LEGO products have become more complex.

Directory of Open Access Journals (Sweden)

Christoph Bartneck

Full Text Available The LEGO Group has become the largest toy company in the world and they can look back to a proud history of more than 50 years of producing bricks and other toys. Starting with a simple set of basic bricks their range of toys appeared to have increased in complexity over the years. We processed the inventories of most sets from 1955-2015 and our analysis showed that LEGO sets have become bigger, more colorful and more specialized. The vocabulary of bricks has increased significantly resulting in sets sharing fewer bricks. The increased complexity of LEGO sets and bricks enables skilled builders to design ever more amazing models but it may also overwhelm less skilled or younger builders.

LEGO Robotics: An Authentic Problem Solving Tool?

Science.gov (United States)

Castledine, Alanah-Rei; Chalmers, Chris

2011-01-01

With the current curriculum focus on correlating classroom problem solving lessons to real-world contexts, are LEGO robotics an effective problem solving tool? This present study was designed to investigate this question and to ascertain what problem solving strategies primary students engaged with when working with LEGO robotics and whether the…

On the asymptotic enumeration of LEGO structures

DEFF Research Database (Denmark)

Abrahamsen, Mikkel; Eilers, Søren

2011-01-01

We investigate experimentally the growth regimes of the number of LEGO structures that can be constructed contiguously from n blocks of equal shape and color.......We investigate experimentally the growth regimes of the number of LEGO structures that can be constructed contiguously from n blocks of equal shape and color....

Modular Lego-Electronics

KAUST Repository

Shaikh, Sohail F.; Ghoneim, Mohamed T.; Bahabry, Rabab R.; Khan, Sherjeel M.; Hussain, Muhammad Mustafa

2017-01-01

. Here, a generic manufacturable method of converting state-of-the-art complementary metal oxide semiconductor-based ICs into modular Lego-electronics is shown with unique geometry that is physically identifiable to ease manufacturing and enhance

LEGO Diorama Images

Data.gov (United States)

Allegheny County / City of Pittsburgh / Western PA Regional Data Center — We often create dioramas from LEGO bricks for use with our presentations, blogs, and social media posts. We find it's much more fun and effective to reenact...

Lego Robotics: STEM Sport of the Mind

Science.gov (United States)

Gura, Mark

2012-01-01

Lego robotics is engaging, hands-on, and encompasses every one of the NETS for Students. It also inspires a love of science, technology, engineering, and mathematics (STEM) and provides the experience students need to use digital age skills in the real world. In this article, the author discusses how schools get involved with Lego Robotics and…

A Lego version of ATLAS

CERN Multimedia

Laëtitia Pedroso

2010-01-01

There's nothing very unusual about a small child making simple objects out of Lego. But wouldn't you be surprised to learn that one six-year old has just made a life-like model of the ATLAS detector?   Bastian with his Lego ATLAS detector. © Photo provided by Kai Nicklas, Bastian's father. It all began a month ago when the boy's father was watching a video about the construction of the ATLAS detector on the Internet. He hadn't noticed that his son was watching it over his shoulder. The small boy was fascinated by what he was seeing on the computer screen and his first reaction was to exclaim: "Wow! That's a terrific machine! I think the people who built it must be really clever." The detector must have really fired his imagination because, after asking his father a few questions, he decided to make a Lego model of it. Look at the photo and you will see how closely the model he produced resembles the actual ATLAS detector. Is the little boy in question, Bastia...

LEGO Koncern 2000 - 2003 - en årsagsanalyse

OpenAIRE

Rosenberg, Morten; Özbudak, Devrim; Møller, Mads; Herneth, Daniel

2006-01-01

Denne rapport omhandler LEGO Koncernens økonomiske krise i årene 2000-2003. Vores videnskabsteoretiske er Kritisk realisme og vi bruger i projektet; en regnskabsanalyse, komparativ rapport og en PEST-analyse Denne rapport omhandler LEGO Koncernens økonomiske krise i årene 2000-2003. Vores videnskabsteoretiske er Kritisk realisme og vi bruger i projektet; en regnskabsanalyse, komparativ rapport og en PEST-analyse

LEGO-Method--New Strategy for Chemistry Calculation

Science.gov (United States)

Molnar, Jozsef; Molnar-Hamvas, Livia

2011-01-01

The presented strategy of chemistry calculation is based on mole-concept, but it uses only one fundamental relationship of the amounts of substance as a basic panel. The name of LEGO-method comes from the famous toy of LEGO[R] because solving equations by grouping formulas is similar to that. The relations of mole and the molar amounts, as small…

Lego Group: An Outsourcing Journey

DEFF Research Database (Denmark)

Larsen, Marcus Møller; Pedersen, Torben; Slepniov, Dmitrij

2010-01-01

The last years’ rather adventurous journey from 2004 to 2009 had taught the fifth-largest toy-maker in the world - the LEGO Group - the importance of managing the global supply chain effectively. In order to survive the largest internal financial crisis in its roughly 70 years of existence......, the management had, among many initiatives, decided to offshore and outsource a major chunk of its production to Flextronics. In this pursuit of rapid cost-cutting sourcing advantages, the LEGO Group planned to license out as much as 80 per cent of its production besides closing down major parts...

Using LEGO for learning fractions, supporting or distracting?

Science.gov (United States)

Rejeki, Sri; Setyaningsih, Nining; Toyib, Muhamad

2017-05-01

The role of games used for learning mathematics is still in debate. However, many research revealed that it gave positive effects on both students' motivation and performance in mathematics. Therefore, this study aims at investigating the effects of using LEGO-as one of games which students are familiar with, for learning mathematics, on both students' conceptual knowledge of fractions and students' attitude in learning mathematics. A set of learning activities consisting three meetings of fractions learning was designed for this study. The activities were mainly about solving word-context problems using LEGO as the model. Thirty students of seven grade with high-ability in mathematics and thirty two students with low-ability in mathematics were involved in this study. The data were collected through students' written works, video registration and field notes during the teaching and learning activities. The results indicate that in general the use of LEGO in learning activities support the conceptual understanding on fractions for both students with high-ability and low-ability in mathematics. Moreover, for students with low-ability in mathematics, it promotes the computational skill of fractions operation. The evidences also suggest that bringing LEGO into classroom activities improve students' motivation and engagement. However, in some cases, students were more focus on playing than learning. Therefore, teachers play important roles on providing clear pedagogical instructions about the way to use LEGO properly.

Orthognathic model surgery with LEGO key-spacer.

Science.gov (United States)

Tsang, Alfred Chee-Ching; Lee, Alfred Siu Hong; Li, Wai Keung

2013-12-01

A new technique of model surgery using LEGO plates as key-spacers is described. This technique requires less time to set up compared with the conventional plaster model method. It also retains the preoperative setup with the same set of models. Movement of the segments can be measured and examined in detail with LEGO key-spacers. Copyright © 2013 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

IMPLEMENTASI ALGORITMA BREADTH FIRST SEARCH DAN OBSTACLE DETECTION DALAM PENELUSURAN LABIRIN DINAMIS MENGGUNAKAN ROBOT LEGO

Directory of Open Access Journals (Sweden)

Adi Wibowo

2012-05-01

Full Text Available Dewasa ini perkembangan teknologi di dunia robot edukasi berkembang pesat. Robot-robot edukasi ini sering digunakan dalam riset penelitian karena kemudahan-kemudahan yang diberikannya dari segi perangkat keras. Salah satu contoh robot edukasi adalah robot LEGO Mindstorms NXT. Pada penelitian ini robot LEGO dibangun dalam bentuk robot line follower. Robot ini mampu menelusuri dan mencari jalan keluar dari labirin dinamis. Dalam menelusuri dan mencari jalan keluar, robot LEGO menggunakan algoritma Breadth First Search dan Manhattan Distance dalam memutuskan jalan mana yang harus diambil. Ketika menemui objek halangan, robot LEGO akan mengenali dan menghindari objek halangan tersebut dengan algoritma Obstacle Detection yang dimilikinya. Hasil implementasi membuktikan bahwa algoritma penelusuran labirin dinamis ini dapat diimplementasikan pada robot LEGO meskipun terdapat banyak keterbatasan dalam robot LEGO. Nowadays, the development of technology in educational robots is rapidly evolving. Educational robots are often used in research studies because they provide convenience in terms of hardware. One example is the educational robot LEGO Mindstorms NXT robot. In this research, LEGO robots built in the form of line follower robot. Robot is able to browse and find a way out of the dynamic labyrinth. In track and find a way out, LEGO robot uses an algorithm Breadth First Search and Manhattan Distance in deciding which path to take. When encountering an obstacle object, LEGO robot will recognize and avoid that obstacle objects with Obstacle Detection algorithm. The results prove that the implementation of a dynamic maze search algorithm can be implemented on a LEGO robot even though there are many limitations in LEGO robot.

Lego Car Race

Science.gov (United States)

Preston, Christine

2017-01-01

Familiar toys can be used to scaffold young children's learning about basic physics as well as guide scientific inquiry. Teachers looking for resources to engage young children and develop science inquiry skills need look no further than the toy box. In this two-part activity, children first construct a Lego® car and use it to explore the effects…

Konstruksi Genre Dalam Film “the Lego Movie”

OpenAIRE

Natalia, Vivi

2014-01-01

“The Lego Movie” adalah film animasi dari produsen film Warner Bros yang menceritakan kehidupan dan petualangan Emmet, seorang konstruksi bangunan yang salah terdeteksi sebagai orang spesial yang mampu menyelesaikan masalah dunia. Film ini adalah sebuah film yang membawa konvensi-konvensi genre yang berbeda dibanding film-film animasi lainnya. Peneliti melakukan analisis genre terhadap film “The Lego Movie” menggunakan 6 elemen menurut Jane Stoke, yaitu setting, lokasi, peristiwa naratif, plo...

LEGO: A Modular Approach to Accelerator Alignment Data Analysis

Energy Technology Data Exchange (ETDEWEB)

LeCocq, Catherine M

2003-05-14

The underlying unity of the numerous surveying computational methods is hidden by many practical differences in data acquisition. Traditional programming languages have added to the confusion by requiring programmers to describe the numeric data in very concrete and low-level structures (mostly arrays). In fact the algorithms behind all coordinate determination from surveying observations come down to basic methods of linear algebra. Lego uses the paradigm of object oriented programming (OOP) to more closely model the fundamental mathematical structures of all geodetic methods. Once the methods are in OOP form, the commonality across them becomes more obvious and a general architecture for a wide range of geodetic treatments becomes possible. This paper describes the fundamental concepts of this architecture and its advantages in terms of clarity (maintainability, testability and multi-author), portability and extensibility (observation types, resolution techniques and storage methods). The very first version of Lego was built in 1994 as a set of C routines to be used for the adjustment of theodolite data and tracker data. The routines were organized into six modules. Each module answered a specific task. The tasks had been identified as followed: general implementation, input, generic surveying formulas, statistical functions, matrix manipulation and specific resolution technique. This organization was the reason for the name Lego, but more seriously the purpose of this separation was to make Lego easily adaptable to any environment and easily expandable to new resolution techniques. At a second look, it was also a cry for being converted into a more modern language. Because C++ is primarily a superset of C, most C++ compilers have no problems compiling regular C code and may also handle a mixture of C and C++. This made the transformation of Lego very fast and painless. Up to now Lego is still using C functions for file access and dynamic memory allocation but is

LEGO: A Modular Approach to Accelerator Alignment Data Analysis

International Nuclear Information System (INIS)

LeCocq, Catherine M

2003-01-01

The underlying unity of the numerous surveying computational methods is hidden by many practical differences in data acquisition. Traditional programming languages have added to the confusion by requiring programmers to describe the numeric data in very concrete and low-level structures (mostly arrays). In fact the algorithms behind all coordinate determination from surveying observations come down to basic methods of linear algebra. Lego uses the paradigm of object oriented programming (OOP) to more closely model the fundamental mathematical structures of all geodetic methods. Once the methods are in OOP form, the commonality across them becomes more obvious and a general architecture for a wide range of geodetic treatments becomes possible. This paper describes the fundamental concepts of this architecture and its advantages in terms of clarity (maintainability, testability and multi-author), portability and extensibility (observation types, resolution techniques and storage methods). The very first version of Lego was built in 1994 as a set of C routines to be used for the adjustment of theodolite data and tracker data. The routines were organized into six modules. Each module answered a specific task. The tasks had been identified as followed: general implementation, input, generic surveying formulas, statistical functions, matrix manipulation and specific resolution technique. This organization was the reason for the name Lego, but more seriously the purpose of this separation was to make Lego easily adaptable to any environment and easily expandable to new resolution techniques. At a second look, it was also a cry for being converted into a more modern language. Because C++ is primarily a superset of C, most C++ compilers have no problems compiling regular C code and may also handle a mixture of C and C++. This made the transformation of Lego very fast and painless. Up to now Lego is still using C functions for file access and dynamic memory allocation but is

Long-term outcome of social skills intervention based on interactive LEGO play.

Science.gov (United States)

Legoff, Daniel B; Sherman, Michael

2006-07-01

LEGO building materials have been adapted as a therapeutic modality for increasing motivation to participate in social skills intervention, and providing a medium through which children with social and communication handicaps can effectively interact. A 3 year retrospective study of long-term outcome for autistic spectrum children participating in LEGO therapy (N = 60) compared Vineland Adaptive Behavior Scale socialization domain (VABS-SD) and Gilliam Autism Rating Scale social interaction subscale (GARS-SI) scores preand post-treatment with a matched comparison sample (N = 57) who received comparable non-LEGO therapy. Although both groups made significant gains on the two outcome measures, LEGO participants improved significantly more than the comparison subjects. Diagnosis and pre-treatment full-scale IQ scores did not predict outcome scores; however, Vineland adaptive behavior composite, Vineland communication domain, and verbal IQ all predicted outcome on the VABS-SD, especially for the LEGO therapy group. Results are discussed in terms of implications for methods of social skills intervention for autistic spectrum disorders.

Learning with LEGO

Science.gov (United States)

Durrani, Matin

2017-12-01

I have lost count of the number of wheezes to get people hooked on particle physics. There have been straightforward scientific accounts, personal tales of discovery, books filled with cartoons, essays and even historical vignettes. In Particle Physics Brick by Brick, science communicator Ben Still has decided to use LEGO bricks to coax readers into learning more about the subatomic world.

LEGO-inspired drug design

DEFF Research Database (Denmark)

Thanh Tung, Truong; Dao, Trong Tuan; Grifell Junyent, Marta

2018-01-01

The fungal plasma membrane H+-ATPase (Pma1p) is a potential target for the discovery of new antifungal agents. Surprisingly, no structure-activity relationship studies for small molecules targeting Pma1p have been reported. Herein, we disclose a LEGO-inspired fragment assembly strategy for design...

Anmeldelse af Eigil Lego Andersen: Dirigent og generalforsamling

DEFF Research Database (Denmark)

Werlauff, Erik

2011-01-01

Artiklen er en anmeldelse af advokat, adj. professor, dr. jur. Eigil Lego Andersens juridiske monografi om dirigenten og generalforsamlingen, herunder med lancering af en række nye afstemningsmetoder til brug for generalforsamlingen i (større) aktieselskaber.......Artiklen er en anmeldelse af advokat, adj. professor, dr. jur. Eigil Lego Andersens juridiske monografi om dirigenten og generalforsamlingen, herunder med lancering af en række nye afstemningsmetoder til brug for generalforsamlingen i (større) aktieselskaber....

Control Systems Lab Using a LEGO Mindstorms NXT Motor System

Science.gov (United States)

Kim, Y.

2011-01-01

This paper introduces a low-cost LEGO Mindstorms NXT motor system for teaching classical and modern control theories in standard third-year undergraduate courses. The LEGO motor system can be used in conjunction with MATLAB, Simulink, and several necessary toolboxes to demonstrate: 1) a modeling technique; 2) proportional-integral-differential…

Supramolecular Lego assembly towards three-dimensional multi-responsive hydrogels.

Science.gov (United States)

Ma, Chunxin; Li, Tiefeng; Zhao, Qian; Yang, Xuxu; Wu, Jingjun; Luo, Yingwu; Xie, Tao

2014-08-27

Inspired by the assembly of Lego toys, hydrogel building blocks with heterogeneous responsiveness are assembled utilizing macroscopic supramolecular recognition as the adhesion force. The Lego hydrogel provides 3D transformation upon pH variation. After disassembly of the building blocks by changing the oxidation state, they can be re-assembled into a completely new shape. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

LEGO Dimensions meets Doctor Who: Transbranding and New Dimensions of Transmedia Storytelling?

Directory of Open Access Journals (Sweden)

Matt Hills

2016-01-01

Full Text Available This article explores how the ‘toys-to-life’ videogame LEGO Dimensions (WarnerBros. Interactive Entertainment/Traveller’s Tales/The LEGO Group, 2015 mashes upmany different franchise storyworlds and brands. Specifically, I focus on how DoctorWho (BBC, 1963—, the British TV science fiction series, is licensed and transmediallyengaged with in Dimensions. I consider how the transbranding of LEGO Dimensionsappears to co-opt children’s “transgressive play” (Nørgård and Toft-Nielsen, 2014by combining intellectual properties, but actually continues to operate according tologics of shared corporate ownership where many of the combined storyworlds areultimately owned by Time Warner (placing Dimensions in competition with Disney’sown ‘toys-to-life’ game. Considering what value might accrue to the brand of DoctorWho by participating in LEGO Dimensions, I identify this as a particular example of“What If?” transmedia (Mittell, 2015, arguing that LEGO Dimensions’ Doctor Whonevertheless fluctuates in terms of its brand (inauthenticity. The Starter Pack remainscloser to LEGO Games’/Traveller’s Tales’ established format, subordinating Who, whilstthe separate Level Pack engages more precisely with Doctor Who’s history, albeit stilldisplaying some notable divergences from the TV series (Booth, 2015. Although LEGODimensions challenges influential theories of transmedia storytelling (Jenkins, 2006;Aldred, 2014, its transbranding and child/adult targeting accord with established approachesto transmedia licensing (Santo 2015 and fan-consumer socialization (Kinder1991.

Listening and Legos[TM

Science.gov (United States)

Morris, Pamela

2012-01-01

This simple exercise, performed in teams, gives students practice in listening to instructions, particularly when there are restrictions for the communication. The teams compete in a limited amount of time to build a Lego[TM] structure based on the instructions of one team member. Which team listens the best and is most successful?

FIRST LEGO League Kickoff

Science.gov (United States)

2007-01-01

Randall Hicks (right), Jacobs Technology's Education Services manager at NASA John C. Stennis Space Center, answers questions about the playing field for FIRST (For Inspiration and Recognition of Science and Technology) LEGO League's 2007 Challenge, `Power Puzzle.' More than 140 teachers, mentors, parents and students from 15 schools attended the Sept. 15 FLL season kickoff at StenniSphere, the visitor center at SSC. The teams from southern and central Mississippi and Mobile, Ala., who came to SSC heard rules for and asked questions about `Power Puzzle,' and saw robot demonstrations by Gulfport and Picayune high schools' past FIRST Robotics competitions. Using LEGO Mindstorms NXT kits, FLL teams of children ages 9-14 will spend the next three months building and programming robots to perform 'Power Puzzle's' challenge tasks, then pit them in competitions. They also will submit a research project about how energy choices impact the environment and the economy. The season will culminate at the Mississippi Championship Tournament on Dec. 8 at the Mississippi Gulf Coast Community College. FLL, considered the `little league' of the FIRST Robotics Competition, partners FIRST and the LEGO Group. Competitions aim to inspire and celebrate science and technology using real-world context and hands-on experimentation. NASA recognizes FIRST activities as an excellent hands-on method to increase student knowledge of science, engineering, technology and mathematics. Schools represented in this year's kickoff were: Madison Avenue Upper Elementary, the Mississippi Band of Choctaw Indians' Conehatta Elementary, Hattiesburg's Lillie Burney Elementary, Pearl Upper Elementary, Long Beach Middle, Oktibehha Elementary, d'Iberville Middle, Saucier's West Wortham Middle, Picayune's Nicholson Elementary and Roseland Park Baptist Church Academy, Bay St. Louis' St. Stanislaus College and Mobile's Davidson High, as well as two home-school groups from the Jackson area.

Innovation management based on proactive engagement of customers: A case study on LEGO Group. Part I: Innovation Management at Lego Group

Science.gov (United States)

Rusu, G.; Avasilcăi, S.

2015-11-01

Customers' proactive engagement in the innovation process represents a business priority for companies which adopt the open innovation business model. In such a context, it is of outmost importance for companies to use the online environment and social media, in order to create an interactive and open dialogue with customers and other important external stakeholders, achieving to gather creative solutions and innovative ideas by involving them in the process of co-creating value. Thus, the current paper is based on a case study approach, which aims to highlight the open innovation business model of the LEGO Group, one of the most successful and active company in engaging customers in submitting ideas and creative solutions for developing new products and new technologies, through online platforms. The study then proceeds to analyze the innovation management at LEGO Group, emphasizing the most important elements regarding the management team, the success and failures, the evolution of the LEGO products focusing on the innovation efforts of the company, its mission, vision, and values, emphasizing the innovation terms which guide the actions and objectives of the LEGO Group. Also, the research based on the case study approach, outlines the most important policies and strategies of the company, the organizational structure consisting of flat structures which facilitate the orientation of the team management on the innovation process and the proactive involvement of consumers and other external stakeholders in product development, highlighting also the most important activities developed by the management team in exploring the new opportunities which may occur on the market, involving customers in sharing their ideas at festivals, participating to discussions of adult fans on web-based platforms and establishing partnerships with the external stakeholders in order to create value. Moreover, the paper is focused on identifying the company's concerns regarding the

Alle ønsker sig en Lego-aktie til jul

DEFF Research Database (Denmark)

Iversen, Martin Jes

2014-01-01

Både små og store investorer får julelys i øjnene ved tanken om at eje et stykke af Lego. På sigt kunne en børsnotering gøre Danmark til et rigere land.......Både små og store investorer får julelys i øjnene ved tanken om at eje et stykke af Lego. På sigt kunne en børsnotering gøre Danmark til et rigere land....

Using LEGO Blocks for Technology-Mediated Task-Based English Language Learning

Science.gov (United States)

Gadomska, Agnieszka

2015-01-01

LEGO blocks have been played with by generations of children worldwide since the 1950s. It is undeniable that they boost creativity, eye-hand coordination, focus, planning, problem solving and many other skills. LEGO bricks have been also used by educators across the curricula as they are extremely motivating and engaging and, in effect, make…

Using a Lego-based communications simulation to introduce medical students to patient-centered interviewing.

Science.gov (United States)

Harding, S R; D'Eon, M F

2001-01-01

Teaching patient-centered interviewing skills to medical students can be challenging. We have observed that 1st-year medical students, in particular, do not feel free to concentrate on the interviewing skills because they are preoccupied with complicated technical medical knowledge. The Lego simulation we use with our 1st-year students as part of a professional-skills course overcomes that difficulty. The Lego activity is a role play analogous to a doctor-patient interview that uses identical sets of Legos for the "doctor" and for the "patients" and a small construction that represents a patient history. With a simple questionnaire, data were collected from students at different points during instruction. Results indicate that the Lego activity was very effective in helping students learn the importance of open-ended questioning. It also was rated as highly as the very dynamic interactive part of the instructional session. The effectiveness of the Lego activity may be due to the properties of analogies.

PLAYING LEGO INCREASE COGNITIVE DEVELOPMENT ON PRESCHOOL CHILD (4-5 YEARS OLD

Directory of Open Access Journals (Sweden)

Sri Utami

2017-07-01

Full Text Available Introduction: The preschool cognitive development can be stimulated with playing activity. The preschool child who stimulateless, their creativity will be checked and it can effect their cognitive development. Playing lego is one of the stimulation which give chance to the preschool child to express creativity and explorate their skill in playing construction. This research was aimed to analyze the effect of playing lego to the preschool cognitive development. Method: Quasy experimental pre post test design was used in this research. Total sample were 18 preschool child (4-5 years old. The independent variable was playing lego and the dependent variable was the cognitive development. Data were analyzed by Wilcoxon Signed Rank Test and Mann Whitney U Test with the significance α<0.05. Result: Result showed that the control group has significance level p=0.059 and the treatment group has significance level p=0.008. The result of Mann Whitney U Test showed p=0.001. Discussion: It can be concluded that playing lego can effect the preschool cognitive development in spatial factor, reasoning, memory, and perceptual speed. It can be suggested to the further research to examine the effect of playing lego to the motoric development or social development.

Lego Group: An Outsourcing Journey

DEFF Research Database (Denmark)

Larsen, Marcus Møller; Pedersen, Torben; Slepniov, Dmitrij

2010-01-01

, the management had, among many initiatives, decided to offshore and outsource a major chunk of its production to Flextronics. In this pursuit of rapid cost-cutting sourcing advantages, the LEGO Group planned to license out as much as 80 per cent of its production besides closing down major parts...

On the entropy of LEGO

DEFF Research Database (Denmark)

Durhuus, Bergfinnur; Eilers, Søren

We propose the further study of the rate of growth of the number of contiguous buildings which may be made from n LEGO blocks of the same size and color. Specializing to blocks of dimension 2x4 we give upper and lower bounds, and speculate on the true value....

Live LEGO House: a Mixed Reality Game for the Edutainment

OpenAIRE

Portalés Ricart, Cristina

2007-01-01

Gaming is a natural way of learning and multimedia technologies bring new possibilities in the field of edutainment. Live LEGO House in an interactive space to explore coexistence and multicultural factors through gaming based on the Mixed Reality(MXR)technology. The system consists basically on a physical/real house built with the LEGO blocks, which is enriched with different non-physical/virtual multimedia files, including sounds, videos and 3D animations with multicultural content. Childre...

A 'LEGO' Hybrid Photon Detector - assembled from standard mass-produced vacuum components

International Nuclear Information System (INIS)

Ferenc, Daniel; Lorenz, Eckart; Mirzoyan, Razmik

2000-01-01

Motivated primarily by the MAGIC atmospheric Cherenkov telescope project, we have developed a 'LEGO' Hybrid Photon Detector (HPD) comprising excellent focusing properties and protection against positive ion feedback. LEGO-HPD is supposed to be assembled from standard high vacuum components, which insures simplicity in the assembly procedure and reliability of operation

Project Luna Succendo: The Lunar Evolutionary Growth-Optimized (LEGO) Reactor

Science.gov (United States)

Bess, John Darrell

A final design has been established for a basic Lunar Evolutionary Growth-Optimized (LEGO) Reactor using current and near-term technologies. The LEGO Reactor is a modular, fast-fission, heatpipe-cooled, clustered-reactor system for lunar-surface power generation. The reactor is divided into subcritical units that can be safely launched within lunar shipments from the Earth, and then emplaced directly into holes drilled into the lunar regolith to form a critical reactor assembly. The regolith would not just provide radiation shielding, but serve as neutron-reflector material as well. The reactor subunits are to be manufactured using proven and tested materials for use in radiation environments, such as uranium-dioxide fuel, stainless-steel cladding and structural support, and liquid-sodium heatpipes. The LEGO Reactor system promotes reliability, safety, and ease of manufacture and testing at the cost of an increase in launch mass per overall rated power level and a reduction in neutron economy when compared to a single-reactor system. A single unshielded LEGO Reactor subunit has an estimated mass of approximately 448 kg and provides 5 kWe using a free-piston Stirling space converter. The overall envelope for a single unit with fully extended radiator panels has a height of 8.77 m and a diameter of 0.50 m. The subunits can be placed with centerline distances of approximately 0.6 m in a hexagonal-lattice pattern to provide sufficient neutronic coupling while allowing room for heat rejection and interstitial control. A lattice of six subunits could provide sufficient power generation throughout the initial stages of establishing a lunar outpost. Portions of the reactor may be neutronically decoupled to allow for reduced power production during unmanned periods of base operations. During later stages of lunar-base development, additional subunits may be emplaced and coupled into the existing LEGO Reactor network Future improvements include advances in reactor control

Calling all LEGO lovers! Add a mini control room to your collection

CERN Multimedia

Katarina Anthony

2015-01-01

The mini LHC Lego project launched in March (see here) now has almost 6,000 supporters - well on its way to the 10,000 votes needed for it to (hopefully!) hit store shelves. This week, the project added a new feature to its line: a mini control centre! The new LEGO Control centre, featuring operators "Kerstin" and "Marco".   The mini LHC project is the brainchild of ATLAS PhD student Nathan Readioff, who designed Lego replicas of the LHC and the ALICE, ATLAS, CMS and LHCb experiments on a micro scale. Each detector model is small enough to fit in the palm of your hand but crammed with detailed internal systems revealed by cutaway walls. Every major detector component is represented by a Lego piece. Now, Nathan has created a control centre to complement the mini LHC project. This would be an add-on feature for Lego’s consideration, should they decide to develop the accelerator into a box set. “The control centre is ...

Bright bricks, dark play: On the impossibility of studying LEGO

OpenAIRE

Giddings, S.

2014-01-01

It is generally recognized that the pleasures of LEGO do not end once the instructions in a particular set have been followed and the model depicted on the box is accurately realized. Generations of children have —just as the manufacturers intended— pulled apart the pristine model and begun again, making new vehicles, environments and creatures. The new set joins the larger box of LEGO full of older bricks, and is mixed and hybridized. This hybridization has become particularly evident in rec...

Implementation of Reconfigurable Manufacturing Systems, the Case of The LEGO Group

DEFF Research Database (Denmark)

Wang, Ying; Bilberg, Arne; Hadar, Ronen

of reconfigurable manufacturing systems (RMS). A literature review is made to describe the advantages and core characteristics of RMS. Based on the theory, a conceptual model is developed to analyze where RMS would be most suitable and have most benefits in The LEGO Group. Finally, the conclusion is drawn based...... on the analysis through the model. Keywords: Reconfigurable Manufacturing Systems, Conceptual Model of RMS, Production of The LEGO Group...

FIRST LEGO League announces State Championship winners

Science.gov (United States)

2007-01-01

PEAK Home School Network Team 1832 'Techno Warriors' of Brandon sport the Champions Award they won during the Dec. 8 FIRST (For Inspiration and Recognition of Science and Technology) LEGO League 2007 Mississippi Championship Tournament.

LEGO for Two-Party Secure Computation

DEFF Research Database (Denmark)

Nielsen, Jesper Buus; Orlandi, Claudio

2009-01-01

This paper continues the recent line of work of making Yao’s garbled circuit approach to two-party computation secure against an active adversary. We propose a new cut-and-choose based approach called LEGO (Large Efficient Garbled-circuit Optimization): It is specifically aimed at large circuits...

Race to improve student understanding of uncertainty: Using LEGO race cars in the physics lab

Science.gov (United States)

Parappilly, Maria; Hassam, Christopher; Woodman, Richard J.

2018-01-01

Laboratories using LEGO race cars were developed for students in an introductory physics topic with a high early drop-out rate. In a 2014 pilot study, the labs were offered to improve students' confidence with experiments and laboratory skills, especially uncertainty propagation. This intervention was extended into the intro level physics topic the next year, for comparison and evaluation. Considering the pilot study, we subsequently adapted the delivery of the LEGO labs for a large Engineering Mechanics cohort. A qualitative survey of the students was taken to gain insight into their perception of the incorporation of LEGO race cars into physics labs. For Engineering, the findings show that LEGO physics was instrumental in teaching students the measurement and uncertainty, improving their lab reporting skills, and was a key factor in reducing the early attrition rate. This paper briefly recalls the results of the pilot study, and how variations in the delivery yielded better learning outcomes. A novel method is proposed for how LEGO race cars in a physics lab can help students increase their understanding of uncertainty and motivate them towards physics practicals.

Liquid-handling Lego robots and experiments for STEM education and research

OpenAIRE

Gerber, Lukas C.; Calasanz-Kaiser, Agnes; Hyman, Luke; Voitiuk, Kateryna; Patil, Uday; Riedel-Kruse, Ingmar H.

2017-01-01

Liquid-handling robots have many applications for biotechnology and the life sciences, with increasing impact on everyday life. While playful robotics such as Lego Mindstorms significantly support education initiatives in mechatronics and programming, equivalent connections to the life sciences do not currently exist. To close this gap, we developed Lego-based pipetting robots that reliably handle liquid volumes from 1 ml down to the sub-μl range and that operate on standard laboratory plasti...

Transforming LEGO for the Digital Economy

DEFF Research Database (Denmark)

Andersen, Peter; Ross, Jeanne

2016-01-01

processes. The goal of the new transformation is “to become a digital company.” Although the company already looked digital in 2016, management felt it had not become digital—in its products and processes. This case describes the LEGO Group’s journey to become a successful digital company....

LEGO: a novel method for gene set over-representation analysis by incorporating network-based gene weights.

Science.gov (United States)

Dong, Xinran; Hao, Yun; Wang, Xiao; Tian, Weidong

2016-01-11

Pathway or gene set over-representation analysis (ORA) has become a routine task in functional genomics studies. However, currently widely used ORA tools employ statistical methods such as Fisher's exact test that reduce a pathway into a list of genes, ignoring the constitutive functional non-equivalent roles of genes and the complex gene-gene interactions. Here, we develop a novel method named LEGO (functional Link Enrichment of Gene Ontology or gene sets) that takes into consideration these two types of information by incorporating network-based gene weights in ORA analysis. In three benchmarks, LEGO achieves better performance than Fisher and three other network-based methods. To further evaluate LEGO's usefulness, we compare LEGO with five gene expression-based and three pathway topology-based methods using a benchmark of 34 disease gene expression datasets compiled by a recent publication, and show that LEGO is among the top-ranked methods in terms of both sensitivity and prioritization for detecting target KEGG pathways. In addition, we develop a cluster-and-filter approach to reduce the redundancy among the enriched gene sets, making the results more interpretable to biologists. Finally, we apply LEGO to two lists of autism genes, and identify relevant gene sets to autism that could not be found by Fisher.

Programación de LEGO MindStorms bajo GNU/Linux

OpenAIRE

Matellán Olivera, Vicente; Heras Quirós, Pedro de las; Centeno González, José; González Barahona, Jesús

2002-01-01

GNU/Linux sobre un ordenador personal es la opción libre preferida por muchos desarrolladores de aplicaciones, pero también es una plataforma de desarrollo muy popular para otros sistemas, incluida la programación de robots, en particular es muy adecuada para jugar con los LEGO Mindstorms. En este artículo presentaremos las dos opciones más extendidas a la hora de programar estos juguetes: NQC y LegOS. NQC es una versión reducida de C que permite el desarrollo rápido de programas ...

A Basic LEGO Reactor Design for the Provision of Lunar Surface Power

International Nuclear Information System (INIS)

John Darrell Bess

2008-01-01

A final design has been established for a basic Lunar Evolutionary Growth-Optimized (LEGO) Reactor using current and near-term technologies. The LEGO Reactor is a modular, fast-fission, heatpipe-cooled, clustered-reactor system for lunar-surface power generation. The reactor is divided into subcritical units that can be safely launched with lunar shipments from Earth, and then emplaced directly into holes drilled into the lunar regolith to form a critical reactor assembly. The regolith would not just provide radiation shielding, but serve as neutron-reflector material as well. The reactor subunits are to be manufactured using proven and tested materials for use in radiation environments, such as uranium-dioxide fuel, stainless-steel cladding and structural support, and liquid-sodium heatpipes. The LEGO Reactor system promotes reliability, safety, and ease of manufacture and testing at the cost of an increase in launch mass per overall rated power level and a reduction in neutron economy when compared to a single-reactor system. A single unshielded LEGO Reactor subunit has an estimated mass of approximately 448 kg and provides approximately 5 kWe. The overall envelope for a single subunit with fully extended radiator panels has a height of 8.77 m and a diameter of 0.50 m. Six subunits could provide sufficient power generation throughout the initial stages of establishing a lunar outpost. Portions of the reactor may be neutronically decoupled to allow for reduced power production during unmanned periods of base operations. During later stages of lunar-base development, additional subunits may be emplaced and coupled into the existing LEGO Reactor network, subject to lunar base power demand. Improvements in reactor control methods, fuel form and matrix, shielding, as well as power conversion and heat rejection techniques can help generate an even more competitive LEGO Reactor design. Further modifications in the design could provide power generative opportunities for

Color dithering methods for LEGO-like 3D printing

Science.gov (United States)

Sun, Pei-Li; Sie, Yuping

2015-01-01

Color dithering methods for LEGO-like 3D printing are proposed in this study. The first method is work for opaque color brick building. It is a modification of classic error diffusion. Many color primaries can be chosen. However, RGBYKW is recommended as its image quality is good and the number of color primary is limited. For translucent color bricks, multi-layer color building can enhance the image quality significantly. A LUT-based method is proposed to speed the dithering proceeding and make the color distribution even smoother. Simulation results show the proposed multi-layer dithering method can really improve the image quality of LEGO-like 3D printing.

A Day at FIRST Lego League

Science.gov (United States)

McIntyre, Nancy

2012-01-01

This article features an after-school FIRST Lego League (FLL) program at Chaminade Middle School in Chatsworth, California, USA. The after-school FLL program feeds into the high school FIRST Robotics Competition (FRC) program wherein aspiring young engineers come to the high school team with several years of FLL experience. Through the FLL…

Wave propagation in complex structures with LEGO

NARCIS (Netherlands)

Lancellotti, V.; Hon, de B.P.; Tijhuis, A.G.

2012-01-01

We present the extension of the linear embedding via Green's operators (LEGO) scheme to problems that involve elementary sources localized inside complex structures made of different dielectric media with inclusions. We show how this new feature allows solving problems of wave propagation within,

Exploring New Firm Creation Out of Brand Communities: The Case of LEGO

DEFF Research Database (Denmark)

Hienerth, Christoph; Lettl, Christopher; Biskjaer, Michael Mose

2011-01-01

In the field of new product development, brand communities have attracted a great deal of attention from both academics and practitioners as a means of facilitating consumer-producer co-creation processes. In this paper, we extend the line of research on brand communities to the field...... brand community enjoys a broader range of LEGO products and services. Our findings reveal the emergence of a hybrid organizational form in which new business ideas are neither exploited solely within the boundaries of the focal producer firm, nor pursued by fully independent new firms alone. We observe...... of entrepreneurship studies by examining the conditions under which new firms emerge out of these social networks. Our empirical setting is the global LEGO brand community. As a well-known pioneering firm that is constantly experimenting with new ways of collaborating with its fan and customer base, LEGO recently...

Spiral CT scanning technique in the detection of aspiration of LEGO foreign bodies.

Science.gov (United States)

Applegate, K E; Dardinger, J T; Lieber, M L; Herts, B R; Davros, W J; Obuchowski, N A; Maneker, A

2001-12-01

Radiolucent foreign bodies (FBs) such as plastic objects and toys remain difficult to identify on conventional radiographs of the neck and chest. Children may present with a variety of respiratory complaints, which may or may not be due to a FB. To determine whether radiolucent FBs such as plastic LEGOs and peanuts can be seen in the tracheobronchial tree or esophagus using low-dose spiral CT, and, if visible, to determine the optimal CT imaging technique. Multiple spiral sequences were performed while varying the CT parameters and the presence and location of FBs in either the trachea or the esophagus first on a neck phantom and then a cadaver. Sequences were rated by three radiologists blinded to the presence of a FB using a single scoring system. The LEGO was well visualized in the trachea by all three readers (both lung and soft-tissue windowing: combined sensitivity 89 %, combined specificity 89 %) and to a lesser extent in the esophagus (combined sensitivity 31 %, combined specificity 100 %). The peanut was not well visualized (combined sensitivity LEGO was 120 kV, 90 mA, 3-mm collimation, 0.75 s/revolution, and 2.0 pitch. This allowed for coverage of the cadaver tracheobronchial tree (approximately 11 cm) in about 18 s. Although statistical power was low for detecting significant differences, all three readers noted higher average confidence ratings with lung windowing among 18 LEGO-in-trachea scans. Rapid, low-dose spiral CT may be used to visualize LEGO FBs in the airway or esophagus. Peanuts were not well visualized.

Elite weapons for lego fanatics build working handcuffs, body armor, batons, sunglasses, and the world's hardest hitting brick guns

CERN Document Server

Hüdepohl, Martin

2015-01-01

The last LEGO brick weapon construction book and design guide you'll ever need, Elite Weapons for LEGO Fanatics features building instructions for thirteen fully functional LEGO masterpieces, including the monstrous, 27-inch-long Dinosaur Superior, a fully automatic combat rifle that can puncture aluminum cans, and a highly detailed HK G3 brick replica. Also featuring a helmet, a baton, handcuffs, sunglasses, and a grappling hook gun, which allows you to retrieve distant objects without ever leaving your seat, Elite Weapons for LEGO Fanatics includes a chapter on how to find the LEGO pieces you need and a comic book story featuring a hero using the weapons in action. LEGO fans of all ages and skill levels will find a treasure trove of models, including: • Hammerhead Jr., a single-shot crossbow and it's big brother, the heavy-duty Hammerhead Sr. • Panzer Pod combat helmet • KlopSTOCK baton • Melody, a rubber-firing machine pistol • Nice-1, a pocket-sized pistol that packs a punch • Chinahook harpoon gun ...

Particle physics brick by brick atomic and subatomic physics explained... in LEGO

CERN Document Server

Still, Ben

2017-01-01

Using LEGO (R) blocks to create a uniquely visual and clear depiction of the way our universe is put together. This is the perfect introduction to the enigmatic and fascinating world of Quantum Physics.Our story starts with the Big Bang, and along the way, the constructs and interactions within and among atoms and sub-atomic particles, and the forces that play upon them, are clearly explained, with each LEGO (R) block representing a different atomic or sub-atomic particle. The different colours and size denote what that particle is and its relationship with the other 'building blocks'.Each chapter is presented in digestible chunks, using toy building blocks to illustrate the ideas and experiments that have led to some of the biggest discoveries of the past 150 years.Soon you'll be able to construct every element in the Universe using a box of LEGO (R) and this book!

Modulating ectopic gene expression levels by using retroviral vectors equipped with synthetic promoters.

Science.gov (United States)

Ferreira, Joshua P; Peacock, Ryan W S; Lawhorn, Ingrid E B; Wang, Clifford L

2011-12-01

The human cytomegalovirus and elongation factor 1α promoters are constitutive promoters commonly employed by mammalian expression vectors. These promoters generally produce high levels of expression in many types of cells and tissues. To generate a library of synthetic promoters capable of generating a range of low, intermediate, and high expression levels, the TATA and CAAT box elements of these promoters were mutated. Other promoter variants were also generated by random mutagenesis. Evaluation using plasmid vectors integrated at a single site in the genome revealed that these various synthetic promoters were capable of expression levels spanning a 40-fold range. Retroviral vectors were equipped with the synthetic promoters and evaluated for their ability to reproduce the graded expression demonstrated by plasmid integration. A vector with a self-inactivating long terminal repeat could neither reproduce the full range of expression levels nor produce stable expression. Using a second vector design, the different synthetic promoters enabled stable expression over a broad range of expression levels in different cell lines. The online version of this article (doi:10.1007/s11693-011-9089-0) contains supplementary material, which is available to authorized users.

LEGO, Legoland og Billund Lalandia nr. 2

DEFF Research Database (Denmark)

Leth Pasgaard, Jens Chr.

2007-01-01

kant af Ribe Amt. Ud over LEGO koncernens produktionsudflytning påvirkes Ny Billund Kommune endvidere af lukningen af Danish Crowns slagteri i Grindsted, hvor 700 arbejdspladser for nyligt blev nedlagt. Det er således forståeligt at kommunen byder nye investorer velkommen. Kommunen har potentialet til...

Innovation management based on proactive engagement of customers: A case study on LEGO Group. Part II: Challenge of engaging the digital customer

Science.gov (United States)

Avasilcăi, S.; Rusu, G.

2015-11-01

To foster the development of innovative products and new technologies, nowadays companies use an open innovation system, encouraging stakeholders to contribute, using the companies’ online platforms for open innovation or social media, bringing and sharing creative solutions and ideas in order to respond to challenging needs the company directly expresses. Accordingly, the current research continues the analysis of the LEGO Group innovation efforts, aiming to provide a case study approach based on describing the most important projects and online instruments company uses to interact with customers and other external stakeholders. Thus, by analysing the experience of the company in developing projects of involving stakeholders in the innovation processes, the article emphasizes the objective of these past projects developed by LEGO Group, outlining their objectives regarding the focus on the product or process innovation, the team management and stakeholders involved in the innovation actions and the results they obtained. Moreover, the case study highlights the features of the most important online instruments LEGO Group uses at the moment for engaging LEGO fans, children, parents, and other external stakeholders in developing new LEGO sets. Thus, LEGO online instruments provide the opportunity for customers to be creative and to respond to LEGO management team challenges. Accordingly, LEGO involve customers in bringing innovative ideas for LEGO sets through LEGO Ideas instrument, which aims to engage customers in submitting projects, voting and supporting ideas and also sharing them on social media. Also, the research emphasizes the role of supporting the open dialogue and interaction with customers and other external stakeholders through LEGO.com Create & Share Galleries instrument, using their creativity to upload innovative models in the public galleries. The continuous challenges LEGO launches for their fans create a long-term connection between company and

Block Party: Legos in the Library

Science.gov (United States)

Klebanoff, Abbe

2009-01-01

Toys don't belong in the library. That's probably what some people still think. But the author's library outside Philadelphia was having such a hard time attracting boys who had outgrown storytime that he and his colleagues decided to try something new. So his school started a Lego club. Since their June 2008 kickoff, they've been amazed by how…

The parametric resonance—from LEGO Mindstorms to cold atoms

Science.gov (United States)

Kawalec, Tomasz; Sierant, Aleksandra

2017-07-01

We show an experimental setup based on a popular LEGO Mindstorms set, allowing us to both observe and investigate the parametric resonance phenomenon. The presented method is simple but covers a variety of student activities like embedded software development, conducting measurements, data collection and analysis. It may be used during science shows, as part of student projects and to illustrate the parametric resonance in mechanics or even quantum physics, during lectures or classes. The parametrically driven LEGO pendulum gains energy in a spectacular way, increasing its amplitude from 10° to about 100° within a few tens of seconds. We provide also a short description of a wireless absolute orientation sensor that may be used in quantitative analysis of driven or free pendulum movement.

The parametric resonance—from LEGO Mindstorms to cold atoms

International Nuclear Information System (INIS)

Kawalec, Tomasz; Sierant, Aleksandra

2017-01-01

We show an experimental setup based on a popular LEGO Mindstorms set, allowing us to both observe and investigate the parametric resonance phenomenon. The presented method is simple but covers a variety of student activities like embedded software development, conducting measurements, data collection and analysis. It may be used during science shows, as part of student projects and to illustrate the parametric resonance in mechanics or even quantum physics, during lectures or classes. The parametrically driven LEGO pendulum gains energy in a spectacular way, increasing its amplitude from 10° to about 100° within a few tens of seconds. We provide also a short description of a wireless absolute orientation sensor that may be used in quantitative analysis of driven or free pendulum movement. (paper)

Liquid-handling Lego robots and experiments for STEM education and research.

Directory of Open Access Journals (Sweden)

Lukas C Gerber

2017-03-01

Full Text Available Liquid-handling robots have many applications for biotechnology and the life sciences, with increasing impact on everyday life. While playful robotics such as Lego Mindstorms significantly support education initiatives in mechatronics and programming, equivalent connections to the life sciences do not currently exist. To close this gap, we developed Lego-based pipetting robots that reliably handle liquid volumes from 1 ml down to the sub-μl range and that operate on standard laboratory plasticware, such as cuvettes and multiwell plates. These robots can support a range of science and chemistry experiments for education and even research. Using standard, low-cost household consumables, programming pipetting routines, and modifying robot designs, we enabled a rich activity space. We successfully tested these activities in afterschool settings with elementary, middle, and high school students. The simplest robot can be directly built from the widely used Lego Education EV3 core set alone, and this publication includes building and experiment instructions to set the stage for dissemination and further development in education and research.

Liquid-handling Lego robots and experiments for STEM education and research.

Science.gov (United States)

Gerber, Lukas C; Calasanz-Kaiser, Agnes; Hyman, Luke; Voitiuk, Kateryna; Patil, Uday; Riedel-Kruse, Ingmar H

2017-03-01

Liquid-handling robots have many applications for biotechnology and the life sciences, with increasing impact on everyday life. While playful robotics such as Lego Mindstorms significantly support education initiatives in mechatronics and programming, equivalent connections to the life sciences do not currently exist. To close this gap, we developed Lego-based pipetting robots that reliably handle liquid volumes from 1 ml down to the sub-μl range and that operate on standard laboratory plasticware, such as cuvettes and multiwell plates. These robots can support a range of science and chemistry experiments for education and even research. Using standard, low-cost household consumables, programming pipetting routines, and modifying robot designs, we enabled a rich activity space. We successfully tested these activities in afterschool settings with elementary, middle, and high school students. The simplest robot can be directly built from the widely used Lego Education EV3 core set alone, and this publication includes building and experiment instructions to set the stage for dissemination and further development in education and research.

Spiral CT scanning technique in the detection of aspiration of LEGO foreign bodies

International Nuclear Information System (INIS)

Applegate, K.E.; Dardinger, J.T.; Herts, B.R.; Davros, W.J.; Obuchowski, N.A.; Lieber, M.L.; Maneker, A.

2001-01-01

Background:. Radiolucent foreign bodies (FBs) such as plastic objects and toys remain difficult to identify on conventional radiographs of the neck and chest. Children may present with a variety of respiratory complaints, which may or may not be due to a FB. Objective: To determine whether radiolucent FBs such as plastic LEGOs and peanuts can be seen in the tracheobronchial tree or esophagus using low-dose spiral CT, and, if visible, to determine the optimal CT imaging technique. Materials and methods: Multiple spiral sequences were performed while varying the CT parameters and the presence and location of FBs in either the trachea or the esophagus first on a neck phantom and then a cadaver. Sequences were rated by three radiologists blinded to the presence of a FB using a single scoring system. Results: The LEGO was well visualized in the trachea by all three readers (both lung and soft-tissue windowing: combined sensitivity 89 %, combined specificity 89 %) and to a lesser extent in the esophagus (combined sensitivity 31 %, combined specificity 100 %). The peanut was not well visualized (combined sensitivity < 35 %). The optimal technique for visualizing the LEGO was 120 kV, 90 mA, 3-mm collimation, 0.75 s/revolution, and 2.0 pitch. This allowed for coverage of the cadaver tracheobronchial tree (approximately 11 cm) in about 18 s. Although statistical power was low for detecting significant differences, all three readers noted higher average confidence ratings with lung windowing among 18 LEGO-in-trachea scans. Conclusion: Rapid, low-dose spiral CT may be used to visualize LEGO FBs in the airway or esophagus. Peanuts were not well visualized. (orig.)

Lego Serious Play in Law

Directory of Open Access Journals (Sweden)

Frederico de Andrade Gabrich

2016-12-01

Full Text Available The legal education is not fully following the significant changes in society in the XXI century, and this determines significant lack of student motivation. The teaching methodologies used in legal courses continued to follow the teacher's knowledge and books, grounded in instructionism. It takes the development and application of new teaching methodologies that favor the change of the dominant mental model, systems thinking, innovation and real problems solution that motivate students for learning. The Lego Serious

How LEGO Built the Foundations and Enterprise Capabilities for Digital Leadership

DEFF Research Database (Denmark)

El Sawy, Omar; Henrik, Amsinck; Kræmmergaard, Pernille

2016-01-01

We define digital leadership as doing the right things for the strategic success of digitalization for the enterprise and its business ecosystem. Digital leadership means thinking differently about business strategy, business models, the IT function, enterprise platforms, mindsets and skill sets......, and the workplace. Based on the decade-long digitalization journey and experiences of the LEGO Group, this article provides insights on building the foundations for enhancing enterprise capabilities for digital leadership. Leveraging digitalization is one of the LEGO Group’s four strategic priorities...... and is fundamental to it being a world leader in its industry...

Generation NXT: Building Young Engineers with LEGOs

Science.gov (United States)

Karp, T.; Gale, R.; Lowe, L. A.; Medina, V.; Beutlich, E.

2010-01-01

This paper describes key success factors for the implementation and development of a LEGO robotics engineering outreach program for elementary school students in West Texas. The outreach program not only aims at getting young students excited about engineering but at the same time aims at improving retention rates among electrical and computer…

Designing and implementing nervous system simulations on LEGO robots.

Science.gov (United States)

Blustein, Daniel; Rosenthal, Nikolai; Ayers, Joseph

2013-05-25

We present a method to use the commercially available LEGO Mindstorms NXT robotics platform to test systems level neuroscience hypotheses. The first step of the method is to develop a nervous system simulation of specific reflexive behaviors of an appropriate model organism; here we use the American Lobster. Exteroceptive reflexes mediated by decussating (crossing) neural connections can explain an animal's taxis towards or away from a stimulus as described by Braitenberg and are particularly well suited for investigation using the NXT platform.(1) The nervous system simulation is programmed using LabVIEW software on the LEGO Mindstorms platform. Once the nervous system is tuned properly, behavioral experiments are run on the robot and on the animal under identical environmental conditions. By controlling the sensory milieu experienced by the specimens, differences in behavioral outputs can be observed. These differences may point to specific deficiencies in the nervous system model and serve to inform the iteration of the model for the particular behavior under study. This method allows for the experimental manipulation of electronic nervous systems and serves as a way to explore neuroscience hypotheses specifically regarding the neurophysiological basis of simple innate reflexive behaviors. The LEGO Mindstorms NXT kit provides an affordable and efficient platform on which to test preliminary biomimetic robot control schemes. The approach is also well suited for the high school classroom to serve as the foundation for a hands-on inquiry-based biorobotics curriculum.

History and Educational Potential of LEGO Mindstorms NXT

Directory of Open Access Journals (Sweden)

Memet ÜÇGÜL

2013-01-01

Full Text Available Abstract: Educational usage of the robotics has accelerated recently because of educational potential of robotics has been recognized by educators and popularity of international robotics tournaments. Many university and schools prepare technology and robotics related summer schools for children. LEGO Mindstorms NXT is the most popular and commonly used robotics set for educational purposes. This robot sets rooted to Seymour Papert’s LOGO studies which have much influence Instructional Technology in 1960’s. This study aims to present a literature review on educational potential of LEGO Mindstorms NXT robotics sets. Robotics mainly used in education for supporting the STEM (Science, Technology, Engineering and Mathematics education. Most of the related studies resulted with positive effects of the robotics activities in STEM education. Robotics also used in education to increase some skills of the children such as discovery learning, critical thinking and social skills.Özet - LEGO Mindstorms NXT’lerin Tarihi ve Eğitsel Potansiyeli: Robotların eğitsel amaçlarla kullanımı giderek artmaktadır. Eğitimcilerin robotların eğitsel potansiyelinin farkına varmaları ve uluslararası robot turnuvalarının popülerlik kazanmasının robotların eğitsel kullanımına katkısı büyüktür. Birçok üniversite ve okul, teknoloji ve robotlar konulu yaz kampları düzenlemektedirler. LEGO Mindstorms NXT en popüler ve en çok kullanılan eğitsel robot setleridir. Bu robot setlerinin geçmişi, Seymour Papert’in LOGO çalışmalarına dayanmaktadır. Bu çalışmaların 1960’larda eğitim teknolojisine büyük etkileri olmuştur. Bu tarama çalışmasının amacı son zamanlarda eğitimcilerin ilgisini çeken, robotların eğitsel amaçlarla kullanımına yönelik çalışmaları inceleyerek, LEGO Mindstorms NXT robot setlerinin  eğitim amaçlı kullanım potansiyellerinin belirlenmesidir. Robotlar eğitimde en çok FTMM (Fen, Teknoloji

A LEGO Mindstorms Brewster angle microscope

Science.gov (United States)

Fernsler, Jonathan; Nguyen, Vincent; Wallum, Alison; Benz, Nicholas; Hamlin, Matthew; Pilgram, Jessica; Vanderpoel, Hunter; Lau, Ryan

2017-09-01

A Brewster Angle Microscope (BAM) built from a LEGO Mindstorms kit, additional LEGO bricks, and several standard optics components, is described. The BAM was built as part of an undergraduate senior project and was designed, calibrated, and used to image phospholipid, cholesterol, soap, and oil films on the surface of water. A BAM uses p-polarized laser light reflected off a surface at the Brewster angle, which ideally yields zero reflectivity. When a film of different refractive index is added to the surface a small amount of light is reflected, which can be imaged in a microscope camera. Films of only one molecule (approximately 1 nm) thick, a monolayer, can be observed easily in the BAM. The BAM was used in a junior-level Physical Chemistry class to observe phase transitions of a monolayer and the collapse of a monolayer deposited on the water surface in a Langmuir trough. Using a photometric calculation, students observed a change in thickness of a monolayer during a phase transition of 7 Å, which was accurate to within 1 Å of the value determined by more advanced methods. As supplementary material, we provide a detailed manual on how to build the BAM, software to control the BAM and camera, and image processing software.

Scaling limits for the Lego discrepancy

International Nuclear Information System (INIS)

Hameren, Andre van; Kleiss, Ronald

1999-01-01

For the Lego discrepancy with M bins, which is equivalent with a χ 2 -statistic with M bins, we present a procedure to calculate the moment generating function of the probability distribution perturbatively if M and N, the number of uniformly and randomly distributed data points, become large. Furthermore, we present a phase diagram for various limits of the probability distribution in terms of the standardized variable if M and N become infinite

MiniLEGO

DEFF Research Database (Denmark)

Frederiksen, Tore Kasper; Jakobsen, Thomas Pelle; Nielsen, Jesper Buus

2013-01-01

One of the main tools to construct secure two-party computation protocols are Yao garbled circuits. Using the cut-and-choose technique, one can get reasonably efficient Yao-based protocols with security against malicious adversaries. At TCC 2009, Nielsen and Orlandi [28] suggested to apply cut......-and-choose at the gate level, while previously cut-and-choose was applied on the circuit as a whole. This idea allows for a speed up with practical significance (in the order of the logarithm of the size of the circuit) and has become known as the “LEGO” construction. Unfortunately the construction in [28] is based...... on a specific number-theoretic assumption and requires public-key operations per gate of the circuit. The main technical contribution of this work is a new XOR-homomorphic commitment scheme based on oblivious transfer, that we use to cope with the problem of connecting the gates in the LEGO construction. Our...

LEGO A Modular Approach to Accelerator Alignment Data Analysis

CERN Document Server

Lecocq, C M

2003-01-01

The underlying unity of the numerous surveying computational methods is hidden by many practical differences in data acquisition. Traditional programming languages have added to the confusion by requiring programmers to describe the numeric data in very concrete and low-level structures (mostly arrays). In fact the algorithms behind all coordinate determination from surveying observations come down to basic methods of linear algebra. Lego uses the paradigm of object oriented programming (OOP) to more closely model the fundamental mathematical structures of all geodetic methods. Once the methods are in OOP form, the commonality across them becomes more obvious and a general architecture for a wide range of geodetic treatments becomes possible. This paper describes the fundamental concepts of this architecture and its advantages in terms of clarity (maintainability, testability and portability and extensibility (observation types, resolution techniques and storage methods). The very first version of Lego was bu...

An Exploration of the Nanoworld with LEGO Bricks

Science.gov (United States)

Campbell, Dean J.; Miller, Josiah D.; Bannon, Stephen J.; Obermaier, Lauren M.

2011-01-01

LEGO bricks can be used for a number of demonstrations of chemical structures and properties, especially at the nanoscale level. These bricks can also be used to model instrumentation that probes these structures and properties. Detailed resources about many of these demonstrations are located on the extensive Web site "Exploring the Nanoworld…

Lego Bricks and the Octet Rule: Molecular Models for Biochemical Pathways with Plastic, Interlocking Toy Bricks

Science.gov (United States)

Lin, Henry J.; Lehoang, Jennifer; Kwan, Isabel; Baghaee, Anita; Prasad, Priya; Ha-Chen, Stephanie J.; Moss, Tanesha; Woods, Jeremy D.

2018-01-01

The 8 studs on a 2 × 4 Lego brick conveniently represent the outer shell of electrons for carbon, nitrogen, and oxygen atoms. We used Lego bricks to model these atoms, which are then joined together to form molecules by following the Lewis octet rule. A variety of small biological molecules can be modeled in this way, such as most amino acids,…

METODE BERMAIN LEGO DALAM UPAYA MENUMBUHKEMBANGKAN KECERDASAN KINESTETIK PADA ANAK USIA DINI (Sudi Kasus di Lembaga Pendidikan Manusia Unggul

Directory of Open Access Journals (Sweden)

Fitria Yulianti Ningtyas

2018-01-01

Full Text Available Penelitian ini membahas tentang upaya menumbuhkembangkan kecerdasan kinestetik pada anak usia dini melalui metode bermain Lego di Lembaga Pendidikan Manusia Unggul. Melalui permainan Lego, anak yang memiliki gaya belajar kinestetik akan terstimulasi kecerdasan dan kemampuannya, terutama kecerdasan kinestetiknya. Sebab pada dasarnya, anak dengan gaya belajar kinestetik, memiliki kelebihan dalam ruang gerak serta berlebih energinya. Sehingga saat belajar, anak membutuhkan ruang yang cukup luas, serta permainan yang menantang. Penelitian ini bertujuan: 1 Untuk mengetahui dan menganalisis bagaimana langkah-langkah dalam menerapkan metode bermain Lego dalam upaya menumbuhkembangkan kecerdasan kinestetik pada anak usia dini di Lembaga Pendidikan Manusia Unggul. 2 Untuk mengetahui dan menganalisis bagaimana pelaksanaan dalam menerapkan metode bermain Lego dalam upaya menumbuhkembangkan kecerdasan kinestetik pada anak usia dini di Lembaga Manusia Unggul. 3 Untuk mengetahui dan menganalisis dampak dan hasil dari penerapan metode bermain Lego dalam upaya menumbuhkembangkan kecerdasan kinestetik pada anak usia dini di Lembaga Pendidikan Manusia Unggul. 4 Untuk mengetahui dan menganalisis apa saja faktor pendukung dan penghambat dalam menerapkan metode bermain Lego dalam upaya menumbuhkembangkan kecerdasan kinestetik pada anak usia dini di Lembaga Manusia Unggul. Penelitian ini menggunakan pendekatan kualitatif naturalistik. Ciri yang menonjol dari penelitian ini adalah cara pengamatan dan pengumpulan datanya dilakukan dalam latar/setting alamiah. Artinya tanpa memanipulasi subyek yang diteliti. Penelitian ini mencakup juga keyakinan terhadap sifat dasar dari realitas (yang diamati, hubungan antara orang yang mencoba mengetahui sesuatu (peneliti dan hal yang mereka coba ketahui (yang diteliti, peranan/pengaruh dari nilai-nilai (yang dianut peneliti dan variable-variabel lainnya yang serupa itu.Kajian data pada penelitian ini didapat dari hasil pengamatan

PENGARUH PENGGUNAAN BUKU AJAR BERBASIS STEM BERBANTUAN LEGO MINDSTORM EV3 TERHADAP PEMAHAMAN KONSEP MOMENTUM SISWA

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Ratih Mega Ayu Afifah

2017-10-01

Full Text Available The purpose of this research is to figure out the effect of using STEM (Science, Technology, Engineering, and Mathematic based textbook that assisted by using LEGO mindstorm EV3 toward the students’s understanding of momentum subject. The design of this research that is pretest-postest group design. The Samples are composed of 12 students from experimental class and 12 students from control class. The results of this research show that the conceptual understanding of experimental class that using STEM-based textbook that assisted by using LEGO mindstorm EV3 is beter than the understanding of control class which using the conventional textbook in the ordinary class. The implication of this research is applying this textbook to measure the other cognitive dimention such as reasoning. Abstrak Tujuan penelitian ini adalah untuk mengetahui pengaruh penggunaan buku ajar berbasis STEM (Science, Technology, Engineering, dan Mathematics berbantuan LEGO mindstorm EV3 dalam pembelajaran fisika terhadap pemahaman konsep siswa pada materi momentum. Penelitian ini menggunakan desain eksperimen pretest postest group design. Sampel penelitian terdiri dari 12  siswa kelompok eksperimen dan 12 siswa kelompok kontrol. Berdasarkan hasil analisis menunjukkan bahwa pemahaman konsep kelompok siswa yang menggunakan buku ajar berbasis STEM berbantuan LEGO mindstorm EV3 secara signifikan lebih meningkat dibandingkan dengan kelompok yang menggunakan buku yang biasa digunakan di sekolah. Hasil penelitian menunjukkan bahwa penggunaan buku ajar berbasis STEM berbantuan robot LEGO mindstorm EV3 dapat meningkatkan pemahaman konsep siswa pada materi momentum. Implikasi pada penelitian ini adalah menerapkan buku ajar tersebut untuk mengukur dimensi kognitif lainnya seperti penalaran.

The Lego Story: Remolding Education Policy and Practice

Science.gov (United States)

Pirrie, Anne

2017-01-01

The aim of this article is to develop a more nuanced understanding of the complex nature of learning as it relates to both the educational and social aims of education as manifested in contemporary European education policy. The article explores tensions in education policy and practice by exploring the evolution of the global brand Lego. The…

Lightweight Expression of Granular Objects (LEGO) Content Modeling Using the SNOMED CT Observables Model to Represent Nursing Assessment Data.

Science.gov (United States)

Johnson, Christie

2016-01-01

This poster presentation presents a content modeling strategy using the SNOMED CT Observable Model to represent large amounts of detailed clinical data in a consistent and computable manner that can support multiple use cases. Lightweight Expression of Granular Objects (LEGOs) represent question/answer pairs on clinical data collection forms, where a question is modeled by a (usually) post-coordinated SNOMED CT expression. LEGOs transform electronic patient data into a normalized consumable, which means that the expressions can be treated as extensions of the SNOMED CT hierarchies for the purpose of performing subsumption queries and other analytics. Utilizing the LEGO approach for modeling clinical data obtained from a nursing admission assessment provides a foundation for data exchange across disparate information systems and software applications. Clinical data exchange of computable LEGO patient information enables the development of more refined data analytics, data storage and clinical decision support.

Use of LEGO as a therapeutic medium for improving social competence.

Science.gov (United States)

LeGoff, Daniel B

2004-10-01

A repeated-measures, waiting list control design was used to assess efficacy of a social skills intervention for autistic spectrum children focused on individual and group LEGO play. The intervention combined aspects of behavior therapy, peer modeling and naturalistic communication strategies. Close interaction and joint attention to task play an important role in both group and individual therapy activities. The goal of treatment was to improve social competence (SC) which was construed as reflecting three components: (1) motivation to initiate social contact with peers; (2) ability to sustain interaction with peers for a period of time: and (3) overcoming autistic symptoms of aloofness and rigidity. Measures for the first two variables were based on observation of subjects in unstructured situations with peers; and the third variable was assessed using a structured rating scale, the SI subscale of the GARS. Results revealed significant improvement on all three measures at both 12 and 24 weeks with no evidence of gains during the waiting list period. No gender differences were found on outcome, and age of clients was not correlated with outcome. LEGO play appears to be a particularly effective medium for social skills intervention, and other researchers and clinicians are encouraged to attempt replication of this work, as well as to explore use of LEGO in other methodologies, or with different clinical populations.

LEGO therapy and the social use of language programme: an evaluation of two social skills interventions for children with high functioning autism and Asperger Syndrome.

Science.gov (United States)

Owens, Gina; Granader, Yael; Humphrey, Ayla; Baron-Cohen, Simon

2008-11-01

LEGO therapy and the Social Use of Language Programme (SULP) were evaluated as social skills interventions for 6-11 year olds with high functioning autism and Asperger Syndrome. Children were matched on CA, IQ, and autistic symptoms before being randomly assigned to LEGO or SULP. Therapy occurred for 1 h/week over 18 weeks. A no-intervention control group was also assessed. Results showed that the LEGO therapy group improved more than the other groups on autism-specific social interaction scores (Gilliam Autism Rating Scale). Maladaptive behaviour decreased significantly more in the LEGO and SULP groups compared to the control group. There was a non-significant trend for SULP and LEGO groups to improve more than the no-intervention group in communication and socialisation skills.

Enriching K-12 Science and Mathematics Education Using LEGOs

Science.gov (United States)

Williams, Keeshan; Igel, Irina; Poveda, Ronald; Kapila, Vikram; Iskander, Magued

2012-01-01

This paper presents a series of illustrative LEGO Mindstorms-based science and math activities, developed under an NSF GK-12 Fellows project, for elementary, middle, and high school grades. The activities, developed by engineering and science graduate Fellows in partnership with K-12 teachers, are grade appropriate, address pertinent learning…

Build Your Own Particle Detector. Education and outreach through ATLAS LEGO models and events

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00220289; The ATLAS collaboration

2016-01-01

To support the outreach activities of ATLAS institutes and to grasp people’s attention in science exhibitions and during public events, a very detailed model of the experiment built entirely out of LEGO bricks as well as an outreach programme using LEGO bricks to get people to think about particle detectors and involve them into a conversation about particle physics in general have been created. A large LEGO model, consisting of about 9500 pieces, has been exported to more than 55 ATLAS institutes and has been used in numerous exhibitions to explain the proportion and composition of the experiment to the public. As part of the Build Your Own Particle Detector programme (byopd.org) more than 15 events have been conducted, either involving a competition to design and build the best particle detector from a random pile of pieces or to take part in the construction of one of the large models, as part of a full day outreach event. Recently, miniature models of all four main LHC experiments, that will be used at ...

LEGO bricks used as chemotactic chambers: evaluation by a computer-assisted image analysis technique.

Science.gov (United States)

Azzarà, A; Chimenti, M

2004-01-01

One of the main techniques used to explore neutrophil motility, employs micropore filters in chemotactic chambers. Many new models have been proposed, in order to perform multiple microassays in a rapid, inexpensive and reproducible way. In this work, LEGO bricks have been used as chemotactic chambers in the evaluation of neutrophil random motility and chemotaxis and compared with conventional Boyden chambers in a "time-response" experiment. Neutrophil motility throughout the filters was evaluated by means of an image-processing workstation, in which a dedicated algorithm recognizes and counts the cells in several fields and focal planes throughout the whole filter; correlates counts and depth values; performs a statistical analysis of data; calculates the true value of neutrophil migration; determines the distribution of cells; and displays the migration pattern. By this method, we found that the distances travelled by the cells in conventional chambers and in LEGO bricks were perfectly identical, both in random migration and under chemotactic conditions. Moreover, no interference with the physiological behaviour of neutrophils was detectable. In fact, the kinetics of migration was identical both in random migration (characterized by a gaussian pattern) and in chemotaxis (characterized by a typical stimulation peak, previously identified by our workstation). In conclusion, LEGO bricks are extremely precise devices. They are simple to use and allow the use of small amounts of chemoattractant solution and cell suspension, supplying by itself a triplicate test. LEGO bricks are inexpensive, fast and suitable for current diagnostic activity or for research investigations in every laboratory.

The KINA neutronic module of the LEGO code for steady-state and transient PWR plant simulations

International Nuclear Information System (INIS)

Nicolopoulos, D.; Pollacchini, L.; Vimercati, G.; Spelta, S.

1989-01-01

The Automation Research Center (CRA) of ENEl has implemented some models for analyzing both incidental and operational transients in PWR power plants. For such models an axial neutron kinetics module characterized by high computational efficency with adequate results accuracy was called for. CISE has been entrusted with the task of implementing such a module named KINA and based on IQS (Improved Quasi Static) method, to be included in the library of LEGO modular code used by CRA to set up PWR power models. Moreover, The KINA module has been adapted to the neutron constants computing model developed by the EdF-SEPTEN, which has been using and improving the LEGO code for a long time in cooperation with ENEL-CRA. In this paper, after some remarks on the LEGO code, a general description of KINA neutronic module is given. The resylts of a preliminary validation activity of KINA for an EdF 1300 MWe PWR plant are also presented

Another brick in the whole: estrategias de adaptación, remediación y transmediación en LEGO Batman: La Película

Directory of Open Access Journals (Sweden)

Sergio ALBALADEJO-ORTEGA

2018-01-01

Full Text Available El estreno en 2014 de La Lego Película (The Lego Movie, Phil Lord y Chris Miller supuso un importante hito en la historia de la empresa danesa LEGO, erigiendo el filme como pieza clave de la estrategia transmediática que empezaba a tomar forma en el ámbito cinematográfico. Aquel filme, en el que el personaje de Batman gozaba de un especial protagonismo, ha dado paso a un particular spin-off que, bajo el título LEGO Batman: La Película (The LEGO Batman Movie, Chris McKay, 2017, repite algunas de las fórmulas puestas en práctica en La Lego Película e introduce otras nuevas de igual o mayor interés desde un punto de vista intertextual. Este artículo se aproxima al largometraje del superhéroe de DC Comics atendiendo a las particulares estrategias de adaptación, remediación y transmediación que lleva a cabo. A través del análisis de los componentes narrativos que constituyen la propuesta del filme, así como de su puesta en relación con los presentes en los textos impresos, audiovisuales y videolúdicos pertenecientes a la franquicia LEGO Batman, se estudian las distintas estrategias que posibilitan la interconexión entre ellos y moldean el ‘macrorrelato’ (Scolari, 2009 que, de manera paradigmática, toma forma en la narrativa transmediática resultante.

Maternal Experience of Lego Therapy in Families with Children with Autism Spectrum Conditions: What Is the Impact on Family Relationships?

Science.gov (United States)

Peckett, Helen; MacCallum, Fiona; Knibbs, Jacky

2016-01-01

This study aimed to explore mothers' experience of implementing Lego Therapy at home within the family. Following a Lego Therapy training session, mothers carried out hourly sessions with their child with an autism spectrum condition and the child's sibling, once a week, for 6 weeks. Mothers were interviewed following the intervention, and the…

Modelamiento y programación de un juego de legos en un entorno de brealidad virtual

OpenAIRE

Arboleda, Freddy; Laica, Ricardo; Loor, Magdalena; García, Sixto

2010-01-01

This project seeks by the use of the techniques of Virtual Reality to create a virtual world of a traditional game of Lego blocks, in order to check the applicability of the concepts learned throughout the topic. The present abstract specifies the general ideas on the modeling, design and implementation of an application of Virtual Reality of Lego blocks. First, we focus in the creation of the 3D objects and scenes, which are going to constitute the virtual environment. Later, we are going t...

LEGO-based Robotics in Higher Education: 15 Years of Student Creativity

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Ethan Danahy

2014-02-01

Full Text Available Our goal in this article is to reflect on the role LEGO robotics has played in college engineering education over the last 15 years, starting with the introduction of the RCX in 1998 and ending with the introduction of the EV3 in 2013. By combining a modular computer programming language with a modular building platform, LEGO Education has allowed students (of all ages to become active leaders in their own education as they build everything from animals for a robotic zoo to robots that play children's games. Most importantly, it allows all students to develop different solutions to the same problem to provide a learning community. We look first at how the recent developments in the learning sciences can help in promoting student learning in robotics. We then share four case studies of successful college-level implementations that build on these developments.

Long-term LEGO therapy with humanoid robot for children with ASD

NARCIS (Netherlands)

Barakova, E.I.; Bajracharya, P.; Willemsen, M.H.J.; Lourens, T.; Huskens, B.

2015-01-01

To utilise the knowledge gained from highly specialised domains as autism therapy to robot-based interactive training platforms, an innovative design approach is needed. We present the process of content creation and co-design of LEGO therapy for children with autism spectrum disorders performed by

"Creative Blocs": Action Research Study on the Implementation of Lego as a Tool for Reflective Practice with Social Care Practitioners

Science.gov (United States)

Cavaliero, Tamsin

2017-01-01

The aim of this study is to investigate whether Lego could be used as a tool for reflective practice with social care practitioners (SCPs) and student practitioners. This article outlines an action research study conducted in an institute of higher education in Ireland. Findings from this study suggest that Lego can be used to support student…

Does Lego Training Stimulate Pupils' Ability to Solve Logical Problems?

Science.gov (United States)

Lindh, Jorgen; Holgersson, Thomas

2007-01-01

The purpose of this study is to investigate the effect of a one-year regular robotic toys (lego) training on school pupils' performance. The underlying pedagogical perspective is the "constructionist theory," where the main idea is that knowledge is constructed in the mind of the pupil by active learning. The investigation has been made…

The Serious Use of Play and Metaphor: Legos and Labyrinths

Science.gov (United States)

James, Alison; Brookfield, Stephen

2013-01-01

In this paper the authors wish to examine kinesthetic forms of learning involving the body and the physical realm. The authors look at two particular techniques; using Legos to build metaphorical models and living the physical experience of metaphors in the shape of labyrinth-walking and its attendant activities. The authors begin by discussing…

Towards Lego Snapping; Integration of Carbon Nanotubes and Few-Layer Graphene

Science.gov (United States)

Nasseri, Mohsen; Boland, Mathias; Farrokhi, M. Javad; Strachan, Douglas

Integration of semiconducting, conducting, and insulating nanomaterials into precisely aligned complicated systems is one of the main challenges to the ultimate size scaling of electronic devices, which is a key goal in nanoscience and nanotechnology. This integration could be made more effective through controlled alignment of the crystallographic lattices of the nanoscale components. Of the vast number of materials of atomically-thin materials, two of the sp2 bonded carbon structures, graphene and carbon nanotubes, are ideal candidates for this type of application since they are built from the same backbone carbon lattice. Here we report carbon nanotube and graphene hybrid nanostructures fabricated through their catalytic synthesis and etching. The growth formations we have investigated through various high-resolution microscopy techniques provide evidence of lego-snapped interfaces between nanotubes and graphene into device-relevant orientations. We will finish with a discussion of the various size and energy regimes relevant to these lego-snapped interfaces and their implications on developing these integrated formations.

PENERAPAN LEGO BRICKS DALAM PEMBELAJARAN SEBAGAI STRATEGI UNTUK MENINGKATKAN KECERDASAN MATEMATIS SISWA DALAM MENGHITUNG BILANGAN BERPANGKAT

Directory of Open Access Journals (Sweden)

Mutia Rahma Setyani

2017-12-01

Full Text Available Penelitian ini bertujuan untuk mengetahui hasil pembelajaran dan mendeskripsikan kecerdasan matematis siswa dalam menghitung bilangan berpangkat setelah menggunakan lego bricks pada siswa kelas III Tahassus MIS Ta’allamul Huda. Penelitian ini menggunakan Penelitian Tindakan Kelas ini dengan model pembelajaran Cooperative Learning. Subjek penelitian adalah siswa kelas III ahassus MIS a’allamul Huda yang berjumlah 24 siswa. Data dikumpulkan melalui observasi dan wawancara, selanjutnya dianalisis secara kualitatif. Hasil penelitian menunjukkan bahwa keberhasilan penerapan lego bricks pada perhitungan bilangan berpangkat meningkat pada setiap siklusnya. Pada tahap Pra Siklus, hanya 40% siswa yang lulus dalam mengerjakan soal-soal dari bilangan berpangkat, kemudian pada Siklus I berdasarkan hasil observasi didapatkan kenaikan yang signifikan yaitu 80% siswa yang lulus dalam mengerjakan soal mengenai bilangan berpangkat. Masih ada 20% siswa yang masih kesulitan dalam mengerjakan soal tersebut. Selanjutnya setelah dilakukan perbaikan, pada Siklus II didapat kenaikan yang luar biasa yaitu seluruh kelompok siswa lulus dalam mengerjakan soal mengenai bilangan berpangkat. Hal tersebut dibuktikan kembali melalui hasil post test pada tahap Pasca Siklus dimana nilai seluruh siswa berada diatas kriteria ketuntasan minimum, yaitu 85-100 sehingga penerapan lego bricks untuk meningkatkan kecerdasan matematis siswa dalam menghitung bilangan berpangkat dikatakan berhasil.

Organizational System for the LEGO WeDo 2.0 Robotics System

Science.gov (United States)

Dolecheck, Suzann Hagan; Ewers, Timothy

2017-01-01

In this article, we explain an organizational system for the new LEGO Education WeDo 2.0 Core Set used in 4-H robotics; in school enrichment, afterschool, and other youth robotics programs; and by hobbyists. The system presented is for organizing WeDo parts into a translucent parts tray that includes part names and numbers. The article provides…

Expressivity in Open-ended Constructive Play: Building and Playing Musical Lego Instruments

DEFF Research Database (Denmark)

Jakobsen, Kasper; Stougaard, Jeppe; Petersen, Marianne Graves

2016-01-01

This paper presents the findings from a case study in designing for open-ended constructive play for children. The study is based on a workshop where more that 150 children in ages 3-13 built and played their own musical instruments from Lego. The children used different sensors for playing...

The educational affordances of Lego-based play in primary school

Directory of Open Access Journals (Sweden)

Luisa Salmaso

2013-12-01

Full Text Available Questo articolo presenta un’esperienza didattica attuata in una classe prima e in una classe seconda della Scuola Primaria mediante l’utilizzo di mattoncini Lego. Al termine di questo percorso è stato possibile delineare alcuni elementi utili per sostenere l’efficacia del gioco a favore dello sviluppo delle abilità visuo-spaziali e di pianificazione, anche in una prospettiva inclusiva e di pari opportunità di genere.

Combined prediction model for supply risk in nuclear power equipment manufacturing industry based on support vector machine and decision tree

International Nuclear Information System (INIS)

Shi Chunsheng; Meng Dapeng

2011-01-01

The prediction index for supply risk is developed based on the factor identifying of nuclear equipment manufacturing industry. The supply risk prediction model is established with the method of support vector machine and decision tree, based on the investigation on 3 important nuclear power equipment manufacturing enterprises and 60 suppliers. Final case study demonstrates that the combination model is better than the single prediction model, and demonstrates the feasibility and reliability of this model, which provides a method to evaluate the suppliers and measure the supply risk. (authors)

A model of Alto Lazio boiling water reactor using the LEGO code balance of plant simulation

International Nuclear Information System (INIS)

Spelta, S.; Garbossa, G.B.

1989-01-01

An extensive effort has been made at the Italian National Electricity Board (ENEL) to construct and validate a LEGO model capable of simulating the operational transients of the Alto Lazio Nuclear Station, a two twin-units site with BWR/6 class reactors, rated at 2894 MWt and with Mark III containment. LEGO is a modular package developed at the Research and development Department of the Italian National Electricity Board (CRA-ENEL) for computer aided modeling of fossil-fired and nuclear steam power plants. In this paper a system analysis model capable of describing steady-state and transient performance of the Balance of Plant (BOP) of the Alto Lazio Power Station is presented. This is one of two companion papers devoted to the description of the overall plant model including both the Nuclear Steam Supply System (NSSS) and the BOP. In the paper, after a brief summary of the main LEGO characteristics, a description of the BOP lay-out is presented. The overall model, which has been set-up, including control systems and automation, is very detailed and consists of almost 2000 differential or algebraic equations. After a brief description of the mathematical model, two significant transients obtained using the overall model are presented and discussed

Fast generation of macro basis functions for LEGO through the adaptive cross approximation

NARCIS (Netherlands)

Lancellotti, V.

2015-01-01

We present a method for the fast generation of macro basis functions in the context of the linear embedding via Green's operators approach (LEGO) which is a domain decomposition technique based on the combination of electromagnetic bricks in turn described by means of scattering operators. We show

‘Everything is awesome’ : The LEGO movie and the affective politics of security

NARCIS (Netherlands)

Goggin, J.

2017-01-01

Scholarship on the finance-security nexus has typically been concerned with ‘first order’ phenomena, such as the interpenetration of the finance and security sectors. This article contributes to the debate by turning to an apparent epiphenomenon, namely The LEGO Movie, and using it to address some

Culture's building blocks: investigating cultural evolution in a LEGO construction task.

Science.gov (United States)

McGraw, John J; Wallot, Sebastian; Mitkidis, Panagiotis; Roepstorff, Andreas

2014-01-01

ONE OF THE MOST ESSENTIAL BUT THEORETICALLY VEXING ISSUES REGARDING THE NOTION OF CULTURE IS THAT OF CULTURAL EVOLUTION AND TRANSMISSION: how a group's accumulated solutions to invariant challenges develop and persevere over time. But at the moment, the notion of applying evolutionary theory to culture remains little more than a suggestive trope. Whereas the modern synthesis of evolutionary theory has provided an encompassing scientific framework for the selection and transmission of biological adaptations, a convincing theory of cultural evolution has yet to emerge. One of the greatest challenges for theorists is identifying the appropriate time scales and units of analysis in order to reduce the intractably large and complex phenomenon of "culture" into its component "building blocks." In this paper, we present a model for scientifically investigating cultural processes by analyzing the ways people develop conventions in a series of LEGO construction tasks. The data revealed a surprising pattern in the selection of building bricks as well as features of car design across consecutive building sessions. Our findings support a novel methodology for studying the development and transmission of culture through the microcosm of interactive LEGO design and assembly.

A line follower robot implementation using Lego's Mindstorms Kit and Q-Learning

Directory of Open Access Journals (Sweden)

Hector-Gabriel Acosta-Mesa

2012-03-01

Full Text Available Un problema común al trabajar con robots móviles es que la fase de programación puede ser un proceso largo, costoso y difícil para los programadores. Los Algoritmos de Aprendizaje por Refuerzo ofrecen uno de los marcos de trabajo más generales en el ámbito de aprendizaje de máquina. Este trabajo presenta un enfoque usando el algoritmo de Q-Learning en un robot Lego para que aprenda "por sí mismo" a seguir una línea negra dibujada en una superficie blanca. El entorno de programación utilizado en este trabajo es Matlab.A common problem working with mobile robots is that programming phase could be a long, expensive and heavy process for programmers. The reinforcement learning algorithms offer one of the most general frameworks in learning subjects. This work presents an approach using the Q-Learning algorithm on a Lego robot in order for it to learn by itself how to follow a blackline drawn down on a white surface, using Matlab [5] as programming environment.

Teaching of Computer Science Topics Using Meta-Programming-Based GLOs and LEGO Robots

Science.gov (United States)

Štuikys, Vytautas; Burbaite, Renata; Damaševicius, Robertas

2013-01-01

The paper's contribution is a methodology that integrates two educational technologies (GLO and LEGO robot) to teach Computer Science (CS) topics at the school level. We present the methodology as a framework of 5 components (pedagogical activities, technology driven processes, tools, knowledge transfer actors, and pedagogical outcomes) and…

Long-Term Outcome of Social Skills Intervention Based on Interactive LEGO[C] Play

Science.gov (United States)

Legoff, Daniel B.; Sherman, Michael

2006-01-01

LEGO[C] building materials have been adapted as a therapeutic modality for increasing motivation to participate in social skills intervention, and providing a medium through which children with social and communication handicaps can effectively interact. A 3 year retrospective study of long-term outcome for autistic spectrum children participating…

Comparison of the LEGO Mindstorms NXT and EV3 Robotics Education Platforms

Science.gov (United States)

Sherrard, Ann; Rhodes, Amy

2014-01-01

The release of the latest LEGO Mindstorms EV3 robotics platform in September 2013 has provided a dilemma for many youth robotics leaders. There is a need to understand the differences in the Mindstorms NXT and EV3 in order to make future robotics purchases. In this article the differences are identified regarding software, hardware, sensors, the…

Modular Lego-Electronics

KAUST Repository

Shaikh, Sohail F.

2017-10-24

Electronic system components have thousands of individual field effect transistors (FETs) interconnected executing dedicated functions. Assembly yield of >80% will guarantee system failure since a single interconnect failure will result in undesired performance. Hence, a paradigm shift is needed in the self-assembly or integration of state-of-the-art integrated circuits (ICs) for a physically compliant system. Traditionally, most ICs share same geometry with only variations in dimensions and packaging. Here, a generic manufacturable method of converting state-of-the-art complementary metal oxide semiconductor-based ICs into modular Lego-electronics is shown with unique geometry that is physically identifiable to ease manufacturing and enhance throughput. Various geometries at the backside of the silicon die and on the destination site having the same geometry with relaxed dimension (up to 50 µm extra) allow targeted site binding like DNA assembly. Different geometries, angles, and heights for different modules provide a unique identity to each of the ICs. A two-level geometric combination presented here helps in maintaining the uniqueness of individual module to assemble at exact matching site like a perfect lock-and-key model. The assembled ICs offer uncompromised electrical performance, higher yield, and fabrication ease. In future, this method can further be expanded for fluidic assisted self-assembly.

Business Process Innovation: The LEGO Case

DEFF Research Database (Denmark)

Møller, Charles; Hansen, P.K.

2006-01-01

Most organizations today are required not only to establish effective business processes but they are required to accommodate for changing business conditions at an increasing rate. Many business processes extend beyond the boundary of the enterprise into the supply chain and the information...... process innovation (BPI) in future organizations. This paper explores the applicability of one particular methodology for Business Process Innovation to deal with the challenge that the LEGO organization is facing with the alignment of their product development process and their supply chain. The paper...... infrastructure therefore is critical. Today nearly every business relies on their Enterprise System (ES) for process integration and the future generations of Enterprise Systems will increasingly be driven by business process models. Consequently process modelling and improvement will become vital for business...

DIME Students Show Off their Lego(TM) Challenge Creation

Science.gov (United States)

2002-01-01

Two students show the Lego (TM) Challenge device they designed and built to operate in the portable drop tower demonstrator as part of the second Dropping in a Microgravity Environment (DIME) competition held April 23-25, 2002, at NASA's Glenn Research Center. Competitors included two teams from Sycamore High School, Cincinnati, OH, and one each from Bay High School, Bay Village, OH, and COSI Academy, Columbus, OH. DIME is part of NASA's education and outreach activities. Details are on line at http://microgravity.grc.nasa.gov/DIME_2002.html.

Introduction to autonomous mobile robotics using Lego Mindstorms NXT

Science.gov (United States)

Akın, H. Levent; Meriçli, Çetin; Meriçli, Tekin

2013-12-01

Teaching the fundamentals of robotics to computer science undergraduates requires designing a well-balanced curriculum that is complemented with hands-on applications on a platform that allows rapid construction of complex robots, and implementation of sophisticated algorithms. This paper describes such an elective introductory course where the Lego Mindstorms NXT kits are used as the robot platform. The aims, scope and contents of the course are presented, and the design of the laboratory sessions as well as the term projects, which address several core problems of robotics and artificial intelligence simultaneously, are explained in detail.

The Impact of Lean Thinking on Workforce Motivation: A Success Factor at LEGO Manufacturing Ltd.

Directory of Open Access Journals (Sweden)

Oláh Judit

2017-06-01

Full Text Available Several enterprises have tried to introduce the lean approach in order to enhance competitiveness. However, the only successful ones were the companies which understood that lean is not only about methods and tools, but the people using them: employees. The only way an enterprise can become a lean organisation is if all of its members deeply identify with the organisation’s principles, which is then manifested in all decisions and actions of the organisation. The aim of this study is to present the practical use of the lean approach in the Nyíregyháza plant of LEGO. Based on the questionnaire results and our observations, we present the current situation of LEGO in accordance with the same points and compare it to an ideal situation. We then make improvement recommendations in all cases when negative changes were observed.

Highly Manufacturable Deep (Sub-Millimeter) Etching Enabled High Aspect Ratio Complex Geometry Lego-Like Silicon Electronics

KAUST Repository

Ghoneim, Mohamed T.; Hussain, Muhammad Mustafa

2017-01-01

A highly manufacturable deep reactive ion etching based process involving a hybrid soft/hard mask process technology shows high aspect ratio complex geometry Lego-like silicon electronics formation enabling free-form (physically flexible

Using LEGO NXT Mobile Robots with LabVIEW for Undergraduate Courses on Mechatronics

Science.gov (United States)

Gomez-de-Gabriel, J. M.; Mandow, A.; Fernandez-Lozano, J.; Garcia-Cerezo, A.

2011-01-01

The paper proposes lab work and student competitions based on the LEGO NXT Mindstorms kits and standard LabVIEW. The goal of this combination is to stimulate design and experimentation with real hardware and representative software in courses where mobile robotics is adopted as a motivating platform to introduce mechatronics competencies. Basic…

Electromagnetic modelling of large complex 3-D structures with LEGO and the eigencurrent expansion method

NARCIS (Netherlands)

Lancellotti, V.; Hon, de B.P.; Tijhuis, A.G.

2009-01-01

Linear embedding via Green's operators (LEGO) is a computational method in which the multiple scattering between adjacent objects - forming a large composite structure - is determined through the interaction of simple-shaped building domains, whose electromagnetic (EM) behavior is accounted for by

Improving the Teaching of Discrete-Event Control Systems Using a LEGO Manufacturing Prototype

Science.gov (United States)

Sanchez, A.; Bucio, J.

2012-01-01

This paper discusses the usefulness of employing LEGO as a teaching-learning aid in a post-graduate-level first course on the control of discrete-event systems (DESs). The final assignment of the course is presented, which asks students to design and implement a modular hierarchical discrete-event supervisor for the coordination layer of a…

Form, Content, and Gender Differences in Lego[R] Block Creations by Japanese Adolescents

Science.gov (United States)

Kato, Daiki; Morita, Miyako

2009-01-01

This study examined general features of Lego block creations produced by Japanese adolescents with no known mental health disorders. The block creations of 33 participants were assessed for form, content, and gender differences. Time spent on the task, amount of area covered, and quantity and types of blocks used were measured and correlated with…

Culture’s building blocks: investigating cultural evolution in a LEGO construction task

Science.gov (United States)

McGraw, John J.; Wallot, Sebastian; Mitkidis, Panagiotis; Roepstorff, Andreas

2014-01-01

One of the most essential but theoretically vexing issues regarding the notion of culture is that of cultural evolution and transmission: how a group’s accumulated solutions to invariant challenges develop and persevere over time. But at the moment, the notion of applying evolutionary theory to culture remains little more than a suggestive trope. Whereas the modern synthesis of evolutionary theory has provided an encompassing scientific framework for the selection and transmission of biological adaptations, a convincing theory of cultural evolution has yet to emerge. One of the greatest challenges for theorists is identifying the appropriate time scales and units of analysis in order to reduce the intractably large and complex phenomenon of “culture” into its component “building blocks.” In this paper, we present a model for scientifically investigating cultural processes by analyzing the ways people develop conventions in a series of LEGO construction tasks. The data revealed a surprising pattern in the selection of building bricks as well as features of car design across consecutive building sessions. Our findings support a novel methodology for studying the development and transmission of culture through the microcosm of interactive LEGO design and assembly. PMID:25309482

Culture’s building blocks: investigating cultural evolution in a LEGO construction task

Directory of Open Access Journals (Sweden)

John Joseph Mcgraw

2014-09-01

Full Text Available One of the most essential but theoretically vexing issues regarding the notion of culture is that of cultural evolution and transmission: how a group’s accumulated solutions to invariant challenges develop and persevere over time. But at the moment, the notion of applying evolutionary theory to culture remains little more than a suggestive trope. Whereas the modern synthesis of evolutionary theory has provided an encompassing scientific framework for the selection and transmission of biological adaptations, a convincing theory of cultural evolution has yet to emerge. One of the greatest challenges for theorists is identifying the appropriate time scales and units of analysis in order to reduce the intractably large and complex phenomenon of culture into its component building blocks. In this paper, we present a model for scientifically investigating cultural processes by analyzing the ways people develop conventions in a series of LEGO construction tasks. The data revealed a surprising pattern in the selection of building bricks as well as features of car design across consecutive building sessions. Our findings support a novel methodology for studying the development and transmission of culture through the microcosm of interactive LEGO design and assembly.

LEGO[R] Therapy and the Social Use of Language Programme: An Evaluation of Two Social Skills Interventions for Children with High Functioning Autism and Asperger Syndrome

Science.gov (United States)

Owens, Gina; Granader, Yael; Humphrey, Ayla; Baron-Cohen, Simon

2008-01-01

LEGO[R] therapy and the Social Use of Language Programme (SULP) were evaluated as social skills interventions for 6-11 year olds with high functioning autism and Asperger Syndrome. Children were matched on CA, IQ, and autistic symptoms before being randomly assigned to LEGO or SULP. Therapy occurred for 1 h/week over 18 weeks. A no-intervention…

The Use of Lego Technologies in Elementary Teacher Preparation

Science.gov (United States)

Hadjiachilleos, Stella; Avraamidou, Lucy; Papastavrou, Stavros

2013-10-01

The need to reform science teacher preparation programs has been pointed out in research (Bryan and Abell in J Res Sci Teach 36:121-140, 1999; Bryan and Atwater in Sci Educ 8(6):821-839, 2002; Harrington and Hathaway in J Teach Educ 46(4):275-284, 1995). Science teachers are charged with the responsibility of incorporating both cognitive and non-cognitive parameters in their everyday teaching practices. This often results in their reluctance to teach science because they often lack disciplinary and/or pedagogical expertise required to promote science learning. The purpose of this study is to propose an alternative instructional approach in which Lego vehicles were used as a tool to promote pre-service elementary teachers' development and to examine whether there are non-cognitive parameters that promote or obstruct them from using Lego Technologies as a teaching tool. The context of the study was defined by a teacher preparation program of a private university in a small Mediterranean country. A sample of 28 pre-service elementary teachers, working in five 5-6-member groups were involved in scientific inquiries, during which they had to use vehicles in order to solve scientific problems related to concepts such as gear functioning, force, and motion. The nature of their cognitive engagement in the scientific inquiry process, non-cognitive parameters contributing to their cognitive engagement, and the impact of their involvement in the process on their development were examined through qualitative analysis of pre- and post-inquiry interviews, presentations of their solutions to the scientific problems and of their personal reflective journals.

Integrated learning of mathematics, science and technology concepts through LEGO/Logo projects

Science.gov (United States)

Wu, Lina

This dissertation examined integrated learning in the domains of mathematics, science and technology based on Piaget's constructivism, Papert's constructionism, and project-based approach to education. Ten fifth grade students were involved in a two-month long after school program where they designed and built their own computer-controlled LEGO/Logo projects that required the use of gears, ratios and motion concepts. The design of this study centered on three notions of integrated learning: (1) integration in terms of what educational materials/settings provide, (2) integration in terms of students' use of those materials, and (3) integration in the psychological sense. In terms of the first notion, the results generally showed that the LEGO/Logo environment supported the integrated learning of math, science and technology concepts. Regarding the second notion, the students all completed impressive projects of their own design. They successfully combined gears, motors, and LEGO parts together to create motion and writing control commands to manipulate the motion. But contrary to my initial expectations, their successful designs did not require numerical reasoning about ratios in designing effective gear systems. When they did reason about gear relationships, they worked with "qualitative" ratios, e.g., "a larger driver gear with a smaller driven gear increases the speed." In terms of the third notion of integrated learning, there was evidence in all four case study students of the psychological processes involved in linking mathematical, scientific, and/or technological concepts together to achieve new conceptual units. The students not only made connections between ideas and experiences, but also recognized decisive patterns and relationships in their project work. The students with stronger overall project performances showed more evidence of synthesis than the students with relatively weaker performances did. The findings support the conclusion that all three

Highly Manufacturable Deep (Sub-Millimeter) Etching Enabled High Aspect Ratio Complex Geometry Lego-Like Silicon Electronics

KAUST Repository

Ghoneim, Mohamed T.

2017-02-01

A highly manufacturable deep reactive ion etching based process involving a hybrid soft/hard mask process technology shows high aspect ratio complex geometry Lego-like silicon electronics formation enabling free-form (physically flexible, stretchable, and reconfigurable) electronic systems.

A Simple, Small-Scale Lego Colorimeter with a Light-Emitting Diode (LED) Used as Detector

Science.gov (United States)

Asheim, Jonas; Kvittingen, Eivind V.; Kvittingen, Lise; Verley, Richard

2014-01-01

This article describes how to construct a simple, inexpensive, and robust colorimeter from a few Lego bricks, in which one light-emitting diode (LED) is used as a light source and a second LED as a light detector. The colorimeter is suited to various grades and curricula.

A LEGO Watt balance: An apparatus to determine a mass based on the new SI

Science.gov (United States)

Chao, L. S.; Schlamminger, S.; Newell, D. B.; Pratt, J. R.; Seifert, F.; Zhang, X.; Sineriz, G.; Liu, M.; Haddad, D.

2015-11-01

A global effort to redefine our International System of Units (SI) is underway, and the change to the new system is expected to occur in 2018. Within the newly redefined SI, the present base units will still exist but be derived from fixed numerical values of seven reference constants. In particular, the unit of mass (the kilogram) will be realized through a fixed value of the Planck constant h. A so-called watt balance, for example, can then be used to realize the kilogram unit of mass within a few parts in 108. Such a balance has been designed and constructed at the National Institute of Standards and Technology. For educational outreach and to demonstrate the principle, we have constructed a LEGO tabletop watt balance capable of measuring a gram-level masses to 1% relative uncertainty. This article presents the design, construction, and performance of the LEGO watt balance and its ability to determine h.

The malleability of spatial ability under treatment of a FIRST LEGO League-based robotics unit

Science.gov (United States)

Coxon, Steven Vincent

Spatial ability is important to science, technology, engineering, and math (STEM) success, but spatial talents are rarely developed in schools. Likewise, the gifted may become STEM innovators, but they are rarely provided with pedagogy appropriate to develop their abilities in schools. A stratified random sample of volunteer participants (n=75) ages 9-14 was drawn from 16 public school districts' gifted programs, including as many females (n=28) and children from groups traditionally underrepresented in gifted programs (n=18) as available. Participants were randomly divided into an experimental (n=38) and a control group (n=37) for an intervention study. All participants took the CogAT (form 6) Verbal Battery and the Project TALENT Spatial Ability Assessments. The experimental group participated in a simulation of the FIRST LEGO League (FLL) competition for 20 hours total over five consecutive days. All participants took the spatial measure another time. Experimental males evidenced significant and meaningful gains in measured spatial ability (Cohen's d = 0.87). Females did not evidence significant gains in measured spatial ability. This may be due to sampling error, gender differences in prior experience with LEGO, or differences in facets of spatial ability in the treatment or measurements. Further research studies with larger samples of females, other treatments and measurement tools, and longer treatment periods are recommended. The literature review revealed that FLL is beneficial for STEM engagement in both genders and its use in schools is recommended. The present study provides additional evidence for FLL's usefulness in increasing the number of individuals in the STEM pipeline. Keywords: spatial, gilled, talent, robotics, FIRST LEGO League, science

Computing confidence and prediction intervals of industrial equipment degradation by bootstrapped support vector regression

International Nuclear Information System (INIS)

Lins, Isis Didier; Droguett, Enrique López; Moura, Márcio das Chagas; Zio, Enrico; Jacinto, Carlos Magno

2015-01-01

Data-driven learning methods for predicting the evolution of the degradation processes affecting equipment are becoming increasingly attractive in reliability and prognostics applications. Among these, we consider here Support Vector Regression (SVR), which has provided promising results in various applications. Nevertheless, the predictions provided by SVR are point estimates whereas in order to take better informed decisions, an uncertainty assessment should be also carried out. For this, we apply bootstrap to SVR so as to obtain confidence and prediction intervals, without having to make any assumption about probability distributions and with good performance even when only a small data set is available. The bootstrapped SVR is first verified on Monte Carlo experiments and then is applied to a real case study concerning the prediction of degradation of a component from the offshore oil industry. The results obtained indicate that the bootstrapped SVR is a promising tool for providing reliable point and interval estimates, which can inform maintenance-related decisions on degrading components. - Highlights: • Bootstrap (pairs/residuals) and SVR are used as an uncertainty analysis framework. • Numerical experiments are performed to assess accuracy and coverage properties. • More bootstrap replications does not significantly improve performance. • Degradation of equipment of offshore oil wells is estimated by bootstrapped SVR. • Estimates about the scale growth rate can support maintenance-related decisions

Basic concepts of automation and mechatronics with LEGO mindstorms NXT

Directory of Open Access Journals (Sweden)

Matijević Milan S.

2014-01-01

Full Text Available Mindstorsms LEGO NXT is using in engineering education at well recognized engineering schools like RWTH Aachen University where is created the RWTH - Mindstorms NXT Toolbox for Matlab. MATLAB / Simulink is widely available and popular for students around the world, but software toolboxes which are required for work with the real time systems are too expensive for the universities, especially those in developing countries. This paper describes an approach that is currently used in introductory subjects in the field of automation and mechatronics at the University of Kragujevac, and that does not require expensive software support.

Highly Manufacturable Deep (Sub-Millimeter) Etching Enabled High Aspect Ratio Complex Geometry Lego-Like Silicon Electronics.

Science.gov (United States)

Ghoneim, Mohamed Tarek; Hussain, Muhammad Mustafa

2017-04-01

A highly manufacturable deep reactive ion etching based process involving a hybrid soft/hard mask process technology shows high aspect ratio complex geometry Lego-like silicon electronics formation enabling free-form (physically flexible, stretchable, and reconfigurable) electronic systems. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

LEGO Mindstorms NXT for elderly and visually impaired people in need: A platform.

Science.gov (United States)

Al-Halhouli, Ala'aldeen; Qitouqa, Hala; Malkosh, Nancy; Shubbak, Alaa; Al-Gharabli, Samer; Hamad, Eyad

2016-07-27

This paper presents the employment of LEGO Mindstorms NXT robotics as core component of low cost multidisciplinary platform for assisting elderly and visually impaired people. LEGO Mindstorms system offers a plug-and-play programmable robotics toolkit, incorporating construction guides, microcontrollers and sensors, all connected via a comprehensive programming language. It facilitates, without special training and at low cost, the use of such device for interpersonal communication and for handling multiple tasks required for elderly and visually impaired people in-need. The research project provides a model for larger-scale implementation, tackling the issues of creating additional functions in order to assist people in-need. The new functions were built and programmed using MATLAB through a user friendly Graphical User Interface (GUI). Power consumption problem, besides the integration of WiFi connection has been resolved, incorporating GPS application on smart phones enhanced the guiding and tracking functions. We believe that developing and expanding the system to encompass a range of applications beyond the initial design schematics to ease conducting a limited number of pre-described protocols. However, the beneficiaries for the proposed research would be limited to elderly people who require assistance within their household as assistive-robot to facilitate a low-cost solution for a highly demanding health circumstance.

Protein Assembly and Building Blocks: Beyond the Limits of the LEGO Brick Metaphor.

Science.gov (United States)

Levy, Yaakov

2017-09-26

Proteins, like other biomolecules, have a modular and hierarchical structure. Various building blocks are used to construct proteins of high structural complexity and diverse functionality. In multidomain proteins, for example, domains are fused to each other in different combinations to achieve different functions. Although the LEGO brick metaphor is justified as a means of simplifying the complexity of three-dimensional protein structures, several fundamental properties (such as allostery or the induced-fit mechanism) make deviation from it necessary to respect the plasticity, softness, and cross-talk that are essential to protein function. In this work, we illustrate recently reported protein behavior in multidomain proteins that deviates from the LEGO brick analogy. While earlier studies showed that a protein domain is often unaffected by being fused to another domain or becomes more stable following the formation of a new interface between the tethered domains, destabilization due to tethering has been reported for several systems. We illustrate that tethering may sometimes result in a multidomain protein behaving as "less than the sum of its parts". We survey these cases for which structure additivity does not guarantee thermodynamic additivity. Protein destabilization due to fusion to other domains may be linked in some cases to biological function and should be taken into account when designing large assemblies.

A model of Altio Lazio boiling water reactor using the LEGO code nuclear steam supply system simulation

International Nuclear Information System (INIS)

Garbossa, G.B.; Spelta, S.; Cori, R.; Mosca, R.; Cento, P.

1989-01-01

An extensive effort has been made at the Italian National Electricity Board (ENEL) to construct and validate a LEGO model capable of simulating the operational transients of the Alto Lazio Nuclear Station, a two-twin units site with BWR/6 class reactors, rated at 2894 MWt and with Mark III containment. The desired end-product of this effort is an overall plant model consisting of the Nuclear Steam Supply System model, described in this paper, and the Balance of Plant model, capable of simulating the transient response of Alto Lazio Station. The models utilize the in-house developed LEGO code, which is a modular package oriented to power plant modeling and suitable to perform transient analyses to assist during power plant design, control system design and operating procedure verification. The ability of the NSSS model to predict correctly the plant response is demonstrated through comparison with results calculated by the vendor, using REDY code, and by an in-house RETRAN-02 model

The Effects of Integrating LEGO Robotics into a Mathematics Curriculum to Promote the Development of Proportional Reasoning

Science.gov (United States)

Casler-Failing, Shelli L.

2017-01-01

This mixed methods, action research case study sought to investigate the effects of incorporating LEGO robotics into a seventh grade mathematics curriculum focused on the development of proportional reasoning through the lens of Social Constructivist Theory. Quantitative data was collected via pre- and post-tests from the mathematics class of six…

Using Lego robots to estimate cognitive ability in children who have severe physical disabilities.

Science.gov (United States)

Cook, Albert M; Adams, Kim; Volden, Joanne; Harbottle, Norma; Harbottle, Cheryl

2011-01-01

To determine whether low-cost robots provide a means by which children with severe disabilities can demonstrate understanding of cognitive concepts. Ten children, ages 4 to 10, diagnosed with cerebral palsy and related motor conditions, participated. Participants had widely variable motor, cognitive and receptive language skills, but all were non-speaking. A Lego Invention 'roverbot' was used to carry out a range of functional tasks from single-switch replay of pre-stored movements to total control of the movement in two dimensions. The level of sophistication achieved on hierarchically arranged play tasks was used to estimate cognitive skills. The 10 children performed at one of the six hierarchically arranged levels from 'no interaction' through 'simple cause and effect' to 'development and execution of a plan'. Teacher interviews revealed that children were interested in the robot, enjoyed interacting with it and demonstrated changes in behaviour and social and language skills following interaction. Children with severe physical disabilities can control a Lego robot to perform un-structured play tasks. In some cases, they were able to display more sophisticated cognitive skills through manipulating the robot than in traditional standardised tests. Success with the robot could be a proxy measure for children who have cognitive abilities but cannot demonstrate them in standard testing.

Culture’s building blocks: Investigating cultural evolution in a LEGO construction task

DEFF Research Database (Denmark)

McGraw, John J.; Wallot, Sebastian; Mitkidis, Panagiotis

2014-01-01

to culture remains little more than a suggestive trope. Whereas the modern synthesis of evolutionary theory has provided an encompassing scientific framework for the selection and transmission of biological adaptations, a convincing theory of cultural evolution has yet to emerge. One of the greatest...... the ways people develop conventions in a series of LEGO construction tasks. The data revealed a surprising pattern in the selection of building bricks as well as features of car design across consecutive building sessions. Our findings support a novel methodology for studying the development...

Investigation of Self-assembly Structure and Properties of a Novel Designed Lego-type Peptide with Double Amphiphilic Surfaces

Energy Technology Data Exchange (ETDEWEB)

Wang, Liang [Sichuan University, Sichuan (China); Zhao, Xiao Jun [Massachusetts Institute of Technology, Cambridge (United States)

2010-12-15

A typically designed 'Peptide Lego' has two distinct surfaces: a hydrophilic side that contains the complete charge distribution and a hydrophobic side. In this article, we describe the fabrication of a unique lego-type peptide with the AEAEYAKAK sequence. The novel peptide with double amphiphilic surfaces is different from typical peptides due to special arrangement of the residues. The results of CD, FT-IR, AFM and DLS demonstrate that the peptide with the random coil characteristic was able to form stable nanostructures that were mediated by non-covalent interactions in an aqueous solution. The data further indicated that despite its different structure, the peptide was able to undergo self-assembly similar to a typical peptide. In addition, the use of hydrophobic pyrene as a model allowed the peptide to provide a new type of potential nanomaterial for drug delivery. These efforts collectively open up a new direction in the fabrication of nanomaterials that are more perfect and versatile.

Investigation of Self-assembly Structure and Properties of a Novel Designed Lego-type Peptide with Double Amphiphilic Surfaces

International Nuclear Information System (INIS)

Wang, Liang; Zhao, Xiao Jun

2010-01-01

A typically designed 'Peptide Lego' has two distinct surfaces: a hydrophilic side that contains the complete charge distribution and a hydrophobic side. In this article, we describe the fabrication of a unique lego-type peptide with the AEAEYAKAK sequence. The novel peptide with double amphiphilic surfaces is different from typical peptides due to special arrangement of the residues. The results of CD, FT-IR, AFM and DLS demonstrate that the peptide with the random coil characteristic was able to form stable nanostructures that were mediated by non-covalent interactions in an aqueous solution. The data further indicated that despite its different structure, the peptide was able to undergo self-assembly similar to a typical peptide. In addition, the use of hydrophobic pyrene as a model allowed the peptide to provide a new type of potential nanomaterial for drug delivery. These efforts collectively open up a new direction in the fabrication of nanomaterials that are more perfect and versatile

How the LEGO Group Is Embarking on Architectural Path Constitution to Transform Its Information Infrastructure into a Digital Platform

DEFF Research Database (Denmark)

Törmer, Robert Lorenz

2018-01-01

Traditional companies are increasingly turning towards platform strategies to gain speed in the development of digital value propositions and prepare for the challenges arising from digitalization. This paper reports on the digitalization journey of the LEGO Group to elaborate how brick-and-mortar...

High School Students' Views on the PBL Activities Supported via Flipped Classroom and LEGO Practices

Science.gov (United States)

Cukurbasi, Baris; Kiyici, Mubin

2018-01-01

The purpose of this study was to investigate the high school students' views on instructions based on Flipped Classroom Model (FC) and LEGO applications. The case study, which is one of the qualitative research methods, was used within the scope of the study, the duration of which was 7 weeks. In order to choose the research group of the study,…

Facilities Management and Value Adding - The LEGO case

DEFF Research Database (Denmark)

Jensen, Per Anker; Katchamart, Akarapong

on the management model for FM included in the European FM standards, recent theories on added value of FM and real estate and the related concept of Value Management from building projects. The paper outlines a preliminary theoretical based management concept, which is investigated, tested and discussed based...... on a case study of LEGO. Results: The study shows that the management model for FM creates a relevant starting point but also that stakeholder and relationship management is an essential aspect of Value Adding Management. The case study confirms the relevance of the basic concept and provides an important...... example of how Value Adding Management can be implemented and added value measured. Practical Implications: The concept of Value Adding Management is expected to increase the awareness of the impacts and strategic importance of FM for organisations and can be a practical tool for facilities managers...

The Effect on Pupils' Science Performance and Problem-Solving Ability through Lego: An Engineering Design-Based Modeling Approach

Science.gov (United States)

Li, Yanyan; Huang, Zhinan; Jiang, Menglu; Chang, Ting-Wen

2016-01-01

Incorporating scientific fundamentals via engineering through a design-based methodology has proven to be highly effective for STEM education. Engineering design can be instantiated for learning as they involve mental and physical stimulation and develop practical skills especially in solving problems. Lego bricks, as a set of toys based on design…

Using Python to Program LEGO MINDSTORMS® Robots: The PyNXC Project

Directory of Open Access Journals (Sweden)

2010-04-01

Full Text Available

 

Localization of thermal anomalies in electrical equipment using Infrared Thermography and support vector machine

Science.gov (United States)

Laib dit Leksir, Y.; Mansour, M.; Moussaoui, A.

2018-03-01

Analysis and processing of databases obtained from infrared thermal inspections made on electrical installations require the development of new tools to obtain more information to visual inspections. Consequently, methods based on the capture of thermal images show a great potential and are increasingly employed in this field. However, there is a need for the development of effective techniques to analyse these databases in order to extract significant information relating to the state of the infrastructures. This paper presents a technique explaining how this approach can be implemented and proposes a system that can help to detect faults in thermal images of electrical installations. The proposed method classifies and identifies the region of interest (ROI). The identification is conducted using support vector machine (SVM) algorithm. The aim here is to capture the faults that exist in electrical equipments during an inspection of some machines using A40 FLIR camera. After that, binarization techniques are employed to select the region of interest. Later the comparative analysis of the obtained misclassification errors using the proposed method with Fuzzy c means and Ostu, has also be addressed.

3D printed Lego®-like modular microfluidic devices based on capillary driving.

Science.gov (United States)

Nie, Jing; Gao, Qing; Qiu, Jing-Jiang; Sun, Miao; Liu, An; Shao, Lei; Fu, Jian-Zhong; Zhao, Peng; He, Yong

2018-03-12

The field of how to rapidly assemble microfluidics with modular components continuously attracts researchers' attention, however, extra efforts must be devoted to solving the problems of leaking and aligning between individual modules. This paper presents a novel type of modular microfluidic device, driven by capillary force. There is no necessity for a strict seal or special alignment, and its open structures make it easy to integrate various stents and reactants. The key rationale for this method is to print different functional modules with a low-cost three-dimensional (3D) printer, then fill the channels with capillary materials and assemble them with plugs like Lego ® bricks. This rapidly reconstructed modular microfluidic device consists of a variety of common functional modules and other personalized modules, each module having a unified standard interface for easy assembly. As it can be printed by a desktop 3D printer, the manufacturing process is simple and efficient, with controllable regulation of the flow channel scale. Through diverse combinations of different modules, a variety of different functions can be achieved, without duplicating the manufacturing process. A single module can also be taken out for testing and analysis. What's more, combined with basic circuit components, it can serve as a low-cost Lego ® -like modular microfluidic circuits. As a proof of concept, the modular microfluidic device has been successfully demonstrated and used for stent degradation and cell cultures, revealing the potential use of this method in both chemical and biological research.

Mechatronics Education: From Paper Design to Product Prototype Using LEGO NXT Parts

Science.gov (United States)

Lofaro, Daniel M.; Le, Tony Truong Giang; Oh, Paul

The industrial design cycle starts with design then simulation, prototyping, and testing. When the tests do not match the design requirements the design process is started over again. It is important for students to experience this process before they leave their academic institution. The high cost of the prototype phase, due to CNC/Rapid Prototype machine costs, makes hands on study of this process expensive for students and the academic institutions. This document shows that the commercially available LEGO NXT Robot kit is a viable low cost surrogate to the expensive industrial CNC/Rapid Prototype portion of the industrial design cycle.

Building a Lego wall: Sequential action selection.

Science.gov (United States)

Arnold, Amy; Wing, Alan M; Rotshtein, Pia

2017-05-01

The present study draws together two distinct lines of enquiry into the selection and control of sequential action: motor sequence production and action selection in everyday tasks. Participants were asked to build 2 different Lego walls. The walls were designed to have hierarchical structures with shared and dissociated colors and spatial components. Participants built 1 wall at a time, under low and high load cognitive states. Selection times for correctly completed trials were measured using 3-dimensional motion tracking. The paradigm enabled precise measurement of the timing of actions, while using real objects to create an end product. The experiment demonstrated that action selection was slowed at decision boundary points, relative to boundaries where no between-wall decision was required. Decision points also affected selection time prior to the actual selection window. Dual-task conditions increased selection errors. Errors mostly occurred at boundaries between chunks and especially when these required decisions. The data support hierarchical control of sequenced behavior. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The Effect of LEGO Training on Pupils' School Performance in Mathematics, Problem Solving Ability and Attitude: Swedish Data

Science.gov (United States)

Hussain, Shakir; Lindh, Jorgen; Shukur, Ghazi

2006-01-01

The purpose of this study is to investigate the effect of one year of regular "LEGO" training on pupils' performances in schools. The underlying pedagogical perspective is the constructivist theory, where the main idea is that knowledge is constructed in the mind of the pupil by active learning. The investigation has been made in two…

Fictions industrielles et apprentissage du temps : les jeux LEGO Bionicles

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Irène Langlet

2011-06-01

Full Text Available Il y a un paradoxe LEGO : venue tard aux nouveaux jouets médiatiques et numériques, la firme danoise a pourtant lancé l’un des phénomènes les plus exemplaires des années 2000 : la gamme Bionicle, qui mêle figurines, jeux de construction, fictions populaires multi-supports (imprimé, télévision, jeux vidéo, CD-Rom, cinéma, communautés de joueurs sur internet, univers partagé, et tous les produits non ludiques dérivés. Une description fine de la gamme Bionicle fait apparaître d’emblée, non seulement son adéquation étroite aux problématiques de porosité intermédiatique et d’exploitation de la fiction, mais son innovation majeure, étroitement liée à la nature des produits de la firme LEGO. Dans un processus de « médiatisation », la gamme accomplit, après la généralisation de séries thématiques favorisant l’imaginaire, le passage de LEGO à la narrativisation. On montrera en quoi l’introduction du narratif dans cette gamme a répondu à cet objectif-maître de l’industrie des biens de consommation en régime médiatique : consommer du média, c’est encore jouer au jeu-noyau. Mais on verra aussi en quoi ce cadre narratif peut suggérer des analyses qui vont au-delà de la théorie du marketing ou de la didactique du jouet, et qui ont trait aux usages contemporains de la fiction et à la psychologie du développement en matière de maîtrise de la temporalité.

A LEGO Mindstorms NXT Approach for Teaching at Data Acquisition, Control Systems Engineering and Real-Time Systems Undergraduate Courses

Science.gov (United States)

Cruz-Martin, A.; Fernandez-Madrigal, J. A.; Galindo, C.; Gonzalez-Jimenez, J.; Stockmans-Daou, C.; Blanco-Claraco, J. L.

2012-01-01

LEGO Mindstorms NXT robots are being increasingly used in undergraduate courses, mostly in robotics-related subjects. But other engineering topics, like the ones found in data acquisition, control and real-time subjects, also have difficult concepts that can be well understood only with good lab exercises. Such exercises require physical…

Examining Students' Proportional Reasoning Strategy Levels as Evidence of the Impact of an Integrated LEGO Robotics and Mathematics Learning Experience

Science.gov (United States)

Martínez Ortiz, Araceli

2015-01-01

The presented study used a problem-solving experience in engineering design with LEGO robotics materials as the real-world mathematics-learning context. The goals of the study were (a) to determine if a short but intensive extracurricular learning experience would lead to significant student learning of a particular academic topic and (b) to…

Motivating programming students by Problem Based Learning and LEGO robots

DEFF Research Database (Denmark)

Lykke, Marianne; Coto Chotto, Mayela; Mora, Sonia

2014-01-01

. For this reason the school is focusing on different teaching methods to help their students master these skills. This paper introduces an experimental, controlled comparison study of three learning designs, involving a problem based learning (PBL) approach in connection with the use of LEGO Mindstorms to improve...... students programming skills and motivation for learning in an introductory programming course. The paper reports the results related with one of the components of the study - the experiential qualities of the three learning designs. The data were collected through a questionnaire survey with 229 students...... from three groups exposed to different learning designs and through six qualitative walk-alongs collecting data from these groups by informal interviews and observations. Findings from the three studies were discussed in three focus group interviews with 10 students from the three experimental groups....

LEGO Mindstorms NXT: Juego como Herramienta de Aprendizaje de Programación

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Leidy Diana Jiménez-Pinzón

2014-06-01

Full Text Available LEGO Mindstorms es un juego que se usa como herramienta para el aprendizaje de distintas áreas de conocimiento. Una persona puede aprender acerca de programación mediante distintos lenguajes y aplicaciones para compilar el código de la solución planteada y resolver una situación particular. Sin embargo, la enseñanza de programación es sólo un fundamento teórico y poco práctico. Por estas razones, se pretende enseñar a programar mediante un lenguaje sencillo y una plataforma que permita visualizar el código gráficamente y validarlo específicamente con las instrucciones programadas sobre un robot.

Modelamiento y programación de un juego de legos en un entorno de realidad virtual

OpenAIRE

Arboleda, Freddy; Laica, Ricardo; Loor, Magdalena; García, Sixto

2011-01-01

This project seeks by the use of the techn Lego blocks, in order to check the applicability of the concepts learned throughout the topic specifies the general ideas on the model blocks. First, we focus in the creation of the 3D objects and scenes, which are going to constitute the virtual environment. Later, we are going to detail the different positioning and control algorithms created to help us in the precision and the logic en the movements of the virtu and disadvantages...

A LEGO paradigm for virtual accelerator concept

International Nuclear Information System (INIS)

Andrianov, S.; Ivanov, A.; Podzyvalov, E.

2012-01-01

The paper considers basic features of a Virtual Accelerator concept based on LEGO paradigm. This concept involves three types of components: different mathematical models for accelerator design problems, integrated beam simulation packages (i. e. COSY, MAD, OptiM and others), and a special class of virtual feedback instruments similar to real control systems (EPICS). All of these components should inter-operate for more complete analysis of control systems and increased fault tolerance. The Virtual Accelerator is an information and computing environment which provides a framework for analysis based on these components that can be combined in different ways. Corresponding distributed computing services establish interaction between mathematical models and low level control system. The general idea of the software implementation is based on the Service-Oriented Architecture (SOA) that allows using cloud computing technology and enables remote access to the information and computing resources. The Virtual Accelerator allows a designer to combine powerful instruments for modeling beam dynamics in a friendly way including both self-developed and well-known packages. In the scope of this concept the following is also proposed: the control system identification, analysis and result verification, visualization as well as virtual feedback for beam line operation. The architecture of the Virtual Accelerator system itself and results of beam dynamics studies are presented. (authors)

Using FIRST LEGO League Robotics Competitions to Engage Middle School Students in Physics

Science.gov (United States)

Rosen, Jeffrey

2009-11-01

As the nation and world grapple with looming crises in sectors such as energy, health care and the environment, it is critical that we keep today's youth interested in careers in science, technology, engineering and math (STEM). Studies indicate that many students lose interest in the sciences by ages 10-13, when they are in grades 4-8 in the U.S. educational system. Many of the interventions to counteract this trend focus on boosting interest in STEM in secondary schools and universities. However the case can be made that the greater need is actually earlier in the education of the child. How can we work with this age group in an exciting way that will promote the study of science? Student robotics competitions might be one effective answer. Programs are currently being run around the country and the world that engage young people in the study of science through robotic competition. Many of these programs rely on mentors to guide the students through the process, which in the most effective programs includes the study of physic concepts through engineering design. During this presentation we will discuss the options for participating in programs that help the students and teachers better understand the science, specifically the physics, which underlies robotics. In particular, we will focus on the international program called FIRST LEGO League (FLL), in which students ages 9-14 are challenged every year to construct a LEGO robot that can navigate and complete a course of theme-related missions. The FLL program is currently operating in almost every state in the U.S. and relies on recruiting qualified mentors and judges who want to impact young people's interest in STEM. Physics professionals can make a tremendous difference in the lives of these eager middle school students.

Multiplexing clonality: combining RGB marking and genetic barcoding

Science.gov (United States)

Cornils, Kerstin; Thielecke, Lars; Hüser, Svenja; Forgber, Michael; Thomaschewski, Michael; Kleist, Nadja; Hussein, Kais; Riecken, Kristoffer; Volz, Tassilo; Gerdes, Sebastian; Glauche, Ingmar; Dahl, Andreas; Dandri, Maura; Roeder, Ingo; Fehse, Boris

2014-01-01

RGB marking and DNA barcoding are two cutting-edge technologies in the field of clonal cell marking. To combine the virtues of both approaches, we equipped LeGO vectors encoding red, green or blue fluorescent proteins with complex DNA barcodes carrying color-specific signatures. For these vectors, we generated highly complex plasmid libraries that were used for the production of barcoded lentiviral vector particles. In proof-of-principle experiments, we used barcoded vectors for RGB marking of cell lines and primary murine hepatocytes. We applied single-cell polymerase chain reaction to decipher barcode signatures of individual RGB-marked cells expressing defined color hues. This enabled us to prove clonal identity of cells with one and the same RGB color. Also, we made use of barcoded vectors to investigate clonal development of leukemia induced by ectopic oncogene expression in murine hematopoietic cells. In conclusion, by combining RGB marking and DNA barcoding, we have established a novel technique for the unambiguous genetic marking of individual cells in the context of normal regeneration as well as malignant outgrowth. Moreover, the introduction of color-specific signatures in barcodes will facilitate studies on the impact of different variables (e.g. vector type, transgenes, culture conditions) in the context of competitive repopulation studies. PMID:24476916

A Test Platform for Planned Field Operations Using LEGO Mindstorms NXT

Directory of Open Access Journals (Sweden)

Gareth Edwards

2013-11-01

Full Text Available Testing agricultural operations and management practices associated with different machinery, systems and planning approaches can be both costly and time-consuming. Computer simulations of such systems are used for development and testing; however, to gain the experience of real-world performance, an intermediate step between simulation and full-scale testing should be included. In this paper, a potential common framework using the LEGO Mindstorms NXT micro-tractor platform is described in terms of its hardware and software components. The performance of the platform is demonstrated and tested in terms of its capability of supporting decision making on infield operation planning. The proposed system represents the basic measures for developing a complete test platform for field operations, where route plans, mission plans, multiple-machinery cooperation strategies and machinery coordination can be executed and tested in the laboratory.

Improving collaborative play between children with autism spectrum disorders and their siblings : the effectiveness of a robot-mediated intervention based on lego (R) therapy

NARCIS (Netherlands)

Huskens, Bibi; Palmen, Annemiek; Van der Werff, Marije; Lourens, Tino; Barakova, Emilia

2015-01-01

The aim of the study was to investigate the effectiveness of a brief robot-mediated intervention based on Lego(A (R)) therapy on improving collaborative behaviors (i.e., interaction initiations, responses, and play together) between children with ASD and their siblings during play sessions, in a

ESTUDIO Y MODELADO DE UN BRAZO ROBÓTICO LEGO DE TRES GRADOS DE LIBERTAD

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JAIME ALBERTO GUZMÁN

2011-12-01

Full Text Available En este artículo se presenta el estudio y modelado de un brazo robótico lego de tres grados de libertad en asocio con sus respectivos modelos de su cinemática directa e inversa junto con una aproximación al análisis dinámico para la generación de trayectorias de este robot. Las ecuaciones que rigen el movimiento son deducidas de los modelos matemáticos propios a las cadenas cinemáticas y son implementadas en el lenguaje de programación Java y ejecutadas por el robot a través de la extensión Java -LeJOS.

Determining suitable lego-structures to estimate stability of larger peptide nanostructures using computational methods.

Science.gov (United States)

Beke, Tamás; Czajlik, András; Csizmadia, Imre G; Perczel, András

2006-02-02

Nanofibers, nanofilms and nanotubes constructed of one to four strands of oligo-alpha- and oligo-beta-peptides were obtained by using carefully selected building units. Lego-type approaches based on thermoneutral isodesmic reactions can be used to reconstruct the total energies of both linear and tubular periodic nanostructures with acceptable accuracy. Total energies of several different nanostructures were accurately determined with errors typically falling in the subchemical range. Thus, attention will be focused on the description of suitable isodesmic reactions that have enabled the determination of the total energy of polypeptides and therefore offer a very fast, efficient and accurate method to obtain energetic information on large and even very large nanosystems.

Lego Robots & Autism Spectrum Disorder: a potential partnership?

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Sandra Costa

2016-06-01

Full Text Available Individuals with autism spectrum disorder (ASD present difficulties in developing social behaviours, in communicating gestural or verbally, and they may present some repetitive motor activities. The objective of this study was to improve social competences and to enable the transfer of acquired skills of five children with ASD and intellectual disabilities using a low-cost Lego robot as a mediator. The proposed methodology was divided in five phases: Familiarization, Pre-test, Practice, Post-Test and Transfer of Skills. The study ran in two sequential periods at different places. Each of these periods tackled different individual research questions and goals (taking into account the target group. During each period, the proposed methodology had to be adjusted according to the current context. Therefore, different experimental scenarios and corresponding specific goals had to be delineated. Results show that joint attention of the children increased over the sessions; and interaction with the researcher was verified. Furthermore, results show that there was an effective transfer of skills in the addressed case studies. This reinforces conclusions that robots seem, in fact, powerful tools that should be explored concerning this target population. But a more detailed study is required. The proposed methodology can be used by professionals and parents as a complement to common interventions.

Improving Collaborative Play between Children with Autism Spectrum Disorders and Their Siblings: The Effectiveness of a Robot-Mediated Intervention Based on Lego® Therapy

Science.gov (United States)

Huskens, Bibi; Palmen, Annemiek; Van der Werff, Marije; Lourens, Tino; Barakova, Emilia

2015-01-01

The aim of the study was to investigate the effectiveness of a brief robot-mediated intervention based on Lego® therapy on improving collaborative behaviors (i.e., interaction initiations, responses, and play together) between children with ASD and their siblings during play sessions, in a therapeutic setting. A concurrent multiple baseline design…

Great Ellipse Route Planning Based on Space Vector

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LIU Wenchao

2015-07-01

Full Text Available Aiming at the problem of navigation error caused by unified earth model in great circle route planning using sphere model and modern navigation equipment using ellipsoid mode, a method of great ellipse route planning based on space vector is studied. By using space vector algebra method, the vertex of great ellipse is solved directly, and description of great ellipse based on major-axis vector and minor-axis vector is presented. Then calculation formulas of great ellipse azimuth and distance are deduced using two basic vectors. Finally, algorithms of great ellipse route planning are studied, especially equal distance route planning algorithm based on Newton-Raphson(N-R method. Comparative examples show that the difference of route planning between great circle and great ellipse is significant, using algorithms of great ellipse route planning can eliminate the navigation error caused by the great circle route planning, and effectively improve the accuracy of navigation calculation.

LEGO-NMR spectroscopy: a method to visualize individual subunits in large heteromeric complexes.

Science.gov (United States)

Mund, Markus; Overbeck, Jan H; Ullmann, Janina; Sprangers, Remco

2013-10-18

Seeing the big picture: Asymmetric macromolecular complexes that are NMR active in only a subset of their subunits can be prepared, thus decreasing NMR spectral complexity. For the hetero heptameric LSm1-7 and LSm2-8 rings NMR spectra of the individual subunits of the complete complex are obtained, showing a conserved RNA binding site. This LEGO-NMR technique makes large asymmetric complexes accessible to detailed NMR spectroscopic studies. © 2013 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of Creative Commons the Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Structural insight into RNA recognition motifs: versatile molecular Lego building blocks for biological systems.

Science.gov (United States)

Muto, Yutaka; Yokoyama, Shigeyuki

2012-01-01

'RNA recognition motifs (RRMs)' are common domain-folds composed of 80-90 amino-acid residues in eukaryotes, and have been identified in many cellular proteins. At first they were known as RNA binding domains. Through discoveries over the past 20 years, however, the RRMs have been shown to exhibit versatile molecular recognition activities and to behave as molecular Lego building blocks to construct biological systems. Novel RNA/protein recognition modes by RRMs are being identified, and more information about the molecular recognition by RRMs is becoming available. These RNA/protein recognition modes are strongly correlated with their biological significance. In this review, we would like to survey the recent progress on these versatile molecular recognition modules. Copyright © 2012 John Wiley & Sons, Ltd.

A Lego Mindstorms NXT based test bench for multiagent exploratory systems and distributed network partitioning

Science.gov (United States)

Patil, Riya Raghuvir

Networks of communicating agents require distributed algorithms for a variety of tasks in the field of network analysis and control. For applications such as swarms of autonomous vehicles, ad hoc and wireless sensor networks, and such military and civilian applications as exploring and patrolling a robust autonomous system that uses a distributed algorithm for selfpartitioning can be significantly helpful. A single team of autonomous vehicles in a field may need to self-dissemble into multiple teams, conducive to completing multiple control tasks. Moreover, because communicating agents are subject to changes, namely, addition or failure of an agent or link, a distributed or decentralized algorithm is favorable over having a central agent. A framework to help with the study of self-partitioning of such multi agent systems that have most basic mobility model not only saves our time in conception but also gives us a cost effective prototype without negotiating the physical realization of the proposed idea. In this thesis I present my work on the implementation of a flexible and distributed stochastic partitioning algorithm on the LegoRTM Mindstorms' NXT on a graphical programming platform using National Instruments' LabVIEW(TM) forming a team of communicating agents via NXT-Bee radio module. We single out mobility, communication and self-partition as the core elements of the work. The goal is to randomly explore a precinct for reference sites. Agents who have discovered the reference sites announce their target acquisition to form a network formed based upon the distance of each agent with the other wherein the self-partitioning begins to find an optimal partition. Further, to illustrate the work, an experimental test-bench of five Lego NXT robots is presented.

Dorello's Canal for Laymen: A Lego-Like Presentation.

Science.gov (United States)

Ezer, Haim; Banerjee, Anirban Deep; Thakur, Jai Deep; Nanda, Anil

2012-06-01

Objective Dorello's canal was first described by Gruber in 1859, and later by Dorello. Vail also described the anatomy of Dorello's canal. In the preceding century, Dorello's canal was clinically important, in understanding sixth nerve palsy and nowadays it is mostly important for skull base surgery. The understanding of the three dimensional anatomy, of this canal is very difficult to understand, and there is no simple explanation for its anatomy and its relationship with adjacent structures. We present a simple, Lego-like, presentation of Dorello's canal, in a stepwise manner. Materials and Methods Dorello's canal was dissected in five formalin-fixed cadaver specimens (10 sides). The craniotomy was performed, while preserving the neural and vascular structures associated with the canal. A 3D model was created, to explain the canal's anatomy. Results Using the petrous pyramid, the sixth nerve, the cavernous sinus, the trigeminal ganglion, the petorclival ligament and the posterior clinoid, the three-dimensional structure of Dorello's canal was defined. This simple representation aids in understanding the three dimensional relationship of Dorello's canal to its neighboring structures. Conclusion Dorello's canal with its three dimensional structure and relationship to its neighboring anatomical structures could be reconstructed using a few anatomical building blocks. This method simplifies the understanding of this complex anatomical structure, and could be used for teaching purposes for aspiring neurosurgeons, and anatomy students.

The Effect of Scratch- and Lego Mindstorms Ev3-Based Programming Activities on Academic Achievement, Problem-Solving Skills and Logical-Mathematical Thinking Skills of Students

Science.gov (United States)

Korkmaz, Özgen

2016-01-01

The aim of this study was to investigate the effect of the Scratch and Lego Mindstorms Ev3 programming activities on academic achievement with respect to computer programming, and on the problem-solving and logical-mathematical thinking skills of students. This study was a semi-experimental, pretest-posttest study with two experimental groups and…

Manipulating waves with LEGO{sup ®} bricks: A versatile experimental platform for metamaterial architectures

Energy Technology Data Exchange (ETDEWEB)

Celli, Paolo, E-mail: pcelli@umn.edu; Gonella, Stefano, E-mail: sgonella@umn.edu [Department of Civil, Environmental, and Geo- Engineering, University of Minnesota, Minneapolis, Minnesota 55455 (United States)

2015-08-24

In this letter, we discuss a versatile, fully reconfigurable experimental platform for the investigation of phononic phenomena in metamaterial architectures. The approach revolves around the use of 3D laser vibrometry to reconstruct global and local wavefield features in specimens obtained through simple arrangements of LEGO{sup ®} bricks on a thin baseplate. The agility by which it is possible to reconfigure the brick patterns into a nearly endless spectrum of topologies makes this an effective approach for rapid experimental proof of concept, as well as a powerful didactic tool, in the arena of phononic crystals and metamaterials engineering. We use our platform to provide a compelling visual illustration of important spatial wave manipulation effects (waveguiding and seismic isolation), and to elucidate fundamental dichotomies between Bragg-based and locally resonant bandgap mechanisms.

An introduction to vectors, vector operators and vector analysis

CERN Document Server

Joag, Pramod S

2016-01-01

Ideal for undergraduate and graduate students of science and engineering, this book covers fundamental concepts of vectors and their applications in a single volume. The first unit deals with basic formulation, both conceptual and theoretical. It discusses applications of algebraic operations, Levi-Civita notation, and curvilinear coordinate systems like spherical polar and parabolic systems and structures, and analytical geometry of curves and surfaces. The second unit delves into the algebra of operators and their types and also explains the equivalence between the algebra of vector operators and the algebra of matrices. Formulation of eigen vectors and eigen values of a linear vector operator are elaborated using vector algebra. The third unit deals with vector analysis, discussing vector valued functions of a scalar variable and functions of vector argument (both scalar valued and vector valued), thus covering both the scalar vector fields and vector integration.

Not Your Typical Simulation Workshop: Using LEGOs to Train Medical Students on the Practice of Effective Communication.

Science.gov (United States)

Papanagnou, Dimitrios; Lee, Hyunjoo; Rodriguez, Carlos; Zhang, Xiao Chi C; Rudner, Joshua

2018-01-21

As students in the health professions transition from the classroom into the clinical environment, they will be expected to effectively communicate with their team members and their patients. Effective communication skills are essential to their ability to effectively contribute to their clinical team and the patient care they deliver. The authors propose an interactive workshop that can support students' deliberate practice of communication skills. The authors designed a simulation workshop that affords students the opportunity to practice their communication and peer-to-peer coaching skills. Using LEGOs, a one-hour workshop was conducted with medical students. Students were divided into groups of two. Each student took on a different role: teacher or builder. Teachers were tasked with instructing builders on how to construct a pre-made LEGO structure, not allowing builders to look at the structure. A group debriefing followed to evaluate the activity and explore the themes that emerged. Twenty first-year medical students and 25 fourth-year medical students participated in this activity. Most groups were successful in reproducing the pre-made structure. Groups that pre-briefed before building were most successful. Unsuccessful groups did not define orientation or direction in mutually understood terms, resulting in the creation of an incorrect mirror image of the structure - a common phenomenon seen during the teaching of procedures in the clinical learning environment. The workshop was well received. Students made requests to have similar sessions throughout their training to better support the development of effective communication skills. The workshop can easily be applied to other specialties to assist with procedural skills instruction or in workshops focusing on effective communication.

Not Your Typical Simulation Workshop: Using LEGOs to Train Medical Students on the Practice of Effective Communication

Science.gov (United States)

Lee, Hyunjoo; Rodriguez, Carlos; Zhang, Xiao Chi C; Rudner, Joshua

2018-01-01

As students in the health professions transition from the classroom into the clinical environment, they will be expected to effectively communicate with their team members and their patients. Effective communication skills are essential to their ability to effectively contribute to their clinical team and the patient care they deliver. The authors propose an interactive workshop that can support students’ deliberate practice of communication skills. The authors designed a simulation workshop that affords students the opportunity to practice their communication and peer-to-peer coaching skills. Using LEGOs, a one-hour workshop was conducted with medical students. Students were divided into groups of two. Each student took on a different role: teacher or builder. Teachers were tasked with instructing builders on how to construct a pre-made LEGO structure, not allowing builders to look at the structure. A group debriefing followed to evaluate the activity and explore the themes that emerged. Twenty first-year medical students and 25 fourth-year medical students participated in this activity. Most groups were successful in reproducing the pre-made structure. Groups that pre-briefed before building were most successful. Unsuccessful groups did not define orientation or direction in mutually understood terms, resulting in the creation of an incorrect mirror image of the structure – a common phenomenon seen during the teaching of procedures in the clinical learning environment. The workshop was well received. Students made requests to have similar sessions throughout their training to better support the development of effective communication skills. The workshop can easily be applied to other specialties to assist with procedural skills instruction or in workshops focusing on effective communication. PMID:29568715

La reivindicación del saber lego en la defensa de la salud pública: Erin Brockovich

Directory of Open Access Journals (Sweden)

Alfredo MENÉNDEZ-NAVARRO

2016-09-01

Full Text Available Basada en hechos reales, Erin Brockovich narra la singular labor de esta mujer sin formación legal y un complicado contexto familiar en la preparación y desenlace de una exitosa demanda contra la Pacific Gas and Electric Company por contaminación de aguas de consumo humano con cromo hexavalente en Hinkley (California, EE.UU.. La película permite acercarnos a las estrategias de ocultación de riesgos ambientales de las grandes corporaciones industriales así como reivindicar el valor del conocimiento lego y del empoderamiento de los ciudadanos en la defensa del derecho a la salud.

RATIONAL RECOVERY MODEL OF DEPOT PROCESSING EQUIPMENT AT THE INDUSTRIAL ENTERPRISE

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M. I. Kapitsa

2014-07-01

Full Text Available Purpose. The problem of the maximum resources recovery of rolling stock repair depot of industrial enterprise with limited resources consumption, which are used in the system is today’s topical question.The main factors that affect the repair depot operation of industrial enterprise are reviewed. The most significant factors, affecting the quality of the repair depot, are emphasized for further study, specifically - the state of the major repair equipment of a sector. There is a need to minimize the impact of the unsatisfactory state of this factor. Methodology. The formed task of major equipment rational repairing in the mathematical sense is based on the solution of a vector optimization problem. In this case the target functions are the monetary funds spending and time expenditure for repairing. Findings. The mathematical model of optimal equipment maintainability of the repair department at the industrial enterprise was developed by the authors. On the example the choice model of optimal path for equipment repairing of enterprise repair department is described. Originality. As a result of the conducted research the repairing system of major equipment of industrial enterprise sectors was improved. As the mathematical model of rational system recovery of industrial enterprise repair depot we recommend apparatus of class problems of vector optimization. Practical value. Using the proposed model of major equipment repair system of the repair depot at the industrial enterprise will improve the quality of the department by increasing the efficiency of primary resources - time and monetary funds - which are spent by the sector in order to repair its techniques.

A static investigation of yaw vectoring concepts on two-dimensional convergent-divergent nozzles

Science.gov (United States)

Berrier, B. L.; Mason, M. L.

1983-01-01

The flow-turning capability and nozzle internal performance of yaw-vectoring nozzle geometries were tested in the NASA Langley 16-ft Transonic wind tunnel. The concept was investigated as a means of enhancing fighter jet performance. Five two-dimensional convergent-divergent nozzles were equipped for yaw-vectoring and examined. The configurations included a translating left sidewall, left and right sidewall flaps downstream of the nozzle throat, left sidewall flaps or port located upstream of the nozzle throat, and a powered rudder. Trials were also run with 20 deg of pitch thrust vectoring added. The feasibility of providing yaw-thrust vectoring was demonstrated, with the largest yaw vector angles being obtained with sidewall flaps downstream of the nozzle primary throat. It was concluded that yaw vector designs that scoop or capture internal nozzle flow provide the largest yaw-vector capability, but decrease the thrust the most.

Collective Value Creation and Empowerment in an Online Brand Community: A Netnographic Study on LEGO Builders

Directory of Open Access Journals (Sweden)

Pekka Tuominen

2012-06-01

Full Text Available Online communities are becoming “places” of belonging, information, and emotional support that people cannot do without. These social groups have a real existence for their participants, and thus have consequential effects on many aspects of behaviour. This article examines collective value creation and empowerment in an online brand community. It presents the main features of an online brand community, the process of value co-creation, and motivators for participating in online brand communities. These key factors jointly characterize collective value creation and empowerment. This netnographic study focuses on an online brand community called BrickBuilders, which is a meeting place for LEGO builders in Finland. BrickBuilders’ members feel a sense of belonging, they share similar motivations, and they create value together.

The PP1 binding code: a molecular-lego strategy that governs specificity.

Science.gov (United States)

Heroes, Ewald; Lesage, Bart; Görnemann, Janina; Beullens, Monique; Van Meervelt, Luc; Bollen, Mathieu

2013-01-01

Ser/Thr protein phosphatase 1 (PP1) is a single-domain hub protein with nearly 200 validated interactors in vertebrates. PP1-interacting proteins (PIPs) are ubiquitously expressed but show an exceptional diversity in brain, testis and white blood cells. The binding of PIPs is mainly mediated by short motifs that dock to surface grooves of PP1. Although PIPs often contain variants of the same PP1 binding motifs, they differ in the number and combination of docking sites. This molecular-lego strategy for binding to PP1 creates holoenzymes with unique properties. The PP1 binding code can be described as specific, universal, degenerate, nonexclusive and dynamic. PIPs control associated PP1 by interference with substrate recruitment or access to the active site. In addition, some PIPs have a subcellular targeting domain that promotes dephosphorylation by increasing the local concentration of PP1. The diversity of the PP1 interactome and the properties of the PP1 binding code account for the exquisite specificity of PP1 in vivo. © 2012 The Authors Journal compilation © 2012 FEBS.

Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+-ATPase Inhibitors (ChemMedChem 1/2018)

DEFF Research Database (Denmark)

Thanh Tung, Truong; Dao, Trong Tuan; Grifell Junyent, Marta

2018-01-01

The Cover Feature shows a rational procedure for assembling privileged molecular fragments (like playing with LEGO bricks) to obtain hit structures. We have invented a novel procedure for targeting biological macromolecules possessing a binding site with a poorly known topography. We have coined ......, 2018 (DOI: 10.1002/cmdc.201700635)....

User-friendly freehand ultrasound calibration using Lego bricks and automatic registration.

Science.gov (United States)

Xiao, Yiming; Yan, Charles Xiao Bo; Drouin, Simon; De Nigris, Dante; Kochanowska, Anna; Collins, D Louis

2016-09-01

As an inexpensive, noninvasive, and portable clinical imaging modality, ultrasound (US) has been widely employed in many interventional procedures for monitoring potential tissue deformation, surgical tool placement, and locating surgical targets. The application requires the spatial mapping between 2D US images and 3D coordinates of the patient. Although positions of the devices (i.e., ultrasound transducer) and the patient can be easily recorded by a motion tracking system, the spatial relationship between the US image and the tracker attached to the US transducer needs to be estimated through an US calibration procedure. Previously, various calibration techniques have been proposed, where a spatial transformation is computed to match the coordinates of corresponding features in a physical phantom and those seen in the US scans. However, most of these methods are difficult to use for novel users. We proposed an ultrasound calibration method by constructing a phantom from simple Lego bricks and applying an automated multi-slice 2D-3D registration scheme without volumetric reconstruction. The method was validated for its calibration accuracy and reproducibility. Our method yields a calibration accuracy of [Formula: see text] mm and a calibration reproducibility of 1.29 mm. We have proposed a robust, inexpensive, and easy-to-use ultrasound calibration method.

Self-adjointness of the Gaffney Laplacian on Vector Bundles

International Nuclear Information System (INIS)

Bandara, Lashi; Milatovic, Ognjen

2015-01-01

We study the Gaffney Laplacian on a vector bundle equipped with a compatible metric and connection over a Riemannian manifold that is possibly geodesically incomplete. Under the hypothesis that the Cauchy boundary is polar, we demonstrate the self-adjointness of this Laplacian. Furthermore, we show that negligible boundary is a necessary and sufficient condition for the self-adjointness of this operator

Self-adjointness of the Gaffney Laplacian on Vector Bundles

Energy Technology Data Exchange (ETDEWEB)

Bandara, Lashi, E-mail: lashi.bandara@chalmers.se [Chalmers University of Technology and University of Gothenburg, Mathematical Sciences (Sweden); Milatovic, Ognjen, E-mail: omilatov@unf.edu [University of North Florida, Department of Mathematics and Statistics (United States)

2015-12-15

We study the Gaffney Laplacian on a vector bundle equipped with a compatible metric and connection over a Riemannian manifold that is possibly geodesically incomplete. Under the hypothesis that the Cauchy boundary is polar, we demonstrate the self-adjointness of this Laplacian. Furthermore, we show that negligible boundary is a necessary and sufficient condition for the self-adjointness of this operator.

Improvement in vehicle agility and stability by G-Vectoring control

Science.gov (United States)

Yamakado, Makoto; Takahashi, Jyunya; Saito, Shinjiro; Yokoyama, Atsushi; Abe, Masato

2010-12-01

We extracted a trade-off strategy between longitudinal traction/braking force and cornering force by using jerk information through observing an expert driver's voluntary braking and turning action. Using the expert driver's strategy, we developed a new control concept, called 'G-Vectoring control', which is an automatic longitudinal acceleration control (No DYC) in accordance with the vehicle's lateral jerk caused by the driver's steering manoeuvres. With the control, the direction of synthetic acceleration (G) changes seamlessly (i.e. vectoring). The improvements in vehicle agility and stability were evaluated by theoretical analysis and through computer simulation. We then introduced a 'G-Vectoring' equipped test vehicle realised by brake-by-wire technology and executed a detailed examination on a test track. We have confirmed that the vehicle motion in view of both handling and ride quality has improved dramatically.

Memory and accurate processing brain rehabilitation for the elderly: LEGO robot and iPad case study.

Science.gov (United States)

Lopez-Samaniego, Leire; Garcia-Zapirain, Begonya; Mendez-Zorrilla, Amaia

2014-01-01

This paper presents the results of research that applies cognitive therapies associated with memory and mathematical problem-solving in elderly people. The exercises are programmed in an iPad and can be performed both from the Tablet and in an interactive format with a LEGO robot. The system has been tested with 2 men and 7 women over the age of 65 who have slight physical and cognitive impairment. Evaluation with the SUS resulted in a mean of 48.45 with a standard deviation of 5.82. The score of overall satisfaction was 84.37 with a standard deviation of 18.6. Interaction with the touch screen caused some usability problems due to the elderly people's visual difficulties and clicking accuracy. Future versions will include visualization with more color contrast and less use of the keyboard.

Modulating ectopic gene expression levels by using retroviral vectors equipped with synthetic promoters

OpenAIRE

Ferreira, Joshua P.; Peacock, Ryan W. S.; Lawhorn, Ingrid E. B.; Wang, Clifford L.

2011-01-01

The human cytomegalovirus and elongation factor 1α promoters are constitutive promoters commonly employed by mammalian expression vectors. These promoters generally produce high levels of expression in many types of cells and tissues. To generate a library of synthetic promoters capable of generating a range of low, intermediate, and high expression levels, the TATA and CAAT box elements of these promoters were mutated. Other promoter variants were also generated by random mutagenesis. Evalua...

The Lie Bracket of Adapted Vector Fields on Wiener Spaces

International Nuclear Information System (INIS)

Driver, B. K.

1999-01-01

Let W(M) be the based (at o element of M) path space of a compact Riemannian manifold M equipped with Wiener measure ν . This paper is devoted to considering vector fields on W(M) of the form X s h (σ )=P s (σ)h s (σ ) where P s (σ ) denotes stochastic parallel translation up to time s along a Wiener path σ element of W(M) and {h s } i sanelementof [0,1] is an adapted T o M -valued process on W(M). It is shown that there is a large class of processes h (called adapted vector fields) for which we may view X h as first-order differential operators acting on functions on W(M) . Moreover, if h and k are two such processes, then the commutator of X h with X k is again a vector field on W(M) of the same form

Bioengineering a non-genotoxic vector for genetic modification of mesenchymal stem cells.

Science.gov (United States)

Chen, Xuguang; Nomani, Alireza; Patel, Niket; Nouri, Faranak S; Hatefi, Arash

2018-01-01

Vectors used for stem cell transfection must be non-genotoxic, in addition to possessing high efficiency, because they could potentially transform normal stem cells into cancer-initiating cells. The objective of this research was to bioengineer an efficient vector that can be used for genetic modification of stem cells without any negative somatic or genetic impact. Two types of multifunctional vectors, namely targeted and non-targeted were genetically engineered and purified from E. coli. The targeted vectors were designed to enter stem cells via overexpressed receptors. The non-targeted vectors were equipped with MPG and Pep1 cell penetrating peptides. A series of commercial synthetic non-viral vectors and an adenoviral vector were used as controls. All vectors were evaluated for their efficiency and impact on metabolic activity, cell membrane integrity, chromosomal aberrations (micronuclei formation), gene dysregulation, and differentiation ability of stem cells. The results of this study showed that the bioengineered vector utilizing VEGFR-1 receptors for cellular entry could transfect mesenchymal stem cells with high efficiency without inducing genotoxicity, negative impact on gene function, or ability to differentiate. Overall, the vectors that utilized receptors as ports for cellular entry (viral and non-viral) showed considerably better somato- and genosafety profiles in comparison to those that entered through electrostatic interaction with cellular membrane. The genetically engineered vector in this study demonstrated that it can be safely and efficiently used to genetically modify stem cells with potential applications in tissue engineering and cancer therapy. Copyright © 2017 Elsevier Ltd. All rights reserved.

Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor

Directory of Open Access Journals (Sweden)

Jonathan Sheu

Full Text Available Lentiviral vectors are widely used in the field of gene therapy as an effective method for permanent gene delivery. While current methods of producing small scale vector batches for research purposes depend largely on culture flasks, the emergence and popularity of lentiviral vectors in translational, preclinical and clinical research has demanded their production on a much larger scale, a task that can be difficult to manage with the numbers of producer cell culture flasks required for large volumes of vector. To generate a large scale, partially closed system method for the manufacturing of clinical grade lentiviral vector suitable for the generation of induced pluripotent stem cells (iPSCs, we developed a method employing a hollow fiber bioreactor traditionally used for cell expansion. We have demonstrated the growth, transfection, and vector-producing capability of 293T producer cells in this system. Vector particle RNA titers after subsequent vector concentration yielded values comparable to lentiviral iPSC induction vector batches produced using traditional culture methods in 225 cm2 flasks (T225s and in 10-layer cell factories (CF10s, while yielding a volume nearly 145 times larger than the yield from a T225 flask and nearly three times larger than the yield from a CF10. Employing a closed system hollow fiber bioreactor for vector production offers the possibility of manufacturing large quantities of gene therapy vector while minimizing reagent usage, equipment footprint, and open system manipulation.

Physicochemical, morphological, and rheological characterization of Xanthosoma robustum Lego-like starch.

Science.gov (United States)

Londoño-Restrepo, Sandra M; Rincón-Londoño, Natalia; Contreras-Padilla, Margarita; Acosta-Osorio, Andrés A; Bello-Pérez, Luis A; Lucas-Aguirre, Juan C; Quintero, Víctor D; Pineda-Gómez, Posidia; del Real-López, Alicia; Rodríguez-García, Mario E

2014-04-01

This work presents the physicochemical and pasting characterization of isolated mafafa starch and mafafa flour (Xanthosoma robustum). According to SEM images of mafafa starches in the tuber, these starches form Lego-like shaped structures with diameters between 8 and 35 μm conformed by several starch granules of wedge shape that range from 2 to 7 μm. The isolated mafafa starch is characterized by its low contents of protein, fat, and ash. The starch content in isolated starch was found to be 88.58% while the amylose content obtained was 35.43%. X-ray diffraction studies confirm that isolated starch is composed mainly by amylopectin. These results were confirmed by differential scanning calorimetry and thermo gravimetric analysis. This is the first report of the molecular parameters for mafafa starch: molar mass that ranged between 2×10(8) and 4×10(8) g/mol, size (Rg) value between 279 and 295 nm, and molecular density value between 9.2 and 9.7 g/(mol nm(3)). This study indicates that mafafa starch shows long chains of amylopectin this fact contributes to higher viscosity development and higher gel stability. The obtained gel phase is transparent in the UV-vis region. The viscosity, gel stability and optical properties suggest that there is potential for mafafa starch applications in the food industry. Copyright © 2014 Elsevier B.V. All rights reserved.

Paralleled comparison of vectors for the generation of CAR-T cells.

Science.gov (United States)

Qin, Di-Yuan; Huang, Yong; Li, Dan; Wang, Yong-Sheng; Wang, Wei; Wei, Yu-Quan

2016-09-01

T-lymphocytes genetically engineered with the chimeric antigen receptor (CAR-T) have shown great therapeutic potential in cancer treatment. A variety of preclinical researches and clinical trials of CAR-T therapy have been carried out to lay the foundation for future clinical application. In these researches, several gene-transfer methods were used to deliver CARs or other genes into T-lymphocytes, equipping CAR-modified T cells with a property of recognizing and attacking antigen-expressing tumor cells in a major histocompatibility complex-independent manner. Here, we summarize the gene-transfer vectors commonly used in the generation of CAR-T cell, including retrovirus vectors, lentivirus vectors, the transposon/transposase system, the plasmid-based system, and the messenger RNA electroporation system. The following aspects were compared in parallel: efficiency of gene transfer, the integration methods in the modified T cells, foreground of scale-up production, and application and development in clinical trials. These aspects should be taken into account to generate the optimal CAR-gene vector that may be suitable for future clinical application.

Differential calculi on quantum vector spaces with Hecke-type relations

International Nuclear Information System (INIS)

Baez, J.C.

1991-01-01

From a vector space V equipped with a Yang-Baxter operator R one may form the r-symmetric algebra S R V=TV/ , which is a quantum vector space in the sense of Manin, and the associated quantum matrix algebra M R V=T(End(V))/ -1 >. In the case when R satisfies a Hecke-type identity R 2 =(1-q)R+q, we construct a differential calculus Ω R V for S R V which agrees with that constructed by Pusz, Woronowicz, Wess, and Zumino when R is essentially the R-matrix of GL q (n). Elements of Ω R V may be regarded as differential forms on the quantum vector space S R V. We show that Ω R V is M R V-covariant in the sense that there is a coaction Φ * :Ω R V→M R VxΩ R V with Φ * d=(1xd)Φ * extending the natural coaction Φ:S R V→M R VxS R V. (orig.)

Designing using Lego and Uno-Stacko: A Playful Architecture for an Integrated Kindergarten and Elementary School

Science.gov (United States)

Muthmainnah, K.; Aryanti, T.; Ardiansyah, A.

2017-03-01

The integrated kindergarten and elementary school is a public educational facility used for early age and elementary education. Designated for children at 4-12 years of age, the design should meet the standards and requirements, while considering children’s needs in their development phase. This paper discusses the design of an integrated kindergarten and elementary school using the playful theme. Design was explored using LEGO and UNO-STACKO to create spaces that accommodate material exploration for children. The design takes the play concept as a medium of child’s learning in order to improve their ability and awareness of the surrounding environment. The design translates the playful theme into imaginary dimension, constructive-deconstructive shapes, and glide circulations concept. The spatial pattern is applied by considering children’s behavior in the designated ages to trigger their creativity improvement. The design is expected to serve as a model of an integrated kindergarten and elementary school architecture.

Introducir la fracción en el ámbito escolar a través de un material manipulativo como es el Lego

OpenAIRE

Sánchez Díaz, Michael

2017-01-01

Treball Final de Grau en Mestre o Mestra d'Educació Primària. Codi: MP1040. Curs acadèmic: 2016/2017 Con este trabajo de investigación se quiere proponer una nueva metodología a la hora de enseñar las fracciones en la asignatura de matemáticas en el aula de primaria. El principal objetivo a seguir es que, a través de un material manipulativo como es el lego, los niños sean capaces de aprender las nociones básicas sobre las fracciones haciendo y no escuchando. Para ello, se ha ido recogiend...

Lego Serious Play: hacia la permeabilidad del pensamiento crítico

Directory of Open Access Journals (Sweden)

Miriam Peña-Zabala

2018-01-01

Full Text Available INTRODUCCIÓN. La presente investigación indaga sobre la importancia de relacionar la enseñanza-aprendizaje con el acto de reflexionar. La hipótesis parte de la creencia de que reflexionar favorece el desarrollo del pensamiento crítico en el alumnado, y así, la comprensión y asimilación de las prácticas educativas vinculadas al arte contemporáneo en la formación inicial de profesorado. MÉTODO. Una vez definidas las preguntas de investigación, se ha optado por el método Lego Serious Play (LSP para llevar a cabo una sesión en la que se dialoga en torno a prácticas artísticas desarrolladas en el aula. Este método analiza la idea del juego simbólico como constructor de conocimiento y, por tanto, como una posible herramienta canalizadora hacia el pensamiento reflexivo. RESULTADOS. Los relatos extraídos han permitido ver resultados significativos que posibilitan mediar entre las prácticas artísticas desarrolladas y experiencias de vida, demostrando el uso de LSP para dicho cometido. DISCUSIÓN. Se pone en valor la diversidad y versatilidad que ofrece el acto de reflexionar, lo cual supone una vía significativa hacia el pensamiento crítico. También se subraya la idea de rescatar el juego como una herramienta eficaz en la educación adulta.

Emerging Vector-Borne Diseases - Incidence through Vectors.

Science.gov (United States)

Savić, Sara; Vidić, Branka; Grgić, Zivoslav; Potkonjak, Aleksandar; Spasojevic, Ljubica

2014-01-01

Vector-borne diseases use to be a major public health concern only in tropical and subtropical areas, but today they are an emerging threat for the continental and developed countries also. Nowadays, in intercontinental countries, there is a struggle with emerging diseases, which have found their way to appear through vectors. Vector-borne zoonotic diseases occur when vectors, animal hosts, climate conditions, pathogens, and susceptible human population exist at the same time, at the same place. Global climate change is predicted to lead to an increase in vector-borne infectious diseases and disease outbreaks. It could affect the range and population of pathogens, host and vectors, transmission season, etc. Reliable surveillance for diseases that are most likely to emerge is required. Canine vector-borne diseases represent a complex group of diseases including anaplasmosis, babesiosis, bartonellosis, borreliosis, dirofilariosis, ehrlichiosis, and leishmaniosis. Some of these diseases cause serious clinical symptoms in dogs and some of them have a zoonotic potential with an effect to public health. It is expected from veterinarians in coordination with medical doctors to play a fundamental role at primarily prevention and then treatment of vector-borne diseases in dogs. The One Health concept has to be integrated into the struggle against emerging diseases. During a 4-year period, from 2009 to 2013, a total number of 551 dog samples were analyzed for vector-borne diseases (borreliosis, babesiosis, ehrlichiosis, anaplasmosis, dirofilariosis, and leishmaniasis) in routine laboratory work. The analysis was done by serological tests - ELISA for borreliosis, dirofilariosis, and leishmaniasis, modified Knott test for dirofilariosis, and blood smear for babesiosis, ehrlichiosis, and anaplasmosis. This number of samples represented 75% of total number of samples that were sent for analysis for different diseases in dogs. Annually, on average more then half of the samples

μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips.

Directory of Open Access Journals (Sweden)

Peter Loskill

Full Text Available Human organ-on-a-chip systems for drug screening have evolved as feasible alternatives to animal models, which are unreliable, expensive, and at times erroneous. While chips featuring single organs can be of great use for both pharmaceutical testing and basic organ-level studies, the huge potential of the organ-on-a-chip technology is revealed by connecting multiple organs on one chip to create a single integrated system for sophisticated fundamental biological studies and devising therapies for disease. Furthermore, since most organ-on-a-chip systems require special protocols with organ-specific media for the differentiation and maturation of the tissues, multi-organ systems will need to be temporally customizable and flexible in terms of the time point of connection of the individual organ units. We present a customizable Lego®-like plug & play system, μOrgano, which enables initial individual culture of single organ-on-a-chip systems and subsequent connection to create integrated multi-organ microphysiological systems. As a proof of concept, the μOrgano system was used to connect multiple heart chips in series with excellent cell viability and spontaneously physiological beat rates.

First Steps into Practical Engineering for Freshman Students Using MATLAB and LEGO Mindstorms Robots

Directory of Open Access Journals (Sweden)

A. Behrens

2008-01-01

Full Text Available Besides lectures on basic theoretical topics, contemporary teaching and learning concepts for first semester students give more and more consideration to practically motivated courses. In this context, a new first-year introductory course in practical engineering has been established in the first semester curriculum of Electrical Engineering at RWTH Aachen University, Germany. Based on a threefold learning concept, programming skills in MATLAB are taught to 309 students within a full-time block course laboratory. The students are encouraged to transfer known mathematical basics to program algorithms and real-world applications performed by 100 LEGO Mindstorms robots. A new MATLAB toolbox and twofold project tasks have been developed for this purpose by a small team of supervisors. The students are supervised by over 60 tutors at 23 institutes, and are encouraged to create their own robotics applications. We describe how the laboratory motivates the students to act and think like engineers and to solve real-world issues with limited resources. The evaluation results show that the proposed practical course concept successfully boosts students’ motivation, advances their programming skills, and encourages the peer learning process. 

μOrgano: A Lego®-Like Plug & Play System for Modular Multi-Organ-Chips.

Science.gov (United States)

Loskill, Peter; Marcus, Sivan G; Mathur, Anurag; Reese, Willie Mae; Healy, Kevin E

2015-01-01

Human organ-on-a-chip systems for drug screening have evolved as feasible alternatives to animal models, which are unreliable, expensive, and at times erroneous. While chips featuring single organs can be of great use for both pharmaceutical testing and basic organ-level studies, the huge potential of the organ-on-a-chip technology is revealed by connecting multiple organs on one chip to create a single integrated system for sophisticated fundamental biological studies and devising therapies for disease. Furthermore, since most organ-on-a-chip systems require special protocols with organ-specific media for the differentiation and maturation of the tissues, multi-organ systems will need to be temporally customizable and flexible in terms of the time point of connection of the individual organ units. We present a customizable Lego®-like plug & play system, μOrgano, which enables initial individual culture of single organ-on-a-chip systems and subsequent connection to create integrated multi-organ microphysiological systems. As a proof of concept, the μOrgano system was used to connect multiple heart chips in series with excellent cell viability and spontaneously physiological beat rates.

Vector analysis

CERN Document Server

Newell, Homer E

2006-01-01

When employed with skill and understanding, vector analysis can be a practical and powerful tool. This text develops the algebra and calculus of vectors in a manner useful to physicists and engineers. Numerous exercises (with answers) not only provide practice in manipulation but also help establish students' physical and geometric intuition in regard to vectors and vector concepts.Part I, the basic portion of the text, consists of a thorough treatment of vector algebra and the vector calculus. Part II presents the illustrative matter, demonstrating applications to kinematics, mechanics, and e

Vector-Tensor and Vector-Vector Decay Amplitude Analysis of B0→φK*0

International Nuclear Information System (INIS)

Aubert, B.; Bona, M.; Boutigny, D.; Couderc, F.; Karyotakis, Y.; Lees, J. P.; Poireau, V.; Tisserand, V.; Zghiche, A.; Grauges, E.; Palano, A.; Chen, J. C.; Qi, N. D.; Rong, G.; Wang, P.; Zhu, Y. S.; Eigen, G.; Ofte, I.; Stugu, B.; Abrams, G. S.

2007-01-01

We perform an amplitude analysis of the decays B 0 →φK 2 * (1430) 0 , φK * (892) 0 , and φ(Kπ) S-wave 0 with a sample of about 384x10 6 BB pairs recorded with the BABAR detector. The fractions of longitudinal polarization f L of the vector-tensor and vector-vector decay modes are measured to be 0.853 -0.069 +0.061 ±0.036 and 0.506±0.040±0.015, respectively. Overall, twelve parameters are measured for the vector-vector decay and seven parameters for the vector-tensor decay, including the branching fractions and parameters sensitive to CP violation

About vectors

CERN Document Server

Hoffmann, Banesh

1975-01-01

From his unusual beginning in ""Defining a vector"" to his final comments on ""What then is a vector?"" author Banesh Hoffmann has written a book that is provocative and unconventional. In his emphasis on the unresolved issue of defining a vector, Hoffmann mixes pure and applied mathematics without using calculus. The result is a treatment that can serve as a supplement and corrective to textbooks, as well as collateral reading in all courses that deal with vectors. Major topics include vectors and the parallelogram law; algebraic notation and basic ideas; vector algebra; scalars and scalar p

Vectors

DEFF Research Database (Denmark)

Boeriis, Morten; van Leeuwen, Theo

2017-01-01

should be taken into account in discussing ‘reactions’, which Kress and van Leeuwen link only to eyeline vectors. Finally, the question can be raised as to whether actions are always realized by vectors. Drawing on a re-reading of Rudolf Arnheim’s account of vectors, these issues are outlined......This article revisits the concept of vectors, which, in Kress and van Leeuwen’s Reading Images (2006), plays a crucial role in distinguishing between ‘narrative’, action-oriented processes and ‘conceptual’, state-oriented processes. The use of this concept in image analysis has usually focused...

Vector regression introduced

Directory of Open Access Journals (Sweden)

Mok Tik

2014-06-01

Full Text Available This study formulates regression of vector data that will enable statistical analysis of various geodetic phenomena such as, polar motion, ocean currents, typhoon/hurricane tracking, crustal deformations, and precursory earthquake signals. The observed vector variable of an event (dependent vector variable is expressed as a function of a number of hypothesized phenomena realized also as vector variables (independent vector variables and/or scalar variables that are likely to impact the dependent vector variable. The proposed representation has the unique property of solving the coefficients of independent vector variables (explanatory variables also as vectors, hence it supersedes multivariate multiple regression models, in which the unknown coefficients are scalar quantities. For the solution, complex numbers are used to rep- resent vector information, and the method of least squares is deployed to estimate the vector model parameters after transforming the complex vector regression model into a real vector regression model through isomorphism. Various operational statistics for testing the predictive significance of the estimated vector parameter coefficients are also derived. A simple numerical example demonstrates the use of the proposed vector regression analysis in modeling typhoon paths.

PROCESAMIENTO DE IMÁGENES PARA LA PLANEACIÓN DE RUTAS PARA ROBOTS MÓVILES BASADOS EN LEGO MINDSTORMS NXT

Directory of Open Access Journals (Sweden)

Jesús Alberto Torres Velásquez

2014-11-01

Full Text Available El presente artículo contiene el procedimiento para implementar diferentes técnicas de procesamiento de  imágenes y principalmente el algoritmo de esqueletización con el objetivo de planificar rutas libres de obstáculos para robots móviles; mediante una fotografía tomada sobre un área determinada con los obstáculos y el robot (construido con el kit de robótica LEGO MINDSTORMS NXT. Se realiza el debido procesamiento a dicha imagen, para luego, de forma remota enviar una serie de órdenes vía Bluetooth desde un computador usando MATLAB; ordenes generadas por el algoritmo aplicado sobre la imagen ya procesada, con el fin de obtener el desplazamiento de la plataforma móvil a un punto de llegada determinado por el usuario. 

Kochen-Specker vectors

International Nuclear Information System (INIS)

Pavicic, Mladen; Merlet, Jean-Pierre; McKay, Brendan; Megill, Norman D

2005-01-01

We give a constructive and exhaustive definition of Kochen-Specker (KS) vectors in a Hilbert space of any dimension as well as of all the remaining vectors of the space. KS vectors are elements of any set of orthonormal states, i.e., vectors in an n-dimensional Hilbert space, H n , n≥3, to which it is impossible to assign 1s and 0s in such a way that no two mutually orthogonal vectors from the set are both assigned 1 and that not all mutually orthogonal vectors are assigned 0. Our constructive definition of such KS vectors is based on algorithms that generate MMP diagrams corresponding to blocks of orthogonal vectors in R n , on algorithms that single out those diagrams on which algebraic (0)-(1) states cannot be defined, and on algorithms that solve nonlinear equations describing the orthogonalities of the vectors by means of statistically polynomially complex interval analysis and self-teaching programs. The algorithms are limited neither by the number of dimensions nor by the number of vectors. To demonstrate the power of the algorithms, all four-dimensional KS vector systems containing up to 24 vectors were generated and described, all three-dimensional vector systems containing up to 30 vectors were scanned, and several general properties of KS vectors were found

Elementary vectors

CERN Document Server

Wolstenholme, E Œ

1978-01-01

Elementary Vectors, Third Edition serves as an introductory course in vector analysis and is intended to present the theoretical and application aspects of vectors. The book covers topics that rigorously explain and provide definitions, principles, equations, and methods in vector analysis. Applications of vector methods to simple kinematical and dynamical problems; central forces and orbits; and solutions to geometrical problems are discussed as well. This edition of the text also provides an appendix, intended for students, which the author hopes to bridge the gap between theory and appl

The Spin Torque Lego - from spin torque nano-devices to advanced computing architectures

Science.gov (United States)

Grollier, Julie

2013-03-01

Spin transfer torque (STT), predicted in 1996, and first observed around 2000, brought spintronic devices to the realm of active elements. A whole class of new devices, based on the combined effects of STT for writing and Giant Magneto-Resistance or Tunnel Magneto-Resistance for reading has emerged. The second generation of MRAMs, based on spin torque writing : the STT-RAM, is under industrial development and should be out on the market in three years. But spin torque devices are not limited to binary memories. We will rapidly present how the spin torque effect also allows to implement non-linear nano-oscillators, spin-wave emitters, controlled stochastic devices and microwave nano-detectors. What is extremely interesting is that all these functionalities can be obtained using the same materials, the exact same stack, simply by changing the device geometry and its bias conditions. So these different devices can be seen as Lego bricks, each brick with its own functionality. During this talk, I will show how spin torque can be engineered to build new bricks, such as the Spintronic Memristor, an artificial magnetic nano-synapse. I will then give hints on how to assemble these bricks in order to build novel types of computing architectures, with a special focus on neuromorphic circuits. Financial support by the European Research Council Starting Grant NanoBrain (ERC 2010 Stg 259068) is acknowledged.

Genetic manipulation of endosymbionts to control vector and vector borne diseases

Directory of Open Access Journals (Sweden)

Jay Prakash Gupta

Full Text Available Vector borne diseases (VBD are on the rise because of failure of the existing methods of control of vector and vector borne diseases and the climate change. A steep rise of VBDs are due to several factors like selection of insecticide resistant vector population, drug resistant parasite population and lack of effective vaccines against the VBDs. Environmental pollution, public health hazard and insecticide resistant vector population indicate that the insecticides are no longer a sustainable control method of vector and vector-borne diseases. Amongst the various alternative control strategies, symbiont based approach utilizing endosymbionts of arthropod vectors could be explored to control the vector and vector borne diseases. The endosymbiont population of arthropod vectors could be exploited in different ways viz., as a chemotherapeutic target, vaccine target for the control of vectors. Expression of molecules with antiparasitic activity by genetically transformed symbiotic bacteria of disease-transmitting arthropods may serve as a powerful approach to control certain arthropod-borne diseases. Genetic transformation of symbiotic bacteria of the arthropod vector to alter the vector’s ability to transmit pathogen is an alternative means of blocking the transmission of VBDs. In Indian scenario, where dengue, chikungunya, malaria and filariosis are prevalent, paratransgenic based approach can be used effectively. [Vet World 2012; 5(9.000: 571-576

Emerging vector borne diseases – incidence through vectors

Directory of Open Access Journals (Sweden)

Sara eSavic

2014-12-01

Full Text Available Vector borne diseases use to be a major public health concern only in tropical and subtropical areas, but today they are an emerging threat for the continental and developed countries also. Nowdays, in intercontinetal countries, there is a struggle with emerging diseases which have found their way to appear through vectors. Vector borne zoonotic diseases occur when vectors, animal hosts, climate conditions, pathogens and susceptible human population exist at the same time, at the same place. Global climate change is predicted to lead to an increase in vector borne infectious diseases and disease outbreaks. It could affect the range and popultion of pathogens, host and vectors, transmission season, etc. Reliable surveilance for diseases that are most likely to emerge is required. Canine vector borne diseases represent a complex group of diseases including anaplasmosis, babesiosis, bartonellosis, borreliosis, dirofilariosis, erlichiosis, leishmaniosis. Some of these diseases cause serious clinical symptoms in dogs and some of them have a zoonotic potential with an effect to public health. It is expected from veterinarians in coordination with medical doctors to play a fudamental role at primeraly prevention and then treatment of vector borne diseases in dogs. The One Health concept has to be integrated into the struggle against emerging diseases.During a four year period, from 2009-2013, a total number of 551 dog samples were analysed for vector borne diseases (borreliosis, babesiosis, erlichiosis, anaplasmosis, dirofilariosis and leishmaniasis in routine laboratory work. The analysis were done by serological tests – ELISA for borreliosis, dirofilariosis and leishmaniasis, modified Knott test for dirofilariosis and blood smear for babesiosis, erlichiosis and anaplasmosis. This number of samples represented 75% of total number of samples that were sent for analysis for different diseases in dogs. Annually, on avarege more then half of the samples

Sn transport calculations on vector and parallel processors

International Nuclear Information System (INIS)

Rhoades, W.A.; Childs, R.L.

1987-01-01

The transport of radiation from the source to the location of people or equipment gives rise to some of the most challenging of calculations. A problem may involve as many as a billion unknowns, each evaluated several times to resolve interdependence. Such calculations run many hours on a Cray computer, and a typical study involves many such calculations. This paper will discuss the steps taken to vectorize the DOT code, which solves transport problems in two space dimensions (2-D); the extension of this code to 3-D; and the plans for extension to parallel processors

Vector-vector production in photon-photon interactions

International Nuclear Information System (INIS)

Ronan, M.T.

1988-01-01

Measurements of exclusive untagged /rho/ 0 /rho/ 0 , /rho//phi/, K/sup *//bar K//sup */, and /rho/ω production and tagged /rho/ 0 /rho/ 0 production in photon-photon interactions by the TPC/Two-Gamma experiment are reviewed. Comparisons to the results of other experiments and to models of vector-vector production are made. Fits to the data following a four quark model prescription for vector meson pair production are also presented. 10 refs., 9 figs

GNSS Single Frequency, Single Epoch Reliable Attitude Determination Method with Baseline Vector Constraint

Directory of Open Access Journals (Sweden)

Ang Gong

2015-12-01

Full Text Available For Global Navigation Satellite System (GNSS single frequency, single epoch attitude determination, this paper proposes a new reliable method with baseline vector constraint. First, prior knowledge of baseline length, heading, and pitch obtained from other navigation equipment or sensors are used to reconstruct objective function rigorously. Then, searching strategy is improved. It substitutes gradually Enlarged ellipsoidal search space for non-ellipsoidal search space to ensure correct ambiguity candidates are within it and make the searching process directly be carried out by least squares ambiguity decorrelation algorithm (LAMBDA method. For all vector candidates, some ones are further eliminated by derived approximate inequality, which accelerates the searching process. Experimental results show that compared to traditional method with only baseline length constraint, this new method can utilize a priori baseline three-dimensional knowledge to fix ambiguity reliably and achieve a high success rate. Experimental tests also verify it is not very sensitive to baseline vector error and can perform robustly when angular error is not great.

Rare Hadronic B Decays to Vector, Axial-Vector and Tensors

International Nuclear Information System (INIS)

Gao, Y.Y.

2011-01-01

The authors review BABAR measurements of several rare B decays, including vector-axial-vector decays B ± → φK 1 ± (1270), B ± → φ K 1 ± (1400) and B ± → b 1 # -+ρ# ± , vector-vector decays B ± → φK* ± (1410), B 0 → K* 0 (bar K)* 0 , B 0 → K*0K*0 and B 0 → K*+K*-, vector-tensor decays B ± → φK* 2 (1430) ± and φK 2 (1770)/ ± (1820), and vector-scalar decays B ± → φK* 0 (1430) ± . Understanding the observed polarization pattern requires amplitude contributions from an uncertain source.

Vector analysis

CERN Document Server

Brand, Louis

2006-01-01

The use of vectors not only simplifies treatments of differential geometry, mechanics, hydrodynamics, and electrodynamics, but also makes mathematical and physical concepts more tangible and easy to grasp. This text for undergraduates was designed as a short introductory course to give students the tools of vector algebra and calculus, as well as a brief glimpse into these subjects' manifold applications. The applications are developed to the extent that the uses of the potential function, both scalar and vector, are fully illustrated. Moreover, the basic postulates of vector analysis are brou

Vectors and Rotations in 3-Dimensions: Vector Algebra for the C++ Programmer

Science.gov (United States)

2016-12-01

release; distribution is unlimited. 1. Introduction This report describes 2 C++ classes: a Vector class for performing vector algebra in 3-dimensional...ARL-TR-7894•DEC 2016 US Army Research Laboratory Vectors and Rotations in 3-Dimensions:Vector Algebra for the C++ Programmer by Richard Saucier...Army Research Laboratory Vectors and Rotations in 3-Dimensions:Vector Algebra for the C++ Programmer by Richard Saucier Survivability/Lethality

All ASD complex and real 4-dimensional Einstein spaces with Λ≠0 admitting a nonnull Killing vector

Science.gov (United States)

Chudecki, Adam

2016-12-01

Anti-self-dual (ASD) 4-dimensional complex Einstein spaces with nonzero cosmological constant Λ equipped with a nonnull Killing vector are considered. It is shown that any conformally nonflat metric of such spaces can be always brought to a special form and the Einstein field equations can be reduced to the Boyer-Finley-Plebański equation (Toda field equation). Some alternative forms of the metric are discussed. All possible real slices (neutral, Euclidean and Lorentzian) of ASD complex Einstein spaces with Λ≠0 admitting a nonnull Killing vector are found.

Measurement of Charmless B to Vector-Vector decays at BaBar

International Nuclear Information System (INIS)

Olaiya, Emmanuel

2011-01-01

The authors present results of B → vector-vector (VV) and B → vector-axial vector (VA) decays B 0 → φX(X = φ,ρ + or ρ 0 ), B + → φK (*)+ , B 0 → K*K*, B 0 → ρ + b 1 - and B + → K* 0 α 1 + . The largest dataset used for these results is based on 465 x 10 6 Υ(4S) → B(bar B) decays, collected with the BABAR detector at the PEP-II B meson factory located at the Stanford Linear Accelerator Center (SLAC). Using larger datasets, the BABAR experiment has provided more precise B → VV measurements, further supporting the smaller than expected longitudinal polarization fraction of B → φK*. Additional B meson to vector-vector and vector-axial vector decays have also been studied with a view to shedding light on the polarization anomaly. Taking into account the available errors, we find no disagreement between theory and experiment for these additional decays.

System for Automated Calibration of Vector Modulators

Science.gov (United States)

Lux, James; Boas, Amy; Li, Samuel

2009-01-01

Vector modulators are used to impose baseband modulation on RF signals, but non-ideal behavior limits the overall performance. The non-ideal behavior of the vector modulator is compensated using data collected with the use of an automated test system driven by a LabVIEW program that systematically applies thousands of control-signal values to the device under test and collects RF measurement data. The technology innovation automates several steps in the process. First, an automated test system, using computer controlled digital-to-analog converters (DACs) and a computer-controlled vector network analyzer (VNA) systematically can apply different I and Q signals (which represent the complex number by which the RF signal is multiplied) to the vector modulator under test (VMUT), while measuring the RF performance specifically, gain and phase. The automated test system uses the LabVIEW software to control the test equipment, collect the data, and write it to a file. The input to the Lab - VIEW program is either user-input for systematic variation, or is provided in a file containing specific test values that should be fed to the VMUT. The output file contains both the control signals and the measured data. The second step is to post-process the file to determine the correction functions as needed. The result of the entire process is a tabular representation, which allows translation of a desired I/Q value to the required analog control signals to produce a particular RF behavior. In some applications, corrected performance is needed only for a limited range. If the vector modulator is being used as a phase shifter, there is only a need to correct I and Q values that represent points on a circle, not the entire plane. This innovation has been used to calibrate 2-GHz MMIC (monolithic microwave integrated circuit) vector modulators in the High EIRP Cluster Array project (EIRP is high effective isotropic radiated power). These calibrations were then used to create

Vectorization of KENO IV code and an estimate of vector-parallel processing

International Nuclear Information System (INIS)

Asai, Kiyoshi; Higuchi, Kenji; Katakura, Jun-ichi; Kurita, Yutaka.

1986-10-01

The multi-group criticality safety code KENO IV has been vectorized and tested on FACOM VP-100 vector processor. At first the vectorized KENO IV on a scalar processor became slower than the original one by a factor of 1.4 because of the overhead introduced by the vectorization. Making modifications of algorithms and techniques for vectorization, the vectorized version has become faster than the original one by a factor of 1.4 and 3.0 on the vector processor for sample problems of complex and simple geometries, respectively. For further speedup of the code, some improvements on compiler and hardware, especially on addition of Monte Carlo pipelines to the vector processor, are discussed. Finally a pipelined parallel processor system is proposed and its performance is estimated. (author)

Versatile generation of optical vector fields and vector beams using a non-interferometric approach.

Science.gov (United States)

Tripathi, Santosh; Toussaint, Kimani C

2012-05-07

We present a versatile, non-interferometric method for generating vector fields and vector beams which can produce all the states of polarization represented on a higher-order Poincaré sphere. The versatility and non-interferometric nature of this method is expected to enable exploration of various exotic properties of vector fields and vector beams. To illustrate this, we study the propagation properties of some vector fields and find that, in general, propagation alters both their intensity and polarization distribution, and more interestingly, converts some vector fields into vector beams. In the article, we also suggest a modified Jones vector formalism to represent vector fields and vector beams.

Selection of equipment for equipment qualification

International Nuclear Information System (INIS)

Torr, K.G.

1989-01-01

This report describes the methodology applied in selecting equipment in the special safety systems for equipment qualification in the CANDU 600 MW nuclear generating stations at Gentilly 2 and Point Lepreau. Included is an explanation of the selection procedure adopted and the rationale behind the criteria used in identifying the equipment. The equipment items on the list have been grouped into three priority categories as a planning aid to AECB staff for a review of the qualification status of the special safety systems

Vectorized Monte Carlo

International Nuclear Information System (INIS)

Brown, F.B.

1981-01-01

Examination of the global algorithms and local kernels of conventional general-purpose Monte Carlo codes shows that multigroup Monte Carlo methods have sufficient structure to permit efficient vectorization. A structured multigroup Monte Carlo algorithm for vector computers is developed in which many particle events are treated at once on a cell-by-cell basis. Vectorization of kernels for tracking and variance reduction is described, and a new method for discrete sampling is developed to facilitate the vectorization of collision analysis. To demonstrate the potential of the new method, a vectorized Monte Carlo code for multigroup radiation transport analysis was developed. This code incorporates many features of conventional general-purpose production codes, including general geometry, splitting and Russian roulette, survival biasing, variance estimation via batching, a number of cutoffs, and generalized tallies of collision, tracklength, and surface crossing estimators with response functions. Predictions of vectorized performance characteristics for the CYBER-205 were made using emulated coding and a dynamic model of vector instruction timing. Computation rates were examined for a variety of test problems to determine sensitivities to batch size and vector lengths. Significant speedups are predicted for even a few hundred particles per batch, and asymptotic speedups by about 40 over equivalent Amdahl 470V/8 scalar codes arepredicted for a few thousand particles per batch. The principal conclusion is that vectorization of a general-purpose multigroup Monte Carlo code is well worth the significant effort required for stylized coding and major algorithmic changes

Vector Network Coding

OpenAIRE

Ebrahimi, Javad; Fragouli, Christina

2010-01-01

We develop new algebraic algorithms for scalar and vector network coding. In vector network coding, the source multicasts information by transmitting vectors of length L, while intermediate nodes process and combine their incoming packets by multiplying them with L X L coding matrices that play a similar role as coding coefficients in scalar coding. Our algorithms for scalar network jointly optimize the employed field size while selecting the coding coefficients. Similarly, for vector co...

Vector independent transmission of the vector-borne bluetongue virus.

Science.gov (United States)

van der Sluijs, Mirjam Tineke Willemijn; de Smit, Abraham J; Moormann, Rob J M

2016-01-01

Bluetongue is an economically important disease of ruminants. The causative agent, Bluetongue virus (BTV), is mainly transmitted by insect vectors. This review focuses on vector-free BTV transmission, and its epizootic and economic consequences. Vector-free transmission can either be vertical, from dam to fetus, or horizontal via direct contract. For several BTV-serotypes, vertical (transplacental) transmission has been described, resulting in severe congenital malformations. Transplacental transmission had been mainly associated with live vaccine strains. Yet, the European BTV-8 strain demonstrated a high incidence of transplacental transmission in natural circumstances. The relevance of transplacental transmission for the epizootiology is considered limited, especially in enzootic areas. However, transplacental transmission can have a substantial economic impact due to the loss of progeny. Inactivated vaccines have demonstrated to prevent transplacental transmission. Vector-free horizontal transmission has also been demonstrated. Since direct horizontal transmission requires close contact of animals, it is considered only relevant for within-farm spreading of BTV. The genetic determinants which enable vector-free transmission are present in virus strains circulating in the field. More research into the genetic changes which enable vector-free transmission is essential to better evaluate the risks associated with outbreaks of new BTV serotypes and to design more appropriate control measures.

VectorBase

Data.gov (United States)

U.S. Department of Health & Human Services — VectorBase is a Bioinformatics Resource Center for invertebrate vectors. It is one of four Bioinformatics Resource Centers funded by NIAID to provide web-based...

Custodial vector model

DEFF Research Database (Denmark)

Becciolini, Diego; Franzosi, Diogo Buarque; Foadi, Roshan

2015-01-01

We analyze the Large Hadron Collider (LHC) phenomenology of heavy vector resonances with a $SU(2)_L\\times SU(2)_R$ spectral global symmetry. This symmetry partially protects the electroweak S-parameter from large contributions of the vector resonances. The resulting custodial vector model spectrum...

Experimental demonstration of vector E x vector B plasma divertor

International Nuclear Information System (INIS)

Strait, E.J.; Kerst, D.W.; Sprott, J.C.

1977-01-01

The vector E x vector B drift due to an applied radial electric field in a tokamak with poloidal divertor can speed the flow of plasma out of the scrape-off region, and provide a means of externally controlling the flow rate and thus the width of the density fall-off. An experiment in the Wisconsin levitated toroidal octupole, using vector E x vector B drifts alone, demonstrates divertor-like behavior, including 70% reduction of plasma density near the wall and 40% reduction of plasma flux to the wall, with no adverse effects on confinement of the main plasma

Rotations with Rodrigues' vector

International Nuclear Information System (INIS)

Pina, E

2011-01-01

The rotational dynamics was studied from the point of view of Rodrigues' vector. This vector is defined here by its connection with other forms of parametrization of the rotation matrix. The rotation matrix was expressed in terms of this vector. The angular velocity was computed using the components of Rodrigues' vector as coordinates. It appears to be a fundamental matrix that is used to express the components of the angular velocity, the rotation matrix and the angular momentum vector. The Hamiltonian formalism of rotational dynamics in terms of this vector uses the same matrix. The quantization of the rotational dynamics is performed with simple rules if one uses Rodrigues' vector and similar formal expressions for the quantum operators that mimic the Hamiltonian classical dynamics.

Violation of vector dominance in the vector manifestation

International Nuclear Information System (INIS)

Sasaki, Chihiro

2003-01-01

The vector manifestation (VM) is a new pattern for realizing the chiral symmetry in QCD. In the VM, the massless vector meson becomes the chiral partner of pion at the critical point, in contrast with the restoration based on the linear sigma model. Including the intrinsic temperature dependences of the parameters of the hidden local symmetry (HLS) Lagrangian determined from the underlying QCD through the Wilsonian matching together with the hadronic thermal corrections, we present a new prediction of the VM on the direct photon-π-π coupling which measures the validity of the vector dominance (VD) of the electromagnetic form factor of the pion. We find that the VD is largely violated at the critical temperature, which indicates that the assumption of the VD made in several analysis on the dilepton spectra in hot matter may need to be weakened for consistently including the effect of the dropping mass of the vector meson. (author)

Design, development and evaluation of an online grading system for peeled pistachios equipped with machine vision technology and support vector machine

Directory of Open Access Journals (Sweden)

Hosein Nouri-Ahmadabadi

2017-12-01

Full Text Available In this study, an intelligent system based on combined machine vision (MV and Support Vector Machine (SVM was developed for sorting of peeled pistachio kernels and shells. The system was composed of conveyor belt, lighting box, camera, processing unit and sorting unit. A color CCD camera was used to capture images. The images were digitalized by a capture card and transferred to a personal computer for further analysis. Initially, images were converted from RGB color space to HSV color ones. For segmentation of the acquired images, H-component in the HSV color space and Otsu thresholding method were applied. A feature vector containing 30 color features was extracted from the captured images. A feature selection method based on sensitivity analysis was carried out to select superior features. The selected features were presented to SVM classifier. Various SVM models having a different kernel function were developed and tested. The SVM model having cubic polynomial kernel function and 38 support vectors achieved the best accuracy (99.17% and then was selected to use in online decision-making unit of the system. By launching the online system, it was found that limiting factors of the system capacity were related to the hardware parts of the system (conveyor belt and pneumatic valves used in the sorting unit. The limiting factors led to a distance of 8 mm between the samples. The overall accuracy and capacity of the sorter were obtained 94.33% and 22.74 kg/h, respectively. Keywords: Pistachio kernel, Sorting, Machine vision, Sensitivity analysis, Support vector machine

Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9.

Directory of Open Access Journals (Sweden)

Kazuhisa Honma

Full Text Available Mouse artificial chromosome (MAC vectors have several advantages as gene delivery vectors, such as stable and independent maintenance in host cells without integration, transferability from donor cells to recipient cells via microcell-mediated chromosome transfer (MMCT, and the potential for loading a megabase-sized DNA fragment. Previously, a MAC containing a multi-integrase platform (MI-MAC was developed to facilitate the transfer of multiple genes into desired cells. Although the MI system can theoretically hold five gene-loading vectors (GLVs, there are a limited number of drugs available for the selection of multiple-GLV integration. To overcome this issue, we attempted to knock out and reuse drug resistance genes (DRGs using the CRISPR-Cas9 system. In this study, we developed new methods for multiple-GLV integration. As a proof of concept, we introduced five GLVs in the MI-MAC by these methods, in which each GLV contained a gene encoding a fluorescent or luminescent protein (EGFP, mCherry, BFP, Eluc, and Cluc. Genes of interest (GOI on the MI-MAC were expressed stably and functionally without silencing in the host cells. Furthermore, the MI-MAC carrying five GLVs was transferred to other cells by MMCT, and the resultant recipient cells exhibited all five fluorescence/luminescence signals. Thus, the MI-MAC was successfully used as a multiple-GLV integration vector using the CRISPR-Cas9 system. The MI-MAC employing these methods may resolve bottlenecks in developing multiple-gene humanized models, multiple-gene monitoring models, disease models, reprogramming, and inducible gene expression systems.

Measurement of K/sub NN/, K/sub LL/ in p vector d → n vector X and p vector 9Be → n vector X at 800 MeV

International Nuclear Information System (INIS)

Riley, P.J.; Hollas, C.L.; Newsom, C.R.

1980-01-01

The spin transfer parameters, K/sub NN/ and K/sub LL/, have been measured in p vector d → n vector X and p vector 9 Be → n vector X at 0 0 and 800 MeV. The rather large values of K/sub LL/ demonstrate that this transfer mechanism will provide a useful source of polarized neutrons at LAMPF energies

Raster images vectorization system

OpenAIRE

Genytė, Jurgita

2006-01-01

The problem of raster images vectorization was analyzed and researched in this work. Existing vectorization systems are quite expensive, the results are inaccurate, and the manual vectorization of a large number of drafts is impossible. That‘s why our goal was to design and develop a new raster images vectorization system using our suggested automatic vectorization algorithm and the way to record results in a new universal vectorial file format. The work consists of these main parts: analysis...

Vectorization of phase space Monte Carlo code in FACOM vector processor VP-200

International Nuclear Information System (INIS)

Miura, Kenichi

1986-01-01

This paper describes the vectorization techniques for Monte Carlo codes in Fujitsu's Vector Processor System. The phase space Monte Carlo code FOWL is selected as a benchmark, and scalar and vector performances are compared. The vectorized kernel Monte Carlo routine which contains heavily nested IF tests runs up to 7.9 times faster in vector mode than in scalar mode. The overall performance improvement of the vectorized FOWL code over the original scalar code reaches 3.3. The results of this study strongly indicate that supercomputer can be a powerful tool for Monte Carlo simulations in high energy physics. (Auth.)

Vector grammars and PN machines

Institute of Scientific and Technical Information of China (English)

蒋昌俊

1996-01-01

The concept of vector grammars under the string semantic is introduced.The dass of vector grammars is given,which is similar to the dass of Chomsky grammars.The regular vector grammar is divided further.The strong and weak relation between the vector grammar and scalar grammar is discussed,so the spectrum system graph of scalar and vector grammars is made.The equivalent relation between the regular vector grammar and Petri nets (also called PN machine) is pointed.The hybrid PN machine is introduced,and its language is proved equivalent to the language of the context-free vector grammar.So the perfect relation structure between vector grammars and PN machines is formed.

Vector velocimeter

DEFF Research Database (Denmark)

2012-01-01

The present invention relates to a compact, reliable and low-cost vector velocimeter for example for determining velocities of particles suspended in a gas or fluid flow, or for determining velocity, displacement, rotation, or vibration of a solid surface, the vector velocimeter comprising a laser...

Cloning vector

Science.gov (United States)

Guilfoyle, Richard A.; Smith, Lloyd M.

1994-01-01

A vector comprising a filamentous phage sequence containing a first copy of filamentous phage gene X and other sequences necessary for the phage to propagate is disclosed. The vector also contains a second copy of filamentous phage gene X downstream from a promoter capable of promoting transcription in a bacterial host. In a preferred form of the present invention, the filamentous phage is M13 and the vector additionally includes a restriction endonuclease site located in such a manner as to substantially inactivate the second gene X when a DNA sequence is inserted into the restriction site.

Cloning vector

Science.gov (United States)

Guilfoyle, R.A.; Smith, L.M.

1994-12-27

A vector comprising a filamentous phage sequence containing a first copy of filamentous phage gene X and other sequences necessary for the phage to propagate is disclosed. The vector also contains a second copy of filamentous phage gene X downstream from a promoter capable of promoting transcription in a bacterial host. In a preferred form of the present invention, the filamentous phage is M13 and the vector additionally includes a restriction endonuclease site located in such a manner as to substantially inactivate the second gene X when a DNA sequence is inserted into the restriction site. 2 figures.

Vector 33: A reduce program for vector algebra and calculus in orthogonal curvilinear coordinates

Science.gov (United States)

Harper, David

1989-06-01

This paper describes a package with enables REDUCE 3.3 to perform algebra and calculus operations upon vectors. Basic algebraic operations between vectors and between scalars and vectors are provided, including scalar (dot) product and vector (cross) product. The vector differential operators curl, divergence, gradient and Laplacian are also defined, and are valid in any orthogonal curvilinear coordinate system. The package is written in RLISP to allow algebra and calculus to be performed using notation identical to that for operations. Scalars and vectors can be mixed quite freely in the same expression. The package will be of interest to mathematicians, engineers and scientists who need to perform vector calculations in orthogonal curvilinear coordinates.

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation

Science.gov (United States)

van Nierop, Pim; Vormer, Tinke L.; Foijer, Floris; Verheij, Joanne; Lodder, Johannes C.; Andersen, Jesper B.; Mansvelder, Huibert D.; te Riele, Hein

2018-01-01

To identify coding and non-coding suppressor genes of anchorage-independent proliferation by efficient loss-of-function screening, we have developed a method for enzymatic production of low complexity shRNA libraries from subtracted transcriptomes. We produced and screened two LEGO (Low-complexity by Enrichment for Genes shut Off) shRNA libraries that were enriched for shRNA vectors targeting coding and non-coding polyadenylated transcripts that were reduced in transformed Mouse Embryonic Fibroblasts (MEFs). The LEGO shRNA libraries included ~25 shRNA vectors per transcript which limited off-target artifacts. Our method identified 79 coding and non-coding suppressor transcripts. We found that taurine-responsive GABAA receptor subunits, including GABRA5 and GABRB3, were induced during the arrest of non-transformed anchor-deprived MEFs and prevented anchorless proliferation. We show that taurine activates chloride currents through GABAA receptors on MEFs, causing seclusion of cell volume in large membrane protrusions. Volume seclusion from cells by taurine correlated with reduced proliferation and, conversely, suppression of this pathway allowed anchorage-independent proliferation. In human cholangiocarcinomas, we found that several proteins involved in taurine signaling via GABAA receptors were repressed. Low GABRA5 expression typified hyperproliferative tumors, and loss of taurine signaling correlated with reduced patient survival, suggesting this tumor suppressive mechanism operates in vivo. PMID:29787571

Probing deformed orbitals with vector A( vector e, e' N)B reactions

International Nuclear Information System (INIS)

Garrido, E.; Caballero, J.A.; Moya de Guerra, E.; Sarriguren, P.; Udias, J.M.

1995-01-01

We present results for response functions and asymmetries in the nuclear reactions 37 vector Ar( vector e, e' n) 36 Ar and 37 vector K( vector e,e' p) 36 Ar at quasifree kinematics. We compare PWIA results obtained using deformed HF wave functions with PWIA and DWIA results obtained assuming a spherical mean field. We show that the complex structure of the deformed orbitals can be probed by coincidence measurements with polarized beam and targets. ((orig.))

O leigo e o suporte básico de vida El lego y el soporte básico de vida Laypeople and basic life support

Directory of Open Access Journals (Sweden)

Aline Maino Pergola

2009-06-01

Full Text Available A capacitação do leigo para o atendimento precoce em situações de emergência e instituição do suporte básico de vida (SBV é fundamental para salvar vidas e prevenir seqüelas. O objetivo foi identificar o conhecimento dos leigos sobre SBV. Utililizou-se entrevista estruturada em linguagem não-técnica. A amostra compreendeu 385 sujeitos, a maioria (57,1% do sexo feminino com ensino médio completo e superior incompleto (53,7%. Verificou-se apenas 9,9% conhecem a manobra de respiração boca-a-boca; 84,2% conhecem a técnica de compressão torácica externa (CTE, e destes, 79,9% sabem sua finalidade. Apenas 14,5% sabem posicionar a vítima para realizar a CTE; 82,4% referem uma freqüência menor que 60 CTE/minuto. Por não apresentarem adequada informação e fundamentação das etapas do SBV, os leigos podem prestar atendimento incorreto à vítima de emergência, acarretando prejuízos à reanimação.La capacitación del lego para la atención precoz en situaciones de emergencia e aplicación del soporte básico de vida (SBV es fundamental para salvar vidas y prevenir secuelas. El objetivo fue identificar el conocimiento de los legos sobre SBV. Se utililizó la entrevista estructurada en un lenguague no técnico. La muestra comprendió 385 sujetos, la mayoría (57,1% del sexo femenino con enseñanza media completa y superior incompleta (53,7%; Los que conocen la maniobra de respiración boca a boca son apenas 9,9%; 84,2% conocen la técnica de compresión toráxica externa (CTE y de estos, 79,9% saben su finalidad. Apenas 14,5% saben posicionar a la víctima para realizar la CTE, 82,4% refieren una frecuencia menor que 60 CTE/minuto. Por no presentar adecuada información y fundamentos de las etapas del SBV, los legos pueden prestar una atención incorrecta a la víctima de emergencia, ocasionando perjuicios en la reanimación.Training laypeople to give first aid in emergency situations and offer basic life support (BLS is crucial

Multi-perspective views of students’ difficulties with one-dimensional vector and two-dimensional vector

Science.gov (United States)

Fauzi, Ahmad; Ratna Kawuri, Kunthi; Pratiwi, Retno

2017-01-01

Researchers of students’ conceptual change usually collects data from written tests and interviews. Moreover, reports of conceptual change often simply refer to changes in concepts, such as on a test, without any identification of the learning processes that have taken place. Research has shown that students have difficulties with vectors in university introductory physics courses and high school physics courses. In this study, we intended to explore students’ understanding of one-dimensional and two-dimensional vector in multi perspective views. In this research, we explore students’ understanding through test perspective and interviews perspective. Our research study adopted the mixed-methodology design. The participants of this research were sixty students of third semester of physics education department. The data of this research were collected by testand interviews. In this study, we divided the students’ understanding of one-dimensional vector and two-dimensional vector in two categories, namely vector skills of the addition of one-dimensionaland two-dimensional vector and the relation between vector skills and conceptual understanding. From the investigation, only 44% of students provided correct answer for vector skills of the addition of one-dimensional and two-dimensional vector and only 27% students provided correct answer for the relation between vector skills and conceptual understanding.

Comparison of Customer Preference for Bulk Material Handling Equipment through Fuzzy-AHP Approach

Science.gov (United States)

Sen, Kingshuk; Ghosh, Surojit; Sarkar, Bijan

2017-06-01

In the present study, customer's perception has played one of the important roles for selection of the exact equipment out of available alternatives. The present study is dealt with the method of optimization of selection criteria of a material handling equipment, based on the technical specifications considered to be available at the user end. In this work, the needs of customers have been identified and prioritized, that lead to the selection of number of criteria, which have direct effect upon the performance of the equipment. To check the consistency of selection criteria, first of all an AHP based methodology is adopted with the identified criteria and available product categories, based upon which, the judgments of the users are defined to derive the priority scales. Such judgments expressed the relative strength or intensity of the impact of the elements of the hierarchy. Subsequently, all the alternatives have ranked for each identified criteria with subsequent constitution of weighted matrices. The same has been compared with the normalized values of approximate selling prices of the equipments to determine individual cost-benefit ratio. Based on the cost-benefit ratio, the equipment is ranked. With same conditions, the study is obtained again with a Fuzzy AHP concept, where a fuzzy linguistic approach has reduced the amount of uncertainty in decision making, caused by conventional AHP due to lack of deterministic approach. The priority vectors of category and criteria are determined separately and multiplied to obtain composite score. Subsequently, the average of fuzzy weights was determined and the preferences of equipment are ranked.

Custodial vector model

Science.gov (United States)

Becciolini, Diego; Franzosi, Diogo Buarque; Foadi, Roshan; Frandsen, Mads T.; Hapola, Tuomas; Sannino, Francesco

2015-07-01

We analyze the Large Hadron Collider (LHC) phenomenology of heavy vector resonances with a S U (2 )L×S U (2 )R spectral global symmetry. This symmetry partially protects the electroweak S parameter from large contributions of the vector resonances. The resulting custodial vector model spectrum and interactions with the standard model fields lead to distinct signatures at the LHC in the diboson, dilepton, and associated Higgs channels.

Vector Differential Calculus

OpenAIRE

HITZER, Eckhard MS

2002-01-01

This paper treats the fundamentals of the vector differential calculus part of universal geometric calculus. Geometric calculus simplifies and unifies the structure and notation of mathematics for all of science and engineering, and for technological applications. In order to make the treatment self-contained, I first compile all important geometric algebra relationships,which are necesssary for vector differential calculus. Then differentiation by vectors is introduced and a host of major ve...

Vectorization, parallelization and porting of nuclear codes. Vectorization and parallelization. Progress report fiscal 1999

Energy Technology Data Exchange (ETDEWEB)

Adachi, Masaaki; Ogasawara, Shinobu; Kume, Etsuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Ishizuki, Shigeru; Nemoto, Toshiyuki; Kawasaki, Nobuo; Kawai, Wataru [Fujitsu Ltd., Tokyo (Japan); Yatake, Yo-ichi [Hitachi Ltd., Tokyo (Japan)

2001-02-01

Several computer codes in the nuclear field have been vectorized, parallelized and trans-ported on the FUJITSU VPP500 system, the AP3000 system, the SX-4 system and the Paragon system at Center for Promotion of Computational Science and Engineering in Japan Atomic Energy Research Institute. We dealt with 18 codes in fiscal 1999. These results are reported in 3 parts, i.e., the vectorization and the parallelization part on vector processors, the parallelization part on scalar processors and the porting part. In this report, we describe the vectorization and parallelization on vector processors. In this vectorization and parallelization on vector processors part, the vectorization of Relativistic Molecular Orbital Calculation code RSCAT, a microscopic transport code for high energy nuclear collisions code JAM, three-dimensional non-steady thermal-fluid analysis code STREAM, Relativistic Density Functional Theory code RDFT and High Speed Three-Dimensional Nodal Diffusion code MOSRA-Light on the VPP500 system and the SX-4 system are described. (author)

Elliptic-symmetry vector optical fields.

Science.gov (United States)

Pan, Yue; Li, Yongnan; Li, Si-Min; Ren, Zhi-Cheng; Kong, Ling-Jun; Tu, Chenghou; Wang, Hui-Tian

2014-08-11

We present in principle and demonstrate experimentally a new kind of vector fields: elliptic-symmetry vector optical fields. This is a significant development in vector fields, as this breaks the cylindrical symmetry and enriches the family of vector fields. Due to the presence of an additional degrees of freedom, which is the interval between the foci in the elliptic coordinate system, the elliptic-symmetry vector fields are more flexible than the cylindrical vector fields for controlling the spatial structure of polarization and for engineering the focusing fields. The elliptic-symmetry vector fields can find many specific applications from optical trapping to optical machining and so on.

Chikungunya Virus–Vector Interactions

Directory of Open Access Journals (Sweden)

Lark L. Coffey

2014-11-01

Full Text Available Chikungunya virus (CHIKV is a mosquito-borne alphavirus that causes chikungunya fever, a severe, debilitating disease that often produces chronic arthralgia. Since 2004, CHIKV has emerged in Africa, Indian Ocean islands, Asia, Europe, and the Americas, causing millions of human infections. Central to understanding CHIKV emergence is knowledge of the natural ecology of transmission and vector infection dynamics. This review presents current understanding of CHIKV infection dynamics in mosquito vectors and its relationship to human disease emergence. The following topics are reviewed: CHIKV infection and vector life history traits including transmission cycles, genetic origins, distribution, emergence and spread, dispersal, vector competence, vector immunity and microbial interactions, and co-infection by CHIKV and other arboviruses. The genetics of vector susceptibility and host range changes, population heterogeneity and selection for the fittest viral genomes, dual host cycling and its impact on CHIKV adaptation, viral bottlenecks and intrahost diversity, and adaptive constraints on CHIKV evolution are also discussed. The potential for CHIKV re-emergence and expansion into new areas and prospects for prevention via vector control are also briefly reviewed.

APLIKASI JARINGAN KOMUNIKASI ROBOT MULTIHOP TERDISTRIBUSI PADA LINGKUNGAN STATIS TERBATAS: IMPLEMENTASI, SIMULASI DAN ANALISIS PADA KASUS ROBOT LEGO MINDSTORM NXT

Directory of Open Access Journals (Sweden)

Wisnu Jatmiko

2012-05-01

Full Text Available Paper ini akan membahas tahap awal (prototipe pengembangan jaringan komunikasi-robot multihop terdistribusi, yaitu suatu aplikasi yang diharapkan dapat dimanfaatkan pada lingkungan yang minim infrastruktur dan fasilitas komunikasi. Pada bagian awal paper disebutkan kondisi yang dapat menerapkan aplikasi jaringan komunikasi multihop ini, yaitu pada daerah bencana alam yang mengalami kerusakan sarana komunikasi, pada daerah terpencil karena faktor alam yang sulit untuk diadakan fasilitas komunikasi, ataupun daerah berbahaya untuk didatangi manusia ataupun kawasan konflik dan peperangan. Salah satu karakteristik yang diharapkan dari aplikasi ini adalah proses penyebaran informasi secara cepat dan mudah, bahkan walaupun tidak tersedia infrastruktur memadai sebelumnya. Selain itu, sistem ini bersifat terdistribusi sehingga diharapkan dapat memberikan beberapa keuntungan, baik saat diimplementasikan maupun kinerja di lapangan nantinya. Paper ini kemudian membahas pengembangan algoritma penyelesaian masalah, yang dilanjutkan dengan verifikasi dan analisis pada level simulasi perangkat lunak. Selanjutkan, algoritma ini diterapkan pada level simulasi perangkat keras dengan menggunakan modul robot Lego Mindstorm NXT. Untuk penyederhanaan masalah, pada tahap ini lingkungan yang digunakan masih bersifat statis dan terbatas sebagai salah satu asumsi.

Extended vector-tensor theories

Energy Technology Data Exchange (ETDEWEB)

Kimura, Rampei; Naruko, Atsushi; Yoshida, Daisuke, E-mail: rampei@th.phys.titech.ac.jp, E-mail: naruko@th.phys.titech.ac.jp, E-mail: yoshida@th.phys.titech.ac.jp [Department of Physics, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan)

2017-01-01

Recently, several extensions of massive vector theory in curved space-time have been proposed in many literatures. In this paper, we consider the most general vector-tensor theories that contain up to two derivatives with respect to metric and vector field. By imposing a degeneracy condition of the Lagrangian in the context of ADM decomposition of space-time to eliminate an unwanted mode, we construct a new class of massive vector theories where five degrees of freedom can propagate, corresponding to three for massive vector modes and two for massless tensor modes. We find that the generalized Proca and the beyond generalized Proca theories up to the quartic Lagrangian, which should be included in this formulation, are degenerate theories even in curved space-time. Finally, introducing new metric and vector field transformations, we investigate the properties of thus obtained theories under such transformations.

Hyperbolic-symmetry vector fields.

Science.gov (United States)

Gao, Xu-Zhen; Pan, Yue; Cai, Meng-Qiang; Li, Yongnan; Tu, Chenghou; Wang, Hui-Tian

2015-12-14

We present and construct a new kind of orthogonal coordinate system, hyperbolic coordinate system. We present and design a new kind of local linearly polarized vector fields, which is defined as the hyperbolic-symmetry vector fields because the points with the same polarization form a series of hyperbolae. We experimentally demonstrate the generation of such a kind of hyperbolic-symmetry vector optical fields. In particular, we also study the modified hyperbolic-symmetry vector optical fields with the twofold and fourfold symmetric states of polarization when introducing the mirror symmetry. The tight focusing behaviors of these vector fields are also investigated. In addition, we also fabricate micro-structures on the K9 glass surfaces by several tightly focused (modified) hyperbolic-symmetry vector fields patterns, which demonstrate that the simulated tightly focused fields are in good agreement with the fabricated micro-structures.

Supergravity inspired vector curvaton

International Nuclear Information System (INIS)

Dimopoulos, Konstantinos

2007-01-01

It is investigated whether a massive Abelian vector field, whose gauge kinetic function is growing during inflation, can be responsible for the generation of the curvature perturbation in the Universe. Particle production is studied and it is shown that the vector field can obtain a scale-invariant superhorizon spectrum of perturbations with a reasonable choice of kinetic function. After inflation the vector field begins coherent oscillations, during which it corresponds to pressureless isotropic matter. When the vector field dominates the Universe, its perturbations give rise to the observed curvature perturbation following the curvaton scenario. It is found that this is possible if, after the end of inflation, the mass of the vector field increases at a phase transition at temperature of order 1 TeV or lower. Inhomogeneous reheating, whereby the vector field modulates the decay rate of the inflaton, is also studied

Embedded vision equipment of industrial robot for inline detection of product errors by clustering–classification algorithms

Directory of Open Access Journals (Sweden)

Kamil Zidek

2016-10-01

Full Text Available The article deals with the design of embedded vision equipment of industrial robots for inline diagnosis of product error during manipulation process. The vision equipment can be attached to the end effector of robots or manipulators, and it provides an image snapshot of part surface before grasp, searches for error during manipulation, and separates products with error from the next operation of manufacturing. The new approach is a methodology based on machine teaching for the automated identification, localization, and diagnosis of systematic errors in products of high-volume production. To achieve this, we used two main data mining algorithms: clustering for accumulation of similar errors and classification methods for the prediction of any new error to proposed class. The presented methodology consists of three separate processing levels: image acquisition for fail parameterization, data clustering for categorizing errors to separate classes, and new pattern prediction with a proposed class model. We choose main representatives of clustering algorithms, for example, K-mean from quantization of vectors, fast library for approximate nearest neighbor from hierarchical clustering, and density-based spatial clustering of applications with noise from algorithm based on the density of the data. For machine learning, we selected six major algorithms of classification: support vector machines, normal Bayesian classifier, K-nearest neighbor, gradient boosted trees, random trees, and neural networks. The selected algorithms were compared for speed and reliability and tested on two platforms: desktop-based computer system and embedded system based on System on Chip (SoC with vision equipment.

Constraining vectors and axial-vectors in walking technicolour by a holographic principle

DEFF Research Database (Denmark)

D. Dietrich, Dennis; Kouvaris, Christoforos

2008-01-01

We use a holographic principle to study the low-energy spectrum of walking technicolour models. In particular, we predict the masses of the axial vectors as well as the decay constants of vectors and axial vectors as functions of the mass of the techni-rho. Given that there are very few...

Recommendation on vectors and vector-transmitted diseases

OpenAIRE

Netherlands Food and Consumer Product Safety Authority

2009-01-01

In view of their increasing risk of introduction and their possible implications in causing major disease outbreaks, vectors, as well as vector-transmitted diseases like dengue, West Nile disease, Lyme disease and bluetongue need to be recognised as a threat to public and animal health and to the economy, also in the Netherlands. There has been an increase in the incidence of these diseases in the past two to three decades. Climate changes and changes in the use of land, water managemen...

Gauge anomaly with vector and axial-vector fields in 6D curved space

Science.gov (United States)

Yajima, Satoshi; Eguchi, Kohei; Fukuda, Makoto; Oka, Tomonori

2018-03-01

Imposing the conservation equation of the vector current for a fermion of spin 1/2 at the quantum level, a gauge anomaly for the fermion coupling with non-Abelian vector and axial-vector fields in 6D curved space is expressed in tensorial form. The anomaly consists of terms that resemble the chiral U(1) anomaly and the commutator terms that disappear if the axial-vector field is Abelian.

Vector manifestation and violation of vector dominance in hot matter

International Nuclear Information System (INIS)

Harada, Masayasu; Sasaki, Chihiro

2004-01-01

We show the details of the calculation of the hadronic thermal corrections to the two-point functions in the effective field theory of QCD for pions and vector mesons based on the hidden local symmetry (HLS) in hot matter using the background field gauge. We study the temperature dependence of the pion velocity in the low-temperature region determined from the hadronic thermal corrections, and show that, due to the presence of the dynamical vector meson, the pion velocity is smaller than the speed of the light already at one-loop level, in contrast to the result obtained in the ordinary chiral perturbation theory including only the pion at one-loop. Including the intrinsic temperature dependences of the parameters of the HLS Lagrangian determined from the underlying QCD through the Wilsonian matching, we show how the vector manifestation (VM), in which the massless vector meson becomes the chiral partner of pion, is realized at the critical temperature. We present a new prediction of the VM on the direct photon-π-π coupling which measures the validity of the vector dominance (VD) of the electromagnetic form factor of the pion: we find that the VD is largely violated at the critical temperature, which indicates that the assumption of the VD made in several analyses on the dilepton spectra in hot matter may need to be weakened for consistently including the effect of the dropping mass of the vector meson

Heavy Scalar, Vector, and Axial-Vector Mesons in Hot and Dense Nuclear Medium

Directory of Open Access Journals (Sweden)

Arvind Kumar

2014-01-01

Full Text Available In this work we shall investigate the mass modifications of scalar mesons (D0; B0, vector mesons (D*; B*, and axial-vector mesons (D1; B1 at finite density and temperature of the nuclear medium. The above mesons are modified in the nuclear medium through the modification of quark and gluon condensates. We will find the medium modification of quark and gluon condensates within chiral SU(3 model through the medium modification of scalar-isoscalar fields σ and ζ at finite density and temperature. These medium modified quark and gluon condensates will further be used through QCD sum rules for the evaluation of in-medium properties of the above mentioned scalar, vector, and axial vector mesons. We will also discuss the effects of density and temperature of the nuclear medium on the scattering lengths of the above scalar, vector, and axial-vector mesons. The study of the medium modifications of the above mesons may be helpful for understanding their production rates in heavy-ion collision experiments. The results of present investigations of medium modifications of scalar, vector, and axial-vector mesons at finite density and temperature can be verified in the compressed baryonic matter (CBM experiment of FAIR facility at GSI, Germany.

Vector Fields on Product Manifolds

OpenAIRE

Kurz, Stefan

2011-01-01

This short report establishes some basic properties of smooth vector fields on product manifolds. The main results are: (i) On a product manifold there always exists a direct sum decomposition into horizontal and vertical vector fields. (ii) Horizontal and vertical vector fields are naturally isomorphic to smooth families of vector fields defined on the factors. Vector fields are regarded as derivations of the algebra of smooth functions.

Light scattering of rectangular slot antennas: parallel magnetic vector vs perpendicular electric vector

Science.gov (United States)

Lee, Dukhyung; Kim, Dai-Sik

2016-01-01

We study light scattering off rectangular slot nano antennas on a metal film varying incident polarization and incident angle, to examine which field vector of light is more important: electric vector perpendicular to, versus magnetic vector parallel to the long axis of the rectangle. While vector Babinet’s principle would prefer magnetic field along the long axis for optimizing slot antenna function, convention and intuition most often refer to the electric field perpendicular to it. Here, we demonstrate experimentally that in accordance with vector Babinet’s principle, the incident magnetic vector parallel to the long axis is the dominant component, with the perpendicular incident electric field making a small contribution of the factor of 1/|ε|, the reciprocal of the absolute value of the dielectric constant of the metal, owing to the non-perfectness of metals at optical frequencies.

Generalization of concurrence vectors

International Nuclear Information System (INIS)

Yu Changshui; Song Heshan

2004-01-01

In this Letter, based on the generalization of concurrence vectors for bipartite pure state with respect to employing tensor product of generators of the corresponding rotation groups, we generalize concurrence vectors to the case of mixed states; a new criterion of separability of multipartite pure states is given out, for which we define a concurrence vector; we generalize the vector to the case of multipartite mixed state and give out a good measure of free entanglement

Vector Network Coding Algorithms

OpenAIRE

Ebrahimi, Javad; Fragouli, Christina

2010-01-01

We develop new algebraic algorithms for scalar and vector network coding. In vector network coding, the source multicasts information by transmitting vectors of length L, while intermediate nodes process and combine their incoming packets by multiplying them with L x L coding matrices that play a similar role as coding c in scalar coding. Our algorithms for scalar network jointly optimize the employed field size while selecting the coding coefficients. Similarly, for vector coding, our algori...

Complex Polynomial Vector Fields

DEFF Research Database (Denmark)

Dias, Kealey

vector fields. Since the class of complex polynomial vector fields in the plane is natural to consider, it is remarkable that its study has only begun very recently. There are numerous fundamental questions that are still open, both in the general classification of these vector fields, the decomposition...... of parameter spaces into structurally stable domains, and a description of the bifurcations. For this reason, the talk will focus on these questions for complex polynomial vector fields.......The two branches of dynamical systems, continuous and discrete, correspond to the study of differential equations (vector fields) and iteration of mappings respectively. In holomorphic dynamics, the systems studied are restricted to those described by holomorphic (complex analytic) functions...

Validation of SplitVectors Encoding for Quantitative Visualization of Large-Magnitude-Range Vector Fields.

Science.gov (United States)

Henan Zhao; Bryant, Garnett W; Griffin, Wesley; Terrill, Judith E; Jian Chen

2017-06-01

We designed and evaluated SplitVectors, a new vector field display approach to help scientists perform new discrimination tasks on large-magnitude-range scientific data shown in three-dimensional (3D) visualization environments. SplitVectors uses scientific notation to display vector magnitude, thus improving legibility. We present an empirical study comparing the SplitVectors approach with three other approaches - direct linear representation, logarithmic, and text display commonly used in scientific visualizations. Twenty participants performed three domain analysis tasks: reading numerical values (a discrimination task), finding the ratio between values (a discrimination task), and finding the larger of two vectors (a pattern detection task). Participants used both mono and stereo conditions. Our results suggest the following: (1) SplitVectors improve accuracy by about 10 times compared to linear mapping and by four times to logarithmic in discrimination tasks; (2) SplitVectors have no significant differences from the textual display approach, but reduce cluttering in the scene; (3) SplitVectors and textual display are less sensitive to data scale than linear and logarithmic approaches; (4) using logarithmic can be problematic as participants' confidence was as high as directly reading from the textual display, but their accuracy was poor; and (5) Stereoscopy improved performance, especially in more challenging discrimination tasks.

Vectorization, parallelization and porting of nuclear codes (vectorization and parallelization). Progress report fiscal 1998

International Nuclear Information System (INIS)

Ishizuki, Shigeru; Kawai, Wataru; Nemoto, Toshiyuki; Ogasawara, Shinobu; Kume, Etsuo; Adachi, Masaaki; Kawasaki, Nobuo; Yatake, Yo-ichi

2000-03-01

Several computer codes in the nuclear field have been vectorized, parallelized and transported on the FUJITSU VPP500 system, the AP3000 system and the Paragon system at Center for Promotion of Computational Science and Engineering in Japan Atomic Energy Research Institute. We dealt with 12 codes in fiscal 1998. These results are reported in 3 parts, i.e., the vectorization and parallelization on vector processors part, the parallelization on scalar processors part and the porting part. In this report, we describe the vectorization and parallelization on vector processors. In this vectorization and parallelization on vector processors part, the vectorization of General Tokamak Circuit Simulation Program code GTCSP, the vectorization and parallelization of Molecular Dynamics NTV (n-particle, Temperature and Velocity) Simulation code MSP2, Eddy Current Analysis code EDDYCAL, Thermal Analysis Code for Test of Passive Cooling System by HENDEL T2 code THANPACST2 and MHD Equilibrium code SELENEJ on the VPP500 are described. In the parallelization on scalar processors part, the parallelization of Monte Carlo N-Particle Transport code MCNP4B2, Plasma Hydrodynamics code using Cubic Interpolated Propagation Method PHCIP and Vectorized Monte Carlo code (continuous energy model / multi-group model) MVP/GMVP on the Paragon are described. In the porting part, the porting of Monte Carlo N-Particle Transport code MCNP4B2 and Reactor Safety Analysis code RELAP5 on the AP3000 are described. (author)

Design of online monitoring and forecasting system for electrical equipment temperature of prefabricated substation based on WSN

Science.gov (United States)

Qi, Weiran; Miao, Hongxia; Miao, Xuejiao; Xiao, Xuanxuan; Yan, Kuo

2016-10-01

In order to ensure the safe and stable operation of the prefabricated substations, temperature sensing subsystem, temperature remote monitoring and management subsystem, forecast subsystem are designed in the paper. Wireless temperature sensing subsystem which consists of temperature sensor and MCU sends the electrical equipment temperature to the remote monitoring center by wireless sensor network. Remote monitoring center can realize the remote monitoring and prediction by monitoring and management subsystem and forecast subsystem. Real-time monitoring of power equipment temperature, history inquiry database, user management, password settings, etc., were achieved by monitoring and management subsystem. In temperature forecast subsystem, firstly, the chaos of the temperature data was verified and phase space is reconstructed. Then Support Vector Machine - Particle Swarm Optimization (SVM-PSO) was used to predict the temperature of the power equipment in prefabricated substations. The simulation results found that compared with the traditional methods SVM-PSO has higher prediction accuracy.

Equivalent Vectors

Science.gov (United States)

Levine, Robert

2004-01-01

The cross-product is a mathematical operation that is performed between two 3-dimensional vectors. The result is a vector that is orthogonal or perpendicular to both of them. Learning about this for the first time while taking Calculus-III, the class was taught that if AxB = AxC, it does not necessarily follow that B = C. This seemed baffling. The…

Speculative dynamic vectorization to assist static vectorization in a HW/SW co-designed environment

OpenAIRE

Kumar, R.; Martinez, A.; Gonzalez, A.

2013-01-01

Compiler based static vectorization is used widely to extract data level parallelism from computation intensive applications. Static vectorization is very effective in vectorizing traditional array based applications. However, compilers inability to reorder ambiguous memory references severely limits vectorization opportunities, especially in pointer rich applications. HW/SW co-designed processors provide an excellent opportunity to optimize the applications at runtime. The availability of dy...

Generation of equipment response spectrum considering equipment-structure interaction

International Nuclear Information System (INIS)

Lee, Sang Hoon; Yoo, Kwang Hoon

2005-01-01

Floor response spectra for dynamic response of subsystem such as equipment, or piping in nuclear power plant are usually generated without considering dynamic interaction between main structure and subsystem. Since the dynamic structural response generally has the narrow-banded shapes, the resulting floor response spectra developed for various locations in the structure usually have high spectral peak amplitudes in the narrow frequency bands corresponding to the natural frequencies of the structural system. The application of such spectra for design of subsystems often leads to excessive design conservatisms, especially when the equipment frequency and structure are at resonance condition. Thus, in order to provide a rational and realistic design input for dynamic analysis and design of equipment, dynamic equipment-structure interaction (ESI) should be considered in developing equipment response spectrum which is particularly important for equipment at the resonance condition. Many analytical methods have been proposed in the past for developing equipment response spectra considering ESI. However, most of these methods have not been adapted to the practical applications because of either the complexities or the lack of rigorousness of the methods. At one hand, mass ratio among the equipment and structure was used as an important parameter to obtain equipment response spectra. Similarly, Tseng has also proposed the analytical method for developing equipment response spectra using mass ratio in the frequency domain. This method is analytically rigorous and can be easily validated. It is based on the dynamic substructuring method as applied to the dynamic soil-structure interaction (SSI) analysis, and can relatively easily be implemented for practical applications without to change the current dynamic analysis and design practice for subsystems. The equipment response spectra derived in this study are also based on Tseng's proposed method

Vectorization at the KENO-IV code

International Nuclear Information System (INIS)

Asai, K.; Higuchi, K.; Katakura, J.

1986-01-01

The multigroup criticality safety code KENO-IV has been vectorized and tested on the FACOM VP-100 vector processor. At first, the vectorized KENO-IV on a scalar processor was slower than the original one by a factor of 1.4 because of the overhead introduced by vectorization. Making modifications of algorithms and techniques for vectorization, the vectorized version has become faster than the original one by a factor of 1.4 on the vector processor. For further speedup of the code, some improvements on compiler and hardware, especially on addition of Monte Carlo pipelines to the vector processor, are discussed

Reciprocity relationships in vector acoustics and their application to vector field calculations.

Science.gov (United States)

Deal, Thomas J; Smith, Kevin B

2017-08-01

The reciprocity equation commonly stated in underwater acoustics relates pressure fields and monopole sources. It is often used to predict the pressure measured by a hydrophone for multiple source locations by placing a source at the hydrophone location and calculating the field everywhere for that source. A similar equation that governs the orthogonal components of the particle velocity field is needed to enable this computational method to be used for acoustic vector sensors. This paper derives a general reciprocity equation that accounts for both monopole and dipole sources. This vector-scalar reciprocity equation can be used to calculate individual components of the received vector field by altering the source type used in the propagation calculation. This enables a propagation model to calculate the received vector field components for an arbitrary number of source locations with a single model run for each vector field component instead of requiring one model run for each source location. Application of the vector-scalar reciprocity principle is demonstrated with analytic solutions for a range-independent environment and with numerical solutions for a range-dependent environment using a parabolic equation model.

Vectors and their applications

CERN Document Server

Pettofrezzo, Anthony J

2005-01-01

Geared toward undergraduate students, this text illustrates the use of vectors as a mathematical tool in plane synthetic geometry, plane and spherical trigonometry, and analytic geometry of two- and three-dimensional space. Its rigorous development includes a complete treatment of the algebra of vectors in the first two chapters.Among the text's outstanding features are numbered definitions and theorems in the development of vector algebra, which appear in italics for easy reference. Most of the theorems include proofs, and coordinate position vectors receive an in-depth treatment. Key concept

9 CFR 590.502 - Equipment and utensils; PCB-containing equipment.

Science.gov (United States)

2010-01-01

... Sanitary Standards and accepted practices currently in effect for such equipment. (c) New or replacement equipment or machinery (including any replacement parts) brought onto the premises of any official plant... equipment and machinery, and any replacement parts for such equipment and machinery. Totally enclosed...

Convexity and Marginal Vectors

NARCIS (Netherlands)

van Velzen, S.; Hamers, H.J.M.; Norde, H.W.

2002-01-01

In this paper we construct sets of marginal vectors of a TU game with the property that if the marginal vectors from these sets are core elements, then the game is convex.This approach leads to new upperbounds on the number of marginal vectors needed to characterize convexity.An other result is that

Integrating Transgenic Vector Manipulation with Clinical Interventions to Manage Vector-Borne Diseases.

Directory of Open Access Journals (Sweden)

Kenichi W Okamoto

2016-03-01

Full Text Available Many vector-borne diseases lack effective vaccines and medications, and the limitations of traditional vector control have inspired novel approaches based on using genetic engineering to manipulate vector populations and thereby reduce transmission. Yet both the short- and long-term epidemiological effects of these transgenic strategies are highly uncertain. If neither vaccines, medications, nor transgenic strategies can by themselves suffice for managing vector-borne diseases, integrating these approaches becomes key. Here we develop a framework to evaluate how clinical interventions (i.e., vaccination and medication can be integrated with transgenic vector manipulation strategies to prevent disease invasion and reduce disease incidence. We show that the ability of clinical interventions to accelerate disease suppression can depend on the nature of the transgenic manipulation deployed (e.g., whether vector population reduction or replacement is attempted. We find that making a specific, individual strategy highly effective may not be necessary for attaining public-health objectives, provided suitable combinations can be adopted. However, we show how combining only partially effective antimicrobial drugs or vaccination with transgenic vector manipulations that merely temporarily lower vector competence can amplify disease resurgence following transient suppression. Thus, transgenic vector manipulation that cannot be sustained can have adverse consequences-consequences which ineffective clinical interventions can at best only mitigate, and at worst temporarily exacerbate. This result, which arises from differences between the time scale on which the interventions affect disease dynamics and the time scale of host population dynamics, highlights the importance of accounting for the potential delay in the effects of deploying public health strategies on long-term disease incidence. We find that for systems at the disease-endemic equilibrium, even

Complex Polynomial Vector Fields

DEFF Research Database (Denmark)

The two branches of dynamical systems, continuous and discrete, correspond to the study of differential equations (vector fields) and iteration of mappings respectively. In holomorphic dynamics, the systems studied are restricted to those described by holomorphic (complex analytic) functions...... or meromorphic (allowing poles as singularities) functions. There already exists a well-developed theory for iterative holomorphic dynamical systems, and successful relations found between iteration theory and flows of vector fields have been one of the main motivations for the recent interest in holomorphic...... vector fields. Since the class of complex polynomial vector fields in the plane is natural to consider, it is remarkable that its study has only begun very recently. There are numerous fundamental questions that are still open, both in the general classification of these vector fields, the decomposition...

Equipment considerations

International Nuclear Information System (INIS)

Anon.

1992-01-01

Trace or ultratrace analyses require that the HPLC equipment used, including the detector, be optimal for such determinations. HPLC detectors are discussed at length in Chapter 4; discussion here is limited to the rest of the equipment. In general, commercial equipment is adequate for trace analysis; however, as the authors approach ultratrace analysis, it becomes very important to examine the equipment thoroughly and optimize it, where possible. For this reason they will review the equipment commonly used in HPLC and discuss the optimization steps. Detectability in HPLC is influenced by two factors (1): (a) baseline noise or other interferences that lead to errors in assigning the baseline absorbance; (b) peak width. 87 refs

Vector financial rogue waves

International Nuclear Information System (INIS)

Yan, Zhenya

2011-01-01

The coupled nonlinear volatility and option pricing model presented recently by Ivancevic is investigated, which generates a leverage effect, i.e., stock volatility is (negatively) correlated to stock returns, and can be regarded as a coupled nonlinear wave alternative of the Black–Scholes option pricing model. In this Letter, we analytically propose vector financial rogue waves of the coupled nonlinear volatility and option pricing model without an embedded w-learning. Moreover, we exhibit their dynamical behaviors for chosen different parameters. The vector financial rogue wave (rogon) solutions may be used to describe the possible physical mechanisms for the rogue wave phenomena and to further excite the possibility of relative researches and potential applications of vector rogue waves in the financial markets and other related fields. -- Highlights: ► We investigate the coupled nonlinear volatility and option pricing model. ► We analytically present vector financial rogue waves. ► The vector financial rogue waves may be used to describe the extreme events in financial markets. ► This results may excite the relative researches and potential applications of vector rogue waves.

Video Vectorization via Tetrahedral Remeshing.

Science.gov (United States)

Wang, Chuan; Zhu, Jie; Guo, Yanwen; Wang, Wenping

2017-02-09

We present a video vectorization method that generates a video in vector representation from an input video in raster representation. A vector-based video representation offers the benefits of vector graphics, such as compactness and scalability. The vector video we generate is represented by a simplified tetrahedral control mesh over the spatial-temporal video volume, with color attributes defined at the mesh vertices. We present novel techniques for simplification and subdivision of a tetrahedral mesh to achieve high simplification ratio while preserving features and ensuring color fidelity. From an input raster video, our method is capable of generating a compact video in vector representation that allows a faithful reconstruction with low reconstruction errors.

Selection vector filter framework

Science.gov (United States)

Lukac, Rastislav; Plataniotis, Konstantinos N.; Smolka, Bogdan; Venetsanopoulos, Anastasios N.

2003-10-01

We provide a unified framework of nonlinear vector techniques outputting the lowest ranked vector. The proposed framework constitutes a generalized filter class for multichannel signal processing. A new class of nonlinear selection filters are based on the robust order-statistic theory and the minimization of the weighted distance function to other input samples. The proposed method can be designed to perform a variety of filtering operations including previously developed filtering techniques such as vector median, basic vector directional filter, directional distance filter, weighted vector median filters and weighted directional filters. A wide range of filtering operations is guaranteed by the filter structure with two independent weight vectors for angular and distance domains of the vector space. In order to adapt the filter parameters to varying signal and noise statistics, we provide also the generalized optimization algorithms taking the advantage of the weighted median filters and the relationship between standard median filter and vector median filter. Thus, we can deal with both statistical and deterministic aspects of the filter design process. It will be shown that the proposed method holds the required properties such as the capability of modelling the underlying system in the application at hand, the robustness with respect to errors in the model of underlying system, the availability of the training procedure and finally, the simplicity of filter representation, analysis, design and implementation. Simulation studies also indicate that the new filters are computationally attractive and have excellent performance in environments corrupted by bit errors and impulsive noise.

Medical Issues: Equipment

Science.gov (United States)

... Information Packets Equipment Pool Living With SMA Medical Issues Palliative Breathing Orthopedics Nutrition Equipment Daily Life At ... curesma.org > support & care > living with sma > medical issues > equipment Equipment Individuals with SMA often require a ...

Symbolic computer vector analysis

Science.gov (United States)

Stoutemyer, D. R.

1977-01-01

A MACSYMA program is described which performs symbolic vector algebra and vector calculus. The program can combine and simplify symbolic expressions including dot products and cross products, together with the gradient, divergence, curl, and Laplacian operators. The distribution of these operators over sums or products is under user control, as are various other expansions, including expansion into components in any specific orthogonal coordinate system. There is also a capability for deriving the scalar or vector potential of a vector field. Examples include derivation of the partial differential equations describing fluid flow and magnetohydrodynamics, for 12 different classic orthogonal curvilinear coordinate systems.

Vector continued fractions using a generalized inverse

International Nuclear Information System (INIS)

Haydock, Roger; Nex, C M M; Wexler, Geoffrey

2004-01-01

A real vector space combined with an inverse (involution) for vectors is sufficient to define a vector continued fraction whose parameters consist of vector shifts and changes of scale. The choice of sign for different components of the vector inverse permits construction of vector analogues of the Jacobi continued fraction. These vector Jacobi fractions are related to vector and scalar-valued polynomial functions of the vectors, which satisfy recurrence relations similar to those of orthogonal polynomials. The vector Jacobi fraction has strong convergence properties which are demonstrated analytically, and illustrated numerically

The Cross Product of Two Vectors Is Not Just Another Vector--A Major Misconception Being Perpetuated in Calculus and Vector Analysis Textbooks.

Science.gov (United States)

Elk, Seymour B.

1997-01-01

Suggests that the cross product of two vectors can be more easily and accurately explained by starting from the perspective of dyadics because then the concept of vector multiplication has a simple geometrical picture that encompasses both the dot and cross products in any number of dimensions in terms of orthogonal unit vector components. (AIM)

A terrestrial lidar-based workflow for determining three-dimensional slip vectors and associated uncertainties

Science.gov (United States)

Gold, Peter O.; Cowgill, Eric; Kreylos, Oliver; Gold, Ryan D.

2012-01-01

Three-dimensional (3D) slip vectors recorded by displaced landforms are difficult to constrain across complex fault zones, and the uncertainties associated with such measurements become increasingly challenging to assess as landforms degrade over time. We approach this problem from a remote sensing perspective by using terrestrial laser scanning (TLS) and 3D structural analysis. We have developed an integrated TLS data collection and point-based analysis workflow that incorporates accurate assessments of aleatoric and epistemic uncertainties using experimental surveys, Monte Carlo simulations, and iterative site reconstructions. Our scanning workflow and equipment requirements are optimized for single-operator surveying, and our data analysis process is largely completed using new point-based computing tools in an immersive 3D virtual reality environment. In a case study, we measured slip vector orientations at two sites along the rupture trace of the 1954 Dixie Valley earthquake (central Nevada, United States), yielding measurements that are the first direct constraints on the 3D slip vector for this event. These observations are consistent with a previous approximation of net extension direction for this event. We find that errors introduced by variables in our survey method result in <2.5 cm of variability in components of displacement, and are eclipsed by the 10–60 cm epistemic errors introduced by reconstructing the field sites to their pre-erosion geometries. Although the higher resolution TLS data sets enabled visualization and data interactivity critical for reconstructing the 3D slip vector and for assessing uncertainties, dense topographic constraints alone were not sufficient to significantly narrow the wide (<26°) range of allowable slip vector orientations that resulted from accounting for epistemic uncertainties.

Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector.

Directory of Open Access Journals (Sweden)

Claudia Merkl

Full Text Available Current methods of generating rat induced pluripotent stem cells are based on viral transduction of pluripotency inducing genes (Oct4, Sox2, c-myc and Klf4 into somatic cells. These activate endogenous pluripotency genes and reprogram the identity of the cell to an undifferentiated state. Epigenetic silencing of exogenous genes has to occur to allow normal iPS cell differentiation. To gain more control over the expression of exogenous reprogramming factors, we used a novel doxycycline-inducible plasmid vector encoding Oct4, Sox2, c-Myc and Klf4. To ensure efficient and controlled generation of iPS cells by plasmid transfection we equipped the reprogramming vector with a bacteriophage φC31 attB site and used a φC31 integrase expression vector to enhance vector integration. A series of doxycycline-independent rat iPS cell lines were established. These were characterized by immunocytochemical detection of Oct4, SSEA1 and SSEA4, alkaline phosphatase staining, methylation analysis of the endogenous Oct4 promoter and RT-PCR analysis of endogenous rat pluripotency genes. We also determined the number of vector integrations and the extent to which reprogramming factor gene expression was controlled. Protocols were developed to generate embryoid bodies and rat iPS cells demonstrated as pluripotent by generating derivatives of all three embryonic germ layers in vitro, and teratoma formation in vivo. All data suggest that our rat iPS cells, generated by plasmid based reprogramming, are similar to rat ES cells. Methods of DNA transfection, protein transduction and feeder-free monolayer culture of rat iPS cells were established to enable future applications.

Major vectors and vector-borne diseases in small ruminants in Ethiopia: A systematic review.

Science.gov (United States)

Asmare, Kassahun; Abayneh, Takele; Sibhat, Berhanu; Shiferaw, Dessie; Szonyi, Barbara; Krontveit, Randi I; Skjerve, Eystein; Wieland, Barbara

2017-06-01

Vector-borne diseases are among major health constraints of small ruminant in Ethiopia. While various studies on single vector-borne diseases or presence of vectors have been conducted, no summarized evidence is available on the occurrence of these diseases and the related vectors. This systematic literature review provides a comprehensive summary on major vectors and vector-borne diseases in small ruminants in Ethiopia. Search for published and unpublished literature was conducted between 8th of January and 25th of June 2015. The search was both manual and electronic. The databases used in electronic search were PubMed, Web of Science, CAB Direct and AJOL. For most of the vector-borne diseases, the summary was limited to narrative synthesis due to lack of sufficient data. Meta-analysis was computed for trypanosomosis and dermatophilosis while meta-regression and sensitivity analysis was done only for trypanososmosis due to lack of sufficient reports on dermatophilosis. Owing emphasis to their vector role, ticks and flies were summarized narratively at genera/species level. In line with inclusion criteria, out of 106 initially identified research reports 43 peer-reviewed articles passed the quality assessment. Data on 7 vector-borne diseases were extracted at species and region level from each source. Accordingly, the pooled prevalence estimate of trypanosomosis was 3.7% with 95% confidence interval (CI) 2.8, 4.9), while that of dermatophilosis was 3.1% (95% CI: 1.6, 6.0). The in-between study variance noted for trypanosomosis was statistically significant (pparasitic presence in blood was documented for babesiosis (3.7% in goats); and anaplasmosis (3.9% in sheep). Serological evidence was retrieved for bluetongue ranging from 34.1% to 46.67% in sheep, and coxiellosis was 10.4% in goats. There was also molecular evidence on the presence of theileriosis in sheep (93%, n=160) and goats (1.9%, n=265). Regarding vectors of veterinary importance, 14 species of ticks in

GPU Accelerated Vector Median Filter

Science.gov (United States)

Aras, Rifat; Shen, Yuzhong

2011-01-01

Noise reduction is an important step for most image processing tasks. For three channel color images, a widely used technique is vector median filter in which color values of pixels are treated as 3-component vectors. Vector median filters are computationally expensive; for a window size of n x n, each of the n(sup 2) vectors has to be compared with other n(sup 2) - 1 vectors in distances. General purpose computation on graphics processing units (GPUs) is the paradigm of utilizing high-performance many-core GPU architectures for computation tasks that are normally handled by CPUs. In this work. NVIDIA's Compute Unified Device Architecture (CUDA) paradigm is used to accelerate vector median filtering. which has to the best of our knowledge never been done before. The performance of GPU accelerated vector median filter is compared to that of the CPU and MPI-based versions for different image and window sizes, Initial findings of the study showed 100x improvement of performance of vector median filter implementation on GPUs over CPU implementations and further speed-up is expected after more extensive optimizations of the GPU algorithm .

Effects of Climate and Climate Change on Vectors and Vector-Borne Diseases: Ticks Are Different.

Science.gov (United States)

Ogden, Nick H; Lindsay, L Robbin

2016-08-01

There has been considerable debate as to whether global risk from vector-borne diseases will be impacted by climate change. This has focussed on important mosquito-borne diseases that are transmitted by the vectors from infected to uninfected humans. However, this debate has mostly ignored the biological diversity of vectors and vector-borne diseases. Here, we review how climate and climate change may impact those most divergent of arthropod disease vector groups: multivoltine insects and hard-bodied (ixodid) ticks. We contrast features of the life cycles and behaviour of these arthropods, and how weather, climate, and climate change may have very different impacts on the spatiotemporal occurrence and abundance of vectors, and the pathogens they transmit. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Hierarchal scalar and vector tetrahedra

International Nuclear Information System (INIS)

Webb, J.P.; Forghani, B.

1993-01-01

A new set of scalar and vector tetrahedral finite elements are presented. The elements are hierarchal, allowing mixing of polynomial orders; scalar orders up to 3 and vector orders up to 2 are defined. The vector elements impose tangential continuity on the field but not normal continuity, making them suitable for representing the vector electric or magnetic field. Further, the scalar and vector elements are such that they can easily be used in the same mesh, a requirement of many quasi-static formulations. Results are presented for two 50 Hz problems: the Bath Cube, and TEAM Problem 7

Generation of arbitrary vector fields based on a pair of orthogonal elliptically polarized base vectors.

Science.gov (United States)

Xu, Danfeng; Gu, Bing; Rui, Guanghao; Zhan, Qiwen; Cui, Yiping

2016-02-22

We present an arbitrary vector field with hybrid polarization based on the combination of a pair of orthogonal elliptically polarized base vectors on the Poincaré sphere. It is shown that the created vector field is only dependent on the latitude angle 2χ but is independent on the longitude angle 2ψ on the Poincaré sphere. By adjusting the latitude angle 2χ, which is related to two identical waveplates in a common path interferometric arrangement, one could obtain arbitrary type of vector fields. Experimentally, we demonstrate the generation of such kind of vector fields and confirm the distribution of state of polarization by the measurement of Stokes parameters. Besides, we investigate the tight focusing properties of these vector fields. It is found that the additional degree of freedom 2χ provided by arbitrary vector field with hybrid polarization allows one to control the spatial structure of polarization and to engineer the focusing field.

Calculus with vectors

CERN Document Server

Treiman, Jay S

2014-01-01

Calculus with Vectors grew out of a strong need for a beginning calculus textbook for undergraduates who intend to pursue careers in STEM. fields. The approach introduces vector-valued functions from the start, emphasizing the connections between one-variable and multi-variable calculus. The text includes early vectors and early transcendentals and includes a rigorous but informal approach to vectors. Examples and focused applications are well presented along with an abundance of motivating exercises. All three-dimensional graphs have rotatable versions included as extra source materials and may be freely downloaded and manipulated with Maple Player; a free Maple Player App is available for the iPad on iTunes. The approaches taken to topics such as the derivation of the derivatives of sine and cosine, the approach to limits, and the use of "tables" of integration have been modified from the standards seen in other textbooks in order to maximize the ease with which students may comprehend the material. Additio...

Test of understanding of vectors: A reliable multiple-choice vector concept test

Science.gov (United States)

Barniol, Pablo; Zavala, Genaro

2014-06-01

In this article we discuss the findings of our research on students' understanding of vector concepts in problems without physical context. First, we develop a complete taxonomy of the most frequent errors made by university students when learning vector concepts. This study is based on the results of several test administrations of open-ended problems in which a total of 2067 students participated. Using this taxonomy, we then designed a 20-item multiple-choice test [Test of understanding of vectors (TUV)] and administered it in English to 423 students who were completing the required sequence of introductory physics courses at a large private Mexican university. We evaluated the test's content validity, reliability, and discriminatory power. The results indicate that the TUV is a reliable assessment tool. We also conducted a detailed analysis of the students' understanding of the vector concepts evaluated in the test. The TUV is included in the Supplemental Material as a resource for other researchers studying vector learning, as well as instructors teaching the material.

Semiconductor Manufacturing equipment introduction

International Nuclear Information System (INIS)

Im, Jong Sun

2001-02-01

This book deals with semiconductor manufacturing equipment. It is comprised of nine chapters, which are manufacturing process of semiconductor device, history of semiconductor manufacturing equipment, kinds and role of semiconductor manufacturing equipment, construction and method of semiconductor manufacturing equipment, introduction of various semiconductor manufacturing equipment, spots of semiconductor manufacturing, technical elements of semiconductor manufacturing equipment, road map of technology of semiconductor manufacturing equipment and semiconductor manufacturing equipment in the 21st century.

Leishmaniasis vector behaviour in Kenya

International Nuclear Information System (INIS)

Mutinga, M.J.

1980-01-01

Leishmaniasis in Kenya exists in two forms: cutaneous and visceral. The vectors of visceral leishmaniasis have been the subject of investigation by various researchers since World War II, when the outbreak of the disease was first noticed. The vectors of cutaneous leishmaniasis were first worked on only a decade ago after the discovery of the disease focus in Mt. Elgon. The vector behaviour of these diseases, namely Phlebotomus pedifer, the vector of cutaneous leishmaniasis, and Phlebotomus martini, the vector of visceral leishmaniasis, are discussed in detail. P. pedifer has been found to breed and bite inside caves, whereas P. martini mainly bites inside houses. (author)

Learning with LOGO: Logo and Vectors.

Science.gov (United States)

Lough, Tom; Tipps, Steve

1986-01-01

This is the first of a two-part series on the general concept of vector space. Provides tool procedures to allow investigation of vector properties, vector addition and subtraction, and X and Y components. Lists several sources of additional vector ideas. (JM)

Electrical equipment qualification

International Nuclear Information System (INIS)

Farmer, W.S.

1983-01-01

Electrical equipment qualification research programs being carried out by CEA, JAERI, and Sandia Laboratories are discussed. Objectives of the program are: (1) assessment of accident simulation methods for electrical equipment qualification testing; lower coarse (2) evaluation of equipment aging and accelerated aging methods; (3) determine radiation dose spectrum to electrical equipment and assess simulation methods for qualification; (4) identify inadequacies in electrical equipment qualification procedures and standards and potential failure modes; and (5) provide data for verifying and improving standards, rules and regulatory guides

Strangeness Vector and Axial-Vector Form Factors of the Nucleon

Directory of Open Access Journals (Sweden)

Pate Stephen

2014-03-01

Full Text Available A revised global fit of electroweak ep and vp elastic scattering data has been performed, with the goal of determining the strange quark contribution to the vector and axial-vector form factors of the nucleon in the momentum-transfer range 0 < Q2 < 1 GeV2. The two vector (electric and magnetic form factors GsE(Q2 and GsM(Q2 are strongly constrained by ep elastic scattering data, while the major source of information on the axial-vector form factor GsA(Q2 is vp scattering data. Combining the two kinds of data into a single global fit makes possible additional precision in the determination of these form factors, and provides a unique way to determine the strange quark contribution to the nucleon spin, ΔS , independently of leptonic deep-inelastic scattering. The fit makes use of data from the BNL-E734, SAMPLE, HAPPEx, G0, and PVA4 experiments; we will also compare the result of the fit with recent data from MiniBooNE, and anticipate how this fit can be improved when new data from MicroBooNE become available.

Multi-task Vector Field Learning.

Science.gov (United States)

Lin, Binbin; Yang, Sen; Zhang, Chiyuan; Ye, Jieping; He, Xiaofei

2012-01-01

Multi-task learning (MTL) aims to improve generalization performance by learning multiple related tasks simultaneously and identifying the shared information among tasks. Most of existing MTL methods focus on learning linear models under the supervised setting. We propose a novel semi-supervised and nonlinear approach for MTL using vector fields. A vector field is a smooth mapping from the manifold to the tangent spaces which can be viewed as a directional derivative of functions on the manifold. We argue that vector fields provide a natural way to exploit the geometric structure of data as well as the shared differential structure of tasks, both of which are crucial for semi-supervised multi-task learning. In this paper, we develop multi-task vector field learning (MTVFL) which learns the predictor functions and the vector fields simultaneously. MTVFL has the following key properties. (1) The vector fields MTVFL learns are close to the gradient fields of the predictor functions. (2) Within each task, the vector field is required to be as parallel as possible which is expected to span a low dimensional subspace. (3) The vector fields from all tasks share a low dimensional subspace. We formalize our idea in a regularization framework and also provide a convex relaxation method to solve the original non-convex problem. The experimental results on synthetic and real data demonstrate the effectiveness of our proposed approach.

Space Heating Equipment

Energy Technology Data Exchange (ETDEWEB)

Rafferty, Kevin D.

1998-01-01

The performance evaluation of space heating equipment for a geothermal application is generally considered from either of two perspectives: (a) selecting equipment for installation in new construction, or (b) evaluating the performance and retrofit requirements of an existing system. With regard to new construction, the procedure is relatively straightforward. Once the heating requirements are determined, the process need only involve the selection of appropriately sized hot water heating equipment based on the available water temperature. It is important to remember that space heating equipment for geothermal applications is the same equipment used in non-geothermal applications. What makes geothermal applications unique is that the equipment is generally applied at temperatures and flow rates that depart significantly from traditional heating system design. This chapter presents general considerations for the performance of heating equipment at non-standard temperature and flow conditions, retrofit of existing systems, and aspects of domestic hot water heating.

A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN vectors and multi-colour analyses

Directory of Open Access Journals (Sweden)

Prokofjeva Maria M

2013-01-01

Full Text Available Abstract Background Despite progress in the development of combined antiretroviral therapies (cART, HIV infection remains a significant challenge for human health. Current problems of cART include multi-drug-resistant virus variants, long-term toxicity and enormous treatment costs. Therefore, the identification of novel effective drugs is urgently needed. Methods We developed a straightforward screening approach for simultaneously evaluating the sensitivity of multiple HIV gag-pol mutants to antiviral drugs in one assay. Our technique is based on multi-colour lentiviral self-inactivating (SIN LeGO vector technology. Results We demonstrated the successful use of this approach for screening compounds against up to four HIV gag-pol variants (wild-type and three mutants simultaneously. Importantly, the technique was adapted to Biosafety Level 1 conditions by utilising ecotropic pseudotypes. This allowed upscaling to a large-scale screening protocol exploited by pharmaceutical companies in a successful proof-of-concept experiment. Conclusions The technology developed here facilitates fast screening for anti-HIV activity of individual agents from large compound libraries. Although drugs targeting gag-pol variants were used here, our approach permits screening compounds that target several different, key cellular and viral functions of the HIV life-cycle. The modular principle of the method also allows the easy exchange of various mutations in HIV sequences. In conclusion, the methodology presented here provides a valuable new approach for the identification of novel anti-HIV drugs.

Enhancing poxvirus vectors vaccine immunogenicity.

Science.gov (United States)

García-Arriaza, Juan; Esteban, Mariano

2014-01-01

Attenuated recombinant poxvirus vectors expressing heterologous antigens from pathogens are currently at various stages in clinical trials with the aim to establish their efficacy. This is because these vectors have shown excellent safety profiles, significant immunogenicity against foreign expressed antigens and are able to induce protective immune responses. In view of the limited efficacy triggered by some poxvirus strains used in clinical trials (i.e, ALVAC in the RV144 phase III clinical trial for HIV), and of the restrictive replication capacity of the highly attenuated vectors like MVA and NYVAC, there is a consensus that further improvements of these vectors should be pursuit. In this review we considered several strategies that are currently being implemented, as well as new approaches, to improve the immunogenicity of the poxvirus vectors. This includes heterologous prime/boost protocols, use of co-stimulatory molecules, deletion of viral immunomodulatory genes still present in the poxvirus genome, enhancing virus promoter strength, enhancing vector replication capacity, optimizing expression of foreign heterologous sequences, and the combined use of adjuvants. An optimized poxvirus vector triggering long-lasting immunity with a high protective efficacy against a selective disease should be sought.

Stable piecewise polynomial vector fields

Directory of Open Access Journals (Sweden)

Claudio Pessoa

2012-09-01

Full Text Available Let $N={y>0}$ and $S={y<0}$ be the semi-planes of $mathbb{R}^2$ having as common boundary the line $D={y=0}$. Let $X$ and $Y$ be polynomial vector fields defined in $N$ and $S$, respectively, leading to a discontinuous piecewise polynomial vector field $Z=(X,Y$. This work pursues the stability and the transition analysis of solutions of $Z$ between $N$ and $S$, started by Filippov (1988 and Kozlova (1984 and reformulated by Sotomayor-Teixeira (1995 in terms of the regularization method. This method consists in analyzing a one parameter family of continuous vector fields $Z_{epsilon}$, defined by averaging $X$ and $Y$. This family approaches $Z$ when the parameter goes to zero. The results of Sotomayor-Teixeira and Sotomayor-Machado (2002 providing conditions on $(X,Y$ for the regularized vector fields to be structurally stable on planar compact connected regions are extended to discontinuous piecewise polynomial vector fields on $mathbb{R}^2$. Pertinent genericity results for vector fields satisfying the above stability conditions are also extended to the present case. A procedure for the study of discontinuous piecewise vector fields at infinity through a compactification is proposed here.

Transversals of Complex Polynomial Vector Fields

DEFF Research Database (Denmark)

Dias, Kealey

Vector fields in the complex plane are defined by assigning the vector determined by the value P(z) to each point z in the complex plane, where P is a polynomial of one complex variable. We consider special families of so-called rotated vector fields that are determined by a polynomial multiplied...... by rotational constants. Transversals are a certain class of curves for such a family of vector fields that represent the bifurcation states for this family of vector fields. More specifically, transversals are curves that coincide with a homoclinic separatrix for some rotation of the vector field. Given...... a concrete polynomial, it seems to take quite a bit of work to prove that it is generic, i.e. structurally stable. This has been done for a special class of degree d polynomial vector fields having simple equilibrium points at the d roots of unity, d odd. In proving that such vector fields are generic...

Vector optimization set-valued and variational analysis

CERN Document Server

Chen, Guang-ya; Yang, Xiaogi

2005-01-01

This book is devoted to vector or multiple criteria approaches in optimization. Topics covered include: vector optimization, vector variational inequalities, vector variational principles, vector minmax inequalities and vector equilibrium problems. In particular, problems with variable ordering relations and set-valued mappings are treated. The nonlinear scalarization method is extensively used throughout the book to deal with various vector-related problems. The results presented are original and should be interesting to researchers and graduates in applied mathematics and operations research

Implicit Real Vector Automata

Directory of Open Access Journals (Sweden)

Jean-François Degbomont

2010-10-01

Full Text Available This paper addresses the symbolic representation of non-convex real polyhedra, i.e., sets of real vectors satisfying arbitrary Boolean combinations of linear constraints. We develop an original data structure for representing such sets, based on an implicit and concise encoding of a known structure, the Real Vector Automaton. The resulting formalism provides a canonical representation of polyhedra, is closed under Boolean operators, and admits an efficient decision procedure for testing the membership of a vector.

Vectoring of parallel synthetic jets

Science.gov (United States)

Berk, Tim; Ganapathisubramani, Bharathram; Gomit, Guillaume

2015-11-01

A pair of parallel synthetic jets can be vectored by applying a phase difference between the two driving signals. The resulting jet can be merged or bifurcated and either vectored towards the actuator leading in phase or the actuator lagging in phase. In the present study, the influence of phase difference and Strouhal number on the vectoring behaviour is examined experimentally. Phase-locked vorticity fields, measured using Particle Image Velocimetry (PIV), are used to track vortex pairs. The physical mechanisms that explain the diversity in vectoring behaviour are observed based on the vortex trajectories. For a fixed phase difference, the vectoring behaviour is shown to be primarily influenced by pinch-off time of vortex rings generated by the synthetic jets. Beyond a certain formation number, the pinch-off timescale becomes invariant. In this region, the vectoring behaviour is determined by the distance between subsequent vortex rings. We acknowledge the financial support from the European Research Council (ERC grant agreement no. 277472).

Vectorization in quantum chemistry

International Nuclear Information System (INIS)

Saunders, V.R.

1987-01-01

It is argued that the optimal vectorization algorithm for many steps (and sub-steps) in a typical ab initio calculation of molecular electronic structure is quite strongly dependent on the target vector machine. Details such as the availability (or lack) of a given vector construct in the hardware, vector startup times and asymptotic rates must all be considered when selecting the optimal algorithm. Illustrations are drawn from: gaussian integral evaluation, fock matrix construction, 4-index transformation of molecular integrals, direct-CI methods, the matrix multiply operation. A cross comparison of practical implementations on the CDC Cyber 205, the Cray-IS and Cray-XMP machines is presented. To achieve portability while remaining optimal on a wide range of machines it is necessary to code all available algorithms in a machine independent manner, and to select the appropriate algorithm using a procedure which is based on machine dependent parameters. Most such parameters concern the timing of certain vector loop kernals, which can usually be derived from a 'bench-marking' routine executed prior to the calculation proper

Health education: a strategy of care for the lay caregiver Educación en salud: una estrategia de cuidado al cuidador lego Educação em saúde: uma estratégia de cuidado ao cuidador leigo

Directory of Open Access Journals (Sweden)

Luccas Melo de Souza

2007-04-01

Full Text Available This article aimed to reflect about the importance of the role nurses perform in strategies of health education to lay caregivers, who are important actors in the health/disease process. It is a thematic reflection, built through bibliographic review, which discusses the role of lay caregivers in different stages of the life cycle. Considering the participation of lay caregivers in the Brazilian reality, strategies have been sought to include them in the health care, given the little attention Public Policies have given to them. Therefore, the nurses as health educators, must offer support to the lay caregivers helping them to choose among available alternatives, while delivering care, to not harm their own health. Concluding, health education can be an alternative to offer attention to the lay caregivers, while the nurse has important role in the development of alternatives.Este artículo tiene por objetivo reflexionar acerca de la importancia de la intervención de enfermería a través de estrategias de educación en salud, para los cuidadores legos, actores fundamentales en el proceso salud/enfermedad. Se trata de una reflexión temática, construida por medio de la búsqueda bibliográfica, a través de la cual se discute el rol de los cuidadores en las diferentes etapas del ciclo vital. Tomando como base la actual participación de los cuidadores legos en el escenario brasileño, se buscan estrategias para incluirlos en la asistencia de salud teniendo en vista la poca relevancia que las Políticas Públicas les han demostrado. Así, el enfermero, como educador en salud, debe ofrecer subsidios a los cuidadores legos para que sean capaces de escoger entre las alternativas disponibles para el cuidado de los enfermos, de forma tal que esta función no perjudique la salud del paciente. Se concluye que la educación en salud puede ser una forma alternativa para ofrecer atención de salud a los cuidadores legos, siendo el rol del enfermero

Properties of vector and axial-vector mesons from a generalized Nambu-Jona-Lasinio model

International Nuclear Information System (INIS)

Bernard, V.; Meissner, U.G.; Massachusetts Inst. of Tech., Cambridge; Massachusetts Inst. of Tech., Cambridge

1988-01-01

We construct a generalized Nambu-Jona-Lasinio lagrangian including scalar, pseudoscalar, vector and axial-vector mesons. We specialize to the two-flavor case. The properties of the structured vacuum as well as meson masses and coupling constants are calculated giving an overall agreement within 20% of the experimental data. We investigate the meson properties at finite density. In contrast to the mass of the scalar σ-meson, which decreases sharply with increasing density, the vector meson masses are almost independent of density. Furthermore, the vector-meson-quark coupling constants are also stable against density changes. We point out that these results imply a softening of the nuclear equation of state at high densities. Furthermore, we discuss the breakdown of the KFSR relation on the quark level as well as other deviations from phenomenological concepts such as universality and vector meson dominance. (orig.)

Vector geometry

CERN Document Server

Robinson, Gilbert de B

2011-01-01

This brief undergraduate-level text by a prominent Cambridge-educated mathematician explores the relationship between algebra and geometry. An elementary course in plane geometry is the sole requirement for Gilbert de B. Robinson's text, which is the result of several years of teaching and learning the most effective methods from discussions with students. Topics include lines and planes, determinants and linear equations, matrices, groups and linear transformations, and vectors and vector spaces. Additional subjects range from conics and quadrics to homogeneous coordinates and projective geom

Electroproduction and photoproduction of vector mesons and generalized vector meson dominance

International Nuclear Information System (INIS)

Fraas, H.; Kuroda, M.

1977-05-01

Using generalized vector meson dominance, electro- and photoproduction of vector mesons is studied. The unnatural parity exchange part of ω(1.2) production is estimated to be about one fourth of that of ω-production. The off diagonal transition model suggests the suppression of diffractive rho(1.2) and ω(1.2) production. (orig.) [de

Vector (two-dimensional) magnetic phenomena

International Nuclear Information System (INIS)

Enokizono, Masato

2002-01-01

In this paper, some interesting phenomena were described from the viewpoint of two-dimensional magnetic property, which is reworded with the vector magnetic property. It shows imperfection of conventional magnetic property and some interested phenomena were discovered, too. We found magnetic materials had the strong nonlinearity both magnitude and spatial phase due to the relationship between the magnetic field strength H-vector and the magnetic flux density B-vector. Therefore, magnetic properties should be defined as the vector relationship. Furthermore, the new Barukhausen signal was observed under rotating flux. (Author)

Quark-gluon plasma tomography by vector mesons

International Nuclear Information System (INIS)

Lovas, I.; Schram, Zs.; Csernai, L.P.; Hungarian Academy of Sciences, Budapest; Nyiri, A.

2001-01-01

The fireball formed in a heavy ion collision is characterized by the impact parameter vector b-vector, which can be determined from the multiplicity and the angular distribution of the reaction products. By appropriate rotations the b-vector vectors of each collision can be aligned into a fixed direction. Using the measured values of the momentum distributions independent integral equations can be formulated for the unknown emission densities (E M (r-vector)) and for the unknown absorption densities (Δμ(r-vector)) of the different vector mesons. (author)

Vector superconductivity in cosmic strings

International Nuclear Information System (INIS)

Dvali, G.R.; Mahajan, S.M.

1992-03-01

We argue that in most realistic cases, the usual Witten-type bosonic superconductivity of the cosmic string is automatically (independent of the existence of superconducting currents) accompanied by the condensation of charged gauge vector bosons in the core giving rise to a new vector type superconductivity. The value of the charged vector condensate is related with the charged scalar expectation value, and vanishes only if the latter goes to zero. The mechanism for the proposed vector superconductivity, differing fundamentally from those in the literature, is delineated using the simplest realistic example of the two Higgs doublet standard model interacting with the extra cosmic string. It is shown that for a wide range of parameters, for which the string becomes scalarly superconducting, W boson condensates (the sources of vector superconductivity) are necessarily excited. (author). 14 refs

Brane vector phenomenology

International Nuclear Information System (INIS)

Clark, T.E.; Love, S.T.; Nitta, Muneto; Veldhuis, T. ter; Xiong, C.

2009-01-01

Local oscillations of the brane world are manifested as massive vector fields. Their coupling to the Standard Model can be obtained using the method of nonlinear realizations of the spontaneously broken higher-dimensional space-time symmetries, and to an extent, are model independent. Phenomenological limits on these vector field parameters are obtained using LEP collider data and dark matter constraints

Distribution of Brugia malayi larvae and DNA in vector and non-vector mosquitoes: implications for molecular diagnostics

Directory of Open Access Journals (Sweden)

Christensen Bruce M

2009-11-01

Full Text Available Abstract Background The purpose of this study was to extend prior studies of molecular detection of Brugia malayi DNA in vector (Aedes aegypti- Liverpool and non-vector (Culex pipiens mosquitoes at different times after ingestion of infected blood. Results Parasite DNA was detected over a two week time course in 96% of pooled thoraces of vector mosquitoes. In contrast, parasite DNA was detected in only 24% of thorax pools from non-vectors; parasite DNA was detected in 56% of midgut pools and 47% of abdomen pools from non-vectors. Parasite DNA was detected in vectors in the head immediately after the blood meal and after 14 days. Parasite DNA was also detected in feces and excreta of the vector and non-vector mosquitoes which could potentially confound results obtained with field samples. However, co-housing experiments failed to demonstrate transfer of parasite DNA from infected to non-infected mosquitoes. Parasites were also visualized in mosquito tissues by immunohistololgy using an antibody to the recombinant filarial antigen Bm14. Parasite larvae were detected consistently after mf ingestion in Ae. aegypti- Liverpool. Infectious L3s were seen in the head, thorax and abdomen of vector mosquitoes 14 days after Mf ingestion. In contrast, parasites were only detected by histology shortly after the blood meal in Cx. pipiens, and these were not labeled by the antibody. Conclusion This study provides new information on the distribution of filarial parasites and parasite DNA in vector and non-vector mosquitoes. This information should be useful for those involved in designing and interpreting molecular xenomonitoring studies.

Insecticide resistance in disease vectors from Mayotte: an opportunity for integrated vector management.

Science.gov (United States)

Pocquet, Nicolas; Darriet, Frédéric; Zumbo, Betty; Milesi, Pascal; Thiria, Julien; Bernard, Vincent; Toty, Céline; Labbé, Pierrick; Chandre, Fabrice

2014-07-01

Mayotte, a small island in the Indian Ocean, has been affected for many years by vector-borne diseases. Malaria, Bancroftian filariasis, dengue, chikungunya and Rift Valley fever have circulated or still circulate on the island. They are all transmitted by Culicidae mosquitoes. To limit the impact of these diseases on human health, vector control has been implemented for more than 60 years on Mayotte. In this study, we assessed the resistance levels of four major vector species (Anopheles gambiae, Culex pipiens quinquefasciatus, Aedes aegypti and Aedes albopictus) to two types of insecticides: i) the locally currently-used insecticides (organophosphates, pyrethroids) and ii) alternative molecules that are promising for vector control and come from different insecticide families (bacterial toxins or insect growth regulators). When some resistance was found to one of these insecticides, we characterized the mechanisms involved. Larval and adult bioassays were used to evaluate the level of resistance. When resistance was found, we tested for the presence of metabolic resistance through detoxifying enzyme activity assays, or for target-site mutations through molecular identification of known resistance alleles. Resistance to currently-used insecticides varied greatly between the four vector species. While no resistance to any insecticides was found in the two Aedes species, bioassays confirmed multiple resistance in Cx. p. quinquefasciatus (temephos: ~ 20 fold and deltamethrin: only 10% mortality after 24 hours). In An. gambiae, resistance was scarce: only a moderate resistance to temephos was found (~5 fold). This resistance appears to be due only to carboxyl-esterase overexpression and not to target modification. Finally, and comfortingly, none of the four species showed resistance to any of the new insecticides. The low resistance observed in Mayotte's main disease vectors is particularly interesting, because it leaves a range of tools useable by vector control

A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance

Directory of Open Access Journals (Sweden)

Elizabeth M Everson

2016-01-01

Full Text Available Hematopoietic stem cell (HSC gene therapy using retroviral vectors has immense potential, but vector-mediated genotoxicity limits use in the clinic. Lentiviral vectors are less genotoxic than gammaretroviral vectors and have become the vector of choice in clinical trials. Foamy retroviral vectors have a promising integration profile and are less prone to read-through transcription than gammaretroviral or lentiviral vectors. Here, we directly compared the safety and efficacy of foamy vectors to lentiviral vectors in human CD34+ repopulating cells in immunodeficient mice. To increase their genotoxic potential, foamy and lentiviral vectors with identical transgene cassettes with a known genotoxic spleen focus forming virus promoter were used. Both vectors resulted in efficient marking in vivo and a total of 825 foamy and 460 lentiviral vector unique integration sites were recovered in repopulating cells 19 weeks after transplantation. Foamy vector proviruses were observed less often near RefSeq gene and proto-oncogene transcription start sites than lentiviral vectors. The foamy vector group were also more polyclonal with fewer dominant clones (two out of six mice than the lentiviral vector group (eight out of eight mice, and only lentiviral vectors had integrants near known proto-oncogenes in dominant clones. Our data further support the relative safety of foamy vectors for HSC gene therapy.

Tensor Calculus: Unlearning Vector Calculus

Science.gov (United States)

Lee, Wha-Suck; Engelbrecht, Johann; Moller, Rita

2018-01-01

Tensor calculus is critical in the study of the vector calculus of the surface of a body. Indeed, tensor calculus is a natural step-up for vector calculus. This paper presents some pitfalls of a traditional course in vector calculus in transitioning to tensor calculus. We show how a deeper emphasis on traditional topics such as the Jacobian can…

Vector mesons on the light front

International Nuclear Information System (INIS)

Naito, K.; Maedan, S.; Itakura, K.

2004-01-01

We apply the light-front quantization to the Nambu-Jona-Lasinio model with the vector interaction, and compute vector meson's mass and light-cone wavefunction in the large N limit. Following the same procedure as in the previous analyses for scalar and pseudo-scalar mesons, we derive the bound-state equations of a qq-bar system in the vector channel. We include the lowest order effects of the vector interaction. The resulting transverse and longitudinal components of the bound-state equation look different from each other. But eventually after imposing an appropriate cutoff, one finds these two are identical, giving the same mass and the same (spin-independent) light-cone wavefunction. Mass of the vector meson decreases as one increases the strength of the vector interaction

Does the delta quench Gamow-Teller strength in (p,n)- and (p vector,p vector')-reactions

International Nuclear Information System (INIS)

Osterfeld, F.; Schulte, A.; Udagawa, T.; Yabe, M.

1986-01-01

Microscopic analyses of complete forward angle intermediate energy (p,n)-, ( 3 He,t)- and (p vector,p vector')-spin-flip spectra are presented for the reactions 90 Zr(p,n), 90 Zr( 3 He,t) and 90 Zr(p vector,p vector'). It is shown that the whole spectra up to high excitation energies (E X ∝50 MeV) are the result of correlated one-particle-one-hole (1p1h) spin-isospin transitions only. The spectra reflect, therefore, the linear spin-isospin response of the target nucleus to the probing external hadronic fields. Our results suggest that the measured (p,n)-, ( 3 He,t)- and (p vector,p vector')-cross sections are compatible with the transition strength predictions as obtained from random phase approximation (RPA) calculations. This means that the Δ isobar quenching mechanism is likely to be rather small. (orig.)

On the Vectorization of FIR Filterbanks

Directory of Open Access Journals (Sweden)

Barbedo Jayme Garcia Arnal

2007-01-01

Full Text Available This paper presents a vectorization technique to implement FIR filterbanks. The word vectorization, in the context of this work, refers to a strategy in which all iterative operations are replaced by equivalent vector and matrix operations. This approach allows that the increasing parallelism of the most recent computer processors and systems be properly explored. The vectorization techniques are applied to two kinds of FIR filterbanks (conventional and recursi ve, and are presented in such a way that they can be easily extended to any kind of FIR filterbanks. The vectorization approach is compared to other kinds of implementation that do not explore the parallelism, and also to a previous FIR filter vectorization approach. The tests were performed in Matlab and , in order to explore different aspects of the proposed technique.

On the Vectorization of FIR Filterbanks

Directory of Open Access Journals (Sweden)

Amauri Lopes

2007-01-01

Full Text Available This paper presents a vectorization technique to implement FIR filterbanks. The word vectorization, in the context of this work, refers to a strategy in which all iterative operations are replaced by equivalent vector and matrix operations. This approach allows that the increasing parallelism of the most recent computer processors and systems be properly explored. The vectorization techniques are applied to two kinds of FIR filterbanks (conventional and recursi ve, and are presented in such a way that they can be easily extended to any kind of FIR filterbanks. The vectorization approach is compared to other kinds of implementation that do not explore the parallelism, and also to a previous FIR filter vectorization approach. The tests were performed in Matlab and C, in order to explore different aspects of the proposed technique.

RETRIEVAL EQUIPMENT DESCRIPTIONS

International Nuclear Information System (INIS)

J. Steinhoff

1997-01-01

The objective and the scope of this document are to list and briefly describe the major mobile equipment necessary for waste package (WP) retrieval from the proposed subsurface nuclear waste repository at Yucca Mountain. Primary performance characteristics and some specialized design features of the equipment are explained and summarized in the individual subsections of this document. There are no quality assurance requirements or QA controls in this document. Retrieval under normal conditions is accomplished with the same fleet of equipment as is used for emplacement. Descriptions of equipment used for retrieval under normal conditions is found in Emplacement Equipment Descriptions, DI: BCAF00000-01717-5705-00002 (a document in progress). Equipment used for retrieval under abnormal conditions is addressed in this document and consists of the following: (1) Inclined Plane Hauler; (2) Bottom Lift Transporter; (3) Load Haul Dump (LHD) Loader; (4) Heavy Duty Forklift for Emplacement Drifts; (5) Covered Shuttle Car; (6) Multipurpose Vehicle; and (7) Scaler

Two-hadron saturation for the pseudoscalar-vector-vector correlator and phenomenological applications

Energy Technology Data Exchange (ETDEWEB)

Husek, Tomas [Charles University, Faculty of Mathematics and Physics, Institute of Particle and Nuclear Physics, Prague 8 (Czech Republic); Leupold, Stefan [Uppsala Universitet, Institutionen foer Fysik och Astronomi, Box 516, Uppsala (Sweden)

2015-12-15

The pseudoscalar-vector-vector correlator is constructed using two meson multiplets in the vector and two in the pseudoscalar channel. The parameters are constrained by the operator product expansion at leading order where two or all three momenta are considered as large. Demanding in addition the Brodsky-Lepage limit one obtains (in the chiral limit) pion-vector-vector (πVV) correlator with only one free parameter. The singly virtual pion transition form factor F{sub π{sup 0}γγ*} and the decay width of ω → π{sup 0}γ are independent of this parameter and can serve as cross-checks of the results. The free parameter is determined from a fit of the ω-π transition form factor F{sub π{sup 0}ωγ*}. The resulting πVV correlator is used to calculate the decay widths ω → π{sup 0}e{sup +}e{sup -} and ω → π{sup 0}μ{sup +}μ{sup -} and finally the widths of the rare decay π{sup 0} → e{sup +}e{sup -} and of the Dalitz decay π{sup 0} → e{sup +}e{sup -}γ. Incorporating radiative QED corrections the calculations of π{sup 0} decays are compared to the KTeV results. We find a deviation of 2 σ or less for the rare pion decay. (orig.)

Modular Ligation Extension of Guide RNA Operons (LEGO) for Multiplexed dCas9 Regulation of Metabolic Pathways in Saccharomyces cerevisiae.

Science.gov (United States)

Deaner, Matthew; Holzman, Allison; Alper, Hal S

2018-04-16

Metabolic engineering typically utilizes a suboptimal step-wise gene target optimization approach to parse a highly connected and regulated cellular metabolism. While the endonuclease-null CRISPR/Cas system has enabled gene expression perturbations without genetic modification, it has been mostly limited to small sets of gene targets in eukaryotes due to inefficient methods to assemble and express large sgRNA operons. In this work, we develop a TEF1p-tRNA expression system and demonstrate that the use of tRNAs as splicing elements flanking sgRNAs provides higher efficiency than both Pol III and ribozyme-based expression across a variety of single sgRNA and multiplexed contexts. Next, we devise and validate a scheme to allow modular construction of tRNA-sgRNA (TST) operons using an iterative Type IIs digestion/ligation extension approach, termed CRISPR-Ligation Extension of sgRNA Operons (LEGO). This approach enables facile construction of large TST operons. We demonstrate this utility by constructing a metabolic rewiring prototype for 2,3-butanediol production in 2 distinct yeast strain backgrounds. These results demonstrate that our approach can act as a surrogate for traditional genetic modification on a much shorter design-cycle timescale. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Vector borne diseases

OpenAIRE

Melillo Fenech, Tanya

2010-01-01

A vector-borne disease is one in which the pathogenic microorganism is transmitted from an infected individual to another individual by an arthropod or other agent. The transmission depends upon the attributes and requirements of at least three different Iiving organisms : the pathologic agent which is either a virus, protozoa, bacteria or helminth (worm); the vector, which is commonly an arthropod such as ticks or mosquitoes; and the human host.

Scanning vector Hall probe microscopy

International Nuclear Information System (INIS)

Cambel, V.; Gregusova, D.; Fedor, J.; Kudela, R.; Bending, S.J.

2004-01-01

We have developed a scanning vector Hall probe microscope for mapping magnetic field vector over magnetic samples. The microscope is based on a micromachined Hall sensor and the cryostat with scanning system. The vector Hall sensor active area is ∼5x5 μm 2 . It is realized by patterning three Hall probes on the tilted faces of GaAs pyramids. Data from these 'tilted' Hall probes are used to reconstruct the full magnetic field vector. The scanning area of the microscope is 5x5 mm 2 , space resolution 2.5 μm, field resolution ∼1 μT Hz -1/2 at temperatures 10-300 K

Data communication equipment

International Nuclear Information System (INIS)

Kim, Hak Seon; Lee, Sang Mok

1998-02-01

The contents of this book are introduction of data communication on definition, purpose and history, information terminal about data communication system and data transmission system, data transmit equipment of summary, transmission cable, data port, concentrator and front-end processor, audio communication equipment like phones, radio communication equipment of summary on foundation of electromagnetic waves, AM transmitter, AM receiver, FM receiver and FM transmitter, a satellite and mobile communication equipment such as earth station, TT and C and Cellular phone, video telephone and new media apparatus.

Medical equipment management

CERN Document Server

Willson, Keith; Tabakov, Slavik

2013-01-01

Know What to Expect When Managing Medical Equipment and Healthcare Technology in Your Organization As medical technology in clinical care becomes more complex, clinical professionals and support staff must know how to keep patients safe and equipment working in the clinical environment. Accessible to all healthcare professionals and managers, Medical Equipment Management presents an integrated approach to managing medical equipment in healthcare organizations. The book explains the underlying principles and requirements and raises awareness of what needs to be done and what questions to ask. I

Non-coaxial superposition of vector vortex beams.

Science.gov (United States)

Aadhi, A; Vaity, Pravin; Chithrabhanu, P; Reddy, Salla Gangi; Prabakar, Shashi; Singh, R P

2016-02-10

Vector vortex beams are classified into four types depending upon spatial variation in their polarization vector. We have generated all four of these types of vector vortex beams by using a modified polarization Sagnac interferometer with a vortex lens. Further, we have studied the non-coaxial superposition of two vector vortex beams. It is observed that the superposition of two vector vortex beams with same polarization singularity leads to a beam with another kind of polarization singularity in their interaction region. The results may be of importance in ultrahigh security of the polarization-encrypted data that utilizes vector vortex beams and multiple optical trapping with non-coaxial superposition of vector vortex beams. We verified our experimental results with theory.

Fractal vector optical fields.

Science.gov (United States)

Pan, Yue; Gao, Xu-Zhen; Cai, Meng-Qiang; Zhang, Guan-Lin; Li, Yongnan; Tu, Chenghou; Wang, Hui-Tian

2016-07-15

We introduce the concept of a fractal, which provides an alternative approach for flexibly engineering the optical fields and their focal fields. We propose, design, and create a new family of optical fields-fractal vector optical fields, which build a bridge between the fractal and vector optical fields. The fractal vector optical fields have polarization states exhibiting fractal geometry, and may also involve the phase and/or amplitude simultaneously. The results reveal that the focal fields exhibit self-similarity, and the hierarchy of the fractal has the "weeding" role. The fractal can be used to engineer the focal field.

Clifford Fourier transform on vector fields.

Science.gov (United States)

Ebling, Julia; Scheuermann, Gerik

2005-01-01

Image processing and computer vision have robust methods for feature extraction and the computation of derivatives of scalar fields. Furthermore, interpolation and the effects of applying a filter can be analyzed in detail and can be advantages when applying these methods to vector fields to obtain a solid theoretical basis for feature extraction. We recently introduced the Clifford convolution, which is an extension of the classical convolution on scalar fields and provides a unified notation for the convolution of scalar and vector fields. It has attractive geometric properties that allow pattern matching on vector fields. In image processing, the convolution and the Fourier transform operators are closely related by the convolution theorem and, in this paper, we extend the Fourier transform to include general elements of Clifford Algebra, called multivectors, including scalars and vectors. The resulting convolution and derivative theorems are extensions of those for convolution and the Fourier transform on scalar fields. The Clifford Fourier transform allows a frequency analysis of vector fields and the behavior of vector-valued filters. In frequency space, vectors are transformed into general multivectors of the Clifford Algebra. Many basic vector-valued patterns, such as source, sink, saddle points, and potential vortices, can be described by a few multivectors in frequency space.

Vector-like quarks: t’ and partners

International Nuclear Information System (INIS)

PANIZZI, L.

2014-01-01

Vector-like quarks are predicted in various scenarios of new physics, and their peculiar signatures from both pair and single production have been already investigated in detail. However no signals of vector-like quarks have been detected so far, pushing limits on their masses above 600–700GeV, depending on assumptions on their couplings. Experimental searches consider specific final states to pose bounds on the mass of a vector-like quark, usually assuming it is the only particle that contributes to the signal of new physics in that specific final state. However, realistic scenarios predict the existence of multiple vector-like quarks, possibly with similar masses. The reinterpretation of mass bounds from experimental searches is therefore not always straightforward. In this analysis I briefly summarise the constraints on vector-like quarks and their possible signatures at the LHC, focusing in particular on a model-independent description of single production processes for vector-like quark that mix with all generations and on the development of a framework to study scenarios with multiple vector-like quarks.

Correlated Topic Vector for Scene Classification.

Science.gov (United States)

Wei, Pengxu; Qin, Fei; Wan, Fang; Zhu, Yi; Jiao, Jianbin; Ye, Qixiang

2017-07-01

Scene images usually involve semantic correlations, particularly when considering large-scale image data sets. This paper proposes a novel generative image representation, correlated topic vector, to model such semantic correlations. Oriented from the correlated topic model, correlated topic vector intends to naturally utilize the correlations among topics, which are seldom considered in the conventional feature encoding, e.g., Fisher vector, but do exist in scene images. It is expected that the involvement of correlations can increase the discriminative capability of the learned generative model and consequently improve the recognition accuracy. Incorporated with the Fisher kernel method, correlated topic vector inherits the advantages of Fisher vector. The contributions to the topics of visual words have been further employed by incorporating the Fisher kernel framework to indicate the differences among scenes. Combined with the deep convolutional neural network (CNN) features and Gibbs sampling solution, correlated topic vector shows great potential when processing large-scale and complex scene image data sets. Experiments on two scene image data sets demonstrate that correlated topic vector improves significantly the deep CNN features, and outperforms existing Fisher kernel-based features.

Charmless Hadronic B Decays into Vector, Axial Vector and Tensor Final States at BaBar

International Nuclear Information System (INIS)

Gandini, Paolo

2012-01-01

We present experimental measurements of branching fraction and longitudinal polarization fraction in charmless hadronic B decays into vector, axial vector and tensor final states with the final dataset of BABAR. Measurements of such kind of decays are a powerful tool both to test the Standard Model and search possible sources of new physics. In this document we present a short review of the last experimental results at BABAR concerning charmless quasi two-body decays in final states containing particles with spin 1 or spin 2 and different parities. This kind of decays has received considerable theoretical interest in the last few years and this particular attention has led to interesting experimental results at the current b-factories. In fact, the study of longitudinal polarization fraction f L in charmless B decays to vector vector (VV), vector axial-vector (VA) and axial-vector axial-vector (AA) mesons provides information on the underlying helicity structure of the decay mechanism. Naive helicity conservation arguments predict a dominant longitudinal polarization fraction f L ∼ 1 for both tree and penguin dominated decays and this pattern seems to be confirmed by tree-dominated B → ρρ and B + → (Omega)ρ + decays. Other penguin dominated decays, instead, show a different behavior: the measured value of f L ∼ 0.5 in B → φK* decays is in contrast with naive Standard Model (SM) calculations. Several solutions have been proposed such as the introduction of non-factorizable terms and penguin-annihilation amplitudes, while other explanations invoke new physics. New modes have been investigated to shed more light on the problem.

Test of Understanding of Vectors: A Reliable Multiple-Choice Vector Concept Test

Science.gov (United States)

Barniol, Pablo; Zavala, Genaro

2014-01-01

In this article we discuss the findings of our research on students' understanding of vector concepts in problems without physical context. First, we develop a complete taxonomy of the most frequent errors made by university students when learning vector concepts. This study is based on the results of several test administrations of open-ended…

Local Patch Vectors Encoded by Fisher Vectors for Image Classification

Directory of Open Access Journals (Sweden)

Shuangshuang Chen

2018-02-01

Full Text Available The objective of this work is image classification, whose purpose is to group images into corresponding semantic categories. Four contributions are made as follows: (i For computational simplicity and efficiency, we directly adopt raw image patch vectors as local descriptors encoded by Fisher vector (FV subsequently; (ii For obtaining representative local features within the FV encoding framework, we compare and analyze three typical sampling strategies: random sampling, saliency-based sampling and dense sampling; (iii In order to embed both global and local spatial information into local features, we construct an improved spatial geometry structure which shows good performance; (iv For reducing the storage and CPU costs of high dimensional vectors, we adopt a new feature selection method based on supervised mutual information (MI, which chooses features by an importance sorting algorithm. We report experimental results on dataset STL-10. It shows very promising performance with this simple and efficient framework compared to conventional methods.

Vector-Vector Scattering on the Lattice

Science.gov (United States)

Romero-López, Fernando; Urbach, Carsten; Rusetsky, Akaki

2018-03-01

In this work we present an extension of the LüScher formalism to include the interaction of particles with spin, focusing on the scattering of two vector particles. The derived formalism will be applied to Scalar QED in the Higgs Phase, where the U(1) gauge boson acquires mass.

Conformal Killing vectors in Robertson-Walker spacetimes

International Nuclear Information System (INIS)

Maartens, R.; Maharaj, S.d.

1986-01-01

It is well known that Robertson-Walker spacetimes admit a conformal Killingl vector normal to the spacelike homogeneous hypersurfaces. Because these spacetimes are conformally flat, there are a further eight conformal Killing vectors, which are neither normal nor tangent to the homogeneous hypersurfaces. The authors find these further conformal Killing vectors and the Lie algebra of the full G 15 of conformal motions. Conditions on the metric scale factor are determined which reduce some of the conformal Killing vectors to homothetic Killing vectors or Killing vectors, allowing one to regain in a unified way the known special geometries. The non-normal conformal Killing vectors provide a counter-example to show that conformal motions do not, in general, map a fluid flow conformally. These non-normal vectors are also used to find the general solution of the null geodesic equation and photon Liouville equation. (author)

A generalized nonlocal vector calculus

Science.gov (United States)

Alali, Bacim; Liu, Kuo; Gunzburger, Max

2015-10-01

A nonlocal vector calculus was introduced in Du et al. (Math Model Meth Appl Sci 23:493-540, 2013) that has proved useful for the analysis of the peridynamics model of nonlocal mechanics and nonlocal diffusion models. A formulation is developed that provides a more general setting for the nonlocal vector calculus that is independent of particular nonlocal models. It is shown that general nonlocal calculus operators are integral operators with specific integral kernels. General nonlocal calculus properties are developed, including nonlocal integration by parts formula and Green's identities. The nonlocal vector calculus introduced in Du et al. (Math Model Meth Appl Sci 23:493-540, 2013) is shown to be recoverable from the general formulation as a special example. This special nonlocal vector calculus is used to reformulate the peridynamics equation of motion in terms of the nonlocal gradient operator and its adjoint. A new example of nonlocal vector calculus operators is introduced, which shows the potential use of the general formulation for general nonlocal models.

Broad patterns in domestic vector-borne Trypanosoma cruzi transmission dynamics: synanthropic animals and vector control.

Science.gov (United States)

Peterson, Jennifer K; Bartsch, Sarah M; Lee, Bruce Y; Dobson, Andrew P

2015-10-22

Chagas disease (caused by Trypanosoma cruzi) is the most important neglected tropical disease (NTD) in Latin America, infecting an estimated 5.7 million people in the 21 countries where it is endemic. It is one of the NTDs targeted for control and elimination by the 2020 London Declaration goals, with the first goal being to interrupt intra-domiciliary vector-borne T. cruzi transmission. A key question in domestic T. cruzi transmission is the role that synanthropic animals play in T. cruzi transmission to humans. Here, we ask, (1) do synanthropic animals need to be targeted in Chagas disease prevention policies?, and (2) how does the presence of animals affect the efficacy of vector control? We developed a simple mathematical model to simulate domestic vector-borne T. cruzi transmission and to specifically examine the interaction between the presence of synanthropic animals and effects of vector control. We used the model to explore how the interactions between triatomine bugs, humans and animals impact the number and proportion of T. cruzi-infected bugs and humans. We then examined how T. cruzi dynamics change when control measures targeting vector abundance are introduced into the system. We found that the presence of synanthropic animals slows the speed of T. cruzi transmission to humans, and increases the sensitivity of T. cruzi transmission dynamics to vector control measures at comparable triatomine carrying capacities. However, T. cruzi transmission is amplified when triatomine carrying capacity increases with the abundance of syntathoropic hosts. Our results suggest that in domestic T. cruzi transmission scenarios where no vector control measures are in place, a reduction in synanthropic animals may slow T. cruzi transmission to humans, but it would not completely eliminate transmission. To reach the 2020 goal of interrupting intra-domiciliary T. cruzi transmission, it is critical to target vector populations. Additionally, where vector control measures

Spin information from vector-meson decay in photoproduction

International Nuclear Information System (INIS)

Kloet, W.M.; Chiang, W.; Tabakin, F.

1998-01-01

For the photoproduction of vector mesons, all single and double spin observables involving vector-meson two-body decays are defined consistently in the γN center-of-mass frame. These definitions yield a procedure for extracting physically meaningful single and double spin observables that are subject to known rules concerning their angle and energy evolution. As part of this analysis, we show that measuring the two-meson decay of a photo produced ρ or φ does not determine the vector meson's vector polarization, but only its tensor polarization. The vector meson decay into lepton pairs is also insensitive to the vector meson's vector polarization, unless one measures the spin of one of the leptons. Similar results are found for all double spin observables which involve observation of vector-meson decay. To access the vector meson's vector polarization, one therefore needs to either measure the spin of the decay leptons, make an analysis of the background interference effects, or relate the vector meson's vector polarization to other accessible spin observables. copyright 1998 The American Physical Society

[Effects of plant viruses on vector and non-vector herbivorous arthropods and their natural enemies: a mini review].

Science.gov (United States)

He, Xiao-Chan; Xu, Hong-Xing; Zhou, Xiao-Jun; Zheng, Xu-Song; Sun, Yu-Jian; Yang, Ya-Jun; Tian, Jun-Ce; Lü, Zhong-Xian

2014-05-01

Plant viruses transmitted by arthropods, as an important biotic factor, may not only directly affect the yield and quality of host plants, and development, physiological characteristics and ecological performances of their vector arthropods, but also directly or indirectly affect the non-vector herbivorous arthropods and their natural enemies in the same ecosystem, thereby causing influences to the whole agro-ecosystem. This paper reviewed the progress on the effects of plant viruses on herbivorous arthropods, including vector and non-vector, and their natural enemies, and on their ecological mechanisms to provide a reference for optimizing the management of vector and non-vector arthropod populations and sustainable control of plant viruses in agro-ecosystem.

Renewal of radiological equipment.

Science.gov (United States)

2014-10-01

In this century, medical imaging is at the heart of medical practice. Besides providing fast and accurate diagnosis, advances in radiology equipment offer new and previously non-existing options for treatment guidance with quite low morbidity, resulting in the improvement of health outcomes and quality of life for the patients. Although rapid technological development created new medical imaging modalities and methods, the same progress speed resulted in accelerated technical and functional obsolescence of the same medical imaging equipment, consequently creating a need for renewal. Older equipment has a high risk of failures and breakdowns, which might cause delays in diagnosis and treatment of the patient, and safety problems both for the patient and the medical staff. The European Society of Radiology is promoting the use of up-to-date equipment, especially in the context of the EuroSafe Imaging Campaign, as the use of up-to-date equipment will improve quality and safety in medical imaging. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or renewal. This plan should look forward a minimum of 5 years, with annual updates. Teaching points • Radiological equipment has a definite life cycle span, resulting in unavoidable breakdown and decrease or loss of image quality which renders equipment useless after a certain time period.• Equipment older than 10 years is no longer state-of-the art equipment and replacement is essential. Operating costs of older equipment will be high when compared with new equipment, and sometimes maintenance will be impossible if no spare parts are available.• Older equipment has a high risk of failure and breakdown, causing delays in diagnosis and treatment of the patient and safety problems both for the patient and the medical staff.• Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or replacement. This plan should look forward a

Prediction of folding preference of 10 kDa silk-like proteins using a Lego approach and ab initio calculations.

Science.gov (United States)

Pohl, Gábor; Beke, Tamás; Borbély, János; Perczel, András

2006-11-15

Because of their great flexibility and strength resistance, both spider silks and silkworm silks are of increasing scientific and commercial interest. Despite numerous spectroscopic and theoretical studies, several structural properties at the atomic level have yet to be identified. The present theoretical investigation focuses on these issues by studying three silk-like model peptides: (AG)(64), [(AG)(4)EG](16), and [(AG)(4)PEG](16), using a Lego-type approach to construct these polypeptides. On the basis of these examples it is shown that thermoneutral isodesmic reactions and ab initio calculations provide a capable method to investigate structural properties of repetitive polypeptides. The most probable overall fold schema of these molecules with respect to the type of embedded hairpin structures were determined at the ab initio level of theory (RHF/6-311++G(d,p)//RHF/3-21G). Further on, analysis is carried out on the possible hairpin and turn regions and on their effect on the global fold. In the case of the (AG)(64) model peptide, the optimal beta-sheet/turn ratio was also determined, which provided good support for experimental observations. In addition, lateral shearing of a hairpin "folding unit" was investigated at the quantum chemical level to explain the mechanical properties of spider silk. The unique mechanical characteristics of silk bio-compounds are now investigated at the atomic level.

Virus-Vectored Influenza Virus Vaccines

Science.gov (United States)

Tripp, Ralph A.; Tompkins, S. Mark

2014-01-01

Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide. Constant evolution of circulating influenza virus strains and the emergence of new strains diminishes the effectiveness of annual vaccines that rely on a match with circulating influenza strains. Thus, there is a continued need for new, efficacious vaccines conferring cross-clade protection to avoid the need for biannual reformulation of seasonal influenza vaccines. Recombinant virus-vectored vaccines are an appealing alternative to classical inactivated vaccines because virus vectors enable native expression of influenza antigens, even from virulent influenza viruses, while expressed in the context of the vector that can improve immunogenicity. In addition, a vectored vaccine often enables delivery of the vaccine to sites of inductive immunity such as the respiratory tract enabling protection from influenza virus infection. Moreover, the ability to readily manipulate virus vectors to produce novel influenza vaccines may provide the quickest path toward a universal vaccine protecting against all influenza viruses. This review will discuss experimental virus-vectored vaccines for use in humans, comparing them to licensed vaccines and the hurdles faced for licensure of these next-generation influenza virus vaccines. PMID:25105278

Vector Boson Scattering at High Mass

CERN Document Server

The ATLAS collaboration

2009-01-01

In the absence of a light Higgs boson, the mechanism of electroweak symmetry breaking will be best studied in processes of vector boson scattering at high mass. Various models predict resonances in this channel. Here, we investigate $WW $scalar and vector resonances, $WZ$ vector resonances and a $ZZ$ scalar resonance over a range of diboson centre-of-mass energies. Particular attention is paid to the application of forward jet tagging and to the reconstruction of dijet pairs with low opening angle resulting from the decay of highly boosted vector bosons. The performances of different jet algorithms are compared. We find that resonances in vector boson scattering can be discovered with a few tens of inverse femtobarns of integrated luminosity.

Symmetric vectors and algebraic classification

International Nuclear Information System (INIS)

Leibowitz, E.

1980-01-01

The concept of symmetric vector field in Riemannian manifolds, which arises in the study of relativistic cosmological models, is analyzed. Symmetric vectors are tied up with the algebraic properties of the manifold curvature. A procedure for generating a congruence of symmetric fields out of a given pair is outlined. The case of a three-dimensional manifold of constant curvature (''isotropic universe'') is studied in detail, with all its symmetric vector fields being explicitly constructed

Realization of logical functions by vector programs

Energy Technology Data Exchange (ETDEWEB)

Lapkin, L Ya

1983-03-01

Recent computing and control applications often require program realization of finite automata in general and of an important particular class of memoryless automata specified by systems of Boolean functions. Logical control and computing machines which receive sequences of discrete signals on the input and convert them into sequences of discrete output signals using finite memory may be described by a finite automation model. However, in distinction from the circuit interpretation of finite automata, the automaton algorithm represents the structure of the automaton program and not the structure of the machine itself. Therefore, the complexity of the computer realization of an automaton is the complexity of the computer program, and not the complexity of the hardware. Two classes of programs currently used to evalute boolean functions are operator programs and binary programs. However, computing machines, including microcomputers, are equipped with additional possibilities for evaluation of Boolean functions, which are not utilized in programs of these two basic classes. In this article, we consider the design of vector programs for program realization of systems of Boolean functions. 3 references.

[New strategy for RNA vectorization in mammalian cells. Use of a peptide vector].

Science.gov (United States)

Vidal, P; Morris, M C; Chaloin, L; Heitz, F; Divita, G

1997-04-01

A major barrier for gene delivery is the low permeability of nucleic acids to cellular membranes. The development of antisenses and gene therapy has focused mainly on improving methods of oligonucleotide or gene delivery to the cell. In this report we described a new strategy for RNA cell delivery, based on a short single peptide. This peptide vector is derived from both the fusion domain of the gp41 protein of HIV and the nuclear localization sequence of the SV40 large T antigen. This peptide vector localizes rapidly to the cytoplasm then to the nucleus of human fibroblasts (HS-68) within a few minutes and exhibits a high affinity for a single-stranded mRNA encoding the p66 subunit of the HIV-1 reverse transcriptase (in a 100 nM range). The peptide/RNA complex formation involves mainly electrostatic interactions between the basic residues of the peptide and the charges on the phosphate group of the RNA. In the presence of the peptide-vector fluorescently-labelled mRNA is delivered into the cytoplasm of mammalian cells (HS68 human fibroblasts) in less than 1 h with a relatively high efficiency (80%). This new concept based on a peptide-derived vector offers several advantages compared to other compounds commonly used in gene delivery. This vector is highly soluble and exhibits no cytotoxicity at the concentrations used for optimal gene delivery. This result clearly supports the fact that this peptide vector is a powerful tool and that it can be used widely, as much for laboratory research as for new applications and development in gene and/or antisense therapy.

Attenuated Vector Tomography -- An Approach to Image Flow Vector Fields with Doppler Ultrasonic Imaging

International Nuclear Information System (INIS)

Huang, Qiu; Peng, Qiyu; Huang, Bin; Cheryauka, Arvi; Gullberg, Grant T.

2008-01-01

The measurement of flow obtained using continuous wave Doppler ultrasound is formulated as a directional projection of a flow vector field. When a continuous ultrasound wave bounces against a flowing particle, a signal is backscattered. This signal obtains a Doppler frequency shift proportional to the speed of the particle along the ultrasound beam. This occurs for each particle along the beam, giving rise to a Doppler velocity spectrum. The first moment of the spectrum provides the directional projection of the flow along the ultrasound beam. Signals reflected from points further away from the detector will have lower amplitude than signals reflected from points closer to the detector. The effect is very much akin to that modeled by the attenuated Radon transform in emission computed tomography.A least-squares method was adopted to reconstruct a 2D vector field from directional projection measurements. Attenuated projections of only the longitudinal projections of the vector field were simulated. The components of the vector field were reconstructed using the gradient algorithm to minimize a least-squares criterion. This result was compared with the reconstruction of longitudinal projections of the vector field without attenuation. If attenuation is known, the algorithm was able to accurately reconstruct both components of the full vector field from only one set of directional projection measurements. A better reconstruction was obtained with attenuation than without attenuation implying that attenuation provides important information for the reconstruction of flow vector fields.This confirms previous work where we showed that knowledge of the attenuation distribution helps in the reconstruction of MRI diffusion tensor fields from fewer than the required measurements. In the application of ultrasound the attenuation distribution is obtained with pulse wave transmission computed tomography and flow information is obtained with continuous wave Doppler

Organizational Learning with Crowdsourcing

DEFF Research Database (Denmark)

Schlagwein, Daniel; Bjørn-Andersen, Niels

2014-01-01

, a form of open innovation enabled by state-of-the-art IT. We examine the phenomenon of IT-enabled organizational learning with crowdsourcing in a longitudinal revelatory case study of one such organization, LEGO (2010-14). We studied the LEGO Cuusoo crowdsourcing platform’s secret test in Japan, its...... widely recognized global launch, and its success in generating top-selling LEGO models. Based on an analysis of how crowdsourcing contributes to the organizational learning at LEGO, we propose the “ambient organizational learning” framework. The framework accommodates both traditional, member...

40 CFR 503.33 - Vector attraction reduction.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Vector attraction reduction. 503.33... STANDARDS FOR THE USE OR DISPOSAL OF SEWAGE SLUDGE Pathogens and Vector Attraction Reduction § 503.33 Vector attraction reduction. (a)(1) One of the vector attraction reduction requirements in § 503.33 (b)(1) through...

Vector Boson Scattering at High Mass

CERN Document Server

Sherwood, P

2009-01-01

In the absence of a light Higgs boson, the mechanism of electroweak symmetry breaking will be best studied in processes of vector boson scattering at high mass. Various models predict resonances in this channel. Here, we investigate W W scalar and vector resonances, W Z vector resonances and a Z Z scalar resonance over a range of diboson centre-of-mass energies. Particular attention is paid to the application reconstruction of dijet pairs with low opening angle resulting from the decay of highly boosted vector bosons.

Optimality Conditions in Vector Optimization

CERN Document Server

Jiménez, Manuel Arana; Lizana, Antonio Rufián

2011-01-01

Vector optimization is continuously needed in several science fields, particularly in economy, business, engineering, physics and mathematics. The evolution of these fields depends, in part, on the improvements in vector optimization in mathematical programming. The aim of this Ebook is to present the latest developments in vector optimization. The contributions have been written by some of the most eminent researchers in this field of mathematical programming. The Ebook is considered essential for researchers and students in this field.

Multineuronal vectorization is more efficient than time-segmental vectorization for information extraction from neuronal activities in the inferior temporal cortex.

Science.gov (United States)

Kaneko, Hidekazu; Tamura, Hiroshi; Tate, Shunta; Kawashima, Takahiro; Suzuki, Shinya S; Fujita, Ichiro

2010-08-01

In order for patients with disabilities to control assistive devices with their own neural activity, multineuronal spike trains must be efficiently decoded because only limited computational resources can be used to generate prosthetic control signals in portable real-time applications. In this study, we compare the abilities of two vectorizing procedures (multineuronal and time-segmental) to extract information from spike trains during the same total neuron-seconds. In the multineuronal vectorizing procedure, we defined a response vector whose components represented the spike counts of one to five neurons. In the time-segmental vectorizing procedure, a response vector consisted of components representing a neuron's spike counts for one to five time-segment(s) of a response period of 1 s. Spike trains were recorded from neurons in the inferior temporal cortex of monkeys presented with visual stimuli. We examined whether the amount of information of the visual stimuli carried by these neurons differed between the two vectorizing procedures. The amount of information calculated with the multineuronal vectorizing procedure, but not the time-segmental vectorizing procedure, significantly increased with the dimensions of the response vector. We conclude that the multineuronal vectorizing procedure is superior to the time-segmental vectorizing procedure in efficiently extracting information from neuronal signals. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Adenoviral vector immunity: its implications and circumvention strategies.

Science.gov (United States)

Ahi, Yadvinder S; Bangari, Dinesh S; Mittal, Suresh K

2011-08-01

Adenoviral (Ad) vectors have emerged as a promising gene delivery platform for a variety of therapeutic and vaccine purposes during last two decades. However, the presence of preexisting Ad immunity and the rapid development of Ad vector immunity still pose significant challenges to the clinical use of these vectors. Innate inflammatory response following Ad vector administration may lead to systemic toxicity, drastically limit vector transduction efficiency and significantly abbreviate the duration of transgene expression. Currently, a number of approaches are being extensively pursued to overcome these drawbacks by strategies that target either the host or the Ad vector. In addition, significant progress has been made in the development of novel Ad vectors based on less prevalent human Ad serotypes and nonhuman Ad. This review provides an update on our current understanding of immune responses to Ad vectors and delineates various approaches for eluding Ad vector immunity. Approaches targeting the host and those targeting the vector are discussed in light of their promises and limitations.

A Subdivision-Based Representation for Vector Image Editing.

Science.gov (United States)

Liao, Zicheng; Hoppe, Hugues; Forsyth, David; Yu, Yizhou

2012-11-01

Vector graphics has been employed in a wide variety of applications due to its scalability and editability. Editability is a high priority for artists and designers who wish to produce vector-based graphical content with user interaction. In this paper, we introduce a new vector image representation based on piecewise smooth subdivision surfaces, which is a simple, unified and flexible framework that supports a variety of operations, including shape editing, color editing, image stylization, and vector image processing. These operations effectively create novel vector graphics by reusing and altering existing image vectorization results. Because image vectorization yields an abstraction of the original raster image, controlling the level of detail of this abstraction is highly desirable. To this end, we design a feature-oriented vector image pyramid that offers multiple levels of abstraction simultaneously. Our new vector image representation can be rasterized efficiently using GPU-accelerated subdivision. Experiments indicate that our vector image representation achieves high visual quality and better supports editing operations than existing representations.

Generalized Selection Weighted Vector Filters

Directory of Open Access Journals (Sweden)

Rastislav Lukac

2004-09-01

Full Text Available This paper introduces a class of nonlinear multichannel filters capable of removing impulsive noise in color images. The here-proposed generalized selection weighted vector filter class constitutes a powerful filtering framework for multichannel signal processing. Previously defined multichannel filters such as vector median filter, basic vector directional filter, directional-distance filter, weighted vector median filters, and weighted vector directional filters are treated from a global viewpoint using the proposed framework. Robust order-statistic concepts and increased degree of freedom in filter design make the proposed method attractive for a variety of applications. Introduced multichannel sigmoidal adaptation of the filter parameters and its modifications allow to accommodate the filter parameters to varying signal and noise statistics. Simulation studies reported in this paper indicate that the proposed filter class is computationally attractive, yields excellent performance, and is able to preserve fine details and color information while efficiently suppressing impulsive noise. This paper is an extended version of the paper by Lukac et al. presented at the 2003 IEEE-EURASIP Workshop on Nonlinear Signal and Image Processing (NSIP '03 in Grado, Italy.

Production of lentiviral vectors

Directory of Open Access Journals (Sweden)

Otto-Wilhelm Merten

2016-01-01

Full Text Available Lentiviral vectors (LV have seen considerably increase in use as gene therapy vectors for the treatment of acquired and inherited diseases. This review presents the state of the art of the production of these vectors with particular emphasis on their large-scale production for clinical purposes. In contrast to oncoretroviral vectors, which are produced using stable producer cell lines, clinical-grade LV are in most of the cases produced by transient transfection of 293 or 293T cells grown in cell factories. However, more recent developments, also, tend to use hollow fiber reactor, suspension culture processes, and the implementation of stable producer cell lines. As is customary for the biotech industry, rather sophisticated downstream processing protocols have been established to remove any undesirable process-derived contaminant, such as plasmid or host cell DNA or host cell proteins. This review compares published large-scale production and purification processes of LV and presents their process performances. Furthermore, developments in the domain of stable cell lines and their way to the use of production vehicles of clinical material will be presented.

Inverse Operation of Four-dimensional Vector Matrix

OpenAIRE

H J Bao; A J Sang; H X Chen

2011-01-01

This is a new series of study to define and prove multidimensional vector matrix mathematics, which includes four-dimensional vector matrix determinant, four-dimensional vector matrix inverse and related properties. There are innovative concepts of multi-dimensional vector matrix mathematics created by authors with numerous applications in engineering, math, video conferencing, 3D TV, and other fields.

Multiscale vector fields for image pattern recognition

Science.gov (United States)

Low, Kah-Chan; Coggins, James M.

1990-01-01

A uniform processing framework for low-level vision computing in which a bank of spatial filters maps the image intensity structure at each pixel into an abstract feature space is proposed. Some properties of the filters and the feature space are described. Local orientation is measured by a vector sum in the feature space as follows: each filter's preferred orientation along with the strength of the filter's output determine the orientation and the length of a vector in the feature space; the vectors for all filters are summed to yield a resultant vector for a particular pixel and scale. The orientation of the resultant vector indicates the local orientation, and the magnitude of the vector indicates the strength of the local orientation preference. Limitations of the vector sum method are discussed. Investigations show that the processing framework provides a useful, redundant representation of image structure across orientation and scale.

Vector control of induction machines

CERN Document Server

Robyns, Benoit

2012-01-01

After a brief introduction to the main law of physics and fundamental concepts inherent in electromechanical conversion, ""Vector Control of Induction Machines"" introduces the standard mathematical models for induction machines - whichever rotor technology is used - as well as several squirrel-cage induction machine vector-control strategies. The use of causal ordering graphs allows systematization of the design stage, as well as standardization of the structure of control devices. ""Vector Control of Induction Machines"" suggests a unique approach aimed at reducing parameter sensitivity for

Morphological, structural, thermal, compositional, vibrational, and pasting characterization of white, yellow, and purple Arracacha Lego-like starches and flours (Arracacia xanthorrhiza).

Science.gov (United States)

Londoño-Restrepo, Sandra M; Rincón-Londoño, Natalia; Contreras-Padilla, Margarita; Millan-Malo, Beatriz M; Rodriguez-Garcia, Mario E

2018-07-01

This work is focused on the chemical, structural, morphological, thermal, IR vibrational, and pasting characterization of isolated white, yellow, and purple Arracacha starches from Colombia. Inductive couple plasma showed that these starches are rich in potassium. Scanning Electron Microscopy (SEM) images show that the starch granules are formed by ovoid fully filled Lego-like starch microparticles, the circular cross-section has a diameter between 9 and 15μm and mayor axis between 20 and 30μm. Each one of these ovoids is formed by irregular wedge-shaped 6 to 10 isolated starch granules with an average size between 4 and 12μm. The amylose content ranged between 31 and 36%. Arracacha starches exhibited high viscosity values (between 20.000 and 28.000cP), which could be influenced by the high content of potassium ions, due to the C-H~K Van Der Waals interaction that was identified by using IR spectroscopy. According to the X-ray diffraction analysis, the starch patterns exhibited broad diffracted peaks which could be associated with the existence of nano-crystals and lamellae; the Differential Scanning calorimetry (DSC) result showed starches with a low gelatinization temperature of about 60°C. Copyright © 2018 Elsevier B.V. All rights reserved.

Viral vector-based influenza vaccines

Science.gov (United States)

de Vries, Rory D.; Rimmelzwaan, Guus F.

2016-01-01

ABSTRACT Antigenic drift of seasonal influenza viruses and the occasional introduction of influenza viruses of novel subtypes into the human population complicate the timely production of effective vaccines that antigenically match the virus strains that cause epidemic or pandemic outbreaks. The development of game-changing vaccines that induce broadly protective immunity against a wide variety of influenza viruses is an unmet need, in which recombinant viral vectors may provide. Use of viral vectors allows the delivery of any influenza virus antigen, or derivative thereof, to the immune system, resulting in the optimal induction of virus-specific B- and T-cell responses against this antigen of choice. This systematic review discusses results obtained with vectored influenza virus vaccines and advantages and disadvantages of the currently available viral vectors. PMID:27455345

Integrated optic vector-matrix multiplier

Science.gov (United States)

Watts, Michael R [Albuquerque, NM

2011-09-27

A vector-matrix multiplier is disclosed which uses N different wavelengths of light that are modulated with amplitudes representing elements of an N.times.1 vector and combined to form an input wavelength-division multiplexed (WDM) light stream. The input WDM light stream is split into N streamlets from which each wavelength of the light is individually coupled out and modulated for a second time using an input signal representing elements of an M.times.N matrix, and is then coupled into an output waveguide for each streamlet to form an output WDM light stream which is detected to generate a product of the vector and matrix. The vector-matrix multiplier can be formed as an integrated optical circuit using either waveguide amplitude modulators or ring resonator amplitude modulators.

3D vector flow imaging

DEFF Research Database (Denmark)

Pihl, Michael Johannes

The main purpose of this PhD project is to develop an ultrasonic method for 3D vector flow imaging. The motivation is to advance the field of velocity estimation in ultrasound, which plays an important role in the clinic. The velocity of blood has components in all three spatial dimensions, yet...... are (vx, vy, vz) = (-0.03, 95, 1.0) ± (9, 6, 1) cm/s compared with the expected (0, 96, 0) cm/s. Afterwards, 3D vector flow images from a cross-sectional plane of the vessel are presented. The out of plane velocities exhibit the expected 2D circular-symmetric parabolic shape. The experimental results...... verify that the 3D TO method estimates the complete 3D velocity vectors, and that the method is suitable for 3D vector flow imaging....

Problems and worked solutions in vector analysis

CERN Document Server

Shorter, LR

2014-01-01

""A handy book like this,"" noted The Mathematical Gazette, ""will fill a great want."" Devoted to fully worked out examples, this unique text constitutes a self-contained introductory course in vector analysis for undergraduate and graduate students of applied mathematics.Opening chapters define vector addition and subtraction, show how to resolve and determine the direction of two or more vectors, and explain systems of coordinates, vector equations of a plane and straight line, relative velocity and acceleration, and infinitely small vectors. The following chapters deal with scalar and vect

An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector

Directory of Open Access Journals (Sweden)

Vreugdenhil Erno

2010-07-01

Full Text Available Abstract Background This study compared the transduction efficiencies of an adeno-associated viral (AAV vector, which was pseudotyped with an AAV1 capsid and encoded the green fluorescent protein (GFP, with a lentiviral (LV vector, which was pseudotyped with a VSV-G envelop and encoded the discosoma red fluorescent protein (dsRed, to investigate which viral vector transduced the lateral hypothalamus or the amygdala more efficiently. The LV-dsRed and AAV1-GFP vector were mixed and injected into the lateral hypothalamus or into the amygdala of adult rats. The titers that were injected were 1 × 108 or 1 × 109 genomic copies of AAV1-GFP and 1 × 105 transducing units of LV-dsRed. Results Immunostaining for GFP and dsRed showed that AAV1-GFP transduced significantly more cells than LV-dsRed in both the lateral hypothalamus and the amygdala. In addition, the number of LV particles that were injected can not easily be increased, while the number of AAV1 particles can be increased easily with a factor 100 to 1000. Both viral vectors appear to predominantly transduce neurons. Conclusions This study showed that AAV1 vectors are better tools to overexpress or knockdown genes in the lateral hypothalamus and amygdala of adult rats, since more cells can be transduced with AAV1 than with LV vectors and the titer of AAV1 vectors can easily be increased to transduce the area of interest.

Gauge structure of neutral-vector field theory. [Massive vector fields, massless limits

Energy Technology Data Exchange (ETDEWEB)

Kubo, R; Yokoyama, [Hiroshima univ., Takehara (Japan). Research Inst. for Theoretical Physics

1975-03-01

General aspects of gauge structure of neutral-vector field theory are investigated from an extended standpoint, where massive vector fields are treated in a form corresponding to the electromagnetic fields in a general gauge formalism reported previously. All results obtained are shown to have unique massless limits. It is shown that a generalized q-number gauge transformation for fields makes the theory invariant in cooperation with a simultaneous transformation for relevant gauge parameters. A method of differentiation with respect to a gauge variable is found to clarify some essential features of the gauge structure. Two possible types of gauge structure also emerge correspondingly to the massless case. A neutral-vector field theory proposed in a preceding paper is included in the present framework as the most preferable case.

29 CFR 97.32 - Equipment.

Science.gov (United States)

2010-07-01

...) When acquiring replacement equipment, the grantee or subgrantee may use the equipment to be replaced as... equipment (including replacement equipment), whether acquired in whole or in part with grant funds, until... established to ensure the highest possible return. (e) Disposition. When original or replacement equipment...

44 CFR 13.32 - Equipment.

Science.gov (United States)

2010-10-01

...) When acquiring replacement equipment, the grantee or subgrantee may use the equipment to be replaced as... equipment (including replacement equipment), whether acquired in whole or in part with grant funds, until... established to ensure the highest possible return. (e) Disposition. When original or replacement equipment...

24 CFR 85.32 - Equipment.

Science.gov (United States)

2010-04-01

...) When acquiring replacement equipment, the grantee or subgrantee may use the equipment to be replaced as... equipment (including replacement equipment), whether acquired in whole or in part with grant funds, until... established to ensure the highest possible return. (e) Disposition. When original or replacement equipment...

43 CFR 12.72 - Equipment.

Science.gov (United States)

2010-10-01

...) When acquiring replacement equipment, the grantee or subgrantee may use the equipment to be replaced as... equipment (including replacement equipment), whether acquired in whole or in part with grant funds, until... established to ensure the highest possible return. (e) Disposition. When original or replacement equipment...

Civil Justice: Lay Judges in the EU Countries

Directory of Open Access Journals (Sweden)

Stefan Machura

2016-06-01

Full Text Available Lay judges fulfill important functions for the justice system of a country. In the European Union member states, scholars have analysed the use of lay judges in criminal cases. However, little is known about lay participation in civil justice. The paper introduces commonly cited reasons to have lay judges as well as the principal forms of lay participation and then surveys the EU countries for its implementation in civil cases. Mixed tribunals, involving lay judges under the leadership of a professional judge, are relatively frequent. Several countries have special labour courts or commercial courts with lay members and others have single lay judges, or all-lay judge panels. Roughly a third of the 28 EU member states have no lay participation in civil justice but only three of those have no lay judges in any branch of the courts. Almost all the reasons for including lay decision makers are served somehow by the existing forms, including providing different experiences and perhaps expert knowledge. The article concludes, citing non-EU states and lay participation in criminal and administrative courts as further evidence, that lay judges in one form or another are an element of European legal systems. Los jueces legos cumplen funciones importantes para el sistema de justicia de un país. En los Estados miembro de la Unión Europea, académicos han analizado el uso de jueces legos en casos criminales. Sin embargo, se sabe poco acerca de la participación de los legos en la justicia civil. El artículo presenta las razones que habitualmente se citan para tener jueces legos, así como las formas principales de la participación de legos, para a continuación medir su implementación en casos civiles en los países de la Unión Europea. Son relativamente frecuentes los tribunales mixtos, en los que participan jueces legos, bajo la dirección de un juez profesional. Varios países tienen tribunales laborales especiales o tribunales comerciales con

Matrix vector analysis

CERN Document Server

Eisenman, Richard L

2005-01-01

This outstanding text and reference applies matrix ideas to vector methods, using physical ideas to illustrate and motivate mathematical concepts but employing a mathematical continuity of development rather than a physical approach. The author, who taught at the U.S. Air Force Academy, dispenses with the artificial barrier between vectors and matrices--and more generally, between pure and applied mathematics.Motivated examples introduce each idea, with interpretations of physical, algebraic, and geometric contexts, in addition to generalizations to theorems that reflect the essential structur

Declining Prevalence of Disease Vectors Under Climate Change

Science.gov (United States)

Escobar, Luis E.; Romero-Alvarez, Daniel; Leon, Renato; Lepe-Lopez, Manuel A.; Craft, Meggan E.; Borbor-Cordova, Mercy J.; Svenning, Jens-Christian

2016-12-01

More than half of the world population is at risk of vector-borne diseases including dengue fever, chikungunya, zika, yellow fever, leishmaniasis, chagas disease, and malaria, with highest incidences in tropical regions. In Ecuador, vector-borne diseases are present from coastal and Amazonian regions to the Andes Mountains; however, a detailed characterization of the distribution of their vectors has never been carried out. We estimate the distribution of 14 vectors of the above vector-borne diseases under present-day and future climates. Our results consistently suggest that climate warming is likely threatening some vector species with extinction, locally or completely. These results suggest that climate change could reduce the burden of specific vector species. Other vector species are likely to shift and constrain their geographic range to the highlands in Ecuador potentially affecting novel areas and populations. These forecasts show the need for development of early prevention strategies for vector species currently absent in areas projected as suitable under future climate conditions. Informed interventions could reduce the risk of human exposure to vector species with distributional shifts, in response to current and future climate changes. Based on the mixed effects of future climate on human exposure to disease vectors, we argue that research on vector-borne diseases should be cross-scale and include climatic, demographic, and landscape factors, as well as forces facilitating disease transmission at fine scales.

Vector boson scattering at CLIC

Energy Technology Data Exchange (ETDEWEB)

Kilian, Wolfgang; Fleper, Christian [Department Physik, Universitaet Siegen, 57068 Siegen (Germany); Reuter, Juergen [DESY Theory Group, 22603 Hamburg (Germany); Sekulla, Marco [Institut fuer Theoretische Physik, Karlsruher Institut fuer Technologie, 76131 Karlsruhe (Germany)

2016-07-01

Linear colliders operating in a range of multiple TeV are able to investigate the details of vector boson scattering and electroweak symmetry breaking. We calculate cross sections with the Monte Carlo generator WHIZARD for vector boson scattering processes at the future linear e{sup +} e{sup -} collider CLIC. By finding suitable cuts, the vector boson scattering signal processes are isolated from the background. Finally, we are able to determine exclusion sensitivities on the non-Standard Model parameters of the relevant dimension eight operators.

LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors.

Science.gov (United States)

Tung, Truong-Thanh; Dao, Trong T; Junyent, Marta G; Palmgren, Michael; Günther-Pomorski, Thomas; Fuglsang, Anja T; Christensen, Søren B; Nielsen, John

2018-01-08

The fungal plasma membrane H + -ATPase (Pma1p) is a potential target for the discovery of new antifungal agents. Surprisingly, no structure-activity relationship studies for small molecules targeting Pma1p have been reported. Herein, we disclose a LEGO-inspired fragment assembly strategy for the design, synthesis, and discovery of benzo[d]thiazoles containing a 3,4-dihydroxyphenyl moiety as potential Pma1p inhibitors. A series of 2-(benzo[d]thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanones was found to inhibit Pma1p, with the most potent IC 50 value of 8 μm in an in vitro plasma membrane H + -ATPase assay. These compounds were also found to strongly inhibit the action of proton pumping when Pma1p was reconstituted into liposomes. 1-(3,4-Dihydroxyphenyl)-2-((6-(trifluoromethyl)benzo[d]thiazol-2-yl)thio)ethan-1-one (compound 38) showed inhibitory activities on the growth of Candida albicans and Saccharomyces cerevisiae, which could be correlated and substantiated with the ability to inhibit Pma1p in vitro. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Decays of the vector glueball

Science.gov (United States)

Giacosa, Francesco; Sammet, Julia; Janowski, Stanislaus

2017-06-01

We calculate two- and three-body decays of the (lightest) vector glueball into (pseudo)scalar, (axial-)vector, as well as pseudovector and excited vector mesons in the framework of a model of QCD. While absolute values of widths cannot be predicted because the corresponding coupling constants are unknown, some interesting branching ratios can be evaluated by setting the mass of the yet hypothetical vector glueball to 3.8 GeV as predicted by quenched lattice QCD. We find that the decay mode ω π π should be one of the largest (both through the decay chain O →b1π →ω π π and through the direct coupling O →ω π π ). Similarly, the (direct and indirect) decay into π K K*(892 ) is sizable. Moreover, the decays into ρ π and K*(892 )K are, although subleading, possible and could play a role in explaining the ρ π puzzle of the charmonium state ψ (2 S ) thanks to a (small) mixing with the vector glueball. The vector glueball can be directly formed at the ongoing BESIII experiment as well as at the future PANDA experiment at the FAIR facility. If the width is sufficiently small (≲100 MeV ) it should not escape future detection. It should be stressed that the employed model is based on some inputs and simplifying assumptions: the value of glueball mass (at present, the quenched lattice value is used), the lack of mixing of the glueball with other quarkonium states, and the use of few interaction terms. It then represents a first step toward the identification of the main decay channels of the vector glueball, but shall be improved when corresponding experimental candidates and/or new lattice results will be available.

Virtual-vector-based space vector pulse width modulation of the DC-AC multilevel-clamped multilevel converter (MLC²)

DEFF Research Database (Denmark)

Rodriguez, Pedro; Busquets-Monge, Sergio; Blaabjerg, Frede

2011-01-01

This work presents the development of the space vector pulse width modulation (SVPWM) of a new multi-level converter topology. First, the proposed converter and its natural space vector diagram are presented. Secondly, a modified space vector diagram based on the virtual-vectors technique is show...

Image Coding Based on Address Vector Quantization.

Science.gov (United States)

Feng, Yushu

Image coding is finding increased application in teleconferencing, archiving, and remote sensing. This thesis investigates the potential of Vector Quantization (VQ), a relatively new source coding technique, for compression of monochromatic and color images. Extensions of the Vector Quantization technique to the Address Vector Quantization method have been investigated. In Vector Quantization, the image data to be encoded are first processed to yield a set of vectors. A codeword from the codebook which best matches the input image vector is then selected. Compression is achieved by replacing the image vector with the index of the code-word which produced the best match, the index is sent to the channel. Reconstruction of the image is done by using a table lookup technique, where the label is simply used as an address for a table containing the representative vectors. A code-book of representative vectors (codewords) is generated using an iterative clustering algorithm such as K-means, or the generalized Lloyd algorithm. A review of different Vector Quantization techniques are given in chapter 1. Chapter 2 gives an overview of codebook design methods including the Kohonen neural network to design codebook. During the encoding process, the correlation of the address is considered and Address Vector Quantization is developed for color image and monochrome image coding. Address VQ which includes static and dynamic processes is introduced in chapter 3. In order to overcome the problems in Hierarchical VQ, Multi-layer Address Vector Quantization is proposed in chapter 4. This approach gives the same performance as that of the normal VQ scheme but the bit rate is about 1/2 to 1/3 as that of the normal VQ method. In chapter 5, a Dynamic Finite State VQ based on a probability transition matrix to select the best subcodebook to encode the image is developed. In chapter 6, a new adaptive vector quantization scheme, suitable for color video coding, called "A Self -Organizing

Transcriptional Silencing of Retroviral Vectors

DEFF Research Database (Denmark)

Lund, Anders Henrik; Duch, M.; Pedersen, F.S.

1996-01-01

. Extinction of long-term vector expression has been observed after implantation of transduced hematopoietic cells as well as fibroblasts, myoblasts and hepatocytes. Here we review the influence of vector structure, integration site and cell type on transcriptional silencing. While down-regulation of proviral...... transcription is known from a number of cellular and animal models, major insight has been gained from studies in the germ line and embryonal cells of the mouse. Key elements for the transfer and expression of retroviral vectors, such as the viral transcriptional enhancer and the binding site for the t......RNA primer for reverse transcription may have a major influence on transcriptional silencing. Alterations of these elements of the vector backbone as well as the use of internal promoter elements from housekeeping genes may contribute to reduce transcriptional silencing. The use of cell culture and animal...

Estimation of pure autoregressive vector models for revenue series ...

African Journals Online (AJOL)

This paper aims at applying multivariate approach to Box and Jenkins univariate time series modeling to three vector series. General Autoregressive Vector Models with time varying coefficients are estimated. The first vector is a response vector, while others are predictor vectors. By matrix expansion each vector, whether ...

On the Witt vector Frobenius

DEFF Research Database (Denmark)

Davis, Christopher James; Kedlaya, Kiran

2014-01-01

We study the kernel and cokernel of the Frobenius map on the p-typical Witt vectors of a commutative ring, not necessarily of characteristic p. We give many equivalent conditions to surjectivity of the Frobenius map on both finite and infinite length Witt vectors. In particular, surjectivity...... on finite Witt vectors turns out to be stable under certain integral extensions; this provides a clean formulation of a strong generalization of Faltings’s almost purity theorem from p-adic Hodge theory, incorporating recent improvements by Kedlaya–Liu and by Scholze....

Design and Potential of Non-Integrating Lentiviral Vectors

Directory of Open Access Journals (Sweden)

Aaron Shaw

2014-01-01

Full Text Available Lentiviral vectors have demonstrated promising results in clinical trials that target cells of the hematopoietic system. For these applications, they are the vectors of choice since they provide stable integration into cells that will undergo extensive expansion in vivo. Unfortunately, integration can have unintended consequences including dysregulated cell growth. Therefore, lentiviral vectors that do not integrate are predicted to have a safer profile compared to integrating vectors and should be considered for applications where transient expression is required or for sustained episomal expression such as in quiescent cells. In this review, the system for generating lentiviral vectors will be described and used to illustrate how alterations in the viral integrase or vector Long Terminal Repeats have been used to generate vectors that lack the ability to integrate. In addition to their safety advantages, these non-integrating lentiviral vectors can be used when persistent expression would have adverse consequences. Vectors are currently in development for use in vaccinations, cancer therapy, site-directed gene insertions, gene disruption strategies, and cell reprogramming. Preclinical work will be described that illustrates the potential of this unique vector system in human gene therapy.

Remote handling equipment

International Nuclear Information System (INIS)

Clement, G.

1984-01-01

After a definition of intervention, problems encountered for working in an adverse environment are briefly analyzed for development of various remote handling equipments. Some examples of existing equipments are given [fr

Archimedeanization of ordered vector spaces

OpenAIRE

Emelyanov, Eduard Yu.

2014-01-01

In the case of an ordered vector space with an order unit, the Archimedeanization method has been developed recently by V.I Paulsen and M. Tomforde. We present a general version of the Archimedeanization which covers arbitrary ordered vector spaces.

How random is a random vector?

International Nuclear Information System (INIS)

Eliazar, Iddo

2015-01-01

Over 80 years ago Samuel Wilks proposed that the “generalized variance” of a random vector is the determinant of its covariance matrix. To date, the notion and use of the generalized variance is confined only to very specific niches in statistics. In this paper we establish that the “Wilks standard deviation” –the square root of the generalized variance–is indeed the standard deviation of a random vector. We further establish that the “uncorrelation index” –a derivative of the Wilks standard deviation–is a measure of the overall correlation between the components of a random vector. Both the Wilks standard deviation and the uncorrelation index are, respectively, special cases of two general notions that we introduce: “randomness measures” and “independence indices” of random vectors. In turn, these general notions give rise to “randomness diagrams”—tangible planar visualizations that answer the question: How random is a random vector? The notion of “independence indices” yields a novel measure of correlation for Lévy laws. In general, the concepts and results presented in this paper are applicable to any field of science and engineering with random-vectors empirical data.

How random is a random vector?

Science.gov (United States)

Eliazar, Iddo

2015-12-01

Over 80 years ago Samuel Wilks proposed that the "generalized variance" of a random vector is the determinant of its covariance matrix. To date, the notion and use of the generalized variance is confined only to very specific niches in statistics. In this paper we establish that the "Wilks standard deviation" -the square root of the generalized variance-is indeed the standard deviation of a random vector. We further establish that the "uncorrelation index" -a derivative of the Wilks standard deviation-is a measure of the overall correlation between the components of a random vector. Both the Wilks standard deviation and the uncorrelation index are, respectively, special cases of two general notions that we introduce: "randomness measures" and "independence indices" of random vectors. In turn, these general notions give rise to "randomness diagrams"-tangible planar visualizations that answer the question: How random is a random vector? The notion of "independence indices" yields a novel measure of correlation for Lévy laws. In general, the concepts and results presented in this paper are applicable to any field of science and engineering with random-vectors empirical data.

Projection correlation between two random vectors.

Science.gov (United States)

Zhu, Liping; Xu, Kai; Li, Runze; Zhong, Wei

2017-12-01

We propose the use of projection correlation to characterize dependence between two random vectors. Projection correlation has several appealing properties. It equals zero if and only if the two random vectors are independent, it is not sensitive to the dimensions of the two random vectors, it is invariant with respect to the group of orthogonal transformations, and its estimation is free of tuning parameters and does not require moment conditions on the random vectors. We show that the sample estimate of the projection correction is [Formula: see text]-consistent if the two random vectors are independent and root-[Formula: see text]-consistent otherwise. Monte Carlo simulation studies indicate that the projection correlation has higher power than the distance correlation and the ranks of distances in tests of independence, especially when the dimensions are relatively large or the moment conditions required by the distance correlation are violated.

Evolutions of the power grid: vector of sustainable development

International Nuclear Information System (INIS)

Croguennoc, Alain; Dalle, Bernard; Archambault, R.; Bony, P.E.; Bouneau, C.; Bourguignon, B.; Bouvier, D.; Beltran, A.; Chauvancy, A.; Chevassus-au-Louis, B.; Citi, S.; Claverie, B.; Colomb, B.; Dallet, M.; Deveaux, L.; Dubus, D.; Fresnedo, S.; Herreros, J.; Herz, O.; Isoard, J.; Jaussaud, E.; Laffaye, H.; Laroche, J.P.; Lasserre, D.; Lebas, N.; Lebranchu, D.; Leclerc, F.; Lemoine, D.; Leydier, C.; Malique, F.; Mazoyer, F.; Meudic, M.A.; Nguefeu, S.; Pajot, S.; Pilate, J.M.; Real, G.; Rosso, F.; Waeraas de Saint Martin, G.; Schwartzmann, S.; Serres, E.

2011-01-01

The abatement of energy consumption and the mass production of renewable energy are the main actions implemented to meet the climate challenge. In this context, the share of electric power in the final consumption is continuously growing up. Adapting the power transportation grid is necessary if we want to take up the challenge of the new paradigm 'new power generation sites, fatal and intermittent energy'. If this grid is the symbol of a modern and well-equipped France, it is also the revealer of our society antagonisms: change without disruption, progress without sacrifice of heritage and natural landscapes. Industries and grid operators will have to show some innovation and anticipation if they want this deep change to be a success. The French power grid has permitted the regional development in the past and will allow to take up the climate challenge in the future. Its inevitable position in the success of past transformations makes it an essential vector of sustainable development. (J.S.)

Mathematical model for optimization of multilayer submerged-arc welding of frame equipment of power units

International Nuclear Information System (INIS)

Pankov, V.V.; Chernyshev, G.G.; Kozlov, N.E.

1987-01-01

A mathematical model for optimization of multilayer submerged arc welding of frame equipment of power units is constructed. The variation-energy method permits to construct the universal mathematical model for strengthening formation of a single bead; the method is reasonable for simulation of a multilayer welded joint. Minimization of the distance between maximum and minimum layer height of a built-up metal is the necessary condition for qualitative formation of the multilayer joint. One can calculate in real time scale the optimal vector of maximally ten parameters under the multilayer welding condition immediately after change in the grooving width using the developed mathematical model of optimization

Simplified Representation of Vector Fields

NARCIS (Netherlands)

Telea, Alexandru; Wijk, Jarke J. van

1999-01-01

Vector field visualization remains a difficult task. Although many local and global visualization methods for vector fields such as flow data exist, they usually require extensive user experience on setting the visualization parameters in order to produce images communicating the desired insight. We

Problems of vector Lagrangians in field theories

International Nuclear Information System (INIS)

Krivsky, I.Yu.; Simulik, V.M.

1997-01-01

A vector Lagrange approach to the Dirac spinor field and the relationship between the vector Lagrangians for the spinor and electromagnetic fields are considered. A vector Lagrange approach for the system of interacting electromagnetic B=(B μ υ)=(E-bar,H-bar) and spinor Ψ fields is constructed. New Lagrangians (scalar and vector) for electromagnetic field in terms of field strengths are found. The foundations of two new QED models are formulated

Used energy-related laboratory equipment grant program for institutions of higher learning. Eligible equipment catalog

Energy Technology Data Exchange (ETDEWEB)

1994-07-01

This is a listing of energy related equipment available through the Energy-Related Laboratory Equipment Grant Program which grants used equipment to institutions of higher education for energy-related research. Information included is an overview of the program, how to apply for a grant of equipment, eligibility requirements, types of equipment available, and the costs for the institution.

Equipment repair in coal mines

Energy Technology Data Exchange (ETDEWEB)

Zhang, S

1982-01-01

Most equipment in Chinese coal mines consists of machinery and equipment produced in the 1950s; the efficiency of 4-62, CTD-57 and 70B/sub 2/ ventilators is 15% lower than that of new ones; that of SSM and AYaP pumps, 10% lower than of modern ones. Equipment renovation is done in three ways: replacing obsolete equipment with new equipment of the same type; improving the performance of existing equipment by introducing efficiency and reconstruction; and replacing obsolete equipment with advanced equipment. It is indicated that the second way, for example, replacement of 4-62 ventilator blades with a maximum efficiency of 73% by 4-72 ventilator blades raises its efficiency to 90%. Replacing the 8DA-8x3 water pump, having a maximum efficiency of 63%, with the 200D 43x3 pump with a maximum efficiency of 78%, enables an electricity savings of 7000 yuan per year, which exceeds all replacement costs (600 yuan). The need to improve equipment maintenance and preventive work to increase equipment service life and to introduce new techniques and efficiency is noted.

BP volume reduction equipment

International Nuclear Information System (INIS)

Kitamura, Yoshinori; Muroo, Yoji; Hamanaka, Isao

2003-01-01

A new type of burnable poison (BP) volume reduction system is currently being developed. Many BP rods, a subcomponent of spent fuel assemblies are discharged from nuclear power reactors. This new system reduces the overall volume of BP rods. The main system consists of BP rod cutting equipment, equipment for the recovery of BP cut pieces, and special transport equipment for the cut rods. The equipment is all operated by hydraulic press cylinders in water to reduce operator exposure to radioactivity. (author)

Exercise Equipment: Neutral Buoyancy

Science.gov (United States)

Shackelford, Linda; Valle, Paul

2016-01-01

Load Bearing Equipment for Neutral Buoyancy (LBE-NB) is an exercise frame that holds two exercising subjects in position as they apply counter forces to each other for lower extremity and spine loading resistance exercises. Resistance exercise prevents bone loss on ISS, but the ISS equipment is too massive for use in exploration craft. Integrating the human into the load directing, load generating, and motion control functions of the exercise equipment generates safe exercise loads with less equipment mass and volume.

22 CFR 135.32 - Equipment.

Science.gov (United States)

2010-04-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

21 CFR 1403.32 - Equipment.

Science.gov (United States)

2010-04-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

45 CFR 602.32 - Equipment.

Science.gov (United States)

2010-10-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

49 CFR 18.32 - Equipment.

Science.gov (United States)

2010-10-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

34 CFR 80.32 - Equipment.

Science.gov (United States)

2010-07-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

10 CFR 600.232 - Equipment.

Science.gov (United States)

2010-01-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

45 CFR 1183.32 - Equipment.

Science.gov (United States)

2010-10-01

... specifically permitted or contemplated by Federal statute. (4) When acquiring replacement equipment, the...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... return. (e) Disposition. When original or replacement equipment acquired under a grant or subgrant is no...

A flight investigation of oscillating air forces: Equipment and technique

Science.gov (United States)

Reed, W. H., III

1975-01-01

The equipment and techniques are described which are to be used in a project aimed at measuring oscillating air forces and dynamic aeroelastic response of a swept wing airplane at high subsonic speeds. Electro-hydraulic inertia type shakers installed in the wing tips will excite various elastic airplane modes while the related oscillating chordwise pressures at two spanwise wing stations and the wing mode shapes are recorded on magnetic tape. The data reduction technique, following the principle of a wattmeter harmonic analyzer employed by Bratt, Wight, and Tilly, utilizes magnetic tape and high speed electronic multipliers to record directly the real and imaginary components of oscillatory data signals relative to a simple harmonic reference signal. Through an extension of this technique an automatic flight-flutter-test data analyzer is suggested in which vector plots of mechanical admittance or impedance would be plotted during the flight test.

On the Development of Creativity and Cooperation Skills in Indigenous Elementary School Students During a LEGO Mindstorms NXT Course

Directory of Open Access Journals (Sweden)

Jenyi Chao

2013-06-01

Full Text Available The objective of the nine-year integrated curriculum in Taiwan is to cultivate the ten basic competencies of students. Nations around the world have also accentuated the importance of key competencies in citizens, and it is hoped that through education, civic literacy can be enhanced. Among the basic competencies, many nations value the abilities to use technology, to be creative, and cooperative. This study investigated the development of two abilities, creativity and cooperation, in indigenous students while they learned basic mechanical concepts in a LEGO Mindstorms NXT course, which comprised nine units, during the 2010-2011 school year. Indigenous Atayal culture and teaching strategies involving collaborative problem solving were integrated into the course. The participants were 24 third graders from an elementary school serving the Atayal Tribes of Nan-ao, Ilan County. Data was collected through pretests, posttests, and classroom observations. The findings of this study are as follows. (1 The scores of the pretests and posttests indicate that the basic mechanical concepts of the students improved significantly. (2 The results of the figural Torrance Tests of Creative Thinking showed that the students improved significantly in fluency, originality, elaboration, openness, and creative potential. (3 In learning, cooperating, and the division of labor, the students were able to perform their respective duties; in discussion, problem-solving, and presentation, they required some guidance from the teacher; in reflection, assessment, and summary, the students displayed high levels of interest and creative performance.

Effective SIMD Vectorization for Intel Xeon Phi Coprocessors

OpenAIRE

Tian, Xinmin; Saito, Hideki; Preis, Serguei V.; Garcia, Eric N.; Kozhukhov, Sergey S.; Masten, Matt; Cherkasov, Aleksei G.; Panchenko, Nikolay

2015-01-01

Efficiently exploiting SIMD vector units is one of the most important aspects in achieving high performance of the application code running on Intel Xeon Phi coprocessors. In this paper, we present several effective SIMD vectorization techniques such as less-than-full-vector loop vectorization, Intel MIC specific alignment optimization, and small matrix transpose/multiplication 2D vectorization implemented in the Intel C/C++ and Fortran production compilers for Intel Xeon Phi coprocessors. A ...

Vectors of rickettsiae in Africa.

Science.gov (United States)

Bitam, Idir

2012-12-01

Vector-borne diseases are caused by parasites, bacteria, or viruses transmitted by the bites of hematophagous arthropods. In Africa, there has been a recent emergence of new diseases and the re-emergence of existing diseases, usually with changes in disease epidemiology (e.g., geographical distribution, prevalence, and pathogenicity). In Africa, rickettsioses are recognized as important emerging vector-borne infections in humans. Rickettsial diseases are transmitted by different types of arthropods, ticks, fleas, lice, and mites. This review will examine the roles of these different arthropod vectors and their geographical distributions. Copyright © 2012 Elsevier GmbH. All rights reserved.

Development of manufacturing equipment and QC equipment for DUPIC fuel

International Nuclear Information System (INIS)

Yang, Myung Seung; Park, J.J.; Lee, J.W.; Kim, S.S.; Yim, S.P.; Kim, J.H.; Kim, K.H.; Na, S.H.; Kim, W.K.; Shin, J.M.; Lee, D.Y.; Cho, K.H.; Lee, Y.S.; Sohn, J.S.; Kim, M.J.

1999-05-01

In this study, DUPIC powder and pellet fabrication equipment, welding system, QC equipment, and fission gas treatment are developed to fabricate DUPIC fuel at IMEF M6 hot cell. The systems are improved to be suitable for remote operation and maintenance with the manipulator at hot cell. Powder and pellet fabrication equipment have been recently developed. The systems are under performance test to check remote operation and maintenance. Welding chamber and jigs are designed and developed to remotely weld DUPIC fuel rod with manipulators at hot cell. Remote quality control equipment are being tested for analysis and inspection of DUPIC fuel characteristics at hot cell. And trapping characteristics is analyzed for cesium and ruthenium released under oxidation/reduction and sintering processes. The design criteria and process flow diagram of fission gas treatment system are prepared incorporating the experimental results. The fission gas treatment system has been successfully manufactured. (Author). 33 refs., 14 tabs., 91 figs

Modeling vector nonlinear time series using POLYMARS

NARCIS (Netherlands)

de Gooijer, J.G.; Ray, B.K.

2003-01-01

A modified multivariate adaptive regression splines method for modeling vector nonlinear time series is investigated. The method results in models that can capture certain types of vector self-exciting threshold autoregressive behavior, as well as provide good predictions for more general vector

Y-method for subsea equipment installation; Metodo Y de instalacao de equipamentos 'subsea'

Energy Technology Data Exchange (ETDEWEB)

Santos, Melquisedec F.; Neves, Cassiano R. [SUBSIN - Subsea Integrity Engenharia e Projetos Ltda., Rio de Janeiro, RJ (Brazil)

2008-07-01

The paper presents a new design of equipment to fall to the seabed, and the results of preliminary calculations to validate the concept. The goals to be achieved consider the current reality of offshore production demands the increasing use of equipment background with large mass and dimensions at increasing depths. The increase of the depths brings necessarily, independent of the mass value, the appearance of a 'zone of resonance' in which pick of tensions arise in values often exceed the capacity of the traction cables designed with all the factors of safety required in standard. This phenomenon necessitates the use of equipment that create the 'spring effect', damping equipment installed in the line of tension involving the use of cranes and ferries or compensating for 'heave' trying to minimize the effects of the balance of the sea in the operation involving where the use of vessels of large size and high cost. By splitting the vector of the load in two, by two different boats, six variables are introduced make it easy to control. The variables are: relative positions and lengths of the cable of witch vessel and the speed of descent of these cables. This development emphasized the cost factor to meet technical and operational characteristics of this type of work, including the same way all the safety requirements and operational speed. As a result of the additional method, we were able to introduce a new parameter in the coupling of equipment in the background since the method also brings the possibility of total control of the speed of approach and touch a tool in its 'slot' even it in a sea adverse. (author)

Support vector machines applications

CERN Document Server

Guo, Guodong

2014-01-01

Support vector machines (SVM) have both a solid mathematical background and good performance in practical applications. This book focuses on the recent advances and applications of the SVM in different areas, such as image processing, medical practice, computer vision, pattern recognition, machine learning, applied statistics, business intelligence, and artificial intelligence. The aim of this book is to create a comprehensive source on support vector machine applications, especially some recent advances.

Effective SIMD Vectorization for Intel Xeon Phi Coprocessors

Directory of Open Access Journals (Sweden)

Xinmin Tian

2015-01-01

Full Text Available Efficiently exploiting SIMD vector units is one of the most important aspects in achieving high performance of the application code running on Intel Xeon Phi coprocessors. In this paper, we present several effective SIMD vectorization techniques such as less-than-full-vector loop vectorization, Intel MIC specific alignment optimization, and small matrix transpose/multiplication 2D vectorization implemented in the Intel C/C++ and Fortran production compilers for Intel Xeon Phi coprocessors. A set of workloads from several application domains is employed to conduct the performance study of our SIMD vectorization techniques. The performance results show that we achieved up to 12.5x performance gain on the Intel Xeon Phi coprocessor. We also demonstrate a 2000x performance speedup from the seamless integration of SIMD vectorization and parallelization.

Engineering BioBrick vectors from BioBrick parts

Directory of Open Access Journals (Sweden)

Knight Thomas F

2008-04-01

Full Text Available Abstract Background The underlying goal of synthetic biology is to make the process of engineering biological systems easier. Recent work has focused on defining and developing standard biological parts. The technical standard that has gained the most traction in the synthetic biology community is the BioBrick standard for physical composition of genetic parts. Parts that conform to the BioBrick assembly standard are BioBrick standard biological parts. To date, over 2,000 BioBrick parts have been contributed to, and are available from, the Registry of Standard Biological Parts. Results Here we extended the same advantages of BioBrick standard biological parts to the plasmid-based vectors that are used to provide and propagate BioBrick parts. We developed a process for engineering BioBrick vectors from BioBrick parts. We designed a new set of BioBrick parts that encode many useful vector functions. We combined the new parts to make a BioBrick base vector that facilitates BioBrick vector construction. We demonstrated the utility of the process by constructing seven new BioBrick vectors. We also successfully used the resulting vectors to assemble and propagate other BioBrick standard biological parts. Conclusion We extended the principles of part reuse and standardization to BioBrick vectors. As a result, myriad new BioBrick vectors can be readily produced from all existing and newly designed BioBrick parts. We invite the synthetic biology community to (1 use the process to make and share new BioBrick vectors; (2 expand the current collection of BioBrick vector parts; and (3 characterize and improve the available collection of BioBrick vector parts.

Bioreactor production of recombinant herpes simplex virus vectors.

Science.gov (United States)

Knop, David R; Harrell, Heather

2007-01-01

Serotypical application of herpes simplex virus (HSV) vectors to gene therapy (type 1) and prophylactic vaccines (types 1 and 2) has garnered substantial clinical interest recently. HSV vectors and amplicons have also been employed as helper virus constructs for manufacture of the dependovirus adeno-associated virus (AAV). Large quantities of infectious HSV stocks are requisite for these therapeutic applications, requiring a scalable vector manufacturing and processing platform comprised of unit operations which accommodate the fragility of HSV. In this study, production of a replication deficient rHSV-1 vector bearing the rep and cap genes of AAV-2 (denoted rHSV-rep2/cap2) was investigated. Adaptation of rHSV production from T225 flasks to a packed bed, fed-batch bioreactor permitted an 1100-fold increment in total vector production without a decrease in specific vector yield (pfu/cell). The fed-batch bioreactor system afforded a rHSV-rep2/cap2 vector recovery of 2.8 x 10(12) pfu. The recovered vector was concentrated by tangential flow filtration (TFF), permitting vector stocks to be formulated at greater than 1.5 x 10(9) pfu/mL.

Cosmological evolution in vector-tensor theories of gravity

International Nuclear Information System (INIS)

Beltran Jimenez, Jose; Maroto, Antonio L.

2009-01-01

We present a detailed study of the cosmological evolution in general vector-tensor theories of gravity without potential terms. We consider the evolution of the vector field throughout the expansion history of the Universe and carry out a classification of models according to the behavior of the vector field in each cosmological epoch. We also analyze the case in which the Universe is dominated by the vector field, performing a complete analysis of the system phase map and identifying those attracting solutions which give rise to accelerated expansion. Moreover, we consider the evolution in a universe filled with a pressureless fluid in addition to the vector field and study the existence of attractors in which we can have a transition from matter domination to vector domination with accelerated expansion so that the vector field may play the role of dark energy. We find that the existence of solutions with late-time accelerated expansion is a generic prediction of vector-tensor theories and that such solutions typically lead to the presence of future singularities. Finally, limits from local gravity tests are used to get constraints on the value of the vector field at small (Solar System) scales.

n-Characteristic Vector Fields of Contact Manifoldss

OpenAIRE

Hassanzadeh, Babak

2017-01-01

In present paper we define and study $n$-characteristic vector fields. We present definition of Tanaka-Webster connection, then use it for studying the behavior of $n$-characteristic vector fields. Also we show some results about of these vector fields by Tanaka-Webster connection.

Successful vectorization - reactor physics Monte Carlo code

International Nuclear Information System (INIS)

Martin, W.R.

1989-01-01

Most particle transport Monte Carlo codes in use today are based on the ''history-based'' algorithm, wherein one particle history at a time is simulated. Unfortunately, the ''history-based'' approach (present in all Monte Carlo codes until recent years) is inherently scalar and cannot be vectorized. In particular, the history-based algorithm cannot take advantage of vector architectures, which characterize the largest and fastest computers at the current time, vector supercomputers such as the Cray X/MP or IBM 3090/600. However, substantial progress has been made in recent years in developing and implementing a vectorized Monte Carlo algorithm. This algorithm follows portions of many particle histories at the same time and forms the basis for all successful vectorized Monte Carlo codes that are in use today. This paper describes the basic vectorized algorithm along with descriptions of several variations that have been developed by different researchers for specific applications. These applications have been mainly in the areas of neutron transport in nuclear reactor and shielding analysis and photon transport in fusion plasmas. The relative merits of the various approach schemes will be discussed and the present status of known vectorization efforts will be summarized along with available timing results, including results from the successful vectorization of 3-D general geometry, continuous energy Monte Carlo. (orig.)

45 CFR 1174.32 - Equipment.

Science.gov (United States)

2010-10-01

... contemplated by Federal statute. (4) When acquiring replacement equipment, the grantee or subgrantee may use... requirements. Procedures for managing equipment (including replacement equipment), whether acquired in whole or... original or replacement equipment acquired under a grant or subgrant is no longer needed for the original...

45 CFR 1157.32 - Equipment.

Science.gov (United States)

2010-10-01

... contemplated by Federal statute. (4) When acquiring replacement equipment, the grantee or subgrantee may use... requirements. Procedures for managing equipment (including replacement equipment), whether acquired in whole or... original or replacement equipment acquired under a grant or subgrant is no longer needed for the original...

A study of biorthogonal multiple vector-valued wavelets

International Nuclear Information System (INIS)

Han Jincang; Cheng Zhengxing; Chen Qingjiang

2009-01-01

The notion of vector-valued multiresolution analysis is introduced and the concept of biorthogonal multiple vector-valued wavelets which are wavelets for vector fields, is introduced. It is proved that, like in the scalar and multiwavelet case, the existence of a pair of biorthogonal multiple vector-valued scaling functions guarantees the existence of a pair of biorthogonal multiple vector-valued wavelet functions. An algorithm for constructing a class of compactly supported biorthogonal multiple vector-valued wavelets is presented. Their properties are investigated by means of operator theory and algebra theory and time-frequency analysis method. Several biorthogonality formulas regarding these wavelet packets are obtained.

3-D Vector Flow Imaging

DEFF Research Database (Denmark)

Holbek, Simon

, if this significant reduction in the element count can still provide precise and robust 3-D vector flow estimates in a plane. The study concludes that the RC array is capable of estimating precise 3-D vector flow both in a plane and in a volume, despite the low channel count. However, some inherent new challenges...... ultrasonic vector flow estimation and bring it a step closer to a clinical application. A method for high frame rate 3-D vector flow estimation in a plane using the transverse oscillation method combined with a 1024 channel 2-D matrix array is presented. The proposed method is validated both through phantom...... hampers the task of real-time processing. In a second study, some of the issue with the 2-D matrix array are solved by introducing a 2-D row-column (RC) addressing array with only 62 + 62 elements. It is investigated both through simulations and via experimental setups in various flow conditions...

Black holes in vector-tensor theories

Energy Technology Data Exchange (ETDEWEB)

Heisenberg, Lavinia [Institute for Theoretical Studies, ETH Zurich, Clausiusstrasse 47, 8092 Zurich (Switzerland); Kase, Ryotaro; Tsujikawa, Shinji [Department of Physics, Faculty of Science, Tokyo University of Science, 1-3, Kagurazaka, Shinjuku-ku, Tokyo 162-8601 (Japan); Minamitsuji, Masato, E-mail: lavinia.heisenberg@eth-its.ethz.ch, E-mail: r.kase@rs.tus.ac.jp, E-mail: masato.minamitsuji@tecnico.ulisboa.pt, E-mail: shinji@rs.kagu.tus.ac.jp [Centro Multidisciplinar de Astrofisica—CENTRA, Departamento de Fisica, Instituto Superior Tecnico—IST, Universidade de Lisboa—UL, Avenida Rovisco Pais 1, 1049-001 Lisboa (Portugal)

2017-08-01

We study static and spherically symmetric black hole (BH) solutions in second-order generalized Proca theories with nonminimal vector field derivative couplings to the Ricci scalar, the Einstein tensor, and the double dual Riemann tensor. We find concrete Lagrangians which give rise to exact BH solutions by imposing two conditions of the two identical metric components and the constant norm of the vector field. These exact solutions are described by either Reissner-Nordström (RN), stealth Schwarzschild, or extremal RN solutions with a non-trivial longitudinal mode of the vector field. We then numerically construct BH solutions without imposing these conditions. For cubic and quartic Lagrangians with power-law couplings which encompass vector Galileons as the specific cases, we show the existence of BH solutions with the difference between two non-trivial metric components. The quintic-order power-law couplings do not give rise to non-trivial BH solutions regular throughout the horizon exterior. The sixth-order and intrinsic vector-mode couplings can lead to BH solutions with a secondary hair. For all the solutions, the vector field is regular at least at the future or past horizon. The deviation from General Relativity induced by the Proca hair can be potentially tested by future measurements of gravitational waves in the nonlinear regime of gravity.

Investigation of Optimal Integrated Circuit Raster Image Vectorization Method

Directory of Open Access Journals (Sweden)

Leonas Jasevičius

2011-03-01

Full Text Available Visual analysis of integrated circuit layer requires raster image vectorization stage to extract layer topology data to CAD tools. In this paper vectorization problems of raster IC layer images are presented. Various line extraction from raster images algorithms and their properties are discussed. Optimal raster image vectorization method was developed which allows utilization of common vectorization algorithms to achieve the best possible extracted vector data match with perfect manual vectorization results. To develop the optimal method, vectorized data quality dependence on initial raster image skeleton filter selection was assessed.Article in Lithuanian

Environmental management: a re-emerging vector control strategy.

Science.gov (United States)

Ault, S K

1994-01-01

Vector control may be accomplished by environmental management (EM), which consists of permanent or long-term modification of the environment, temporary or seasonal manipulation of the environment, and modifying or changing our life styles and practices to reduce human contact with infective vectors. The primary focus of this paper is EM in the control of human malaria, filariasis, arboviruses, Chagas' disease, and schistosomiasis. Modern EM developed as a discipline based primarily in ecologic principles and lessons learned from the adverse environmental impacts of rural development projects. Strategies such as the suppression of vector populations through the provision of safe water supplies, proper sanitation, solid waste management facilities, sewerage and excreta disposal systems, water manipulation in dams and irrigation systems, vector diversion by zooprophylaxis, and vector exclusion by improved housing, are discussed with appropriate examples. Vectors of malaria, filariasis, Chagas' disease, and schistosomiasis have been controlled by drainage or filling aquatic breeding sites, improved housing and sanitation, the use of expanded polystyrene beads, zooprophylaxis, or the provision of household water supplies. Community participation has been effective in the suppression of dengue vectors in Mexico and the Dominican Republic. Alone or combined with other vector control methods, EM has been proven to be a successful approach to vector control in a number of places. The future of EM in vector control looks promising.

PROBLEMS PERTAINING TO DIVERSIFICATION OF CIVIL EQUIPMENT IN EQUIPMENT OF MILITARY PURPOSE

OpenAIRE

A. I. Kotlabay; V. A. Korobkin; V. F. Tamelo; I. V. Kostko; S. V. Kondratiev

2009-01-01

Study of directions concerning development of military equipment, its modernization with the purpose to improve its military efficiency is an actual problem for the Armed Forces, military science, designers and researchers.The paper analyzes and estimates possibilities to use civil equipment for military purpose. Problems pertaining to technologies of double application, diversification of civil equipment in military engineering machinery are considered in the paper.

20 CFR 437.32 - Equipment.

Science.gov (United States)

2010-04-01

... contemplated by Federal statute. (4) When acquiring replacement equipment, the grantee or subgrantee may use.... Procedures for managing equipment (including replacement equipment), whether acquired in whole or in part... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Equipment. 437.32 Section 437.32 Employees...

TimesVector: a vectorized clustering approach to the analysis of time series transcriptome data from multiple phenotypes.

Science.gov (United States)

Jung, Inuk; Jo, Kyuri; Kang, Hyejin; Ahn, Hongryul; Yu, Youngjae; Kim, Sun

2017-12-01

Identifying biologically meaningful gene expression patterns from time series gene expression data is important to understand the underlying biological mechanisms. To identify significantly perturbed gene sets between different phenotypes, analysis of time series transcriptome data requires consideration of time and sample dimensions. Thus, the analysis of such time series data seeks to search gene sets that exhibit similar or different expression patterns between two or more sample conditions, constituting the three-dimensional data, i.e. gene-time-condition. Computational complexity for analyzing such data is very high, compared to the already difficult NP-hard two dimensional biclustering algorithms. Because of this challenge, traditional time series clustering algorithms are designed to capture co-expressed genes with similar expression pattern in two sample conditions. We present a triclustering algorithm, TimesVector, specifically designed for clustering three-dimensional time series data to capture distinctively similar or different gene expression patterns between two or more sample conditions. TimesVector identifies clusters with distinctive expression patterns in three steps: (i) dimension reduction and clustering of time-condition concatenated vectors, (ii) post-processing clusters for detecting similar and distinct expression patterns and (iii) rescuing genes from unclassified clusters. Using four sets of time series gene expression data, generated by both microarray and high throughput sequencing platforms, we demonstrated that TimesVector successfully detected biologically meaningful clusters of high quality. TimesVector improved the clustering quality compared to existing triclustering tools and only TimesVector detected clusters with differential expression patterns across conditions successfully. The TimesVector software is available at http://biohealth.snu.ac.kr/software/TimesVector/. sunkim.bioinfo@snu.ac.kr. Supplementary data are available at

Vector assembly of colloids on monolayer substrates

Science.gov (United States)

Jiang, Lingxiang; Yang, Shenyu; Tsang, Boyce; Tu, Mei; Granick, Steve

2017-06-01

The key to spontaneous and directed assembly is to encode the desired assembly information to building blocks in a programmable and efficient way. In computer graphics, raster graphics encodes images on a single-pixel level, conferring fine details at the expense of large file sizes, whereas vector graphics encrypts shape information into vectors that allow small file sizes and operational transformations. Here, we adapt this raster/vector concept to a 2D colloidal system and realize `vector assembly' by manipulating particles on a colloidal monolayer substrate with optical tweezers. In contrast to raster assembly that assigns optical tweezers to each particle, vector assembly requires a minimal number of optical tweezers that allow operations like chain elongation and shortening. This vector approach enables simple uniform particles to form a vast collection of colloidal arenes and colloidenes, the spontaneous dissociation of which is achieved with precision and stage-by-stage complexity by simply removing the optical tweezers.

Free-world microelectronic manufacturing equipment

Science.gov (United States)

Kilby, J. S.; Arnold, W. H.; Booth, W. T.; Cunningham, J. A.; Hutcheson, J. D.; Owen, R. W.; Runyan, W. R.; McKenney, Barbara L.; McGrain, Moira; Taub, Renee G.

1988-12-01

Equipment is examined and evaluated for the manufacture of microelectronic integrated circuit devices and sources for that equipment within the Free World. Equipment suitable for the following are examined: single-crystal silicon slice manufacturing and processing; required lithographic processes; wafer processing; device packaging; and test of digital integrated circuits. Availability of the equipment is also discussed, now and in the near future. Very adequate equipment for most stages of the integrated circuit manufacturing process is available from several sources, in different countries, although the best and most widely used versions of most manufacturing equipment are made in the United States or Japan. There is also an active market in used equipment, suitable for manufacture of capable integrated circuits with performance somewhat short of the present state of the art.

34 CFR 74.34 - Equipment.

Science.gov (United States)

2010-07-01

... as program income. (e) When acquiring replacement equipment, the recipient may use the equipment to... replacement equipment subject to the approval of the Secretary. (f) The recipient's property management... 34 Education 1 2010-07-01 2010-07-01 false Equipment. 74.34 Section 74.34 Education Office of the...

45 CFR 2541.320 - Equipment.

Science.gov (United States)

2010-10-01

... replacement equipment, the grantee or subgrantee may use the equipment to be replaced as a trade-in or sell... replacement equipment), whether acquired in whole or in part with grant funds, until disposition takes place... ensure the highest possible return. (e) Disposition. When original or replacement equipment acquired...

Visual communication and terminal equipment

International Nuclear Information System (INIS)

Kang, Cheol Hui

1988-06-01

This book is divided two parts about visual communication and terminal equipment. The first part introduces visual communication, which deals with foundation of visual communication, technique of visual communication, equipment of visual communication, a facsimile and pictorial image system. The second part contains terminal equipment such as telephone, terminal equipment for data transmission on constitution and constituent of terminal equipment for data transmission, input device and output device, terminal device and up-to-date terminal device.

Visual communication and terminal equipment

Energy Technology Data Exchange (ETDEWEB)

Kang, Cheol Hui

1988-06-15

This book is divided two parts about visual communication and terminal equipment. The first part introduces visual communication, which deals with foundation of visual communication, technique of visual communication, equipment of visual communication, a facsimile and pictorial image system. The second part contains terminal equipment such as telephone, terminal equipment for data transmission on constitution and constituent of terminal equipment for data transmission, input device and output device, terminal device and up-to-date terminal device.

Herbivore arthropods benefit from vectoring plant viruses

NARCIS (Netherlands)

Belliure, B.; Janssen, A.; Maris, P.C.; Peters, D.; Sabelis, M.W.

2005-01-01

Plants infected with pathogens often attract the pathogens' vectors, but it is not clear if this is advantageous to the vectors. We therefore quantified the direct and indirect (through the host plant) effects of a pathogen on its vector. A positive direct effect of the plant-pathogenic Tomato

Equipment design guidance document for flammable gas waste storage tank new equipment

International Nuclear Information System (INIS)

Smet, D.B.

1996-01-01

This document is intended to be used as guidance for design engineers who are involved in design of new equipment slated for use in Flammable Gas Waste Storage Tanks. The purpose of this document is to provide design guidance for all new equipment intended for application into those Hanford storage tanks in which flammable gas controls are required to be addressed as part of the equipment design. These design criteria are to be used as guidance. The design of each specific piece of new equipment shall be required, as a minimum to be reviewed by qualified Unreviewed Safety Question evaluators as an integral part of the final design approval. Further Safety Assessment may be also needed. This guidance is intended to be used in conjunction with the Operating Specifications Documents (OSDs) established for defining work controls in the waste storage tanks. The criteria set forth should be reviewed for applicability if the equipment will be required to operate in locations containing unacceptable concentrations of flammable gas

Genetic modification of hematopoietic cells using retroviral and lentiviral vectors: safety considerations for vector design and delivery into target cells.

Science.gov (United States)

Dropulic, Boro

2005-07-01

The recent development of leukemia in three patients following retroviral vector gene transfer in hematopoietic stem cells, resulting in the death of one patient, has raised safety concerns for the use of integrating gene transfer vectors for human gene therapy. This review discusses these serious adverse events from the perspective of whether restrictions on vector design and vector-modified target cells are warranted at this time. A case is made against presently establishing specific restrictions for vector design and transduced cells; rather, their safety should be ascertained by empiric evaluation in appropriate preclinical models on a case-by-case basis. Such preclinical data, coupled with proper informed patient consent and a risk-benefit ratio analysis, provide the best available prospective evaluation of gene transfer vectors prior to their translation into the clinic.

Environmental/dynamic mechanical equipment qualification and dynamic electrical equipment qualification program (EDQP)

International Nuclear Information System (INIS)

Hunter, J.A.

1984-01-01

Equipment qualification research is being conducted to investigate acceptable criteria, requirements, and methodologies for the dynamic (including seismic) and environmental qualification of mechanical equipment and for the dynamic (including seismic) qualification of electrical equipment. The program is organized into three elements: (1) General Research, (2) Environmental Research, and (3) Dynamic Research. This paper presents the highlights of the results to date in these three elements of the program

Meromorphic Vector Fields and Circle Packings

DEFF Research Database (Denmark)

Dias, Kealey

The objective of the Ph.D. project is to initiate a classification of bifurcations of meromorphic vector fields and to clarify their relation to circle packings. Technological applications are to image analysis and to effective grid generation using discrete conformal mappings. The two branches...... of dynamical systems, continuous and discrete, correspond to the study of differential equations (vector fields) and iteration of mappings respectively. In holomorphic dynamics, the systems studied are restricted to those described by holomorphic (complex analytic) functions or meromorphic (allowing poles...... as singularities) functions. There already exists a well-developed theory for iterative holomorphic dynamical systems, and successful relations found between iteration theory and flows of vector fields have been one of the main motivations for the recent interest in holomorphic vector fields. Restricting...

Use of Equipment Information System (EQUIS) to determine priority for purchasing safeguards equipment

International Nuclear Information System (INIS)

Silberberg, S.

1988-01-01

To manage its large world-wide inventory of safeguards equipment, the IAEA Safeguards department uses a computerized Equipment Information System (EQUIS). EQUIS data have been analyzed using Queueing Theory to determine if inventory is adequate to meet inspector demands and in those cases where it is inadequate, to indicate how many additional units should be procured. Results are tabulated for various types of non-destructive analysis (NDA) equipment. For equipment where there is a high turnover and hence a large amount of data, the analysis provides a powerful tool for assisting procurement decisions

Characterizing Convexity of Games using Marginal Vectors

NARCIS (Netherlands)

van Velzen, S.; Hamers, H.J.M.; Norde, H.W.

2003-01-01

In this paper we study the relation between convexity of TU games and marginal vectors.We show that if specfic marginal vectors are core elements, then the game is convex.We characterize sets of marginal vectors satisfying this property, and we derive the formula for the minimum number of marginal

How effective is integrated vector management against malaria and lymphatic filariasis where the diseases are transmitted by the same vector?

OpenAIRE

Stone, C.; Lindsay, S.W.; Chitnis, N.

2014-01-01

Background: The opportunity to integrate vector management across multiple vector-borne diseases is particularly plausible for malaria and lymphatic filariasis (LF) control where both diseases are transmitted by the same vector. To date most examples of integrated control targeting these diseases have been unanticipated consequences of malaria vector control, rather than planned strategies that aim to maximize the efficacy and take the complex ecological and biological interactions between th...

Overall Equipment Effectiveness Implementation Criteria

Science.gov (United States)

Abramova, I. G.; Abramov, D. A.

2018-01-01

This article documents the methods applied in production control technics specifically focused on commonly used parameter OEE (Overall Equipment Effectiveness). The indicators of extensive and intensive use of equipment are considered. Their appointment this is comparison in the same type of production within the industry and comparison of single-type and / or different types of equipment in terms of capacity. However, it is shown that there is no possibility of revealing the reasons for the machine’s operation: productive / unproductive, with disturbances. Therefore, in the article reveals the approaches to calculating the indicator characterizing the direct operation of the equipment. The Machine Load coefficient is approaching closely to the indicator of the efficiency of the use of equipment. Methods analysis is proceeded through the historically applied techniques such as “Stopwatch” and “Motion” studies. Was performed the analysis of the efficiency index of OEE equipment using the comparable indexes performance of equipment in the Russian practice. An important indicator of OEE contains three components. The meaning of each of them reflects historically applicable indicators. The value of the availability of equipment indicator is close to the value of the equipment extensibility index. The value of the indicator of the efficiency of work can be compared with the characteristic of the capacity of the equipment and the indicator of the quality level can meet the requirements for compliance with the manufacturing technology. Shown that the sum of the values of the coefficient of “Availability” of the equipment and the value of the “Factor of compaction of working hours” are one. As well as the total value of the indicator “level of quality” and the coefficient of marriage given in the result unit. The measurability of the indicators makes it possible to make a prediction about efficiency of the equipment.

Two-dimensional gauge model with vector U(1) and axial-vector U(1) symmetries

International Nuclear Information System (INIS)

Watabiki, Y.

1989-01-01

We have succeeded in constructing a two-dimensional gauge model with both vector U(1) and axial-vector U(1) symmetries. This model is exactly solvable. The Schwinger term vanishes in this model as a consequence of the above symmetries, and negative-norm states appear. However, the norms of physical states are always positive semidefinite due to the gauge symmetries

Air travel and vector-borne disease movement.

Science.gov (United States)

Tatem, A J; Huang, Z; Das, A; Qi, Q; Roth, J; Qiu, Y

2012-12-01

Recent decades have seen substantial expansions in the global air travel network and rapid increases in traffic volumes. The effects of this are well studied in terms of the spread of directly transmitted infections, but the role of air travel in the movement of vector-borne diseases is less well understood. Increasingly however, wider reaching surveillance for vector-borne diseases and our improving abilities to map the distributions of vectors and the diseases they carry, are providing opportunities to better our understanding of the impact of increasing air travel. Here we examine global trends in the continued expansion of air transport and its impact upon epidemiology. Novel malaria and chikungunya examples are presented, detailing how geospatial data in combination with information on air traffic can be used to predict the risks of vector-borne disease importation and establishment. Finally, we describe the development of an online tool, the Vector-Borne Disease Airline Importation Risk (VBD-Air) tool, which brings together spatial data on air traffic and vector-borne disease distributions to quantify the seasonally changing risks for importation to non-endemic regions. Such a framework provides the first steps towards an ultimate goal of adaptive management based on near real time flight data and vector-borne disease surveillance.

Bunyavirus-Vector Interactions

Directory of Open Access Journals (Sweden)

Kate McElroy Horne

2014-11-01

Full Text Available The Bunyaviridae family is comprised of more than 350 viruses, of which many within the Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus genera are significant human or agricultural pathogens. The viruses within the Orthobunyavirus, Nairovirus, and Phlebovirus genera are transmitted by hematophagous arthropods, such as mosquitoes, midges, flies, and ticks, and their associated arthropods not only serve as vectors but also as virus reservoirs in many cases. This review presents an overview of several important emerging or re-emerging bunyaviruses and describes what is known about bunyavirus-vector interactions based on epidemiological, ultrastructural, and genetic studies of members of this virus family.

Fault Diagnosis of Plunger Pump in Truck Crane Based on Relevance Vector Machine with Particle Swarm Optimization Algorithm

Directory of Open Access Journals (Sweden)

Wenliao Du

2013-01-01

Full Text Available Promptly and accurately dealing with the equipment breakdown is very important in terms of enhancing reliability and decreasing downtime. A novel fault diagnosis method PSO-RVM based on relevance vector machines (RVM with particle swarm optimization (PSO algorithm for plunger pump in truck crane is proposed. The particle swarm optimization algorithm is utilized to determine the kernel width parameter of the kernel function in RVM, and the five two-class RVMs with binary tree architecture are trained to recognize the condition of mechanism. The proposed method is employed in the diagnosis of plunger pump in truck crane. The six states, including normal state, bearing inner race fault, bearing roller fault, plunger wear fault, thrust plate wear fault, and swash plate wear fault, are used to test the classification performance of the proposed PSO-RVM model, which compared with the classical models, such as back-propagation artificial neural network (BP-ANN, ant colony optimization artificial neural network (ANT-ANN, RVM, and support vectors, machines with particle swarm optimization (PSO-SVM, respectively. The experimental results show that the PSO-RVM is superior to the first three classical models, and has a comparative performance to the PSO-SVM, the corresponding diagnostic accuracy achieving as high as 99.17% and 99.58%, respectively. But the number of relevance vectors is far fewer than that of support vector, and the former is about 1/12–1/3 of the latter, which indicates that the proposed PSO-RVM model is more suitable for applications that require low complexity and real-time monitoring.

Lyapunov, singular and bred vectors in a multi-scale system: an empirical exploration of vectors related to instabilities

International Nuclear Information System (INIS)

Norwood, Adrienne; Kalnay, Eugenia; Ide, Kayo; Yang, Shu-Chih; Wolfe, Christopher

2013-01-01

We compute and compare the three types of vectors frequently used to explore the instability properties of dynamical models, namely Lyapunov vectors (LVs), singular vectors (SVs) and bred vectors (BVs) in two systems, using the Wolfe–Samelson (2007 Tellus A 59 355–66) algorithm to compute all of the Lyapunov vectors. The first system is the Lorenz (1963 J. Atmos. Sci. 20 130–41) three-variable model. Although the leading Lyapunov vector, LV1, grows fastest globally, the second Lyapunov vector, LV2, which has zero growth globally, often grows faster than LV1 locally. Whenever this happens, BVs grow closer to LV2, suggesting that in larger atmospheric or oceanic models where several instabilities can grow in different areas of the world, BVs will grow toward the fastest growing local unstable mode. A comparison of their growth rates at different times shows that all three types of dynamical vectors have the ability to predict regime changes and the duration of the new regime based on their growth rates in the last orbit of the old regime, as shown for BVs by Evans et al (2004 Bull. Am. Meteorol. Soc. 520–4). LV1 and BVs have similar predictive skill, LV2 has a tendency to produce false alarms, and even LV3 shows that maximum decay is also associated with regime change. Initial and final SVs grow much faster and are the most accurate predictors of regime change, although the characteristics of the initial SVs are strongly dependent on the length of the optimization window. The second system is the toy ‘ocean-atmosphere’ model developed by Peña and Kalnay (2004 Nonlinear Process. Geophys. 11 319–27) coupling three Lorenz (1963 J. Atmos. Sci. 20 130–41) systems with different time scales, in order to test the effects of fast and slow modes of growth on the dynamical vectors. A fast ‘extratropical atmosphere’ is weakly coupled to a fast ‘tropical atmosphere’ which is, in turn, strongly coupled to a slow ‘ocean’ system, the latter coupling

Generalized 2-vector spaces and general linear 2-groups

OpenAIRE

Elgueta, Josep

2008-01-01

In this paper a notion of {\\it generalized 2-vector space} is introduced which includes Kapranov and Voevodsky 2-vector spaces. Various kinds of generalized 2-vector spaces are considered and examples are given. The existence of non free generalized 2-vector spaces and of generalized 2-vector spaces which are non Karoubian (hence, non abelian) categories is discussed, and it is shown how any generalized 2-vector space can be identified with a full subcategory of an (abelian) functor category ...

The charge form factor of the neutron from sup 2 H-vector, (e-vector, e' n)p

CERN Document Server

Passchier, I; Szczerba, D; Alarcon, R; Bauer, T S; Boersma, D J; Van der Brand, J F J; Bulten, H J; Ferro-Luzzi, M; Higinbotham, D W; Jager, C W D; Klous, S; Kolster, H; Lang, J; Nikolenko, D M; Nooren, G J; Norum, B E; Poolman, H R; Rachek, Igor A; Simani, M C; Six, E; Vries, H D; Wang, K; Zhou, Z L

2000-01-01

We report on the first measurement of spin-correlation parameters in quasifree electron scattering from vector-polarized deuterium. Polarized electrons were injected into an electron storage ring at a beam energy of 720 MeV. A Siberian snake was employed to preserve longitudinal polarization at the interaction point. Vector-polarized deuterium was produced by an atomic beam source and injected into an open-ended cylindrical cell, internal to the electron storage ring. The spin correlation parameter A sup V sub e sub d was measured for the reaction sup 2 H-vector, (e-vector, e'n)p at a four-momentum transfer squared of 0.21 (GeV/c) sup 2 from which a value for the charge form factor of the neutron was extracted.

Chapter 12. Space Heating Equipment

Energy Technology Data Exchange (ETDEWEB)

Rafferty, Kevin D.

1998-01-01

The performance evaluation of space heating equipment for a geothermal application is generally considered from either of two perspectives: (a) selecting equipment for installation in new construction, or (b) evaluating the performance and retrofit requirements of an existing system. With regard to new construction, the procedure is relatively straightforward. Once the heating requirements are determined, the process need only involve the selection of appropriately sized hot water heating equipment based on the available water temperature. It is important to remember that space heating equipment for geothermal applications is the same equipment used in non-geothermal applications. What makes geothermal applications unique is that the equipment is generally applied at temperatures and flow rates that depart significantly from traditional heating system design. This chapter presents general considerations for the performance of heating equipment at non-standard temperature and flow conditions, retrofit of existing systems, and aspects of domestic hot water heating.

Construction of expression vectors carrying mouse peroxisomal ...

African Journals Online (AJOL)

The aim of this study was to construct expression vectors carrying mouse peroxisomal protein gene (PEP-cDNA) in prokaryotic and mammalian expression vectors in ... pGEX6p2-PEP and pUcD3-FLAG-PEP constructed vectors were transformed into the one shot TOP10 and JM105 bacterial competent cells, respectively.

Vector Fields and Flows on Differentiable Stacks

DEFF Research Database (Denmark)

A. Hepworth, Richard

2009-01-01

This paper introduces the notions of vector field and flow on a general differentiable stack. Our main theorem states that the flow of a vector field on a compact proper differentiable stack exists and is unique up to a uniquely determined 2-cell. This extends the usual result on the existence...... of vector fields....

Extremal vectors and rectifiability | Enflo | Quaestiones Mathematicae

African Journals Online (AJOL)

Extremal vectors and rectifiability. ... The concept of extremal vectors of a linear operator with a dense range but not onto on a Hilbert space was introduced by P. Enflo in 1996 as a new approach to study invariant subspaces ... We show that in general curves that map numbers to backward minimal vectors are not rectifiable.

Integrated vector management for malaria control

Directory of Open Access Journals (Sweden)

Impoinvil Daniel E

2008-12-01

Full Text Available Abstract Integrated vector management (IVM is defined as "a rational decision-making process for the optimal use of resources for vector control" and includes five key elements: 1 evidence-based decision-making, 2 integrated approaches 3, collaboration within the health sector and with other sectors, 4 advocacy, social mobilization, and legislation, and 5 capacity-building. In 2004, the WHO adopted IVM globally for the control of all vector-borne diseases. Important recent progress has been made in developing and promoting IVM for national malaria control programmes in Africa at a time when successful malaria control programmes are scaling-up with insecticide-treated nets (ITN and/or indoor residual spraying (IRS coverage. While interventions using only ITNs and/or IRS successfully reduce transmission intensity and the burden of malaria in many situations, it is not clear if these interventions alone will achieve those critical low levels that result in malaria elimination. Despite the successful employment of comprehensive integrated malaria control programmes, further strengthening of vector control components through IVM is relevant, especially during the "end-game" where control is successful and further efforts are required to go from low transmission situations to sustained local and country-wide malaria elimination. To meet this need and to ensure sustainability of control efforts, malaria control programmes should strengthen their capacity to use data for decision-making with respect to evaluation of current vector control programmes, employment of additional vector control tools in conjunction with ITN/IRS tactics, case-detection and treatment strategies, and determine how much and what types of vector control and interdisciplinary input are required to achieve malaria elimination. Similarly, on a global scale, there is a need for continued research to identify and evaluate new tools for vector control that can be integrated with

Applications of the conserved vector current theory and the partially conserved axial-vector current theory to nuclear beta-decays

International Nuclear Information System (INIS)

Tint, M.

The contribution of the mesonic exchange effect to the conserved vector current in the first forbidden β-decay of Ra E is estimated under the headings: (1) The conserved vector current. (2) The CVC theory and the first forbidden β-decays. (3) Shell model calculations of some matrix-elements. (4) Direct calculation of the exchange term. Considering the mesonic exchange effect in the axial vector-current of β-decay the partially conserved axial vector current theory and experimental results of the process p + p → d + π + are examined. (U.K.)

Feature Vector Construction Method for IRIS Recognition

Science.gov (United States)

Odinokikh, G.; Fartukov, A.; Korobkin, M.; Yoo, J.

2017-05-01

One of the basic stages of iris recognition pipeline is iris feature vector construction procedure. The procedure represents the extraction of iris texture information relevant to its subsequent comparison. Thorough investigation of feature vectors obtained from iris showed that not all the vector elements are equally relevant. There are two characteristics which determine the vector element utility: fragility and discriminability. Conventional iris feature extraction methods consider the concept of fragility as the feature vector instability without respect to the nature of such instability appearance. This work separates sources of the instability into natural and encodinginduced which helps deeply investigate each source of instability independently. According to the separation concept, a novel approach of iris feature vector construction is proposed. The approach consists of two steps: iris feature extraction using Gabor filtering with optimal parameters and quantization with separated preliminary optimized fragility thresholds. The proposed method has been tested on two different datasets of iris images captured under changing environmental conditions. The testing results show that the proposed method surpasses all the methods considered as a prior art by recognition accuracy on both datasets.

Vectorization of Monte Carlo particle transport

International Nuclear Information System (INIS)

Burns, P.J.; Christon, M.; Schweitzer, R.; Lubeck, O.M.; Wasserman, H.J.; Simmons, M.L.; Pryor, D.V.

1989-01-01

This paper reports that fully vectorized versions of the Los Alamos National Laboratory benchmark code Gamteb, a Monte Carlo photon transport algorithm, were developed for the Cyber 205/ETA-10 and Cray X-MP/Y-MP architectures. Single-processor performance measurements of the vector and scalar implementations were modeled in a modified Amdahl's Law that accounts for additional data motion in the vector code. The performance and implementation strategy of the vector codes are related to architectural features of each machine. Speedups between fifteen and eighteen for Cyber 205/ETA-10 architectures, and about nine for CRAY X-MP/Y-MP architectures are observed. The best single processor execution time for the problem was 0.33 seconds on the ETA-10G, and 0.42 seconds on the CRAY Y-MP

Horizontal vectorization of electron repulsion integrals.

Science.gov (United States)

Pritchard, Benjamin P; Chow, Edmond

2016-10-30

We present an efficient implementation of the Obara-Saika algorithm for the computation of electron repulsion integrals that utilizes vector intrinsics to calculate several primitive integrals concurrently in a SIMD vector. Initial benchmarks display a 2-4 times speedup with AVX instructions over comparable scalar code, depending on the basis set. Speedup over scalar code is found to be sensitive to the level of contraction of the basis set, and is best for (lAlB|lClD) quartets when lD  = 0 or lB=lD=0, which makes such a vectorization scheme particularly suitable for density fitting. The basic Obara-Saika algorithm, how it is vectorized, and the performance bottlenecks are analyzed and discussed. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

A vector lattice version of Radström's embedding theorem

African Journals Online (AJOL)

Radström's embedding theorem for 'near vector spaces', which are essentially vector spaces without additive inverses, is extended to embeddings of 'near vector lattices', which are essentially vector lattices without additive inverses, into vector lattices. If the 'near vector space' is endowed with a metric, properties on the ...

Search for intermediate vector bosons

International Nuclear Information System (INIS)

Klajn, D.B.; Rubbia, K.; Meer, S.

1983-01-01

Problem of registration and search for intermediate vector bosons is discussed. According to weak-current theory there are three intermediate vector bosons with +1(W + )-1(W - ) and zero (Z 0 ) electric charges. It was suggested to conduct the investigation into particles in 1976 by cline, Rubbia and Makintair using proton-antiproton beams. Major difficulties of the experiment are related to the necessity of formation of sufficient amount of antiparticles and the method of antiproton beam ''cooling'' for the purpose of reduction of its random movements. The stochastic method was suggested by van der Meer in 1968 as one of possible cooling methods. Several large detectors were designed for searching intermediate vector bosons

On vector fields having properties of Reeb fields

OpenAIRE

Hajduk, Boguslaw; Walczak, Rafal

2011-01-01

We study constructions of vector fields with properties which are characteristic to Reeb vector fields of contact forms. In particular, we prove that all closed oriented odd-dimensional manifold have geodesible vector fields.

Vector fields and gravity on the lattice

International Nuclear Information System (INIS)

Khatsymovsky, V.M.

1988-01-01

The problem of discretization of vector field on Regge lattice is considered. Our approach is based on geometrical interpretation of the vector field as the field of infinitesimal coordinate transformation. A discrete version of the vector field action is obtained as a particular case of the continuum action, and it is shown to have the true continuum limit

Visualizing vector field topology in fluid flows

Science.gov (United States)

Helman, James L.; Hesselink, Lambertus

1991-01-01

Methods of automating the analysis and display of vector field topology in general and flow topology in particular are discussed. Two-dimensional vector field topology is reviewed as the basis for the examination of topology in three-dimensional separated flows. The use of tangent surfaces and clipping in visualizing vector field topology in fluid flows is addressed.

[Orthogonal Vector Projection Algorithm for Spectral Unmixing].

Science.gov (United States)

Song, Mei-ping; Xu, Xing-wei; Chang, Chein-I; An, Ju-bai; Yao, Li

2015-12-01

Spectrum unmixing is an important part of hyperspectral technologies, which is essential for material quantity analysis in hyperspectral imagery. Most linear unmixing algorithms require computations of matrix multiplication and matrix inversion or matrix determination. These are difficult for programming, especially hard for realization on hardware. At the same time, the computation costs of the algorithms increase significantly as the number of endmembers grows. Here, based on the traditional algorithm Orthogonal Subspace Projection, a new method called. Orthogonal Vector Projection is prompted using orthogonal principle. It simplifies this process by avoiding matrix multiplication and inversion. It firstly computes the final orthogonal vector via Gram-Schmidt process for each endmember spectrum. And then, these orthogonal vectors are used as projection vector for the pixel signature. The unconstrained abundance can be obtained directly by projecting the signature to the projection vectors, and computing the ratio of projected vector length and orthogonal vector length. Compared to the Orthogonal Subspace Projection and Least Squares Error algorithms, this method does not need matrix inversion, which is much computation costing and hard to implement on hardware. It just completes the orthogonalization process by repeated vector operations, easy for application on both parallel computation and hardware. The reasonability of the algorithm is proved by its relationship with Orthogonal Sub-space Projection and Least Squares Error algorithms. And its computational complexity is also compared with the other two algorithms', which is the lowest one. At last, the experimental results on synthetic image and real image are also provided, giving another evidence for effectiveness of the method.

Applicability of vector processing to large-scale nuclear codes

International Nuclear Information System (INIS)

Ishiguro, Misako; Harada, Hiroo; Matsuura, Toshihiko; Okuda, Motoi; Ohta, Fumio; Umeya, Makoto.

1982-03-01

To meet the growing trend of computational requirements in JAERI, introduction of a high-speed computer with vector processing faculty (a vector processor) is desirable in the near future. To make effective use of a vector processor, appropriate optimization of nuclear codes to pipelined-vector architecture is vital, which will pose new problems concerning code development and maintenance. In this report, vector processing efficiency is assessed with respect to large-scale nuclear codes by examining the following items: 1) The present feature of computational load in JAERI is analyzed by compiling the computer utilization statistics. 2) Vector processing efficiency is estimated for the ten heavily-used nuclear codes by analyzing their dynamic behaviors run on a scalar machine. 3) Vector processing efficiency is measured for the other five nuclear codes by using the current vector processors, FACOM 230-75 APU and CRAY-1. 4) Effectiveness of applying a high-speed vector processor to nuclear codes is evaluated by taking account of the characteristics in JAERI jobs. Problems of vector processors are also discussed from the view points of code performance and ease of use. (author)

Estimation of Motion Vector Fields

DEFF Research Database (Denmark)

Larsen, Rasmus

1993-01-01

This paper presents an approach to the estimation of 2-D motion vector fields from time varying image sequences. We use a piecewise smooth model based on coupled vector/binary Markov random fields. We find the maximum a posteriori solution by simulated annealing. The algorithm generate sample...... fields by means of stochastic relaxation implemented via the Gibbs sampler....

Exotic composite vector boson

International Nuclear Information System (INIS)

Akama, K.; Hattori, T.; Yasue, M.

1991-01-01

An exotic composite vector boson V is introduced in two dynamical models of composite quarks, leptons, W, and Z. One is based on four-Fermi interactions, in which composite vector bosons are regarded as fermion-antifermion bound states and the other is based on the confining SU(2) L gauge model, in which they are given by scalar-antiscalar bound states. Both approaches describe the same effective interactions for the sector of composite quarks, leptons, W, Z, γ, and V

Vector models in RETRAN-02 MOD 2

International Nuclear Information System (INIS)

Kinnersly, S.R.

1985-06-01

The vector momentum model in RETRAN-02 allows momentum flux to be modelled in two dimensions. Vector models in RETRAN-2 are described, including both the actual implementation in the code and the specification given in the code manual. The vector momentum model is described in detail. Other models which use vector quantities include models for volume average flow, volume average slip velocity, volume average phase velocities and fill junction flows. Both code implementations and code manual descriptions are described and inconsistencies noted. The differences between the standard RETRA-02 Mod 2 version and the Winfrith version RETN2204 are noted. (U.K.)

Vector fields satisfying the barycenter property