' Visual Working Memory for "Just Salient Differences" (United States)

    Kaldy, Zsuzsa; Blaser, Erik


    In this study, 6-month-old infants' visual working memory for a static feature (color) and a dynamic feature (rotational motion) was compared. Comparing infants' use of different features can only be done properly if experimental manipulations to those features are equally salient (Kaldy & Blaser, 2009; Kaldy, Blaser, & Leslie,…

  13. 78 FR 79449 - Information Collection Being Reviewed by the Federal Communications Commission Under Delegated... (United States)


    ... submit your PRA comments by email, send them to: [email protected] . FOR FURTHER INFORMATION CONTACT: Leslie F... Video Relay Service and Internet-Protocol (IP) Relay providers of the following TRS mandatory minimum..., published at 72 FR 6960, February 14, 2007. The ruling applied several of the waivers to IP captioned...

  14. The National Guard in War: An Historical Analysis of the 27th Infantry Division (New York National Guard) in World War 2 (United States)


    1935. McNair, Leslie J., memorandun dated 12 July 1944, subject: "Recommendations on the Post-War National GuLard". Millet , Allan R., Semper...Moenk, Jean R., A History of Large Scale Maneuvers in the US. 1933-1964, (Ft Monroe, VA: HQ, CONARC, 1969). Moskin, J. Robert, The US Marine Corps

  15. Paroodiafilmitööstuse hambad on nüriks kulunud / Laurence Boyce

    Index Scriptorium Estoniae

    Boyce, Laurence


    Paroodiafilmidest kui filmižanrist, kultusfilmideks tõusnud "Airplane!" (USA 1980), "Airplane II: The Sequel" (USA 1982), "Palja relvaga" ("The Naked Gun" I, II, III, USA 1988-1994), peaosades Leslie Nielsen. Tänapäeva paroodiafilmid on suunatud peamiselt teismelisele kinopublikule

  16. South African Medical Journal - Vol 95, No 10 (2005)

    African Journals Online (AJOL)

    The Draft Charter of the Private and Public Health Sectors of the Republic of South Africa : health for all, or profits for few? EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Louis Reynolds, Leslie London, David Sanders, 742-743 ...

  17. On a boom and bust year class cycle

    NARCIS (Netherlands)

    Diekmann, Odo; Davydova, Natalia; van Gils, Stephanus A.


    We motivate and describe a class of nonlinear Leslie matrix models for semelparous populations, like cicadas and Pacific salmon. We then focus on a Cushing-inspired special case for which one can show rigorously that a heteroclinic boundary cycle exists and attracts nearby orbits for a certain range

  18. Sparks sädeleb Rabarocki öös. Ettevaatust! Eliidi rünnak. Hu? Hu da hell?

    Index Scriptorium Estoniae


    Ameerika ansamblist Sparks. Vaiko Eplik & Eliit heliplaatidest "1: Aastaajad", "2: Aastaajad" ja "3: Kosmoseodüsseia", esinemisest festivalil Rabarock. Hannaliisa Uusma, Leslie Da Bassi ja DJ Criticali projektist HU?, singlitest "Kosmos" ja "Absoluutselt" (Rabarockil esitusel materjal HU? debüütalbumilt "Film")

  19. Hybrid Warfare: Preparing for Future Conflict (United States)

    2015-02-17 Brown , Col Leslie F. “Twenty-First Century Warfare Will be Hybrid.” Carlisle Barracks, PA...Lebanon and Gaza.” Rand Corporation Occasional Paper. Santa Monica, CA: Rand Corporation, 2010. Jones, Gareth and Darya Korsunskaya. “U.S., EU

  20. Make it Well Done (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    In today’s fast-paced society, microwave meals are a staple of American diets. An outbreak of Salmonella, caused by an undercooked frozen meal, is a harsh reminder to carefully follow all cooking instructions. In this podcast, Leslie Hausman discusses the importance of thoroughly cooking all food before eating..

  1. 76 FR 46234 - Endangered and Threatened Wildlife and Plants; Designation of Critical Habitat for Nine Bexar... (United States)


    .... Public Hearing: We will hold a public hearing on August 17, 2011, at the Casa Helotes Senior Citizen... Helotes Senior Citizen Center, 12070 Leslie Road, Helotes, Texas 78023. People needing reasonable... designation are between $1.62 million to $35.6 million ($153,000 to $3,360,000 on an annualized basis) over 20...

  2. Last Research Board Meeting for Leon Van Hove

    CERN Multimedia

    CERN PhotoLab


    Leon Van Hove chaired the meeting for the last time, the end of the year being also the end of his term as Research Director General. The place was as usual the 6th floor conference room at the Main Building. The photo shows Sergio Fubini, Claude Bovet, Erwin Gabathuler, Volker Soergel, Leslie Camilleri, Jurg May, Mike Crowley-Milling

  3. 76 FR 73649 - Agency Information Collection Activities: Submission for OMB Review; Comment Request (United States)


    ... policy questions regarding this collection contact Leslie Jones at (410) 786-6599. For all other issues... reporting requirements for hospices, as set forth in the proposed Hospice Wage Index for Fiscal Year 2012.... Martique Jones, Director, Regulations Development Group, Division B, Office of Strategic Operations and...

  4. Disease: H00755 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00755 Acrokeratosis verruciformis Acrokeratosis verruciformis is a rare autosomal...S, Dode L, Leslie N, Sakuntabhai A, MacSween R, Saihan E, Hovnanian A ... TITLE ... Acrokeratosis verruciformi...16150218 (description) ... AUTHORS ... Rallis E, Economidi A, Papadakis P, Verros C ... TITLE ... Acrokeratosis ve

  5. Marketing the Program. New Directions for Community Colleges, Number 36. (United States)

    Keim, William A., Ed.; Keim, Marybelle C., Ed.


    This collection of essays examines the role of marketing in the recruitment and retention of community college students. First, Philip Kotler and Leslie A. Goldgehn define the marketing process and assess its potential benefits. Richard C. Richardson, Jr., and Donald S. Doucette question the effectiveness of marketing in the community college.…

  6. Biological Applications in the Mathematics Curriculum (United States)

    Marland, Eric; Palmer, Katrina M.; Salinas, Rene A.


    In this article we provide two detailed examples of how we incorporate biological examples into two mathematics courses: Linear Algebra and Ordinary Differential Equations. We use Leslie matrix models to demonstrate the biological properties of eigenvalues and eigenvectors. For Ordinary Differential Equations, we show how using a logistic growth…

  7. Mark Twain: A Collection of Critical Essays. Twentieth Century Views Series. (United States)

    Smith, Henry Nash, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Henry Nash Smith, Van Wyck Brooks, Maurice Le Breton, Kenneth Lynn, Leo Marx, Walter Blair, Daniel G. Hoffman, W. H. Auden, James M. Cox, Leslie Fiedler, Bernard DeVoto, and Tony Tanner--all dealing with the biography and…

  8. A New Observational Strategy for Monitoring the Tropical Cyclone Outflow Layer and its Relationship to Intensity and Structure Change (United States)


    vertical structure of outflow layer jets for Hurricanes Leslie and Nadine in 2012 and Invest 97L in 2013 has been conducted using NCAR- EOL /Vaisala mini...generation of dropsonde, the Yankee, Inc HDSS and XDD sonde was intercompared during CIRPAS Twin Otter test flights on 24-25 June, 2011 with NCAR- EOL

  9. Ameeriklased arvavad / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017


    Refereeritakse välismaal ilmunud arvustusi eesti komöödiafilmi "Vanad ja kobedad saavad jalad alla" : Leslie Felperini arvustus Ameerika filmitööstuse ajakirjas "Variety" (15.12.2003) ja Harper Barnesi oma USA Missouri osariigi St. Louisi ajalehes "St. Louis Post Dispatch"

  10. Structure, Function and Diversity of the Healthy Human Microbiome (United States)


    Durbin, R. Fast and accurate long-read alignment with Burrows –Wheeler transform. Bioinformatics 26, 589–595 (2010). 26. Giannoukos, G. et al...Feldgarden2, Victor M. Felix7, Sheila Fisher2, Anthony A. Fodor41, Larry J. Forney42, Leslie Foster6, Valentina Di Francesco19, Jonathan Friedman43

  11. Niigugim Qalgadangis (Atkan Food). (United States)

    Dirks, Moses; Dirks, Lydia

    A history of food gathering and food preparation techniques of Alaska natives on Atka Island in the Aleutians are presented in Western Aleut and English with illustrations by J. Leslie Boffa and Mike Dirks. Directions are given for preparing: various plants, including wild rice; salted, dried, or smoked fish; baked flour; fried dough; boiled…

  12. Science Scholars Program (United States)


    Recherche Scientifique, France The Absolute Galois Group from a Geometric Viewpoint LESLIE C SHAW Fellow (Anthropology and Archaeology ) University of...Massachusetts it Boston The Emergence of Inequality in the Maya Lowlands PATRICIA L. SIPE Fellow (Mathematics) Smith College DES and Risk

  13. Libya: Background and U.S. Relations (United States)


    designs or enrichment equipment disclosed by Libya. Leslie Lopez, “Libyans Got Nuclear Training at Malaysian Company, Police Say,” Wall Street Journal... taxation , development, and constitutional issues. In 1963, King Idris replaced the federal system of government with a unitary monarchy that centralized

  14. Hemingway; A Collection of Critical Essays. Twentieth Century Views Series. (United States)

    Weeks, Robert P., Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Lillian Ross, Malcolm Crowley, E.M. Halliday, Harry Levin, Leslie Fiedler, D.H. Lawrence, Philip Young, Sean O'Faolain, Cleanth Brooks and Robert Penn Warren, Carlos Baker, Mark Spilka, Ray B. West, Jr., Nemi D'Agostino,…


    African Journals Online (AJOL)

    by Simon Templar, "The Shlnt", created by Leslie Charteris in his novels. In this ... Kalikanyani (note the similar sounding names) is born from a picture the father ... plot depends on how Bimbo outwits some criminals who want to kill him and ...

  16. 77 FR 38305 - Guidance for Industry on Lupus Nephritis Caused by Systemic Lupus Erythematosus-Developing... (United States)


    ...] Guidance for Industry on Lupus Nephritis Caused by Systemic Lupus Erythematosus--Developing Medical... ``Lupus Nephritis Caused By Systemic Lupus Erythematosus--Developing Medical Products for Treatment... of medical products for the treatment of lupus nephritis. Dated: June 22, 2012. Leslie Kux, Assistant...

  17. Guidelines for Undergraduate Exercise Physiology in a Physical Education Teacher Education Program. Guidance Document (United States)

    National Association for Sport and Physical Education, 2006


    A course in Exercise Physiology is a common requirement among undergraduate students preparing for a career in physical education, adult fitness, or athletic training. Often, such courses are taught to an assortment of students from a variety of disciplines (Van Donselaar & Leslie, 1990) with an emphasis on physiological principles applied to…

  18. 75 FR 77645 - Agency Information Collection Activities; Proposed Collection; Comment Request; Color Additive... (United States)


    ... tracing the disposal of a certified batch or a batch that has been denied certification for noncompliance.... FDA's Web-based color certification information system allows certifiers to request color... reduction in the hour burden for reporting from use of the Web-based system. Dated: December 8, 2010. Leslie...

  19. Domain-General Contributions to Social Reasoning: Theory of Mind and Deontic Reasoning Re-Explored (United States)

    McKinnon, Margaret C.; Moscovitch, Morris


    Using older adults and dual-task interference, we examined performance on two social reasoning tasks: theory of mind (ToM) tasks and versions of the deontic selection task involving social contracts and hazardous conditions. In line with performance accounts of social reasoning (Leslie, Friedman, & German, 2004), evidence from both aging and the…

  20. Texas Hold Him (United States)

    Pohl, Robert J.


    On September 15, 2009, faculty members from four of the five community colleges in San Antonio delivered an overwhelming vote of no confidence in Chancellor Bruce H. Leslie to the Alamo Community College District's board of trustees. (One college, Northeast Lakeview, didn't participate in the vote because the college is not yet accredited.)…

  1. Proposed Sizewell 'B' nuclear power station

    Energy Technology Data Exchange (ETDEWEB)


    A report by the County Planning Officer is presented. The site history and planning policies, consultations and publicity, environmental impact, safety and national energy policy are considered. Twelve appendices cover various topics, including various representations, and a report on safety by Professor D C Leslie, the Technical Adviser to the Councils. (UK).

  2. Siim Nestor soovitab : Sports Cabaret. Ans. Flirt. DJ Krii / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-


    29. nov. Tartus Club-Tallinnas toimuvast üritusest Sports Cabaret. 4. dets. klubis BonBon projekt-ansambli Flirt (koosseisus Raul Saaremets, Andres Peets, Sten Sheripov, Leslie Laasner) kontserdist. 29. nov. Von Krahlis toimuvast hip-hop peost Check One, Two, kus esinejaks läti diskor Krii

  3. Light-effect transistor (LET) with multiple independent gating controls for optical logic gates and optical amplification (United States)

    Marmon, Jason; Rai, Satish; Wang, Kai; Zhou, Weilie; Zhang, Yong

    The pathway for CMOS technology beyond the 5-nm technology node remains unclear for both physical and technological reasons. A new transistor paradigm is required. A LET (Marmon et. al., Front. Phys. 2016, 4, No. 8) offers electronic-optical hybridization at the component level, and is capable of continuing Moore's law to the quantum scale. A LET overcomes a FET's fabrication complexity, e.g., physical gate and doping, by employing optical gating and photoconductivity, while multiple independent, optical gates readily realize unique functionalities. We report LET device characteristics and novel digital and analog applications, such as optical logic gates and optical amplification. Prototype CdSe-nanowire-based LETs, incorporating an M-S-M structure, show output and transfer characteristics resembling advanced FETs, e.g., on/off ratios up to 106 with a source-drain voltage of 1.43V, gate-power of 260nW, and a subthreshold swing of 0.3nW/decade (excluding losses). A LET has potential for high-switching (THz) speeds and extremely low-switching energies (aJ) in the ballistic transport region. Our work offers new electronic-optical integration strategies for high speed and low energy computing approaches, which could potentially be extended to other materials and devices.

  4. Another donation of computer equipment

    CERN Multimedia

    Anaïs Schaeffer


    On Thursday 27 February, CERN was pleased to donate computer equipment to a physics institute in the Philippines.   H.E. Leslie J. Baja and Rolf Heuer. Following donations of computer equipment to institutes in Morocco, Ghana, Bulgaria, Serbia and Egypt, CERN is to send 50 servers and 4 network switches to the National Institute of Physics at the University of the Philippines Diliman. CERN’s Director-General Rolf Heuer and the Ambassador of the Philippines to Switzerland and Lichtenstein, H.E. Leslie J. Baja, spoke of their enthusiasm for the project during an official ceremony. The equipment will be used for various high energy physics research programmes in the Philippines and for the University’s development of digital resources for science.

  5. Cognitive and Neural Correlates of Aging in Autism Spectrum Disorder (United States)


    this study. B. Blair Braden, PhD has been active in all of our projects on ASD and aging . She came to the lab after graduate training in...i. Aging in Autism Special Interest Group, International Society for Autism Research (INSAR). Both Drs. Baxter and Braden actively participated...AWARD NUMBER: W81XWH-15-1-0211 TITLE: Cognitive and Neural Correlates of Aging in Autism Spectrum Disorder PRINCIPAL INVESTIGATOR: Leslie C

  6. Digital storytelling: Una narrazione digitale, una documentazione visuale


    de Maurissens, Isabel


    The stories can be defined as “blended telling stories with digital technology” (Ohler, 2007). It is this blended characteristic which makes it a valid learning instrument, because it unites the story telling with the available technology. Leslie Rule defines digital storytelling as the modern equivalent of the court jester or the troubadour. Because it is used a lot in education, the article looks at the educational value of the digital tales and describes some e-communities that have be...

  7. Equipment and Tracking Test Results for the NRL Ship-to- Ship DF Laser Transmission Experiment. (United States)


    neutralize the hydrofluoric acid exhaust before it encounters the pump. We normally change the pump oil after each day of use for preventive maintenance...range, when the beacon was placed on the roof of a building 208 meters away, the GaAs signal was too weak to acquire the lock. As substantiated by the...gave a brief introduction as to why we were there. D. Leslie gave a 20-minute vugraph presentation showing some history and details of our project

  8. Medical Surveillance Monthly Report (United States)


    symptoms, health care visits, and absenteeism among Iraq War veterans. Am J Psychiatry. 2007;164(1):150–153. 20. Stein M, McAllister TW. Exploring the...complementary and alternative medicine (CAM), are terms used to describe a diverse group of practices and products with a history of use or origins outside...Contributing Editors John F. Brundage, MD, MPH Leslie L. Clark, PhD, MS Writer/Editor Valerie F. Williams, MA, MS Managing/ Production Editor Elizabeth J


    Energy Technology Data Exchange (ETDEWEB)

    Cady, K. B.; MacVean, C. R.


    A simple formulation of polyenergetic thermal utilization theory for heterogeneous lattices is proposed. The main ideas are those of Leslie, who postulated an infinite moderator region with a fictitious, energy dependent absorption which includes all heterogeneous properties of the lattice, and those of Amouyal, Benoist, and Horowitz who postulated absorption rates in terms of fuel and moderator escape probabilities. Simple approximations to energy dependent escape probabilities are discussed and lattice spectra are calculated for several light water lattices. (auth)

  10. BMC Medicine: a decade of open access medical research. (United States)

    Alam, Sabina; Patel, Jigisha


    On 24 November 2003, BMC Medicine published its first article. Ten years and over 900 articles later we look back at some of the most notable milestones for the journal and discuss advances and innovations in medicine over the last decade. Our editorial board members, Leslie Biesecker, Thomas Powles, Chris Del Mar, Robert Snow and David Moher, also comment on the changes they expect to see in their fields over the coming years.

  11. Disposal of radioactive wastes

    Energy Technology Data Exchange (ETDEWEB)



    A discussion on the disposal of radioactive wastes was held in Vienna on 20 September 1960. The three scientists who participated in the discussion were Mr. Harry Brynielsson (Sweden), Head of the Swedish Atomic Energy Company; Mr. H. J. Dunster (United Kingdom), Health Physics Adviser to the United Kingdom Atomic Energy Authority; and Mr. Leslie Silverman (United States), Professor of Harvard University, and Chairman of the US AEC Advisory Committee on Reactor Safeguards, as well as consultant on air cleaning

  12. Neoplasms of the Stomach, Liver & Pancreas: Prevention, Diagnosis, and Treatment among High-Risk Populations | Division of Cancer Prevention (United States)

    Agenda - Day 1, September 18, 2015 08:00 am - Registration 08:30 am - Welcome remarks and overview of the Conference Dr. Leslie Ford (NCI) – 5 min Dr. Edgar Colon (RCM and UPRCCC) - 5 min Luz Maria Rodriguez – Conference objectives & structure  Global Cancer Burden: An Overview and State of the Problem Moderators: Dr. Luz Maria Rodriguez and Dr. Victor Jose Carlo (PR

  13. Wave Breaking Influence in a Coupled Model of the Atmosphere-Ocean Wave Boundary Layers under Very High Wind Conditions (United States)


    PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of New South Wales,School of Mathematics,Sydney 2052, Australia, 8. PERFORMING... ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S...published, refereed] Leslie, LM, MS Speer and L. Qi, (2003): Prediction of Extreme Rainfall for the Coffs Harbour Catchment. Aust. Meteor. Mag., 52, 95

  14. Characteristics of binge eating disorder in relation to diagnostic criteria


    Wilfley, Denise E; Citrome, Leslie; Herman, Barry K


    Denise E Wilfley,1 Leslie Citrome,2 Barry K Herman3 1Department of Psychiatry, Washington University School of Medicine, St Louis, MO, 2Department of Psychiatry & Behavioral Sciences, New York Medical College, Valhalla, NY, 3Global Medical Affairs, Shire, Lexington, MA, USA Abstract: The objective of this review was to examine the evidentiary basis for binge eating disorder (BED) with reference to the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (D...

  15. *Abstracts - 7th IN-CAM Research Symposium, Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety - November 2012. (United States)

    Boon, Heather; Verhoef, Marja J


    Abstract The following are abstracts of oral and poster presentations given at the 7th IN-CAM Research Symposium - Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety, and the 4th HomeoNet Research Forum, a pre-Symposium event. The IN-CAM Research Symposium was held November 2 to 4, 2012 at the Leslie Dan Faculty of Pharmacy, University of Toronto, in Toronto, Ontario, Canada. For more information, please visit:

  16. Victoria’s Secret : a case study of maintaining brand relevance


    Ponomarenko, Polina


    Victoria’s Secret, which belongs to L Brands group, is the leading lingerie brand in its home market, US and globally, which has substantially shaped the industry of underwear in the last decades and successfully expanded into other product categories, such as swimwear, sportswear, apparel and beauty. It has been performing well financially in the resent years under the management of its CEO, Sharen Turney, who has left the brand in the beginning of 2016 and delegated to Leslie...

  17. Global low-energy weak solution and large-time behavior for the compressible flow of liquid crystals (United States)

    Wu, Guochun; Tan, Zhong


    In this paper, we consider the weak solution of the simplified Ericksen-Leslie system modeling compressible nematic liquid crystal flows in R3. When the initial data are of small energy and initial density is positive and essentially bounded, we prove the existence of a global weak solution in R3. The large-time behavior of a global weak solution is also established.

  18. Evaluation of sleep profile in schizophrenia patients treated with extended-release paliperidone: an open-label prospective study in Southeast Asia


    Kongsakon,Ronnachai; Thavichachart,Nuntika; Chung,Ka Fai; Lim,Leslie; Azucena,Beverly; Rondain,Elizabeth; Go,Benson; Costales,Fe; Nerapusee,Osot


    Ronnachai Kongsakon,1 Nuntika Thavichachart,2 Ka Fai Chung,3 Leslie Lim,4 Beverly Azucena,5 Elizabeth Rondain,6 Benson Go,7 Fe Costales,8 Osot Nerapusee9 1Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Medicine, Division of Psychiatry, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand; 3Department of Psychiatry, University of Hong Kong, Hong Kong, People’s Republic of China; ...

  19. Ekspressi tellija saab rikkaliku kogumiku Eesti muusikat

    Index Scriptorium Estoniae


    Viimasel kaheksal nädalal on ajalehemüügikohtades Eesti Ekspressi vahel olnud Eesti artistide singelplaadid: Tõnis Mägi ja Noorkuu, Jana Kask, Metsatöll, HU?, Ithaka-Maria, Rainer Jancise muusika filmist "Mina olin siin", Toe Tag, Birgit Õigemeel. Selgunud on Eesti Ekspressi tellijatele jaanuari alguses saadetava singlikogumiku lisaartistid: Vaiko Eplik, Pedigree, Traffic, Slide-Fifty ja Lenna Kuurmaa, Smilers, Leslie Da Bass ja Singer-Vinger

  20. 21st Century Military Operations in a Complex Electromagnetic Environment (United States)


    Natalie Crawford RAND Corporation RDML Jon P. Cryer, USN (ret) Northrop Grumman Mr. Stephen Cummings Raytheon Dr. Eric Evans MIT Lincoln...Heyer U.S. Navy Ms. Leslie Litton U.S. Army Dr. Charles Perkins National Reconnaissance Office Mr. Marvin Potts U.S. Air Force Dr. Stephen ...Neil Fox Virginia Tech Applied Research Corporation Ms. Hannah Freeman Strategic Analysis, Inc. Mr. Marcus Hawkins Strategic Analysis, Inc. Dr

  1. Taming the Wild West: United States Nuclear Policy (1945-1961) (United States)


    responded with her characteristic empathy “Is there anything we can do for you? For you are the one in trouble now.” 23 After all, he had only...for both the DoD and the economy. Strategic Air Command General Leslie Groves formed the original nuclear targeting board during preparation for use...prominently from a series of war games led by Eisenhower called Project Solarium. Eisenhower planned Project Solarium during conversations with

  2. Observations on the seasonal distribution of native fish in a 10-kilometer reach of San Bernardino Creek, Sonora, Mexico (United States)

    C. O. Minckley


    San Bernardino Creek is a northern tributary of the Río Yaqui that originates in the United States and crosses the International Border just east of Douglas, Arizona/Agua Prieta, Sonora and immediately south of San Bernardino/Leslie Canyon National Wildlife Refuge. Six of eight Río Yaqui native fishes occur in this reach:four minnows, a sucker, and a poeciliid....

  3. ‘‘I think that the small peptides are the best for healthy ageing…’’, an interview with Vladimir Khavinson

    DEFF Research Database (Denmark)

    Rattan, Suresh


    Since its inception in 2000, Biogerontology has published interviews with some of the most renowned and intellectually influential biogerontologists, including Len Hayflick, Robin Holliday, Denham Harman,VincentCristofalo, Claudio Franceschi, Leslie Robert, Ken Kitani, Geroge Martin, Zhores Medve...... Vladimir Khavinson talking about his life and work in Russia during and after the Soviet times, his ideas on stress and health, his discoveries of the healthy ageing promoting small peptides, and other anti-ageing interventions....

  4. Simulation of Flow for an Immersed Sphere (United States)


    manufacture , use, or sell any patented invention that may relate to them. This report was cleared for public release by the 96th Air Base Wing, Public...failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE...capability for using the Large Eddy Simulation with LInear Eddy Modeling in 3 Dimensions (LESLIE3D) multiphase physics computer program. A high Reynolds

  5. Make it Well Done (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts


    In today’s fast-paced society, microwave meals are a staple of American diets. An outbreak of Salmonella, caused by an undercooked frozen meal, is a harsh reminder to carefully follow all cooking instructions. In this podcast, Leslie Hausman discusses the importance of thoroughly cooking all food before eating..  Created: 12/5/2013 by MMWR.   Date Released: 12/5/2013.

  6. Complex dynamic behavior in a food web consisting of two preys and a predator

    International Nuclear Information System (INIS)

    Gakkhar, Sunita; Singh, Brahampal


    This paper deals with the dynamic behavior of a realistic two preys and one predator system. The predator dynamics is governed by modified Leslie Gower model. The local and global stability analysis has been carried out. Conditions for stability of planar equilibrium points and positive equilibrium points have been obtained. Numerical simulations are carried out for biologically feasible choices of parameters to display the existence of non-chaotic and quasi-periodic solution of non-linear system

  7. Recognition and Attribution of Beliefs in the Child

    Directory of Open Access Journals (Sweden)

    Dante G. Duero


    Full Text Available Empirical evidence suggests that human beings develop the capacity to ascribe mental states (as false beliefs at the age of four or five years old. This has been demonstrated through the use of different tests (appearance – reality, representational change and false belief tests. Three year old infants commit serious mistakes in such tests. Perner (1994; 1995 suggests that such capacities depend on the metacognitive skills that permits the comprehension of the mind as a representational structure. But its are not developed until the age of four or five. Leslie (1987; 1988; 1994b sustains that such capacity depends on the ontogenetic development of a “paraintentional” modular structure in the brain. Leslie think that around the second year of life children express “mentalist” abilities. For Leslie, lack of executives capacities and lack of a mechanism responsible for coordination of inferences explain the difficulties of children in false belief tests. The objective of this work is to inquire why 3 years old children can not attribute false beliefs, in “false belief test”. The data shows that children are capable of solving problems that require mental adscription at 3 years old, as long as problems are simplified. This indicates that the reported low performance of 3 year old children can be explained in terms of general skills to compute information.

  8. Medical Surveillance Monthly Report (MSMR). Volume 22, Number 3, March 2015 (United States)


    2000–2014 Francis L. O’Donnell, MD, MPH; Stephen B. Taubman, PhD; Leslie L. Clark, PhD, MS P A G E 1 7 Update: heat injuries, active component, U.S...S, Sabatini C, Tagliaferri L, Principi N. Borrelia burgdorferi infection and Lyme disease in children. IJID. 2013;17(3):e153–e158. 20. Bacon RM, Ku...Refraction and Accommodation, Active Component Service Members, U.S. Armed Forces, 2000–2014 Francis L. O’Donnell, MD, MPH; Stephen B. Taubman, PhD

  9. The Evolution and Impact of PCS Technology. (United States)


    CTIA), June, 1994), p. 4. 44 Communication Daily, Vol. 14, No. 137, July 18, 1994, p.3. i45 FinTech Mobile Communications, June 16, 1994. 46 FCC...a palm-sized portable answering machine 3 which can receive and replay voice messages based on Voice Now service being developed I 47 FinTech Mobile...1994. 66 FinTech Mobile Communications, June 16, 1994. 67 Leslie Cauley, "U S West Inc., AirTouch Plan," Wall Street Journal, July 26, 1994. I II-10

  10. The genesis of NRX - first stop on the road to CANDU

    Energy Technology Data Exchange (ETDEWEB)

    Arsenault, J.E.


    The CANDU (Canada Deuterium Uranium) reactor family is traceable to World War Two and to certain principal players. They gave Canada an early entry into the world of practical nuclear energy with the NRX (National Research Experimental) reactor, developed under the auspices of the ABC (America, Britain, Canada) countries. The principal players on the NRX project were, in alphabetical order: James Chadwick, C.D. Howe, Leslie R. Groves and C-J. Mackenzie. Their careers up to about 1940 are outlined in Section 10. (author)

  11. Identification and Characterization of Functional Domains of the Diphtheria Toxin Repressor (DtxR) (United States)


    Jobling, Leslie M. Palmer, Brenda Talley, Edda M. Twiddy, Sankaran Krishnan, for your knowledge, guidance, and friendship. My friends and colleagues...was made low-iron by the addition of an iron chelator, ethelenediamine-di-o-hydroxyphenyl acetic acid ( EDDA ) (Sigma Chemical Co., St. Louis, 500 ~gJrn1 ; and LB agar medium was made iron-deficient by adding EDDA at 40 ~gJml (Schmitt et al., 199Ib). EDDA was deferrated by the method of

  12. Geology of the Mid-Miocene Rooster Comb Caldera and Lake Owyhee Volcanic Field, eastern Oregon: Silicic volcanism associated with Grande Ronde flood basalt (United States)

    Benson, Thomas R.; Mahood, Gail A.


    The Lake Owyhee Volcanic Field (LOVF) of eastern Oregon consists of rhyolitic caldera centers and lava fields contemporaneous with and spatially related to Mid-Miocene Columbia River flood basalt volcanism. Previous studies delineated two calderas in the southeastern part of LOVF near Owyhee Reservoir, the result of eruptions of two ignimbrites, the Tuff of Leslie Gulch and the Tuff of Spring Creek. Our new interpretation is that these two map units are differentially altered parts of a single ignimbrite produced in a major phreatomagmatic eruption at 15.8 Ma. Areas previously mapped as Tuff of Spring Creek are locations where the ignimbrite contains abundant clinoptilolite ± mordenite, which made it susceptible to erosion. The resistant intracaldera Tuff of Leslie Gulch has an alteration assemblage of albite ± quartz, indicative of low-temperature hydrothermal alteration. Our new mapping of caldera lake sediments and pre- and post-caldera rhyolitic lavas and intrusions that are chemically similar to intracaldera Tuff of Leslie Gulch point to a single 20 × 25 km caldera, which we name the Rooster Comb Caldera. Erosion of the resurgently uplifted southern half of the caldera created dramatic exposures of intracaldera Tuff of Leslie Gulch cut by post-caldera rhyolite dikes and intrusions that are the deeper-level equivalents of lava domes and flows that erupted into the caldera lake preserved in exposures to the northeast. The Rooster Comb Caldera has features in common with more southerly Mid-Miocene calderas of the McDermitt Volcanic Field and High Rock Caldera Complex, including formation in a basinal setting shortly after flood basalt eruptions ceased in the region, and forming on eruption of peralkaline ignimbrite. The volcanism at Rooster Comb Caldera postdates the main activity at McDermitt and High Rock, but, like it, begins 300 ky after flood basalt volcanism begins in the area, and while flood basalts don't erupt through the silicic focus, are

  13. Review of recent publications

    Directory of Open Access Journals (Sweden)


    Full Text Available Christine Daigle. Jean-Paul Sartre by Candice Nicolas Anna Marie Sandoval. Toward a Latina Feminism of the Americas: Repression and Resistance in Chicana and Mexicana Literature by Yajaira M. Padilla Ruth Cruickshank. Fin de millénaire French Fiction: The Aesthetics of Crisis by Martine Motard-Noar Sanna Turoma. Brodsky Abroad: Empire, Tourism, Nostalgia by Galya Diment Svetlana Alexievich. Voices from Chernobyl: the Oral History of a Nuclear Disaster by Teresa Polowy Leslie Raymond Williams. A Companion to Gabriel García Márquez by David William Foster

  14. Prison Radicalization in County Jails: Disrupting Terrorist Acts Through Information Sharing (United States)


    States Attorney’s Office, March 26, 2014, cae /news/docs/2014/2014_03/03-26-14Teausant.html. 11 Leslie Holland, “California...have reached an all-time high as a result of the Public Safety Realignment Act. In the first quarter of 2014, the average daily population the ACLU, the Sheriff’s Department has recently made significant improvements regarding the treatment of Muslim inmates. Previously, other faiths

  15. Buhler, James. Neumeyer, David. Deemer, Rob. Hearing the Movies: Music and Sound in Film History

    Directory of Open Access Journals (Sweden)

    Carlos Henrique Silveira


    Full Text Available James Buhler et David Neumeyer sont certainement les auteurs les plus importants à publier sur l’analyse de la musique de film depuis les années quatre-vingt-dix aux Etats-Unis. Entre autres contributions, ils ont édité ensemble (avec Caryl Flinn Music and Cinema, un livre consacré aux différentes perspectives de l’étude de la musique de film. Tous les deux sont professeurs de théorie musicale à l’école de musique de l’université du Texas à Austin (Neumeyer étant aussi professeur à Leslie Wa...

  16. Pædagogisk arbejde med børn med autisme

    DEFF Research Database (Denmark)

    Miðskarð, Jóhannes


    concepts from traditional, stage focused theories of development such as that of Piaget and Leslie's »Theory of Mind«. The heavy emphasis on cognition is discussed and other venues of understanding are presented. Billington (2000) and Meyer (2003) maintain that autism is better understood as either......Working with autistic children, and studying psychology made the author wonder abt. the terms used to describe autism and their consequences. Adhering to Burman's definition of deconstruction (1994), he discusses the problem of trying to understand the development of the autistic child, using...

  17. Fast Multiscale Algorithms for Wave Propagation in Heterogeneous Environments (United States)


    Leslie Greengard, Thomas Hagstrom, Shidong Jiang . Extension of the Lorenz–Mie– Debye method forelectromagnetic scattering to the time-domain, Journal of...Φ ∂z +ΣΦ = 0, where Φ is a vector of length m(p+1) for a boundary condition order of p and a hyperbolic system with m independent variables. Here...exterior of a sphere. J. Comput. Phys., 274:191–207, 2014. [19] L. Greengard, T. Hagstrom, and S. Jiang. Extension of the Lorenz-Mie- Debye method for

  18. New management models in universities and in teaching work in Colombia

    Directory of Open Access Journals (Sweden)

    Omar Cabrales Salazar


    Full Text Available This article defines the theoretical foundations of organizational models that have been implemented in Colombian universities in recent years. The discussion is based on a contemporary perspective of the educational system, called Cognitive or Academic Capitalism, initially introduced by Slaughter and Leslie (1997 to call the new investigative dynamics incorporated from companies to universities, as a new valuation option of the capital represented by research and innovation, so that the generated within them, can be commercialized and susceptible to alienation more easily in the market.

  19. The physics of distributed information systems

    International Nuclear Information System (INIS)

    Aurell, Erik


    This paper aims to introduce Distributed Systems as a field where the ideas and methods of physics can potentially be applied, and to provide entry points to a wide literature. The contributions of Leslie Lamport, inspired by Relativity Theory, and of Edsger Dijkstra, which has the flavor of a growth process, are discussed at some length. The intent of the author is primarily to stimulate interest in the statistical physics community, and the discussions are therefore framed in a non-technical language; the author apologizes in advance to readers from the computer science side for the unavoidable impreciseness and ambiguities

  20. Analysis of Disaster Planning in Business and Industry (United States)


    Alternatives, 13 May 1991, 1. 13. Deegan , Joseph, and Jack Jolley. "Selling Crisis Management." Security Management Jun 1985, 50. 14. Atkin, Leslie, ed. "PG... Deegan , Joseph, and Jack Jolley. "Selling Crisis Management." Security Management Jun 1985, 50. 16. Carey, John. "Getting Business to Think About the...1985, 5. 22. Aronoff, Craig E., and John L. Ward. "Why Owners Don’t Plan." Nation’s Business Jun 1990, 59. 23. Phelps, Norman L. "Setting Up a Crisis

  1. Bibliografía



    A. LITERATURA GENERAL 1. Libros Bethell, Leslie (editora), Historia de América Latina, Varios volúmenes, Barcelona, Cambridge University Press-Editorial Crítica, 1992. Bobbio. Norberto, El futuro de la democracia, México, Fondo de Cultura Económica, 1986. —, Contribución a la teoría del derecho, Madrid, Editorial Debate, 1990. Cardoso, Fernando H. y Enzo Faletto, Dependencia y desarrollo en América Latina, México, Siglo xxi Editores, 14a. ed., 1978. Carey, John y Matthew Shugart, Presidents a...

  2. Pattern Formation in Predator-Prey Model with Delay and Cross Diffusion

    Directory of Open Access Journals (Sweden)

    Xinze Lian


    Full Text Available We consider the effect of time delay and cross diffusion on the dynamics of a modified Leslie-Gower predator-prey model incorporating a prey refuge. Based on the stability analysis, we demonstrate that delayed feedback may generate Hopf and Turing instability under some conditions, resulting in spatial patterns. One of the most interesting findings is that the model exhibits complex pattern replication: the model dynamics exhibits a delay and diffusion controlled formation growth not only to spots, stripes, and holes, but also to spiral pattern self-replication. The results indicate that time delay and cross diffusion play important roles in pattern formation.

  3. Hersendood. Mackies leibniziaanse herinterpretatie van Lockes theorie van persoonsidentiteit


    De Vleeschouwer, Gregory


    In his book, 'Problems from Locke', John Leslie Mackie presents a theory of personal identity (pi) that is meant to be a supplement and correction of Locke's pi-theory. In a first part I introduce the criterion of pi that was standard before Locke's pi-theory. By showing in a second part how Locke reacted against this traditional criterion, I show wherein the singularity of Locke's pi-theory exists. In a third part I explain how Leibniz is moved by the same solicitude as Locke, but also how h...

  4. El enfoque científico de la contabilidad como aporte al desarrollo de la economía humana a nivel internacional


    García Casella, Carlos Luis


    Para lograr una plena colaboración entre la contabilidad y la economía un aspecto importante es reconocer el enfoque científico de la contabilidad que deriva de su concepto, sus características, los términos primitivos que utiliza y sus supuestos básicos. En base a la hipótesis de existencia de segmentos contables, se concentra en el denominado contabilidad social según la definición del profesor emérito de la Universidad de Buenos Aires William Leslie Chapman. Se trata sus dos partes princi...

  5. Archeological Test Excavations at The Lake Acworth Site (9Co45) and The Butler Creek (9Co46) Sites: Two Prehistric Settlements in the Piedmont Uplands, Allatoona Lake, Cobb County, Georgia (United States)


    County, C~eorgia 54 7. AUTHOR(s) 8. CONTRACT OR GRANT NUMBER(s) J. S. Cable and L. E. Raymer , with contributions by J. H. Raymer and C. E. Cantley...Georgia 30083 John S. a. ,JohnS. Cal ... rincipal Inv estigator and Author Leslie E. Raymer - Ethnobotanist and Co-Author with contributions by John H...thank Mr. Carl Etheridge, Mr. Robert Gentry, and Mr. Ken Huddleston for their assistance and cooperation. Mr. Etheridge in particular is deserving of a

  6. Group inverses of M-matrices and their applications

    CERN Document Server

    Kirkland, Stephen J


    Group inverses for singular M-matrices are useful tools not only in matrix analysis, but also in the analysis of stochastic processes, graph theory, electrical networks, and demographic models. Group Inverses of M-Matrices and Their Applications highlights the importance and utility of the group inverses of M-matrices in several application areas. After introducing sample problems associated with Leslie matrices and stochastic matrices, the authors develop the basic algebraic and spectral properties of the group inverse of a general matrix. They then derive formulas for derivatives of matrix f

  7. Norris Bradbury and Edward Teller: A Fission-Fusion Reaction

    Energy Technology Data Exchange (ETDEWEB)

    Meade, Roger Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    On a bright, sunny day in October 1945, a boisterous and jubilant crowd assembled in front of Fuller Lodge to watch as the Army-Navy “E” Award, a prestigious national honor given for “Excellence in Production” during World War II, was presented to the Los Alamos Laboratory. Major General Leslie Groves, the commanding officer of the Manhattan Project; Navy Commodore William S. (Deak) Parsons, the wartime leader of the Laboratory’s Ordnance Division; Robert Sproul, the President of the University of California; and J. Robert Oppenheimer accepted the award on behalf of the Laboratory.

  8. Kahn jõudis Eestisse tagasi, Komendant mitte veel / Toivo Tammik

    Index Scriptorium Estoniae

    Tammik, Toivo


    Louis Kahni päevad Kuressaares 6. ja 7. X. Arhitekti tütar Alexandra Tyng kinkis Kuressaare linnale Louis Kahni portree. Philadelphia ülikooli arhiivide juhataja William Whitaker ja Ingrid Mald-Villandi korraldasid L. Kahni tööde näituse, kujundas Peeter Laurits. Kuressaare Linnateatris näidati 6. X arhitekti poja Nathaniel Kahni filmi "My architect", 7. X toimus konverents. Robert McCarteri, Anne Tyngi, Vilen Künnapu ja Thomas Leslie (L. Kahni ja August Komendandi suhted) ettekannetest

  9. The Coast Artillery Journal. Volume 76, Number 5, September-October 1933 (United States)


    hindering such endeavor are lack of motive, lack of self-confidence, resentment, and fear or likelihood of personal sacrifice. These barren primary...between the Balkans and the Far East." At Plymouth there is a mockbattle between a "Q" boat and a submarine, the .spectators occupying the deck of an...52d, Fort Hancock. 2nd Lt. Robert J. Lawlor, assigned to 61st, Fort Sheridan. 2d Lt. Robert C. Leslie, to the Philip- pines for assignment, sailing New

  10. Management of patients with non-Hodgkin’s lymphoma: focus on adoptive T-cell therapy

    Directory of Open Access Journals (Sweden)

    Perna SK


    Full Text Available Serena Kimi Perna,1 Leslie E Huye,1,† Barbara Savoldo1,2 1Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital, Houston, TX, 2Department of Pediatrics, Texas Children's Hospital, Houston, TX, USA  †Leslie E Huye passed away on January 1st, 2015 Abstract: Non-Hodgkin's lymphoma (NHL represents a heterogeneous group of malignancies with high diversity in terms of biology, clinical responses, and prognosis. Standard therapy regimens produce a 5-year relative survival rate of only 69%, with the critical need to increase the treatment-success rate of this patient population presenting at diagnosis with a median age of 66 years and many comorbidities. The evidence that an impaired immune system favors the development of NHL has opened the stage for new therapeutics, and specifically for the adoptive transfer of ex vivo-expanded antigen-specific T-cells. In this review, we discuss how T-cells specific for viral-associated antigens, nonviral-associated antigens expressed by the tumor, T-cells redirected through the expression of chimeric antigen receptors, and transgenic T-cell receptors against tumor cells have been developed and used in clinical trials for the treatment of patients with NHLs. Keywords: adoptive immunotherapy, cytotoxic T lymphocytes (CTLs, chimeric antigen receptor (CAR, transgenic T-cell receptors 

  11. Possible occultation by Pluto from US East Coast (United States)

    Waagen, Elizabeth O.


    We have been asked to help disseminate the news of a possible occultation by Pluto visible to observers on the US East coast. Although the AAVSO does not ordinarily issue announcements of upcoming occultations, in this case the object is Pluto and the NASA New Horizons mission ( will be visiting Pluto in 2015. The information below has been supplied by Dr. Leslie Young (Southwest Research Institute), who is coordinating this observing campaign on Pluto. Dr. Young is also Deputy Project Scientist for the New Horizons mission. ALERT: Possible Pluto occultation Wednesday night (2012/06/14 03:28 UT) from US East coast. CONTACT: Leslie Young (; work: 303-546-6057; skype: drpluto). Also see our planning pages in progress at Pluto's thin, nitrogen atmosphere is in vapor-pressure equilibrium with the surface ice, and changes seasonally. We've seen it double since 1988, and now we measure its pressure once or twice a year. The technique we use is stellar occultation, when a star passes behind Pluto's atmosphere. The atmosphere defocuses the starlight. By the timing of the fading of the star, we measure the pressure and temperature in Pluto's atmosphere at ~10 km resolution. MORE INFORMATION: See

  12. Religion for Revolution: Shifting Perceptions of Bodily Ritual in the Lebanese Shi‘a Community

    Directory of Open Access Journals (Sweden)

    Savannah Danielle Dodd


    Full Text Available This paper applies Cartesian and Weberian theories of rationalization and Leslie Sharp’s concept of bodily commodification to the transition in the observance of Ashura from practices of bodily mortification to blood donation among the Shi‘a community in Lebanon. The author argues that this shift politicizes salvation and sacralises revolution through a process of rationalization, made possible through the invocation of the Karbala Paradigm, in order to facilitate the commodification of blood for political activism. This shift in ritual practice for the commodification of blood has occurred as a result of three key transitions: (i from body/self-unity to body/self-dualism; (ii from salvation in the next world to salvation in this world; and (iii from personal salvation to societal salvation.[Dengan merujuk teori rasionalisasi model Descartes dan Weber serta konsep komodifikasi tubuh dari Leslie Sharp, tulisan ini menelusur pergeseran yang terjadi pada ritual Ashura dari praktik melukai diri menjadi kegiatan donor darah di kalangan Syiah di Lebanon. Proses ini, menurut penulis, telah mengubah konsep penyelamatan dan revolusi sakral melalui proses rasionali­sasi. Hal ini terjadi dengan memakai Paradigma Karbala sebagai media komodifikasi darah untuk aktivisme politik. Pergeseran komodifikasi darah dalam praktik ritual ini terjadi melalui tiga transisi utama: (i dari kesatuan diri menjadi dualisme diri; (ii dari keselamatan akhirat menjadi keselamatan dunia; dan (iii dari penyelamatan pribadi menjadi penyelamatan sosial].

  13. Alcohol advertising and youth. (United States)

    Martin, Susan E; Snyder, Leslie B; Hamilton, Mark; Fleming-Milici, Fran; Slater, Michael D; Stacy, Alan; Chen, Meng-Jinn; Grube, Joel W


    This article presents the proceedings of a symposium at the 2001 Research Society on Alcoholism meeting in Montreal, Canada. The symposium was organized and chaired by Joel W. Grube. The presentations and presenters were (1) Introduction and background, by Susan E. Martin; (2) The effect of alcohol ads on youth 15-26 years old, by Leslie Snyder, Mark Hamilton, Fran Fleming-Milici, and Michael D. Slater; (3) A comparison of exposure to alcohol advertising and drinking behavior in elementary versus middle school children, by Phyllis L. Ellickson and Rebecca L. Collins; (4) USC health and advertising project: assessment study on alcohol advertisement memory and exposure, by Alan Stacy; and (5) TV beer and soft drink advertising: what young people like and what effects? by Meng-Jinn Chen and Joel W. Grube.

  14. Venus y el fin del mundo

    Directory of Open Access Journals (Sweden)

    Gonzalo Munévar


    Full Text Available Este artículo busca demostrar que los argumentos generales acerca de la exploración científica valen también para las ciencias espaciales. El trabajo se basa en el ejemplo de la exploración de Venus y lo que esta nos dice acerca de nuestro propio planeta. Argumenta que el concepto de la probabilidad de Leslie es incorrecto, como también lo son las dudas sobre la evidencia Venusiana. Así mismo, concluye que no se puede rechazar la importancia que tienen los descubrimientos inesperados que han resultado de la exploración de Venus para ayudarnos a comprender nuestro propio planeta. Y que si van a ser rechazados estos descubrimientos debe ser por razones científicas, no por intuiciones acerca de la probabilidad.

  15. Finite Time Blowup in a Realistic Food-Chain Model

    KAUST Repository

    Parshad, Rana; Ait Abderrahmane, Hamid; Upadhyay, Ranjit Kumar; Kumari, Nitu


    We investigate a realistic three-species food-chain model, with generalist top predator. The model based on a modified version of the Leslie-Gower scheme incorporates mutual interference in all the three populations and generalizes several other known models in the ecological literature. We show that the model exhibits finite time blowup in certain parameter range and for large enough initial data. This result implies that finite time blowup is possible in a large class of such three-species food-chain models. We propose a modification to the model and prove that the modified model has globally existing classical solutions, as well as a global attractor. We reconstruct the attractor using nonlinear time series analysis and show that it pssesses rich dynamics, including chaos in certain parameter regime, whilst avoiding blowup in any parameter regime. We also provide estimates on its fractal dimension as well as provide numerical simulations to visualise the spatiotemporal chaos.

  16. Rethinking the Relationship Between Academia and Industry: Qualitative Case Studies of MIT and Stanford. (United States)

    Zhu, Fengliang; Hawk, Soaring


    As knowledge has become more closely tied to economic development, the interrelationship between academia and industry has become stronger. The result has been the emergence of what Slaughter and Leslie call academic capitalism. Inevitably, tensions between academia and industry arise; however, universities such as MIT and Stanford with long traditions of industry interaction have been able to achieve a balance between academic and market values. This paper describes the strategies adopted by MIT and Stanford to achieve this balance. The results indicate that implicit culture is a stronger determinant of balance than are explicit rules. Finally, the author proposes a concept of balance to reconsider the relationship between academia and industry: today's universities, particularly those with strengths in engineering and management, are both symbiotic and interdependent with industry. A reasonable attitude toward the university-industry relationship is that of balance rather than strict separation. Universities can thus establish effective mechanisms to reach a balance between conflicting values.

  17. L’Image à Byzance. Une nouvelle lecture des textes anciens

    Directory of Open Access Journals (Sweden)

    Maria Zoubouli


    Full Text Available Thèse soutenue le 9 avril 2009Composition du juryFrançois Hartog,André Guillou,Ennio Concina,Anca Vasiliu,Léon Pressouyre,(Pré-rapporteurs : Leslie Brubaker, Ennio Concina.RésuméÀ Byzance eikon désigne indistinctement toute forme de représentation et son usage, relève de multiples régimes, conceptuels aussi bien que pratiques. Nous partons des premiers discours apologétiques issus de la crise iconoclaste pour chercher en aval, dans la littérature antérieure, la théorie byzantine de l’image, ...

  18. Investigación Crítica: Desafíos y Posibilidades

    Directory of Open Access Journals (Sweden)

    Fractalitats en Investigació Crítica


    Full Text Available The emergence of the social sciences has provided a network of technologies, knowledges, practices and discourses to regulate and govern society. The social sciences may play a central role in developing forms of social control. Modern 'knowledge societies' manage the production of scientific knowledge in a way that privileges the kind of thinking that is consistent with current hegemonic thought, and reduces the possibility of critical perspectives (Slaughter y Leslie, 1997, 2001. The social sciences are in the paradox of questioning the fundamentals of what they,in some sense, actively constitute. The development of post-fordist societies and our academic location in the belly of the beast (Haraway, 1991 prompts a reflection on the context, possibilities and forms of critical work in our present institutional circumstances. This paper considers the methodological principles and political implications of academic critical research.

  19. Building form and environmental performance: archetypes, analysis and an arid climate

    Energy Technology Data Exchange (ETDEWEB)

    Ratti, C.; Raydan, D.; Steemers, K. [Department of Architecture, The Martin Centre for Architectural and Urban Studies, University of Cambridge, Cambridge (United Kingdom)


    Leslie Martin and others at Cambridge University addressed the question 'What building forms make the best use of land?' in a number of influential papers published in the late 1960s. They selected six simplified urban arrays based on archetypal building forms. Then they analysed and compared the archetypes in terms of built potential and day lighting criteria, eventually reaching the conclusion that courtyards perform best. Their results, which inspired a generation of designers, are briefly reviewed here and reassessed in environmental terms using innovative computer analysis techniques. Furthermore, the implications of their question, which to date has not addressed the link with climate, are explored using a case study in a hot-arid region. (author)

  20. A transect through a clastic-swamp to peat swamp ecotone in the Springifled Coal, Middle Pennsylvanian age of Indiana, USA

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, T.L.; DiMichele, W.A. [University of Illinois, Urbana, IL (United States). Dept. of Plant Biology


    Permineralized fossil plants in coal balls were collected along a kilometer transect through an organic-rich shale in the Springifled Coal in southwestern Indiana. The organic shale is an upper bench of the Springfield Coal in an area where the coal is split into an upper and lower bench by a complex system of clastics that originated as a splay. The clastic wedge, described as the Folsomville Member/Leslie Cemetery paleochannel, is up to 6 km wide and 15 m thick. The transect being approximately 100 m from the edge of the clastic wedge that splits the coal seam and follows the upper bench of coal over and toward the center of the clastic wedge. The dominant elements of the vegetation were the lycopsid tree Paralycopodites brevifolius and several species of medullosan pteridosperms. This report confirms the ecotonal habitats of this vegetation.

  1. Bifurcation and Stability in a Delayed Predator-Prey Model with Mixed Functional Responses (United States)

    Yafia, R.; Aziz-Alaoui, M. A.; Merdan, H.; Tewa, J. J.


    The model analyzed in this paper is based on the model set forth by Aziz Alaoui et al. [Aziz Alaoui & Daher Okiye, 2003; Nindjin et al., 2006] with time delay, which describes the competition between the predator and prey. This model incorporates a modified version of the Leslie-Gower functional response as well as that of Beddington-DeAngelis. In this paper, we consider the model with one delay consisting of a unique nontrivial equilibrium E* and three others which are trivial. Their dynamics are studied in terms of local and global stabilities and of the description of Hopf bifurcation at E*. At the third trivial equilibrium, the existence of the Hopf bifurcation is proven as the delay (taken as a parameter of bifurcation) that crosses some critical values.

  2. The origin of life at the origin of ageing? (United States)

    Currais, Antonio


    At first glance, the ageing of unicellular organisms would appear to be different from the ageing of complex, multicellular organisms. In an attempt to describe the nature of ageing in diverse organisms, the intimate links between the origins of life and ageing are examined. Departing from Leslie Orgel's initial ideas on why organisms age, it is then discussed how the potentially detrimental events characteristic of ageing are continuous, cell-autonomous and universal to all organisms. The manifestation of these alterations relies on the balance between their production and cellular renewal. Renewal is achieved not only by repair and maintenance mechanisms but, importantly, by the process of cell division such that every time cells divide ageing-associated effects are diluted. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Red to green or fast to slow? Infants' visual working memory for "just salient differences". (United States)

    Kaldy, Zsuzsa; Blaser, Erik


    In this study, 6-month-old infants' visual working memory for a static feature (color) and a dynamic feature (rotational motion) was compared. Comparing infants' use of different features can only be done properly if experimental manipulations to those features are equally salient (Kaldy & Blaser, 2009; Kaldy, Blaser, & Leslie, 2006). The interdimensional salience mapping method was used to find two objects that each were one Just Salient Difference from a common baseline object (N = 16). These calibrated stimuli were then used in a subsequent two-alternative forced-choice preferential looking memory test (N = 28). Results showed that infants noted the color change, but not the equally salient change in rotation speed. © 2013 The Authors. Child Development © 2013 Society for Research in Child Development, Inc.

  4. Stability analysis of pest-predator interaction model with infectious disease in prey (United States)

    Suryanto, Agus; Darti, Isnani; Anam, Syaiful


    We consider an eco-epidemiological model based on a modified Leslie-Gower predator-prey model. Such eco-epidemiological model is proposed to describe the interaction between pest as the prey and its predator. We assume that the pest can be infected by a disease or pathogen and the predator only eats the susceptible prey. The dynamical properties of the model such as the existence and the stability of biologically feasible equilibria are studied. The model has six type of equilibria, but only three of them are conditionally stable. We find that the predator in this system cannot go extinct. However, the susceptible or the infective prey may disappear in the environment. To support our analytical results, we perform some numerical simulations with different scenario.

  5. Ssk or Esw? -- the Bloor-Lynch Debate Revisited (United States)

    Cheng, Kai-Yuan


    Philosophical discussions of rule-following in the later Wittgenstein (1953, 1967) are an important source of inspiration for the development of views on the social nature of scientific knowledge. Two major opposing views in this inquiry -- Bloor's sociology of scientific knowledge (SSK) (1983, 1991, 1992, 1997) and Lynch's (1992, 1993) ethnomethodological studies of work (ESW) -- represent two positions derived from two different readings of Wittgenstein's later writings on rule-following. The aim of this paper is two-fold. One is to re-examine the noted Bloor-Lynch debate by considering Kusch's (2004) recent discussion of this debate. Another is to show that a new semantic framework of rule-following ascriptions based on a cognitive approach to the study of generics can be provided such that SSK and ESW are compatible in it (Leslie, 2009; Cheng, 2011).

  6. Fractional Response Models - A Replication Exercise of Papke and Wooldridge (1996

    Directory of Open Access Journals (Sweden)

    Harald Oberhofer


    Full Text Available This paper replicates the estimates of a fractional response model for share data reported in the seminal paper of Leslie E. Papke and Jeffrey M. Wooldridge published in the Journal of Applied Econometrics 11(6, 1996, pp.619-632. We have been able to replicate all of the reported estimation results concerning the determinants of employee participation rates in 401(k pension plans using the standard routines provided in Stata. As an alternative, we estimate a two-part model that is capable of coping with the excessive number of boundary values equalling one in the data. The estimated marginal effects are similar to those derived in the paper. A small-scale Monte Carlo simulation exercise suggests that the RESET tests proposed by Papke and Wooldridge in their robust form are useful for detecting neglected non-linearities in small samples.

  7. Correcting a Persistent Manhattan Project Statistical Error (United States)

    Reed, Cameron


    In his 1987 autobiography, Major-General Kenneth Nichols, who served as the Manhattan Project's ``District Engineer'' under General Leslie Groves, related that when the Clinton Engineer Works at Oak Ridge, TN, was completed it was consuming nearly one-seventh (~ 14%) of the electric power being generated in the United States. This statement has been reiterated in several editions of a Department of Energy publication on the Manhattan Project. This remarkable claim has been checked against power generation and consumption figures available in Manhattan Engineer District documents, Tennessee Valley Authority records, and historical editions of the Statistical Abstract of the United States. The correct figure is closer to 0.9% of national generation. A speculation will be made as to the origin of Nichols' erroneous one-seventh figure.

  8. Electric-field-induced flow-aligning state in a nematic liquid crystal. (United States)

    Fatriansyah, Jaka Fajar; Orihara, Hiroshi


    The response of shear stress to a weak ac electric field as a probe is measured in a nematic liquid crystal under shear flow and dc electric fields. Two states with different responses are clearly observed when the dc electric field is changed at a constant shear rate: the flow aligning and non-flow aligning states. The director lies in the shear plane in the flow aligning state and out of the plane in the non-flow aligning state. Through application of dc electric field, the non-flow aligning state can be changed to the flow aligning state. In the transition from the flow aligning state to the non-flow aligning state, it is found that the response increases and the relaxation time becomes longer. Here, the experimental results in the flow aligning state are discussed on the basis of the Ericksen-Leslie theory.

  9. Power, politics and rehabilitation in sub-Saharan Africa: from the personal to the political. (United States)

    Campbell, Catherine


    This article discusses the complexities of facilitating community-based rehabilitation in resource-poor contexts in Sub-Saharan Africa. It does so through a reflection on the book Able-Bodied: Scenes from a Curious Life, written by Leslie Swartz, a South African expert on disability in the context of international development. Swartz uses his own personal experiences as son of a disabled father as a springboard for reflections on his long involvement in the often-fraught areas of disability research and activism. He pays particular attention to the way in which emotions shape the struggles around expertise and power that bedevil disability identity politics. In particular, his work highlights how the complex dynamics of race, class and disability undermine the effectiveness of the movement.

  10. Effect of surface tension on the dynamical behavior of bubble in rotating fluids under low gravity environment (United States)

    Hung, R. J.; Tsao, Y. D.; Leslie, Fred W.; Hong, B. B.


    Time dependent evolutions of the profile of free surface (bubble shapes) for a cylindrical container partially filled with a Newtonian fluid of constant density, rotating about its axis of symmetry, have been studied. Numerical computations of the dynamics of bubble shapes have been carried out with the following situations: (1) linear functions of spin-up and spin-down in low and microgravity environments, (2) linear functions of increasing and decreasing gravity enviroment in high and low rotating cylidner speeds, (3) step functions of spin-up and spin-down in a low gravity environment, and (4) sinusoidal function oscillation of gravity environment in high and low rotating cylinder speeds. The initial condition of bubble profiles was adopted from the steady-state formulations in which the computer algorithms have been developed by Hung and Leslie (1988), and Hung et al. (1988).

  11. Oppenheimer&Groves : The duality that led to Trinity /.

    Energy Technology Data Exchange (ETDEWEB)

    Connaughton, T. G. (Theresa G.); Smith, S. E. (Sharon E.)


    The alliance of J. Robert Oppenheimer, scientist, and Leslie R. Groves, military leader, is often interpreted as the classic example of the clash between the academic mind and the military style. Evidence suggests, instead, that it was a collaboration that led to the dawn of the nuclear age. Instead of a clash, it was collaboration and an implosion of the diverse talents needed for the success of this project. Discussion of these flawed and fascinating individuals still ignites controversy today. This presentation will explore the backgrounds and personalities of these two men and their work together to accomplish their mission. Was the aftermath inevitable, given a relationship based on respect, but perhaps not trust? The genesis of the modern military-industrial complex rested on the genius of these two men, though they personify two distinct American sub-cultures. What lessons can be drawn from their wartime and post-war relationship? What analogies can be drawn for current American values?

  12. Finite Time Blowup in a Realistic Food-Chain Model

    KAUST Repository

    Parshad, Rana


    We investigate a realistic three-species food-chain model, with generalist top predator. The model based on a modified version of the Leslie-Gower scheme incorporates mutual interference in all the three populations and generalizes several other known models in the ecological literature. We show that the model exhibits finite time blowup in certain parameter range and for large enough initial data. This result implies that finite time blowup is possible in a large class of such three-species food-chain models. We propose a modification to the model and prove that the modified model has globally existing classical solutions, as well as a global attractor. We reconstruct the attractor using nonlinear time series analysis and show that it pssesses rich dynamics, including chaos in certain parameter regime, whilst avoiding blowup in any parameter regime. We also provide estimates on its fractal dimension as well as provide numerical simulations to visualise the spatiotemporal chaos.

  13. Hydrodynamics of defects in the Abelian-Higgs model: An application to nematic liquid crystals

    International Nuclear Information System (INIS)

    Kurz, Guenter; Sarkar, Sarben


    The Abelian-Higgs model is the basis for a gauge covariant form of the distortion free energy for nematic liquid crystals. This is used to derive a new form of the Ericksen-Leslie equations incorporating the dynamics of disclinations in nematic films. The zero liquid flow case is treated in detail for simplicity. The equations are reduced to dynamic equations for disclination points in moduli space for a small deviation from the Bogomol'nyi limit. We are able to derive analytically the dynamics of disclinations with winding numbers of the same sign. A set of such disclinations close to one another, i.e., with overlapping cores, can result from the disintegration of a larger disclination, and they repel one another. For a pair of such dis- clinations far apart from one another we find that they move on a straight line where their separation increases logarithmically over time

  14. Were moas really hunted to extinction in less than 100 years?

    International Nuclear Information System (INIS)

    Wilkes, O.


    Three months ago New Zealand archaeologists were surprised to read in their daily newspapers that moas had been eaten to extinction by Maori moahunters in less than 100 years. The claim had been made in the US journal 'Science' by Richard Holdaway, formerly with Canterbury University, and Chris Jacomb of Canterbury Museum. It seems to me there are a number of weaknesses in the original paper, which should have been thrashed out locally before going for prestigious exposure overseas. The rapid extinction claim is based first of all on a 'Leslie matrix model' of moa population dynamics, and secondly on some recent carbon dates of a single archaeological site, Monck's Cave, near Christchurch. 21 refs

  15. Generalized nematohydrodynamic boundary conditions with application to bistable twisted nematic liquid-crystal displays

    KAUST Repository

    Fang, Angbo


    Parallel to the highly successful Ericksen-Leslie hydrodynamic theory for the bulk behavior of nematic liquid crystals (NLCs), we derive a set of coupled hydrodynamic boundary conditions to describe the NLC dynamics near NLC-solid interfaces. In our boundary conditions, translational flux (flow slippage) and rotational flux (surface director relaxation) are coupled according to the Onsager variational principle of least energy dissipation. The application of our boundary conditions to the truly bistable π -twist NLC cell reveals a complete picture of the dynamic switching processes. It is found that the thus far overlooked translation-rotation dissipative coupling at solid surfaces can accelerate surface director relaxation and enhance the flow rate. This can be utilized to improve the performance of electro-optical nematic devices by lowering the required switching voltages and reducing the switching times. © 2008 The American Physical Society.

  16. Some topics in continuum theory of liquid crystals

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Claire


    Since advancements by Ericksen and Leslie in the 1960's, interest in the continuum theory for liquid crystals has escalated. In this thesis, we present the well established continuum theory for nematics, and apply it to the simple Tsvetkov experiment. This analysis is further extended by studying a similar geometric setup which allows additional degrees of freedom. Steady state solutions are studied, and stable/unstable solutions discussed. The bulk of this thesis however, is concerned with the smectic continuum theory. The theory presented allows variable layer spacing, and hence goes beyond the scope of that proposed by Leslie, Stewart and Nakagawa in 1991. With this theory, we initially study a sample of SmA liquid crystal in the bookshelf geometry between two parallel plates, and subject to a strongly anchored pretilt at the boundaries. Weakly anchored solutions are also briefly discussed at the end of this chapter. This work is extended by considering the same problem with a SmC sample, and the distinct differences between the SmA and SmC solutions are highlighted. Symmetric chevron solutions of C1 and C2 type are discussed fully, and energy considerations are made to find the physically realistic configurations. Again, the last part of this chapter is dedicated to solutions subject to weak anchoring. Finally, we take a brief look at Freedericksz transitions when a magnetic field is applied across a cell containing a SmA sample in the bookshelf geometry. The Freedericksz thresholds for two possible deformations are obtained by linearising the appropriate equation, and solving the resulting eigenvalue problem. Numerical calculations finally show where the transitions occur, and confirm the accuracy of the threshold values obtained analytically. (author)

  17. Some topics in continuum theory of liquid crystals

    International Nuclear Information System (INIS)

    Anderson, Claire


    Since advancements by Ericksen and Leslie in the 1960's, interest in the continuum theory for liquid crystals has escalated. In this thesis, we present the well established continuum theory for nematics, and apply it to the simple Tsvetkov experiment. This analysis is further extended by studying a similar geometric setup which allows additional degrees of freedom. Steady state solutions are studied, and stable/unstable solutions discussed. The bulk of this thesis however, is concerned with the smectic continuum theory. The theory presented allows variable layer spacing, and hence goes beyond the scope of that proposed by Leslie, Stewart and Nakagawa in 1991. With this theory, we initially study a sample of SmA liquid crystal in the bookshelf geometry between two parallel plates, and subject to a strongly anchored pretilt at the boundaries. Weakly anchored solutions are also briefly discussed at the end of this chapter. This work is extended by considering the same problem with a SmC sample, and the distinct differences between the SmA and SmC solutions are highlighted. Symmetric chevron solutions of C1 and C2 type are discussed fully, and energy considerations are made to find the physically realistic configurations. Again, the last part of this chapter is dedicated to solutions subject to weak anchoring. Finally, we take a brief look at Freedericksz transitions when a magnetic field is applied across a cell containing a SmA sample in the bookshelf geometry. The Freedericksz thresholds for two possible deformations are obtained by linearising the appropriate equation, and solving the resulting eigenvalue problem. Numerical calculations finally show where the transitions occur, and confirm the accuracy of the threshold values obtained analytically. (author)

  18. Mutations in galactosemia

    Energy Technology Data Exchange (ETDEWEB)

    Reichardt, J.K.V. [Univ. of Southern California School of Medicine, Los Angeles, CA (United States)


    This Letter raises four issues concerning two papers on galactosemia published in the March 1995 of the Journal. First, table 2 in the paper by Elsas et al. incorrectly attributes seven galactose-l-phosphate uridyl transferase (GALT) mutations (S135L, L195P, K285N, N314D, R333W, R333G, and K334R). The table also fails to mention that others have reported the same two findings attributed to {open_quotes}Leslie et al.; Elsas et al. and in press{close_quotes} and {open_quotes}Leslie et al.; Elsas et al.{close_quotes} The first finding on the prevalence of the Q188R galactosemia mutation in the G/G Caucasian population has also been described by Ng et al., and the second finding on the correlation of the N314D GALT mutation with the Duarte variant was reported by Lin et al. Second, Elsas et al. suggest that the E203K and N314D mutations may {open_quotes}produce intra-allelic complementation when in cis{close_quotes}. This speculation is supported by the activity data of individual III-2 but is inconsistent with the activities of three other individuals I-1, II-1, and III-1 of the same pedigree. The GALT activity measured in these three individuals suggests a dominant negative effect of E203K in E203K-N314D chromosomes, since they all have less than normal activity. Thus, the preponderance of the data in this paper is at odds with the authors speculation. It is worth recalling that Lin et al. also identified four N314D GALT mutations on 95 galactosemic chromosomes examined. A similar situation also appears to be the case in proband III-1 (with genotype E203K-N314D/IVSC) in the Elsas et al. paper. 9 refs.

  19. Use of an interdisciplinary, participatory design approach to develop a usable patient self-assessment tool in atrial fibrillation

    Directory of Open Access Journals (Sweden)

    MacCallum L


    Full Text Available Lori MacCallum,1,2 Heather McGaw,1 Nazanin Meshkat,3 Alissia Valentinis,4 Leslie Beard Ashley,5 Rajan Sacha Bhatia,3,6,7 Kaye Benson,7 Noah Ivers,6,8 Kori Leblanc,2,7 Dante Morra3,5,7 1Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, 2Leslie Dan Faculty of Pharmacy, University of Toronto, 3Department of Medicine, University of Toronto, Toronto, 4Taddle Creek Family Health Team, Toronto, 5Trillium Health Partners, Mississauga, 6Women's College Hospital, Toronto, 7Centre for Innovation in Complex Care, University Health Network, Toronto, 8Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada Abstract: After identifying that significant care gaps exist within the management of atrial fibrillation (AF, a patient-focused tool was developed to help patients better assess and manage their AF. This tool aims to provide education and awareness regarding the management of symptoms and stroke risk associated with AF, while engaging patients to identify if their condition is optimally managed and to become involved in their own care. An interdisciplinary group of health care providers and designers worked together in a participatory design approach to develop the tool with input from patients. Usability testing was completed with 22 patients of varying demographics to represent the characteristics of the patient population. The findings from usability testing interviews were used to further improve and develop the tool to improve ease of use. A physician-facing tool was also developed to help to explain the tool and provide a brief summary of the 2012 Canadian Cardiovascular Society atrial fibrillation guidelines. By incorporating patient input and human-centered design with the knowledge, experience, and medical expertise of health care providers, we have used an approach in developing the tool that tries to more effectively meet patients' needs. Keywords: patient education, atrial fibrillation, care gaps

  20. Implicit assumptions underlying simple harvest models of marine bird populations can mislead environmental management decisions. (United States)

    O'Brien, Susan H; Cook, Aonghais S C P; Robinson, Robert A


    Assessing the potential impact of additional mortality from anthropogenic causes on animal populations requires detailed demographic information. However, these data are frequently lacking, making simple algorithms, which require little data, appealing. Because of their simplicity, these algorithms often rely on implicit assumptions, some of which may be quite restrictive. Potential Biological Removal (PBR) is a simple harvest model that estimates the number of additional mortalities that a population can theoretically sustain without causing population extinction. However, PBR relies on a number of implicit assumptions, particularly around density dependence and population trajectory that limit its applicability in many situations. Among several uses, it has been widely employed in Europe in Environmental Impact Assessments (EIA), to examine the acceptability of potential effects of offshore wind farms on marine bird populations. As a case study, we use PBR to estimate the number of additional mortalities that a population with characteristics typical of a seabird population can theoretically sustain. We incorporated this level of additional mortality within Leslie matrix models to test assumptions within the PBR algorithm about density dependence and current population trajectory. Our analyses suggest that the PBR algorithm identifies levels of mortality which cause population declines for most population trajectories and forms of population regulation. Consequently, we recommend that practitioners do not use PBR in an EIA context for offshore wind energy developments. Rather than using simple algorithms that rely on potentially invalid implicit assumptions, we recommend use of Leslie matrix models for assessing the impact of additional mortality on a population, enabling the user to explicitly define assumptions and test their importance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Modelling population-level consequences of chronic external gamma irradiation in aquatic invertebrates under laboratory conditions

    Energy Technology Data Exchange (ETDEWEB)

    Lance, Emilie [Laboratoire de modelisation pour l' expertise environnementale (LM2E) Institut de Radioprotection et de Surete Nucleaire (IRSN), PRP-ENV, SERIS, Cadarache (France); Alonzo, Frederic, E-mail: [Laboratoire d' ecotoxicologie des radionucleides (LECO) Institut de Radioprotection et de Surete Nucleaire (IRSN), PRP-ENV, SERIS, Cadarache (France); Garcia-Sanchez, Laurent [Laboratoire de biogeochimie, biodisponibilite et transferts des radionucleides (L2BT) Institut de Radioprotection et de Surete Nucleaire (IRSN), PRP-ENV, SERIS, Cadarache (France); Beaugelin-Seiller, Karine; Garnier-Laplace, Jacqueline [Laboratoire de modelisation pour l' expertise environnementale (LM2E) Institut de Radioprotection et de Surete Nucleaire (IRSN), PRP-ENV, SERIS, Cadarache (France)


    We modelled population-level consequences of chronic external gamma irradiation in aquatic invertebrates under laboratory conditions. We used Leslie matrices to combine life-history characteristics (duration of life stages, survival and fecundity rates) and dose rate-response curves for hatching, survival and reproduction fitted on effect data from the FREDERICA database. Changes in net reproductive rate R{sub 0} (offspring per individual) and asymptotic population growth rate {lambda} (dimensionless) were calculated over a range of dose rates in two marine polychaetes (Neanthes arenaceodentata and Ophryotrocha diadema) and a freshwater gastropod (Physa heterostropha). Sensitivities in R{sub 0} and {lambda} to changes in life-history traits were analysed in each species. Results showed that fecundity has the strongest influence on R{sub 0}. A delay in age at first reproduction is most critical for {lambda} independent of the species. Fast growing species were proportionally more sensitive to changes in individual endpoints than slow growing species. Reduction of 10% in population {lambda} were predicted at dose rates of 6918, 5012 and 74,131 {mu}Gy{center_dot}h{sup -1} in N. arenaceodentata, O. diadema and P. heterostropha respectively, resulting from a combination of strong effects on several individual endpoints in each species. These observations made 10%-reduction in {lambda} a poor criterion for population protection. The lowest significant changes in R{sub 0} and {lambda} were respectively predicted at a same dose rate of 1412 {mu}Gy h{sup -1} in N. arenaceodentata, at 760 and 716 {mu}Gy h{sup -1} in O. diadema and at 12,767 and 13,759 {mu}Gy h{sup -1} in P. heterostropha. These values resulted from a combination of slight but significant changes in several measured endpoints and were lower than effective dose rates calculated for the individual level in O. diadema and P. heterostropha. The relevance of the experimental dataset (external irradiation rather

  2. The Great Bravery of Croatian Soldier by Giuseppe Maria Mitelli

    Directory of Open Access Journals (Sweden)

    Daniel Premerl


    Full Text Available The article approaches the iconography of two etchings with Croatian subject matter made by the Bolognese etcher Giuseppe Maria Mitelli in 1684. In the focus is the etching Great Bravery of Croatian soldier (Gran prodezza di soldato croatto. The author concludes, interpreting the explanatory text below the etching, that it depicts an event of the so-called Great Turkish War (1683-1699. The depicted hero belonged to the Croatian Regiment commanded by general James Leslie, and the depicted heroic act occurred, in all probability, during the battle of Virovitica in 1684. Also, the author points out to a model for Mitelli's etching as well as to the literary image of the simultaneous decapitation of both a horseman and a horse in the Croatian literature. In the same year, Mitelli also made the portrait of the Zagreb bishop and the politician Martin Borković. The existence of both etchings is associated with the Illyrian-Hungarian College in Bologna, governed by the Zagreb cathedral Chapter. L'articolo indaga l'iconografia di due incisioni con soggetto croato realizzate dall'incisore bolognese Giuseppe Maria Mitelli nel 1684. Il focus del saggio è l'incisione Gran prodezza di soldato croatto. Interpretando il testo esplicativo sotto l'acquaforte, l'autore ritiene che essa raffiguri un evento della cosiddetta Grande Guerra Turca (1683-1699. L'eroe raffigurato apparteneva al reggimento croato comandato dal generale James Leslie e l'atto eroico raffigurato avvenne, con ogni probabilità, durante la battaglia di Virovitica nel 1684. L'autore individua inoltre un modello per l'incisione di Mitelli e un riferimento a una fonte nella letteratura croata ove compare la decapitazione simultanea di un cavaliere e di un cavallo. Nello stesso anno Mitelli fece anche il ritratto del vescovo di Zagabria e del politico Martin Borković. L'esistenza di entrambe le acqueforti è associata al Collegio illirico-ungarico di Bologna, governato dal Capitolo della

  3. Demography of a population collapse: the Northern Idaho ground squirrel (Spermophilus brunneus brunneus) (United States)

    Sherman, P.W.; Runge, M.C.


    We studied the demography of a population of Northern Idaho ground squirrels (Spermophilus brunneus brunneus) in Adams Co., Idaho. The population was completely censused yearly from 1987 to 1999, during which time it declined from 272 to 10 animals. The finite population growth rate, based on a Leslie matrix model of average life-history parameters, was only 0.72 (i.e., significantly conifers to encroach on inhabited meadows, shrinking them and closing dispersal routes. The proximate cause of the population's collapse was mortality of older breeding females, which reduced the mean age of breeders. Younger females had lower average pregnancy rates and litter sizes. To place our results in context we developed a new, general classification of anthropogenic population declines, based on whether they are caused by changes in the means of the life-history parameters (blatant disturbances), their variances (inappropriate variations), or the correlations among them (evolutionary traps). Many S. b. brunneus populations have disappeared in recent years, apparently due to blatant disturbances, especially loss of habitat and changes in food-plant composition, resulting in inadequate prehibernation nutrition and starvation overwinter. In addition, our study population may have been caught in an evolutionary trap, because the vegetational cues that could potentially enable the animals to adjust reproduction to the anticipated food supply no longer correlate with availability of fat-laden seeds.

  4. Precision platform for convex lens-induced confinement microscopy (United States)

    Berard, Daniel; McFaul, Christopher M. J.; Leith, Jason S.; Arsenault, Adriel K. J.; Michaud, François; Leslie, Sabrina R.


    We present the conception, fabrication, and demonstration of a versatile, computer-controlled microscopy device which transforms a standard inverted fluorescence microscope into a precision single-molecule imaging station. The device uses the principle of convex lens-induced confinement [S. R. Leslie, A. P. Fields, and A. E. Cohen, Anal. Chem. 82, 6224 (2010)], which employs a tunable imaging chamber to enhance background rejection and extend diffusion-limited observation periods. Using nanopositioning stages, this device achieves repeatable and dynamic control over the geometry of the sample chamber on scales as small as the size of individual molecules, enabling regulation of their configurations and dynamics. Using microfluidics, this device enables serial insertion as well as sample recovery, facilitating temporally controlled, high-throughput measurements of multiple reagents. We report on the simulation and experimental characterization of this tunable chamber geometry, and its influence upon the diffusion and conformations of DNA molecules over extended observation periods. This new microscopy platform has the potential to capture, probe, and influence the configurations of single molecules, with dramatically improved imaging conditions in comparison to existing technologies. These capabilities are of immediate interest to a wide range of research and industry sectors in biotechnology, biophysics, materials, and chemistry.

  5. Suppression of Transient Events by Levitation (STABLE): Results From the USML-2 Mission. Experiment 38 (United States)

    Nurre, Gerald S.; Edberg, Donald L.


    Microgravity science payloads can be extremely sensitive to vibrations from machinery, acoustics, ventilation, and crew activity. Suppression of Transient Acceleration by Levitation (STABLE) is an active vibration isolation system designed to protect payloads from these disturbances. This paper gives an account of results from the flight demonstration of the STABLE microgravity isolation system, which was developed and successfully flight tested in orbit during USML-2, with the participation of Astronaut Fred Leslie. Following a very brief description of the operational principles, the hardware and software design, and performance criteria, results of the analysis of measured flight data are presented to provide an evaluation of system performance parameters, including acceleration attenuation, assessment of sway space, system power consumption, and other factors critical to the performance of an isolation system. Lessons learned and potential design improvements and evolutions are discussed. Data reduction by Robert Boucher of McDonnell Douglas Aerospace (MDA) was substantially assisted by Kenneth Hrovat of Tal-Cut, Inc., under support from National Aeronautics and Space Administration/Lewis Research Center (LeRC), Cleveland, OH.

  6. Book review: A chorus of cranes: The cranes of North America and the world (United States)

    Pearse, Aaron T.


    Cranes (Gruidae) are widely distributed throughout the world, have lived on Earth for several million years, and currently reside on five continents. Archaeological evidence and historical references suggest that humans have interacted with and been captivated by cranes for many thousands of years (e.g., Leslie 1988, Muellner 1990). A glimpse of our reverence for these birds can be found in A Chorus of Cranes by Paul A. Johnsgard, with photographs by Thomas D. Mangelsen. Many species of cranes are currently identified as threatened or endangered, and their future will likely rest in the hands of humans; this book presents their plight and some of the measures that have been taken to conserve them. Dr. Johnsgard, an emeritus professor at the University of Nebraska-Lincoln, is a prolific writer, having written more than 60 books in ornithology and other topics. This book serves as the latest update of previous efforts concerning crane biology, conservation, and management. A review without making comparisons to his past works is difficult, yet this assessment will primarily focus on the content of the current book, with little reference to past endeavors.A Chorus of Cranes: The Cranes of North America and the World by Paul A. Johnsgard. 2015. University Press of Colorado, Boulder, CO, USA. x + 208 pp., 38 color photographs, 41 figures. ISBN 978-1-60732-436-2. $23.95 (Ebook). ISBN 978-1-60732-436-9.

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    W.F.L. Buschkens


    Full Text Available - Leslie H. Palmier, R. van Niel, The emergence of the modern Indonesian elite. The Hague and Bandung, W. van Hoeve Ltd., 1960. - A. Teeuw, Richard Winstedt, Kamus Bahasa Melayu. Marican & Sons, Singapore & Kuala Lumpur. 1960. 338 pp. - A. Teeuw, Richard Winstedt, An unabridged English-Malay Dictionary. Marican & Sons, Singapore. 398 pp. 2nd ed. with two appendices. id. 1960. 431 pp. - A. Teeuw, Richard Winstedt, An unabridged Malay-English dictionary. Kelly & Walsh Limited, Singapore. [+/- 1955]. 359 pp. 3rd ed. enlarged. Marican & Sons, Singapore & Kuala Lumpur. 1959. - A. Teeuw, John M. Echols, An Indonesian-English Dictionary. Cornell University Press, Ithaca, N.Y. 1961. XVI + 384 pp., Hassan Shadily (eds. - A. Teeuw, Chairil Anwar, Sharp Gravel, Indonesian Poems by Chairil Anwar. Translated by Donna M. Dickinson. [Reproduced and distributed by: Center for Southeast Asia Studies, University of California, Berkeley 4, California. 1960.] 91 pages. - A. Teeuw, H.B. Jassin, Chairil Anwar. Pelopor Angkatan 45. Satu pembitjaraan. Disertai kumpulan hasil-hasil tulisannja. Tjet. ke-2. Gunung Agung - Djakarta 1959. 161 pp. - W.F.L. Buschkens, William L. Thomas jr., Man, Time, and Space in Southern California. A Suplement “Annals of the Association of American Geographers”, Washington 6, D.C., Allen Press, Lawrence, Kansas; 120 blz.

  8. Etiology, diagnosis, and clinical management of vulvodynia

    Directory of Open Access Journals (Sweden)

    Sadownik LA


    Full Text Available Leslie A Sadownik University of British Columbia, Department of Obstetrics and Gynecology, Vancouver, BC, Canada Abstract: Chronic vulvar pain or discomfort for which no obvious etiology can be found, ie, vulvodynia, can affect up to 16% of women. It may affect girls and women across all age groups and ethnicities. Vulvodynia is a significant burden to society, the health care system, the affected woman, and her intimate partner. The etiology is multifactorial and may involve local injury or inflammation, and peripheral and or central sensitization of the nervous system. An approach to the diagnosis and management of a woman presenting with chronic vulvar pain should address the biological, psychological, and social/interpersonal factors that contribute to her illness. The gynecologist has a key role in excluding other causes for vulvar pain, screening for psychosexual and pelvic floor dysfunction, and collaborating with other health care providers to manage a woman's pain. An important component of treatment is patient education regarding the pathogenesis of the pain and the negative impact of experiencing pain on a woman's overall quality of life. An individualized, holistic, and often multidisciplinary approach is needed to effectively manage the woman's pain and pain-related distress. Keywords: vulvodynia, diagnosis, treatment, etiology, sexual pain disorder, dyspareunia, vestibulodynia, assessment, treatment, multidisciplinary

  9. Prevalence of osteoarthritis in individuals with COPD: a systematic review

    Directory of Open Access Journals (Sweden)

    Wshah A


    Full Text Available Adnan Wshah,1,2 Sara JT Guilcher,2,3 Roger Goldstein,1,2,4,5 Dina Brooks1,2,5 1Respiratory Medicine, West Park Healthcare Centre, Toronto, ON, Canada; 2Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, Canada; 3Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada; 4Department of Medicine, University of Toronto, Toronto, ON, Canada; 5Department of Physical Therapy, University of Toronto, Toronto, ON, Canada Abstract: The objective of this review was to examine the prevalence of osteoarthritis (OA in individuals with COPD. A computer-based literature search of CINAHL, Medline, PsycINFO and Embase databases was performed. Studies reporting the prevalence of OA among a cohort of individuals with COPD were included. The sample size varied across the studies from 27 to 52,643 with a total number of 101,399 individuals with COPD recruited from different countries. The mean age ranged from 59 to 76 years. The prevalence rates of OA among individuals with COPD were calculated as weighted means. A total of 14 studies met the inclusion criteria with a prevalence ranging from 12% to 74% and an overall weighted mean of 35.5%. Our findings suggest that the prevalence of OA is high among individuals with COPD and should be considered when developing and applying interventions in this population. Keywords: COPD, osteoarthritis, prevalence, comorbidities, pulmonary rehabilitation

  10. The case for policy-relevant conservation science. (United States)

    Rose, David C


    Drawing on the "evidence-based" (Sutherland et al. 2013) versus "evidence-informed" debate (Adams & Sandbrook 2013), which has become prominent in conservation science, I argue that science can be influential if it holds a dual reference (Lentsch & Weingart 2011) that contributes to the needs of policy makers whilst maintaining technical rigor. In line with such a strategy, conservation scientists are increasingly recognizing the usefulness of constructing narratives through which to enhance the influence of their evidence (Leslie et al. 2013; Lawton & Rudd 2014). Yet telling stories alone is rarely enough to influence policy; instead, these narratives must be policy relevant. To ensure that evidence is persuasive alongside other factors in a complex policy-making process, conservation scientists could follow 2 steps: reframe within salient political contexts and engage more productively in boundary work, which is defined as the ways in which scientists "construct, negotiate, and defend the boundary between science and policy" (Owens et al. 2006:640). These will both improve the chances of evidence-informed conservation policy. © 2015 The Authors. Conservation Biology published by Wiley Periodicals, Inc., on behalf of Society for Conservation Biology.

  11. Refining mortality estimates in shark demographic analyses: a Bayesian inverse matrix approach. (United States)

    Smart, Jonathan J; Punt, André E; White, William T; Simpfendorfer, Colin A


    Leslie matrix models are an important analysis tool in conservation biology that are applied to a diversity of taxa. The standard approach estimates the finite rate of population growth (λ) from a set of vital rates. In some instances, an estimate of λ is available, but the vital rates are poorly understood and can be solved for using an inverse matrix approach. However, these approaches are rarely attempted due to prerequisites of information on the structure of age or stage classes. This study addressed this issue by using a combination of Monte Carlo simulations and the sample-importance-resampling (SIR) algorithm to solve the inverse matrix problem without data on population structure. This approach was applied to the grey reef shark (Carcharhinus amblyrhynchos) from the Great Barrier Reef (GBR) in Australia to determine the demography of this population. Additionally, these outputs were applied to another heavily fished population from Papua New Guinea (PNG) that requires estimates of λ for fisheries management. The SIR analysis determined that natural mortality (M) and total mortality (Z) based on indirect methods have previously been overestimated for C. amblyrhynchos, leading to an underestimated λ. The updated Z distributions determined using SIR provided λ estimates that matched an empirical λ for the GBR population and corrected obvious error in the demographic parameters for the PNG population. This approach provides opportunity for the inverse matrix approach to be applied more broadly to situations where information on population structure is lacking. © 2018 by the Ecological Society of America.

  12. Investigación Crítica: Desafíos y Posibilidades

    Directory of Open Access Journals (Sweden)

    Fractalitats en Investigació Crítica (FIC


    Full Text Available La emergencia de las ciencias sociales está ligada a la constitución de una red de tecnologías, conocimientos, prácticas y discursos para regular y gobernar la sociedad; desarrollando formas de control en el que las ciencias sociales juegan un papel central. La actual sociedad del conocimiento gestiona la producción de conocimiento científico que maximiza las aportaciones coherentes con el pensamiento hegemónico y dificulta el desarrollo de perspectivas críticas (Slaughter y Leslie, 1997, 2001. Las ciencias sociales se encuentran en la paradoja de cuestionar los fundamentos de aquello en que, de un modo u otro, participan constitutivamente. El desarrollo de la sociedad post-fordista y nuestra localización en la barriga del monstruo (Haraway, 1991 plantea la necesidad de una reflexión sobre el contexto, las posibilidades y las formas de un trabajo crítico en el presente marco institucional. Exploramos principios metodológicos y formas de investigación a considerar en el planteamiento de una ?investigación crítica?, a la vez que nos preguntamos por las posibilidades mismas del trabajo académico de carácter crítico.

  13. Immunogenetic Management Software: a new tool for visualization and analysis of complex immunogenetic datasets. (United States)

    Johnson, Z P; Eady, R D; Ahmad, S F; Agravat, S; Morris, T; Else, J; Lank, S M; Wiseman, R W; O'Connor, D H; Penedo, M C T; Larsen, C P; Kean, L S


    Here we describe the Immunogenetic Management Software (IMS) system, a novel web-based application that permits multiplexed analysis of complex immunogenetic traits that are necessary for the accurate planning and execution of experiments involving large animal models, including nonhuman primates. IMS is capable of housing complex pedigree relationships, microsatellite-based MHC typing data, as well as MHC pyrosequencing expression analysis of class I alleles. It includes a novel, automated MHC haplotype naming algorithm and has accomplished an innovative visualization protocol that allows users to view multiple familial and MHC haplotype relationships through a single, interactive graphical interface. Detailed DNA and RNA-based data can also be queried and analyzed in a highly accessible fashion, and flexible search capabilities allow experimental choices to be made based on multiple, individualized and expandable immunogenetic factors. This web application is implemented in Java, MySQL, Tomcat, and Apache, with supported browsers including Internet Explorer and Firefox on Windows and Safari on Mac OS. The software is freely available for distribution to noncommercial users by contacting A demonstration site for the software is available at , user name: and password: imsdemo.

  14. Demografía poblacional de Rhinella arenarum (Anura: Bufonidae y Physalaemus biligonigerus (Anura: Leiuperidae en agroecosistemas de la provincia de Córdoba, Argentina

    Directory of Open Access Journals (Sweden)

    Clarisa Bionda


    Full Text Available El crecimiento de la agricultura produce pérdida del hábitat natural, con consecuencias para la biodiversidad de los anfibios. Se analizó la demografía poblacional de dos especies de anfibios en agroecosistemas de la provincia de Córdoba, Rhinella arenarum y Physalaemus biligonigerus. Los muestreos se realizaron en tres agroecosistemas y en un cuarto sitio, no afectado por cultivos. Los individuos se capturaron utilizando trampas de caída viva y relevamientos visuales. Con los datos de abundancia se estimó la supervivencia para cada clase de edad y con las tasas de supervivencia y fertilidad poblacional, se construyeron matrices de Leslie para obtener una proyección cuantitativa del tamaño poblacional. Las proyecciones poblacionales fueron favorables para el sitio SM2 y desfavorables para los sitios cultivados. Los agroecosistemas son ambientes posiblemente inhóspitos para la reproducción y supervivencia de las especies estudiadas. Particularmente se ven afectados aquellos estadios acuáticos del ciclo de vida de estas especies, debido al deterioro de los cuerpos de agua en estas áreas. Se reconocieron efectos especie-específicos de los ecosistemas agrícolas, ya que P. biligonigerus resultó la especie más afectada. Se sugiere un deterioro ambiental producido por cultivos extensivos de soja, lo que impactaría la demografía de las poblaciones de anuros.

  15. University Research in Support of TREAT Modeling and Simulation, FY 2016

    Energy Technology Data Exchange (ETDEWEB)

    DeHart, Mark David [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    Idaho National Laboratory is currently evolving the modeling and simulation (M&S) capability that will enable improved core operation as well as design and analysis of TREAT experiments. This M&S capability primarily uses MAMMOTH, a reactor physics application being developed under the Multi-physics Object Oriented Simulation Environment (MOOSE) framework. MAMMOTH allows the coupling of a number of other MOOSE-based applications. In support of this research, INL is working with four universities to explore advanced solution methods that will complement or augment capabilities in MAMMOTH. This report consists of a collection of year end summaries of research from the universities performed in support of TREAT modeling and simulation. This research was led by Prof. Sedat Goluoglu at the University of Florida, Profs. Jim Morel and Jean Ragusa at Texas A&M University, Profs. Benoit Forget and Kord Smith at Massachusetts Institute of Technology, Prof. Leslie Kerby of Idaho State University and Prof. Barry Ganapol of University of Arizona. A significant number of students were supported at various levels though the projects and, for some, also as interns at INL.

  16. Highlights: Spring Council Meeting (United States)

    Council members present at the May 24, 1981, meeting were Keiiti Aki, Steven Burges (for Jim Wallis), Peter S. Eagleson, E. R. Engdahl, Charles E. Helsley, James R. Heirtzler, Carl Kisslinger, Leslie H. Meredith, Chris N. K. Mooers, Norman F. Ness, Marcia M. Neugebauer, James J. O'Brien, Richard Rapp, Carl Sagan, James C. Savage, Joseph V. Smith, Fred Spilhaus, Donald L. Turcotte, James A. Van Allen, J. Tuzo Wilson, and Jay Winston (for Elmar R. Reiter until his arrival at 6:50 P.M.). David Strangway, representing the Canadian Geophysical Union, and Peter Steinhauser, representing the European Geophysical Society, were special observers at the meeting. Council meetings are open, and a number of section secretaries, committee chairmen, journal editors, and other members attended. The following major actions were adopted by the Council:The experiment of publishing oceanography and lower-atmosphere papers in JGR Green issues alternate to those containing upper-atmosphere papers will be continued through 1982. From preliminary indications the experiment seems to be working, but a full year of data, including a renewal cycle, is needed to assess the success of the experiment. Final decision will be made prior to the 1983 dues notices.

  17. [Specificity hypothesis of a theory of mind deficit in early childhood autism]. (United States)

    Kissgen, R; Schleiffer, R


    In order to test the hypothesis that a theory of mind deficit is specific for autism, the present study presents the first replication of the Sally-Anne test (Baron-Cohen, Leslie & Frith, 1985) in the German-speaking countries. The Sally-Anne test was administered to 16 autistic, 24 probands with Down's syndrome and 20 normal preschool prosands. The intelligence of the autistic group and that with Down's syndrome was measured by the CPM/SPM. In addition, the ADI-R was used with the principal caregivers of the autistic and Down's syndrome subjects. With regard to the clinical diagnosis, theory of mind deficit turned out to be not specific for autism. Six of 16 (37.5%) autistic subjects passed the theory of mind tasks. Thus performance in the autistic group surpassed that of both control groups. Out of 16 autistic subjects, autism could be confirmed in only 8 on the basis of the ADI-R diagnostic criteria, only one of whom showed a theory of mind. The autistic individuals with a theory of mind differed significantly in their mean IQ from those without this ability. Spectrum and specificity of a theory of mind deficit in autism remain controversial. For further research it seems important to administer the ADI-R during the diagnostic process. The findings suggest that the clinical diagnosis of autism is not precise enough to distinguish between autism and nonautistic mental handicap.

  18. Spitzer - Hot & Colorful Student Activities (United States)

    McDonald, D.; Rebull, L. M.; DeWolf, C.; Guastella, P.; Johnson, C. H.; Schaefers, J.; Spuck, T.; McDonald, J. G., III; DeWolf, T.; Brock, S.; Boerma, J.; Bemis, G.; Paulsen, K.; Yueh, N.; Peter, A.; Wassmer, W.; Haber, R.; Scaramucci, A.; Butchart, J.; Holcomb, A.; Karns, B.; Kennedy, S.; Siegel, R.; Weiser, S.


    In this poster, we present the results of several activities developed for the general science student to explore infrared light. The first activity involved measuring infrared radiation using an updated version of Newton's experiment of splitting white light and finding IR radiation. The second used Leslie's cube to allow students to observe different radiators, while the third used a modern infrared thermometer to measure and identify IR sources in an enclosed box. The last activity involved students making false-color images from narrow-band filter images from data sets from Spitzer Space Telescope, STScI Digitized Sky Survey and other sources. Using computer programs like Adobe Photoshop and free software such as ds9, Spot and Leopard, poster-like images were created by the students. This research is funded by the Spitzer Science Center (SSC) and the National Optical Astronomy Observatory (NOAO). Please see our companion poster, Johnson et al., on the science aspect of this program, and another poster on the educational aspects, Guastella et al.


    CERN Multimedia



    Thursday 11 November 2010 at 20:30 / Jeudi 11 Novembre 2010 à 20:30 CERN Main Auditorium / Amphithéâtre Principal LE CHOCOLAT By/de : Lasse Hallström (UK/USA, 2000) 121 min With/avec: Lena Olin, Juliette Binoche, Johny Depp, Judi Dench, Alfred Molina, Peter Stormare, Leslie Caron, Carrie-Anne Moss   Vianne Rocher and her young daughter are drifters who are met with skepticism and resistance when they move to a conservative town in rural France and open a chocolate shop during Lent. As Vianne begins to work her magic and help those around her, the townspeople are soon won over by her exuberance and her delicious chocolates - except for the mayor, who is determined to shut her down. When a group of river drifters visit the town, Vianne teaches the townspeople something about acceptance, and finds love for herself along the way. Original version english / french with german subtitles Version originale anglaise / française soutitr&...

  20. Two days of films

    CERN Document Server


    The Chinese community at CERN and the CERN CineClub, on the occasion of the Chinese New Year, invite everyone to two days of films Thursday 3 February 2011 at 20:30 - CERN Council Chamber Eat drink man woman Directed by Ang LEE (Taiwan, 1994) 122 min. With Sihung Lung, Yu-Wen Wang, Chien-Lien Wu, Kuei-Mei Yang Senior Master Chef Chu lives in a large house in Taipei with his three unmarried daughters, Jia-Jen, a chemistry teacher converted to Christianity, Jia-Chien, an airline executive, and Jia-Ning, a student who also works in a fast food restaurant. Life in the house revolves around the ritual of an elaborate dinner each Sunday, and the love lives of all the family members. Original version Mandarin with English subtitles Friday 4 February 2011 at 19:30 - CERN Council Chamber Adieu, ma concubine Directed by Chen KAIGE (China / Hong Kong, 1993) 171 min. With Leslie Cheung, Fengyi Zhang, Li Gong "Farewell, My Concubine" is a movie with two parallel, intertwined stories. It is the story of two performers in t...

  1. Health seeking behaviour and challenges in utilising health facilities in Wakiso district, Uganda. (United States)

    Musoke, David; Boynton, Petra; Butler, Ceri; Musoke, Miph Boses


    The health seeking behaviour of a community determines how they use health services. Utilisation of health facilities can be influenced by the cost of services, distance to health facilities, cultural beliefs, level of education and health facility inadequacies such as stock-out of drugs. To assess the health seeking practices and challenges in utilising health facilities in a rural community in Wakiso district, Uganda. The study was a cross sectional survey that used a structured questionnaire to collect quantitative data among 234 participants. The sample size was obtained using the formula by Leslie Kish. While 89% of the participants were aware that mobile clinics existed in their community, only 28% had received such services in the past month. The majority of participants (84%) did not know whether community health workers existed in their community. The participants' health seeking behaviour the last time they were sick was associated with age (p = 0.028) and occupation (p = 0.009). The most significant challenges in utilising health services were regular stock-out of drugs, high cost of services and long distance to health facilities. There is potential to increase access to health care in rural areas by increasing the frequency of mobile clinic services and strengthening the community health worker strategy.

  2. Portland Energy Centre: Securing supply and clearing the air

    International Nuclear Information System (INIS)


    The rationale for, and benefits derivable from the proposed Portland natural gas-fired cogeneration plant, to be located beside the former Hearn power station near the Leslie Street Spit in Toronto, are discussed. The justification for and the single most important benefit promised by the proposed plant is that it could help Ontario achieve its coal phase-out target by displacing 100 per cent of the annual output of the Lakeview coal--fired power plant in Mississauga, as well as six per cent of the annual output of the Nanticoke coal-fired power plant, in total supplying about 10 per cent of Toronto's electricity needs and providing steam to heat several office towers in downtown Toronto. Other benefits discussed include substantially improved air quality, reduced incidence of asthma and heart attacks, a more reliable power supply for Toronto, some 500 new jobs during construction, and 25 to 35 permanent jobs to operate the plant. The Fact Sheet also offers suggestions on how to generate political support for this project in particular and for renewable power sources in general

  3. Referential communication abilities and Theory of Mind development in preschool children. (United States)

    Resches, Mariela; Pérez Pereira, Miguel


    This work aims to analyse the specific contribution of social abilities (here considered as the capacity for attributing knowledge to others) in a particular communicative context. 74 normally developing children (aged 3;4 to 5;9, M = 4.6) were given two Theory of Mind (ToM) tasks, which are considered to assess increasing complexity levels of epistemic state attribution: Attribution of knowledge-ignorance (Pillow, 1989; adapted by Welch-Ross, 1997) and Understanding of False-belief (Baron Cohen, Leslie & Frith, 1985). Subjects were paired according to their age and level of performance in ToM tasks. These dyads participated in a referential communication task specially designed for this research. The resulting communicative interchanges were analysed using a three-level category system (pragmatic functions, descriptive accuracy, and ambiguity of messages). The results showed significant differences among subjects with different levels of social comprehension regarding the type of communicative resources used by them in every category level. In particular, understanding of false belief seems to be the most powerful predictor of changes in the children's development of communicative competence.

  4. Frontier nurse-midwives and antepartum emergencies, 1925 to 1939. (United States)

    Schminkey, Donna L; Keeling, Arlene W


    This article examines how the Frontier Nursing Service (FNS) utilized nurse-midwives to respond to antepartum emergencies such as preterm birth, eclampsia, malpresentation, and hemorrhage in the women of Appalachia in the years 1925 to 1939. Particular attention is given to the preparation that nurse-midwives received during their midwifery education to prevent and respond to emergencies. Using traditional historical research methods and primary source material from the FNS papers in the Special Collections, University of Kentucky Libraries, Lexington, Kentucky, this article describes the nurse-midwives' experiences and how they implemented skills they had learned during their training in Great Britain. Working in the isolated mountainous area of Leslie County, Kentucky-for the most part without direct assistance from physicians-FNS nurse-midwives decreased maternal and neonatal mortality rates. During their first 2000 births, they had only 2 maternal deaths, whereas the national average maternal mortality rate was approximately 7 deaths per 1000 births. The nurse-midwives performed external cephalic versions on a routine basis. For pregnancy and birth emergencies, they administered sedation, gave general anesthesia, and performed invasive lifesaving techniques in order to protect the lives of the women in their care. During these 14 years, their cross-cultural engagement, assessment skills, clinical judgment, and timely interventions improved maternal and child health throughout the region. © 2015 by the American College of Nurse-Midwives.

  5. Who should be performing routine abdominal ultrasound? A prospective double-blind study comparing the accuracy of radiologist and radiographer

    International Nuclear Information System (INIS)

    Leslie, A.; Lockyer, H.; Virjee, J.P.


    AIM: To compare the accuracy of radiographers and radiologists in routine abdominal ultrasound. MATERIALS AND METHODS: One hundred consecutive patients attending for routine abdominal ultrasound were included. Each patient was examined by both a radiographer and radiologist. Both operators noted their findings and wrote a concluding report without conferring. Reports were compared. Where there was disagreement the patient was either re-examined by another radiologist or had further investigation. RESULTS: Of 100 patients, 52 were men and 48 were women. The age range was 19-88 years (median 52 years). Thirty-seven patients had renal tract ultrasound, one had an aortic ultrasound and 62 had general upper abdominal ultrasound. In 44 cases both operators reported the examination as normal. In 49 cases both operators reported the examinations as abnormal and there was complete agreement between the operators. In seven cases there was not complete agreement between operators. Three of these disagreements were considered minor and four major. In three of the seven cases the radiographer was correct, and in four the radiologist was correct. CONCLUSION: Experienced radiographers and radiologists are highly accurate in performing and interpreting routine abdominal sonography. Both operators missed a small minority of abnormalities. There was no statistically significant difference in the accuracy of radiographers and radiologist. Leslie, A. (2000)

  6. Bourdieu, Department Chairs and the Reform of Science Education (United States)

    Melville, Wayne; Hardy, Ian; Bartley, Anthony


    Using the insights of the French sociologist, Pierre Bourdieu, this article considers the role of the science department chair in the reform of school science education. Using Bourdieu's 'thinking tools' of 'field', 'habitus' and 'capital', we case study the work of two teachers who both actively pursue the teaching and learning of science as inquiry. One teacher, Dan, has been a department chair since 2000, and has actively encouraged his department to embrace science as inquiry. The other teacher, Leslie, worked for one year in Dan's department before being transferred to another school where science teaching continues to be more traditional. Our work suggests that there are three crucial considerations for chairs seeking to lead the reform of science teaching within their department. The first of these is the development of a reform-minded habitus, as this appears to be foundational to the capital that can be expended in the leadership of reform. The second is an understanding of how to wield power and position in the promotion of reform. The third is the capacity to operate simultaneously and strategically within, and across, two fields; the departmental field and the larger science education field. This involves downplaying administrative logics, and foregrounding more inquiry-focused logics as a vehicle to challenge traditional science-teaching dispositions-the latter being typically dominated by concerns about curriculum 'coverage'.

  7. Population dynamics in variable environments

    CERN Document Server

    Tuljapurkar, Shripad


    Demography relates observable facts about individuals to the dynamics of populations. If the dynamics are linear and do not change over time, the classical theory of Lotka (1907) and Leslie (1945) is the central tool of demography. This book addresses the situation when the assumption of constancy is dropped. In many practical situations, a population will display unpredictable variation over time in its vital rates, which must then be described in statistical terms. Most of this book is concerned with the theory of populations which are subject to random temporal changes in their vital rates, although other kinds of variation (e. g. , cyclical) are also dealt with. The central questions are: how does temporal variation work its way into a population's future, and how does it affect our interpretation of a population's past. The results here are directed at demographers of humans and at popula­ tion biologists. The uneven mathematical level is dictated by the material, but the book should be accessible to re...

  8. Population characteristics and the suppression of nonnative Burbot (United States)

    Klein, Zachary B.; Quist, Michael C.; Rhea, Darren T.; Senecal, Anna C.


    Burbot Lota lota were illegally introduced into the Green River, Wyoming, drainage and have since proliferated throughout the system. Burbot in the Green River pose a threat to native species and to socially, economically, and ecologically important recreational fisheries. Therefore, managers of the Green River are interested in implementing a suppression program for Burbot. We collected demographic data on Burbot in the Green River (summer and autumn 2013) and used the information to construct an age-based population model (female-based Leslie matrix) to simulate the population-level response of Burbot to the selective removal of different age-classes. Burbot in the Green River grew faster, matured at relatively young ages, and were highly fecund compared with other Burbot populations within the species’ native distribution. The age-structured population model, in conjunction with demographic information, indicated that the Burbot population in the Green River could be expected to increase under current conditions. The model also indicated that the Burbot population in the Green River would decline once total annual mortality reached 58%. The population growth of Burbot in the Green River was most sensitive to age-0 and age-1 mortality. The age-structured population model indicated that an increase in mortality, particularly for younger age-classes, would result in the effective suppression of the Burbot population in the Green River.

  9. Terrestrial population models for ecological risk assessment: A state-of-the-art review (United States)

    Emlen, J.M.


    Few attempts have been made to formulate models for predicting impacts of xenobiotic chemicals on wildlife populations. However, considerable effort has been invested in wildlife optimal exploitation models. Because death from intoxication has a similar effect on population dynamics as death by harvesting, these management models are applicable to ecological risk assessment. An underlying Leslie-matrix bookkeeping formulation is widely applicable to vertebrate wildlife populations. Unfortunately, however, the various submodels that track birth, death, and dispersal rates as functions of the physical, chemical, and biotic environment are by their nature almost inevitably highly species- and locale-specific. Short-term prediction of one-time chemical applications requires only information on mortality before and after contamination. In such cases a simple matrix formulation may be adequate for risk assessment. But generally, risk must be projected over periods of a generation or more. This precludes generic protocols for risk assessment and also the ready and inexpensive predictions of a chemical's influence on a given population. When designing and applying models for ecological risk assessment at the population level, the endpoints (output) of concern must be carefully and rigorously defined. The most easily accessible and appropriate endpoints are (1) pseudoextinction (the frequency or probability of a population falling below a prespecified density), and (2) temporal mean population density. Spatial and temporal extent of predicted changes must be clearly specified a priori to avoid apparent contradictions and confusion.

  10. The behavior of surface tension on steady-state rotating fluids in the low gravity environments (United States)

    Hung, R. J.; Leslie, Fred W.


    The effect of surface tension on steady-state rotating fluids in a low gravity environment is studied. All the values of the physical parameters used in these calculations, except in the low gravity environments, are based on the measurements carried out by Leslie (1985) in the low gravity environment of a free-falling aircraft. The profile of the interface of two fluids is derived from Laplace's equation relating the pressure drop across an interface to the radii of curvature which has been applied to a low gravity rotating bubble that contacts the container boundary. The interface shape depends on the ratio of gravity to surface tension forces, the ratio of centrifugal to surface tension forces, the contact radius of the interface to the boundary, and the contact angle. The shape of the bubble is symmetric about its equator in a zero-gravity environment. This symmetry disappears and gradually shifts to parabolic profiles as the gravity environment becomes non-zero. The location of the maximum radius of the bubble moves upward from the center of the depth toward the top boundary of the cylinder as gravity increases. The contact radius of interface to the boundary r0 at the top side of cylinder increases and r0 at the bottom side of the cylinder decreases as the gravity environment increases from zero to 1 g.

  11. Reaching the next generation of nuclear engineers

    International Nuclear Information System (INIS)

    Djokic, Denia; Fratoni, Massimiliano


    The University of California, Berkeley (UCB) American Nuclear Society (ANS) Student Section hosted two outreach events for young students between the ages of seven and twelve. The students were part of a private after-school club called Adventures Through Open Minds Science TM club for kids (A.T.O.M.S. club for kids) heated by Leslie Buchalter. Buchalter is an expert in early education and teaches children fundamental scientific concepts by using 'kid language' and associating usually difficult ideas with something even the very young children can understand. The greatest challenge for us UCB student organizers was to follow this manner of teaching and to construct activities that would always keep the attention of the children. We put together an array of fundamental concept demonstrations based on this philosophy. For example, the concept of half-life was taught by repeatedly tossing M and M's onto a surface and removing the upside down M and M's, and the concept of a nuclear chain reaction was introduced using a mousetrap-and-ping-pong-ball contraption. The main lessons learned were that the children most successfully absorbed ideas by engaging the students activity in the concept demonstrations, by using concepts and vocabulary already familiar to them which encouraged them to answer questions about familiar topics, and by creating a playful game out of every learning opportunity. (author)

  12. The increasing globalization of health librarianship: a brief survey of international trends and activities. (United States)

    Madge, Bruce; Plutchak, T Scott


    Throughout his career, Leslie Morton was interested in international developments in health librarianship. In memory of the work he did in this field, the authors examine current developments in international health librarianship and describe some current themes. The authors draw from their combined experience in international activities and the published information available from selected library associations and related organizations. Although many of the major health library associations around the world are tackling agendas specific to their own country, issues of international concern are emerging in common. These are grouped around globalization, partnerships and co-operation, electronic access, especially open access, and working with the developing world in a number of different ways. Of course, the basis of all of these initiatives is to improve the health of the population by providing the best possible access to materials. Professional associations can provide a useful institutional infrastructure for addressing issues of international interest. Librarians should encourage their associations to develop these international initiatives and to seek out new and innovative ways to work together across international boundaries.

  13. A Mixed-Methods Study on the Impact of Socratic Seminars on Eighth Grade Students' Comprehension of Science Texts (United States)

    Roncke, Nancy

    This formative, convergent-mixed methods research study investigated the impact of Socratic Seminars on eighth grade science students' independent comprehension of science texts. The study also highlighted how eighth grade students of varying reading abilities interacted with and comprehended science texts differently during and after the use of Socratic Seminars. In order to document any changes in the students' overall comprehension of science texts, this study compared the experimental and control groups' pre- and post-test performances on the Content Area Reading Assessment (Leslie & Caldwell, 2014) and self-perception surveys on students' scientific reading engagement. Student think-alouds and interviews also captured the students' evolving understandings of the science texts. At the conclusion of this sixteen-week study, the achievement gap between the experimental and control group was closed in five of the seven categories on the Content Area Reading Assessment, including supporting an inference with textual evidence, determining central ideas, explaining why or how, determining word meaning, and summarizing a science text. Students' self-perception surveys were more positive regarding reading science texts after the Socratic Seminars. Finally, the student think-alouds revealed that some students moved from a literal interpretation of the science texts to inquiries that questioned the text and world events.

  14. Motor and verbal perspective taking in children with Autism Spectrum Disorder: Changes in social interaction with people and tools. (United States)

    Studenka, Breanna E; Gillam, Sandra L; Hartzheim, Daphne; Gillam, Ronald B


    Children with Autism Spectrum Disorder (ASD) have difficulty communicating with others nonverbally, via mechanisms such as hand gestures, eye contact and facial expression. Individuals with ASD also have marked deficits in planning future actions (Hughes, 1996), which might contribute to impairments in non-verbal communication. Perspective taking is typically assessed using verbal scenarios whereby the participant imagines how an actor would interact in a social situation (e.g., Sally Anne task; Baron-Cohen, Leslie, & Frith, 1985). The current project evaluated motor perspective taking in five children with ASD (8-11 years old) as they participated in a narrative intervention program over the course of about 16 weeks. The goal of the motor perspective-taking task was to facilitate the action of an experimenter either hammering with a tool or putting it away. Initially, children with ASD facilitated the experimenter's action less than neurotypical control children. As the narrative intervention progressed, children with ASD exhibited increased motor facilitation that paralleled their increased use of mental state and causal language, indicating a link between verbal and motor perspective taking. Motoric perspective taking provides an additional way to assess understanding and communication in children with ASD and may be a valuable tool for both early assessment and diagnosis of children with ASD. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Topological transitions in unidirectional flow of nematic liquid crystal (United States)

    Cummings, Linda; Anderson, Thomas; Mema, Ensela; Kondic, Lou


    Recent experiments by Sengupta et al. (Phys. Rev. Lett. 2013) revealed interesting transitions that can occur in flow of nematic liquid crystal under carefully controlled conditions within a long microfluidic channel of rectangular cross-section, with homeotropic anchoring at the walls. At low flow rates the director field of the nematic adopts a configuration that is dominated by the surface anchoring, being nearly parallel to the channel height direction over most of the cross-section; but at high flow rates there is a transition to a flow-dominated state, where the director configuration at the channel centerline is aligned with the flow (perpendicular to the channel height direction). We analyze simple channel-flow solutions to the Leslie-Ericksen model for nematics. We demonstrate that two solutions exist, at all flow rates, but that there is a transition between the elastic free energies of these solutions: the anchoring-dominated solution has the lowest energy at low flow rates, and the flow-dominated solution has lowest energy at high flow rates. NSF DMS 1211713.

  16. Bookreviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV


    Full Text Available Afro-Atlantic Dialogues: Anthropology in the Diaspora, edited by Kevin A. Yelvington (reviewed by Aisha Khan Central Africans, Atlantic Creoles, and the Foundation of the Americas, 1585-1660, by Linda M. Heywood & John K. Thornton (reviewed by James H. Sweet An Eye for the Tropics: Tourism, Photography, and Framing the Caribbean Picturesque, by Krista A. Thompson (reviewed by Carl Thompson Taíno Indian Myth and Practice: The Arrival of the Stranger King, by William F. Keegan (reviewed by Frederick H. Smith Historic Cities of the Americas: An Illustrated Encyclopedia, by David F. Marley (reviewed by Richard L. Kagan Arming Slaves: From Classical Times to the Modern Age, edited by Christopher Leslie Brown & Philip D. Morgan (reviewed by James Sidbury Sweet Negotiations: Sugar, Slavery, and Plantation Agriculture in Early Barbados, by Russell R. Menard (reviewed by Kenneth Morgan Jamaica in 1850 or, The Effects of Sixteen Years of Freedom on a Slave Colony, by John Bigelow (reviewed by Jean Besson Moral Capital: Foundations of British Abolitionism, by Christopher Leslie Brown (reviewed by Cassandra Pybus Caribbean Journeys: An Ethnography of Migration and Home in Three Family Networks, by Karen Fog Olwig (reviewed by George Gmelch Afro-Caribbean Immigrants and the Politics of Incorporation: Ethnicity, Exception, or Exit, by Reuel R. Rogers (reviewed by Kevin Birth Puerto Rican Arrival in New York: Narratives of the Migration, 1920-1950, edited by Juan Flores (reviewed by Wilson A. Valentín-Escobar The Conquest of History: Spanish Colonialism and National Histories in the Nineteenth Century, by Christopher Schmidt-Nowara (reviewed by Aline Helg Gender and Slave Emancipation in the Atlantic World, edited by Pamela Scully & Diana Paton (reviewed by Bernard Moitt Gender and Democracy in Cuba, by Ilja A. Luciak (reviewed by Florence E. Babb The “New Man” in Cuba: Culture and Identity in the

  17. A One Health overview, facilitating advances in comparative medicine and translational research. (United States)

    Stroud, Cheryl; Dmitriev, Igor; Kashentseva, Elena; Bryan, Jeffrey N; Curiel, David T; Rindt, Hans; Reinero, Carol; Henry, Carolyn J; Bergman, Philip J; Mason, Nicola J; Gnanandarajah, Josephine S; Engiles, Julie B; Gray, Falon; Laughlin, Danielle; Gaurnier-Hausser, Anita; Wallecha, Anu; Huebner, Margie; Paterson, Yvonne; O'Connor, Daniel; Treml, Laura S; Stannard, James P; Cook, James L; Jacobs, Marc; Wyckoff, Gerald J; Likins, Lee; Sabbagh, Ubadah; Skaff, Andrew; Guloy, Amado S; Hays, Harlen D; LeBlanc, Amy K; Coates, Joan R; Katz, Martin L; Lyons, Leslie A; Johnson, Gayle C; Johnson, Gary S; O'Brien, Dennis P; Duan, Dongsheng; Calvet, James P; Gandolfi, Barbara; Baron, David A; Weiss, Mark L; Webster, Debra A; Karanu, Francis N; Robb, Edward J; Harman, Robert J


    A1 One health advances and successes in comparative medicine and translational researchCheryl StroudA2 Dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanomaIgor Dmitriev, Elena Kashentseva, Jeffrey N. Bryan, David T. CurielA3 Viroimmunotherapy for malignant melanoma in the companion dog modelJeffrey N. Bryan, David Curiel, Igor Dmitriev, Elena Kashentseva, Hans Rindt, Carol Reinero, Carolyn J. HenryA4 Of mice and men (and dogs!): development of a commercially licensed xenogeneic DNA vaccine for companion animals with malignant melanomaPhilip J. BergmanA5 Successful immunotherapy with a recombinant HER2-expressing Listeria monocytogenes in dogs with spontaneous osteosarcoma paves the way for advances in pediatric osteosarcomaNicola J. Mason, Josephine S. Gnanandarajah, Julie B. Engiles, Falon Gray, Danielle Laughlin, Anita Gaurnier-Hausser, Anu Wallecha, Margie Huebner, Yvonne PatersonA6 Human clinical development of ADXS-HER2Daniel O'ConnorA7 Leveraging use of data for both human and veterinary benefitLaura S. TremlA8 Biologic replacement of the knee: innovations and early clinical resultsJames P. StannardA9 Mizzou BioJoint Center: a translational success storyJames L. CookA10 University and industry translational partnership: from the lab to commercializationMarc JacobsA11 Beyond docking: an evolutionarily guided OneHealth approach to drug discoveryGerald J. Wyckoff, Lee Likins, Ubadah Sabbagh, Andrew SkaffA12 Challenges and opportunities for data applications in animal health: from precision medicine to precision husbandryAmado S. GuloyA13 A cloud-based programmable platform for healthHarlen D. HaysA14 Comparative oncology: One Health in actionAmy K. LeBlancA15 Companion animal diseases bridge the translational gap for human neurodegenerative diseaseJoan R. Coates, Martin L. Katz, Leslie A. Lyons, Gayle C. Johnson, Gary S. Johnson, Dennis P. O'BrienA16 Duchenne muscular dystrophy gene therapyDongsheng DuanA17 Polycystic

  18. The case for policy-relevant conservation science (United States)

    Rose, David C


    Drawing on the “evidence-based” (Sutherland et al. 2013) versus “evidence-informed” debate (Adams & Sandbrook 2013), which has become prominent in conservation science, I argue that science can be influential if it holds a dual reference (Lentsch & Weingart 2011) that contributes to the needs of policy makers whilst maintaining technical rigor. In line with such a strategy, conservation scientists are increasingly recognizing the usefulness of constructing narratives through which to enhance the influence of their evidence (Leslie et al. 2013; Lawton & Rudd 2014). Yet telling stories alone is rarely enough to influence policy; instead, these narratives must be policy relevant. To ensure that evidence is persuasive alongside other factors in a complex policy-making process, conservation scientists could follow 2 steps: reframe within salient political contexts and engage more productively in boundary work, which is defined as the ways in which scientists “construct, negotiate, and defend the boundary between science and policy” (Owens et al. 2006:640). These will both improve the chances of evidence-informed conservation policy. El Caso para la Ciencia de la Conservación con Relevancia Política Resumen A partir del debate “con base en evidencia” (Sutherland et al. 2013) versus “informado con evidencia” (Adams & Sandbrook 2013), debate que se ha vuelto prominente en la ciencia de la conservación, argumento que la ciencia puede ser influyente si mantiene una referencia dual (Lentsch & Weingart 2011) que contribuya a las necesidades de quienes hacen la política a la vez que mantiene un rigor técnico. En línea con dicha estrategia, los científicos de la conservación cada vez reconocen más la utilidad de construir narrativas con las cuales pueden mejorar la influencia de sus evidencias (Leslie et al. 2013; Lawton & Rudd 2014). Sin embargo, sólo contar historias rara vez es suficiente para influir sobre la política; en su lugar, estas

  19. Advanced basal cell carcinoma, the hedgehog pathway, and treatment options – role of smoothened inhibitors

    Directory of Open Access Journals (Sweden)

    Fecher LA


    Full Text Available Leslie A Fecher,1,3 William H Sharfman2 1Department of Internal Medicine and Dermatology, Indiana University Health Simon Cancer Center, Indianapolis, IN, USA; 2The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA, 3Department of Internal Medicine and Dermatology, University of Michigan, MI, USA Abstract: Cutaneous basal cell carcinoma (BCC is the most common human cancer and its incidence is rising worldwide. Ultraviolet radiation exposure, including tanning bed use, as well as host factors play a role in its development. The majority of cases are treated and cured with local therapies including surgery. Yet, the health care costs of diagnosis and treatment of BCCs in the US is substantial. In the United States, the cost of nonmelanoma skin cancer care in the Medicare population is estimated to be US$426 million per year. While rare, locally advanced BCCs that can no longer be controlled with surgery and/or radiation, and metastatic BCCs do occur and can be associated with significant morbidity and mortality. Vismodegib (GDC-0449, a smoothened inhibitor targeted at the hedgehog pathway, is the first US Food and Drug Association (FDA-approved agent in the treatment of locally advanced, unresectable, and metastatic BCCs. This class of agents appears to be changing the survival rates in advanced BCC patients, but appropriate patient selection and monitoring are important. Multidisciplinary assessments are essential for the optimal care and management of these patients. For some patients with locally advanced BCC, treatment with a hedgehog inhibitor may eliminate the need for an excessively disfiguring or morbid surgery. Keywords: basal cell carcinoma, hedgehog, smoothened, vismodegib, Gorlin, basal cell nevus syndrome

  20. The Montreal Lectures: 2 August - 2 October, 1944

    Energy Technology Data Exchange (ETDEWEB)

    Arsenault, J.E


    The Second World War began in the summer of 1939 and spurred atomic science in the direction of weapons development. The United Kingdom (U.K.) was far ahead until about the summer of 1941 at which time the United States (U.S.) began to have serious interest in atomic weapons. Seen from Europe, the U.S. was a greater distance from the theatre of war and was deemed to be a safer place to conduct atomic research. In addition to good research centres it also had greater financial, manpower, and material resources. Early attempts at full collaboration between the U.K. and the U.S. met with little success and this led to the formation of a joint British-Canadian atomic weapons effort in 1942, with research laboratories located in Montreal, which were well up and running by spring 1943. The Montreal laboratory (ML) initially was administered by the National Research Council (NRC) and scientific direction was provided by the U.K. The ML was the foundation from which the Canadian nuclear industry evolved to the present time. Interest in atomic weapons development by the U.S. had been greatly accelerated by the Japanese attack on Pearl Harbour on 7 December 1941. By the beginning of 1943 it was spending 10 times as much as the U.K. on atomic weapons research. From then on, the U.S. set the Allied agenda for the development of atomic weapons, in varying degrees of collaboration with the U.K. and Canada. This spending which grew to about $2B by the middle of 1945, was directed by the U.S. Army Corps of Engineers under the Manhattan Project, officially established on 13 August 1942, and led by Gen. Leslie R. Groves From 17 September 1942. (author)

  1. Hyaluronic acid gel (Juvéderm™ preparations in the treatment of facial wrinkles and folds

    Directory of Open Access Journals (Sweden)

    Inja Bogdan Allemann


    Full Text Available Inja Bogdan Allemann, Leslie BaumannUniversity of Miami Cosmetic Group, Leonard M. Miller School of Medicine, Miami Heart Institute, Miami Beach, Florida, USAAbstract: Soft tissue augmentation with temporary dermal fillers is a continuously growing field, supported by the ongoing development and advances in technology and biocompatibility of the products marketed. The longer lasting, less immunogenic and thus more convenient hyaluronic acid (HA fillers are encompassing by far the biggest share of the temporary dermal filler market. Since the approval of the first HA filler, Restylane®, there are at least 10 HA fillers that have been approved by the FDA. Not all of the approved HA fillers are available on the market, and many more are coming. The Juvéderm™ product line (Allergan, Irvine, CA, consisting of Juvéderm™ Plus and Juvéderm™ Ultra Plus, was approved by the FDA in 2006. Juvéderm™ is a bacterium-derived nonanimal stabilized HA. Juvéderm™ Ultra and Ultra Plus are smooth, malleable gels with a homologous consistency that use a new technology called “Hylacross™ technology”. They have a high concentration of cross-linked HAs, which accounts for its longevity. Juvéderm™ Ultra Plus is used for volumizing and correcting deeper folds, whereas Juvéderm™ Ultra is best for contouring and volumizing medium depth facial wrinkles and lip augmentation. Various studies have shown the superiority of the HA filler products compared with collagen fillers for duration, volume needed, and patient satisfaction. Restylane®, Perlane®, and Juvéderm™ are currently the most popular dermal fillers used in the United States.Keywords: hyaluronic acid gel, Juvéderm™, facial wrinkles, facial folds

  2. Book Reviews

    Directory of Open Access Journals (Sweden)

    Andrew Sharp


    Full Text Available - P. Voorhoeve, Tudjimah, Asrar al-insan fi maýrifa al-ruh waýl-Rahman. Tesis Djakarta, 1961. 477 blz. - F.D.K. Bosch, Alastair Lamb, Chandi Bukit Batu Pahat. Three Additional Notes. 14 pp., 2 figs., 21 pls; Monographs....(etc. No. 5, 1961. - F.D.K. Bosch, Alistair Lamb, Chandi Bukit Batu Pahat; a Report on the Excavation of an Ancient Temple in Kedah. 108 pp., 40 figs., 179 pls; Monographs on Southeast Asian Subjects No. 1, Eastern Universities Press Ltd., Singapore, 1960. - T.J. Brasser, Frederick J. Dockstader, Indian art in America - The arts and crafts of the North American Indian. New York Graphic Society, Greenwich, Mass., U.S.A. 1961. 224 pages, 70 color plates, 180 black and white illustrations. - J. Prins, Cora Vreede-De Steurs, Lýýmancipation de la femme indonýsienne. Mouton & Co, Den Haag en Parijs. 174 blz., 21 platen, 1 kaart. - Clifford Geertz, Bali, Studies in Life, Thought and Ritual; Selected Studies on Indonesia, Vol. 5. W. van Hoeve, The Hague & Bandung 1960. 368 pp. text. - Tjan Giok Bwee, D.E. Wilmott, The Chinese of Semarang: a changing minority community in Indonesia. Ithaca, New York, Cornell University Press, 1960, 366 pp. - P. Gregorius, J. de Leeuwe, Groepshuwelijk en enkelvoudig huwelijk, Uitgeverij L. Stafleu & Zoon, Leiden 1960, 136 blz. - P. van Emst, Andrew Sharp, The discovery of the Pacific Islands. Clarendon Press: Oxford University Press. Oxford 1960. 259 pp. - T. Volker, John Bastin, The changing balance of the early Southeast Asian pepper trade (Papers on Southeast Asian subjects No 1. Department of History University of Malaya in Kuala Lumpur, 1960. 60 pp. text, maps, bibliog. - W.F. Wertheim, Leslie H. Palmier, Social status and power in Java. London School of Economics Monographs on Social Anthropology, no. 20. London, 1960. 165 blz.

  3. How NASA's Space Science Support Network Can Assist DPS Members in Their Public Engagement Efforts (United States)

    Miner, E. D.; Lowes, L. L.


    In her Carl Sagan Medal lecture last year, Heidi Hammel talked of the dos and don'ts of education and public outreach efforts by DPS members. She pointed out a number of misconceptions about what does and does not constitute "good EPO" and encouraged members to consult with "the experts" if they would like to improve their EPO effectiveness and reach. She named the DPS Education and Public Outreach Officer, Larry Lebofsky, his Deputy, Lou Mayo, and the DPS Press Officer, Ellis Miner, who also co-directs NASA's Solar System Exploration EPO Forum with Leslie Lowes. NASA's Space Science Support Network has been in existence for about six years. It has been directed by DPS member Jeff Rosendhal and is now serving as a model for NASA's new Education Enterprise. Members of the Support Network are prepared to assist (and haves been assisting) space scientists throughout the US and abroad in deciding where to spend their EPO efforts most effectively. The service is provided free of cost and includes, among other services, the following: (1) helping to establish partnerships between educators and scientists, (2) helping to link scientists and professional EPO organizations, (3) helping to link scientists to national youth and community groups, (4) providing ready access to EPO electronic and hardcopy products, (5) providing advice and direction in the preparation of EPO proposals to NASA, (6) helping to maintain several national networks of EPO volunteers, (7) encouraging (at home institutions) the broadening of scientist EPO efforts, (8) maintaining self-help websites for scientists interested in EPO.

  4. Health Information Technology in Healthcare Quality and Patient Safety: Literature Review. (United States)

    Feldman, Sue S; Buchalter, Scott; Hayes, Leslie W


    , and bridge knowledge with developers would be a valuable resource allocation to consider. ©Sue S Feldman, Scott Buchalter, Leslie W. Hayes. Originally published in JMIR Medical Informatics (, 04.06.2018.

  5. Adaptive and active materials: selected papers from the ASME 2013 Conference on Smart Materials, Adaptive Structures and Intelligent Systems (SMASIS 13) (Snowbird, UT, USA, 16-18 September 2013) (United States)

    Johnson, Nancy; Naguib, Hani; Turner, Travis; Anderson, Iain; Bassiri-Gharb, Nazanin; Daqaq, Mohammed; Baba Sundaresan, Vishnu; Sarles, Andy


    The sixth annual meeting of the ASME Smart Materials, Adaptive Structures and Intelligent Systems Conference (SMASIS) was held in the beautiful mountain encircled Snowbird Resort and Conference Center in Little Cottonwood Canyon near Salt Lake City, Utah. It is the conference's objective to provide an up-to-date overview of research trends in the entire field of smart materials systems in a friendly casual forum conducive to the exchange of ideas and latest results. As each year we strive to grow and offer new experiences, this year we included special focused topic tracks on nanoscale multiferroic materials and origami engineering. The cross-disciplinary emphasis was reflected in keynote speeches by Professor Kaushik Bhattacharya (California Institute of Technology) on 'Cyclic Deformation and the Interplay between Phase Transformation and Plasticity in Shape Memory Alloys', by Professor Alison Flatau (University of Maryland at College Park) on 'Structural Magnetostrictive Alloys: The Other Smart Material', and by Dr Leslie Momoda (Director of the Sensors and Materials Laboratories, HRL Laboratories, LLC, Malibu, CA) on 'Architecturing New Functional Materials: An Industrial Perspective'. SMASIS 2013 was divided into seven symposia which span basic research, applied technological design and development, and industrial and governmental integrated system and application demonstrations. SYMP 1. Development and Characterization of Multifunctional Materials. SYMP 2. Mechanics and Behavior of Active Materials. SYMP 3. Modeling, Simulation and Control of Adaptive Systems. SYMP 4. Integrated System Design and Implementation. SYMP 5. Structural Health Monitoring. SYMP 6. Bioinspired Smart Materials and Systems. SYMP 7. Energy Harvesting. Authors of selected papers in the materials areas (symposia 1, 2, and 6) as well as energy harvesting (symposium 7) were invited to write a full journal article on their presentation topic for publication in this special issue of Smart

  6. On the ecological context of the earliest human settlements in Europe: Resource availability and competition intensity in the carnivore guild of Barranco León-D and Fuente Nueva-3 (Orce, Baza Basin, SE Spain) (United States)

    Rodríguez-Gómez, Guillermo; Palmqvist, Paul; Rodríguez, Jesús; Mateos, Ana; Martín-González, Jesús A.; Espigares, M. Patrocinio; Ros-Montoya, Sergio; Martínez-Navarro, Bienvenido


    With an age of ∼1.4 Ma, the Early Pleistocene archaeopaleontological sites of Barranco León and Fuente Nueva-3 (Orce, Baza Basin, SE Spain) provide the oldest evidence on human presence in Western Europe, including the finding of a deciduous tooth of Homo sp., huge lithic assemblages of Oldowan tradition and abundant cut-marks on large mammal bones. Here we use a mathematical approach based on Leslie matrices to quantify for the large mammal species preserved at the sites the biomass of primary consumers available, the distribution of meat resources among the secondary consumers and the competition intensity within the carnivore guild. The results obtained show a community of large mammals with a high diversity of secondary consumers that would satisfy slightly less than half of their dietary requirements under optimal ecological conditions. In the case of Homo sp., and considering that flesh resources were obtained through the scavenging of ungulate carcasses, the model indicates that the ecosystems of the basin could hold 10-14 individuals per 100 km2 during a year, a value that is close to the mean population density of recent hunter-gatherers. These density estimates decrease slightly when a mixed hunting-scavenging strategy is considered and even more in the case of a strict hunting behavior. In addition, the value of the species competition index obtained for Homo sp. is among the lowest of the carnivore guild. These results suggest that the hominin populations that inhabited Southeast Spain during the Early Pleistocene behaved more as opportunistic scavengers than as active predators.

  7. Evaluation of sleep profile in schizophrenia patients treated with extended-release paliperidone: an open-label prospective study in Southeast Asia

    Directory of Open Access Journals (Sweden)

    Kongsakon R


    Full Text Available Ronnachai Kongsakon,1 Nuntika Thavichachart,2 Ka Fai Chung,3 Leslie Lim,4 Beverly Azucena,5 Elizabeth Rondain,6 Benson Go,7 Fe Costales,8 Osot Nerapusee9 1Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Department of Medicine, Division of Psychiatry, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand; 3Department of Psychiatry, University of Hong Kong, Hong Kong, People’s Republic of China; 4Department of Psychiatry, Singapore General Hospital, Singapore; 5National Center for Mental Health, Mandaluyong, Philippines; 6Makati Medical Center, Makati, Philippines; 7Northern Mindanao Medical Center, Cagayan De Oro, Misamis Oriental, Philippines; 8Perpetual Succour Hospital, Cebu, Philippines; 9Medical Affairs, Janssen‑Cilag, Bangkok, Thailand Objective: To evaluate the effect of 6 months of treatment with paliperidone extended-release (ER tablets on the sleep profile of patients with schizophrenia.Methods: A total of 984 patients meeting the The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV criteria for schizophrenia who switched their antipsychotic to paliperidone ER were recruited from 61 sites in five countries in Southeast Asia. We recorded patient demographics and assessed sleep quality and daytime drowsiness using visual analog scales.Results: Approximately 70% of patients completed the 6-month study. After the use of paliperidone ER, patients reported significantly better sleep quality (76.44 vs 65.48; p<0.001 and less daytime drowsiness compared with their baseline value (23.18 vs 34.22; p<0.001. Factors predicting sleep profile improvement were completion of the study and higher baseline Positive and Negative Syndrome Scale scores.Conclusion: Paliperidone ER can help schizophrenia patients to improve sleep quality and reduce daytime drowsiness; this was seen especially in the patients who completed the 6-month

  8. Bioprinting of Micro-Organ Tissue Analog for Drug Metabolism Study (United States)

    Sun, Wei

    An evolving application of tissue engineering is to develop in vitro 3D cell/tissue models for drug screening and pharmacological study. In order to test in space, these in vitro models are mostly manufactured through micro-fabrication techniques and incorporate living cells with MEMS or microfluidic devices. These cell-integrated microfluidic devices, or referred as microorgans, are effective in furnishing reliable and inexpensive drug metabolism and toxicity studies [1-3]. This paper will present an on-going research collaborated between Drexel University and NASA JSC Radiation Physics Laboratory for applying a direct cell printing technique to freeform fabrication of 3D liver tissue analog in drug metabolism study. The paper will discuss modeling, design, and solid freeform fabrication of micro-fluidic flow patterns and bioprinting of 3D micro-liver chamber that biomimics liver physiological microenvironment for enhanced drug metabolization. Technical details to address bioprinting of 3D liver tissue analog, integration with a microfluidic device, and basic drug metabolism study for NASA's interests will presented. 1. Holtorf H. Leslie J. Chang R, Nam J, Culbertson C, Sun W, Gonda S, "Development of a Three-Dimensional Tissue-on-a-Chip Micro-Organ Device for Pharmacokinetic Analysis", the 47th Annual Meeting of the American Society for Cell Biology, Washington, DC, December 1-5, 2007. 2. Chang, R., Nam, J., Culbertson C., Holtorf, H., Jeevarajan, A., Gonda, S. and Sun, W., "Bio-printing and Modeling of Flow Patterns for Cell Encapsulated 3D Liver Chambers For Pharmacokinetic Study", TERMIS North America 2007 Conference and Exposition, Westin Harbour Castle, Toronto, Canada, June 13-16, 2007. 3.Starly, B., Chang, R., Sun, W., Culbertson, C., Holtorf, H. and Gonda, S., "Bioprinted Tissue-on-chip Application for Pharmacokinetic Studies", Proceedings of World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, PA, USA, April 24-27, 2006.

  9. Integrating temperature-dependent life table data into a matrix projection model for Drosophila suzukii population estimation.

    Directory of Open Access Journals (Sweden)

    Nik G Wiman

    Full Text Available Temperature-dependent fecundity and survival data was integrated into a matrix population model to describe relative Drosophila suzukii Matsumura (Diptera: Drosophilidae population increase and age structure based on environmental conditions. This novel modification of the classic Leslie matrix population model is presented as a way to examine how insect populations interact with the environment, and has application as a predictor of population density. For D. suzukii, we examined model implications for pest pressure on crops. As case studies, we examined model predictions in three small fruit production regions in the United States (US and one in Italy. These production regions have distinctly different climates. In general, patterns of adult D. suzukii trap activity broadly mimicked seasonal population levels predicted by the model using only temperature data. Age structure of estimated populations suggest that trap and fruit infestation data are of limited value and are insufficient for model validation. Thus, we suggest alternative experiments for validation. The model is advantageous in that it provides stage-specific population estimation, which can potentially guide management strategies and provide unique opportunities to simulate stage-specific management effects such as insecticide applications or the effect of biological control on a specific life-stage. The two factors that drive initiation of the model are suitable temperatures (biofix and availability of a suitable host medium (fruit. Although there are many factors affecting population dynamics of D. suzukii in the field, temperature-dependent survival and reproduction are believed to be the main drivers for D. suzukii populations.

  10. The Physics of NASCAR (United States)

    Leslie-Pelecky, Diandra


    A group of racecars piloted by the best drivers in NASCAR are turning a corner. Without warning, one of the cars suddenly hits the outside wall. There were no engine failures, no flat tires, and none of the cars touched so what happened? Understanding and being able to apply physics is a necessary (but far from sufficient) condition for winning races.ootnotetextDiandra Leslie-Pelecky, The Physics of NASCAR (Dutton, New York City, 2008). Every competitive race team has a technical staff involved in everything from applied engineering to basic research and development. Aerodynamicists, chemical engineers, statisticians and physicists have become important participants in the high-stakes world of motorsports. Although some drivers have engineering degrees, even those without them have developed a highly intuitive understanding of physics -- you don't keep your job long without a working knowledge of Newton's Laws of Motion. The inherent science in NASCAR is of interest at many levels, from the fan who wants to understand changes made to the car at pit stops to nanomaterials researchers looking for new ways to make racing simultaneously faster and safer. This presentation will introduce some of the fascinating physics of NASCAR and give teachers some ideas to use in the classroom. I'll touch on a range of topics from: how computational fluid dynamics is used to address the aerodynamic changes that challenge the driver by making his car behave differently around every corner; how advanced materials such as energy-absorbing foams have made racing significantly safer; and how nanoparticles may be able to keep engines from overheating despite running at 9500 rpm for three or four hours. Finally, I'll explore NASCAR, its teams and its sponsors are helping address the challenge of getting people interest math and science.

  11. Tay-Sachs disease: current perspectives from Australia

    Directory of Open Access Journals (Sweden)

    Lew RM


    Full Text Available Raelia M Lew,1,7 Leslie Burnett,2,3,4 Anné L Proos,2 Martin B Delatycki5,6 1Department of Obstetrics and Gynecology, QEII Research Institute for Mothers and Infants, The University of Sydney, Australia; 2NSW Health Pathology North, Royal North Shore Hospital, St Leonards, Australia; 3SEALS, Prince of Wales Hospital, Randwick, Australia; 4Sydney Medical School-Northern, Royal North Shore Hospital E25, University of Sydney, Sydney, Australia; 5Department of Clinical Genetics, Austin Health, Heidelberg, Australia; 6Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Parkville, Australia; 7Department of Obstetrics and Gynaecology, Dentistry and Health Sciences, Faculty of Medicine, The University of Melbourne, Melbourne, Australia Abstract: Tay-Sachs disease (TSD is a fatal, recessively inherited neurodegenerative condition of infancy and early childhood. Although rare in most other populations, the carrier frequency is one in 25 in Ashkenazi Jews. Australian high-school-based TSD preconception genetic screening programs aim to screen, educate, and optimize reproductive choice for participants. These programs have demonstrated high uptake, low psychological morbidity, and have been shown to result in fewer than expected Jewish TSD-affected births over 18 years of operation. The majority of Jewish individuals of reproductive age outside of the high school screening program setting in Australia have not accessed screening. Recent recommendations advocate supplementing the community high school screening programs with general practitioner- and obstetrician-led genetic screening of Ashkenazi Jewish individuals for TSD and other severe recessive diseases for which this group is at risk. Massively parallel DNA sequencing is expected to become the testing modality of choice over the coming years. Keywords: Tay-Sachs disease, genetic screening, Australia

  12. Patient identified needs for chronic obstructive pulmonary disease versus billed services for care received

    Directory of Open Access Journals (Sweden)

    Jill Heins-Nesvold


    Full Text Available Jill Heins-Nesvold1, Angeline Carlson2, Leslie King-Schultz3, Kenneth E Joslyn41American Lung Association of Minnesota, St. Paul, MN, USA; 2Data Intelligence Consultants, LLC, Eden Prairie, MN, USA; 3Mayo Medical School, Rochester, MN, USA; 4Medica Health Plan, Minnetonka, MN, USAAbstract: The American Lung Association of Minnesota (ALAMN was granted access to a 2004 administrative claims data from an upper mid-Western, independent practice association model health plan. Claims information, including demographics, prevalence, medication and oxygen therapy, and health care utilization, was extracted for 7,782 patients with COPD who were 40 years of age and older. In addition, ALAMN conducted a survey of 1,911 patients from Minnesota diagnosed with COPD. The survey queried the patients about demographics, treatment, medications, limitations, wants, and needs. This article compares and contrasts the information gained through the health plan administrative claims database with the findings from the COPD patient survey in areas of age, gender, types of provider primarily responsible for COPD care, spirometry use, medication therapy, pulmonary rehabilitation, oxygen therapy, and health care utilization. Primary care practitioners provided a majority of the COPD-related care. The claims evidence of spirometry use was 16%–62% of COPD patients had claims evidence of COPD-related medications. 25% of patients reported, and 23% of patients had claims evidence of, a hospitalization during the observation year. 16% of patients reported using pulmonary rehabilitation programs. The results indicate there is an opportunity to improve COPD diagnosis and management.Keywords: chronic obstructive pulmonary disease, oxygen therapy, medication therapy, spirometry, chronic care, assessment

  13. First study on domestic dog ecology, demographic structure and dynamics in Bamako, Mali. (United States)

    Mauti, Stephanie; Traoré, Abdallah; Sery, Amadou; Bryssinckx, Ward; Hattendorf, Jan; Zinsstag, Jakob


    For the planning of an effective dog mass vaccination campaign against rabies in Africa, it is crucial to know more about the dog population. In this paper we describe for the first time the dog ecology, demographic structure and population dynamics of a domestic dog population in Bamako, Mali. In 2010 and 2011, we visited 2956 randomly selected compounds. Questionnaire data was collected on the compound and household level and on each dog individually. Dog-owning households were followed every six months during one (dog-owning households identified in 2011) or two years (dog-owning households identified in 2010) for the successive collection of dog demography data. We recorded 379 dogs in 279 compounds. The dog human ratio was estimated at 1:121, and the extrapolation of the domestic dog population in Bamako results in an estimate of 14 906 dogs (95% CI 13 041-17 037). The female male ratio was 1:2.8. A high proportion of young dogs was found as a result of a high turnover rate in the population. Mortality within the first year of life was high, and dogs had a life expectancy at birth of 2.5 years. Using a Leslie matrix, we estimated the annual dog population growth to be 20%. Christians were more likely to be dog owners than Muslims. Another factor favouring dog ownership was belonging to the ethnic group of Bobo or Malinke. Dogs were mainly used as watchdogs and fed with household leftovers and garbage. They were most often obtained and given away without remuneration. This work contributes vital information towards planning effective and sustainable dog rabies control programmes for the district of Bamako. Due to the high turnover rate, we recommend repeated mass-vaccination campaigns of at least 70% of the owned dogs at yearly intervals. In addition, dog-owners need to be educated on good dog management. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. [Awareness of health co-benefits of carbon emissions reduction in urban residents in Beijing: a cross-sectional survey]. (United States)

    Gao, J H; Zhang, Y; Wang, J; Chen, H J; Zhang, G B; Liu, X B; Wu, H X; Li, J; Li, J; Liu, Q Y


    Objective: To understand the awareness of the health co-benefits of carbon emission reduction in urban residents in Beijing and the influencing factors, and provide information for policy decision on carbon emission reduction and health education campaigns. Methods: Four communities were selected randomly from Fangshan, Haidian, Huairou and Dongcheng districts of Beijing, respectively. The sample size was estimated by using Kish-Leslie formula for descriptive analysis. 90 participants were recruited from each community. χ (2) test was conducted to examine the associations between socio-demographic variables and individuals' awareness of the health co-benefits of carbon emission reduction. Ordinal logistic regression analysis was performed to investigate the factors influencing the awareness about the health co-benefits. Results: In 369 participants surveyed, 12.7 % reported they knew the health co-benefits of carbon emission reduction. The final logistic regression analysis revealed that age ( OR =0.98), attitude to climate warming ( OR =0.72) and air pollution ( OR =1.59), family monthly average income ( OR =1.27), and low carbon lifestyle ( OR =2.36) were important factors influencing their awareness of the health co-benefits of carbon emission reduction. Conclusion: The awareness of the health co-benefits of carbon emissions reduction were influenced by people' socio-demographic characteristics (age and family income), concerns about air pollution and climate warming, and low carbon lifestyle. It is necessary to take these factors into consideration in future development and implementation of carbon emission reduction policies and related health education campaigns.

  15. The Montreal Lectures: 2 August - 2 October, 1944

    International Nuclear Information System (INIS)

    Arsenault, J.E.


    The Second World War began in the summer of 1939 and spurred atomic science in the direction of weapons development. The United Kingdom (U.K.) was far ahead until about the summer of 1941 at which time the United States (U.S.) began to have serious interest in atomic weapons. Seen from Europe, the U.S. was a greater distance from the theatre of war and was deemed to be a safer place to conduct atomic research. In addition to good research centres it also had greater financial, manpower, and material resources. Early attempts at full collaboration between the U.K. and the U.S. met with little success and this led to the formation of a joint British-Canadian atomic weapons effort in 1942, with research laboratories located in Montreal, which were well up and running by spring 1943. The Montreal laboratory (ML) initially was administered by the National Research Council (NRC) and scientific direction was provided by the U.K. The ML was the foundation from which the Canadian nuclear industry evolved to the present time. Interest in atomic weapons development by the U.S. had been greatly accelerated by the Japanese attack on Pearl Harbour on 7 December 1941. By the beginning of 1943 it was spending 10 times as much as the U.K. on atomic weapons research. From then on, the U.S. set the Allied agenda for the development of atomic weapons, in varying degrees of collaboration with the U.K. and Canada. This spending which grew to about $2B by the middle of 1945, was directed by the U.S. Army Corps of Engineers under the Manhattan Project, officially established on 13 August 1942, and led by Gen. Leslie R. Groves From 17 September 1942. (author)

  16. Radiographer and radiologist perception error in reporting double contrast barium enemas: A pilot study

    International Nuclear Information System (INIS)

    Booth, Alison M.; Mannion, Richard A.J.


    Purpose: The practice of radiographers performing double contrast barium enemas (DCBE) is now widespread and in many centres the radiographer's opinion is, at least, contributing to a dual reporting system [Bewell J, Chapman AH. Radiographer performed barium enemas - results of a survey to assess progress. Radiography 1996;2:199-205; Leslie A, Virjee JP. Detection of colorectal carcinoma on double contrast barium enema when double reporting is routinely performed: an audit of current practice. Clin Radiol 2001;57:184-7; Culpan DG, Mitchell AJ, Hughes S, Nutman M, Chapman AH. Double contrast barium enema sensitivity: a comparison of studies by radiographers and radiologists. Clin Radiol 2002;57:604-7]. To ensure this change in practice does not lead to an increase in reporting errors, this study aimed to compare the perception abilities of radiographers with those of radiologists. Methods: Three gastro-intestinal (GI) radiographers and three consultant radiologists independently reported on a selection of 50 DCBE examinations, including the level of certainty in their comments for each examination. A blinded comparison of the results with an independent 'standard report' was recorded. Results: The results demonstrate there was no significant difference in perception error for any of the levels of certainty, for single reporting, for double reading by a radiographer/radiologist or by two radiologists. Conclusions: The study shows that radiographers can perceive abnormalities on DCBE at similar sensitivities and specificities as radiologists. While the participants in the study may be typical of a district general hospital, the nature of the study gives it limited external validity. As a pilot, the results demonstrate that, with slight modification, the methodology could be used for a larger study

  17. Collision probability in two-dimensional lattice by ray-trace method and its applications to cell calculations

    International Nuclear Information System (INIS)

    Tsuchihashi, Keichiro


    A series of formulations to evaluate collision probability for multi-region cells expressed by either of three one-dimensional coordinate systems (plane, sphere and cylinder) or by the general two-dimensional cylindrical coordinate system is presented. They are expressed in a suitable form to have a common numerical process named ''Ray-Trace'' method. Applications of the collision probability method to two optional treatments for the resonance absorption are presented. One is a modified table-look-up method based on the intermediate resonance approximation, and the other is a rigorous method to calculate the resonance absorption in a multi-region cell in which nearly continuous energy spectra of the resonance neutron range can be solved and interaction effect between different resonance nuclides can be evaluated. Two works on resonance absorption in a doubly heterogeneous system with grain structure are presented. First, the effect of a random distribution of particles embedded in graphite diluent on the resonance integral is studied. Next, the ''Accretion'' method proposed by Leslie and Jonsson to define the collision probability in a doubly heterogeneous system is applied to evaluate the resonance absorption in coated particles dispersed in fuel pellet of the HTGR. Several optional models are proposed to define the collision rates in the medium with the microscopic heterogeneity. By making use of the collision probability method developed by the present study, the JAERI thermal reactor standard nuclear design code system SRAC has been developed. Results of several benchmark tests for the SRAC are presented. The analyses of critical experiments of the SHE, DCA, and FNR show good agreement of critical masses with their experimental values. (J.P.N.)

  18. Are there specific metacognitive processes associated with anxiety disorders in youth?

    Directory of Open Access Journals (Sweden)

    Terri Landon Bacow


    Full Text Available Terri Landon Bacow1, Jill Ehrenreich May2, Leslie R Brody3, Donna B Pincus41Mount Sinai School of Medicine, New York City, NY, USA; 2Department of Psychology, University of Miami, FL, USA; 3Department of Psychology, 4Center for Anxiety and Related Disorders, Boston University, MA, USAAbstract: While Wells’ metacognitive model of generalized anxiety disorder (GAD posits that certain metacognitive processes, such as negative meta-worry (negative beliefs about worry, are more strongly associated with symptoms of GAD than other anxiety disorders in adults, research has yet to determine whether the same pattern is true for younger individuals. We examined the relationship between several metacognitive processes and anxiety disorder diagnostic status in a sample of 98 youth aged 7–17 years. Twenty youth with GAD were compared with similarly sized groups of youth with obsessive-compulsive disorder (OCD, n = 18, social phobia (SOC, n = 20, separation anxiety disorder (SAD, n = 20, and healthy controls who were not patients (NONP, n = 20 using a self-report measure of metacognition adapted for use with young people in this age range (Metacognitions Questionnaire for Children. Contrary to expectations, only one specific metacognitive process was significantly associated with an anxiety disorder diagnosis, in that the controls endorsed a greater degree of cognitive monitoring (self-reported awareness of one’s thoughts than those with SAD. In addition, there was a trend indicating that nonpatients scored higher than youth with GAD on this scale. These surprising results suggest potentially differing patterns in the relationships between symptoms and metacognitive awareness in anxious youth, depending on the type of anxiety disorder presentation.Keywords: metacognition, childhood, adolescence, anxiety, diagnosis

  19. Public health implications of lead poisoning in backyard chickens and cattle: four cases

    Directory of Open Access Journals (Sweden)

    Roegner A


    Full Text Available Amber Roegner,1 Federico Giannitti,2 Leslie W Woods,2 Asli Mete,2 Birgit Puschner1,2 1Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA, USA; 2California Animal Health and Food Safety Laboratory System, School of Veterinary Medicine, University of California, Davis, CA, USA Abstract: Lead intoxication in livestock has historically been associated with cattle turned out to pasture and accidental ingestion of lead from drinking crankcase oil, licking grease from machinery, chewing on plumbing or batteries, or drinking water contaminated from leaching materials. Even with the decrease in manufactured items produced with lead, contaminants persist in the landscape and may enter the food supply through animal products. Changing patterns of open range herds moving to new pasture and the increased popularity of urban/suburban backyard chickens or other livestock necessitates public awareness about the clinical signs of lead intoxication, the potential for subclinical animals, public health concerns, particularly for exposure in children, and testing options available. Cases of lead intoxication in livestock demand a thorough case work-up to identify all sources of lead, address subclinical cases, evaluate risk to consumers, and make management suggestions for future prevention. We discuss four recent cases of confirmed lead poisoning in backyard chickens and open range cattle and assess the public health implications therein. Taken as a whole and considering the potential of the remaining herd or flock to be affected without necessarily showing signs, public health officials and veterinarians should be prepared to advise clients on case work-up and management and prevention considerations. Backyard chickens and cattle may not present for suspected lead poisoning as in several of the cases discussed herein yet may still contain concerning tissue or blood levels. The authors believe increased

  20. Mixing times towards demographic equilibrium in insect populations with temperature variable age structures. (United States)

    Damos, Petros


    In this study, we use entropy related mixing rate modules to measure the effects of temperature on insect population stability and demographic breakdown. The uncertainty in the age of the mother of a randomly chosen newborn, and how it is moved after a finite act of time steps, is modeled using a stochastic transformation of the Leslie matrix. Age classes are represented as a cycle graph and its transitions towards the stable age distribution are brought forth as an exact Markov chain. The dynamics of divergence, from a non equilibrium state towards equilibrium, are evaluated using the Kolmogorov-Sinai entropy. Moreover, Kullback-Leibler distance is applied as information-theoretic measure to estimate exact mixing times of age transitions probabilities towards equilibrium. Using empirically data, we show that on the initial conditions and simulated projection's trough time, that population entropy can effectively be applied to detect demographic variability towards equilibrium under different temperature conditions. Changes in entropy are correlated with the fluctuations of the insect population decay rates (i.e. demographic stability towards equilibrium). Moreover, shorter mixing times are directly linked to lower entropy rates and vice versa. This may be linked to the properties of the insect model system, which in contrast to warm blooded animals has the ability to greatly change its metabolic and demographic rates. Moreover, population entropy and the related distance measures that are applied, provide a means to measure these rates. The current results and model projections provide clear biological evidence why dynamic population entropy may be useful to measure population stability. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Ámbito de aplicación del nuevo sistema laboral procesal

    Directory of Open Access Journals (Sweden)

    Rosina Rossi Albert


    Full Text Available Oscar Ermida, mi amigo desde hace veintiocho años; mi maestro desde entonces y en el re-descubrir su pensamiento, para siempre.El nuevo sistema laboral procesal – como le gustaba llamarlo – es, en sí mismo, un homenaje a él. Lo imaginó desde el seno del Derecho del Trabajo, instaló la piedra fundamental, fue artífice principal en su elaboración tramo a tramo, lo defendió antes y después de la aprobación legislativa.Lo siguió soñando hasta sus últimos días, hasta sus últimas fuerzas, como un reducto de esperanza de hacer realidad la dignidad del hombre- trabajador.Un día para recordar: el 12.6.2007 a su instancia , reunió al Ministro de la Suprema Corte de Justicia Dr. Leslie Van Rompaey con el Sub Secretario del Ministerio de Trabajo y de la Seguridad Social Dr. Jorge Bruni. En la ocasión, puso la piedra fundamental. Pocos días después, el 20.7.2007 la Suprema Corte de Justicia dictó la Resolución n . 381/2007 instalando la comisión redactora de un anteproyecto de ley de abreviación de los juicios laborales, que finalmente fue la ley 18.572.El nuevo sistema laboral procesal. La labor de interpretación en el nuevo sistema laboral procesal. Conflicto, proceso y jurisdicción. Análisis de la ley 18.572. Brevísimas conclusiones

  2. Materials at 200 mph: Making NASCAR Faster and Safer (United States)

    Leslie-Pelecky, Diandra


    You cannot win a NASCAR race without understanding science.ootnotetextDiandra Leslie-Pelecky, The Physics of NASCAR (Dutton, New York City, 2008). Materials play important roles in improving performance, as well as ensuring safety. On the performance side, NASCAR limits the materials race car scientists and engineers can use to limit ownership costs. `Exotic metals' are not allowed, so controlling microstructure and nanostructure are important tools. Compacted Graphite Iron, a cast iron in which magnesium additions produce interlocking microscale graphite reinforcements, makes engine blocks stronger and lighter. NASCAR's new car design employs a composite called Tegris^TM that has 70 percent of the strength of carbon fiber composites at about 10 percent of the cost. The most important role of materials in racing is safety. Drivers wear firesuits made of polymers that carbonize (providing thermal protection) and expand (reducing oxygen access) when heated. Catalytic materials originally developed for space-based CO2 lasers filter air for drivers during races. Although materials help cars go fast, they also help cars slow down safely---important because the kinetic energy of a race car going 180 mph is nine times greater than that of a passenger car going 60 mph. Energy-absorbing foams in the cars and on the tracks control energy dissipation during accidents. To say that most NASCAR fans (and there are estimated to be 75 million of them) are passionate about their sport is an understatement. NASCAR fans understand that science and engineering are integral to keeping their drivers safe and helping their teams win. Their passion for racing gives us a great opportunity to share our passion for science with them. NASCAR^ is a registered trademark of the National Association for Stock Car Auto Racing, Inc. Tegris^TM is a trademark of Milliken & Company.

  3. Algebraic Theory of Linear Viscoelastic Nematodynamics

    International Nuclear Information System (INIS)

    Leonov, Arkady I.


    This paper consists of two parts. The first one develops algebraic theory of linear anisotropic nematic 'N-operators' build up on the additive group of traceless second rank 3D tensors. These operators have been implicitly used in continual theories of nematic liquid crystals and weakly elastic nematic elastomers. It is shown that there exists a non-commutative, multiplicative group N 6 of N-operators build up on a manifold in 6D space of parameters. Positive N-operators, which in physical applications hold thermodynamic stability constraints, do not generally form a subgroup of group N 6 . A three-parametric, commutative transversal-isotropic subgroup S 3 subset of N 6 of positive symmetric nematic operators is also briefly discussed. The special case of singular, non-negative symmetric N-operators reveals the algebraic structure of nematic soft deformation modes. The second part of the paper develops a theory of linear viscoelastic nematodynamics applicable to liquid crystalline polymer. The viscous and elastic nematic components in theory are described by using the Leslie-Ericksen-Parodi (LEP) approach for viscous nematics and de Gennes free energy for weakly elastic nematic elastomers. The case of applied external magnetic field exemplifies the occurrence of non-symmetric stresses. In spite of multi-(10) parametric character of the theory, the use of nematic operators presents it in a transparent form. When the magnetic field is absent, the theory is simplified for symmetric case with six parameters, and takes an extremely simple, two-parametric form for viscoelastic nematodynamics with possible soft deformation modes. It is shown that the linear nematodynamics is always reducible to the LEP-like equations where the coefficients are changed for linear memory functionals whose parameters are calculated from original viscosities and moduli

  4. Ciencia Cognitiva, Teoría de la Mente y autismo

    Directory of Open Access Journals (Sweden)

    Isabel Gómez Echeverry


    Full Text Available Este artículo toma como referencia los aportes de la Psicología Cognitiva en el estudio del autismo. En primera instancia se realiza una descripción de los conceptos de representaciones mentales (Johnson-Laird 1983, 1987, 1990, Norman, 1983 y la metáfora del cerebro como computador (Tulving, 1937, 1950. Posteriormente, se ahonda en el concepto de teoría de la mente tomando como referencia los estudios iniciales de Premack y Woodruff (1978, Rivière (1987, 1991a, 1991b. Se describe la relación entre teoría de la mente y autismo, partiendo de los estudios de Karner (1943. Wing (1981. Desde la teoría-teoría, existen varias teorías psicológicas que tratan de explicar el fenómeno del autismo: la de la Ceguera Mental (Barón-Cohen, Leslie y Frith, 1985, la del Debilitamiento de la Coherencia Central Frith (2003, y la de la Disfunción Ejecutiva (Russel, 2000 y Ozonoff, 2000. Otra de las teorías es la Hobson (1995, quien plantea que los déficits cognitivos y sociales en el autismo son de naturaleza afectiva. Finalmente, es importante destacar que las habilidades deficientes en el autismo son destrezas muy complejas, que dependen no sólo de procesos de planificación y ejecución y de inferencias mentalistas, sino de una coordinación de muchas funciones que actúan simultáneamente.

  5. Exploring the population implications of male preference when the sex probabilities at birth can be altered

    Directory of Open Access Journals (Sweden)

    Frank T Denton


    Full Text Available Objective: The paper explores the population effects of male preference stopping rules and of alternative combinations of fertility rates and male-biased birth sex ratios. Methods: The 'laboratory' is a closed, stable population with five age groups and a dynamic process represented by a compact Leslie matrix. The new element is sex-selective abortion. We consider nine stopping rules, one with no male preference, two with male preference but no abortion, and six with male preference and the availability of abortion to achieve a desired number of male births. We calculate the probability distribution over the number of births and number of male births for each rule and work out the effects at the population level if the rule is adopted by all women bearing children. We then assess the impact of alternative combinations of fertility rates and male-biased sex ratios on the population. Results: In the absence of sex-selective abortion, stopping rules generally have no effect on the male/female birth proportions in the population, although they can alter the fertility rate, age distribution, and rate of growth. When sex-selective abortion is introduced the effect on male/female proportions may be considerable, and other effects may also be quite different. The contribution of this paper is the quantification of effects that might have been predictable in general but which require model-based calculations to see how large they can be. As the paper shows, they can in fact be very large: a population in which sex-selective abortion is widely practised can look quite different from what it would otherwise be.

  6. Projected demographic composition of the United States population of people living with diagnosed HIV. (United States)

    Hood, Julia E; Golden, Matthew R; Hughes, James P; Goodreau, Steven M; Siddiqi, Azfar-E-Alam; Buskin, Susan E; Hawes, Stephen E


    The transformation of HIV from a fatal disease to lifelong disease has resulted in an HIV-infected population that is growing and aging, placing new and increasing demands on public programs and health services. We used National HIV Surveillance System and US census data to project the demographic composition of the population of people living with diagnosed HIV (PLWDH) in the United States through 2045. The input parameters for the projections include: (1) census projections, (2) number of people with an existing HIV diagnosis in 2013, (3) number of new HIV diagnoses in 2013, and (4) death rate within the PLWDH population in 2013. Sex-, risk group-, and race-specific projections were estimated through an adapted Leslie Matrix Model for age-structured populations. Projections for 2013-2045 suggest that the number of PLWDH in the U.S. will consistently grow, from 917,294 to 1,232,054, though the annual growth rate will slow from 1.8% to 0.8%. The number of PLWDH aged 55 years and older will increase from 232,113 to 470,221. The number of non-Hispanic (NH) African Americans/Blacks and Hispanics is projected to consistently grow, shifting the racial/ethnic composition of the US PLWDH population from 32 to 23% NH-White, 42 to 38% NH-Black, and 20-32% Hispanic between 2013 and 2045. Given current trends, the composition of the PLWDH population is projected to change considerably. Public health practitioners should anticipate large shifts in the age and racial/ethnic structure of the PLWDH population in the United States.

  7. [Population demography in Rhinella arenarum (Anura: Bufonidae) and Physalaemus biligonigerus (Anura: Leiuperidae) in agroecosystems in the province of Córdoba, Argentina]. (United States)

    Bionda, Clarisa; Lajmanovich, Rafael; Salas, Nancy; Martino, Adolfo; di Tada, Ismael


    The advancing agricultural frontier has led to an important loss of natural habitats, with significant consequences for biodiversity. The demography for two species of anurans, Physalaemus biligonigerus and Rhinella arenarum, both associated with agricultural systems in the central region of the C6rdoba Province, were analyzed and compared in this study. Four sites were sampled: three agroecosystems with different alteration degrees (C1, C2 and SM1) and a fourth site not cultivated (SM2). The sampling was conducted during two reproductive periods, from September 2008 to April 2009 and September 2009 to April 2010. Individuals were captured using live pitfall traps for the metamorphic, juveniles and adults; and visual encounter survey, for the capture of eggs and larvae. With the abundance data, the survival for each age class was estimated using the KNM method (Kiritani Nakasuki Manly). With survival rates and fertility population, Leslie matrices were elaborated to obtain a quantitative projection of the population size. Altered environments showed lower eggs and larvae survival. Population projections were favorable in the site SM2 and were less favorable and a tendency to extinction, in sites dominated by crops. This study showed that the agroecosystems of this region are possibly inhospitable environments for reproduction and survival of the species studied. The aquatic stages in the life cycle of both species would be the more affected, since water bodies deterioration is present or may occur in those areas. We can recognize species-specific effects of agricultural ecosystems; P. biligonigerus was the most affected species, possibly because of their life histories and habitat requirements. We suggested that environmental degradation caused by the cropland in the central region of Argentina would impact on the demographics of the anuran populations in the area.

  8. Effect of pasteurization on the decay of Mycobacterium bovis in milk cream

    Directory of Open Access Journals (Sweden)

    Livia de Andrade Rodrigues


    Full Text Available Milk cream must be pasteurized in order to be sold in Brazil. However, there are no specific legal requirements for this product, and producers set their own pasteurization parameters using the ones approved for milk as a reference. Considering that fat protects bacteria from heat, that no thermal inactivation studies have been performed on Mycobacterium bovis present in cream, and that bovine tuberculosis is endemic in Brazil, the aim of this study was to evaluate the inactivation of M. bovis in milk cream subjected to commercial parameters of pasteurization. Milk cream samples were contaminated and pasteurized in a water bath at 75, 80, 85, and 90°C for 5 and 15 s. M. bovis cells were plated onto Stonebrink-Leslie medium, incubated at 36°C for 45 days, and quantified; the result was expressed in log CFU mL-1. The fat content of the samples ranged from 34% to 37% and the average initial load of M. bovis was 8.0 Log CFU mL-1. The average decay of the M. bovis populations was 4.0, 4.3, 4.9 and 6.7 log CFU mL-1 when the cream was incubated for 15 sec at 75, 80, 85 and 90°C, respectively, showing that the efficiency of the heat treatment was improved by increasing the temperature of the process. Given the lipophilic nature of M. bovis, the cream should be subjected to more intense parameters of pasteurization than those applied to milk.

  9. Addressing the need for rapid treatment of agitation in schizophrenia and bipolar disorder: focus on inhaled loxapine as an alternative to injectable agents

    Directory of Open Access Journals (Sweden)

    Citrome L


    Full Text Available Leslie CitromeDepartment of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, NY, USAAbstract: Agitation (excessive motor or verbal activity can be associated with schizophrenia or bipolar mania, and can further escalate into aggressive behavior and potentially lead to injuries in patients and staff. Medications used to treat agitation include antipsychotics and benzodiazepines, usually administered intramuscularly when rapid action is desired. Loxapine, a first-generation antipsychotic, has recently been reformulated into an inhaled powder that allows for direct administration to the lungs, resulting in rapid absorption into the systemic circulation. Administered via a single-use device, inhaled loxapine was tested in randomized controlled trials in agitation associated with schizophrenia or bipolar mania; doses of 5 mg and 10 mg were found to be efficacious, with an apparent dose response. In the Phase III studies, number needed to treat versus placebo for a ≥40% reduction from baseline on the Positive and Negative Syndrome Scale – Excited Component (PANSS-EC at 2 hours was three for patients with bipolar disorder, and five for 5 mg and four for 10 mg for patients with schizophrenia, with effect sizes comparable to what has been observed in analogous studies of intramuscular injection of antipsychotics or lorazepam. Separation from placebo on the PANSS-EC was as early as 10 minutes postinhalation, the first time point where this was measured. Dysgeusia was the most commonly encountered spontaneously reported adverse event. Adverse events related to extrapyramidal symptoms and akathisia were relatively rare. Spirometry studies identified the potential for bronchospasm particularly in persons with asthma. Because of concerns over pulmonary safety, inhaled loxapine is restricted to use in hospitals and patients need to be prescreened for the presence of pulmonary disease, as well as monitored for signs and symptoms of

  10. Inhibitory effect of gold nanoparticles on the D-ribose glycation of bovine serum albumin

    Directory of Open Access Journals (Sweden)

    Liu W


    Full Text Available Weixi Liu,1 Menashi A Cohenford,1–3 Leslie Frost,3 Champika Seneviratne,4 Joel A Dain1 1Department of Chemistry, University of Rhode Island, Kingston, RI, USA; 2Department of Integrated Science and Technology, 3Department of Chemistry, Marshall University, Huntington, WV, USA; 4Department of Chemistry, College of the North Atlantic, Labrador, NL, Canada Abstract: Formation of advanced glycation end products (AGEs by nonenzymatic glycation of proteins is a major contributory factor to the pathophysiology of diabetic conditions including senile dementia and atherosclerosis. This study describes the inhibitory effect of gold nanoparticles (GNPs on the D-ribose glycation of bovine serum albumin (BSA. A combination of analytical methods including ultraviolet–visible spectrometry, high performance liquid chromatography, circular dichroism, and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF mass spectrometry were used to determine the extent of BSA glycation in the presence of citrate reduced spherical GNPs of various sizes and concentrations. GNPs of particle diameters ranging from 2 nm to 20 nm inhibited BSA’s AGE formation. The extent of inhibition correlated with the total surface area of the nanoparticles. GNPs of highest total surface area yielded the most inhibition whereas those with the lowest total surface area inhibited the formation of AGEs the least. Additionally, when GNPs’ total surface areas were set the same, their antiglycation activities were similar. This inhibitory effect of GNPs on BSA’s glycation by D-ribose suggests that colloidal particles may have a therapeutic application for the treatment of diabetes and conditions that promote hyperglycemia. Keywords: gold nanoparticles, glycation, AGEs, GNPs, BSA

  11. Micobacteriose em cães. Relato de casos em São Paulo - Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Larsson


    Full Text Available Na clínica dermatológica veterinária por vezes atendem-se carnívoros domésticos com lesões ulceradas de evolução prolongada e, geralmente, rebeldes à terapia usual, que podem ser originárias de infecções por micobactérias do gênero Mycobacterium. Pela escassez de descrições na bibliografia brasileira, pelo inusitado das lesões e pela resposta à terapia preconizada, descrevem-se dois casos de micobacteriose em caninos atendidos na FMVZ/USP. As cadelas (Pastor Alemão, Doberman, adultas, apresentavam lesões ulceradas graves, nas faces posteriores dos pavilhões auriculares, de aspecto granulomatoso, exsudativas, recobertas por crostas hemorrágicas. Inexistiam linfoadenomegalia satélite e tampouco sintomas nos demais sistemas orgânicos. Complementaram-se os exames físico, hematológico e radiológico por curetagem das lesões e biópsias de pele que foram então submetidas a exames histopatológico, bacteriológico (direto: técnicas de Holst-Mitchinson e Radhakrishna, Ziehl-Neelsen; cultivo (meios de Lowenstein-Jensen e de Stonebrink & Leslie, em diferentes temperaturas; teste de tuberculina (PPD mamífero e aviário. Demonstrou-se, na bacterioscopia e na histopatologia, a presença de bacilos ácido-álcool resistentes que não cresceram nos meios de cultivo convencionais, mesmo quando submetidos a várias temperaturas distintas, bem como quadro tecidual piogranulomatoso típico. Após a interposição da terapêutica tópica (solução de Burrow, sal sódico de rifamicina e parenteral (rifampicina obteve-se flagrante melhora com remissão do quadro lesional. Discutem-se a etiopatogenia do quadro e as condutas diagnóstica e terapêutica.

  12. Depression and frailty in later life: a systematic review

    Directory of Open Access Journals (Sweden)

    Vaughan L


    Full Text Available Leslie Vaughan,1 Akeesha L Corbin,1 Joseph S Goveas2 1Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC, USA; 2Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, MI, USA Abstract: Frailty and depression are important issues affecting older adults. Depressive syndrome may be difficult to clinically disambiguate from frailty in advanced old age. Current reviews on the topic include studies with wide methodological variation. This review examined the published literature on cross-sectional and longitudinal associations between frailty and depressive symptomatology with either syndrome as the outcome, moderators of this relationship, construct overlap, and related medical and behavioral interventions. Prevalence of both was reported. A systematic review of studies published from 2000 to 2015 was conducted in PubMed, the Cochrane Database of Systematic Reviews, and PsychInfo. Key search terms were “frailty”, “frail”, “frail elderly”, “depressive”, “depressive disorder”, and “depression”. Participants of included studies were ≥55 years old and community dwelling. Included studies used an explicit biological definition of frailty based on Fried et al’s criteria and a screening measure to identify depressive symptomatology. Fourteen studies met the inclusion/exclusion criteria. The prevalence of depressive symptomatology, frailty, or their co-occurrence was greater than 10% in older adults ≥55 years old, and these rates varied widely, but less in large epidemiological studies of incident frailty. The prospective relationship between depressive symptomatology and increased risk of incident frailty was robust, while the opposite relationship was less conclusive. The presence of comorbidities that interact with depressive symptomatology increased incident frailty risk. Measurement variability of depressive symptomatology and inclusion of older adults

  13. Assessing the effect of culturally specific audiovisual educational interventions on attaining self-management skills for chronic obstructive pulmonary disease in Mandarin- and Cantonese-speaking patients: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Poureslami I


    Full Text Available Iraj Poureslami,1,2 Susan Kwan,3 Stephen Lam,4,5 Nadia A Khan,6,7 John Mark FitzGerald 8,9 1Respiratory Division, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada; 2Department of Graduate Studies, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, Vancouver, Canada; 3Respiratory Department, Burnaby Hospital, University of British Columbia, Burnaby, Canada; 4Respiratory Division, University of British Columbia, Vancouver, Canada; 5Department of Integrative Oncology, BC Cancer Research Centre, Vancouver, Canada; 6Department of Internal Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada; 7Department of Internal Medicine, Providence Health Care Authority, Vancouver, Canada; 8VGH Divisions of Respiratory Medicine, University of British Columbia, Vancouver, Canada; 9Respiratory Medicine, Vancouver Coastal Health Authority, Vancouver Coastal Health Research Institute, Institute for Heart and Lung Health, The Lung Centre, Gordon and Leslie Diamond Health Care Centre, Vancouver, Canada Background: Patient education is a key component in the management of chronic obstructive pulmonary disease (COPD. Delivering effective education to ethnic groups with COPD is a challenge. The objective of this study was to develop and assess the effectiveness of culturally and linguistically specific audiovisual educational materials in supporting self-management practices in Mandarin- and Cantonese-speaking patients. Methods: Educational materials were developed using participatory approach (patients involved in the development and pilot test of educational materials, followed by a randomized controlled trial that assigned 91 patients to three intervention groups with audiovisual educational interventions and one control group (pamphlet. The patients were recruited from outpatient clinics. The primary outcomes were improved inhaler technique and

  14. Mechanistic study of the toxicity of ionizing radiation in Daphnia magna

    Energy Technology Data Exchange (ETDEWEB)

    Parisot, F.; Alonzo, F. [Institut de Radioprotection et de Surete Nucleaire, IRSN/PRP-ENV/SERIS/LECO, Laboratoire d' Ecotoxicologie des Radionucleides, Cadarache (France); Bourdineaud, J.P. [UMR CNRS 5805 EPOC - OASU Station Marine d' Arcachon Universite Bordeaux 1, Arcachon (France); Poggiale, J.C. [Mediterranean Institute of Oceanography - MIO - UMR 7294 Pytheas Institute - OSU, Aix-Marseille University, Marseille (France)


    radiation in Daphnia magna. DEBtox is a biology-based model describing how energy is taken from food and allocated to growth and reproduction and how chronic exposure to toxicants may lead to metabolic perturbations in this energy budget. Outcomes in terms of survival and reproduction will be combined into Leslie matrices to project consequences to the population level. Document available in abstract form only. (authors)

  15. Reviews of recent publications

    Directory of Open Access Journals (Sweden)


    Full Text Available Culture and Theory Conley, Verena Andermatt, ed. Rethinking Technologies by Laurence M. Porter Leitch, Vincent B. Cultural Criticism, Literary Theory, Poststructuralism by Merry M. Pawlowski French Studies Bersani, Leo and Ulysse Dutoit. Arts of Impoverishment: Beckett, Rothko, Resnais by Thomas Trezise Boldt-Irons, Leslie Anne. On Bataille: Critical Essays by Walter A. Strauss Deleuze, Gilles. Negotiations . Trans. Martin Joughin by Charles J. Stivale Fisher, Dominique D. Staging of Language and Language(s of the Stage: Mallarmé's poëme critique and Artaud's poetry-minus-text by Maryse Fauvel Goodall, Jane. Artaud and the Gnostic Drama by Claudine G. Fisher Lydon, Mary. Skirting the Issue: Essays in Literary Theory by Carol J. Murphy German Studies Barnouw, Dagmar. Critical Realism: History, Photography, and the Work of Siegfried Kracauer by Florence Martin Pfandl-Buchegger, Ingrid. David Lodge als Literaturkritiker, Theoretiker and Romanautor by Charles A. Grair Samuels, Clarise. Holocaust Visions: Surrealism and Existentialism in the Poetry of Paul Celan by Francis Michael Sharp Stefan, Verena. Shedding and Literally Dreaming. Shedding. Trans. Johanna Steigleder Moore and Beth E. Weckmueller; Literally Dreaming . Trans. Johanna Albert and Tobe Levin; "Euphoria and Cacophony." Trans. and Afterword Tobe Levin by Miriam Frank Stern, J.P. The Dear Purchase: A Theme in German Modernism by Theodore Ziolkowski Russian Studies Berry, Ellen E. and Anesa Miller-Pogacer, eds. Re-Entering the Sign: Articulating New Russian Culture by Rolf Hellebust Erlich, Victor. Modernism and Revolution: Russian Literature in Transition by Henry Elbaum Hohne, Karen and Helen Wussow, eds. A Dialogue of Voices: Feminist Literary Theory and Bakhtin by Laura Beraha Masing-Delic, Irene. Abolishing Death: A Salvation Myth of Russian Twentieth-Century Literature by Rolf Hellebust Paperno, Irina and Joan Delaney Grossman, eds. Creating Life: The Aesthetic Utopia of Russian

  16. Modeling demographic performance of northern spotted owls relative to forest habitat in Oregon (United States)

    Olson, Gail S.; Glenn, Elizabeth M.; Anthony, Robert G.; Forsman, Eric D.; Reid, Janice A.; Loschl, Peter J.; Ripple, William J.


    Northern spotted owls (Strix occidentalis caurina) are known to be associated with late-successional forests in the Pacific Northwest of the United States, but the effects of habitat on their demographic performance are relatively unknown. We developed statistical models relating owl survival and productivity to forest cover types within the Roseburg Study Area in the Oregon Coast Range of Oregon, USA. We further combined these demographic parameters using a Leslie-type matrix to obtain an estimate of habitat fitness potential for each owl territory (n = 94). We used mark–recapture methods to develop models for survival and linear mixed models for productivity. We measured forest composition and landscape patterns at 3 landscape scales centered on nest and activity sites within owl territories using an aerial photo-based map and a Geographic Information System (GIS). We also considered additional covariates such as age, sex, and presence of barred owls (Strix varia), and seasonal climate variables (temperature and precipitation) in our models. We used Akaike's Information Criterion (AIC) to rank and compare models. Survival had a quadratic relationship with the amount of late- and mid-seral forests within 1,500 m of nesting centers. Survival also was influenced by the amount of precipitation during the nesting season. Only 16% of the variability in survival was accounted for by our best model, but 85% of this was due to the habitat variable. Reproductive rates fluctuated biennially and were positively related to the amount of edge between late- and mid-seral forests and other habitat classes. Reproductive rates also were influenced by parent age, amount of precipitation during nesting season, and presence of barred owls. Our best model accounted for 84% of the variability in productivity, but only 3% of that was due to the habitat variable. Estimates of habitat fitness potential (which may range from 0 to infinity) for the 94 territories ranged from 0.74 to 1

  17. Jobs and Education: A Progress Report and Open Forum (United States)

    Nero, Anthony V.


    session). Diandra L. Leslie-Pelecky (University of Nebraska, Forum on Education newsletter editor) will report on the AAPT/APS Department Chairs Conference held in May on "physics graduate education for diverse career options." Leonard J. Brillson (Xerox Webster Research Center, Chair of the Forum on Industrial and Applied Physics) will discuss FIAP's plans for more effectively connected employers and physicists, as well as other jobs-related initiatives. James K. Freericks (Georgetown University, member of the steering committee for the planned Forum on Careers and Professional Development) will discuss plans of the new Forum.

  18. Smartphone-Enabled Health Coaching Intervention (iMOVE) to Promote Long-Term Maintenance of Physical Activity in Breast Cancer Survivors: Protocol for a Feasibility Pilot Randomized Controlled Trial. (United States)

    Ritvo, Paul; Obadia, Maya; Santa Mina, Daniel; Alibhai, Shabbir; Sabiston, Catherine; Oh, Paul; Campbell, Kristin; McCready, David; Auger, Leslie; Jones, Jennifer Michelle


    measured peak oxygen consumption. Secondary clinical outcomes include health-related quality of life and anthropometric measures. All outcome measures are administered at baseline, after exercise program (month 3), and 6 months after program (month 9). This pilot RCT will inform full-scale RCT planning. We will assess pilot procedures and interventions and collect preliminary effect estimates. NCT02620735; (Archived by WebCite at ©Paul Ritvo, Maya Obadia, Daniel Santa Mina, Shabbir Alibhai, Catherine Sabiston, Paul Oh, Kristin Campbell, David McCready, Leslie Auger, Jennifer Michelle Jones. Originally published in JMIR Research Protocols (, 24.08.2017.

  19. Influence of Information and Communication Technologies on the Resilience and Coping of Sexual and Gender Minority Youth in the United States and Canada (Project #Queery): Mixed Methods Survey. (United States)

    Craig, Shelley L; McInroy, Lauren B; D'Souza, Sandra A; Austin, Ashley; McCready, Lance T; Eaton, Andrew D; Shade, Leslie R; Wagaman, M Alex


    data, (2) grounded theory analysis of qualitative data, and (3) an integrative, mixed methods analysis using a data transformation design. Theoretical and methodological triangulation of analyses integrates an interwoven pattern of results into a comprehensive picture of a phenomenon. Results will be reported in 2017 and 2018. This research study will provide critical insights into the emerging use of ICTs by sexual and gender minority youth and identify intervention strategies to improve their well-being and reduce risks encountered by this vulnerable population. Implications for practice, research, and knowledge translation are provided. ©Shelley L Craig, Lauren B McInroy, Sandra A D'Souza, Ashley Austin, Lance T McCready, Andrew D Eaton, Leslie R Shade, M Alex Wagaman. Originally published in JMIR Research Protocols (, 28.09.2017.

  20. A mechanistic approach to link biological effects of radioactive substances from molecules to populations in wildlife species - A mechanistic approach to link biological effects of radionuclides from molecules to populations in wildlife species

    Energy Technology Data Exchange (ETDEWEB)

    Alonzo, Frederic; Parisot, Florian; Plaire, Delphine; Adam-Guillermin, Christelle; Garnier- Laplace, Jacqueline [Institut de Radioprotection et de Surete Nucleaire (IRSN), PRP-ENV, SERIS, LECO, Cadarache, Saint-Paul- Lez-Durance, 13115 (France)


    of action was confirmed by measurements of assimilation reduction and observations of histological alteration of the digestive epithelium. However the mechanisms involved in the trans-generational increase in sensitivity remained unknown. A recent study investigated DNA damage in daphnids exposed to uranium, demonstrating that molecular alterations were accumulated in females over the course of exposure and transmitted to their progeny. Such alterations were interpreted as the underlying mechanism causing the increase in effect severity over generations and are now investigated during exposures to Cs-137 and, as a future perspective, to Am-241. A DEBtox model considering the accumulation and transmission of genetic damage was used to analyse radionuclides effects on life history in daphnids exposed over successive generations. Modelling outcomes were projected to the population level using Leslie matrices, in order to explore ecological consequences of exposure to radionuclides at a relevant scale for biota protection. (authors)

  1. Lack of tolerable treatment options for patients with schizophrenia

    Directory of Open Access Journals (Sweden)

    Citrome L


    Full Text Available Leslie Citrome,1 Anna Eramo,2 Clement Francois,2 Ruth Duffy,3 Susan N Legacy,3 Steve J Offord,3 Holly B Krasa,3 Stephen S Johnston,4 Alice Guiraud-Diawara,5 Siddhesh A Kamat,3 Patricia Rohman3 1Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, NY, 2Lundbeck, Deerfield, IL, 3Otsuka America Pharmaceuticals, Princeton, NJ, 4Truven Health Analytics, Bethesda, MD, USA; 5Lundbeck SAS, Issy-les-Moulineaux, France Purpose: Atypical antipsychotics (AAs, an effective treatment for schizophrenia, have a range of pharmacologic properties leading to differences in tolerability as well as heterogeneity in treatment response. Individual patient characteristics must be considered when making treatment choices, especially from an adverse event (AE or tolerability perspective. Despite the availability of numerous AAs, after appraising patient characteristics at the time of treatment selection, physicians may quickly run out of tolerable treatment options. Patients and methods: AE risk factors, defined as having either a prior history of an AE or a risk factor for that AE, were determined for Medicaid-insured and Commercially insured patients using database analysis. Patients receiving AA treatment between January 1, 2010 and December 31, 2012 defined the index date of first observed AA prescription during this period. Nine AAs were evaluated for association with AE risk factors as informed by drug prescribing information from the different manufacturers and published meta-analyses. The proportion of patients with pre-index AE risk factors prescribed an AA associated with that risk factor was then determined. Results: A high proportion of patients (>80% were prescribed an AA associated with extrapyramidal symptoms or akathisia despite experiencing extrapyramidal symptoms or akathisia prior to AA treatment initiation. Similar trends were observed among patients with diabetes (>60% and obesity (>40%. From the nine treatment

  2. Command and Control of Space Assets Through Internet-Based Technologies Demonstrated (United States)

    Foltz, David A.


    The NASA Glenn Research Center successfully demonstrated a transmission-control-protocol/ Internet-protocol- (TCP/IP) based approach to the command and control of onorbit assets over a secure network. This is a significant accomplishment because future NASA missions will benefit by using Internet-standards-based protocols. Benefits of this Internet-based space command and control system architecture include reduced mission costs and increased mission efficiency. The demonstration proved that this communications architecture is viable for future NASA missions. This demonstration was a significant feat involving multiple NASA organizations and industry. Phillip Paulsen, from Glenn's Project Development and Integration Office, served as the overall project lead, and David Foltz, from Glenn's Satellite Networks and Architectures Branch, provided the hybrid networking support for the required Internet connections. The goal was to build a network that would emulate a connection between a space experiment on the International Space Station and a researcher accessing the experiment from anywhere on the Internet, as shown. The experiment was interfaced to a wireless 802.11 network inside the demonstration area. The wireless link provided connectivity to the Tracking and Data Relay Satellite System (TDRSS) Internet Link Terminal (TILT) satellite uplink terminal located 300 ft away in a parking lot on top of a panel van. TILT provided a crucial link in this demonstration. Leslie Ambrose, NASA Goddard Space Flight Center, provided the TILT/TDRSS support. The TILT unit transmitted the signal to TDRS 6 and was received at the White Sands Second TDRSS Ground Station. This station provided the gateway to the Internet. Coordination also took place at the White Sands station to install a Veridian Firewall and automated security incident measurement (ASIM) system to the Second TDRSS Ground Station Internet gateway. The firewall provides a trusted network for the simulated space

  3. Spiritual care may impact mental health and medication adherence in HIV+ populations

    Directory of Open Access Journals (Sweden)

    Oji VU


    Full Text Available Valerie U Oji,1–3 Leslie C Hung,3 Reza Abbasgholizadeh,1,4 Flora Terrell Hamilton,5 E James Essien,6 Evaristus Nwulia7 1Lifefountain Center Ministries Inc, Houston, TX, USA; 2Feik School of Pharmacy, University of the Incarnate Word, San Antonio, TX, USA; 3University of Texas, College of Pharmacy, Austin, TX, USA; 4University of Houston, Houston, TX, USA; 5Administration, Family & Medical Counseling Service, Inc. (FMCS, Washington, DC, USA; 6University of Houston Institute for Community Health, Houston, TX, USA; 7Psychiatry, Howard University Translational Neuroscience Laboratory, Washington, DC, USA Objective: To explore a potential role for spirituality in medication-related needs assessment for integrated care in chronically ill populations. Method: A systematic literature review was conducted to explore the impact of faith beliefs on health and/or medication adherence in individuals with depression and/or HIV+/AIDS. Retrospective electronic medical record review of adult HIV+ patients of an urban primary care clinic with integrated mental health services was conducted, with Substance Abuse and Mental Illness Symptoms Screener (SAMISS, major depressive disorder (MDD incidence over the preceding year, and history of contact with a spiritual advisor. A convenience sample was interviewed to qualitatively assess potential medication therapy management needs and medication-related problems. Another sample was examined utilizing the Daily Spiritual Experience Scale. Results: The literature reports positive influence on health behaviors, coping and outcomes; and poor medication adherence and treatment decisions due to patient passivity or resistance. Spiritual advisor contact (not limited to a specific religion was significantly associated with MDD absence (1.7% vs. 15.3%, P<0.005 and inversely related to SAMISS, depression, and poor health behaviors. Patient interviews reflected significance of faith in terms of insight and acceptance of

  4. Sollicitude, dépendance et lien social

    Directory of Open Access Journals (Sweden)

    Monique Lanoix


    Full Text Available La croissance de la population vieillissante en Amérique du Nord a un impact significatif sur nos politiques sociales. Ainsi, l’État québécois met à la disposition des personnes âgées une aide afin de faciliter le maintien à domicile. Qui a maintenant la responsabilité de répondre aux besoins des personnes âgées; est-ce la famille ou l’État? Si la réponse peut nous aider à formuler des politiques sociales équitables, elle nous pousse aussi à repenser le lien social à la lumière de la dépendance. Dans un premier temps nous nous pencherons sur l’évolution de l’éthique de la sollicitude pour ensuite analyser les apports des études sur la production du handicap. Puisque la problématique de la dépendance s’avère cruciale dans ce débat, les écrits de deux théoriciens français, Albert Memmi et Bernard Ennuyer, nous aideront à élucider la question de la dépendance. Nous verrons par la suite comment ces divers apports peuvent nous amener à reconceptualiser le lien social.In this paper I examine whether care ethics can help to conceptualize a richer social ontology which would include a variety of individuals, not only productive ones, under the auspices of justice. In the first part of the paper, I consider the reasons why care ethics has not had a profound impact in political theorizing. Next I examine the troubled relationship of care ethics and disability. Recent writings on social contract theory, in particular those of Anita Silvers and Leslie Pickering as well as Lawrence Becker, argue that social contract theory can include profoundly disabled individuals and I contrast their proposals with that of care ethicists. By examining critical writings on dependency, I show that a strategy for a more inclusive social space needs to include social structures that recognize dependency as a human reality. I argue that care ethics, even if it may not be critical enough of the foundational concept of dependence, is

  5. Lapatinib in patients with metastatic breast cancer following initial treatment with trastuzumab: an economic analysis from the Brazilian public health care perspective

    Directory of Open Access Journals (Sweden)

    Machado M


    Full Text Available Marcio Machado,1 Thomas R Einarson21GlaxoSmithKline Brasil Ltd, Rio de Janeiro, Brazil; 2Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, CanadaObjective: To evaluate, from the perspective of the Brazilian public health care system, the cost-effectiveness of lapatinib plus capecitabine (LAP/CAP versus capecitabine alone (CAP or trastuzumab plus capecitabine (TRAST/CAP in the treatment of women with human epidermal growth factor receptor-2-positive metastatic breast cancer previously treated with trastuzumab.Methods: An economic model was developed to compare costs and clinical outcomes over a 5-year time horizon. Both costs and outcomes were discounted at a 5% rate, in accordance with Brazilian pharmacoeconomic guidelines. Clinical inputs were determined using indirect treatment comparisons. Costs were derived from public reimbursement databases and reported in 2010 Brazilian real (R$1 = USD$0.52. Clinical outcomes included progression-free survival years (PFYs, life-years (LYs and quality-adjusted life-years (QALYs. The economic outcome was the incremental cost per LY, PFY, or QALY gained. The impact of variations in individual inputs (eg, drug cost, drug effectiveness was examined using one-way sensitivity analyses. Overall model robustness was tested using probabilistic sensitivity analyses, varying the ranges of all input parameters within their standard distributions.Results: Expected cost per patient was R$41,195 for CAP, R$95,256 for LAP/CAP, and R$113,686 for TRAST/CAP. Respective LYs were 1.406, 1.695, and 1.465; PFYs were 0.473, 0.711, and 0.612; and QALYS were 0.769, 0.958, and 0.827. LAP/CAP dominated TRAST/CAP for all outcomes. Incremental cost-effectiveness ratios of LAP/CAP over CAP were R$186,563 for LYs, R$226,403 for PFYs, and R$284,864 for QALYs. Results remained unchanged in one-way sensitivity analyses. In probabilistic analyses, LAP/CAP was dominant over TRAST/CAP in 93.5% of simulations.Conclusion: LAP

  6. Decline in Mycobacterium bovis and Brucella abortus populations during the maturation of experimentally contaminated parmesan-type cheese

    Directory of Open Access Journals (Sweden)

    Karina Ramirez Starikoff


    Full Text Available Brazilian legislation allows the manufacture of raw milk cheese with a maturation exceeding 60 days at room temperature above 5°C, but there is a lack of solid scientific evidence on the efficacy of this maturation process in inactivating important pathogens that may be present in milk, such as Mycobacterium bovis and Brucella abortus. Thus, the objectives of this study were to produce parmesan-type cheese experimentally contaminated with M. bovis and B. abortus and evaluate the survival of these pathogens along 2-month maturation. Parmesan-type cheese was manufactured in the laboratory using whole pasteurized milk with or without inoculation with M. bovis (SB1033 or B. abortus (1119-3 and matured at 18°C for up to 63 days. M. bovis was inoculated in Stonebrink-Leslie medium supplemented with antibiotics and incubated at 37°C for 45 days, and B. abortus was incubated in Farrel medium at 36°C for 3 days. The average D18°C value, weighted by variance, was 37.5 ± 5.3 days for M. bovis and 5.9 ± 0.7 days for B. abortus. The average physicochemical parameters in the cheese at the end of the study were as follows: pH = 4.89, water activity = 0.976, and moisture percentage = 43.1%. The pH might have contributed to the reduction in the population of B. abortus but seems not to have influenced the population of M. bovis. We conclude that the duration of the maturation process influences the size of the surviving populations of M. bovis and B. abortus, and that the shortening of the maturation duration might not ensure a decline in pathogen levels to safe levels. Thus, complementary studies considering the effect of several other technological aspects on the survival of these pathogens are required, including the effect of the lactic acid bacterial population, salt content, and temperature of maturation.

  7. Incentivizing health care behaviors in emerging adults: a systematic review

    Directory of Open Access Journals (Sweden)

    Yu CH


    Full Text Available Catherine H Yu,1,2 Giuliana Guarna,1 Pamela Tsao,3 Jude R Jesuthasan,1 Adrian NC Lau,3,4 Ferhan S Siddiqi,1 Julie Anne Gilmour,3 Danyal Ladha,1 Henry Halapy,5 Andrew Advani1–3 1Li Ka Shing Knowledge Institute, St Michael’s Hospital, 2Division of Endocrinology and Metabolism, Department of Medicine, St Michael’s Hospital, University of Toronto, 3Department of Medicine, Faculty of Medicine, University of Toronto, 4Division of Endocrinology, Department of Medicine, University Health Network, 5Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada Purpose: For emerging adults with chronic medical diseases, the transition from pediatric to adult health care is often a time of great upheaval, commonly associated with unhealthy self-management choices, loss to follow-up, and adverse outcomes. We conducted a systematic review to examine the use of incentive strategies to promote positive health-related behaviors in young adults with chronic medical diseases.Methods: The Medline, CINAHL, Embase, PsycInfo, and Cochrane databases were searched through June 2014. Studies of any design where an incentive was used to achieve a target behavior or outcome in a pediatric or emerging adult population (age <30 years with chronic medical conditions including addictions, were included.Results: A total of 26 studies comprising 10,880 patients met our inclusion criteria after screening 10,305 abstracts and 301 full-text articles. Of these studies, 20 examined the effects of behavioral incentives on cigarette smoking or substance abuse, including alcohol; four studies explored behavioral incentives in the setting of HIV or sexual health; and two articles studied individuals with other chronic medical conditions. Seventeen articles reported a statistically significant benefit of the behavioral incentive on one or more outcomes, although only half reported follow-up after the incentive period was terminated.Conclusion: While the majority of

  8. The role of the pharmacist in patient-centered medical home practices: current perspectives

    Directory of Open Access Journals (Sweden)

    Lewis NJW


    Full Text Available Nancy JW Lewis,1 Leslie A Shimp,2 Stuart Rockafellow,2 Jeffrey M Tingen,2 Hae Mi Choe,3 Marie A Marcelino21Private consultancy practice, Rochester Hills, MI, USA; 2Clinical, Social and Administrative Department, University of Michigan College of Pharmacy, Ann Arbor, MI, USA; 3Department of Pharmacy Services, University of Michigan Health System, Ann Arbor, MI, USAAbstract: Patient-centered medical homes (PCMHs are the centerpiece of primary care transformation in the US. They are intended to improve care coordination and communication, enhance health care quality and patient experiences, and lower health care costs by linking patients to a physician-led interdisciplinary health care team. PCMHs are widely supported by health care associations, payers, and employers. Health care accreditation organizations have created performance measures that promote the adoption of PCMH core attributes. Public and private payers are increasingly providing incentives and bonuses related to performance measure status. Evidence-based prescription, medication adherence, medication use coordination, and systems to support medication safety are all necessary components of PCMHs. Pharmacists have unique knowledge and skills that can complement the care provided by other PCMH team members. Their experience in drug therapy assessments, medication therapy management, and population health has documented benefits, both in terms of patient health outcomes and health care costs. Through collaborative care, pharmacists can assist physicians and other prescribers in medication management and thus improve prescriber productivity and patient access to care. Pharmacists are engaged in PCMHs through both employment and contractual arrangements. While some pharmacists serve a unique PCMH, others work within practice networks that serve practices within a geographical area. Financial support for pharmacist-provided services includes university funding, external grant funding

  9. The effect of humidity and temperature on visual outcomes after myopic corneal laser refractive surgery

    Directory of Open Access Journals (Sweden)

    Hood CT


    Full Text Available Christopher T Hood,1 Roni M Shtein,1 Daniel Veldheer,1,2 Munira Hussain,1 Leslie M Niziol,1 David C Musch,1,3 Shahzad I Mian1 1Department of Ophthalmology and Visual Sciences, University of Michigan W.K. Kellogg Eye Center, Ann Arbor, MI, 2Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, 3Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA Objective: To determine whether procedure room environmental conditions are associated with outcomes after myopic laser in situ keratomileusis (LASIK or laser-assisted keratomileusis (LASEK. Design: Retrospective chart review. Participants: Eight hundred sixty-three eyes of 458 consecutive patients at a university-based academic practice. Methods: We reviewed the medical records of consecutive patients who underwent LASIK or LASEK over a 3-year period. Linear mixed regression models were used to investigate the association of laser room temperature and humidity with the outcomes of visual acuity and postoperative manifest spherical equivalent refraction. Repeated measures logistic regression models were used for the outcomes of diffuse lamellar keratitis (DLK and need for enhancement surgery. Results: Subjects were on an average 38.6 years old at the time of surgery (standard deviation [SD] =10.3 and the average spherical equivalent refraction of eyes was 3.8 diopters (SD =2.03. Regression models did not reveal a significant association between temperature and uncorrected distance visual acuity (UDVA or corrected distance visual acuity (CDVA, or between humidity and UDVA (P>0.05 for all. However, increased humidity was associated with a small but statistically significant improvement in CDVA after LASIK at 1 day, 1 month, 3 months, and 1 year postoperatively (P<0.05 for all. There was no significant association between temperature and humidity and the need for enhancement, the incidence of DLK, or postoperative manifest refraction. Conclusion: While increased laser

  10. Cholesterol testing among men and women with disability: the role of morbidity

    Directory of Open Access Journals (Sweden)

    Lofters AK


    Full Text Available Aisha K Lofters,1–3,* Sara JT Guilcher,1,3,4,* Lauren Webster,1 Richard H Glazier,1–3 Susan B Jaglal,1 Ahmed M Bayoumi,1,3 1Institute for Clinical Evaluative Sciences, 2Department of Family and Community Medicine, St Michael’s Hospital, University of Toronto, 3Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St Michael’s Hospital, 4Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada *These authors contributed equally to this work Purpose: Despite more frequent use of health services by people living with disability, the quality of preventive care received may be suboptimal. In this retrospective cohort study, we used administrative data to examine the relationship between cholesterol testing and levels of disability and morbidity among women and men in Ontario, Canada. Methods: We linked multiple provincial-level databases in this study. In stratified analyses for women and men, we used multivariable logistic regression to examine differences in cholesterol testing, and we tested for an interaction effect between disability and morbidity. In a secondary analysis, we tested for a three-way interaction between sex, disability, and morbidity on the entire cohort. Results: There was an interaction between morbidity and disability for both women and men. Women and men with no chronic conditions appeared to be least likely to be up-to-date on cholesterol testing, and among this group, those with moderate disability were more likely to be up-to-date on cholesterol testing than those with no disability (adjusted odds ratio [AOR] =1.51; 95% confidence interval [CI] 1.20–1.90 for women; AOR =1.16; 95% CI 1.00–1.34 for men. Among women and men who had one chronic condition, having severe disability put them at significant disadvantage versus those with no disability. Only 58.5% of men with no disability and no chronic conditions were up-to-date on cholesterol testing. Conclusion: An intermediate level

  11. Learner Outcomes in Science in South Africa: Role of the Nature of Learner Difficulties with the Language for Learning and Teaching Science (United States)

    Oyoo, Samuel Ouma


    Paul Leslie Gardner pioneered the study of student difficulties with everyday words presented in the science context (Gardner 1971); several similarly designed studies (e.g. Cassels and Johnstone 1985; Tao in Research in Science Education, 24, 322-330, 1994; Farell and Ventura in Language and Education, 12(4), 243-254, 1998; Childs and O'Farell in Chemistry Education: Research and Practice, 4(3), 233-247, 2003) have since been reported in literature. This article draws from an exploratory study of the difficulties South African High School physical science learners encounter with everyday English words when presented in the science context. The participants (1107 learners and 35 respective physical science teachers) were drawn from 35 public secondary schools in Johannesburg area of South Africa. Data were obtained through a word test to participant learners followed by group interviews but face-to-face interviews with each physical science teacher. This study has revealed that in similar ways as have been reported in each of the studies so far, South African learners also face difficulties with meanings of everyday words presented in a science context. The main source of difficulties encountered was learner inability to distinguish between the meanings of familiar everyday words as used in everyday parlance from the `new' meanings of the same everyday words when used in the science context. Interpretations of learner interview responses revealed that fewer difficulties would have been experienced by learners if science teachers generally explained the context meanings of the words as used during science teaching. The findings suggest that focusing on contextual proficiency more than on general proficiency in the language of learning and teaching (LOLT) during teaching perhaps holds more promise for enhanced learning and achievement in science. Steps necessary to raise teacher awareness of the potential impact of context on meanings of everyday words of the LOLT

  12. Multi-Scale Aspects of Tropical Cyclone Predictability (United States)

    Doyle, J. D.; Moskaitis, J.; Black, P. G.; Hendricks, E. A.; Reinecke, A.; Amerault, C. M.


    discussed for other cases from the HS3 and TCI programs, including Nadine , Leslie (2012), and Gabrielle (2013), as well as other storms such as Superstorm Sandy (2012).

  13. Effects of asenapine on agitation and hostility in adults with acute manic or mixed episodes associated with bipolar I disorder

    Directory of Open Access Journals (Sweden)

    Citrome L


    Full Text Available Leslie Citrome,1 Ronald Landbloom,2 Cheng-Tao Chang,3 Willie Earley4 1Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, NY, USA; 2Department of Neuroscience, Merck, Whitehouse Station, NJ, USA; 3Biostatistics, Allergan, Jersey City, NJ, USA; 4Clinical Development, Allergan, Jersey City, NJ, USA Background: Bipolar disorder is associated with an increased risk of aggression. However, effective management of hostility and/or agitation symptoms may prevent patients from becoming violent. This analysis investigated the efficacy of the antipsychotic asenapine on hostility and agitation in patients with bipolar I disorder.Methods: Data were pooled from three randomized, double-blind, placebo-controlled, Phase III trials of asenapine in adults with manic or mixed episodes of bipolar I disorder (NCT00159744, NCT00159796, and NCT00764478. Post hoc analyses assessed the changes from baseline to day 21 on the Young Mania Rating Scale (YMRS and the Positive and Negative Syndrome Scale (PANSS hostility-related item scores in asenapine- or placebo-treated patients with at least minimal or mild symptom severity and on the PANSS-excited component (PANSS-EC total score in agitated patients. Changes were adjusted for improvements in overall mania symptoms to investigate direct effects on hostility.Results: Significantly greater changes in favor of asenapine versus placebo were observed in YMRS hostility-related item scores (irritability: least squares mean difference [95% confidence interval] =–0.5 [–0.87, –0.22], P=0.001; disruptive–aggressive behavior: –0.7 [–0.99, –0.37], P<0.0001, PANSS hostility item score (–0.2 [–0.44, –0.04]; P=0.0181, and PANSS-EC total score (–1.4 [–2.4, –0.4]; P=0.0055. Changes in the YMRS disruptive–aggressive behavior score and the sum of the hostility-related items remained significant after adjusting for improvements in other YMRS item scores.Conclusion: Asenapine

  14. Characteristics of binge eating disorder in relation to diagnostic criteria

    Directory of Open Access Journals (Sweden)

    Wilfley DE


    Full Text Available Denise E Wilfley,1 Leslie Citrome,2 Barry K Herman3 1Department of Psychiatry, Washington University School of Medicine, St Louis, MO, 2Department of Psychiatry & Behavioral Sciences, New York Medical College, Valhalla, NY, 3Global Medical Affairs, Shire, Lexington, MA, USA Abstract: The objective of this review was to examine the evidentiary basis for binge eating disorder (BED with reference to the Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (DSM-5 diagnostic criteria for BED. A PubMed search restricted to titles and abstracts of English-language reviews, meta-analyses, clinical trials, randomized controlled trials, journal articles, and letters using human participants was conducted on August 7, 2015, using keywords that included “binge eating disorder,” DSM-5, DSM-IV, guilt, shame, embarrassment, quantity, psychological, behavior, and “shape and weight concerns.” Of the 257 retrieved publications, 60 publications were considered relevant to discussions related to DSM-5 diagnostic criteria and were included in the current review, and 20 additional references were also included on the basis of the authors’ knowledge and/or on a review of the reference lists from relevant articles obtained through the literature search. Evidence supports the duration/frequency criterion for BED and the primary importance of loss of control and marked distress in identifying individuals with BED. Although overvaluation of shape/weight is not a diagnostic criterion, its relationship to the severity of BED psychopathology may identify a unique subset of individuals with BED. Additionally, individuals with BED often exhibit a clinical profile consisting of psychiatric (eg, mood, obsessive–compulsive, and impulsive disorders and medical (eg, gastrointestinal symptoms, metabolic syndrome, and type 2 diabetes comorbidities and behavioral profiles (eg, overconsumption of calories outside of a binge eating episode and emotional

  15. Evaluating adherence to ocular hypotensives using the Travatan dosing aid

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    O'Dell L


    Full Text Available Leslie O'Dell1, Amy L Hennessy2,3, Alan L Robin2–41May Eye Care Center, Hanover, PA, USA; 2Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; 3Glaucoma Specialists, Baltimore, MD, USA; 4Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USAPurpose: The Travatan™ Dosing Aid (TDA is the first commercially available device designed to aid in patients' adherence to their glaucoma therapies and to record patients' eyedrop administration, so that doctors can better assess adherence. No prior studies have objectively evaluated adherence to glaucoma medications and its relationship to the severity of glaucoma or the use of multiple systemic medications.Methods: We enrolled 100 consecutive subjects from a private glaucoma practice, all currently using topical travoprost 0.004%. Each subject was issued a TDA to record the time and date of each drop instilled. Informed consents were signed and the subjects were aware that their medication use was being monitored. Patients returned for follow-up 30–60 days after their initial exam.Results: 89 subjects completed the study: 44 were male, with a mean age of 67 years, and 69.7% were Caucasian. Overall, patient adherence was 74.8% (range 22%–100% improving to 85.4% on the day prior to follow-up. The mean number of missed doses per month was 6.24 ± 5.9. Only 7.9% of the study population never missed a dose and 23.6% ± 4.3% missed more than ten drops per month. No marked association was observed between the severity of glaucoma, race, or the number of systemic medications and adherence. A marked improvement in adherence was noted in patients using travoprost 0.004% as monocular therapy rather than binocular therapy, 84.0% ± 17.1% vs 67.4% ± 23.5% (P < 0.005.Conclusion: Patient adherence to glaucoma medical therapy is a major barrier in the management and treatment of glaucoma patients given the chronic nature and asymptomatic course of the disease. Until recently

  16. Mobile Phone Ownership Is Not a Serious Barrier to Participation in Studies: Descriptive Study. (United States)

    Harvey, Emily J; Rubin, Leslie F; Smiley, Sabrina L; Zhou, Yitong; Elmasry, Hoda; Pearson, Jennifer L


    requiring participants to use their personal mobile phones for data collection was not a major barrier to study participation for most respondents who completed the online screener, including those who were unemployed. NCT02261363; (Archived by WebCite at ©Emily J Harvey, Leslie F Rubin, Sabrina L Smiley, Yitong Zhou, Hoda Elmasry, Jennifer L Pearson. Originally published in JMIR Mhealth and Uhealth (, 19.02.2018.

  17. The patient perspective: arthritis care provided by Advanced Clinician Practitioner in Arthritis Care program-trained clinicians

    Directory of Open Access Journals (Sweden)

    Warmington K


    Full Text Available Kelly Warmington,1 Carol A Kennedy,2 Katie Lundon,3 Leslie J Soever,4 Sydney C Brooks,5 Laura A Passalent,6 Rachel Shupak,7 Rayfel Schneider,8 1Learning Institute, Hospital for Sick Children, 2Musculoskeletal Health and Outcomes Research, St Michael’s Hospital, 3Continuing Professional Development, Faculty of Medicine, University of Toronto, 4University Health Network, 5Ontario Division, Arthritis Society, 6Toronto Western Hospital, 7Division of Rheumatology, St Michael's Hospital, 8Division of Rheumatology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada Objective: To assess patient satisfaction with the arthritis care services provided by graduates of the Advanced Clinician Practitioner in Arthritis Care (ACPAC program. Materials and methods: This was a cross-sectional evaluation using a self-report questionnaire for data collection. Participants completed the Patient–Doctor Interaction Scale, modified to capture patient–practitioner interactions. Participants completed selected items from the Group Health Association of America's Consumer Satisfaction Survey, and items capturing quality of care, appropriateness of wait times, and a comparison of extended-role practitioner (ERP services with previously received arthritis care. Results: A total of 325 patients seen by 27 ERPs from 15 institutions completed the questionnaire. Respondents were primarily adults (85%, female (72%, and living in urban areas (79%. The mean age of participants was 54 years (range 3–92 years, and 51% were not working. Patients with inflammatory (51% and noninflammatory conditions (31% were represented. Mean (standard deviation Patient–Practitioner Interaction Scale subscale scores ranged from 4.50 (0.60 to 4.63 (0.48 (1 to 5 [greater satisfaction]. Overall satisfaction with the quality of care was high (4.39 [0.77], as was satisfaction with wait times (referral to appointment, 4.27 [0.86]; in clinic, 4.24 [0.91]. Ninety-eight percent of

  18. Clinical response and hospital costs associated with the empirical use of vancomycin and linezolid for hospital-acquired pneumonia in a Chinese tertiary care hospital: a retrospective cohort study

    Directory of Open Access Journals (Sweden)

    Song Y


    Full Text Available Yuanlin Song,1,* Yicheng Yang,2,* Wendong Chen,3,4 Wei Liu,2 Kai Wang,2 Xuehai Li,5 Ke Wang,2 Manny Papadimitropoulos,3,6 William Montgomery7 1Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 2Lilly Suzhou Pharmaceutical Co, Ltd, Shanghai Branch, Shanghai, People's Republic of China; 3Division of Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, 4Normin Health, Toronto, ON, Canada; 5VitalStrategic Research Institute, Shanghai, People's Republic of China; 6Global Health Outcomes Research, Eli Lilly, Indianapolis, IN, USA; 7Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia *These authors contributed equally to this work Aims: To evaluate clinical outcomes and allocation of hospital costs associated with empirical use of vancomycin or linezolid for hospital-acquired pneumonia (HAP in the People's Republic of China. Methods: Hospital episodes including HAP treated by vancomycin or linezolid between 2008 and 2012 in a Chinese tertiary care hospital were retrospectively identified from hospital administrative databases. Propensity score methods created best-matched pairs for the antibiotics. The matched pairs were used for adjusted comparisons on clinical response and allocation of hospital costs. Multiple regression analyses adjusting residual imbalance after matching were performed to confirm adjusted comparisons. Results: Sixty matched pairs were created. Adjusted comparisons between vancomycin and linezolid showed similar clinical response rates (clinical cure: 30.0% versus 31.7%, respectively; P=0.847; treatment failure: 55.0% versus 45.0%, respectively; P=0.289 but a significantly lower in-hospital mortality rate for vancomycin (3.3% versus 18.3%, respectively; P=0.013. After further adjusting for the imbalanced variables between matched treatment groups, the risks of treatment failure associated with the two antibiotics were comparable (odds ratio: 1.139; P=0.308 and there was

  19. Large Scale Water Vapor Sources Relative to the October 2000 Piedmont Flood (United States)

    Turato, Barbara; Reale, Oreste; Siccardi, Franco


    Very intense mesoscale or synoptic-scale rainfall events can occasionally be observed in the Mediterranean region without any deep cyclone developing over the areas affected by precipitation. In these perplexing cases the synoptic situation can superficially look similar to cases in which very little precipitation occurs. These situations could possibly baffle the operational weather forecasters. In this article, the major precipitation event that affected Piedmont (Italy) between 13 and 16 October 2000 is investigated. This is one of the cases in which no intense cyclone was observed within the Mediterranean region at any time, only a moderate system was present, and yet exceptional rainfall and flooding occurred. The emphasis of this study is on the moisture origin and transport. Moisture and energy balances are computed on different space- and time-scales, revealing that precipitation exceeds evaporation over an area inclusive of Piedmont and the northwestern Mediterranean region, on a time-scale encompassing the event and about two weeks preceding it. This is suggestive of an important moisture contribution originating from outside the region. A synoptic and dynamic analysis is then performed to outline the potential mechanisms that could have contributed to the large-scale moisture transport. The central part of the work uses a quasi-isentropic water-vapor back trajectory technique. The moisture sources obtained by this technique are compared with the results of the balances and with the synoptic situation, to unveil possible dynamic mechanisms and physical processes involved. It is found that moisture sources on a variety of atmospheric scales contribute to this event. First, an important contribution is caused by the extratropical remnants of former tropical storm Leslie. The large-scale environment related to this system allows a significant amount of moisture to be carried towards Europe. This happens on a time- scale of about 5-15 days preceding the

  20. Vascular quality of care pilot study: how admission to a vascular surgery service affects evidence-based pharmacologic risk factor modification in patients with lower extremity peripheral arterial disease

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    Steenhof N


    Full Text Available Naomi Steenhof,1,2 Francesca Le Piane,1 Kori Leblanc,1–3 Naomi R Eisenberg,4 Yvonne Kwan,1 Christine Malmberg,1,6 Alexandra Papadopoulos,5,7 Graham Roche-Nagle4,7,8 1Department of Pharmacy, University Health Network, 2Leslie Dan Faculty of Pharmacy, University of Toronto, 3Centre for Innovation in Complex Care, University Health Network, 4Division of Vascular Surgery, University Health Network, 5Faculty of Nursing, University of Toronto, Toronto, ON, 6Victoria General Hospital, Vancouver Island Health Authority, Victoria, BC, 7Peter Munk Cardiac Centre, University Health Network, 8Faculty of Medicine, University of Toronto, Toronto, ON, Canada Background: Peripheral arterial disease (PAD guidelines recommend aggressive risk factor modification to improve cardiovascular outcomes. Recommended pharmacologic therapies include antiplatelets, angiotensin converting enzyme (ACE inhibitors, and HMG-CoA-reductase inhibitors (statins. Purpose: We studied the degree to which patient admission to a vascular surgery service increased the use of these therapies. Patients and methods: The authors conducted a retrospective chart review of 150 patients with PAD admitted to the vascular surgery service at a large Canadian tertiary care hospital. The use of recommended pharmacologic therapies at the time of admission and discharge were compared. A multidisciplinary clinical team established criteria by which patients were deemed ineligible to receive any of the recommended therapies. Angiotensin receptor blockers (ARBs were considered an alternative to ACE inhibitors. Results: Prior to hospital admission, 64% of patients were on antiplatelet therapy, 67% were on an ACE inhibitor or ARB, and 71% were on a statin. At the time of discharge, 91% of patients were on an antiplatelet (or not, with an acceptable reason, 77% were on an ACE inhibitor or an ARB (or not, with an acceptable reason, and 85% were on a statin (or not, with an acceptable reason. While new

  1. Geology and natural history of the San Francisco Bay area: A field-trip guidebook (United States)

    Stoffer, Philip W.; Gordon, Leslie C.


    showcase USGS scientific and education resources with self-guided tours of the USGS Library, the Earth Science Information Center (ESIC), the Visitor Center, and various laboratories on the USGS campus and includes a half-day participatory tour of the USGS research vessel the R/V Polaris and the USGS Marine Facility at the Port of Redwood City under the direction of Cynthia L. Brown, Francis Parchaso, and Tara Schraga. Beyond the names mentioned above, a host of USGS and SJSU staff, SJSU students, and NAGT-FWS members contributed to the preparation and orchestration of the conference. We couldn’t have done it alone. Leslie C. Gordon (USGS), Philip W. Stoffer (USGS), and Deborah Harden (SJSU) NAGT-FWS 2001 Fall Field Conference Organizers.

  2. Hydrodynamics of defects in nematic liquid crystal films

    International Nuclear Information System (INIS)

    Kurz, G.


    In this thesis I propose a new theory to deal with the presence of a macroscopic density of defects or disclinations in two-dimensional systems of uniaxial nematic liquid crystal. The static part of the Abelian-Higgs model is the basis for a gauge covariant form of the Frank free energy for distortions in nematics, where the gauge field models the screening due to the presence of the defects. Certain results for vortices in the Abelian-Higgs model are reformulated for use in my theory. The model suggests disclinations with an isotropic core region. The covariant Frank free energy is used to derive a new form of the Ericksen-Leslie equations describing the hydrodynamics off nematics. These equations are set up according to the concept of thermodynamic fluxes and forces. Detailed analytic results are derived for the case where the dynamics is due to director reorientations, but no liquid flow. The hydrodynamic equations are reduced to dynamic equations for disclination points assuming a quasi-static motion in moduli space. The static form of the disclinations is based on solutions in the Bogomol'nyi limit, their quasi-static motion is induced through a deviation from this limit. The resulting equations are valid for a configuration containing disclinations with winding numbers of the same sign. These general equations require a, specific ansatz to yield further results. I consider two regimes, for defects close together and far apart from one another. A set of disclinations with winding numbers of the same sign which are close to one another, i.e. with overlapping cores, can result from disintegration of a larger disclination, and they repel one another. The results for this case predict how the disintegration could occur. The interaction of disclinations, with winding numbers of the same sign, which are far apart from one another is repulsive and decreases exponentially with the distances between them. Two such disclinations move on a straight line where their

  3. Effects of the age class distributions of the temperate and boreal forests on the global CO2 source-sink function (United States)

    Kohlmaier, G. H.; Häger, Ch.; Würth, G.; Lüdeke, M. K. B.; Ramge, P.; Badeck, F.-W.; Kindermann, J.; Lang, T.


    The rôle of the temperate and boreal forests as a global CO2 source or sink is examined, both for the present time and for the next hundred years. The results of the Forest Resource Assessment for 1990 of the Economic Comission for Europe and the Food and Agricultural Organisation of the United Nations (1992) serve as the main database in this study. Out of the estimated total area of approximately 20106 km2 of forests and wooded lands in the temperate and boreal zone only approximately fifty percent is documented within the category of exploitable forests, which are examined in detail here. In this study, a general formalism of the time evolution of an ensemble of forests within an ecological province is developed using the formalism of the Leslie matrix. This matrix can be formulated if the age class dependent mortalities which arise from the disturbances are known. A distinction is made between the natural disturbances by fire, wind throw and insect infestations and disturbances introduced through harvesting of timber. Through the use of Richards growth function each age class of a given biome is related to the corresponding biomass and annual increment. The data reported on the mean net annual increment and on the mean biomass serve to calibrate the model. The difference of the reported net annual increment and annual fellings of approximately 550 106 m3 roundwood correspond to a sink of 210-330 Mt of carbon per year excluding any changes in the soil balance. It could be shown that the present distribution of forest age classes for the United States, Canada, Europe, or the former Soviet Union does not correspond to a quasi-stationary state, in which biomass is accumulated only due to a stimulated growth under enhanced atmospheric CO2 levels. The present CO2 sink function will not persist in the next century, if harvesting rates increase with 0.5% annually or even less. The future state will also be influenced by the effect of the greenhouse climate, the impact

  4. The Effect of Shear Flow on the Isotropic-Nematic Transition in Liquid Crystals. (United States)

    Olmsted, Peter David


    In this thesis I will discuss the effects of shear flow on the Isotropic-Nematic phase transition in liquid crystals. Shear flow has dramatic orienting effects on the rod-like constituents of nematic liquid crystals, with the general effects of (1) inducing order in the high-temperature isotropic phase, and (2) dictating a direction of alignment for the low-temperature nematic phase. Shear flow also imposes a biaxial symmetry on both the high and low temperature phases, thereby changing the nature of the symmetry-breaking at the transition. We develop coupled deterministic dynamical equations for the 5-component nematic order parameter and the fluid velocity, which may be considered generalizations of the Leslie-Ericksen and Navier-Stokes equations, respectively. We examine the stable stationary solutions to these equations to determine the nature of the non-equilibrium phases, and discuss the analogies and differences between this system and equilibrium systems. From homogeneous solutions we obtain a state diagram analogous to that of a Van der Waals fluid, including a two-state region and a discontinuous transition which terminates at a critical point. To resolve the question of the analog of the Maxwell construction to distinguish locally stable states, we construct stable inhomogeneous interfacial states. From an analysis of these states we determine a coexistence line and find exponents characterizing the shape of the coexistence curve and the interface thickness as the critical point is approached. We find mean-field critical behavior, and comment on the possibility of the analogs of spinodal decomposition and nucleation. Finally, we develop a formalism for describing light scattering from biaxial steady state, and investigate the Gaussian level fluctuations about these states. In the vicinity of the critical point we find singular behavior analogous to critical opalescence of a simple fluid at its critical point. We also find anisotropic correlations at the

  5. Systematic review and network meta-analysis of stroke prevention treatments in patients with atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Tawfik A


    Full Text Available Amy Tawfik,1,2 Joanna M Bielecki,2 Murray Krahn,1,2 Paul Dorian,3,4 Jeffrey S Hoch,1,3,5 Heather Boon,1 Don Husereau,6 Petros Pechlivanoglou2 1Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, 2Toronto Health Economics and Technology Assessment (THETA Collaborative, University of Toronto, 3Centre for Excellence in Economic Analysis Research (CLEAR, Li Ka Shing Knowledge Institute, St Michael’s Hospital, 4Department of Medicine and Cardiology, University of Toronto, 5Pharmacoeconomics Research Unit, Cancer Care Ontario, Toronto, ON, 6Institute of Health Economics, Edmonton, AB, Canada Background: In the last 4 years, four novel oral anticoagulants have been developed as alternatives to warfarin and antiplatelet agents for stroke prevention in atrial fibrillation (AF patients. The objective of this review was to estimate the comparative effectiveness of all antithrombotic treatments for AF patients.Materials and methods: Data sources were Medline Ovid (1946 to October 2015, Embase Ovid (1980 to October 2015, and the Cochrane Central Register of Controlled Trials (­CENTRAL, Issue 9, 2015. Randomized controlled trials of AF patients were selected if they compared at least two of the following: placebo, aspirin, aspirin and clopidogrel combination therapy, adjusted-dose warfarin (target international normalized ratio 2.0–3.0, dabigatran, rivaroxaban, apixaban, and edoxaban. Bayesian network meta-analyses were conducted for outcomes of interest (all stroke, ischemic stroke, myocardial infarction, overall mortality, major bleeding, and intracranial hemorrhage.Results: Based on 16 randomized controlled trials of 96,826 patients, all oral anticoagulants were more effective than antiplatelet agents at reducing the risk of ischemic stroke and all strokes. Compared to warfarin, dabigatran 150 mg (rate ratio 0.65, 95% credible interval 0.52–0.82 and apixaban (rate ratio 0.82, 95% credible interval 0.69–0.97 reduced the risk of

  6. Listening to those on the frontline: service users' experiences of London tuberculosis services

    Directory of Open Access Journals (Sweden)

    Boudioni M


    Full Text Available Markella Boudioni, Susan McLaren, Ruth Belling, Leslie WoodsInstitute for Leadership and Service Improvement, Faculty of Health and Social Care, London South Bank University, London, UKAim: To explore tuberculosis (TB service users' experiences and satisfaction with care provision.Background: Thirty-nine percent of all new UK TB cases occur in London. Prevalence varies considerably between and within boroughs. Overall, research suggests inadequate control of London's TB transmission; TB has become a health care priority for all London Primary Care Trusts. Service users' experiences and satisfaction with care provision have not been explored adequately previously.Methods: A qualitative research design, using semi-structured face-to-face interviews was used. Ten service users, purposively selected in key risk groups across London, were interviewed. All interviews were digitally recorded with users' permission, transcribed verbatim, and analyzed thematically.Results: Participants were treated in local hospitals for 6–12 months. Treatment was administered by TB nurses to inpatients and outpatients receiving directly observed therapy in consultation with medical staff and home visits for complex cases. Two participants did not realize the importance of compliance. Overall, they were satisfied with many TB services' aspects, communication, and service organization. Early access, low suspicion index amongst some GPs, and restricted referral routes were identified as service barriers. Other improvement areas were information provision on drug side effects, diet, nutritional status, and a few health professionals' attitudes. The effects on people varied enormously from minimal impact to psychological shock; TB also affected social and personal aspects of their life. With regard to further support facilities, some positive views on managed accommodation by TB-aware professionals for those with accommodation problems were identified.Conclusion: This

  7. Dispersión sísmica por presencia de capas someras de alta velocidad: modelamiento con diferencias finitas

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    Céspedes Sandra


    Full Text Available

    Through finite difference modelling, we studied the effects of seismic scattering due near surface high velocity layers, with varied contrasts and thickness, and their influence on seismic data. Despite conventional methods to eliminate noise mainly based in a mathematical approach, i.e., F-K analysis, Radon transform, we apply a deterministic scheme based on the modeling of wave propagation, generating the unwanted signals (Ernst et al., 1998; Blonk et al., 1995; Blonk and Hermann, 1994.

    The detailed understanding of the backscattering phenomenon allows to discern what can be considered noise and therefore to define attenuation' s strategies (Lamer et al., 1983. In presence of near surface high velocity layers, part of the original seismic energy is scattered in these layers and only a smaller fraction is transmitted to the Earth' s interior, generating coherent noise that masks the information comming from the deeper reflectors (Leslie and Evans, 1999. A 20 model was designed to obtain synthetic seismograms. The simulation shows the scattering mechanism related with velocity inversions in the near surface layers, allowing to characterize their influence on seismic records. The unwanted signal is subtracted from that considered information. The results obtained in this work are bounded to the analysis of synthetic data.

    Mediante el modelamiento con diferencias finitas, se

  8. The use of the swept area method for assessing the seabob shrimp Xiphopenaeus kroyeri (Heller, 1862 biomass and removal rates based on artisanal fishery-derived data in southern Brazil: using depletion models to reduce uncertainty El uso del método de area de barrido para la evaluación de la biomasa y tasas de remoción del camarón Xiphopenaeus kroyeri (Heller, 1862 a partir de datos de la pesca artesanal en el sur de Brasil: la utilización de modelos de reducción de stock para disminuir incertidumbres

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    Paulo R Pezzuto


    Full Text Available The seabob shrimp (Xiphopenaeus kroyeri represents an important fishing resource for artisanal fishermen in coastal areas of southern Brazil. Stock assessments of this species ha ve generally relied on biomass dynamics models as applied to CPUE time-series, which (a are only available for a small offshore fraction of the exploited population and (b does not comprise patterns of the shallowest artisanal fishing grounds. This work explores the use of extensive catch and effort data derived from a small-scale trawl fishery to obtain swept-area estimates of abundance and removal rates in a limited coastal area of southern Brazil (Tijucas Bay, Santa Catarina State, 27°15'S-48°33'W. Data were obtained from 7,198 fishing trips monitored at the fishing communities between June 2004 and August 2005. Because three parameters of the swept-area equation (i.e. trawl velocity, catch efficiency and wing spread were unknown, they were defined through a stochastic procedure and calibrated by estimates produced by a Leslie depletion model applied to concurrent catches obtained in one fishing ground. A 21.7% removal rate was estimated for the period June 2004-January 2005; this increased to nearly 34% between February and July 2005. This removal scenario predicted that a five-month fishery would suffice to remo ve 90% of the biomass available in the Tijucas Bay, nearing the 87% CPUE reduction observed in the same period. Whereas abundance and harvest rate estimates were likely affected by inadequate knowledge of the swept-area equation parameters, the similarity of these estimates with relative abundance indexes supports the convenience of the proposed method and justifies future efforts to improve its accuracy.El camarón (Xiphopenaeus kroyeri representa un importante recurso para pescadores artesanales en areas costeras del sur de Brasil. Evaluaciones de stock de esta especie generalmente resultan de modelos de dinámica de biomasa aplicados a series

  9. Dossiê - 3º Simpósio Brasileiro de Comunicação Científica – SBCC, 2012.

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    Márcio Matias


    Full Text Available Márcio Matias (CIN/UFSC Moisés Lima Dutra (CIN/UFSC O 3º Simpósio Brasileiro de Comunicação Científica (SBCC – Perspectivas em Acesso Aberto – Cenários para 2020, foi realizado na Universidade Federal de Santa Catarina (UFSC, no campus Reitor João David Ferreira Lima, em Florianópolis, nos dias 5 e 6 de junho de 2012. O objetivo do evento foi de proporcionar à comunidade acadêmica discussões sobre a comunicação científica com foco nas perspectivas de acesso aberto/livre e preservação digital. O SBCC é uma iniciativa do Departamento de Ciência da Informação (CIN e do Programa de Pós-Graduação em Ciência da Informação (PGCIN da UFSC, e no início dos trabalhos, a Comissão Organizadora convidou o Professor Dr. Hélio Kuramoto, do IBICT, para compor o Comitê Científico do evento. Nesta edição, além de abrir a recepção de trabalhos científicos sobre os temas de acesso aberto e preservação digital, o evento contou com a presença dos seguintes pesquisadores nacionais e estrangeiros para proferir palestras e participar de mesas-redondas sobre estes temas: •\tElena Maceviciute - Universidade de Boras (Suécia •\tLeslie Chan - Universidade de Toronto (Canadá •\tSely Costa - Universidade de Brasília (UnB •\tHélio Kuramoto - Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT •\tNelson Pretto - Universidade Federal da Bahia (UFBA/ Sociedade Brasileira para o Progresso da Ciência (SBPC •\tSolange Maria dos Santos - Membro do Colegiado do Scielo Às nove horas do dia cinco de junho de 2012, terça-feira, a abertura do 3º SBCC foi realizada no auditório da reitoria. A cerimônia de abertura contou com a presença das seguintes autoridades da UFSC: Professora Dra. Joana Maria Pedro, Pró-Reitora de Pós-Graduação, Professor Dr. Jamil Assereuy Filho, Pró-Reitor de Pesquisa, da Professora Dra. Vera Lúcia Bazzo, Diretora do Centro

  10. Dossiê - 3º Simpósio Brasileiro de Comunicação Científica – SBCC, 2012.

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    Moisés Lima Dutra Correio


    Full Text Available Márcio Matias (CIN/UFSC Moisés Lima Dutra (CIN/UFSC O 3º Simpósio Brasileiro de Comunicação Científica (SBCC – Perspectivas em Acesso Aberto – Cenários para 2020, foi realizado na Universidade Federal de Santa Catarina (UFSC, no campus Reitor João David Ferreira Lima, em Florianópolis, nos dias 5 e 6 de junho de 2012. O objetivo do evento foi de proporcionar à comunidade acadêmica discussões sobre a comunicação científica com foco nas perspectivas de acesso aberto/livre e preservação digital. O SBCC é uma iniciativa do Departamento de Ciência da Informação (CIN e do Programa de Pós-Graduação em Ciência da Informação (PGCIN da UFSC, e no início dos trabalhos, a Comissão Organizadora convidou o Professor Dr. Hélio Kuramoto, do IBICT, para compor o Comitê Científico do evento. Nesta edição, além de abrir a recepção de trabalhos científicos sobre os temas de acesso aberto e preservação digital, o evento contou com a presença dos seguintes pesquisadores nacionais e estrangeiros para proferir palestras e participar de mesas-redondas sobre estes temas: • Elena Maceviciute - Universidade de Boras (Suécia • Leslie Chan - Universidade de Toronto (Canadá • Sely Costa - Universidade de Brasília (UnB • Hélio Kuramoto - Instituto Brasileiro de Informação em Ciência e Tecnologia (IBICT • Nelson Pretto - Universidade Federal da Bahia (UFBA/ Sociedade Brasileira para o Progresso da Ciência (SBPC • Solange Maria dos Santos - Membro do Colegiado do Scielo Às nove horas do dia cinco de junho de 2012, terça-feira, a abertura do 3º SBCC foi realizada no auditório da reitoria. A cerimônia de abertura contou com a presença das seguintes autoridades da UFSC: Professora Dra. Joana Maria Pedro, Pró-Reitora de Pós-Graduação, Professor Dr. Jamil Assereuy Filho, Pró-Reitor de Pesquisa, da Professora Dra. Vera Lúcia Bazzo, Diretora do Centro de Ciências da Educação, da Professora Dra. Gleisy

  11. Rattraper le nouvel Occident : « L’initiative d’excellence » allemande, les études régionales et la re-production des inégalités Alemania : Excelencia alemana y Areas de Estudios o como traer al eurocentrismo por la puerta de atrás. Catching Up with the (New West: German “Excellence Initiative,” Area Studies and the Re-Production of Inequality

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    Manuela Boatcă


    Full Text Available AbstractIn the wake of the recent university reforms, the new academic division of labor in Germany has subserviently followed the U.S.-model of creating a rift between research and teaching universities by establishing on the one hand so-called “elite universities” that benefit from considerable state funding and on the other hand trying to reduce the rest to pedagogical carbon copies of standard curricula that can only award bachelor‘s or at most master‘s degrees and where the teaching load allows (almost no research.The so-called “excellence initiative”, an evaluation process taking place between 2006 and 2007, in the course of which 9 universities  - among which the Free University of Berlin, the University of Munich, and the University of Heidelberg - were designated as “elite universities”, represents Germany‘s hitherto clearest and most highly institutionalized example of a state policy aimed at confining research to specialized institutions, such as was already the case with the Max Planck institutes, the Leibniz institutes and the Fraunhofer societies founded in the 1970s and 1980s. However, while earlier steps in this direction only created a wider array of employment options for researchers, the argument of this paper is that the excellence initiative represents what has been called a process of “indirect commercialization” (Reinhard Kreckel or an instance of “academic capitalism” (Slaughter/Leslie of/in the Western European university system, which traditionally relied on state financing and state control of university finances. To this end, the paper proceeds in two steps: First, following Reinhard Kreckel‘s argument that neoliberal globalization exerts new economic and fiscal pressures on the state that are then passed on to the higher education systems depending on them, the paper looks at how the new elite discourse of German higher education is producing new structures of exclusion instead of the

  12. Exploring the meaning of practicing classroom inquiry from the perspectives of National Board Certified Science Teachers (United States)

    Karaman, Ayhan

    Inquiry has been one of the most prominent terms of the contemporary science education reform movement (Buck, Latta, & Leslie-Pelecky, 2007; Colburn, 2006; Settlage, 2007). Practicing classroom inquiry has maintained its central position in science education for several decades because science education reform documents promote classroom inquiry as the potential savior of science education from its current problems. Likewise, having the capabilities of teaching science through inquiry has been considered by National Board for Professional Teaching Standards [NBPTS] as one of the essential elements of being an accomplished science teacher. Successful completion of National Board Certification [NBC] assessment process involves presenting a clear evidence of enacting inquiry with students. Despite the high-profile of the word inquiry in the reform documents, the same is not true in schools (Crawford, 2007). Most of the science teachers do not embrace this type of approach in their everyday teaching practices of science (Johnson, 2006; Luera, Moyer, & Everett, 2005; Smolleck, Zembal-Saul, & Yoder, 2006; Trumbull, Scarano, & Bonney, 2006). And the specific meanings attributed to inquiry by science teachers do not necessarily match with the original intentions of science education reform documents (Matson & Parsons, 2006; Wheeler, 2000; Windschitl, 2003). Unveiling the various meanings held by science teachers is important in developing better strategies for the future success of science education reform efforts (Jones & Eick, 2007; Keys & Bryan, 2001). Due to the potential influences of National Board Certified Science Teachers [NBCSTs] on inexperienced science teachers as their mentors, examining inquiry conceptions of NBCSTs is called for. How do these accomplished practitioners understand and enact inquiry? The purpose of this dissertation research study was twofold. First, it investigated the role of NBC performance assessment process on the professional development

  13. NASA Activity Update for the 2013 Unmanned Vehicle Systems International (UVSI) Yearbook (United States)

    Bauer, Jeffrey E.


    This year s report offers a high level perspective on some of the UAS related activities in which NASA is involved, both internal and external to the agency. Internally, NASA issued UAS operational policy on certification of NASA UAS and aircrew. A team of NASA UAS experts and operators analyzed all current procedures and best practices to design the policy. An update to the agencies Aircraft Operations Management Manual incorporated a new chapter to address UAS planning, preflight operations, flight operations, flight crew requirements, airworthiness and flight safety reviews. NASA UAS are classified into three categories based on weight and airspeed. Aircrews, including observers, are classified by how they interface with the UAS, and the policy defines qualifications, training, and currency. The NASA flight readiness approval process identifies risks and mitigations in order to reduce the likelihood and/or consequence of the risk to an acceptable level. The UAS operations process incorporates all aspects of airworthiness, flight standards and range safety exactly the same processes used for NASA manned aircraft operations. NASA has two internal organizations that routinely operate UAS. The Science Mission Directorate utilizes UAS as part of its Airborne Science Program and is the most frequent operator of NASA UAS in both national and international airspace. The Aeronautics Research Mission Directorate conducts UAS flight operations in addition to conducting research important to the UAS community. This past year the Science Mission Directorate supported the Hurricane and Severe Storm Sentimental (HS3) Mission with two NASA Global Hawk platforms. HS3 is a five-year mission specifically targeted to investigate the processes that underlie hurricane formation. During the 2012 portion of this mission the Global Hawk overflew hurricanes Leslie and Nadine in the Atlantic Ocean completing 6 flights and accumulating more than 148 flight hours. Another multi-year mission

  14. A Learned Society's Perspective on Publishing. (United States)

    Suzuki, Kunihiko; Edelson, Alan; Iversen, Leslie L; Hausmann, Laura; Schulz, Jörg B; Turner, Anthony J


    Scientific journals that are owned by a learned society, like the Journal of Neurochemistry (JNC), which is owned by the International Society for Neurochemistry (ISN), benefit the scientific community in that a large proportion of the income is returned to support the scientific mission of the Society. The income generated by the JNC enables the ISN to organize conferences as a platform for members and non-members alike to share their research, supporting researchers particularly in developing countries by travel grants and other funds, and promoting education in student schools. These direct benefits and initiatives for ISN members and non-members distinguish a society journal from pure commerce. However, the world of scholarly publishing is changing rapidly. Open access models have challenged the business model of traditional journal subscription and hence provided free access to publicly funded scientific research. In these models, the manuscript authors pay a publication cost after peer review and acceptance of the manuscript. Over the last decade, numerous new open access journals have been launched and traditional subscription journals have started to offer open access (hybrid journals). However, open access journals follow the general scheme that, of all participating parties, the publisher receives the highest financial benefit. The income is generated by researchers whose positions and research are mostly financed by taxpayers' or funders' money, and by reviewers and editors, who frequently are not reimbursed. Last but not least, the authors pay for the publication of their work after a rigorous and sometimes painful review process. JNC itself has an open access option, at a significantly reduced cost for Society members as an additional benefit. This article provides first-hand insights from two former Editors-in-Chief, Kunihiko Suzuki and Leslie Iversen, about the history of JNC's ownership and about the difficulties and battles fought along the way to

  15. Seven-microRNA panel for lung adenocarcinoma early diagnosis in patients presenting with ground-glass nodules

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    He Y


    Full Text Available Yayi He,1,2,* Yang Yang,3,* Peng Kuang,1 Shengxiang Ren,1 Leslie Rozeboom,2 Christopher J Rivard,2 Xuefei Li,4 Caicun Zhou,1 Fred R Hirsch2 1Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; 3Department of Surgery, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, 4Department of Lung Cancer and Immunology, Shanghai Pulmonary Hospital, Tongji University Medical School Cancer Institute, Tongji University School of Medicine, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: MicroRNA (miRNA expression is correlated with tumor histology, differentiation, invasiveness and treatment outcome. We aimed to identify miRNAs whose differential expression might enable early diagnosis of lung adenocarcinoma in patients presenting with ground-glass nodules (GGNs.Methods: To identify potential miRNAs of interest, we analyzed the miRNA expression profile of tumor and adjacent non-para-tumor tissue in three participants by next-generation sequencing (NGS. We then assessed the expression levels of the miRNAs of interest in 73 lung adenocarcinomas presenting with GGNs with matched adjacent non-tumor tissue by quantitative real-time polymerase chain reaction (qRT-PCR. We also detected the miRNA panel in 66 lung benign diseases and 66 lung adenocarcinomas presenting with GGN lesion tissues by qRT-PCR. Target genes of our selected miRNA panel were predicted using Miranda with default parameters.Results: Twenty-three miRNAs showed differential expression between tumor and adjacent non-tumor tissue by NGS. Five miRNAs exhibited higher expression in tumor tissue compared to adjacent non-tumor tissue (P

  16. Latest climate changes in Romania :tornadoes (United States)

    Pop, Elena


    " that eat and spit out roofs, animals, trucks and concrete road poles. I have minutely searched with my students all the data of that tornado, the direction of wind gusts, we have calculated the force of the impact by studying the photos taken on that occasion. I have also done some research on other tornadoes that have taken place In Movilita and Brezoaele the past years. I have studied the increase of the centrifugal force and that of Coriolis in the context of repetition of such dangerous atmospheric phenomena that showed their apparition as ten per year in Romania. Therefore the average Coriolis parameter is 10-4 s-1, for a typical atmospheric speed of 10 m/s (22 mph) the radius is 100 km (62 mi), with a period of about 17 hours. The lowering of the air pressure occurring on such occasions has been one of my concerns as well the the speed of the cloud column rotation. All these phenomena are the effect of the climate change occurring all over our Planet due to pollution. As you can see the devastation produced by such extreme climate lead to spontaneous floods and later desertification on the south-eastern part of our country. References : 1. Craciun, Cristina, Bala, Bogdan, Tornadele din Romania, 2. Bell, Aurora, Tornadele in Romania, 3. Lemon, R. Leslie, Stan-Sion, Aurora, Soci , Cornel, Corduneanu, Elena, A strong, long -track, Romanian tornado, Author : Mrs. Elena Pop, Science teacher at "Lucian Blaga" Secondary School, Ocna Mures, Romania

  17. YouTube Videos as a Source of Information About Clinical Trials: Observational Study. (United States)

    Hillyer, Grace Clarke; MacLean, Sarah A; Beauchemin, Melissa; Basch, Corey H; Schmitt, Karen M; Segall, Leslie; Kelsen, Moshe; Brogan, Frances L; Schwartz, Gary K


    provided information on many aspects of trials; however, individual videos tended to focus on selected topics with varying levels of detail. Cancer clinical trial videos were more emotional in style and positive in tone and provided information on the important topics of cost and communication. Patients are encouraged to verify and supplement YouTube video information in consultations with their health care professionals to obtain a full and accurate picture of cancer clinical trials to make an adequately informed decision about participation. ©Grace Clarke Hillyer, Sarah A MacLean, Melissa Beauchemin, Corey H Basch, Karen M Schmitt, Leslie Segall, Moshe Kelsen, Frances L Brogan, Gary K Schwartz. Originally published in JMIR Cancer (, 26.06.2018.

  18. Finding time, stopping the frenzy. (United States)

    Perlow, L A


    While the deleterious consequences of long hours of work for individuals, families and communities have previously been documented, the assumption that long hours are necessary to get the work done, especially in a world where speed is becoming increasingly critical to corporate success, has prompted little challenge. So Leslie Perlow, an assistant professor of business at the University of Michigan, Ann Arbor, set out to explore the necessity for the seemingly endless workdays that so many postindustrial settings require. Her study of a group of software engineers at a Fortune 500 company--identified only as the Ditto Corp--is detailed in her book, Finding Time: How Corporations, Individuals, and Families Can Benefit from New Work Practices (Cornell University Press, 1997). Perlow's research reveals a "sad and all too common tale" of workers harried by competing demands, frequent interruptions and shifting deadlines. To meet the firm's expectations, the engineers she studied sacrificed home life, focused on individual tasks to the detriment of group goals and, in many cases, eventually lost any enthusiasm they'd had for working for the company. There has been some recognition that stress and burnout may be bad for a corporation as employees become less committed, decide to leave or get fired and that this kind of turnover can hurt the firm in the longer term. But Perlow documented the additional, and quite significant, shorter-term costs to the corporation of the current way of using time at work. What she found was a "vicious time cycle:" Time pressures led to a crisis mentality, which led to "individual heroics." That is, I'll do whatever it takes to do my job--even if it means interrupting you while you try to do yours. For the engineers Perlow studied, the lack of helping, the constant interruptions and the perpetual crises--clearly illustrated by the daily log that appears on page 34--made it harder to develop products. Ultimately, they worked long hours to


    Directory of Open Access Journals (Sweden)

    Mónica Viviana Norambuena


    Full Text Available El presente trabajo aborda las transformaciones espaciales sufridas en los asentamientos humanos del área cordillerana de la provincia de Santa Cruz producto de la actividad turística particularmente en los del departamento Lago Argentino. El Chaltén y El Calafate son los asentamientos que desarrollan el turismo como base de su economía. El incremento de la actividad se debe a los cambios en el sistema productivo provincial en las últimas décadas, netamente ganadero en El Calafate a principios y mediados del siglo XX. Asimismo, las razones geopolíticas que dieron origen a El Chaltén, hoy han pasado a ser parte de su historia, ya que el turismo es la principal actividad que desarrolla el asentamiento. Esta actividad en la provincia se ha incrementado a partir de la década del 1990 impulsada por los Estados nacional, provincial y municipal que llevan adelante políticas de promoción en el sector. Por otra parte, en estos asentamientos, el auge turístico trae aparejado consecuencias sociales y ambientales dado el crecimiento acelerado de los mismos en cuanto a la población que se radica, la falta de infraestructura básica y equipamiento son los principales sin dejar de mencionar la especulación inmobiliaria. El objetivo del presente trabajo es analizar las transformaciones espaciales en los asentamientos del oeste de la provincia de Santa Cruz particularmente los del departamento Lago Argentino a partir del incremento de la actividad turística en el área en las últimas décadas. Teóricamente, se recurrió a Roberto C. Boullón en Planificación del espacio turístico, a diferentes apuntes de Eduardo Salinas Chávez, y a Leslie Scovenna en el Gran Libro de Santa Cruz entre otras. Se utilizaron diversas páginas en Internet información proporcionada por la Subsecretaria de Turismo de la Provincia de Santa Cruz. Para el análisis de las transformaciones se realizo una caracterización del emplazamiento de los asentamientos en cuesti

  20. Candem projects 1965-1980. Vida privada y espacio doméstico

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    Luz Sempere Sánchez


    domestic space to the changes in society brings about the need to constantly redefine it. This space, conceived as the cell of privacy, is exposed to all the changes that occur in the structure of families. It is also exposed to all the technological advances, which directly influence it by being "goods" available to everyone. In our present time, where even internet technology is already taking a leap into virtual space, a debate regarding the characteristics of the home is absolutely necessary.

    This article focuses on the following projects: Branch Hill, (1973. G. Benson and A. Forsyth, architects, Maiden Lane, 1976-1983 (G. Benson and A. Forsyth, architects, Alexandra Road, (1968-1979, Neave Brown, architect and Brunswick Centre (1968-1972. Sir Leslie Martin and Patrick Hodgkinson, architects. Given their specific characteristics, these projects are the most relevant to explain and transmit the construction of contemporary domestic space and the private life inside it. From this analysis, based on the study of privacy and the absence of domesticity, we hope to understand how this contemporary domestic space is built, as well as its relationship to the city. This article will compare the main concepts analyzed in each project, and will question the relationships between interior and exterior, and semi-private and semi-public.


  1. Relationship between leukotriene-modifying agent prescriptions dispensed and rate of suicide deaths by county in the US

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    Schumock GT


    Full Text Available Glen T Schumock1, Robert D Gibbons2, Todd A Lee1,3,4,6, Min J Joo4, Robert J Valuck5, Leslie T Stayner61Center for Pharmacoeconomic Research, and Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA; 2Center for Health Statistics, and Departments of Medicine and Health Studies, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA; 3Center for Management of Complex Chronic Care, Hines VA Hospital, Hines, IL, USA; 4Section of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, College of Medicine, University of Illinois at Chicago, Chicago, IL, USA; 5Department of Clinical Pharmacy, School of Pharmacy, University of Colorado, Aurora, CO, USA; 6Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USABackground: The US Food and Drug Administration has issued warnings about a potential link between leukotriene receptor-modifying agents (LTMA and suicide. These warnings are based on case reports and there is controversy about the association. While spontaneous reporting of suicide-related events attributed to LTMA has risen dramatically, these data may be biased by the warnings. The objective of this study was to explore the relationship between LTMA and suicide deaths using event data preceding the Food and Drug Administration warnings.Methods: We conducted a mixed-effects Poisson regression analysis of the association between LTMA prescriptions dispensed and suicide deaths at the county level. Counts of suicide deaths in each US county, stratified by race, age group, gender, and year were obtained from the National Center for Health Statistics for the period January 1, 1999 to December 31, 2006. Counts of LTMA prescriptions dispensed in each US county were obtained from IMS Health Incorporated. The model estimated the overall suicide rate conditional on LTMA use, adjusted for age, gender, race, year

  2. "Thanks for Letting Us All Share Your Mammogram Experience Virtually": Developing a Web-Based Hub for Breast Cancer Screening. (United States)

    Galpin, Adam; Meredith, Joanne; Ure, Cathy; Robinson, Leslie


    discussion. Health professionals and service users expressed the same broad concerns, but there were subtle differences in their opinions. Importantly, the themes were triangulated between the Facebook discussions and the survey data, supporting the validity of an online user design group. Online user design groups afford a useful method for understanding stakeholder needs. In contrast to focus groups, they afford access to users from diverse geographical locations and traverse time constraints, allowing more follow-ups to responses. The use of Facebook provides a familiar and naturalistic setting for discussion. Although we acknowledge the limitations in the sample, this approach has allowed us to understand the views of stakeholders in the user-centered design of the WoMMeN hub for breast cancer screening. ©Adam Galpin, Joanne Meredith, Cathy Ure, Leslie Robinson. Originally published in JMIR Cancer (, 27.10.2017.

  3. Selected abstracts from the Breastfeeding and Feminism International Conference 2016

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    Lisa H. Amir


    Full Text Available Table of contents A1. Infant feeding and poverty: a public health perspective in a global context Lisa H. Amir A2. Mothers’ experiences with galactagogues for lactation: an exploratory cross sectional study Alessandra Bazzano, Shelley Thibeau, Katherine P. Theall A3. The motherhood journey and breastfeeding: from self-efficacy to resilience and social stigma Anna Blair, Karin Cadwell A4. Breastfeeding as an evolutionary adaptive behavior Emily A. Bronson A5. Conflict-of-interest in public health policy: as real as that logo on your website Elizabeth C. Brooks A6. Co-opting sisterhood and motherhood: behind the scenes of Similac’s aggressive social media campaigns Jodine Chase A7. The exclusion of women from the definition of exclusive breastfeeding Ellen Chetwynd, Rebecca Costello, Kathryn Wouk A8. Healthy maternity policies in the workplace: a state health department’s experience with the “Bring Your Infant to Work” program Lindsey Dermid-Gray A9. Implications for a paradigm shift: factors related to breastfeeding among African American women Stephanie Devane-Johnson, Cheryl Woods Giscombe, Miriam Labbok A10. Social experiences of breastfeeding: building bridges between research and policy: an ESRC-funded seminar series in the UK Sally Dowling A11. Manager’s perspectives of lactation breaks Melanie Fraser A12. The challenging second night: a dialogue from two perspectives Jane Grassley, Deborah McCarter-Spaulding, Becky Spencer A13. The role of lactation consultants in two council breastfeeding services in Melbourne, Australia – some preliminary impressions Jennifer Hocking, Pranee Liamputtong A14. Integrating social marketing and community engagement concepts in community breastfeeding programs Sheree H. Keitt, Harumi Reis-Reilly A15. What happens before and after the maternity stay? Creating a community-wide Ten Steps approach Miriam Labbok A16. #RVABREASTFEEDS: cultivating a breastfeeding-friendly community Leslie Lytle A17

  4. Book Reviews

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    Redactie KITLV


    Full Text Available -Leslie G. Desmangles, Joan Dayan, Haiti, history, and the Gods. Berkeley: University of California Press, 1995. xxiii + 339 pp. -Barry Chevannes, James T. Houk, Spirits, blood, and drums: The Orisha religion in Trinidad. Philadelphia: Temple University Press, 1995. xvi + 238 pp. -Barry Chevannes, Walter F. Pitts, Jr., Old ship of Zion: The Afro-Baptist ritual in the African Diaspora. New York: Oxford University Press, 1993. xvi + 199 pp. -Robert J. Stewart, Lewin L. Williams, Caribbean theology. New York: Peter Lang, 1994. xiii + 231 pp. -Robert J. Stewart, Barry Chevannes, Rastafari and other African-Caribbean worldviews. London: Macmillan, 1995. xxv + 282 pp. -Michael Aceto, Maureen Warner-Lewis, Yoruba songs of Trinidad. London: Karnak House, 1994. 158 pp.''Trinidad Yoruba: From mother tongue to memory. Tuscaloosa: University of Alabama Press, 1996. xviii + 279 pp. -Erika Bourguignon, Nicola H. Götz, Obeah - Hexerei in der Karibik - zwischen Macht und Ohnmacht. Frankfurt am Main: Peter Lang, 1995. 256 pp. -John Murphy, Hernando Calvo Ospina, Salsa! Havana heat: Bronx Beat. London: Latin America Bureau, 1995. viii + 151 pp. -Donald R. Hill, Stephen Stuempfle, The steelband movement: The forging of a national art in Trinidad and Tobago. Philadelphia: University of Pennsylvania Press, 1995. xx + 289 pp. -Hilary McD. Beckles, Jay R. Mandle ,Caribbean Hoops: The development of West Indian basketball. Langhorne PA: Gordon and Breach, 1994. ix + 121 pp., Joan D. Mandle (eds -Edmund Burke, III, Lewis R. Gordon ,Fanon: A critical reader. Oxford: Blackwell, 1996. xxi + 344 pp., T. Denean Sharpley-Whiting, Renée T. White (eds -Keith Alan Sprouse, Ikenna Dieke, The primordial image: African, Afro-American, and Caribbean Mythopoetic text. New York: Peter Lang, 1993. xiv + 434 pp. -Keith Alan Sprouse, Wimal Dissanayake ,Self and colonial desire: Travel writings of V.S. Naipaul. New York : Peter Lang, 1993. vii + 160 pp., Carmen Wickramagamage (eds

  5. Contemporary strategic management approach in the defense system by U.S. methodology concept

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    Veselin I. Mrdak


    Full Text Available The paper wants to emphasize the importance of contemporary strategic management approachs in the defense system. Displays the work of American author Leslie Lewis and C. Robert Roll "Strategy-to- tasks: a methodology for resource allocation and management". It were used by parts of the discussion above, in order to describe the strategy-to-tasks methodology for planning, programming and budgeting system (PPBS. In developed Western countries adopted some elements of strategic management to determine and monitor the execution of strategic plans in the defense system. This trend is spreading to other countries as a result of the necessity of obeying certain methodological and technological achievements. The uncritical acceptance of a strategic management approach can cause great confusion and problems, and the terminology and scientific explanation for this trend is of great importance. Introduction PPBS is a resource management framework based on force planning concept. It was developed at the lRand Company during the late eighties and is adapted to the special needs of several DoD organization. The planning, programming and budgeting system (PPBS PPBS is DoD`ş primary system for planning and managing defense resources. It links the overall U.S. national security strategy to specific programs. It was designed to facilitate fiscally-constrained planning, programming and budgeting in terms of complete programs (i.e. forces and systems rather than through artificial budget categories. The goal is to determine forces, systems and program costs. Strategy-to-tasks and the PPBS The Strategy-To-Tasks methodology, regardless of its application, it must be consistent and supportive of each phase of the PPBS. This section describes the basics frameworks of which are adapted to resource allocation and management activities for the Special Operations Command (USSOCOM. The authors have used it during the various phases of the PPBS. The National Security

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV


    . Cambridge: Cambridge University Press, 1993. xxii + 322 pp. -Robert Fatton, Jr., Brian Weinstein ,Haiti: The failure of politics. New York: Praeger, 1992. ix + 203 pp., Aaron Segal (eds -Uli Locher, Michel S. Laguerre, The military and society in Haiti. Knoxville: University of Tennessee Press, 1993. x + 223 pp. -Paul E. Brodwin, Leslie G. Desmangles, The faces of the Gods: Vodou and Roman Catholicism in Haiti. Chapel Hill: University of North Carolina Press, 1992. xiii + 218 pp. -Marian Goslinga, Enid Brown, Bibliographical guide to Caribbean mass communication. John A. Lent (comp.. Westport CT: Greenwood Press, 1992. xi + 301 pp.''Suriname and the Netherlands Antilles: An annotated English-language bibliography. Metuchen NJ: Scarecrow Press, 1992. xi + 276 pp. -Jay B. Haviser, F.R. Effert, J.P.B. de Josselin de Jong, curator and archaeologist: A study of his early career (1910-1935. Leiden: Centre of Non-Western studies, University of Leiden, 1992. v + 119 pp. -Hans van Amersfoort, Anil Ramdas, De papegaai, de stier en de klimmende bougainvillea. Essays. Amsterdam: De Bezige Bij, 1992. -Ineke van Wetering, Deonarayan, Curse of the Devtas. Paramaribo: J.J. Buitenweg, 1992. v + 103 pp. -Ineke van Wetering, G. Mungra, Hindoestaanse gezinnen in Nederland. Leiden: Centrum voor Onderzoek Maatschappelijke Tegenstellingen, Rijksuniversiteit Leiden, 1990. 313 pp. -J.M.R. Schrils, Alex Reinders, Politieke geschiedenis van de Nederlandse Antillen en Aruba 1950-1993. Zutphen: Walburg Pers, 1993. 430 pp. -Gert Oostindie, G.J. Cijntje ,Stemmen OK, maar op wie? Delft: Eburon, 1991. 150 pp., A. Nicatia, F. Quirindongo (eds -Genevieve Escure, Donald Winford, Predication in Caribbean English Creoles. Amsterdam & Philadelphia: John Benjamins, 1993, viii + 419 pp. -Jean D'Costa, Lise Winer, Trinidad and Tobago. Amsterdam & Philadelphia: John Benjamins, 1993. xi + 369 pp. (plus cassette

  7. Obituary: Lawrence Hugh Aller, 1913-2003 (United States)

    Kaler, James B.


    The announcement still lies in my inbox: ``Lawrence Aller died last Sunday." On 16 March 2003, one of the world's fine astronomers passed away at the age of 89, leaving behind a legacy that will ripple as long as there are students of the celestial science, one that incorporated observation, theory, education, care, decency, and kindness. Lawrence was born in the humblest of conditions in Tacoma, Washington, on 24 September 1913. His mother, Lella (Belle) Allen, was a homemaker and his father Leslie Aller, was an occassional printer and gold prospector who thought that the use of the mind was a waste of time. With fierce persistence and dedication, Lawrence pulled off a feat that would probably not be possible now: getting into college without having finished high school, the result of being dragged to work in his father's primitive gold mining camp. His interest, sparked by leaflets from the Astronomical Society of the Pacific and by Russell, Dugan, and Stewart's venerable textbook, led him to a correspondence, and finally a meeting, with Donald Menzel of Harvard, who persuaded the admissions director of the University of California at Berkeley to admit him in 1932. From there, Lawrence went on to graduate school at Harvard and the Harvard Society of Fellows, where he studied with Menzel and developed his interest in stellar and nebular astronomy. After working in the War effort, he made his professorial debut at Indiana University, where he stayed until 1948 before leaving for the University of Michigan. Residing there for the next 14 years, he established his research reputation and helped develop the Michigan graduate program. In 1962, the opportunity arose to return to California, to UCLA, where he again was instrumental in founding a PhD program. There he stayed, through his retirement in 1984, doing research right up to the end. Eight other schools received him as visiting professor. Lawrence knew that to make inroads into astronomy, he needed to apply

  8. Obituary: Robert E. Fried, 1930-2003 (United States)

    Mannery, Edward J.; Szkody, Paula


    order to insure Braeside would continue to operate long after he could not be present, Bob and his wife, Marian, donated his observatory and adjacent home to the Arizona Sate University astronomy department for student use. In the last years of his life, he made sure everything worked for the students who used it in the early evening hours and then he continued on with his own research programs in the later half of the night and on weekends. His interest in students was not limited to those using his own telescope, although many visited and used his observatory from as far away as New York. Bob made an effort to work with students in other schools. He helped Flagstaff High School to build their own observatory on their grounds and worked with students from other states. Besides his night observing programs, Bob continued with his love and expertise in flying during the day. He donated his plane and time for volunteer mercy missions with Angel Flight and Flights for Life, flying patients to hospitals and medical supplies where they were needed. It was on one of these missions that Birdie went down about 40 miles north of Phoenix on November 13, 2003. The cause of the plane crash was not clear but the outcome was certain: the world had lost an admired, professional amateur astronomer and humanitarian. He is survived by his wife, Marian, his sister Louise, and his three daughters, Leslie, Sara and Amy, as well as stepchildren, grandchildren and many students he mentored. The stories told, and the pictures shown, at his Memorial at Lowell Observatory summarized a free-spirited and dedicated individual who lived life fully, joyfully and generously. His sense of humor, and spirited camaraderie will be missed as much as his observations.

  9. N-Acetylcarnosine sustained drug delivery eye drops to control the signs of ageless vision: Glare sensitivity, cataract amelioration and quality of vision currently available treatment for the challenging 50,000-patient population

    Directory of Open Access Journals (Sweden)

    Mark A Babizhayev


    Full Text Available Mark A Babizhayev1, Leslie Burke2, Philip Micans3, Stuart P Richer4,51Innovative Vision Products, Inc., County of New Castle, Delaware, USA; 2Wise Choice Products LLC, London, England, United Kingdom; 3IAS Group, Sark, United Kingdom; 4Eye Clinic DVA Medical Center, North Chicago, Illinois, USA; 5Department of Family and Preventive Medicine, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USABackground: Innovative Vision Products, Inc. (IVP’s scientists developed the lubricant eye drops (Can-C™ designed as 1% N-acetylcarnosine (NAC prodrug of L-carnosine containing a mucoadhesive cellulose-based compound combined with corneal absorption promoters in a sustained drug delivery system. Only the natural L-isomeric form of NAC raw material was specifically synthesized at the cGMP facility and employed for the manufacturing of Can-C™ eye drops.Objective and study design: In the present clinical study the authors assessed vision before and after 9 month term of topical ocular administration of NAC lubricant eye drops or placebo in 75 symptomatic patients with age-related uncomplicated cataracts in one or both eyes, with acuity in one eye of 20/40 or worse (best-corrected distance, and no previous cataract surgery in either eye and no other ocular abnormality and 72 noncataract subjects ranged in age from 54 to 78 years.Setting: Subjects in these subsample groups have reported complaints of glare and wanted to administer eye drops to get quick eye relief and quality of vision for their daily activities including driving and computer works. Following 9 months of treatment with NAC lubricant eye drops, most patients’ glare scores were improved or returned to normal in disability glare tests with Halometer DG. Improvement in disability glare was accompanied with independent improvement in acuity. Furthermore, patients with the poorest pretreatment vision were as likely to regain certain better visual function after 9

  10. Women in Chemistry: Their Changing Roles from Alchemical Times to the Mid-Twentieth Century (by Marelene Rayner-Canham and Geoffrey Rayner-Canham) (United States)

    Caserio, Marjorie C.


    authors are selective in their choice of biographies. They feature women on the basis of importance and interest rather than just the most notable. The crystallography chapter reveals the paradox that outstanding work is sometimes recognized (Lonsdale and Hodgkin) and sometimes not (Franklin). Chapter 6 is a fascinating account of the roller-coaster fortunes of women in radioactivity (Curie, Gleditsch, Chamie, Joliot-Curie, Perey, Brooks, Horovitz, Meitner, Noddack, and Goeppert-Mayer) and is the strongest chapter of the book. The biochemistry chapter acknowledges the work of Hoobler, Pennington, Denis, Fuller Brown, Cori, Elion, Willcock, Menten, Wrinch, and others. Industrial Chemistry was not a haven for women during the first part of this century, but the remarkable contributions of a few (Leslie, Wall, Blodgett, and Lathbury) are described in Chapter 8. The barriers for women in industry were numerous, including policy bans on married women and perceptions that women were unskilled or incapable of chemical work, even though they proved otherwise in the urgent need of wartime. Chapter 9 is a mixed bag, beginning with analytical chemists (Cremer and Miller), including surprisingly few who became prominent in education (Emma Perry Carr of Mount Holyoke and Mary Fieser of Bryn Mawr and Harvard), and ending with the famous historian of science Helen Metzger. In the concluding chapter, we are reminded of the ups and downs for women scientists in the first half of the 20th century. Blossoming educational and job opportunities led to record numbers of women in science by the early 1900s, but the numbers declined in the aftermath of World War I and to a lesser extent after World War II, as a result of changing societal attitudes when men and women compete for the same jobs. This thought-provoking book, elegantly written, concludes with the rhetorical question: will the current "second wave" of women scientists in this century be more permanent than the first, and will they

  11. Abundance estimation and conservation biology (United States)

    Nichols, J.D.; MacKenzie, D.I.


    should be focused on relationships between demographic processes such as survival and recruitment, the two quantities responsible for changes in abundance, rather than simply on the magnitudes of these quantities. They describe a type of Jolly–Seber capture–recapture model that permits inference about the underlying relationship between per capita recruitment rates and survival rates (Link & Barker, this volume). Implementation used Bayesian Markov Chain Monte Carlo methods and appeared to work well, yielding inferences about the relationship between recruitment and survival that were robust to selection of prior distribution. We believe that readers will find their arguments compelling, and we expect to see increased use of hierarchical modeling approaches in capture–recapture and related fields. Otto (presentation without paper) also recommended use of hierarchical models in analysis of multiple data sources dealing with population dynamics of North American mallards. He integrated survival inferences from ringing data, abundance information from aerial survey data, and recruitment information based on age ratios from a harvest survey. He used a Leslie matrix population projection model as an integrating framework and obtained estimates of breeding population size using all data.Otto’s approach also permitted inference about biases in estimated quantities. As with the work of Link & Barker (2004), we find Otto’s recommendation to use hierarchical models to integrate data from multiple sources to be very compelling. Alisauskas et al. (2004) report results of an analysis of capture–recapture data for a askatchewan population of white–winged scoters. They used the approach of Pradel (1996) to estimate population growth rate (See the PDF) directly. Estimates for 1975–1985 were quite low, but estimates for the recent period, 2000–2003,increased to values > 1. Parameter estimates for seniority, survival and per capita recruitment (Pradel, 1996) led to the

  12. The 15th Biannual National Congress of the South African Society of Psychiatrists, 10-14 August 2008, Fancourt, George, W Cape

    Directory of Open Access Journals (Sweden)

    Eugene Allers


    , Allison Breen, Allan J Flisher, Ritsuko Kakuma, Leslie Swartz, John Joska, Joanne Corrigall, Vikram Patel, MHaPP Research Programe Consortium 31. The cost of scaling up mental health care in low- and middle-income countries Crick Lund, Dan Chishlom, Shekhar Saxena 32. 'Tikking'Clock: The impact of a methamphetamine epidemic at a psychiatric hospital in the Western Cape P Milligan, J S Parker 33. Durban youth healh-sk behaviour: Prevalence f Violence-related behaviour D L Mkize 34. Profile of morality of patients amitted Weskoppies Psychiatric Hospital in Sout frican over a 5-Year period (2001-2005 N M Moola, N Khamker, J L Roos, P Rheeder 35. One flew over Psychiatry nest Leverne Mountany 36. The ethical relationship betwe psychiatrists and the pharmaceutical indutry Margaret  G Nair 37. Developing the frameor of a postgraduate da programme in mental health R J Nichol, B de Klerk, M M Nel, G van Zyl, J Hay 38. An unfolding story: The experience with HIV-ve patients at a Psychiatric Hospital J S Parker, P Milligan 39. Task shifting: A practical strategy for scalingup mental health care in developing countries Vikram Patel 40. Ethics: Informed consent and competency in the elderly Willie Pienaar 41. Confronting ommonmoral dilemmas. Celebrating uncertainty, while in search  patient good Willie Pienaar 42. Moral dilemmas in the treatment and repatriation of patients with psychtorders while visiting our country Duncan Ian Rodseth 43. Geriatrics workshop (Psegal symposium: Medico-legal issuess in geriatric psyhiatry Felix Potocnik 44. Brain stimulation techniques - update on recent research P J Pretorius 45. Holistic/Alternative treatments in psychiatry T Rangaka, J Dill 46. Cognitive behaviour therapy and other brief interventions for management of substances Solomon Rataemane 47. A Transtheoretical view of change Nathan P Rogerson 48. Profile of security breaches in longerm mental health care users at Weskoppies Hospital over a 6-month period Deleyn Rema, Lindiwe Mthethwa

  13. Abundance estimation and Conservation Biology

    Directory of Open Access Journals (Sweden)

    Nichols, J. D.


    our attention should be focused on relationships between demographic processes such as survival and recruitment, the two quantities responsible for changes in abundance, rather than simply on the magnitudes of these quantities. They describe a type of Jolly–Seber capture–recapture model that permits inference about the underlying relationship between per capita recruitment rates and survival rates (Link & Barker, this volume. Implementation used Bayesian Markov Chain Monte Carlo methods and appeared to work well, yielding inferences about the relationship between recruitment and survival that were robust to selection of prior distribution. We believe that readers will find their arguments compelling, and we expect to see increased use of hierarchical modeling approaches in capture–recapture and related fields. Otto (presentation without paper also recommended use of hierarchical models in analysis of multiple data sources dealing with population dynamics of North American mallards. He integrated survival inferences from ringing data, abundance information from aerial survey data, and recruitment information based on age ratios from a harvest survey. He used a Leslie matrix population projection model as an integrating framework and obtained estimates of breeding population size using all data.Otto’s approach also permitted inference about biases in estimated quantities. As with the work of Link & Barker (2004, we find Otto’s recommendation to use hierarchical models to integrate data from multiple sources to be very compelling. Alisauskas et al. (2004 report results of an analysis of capture–recapture data for a askatchewan population of white–winged scoters. They used the approach of Pradel (1996 to estimate population growth rate (See the PDF directly. Estimates for 1975–1985 were quite low, but estimates for the recent period, 2000–2003,increased to values > 1. Parameter estimates for seniority, survival and per capita recruitment (Pradel, 1996

  14. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2006-12-01 VILAdli Bilimler Sempozyumu Çocuk İstismarı ve İhmaline Güncel Yaklaşımlar 24-27 Mayıs 2007, Gaziantep İletişim: Dr.Aysun BARANSEL ISIR Gaziantep Üniversitesi Tıp Fakültesi Adli Tıp A.D. Tel: 0 342 360 60 60 /76181 E-posta: Web: Examination of Tire Impression and tire Track Evidence Course 7-11 May To be held at the Ramada Inn in Jacksonville, FL. CONTACT: William J. Bodziak 38 Sabal Bend Palm Coast, FL 32137 (386 447-3567 Fax: (386 447-3568 Basic Facial Reconstruction Sculpture Workshop 7-11 May To be held at Scottsdale Artists School in Scottsdale, AZ. CONTACT: Betty Pat. Gatliff SKULLpture Lab 1026 Leslie Lane Norman, OK 73069-4501 (405 321-8706 Prosecutors' Conference 14-16 May To be held at the Tides Inn in Irvington, VA. Martha M. Allen Program Support Coordinator The Virginia Institute of Forensic Science and Medicine ENFSI Annual Meeting 2007 May 30 - June 02, 2007 Riga, Latvia Further information: Web: The 2007 Techno Security Conference 3-6 June2007, USA Further information: Myrtle Beach, South Carolina Tel: (843 8280828 Web: 8th International Interlock Symposium (IIS. International Council on Alcohol, Drugs, and Traffic Safety (ICADTS, The International Association of Forensic Toxicologists (TIAFT 26-30 August 2007,Seattle, USA Further information: E-mail:T2007@wsp. Web: http :// Modern Developments in Handwriting Examination 20-22 September 2007, Vilnius, Lithuania Further information: E-mail: Tel: +37052638574 Web: Modern Developments in Handwriting Examination 20-22, September 2007 VILNIUS, LITHUANIA or call +37052638574 Metropolitan Laboratory Conference Centre Trace and Transfer 7 September 2007 One Day Conference Convenors: Callum Sutherland and Anna-Marie O’Connor

  15. Obituary: Janet Akyüz Mattei, 1943-2004 (United States)

    Williams, Thomas R.; Willson, Lee Anne


    in Belgium for AAVSO to hold its first European meeting in Brussels in July 1990. The meeting proved a huge success, and was followed in 1997 by a second AAVSO European meeting in Sion, Switzerland and a Pan-Pacific meeting in 2003 in Hawaii. Through Janet's leadership, AAVSO reached out to the observers who were already supporting the association with their observations. One of Janet's strong interests was in education. Using a grant from the National Science Foundation, she led efforts to create Hands-On Astrophysics (HOA) based largely on variable stars and AAVSO data. Though it took several years to develop, HOA became the basis for a number of popular teacher workshops and is sure to lead many high school students into careers in science. Janet also helped many future professionals in astronomy, including Karen Meech and Peter Garnavich, and a few in other areas, by providing opportunities for them to work at headquarters during their studies or during an intermission in their formal schooling. Janet was active in, and honored by, other professional and amateur organizations. A member of the American Astronomical Society (AAS), she received the AAS's George van Biesbroeck award in 1993, served on the AAS Annenberg Award Committee (1994-1997) and served as the first chair of the AAS Professional Amateur Cooperation Committee. Also in 1993, the Astronomical League with their Leslie Peltier Award honored Janet for her leadership of the AAVSO and contributions to variable star astronomy. Janet was elected a director of the Astronomical Society of the Pacific (ASP) and served six years in that capacity (1994-2000), co-chairing at least one Pro-Am workshop with the ASP. She was a member of three IAU Commissions over her thirty-five years of membership in that organization. In 1995, Janet was honored by the award of the Royal Astronomical Society's Jackson-Gwilt Medal and was the first recipient of the Giovanni Battista Lacchini Award for collaboration with amateur

  16. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD


    Full Text Available 57th American Academy of Forensic Science Annual Meeting February 21-26 2005. New Orleans, Louisiana, TX, USA. Further Information: Nancy J. Jackson, Director of Administration AAFS, P.O. Box 669, Colorado Springs, CO 80901-0669, USA. Phone: 1-719-6361100; Fax:1-719-6361993 94th Annual Meeting United States and Canadian Academy of Pathology February 26-March 4, 2005. San Antonio, TX, USA Further information: United States andCanadianAcademy of Pathology, 3643WaltonWay Extension, Augusta, GA30909, USA. Phone: 1-706-7337550; Fax: 1-706-7338033 E-mail:; 45th Conference on Legal Medicine March 4-6 2005. San Diego, CA, USA. Further information: Sue O'Sullivan, American College of Legal Medicine, 1111 N. Plaza Drive, Suite 550, Schaumburg, IL 60173. Phone: (847 969-0283, Fax: (847 517-7229, E-mail:, Basic Facial Reconstruction Sculpture Workshop March 11-13 2005 San Antonio, TX, USA. To be held at the UTHSCSA Dental School in San Antonio, TX. Further information: Betty Pat. Gatliff, SKULLpture Lab, 1026 Leslie Lane, Norman, OK 73069. Phone: (405 321-8706. Academy of Criminal Justice Sciences meeting March 14-19 2005 Chicago, Illinois, USA Further information: 42nd Annual Meeting Academy of Criminal Justice March 17-19 2005 Chicago, IL, USA Sciences Further information: Laura Monaco, Academy of Criminal Justice Sciences, 7319 Hanover Parkway, Suite C, Greenbelt, MA 20770, USA. Phone: 1-301-4466300; Fax: 1-301-4462819; E-mail:; The Sixth International Conference on Forensic Statistics March 17-19 2005 Tempe, A2, USA. Further information: Andrew (Sandy Askland, PhD, Center for Law, Science, & Technology, Arizona State University, College of Law, McAllister & Orange Streets, PO Box 877906, Tempe, A2 85287-7906. Phone: (480 965- 6606; Fax: (480 965-2427, E-mail: sandy.askland@, 41st Annual Forensic Dental

  17. 16th National Congress of the South African Society of Psychiatrists (SASOP

    Directory of Open Access Journals (Sweden)

    Christer Allgulander


    of start Sean Kaliski 21. Psychiatric disorders abd psychosocial correlates of high HIV risk sexual behaviour in war-effected Eatern Uganda E Kinyada, H A Weiss, M Mungherera, P Onyango Mangen, E Ngabirano, R Kajungu, J Kagugube, W Muhwezi, J Muron, V Patel 22. One year of Forensic Psychiatric assessment in the Northern Cape: A comparison with an established assessment service in the Eastern Cape N K Kirimi, C Visser 23. Mental Health service user priorities for service delivery in South Africa Sharon Kleintjes, Crick Lund, Leslie Swartz, Alan Flisher and MHaPP Research Programme Consortium 24. The nature and extent of over-the-counter and prescription drug abuse in cape town Liezl Kramer 25. Physical health issues in long-term psychiatric inpatients: An audit of nursing statistics and clinical files at Weskoppies Hospital Christa Kruger 26. Suicide risk in Schizophrenia - 20 Years later, a cohort study Gian Lippi, Ean Smit, Joyce Jordaan, Louw Roos 27.Developing mental health information systems in South Africa: Lessons from pilot projects in Northern Cape and KwaZulu-Natal Crick Lund, S Skeen, N Mapena, C Isaacs, T Mirozev and the Mental Health and Poverty Research Programme Consortium Institution 28. Mental health aspects of South African emigration Maria Marchetti-Mercer 29. What services SADAG can offer your patients Elizabeth Matare 30. Culture and language in psychiatry Dan Mkize 31. Latest psychotic episode Povl Munk-Jorgensen 32. The Forensic profile of female offenders Mo Nagdee, Helmut Fletcher 33. The intra-personal emotional impact of practising psychiatry Margaret Nair 34. Highly sensitive persons (HSPs and implications for treatment Margaret Nair 35. Task shifting in mental health - The Kenyan experience David M Ndetei 36. Bridging the gap between traditional healers and mental health in todya's modern psychiatry David M Ndetei 37. Integrating to achieve modern psychiatry David M Ndetei 38. Non-medical prescribing: Outcomes from a pharmacist-led post

  18. AAS 227: Day 4 (United States)

    Kohler, Susanna


    mean its not typical. While we wait for more and better observations of exoplanet systems, theory can help us understand why the Solar System formed the way it did, and where to look for systems that formed the same way. For example, some of Murray-Clays previous work has shown that metal-rich stars tend to host more hot Jupiters and eccentric giant planets (very different from Solar System architecture). So if we want to find more systems like our own, we need to search around stars with low-to-moderate metallicity.Extrasolar Planets: Hosts, Interactions, Formation, and Interiors (by Caroline Morley)This session was a mashup of a variety of planetary topics ranging from solar flares to interiors to habitability.Leslie Rogers kicked off the session by presenting work done in collaboration with her student Ellen Price to constrain the composition of the ultra-short period (4 hours!?!) planet candidate KOI 1843.03 using models of the objects interior. Since its so close to the star, it can only exist without being torn apart if its very dense, which allows them to calculate that it must be iron-rich like Mercury!Next Kevin Thielen, an undergrad at Eckerd College, presented results from a summer project to apply a variable polytrope index to planet models. Tom Barclay then showed models that demonstrate the huge effect that having giant planets in the outer solar system has on the formation of terrestrial planets. He finds that without Jupiter and Saturn, more planets would form (8 instead of 3-4!) and giant impacts (like the moon-forming impact) would be more frequent but less energetic.Aomawa Shields shifted to discuss her 3D GCM models to determine the orbital configurations that would lead to liquid water on the surface of the planet Kepler-62f. She determines the effect of eccentricity, axis tilt (obliquity), and rotation rate on habitability. Edward Guinan brought us closer to home discussing the potential for superflares solar flares up to hundreds of times more

  19. From Editor vol 11, No.4

    Directory of Open Access Journals (Sweden)

    Ugur Demiray


    determine the characteristics in effective and successful online and/or face-to-face instructors. Survey information was divided into five categories and provided very different information. Although this was a limited study, it provided valuable information that instructors cannot view teaching both online and face to face classes as one-fits all type approach. Two books and a conference are reviewed in this issue. The first book was about Learning And Instructional Technologies For The 21st Century Leslie Moller, Jason Bond Huett and Douglas M. Harvey (Eds. and reviewed by Reviewed by Reviewed by Alev ATES, Ege University, Izmir, TURKEY. She summarized that the book helps closing a gap in the instructional technology research for the 21st century with many implications from case studies and experimental studies with students and teachers. A Conference o n An International Symposium On The New Vista Education System Of Open, Distance And E-Learning is reviewed by A. Q. M. Bazlur RASHID, Bangladesh Agricultural University, BANGLADESH International Symposium on Open, Distance and E-Learning held at Discovery Kartika Plaza Hotel at Bali, Indonesia by hosted by ICT Centre for Education, Ministry of National Education of the Republic Indonesia was a unique forum for scientific expositions on the progress of development and implementation on the fast-growing ICT global network, especially in the field of open, distance and e-learning. The second book is about “Educational Technology In Practice Research and Practical Case Studies from the Field” edited by Edited by Wanjira KINUTHIA and Steward MARSHALL and reviewed by Ozden SAHIN-IZMIRLI, Computer Education and Instructional Technology, Eskisehir Osmangazi University, Eskisehir, TURKEY. The editors stated that when technological tools are used to establish an effective and productive study process in education, the concept of learning technology is used instead of educational technology. The editors of the book considers the

  20. Editorial

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    Ugur Demiray


    Utilization of Weblog And Podcast Technology in A Teacher Education Department” sent by Leslie STURDIVANT ENNIS, J. D. And Elizabeth Anne GAMBRELL from Samford University Birmingham, Alabama USA. The main objective of the study is to compare the utilization of weblog and podcast technology by undergraduate university faculty and Millennial college students. This study is conducted to test the hypothesis, formed from existing literature, that there might be a difference in the utilization of weblog and podcast technology between faculty and Millennial students in a Teacher Education Department. One hundred surveys were utilized based upon the number of students currently enrolled in Teacher Education classes at the time of the study. Fifty-nine students and five undergraduate faculties participated in the survey. The study refuted the hypothesis that there is a difference in weblog and podcast utilization between faculty and Millennial students. There was no significant difference in the utilization of weblogs and podcasts in the two populations. The results indicate that the perceived technological gap between Millennial students and university faculty is not as prevalent as theorized by the existing literature.The eight article is again came from Bangladesh, Presidency University. Titled article is on Professional Development of Higher Education Teachers: Can ODL Contribute?, written by Md. Jamal HOSSAIN. This paper, considering Levis’ (2002 opinion about the necessity of e-learning, Goodson’s (2000 principles of teacher professionalism, Nordkvelle’s (2006 view on the challenge of ODL-organization, Boshier’s (1971 Education Participation Scale (EPS, and Houle’s (1961 philosophy of six classic needs of a practicing professional, tries to find out the role of ODL in the professional development of higher education teachers in Bangladesh on the basis of a study. The related survey involves a sample of more than 100 teachers from a number of ten private and public

  1. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Other”

    Directory of Open Access Journals (Sweden)

    Various Authors