Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses

Directory of Open Access Journals (Sweden)

Ohyun Kwon

2012-05-01

Full Text Available The bisphosphine-catalyzed double-Michael addition of dinucleophiles to electron-deficient acetylenes is an efficient process for the synthesis of many nitrogen-containing heterocycles. Because the resulting heterocycles contain at least one stereogenic center, this double-Michael reaction would be even more useful if an asymmetric variant of the reaction were to be developed. Aminophosphines can also facilitate the double-Michael reaction and chiral amines are more readily available in Nature and synthetically; therefore, in this study we prepared several new chiral aminophosphines. When employed in the asymmetric double-Michael reaction between ortho-tosylamidophenyl malonate and 3-butyn-2-one, the chiral aminophosphines produced indolines in excellent yields with moderate asymmetric induction.

Michael Roitmann : Kalandus ei ole Eestile ilmselt prioriteetne valdkond / Michael Roitmann ; interv. Marko Saaret

Index Scriptorium Estoniae

Roitmann, Michael

2003-01-01

Ilmunud ka: Delovõje Vedomosti 3. dets. lk. 9. Euroopa Komisjoni kalandusdirektoraadi koordinaator Euroopa Liidu laienemise küsimuses Michael Roitmann juhib tähelepanu Eesti kalanduse suurematele probleemidele ning prognoosib EL-iga liitumise mõju Eesti kalandussektori arengule

Book Review: Invitation to Topological Robotics by Michael Farber

DEFF Research Database (Denmark)

Raussen, Martin

2009-01-01

Book Review: Invitaton to Topological Robotics by Michael Farber. Zurich Lectures in Advanced Mathematics, European Mathematical Society (2008), ISBN 978-3-03719-054-8......Book Review: Invitaton to Topological Robotics by Michael Farber. Zurich Lectures in Advanced Mathematics, European Mathematical Society (2008), ISBN 978-3-03719-054-8...

Michael Faraday vs. the Spiritualists

Science.gov (United States)

Hirshfeld, Alan

2006-12-01

In the 1850s, renowned physicist Michael Faraday launched a public campaign against pseudoscience and spiritualism, which were rampant in England at the time. Faraday objected especially to claims that electrical or magnetic forces were responsible for paranormal phenomena, such as table-spinning and communication with the dead. Using scientific methods, Faraday unmasked the deceptions of spiritualists, clairvoyants and mediums and also laid bare the credulity of a public ill-educated in science. Despite his efforts, Victorian society's fascination with the paranormal swelled. Faraday's debacle anticipates current controversies about public science education and the interface between science and religion. This episode is one of many described in the new biography, The Electric Life of Michael Faraday (Walker & Co.), which chronicles Faraday's discoveries and his unlikely rise from poverty to the pinnacle of the English science establishment.

Michael Tomasello: Award for Distinguished Scientific Contributions.

Science.gov (United States)

2015-11-01

The APA Awards for Distinguished Scientific Contributions are presented to persons who, in the opinion of the Committee on Scientific Awards, have made distinguished theoretical or empirical contributions to basic research in psychology. One of the 2015 award winners is Michael Tomasello, who received this award for "outstanding empirical and theoretical contributions to understanding what makes the human mind unique. Michael Tomasello's pioneering research on the origins of social cognition has led to revolutionary insights in both developmental psychology and primate cognition." Tomasello's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

Following Michael Faraday's Footprints

Science.gov (United States)

Galeano, Javier

2011-01-01

Last fall I had the good fortune of receiving financial support to shoot a documentary about Michael Faraday. I took the opportunity to learn more about this great experimentalist and to visit the highlights of places in his life. In this paper, I would like to share a list and description of some of the most remarkable places in London suitable…

Obituary: Michael James Ledlow, 1964-2004

Science.gov (United States)

Puxley, Philip John; Grashuis, Randon M.

2004-12-01

Michael James Ledlow died on 5 June 2004 from a large, unsuspected brain tumor. Since 2000 he had been on the scientific staff of the Gemini Observatory in La Serena, Chile, initially as a Science Fellow and then as a tenure-track astronomer. Michael was born in Bartlesville, Oklahoma on 1 October 1964 to Jerry and Sharon Ledlow. He obtained his Bachelor Degree in astrophysics at the University of Oklahoma in 1987 and attended the University of New Mexico for his graduate work, obtaining his PhD while studying Galaxy Clusters under Frazer Owen in 1994. From 1995-1997 Michael held a postdoctoral position with Jack Burns at New Mexico State University where he used various astronomical facilities including the VLA and Apache Point Observatory to study distant galaxies. From 1998-2000 Michael rejoined the Physics and Astronomy Department at the University of New Mexico where he was a visiting professor until he moved on to Gemini. At the Gemini Observatory, Mike shared in the excitement, hard work and many long days and nights associated with bringing on-line a major new astronomical facility and its instrumentation. Following its commissioning he assisted visiting observers, supported and took data for many more remote users via the queue system, and for each he showed the same care and attention to detail evident in his own research to ensure that all got the best possible data. His research concentrated on the radio and optical properties of galaxy clusters, especially rich Abell clusters such as A2125, on luminous radio galaxies, including the detection of a powerful double radio source in the "wrong sort of galaxy," the spiral system 0313-192, and on EROs (extremely red objects), dusty galaxies barely detectable at optical wavelengths. Michael thoroughly enjoyed living in Chile and enthusiastically immersed himself in the culture of his surroundings. He and his family were actively involved with the International English Spanish Association in La Serena. He had a

Interview with Michael Apple: The Biography of a Public Intellectual

Science.gov (United States)

Peters, Michael A.

2015-01-01

Michael W. Apple is the John Bascom Professor of Curriculum and Instruction and Educational Policy Studies in the Departments of Curriculum and Instruction (CI) and Educational Policy Studies (EPS) at the University of Wisconsin-Madison School of Education where he has taught since 1970. Michael Apple is one of the foremost educational theorists…

Michael Faraday, media man.

Science.gov (United States)

Fara, Patricia

2006-03-01

Michael Faraday was an enthusiastic portrait collector, and he welcomed the invention of photography not only as a possible means of recording observations accurately, but also as a method for advertising science and its practitioners. This article (which is part of the Science in the Industrial Revolution series) shows that like many eminent scientists, Faraday took advantage of the burgeoning Victorian media industry by posing in various roles.

En bog om Michael Strunge

DEFF Research Database (Denmark)

Mai, Anne-Marie

Antologi med bidrag om Michael Strunges forfatterskab. Bidrag af Anne-Marie Mai, Jørgen Aabenhus, Marianne Stidsen, Moritz Schramm, Tue Andersen Nexø, Lars Bukdahl, Jon Helt Haarder, Rune Kühl er optaget efter fagfællesbedømmelse. Antologien er redigeret af Anne-Marie Mai og Jørgen Aabenhus....

Michael Polanyi: Patriarch of Chemical Dynamics and Tacit Knowing.

Science.gov (United States)

Herschbach, Dudley R

2017-03-20

Connecting Science and the Humanities was the title of the symposium on Michael Polanyi that took place at the Technische Universität Berlin (Technical University of Berlin) in October 2016. This essay, which appraises the scientific and philosophical contributions of Michael Polanyi, is based on the presentation given by Dr. Herschbach on this occasion. In the photograph: Polanyi in 1931. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

The power of virtual integration: an interview with Dell Computer's Michael Dell. Interview by Joan Magretta.

Science.gov (United States)

Dell, M

1998-01-01

Michael Dell started his computer company in 1984 with a simple business insight. He could bypass the dealer channel through which personal computers were then being sold and sell directly to customers, building products to order. Dell's direct model eliminated the dealer's markup and the risks associated with carrying large inventories of finished goods. In this interview, Michael Dell provides a detailed description of how his company is pushing that business model one step further, toward what he calls virtual integration. Dell is using technology and information to blur the traditional boundaries in the value chain between suppliers, manufacturers, and customers. The individual pieces of Dell's strategy--customer focus, supplier partnerships, mass customization, just-in-time manufacturing--may be all be familiar. But Michael Dell's business insight into how to combine them is highly innovative. Direct relationships with customers create valuable information, which in turn allows the company to coordinate its entire value chain back through manufacturing to product design. Dell describes how his company has come to achieve this tight coordination without the "drag effect" of ownership. Dell reaps the advantages of being vertically integrated without incurring the costs, all the while achieving the focus, agility, and speed of a virtual organization. As envisioned by Michael Dell, virtual integration may well become a new organizational model for the information age.

Video interview with Michael Dell

CERN Multimedia

CERN Bulletin

2010-01-01

Michael Dell, founder and presently Chairman of the Board of Directors and Chief Executive Office of the DELL computer company visited CERN on Tuesday 26th January 2010. The Bulletin and the Video productions team had the opportunity to meet him. The video interview is transcribed for your convenience.   Michael S. Dell with CERN Director-General Rolf Heuer. What motivated you to come and visit CERN? I obviously heard about the great science and research has going on here, and DELL is very pleased to be a partner and providing a lot of the computers to analyse the data and I really wanted to see for myself in person, some of the great science that is going on here. What is your view on fundamental research in IT, and in general? I think if you look at the field of science in the last hundred years, we have been able to solve a lot of problems, but there are still lots of unsolved problems and unsolved mysteries. And it is only through basic fundamental research that we will address these probl...

Reflections on Michael Hardt and Antonio Negri’s Book “Assembly”

Directory of Open Access Journals (Sweden)

Christian Fuchs

2017-10-01

Full Text Available This contribution presents reflections on Michael Hardt and Antonio Negri’s book “Assembly” (2017, Oxford: Oxford University Press, ISBN 978-0190677961. Keywords: assembly, Michael Hardt, Antonio Negri, multitude, common, entrepreneurship of the multitude, the new Prince, digital capitalism, digital assemblage, neoliberalism, finance

Radiation curable Michael addition compounds

International Nuclear Information System (INIS)

Gruber, G.W.; Friedlander, C.B.; McDonald, W.H.; Dowbenko, R.

1979-01-01

Radiation polymerizable acrylyloxy-containing reaction products are provided from Michael addition reaction of an amide containing at least two acrylate groups with a primary or secondary amine. The resulting amine adducts of the amide, which contain at least one acrylate group per molecule, possesses high cure rates in air and are useful in compositions for forming coatings. (author)

Markets, Marx, Modernity and Mathematics Education: A Response to Michael Apple.

Science.gov (United States)

Gates, Peter

This paper is a response to Michael Apple's paper, "What Postmodernists Forget: Cultural Capital and Official Knowledge." The paper advocates Michael's identification of the current dangers and processes of the growth of new right ideologies in the development of subjectivity, society, and education. The differences in success in the education…

Asymmetric Michael Addition Mediated by Chiral Ionic Liquids.

Science.gov (United States)

Suzuki, Yumiko

2018-06-01

Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines.

Aza-Michael reaction: achievements and prospects

International Nuclear Information System (INIS)

Rulev, Alexander Yu

2011-01-01

Data published in the last 10 years on the use of the aza-Michael reaction in organic synthesis are described systematically. The attention is focused on environmentally friendly processes following green chemistry principles and on methods for the synthesis of compounds that are difficult to access by other routes.

Michael Jackson's Sound Stages

OpenAIRE

Morten Michelsen

2012-01-01

In order to discuss analytically spatial aspects of recorded sound William Moylan’s concept of ‘sound stage’ is developed within a musicological framework as part of a sound paradigm which includes timbre, texture and sound stage. Two Michael Jackson songs (‘The Lady in My Life’ from 1982 and ‘Scream’ from 1995) are used to: a) demonstrate the value of such a conceptualisation, and b) demonstrate that the model has its limits, as record producers in the 1990s began ignoring the conventions of...

Studying Teachers and Schools: Michael Pressley's Legacy and Directions for Future Research

Science.gov (United States)

Mohan, Lindsey; Lundeberg, Mary A.; Reffitt, Kelly

2008-01-01

Much of Michael Pressley's work during the past decade focused on the nature of highly effective, engaging literacy instruction. Michael Pressley believed that studying effective teachers and schools had the potential to influence more engaging and effective teaching, especially in underresourced schools. First, we describe the grounded…

En memoria de Michael Jiménez (1948-2001

Directory of Open Access Journals (Sweden)

Mauricio Archila Neira

2001-01-01

Full Text Available El 1 de septiembre de 2001 murió el historiador Michael Jiménez. Su apellido provenía de España de donde emigró su abuelo en busca de mejor suerte al otro lado del Atlántico. Nacido en el pequeño pueblo de Merced, California (Estados Unidos en agosto de 1948 en el seno de una familia obrera, Michael vivió su infancia en Colombia. A fines de ese año, su padre se desplazó a estas tierras para ser funcionario de la Texas, una multinacional petrolera que tenía sus reales en Puerto Boyacá. Michael estudió en el colegio Nueva Granada -becado por la Texas- hasta los catorce años. En dicho colegio fue compañero de pupitre de Herbert Braun, descendiente a su vez de una familia de emigrantes a Colombia, y con quien la vida lo juntaría de nuevo en las tierras del norte y en oficios similares.

Asymmetric Michael Addition Mediated by Chiral Ionic Liquids

Science.gov (United States)

Suzuki, Yumiko

2018-01-01

Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines. PMID:29861702

Tribute to Professor Anthony J. McMichael

Directory of Open Access Journals (Sweden)

Ashwin Swaminathan

2014-11-01

Full Text Available Emeritus Professor A. J. “Tony” McMichael (1942–2014 was an internationally renowned and pioneering Australian academic and advocate in epidemiology, who was passionate about understanding the influences of the environment on human health. In an illustrious career spanning more than four decades, he made significant contributions to the scientific community and policy discourse—including ground-breaking research related to the health of children. McMichael was a prolific academic writer with over 300 peer-reviewed papers; 160 book chapters and two sole-authored books. However, his outstanding talent was for integrating complex and seemingly unrelated strands from the environmental and health sciences into a cohesive narrative—and highlighting its relevance to lay persons, scientists and governments alike. He was instrumental in validating this nascent field of research and inspiring many others to follow his lead.

Michael Heyrovsky, in memoriam (1932-2017)

Czech Academy of Sciences Publication Activity Database

Barek, J.; Černý, Slavoj; Herman, Zdeněk; Jindra, Jiří; Paleček, Emil

2017-01-01

Roč. 29, č. 8 (2017), s. 2001-2002 ISSN 1040-0397 Institutional support: RVO:68378114 ; RVO:61388955 ; RVO:68081707 Keywords : Michael Heyrovský Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings) Impact factor: 2.851, year: 2016

75 FR 62635 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Science.gov (United States)

2010-10-12

... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... determine patients' satisfaction with services provided by or through the Michael E. DeBakey Home Care...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

Aza-Michael Mono-addition Using Acidic Alumina under Solventless Conditions

Directory of Open Access Journals (Sweden)

Giovanna Bosica

2016-06-01

Full Text Available Aza-Michael reactions between primary aliphatic and aromatic amines and various Michael acceptors have been performed under environmentally-friendly solventless conditions using acidic alumina as a heterogeneous catalyst to selectively obtain the corresponding mono-adducts in high yields. Ethyl acrylate was the main acceptor used, although others such as acrylonitrile, methyl acrylate and acrylamide were also utilized successfully. Bi-functional amines also gave the mono-adducts in good to excellent yields. Such compounds can serve as intermediates for the synthesis of anti-cancer and antibiotic drugs.

Professor Michael Levitt

Directory of Open Access Journals (Sweden)

Gemma-Louise Davies

2015-10-01

Full Text Available Professor Michael Levitt (Stanford University, USA won the 2013 Nobel Prize in Chemistry for the development of multiscale models for complex chemical systems—computational tools which can calculate the course of chemical reactions. Professor Levitt was born in Pretoria, South Africa; he came to the UK on a summer vacation aged 16, where he decided to stay and study for his A‑levels. His interest in the physics of living systems drove him to study biophysics at King’s College London, before securing a PhD position at the Laboratory of Molecular Biology in Cambridge. In the interim year between his degree and beginning his PhD, Professor Levitt worked at the Weizmann Institute of Science in Israel, where he met his future wife. They married later that year and moved to Cambridge, where their three children were born. After completing his PhD, he spent time working in Israel, Cambridge, the Salk Institute and Stanford (both California. Since 1986, he has split his time between Israel and California. Outside of science, he is a keen hiker and he is well-known to have attended the eclectic ‘Burning Man’ Festival in California.[1] Professor Levitt visited the University of Warwick to speak at the Computational Molecular Science Annual Conference in March 2015. In this interview, Dr Gemma-Louise Davies, an Institute of Advanced Study Global Research Fellow, spoke to Professor Levitt about the importance of Interdisciplinarity in his field, role models in Academia, and his plans for the future. Image: Professor Michael Levitt (left with Dr Scott Habershon (right, organiser of the 2015 Computational Molecular Science Annual Conference during his visit to the University of Warwick in March 2015. [1] ‘Burning Man’ is a unique annual festival dedicated to community, art, music, self-expression and self-reliance. Tens of thousands of people flock to this temporary metropolis built in the Californian desert.

SuchThatCast Episode 6: Michael Boylan

NARCIS (Netherlands)

Soraker, Johnny

2012-01-01

Michael Boylan is the John J. McDonnell jr chair in Ethics, and professor and chair of the philosophy department at Marymount University in Arlington, Virginia. In addition to being a poet and novelist, he has written more than 100 published articles and 25 books primarily in ethics, social and

Double Michael Addition Reaction of Bischalcone under Ultrasound

Institute of Scientific and Technical Information of China (English)

LI,Ji-Tai; XU,Wen-Zhi; CHEN,Guo-Feng; LI,Tong-Shuang

2004-01-01

@@ The Michael addition of 1,5-diaryl-1,4-pentadien-3-ones with active methylene compounds has been the subjects of many investigations. Ultrasound has increasingly been used in organic synthesis in the last three decades. Compared with traditional methods, this method is more convenient and easily controlled. A large number of organic reactions can be carried out in higher yield, shorter reaction time or milder conditions under ultrasonic irradiation. KF/Al2O3 as a useful solid supported catalyst has received considerable attention because of their high level of chemoselectivity and environmental compatibility as well as simplicity of operation and their ready availability at low cost. Herein we report the double Michael addition of dibenzalacetone with active methlene compounds such as dimethyl malonate, diethyl malonate,methyl cyanoacetate and ethyl cyanoacetate catalyzed by KF/Al2O3 under ultrasound irradiation.

Michael Frayn visits CERN

CERN Multimedia

2007-01-01

Award-winning playwright and novelist Michael Frayn gave a guest lecture in the main auditorium at CERN on Friday 15 March about his new book The Human Touch: Our Part in the Creation of the Universe. The lecture focused on cosmology and philosophy and the limitations that language places on our ability to understand the creation of a universe in which we seem to play such a small part. In addition to his novels and plays, which include Copenhagen, a play about the 1941 meeting between German physicist Werner Heisenberg and Danish physicist Niels Bohr, Frayn has translated several works from Russian, including plays by Chekhov and Tolstoy.

Between Irish National Cinema and Hollywood: Neil Jordan’s Michael Collins

Directory of Open Access Journals (Sweden)

Raita Merivirta-Chakrabarti

2007-03-01

Full Text Available When Neil Jordan’s film Michael Collins was released in 1996, it was seen by some as a Hollywood epic, by others as a great national film. I would argue that Michael Collins combines these two traditions and occupies a space between Irish national cinema and Hollywood. The subject matter, the creative talent and the locations were Irish and the film was produced by using the Irish filmmaking infrastructure and the Irish government’s support mechanisms, but it was largely financed and distributed by a Hollywood studio. Also, to make it more appealing especially globally, but probably also locally (since Hollywood is now the international standard, it makes use of Hollywood conventions, making it accessible to international audiences as well. Despite the Hollywood mode, the fact remains that Michael Collins is a national film text, and Jordan does not make too many concessions to the non-Irish audiences.

Reframing Michael Scott: Exploring Inappropriate Workplace Communication

Science.gov (United States)

Schaefer, Zachary A.

2010-01-01

Individuals who work in professional settings interact with others who may exhibit a variety of cultural beliefs and decision-making approaches. Page (2007) argues that cognitive diversity (i.e., how people approach and attempt to solve problems) is a vital asset in effective organizations. Michael Scott, who portrays the inept main character on…

Michael Moore kaevati kohtusse pettuse eest / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2006-01-01

Dokumentaalfilm "9/11 Fahrenheiti" ("Fahrenheit 9/11") : režissöör Michael Moore : USA 2004. Iraagi sõja invaliidistunud veteran andis režissööri kohtusse teda kujutavate flmikaadrite loata ja tenentsliku kasutamise pärast

Michael Haneke film Euroopa parim / M. T.

Index Scriptorium Estoniae

M. T.

2005-01-01

IX PÖFFil linastuv Michael Haneke film "Varjatud" ("Cache") võitis laupäeval mitu Euroopa Filmiakadeemia auhinda, selhulgas parima filmi, parima lavastaja, parima meesnäitleja (Daniel Auteuil) ja FIPRESCI auhinna. Parim naisnäitleja - Julia Jentsch ("Sophie Scholli viimased päevad"), operaator - Franz Lustig ("Don't Come Knocking"), stsenaarium - Hany Abu-Assad, Bero Beyer ("Kohe paradiisi")

Brändi näkyy musiikkivideossa : Esimerkkitapaus Michael Jackson

OpenAIRE

Kontinen, Noora

2016-01-01

Tutkin opinnäytetyössäni brändin ja musiikkivideon suhdetta toisiinsa. Työssä käsitellään lyhyesti myös tähteyttä. Esittelen ensin vähän historiaa ja peruskäsitteitä, minkä jälkeen käytän Michael Jacksonin Billie Jean -musiikkivideota esimerkkinä tutkiessani Michael Jacksonin brändiä. Teoksessa käytetään lähdeaineistoa sekä omaa analyysia. Keskityn tarkastelemaan musiikkivideoita, ja niihin liittyviä sisältöjä yleisesti, ei niinkään teknisesti. Toivon, että työstäni on apua jollekin,...

Michael Goodsite gæsteprofessor på Thunderbird School of Global Management

DEFF Research Database (Denmark)

Pedersen, Jens Christian

2010-01-01

Professor Michael Goodsite er blevet udnævnt til "Visiting Professor of Global Processes and Senior Research Fellow in Climate Strategy" ved Thunderbird School of Global Management, som har verdens højst rangerede MBA uddannelse inden for international handel.......Professor Michael Goodsite er blevet udnævnt til "Visiting Professor of Global Processes and Senior Research Fellow in Climate Strategy" ved Thunderbird School of Global Management, som har verdens højst rangerede MBA uddannelse inden for international handel....

Correspondence of Michael Faraday, v.5 1855-1860

CERN Document Server

Faraday, Michael

2008-01-01

This volume includes 70% of previously unpublished letters of Michael Farday spanning half of the 1850s and most of 1860. Topics include Faraday's work on regelation, the transmission of light through gold and his appointment by Emperor Napoleon III to be a Commander of the Legion of Honour.

Michael Jackson antes del caos

OpenAIRE

Juan Luciano Nieves

2015-01-01

Michael Jackson es un buen ejemplo de cómo utilizar las relaciones públicas para realizar o manipular la imagen de un producto a través de los medios de comunicación. Este ensayo pretende analizar los eventos que tuvieron lugar antes de que el cantante fuera acusado de abuso sexual contra un menor. Dichos eventos formaron parte de un plan muy bien delineado para disminuir los efectos de la inminente crisis que se acercaba. Este trabajo combina la crítica retórica de temas de fantasía con teor...

Eesti luksushotellide ristiisa / Michael Stenner ; interv. Malle Koido

Index Scriptorium Estoniae

Stenner, Michael

2007-01-01

Eesti tipphotelle 1997. aastast juhtinud sakslane, praegu hotellide Kolm Õde ja Telegraaf juht räägib Eesti ja Saksamaa erinevustest, Eesti hotelliärist, teeninduskultuurist ja personalist. Lisa: Kes on Michael Stenner ning kuidas ta Eestisse sattus? Ilmunud ka: Linnaleht : Pärnu, 23. veebr. 2007, lk. 5-6

Berliinis võidutses Michael Haneke / Jüri Laulik

Index Scriptorium Estoniae

Laulik, Jüri, 1959-

2005-01-01

IX PÖFFil linastuv Michael Haneke film "Varjatud" ("Cache") võitis laupäeval mitu Euroopa Filmiakadeemia auhinda, sealhulgas parima filmi, parima lavastaja ja parima meesnäitleja (Daniel Auteuil) auhinna. Parima naisnäitleja tiitli pälvis Julia Jentsch ("Sophie Scholli viimased päevad"). Elutööpreemia sai sir Sean Connery

Michael Jackson antes del caos

Directory of Open Access Journals (Sweden)

Juan Luciano Nieves

2015-01-01

Full Text Available Michael Jackson es un buen ejemplo de cómo utilizar las relaciones públicas para realizar o manipular la imagen de un producto a través de los medios de comunicación. Este ensayo pretende analizar los eventos que tuvieron lugar antes de que el cantante fuera acusado de abuso sexual contra un menor. Dichos eventos formaron parte de un plan muy bien delineado para disminuir los efectos de la inminente crisis que se acercaba. Este trabajo combina la crítica retórica de temas de fantasía con teoría de comunicación.

A perspectiva de Michael Apple para os estudos das políticas educacionais

Directory of Open Access Journals (Sweden)

Luís Armando Gandin

Full Text Available Resumo Este artigo tem como objetivo analisar as contribuições de Michael Apple para o campo da pesquisa em políticas educacionais. Na extensa obra de Michael Apple, destacamos seis elementos que podem auxiliar aqueles que estão interessados na área de políticas em educação: o princípio epistemológico da análise relacional; o exame do Estado como relação; a herança de Antonio Gramsci e de Raymond Williams que Michael Apple incorpora no uso de conceitos como hegemonia e senso comum; a análise que Michael Apple faz das políticas educacionais como políticas culturais, como disputas por visão de mundo, como luta por consolidação de uma hegemonia que vai além do econômico; a sua postura de pesquisador; e a capacidade que Michael Apple tem de ir além da lógica da reprodução e determinação para enfatizar o papel da agência e da contra-hegemonia. Através de exemplos práticos da própria obra de Apple e de outras pesquisas empíricas, apresentam-se as implicações de cada um dos seis pontos acima citados para os pesquisadores interessados na área de políticas educacionais. Conclui-se que muitas das contribuições de Apple podem auxiliar em pesquisas nessa área, tendo em vista a discussão que o autor realiza em sua obra e sua crítica ao determinismo econômico nas análises do campo educacional, salientando a importância, assim, de aspectos que estão relacionados à esfera da cultura.

DNA-based catalytic enantioselective intermolecular oxa-Michael addition reactions

NARCIS (Netherlands)

Megens, Rik P.; Roelfes, Gerard

2012-01-01

Using the DNA-based catalysis concept, a novel Cu(II) catalyzed enantioselective oxa-Michael addition of alcohols to enones is reported. Enantioselectivities of up to 86% were obtained. The presence of water is important for the reactivity, possibly by reverting unwanted side reactions such as

Michael Kohlhaas or the Germans and Their Law

Directory of Open Access Journals (Sweden)

Heike Jung

2014-12-01

Full Text Available Asked to pick a single representative ‘German’ piece for a discourse on ‘Law and Literature’ one almost inevitably ends up with Kleist’s tale Michael Kohlhaas. It seems to be the literary incarnation of the German stance vis-à-vis the law. It is all about horses; it could just as well be about dogs. Kohlhaas fights a devastating battle, using legal means and outright violence, even warfare, for their recovery in good shape. Victorious eventually with his legal actions, he is happy to trade in his own life for this victory, thus giving an extreme example for the nice line between being in the right and pursuing this position with disproportionate rigour. Of course, the interpretations of Michael Kohlhaas (which, in its complete version, dates of 1810 have varied from epoch to epoch as well as from reader to reader. It is not possible to rehearse the bulk of ‘Kohlhaas literature’. In comparing legal cultures, it might be of interest to look into the question why such a somber story on the law forms part and will continue to form part of the German cultural heritage. Si se tiene que elegir un único representante “alemán” para una ponencia sobre “derecho y literatura”, es inevitable optar por la obra de Kleist, Michael Kohlhaas. Parece la encarnación literaria de la posición alemana hacia el derecho. El libro trata de caballos; también podría tratar sobre perros. Kohlhaas libra una batalla devastadora usando medios legales y la violencia pura y dura, incluso la guerra, para que se recuperen en buena forma. Finalmente resulta ganador mediante acciones legales, está contento de dedicar su propia vida para conseguir esta victoria, dando así un ejemplo extremo de la línea que existe entre tener la razón y seguir esta posición con un rigor desproporcionado. Por supuesto, las interpretaciones de Michael Kohlhaas (publicado en 1810 han variado de una época a otra, y de un lector a otro. No es posible revisar el grueso de

77 FR 69550 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Science.gov (United States)

2012-11-19

... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY.... DeBakey Home Care Program. DATES: Written comments and recommendations on the proposed collection of...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

76 FR 624 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Science.gov (United States)

2011-01-05

... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... satisfaction with the quality of services/care provided by home care program staff. An agency may not conduct... Form 10-0476).'' SUPPLEMENTARY INFORMATION: Title: Patient Satisfaction Survey Michael E. DeBakey Home...

The conceptualization of love in religious thought of George Florovsky and Michael Pomazansky

Directory of Open Access Journals (Sweden)

Pavenkov Oleg Vladimirovich

2015-04-01

Full Text Available The present article is concerned with the question of conceptualization of love in works of Fr. George Florovsky and Fr. Michael Pomazansky, Russian religious thinkers and theologists. We are studying the meaning and appropriacy of two words, ‘love’ (English and ‘любовь’ (Russian, that are the best to represent the agapelogical positive evaluation in Russian religious thought. Data for study was taken from ten different articles and extracts from books written by Fr. George Florovsky and Fr. Michael Pomazansky. On the basis of this analysis we develop semantic explications of words ‘love’ and ‘любовь’ as Christian spiritual concepts within the framework of theoretical approach of Natural Semantic Metalanguage (NSM. In summary we state that this article discusses, describes and determines some similarities and differences in understanding of concept ‘love’ in the affore-referenced works by Fr. George Florovsky and Fr. Michael Pomazansky.

Arenethiolatecopper(I) complexes as homogeneous catalysts for Michael addition reactions

NARCIS (Netherlands)

Koten, G. van; Klaveren, M. van; Lambert, F.; Eijkelkamp, D.J.F.M.; Grove, D.M.

1994-01-01

Arenethiolatocopper(I) complexes are shown to be efficient homogeneous catalysts in Michael addition reactions of several Grignard reagents to acyclic enones; the addition products are formed with excellent chemoselectivity (>99%) and good enantioselectivity (76% e.e.).

Michael Bloomberg ähvardab USA valimised "ära rikkuda" / Heiki Suurkask

Index Scriptorium Estoniae

Suurkask, Heiki, 1972-

2008-01-01

New Yorgi praegune linnapea Michael Bloomberg võib kolmanda kandidaadina sekkuda presidendikandidaatide valimiskampaaniasse, probleem on aga tema vähene tuntus. Lisa: Seni on riigipeakoha jaganud kaks suurparteid

Professor Porter ja tema viis konkurentsitegurit / Michael E Porter

Index Scriptorium Estoniae

Porter, Michael E

2008-01-01

Maailmas tuntud juhtimisguru Michael Porter viie konkurentsijõu teooriast ja selle rakendatavusest erinevates valdkondades. Lisad: Erinevused valdkondade kasumlikkuses; 5 määravat konkurentsijõudu; Investeeritud kapitali keskmine tasuvus; Mõnede USA tegevusvaldkondade kasumlikkus; Valdkonnaanalüüs praktikas; Valdkonna määratlemine; Valdkonnaanalüüsi sammud

Michael Polanyi on the Education and Knowledge of Scientists.

Science.gov (United States)

Jacobs, Struan

2000-01-01

Explains why teachers addressing the nature of science should know the work of Michael Polanyi. Outlines Polanyi's intellectual career and examines his ideas on the education of scientists, research, and knowledge. Polanyi presaged Kuhn, Feyerabend, and the constructivists, yet insisted that science produces true knowledge about reality. (Contains…

Chinese Middle Classes: Taiwan, Hong Kong, Macao and China. Edited by Hsin-Huang Michael Hsiao

DEFF Research Database (Denmark)

Brødsgaard, Kjeld Erik

2018-01-01

Book review of: Chinese Middle Classes:Taiwan, Hong Kong, Macao and China. Edited by Hsin-Huang Michael Hsiao. Abingdon: Routledge, 2014. Pp. 268. ISBN 10: 1138120847; ISBN 13: 978-1138120846......Book review of: Chinese Middle Classes:Taiwan, Hong Kong, Macao and China. Edited by Hsin-Huang Michael Hsiao. Abingdon: Routledge, 2014. Pp. 268. ISBN 10: 1138120847; ISBN 13: 978-1138120846...

Tweeting Prayers and Communicating Grief over Michael Jackson Online

Science.gov (United States)

Sanderson, Jimmy; Cheong, Pauline Hope

2010-01-01

Death and bereavement are human experiences that new media helps facilitate alongside creating new social grief practices that occur online. This study investigated how people's postings and tweets facilitated the communication of grief after pop music icon Michael Jackson died. Drawing on past grief research, religion, and new media studies, a…

78 FR 6851 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Science.gov (United States)

2013-01-31

... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number: 2900-0775. Type... home care program staff. An agency may not conduct or sponsor, and a person is not required to respond...

A Good Time: A Conversation with C. Michael Nelson

Science.gov (United States)

Zabel, Robert; Kaff, Marilyn; Teagarden, Jim

2015-01-01

C. Michael Nelson began his special education career as a teacher of adolescents with learning and behavior disorders. He has worked as a child psychologist and as a professor with the Department of Special Education and Rehabilitation Counseling at the University of Kentucky. He coordinated the graduate Personnel Preparation Program for Teachers…

Aza-Michael Reaction for an Undergraduate Organic Chemistry Laboratory

Science.gov (United States)

Nigam, Manisha; Rush, Brittney; Patel, Jay; Castillo, Raul; Dhar, Preeti

2016-01-01

A green, aza-Michael reaction is described that can be used to teach undergraduate students conjugate addition of nitrogen nucleophile to an a,ß-unsaturated ester. Students analyze spectral data of the product obtained from the assigned reaction to determine product structure and propose the mechanism of its formation. The experiment requires…

Leadership and creativity in public services: An interview with Lord Michael Bichard, Chair of the National Audit Office

OpenAIRE

Bolden, R.; O'Regan, N.

2018-01-01

This interview with Lord Michael Bichard, one of the most distinguished public sector leaders in the UK, explores his ideas around the relationship between leadership, creativity and innovation. A champion of place-based approaches to public services, where citizens are actively involved in service design, delivery and appraisal, Bichard advocates the need for inclusive and supportive leadership that enables the emergence of the kinds of creativity required to respond to the financial challen...

[An exceptional human relationship (Michael P. Kierkegaard, Søren Kierkegaard)].

Science.gov (United States)

Jacobs, R

1978-01-01

There were a father and a son, Michael and Sören Kierkegaard, both highly talented, imaginitive, witty, humorous, especially interested in shrewd dialectrical dialogues respectively debates, both profound melancholy ponderers. But according to very own individuality their congeniality wasn't absolute. The father, being under a questionable rigorous opinion of sin, suffered from undeserved divine grace since early childhood. And Michael Kierkegaard made Sören anxious with the religious experience of original sin. This anxiety moved (touched or affected) the sensitive son mighty. Nevertheless he should not despair hopelessly like his unlucky father. On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining. That is why Sören Kierkegaard succeeded in sublimation of all psychological and philosophic (al) attitudes (or opinions) in the sphere of religiousness. And the result? A novel philosophy of life: Christian existentialism.

Aza‐Michael addition reaction: Post‐polymerization modification and preparation of PEI/PEG‐based polyester hydrogels from enzymatically synthesized reactive polymers

DEFF Research Database (Denmark)

Hoffmann, Christian; Stuparu, Mihaiela C.; Daugaard, Anders Egede

2015-01-01

The utility of aza‐Michael addition chemistry for post‐polymerization functionalization of enzymatically prepared polyesters is established. For this, itaconate ester and oligoethylene glycol are selected as monomers. A Candida Antarctica lipase B catalyzed polycondensation reaction between the two...... monomers provides the polyesters, which carry an activated carbon‐carbon double bond in the polymer backbone. These electron deficient alkenes represent suitable aza‐Michael acceptors and can be engaged in a nucleophilic addition reaction with small molecular mono‐amines (aza‐Michael donors) to yield...... functionalized linear polyesters. Employing a poly‐amine as the aza‐Michael donor, on the other hand, results in the formation of hydrophilic polymer networks....

New Models at Lasell: Q&A with President Michael Alexander

Science.gov (United States)

Harney, John O.

2018-01-01

The "New England Journal of Higher Education" ("NEJHE") Executive Editor John O. Harney had the chance to catch up with Lasell College President Michael Alexander about the small Newton, Massachusetts, college's plans to challenge the higher education business model. The interview is presented in this article.

New 'Master of Science in Nuclear Engineering' study course launched. Interview with Professor Horst-Michael Prasser; Neuer Studiengang 'Master of Science in Nuclear Engineering' lanciert. Interview mit Professor Horst-Michael Prasser

Energy Technology Data Exchange (ETDEWEB)

Anon.

2008-02-15

In the fall of 2008, the Zurich Technical University (ETH) and the Lausanne EPF will launch their joint master course of studies in Nuclear Engineering. Horst-Michael Prasser, Professor for Nuclear Energy Systems at Zurich ETH, is responsible for designing the course. In this interview he comments, among other things, on fundamental questions which may determine a future student's choice of a course of studies, and on the special opportunities offered by the new Nuclear Engineering course. Other subjects addressed include the renaissance of nuclear power and the future prospects of safety research and new reactor developments. (orig.)

"Alarme de incêndio": Michael Löwy e a crítica ecossocialista da civilização capitalista moderna "Fire alarm": Michael Löwy and the ecosocialist critique of the modern capitalist civilization

Directory of Open Access Journals (Sweden)

Fabio Mascaro Querido

2013-04-01

Full Text Available A emergência da crise ecológica, como sintoma mais nítido de uma verdadeira crise civilizató-ria, impôs novos desafios ao pensamento crítico e, em especial, ao marxismo. Partindo desse pressuposto, o objetivo deste artigo é apresentar a defesa de Michael Löwy de uma radicalização ecossocialista da crítica marxista da modernidade, tarefa para a qual a grande recusa de Walter Benjamin das ideologias do pro- gresso é uma das fontes decisivas de inspiração. Para Michael Löwy, a ruptura com as ideologias do progresso e com o paradigma civilizatório capitalista moderno é uma condição indispensável para a atua-lização ecossocialista do marxismo.The emergence of the ecological crisis as a clearer symptom of a true civilizatory crisis has imposed new challenges to critical thought and, in particular, to Marxism. Based on this assumption, this article aims to present Michael Löwy's defense of an ecosocialist radicalization of the Marxist critique of modernity, a task for which Walter Benjamin's great refusal of the ideologies of progress is one of the critical sources of inspiration. To Michael Löwy, breaking away from the ideologies of progress and from the modern capitalistic civilizatory paradigm is a prerequisite for the ecosocialist updating of Marxism.

N-Heterocyclic Carbene-Catalysed Diastereoselective Vinylogous Michael Addition Reaction of gamma-Substituted deconjugated Butenolides

KAUST Repository

Guo, Hao

2015-11-16

An efficient N-heterocyclic carbene (NHC)-catalysed vinylogous Michael addition of deconjugated butenolides was developed. In the presence of 5 mol% of the NHC catalyst, both γ-alkyl and aryl-substituted deconjugated butenolides undergo vinylogous Michael addition with various α, β-unsaturated ketones, esters, or nitriles to afford γ,γ-disubstituted butenolides containing adjacent quaternary and tertiary carbon centers in good to excellent yields with excellent diastereoselectivities. In this process, the free carbene is assumed to act as a strong Brønsted base to promote the conjugate addition.

N-Heterocyclic Carbene-Catalysed Diastereoselective Vinylogous Michael Addition Reaction of gamma-Substituted deconjugated Butenolides

KAUST Repository

Guo, Hao; Xing, Fen; Du, Guang-Fen; Huang, Kuo-Wei; Dai, Bin; He, Lin

2015-01-01

An efficient N-heterocyclic carbene (NHC)-catalysed vinylogous Michael addition of deconjugated butenolides was developed. In the presence of 5 mol% of the NHC catalyst, both γ-alkyl and aryl-substituted deconjugated butenolides undergo vinylogous Michael addition with various α, β-unsaturated ketones, esters, or nitriles to afford γ,γ-disubstituted butenolides containing adjacent quaternary and tertiary carbon centers in good to excellent yields with excellent diastereoselectivities. In this process, the free carbene is assumed to act as a strong Brønsted base to promote the conjugate addition.

Educational Implications of Michael Fishbane's "Sacred Attunement: A Jewish Theology"

Science.gov (United States)

Marom, Daniel

2008-01-01

This article posits Michael Fishbane's Judaic scholarship as a prime resource for Jewish education. The link between the two fields can be made through a translation of the theological underpinnings of Fishbane's insights into Judaism to educational purposes and practices. Initial work with Jewish educators on establishing this link encouraged…

77 FR 30047 - Notice of Opportunity for Public Comment on Surplus Property Release at Michael J Smith Field...

Science.gov (United States)

2012-05-21

... Comment on Surplus Property Release at Michael J Smith Field, Beaufort, NC AGENCY: Federal Aviation... J Smith Field, be used for aeronautical purposes. DATES: Comments must be received on or before June... property at the Michael J Smith Field. The property consists of one parcel located on the north side of...

Michael Perelman: An ecological future in view of Marxist Economics (Ⅱ)

Institute of Scientific and Technical Information of China (English)

Ren Xiaomei

2009-01-01

@@ Interviewee profile: Michael Perelman, currently professor of Economics Department of California State University, USA, American economist and economic historian with nearly 20 publications in the field of economics criticism, including Railroading Economics, Manufacturing Discontent, The Perverse Economy, and The Invention of Capitalism.

Michael Faraday on the Learning of Science and Attitudes of Mind.

Science.gov (United States)

Crawford, Elspeth

1998-01-01

Makes use of Michael Faraday's ideas on learning, focusing on his attitudes toward the unknowns of science and the development of an attitude that improves scientific decision making. This approach acknowledges that there is an inner struggle involved in facing unknowns. (DDR)

Hexafluorobenzene: A powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reaction

KAUST Repository

Lattanzi, Alessandra; De Fusco, Claudia; Russo, Alessio; Poater, Albert; Cavallo, Luigi

2012-01-01

A dramatic enhancement of the diastereo- and enantioselectivity in the nitro-Michael addition reaction organocatalysed by a commercially available α,α-l-diaryl prolinol was disclosed when performing the reaction in unconventional hexafluorobenzene

Prints Charles ja prints Michael külastasid Tallinna kirikuid / Allan Tammiku

Index Scriptorium Estoniae

Tammiku, Allan

2001-01-01

Prints Charles külastas 6. novembril Eesti-visiidi ajal Tallinna toomkirikut ja Pühavaimu kirikut, prints Michael viibis Tallinnas 11. novembril eravisiidil, ta külastas toomkirikut, Niguliste ja Pühavaimu kirikut

Der Wert von Worten. Michael Serrer aus dem Literaturbüro Düsseldorf im Interview mit der Textpraxis-Redaktion

Directory of Open Access Journals (Sweden)

Michael Serrer

2014-11-01

Full Text Available Die Textpraxis-Redaktion unterhält sich mit Michael Serrer über Literaturvermittlung in Zeiten der Digitalisierung, über Kanonisierung und die Rolle der Literatur in der Gesellschaft. Michael Serrer ist Leiter des Literaturbüros NRW und Feuilletonist.

New 'Master of Science in Nuclear Engineering' study course launched. Interview with Professor Horst-Michael Prasser

International Nuclear Information System (INIS)

Anon.

2008-01-01

In the fall of 2008, the Zurich Technical University (ETH) and the Lausanne EPF will launch their joint master course of studies in Nuclear Engineering. Horst-Michael Prasser, Professor for Nuclear Energy Systems at Zurich ETH, is responsible for designing the course. In this interview he comments, among other things, on fundamental questions which may determine a future student's choice of a course of studies, and on the special opportunities offered by the new Nuclear Engineering course. Other subjects addressed include the renaissance of nuclear power and the future prospects of safety research and new reactor developments. (orig.)

Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

Science.gov (United States)

Black, Donald W

2018-02-01

One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Charles Schulz. Both will be greatly missed.

Reports of the working groups / Eino Tamm, Sahlin Michael, Valve Kirsipuu...[jt.

Index Scriptorium Estoniae

1999-01-01

Töögruppide "EU enlargement and relevant institutional reforms" (juhatajad Eino Tamm, Michael Sahlin) ja "Maintaining of competitiveness of Estonia and other candidate countries" (juhatajad Valve Kirsipuu, Terry Calbom) tööst. Autor: Reformierakond

Joseph and Michael Haydn in the Bohemian music archives. An anniversary tribute

Czech Academy of Sciences Publication Activity Database

Freemanová, Michaela

2012-01-01

Roč. 20, č. 1 (2012), s. 117-126. ISBN 978-3-486-58949-8. ISSN 1865-5696 Institutional support: RVO:68378076 Keywords : Joseph Haydn * Michael Haydn * music archives Subject RIV: AL - Art, Architecture, Cultural Heritage

Entretien avec Michael Quinn Patton | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

9 févr. 2011 ... Michael Quinn Patton, évaluateur de renommée internationale, était récemment au CRDI .... C'est un mode de pensée analytique qui doit tout imprégner. ... des données solides et crédibles sur ce qui marche et ce qui ne marche pas. ... des emplois, des infrastructures et un accès à la nourriture et aux mar.

Organocatalytic Asymmetric Michael Addition of 4-Hydroxycoumarin to β,γ-Unsaturated α-Keto Esters

Energy Technology Data Exchange (ETDEWEB)

Suh, Chang Won; Han, Tae Hyun; Kim, Dae Young [Soonchunhyang Univ., Asan (Korea, Republic of)

2013-06-15

In conclusion, we have developed organocatalytic enantioselective conjugate addition reaction of 4-hydroxycoumarin (1) to β,γ-unsaturated α-keto esters 2 to afford biologically valuable warfarin derivatives 3. The process is efficiently catalyzed by a binaphthyl-modified thiourea organocatalyst. The coumarin core is present as a characteristic structural motif in a large number of natural products and biologically active molecules.1 Particularly, many of these naturally occurring 4-hydroxycoumarin and their synthetic analogues are important precursors for the synthesis of natural products and pharmaceuticals. Enantioselective organocatalytic conjugate addition of 4-hydroxycoumarin to α,β-unsaturated ketones is a straightforward method to access warfarin which is an effective anticoagulants. Although a number of reactions of α,β-unsaturated ketones as Michael acceptors have been reported, the corresponding β,γ-unsaturated α-keto esters have received relatively little attention as Michael acceptors. Recently, several groups have reported the asymmetric Michael addition of 4-hydroxycoumarin to β,γ-unsaturated α-keto esters catalyzed by Cu(II)-bisoxazoline, N,N'-dioxide-Ni(II) complexes, thiourea catalysts. Although several efficient methods have been achieved by these systems, an effective method for the synthesis of warfarin analogues is still a challenge.

Organocatalytic Asymmetric Michael Addition of 4-Hydroxycoumarin to β,γ-Unsaturated α-Keto Esters

International Nuclear Information System (INIS)

Suh, Chang Won; Han, Tae Hyun; Kim, Dae Young

2013-01-01

In conclusion, we have developed organocatalytic enantioselective conjugate addition reaction of 4-hydroxycoumarin (1) to β,γ-unsaturated α-keto esters 2 to afford biologically valuable warfarin derivatives 3. The process is efficiently catalyzed by a binaphthyl-modified thiourea organocatalyst. The coumarin core is present as a characteristic structural motif in a large number of natural products and biologically active molecules.1 Particularly, many of these naturally occurring 4-hydroxycoumarin and their synthetic analogues are important precursors for the synthesis of natural products and pharmaceuticals. Enantioselective organocatalytic conjugate addition of 4-hydroxycoumarin to α,β-unsaturated ketones is a straightforward method to access warfarin which is an effective anticoagulants. Although a number of reactions of α,β-unsaturated ketones as Michael acceptors have been reported, the corresponding β,γ-unsaturated α-keto esters have received relatively little attention as Michael acceptors. Recently, several groups have reported the asymmetric Michael addition of 4-hydroxycoumarin to β,γ-unsaturated α-keto esters catalyzed by Cu(II)-bisoxazoline, N,N'-dioxide-Ni(II) complexes, thiourea catalysts. Although several efficient methods have been achieved by these systems, an effective method for the synthesis of warfarin analogues is still a challenge

Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology

DEFF Research Database (Denmark)

Pors, Niels Ole

2010-01-01

Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology. Medford. Information Today. ASIS&T Monographs, 2009. 185 pages. $ 59.50. ISBN 978-1-57387-373-4......Review: Michael Crandall & Karen E. Fisher (Eds) Digital Inclusion: Measuring the Impact of Information and Community Technology. Medford. Information Today. ASIS&T Monographs, 2009. 185 pages. $ 59.50. ISBN 978-1-57387-373-4...

Michael K. Scullin: Psi Chi/APA Edwin B. Newman Graduate Research Award.

Science.gov (United States)

2011-11-01

Presents Michael K. Scullin as the 2011 winner of the American Psychological Association Psi Chi/APA Edwin B. Newman Graduate Research Award. "For an outstanding research paper that examines the relationship between prospective memory in executing a goal and various lapses of time from 20 minutes up to a 12- hour wake delay and a 12-hour sleep delay. The results suggest that consolidation processes active during sleep increase the probability of goal execution. The paper, titled 'Remembering to Execute a Goal: Sleep On It!' was published in Psychological Science in 2010 and was the basis for Michael K. Scullin's selection as the recipient of the 2011 Psi Chi/APA Edwin B. Newman Graduate Research Award. Mark A. McDaniel, PhD, served as faculty research advisor." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

Assessment of lipid profile of a group of undergraduates in Michael ...

African Journals Online (AJOL)

Objective: The aim of this study was to measure the lipid fractions in serum blood samples of apparently healthy undergraduates of Michael Okpara University of Agriculture, Umudike. Methods: A total of one hundred consenting males and females aged between 19-30 years were purposively selected from the ...

A celebration of mechanics: from nano to macro. The J. Michael T. Thompson Festschrift issue.

Science.gov (United States)

Elishakoff, Isaac

2013-06-28

This Theme Issue is dedicated to the topic 'Mechanics: from nano to macro' and marks the 75th birthday of Dr J. Michael T. Thompson, Fellow of the Royal Society, whose current affiliations are as follows: (i) Honorary Fellow, Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge; (ii) Emeritus Professor of Nonlinear Dynamics, Department of Civil, Environmental and Geomatic Engineering, University College London; and (iii) Professor of Theoretical and Applied Dynamics (Distinguished Sixth Century Chair, part-time), University of Aberdeen. He also serves as Chairman of the Board of Directors at ES-Consult (consulting engineers) in Copenhagen, Denmark. The pertinent question that arises from the very start is: should we first salute Michael and then describe the Theme Issue, or vice versa? Indeed, according to Blaise Pascal (1623-1662), the last thing one discovers in composing a work is what to put first. I would like to take the liberty of deviating from the tradition of the Philosophical Transactions and start with the tribute to Michael; after all he is the prime cause of this Theme Issue.

An Integrated Assessment of Progress in Robotic Perception and Semantic Navigation

Science.gov (United States)

2015-09-01

Navigation by Craig Lennon, Barry Bodt, Marshal Childers, Jean Oh, Arne Suppe, Luis Navarro-Serment, Robert Dean, Terrence Keegan , Chip Diberardino...Directorate, ARL Jean Oh, Arne Suppe, and Luis Navarro-Serment National Robotics Engineering Center, Pittsburgh, PA Robert Dean, Terrence Keegan ...AUTHOR(S) Craig Lennon, Barry Bodt, Marshal Childers, Jean Oh, Arne Suppe, Luis Navarro-Serment, Robert Dean, Terrence Keegan , Chip Diberardino

Euroopa parimaks filmiks sai Michael Haneke "Valge lint" / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2009-01-01

Euroopa Filmiakadeemia auhindadest: parima filmiauhinna sai Saksamaal Bochumis toimunud tseremoonial Michael Haneke "Valge lint", mille eest Haneke sai ka parima režissööri ja stsenaristi auhinna. Parimaks meesnäitlejaks pärjati Tahar Rahim ("Un Prophete"), parimaks naisnäitlejaks Kate Winslet ("The Reader"), publikupreemia sai Danny Boyle'i "Rentslimiljonär. Ka teistest võitjatest

C. P. Snow's "The Two Cultures": Michael Polanyi's Response and Context

Science.gov (United States)

Jacobs, Struan

2011-01-01

C. P. Snow's "The Two Cultures" controversially contrasted science and literature, suggesting that neither scientists nor literary intellectuals have much in common with, and seldom bother speaking to, the other. Responding to Snow, Michael Polanyi argued that specialization has made modern culture, not twofold but manifold. In his major work,…

Hydrogeochemical and stream sediment reconnaissance basic data for St. Michael Quadrangle, Alaska

International Nuclear Information System (INIS)

1981-01-01

Field and laboratory data are presented for 159 water samples from the St. Michael Quadrangle, Alaska. The samples were collected by Los Alamos National Laboratory; laboratory analysis and data reporting were performed by the Uranium Resource Evaluation Project at Oak Ridge, Tennessee

Astronaut C. Michael Foale is briefed on use of Sky Genie

Science.gov (United States)

1994-01-01

Astronaut C. Michael Foale, STS-63 mission specialist, is briefed on the use of Sky Genie device by Karin L. Porter. The device would aid in emergency egress operations aboard a troubled Space Shuttle. Porter, an employee of Rockwell International, helps train astronauts in egress procedures at JSC's Shuttle mockup and integration laboratory.

Little Mosie from the Margaree: A Biography of Moses Michael Coady.

Science.gov (United States)

Welton, Michael R.

This book examines the life of the Reverend Moses Michael Coady (1890-1959), a Roman Catholic priest who led the Antigonish Movement. During the Antigonish Movement, residents of the small maritime town of Antigonish, Nova Scotia, worked to achieve a nonviolent alternative to communism and fascism and to effect the social and economic…

Creative Industries, Value Theory and Michael Heinrich’s New Reading of Marx

Directory of Open Access Journals (Sweden)

Frederick H. Pitts

2015-06-01

Full Text Available This article utilises the new reading of Marx found in the work of Michael Heinrich to analyse the creative industries. It considers the role played in the production of value by the labour that takes place in the sphere of circulation. The specific focus is on creative industries such as graphic design, advertising and branding. It applies Heinrich's conceptualisation of 'social validation' to these sectors. This suggests that valorisation depends upon goods and services attaining commodity status by selling for money. Value is subject to this validation. The capitalist use of advertising, graphic design and branding guarantees the possibility of this validation. Using Heinrich, it reevaluates claims made about the creative industries and cognate fields in three main respects. First, it exposes as inadequate certain Marxist understandings of productive and unproductive labour and the place of circulation activities within this distinction. Second, it refutes autonomist Marxist claims as to the immeasurability of immaterial labour and the redundancy of the law of value. Third, it suggests that creative industries possess a significant role in a capitalist economy blighted by a necessity towards the overproduction of commodities.

Moral Education and Education in Altruism: Two Replies to Michael Hand

Science.gov (United States)

White, John

2016-01-01

This article is a critical discussion of two recent papers by Michael Hand on moral education. The first is his "Towards a Theory of Moral Education", published in the "Journal of Philosophy of Education" in 2014 (Volume 48, Issue 4). The second is a chapter called "Beyond Moral Education?" in an edited book of new…

A Critical Analysis of Michael Tippett's "A Child of Our Time"

Science.gov (United States)

Vallee, Jean-Sebastien

2009-01-01

After more than ten years of thoughtful planning, Michael Tippett (1905-1998) summed up his musical, political, spiritual and philosophical beliefs in his first oratorio, "A Child of Our Time" (1941). Representing the emergence of a new level of confidence and musical maturity for Tippett, the oratorio has become the composer's most widely known…

Gulliver's Travels: Michael Moore the Explorer in "Who to Invade Next"

Science.gov (United States)

Beck, Bernard

2016-01-01

America is identified as a nation of immigrants. These immigrants are thought to be the source of its subcultures. It is also a nation of individual explorers and inventors. Their activities are also a source of diverse subcultures. Many notable movies have made heroes of such innovators in different fields of endeavor. Michael Moore's movie…

An Interview with Michael Horn: Blending Education for High-Octane Motivation

Science.gov (United States)

Patterson, Gregory A.

2012-01-01

Blended learning holds the potential of improving the way we educate students and of making them more motivated. Blended education--the melding of information technology based distance learning with school attendance--is perhaps the best way to educate students for 21st century skills, says Michael Horn in a "Kappan" interview. Horn points out…

Tandem Michael addition/radical cyclizations for the construction of highly functionalized cyclopentanes

Czech Academy of Sciences Publication Activity Database

Holan, Martin; Pohl, Radek; Císarová, I.; Jahn, Ullrich

2012-01-01

Roč. 106, - (2012), s1298-s1298 ISSN 0009-2770. [EuCheMS Chemistry Congress /4./. 26.08.2012-30.08.2012, Prague] Institutional research plan: CEZ:AV0Z40550506 Keywords : cyclization * diastereoselectivity * Michael addiction * radical reactions * domino reactions Subject RIV: CC - Organic Chemistry

Highly Functionalized Cyclopentane Derivatives by Tandem Michael Addition/Radical Cyclization/Oxygenation Reactions

Czech Academy of Sciences Publication Activity Database

Holan, Martin; Pohl, Radek; Císařová, I.; Klepetářová, Blanka; Jones, P. G.; Jahn, Ullrich

2015-01-01

Roč. 21, č. 27 (2015), s. 9877-9888 ISSN 0947-6539 R&D Projects: GA ČR GA13-40188S Institutional support: RVO:61388963 Keywords : cyclization * domino reactions * electron transfer * Michael addition * radical reactions Subject RIV: CC - Organic Chemistry Impact factor: 5.771, year: 2015

An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions

Czech Academy of Sciences Publication Activity Database

Baszczyňski, Ondřej; Jansa, Petr; Dračínský, Martin; Kaiser, Martin Maxmilian; Špaček, Petr; Janeba, Zlatko

2012-01-01

Roč. 2, č. 4 (2012), s. 1282-1284 ISSN 2046-2069 R&D Projects: GA MV VG20102015046 Institutional research plan: CEZ:AV0Z40550506 Keywords : oxa-Michael addition * secondary alcohols * diethyl vinylphosphonate Subject RIV: CC - Organic Chemistry Impact factor: 2.562, year: 2012

Q & A with Ed Tech Leaders: Interview with Michael W. Allen

Science.gov (United States)

Shaughnessy, Michael F.

2014-01-01

Michael W. Allen, the Chairman and CEO of Allen Interactions, is an architect of interactive multimedia learning and is recognized for his many insights, inventions, and presentations. With over 50 years of experience in e-learning, both in academic and corporate settings, he is known for his role in creating Authorware and overseeing the work of…

Michael Polanyi and his generation origins of the social construction of science

CERN Document Server

Nye, Mary Jo

2011-01-01

In Michael Polanyi and His Generation, Mary Jo Nye investigates the role that Michael Polanyi and several of his contemporaries played in the emergence of the social turn in the philosophy of science. This turn involved seeing science as a socially based enterprise that does not rely on empiricism and reason alone but on social communities, behavioral norms, and personal commitments. Nye argues that the roots of the social turn are to be found in the scientific culture and political events of Europe in the 1930s, when scientific intellectuals struggled to defend the universal status of scientific knowledge and to justify public support for science in an era of economic catastrophe, Stalinism and Fascism, and increased demands for applications of science to industry and social welfare. At the center of this struggle was Polanyi, who Nye contends was one of the first advocates of this new conception of science. Nye reconstructs Polanyi’s scientific and political milieus in Budapest, Berlin, and Manchester f...

Book Review: America’s Blind Spot: Chávez, Oil and US Security by Andrés Cala and Michael Economides

DEFF Research Database (Denmark)

Boscan, Luis

2014-01-01

Review of: America’s Blind Spot: Chávez, Oil and US Security. Andrés Cala and Michael Economides. Continuum Books. 2012.......Review of: America’s Blind Spot: Chávez, Oil and US Security. Andrés Cala and Michael Economides. Continuum Books. 2012....

Enantio- and Stereoselective Construction of Atisane Scaffold via Organocatalytic Intramolecular Michael Reaction and Diels-Alder Reaction.

Science.gov (United States)

Sekita, Hiroko; Adachi, Kyohei; Kobayashi, Ippei; Sato, Yusuke; Nakada, Masahisa

2017-05-05

An enantio- and stereoselective construction of the atisane scaffold via organocatalytic intramolecular Michael reaction and Diels-Alder reaction is described. The organocatalytic intramolecular Michael reaction has been found to stereoselectively generate a trans-stereodiad comprising an all-carbon quaternary and a tertiary stereogenic centers. Use of the chiral secondary amine bearing thiourea with benzoic acid as additive is the key to obtaining the desired product with excellent ee in synthetically acceptable yield. The prepared chiral building block has been successfully converted to the compound including the atisane scaffold via the highly stereoselective intramolecular Diels-Alder reaction.

A Greener, Efficient Approach to Michael Addition of Barbituric Acid to Nitroalkene in Aqueous Diethylamine Medium

Directory of Open Access Journals (Sweden)

Hany J. Al-Najjar

2014-01-01

Full Text Available An efficient method for the synthesis of a variety of pyrimidine derivatives 3a–t by reaction of barbituric acids 1a,b as Michael donor with nitroalkenes 2a–k as Michael acceptor using an aqueous medium and diethylamine is described. This 1,4-addition strategy offers several advantages, such as using an economic and environmentally benign reaction media, high yields, versatility, and shorter reaction times. The synthesized compounds were identified by 1H-NMR, 13C-NMR, CHN, IR, and MS. The structure of compound 3a was further confirmed by single crystal X-ray structure determination.

Theory and practice in action: the contributions of Michael Perkins to clinical linguistics.

Science.gov (United States)

Damico, Jack S; Lynch, Karen E

2013-01-01

This article reviews the scholarly contributions of Michael R. Perkins in the discipline of clinical linguistics and provides some indication of the reasons that he has been so successful. Three primary attributes were described through an analysis of his publications.

Organocatalytic asymmetric michael addition of aldehydes to beta-nitroacroleine dimethyl acetal.

Science.gov (United States)

Reyes, Efraim; Vicario, Jose L; Badía, Dolores; Carrillo, Luisa

2006-12-21

[Structure: see text] The organocatalytic asymmetric Michael addition of aldehydes to beta-nitroacroleine dimethyl acetal has been studied in detail. The reaction took place with excellent yields and high stereoselectivities when a chiral beta-amino alcohol such as L-prolinol was employed as the catalyst, leaving a formation of highly functionalized enantioenriched compounds containing two differentiated formyl groups together with a nitro moiety.

Learned Helplessness Encountered by Michael Oher in the Blind Side Movie

OpenAIRE

PAMUNGKAS, DIMAS PROBO

2014-01-01

Pamungkas, Dimas Probo. 2014. Learned Helplessness Encountered by Michael Oher in The Blind Side Movie. Study Program of English, Department of Languages and Literature, Faculty of Culture Studies, Universitas Brawijaya. Supervisor: Dyah Eko Hapsari;Co-supervisor: Sarlettina Vidyayani EkaKeywords: Learned Helplessness, African-American, Psychological, Social Behavior, Depression, The Blind Side.Social behavior shows several interactions between person and social situations, which stress...

From Gouldner to Gramsci: The Making of Michael Apple's "Ideology and Curriculum"

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Gottesman, Isaac

2012-01-01

Michael Apple's "Ideology and Curriculum", published in 1979, helped initiate a broad turn in the field of education in the United States to Marxist thought as a lens through which to analyze the relationship between school and society. This classic text continues to inform scholarship in the field. While "Ideology" has…

Navigating Transition: Freedom, Limitation and the Post-colonial Persona in Michael Ondaatje's The Cat's Table

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Alaa Alghamdi

2012-11-01

Full Text Available Michael Ondaatje's 2011 novel The Cat's Table follows a young boy's voyage from Colombo, Sri Lanka to London, England. Through this character and the unique environment of the ship, which forms a compelling sense of transitory place, Ondaatje explores liminality and its relationship with limitations or barriers. The young protagonist, Michael, and his companions enjoy an unusual level of freedom aboard the contained and hierarchically segmented ship. Polarization and transition between Eastern and Western culture is present but pales in importance compared to the validation of the self that is located within and defined by the sense of the in-between, an essential rite of passage undertaken before re-joining society.

Isoindolinones as Michael Donors under Phase Transfer Catalysis: Enantioselective Synthesis of Phthalimidines Containing a Tetrasubstituted Carbon Stereocenter

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Francesco Scorzelli

2015-05-01

Full Text Available Readily available chiral ammonium salts derived from cinchona alkaloids have proven to be effective phase transfer catalysts in the asymmetric Michael reaction of 3-substituted isoindolinones. This protocol provides a convenient method for the construction of valuable asymmetric 3,3-disubstituted isoindolinones in high yields and  moderate to good enantioselectivity. Diastereoselectivity was also investigated in the construction of contiguous tertiary and quaternary stereocenters. The use of acrolein as Michael acceptor led to an interesting tricyclic derivative, a pyrroloisoindolinone analogue, via a tandem conjugated addition/cyclization reaction.

SYNTHESIS OF SOME PROLINE DERIVATIVES BY MEANS OF MICHAEL ADDITIONS OF GLYCINE ESTERS

NARCIS (Netherlands)

VANDERWERF, A; KELLOGG, RM

1991-01-01

Addition of the Schiff bases derived from reaction of glycine alkyl esters with benzophenoneimine to alpha,beta-unsaturated ketones, followed by hydrogenation of the addition products, leads to 5- or 3,5-substituted prolines. Hydrolysis of the Michael adducts rather than hydrogenation allows

Tõsine fotoelamus Dubrovnikus / Wade Goddard, Heidi Levine, Michael Robinson Chaver ; interv. Ahto Külvet

Index Scriptorium Estoniae

Goddard, Wade

2007-01-01

Dubrovniku vanalinnas asub Sõjafotokeskus. Intervjuu keskuse asutaja, kanadalasest fotograafi Wade Goddardi ja kahe seal augustis avatud näitusel osalenud fotograafi Heidi Levine'i ja Michael Robinson Chavez'iga. Sõjafotograafi tööst

Production of Low-Freezing-Point Highly Branched Alkanes through Michael Addition.

Science.gov (United States)

Jing, Yaxuan; Xia, Qineng; Liu, Xiaohui; Wang, Yanqin

2017-12-22

A new approach for the production of low-freezing-point, high-quality fuels from lignocellulose-derived molecules was developed with Michael addition as the key step. Among the investigated catalysts, CoCl 2 ⋅6 H 2 O was found most active for the Michael addition of 2,4-pentanedione with FA (single aldol adduct of furfural and acetone, 4-(2-furanyl)-3-butene-2-one). Over CoCl 2 ⋅6 H 2 O, a high carbon yield of C 13 oxygenates (about 75 %) can be achieved under mild conditions (353 K, 20 h). After hydrodeoxygenation, low-freezing-point (hydrodeoxygenation, high density (0.8415 g mL -1 ) and low-freezing-point (<223 K) branched alkanes with 18, 23 carbons within lubricant range were also obtained over a Pd/NbOPO 4 catalyst. These highly branched alkanes can be directly used as transportation fuels or additives. This work opens a new strategy for the synthesis of highly branched alkanes with low freezing point from renewable biomass. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

The Correspondence of Michael Faraday Pt 6 1860-1867

CERN Document Server

Frank, James

2012-01-01

Michael Faraday (1791-1867) was one of the most important men of science in nineteenth century Britain. His discoveries of electro-magnetic rotations (1821) and electro-magnetic induction (1831) laid the foundations of the modern electrical industry. His discovery of the magneto-optical effect and diamagnetism (1845) led him to formulate the field theory of electro-magnetism, which forms one of the cornerstones of modern physics.These and a whole host of other fundamental discoveries in physics and chemistry, together with his lecturing at the Royal Institution, his work for the state (includi

Kunstlik viljastamine - kas rahva püsimajäämise võti? / Michael Cook

Index Scriptorium Estoniae

Cook, Michael

2007-01-01

Kunstlikust viljastamisest pole üksi abi - vaid siis, kui noored mehed ja naised pööravad selja tarbimiskultusele ja individualismile, hakkab sündimus tõusma taastootmisest kõrgemale, kirjutab BioEdge toimetaja Michael Cook

Eesti disain on kõva, ent see tuleb moondada ekspordiks / Michael Thomson ; interv. Urmas Oja

Index Scriptorium Estoniae

Thomson, Michael

2008-01-01

Euroopa Disainiassotsiatsioonide Liidu presidendi ja Tallinnas toimunud festivali Disainiöö Eesti disainiauhinna Bruno žürii juhi Michael Thomsoni arvamus eesti disainist ning disainipoliitika vajalikkusest Eestis. Auhinnasaajate nimekiri

Compassionate leadership? Some reflections on the work and life of Michael Lapsley

Directory of Open Access Journals (Sweden)

Ian A. Nell

2016-03-01

Full Text Available In June 2007, I had the privilege of attending a Healing of Memories workshop lead by Father Michael Lapsley, one of the founder members of the Institute for Healing of Memories. The purpose of the workshop was to help the predominantly white members of a middle class Dutch Reformed congregation in the Northern Suburbs of Cape Town and the predominantly coloured members of a congregation of the Evangelical Lutheran Church in Elsies River on the Cape Flats, to share their stories of the past with regard to apartheid with each other. Apart from the stories that were told and the sharing of experiences about the apartheid history that took place, I was struck by the way in which Father Lapsley conducted the workshop. There was a deep compassion for all the participants as was embodied through the way in which he treated each of us with respect. But apart from his cordiality in leading the workshop, one could sense a deeper source of compassion, a source revealing a compassionate understanding of God�s presence amidst the violence and turmoil in our broken world. The aim of this article is to reflect on whether one could speak of something like �compassionate leadership�, and to take a closer look at the relationship between compassion and God images in the life and work of Michael Lapsley. Special attention will be given to the way in which he exercises leadership through his many involvements related to his own personal story of trauma.Intradisciplinary and/or interdisciplinary implications: This article presents literary research on the notion of compassionate leadership as a specific kind of leadership. The results indicate that the leadership of Father Michael Lapsley does indeed portray features of this kind of leadership. The research can become the source for finding new strategies for religious leadership.

Design and competitive edge: A model for design management excellence in European SME's

OpenAIRE

Borja de Mozota, B

2002-01-01

This article suggests to use the conceptual model of Michael Porter Value Chain in order to integrate all the variables that explain the mechanism of value creation through design. The results of the study of 33 European SMES participating in the European Design Prize explain the role of design in the management of innovation, identify the variables that characterize design management and classify them according to the value chain concept. The main result of this research was the ...

Interviews with Michael Baxandall, February 3rd and 4th, 1994, Berkeley, CA

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Allan Langdale

2009-12-01

Full Text Available The following interviews with Michael Baxandall were conducted in Berkeley on February 3rd and 4th of 1994. The content of these interviews include general responses about developments in art history in the years between 1960 and 1985, a period of dramatic modifications in the discipline. Among the issues are the rise of the social history of art and the sources from anthropology that informed Baxandall’s concept of the ‘Period Eye’. Baxandall talks about his own work, his personal intellectual history, and the scholars of past and current generations who influenced him. Other topics include Baxandall’s professional trajectory, the Warburg Library, and aspects of cultural history having to do with Renaissance Humanism. These interviews first appeared as an appendix to the PhD dissertation by Allan Langdale, Art History and Intellectual History: Michael Baxandall’s Work between 1963 and 1985, U. C. Santa Barbara, 1995.

Michael Maier--nine newly discovered letters.

Science.gov (United States)

Lenke, Nils; Roudet, Nicolas; Tilton, Hereward

2014-02-01

The authors provide a transcription, translation, and evaluation of nine newly discovered letters from the alchemist Michael Maier (1568-1622) to Gebhardt Johann von Alvensleben (1576-1631), a noble landholder in the vicinity of Magdeburg. Stemming from the final year of his life, this correspondence casts new light on Maier's biography, detailing his efforts to secure patronage amid the financial crisis of the early Thirty Years' War. While his ill-fated quest to perfect potable gold continued to form the central focus of his patronage suits, Maier also offered his services in several arts that he had condemned in his printed works, namely astrology and "supernatural" magic. Remarks concerning his previously unknown acquaintance with Heinrich Khunrath call for a re-evaluation of Maier's negotiation of the discursive boundaries between Lutheran orthodoxy and Paracelsianism. The letters also reveal Maier's substantial contribution to a work previously ascribed solely to the English alchemist Francis Anthony.

Political Cinema and Culture industry: the work of Michael Moore

OpenAIRE

Cristiane Toledo Maria

2015-01-01

This article aims to reflect upon the production of the American filmmaker Michael Moore, proposing as a central question the relationship established between art and politics in a historical moment which, on one side, points to the crisis of capitalism and, on the other side, to the political fragmentation of the working class. Focusing on the analysis of the documentaries Roger & Me (1989) and Capitalism: a love story (2009), this article is an attempt to understand the method developed by ...

Estratégia competitiva: Michael Porter 30 anos depois

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Manuel Portugal Ferreira

2009-12-01

Full Text Available Os estudos de estratégia têm sido muito influenciados pelos trabalhos de Michael Porter, em todas as suas fases, como as cinco forças, as estratégias genéricas, a cadeia de valor e as vantagens competitivas das nações. Neste artigo, analisou-se a influência de Porter nos trabalhos brasileiros em estratégia, a partir dos trabalhos selecionados e apresentados no EnANPAD. No levantamento para a análise dos artigos, considerando 10 anos de EnANPAD (1997-2006, foram selecionados 46 artigos. A identificação e seleção dos artigos envolveram os seguintes critérios: busca complementar por palavra-chave Porter na base de dados do EnANPAD; avaliação dos títulos e resumos dos artigos apresentados na área de estratégia entre 1997 e 2006, bem como na íntegra quando necessário. Procedeu-se também à análise das referências utilizadas nos artigos e o posicionamento dos autores em relação às tipologias de Porter. Como resultado, verificou-se que Michael Porter é um autor com grande influência nas pesquisas acadêmicas de estratégia. Seus estudos mais utilizados são os da análise da indústria e das estratégias genéricas, e também se verificou que a maioria dos estudos analisados é favorável aos seus conceitos, mesmo existindo pesquisas contrárias.

Noted astrophysicist Michael S. Turner to Head NSF'S mathematical and physical sciences directorate

CERN Multimedia

2003-01-01

"The National Science Foundation has named celebrated astrophysicist Michael S. Turner of the University of Chicago as Assistant Director for Mathematical and Physical Sciences. He will head a $1 billion directorate that supports research in mathematics, physics, chemistry, materials and astronomy, as well as multidisciplinary programs and education" (1/2 page).

Hexafluorobenzene: A powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reaction

KAUST Repository

Lattanzi, Alessandra

2012-01-01

A dramatic enhancement of the diastereo- and enantioselectivity in the nitro-Michael addition reaction organocatalysed by a commercially available α,α-l-diaryl prolinol was disclosed when performing the reaction in unconventional hexafluorobenzene as a medium. DFT calculations were performed to clarify the origin of stereoselectivity and the role of C 6F 6. © The Royal Society of Chemistry 2012.

Feeding Health: Michael Pollan on Improving Public Health through the Food Systems

Centers for Disease Control (CDC) Podcasts

2009-08-19

In this podcast, author Michael Pollan discusses his March 2009 visit to CDC and offers his thoughts on the intersection between the government, the food systems, and public health.  Created: 8/19/2009 by National Center for Environmental Health (NCEH), National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Office of Sustainability.   Date Released: 4/15/2010.

“This fabulous flotsam”: Michael Moorcock’s Urban Anthropology in “London under London”

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Houswitschka Christoph

2015-07-01

Full Text Available Michael Moorcock is often described as “one of the most prolific and varied writers working in Britain” (Malcolm 146. His success as a writer and editor of science fiction and fantasy literature is well established, but he is also the author of two novels about London, Mother London (1988 and King of the City (2000. Hardly known, Mother London by Michael Moorcock, offers itself to a variety of approaches that have been widely discussed in the context of studies on English literature during the Thatcher years, post-modernism, and psycho-geography. The novel resonates with the author’s own childhood in war-time London without being autobiographical. It tells the story of three Londoners who were traumatised during the Blitz. The following article focuses on the mysteries of subterranean London that represents the hidden and unconscious identities of its inhabitants in the post-war period.

Michael Marinov memorial volume multiple facets of quantization and supersymmetry

CERN Document Server

Vainshtein, A I

2002-01-01

This book is dedicated to the memory of Michael Marinov, the theorist who, together with Felix Berezin, introduced the classical description of spin by anticommuting Grassmann variables. It contains original papers and reviews by physicists and mathematicians written specifically for the book. These articles reflect the current status and recent developments in the areas of Marinov's research: quantum tunneling, quantization of constrained systems, supersymmetry, and others. The personal recollections included portray the human face of M Marinov, a person of great knowledge and integrity.

Subjectivity and Cultural Adjustment in Mathematics Education: A Response to Wolff-Michael Roth

Science.gov (United States)

Brown, Tony

2012-01-01

In this volume, Wolff-Michael Roth provides a critical but partial reading of Tony Brown's book "Mathematics Education and Subjectivity". The reading contrasts Brown's approach with Roth's own conception of subjectivity as derived from the work of Vygotsky, in which Roth aims to "reunite" psychology and sociology. Brown's book, however, focuses on…

What Work Do the Concepts of "Language" and "Literature" Do for Michael Rosenak?

Science.gov (United States)

Levisohn, Jon A.

2014-01-01

Michael Rosenak uses the twin metaphors of "language" and "literature," borrowed from Oakeshott and Peters, to argue that the goal of education is initiation into a language. This goal transcends the study of literature in that language. It includes, as well, the development of the capacity both to critique literature and to…

Briti ekspert : euroliidus kaob Eestist tööpuudus / Michael Richardson ; interv. Airi Ilisson

Index Scriptorium Estoniae

Richardson, Michael

2003-01-01

Eestis Suurbritannia tööreformi tutvustava töö- ja sotsiaalnõuniku sõnul on Suurbritannias peaaegu kadunud pikaajaline töötus noorte hulgas, vanematest inimestest on vaid üksikud tööta kauem kui aasta. Vt. samas: Kes on Michael Richardson?

Outside in America: George Michael's music video, public sex and global pop culture

NARCIS (Netherlands)

Kooijman, J.

2004-01-01

Six months after his controversial arrest for ‘lewd conduct’ at a men’s public restroom in Beverly Hills, British pop star George Michael released the song and music video ‘Outside’ which can be seen as an explicit commentary on the controversy. In this article, I read the music video in three ways:

[The problem of evil in families--the filmmaker Michael Haneke].

Science.gov (United States)

Skårderud, Finn

2010-09-23

With the beautiful and dark film "The white ribbon", from 2009, the Austrian film director Michael Haneke consolidated his status as an international success. A central theme in his films is evilness and its roots. But just as important is his ambition to develop films where evil is not only portrayed, but where spectators are challenged to relate to their own ethical standards and their role as spectators. Haneke is a highly original filmmaker with his consistent search for a film aesthetic that stimulates ethical self-reflection and mentalizing. He partly succeeds in this quest.

Adapting Shakespeare – Converting Shylock in Michael Radford’s the Merchant of Venice

Directory of Open Access Journals (Sweden)

Oakes Luke

2016-08-01

Full Text Available This article aims to explore the extension and evolution of Shakespeare’s The Merchant of Venice through Michael Radford’s 2004 cinematic adaptation. By investigating the concept of adaptation and the significance of intertextuality, Shakespeare’s source text is considered alongside Radford’s twenty-first century recreation to reimagine and redefine the construction of Shylock as both a comic and tragic device utilized across film and play. Issues of racial and religious prejudices alongside anti- Semitic views were particularly prominent in Elizabethan England and, by concentrating on recontextualisation, this article looks to expose Shakespeare’s characterization as a reflective commentary concerning societal discriminations at the time of the play’s performance. By focusing primarily on Shakespeare’s Jewish Usurer, Radford is able to reconstruct and reestablish the dramatic devices and characters within the cinematic version, metaphorically converting Shylock from comic villain to tragic victim. Finally, it argues that this dynamic shift inevitably metamorphoses Shylock from a spectator’s perspective and provides Michael Radford with an opportunity to offer a social commentary on social inequality in the twenty-first century.

Training and Mastery of Techniques in Wittgenstein's Later Philosophy: A Response to Michael Luntley

Science.gov (United States)

Stickney, Jeff

2008-01-01

Responding to Michael Luntley's article, "Learning, Empowerment and Judgement," the author shows he cannot successfully make the following three moves: (1) dissolve the analytic distinction between learning by training and learning by reasoning, while advocating the latter; (2) diminish the role of training in Wittgenstein's philosophy, nor…

European Management: an emerging competitive advantage of European nations : A reply to Michael Porter

NARCIS (Netherlands)

F.A.J. van den Bosch (Frans); A.A. van Prooijen

1992-01-01

textabstractThis article extends the debate begun in the June 1992 issue of EMJ when the authors first criticized Michael Porter's explanatory framework in his Competitive Advantage of Nations (1990), over the role of national culture on the competitive advantage of nations. In this paper, Frans van

Las relaciones entre la Iglesia y el Estado en la teoría de la justicia de Michael Walzer

OpenAIRE

Roldán, Alberto Fernando

2009-01-01

Roldan, A. F. (2009). Las relaciones entre la Iglesia y el Estado en la teoría de la justicia de Michael Walzer (Tesis de Maestría). Universidad Nacional de Quilmes, Bernal, Argentina. En la presente tesis, se discuten las relaciones entre la Iglesia –término que se utiliza no en el sentido confesional sino en tanto institución religiosa- y el Estado moderno. Se escoge como marco teórico la filosofía política del pensador judío americano Michael Walzer, exponente del “comunitarismo”, un...

The Educational Philosophies of Mordecai Kaplan and Michael Rosenak: Surprising Similarities and Illuminating Differences

Science.gov (United States)

Schein, Jeffrey; Caplan, Eric

2014-01-01

The thoughts of Mordecai Kaplan and Michael Rosenak present surprising commonalities as well as illuminating differences. Similarities include the perception that Judaism and Jewish education are in crisis, the belief that Jewish peoplehood must include commitment to meaningful content, the need for teachers to teach from a position of…

Obituary: Michael John Klein, 1940-2005

Science.gov (United States)

Gulkis, Samuel

2006-12-01

Michael John Klein died on 14 May 2005 at home in South Pasadena, California. The cause of death was tongue cancer that metastasized to the lungs. He was a non-smoker. Mike was a passionate radio astronomer, a trusted astronomical observer, an educator and a family man. Mike was born on 19 January 1940 in Ames, Iowa, the son of Florence Marie (Graf) and Fred Michael Klein. His mother was a homemaker, and his father was a banker. Mike had two older sisters, Lois Jean (Klein) Flauher and Marilyn June (Klein) Griffin. In 1962, Mike married his high school sweetheart Barbara Dahlberg, who survives him along with their three children, Kristin Marie (Klein) Shields, Michael John Klein Jr., Timothy Joel Klein, and six grandchildren. Mike developed a love for astronomy early in his life, and credited an early morning, newspaper-delivery route that he had at age twelve, which took him outside well before sunrise. He told family members that as he walked along his route, he stared into the sky and wondered what everything was. He studied sky charts, located stars, and began to understand how the planets shifted their positions relative to the stars each day. Another big influence in Mike's life was his brother in-law, Jim Griffin. Jim helped Mike understand that his passion for science did not have to remain a hobby, but could and should become a career. Jim's encouragement led Mike to attend Iowa State University in Ames, where he earned a BS in electrical engineering in 1962. Mike then started graduate school in electrical engineering at Michigan State, but after one semester transferred to the University of Michigan, Ann Arbor, where he earned an MS (1966) and PhD (1968) in astronomy. His doctoral dissertation, under the direction of Professor Fred Haddock, was based on extensive observations of the planets and examined the physical and thermal properties of planetary atmospheres and surfaces. Mike was awarded a Resident Research Associate position at JPL by the National

Wolff-Michael Roth's passibility: at the limits of the constructivist metaphor: a book review

Science.gov (United States)

Brendel, Michelle

2014-12-01

Wolff-Michael Roth deconstructs the preeminent role conceded to constructivism in Science Education and demonstrates how we learn and know through pain, suffering, love or passion. This review explores his book "Passibility: At the Limits of the Constructivist Metaphor" through the eyes of an outsider to the world of science education.

"Raising Standards" or Reducing Aspirations and Opportunities Still Further? Michael Gove and Examination Reforms

Science.gov (United States)

Allen, Martin

2013-01-01

Well before the examinations grade crisis of 2012, Michael Gove had set out clear intentions for reforming public examinations. Though he claimed to be improving examinations and assessment by replicating practices that took place in high-performing countries and thus improving the ability of the UK economy to "compete", this…

O que é a Multidão? Questões para Michael Hardt e Antonio Negri

Directory of Open Access Journals (Sweden)

Nicholas Brown

2006-07-01

Full Text Available Multidão, livro mais recente de Michael Hardt e Antonio Negri, é uma tentativa de nomear e compreender as condições que envolvem a dinâmica social do século xxi. Na entrevista a seguir, Hardt e Negri discorrem sobre as possibilidades de constituição da multidão como agente político, discutem os fundamentos do livro e defendem conceitos que consideram determinantes para a compreensão dos novos tempos, tais como biopolítica e biopoder.Multitude, Michael Hardt and Antonio Negri’s latest book, is an attempt at understanding conditions involving social dynamics in the xxi century. In the interview below, Hardt and Negri consider the constitution of the multitude as a political agent, discuss the structure of their book and support concepts seen as crucial for the comprehension of our time, such as biopolitics and biopower.

Correction: Synthesis of pyrrolidine-3-carboxylic acid derivatives via asymmetric Michael addition reactions of carboxylate-substituted enones.

Science.gov (United States)

Yin, Feng; Garifullina, Ainash; Tanaka, Fujie

2018-04-25

Correction for 'Synthesis of pyrrolidine-3-carboxylic acid derivatives via asymmetric Michael addition reactions of carboxylate-substituted enones' by Feng Yin et al., Org. Biomol. Chem., 2017, 15, 6089-6092.

Gender Relations and Sexual Harassment in the Workplace: Michael Crichton's "Disclosure" as a Teaching Tool.

Science.gov (United States)

Comer, Debra R.; Cooper, Elizabeth A.

1998-01-01

Describes how to use Michael Crichton's novel "Disclosure" and the film based on it for class discussions of such issues as what constitutes sexual harassment, harassment of men, relationship between sexual harassment and power, organizational responses to harassment, and gender differences in career advancement tactics. (SK)

Solvent-free, catalyst-free aza-Michael addition of cyclohexylamine to diethyl maleate: reaction mechanism and kinetics

Czech Academy of Sciences Publication Activity Database

Bláha, Michal; Trhlíková, Olga; Podešva, Jiří; Abbrent, Sabina; Steinhart, Miloš; Dybal, Jiří; Dušková-Smrčková, Miroslava

2018-01-01

Roč. 74, č. 1 (2018), s. 58-67 ISSN 0040-4020 Institutional support: RVO:61389013 Keywords : Aza-Michael addition * solvent-free * catalyst-free Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 2.651, year: 2016

LECTURE CANCELLED - “The power of collaboration - innovating collaborative relationships" by Michael Kimmel | 8 March

CERN Multimedia

2013-01-01

PLEASE NOTE THAT THIS LECTURE IS CANCELLED Friday, 8 March -  from 11.30 a.m. to 1 p.m. Globe of Science and Innovation Route de Meyrin, 1211 Geneva International Women’s Day Conference Lecture will be in English - Interpreting available in French Limited number of seats - registration is essential Reservation: + 41 22 767 76 76 or cern.reception@cern.ch Dr. Michael Kimmel, a renowned sociologist and an expert on male-female relationships, will share his latest findings on gender collaboration and how it can lead to innovation and improved relationships both at work and in the world outside. Michael Kimmel is among the world’s leading experts on male-female relationships. A Professor of Sociology at the State University of New York at Stony Brook, he is the author or editor of more than 20 books on the topic. He consults corporations, NGOs and public sector organisations all over the world on gender equity issues, including work-family balance, reducing workplac...

Dr Michaels® product family (also branded as Soratinex®) versus Methylprednisolone aceponate - a comparative study of the effectiveness for the treatment of plaque psoriasis.

Science.gov (United States)

Hercogovấ, J; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Tirant, M; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

2016-01-01

As one of the most common dermatologic chronic-recurrent disease, variable therapeutic options are available today for management of psoriasis. Although topical high potency corticosteroids, alone or in association with salicylic acid or vitamin D analogues, are still considered the best treatment, they do not seem to possess the capability for a long-term control of the disease or prevent recurrences, as their side effects are major contraindications for continuative use. The aim of this study was to investigate whether Dr. Michaels® product family is comparable to methylprednisolone aceponate (MPA) as a viable alternative treatment option for the treatment and management of stable chronic plaque psoriasis. Thirty adults (13 male, 17 female, mean age 40 years) with mild to severe stable chronic plaque psoriasis, were included in the study. Patients were advised to treat the lesions of the two sides of their body (left and right) with two different unknown modalities for 8 weeks; the pack of Dr. Michaels® products on the left side (consisting of a cleansing gel, an ointment and a skin conditioner) and a placebo pack on the right side, consisting of a cleansing gel, methylprednisolone ointment and a placebo conditioner. Assessment was done using the Psoriasis Activity Severity Index (PASI) scores before treatment and after 2, 4, 6 and 8 weeks. The results achieved with the Dr. Michaels® (Soratinex®) product family for the treatment of chronic plaque psoriasis were better than the results achieved with methylprednisolone aceponate (MPA), even though quicker resolution was achieved with the steroid with 45% of patients achieving resolution within 8-10 days in comparison to 5-6 weeks in the Dr. Michaels® (Soratinex®) group. Before therapy, the mean PASI score of the LHS in Dr. Michaels® (Soratinex®) group was 13.8±4.1 SD and 14.2±4.2 SD in the RHS methylprednisolone aceponate (MPA) group. After 8 weeks of treatment 62% of the Dr. Michaels® (Soratinex

Tandem Knoevenagel–Michael reactions in aqueous diethylamine medium: A greener and efficient approach toward bis-dimedone derivatives

Directory of Open Access Journals (Sweden)

Abdullah Mohammed Al-Majid

2017-02-01

The use of inexpensive, eco-friendly and readily available reagents, easy work-up, and high purity products makes the procedure a convenient and robust method for the synthesis of tandem Knoevenagel–Michael adducts.

An Interview with Michael Betancourt, author of Agnotology & Crisis in Digital Capitalism

OpenAIRE

Sean Scanlan; Michael Betancourt

2015-01-01

Sean Scanlan, NANO's editor, interviews artist, curator, art historian and critical theorist Michael Betancourt to discuss the nature of agnotology, a term that means the “creation of uncertainty and ambivalent ‘fact’; it is a competitive tool incompatible with the idealized ‘free market’ of capitalism.” Betancourt is skeptical of Big Data and the ways that the consumers who unknowingly “produce” data for business interpretation are increasingly becoming transformed into a “token of exchange ...

POLYETHYLENEIMINE (PEI ON SILICA AS CATALYST IN KNOEVENAGEL AND MICHAEL REACTIONS

Directory of Open Access Journals (Sweden)

FATIHA ZAOUI

2017-03-01

Full Text Available After the synthesis of polyethylenimine supported on silica, it has been used as a new and efficient catalyst in Knoevenagel and Michael condensations. The presence of the polyethylenimine in the catalytic system together with silica displays an acido-basic character allows a better catalytic activity in the condensations. Carried out under microwave irradiation, without organic solvent and during short time, the syntheses are respectful towards green chemistry. The solid catalyst can be easily reused. This catalyst has the acido-basic character at the same time.

Komparativistlikke ja kultuuriteaduslikke ärgitusi Baltimaade germanistikale / Michael Schwidtal ; saksa keelest tõlkinud Vahur Aabrams

Index Scriptorium Estoniae

Schwidtal, Michael

2001-01-01

3. - 5. sept. 2001 toimus Riias sümpoosion "Unter diesem braunen Himmel. Jakob Michael Reinhold Lenz und die deutsche Literatur des Baltikums", 7. - 9. sept. Tartus "Torm ja tung Liivimaal. Mässu mudelid", pühendatud J. M. R. Lenzi ja Kristian Jaak Petersoni loomingule. Ülevaade

N-Heterocyclic-Carbene-Catalysed Diastereoselective Vinylogous Mukaiyama/Michael Reaction of 2-(Trimethylsilyloxy)furan and Enones

KAUST Repository

Wang, Ying; Du, Guang Fen; Xing, Fen; Huang, Kuo-Wei; Dai, Bin; He, Lin

2015-01-01

N-heterocyclic carbenes have been utilised as highly efficient nucleophilic organocatalysts to mediate vinylogous Mukaiyama/Michael reactions of 2-(trimethylsilyloxy)furan with enones to afford γ-substituted butenolides in 44-99% yield with 3:1-32:1 diastereoselectivity. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

N-Heterocyclic-Carbene-Catalysed Diastereoselective Vinylogous Mukaiyama/Michael Reaction of 2-(Trimethylsilyloxy)furan and Enones

KAUST Repository

Wang, Ying

2015-10-15

N-heterocyclic carbenes have been utilised as highly efficient nucleophilic organocatalysts to mediate vinylogous Mukaiyama/Michael reactions of 2-(trimethylsilyloxy)furan with enones to afford γ-substituted butenolides in 44-99% yield with 3:1-32:1 diastereoselectivity. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Review: Barr, Michael and Zlatko Skrbiš (2008, Constructing Singapore. Elitism, Ethnicity and the Nation-Building Project

Directory of Open Access Journals (Sweden)

Boris Michel

2009-01-01

Full Text Available Review of the monograph: Barr, Michael and Zlatko Skrbiš, Constructing Singapore. Elitism, Ethnicity and the Nation-Building Project, Copenhagen: NIAS Press, 2008, ISBN 978-87-7694-029-4, 304 pages

New eco-friendly animal bone meal catalysts for preparation of chalcones and aza-Michael adducts

Directory of Open Access Journals (Sweden)

Riadi Yassine

2012-06-01

Full Text Available Abstract Two efficient reactions were successfully carried out using Animal Bone Meal (ABM and potassium fluoride or sodium nitrate doped ABMs as new heterogeneous catalysts under very mild conditions. After preparation and characterization of the catalysts, we first report their use in a simple and convenient synthesis of various chalcones by Claisen–Schmidt condensation and then in an aza-Michael addition involving several synthesized chalcones with aromatic amines. All the reactions were carried out at room temperature in methanol; the chalcone synthesis was also achieved in water environment under microwave irradiation. Doping ABM enhances the rate and yield at each reaction. Catalytic activities are discussed and the ability to re-use the ABM is demonstrated. Results For Claisen–Schmidt the use of ABM alone, yields never exceeded 17%. In each entry, KF/ABM and NaNO3/ABM (79-97% gave higher yields than using ABM alone under thermic condition. Also the reaction proceeded under microwave irradiation in good yields (72-94% for KF/ABM and 81-97% for NaNO3/ABM and high purity. For aza-Michael addition the use of ABM doped with KF or NaNO3 increased the catalytic activity remarkably. The very high yields could be noted (84-95% for KF/ABM and 81-94% for NaNO3/ABM. Conclusion The present method is an efficient and selective procedure for the synthesis of chalcones an aza-Michael adducts. The ABM and doped ABMs are a new, inexpensive and attractive solid supports which can contribute to the development of catalytic processes and reduced environmental problems.

Design dis-integration Silent, Partial, and Disparate Design

OpenAIRE

Stevens, John; Moultrie, James; Crilly, Nathan

2009-01-01

Michael Porter’s frameworks for analysing and planning competitive differentiation (Porter 1980, 1985) are established ‘textbook’ tools, widely taught to business students today. As the claim of design’s strategic importance is increasingly heard, we ask where does design fit in established strategy thinking? This paper documents a proposed conceptual model based on Porter’s value chain model for strategic planning. The concept outlined is the result of the first stage of a larger study of ...

Tagasipöördumine esteetika juurde = Return to aesthetics / Keith Moxey, Michael Ann Holly ; interv. Anu Allas

Index Scriptorium Estoniae

Moxey, Keith

2007-01-01

Ameerika kunstiajaloolased Keith Moxey ning Michael Ann Holly tutvustavad uut lähenemist kunstiajaloole (new art history). Nn. naasmine esteetika juurde tähendab püüet integreerida kunstiajalukku ja -teooriasse uuesti ja tugevamalt kunstiteos

The big picture : What the Baltics may learn from Ireland's success story / Michael Bourke ; interv. Maris Biezaitis

Index Scriptorium Estoniae

Bourke, Michael

2002-01-01

Ilmunud ka: Baltiiskii kurss 2002/Zima/Vesna nr. 20 lk. 14-17. Iirimaa aukonsul Lätis, Michael Joseph Bourke arutleb Iirimaa majandusedu teemal ning pakub välja, mida Baltimaad saaksid sellest õppida. Tabel, diagramm. Lisa

Horror movie aspects and experimentation in Michael Jackson’s Thriller music video

OpenAIRE

Vargas, Herom; Universidade Municipal de São Caetano do Sul - USCS; Gonçalves, Rafael; Universidade Municipal de São Caetano do Sul - USCS

2016-01-01

This article analyzes the use of elements from the horror fi lm genre in the music video Thriller (1982), by Michael Jackson, as experimentation within the field of pop music. Based on the semiotics of culture, grounded on the concepts of cultural text, semiosphere, border and modeling, developed by Iuri Lotman, the analysis identified innovations in the use of horror as humor and, in the music, modeling of creatures, moving among horror, the fantastic and the reality.Keywords: horror, music ...

Thomas DaCosta Kaufmann and Michael North (eds., Mediating Netherlandish Art and Material Culture in Asia

Directory of Open Access Journals (Sweden)

Claartje Rasterhoff

2015-12-01

Full Text Available Book notice of: Thomas DaCosta Kaufmann and Michael North (eds., Mediating Netherlandish Art and Material Culture in Asia (Amsterdam Studies in the Dutch Golden Age Amsterdam, Amsterdam University Press, 2014. 348 pp. ISBN 978-90-8964-569-2. € 99,00.

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations.

Science.gov (United States)

Aceña, José Luis; Sorochinsky, Alexander E; Soloshonok, Vadim

2014-09-01

The major goal of this review is a critical discussion of the literature data on asymmetric synthesis of α-amino acids via Michael addition reactions involving Ni(II)-complexes of amino acids. The material covered is divided into two conceptually different groups dealing with applications of: (a) Ni(II)-complexes of glycine as C-nucleophiles and (b) Ni(II)-complexes of dehydroalanine as Michael acceptors. The first group is significantly larger and consequently subdivided into four chapters based on the source of stereocontrolling element. Thus, a chiral auxiliary can be used as a part of nucleophilic glycine Ni(II) complex, Michael acceptor or both, leading to the conditions of matching vs. mismatching stereochemical preferences. The particular focus of the review is made on the practical aspects of the methodology under discussion and mechanistic considerations.

Michael Longley’s Father: Memory, Mourning and History

Directory of Open Access Journals (Sweden)

Barry Sloan

2012-03-01

Full Text Available Michael Longley’s father has been a recurring presence in the poet’s work from his earliest to his most recent collection. This paper examines the exceptional strength of that bond reflected in the varied and changing ways in which the poet has responded to it – memorizing and mourning his loss; discovering through his father’s First World War stories a means of memorialising loss of life in contemporary conflicts and a way of facing the history of the twentieth century; confronting his own ageing and sense of mortality; and marking the specific, but also representative, generational history of his family. Close readings of key poems are offered to highlight Longley’s skills in meeting his own exacting standards of aesthetic propriety and moral and social responsibility for writers of elegy in order to avoid either exploitation of tragedy and loss, or facile gestures of consolation.

Theoretical study on the reaction mechanisms of Michael chirality addition between propionaldehyde and nitroalkene catalyzed by an enantioselective catalyst.

Science.gov (United States)

Zhou, Xinming; Li, Ling; Sun, Xuejun; Wang, Yajun; Du, Dongmei; Fu, Hui

2018-06-01

The asymmetric Michael addition between propionaldehyde and nitroalkene catalyzed by 8-(ethoxycarbonyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid has obtained relatively high yields and excellent enantioselectivities at room temperature. In this study, the molecular structures and optical activity of the most stable conformation I are optimized at B3LYP/6-311++ G(d,p) level. We find that levorotatory conformation I catalyzing the same Michael addition can produce laevo-product A and dextrorotatory conformation I' can obtain the dextral-product A'. These results have guiding significance for further studying on the new chemzymes and the mechanism of the obtained different chiral products. © 2018 Wiley Periodicals, Inc.

Recollections of Jack Michael and the Application of Skinner's Analysis of Verbal Behavior

Science.gov (United States)

Sundberg, Mark L.

2017-01-01

Jack Michael offered a course on verbal behavior almost every year throughout his teaching career. Jack was also interested in the application of Skinner's work and in 1976 began to offer a graduate course at Western Michigan University titled Verbal Behavior Applications. Jack and his students pursued the application of Skinner's work on verbal…

Invited Commentary: Continuing to Loosen the Constraints on Epidemiology in an Age of Change-A Comment on McMichael's "Prisoners of the Proximate".

Science.gov (United States)

Galea, Sandro

2017-06-01

Published in 1999, McMichael's "Prisoners of the Proximate: Loosening the Constraints on Epidemiology in an Age of Change" (Am J Epidemiol. 1999;149(10):887-897) outlined an exciting vision for epidemiology as the field that that can help us better understand the drivers of population health so that we may intervene, paving the way for healthier populations. McMichael's paper remains today what it was when it was first published: clear, thoughtful, provocative, and usefully prescriptive in its call to action. McMichael identified 4 constraints facing epidemiology. The field has risen to this challenge and addressed some of these constraints. I discuss how successful (or not) we have been in addressing each of these 4 challenges. © The Author 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The works of Joseph and Michael Haydn in Ondřej Horník's collection

Czech Academy of Sciences Publication Activity Database

Freemanová, Michaela

2017-01-01

Roč. 9, 1-2 (2017), s. 14-23 ISSN 1803-7828 Institutional support: RVO:68378076 Keywords : music manuscripts * Joseph Haydn * Michael Haydn * Ondřej Horník's collection * church music Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Performing arts studies ( Music ology, Theater science, Dramaturgy) http://www.nm.cz/publikace/archiv.php?id=16

Progress in ultrasonic spray pyrolysis for condensed matter sciences developed from ultrasonic nebulization theories since Michael Faraday

CSIR Research Space (South Africa)

Mwakikunga, BW

2014-01-01

Full Text Available This review outlines, in great detail, the history of the phenomenon of ultrasonic nebulization of liquids since the discovery of such an effect by Michael Faraday and the explanation of the phenomenon by capillary wave mechanism and “cavitation...

A facile and efficient method of enzyme immobilization on silica particles via Michael acceptor film coatings: immobilized catalase in a plug flow reactor.

Science.gov (United States)

Bayramoglu, Gulay; Arica, M Yakup; Genc, Aysenur; Ozalp, V Cengiz; Ince, Ahmet; Bicak, Niyazi

2016-06-01

A novel method was developed for facile immobilization of enzymes on silica surfaces. Herein, we describe a single-step strategy for generating of reactive double bonds capable of Michael addition on the surfaces of silica particles. This method was based on reactive thin film generation on the surfaces by heating of impregnated self-curable polymer, alpha-morpholine substituted poly(vinyl methyl ketone) p(VMK). The generated double bonds were demonstrated to be an efficient way for rapid incorporation of enzymes via Michael addition. Catalase was used as model enzyme in order to test the effect of immobilization methodology by the reactive film surface through Michael addition reaction. Finally, a plug flow type immobilized enzyme reactor was employed to estimate decomposition rate of hydrogen peroxide. The highly stable enzyme reactor could operate continuously for 120 h at 30 °C with only a loss of about 36 % of its initial activity.

Enantioselective organocatalyzed Oxa-Michael-Aldol cascade reactions: Construction of chiral 4H-chromenes with a trifluoromethylated tetrasubstituted carbon stereocenter

KAUST Repository

Zhang, Jing; Ajitha, Manjaly John; He, Lin; Liu, Kai; Dai, Bin; Huang, Kuo-Wei

2015-01-01

The first organocatalytic asymmetric synthesis of 4H-chromenes bearing a trifluoromethylated tetrasubstituted carbon center is presented. Chiral secondary amines promote the oxa-Michael-aldol cascade reaction between alkynals and 2

Why There Are Certain Parallels Between Joachim C. Fest’s Hitler-Biography and Michael Wolff’s Trump-Book

Directory of Open Access Journals (Sweden)

Christian Fuchs

2018-02-01

Full Text Available Joachim C. Fest published one of the most widely read Hitler biographies in 1973. Are there parallels of its analytical approach to Michael Wolff’s “Fire and Fury: Inside the Trump White House”?

Michael T. Westrate. Living Soviet in Ukraine from Stalin to Maidan: Under the Falling Red Star in Kharkiv.

Directory of Open Access Journals (Sweden)

Charitie V. Hyman

2017-09-01

Full Text Available Book review of Michael T. Westrate. Living Soviet in Ukraine from Stalin to Maidan: Under the Falling Red Star in Kharkiv. Rowman & Littlefield, 2016. xx, 232 pp. Illustrations. Appendices. Bibliography. Index. $85.00, cloth.

Jack Michael's Musings on the 60th Anniversary of Skinner's "Verbal Behavior"

Science.gov (United States)

Esch, Barbara E.; Esch, John W.; Palmer, David C.

2017-01-01

When the B. F. Skinner Foundation reprinted Skinner's "Verbal Behavior" in 1992, Jack Michael wrote one of its two forewords, a detailed outline of the book's purpose and scope. On the 60th anniversary of the first publication (1957) of "Verbal Behavior", Jack reflects on the book's impact and its importance to the…

Asymmetric organocatalytic Michael addition of Meldrum's acid to nitroalkenes: probing the mechanism of bifunctional thiourea organocatalysts

OpenAIRE

Kataja, Antti O.; Koskinen, Ari M.P.

2010-01-01

The asymmetric Michael addition of Meldrum’s acid to nitroalkenes was studied using a novel type of Cinchona alkaloid-based bifunctional thiourea organocatalyst. The functionality of the thiourea catalysts was also probed by preparing and testing thiourea-N-methylated analogues of the well-known bis-(3,5-trifluoromethyl)phenyl-substituted catalyst. Peer reviewed

Vision and Elusiveness in Philosophy of Education: R. S. Peters on the Legacy of Michael Oakeshott

Science.gov (United States)

Williams, Kevin

2009-01-01

Despite his elusiveness on important issues, there is much in Michael Oakeshott's educational vision that Richard Peters quite rightly wishes to endorse. The main aim of this essay is, however, to consider Peters' justifiable critique of three features of Oakeshott's work. These are (1) the rigidity of his distinction between vocational and…

Hexamethoxylated Monocarbonyl Analogues of Curcumin Cause G2/M Cell Cycle Arrest in NCI-H460 Cells via Michael Acceptor-Dependent Redox Intervention.

Science.gov (United States)

Li, Yan; Zhang, Li-Ping; Dai, Fang; Yan, Wen-Jing; Wang, Hai-Bo; Tu, Zhi-Shan; Zhou, Bo

2015-09-09

Curcumin, derived from the dietary spice turmeric, holds promise for cancer prevention. This prompts much interest in investigating the action mechanisms of curcumin and its analogues. Two symmetrical hexamethoxy-diarylpentadienones (1 and 2) as cucumin analogues were reported to possess significantly enhanced cytotoxicity compared with the parent molecule. However, the detailed mechanisms remain unclear. In this study, compounds 1 and 2 were identified as the G2/M cell cycle arrest agents to mediate the cytotoxicity toward NCI-H460 cells via Michael acceptor-dependent redox intervention. Compared with curcumin, they could more easily induce a burst of reactive oxygen species (ROS) and collapse of the redox buffering system. One possible reason is that they could more effectively target intracellular TrxR to convert this antioxidant enzyme into a ROS promoter. Additionally, they caused up-regulation of p53 and p21 and down-regulation of redox-sensitive Cdc25C along with cyclin B1/Cdk1 in a Michael acceptor- and ROS-dependent fashion. Interestingly, in comparison with compound 2, compound 1 displayed a relatively weak ability to generate ROS but increased cell cycle arrest activity and cytotoxicity probably due to its Michael acceptor-dependent microtubule-destabilizing effect and greater GST-inhibitory activity, as well as its enhanced cellular uptake. This work provides useful information for understanding Michael acceptor-dependent and redox-mediated cytotoxic mechanisms of curcumin and its active analogues.

Optical Interference Coatings Design Contest 2013: angle-independent color mirror and shortwave infrared/midwave infrared dichroic beam splitter.

Science.gov (United States)

Hendrix, Karen; Kruschwitz, Jennifer D T; Keck, Jason

2014-02-01

An angle-independent color mirror and an infrared dichroic beam splitter were the subjects of a design contest held in conjunction with the 2013 Optical Interference Coatings topical meeting of the Optical Society of America. A total of 17 designers submitted 63 designs, 22 for Problem A and 41 for Problem B. The submissions were created through a wide spectrum of design approaches and optimization strategies. Michael Trubetskov and Weidong Shen won the first contest by submitting color mirror designs with a zero color difference (ΔE00) between normal incidence and all other incidence angles up to 60° as well as the thinnest design. Michael Trubetskov also won the second contest by submitting beam-splitter designs that met the required transmission while having the lowest mechanical coating stress and thinnest design. Fabien Lemarchand received the second-place finish for the beam-splitter design. The submitted designs are described and evaluated.

Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

Science.gov (United States)

Xie, Zong-Bo; Wu, Ming-Yu; He, Ting; Le, Zhang-Gao

2012-01-01

Summary An environmentally benign, fast and convenient protocol has been developed for the Michael addition of 1,3-dicarbonyl compounds to β-nitroalkenes in good to excellent yields by a grinding method under catalyst- and solvent-free conditions. PMID:22563352

A Revised Interface for the ARL Topodef Mobility Design Tool

Science.gov (United States)

2012-04-01

designed paths as though moving down a conveyor belt . Giving paths an existence independent of the nodes that travel along them not only makes their...A Revised Interface for the ARL Topodef Mobility Design Tool by Andrew J. Toth and Michael Christensen ARL-TR-5980 April 2012...Disclaimers The findings in this report are not to be construed as an official Department of the Army position unless so designated by other

Organocatalytic Michael and Friedel–Crafts reactions in enantioselective synthesis of biologically active compounds

International Nuclear Information System (INIS)

Maltsev, O V; Beletskaya, Irina P; Zlotin, Sergei G

2011-01-01

Recent applications of organocatalytic Michael and Friedel–Crafts reactions in enantioselective synthesis of biologically active compounds: natural products, pharmaceutical agents and plant protection agents are reviewed. The key mechanisms of stereoinduction, types of organocatalysts and reagents used in these reactions are considered. The material is classified according to the type of newly formed bonds incorporating the asymmetric carbon atom, and the information for the most numerous C–C coupling reactions is systematized according to the natures of the electrophile and the nucleophile. The bibliography includes 433 references.

Dropping The Bomb? On Critical and Cinematic Reactions to Michael Ondaatje's The English Patient

OpenAIRE

Pesch, Josef

2018-01-01

This paper analyses Anthony Minghella's film adaptation of Michael Ondaatje’s The English Patient. It aims at establishing patterns of transformation and strategies of adaptation. Not only the nostalgie romanticisation, but also the de-politicisation of the novel is critically scrutinized. As dropping all reference to the atomic bomb from the film is the most blatant example of deviation from the novel, critical and political background is provided which may explain this act of self-censorshi...

A Study of Postmodern Narrative in Michael Cunningham's The Hours

Directory of Open Access Journals (Sweden)

Hajar Abbasi Narinabad

2012-09-01

Full Text Available This project aims at providing a detailed analysis of the major features of the theory of postmodern narrative and at going through the novel The Hours by the American writer Michael Cunningham concentrating on some postmodern narrative techniques. To do so, the researcher goes through the theories set forth by some postmodern theoreticians like Roland Barthes, Jacque Derrida, Jean-François Lyotard and Julia Kristeva to investigate the postmodern narrative techniques and elements used in the novel. The researcher first examines the theories and then critically applies them on the novel. The article goes through the most eminent elements of postmodern narrative including intertextuality, stream of consciousness style, fragmentation and representation respectively which are delicately utilized in The Hours. The article concludes by recommending a few directions for the further research.

The Great War and All That in A Hundred Doors by Michael Longley

Directory of Open Access Journals (Sweden)

Elisabeth Delattre

2015-03-01

Full Text Available The Great War has featured regularly in Michael Longley’s poetry, for personal, family, aesthetic and political reasons. His collection published in 2011 under the title A Hundred Doors contains a number of poems relating to his father and the so-called War Poets, in connection with others in which love and nature, life and death are also dominant themes. This article will show how, as elsewhere in his poetry, everything is interrelated, “the nature poetry”, in Longley’s words, “fertilizing the war poetry”.

LEBANON AFTER THE CEDAR REVOLUTION/ARE KNUDSEN AND MICHAEL KERR (eds; LEBANON: A HISTORY, 600--2011/by WILLIAM HARRIS

Directory of Open Access Journals (Sweden)

Franck Salameh

2013-05-01

Full Text Available LEBANON AFTER THE CEDAR REVOLUTION, ARE KNUDSEN AND MICHAEL KERR (eds; London: C. Hurst & Company, 2012. 323 pp. $29.95. LEBANON: A HISTORY, 600--2011, WILLIAM HARRIS; Oxford, New York: Oxford University Press, 2012. 360 pp. $34.95.

European Management: an emerging competitive advantage of European nations: A reply to Michael Porter

OpenAIRE

Bosch, Frans; Prooijen, A.A.

1992-01-01

textabstractThis article extends the debate begun in the June 1992 issue of EMJ when the authors first criticized Michael Porter's explanatory framework in his Competitive Advantage of Nations (1990), over the role of national culture on the competitive advantage of nations. In this paper, Frans van den Bosch and Arno van Prooijen stress that Europe is a locus of competitive advantage if one is prepared to pay attention to the possibility of ‘European Management’ as a potential asset of Europ...

Review: Cornelia Behnke & Michael Meuser (1999). Geschlechterforschung und qualitative Methoden [Gender Research and Qualitative Methods

OpenAIRE

Nicola Döring

2001-01-01

In less than 100 pages Cornelia BEHNKE and Michael MEUSER explain how gender studies evolved from women's studies and what feminist methodology is all about. They also discuss the interrelation of qualitative research and gender studies. The great potential of qualitative research based on a constructivist gender concept is demonstrated with a group discussion study involving different men only groups. Finally the authors deal with the question of how the researcher's gender affects both data...

Jack Michael's Appointments at the University of Houston and Arizona State University: Reflections from a Former Student

Science.gov (United States)

Mabry, John H.

2016-01-01

Jack Michael was an early enthusiast for what is now called applied behavior analysis. His many seminal contributions were through early publications in applied behavior analysis and the work of the students he trained (e.g., T. Ayllon, M. M. Wolf). His close mentorship of students earned him acclaim as a teacher along with his many theoretical…

Catalytic Enantioselective Synthesis of 3,4-Unsubstituted Thiochromenes through Sulfa-Michael/Julia-Kocienski Olefination Cascade Reaction.

Science.gov (United States)

Simlandy, Amit Kumar; Mukherjee, Santanu

2017-05-05

A highly enantioselective cascade sulfa-Michael/Julia-Kocienski olefination reaction between 2-mercaptobenzaldehydes and β-substituted vinyl PT-sulfones has been realized for the synthesis of 3,4-unsubstituted 2H-thiochromenes. This reaction, catalyzed by diphenylprolinol TMS ether, proceeds through an aromatic iminium intermediate and furnishes a wide range of 2-substiuted 2H-thiochromenes with excellent enantioselectivities (up to 99:1 er).

Tetrabutylammonium Bromide Media Aza-Michael Addition of 1,2,3,6-Tetrahydrophthalimide to Symmetrical Fumaric Esters and Acrylic Esters under Solvent-Free Conditions

Directory of Open Access Journals (Sweden)

Mohammadreza Zamanloo

2010-10-01

Full Text Available The aza-Michael addition of 1,2,3,6-tetrahydrophthalimide with symmetrical fumaric esters has been performed efficiently in a solvent-free system at 100 °C and using 1,4-diazabicyclo[2.2.2]octane (DABCO as a base in the presence of tetrabutylammonium bromide (TBAB. The products were obtained in good to high yields within 2.5-7.0 h. This reaction worked well on linear alkyl fumarates and was not effective with nonlinear alkyl fumarates. Although the reaction was also applicable to acrylates such as n-butyl acrylate, methacrylates and crotonates were not suitable Michael acceptors for this reaction.

Effective Integration of Technology and Instruction. Q&A with Michael Jay. REL Mid-Atlantic Educator Effectiveness Webinar Series

Science.gov (United States)

Regional Educational Laboratory Mid-Atlantic, 2015

2015-01-01

In this webinar, long-time educator and developer of education technology Michael Jay discussed the importance of using technology to support learning and gave examples of how teachers can integrate technology into their instruction based on the Common Core State Standards and the Next Generation Science Standards. The PowerPoint presentation and…

Ecossocialismo, romantismo e (autocrítica da modernidade em Michael Löwy

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Fabio Mascaro Querido

2008-12-01

Full Text Available Partindo da concreticidade da crise ecológica e das transformações contemporâneas no âmbito dos processos de acumulação capitalista, o objetivo geral deste artigo é versar algumas notas preliminares a propósito da perspectiva teórica e política do assim chamado ecossocialismo, tal qual formulado em Michael Löwy. “Corrente de pensamento e de ação” cuja resposta à crise ecológica, a um só tempo romântica e socialista, constitui igualmente uma crítica às potencialidades destrutivas contidas no interior do paradigma societário e produtivo da modernidade. Neste trajeto, busca -se uma aproximação à apropriação löwiniana da obra de Walter Benjamin, especialmente de sua crítica do “progresso” moderno e das ideologias apologetas da “modernização”. Almeja -se assim antever a forma através da qual Michael Löwy e os ecossocialistas respondem às profundas transformações da (pós modernidade capitalista contemporânea, com ênfase particular sobre um argumento central projetado na obra do intelectual franco -brasileiro, qual seja: a defesa da necessidade de que o marxismo radicalize “sua crítica da modernidade, do paradigma da civilização ocidental, industrial, moderna, burguesa” (LÖWY, 2000c, p.242, argumento que o levaria, já em meados da década de 1980, a valorizar as potencialidades revolucionárias subjacentes a crítica romântica da modernidade. Por fim, indaga -se sobre a projeção ecossocialista da necessidade de superação revolucionária do paradigma civilizatório propalado pelo capitalismo moderno

Asymmetric Domino Aza-Michael Addition/[3+2] Cycloaddition Reactions as a Versatile Approach to alpha,beta,gamma,-Triamino Acid Derivatives

Czech Academy of Sciences Publication Activity Database

Kapras, Vojtěch; Pohl, Radek; Císařová, I.; Jahn, Ullrich

2014-01-01

Roč. 16, č. 4 (2014), s. 1088-1091 ISSN 1523-7060 Institutional support: RVO:61388963 Keywords : 1,3-dipolar cycloaddition * lithium amides * aza-Michael addition * amino acids * pyrazoles Subject RIV: CC - Organic Chemistry Impact factor: 6.364, year: 2014

Athlete endorsement as a marketing strategy: a case study of Nike and Michael Jordan

OpenAIRE

Masár Vieites, Laura Virginia

2014-01-01

Les empreses intenten obrir mercats nous constantment, aconseguint atraure nous clients objectiu i augmentar el reconeixement de la marca. Aquest treball investiga el cóm i per què el patrocini d'atletes, per a que aquests representin els productes d'una empresa, ja que és una eina cada vegada més àmplia i popular en el màrqueting mix de les empreses. Michael Jordan, un estel retirada de bàsquet, ha rebut molta atenció dels mitjans publicitaris i ha representat sota patrocini a diversos produ...

Late Quaternary vegetation and climate history of the central Bering land bridge from St. Michael Island, western Alaska

Science.gov (United States)

Ager, T.A.

2003-01-01

Pollen analysis of a sediment core from Zagoskin Lake on St. Michael Island, northeast Bering Sea, provides a history of vegetation and climate for the central Bering land bridge and adjacent western Alaska for the past ???30,000 14C yr B.P. During the late middle Wisconsin interstadial (???30,000-26,000 14C yr B.P.) vegetation was dominated by graminoid-herb tundra with willows (Salix) and minor dwarf birch (Betula nana) and Ericales. During the late Wisconsin glacial interval (26,000-15,000 14C yr B.P.) vegetation was graminoid-herb tundra with willows, but with fewer dwarf birch and Ericales, and more herb types associated with dry habitats and disturbed soils. Grasses (Poaceae) dominated during the peak of this glacial interval. Graminoid-herb tundra suggests that central Beringia had a cold, arid climate from ???30,000 to 15,000 14C yr B.P. Between 15,000 and 13,000 14C yr B.P., birch shrub-Ericales-sedge-moss tundra began to spread rapidly across the land bridge and Alaska. This major vegetation change suggests moister, warmer summer climates and deeper winter snows. A brief invasion of Populus (poplar, aspen) occurred ca. 11,000-9500 14C yr B.P., overlapping with the Younger Dryas interval of dry, cooler(?) climate. During the latest Wisconsin to middle Holocene the Bering land bridge was flooded by rising seas. Alder shrubs (Alnus crispa) colonized the St. Michael Island area ca. 8000 14C yr B.P. Boreal forests dominated by spruce (Picea) spread from interior Alaska into the eastern Norton Sound area in middle Holocene time, but have not spread as far west as St. Michael Island. ?? 2003 University of Washington. Published by Elsevier Inc. All rights reserved.

What I Think I May Have Learned--Reflections on 50 Years of Teaching: An Interview with Michael Wertheimer

Science.gov (United States)

Michael, Kurt D.

2006-01-01

Kurt Michael is an associate professor in the Department of Psychology at Appalachian State University (ASU) where he teaches history and systems of psychology, abnormal psychology, child psychopathology, and interventions for children and adolescents. He received his BA (cum laude) from the University of Colorado at Boulder and his MS and PhD in…

Synthesis of l-threitol-based crown ethers and their application as enantioselective phase transfer catalyst in Michael additions.

Science.gov (United States)

Rapi, Zsolt; Nemcsok, Tamás; Pálvölgyi, Ádám; Keglevich, György; Grün, Alajos; Bakó, Péter

2017-06-01

A few new l-threitol-based lariat ethers incorporating a monoaza-15-crown-5 unit were synthesized starting from diethyl l-tartrate. These macrocycles were used as phase transfer catalysts in asymmetric Michael addition reactions under mild conditions to afford the adducts in a few cases in good to excellent enantioselectivities. The addition of 2-nitropropane to trans-chalcone, and the reaction of diethyl acetamidomalonate with β-nitrostyrene resulted in the chiral Michael adducts in good enantioselectivities (90% and 95%, respectively). The substituents of chalcone had a significant impact on the yield and enantioselectivity in the reaction of diethyl acetoxymalonate. The highest enantiomeric excess (ee) values (99% ee) were measured in the case of 4-chloro- and 4-methoxychalcone. The phase transfer catalyzed cyclopropanation reaction of chalcone and benzylidene-malononitriles using diethyl bromomalonate as the nucleophile (MIRC reaction) was also developed. The corresponding chiral cyclopropane diesters were obtained in moderate to good (up to 99%) enantioselectivities in the presence of the threitol-based crown ethers. © 2017 Wiley Periodicals, Inc.

A Symposium on the Relevance of Michael Polanyi's Insights to a Reformulated Understanding of Science, Technology, and Society

Science.gov (United States)

Mead, Walter B.

2011-01-01

This is intended as an introductory statement to the explorations undertaken in the essays that follow. The authors of these essays attempt to introduce the reader to some of the insights of Michael Polanyi and their implications for the reader who wishes to come to a greater understanding of modern technological society, which--for better or…

Pop / Tõnu Kaalep

Index Scriptorium Estoniae

Kaalep, Tõnu, 1966-2018

2005-01-01

Uutest heliplaatidest Andy Bell "The Electric Blue", Vex'd "Degenerate", "Hendrik Sal-Saller & Estonian Dream Bigband", Ian Brown "The Greatest", Jon Lennon "Working Class Hero", Richard Youngs "The Naive Shaman"

78 FR 69113 - Statutorily Mandated Designation of Difficult Development Areas for 2014

Science.gov (United States)

2013-11-18

... identical (to four decimal places) to the last area selected, and its inclusion resulted in only a minor... designated and on geographic definitions, contact Michael K. Hollar, Senior Economist, Economic Development..., 2000 Census, and Metropolitan Area Definitions Data from the 2010 Census on total population of...

Four Papers on Contemporary Software Design Strategies for Statistical Methodologists

OpenAIRE

Carey, Vincent; Cook, Dianne

2014-01-01

Software design impacts much of statistical analysis and, as technology changes, dramatically so in recent years, it is exciting to learn how statistical software is adapting and changing. This leads to the collection of papers published here, written by John Chambers, Duncan Temple Lang, Michael Lawrence, Martin Morgan, Yihui Xie, Heike Hofmann and Xiaoyue Cheng.

Polyfunctional beta-Dicarbonyl Compounds by Michael Addition Reactions of Ester Enolates to alpha-Benzylidene and alpha-Alkylidene-beta-dicarbonyl Compounds

Czech Academy of Sciences Publication Activity Database

Holan, Martin; Pohl, Radek; Císařová, I.; Jahn, Ullrich

-, č. 18 (2012), s. 3459-3475 ISSN 1434-193X R&D Projects: GA ČR GA203/09/1936 Institutional research plan: CEZ:AV0Z40550506 Keywords : Michael addition * diastereoselectivity * regioselectivity * enols * dicarbonyl compounds Subject RIV: CC - Organic Chemistry Impact factor: 3.344, year: 2012

Michael Field’s “A Dance of Death”

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LeeAnne Richardson

2012-03-01

Full Text Available The 1912 poem "A Dance of Death" by Michael Field (pen name of Katherine Bradley and her niece Edith Cooper depicts Salome in an alternate version of the biblical story: this Salome dances on a frozen river, falls through the ice, and is decapitated on a jagged edge. Nonetheless, her beautiful head continues dancing over the frozen river. This poem is highly unusual, especially in the context of the other poems in the postconversion volume Poems of Adoration, because it questions, rather than submits to, authority. In re-writing a familiar Christian tale, as well as a familiar decadent theme, Field uses the poem to assert the supremacy of their artistic vision, which (despite their ardent Catholicism cannot be subject to any law outside themselves. Like the continually dancing head of Salome, which continues to create beauty even after nature (and perhaps God has struck it down, the poet is subjugate only to her own law and creates without boundaries or restrictions on her art. Bradley and Cooper were acutely aware of their authorial persona (actively taking not only a masculine but also a singular poetic identity, and their mode of reconciling the apparent contradictions of this identity are mirrored in their presentation of Salome in a "Dance of Death."

Race, punishment, and the Michael Vick experience.

Science.gov (United States)

Piquero, Alex R; Piquero, Nicole Leeper; Gertz, Marc; Baker, Thomas; Batton, Jason; Barnes, J C

2011-01-01

Objective. The relationship between race and crime has been contentious, focusing primarily on offending and incarceration patterns among minorities. There has been some limited work on public perceptions of criminal punishment, and findings show that while minorities believe in the role and rule of law, they simultaneously perceive the justice system as acting in a biased and/or unfair manner. Two limitations have stalled this literature. First, research has focused mainly on criminal punishments to the neglect of noncriminal punishments. Second, most studies have not examined whether race remains salient after considering other demographic variables or discrimination and legitimacy attitudes.Methods. Using data from 400 adults, we examine how race affects perceptions of criminal punishment and subsequent reinstatement into the National Football League in the case of Michael Vick, a star professional quarterback who pled guilty to charges of operating an illegal dog-fighting ring.Results. Findings show that whites are more likely to view Vick's punishment as too soft and that he should not be reinstated, while nonwhites had the opposite views. Race remained significant after controlling for other variables believed to be related to punishment perceptions.Conclusion. Attitudes toward both criminal punishment and NFL reinstatement vary across race such that there exists important divides in how individuals perceive the system meting out punishment and subsequently reintegrating offenders back into society. These results underscore that white and nonwhites perceive the law and its administration differently.

77 FR 59629 - Statutorily Mandated Designation of Difficult Development Areas for 2013

Science.gov (United States)

2012-09-28

... ranking ratio, as described above, was identical (to four decimal places) to the last area selected, and... questions on how areas are designated and on geographic definitions, contact Michael K. Hollar, Senior... year. 2010 Census, 2000 Census, and Metropolitan Area Definitions Data from the 2010 Census on total...

Popmuusika / Mart Juur

Index Scriptorium Estoniae

Juur, Mart, 1964-

2005-01-01

Uutest heliplaatidest John Lennon "Working Class Hero", Tito Puente y Su Orchestra "Viva Mambo", Sigur Ros "Takk", Ladytron "Witching Hour", Black Rebel Motorcycle Club "Howl", Ans. Andur "Tuled peale", Emmilou Harris "Heartaches & Highways"

Trajetória acadêmica e perspectivas acerca do turismo sob o olhar de Colin Michael Hall

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Elayne Gouveia da Silva

2016-04-01

Full Text Available Este trabalho versa sobre a visão do Colin Michael Hall na temática do turismo. Para analisar essa temática imbricou-se em duas leituras principais como parâmetro para a discussão. A primeira é a obra “Planejamento turístico: política, processo e planejamento” e, a segunda, “Turismo como El Ciencia Social de La Movilidade”. Estas obras marcam a mudança de visão do autor, onde o mesmo se dedica a fomentar um novo olhar sobre o turismo suscitando sete aspectos para se pensar no turismo. O objetivo deste artigo é analisar a visão de Colin Michael Hall acerca do Turismo. Como metas intermediárias pretende-se, a partir da compilação de informações sobre sua vida acadêmica e suas principais contribuições realizar uma breve crítica. Para o trabalho utilizou-se a pesquisa bibliográfica, e entrevista com o autor. Como resultado obteve-se uma reunião das principais ideias e posições ideológicas do autor, e algumas de suas contribuições com o estudo do turismo.

Entrevista com Mathieu Dosse, Gian Luigi de Rosa e Michael Kegler

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Andréia Guerini

2017-09-01

Full Text Available O conjunto das três entrevistas que seguem aborda a mesma temática, isto é, aspectos de tradução/adaptação em geral e da tradução do romance Estive em Lisboa e lembrei de você de Luiz Ruffato em particular. O romance de Ruffato foi escrito em 2009, editado em Portugal (Quetzal, 2010 e traduzido para diferentes línguas, como italiano (La Nuova Frontiera, 2011, espanhol (Eterna Cadencia, 2011, francês (Chandeigne, 2015, alemão (Assoziation A, 2016 e, nos próximos meses será publicado em finlandês (Into. O livro foi adaptado para o cinema em 2015, pelo cineasta português José Barahona, sendo exibido em festivais nacionais e internacionais. As entrevistas abaixo foram feitas com os tradutores Gian Luigi De Rosa, Mathieu Dosse e Michael Kegler em 2016. Gian Luigi De Rosa (Itália/1969-- possui doutorado em “Culture e Istituzioni dei paesi di lingue iberiche in età moderna e contemporanea” e é professor de português na Universidade do Salento, em Lecce. É autor de livros e ensaios sobre língua e linguística portuguesa, literatura portuguesa e brasileira e tradução audiovisual e intersemiótica. É também responsável pela elaboração das legendas em italiano do filme Estive em Lisboa e lembrei de você. Mathieu Dosse (Brasil/1978-- é formado pela Université Paris 8, onde estudou Teoria da Tradução. Traduziu para o francês Graciliano Ramos, Luiz Ruffato e João Guimarães Rosa. Michael Kegler (Alemanha/1967-- estudou literatura brasileira e portuguesa na universidade de Frankfurt, sem concluir o curso. Trabalhou como livreiro no Centro do Livro de Língua Portuguesa, antes de se tornar tradutor literário. Traduziu para o alemão José Eduardo Agualusa, Moacyr Scliar, Luiz Ruffato, entre outros autores. Em julho de 2016, junto com Ruffato, recebeu o prêmio literário Hermann Hesse na Alemanha, pela qualidade da obra publicada em conjunto com a sua tradução.

An Oral History Interview with MICHAEL M. CERNEA (interviewer: Judith Freidenberg

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MICHAEL M. CERNEA

2008-01-01

Full Text Available The editors and editorial board of Human Organization are pleased to introduce readers to the following oral history interview with Michael M. Cernea, a development social scientist who has militated throughout his academic career and applied work for "putting people first", in the forefront of development projects and policies. Working for a long time for the promotion of anthropological and sociological knowledge, either in the activities of the World Bank or in the policies and programs of governments of both developed and developing countries, Dr. Cernea cleared pathways for applied social science that are sure to benefit people in development settings for many years to come. Undoubtedly many readers already know Dr. Cernea's work well, especially those of us who teach the anthropology of development or work in applied settings and organizations, but this interview embeds his broad body of work into a personal, human, and at times tragic context that opens with brushes with death, Nazi brutality, and exile. It also provides valuable insights for carrying out the work of development anthropologists within large-scale organizations and governments.This interview with Dr. Cernea was conducted by Dr. Judith Freidenberg, of the University of Maryland, on June 30, 2003, for the Society for Applied Anthropology Oral History Project, headquartered at the University of Kentucky Libraries. This Project aims to create, through the vehicle of oral histories, a record of the life, activities and experiences of number of selected scholars-anthropologists who devoted a great part of their scientific work to research, to applied work in different settings, to inducing development, including to hands-on work on crafting public social policies and actual development programs. The present transcript of the interview was reviewed by both participants for editorial purposes. Michael M. Cernea expanded some of his oral responses, for historical accuracy or to add

Väljaspool iseennast / Aita Kivi

Index Scriptorium Estoniae

Kivi, Aita, 1954-

2000-01-01

Sisu : Jaan Kaplinski. Silm. Hektor; John Grisham. Aguliadvokaat; Kerttu Rakke. Kalevipoeg; luulekogu "Armastuse valgus", koost. Peep Ilmet; James Woodall. John Lennon ja Yoko Ono; Donald Braider. El Greco eraelu; Åke Edwardson. Tants ingliga

Inverting the diastereoselectivity of the mukaiyama-michael addition with graphite-based catalysts

KAUST Repository

Acocella, Maria Rosaria

2014-02-07

Here, we show that graphite-based catalysts, mainly graphite oxide (GO) and exfoliated GO, are effective recyclable catalysts for a relevant stereoselective Mukaiyama-Michael addition, outperforming currently available catalysts. Moreover, the graphite-based catalysts described here invert the diastereoselectivity relative to that observed with known catalysts, with the unprecedented large prevalence of the anti diastereoisomer. This inverted diastereoselectivity is increased when the catalyst concentration is reduced and after catalyst recycling. Density functional theory calculations suggest that the selectivity is determined by two types of supramolecular interactions operating between the catalyst and the substrates at the diastereoselectivity- determining transition state, specifically, the π-stacking of b-nitrostyrene with graphite and the van der Waals interaction between the SiMe3 group of the silyl ether and the graphite. © 2013 American Chemical Society.

Michael Jäckel, Julia Derra, Cornelia Eck: SchönheitsAnsichten. Geschlechterbilder in Werbeanzeigen und ihre Bewertung. Baden-Baden: Nomos Verlag 2009.

Directory of Open Access Journals (Sweden)

Waltraud Posch

2010-11-01

Full Text Available Michael Jäckel, Julia Derra, and Cornelia Eck’s cross-generational study answers the question as to which concepts of beauty are presented in magazine advertisements and how recipients react to these concepts. The book provides an important basis for Media Studies and Gender Sociology particularly because it also shows medial constructions of gender that are initially invisible and because it shows gender related illustrations of physicality and beauty.In einer generationenübergreifenden Studie gehen Michael Jäckel, Julia Derra und Cornelia Eck der Frage nach, welche Schönheitsbilder in der Zeitschriftenwerbung präsentiert und wie diese von Rezipient/-innen aufgenommen werden. Das Buch liefert eine wichtige Basis für Medienforschung und Soziologie der Geschlechter, zumal es auch vordergründig nicht sichtbare mediale Konstruktionen von Geschlecht und die geschlechtsbezogene Darstellung von Körperlichkeit und Schönheit aufzeigt.

Michael Novak's "Business as a Calling" as a Vehicle for Addressing Ethical and Policy Concerns in a Business Law Course

Science.gov (United States)

Murphy, Tonia Hap

2008-01-01

This article describes the author's experience of incorporating Michael Novak's "Business as a Calling: Work and the Examined Life" into a Business Law course. The author views it as a positive addition to the course, one that may be of interest to her colleagues at other institutions. Accordingly, after an overview of Novak's analysis in…

Aza-Peptidyl Michael Acceptor and Epoxide Inhibitors—Potent and Selective Inhibitors of Schistosoma mansoni and Ixodes ricinus Legumains (Asparaginyl Endopeptidases)

Czech Academy of Sciences Publication Activity Database

Ovat, A.; Muindi, F.; Fagan, C.; Brouner, M.; Hansell, E.; Dvořák, J.; Sojka, Daniel; Kopáček, Petr; McKerrow, J. H.; Caffrey, C. R.; Powers, J. C.

2009-01-01

Roč. 52, č. 22 (2009), s. 7192-7210 ISSN 0022-2623 R&D Projects: GA ČR GA206/06/0865; GA MŠk(CZ) LC06009 Institutional research plan: CEZ:AV0Z60220518 Keywords : legumain * IrAE * aza-peptide Michael acceptors Subject RIV: EC - Immunology Impact factor: 4.802, year: 2009

Tandem Aldol-Michael Reactions in Aqueous Diethylamine Medium: A Greener and Efficient Approach to Bis-Pyrimidine Derivatives

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Abdullah M. Al-Majid

2013-12-01

Full Text Available A simple protocol, involving the green synthesis for the construction of novel bis-pyrimidine derivatives, 3a–i and 4a–e are accomplished by the aqueous diethylamine media promoted tandem Aldol-Michael reaction between two molecules of barbituric acid derivatives 1a,b with various aldehydes. This efficient synthetic protocol using an economic and environmentally friendly reaction media with versatility and shorter reaction time provides bis-pyrimidine derivatives with high yields (88%–99%.

Sosiale motiewe en stereotipering in verbruikers se keuse van groot ...

African Journals Online (AJOL)

S Blignaut

86). Volgens Hawkins et ... Burns en Lennon (1993) lok die sinsvoltooiingstegniek direkte reaksie by subjekte uit, dus die reaksie wat ..... FERBER, R (1974): Handbook of marketing research. New. York. McGraw-Hill. FISKE, ST & TAYLOR, SE ...

Constructing Singapore : Elitism, Ethnicity and the Nation-Building Project, Michael D. Barr & Zlatko Skrbis

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Jean-Louis Margolin

2010-12-01

Full Text Available Michael Barr, seul ou en collaboration, est depuis une décennie l’un des auteurs les plus prolifiques et les plus reconnus sur la structuration politique et sociologique du Singapour contemporain. Longtemps attaché à l’université du Queensland (Brisbane, aujourd’hui à Flinders (Adelaide, il est assez représentatif de la nouvelle génération (singapourienne aussi bien qu’étrangère des spécialistes de la cité-état : fermement critique, et parfois même hyper-critique, elle n’en reconnaît pas m...

Michael Oakeshott´s Work as a Liberal-Conserv ative Paradigm

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Josep Baqués

2014-01-01

Full Text Available As is the case with other thinkers linked to what can be broadly defined as conservatism, it is arguable whether Michael Oakeshott was just a conservative, or whether he was also a liberal. He often rejected this last label. He also tried to avoid the classic debate between the left/right wing divide, conferring instead a mantle of neutrality on his work. This analysis shows, on the one hand, that Oakeshott´s work is ideologically orientated and, on the other hand, that it contains a substantial liberal component. In fact, he offered a liberal-conservative synthesis in which the free market appears to be not only the best, but the only feasible outcome in the proposed scenario of political prudence. I will fi rst connect Oakeshott with the main traditions of thought, then analyse the theoretical implications of his position, and finally explore the consequences derived from all this for everyday political practice.

The role of Michael Pupin in solving of Serbian national question

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Grčić Mirko D.

2004-01-01

Full Text Available Michael I. Pupin was a professor at the University of Columbia, member and the president of Academy of Science in New York; one of the esteemed members of USA National Academy of Science; member and president of many experts and scientific institutions and societies in the USA; member of State Council for Scientific Research by president of the USA during the World War I. Of the great importance for political geography and geopolitics was his activity in Paris during the Peace Conference after the World War I in 1919 also as his great contribution to establishment of state borders of Kingdom of Serbs, Croats and Slovenians (later Yugoslavia, which helped those nations to establish their national borders at maximum level. Pupin claimed that he was Yugoslav patriot and American citizen. Role of M. Pupin in battle for national interests and Yugoslav borders after the World War I is shown in this article.

Lizards, ticks and contributions to Australian parasitology: C. Michael Bull (1947-2016).

Science.gov (United States)

Godfrey, Stephanie S; Gardner, Michael G

2017-12-01

Professor C. Michael Bull was a great scientist and mentor, and an Associate Editor of this journal. While his research career spanned the fields of behavioural ecology, conservation biology and herpetology, in this article, we pay tribute to his major contribution to Australian parasitology. Mike authored more than eighty articles on host-parasite ecology, and revealed major insights into the biology and ecology of ticks from his long term study of the parapatric boundary of two tick species ( Amblyomma limbatum and Bothriocroton hydrosauri ) on the sleepy lizard ( Tiliqua rugosa ). In this article, we provide an overview of how this research journey developed to become one of the longest-running studies of lizards and their ticks, totalling 35 years of continuous surveys of ticks on lizards, and the insights and knowledge that he generated along that journey.

Stereoselective synthesis of organosulfur compounds incorporating N-aromatic heterocyclic motifs and quaternary carbon centers via a sulfa-Michael triggered tandem reaction.

Science.gov (United States)

Qin, Tianyou; Cheng, Lu; Zhang, Sean Xiao-An; Liao, Weiwei

2015-06-14

A novel sulfa-Michael addition (SMA)-triggered tandem reaction was developed by combining a SMA reaction with a simultaneous rearomatization process utilizing a less reactive carbonyl group as an intramolecular electrophile partner, which provided a unique synthetic route to access various organosulfur compounds incorporating an N-aromatic heterocyclic motif and quaternary carbon centers.

'Introducing Michael Gove to Loïc Wacquant': Why Social Work Needs Critical Sociology.

Science.gov (United States)

Michael Garrett, Paul

2016-06-01

In 2013, Michael Gove, then Secretary of State for Education and Health in the UK coalition government, criticised social workers for laying insufficient emphasis on the 'agency' of individuals and for being too preoccupied with social and economic inequalities. Such a perspective, which is not unique to Gove, needs to be countered by reaffirming the significance of an expansively critical sociology for social work. In this context, the thematic concerns of the French theorist, Loïc Wacquant, illuminates key aspects of social work engagement with clients which Gove and his ideological associates appear intent on ignoring. The issues raised have significant political resonances given the pending UK General Election taking place in May 2015.

Rationalism and traditionalism in politics. The correspondence between Karl R. Popper and Michael Oakeshott

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Spartaco Pupo

2016-07-01

Full Text Available The correspondence of 1948 between Karl Popper and Michael Oakeshott, translated for the first time in Italian and published in the appendix to this paper, demonstrates the existence of two different ways of thinking about politics: the rationalist approach, founded on the “argumentation” as a rational means for the non-violent solution of problems (Popper, and the traditionalist mode, inspired by the method of “conversation” as a guarantee of constant openness to the diversity of identities (Oakeshott. To rise from the letters is a mutual influence on the interpretation of the key concepts that characterize the thought of the two authors, which however does not cancel the fundamental divergence of their political orientation.

Using Our Voices, Losing Our Bodies: Michael Brown, Trayvon Martin, and the Spirit Murders of Black Male Professors in the Academy

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Johnson, Lamar; Bryan, Nathaniel

2017-01-01

The recent deaths of Michael Brown, Trayvon Martin, and other Black males have generated new civil rights urgencies in Black communities and spirited academic discourses in higher education regarding the educational and social plight of Black males in America. Connecting the deaths of Black males to our lived experiences in the academy, we use a…

Solar building study. Summary report. St. Michael`s Close, Harlow

Energy Technology Data Exchange (ETDEWEB)

1992-12-31

Designed and developed by Harlow Council as an admirable attempt to reduce the energy consumption of its large housing stock, this building represents a quality alternative to the bland stereotype of local authority housing. Well liked for its appearances and other amenity benefits the building in practice is a failure. This failure, which manifests itself in extreme and unnecessary overheating of habitable areas of the building, originates in the lack of division between the conservatory and the rest of the building. Any condition that exists in the former area quickly transmits itself to the latter. The dropping of dividing doors and glazing, that would have enabled the isolation of the conservatory from adjacent habitable areas, was a decision made during the design stage on cost grounds for a saving of approximately 2000 pounds. (author)

Enantioselective organocatalyzed Oxa-Michael-Aldol cascade reactions: Construction of chiral 4H-chromenes with a trifluoromethylated tetrasubstituted carbon stereocenter

KAUST Repository

Zhang, Jing

2015-03-13

The first organocatalytic asymmetric synthesis of 4H-chromenes bearing a trifluoromethylated tetrasubstituted carbon center is presented. Chiral secondary amines promote the oxa-Michael-aldol cascade reaction between alkynals and 2-trifluoroacetylphenols via iminium-allenamine activation to produce pharmaceutically important heterocycles with excellent enantioselectivities. The proposed reaction can be scaled-up easily with maintenance of the excellent enantioselectivity. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A key and a hero : An essay on the current state of urban design

NARCIS (Netherlands)

Calabrese, L.M.

2011-01-01

This issue of Atlantis highlights the ‘old question’ of urban form and the role of Urban Design within it. This is not without reason. In the past decades remarkably negative opinions were voiced on the urban condition and particularly on public space. In the 1990s Michael Sorkin’s well known

Nacionalismos e internacionalismo: um debate entre Michael Löwy e Michel Cahen

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Ângela Lazagna

2008-11-01

Full Text Available Este artigo consiste em um debate realizado entre Michel Löwy e Michael Cahen em meados dos anos 1990 e revisto para esta publicação. Mesmo que a discussão refira-se a acontecimentos que até certo ponto podem ser considerados datados, a preocupação de fundo que é comum a esses artigos concede-lhes atualidade: a necessidade do aprofundamento de uma reflexão, a partir da teoria marxista, sobre o problema dos nacionalismos e do internacionalismo em tempos de mundialização. Esse aprofundamento, segundo os autores, faz-se necessário sobretudo por meio de uma reflexão que rompa criticamente com uma visão eurocêntrica dos diferentes nacionalismos e que supere a atitude de muitos marxistas de desprezarem tudo aquilo que não seja diretamente relevante à "consciência de classe".

Principles of Chemistry (by Michael Munowitz)

Science.gov (United States)

Kovac, Reviewed By Jeffrey

2000-05-01

At a time when almost all general chemistry textbooks seem to have become commodities designed by marketing departments to offend no one, it is refreshing to find a book with a unique perspective. Michael Munowitz has written what I can only describe as a delightful chemistry book, full of conceptual insight, that uses a novel and interesting pedagogic strategy. This is a book that has much to recommend it. This is the best-written general chemistry book I have ever read. An editor with whom I have worked recently remarked that he felt his job was to help authors make their writing sing. Well, the writing in Principles of Chemistry sings with the full, rich harmonies and creative inventiveness of the King's Singers or Chanticleer. Here is the first sentence of the introduction: "Central to any understanding of the physical world is one discovery of paramount importance, a truth disarmingly simple yet profound in its implications: matter is not continuous." This is prose to be savored and celebrated. Principles of Chemistry has a distinct perspective on chemistry: the perspective of the physical chemist. The focus is on simplicity, what is common about molecules and reactions; begin with the microscopic and build bridges to the macroscopic. The author's perspective is clear from the organization of the book. After three rather broad introductory chapters, there are four chapters that develop the quantum mechanical theory of atoms and molecules, including a strong treatment of molecular orbital theory. Unlike many books, Principles of Chemistry presents the molecular orbital approach first and introduces valence bond theory later only as an approximation for dealing with more complicated molecules. The usual chapters on descriptive inorganic chemistry are absent (though there is an excellent chapter on organic and biological molecules and reactions as well as one on transition metal complexes). Instead, descriptive chemistry is integrated into the development of

What's in a Name? That Which We Call a Crisis? A Commentary on Michael Young's Article "Overcoming the Crisis in Curriculum Theory"

Science.gov (United States)

Lundgren, Ulf P.

2015-01-01

Michael Young's article "Overcoming the crisis in curriculum theory: a knowledge-based approach" ("JCS, 45", 2) is discussed from the starting point that the claimed crisis is constructed from a decisive solution, that is the solution determines what is a crisis. But curriculum research and curriculum theory are in need of…

Optical Interference Coatings Design Contest 2007: triple bandpass filter and nonpolarizing beam splitter.

Science.gov (United States)

Tilsch, Markus; Hendrix, Karen

2008-05-01

A triple bandpass filter (28 solutions received) and a nonpolarizing beam splitter (23 solutions received) were the subjects of the design contest held in conjunction with the 2007 Optical Interference Coatings topical meeting of the Optical Society of America. Fifteen designers participated using a wide spectrum of design approaches and optimization strategies to create the submissions. The results differ significantly, but all meet the contest requirements. Fabien Lemarchand wins both contests by submitting the thinnest (6254 nm) triple bandpass design and the widest (61.7 nm) nonpolarizing beam-splitter design. Michael Trubetskov is in second place, followed by Vladimir Pervak in both contests. The submitted designs are described and evaluated.

Maailma enim teenivad surnud kuulsused / Pille-Mai Helemäe

Index Scriptorium Estoniae

Helemäe, Pille-Mai

2008-01-01

Forbesi andmetel maailma enim raha teenivate surnud kuulsuste seas ka lauljad Elvis Presley (1935-1977), John Lennon (1940-1980), George Harrison (1943-2001), Tupac Shakur (1971-1996) ja näitlejad Marilyn Monroe (1926-1962), Steve McQueen (1930-1980)

A propósito del libro "Accounting theory: research, regulation and accounting practice" de Michael Gaffikin

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Garcia Nohora

2012-09-01

Full Text Available En el libro “Accounting theory: research, regulation and accounting practice”, el profesor australiano Michael Gaffikin ofrece al lector una idea del origen y amplio desenvolvimiento de la teoría contable durante el siglo XX “cuyo desarrollo ha sido dominado por Estados Unidos” (Gaffikin, 2008, p. 32. Plantea, igualmente, los desafíos y problemas actuales de la regulación y la profesión contable. Por ejemplo, el autor precisa que ante la incapacidad de lograr un acuerdo sobre las mediciones apropiadas, la tendencia mundial es a instaurar medidas determinadas arbitrariamente (Gaffikin, 2008, p. 154.

Advances in Statistical Control, Algebraic Systems Theory, and Dynamic Systems Characteristics A Tribute to Michael K Sain

CERN Document Server

Won, Chang-Hee; Michel, Anthony N

2008-01-01

This volume - dedicated to Michael K. Sain on the occasion of his seventieth birthday - is a collection of chapters covering recent advances in stochastic optimal control theory and algebraic systems theory. Written by experts in their respective fields, the chapters are thematically organized into four parts: Part I focuses on statistical control theory, where the cost function is viewed as a random variable and performance is shaped through cost cumulants. In this respect, statistical control generalizes linear-quadratic-Gaussian and H-infinity control. Part II addresses algebraic systems th

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α′-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones

Science.gov (United States)

Pal, Rammohan; Das Gupta, Arpita; Mallik, Asok K.

2012-01-01

Iodine-catalyzed reaction of indoles with α,α′-bis(arylmethylene)cyclopentanones afforded one diastereomer of the corresponding Michael adducts, namely, E-2-(3-indolylphenylmethyl)-5-phenylmethylenecyclopentanones, in a good yield. The products form a new group of indole derivatives. PMID:24052849

El pluralismo y la desigualdad educativa en México. La teoría de la justicia de Michael Walzer

OpenAIRE

Aguilar-Sahagún, Luis A.

2003-01-01

El presente estudio intenta ofrecer elementos de una teoría sobre la justicia que ilumine los graves problemas de la desigualdad educativa en México. Se trata de la propuesta del filósofo estadunidense Michael Walzer, quien con su obra "Esferas de la justicia. Defensas del pluralismo y la igualdad" ha abierto un horizonte que ha fecundado la discusión sobre este concepto en el contexto del llamado debate liberalismo- comunitarismo.

A Musical Italy: Michael W. Balfe’s Italian Experiences

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Basil Walsh

2016-06-01

Full Text Available The Dublin-born musician, Michael W. Balfe, was a singer, composerand conductor whose brilliant musical career was heavily influenced byformative experiences in Italy. In 1825, Balfe, interested in broadeninghis musical studies first went to Paris where he was introduced to thegreat composers, Luigi Cherubini and Gioachino Rossini, who took apersonal interest in him and his musical talents. On the advice of Rossinihe spent the next few years in Italy studying singing with the famousRossini singer, Filippo Galli, and taking music composition lessonsfrom Ferdinando Paer, in Rome. Later in Milan he studied harmonyand counterpoint with Vincenzo Federici. By 1831, when he was only23 years old, his first three operas had been produced in Palermo, Pavia,and Milan. He returned to London in August 1835, participatingwith the great Lablache, Tamburini, Rubini and Grisi in a concert inVauxhall Gardens. In 1834 he made his debut at La Scala, Milan, singingopposite the renowned mezzo-soprano, Maria Malibran in Rossini’sOtello. He appeared again with Malibran in Venice early in 1835,singing once more in Rossini and Bellini operas. Balfe worked as a singerand composer throughout the Italian peninsula/states during the years,1825-1835 and this article will chart these experiences and demonstratehow the time he spent in Italy and the people he met, influenced hislife and later career as an important and popular European composer.

Michael Fordham and the Journal of Analytical Psychology: the view from Hangman's Hill.

Science.gov (United States)

Urban, Elizabeth

2015-09-01

This short paper was presented to a conference in honour of the 60(th) year of the JAP and was one of others that acknowledged the contribution of Michael Fordham. The subtitle refers to the paper's overview of Fordham's published oeuvre and the particular place of the Journal of Analytical Psychology, for which he was the founding editor. Fordham's contribution to a Jungian-based model of development is discussed, with reference to his papers in the British Journal of Medical Psychology. The paper notes miscellaneous pieces from Fordham's commentaries, obituaries, papers and reviews which capture not only the development of Fordham as a thinker but also his character. There is discussion of his reviews of Melanie Klein's Envy and Gratitude and manuscripts by Erich Neumann. A reminiscence of Fordham as supervisor is recounted. © 2015, The Society of Analytical Psychology.

Modalities of representation and perception in Michael Ondaatje’s Anil’s Ghost

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Sigrid Renaux

2017-01-01

Full Text Available http://dx.doi.org/10.5007/2175-8026.2017v70n1p113 This study analyses the way in which the interdependence of the representation and perception of reality is exemplified and questioned in Michael Ondaatje’s Anil’s Ghost (2000. As we enter this work of resistance literature by way of an omniscient narrator, we enter not just the geographical spaces and cultural history of Sri Lanka, but find ourselves taking part in the daily struggle of the people to survive, to identify and do justice to the many dead in this conflict between ethnic groups and the government. This fragmentation of the narrative structure – casting doubt on the conflicting relationships established between the characters’ present and the past, between western and eastern values in relation to the concept of truth, the search for lost identity and love – highlights still further the interchangeability of representation and perception of reality.

Domino Aza-Michael-ih-Diels-Alder Reaction to Various 3-Vinyl-1,2,4-triazines: Access to Polysubstituted Tetrahydro-1,6-naphthyridines.

Science.gov (United States)

Jouha, Jabrane; Buttard, Floris; Lorion, Magali; Berthonneau, Clément; Khouili, Mostafa; Hiebel, Marie-Aude; Guillaumet, Gérald; Brière, Jean-François; Suzenet, Franck

2017-09-15

A straightforward domino aza-Michael-inverse-electron-demand-hetero-Diels-Alder/retro-Diels-Alder reaction between primary and secondary propargylamine derivatives and 3-vinyl-1,2,4-triazines is developed highlighting not only the uniqueness of this dual-heterocyclic platform but also a novel and unprecedented path to polysubstituted tetrahydro-1,6-naphthyridine scaffolds.

The Impact of Socio-Cultural Differences on Educational Values: A Comparison of the Pedagogy of Michael Oakeshott and John McGahern

Science.gov (United States)

Williams, Kevin

2017-01-01

The year 2016 marked the tenth anniversary of the death of John McGahern (born 1934), the widely acclaimed Irish author. There is a shared temper of mind and several common strands in the work of McGahern and that of the English philosopher, Michael Oakeshott (1900-1990). Despite the very different cultural environments in which they grew up and…

Reaction of North American neo-Thomism against the «Intelligent Design»

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Desiderio Parrilla Martínez

2017-08-01

Full Text Available The doctrine of «Intelligent Design» formulated by Phillip E. Johnson, Michael Behe, William A. Dembski and Stephen C. Meyer is presented as a scientific alternative to neo-Darwinism. For philosophical naturalism or atheism is only a pseudo-science dependent of «Protestant creationism» and the literal biblical interpretation. The best philosophical critiques, however, come from American neo-Thomism. This paper presents the main arguments used by the Thomism in his polemic against the doctrine of «Intelligent Design».

El movimiento como simulacro en el mundo virtual: Michael Betancourt y el arte de la inmediatez. = Movement as simulacrum in the virtual world: Michael Betancourt and the art of immediacy

Directory of Open Access Journals (Sweden)

José Manuel García Perera

2016-05-01

Full Text Available La creación artística se ha acercado en los últimos tiempos a la imagen mediática que propone Internet, alterando sustancialmente una experiencia estética antes basada en el movimiento del espectador en torno a la obra y definida ahora por pantallas que inducen a la pasividad. El trabajo en vídeo de Michael Betancourt, encuadrado en el denominado arte glitch, ese que se fija en el fallo ocurrido dentro del ámbito digital, ha sido la base para realizar aquí un estudio comparativo entre diferentes concepciones artísticas del movimiento, así como entre un arte pasado y otro actual que permite ver cómo los avances tecnológicos han originado cambios radicales en la naturaleza corpórea, espacial y móvil de la obra. La investigación de Betancourt propone un nuevo arte cinético que, por medio del error, se hace crítico, se mimetiza con el movimiento en tiempo real que la contemporaneidad demanda y destapa el artificio de imágenes que imitan a la realidad como si quisieran sustituirla.In recent times, artistic creation has come closer to the media image proposed by Internet, thus seriously altering an aesthetic experience based before on movement of the viewer around the work and now defined by screens that induce passivity. Michael Betancourt’s video work, part of the so-called glitch art, which focuses on the failure that can occur within the digital realm, has been here the basis for a comparative study between different concepts of movement in art, as well as between a current and a past art, a comparison that allows us to see clearly how technological advances have produced radical changes in the physical, spatial and mobile nature of the artwork. Betancourt’s investigation proposes a new kinetic art that becomes critical through error, mimics the real-time movement that contemporary culture demands, and uncovers the artificiality of images that mimic reality as if they wanted to replace it.

‘Introducing Michael Gove to Loïc Wacquant’: Why Social Work Needs Critical Sociology

Science.gov (United States)

Michael Garrett, Paul

2016-01-01

In 2013, Michael Gove, then Secretary of State for Education and Health in the UK coalition government, criticised social workers for laying insufficient emphasis on the ‘agency’ of individuals and for being too preoccupied with social and economic inequalities. Such a perspective, which is not unique to Gove, needs to be countered by reaffirming the significance of an expansively critical sociology for social work. In this context, the thematic concerns of the French theorist, Loïc Wacquant, illuminates key aspects of social work engagement with clients which Gove and his ideological associates appear intent on ignoring. The issues raised have significant political resonances given the pending UK General Election taking place in May 2015. PMID:27559203

QCD propagators and vertices from lattice QCD (in memory of Michael Müller-Preußker

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Sternbeck André

2017-01-01

Full Text Available We review lattice calculations of the elementary Greens functions of QCD with a special emphasis on the Landau gauge. These lattice results have been of interest to continuum approaches to QCD over the past 20 years. They are used as reference for Dyson-Schwinger- and functional renormalization group equation calculations as well as for hadronic bound state equations. The lattice provides low-energy data for propagators and three-point vertices in Landau gauge at zero and finite temperature even including dynamical fermions. We summarize Michael Müller-Preußker’s important contributions to this field and put them into the perspective of his other research interests.

Review Article: Yamada, Jeni "Laura: A Case for the Modularity of Language"; Tomasello, Michael "First Verbs: A Case Study of Early Grammatical Development."

Science.gov (United States)

Shatz, Marilyn

1994-01-01

Jeni Yamada's "Laura" and Michael Tomasello's "First Verbs" continue a tradition of providing useful information on the language ability of individuals in a depth rarely found in multisubject studies; however, these efforts are unusual for case studies in that both take strong theoretical positions on the essence of language and language learning.…

Stereoselective synthesis of 5-alkoxycarbonyl-4 alkyl-2-anino-3-cyano-6-methyl-4H-pyranes 3 via asymmetric Michael addition to aceptors-gamma-stereogenics; Sintesis esteroselective de 5-alcoxicarbonil-4-alquil-2-amino-3-ciano-6-metil-4H-piranos via adicion Michael sobre aceptores-gama-esterogenicos

Energy Technology Data Exchange (ETDEWEB)

Martinez-Grau, A.; Jimenez, B.; Martin, N.; Seoane, C.; Marco, J.L. [Departamento de Quimica Organica, Facultad de Quimica, Universidad Complutense, Madrid (Spain)

1994-12-31

The stereoselective synthesis of 5-alkoxycarbonyl-4-alkyl-2-amino-3-cyano-6-methyl-4H-pyrans 3 via asymmetric Michael addition of malononitrile to gamma-stereogenic alpha-acetylacrylates 2 obtained by Knoevenagel reaction of acetylacetates to quiral alpha-hydroxyaldehydes 1 is described. The resulting 2-amino-4H-pyrans 3 have been obtained in moderate yield and good diastereoselectivity. 15 refs.

Synthesis of some pyridine and pyrimidine derivatives via Michael-Addition

International Nuclear Information System (INIS)

El-Baih, Fatma E.M.; Al-Rasheed, Hessa H.; Al-Hazimi, Hassan M.

2006-01-01

Synthesis of pyridine and pyrimidine analogues 4 and 6-9 were achieved by Michael-addition of compounds containing either active methylene groups like, malononitrile , ethyl cyanoacetate and 1-tetralone or compounds containing active hydrogen atoms like, guanidine in the presence of an oxidizing agent and thiourea to 2-arylmethylidine-1-tetralone and 2-arylmethylidine-6-methoxy-1-tetralone (2) (enones). Addition of malononitrile in piperidine at room temperature to 2-amino-3-cyno-naphtho [1, 2-malonoitrile in sodium alkoxide or sodium hydroxide to 2 gave 4. Cyclization of 3a with acetic anhydride in the presence of conc. H2sO4 gave the naphtha-pyrano[2, 3-d]pyrimidin-8-one (5). Condensation of the pyrimidine thione derivatives 9 with chloroacetic acid gave the 3-oxobenzo[h]thiazoladino[2, 3-b]quinazoline derivatives (10), which were reacted through their active methylene groups with aromatic aldehydes to give the arylidine derivatives 11. These compounds were also prepared in one step by reacting 9 with chloroacetic acid and aromatic aldehydes. Condensation of 9 with 3-bromopropanoic acid gave 4-oxo-benzo[h]1, 3-thiazino[2, 3-b]quinazoline derivatives (12). The structures of the prepared compounds were mainly confirmed on the basis of spectroscopic methods. (author)

Michael additions of thiocompounds to {alpha}, {beta}-unsaturated carbonyl compounds in aqueous media: stereoselectivity with unambiguous characterization by NMR

Energy Technology Data Exchange (ETDEWEB)

Almeida, Queli Aparecida Rodrigues de; Pereira, Maria Luiza de Oliveira; Coelho, Ricardo Bezerra; Kaiser, Carlos Roland; Jones Junior, Joel; Silva, Flavia Martins da [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Inst. de Quimica. Dept. de Quimica Organica]. E-mail: soa@iq.ufrj.br; Carvalho, Erika Martins de [Instituto de Tecnologia em Farmacos (Far-Manguinhos), Rio de Janeiro, RJ (Brazil)

2008-07-01

The reactions of crotonaldehyde (8) with thiophenol (2) and benzalacetone (10) with ethane-1,2- dithiol (11) yield Michael addition products. The reactions of thiophenol (2) with (R)-carvone (13) and (S)-perillaldehyde (15) lead to (2S,3R,5S)-5-isopropenyl-2-methyl-3-(phenylthio)cyclohexanone (14) and (1R,2R,4S)-4-isopropenyl-2-(phenylthio)cyclohexanecarbaldehyde (16), respectively. An unambiguous elucidation of the stereochemistry of 14 and 16 by NMR is also presented. (author)

Infant feeding practices during the first 6 months of life in a low ...

African Journals Online (AJOL)

Qualitative findings indicated that gripe water, Lennon's Behoedmiddel and herbal medicines were also given to infants. Nutritive liquids and/or food most commonly given as supplementary feeds were formula milk and commercial infant cereal. Conclusion. Exclusive breastfeeding (EBF) during the first 6 months of life was ...

Nano-organocatalyst: magnetically retrievable ferrite-anchored glutathione for microwave-assisted Paal–Knorr reaction, aza-Michael addition, and pyrazole synthesis

KAUST Repository

Polshettiwar, Vivek; Varma, Rajender S.

2010-01-01

Postsynthetic Surface modification of magnetic nanoparticles by glutathione imparts desirable chemical functionality and enables the generation of catalytic sites on the surfaces of ensuing organocatalysts. In this article, we discuss the developments, unique activity, and high selectivity of nano-organocatalysts for microwave-assisted Paal-Knorr reaction, aza-Michael addition, and pyrazole synthesis. Their insoluble character Coupled with paramagnetic nature enables easy separation of these nano-catalysts from the reaction mixture using external magnet, which eliminates the requirement of catalyst filtration. Published by Elsevier Ltd.

A designated centre for people with disabilities operated by St Michael's House, Dublin 11

LENUS (Irish Health Repository)

Abu, Ozotu Rosemary

2016-08-01

This mixed method research explores unprofessional behaviour experienced by clinical Medical students, during clinical training in Ireland; with a view to obtaining learning points that inform future design of modules on Professionalism. It also looks at the impact of these on students and the relationship between gender\\/ethnicity and students’ experiences of these behaviours.

Cuestión de tiempo: Michael Fried y el tiempo del arte moderno A matter of time: Michael Fried and modernist art the time of modernist art

Directory of Open Access Journals (Sweden)

David Díaz Soto

2011-07-01

Full Text Available En el siglo XIX, autores fundacionales del formalismo, como Fiedler o Hildebrand, contrapusieron estrictamente las artes plásticas, «puramente visuales», a las artes verbales del discurso, proscribiéndoles la narración y disociándolas de la temporalidad: se trata del «principio de exclusión del tiempo», vinculado al formalismo. Más tarde, el crítico «modernista» de arte Clement Greenberg planteó la instantaneidad, en tanto que opuesta a la duración, como modalidad ideal de la experiencia artística. Pero el historiador y crítico de arte Michael Fried, en sus textos de los años 60 sobre arte abstracto, se distancia de Greenberg, desarrollando un discurso sobre la temporalidad en las artes plásticas, con nociones como «tiempo visual»; y en sus posteriores textos historiográficos investiga las modalidades temporales de la representación pictórica. La aparente paradoja entre la crítica de Fried a la hipóstasis «literalista» de la duración en las tardovanguardias y el papel crucial que concede a Manet y a la instantaneidad en el origen del arte moderno, la resolveremos atendiendo a su reivindicación de la temporalidad durativa de «lo cotidiano». Así cabe comprender la concepción de la modalidad temporal característica de la modernidad y del arte moderno, a la que apunta su noción teórica de presentness.In the nineteenth century, seminal authors of Formalism, like Fiedler or Hildebrand, strictly compared the «purely visual» plastic arts to the discursive arts of verbal language, ruling out narrativity from plastic arts, which they dissociated from temporality - the formalist «principle of exclusion of time». Later on, «modernist» art critic Clement Greenberg claimed that instantaneousness, as opposed to duration, was the ideal modality for artistic experience. Art critic and historian Michael Fried did not share Greenberg's position, but developed instead a discourse about time in plastic arts. In his early

‘Doxographical or Philosophical History of Philosophy: On Michael Frede’s Precepts for Writing the History of Philosophy’

DEFF Research Database (Denmark)

Catana, Leo

2016-01-01

In a series of articles from the 1980s and 1990s, Michael Frede analysed the history of histories of philosophy written over the last three hundred years. According to Frede, modern scholars have degenerated into what he calls a “doxographical” mode of writing the history of philosophy. Instead, he...... argued, these scholars should write what he called “philosophical” history of philosophy, first established in the last decades of the seventeenth century but since abandoned. In the present article it is argued that Frede’s reconstruction of the history of histories of philosophy is historically...

How "The Right" Continues to "Do Wrong" by Our Young People: Contemporary Reflections on Michael Apple's Analysis of the "Rightist Turn" in Education

Science.gov (United States)

McGregor, Glenda

2018-01-01

Michael Apple's 2005 article, "Doing Things the 'Right' Way: Legitimating Educational Inequalities in Conservative Times", is a seminal piece of writing that highlights some of his core concerns with the effects of neo-liberal and neo-conservative ideologies on education. Since its publication, this article has incited much debate about…

Multicomponent Synthesis of Isoindolinone Frameworks via RhIII -Catalysed in situ Directing Group-Assisted Tandem Oxidative Olefination/Michael Addition.

Science.gov (United States)

Wang, Liang; Liu, Xi; Liu, Jian-Biao; Shen, Jun; Chen, Qun; He, Ming-Yang

2018-04-04

A Rh III -catalysed three-component synthesis of isoindolinone frameworks via direct assembly of benzoyl chlorides, o-aminophenols and activated alkenes has been developed. The process involves in situ generation of o-aminophenol (OAP)-based bidentate directing group (DG), Rh III -catalysed tandem ortho C-H olefination and subsequent cyclization via aza-Michael addition. This protocol exhibits good chemoselectivity and functional group tolerance. Computational studies showed that the presence of hydroxyl group on the N-aryl ring could enhance the chemoselectivity of the reaction. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Het verband tussen geluk, wijsheid, Twitter en Serendipity

NARCIS (Netherlands)

drs. Frans van den Reep

2012-01-01

1e alinea column: Life happens to you while you are busy making other plans, J. Lennon Hoe komen succesvolle innovaties in de internettijd tot stand? Toeval, geluk, reputatie en timing blijven een rol spelen, maar social media en 24*7 wereldwijd verbonden maken het spel wel anders dan vroeger.

WHEN DYLAN MET THE BARD: TRANSLATING HAMLET FROM TEXT TO SCREEN (SOUND: MICHAEL ALMEREYDA’S HAMLET

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Marina Gerzic

2015-12-01

Full Text Available Director Michael Almereyda’s diverse musical choices in the film are a threshold into understanding his cinematic interpretation of Hamlet (2000. Almereyda recontextualises Hamlet in terms of contemporary social problems. Hamlet and Ophelia are confronted with and battle against urban claustrophobia, conspiracy and global corporate power. A fragment of the Bob Dylan song ‘All Along the Watchtower’ (1966 is used as a filmic shortcut to translate Shakespeare’s iconic ‘gravedigger scene’ between Hamlet and the Gravedigger from playtext to screen. ‘All Along the Watchtower’ encapsulates certain ideas about mortality and the worth of life from the ‘gravedigger scene’ and demonstrates these issues still resonate in the contemporary urban world the film is set.

A History of Experiences and Thinking Men. The History of Political Thought according to Michael Oakeshott

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Spartaco Pupo

2014-12-01

Full Text Available Michael Oakeshott conceives the history of European political thought as a structuring of ideas and arguments of the practical experience aimed to understanding political expressions in vogue in the culture of a people. It is not a continuous and cumulative history of abstract and disembodied ideas, as it is wrongly conceived, but of some men who thought politics in a certain way on the basis of the language and of the set of actions, moral beliefs and contingencies of the people which they belong to. The article highlights the comparison between Oakeshott, Quentin Skinner and Gianfranco Miglio on the search for the most appropriate method to be applied in the study of the history of political thought.

Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens

Czech Academy of Sciences Publication Activity Database

Götz, M. G.; James, K. E.; Hansell, E.; Dvořák, J.; Seshaadri, A.; Sojka, Daniel; Kopáček, Petr; McKerrow, J. H.; Caffrey, C. R.; Powers, J. C.

2008-01-01

Roč. 51, č. 9 (2008), s. 2816-2832 ISSN 0022-2623 R&D Projects: GA MŠk(CZ) LC06009; GA ČR GA206/06/0865 Grant - others:The National Institute of Allergy and Infectious Diseases(US) AI053247; National Institute of General Medical Sciences(US) GM54404; National Institute of General Medical Sciences(US) GM61964 Institutional research plan: CEZ:AV0Z60220518 Keywords : legumain * IrAE * aza-peptide Michael acceptors Subject RIV: ED - Physiology Impact factor: 4.898, year: 2008

One-Pot Synthesis of 2-Acylindole-3-acetylketones via Domino Aza-alkylation/Michael Reaction Using o-Aminophenyl α,β-Unsaturated Ketones Followed by Desulfonative Dehydrogenation

Energy Technology Data Exchange (ETDEWEB)

Kim, A Reum; Yu, Mi Rim; Sim, Jong Tack; Kim, Sung Gon [Kyonggi Univ., Suwon (Korea, Republic of)

2016-09-15

The development of novel and practical synthetic methods with a minimum number of operations for the construction of bioactive structurally complex compounds is a major challenge in synthetic organic chemistry. Recently, we reported an efficient method for the stereoselective synthesis of 2,3-disubstituted indoline derivatives; cis-2,3-disubstituted indolines were obtained by the aza-alkylation/Michael cascade reaction of 2-(tosylamino)phenyl α,β-unsaturated ketones with α-bromoacetophenones in good yields and with excellent diastereoselectivities (Scheme 2, Eq. (1)). Among the available synthetic strategies, domino or cascade reactions have received wide acceptance as highly efficient and powerful methods for the synthesis of molecules with a high structural complexity. An efficient synthesis of 2,3-disubstituted indoles was developed by the domino aza-alkylation/intramolecular Michael reaction of 2-(tosylamino)phenyl α,β-unsaturated ketones with α-bromoacetophenones, followed by desulfonative dehydrogenation with DBU. The reaction afforded structurally diverse and highly functionalized 2,3-disubstituted indoles in moderate to excellent yields (up to 99%). The synthesis of 2,3-disubstituted indoles without desulfonation through DDQ-induced oxidative dehydrogenation was also achieved.

On Politics and Education Finance: A Bibliography of Joel S. Berke, James W. Guthrie, and Michael W. Kirst. Vance Bibliographies, Public Administration Series: Bibliography P-821.

Science.gov (United States)

Quay, Richard H.

A bibliography of Joel S. Berke, James W. Guthrie, and Michael W. Kirst on politics and educational finance is presented. Specific topics include the following: whether financial support of public schools should be assumed completely by states, school finance policies and practices, school finance reform versus the spending and tax limitation…

Evaluation Strategy Michael Porter's five forces model of the competitive environment on the dairy industry (Case Study: Amoll Haraz Dvshh dairy company)

OpenAIRE

Mohammad Bolorian Tehrani; Faezeh Rahmani

2016-01-01

State of competition in an industry depends on five basic forces. Porter's five forces model including bargaining power of customers, bargaining power of suppliers, threat of newcomers to the industry, threat of substitute products is the intensity of rivalry between competitors. Joint strength of these forces determines the ultimate benefit of potentially any industry. The purpose of this study was to evaluate the competitive environment of the dairy industry based on Michael Por...

Tim Burton lavastab Batmani muusikali. Placido Domingo palkas "Star Warsi" võluri. MTV muusikaauhindade show'l narriti Michael Jacksonit. Hendrixi põlenud kitarr läheb müüki

Index Scriptorium Estoniae

2002-01-01

Jim Steinman kirjutab muusikat Tim Burtoni 2005. aastal lavale tulevale Batmani muusikalile. Los Angelese ooperimaja juht Domingo palkas George Lucase Wagneri ooperi "Nibelungide sõrmus" eriefektide ettevalmistamiseks. Britney Spears nimetas Michael Jacksonit Millenniumi artistiks.

Cadrage, décadrage et recadrage dans Baa Baa Black Sheep : A Jungle Tale de David Malouf et Michael Berkeley Patrimonial Deconstruction and Reconstruction in David Malouf and Michael Berkeley’s Baa Baa Black Sheep : A Jungle Tale

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Jean-Philippe Héberlé

2011-11-01

Full Text Available This article discusses Michael Berkeley’s first opera, Baa Baa Black Sheep: A Jungle Tale. Premiered under the baton of Paul Daniel on July 3rd 1993 at the Cheltenham International Festival of Music, this opera is based on two texts by Rudyard Kipling: The Jungle Books (1894-1895 and “Baa, Baa, Black Sheep” from the short story collection Wee Willie Winkie and Other Stories, first published in 1888. The libretto was penned by the Australian poet, novelist, playwright and librettist, David Malouf. After a brief survey of some of the earliest transpositions of The Jungle Books, I analyse the way David Malouf deals with both texts. “Baa Baa Black Sheep” is used as the central element of his libretto, and episodes and characters from The Jungle Books are incorporated to draw parallelism between the main topics of the two texts. Both Malouf’s endeavour and Berkeley’s, through the music, aims at deconstructing the preposterous oldest transpositions of The Jungle Books and at focusing on the key elements of Kipling’s famous book, notably identity and hybridism, two important themes of colonial and postcolonial literature. The aim of David Malouf and Michael Berkeley is to address an adult audience and show that The Jungle Books are not only aimed at children as Disney’s or Baden Powell’s appropriations of the work could wrongly make us believe.Cet article porte sur Baa Baa Black Sheep: A Jungle Tale, le premier opéra de Michael Berkeley. Créé au Everyman Theatre de Cheltenham le 3 juillet 1993 sous la direction de Paul Daniel, cette œuvre est le fruit de la collaboration entre le compositeur britannique et l’écrivain australien David Malouf. Le livret de Malouf se fonde sur deux récits de Rudyard Kipling : la nouvelle autobiographique “Baa, Baa, Black Sheep” auquel l’opéra doit son nom et The Jungle Books. Après m’être intéressé aux premières transpositions musicales de The Jungle books, je montre comment

"Beatlemania" in the General Music Classroom

Science.gov (United States)

Cardany, Audrey Berger

2012-01-01

In Geoff Edgers's biography of the Beatles, "Who Were the Beatles?", young readers learn of John Lennon, Paul McCartney, Ringo Starr, and George Harrison's youth and growth as musicians, the band's formation, and their contributions to music in popular culture. "General Music Today" columnist, Cardany provides music teachers with related music…

Mandibular angle augmentation with the use of distraction and homologous lyophilized cartilage in a case of morphing to Michael Jackson surgery.

Science.gov (United States)

Mommaerts, M Y; Abeloos, J S; Gropp, H

2001-08-01

Correction of an ill-defined mandibular angle is not an easy task, whether it is requested by the "congenital, orthognathic or cosmetic" patient. Deliberate over-correction has not been reported to our knowledge. This article presents a combination of distraction osteogenesis and lyophilized cartilage used to three-dimensionally over-augment the mandibular angle of a long-face prognathic patient who had the wish to be morphed to Michael Jackson or at least as far as current technique and his endogenic features allowed.

Revisitando a Teoria da Guerra Justa: uma análise das propostas de Michael Walzer e Jeff McMahan

OpenAIRE

Cruz, Sara Vieira

2015-01-01

Dissertação de mestrado em Filosofia Política O propósito desta dissertação é fornecer uma compreensão panorâmica das principais questões morais suscitadas pela guerra, com uma ênfase especial na guerra moderna e no debate académico contemporâneo. Partindo da visão tradicional da Teoria da Guerra Justa defendida por Michael Walzer, focamo-nos essencialmente na tensão existente entre este teórico e o seu principal oponente, Jeff McMahan. Em causa está a sustentabilidade do pa...

Kochin, Michael S. 2009. Five Chapters on Rhetoric: Character, Action, Things, Nothing and Art (University Park: Pennsylvania State University Press

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Eithan Orkibi

2010-04-01

Full Text Available Deux constatations traversent le nouvel ouvrage de Michael Kochin, et nous invitent à reconsidérer la rhétorique dans la communication persuasive. D’abord, que ce sont les événements concrets et les faits mis à l’épreuve qui ont la plus grande force de conviction ; et ensuite, que le discours a souvent une fonction autre que la persuasion : celle de maintenir les canaux de communication pour sauvegarder les relations et les institutions humaines. Pour l’auteur de cet ouvrage qui porte sur les...

Beyond the center: Sciences in Central and Eastern Europe and their histories. An interview with professor Michael Jordan conducted by Jan Surman

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Michael Gordin

2016-11-01

Full Text Available What is special about sciences in Central and Eastern Europe? What are the obstacles for writing histories of science done beyond metropoles? Is this science different than the science in the centers and what makes it so? How imperial are sciences made by representatives of dominant nations compared to non-dominant nations? These are some of the questions touched upon in the interview with Michael Gordin, a leading historian of science from Princeton University.

Losing Touch: A Theology of Death for Michael Haneke’s Amour

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Taylor Worley

2016-11-01

Full Text Available This proposed theology of death for Michael Haneke’s Amour, a fraught but poignant piece of cinema, will employ Martin Heidegger’s existentialism to reframe the ethical structure of the film and apply a “lived theology” rejoinder to its perceived hopelessness. The proposal will address the question of ethics in relation to Haneke’s cinema, in particular his seemingly nihilistic perspective and confrontational style. To do so, it will revisit the film itself and examine the ways that Georges and Anne’s love is tested. Principally, we examine the film’s great question, which—in the filmmaker’s own words—is: “How do I cope with the suffering of a loved one?” With aid from the theologian Dietrich Bonhoeffer, this ‘lived theology’ proposal will attempt to give an account of love’s irrepressible strength in the midst of even astounding suffering. While Heidegger’s ethic of resoluteness calls for interiority and solitude, Bonhoeffer’s account of death more satisfactorily invokes a transcendent summons contained within our own pledges to loved ones. Such a theological reading of Haneke’s Amour will draw two distinct conclusions: first, the film exposes the superficiality of any hoped-for solitude or escape from a loved one’s death, and secondly, it demonstrates that the mutuality of authentic love entails impossible sacrifices.

Analysis of the Competitive Potential of Bioethanol in Colombia: An approach from Michael Porter's 5 Competitive Forces

International Nuclear Information System (INIS)

Ramirez Velasquez, Alejandro; Montoya R, Ivan Alonso; Montoya Restrepo, Alexandra

2012-01-01

The search for alternative energy production and consumption require a look into the industry of biofuels such as bioethanol as an alternative energy to overcome the disadvantages generated by the traditional methods of production and consumption, especially in the political, environmental and social issues and generate competitive advantages compared to other primary energy sources. In the present document, and from the Michael Porter five (5) Forces model is detailed an evaluation of the bioethanol industry as an alternative fuel and is described how attractive or competitive may become the industry today. To achieve this purpose, an evaluation of the competitive forces was proposed to a group of experts, using a Likert scale. Thus, it was evaluated the potential usefulness of the proposal.

La théorie sémiotique littéraire de Michael Riffaterre : matrice, intertexte et interprétant

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John Hopkins

2005-04-01

Full Text Available Cette communication présentée lors d’un séminaire du CNA, présente une vision de la théorie littéraire de Michael Riffaterre et propose d’en compléter la portée par un apport théorique nouveau. La dernière partie examine les rapports de la théorie riffaterrienne avec le roman. Sémiotique, poésie, matrice, structure bimatricielle, Riffaterre, Baudelaire. Puisque je parle aux confins du Centre de Narratologie Appliquée, où l’on s’intéresse principalement aux questions de la structure et de...

VizieR Online Data Catalog: Hα and [NII] survey in local 11 Mpc (Kennicutt+, 2008)

Science.gov (United States)

Kennicutt, R. C. Jr; Lee, J. C.; Funes, J. G.; Sakai, S.; Akiyama, S.

2009-11-01

Most of the Hα and R imaging reported in this paper was obtained in 2001-2004 using CCD direct imagers on the Steward Observatory Bok 2.3m telescope on Kitt Peak (Bok), the Lennon 1.8m Vatican Advanced Technology Telescope (VATT), and the 0.9m telescope at Cerro Tololo Interamerican Observatory (CTIO). (3 data files).

The economic role of the Emergency Department in the health care continuum: applying Michael Porter's five forces model to Emergency Medicine.

Science.gov (United States)

Pines, Jesse M

2006-05-01

Emergency Medicine plays a vital role in the health care continuum in the United States. Michael Porters' five forces model of industry analysis provides an insight into the economics of emergency care by showing how the forces of supplier power, buyer power, threat of substitution, barriers to entry, and internal rivalry affect Emergency Medicine. Illustrating these relationships provides a view into the complexities of the emergency care industry and offers opportunities for Emergency Departments, groups of physicians, and the individual emergency physician to maximize the relationship with other market players.

A designated centre for people with disabilities operated by St Michael's House, Co. Dublin

LENUS (Irish Health Repository)

MacFarlane, Anne

2011-11-19

Abstract Background Implementation researchers have attempted to overcome the research-practice gap in e-health by developing tools that summarize and synthesize research evidence of factors that impede or facilitate implementation of innovation in healthcare settings. The e-Health Implementation Toolkit (e-HIT) is an example of such a tool that was designed within the context of the United Kingdom National Health Service to promote implementation of e-health services. Its utility in international settings is unknown. Methods We conducted a qualitative evaluation of the e-HIT in use across four countries--Finland, Norway, Scotland, and Sweden. Data were generated using a combination of interview approaches (n = 22) to document e-HIT users\\' experiences of the tool to guide decision making about the selection of e-health pilot services and to monitor their progress over time. Results e-HIT users evaluated the tool positively in terms of its scope to organize and enhance their critical thinking about their implementation work and, importantly, to facilitate discussion between those involved in that work. It was easy to use in either its paper- or web-based format, and its visual elements were positively received. There were some minor criticisms of the e-HIT with some suggestions for content changes and comments about its design as a generic tool (rather than specific to sites and e-health services). However, overall, e-HIT users considered it to be a highly workable tool that they found useful, which they would use again, and which they would recommend to other e-health implementers. Conclusion The use of the e-HIT is feasible and acceptable in a range of international contexts by a range of professionals for a range of different e-health systems.

La figura del libro in Die unendliche Geschichte di Michael Ende: da finestra a varco

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Elena Di Cesare

2015-01-01

Full Text Available The book is an object which can be considered as a window in the novel Die unendliche Geschichte (1979 written by Michael Ende. It allows Bastian to look at the world of Phantasien and to communicate indirectly with the Childlike Empress. Furthermore, this object will show its function as an symbol of evolution, which will enable the passage of the protagonist into the world of Phantasien: first the book appears as a window, then it becomes a two-way-mirror that allows Bastian and Atreju to look at each other, and finally it turns into a gate which enables them to live many adventures together. Die unendliche Geschichte can be considered as a modern Bildungsroman in which the young protagonist gradually reaches his maturation. This progress must be seen in a psychological perspective: it is the growth of a child-mind through literature which makes reference to the German novel tradition but also (as children’s literature to the world of unconsciousness.

Novel Interecting Blends Based on Amino Terminited Oligoimides by Using Michael Addition Reaction-II

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Rita R. Patel

2012-01-01

Full Text Available New amino terminated oligoimides (AOIs were prepared by the Michael addition reaction of various bismaleimide (1, namely, 1-(4-((4-((2, 5-dioxocyclopent-3 enylamino methyl cyclohexyl methyl cyclohexyl-1, 6-dihydropyridine-2, 5-dione with excess of various diamines (2a-c. These AOIs were characterized by elemental analysis, FT-IR spectral studies and number average molecular weight estimated by non-aqueous conductometric titrations. AOIs were then treated with acrylol chloride and resultant acryl terminated oligoimides (AcOIs samples were also characterized thermogravimetrically. Each of these AcOI was then combined with the N-phenyl maleimide (PM in THF solvent. The resultant suspensions were then heated in the presence of azobisisobutyronitrile (AIBN as an initiator. The AcOI and PM polymerized through double bond simultaneously and form interacting blends, which were analyzed thermogravimetrically. The glass fiber reinforced composites were fabricated by using the suspensions of the AcOI and PM. The composites of Interacting blends were analyzed for their mechanical, chemical and electrical properties.

Switchable Diastereoselectivity in the Fluoride Promoted Vinylogous Mukaiyama-Michael Reaction of 2-Trimethylsilyloxyfuran Catalyzed by Crown Ethers

KAUST Repository

Della Sala, Giorgio

2017-05-31

The fluoride promoted vinylogous Mukaiyama-Michael reaction (VMMR) of 2-trimethylsilyloxyfuran with diverse α,β-unsaturated ketones is described. The TBAF catalyzed VMMR afforded high anti-diastereoselectivity irrespective of the solvents used. The KF/crown ethers catalytic systems proved to be highly efficient in terms of yields and resulted in a highly diastereoselective unprecedented solvent/catalyst switchable reaction. Anti-adducts were obtained as single diastereomers or with excellent diastereoselectivities when benzo-15-crown-5 in CH2Cl2 was employed. On the other hand, high syn-diastereoselectivities (from 76:24 to 96:4) were achieved by employing dicyclohexane-18-crown-6 in toluene. Based on DFT calculations, the catalysts/solvents-dependent switchable diastereoselectivities are proposed to be the result of loose or tight cation-dienolate ion pairs.

Integral Sustainable Design: Transformative Perspectives (by M. DeKay (Ed. with S. Bennett, 2011

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Michael Schwartz

2013-02-01

Full Text Available Reviewed by Michael Schwartz Mark DeKay, Professor of Architecture and Director of Graduate Studies in the College of Architecture at the University of Tennessee, a prominent scholar-practitioner in the field of sustainable design, opens his latest book with the explicit intention that the volume “help create a breakthrough in the effectiveness of the Sustainable Design movement such that it is transformed to greater power, relevance, meaning and positive effect on people and Nature” (p. xxi. His approach is thoroughly integral, taking up Wilber’s classic integral theory, more or less a version of “Wilber-4,” clarifying and extending this meta-theory in service of creating and advancing sustainable design as discipline and practice.

Selective bird predation on the peppered moth: the last experiment of Michael Majerus.

Science.gov (United States)

Cook, L M; Grant, B S; Saccheri, I J; Mallet, J

2012-08-23

Colour variation in the peppered moth Biston betularia was long accepted to be under strong natural selection. Melanics were believed to be fitter than pale morphs because of lower predation at daytime resting sites on dark, sooty bark. Melanics became common during the industrial revolution, but since 1970 there has been a rapid reversal, assumed to have been caused by predators selecting against melanics resting on today's less sooty bark. Recently, these classical explanations of melanism were attacked, and there has been general scepticism about birds as selective agents. Experiments and observations were accordingly carried out by Michael Majerus to address perceived weaknesses of earlier work. Unfortunately, he did not live to publish the results, which are analysed and presented here by the authors. Majerus released 4864 moths in his six-year experiment, the largest ever attempted for any similar study. There was strong differential bird predation against melanic peppered moths. Daily selection against melanics (s ≈ 0.1) was sufficient in magnitude and direction to explain the recent rapid decline of melanism in post-industrial Britain. These data provide the most direct evidence yet to implicate camouflage and bird predation as the overriding explanation for the rise and fall of melanism in moths.

A man and his island: The island mirror in Michael Crummey’s Sweetland

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Laurie Brinklow

2016-05-01

Full Text Available Between 1946 and 1975, dozens of islands and outports in the Canadian province of Newfoundland and Labrador were abandoned as part of a government resettlement policy. Families and communities were torn apart, and a culture and way of life that revolved around the fishery changed irrevocably. The practice, which continues to this day, has been well documented, particularly by artists and writers. Michael Crummey’s 2014 novel Sweetland is a recent iteration. The relationship between humans and place is complex: on an island, with compressed space and a very real boundary that is the ocean, emotional attachments to one’s place are often heightened and distilled. What happens when a person is displaced from his or her island; when bonds of attachment are severed and one’s mirrored double is destroyed? Sweetland offers a fictional lens through which we see an example of a mirrored relationship between an island protagonist and his island setting. Exploring themes of attachment to place, and what Barry Lopez calls a “storied” or “reciprocal” relationship with the land, this paper examines what happens to a man when confronted with leaving an island he knows as deeply as his own body and soul; and how the island reacts.

Michael Jackson, Bin Laden and I: functions of positive and negative, public and private flashbulb memories.

Science.gov (United States)

Demiray, Burcu; Freund, Alexandra M

2015-01-01

This study examined the perceived psychosocial functions of flashbulb memories: It compared positive and negative public flashbulb memories (positive: Bin Laden's death, negative: Michael Jackson's death) with private ones (positive: pregnancy, negative: death of a loved one). A sample of n = 389 young and n = 176 middle-aged adults answered canonical category questions used to identify flashbulb memories and rated the personal significance, the psychological temporal distance, and the functions of each memory (i.e., self-continuity, social-boding, directive functions). Hierarchical regressions showed that, in general, private memories were rated more functional than public memories. Positive and negative private memories were comparable in self-continuity and directionality, but the positive private memory more strongly served social functions. In line with the positivity bias in autobiographical memory, positive flashbulb memories felt psychologically closer than negative ones. Finally, middle-aged adults rated their memories as less functional regarding self-continuity and social-bonding than young adults. Results are discussed regarding the tripartite model of autobiographical memory functions.

Universal Alienation, Formal and Real Subsumption of Society Under Capital, Ongoing Primitive Accumulation by Dispossession: Reflections on the Marx@200-Contributions by David Harvey and Michael Hardt/Toni Negri

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Christian Fuchs

2018-05-01

Full Text Available This contribution presents reflections on the contributions of and the debate between David Harvey and Michael Hardt/Toni Negri that we feature as the opening part of the tripleC-special issue “Marx@200: Debating Capitalism & Perspectives for the Future of Radical Theory”. My reflection contextualises the debate by a discussing the origin and genesis of Marx’s concepts of alienation, formal/real subsumption, and primitive accumulation and b situating the arguments in earlier works by Harvey, Hardt and Negri. This paper points out differences as well as the strong commonalities between the works of Michael Hardt/Toni Negri and David Harvey. It discusses how the categories of universal alienation, formal/real subsumption of society under capital, original/ongoing primitive accumulation of capital are related. Harvey and Hardt/Negri show that Marx’s theory and politics are alive 200 years after his birth and will haunt capitalism as long as it exists. The paper concludes by arguing that Harvey’s concept of anti-value and the autonomous notion of self-valorisation point towards democratic, commons-based alternatives to capitalism.

Corrupting Capitalism: Michael Ende’s Momo and “Cathedral Station”

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Heike Polster

2016-01-01

Full Text Available Michael Ende, the well-known author of The Neverending Story , foresaw dramatic changes in the fabric of society resulting from a turn toward neoliberal policies. One such far-reaching and dangerous change has to do with a diminishing of temporal autonomy, the ability to freely determine the use and meaning of our time. This article explores how neoliberalism is shaping our concept of time and our experience of it. In an effort to demonstrate the process and the line of reasoning behind the monetization of time, and to connect time to more qualitative considerations of the human condition, I shall demonstrate how Ende conceptualizes time as an integral part of the accumulation process of capitalism. I also discuss a fairly cryptic short story, “Cathedral Station,” that envisions “the mystery of money.” Utilizing Walter Benjamin’s critique issued in his 1921 fragment “Capitalism as Religion,” I outline Ende’s dystopian vision of the uncontested, unquestioned reign of capitalism as a religious cult. Read together, the novel and the short story offer a way of contrasting two extreme byproducts of capitalism’s colonization of time, namely what I would call an “ideology of work” and an “ideology of growth.” The first of these is a result of capitalism’s commodification of time according to liberal ideals such as choice, freedom, and self-interest. The second is a decidedly neoliberal phenomenon in that the “financialization of everything,” to use David Harvey’s phrase, results in the ever-present expectation of unlimited, exponential growth. By drawing out these two interconnected ideologies through close readings, the subtle processes of capitalism’s colonization of time are revealed.

Regression and new beginnings: Michael, Alice and Enid Balint and the circulation of ideas.

Science.gov (United States)

Sklar, Jonathan

2012-08-01

This article offers a new evaluation of Michael Balint's history. It starts with his growing up in Hungary and examines the central concepts of his writing: the analytic pair, regression and the basic fault and creativity, up to and including his renowned work on the eponymous Balint groups (which forged a unique link between psychoanalysis and medicine). While his name is, of course, well known, this article aims to bring his ideas to the attention of a modern analytic audience. Having trained in the 1920s with Ferenczi, Balint brought Ferenczi's literary inheritance to England where he lived until his death in 1970. His connections to Klein, Winnicott and Lacan, all of whom respected his analytic stance, are also examined. Furthermore, this article argues that his ideas were filtered through the theoretical lens of his first wife Alice Balint and later through Enid Balint, both of whom played a key - and rarely recognised - role in the development of his thought. It ends with a brief discussion of his ideas on analytic training and his quest, successful only after his death, to publish the complete Freud-Ferenczi correspondence, together with Ferenczi's diary. Copyright © 2012 Institute of Psychoanalysis.

Rezension von: Brigitte Aulenbacher, Michael Meuser, Birgit Riegraf: Soziologische Geschlechterforschung. Eine Einführung. Wiesbaden: VS Verlag für Sozialwissenschaften 2010.

Directory of Open Access Journals (Sweden)

Heike Kahlert

2011-01-01

Full Text Available Das Lehrbuch von Brigitte Aulenbacher, Birgit Riegraf und Michael Meuser zielt darauf, wichtige Entwicklungen und Etappen der soziologischen Geschlechterforschung zu rekonstruieren, Forschungsfelder zu beschreiben, Anschlüsse an angrenzende Bereiche aufzuzeigen und zukünftige Fragen zu skizzieren. Dieser hoch gesteckte Anspruch gelingt weitgehend, wobei notwendig Akzente gesetzt und zwangsläufig Leerstellen in Kauf genommen werden. Offen bleibt in der intendierten zeit- und wissenschaftsgeschichtlichen Orientierung der Darstellung aber leider, was genau das Soziologische an der Geschlechterforschung ist und wie sich die Geschlechterforschung in Bezug auf ihre Wurzeln in der Soziologie positionieren könnte und sollte.

Alternatives for Jet Engine Control. Volume 1: Modelling and Control Design with Jet Engine Data

Science.gov (United States)

Sain, M. K.

1985-01-01

This document compiles a comprehensive list of publications supported by, or related to, National Aeronautics and Space Administration Grant NSG-3048, entitled "Alternatives for Jet Engine Control". Dr. Kurt Seldner was the original Technical Officer for the grant, at Lewis Research Center. Dr. Bruce Lehtinen was the final Technical Officer. At the University of Notre Dame, Drs. Michael K. Sain and R. Jeffrey Leake were the original Project Directors, with Dr. Sain becoming the final Project Director. Publications cover work over a ten-year period. The Final Report is divided into two parts. Volume i, "Modelling and Control Design with Jet Engine Data", follows in this report. Volume 2, "Modelling and Control Design with Tensors", has been bound separately.

La Habana escultórica: de La Giraldilla a Lennon

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Pereira, María de los Ángeles

2009-12-01

Full Text Available Public sculpture accompanied Havana’s architectural and urban development from its origin through its consolidation as a modern city towards the late 19th and first decades of the 20th Centuries. This substantially contributed to form the city’s profiles and to grant Havana those massive dimensions that characterize it as the Cuban capital. The development of commemorative monuments reflects both the repertoire of icons of the Cuban nation throughout its historical process, and the evolution of the aesthetic course towards a ormal and conceptual renewal that eventually granted this artistic expression a leading role within the Cuban culture.La escultura pública acompañó al desarrollo arquitectónico y urbanístico de La Habana desde su surgimiento hasta su cabal consolidación como ciudad moderna hacia finales del siglo XIX y primeras décadas del XX, contribuyendo de modo sustancial a la configuración de sus perfiles y a la monumentalidad que la caracteriza como capital de Cuba. El desarrollo del arte monumentario conmemorativo, además de reflejar el repertorio icónico de la nación cubana a lo largo de su proceso histórico, constituye un reflejo de la evolución de los derroteros estéticos en el tránsito hacia una renovación formal y conceptual que, finalmente, coloca a esta manifestación en un lugar protagonista entre de las diferentes expresiones de su cultura artística cubana.

A representação discursiva do ator social Michael Jackson e de sua morte em gêneros da esfera jornalística

Directory of Open Access Journals (Sweden)

Maria Aparecida Resende Ottoni

2014-05-01

Full Text Available Neste artigo, investigamos como se dá a representação discursiva de um mesmo fato e do principal ator social nele envolvido, em diferentes gêneros distintos, a saber: reportagem; notícia; editorial; artigo de opinião; e carta do leitor. Nosso intuito é perquirir se há diferenças nas escolhas para representação de um mesmo fato e no modo como o ator social principal é representado nesses gêneros,bem como quais as razões e efeitos dessas diferenças. Nesse sentido, selecionamos textos que tratam da morte de Michael Jackson, os quais são analisados com base nos pressupostos da Análise de Discurso Crítica e na proposta de van Leeuwen (1997 para o estudo da representação de atores sociais. A análise revelou que, em todos os gêneros, a representação de modo ativo, pessoal e por classificação específica é dominante e que, nos gêneros que representam os núcleos jornalista e empresa predomina a nomeação e, nos que retratam os núcleos colaborador e leitor, a classificação. Prevalece, ainda, a classificação por valoração, o que colabora, sobremaneira, para a produção de uma mescla na representação do ator social Michael Jackson. Essa mescla também é marcada por meio da intertextualidade manifesta.

Michael Polanyi's Philosophy of Science

Indian Academy of Sciences (India)

Positivism may be said to be the outcome of the changing contours of modern science that relies solely on observation, experimentation, and measurement. Experiments in modern science are designed solely to elicit 'yes' or 'no' for an answer. The resultant facts can be fitted into clusters, groups, manifolds, and sets.

LOS DESAFÍOS DEL DISCURSO DE LA ESTRATEGIA EN LAS ORGANIZACIONES: UNA MIRADA SOBRE LA POSICIÓN DE LA ESTRATEGIA COMPETITIVA DE MICHAEL PORTER

OpenAIRE

Neyda Ibáñez; Ruben Castillo; Alfredo Núñez

2010-01-01

El propósito se centró en interpretar los desafíos del discurso de la estrategia en las organizaciones, tomando como principal exponente a la Estrategia competitiva de Michael Porter. Para ello, se abordó desde el paradigma interpretativo, con un enfoque cualitativo, usando el método hermenéutico en un contexto teórico enunciativo, documental. Se concluye que los desafíos del discurso de la estrategia en las organizaciones, dependerán de la creatividad, productividad y la capacidad de poder c...

Diffusible gradients are out - an interview with Lewis Wolpert. Interviewed by Richardson, Michael K.

Science.gov (United States)

Wolpert, Lewis

2009-01-01

In 1969, Lewis Wolpert published a paper outlining his new concepts of "pattern formation" and "positional information". He had already published research on the mechanics of cell membranes in amoebae, and a series of classic studies of sea urchin gastrulation with Trygve Gustavson. Wolpert had presented his 1969 paper a year earlier at a Woods Hole conference, where it received a very hostile reception: "I wasnt asked back to America for many years!". But with Francis Crick lining up in support of diffusible morphogen gradients, positional information eventually became established as a guiding principle for research into biological pattern formation. It is now clear that pattern formation is much more complex than could possibly have been imagined in 1969. But Wolpert still believes in positional information, and regards intercalation during regeneration as its best supporting evidence. However, he and others doubt that diffusible morphogen gradients are a plausible mechanism: "Diffusible gradients are too messy", he says. Since his retirement, Lewis Wolpert has remained active as a theoretical biologist and continues to publish in leading journals. He has also campaigned for a greater public understanding of the stigma of depression. He was interviewed at home in London on July 26th, 2007 by Michael Richardson.

One-pot cascade michael.cyclization reactions of ο-hydroxycinnamaldehydes: Synthesis of functionalized 2,3-dihydrobenzofuranes

Energy Technology Data Exchange (ETDEWEB)

Gwon, Sung Hyuk; Kim, Sunggon [Kyonggi Univ., Suwon (Korea, Republic of)

2012-04-15

We described the cascade Michael.cyclization reaction of o-hydroxycinnamaldehydes with diethyl α-bromomalonate promoted by potassium carbonate. The reactions provided functionalized 2,3-dihydrobenzofurans in good yields for a variety of o-hydroxyaromatic α,β-unsaturated aldehydes. Current work focuses on expanding the scope of this reaction to other substrates such as sulfur yields, and on developing an efficient catalytic asymmetric variant. 2,3-Dihydrobenzofurans are found in numerous biologically active natural products and synthetic compounds. These are an attractive type of oxygenated compound because their basic core skeleton is present in neolignans, pterocarpans, and synthetic drugs used in the treatment of pulmonary hypertension, atherosclerotic peripheral arterial disease, and central nervous system trauma and ischemia. Owing to the importance of their structures, numerous synthetic methods for 2,3-dihydrobenzofurans have been developed, primarily: radical cyclizations, Lewis acid promoted reactions, anionic cyclizations, and transition-metal catalyzed processes. However, these methods cannot be generalized as much as is desirable, and they yielded poor chemo- and/or stereoselectivities. Hence, the development of an efficient enantioselective synthetic method for obtaining 2,3-dihydrobenzofuran scaffolds attracted our attention.

One-pot cascade michael.cyclization reactions of ο-hydroxycinnamaldehydes: Synthesis of functionalized 2,3-dihydrobenzofuranes

International Nuclear Information System (INIS)

Gwon, Sung Hyuk; Kim, Sunggon

2012-01-01

We described the cascade Michael.cyclization reaction of o-hydroxycinnamaldehydes with diethyl α-bromomalonate promoted by potassium carbonate. The reactions provided functionalized 2,3-dihydrobenzofurans in good yields for a variety of o-hydroxyaromatic α,β-unsaturated aldehydes. Current work focuses on expanding the scope of this reaction to other substrates such as sulfur yields, and on developing an efficient catalytic asymmetric variant. 2,3-Dihydrobenzofurans are found in numerous biologically active natural products and synthetic compounds. These are an attractive type of oxygenated compound because their basic core skeleton is present in neolignans, pterocarpans, and synthetic drugs used in the treatment of pulmonary hypertension, atherosclerotic peripheral arterial disease, and central nervous system trauma and ischemia. Owing to the importance of their structures, numerous synthetic methods for 2,3-dihydrobenzofurans have been developed, primarily: radical cyclizations, Lewis acid promoted reactions, anionic cyclizations, and transition-metal catalyzed processes. However, these methods cannot be generalized as much as is desirable, and they yielded poor chemo- and/or stereoselectivities. Hence, the development of an efficient enantioselective synthetic method for obtaining 2,3-dihydrobenzofuran scaffolds attracted our attention

Mother's love' for bacterial babies: the commitment of Audrey Michael, Mition Yoannes and Tilda Orami to medical research.

Science.gov (United States)

Gibbs, Tammy; Vilakiva, Geraldine

2013-01-01

Audrey Michael, Mition Yoannes and Tilda Orami are long-term health researchers at the Papua New Guinea Institute of Medical Research (PNGIMR). Face-to-face interviews were conducted with all three women for the purpose of profiling women who are leaders in health and medicine in Papua New Guinea. They were asked questions about their early life and childhood, education, work life and training, and mentors who have supported their career path and leadership role. Audrey, Mition and Tilda have all made significant contributions to the PNGIMR and to the health of the people of PNG. In particular, all three have been part of pneumococcal conjugate vaccine (PCV) studies--looking at the safety, immunogenicity and priming for immunological memory of a 7-valent PCV and investigating the safety and immune responses to two different, recently licensed types of PCV, a 13-valent and a 10-valent vaccine.

Guest Foreword from Michael Thomas CMG QC

Directory of Open Access Journals (Sweden)

Michael Thomas

2012-04-01

precedents and thought in a unique legal market in which ideas drawn from Islamic law, civil law and common law can intermingle and blend. It is not surprising therefore to see that this new publication will be dedicated to the subject of international law, both public and private. Its laudable aim is to promote legal discourse around the world, and to promote a wider international understanding of contemporary legal issues for the common benefit. As an open access, bilingual journal, addressing topics concerning any jurisdiction, I hope it will reach a wide audience, and fulfil its aim of promoting understanding between different cultures. I am sure that the journal will not only benefit Qatar’s legal community by advancing academic and practice-based legal discussion. I am also confident that it will stimulate thought in the global legal community at large. May I wish it every success and a long life. Michael Thomas CMG QC

Some considerations about the theory of intelligent design

Directory of Open Access Journals (Sweden)

JUAN E CARREÑO

2009-01-01

Full Text Available The so-called theory of intelligent design (ID has gained a growing reputation in the Anglo-Saxon culture, becoming a subject of public debate. The approaches that constitute the core of this proposal, however, have been poorly characterized and systematized. The three most significant authors of ID are certainly Michael Behe, William Dembski and Stephen Meyer. Beyond the differences that can be distinguished in the work of each of them, the central fact in their arguments is the complexity of living organisms, which according to these authors, escapes any kind of natural explanation. In effect, according to the authors of ID, the irreducible complexity that can be detected in the natural world would allow to infer design in a scientifically valid way, even though many of them prefer to remain silent regarding the identity and attributes of the designer. We think that under this proposal, remains a deep epistemological confusion, since its very structure combines methodologies that are beyond the scope of historical and natural evolutionary theories. We also reject the claim that ID is a legitimate scientific theory, because it does not exhibit the classical characteristics that a scientific kind of knowledge must have.

LOS DESAFÍOS DEL DISCURSO DE LA ESTRATEGIA EN LAS ORGANIZACIONES: UNA MIRADA SOBRE LA POSICIÓN DE LA ESTRATEGIA COMPETITIVA DE MICHAEL PORTER

Directory of Open Access Journals (Sweden)

Neyda Ibáñez

2010-04-01

Full Text Available El propósito se centró en interpretar los desafíos del discurso de la estrategia en las organizaciones, tomando como principal exponente a la Estrategia competitiva de Michael Porter. Para ello, se abordó desde el paradigma interpretativo, con un enfoque cualitativo, usando el método hermenéutico en un contexto teórico enunciativo, documental. Se concluye que los desafíos del discurso de la estrategia en las organizaciones, dependerán de la creatividad, productividad y la capacidad de poder crear conocimiento, ideas y manejar la información.

Building the "fable hospital"--the CEO's perspective: an interview with Michael H. Covert, president and chief executive officer, Palomar Pomerado Health. Interview by David A Tam.

Science.gov (United States)

Covert, Michael

2012-01-01

Hospital construction is a significant event in any health system. The financial implications are great, especially at a time of shrinking capital resources. Personnel are affected, as are the processes to perform their tasks. Often, new facilities are catalysts that change organizational culture; it has been clearly shown that new facilities have a positive impact on patient satisfaction scores. The members of the C-suite of a hospital/health system play important roles in construction projects. However, no one is more critical to the success of such major endeavors than the chief executive officer (CEO). The CEO sets the tone for the project, giving direction to the design and construction process that may have implications for the rest of the organization. Palomar Pomerado Health (PPH) is the largest public health district in California. In 2002, the PPH governing board authorized the creation of a new facility master plan for the district, which included the construction of a replacement facility for its tertiary care trauma center. The new Palomar Medical Center is slated to open in August 2012. HERD had the opportunity to speak with PPH CEO Michael H. Covert on the role of the CEO in the building of this "fable hospital".

Michael Haneke. Nostalgia de redención en su “trilogía de la glaciación”

Directory of Open Access Journals (Sweden)

Juan Orellana Gutiérrez de Terán

2015-05-01

Full Text Available Michael Haneke es considerado como uno de los cineastas europeos más críticos con el desenlace de la sociedad capitalista. En sus tres primeras películas, conocidas como La trilogía de la glaciación, sienta las bases ideológicas de su posterior trayectoria. Detrás de su lectura crítica es posible descubrir una nostalgia de liberación, de redención antropológica y social de fondo. En este artículo se analizan las metáforas del lenguaje fílmico de las tres obras, entendiendo la trilogía como un marco semántico y epistemológico integrado y coherente. En este artículo se concluye que en ellas no sólo se constata el desorden moral y antropológico de la sociedad posmoderna, sino que se apuntan el deseo y la necesidad de una salida en clave reparadora.

Commonalities and Differences Between Max Weber and Michael Foucault on the Theme of “Rationalization of the Body”(“Bedenin Ussallaşması” Teması Üzerinde Max Weber ve Michael Foucault Arasındaki Yakınsamalar ve Farklılıklar

Directory of Open Access Journals (Sweden)

Buğra ÖZER

2010-01-01

Full Text Available The main objective of this paper is to elucidate the very nature of ‘the rationalization of the body’ in regard to the convergence and divergences as envisioned in the works of Max Weber and Michael Foucault. While both of the thinkers may be deemed to be important critiques of the modernity process, their insights reveal certain commonalities as the came to deal with the rationalization of the body and individuation of the body along with differences that can be traced back to their roots in their critiques about the modernity project. In such respect, the study emphasizes that rationalization of the body has been a complex process and it italicizes that different dynamics came to redefine the body and individuate the individual along with the continuation of the process.

Greener manufacturing and operations: from design to delivery and back

National Research Council Canada - National Science Library

Sarkis, Joseph

2001-01-01

... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Implementing the industrial ecology approach with reverse logistics Michael Martin, University of Exeter, UK 1.1 Levels at which the concept can be applied...

Intelligent Design versus Evolution

Directory of Open Access Journals (Sweden)

Nathan Aviezer

2010-07-01

Full Text Available Intelligent Design (ID burst onto the scene in 1996, with the publication of Darwin’s Black Box by Michael Behe. Since then, there has been a plethora of articles written about ID, both pro and con. However, most of the articles critical of ID deal with peripheral issues, such as whether ID is just another form of creationism or whether ID qualifies as science or whether ID should be taught in public schools. It is our view that the central issue is whether the basic claim of ID is correct. Our goal is fourfold: (I to show that most of the proposed refutations of ID are unconvincing and/or incorrect, (II to describe the single fundamental error of ID, (III to discuss the historic tradition surrounding the ID controversy, showing that ID is an example of a “god-of-the-gaps” argument, and (IV to place the ID controversy in the larger context of proposed proofs for the existence of God, with the emphasis on Jewish tradition.

ANÁLISIS DEL POTENCIAL COMPETITIVO DEL BIOETANOL EN COLOMBIA: UN ENFOQUE DESDE LAS 5 FUERZAS COMPETITIVAS DE MICHAEL PORTER

Directory of Open Access Journals (Sweden)

RAMIREZ VELASQUEZ ALEJANDRO

2012-11-01

Full Text Available La búsqueda de alternativas de producción y consumo energético requiere una mirada hacia la industria de los combustibles biológicos como el bioetanol que, como alternativa energética, permita superar los inconvenientes generados por los métodos tradicionales de producción y consumo, en especial en los temas políticos, ambientales y sociales y generar ventajas competitivas frente a otras fuentes primarias de energía. En el presente documento,a partir del modelo de las cinco (5 Fuerzas de Michael Porter, se realiza una evaluación de la industria del bioetanol como combustible alternativo y se expone qué tan atractiva o competitiva puede llegar a ser su industria en la actualidad. Para lograr este propósito, se propone una evaluación de las fuerzas competitivas a un panel de expertos, usando escalas deLikert, para encontrar el potencial de la propuesta.

Solid State Ionics: from Michael Faraday to green energy-the European dimension.

Science.gov (United States)

Funke, Klaus

2013-08-01

Solid State Ionics has its roots essentially in Europe. First foundations were laid by Michael Faraday who discovered the solid electrolytes Ag 2 S and PbF 2 and coined terms such as cation and anion , electrode and electrolyte . In the 19th and early 20th centuries, the main lines of development toward Solid State Ionics, pursued in Europe, concerned the linear laws of transport, structural analysis, disorder and entropy and the electrochemical storage and conversion of energy. Fundamental contributions were then made by Walther Nernst, who derived the Nernst equation and detected ionic conduction in heterovalently doped zirconia, which he utilized in his Nernst lamp. Another big step forward was the discovery of the extraordinary properties of alpha silver iodide in 1914. In the late 1920s and early 1930s, the concept of point defects was established by Yakov Il'ich Frenkel, Walter Schottky and Carl Wagner, including the development of point-defect thermodynamics by Schottky and Wagner. In terms of point defects, ionic (and electronic) transport in ionic crystals became easy to visualize. In an 'evolving scheme of materials science', point disorder precedes structural disorder, as displayed by the AgI-type solid electrolytes (and other ionic crystals), by ion-conducting glasses, polymer electrolytes and nano-composites. During the last few decades, much progress has been made in finding and investigating novel solid electrolytes and in using them for the preservation of our environment, in particular in advanced solid state battery systems, fuel cells and sensors. Since 1972, international conferences have been held in the field of Solid State Ionics, and the International Society for Solid State Ionics was founded at one of them, held at Garmisch-Partenkirchen, Germany, in 1987.

Solid State Ionics: from Michael Faraday to green energy—the European dimension

Science.gov (United States)

Funke, Klaus

2013-01-01

Solid State Ionics has its roots essentially in Europe. First foundations were laid by Michael Faraday who discovered the solid electrolytes Ag2S and PbF2 and coined terms such as cation and anion, electrode and electrolyte. In the 19th and early 20th centuries, the main lines of development toward Solid State Ionics, pursued in Europe, concerned the linear laws of transport, structural analysis, disorder and entropy and the electrochemical storage and conversion of energy. Fundamental contributions were then made by Walther Nernst, who derived the Nernst equation and detected ionic conduction in heterovalently doped zirconia, which he utilized in his Nernst lamp. Another big step forward was the discovery of the extraordinary properties of alpha silver iodide in 1914. In the late 1920s and early 1930s, the concept of point defects was established by Yakov Il'ich Frenkel, Walter Schottky and Carl Wagner, including the development of point-defect thermodynamics by Schottky and Wagner. In terms of point defects, ionic (and electronic) transport in ionic crystals became easy to visualize. In an ‘evolving scheme of materials science’, point disorder precedes structural disorder, as displayed by the AgI-type solid electrolytes (and other ionic crystals), by ion-conducting glasses, polymer electrolytes and nano-composites. During the last few decades, much progress has been made in finding and investigating novel solid electrolytes and in using them for the preservation of our environment, in particular in advanced solid state battery systems, fuel cells and sensors. Since 1972, international conferences have been held in the field of Solid State Ionics, and the International Society for Solid State Ionics was founded at one of them, held at Garmisch-Partenkirchen, Germany, in 1987. PMID:27877585

Solid State Ionics: from Michael Faraday to green energy—the European dimension

Directory of Open Access Journals (Sweden)

Klaus Funke

2013-01-01

Full Text Available Solid State Ionics has its roots essentially in Europe. First foundations were laid by Michael Faraday who discovered the solid electrolytes Ag2S and PbF2 and coined terms such as cation and anion, electrode and electrolyte. In the 19th and early 20th centuries, the main lines of development toward Solid State Ionics, pursued in Europe, concerned the linear laws of transport, structural analysis, disorder and entropy and the electrochemical storage and conversion of energy. Fundamental contributions were then made by Walther Nernst, who derived the Nernst equation and detected ionic conduction in heterovalently doped zirconia, which he utilized in his Nernst lamp. Another big step forward was the discovery of the extraordinary properties of alpha silver iodide in 1914. In the late 1920s and early 1930s, the concept of point defects was established by Yakov Il'ich Frenkel, Walter Schottky and Carl Wagner, including the development of point-defect thermodynamics by Schottky and Wagner. In terms of point defects, ionic (and electronic transport in ionic crystals became easy to visualize. In an 'evolving scheme of materials science', point disorder precedes structural disorder, as displayed by the AgI-type solid electrolytes (and other ionic crystals, by ion-conducting glasses, polymer electrolytes and nano-composites. During the last few decades, much progress has been made in finding and investigating novel solid electrolytes and in using them for the preservation of our environment, in particular in advanced solid state battery systems, fuel cells and sensors. Since 1972, international conferences have been held in the field of Solid State Ionics, and the International Society for Solid State Ionics was founded at one of them, held at Garmisch-Partenkirchen, Germany, in 1987.

JPRS Report, Arms Control

Science.gov (United States)

1989-05-09

drop his ANZUS bombshell by his visit to Strawberry Fields in New York with Yoko Ono, the widow of Beatle John Lennon. The Opposition regarded Mr...Murphy; THE NEW ZEALAND HERALD 27 Apr] 11 Lange Said To Risk Leadership [S. Collins; NEW ZEALAND HERALD 27 Apr] 12 Bush Administration Called...30-31 [Article by Hsiao Li: "Outlook for Talks on Conven- tional Forces in Europe"] [Text]Special dispatch from Vienna The talks on Conven- tional

Dark cities? Developing a methodology for researching dark tourism in European cities

OpenAIRE

Kennell, James; Powell, Raymond

2016-01-01

Despite the recent growth of research into dark tourism (Dale & Robinson, 2011; Lennon & Foley, 2000; Stone, 2013; Tarlow, 2005) and the growth of the dark tourism market (Biran & Hyde, 2013; Stone 2005; Stone & Sharpley, 2008), there has been little interest shown in understanding the relationship between dark tourism and urban tourism (Page & Hall 2002). This paper presents the initial findings of a research project that investigates the dark tourism products offered by European cities. A s...

Sound / Märt Milter

Index Scriptorium Estoniae

Milter, Märt

1998-01-01

Uutest plaatidest Gary Moore "Out In The Fields", Pete Rock "Soul Survivor", Brand Nubian "Foundation", OST "Fear And Loathing In Las Vegas", "FFRR Classics 1988-1998",OST "Saving Private Ryan", John Lennon "Anthology", "Red, Hot + Rhapsody", Karl Jenkins/Adiemus III "Dances Of Time", Five Fifteen "Six Dimensions Of The Electric Camembert", Bruce Hornsby "Spirit Trail", Dune & London Session Orchestra "Forever And Ever", Redman "Docs Da Name 2000", Jennifer Rush "Classics", Ice Cube "War & Peace vol.1"

Tanatoturystyka - kontrowersyjne oblicze turystyki kulturowej

OpenAIRE

Tanaś, Sławoj

2006-01-01

Apart from its leisure, cognitive and specialist functions, tourism also has an educational function. It is in the context of cognition and education that one should perceive journeys to the places of disasters, tragedies and death, defined in 1996 as dark tourism [Foley, Lennon 1996] or "thanatourism" [Seaton 1996]. What motivates the need for visiting these types of places? Undoubtedly, the shaping of such needs is encouraged by the media that create reality nowadays, and easy access to inf...

ETAC reagents: A new class of sulfhydryl site-specific radiolabelling probes for antibodies

International Nuclear Information System (INIS)

del Rosario, R.B.; Brocchini, S.J.; Baron, L.A.; Smith, R.H.; Lawton, R.G.; Wahl, R.L.

1990-01-01

A new class of bis-alkylating Michael reagents, equilibrium transfer crosslink reagents, 'ETAC', which combine the techniques of crosslinking with tethering have been synthesized. Following a succession of Michael and retro-Michael additions and elimination of the arylsulfone groups, reduced heavy-heavy and heavy-light disulfide links of an anti-ovarian IgG2a monoclonal antibody, 5G6.4, were site-specifically re-annealed via a 3-carbon bridge having a tether branch containing a designated label

Participants in the “Schweizer Jugendforscht’” projects at CERN under the supervision of Günther Dissertori, professor at the Swiss Federal Institute of Technology (ETH Zürich) and other members of ETH Zürich, Werner Lustermann and Michael Dittmar.

CERN Multimedia

2005-01-01

Participants in the “Schweizer Jugendforscht’” projects at CERN under the supervision of Günther Dissertori, professor at the Swiss Federal Institute of Technology (ETH Zürich) and other members of ETH Zürich, Werner Lustermann and Michael Dittmar.

Analysis of Media Stereotypes of the Russian Image in Media Studies in the Student Audience (example: the screen versions of Jules Verne's Novel “Michael Strogoff”

Directory of Open Access Journals (Sweden)

Alexander Fedorov

2014-09-01

Full Text Available As a result of the analysis students come to the conclusion that the screen adaptations of Jules Verne's novel ''Michael Strogoff'' create, though an oversimplified and adapted to western stereotypes of perception, but a positive image of Russia – as a stronghold of European values at the Asian frontiers, a country with a severe climate, boundless Siberian spacious areas, manly and patriotic warriors, a wise monarchy. At the same time, both Jules Verne's novel and its screen adaptations contain clear-cut western pragmatism – the confidence that if a man has a proper will he can rule his destiny.

Latter-day Mother Irelands: The Role of Women in Michael Collins and The Wind that Shakes the Barley

Directory of Open Access Journals (Sweden)

Pilar Villar-Argáiz

2007-03-01

Full Text Available Despite the experimental and subversive work of Irish feminist filmmakers such as Pat Murphy and Margo Harkin in the 1980s, as Gerardine Meaney has contended, “the image of woman as Ireland, Ireland as woman, remains powerful and pervasive in the new Irish cinema” (1998: 250. The cinematic convention of representing Ireland through female characters becomes particularly relevant in two recent Irish historical films: Michael Collins (1996, directed and written by Irish Neil Jordan, and The Wind that Shakes the Barley (2006, written by Scottish Paul Laverty and directed by English Ken Loach. In their dealing with themes such as military occupation, colonisation and the heated debate about the Treaty, both films maintain the nationalist rhetoric that represents Ireland as a woman/mother in a direct manner. Over the course of this essay, I shall try to chart the implications of both films’ representations of women, with a view to demonstrating how, even at present, the trope of Mother Ireland continues to be deep in the national unconscious.

Jan Rak and Michael J. Tannenbaum present the book "High-pT physics in the heavy ion era"

CERN Multimedia

2013-01-01

Thursday 13 June 2013 from 4 p.m. to 5 p.m. in the Library, Bldg. 52 1-052 The book provides an overview of the basic concepts of large transverse momentum particle physics, with a focus on pQCD phenomena. It examines high-pT probes of relativistic heavy-ion collisions and will serve as a handbook for those working on RHIC and LHC data analyses. Starting with an introduction and review of the field, the authors look at basic observables and experimental techniques, concentrating on relativistic particle kinematics, before moving onto a discussion about the origins of high-pT physics. The main features of high-pT physics are placed within a historical context and the authors adopt an experimental outlook, highlighting the most important discoveries leading up to the foundation of modern QCD theory. High-pT physics in the heavy ion era, by Jan Rak and Michael J. Tannenbaum,  Cambridge University Press, 2013, ISBN  9780521190299. *Coffee will be served from 3 p.m.*

Sustainable shape memory polymers based on epoxidized natural rubber cured by zinc ferulate via oxa-Michael reaction

Directory of Open Access Journals (Sweden)

Xuhui Zhang

2015-10-01

Full Text Available Although various shape memory polymers (SMPs or diverse applications have been widely reported, the SMPs based on rubbers have been rarely realized due to the low triggering temperature of rubbers. In another aspect, the SMPs based on sustainable substances are highly desired for the growing shortage in fossil resources. In the present study, we accordingly developed the sustainable SMPs with tunable triggering temperature, based on natural rubber (NR and ferulic acid (FA as the raw materials. Specifically, the SMPs are based on a crosslinked network of epoxidized natural rubber (ENR crosslinked by in situ formed zinc ferulate (ZDF via oxa-Michael reaction. The excellent shape memory effect (SME is found in these SMPs, as evidenced by the high fixity/recovery ratio and the tunable triggering temperature. With the incorporation of natural halloysite nanotubes (HNTs, the stress and recovery rate of the SMPs are found to be tunable, which widens the application of this kind of SMPs. The combination of adoption of sustainable raw materials, and the excellent and tunable SME makes these SMPs potentially useful in many applications, such as various actuators and heat-shrinkable package materials.

A designated centre for people with disabilities operated by St Michael's House, Dublin 17

LENUS (Irish Health Repository)

O'Shea, Eamon

2011-02-14

Abstract Background Current projections indicate that there will be a significant increase in the number of people with dementia in Ireland, from approximately 40,000 at present to 100,000 by 2036. Psychosocial interventions, such as reminiscence, have the potential to improve the quality of life of people with dementia. However, while reminiscence is used widely in dementia care, its impact on the quality of life of people with dementia remains largely undocumented and there is a need for a robust and fair assessment of its overall effectiveness. The DementiA education programme incorporating REminiscence for Staff study will evaluate the effectiveness of a structured reminiscence-based education programme for care staff on the quality of life of residents with dementia in long-stay units. Methods\\/Design The study is a two-group, single-blind cluster randomised trial conducted in public and private long-stay residential settings in Ireland. Randomisation to control and intervention is at the level of the long-stay residential unit. Sample size calculations suggest that 18 residential units each containing 17 people with dementia are required for randomisation to control and intervention groups to achieve power of at least 80% with alpha levels of 0.05. Each resident in the intervention group is linked with a nurse and care assistant who have taken the structured reminiscence-based education programme. Participants in the control group will receive usual care. The primary outcome is quality of life of residents as measured by the Quality of Life-AD instrument. Secondary outcomes include agitation, depression and carer burden. Blinded outcome assessment is undertaken at baseline and at 18-22 weeks post-randomisation. Discussion Trials on reminiscence-based interventions for people with dementia have been scarce and the quality of the information arising from those that have been done has been undermined by methodological problems, particularly in relation to scale

Panel discussion on rock mechanics issues in repository design

International Nuclear Information System (INIS)

Bieniawski, Z.T.; Kim, K.S.; Nataraja, M.

1996-01-01

The panel discussion was introduced by Mr. Z.T.(Richard) Bieniawski and then continued with five additional speakers. The topics covered in the discussion included rock mechanics pertaining to the design of underground facilities for the disposal of radioactive wastes and the safety of such facilities. The speakers included: Mr. Kun-Soo Kim who is a specialist in the area of rock mechanics testing during the Basalt Waste Isolation Project; Dr. Mysore Nataraja who is the senior project manager with the NRC; Dr. Michael Voegele who is the project manager for Science Applications International Corporation (SAIC) on the Yucca Mountain Project; Dr. Edward Cording who is a member of the Nuclear Waste Technical Review Board; and Dr. Hemendra Kalia who is employed by Los Alamos National Laboratory and coordinates various activities of testing programs at the Yucca Mountain Site

Examination and comparative study of the Ascension of The Prophet of Islam In The View Of Michael Sells And Anne-mari e Shamil with Inter- Religious Attitude

Directory of Open Access Journals (Sweden)

Mahdi Azadi

2015-09-01

Full Text Available Michael Sells, American scholar of Quran,about the Ascension (Mi,raj of the prophet (PBUH focuses on three issues: First, the Mi,raj term is not used in the Quran and the ascension of the explanation is not enough. second, Mohammad is no different from the miracle of the Quran is the miracle of God,he is not anything else, Quran states. Third, Ascension of the prophet (PBUH has been in sleep and dream.According to him, the discussion about the layers of the subject is based mainly on the evidence of Quran.In this case, only limited information can be found in the Asra chapter (sooreh of the Quran.In addition, he has tried to make the Ascension event from Jewish traditions and the effects Bvdaysm.actually the orientalist`s goal is to prove the absence of ascension of the prophet(PBUH.  In contrast, Anne-marie Shamil stayes that prophet`s ascension derived from the first verse of Asra sura and believes that two processes(horizontal and verticalfor prophet happened.and unlike Michael,he knows mi,raj from the God miracles.Anne-Marie because her sufficient the Sunni sources is doubt with belief in the physical and spiritual ascension,in some of her votes,such as; visible or not visible in the ascension of God by the prophet.Despite the fundamental criticism that some elements of the theory of two Orientalists arrived,positive points are observed in their ideas.in this article we have tried to express the views of the Orientalists, then to review their ideas considered

Suspense, culpa y cintas de vídeo. Caché/Escondido de Michael Haneke

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Miguel Martínez-Cabeza

2011-12-01

Full Text Available Caché/Escondido (2005 representa dentro de la filmografía de Michael Haneke el ejemplo más destacado de síntesis de los planteamientos formales e ideológicos del cineasta austriaco. Este artículo analiza el filme como manifiesto cinematográfico y como explotación de las convenciones genéricas para construir un modelo de espectador reflexivo. La investigación del modo en que el director plantea y abandona las técnicas del suspense aporta claves para explicar el éxito casi unánime de crítica y la respuesta mucho menos homogénea de las audiencias. El desencadenante de la trama, unas cintas de vídeo que reciben los Laurent, es alusión directa a Carretera Perdida (1997 de David Lynch; no obstante, el misterio acerca del autor de la videovigilancia pierde interés en relación al sentimiento de culpa que desencadena en el protagonista. El episodio infantil de celos y venganza hacia un niño argelino y la actitud del Georges adulto representan una alegoría de la relación de Francia con su pasado colonial que tampoco cierra la narración de Haneke. Es precisamente la apertura formal con que el filme (desestructura cuestiones actuales como el límite entre la responsabilidad individual y colectiva lo que conforma un espectador tan distanciado de la diégesis como consciente de su propio papel de observador.

Quality evaluation of commercially sold table water samples in Michael Okpara University of Agriculture, Umudike, Nigeria and surrounding environments

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D.O. Okorie

2015-01-01

Full Text Available In Michael Okpara University of Agriculture, Umudike, Nigeria (MOUAU and surrounding environments, table water of different brands is commercially hawked by vendors. To the best of our knowledge, there is no scientific documentation on the quality of these water samples. Hence this study which evaluated the quality of different brands of water samples commercially sold in MOUAU and surrounding environments. The physicochemical properties (pH, total dissolved solids (TDS, biochemical oxygen demand (BOD, total hardness, dissolved oxygen, Cl, NO3, ammonium nitrogen (NH3N, turbidity, total suspended solids (TSS, Ca, Mg, Na and K of the water samples as indices of their quality were carried out using standard techniques. Results obtained from this study indicated that most of the chemical constituents of these table water samples commercially sold in Umudike environment conformed to the standards given by the Nigerian Industrial Standard (NIS, World Health Organization (WHO and American Public Health Association (APHA, respectively, while values obtained for ammonium nitrogen in these water samples calls for serious checks on methods of their production and delivery to the end users.

Entrevista com Michael R. KatzDOI: 10.5007/2175-7968.2011v1n27p329

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Maria Lúcia Barbosa de Vasconcellos

2011-11-01

Full Text Available Michael R. Katz graduated from Horace Mann School (New York and attended Williams College (Massachusetts, where he was the very first Russian major. Following graduation in 1966, he studied at Oxford University and the University of Leningrad, where he received his D.Phil. (or Ph.D. in Literature from Oxford. He first taught Russian at Williams and in 1984 became Chair of the Department of Slavic Language and Director of the Title VI Center for Russian and East European Studies at the University of Texas at Austin,. In 1998, he accepted a position as Dean of Language Schools and Schools Abroad at Middlebury College (Vermont. Since his term as Dean ended in 2004, he has been a full-time professor at the Russian Department. Prof. Katz has published several articles on literary translation and written two books. Additionally, he is a published translator of more than a dozen works into English, including novels by Herzen, Chernyshevsky, Dostoevsky, Turgenev, Tolstoy. In this interview, Katz explains how he became a translator, and addresses some important issues concerning the market for translation, his relationship with editors and publishing houses, translation and its critics, and some of the challenges he encountered translating from Russian into English.

Dual-stream accounts bridge the gap between monkey audition and human language processing. Comment on "Towards a Computational Comparative Neuroprimatology: Framing the language-ready brain" by Michael Arbib

Science.gov (United States)

Garrod, Simon; Pickering, Martin J.

2016-03-01

Over the last few years there has been a resurgence of interest in dual-stream dorsal-ventral accounts of language processing [4]. This has led to recent attempts to bridge the gap between the neurobiology of primate audition and human language processing with the dorsal auditory stream assumed to underlie time-dependent (and syntactic) processing and the ventral to underlie some form of time-independent (and semantic) analysis of the auditory input [3,10]. Michael Arbib [1] considers these developments in relation to his earlier Mirror System Hypothesis about the origins of human language processing [11].

Le Falstaff de Manfredo Maggioni et Michael Balfe : façonner un opéra italien pour le public anglais Adapting The Merry Wives of Windsor for the Italian Stage: Falstaff by Manfredo Maggioni and Michael Balfe

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Céline Frigau

2011-12-01

Full Text Available Le Falstaff de Manfredo Maggioni et Michael Balfe constitue un cas à la fois exemplaire et unique de réécriture lyrique d’une œuvre de Shakespeare. Inspiré des Merry Wives of Windsor, l’opera buffa est écrit en 1838 pour le public de l’opéra italien de Londres, par un librettiste italien et un compositeur irlandais – une première dans un théâtre où l’on ne passe commande qu’auprès de maestri italiens. Des efforts de Maggioni et de Balfe résulte un véritable opéra italien qui respecte les codes structurels, les pratiques vocales et scéniques qui le rendent reconnaissable comme opera buffa sur la scène esthétique du temps. La question de la réécriture engage ici la réflexion sur les processus intimement liés de production et de réception précis, comme sur l’horizon d’attente du public londonien pour circonscrire les frontières d’une catégorie esthétique nommée « opéra italien » qui se définit aussi et peut-être avant tout loin de la péninsule, au contact de spectateurs non italophones, au fil d’échanges à l’échelle européenne.Based on Shakespeare’s Merry Wives of Windsor, Michael Balfe’s Falstaff, created in 1838 for London’s Italian opera audiences, was the work of an Italian librettist, Manfredo Maggioni, and an Irish composer, a first in a theatre where only Italian maestri were commissioned for new works. Balfe’s and Maggioni’s combined efforts resulted in a truly genuine Italian opera buffa. Not only is it sung in Italian but it also respects the structural codes, vocal and scenic practices which make it recognizable as an opera buffa on the aesthetic stage of the time, and above all on the English stage. The issue of rewriting implies here a reflection on the intimately linked processes of production and reception. Through the study of the libretto and score, its contextualization, as well as contemporary accounts, we will be concerned both with questioning the

Analysis and Design of Complex Networks

Science.gov (United States)

2014-12-02

systems. 08-NOV-10, . : , Barlas Oguz, Venkat Anantharam. Long range dependent Markov chains with applications , Information Theory and Applications ...JUL-12, . : , Michael Krishnan, Ehsan Haghani, Avideh Zakhor. Packet Length Adaptation in WLANs with Hidden Nodes and Time-Varying Channels, IEEE... WLAN networks with multi-antenna beam-forming nodes. VII. Use of busy/idle signals for discovering optimum AP association VIII

Campaign Assessment in Counterinsurgency: Reinventing the Wheel

Science.gov (United States)

2015-04-22

Pamphlet 525-5-500: Commander’s Appreciation and Campaign Design (Washington, DC: Government Printing Office, 2008), 18. 18 Robert Axelrod and Michael D...distrust within the Johnson 60 Axelrod and Cohen, Harnessing Complexity: Organizational...Metrics in COIN: Effects Based Analysis.” Military Intelligence Professional Bulletin (April-June 2010). Axelrod , Robert and Michael D. Cohen

Building Enterprise Transition Plans Through the Development of Collapsing Design Structure Matrices

Science.gov (United States)

2015-09-17

Complete Baseline Integration Plan Example ............................................128 Appendix B. Storyboard ...on the user inputs of the relationship DSM. 131 A ppendix B . Storyboard Capt Michael Kretser Advisor: Dr. Jeffrey Ogden

Innovators: Songwriters

OpenAIRE

David Galenson

2009-01-01

Irving Berlin and Cole Porter were two of the great experimental songwriters of the Golden Era. They aimed to create songs that were clear and universal. Their ability to do this improved throughout much of their careers, as their skill in using language to create simple and poignant images improved with experience, and their greatest achievements came in their 40s and 50s. During the 1960s, Bob Dylan and the team of John Lennon and Paul McCartney created a conceptual revolution in popular mu...

Hvordan gør vi tingene her? – et Michael Eraut-inspireret fokus på sygeplejestuderendes første kliniske undervisningsforløb

DEFF Research Database (Denmark)

Jensen, Carsten Juul

2014-01-01

socializing into the hierarchy of the clinic, toward the progression from being a novice to becoming an advanced beginner, overcoming overwhelming experiences. A socialization supported by newly educated nurses who can still express their practice, or supported by their private relations. When the new nursing......This paper is part of a longitudinal development project. We try to comprehend the learning experience of nursing students during their first clinical study course, aiming to identify how and what nursing students learn to qualify the support of clinical supervisors and educators. The methology...... of the project is qualitative, inspired by the thoughts of Michael Eraut on workplace learning. Seen from the workplace perspective, learning seems to be oriented toward the situations facing the students, rather than toward fabricated study methods. The learning of nursing students seems to be oriented toward...

A stale challenge to the philosophy of science: commentary on "Is psychology based on a methodological error?" by Michael Schwarz.

Science.gov (United States)

Ruck, Nora; Slunecko, Thomas

2010-06-01

In his article "Is psychology based on a methodological error?" and based on a quite convincing empirical basis, Michael Schwarz offers a methodological critique of one of mainstream psychology's key test theoretical axioms, i.e., that of the in principle normal distribution of personality variables. It is characteristic of this paper--and at first seems to be a strength of it--that the author positions his critique within a frame of philosophy of science, particularly positioning himself in the tradition of Karl Popper's critical rationalism. When scrutinizing Schwarz's arguments, however, we find Schwarz's critique profound only as an immanent critique of test theoretical axioms. We raise doubts, however, as to Schwarz's alleged 'challenge' to the philosophy of science because the author not at all seems to be in touch with the state of the art of contemporary philosophy of science. Above all, we question the universalist undercurrent that Schwarz's 'bio-psycho-social model' of human judgment boils down to. In contrast to such position, we close our commentary with a plea for a context- and culture sensitive philosophy of science.

Enfermera: tus sentimientos también cuentan

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Castañeda Consuelo

1998-12-01

Full Text Available

We had been trained to offer help based on a protocol management mainly. However, not too many times. We have considered feelings as integrative part of our daily duties. The kind of relationship we hare at he moment nith he patient, originated a mechanic care, where principles like human warm, is not very often taken into account. Allowing us to flow our own feelings in nursering duties regardless, the emotional or even physical risk we have to take as human beings, is just part of the decision we should make in order to create a space of life inside the profession. Living potentially is a demand we have to consider seriously. As Jhon Lennon said before: "life  is something that happens, while we are always busy worried for vain things".

Estamos entrenadas para brindar cuidados basados en protocolos de manejo, donde usualmente no hay cabida para nuestros sentimientos. El tipo de relación que se establece da origen, entonces, a un cuidado mecánico, carente en ocasiones de calidez humana. Permitirnos el flujo de nuestros sentimientos en los quehaceres de enfermería, desde luego que entrañan riesgo para nuestra integridad emocional y nuestra salud en general; pero bien vale apostarle a vivir plenamente si como decía John Lennon: "La vida es algo que transcurre mientras nosotros la pasamos ocupados en otras cosas".

Evolution of generic competitive strategies and the importance of Michael E. Porter La evolución de las estrategias genéricas de competición y la influencia de Michael E. Porter A evolução das estratégias genéricas de competição e a influência de Michael E. Porter

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Wilson Weber

2010-03-01

Full Text Available Generic competitive strategies are considered almost as archetypes in Business Administration, sometimes leading to over simplification of their concepts as well as underestimation of their importance. Since publication in 1980, as part of Michael E. Porter's book Competitive Strategy, the generic strategies of Differentiation, Leadership in Total Cost and Focus have been used in whole or in part, in various approaches, accelerating dissemination of Porter's work and the subject itself. As a contribution to the development of knowledge about generic strategies, extensive research was carried out comparing the best known proposals such as such as the outpacing strategies (GILBERT; STREBEL, 1987, 1989, the value disciplines (TREACY; WIERSEMA, 1995, and the Delta Project (HAX; WILDE, 2001 among others, while adopting Porter's work (1980 as reference. It becomes evident that this work is not only versatile, as confirmed by use in proposals of other authors, but that it remains up to date, influential and can serve as a basis for conceptual advances of more recent complementary proposals and development of unique strategies by organizations.Las estrategias genéricas de competición son tratadas en Administración casi como arquetipos, lo que, a veces, puede llevar a una simplificación exagerada de sus conceptos y a la subvaloración de su relevancia. Desde su publicación en 1980, como parte del libro Compettitive Strategy, de Michael E. Porter, las estrategias genéricas de Diferenciación, Liderazgo en el Costo Total y Foco han sido utilizadas total o parcialmente en varios abordajes, acelerando la diseminación no sólo de ese trabajo de Porter, como del tema. Proponiéndose ofrecer una contribución para el desarrollo del conocimiento sobre estrategias genéricas, adoptamos el trabajo de Porter (1980 como referencia y realizamos una revisión bibliográfica profunda, comparándolo con las propuestas m

design and testing of a cupola furnace for michael okpara university

African Journals Online (AJOL)

2013-03-01

Mar 1, 2013 ... Carbon, C. %. 50.0. 57.5. 70.0. 86.0. 93.0 ... drical shape with a diameter of 380mm and a height of. 1480mm ... selection of charcoal as different from coke are as ex- amined and ..... Number of blades. 12. 2 .... cupola as modified during test running proved to be ... Ugonna Nathan Okorie, Fiepamo J. Adouyi ...

Redesigning Strategy for Irregular War: Improving Strategic Design for Planners and Policymakers to Help Defeat Groups Like the Islamic State

Science.gov (United States)

2016-12-01

Represent a Threat to the United States?,” The Hill, 03 October 2014; Brian Michael Jenkins , “What Could U.S. Boots on the Ground Do in Iraq and...Syria?,” Defense One, 15 October 2014; Brian Michael Jenkins , “Any review of Syria and Iraq strategy needs realistic reappraisal,” The Hill, 28 September...recalls his effort to help General Henri E. Navarre describe end states in the war to preserve French control of what was then Indochina:29 When

Penny Lane et Strawberry Field(s : réel, identité et fantasmagorie

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Bernard Gensane

2010-11-01

Full Text Available Les chansons « Penny Lane » et « Strawberry Fields Forever » permettent d’appréhender le thème de l’enfance chez les Beatles. De manière très différente, John Lennon et Paul McCartney s’appuient sur une visite de deux lieux réels liverpooliens pour mettre en résonance leurs visions fantasmagoriques du passé, et pour exploiter la langue (qu’ils travaillent et qui les travaille dans une perspective authentiquement artistique.

Imagine A Collective Landscape

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Manuela Silvia Campanini

2010-03-01

Full Text Available Iceland plays a key role in the circumpolar context. The research investigates the fields of both the icelandic cultural landscape perception and the icelandic cultural identity. It considers the book Ultima thule; or, a summer in Iceland and Ólafur Elíasson art works as two sides of a same medal: the Iceland on the brain concept (F. Burton. The transition from a cultural identity to a collective landscape identity is investigated analysing Imagine J. Lennon's song which inspired Yõko Ono's work art titled Imagine Peace Tower.

Operational Design of Campaigns. A Hedge against Operational Failures.

Science.gov (United States)

1990-05-07

although no firm date was given. Nixon viewed Baghdad as the "golden ring’ to be snatched. thereby successfully ending the Mesopotamia Campaign. In his mind...London: Unicorn Press. 1936. Candler, Edmund. The Long Road to Baghdad. Boston: Houghton Mifflin, 1918. Clausewitz, Carl von. On War, Trans. Michael

Speech Understanding in Air Intercept Controller Training System Design.

Science.gov (United States)

1979-01-01

Street MD 700 Utica, NY 13503chief MI Field Unit Mr. J. Michael Nyc, Pres identP.O. Box 476 Marketing Consultants Interna tional , Inc.Fort Rucker, AL... Researc h Lab Systems and Information Sciences Lab ~aman Engi neering Division Texas Instruments ~fright-Patterson AFB P. 0. Box 5936 Dayton, OH

Obituary: Michael John Seaton, 1923-2007

Science.gov (United States)

Pradhan, Anil; Nahar, Sultana

2007-12-01

Professor Michael John Seaton, hailed as the "Father of Atomic Astrophysics," passed away on May 29, 2007. He was one of the few Honorary Fellows of both the American Astronomical Society and the American Physical Society, so honored for his monumental contributions to both physics and astronomy. Mike Seaton was born on January 16, 1923 in Bristol, England. He attended Wallington County High School. But his leftist political activities, even at that stage, led to his expulsion, though he was eventually allowed to matriculate. He enlisted in the Royal Air Force as a navigator during the Second World War, and flew many dangerous missions. His legendary concentration and precision are reflected in the following anecdote. Once after a bombing mission his aircraft was lost in fog over the Alps. Seaton calculated the position and coordinates in flight to guide the aircraft. When the fog lifted, the crew found themselves flying perilously close to the mountains, but made it safely back. His associates often said, "A Seaton calculation is carried out as if his life depended on it." After the War he was admitted to University College London (UCL) as an undergraduate. Thereafter, he spent all of his professional career at UCL. Seaton received his Batchelor's degree in 1948, and his Ph.D. in 1951. His tenure at UCL coincided with the golden age of atomic astrophysics, for he was largely responsible for it. Seaton was elected Fellow of the Royal Society in 1967, and as President of the Royal Astronomical Society (RAS) in 1978. He was the recipient of an Honorary Doctorate from the Observatoire de Paris, an Honorary D.Sc. from the Queen's University of Belfast, the Gold Medal for Astronomy by the RAS, the Guthrie Medal by the Institute of Physics, the Royal Society Hughes award for lifetime work by the RAS, and several other prestigious awards. Nevertheless, as Alex Dalgarno recently remarked, Seaton was not part of the establishment because he chose not to be. Though rooted in

Phases for the value chain design and analysis in organizations

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Emilio García Vega

2015-09-01

Full Text Available Value generation is a key issue in the management of organizations because it allows the consumer satisfaction, dynamic face of competition and reward the owners or shareholders. Its treatment reflects both the academic and the business world; i.e. teachers, researchers, executives and managers of the enterprises, whether they are micro, small, medium or large. Although there are different approaches to the subject, this paper will seek to develop an approach from a competitive perspective and through the value chain, as it can be considered a valid tool for designing and analysing how organizations generate value. Also, this research tries to present the evolution of the generation of value, based on the classical models of McKinsey & Co. and Michael Porter. Then some approaches and contributions to the value chain of different authors and from different perspectives are presented, so that we can count with a number of additional ideas, which the author considers relevant to face the value chain design and analysis. Finally, on the basis of capital contribution of the mentioned Harvard University Professor, a series of recommendations for the strategic application of the value chain in the management of today's organizations, which are organized into nine phases (phases for the design and analysis of the value chain are presented.

Chairman of the DELL Board of Directors and Chief Executive Officer Michael S. Dell with CERN Director-General R. Heuer and in front of the ATLAS detector (centre) with ATLAS Deputy Spokesperson A. Lankford (left) and Information Technology Department Head F. Hemmer on 26th January 2010.

CERN Multimedia

Maximilien Brice

2010-01-01

Chairman of the DELL Board of Directors and Chief Executive Officer Michael S. Dell with CERN Director-General R. Heuer and in front of the ATLAS detector (centre) with ATLAS Deputy Spokesperson A. Lankford (left) and Information Technology Department Head F. Hemmer on 26th January 2010.

Base-catalyzed tandem Michael/dehydro-Diels-Alder reaction of α,α-dicyanoolefins with electron-deficient 1,3-conjugated enynes: a facile entry to angularly fused polycycles.

Science.gov (United States)

Zhang, Mingrui; Zhang, Junliang

2014-01-07

Angularly fused carbocyclic frameworks and their heteroatom-substituted analogues exist in many natural products that display a broad and interesting range of biological activities. Preparation of polycyclic products by cycloaddition reactions have been the long-standing hot topic in the synthetic community. Dehydro-Diels-Alder (DDA) reactions are one class of dehydropericyclic reactions that are derived conceptually by systematic removal of hydrogen atom pairs. A base-promoted tandem Michael addition and DDA reaction of α,α-dicyanoolefins with electron-deficient 1,3-conjugated enynes was realized in which a DDA reaction takes place between the arylalkynes and electron-deficient tetrasubstituted olefin. The control experiments support the stepwise anionic reaction pathway rather than the concerted reaction pathway. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Molecular Characterization of Thiols in Fossil Fuels by Michael Addition Reaction Derivatization and Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.

Science.gov (United States)

Wang, Meng; Zhao, Suoqi; Liu, Xuxia; Shi, Quan

2016-10-04

Thiols widely occur in sediments and fossil fuels. However, the molecular composition of these compounds is unclear due to the lack of appropriate analytical methods. In this work, a characterization method for thiols in fossil fuels was developed on the basis of Michael addition reaction derivatization followed by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI FT-ICR MS). Model thiol compound studies showed that thiols were selectively reacted with phenylvinylsulfone and transformed to sulfones with greater than 98% conversions. This method was applied to a coker naphtha, light and heavy gas oils, and crude oils from various geological sources. The results showed that long alkyl chain thiols are readily present in petroleum, which have up to 30 carbon atoms. Large DBE dispersity of thiols indicates that naphthenic and aromatic thiols are also present in the petroleum. This method is capable of detecting thiol compounds in the part per million range by weight. This method allows characterization of thiols in a complex hydrocarbon matrix, which is complementary to the comprehensive analysis of sulfur compounds in fossil fuels.

IUTAM Symposium on Innovative Numerical Approaches for Materials and Structures in Multi-Field and Multi-Scale Problems : in Honor of Michael Ortiz's 60th Birthday

CERN Document Server

Pandolfi, Anna

2016-01-01

This book provides readers with a detailed insight into diverse and exciting recent developments in computational solid mechanics, documenting new perspectives and horizons. The topics addressed cover a wide range of current research, from computational materials modeling, including crystal plasticity, micro-structured materials, and biomaterials, to multi-scale simulations of multi-physics phenomena. Particular emphasis is placed on pioneering discretization methods for the solution of coupled non-linear problems at different length scales. The book, written by leading experts, reflects the remarkable advances that have been made in the field over the past decade and more, largely due to the development of a sound mathematical background and efficient computational strategies. The contents build upon the 2014 IUTAM symposium celebrating the 60th birthday of Professor Michael Ortiz, to whom this book is dedicated. His work has long been recognized as pioneering and is a continuing source of inspiration for ma...

Michael Faraday en die letterlike lesing van twee ‘boeke’ van God: 'n Gevallestudie oor verhouding tussen geloof en wetenskap1

Directory of Open Access Journals (Sweden)

M. Elaine Botha

1993-03-01

Full Text Available The cognitive historical approach to the history of science provides a methodological approach which makes it possible to take into account most of the factors which were constitutive in the formation of scientific meaning in scientific concept formation. In this article this approach is linked with a methodology of metaphorical hermeneutics in order to determine the role played by religious factors in the meaning of scientific concepts. Contrary to traditional approaches in which religious factors are primarily seen as confessional in nature, the term religious is utilized here to identify those absolute presuppositions which fulfil a controlling or regulative function in scientific concept formation and theorizing. 'This approach is applied to a case study of the relationship of faith and science in the work of the nineteenth century British physicist, Michael Faraday. This approach provides an analysis of the change in conceptual structure which the concept of force undergoes in a transition from a mechanistic to a dynamistic metaphysical framework. In this analysis attention is also given to the distinction between confessional religious factors, metaphysical frameworks, meta-scientific principles and theories.

Nobody Knows My Name: The Masquerade of Mourning in the Early 1980s Artistic Productions of Michael Jackson and Prince

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Pochmara Anna

2017-12-01

Full Text Available The article analyses Michael Jackson’s album Thriller and Prince’s movie Purple Rain. We explore their camp aesthetics and their recasting of the cultural representations of the black male. Jackson’s and Prince’s performative personas are both liberatory and burdened with the received cultural scripts of black masculinity. We claim that their employment of camp is political rather than escapist and depoliticized. Camp serves them as a platform to mourn the cultural displacement of the black male body in a postslavery America. In particular, the two artists distance themselves from the extensive ideological and physical pressures exerted on the black male body in the early 1980s. As a result, their performances are complexly de-Oedipalized. Prince in Purple Rain refuses to assume the patriarchal position of the Father. Analogously, Jackson fashions himself as a Peter Pan-like eternal adolescent who never makes his final identification as either heterosexual or LGBTQ desiring agent. In the coda to the article, we reach beyond the 1980s to explore a more flexible approach to camp in the artistic output of twenty-first-century African American performers of Queercore and Afrofuturist scenes, which were partially enabled by Jackson’s and Prince’s performances.

Linnadisaini lõpp(eesmärgid) / Michael Sorokin

Index Scriptorium Estoniae

Sorokin, Michael

2008-01-01

Autori arvates on linnadisain (urban design) jõudnud tupikusse. Ta on järjest vähem võimeline leidma leidlikke lahendusi linnade ja linnakodanike morfoloogilistele, funktsionaalsetele ja inimlikele vajadustele. Samal ajal kui ülesanded muutuvad keerukamaks ja pakilisemaks, on eriala peavoolustunud, muutudes potensiaalselt laiast ja lootusrikkast kontseptuaalsest kategooriast järjest enam paindumatuks, piiravaks ja igavaks vanade tavade järgimiseks

Regele Mihai între „est” și „vest”. Percepții, poziționări, simboluri (King Michael between east and west. Perceptions, positionings, symbols

Directory of Open Access Journals (Sweden)

Alexandru MURARU

2015-12-01

Full Text Available The article investigates three strategic directions within the political perceptions of Romanian King Michael involving the East/West paradigm. The article will try to highlight the main positioning, both in Exile and the complicated recent history, immediately after the December 1989 events. King Michael’s relations with Western powers and attitude throughout Romania after 1989, the fate of Bessarabia as a direct „confrontation” between East -West and the significances of the „August 23” Act in reshaping the post-revolutionary memorial debate, represent three fundamental perspectives in understanding the „East” and „West” thinking of the Romanian monarch. These three themes, rich in meanings, have three major connotations: moral, geographic and memorials. Each of them are explained and decrypted with many examples, quotes, and historical and geographical references.

A small stone column of the altar screen from the treasures of St Archangel Michael's monastery in Prevlaka

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Crnčević Dejan

2013-01-01

Full Text Available Amongst exhibited fragments of carved stone decorations in the monastery of St Archangel Michael in Prevlaka, Boka Kotorska, situated on the ground floor of the monastery's accommodation quarters, there is a segment of stone liturgical furnishings which is, among other things, distinguished by its monumental dimensions, the high level of its craftsmanship, and the important artistic value of its carved decorations. This small stone column was found by chance as a surface-level find on the neighbouring island of St Gavrilo. This stone column is made from a monolithic piece of high- quality, light-grey marble. It is 96 cm in height, 20 cm wide at the front, 18.5 cm wide at the side, and 13cm wide at the rear. These dimensions indicate that the fragment has the form of an elongated hexahedron, with sides of unequal width. Only the front of this stone fragment is marked with relief decorations, comprising a regularly shaped two-part curled sprouting vine. Moving with its undulating rhythm, its arc defines a space in which is located the central motif of the decoration. This comprises the motif of a bud in the form of stylised crinoline flower, composed of two lateral leaves with a pronounced bulge in the middle. These tightly bent lateral leaves with sharp ends, together with the root of the formed shoot, leave an empty space filled with an offshoot in the form of a regularly formed volute. The left lateral side of the stone column is marked by a long but relatively shallow channel, created around its axis, with a width of 7.5 cm. Its rear side is divided by its own height into two vertical fields, of almost the same width - 6 and 7 cm respectively - one slightly elevated compared to the other. The right lateral side of the column is slanted and only lightly sculptured. On the upper surface of the pillar, a relatively shallow circular hole with a small span is visible, intended as a connection point for other segments that would have been placed on

Delayed entry into first marriage and marital stability: Further evidence on the Becker-Landes-Michael hypothesis

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Evelyn Lehrer

2013-09-01

Full Text Available BACKGROUND In their pioneering research, Becker, Landes, and Michael (1977 found that beyond age 30 there is a positive relationship between women's age at first marriage and marital instability. They interpreted this finding as a "poor-match effect" emerging when the biological clock begins to tick. OBJECTIVE Our objective was to ascertain with more recent data whether or not there is evidence of a poor match effect and if so, whether it is associated with higher marital instability. METHODS We used data on non-Hispanic white women from the 2006-2010 National Surveys of Family Growth (NSFG (N = 3,184. RESULTS We found evidence of the existence of a poor-match effect: women who delay marriage disproportionately make unconventional matches, which are generally associated with high marital instability. We also found, however, that their unions are very solid. Both of these results were consistent with earlier findings for the 1995 and 2002-2003 NSFG cycles. In attempting to explain this puzzle, we proposed and tested competing hypotheses. We found that the destabilizing effects associated with indicators of unconventional matches are also present in marriages contracted late, but are dwarfed by the stabilizing influences associated with higher levels of education and older ages. CONCLUSIONS This paper contributes to our understanding of the determinants of marital instability and the poor match effect by providing a new interpretation for the puzzle described above. COMMENTS Our findings have implications for analyses of changes over time in the extent of positive assortative mating in the marriage market, and for the extensive literature showing that heterogamy in traits that are complementary in the context of marriage is destabilizing -- heterogamous marriages contracted at a late age are likely to be stable.

D/B/F 98: Final Report Of the AIAA Student Aircraft Design, Build & Fly Competition

Science.gov (United States)

1998-01-17

Melissa Clarke Airframe, CAD Pieter-Jan Dejaeghere Electrics, Motor Table 2.2. Project Schedule & Timing Milestone Planned Date (month /week) Actual...Shoemaker, Group Head Tom Scarberry Group Flight Test Members: Pete Cooke, Group Head Michael Benkert Joe Giordano Brandon Richards Faculty

77 FR 6743 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Science.gov (United States)

2012-02-09

... Standards (NAAQS) On or After November 15, 1992,'' Memorandum from Michael H. Shapiro, Acting Assistant....077 0.064 Lake Hammond (180892008) 0.075 0.077 0.068 0.065 0.069 0.073 0.067 Porter Valparaiso...

Beyond cyborg metapathography in Michael Chorost’s Rebuilt to World Wide Mind: Introducing “morphos” as a rhetorical concept in cyborgography

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Kevin A. Thayer

2013-08-01

Full Text Available This essay introduces the rhetorical concept of “morphos”, a dimension of ethos, in the context of cyborg self-transformation and cyborg storytelling. Focusing on the cyborg storytelling of Michael Chorost, a cochlear implant user and futurist, this essay applies "morphos" to develop an argument about the changing capabilities and changing stories of living cyborg authors. Using rhetorical concepts to illuminate his self-transformation and narrative constructions, this essay analyzes Chorost’s two books: Rebuilt: How Becoming Part Computer Made Me More Human; and, World Wide Mind: The Coming Integration of Humanity, Machines, and the Internet. Chorost’s first book, Rebuilt, is an autobiographical account of his journey from deafness to cochlear implant hearing and his quest for community. He completes his journey of self-transformation using Haraway’s Cyborg Manifesto and Caidin’s Cyborg as narrative tools. Rebuilt can be defined as a cyborg metapathography, identifying rhetorical features of Chorost’s cyborg storytelling. Chorost’s second book, World Wide Mind, is both autobiographical and theoretical. This rhetorical shift in the context of his changing physical, perceptual, and cognitive capabilities, and his changing ethos, is significant because it opens the way for a new hybrid language combining the spoken/written and digital code.

Stereoselective synthesis of diazaspiro[5.5]undecane derivatives via base promoted [5+1] double Michael addition of N,N-dimethylbarbituric acid to diaryliedene acetones

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Mohammad Shahidul Islam

2017-01-01

Full Text Available The nitrogen containing spiro-heterocycle is one of the privileged synthetic motif that constitutes various naturally occurring molecules and displays a broad range of pharmaceutical and biological activities. A new methodology was developed for the synthesis of 2,4-diazaspiro[5.5]undecane-1,3,5,9-tetraones spiro-heterocyclic derivatives via cascade cyclization of [5+1] double Michael addition reaction of N,N-dimethylbarbituric acid with the derivatives of diaryldivinylketones in the presence of diethylamine at ambient temperature. The developed protocol is highly capable of furnishing diazaspiro[5.5]undecane derivatives 3a–m in excellent yields (up to 98%, from easily accessible symmetric and non-symmetric divinylketones 2a–m, containing aryl and heteroaryl substituents. The diazaspiro-heterocyclic structure was mainly elucidated by NMR and X-ray crystallographic techniques. The single-crystal X-ray studies revealed that, the cyclohexanone unit of spirocycles often prefers a chair conformation rather than twisted conformation. The intermolecular hydrogen bonding and CArH⋯π, π–π stacking interactions driving forces are mainly responsible for the crystal packing.

Thioredoxin reductase from barley: Structure, recognition of thioredoxin, protein engineering and catalytic mechanism

DEFF Research Database (Denmark)

Kirkensgaard, Kristine Groth

eukaryotes but appears to be absent in most prokaryotes. The crystal structure of HvTrxh2 covalently bound to the barley α‐amylase/subtilisin inhibitor (BASI, Maeda et al., 2006a), allowed comparison of the molecular features involved in the interactions between HvTrxh2 and its electron donor (NTR...... of HvNTR2 and HvTrxh2 was built, using the structure of Escherichia coli NTR covalently bound to Trx (EcNTR:EcTrx) as a template (Lennon et al., 2000). The model provides new insight into how eukaryotic LMW NTRs in general bind Trx and suggests major differences in the NTR:Trx binding interface of Hv...

Intelligent Design Creationism: The New Kid on the Block

Science.gov (United States)

Scott, Eugenie C.

2000-03-01

Traditionally, the antievolution movement has been characterized by biblical literalists who hold that the universe (including living things) was created in its present form and has not appreciably changed since that creation event, which in the most familiar version, "young earth" creationism (YEC), occurred about 10,000 years ago. The YECs primarily are associated with not-for-profit organizations such as the Institute for Creation Research and Answers in Genesis. Now there is a "new kid on the [antievolutionist] block": Intelligent Design Creationism (IDC). IDC updates William Paley's 1801 "Argument from Design" that structural complexity requires an omniscient designer, with examples from biochemistry and cell biology. Unlike YEC, IDC's most prominent practitioners are academics associated with secular universities, such as lawyer Phillip Johnson of UC- Berkeley, and biochemist Michael Behe of Lehigh University. Like YECs, IDCs stress alleged "weaknesses" in evolution more than positive evidence for their position. IDCs avoid the Big Bang, the age of the Earth, the speed of light, and most other cosmological issues, but are very concerned with "disproving" biological evolution, the inference that living things shared common ancestry. They also argue that evolution is inherently anti-religious. Perhaps most disturbingly, they propose that supernatural explanations be allowed into science. Although the most prominent IDCs are based at secular universities, they produce little IDC scholarship. Refereed scholarly articles promoting IDC have been lacking, though books and articles for the general public and newspaper opinion/editorial pieces, appear in great quantity. IDC books are being used in philosophy of science, science studies, and other non-science courses where students may be misled into thinking that evolution is scientifically a "theory in crisis."

Design, Synthesis and Evaluation of Ribose-modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors

Science.gov (United States)

Hu, Xiuqin; Wang, Disha; Tong, Yi; Tong, Linjiang; Wang, Xia; Zhu, Lili; Xie, Hua; Li, Shiliang; Yang, You; Xu, Yufang

2017-11-01

The synthesis of a series of ribose-modified anilinopyrimidine derivatives was efficiently achieved by utilizing DBU or tBuOLi-promoted coupling of ribosyl alcohols with 2,4,5-trichloropyrimidine as key step. Preliminary biological evaluation of this type of compounds as new EGFR tyrosine kinase inhibitors for combating EGFR L858R/T790M mutant associated with drug resistance in the treatment of non-small cell lung cancer revealed that 3-N-acryloyl-5-O-anilinopyrimidine ribose derivative 1a possessed potent and specific inhibitory activity against EGFR L858R/T790M over WT EGFR. Based upon molecular docking studies of the binding mode between compound 1a and EGFR, the distance between the Michael receptor and the pyrimidine scaffold is considered as an important factor for the inhibitory potency and future design of selective EGFR tyrosine kinase inhibitors against EGFR L858R/T790M mutants.

Using customer-focused research and design to build a self-service online store: a case study

Directory of Open Access Journals (Sweden)

Ahmadi MB

2013-02-01

Full Text Available Michael B Ahmadi,1 William Trefzger,2 Rich Morey,1 Ileana Quintas31Substance Abuse and Mental Health Services Administration, Rockville, 2Centers for Medicare and Medicaid Services, Baltimore, 3IQ Solutions, Inc, Rockville, MD, USAAbstract: American government information centers need to be responsive to an increasingly customer driven information environment while ensuring the sustainability of operations. Enhanced self-service options offer one avenue for addressing both of these needs. This article presents a case study of how the US Substance Abuse and Mental Health Services Administration used extensive stakeholder research and a customer-centric design to reframe its service model by building a self-service online store that integrates access to more than 1300 behavioral health publications previously housed in two separate clearinghouses. The redesigned Substance Abuse and Mental Health Services Administration Store offers users a modern e-commerce website that not only helps customers find, order, download, and share products, but also encourages serendipitous content exploration, which has led to increased orders containing both substance abuse and mental health publications.Keywords: customer research, taxonomy, usability testing, web analytics, web design

The ethical Dilemma of lifestyle change: designing for sustainable schools and sustainable citizenship

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Andrea Wheeler

2009-06-01

Full Text Available This paper explores how participation and sustainability are being addressed by architects within the Building Schools for the Future (BSF programme in the UK. The intentions promoted by the programme are certainly ambitious, but the ways to fulfil these aims are ill-explored. Simply focusing on providing innovative learning technologies, or indeed teaching young people about physical sustainability features in buildings, will not necessarily teach them the skills they will need to respond to the environmental and social challenges of a rapidly changing world. However, anticipating those skills is one of the most problematic issues of the programme. The involvement of young people in the design of schools is used to suggest empowerment, place-making and to promote social cohesion but this is set against government design literature which advocates for exemplars, standard layouts and best practice, all leading to forms of standardisation. The potentials for tokenistic student involvement and conflict with policy aims are evident. This paper explores two issues: how to foster in young people an ethic towards future generations, and the role of co-design practices in this process. Michael Oakeshott calls teaching the conversation of mankind. In this paper, I look at the philosophy of Hannah Arendt, Emmanuel Levinas, Maurice Merleau-Ponty and Luce Irigaray to argue that investigating the ethical dilemmas of the programme through critical dialogue with students offers an approach to meeting government objectives, building sustainable schools, and fostering sustainable citizenship.

The Effect of Prosthetic Socket Interface Design on Socket Comfort, Residual Limb Health, and Function for the Transfemoral Amputee

Science.gov (United States)

2017-10-01

analysis. Mentoring undergraduate student. Name: Michael Porter Project Role: Undergraduate student, Mechanical Engineering Research Identifier...the PD/PI(s) or senior /key personnel since the last reporting period? No. What other organizations were involved as partners

The Art of Displacement: Designing Experiential Systems and Transverse Epistemologies as Conceptual Criticism

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Rolf Hughes

2014-07-01

Full Text Available With architects and designers increasingly facing problems that are neither predictable nor simple but highly complex, a particular synthesis of design intelligence and creativity is required. If the art of being a professional is becoming ‘the art of managing complexity’, what are the ‘boundaries’ of professional practice? ‘Trans-disciplinarity’, for example, requires liminal or neither/nor thinking (thus ‘boundary concepts’ remain a core concern. A concern with boundaries and ‘edges’ implies in turn a concern with ‘relationality’ (i.e. how we establish relations, positions, borders between different disciplinary priorities and methods and thence a problem that affects how we think of disciplinarity, interdisciplinarity, networks of various kinds, and trans-disciplinarity – that of ‘substance’, ‘content’ or ‘matter’.This paper subjects design research, theory and practice to transverse epistemologies, attempting a ‘flow of transformations’ via such themes as authorship, remediation, smuggling, disruptive innovation, performative knowledge, and gesture versus identity. It brings together an ars combinatoria of conceptual criticism, trans-disciplinary practice as ‘disruptive innovation’, Michael Speaks’s notion of ‘design intelligence’ and Margaret Boden’s three types of creativity – combinatorial, exploratory, and transformational – seeking thereby to suggest new structures that might yield ‘transdisciplines’. Departing from two separate points – Bruno Latour’s call for ‘earthly accounts of buildings and design processes’ and Jack Burnham’s identification of a paradigm shift from an ‘object-oriented’ to a ‘systems-oriented’ culture – the paper describes the formation of a new interdisciplinary practice, experience design (the design of meaningful experience across time, as a form of ‘epistemological Conceptualism’. This prioritises critical thinking and

Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

Energy Technology Data Exchange (ETDEWEB)

Xue, Xiaoyu; Yu, Hongwei; Yang, Haitao; Xue, Fei; Wu, Zhixin; Shen, Wei; Li, Jun; Zhou, Zhe; Ding, Yi; Zhao, Qi; Zhang, Xuejun C.; Liao, Ming; Bartlam, Mark; Rao, Zihe (SCAU); (Tsinghua); (Chinese Aca. Sci.)

2008-07-21

Coronaviruses (CoVs) can infect humans and multiple species of animals, causing a wide spectrum of diseases. The coronavirus main protease (M{sup pro}), which plays a pivotal role in viral gene expression and replication through the proteolytic processing of replicase polyproteins, is an attractive target for anti-CoV drug design. In this study, the crystal structures of infectious bronchitis virus (IBV) MP{sup pro} and a severe acute respiratory syndrome CoV (SARS-CoV) M{sup pro} mutant (H41A), in complex with an N-terminal autocleavage substrate, were individually determined to elucidate the structural flexibility and substrate binding of M{sup pro}. A monomeric form of IBV M{sup pro} was identified for the first time in CoV M{sup pro} structures. A comparison of these two structures to other available M{sup pro} structures provides new insights for the design of substrate-based inhibitors targeting CoV M{sup pro}s. Furthermore, a Michael acceptor inhibitor (named N3) was cocrystallized with IBV M{sup pro} and was found to demonstrate in vitro inactivation of IBV M{sup pro} and potent antiviral activity against IBV in chicken embryos. This provides a feasible animal model for designing wide-spectrum inhibitors against CoV-associated diseases. The structure-based optimization of N3 has yielded two more efficacious lead compounds, N27 and H16, with potent inhibition against SARS-CoV M{sup pro}.

The emotional importance of key: do Beatles songs written in different keys convey different emotional tones?

Science.gov (United States)

Whissel, R; Whissel, C

2000-12-01

Lyrics from 155 songs written by the Lennon-McCartney team were scored using the Dictionary of Affect in Language. Resultant scores (pleasantness, activation, and imagery of words) were compared across key signatures using one way analyses of variance. Words from songs written in minor keys were less pleasant and less active than those from songs written in major keys. Words from songs written in the key of F scored extremely low on all three measures. Lyrics from the keys of C, D, and G were relatively active in tone. Results from Dictionary scoring were compared with assignments of character to keys made more than one century ago and with current musicians' opinions.

Pourquoi le « Disque Blanc » des Beatles est-il Blanc ?

Directory of Open Access Journals (Sweden)

Bernard Gensane

2006-02-01

Full Text Available Dans « Strawberry Fields Forever » (février 1967, John Lennon prévient, dans une perspective postmoderne, que la représentation artistique est impossible car « nothing is real ». Au même moment, Paul McCartney propose, avec « Penny Lane » (février 1967, une des plus troublantes définitions de ce qu’est la représentation artistique : « And though she feels as if she’s in a play / She is anyway ». Que se passe-t-il, en effet, lorsque l’art est sciemment accepté comme un faux-semblant à la foi...

Design and Construction of a High Vacuum Surface Analysis Instrument to Study Chemistry at Nanoparticulate Surfaces

Science.gov (United States)

2011-04-21

White, Amy Weber, Simon Taxel, Hikmat Daghestani, Chris Stetson, Michael Mobilia, and the Blacksburg Rugby Football Club. Finally, I would...Background and Motivation ........................................................................................... 1 1.1. Introduction...Background and Motivation 1.1 Introduction The decontamination of chemical warfare agents is of great importance to both the military and civilian

Counterpublic health and the design of drug services for methamphetamine consumers in Melbourne.

Science.gov (United States)

Duff, Cameron; Moore, David

2015-01-01

This article is interested in how notions of the 'public' are conceived, marshalled and enacted in drug-treatment responses to methamphetamine use in Melbourne, Australia. After reviewing qualitative data collected among health-care providers and methamphetamine consumers, we draw on the work of Michael Warner to argue that services for methamphetamine consumers in Melbourne betray ongoing tensions between 'public' and 'counterpublic' constituencies. Our analysis indicates that these tensions manifest in two ways: in the management of 'street business' in the delivery of services and in negotiating the meaning of health and the terms of its restoration or promotion. Reflecting these tensions, while the design of services for methamphetamine consumers is largely modelled on public health principles, the everyday experience of these services may be more accurately characterised in terms of what Kane Race has called 'counterpublic health'. Extending Race's analysis, we conclude that more explicit focus on the idea of counterpublic health may help local services engage with methamphetamine consumers in new ways, providing grounds for novel outreach, harm-reduction and treatment strategies. © The Author(s) 2014.

A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson’s Research

Directory of Open Access Journals (Sweden)

Marco A. S. Baptista

2013-11-01

Full Text Available Progress in Parkinson’s disease (PD research and therapeutic development is hindered by many challenges, including a need for robust preclinical animal models. Limited availability of these tools is due to technical hurdles, patent issues, licensing restrictions and the high costs associated with generating and distributing these animal models. Furthermore, the lack of standardization of phenotypic characterization and use of varying methodologies has made it difficult to compare outcome measures across laboratories. In response, The Michael J. Fox Foundation for Parkinson’s Research (MJFF is directly sponsoring the generation, characterization and distribution of preclinical rodent models, enabling increased access to these crucial tools in order to accelerate PD research. To date, MJFF has initiated and funded the generation of 30 different models, which include transgenic or knockout models of PD-relevant genes such as Park1 (also known as Park4 and SNCA, Park8 (LRRK2, Park7 (DJ-1, Park6 (PINK1, Park2 (Parkin, VPS35, EiF4G1 and GBA. The phenotypic characterization of these animals is performed in a uniform and streamlined manner at independent contract research organizations. Finally, MJFF created a central repository at The Jackson Laboratory (JAX that houses both non-MJFF and MJFF-generated preclinical animal models. Funding from MJFF, which subsidizes the costs involved in transfer, rederivation and colony expansion, has directly resulted in over 2500 rodents being distributed to the PD community for research use.

Michael Nyman, (filmi)muusika Superman / Michael Nyman ; interv. Harry Liivrand

Index Scriptorium Estoniae

Nyman, Michael, 1944-

2000-01-01

M. Nyman (s. 1944) oma uudisteosest "The Commissar Vanishes" (multimeediana kujundas C. Kondek, teose aluseks D. Kingi raamat Stalini ajal A. Rodtšenko poolt retušeeritud ja ülemaalitud kommunistide fotodest), koostööst P. Greenawayga. H. Liivrand ja A. Remme M. Nymanist, tema loomingust

Review of "Handbook of Human Factors in Medical Device Design", edited by Matthew B. Weinger, Michael E. Wiklund and Daryle J. Gardner-Bonneau, Assistant Editor Loir M. Kelly

Directory of Open Access Journals (Sweden)

Gaev Jonathan A

2011-06-01

Full Text Available Abstract Human factors is the study of the relationship between people and devices or systems. The goal of considering human factors in the design of medical devices is to create devices that take into consideration the way people use technology and process information to create a man-machine interface that leads to the best possible performance. This text describes the significant aspects of human factors issues related to medical device design. It is well written and is useful for medical device designers and for others who use or evaluate medical equipment.

Intelligent Design and the Creationism/Evolution Controversy

Science.gov (United States)

Scott, E. C.

2004-12-01

"Intelligent Design" (ID) is a new form of creationism that emerged after legal decisions in the 1980s hampered the inclusion of "creation science" in the public school curriculum. To avoid legal challenge, proponents claim agnosticism regarding the identity of the intelligent agent, which could be material (such as highly intelligent terrestrials) or transcendental (God). ID consists of a scientific/scholarly effort, and a politico-religious movement of "cultural renewal." Intelligent design is supposedly detectable through the application of Michael Behe's "irreducible complexity" concept and/or William Dembski's concept of "complex specified information". ID's claims amount to, first, that "Darwinism" (vaguely defined) is incapable of providing an adequate mechanism for evolution, and second (subsequently), that evolution did not occur. Although scientific ideas not infrequently are slow to be accepted, in the 20 years since ID appeared, there is no evidence of it being used to solve problems in biology. Even if the scientific/scholarly part of ID has been a failure, the "cultural renewal" part of ID has been a success. This social and political aspect of ID seeks "restoration" of a theistic sensibility in American culture to replace what supporters consider an overemphasis on secularism. In the last few years, in several states, legislators have introduced legislation promoting ID (to date, unsuccessfully) and an addendum to the 2001 federal education bill conference committee report (the "Santorum amendment") is being used to promote the teaching of ID in public schools. Perhaps because ID has no actual content other than antievolutionism, ID proponents contend that pre-college teachers should teach wweaknesses of evolutionw or "evidence against evolutionw - largely warmed-over arguments from creation science - even though professional scientists do not recognize these as valid scientific claims.

Design, synthesis and cellular metabolism study of 4'-selenonucleosides.

Science.gov (United States)

Yu, Jinha; Sahu, Pramod K; Kim, Gyudong; Qu, Shuhao; Choi, Yoojin; Song, Jayoung; Lee, Sang Kook; Noh, Minsoo; Park, Sunghyouk; Jeong, Lak Shin

2015-01-01

4'-seleno-homonucleosides were synthesized as next-generation nucleosides, and their cellular phosphorylation was studied to confirm the hypothesis that bulky selenium atom can sterically hinder the approach of cellular nucleoside kinase to the 5'-OH for phosphorylation. 4'-seleno-homonucleosides (n = 2), with one-carbon homologation, were synthesized through a tandem seleno-Michael addition-SN2 ring cyclization. LC-MS analysis demonstrated that they were phosphorylated by cellular nucleoside kinases, resulting in anticancer activity. The bulky selenium atom played a key role in deciding the phosphorylation by cellular nucleoside kinases. [Formula: see text].

Wedging Creationism into the Academy

Science.gov (United States)

Forrest, Barbara; Branch, Glenn

2005-01-01

In 1999, William Dembski became director of the newly established Michael Polanyi Center at Baylor University, thanks to the support of Baylor's president Robert Sloan. The center was, as Dembski observed, "the first intelligent design think tank at a research university." As such, it fulfilled a crucial objective of the "intelligent design"…

Competitiveness Implications of Environmental Regulations: Case Studies (1992- 1997)

Science.gov (United States)

This collection of reports is part of a series of case studies designed to examine Michael Porter’s hypothesis that innovative companies responding to environmental regulation can create competitive advantage through lower costs or higher sales.

¿Por qué existe el Estado y no más bien la anarquía? (El anarco-comunitarismo de Michael Taylor

Directory of Open Access Journals (Sweden)

Rivera, Juan Antonio

1996-04-01

Full Text Available Not available.

Se expone la perspectiva anarco-comunitarísta de Michael Taylor, y se la distingue de la anarco-capitalista de autores como Murray Rothbard, David Friedman o, en menor medida, Robert Nozick. El anarco- comunitarismo de Taylor está sólidamente asentado en la teoría de juegos; concretamente, en los análisis dinámicos del Dilema del Prisionero. Sobre la base de estos análisis, a los que el propio autor ha hecho contribuciones sustanciales, se pone de relieve la inviabilidad práctica de una anarquía perfecta, sin controles sociales externos. Pero Taylor muestra que hay, con todo, lugar para un orden social sostenido en controles informales y ampliamente descentralizados, es decir, fundado en vínculos comunitarios, y que ésta ha sido la solución al problema del orden social durante la mayor parte de la historia de la especie. Se discuten luego las circunstancias que presumiblemente dieron lugar a la crisis y obsolescencia de la solución anarco-comunitarista y su sustitución por la respuesta institucional basada en la presencia del Estado. Se concluye el escrito ensalzando los méritos teóricos de Taylor pero poniendo en duda la validez de los presupuestos valorativos que animan sus modestas proposiciones de cambio social.

MONTAGE: A Methodology for Designing Composable End-to-End Secure Distributed Systems

Science.gov (United States)

2012-08-01

and verification, from PSOS [NF03] to the recent seL4 [KEH+09]. While they make considerable progress toward high-assurance OS, these works are not...of the specification itself. Examples include the seL4 microkernel work by Klein et al. [KEH+09], which presents the experience of formally proving...David Cock, Philip Derrin, Dhammika Elkaduwe, Kai Engelhardt, Rafal Kolanski, Michael Norrish, Thomas Sewell, Harvey Tuch, and Simon Winwood. sel4

Synthesis, characterization and the release kinetics of antiproliferative agents from polyamidoamine conjugates

CSIR Research Space (South Africa)

Aderibigbe, BA

2015-01-01

Full Text Available Polyamidoamine conjugates containing curcumin and bisphosphonate were synthesized via a one-pot aqueous phase Michael addition reaction. In the design of the conjugate, bisphosphonate formed an integral part of the polymer carrier backbone. Curcumin...

Michael Bahl | NREL

Science.gov (United States)

theoretical mathematics, Western New England University, Springfield, MA B.S. in computer science, University Prior Work Experience Founder, Mobile Makes Sense Senior IT Specialist, IBM Graduate Teaching Assistant

Michael Seibert | NREL

Science.gov (United States)

. Chair, Alcohol Sources and Uses Session, International Solar Energy Society Meeting, 1981. Member Apparatus for Rapid Biohydrogen Phenotypic Screening of Microorganisms Using a Chemochromic Sensor," Biohydrogen Phenotypic Screening of Microorganisms Using a Chemochromic Sensor," U.S. Patent # 6,448,068

Michael Resch | NREL

Science.gov (United States)

applications along with analytical chemistry expertise. From October 2016 to September 2017, Dr. Resch was on Stover Lignin," ACS Sustainable Chemistry and Engineering (2016) "Interrelationships Between ) "Lignin Depolymerization by Fungal Secretomes and a Microbial Sink," Green Chemistry (2016

A designated centre for people with disabilities operated by St Michael's House, Dublin 9

LENUS (Irish Health Repository)

Flinn, AM

2018-02-01

Diagnosis of Kawasaki Disease (KD) can be challenging due to lack of a diagnostic test, and some children present with ‘incomplete’ KD when not all diagnostic criteria are met. Treatment with intravenous immunoglobulin (IVIG) and aspirin reduces the risk of coronary artery complications. There is sub-group of patients who are resistant to IVIG\\/aspirin therapy and are at increased risk of complications. Recent evidence suggests that additional treatment of this high-risk group with corticosteroids is beneficial in reducing this risk. We examine the treatment and coronary artery outcomes, by retrospective review of medical records, of a cohort of 32 paediatric patients with KD admitted to a single Irish tertiary centre from January 2010-December 2014. Twenty-eight percent of patients (9\\/32) had an incomplete diagnosis of KD; these patients received IVIG later compared to those with a complete KD diagnosis. 15\\/32 (47%) had abnormal echocardiogram findings in the acute phase, 8\\/32 (25%) had echocardiogram abnormalities at 6-week follow-up, and 4\\/32 (12.5%) had persisting abnormalities. This study highlights the potential for adverse outcome in KD, the difficulty in diagnosis in ‘incomplete’ cases, and the need to identify children at higher risk for adverse outcome where adjunctive therapies would be most beneficial.

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LENUS (Irish Health Repository)

McGrath, Bridget

2012-01-01

This study explored registered psychiatric nurses\\' (RPNs\\') interactions and level of empathy towards service users with a diagnosis of borderline personality disorder (BPD). A qualitative approach was used, and 17 RPNs were interviewed using a semistructured interview schedule incorporating the "staff-patient interaction response scale" (SPIRS). Four themes emerged following data analysis: "challenging and difficult," "manipulative, destructive and threatening behaviour," "preying on the vulnerable resulting in splitting staff and other service users," and "boundaries and structure." Additionally, low levels of empathy were evident in the majority of participants\\' responses to the SPIRS. The findings provide further insight on nurses\\' empathy responses and views on caring for service users with BPD and further evidence for the need for training and education for nurses in the care of service users diagnosed with BPD.

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LENUS (Irish Health Repository)

2010-01-01

ABSTRACT: BACKGROUND: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineering of GRNs). However, the nature of these data has made this process very difficult. At the moment, several methods of discovering qualitative causal relationships between genes with high accuracy from microarray data exist, but large scale quantitative analysis on real biological datasets cannot be performed, to date, as existing approaches are not suitable for real microarray data which are noisy and insufficient. RESULTS: This paper performs an analysis of several existing evolutionary algorithms for quantitative gene regulatory network modelling. The aim is to present the techniques used and offer a comprehensive comparison of approaches, under a common framework. Algorithms are applied to both synthetic and real gene expression data from DNA microarrays, and ability to reproduce biological behaviour, scalability and robustness to noise are assessed and compared. CONCLUSIONS: Presented is a comparison framework for assessment of evolutionary algorithms, used to infer gene regulatory networks. Promising methods are identified and a platform for development of appropriate model formalisms is established.

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McGuinness, Martina

2009-08-01

A number of toxic synthetic organic compounds can contaminate environmental soil through either local (e.g., industrial) or diffuse (e.g., agricultural) contamination. Increased levels of these toxic organic compounds in the environment have been associated with human health risks including cancer. Plant-associated bacteria, such as endophytic bacteria (non-pathogenic bacteria that occur naturally in plants) and rhizospheric bacteria (bacteria that live on and near the roots of plants), have been shown to contribute to biodegradation of toxic organic compounds in contaminated soil and could have potential for improving phytoremediation. Endophytic and rhizospheric bacterial degradation of toxic organic compounds (either naturally occurring or genetically enhanced) in contaminated soil in the environment could have positive implications for human health worldwide and is the subject of this review.

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Day, Mary Rose

2015-03-02

Self-neglect is a worldwide and serious public health issue that can have serious adverse outcomes and is more common in older people. Cases can vary in presentation, but typically present as poor self-care, poor care of the environment and service refusal. Community nurses frequently encounter self-neglect cases and health and social care professionals play a key role in the identification, management and prevention of self-neglect. Self-neglect cases can give rise to ethical, personal and professional challenges. The aim of this article is to create a greater understanding of the concept of self-neglect among community nurses.

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Fawsitt, Christopher G

2013-01-01

Elective repeat caesarean delivery (ERCD) rates have been increasing worldwide, thus prompting obstetric discourse on the risks and benefits for the mother and infant. Yet, these increasing rates also have major economic implications for the health care system. Given the dearth of information on the cost-effectiveness related to mode of delivery, the aim of this paper was to perform an economic evaluation on the costs and short-term maternal health consequences associated with a trial of labour after one previous caesarean delivery compared with ERCD for low risk women in Ireland.

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Owens, P

2015-01-01

Single stage en bloc abdominoperineal resection and sacrectomy, with a myocutaneous flap closure is a relatively uncommon procedure. Our case study of a 77 year old man with a locally invasive rectal adenocarcinoma highlights the complex intraoperative management of such a patient.

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Knox, Shane

2015-01-01

In November 2013, the Irish Regulator for emergency medical technicians (EMTs) introduced the first mandatory requirement for registrants to demonstrate evidence of continuous professional development (CPD)\\/continuous professional competence (CPC). This qualitative study assessed the experience of practitioners with CPC-related materials provided to them by the Regulator in addition to identifying perceived or encountered practical challenges and suggested improvements six months following introduction of the requirement.

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Ferris, Helena

2016-04-28

Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population worldwide, with respiratory disease remaining the most relevant source of morbidity and mortality. Computed tomography (CT) is frequently used for monitoring disease complications and progression. Over the last fifteen years there has been a six-fold increase in the use of CT, which has lead to a growing concern in relation to cumulative radiation exposure. The challenge to the medical profession is to identify dose reduction strategies that meet acceptable image quality, but fulfil the requirements of a diagnostic quality CT. Dose-optimisation, particularly in CT, is essential as it reduces the chances of patients receiving cumulative radiation doses in excess of 100 mSv, a dose deemed significant by the United Nations Scientific Committee on the Effects of Atomic Radiation. This review article explores the current trends in imaging in CF with particular emphasis on new developments in dose optimisation.

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Evans, David S.

2016-01-01

n order to gain a measure of the health and wellbeing of staff in the Health and Wellbeing Division a survey was undertaken in late 2015 with results contained in this report. It highlights the areas that we are doing well in and identifies a number of areas where improvements are needed. The results and suggestions given provide a benchmark as to the current health and wellbeing status of those in our Division and pave the way for a set of recommendations which will be delivered through the action plan currently being developed. As a starting point and in recognition of the fact that many of our staff are based in other cross divisional worksites, the Staff Health and Wellbeing Funding Initiative 2016 was introduced.

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O'Driscoll, Jeremiah

2011-06-09

Abstract Background Ankle joint sprain and the subsequent development of chronic ankle instability (CAI) are commonly encountered by clinicians involved in the treatment and rehabilitation of musculoskeletal injuries. It has recently been advocated that ankle joint post-sprain rehabilitation protocols should incorporate dynamic neuromuscular training to enhance ankle joint sensorimotor capabilities. To date no studies have reported on the effects of dynamic neuromuscular training on ankle joint positioning during landing from a jump, which has been reported as one of the primary injury mechanisms for ankle joint sprain. This case report details the effects of a 6-week dynamic neuromuscular training programme on ankle joint function in an athlete with CAI. Methods The athlete took part in a progressive 6-week dynamic neuromuscular training programme which incorporated postural stability, strengthening, plyometric, and speed\\/agility drills. The outcome measures chosen to assess for interventional efficacy were: 1 Cumberland Ankle Instability Tool (CAIT) scores, 2 Star Excursion Balance Test (SEBT) reach distances, 3 ankle joint plantar flexion during drop landing and drop vertical jumping, and 4 ground reaction forces (GRFs) during walking. Results CAIT and SEBT scores improved following participation in the programme. The angle of ankle joint plantar flexion decreased at the point of initial contact during the drop landing and drop vertical jumping tasks, indicating that the ankle joint was in a less vulnerable position upon landing following participation in the programme. Furthermore, GRFs were reduced whilst walking post-intervention. Conclusions The 6-week dynamic neuromuscular training programme improved parameters of ankle joint sensorimotor control in an athlete with CAI. Further research is now required in a larger cohort of subjects to determine the effects of neuromuscular training on ankle joint injury risk factors.

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Cobbe, Sinead

2017-12-05

Complex decongestive therapy (CDT) is a regimen of physical treatment for lymphedema. Its effectiveness is unknown in advanced cancer patients. This study evaluates effectiveness of CDT in this population.

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Garvey, P

2013-01-01

Salmonella Typhimurium DT8 was a very rare cause of human illness in Ireland between 2000 and 2008, with only four human isolates from three patients being identified. Over a 19-month period between August 2009 and February 2011, 34 confirmed cases and one probable case of Salmonella Typhimurium DT8 were detected, all of which had an MLVA pattern 2-10-NA-12-212 or a closely related pattern. The epidemiological investigations strongly supported a linkbetween illness and exposure to duck eggs. Moreover, S. Typhimurium with an MLVA pattern indistinguishable (or closely related) to the isolates from human cases, was identified in 22 commercial and backyard duck flocks, twelve of which were linked with known human cases. A range of control measures were taken at farm level, and advice was provided to consumers on the hygienic handling and cooking of duck eggs. Although no definitive link was established with a concurrent duck egg-related outbreak of S. Typhimurium DT8 in the United Kingdom, it seems likely that the two events were related. It may be appropriate for other countries with a tradition of consuming duck eggs to consider the need for measures to reduce the risk of similar outbreaks.

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Corvin, Aiden P

2011-11-11

Abstract Progress is being made in schizophrenia genomics, suggesting that this complex brain disorder involves rare, moderate to high-risk mutations and the cumulative impact of small genetic effects, coupled with environmental factors. The genetic heterogeneity underlying schizophrenia and the overlap with other neurodevelopmental disorders suggest that it will not continue to be viewed as a single disease. This has radical implications for clinical practice, as diagnosis and treatment will be guided by molecular etiology rather than clinical diagnostic criteria.

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Bennett, D

2014-03-09

In 2006, the Buttimer report highlighted the paucity of demographic data on those applying for and entering postgraduate medical education and training (PGMET) in Ireland. Today, concerns that there is an "exodus" of graduates of Irish medical schools are at the forefront of national discussion, however, published data on PGMET remains inadequate.

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Flanagan, J M

2010-02-01

Classical or transferase-deficient galactosaemia is an inherited metabolic disorder caused by mutation in the human Galactose-1-phosphate uridyl transferase (GALT) gene. Of some 170 causative mutations reported, fewer than 10% are observed in more than one geographic region or ethnic group. To better understand the population history of the common GALT mutations, we have established a haplotyping system for the GALT locus incorporating eight single nucleotide polymorphisms and three short tandem repeat markers. We analysed haplotypes associated with the three most frequent GALT gene mutations, Q188R, K285N and Duarte-2 (D2), and estimated their age. Haplotype diversity, in conjunction with measures of genetic diversity and of linkage disequilibrium, indicated that Q188R and K285N are European mutations. The Q188R mutation arose in central Europe within the last 20 000 years, with its observed east-west cline of increasing relative allele frequency possibly being due to population expansion during the re-colonization of Europe by Homo sapiens in the Mesolithic age. K285N was found to be a younger mutation that originated in Eastern Europe and is probably more geographically restricted as it arose after all major European population expansions. The D2 variant was found to be an ancient mutation that originated before the expansion of Homo sapiens out of Africa.

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Meehan, Maria

2012-02-05

Abstract Background Protein tyrosine phosphatase receptor delta (PTPRD) is a member of a large family of protein tyrosine phosphatases which negatively regulate tyrosine phosphorylation. Neuroblastoma is a major childhood cancer arising from precursor cells of the sympathetic nervous system which is known to acquire deletions and alterations in the expression patterns of PTPRD, indicating a potential tumor suppressor function for this gene. The molecular mechanism, however, by which PTPRD renders a tumor suppressor effect in neuroblastoma is unknown. Results As a molecular mechanism, we demonstrate that PTPRD interacts with aurora kinase A (AURKA), an oncogenic protein that is over-expressed in multiple forms of cancer, including neuroblastoma. Ectopic up-regulation of PTPRD in neuroblastoma dephosphorylates tyrosine residues in AURKA resulting in a destabilization of this protein culminating in interfering with one of AURKA\\'s primary functions in neuroblastoma, the stabilization of MYCN protein, the gene of which is amplified in approximately 25 to 30% of high risk neuroblastoma. Conclusions PTPRD has a tumor suppressor function in neuroblastoma through AURKA dephosphorylation and destabilization and a downstream destabilization of MYCN protein, representing a novel mechanism for the function of PTPRD in neuroblastoma.

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Ajetunmobi, A

2014-12-01

The impact of central nervous system (CNS) disorders on the human population is significant, contributing almost €800 billion in annual European healthcare costs. These disorders not only have a disabling social impact but also a crippling economic drain on resources. Developing novel therapeutic strategies for these disorders requires a better understanding of events that underlie mechanisms of neural circuit physiology. Studying the relationship between genetic expression, synapse development and circuit physiology in CNS function is a challenging task, involving simultaneous analysis of multiple parameters and the convergence of several disciplines and technological approaches. However, current gold-standard techniques used to study the CNS have limitations that pose unique challenges to furthering our understanding of functional CNS development. The recent advancement in nanotechnologies for biomedical applications has seen the emergence of nanoscience as a key enabling technology for delivering a translational bridge between basic and clinical research. In particular, the development of neuroimaging and electrophysiology tools to identify the aetiology and progression of CNS disorders have led to new insights in our understanding of CNS physiology and the development of novel diagnostic modalities for therapeutic intervention. This review focuses on the latest applications of these nanotechnologies for investigating CNS function and the improved diagnosis of CNS disorders.

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McLoughlin, Kathleen

2015-11-24

For most people, home is the preferred place of care and death. Despite the development of specialist palliative care and primary care models of community based service delivery, people who are dying, and their families\\/carers, can experience isolation, feel excluded from social circles and distanced from their communities. Loneliness and social isolation can have a detrimental impact on both health and quality of life. Internationally, models of social and practical support at the end of life are gaining momentum as a result of the Compassionate Communities movement. These models have not yet been subjected to rigorous evaluation. The aims of the study described in this protocol are: (1) to evaluate the feasibility, acceptability and potential effectiveness of The Good Neighbour Partnership (GNP), a new volunteer-led model of social and practical care\\/support for community dwelling adults in Ireland who are living with advanced life-limiting illness; and (2) to pilot the method for a Phase III Randomised Controlled Trial (RCT).

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Higgs, Rowan

2010-01-01

Ro52 is a member of the TRIM family of single-protein E3 ligases and is also a target for autoantibody production in systemic lupus erythematosus and Sjögren\\'s syndrome. We previously demonstrated a novel function of Ro52 in the ubiquitination and proteasomal degradation of IRF3 following TLR3\\/4 stimulation. We now present evidence that Ro52 has a similar role in regulating the stability and activity of IRF7. Endogenous immunoprecipitation of Ro52-bound proteins revealed that IRF7 associates with Ro52, an effect which increases following TLR7 and TLR9 stimulation, suggesting that Ro52 interacts with IRF7 post-pathogen recognition. Furthermore, we show that Ro52 ubiquitinates IRF7 in a dose-dependent manner, resulting in a decrease in total IRF7 expression and a subsequent decrease in IFN-alpha production. IRF7 stability was increased in bone marrow-derived macrophages from Ro52-deficient mice stimulated with imiquimod or CpG-B, consistent with a role for Ro52 in the negative regulation of IRF7 signalling. Taken together, these results suggest that Ro52-mediated ubiquitination promotes the degradation of IRF7 following TLR7 and TLR9 stimulation. As Ro52 is known to be IFN-inducible, this system constitutes a negative-feedback loop that acts to protect the host from the prolonged activation of the immune response.

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Deane, Richard P

2015-10-09

Team Objective Structured Bedside Assessment (TOSBA) is a learning approach in which a team of medical students undertake a set of structured clinical tasks with real patients in order to reach a diagnosis and formulate a management plan and receive immediate feedback on their performance from a facilitator. TOSBA was introduced as formative assessment to an 8-week undergraduate teaching programme in Obstetrics and Gynaecology (O&G) in 2013\\/14. Each student completed 5 TOSBA sessions during the rotation. The aim of the study was to evaluate TOSBA as a teaching method to provide formative assessment for medical students during their clinical rotation. The research questions were: Does TOSBA improve clinical, communication and\\/or reasoning skills? Does TOSBA provide quality feedback?

The role of incentive design in parliamentarian anti-corruption programmes / Bryane Michael, Aare Kasemets

Index Scriptorium Estoniae

Michael, Bryane

2007-01-01

Motivatsioonidest ja viisidest, kuidas korruptsioonivastased programmid parlamendis aitavad parlamendiliikmetel koguda poliitilist kapitali valijate nõudmiste, poliitilise võitluse, eestkoste jne. haldamisel. Lisatud graafikud, tabelid ja diagramm

Grounded Imagination: Dialogue in Context

DEFF Research Database (Denmark)

Eriksen, Mette Agger; Buscher, Monika; Christensen, Michael

Monika Buscher is an ethnomethodologist at the sociology department at Lancaster University, UK. Her research interests include video ethnography, epistemic sociology, interdisciplinary theory and practice for system design, science and technology studies. With architect Mette Agger Eriksen and s...... and senior software designer Michael Christensen, she will describe the working methodology of their interdisciplinary design team that ‘designs by working with, rather than against the fact that technologies are malleable and transformative cultural objects’....

CITRA PERUSAHAAN DALAM BERITA KRISIS PERUSAHAAN: Konstruksi Citra Perusahaan Daerah Taman Satwa (PDTS Kebun Binatang Surabaya dalam Teks Berita Kematian Michael di Harian Jawa Pos dan Sindo

Directory of Open Access Journals (Sweden)

Theresia Intan Putri Hartiana

2014-12-01

Full Text Available Penelitian ini dilakukan untuk melihat bagaimana Harian Jawa Pos dan Sindo membentuk citra Perusahaan Daerah Taman Satwa (PDTS Kebun Binatang Surabaya (KBS dikonstruksikan dalam berita krisis kematian Michael. Metode yang digunakan dalam penelitian ini adalah framing Entman dengan merujuk pada pemberian definisi, penelasan, evaluasi, dan rekomendasi acana untuk melihat penekanan pada kerangka berpikir terhadap peristiwa yang dicanangkan. Citra PDTS KBS dalam Harian Jawa Pos memperlihatkan adanya kondisi Kebun Binatang Surabaya sudah tidak layak bagi satwanya dan kesengajaan keterlibatan orang dalam menjadi penyebab kematian Singa KBS mati tergantung. Citra PDTS KBS oleh Koran Sindo ditampilkan sebagai pihak yang harus bertanggungjawab atas kelalaian dan kecerobohannya dalam memelihara satwa sehingga mengakibatkan terjadi kematian satwa yang tidak wajar. Hal tersebut terlihat dari analisis makrostruktur teks yang memaparkan bahwa kepolisian dilibatkan untuk menyelidiki singa yang mati tergantung akibat kelalaian PDTS KBS dalam pengelolaan satwa. Pemberitaan yang dimunculkan oleh media massa patut menjadi perhatian oleh praktisi Public Relations. Berita yang dikonstruksi negatif secara terus menerus dapat memberikan pengaruh negatif pula di dalam benak pembaca. Beberapa pernyataan negatif yang muncul dalam teks pemberitaan dapat dijadikan sebagai dasar perencanaan bagi humas PDTS KBS dalam penanganan krisis dan perbaikan citra setelah krisis.

Design of Experiments for Model Calibration of Multi-Physics Systems with Targeted Events of Interest

Science.gov (United States)

2017-03-01

STATEMENT. *//Signature// //Signature// BENJAMIN P. SMARSLOK MICHAEL S. BROWN, Branch Chief Program Manager Hypersonic Sciences...CONTRACT NUMBER In-house 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) Benjamin P. Smarslok (AFRL/RQHF) Diane Villanueva...a flowchart of the process used to find the optimal geometry and instrumentation. In this study, the stopping criterion is the number of tests that

'Irish & Roman Catholic Which Upsets All the People Here': Michael McDonnell and British Colonial Justice in Mandatory Palestine, 1927-1936.

Science.gov (United States)

Davis, Simon

2017-10-23

In 1927 Michael McDonnell, a diasporic Irish Catholic, was appointed Mandatory Palestine's Chief Justice, being directed to institute firm British-style legal-judicial foundations for future self-governance. This entailed common, equal status for Arab and Jewish Palestinians, implicitly de-privileging the Jewish National Home. McDonnell was resisted in this by the British Mandate's Anglo-Jewish, pro-Zionist Attorney General, Norman Bentwich. McDonnell prevailed but only at the cost of being characterized lastingly as a pro-Arab, Catholic anti-Semite. McDonnell's continuing defence of a supreme, independent judiciary antagonized the Palestine Executive of High Commissioner Arthur Wauchope, who tried to co-opt rather than subordinate Zionist interests. Consequent frictions culminated in 1936 with McDonnell adjudicating against supra-legal British repression of Palestine's great Arab rebellion. For this he was dismissed and ostracized, subsequently publishing critiques of British policy in fringe right-wing organs. Yet McDonnell professed explicitly non-racist views, reflecting a liberal-minded, constitutional Irish nationalist equation of Palestine with Ireland, seeing comparable settler-colonial abuses and native distress as remediable only by transcendentally impartial justice. Britain reneging on these principles led McDonnell, like those Irish imperial servants noted in India, to identify with colonial subjects against colonialism. His case is one of empire as a system of domination being challenged from within, although his removal foreshadowed emerging imperial counter-insurgency's tendency not only to repress subject populations but deny civil-progressive alternatives for managing post-colonial transition. © The Author [2017]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

75 FR 72807 - Taking of Marine Mammals Incidental to Specified Activities; U.S. Marine Corps Training Exercises...

Science.gov (United States)

2010-11-26

... the application are available by writing to Michael Payne, Chief, Permits, Conservation and Education...) warfare training, including bombing, strafing, special (laser systems) weapons; surface fires using non... Guidelines designed to prevent harassment to marine mammals ( http://www.nmfs.noaa.gov/pr/education/southeast...

77 FR 40857 - Large Power Transformers From the Republic of Korea: Final Determination of Sales at Less Than...

Science.gov (United States)

2012-07-11

... verification procedures, including examination of relevant accounting and production records, as well as... product definition encompasses all such LPTs regardless of name designation, including but not limited to... Neal M. Halper, Director, Office of Accounting, through Michael P. Martin, Lead Accountant, entitled...

Synthesis of a stationary phase based on silica modified with branched octadecyl groups by Michael addition and photoinduced thiol-yne click chemistry for the separation of basic compounds.

Science.gov (United States)

Huang, Guang; Ou, Junjie; Wang, Hongwei; Ji, Yongsheng; Wan, Hao; Zhang, Zhang; Peng, Xiaojun; Zou, Hanfa

2016-04-01

A novel silica-based stationary phase with branched octadecyl groups was prepared by the sequential employment of the Michael addition reaction and photoinduced thiol-yne click chemistry with 3-aminopropyl-functionalized silica microspheres as the initial material. The resulting stationary phase denoted as SiO2 -N(C18)4 was characterized by elemental analysis, FTIR spectroscopy and Raman spectroscopy, demonstrating the existence of branched octadecyl groups in silica microspheres. The separations of benzene homologous compounds, acid compounds and amine analogues were conducted, demonstrating mixed-mode separation mechanism on SiO2 -N(C18)4 . Baseline separation of basic drugs mixture was acquired with the mobile phase of acetonitrile/H2 O (5%, v/v). SiO2 -N(C18)4 was further applied to separate Corydalis yanhusuo Wang water extracts, and more baseline separation peaks were obtained for SiO2 -N(C18)4 than those on Atlantis dC18 column. It can be expected that this new silica-based stationary phase will exhibit great potential in the analysis of basic compounds. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Perspectives in the effective use of fluoride in Asia

DEFF Research Database (Denmark)

Petersen, P E; Phantumvanit, P

2012-01-01

Dental caries is the most prevalent chronic disease affecting human populations worldwide. The diverse disease patterns across and within countries are related to socio-behavioral determinants, demographic factors, environmental conditions, and the availability and accessibility of oral health...... services, in particular, exposure to disease prevention programs (Petersen, 2003, 2008a). Benefits of fluoride for caries prevention have been substantiated in many countries (Petersen and Lennon, 2004; Jones et al., 2005). In the second half of the 20th century, this focus shifted to the development...... al., 2003; Australian Government, 2007). The Asian workshop held in Phan-Nga, Thailand, during March 22-24, 2011, aimed to discuss current information on fluoride and dental caries, as well as to try identifying barriers and opportunities that countries of Asia may have for implementing such programs...

Browse Title Index

African Journals Online (AJOL)

Vol 25 (2015), Preparing an Online Dictionary of Business Communication: From Idea to Design, Abstract PDF. Sven Tarp. Vol 7 (1997), Probleme der textauswahl für einen elektronischen thesaurus: tagungsbericht, Abstract PDF. Michael Schlaefer. Vol 26 (2016), Probleme in Bezug auf die slowenische lexikographische ...

Computer Contribution Act of 1983. Hearing before the Subcommittee on Select Revenue Measures of the Committee on Ways and Means. House of Representatives, Ninety-Eighth Congress, First Session, on H.R.701 (San Francisco, California).

Science.gov (United States)

Congress of the U.S., Washington, DC. House Committee on Ways and Means.

This hearing on legislation designed to encourage contributions of computers and computer equipment to elementary and secondary schools emphasizes California's experience with a state-level program. Testimony is included from the following witnesses: Kay Pacheco, Alameda County Office of Education; Michael D. Rashkin, Apple Computer, Inc.; Barbara…

77 FR 67020 - Performance Review Board Appointments

Science.gov (United States)

2012-11-08

..., Tommy Beck, Richard Belin, Alletta Berrigan, Michael Black, Michael Black, Steven Blanchard, Mary Josie..., Robert Reidenbach, Dennis Reynolds, Michael Rice, Bryan Roberson, Edwin Rountree, Carl Russ, David...

Fulltext PDF

Indian Academy of Sciences (India)

Physics. “for theoretical discoveries of topological phase transitions and topological phases of matter” to. David J Thouless, University of Washington, Seattle, WA, USA. F Duncan M Haldane, Princeton University, Princeton, NJ, USA. J Michael Kosterlitz, Brown University, Providence, RI, USA. Chemistry. “for the design and ...

Notes on Michael Schülke's pselaphine collections from China. - Tyrini. I. genera Labomimus Sharp, Linan Hlaváč and Pselaphodes Westwood (Coleoptera, Staphylinidae, Pselaphinae).

Science.gov (United States)

Yin, Zi-Wei; Li, Li-Zhen

2012-01-01

This paper is the first of a series that deals with Dr. Michael Schülke's collection of Pselaphinae from China. The tyrine genera Labomimus Sharp, Linan Hlaváč and Pselaphodes Westwood are chosen for the first part. The study revealed fourteen new species, all described and illustrated: Labomimus cognatus Yin & Li, sp. n. (Yunnan), Labomimus dabashanus Yin & Li, sp. n. (Hubei, Shaanxi), Labomimus mirus Yin & Li, sp. n. (Yunnan), Labomimus paratorus Yin & Li, sp. n. (Shaanxi), Labomimus sarculus Yin & Li, sp. n. (Yunnan), Labomimus schuelkei Yin & Li, sp. n. (Shaanxi), Labomimus vespertilio Yin & Li, sp. n. (Yunnan), Linan tendothorax Yin & Li, sp. n. (Yunnan), Pselaphodes distincticornis Yin & Li, sp. n. (Yunnan), Pselaphodes erlangshanus Yin & Li, sp. n. (Sichuan), Pselaphodes flexus Yin & Li, sp. n. (Yunnan), Pselaphodes tibialis Yin & Li, sp. n. (Yunnan), Pselaphodes venustus Yin & Li, sp. n. (Yunnan) and Pselaphodes zhongdianus Yin & Li, sp. n. (Yunnan). Pselaphodes jizushanus Yin, Li & Zhao is recorded from a new locality in Yunnan and its aedeagus is newly illustrated; new province records for Pselaphodes nomurai Yin, Li & Zhao is provided. Labomimus torus (Yin, Li & Zhao), comb. n. is moved from Pselaphodes after an examination of the holotype. Species represented only by unassociated females are listed with label data.

Channel CAT: A Tactical Link Analysis Tool

Science.gov (United States)

1997-09-01

NAVAL POSTGRADUATE SCHOOL Monterey, California THESIS CHANNEL CAT : A TACTICAL LINK ANALYSIS TOOL by Michael Glenn Coleman September 1997 Thesis...REPORT TYPE AND DATES COVERED September 1997 Master’s Thesis 4. TITLE AND SUBTITLE CHANNEL CAT : A TACTICAL LINK ANALYSIS TOOL 5. FUNDING NUMBERS 6...tool, the Channel Capacity Analysis Tool (Channel CAT ), designed to provide an automated tool for the anlysis of design decisions in developing client

Colonial Empires of the East and the Eest: Images of the Other, from Tacito to David Malouf, from Salman Rushdie to Michael Ondaatje

Directory of Open Access Journals (Sweden)

Elvira Gòdono

2011-11-01

Full Text Available Many centuries before Joseph Conrad’s Heart of Darkness (1902 and Rudyard Kipling’s Kim (1901 were published, the East and West were still divided, as in Tacito’s De Germania, by a limes also visible in David Malouf’s An Imaginary Life (1978, in which the poet Ovid exiled at Tomi, is friends with the savage Child, of animal nature in a human body, similar to the metamorphic migrants of Salman Rushdie’s The Satanic Verses (1988, which hides the magnificent and ancient East of Mahābhārata and Rāmāyana in many Western identities, lost in diabolic European cities. This chaotic antithesis in Michael Ondaatje’s pages lets Sri Lanka’s childish ghosts float amidst stories of peregrination and in search of a Promised Land. In the Skin of a Lion (1987 includes an epigraph from the ancient poem of Gilgamesh, an Eastern echo in a novel profoundly important for many Western studies that often focus on the theory of the canon or on postmodern literature. These categories are discussed with the prospect of broadening cultural and post-colonial studies, in order to merge theory of genres and thematic criticism with anthropology, mythology, and ethnology. Multiple citations expand the original object of research, adding the colonial prophecy present in North American myths, as demonstrated by Margaret Atwood, Margaret Laurence or Lévi-Strauss. Incessantly moving from one space to another, authors give voice to the native cry from multiple perspectives, narrating – like all colonial empires founded on human cruelty– the beast’s nature that has shown its worst aspect.

De Dicto Moral Desires and the Moral Sentiments : Adam Smith on the Role of De Dicto Moral Desires in the Virtuous Agent

NARCIS (Netherlands)

Archer, Alfred

2017-01-01

What role should a motivation to do the right thing, read de dicto, play in the life of a virtuous agent? According to a prominent argument from Michael Smith, those who are only ever motivated by such a desire are moral fetishists. Smith’s argument is designed to support motivational judgment

78 FR 35340 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of a Proposed Rule Change...

Science.gov (United States)

2013-06-12

... with Inventory, 86 J. FIN. ECON. 513, 513 (2007); and Narayan Y. Naik & Pradeep K. Yadav, Trading Costs... Liquidity, Asset Prices, and Welfare, 95 J. FIN. ECON. 107, 109 (2010); Wen Mao & Michael S. Pagano..., that the rules of a national securities exchange be designed to promote just and equitable principles...

Michael's Inside Scoop: Genetics

Science.gov (United States)

... Snow, the First Epidemiologist Microbe Multiplication Magic Scientific Poster Session Poisoned Picnic The Energy Equation Flu Season- ... pieces of advice: 1. Follow the basics of good health. You know ’em. Eat healthy , Get plenty ...

INTERVIEW WITH MICHAEL WELKER

African Journals Online (AJOL)

basic level, you argued that at least two elements are necessary for an utterance to be ... Henco: In light of the question above, how would you describe what you ... books. A broad biblical orientation, the appreciation of the divine Law (with.

Linnade klubi / Michael Bloomberg

Index Scriptorium Estoniae

Bloomberg, Michael

2007-01-01

New Yorgi linnapea räägib vajadusest suurendada linnadevahelist koostööd. Sündimas on uus globaalne urbanistlik kogukond, milles linnad teevad üksteisega koostööd ühesuguste probleemide kallal, võisteldes samal ajal omavahel globaalsel turul

Michael F. Crowley | NREL

Science.gov (United States)

Pittsburgh Supercomputing Center, and at The Scripps Research Institute with David Case and Charles Brooks NIH-funded collaboration with Professor Charles L. Brooks III at the University of Michigan Areas of to determine source of twisting in hydrogen bonding patterns. This modeling will help to understand

Michael York, Pagan Theology

Directory of Open Access Journals (Sweden)

Terry GIFFORD

2004-10-01

Full Text Available For Christian missionaries the word ‘pagan’ was a pejorative that implied ‘primitive’, either in the sense of devil worship or barren atheism. From this tradition the word has been associated with either the worship of the wrong gods immanent in the natural environment, or of a godless superstition relating to the spirits alive in nature. Of course, Christianity has been adept at incorporating a diversity of pagan beliefs, occasions and rituals into its colonising practice throughout the worl...

[Michael Servetus: symphony in ].

Science.gov (United States)

Gracia Guillén, Diego

2004-01-01

On October 27th 1553, the physician and religious reformer Miguel Servet was burnt at stake. The 450th anniversary of his death took place, therefore, a few months ago. This is a fact which deserves being taken into account, not only because of the importance of the individual, but also, and mainly, because during the last years some important historiographical advances have changed the traditional approach, giving place to a new and more accurate analysis to his life and work. The topic image of Servet spread by the Spanish historiography of the 19th and most of the 20th Centuries has been that of a scientific genius, discoverer of the pulmonary circulation of blood, but also that of a crazy theologian with absurd ideas about some basic Christian dogmas, specially the Holy Trinity. This image is now considered absolutely misleading. The historiography of the complex religious movements of the 16th Century has shown that Servet, far from being a crazy theologian absolutely disconnected of the religious movements of the Century, was instead one of the leaders of an important Christian movement which G. H. Williams called He consecrated all his life to this goal, which also was the reason of his death, always showing an absolute and admirable intellectual and human coherence. To these goals he subdued any other objective, as well as the study and the exercise of medicine. This gives the basis to correctly understand the fact, never explained convincingly until now, why his great scientific discovery, the pulmonary circulation of blood, appeared as a minimal part in the heart of a theological book.

Tiheduse kurvid / Michael Sorkin

Index Scriptorium Estoniae

Sorkin, Michael

2007-01-01

Autor toob välja linnade kasvu mõju maa ökoloogiale. Tema sõnul on demokraatliku linna jaoks kriitiline tihedus linlike vormide ning käitumisviiside tihke kogum ning just tiheduses on vastus jätkusuutlikuks edasi elamiseks meie planeedil

Dignital Biological Converter

Science.gov (United States)

2014-01-03

DARPA Contracting Officer: Michael Blackstone Submitted by: HEATHER GOUVIS Synthetic Genomics, Inc. 11149 NORTH TORREY PINES RD LA JOLLA, CA...Contracting Officer Representative (COR) Email: salit@nist.gov Michael Blackstone DARPA Contracting Officer Michael.Blackstone@darpa.mil DARPA

Inserção de catalisador híbrido na síntese de beta-tiocetonas

Directory of Open Access Journals (Sweden)

Mariana Pompilio Darbem

2012-06-01

Full Text Available The Michael reaction (or Michael addition involves the addition of a nucleophile, called Michael donor, to an electrophile (α,β-unsaturated, called Michael acceptor. Literature reports several types of nucleophiles applied in this reaction. Among them we can mention compounds containing a sulfur atom. When these nucleophiles are applied to this reaction, it is called as thia-Michael reaction. In this study thiophenol, p- chlorothiophenol and p-methoxythiophenol were tested as Michael donors, and several ketones and aldehydes as Michael acceptors, in order to obtain the formation of sigma bonds carbon-sulfur. Compounds that have in their structure the C-S bond are extremely important, because they can present, for example, antibiotic action, antimicrobial analgesic, and anti-HIV. This research proposes, besides the obtainment of  many beta-thioketonic compounds, the insertion of a new catalyst in thia-Michael reactions, the bis-L-zinc prolinate. This catalyst provided the obtainment of high yield compounds. The reactions were executed using ultrasound, which caused a significant decrease in the reaction time and an increase in the results obtained when compared with data obtained previously in literature. An important fact in this study is that the catalyst used is not soluble in the reaction media and it can be reused without abrupt loss of yield.

Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A

Science.gov (United States)

Han, Yi-Xin; Jiang, Yan-Long; Li, Yong; Yu, Hai-Xin; Tong, Bing-Qi; Niu, Zhe; Zhou, Shi-Jie; Liu, Song; Lan, Yu; Chen, Jia-Hua; Yang, Zhen

2017-01-01

Complex natural products are a proven and rich source of disease-modulating drugs and of efficient tools for the study of chemical biology and drug discovery. The architectures of complex natural products are generally considered to represent significant barriers to efficient chemical synthesis. Here we describe a concise and efficient asymmetric synthesis of 19-dehydroxyl arisandilactone A--which belongs to a family of architecturally unique, highly oxygenated nortriterpenoids isolated from the medicinal plant Schisandra arisanensis. This synthesis takes place by means of a homo-Michael reaction, a tandem retro-Michael/Michael reaction, and Cu-catalysed intramolecular cyclopropanation as key steps. The proposed mechanisms for the homo-Michael and tandem retro-Michael/Michael reactions are supported by density functional theory (DFT) calculation. The developed chemistry may find application for the synthesis of its other family members of Schisandraceae nortriterpenoids.

Product modelling: '20 years of stalemate'?

DEFF Research Database (Denmark)

Galle, Per

1998-01-01

In a recent special issue of Design Studies Michael Ramscar, John Lee, and Helen Pain level a severe criticism against a field of research known as product modeling; a criticism that would be rather damaging if it were based on cogent arguments. I shall argue in this paper that it is not....

Support for Implications of Compressive Sensing Concepts to Imaging Systems

Science.gov (United States)

2015-08-02

Justin Romberg Georgia Tech jrom@ece.gatech.edu Emil Sidky University of Chicago sidky@uchicago.edu Michael Stenner MITRE mstenner@mitre.org Lei Tian...assessment of image quality. Michael Stenner Michael has broad interests in optical imaging, sensing, and communications, and is published in such

Expedient Access to an N -phenylpyrrolidin-2-yl Heterocycle via a ...

African Journals Online (AJOL)

Expedient Access to an N -phenylpyrrolidin-2-yl Heterocycle via a Base-Induced Intramolecular aza -Michael Reaction. ... in good overall yield when employing a stoichiometric amount of base to facilitate the intramolecular aza-Michael reaction. Keywords: aza Michael, intramolecular, catalysed, piperidine, pyrrolidine, base ...

Antiparallel Dynamic Covalent Chemistries.

Science.gov (United States)

Matysiak, Bartosz M; Nowak, Piotr; Cvrtila, Ivica; Pappas, Charalampos G; Liu, Bin; Komáromy, Dávid; Otto, Sijbren

2017-05-17

The ability to design reaction networks with high, but addressable complexity is a necessary prerequisite to make advanced functional chemical systems. Dynamic combinatorial chemistry has proven to be a useful tool in achieving complexity, however with some limitations in controlling it. Herein we introduce the concept of antiparallel chemistries, in which the same functional group can be channeled into one of two reversible chemistries depending on a controllable parameter. Such systems allow both for achieving complexity, by combinatorial chemistry, and addressing it, by switching from one chemistry to another by controlling an external parameter. In our design the two antiparallel chemistries are thiol-disulfide exchange and thio-Michael addition, sharing the thiol as the common building block. By means of oxidation and reduction the system can be reversibly switched from predominantly thio-Michael chemistry to predominantly disulfide chemistry, as well as to any intermediate state. Both chemistries operate in water, at room temperature, and at mildly basic pH, which makes them a suitable platform for further development of systems chemistry.

75 FR 17894 - Approval and Promulgation of Air Quality Implementation Plans; Wisconsin; Particulate Matter...

Science.gov (United States)

2010-04-08

... instructions for submitting comments. 2. E-mail: compher.michael@epa.gov . 3. Fax: (312) 692-2511. 4. Mail: Michael Compher, Acting Chief, Criteria Pollutant Section, Air Programs Branch (AR-18J), U.S. Environmental Protection Agency, 77 West Jackson Boulevard, Chicago, Illinois 60604. 5. Hand Delivery: Michael...

Design, synthesis, and evaluation of curcumin derivatives as Nrf2 activators and cytoprotectors against oxidative death.

Science.gov (United States)

Tu, Zhi-Shan; Wang, Qi; Sun, Dan-Dan; Dai, Fang; Zhou, Bo

2017-07-07

Activation of nuclear factor erythroid-2-related factor 2 (Nrf2) has been proven to be an effective means to prevent the development of cancer, and natural curcumin stands out as a potent Nrf2 activator and cancer chemopreventive agent. In this study, we synthesized a series of curcumin analogs by introducing the geminal dimethyl substituents on the active methylene group to find more potent Nrf2 activators and cytoprotectors against oxidative death. The geminally dimethylated and catechol-type curcumin analog (compound 3) was identified as a promising lead molecule in terms of its increased stability and cytoprotective activity against the tert-butyl hydroperoxide (t-BHP)-induced death of HepG2 cells. Mechanism studies indicate that its cytoprotective effects are mediated by activating the Nrf2 signaling pathway in the Michael acceptor- and catechol-dependent manners. Additionally, we verified by using copper and iron ion chelators that the two metal ion-mediated oxidations of compound 3 to its corresponding electrophilic o-quinone, contribute significantly to its Nrf2-dependent cytoprotection. This work provides an example of successfully designing natural curcumin-directed Nrf2 activators by a stability-increasing and proelectrophilic strategy. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Engineering and Physics Optimization of Breed and Burn Fast Reactor Systems. NUCLEAR ENERGY RESEARCH INITIATIVE (NERI) QUARTERLY PROGRESS REPORT

International Nuclear Information System (INIS)

Pavel Hejzlar; Peter Yarsky; Mike Driscoll; Dan Wachs; Kevan Weaver; Ken Czerwinski; Mike Pope; James Parry; Marshall, Theron D.; Davis, Cliff B.; Dustin Crawford; Thomas Hartmann; Pradip Saha

2005-01-01

This project is organized under four major tasks (each of which has two or more subtasks) with contributions among the three collaborating organizations (MIT, INEEL and ANL-West): Task A: Core Physics and Fuel Cycle; Task B: Core Thermal Hydraulics; Task C: Plant Design; Task D: Fuel Design The lead PI, Michael J. Driscoll, has consolidated and summarized the technical progress submissions provided by the contributing investigators from all sites, under the above principal task headings

Engineering and Physics Optimization of Breed and Burn Fast Reactor Systems; NUCLEAR ENERGY RESEARCH INITIATIVE (NERI) QUARTERLY PROGRESS REPORT

Energy Technology Data Exchange (ETDEWEB)

ERROR, [value too long for type character varying(50); Hejzlar, Pavel; Yarsky, Peter; Driscoll, Mike; Wachs, Dan; Weaver, Kevan; Czerwinski, Ken; Pope, Mike; Parry, James; Marshall, Theron D.; Davis, Cliff B.; Crawford, Dustin; Hartmann, Thomas; Saha, Pradip

2005-01-31

This project is organized under four major tasks (each of which has two or more subtasks) with contributions among the three collaborating organizations (MIT, INEEL and ANL-West): Task A: Core Physics and Fuel Cycle; Task B: Core Thermal Hydraulics; Task C: Plant Design; Task D: Fuel Design The lead PI, Michael J. Driscoll, has consolidated and summarized the technical progress submissions provided by the contributing investigators from all sites, under the above principal task headings.

Modeling Non-Linear Material Properties in Composite Materials

Science.gov (United States)

2016-06-28

Technical Report ARWSB-TR-16013 MODELING NON-LINEAR MATERIAL PROPERTIES IN COMPOSITE MATERIALS Michael F. Macri Andrew G...REPORT TYPE Technical 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE MODELING NON-LINEAR MATERIAL PROPERTIES IN COMPOSITE MATERIALS ...systems are increasingly incorporating composite materials into their design. Many of these systems subject the composites to environmental conditions

"Ruumi" elutubade top

Index Scriptorium Estoniae

2007-01-01

Andekamaid leiutisi ja ilusaimaid asju maailma arhitektidelt ja disaineritelt - Barbara Dujardini ja Michael Hofmani sissetõmmatav rõdu, disainiklassiku Finn Juhli romantiline sohva "Poet", John Braueri läbipaistev laudlina imiteeriv lauake, Gala Writhi õhus hõljuv lamamistool, Kalle-Priit Pruudeni diivanid ja lillemustriline tool "Luisa" disainistuudiolt GAMplusFRATESI ning kell disainirühmituselt Thwart Design

Narrative House: A Metaphor For Narrative Therapy: Tribute To ...

African Journals Online (AJOL)

This article is a tribute to Michael White, co-founder of narrative therapy, who passed away on 5 April 2008. Michael White and David Epston founded a substantial and ground-breaking psychological movement based on narrative therapy. Michael touched with dignity and changed for the better the lives of thousands.

Notes on the notion of "just war"

DEFF Research Database (Denmark)

Zangenberg, Mikkel

2009-01-01

En Bordieu-inspireret analyse af ideen om "retfærdig krig", og forholdet mellem intellektuelle og krigsførsel - set i lyset af kritiske interventioner i forhold til Irak-krigen ved Michael Walzer, Slavoj Zizek, og Antonio Negri og Michael Hardt. Udgivelsesdato: july 09......En Bordieu-inspireret analyse af ideen om "retfærdig krig", og forholdet mellem intellektuelle og krigsførsel - set i lyset af kritiske interventioner i forhold til Irak-krigen ved Michael Walzer, Slavoj Zizek, og Antonio Negri og Michael Hardt. Udgivelsesdato: july 09...

Just War? Iraq in the Bonfire between Walzer, Zizek, Hardt and Negri

DEFF Research Database (Denmark)

Zangenberg, Mikkel

2008-01-01

Artiklen undersøger det generelle spørgsmål om retfærdig krig, og om relationen mellem intellektuelle og krig, ved at inspicere henholdsvis Michael Walzer, Slavoj Zizek, Michael Hardt og Antonio Negris manøvrer overfor USA's krig i Irak.......Artiklen undersøger det generelle spørgsmål om retfærdig krig, og om relationen mellem intellektuelle og krig, ved at inspicere henholdsvis Michael Walzer, Slavoj Zizek, Michael Hardt og Antonio Negris manøvrer overfor USA's krig i Irak....

Learning Is the Journey: From Process Reengineering to Systemic Customer-Service Design at the United States Department of Veterans Affairs, Veterans Benefits Administration

Science.gov (United States)

2013-05-23

5 Michael Beer , Russell A Eisenstat, and Bert Spector, “Why Change Programs Don’t Produce Change,” On Change Management (Boston: Harvard Business...mechanism, thermodynamics , cybernetics, and finally, chaoplexity (see Table 2 below). While Bousquet uses the construct of warfare to trace his...tackle the backlog continue to bring the solution into the realm of thermodynamics or mechanism. For example, the strides made by lean six sigma

Building Reproducible Science with Singularity Containers

CERN Multimedia

CERN. Geneva

2018-01-01

Michael Bauer first began working with containers at GSI national lab in Darmstadt, Germany, in 2017 while taking a semester off of school at the University of Michigan. Michael met Greg Kurtzer, project lead of Singularity, during his time at GSI and he began contributing heavily to the Singularity project. At the start of summer 2017, Greg hired Michael to work at the ...

John Lennon, autograph hound: The fan-musician community in Hamburg's early rock-and-roll scene, 1960–65

Directory of Open Access Journals (Sweden)

Julia Sneeringer

2011-03-01

Full Text Available This article explores the Beat music scene in Hamburg, West Germany, in the early 1960s. This scene became famous for its role in incubating the Beatles, who played over 250 nights there in 1960–62, but this article focuses on the prominent role of fans in this scene. Here fans were welcomed by bands and club owners as cocreators of a scene that offered respite from the prevailing conformism of West Germany during the Economic Miracle. This scene, born at the confluence of commercial and subcultural impulses, was also instrumental in transforming rock and roll from a working-class niche product to a cross-class lingua franca for youth. It was also a key element in West Germany's broader processes of democratization during the 1960s, opening up social space in which the meanings of authority, respectability, and democracy itself could be questioned and reworked.

Michael Jackson: O artista perfeito

OpenAIRE

Abreu, Teresa

2011-01-01

No decorrer desta tese, abordam-se conhecimentos psicanalíticos aplicados à arte e aos artistas, mais especialmente em relação à área da música, mas que obviamente poderão ser estendidos a outras áreas artísticas. São expostas várias teorias psicanalíticas, oriundas de vários autores de renome e que nos ajudarão a compreender qual a função da arte e quais as qualidades ou características intrínsecas a um artista. Os termos arte e artista são abordados de forma exigente e em est...

The correspondance of Michael Faraday

CERN Document Server

1991-01-01

The initial volume of the correspondence of Micahel Faraday (1791-1867), published in the year of the bicentenary of his birth, covers his early years up to his discovery of electromagnetic induction in 1831. Other scientific and technical topics covered include Faraday's discovery of electromagnetic rotations (in 1821), the liquefaction of gases (in 1823) and the long series of experiments in the latter part of the 1820s to improve optical glass.

The Napoleon Graves / Michael Tarm

Index Scriptorium Estoniae

Tarm, Michael

2002-01-01

Vilniuse lähedal leiti 1812. a. Isamaasõjas hukkunud prantsuse sõdurite matmispaik. Säilmete antropoloogilised uuringud võimaldavad kindlaks määrata hukkunute vanuse, soo ja tõenäolise surma põhjuse

Tshelovek s britvoi / Michael Mayer

Index Scriptorium Estoniae

Mayer, Michael

2006-01-01

Venemaa president Vladimir Putini käitumist võib hinnata mitmeti, kriitikud süüdistavad teda demokraatia lämmatamises ning püüdes taastada nõukogude impeeriumi, kuid nad hindavad tema saavutusi. Hinnangud ja järeldused seoses Ukraina-Vene gaasitüliga, Kremli administratsiooni võim

Notes of Karol Górski in archival collections of the Archive of the General Congregation of Saint Michael the Archangel in Marki regarding Blessed Bronisław Markiewicz and his pupils

Directory of Open Access Journals (Sweden)

Roman Majka CSMA

2012-12-01

Full Text Available Professor Karol Górski (1903-1988 was an expert on spirituality in Poland, and an author of many publications, such as An outline of the history of spirituality in Poland published in Krakow in 1986. Professor was inspired by the Michaelite spirituality, while exploring the life and work of the founder of Michaelite Fathers - Blessed Father Bronislaw Markiewicz (1842-1912. Presently, Father Markiewicz's selected academic works and research material are preserved in Archive of the General Congregation of St. Michael the Archangel in Marki near Warsaw. Among many Górski's publications is an article The inner life of fr. Bronisław Markiewicz published in the journal "Our Past", Vol. 23, 1966, p. 239-278. Remaining in the collection are notes handwritten by Górski kept as "Calendarium", which attest to his thoroughness and diligence in research. Collected materials carefully prepared with the aim to enable most accurate reconstruction of the events of the Education Service of Miejsce Piastowe describe the life and work of the Blessed Markiewicz and his first pupils. Sustained contact of Górski with Michaelite Fathers is confirmed in preserved correspondence, especially the letters of fr. Valerian Moroz CSMA (1919-2005. Professor, drawing from the history of spirituality in Poland, read the current issues of the Church and was highly respectful of family values and providing care of poor people in need of help.

ALGUNOS ELEMENTOS DE LA CONSTRUCCIÓN DE “LO UNIVERSITORIO” POR LOS ESTUDIANTES DE LA UNIVERSIDAD DE CARTAGENA

Directory of Open Access Journals (Sweden)

Nancy Bolaño

2000-08-01

Full Text Available ¿Qué ocurre, cómo se amarran y desamarran los múltiples hilos que constituyen ese nudo y al tiempo nudoso conflicto de sentidos‘, ese cruce de memorias y proyectos, de representaciones y prácticas, de normativas y decisiones, en interminado desenvolvimiento en el espacio-tiempo del ámbito universitario, que es el cotidiano estudiantil de nuestra Universidad? Usualmente presurosos, colgados de las manecillas del reloj o empujados por las previsiones de la rutina, circulamos por allí profesores, directivos, administradores del alma mater, a través de este atiborrado, fluctuante, magmático teatro de acontecimientos, rumbo al escritorio doctoral, al salón de juntas a la grave reflexión, al dogma palabrero o a la invención innocua, permitiendo que, como lo cantara John Lennon, la vida sea lo que está ocurriendo mientras nosotros estamos ocupados en otras cosas.

The body as the subject’s heterotopia

Directory of Open Access Journals (Sweden)

Cleudemar Alves Fernandes

2016-10-01

Full Text Available http://dx.doi.org/10.5007/1984-8420.2016v17n2p6 This study is embodied as an enunciation space, which reflects the subject’s position, through discourses materialized in it; thus, the body is considered as a support of a social-historical objectified subject. For this proposition, we are anchored in Michel Foucault’s thought, specifically in the notions of space, heterotopias, utopia, subjectivity; and we analyze a video presented in the talent show contest Se ela dança, eu danço, from the Sistema Brasileiro de Televisão – SBT, in January, 2011. In this video, the choreog­raphy proposed by the contester John Lennon da Silva results from a rereading of the classic ballet The Dying Swan. We focus on the transformation of the subjects’ position that composes the jury and on the objectification of the dancer subject before, during and after the choreography.

A case of seropositive Neuromyelitis Optica in a paediatric patient with co-existing acute nephrotic syndrome.

Science.gov (United States)

Volkman, Thomas; Hemingway, Cheryl

2017-11-01

Neuromyelitis optica (NMO) and NMO spectrum disorder (NMOSD) is a rare relapsing autoimmune disease of the central nervous system constituting less than 1% of demyelinating diseases (Jeffery and Buncic, 1996). It preferentially affects the optic nerves and spinal cord, with the brain parenchyma generally spared. Demyelinating lesions are characterised by longitudinally extensive transverse myelitis (LETM) and often longitudinally extensive optic neuritis. Following the discovery of a novel pathogenic antibody, Aquaporin 4 in 2004 (Lennon et al., 2004) this disease has been seen as a separate entity from Multiple Sclerosis (MS). We report the case of a severe AQP4 IgG case of NMO in a 10 year old child. This case unusually had a coexisting diagnosis of acute nephrotic syndrome which has only been reported once previously in the literature 2 . This article will examine some of the treatment challenges and the spectrum of co-existing autoimmune disease in NMOSD. Copyright © 2017. Published by Elsevier B.V.

Strateegiaguru Porter, klastriguru Porter, sponsorlusguru Porter. Peaaegu, et gurude guru!

Index Scriptorium Estoniae

2005-01-01

Maailma juhtiva strateegiaguru, Harvard Business Schooli professori Michael Porteri seisukohtadest ja ideedest ettevõtete heategevuse, Interneti kui majandusharu ning klastrite kohta. Lisa: Michael Porter

Were Increased Closed Seclusions the Result of a Reinforcer-Abolishing Effect?

OpenAIRE

Poling, Alan

2013-01-01

In recent years, the motivating operation (MO) concept and the terms associated with it, including “reinforcer-abolishing effect” (Laraway, Snycerski, Michael, & Poling, 2003), have been widely used in the behavior-analytic literature (Laraway, Snycerski, Olson, Becker, & Poling, in press) and elsewhere (Lotfizadeh, Edwards, & Poling, 2013). MOs are changes in the environment that alter the reinforcing effectiveness of designated classes of stimuli, such as food or water.

Were Increased Closed Seclusions the Result of a Reinforcer-Abolishing Effect?

Science.gov (United States)

Poling, Alan

2013-01-01

In recent years, the motivating operation (MO) concept and the terms associated with it, including "reinforcer-abolishing effect" (Laraway, Snycerski, Michael, & Poling, 2003), have been widely used in the behavior-analytic literature (Laraway, Snycerski, Olson, Becker, & Poling, in press) and elsewhere (Lotfizadeh, Edwards, & Poling, 2013). MOs are changes in the environment that alter the reinforcing effectiveness of designated classes of stimuli, such as food or water.

Computing handbook computer science and software engineering

CERN Document Server

Gonzalez, Teofilo; Tucker, Allen

2014-01-01

Overview of Computer Science Structure and Organization of Computing Peter J. DenningComputational Thinking Valerie BarrAlgorithms and Complexity Data Structures Mark WeissBasic Techniques for Design and Analysis of Algorithms Edward ReingoldGraph and Network Algorithms Samir Khuller and Balaji RaghavachariComputational Geometry Marc van KreveldComplexity Theory Eric Allender, Michael Loui, and Kenneth ReganFormal Models and Computability Tao Jiang, Ming Li, and Bala

Joint Force Quarterly. Number 9, Autumn 1995

Science.gov (United States)

1995-11-01

Peters, Jr. Production Coordinator Calvin B. Kelley Senior Copy Editor Justin Burkhart Editorial Intern (Summer 1995) The Typography and Design ...J. Rokke ■ C O N T E N T S 2 JFQ / Autumn 1995 ■ O U T O F J O I N T 24 Jointness by Design , Not Accident by Michael C. Vitale ■ J F Q F O R U M...take power, or Iran and Iraq have a free hand, U.S. interests would suffer a serious setback. These factors have altered the region’s geo- graphic

75 FR 26225 - Adequacy Status of the Chicago, Illinois Area Submitted 8-Hour Ozone Redesignation and...

Science.gov (United States)

2010-05-11

... Agency, Region 5, 77 West Jackson Boulevard, Chicago, Illinois 60604 (312) 353-6680, leslie.michael@epa..., 2010. FOR FURTHER INFORMATION CONTACT: Michael Leslie, Environmental Engineer, Criteria Pollutant...

75 FR 24944 - Adequacy Status of the Milwaukee-Racine, Door County, Manitowoc County, and Sheboygan County...

Science.gov (United States)

2010-05-06

... 5, 77 West Jackson Boulevard, Chicago, Illinois 60604, (312) 353-6680, leslie.michael@epa.gov... FURTHER INFORMATION CONTACT: Michael Leslie, Environmental Engineer, Criteria Pollutant Section (AR-18J...

Design of multimodal degradable hydrogels for controlled therapeutic delivery

Science.gov (United States)

Kharkar, Prathamesh Madhav

Hydrogels are of growing interest for the delivery of therapeutics to specific sites in the body. For localized drug delivery, hydrophilic polymeric precursors often are laden with bioactive moieties and then directly injected to the site of interest for in situ gel formation. The release of physically entrapped cargo is dictated by Fickian diffusion, degradation of the drug carrier, or a combination of both. The goal of this work was to design and characterize degradable hydrogel formulations that are responsive to multiple biologically relevant stimuli for degradation-mediated delivery of cargo molecules such as therapeutic proteins, growth factors, and immunomodulatory agents. We began by demonstrating the use of cleavable click linkages formed by Michael-type addition reactions in conjunction with hydrolytically cleavable functionalities for the degradation of injectable hydrogels by endogenous stimuli for controlled protein release. Specifically, the reaction between maleimides and thiols was utilized for hydrogel formation, where thiol selection dictates the degradability of the resulting linkage under thiol-rich reducing conditions. Relevant microenvironments where degradation would occur in vivo include those rich in glutathione (GSH), a tripeptide that is found at elevated concentrations in carcinoma tissues. Degradation of the hydrogels was monitored with rheometry and volumetric swelling measurements. Arylthiol-based thioether succinimide linkages underwent degradation via click cleavage and thiol exchange reaction in the presence of GSH and via ester hydrolysis, whereas alkylthiol-based thioether succinimide linkages only undergo degradation by only ester hydrolysis. The resulting control over the degradation rate within a reducing microenvironment resulted in 2.5 fold differences in the release profile of the model protein, a fluorescently-labeled bovine serum albumin, from dually degradable hydrogels compared to non-degradable hydrogels, where the

A Multi-Modality Mobility Concept for a Small Package Delivery UAV

Science.gov (United States)

Young, L. A.

2017-01-01

This paper will discuss a different approach to the typical notional small package delivery drone concept. Most delivery drone concepts employ a point-to-point aerial delivery CONOPS (Concept of Operations) from a warehouse directly to the front or back yards of a customers residence or a commercial office space. Instead, the proposed approach is somewhat analogous to current postal deliveries: a small aerial vehicle flies from a warehouse to designated neighborhood VTOL (Vertical Take-Off and Landing) landing spots where the aerial vehicle then converts to a "roadable" (ground-mobility) vehicle that then transits on sidewalks and/or bicycle paths till it arrives to the residence/office drop-off points. This concept and associated platform or vehicle will be referred in this paper as MICHAEL (Multimodal Intra-City Hauling and Aerial-Effected Logistics) concept. It is suggested that the MICHAEL concept potentially results in a more community friendly "delivery drone" approach.

Lunar Wormbot: Design and Development of a Ground Base Robotic Tunneling Worm for Operation in Harsh Environments

Science.gov (United States)

Boyles, Charles; Eledui, Emory; Gasser, Ben; Johnson, Josh; Long, Jay " Ben" Toy, Nathan; Murphy, Gloria

2011-01-01

From 1969 to 1972, the National Aeronautics and Space Administration (NASA) sent Apollo missions to the moon to conduct various exploration experiment. A few of the missions were directed to the study and sampling of moon soil, otherwise known as lunar regolith. The extent of the sample acquisition was limited due to the astronauts' limited ability to penetrate the moon's surface to a depth greater than three meters. However. the samples obtained were sufficient enough to provide key information pertaining to lunar regolith material properties that would further assist in future exploration endeavors. Analysis of the collected samples showed that the properties of lunar regolith may lead to knowledge of processed materials that will be beneficial for future human exploration or colonization. However, almost 40 years after the last Apollo mission, limited infonnation is known about regions underneath the moon's surface. Future lunar missions will require hardware that possesses the ability to burrow to greater depths in order to collect samples for subsequent analysis. During the summer of 2010, a team (Dr. Jessica Gaskin, Michael Kuhlman. Blaze Sanders, and Lafe Zabowski) from the NASA Robotics Academy at Marshall Space Flight Center (MSFC) was given the task of designing a robot to function as a soil collection and analysis device. Working with the National Space Science and Technology Center (NSSTC), the team was able to propose an initial design, build a prototype, and test the various subsystems of the prototype to be known as the "Lunar Wormbot" (LW). The NASA/NSSTC team then transferred the project to a University of Alabama in Huntsville (UAH) Mechanical and Aerospace Engineering (MAE) senior design class for further development. The UAH team was to utilize the NASA Systems Engineering Engine Design Process in the continuance of the Lunar Wormbot project. This process was implemented in order to coordinate the efforts of the team and guide the design of the

Crockett ja Tubbs jõuavad Eesti kinodesse / Riho Laurisaar

Index Scriptorium Estoniae

Laurisaar, Riho

2006-01-01

Ülipopulaarne teleseriaal "Miami Vice" (1984-1989) tuleb Michael Manni lavastuses suurele ekraanile, peaosades Colin Farrell ja Jamie Foxx. Meenutatakse seriaali ja selle peaosalisi Don Johnsonit ja Philip Michael Thomast

Realistic Modeling of Wireless Network Environments

Science.gov (United States)

2015-03-01

Simulation, Emulation 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON MICHAEL T...spectrum access. The detailed design and the layout of the SCM and DSP boards was outsourced to outside companies ( DRG Engineering and AmeriCAD...each position. The accuracy of the classification is limited by image quality and the algorithms. However, this general approach has proven to be

Demonstrating the Environmental & Economic Cost-Benefits of Reusing DoD’s Pre-World War II Buildings

Science.gov (United States)

2013-04-01

Cultural Resources Manager, CIV USA IMCOM, Mr. Hugo A. Gardea, CIV USA IMCOM, Mr. Michael C. Johnson, Historic Architect, and Mr. Douglas J. Yost...intended to consider the original structural design, the condition of materials, the effects of age and past usage, hurricane and other damage, and the...past usage, hurricane and other damage, and the requirements for continued service. In assessing older existing structures, the Study Team’s

An Autonomous Indicator-based pH Sensor for Oceanographic Research and Monitoring

Science.gov (United States)

2010-01-01

E-mail: michael.degrandpre@umontana.edu Co-PI: Jim Beck , MSME Sunburst Sensors, LLC, 1121 E. Broadway, Suite 114, Missoula, MT 59802 Phone...NOPP Award Number: ONR- BAA -07-040 NSF Award Number: OCE-0836807 LONG-TERM GOALS This project, funded under NOPP Topic 3A Sensors for...Spaulding continued work on establishing long- term stability of mCP. Jim Beck coordinated improvements to the design of the software and hardware

Cine club

CERN Multimedia

Cine club

2017-01-01

Wednesday 18 January 2017 at 20:00 CERN Council Chamber 35 Up Directed by Michael Apted UK, 1991, 123 minutes Director Michael Apted revisits the same group of British-born adults after a seven-year wait. The subjects are interviewed as to the changes that have occurred in their lives during the last seven years. Original version English; French subtitles Wednesday 25 January 2017 at 20:00 CERN Council Chamber 56 Up Directed by Michael Apted, Paul Almond UK, 2012, 144 minutes Director Michael Apted revisits the same group of British-born adults after a seven-year wait. The subjects are interviewed as to the changes that have occurred in their lives during the last seven years. Original version English; French subtitles Save

Cílový spotřebitel rybí restaurace

OpenAIRE

Mikšovská, Lucie

2010-01-01

The thesis is about market segmentation for the new type of the fastfood restaurant MICHAEL'S. The first part is introducing restaurant MICHAEL'S, its history and is introducing the business plan. The second part of thesis is focused on the theoretically process of segmentation which is needed for concrete segmentation of the fish fastfood. The rest of the thesis is dedicated to the theoretical project about market research which should help to find the best segments for the MICHAEL'S. Choosi...

77 FR 20820 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

Science.gov (United States)

2012-04-06

... Trust, and Gloria Foley, all of Lovington, Illinois, and Paul Michael Hrvol, Jr. and Paul Michael Hrvol... Bancorp, Inc. and thereby indirectly control Hardware State Bank, both of Lovington, Illinois. Board of...

75 FR 45606 - Interagency Ocean Policy Task Force-Final Recommendations of the Interagency Ocean Policy Task Force

Science.gov (United States)

2010-08-03

.../oceans or by writing to The Council on Environmental Quality, Attn: Michael Weiss, 722 Jackson Place, NW., Washington, DC 20503. FOR FURTHER INFORMATION CONTACT: Michael Weiss, Deputy Associate Director for Ocean and...

75 FR 676 - Proposed Information Collection; Comment Request; Certification, Compliance, and Enforcement...

Science.gov (United States)

2010-01-05

... information collection instrument and instructions should be directed to Michael McCabe, (202) 586-9155 or Michael.McCabe@ee.doe.gov . SUPPLEMENTARY INFORMATION: I. Abstract The Energy Policy and Conservation Act...

Use of an interdisciplinary, participatory design approach to develop a usable patient self-assessment tool in atrial fibrillation

Directory of Open Access Journals (Sweden)

MacCallum L

2013-11-01

Full Text Available Lori MacCallum,1,2 Heather McGaw,1 Nazanin Meshkat,3 Alissia Valentinis,4 Leslie Beard Ashley,5 Rajan Sacha Bhatia,3,6,7 Kaye Benson,7 Noah Ivers,6,8 Kori Leblanc,2,7 Dante Morra3,5,7 1Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, 2Leslie Dan Faculty of Pharmacy, University of Toronto, 3Department of Medicine, University of Toronto, Toronto, 4Taddle Creek Family Health Team, Toronto, 5Trillium Health Partners, Mississauga, 6Women's College Hospital, Toronto, 7Centre for Innovation in Complex Care, University Health Network, Toronto, 8Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada Abstract: After identifying that significant care gaps exist within the management of atrial fibrillation (AF, a patient-focused tool was developed to help patients better assess and manage their AF. This tool aims to provide education and awareness regarding the management of symptoms and stroke risk associated with AF, while engaging patients to identify if their condition is optimally managed and to become involved in their own care. An interdisciplinary group of health care providers and designers worked together in a participatory design approach to develop the tool with input from patients. Usability testing was completed with 22 patients of varying demographics to represent the characteristics of the patient population. The findings from usability testing interviews were used to further improve and develop the tool to improve ease of use. A physician-facing tool was also developed to help to explain the tool and provide a brief summary of the 2012 Canadian Cardiovascular Society atrial fibrillation guidelines. By incorporating patient input and human-centered design with the knowledge, experience, and medical expertise of health care providers, we have used an approach in developing the tool that tries to more effectively meet patients' needs. Keywords: patient education, atrial fibrillation, care gaps

75 FR 4622 - Qualification of Drivers; Exemption Applications; Diabetes

Science.gov (United States)

2010-01-28

.... Bauer, Michael P. Berger, William D. Blosch, Michael Bohlen, Bradley N. Brown, Victor M. Brunner, Tom L..., Eugene G. Friedman, Edward L. Gilbert, Donald W. Hansen, Joseph S. Hernandez, Corrine J. Hoffman, Robert...

Cellular computing

National Research Council Canada - National Science Library

Amos, Martyn

2004-01-01

... 120 Ron Weiss, Thomas F. Knight Jr., and Gerald Sussman 8 The Biology of Integration of Cells into Microscale and Nanoscale Systems 148 Michael L. Simpson, Timothy E. McKnight, Michael A. Guillor...

Markko Märtin : sain maailma parima kaardilugeja

Index Scriptorium Estoniae

2005-01-01

Markko Märtin rääkis ajakirjale Autosport traagilisest avariist ja hukkunud kaardilugejast Michael Parkist. Michael Parki meenutavad: Robert Reid, Paul Turner, Sebastien Loeb, David Higgins, Malcolm Wilson, Daniel Elena, David Evans

Assessment of DoD’s Central Identification Lab and the Feasibility of Increasing Identification Rates

Science.gov (United States)

2009-06-01

Lab and the Feasibility of Increasing Identification Rates David R. Graham Ashley N. Bybee Susan L. Clark-Sestak Michael S. Finnin Approved for public...Feasibility of Increasing Identification Rates David R. Graham Ashley N. Bybee Susan L. Clark-Sestak Michael S. Finnin iii PREFACE This study was...6 . A U TH O R ( S ) 5 d . P R O JE C T N O. David R. Graham, Ashley N. Bybee , Susan L. Clark-Sestak, Michael S. Finnin 5 e . TAS K N O

"Hillary - en god historie"

DEFF Research Database (Denmark)

Bjerre, Thomas Ærvold

2007-01-01

Anmeldelse af Carl Bernsteins Hillary Rodham Clinton og Michael Ehrenreichs Hillary - En amerikansk historie Udgivelsesdato: 15. november......Anmeldelse af Carl Bernsteins Hillary Rodham Clinton og Michael Ehrenreichs Hillary - En amerikansk historie Udgivelsesdato: 15. november...

Zulu nation

Energy Technology Data Exchange (ETDEWEB)

Forrest, M.; O' Keeffe, M.

2007-01-15

Michael Forest talks to Riversdale Mining's CEO Michael O'Keeffe about the company's Zululand Anthracite Colliery, which was opened in 1985, and the coal reserves in the Zululand coalfield.

Design of mitochondria-targeted colorimetric and ratiometric fluorescent probes for rapid detection of SO2 derivatives in living cells

Science.gov (United States)

Yang, Yutao; Zhou, Tingting; Bai, Bozan; Yin, Caixia; Xu, Wenzhi; Li, Wei

2018-05-01

Two mitochondria-targeted colorimetric and ratiometric fluorescent probes for SO2 derivatives were constructed based on the SO2 derivatives-triggered Michael addition reaction. The probes exhibit high specificity toward HSO3-/SO32- by interrupting their conjugation system resulting in a large ratiometric blue shift of 46-121 nm in their emission spectrum. The two well-resolved emission bands can ensure accurate detection of HSO3-. The detection limits were calculated to be 1.09 and 1.35 μM. Importantly, probe 1 and probe 2 were successfully used to fluorescence ratiometric imaging of endogenous HSO3- in BT-474 cells.

The Advanced Photon Source list of parameters

International Nuclear Information System (INIS)

Bizek, H.M.

1996-07-01

The Advanced Photon Source (APS) is a third-generation synchrotron radiation source that stores positrons in a storage ring. The choice of positrons as accelerating particles was motivated by the usual reason: to eliminate the degradation of the beam caused by trapping of positively charged dust particles or ions. The third-generation synchrotron radiation sources are designed to have low beam emittance and many straight sections for insertion devices. The parameter list is comprised of three basic systems: the injection system, the storage ring system, and the experimental facilities system. The components of the injection system are listed according to the causal flow of positrons. Below we briefly list the individual components of the injection system, with the names of people responsible for managing these machines in parentheses: the linac system; electron linac-target-positron linac (Marion White); low energy transport line from linac to the PAR (Michael Borland); positron accumulator ring or PAR (Michael Borland); low energy transport line from PAR to injector synchrotron (Michael Borland); injector synchrotron (Stephen Milton); high energy transport line from injector synchrotron to storage ring (Stephen Milton). The storage ring system, managed by Glenn Decker, uses the Chasman-Green lattice. The APS storage ring, 1104 m in circumference, has 40 periodic sectors. Six are used to house hardware and 34 serve as insertion devices. Another 34 beamlines emit radiation from bending magnets. The experimental facilities system's parameters include parameters for both an undulator and a wiggler

Response to Commentators

Directory of Open Access Journals (Sweden)

Tomasello Michael

2016-03-01

Full Text Available This paper is a reply to the comments by Henrike Moll, Glenda Satne, Ladislav Koreň and Michael Schmitz on Michael Tomasello, A Natural History of Human Thinking (Harvard University Press, 2014.

ISSN 2073 ISSN 2073-9990 East Cent. Afr. J. surg. (Online) 9990 ...

African Journals Online (AJOL)

Prof Kakande

Afr. J. surg. ..... September/October 2003. 3. Hardin R, Stevenson M, Downie W, Wilson G. Assessment of clinical competence using objective ... Michael J. Griesser, Matthew C. Beran, David C. Flanigan, Michael Quackenbush, DO, Corey Van ...

Jobs

DEFF Research Database (Denmark)

Schubart, Rikke

2013-01-01

Review of the movie Jobs (Joshua Michael Stern, 2013), a drama about Steve Jobs, the founder of Apple.......Review of the movie Jobs (Joshua Michael Stern, 2013), a drama about Steve Jobs, the founder of Apple....

Reexamining Operating System Support for Database Management

OpenAIRE

Vasil, Tim

2003-01-01

In 1981, Michael Stonebraker [21] observed that database management systems written for commodity operating systems could not effectively take advantage of key operating system services, such as buffer pool management and process scheduling, due to expensive overhead and lack of customizability. The “not quite right” fit between these kernel services and the demands of database systems forced database designers to work around such limitations or re-implement some kernel functionality in user ...