Sample records for lens wobble artifacts

  1. Milankovitch wobble? (United States)

    Mitchell, R. N.; Thissen, C.; Kirschvink, J. L.; Schrag, D. P.; Montanari, A.; Coccioni, R.; Slotznick, S. P.; Yamazaki, T.; Penserini, B. D.; Abrahams, J. N. H.; Cruz-Heredia, M.; Evans, D. A.


    High-resolution paleomagnetism of Cretaceous-aged limestone in Italy reveals evidence for a previously unrecognized ~10˚ directional variation, or "wobble", of either the geographic or magnetic pole on a 106-year, "Milankovitch" time scale. Ten ~1 million year (Myr) wobbles of magnetic inclination can be identified and correlated across Italy from 87-74 Myr ago, potentially refining the global polarity time scale and seafloor spreading rates. Milankovitch wobble is an omnipresent geophysical process that represents, irrespective of its mechanism, a new chronometer for age calibration with paleomagnetism. If Milankovitch wobble is interpreted as a geomagnetic artifact—the long-considered but still unproven idea that astronomical variations influence the geodynamo—the geocentric-axial dipole hypothesis would only be viable when averaged over time scales 100 times greater than currently thought, making present-day geocentricity largely coincidental. If interpreted as true geographic change, Milankovitch wobble implies an unrecognized, rapid time scale (~10˚ Myr-1) of true polar wander, possibly due to ice sheet dynamics driven by the 1.2 Myr modulation of Earth's rotational obliquity. Stable isotope data co-vary with the Milankovitch wobble, possibly favoring the polar wander mechanism that predicts rapid environmental change where the geomagnetic artifact hypothesis does not.

  2. Chandler wobbles and the geomagnetic field (United States)

    Flodmark, Stig; Davstad, K.


    Paleomagnetic motion of the magnetic pole is explained by angular momentum balance between the magnetic field, inner core, outer core, and mantle. The Chandler wobbles are explained as a nutation of the mantle and crust, caused by transfer of angular momentum between the core and mantle. Evidence is found for the atmosphere not to be fully responsible for the annual oscillation period of the Chandler wobbles. The main reasons for the principal periods of 12 and 14 months are found to be the flattenings of mantle and core, respectively. The fluid core rotates collectively, as a consequence of globally coworking long-distance electromagnetic coupling. Short-distance forces may locally displace fluid core material without essentially deforming its ellipsoid of inertia. The longitudinal polar drifts of the mantle and outer core are also explained by core-mantle interaction. The core is found to force the Chandler period on the mantle, and it has high wobbling energy in comparison with the mantle.

  3. On the wobble GoU and related pairs.


    Masquida, B; Westhof, E


    The wobble GoU pairs have been implicated in several biological processes where RNA molecules play a key role. We review the geometrical and conformational properties of wobble GoU pairs on the basis of available crystal structures of RNAs at high resolution. The similarities with the wobble A+oC pairs and UoU pairs are illustrated, while the differences with the recently discovered bifurcated G x U pairs are contrasted.

  4. Tilted-axis wobbling in odd-mass nuclei (United States)

    Budaca, R.


    A triaxial rotor Hamiltonian with a rigidly aligned high-j quasiparticle is treated by a time-dependent variational principle, using angular momentum coherent states. The resulting classical energy function has three unique critical points in a space of generalized conjugate coordinates, which can minimize the energy for specific ordering of the inertial parameters and a fixed angular momentum state. Because of the symmetry of the problem, there are only two unique solutions, corresponding to wobbling motion around a principal axis and, respectively, a tilted axis. The wobbling frequencies are obtained after a quantization procedure and then used to calculate E 2 and M 1 transition probabilities. The analytical results are employed in the study of the wobbling excitations of 135Pr nucleus, which is found to undergo a transition from low angular momentum transverse wobbling around a principal axis toward a tilted-axis wobbling at higher angular momentum.

  5. Electrocardiographic gating of list mode data with a positron emission tomography system that utilizes wobbling motion to achieve uniform sampling

    International Nuclear Information System (INIS)

    Gaeta, J.M.; Yerian, K.A.; Mullani, N.A.


    An interactive software package has been developed for gating of list mode data acquired with PET. The package supports: histogram displays (ie. for determining an acceptable beat interval length window), automatic rejection of beats outside the window, forward or backward gating capabilities, capability of specifying the position of the gating interval, and of the time interval within the list mode study to be reformatted. The interaction of PET wobble motion frequency and heart beat frequency may result in image non-uniformities (ringing artifacts), due to incomplete wobble sampling. Therefore, the reconstruction software incorporates a very simple scheme for correcting for the amount of time spent at each wobble position and allowing for the decay of short lived isotopes such as Rubidium-82 (Rb-82). Rb-82 myocardial uptake images free of non-uniformity artifacts and quantitatively accurate have been reconstructed for 10 different dog studies, and 8 patient studies. Multi-slice frames at discrete portions of the heart cycle (i.e. End Diastole) and multi-gated sequences for cine display have been produced

  6. The Pathology of Wobbly Hedgehog Syndrome. (United States)

    Díaz-Delgado, Josué; Whitley, Derick B; Storts, Ralph W; Heatley, Jill J; Hoppes, Sharman; Porter, Brian F


    Wobbly hedgehog syndrome (WHS) is a leading cause of neurologic disease in African pygmy hedgehogs (APHs; Atelerix albiventris). This study describes the signalment, clinical signs, gross, microscopic, and ultrastructural lesions of WHS in a cohort of 12 pet APHs. Microscopically, lesions consisted of status spongiosus of the white matter, typically bilateral and symmetrical, with myelin degeneration and loss that was accompanied by neuronal/axonal degeneration plus reactive microgliosis and mild, focal astrocytosis and astrogliosis. Lesions were most severe in the cerebellum and medulla oblongata, as well as cervical and thoracic spinal cord. Less affected areas were the corona radiata, corpus callosum, corpus striatum, internal capsule, and the mesencephalon. Ultrastructurally, the lesions consisted of splitting of the myelin sheath at the intraperiod line with subsequent focal expansion, resulting in status spongiosus, disruption, dilatation, rhexis, and phagocytosis. Based on these results, WHS is best described as a "spongy myelinopathy" with widespread central nervous system involvement.

  7. Base-pairing versatility determines wobble sites in tRNA anticodons of vertebrate mitogenomes.

    Directory of Open Access Journals (Sweden)

    Miguel M Fonseca

    Full Text Available BACKGROUND: Vertebrate mitochondrial genomes typically have one transfer RNA (tRNA for each synonymous codon family. This limited anticodon repertoire implies that each tRNA anticodon needs to wobble (establish a non-Watson-Crick base pairing between two nucleotides in RNA molecules to recognize one or more synonymous codons. Different hypotheses have been proposed to explain the factors that determine the nucleotide composition of wobble sites in vertebrate mitochondrial tRNA anticodons. Until now, the two major postulates--the "codon-anticodon adaptation hypothesis" and the "wobble versatility hypothesis"--have not been formally tested in vertebrate mitochondria because both make the same predictions regarding the composition of anticodon wobble sites. The same is true for the more recent "wobble cost hypothesis". PRINCIPAL FINDINGS: In this study we have analyzed the occurrence of synonymous codons and tRNA anticodon wobble sites in 1553 complete vertebrate mitochondrial genomes, focusing on three fish species with mtDNA codon usage bias reversal (L-strand is GT-rich. These mitogenomes constitute an excellent opportunity to study the evolution of the wobble nucleotide composition of tRNA anticodons because due to the reversal the predictions for the anticodon wobble sites differ between the existing hypotheses. We observed that none of the wobble sites of tRNA anticodons in these unusual mitochondrial genomes coevolved to match the new overall codon usage bias, suggesting that nucleotides at the wobble sites of tRNA anticodons in vertebrate mitochondrial genomes are determined by wobble versatility. CONCLUSIONS/SIGNIFICANCE: Our results suggest that, at wobble sites of tRNA anticodons in vertebrate mitogenomes, selection favors the most versatile nucleotide in terms of wobble base-pairing stability and that wobble site composition is not influenced by codon usage. These results are in agreement with the "wobble versatility hypothesis".

  8. A cycloidal wobble motor driven by shape memory alloy wires (United States)

    Hwang, Donghyun; Higuchi, Toshiro


    A cycloidal wobble motor driven by shape memory alloy (SMA) wires is proposed. In realizing a motor driving mechanism well known as a type of reduction system, a cycloidal gear mechanism is utilized. It facilitates the achievement of bidirectional continuous rotation with high-torque capability, based on its high efficiency and high reduction ratio. The applied driving mechanism consists of a pin/roller based annular gear as a wobbler, a cycloidal disc as a rotor, and crankshafts to guide the eccentric wobbling motion. The wobbling motion of the annular gear is generated by sequential activation of radially phase-symmetrically placed SMA wires. Consequently the cycloidal disc is rotated by rolling contact based cycloidal gearing between the wobbler and the rotor. In designing the proposed motor, thermomechanical characterization of an SMA wire biased by extension springs is experimentally performed. Then, a simplified geometric model for the motor is devised to conduct theoretical assessment of design parametric effects on structural features and working performance. With consideration of the results from parametric analysis, a functional prototype three-phase motor is fabricated to carry out experimental verification of working performance. The observed experimental results including output torque, rotational speed, bidirectional positioning characteristic, etc obviously demonstrate the practical applicability and potentiality of the wobble motor.

  9. Aquatic bacteria elongate and wobble their bodies for flagellar performance (United States)

    Liu, Bin; Valenzuela, Joanna; Chopra, Pooja


    Bacteria are endowed with well-regulated sizes and shapes. A bacillus has a rod-like cell body, achieving swimming motility by rotating a single flagellum or multiple flagella. Along with other shapes, this elongated cell is often viewed as a payload, and its movements are regarded as passive responses to its flagellar propulsion. Here, we simultaneously measured the morphology and movement of individual free-swimming bacteria using an automated tracking microscope and 3D reconstruction techniques. These cells were found to consistently precess, based on reconstructions of the apparent wobbling movements viewed from a microscope. Through a hydrodynamic model that incorporates such precessing cell bodies and rod-like geometries, we found that there is a critical cell size below which wobbling movement is beneficial for flagellar performance. This critical cell size is consistent with the cellular morphologies of Caulobacter crescentus and Escherichia coli, as examples of single- and multi-flagellated species that are known for wobbling movements in aquatic environments. We also showed that the moderate cell sizes of these species could be attributed to a compromise between dispersal speed and power consumption. The authors thank the support of NSF-CREST: Center for Cellular and Biomolecular Machines at UC Merced (NSF-HRD-1547848).

  10. Foot force models of crowd dynamics on a wobbly bridge. (United States)

    Belykh, Igor; Jeter, Russell; Belykh, Vladimir


    Modern pedestrian and suspension bridges are designed using industry standard packages, yet disastrous resonant vibrations are observed, necessitating multimillion dollar repairs. Recent examples include pedestrian-induced vibrations during the opening of the Solférino Bridge in Paris in 1999 and the increased bouncing of the Squibb Park Bridge in Brooklyn in 2014. The most prominent example of an unstable lively bridge is the London Millennium Bridge, which started wobbling as a result of pedestrian-bridge interactions. Pedestrian phase locking due to footstep phase adjustment is suspected to be the main cause of its large lateral vibrations; however, its role in the initiation of wobbling was debated. We develop foot force models of pedestrians' response to bridge motion and detailed, yet analytically tractable, models of crowd phase locking. We use biomechanically inspired models of crowd lateral movement to investigate to what degree pedestrian synchrony must be present for a bridge to wobble significantly and what is a critical crowd size. Our results can be used as a safety guideline for designing pedestrian bridges or limiting the maximum occupancy of an existing bridge. The pedestrian models can be used as "crash test dummies" when numerically probing a specific bridge design. This is particularly important because the U.S. code for designing pedestrian bridges does not contain explicit guidelines that account for the collective pedestrian behavior.

  11. Artifacts in digital radiography

    International Nuclear Information System (INIS)

    Min, Jung Whan; Kim, Jung Min; Jeong, Hoi Woun


    Digital Radiography is a big part of diagnostic radiology. Because uncorrected digital radiography image supported false effect of Patient’s health care. We must be manage the correct digital radiography image. Thus, the artifact images can have effect to make a wrong diagnosis. We report types of occurrence by analyzing the artifacts that occurs in digital radiography system. We had collected the artifacts occurred in digital radiography system of general hospital from 2007 to 2014. The collected data had analyzed and then had categorize as the occurred causes. The artifacts could be categorized by hardware artifacts, software artifacts, operating errors, system artifacts, and others. Hardware artifact from a Ghost artifact that is caused by lag effect occurred most frequently. The others cases are the artifacts caused by RF noise and foreign body in equipments. Software artifacts are many different types of reasons. The uncorrected processing artifacts and the image processing error artifacts occurred most frequently. Exposure data recognize (EDR) error artifacts, the processing error of commissural line, and etc., the software artifacts were caused by various reasons. Operating artifacts were caused when the user did not have the full understanding of the digital medical image system. System artifacts had appeared the error due to DICOM header information and the compression algorithm. The obvious artifacts should be re-examined, and it could result in increasing the exposure dose of the patient. The unclear artifact leads to a wrong diagnosis and added examination. The ability to correctly determine artifact are required. We have to reduce the artifact occurrences by understanding its characteristic and providing sustainable education as well as the maintenance of the equipments

  12. Artifacts in digital radiography

    Energy Technology Data Exchange (ETDEWEB)

    Min, Jung Whan [Dept. of Radiological Technology, Shin Gu University, Sungnam (Korea, Republic of); Kim, Jung Min [Dept. of Radiological Technology, Korea University, Seoul (Korea, Republic of); Jeong, Hoi Woun [Dept. of Radiological Technology, Beakseok Culture University, Cheonan (Korea, Republic of)


    Digital Radiography is a big part of diagnostic radiology. Because uncorrected digital radiography image supported false effect of Patient’s health care. We must be manage the correct digital radiography image. Thus, the artifact images can have effect to make a wrong diagnosis. We report types of occurrence by analyzing the artifacts that occurs in digital radiography system. We had collected the artifacts occurred in digital radiography system of general hospital from 2007 to 2014. The collected data had analyzed and then had categorize as the occurred causes. The artifacts could be categorized by hardware artifacts, software artifacts, operating errors, system artifacts, and others. Hardware artifact from a Ghost artifact that is caused by lag effect occurred most frequently. The others cases are the artifacts caused by RF noise and foreign body in equipments. Software artifacts are many different types of reasons. The uncorrected processing artifacts and the image processing error artifacts occurred most frequently. Exposure data recognize (EDR) error artifacts, the processing error of commissural line, and etc., the software artifacts were caused by various reasons. Operating artifacts were caused when the user did not have the full understanding of the digital medical image system. System artifacts had appeared the error due to DICOM header information and the compression algorithm. The obvious artifacts should be re-examined, and it could result in increasing the exposure dose of the patient. The unclear artifact leads to a wrong diagnosis and added examination. The ability to correctly determine artifact are required. We have to reduce the artifact occurrences by understanding its characteristic and providing sustainable education as well as the maintenance of the equipments.

  13. Dynamics in artifact ecologies

    DEFF Research Database (Denmark)

    Bødker, Susanne; Klokmose, Clemens Nylandsted


    artifacts influence the use of others. Understanding this interplay becomes more and more essential for interaction design as our artifact ecologies grow. This paper continues a recent discourse on artifact ecologies. Through interviews with iPhone users, we demonstrate that relationships between artifacts...

  14. Mesoscale hybrid calibration artifact (United States)

    Tran, Hy D.; Claudet, Andre A.; Oliver, Andrew D.


    A mesoscale calibration artifact, also called a hybrid artifact, suitable for hybrid dimensional measurement and the method for make the artifact. The hybrid artifact has structural characteristics that make it suitable for dimensional measurement in both vision-based systems and touch-probe-based systems. The hybrid artifact employs the intersection of bulk-micromachined planes to fabricate edges that are sharp to the nanometer level and intersecting planes with crystal-lattice-defined angles.

  15. An electrostatic lower stator axial-gap polysilicon wobble motor part II: Fabrication and performance

    NARCIS (Netherlands)

    Legtenberg, R.; Legtenberg, Rob; Berenschot, Johan W.; van Baar, J.J.J.; Elwenspoek, Michael Curt

    This paper presents the fabrication and first performance characteristics of electrostatically driven axial-gap polysilicon wobble motors. The fabrication is based on a four mask process using polysilicon surface-micromachining techniques. Three twelve-stator-pole wobble motor designs have been

  16. tRNA's wobble decoding of the genome: 40 years of modification. (United States)

    Agris, Paul F; Vendeix, Franck A P; Graham, William D


    The genetic code is degenerate, in that 20 amino acids are encoded by 61 triplet codes. In 1966, Francis Crick hypothesized that the cell's limited number of tRNAs decoded the genome by recognizing more than one codon. The ambiguity of that recognition resided in the third base-pair, giving rise to the Wobble Hypothesis. Post-transcriptional modifications at tRNA's wobble position 34, especially modifications of uridine 34, enable wobble to occur. The Modified Wobble Hypothesis proposed in 1991 that specific modifications of a tRNA wobble nucleoside shape the anticodon architecture in such a manner that interactions were restricted to the complementary base plus a single wobble pairing for amino acids with twofold degenerate codons. However, chemically different modifications at position 34 would expand the ability of a tRNA to read three or even four of the fourfold degenerate codons. One foundation of Crick's Wobble Hypothesis was that a near-constant geometry of canonical base-pairing be maintained in forming all three base-pairs between the tRNA anticodon and mRNA codon on the ribosome. In accepting an aminoacyl-tRNA, the ribosome requires maintenance of a specific geometry for the anticodon-codon base-pairing. However, it is the post-transcriptional modifications at tRNA wobble position 34 and purine 37, 3'-adjacent to the anticodon, that pre-structure the anticodon domain to ensure the correct codon binding. The modifications create both the architecture and the stability needed for decoding through restraints on anticodon stereochemistry and conformational space, and through selective hydrogen bonding. A physicochemical understanding of modified nucleoside contributions to the tRNA anticodon domain architecture and its decoding of the genome has advanced RNA world evolutionary theory, the principles of RNA chemistry, and the application of this knowledge to the introduction of new amino acids to proteins.

  17. Small Artifacts - Big Technologies

    DEFF Research Database (Denmark)

    Kreiner, Kristian


    The computer IC is the heart of the information and telecommunication technology. It is a tiny artifact, but with incredible organizing powers. We use this physical artifact as the location for studying central problems of the knowledge economy. First, the paper describes the history of chip design...

  18. Chandler wobble excitation by catastrophic flooding of the Black Sea

    Directory of Open Access Journals (Sweden)

    E. Boschi


    Full Text Available It is now widely accepted that during the late Quaternary glaciation the Black Sea formed an isolated inland lake (Ross et al., 1970. New geological data and the recognition of sudden population movements away from the Black Sea coasts suggest that the basin was rapidly flooded through the Bosphorus sill 7150 years bp, causing a sea level rise of ~ 135 m in a few years (Ryan et al., 1997. As shown here, such a catastrophic redistribution of mass has significantly altered the amplitude of the Chandler wobble, the free motion of the pole of rotation around the main inertia axis of the Earth (Lambeck, 1980. We also estimate that during the flooding the pole of rotation was diverted from its secular path and shifted by ~ 30 m, at a rate of several meters per year. These rotational variations are found to be orders of magnitude larger than those produced by other short-term geophysical processes, such as earthquakes seismic moment release (O'Connell and Dziewonski, 1979; Chao et al.,1996, anthropogenic water impoundment (Chao, 1995, and tectonic mass movements (Alfonsi and Spada, 1998. The Black Sea flooding may thus be responsible for the most drastic change in the rotational parameters of the Earth in the recent history of our planet.

  19. Obscuring the ancient artifacts

    International Nuclear Information System (INIS)

    Tugrul, B.


    Radiography is a non-destructive method which is preferable for ancient artifacts. X-rays, gama rays, beta rays and neutrons can be used for radiography. Differences of them and application materials can be different. In this study, the radiographic techniques are determined with application parameters according to materials of the artifacts, and some interesting examples are given. Therefore, investigation of the artifacts can be realized for definition of physical properties, manufacturing techniques and quality controls of them easily by the application of the radiography. (author)

  20. Wobbling excitations in odd-A nuclei with high-j aligned particles

    International Nuclear Information System (INIS)

    Hamamoto, Ikuko


    Using the particle-rotor model in which one high-j quasiparticle is coupled to the core of triaxial shape, wobbling excitations are studied. The family of wobbling phonon excitations can be characterized by: (a) very similar intrinsic structure while collective rotation shows the wobbling feature; (b) strong B(E2;I→I-1) values for Δn w =1 transitions where n w expresses the number of wobbling phonons. For the Fermi level lying below the high-j shell with the most favorable triaxiality γ≅+20 deg., the wobbling phonon excitations may be more easily identified close to the yrast line, compared with the Fermi level lying around the middle of the shell with γ≅-30 deg. The spectroscopic study of the yrast states for the triaxial shape with -60 deg. <γ<0 are illustrated by taking a representative example with γ=-30 deg., in which a quantum number related with the special symmetry is introduced to help the physics understanding

  1. Effects of wobble board training on weight distribution on the lower extremities of sedentary subjects. (United States)

    Adedoyin, Rufus A; Olaogun, Matthew O B; Omotayo, Kehinde; Olawale, Olajide A; Egwu, Michael O


    Inequality of weight distribution on the lower extremities affects the posture and gait performance of an individual. The effect of wobble board training on weight distribution on the lower extremities is presently unknown. The purpose of this study was to investigate the effects of a six week wobble board exercise training program on the weight distribution in the lower extremities. Subjects (n = 16) in the wobble board group were trained three times a week for the period of six weeks. The subjects in the control group (n = 13) did not receive any training. Weight distribution symmetry scores improved by 9% and 2% in the wobble board and control groups, respectively, no significant difference was found between the two groups' pre-training weight distribution on the lower extremities. The two-ways repeated analysis of variance revealed a significant F ratio between the two groups (P board group, while no significant improvement was recorded within the control group. Our findings implied that the wobble board exercise program could be used to improve the symmetry of weight distribution on the lower extremities in sedentary subjects.

  2. Objective lens (United States)

    Olczak, Eugene G. (Inventor)


    An objective lens and a method for using same. The objective lens has a first end, a second end, and a plurality of optical elements. The optical elements are positioned between the first end and the second end and are at least substantially symmetric about a plane centered between the first end and the second end.

  3. A geometric model of a V-slit Sun sensor correcting for spacecraft wobble (United States)

    Mcmartin, W. P.; Gambhir, S. S.


    A V-Slit sun sensor is body-mounted on a spin-stabilized spacecraft. During injection from a parking or transfer orbit to some final orbit, the spacecraft may not be dynamically balanced. This may result in wobble about the spacecraft spin axis as the spin axis may not be aligned with the spacecraft's axis of symmetry. While the widely used models in Spacecraft Attitude Determination and Control, edited by Wertz, correct for separation, elevation, and azimuthal mounting biases, spacecraft wobble is not taken into consideration. A geometric approach is used to develop a method for measurement of the sun angle which corrects for the magnitude and phase of spacecraft wobble. The algorithm was implemented using a set of standard mathematical routines for spherical geometry on a unit sphere.

  4. Mass asymmetry and tricyclic wobble motion assessment using automated launch video analysis

    Directory of Open Access Journals (Sweden)

    Ryan Decker


    Examination of the pitch and yaw histories clearly indicates that in addition to epicyclic motion's nutation and precession oscillations, an even faster wobble amplitude is present during each spin revolution, even though some of the amplitudes of the oscillation are smaller than 0.02 degree. The results are compared to a sequence of shots where little appreciable mass asymmetries were present, and only nutation and precession frequencies are predominantly apparent in the motion history results. Magnitudes of the wobble motion are estimated and compared to product of inertia measurements of the asymmetric projectiles.

  5. Mystery of an artifact

    International Nuclear Information System (INIS)

    Tugrul, B.


    A chunk of metals and beads clustered together had been found in the city of Ashur in East Anatolia. Over the years, the environmental effects to which these burried artifacts are exposed,fused them together. The x-ray radiography of the cluster disclosed a major part of a disc with cuneiform script on it. By reading of cuneiform script from the radiograph, it was disclosed that the disc belongs to the period of Assyrian King Shalmaneser I (1274-1245 B.C.). The age of the chuck and the other artifacts which were found near the chunk could be decided. (author)

  6. Book Review: Precession, Nutation, and Wobble of the Earth (United States)

    Sterken, Christiaan; Dehant, V.; Mathews, P. M.


    This great book describes and explains observational and computational aspects of three apparently tiny changes in the Earth's motion and orientation, viz., precession, nutation, and wobble. The three introductory chapters of this book present fundamental definitions, elementary geodetic theory, and celestial/terrestrial reference systems - including transformations between reference frames. The next chapter on observational techniques describes the principle of accurate measurements of the orientation of the Earth's axis, as obtained from measurements of extra-galactic radio sources using Very Long Baseline Interferometry and GPS observations. Chapter 5 handles precession and nutation of the rigid Earth (i.e., a celestial body that cannot, by definition, deform) and the subsequent chapter takes deformation into consideration, viz., the effect of a centrifugal force caused by a constant-rate rotation that causes the Earth's shape and structure to become ellipsoidal. Deformations caused by external solar-system bodies are discussed in terms of deformability parameters. The next three chapters handle additional complex deviations: non-rigid Earth and more general Earth models, anelastic Earth parameters, and the effects of the fluid layers (i.e., ocean and atmosphere) on Earth rotation. Chapter 10 complements Chapter 7 with refinements that take into account diverse small effects such as the effect of a thermal conductive layer at the top of the core, Core Mantle and Inner Boundary coupling effects on nutation, electromagnetic coupling, and so-called topographic coupling. Chapter 11 covers comparison of observation and theory, and tells us that the present-date precision of the nutation theory is at the level of milliarcseconds in the time domain, and of a tenth of a microsecond in the frequency domain (with some exceptions). This chapter is followed by a 25-page chapter of definitions of equator, equinox, celestial intermediate pole and origin, stellar angle

  7. The Information Systems Artifact

    DEFF Research Database (Denmark)

    Chatterjee, Surtirtha; Xiao, Xiao; Elbanna, Amany


    Passionate debates regarding the defining characteristic of the “IT artifact” continue. Such debates, and also the lack of explicit consideration of the “information” element in the IT artifact, motivate us to propose a revised conception, drawing upon concepts from General Systems Theory (GST...

  8. An electrostatic lower stator axial-gap polysilicon wobble motor part I: Design and modeling

    NARCIS (Netherlands)

    Legtenberg, R.; Legtenberg, Rob; Berenschot, Johan W.; van Baar, J.J.J.; Elwenspoek, Michael Curt

    This paper presents design issues and a theoretical model of electrostatically driven axial-gap polysilicon wobble motors. The motor design benefits from large axial rotor-to-stator overlap and large gear ratios, and motor designs with rotor radii of 50 and 100 μm are capable of generating torques

  9. New determination of period and quality factor of Chandler wobble, considering geophysical excitations

    Czech Academy of Sciences Publication Activity Database

    Vondrák, Jan; Ron, Cyril; Chapanov, Y.


    Roč. 59, č. 5 (2017), s. 1395-1407 ISSN 0273-1177 R&D Projects: GA ČR GA13-15943S Institutional support: RVO:67985815 Keywords : polar motion * chandler wobble * geophysical excitations Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics OBOR OECD: Astronomy (including astrophysics,space science) Impact factor: 1.401, year: 2016

  10. Modeling for control of a kinematic wobble-yoke Stirling engine

    NARCIS (Netherlands)

    Garcia-Canseco, Eloisa; Alvarez-Aguirre, Alejandro; Scherpen, Jacquelien M. A.

    In this paper we derive the dynamical model of a four-cylinder double-acting wobble-yoke Stirling engine. In addition to the classical thermodynamics methods that dominate the literature of Stirling mechanisms, we present a control systems viewpoint to analyze the dynamic properties of the engine.

  11. The Human-Artifact Model

    DEFF Research Database (Denmark)

    Bødker, Susanne; Klokmose, Clemens Nylandsted


    needs to support such development through concepts and methods. This leads to a methodological approach that focuses on new artifacts to supplement and substitute existing artifacts. Through a design case, we develop the methodological approach and illustrate how the human–artifact model can be applied...... to analyze present artifacts and to design future ones. The model is used to structure such analysis and to reason about findings while providing leverage from activity theoretical insights on mediation, dialectics, and levels of activity....

  12. Small Artifacts - Big Technologies

    DEFF Research Database (Denmark)

    Kreiner, Kristian


    The computer IC is the heart of the information and telecommunication technology. It is a tiny artifact, but with incredible organizing powers. We use this physical artifact as the location for studying central problems of the knowledge economy. First, the paper describes the history of chip design...... and the emergence of the technological community involved in designing and manufacturing computer chips. The community is structured in a way that reflects the underlying physical nature silicon and the numerous other materials and chemicals involved. But it also reflects the human agency of defining new projects......, of visioning the liberation from atoms, of committing to travel many detours in the labyrinths of development, and of perceiving and exploring the affordance that new technologies hide. Some of these characteristics are analyzed empirically in a case study of designing a chip for a digitalized hearing...

  13. Controlling Modelling Artifacts

    DEFF Research Database (Denmark)

    Smith, Michael James Andrew; Nielson, Flemming; Nielson, Hanne Riis


    the possible configurations of the system (for example, by counting the number of components in a certain state). We motivate our methodology with a case study of the LMAC protocol for wireless sensor networks. In particular, we investigate the accuracy of a recently proposed high-level model of LMAC......When analysing the performance of a complex system, we typically build abstract models that are small enough to analyse, but still capture the relevant details of the system. But it is difficult to know whether the model accurately describes the real system, or if its behaviour is due to modelling...... artifacts that were inadvertently introduced. In this paper, we propose a novel methodology to reason about modelling artifacts, given a detailed model and a highlevel (more abstract) model of the same system. By a series of automated abstraction steps, we lift the detailed model to the same state space...

  14. Lens Model

    DEFF Research Database (Denmark)

    Nash, Ulrik William


    Firms consist of people who make decisions to achieve goals. How do these people develop the expectations which underpin the choices they make? The lens model provides one answer to this question. It was developed by cognitive psychologist Egon Brunswik (1952) to illustrate his theory...

  15. An Additive Manufacturing Test Artifact (United States)

    Moylan, Shawn; Slotwinski, John; Cooke, April; Jurrens, Kevin; Donmez, M Alkan


    A test artifact, intended for standardization, is proposed for the purpose of evaluating the performance of additive manufacturing (AM) systems. A thorough analysis of previously proposed AM test artifacts as well as experience with machining test artifacts have inspired the design of the proposed test artifact. This new artifact is designed to provide a characterization of the capabilities and limitations of an AM system, as well as to allow system improvement by linking specific errors measured in the test artifact to specific sources in the AM system. The proposed test artifact has been built in multiple materials using multiple AM technologies. The results of several of the builds are discussed, demonstrating how the measurement results can be used to characterize and improve a specific AM system. PMID:26601039

  16. Active-passive biodynamics of the human trunk when seated on a wobble chair. (United States)

    Shahvarpour, A; Shirazi-Adl, A; Larivière, C


    Unstable sitting on a wobble chair with different balance difficulty levels can be used as an effective tool in exercises as well as evaluation and therapeutic stages of rehabilitation. No data on muscle activity levels and spinal loads are however available to assess its safety compared to other regular daily activities. The goal of this study was to estimate muscle forces and spinal loads in a seated unstable wobble chair task. In vivo 3D kinematics of the trunk and seat collected in an earlier study were used here to drive computational trunk musculoskeletal models of 6 normal and 6 low-back pain subject groups sitting on a wobble chair for a duration of 10s. Results revealed no significant differences between kinematics, muscle forces, spinal loads and force plate reaction forces when comparing these two groups. The estimated muscle forces and spinal loads were moderate though larger than those in a stationary sitting posture. Local spinal forces at the L5-S1 disc varied with time and reached their peaks (1473 N and 1720 N in compression, 691 N and 687 N in posterior-anterior shear and 153 N and 208 N in right-left shear, respectively for healthy and CLBP groups) being much greater relative to those in the stationary sitting posture (means of 12 subjects: 768 N, 284 N and 0 N, respectively). The wobble chair with characteristics considered in this study is found hence safe enough as a therapeutic exercise for both healthy and low-back pain subjects. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. From Ecological Sounding Artifacts Towards Sonic Artifact Ecologies

    DEFF Research Database (Denmark)

    Erkut, Cumhur; Serafin, Stefania


    The discipline of sonic interaction design has been focused on the interaction between a single user and an artifact. This strongly limits one of the fundamental aspects of music as a social and interactive experience. In this paper we propose sonic artifact ecologies as a mean to examine...... interactions between one or many users with one or many artifacts. Case studies from a recently run workshop on product sound design are examined....

  18. Process Parameter Optimization for Wobbling Laser Spot Welding of Ti6Al4V Alloy (United States)

    Vakili-Farahani, F.; Lungershausen, J.; Wasmer, K.

    Laser beam welding (LBW) coupled with "wobble effect" (fast oscillation of the laser beam) is very promising for high precision micro-joining industry. For this process, similarly to the conventional LBW, the laser welding process parameters play a very significant role in determining the quality of a weld joint. Consequently, four process parameters (laser power, wobble frequency, number of rotations within a single laser pulse and focused position) and 5 responses (penetration, width, heat affected zone (HAZ), area of the fusion zone, area of HAZ and hardness) were investigated for spot welding of Ti6Al4V alloy (grade 5) using a design of experiments (DoE) approach. This paper presents experimental results showing the effects of variating the considered most important process parameters on the spot weld quality of Ti6Al4V alloy. Semi-empirical mathematical models were developed to correlate laser welding parameters to each of the measured weld responses. Adequacies of the models were then examined by various methods such as ANOVA. These models not only allows a better understanding of the wobble laser welding process and predict the process performance but also determines optimal process parameters. Therefore, optimal combination of process parameters was determined considering certain quality criteria set.

  19. Effect of 6 weeks wobble board exercises on static and dynamic balance of stroke survivors. (United States)

    Onigbinde, Ayodele Teslim; Awotidebe, Taofeek; Awosika, Henry


    Balance is a complex motor skill and it is frequently disturbed among stroke survivors. Rehabilitation experts are still facing challenges in achieving good stability. The primary aim of this study was to determine the effect of a wobble board exercise program on static and dynamic balance of hemiplegic subjects. Seventeen (17) stroke survivors were randomly selected into two groups. The subjects in the experimental group were trained on wobble board for six weeks while the control group received only the baseline treatment programs. The modified version of the timed balance test was used to assess balance while the foursquare step test was used to assess dynamic balance. Descriptive statistics and Analysis of variance (ANOVA) were used to analyze the data obtained. The result showed that there was significant difference in the static balance (eye closed) (F=7.49, P 0.05). The study concluded that wobble board exercise improved both static (eye closed) and dynamic balance of stroke survivor used in this study.

  20. Artifacts in Magnetic Resonance Imaging

    International Nuclear Information System (INIS)

    Krupa, Katarzyna; Bekiesińska-Figatowska, Monika


    Artifacts in magnetic resonance imaging and foreign bodies within the patient’s body may be confused with a pathology or may reduce the quality of examinations. Radiologists are frequently not informed about the medical history of patients and face postoperative/other images they are not familiar with. A gallery of such images was presented in this manuscript. A truncation artifact in the spinal cord could be misinterpreted as a syrinx. Motion artifacts caused by breathing, cardiac movement, CSF pulsation/blood flow create a ghost artifact which can be reduced by patient immobilization, or cardiac/respiratory gating. Aliasing artifacts can be eliminated by increasing the field of view. An artificially hyperintense signal on FLAIR images can result from magnetic susceptibility artifacts, CSF/vascular pulsation, motion, but can also be found in patients undergoing MRI examinations while receiving supplemental oxygen. Metallic and other foreign bodies which may be found on and in patients’ bodies are the main group of artifacts and these are the focus of this study: e.g. make-up, tattoos, hairbands, clothes, endovascular embolization, prostheses, surgical clips, intraorbital and other medical implants, etc. Knowledge of different types of artifacts and their origin, and of possible foreign bodies is necessary to eliminate them or to reduce their negative influence on MR images by adjusting acquisition parameters. It is also necessary to take them into consideration when interpreting the images. Some proposals of reducing artifacts have been mentioned. Describing in detail the procedures to avoid or limit the artifacts would go beyond the scope of this paper but technical ways to reduce them can be found in the cited literature

  1. Ambient neutron dose equivalent during proton therapy using wobbling scanning system: Measurements and calculations (United States)

    Lin, Yung-Chieh; Lee, Chung-Chi; Chao, Tsi-Chian; Tsai, Hui-Yu


    Neutron production is a concern in proton therapy, particularly in scattering proton beam delivery systems. Despite this fact, little is known about the effects of secondary neutron exposure around wobbling scattered proton treatment nozzles. The objective of this study was to estimate the neutron dose level resulting from the use of a wobbling scattered proton treatment unit. We applied the Monte Carlo method for predict the ambient neutron dose equivalent, H*(10), per absorbed dose at the treatment isocenter, D, in the proton therapy center of Chang Gung Memorial Hospital, Linkou, Taiwan. For a 190-MeV proton beam, H* (10) / D values typically decreased with the distance from the isocenter, being 1.106 mSv/Gy at the isocenter versus 0.112 mSv/Gy at a distance of 150 cm from the isocenter. The H* (10) / D values generally decreased as the neutron receptors moved away from the isocenter, and increased when the angle from the initial beam axis increased. The ambient neutron dose equivalents were observed to be slightly lower in the direction of multileaf collimator movement. For radiation protection, the central axis of a proton-treated patient is suggested to be at the 0° angle of the beam. If the beam direction at the 90° angle is necessary, the patient axis is suggested to be along with the direction of MLC movement. Our study provides the neutron dose level and neutron energy fluence for the first wobbling proton system at the proton therapy center of Chang Gung Memorial Hospital.

  2. Turquoise Artifact from Teotihuacan

    Energy Technology Data Exchange (ETDEWEB)

    Spence, Michael W.; Harbottle, Garman; Weigand, Phil C.


    Turquoise artifacts appeared sporadically in Mesoamerica as early as the Formative period (Merry de Morales 1987:100, Figure 8.4; Weigand 1989:43). Most occurrences, however, postdate the collapse of Teotihuacan. In the Late Classic and Postclassic periods increasing quantities are found, often in the form of elaborate mosaics, in a wide variety of contexts in central, west and northwest Mexico. Neutron activation analysis has determined that much of this turquoise derives from sources in the southwestern United States (Weigand et al. 1977; Harbottle and Weigand 1992; Weigand and Harbottle 1993). Teotihuacan played a major role in Mesoamerica during the Terminal Formative and Early-Middle Classic periods. It was the dominant power in central Mexico from about the time of Christ to its collapse at about A.D. 650 (Millon 1988, 1992; Cowgill 1996). Throughout this period goods flowed into Teotihuacan from many parts of the Mesoamerican world. Despite this widespread economic interaction, only two pieces of turquoise have been recovered in the city. In the following pages, the context and implications of one of these finds will be examined.

  3. Investigating media artifacts with children

    DEFF Research Database (Denmark)

    Chimirri, Niklas Alexander

    The dissertation’s aim is to explore the everyday relevance media artifacts have for young children. It discusses and further develops analytical concepts that are committed to taking the children’s perspectives on possibilities and limitations of such artifacts seriously. These conceptual...... developments are rooted in the author’s participation in a daycare practice in Berlin, Germany. The daycare’s situational approach precisely attempted to draw on the children’s everyday life experiences so as to engage in problem-oriented learning projects, on media artifacts and beyond....

  4. Contact lens in keratoconus

    Directory of Open Access Journals (Sweden)

    Varsha M Rathi


    Full Text Available Contact lenses are required for the visual improvement in patients with keratoconus. Various contact lens options, such as rigid gas permeable (RGP lenses, soft and soft toric lenses, piggy back contact lenses (PBCL, hybrid lenses and scleral lenses are availble. This article discusses about selection of a lens depending on the type of keratoconus and the fitting philosophies of various contact lenses including the starting trial lens. A Medline search was carried out for articles in the English language with the keywords keratoconus and various contact lenses such as Rose k lens, RGP lens, hybrid lens, scleral lens and PBCL.

  5. Contact lens in keratoconus (United States)

    Rathi, Varsha M; Mandathara, Preeji S; Dumpati, Srikanth


    Contact lenses are required for the visual improvement in patients with keratoconus. Various contact lens options, such as rigid gas permeable (RGP) lenses, soft and soft toric lenses, piggy back contact lenses (PBCL), hybrid lenses and scleral lenses are availble. This article discusses about selection of a lens depending on the type of keratoconus and the fitting philosophies of various contact lenses including the starting trial lens. A Medline search was carried out for articles in the English language with the keywords keratoconus and various contact lenses such as Rose k lens, RGP lens, hybrid lens, scleral lens and PBCL. PMID:23925325

  6. Wobbled electronic properties of lithium clusters: Deterministic approach through first principles (United States)

    Kushwaha, Anoop Kumar; Nayak, Saroj Kumar


    The innate tendency to form dendritic growth promoted through cluster formation leading to the failure of a Li-ion battery system have drawn significant attention of the researchers towards the effective destabilization of the cluster growth through selective implementation of electrolytic media such as acetonitrile (MeCN). In the present work, using first principles density functional theory and continuum dielectric model, we have investigated the origin of oscillatory nature of binding energy per atom of Lin (n ≤ 8) under the influence of MeCN. In the gas phase, we found that static mean polarizability is strongly correlated with binding energy and shows oscillatory nature with cluster size due to the open shell of Lin cluster. However, in acetonitrile medium, the binding energy has been correlated with electrostatic Lin -MeCN interaction and it has been found that both of them possess wobbled behavior characterized by the cluster size.

  7. New Wobble-Address Format for an Optical Disc with a Separated Guide Layer (United States)

    Ogawa, Akihito; Usui, Takashi; Okano, Hideaki; Yusu, Keiichiro; Watabe, Kazuo


    We propose a physical address format suitable for the separated guide layer of a multilayered optical disc. Since the track format of the guide layer is different from that of conventional multilayered discs, a novel address format is required. The proposed format adopts a land-and-groove-track structure to generate a stable tracking signal. The address information for land and groove tracks is physically premastered by the wobbling and width-modulating of grooves. We fabricated a replicated disc sample with the proposed format and demonstrated a sufficiently low bit error rate by an experiment. Consequently, we considered that the format is a promising solution for the physical format for multilayered discs with a separated guide layer.

  8. Effect of wobble board training on movement strategies to maintain equilibrium on unstable surfaces

    DEFF Research Database (Denmark)

    Silva, Priscila de Brito; Mrachacz-Kersting, Natalie; Oliveira, Anderson Souza


    Standing on unstable surfaces requires more complex motor control mechanisms to sustain balance when compared to firm surfaces. Surface instability enhances the demand to maintain equilibrium and is often used to challenge balance, but little is known about how balance training affects movement...... strategies to control posture while standing on unstable surfaces. This study aimed at assessing the effects of isolated wobble board (WB) training on movement strategies to maintain balance during single-leg standing on a WB. Twenty healthy men were randomly assigned to either a control or a training group....... The training group took part in four weeks of WB training and both groups were tested pre and post the intervention. Electromyography from the supporting lower limb muscles, full-body kinematics and ground reaction forces were recorded during firm surface (FS) and WB single-leg standing. WB training did...

  9. Stability of the wobbling motion in the triaxially deformed odd-A nucleus (United States)

    Tanabe, Kosai; Sugawara-Tanabe, Kazuko


    In order to analyze the content of the exact solutions for particle-rotor models with both the rigid and the hydrodynamical moments of inertia (MoI), as a theoretical probe we apply the Holstein–Primakoff (HP) boson expansion method to the total angular momentum I and the single-particle angular momentum j. We study the competition between Coriolis force and the single-particle potential by employing the different choices of the diagonal HP boson representations for the components of I and j along a common coordinate axis, and along perpendicular axes. We do not find any wobbling level sequence associated with the rotation around the principal axis with the medium MoI. The staggering in the alignments of I about the axis with the medium MoI is found in the limited range of I, while the vector R(=I-j) is confined about the axis with the largest MoI.

  10. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... lens because they can be purchased over-the-counter or on the Internet," says Thomas Steinemann, MD, ... Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume Contacts May Contain Chemicals Harmful to Eyes ...

  11. Artifact-free resizing using an optical method (United States)

    Bowron, John W.; Tsintzouras, George


    Pixelated spatial light modulators (SLMs) are commonly used in projection displays. The total number of columns and rows in the device define its `native' resolution. This native resolution may not match the resolution of the signal that is to be displayed. It is common to use electronic methods to re-scale the signal to match the resolution of the panel. This resizing introduces artifacts that may be unacceptable in some applications. A new technique is described using optical methods to obtain an artifact free representation of the signal. This method works particularly well with high- resolution 1.8' diagonal devices where the signals to be displayed have equal or lesser resolution than the SLM. The system requires a zoom illumination system and a zoom projection lens. Information is sent to a sub-area of the panel that matches the native resolution of the signal. The zoom illumination system concentrates the total light flux onto this sub-area. A zoom projection lens adjusts the size of the final image to be constant.

  12. Toddlers View Artifact Function Normatively (United States)

    Casler, Krista; Terziyan, Treysi; Greene, Kimberly


    When children use objects like adults, are they simply tracking regularities in others' object use, or are they demonstrating a normatively defined awareness that there are right and wrong ways to act? This study provides the first evidence for the latter possibility. Young 2- and 3-year-olds (n = 32) learned functions of 6 artifacts, both…

  13. Text Signals Influence Team Artifacts (United States)

    Clariana, Roy B.; Rysavy, Monica D.; Taricani, Ellen


    This exploratory quasi-experimental investigation describes the influence of text signals on team visual map artifacts. In two course sections, four-member teams were given one of two print-based text passage versions on the course-related topic "Social influence in groups" downloaded from Wikipedia; this text had two paragraphs, each…

  14. Code OK3 - An upgraded version of OK2 with beam wobbling function (United States)

    Ogoyski, A. I.; Kawata, S.; Popov, P. H.


    For computer simulations on heavy ion beam (HIB) irradiation onto a target with an arbitrary shape and structure in heavy ion fusion (HIF), the code OK2 was developed and presented in Computer Physics Communications 161 (2004). Code OK3 is an upgrade of OK2 including an important capability of wobbling beam illumination. The wobbling beam introduces a unique possibility for a smooth mechanism of inertial fusion target implosion, so that sufficient fusion energy is released to construct a fusion reactor in future. New version program summaryProgram title: OK3 Catalogue identifier: ADST_v3_0 Program summary URL: Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, No. of lines in distributed program, including test data, etc.: 221 517 No. of bytes in distributed program, including test data, etc.: 2 471 015 Distribution format: tar.gz Programming language: C++ Computer: PC (Pentium 4, 1 GHz or more recommended) Operating system: Windows or UNIX RAM: 2048 MBytes Classification: 19.7 Catalogue identifier of previous version: ADST_v2_0 Journal reference of previous version: Comput. Phys. Comm. 161 (2004) 143 Does the new version supersede the previous version?: Yes Nature of problem: In heavy ion fusion (HIF), ion cancer therapy, material processing, etc., a precise beam energy deposition is essentially important [1]. Codes OK1 and OK2 have been developed to simulate the heavy ion beam energy deposition in three-dimensional arbitrary shaped targets [2, 3]. Wobbling beam illumination is important to smooth the beam energy deposition nonuniformity in HIF, so that a uniform target implosion is realized and a sufficient fusion output energy is released. Solution method: OK3 code works on the base of OK1 and OK2 [2, 3]. The code simulates a multi-beam illumination on a target with arbitrary shape and

  15. Artifacts as Authoritative Actors in Educational Reform (United States)

    März, Virginie; Kelchtermans, Geert; Vermeir, Karen


    Educational reforms are often translated in and implemented through artifacts. Although research has frequently treated artifacts as merely functional, more recent work acknowledges the complex relationship between material artifacts and human/organizational behavior. This article aims at disentangling this relationship in order to deepen our…

  16. A sphericon-shaped magnetic millirobot rolling on a surface actuated by an external wobbling magnetic field

    Directory of Open Access Journals (Sweden)

    Seungmun Jeon


    Full Text Available This paper proposes a novel sphericon-shaped magnetic millirobot (SSMM that can roll on a variety of surfaces. The SSMM comprises four identical half cones with a cylindrical magnet inserted into the geometric center. It can roll forward or backward on a surface with repeated rolling cone motions (wobbling motions. Since a rolling SSMM develops its entire surface by means of line contact, a relatively large maximum static friction force can make the SSMM move on a surface steadily and effectively. In this work, a new type of external wobbling magnetic field (EWMF was also derived to manipulate the SSMM’s rolling motions precisely. Then, the controlled rolling motions of prototype SSMMs under various surface conditions were demonstrated to examine the rolling ability of the proposed SSMM.

  17. Streak artifacts in dynamic CT

    International Nuclear Information System (INIS)

    Partanen, K.; Kormano, M.


    Experiments with a body phantom during dynamic CT scanning with the Somatom 2 CT scanner indicate that the periodic streak artifacts seen on the anterior part of the liver in patients are caused by peristalsis of the stomach and resulting motion of the air fluid level. Therefore, the attenuation values of the anterior portion of the liver artifactually oscillate around the baseline value during the dynamic series of scans. This artifact is produced by a change in the position of the stomach air fluid level and is dependent on the direction of tube rotation. The mean of the artifactually oscillating attenuation readings is close to the mean density but usually useless in dynamic CT because the attenuation values change so rapidly in the dynamic phase that averaging measurements also will cause errors. (Auth.)

  18. Artifact

    DEFF Research Database (Denmark)


    would like to replace ‘art’ with ‘type’, in a search for the idea­typemachines of our time.We would be most honored if you would join us in our pursuit.”In the hopes of launching a non­dogmatic effort to discover the idea­type­machines of our time, a conference was held in Copenhagen in 2010, where...... uses a conceptual form of art, it means that all the planning and decisions are made beforehand and the execution is a perfunctory affair. The idea becomes a machine that makes art.’ (Sol LeWitt, ‘Paragraph on Conceptual art’, in Artforum, 1967.)We would like to draw on Sol LeWitt’s vision and then we...

  19. Artifact

    DEFF Research Database (Denmark)


    CONCEPTUAL TYPE: TYPE LED BY IDEAS 26/10/12“Where are the idealistic fonts, the artsy fonts, the non fonts, the political fonts, the funny fonts, the difficult fonts, the fonts that don’t look like fonts, the fonts that are frontiers of new beliefs? We would like to focus on the ideas and concepts...... behind type. Rather than ushering in our examination about type by asking who it was that created it and what it looks like, we want to ring in this new decade by asking why we create type and what it means.‘In conceptual art the idea or concept is the most important aspect of the work. When an artist...... designers and theorists convened to discuss the current status of typedesign with a point of departurein what was proposed on the invitation quoted above. The conference attracted more than 500 graphic designers, type designers and theorists from all over Europeand the large turnout and the huge interest...



    Petrov, P. V.; Kolchevsky, N. N.


    Compound concave refractive lenses are used for focusing neutron beam. Investigations of spectral and focusing properties of a refractive neutron lens are presented. Resolution of the imaging system on the base of refractive neutron lenses depends on material properties and parameters of neutron source. Model of refractive neutron lens are proposed. Results of calculation diffraction resolution and focal depth of refractive neutron lens are discussed.

  1. Contact lens in keratoconus


    Rathi, Varsha M; Mandathara, Preeji S; Dumpati, Srikanth


    Contact lenses are required for the visual improvement in patients with keratoconus. Various contact lens options, such as rigid gas permeable (RGP) lenses, soft and soft toric lenses, piggy back contact lenses (PBCL), hybrid lenses and scleral lenses are availble. This article discusses about selection of a lens depending on the type of keratoconus and the fitting philosophies of various contact lenses including the starting trial lens. A Medline search was carried out for articles in the En...

  2. Frequency Adaptive Control Technique for Periodic Runout and Wobble Cancellation in Optical Disk Drives

    Directory of Open Access Journals (Sweden)

    Yee-Pien Yang


    Full Text Available Periodic disturbance occurs in various applications on the control of the rotational mechanical systems. For optical disk drives, the spirally shaped tracks are usually not perfectly circular and the assembly of the disk and spindle motor is unavoidably eccentric. The resulting periodic disturbance is, therefore, synchronous with the disk rotation, and becomes particularly noticeable for the track following and focusing servo system. This paper applies a novel adaptive controller, namely Frequency Adaptive Control Technique (FACT, for rejecting the periodic runout and wobble effects in the optical disk drive with dual actuators. The control objective is to attenuate adaptively the specific frequency contents of periodic disturbances without amplifying its rest harmonics. FACT is implemented in a plug-in manner and provides a suitable framework for periodic disturbance rejection in the cases where the fundamental frequencies of the disturbance are alterable. It is shown that the convergence property of parameters in the proposed adaptive algorithm is exponentially stable. It is applicable to both the spindle modes of constant linear velocity (CLV and constant angular velocity (CAV for various operation speeds. The experiments showed that the proposed FACT has successful improvement on the tracking and focusing performance of the CD-ROM, and is extended to various compact disk drives.

  3. Artifacts that mimic ballistic magnetoresistance

    International Nuclear Information System (INIS)

    Egelhoff, W.F. . E-mail :; Gan, L.; Ettedgui, H.; Kadmon, Y.; Powell, C.J.; Chen, P.J.; Shapiro, A.J.; McMichael, R.D.; Mallett, J.J.; Moffat, T.P.; Stiles, M.D.; Svedberg, E.B.


    We have investigated the circumstances underlying recent reports of very large values of ballistic magnetoresistance (BMR) in nanocontacts between magnetic wires. We find that the geometries used are subject to artifacts due to motion of the wires that distort the nanocontact thereby changing its electrical resistance. Since these nanocontacts are often of atomic scale, reliable experiments would require stability on the atomic scale. No method for achieving such stability in macroscopic wires is apparent. We conclude that macroscopic magnetic wires cannot be used to establish the validity of the BMR effect

  4. Exposure artifacts in raster scanned equalization radiography

    International Nuclear Information System (INIS)

    Plewes, D.B.; Vogelstein, E.


    The image artifacts characteristic of a scanning chest radiographic system are reviewed. The technique employs a pulsed beam of radiation swept in an overlapping raster pattern that can result in severe ripple and scan line artifacts with improper scanning parameters. A one-dimensional treatment of the scanner geometry shows that the artifacts can be eliminated when the beam width is an integral multiple of interpulse spacing. An extension to a two-dimensional analysis indicates that with the collimator geometries employed, artifact-free images are not possible with a fixed x-ray frequency but can be achieved when a variable frequency source is used. A treatment of the sensitivity for artifact formation shows that with proper choice of scanning parameters sizable errors in beam width can be tolerated without significant artifact formation

  5. Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signaling. (United States)

    Scheidt, Viktor; Jüdes, André; Bär, Christian; Klassen, Roland; Schaffrath, Raffael


    Previous work in yeast has suggested that modification of tRNAs, in particular uridine bases in the anticodon wobble position (U34), is linked to TOR (target of rapamycin) signaling. Hence, U34 modification mutants were found to be hypersensitive to TOR inhibition by rapamycin. To study whether this involves inappropriate TOR signaling, we examined interaction between mutations in TOR pathway genes ( tip41 ∆, sap190 ∆, ppm1 ∆, rrd1 ∆) and U34 modification defects ( elp3 ∆, kti 12∆, urm1 ∆, ncs2 ∆) and found the rapamycin hypersensitivity in the latter is epistatic to drug resistance of the former. Epistasis, however, is abolished in tandem with a gln3 ∆ deletion, which inactivates transcription factor Gln3 required for TOR-sensitive activation of NCR (nitrogen catabolite repression) genes. In line with nuclear import of Gln3 being under control of TOR and dephosphorylation by the Sit4 phosphatase, we identify novel TOR-sensitive sit4 mutations that confer rapamycin resistance and importantly, mislocalise Gln3 when TOR is inhibited. This is similar to gln3 ∆ cells, which abolish the rapamycin hypersensitivity of U34 modification mutants, and suggests TOR deregulation due to tRNA undermodification operates through Gln3. In line with this, loss of U34 modifications ( elp3 ∆, urm1 ∆) enhances nuclear import of and NCR gene activation ( MEP2 , GAP1 ) by Gln3 when TOR activity is low. Strikingly, this stimulatory effect onto Gln3 is suppressed by overexpression of tRNAs that usually carry the U34 modifications. Collectively, our data suggest that proper TOR signaling requires intact tRNA modifications and that loss of U34 modifications impinges on the TOR-sensitive NCR branch via Gln3 misregulation.

  6. Effect of wobble board training on movement strategies to maintain equilibrium on unstable surfaces. (United States)

    Silva, Priscila de Brito; Mrachacz-Kersting, Natalie; Oliveira, Anderson Souza; Kersting, Uwe Gustav


    Standing on unstable surfaces requires more complex motor control mechanisms to sustain balance when compared to firm surfaces. Surface instability enhances the demand to maintain equilibrium and is often used to challenge balance, but little is known about how balance training affects movement strategies to control posture while standing on unstable surfaces. This study aimed at assessing the effects of isolated wobble board (WB) training on movement strategies to maintain balance during single-leg standing on a WB. Twenty healthy men were randomly assigned to either a control or a training group. The training group took part in four weeks of WB training and both groups were tested pre and post the intervention. Electromyography from the supporting lower limb muscles, full-body kinematics and ground reaction forces were recorded during firm surface (FS) and WB single-leg standing. WB training did not affect FS performance (p = 0.865), but tripled WB standing time (p < 0.002). Moreover, training decreased lower leg muscle activation (29-59%), leg and trunk velocities (30% and 34%, respectively), and supporting limb angular velocity (24-47% across all planes for the ankle, knee and hip joints). Post intervention standing time was significantly correlated with angular velocities at the hip (r = 0.79) and knee (r = -0.83) for controls, while it correlated significantly with contra-lateral leg (r ∼ 0.70) and trunk velocity (r = -0.74) for trained participants. These results support the assumption that WB training enhances the ability to control counter-rotation mechanisms for balance maintenance on unstable surfaces, which may be a crucial protective factor against sports injuries. Copyright © 2018. Published by Elsevier B.V.

  7. An EEG Data Investigation Using Only Artifacts (United States)


    EEG Data Investigation Using Only Artifacts 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 1 Chelsey...ORGANIZATION NAME(S) AND ADDRESS(ES) AND ADDRESS(ES) 1 Ball Aerospace – 2875 Presidential Drive , Fairborn, Ohio 45324 2 Oak Ridge Institute for Science...electroencephalogram (EEG) is a positive indicator of mental workload. However, EEG signals are easily affected by artifacts . An artifact mediation

  8. Adaptive motion compensation without blocking artifacts (United States)

    Terriberry, Timothy B.


    The Block Matching Algorithms used in most popular video codec standards introduce blocking artifacts which must be removed via residual coding or deblocking filters. Alternative transform stages that do not cause blocking artifacts, such as lapped transforms or wavelets, require motion compensation methods that do not produce blocking artifacts, since they are expensive to remove. We design a new Overlapped Block Motion Compensation (OBMC) scheme that avoids these artifacts while allowing adaptive blending window sizes. This has the potential to show significant visual quality improvements over traditional OBMC.

  9. MADR: metal artifact detection and reduction (United States)

    Jaiswal, Sunil Prasad; Ha, Sungsoo; Mueller, Klaus


    Metal in CT-imaged objects drastically reduces the quality of these images due to the severe artifacts it can cause. Most metal artifacts reduction (MAR) algorithms consider the metal-affected sinogram portions as the corrupted data and replace them via sophisticated interpolation methods. While these schemes are successful in removing the metal artifacts, they fail to recover some of the edge information. To address these problems, the frequency shift metal artifact reduction algorithm (FSMAR) was recently proposed. It exploits the information hidden in the uncorrected image and combines the high frequency (edge) components of the uncorrected image with the low frequency components of the corrected image. Although this can effectively transfer the edge information of the uncorrected image, it also introduces some unwanted artifacts. The essential problem of these algorithms is that they lack the capability of detecting the artifacts and as a result cannot discriminate between desired and undesired edges. We propose a scheme that does better in these respects. Our Metal Artifact Detection and Reduction (MADR) scheme constructs a weight map which stores whether a pixel in the uncorrected image belongs to an artifact region or a non-artifact region. This weight matrix is optimal in the Linear Minimum Mean Square Sense (LMMSE). Our results demonstrate that MADR outperforms the existing algorithms and ensures that the anatomical structures close to metal implants are better preserved.

  10. Detection of a pneumonia virus of mice (PVM) in an African hedgehog (Atelerix arbiventris) with suspected wobbly hedgehog syndrome (WHS). (United States)

    Madarame, Hiroo; Ogihara, Kikumi; Kimura, Moe; Nagai, Makoto; Omatsu, Tsutomu; Ochiai, Hideharu; Mizutani, Tetsyuya


    A pneumonia virus of mice (PVM) from an African hedgehog (Atelerix arbiventris) with suspected wobbly hedgehog syndrome (WHS) was detected and genetically characterized. The affected hedgehog had a nonsuppurative encephalitis with vacuolization of the white matter, and the brain samples yielded RNA reads highly homogeneous to PVM strain 15 (96.5% of full genomic sequence homology by analysis of next generation sequencing). PVM antigen was also detected in the brain and the lungs immunohistochemically. A PVM was strongly suggested as a causative agent of encephalitis of a hedgehog with suspected WHS. This is a first report of PVM infection in hedgehogs. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Evaluating an artifact in design science research

    CSIR Research Space (South Africa)

    Herselman, M


    Full Text Available as the artifact which was evaluated. This example from practice can contribute towards an enhanced understanding of the evaluation of DSR artifacts and the contribution of program theory during both the ex ante and ex post part of the development....

  12. Computed Tomographic Artifacts in Maxillofacial Surgery. (United States)

    Kim, Jun Ho; Arita, Emiko Saito; Pinheiro, Lucas Rodrigues; Yoshimoto, Marcelo; Watanabe, Plauto Christopher Aranha; Cortes, Arthur Rodriguez Gonzalez


    The present study aimed to present 4 cases and to undertake a systematic review on the current knowledge of the impact of cone beam computed tomographic (CBCT) artifacts on oral and maxillofacial surgical planning and follow-up. The MEDLINE (PubMed) database was searched for the period from February 2004 to February 2017, for studies on the impact of CBCT artifacts on surgical planning of oral and maxillofacial surgeries. The PRISMA statement was followed during data assessment and extraction. As a result, data extraction included information regarding: the use of CBCT to plan or follow-up oral and maxillofacial surgeries, presence and type identification of a CBCT artifact, and details on the impact of artifacts on image quality and/or surgical planning. Four cases were selected to illustrate the topic. The search strategy yielded 408 publications in MEDLINE (PubMed). An initial screening of the publications was performed using abstracts and key words. After application of exclusion criteria, a total of 11 studies were finally identified as eligible to be discussed. Studies revealed 3 main types of artifact: beam hardening, streak, and motion artifacts. Most of the studies suggest that artifacts significantly affect oral and maxillofacial surgical planning and follow-up, despite of allowing for identification of metal projectiles in cases of maxillofacial trauma. CBCT artifacts have a significant impact on oral and maxillofacial surgical planning and follow-up.

  13. Cooperative learning, problem solving and mediating artifacts

    African Journals Online (AJOL)


    or having multilingual classrooms. The language of mathematics is another symbolic artifact that may impact mathematics learning. Concrete learning materials, textbooks, and computers are physical artifacts that mediate math teaching and learning (Jurdak,. 2009). Also, it is important to consider the fact that language is a ...

  14. The Ambivalent Ontology of Digital Artifacts

    DEFF Research Database (Denmark)

    Kallinikos, Jannis; Aaltonen, Aleksi; Marton, Attila


    Digital artifacts are embedded in wider and constantly shifting ecosystems such that they become increasingly editable, interactive, reprogrammable, and distributable. This state of flux and constant transfiguration renders the value and utility of these artifacts contingent on shifting webs of f...

  15. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... new application of artificial intelligence shows whether a patient’s eyes point to high blood pressure or risk ...

  16. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... be purchased over-the-counter or on the Internet," says Thomas Steinemann, MD, professor of ophthalmology at ... ask for a prescription. There is no such thing as a "one size fits all" contact lens. ...

  17. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... had not been properly fitted by an eye care professional, the lenses stuck to my eye like ... lenses do not require the same level of care or consideration as a standard contact lens because ...

  18. Colored Contact Lens Dangers

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    Full Text Available ... sell contacts without a prescription are breaking the law, and may be fined $11,000 per violation. " ... wear any kind of contact lens. In Butler's case, the lenses caused an infection and left her ...

  19. Colored Contact Lens Dangers

    Medline Plus

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  20. Colored Contact Lens Dangers

    Medline Plus

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  1. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... Academy Jobs at the Academy Financial Relationships with Industry Medical Disclaimer Privacy Policy Terms of Service For ...

  2. Colored Contact Lens Dangers

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    Full Text Available ... in a pair of colored contact lenses, Laura Butler of Parkersburg, W.Va., had "extreme pain in ... to wear any kind of contact lens. In Butler's case, the lenses caused an infection and left ...

  3. Colored Contact Lens Dangers

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    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... use of colored contact lenses , from the U.S. Food and Drug Administration (FDA). Are the colored lenses ...

  4. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... an impulsive buy from a souvenir shop, but 10 hours after she first put in a pair ... Prescription Contact Lens Laura: Vision Loss After Just 10 Hours Robyn: Blurry Vision and Daily Eye Drops ...

  5. bubble chamber lens

    CERN Multimedia

    Before the days of electronic detectors, visual techniques were used to detect particles, using detectors such as spark chambers and bubble chambers. This plexiglass lens was used to focus the image of tracks so they could be photographed.

  6. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... Contact Lens Facts Over-the-Counter Costume Contacts May Contain Chemicals Harmful to Eyes Four Ways Over- ... without a prescription are breaking the law, and may be fined $11,000 per violation. "Many of ...

  7. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... not require the same level of care or consideration as a standard contact lens because they can ... sell contacts without a prescription are breaking the law, and may be fined $11,000 per violation. " ...

  8. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... an ophthalmologist — an eye medical doctor — who will measure each eye and talk to you about proper ...

  9. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... prescription. Follow the contact lens care directions for cleaning, disinfecting, and wearing the lenses. Never share contact ... with Industry Medical Disclaimer Privacy Policy Terms of Service For Advertisers For Media Ophthalmology Job Center © American ...

  10. Conceptual Model of Artifacts for Design Science Research

    DEFF Research Database (Denmark)

    Bækgaard, Lars


    We present a conceptual model of design science research artifacts. The model views an artifact at three levels. At the artifact level a selected artifact is viewed as a combination of material and immaterial aspects and a set of representations hereof. At the design level the selected artifact...

  11. Viscous froth lens (United States)

    Green, T. E.; Bramley, A.; Lue, L.; Grassia, P.


    Microscale models of foam structure traditionally incorporate a balance between bubble pressures and surface tension forces associated with curvature of bubble films. In particular, models for flowing foam microrheology have assumed this balance is maintained under the action of some externally imposed motion. Recently, however, a dynamic model for foam structure has been proposed, the viscous froth model, which balances the net effect of bubble pressures and surface tension to viscous dissipation forces: this permits the description of fast-flowing foam. This contribution examines the behavior of the viscous froth model when applied to a paradigm problem with a particularly simple geometry: namely, a two-dimensional bubble “lens.” The lens consists of a channel partly filled by a bubble (known as the “lens bubble”) which contacts one channel wall. An additional film (known as the “spanning film”) connects to this bubble spanning the distance from the opposite channel wall. This simple structure can be set in motion and deformed out of equilibrium by applying a pressure across the spanning film: a rich dynamical behavior results. Solutions for the lens structure steadily propagating along the channel can be computed by the viscous froth model. Perturbation solutions are obtained in the limit of a lens structure with weak applied pressures, while numerical solutions are available for higher pressures. These steadily propagating solutions suggest that small lenses move faster than large ones, while both small and large lens bubbles are quite resistant to deformation, at least for weak applied back pressures. As the applied back pressure grows, the structure with the small lens bubble remains relatively stiff, while that with the large lens bubble becomes much more compliant. However, with even further increases in the applied back pressure, a critical pressure appears to exist for which the steady-state structure loses stability and unsteady

  12. Silicon bulk micromachined hybrid dimensional artifact.

    Energy Technology Data Exchange (ETDEWEB)

    Claudet, Andre A.; Tran, Hy D.; Bauer, Todd Marks; Shilling, Katherine Meghan; Oliver, Andrew David


    A mesoscale dimensional artifact based on silicon bulk micromachining fabrication has been developed and manufactured with the intention of evaluating the artifact both on a high precision coordinate measuring machine (CMM) and video-probe based measuring systems. This hybrid artifact has features that can be located by both a touch probe and a video probe system with a k=2 uncertainty of 0.4 {micro}m, more than twice as good as a glass reference artifact. We also present evidence that this uncertainty could be lowered to as little as 50 nm (k=2). While video-probe based systems are commonly used to inspect mesoscale mechanical components, a video-probe system's certified accuracy is generally much worse than its repeatability. To solve this problem, an artifact has been developed which can be calibrated using a commercially available high-accuracy tactile system and then be used to calibrate typical production vision-based measurement systems. This allows for error mapping to a higher degree of accuracy than is possible with a glass reference artifact. Details of the designed features and manufacturing process of the hybrid dimensional artifact are given and a comparison of the designed features to the measured features of the manufactured artifact is presented and discussed. Measurement results from vision and touch probe systems are compared and evaluated to determine the capability of the manufactured artifact to serve as a calibration tool for video-probe systems. An uncertainty analysis for calibration of the artifact using a CMM is presented.

  13. G.T wobble base-pairing in Z-DNA at 1.0 A atomic resolution: the crystal structure of d(CGCGTG).


    Ho, P S; Frederick, C A; Quigley, G J; van der Marel, G A; van Boom, J H; Wang, A H; Rich, A


    The DNA oligomer d(CGCGTG) crystallizes as a Z-DNA double helix containing two guanine-thymine base pair mismatches of the wobble type. The crystal diffracts to 1 A resolution and the structure has been solved and refined. At this resolution, a large amount of information is revealed about the organization of the water molecules in the lattice generally and more specifically around the wobble base pairs. By comparing this structure with the analogous high resolution structure of d(CGCGCG) we ...

  14. A particle accelerator probes artifacts

    CERN Document Server

    Dran, J C; Salomon, J


    The AGLAE system is made up of a 2 mega volts electrostatic accelerator and of 3 irradiation lines: one leads to a vacuum enclosure in which targets are irradiated and the 2 others lines are designed to irradiate targets under an air or helium atmosphere. The AGLAE system is located in the premises of the Louvre museum in Paris and is devoted to the study of cultural objects through ion beam analysis (IBA). 4 techniques are used: -) proton-induced X-ray emission (PIXE) -) proton-induced gamma ray (PIGE) -) Rutherford backscattering spectrometry (NRS) and -) nuclear reaction analysis (NRA). A decisive progress has permitted the direct analysis of artifacts without sampling. The object itself is set just a few millimeters away from the exit window of the beam in an air or helium atmosphere. The exit window must be resistant enough to bear the atmospheric pressure and the damages caused by the proton beam but must be thin enough to not deteriorate the quality of the beam. By using a 10 sup - sup 7 m thick exit w...

  15. Goat's eye integrated with a human cataractous lens: A training model for phacoemulsification. (United States)

    Sengupta, Sabyasachi; Dhanapal, Praveen; Nath, Manas; Haripriya, Aravind; Venkatesh, Rengaraj


    A relatively simple and inexpensive technique to train surgeons in phacoemulsification using a goat's eye integrated with a human cataractous nucleus is described. The goat's eye is placed on a bed of cotton within the lumen of a cylindrical container. This is then mounted on a rectangular thermocol so that the limbus is presented at the surgical field. After making a clear corneal entry with a keratome, the trainer makes a 5-5.5 mm continuous curvilinear capsulorhexis in the anterior lens capsule, creates a crater of adequate depth in the cortex and inserts the human nucleus within this crater in the goat's capsular bag. The surgical wound is sutured, and the goat's eye is ready for training. Creating the capsulorhexis with precision and making the crater of adequate depth to snugly accommodate the human nucleus are the most important steps to prevent excessive wobbling of the nucleus while training.

  16. The Ambivalent Ontology of Digital Artifacts

    DEFF Research Database (Denmark)

    Kallinikos, Jannis; Aaltonen, Aleksi; Marton, Attila


    Digital artifacts are embedded in wider and constantly shifting ecosystems such that they become increasingly editable, interactive, reprogrammable, and distributable. This state of flux and constant transfiguration renders the value and utility of these artifacts contingent on shifting webs...... are illustrated with reference to (1) provenance and authenticity of digital documents within the overall context of archiving and social memory and (2) the content dynamics occasioned by the findability of content mediated by Internet search engines. We conclude that the steady change and transfiguration...... of digital artifacts signal a shift of epochal dimensions that calls for rethinking some of the inherited wisdom in IS research and practice....

  17. The Many Faces of Computational Artifacts

    DEFF Research Database (Denmark)

    Christensen, Lars Rune; Harper, Richard


    the computational artifacts are both coordinative, image-generating, and intended for the control of nuclear-physical and chemical processes. Furthermore, the paper entails a critique of the notion of ‘computer support’, for not capturing the diverse constitutive powers of computer technology; its types if you will....... The paper is a step towards establishing a lexicon of computational artifacts in practice. It is a call for a wider effort to systematically conceptualise the multiple and specifiable ways in which computational artifacts may be part of work activities. This is for the benefit of design and our...

  18. Familial dysautonomia (FD) patients have reduced levels of the modified wobble nucleoside mcm(5)s(2)U in tRNA. (United States)

    Karlsborn, Tony; Tükenmez, Hasan; Chen, Changchun; Byström, Anders S


    Familial dysautonomia (FD) is a recessive neurodegenerative genetic disease. FD is caused by a mutation in the IKBKAP gene resulting in a splicing defect and reduced levels of full length IKAP protein. IKAP homologues can be found in all eukaryotes and are part of a conserved six subunit protein complex, Elongator complex. Inactivation of any Elongator subunit gene in multicellular organisms cause a wide range of phenotypes, suggesting that Elongator has a pivotal role in several cellular processes. In yeast, there is convincing evidence that the main role of Elongator complex is in formation of modified wobble uridine nucleosides in tRNA and that their absence will influence translational efficiency. To date, no study has explored the possibility that FD patients display defects in formation of modified wobble uridine nucleosides as a consequence of reduced IKAP levels. In this study, we show that brain tissue and fibroblast cell lines from FD patients have reduced levels of the wobble uridine nucleoside 5-methoxycarbonylmethyl-2-thiouridine (mcm(5)s(2)U). Our findings indicate that FD could be caused by inefficient translation due to lower levels of wobble uridine nucleosides. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  19. A catoptric lens

    International Nuclear Information System (INIS)

    Rambauske, W.R.


    The invention relates to a catoptric lens for combining energies transmitted by several sources such as lasers; said lens comprising mirrors, the reflective surfaces of which have their focuses spaced from a common axis of symmetry. By means of these reflecting surfaces, which are generated by the nutation of portions of quadratic conics about the axis of symmetry, it is possible to focus the energy emmited by several lasers at the focus of the exit-mirror reflecting surface. This can be applied to thermonuclear fusion [fr

  20. Removal of high signal artifact (marching metal artifact) by the magnetic substance

    International Nuclear Information System (INIS)

    Tsuchihashi, Toshio; Iwasaki, Atsushi; Mori, Katsuhiko; Suzuki, Takeshi


    During this project, we evaluated methods to prevent high-signal artifact (marching metal artifact) that are caused by magnetic substance. Marching metal artifact is caused by the resonance frequency created by magnetic substance. Phase encoding and frequency encoding are often switched to minimize the influence that marching metal artifact have on the image. However, this method will only change the position at which marching metal artifact occur. It does not have the ability to completely prevent marching metal artifact. Our research illustrated that marching metal artifact can be prevented by changing the strength of the slice selective gradient field at the 90 deg RF pulse and 180 deg RF pulse. In other words, marching metal artifact can be prevented by changing the frequency bandwidth for the 90 deg RF pulse and 180 deg RF pulse. The incorporation of the phase correct option in the device used for our research (SIGNA LX and SIGNA CV/i) results in different slice selective gradient field strengths at the 90 deg RF pulse and the 180 deg RF pulse. This indicates that the use of phase correction enables marching metal artifact to be prevented. (author)

  1. Quadrupole magnetic lens

    International Nuclear Information System (INIS)

    Piskunov, V.A.


    The following connection of windings of electromagnet is suggested for simplification of the design of qUadrupole magnetic lens intended for use in radiotechnical and electron-optical devices. The mentioned windings are connected with each other by a bridge scheme and the variable resistors are switched in its diagonals in the lens containing four electromagnet with windings connected with two variable resistors the mobile contacts of which are connected with a direct current source. Current redistribution between left windings and right windings takes place at shift of mobile contact of variable resistor, and current redistribution between upper and low coils of electromagnets takes place at shifting mobile contact of the other variable resistor. In this case smooth and independent electron-optical misalignment of lens by two mutually perpendicular directions proceeds. Use of the given design of the lens in the oscillograph permits to use printing assembly for alignment plate and to reduce the number of connections at the expense of decreasing the number of resistors

  2. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... prescription. There is no such thing as a "one size fits all" contact lens. Lenses that are not properly fitted may scratch the eye or cause blood vessels to grow into the cornea. Even if you have perfect vision, you need to get an eye exam and a prescription ...

  3. Colored Contact Lens Dangers

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    Full Text Available ... Ophthalmologist Patient Stories Español Eye Health / News Halloween Hazard: The Hidden Dangers of Buying Decorative Contact Lenses ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ...


    CERN Multimedia


    Would the person who borrowed the large bubble chamber lens from the Microcosm workshops on the ISR please return it. This is a much used piece from our object archives. If anybody has any information about the whereabouts of this object, please contact Thank you

  5. The Lens of Chemistry (United States)

    Thalos, Mariam


    Chemistry possesses a distinctive theoretical lens--a distinctive set of theoretical concerns regarding the dynamics and transformations of a perplexing variety of organic and nonorganic substances--to which it must be faithful. Even if it is true that chemical facts bear a special (reductive) relationship to physical facts, nonetheless it will…

  6. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... wear any kind of contact lens. In Butler's case, the lenses caused an infection and left her with a corneal ... A recent article from U.S. News and World Report explains what ophthalmologists are and how they can ...

  7. bubble chamber lens

    CERN Multimedia

    Was used in a PS experiment. Before the days of electronic detectors, visual techniques were used to detect particles, using detectors such as spark chambers and bubble chambers. This plexiglass lens was used to focus the image of tracks so they could be photographed.

  8. Thermal Lens Microscope (United States)

    Uchiyama, Kenji; Hibara, Akihide; Kimura, Hiroko; Sawada, Tsuguo; Kitamori, Takehiko


    We developed a novel laser microscope based on the thermal lens effect induced by a coaxial beam comprised of excitation and probe beams. The signal generation mechanism was confirmed to be an authentic thermal lens effect from the measurement of signal and phase dependences on optical configurations between the sample and the probe beam focus, and therefore, the thermal lens effect theory could be applied. Two-point spatial resolution was determined by the spot size of the excitation beam, not by the thermal diffusion length. Sensitivity was quite high, and the detection ability, evaluated using a submicron microparticle containing dye molecules, was 0.8 zmol/μm2, hence a distribution image of trace chemical species could be obtained quantitatively. In addition, analytes are not restricted to fluorescent species, therefore, the thermal lens microscope is a promising analytical microscope. A two-dimensional image of a histamine molecule distribution, which was produced in mast cells at the femtomole level in a human nasal mucous polyp, was obtained.

  9. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... an Ophthalmologist Patient Stories Español Eye Health / News Halloween Hazard: The Hidden Dangers of Buying Decorative Contact ... After One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter ...

  10. Clinical survey of lens care in contact lens patients. (United States)

    Ky, W; Scherick, K; Stenson, S


    Overall, contact lenses provide a safe and effective modality for vision correction. However, problems do occasionally arise. Up to 80% of contact lens complications can be traced to poor patient compliance with recommended lens care guidelines. We conducted a survey to evaluate the level of patient compliance in specific areas of lens care and maintenance and to assess patient knowledge of basic contact lens information. Patients were asked to complete an anonymous 15 question survey that focused on lens care--specifically the use of contact lens cleaners, methods of disinfection, enzyme treatments, use of rewetting drops, and the frequency of follow-up exams. In addition, the survey included six true/false questions relating to contact lens care and safety. There were a total of 103 participants in the study. Approximately 24% of patients stated they never cleaned their lenses prior to disinfection, and 5% used saline solutions as their primary mode of disinfection. A sizable portion of those surveyed (43% of soft lens wearers and 71% of rigid gas permeable lens wearers) either never used enzyme cleaners or used them less than once a month. Seventy percent of patients either never used rewetting drops or used them less than once a day. Twenty-nine percent of patients consulted their eye care professionals every 2 years and 6% less often than every two years. Six questions assessed patient knowledge of contact lens care safety. Of a possible six out of six correct answers, the mean number of correct responses was 3.74. A sizable proportion of contact lens wearers do not adequately adhere to recommended contact lens care, and many have an inadequate understanding of contact lens care guidelines. Therefore, it is important that practitioners place more emphasis on patient education at the time of initial contact lens fitting and reinforce such instruction during follow-up visits.

  11. Wavelet approach to artifact noise removal from Capacitive coupled Electrocardiograph. (United States)

    Lee, Seung Min; Kim, Ko Keun; Park, Kwang Suk


    Capacitive coupled Electrocardiography (ECG) is introduced as non-invasive measurement technology for ubiquitous health care and appliance are spread out widely. Although it has many merits, however, capacitive coupled ECG is very weak for motion artifacts for its non-skin-contact property. There are many studies for artifact problems which treats all artifact signals below 0.8Hz. In our capacitive coupled ECG measurement system, artifacts exist not only below 0.8Hz but also over than 10Hz. Therefore, artifact noise removal algorithm using wavelet method is tested to reject artifact-wandered signal from measured signals. It is observed that using power calculation each decimation step, artifact-wandered signal is removed as low frequency artifacts as high frequency artifacts. Although some original ECG signal is removed with artifact signal, we could level the signal quality for long term measure which shows the best quality ECG signals as we can get.

  12. Artifacts Quantification of Metal Implants in MRI (United States)

    Vrachnis, I. N.; Vlachopoulos, G. F.; Maris, T. G.; Costaridou, L. I.


    The presence of materials with different magnetic properties, such as metal implants, causes distortion of the magnetic field locally, resulting in signal voids and pile ups, i.e. susceptibility artifacts in MRI. Quantitative and unbiased measurement of the artifact is prerequisite for optimization of acquisition parameters. In this study an image gradient based segmentation method is proposed for susceptibility artifact quantification. The method captures abrupt signal alterations by calculation of the image gradient. Then the artifact is quantified in terms of its extent by an automated cross entropy thresholding method as image area percentage. The proposed method for artifact quantification was tested in phantoms containing two orthopedic implants with significantly different magnetic permeabilities. The method was compared against a method proposed in the literature, considered as a reference, demonstrating moderate to good correlation (Spearman’s rho = 0.62 and 0.802 in case of titanium and stainless steel implants). The automated character of the proposed quantification method seems promising towards MRI acquisition parameter optimization.

  13. Metallic artifacts in magnetic resonance imaging

    International Nuclear Information System (INIS)

    Abe, Eiji; Okuyama, Koichiro; Ishikawa, Noriyuki; Hongo, Michio; Sato, Kozo; Sashi, Ryuji; Ishikawa, Eijiro.


    Seven metallic implants with different content of magnetic materials were compared in terms of the degree of MRI artifact. The degree of artifact well correlated with the total content of iron and cobalt than the total content of ferromagnets (iron, cobalt, nickel). No significant difference was observed regarding artifact among 4 titanium alloys containing very small amount of ferromagnet (0.058%-2.5%). Pedicle screws were made from different alloys in the same shape. Those screws were inserted into the swine vertebrae and artifact was evaluated by MRI. The degree of artifact was SUS316 (stainless steel)>MP-35N (cobalt alloy)>Ti-6AI-4V (titanium alloy), 1.5 Tesla>0.5 Tesla as for magnetic intensity, and T2 (gradient echo)>T2 (long SE)>proton density>T1 as for exposure condition. The condition of the site screw was inserted in the vertebral canal was detectable by T1-weighted images of titanium alloy and cobalt alloy in 0.5 Tesla and T1-weighted images of titanium alloy in 1.5 Tesla. (S.Y)

  14. Buildings as Artifacts: Heritage, Patriotism, and the Constructed Landscape

    Directory of Open Access Journals (Sweden)

    Kristin Marie Barry


    Full Text Available Architectural collections or reconstructed villages are popular tourist attractions in Europe and the United States, often promoting architecture as a demonstration of national and regional heritages. At times, these sites betray the biases of their creators, perpetuated through methods of display and their public interpretation. The architecture can be used as artifact or backdrop to promote ethics, history, or industry at the hand of curators, particularly when removed from its original context and constructed in a new one. When viewed through the lens of tourism, the collections become a constructed landscape of architectural heritage, experienced by visitors through a narrow understanding of time and place, propagated by fabricated historical connections or purposeful nationalist arrangements. Often accessorizing ‘authentic’ architectural heritage with reconstructions and reproductions, these collections suggest a skewed heritage landscape to the non-specialized visitor, emphasizing tourism over truth and entertainment over education. Following 19th century examples in Scandinavia and the broader introduction of international architecture through the 1893 World’s Columbian Exposition, early 20th century American collections at Greenfield Village and the Manitou Cliff Dwellings underscore the intent to capitalize on architectural heritage tourism, and how a diluted history is interpreted through the eyes of the modern tourist.

  15. A Language of Objects and Artifacts

    DEFF Research Database (Denmark)

    Svabo, Connie

    This is a conceptual inquiry about materiality. It gives an introductory overview to the vocabulary of materiality in a chosen selection of theories. The paper shows a language of artifacts and objects as it is used within practice-based approaches to organizational knowing. The examined...... intellectual traditions are interpretive-cultural approaches; activity theory; and sociology of translation. Similarities and differences are presented in the way these three distinct intellectual traditions conceptualize the array of material objects and artifacts which are central in the tales of practice....... The paper looks into the mediatedness of knowing and doing in organizations. The intellectual traditions which are scrutinized all agree that ‘doing’ is materially embedded – that objects and artifacts are central to both knowing and learning. But what is their understanding of materiality? With which...

  16. [Correct contact lens hygiene]. (United States)

    Blümle, S; Kaercher, T; Khaireddin, R


    Although contact lenses have long been established in ophthalmology, practical aspects of handling contact lenses is becoming increasingly less important in the clinical training as specialist for ophthalmology. Simultaneously, for many reasons injuries due to wearing contact lenses are increasing. In order to correct this discrepancy, information on contact lenses and practical experience with them must be substantially increased from a medical perspective. This review article deals with the most important aspects for prevention of complications, i.e. contact lens hygiene.

  17. Prolonging contact lens wear and making contact lens wear safer. (United States)

    Foulks, Gary N


    To summarize the present status of safety and efficacy of contact lens wear. Literature review. Ovid Medline searches were performed on records from 1966 through 2005 using keywords: keratitis, contact lens complications, extended-wear contact lenses, and silicone-hydrogel contact lenses. Patients desire comfort, clarity of vision, and prolonged contact lens wear when contact lenses are used to correct refractive error. Practitioners desire patient satisfaction but also require maintenance of the integrity of the eye and no complications that jeopardize vision or health of the eye. Improvements in the oxygen permeability of the contact lens materials, design of the contact lens and its surface, and solutions for the maintenance of the lens have reduced but not eliminated the risks of infection, inflammation, and conjunctival papillary reaction associated with contact lens wear. The lessons of past and recent history suggest that patient education and practitioner participation in the management of contact lens wear continue to be critical factors for patient satisfaction and safety in the extended wear of contact lenses. The availability of highly oxygen permeable contact lenses has increased the tolerance and safety of extended contact lens wear, but patient instruction and education in proper use and care of lenses is required and caution is advised.

  18. Cooperative learning, problem solving and mediating artifacts ...

    African Journals Online (AJOL)

    The present study deals with the influence of cooperative learning on the ability of students to solve the problems. The study also concerns the introduction of mathematical mediating artifacts as factors which effect the learning of mathematics by students. Experimental research method of pre-test and post-test types was ...

  19. [E-MTAB-587] PCR_artifacts

    NARCIS (Netherlands)

    Muino Acuna, J.M.


    WARNING: This library was yield low amount of material and it was over-amplified by PCR. This libraries are used study the robustness of several statitical methods against PCR artifacts. ChIP experiments were performed on Arabidopsis wildtype inflorescences using an antibody raised against a

  20. Information Design for Visualizing History Museum Artifacts (United States)

    Chen, Yulin; Lai, Tingsheng; Yasuda, Takami; Yokoi, Shigeki


    In the past few years, museum visualization systems have become a hot topic that attracts many researchers' interests. Several systems provide Web services for browsing museum collections through the Web. In this paper, we proposed an intelligent museum system for history museum artifacts, and described a study in which we enable access to China…

  1. A constructivist approach to artifact development

    DEFF Research Database (Denmark)

    Skytte, Hans


    This paper presents a new theory on artifact development. The theory is built on the constructivist paradigm, and the research strategy applied is the constructivist approach to grounded theory. A conceptual framework was employed for the analysis of a number of food producers and retailers. The ...

  2. Studying the Creation of Design Artifacts

    DEFF Research Database (Denmark)

    Davis, Christopher J.; Hevner, Ala n R.; Weber, Barbara


    and information systems represents a highly interconnected locus in which both the generative processes of building design artifacts and articulating constructs used to evaluate their quality take place. We address this interconnectedness with an extended process-oriented research design enabling multi...

  3. A Social Language of Objects and Artifacts

    DEFF Research Database (Denmark)

    Svabo, Connie


    This paper is an inquiry about design. It gives an introductory overview of the vocabulary of 'materiality', which is used by a chosen selection of social theories. The paper shows a language of artifacts and objjects as it is used within practice-based approaches to knowing in organization  ...

  4. Stiffness of a wobbling mass models analysed by a smooth orthogonal decomposition of the skin movement relative to the underlying bone. (United States)

    Dumas, Raphaël; Jacquelin, Eric


    The so-called soft tissue artefacts and wobbling masses have both been widely studied in biomechanics, however most of the time separately, from either a kinematics or a dynamics point of view. As such, the estimation of the stiffness of the springs connecting the wobbling masses to the rigid-body model of the lower limb, based on the in vivo displacements of the skin relative to the underling bone, has not been performed yet. For this estimation, the displacements of the skin markers in the bone-embedded coordinate systems are viewed as a proxy for the wobbling mass movement. The present study applied a structural vibration analysis method called smooth orthogonal decomposition to estimate this stiffness from retrospective simultaneous measurements of skin and intra-cortical pin markers during running, walking, cutting and hopping. For the translations about the three axes of the bone-embedded coordinate systems, the estimated stiffness coefficients (i.e. between 2.3kN/m and 55.5kN/m) as well as the corresponding forces representing the connection between bone and skin (i.e. up to 400N) and corresponding frequencies (i.e. in the band 10-30Hz) were in agreement with the literature. Consistently with the STA descriptions, the estimated stiffness coefficients were found subject- and task-specific. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. How Do Artifact Models Help Direct SPI Projects?

    DEFF Research Database (Denmark)

    Kuhrmann, Marco; Richardson, Ita


    To overcome shortcomings associated with software process improvement (SPI), we previously recommended that process engineers focus on the artifacts to be developed in SPI projects. These artifacts should define desired outcomes, rather than specific methods. During this prior research, we...

  6. Patient-related pitfalls and artifacts in nuclear medicine imaging. (United States)

    Howarth, D M; Forstrom, L A; O'Connor, M K; Thomas, P A; Cardew, A P


    Quality control in nuclear medicine is all important. This applies not only to preparation of the patient and acquisition of the image, but also to interpretation of the study. Although it may seem self-evident, it is important to remain aware of artifacts that are directly related to the patient and need special consideration. Furthermore, at times the distinction between normal variants and artifacts can be difficult. Commonly encountered patient-related artifacts include artifacts caused by attenuation, contamination artifacts, and artifacts caused by intravenous lines, tubes, and catheters. Less commonly, artifacts arise because of the use of multiple isotopes, the presence of fistulas or surgically altered anatomy, and pharmaceuticals and other substances interfering with expected radiopharmaceutical uptake and distribution. The diagnostic accuracy of nuclear medicine reporting can be improved by awareness of these patient-related artifacts. Both awareness and experience are also important when it comes to detecting and identifying normal (and abnormal) variants.

  7. Teaching and learning the nature of technical artifacts


    Frederik, I.; Sonneveld, W.; De Vries, M.J.


    Artifacts are probably our most obvious everyday encounter with technology. Therefore, a good understanding of the nature of technical artifacts is a relevant part of technological literacy. In this article we draw from the philosophy of technology to develop a conceptualization of technical artifacts that can be used for educational purposes. Furthermore we report a small exploratory empirical study to see to what extent teachers’ intuitive ideas about artifacts match with the way philosophe...

  8. Compliance among soft contact lens wearers.


    Kuzman, Tomislav; Barišić Kutija, Marija; Masnec, Sanja; Jandroković, Sonja; Mrazovac, Danijela; Jurišić, Darija; Škegro, Ivan; Kalauz, Miro; Kordić, Rajko


    Contact lens compliance is proven to be crucial for preventing lens wear-related complications because of the interdependence of the steps in lens care regime and their influence on lens system microbial contamination. Awareness of the patients' lens handling compliance as well as correct recognition of non-compliant behaviours is the basis for creating more targeted strategies for patient education. The aim of this study was to investigate compliance among soft contact lens (SCL) wearers in ...

  9. Panoramic lens applications revisited (United States)

    Thibault, Simon


    During the last few years, innovative optical design strategies to generate and control image mapping have been successful in producing high-resolution digital imagers and projectors. This new generation of panoramic lenses includes catadioptric panoramic lenses, panoramic annular lenses, visible/IR fisheye lenses, anamorphic wide-angle attachments, and visible/IR panomorph lenses. Given that a wide-angle lens images a large field of view on a limited number of pixels, a systematic pixel-to-angle mapping will help the efficient use of each pixel in the field of view. In this paper, we present several modern applications of these modern types of hemispheric lenses. Recently, surveillance and security applications have been proposed and published in Security and Defence symposium. However, modern hemispheric lens can be used in many other fields. A panoramic imaging sensor contributes most to the perception of the world. Panoramic lenses are now ready to be deployed in many optical solutions. Covered applications include, but are not limited to medical imaging (endoscope, rigiscope, fiberscope...), remote sensing (pipe inspection, crime scene investigation, archeology...), multimedia (hemispheric projector, panoramic image...). Modern panoramic technologies allow simple and efficient digital image processing and the use of standard image analysis features (motion estimation, segmentation, object tracking, pattern recognition) in the complete 360° hemispheric area.

  10. Teaching and Learning the Nature of Technical Artifacts (United States)

    Frederik, Ineke; Sonneveld, Wim; de Vries, Marc J.


    Artifacts are probably our most obvious everyday encounter with technology. Therefore, a good understanding of the nature of technical artifacts is a relevant part of technological literacy. In this article we draw from the philosophy of technology to develop a conceptualization of technical artifacts that can be used for educational purposes.…

  11. Supporting Knowledge Transfer through Decomposable Reasoning Artifacts

    Energy Technology Data Exchange (ETDEWEB)

    Pike, William A.; May, Richard A.; Turner, Alan E.


    Technology to support knowledge transfer and cooperative inquiry must offer its users the ability to effectively interpret knowledge structures produced by collaborators. Communicating the reasoning processes that underlie a finding is one method for enhancing interpretation, and can result in more effective evaluation and application of shared knowledge. In knowledge management tools, interpretation is aided by creating knowledge artifacts that can expose their provenance to scrutiny and that can be transformed into diverse representations that suit their consumers’ perspectives and preferences. We outline the information management needs of inquiring communities characterized by hypothesis generation tasks, and propose a model for communication, based in theories of hermeneutics, semiotics, and abduction, in which knowledge structures can be decomposed into the lower-level reasoning artifacts that produced them. We then present a proof-of-concept implementation for an environment to support the capture and communication of analytic products, with emphasis on the domain of intelligence analysis.

  12. Artifacts Of Spectral Analysis Of Instrument Readings (United States)

    Wise, James H.


    Report presents experimental and theoretical study of some of artifacts introduced by processing outputs of two nominally identical low-frequency-reading instruments; high-sensitivity servo-accelerometers mounted together and operating, in conjunction with signal-conditioning circuits, as seismometers. Processing involved analog-to-digital conversion with anti-aliasing filtering, followed by digital processing including frequency weighting and computation of different measures of power spectral density (PSD).

  13. Panning artifacts in digital pathology images (United States)

    Avanaki, Ali R. N.; Lanciault, Christian; Espig, Kathryn S.; Xthona, Albert; Kimpe, Tom R. L.


    In making a pathologic diagnosis, a pathologist uses cognitive processes: perception, attention, memory, and search (Pena and Andrade-Filho, 2009). Typically, this involves focus while panning from one region of a slide to another, using either a microscope in a traditional workflow or software program and display in a digital pathology workflow (DICOM Standard Committee, 2010). We theorize that during panning operation, the pathologist receives information important to diagnosis efficiency and/or correctness. As compared to an optical microscope, panning in a digital pathology image involves some visual artifacts due to the following: (i) the frame rate is finite; (ii) time varying visual signals are reconstructed using imperfect zero-order hold. Specifically, after pixel's digital drive is changed, it takes time for a pixel to emit the expected amount of light. Previous work suggests that 49% of navigation is conducted in low-power/overview with digital pathology (Molin et al., 2015), but the influence of display factors has not been measured. We conducted a reader study to establish a relationship between display frame rate, panel response time, and threshold panning speed (above which the artifacts become noticeable). Our results suggest visual tasks that involve tissue structure are more impacted by the simulated panning artifacts than those that only involve color (e.g., staining intensity estimation), and that the panning artifacts versus normalized panning speed has a peak behavior which is surprising and may change for a diagnostic task. This is work in progress and our final findings should be considered in designing future digital pathology systems.

  14. Sampling Artifacts from Conductive Silicone Tubing

    Energy Technology Data Exchange (ETDEWEB)

    Timko, Michael T.; Yu, Zhenhong; Kroll, Jesse; Jayne, John T.; Worsnop, Douglas R.; Miake-Lye, Richard C.; Onasch, Timothy B.; Liscinsky, David; Kirchstetter, Thomas W.; Destaillats, Hugo; Holder, Amara L.; Smith, Jared D.; Wilson, Kevin R.


    We report evidence that carbon impregnated conductive silicone tubing used in aerosol sampling systems can introduce two types of experimental artifacts: 1) silicon tubing dynamically absorbs carbon dioxide gas, requiring greater than 5 minutes to reach equilibrium and 2) silicone tubing emits organic contaminants containing siloxane that adsorb onto particles traveling through it and onto downstream quartz fiber filters. The consequence can be substantial for engine exhaust measurements as both artifacts directly impact calculations of particulate mass-based emission indices. The emission of contaminants from the silicone tubing can result in overestimation of organic particle mass concentrations based on real-time aerosol mass spectrometry and the off-line thermal analysis of quartz filters. The adsorption of siloxane contaminants can affect the surface properties of aerosol particles; we observed a marked reduction in the water-affinity of soot particles passed through conductive silicone tubing. These combined observations suggest that the silicone tubing artifacts may have wide consequence for the aerosol community and should, therefore, be used with caution. Gentle heating, physical and chemical properties of the particle carriers, exposure to solvents, and tubing age may influence siloxane uptake. The amount of contamination is expected to increase as the tubing surface area increases and as the particle surface area increases. The effect is observed at ambient temperature and enhanced by mild heating (<100 oC). Further evaluation is warranted.

  15. Ultrasound artifacts mimicking pleural sliding after pneumonectomy. (United States)

    Cavaliere, Franco; Zamparelli, Roberto; Soave, Maurizio P; Gargaruti, Riccardo; Scapigliati, Andrea; De Paulis, Stefano


    To determine the presence of pleural sliding on chest ultrasonography (US) in a series of patients admitted to a surgical intensive care unit (SICU). Prospective, observational study. 16-bed SICU of a University hospital. 8 patients (7 men, 1 woman), aged 64 - 73 years (mean 67.5 yrs). Seven patients underwent pneumonectomy for pulmonary neoplasms; one patient underwent an atypical lung resection after having undergone a pneumonectomy one year before. None. Chest ultrasounds were performed during mechanical ventilation and spontaneous ventilation after endotracheal tube removal. In both examinations, pleural sliding was searched bilaterally in brightness mode (B-mode) and motion mode (M-mode) on the anterior thoracic wall in the least gravitationally dependent areas. During mechanical ventilation, pleural sliding was always absent on the side of the pneumonectomy and present on the other side. During spontaneous ventilation, some artifacts mimicking pleural sliding were noted on the side of the pneumonectomy both in B-mode and M-mode (presence of the seashore sign) in all patients, except for the one patient who had undergone a pneumonectomy one year earlier. Those artifacts became more pronounced during deep breaths. Ultrasound artifacts mimicking pleural sliding may be observed in the absence of the lung and may originate from the activity of intercostal muscles since they become more evident during deep breathing. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Awe and Artifacts: Religious and Scientific Endeavor

    Directory of Open Access Journals (Sweden)

    Ionut Untea


    Full Text Available The article takes as its point of departure the reflections of Henry Adams and Jacques Ellul on the possible gradual replacement of objects used in religious worship with objects used in technological worship, and advances the hypothesis that such a substitution is unlikely. Using information from psychology, history of religions, and history of science, the perspective proposed is that of a parallel historical analogous development of both religious and scientific attitudes of awe by the use of artifacts carrying two functions: firstly, to coagulate social participation around questions dealing with humanity’s destiny and interpersonal relationships across communities, and secondly to offer cultural coherence through a communal sense of social stability, comfort, and security. I argue that, though animated by attitudes of awe (“awefull”, both leading scientists and religious founders have encountered the difficulty in representing and introducing this awe to the large public via “awesome” artifacts. The failure to represent coherently the initial awe via artifacts may give rise to “anomalous awefullness”: intolerance, persecutions, global conflicts.

  17. Crystalline lens radioprotectors

    International Nuclear Information System (INIS)

    Belkacemi, Y.; Pasquier, D.; Castelain, B.; Lartigau, E.; Warnet, J.M.


    During more than a half of century, numerous compounds have been tested in different models against radiation-induced cataract. In this report, we will review the radioprotectors that have been already tested for non-human crystalline lens protection. We will focus on the most important published studies in this topic and the mechanisms of cyto-protection reported in. vitro and in. vivo from animals. The most frequent mechanisms incriminated in the cyto-protective effect are: free radical scavenging, limitation of lipid peroxidation, modulation of cycle progression increase of intracellular reduced glutathione pool, reduction of DNA strand breaks and limitation of apoptotic cell death. Arnifostine (or Ethyol) and anethole dithiolethione (or Sulfarlem), already used clinically as chemo- and radio-protectants, could be further test?r for ocular radioprotection particularly for radiation-induced cataract. (author)

  18. Voting strategy for artifact reduction in digital breast tomosynthesis

    International Nuclear Information System (INIS)

    Wu Tao; Moore, Richard H.; Kopans, Daniel B.


    Artifacts are observed in digital breast tomosynthesis (DBT) reconstructions due to the small number of projections and the narrow angular range that are typically employed in tomosynthesis imaging. In this work, we investigate the reconstruction artifacts that are caused by high-attenuation features in breast and develop several artifact reduction methods based on a 'voting strategy'. The voting strategy identifies the projection(s) that would introduce artifacts to a voxel and rejects the projection(s) when reconstructing the voxel. Four approaches to the voting strategy were compared, including projection segmentation, maximum contribution deduction, one-step classification, and iterative classification. The projection segmentation method, based on segmentation of high-attenuation features from the projections, effectively reduces artifacts caused by metal and large calcifications that can be reliably detected and segmented from projections. The other three methods are based on the observation that contributions from artifact-inducing projections have higher value than those from normal projections. These methods attempt to identify the projection(s) that would cause artifacts by comparing contributions from different projections. Among the three methods, the iterative classification method provides the best artifact reduction; however, it can generate many false positive classifications that degrade the image quality. The maximum contribution deduction method and one-step classification method both reduce artifacts well from small calcifications, although the performance of artifact reduction is slightly better with the one-step classification. The combination of one-step classification and projection segmentation removes artifacts from both large and small calcifications

  19. Contact Lens Wear at Altitude: Subcontact Lens Bubble Formation (United States)


    incidence of (PMMA) lenses . Reported here are the results of contact lens subcontact lens bubble formation under scleral lenses at bubble studies with from formation of large bubbles greater than 6,096 m (20,000 It). With soft contact lenses , bubble under their contact lenses . They also found...always located at the limbus and were without sequela to vision or corneal epithelial integrity. scleral lenses used by Jaeckle were permeable to gases

  20. Straylight Measurements in Contact Lens Wear

    NARCIS (Netherlands)

    van der Meulen, Ivanka J. E.; Engelbrecht, Leonore A.; van Vliet, Johannes M. J.; Lapid-Gortzak, Ruth; Nieuwendaal, Carla P.; Mourits, Maarten P.; Schlingemann, Reinier O.; van den Berg, Thomas J. T. P.


    Purpose: (1) To quantify the effect of contact lens wear on straylight in rigid and soft contact lens wearers and (2) to relate findings to morphological changes and subjective complaints. Methods: Straylight was measured using the Oculus C-Quant during contact lens wear and after contact lens

  1. Metal artifact suppression in megavoltage computed tomography (United States)

    Schreiner, L. John; Rogers, Myron; Salomons, Greg; Kerr, Andrew


    There has been considerable interest in megavoltage CT (MVCT) imaging associated with the development of image guided radiation therapy. It is clear that MVCT can provide good image quality for patient setup verification with soft tissue contrast much better than noted in conventional megavoltage portal imaging. In addition, it has been observed that MVCT images exhibit considerably reduced artifacts surrounding metal implants (e.g., surgical clips, hip implants, dental fillings) compared to conventional diagnostic CT images (kVCT). When encountered, these artifacts greatly limit the usefulness of kVCT images, and a variety of solutions have been proposed to remove the artifacts, but these have met with only partial success. In this paper, we investigate the potential for CT imaging in regions surrounding metal implants using high-energy photons from a Cobalt-60 source and from a 4 MV linear accelerator. MVCT and kVCT images of contrast phantoms and a phantom containing a hip prosthesis are compared and analysed. We show that MVCT scans provide good fidelity for CT number quantification in the high-density regions of the images, and in the regions immediately adjacent to the metal implants. They also provide structural details within the high-density inserts and implants. Calculations will show that practical clinical MVCT imaging, able to detect 3% contrast objects, should be achievable with doses of about 2.5cGy. This suggests that MVCT not only has a role in radiotherapy treatment planning and guidance, but may also be indicated for surgical guidance and follow-up in regions where metal implants cannot be avoided.

  2. Accessing Cultural Artifacts Through Digital Companions

    DEFF Research Database (Denmark)

    Rehm, Matthias; Jensen, Martin Lynge


    This paper presents a study that explores how the introduction of a digital companion agent for a museum exploration game changes children’s engagement with the presented artworks. To this end, a mobile application was developed featuring a monster agent that has eaten the artworks, which the chi...... the children had now to find in the museum. Results show that in comparison to the paper-based version of the exploration game, children engaged in more interactions with the actual cultural artifacts and showed a significantly higher retention rate for details of the involved artworks....

  3. Metallic artifact in MRI after removal of orthopedic implants

    International Nuclear Information System (INIS)

    Bagheri, Mohammad Hadi; Hosseini, Mehrdad Mohammad; Emami, Mohammad Jafar; Foroughi, Amin Aiboulhassani


    Objective: The aim of the present study was to evaluate the metallic artifacts in MRI of the orthopedic patients after removal of metallic implants. Subjects and methods: From March to August 2009, 40 orthopedic patients operated for removal of orthopedic metallic implants were studied by post-operative MRI from the site of removal of implants. A grading scale of 0–3 was assigned for artifact in MR images whereby 0 was considered no artifact; and I–III were considered mild, moderate, and severe metallic artifacts, respectively. These grading records were correlated with other variables including the type, size, number, and composition of metallic devices; and the site and duration of orthopedic devices stay in the body. Results: Metallic susceptibly artifacts were detected in MRI of 18 of 40 cases (45%). Screws and pins in removed hardware were the most important factors for causing artifacts in MRI. The artifacts were found more frequently in the patients who had more screws and pins in the removed implants. Gender, age, site of implantation of the device, length of the hardware, composition of the metallic implants (stainless steel versus titanium), and duration of implantation of the hardware exerted no effect in producing metallic artifacts after removal of implants. Short TE sequences of MRI (such as T1 weighted) showed fewer artifacts. Conclusion: Susceptibility of metallic artifacts is a frequent phenomenon in MRI of patients upon removal of metallic orthopedic implants.

  4. Contact Lens Related Corneal Ulcer


    Loh, KY; Agarwal, P


    A corneal ulcer caused by infection is one of the major causes of blindness worldwide. One of the recent health concerns is the increasing incidence of corneal ulcers associated with contact lens user especially if the users fail to follow specific instruction in using their contact lenses. Risk factors associated with increased risk of contact lens related corneal ulcers are: overnight wear, long duration of continuous wear, lower socio-economic classes, smoking, dry eye and poor hygiene. Th...

  5. A course in lens design

    CERN Document Server

    Velzel, Chris


    A Course in Lens Design is an instruction in the design of image-forming optical systems. It teaches how a satisfactory design can be obtained in a straightforward way. Theory is limited to a minimum, and used to support the practical design work. The book introduces geometrical optics, optical instruments and aberrations. It gives a description of the process of lens design and of the strategies used in this process. Half of its content is devoted to the design of sixteen types of lenses, described in detail from beginning to end. This book is different from most other books on lens design because it stresses the importance of the initial phases of the design process: (paraxial) lay-out and (thin-lens) pre-design. The argument for this change of accent is that in these phases much information can be obtained about the properties of the lens to be designed. This information can be used in later phases of the design. This makes A Course in Lens Design a useful self-study book, and a suitable basis for an intro...

  6. Gabor lens theory

    International Nuclear Information System (INIS)

    Irani, A.A.


    The principle of using the space charge of an electron cloud to focus ion beams was first proposed by Gabor. Electrons are to be confined radially by means of an axial magnetic field B/sub z/ and axially by means of externally applied electric fields E/sub z/. An ion beam of charge density n/sub i/ much less than n/sub e/, the electron charge density can then be focused by the radial electric field set up by the electron cloud. The case considered here is that of a hollow cylindrical conductor charged to a potential +V with grounded rings on either side to set up the axial E/sub z/ field. A solenoid wound around the central conductor supplies the B/sub z/ field. Theoretical calculations are carried out for n/sub e/ maximum as a function of B/sub z/ due to radial confinement and V due to axial confinement and the focal length of the Gabor Lens is calculated

  7. Analysis of Institutional Artifact Cost in Management Control in a Textile Company

    Directory of Open Access Journals (Sweden)

    Rodrigo Barraco Marassi


    Full Text Available The present study aimed to analyze the process of institutionalization of artifacts in cost management control of Paraná company in the textile sector. For this, we developed descriptive, qualitative research with development of a case study conducted by semi-structured interviews, questionnaires and document analysis. The company under study was selected for accessibility and intentionally to be in the implementation phase of change in management control practices. Was structured semi-structured interviews and questionnaires based on Burns and Scapens (2000, Guerreiro et al. (2005 and Rock and Warrior (2010. The controller and an employee of the comptroller, as well as two officials involved in the supply of the information system were interviewed. The company seeks to implement new accounting and management reporting system that offers the best timing and management of costs and fixed and variable costs, cost centers, among others. The research results show that the encoding step was performed by the controller and by consulting the codified principles and institutional desires in routines, rules and regulations and so draft the proposed changes. The company has not adequately met some factors of institutionalization listed by Guerreiro et al. (2005, regarding training of the people involved, elements of repetition and perceived consequences of the implementation of change by people. By analyzing the case study and reflect the results with the lens of institutional theory, it follows that to obtain management information artifacts cost depends on appropriate processes for data collection, and even when using updated technologies, needs some several facts that this process becomes institutionalized, which may be better understood based on this lens.

  8. The effect of a 5-week wobble-board exercise intervention on ability to discriminate different degrees of ankle inversion, barefoot and wearing shoes: a study in healthy elderly. (United States)

    Waddington, Gordon S; Adams, Roger D


    There is some evidence of an improvement in falls risk in the elderly after completing a wobble-board training program. This study examined the effects of wobble-board training on ability to discriminate between different extents of ankle inversion movements in a group of older subjects, tested wearing shoes and barefoot. A randomized, controlled, crossover pilot study. Canberra region, Australia. Twenty community-dwelling subjects aged 65 to 85 participated in this study; all were in good health with no known disorder of the musculoskeletal system. The accuracy with which subjects could identify a set of ankle inversion movements of different extents was measured, with testing conducted in an upright, weightbearing stance. The effects of a 5-week training program using a wobble board modified for data logging or a period of normal activity only were assessed. Subjects underwent an ankle movement discrimination test pre- and posttraining, with shoes on and off. Greater improvement in ankle movement discrimination capability was made in subjects who underwent wobble-board training than in subjects who did not train (F(1,18)=11.2, P=.003). Active movements at the ankle were also significantly better discriminated throughout when subjects were wearing shoes than when barefoot (F(1,18)=40.6, P=.001). Training with a wobble board provides a simple in-home intervention that improves ability to differentiate between extent of movements into ankle inversion in subjects aged 65 and older. Research on trip and fall frequency after wobble-board use is needed before such training could be widely used.

  9. Contrast artifacts in tapping tip atomic force microscopy

    DEFF Research Database (Denmark)

    Kyhle, Anders; Sørensen, Alexis Hammer; Zandbergen, Julie Bjerring


    When recording images with an atomic force microscope using the resonant vibrating cantilever mode, surprising strange results are often achieved. Typical artifacts are strange contours, unexpected height shifts, and sudden changes of the apparent resolution in the acquired images. Such artifacts...... interaction. The oscillating cantilever will be in a specific swing mode according to which type of interaction is dominating, and it is the switching between these modes that is responsible for a range of artifacts observed during image acquisition. This includes the artifact often referred to as "contrast...

  10. Artifact removal from EEG data with empirical mode decomposition (United States)

    Grubov, Vadim V.; Runnova, Anastasiya E.; Efremova, Tatyana Yu.; Hramov, Alexander E.


    In the paper we propose the novel method for dealing with the physiological artifacts caused by intensive activity of facial and neck muscles and other movements in experimental human EEG recordings. The method is based on analysis of EEG signals with empirical mode decomposition (Hilbert-Huang transform). We introduce the mathematical algorithm of the method with following steps: empirical mode decomposition of EEG signal, choosing of empirical modes with artifacts, removing empirical modes with artifacts, reconstruction of the initial EEG signal. We test the method on filtration of experimental human EEG signals from movement artifacts and show high efficiency of the method.

  11. Comparing the amount of EMG activity of the selected involved muscles in ankle strategy in female athletes while standing on one leg on shuttle balance and wobble board

    Directory of Open Access Journals (Sweden)

    Mansouri R


    Full Text Available Abstract Background: It seems that using shuttle balance which has recently been produced in Iran would be beneficial in exercise prescription for preventing sports injuries and recovery. The purpose of this study is comparing the amount of the electromyography activity of involved muscles in ankle strategy while standing on one leg on shuttle balance versus wobble board. Materials and Methods: this study is a functional and cause-compare study. 15 female students 20-22 years of age having the enterance standards were selected meaningfully. The amount of EMG activity of selected muscles (Tibialis Anterior, Gastrocnemius, Rectus Femoris and Hamstring was measured while standing on one leg on two devices. The difference in means of muscles activity in both of devices was estimated using multivariate analysis of variance. Results: The results showed a significant difference between the amount of EMG activity of involved muscles (p=0.001. Also, the results of the intragroup effects showed that the electromyography activity of Tibialis Anterior, Rectus Femoris and Hamstring while standing on shuttle balance was significantly more than the activity while standing on wobble board (p0/05. Conclusion: It seems that standing on shuttle balance can make higher electromyography activity in the muscles that are involved on ankle and thigh joints, i.e. Tibialis Anterior, Rectus Femoris and Hamstring. So it is recommended that shuttle balance can be used in balance training program.

  12. Effects of a wobble board-based therapeutic exergaming system for balance training on dynamic postural stability and intrinsic motivation levels. (United States)

    Fitzgerald, Diarmaid; Trakarnratanakul, Nanthana; Smyth, Barry; Caulfield, Brian


    Randomized controlled trial. To compare the effects of wobble board exercises with and without feedback provided through integrating the wobble board movement into a computer game system, by comparing changes in postural stability and motivation. Therapeutic exergaming systems may offer a solution to poor adherence to postural control exercise regimes by improving motivation levels during exercise performance. Twenty-two healthy adults, randomly assigned to an exergaming group (n = 11) and a control group (n = 11), completed 12 exercise sessions. Dynamic postural stability was quantified at baseline and follow-up using the star excursion balance test and the dynamic postural stability index during a jump-landing task. Intrinsic motivation was measured at baseline using the Self-Motivation Inventory and at follow-up using the Intrinsic Motivation Inventory. Star excursion balance test scores showed a statistically significant (PIntrinsic Motivation Inventory showed significantly higher scores (PIntrinsic Motivation Inventory categories evaluated. The findings suggest that exercising with the therapeutic exergaming system showed similar improvements in dynamic postural stability and showed a greater level of interest and enjoyment when compared to a group doing similar balance training without the game system. Therapy, level 2b.

  13. Ghost maculopathy: an artifact on near-infrared reflectance and multicolor imaging masquerading as chorioretinal pathology. (United States)

    Pang, Claudine E; Freund, K Bailey


    To describe the features of an artifact on near-infrared reflectance and MultiColor imaging, termed "ghost maculopathy," and to illustrate how it may masquerade as true chorioretinal pathology. This was a retrospective, observational case series. The authors studied 144 eyes of 72 consecutive patients in a vitreoretinal clinical practice, reviewing multimodal imaging including color and red-free fundus photography, fundus autofluorescence (FAF), near-infrared reflectance, MultiColor imaging, and spectral-domain optical coherence tomography (SD OCT). In 36 of 144 eyes (25%), there was an appearance of a hyper-reflective spot on near-infrared reflectance and MultiColor imaging, located at the macula, nasal or superonasal to the fovea, which did not correspond to any apparent lesion on color and red-free fundus photography, FAF, or SD OCT. This spot was termed the "ghost image" in this phenomenon of "ghost maculopathy." The ghost image was present consistently on near-infrared reflectance and MultiColor imaging in all 36 eyes at every imaging encounter, showing minimal and subtle variability in its shape and location within each eye; however, it showed large interindividual variability in size, shape, location, and reflectivity between different eyes. Nine eyes were found to have a similar hyper-reflective spot resembling that in ghost maculopathy, but corresponding SD OCT images were consistent with diagnoses of choroidal nevus, age-related macular degeneration, and multifocal choroiditis. All eyes with ghost maculopathy were found to be pseudophakic with a posterior chamber intraocular lens. Ghost maculopathy is the phenomenon of an imaging artifact appearing at the macula on near-infrared reflectance and MultiColor imaging that occurs predominantly in pseudophakic patients and may be mistaken for true chorioretinal pathology. Awareness of this artifact is prudent to avoid misinterpretation of clinical findings and possible unnecessary over-investigation. Copyright

  14. [Contact lens care and maintenance]. (United States)

    Bloise, L


    All contact lenses with replacement schedules longer than daily must be maintained. At each step of their use, the lenses may be contaminated. Contact lens solutions perform the essential functions of cleaning, decontaminating and preserving the lenses to prevent infectious problems and improve wearing comfort. Contact lens contamination essentially comes from hands, cleaning solutions, cases, water and the environment. The pathogenic microorganisms are mainly Gram-negative bacteria, fungi and amoebae. Contact lens deposits may or may not have an organic origin. Their presence increases the risk of infection because they serve as a nutrient matrix for microbes, and they are responsible for wearing discomfort. Contact lens solutions differ in their composition, their mechanism of action and the concentration of the various agents. To prescribe the best lens care system to each wearer and for each material, it is necessary to be very familiar with them. Maintenance is the main cause of discomfort with contact lenses, either through improper use, solution-material incompatibility, or a reaction of the wearer to the components. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  15. Pacemaker-induced Metallic Artifacts in Coronary Computed Tomography Angiography: Clinical Feasibility of Single Energy Metal Artifact Reduction Technique. (United States)

    Takayanagi, Tomoya; Arai, Takehiro; Amanuma, Makoto; Sano, Tomonari; Ichiba, Masato; Ishizaka, Kazumasa; Sekine, Takako; Matsutani, Hideyuki; Morita, Hitomi; Takase, Shinichi


    Coronary computed tomography angiography (CCTA) in patients with pacemaker suffers from metallic lead-induced artifacts, which often interfere with accurate assessment of coronary luminal stenosis. The purpose of this study was to assess a frequency of the lead-induced artifacts and artifact-suppression effect by the single energy metal artifact reduction (SEMAR) technique. Forty-one patients with a dual-chamber pacemaker were evaluated using a 320 multi-detector row CT (MDCT). Among them, 22 patients with motion-free full data reconstruction images were the final candidates. Images with and without the SMEAR technique were subjectively compared, and the degree of metallic artifacts was compared. On images without SEMAR, severe metallic artifacts were often observed in the right coronary artery (#1, #2, #3) and distal anterior descending branch (#8). These artifacts were effectively suppressed by SEMAR, and the luminal accessibility was significantly improved in #3 and #8. While pacemaker leads often cause metallic-induced artifacts, SEMAR technique reduced the artifacts and significantly improved the accessibility of coronary lumen in #3 and #8.

  16. Medical image of the week: polysomnogram artifact

    Directory of Open Access Journals (Sweden)

    Bartell J


    Full Text Available A 54 year-old man with a past medical history of attention deficit hyperactivity disorder (ADHD, low back pain, and paroxysmal supraventricular tachycardia presented to the sleep laboratory for evaluation of sleep disordered breathing. Pertinent medications include fluoxetine, ambien, and clonazepam. His Epworth sleepiness score was 18. He had a total sleep time of 12 min. On the night of his sleep study, the patient was restless and repeatedly changed positions in bed. Figures 1 and 2 show the artifact determined to be lead displacement of O1M2 after the patient shifted in bed, inadvertently removing one of his scalp electrodes. The sine waves are 60 Hz in frequency. Once the problem was identified, the lead was quickly replaced to its proper position.

  17. Beyond the interface: Encountering artifacts in use

    DEFF Research Database (Denmark)

    Bødker, Susanne; Bannon, Liam


    in their interactions with technology. He became uncomfortable with the gap between current cognitive theories and their utility in designing better interfaces to computer systems. The other person has a background in software engineering and computer systems design. In her search for a deeper understanding of  issues...... - they are not static and unchanging. For this reason the history of technology as well as of the organization of work become very important to us when we consider the (re)design of computer artifacts for people. What we do here is similar to Christiane Floyd's enterprise in her paper on software engineering...... in HCi, she came across the cognitive science framework, but she felt that its methods did not provide much help for concrete design in real life situations. In many ways our personal histories reflect some of the developments within the HCI area - the search for more theoretical frameworks...

  18. Persuasion through artifacts: Sociological and psychological dimensions

    Directory of Open Access Journals (Sweden)

    Stroe Mihaela


    Full Text Available Research suggests that applicants use various impression management tactics during employment interviews to influence interviewers' evaluations of their performance. Yet, little research has examined inteviewers/perceptions of applicant's impression management and their degree of nonverbal influence. This PhD study examines these questions, using both quantitative and qualitative data: Do interviewers accurately perceive applicant's impression management tactics? How are these perceptions integrated into their evaluations of applicant's nonverbal behaviour? Is perception accuracy influenced by artifacts (professional clothing that interviewees wear? It has cross-cultural design, because describes the differences in European Commission interviewers' social perceptions and Romanian human resources managers on one hand, and between social perceptions of European Commission public servants and Romanian employees on the other hand, concerning 12 key concepts: persuasion, first impressions, professional image, credibility, authenticity, competence, self- confidence, self-management, self-presentation, self-promotion, impression management tactics, professional appearance.

  19. Tilting a Wobbly Chair (United States)

    Cross, Rod


    If a small object is placed under the front leg of a chair, the chair tilts backwards. If the object is placed under a rear leg, the chair tilts sideways. The effect is surprising but can be analysed in terms of elementary physics.

  20. Wobbly Corner: Magnetism (United States)

    Corbett, Lisa; Maklad, Rania; Dunne, Mick; Grace, Pierre


    During a final seminar with BA year 4 science specialist trainee teachers, the authors posed a question about the difficulties associated with understanding magnetism. The ensuing discussion focused on a number of concerns commonly identified by students, which may also be of interest to classroom teachers teaching magnetism. Issues raised…

  1. An extension to artifact-free projection overlaps

    International Nuclear Information System (INIS)

    Lin, Jianyu


    Purpose: In multipinhole single photon emission computed tomography, the overlapping of projections has been used to increase sensitivity. Avoiding artifacts in the reconstructed image associated with projection overlaps (multiplexing) is a critical issue. In our previous report, two types of artifact-free projection overlaps, i.e., projection overlaps that do not lead to artifacts in the reconstructed image, were formally defined and proved, and were validated via simulations. In this work, a new proposition is introduced to extend the previously defined type-II artifact-free projection overlaps so that a broader range of artifact-free overlaps is accommodated. One practical purpose of the new extension is to design a baffle window multipinhole system with artifact-free projection overlaps. Methods: First, the extended type-II artifact-free overlap was theoretically defined and proved. The new proposition accommodates the situation where the extended type-II artifact-free projection overlaps can be produced with incorrectly reconstructed portions in the reconstructed image. Next, to validate the theory, the extended-type-II artifact-free overlaps were employed in designing the multiplexing multipinhole spiral orbit imaging systems with a baffle window. Numerical validations were performed via simulations, where the corresponding 1-pinhole nonmultiplexing reconstruction results were used as the benchmark for artifact-free reconstructions. The mean square error (MSE) was the metric used for comparisons of noise-free reconstructed images. Noisy reconstructions were also performed as part of the validations. Results: Simulation results show that for noise-free reconstructions, the MSEs of the reconstructed images of the artifact-free multiplexing systems are very similar to those of the corresponding 1-pinhole systems. No artifacts were observed in the reconstructed images. Therefore, the testing results for artifact-free multiplexing systems designed using the

  2. Prior-based artifact correction (PBAC) in computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Heußer, Thorsten, E-mail:; Brehm, Marcus [Medical Physics in Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg (Germany); Ritschl, Ludwig [Ziehm Imaging GmbH, Donaustraße 31, 90451 Nürnberg (Germany); Sawall, Stefan; Kachelrieß, Marc [Medical Physics in Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany and Institute of Medical Physics, Friedrich–Alexander–University (FAU) of Erlangen–Nürnberg, Henkestraße 91, 91052 Erlangen (Germany)


    Purpose: Image quality in computed tomography (CT) often suffers from artifacts which may reduce the diagnostic value of the image. In many cases, these artifacts result from missing or corrupt regions in the projection data, e.g., in the case of metal, truncation, and limited angle artifacts. The authors propose a generalized correction method for different kinds of artifacts resulting from missing or corrupt data by making use of available prior knowledge to perform data completion. Methods: The proposed prior-based artifact correction (PBAC) method requires prior knowledge in form of a planning CT of the same patient or in form of a CT scan of a different patient showing the same body region. In both cases, the prior image is registered to the patient image using a deformable transformation. The registered prior is forward projected and data completion of the patient projections is performed using smooth sinogram inpainting. The obtained projection data are used to reconstruct the corrected image. Results: The authors investigate metal and truncation artifacts in patient data sets acquired with a clinical CT and limited angle artifacts in an anthropomorphic head phantom data set acquired with a gantry-based flat detector CT device. In all cases, the corrected images obtained by PBAC are nearly artifact-free. Compared to conventional correction methods, PBAC achieves better artifact suppression while preserving the patient-specific anatomy at the same time. Further, the authors show that prominent anatomical details in the prior image seem to have only minor impact on the correction result. Conclusions: The results show that PBAC has the potential to effectively correct for metal, truncation, and limited angle artifacts if adequate prior data are available. Since the proposed method makes use of a generalized algorithm, PBAC may also be applicable to other artifacts resulting from missing or corrupt data.

  3. Prior-based artifact correction (PBAC) in computed tomography

    International Nuclear Information System (INIS)

    Heußer, Thorsten; Brehm, Marcus; Ritschl, Ludwig; Sawall, Stefan; Kachelrieß, Marc


    Purpose: Image quality in computed tomography (CT) often suffers from artifacts which may reduce the diagnostic value of the image. In many cases, these artifacts result from missing or corrupt regions in the projection data, e.g., in the case of metal, truncation, and limited angle artifacts. The authors propose a generalized correction method for different kinds of artifacts resulting from missing or corrupt data by making use of available prior knowledge to perform data completion. Methods: The proposed prior-based artifact correction (PBAC) method requires prior knowledge in form of a planning CT of the same patient or in form of a CT scan of a different patient showing the same body region. In both cases, the prior image is registered to the patient image using a deformable transformation. The registered prior is forward projected and data completion of the patient projections is performed using smooth sinogram inpainting. The obtained projection data are used to reconstruct the corrected image. Results: The authors investigate metal and truncation artifacts in patient data sets acquired with a clinical CT and limited angle artifacts in an anthropomorphic head phantom data set acquired with a gantry-based flat detector CT device. In all cases, the corrected images obtained by PBAC are nearly artifact-free. Compared to conventional correction methods, PBAC achieves better artifact suppression while preserving the patient-specific anatomy at the same time. Further, the authors show that prominent anatomical details in the prior image seem to have only minor impact on the correction result. Conclusions: The results show that PBAC has the potential to effectively correct for metal, truncation, and limited angle artifacts if adequate prior data are available. Since the proposed method makes use of a generalized algorithm, PBAC may also be applicable to other artifacts resulting from missing or corrupt data

  4. The SNAP Strong Lens Survey

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, P.


    Basic considerations of lens detection and identification indicate that a wide field survey of the types planned for weak lensing and Type Ia SNe with SNAP are close to optimal for the optical detection of strong lenses. Such a ''piggy-back'' survey might be expected even pessimistically to provide a catalogue of a few thousand new strong lenses, with the numbers dominated by systems of faint blue galaxies lensed by foreground ellipticals. After sketching out our strategy for detecting and measuring these galaxy lenses using the SNAP images, we discuss some of the scientific applications of such a large sample of gravitational lenses: in particular we comment on the partition of information between lens structure, the source population properties and cosmology. Understanding this partitioning is key to assessing strong lens cosmography's value as a cosmological probe.

  5. Automated Fresnel lens tester system

    Energy Technology Data Exchange (ETDEWEB)

    Phipps, G.S.


    An automated data collection system controlled by a desktop computer has been developed for testing Fresnel concentrators (lenses) intended for solar energy applications. The system maps the two-dimensional irradiance pattern (image) formed in a plane parallel to the lens, whereas the lens and detector assembly track the sun. A point detector silicon diode (0.5-mm-dia active area) measures the irradiance at each point of an operator-defined rectilinear grid of data positions. Comparison with a second detector measuring solar insolation levels results in solar concentration ratios over the image plane. Summation of image plane energies allows calculation of lens efficiencies for various solar cell sizes. Various graphical plots of concentration ratio data help to visualize energy distribution patterns.

  6. Compliance among soft contact lens wearers. (United States)

    Kuzman, Tomislav; Kutija, Marija Barisić; Masnec, Sanja; Jandroković, Sonja; Mrazovac, Danijela; Jurisić, Darija; Skegro, Ivan; Kalauz, Miro; Kordić, Rajko


    Contact lens compliance is proven to be crucial for preventing lens wear-related complications because of the interdependence of the steps in lens care regime and their influence on lens system microbial contamination. Awareness of the patients' lens handling compliance as well as correct recognition of non-compliant behaviours is the basis for creating more targeted strategies for patient education. The aim of this study was to investigate compliance among soft contact lens (SCL) wearers in different aspects of lens care handling and wearing habits. In our research 50 asymptomatic lens wearers filled out a questionnaire containing demographic data, lens type, hygiene and wearing habits, lenses and lens care system replacement schedule and self-evaluation of contact lens handling hygiene. We established criteria of compliance according to available manufacturer's recommendations, prior literature and our clinical experience. Only 2 (4%) of patients were fully compliant SCL wearers. The most common non-compliant behaviours were insufficient lens solution soaking time (62%), followed by failure to daily exchange lens case solution and showering while wearing lenses. 44% of patients reported storing lenses in saline solution. Mean lens storage case replacement was 3.6 months, with up to 78% patients replacing lens case at least once in 3 months. Average grade in self evaluating level of compliance was very good (4 +/- 0.78) (from 1-poor level of hygiene to 5-great level of hygiene). Lens wearers who reported excessive daily lens wear and more than 10 years of lens wearing experience were also found to be less compliant with other lens system care procedures. (t = -2.99, df=47, p lens system maintenance steps. Most common non-compliant behaviours were the ones that are crucial for maintaining lens sterility and preventing infection. Despite the low objective compliance rate, self grading was relatively high. Therefore, these results indicate the need for patient

  7. Teaching and learning the nature of technical artifacts

    NARCIS (Netherlands)

    Frederik, I.; Sonneveld, W.; De Vries, M.J.


    Artifacts are probably our most obvious everyday encounter with technology. Therefore, a good understanding of the nature of technical artifacts is a relevant part of technological literacy. In this article we draw from the philosophy of technology to develop a conceptualization of technical

  8. Kindergarten Children's Perceptions of "Anthropomorphic Artifacts" with Adaptive Behavior (United States)

    Kuperman, Asi; Mioduser, David


    In recent years, children from a kindergarten in central Israel have been exposed to learning experiences in technology as part of the implementation of a curriculum based on technological thinking, including topics related to behaving-adaptive-artifacts (e.g., robots). This study aims to unveil children's stance towards behaving artifacts:…

  9. Making Digital Artifacts on the Web Verifiable and Reliable

    NARCIS (Netherlands)

    Kuhn, T.; Dumontier, M.


    The current Web has no general mechanisms to make digital artifacts - such as datasets, code, texts, and images - verifiable and permanent. For digital artifacts that are supposed to be immutable, there is moreover no commonly accepted method to enforce this immutability. These shortcomings have a

  10. On Lifecycle Constraints of Artifact-Centric Workflows (United States)

    Kucukoguz, Esra; Su, Jianwen

    Data plays a fundamental role in modeling and management of business processes and workflows. Among the recent "data-aware" workflow models, artifact-centric models are particularly interesting. (Business) artifacts are the key data entities that are used in workflows and can reflect both the business logic and the execution states of a running workflow. The notion of artifacts succinctly captures the fluidity aspect of data during workflow executions. However, much of the technical dimension concerning artifacts in workflows is not well understood. In this paper, we study a key concept of an artifact "lifecycle". In particular, we allow declarative specifications/constraints of artifact lifecycle in the spirit of DecSerFlow, and formulate the notion of lifecycle as the set of all possible paths an artifact can navigate through. We investigate two technical problems: (Compliance) does a given workflow (schema) contain only lifecycle allowed by a constraint? And (automated construction) from a given lifecycle specification (constraint), is it possible to construct a "compliant" workflow? The study is based on a new formal variant of artifact-centric workflow model called "ArtiNets" and two classes of lifecycle constraints named "regular" and "counting" constraints. We present a range of technical results concerning compliance and automated construction, including: (1) compliance is decidable when workflow is atomic or constraints are regular, (2) for each constraint, we can always construct a workflow that satisfies the constraint, and (3) sufficient conditions where atomic workflows can be constructed.

  11. 76 FR 25378 - Arts and Artifacts Indemnity Panel Advisory; Committee (United States)


    ... THE ARTS AND THE HUMANITIES Federal Council on the Arts and the Humanities Arts and Artifacts...) notice is hereby given that a meeting of the Arts and Artifacts Indemnity Panel of the Federal Council on the Arts and the Humanities will be held at 1100 Pennsylvania Avenue, NW., Washington, DC 20506, in...

  12. Incidental ferumoxytol artifacts in clinical brain MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Bowser, Bruce A.; Campeau, Norbert G.; Carr, Carrie M.; Diehn, Felix E.; McDonald, Jennifer S.; Miller, Gary M.; Kaufmann, Timothy J. [Mayo Clinic, Department of Radiology, Rochester, MN (United States)


    Ferumoxytol (Feraheme) is a parenteral therapy approved for treatment of iron deficiency anemia. The product insert for ferumoxytol states that it may affect the diagnostic ability of MRI for up to 3 months. However, the expected effects may not be commonly recognized among clinical neuroradiologists. Our purpose is to describe the artifacts we have seen at our institution during routine clinical practice. We reviewed the patients at our institution that had brain MRI performed within 90 days of receiving intravenous ferumoxytol. The imaging was reviewed for specific findings, including diffusion-weighted imaging vascular susceptibility artifact, gradient-echo echo-planar T2*-weighted vascular susceptibility artifact, SWI/SWAN vascular susceptibility artifact, hypointense vascular signal on T2-weighted images, pre-gadolinium contrast vascular enhancement on magnetization-prepared rapid acquisition gradient echo (MPRAGE) imaging, and effects on post-gadolinium contrast T1 imaging. Multiple artifacts were observed in patients having a brain MRI within 3 days of receiving intravenous ferumoxytol. These included susceptibility artifact on DWI, GRE, and SWAN/SWI imaging, pre-gadolinium contrast increased vascular signal on MPRAGE imaging, and decreased expected enhancement on post-gadolinium contrast T1-weighted imaging. Ferumoxytol can create imaging artifacts which complicate clinical interpretation when brain MRI is performed within 3 days of administration. Recognition of the constellation of artifacts produced by ferumoxytol is important in order to obviate additional unnecessary examinations and mitigate errors in interpretation. (orig.)

  13. Quantification of Rain Induced Artifacts on Digital Satellite Television ...

    African Journals Online (AJOL)

    The presence of artifacts on the high definition television (TV) content and the eventual loss of the digital TV signals to rain is still a major concern to satellite operators, digital satellite television (DSTV) and terrestrial television content providers. In this paper, the artifacts present in a typical DSTV signal is examined on a ...

  14. Computer-aided lens assembly (United States)

    Tomlinson, Richard; Alcock, Rob; Petzing, Jon; Coupland, Jeremy


    We propose a computer-aided method of lens manufacture that allows assembly, adjustment, and test phases to be run concurrently until an acceptable level of optical performance is reached. Misalignment of elements within a compound lens is determined by a comparison of the results of physical ray tracing by use of an array of Gaussian laser beams with numerically obtained geometric ray traces. An estimate of misalignment errors is made, and individual elements are adjusted in an iterative manner until performance criteria are achieved. The method is illustrated for the alignment of an air-spaced doublet.

  15. Acanthamoeba keratitis. Contact lens and noncontact lens characteristics. (United States)

    Chynn, E W; Lopez, M A; Pavan-Langston, D; Talamo, J H


    To identify potential differences in time to diagnosis and final visual outcome between contact lens and noncontact lens users with Acanthamoeba keratitis. Prior studies have shown early diagnosis and therapy to be related to outcome but have not analyzed differences among patients with and without contact lenses. A retrospective analysis of 11 consecutive cases (involving 13 eyes) of Acanthamoeba keratitis diagnosed at one institution over a 3-year period. Mean time to diagnosis was significantly longer in noncontact lens users versus those who wore contact lenses (mean, 5.8 versus 3.3 weeks). Fifty percent of patients who did not wear contact lenses had a poor outcome (visual acuity worse than 20/40 or penetrating keratoplasty) versus 14% of patients who wore contact lenses. Diagnoses were made later in patients without contact lenses, and these patients had a worse visual outcome than those with Acanthamoeba keratitis who wore contact lenses. All patients with unresponsive microbial keratitis, even those without contact lens use, should be evaluated for Acanthamoeba.

  16. Distributed Cognition and Distributed Morality: Agency, Artifacts and Systems. (United States)

    Heersmink, Richard


    There are various philosophical approaches and theories describing the intimate relation people have to artifacts. In this paper, I explore the relation between two such theories, namely distributed cognition and distributed morality theory. I point out a number of similarities and differences in these views regarding the ontological status they attribute to artifacts and the larger systems they are part of. Having evaluated and compared these views, I continue by focussing on the way cognitive artifacts are used in moral practice. I specifically conceptualise how such artifacts (a) scaffold and extend moral reasoning and decision-making processes, (b) have a certain moral status which is contingent on their cognitive status, and (c) whether responsibility can be attributed to distributed systems. This paper is primarily written for those interested in the intersection of cognitive and moral theory as it relates to artifacts, but also for those independently interested in philosophical debates in extended and distributed cognition and ethics of (cognitive) technology.

  17. A microcapillary lens for X-rays

    CERN Document Server

    Dudchik, Y I


    A new design of a compound refractive lens for X-rays is proposed. The lens is made as a set of glue microlenses placed in a glass capillary. The technique of lens fabrication is described. Results of ray tracing calculations for 8 and 15 keV photons are represented.

  18. [Joint correction for motion artifacts and off-resonance artifacts in multi-shot diffusion magnetic resonance imaging]. (United States)

    Wu, Wenchuan; Fang, Sheng; Guo, Hua


    Aiming at motion artifacts and off-resonance artifacts in multi-shot diffusion magnetic resonance imaging (MRI), we proposed a joint correction method in this paper to correct the two kinds of artifacts simultaneously without additional acquisition of navigation data and field map. We utilized the proposed method using multi-shot variable density spiral sequence to acquire MRI data and used auto-focusing technique for image deblurring. We also used direct method or iterative method to correct motion induced phase errors in the process of deblurring. In vivo MRI experiments demonstrated that the proposed method could effectively suppress motion artifacts and off-resonance artifacts and achieve images with fine structures. In addition, the scan time was not increased in applying the proposed method.

  19. The Ultrawideband Leaky Lens Antenna

    NARCIS (Netherlands)

    Bruni, S.; Neto, A.; Marliani, F.


    A novel directive and nondispersive antenna is presented: the ultrawideband (UWB) leaky lens. It is based on the broad band Cherenkov radiation occurring at a slot printed between different infinite homogeneous dielectrics. The first part of the paper presents the antenna concept and the UWB design.


    Directory of Open Access Journals (Sweden)

    Vladimir Pfeifer


    Full Text Available Background. Ectopia lentis continues to be a therapeutic challenge for ophthalmologists. It can occur as an isolated condition, after ocular trauma, in association with other ocular disorders, as part of a systemic mesodermal disease or a complication of general metabolic disorders. Minimal subluxation of the lens may cause no visual symptoms, but in more advanced cases serious optical disturbances arise. The most important is amblyopia. Surgical treatment options include iris manipulation, lens discission, aspiration, intracapsular or extracapsular extraction, and pars plana lensectomy. The choice of surgical technique remains controversial, in part because of the historically poor visual results and high rate of perioperative complications, including vitreous loss and retinal detachment.Methods. We describe a surgical technique based on the use of the Cionni endocapsular tension ring, dry irrigation aspiration of lens material, centration of the capsular bag and foldable intraocular lens implantation into the bag. With mentioned surgical technique 8 patients were operated; 4 boys and 4 girls, together 11 eyes.Results. The final BCVA after follow up period improved in 9 eyes and it remained the same as before operation in one eye. Statistical comparison of preoperative and postoperative visual acuities showed significant improvement. On the other hand there was no correlation between preoperative and postoperative visual acuity.Conclusions. This surgical procedure is an alternative approach in solving this challenging cases of ectopia lentis with good postoperative visual rehabilitation.

  1. Spinning pipe gas lens revisited

    CSIR Research Space (South Africa)

    Mafusire, C


    Full Text Available , there is little information on optical phase aberrations and no study to date on the propagation parameters of the laser beam, but has rather remained rooted in the domain of ray optics. Researchers revisit the spinning pipe gas lens in this paper with new...

  2. Tube entrance lens focus control (United States)

    Weisser, D. C.; Fifield, L. K.; Kitchen, T. F. G.; Tunningley, T. B.; Lobanov, N. R.; Muirhead, A. G.


    The entrance of the accelerator tube in a large electrostatic accelerator imposes a strong lens that dominates the beam optics. The magnification of the lens is large because of the low injection energy, the high voltage gradient of the acceleration tube and the long distance to the terminal. In the absence of the acceleration, the magnification would produce an unacceptably large beam spot at the terminal. The tyranny of the lens is especially irksome when the accelerator is required to operate at a lower terminal voltage than the one corresponding to the nominal gradient at high voltage. One way around the difficulty, used in NEC Pelletron accelerators, is to insert a series of nylon and steel rods that short together units of the acceleration structure at the terminal leaving the ones near the entrance close to the nominal gradient for optimum transmission. This operation takes time and risks the loss of insulating gas. Another alternative used in the 25URC at Oak Ridge National Laboratory, is to focus the beam at the tube entrance, substantially diluting the effect of the entrance lens. The beam then diverges and so requires an additional lens part way to the terminal. This solution is only partially effective and still necessitates use of shorting rods for low voltage operation. The fact that these elaborate strategies are used is evidence that the alternative of lowering the injection energy as the terminal voltage is lowered imposes enough problems that it is not used in practice. We have modeled a solution that controls the voltage gradient at the tube entrance using an external power supply. This not only maintains the focusing effect of the lens but provides the opportunity to tune the beam by adjusting the entrance lens. A 150 kV power supply outside the pressure vessel feeds a controllable voltage through a high voltage feed-through to the fifth electrode of the accelerator tube. Thus 150 kV on this electrode creates the nominal gradient of 30 kV per

  3. Adiabatic Low-Pass J Filters for Artifact Suppression in Heteronuclear NMR

    DEFF Research Database (Denmark)

    Meier, Sebastian; Benie, Andrew J; Duus, Jens Øllgaard


    NMR artifact purging: Modern NMR experiments depend on efficient coherence transfer pathways for their sensitivity and on suppression of undesired pathways leading to artifacts for their spectral clarity. A novel robust adiabatic element suppresses hard-to-get-at artifacts....

  4. Lens stem cells may reside outside the lens capsule: an hypothesis

    Directory of Open Access Journals (Sweden)

    Meyer Rita A


    Full Text Available Abstract In this paper, we consider the ocular lens in the context of contemporary developments in biological ideas. We attempt to reconcile lens biology with stem cell concepts and a dearth of lens tumors. Historically, the lens has been viewed as a closed system, in which cells at the periphery of the lens epithelium differentiate into fiber cells. Theoretical considerations led us to question whether the intracapsular lens is indeed self-contained. Since stem cells generate tumors and the lens does not naturally develop tumors, we reasoned that lens stem cells may not be present within the capsule. We hypothesize that lens stem cells reside outside the lens capsule, in the nearby ciliary body. Our ideas challenge the existing lens biology paradigm. We begin our discussion with lens background information, in order to describe our lens stem cell hypothesis in the context of published data. Then we present the ciliary body as a possible source for lens stem cells, and conclude by comparing the ocular lens with the corneal epithelium.

  5. Searching for alien artifacts on the moon (United States)

    Davies, P. C. W.; Wagner, R. V.


    The Search for Extraterrestrial Intelligence (SETI) has a low probability of success, but it would have a high impact if successful. Therefore it makes sense to widen the search as much as possible within the confines of the modest budget and limited resources currently available. To date, SETI has been dominated by the paradigm of seeking deliberately beamed radio messages. However, indirect evidence for extraterrestrial intelligence could come from any incontrovertible signatures of non-human technology. Existing searchable databases from astronomy, biology, earth and planetary sciences all offer low-cost opportunities to seek a footprint of extraterrestrial technology. In this paper we take as a case study one particular new and rapidly-expanding database: the photographic mapping of the Moon's surface by the Lunar Reconnaissance Orbiter (LRO) to 0.5 m resolution. Although there is only a tiny probability that alien technology would have left traces on the moon in the form of an artifact or surface modification of lunar features, this location has the virtue of being close, and of preserving traces for an immense duration. Systematic scrutiny of the LRO photographic images is being routinely conducted anyway for planetary science purposes, and this program could readily be expanded and outsourced at little extra cost to accommodate SETI goals, after the fashion of the SETI@home and Galaxy Zoo projects.

  6. Colorectal Cancer "Methylator Phenotype": Fact or Artifact?

    Directory of Open Access Journals (Sweden)

    Charles Anacleto


    Full Text Available It has been proposed that human colorectal tumors can be classified into two groups: one in which methylation is rare, and another with methylation of several loci associated with a "CpG island methylated phenotype (CIMP," characterized by preferential proximal location in the colon, but otherwise poorly defined. There is considerable overlap between this putative methylator phenotype and the well-known mutator phenotype associated with microsatellite instability (MSI. We have examined hypermethylation of the promoter region of five genes (DAPK, MGMT, hMLH1, p16INK4a, and p14ARF in 106 primary colorectal cancers. A graph depicting the frequency of methylated loci in the series of tumors showed a continuous, monotonically decreasing distribution quite different from the previously claimed discontinuity. We observed a significant association between the presence of three or more methylated loci and the proximal location of the tumors. However, if we remove from analysis the tumors with hMLH1 methylation or those with MSI, the significance vanishes, suggesting that the association between multiple methylations and proximal location was indirect due to the correlation with MSI. Thus, our data do not support the independent existence of the so-called methylator phenotype and suggest that it rather may represent a statistical artifact caused by confounding of associations.

  7. YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors

    DEFF Research Database (Denmark)

    Benítez-Páez, Alfonso; Villarroya, Magda; Douthwaite, Stephen Roger


    to uncover candidate E. coli genes for the missing enzyme(s). Transfer RNAs from null mutants for candidate genes were analyzed by mass spectrometry and revealed that inactivation of yibK leads to loss of 2'-O-methylation at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Loss of Yib...... of the wobble nucleotide; YibK recognition of this target requires a pyridine at position 34 and N⁶-(isopentenyl)-2-methylthioadenosine at position 37. YibK is one of the last remaining E. coli tRNA modification enzymes to be identified and is now renamed TrmL.......Transfer RNAs are the most densely modified nucleic acid molecules in living cells. In Escherichia coli, more than 30 nucleoside modifications have been characterized, ranging from methylations and pseudouridylations to more complex additions that require multiple enzymatic steps. Most...

  8. An observer model for quantifying panning artifacts in digital pathology (United States)

    Avanaki, Ali R. N.; Espig, Kathryn S.; Xthona, Albert; Lanciault, Christian; Kimpe, Tom R. L.


    Typically, pathologists pan from one region of a slide to another, choosing areas of interest for closer inspection. Due to finite frame rate and imperfect zero-order hold reconstruction (i.e., the non-zero time to reach the target brightness after a change in pixel drive), panning in whole slide images (WSI) cause visual artifacts. It is important to study the impact of such artifacts since research suggests that 49% of navigation is conducted in low-power/overview with digital pathology (Molin et al., Histopathology 2015). In this paper, we explain what types of medical information may be harmed by panning artifacts, propose a method to simulate panning artifacts, and design an observer model to predict the impact of panning artifacts on typical human observers' performance in basic diagnostically relevant visual tasks. The proposed observer model is based on derivation of perceived object border maps from luminance and chrominance information and may be tuned to account for visual acuity of the human observer to be modeled. Our results suggest that increasing the contrast (e.g., using a wide gamut display) with a slow response panel may not mitigate the panning artifacts which mostly affect visual tasks involving spatial discrimination of objects (e.g., normal vs abnormal structure, cell type and spatial relationships between them, and low-power nuclear morphology), and that the panning artifacts worsen with increasing panning speed. The proposed methods may be used as building blocks in an automatic WSI quality assessment framework.

  9. Modern lens antennas for communications engineering

    CERN Document Server

    Thornton, John


    The aim of this book is to present the modern design principles and analysis of lens antennas. It gives graduates and RF/Microwave professionals the design insights in order to make full use of lens antennas.  Why do we want to write a book in lens antennas? Because this topic has not been thoroughly publicized, its importance is underestimated. As antennas play a key role in communication systems, recent development in wireless communications would indeed benefit from the characteristics of lens antennas: low profile, and low cost etc.  The major advantages of lens antennas are na

  10. Wide-field computational imaging of pathology slides using lens-free on-chip microscopy. (United States)

    Greenbaum, Alon; Zhang, Yibo; Feizi, Alborz; Chung, Ping-Luen; Luo, Wei; Kandukuri, Shivani R; Ozcan, Aydogan


    Optical examination of microscale features in pathology slides is one of the gold standards to diagnose disease. However, the use of conventional light microscopes is partially limited owing to their relatively high cost, bulkiness of lens-based optics, small field of view (FOV), and requirements for lateral scanning and three-dimensional (3D) focus adjustment. We illustrate the performance of a computational lens-free, holographic on-chip microscope that uses the transport-of-intensity equation, multi-height iterative phase retrieval, and rotational field transformations to perform wide-FOV imaging of pathology samples with comparable image quality to a traditional transmission lens-based microscope. The holographically reconstructed image can be digitally focused at any depth within the object FOV (after image capture) without the need for mechanical focus adjustment and is also digitally corrected for artifacts arising from uncontrolled tilting and height variations between the sample and sensor planes. Using this lens-free on-chip microscope, we successfully imaged invasive carcinoma cells within human breast sections, Papanicolaou smears revealing a high-grade squamous intraepithelial lesion, and sickle cell anemia blood smears over a FOV of 20.5 mm(2). The resulting wide-field lens-free images had sufficient image resolution and contrast for clinical evaluation, as demonstrated by a pathologist's blinded diagnosis of breast cancer tissue samples, achieving an overall accuracy of ~99%. By providing high-resolution images of large-area pathology samples with 3D digital focus adjustment, lens-free on-chip microscopy can be useful in resource-limited and point-of-care settings. Copyright © 2014, American Association for the Advancement of Science.

  11. Contact lens surface by electron beam

    International Nuclear Information System (INIS)

    Shin, Jung Hyuck; Lee, Suk Ju; Hwang, Kwang Ha; Jeon Jin


    Contact lens materials needs good biocompatibility, high refractive index, high optical transparency, high water content etc. Surface treat method by using plasma and radiation can modify the physical and/or chemical properties of the contact lens surface. Radiation technology such as electron beam irradiation can apply to polymerization reaction and enhance the functionality of the polymer.The purpose of this study is to modify of contact lens surface by using Eb irradiation technology. Electron beam was irradiated to the contact lens surface which was synthesized thermal polymerization method and commercial contact lens to modify physical and chemical properties. Ft-IR, XP, UV-vis spectrophotometer, water content, oxygen trans-metastability were used to characterize the surface state, physicochemical, and optical property of the contact lens treated with Eb. The water content and oxygen transmissibility of the contact lens treated with Eb were increased due to increase in the hydrophilic group such as O-C=O and OH group on the contact lens surface which could be produced by possible reaction between carbon and oxygen during the Eb irradiation. All of the lenses showed the high optical transmittance above 90%. In this case of B/Es, TES, Ti contact lens, the optical transmittance decreased about 5% with increasing Eb dose in the wavelength of UV-B region. The contact lens modified by Eb irradiation could improve the physical properties of the contact lens such as water content and oxygen transmissibility

  12. A little-known 3-lens Catadioptric Camera by Bernard Schmidt (United States)

    Busch, Wolfgang; Ceragioli, Roger C.; Stephani, Walter


    The authors investigate a prototype 3-lens f/1 catadioptric camera, built in 1934 by the famous optician Bernhard Schmidt at the Hamburg-Bergedorf Observatory in Germany, where Schmidt worked before his death in 1935. The prototype is in the observatory's collection of Schmidt artifacts, but its nature was not understood before the authors' recent examination. It is an astronomical camera of a form known as 'Buchroeder-Houghton', consisting of a spherical mirror and a 3-element afocal corrector lens placed at the mirror's center of curvature. The design is named for R.A. Buchroeder and J.L. Houghton who independently published this and related forms of wide-field spherical-lens cameras after 1942. Schmidt died before he could publish his own design. The authors disassembled the prototype and measured its optical parameters. These they present together with a transmission test of the corrector lens. The authors also consider the theoretical performance of the design as built, the theory of Houghton cameras, Schmidt's possible path to his invention, and the place of the prototype in his scientific output.

  13. Thermoluminescent determination of prehistoric heat treatment of chert artifacts

    International Nuclear Information System (INIS)

    Melcher, C.L.; Zimmerman, D.W.


    In recent years archeologists have become interested in the extent to which prehistoric peoples heat-treated chert prior to shaping it into tools. Thermoluminescent determination of the radiation dose accumulated by an artifact since it was formed or last heated provides a simple, reliable test for such heat treatment. This test can be applied to single artifacts without the need for raw source material for comparison. Results on 25 artifacts from four sites indicate that, for many chert sources, color and luster are not useful indicators of heat treatment by prehistoric peoples

  14. Towards a concept of community artifact ecology in HCI?

    DEFF Research Database (Denmark)

    Saad-Sulonen, Joanna; Korsgaard, Henrik

    or workplaces do. This has implications on understanding how to research and design HCI for communities but also on refining the ecological perspective in HCI. We look in particular at examples from preliminary research on a local self-organised urban community and discuss what existing concepts in the ecology......In this paper we introduce the concept of community artifact ecology. We argue that taking a community perspective on the concept of artifact ecologies is relevant in HCI because communities are also dealing with multitudes of artifacts, in ways di↵erent that individuals, organizations...

  15. Lens decenter and tilt measurement by interferogram (United States)

    Hung, Min-Wei; Wu, Wen-Hong; Huang, Kuo-Cheng


    For the recent years, the vigorous development of the electro-optic industry, particularly the digital camera and the cellular phone camera, has placed a larger and larger demand for the optical devices. Among the optical lens, the aspherical optical lens plays the key component because the aspherical lens may provide better imaging quality then the spherical lens does. For the manufacturing reason, the aspherical lens is prone to a decenter or tilt issue with respect to the optical axes of its two surfaces. To measure decenter and tile error specifically would help to obviate the deficient lens, but most of the present measuring method can't provide this function. This paper proposed a new method to specifically measure the decenter and tile of lens by observing the interferogram of each surface. And the corresponding measuring instrument, which contains interferometer and motion stages, was introduced as well.

  16. Artifact in Pediatric Oculomotor Findings during Videonystagmography: A Retrospective Analysis. (United States)

    Doettl, Steven M; Plyler, Patrick N; McCaslin, Devin L


    Accurate measurement of oculomotor function using videonystagmography (VNG) is imperative for diagnosis and management of patients with reported dizziness. The oculomotor evaluation during VNG utilizes video-oculography providing valuable information regarding the central structures and pathways that control eye movements. Artifact may have an effect on the overall validity and reliability of VNG oculomotor tracings and can result from patient and/or recording errors. It is postulated that artifact could occur more frequently in the pediatric population due to both patient and equipment factors. The purpose of this study was to systematically evaluate the occurrence and impact of artifact on saccades, smooth pursuit, and optokinetic (OPK) testing in normal pediatric and adult subjects using commercially available clinical VNG equipment and standard clinical protocols for oculomotor testing. The present study utilized a retrospective analysis of a repeated measures design. Oculomotor results from a total of 62 participants were analyzed. Portions of these data have been presented in a previous research study. Group 1 consisted of twenty-nine 4- to 6-yr-olds with an average age of 4.86 (SD = 0.88) yr. Group 2 consisted of thirty-three 22- to 44-yr-olds with an average age of 25.2 (SD = 5.34) yr. Raw oculomotor recordings were analyzed "offline" by a single masked, trained investigator. Each tracing was evaluated for instances of artifact including eye blinks, eye closure, eyes moving in opposite direction of the target, eye tracking software problems, and overall poor morphology. The number of instances of artifact were noted and recorded for each participant in both groups. Individual eye movements not affected by artifact were included for final analysis. Artifact rejection techniques were also compared. The results indicated increased artifact for the pediatric group for saccade and smooth pursuit testing. Additionally, a significant decrease in instances of

  17. Timing and related artifacts in multidimensional NMR

    International Nuclear Information System (INIS)

    Marion, Dominique


    The information content of multidimensional NMR spectra is limited by the presence of several kinds of artifacts that originate from incorrect timing of evolution periods. The objective of this review is to provide tools for successful implementation of published pulse sequences, in which timing and pulse compensations are often implicit. We will analyze the constraints set by the use of Fourier transformation, the spin precession during rectangular or shaped pulses, the Bloch-Siegert effects due to pulse on other spins and the delay introduced by the filters for the acquisition dimension. A frequency dependent phase correction or an incorrect scaling of the first data point leads to baseline offsets or curvature due to the properties of the Fourier transform. Because any r.f. pulse has a finite length, chemical shift is always active during excitation, flip-back, inversion, and refocusing pulses. Rectangular or selective shaped pulses can be split into three periods: an ideal rotation surrounded by two chemical shift evolution periods, which should be subtracted from the adjacent delays to avoid linear phase correction. Bloch-Siegert effects originate from irradiation at frequencies near those observed in the spectrum and can lead to phase or frequency shifts. They can be minimized by simultaneous irradiation on both sides of the observed spins. In terms of timing, the very end of the pulse sequence the acquisition behaves differently since the data are filtered by either analog or digital means. This additional delay is filter and spectrometer specific and should be tuned to minimize the required phase correction. Combined together, all these adjustments lead to perfectly phased spectra with flat baseline and no peak shifts or distortion. (author)

  18. Chemical Principles Revisited: Artifacts and the Electromotive Series. (United States)

    Mickey, Charles D.


    Reviews chemical information relevant to the study of archeology and specifically to the history of man's use of metals. Gives reasons why most significant artifacts found by archeologists are made of gold instead of iron. (CS)

  19. Cultural Artifact Detection in Long Wave Infrared Imagery.

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Dylan Zachary [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Craven, Julia M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ramon, Eric [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    Detection of cultural artifacts from airborne remotely sensed data is an important task in the context of on-site inspections. Airborne artifact detection can reduce the size of the search area the ground based inspection team must visit, thereby improving the efficiency of the inspection process. This report details two algorithms for detection of cultural artifacts in aerial long wave infrared imagery. The first algorithm creates an explicit model for cultural artifacts, and finds data that fits the model. The second algorithm creates a model of the background and finds data that does not fit the model. Both algorithms are applied to orthomosaic imagery generated as part of the MSFE13 data collection campaign under the spectral technology evaluation project.

  20. Information Content Across Types of Nurse Cognitive Artifacts. (United States)

    Blaz, Jacquelyn W; Doig, Alexa K; Cloyes, Kristin G; Staggers, Nancy


    Acute care nurses commonly use personalized cognitive artifacts to organize information during a shift. The purpose of this content analysis is to compare information content across three formats of cognitive artifacts used by acute care nurses in a medical oncology unit: hand-made free-form, preprinted skeleton, and EHR-generated. Information contained in free-form and skeleton artifacts is more tailored to specific patient context than the NSR. Free-form and skeleton artifacts provide a space for synthesizing information to construct a "story of the patient" that is missing in the NSR. Future design of standardized handoff tools will need to take these differences into account for successful adoption by acute care nurses, including tailoring of information by patient, not just unit type, and allowing a space for nurses to construct a narrative describing the patients "story."

  1. Looking beyond the perfect lens

    International Nuclear Information System (INIS)

    Wee, W H; Pendry, J B


    The holy grail of imaging is the ability to see through anything. From the conservation of energy, we can easily see that to see through a lossy material would require lenses with gain. The aim of this paper therefore is to propose a simple scheme by which we can construct a general perfect lens, with gain-one that can restore both the phases and amplitudes of near and far fields.

  2. Situating Creative Artifacts in Art and Design Research

    Directory of Open Access Journals (Sweden)

    Nithikul Nimkulrat


    Full Text Available This article aims to discuss the position of art and design artifacts, and their creation, in a practice-led research process.  Two creative productions and exhibitions featuring my textile artifacts were intentionally carried out in order to tackle a specific research problem, and these will be examined here as case studies.  These cases cover the production and exhibition of two sets of artworks, named Seeing Paper and Paper World, that were created as part of my completed doctoral research entitled Paperness: Expressive Material inTextile Art from an Artist’s Viewpoint. The study examined the relationship between a physical material and artistic expression in textile art and design.  Both cases exemplify the roles of creative productions and artifacts situated in the process of inquiry.  Throughout a practice-led research process, art and design artifacts can serve as inputs into knowledge production and as outputs for knowledge communication.  As inputs, both art productions and artifacts can be the starting point of a research project from which the research question is formulated.  They can also provide data for analysis from which knowledge is constructed.  Asoutputs, artifacts can indicate whether the research problem requires reformulation, demonstrate the experiential knowledge of the creative process, and strengthen the findings articulated in the written output.  Creative practice in a research context can contribute to generating or enhancing the knowledge which is embedded in the practice and embodied by the practitioner.  This knowledge or insight can be obtained from the artist creating the artifact, the artifact created, the process of making it, and the culture in which it is produced and viewed or used, all taking place at different stages of a research process.

  3. Perspectives on digital computational systems as aesthetic artifacts


    Luísa Ribas


    This paper addresses the study of digital computational systems as aesthetic artifacts seeking to provide instruments for their analysis and critical understanding. What this aim implies is the need to articulate complementary perspectives for considering not only their specificity as digital computational (software-driven) systems, but also the different aesthetic intents that drive the creation of these artifacts, as well as the kinds of experience they propose. This approach entails articu...

  4. A new interpretation of distortion artifacts in sweep measurements

    DEFF Research Database (Denmark)

    Torras Rosell, Antoni; Jacobsen, Finn


    The characterization of acoustical spaces by means of impulse response measurements is often biased by the nonlinear behavior of the loudspeaker used to excite the system under test. In this context the distortion immunity provided by the sweep technique has been investigated. The results show...... that the sweep method can reject a significant amount of distortion artifacts but, in contrast to what is claimed in the literature, it cannot exclude all distortion artifacts from the causal part of the estimated impulse response....

  5. Determiner-Established Deixis to Communicative Artifacts in Pedagogical Text


    Wilson, Shomir; Oberlander, Jon


    Pedagogical materials frequently containdeixis to communicative artifacts such astextual structures (e.g., sections and lists),discourse entities, and illustrations. Byrelating such artifacts to the prose, deixis playsan essential role in structuring the flow ofinformation in informative writing. However,existing language technologies have largelyoverlooked this mechanism. We examineproperties of deixis to communicative artifactsusing a corpus rich in determiner-establishedinstances of the ph...

  6. Reduction of metal artifacts: beam hardening and photon starvation effects (United States)

    Yadava, Girijesh K.; Pal, Debashish; Hsieh, Jiang


    The presence of metal-artifacts in CT imaging can obscure relevant anatomy and interfere with disease diagnosis. The cause and occurrence of metal-artifacts are primarily due to beam hardening, scatter, partial volume and photon starvation; however, the contribution to the artifacts from each of them depends on the type of hardware. A comparison of CT images obtained with different metallic hardware in various applications, along with acquisition and reconstruction parameters, helps understand methods for reducing or overcoming such artifacts. In this work, a metal beam hardening correction (BHC) and a projection-completion based metal artifact reduction (MAR) algorithms were developed, and applied on phantom and clinical CT scans with various metallic implants. Stainless-steel and Titanium were used to model and correct for metal beam hardening effect. In the MAR algorithm, the corrupted projection samples are replaced by the combination of original projections and in-painted data obtained by forward projecting a prior image. The data included spine fixation screws, hip-implants, dental-filling, and body extremity fixations, covering range of clinically used metal implants. Comparison of BHC and MAR on different metallic implants was used to characterize dominant source of the artifacts, and conceivable methods to overcome those. Results of the study indicate that beam hardening could be a dominant source of artifact in many spine and extremity fixations, whereas dental and hip implants could be dominant source of photon starvation. The BHC algorithm could significantly improve image quality in CT scans with metallic screws, whereas MAR algorithm could alleviate artifacts in hip-implants and dentalfillings.

  7. Mitigation of artifacts in rtm with migration kernel decomposition

    KAUST Repository

    Zhan, Ge


    The migration kernel for reverse-time migration (RTM) can be decomposed into four component kernels using Born scattering and migration theory. Each component kernel has a unique physical interpretation and can be interpreted differently. In this paper, we present a generalized diffraction-stack migration approach for reducing RTM artifacts via decomposition of migration kernel. The decomposition leads to an improved understanding of migration artifacts and, therefore, presents us with opportunities for improving the quality of RTM images.


    Directory of Open Access Journals (Sweden)



    Full Text Available A corneal ulcer caused by infection is one of the major causes of blindness worldwide. One of the recent health concerns is the increasing incidence of corneal ulcers associated with contact lens user especially if the users fail to follow specific instruction in using their contact lenses. Risk factors associated with increased risk of contact lens related corneal ulcers are:overnight wear, long duration of continuous wear, lower socio-economic classes, smoking, dry eye and poor hygiene. The presenting symptoms of contact lens related corneal ulcers include eye discomfort, foreign body sensation and lacrimation. More serious symptoms are redness (especially circum-corneal injection, severe pain, photophobia, eye discharge and blurring of vision. The diagnosis is established by a thorough slit lamp microscopic examination with fluorescein staining and corneal scraping for Gram stain and culture of the infective organism. Delay in diagnosing and treatment can cause permanent blindness, therefore an early referral to ophthalmologist and commencing of antimicrobial therapy can prevent visual loss.

  9. Artifact removal in physiological signals--practices and possibilities. (United States)

    Sweeney, Kevin T; Ward, Tomás E; McLoone, Seán F


    The combination of reducing birth rate and increasing life expectancy continues to drive the demographic shift toward an aging population. This, in turn, places an ever-increasing burden on healthcare due to the increasing prevalence of patients with chronic illnesses and the reducing income-generating population base needed to sustain them. The need to urgently address this healthcare "time bomb" has accelerated the growth in ubiquitous, pervasive, distributed healthcare technologies. The current move from hospital-centric healthcare toward in-home health assessment is aimed at alleviating the burden on healthcare professionals, the health care system and caregivers. This shift will also further increase the comfort for the patient. Advances in signal acquisition, data storage and communication provide for the collection of reliable and useful in-home physiological data. Artifacts, arising from environmental, experimental and physiological factors, degrade signal quality and render the affected part of the signal useless. The magnitude and frequency of these artifacts significantly increases when data collection is moved from the clinic into the home. Signal processing advances have brought about significant improvement in artifact removal over the past few years. This paper reviews the physiological signals most likely to be recorded in the home, documenting the artifacts which occur most frequently and which have the largest degrading effect. A detailed analysis of current artifact removal techniques will then be presented. An evaluation of the advantages and disadvantages of each of the proposed artifact detection and removal techniques, with particular application to the personal healthcare domain, is provided.

  10. Artifact removal from EEG signals using adaptive filters in cascade

    International Nuclear Information System (INIS)

    Garces Correa, A; Laciar, E; Patino, H D; Valentinuzzi, M E


    Artifacts in EEG (electroencephalogram) records are caused by various factors, like line interference, EOG (electro-oculogram) and ECG (electrocardiogram). These noise sources increase the difficulty in analyzing the EEG and to obtaining clinical information. For this reason, it is necessary to design specific filters to decrease such artifacts in EEG records. In this paper, a cascade of three adaptive filters based on a least mean squares (LMS) algorithm is proposed. The first one eliminates line interference, the second adaptive filter removes the ECG artifacts and the last one cancels EOG spikes. Each stage uses a finite impulse response (FIR) filter, which adjusts its coefficients to produce an output similar to the artifacts present in the EEG. The proposed cascade adaptive filter was tested in five real EEG records acquired in polysomnographic studies. In all cases, line-frequency, ECG and EOG artifacts were attenuated. It is concluded that the proposed filter reduces the common artifacts present in EEG signals without removing significant information embedded in these records

  11. Analysis of image reconstruction artifacts in structured illumination microscopy (United States)

    Pospíšil, Jakub; Fliegel, Karel; Klíma, Miloš


    Structured Illumination Microscopy (SIM) is a super-resolution technique which enables to enhance the resolution of optical microscopes beyond the diffraction limit. The final super-resolution image quality strongly depends on the performance of SIM image reconstruction. Standard SIM methods require precise knowledge of the illumination pattern and assume the sample to be stationary during the acquisition of illumination patterned images. In the case of imaging live cells, the movements of the cell result in the occurrence of image reconstruction artifacts. To reduce this kind of artifacts the short acquisition time is needed. However, short exposure time causes low signal-to-noise ratio (SNR). Moreover, a drift of the specimen may distort the illumination pattern properties in each image. This issue together with the low SNR makes the estimation of reconstruction parameters a challenging task. Inaccurate assessment of spatial frequency, phase shift or orientation of the illumination pattern leads to incorrect separation and shift of spectral components in Fourier space. This results in unwanted image reconstruction artifacts and hampers the resolution enhancement in practice. In this paper, we analyze possible artifacts in super-resolution images reconstructed using super-resolution SIM technique (SR-SIM). An overview of typical image reconstruction artifact types is presented. Distinguishing image artifacts from newly resolved sample features is essential for future SIM applications in cell biology.

  12. Historical Artifact Collection at the East Tennessee Technology Park

    International Nuclear Information System (INIS)

    Goodpasture, S.T.; Wood, S.K.


    The East Tennessee Technology Park (ETTP) was originally built during World War II as part of the Manhattan Project. Known as the K-25 Site, its primary mission was to enrich uranium for use in atomic weapons. During the Cold War, the site's mission was changed to include the enrichment of uranium for nuclear reactor fuel elements and to recycle spent fuel. In the 1980's, a reduction in the demand for nuclear fuel resulted in the shutdown of the enrichment process and production ceased. The emphasis of the mission for the ETTP was then changed to environmental management and restoration operation. Beginning in the 1990's, re-industrialization (conversion of under-utilized government facilities for use by the private sector) became a major mission at the ETTP. These activities involve cleaning and demolishing facilities. Decommission and demolition (D and D) of facilities at the ETTP or Manhattan Project K-25 Gaseous Diffusion Plant on the U.S. Department of Energy's (DOE) Oak Ridge Reservation (ORR) presented significant challenges complying with the requirements of the National Historic Preservation Act (NHPA) Memorandum of Agreement (MOA) that was negotiated with the stakeholders. Development of a process to identify, record and preserve the artifacts and the cooperation of several agencies and contractors were critical to completing the collection of the artifacts without impacting the D and D project schedule. Additional challenges included contaminated and classified artifacts, entry to facilities with hazardous conditions, schedule pressures and funding for collection and permanent storage. A process was developed to achieve compliance with the requirements of the NHPA. The NHPA requirements and implementing instruments at the ETTP as well as the process developed to preserve significant Manhattan Project era artifacts at the ETTP will be discussed. Implementation of the artifact collection process is also summarized. The challenge of complying with the

  13. Primary intraocular lens implantation for penetrating lens trauma in Africa. (United States)

    Bowman, R J; Yorston, D; Wood, M; Gilbert, C; Foster, A


    This study aimed to audit the surgical strategy of primary posterior chamber intraocular lens implantation for cases of recent penetrating trauma involving the lens in an African population. Retrospective, noncomparative case series. Seventy-two cases are reported, including all patients who underwent primary intraocular lens implantation for traumatic cataract extraction performed within 1 month of injury between 1988 and 1996. Demographic characteristics and follow-up attendance rates are analyzed. Surgical technique and the occurrence of intraoperative and postoperative complications are reported. Visual outcomes are reported with detailed analysis for cases of poor visual outcome. Mean age was 14.3 years (standard deviation = 11.1), 57 (79%) were male and 15 (21%) were female (chi-square = 23.66, P capsule had been breached by the trauma in 27 (38%) cases, and 15 of these required anterior vitrectomy. Capsular fixation of the implant was achieved in 49% of patients, the remainder having sulcus fixation. Intraoperative rupture of the posterior capsule occurred in four cases. The only common postoperative complication was acute fibrinous anterior uveitis, which occurred in 29 (40%) patients, and 32% of patients followed up for at least 6 months required secondary posterior capsulotomy. This was more common in younger patients (chi-square = 4.2, P < 0.05). Corrected postoperative visual acuities were available for 51 patients, of which 71% achieved 20/60 or better visual acuity. Patients 6 years of age or younger were less likely to achieve 20/60 (chi-square = 6.61, P = 0.01). This surgical strategy has proved successful, producing good visual results and causing no sight-threatening complications. Primary posterior capsulotomy may be appropriate for younger patients.

  14. Research on one manual zoom liquid lens (United States)

    Zhao, Cunhua; Shi, Yongpeng; Li, Wenjiao; Li, Congcong


    In liquid zoom lens, the accurate fixed-focus location needs the accurate calculation of focal length. That is to say, the accurate calculation of surface curvature must be obtained. Therefore, the research of their relation in liquid zoom lens becomes extremely important which has a directly theoretical instruction for the design of liquid zoom lenses. In our paper, the relation is studied. A manual liquid lens is reported which has upper and nether components with specificaton Φ12×5mm. The zoom lens is obtained by the upper component circumvolving down into the nether components.

  15. Numerical analyses of planer plasmonic focusing lens (United States)

    Chou, Yen-Yu; Lee, Yeeu-Chang


    The use of polystyrene (PS) sphere lithography has been widely applied in the fabrication of micron and nano structures, due to their low cost and ease of fabrication in large scale applications. This study evaluated the feasibility of plasmonic lens base on metal thin films with nanohole structures fabricated by using PS sphere lithography through three-dimensional (3D) finite difference time domain (FDTD) method. We calculated the intensity profile of lens with various wavelength of incident light, lens size, cutting positions, diameters of nanohole, and periods of nanohole to investigate the geometric parameters influence on the focusing properties of the plasmonic lens.

  16. Exchange of tears under a contact lens is driven by distortions of the contact lens. (United States)

    Maki, Kara L; Ross, David S


    We studied the flow of the post-lens tear film under a soft contact lens to understand how the design parameters of contact lenses can affect ocular health. When a soft contact lens is inserted, the blinking eyelid causes the lens to stretch in order to conform to the shape of the eye. The deformed contact lens acts to assume its un-deformed shape and thus generates a suction pressure in the post-lens tear film. In consequence, the post-lens tear fluid moves; it responds to the suction pressure. The suction pressure may draw in fresh fluid from the edge of the lens, or it may eject fluid there, as the lens reassumes its un-deformed shape. In this article, we develop a mathematical model of the flow of the post-lens tear fluid in response to the mechanical suction pressure of a deformed contact lens. We predict the amount of exchange of fluid exchange under a contact lens and we explore the influence of the eye's shape on the rate of exchange of fluid. © The Author 2014. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email:

  17. Motion Artifact in the MR imaging of temporomandibular disorders

    International Nuclear Information System (INIS)

    Tamamura, Kiyoharu; Miyajima, Hisashi; Nihei, Yoshinobu; Nemoto, Ryuichi; Ohno, Tomoya


    Recently, magnetic resonance imaging (MRI) is indispensable for the diagnosis of temporomandibular disorders (TMD). Motion Artifacts of MRI occur more frequently than in other conventional methods, because it takes a long time to obtain the images. This paper reported on Motion Artifacts on MRI. MRI studies of 232 temporomandibular joints were performed in 116 patients with TMD by using a 0.5-T magnetic resonance (MR) scanner, with spin echo sequence: protondensity-weighted. And we took MRI slices at opening phase and closing phase. So 232 slices were gathered and we evaluated clinically the incidence of Motion Artifacts, that is to say, double and multiple images and other factors. The 103 slices in 56 patients showed Motion Artifacts. There is no significant difference between sexes. By age group, those in their teens were most frequent, followed by those in their fifties, forties, thirties and twenties. Also the same results were obtained for double image and multiple image. Incidence of Motion Artifact was most frequent at the opening phase. There is no significant difference between double and multiple image. (author)

  18. Metal artifact reduction method using metal streaks image subtraction

    International Nuclear Information System (INIS)

    Pua, Rizza D.; Cho, Seung Ryong


    Many studies have been dedicated for metal artifact reduction (MAR); however, the methods are successful to varying degrees depending on situations. Sinogram in-painting, filtering, iterative method are some of the major categories of MAR. Each has its own merits and weaknesses. A combination of these methods or hybrid methods have also been developed to make use of the different benefits of two techniques and minimize the unfavorable results. Our method focuses on the in-paitning approach and a hybrid MAR described by Xia et al. Although in-painting scheme is an effective technique in reducing the primary metal artifacts, a major drawback is the reintroduction of new artifacts that can be caused by an inaccurate interpolation process. Furthermore, combining the segmented metal image to the corrected nonmetal image in the final step of a conventional inpainting approach causes an issue of incorrect metal pixel values. Our proposed method begins with a sinogram in-painting approach and ends with an image-based metal artifact reduction scheme. This work provides a simple, yet effective solution for reducing metal artifacts and acquiring the original metal pixel information. The proposed method demonstrated its effectiveness in a simulation setting. The proposed method showed image quality that is comparable to the standard MAR; however, quantitatively more accurate than the standard MAR

  19. Artifact detection in electrodermal activity using sparse recovery (United States)

    Kelsey, Malia; Palumbo, Richard Vincent; Urbaneja, Alberto; Akcakaya, Murat; Huang, Jeannie; Kleckner, Ian R.; Barrett, Lisa Feldman; Quigley, Karen S.; Sejdic, Ervin; Goodwin, Matthew S.


    Electrodermal Activity (EDA) - a peripheral index of sympathetic nervous system activity - is a primary measure used in psychophysiology. EDA is widely accepted as an indicator of physiological arousal, and it has been shown to reveal when psychologically novel events occur. Traditionally, EDA data is collected in controlled laboratory experiments. However, recent developments in wireless biosensing have led to an increase in out-of-lab studies. This transition to ambulatory data collection has introduced challenges. In particular, artifacts such as wearer motion, changes in temperature, and electrical interference can be misidentified as true EDA responses. The inability to distinguish artifact from signal hinders analyses of ambulatory EDA data. Though manual procedures for identifying and removing EDA artifacts exist, they are time consuming - which is problematic for the types of longitudinal data sets represented in modern ambulatory studies. This manuscript presents a novel technique to automatically identify and remove artifacts in EDA data using curve fitting and sparse recovery methods. Our method was evaluated using labeled data to determine the accuracy of artifact identification. Procedures, results, conclusions, and future directions are presented.

  20. The Visibility of Temporal Artifacts in Stereo 3D Displays

    Directory of Open Access Journals (Sweden)

    Joohwan Kim


    Full Text Available The temporal protocols used in stereoscopic 3D (S3D displays have many parameters that affect the visibility of temporal artifacts. Flicker is visible at low presentation rates. Motion artifacts—judder, edge banding, and edge blur—are salient at low capture rates. Different stereoscopic techniques can introduce distortions in apparent depth. For example, temporal interlacing (i.e., alternating presentation to the two eyes can cause depth distortions for objects moving horizontally across the screen. Spatial interlacing (i.e., presenting information to the two eyes simultaneously, but with alternate pixel rows going to different eyes avoids depth distortions, but causes a reduction in effect spatial resolution. We performed a psychophysical experiment to measure perceptual thresholds for three temporal artifacts in S3D displays: flicker, motion artifacts, and depth distortions. We used a stereoscope consisting of two CRTs running at 200 Hz. A high-precision synchronizer drove the two CRTs thereby allowing us to simulate a wide variety of S3D display protocols accurately. We measured the visibility of the three artifacts while varying presentation rate, capture rate, object contrast, and object velocity. We tested both temporal- and spatial-interlacing protocols. From the results, we developed a perceptual model of artifact visibility in S3D displays.

  1. Ensemble Artifact Design For Context Sensitive Decision Support

    Directory of Open Access Journals (Sweden)

    Shah J Miah


    Full Text Available Although an improvement of design knowledge is an essential goal of design research, current design research predominantly focuses on knowledge concerning the IT artifact (tool design process, rather than a more holistic understanding encompassing the dynamic usage contexts of a technological artifact. Conceptualising a design in context as an “ensemble artifact” (Sein et al., 2011 provides the basis for a more rigorous treatment. This paper describes an IS artifact design framework that has been generated from the development of several practitioner-oriented decision support systems (DSS in which contextual aspects relevant to practitioners’ decision making are considered as integral design themes. We describe five key dimensions of an ensemble artifact design and show their value in designing practitioner-oriented DSS. The features are user centredness, knowledge sharing, situation-specific customisation, reduced model orientation, and practice based secondary design abilities. It is argued that this understanding can contribute to design research knowledge more effectively both to develop dynamic DSS, and by its extensibility to other artifact designs.

  2. [Acanthamoeba isolation from contact lens solution of contact lens wearers without keratitis]. (United States)

    Watanabe, R; Ishibashi, Y; Hommura, S; Ishii, K


    Acanthamoeba keratitis seems to be associated with wearing contact lenses. As controls, we surveyed contact lens wearers without keratitis. Contact lens solutions of 93 persons were examined in order to identify risk factors for contamination by Acanthamoeba. Therefore, the contact lens disinfection system and storage schedules were studied in each case. Acanthamoeba organisms were isolated from 4 specimens (4.3%). The incidence of Acanthamoeba was higher in specimens of soft contact lens solution than in those of hard contact lens solution, and all the Acanthamoeba positive cases had been using tap water.

  3. Primary anterior chamber intraocular lens for the treatment of severe crystalline lens subluxation. (United States)

    Hoffman, Richard S; Fine, I Howard; Packer, Mark


    Subluxated cataractous and clear lenses are commonly treated by limbal or pars plana lensectomy followed by primary or secondary intraocular lens (IOL) implantation. Adjunctive capsular prosthetic devices have facilitated lens removal and IOL centration in these challenging cases but have also added complexity and potential complications to the procedure. Although crystalline lens extraction may be required to clear the visual axis in mild to moderate lens subluxations, we propose insertion of a primary anterior chamber IOL without lens extraction in severe subluxations when the eye is optically aphakic or can be made functionally aphakic following neodymium:YAG laser zonulysis. Two cases demonstrating this approach are presented.

  4. Protection of the eye lens

    International Nuclear Information System (INIS)


    The limit of radiation exposure for eye lens is going to decrease dramatically from 150 to 20 mSv as a transposition into the French law of a CIPR (International Commission for Radiation Protection) directive. Sanitary studies have shown that radiologists are more likely by a factor of 3.8 to get eye lens opacities than the rest of the population. The wearing of protective glasses is recommended and in order to get a better monitoring of the radiation dose new dosimeters have been designed, they can be worn on the glass frame of directly stuck on the skin near the eyes. A study has shown that veterinary surgeons that are accustomed to stay near animals to keep them quiet during radiological exams are prone to receive high doses as well as physicians that use hypnosis to decrease the level of anxiety of their patients during radiological exams. Radiation exposure of radiologists can be mitigated through: the use of protective shields and equipment and the optimization of the dose delivered to the patient. (A.C.)

  5. Correction of ring artifacts in X-ray tomographic images

    DEFF Research Database (Denmark)

    Lyckegaard, Allan; Johnson, G.; Tafforeau, P.


    Ring artifacts are systematic intensity distortions located on concentric circles in reconstructed tomographic X-ray images. When using X-ray tomography to study for instance low-contrast grain boundaries in metals it is crucial to correct for the ring artifacts in the images as they may have...... are separable. The method is implemented in Matlab, it works with very little user interaction and may run in parallel on a cluster if applied to a whole stack of images. The strength and robustness of the method implemented will be demonstrated on three tomographic X-ray data sets: a mono-phase β...... the same intensity level as the grain boundaries and thus make it impossible to perform grain segmentation. This paper describes an implementation of a method for correcting the ring artifacts in tomographic X-ray images of simple objects such as metal samples where the object and the background...

  6. Medical image of the week: DBS polysomnogram artifact

    Directory of Open Access Journals (Sweden)

    Shetty S,


    Full Text Available A 79-year-old man with known Parkinson’s disease and status post deep brain stimulator (DBS implantation underwent an overnight polysomnogram for clinical suspicion of obstructive sleep apnea. Artifact was seen on the polysomnogram recording (Figures 1 & 2. Patient-related electrical artifacts may be seen from devices such as pacemakers, deep brain stimulators and vagal nerve simulators. Abrupt discontinuation of DBS is associated with a high likelihood of worsening of symptoms in patients with Parkinson’s disease (1. Patients with DBS are most commonly programmed in monopolar mode. Bipolar configuration, forms a short electrical dipole that affects a relatively smaller volume of tissue and generates far less artifact, suggesting that this may be an effective option in a Parkinsonian patient with indications for polysomnography (2.

  7. Testing safety commitment in organizations through interpretations of safety artifacts. (United States)

    Luria, Gil; Rafaeli, Anat


    Safety culture relates to injuries and safety incidents in organizations, but is difficult to asses and measure. We describe a preliminary test of assessing an organization's safety culture by examining employee interpretations of organizational safety artifacts (safety signs). We collected data in three organizations using a new safety culture assessment tool that we label the Safety Artifact Interpretation (SAI) scale; we then crossed these data with safety climate and leadership evaluations. SAI were interpreted by employees in accordance with two conceptually distinct themes that are salient in the literature on organizational safety culture: safety compliance and commitment to safety. A significant correlation exists between SAI scores and the organizational safety climate. A similar (though insignificant) relationship was observed between SAI scores and leadership ratings. Employee perceptions and interpretations of safety artifacts can facilitate assessments of safety culture and can ultimately lead to understanding of and improvements in the level of organizational safety.

  8. Color corrected Fresnel lens for solar concentration

    International Nuclear Information System (INIS)

    Kritchman, E.M.


    A new linear convex Fresnel lens with its groove side down is described. The design philosophy is similar to the highly concentrating two focal Fresnel lens but including a correction for chromatic aberration. A solar concentration ratio as high as 80 is achieved. For wide acceptance angles the concentration nears the theoretical maximum. (author)

  9. Modified suturing contact lens for penetrating keratoplasty. (United States)

    Kramer, S G; Stewart, H L


    The authors have previously described a suturing contact lens that protects the corneal endothelium by aiding in the maintenance of the anterior chamber during penetrating keratoplasty. This report describes structural modifications of the suturing contact lens, which improve its stability and effectiveness. An additional configuration for use in corneal lacerations is presented.

  10. Charged black lens in de Sitter space (United States)

    Tomizawa, Shinya


    We obtain a charged black lens solution in the five-dimensional Einstein-Maxwell-Chern-Simons theory with a positive cosmological constant. It is shown that the solution obtained here describes the formation of a black hole with the spatial cross section of a sphere from that of the lens space of L (n ,1 ) in five-dimensional de Sitter space.

  11. Electrostatics Explains the Position-Dependent Effect of G⋅U Wobble Base Pairs on the Affinity of RNA Kissing Complexes. (United States)

    Abi-Ghanem, Josephine; Rabin, Clémence; Porrini, Massimiliano; Dausse, Eric; Toulmé, Jean-Jacques; Gabelica, Valérie


    In the RNA realm, non-Watson-Crick base pairs are abundant and can affect both the RNA 3D structure and its function. Here, we investigated the formation of RNA kissing complexes in which the loop-loop interaction is modulated by non-Watson-Crick pairs. Mass spectrometry, surface plasmon resonance, and UV-melting experiments show that the G⋅U wobble base pair favors kissing complex formation only when placed at specific positions. We tried to rationalize this effect by molecular modeling, including molecular mechanics Poisson-Boltzmann surface area (MMPBSA) thermodynamics calculations and PBSA calculations of the electrostatic potential surfaces. Modeling reveals that the G⋅U stabilization is due to a specific electrostatic environment defined by the base pairs of the entire loop-loop region. The loop is not symmetric, and therefore the identity and position of each base pair matters. Predicting and visualizing the electrostatic environment created by a given sequence can help to design specific kissing complexes with high affinity, for potential therapeutic, nanotechnology or analytical applications. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs.

    Directory of Open Access Journals (Sweden)

    Nikita E Chavarria

    Full Text Available While cytoplasmic tRNA 2-thiolation protein 1 (Tuc1/Ncs6 and ubiquitin-related modifier-1 (Urm1 are important in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U at wobble uridines of tRNAs in eukaryotes, the biocatalytic roles and properties of Ncs6/Tuc1 and its homologs are poorly understood. Here we present the first report of an Ncs6 homolog of archaea (NcsA of Haloferax volcanii that is essential for maintaining cellular pools of thiolated tRNA(LysUUU and for growth at high temperature. When purified from Hfx. volcanii, NcsA was found to be modified at Lys204 by isopeptide linkage to polymeric chains of the ubiquitin-fold protein SAMP2. The ubiquitin-activating E1 enzyme homolog of archaea (UbaA was required for this covalent modification. Non-covalent protein partners that specifically associated with NcsA were also identified including UbaA, SAMP2, proteasome activating nucleotidase (PAN-A/1, translation elongation factor aEF-1α and a β-CASP ribonuclease homolog of the archaeal cleavage and polyadenylation specificity factor 1 family (aCPSF1. Together, our study reveals that NcsA is essential for growth at high temperature, required for formation of thiolated tRNA(LysUUU and intimately linked to homologs of ubiquitin-proteasome, translation and RNA processing systems.

  13. Contact Lens Use in the Civil Airman Population

    National Research Council Canada - National Science Library

    Nakagawara, Van


    ...) aeromedical certificate. Although contact lens technology has advanced dramatically in recent years, the aviation environment may still have adverse effects on contact lens performance in some flight situations...

  14. Corrected electrostatic lens systems for ion beams

    International Nuclear Information System (INIS)

    Dalgish, R.L.


    Recent work in our laboratory has introduced a new class of electrostatic focus forming element for beams, the ELCO lens. It compares favourably with the electrostatic and magnetic quadrupole elements conventionally used for microbeam formation. The ELCO lens does however have disadvantages associated with apertures and alignment. We have continued with the development of ion beam lenses and have evolved a further class of lens element which eliminates aperture and alignment problems. This new element can be combined like optical lenses into an aberration corrected system. Experimental measurement on the basic lens element has confirmed mathematical analysis of ion trajectories through the element. This mathematical analysis predicts that the basic element can be combined into a corrected lens system for, either: (1) high resolution microprobe formation with intrinsic rastering ability, the spot size limited only by the beam properties; or (2) high quality image formation with large magnification/demagnification ratio and wide angular aperture. (orig.)

  15. Motion characterization scheme to minimize motion artifacts in intravital microscopy (United States)

    Lee, Sungon; Courties, Gabriel; Nahrendorf, Matthias; Weissleder, Ralph; Vinegoni, Claudio


    Respiratory- and cardiac-induced motion artifacts pose a major challenge for in vivo optical imaging, limiting the temporal and spatial imaging resolution in fluorescence laser scanning microscopy. Here, we present an imaging platform developed for in vivo characterization of physiologically induced axial motion. The motion characterization system can be straightforwardly implemented on any conventional laser scanning microscope and can be used to evaluate the effectiveness of different motion stabilization schemes. This method is particularly useful to improve the design of novel tissue stabilizers and to facilitate stabilizer positioning in real time, therefore facilitating optimal tissue immobilization and minimizing motion induced artifacts.

  16. Importance of correct interpretation of postmortem artifacts in medicolegal autopsies. (United States)

    Mirza, F H; Makhdoom, P A


    To study whether various injuries labelled as antemortem are in fact postmortem artifacts. 780 postmortems conducted in mortuary of S.M.C. Karachi from 1-1-95 to 20-9-95. Out of 780 autopsies, 229 showed postmortem artifacts which included decomposition in 78, animal and insects producing changes in 45, injuries due to rough handling in 40, breaking of rigor mortis and shifting of postmortem lividity during transportation in 37, iatrogenic fracture of skull during opening in 15, fractured ribs during resuscitation after death in 8 and exhumation producing fractures of bones in 6 bodies.

  17. EEG Artifact Removal Using a Wavelet Neural Network (United States)

    Nguyen, Hoang-Anh T.; Musson, John; Li, Jiang; McKenzie, Frederick; Zhang, Guangfan; Xu, Roger; Richey, Carl; Schnell, Tom


    !n this paper we developed a wavelet neural network. (WNN) algorithm for Electroencephalogram (EEG) artifact removal without electrooculographic (EOG) recordings. The algorithm combines the universal approximation characteristics of neural network and the time/frequency property of wavelet. We. compared the WNN algorithm with .the ICA technique ,and a wavelet thresholding method, which was realized by using the Stein's unbiased risk estimate (SURE) with an adaptive gradient-based optimal threshold. Experimental results on a driving test data set show that WNN can remove EEG artifacts effectively without diminishing useful EEG information even for very noisy data.

  18. Metal artifacts in computed tomography for radiation therapy planning: dosimetric effects and impact of metal artifact reduction (United States)

    Giantsoudi, Drosoula; De Man, Bruno; Verburg, Joost; Trofimov, Alexei; Jin, Yannan; Wang, Ge; Gjesteby, Lars; Paganetti, Harald


    A significant and increasing number of patients receiving radiation therapy present with metal objects close to, or even within, the treatment area, resulting in artifacts in computed tomography (CT) imaging, which is the most commonly used imaging method for treatment planning in radiation therapy. In the presence of metal implants, such as dental fillings in treatment of head-and-neck tumors, spinal stabilization implants in spinal or paraspinal treatment or hip replacements in prostate cancer treatments, the extreme photon absorption by the metal object leads to prominent image artifacts. Although current CT scanners include a series of correction steps for beam hardening, scattered radiation and noisy measurements, when metal implants exist within or close to the treatment area, these corrections do not suffice. CT metal artifacts affect negatively the treatment planning of radiation therapy either by causing difficulties to delineate the target volume or by reducing the dose calculation accuracy. Various metal artifact reduction (MAR) methods have been explored in terms of improvement of organ delineation and dose calculation in radiation therapy treatment planning, depending on the type of radiation treatment and location of the metal implant and treatment site. Including a brief description of the available CT MAR methods that have been applied in radiation therapy, this article attempts to provide a comprehensive review on the dosimetric effect of the presence of CT metal artifacts in treatment planning, as reported in the literature, and the potential improvement suggested by different MAR approaches. The impact of artifacts on the treatment planning and delivery accuracy is discussed in the context of different modalities, such as photon external beam, brachytherapy and particle therapy, as well as by type and location of metal implants.

  19. Investigation of lens morphology and mechanical characteristics of lens capsule and lens nucleus in patients with agerelated and diabetic cataract

    Directory of Open Access Journals (Sweden)

    A. S. Tishkova


    Full Text Available Purpose: To investigate the influence of carbohydrate metabolism on the structure and mechanical properties of the lens capsule and nucleus.Methods: Human lens pathology was studied in different forms of cataract. 220 patients with a cataract (220 eyes were included in this study. Morphological, immunohystological and immunocytochemical investigations of lens substance (antibodies to a- (a-А and a-В, b-, g- crystallines, spectroscopic analyses of smears and morphometric analyses of slices, investigation of lens morphology and mechanical caracteristics of lens capsule and lens nucleus were performed.Results: The capsule of the lens in patients with senile cataract contains more Na+, Cl-. The capsule of the lens in patients with senile cataract contains more Ca2+, O. Mechanical strength of the capsule in the case of diabetes mellitus was lower comparatively with senile cataract in the same age groups. More significant expression of a-В and b-crystallines was found in patients with diabetes mellitus comparatively with patients with age-related cataract. Morphological features were founded in patients with cortical and nuclear forms of senile cataract and the diabetic cataract.Conclusion: During surgery (ultrasonic microcoaxial phacoemulsification the equivalent of ultrasound was recorded. Lower density of the lens nucleus of patients with diabetes mellitus made it possible to use lower energy parameters. Using the torsion ultrasound in those cases allowed us to decrease the influence of ultrasound on eye tissues and reduce the time of achieving the maximum BCVA in the postsurgical period.

  20. Investigation of lens morphology and mechanical characteristics of lens capsule and lens nucleus in patients with agerelated and diabetic cataract

    Directory of Open Access Journals (Sweden)

    A. S. Tishkova


    Full Text Available Purpose: To investigate the influence of carbohydrate metabolism on the structure and mechanical properties of the lens capsule and nucleus.Methods: Human lens pathology was studied in different forms of cataract. 220 patients with a cataract (220 eyes were included in this study. Morphological, immunohystological and immunocytochemical investigations of lens substance (antibodies to a- (a-А and a-В, b-, g- crystallines, spectroscopic analyses of smears and morphometric analyses of slices, investigation of lens morphology and mechanical caracteristics of lens capsule and lens nucleus were performed.Results: The capsule of the lens in patients with senile cataract contains more Na+, Cl-. The capsule of the lens in patients with senile cataract contains more Ca2+, O. Mechanical strength of the capsule in the case of diabetes mellitus was lower comparatively with senile cataract in the same age groups. More significant expression of a-В and b-crystallines was found in patients with diabetes mellitus comparatively with patients with age-related cataract. Morphological features were founded in patients with cortical and nuclear forms of senile cataract and the diabetic cataract.Conclusion: During surgery (ultrasonic microcoaxial phacoemulsification the equivalent of ultrasound was recorded. Lower density of the lens nucleus of patients with diabetes mellitus made it possible to use lower energy parameters. Using the torsion ultrasound in those cases allowed us to decrease the influence of ultrasound on eye tissues and reduce the time of achieving the maximum BCVA in the postsurgical period.

  1. Cuba Through A New Lens

    Directory of Open Access Journals (Sweden)

    Jean Stubbs


    Full Text Available [First paragraph] The Origins of the Cuban Revolution Reconsidered. Samuel Farber. Chapel Hill: University of North Carolina Press, 2006. x + 212 pp. (Paper US$ 19.95 Cuba: A New History. Ric hard Gott . New Haven: Yale University Press, 2005. xii + 384 pp. (Paper US$ 17.00 Havana: The Making of Cuban Culture. Antoni Kapcia. Oxford: Berg Publishers, 2005. xx + 236 pp. (Paper US$ 24.95 Richard Gott, Antoni Kapcia, and Samuel Farber each approach Cuba through a new lens. Gott does so by providing a broad-sweep history of Cuba, which is epic in scope, attaches importance to social as much as political and economic history, and blends scholarship with flair. Kapcia homes in on Havana as the locus for Cuban culture, whereby cultural history becomes the trope for exploring not only the city but also Cuban national identity. Farber revisits his own and others’ interpretations of the origins of the Cuban Revolution.

  2. Radiation studies in Lens culinaris

    International Nuclear Information System (INIS)

    Sinha, S.S.N.


    Estimation of chromosomal aberrations in flowers of Lens culinaris according to their sequence of development in the plants at 4, 8 and 12 Kr in the M 1 generation, showed that the later formed flowers had smaller percentages of cells with aberrations than those developed earlier. It is suggested that this may be the result of competition between more damaged and less damaged cells during the development of the shoot. There is consequently a decrease of sterility in successive flowers. The numbers of karyotypes taking part in the formation of lower and uppermost flowers were estimated cytologically at 4, 8 and 12 Kr. It was found that more karyotypes were involved in the formation of the lower flowers than in the upper ones. It appeared that at lower doses larger numbers of karyotypes were taking part in the formation of the chimaera than at higher doses. (auth.)

  3. Microbial contamination of contact lens storage cases and domestic tap water of contact lens wearers. (United States)

    Üstüntürk, Miray; Zeybek, Zuhal


    Contact lenses have been widely used as an alternative to spectacles both in developed and developing countries. However, under certain circumstances, adverse responses can occur during contact lens wear and several microorganisms--including bacteria, fungi, and free living amoebae--can cause several eye infections in wearers. Extended wear of contact lenses is the major risk factor of eye infections such as microbial keratitis, besides contaminated contact lens storage case, contaminated lens care solutions, and inaccurate contact lens handling. In this study, we collected contact lens storage case and domestic tap water samples from 50 asymptomatic contact lens wearers. We determined that total aerobic mesophilic bacteria were isolated in 45 (90 %), Gram negative rod bacteria were isolated in 20 (40 %), Pseudomonas spp. were isolated in 2 (4 %) and fungi were isolated in 18 (36 %) out of 50 contact lens storage cases. Free living amoebae were not detected in investigated contact lens storage cases. At the same time, out of 50, total aerobic mesophilic bacteria were isolated in 34 (68 %), fungi were isolated in 15 (30 %) and free living amoebae were isolated in 15 (30 %) domestic tap water samples. No Gram-negative rod bacteria and Pseudomonas spp. were detected in investigated water samples. Two contact lens case samples and two tap water samples were excluded from the analysis for Pseudomonas spp. for technical reasons. According to our findings, inadequate contact lens maintenance during lens wear may result in the contamination of contact lens storage cases. This situation can lead to severe eye infections in contact lens wearers over time.

  4. Design of educational artifacts as support to learning process. (United States)

    Resende, Adson Eduardo; Vasconcelos, Flávio Henrique


    The aim of this paper is to identify utilization schemes developed by students and teachers in their interaction with educational workstations in the electronic measurement and instrumentation laboratory at the Department of Electrical Engineering in the Federal University of Minas Gerais (UFMG), Brazil. After that, these schemes were used to design a new workstation. For this, it was important to bear in mind that the mentioned artifacts contain two key characteristics: (1) one from the designers themselves, resulting from their experience and their technical knowledge of what they are designing and (2) the experience from users and the means through which they take advantage of and develop these artifacts, in turn rendering them appropriate to perform the proposed task - the utilization schemes developed in the process of mediation between the user and the artifact. The satisfactory fusion of these two points makes these artifacts a functional unit - the instruments. This research aims to demonstrate that identifying the utilization schemes by taking advantage of user experience and incorporating this within the design, facilitates its appropriation and, consequently, its efficiency as an instrument of learning.

  5. Coevolution of variability models and related software artifacts

    DEFF Research Database (Denmark)

    Passos, Leonardo; Teixeira, Leopoldo; Dinztner, Nicolas


    models coevolve with other artifact types, we study a large and complex real-world variant-rich software system: the Linux kernel. Specifically, we extract variability-coevolution patterns capturing changes in the variability model of the Linux kernel with subsequent changes in Makefiles and C source...

  6. Assessment of intraoral image artifacts related to photostimulable ...

    African Journals Online (AJOL)

    Assessment of intraoral image artifacts related to photostimulable phosphor plates in a dentomaxillofacial radiology department. ... Of these, 2008 were of adult patients and 336 were of pediatric patients. While movement of the phosphor plate in the disposable pocket was the most common cause of the observed image ...

  7. Artifacts as Stories: Understanding Families, Digital Literacies, and Storied Lives (United States)

    Lewis Ellison, Tisha


    This column focuses on the interactions during family and group conversation circles that not only helped participants talk about personal, emotional, and social issues in their digital stories but also helped them make sense of artifacts and the meanings that stories carry in shared spaces and practices. This work adds to the bourgeoning…

  8. Soft tissue artifact in canine kinematic gait analysis

    NARCIS (Netherlands)

    Schwencke, M.; Smolders, L.A.; Bergknut, N.; Gustas, P.; Meij, B.P.; Hazewinkel, H.A.W.


    Vet Surg. 2012 Oct;41(7):829-37. doi: 10.1111/j.1532-950X.2012.01021.x. Soft tissue artifact in canine kinematic gait analysis. Schwencke M, Smolders LA, Bergknut N, Gustås P, Meij BP, Hazewinkel HA. Source Department of Clinical Sciences of Companion Animals,, Faculty of Veterinary Medicine,

  9. Automatic correction of dental artifacts in PET/MRI

    DEFF Research Database (Denmark)

    Ladefoged, Claes N.; Andersen, Flemming L.; Keller, Sune


    A challenge when using current magnetic resonance (MR)-based attenuation correction in positron emission tomography/MR imaging (PET/MRI) is that the MRIs can have a signal void around the dental fillings that is segmented as artificial air-regions in the attenuation map. For artifacts connected t...

  10. 77 FR 40914 - Arts and Artifacts Indemnity Panel Advisory Committee (United States)


    ... ARTS AND THE HUMANITIES Arts and Artifacts Indemnity Panel Advisory Committee AGENCY: Federal Council on the Arts and the Humanities, National Endowment for the Humanities, National Foundation on the Arts and the Humanities. ACTION: Notice of meeting. SUMMARY: Pursuant to section 10(a)(2) of the...

  11. 77 FR 64146 - Arts and Artifacts Indemnity Panel Advisory Committee (United States)


    ... ARTS AND THE HUMANITIES Arts and Artifacts Indemnity Panel Advisory Committee AGENCY: Federal Council on the Arts and the Humanities, National Endowment for the Humanities. ACTION: Notice of meeting... hereby given that the Federal Council on the Arts and the Humanities will hold a meeting of the Arts and...

  12. 78 FR 4878 - Arts and Artifacts Indemnity Panel Advisory Committee (United States)


    ... ARTS AND THE HUMANITIES Arts and Artifacts Indemnity Panel Advisory Committee AGENCY: Federal Council on the Arts and the Humanities; National Endowment for the Humanities. ACTION: Notice of meeting... hereby given that the Federal Council on the Arts and the Humanities will hold a meeting of the Arts and...

  13. quantification of rain quantification of rain induced artifacts on digital

    African Journals Online (AJOL)


    3DEPARTMENT OF PHYSICS, OSUN STATE UNIVERSITY,OSOGBO, OSUN STATE. NIGERIA. 5 KING FAHD ... The presence of artifacts on the high definition television (TV) content and the eventual loss of the digital TV signals to rain is still a ... 4, October 2015 803 a short period of time over a little coverage area, and.

  14. Science Teachers Sharing Artifacts from Practice like Students’ Tablet Productions

    DEFF Research Database (Denmark)

    Nielsen, Birgitte Lund

    to support the success of integrating technology. Experiences from a large-scale, long-term TPD project for primary and secondary science teachers supporting the teachers in trying out innovative practices and new ICT tools in own classes, and in sharing artifacts from these trials in teacher networks...

  15. Total Variation-Based Reduction of Streak Artifacts, Ring Artifacts and Noise in 3D Reconstruction from Optical Projection Tomography

    Czech Academy of Sciences Publication Activity Database

    Michálek, Jan


    Roč. 21, č. 6 (2015), s. 1602-1615 ISSN 1431-9276 R&D Projects: GA MŠk(CZ) LH13028; GA ČR(CZ) GA13-12412S Institutional support: RVO:67985823 Keywords : optical projection tomography * microscopy * artifacts * total variation * data mismatch Subject RIV: EA - Cell Biology Impact factor: 1.730, year: 2015

  16. Contact lens compliance among a group of young, university-based lens users in South India. (United States)

    Noushad, Babu; Saoji, Yeshwant; Bhakat, Premjit; Thomas, Jyothi


    To investigate the rate of compliance with the soft contact lens care and maintenance procedures with a focus on contact lens wearing habits, cleaning and disinfecting procedures, and maintenance of lens care accessories in a group of young, university-based contact lens wearers Two hundred and sixteen young soft contact lens wearers with an age range of 18-22 years were selected conveniently from the student population of Manipal University, Manipal, India. After receiving informed consent from the participants, their level of compliance with contact lenses was assessed using a questionnaire. The mean (±SD) age of the participants was 21.86±2.35 years. Out of 216 subjects, only 34% of the lens users were identified to be compliant with the least level of compliance observed in the maintenance of lens care accessories. Conventional users showed significantly (p=0.001) better level of compliance compared to disposable wearers and so did the users who acquired their lenses from clinicians (p=0.001) compared to over-the-counter lens receipt. The gender (p=0.496) and years of experience in contact lens use (p=0.142) did not show any statistically significant difference in the level of compliance. This study demonstrated that non-compliance with lens care procedures among a group of young, university-based soft contact lens wearers is common. The results indicated that all subjects had some degree of non-compliance and the least level of compliance observed in the care of lens accessories.

  17. Tear film physiology and contact lens wear. II. Contact lens-tear film interaction. (United States)

    Holly, F J


    The successful fitting of contact lenses requires the practitioner to take into account many properties of the specific lens type used but the practitioner must also understand patient factors including tear properties, use of appropriate solutions, procedures for lens cleaning, and efficiency of blinking. Selection of appropriate patients, selection of lens type, proper fitting, good maintenance, and training and monitoring of patients increase the probability of achieving success.

  18. A model-based analysis of a simplified beam-specific dose output in proton therapy with a single-ring wobbling system. (United States)

    Kase, Yuki; Yamashita, Haruo; Numano, Masumi; Sakama, Makoto; Mizota, Manabu; Maeda, Yoshikazu; Tameshige, Yuji; Murayama, Shigeyuki


    In radiation therapy, it is necessary to preset a monitor unit in an irradiation control system to deliver a prescribed absolute dose to a reference point in the planning target volume. The purpose of this study was to develop a model-based monitor unit calculation method for proton-beam therapy with a single-ring wobbling system. The absorbed dose at a calibration point per monitor unit had been measured for each beam-specific measurement condition without a patient-specific collimator or range compensator before proton therapeutic irradiation at Shizuoka Cancer Center. In this paper, we propose a simplified dose output model to obtain the output ratio between a beam-specific dose and a reference field dose, from which a monitor unit for the proton treatment could be derived without beam-specific measurements. The model parameters were determined to fit some typical data measured in a proton treatment room, called a Gantry 1 course. Then, the model calculation was compared with 5456 dose output ratios that had been measured for 150-, 190- and 220 MeV therapeutic proton beams in two treatment rooms over the past decade. The mean value and standard deviation of the difference between the measurement and the model calculation were respectively 0.00% and 0.27% for the Gantry 1 course, and -0.25% and 0.35% for the Gantry 2 course. The model calculation was in good agreement with the measured beam-specific doses, within 1%, except for conditions less frequently used for treatment. The small variation for the various beam conditions shows the high long-term reproducibility of the measurement and high degree of compatibility of the two treatment rooms. Therefore, the model was expected to assure the setting value of the dose monitor for treatment, to save the effort required for beam-specific measurement, and to predict the dose output for new beam conditions in the future.

  19. Effects of artifact removal on cone-beam computed tomography images

    Directory of Open Access Journals (Sweden)

    Hooriyeh Bashizade Fakhar


    Conclusion: Applying artifact removal does not affect the visibility of large anatomical structures and linear bone measurements, but delicate structures such as lamina dura may become less clear after artifact removal.

  20. Placement of a crystalline lens and intraocular lens: Retinal image quality. (United States)

    Siedlecki, Damian; Nowak, Jerzy; Zajac, Marek


    The influence of changes of both crystalline lens and intraocular lens (IOL) misalignment on the retinal image quality was investigated. The optical model of the eye used in investigations was the Liou-Brennan model, which is commonly considered as one of the most anatomically accurate. The original crystalline lens from this model was replaced with an IOL, made of rigid polymethylmethacrylate, in a way that recommend obligatory procedures. The modifications that were made both for crystalline lens and IOL were the longitudinal, the transversal, and the angular displacement.

  1. Restoring lens capsule integrity enhances lens regeneration in New Zealand albino rabbits and cats. (United States)

    Gwon, A; Gruber, L J; Mantras, C


    In studies conducted by numerous investigators for 150 years, lenses regenerated following endocapsular lens extraction in New Zealand albino rabbits have been irregular in shape, appearing primarily doughnut-shaped as a result of lack of lens growth at the site of the anterior capsulotomy and its adhesion to the posterior capsule. In the present study, we restored the lens capsule integrity by inserting a collagen patch at the time of surgery to seal the anterior capsulotomy and to improve the shape and structure of the regenerated lenses. We then filled the capsule bag with air to prevent adhesions between the anterior and posterior capsule and maintain capsule tautness and shape. Lens regeneration was first noted as early as one to two weeks. Regenerated lens filled approximately 50% of the capsule bag at two weeks and 100% by five weeks. Subsequent growth was in the anterior-posterior direction and measured by A-scan biometry. Lens thickness increased by 0.3 mm per month. The regenerated lenses were spherical with normal cortical structure and a nuclear opacity. In conclusion, restoration of lens capsular integrity with a collagen patch following endocapsular lens extraction enhanced the shape, structure, and growth rate of the regenerated lenses. In addition, lens regeneration was shown to occur in two cats.

  2. Development of Fresnel lens for improvement of rear visibility; Shikai kojo Fresnel lens no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Iwamoto, K.; Sanada, C.; Tsukino, M. [Nissan Motor Co. Ltd., Tokyo (Japan)


    Fresnel lenses have been widely used to increase the visual field around vehicles for drivers. However, internal reflection in these lenses has been an obstacle in producing dear images. This internal glow is generated by incident light from an unexpected direction reflecting on the non-lens surface or radiating from the non-lens surface of the Fresnel lens. The cause of internal glow has been made dear combining louver film with the lens. The newly developed technology removes obstacles in producing dear images by reducing internal glow. 7 figs.

  3. Night Vision Goggles Objectives Lens Focusing Methodology

    National Research Council Canada - National Science Library

    Pinkus, Alan; Task, H. L


    ...: interpupillary distance, tilt, eye relief, height, eyepiece and objective lens focus. Currently, aircrew use a Hoffman 20/20 test unit to pre-focus their NVG objective lenses at optical infinity before boarding their aircraft...

  4. Role of Aquaporin 0 in lens biomechanics

    Energy Technology Data Exchange (ETDEWEB)

    Sindhu Kumari, S.; Gupta, Neha [Physiology and Biophysics, Stony Brook University, Stony Brook, NY (United States); Shiels, Alan [Washington University School of Medicine, St. Louis, MO (United States); FitzGerald, Paul G. [Cell Biology and Human Anatomy, School of Medicine, University of California, Davis, CA (United States); Menon, Anil G. [University of Cincinnati College of Medicine, Cincinnati, OH (United States); Mathias, Richard T. [Physiology and Biophysics, Stony Brook University, Stony Brook, NY (United States); SUNY Eye Institute, NY (United States); Varadaraj, Kulandaiappan, E-mail: [Physiology and Biophysics, Stony Brook University, Stony Brook, NY (United States); SUNY Eye Institute, NY (United States)


    Maintenance of proper biomechanics of the eye lens is important for its structural integrity and for the process of accommodation to focus near and far objects. Several studies have shown that specialized cytoskeletal systems such as the beaded filament (BF) and spectrin-actin networks contribute to mammalian lens biomechanics; mutations or deletion in these proteins alters lens biomechanics. Aquaporin 0 (AQP0), which constitutes ∼45% of the total membrane proteins of lens fiber cells, has been shown to function as a water channel and a structural cell-to-cell adhesion (CTCA) protein. Our recent ex vivo study on AQP0 knockout (AQP0 KO) mouse lenses showed the CTCA function of AQP0 could be crucial for establishing the refractive index gradient. However, biomechanical studies on the role of AQP0 are lacking. The present investigation used wild type (WT), AQP5 KO (AQP5{sup −/−}), AQP0 KO (heterozygous KO: AQP0{sup +/−}; homozygous KO: AQP0{sup −/−}; all in C57BL/6J) and WT-FVB/N mouse lenses to learn more about the role of fiber cell AQPs in lens biomechanics. Electron microscopic images exhibited decreases in lens fiber cell compaction and increases in extracellular space due to deletion of even one allele of AQP0. Biomechanical assay revealed that loss of one or both alleles of AQP0 caused a significant reduction in the compressive load-bearing capacity of the lenses compared to WT lenses. Conversely, loss of AQP5 did not alter the lens load-bearing ability. Compressive load-bearing at the suture area of AQP0{sup +/−} lenses showed easy separation while WT lens suture remained intact. These data from KO mouse lenses in conjunction with previous studies on lens-specific BF proteins (CP49 and filensin) suggest that AQP0 and BF proteins could act co-operatively in establishing normal lens biomechanics. We hypothesize that AQP0, with its prolific expression at the fiber cell membrane, could provide anchorage for cytoskeletal structures like BFs and

  5. Quantitative evaluation of artifact removal in real magnetoencephalogram signals with blind source separation


    Escudero, Javier; Hornero, Roberto; Fernandez Perez, Alvaro; Abasolo, Daniel


    The magnetoencephalogram (MEG) is contaminated with undesired signals, which are called artifacts. Some of the most important ones are the cardiac and the ocular artifacts (CA and OA, respectively), and the power line noise (PLN). Blind source separation (BSS) has been used to reduce the influence of the artifacts in the data. There is a plethora of BSS-based artifact removal approaches, but few comparative analyses. In this study, MEG background activity from 26 subjects was processed with f...

  6. Contractual considerations in contact lens practice. (United States)

    Classé, J G


    The use of forms in contact lens practice can save time, promote patient education, and reduce the opportunity for legal or economic disputes. The most commonly employed forms are those for contact lens fitting agreements, instructions for care and maintenance of lenses, prepaid service agreements, clinical investigations of investigatory lenses or solutions, and for extended wear patients. Sample forms are utilized for purposes of illustration.

  7. Evolution and the Calcite Eye Lens


    Williams, Vernon L.


    Calcite is a uniaxial, birefringent crystal, which in its optically transparent form, has been used for animal eye lenses, the trilobite being one such animal. Because of the calcite birefringence there is a difficulty in using calcite as a lens. When the propagation direction of incoming light is not exactly on the c-axis, the mages blur. In this paper, calcite blurring is evaluated, and the non-blurring by a crystallin eye lens is compared to a calcite one.

  8. Acute lens-induced glaucomas: A review

    Directory of Open Access Journals (Sweden)

    Syed Shoeb Ahmad


    Full Text Available Lens-induced factors are important and common mechanisms causing acute elevation of intraocular pressure. While in most cases, the diagnosis and management are straight-forward, in others it is difficult and can lead to improper procedures, complications and poor visual outcomes. This review was done with the aim of studying the various types of lens-induced glaucomas, classifying them in an easy way to understand manner, their clinical features, current management and future possibilities.

  9. Acoustic lens for capacitive micromachined ultrasonic transducers (United States)

    Chang, Chienliu; Firouzi, Kamyar; Park, Kwan Kyu; Sarioglu, Ali Fatih; Nikoozadeh, Amin; Yoon, Hyo-Seon; Vaithilingam, Srikant; Carver, Thomas; Khuri-Yakub, Butrus T.


    Capacitive micromachined ultrasonic transducers (CMUTs) have great potential to compete with traditional piezoelectric transducers in therapeutic ultrasound applications. In this paper we have designed, fabricated and developed an acoustic lens formed on the CMUT to mechanically focus ultrasound. The acoustic lens was designed based on the paraxial theory and made of silicone rubber for acoustic impedance matching and encapsulation. The CMUT was fabricated based on the local oxidation of silicon (LOCOS) and fusion-bonding. The fabricated CMUT was verified to behave like an electromechanical resonator in air and exhibited wideband response with a center frequency of 2.2 MHz in immersion. The fabrication for the acoustic lens contained two consecutive mold castings and directly formed on the surface of the CMUT. Applied with ac burst input voltages at the center frequency, the CMUT with the acoustic lens generated an output pressure of 1.89 MPa (peak-to-peak) at the focal point with an effective focal gain of 3.43 in immersion. Compared to the same CMUT without a lens, the CMUT with the acoustic lens demonstrated the ability to successfully focus ultrasound and provided a viable solution to the miniaturization of the multi-modality forward-looking endoscopes without electrical focusing.

  10. Acoustic lens for capacitive micromachined ultrasonic transducers

    International Nuclear Information System (INIS)

    Chang, Chienliu; Firouzi, Kamyar; Sarioglu, Ali Fatih; Nikoozadeh, Amin; Yoon, Hyo-Seon; Vaithilingam, Srikant; Carver, Thomas; Khuri-Yakub, Butrus T; Kyu Park, Kwan


    Capacitive micromachined ultrasonic transducers (CMUTs) have great potential to compete with traditional piezoelectric transducers in therapeutic ultrasound applications. In this paper we have designed, fabricated and developed an acoustic lens formed on the CMUT to mechanically focus ultrasound. The acoustic lens was designed based on the paraxial theory and made of silicone rubber for acoustic impedance matching and encapsulation. The CMUT was fabricated based on the local oxidation of silicon (LOCOS) and fusion-bonding. The fabricated CMUT was verified to behave like an electromechanical resonator in air and exhibited wideband response with a center frequency of 2.2 MHz in immersion. The fabrication for the acoustic lens contained two consecutive mold castings and directly formed on the surface of the CMUT. Applied with ac burst input voltages at the center frequency, the CMUT with the acoustic lens generated an output pressure of 1.89 MPa (peak-to-peak) at the focal point with an effective focal gain of 3.43 in immersion. Compared to the same CMUT without a lens, the CMUT with the acoustic lens demonstrated the ability to successfully focus ultrasound and provided a viable solution to the miniaturization of the multi-modality forward-looking endoscopes without electrical focusing. (paper)

  11. LENS: Science Scope and Development Stages (United States)

    Vogelaar, R. Bruce


    The Low-Energy Neutrino Spectroscopy (LENS) experiment will resolve the solar metallicity question via measurement of the CNO neutrino flux, as well as test the predicted equivalence of solar luminosity as measured by photon versus neutrinos. The LENS detector uses charged-current interaction of neutrinos on Indium-115 (loaded in a scintillator, InLS) to reveal the complete solar neutrino spectrum. LENS's optically segmented 3D lattice geometry achieves precise time and spatial resolution and unprecedented background rejection and sensitivity for low-energy neutrino events. This first-of-a-kind lattice design is also suited for a range of other applications where high segmentation and large light collection are required (eg: sterile neutrinos with sources, double beta decay, and surface detection of reactor neutrinos). The physics scope, detector design, and logic driving the microLENS and miniLENS prototyping stages will be presented. The collaboration is actively running programs; building, operating, developing, and simulating these prototypes using the Kimballton Underground Research Facility (KURF). New members are welcome to the LENS Collaboration, and interested parties should contact R. Bruce Vogelaar.

  12. Quantitative Comparison of Commercial and Non-Commercial Metal Artifact Reduction Techniques in Computed Tomography

    NARCIS (Netherlands)

    Wagenaar, Dirk; van der Graaf, Emiel R.; van der Schaaf, Arjen; Greuter, Marcel J. W.


    Objectives Typical streak artifacts known as metal artifacts occur in the presence of strongly attenuating materials in computed tomography (CT). Recently, vendors have started offering metal artifact reduction (MAR) techniques. In addition, a MAR technique called the metal deletion technique (MDT)

  13. TH-C-BRD-06: A Novel MRI Based CT Artifact Correction Method for Improving Proton Range Calculation in the Presence of Severe CT Artifacts

    International Nuclear Information System (INIS)

    Park, P; Schreibmann, E; Fox, T; Roper, J; Elder, E; Tejani, M; Crocker, I; Curran, W; Dhabaan, A


    Purpose: Severe CT artifacts can impair our ability to accurately calculate proton range thereby resulting in a clinically unacceptable treatment plan. In this work, we investigated a novel CT artifact correction method based on a coregistered MRI and investigated its ability to estimate CT HU and proton range in the presence of severe CT artifacts. Methods: The proposed method corrects corrupted CT data using a coregistered MRI to guide the mapping of CT values from a nearby artifact-free region. First patient MRI and CT images were registered using 3D deformable image registration software based on B-spline and mutual information. The CT slice with severe artifacts was selected as well as a nearby slice free of artifacts (e.g. 1cm away from the artifact). The two sets of paired MRI and CT images at different slice locations were further registered by applying 2D deformable image registration. Based on the artifact free paired MRI and CT images, a comprehensive geospatial analysis was performed to predict the correct CT HU of the CT image with severe artifact. For a proof of concept, a known artifact was introduced that changed the ground truth CT HU value up to 30% and up to 5cm error in proton range. The ability of the proposed method to recover the ground truth was quantified using a selected head and neck case. Results: A significant improvement in image quality was observed visually. Our proof of concept study showed that 90% of area that had 30% errors in CT HU was corrected to 3% of its ground truth value. Furthermore, the maximum proton range error up to 5cm was reduced to 4mm error. Conclusion: MRI based CT artifact correction method can improve CT image quality and proton range calculation for patients with severe CT artifacts

  14. Perspectives on digital computational systems as aesthetic artifacts

    Directory of Open Access Journals (Sweden)

    Luísa Ribas


    Full Text Available This paper addresses the study of digital computational systems as aesthetic artifacts seeking to provide instruments for their analysis and critical understanding. What this aim implies is the need to articulate complementary perspectives for considering not only their specificity as digital computational (software-driven systems, but also the different aesthetic intents that drive the creation of these artifacts, as well as the kinds of experience they propose. This approach entails articulating the viewpoint of their creation or poetics with the viewpoint of their experience or aesthetics, while tackling into their enacted processes. Accordingly, this paper discusses concepts, models and frameworks that not only argue on the distinctive processual nature of these systems, but also stress the interdependency of views on their principles, mechanics and experience.

  15. Interpolation strategies for reducing IFOV artifacts in microgrid polarimeter imagery. (United States)

    Ratliff, Bradley M; LaCasse, Charles F; Tyo, J Scott


    Microgrid polarimeters are composed of an array of micro-polarizing elements overlaid upon an FPA sensor. In the past decade systems have been designed and built in all regions of the optical spectrum. These systems have rugged, compact designs and the ability to obtain a complete set of polarimetric measurements during a single image capture. However, these systems acquire the polarization measurements through spatial modulation and each measurement has a varying instantaneous field-of-view (IFOV). When these measurements are combined to estimate the polarization images, strong edge artifacts are present that severely degrade the estimated polarization imagery. These artifacts can be reduced when interpolation strategies are first applied to the intensity data prior to Stokes vector estimation. Here we formally study IFOV error and the performance of several bilinear interpolation strategies used for reducing it.

  16. Woodworm Disinfestation of Wooden Artifacts by Vacuum Techniques

    Directory of Open Access Journals (Sweden)

    Giuseppe Chidichimo


    Full Text Available Wooden artifacts are subject to being heavily damaged by the attack of worms which develop in the wood through the eggs deposited by adult pests before their final transformation into flying insects. Among the most dangerous species are xylophagous (wood-boring insects, whose larvae are responsible for one of the most efficient wood-destroying mechanisms in wooden cultural heritage. Their elimination has always been a huge problem for the conservation of wood. In this work, we present the experimentation of a simple vacuum technique to disinfest wood from the larval Hylotrupes bajolus. We will also introduce the possibility of treating large-sized wooden artifacts by means of a special vacuum chamber.

  17. Inter-deriving Semantic Artifacts for Object-Oriented Programming

    DEFF Research Database (Denmark)

    Danvy, Olivier; Johannsen, Jacob


    .e., big-step operational semantics) specified in Abadi and Cardelli's monograph. This abstract machine therefore embodies the soundness of Abadi and Cardelli's reduction semantics and natural semantics relative to each other. To move closer to actual implementations, which use environments rather than......We present a new abstract machine for Abadi and Cardelli's untyped calculus of objects. What is special about this semantic artifact (i.e., man-made construct) is that is mechanically corresponds to both the reduction semantics (i.e., small-step operational semantics) and the natural semantics (i...... actual substitutions, we then represent object methods as closures and in the same inter-derivational spirit, we present three new semantic artifacts: a reduction semantics for a version of Abadi and Cardelli's untyped calculus of objects with explicit substitutions, an environment-based abstract machine...

  18. DBS artifact suppression using a time-frequency domain filter. (United States)

    Santillán-Guzmán, Alina; Heute, Ulrich; Muthuraman, Muthuraman; Stephani, Ulrich; Galka, Andreas


    Electroencephalogram (EEG) is a useful tool for brain research. However, during Deep-Brain Stimulation (DBS), there are large artifacts that obscure the physiological EEG signals. In this paper, we aim at suppressing the DBS artifacts by means of a time-frequency-domain filter. As a pre-processing step, Empirical-Mode Decomposition (EMD) is applied to detrend the raw data. The detrended signals are then filtered iteratively until, by visual inspection, the quality is good enough for interpretation. The proposed algorithm is demonstrated by an application to a clinical DBS-EEG data set in resting state and in finger-tapping condition. Moreover, a comparison with a Low-Pass filter (LPF) is provided, by visual inspection and by a quantitative measure.

  19. Two-dimensional analysis of motion artifacts, including flow effects

    International Nuclear Information System (INIS)

    Litt, A.M.; Brody, A.S.; Spangler, R.A.; Scott, P.D.


    The effects of motion on magnetic resonance images have been theoretically analyzed for the case of a point-like object in simple harmonic motion and for other one-dimensional trajectories. The authors of this paper extend this analysis to a generalized two-dimensional magnetization with an arbitrary motion trajectory. The authors provide specific solutions for the clinically relevant cases of the cross-sections of cylindrical objects in the body, such as the aorta, which has a roughly one-dimensional, simple harmonic motion during respiration. By extending the solution to include inhomogeneous magnetizations, the authors present a model which allows the effects of motion artifacts and flow artifacts to be analyzed simultaneously

  20. Humans perceive flicker artifacts at 500 Hz. (United States)

    Davis, James; Hsieh, Yi-Hsuan; Lee, Hung-Chi


    Humans perceive a stable average intensity image without flicker artifacts when a television or monitor updates at a sufficiently fast rate. This rate, known as the critical flicker fusion rate, has been studied for both spatially uniform lights, and spatio-temporal displays. These studies have included both stabilized and unstablized retinal images, and report the maximum observable rate as 50-90 Hz. A separate line of research has reported that fast eye movements known as saccades allow simple modulated LEDs to be observed at very high rates. Here we show that humans perceive visual flicker artifacts at rates over 500 Hz when a display includes high frequency spatial edges. This rate is many times higher than previously reported. As a result, modern display designs which use complex spatio-temporal coding need to update much faster than conventional TVs, which traditionally presented a simple sequence of natural images.

  1. Santeria and Palo Mayombe: skulls, mercury, and artifacts. (United States)

    Gill, James R; Rainwater, Christopher W; Adams, Bradley J


    Santeria and Palo Mayombe are syncretic religions created in the New World based upon African religious beliefs combined with Christianity. The main worship of Palo Mayombe involves religious receptacles that may contain earth, sticks, varied artifacts, and animal and human remains. Due to the use of human and nonhuman remains, discovery of these items often leads to involvement by the police due to a concern of homicide. We review in detail the medical examiner records of two of these ritualistic cases including the autopsy, anthropology, police, and investigators' reports. For the human remains, careful consideration of the context in which the remains were recovered, their state of preservation, and the associated artifacts (e.g., beads and mercury) are important in determining the appropriate level of forensic significance. Anthropological examination with particular attention to taphonomic characteristics also may help determine the origin and forensic significance.

  2. Sharing of secondary electrons by in-lens and out-lens detector in low-voltage scanning electron microscope equipped with immersion lens. (United States)

    Kumagai, Kazuhiro; Sekiguchi, Takashi


    To understand secondary electron (SE) image formation with in-lens and out-lens detector in low-voltage scanning electron microscopy (LV-SEM), we have evaluated SE signals of an in-lens and an out-lens detector in LV-SEM. From the energy distribution spectra of SEs with various boosting voltages of the immersion lens system, we revealed that the electrostatic field of the immersion lens mainly collects electrons with energy lower than 40eV, acting as a low-pass filter. This effect is also observed as a contrast change in LV-SEM images taken by in-lens and out-lens detectors.

  3. Classification of independent components of EEG into multiple artifact classes

    DEFF Research Database (Denmark)

    Frølich, Laura; Andersen, Tobias; Mørup, Morten


    In this study, we aim to automatically identify multiple artifact types in EEG. We used multinomial regression to classify independent components of EEG data, selecting from 65 spatial, spectral, and temporal features of independent components using forward selection. The classifier identified...... neural and five nonneural types of components. Between subjects within studies, high classification performances were obtained. Between studies, however, classification was more difficult. For neural versus nonneural classifications, performance was on par with previous results obtained by others. We...

  4. Why and How to Control Cloning in Software Artifacts


    Juergens, Elmar


    Software cloning is a well-known software quality defect. Nevertheless, it abounds in practice -- across artifacts, organizations and domains. This has two principal reasons: first, the significance of cloning is not well understood. Second, no comprehensive method exists that guides practitioners to establish successful clone control. This thesis contributes to both areas. First, we present empirical results on the significance of cloning. Our case studies on source code, requirements specif...

  5. Artifacts and pitfalls in shoulder magnetic resonance imaging


    Marcon, Gustavo Felix; Macedo, Tulio Augusto Alves


    AbstractMagnetic resonance imaging has revolutionized the diagnosis of shoulder lesions, in many cases becoming the method of choice. However, anatomical variations, artifacts and the particularity of the method may be a source of pitfalls, especially for less experienced radiologists. In order to avoid false-positive and false-negative results, the authors carried out a compilation of imaging findings that may simulate injury. It is the authors’ intention to provide a useful, consistent and ...

  6. Carbon fiber intramedullary nails reduce artifact in postoperative advanced imaging

    International Nuclear Information System (INIS)

    Zimel, Melissa N.; Hwang, Sinchun; Riedel, Elyn R.; Healey, John H.


    This study assessed whether radiolucent carbon fiber reinforced-polyetheretherketone (CFR-PEEK) intramedullary nails decreased hardware artifact on magnetic resonance imaging (MRI) and computed tomography (CT) in vitro and in an oncologic patient population. In vitro and clinical evaluations were done. A qualitative assessment of metal artifact was performed using CFR-PEEK and titanium nail MRI phantoms. Eight patients with a femoral or tibial prophylactic CFR-PEEK nail were retrospectively identified. All patients had postoperative surveillance imaging by MRI, CT, and were followed for a median 20 months (range, 12-28 months). CFR-PEEK images were compared to images from a comparative group of patients with titanium femoral intramedullary nails who had a postoperative MRI or CT. A musculoskeletal-trained radiologist graded visualization of the cortex, corticomedullary junction, and bone-muscle interface, on T1-weighted (T1W), STIR, and contrast-enhanced T1-weighted fat-saturated (T1W FS) sequences of both groups with a five-point scale, performing independent reviews 4 months apart. Statistical analysis used the Wilcoxon rank-sum test and a weighted kappa. Substantially less MRI signal loss occurred in the CFR-PEEK phantom than in the titanium phantom simulation, particularly as the angle increased with respect to direction of the static magnetic field. CFR-PEEK nails had less MRI artifact than titanium nails on scored T1W, STIR, and contrast-enhanced T1W FS MRI sequences (p ≤ 0.03). The mean weighted kappa was 0.64, showing excellent intraobserver reliability between readings. CFR-PEEK intramedullary nail fixation is a superior alternative to minimize implant artifact on MRI or CT imaging for patients requiring long bone fixation. (orig.)

  7. Essential Layers, Artifacts, and Dependencies of Enterprise Architecture


    Winter, Robert; Fischer, Ronny


    After a period where implementation speed was more important than integration, consistency and reduction of complexity, architectural considerations have become a key issue of information management in recent years again. Enterprise architecture is widely accepted as an essential mechanism for ensuring agility and consistency, compliance and efficiency. Although standards like TOGAF and FEAF have developed, however, there is no common agreement on which architecture layers, which artifact typ...

  8. Interslice leakage artifact reduction technique for simultaneous multislice acquisitions. (United States)

    Cauley, Stephen F; Polimeni, Jonathan R; Bhat, Himanshu; Wald, Lawrence L; Setsompop, Kawin


    Controlled aliasing techniques for simultaneously acquired echo-planar imaging slices have been shown to significantly increase the temporal efficiency for both diffusion-weighted imaging and functional magnetic resonance imaging studies. The "slice-GRAPPA" (SG) method has been widely used to reconstruct such data. We investigate robust optimization techniques for SG to ensure image reconstruction accuracy through a reduction of leakage artifacts. Split SG is proposed as an alternative kernel optimization method. The performance of Split SG is compared to standard SG using data collected on a spherical phantom and in vivo on two subjects at 3 T. Slice-accelerated and nonaccelerated data were collected for a spin-echo diffusion-weighted acquisition. Signal leakage metrics and time-series SNR were used to quantify the performance of the kernel fitting approaches. The Split SG optimization strategy significantly reduces leakage artifacts for both phantom and in vivo acquisitions. In addition, a significant boost in time-series SNR for in vivo diffusion-weighted acquisitions with in-plane 2× and slice 3× accelerations was observed with the Split SG approach. By minimizing the influence of leakage artifacts during the training of SG kernels, we have significantly improved reconstruction accuracy. Our robust kernel fitting strategy should enable better reconstruction accuracy and higher slice-acceleration across many applications. Copyright © 2013 Wiley Periodicals, Inc.

  9. Detection of movement artifact in recorded pulse oximeter saturation. (United States)

    Poets, C F; Stebbens, V A


    Movement artifact (MA) must be detected when analysing recordings of pulse oximeter saturation (SpO2). Visual analysis of individual pulse waveforms is the safest, but also the most tedious, method for this purpose. We wanted to test the reliability of a computer algorithm (Edentec Motion Annotation System), based on a comparison between pulse and heart rate, for MA detection. Ten 12-h recordings of SpO2, pulse waveforms and heart rate from ten preterm infants were analysed for the presence of MA on the pulse waveform signal. These data were used to determine the sensitivity and specificity of the computer algorithm, and of the oximeter itself, in detecting MA. Recordings were divided into segments of 2.5 s duration to compare the movement identification methods. Of the segments 31% +/- 6% (mean +/- SD) contained MA. The computer algorithm identified 95% +/- 3% of these segments, the pulse oximeter only 18% +/- 11%. Specificity was 85% +/- 4% and 99% +/- 0%, respectively. SpO2 was signal showed MA during this time, leaving a significant potential for erroneous identification of hypoxaemia. Recordings of SpO2 do not allow a reliable identification of MA. Without additional information about movement artifact, a significant proportion of recording time of pulse oximeter signal may be regarded as demonstrating hypoxaemia which, in fact, simply reflects poor measurement conditions. The computer algorithm used in this study identified periods of movement artifact reliably.

  10. Preventing Rape of the Observatory: Thoughts on the Urgency of Preserving Historic Astronomical Artifacts (United States)

    Bell, T. E.


    "What good is this century-old monster refractor? Sell it and use the money to buy a brand new go-to reflector useful for teaching students and advancing astronomy." So argues logic that is endangering an increasing number of university observatories around the U.S. (if not the rest of the world), even up to the Yerkes Observatory and its 40-inch Clark, world's largest refractor by the acknowledged world's best lens-makers. While most non-historians readily accept the value of preserving our cultural heritage in rare and precious documents (such as the Declaration of Independence), artifacts (such as Stradivarius violins), and institutions (such as the birthplaces of U.S. Presidents), they tend not to think of astronomical observatories as part of cultural heritage-with a result that history is crumbling apace to the wrecking ball. In early October, the Antique Telescope Society convened a special 60-minute session discussing philosophical why's and practical how's of preserving astronomical assets (including historically significant telescopes, observatory buildings, auxiliary equipment used to make observations or calculate results, and libraries of books and papers). This paper will summarize the discussion's key insights - including the assessing and assigning of value to old vs. new telescopes, and the roles of politics, funding and fund-raising, publicity (positive and negative), education, use as a form of preservation, innovative solutions by private collectors (including "half-way houses" for homeless instruments), restoration vs. renovation, special problems facing very large telescopes, and lessons learned from both failures and success.

  11. Acanthamoeba keratitis and contact lens wear. (United States)

    Lindsay, Richard G; Watters, Grant; Johnson, Richard; Ormonde, Susan E; Snibson, Grant R


    Acanthamoeba keratitis is a rare but serious complication of contact lens wear that may cause severe visual loss. The clinical picture is usually characterised by severe pain, sometimes disproportionate to the signs, with an early superficial keratitis that is often misdiagnosed as herpes simplex virus (HSV) keratitis. Advanced stages of the infection are usually characterised by central corneal epithelial loss and marked stromal opacification with subsequent loss of vision. In this paper, six cases of contact lens-related Acanthamoeba keratitis that occurred in Australia and New Zealand over a three-year period are described. Three of the patients were disposable soft lens wearers, two were hybrid lens wearers and one was a rigid gas permeable lens wearer. For all six cases, the risk factors for Acanthamoeba keratitis were contact lens wear with inappropriate or ineffective lens maintenance and exposure of the contact lenses to tap or other sources of water. All six patients responded well to medical therapy that involved topical use of appropriate therapeutic agents, most commonly polyhexamethylene biguanide and propamidine isethionate, although two of the patients also subsequently underwent deep lamellar keratoplasty due to residual corneal surface irregularity and stromal scarring. Despite the significant advances that have been made in the medical therapy of Acanthamoeba keratitis over the past 10 years, prevention remains the best treatment and patients who wear contact lenses must be thoroughly educated about the proper use and care of the lenses. In particular, exposure of the contact lenses to tap water or other sources of water should be avoided.

  12. Properties of the cathode lens combined with a focusing magnetic/immersion-magnetic lens

    International Nuclear Information System (INIS)

    Konvalina, I.; Muellerova, I.


    The cathode lens is an electron optical element in an emission electron microscope accelerating electrons from the sample, which serves as a source for a beam of electrons. Special application consists in using the cathode lens first for retardation of an illuminating electron beam and then for acceleration of reflected as well as secondary electrons, made in the directly imaging low energy electron microscope or in its scanning version discussed here. In order to form a real image, the cathode lens has to be combined with a focusing magnetic lens or a focusing immersion-magnetic lens, as used for objective lenses of some commercial scanning electron microscopes. These two alternatives are compared with regards to their optical properties, in particular with respect to predicted aberration coefficients and the spot size, as well as the optimum angular aperture of the primary beam. The important role of the final aperture size on the image resolution is also presented.

  13. Lens exposure during brain scans using multidetector row CT scanners: methods for estimation of lens dose. (United States)

    Suzuki, S; Furui, S; Ishitake, T; Abe, T; Machida, H; Takei, R; Ibukuro, K; Watanabe, A; Kidouchi, T; Nakano, Y


    Some recent studies on radiation lens injuries have indicated much lower dose thresholds than specified by the current radiation protection guidelines. The purpose of this research was to measure the lens dose during brain CT scans with multidetector row CT and to assess methods for estimating the lens dose. With 8 types of multidetector row CT scanners, both axial and helical scans were obtained for the head part of a human-shaped phantom by using normal clinical settings with the orbitomeatal line as the baseline. We measured the doses on both eyelids by using an RPLGD during whole-brain scans including the orbit with the starting point at the level of the inferior orbital rim. To assess the effect of the starting points on the lens doses, we measured the lens doses by using 2 other starting points for scanning (the orbitomeatal line and the superior orbital rim). The CTDIvols and the lens doses during whole-brain CT including the orbit were 50.9-113.3 mGy and 42.6-103.5 mGy, respectively. The ratios of lens dose to CTDIvol were 80.6%-103.4%. The lens doses decreased as the starting points were set more superiorly. The lens doses during scans from the superior orbital rim were 11.8%-20.9% of the doses during the scans from the inferior orbital rim. CTDIvol can be used to estimate the lens dose during whole-brain CT when the orbit is included in the scanning range.

  14. Removal of ring artifacts in microtomography by characterization of scintillator variations. (United States)

    Vågberg, William; Larsson, Jakob C; Hertz, Hans M


    Ring artifacts reduce image quality in tomography, and arise from faulty detector calibration. In microtomography, we have identified that ring artifacts can arise due to high-spatial frequency variations in the scintillator thickness. Such variations are normally removed by a flat-field correction. However, as the spectrum changes, e.g. due to beam hardening, the detector response varies non-uniformly introducing ring artifacts that persist after flat-field correction. In this paper, we present a method to correct for ring artifacts from variations in scintillator thickness by using a simple method to characterize the local scintillator response. The method addresses the actual physical cause of the ring artifacts, in contrary to many other ring artifact removal methods which rely only on image post-processing. By applying the technique to an experimental phantom tomography, we show that ring artifacts are strongly reduced compared to only making a flat-field correction.

  15. Metal Artifact Suppression in Dental Cone Beam Computed Tomography Images Using Image Processing Techniques. (United States)

    Johari, Masoumeh; Abdollahzadeh, Milad; Esmaeili, Farzad; Sakhamanesh, Vahideh


    Dental cone beam computed tomography (CBCT) images suffer from severe metal artifacts. These artifacts degrade the quality of acquired image and in some cases make it unsuitable to use. Streaking artifacts and cavities around teeth are the main reason of degradation. In this article, we have proposed a new artifact reduction algorithm which has three parallel components. The first component extracts teeth based on the modeling of image histogram with a Gaussian mixture model. Striking artifact reduction component reduces artifacts using converting image into the polar domain and applying morphological filtering. The third component fills cavities through a simple but effective morphological filtering operation. Finally, results of these three components are combined into a fusion step to create a visually good image which is more compatible to human visual system. Results show that the proposed algorithm reduces artifacts of dental CBCT images and produces clean images.

  16. Development of Powerhouse Using Fresnel lens

    Directory of Open Access Journals (Sweden)

    Al-Dohani Nawar Saif


    Full Text Available Solar energy is an alternative source of renewable energy. Sultanate of Oman government showed initiation on utilization of solar energy for domestic and industrial applications. Fresnel lens is one of the methods to collect maximum energy by gathering heat of the sun in the concentrated form (using solar collectors. Earlier research work discloses that Fresnel lens gave better result in terms of power output and produces lower heat loss as compared to linear –parabolic solar collectors. In this work, development of a proto Fresnel lens power house was made to generate electricity. The focused heat from Fresnel lens was used to heat the molten salt in a heat exchanger to produce the steam. The generated steam was used to rotate the steam engine coupled to a generator. In the current work, a maximum power of 30 W was produced. In addition, comparative study was carried out regarding solar salts and heat exchanger materials to understand the Fresnel powerhouse performance. Overall the present study gave valuable information regarding usage of Fresnel lens for electricity generation in Oman.

  17. Non-compliance in contact lens wear. (United States)

    Claydon, B E; Efron, N


    Non-compliance is emerging as a critical issue in the contact lens field. This problem has been studied at depth in general health care situations and is seen as the responsibility of both practitioner and patient (client) working in a health care partnership. The contact lens practitioner and patient present a specific case for the study of non-compliance in areas such as hygiene, solution use, appointment attendance and wearing times. From 40 to 91% of contact lens patients have been reported as non-complaint in the use of recommended care and maintenance regimens and many of these are confused or ignorant about their behaviour. In order to arrive at a general set of conclusions from the studies published to date, it is important to understand the methodology of each study, it purpose, the definition of non-compliance used and the way the results were analysed and described. This review summarizes the research into non-compliance in the contact lens field to data. A set of general conclusions is drawn and a model for compliance in the context of contact lens practice is proposed.

  18. Spherical aberration in contact lens wear. (United States)

    Lindskoog Pettersson, A; Jarkö, C; Alvin, A; Unsbo, P; Brautaset, R


    The aim of the present studies was to investigate the effect on spherical aberration of different non custom-made contact lenses, both with and without aberration control. A wavefront analyser (Zywave, Bausch & Lomb) was used to measure the aberrations in each subject's right eye uncorrected and with the different contact lenses. The first study evaluated residual spherical aberration with a standard lens (Focus Dailies Disposable, Ciba Vision) and with an aberration controlled contact lens (ACCL) (Definition AC, Optical Connection Inc.). The second study evaluated the residual spherical aberrations with a monthly disposable silicone hydrogel lens with aberration reduction (PureVision, Bausch & Lomb). Uncorrected spherical aberration was positive for all pupil sizes in both studies. In the first study, residual spherical aberration was close to zero with the standard lens for all pupil sizes whereas the ACCL over-corrected spherical aberration. The results of the second study showed that the monthly disposable lens also over-corrected the aberration making it negative. The changes in aberration were statistically significant (plenses. Since the amount of aberration varies individually we suggest that aberrations should be measured with lenses on the eye if the aim is to change spherical aberration in a certain direction.

  19. A lazy way to design infrared lens (United States)

    Qiu, RongSheng; Wu, JianDong; Chen, LongJiang; Yu, Kun; Pang, HaoJun; Hu, BaiZhen


    We designed a compact middle-wave infrared (MWIR) lens with a large focal length ratio (about 1.5:1), used in the 3.7 to 4.8 μm range. The lens is consisted of a compact front group and a re-imaging group. Thanks to the compact front group configuration, it is possible to install a filter wheel mechanism in such a tight space. The total track length of the lens is about 50mm, which includes a 2mm thick protective window and a cold shield of 12mm. The full field of view of the lens is about 3.6°, and F number is less than 1.6, the image circle is about 4.6mm in diameter. The design performance of the lens reaches diffraction limitation, and doesn't change a lot during a temperature range of -40°C +60°C. This essay proposed a stepwise design method of infrared optical system guided by the qualitative approach. The method fully utilize the powerful global optimization ability, with a little effort to write code snippet in optical design software, frees optical engineer from tedious calculation of the original structure.

  20. TESS Lens-Bezel Assembly Modal Testing (United States)

    Dilworth, Brandon J.; Karlicek, Alexandra


    The Transiting Exoplanet Survey Satellite (TESS) program, led by the Kavli Institute for Astrophysics and Space Research at the Massachusetts Institute of Technology (MIT) will be the first-ever spaceborne all-sky transit survey. MIT Lincoln Laboratory is responsible for the cameras, including the lens assemblies, detector assemblies, lens hoods, and camera mounts. TESS is scheduled to be launched in August of 2017 with the primary goal to detect small planets with bright host starts in the solar neighborhood, so that detailed characterizations of the planets and their atmospheres can be performed. The TESS payload consists of four identical cameras and a data handling unit. Each camera consists of a lens assembly with seven optical elements and a detector assembly with four charge-coupled devices (CCDs) including their associated electronics. The optical prescription requires that several of the lenses are in close proximity to a neighboring element. A finite element model (FEM) was developed to estimate the relative deflections between each lens-bezel assembly under launch loads to predict that there are adequate clearances preventing the lenses from making contact. Modal tests using non-contact response measurements were conducted to experimentally estimate the modal parameters of the lens-bezel assembly, and used to validate the initial FEM assumptions. Key Words Non-contact measurements, modal analysis, model validation

  1. Isolating gait-related movement artifacts in electroencephalography during human walking (United States)

    Kline, Julia E.; Huang, Helen J.; Snyder, Kristine L.; Ferris, Daniel P.


    Objective. High-density electroencephelography (EEG) can provide an insight into human brain function during real-world activities with walking. Some recent studies have used EEG to characterize brain activity during walking, but the relative contributions of movement artifact and electrocortical activity have been difficult to quantify. We aimed to characterize movement artifact recorded by EEG electrodes at a range of walking speeds and to test the efficacy of artifact removal methods. We also quantified the similarity between movement artifact recorded by EEG electrodes and a head-mounted accelerometer. Approach. We used a novel experimental method to isolate and record movement artifact with EEG electrodes during walking. We blocked electrophysiological signals using a nonconductive layer (silicone swim cap) and simulated an electrically conductive scalp on top of the swim cap using a wig coated with conductive gel. We recorded motion artifact EEG data from nine young human subjects walking on a treadmill at speeds from 0.4 to 1.6 m s-1. We then tested artifact removal methods including moving average and wavelet-based techniques. Main results. Movement artifact recorded with EEG electrodes varied considerably, across speed, subject, and electrode location. The movement artifact measured with EEG electrodes did not correlate well with head acceleration. All of the tested artifact removal methods attenuated low-frequency noise but did not completely remove movement artifact. The spectral power fluctuations in the movement artifact data resembled data from some previously published studies of EEG during walking. Significance. Our results suggest that EEG data recorded during walking likely contains substantial movement artifact that: cannot be explained by head accelerations; varies across speed, subject, and channel; and cannot be removed using traditional signal processing methods. Future studies should focus on more sophisticated methods for removal of EEG

  2. Idiosyncratic recognition of UUG/UUA codons by modified nucleoside 5-taurinomethyluridine, τm5U present at 'wobble' position in anticodon loop of tRNALeu: A molecular modeling approach.

    Directory of Open Access Journals (Sweden)

    Asmita S Kamble

    Full Text Available Lack of naturally occurring modified nucleoside 5-taurinomethyluridine (τm5U at the 'wobble' 34th position in tRNALeu causes mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS. The τm5U34 specifically recognizes UUG and UUA codons. Structural consequences of τm5U34 to read cognate codons have not been studied so far in detail at the atomic level. Hence, 50ns multiple molecular dynamics (MD simulations of various anticodon stem loop (ASL models of tRNALeu in presence and absence of τm5U34 along with UUG and UUA codons were performed to explore the dynamic behaviour of τm5U34 during codon recognition process. The MD simulation results revealed that τm5U34 recognizes G/A ending codons by 'wobble' as well as a novel 'single' hydrogen bonding interactions. RMSD and RMSF values indicate the comparative stability of the ASL models containing τm5U34 modification over the other models, lacking τm5U34. Another MD simulation study of 55S mammalian mitochondrial rRNA with tRNALeu showed crucial interactions between the A-site residues, A918, A919, G256 and codon-anticodon bases. Thus, these results could improve our understanding about the decoding efficiency of human mt tRNALeu with τm5U34 to recognize UUG and UUA codons.

  3. A mini-RNA containing the tetraloop, wobble-pair and loop E motifs of the central conserved region of potato spindle tuber viroid is processed into a minicircle. (United States)

    Schrader, O; Baumstark, T; Riesner, D


    A Mini-RNA from potato spindle tuber viroid (PSTVd) was constructed specifically for cleavage and ligation to circles in vitro. It contains the C-domain with the so-called central conserved region (CCR) of PSTVd with a 17 nt duplication in the upper strand and hairpin structures at the left and rights ends of the secondary structure. The CCR was previously shown to be essential for processing of in vitro transcripts. When folded under conditions which favor formation of a kinetically controlled conformation and incubated in a potato nuclear extract, the Mini-RNA is cleaved correctly at the 5'- and the 3'-end and ligated to a circle. Thus, the CCR obviously contains all structural and functional requirements for correct processing and therefore may be regarded as 'processing domain' of PSTVd. Using the Mini-RNA as a model substrate, the structural and functional relevance of its conserved non-canonical motifs GAAA tetraloop, loop E and G:U wobble base pair were studied by mutational analysis. It was found that (i) the conserved GAAA tetraloop is essential for processing by favoring the kinetically controlled conformation, (ii) a G:U wobble base pair at the 5'-cleavage site contributes to its correct recognition and (iii) an unpaired nucleotide in loop E, which is different from the corresponding nucleotide in the conserved loop E motif, is essential for ligation of the 5'- with the 3'-end. Hence all three structural motifs are functional elements for processing in a potato nuclear extract.

  4. Acanthamoeba, bacterial, and fungal contamination of contact lens storage cases. (United States)

    Gray, T B; Cursons, R T; Sherwan, J F; Rose, P R


    BACKGROUND--Microbial corneal infection is the most serious complication of contact lens wear. Contact lens cases are a recognised potential source of pathogens associated with corneal ulcers. METHODS--This survey established the incidence of protozoal, bacterial, and fungal contact lens case contamination in 101 asymptomatic daily wear cosmetic contact lens wearers from a domiciliary contact lens practice. RESULTS--Eighty two (81%) contact lens cases were found to be contaminated, with 19 (19%) sterile. Of all contact lens cases, 78 (77%) grew bacteria, 24 (24%) fungi, and 20 (20%) protozoa. Acanthamoeba spp were isolated from eight (8%) contact lens cases. Fifty six (55%) contact lens cases yielded mixed bacterial contamination. This is the first contact lens case survey in which hydrogen peroxide disinfection was the major method of contact lens disinfection (75% of subjects) and no home made saline was used. All the contaminating organisms were shown to possess the enzyme catalase that breaks down hydrogen peroxide to oxygen and water. The polymicrobial nature of the biofilms found in many contact lens cases is illustrated electron micrographically. CONCLUSION--Based on data from this and previous studies, the authors conclude with recommendations for contact lens wearers: (1) regular scrubbing of contact lens case interior to disrupt biofilms; (2) exposure of contact lens case to very hot water (> or = 70 degrees C) will kill Acanthamoeba contaminants; (3) allow contact lens case to air dry between uses; (4) if hydrogen peroxide disinfection is preferred, use a two step system; (5) replace contact lens case regularly. Images PMID:7626578

  5. Characterization of lens based photoacoustic imaging system

    Directory of Open Access Journals (Sweden)

    Kalloor Joseph Francis


    Full Text Available Some of the challenges in translating photoacoustic (PA imaging to clinical applications includes limited view of the target tissue, low signal to noise ratio and the high cost of developing real-time systems. Acoustic lens based PA imaging systems, also known as PA cameras are a potential alternative to conventional imaging systems in these scenarios. The 3D focusing action of lens enables real-time C-scan imaging with a 2D transducer array. In this paper, we model the underlying physics in a PA camera in the mathematical framework of an imaging system and derive a closed form expression for the point spread function (PSF. Experimental verification follows including the details on how to design and fabricate the lens inexpensively. The system PSF is evaluated over a 3D volume that can be imaged by this PA camera. Its utility is demonstrated by imaging phantom and an ex vivo human prostate tissue sample.

  6. Freeform micromachining of an infrared Alvarez lens (United States)

    Smilie, Paul J.; Dutterer, Brian S.; Lineberger, Jennifer L.; Davies, Matthew A.; Suleski, Thomas J.


    In 1967, Luis Alvarez introduced a novel concept for a focusing lens whereby two transmitting elements with cubic polynomial surfaces yield a composite lens of variable focal length with small lateral shifts. Computer simulations have demonstrated the behavior of these devices, but fabricating the refractive cubic surfaces of the types needed with adequate precision and depth modulation has proven to be challenging using standard methods, and, to the authors' knowledge, Alvarez lens elements have not been previously machined in infrared materials. Recent developments in freeform diamond machining capability have enabled the fabrication of such devices. In this paper, we discuss the fabrication of freeform refractive Alvarez elements in germanium using diamond micro-milling on a five-axis Moore Nanotech® 350FG Freeform Generator. Machining approaches are discussed, and measurements of surface figure and finish are presented. Initial experimental tests of optical performance are also discussed.

  7. Invited review article: the electrostatic plasma lens. (United States)

    Goncharov, Alexey


    The fundamental principles, experimental results, and potential applications of the electrostatic plasma lens for focusing and manipulating high-current, energetic, heavy ion beams are reviewed. First described almost 50 years ago, this optical beam device provides space charge neutralization of the ion beam within the lens volume, and thus provides an effective and unique tool for focusing high current beams where a high degree of neutralization is essential to prevent beam blow-up. Short and long lenses have been explored, and a lens in which the magnetic field is provided by rare-earth permanent magnets has been demonstrated. Applications include the use of this kind of optical tool for laboratory ion beam manipulation, high dose ion implantation, heavy ion accelerator injection, in heavy ion fusion, and other high technology.

  8. 3D printed helical antenna with lens

    KAUST Repository

    Farooqui, Muhammad Fahad


    The gain of an antenna can be enhanced through the integration of a lens, however this technique has traditionally been restricted to planar antennas due to fabrication limitations of standard manufacturing processes. Here, with a unique combination of 3D and 2D inkjet printing of dielectric and metallic inks respectively, we demonstrate a Fresnel lens that has been monolithically integrated to a non-planar antenna (helix) for the first time. Antenna measurements show that the integration of a Fresnel lens enhances the gain of a 2-turn helix by around 4.6 dB giving a peak gain of about 12.9 dBi at 8.8 GHz.

  9. An "ESA-affordable" Laue-lens

    DEFF Research Database (Denmark)

    Lund, Niels


    With ESA's INTEGRAL mission gamma-ray astronomy has advanced to the point where major scientific advances must be expected from detailed studies of the many new point sources. The interest in developing focusing telescopes operating in the soft gamma-ray regime up to 1 MeV is therefore mounting r...... constraints of a specific medium size launch vehicle. The introduction of the lens mass as a primary design driver has some surprising effects for the choice of material for the crystals and new tradeoff considerations are introduced....... rapidly. Telescopes based on Laue diffraction of gamma-rays from crystals appear as one promising route, although the practical difficulties of realizing a large scale Laue lens are certainly not small. In this paper I have attempted to develop an optimized lens design considering the size and mass...

  10. The effectiveness of soft contact lens disinfection systems against Acanthamoeba on the lens surface. (United States)

    Liedel, K K; Begley, C G


    This investigation compared the efficacy of three widely used contact lens disinfection systems against an ocular isolate of Acanthamoeba polyphaga. Twenty-seven worn Ciba NewVues lenses were quartered, heat sterilized and inoculated with Acanthamoeba. Lens quarters were then randomly assigned to three experimental groups, with Group A lenses exposed to cleaner and saline rinse only, Group B to disinfection only, and Group C to both cleaner and disinfection. One quarter of each lens served as a control and the other three quarters were experimental. Quantification of viable Acanthamoeba remaining on the lens was performed after each step of the disinfection process. Group A lenses showed no significant difference between the treatments, or the treatments and the control. Group B lenses demonstrated a significant difference (p = 0.0001) between the treatments and the control. In Group C (cleaning and disinfection), the control lens quarters were significantly different (p = 0.037) from the experimental group, but there was no significant difference between the treatments. All three disinfection regimens were very effective in reducing the number of viable Acanthamoeba on the contact lens surface. In the absence of proper cleaning (Group B), AOSept was the most effective of the three. These results also show the importance of thoroughly rubbing the contact lens surface to decrease the number of Acanthamoeba.

  11. Non-compliance with lens care and maintenance in diabetic contact lens wearers. (United States)

    O'Donnell, Clare; Efron, Nathan


    We hypothesize that diabetic contact lens wearers may represent a special group displaying higher levels of compliance with their lens care regimens as a result of learned behaviour relating to maintenance of their diabetic condition. To test this hypothesis, a prospective, single centre, controlled, masked study was performed whereby 29 diabetic contact lens patients and 29 non-diabetic control subjects were issued with disposable hydrogel contact lenses and a multipurpose lens care regimen. All participants were given identical instruction on lens care and maintenance. Compliance levels were assessed at a 12-month aftercare appointment by demonstration and questionnaire. Twenty-four different aspects of compliance were scored, 12 by observation and 12 by questionnaire report, of which only two showed a significant difference between the diabetic and control groups. Although the combined population of contact lens wearers was generally compliant, there were examples of non-compliance in both groups. Neither the duration of diabetes nor the degree of metabolic control appeared to have a significant effect on compliance. The results suggest that eye care practitioners cannot assume that diabetic patients will be more compliant with contact lens care and maintenance than non-diabetic patients.

  12. Analytic models of plausible gravitational lens potentials

    International Nuclear Information System (INIS)

    Baltz, Edward A.; Marshall, Phil; Oguri, Masamune


    Gravitational lenses on galaxy scales are plausibly modelled as having ellipsoidal symmetry and a universal dark matter density profile, with a Sérsic profile to describe the distribution of baryonic matter. Predicting all lensing effects requires knowledge of the total lens potential: in this work we give analytic forms for that of the above hybrid model. Emphasising that complex lens potentials can be constructed from simpler components in linear combination, we provide a recipe for attaining elliptical symmetry in either projected mass or lens potential. We also provide analytic formulae for the lens potentials of Sérsic profiles for integer and half-integer index. We then present formulae describing the gravitational lensing effects due to smoothly-truncated universal density profiles in cold dark matter model. For our isolated haloes the density profile falls off as radius to the minus fifth or seventh power beyond the tidal radius, functional forms that allow all orders of lens potential derivatives to be calculated analytically, while ensuring a non-divergent total mass. We show how the observables predicted by this profile differ from that of the original infinite-mass NFW profile. Expressions for the gravitational flexion are highlighted. We show how decreasing the tidal radius allows stripped haloes to be modelled, providing a framework for a fuller investigation of dark matter substructure in galaxies and clusters. Finally we remark on the need for finite mass halo profiles when doing cosmological ray-tracing simulations, and the need for readily-calculable higher order derivatives of the lens potential when studying catastrophes in strong lenses

  13. Photonic crystal based polarization insensitive flat lens (United States)

    Turduev, M.; Bor, E.; Kurt, H.


    The paper proposes a new design of an inhomogeneous artificially created photonic crystal lens structure consisting of annular dielectric rods to efficiently focus both transverse electric and transverse magnetic polarizations of light into the same focal point. The locations of each individual cell that contains the annular dielectric rods are determined according to a nonlinear distribution function. The inner and outer radii of the annular photonic dielectric rods are optimized with respect to the polarization insensitive frequency response of the transmission spectrum of the lens structure. The physical background of the polarization insensitive focusing mechanism is investigated in both spatial and frequency domains. Moreover, polarization independent wavefront transformation/focusing has been explored in detail by investigating the dispersion relation of the structure. Corresponding phase index distribution of the lens is attained for polarization insensitive normalized frequency range of a/λ  =  0.280 and a/λ  =  0.300, where a denotes the lattice constant of the designed structure and λ denotes the wavelength of the incident light. We show the wave transformation performance and focal point movement dynamics for both polarizations of the lens structure by specially adjusting the length of the structure. The 3D finite-difference time domain numerical analysis is also performed to verifiy that the proposed design is able to focus the wave regardless of polarization into approximately the same focal point (difference between focal distances of both polarizations stays below 0.25λ) with an operating bandwidth of 4.30% between 1476 nm and 1541 nm at telecom wavelengths. The main superiorities of the proposed lens structure are being all dielectric and compact, and having flat front and back surfaces, rendering the proposed lens design more practical in the photonic integration process in various applications such as optical switch

  14. Effect of infrared radiation on the lens

    Directory of Open Access Journals (Sweden)

    Aly Eman


    Full Text Available Background: Infrared (IR radiation is becoming more popular in industrial manufacturing processes and in many instruments used for diagnostic and therapeutic application to the human eye. Aim : The present study was designed to investigate the effect of IR radiation on rabbit′s crystalline lens and lens membrane. Materials and Methods: Fifteen New Zealand rabbits were used in the present work. The rabbits were classified into three groups; one of them served as control. The other two groups were exposed to IR radiation for 5 or 10 minutes. Animals from these two irradiated groups were subdivided into two subgroups; one of them was decapitated directly after IR exposure, while the other subgroup was decapitated 1 hour post exposure. IR was delivered from a General Electric Lamp model 250R 50/10, placed 20 cm from the rabbit and aimed at each eye. The activity of Na + -K + ATPase was measured in the lens membrane. Soluble lens proteins were extracted and the following measurements were carried out: estimation of total soluble protein, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE and Fourier transform infrared (FTIR spectroscopy. For comparison between multiple groups, analysis of variance was used with significance level set at P < 0.001. Results: The results indicated a change in the molecular weight of different lens crystalline accompanied with changes in protein backbone structure. These changes increased for the groups exposed to IR for 10 minutes. Moreover, the activity of Na + -K + ATPase significantly decreased for all groups. Conclusions: The protein of eye lens is very sensitive to IR radiation which is hazardous and may lead to cataract.

  15. The corneal stroma during contact lens wear. (United States)

    Jalbert, Isabelle; Stapleton, Fiona


    Recent technological advances have lead to novel descriptions of the microanatomy of the corneal stroma. In the first section of this review, these findings and the role they play in the maintenance of vital properties such as corneal transparency, mechanical strength, homeostasis, wound-healing response and metabolism are described. In the second part, contact lens induced stromal alterations such as acidosis, oedema, striae, thinning and opacities are reviewed as well as the more recently described phenomenon of microdot deposits and keratocyte loss with an emphasis on how lens wearing stromal effects can be minimised.

  16. Sterilization potential of contact lens solutions

    Directory of Open Access Journals (Sweden)

    Dada Vijay


    Full Text Available In a dynamic field of Contact Lens Solutions maintenance of high standards of anti-microbial activity is a must Resterilization Activity Time′ is a universally accepted yardstick for such an evaluation. In this study eight brands of indigenous popular solutions alongwith two FDA approved solutions were tested for their sterilization efficacy: Standardized suspensions of Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Aspergillus fumigatus were used for the purpose. It was observed that the contact lens solutions available ir, the domestic market were not upto the mark Suggestions for improvement have also been made.

  17. Rotman lens for mm-wavelengths (United States)

    Hall, Leonard T.; Hansen, Hedley J.; Abbott, Derek


    The 77 GHz band has been reserved for intelligent cruise control in luxury cars and some public transport services in America and the United Kingdom. The Rotman lens offers a cheap and compact means to extend the single beam systems generally used, to fully functional beam staring arrangements. Rotman lenses have been built for microwave frequencies with limited success. The flexibility of microstrip transmission lines and the advent of fast accurate simulation packages allow practical Rotman lenses to be designed at mm-wavelengths. This paper discusses the limitations of the conventional design approach and predicts the performance of a new Rotman lens designed at 77 GHz.

  18. Pulse transformer for the AA lithium lens

    CERN Document Server

    CERN PhotoLab


    The antiprotons emanating from the target were initially focused by a magnetic horn. Later on, a Li-lens was used during operation for the SPS collider, until 1992. A Li-rod (130 mm long, 34 mm in diameter) constituted the secondary of a 1:23 pulse-transformer. The half-sine pulse rose to 1000 kA in 900 microsec. The angular acceptance was 95 mrad. In operation after 1992, for LEAR only, a more modest Li-lens was used (155 mm long, diameter 20 mm, 480 kA, risetime 240 microsec, angular acceptance 75 mrad).

  19. Flexible Capacitive Electrodes for Minimizing Motion Artifacts in Ambulatory Electrocardiograms

    Directory of Open Access Journals (Sweden)

    Jeong Su Lee


    Full Text Available This study proposes the use of flexible capacitive electrodes for reducing motion artifacts in a wearable electrocardiogram (ECG device. The capacitive electrodes have conductive foam on their surface, a shield, an optimal input bias resistor, and guarding feedback. The electrodes are integrated in a chest belt, and the acquired signals are transmitted wirelessly for ambulatory heart rate monitoring. We experimentally validated the electrode performance with subjects standing and walking on a treadmill at speeds of up to 7 km/h. The results confirmed the highly accurate heart rate detection capacity of the developed system and its feasibility for daily-life ECG monitoring.

  20. Probabilistic expert systems for handling artifacts in complex DNA mixtures. (United States)

    Cowell, R G; Lauritzen, S L; Mortera, J


    This paper presents a coherent probabilistic framework for taking account of allelic dropout, stutter bands and silent alleles when interpreting STR DNA profiles from a mixture sample using peak size information arising from a PCR analysis. This information can be exploited for evaluating the evidential strength for a hypothesis that DNA from a particular person is present in the mixture. It extends an earlier Bayesian network approach that ignored such artifacts. We illustrate the use of the extended network on a published casework example. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  1. Development of an artifact-free aneurysm clip

    Directory of Open Access Journals (Sweden)

    Brack Alexander


    Full Text Available For the treatment of intracranial aneurysms with aneurysm clips, usually a follow-up inspection in MRI is required. To avoid any artifacts, which can make a proper diagnosis difficult, a new approach for the manufacturing of an aneurysm clip entirely made from fiber-reinforced plastics has been developed. In this paper the concept for the design of the clip, the development of a new manufacturing technology for the fiber-reinforced components as well as first results from the examination of the components in phantom MRI testing is shown.

  2. Gold-wire artifacts on diagnostic radiographs: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Keestra, Johan Anton Jochum; Jacobs, Reinhilde; Quirynen, Marc [Dept. of Oral Health Sciences, KU Leuven and Dentistry, University Hospitals, KU Leuven, Leuven (Belgium)


    This report described a case in which diagnostic radiographs showed irregular dense radiopaque strings and curved lines in the head and neck area. These artifacts could lead to misinterpretation since they may obscure anatomical structures and/or mask critical structures/pathologies. A more detailed history of the patient indicated that these strings originated from a facelift procedure in which a gold-wire technique was used. Considering that such intervention may cause a radiodiagnostic burden, it should be included in the anamnesis prior to radiography.

  3. Gold-wire artifacts on diagnostic radiographs: A case report

    International Nuclear Information System (INIS)

    Keestra, Johan Anton Jochum; Jacobs, Reinhilde; Quirynen, Marc


    This report described a case in which diagnostic radiographs showed irregular dense radiopaque strings and curved lines in the head and neck area. These artifacts could lead to misinterpretation since they may obscure anatomical structures and/or mask critical structures/pathologies. A more detailed history of the patient indicated that these strings originated from a facelift procedure in which a gold-wire technique was used. Considering that such intervention may cause a radiodiagnostic burden, it should be included in the anamnesis prior to radiography.

  4. The real deal: what judgments of really reveal about how people think about artifacts. (United States)

    Malt, Barbara C; Paquet, Michael R


    It is widely assumed that artifacts fall into distinct kinds. These kinds are generally identified by appeal to words-chair versus stool versus bowl versus vase, and so on. But contextual and cross-linguistic variation in what artifacts are grouped together by name raise questions about whether artifacts indeed do fall into fixed kinds. Can judgments of what artifacts really are reveal a true kind membership, distinct from what the objects are called in communicative contexts? In two experiments, we examined what drives judgments of what an artifact really is and what these judgments can tell us about how people think about artifacts. In both experiments, we found that people failed to treat artifacts as having a definitive kind membership in their judgments of what the artifacts really were. Instead, really judgments reflected the typicality of objects with respect to the things normally called by the queried name. If these judgments are taken as direct evidence about the existence of artifact kinds, the outcome argues against such kinds. Alternatively, really judgments themselves may be fundamentally linguistic in nature, and so unable to tap into underlying kind memberships. In either case, if such kinds exist, they remain to be found. A more likely reality may be that intuitions about the existence of artifact kinds reflect the partial clustering of objects in similarity space, plus the fact that each language provides names for some constellations of objects in that space.

  5. Artifacts in magnetic resonance imaging and computed tomography caused by dental materials.

    Directory of Open Access Journals (Sweden)

    Thomas Klinke

    Full Text Available BACKGROUND: Artifacts caused by dental restorations, such as dental crowns, dental fillings and orthodontic appliances, are a common problem in MRI and CT scans of the head and neck. The aim of this in-vitro study was to identify and evaluate the artifacts produced by different dental restoration materials in CT and MRI images. METHODS: Test samples of 44 materials (Metal and Non-Metal commonly used in dental restorations were fabricated and embedded with reference specimens in gelatin moulds. MRI imaging of 1.5T and CT scan were performed on the samples and evaluated in two dimensions. Artifact size and distortions were measured using a digital image analysis software. RESULTS: In MRI, 13 out of 44 materials produced artifacts, while in CT 41 out of 44 materials showed artifacts. Artifacts produced in both MRI and CT images were categorized according to the size of the artifact. SIGNIFICANCE: Metal based restoration materials had strong influence on CT and less artifacts in MRI images. Rare earth elements such as Ytterbium trifluoride found in composites caused artifacts in both MRI and CT. Recognizing these findings would help dental materials manufacturers and developers to produce materials which can cause less artifacts in MRI and CT images.

  6. Improved artifact rejection and isolation of compound action potentials by means of digital subtraction. (United States)

    Kiss, I; Shizgal, P


    When recording compound action potentials (CAPs) elicited by stimulating near the recording site, it may prove difficult to distinguish the CAP from the shock artifact because of their overlap in time. This problem is compounded when a pair of stimulation pulses is delivered because the CAP elicited by the test pulse (T pulse) may be partially superimposed on the artifact and response elicited by the conditioning pulse (C pulse) as well as on the T pulse artifact. Methods based on digital subtraction were used to address these problems. A record was obtained with the C-T interval adjusted to be slightly less than the absolute refractory period so that the T pulse would fail to elicit a CAP. A record consisting of a C pulse artifact and response was subtracted from this record to yield a 'pure' shock artifact. In principle, subtracting this 'artifact-only' record from records obtained with single pulses removes the shock artifact and yields a 'pure' response. An extension of this method was used to isolate T pulse responses from the C pulse artifact, C pulse response, and T pulse artifact. These methods proved effective in improving the isolation of the CAPs of interest from other features of the raw records. Limitations of the techniques and their complementarity with other methods of artifact reduction are discussed.

  7. Metal Artifact Reduction in Cone-Beam Computed Tomography for Head and Neck Radiotherapy. (United States)

    Korpics, Mark; Johnson, Paul; Patel, Rakesh; Surucu, Murat; Choi, Mehee; Emami, Bahman; Roeske, John C


    To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identifying metal regions in individual cone-beam computed tomography projections and interpolating the surrounding values to remove the metal from the projection data. Axial cone-beam computed tomography images are then reconstructed, resulting in a reduction in the streak artifacts produced by the metal. Both phantom and patient imaging data are used to evaluate this technique. The interpolation substitution technique successfully reduced metal artifacts in all cases. Corrected images had fewer or no streak artifacts compared to their noncorrected counterparts. Quantitatively, regions of interest containing the artifacts showed reduced variance in the corrected images versus the uncorrected images. Average pixel values in regions of interest around the metal object were also closer in value to nonmetal regions after artifact reduction. Artifact correction tended to perform better on patient images with less complex metal objects versus those with multiple large dental fillings. The interpolation substitution is potentially an efficient and effective technique for reducing metal artifacts caused by dental fillings on cone-beam computed tomography image. This technique may be effective in reducing such artifacts in patients with head and neck cancer receiving daily image-guided radiotherapy. © The Author(s) 2015.

  8. Immunochemical analyses of soluble lens proteins in some marine fishes

    Digital Repository Service at National Institute of Oceanography (India)

    Menezes, M.R.

    Soluble eye lens proteins of 10 fishes, belonging to the families Clupeidae, Hemirhamphidae, Lactaridae, Scombridae, Stromatidae, Psettodidae, Bothidae and Soleidae were studied by immunoelectrophoresis using the lens antiserum of Sardinella...

  9. IOL Implants: Lens Replacement and Cataract Surgery (Intraocular Lenses) (United States)

    ... Cataract Surgery vs. Laser-Assisted Cataract Surgery Cataract Vision Simulator Cataract Pictures and Videos: What Do ... Mar. 27, 2018 An intraocular lens (or IOL) is a tiny, artificial lens for the eye. It replaces the eye's ...

  10. Iterative image-domain ring artifact removal in cone-beam CT (United States)

    Liang, Xiaokun; Zhang, Zhicheng; Niu, Tianye; Yu, Shaode; Wu, Shibin; Li, Zhicheng; Zhang, Huailing; Xie, Yaoqin


    Ring artifacts in cone beam computed tomography (CBCT) images are caused by pixel gain variations using flat-panel detectors, and may lead to structured non-uniformities and deterioration of image quality. The purpose of this study is to propose a method of general ring artifact removal in CBCT images. This method is based on the polar coordinate system, where the ring artifacts manifest as stripe artifacts. Using relative total variation, the CBCT images are first smoothed to generate template images with fewer image details and ring artifacts. By subtracting the template images from the CBCT images, residual images with image details and ring artifacts are generated. As the ring artifact manifests as a stripe artifact in a polar coordinate system, the artifact image can be extracted by mean value from the residual image; the image details are generated by subtracting the artifact image from the residual image. Finally, the image details are compensated to the template image to generate the corrected images. The proposed framework is iterated until the differences in the extracted ring artifacts are minimized. We use a 3D Shepp-Logan phantom, Catphan©504 phantom, uniform acrylic cylinder, and images from a head patient to evaluate the proposed method. In the experiments using simulated data, the spatial uniformity is increased by 1.68 times and the structural similarity index is increased from 87.12% to 95.50% using the proposed method. In the experiment using clinical data, our method shows high efficiency in ring artifact removal while preserving the image structure and detail. The iterative approach we propose for ring artifact removal in cone-beam CT is practical and attractive for CBCT guided radiation therapy.

  11. Lens autofluorescence is not increased at high altitude

    DEFF Research Database (Denmark)

    Kessel, Line; Kofoed, Peter Kristian; Zubieta-Calleja, Gustavo


    PURPOSE: To study the relation between ambient environmental ultraviolet radiation exposure and lens fluorescence. METHODS: Non-invasive lens fluorometry measurements were compared in healthy Bolivian and Danish subjects. Background ultraviolet radiation was 4.5 times higher in Bolivia than in De...... living at sea level at 55 degrees northern latitude. These results suggest that lens ageing, as assessed by lens autofluorometry, is independent of exposure to ultraviolet radiation....

  12. 21 CFR 886.1420 - Ophthalmic lens gauge. (United States)


    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ophthalmic lens gauge. 886.1420 Section 886.1420...) MEDICAL DEVICES OPHTHALMIC DEVICES Diagnostic Devices § 886.1420 Ophthalmic lens gauge. (a) Identification. An ophthalmic lens gauge is a calibrated device intended to manually measure the curvature of a...

  13. In vivo study of lens regeneration in Rana cyanophlyctis under ...

    African Journals Online (AJOL)



    Mar 12, 2014 ... enhanced the percentage lens regeneration not only in young tadpoles but also in froglets. Lens regeneration ability ... Influence of vitamin A and ascorbic acid on lens regeneration in young, mature tadpoles and froglets of the frog Rana cyanophlyctis. Group .... ingested by macrophages. Dorsal iris cells ...

  14. 21 CFR 800.10 - Contact lens solutions; sterility. (United States)


    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Contact lens solutions; sterility. 800.10 Section...) MEDICAL DEVICES GENERAL Requirements for Specific Medical Devices § 800.10 Contact lens solutions... ophthalmic use, including contact lens solutions, should be sterile. It is further evident that such...

  15. Initial Experience With Posterior Chamber Intraocular Lens Implant ...

    African Journals Online (AJOL)

    The results of extracapsular cataract extraction with posterior chamber intraocular lens implant at the Jos University Teaching Hospital are reviewed. The results suggest that despite lack of facilities to calculate the lens power for emmetropia, the use of a standard lens of about 19.0D will provide a good number of our ...

  16. Mascara--an unsuspected cause of magnetic resonance imaging artifact. (United States)

    Smith, F W; Crosher, G A


    It is well recognised that metals, especially iron, will cause artifacts in magnetic resonance (MR) images. Hitherto it has not been recognised that some facial cosmetics contain magnetic materials, in sufficient quantities to cause artifacts. We report a case of a 25-year-old female who had MR images of her orbits made while wearing mascara eye makeup. The resultant images showed distortion of the signal over the anterior aspect of both eyes. Examination following the removal of the eye makeup resulted in the acquisition of normal images. The typical ingredients of mascara are natural and synthetic waxes, glycerine, water, kaolin, preservatives, polymer film formers and pigments. A wide range of pigments may be used, especially iron oxide, which is a constituent of both brown and blue mascara. In addition it is likely that a number of mascaras will be contaminated with heavy metals. As a result of this observation we now ensure that all patients who are undergoing MR imaging of the head, remove all facial cosmetics as well as any jewelry prior to imaging.

  17. Racial IQ Differences among Transracial Adoptees: Fact or Artifact?

    Directory of Open Access Journals (Sweden)

    Drew Thomas


    Full Text Available Some academic publications infer from studies of transracial adoptees’ IQs that East Asian adoptees raised in the West by Whites have higher IQs than Western Whites, and that White adoptees raised by Whites have higher IQs than Black adoptees raised by Whites. Those publications suggest that this is because genetic differences give East Asians a higher mean IQ than Whites, and Whites a higher mean IQ than Blacks. This paper proposes a parsimonious alternative explanation: the apparent IQ advantage of East Asian adoptees is an artifact caused by ignoring the Flynn effect and adoption’s beneficial effect on IQ, and most of the IQ disadvantage of Black adoptees disappears when one allows for attrition in the Minnesota Transracial Adoption Study, and acknowledges the results of other studies. Diagnosing these artifacts suggests a nil hypothesis: East Asian, White, and Black adoptees raised in the same environment would have similar IQs, hinting at a minimal role for genes in racial IQ differences.

  18. A generic approach to haptic modeling of textile artifacts (United States)

    Shidanshidi, H.; Naghdy, F.; Naghdy, G.; Wood Conroy, D.


    Haptic Modeling of textile has attracted significant interest over the last decade. In spite of extensive research, no generic system has been proposed. The previous work mainly assumes that textile has a 2D planar structure. They also require time-consuming measurement of textile properties in construction of the mechanical model. A novel approach for haptic modeling of textile is proposed to overcome the existing shortcomings. The method is generic, assumes a 3D structure for the textile, and deploys computational intelligence to estimate the mechanical properties of textile. The approach is designed primarily for display of textile artifacts in museums. The haptic model is constructed by superimposing the mechanical model of textile over its geometrical model. Digital image processing is applied to the still image of textile to identify its pattern and structure through a fuzzy rule-base algorithm. The 3D geometric model of the artifact is automatically generated in VRML based on the identified pattern and structure obtained from the textile image. Selected mechanical properties of the textile are estimated by an artificial neural network; deploying the textile geometric characteristics and yarn properties as inputs. The estimated mechanical properties are then deployed in the construction of the textile mechanical model. The proposed system is introduced and the developed algorithms are described. The validation of method indicates the feasibility of the approach and its superiority to other haptic modeling algorithms.

  19. Avoiding electromagnetic artifacts when recording auditory steady-state responses. (United States)

    Picton, Terence W; John, M Sasha


    Electromagnetic artifacts can occur when recording multiple auditory steady-state responses evoked by sinusoidally amplitude modulated (SAM) stimuli. High-intensity air-conducted stimuli evoked responses even when hearing was prevented by masking. Additionally, high-intensity bone-conducted stimuli evoked responses that were completely different from those evoked by air-conducted stimuli of similar sensory level. These artifacts were caused by aliasing since they did not occur when recordings used high analog-digital (AD) conversion rates or when high frequencies in the electroencephalographic (EEG) signal were attenuated by steep-slope low-pass filtering. Two possible techniques can displace aliased energy away from the response frequencies: (1) using an AD rate that is not an integer submultiple of the carrier frequencies and (2) using stimuli with frequency spectra that do not alias back to the response frequencies, such as beats or "alternating SAM" tones. Alternating SAM tones evoke responses similar to conventional SAM tones, whereas beats produce significantly smaller responses.

  20. Social web artifacts for boosting recommenders theory and implementation

    CERN Document Server

    Ziegler, Cai-Nicolas


    Recommender systems, software programs that learn from human behavior and make predictions of what products we are expected to appreciate and purchase, have become an integral part of our everyday life. They proliferate across electronic commerce around the globe and exist for virtually all sorts of consumable goods, such as books, movies, music, or clothes. At the same time, a new evolution on the Web has started to take shape, commonly known as the “Web 2.0” or the “Social Web”: Consumer-generated media has become rife, social networks have emerged and are pulling significant shares of Web traffic. In line with these developments, novel information and knowledge artifacts have become readily available on the Web, created by the collective effort of millions of people. This textbook presents approaches to exploit the new Social Web fountain of knowledge, zeroing in first and foremost on two of those information artifacts, namely classification taxonomies and trust networks. These two are used to impr...

  1. Packaging Design. A Systemic Approach to a Complex Artifact

    Directory of Open Access Journals (Sweden)

    Erik Ciravegna


    Full Text Available Packaging is a complex artifact, which has considerably expanded its functions over time. It is an object of use (instrumental prosthesis, which allows to contain the product, protect it, store it, transport it, and at the same time, facilitate its physical interaction with the user. Also, it is communication device (communication prosthesis, characterized by functions, among others, of appellative, persuasive, informative and prescriptive kind. For its multifaceted nature, the project of a package requires different skills and the intervention of multiple disciplines: for that reason, should be understood as the result of an integrated set of choices made by a plurality of actors, where each performs a specific role – direct or indirect – in its definition. These actors, together with the relationships that are established throughout the product life cycle, define the so-called “packaging-system”. Within this system, Design –and specifically Communication Design– may play an important role in direction and mediation, potentially giving shape through the project synthesis to solutions which are an expression of the confluence of the needs of the different parties involved and the multiple functions of the artifact, connecting the communicative dimension to a strictly instrumental dimension.

  2. A convolutional neural network to filter artifacts in spectroscopic MRI. (United States)

    Gurbani, Saumya S; Schreibmann, Eduard; Maudsley, Andrew A; Cordova, James Scott; Soher, Brian J; Poptani, Harish; Verma, Gaurav; Barker, Peter B; Shim, Hyunsuk; Cooper, Lee A D


    Proton MRSI is a noninvasive modality capable of generating volumetric maps of in vivo tissue metabolism without the need for ionizing radiation or injected contrast agent. Magnetic resonance spectroscopic imaging has been shown to be a viable imaging modality for studying several neuropathologies. However, a key hurdle in the routine clinical adoption of MRSI is the presence of spectral artifacts that can arise from a number of sources, possibly leading to false information. A deep learning model was developed that was capable of identifying and filtering out poor quality spectra. The core of the model used a tiled convolutional neural network that analyzed frequency-domain spectra to detect artifacts. When compared with a panel of MRS experts, our convolutional neural network achieved high sensitivity and specificity with an area under the curve of 0.95. A visualization scheme was implemented to better understand how the convolutional neural network made its judgement on single-voxel or multivoxel MRSI, and the convolutional neural network was embedded into a pipeline capable of producing whole-brain spectroscopic MRI volumes in real time. The fully automated method for assessment of spectral quality provides a valuable tool to support clinical MRSI or spectroscopic MRI studies for use in fields such as adaptive radiation therapy planning. © 2018 International Society for Magnetic Resonance in Medicine.

  3. Vitrectorhexis and lens aspiration with posterior chamber intraocular lens implantation in spherophakia. (United States)

    Al-Haddad, Christiane; Khatib, Lama


    We describe a technique that uses the vitrector to perform successful lens aspiration and posterior chamber intraocular lens (IOL) implantation in children with spherophakia and anterior lens subluxation. After an anterior chamber maintainer is placed, the ocutome is introduced through a limbal incision to perform a circular vitrectorhexis to avoid excessive manipulation of the unstable lens followed by gentle cortex aspiration. A foldable IOL is injected into the sulcus (3-piece IOL) or bag (1-piece IOL) if the capsule is sufficiently stable. Through a pars plana incision, the ocutome is then used to perform a posterior capsulotomy to prevent late posterior capsule opacification. In our patient, sulcus IOL placement was more stable than in-the-bag placement. Neither author has a financial or proprietary interest in any material or method mentioned. Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  4. Solar powered desalination system using Fresnel lens (United States)

    Sales, M. T. B. F.


    The Philippines is surrounded by coastal areas and these areas can be a potential source for potable water. This study aims to design and construct a solar powered desalination system using Fresnel lens. The experimental study was conducted using polluted salt water for the sample and desalination was carried out using the designed system. The desalination system was composed of the solar concentrator, solar still and the condenser system. The Fresnel lens was made of acrylic plastic and was an effective solar concentrator. Solar stills made of dark colored glass bottles were effective in absorbing the solar energy. The condenser system made of polybutylene and polystyrene were effective in condensing the vapor at ambient temperature. The shortest time of vaporization of the salt water was at 293 sec and the optimum angle of position of the lens was 36.42°. The amount of condensate collected was directly proportional to the amount of salt water in the solar still. The highest mean efficiency of the designed set-up was 34.82%. The water produced by the solar powered desalination system using Fresnel lens passed the standards set by WHO (World Health Organization) for drinking water.

  5. Electronic states in a quantum lens

    International Nuclear Information System (INIS)

    Rodriguez, Arezky H.; Trallero-Giner, C.; Ulloa, S. E.; Marin-Antuna, J.


    We present a model to find analytically the electronic states in self-assembled quantum dots with a truncated spherical cap (''lens'') geometry. A conformal analytical image is designed to map the quantum dot boundary into a dot with semispherical shape. The Hamiltonian for a carrier confined in the quantum lens is correspondingly mapped into an equivalent operator and its eigenvalues and eigenfunctions for the corresponding Dirichlet problem are analyzed. A modified Rayleigh-Schro''dinger perturbation theory is presented to obtain analytical expressions for the energy levels and wave functions as a function of the spherical cap height b and radius a of the circular cross section. Calculations for a hard wall confinement potential are presented, and the effect of decreasing symmetry on the energy values and eigenfunctions of the lens-shape quantum dot is studied. As the degeneracies of a semicircular geometry are broken for b≠a, our perturbation approach allows tracking of the split states. Energy states and electronic wave functions with m=0 present the most pronounced influence on the reduction of the lens height. The method and expressions presented here can be straightforwardly extended to deal with more general Hamiltonians, including strains and valence-band coupling effects in Group III--V and Group II--VI self-assembled quantum dots

  6. Surgical treatment of hereditary lens subluxations. (United States)

    Ozdek, Sengul; Sari, Ayca; Bilgihan, Kamil; Akata, Fikret; Hasanreisoglu, Berati


    To evaluate the effectiveness and results of pars plana vitreolensectomy approach with transscleral fixation of intraocular lens in hereditary lens subluxations. Fifteen eyes of 9 consecutive patients with a mean age of 12.8+/-6.2 years (6-26 years) with hereditary lens subluxation were operated on and the results were evaluated in a prospective study. Surgery was considered if best spectacle corrected visual acuity (BSCVA) was less than 20/70. All eyes underwent a 2-port pars plana vitreolensectomy and transscleral fixation of an intraocular lens (IOL). The mean follow-up period was 12.6+/-7.5 months (6-22 months). There was no major intraoperative complication. Preoperatively, 8 eyes (53.3%) had a BSCVA of counting fingers (CF) and 7 eyes (46.6%) had a BSCVA of 20/200 to 20/70. Postoperatively, 14 eyes (93.3%) had a BSCVA of 20/50 or better. None of the patients had IOL decentration or intraocular pressure (IOP) increase during the follow-up period. There was a macular hole formation in 1 eye postoperatively. The early results of pars plana vitreolensectomy with IOL implantation using scleral fixation technique had shown that it not only promises a rapid visual rehabilitation but it is also a relatively safe method. More serious complications, however, may occur in the long term.


    African Journals Online (AJOL)

    Reading scripture through a mystical lens. 144 the illuminatory function of scripture which confirms and explains experience, rather than in its philological or scientific status. Elisabeth often juxtaposes several texts when quoting from memory and the biblical foundation of her writings is clearly evident in certain cases which ...

  8. Corneal ring infiltration in contact lens wearers

    Directory of Open Access Journals (Sweden)

    Seyed Ali Tabatabaei


    Full Text Available To report a case of atypical sterile ring infiltrates during wearing soft silicone hydrogel contact lens due to poor lens care. A 29-year-old woman presented with complaints of pain, redness, and morning discharge. She was wearing soft silicone hydrogel contact lens previously; her current symptoms began 1 week before presentation. On examination, best-corrected visual acuity was 20/40 in that eye. Slit-lamp examination revealed dense, ring-shaped infiltrate involving both the superficial and deep stromal layers with lucid interval to the limbus, edema of the epithelium, epithelial defect, and vascularization of the superior limbus. Cornea-specific in vivo laser confocal microscopy (Heidelberg Retina Tomograph 2 Rostock Cornea Module, HRT 2-RCM, Heidelberg Engineering GmbH, Dossenheim, Germany revealed Langerhans cells and no sign of Acanthamoeba or fungal features, using lid scraping and anti-inflammatory drops; her vision completely recovered. We reported an atypical case of a sterile corneal ring infiltrate associated with soft contact lens wearing; smear, culture, and confocal microscopy confirmed a sterile inflammatory reaction.

  9. Properties of the cathode lens combined with a focusing magnetic/immersion-magnetic lens

    Czech Academy of Sciences Publication Activity Database

    Konvalina, Ivo; Müllerová, Ilona


    Roč. 645, č. 1 (2011), s. 55-59 ISSN 0168-9002 R&D Projects: GA ČR GAP102/10/1410; GA AV ČR IAA100650902; GA MŠk ED0017/01/01 Institutional research plan: CEZ:AV0Z20650511 Keywords : cathode lens * compound objective lens * aberration coefficients * spot size * field calculations Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.207, year: 2011

  10. Metal Artifact Reduction Magnetic Resonance Imaging Around Arthroplasty Implants: The Negative Effect of Long Echo Trains on the Implant-Related Artifact. (United States)

    Kumar, Neil M; de Cesar Netto, Cesar; Schon, Lew C; Fritz, Jan


    Long echo train length (ETL) is an often recommended but unproven technique to decrease metal artifacts on magnetic resonance imaging (MRI) scans. Therefore, we quantitatively and qualitatively assessed the effects of ETL on metal artifact on MRI scans using a cobalt-chromium-containing arthroplasty implant system. Using a total ankle arthroplasty system implanted into a human cadaver ankle and a clinical 1.5 T MRI system, turbo spin echo (TSE) pulse sequences were acquired with ETL ranging from 3 to 23 and receiver bandwidth (BW) from 100 to 750 Hz/pixel, whereas effective echo time and spatial resolution were controlled. A compressed sensing slice encoding for metal artifact correction TSE prototype pulse sequence was used as reference standard. End points included the total implant-related artifact area and implant-related signal void areas. Two raters evaluated the overall image quality and preference across varying BW and ETL. Two-factor analysis of variance, Friedman test, Kruskal-Wallis test, and Pearson correlation were used. P values of less than 0.05 were considered statistically significant. The total implant-related artifact area ranged from 0.119 for compressed sensing slice encoding for metal artifact correction (BW, 600 Hz/pixel; ETL, 3) to 0.265 for TSE (BW, 100 Hz/pixel; ETL, 23). Longer ETL significantly increases the total implant-related artifact area (P = 0.0004), whereas it decreased with increasing BW (P train length, but reduced with higher BW (P trains fail to reduce implant-related metal artifacts, but in fact cause degradation of image quality around the implant with resultant larger appearing total metal artifacts.

  11. Intrinsic lens potential of neural retina inhibited by Notch signaling as the cause of lens transdifferentiation. (United States)

    Iida, Hideaki; Ishii, Yasuo; Kondoh, Hisato


    Embryonic neural retinas of avians produce lenses under spreading culture conditions. This phenomenon has been regarded as a paradigm of transdifferentiation due to the overt change in cell type. Here we elucidated the underlying mechanisms. Retina-to-lens transdifferentiation occurs in spreading cultures, suggesting that it is triggered by altered cell-cell interactions. Thus, we tested the involvement of Notch signaling based on its role in retinal neurogenesis. Starting from E8 retina, a small number of crystallin-expressing lens cells began to develop after 20 days in control spreading cultures. By contrast, addition of Notch signal inhibitors to cultures after day 2 strongly promoted lens development beginning at day 11, and a 10-fold increase in δ-crystallin expression level. After Notch signal inhibition, transcription factor genes that regulate the early stage of eye development, Prox1 and Pitx3, were sequentially activated. These observations indicate that the lens differentiation potential is intrinsic to the neural retina, and this potential is repressed by Notch signaling during normal embryogenesis. Therefore, Notch suppression leads to lens transdifferentiation by disinhibiting the neural retina-intrinsic program of lens development. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Evaluation of metal artifacts in clinical MR images of patients with total hip arthroplasty using different metal artifact-reducing sequences. (United States)

    Müller, Gunilla M; Lundin, Björn; von Schewelov, Thord; Müller, Markus F; Ekberg, Olle; Månsson, Sven


    To evaluate the distortion and artifact area of metal in MR images and to compare artifact reduction using different metal artifact-reducing sequences in patients with metal-on-metal (MoM) and non-MoM total hip prostheses. Thirty-six MoM and 15 non-MoM prostheses were examined in a 1.5-T MR scanner using T1-weighted (T1-w) sequences: turbo spin echo (TSE) high-readout bandwidth (hiBW), T1-w; TSE view angle tilting (VAT), T1-w; TSE VAT + slice encoding for metal artifact correction (SEMAC); short tau inversion recovery (STIR) hiBW or matched RF pulses (mRFp). Distortion was quantified using a new method measuring the acetabular roof angle (ARA). The artifact area was defined in the mid-coronal plane of the artifact. The T1 VAT + SEMAC sequence showed the least distortion compared to T1 VAT and T1-hiBW (150°, 127° and 102°, p < 0.001, in MoM; 152°, 143° and 128°, p ≤ 0.014, in non-MoM). The artifact area was smaller in MoM prostheses using the T1 VAT sequence compared to T1 hiBW and T1 VAT + SEMAC (2506 mm(2), 3160 mm(2) and 3214 mm(2), p < 0.001) and smaller in non-MoM prostheses using T1 VAT compared to T1-hiBW (4296 mm(2) and 4831 mm(2), p = 0.041). STIR-mRFp substantially reduced the artifact size compared with STIR-hiBW (MoM 4559 mm(2) and 6323 mm(2); non-MoM 5625 mm(2) and 8764 mm(2), p < 0.001). Metal artifacts in MR imaging examinations of hip prostheses can be evaluated for distortion using a distortion angle (ARA) and the degree of signal artifact as determined by measuring the largest cross-sectional artifact area. T1 VAT + SEMAC showed the least distortion; T1 VAT and STIR-mRFp were most efficient for reduction of the artifact area.

  13. Artifact Elimination Technique in Tomogram of X-ray Computed Tomography

    International Nuclear Information System (INIS)

    Rasif Mohd Zain


    Artifacts of tomogram are main commonly problems occurred in x-ray computed tomography. The artifacts will be appearing in tomogram due to noise, beam hardening, and scattered radiation. The study has been carried out using CdTe time pix detector. The new technique has been developed to eliminate the artifact occurred in hardware and software. The hardware setup involved the careful alignment all of the components of the system and the introduction of a collimator beam. Meanwhile, in software development deal with the flat field correction, noise filter and data projection algorithm. The results show the technique developed produce good quality images and eliminate the artifacts. (author)

  14. Ring artifact reduction in synchrotron x-ray tomography through helical acquisition (United States)

    Pelt, Daniël M.; Parkinson, Dilworth Y.


    In synchrotron x-ray tomography, systematic defects in certain detector elements can result in arc-shaped artifacts in the final reconstructed image of the scanned sample. These ring artifacts are commonly found in many applications of synchrotron tomography, and can make it difficult or impossible to use the reconstructed image in further analyses. The severity of ring artifacts is often reduced in practice by applying pre-processing on the acquired data, or post-processing on the reconstructed image. However, such additional processing steps can introduce additional artifacts as well, and rely on specific choices of hyperparameter values. In this paper, a different approach to reducing the severity of ring artifacts is introduced: a helical acquisition mode. By moving the sample parallel to the rotation axis during the experiment, the sample is detected at different detector positions in each projection, reducing the effect of systematic errors in detector elements. Alternatively, helical acquisition can be viewed as a way to transform ring artifacts to helix-like artifacts in the reconstructed volume, reducing their severity. We show that data acquired with the proposed mode can be transformed to data acquired with a virtual circular trajectory, enabling further processing of the data with existing software packages for circular data. Results for both simulated data and experimental data show that the proposed method is able to significantly reduce ring artifacts in practice, even compared with popular existing methods, without introducing additional artifacts.

  15. Scanning RBS-PIXE study of ancient artifacts from South America using a microbeam (United States)

    Ruvalcaba-Sil, J. L.; Demortier, G.


    Pre-Hispanic goldsmiths developed original techniques to manufacture and to gild ornaments and artifacts. Gold metallurgy in ancient America was mainly a surface technology. Surface studies of artifacts from various regions of pre-Hispanic South America were carried out using a 2 MeV proton microbeam (10 μm diameter). Several regions of the artifacts were scanned: RBS and PIXE were used simultaneously to determine the elemental composition and to characterize the homogeneity in depth and at the surface. Complementary information is provided from previous analyses using a macrobeam. Outstanding aspects about the metallurgical processes involved in the gilding of the artifacts have been established.

  16. What causes the "wet diaper" artifact? computed tomography and magnetic resonance observations. (United States)

    Markowitz, Richard I; Altes, Talissa A; Jaramillo, Diego


    Disposable diapers contain super absorbent polymers that absorb liquid. A radio-dense artifact, seen when the diaper is wet, obscures radiographic information but is frequently misinterpreted. Our purpose was to examine this artifact on CT and MR to further clarify and explain its origin. Dry and wet diapers were imaged. Fluid within the wet diaper appeared as small nodules with characteristics of bound water. No free water was detected. Dry diapers produced no artifact. The artifact is most undesirable on radiographs, but does not obscure diagnostic information on cross-sectional imaging. It should not be misinterpreted as contrast.

  17. Dealing with noise and physiological artifacts in human EEG recordings: empirical mode methods (United States)

    Runnova, Anastasiya E.; Grubov, Vadim V.; Khramova, Marina V.; Hramov, Alexander E.


    In the paper we propose the new method for removing noise and physiological artifacts in human EEG recordings based on empirical mode decomposition (Hilbert-Huang transform). As physiological artifacts we consider specific oscillatory patterns that cause problems during EEG analysis and can be detected with additional signals recorded simultaneously with EEG (ECG, EMG, EOG, etc.) We introduce the algorithm of the proposed method with steps including empirical mode decomposition of EEG signal, choosing of empirical modes with artifacts, removing these empirical modes and reconstructing of initial EEG signal. We show the efficiency of the method on the example of filtration of human EEG signal from eye-moving artifacts.

  18. A fully automatic device for compensating for artifacts in conventional catheter-manometer pressure recordings. (United States)

    Brower, R W; Spaans, W; Rewiersma, P A; Meester, G T


    A device is described which detects the resonant artifacts in clinical cathetermanometer systems and automatically sets a notch filter so as to provide some measure of compensation. The equalised response characteristic does visibly improve transient response by removing resonant artifacts due to the uneven transfer function characteristic in these systems. Artifacts due to knocking of the catheter by the heart, external vibrations induced in the manometer, its mechanical support, or the catheter are reduced, but not eliminated. Nevertheless, the system described here has provided a solution to an important class of artifacts in conventional fluid filled catheter-manometer pressure recordings.

  19. Roadmap grounded as 'visual portray' : Reflecting on an artifact and metaphor

    NARCIS (Netherlands)

    Simonse, W.L.; Buijs, J.A.; Hultink, H.J.


    Artifacts Design representations and presentations of work, strategic thinking, and business processes. Main theme Design!? - related by research program on Design Roadmapping, at the Industrial Design Engineering Faculty.

  20. Nanosecond KTN varifocal lens without electric field induced phase transition (United States)

    Zhu, Wenbin; Chao, Ju-Hung; Chen, Chang-Jiang; Campbell, Adrian; Henry, Michael; Yin, Stuart (Shizhuo); Hoffman, Robert C.


    This paper presents a nanosecond speed KTN varifocal lens. The tuning principle of varifocal lens is based on the high-speed refractive index modulation from the nanosecond speed tunable electric field. A response time on the order of nanoseconds was experimentally demonstrated, which is the fastest varifocal lens reported so far. The results confirmed that the tuning speed of the KTN varifocal lens could be significantly increased by avoiding the electric field induced phase transition. Such a nanosecond speed varifocal lens can be greatly beneficial for a variety of applications that demand high speed axial scanning, such as high-resolution 3D imaging and high-speed 3D printing.

  1. Acid phosphatase and lipid peroxidation in human cataractous lens epithelium

    Directory of Open Access Journals (Sweden)

    Vasavada Abhay


    Full Text Available The anterior lens epithelial cells undergo a variety of degenerative and proliferative changes during cataract formation. Acid phosphatase is primarily responsible for tissue regeneration and tissue repair. The lipid hydroperoxides that are obtained by lipid peroxidation of polysaturated or unsaturated fatty acids bring about deterioration of biological membranes at cellular and tissue levels. Acid phosphatase and lipid peroxidation activities were studied on the lens epithelial cells of nuclear cataract, posterior subcapsular cataract, mature cataract, and mixed cataract. Of these, mature cataractous lens epithelium showed maximum activity for acid phosphatase (516.83 moles of p-nitrophenol released/g lens epithelium and maximum levels of lipid peroxidation (86.29 O.D./min/g lens epithelium. In contrast, mixed cataractous lens epithelium showed minimum activity of acid phosphatase (222.61 moles of p-nitrophenol released/g lens epithelium and minimum levels of lipid peroxidation (54.23 O.D./min/g lens epithelium. From our study, we correlated the maximum activity of acid phosphatase in mature cataractous lens epithelium with the increased areas of superimposed cells associated with the formation of mature cataract. Likewise, the maximum levels of lipid peroxidation in mature cataractous lens epithelium was correlated with increased permeability of the plasma membrane. Conversely, the minimum levels of lipid peroxidation in mixed cataractous lens epithelium makes us presume that factors other than lipid peroxidation may also account for the formation of mixed type of cataract.

  2. The color enhancement and collimation features of the multi-colored LEDs with different periodic microstructure on the top surface of TIR lens (United States)

    Ying, Shang-Ping; Fu, Han-Kuei


    Due to the advantages, such as high efficiency, power consumption reduction, no mercury, pure saturated color, high reliability and long lifetime, the solid-state lighting based on light-emitting diodes (LEDs) has become very popular at this stage. In the lighting applications such as spot lighting, downlighting, architectural and show lighting, the colortunable properties with collimating beam of LEDs are highly demanded. The color-tunable lighting is easily achieved using multi-colored LEDs instead of inefficient color filters. However, the applications of multi-colored LEDs usually appear the undesirable light patterns such as color separation or color fringes. At the meantime, the use of TIR (total internal reflection) lens for multi-colored LEDs to collimate the light from the LEDs with different color will introduce seriously undesirable artifacts. Thus, a periodic microstructure surface on the top surface of the TIR lens would be used to reshape the light from the different colored LED chips in the multi-colored LEDs, and then decrease the color separation and color nonuniformity. In this study, the TIR lens with periodic microstructure surface on the top surface would be used to collimate the light from multi-colored LEDs with low color separation or color fringes. The analysis of color enhancement and collimation features of the multi-colored LEDs with different periodic microstructure on the top surface of the TIR lens is presented.

  3. Oxygen transport through soft contact lens and cornea: Lens characterization and metabolic modeling (United States)

    Chhabra, Mahendra

    The human cornea requires oxygen to sustain metabolic processes critical for its normal functioning. Any restriction to corneal oxygen supply from the external environment (e.g., by wearing a low oxygen-permeability contact lens) can lead to hypoxia, which may cause corneal edema (swelling), limbal hyperemia, neovascularization, and corneal acidosis. The need for adequate oxygen to the cornea is a major driving force for research and development of hypertransmissible soft contact lenses (SCLs). Currently, there is no standard technique for measuring oxygen permeability (Dk) of hypertransmissible silicone-hydrogel SCLs. In this work, an electrochemistry-based polarographic apparatus was designed, built, and operated to measure oxygen permeability in hypertransmissible SCLs. Unlike conventional methods where a range of lens thickness is needed for determining oxygen permeabilities of SCLs, this apparatus requires only a single lens thickness. The single-lens permeameter provides a reliable, efficient, and economic tool for measuring oxygen permeabilities of commercial hypertransmissible SCLs. The single-lens permeameter measures not only the product Dk, but, following modification, it measures separately diffusivity, D, and solubility, k, of oxygen in hypertransmissible SCLs. These properties are critical for designing better lens materials that ensure sufficient oxygen supply to the cornea. Metabolism of oxygen in the cornea is influenced by contact-lens-induced hypoxia, diseases such as diabetes, surgery, and drug treatment, Thus, estimation of the in-vivo corneal oxygen consumption rate is essential for gauging adequate oxygen supply to the cornea. Therefore, we have developed an unsteady-state reactive-diffusion model for the cornea-contact-lens system to determine in-vivo human corneal oxygen-consumption rate. Finally, a metabolic model was developed to determine the relation between contact-lens oxygen transmissibility (Dk/L) and corneal oxygen deficiency. A

  4. Subjective assessment of contact lens wear by army aircrew. (United States)

    Lattimore, M R; Cornum, R L


    Because 23% of Army aviators are ametropic, contact lenses have drawn increased attention as a spectacle substitute to solve system compatibility problems. From November 1988 until October 1991, a series of contact lens research protocols were conducted to develop a comprehensive database on contact lens wear in varied environments. Questionnaires were used to assess suitability and acceptability of routine contact lens wear. Responses from 202 subjects were obtained from September 1989 through September 1991. The questions explored operational and safety of flight issues of contact lens wear. Subjects overwhelmingly approved of contact lens use in all settings: 95% expressed greater combat readiness and effectiveness with contact lenses, 98% felt contact lens use (and maintenance) in the cockpit had no adverse impact on safety of flight, and 98% endorsed the routine use of contact lenses. These data highlight Army aircrew acceptance of contact lens use.

  5. Pars Plana Vitrectomy in Treatment of Lens Injury

    Directory of Open Access Journals (Sweden)

    Remzi Avcı


    Full Text Available Lens injury due to traumas may present as loss of capsule integrity, cataract, lens subluxation, or lens luxation. In addition, lens subluxation and lens luxation may occur in pseudophakic patients due to trauma. Clear corneal, scleral or sclero-corneal phacoemulsification surgery, pars plana vitrectomy, pars plana vitrectomy with phaco-fragmentation, or pars plana vitrectomy with removal through corneal incision techniques are used in the treatment of lens injury due to traumas. Intraocular lens can be implanted in the bag, sulcus, or anterior chamber during the surgery. Depending on the circumstances, scleral fixated intraocular lenses or iris-claw lenses may also be preferred. Rehabilitation of such patients is not of a great concern today, with the advanced level of vitreoretinal surgery and cataract surgery techniques and with the current state of technology. (Turk J Ophthalmol 2013; 43: 51-4

  6. Artifacts in global atmospheric modeling: Two recent examples (United States)

    Lawrence, Mark G.; Landgraf, Jochen; Jöckel, Patrick; Eaton, Brian

    To what extent can we trust the results of global atmospheric models? It is well known that a substantial degree of uncertainty exists in the parameters used in these models, for instance in parameterizations of complex physical processes such as convection and in reaction rates for photochemical models. Anyone familiar with computer work is also well aware of occasional “bugs,” such as an “l” typed where a “j” was intended.However, many newcomers to the field of atmospheric modeling (or other similar Earth systems modeling endeavors) are not yet very familiar with the technical side of modeling, have little or no formal education in computer programming, and are instead expected to learn the art of programming on the job. These researchers are often unaware of some of the types of artifacts that can be generated by the software and hardware they use.

  7. Trail Trees: Living Artifacts (Vivifacts of Eastern North America

    Directory of Open Access Journals (Sweden)

    Nicholas C. Kawa


    Full Text Available Living trees historically modified by human populations, oftentimes referred to as “culturally modified trees” (CMTs, are found throughout the North American landscape. In eastern North America specifically, indigenous populations bent thousands of trees to mark trails, and some of these still exist in the region today. In this article, we present a synthesis of current knowledge on trail trees, including their speculated functions, formation, and selection. We also examine the theoretical implications of these living artifacts (or vivifacts and how they may open new avenues for investigation by archaeologists, environmental historians, and ethnobiologists. To conclude, we make a call for expanded public recognition and documentation of trail trees, discussing the need for their incorporation into forest and park management plans.

  8. Motion artifact suppression: a review of post-processing techniques. (United States)

    Hedley, M; Yan, H


    Patient motion during data acquisition in magnetic resonance imaging causes artifacts in the reconstructed image, which for two-dimensional Fourier transform imaging techniques appear as blurring and ghost repetitions of the moving structures. While the problem with intra-view effects has been effectively addressed using gradient moment nulling techniques, there is no corresponding technique for inter-view effects with equal effectiveness and general applicability. A number of techniques have been proposed for correcting the inter-view effects, and these may be divided into those that minimise the corruption of the data, and those that post-process the data to restore the image. The techniques in the former category are briefly reviewed, then those in the latter category are examined in detail. These are analysed in terms of motion model, model parameter estimation, and data correction.


    Directory of Open Access Journals (Sweden)



    Full Text Available In many of its applications forensic anthropology is a singular discipline, midway between a bare techno-scientific exercise and a militant involvement in overcoming situations marked by human rights violations. Today, riding on an intense and transnational wave of humanitarian sensitivity, forensic anthropology has acquired a significant scientific, moral and media status, and has become a front line scientific-technical practice in the human rights field at the planetary level. This text, which analyzes some of the artifacts with which forensic anthropology represents and works on its object, aims to understand this discipline through the concept of moral technique, which, in my understanding, captures the particular tensions of this form of working for good.

  10. Dental artifacts in the head and neck region:

    DEFF Research Database (Denmark)

    Ladefoged, Claes N.; Hansen, Adam E.; Keller, Sune


    region of patients with dental implants. The purpose of this study was to assess the frequency and magnitude of subsequent PET image distortions following MR-AC. METHODS: A total of 148 PET/MR patients with clear visual signal voids on the attenuation map in the dental region were included in this study......BACKGROUND: In the absence of CT or traditional transmission sources in combined clinical positron emission tomography/magnetic resonance (PET/MR) systems, MR images are used for MR-based attenuation correction (MR-AC). The susceptibility effects due to metal implants challenge MR-AC in the neck...... substituted with soft tissue information. Our inpainting algorithm delineates the outer contour of signal voids breaching the anatomical volume using the non-attenuation-corrected PET image and classifies the inner air regions based on an aligned template of likely dental artifact areas. The reconstructed PET...

  11. Postmortem Aortic Dissection: An Artifact of the Embalming Process. (United States)

    Rae, Guenevere; Husain, Mujtaba; McGoey, Robin; Swartz, William


    Aortic dissection (AD) is a serious condition that affects 3/100,000 individuals a year. Recently, a case report was published describing an embalmed patient with an aortic dissection. The purpose of this study was to examine the frequency of AD among 80 embalmed cadavers and confirm the AD with histopathologic evaluation. In seven cases of grossly identified AD, six were determined to be due to the embalming procedure and only one case of true antemortem AD was confirmed. These results suggest that aortic morphology can be altered by administration of the embalming fluid and that alterations can mimic AD, not only on gross inspection but also on postmortem imaging. Awareness of this embalming artifact may prevent misdiagnosis of an aortic dissection in an embalmed patient, a point particularly useful for autopsy pathology that may include postmortem examination of an embalmed patient. © 2015 American Academy of Forensic Sciences.

  12. Sex differences in jealousy: evolutionary mechanism or artifact of measurement? (United States)

    DeSteno, David; Bartlett, Monica Y; Braverman, Julia; Salovey, Peter


    Two studies are presented that challenge the evidentiary basis for the existence of evolved sex differences in jealousy. In opposition to the evolutionary view, Study I demonstrated that a sex difference in jealousy resulting from sexual versus emotional infidelity is observed only when judgments are recorded using a forced-choice response format. On all other measures, no sex differences were found; both men and women reported greater jealousy in response to sexual infidelity. A second study revealed that the sex difference on the forced-choice measure disappeared under conditions of cognitive constraint. These findings suggest that the sex difference used to support the evolutionary view of jealousy (e.g., D. M. Buss, R. Larsen, D. Westen, & J. Semmelroth, 1992; D. M. Buss et al., 1999) likely represents a measurement artifact resulting from a format-induced effortful decision strategy and not an automatic, sex-specific response shaped by evolution.

  13. Clinical evaluation of TOF versus non-TOF on PET artifacts in simultaneous PET/MR: a dual centre experience

    Energy Technology Data Exchange (ETDEWEB)

    Voert, Edwin E.G.W. ter [University Hospital Zurich, Department of Nuclear Medicine, Zurich (Switzerland); University of Zurich, Zurich (Switzerland); Veit-Haibach, Patrick [University Hospital Zurich, Department of Nuclear Medicine, Zurich (Switzerland); University of Zurich, Zurich (Switzerland); University Hospital Zurich, Department of Diagnostic and Interventional Radiology, Zurich (Switzerland); Ahn, Sangtae [GE Global Research, Niskayuna, NY (United States); Wiesinger, Florian [GE Global Research, Muenchen (Germany); Khalighi, M.M.; Delso, Gaspar [GE Healthcare, Waukesha, WI (United States); Levin, Craig S. [Stanford University, Department of Radiology, Molecular Imaging Program at Stanford, Stanford, CA (United States); Iagaru, Andrei H. [Stanford University, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Stanford, CA (United States); Zaharchuk, Greg [Stanford University, Department of Radiology, Neuroradiology, Stanford, CA (United States); Huellner, Martin [University Hospital Zurich, Department of Nuclear Medicine, Zurich (Switzerland); University of Zurich, Zurich (Switzerland); University Hospital Zurich, Department of Neuroradiology, Zurich (Switzerland)


    Our objective was to determine clinically the value of time-of-flight (TOF) information in reducing PET artifacts and improving PET image quality and accuracy in simultaneous TOF PET/MR scanning. A total 65 patients who underwent a comparative scan in a simultaneous TOF PET/MR scanner were included. TOF and non-TOF PET images were reconstructed, clinically examined, compared and scored. PET imaging artifacts were categorized as large or small implant-related artifacts, as dental implant-related artifacts, and as implant-unrelated artifacts. Differences in image quality, especially those related to (implant) artifacts, were assessed using a scale ranging from 0 (no artifact) to 4 (severe artifact). A total of 87 image artifacts were found and evaluated. Four patients had large and eight patients small implant-related artifacts, 27 patients had dental implants/fillings, and 48 patients had implant-unrelated artifacts. The average score was 1.14 ± 0.82 for non-TOF PET images and 0.53 ± 0.66 for TOF images (p < 0.01) indicating that artifacts were less noticeable when TOF information was included. Our study indicates that PET image artifacts are significantly mitigated with integration of TOF information in simultaneous PET/MR. The impact is predominantly seen in patients with significant artifacts due to metal implants. (orig.)

  14. Spontaneous dislocation of lens bag with acrylic lens after uneventful cataract surgery - unusual complication of cataract surgery. (United States)

    Shah, Mehul A; Shah, Shreya M; Mehta, Ruchir; Shah, Prerna


    Spontaneous dislocation of intraocular lens with bag is rare. We report a case of a 56-year-old male who presented with spontaneous anterior dislocation of an in-the-bag intraocular lens 3 years after manual small incision cataract surgery. He had undergone manual small incision cataract surgery with foldable acrylic intraocular lens implantation, and 18 months after cataract surgery ND: YAG capsulotomy with uneventful post capsulotomy follow-up. 17 months after capsulotomy, the patient presented with sudden decrease of vision. On anterior segment examination, the intraocular lens with bag was dislocated into the anterior chamber. It was managed with intraocular lens explantation with bag, anterior vitrectomy and sclera fixated intraocular lens. Spontaneous intraocular lens dislocation with bag is possible after 1.5 years of uneventful surgery which may be managed using different techniques.

  15. Photoplethysmograph signal reconstruction based on a novel motion artifact detection-reduction approach. Part II: Motion and noise artifact removal. (United States)

    Salehizadeh, S M A; Dao, Duy K; Chong, Jo Woon; McManus, David; Darling, Chad; Mendelson, Yitzhak; Chon, Ki H


    We introduce a new method to reconstruct motion and noise artifact (MNA) contaminated photoplethysmogram (PPG) data. A method to detect MNA corrupted data is provided in a companion paper. Our reconstruction algorithm is based on an iterative motion artifact removal (IMAR) approach, which utilizes the singular spectral analysis algorithm to remove MNA artifacts so that the most accurate estimates of uncorrupted heart rates (HRs) and arterial oxygen saturation (SpO2) values recorded by a pulse oximeter can be derived. Using both computer simulations and three different experimental data sets, we show that the proposed IMAR approach can reliably reconstruct MNA corrupted data segments, as the estimated HR and SpO2 values do not significantly deviate from the uncorrupted reference measurements. Comparison of the accuracy of reconstruction of the MNA corrupted data segments between our IMAR approach and the time-domain independent component analysis (TD-ICA) is made for all data sets as the latter method has been shown to provide good performance. For simulated data, there were no significant differences in the reconstructed HR and SpO2 values starting from 10 dB down to -15 dB for both white and colored noise contaminated PPG data using IMAR; for TD-ICA, significant differences were observed starting at 10 dB. Two experimental PPG data sets were created with contrived MNA by having subjects perform random forehead and rapid side-to-side finger movements show that; the performance of the IMAR approach on these data sets was quite accurate as non-significant differences in the reconstructed HR and SpO2 were found compared to non-contaminated reference values, in most subjects. In comparison, the accuracy of the TD-ICA was poor as there were significant differences in reconstructed HR and SpO2 values in most subjects. For non-contrived MNA corrupted PPG data, which were collected with subjects performing walking and stair climbing tasks, the IMAR significantly

  16. Gravitational Lens Time Delays Using Polarization Monitoring

    Directory of Open Access Journals (Sweden)

    Andrew Biggs


    Full Text Available Gravitational lens time delays provide a means of measuring the expansion of the Universe at high redshift (and therefore in the ‘Hubble flow’ that is independent of local calibrations. It was hoped that many of the radio lenses found in the JVAS/CLASS survey would yield time delays as these were selected to have flat spectra and are dominated by multiple compact components. However, despite extensive monitoring with the Very Large Array (VLA, time delays have only been measured for three of these systems (out of 22. We have begun a programme to reanalyse the existing VLA monitoring data with the goal of producing light curves in polarized flux and polarization position angle, either to improve delay measurements or to find delays for new sources. Here, we present preliminary results on the lens system B1600+434 which demonstrate the presence of correlated and substantial polarization variability in each image.

  17. Complications caused by contact lens wearing. (United States)

    Beljan, Jasna; Beljan, Kristina; Beljan, Zdravko


    Complications in wearing contact lenses are very rare and caused by poor maintenance, over-extended wear and wearing of contact lenses in a polluted environment. Regular control by a professional person can efficiently reduce the number of complications. This paper describes the most common risks factors for complications, and complications of wearing contact lenses with the classification according to the anatomic parts of the eye: eyelids, tear film, limbus, corneal epithelium, corneal stroma and corneal endothelium. Every complication has been described by the characteristic signs and symptoms, etiology and pathology, as well as therapy and prognosis. The paper describes how to select adequate customers as contact lens users, with proper education in order to ensure minimal incidence of complications due to contact lens wear, thus attracting a lot of satisfied and healthy customers.

  18. Effects of Temperature on Hybrid Lens Performance (United States)

    Askins, Steve; Victoria, Marta; Herrero, Rebeca; Domínguez, César; Antón, Ignacio; Sala, Gabriel


    In hybrid Silicone-on-glass Fresnel lenses, an optical silicone is molded onto a glass substrate and forms the Fresnel structure. These lenses offer a cost effective solution as a primary optical element in point-focus concentrator photovoltaic modules, as well as performance advantages. However, these lenses have a high performance variation with temperature due both to the change in index of refraction of silicone as well as to deformations in the facets caused by coefficient of thermal expansion (CTE) mismatch. In this study we perform measurements of the light flux at the focal plane of a family of SOG lenses, varying temperature and lens-to-receiver distances. The effect of varying silicone cure temperature and the depth of the silicone between the lens and the glass substrate on temperature dependence was investigated. A preliminary computer model of this behavior is presented.

  19. A Tribute to Dr. Willy Lens

    Directory of Open Access Journals (Sweden)

    Maarten Vansteenkiste


    Full Text Available Dr. Willy Lens, born on December 10th, 1943, passed away on August 29th, 2014. With his passing, the motivation community has lost a seminal member, a mentor, and a friend. Dr. Lens – a Fellow of the Association for Psychological Science and Founding Fellow of the American Educational Research Association – made fundamental contributions to the study of motivation both through his own work and through his caring and thoughtful mentorship of a large community of scholars. With this tribute, we want to honor Dr. Willy Lens’ significance to psychology and education as well as his positive influence, both personally and professionally, on the lives of dozens of scholars. With his contagious enthusiasm and caring mentorship, Willy was an example for our academic community and with this tribute we express our gratitude for the privilege to have collaborated with him.

  20. Stretched Lens Array Photovoltaic Concentrator Technology Developed (United States)

    Piszczor, Michael F., Jr.; O'Neill, Mark J.


    Solar arrays have been and continue to be the mainstay in providing power to nearly all commercial and government spacecraft. Light from the Sun is directly converted into electrical energy using solar cells. One way to reduce the cost of future space power systems is by minimizing the size and number of expensive solar cells by focusing the sunlight onto smaller cells using concentrator optics. The stretched lens array (SLA) is a unique concept that uses arched Fresnel lens concentrators to focus sunlight onto a line of high-efficiency solar cells located directly beneath. The SLA concept is based on the Solar Concentrator Array with Refractive Linear Element Technology (SCARLET) design that was used on NASA's New Millennium Deep Space 1 mission. The highly successful asteroid/comet rendezvous mission (1998 to 2001) demonstrated the performance and long-term durability of the SCARLET/SLA solar array design and set the foundation for further improvements to optimize its performance.

  1. Intraocular lens implantation in microphthalmic patients. (United States)

    Sinskey, R M; Amin, P; Stoppel, J


    Microphthalmos is a developmental disorder of the eye consisting of a smaller than normal eye. This disorder can present as an isolated condition or associated with other systemic alterations. It is not uncommon for patients with microphthalmos to have congenital cataracts along with other ocular and systemic abnormalities. This paper reports the experience with 11 microphthalmic eyes of seven patients who had primary or secondary intraocular lens (IOL) implantation over a six-year period from 1985 to 1991. In all cases the IOL had a 13.5 mm or 14.0 mm overall diameter and a 6.0 mm or 6.5 mm optic. It was difficult to obtain documentation of objective visual improvement in many of these cases because of the associated nystagmus. However, all patients reported subjective improvements. These results suggest that with proper technique and lens selection microphthalmic patients should be considered for IOL implantation with relative safety and success.

  2. Pulser for the Tevatron electron lens gun

    Energy Technology Data Exchange (ETDEWEB)

    Iouri Terechkine et al.


    To compensate for beam-beam interaction in Tevatron, an ''electron lens'' is considered to be an effective instrument. When a bunch of electrons with energy in the range (10-16) kV is overlapping with a bunch of antiprotons, the resulting focusing force for antiprotons can be adjusted by changing the electron beam current and by profiling its radial distribution. There exist several scenarios of how the system must function. According to one of them, an electron gun that supplies electrons must be fed by voltage pulses that follow with the frequency of antiproton bunches circulating in the Tevatron, which is about 2.5 MHz. To provide focusing tailored for each individual antiproton bunch, a modulator of the gun (pulser) must allow pulse-to-pulse voltage change. This report will cover main approaches to a design of a pulser for use with the gun of the Tevatron Electron Lens.

  3. Intraocular Lens Subluxation in Marfan Syndrome (United States)

    Rodrigo, Bolaños-Jiménez; Paulina, López-Lizárraga E; Francesc, March de R; Eduardo, Telich-Tarriba J; Alejandro, Navas


    Purpose : Ectopia lentis (EL) is a major criteria for the diagnosis of Marfan syndrome, it may vary from an asymptomatic mild displacement to a significant subluxation that places the equator of the lens in the pupillary axis. The purpose of this work is to present the case of a patient with Marfan syndrome who received treatment for subluxation at our institution. Case Report : A 51-year-old female diagnosed with Marfan syndrome presented to the emergency department with bilateral eye redness, foreign body sensation and crusting around the eyes on awakening. She had the following history of cardiac and ophthalmologic complications, including: 1. Lens subluxation 2. High myopia 3. Aortic root dilation, 4. Mitral valve prolapse and 5. Tricuspid insufficiency. Conclusion : The ophthalmological management of Marfan patients is challenging and periodical follow-up is needed. Surgical versus conservative management is controversial, each case needs to be evaluated individually to analyze the risks and benefits of the procedures. PMID:25279020

  4. Sterilization potential of contact lens solutions


    Dada Vijay; Mehta Manoj


    In a dynamic field of Contact Lens Solutions maintenance of high standards of anti-microbial activity is a must Resterilization Activity Time′ is a universally accepted yardstick for such an evaluation. In this study eight brands of indigenous popular solutions alongwith two FDA approved solutions were tested for their sterilization efficacy: Standardized suspensions of Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Aspergillus fumigatus were used for the purpose. ...

  5. Performance of a Be Refractive Lens

    International Nuclear Information System (INIS)

    Smither, R.K.; Khounsary, A.M.; Mancini, D.C.; Saleem, K. Abu


    The performance of a beryllium compound refractive lens (CRL) was tested in the energy range of 11.5 to 8.0 keV. The beryllium refractive lens consists of 50 aligned, 1-mm-diameter, hollow spheres in a solid block of beryllium, 30 mm x 20 mm x 55 mm. The minimum web between each hollow sphere was 0.10 mm. The measured focal length of the lens for x-rays close to the axis of the beam was 147.7 cm +/- 2.0 cm at 10 keV and 120.2 +/- 2.0 cm at 9.1 keV. These values agree well with the theoretical values of 146.6 cm and 121.4 cm, respectively. The diameter of the best focus obtained at 10 keV was 35 μm horizontal and 45 μm vertical. For the modified version of the lens used in the 9.1 keV experiment these values were 25 μm horizontal and 35 μm vertical. The x-ray beam cross section for the 10 keV and the 9.1 keV experiments were 0.50 mm x 0.50 mm and 0.30 mm x 0.30 mm, respectively. The enhancement of the flux (photons per sq. mm) was 50:1 at 10 keV and 80:1 in the 9.1 keV experiment

  6. Archaeology through Computational Linguistics: Inscription Statistics Predict Excavation Sites of Indus Valley Artifacts (United States)

    Recchia, Gabriel L.; Louwerse, Max M.


    Computational techniques comparing co-occurrences of city names in texts allow the relative longitudes and latitudes of cities to be estimated algorithmically. However, these techniques have not been applied to estimate the provenance of artifacts with unknown origins. Here, we estimate the geographic origin of artifacts from the Indus Valley…

  7. Automatic detection and classification of artifacts in single-channel EEG

    DEFF Research Database (Denmark)

    Olund, Thomas; Duun-Henriksen, Jonas; Kjaer, Troels W.


    artifact classes using the selected features. Single-channel (Fp1-F7) EEG recordings are obtained from experiments with 12 healthy subjects performing artifact inducing movements. The dataset was used to construct and validate the model. Both subject-specific and generic implementation, are investigated...

  8. X-ray CT Metal Artifact Reduction Using Wavelet Domain L-0 Sparse Regularization

    NARCIS (Netherlands)

    Mehranian, Abolfazl; Ay, Mohammad Reza; Rahmim, Arman; Zaidi, Habib

    X-ray computed tomography (CT) imaging of patients with metallic implants usually suffers from streaking metal artifacts. In this paper, we propose a new projection completion metal artifact reduction (MAR) algorithm by formulating the completion of missing projections as a regularized inverse

  9. 75 FR 57825 - Culturally Significant Objects Imported for Exhibition Determinations: “Artifacts From Auschwitz... (United States)


    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Artifacts From Auschwitz-Birkenau... of August 28, 2000, I hereby determine that the objects to be included in the exhibition ``Artifacts...), Washington, DC 20522-0505. Dated: September 16, 2010. Ann Stock, Assistant Secretary, Bureau of Educational...

  10. Online Help-Seeking in Communities of Practice: Modeling the Acceptance of Conceptual Artifacts (United States)

    Nistor, Nicolae; Schworm, Silke; Werner, Matthias


    Interactive online help systems are considered to be a fruitful supplement to traditional IT helpdesks, which are often overloaded. They often comprise user-generated FAQ collections playing the role of technology-based conceptual artifacts. Two main questions arise: how the conceptual artifacts should be used, and which factors influence their…

  11. Examining Student Digital Artifacts during a Year-Long Technology Integration Initiative (United States)

    Rodriguez, Prisca M.; Frey, Chris; Dawson, Kara; Liu, Feng; Ritzhaupt, Albert D.


    This study was situated within a year-long, statewide technology integration initiative designed to support technology integration within science, technology, engineering, and math classrooms. It examined the elements used in student artifacts in an attempt to investigate trends in digital artifact creation. Among several conclusions, this…

  12. Evaluation of MRI artifacts at 3 Tesla for 38 commonly used cosmetics. (United States)

    Escher, Kirin; Shellock, Frank G


    To evaluate MRI artifacts at 3-Tesla for 38 commonly used cosmetics. Thirty-eight cosmetics (16, nail polishes; 5, eyeliners; 3, mascaras; 10, eye shadows; 1, lip gloss; 1, body lotion; 1, body glitter, and 1, hair loss concealer) underwent evaluation for MRI artifacts at 3-Tesla. The cosmetics were applied a copper-sulfate-filled, phantom and initially assessed using a "screening" gradient echo (GRE) pulse sequence. Of the 38 different cosmetics, 14 (37%) exhibited artifacts. For these 14 cosmetics, additional characterization of artifacts was performed using a GRE pulse sequence. A qualitative scale was applied to characterize the artifact size. Artifacts were observed, as follows: 2, nail polishes; 5, eyeliners; 3, mascaras; 3, eye shadows; 1, hair loss concealer. Artifact size ranged from small (eye shadow) to very large (hair loss concealer) and tended to be associated with the presence of iron oxide or other metal-based ingredient. Commonly used cosmetics caused artifacts that may create issues if the area of interest is the same as where the cosmetic was applied or if its presence was unknown, thus, potentially causing it to be construed as pathology. Therefore, these findings have important implications for patients referred for MRI examinations. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. An evaluation of three commercially available metal artifact reduction methods for CT imaging

    International Nuclear Information System (INIS)

    Huang, Jessie Y; Kerns, James R; Balter, Peter A; Followill, David S; Mirkovic, Dragan; Howell, Rebecca M; Kry, Stephen F; Nute, Jessica L; Liu, Xinming; Stingo, Francesco C


    Three commercial metal artifact reduction methods were evaluated for use in computed tomography (CT) imaging in the presence of clinically realistic metal implants: Philips O-MAR, GE’s monochromatic gemstone spectral imaging (GSI) using dual-energy CT, and GSI monochromatic imaging with metal artifact reduction software applied (MARs). Each method was evaluated according to CT number accuracy, metal size accuracy, and streak artifact severity reduction by using several phantoms, including three anthropomorphic phantoms containing metal implants (hip prosthesis, dental fillings and spinal fixation rods). All three methods showed varying degrees of success for the hip prosthesis and spinal fixation rod cases, while none were particularly beneficial for dental artifacts. Limitations of the methods were also observed. MARs underestimated the size of metal implants and introduced new artifacts in imaging planes beyond the metal implant when applied to dental artifacts, and both the O-MAR and MARs algorithms induced artifacts for spinal fixation rods in a thoracic phantom. Our findings suggest that all three artifact mitigation methods may benefit patients with metal implants, though they should be used with caution in certain scenarios. (paper)

  14. A robust post-processing workflow for datasets with motion artifacts in diffusion kurtosis imaging. (United States)

    Li, Xianjun; Yang, Jian; Gao, Jie; Luo, Xue; Zhou, Zhenyu; Hu, Yajie; Wu, Ed X; Wan, Mingxi


    The aim of this study was to develop a robust post-processing workflow for motion-corrupted datasets in diffusion kurtosis imaging (DKI). The proposed workflow consisted of brain extraction, rigid registration, distortion correction, artifacts rejection, spatial smoothing and tensor estimation. Rigid registration was utilized to correct misalignments. Motion artifacts were rejected by using local Pearson correlation coefficient (LPCC). The performance of LPCC in characterizing relative differences between artifacts and artifact-free images was compared with that of the conventional correlation coefficient in 10 randomly selected DKI datasets. The influence of rejected artifacts with information of gradient directions and b values for the parameter estimation was investigated by using mean square error (MSE). The variance of noise was used as the criterion for MSEs. The clinical practicality of the proposed workflow was evaluated by the image quality and measurements in regions of interest on 36 DKI datasets, including 18 artifact-free (18 pediatric subjects) and 18 motion-corrupted datasets (15 pediatric subjects and 3 essential tremor patients). The relative difference between artifacts and artifact-free images calculated by LPCC was larger than that of the conventional correlation coefficient (pworkflow improved the image quality and reduced the measurement biases significantly on motion-corrupted datasets (pworkflow was reliable to improve the image quality and the measurement precision of the derived parameters on motion-corrupted DKI datasets. The workflow provided an effective post-processing method for clinical applications of DKI in subjects with involuntary movements.

  15. Review of artifacts associated with transrectal ultrasound: understanding, recognition, and prevention of misinterpretation

    NARCIS (Netherlands)

    Hulsmans, F. J.; Castelijns, J. A.; Reeders, J. W.; Tytgat, G. N.


    Artifacts are inadequate representations of the structures being imaged. Transrectal ultrasound (TRUS) used for evaluating rectal tumors has its own, unique spectrum of artifacts such as (1) pseudomasses (beam thickness: imaging of rectal folds; mirror image: reflection at an intraluminal fluid

  16. Individual and joint expert judgments as reference standards in artifact detection

    NARCIS (Netherlands)

    Verduijn, Marion; Peek, Niels; de Keizer, Nicolette F.; van Lieshout, Erik-Jan; de Pont, Anne-Cornelie J. M.; Schultz, Marcus J.; de Jonge, Evert; de Mol, Bas A. J. M.


    OBJECTIVE: To investigate the agreement among clinical experts in their judgments of monitoring data with respect to artifacts, and to examine the effect of reference standards that consist of individual and joint expert judgments on the performance of artifact filters. DESIGN: Individual judgments

  17. An evaluation of three commercially available metal artifact reduction methods for CT imaging (United States)

    Huang, Jessie Y.; Kerns, James R.; Nute, Jessica L.; Liu, Xinming; Balter, Peter A.; Stingo, Francesco C.; Followill, David S.; Mirkovic, Dragan; Howell, Rebecca M.; Kry, Stephen F.


    Three commercial metal artifact reduction methods were evaluated for use in computed tomography (CT) imaging in the presence of clinically realistic metal implants: Philips O-MAR, GE’s monochromatic gemstone spectral imaging (GSI) using dual-energy CT, and GSI monochromatic imaging with metal artifact reduction software applied (MARs). Each method was evaluated according to CT number accuracy, metal size accuracy, and streak artifact severity reduction by using several phantoms, including three anthropomorphic phantoms containing metal implants (hip prosthesis, dental fillings and spinal fixation rods). All three methods showed varying degrees of success for the hip prosthesis and spinal fixation rod cases, while none were particularly beneficial for dental artifacts. Limitations of the methods were also observed. MARs underestimated the size of metal implants and introduced new artifacts in imaging planes beyond the metal implant when applied to dental artifacts, and both the O-MAR and MARs algorithms induced artifacts for spinal fixation rods in a thoracic phantom. Our findings suggest that all three artifact mitigation methods may benefit patients with metal implants, though they should be used with caution in certain scenarios.

  18. A standardized evaluation of artifacts from metallic compounds during fast MR imaging

    DEFF Research Database (Denmark)

    Murakami, Shumei; Verdonschot, Rinus G; Kataoka, Miyoshi


    OBJECTIVE: Metallic compounds present in the oral and maxillofacial regions (OMR) cause large artifacts during MR scanning. We quantitatively assessed these artifacts embedded within a phantom according to standards set by the American Society for Testing and Materials (ASTM). MATERIALS AND METHO...

  19. Spectral CT metal artifact reduction with an optimization-based reconstruction algorithm (United States)

    Gilat Schmidt, Taly; Barber, Rina F.; Sidky, Emil Y.


    Metal objects cause artifacts in computed tomography (CT) images. This work investigated the feasibility of a spectral CT method to reduce metal artifacts. Spectral CT acquisition combined with optimization-based reconstruction is proposed to reduce artifacts by modeling the physical effects that cause metal artifacts and by providing the flexibility to selectively remove corrupted spectral measurements in the spectral-sinogram space. The proposed Constrained `One-Step' Spectral CT Image Reconstruction (cOSSCIR) algorithm directly estimates the basis material maps while enforcing convex constraints. The incorporation of constraints on the reconstructed basis material maps is expected to mitigate undersampling effects that occur when corrupted data is excluded from reconstruction. The feasibility of the cOSSCIR algorithm to reduce metal artifacts was investigated through simulations of a pelvis phantom. The cOSSCIR algorithm was investigated with and without the use of a third basis material representing metal. The effects of excluding data corrupted by metal were also investigated. The results demonstrated that the proposed cOSSCIR algorithm reduced metal artifacts and improved CT number accuracy. For example, CT number error in a bright shading artifact region was reduced from 403 HU in the reference filtered backprojection reconstruction to 33 HU using the proposed algorithm in simulation. In the dark shading regions, the error was reduced from 1141 HU to 25 HU. Of the investigated approaches, decomposing the data into three basis material maps and excluding the corrupted data demonstrated the greatest reduction in metal artifacts.

  20. How to bring a technical artifact into use: A micro-developmental perspective

    NARCIS (Netherlands)

    Overdijk, Maarten; Van Diggelen, Wouter; Andriessen, Jerry; Kirschner, Paul A.


    In order to understand how technical artifacts are attuned to, interacted with, and shaped in various and varied classrooms, it is necessary to construct detailed accounts of the use of particular artifacts in particular classrooms. This paper presents a descriptive account of how a shared

  1. 3D Prior Image Constrained Projection Completion for X-ray CT Metal Artifact Reduction

    NARCIS (Netherlands)

    Mehranian, Abolfazl; Ay, Mohammad Reza; Rahmim, Arman; Zaidi, Habib


    The presence of metallic implants in the body of patients undergoing X-ray computed tomography (CT) examinations often results insevere streaking artifacts that degrade image quality. In this work, we propose a new metal artifact reduction (MAR) algorithm for 2D fan-beam and 3D cone-beam CT based on


    Energy Technology Data Exchange (ETDEWEB)

    Shu, Yiping [National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Chaoyang District, Beijing 100012 (China); Bolton, Adam S.; Montero-Dorta, Antonio D.; Cornachione, Matthew A.; Zheng, Zheng; Brownstein, Joel R. [Department of Physics and Astronomy, University of Utah, 115 South 1400 East, Salt Lake City, UT 84112 (United States); Mao, Shude [Physics Department and Tsinghua Centre for Astrophysics, Tsinghua University, Beijing 100084 (China); Kochanek, Christopher S. [Department of Astronomy and Center for Cosmology and Astroparticle Physics, Ohio State University, Columbus, OH 43210 (United States); Pérez-Fournon, Ismael; Marques-Chaves, Rui [Instituto de Astrofísica de Canarias, C/Vía Láctea, s/n, E-38205 San Cristóbal de La Laguna, Tenerife (Spain); Oguri, Masamune [Research Center for the Early Universe, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Ménard, Brice, E-mail: [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States)


    We present Hubble Space Telescope F606W-band imaging observations of 21 galaxy-Ly α emitter lens candidates in the Baryon Oscillation Spectroscopic Survey Emission-Line Lens Survey (BELLS) for the GALaxy-Ly α EmitteR sYstems (BELLS GALLERY) survey. Seventeen systems are confirmed to be definite lenses with unambiguous evidence of multiple imaging. The lenses are primarily massive early-type galaxies (ETGs) at redshifts of approximately 0.55, while the lensed sources are Ly α emitters (LAEs) at redshifts from two to three. Although most of the lens systems are well fit by smooth lens models consisting of singular isothermal ellipsoids in an external shear field, a thorough exploration of dark substructures in the lens galaxies is required. The Einstein radii of the BELLS GALLERY lenses are, on average, 60% larger than those of the BELLS lenses because of the much higher source redshifts. This will allow for a detailed investigation of the radius evolution of the mass profile in ETGs. With the aid of the average ∼13× lensing magnification, the LAEs are frequently resolved into individual star-forming knots with a wide range of properties. They have characteristic sizes from less than 100 pc to several kiloparsecs, rest-frame far-UV apparent AB magnitudes from 29.6 to 24.2, and typical projected separations of 500 pc to 2 kpc.

  3. [Congenital lens subluxation: visual acuity outcomes and intraocular lens postoperative position]. (United States)

    Arraes, Caroline; Endriss, Daniela; Lobato, Francisco; Arraes, João; Ventura, Marcelo


    To evaluate the visual acuity outcomes and to investigate the intraocular lens (IOL) and endocapsular ring positions with ultrasound biomicroscopy in 17 eyes of 10 patients with congenital lens subluxation who underwent the same surgical technique, by the same surgeon. The study was performed in the ''Hospital de Olhos de Pernambuco'' and ''Fundação Altino Ventura''. The surgical technique consisted of phacoaspiration with implant of endocapsular ring and intraocular lens with one loop haptic amputated. The age varied from 7 to 22 years. Data on visual acuity (VA) before and after surgery, surgery follow-up period, and complications were analyzed. All patients underwent ultrasound biomicroscopy. The mean follow-up period was 2.8 years. There was a VA improvement in 17 (100%) eyes: in 12 eyes (70.6%) the visual acuity was better than 20/40; 4 (23.5%) ranged from 20/40 to 20/100, and 1 (5.9%) had visual acuity worse than 20/100, however better than the preoperative visual acuity. The posterior capsular opacification occurred in 10 eyes (58.9%). Ultrasound biomicroscopy showed that all IOL were partially decentralized, however without surpassing the pupil border limit. Endocapsular ring position was correct and there was a good capsular support in all cases. The evaluated surgical treatment provided good intraocular lens and endocapsular ring position, with VA improvement Thus, this technique is a viable, effective and safe option for the visual rehabilitation of patients with congenital lens subluxation.

  4. Two families of astrophysical diverging lens models (United States)

    Er, Xinzhong; Rogers, Adam


    In the standard gravitational lensing scenario, rays from a background source are bent in the direction of a foreground lensing mass distribution. Diverging lens behaviour produces deflections in the opposite sense to gravitational lensing, and is also of astrophysical interest. In fact, diverging lensing due to compact distributions of plasma has been proposed as an explanation for the extreme scattering events that produce frequency-dependent dimming of extragalactic radio sources, and may also be related to the refractive radio wave phenomena observed to affect the flux density of pulsars. In this work we study the behaviour of two families of astrophysical diverging lenses in the geometric optics limit, the power law, and the exponential plasma lenses. Generally, the members of these model families show distinct behaviour in terms of image formation and magnification, however the inclusion of a finite core for certain power-law lenses can produce a caustic and critical curve morphology that is similar to the well-studied Gaussian plasma lens. Both model families can produce dual radial critical curves, a novel distinction from the tangential distortion usually produced by gravitational (converging) lenses. The deflection angle and magnification of a plasma lens vary with the observational frequency, producing wavelength-dependent magnifications that alter the amplitudes and the shape of the light curves. Thus, multiwavelength observations can be used to physically constrain the distribution of the electron density in such lenses.

  5. Dynamic metasurface lens based on MEMS technology

    Directory of Open Access Journals (Sweden)

    Tapashree Roy


    Full Text Available In the recent years, metasurfaces, being flat and lightweight, have been designed to replace bulky optical components with various functions. We demonstrate a monolithic Micro-Electro-Mechanical System (MEMS integrated with a metasurface-based flat lens that focuses light in the mid-infrared spectrum. A two-dimensional scanning MEMS platform controls the angle of the lens along two orthogonal axes by ±9°, thus enabling dynamic beam steering. The device could be used to compensate for off-axis incident light and thus correct for aberrations such as coma. We show that for low angular displacements, the integrated lens-on-MEMS system does not affect the mechanical performance of the MEMS actuators and preserves the focused beam profile as well as the measured full width at half maximum. We envision a new class of flat optical devices with active control provided by the combination of metasurfaces and MEMS for a wide range of applications, such as miniaturized MEMS-based microscope systems, LIDAR scanners, and projection systems.

  6. Adaptive Liquid Lens Actuated by Droplet Movement

    Directory of Open Access Journals (Sweden)

    Chao Liu


    Full Text Available In this paper we report an adaptive liquid lens actuated by droplet movement. Four rectangular PMMA (Polymethyl Methacrylate substrates are stacked to form the device structure. Two ITO (Indium Tin Oxide sheets stick on the bottom substrate. One PMMA sheet with a light hole is inserted in the middle of the device. A conductive droplet is placed on the substrate and touches the PMMA sheet to form a small closed reservoir. The reservoir is filled with another immiscible non-conductive liquid. The non-conductive liquid can form a smooth concave interface with the light hole. When the device is applied with voltage, the droplet stretches towards the reservoir. The volume of the reservoir reduces, changing the curvature of the interface. The device can thus achieve the function of an adaptive lens. Our experiments show that the focal length can be varied from −10 to −159 mm as the applied voltage changes from 0 to 65 V. The response time of the liquid lens is ~75 ms. The proposed device has potential applications in many fields such as information displays, imaging systems, and laser scanning systems.

  7. Thin wetting film lens-less imaging

    International Nuclear Information System (INIS)

    Allier, C.P.; Poher, V.; Coutard, J.G.; Hiernard, G.; Dinten, J.M.


    Lens-less imaging has recently attracted a lot of attention as a compact, easy-to-use method to image or detect biological objects like cells, but failed at detecting micron size objects like bacteria that often do not scatter enough light. In order to detect single bacterium, we have developed a method based on a thin wetting film that produces a micro-lens effect. Compared with previously reported results, a large improvement in signal to noise ratio is obtained due to the presence of a micro-lens on top of each bacterium. In these conditions, standard CMOS sensors are able to detect single bacterium, e.g. E. coli, Bacillus subtilis and Bacillus thuringiensis, with a large signal to noise ratio. This paper presents our sensor optimization to enhance the SNR; improve the detection of sub-micron objects; and increase the imaging FOV, from 4.3 mm 2 to 12 mm 2 to 24 mm 2 , which allows the detection of bacteria contained in 0.5 μl to 4 μl to 10 μl, respectively. (authors)

  8. Compound refractive X-ray lens

    International Nuclear Information System (INIS)

    Nygren, D.R.; Cahn, R.; Cederstrom, B.; Danielsson, M.; Vestlund, J.


    An apparatus and method are disclosed for focusing X-rays. In one embodiment, his invention is a commercial-grade compound refractive X-ray lens. The commercial-grade compound refractive X-ray lens includes a volume of low-Z material. The volume of low-Z material has a first surface which is adapted to receive X-rays of commercially-applicable power emitted from a commercial-grade X-ray source. The volume of low-Z material also has a second surface from which emerge the X-rays of commercially-applicable power which were received at the first surface. Additionally, the commercial-grade compound refractive X-ray lens includes a plurality of openings which are disposed between the first surface and the second surface. The plurality of openings are oriented such that the X-rays of commercially-applicable power which are received at the first surface, pass through the volume of low-Z material and through the plurality openings. In so doing, the X-rays which emerge from the second surface are refracted to a focal point

  9. Laboratory Demonstration of Axicon-Lens Coronagraph (United States)

    Choi, Jaeho; Jea, Geonho


    The results of laboratory based experiments of the proposed coronagraph using axicon-lenses that is conjunction with a method of noninterferometric quantitative phase imaging for direct imaging of exoplanets is will present. The light source is passing through tiny holes drilled on the thin metal plate is used as the simulated stellar and its companions. Those diffracted light at the edge of the holes bears a similarity to the light from the bright stellar. Those images are evaginated about the optical axis after the maximum focal length of the first axicon lens. Then the evaginated images of have cut off using the motorized iris which means the suppressed the central stellar light preferentially. Various length between the holes which represent the angular distance are examined. The laboratory experimental results are shown that the axicon-lens coronagraph has feature of ability to achieve the smaller IWA than l/D and high-contrast direct imaging. The laboratory based axicon-lens coronagraph imaging support the symbolic computation results which has potential in direct imaging for finding exoplanet and various astrophysical activities. The setup of the coronagraph is simple to build and is durable to operate. Moreover it can be transported the planets images to a broadband spectrometric instrument that able to investigate the constituent of the planetary system.

  10. Metasurface axicon lens design at visible wavelengths (United States)

    Alyammahi, Saleimah; Zhan, Qiwen


    The emerging field of metasurfaces is promising to realize novel optical devices with miniaturized flat format and added functionalities. Metasurfaces have been demonstrated to exhibit full control of amplitude, phase and polarization of electromagnetic waves. Using the metasurface, the wavefront of light can be manipulated permitting new functionalities such as focusing and steering of the beams and imaging. One optical component which can be designed using metasurfaces is the axicon. Axicons are conical lenses used to convert Gaussian beams into nondiffraction Bessel beams. These unique devices are utilized in different applications ranging from optical trapping and manipulation, medical imaging, and surgery. In this work, we study axicon lens design comprising of planar metasurfaces which generate non-diffracting Bessel beams at visible wavelengths. Dielectric metasurfaces have been used to achieve high efficiency and low optical loss. We measured the spot size of the resulted beams at different planes to demonstrate the non-diffraction properties of the resulted beams. We also investigated how the spot size is influenced by the axicon aperture. Furthermore, we examined the achromatic properties of the designed axicon. Comparing with the conventional lens, the metasurface axicon lens design enables the creation of flat optical device with wide range of depth of focus along its optical axis.

  11. Radiation dose to the eye lens

    DEFF Research Database (Denmark)

    Baun, Christina; Falch Braas, Kirsten; D. Nielsen, Kamilla


    Radiation Dose to the Eye Lens: Does Positioning Really Matter? C. Baun1, K. Falch1, K.D. Nielsen2, S. Shanmuganathan1, O. Gerke1, P.F. Høilund-Carlsen1 1Department of Nuclear Medicine, Odense University Hospital, Odense C, Denmark. 2University College Lillebaelt, Odense, Denmark. Aim: The scan...... field in oncology patients undergoing eyes-to-thighs PET/CT must always include the base of the scull according to department guidelines. The eye lens is sensitive to radiation exposure and if possible it should be avoided to scan the eye. If the patient’s head is kipped backwards during the scan one...... might avoid including the eye in the CT scan without losing sufficient visualization of the scull base. The aim of this study was to evaluate the possibility of decreasing the radiation dose to the eye lens, simply by changing the head position, when doing the PET/CT scan from the base of the scull...

  12. Dynamic metasurface lens based on MEMS technology (United States)

    Roy, Tapashree; Zhang, Shuyan; Jung, Il Woong; Troccoli, Mariano; Capasso, Federico; Lopez, Daniel


    In the recent years, metasurfaces, being flat and lightweight, have been designed to replace bulky optical components with various functions. We demonstrate a monolithic Micro-Electro-Mechanical System (MEMS) integrated with a metasurface-based flat lens that focuses light in the mid-infrared spectrum. A two-dimensional scanning MEMS platform controls the angle of the lens along two orthogonal axes by ±9°, thus enabling dynamic beam steering. The device could be used to compensate for off-axis incident light and thus correct for aberrations such as coma. We show that for low angular displacements, the integrated lens-on-MEMS system does not affect the mechanical performance of the MEMS actuators and preserves the focused beam profile as well as the measured full width at half maximum. We envision a new class of flat optical devices with active control provided by the combination of metasurfaces and MEMS for a wide range of applications, such as miniaturized MEMS-based microscope systems, LIDAR scanners, and projection systems.

  13. Radiation dose to the lens and cataract formation

    International Nuclear Information System (INIS)

    Henk, J.M.; Whitelocke, R.A.F.; Warrington, A.P.; Bessell, E.M.


    The purpose of this work was to determine the radiation tolerance of the lens of the eye and the incidence of radiation-induced lens changes in patients treated by fractionated supervoltage radiation therapy for orbital tumors. Forty patients treated for orbital lymphoma and pseudotumor with tumor doses of 20--40 Gy were studied. The lens was partly shielded using lead cylinders in most cases. The dose to the germinative zone of the lens was estimated by measurements in a tissue equivalent phantom using both film densitometry and thermoluminescent dosimetry. Opthalmological examination was performed at 6 monthly intervals after treatment. The lead shield was found to reduce the dose to the germinative zone of the lens to between 36--50% of the tumor dose for Cobalt beam therapy, and to between 11--18% for 5 MeV x-rays. Consequently, the lens doses were in the range 4.5--30 Gy in 10--20 fractions. Lens opacities first appeared from between 3 and 9 years after irradiation. Impairment of visual acuity ensued in 74% of the patients who developed lens opacities. The incidence of lens changes was strongly dose-related. None was seen after doses of 5 Gy or lower, whereas doses of 16.5 Gy or higher were all followed by lens opacities which impaired visual acuity. The largest number of patients received a maximum lens dose of 15 Gy; in this group the actuarial incidence of lens opacities at 8 years was 57% with visual impairment in 38%. The adult lens can tolerate a total dose of 5 Gy during a fractionated course of supervoltage radiation therapy without showing any changes. Doses of 16.5 Gy or higher will almost invariably lead to visual impairment. The dose which causes a 50% probability of visual impairment is approximately 15 Gy. 10 refs., 4 figs., 1 tab

  14. Effect of pressure and padding on motion artifact of textile electrodes. (United States)

    Cömert, Alper; Honkala, Markku; Hyttinen, Jari


    With the aging population and rising healthcare costs, wearable monitoring is gaining importance. The motion artifact affecting dry electrodes is one of the main challenges preventing the widespread use of wearable monitoring systems. In this paper we investigate the motion artifact and ways of making a textile electrode more resilient against motion artifact. Our aim is to study the effects of the pressure exerted onto the electrode, and the effects of inserting padding between the applied pressure and the electrode. We measure real time electrode-skin interface impedance, ECG from two channels, the motion artifact related surface potential, and exerted pressure during controlled motion by a measurement setup designed to estimate the relation of motion artifact to the signals. We use different foam padding materials with various mechanical properties and apply electrode pressures between 5 and 25 mmHg to understand their effect. A QRS and noise detection algorithm based on a modified Pan-Tompkins QRS detection algorithm estimates the electrode behaviour in respect to the motion artifact from two channels; one dominated by the motion artifact and one containing both the motion artifact and the ECG. This procedure enables us to quantify a given setup's susceptibility to the motion artifact. Pressure is found to strongly affect signal quality as is the use of padding. In general, the paddings reduce the motion artifact. However the shape and frequency components of the motion artifact vary for different paddings, and their material and physical properties. Electrode impedance at 100 kHz correlates in some cases with the motion artifact but it is not a good predictor of the motion artifact. From the results of this study, guidelines for improving electrode design regarding padding and pressure can be formulated as paddings are a necessary part of the system for reducing the motion artifact, and further, their effect maximises between 15 mmHg and 20 mmHg of

  15. Analysis of artifact and infrequent physiological uptake in 18F-FDG PET/CT

    International Nuclear Information System (INIS)

    Li Tianran; Zhao Chunlei; Qian Gennian; Chen Ziqian; Wang Kaitang; You Xueyu; Zheng Chunyu


    Objective: To explore the artifact and infrequent physiological uptake in PET/CT with its imaging and formation features. Methods: The data of PET/CT imaging were retrospectively analyzed and classified based on their cause. Besides, the infrequent physiological uptakes were also analyzed. Results: Artifacts could be classified into natural and technological causes. In natural causes, respiratory movement and high-density matters artifacts were frequently found, whereas in technological cause, the truncation, radioactive leakage and pollution commonly appeared. Infrequent physiological uptakes included uterine endometrium, breast and fat uptakes. Conclusions: The imaging features of artifact in PET can be divided into 'hot' or 'cold' area while infrequent physiological uptakes mainly are 'hot' area. Among the cause of artifact formation, CT-based attenuation corrected physical factor is the commonest. The infrequent physiological uptake somewhat relates to technological error. (authors)

  16. A Framework for the Assessment of Temporal Artifacts in Medium Frame-Rate Binary Video Halftones

    Directory of Open Access Journals (Sweden)

    Rehman Hamood-Ur


    Full Text Available Display of a video having a higher number of bits per pixel than that available on the display device requires quantization prior to display. Video halftoning performs this quantization so as to reduce visibility of certain artifacts. In many cases, visibility of one set of artifacts is decreased at the expense of increasing the visibility of another set. In this paper, we focus on two key temporal artifacts, flicker and dirty-window-effect, in binary video halftones. We quantify the visibility of these two artifacts when the video halftone is displayed at medium frame rates (15 to 30 frames per second. We propose new video halftoning methods to reduce visibility of these artifacts. The proposed contributions are (1 an enhanced measure of perceived flicker, (2 a new measure of perceived dirty-window-effect, (3 a new video halftoning method to reduce flicker, and (4 a new video halftoning method to reduce dirty-window-effect.

  17. Artifacts, intentions, and contraceptives: the problem with having a plan B for plan B. (United States)

    Reed, Philip A


    It is commonly proposed that artifacts cannot be understood without reference to human intentions. This fact, I contend, has relevance to the use of artifacts in intentional action. I argue that because artifacts have intentions embedded into them antecedently, when we use artifacts we are sometimes compelled to intend descriptions of our actions that we might, for various reasons, be inclined to believe that we do not intend. I focus this argument to a specific set of artifacts, namely, medical devices, before considering an extended application to emergency contraceptive devices. Although there is some debate about whether emergency contraception has an abortifacient effect, I argue that if there is an abortifacient effect, then the effect cannot normally be a side effect of one's action.

  18. Filtration of human EEG recordings from physiological artifacts with empirical mode method (United States)

    Grubov, Vadim V.; Runnova, Anastasiya E.; Khramova, Marina V.


    In the paper we propose the new method for dealing with noise and physiological artifacts in experimental human EEG recordings. The method is based on analysis of EEG signals with empirical mode decomposition (Hilbert-Huang transform). We consider noises and physiological artifacts on EEG as specific oscillatory patterns that cause problems during EEG analysis and can be detected with additional signals recorded simultaneously with EEG (ECG, EMG, EOG, etc.) We introduce the algorithm of the method with following steps: empirical mode decomposition of EEG signal, choosing of empirical modes with artifacts, removing empirical modes with artifacts, reconstruction of the initial EEG signal. We test the method on filtration of experimental human EEG signals from eye-moving artifacts and show high efficiency of the method.

  19. Renal streaky artifact during contrast-enhanced abdominal and pelvic CT: Comparison of high versus low osmolality contrast media

    International Nuclear Information System (INIS)

    Kim, Dae Hong; Kim, Jong Chul; Lee, Chung Keun; Shin, Kyoung Suk


    Introduction of low osmolality contrast agent(LOCA) has allowed safer, more comfortable contrast-enhanced CT examination, but there has been significant increase in image degradation when evaluating the kidneys due to streaky artifact. The authors reviewed findings of contrast- enhanced abdominal and pelvic computed tomography(CT) to know the difference of renal streaky artifact between a high osmolality contrast agent (HOCA) and LOCA. This study included two hundred contrast-enhanced CT in 200 patients, 100 performed with HOCA(meglumine ioglicate, 150 ml) and 100 performed with LOCA (iopromide,150 ml). The severity of renal streaky artifact was compared between HOCA and LOCA groups. Of the scans performed with HOCA, 40 had no artifact, 52 had grade I artifact, 6 had grade II artifact, and 2 had grade III artifact. Of the scans preformed with LOCA, 23 had no artifact, 44 had grade I artifact, 29 had grade II artifact, and 4 had grade III artifact. There was significant difference in the degree of the streaky artifact depending upon the osmolality of the contrast media used(by χ 2 -test, P=.0001). The results of this study revealed a statistically significant increased incidence of artifacts and distortions of renal image with LOCA when compared with HOCA

  20. Image statistics and nonlinear artifacts in composed transmission x-ray tomography

    International Nuclear Information System (INIS)

    Duerinckx, A.J.G.


    Knowledge of the image quality and image statistics in Computed Tomography (CT) images obtained with transmission x-ray CT scanners can increase the amount of clinically useful information that can be retrieved. Artifacts caused by nonlinear shadows are strongly object-dependent and are visible over larger areas of the image. No simple technique exists for their complete elimination. One source of artifacts in the first order statistics is the nonlinearities in the measured shadow or projection data used to reconstruct the image. One of the leading causes is the polychromaticity of the x-ray beam used in transmission CT scanners. Ways to improve the resulting image quality and techniques to extract additional information using dual energy scanning are discussed. A unique formalism consisting of a vector representation of the material dependence of the photon-tissue interactions is generalized to allow an in depth analysis. Poly-correction algorithms are compared using this analytic approach. Both quantum and detector electronic noise decrease the quality or information content of first order statistics. Preliminary results are presented using an heuristic adaptive nonlinear noise filter system for projection data. This filter system can be improved and/or modified to remove artifacts in both first and second order image statistics. Artifacts in the second order image statistics arise from the contribution of quantum noise. This can be described with a nonlinear detection equivalent model, similar to the model used to study artifacts in first order statistics. When analyzing these artifacts in second order statistics, one can divide them into linear artifacts, which do not present any problem of interpretation, and nonlinear artifacts, referred to as noise artifacts. A study of noise artifacts is presented together with a discussion of their relative importance in diagnostic radiology

  1. Metal artifact reduction in MRI-based cervical cancer intracavitary brachytherapy (United States)

    Rao, Yuan James; Zoberi, Jacqueline E.; Kadbi, Mo; Grigsby, Perry W.; Cammin, Jochen; Mackey, Stacie L.; Garcia-Ramirez, Jose; Goddu, S. Murty; Schwarz, Julie K.; Gach, H. Michael


    Magnetic resonance imaging (MRI) plays an increasingly important role in brachytherapy planning for cervical cancer. Yet, metal tandem, ovoid intracavitary applicators, and fiducial markers used in brachytherapy cause magnetic susceptibility artifacts in standard MRI. These artifacts may impact the accuracy of brachytherapy treatment and the evaluation of tumor response by misrepresenting the size and location of the metal implant, and distorting the surrounding anatomy and tissue. Metal artifact reduction sequences (MARS) with high bandwidth RF selective excitations and turbo spin-echo readouts were developed for MRI of orthopedic implants. In this study, metal artifact reduction was applied to brachytherapy of cervical cancer using the orthopedic metal artifact reduction (O-MAR) sequence. O-MAR combined MARS features with view angle tilting and slice encoding for metal artifact correction (SEMAC) to minimize in-plane and through-plane susceptibility artifacts. O-MAR improved visualization of the tandem tip on T2 and proton density weighted (PDW) imaging in phantoms and accurately represented the diameter of the tandem. In a pilot group of cervical cancer patients (N  =  7), O-MAR significantly minimized the blooming artifact at the tip of the tandem in PDW MRI. There was no significant difference observed in artifact reduction between the weak (5 kHz, 7 z-phase encodes) and medium (10 kHz, 13 z-phase encodes) SEMAC settings. However, the weak setting allowed a significantly shorter acquisition time than the medium setting. O-MAR also reduced susceptibility artifacts associated with metal fiducial markers so that they appeared on MRI at their true dimensions.

  2. Novel Scanning Lens Instrument for Evaluating Fresnel Lens Performance: Equipment Development and Initial Results (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Herrero, R.; Miller, D. C.; Kurtz, S. R.; Anton, I.; Sala, G.


    A system dedicated to the optical transmittance characterization of Fresnel lenses has been developed at NREL, in collaboration with the UPM. The system quantifies the optical efficiency of the lens by generating a performance map. The shape of the focused spot may also be analyzed to understand change in the lens performance. The primary instrument components (lasers and CCD detector) have been characterized to confirm their capability for performing optical transmittance measurements. Measurements performed on SoG and PMMA lenses subject to a variety of indoor conditions (e.g., UV and damp heat) identified differences in the optical efficiency of the evaluated lenses, demonstrating the ability of the Scanning Lens Instrument (SLI) to distinguish between the aged lenses.

  3. Cryo-Fracturing and Cryo-Planing for In-Lens Cryo-SEM, Using a Newly Designed Diamond Knife (United States)

    Walther, Paul


    High-pressure frozen rat pancreas tissue samples were cryo-fractured and cryo-sectioned with a diamond knife in the microtome of a freeze-etching device. The bulk fracture faces and block faces were investigated in the frozen-hydrated state by use of a cryo-stage in an in-lens SEM. With this combination, relevant biological structures can be investigated with a few nanometers resolution in a near lifelike state, preventing the artifacts of conventional fixation techniques. Compared to TEM replica techniques, the presented method is more versatile since no replica cleaning is necessary. Additional structures can be made visible by controlled sublimation of ice, leading to a better understanding of the three-dimensional organization of organelles, such as the endoplasmic reticulum.

  4. A high excitation magnetic quadrupole lens quadruplet incorporating a single octupole lens for a low spherical aberration probe forming lens system (United States)

    Dou, Yanxin; Jamieson, David N.; Liu, Jianli; Li, Liyi


    This paper describes the design of a new probe forming lens system consisting of a high excitation magnetic quadrupole lens quadruplet that incorporates a single magnetic octupole lens. This system achieves both a high demagnification and a low spherical aberration compared to conventional high excitation systems and is intended for deployment for the Harbin 300 MeV proton microprobe for applications in space science and ion beam therapy. This relative simplicity of the ion optical design to include a single octupole lens minimizes the risks associated with the constructional and operational precision usually needed for the probe forming lens system and this system could also be deployed in microprobe systems that operate with less magnetically rigid ions. The design of the new system is validated with reference to two independent ion optical computer codes.

  5. The neutron silicon lens. An update of the thermal neutron lens results

    International Nuclear Information System (INIS)

    Johnson, M.W.; Daymond, M.R.


    This paper introduces the concept of the Neutron Silicon Lens (NSL) and provides and update on the experimental results achieved to date. The NSL design is a cylindrical neutron lens based on the use of multiple neutron mirrors supported and separated by silicon wafers. Such lenses would have many applications in both the primary and scattered beams on neutron instruments, and would lead to immediate improvements where the sample to be illuminated is small, as in high pressure or engineering strain scanning instruments. (author)

  6. Forensic Analysis of a Contact Lens in a Murder Case. (United States)

    Zwerling, Charles S


    Contact lenses have had rare relevance in trials and/or investigations. After 5 years of burial, orbital remnants were retrieved from an exhumed body and subsequently identified as a key piece of material evidence in a murder trial. The exhumed case materials were evaluated under laboratory conditions and were determined to be contact lens remnants. Contact lens fracture and burial simulation studies were performed to provide additional corroboration of the physical findings of the exhumed contact lens remnants. This material evidence was instrumental in providing factual proof refuting the defendant's testimony in the murder trial. A brief history of contact lens composition and use is provided for understanding the methods and observational results. This forensic case study represents the first published documentation of a contact lens from an exhumed body being used in a murder investigation and establishes an operational procedure for future forensic contact lens examinations. © 2016 American Academy of Forensic Sciences.

  7. Signal processing methods for reducing artifacts in microelectrode brain recordings caused by functional electrical stimulation. (United States)

    Young, D; Willett, F; Memberg, W D; Murphy, B; Walter, B; Sweet, J; Miller, J; Hochberg, L R; Kirsch, R F; Ajiboye, A B


    Functional electrical stimulation (FES) is a promising technology for restoring movement to paralyzed limbs. Intracortical brain-computer interfaces (iBCIs) have enabled intuitive control over virtual and robotic movements, and more recently over upper extremity FES neuroprostheses. However, electrical stimulation of muscles creates artifacts in intracortical microelectrode recordings that could degrade iBCI performance. Here, we investigate methods for reducing the cortically recorded artifacts that result from peripheral electrical stimulation. One participant in the BrainGate2 pilot clinical trial had two intracortical microelectrode arrays placed in the motor cortex, and thirty-six stimulating intramuscular electrodes placed in the muscles of the contralateral limb. We characterized intracortically recorded electrical artifacts during both intramuscular and surface stimulation. We compared the performance of three artifact reduction methods: blanking, common average reference (CAR) and linear regression reference (LRR), which creates channel-specific reference signals, composed of weighted sums of other channels. Electrical artifacts resulting from surface stimulation were 175  ×  larger than baseline neural recordings (which were 110 µV peak-to-peak), while intramuscular stimulation artifacts were only 4  ×  larger. The artifact waveforms were highly consistent across electrodes within each array. Application of LRR reduced artifact magnitudes to less than 10 µV and largely preserved the original neural feature values used for decoding. Unmitigated stimulation artifacts decreased iBCI decoding performance, but performance was almost completely recovered using LRR, which outperformed CAR and blanking and extracted useful neural information during stimulation artifact periods. The LRR method was effective at reducing electrical artifacts resulting from both intramuscular and surface FES, and almost completely restored iBCI decoding

  8. Signal processing methods for reducing artifacts in microelectrode brain recordings caused by functional electrical stimulation (United States)

    Young, D.; Willett, F.; Memberg, W. D.; Murphy, B.; Walter, B.; Sweet, J.; Miller, J.; Hochberg, L. R.; Kirsch, R. F.; Ajiboye, A. B.


    Objective. Functional electrical stimulation (FES) is a promising technology for restoring movement to paralyzed limbs. Intracortical brain-computer interfaces (iBCIs) have enabled intuitive control over virtual and robotic movements, and more recently over upper extremity FES neuroprostheses. However, electrical stimulation of muscles creates artifacts in intracortical microelectrode recordings that could degrade iBCI performance. Here, we investigate methods for reducing the cortically recorded artifacts that result from peripheral electrical stimulation. Approach. One participant in the BrainGate2 pilot clinical trial had two intracortical microelectrode arrays placed in the motor cortex, and thirty-six stimulating intramuscular electrodes placed in the muscles of the contralateral limb. We characterized intracortically recorded electrical artifacts during both intramuscular and surface stimulation. We compared the performance of three artifact reduction methods: blanking, common average reference (CAR) and linear regression reference (LRR), which creates channel-specific reference signals, composed of weighted sums of other channels. Main results. Electrical artifacts resulting from surface stimulation were 175  ×  larger than baseline neural recordings (which were 110 µV peak-to-peak), while intramuscular stimulation artifacts were only 4  ×  larger. The artifact waveforms were highly consistent across electrodes within each array. Application of LRR reduced artifact magnitudes to less than 10 µV and largely preserved the original neural feature values used for decoding. Unmitigated stimulation artifacts decreased iBCI decoding performance, but performance was almost completely recovered using LRR, which outperformed CAR and blanking and extracted useful neural information during stimulation artifact periods. Significance. The LRR method was effective at reducing electrical artifacts resulting from both intramuscular and surface FES, and

  9. Lens regeneration in mice under the influence of vitamin A

    Indian Academy of Sciences (India)

    The effect of vitamin A has been studied on lens regeneration in young (7 days old) as well as adult mice. A longitudinal slit was made under local anesthesia in the cornea over the lens. The lens was extracted intact through the incision. Intraperitonial injection of vitamin A (0.05 ml of 30 IU/ml in young and 0.05 ml of 50 ...

  10. Subcontact Lens Bubble Formation under Low Atmospheric Pressure Conditions. (United States)


    of subcontact lens bubble formation under scleral lenses at altitudes greater than 18,000 ft. Later, after many advances in contact lens fitting and...Reported here are the results of contact lens bubble studies with soft hydrophilic nd rigid gas-permeable lenses . Testing was accomplished in simulated...ccurred at altitudes greater than 20,000 ft. For soft contact lenses , bubble formation was etected in 22 of 92 eyes tested, and occurred at altitudes

  11. Analysis of phakic before intraocular lens implantation for fundus examination


    Juan Chen; Zhong-Ping Chen; Rui-Ling Zhu


    AIM:To investigate the findings of the eyes which were examined preoperatively by three mirror contact lens before the implantation of implantable collamer lens(ICL). To analysis the retinal pathological changes and to explore the clinical analysis of early diagnosis and treatment in retinopathy on fundus examination before operation. METHODS:The retrospective case series study included 127 eyes of 64 patients who underwent phakic intraocular lens implantation were received the fundus examina...

  12. Haemophilus influenzae corneal ulcer in a therapeutic contact lens wearer.


    Armstrong, J. R.; Cohen, K. L.; McCarthy, L. R.


    Haemophilus influenzae is an unusual corneal pathogen and an unusual cause of corneal ulcers in Western society. In previous reports corneal complications from H. influenzae have been secondary to a conjunctivitis. The first case of a primary H. influenzae corneal ulcer as a complication of therapeutic contact lens wear is presented. Since other uncommon bacteria have been reported as causes of contact lens related corneal ulcers, the bacteriology of contact lens related corneal ulcers is rev...

  13. Disposable contact lenses vs. contact lens maintenance for extended wear. (United States)

    Josephson, J E; Caffery, B E; Campbell, I; Slomovic, A R


    We compared a disposable extended wear contact lens modality with conventional extended wear over a 6-week period. To do so, we refit 31 patients who had successfully worn conventional extended wear contact lenses for more than 1 year. One eye was fit with the AcuvueR disposable contact lens, and a new extended wear lens of the type the patient had been wearing was placed on the other eye. At weekly intervals the disposable lens was discarded and a new disposable lens inserted. At the same time, the conventional lens on the fellow eye was cleaned, disinfected, and reinserted. After 6 weeks the ocular response, subjective impressions, and condition of the lenses in the two eyes were compared. Both lenses were then cultured. Three subjects had to discontinue disposable lens wear because of adverse reactions to trapped cellular debris and corneal microcysts. Although the results were not statistically significant, the Acuvue lens appeared to perform better than or equal to the conventional lens in biomicroscopic observation, visual acuity measurement, and subjective patient preference. Eighty-seven percent of patients preferred to continue with the disposable system. There were no differences found in the type or degree of microbial contamination of the lenses.

  14. Further studies of contact lens motion during blinking. (United States)

    Conway, H D; Knoll, H A


    Contact lens motion is felt to be of increasing importance in connection with debris elimination, particularly in extended wear lenses. Thus an improved analysis is made of a simple model for investigating the initial motion of a hard contact lens over the eye during blinking. It is shown that the assumption of constant tear film thickness is a reasonable one. This greatly simplifies the analysis. Various vertical force vs. time variations are considered and lens velocity/time graphs and maximum lens displacement calculated. These are in good agreement with the results of experiment.

  15. Geometry-invariant gradient refractive index lens: analytical ray tracing. (United States)

    Bahrami, Mehdi; Goncharov, Alexander V


    A new class of gradient refractive index (GRIN) lens is introduced and analyzed. The interior iso-indicial contours mimic the external shape of the lens, which leads to an invariant geometry of the GRIN structure. The lens model employs a conventional surface representation using a coincoid of revolution with a higher-order aspheric term. This model has a unique feature, namely, it allows analytical paraxial ray tracing. The height and the angle of an arbitrary incident ray can be found inside the lens in a closed-form expression, which is used to calculate the main optical characteristics of the lens, including the optical power and third-order monochromatic aberration coefficients. Moreover, due to strong coupling of the external surface shape to the GRIN structure, the proposed GRIN lens is well suited for studying accommodation mechanism in the eye. To show the power of the model, several examples are given emphasizing the usefulness of the analytical solution. The presented geometry-invariant GRIN lens can be used for modeling and reconstructing the crystalline lens of the human eye and other types of eyes featuring a GRIN lens.

  16. Particle swarm optimization applied to automatic lens design (United States)

    Qin, Hua


    This paper describes a novel application of Particle Swarm Optimization (PSO) technique to lens design. A mathematical model is constructed, and merit functions in an optical system are employed as fitness functions, which combined radiuses of curvature, thicknesses among lens surfaces and refractive indices regarding an optical system. By using this function, the aberration correction is carried out. A design example using PSO is given. Results show that PSO as optical design tools is practical and powerful, and this method is no longer dependent on the lens initial structure and can arbitrarily create search ranges of structural parameters of a lens system, which is an important step towards automatic design with artificial intelligence.

  17. [Phacoemulsification of subluxated lens with capsular tension ring implantation]. (United States)

    Dorecka, Mariola; Rokicki, Wojciech; Nita, Malgorzata; Krysik, Katarzyna; Nita, Ewa; Sikorska, Aleksandra; Romaniuk, Wanda


    To evaluate long term results of phacoemulsification with PC IOL and capsular tension ring (CTR) implantation in lens subluxation. The study comprised of 134 patients--146 eyes with subluxated lens. In all cases phacoemulsification with PC IOL and CTR implantation was performed. No intaroperative complications has occured. Postoperative complications included: inflammation in the anterior chamber in 3 eyes (2.1%), retinal detachment in 2 eyes (1.4%). In all cases there was no PC IOL decentration. (1) CTR facilitates phacoemulsification with PC IOL implantation in lens subluxation. (2) Phacoemulsification of subluxated lens with PC IOL and CTR implantation seems to be safe and effective procedure.

  18. Acoustic Luneburg lens using orifice-type metamaterial unit cells (United States)

    Park, Choon Mahn; Lee, Sang Hun


    A two-dimensional acoustic Luneburg lens that can be easily expanded into a three-dimensional sphere is fabricated. The required spatial distribution of the refractive index for this Luneburg lens is realized using the characteristics of orifice-type metamaterial unit cells. Typical characteristics of the resulting acoustic Luneburg lens, such as its aberration-free performance and capability for antipodal focusing of the lens for the incident plane waves, are investigated through experiments and simulations with the attenuation loss at frequencies that satisfy the homogeneous medium condition of the metamaterial. With the designed metamaterial, we achieved the minimum spot that lies within the classical diffraction limit at the focal point.

  19. Improved field-mapping and artifact correction in multispectral imaging. (United States)

    Quist, Brady; Shi, Xinwei; Weber, Hans; Hargreaves, Brian A


    To develop a method for improved B 0 field-map estimation, deblurring, and image combination for multispectral imaging near metal. A goodness-of-fit field-map estimation technique is proposed that uses only the multispectral imaging (MSI) data to estimate the field map. Using the improved field map, a novel deblurring technique is proposed that also employs a new image combination scheme to reduce the effects of noise and other residual MSI artifacts. The proposed field-map estimation and deblurring techniques are compared to the current methods in phantoms and/or in vivo from subjects with knee, hip, and spinal metallic implants. Phantom experiments validate that the goodness-of-fit field-map estimation is less sensitive to noise and bias than the conventional center-of-mass technique, which reduces distortion in the deblurring methods. The new deblurring approach also is substantially less sensitive to noise and distortion than the current deblurring method, as demonstrated in phantoms and in vivo, and is able to find a good tradeoff between deblurring and distortion. The proposed methods not only enable field-mapping with reduced noise sensitivity but are able to create deblurred images with less distortion and better signal-to-noise ratio with no additional scan time, thereby enabling improved visualization of underlying anatomy near metallic implants. Magn Reson Med 78:2022-2034, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  20. Automatic detection of artifacts in converted S3D video (United States)

    Bokov, Alexander; Vatolin, Dmitriy; Zachesov, Anton; Belous, Alexander; Erofeev, Mikhail


    In this paper we present algorithms for automatically detecting issues specific to converted S3D content. When a depth-image-based rendering approach produces a stereoscopic image, the quality of the result depends on both the depth maps and the warping algorithms. The most common problem with converted S3D video is edge-sharpness mismatch. This artifact may appear owing to depth-map blurriness at semitransparent edges: after warping, the object boundary becomes sharper in one view and blurrier in the other, yielding binocular rivalry. To detect this problem we estimate the disparity map, extract boundaries with noticeable differences, and analyze edge-sharpness correspondence between views. We pay additional attention to cases involving a complex background and large occlusions. Another problem is detection of scenes that lack depth volume: we present algorithms for detecting at scenes and scenes with at foreground objects. To identify these problems we analyze the features of the RGB image as well as uniform areas in the depth map. Testing of our algorithms involved examining 10 Blu-ray 3D releases with converted S3D content, including Clash of the Titans, The Avengers, and The Chronicles of Narnia: The Voyage of the Dawn Treader. The algorithms we present enable improved automatic quality assessment during the production stage.

  1. High temperature viscoplastic ratchetting: Material response or modeling artifact

    International Nuclear Information System (INIS)

    Freed, A.D.


    Ratchetting, the net accumulation of strain over a loading cycle, is a deformation mechanism that leads to distortions in shape, often resulting in a loss of function that culminates in structural failure. Viscoplastic ratchetting is prevalent at high homologous temperatures where viscous characteristics are prominent in material response. This deformation mechanism is accentuated by the presence of a mean stress; a consequence of interaction between thermal gradients and structural constraints. Favorable conditions for viscoplastic ratchetting exist in the Stirling engines being developed by the National Aeronautics and Space Administration (NASA) and the Department of Energy (DOE) for space and terrestrial power applications. To assess the potential for ratchetting and its effect on durability of high temperature structures requires a viscoplastic analysis of the design. But ratchetting is a very difficult phenomenon to accurately model. One must therefore ask whether the results from such an analysis are indicative of actual material behavior, or if they are artifacts of the theory being used in the analysis. There are several subtle aspects in a viscoplastic model that must be dealt with in order to accurately model ratchetting behavior, and therefore obtain meaningful predictions from it. In this paper, some of these subtlties and the necessary ratchet experiments needed to obtain an accurate viscoplastic representation of a material are discussed

  2. Solvent selection for fatty acid residue analysis of archeologicial artifacts

    Directory of Open Access Journals (Sweden)

    Rosentreter Jeffrey J.


    Full Text Available Residue analysis has rapidly become one of the most useful techniques for determining an artifact function and revealing insight into paleodiets. The success of analytical residue analysis often lies with the first preparatory step, where the residue is extracted from the object. Detection of a residue requires effective solvation of the material, and there is a large range of potential solvents. One purpose of this study is to determine the efficiency of various solvents for the extraction of fatty acids from charcoal, a material that is ubiquitous, easily identified, remarkably stable in the archaeological record but, most importantly for this research, retains fats extremely well. This investigation examines the removal efficiency of model fatty acids from carbonized wood samples. The strong affinity of lipids to charcoal makes carbonized wood ideal for retaining them, but also makes their extraction extremely challenging and thus an ideal benchmark for solvent extraction characterization. Several solvents (benzene, chloroform, hexane, methanol and water are used to determine the quantitative extraction efficiency of tripalmitin. While benzene and chloroform perform best for some wood types, neither solvent is better for all carbonized wood. Correlations between the chemical properties of the solvents and the effectiveness of the extraction provide guidance for solvents. Findings indicate solvent characteristics including dipole moment, dielectric constant, hydrogen bonding, and molecular weight all play an important role in extraction of fat from a charcoal matrix. Results presented should provide guidelines to allow for more effective residue extration and more accurate lipid analysis.

  3. Choice in experiential learning: True preferences or experimental artifacts? (United States)

    Ashby, Nathaniel J S; Konstantinidis, Emmanouil; Yechiam, Eldad


    The rate of selecting different options in the decisions-from-feedback paradigm is commonly used to measure preferences resulting from experiential learning. While convergence to a single option increases with experience, some variance in choice remains even when options are static and offer fixed rewards. Employing a decisions-from-feedback paradigm followed by a policy-setting task, we examined whether the observed variance in choice is driven by factors related to the paradigm itself: Continued exploration (e.g., believing options are non-stationary) or exploitation of perceived outcome patterns (i.e., a belief that sequential choices are not independent). Across two studies, participants showed variance in their choices, which was related (i.e., proportional) to the policies they set. In addition, in Study 2, participants' reported under-confidence was associated with the amount of choice variance in later choices and policies. These results suggest that variance in choice is better explained by participants lacking confidence in knowing which option is better, rather than methodological artifacts (i.e., exploration or failures to recognize outcome independence). As such, the current studies provide evidence for the decisions-from-feedback paradigm's validity as a behavioral research method for assessing learned preferences. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. A level set method for cupping artifact correction in cone-beam CT

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Shipeng; Li, Haibo; Ge, Qi [College of Telecommunications and Information Engineering, Nanjing University of Posts and Telecommunications, Nanjing, Jiangsu 210003 (China); Li, Chunming, E-mail: [School of Electronic Engineering, University of Electronic Science and Technology of China (UESTC), Chengdu, Sichuan 611731 (China)


    Purpose: To reduce cupping artifacts and improve the contrast-to-noise ratio in cone-beam computed tomography (CBCT). Methods: A level set method is proposed to reduce cupping artifacts in the reconstructed image of CBCT. The authors derive a local intensity clustering property of the CBCT image and define a local clustering criterion function of the image intensities in a neighborhood of each point. This criterion function defines an energy in terms of the level set functions, which represent a segmentation result and the cupping artifacts. The cupping artifacts are estimated as a result of minimizing this energy. Results: The cupping artifacts in CBCT are reduced by an average of 90%. The results indicate that the level set-based algorithm is practical and effective for reducing the cupping artifacts and preserving the quality of the reconstructed image. Conclusions: The proposed method focuses on the reconstructed image without requiring any additional physical equipment, is easily implemented, and provides cupping correction through a single-scan acquisition. The experimental results demonstrate that the proposed method successfully reduces the cupping artifacts.

  5. A semi-simulated EEG/EOG dataset for the comparison of EOG artifact rejection techniques. (United States)

    Klados, Manousos A; Bamidis, Panagiotis D


    Artifact rejection techniques are used to recover the brain signals underlying artifactual electroencephalographic (EEG) segments. Although over the last few years many different artifact rejection techniques have been proposed ([1],[2],[3]), none has been established as a gold standard so far, because assessing their performance is difficult and subjective ([4],[5], [6]). This limitation is mainly based on the fact that the underlying artifact-free brain signal is unknown, so there is no objective way to measure how close the retrieved signal is to the real one. This article solves the aforementioned problem by presenting a semi-simulated EEG dataset, where artifact-free EEG signals are manually contaminated with ocular artifacts, using a realistic head model. The significant part of this dataset is that it contains the pre-contamination EEG signals, so the brain signals underlying the EOG artifacts are known and thus the performance of every artifact rejection technique can be objectively assessed.

  6. [Comparison of magnetic resonance imaging artifacts of five common dental materials]. (United States)

    Xu, Yisheng; Yu, Risheng


    To compare five materials commonly used in dentistry, including three types of metals and two types of ceramics, by using different sequences of three magnetic resonance imaging (MRI) field strengths (0.35, 1.5, and 3.0 T). Three types of metals and two types of ceramics that were fabricated into the same size and thickness as an incisor crown were placed in a plastic tank filled with saline. The crowns were scanned using an magnetic resonance (MR) machine at 0.35, 1.5, and 3.0 T field strengths. The TlWI and T2WI images were obtained. The differences of various materials in different artifacts of field MR scans were determined. The zirconia crown presented no significant artifacts when scanned under the three types of MRI field strengths. The artifacts of casting ceramic were minimal. All dental precious metal alloys, nickel-chromium alloy dental porcelain, and cobalt-chromium ceramic alloy showed varying degrees of artifacts under the three MRI field strengths. Zirconia and casting ceramics present almost no or faint artifacts. By contrast, precious metal alloys, nickel-chromium alloy dental porcelain and cobalt-chromium ceramic alloy display MRI artifacts. The artifact area increase with increasing magnetic field.

  7. Methods for artifact detection and removal from scalp EEG: A review. (United States)

    Islam, Md Kafiul; Rastegarnia, Amir; Yang, Zhi


    Electroencephalography (EEG) is the most popular brain activity recording technique used in wide range of applications. One of the commonly faced problems in EEG recordings is the presence of artifacts that come from sources other than brain and contaminate the acquired signals significantly. Therefore, much research over the past 15 years has focused on identifying ways for handling such artifacts in the preprocessing stage. However, this is still an active area of research as no single existing artifact detection/removal method is complete or universal. This article presents an extensive review of the existing state-of-the-art artifact detection and removal methods from scalp EEG for all potential EEG-based applications and analyses the pros and cons of each method. First, a general overview of the different artifact types that are found in scalp EEG and their effect on particular applications are presented. In addition, the methods are compared based on their ability to remove certain types of artifacts and their suitability in relevant applications (only functional comparison is provided not performance evaluation of methods). Finally, the future direction and expected challenges of current research is discussed. Therefore, this review is expected to be helpful for interested researchers who will develop and/or apply artifact handling algorithm/technique in future for their applications as well as for those willing to improve the existing algorithms or propose a new solution in this particular area of research. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  8. Quantitative assessment of an MR technique for reducing metal artifact: application to spin-echo imaging in a phantom

    International Nuclear Information System (INIS)

    Lee, M.J.; Janzen, D.L.; Munk, P.L.; McGowen, A.; MacKay, A.; Xiang, Q.S.


    Objective. To quantify image artifact reduction using a new technique (MARS - metal artifact reduction sequence) in vitro.Design. Coronal T1-weighted MR images were obtained through two metal phantoms (titanium/chromium-cobalt and stainless steel femoral prostheses) immersed in water. Comparison of artifact volume was made with images obtained using conventional and modified (MARS) T1-weighted sequences. Signal intensity values outside a range of ±40% the average signal intensity for water were considered artifact and segmented into low or high signal artifact categories. Considering the arbitrary selection of this threshold value, volumetric calculations of artifact were also evaluated at ±50%, 60%, 70%, and 80% the mean signal for water.Results. Conventional T1-weighted images produced 87% more low signal artifact and 212% more high signal artifact compared with the MARS modified T1-weighted images of the stainless steel prosthesis. Conventional T1-weighted images of the titanium prosthesis produced 84% more low signal artifact and 211% more high signal artifact than the MARS modified sequence. The level of artifact reduction was essentially uniform for the various threshold levels tested and was greatest at ±20% the global signal intensity average for water.Conclusion. The MARS technique reduces the volume of image signal artifact produced by stainless steel and titanium/chromium-cobalt femoral prostheses on T1-weighted spin-echo images in a tissue phantom model. (orig.)

  9. Quantification of MRI visibility and artifacts at 3T of liquid fiducial marker in a pancreas tissue-mimicking phantom

    DEFF Research Database (Denmark)

    Schneider, Sergej; Jølck, Rasmus Irming; Troost, Esther Gera Cornelia


    marker with volumes of 25-100 mu L showing no correlation with the magnitude of artifact. The solid markers showed a strong nonlinear correlation between magnitude of visibility and artifact, whereas the solid marker consisting of a gold-iron alloy induced the strongest artifacts.Conclusion: The liquid...

  10. Spontaneous dislocation of lens bag with acrylic lens after uneventful cataract surgery ? unusual complication of cataract surgery


    Shah, Mehul A.; Shah, Shreya M.; Mehta, Ruchir; Shah, Prerna


    Introduction: Spontaneous dislocation of intraocular lens with bag is rare.Methods: We report a case of a 56-year-old male who presented with spontaneous anterior dislocation of an in-the-bag intraocular lens 3 years after manual small incision cataract surgery. He had undergone manual small incision cataract surgery with foldable acrylic intraocular lens implantation, and 18 months after cataract surgery ND: YAG capsulotomy with uneventful post capsulotomy follow-up. 17 months after capsul...

  11. Projection-based metal-artifact reduction for industrial 3D X-ray computed tomography. (United States)

    Amirkhanov, Artem; Heinzl, Christoph; Reiter, Michael; Kastner, Johann; Gröller, M Eduard


    Multi-material components, which contain metal parts surrounded by plastic materials, are highly interesting for inspection using industrial 3D X-ray computed tomography (3DXCT). Examples of this application scenario are connectors or housings with metal inlays in the electronic or automotive industry. A major problem of this type of components is the presence of metal, which causes streaking artifacts and distorts the surrounding media in the reconstructed volume. Streaking artifacts and dark-band artifacts around metal components significantly influence the material characterization (especially for the plastic components). In specific cases these artifacts even prevent a further analysis. Due to the nature and the different characteristics of artifacts, the development of an efficient artifact-reduction technique in reconstruction-space is rather complicated. In this paper we present a projection-space pipeline for metal-artifacts reduction. The proposed technique first segments the metal in the spatial domain of the reconstructed volume in order to separate it from the other materials. Then metal parts are forward-projected on the set of projections in a way that metal-projection regions are treated as voids. Subsequently the voids, which are left by the removed metal, are interpolated in the 2D projections. Finally, the metal is inserted back into the reconstructed 3D volume during the fusion stage. We present a visual analysis tool, allowing for interactive parameter estimation of the metal segmentation. The results of the proposed artifact-reduction technique are demonstrated on a test part as well as on real world components. For these specimens we achieve a significant reduction of metal artifacts, allowing an enhanced material characterization. © 2010 IEEE

  12. Enhanced detection of artifacts in EEG data using higher-order statistics and independent component analysis (United States)

    Delorme, Arnaud; Sejnowski, Terrence; Makeig, Scott


    Detecting artifacts produced in EEG data by muscle activity, eye blinks and electrical noise is a common and important problem in EEG research. It is now widely accepted that independent component analysis (ICA) may be a useful tool for isolating artifacts and/or cortical processes from electroencephalographic (EEG) data. We present results of simulations demonstrating that ICA decomposition, here tested using three popular ICA algorithms Infomax, SOBI, and FastICA, can allow more sensitive automated detection of small non-brain artifacts than applying the same detection methods directly to the scalp channel data. We tested the upper bound performance of five methods for detecting various types of artifacts by separately optimizing and then applying them to artifact-free EEG data into which we had added simulated artifacts of several types, ranging in size from thirty times smaller (−50 dB) to the size of the EEG data themselves (0 dB). Of the methods tested, those involving spectral thresholding were most sensitive. Except for muscle artifact detection where we found no gain of using ICA, all methods proved more sensitive when applied to the ICA-decomposed data than applied to the raw scalp data: the mean performance for ICA was higher and situated at about two standard deviations away from the performance distribution obtained on raw data. We note that ICA decomposition also allows simple subtraction of artifacts accounted for by single independent components, and/or separate and direct examination of the decomposed non-artifact processes themselves. PMID:17188898

  13. Spurious structures created by interpolation-based CT metal artifact reduction (United States)

    Müller, J.; Buzug, T. M.


    Under normal circumstances the quality of images reconstructed with the classic FBP CT reconstruction algorithm is adequate for medical diagnosis. However, in some special cases the assumptions made by this method are not applicable because of non-linearities in the underlying physical imaging processes. Especially in the presence of metal implants in the field of view, effects like beam hardening, scatter and photon starvation result in serious streaking and banding artifacts around and between these objects. In order to reduce the artifacts, several different types of correction methods were introduced during the last two decades. In one of the most often used approaches, an interpolation scheme is used to replace all corrupted beam data in the shadow of the metal with artificially generated values. Although this leads to a reduction of the most severe artifacts, typically the results are far from being perfect. Instead of removing all artifacts, in most cases new streak artifacts are introduced. In the present work it is shown that the origin of these new artifacts is related to the loss of edge information of the objects by using surrogate data. The application of a more sophisticated artifact reduction method based on a segmentation of a preliminary reconstructed image decreases the number of newly introduced artifacts to a large degree. This is possible, because edge information between air and tissue recovered from the preliminary reconstruction can be included into the correction scheme. It is concluded that a restoration scheme without additionally information is not sufficient for a successful metal artifact reduction method.

  14. SU-F-I-08: CT Image Ring Artifact Reduction Based On Prior Image

    International Nuclear Information System (INIS)

    Yuan, C; Qi, H; Chen, Z; Wu, S; Xu, Y; Zhou, L


    Purpose: In computed tomography (CT) system, CT images with ring artifacts will be reconstructed when some adjacent bins of detector don’t work. The ring artifacts severely degrade CT image quality. We present a useful CT ring artifacts reduction based on projection data correction, aiming at estimating the missing data of projection data accurately, thus removing the ring artifacts of CT images. Methods: The method consists of ten steps: 1) Identification of abnormal pixel line in projection sinogram; 2) Linear interpolation within the pixel line of projection sinogram; 3) FBP reconstruction using interpolated projection data; 4) Filtering FBP image using mean filter; 5) Forwarding projection of filtered FBP image; 6) Subtraction forwarded projection from original projection; 7) Linear interpolation of abnormal pixel line area in the subtraction projection; 8) Adding the interpolated subtraction projection on the forwarded projection; 9) FBP reconstruction using corrected projection data; 10) Return to step 4 until the pre-set iteration number is reached. The method is validated on simulated and real data to restore missing projection data and reconstruct ring artifact-free CT images. Results: We have studied impact of amount of dead bins of CT detector on the accuracy of missing data estimation in projection sinogram. For the simulated case with a resolution of 256 by 256 Shepp-Logan phantom, three iterations are sufficient to restore projection data and reconstruct ring artifact-free images when the dead bins rating is under 30%. The dead-bin-induced artifacts are substantially reduced. More iteration number is needed to reconstruct satisfactory images while the rating of dead bins increases. Similar results were found for a real head phantom case. Conclusion: A practical CT image ring artifact correction scheme based on projection data is developed. This method can produce ring artifact-free CT images feasibly and effectively.

  15. Image-based metal artifact reduction in x-ray computed tomography utilizing local anatomical similarity (United States)

    Dong, Xue; Yang, Xiaofeng; Rosenfield, Jonathan; Elder, Eric; Dhabaan, Anees


    X-ray computed tomography (CT) is widely used in radiation therapy treatment planning in recent years. However, metal implants such as dental fillings and hip prostheses can cause severe bright and dark streaking artifacts in reconstructed CT images. These artifacts decrease image contrast and degrade HU accuracy, leading to inaccuracies in target delineation and dose calculation. In this work, a metal artifact reduction method is proposed based on the intrinsic anatomical similarity between neighboring CT slices. Neighboring CT slices from the same patient exhibit similar anatomical features. Exploiting this anatomical similarity, a gamma map is calculated as a weighted summation of relative HU error and distance error for each pixel in an artifact-corrupted CT image relative to a neighboring, artifactfree image. The minimum value in the gamma map for each pixel is used to identify an appropriate pixel from the artifact-free CT slice to replace the corresponding artifact-corrupted pixel. With the proposed method, the mean CT HU error was reduced from 360 HU and 460 HU to 24 HU and 34 HU on head and pelvis CT images, respectively. Dose calculation accuracy also improved, as the dose difference was reduced from greater than 20% to less than 4%. Using 3%/3mm criteria, the gamma analysis failure rate was reduced from 23.25% to 0.02%. An image-based metal artifact reduction method is proposed that replaces corrupted image pixels with pixels from neighboring CT slices free of metal artifacts. This method is shown to be capable of suppressing streaking artifacts, thereby improving HU and dose calculation accuracy.

  16. Characterization of Aortic Valve Closure Artifact During Outflow Tract Mapping: Correlation With Hemodynamics and Mechanical Valves. (United States)

    Romero, Jorge; Ajijola, Olujimi; Shivkumar, Kalyanam; Tung, Roderick


    Premature ventricular contractions originating in the left ventricle outflow tract represent a significant subgroup of patients referred for catheter ablation. Mechanical artifacts from aortic valve leaflet motion may be observed during mapping, although the incidence and characteristics have not been reported. Twenty-eight consecutive patients with left ventricle outflow tract premature ventricular contraction were included. Electric signals recorded on the ablation catheter not coincident with atrial or ventricular depolarization were analyzed on the recording system. Correlation with invasive hemodynamic aortic pressure tracings was performed. Additionally, 4 patients with mechanical aortic valves, who underwent scar-related ventricular tachycardia ablation, were analyzed to correlate the timing of the observed artifacts with native aortic valves. Aortic valve artifact was observed while mapping within the coronary cusps in 11 patients (39%; 73% men; age, 41±25 years; left ventricular ejection fraction 49±16%) with high incidence from the left coronary cusp. This artifact was consistently observed with timing coincident with the terminal portion of the T wave. The average interval between the end of the T wave and the aortic valve artifact was 19±37 ms. The duration of the aortic valve artifact was 39±8 ms with amplitude of 0.12±0.07 mV (range, 0.06-0.36 mV). In patients referred for left ventricle outflow tract premature ventricular contraction ablation, an aortic valve closure artifact is observed in up to one third of cases during mapping within the aortic cusps. The timing of this artifact correlates with invasive hemodynamics and mechanical aortic valve artifacts. Recognition of this physiological phenomenon is useful when assigning near-field activation. © 2017 American Heart Association, Inc.

  17. LENS - the Low-Energy Neutrino Spectrometer

    International Nuclear Information System (INIS)

    Hahn, Richard L.


    Despite the recent successes of SNO and KamLAND, the only detectors sensitive to <1 MeV-neutrinos have been the radiochemical chlorine and gallium solar neutrino experiments. LENS is being developed to measure in real time the charge-current fluxes and energy spectra of the lowest energy solar neutrinos, from the pp and 7Be branches (91% and 7% of solar neutrinos). The detector medium will be a metal-loaded liquid scintillator (M-LS), with indium as the metal, which serves as the target for neutrino capture in the LS. 115In has 95.71% natural abundance and a 114.2-keV neutrino-capture Q-value. Neutrino capture in 115In produces a β particle and preferentially feeds an excited state of 115Sn that de-excites by delayed emission of two γ rays. This triple-coincidence 'tag' in time and space in principle is a very powerful tool to discriminate neutrino-capture events from backgrounds. The International LENS R and D Collaboration is working to develop an In-LS neutrino detector, with special properties, such as high indium content, high light yield, high optical transparency, long-term chemical stability, and good signal-to-background ratio. Success in preparing the In-LS has been achieved via the synthesis of In-carboxylates that are soluble in pseudocumene LS (note that these methods may also be applicable to the preparation of Gd-LS for reactor antineutrino experiments). Testing of some prototype LENS In-LS detector modules has begun recently at the Gran Sasso Laboratory

  18. [Corneal protection in contact lens users]. (United States)

    Egorova, G B; Mitichkina, T S; Shamsudinova, A R


    To evaluate the efficacy of corneoprotective agents (Corneregel and Solcoseryl) in contact lens users. A total of 66 long-term contact lens wearers with dry eye symptoms and varying degrees of corneal epitheliopathy were monitored. All patients used artificial tears, which, however, were not effective enough to suppress manifestations of corneal epitheliopathy and to release the associated discomfort. The therapy was supplemented with Corneregel. The following examination methods were applied: biomicroscopy with fluorescent staining, Norn test, Schirmer's test, advanced tearscopy with digital image analysis of the precorneal tear film lipid layer, corneal confocal microscopy. In all cases the assessment was performed prior to starting Corneregel and repeated in 7 days, 14 days and 1 month. Complete corneal re-epithelization and restoration of the most superficial layer of the epithelium were achieved within 7-14 days. In case of severe initial epitheliopathy the effect of Corneregel was not sufficient and epithelium defects remained. These patients additionally received Solcoseryl Eye Gel. After the treatment course the condition of corneal epithelium ameliorated and contact lens wearing comfort increased. A longer precorneal tear film break-up time indicated an increase of tear film stability. The total tear production did not change significantly. The moistening effect of Corneregel and low-viscosity artificial tears together with intensive regeneration of corneal epithelium enables structural recovery of the epithelial membrane and considerable improvement of the anterior corneal stroma. At the first stage of corneoprotective treatment it is appropriate to use preservative-free artificial tears of low and high viscosity. If the effect of tear substitutive therapy is unsatisfactory it is recommended to prescribe Corneregel and Solcoseryl. The regimen is to be adjusted individually.

  19. Lentil (Lens culinaris) Lipid Transfer Protein Len c 3: A Novel Legume Allergen

    NARCIS (Netherlands)

    Akkerdaas, J.; Finkina, E. I.; Balandin, S. V.; Santos Magadán, S.; Knulst, A.; Fernandez-Rivas, M.; Asero, R.; van Ree, R.; Ovchinnikova, T. V.


    Background: Lentils are increasingly consumed in many parts of the world. Two allergens, Len c 1 and 2, have been reported previously. Recently, peanut and green bean lipid transfer proteins (LTPs) have been identified as the first two members of an important group of allergens that might be

  20. Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function

    Czech Academy of Sciences Publication Activity Database

    Krešlová, Jana; Machoň, Ondřej; Růžičková, Jana; Láchová, Jitka; Wawrousek, E.F.; Kemler, R.; Krauss, S.; Piatigorsky, J.; Kozmik, Zbyněk


    Roč. 45, č. 4 (2007), s. 157-168 ISSN 1526-954X R&D Projects: GA ČR GA204/04/1358 Institutional research plan: CEZ:AV0Z50520514 Keywords : Wnt * beta-catenin * gene * lens Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.516, year: 2007

  1. Magnetic system of the Tevatron electron lens

    International Nuclear Information System (INIS)

    Bogdanov, I.; Kozub, S.; Pleskach, V.; Sytnik, V.; Tkachenko, L.; Zintchenko, S.; Zubko, V.; Kuznetsov, G.; Sery, A.; Shiltsev, V.


    The Tevatron Electron Lens (TEL) system consisting of seven SC and four conventional magnets has been developed and fabricated in IHEP for increase of luminosity in Tevatron. The SC cable tension and preload of SC coils are calculated. The chosen cable design and cooling of the SC magnets ensure sufficient temperature margin for operating of SC magnets and their safety during quench. The system of conventional and SC solenoids create necessary trajectory of magnetic field lines for the TEL electron beam motion. SC dipoles and warm correctors permit to carry out correction of the electron beam motion [ru

  2. Septic lens implantation syndrome in a cat. (United States)

    Dalesandro, Nicole; Stiles, Jean; Miller, Margaret


    A 13-year-old female spayed domestic shorthair cat was presented initially for a change in the appearance of the left eye. On initial examination, a small penetrating wound was suspected as the cause for a corneal scar, an anterior cortical incipient cataract and mild iritis. The cat was not re-presented until 1 year later at which time ocular pain was marked. Severe anterior uveitis and glaucoma were diagnosed and the eye enucleated. Histopathology documented intralenticular coccoid bacteria and septic lens implantation syndrome. © 2011 American College of Veterinary Ophthalmologists.

  3. [Contact lens-associated Paecilomyces lilacinus keratitis]. (United States)

    Mihailovic, N; Alnawaiseh, M; Zumhagen, L; Eter, N


    We present the case of a 23-year-old otherwise healthy female patient with contact lens-associated Paecilomyces lilacinus keratitis. The clinical findings stabilized after initial local antimycotic and antibacterial treatment; however, in the further course of local therapy an extensive relapse occurred which required treatment by perforating keratoplasty à chaud due to a penetrating corneal ulcer. The patient responded well to subsequent treatment with systemic and local antimycotic medication. After a few months HLA-matched keratoplasty was performed. During the follow-up time of 14 months there were no signs of recurrence of the infection.

  4. Scleral lens for keratoconus: technology update


    Rathi, Varsha; Taneja,Mukesh; Mandathara,Preeji; Sangwan,Virender; Dumpati,Srikanth


    Varsha M Rathi,1 Preeji S Mandathara,2 Mukesh Taneja,1 Srikanth Dumpati,1 Virender S Sangwan1 1L V Prasad Eye Institute, Hyderabad, India; 2School of Optometry and Vision Science, University of New South Wales, Kensington, NSW, Australia Abstract: Scleral lenses are large diameter lenses which rest over the sclera, unlike the conventional contact lenses which rest on the cornea. These lenses are fitted to not touch the cornea and there is a space created between the cornea and the lens. Th...

  5. Scientific performance assessments through a gender lens

    DEFF Research Database (Denmark)

    Nielsen, Mathias Wullum


    The focus on excellence and quality assurance in the academy has spawned a signifi cant increase in the use of bibliometric measures in performance assessments of individual researchers. This article investigates the organizational consequences of this development through a gender lens. Based....... They adhere to the prevailing ethos of the academic meritocracy by standardizing the criteria for organizational advancement and ensuring transparency and accountability in the selection process. While bibliometric tools in this sense may lead to the recruitment of scientists with a strong CV and track record...

  6. Polarization response of RHIC electron lens lattices

    Directory of Open Access Journals (Sweden)

    V. H. Ranjbar


    Full Text Available Depolarization response for a system of two orthogonal snakes at irrational tunes is studied in depth using lattice independent spin integration. In particular we consider the effect of overlapping spin resonances in this system, to understand the impact of phase, tune, relative location and threshold strengths of the spin resonances. These results are benchmarked and compared to two dimensional direct tracking results for the RHIC e-lens lattice and the standard lattice. Finally we consider the effect of longitudinal motion via chromatic scans using direct six dimensional lattice tracking.

  7. A dialectical take on artifact ecologies and the physical - digital divide

    DEFF Research Database (Denmark)

    Bødker, Susanne; Klokmose, Clemens Nylandsted

    In this position paper, we will present and discuss our understanding of artifact ecologies as we have developed it, rooted in activity theoretical HCI and dialectical thinking . Our basis is in the Human-Artifact Model, as well as well as cases where we have worked with artifact ecologies in ana...... in analysis and design of computer mediated activity. The paper concludes with a positioning of our perspective vis-a-vis the notions of natural and blended interaction and the physical-digital divide...

  8. I Am My Identity Kit : using Artifact Data in Research on Identity


    LeCompte, Margaret D.


    Este texto se presentó como comunicación al II Congreso Internacional de Etnografía y Educación: Migraciones y Ciudadanías. Universidad Autónoma de Barcelona, Barcelona, 5-8 Septiembre 2008. This presentation addresses how to collect and analyze artifacts in ethnographic and qualitative research, and the value of using artifacts in research which seeks to describe and interpret the identities that research participants construct. We believe that artifacts can be very useful in such researc...

  9. Ancient Artifacts vs. Digital Artifacts: New Tools for Unmasking the Sale of Illicit Antiquities on the Dark Web

    Directory of Open Access Journals (Sweden)

    Katie A. Paul


    Full Text Available Since the rise of the Islamic State of Iraq and Syria (ISIS, also known as Daesh and ISIL in 2014, antiquities have been a widely publicized source of funding for what has become one of the most technologically savvy terrorist organizations of the modern era. The globalization of technology and rise of popularity in cryptocurrencies has changed the face of black-market trade and the actors that carry out these crimes. While art and antiquities have long served as a market with susceptibilities to laundering, the emergence of Dark Web markets, identification-masking software, and untraceable cryptocurrencies such as Bitcoin have opened new doors to potential vulnerabilities. The anonymity that is offered by these technologies acts as a roadblock for authorities, while attracting the likes of terrorists and transnational criminals. Investigative research using cyber security platforms to identify digital artifacts connected to potential traffickers provides the opportunity to unmask the seemingly untraceable actors behind these activities. The evidence of illicit antiquities trafficking on the Dark Web displayed in this article can generate a new discussion on how and where to study black-market antiquities to gain needed insight into combating the illicit trade online and the transnational criminal groups it may finance.

  10. Candidate gravitational microlensing events for future direct lens imaging

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, C. B.; Gould, A.; Gaudi, B. S. [Department of Astronomy, The Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Park, H.; Han, C. [Department of Physics, Institute for Astrophysics, Chungbuk National University, Cheongju 371-763 (Korea, Republic of); Sumi, T.; Koshimoto, N. [Department of Earth and Space Science, Osaka University, Osaka 560-0043 (Japan); Udalski, A. [Warsaw University Observatory, Al. Ujazdowskie 4, 00-478 Warszawa (Poland); Tsapras, Y. [Las Cumbres Observatory Global Telescope Network, 6740 Cortona Drive, Suite 102, Goleta, CA 93117 (United States); Bozza, V. [Department of Physics, University of Salerno, I-84084 Fisciano (Italy); Abe, F.; Fukunaga, D.; Itow, Y.; Masuda, K. [Solar-Terrestrial Environment Laboratory, Nagoya University, Nagoya 464-8601 (Japan); Bennett, D. P. [Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN 46556-5670 (United States); Bond, I. A.; Ling, C. H. [Institute of Information and Mathematical Sciences, Massey University, Private Bag 102-904, North Shore Mail Centre, Auckland 0745 (New Zealand); Botzler, C. S.; Freeman, M. [Department of Physics, University of Auckland, Private Bag 92-019, Auckland 1001 (New Zealand); Fukui, A. [School of Chemical and Physical Sciences, Victoria University, Wellington 6140 (New Zealand); Collaboration: MOA Collaboration; OGLE Collaboration; μFUN Collaboration; RoboNet Collaboration; and others


    The mass of the lenses giving rise to Galactic microlensing events can be constrained by measuring the relative lens-source proper motion and lens flux. The flux of the lens can be separated from that of the source, companions to the source, and unrelated nearby stars with high-resolution images taken when the lens and source are spatially resolved. For typical ground-based adaptive optics (AO) or space-based observations, this requires either inordinately long time baselines or high relative proper motions. We provide a list of microlensing events toward the Galactic bulge with high relative lens-source proper motion that are therefore good candidates for constraining the lens mass with future high-resolution imaging. We investigate all events from 2004 to 2013 that display detectable finite-source effects, a feature that allows us to measure the proper motion. In total, we present 20 events with μ ≳ 8 mas yr{sup –1}. Of these, 14 were culled from previous analyses while 6 are new, including OGLE-2004-BLG-368, MOA-2005-BLG-36, OGLE-2012-BLG-0211, OGLE-2012-BLG-0456, MOA-2012-BLG-532, and MOA-2013-BLG-029. In ≲12 yr from the time of each event the lens and source of each event will be sufficiently separated for ground-based telescopes with AO systems or space telescopes to resolve each component and further characterize the lens system. Furthermore, for the most recent events, comparison of the lens flux estimates from images taken immediately to those estimated from images taken when the lens and source are resolved can be used to empirically check the robustness of the single-epoch method currently being used to estimate lens masses for many events.

  11. International survey of contact lens prescribing for extended wear. (United States)

    Efron, Nathan; Morgan, Philip B; Woods, Craig A


    To determine the extent of extended wear (EW) contact lens prescribing worldwide and to characterize the associated demographics and fitting patterns. Up to 1000 survey forms were sent to contact lens fitters in up to 39 countries between January and March every year for five consecutive years (2006-2010). Practitioners were asked to record data relating to the first 10 contact lens fits or refits performed after receiving the survey form. Survey data collected since 1997 was also analyzed to assess EW fitting trends since that time. Details for lens modality were received for 107,094 rigid and soft lens fits of which 88,392 were for soft lens daily wear (DW) and 7470 were for soft lens EW. Overall, EW represents 7.8% of all soft lens fits, ranging from 0.6% in Malaysia to 27% Norway. Compared with DW fittings, EW fittings can be characterized as follows: older age (32.7 ± 13.6 vs. 29.4 ± 12.0 years for DW); males are over-represented; greater proportion of refits; 72% silicone hydrogel; higher proportion of presbyopia and spherical designs; and higher proportion of monthly lens replacement. Of those wearing EW lenses, 80% use multipurpose solutions, whereas 9% do not use any care system. Between 1997 and 1999, the rate of EW prescribing decreased from 5 to 1% of all soft lens fits; it increased to a peak of 12% in 2006, and settled back to 8% by 2010. EW prescribing has failed to break through the "glass ceiling" of 15% and is unlikely to become a mainstream lens wearing modality until the already low risks of ocular complications can be reduced to be equivalent to that for DW.

  12. SU-F-J-74: High Z Geometric Integrity and Beam Hardening Artifact Assessment Using a Retrospective Metal Artifact Reduction (MAR) Reconstruction Algorithm

    International Nuclear Information System (INIS)

    Woods, K; DiCostanzo, D; Gupta, N


    Purpose: To test the efficacy of a retrospective metal artifact reduction (MAR) reconstruction algorithm for a commercial computed tomography (CT) scanner for radiation therapy purposes. Methods: High Z geometric integrity and artifact reduction analysis was performed with three phantoms using General Electric’s (GE) Discovery CT. The three phantoms included: a Computerized Imaging Reference Systems (CIRS) electron density phantom (Model 062) with a 6.5 mm diameter titanium rod insert, a custom spine phantom using Synthes Spine hardware submerged in water, and a dental phantom with various high Z fillings submerged in water. Each phantom was reconstructed using MAR and compared against the original scan. Furthermore, each scenario was tested using standard and extended Hounsfield Unit (HU) ranges. High Z geometric integrity was performed using the CIRS phantom, while the artifact reduction was performed using all three phantoms. Results: Geometric integrity of the 6.5 mm diameter rod was slightly overestimated for non-MAR scans for both standard and extended HU. With MAR reconstruction, the rod was underestimated for both standard and extended HU. For artifact reduction, the mean and standard deviation was compared in a volume of interest (VOI) in the surrounding material (water and water equivalent material, ∼0HU). Overall, the mean value of the VOI was closer to 0 HU for the MAR reconstruction compared to the non-MAR scan for most phantoms. Additionally, the standard deviations for all phantoms were greatly reduced using MAR reconstruction. Conclusion: GE’s MAR reconstruction algorithm improves image quality with the presence of high Z material with minimal degradation of its geometric integrity. High Z delineation can be carried out with proper contouring techniques. The effects of beam hardening artifacts are greatly reduced with MAR reconstruction. Tissue corrections due to these artifacts can be eliminated for simple high Z geometries and greatly

  13. Color dissociation artifacts in double Maddox rod cyclodeviation testing. (United States)

    Simons, K; Arnoldi, K; Brown, M H


    The double Maddox rod test, based on a red Maddox rod in front of one eye and a clear Maddox rod in front of the other, is used to measure cyclodeviation, typically in patients with superior oblique muscle pareses. Discrepant results between the double Maddox rod test and other torsion measures, and reports of "paradoxic" cyclodeviation in the normal eye of some patients with superior oblique paresis, suggest the two-color format of the double Maddox rod test may produce artifactual torsion measures. Forty patients with superior oblique paresis were tested twice using the double Maddox rod test, reversing the red and white Maddox rods between eyes for the second test, and 18 were tested further with same-color red or clear Maddox rods in front of both eyes. With the standard double Maddox rod test, 33 (83%) of 40 patients localized their cyclodeviation to the eye viewing through the red Maddox rod, irrespective of laterality of the paresis or fixation preference. In all 33 patients, laterality of the perceived torsion changed between eyes when testing was repeated with red and white Maddox rods interchanged between eyes. With same-color Maddox rods before both eyes, 17 (94%) of 18 patients localized extorsion to the paretic eye. There was 7.6:1 ratio of luminance transmission and a 1.6:1 ratio of grating spatial frequency bandpass in the plano meridian between the clear and red Maddox rods, which appear to be responsible for the double Maddox rod test artifact. The traditional double Maddox rod test may produce artifactual cyclodeviation measurements. An alternative version of the test, based on same-color Maddox rods in front of both eyes, is proposed. The relatively high spatial frequency bandpass characteristics of the plano meridian of the Maddox rod (as high as 20/25 Snellen equivalent resolution through the clear Maddox rod) also suggests double Maddox rod testing should be conducted in a dark room to avoid biases from visual environment cues.

  14. Anticoagulant Effect of Sugammadex: Just an In Vitro Artifact. (United States)

    Dirkmann, Daniel; Britten, Martin W; Pauling, Henning; Weidle, Juliane; Volbracht, Lothar; Görlinger, Klaus; Peters, Jürgen


    Sugammadex prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT) suggestive of anticoagulant effects. To pinpoint its presumed anticoagulant site of action, the authors assessed Sugammadex's impact on a panel of coagulation assays. Sugammadex, Rocuronium, Sugammadex and Rocuronium combined, or saline were added to blood samples from healthy volunteers and analyzed using plasmatic (i.e., aPTT, thrombin time, and fibrinogen concentration) (n = 8 each), PT (quick), activities of plasmatic coagulation factors, and whole blood (extrinsically and intrinsically activated thromboelastometry) assays (n = 18 each). Furthermore, dose-dependent effects of Sugammadex were also assessed (n = 18 each) in diluted Russel viper venom time (DRVVT) assays with low (DRVVT1) and high (DRVVT2) phospholipid concentrations and in a highly phospholipid-sensitive aPTT assay. Sugammadex increased PT (+9.1%; P IX, XI, and XII decreased (-7%, P = 0.009; -7.8%, P < 0.0001; -6.9%, P < 0.0001; and -4.3%, P = 0.011, respectively). Sugammadex dose-dependently prolonged both DRVVT1 and the highly phospholipid-sensitive aPTT assays, but additional phospholipids in the DRVVT2 assay almost abolished these prolongations. Thrombin time, a thromboelastometric thrombin generation assay, clot firmness, clot lysis, fibrinogen concentration, and activities of other coagulation factors were unaltered. Rocuronium, Sugammadex and Rocuronium combined, and saline exerted no effects. Sugammadex significantly affects various coagulation assays, but this is explainable by an apparent phospholipid-binding effect, suggesting that Sugammadex`s anticoagulant effects are likely an in vitro artifact.

  15. Low-dose CT of the paranasal sinuses with eye lens protection: effect on image quality and radiation dose

    Energy Technology Data Exchange (ETDEWEB)

    Hein, Eike; Rogalla, Patrik; Klingebiel, Randolph; Hamm, Bernd [Department of Diagnostic and Interventional Radiology, Charite Hospital, Humboldt-Universitaet zu Berlin (Germany)


    The purpose of the study was to assess the effect of lens protection on image quality and radiation dose to the eye lenses in CT of the paranasal sinuses. In 127 patients referred to rule out sinusitis, an axial spiral CT with a lens protection placed on the patients eyes was obtained (1.5/2/1, 50 mAs, 120 kV). Coronal views were reconstructed at 5-mm interval. To quantify a subjective impression of image quality, three regions of interest within the eyeball were plotted along a line perpendicular to the protection at 2, 5, and 9 mm beneath skin level on the axial images. Additionally, dose reduction of a bismuth-containing latex shield was measured using a film-dosimetry technique. The average eyeball density was 17.97 HU (SD 3.7 HU). The relative increase in CT density was 180.6 (17.7), 103.3 (11.7), and 53.6 HU (9.2), respectively. There was no diagnostic information loss on axial and coronal views observed. Artifacts were practically invisible on images viewed in a bone window/level setting. The use of the shield reduced skin radiation from 7.5 to 4.5 mGy. The utilization of a radioprotection to the eye lenses in paranasal CT is a suitable and effective means of reducing skin radiation by 40%. (orig.)

  16. Dose limits to the eye lens

    Energy Technology Data Exchange (ETDEWEB)

    Sion, N.


    Protecting the human body from the effects of ionizing radiation is essential to forestall stochastic effects and require placing limits on the effective dose. Dose limits on specific organs are also necessary to reduce the deterministic effects and tissue reactions. The standard for radiation protection was ISO 15382 (2002) which mainly dealt with beta radiation for nuclear power plant workers. Clearly an update is required to allow for new technology and the proliferative use of radiation in medical practices. There is a need for more explicit radiation monitoring to operators and staff. ICRP118 (International Commission on Radiological Protection), Ref. 1, evolved their recommendations to include eye lens doses as a follow on to their publication 103 and to focus on radiation exposures. It provides updated estimates of 'practical' threshold doses for tissue injury at the level of 1% incidence. This paper discusses the current status and the recommendation for a drastic reduction of the dose limit to the eye lens. (author)

  17. Scleral lens for keratoconus: technology update

    Directory of Open Access Journals (Sweden)

    Rathi VM


    Full Text Available Varsha M Rathi,1 Preeji S Mandathara,2 Mukesh Taneja,1 Srikanth Dumpati,1 Virender S Sangwan1 1L V Prasad Eye Institute, Hyderabad, India; 2School of Optometry and Vision Science, University of New South Wales, Kensington, NSW, Australia Abstract: Scleral lenses are large diameter lenses which rest over the sclera, unlike the conventional contact lenses which rest on the cornea. These lenses are fitted to not touch the cornea and there is a space created between the cornea and the lens. These lenses are inserted in the eyes after filling with sterile isotonic fluid. Generally, scleral contact lenses are used for high irregular astigmatism as seen in various corneal ectatic diseases such as keratoconus, pellucid marginal degeneration, or/and as liquid bandage in ocular surface disorders. In this article, we review the new developments, that have taken place over the years, in the field of scleral contact lenses as regard to new designs, materials, manufacturing technologies, and fitting strategies particularly for keratoconus. Keywords: keratoconus, scleral lens, technology update, PROSE

  18. Curiosity's Mars Hand Lens Imager (MAHLI) Investigation (United States)

    Edgett, Kenneth S.; Yingst, R. Aileen; Ravine, Michael A.; Caplinger, Michael A.; Maki, Justin N.; Ghaemi, F. Tony; Schaffner, Jacob A.; Bell, James F.; Edwards, Laurence J.; Herkenhoff, Kenneth E.; Heydari, Ezat; Kah, Linda C.; Lemmon, Mark T.; Minitti, Michelle E.; Olson, Timothy S.; Parker, Timothy J.; Rowland, Scott K.; Schieber, Juergen; Sullivan, Robert J.; Sumner, Dawn Y.; Thomas, Peter C.; Jensen, Elsa H.; Simmonds, John J.; Sengstacken, Aaron J.; Wilson, Reg G.; Goetz, Walter


    The Mars Science Laboratory (MSL) Mars Hand Lens Imager (MAHLI) investigation will use a 2-megapixel color camera with a focusable macro lens aboard the rover, Curiosity, to investigate the stratigraphy and grain-scale texture, structure, mineralogy, and morphology of geologic materials in northwestern Gale crater. Of particular interest is the stratigraphic record of a ?5 km thick layered rock sequence exposed on the slopes of Aeolis Mons (also known as Mount Sharp). The instrument consists of three parts, a camera head mounted on the turret at the end of a robotic arm, an electronics and data storage assembly located inside the rover body, and a calibration target mounted on the robotic arm shoulder azimuth actuator housing. MAHLI can acquire in-focus images at working distances from ?2.1 cm to infinity. At the minimum working distance, image pixel scale is ?14 μm per pixel and very coarse silt grains can be resolved. At the working distance of the Mars Exploration Rover Microscopic Imager cameras aboard Spirit and Opportunity, MAHLI?s resolution is comparable at ?30 μm per pixel. Onboard capabilities include autofocus, auto-exposure, sub-framing, video imaging, Bayer pattern color interpolation, lossy and lossless compression, focus merging of up to 8 focus stack images, white light and longwave ultraviolet (365 nm) illumination of nearby subjects, and 8 gigabytes of non-volatile memory data storage.

  19. An adjustable electron achromat for cathode lens microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Tromp, R.M., E-mail: [IBM T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598 (United States); Leiden Institute of Physics, Kamerlingh Onnes Laboratory, Niels Bohrweg 2, 2333 CA Leiden (Netherlands)


    Chromatic aberration correction in light optics began with the invention of a two-color-corrected achromatic crown/flint lens doublet by Chester Moore Hall in 1730. Such color correction is necessary because any single glass shows dispersion (i.e. its index of refraction changes with wavelength), which can be counteracted by combining different glasses with different dispersions. In cathode lens microscopes (such as Photo Electron Emission Microscopy – PEEM) we encounter a similar situation, where the chromatic aberration coefficient of the cathode lens shows strong dispersion, i.e. depends (non-linearly) on the energy with which the electrons leave the sample. Here I show how a cathode lens in combination with an electron mirror can be configured as an adjustable electron achromat. The lens/mirror combination can be corrected at two electron energies by balancing the settings of the electron mirror against the settings of the cathode lens. The achromat can be adjusted to deliver optimum performance, depending on the requirements of a specific experiment. Going beyond the achromat, an apochromat would improve resolution and transmission by a very significant margin. I discuss the requirements and outlook for such a system, which for now remains a wish waiting for fulfilment. - Highlights: • The properties of cathode objective lens plus electron mirror are discussed. • In analogy with light-optical achromats, cathode lens plus mirror can be configured as an electron achromat. • Unlike light optics, the electron achromat can be adjusted to best fulfill experimental requirements.

  20. Near UV radiation effect on the lens and retina

    International Nuclear Information System (INIS)

    Zigman, S.


    The discussion presented in this paper indicates that the retina of a diurnal animal with a natural UV-absorbing lens (ie: the gray squirrel) is susceptible to near-UV damage from environmental sources only after the lens has been removed. This suggests that it is very important to protect against near-UV exposure of human eyes after cataract surgery

  1. Introduction to designing information and organizations with a positive lens

    NARCIS (Netherlands)

    Avital, M.; Boland, R.J.; Lyytinen, K.


    The role and potential contribution of a positive lens to the design of systems and organizations is the focus of this introductory essay. The positive lens refers to a perspective in the social sciences that emphasizes the capacity of people and organizations to construct better work environments,

  2. Isofocusing and immunological investigations on cephalopod lens proteins

    NARCIS (Netherlands)

    Brahma, S.K.; Lancieri, M.


    Soluble lens proteins from Octopus vulgaris, Sepia officinalis, and Loligo vulgaris were analyzed by thin-layer isoelectric focusing and compared by various immunochemical methods using antibodies directed against total soluble lens protein antigens from the said three species. The results show


    NARCIS (Netherlands)

    Tan, H. Stevie; Mura, Marco; Oberstein, Sarit Y. Lesnik; Bijl, Heico M.


    Purpose: To describe the incidence and outcome of retinal breaks in vitrectomy for retained lens fragments. Methods: This is a retrospective noncomparative interventional case series. Medical records of consecutive cases of vitrectomy for retained lens fragments over a period of 4 years were

  4. The NNEST lens non native english speakers in TESOL

    CERN Document Server

    Mahboob, Ahmar


    The NNEST Lens invites you to imagine how the field of TESOL and applied linguistics can develop if we use the multilingual, multicultural, and multinational perspectives of an NNEST lens to re-examine our assumptions, practices, and theories in the field

  5. The "Youth Lens": Analyzing Adolescence/ts in Literary Texts (United States)

    Petrone, Robert; Sarigianides, Sophia Tatiana; Lewis, Mark A.


    Drawing from interdisciplinary scholarship that re-conceptualizes adolescence as a cultural construct, this article introduces a "Youth Lens." A "Youth Lens" comprises an approach to textual analysis that examines how ideas about adolescence and youth get formed, circulated, critiqued, and revised. Focused specifically on its…

  6. Optimized lens-sparing treatment of retinoblastoma with electron beams

    NARCIS (Netherlands)

    Steenbakkers, RJHM; Altschuler, MD; DAngio, GJ; Goldwein, JW; Kassaee, A


    Purpose: The ideal lens-sparing radiotherapy technique for retinoblastoma calls for 100% dose to the entire retina including the ora serrata and zero dose to the lens, Published techniques, most of which use photons, have not accomplished this ideal treatment. We describe here a technique that

  7. A Broadband Metasurface-Based Terahertz Flat-Lens Array

    KAUST Repository

    Wang, Qiu


    A metasurface-based terahertz flat-lens array is proposed, comprising C-shaped split-ring resonators exhibiting locally engineerable phase discontinuities. Possessing a high numerical aperture, the planar lens array is flexible, robust, and shows excellent focusing characteristics in a broadband terahertz frequency. It could be an important step towards the development of planar terahertz focusing devices for practical applications.

  8. Prevalence of corneal ulcer among contact lens wearers in Nigeria ...

    African Journals Online (AJOL)

    Corneal Ulceration has been described as the most serious complication of contact lens wear worldwide. The incidence of corneal ulceration in contact lens wearers in Nigeria was determined retrospectively. 1759 case notes of patients who had worn contact lenses for at least one year were obtained from eye clinics in ...

  9. Incidence of contact lens-associated microbial keratitis

    NARCIS (Netherlands)

    Cheng, K.H.; Leung, S.L.; Hoekman, J.W.; Beekhuis, W.H.; Mulder, P.G.H.; Geerards, A.J.M.; Kijlstra, A.


    Background. The incidence of contact-lens-associated microbial keratitis is uncertain and its related morbidity in the general population of contact-lens wearers is not known. We examined these issues in a prospective epidemiological study. Methods. We surveyed all practising ophthalmologists in the

  10. Automated Artifact Rejection for Transient Identification in WFC3 IR Image Subtractions (United States)

    Luther, Kyle; Boone, Kyle; Hayden, Brian; Aldering, Greg Scott; Perlmutter, Saul; Supernova Cosmology Project


    We describe a set of features for identifying z>1 supernovae in reference-subtracted HST WFC3 IR images produced by the Supernova Cosmology Project's pipeline for the "See Change" project. These features, in combination with a random forest classifier, yield an effective system for automatically discriminating between supernovae and image artifacts produced by the instrumentation and the image processing procedure. When k-fold cross-validation is performed using a set of 30,000 artifacts and 10,000 synthetic supernovae, the classifier gives an efficiency comparable to that of a human scanner, correctly identifying 97 percent of the synthetic supernovae while rejecting 95 percent of the artifacts. This software will allow for less labor-intensive transient search procedures by automatically rejecting artifacts that would otherwise require human review.

  11. Standardization and Correction of Artifacts in Atom-Probe Tomographic Analysis of Allende Nanodiamonds (United States)

    Lewis, J. B.; Isheim, D.; Moutanabbir, O.; Floss, C.; Seidman, D. N.


    We use complementary atom-probe tomography and secondary ion mass spectrometry to measure the 12C/13C isotopic ratios of meteoritic nanodiamonds and thus determine their origins. We are investigating and quantifying instrumental artifacts.

  12. The use of chitosan in protecting wooden artifacts from damage by mold fungi

    Directory of Open Access Journals (Sweden)

    Rehab El-Gamal


    Conclusions: The growth of fungi on the treated wood samples decreased with increasing the concentration of chitosan. Hence, it was demonstrated that chitosan prevented fungal growth, and its use could be recommended for the protection of archeological wooden artifacts.

  13. Do Martian Blueberries Have Pits? -- Artifacts of an Early Wet Mars (United States)

    Lerman, L.


    Early Martian weather cycles would have supported organic chemical self-organization, the assumed predecessor to an independent "origin" of Martian life. Artifacts of these processes are discussed, including the possibility that Martian blueberries nucleated around organic cores.

  14. Muscle artifact suppression using independent-component analysis and state-space modeling. (United States)

    Santillán-Guzmán, Alina; Heute, Ulrich; Stephani, Ulrich; Galka, Andreas


    In this paper, we aim at suppressing the muscle artifacts present in electroencephalographic (EEG) signals with a technique based on a combination of Independent Component Analysis (ICA) and State-Space Modeling (SSM). The novel algorithm uses ICA to provide an initial model for SSM which is further optimized by the maximum-likelihood approach. This model is fitted to artifact-free data. Then it is applied to data with muscle artifacts. The state space is augmented by extracting additional components from the data prediction errors. The muscle artifacts are well separated in the additional components and, hence, a suppression of them can be performed. The proposed algorithm is demonstrated by application to a clinical epilepsy EEG data set.

  15. Archaeology Through Computational Linguistics: Inscription Statistics Predict Excavation Sites of Indus Valley Artifacts. (United States)

    Recchia, Gabriel L; Louwerse, Max M


    Computational techniques comparing co-occurrences of city names in texts allow the relative longitudes and latitudes of cities to be estimated algorithmically. However, these techniques have not been applied to estimate the provenance of artifacts with unknown origins. Here, we estimate the geographic origin of artifacts from the Indus Valley Civilization, applying methods commonly used in cognitive science to the Indus script. We show that these methods can accurately predict the relative locations of archeological sites on the basis of artifacts of known provenance, and we further apply these techniques to determine the most probable excavation sites of four sealings of unknown provenance. These findings suggest that inscription statistics reflect historical interactions among locations in the Indus Valley region, and they illustrate how computational methods can help localize inscribed archeological artifacts of unknown origin. The success of this method offers opportunities for the cognitive sciences in general and for computational anthropology specifically. Copyright © 2015 Cognitive Science Society, Inc.

  16. Mineral raw materials used in the archaeological artifacts in Guayacas - Dayman - Paysandu

    International Nuclear Information System (INIS)

    Capdepont, I.; Del Puerto, L.; Castineira, C.; Pineiro, G.


    The purpose of this work is about the election, exploitation and modes of supply mineral raw resources used in the manufacturing of lithic and ceramic archaeological artifacts in Guayacas - Dayman - Paysandu

  17. Mitigation of Selected Hanford Site Manhattan Project and Cold War Era Artifacts

    International Nuclear Information System (INIS)

    Prendergast-Kennedy, Ellen L.; Harvey, David W.


    This document is the first time that Manhattan Project and Cold War era artifacts from the Hanford Site have been assembled within a publication. The publication presents photographic and written documentation of a number of Manhattan Project and Cold War era artifacts that were identified and tagged during assessment walk throughs of historic buildings on the Hanford Site but which could not be curated within the Hanford collection because they were too large for long-term storage and/or exhibit purposes or were radiologically contaminated. The significance of the artifacts in this publication and a proposed future appendix is based not on the individual significance of any single artifact but on their collective contribution to the science and engineering of creating plutonium and advancing nuclear technology in nuclear fuel and power.

  18. Are Movement Artifacts in Magnetic Resonance Imaging a Real Problem?—A Narrative Review

    Directory of Open Access Journals (Sweden)

    Inger Havsteen


    Full Text Available Movement artifacts compromise image quality and may interfere with interpretation, especially in magnetic resonance imaging (MRI applications with low signal-to-noise ratio such as functional MRI or diffusion tensor imaging, and when imaging small lesions. High image resolution has high sensitivity to motion artifacts and often prolongs scan time that again aggravates movement artifacts. During the scan fast imaging techniques and sequences, optimal receiver coils, careful patient positioning, and instruction may minimize movement artifacts. Physiological noise sources are motion from respiration, flow and pulse coupled to cardiac cycles, from the swallowing reflex and small spontaneous head movements. Par example, in resting-state functional MRI spontaneous neuronal activity adds 1–2% of signal change, even under optimal conditions signal contributions from physiological noise remain a considerable fraction hereof. Movement tracking during imaging may allow for prospective correction or postprocessing steps separating signal and noise.

  19. Experimental study on metal artifacts caused by dental materials in magnetic resonance imaging

    International Nuclear Information System (INIS)

    Fujitani, Tomio; Yotsui, Yoritaka; Koseki, Yonoshin


    We analyzed metallic artifacts in magnetic resonance images (MRI) caused by 14 dental crowns made of NiCr alloy. Three MRI sequences (fast spin echo (FSE)-3D, FSE-2D and spin echo (SE)-2D) were taken of anterior and posterior cast crowns combined in various arrangements. We observed the shape and volume of the resulting metallic artifacts using multi-planer and three-dimensional reconstructions from the slice data. The metallic artifacts were divided into three signal intensities: high, intermediate and low. The shape of the crown, which was in the center of the artifact, could be detected in the area of low signal intensity. An area of high signal intensity existed only in the frequency direction of the metallic crowns in the slice data. An area of intermediate signal intensity extended widely vertically and horizontally. The high signal intensity area increased in volume as the number of crowns increased. (author)

  20. An evaluation on magnetic resonance imaging of the metallic artifacts, 1

    International Nuclear Information System (INIS)

    Kikumoto, Yoshiaki; Tomura, Kiminori


    This report evaluates a variety of dental materials with respect to MR imaging artifacts in vitro. The increasing use of MR imaging as a clinical method necessitates a study of artifacts that may appear on these images. A wide variety of metallic materials are used in the dentistry and some can potentially cause distortion of MR images. MR imaging was performed using a superconductive magnetom of 1.5 Tesra (Magnetom; Simens). Imaging was obtained with the use of a single 4-mm thick slice two-dimensional Fourier transform rapid technique. Pulse sequence was obtained by Flash method at flip angle=90, echo delay (TE)=10 ms, repetition time (TR)=400 ms. The following results were obtained; Titanium, gold and high nickel content dental materials produced no discernible artifacts. Stainless steel alloys caused major imaging artifacts. (author)