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Sample records for legend cancer-suspect agent

  1. Indian Legends.

    Science.gov (United States)

    Gurnoe, Katherine J.; Skjervold, Christian, Ed.

    Presenting American Indian legends, this material provides insight into the cultural background of the Dakota, Ojibwa, and Winnebago people. Written in a straightforward manner, each of the eight legends is associated with an Indian group. The legends included here are titled as follows: Minnesota is Minabozho's Land (Ojibwa); How We Got the…

  2. Rethinking map legends with visualization.

    Science.gov (United States)

    Dykes, Jason; Wood, Jo; Slingsby, Aidan

    2010-01-01

    This design paper presents new guidance for creating map legends in a dynamic environment. Our contribution is a set of guidelines for legend design in a visualization context and a series of illustrative themes through which they may be expressed. These are demonstrated in an applications context through interactive software prototypes. The guidelines are derived from cartographic literature and in liaison with EDINA who provide digital mapping services for UK tertiary education. They enhance approaches to legend design that have evolved for static media with visualization by considering: selection, layout, symbols, position, dynamism and design and process. Broad visualization legend themes include: The Ground Truth Legend, The Legend as Statistical Graphic and The Map is the Legend. Together, these concepts enable us to augment legends with dynamic properties that address specific needs, rethink their nature and role and contribute to a wider re-evaluation of maps as artifacts of usage rather than statements of fact. EDINA has acquired funding to enhance their clients with visualization legends that use these concepts as a consequence of this work. The guidance applies to the design of a wide range of legends and keys used in cartography and information visualization.

  3. The Transitional Legend of Winners

    Directory of Open Access Journals (Sweden)

    Ivan Kovačević

    2016-03-01

    Full Text Available During 2006 a number of stories that featured the motive of great gain under dramatic circumstances were repeatedly told in betting-houses in Kragujevac, a town in Serbia. The main character of these legends is an empoverished victim of transition who, thanks to luck and help of friends, wins a great sum of money betting. Besides describing the preceding transitional "fall" of the winner (getting fired, failing in private enterprise, the legends describe his economical and social prosperity initiated by capital gained through betting (starting succesfull enterprises, buying good shares. Diachronically following other "sudden wealth" legends this transitional legend speaks about the establishing of a new system of values that, in the categories of social promotion, makes up for the old principles that marked the period of socialism.

  4. The Chicano and the Black Legend.

    Science.gov (United States)

    Sanchez, Porfirio

    An historical overview traces the Black Legend about persons of Spanish descent and seeks to demonstrate the influence of the Black Legend on Anglo attitudes towards Mexican Americans. The beginnings of the Black Legend are found in the sixteenth century when European countries in conflict with Spain used Spanish actions during the Sack of Rome,…

  5. Al Zubarah - eine vergessene Legende

    DEFF Research Database (Denmark)

    Kinzel, Moritz

    2014-01-01

    Jahre später auf einem Sechstel der ursprünglichen Siedlungsfläche wiedererrichtet und dann im ausgehenden 19. Jahrhundert / beginnenden 20. Jahrhundert endgültig aufgeben. Die Stadt lebt als Legende im Bewusstsein der katarischen Bevölkerung, doch der Name wird heute nicht mit der Stadtanlage sondern...

  6. The Legend of Louis Pasteur

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 12; Issue 1. The Legend of Louis Pasteur. S Mahadevan. General Article Volume 12 Issue 1 ... Author Affiliations. S Mahadevan1. Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore 560012, India.

  7. The hand in Irish legend and folklore.

    Science.gov (United States)

    Mooney, E E; Prendiville, J B

    1991-06-01

    A brief review of the significance of the hand in the mythology, folklore, and religion of Ireland from ancient times is presented. Many of these accounts are also found in the history and legends of other Celtic countries.

  8. Symbolic Interactionism, Mass Panics and Urban Legends

    Directory of Open Access Journals (Sweden)

    Ivan Kovačević

    2016-02-01

    Full Text Available The constructionist approach to social problems has developed a thesis about mass panics and urban legends as "unconstructed social problems". This thesis, advanced by the American sociologist Joel Best, and his analysis of the urban legend of Halloween sadism, have provided the model for studying three mass panics and two urban legends. The three panics in question are the mass exodus from Kraljevo because of a prophesy that the town would be destroyed in an earthquake, the mass fear of body parts thieves in three villages in Srem, and the panic over the appearance of a cannibal sect in the town of Šabac. The two urban legends involve the rich old emigrant whose acquaintance a child from a poor family made while dialling phone numbers at random, and the thieving postman who set up his own business in Russia with the stolen pension money he had been supposed to deliver.

  9. ["Imperial madness" - truth or legend?].

    Science.gov (United States)

    V Zerssen, D

    2011-03-01

    The notion of "imperial madness" was coined in the historical literature and belles-lettres of the 19th century. Around that time up to the first quarter of the 20th century, it was adopted by a few German psychiatrists. Two of them viewed "imperial madness" as ordinary forms of insanity which became excessive only due to reactions of the social environment. Another one, however, classified it as one of "mental borderland states" in between insanity and normality, although he conceived the final stage of the disorder as a paranoid one. In agreement with the historians he postulated that "imperial madness" resulted from unlimited power of predisposed rulers. In recent times the whole concept of "imperial madness" was referred to the realm of legends by historians of antiquity and other historically interested authors. Yet the existence of the phenomenon cannot be denied. Despite its rarity it has played and is still playing an important role with often catastrophic consequences in various cultures all over the world. Therefore, psychiatrists and other physicians as well as clinical psychologists should be acquainted with it. From a modern point of view, it is not a paranoid disorder but rather a syndrome of addiction-like behavioural excesses representing an intensification of a Hybris syndrome as described by Anglo-Saxon psychiatrists. According to the present authors' view, it should be classified nosologically as a chronic adjustment disorder. In this case, the underlying stresses need to be extended to situations of temptation (here: the temptation to abuse almost unlimited power). © Georg Thieme Verlag KG Stuttgart · New York.

  10. [From teratology to mythology: ancient legends].

    Science.gov (United States)

    Stahl, A; Tourame, P

    2010-12-01

    The mythology of the Greeks and Romans is full of monsters of fiction: giants, cyclops, centaurs, hydras, Gorgons… The accounts of travelers, reproduced in the Natural History of Pline l'Ancien reported the existence, in distant countries, of men with a dog's head (baboons), of men with a single tall foot (sciapode), beings whose face is embedded in the chest (or acephala blemmyes), to which must be added a wide variety of men with no mouth, no nose, or equipped with giant ears or feet turned backwards, as well as hermaphrodites. Teratology reports on monstrous births, which have constituted the factual basis from which the imagination conceived adults whose morphology corresponds to the monsters of legend. Newborns sirenomelia were behind the legend of sciapode and sirens. Cyclopia have inspired the legend of the cyclops. Anencephaly probably explains the description of headless or blemmyes. The genesis of the legend of baboons may have multiple origins: firstly the existence of people suffering from congenital hypertrichosis, on the other hand, the influence of Egyptian mythology where the god Anubis has a dog's head. The acardiac fetus may explain some monstrous forms, features the work of Hieronymus Bosch. The significance of the monsters of legend, their genesis, their persistence through the ages is complex. By approaching teratology, we added a new field of exploration of real monsters of antiquity and Middle Ages. Copyright © 2010. Published by Elsevier SAS.

  11. Bembya Fedorov, Three Legends About Kalmyk Tea

    OpenAIRE

    Okonova, Altana; Churyumov, Anton

    2017-01-01

    Legend One. Kalmyk tea is a present from gods to the Kalmyk people. In the past, the Kalmyks drank kumis, cow milk and spring water only. One day god in the form of an old man descended on earth. When he entered a Kalmyk yurt, he saw a young bride cooking lunch. The old man offered to make Kalmyk tea. Every one in the family liked the new drink. Since then the Kalmyks make this tea and offer the first cup of fresh tea to gods. Legend Two. Upon his arrival in China from Tibet, Bodhidharma spe...

  12. The Onion and "When Legends Die."

    Science.gov (United States)

    Bell, Loren C.

    1984-01-01

    Describes the eight layers in Thomas Black Bull's ("When the Legends Die") journey to spiritual rebirth and stresses that students can easily identify these layers and can thereby achieve a clearer understanding of the relationship between structure and meaning in fiction. (CRH)

  13. Legends of Belogradchik (Strigachev, 2009 [In Bulgarian

    Directory of Open Access Journals (Sweden)

    B. V. Toshev

    2016-07-01

    Full Text Available This slim book contains 11 legends about Belogradchik and its vicinity and people. The book is illustrated. The author of the book is Stefan Strigachev (1935-2000. Additionally, the text of the book is exhilarated by several clever rhymes written also by the author.

  14. The Interethnic and Interreligious Values in Turkish and Crimean Legends

    OpenAIRE

    Anastasiia Zherdieva

    2014-01-01

    The present paper examines interethnic and interreligious values in Turkish and Crimean folk legends. The folklore of both Crimea and Turkey has a multicultural background, which makes both corpuses of texts suitable for research. In the course of the study, a wide range of published Turkish and Crimean legends were reviewed and analysed. There are two deeply-rooted tendencies in the studied legends. First of all, the interethnic and interreligious relationships can be described as ghastly an...

  15. Sangadzhi Kononov, Legends from Dund Khurul

    OpenAIRE

    Kovaeva, Bair; Churyumov, Anton

    2016-01-01

    Legend One. In the past an astrologist calculated the time and place where a boy with the head of a wolf would be born. Upon hearing this terrible news, some worried people went to the prophesized place only to find a woman who was in labor. As soon as the woman gave birth, the newborn who had a wolf’s head set about running around the tent trying to escape from the crowd. The people caught the baby and when they were about to kill him, the baby said, ‘If only had I sucked the milk of my moth...

  16. DVD-d. Shrek Kolmas; Ma olen legend / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2008-01-01

    Lühiarvustused USA 2007.a. filmidele : animafilm "Shrek Kolmas" ("Shrek the Third", režissöörid Chris Miller, Raman Hui) ja ulmefilm "Ma olen legend" ("I Am Legend"; režissöör Francis Lawrence)

  17. Do learners really know best? Urban legends in Education

    NARCIS (Netherlands)

    Kirschner, Paul A.; Van Merriënboer, Jeroen

    2018-01-01

    This article takes a critical look at three pervasive urban legends in education about the nature of learners, learning, and teaching and looks atwhat educational and psychological research has to say about them. The three legends can be seen as variations on one central theme, namely, that it is

  18. The Interethnic and Interreligious Values in Turkish and Crimean Legends

    Directory of Open Access Journals (Sweden)

    Anastasiia Zherdieva

    2014-05-01

    Full Text Available The present paper examines interethnic and interreligious values in Turkish and Crimean folk legends. The folklore of both Crimea and Turkey has a multicultural background, which makes both corpuses of texts suitable for research. In the course of the study, a wide range of published Turkish and Crimean legends were reviewed and analysed. There are two deeply-rooted tendencies in the studied legends. First of all, the interethnic and interreligious relationships can be described as ghastly and cursed. Thus, antagonists in the legends are often from ethnic minorities or strangers in relation to domestic ethnic groups. However, if the texts are analysed thoroughly, we can see that there are important sacred cultural values at the core of the legends, including values of life, health, and divinity.

  19. Book Review: Adolf Hitler. Legende, mythe, werkelijkheid | Ploeger ...

    African Journals Online (AJOL)

    Abstract. Book Title: Adolf Hitler. Legende, mythe, werkelijkheid. Book Author: Werner Maser. Uitgeverij De Arbeiderspers, Amsterdam, 1973, pp. 531. Met aantekeninge [pp. 429 - 506] en bibliografie [pp. 507 - 531].

  20. "Legends Od Rockil" kõlab Ulthima Thule

    Index Scriptorium Estoniae

    2007-01-01

    2. detsembril Rocca ala Mare suurhallis toimuvast rocki suurüritusest "Legends of Rock", kontserdil esinevatest muusikutest. Ansamblist Brides In Bloom, kavast korraldada ühiskontsert koos ansambliga Aides 10. novembril, esitamaks ansambli Ulthima Thule loomingut

  1. LEGEND, a LEO-to-GEO Environment Debris Model

    Science.gov (United States)

    Liou, Jer Chyi; Hall, Doyle T.

    2013-01-01

    LEGEND (LEO-to-GEO Environment Debris model) is a three-dimensional orbital debris evolutionary model that is capable of simulating the historical and future debris populations in the near-Earth environment. The historical component in LEGEND adopts a deterministic approach to mimic the known historical populations. Launched rocket bodies, spacecraft, and mission-related debris (rings, bolts, etc.) are added to the simulated environment. Known historical breakup events are reproduced, and fragments down to 1 mm in size are created. The LEGEND future projection component adopts a Monte Carlo approach and uses an innovative pair-wise collision probability evaluation algorithm to simulate the future breakups and the growth of the debris populations. This algorithm is based on a new "random sampling in time" approach that preserves characteristics of the traditional approach and captures the rapidly changing nature of the orbital debris environment. LEGEND is a Fortran 90-based numerical simulation program. It operates in a UNIX/Linux environment.

  2. The Mozart effect: Tracking the evolution of a scientific legend

    OpenAIRE

    Bangerter Adrian; Heath Chip

    2004-01-01

    Theories of the diffusion of ideas in social psychology converge on the assumption that shared beliefs (e.g., social representations, rumours and legends) propagate because they address the needs or concerns of social groups. But little empirical research exists demonstrating this link. We report three media studies of the diffusion of a scientific legend as a particular kind of shared belief. We studied the Mozart effect (ME), the idea that listening to classical music enhances intelligence....

  3. Erzurum in the Turkmen Version of Koroglu Legend

    Directory of Open Access Journals (Sweden)

    Mustafa Serbes

    2016-03-01

    Full Text Available In the Turkmen version of Koroglu Legend, there exist lots of country, city and place names belonging to the Turkish world and neighboring folks. The places in the legend are not only composed of Turkmen lands and neighbors, but there are other extraordinary places like Kaf Mountain as well. The hero of the legend, Koroglu, has connections with neighboring places because of various reasons. In the most of the sections, Koroglu organizes wars against the neighboring countries and cities. He imposes a tax on some of those countries and cities. Arzılum (Erzurum is also one of the cities in which Koroglu is interested. Although it’s far from Turkmen geography, Erzurum takes place in the Turkmen version of the legend. The city is described in details. In the most sections of the legend, the name and the characteristics of the city, particularly “Erhasan and Tellihan” take place. In this study, the materials related to Erzurum, which is located in twenty one sections of the Turkmen version of Koroglu Legend, have been analyzed. The information given about the city has been evaluated, particularly by moving from the section of “Erhasan and Tellihan”.

  4. Urban Legends – American and/or Global Folklore

    Directory of Open Access Journals (Sweden)

    Ivan Kovačević

    2016-03-01

    Full Text Available Development of modern technology, foremostly that of the Internet, has made feasible and, up to now, unimaginable reciprocity in the field of anthropological research. If only the wealthy scientific communities were be privy to a global research, while the rest of the world was deprived, the fast flow of information has made possible that each of its users be in the possession of relevant information for the study of, until now, unapproachable turfs, such as the US. Urban legends epitomize a paramount illustration of the possibility of examining American folklore from any world viewpoint, not least Serbia. That is possible for urban legends generated in America, are disseminated through the classic channels of globalization, and through the aforementioned World Wide Web. The study of urban legends activates reflexivity of traditional anthropological subject – diffusion, in the shape of dissecting reception and evolution of pursuit of generating native urban legends. Such a stance is taken by the study of urban legends in Serbia.

  5. The Legend of Queen Sheba, the Solomonic Dynasty and Ethiopian ...

    African Journals Online (AJOL)

    The existence of the Orthodox Tewahido church and other religious ceremonies, the presence of Beta Israel, the names of people like Makeda or Sheba and organizations such as the Sheba Miles are all testimonies to the legend living in the present Ethiopian communities. It purported to explain how the Ethiopian ruling ...

  6. The Legend of Queen Sheba, the Solomonic Dynasty and Ethiopian ...

    African Journals Online (AJOL)

    Nekky Umera

    ceremonies, the presence of Beta Israel, the names of people like Makeda or ... from Solomon and through him from Abraham and the early patriarchs. ..... the status of women in ancient. Ethiopian society. (kensey.schema.ca/GWH-Lecture 5b.htm). The legend debunks the popular dictum of seeing the role of women as just.

  7. The legend of laphet: A Myanmar fermented tea leaf

    Directory of Open Access Journals (Sweden)

    Thazin Han

    2015-12-01

    Conclusion: Fermentation is the traditional method. Epigallocatechin gallate is a powerful constituent of laphet for human health. Its caffeinated effect is also popular in Myanmar society. This study will contribute to understanding Myanmar fermented tea leaves and spread the legend of laphet around the world.

  8. Edison's Modern Legend in Villiers' L'Eve future

    Directory of Open Access Journals (Sweden)

    Ana Oancea

    2012-03-01

    International and Electrical Expositions of the 1870s and 1880s. Villiers’ depiction of the protagonist as astute showman does not, however, amount to a criticism of his technological abilities. Instead, the author’s emphasis on these characteristics goes to solidify his legend as a modern, unique tale of economic success through applied science.

  9. The Flight to Egypt in Slavic Etiological Legends about the Trees

    Directory of Open Access Journals (Sweden)

    Tatyana A. Agapkina

    2018-03-01

    Full Text Available The paper examines Slavic etiological legends on the Flight to Egypt plot. These legends feature trees and bushes growing on the way of Maria’s and Joseph’s flight to Egypt. Some of these plants helped Christ and his parents escape while others betrayed them to the Herod’s army. Virgin Mary endowed the plants with “positive” or “negative” qualities respectively, as either a reward or a sign of damnation. The author analyzes folk legends that were familiar to Eastern, Western, and Southern Slavs; points out which plants were mentioned in the legends and describes the circle of plant symbols; enlists themes, types and motifs of these legends and compares them to other apocryphal legends that had the same source, namely the Gospel of Pseudo-Matthew. The Gospel of Pseudo-Matthew seemed to be influential mainly in Western Slavia where the main core of etiological legends was recorded.

  10. Legends of Organ Theft: The Moral Dilemma of Contemporary Society

    Directory of Open Access Journals (Sweden)

    Dragana Antonijević

    2016-03-01

    Full Text Available Legends and rumors of organ theft became a global phenomenon in the beginning of the 80s, with the information originating from the "Third world" countries. Victims where poor and powerless, typically children. The rumor engaged a series of actions from anthropologists, NGO’s and media trying to ascertain their validity. Before long, the world was divided into two camps: on the one hand where those who believed the rumors, condemning the West for its exploitation of the underdeveloped and the poor that lead to organ theft from healthy individuals, to satisfy the needs of the rich white patients; and the other faction that, through the data, tried to negate these assertions as unfounded and illogical. At the beginning of the 90s, similar reports surfaced in the highly developed societies of Europe and the USA. Unlike the rumors, these where developed, structured narratives with specific content – legends of kidney theft, whose victims were left alive. Internet has brought about the expansion of such stories. None the less, they remained the under-analyzed, not attracting the attention of the politically minded and militant anthropologists who, in the Third world rumors, recognized material for their anti-colonial and mediatory theories. Few have tried to explain the legend and folklore origins of the First world narratives and to ascertain their function without insightful analysis. That is why I engaged in a semantic analysis of the legend in the context of the highly developed societies, with the intent of exposing their message of a deep moral dilemma concerning organ donation. I found that their hidden meaning is "revolutionary", not an inversion that I thought previously, but in accordance with the public discourse that encourages voluntary and legal donations, from cadaver as from living donors, wich is real disadaptive problem for those soceties. I proposed such a meaning by analysing the most unusual and astonishing element in the

  11. Tolerance or Assimilation: The Legends of the Chinese Restaurant and "The Gypsy's Tavern"

    Directory of Open Access Journals (Sweden)

    Ivan Kovačević

    2016-02-01

    Full Text Available Studying urban legends, the French folklorist Véronique Campion-Vincent posed the question of whether some of the more recent legends preach tolerance. The "elevator incident" or "swallowed ticket" legends display a different attitude to Others from that found in classic xenophobic urban legends. This different attitude is also to be found in two legends recorded in Serbia, namely, the legend of the Chinese restaurant and the legend of "The Gypsy's Tavern". An analysis of the two legends shows that the ambiguity of "tolerance legends" does not arise from the fact that they speak about a xenophobic environment while at the same time having a denouement that "preaches" tolerance, but rather from the fact that the "preaching" relates to those Others who have gone through a process of acculturation, who have been assimilated and who have accepted the rules of "our" culture. These legends do not preach tolerance towards the Otherness of Others but towards Others who are striving to become or have managed to become "Us".

  12. The Legends of the Serpent Island in the Danube Delta

    Directory of Open Access Journals (Sweden)

    Tetyana Shevchuk

    2015-08-01

    Full Text Available The report presents a variety of ancient legends, connected with the cult of Achilles on the Serpent (Snake Island, located in 35 km far from the Danube Delta in the territorial waters of Ukraine. The sources of ancient legends are the essay of Flavius Arrian “Periplus Ponti Euxini (maritime guide”, Flavius Philostratus dialogue “On Heroes” (Heroikos, as well as the outlines of Arctinus of Miletus, Maximus of Tyre and Romanian folklore. The imageries of Achilles Pontarchis cult on the Serpent Island (in ancient times – Levka Island, White Island, Island of the Blessed, Fidonisi, Ilan-Ada, Sherpilor disclose the peculiarities of his worship in Scythia and Dacia.

  13. Coyote and the Crane--A Legend of the Yakimas.

    Science.gov (United States)

    George, Larry

    Written in plain terms, printed in large type, and accompanied by illustrations, this legend of the Yakima Indians tells of how the crane came to be; it is the story of how Coyote turns a man into a crane because the man would not share his catch of fish. "In the old days people shared things. It was our way of life. If a person was hungry…

  14. I Would Have Eaten You Too : Werewolf Legends in the Flemish, Dutch and German Area

    OpenAIRE

    de Blécourt, W.

    2007-01-01

    A geographical approach to werewolf legends results in the identification of a major werewolf area, stretching from mid-Germany into the Netherlands and Belgium-despite profound differences in the intensity of collecting the legends. Within this area there were people who were experiencing nightly encounters, especially with back-riding werewolves, and they advised each other about how best to overcome the beasts. Migratory legends, such as the Werewolf Lover/Husband and the Hungry Farmhand, ...

  15. Anna Sangadzhi-Goryaeva, A Legend About Lightning

    OpenAIRE

    Kovaeva, Bair; Babaev, Andrei

    2016-01-01

    Anna’s mother was born in the village of Khar-Tolga in Yashkul’skiy rayon. There, lightning, thunder and dust storms were frequent occurrences. Anna heard from her mother that she should not be afraid of lightning. According to a legend, once upon a time a god descended on earth but could not ascent back to the skies. He was helped by a pair of helping hands from Anna’s maternal clan. Since then lightning never harms people from this clan. One day when Anna lived in the village of Chilgir lig...

  16. I Would Have Eaten You Too : Werewolf Legends in the Flemish, Dutch and German Area

    NARCIS (Netherlands)

    de Blécourt, W.

    2007-01-01

    A geographical approach to werewolf legends results in the identification of a major werewolf area, stretching from mid-Germany into the Netherlands and Belgium-despite profound differences in the intensity of collecting the legends. Within this area there were people who were experiencing nightly

  17. The Legend of Jump Mountain: Narrative Dispossession of the Monacan in Postcolonial Virginia

    Science.gov (United States)

    Vest, Jay Hansford C.

    2012-01-01

    In north central Virginia there is a local tale--The Legend of Jump Mountain, which purports to explain the origins of the Hayes Creek Indian Burial Mound. A highly romantic legend, it immortalizes post colonial intertribal warfare during the early nineteenth century while ignoring the antiquity of the mound and the local descendants of its…

  18. The Ordinary and the Fabulous: An Introduction to Myths, Legends and Fairy Tales. Second Edition.

    Science.gov (United States)

    Cook, Elizabeth

    Written for teachers, for students who intend to be teachers or librarians, and for storytellers in general, this book interprets the familiar legends and tales (Greek, Scandinavian, German, and Celtic myths and legends; Arthurian romances; the Old Testament; and fairy tales) and describes how they can best be told to children. Parallel accounts…

  19. Spatial legend compatibility within versus between graphs in multiple graph comprehension.

    Science.gov (United States)

    Riechelmann, Eva; Huestegge, Lynn

    2018-02-01

    Previous research has shown that spatial compatibility between the data region and the legend of a graph is beneficial for comprehension. However, in multiple graphs, data-legend compatibility can come at the cost of spatial between-graph legend incompatibility. Here we aimed at determining which type of compatibility is most important for performance: global (legend-legend) compatibility between graphs, or local (data-legend) compatibility within graphs. Additionally, a baseline condition (incompatible) was included. Participants chose one out of several line graphs from a multiple panel as the answer to a data-related question. Compatibility type and the number of graphs per panel were varied. Whereas Experiment 1 involved simple graphs with only two lines/legend entries within each graph, Experiment 2 explored more complex graphs. The results indicated that compatibility speeds up comprehension, at least when a certain threshold of graph complexity is exceeded. Furthermore, we found evidence for an advantage of local over global data-legend compatibility under specific conditions. Taken together, the results further support the idea that compatibility principles strongly determine the ease of integration processes in graph comprehension and should thus be considered in multiple-panel design.

  20. Russia's imperial blood: was Rasputin not the healer of legend?

    Science.gov (United States)

    Kendrick, John M L

    2004-09-01

    The only son of Russia's last Tsar, a great-grandson of Queen Victoria, continues to be used as the favorite example of the X-linked inheritance of hemophilia, in spite of the fact that this popular historical diathesis has never been confirmed by any form of modern medical laboratory testing. Certain to be controversial, a new study of the symptoms that were witnessed by those who were closest to the teenaged Russian heir now raises the possibility that his blood disorder might well have been something other than hemophilia. The key to discovering Tsarevich Alexei's true diagnosis is found in those now legendary allegations that the infamous "Mad Monk", Grigory Rasputin, had possessed a power of healing that was somehow responsible for the young boy's mysterious history of spontaneous recoveries. If we are to accept the popular diagnosis of history and call it a clotting factor deficiency, then the boy's now famous sudden recoveries will remain a complete mystery. The so-called "Mad Monk" Rasputin, as a direct result of the revolutionary propaganda of the time, is then overblown into a larger-than-life legend. If, however, we are to change the diagnosis and call it a platelet disorder, then the air is let out of the legend, and Rasputin is revealed to have been nothing more than a very ordinary middle-aged Siberian hippie who did not possess any healing powers at all. Copyright 2004 Wiley-Liss, Inc.

  1. Serial killers, spiders and cybersex: Social and survival information bias in the transmission of urban legends.

    Science.gov (United States)

    Stubbersfield, Joseph M; Tehrani, Jamshid J; Flynn, Emma G

    2015-05-01

    This study uses urban legends to examine the effects of the social information bias and survival information bias on cultural transmission across three phases of transmission: the choose-to-receive phase, the encode-and-retrieve phase, and the choose-to-transmit phase. In line with previous research into content biases, a linear transmission chain design with 60 participants aged 18-52 was used to examine the encode-and-retrieve phase, while participants were asked to rank their interest in reading the story behind a headline and passing a story on for the other two phases. Legends which contained social information (Social Type), legends which contained survival information (Survival Type), and legends which contained both forms of information (Combined Type) were all recalled with significantly greater accuracy than control material, while Social and Combined Type legends were recalled with significantly greater accuracy than Survival Type legends. In another study with 30 participants aged 18-22, no significant differences were found between legend types in either the choose-to-receive phase or the choose-to-transmit phase. © 2014 The British Psychological Society.

  2. Some Case Studies on How Media Constructs Olympic Legends

    Directory of Open Access Journals (Sweden)

    Karl Lennartz

    2009-12-01

    Full Text Available During the entire history of the modern Olympic Games, from their renaissance in 1896, when the firsth edition had been heldin Athens and until the Olympic Games in Berlin in 1936, the present paper makes an analyse of the real facts and of thelegends created around them. The sports journal and the other publications are important factors in the distorsion of the realityand keeping the legend. From the athletes heros like Spiridon Louis, the first winner of the marathon and the myth buildaround the way of winning this race , to the story of the 100m won by Jesse Owens at 36 Olympic Games who have been heldin Berlin and the fact that Hitler refused to shake the hand of the Olympic champion, the purpose of this paper is to combat themyths developed since. The facts are substantiated by using the chronological datas, using the notes and minutes of meetings,as well using photographic means.

  3. Legends of Students’ "Clever Answers": Criticism or Affirmation of the Educational System?

    Directory of Open Access Journals (Sweden)

    Jana Baćević

    2016-03-01

    Full Text Available This paper represents an analysis of a group of urban legends from US universities, gathered from a number of web sites and in certain cases compared with analogous examples from Serbia. These legends concentrate around the motif of "clever answers", in which students use witty or otherwise unconventional means to solve problems or answer questions during exams or other forms of knowledge examination, and usually end up being rewarded for their creativity. The analysis of the formal structure of these legends, as well as their possible functions, indicates that, on the one hand, legends of "clever answers" can represent a form of criticism of the higher education system, but on the other actually aid its reproduction and reinforce its role in the social order. Finally, the implications of this interpretation are investigated in the context of contemporary global transformations of higher education.

  4. RUSSIAN LEGENDS IN THE HISTORICAL TALES BY M. MAKAROV

    Directory of Open Access Journals (Sweden)

    Tatiana V. Fedoseeva

    2015-11-01

    Full Text Available The article analyses the  works by  M. Makarov, one  of  the  littleknown Russian authors of  the fi rst third of  the  19th century. There is  an  interest to  the author’s works due to  the controversy of  the  genre specifi city of Russian prose of the 1830-s and the topicality of the Orthodoxoriented governmental way of  thinking, which is  expressed in  his  works. The  collection “Stories from the  Russian folk tales” targets folklore as  the form of expression of the national spirit and ethics. The historical, toponymical and ethnogenetic legends of Vladimir, Novgorod, Ryazan and Moscow lands form the plot of the stories of the collection. At the poetic and stylistic levels the article reveals the correspondence of the analyzed stories to Karamzin’s model of  a  sentimental pre-Romantic tale of  the  1800-s. Its typological specifi city consists in  a  broken plot line; in  special attention to  a  person’s destiny; in the “Gothic anthropologism”, which asserts the unity of human morals of the past and of the present. The fictionalized plots of the legends in Makarov’s tales serve to accentuate the Orthodox-based spiritual guidelines and moral values of the nation. As a result, the undertaken study substantiates the special type of  folklorism of  Russian historical prose in  the fi rst third of  the  19th  century. The combination of  the  features of  oral poetical and literary genres comprises its peculiarity

  5. Ingmar Bergman, the biographical legend and the intermedialities of memory

    Directory of Open Access Journals (Sweden)

    Maaret Koskinen

    2010-12-01

    Full Text Available Ingmar Bergman (1918–2007 wrote his autobiography The Magic Lantern (Laterna magica, 1987 5 years after he had finished his film career with Fanny and Alexander, his last feature made for the cinema screen. This arguably marked the second stage of his strictly literary career, the first being his plays for the stage in the 1940s. The Magic Lantern is of interest from an intermedial perspective in its forthright theatricalization or cinematization of the written text and the self-conscious performativity of its authorial voice. Of particular interest is the way the narrator turns into a kind of distanciated autobiographical witness, which in turn reminds the reader of the inherent narrative split in the autobiographical genre between the enunciating subject speaking from the present, and the described subject, the younger self in the past. In doing so the narrator seems to turn language itself into a performative venue: the medium of words becomes a theatrical stage or a cinematically charged mise-en-scène for memory as such.This is of course not only stylistically elegant, for what can be more natural than a film- and theater director who, as the very title of the autobiography announces, turns memories into cinematic and theatrical performances? But even more interesting is the extent to which Bergman in doing so seems to conjur forth his biographical legend, reminding the reader of who is in charge of text: the narrator becomes the director of the text, so to speak, lighting and setting the stage.Besides this artful approach, Bergman also clearly fictionalized his life in other ways, which is corroborated by the private note books and original manuscripts that the writer of this paper has gained access to.

  6. The Legend of the Nativity and Childhood of St. Onuphrius the Great

    Directory of Open Access Journals (Sweden)

    Voitenko Anton

    2017-02-01

    Full Text Available The article examines the provenance and circulation of the Legend of the nativity and childhood of St. Onuphrius the Great. The author suggests that originally the Legend was part of a hybridised version of Life of St. Onuphrius, which was presumably compiled in Italy in the 14th century. The probable cause of the appearance of the Legend was a desire to supply information on his childhood which was absent from the original version of his Life. Thereafter, one of the Italian editions of the hybridised version of the Life, which was compiled and published in the middle of the 17th century by Paolo Regio, became the basis (directly or indirectly for French, Polish and Church Slavonic versions. The Legend contained in a Polish hybridised version, which was published by Revd. Jósef Pietkiewicz at the end of the 17th century, came to be, in its turn, the basis for a separate story of the nativity and childhood of St. Onuphrius compiled by St. Dimitry of Rostov in Church Slavonic. It was published in the 4th volume of his Lives of Saints (Kiev, 1705. In the next editions, the text of the Legend was removed for censorship reasons, but it continued to be copied (in the first hand, by Old Believers. In Slavonic manuscripts, a shortened version also occurs.

  7. ROLE AND USE OF THE PHOTO-LEGEND IN RUSSIAN AND GERMAN MEDIA DISCOURSE

    Directory of Open Access Journals (Sweden)

    Lenkova, T.A.

    2016-06-01

    Full Text Available The article is devoted to one of the most interesting themes of modern linguistics – media-linguistics. The author has researched the function and the role of the photo-legend. In the article we try to present the difference in the opinion of Russian and German scientists about how the journalists can use the photo-legend and how they can not do it. The Russian Journalists often use the photo archives offering to the absolutely different contexts one and the same illustration. This way to our mind the editors and the journalists of papers have to many possibilities for manipulation of the public opinion, this way is dangerous and very subjective. The German journalists deal with this theme more serious, they are sure that the photo and the photo-legend must concern to only one article, it is a guarantee of authentic and synonymous. The author is of opinion the competence of the photo-legend use depends on many different aspects, for example, on the client of the article, on the paper, on the readers. We are sure that the subject of the photo-legend, its role, function and use will be researched in future.

  8. The Ordinary and the Fabulous: An Introduction to Myths, Legends, and Fairy Tales for Teachers and Storytellers.

    Science.gov (United States)

    Cook, Elizabeth

    Written for teachers, librarians, students, parents, and other storytellers, this book emphasizes the value and enchantment which children can find in the fabulous stories of four main European traditions--Greek myths and legends, Northern myths and legends, Arthurian Romances, and fairy tales. The four chapters contain (1) discussions of myths,…

  9. 75 FR 68012 - Notice of Intention To Cancel Registrations of Certain Transfer Agents

    Science.gov (United States)

    2010-11-04

    ... 8505250 Legends Financial Holding, Inc 8505534 Liberty Transfer Company 8405474 Manchester Benefits Group... status of each of the transfer agents listed in the Appendix, based on the facts it has, the Commission... Transfer Agents LLC 8406151 Guarantee Services Corp 8406145 Hola Corp 8406047 Howard Johnson & Company...

  10. ROLE AND USE OF THE PHOTO-LEGEND IN RUSSIAN AND GERMAN MEDIA DISCOURSE

    OpenAIRE

    Lenkova, T.A.

    2016-01-01

    The article is devoted to one of the most interesting themes of modern linguistics – media-linguistics. The author has researched the function and the role of the photo-legend. In the article we try to present the difference in the opinion of Russian and German scientists about how the journalists can use the photo-legend and how they can not do it. The Russian Journalists often use the photo archives offering to the absolutely different contexts one and the same illustration. This way to our...

  11. Last Chance Well : legends and legacies of Leduc No. 1

    International Nuclear Information System (INIS)

    Hunter, B.

    1997-01-01

    In 1995, Beatrice Hunter began a series of interviews with oil-patch personalities focusing on their lives and the times surrounding the pivotal events of the Leduc No. 1 oil discovery in 1947. In 1946, Imperial Oil Ltd. was facing a decision which would be of great importance to Alberta and to the rest of Canada. In the preceding 25 years, Imperial had spent millions of dollars on exploration and had drilled 133 dry holes. When the company asked Vern Hunter to drill its 134th hole on the Canadian prairies, few people knew that Imperial's board of directors had decided that this was to be the company's last try at finding oil, and that the jobs of everyone in the crew would depend on the results. As we all know, the 134th hole, that was to become famous as Leduc no. 1, was successful and its success opened the door to potential treasures beyond anyone's expectations. Indeed, the Leduc find can be considered to have been the most important economic event in Canada, certainly in Alberta, during the post-war years, an event that set in motion an industrial expansion in Alberta that has never been equaled in Canada before or since. Despite the implication of its title, this book is not a chronological history of Alberta's oil industry. Rather, it is a human interest account of the lives and times of the people who were directly involved in bringing in Leduc no. 1, and to a lesser extent, the lives and times of some other individuals whose lives have been unalterably affected by the rapidly developing industry during its formative years. Their stories, anecdotes and tall tales form the legend of the Leduc Field. The value of the book lies in its ability to bring to life for the benefit of future generations the spirit, the colour and the memory of the conditions that existed then. That the stories are preserved in the words of the individuals themselves, makes the book particularly useful as an introduction to better understanding of the pioneering spirit of the West

  12. “The Birds of Clay”: An Apocryphal Motif in Folklore Legends

    Directory of Open Access Journals (Sweden)

    Olga V. Belova

    2015-08-01

    The fairly large group of folk legends with apocryphal motifs, occurring in different Slavic traditions from the 19th to the 21st centuries, thus testifies not only to the continued relevance of the biblical plots for oral culture, but also to the importance of the Apocrypha for the broadcasting and preservation of biblical stories in the folk tradition.

  13. Exploring Social Studies through Multicultural Literature: "Legend of the St Ann's Flood"

    Science.gov (United States)

    Fry, Sara Winstead

    2009-01-01

    The search for literature that is of high quality and interest, is written at age-appropriate levels for adolescent readers, addresses social studies topics, and presents multicultural perspectives can be daunting. "Legend of the St Ann's Flood" is a fiction trade book that meets all of these criteria. Its setting in Trinidad and Tobago…

  14. The legend of the Caboclo D’água: a folkcommunicative enunciative trajectory

    Directory of Open Access Journals (Sweden)

    Simome dos Santos Mendes

    2013-10-01

    Full Text Available Truth or not, the fact is that the Caboclo D’água’s legend, present in various Brazilian cities, is more alive than never. From 2009 up till now, the legend transformed itself into a mediatic phenomenon, with one of the most immediate implications being the inauguration of a two-meter-high statue at Barra Longa’s city entrance (Minas Gerais/Brazil and the creation of a Ghost Hunter Association, dedicating itself to capturing the Caboclo D’água - the association even offering a R$ 10,000.00 reward to who succeeds in taking a picture of the creature. Moreover, the present work aims at analyzing, from the discursive point of view, the modern (reconstruction of the legend through mediatic means and dwellers claiming to have seen the creature. Furthermore, we intend to reflect on the impacts of mediatization suffered by the legend, from its discursive construction point of view. The theoretical contribution we used is linked to Foucault’s archive concept (1995, folkcommunication (BELTRÃO, 1967, folkmedia (LUYTEN, 2002, and Bravin’s reflections (2011 on the legend’s mediatic repercussion in newspapers and on the Internet.

  15. 15 CFR Appendix D to Part 30 - AES Filing Citation, Exemption and Exclusion Legends

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false AES Filing Citation, Exemption and... Appendix D to Part 30—AES Filing Citation, Exemption and Exclusion Legends I. USML Proof of Filing Citation AES ITN Example: AES X20060101987654. II. AES Proof of Filing Citation subpart A § 30.7 AES ITN...

  16. «I Am Legend»: comparison of the fictional virus infection and Rabies virus

    Directory of Open Access Journals (Sweden)

    José Francisco CAMACHO AGUILERA

    2016-04-01

    Full Text Available Using the movie I am legend (2007 by, the rabies virus infection is reviewed in this article, given its strong resemblance to the fictional disease created in this film caused by the virus Krippin. A review of history, virus characteristics, viral transmission, clinical manifestations, diagnostics, mortality, treatment and prevention, are presented and are contrasted with the film.

  17. LEAGUE OF LEGENDS GAME CHARACTERS SELECTION PROBLEMS OF THE MULTICRITERIA DECISION MAKING METHOD AND SOLUTION

    OpenAIRE

    ERCAN, Merve; YILDIRIM, Meral; OTURAK, Çiğdem; EREN, Tamer

    2018-01-01

    Strategy games occupy a very important place in gaming industry. In this study, characterselection is made according to the rival team which is created by developing scenarios for Summoner's Rift inLeague of Legends (LOL) strategy game and Howling Abyss modes. In order to solve the problem, AnalyticalHierarchy Process (AHP), TOPSIS and PROMETHEE methods are utilized from multicriteria decision makingmethods in Summoner's Rift and Howling Abyss mode. For the problem, five alternative...

  18. “The Birds of Clay”: An Apocryphal Motif in Folklore Legends

    OpenAIRE

    Olga V. Belova

    2015-01-01

    The article describes the adaptation of the apocryphal Gospels motif—the revival of clay birds by Jesus—in the folk traditions of Eastern and Western Slavs. The texts of folk legends demonstrate not only the active inclusion of apocryphal motifs in oral narratives, but they also incorporate the motifs’ biblical contexts and they emphasize themes that are close to everyday life and that reflect local history. The folklore texts analyzed here are from different regions of the Slavic world (Russ...

  19. The rise and rise of e-Sports, tournament videogaming and the League of Legends

    OpenAIRE

    Grundy, David

    2015-01-01

    The final of the 2015 World Championship of League of Legends, a fantasy-themed, real-time strategy videogame, is being streamed worldwide by the BBC. Like the most popular of sporting occasions such as football tournaments and the Olympic Games, video gaming tournaments attract thousands of spectators to arenas and millions more watching live broadcasts. So how did videogames cross from being a bedroom activity to a highly competitive tournament sport with serious prizes to match?

  20. Fallen star legends and traditional religion of Japan: an aspect of star lore

    Science.gov (United States)

    Goto, Akira

    2015-08-01

    Japanese star lore is a complex mixture of animism, Buddhism, Shinto-ism, Confucianism and folk beliefs. Although some studies have been done on rituals concerning constellation developed in esoteric Buddhism (e.g. Journal Culture and Cosmos, Vol. 10 no 1 and 2), studies on other aspects of Japanese star lore are limited, in particular, to the English audience.In historic literatures, there often mentioned abnormal astronomical phenomena, such as, eclipse, meteors and comets. In this paper, I will discuss the possibility of reference to these astronomical phenomena in order to talk about some historical facts.In western part of Japan, there are Shinto shrines and Buddhistic temples that are said to be built as monuments of fallen stars. Usually fallen stars were divided into three, and a trio of shrines/temples are said to be the remnants of this phenomenon. Similar legends are found in Kudamatsu (that means "fallen pine=pine where stars fallen") of Yamaguchi Prefecture, Bisei-cho (that means "beautiful star") of Okayama Prefecture, Hoshida (that means "rice field or village of star") shrine of Osaka, and also Hoshida shrine of Nagoya.The purpose of this presentation is not to argue whether fallen star legend was truly astronomical phenomenon, such as, meteor or not. Instead, I will discuss why similar legends have been talked concerning the origin of particular shrines or temples. Citing Eliade who related gorge and alchemy producing spark to astronomical phenomena, I will disclose the possibility to relate these astronomical legends to the coming of the naturalized Japanese from Korean Peninsula who introducd forge to Japan abound 5 to 6 centuries.

  1. Eastern Tales for Western Readers: A Combination of Traditions within D. Mamin-Sibiryak’s Legends

    Directory of Open Access Journals (Sweden)

    Tuliakova, Natalia

    2016-09-01

    Full Text Available The paper analyses Mamin-Sibiriak’s Legends (1898 cycle, which appeared at the time when legends in Russia were at the peak of popularity. The cycle is a masterful stylization of Asian folk tales belonging to some of the minorities of the Russian Empire, and it fuses together Oriental and Occidental literary and geopoetic traditions. The background of the cycle creation and an analysis of the Asian and European roots of the legends reveal the ways in which the two cultures are combined by the author. Mamin-Sibiryak uses Oriental stylization, typical of the folk-lore of minor ethnic groups of the Trans-Urals, on the levels of language and imagery. His artful employment of linguistic and poetic devices such as foreign words, alien names and realias, zoomorphic metaphors and similes, as well as concepts and sets of values not typical of European mentality, misled his contemporaries into thinking that he had published some collected folk material. However, the writer created his own plots, following patterns and motifs mostly characteristic of both Western and Eastern cultures. There are similarities between the plots and the motifs of the cycle and those of the European Romanticism, Buddhism, Indian epics, and Biblical scenes. Consequently, Mamin-Sibiryak’s choice of plots may be aimed at identifying some basic similarities between these traditions. A study of the cycle proves that the impact on the legends by A. Schopenhauer’s philosophy, which exploits ideas shared by Eastern and Western cultures, contributes to the interaction of Occidental and Oriental cultures within the cycle on the underlying levels, though the connotation of some Eastern motifs is contradictory to the Western tradition. While creating the legends, the author did not aim just at making the Russian reader acquainted with the folklore of minority groups. Rather, the chosen ‘alien’ form was intended to help the reader forget about everyday life and perceive some

  2. Toward a Generative Model of Legend: Pizzas, Bridges, Vaccines, and Witches

    Directory of Open Access Journals (Sweden)

    Timothy R. Tangherlini

    2017-12-01

    Full Text Available We propose a generative model of the legend. The model is elaborated based on two case studies, the first of contemporary storytelling related to vaccination on parenting blogs, and the second of historical storytelling related to witchcraft and folk healing in nineteenth century Denmark. The model reveals the interdependent levels of the multiscale model, solving a problem of poor fit related to many two level models of folklore genre structure. The model supports the study of rumor, and the dynamics of storytelling, including the hyperactive transmission state of “viral” stories.

  3. Inevitable recidivism--the origin and centrality of an urban legend.

    Science.gov (United States)

    Lave, Tamara Rice

    2011-01-01

    This paper examines the pervasive conviction that sex offenders - particularly child molesters - will continue to re-offend. This belief in inevitable recidivism turns out to be absolutely essential to both the justification for, and the structure of, the sexually violent predator laws. When actual evidence of sex offender recidivism is examined, however, a huge gap exists between what is assumed and what the data actually show because most sex offenders do not in fact re-offend. Thus there is a galaxy of sexually violent predator laws and an entire branch of Supreme Court jurisprudence that is founded upon a demonstrable urban legend. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. [Divine cadavers: gender, medical discourse, and anatomical collections in the legend of Pedro González de Velasco].

    Science.gov (United States)

    del Pozo, Alba

    2016-01-01

    This paper examines the relationship between the public image of Pedro Gonzólez de Velasco (1815-1882), famous for his anatomical collections and his Anthropological Museum, founded in 1875 in Madrid, and the popular legend related to the death, embalming and exhumation of his daughter Concepción. The doctor who is committed to the nation becomes a mad scientist, and his official biography is transformed into an urban legend. Beyond the merely anecdotal, I show how the aesthetics associated with female corpses and artificial women organize cultural imaginaries, bringing together medical discourses and literary and artistic representations.

  5. Herman Merivale’s black legend: rethinking the intellectual history of free trade imperialism

    Directory of Open Access Journals (Sweden)

    Daniel Rood

    2008-12-01

    Full Text Available Focusses on the lectures and theories of economist and colonial bureaucrat Herman Merivale on the imperial transition of British colonialism from slave labour to free labour, and toward free trade, in 1839. Author specifically shows how Merivale propagated the free trade imperialism of the reformed British Empire by using the "Black Legend" way of thinking, i.e. criticizing Spanish colonialism, to caricaturize the second British Empire, and thus justify imperial policy reforms. Author elaborates on this Black Legend tradition, going back to writings of Las Casas, and how it served as justification for "better" imperialisms of other colonial powers than Spain, and how Merivale's views followed this tradition. He shows how Merivale as part of this criticized the mismanagement, slavery, brutality, mercantilism, and the concentration of power and wealth in Cuba and other Spanish colonies, as negative examples contrasted to the British approach. Author points out, however, how Merivale's views were in part paradoxical and ambiguous, as he favoured a social hierarchy and an imperial authoritarianism limiting free labour.

  6. The SiteLegend: twelve components of a new strategy for providing website documentation.

    Science.gov (United States)

    Weiler, R M; Pealer, L N

    2000-04-01

    The World Wide Web continues to evolve dramatically with an estimated 57 million users in the United States. Some two-thirds of Internet users in the United States searched for health information the past year, with 90% indicating they found the information they sought. Thus, health and medical information represents the single most popular topic on the Web, surpassing all other categories. Yet, few measures exist to ensure the accuracy of information provided to children and adults through such sites. Some existing quality control measures such as assessment instruments, authoritative guidelines, and seal of approval systems provide screening mechanisms, but none of these measures guarantees protection for users. This article proposes a new approach to ensuring full and accurate disclosure of information about a website. Referred to as a SiteLegend, the approach uses a hyperlink to fully inform consumers regarding 12 essential components of website. This article describes each of the 12 essential components, then provides an example of an active online link that illustrates actual use of the SiteLegend hyperlink approach.

  7. Fact, Myth and Legend in Matthew Arnold’s Westminster Abbey

    Directory of Open Access Journals (Sweden)

    Tadej Braček

    2007-06-01

    Full Text Available The paper deals with the multilayered elegy “Westminster Abbey;” which was not given a lot of attention by Matthew Arnold’s critics. The poem is dedicated to Arnold’s life-long friend Dean Stanley; who was; like Arnold himself; “a child of light.” The term refers to their common fight against Philistinism in the English society of the time. As the poem is about a real person; it contains real data; such as excerpts from Stanley’s life; described in the form of praise. However; the poem also introduces the old Saxon legend of consecration of the Abbey; namely the consecration by the light; performed by the First Apostle (St Peter himself. In addition to the legend; Arnold also used some classical Greek allusions to depict the late Dean’s character. In one of the allusions; Stanley is associated with Demophon; whose immortality was never achieved due to the fault of another human; and in the second he is transformed into an everlasting oracle of the Abbey using the Trophonius; a builder of Delphi; metaphor. All elements of the poem form a homogenous eulogy; making it worthwhile reading for English scholars and students; and possibly a candidate for the English poetic canon.

  8. TOPONYMIC LEGENDS OF KAZAKH TURKS KAZAK TÜRKLERİNİN TOPONOMİK EFSANELERİ

    Directory of Open Access Journals (Sweden)

    Seyfullah YILDIRIM

    2012-01-01

    Full Text Available Throughout history humans have always made up some thoughts and theories when they haven’t been able to understand what is going around in external world. In this process of defining and recognition some ideas about the origin, creation and composition of the world were developed. This course of thinking ended up with the formation of oral literature. One of the genres of this literature is myth. Legends are short narratives that are believed to be true, that have no stylistic features and that have educational aspects to give moral messages. They dictate us about the consequences of our inappropriate behaviors. Kazakh Turks name the term “legend” with the words “aŋız”, “äpsana” or “hikayat”. The academicians, although some of them offer some different classifications, generally classify the legends of Kazakh Turks under two topics as historical and toponymic legends. This paper examines twenty toponymic legends that were created to explain the names of regional places and places of water. Thus it is aimed to clarify the importance of these legends in Turkish culture and mythology. İnsan dış dünyayı tanıma ve tanımlama sürecinde çaresiz kaldığı durumlarda çevresini kendisine göre düşünüp değerlendirerek yapı, köken ve oluşumla ilgili birtakım düşünceler geliştirmiştir. Zamanla değişen ve gelişen bu düşünce serüveni sözlü türlerin oluşmasını sağlamıştır. İşte bizim yaşadığımız dünyayı tanımlama ve anlamlandırma sürecimizin ürünü olan türlerden birisi de efsanedir. Kısa, üslup özelliklerinden yoksun, gerçek olduğuna inanılan, terbiyevîkarakterdeki anlatmalardır ve bize davranışlarımızın sonucuyla ilgili olarak birtakım çıkarımlarda bulunur. İnceleme konusu olarak ele alınan Kazak Türklerinde efsane kavramı genel olarak “aŋız”, “äpsana” ve “hikayat” gibi kavramlarla ifade edilir. Kazak Türklerinin efsaneleriyle ilgili

  9. Africa’s Legends: digital technologies, aesthetics and middle-class aspirations in Ghanaian games and comics

    NARCIS (Netherlands)

    Pijnaker, T.; Spronk, R.

    2017-01-01

    Africa’s Legends is a mobile application developed by the Ghanaian game development company Leti Arts in 2012. The app consists of one game and two comics about eight ‘African’ superheroes. This article aims to give insight into the intersection of digital technologies and social class; it

  10. Learning Form and Function by Dance-Dramatizing Cultural Legends to Drum Rhythms Wearing Student-Made Animal Masks

    Science.gov (United States)

    Gray, Phyllis; Rule, Audrey C.; Kirkland Holmes, Gloria; Logan, Stephanie R.; Alert, Andrea L.; Mason, Cynthia A.

    2016-01-01

    This study examined the self-efficacy in science, art, dance, and music; attitudes concerning contributions of people of various ethnic/cultural groups; and science learning of students involved in an after-school arts-integrated science enrichment project. Students dramatized three traditional animal legends from African, Native American, and…

  11. How Paiutes science education is influenced by their myths and legends

    Science.gov (United States)

    Capistrant, Susan Lee

    The Paiutes science education is influenced by their myths and legends. To the People, these are their truths, just like the Bible is to the Christians, the Torah is to the Jews and the Koran is to the Muslims. The more connected the Native person is to his/her traditional beliefs, the more likely they are to reject certain aspects of science, (personal communication, 7/3/2012). The worldview of the Paiutes also influences how they perceive science. To the Paiute, the earth is alive and everything has a soul. The birds, animals and plants give them information about their environment. Gregory Cajete stated that "Education is an art of process, participation and making connection. Learning is growth and life process; and Life and Nature are always in relationship!" Learning for the Native American is a form of "culture shock" because the White man's school is so different. The Native person's culture is passed on from generation to generation through oral traditions, such as songs, stories, legends, myths, their history, language and traditions. Indigenous science needs to be mixed with Western science. The student's knowledge base has to be acknowledged. The teacher of these students need to be familiar with their values and not expect the same as they would from the other students. The teacher should become a culture broker to help the Paiute student cross back and forth between the two sciences. The curriculum should have these ideas included in it. The best way to change the curriculum is to include the elders, the parents, grandparents, community leaders, and others. They can help fuse the Paiutes' culture into the science classroom and help it merge with Western science. The results of the research questions showed that the Paiutes need to have their values, their myths and legends, included in their science classrooms. The Paiute student's worldview is different from that of Western science. Therefore, the help of a "border crossing" teacher is encouraged to

  12. Constructing a Soil Class Map of Denmark based on the FAO Legend Using Digital Techniques

    DEFF Research Database (Denmark)

    Adhikari, Kabindra; Minasny, Budiman; Greve, Mette Balslev

    2014-01-01

    Soil mapping in Denmark has a long history and a series of soil maps based on conventional mapping approaches have been produced. In this study, a national soil map of Denmark was constructed based on the FAO–Unesco Revised Legend 1990 using digital soil mapping techniques, existing soil profile...... observations and environmental data. This map was developed using soil-landscape models generated with a decision tree-based digital soil mapping technique. As input variables in the model, more than 1170 soil profile data and 17 environmental variables including geology, land use, landscape type, area...... of wetlands, digital elevation model and its derivatives were compiled. The predicted map showed that Podzols and Luvisols were the most frequent soil groups, covering almost two-thirds of the area of Denmark. Geographically, Podzols occupied a major portion of western Denmark, where the soils have developed...

  13. Die Entstehung einer Legende. Alexander von Humboldts angeblicher Ausspruch über Salzburg.

    Directory of Open Access Journals (Sweden)

    Robert Hoffmann

    2006-04-01

    Full Text Available Article in German, Abstract in English.This paper sheds light on the history of the quotation “I regard the environs of Salzburg, Naples, and Constantinople as the most beautiful on earth”, which is usually attributed to Alexander von Humboldt. The author shows that Humboldt’s alleged praise of Salzburg first appeared around 1870, and thus the quotation cannot be regarded as authentic. As a local legend it was meant to connect permanently the famous name of Humboldt with that of the growing centre of tourism. The circumstances under which the quotation found its way into the literature remain to be investigated; however, it seems clear that this can be seen as a typical example of what Eric Hobsbawm has called „invention of tradition“. Invented traditions – this might comfort the tourist industry of Salzburg – have particularly long lives.

  14. Rumors and Realities: Making Sense of HIV/AIDS Conspiracy Narratives and Contemporary Legends

    Science.gov (United States)

    2015-01-01

    The social context of the early HIV/AIDS epidemic in the United States provided fertile ground for rumors about transmission. Today, however, rumors about HIV/AIDS persist only within the African American public. Focus group and public discourse data reveal the content and distribution of HIV/AIDS origin and conspiracy rumors. Rumor and contemporary legend theory allows reinterpretation of rumors as a measure of trust between the African American public and health professionals, not as evidence of ignorance or of historical racial oppression. To improve public health results in the African American community, HIV/AIDS efforts must acknowledge the sources and meanings of rumors, include rumors as a measure of trust, and address the underlying distrust that the rumors signify. PMID:25393166

  15. Transactional Reading in EFL Learning: A Path to Promote Critical Thinking through Urban Legends

    Directory of Open Access Journals (Sweden)

    Mariela Leal Hernandez

    2015-10-01

    Full Text Available This article reports the research methodology and the findings of an action-research study conducted with a group of EFL eleventh graders’ at a public school in Bogotá. The study aimed at helping learners develop critical thinking through the implementation of the Transactional approach to reading. Individual and social transactions during the reading process of several urban legends enabled learners to discuss social conflicts that were also related to their lives, including, for instance, social irresponsibility, violence, drug consumption, and dishonesty. Data analysis from teachers’ observations, students’ opinions in an interview, and artifacts (workshops completed in a pedagogical intervention show that the students fostered critical thinking. The main findings indicate that they criticized human behaviors, generated solutions to conflicts, and planned and produced new knowledge based on previous information. An equal significant finding is that they became critical learners when they used the foreign language.

  16. Clinical empathy and narrative competence: the relevance of reading talmudic legends as literary fiction.

    Science.gov (United States)

    Davidson, John H

    2015-04-01

    The "curative potential" in almost any clinical setting depends on a caregiver establishing and maintaining an empathic connection with patients so as to achieve "narrative competence" in discerning and acting in accord with their preferences and best interests. The "narrative medicine" model of shared "close reading of literature and reflective writing" among clinicians as a means of fostering a capacity for clinical empathy has gained validation with recent empirical studies demonstrating the enhancement of theory of mind (ToM), broadly conceived as empathy, in readers of literary fiction. Talmudic legends, like that of Rabbi Judah's death, are under-appreciated, relevant sources of literary fiction for these efforts. The limitations of narrative medicine are readily counterbalanced by simultaneously practiced attention to traditional bioethical principles, including-especially-beneficence, non-maleficence, and autonomy.

  17. The Legend of Hot Tar or Pitch as a Defensive Weapon

    DEFF Research Database (Denmark)

    Atzbach, Rainer

    2015-01-01

    In popular culture and even in academic discourse surrounding castles, hot tar pitch has been depicted as a widespread defensive weapon. The identification of "machicoulis" (machicolations) as an architectural provision for pouring down liquid tar pitch goes back to the early days of castle...... research. In reality, this way of fighting can only be seen as a legend, i.e. a story with only a relative truth at its core. This paper will examine the origin of this historical tradition and its archaeological and architectural sources. The chemical and physical properties of tar pitch and its...... production and use during the Middle Ages will be discussed with special focus on the application of tar pitch as an ingredient in medieval and post-medieval thermal weapons (especially Greek Fire, the firebomb and the fire arrow). The punishment of tarring and feathering will also be considered...

  18. Urban Legends and Paranormal Beliefs: The Role of Reality Testing and Schizotypy

    Directory of Open Access Journals (Sweden)

    Neil Dagnall

    2017-06-01

    Full Text Available Recent research suggests that unconventional beliefs are locatable within a generic anomalous belief category. This notion derives from the observation that apparently dissimilar beliefs share fundamental, core characteristics (i.e., contradiction of orthodox scientific understanding of the universe and defiance of conventional understanding of reality. The present paper assessed the supposition that anomalous beliefs were conceptually similar and explicable via common psychological processes by comparing relationships between discrete beliefs [endorsement of urban legends (ULs and belief in the paranormal] and cognitive-perceptual personality measures [proneness to reality testing (RT and schizotypy]. A sample of 222 volunteers, recruited via convenience sampling, took part in the study. Participants completed a series of self-report measures (Urban Legends Questionnaire, Reality Testing subscale of the Inventory of Personality Organization, Revised Paranormal Belief Scale and the Schizotypal Personality Questionnaire Brief. Preliminary analysis revealed positive correlations between measures. Within schizotypy, the cognitive-perceptual factor was most strongly associated with anomalistic beliefs; disorganized and interpersonal produced only weak and negligible correlations respectively. Further investigation indicated complex relationships between RT, the cognitive-perceptual factor of schizotypy and anomalistic beliefs. Specifically, proneness to RT deficits explained a greater amount of variance in ULs, whilst schizotypy accounted for more variance in belief in the paranormal. Consideration of partial correlations supported these conclusions. The relationship between RT and ULs remained significant after controlling for the cognitive-perceptual factor. Contrastingly, the association between the cognitive-perceptual factor and ULs controlling for RT was non-significant. In the case of belief in the paranormal, controlling for proneness to RT

  19. Sibelius: Pohjola's Daughter; Night Ride and Sunrise; Four Legends from Kalevala (Lemminkäinen Suite). Gothenburg Symphony Orchestra, Neeme Järvi / Brian Hunt

    Index Scriptorium Estoniae

    Hunt, Brian

    1997-01-01

    Uuest heliplaadist "Sibelius: Pohjola's Daughter; Night Ride and Sunrise; Four Legends from Kalevala (Lemminkäinen Suite). Gothenburg Symphony Orchestra / Neeme Järvi. Deutsche Grammophon 453 426-2; 70:37 DDD

  20. La legende de Dona Marinha: mythologie et génealogie

    Directory of Open Access Journals (Sweden)

    Delpech, F.

    2008-12-01

    Full Text Available The medieval legend of Dona Marinha is an account of the origins of the galician family of the Marinhos. It tells of the rape of a mysterious and mute seamaid by a knight, and of her gradual integration into human society.
    This tale belongs to the subgroup of genealogical traditions based on mythical backgrounds,which were in use in the peninsular culture at the end of the Middle Ages. It differs however from the melusinian type, with which it only has some slight analogies.
    In this legend is experimentally tested an imaginary model of resolution of the conflictive duality which opposes Nature and Culture, exogamy and assimilation, masculine predominance and matrilineal trends. This model is embodied by a type of marriage in which the mediation of filiation conveys a softening and, at last, an elimination of the inconveniences of hyper-exogamy.

    La leyenda medieval de Doña Marinha, en la que se explica el origen del linaje gallego de los Marinhos, cuenta el rapto por un caballero de una mujer marina misteriosa y muda y la progresiva integración de la misma en la sociedad humana.
    Este relato forma parte del subgrupo de las tradiciones genealógicas de fondo mítico que florece en la península hacia el final de la Edad Media. Sin embargo se distingue claramente del tipo de las leyendas «melusinianas », con las que sólo comparte analogías superficiales. En esta leyenda se pone a prueba e ilustra un imaginario modelo experimental de resolución de la dualidad conflictiva entre Naturaleza y Cultura,, exogamia y asimilación, poder masculino y orientación matrilineal, y se propone, al nivel mítico, un tipo de alianza matrimonial mediatizada en el que la filiación y el ritual ayudan a mitigar, y finalmente anular, los inconvenientes de una exogamia excesiva.

  1. Kentucky pharmacists' opinions of the potential reclassification of pseudoephedrine as a legend drug

    Science.gov (United States)

    Monson, Kathleen E.; Freeman, Patricia R.; Goodin, Amie J.; Talbert, Jeffery; Blumenschein, Karen

    2015-01-01

    Objectives To collect and analyze Kentucky pharmacists' opinions of the effectiveness of current methamphetamine precursor controls, to analyze proposed legislation to make pseudoephedrine (PSE) a legend drug, and to analyze the potential impact of such legislation on pharmacy practice and patients. Design Descriptive, nonexperimental survey study. Setting Kentucky; June through October 2012. Participants 431 Kentucky community pharmacists. Intervention Mailed survey. Main outcome measures Perceived efficacy of current methamphetamine precursor controls, anticipated impact on individual pharmacy practices and patients of proposed legislation to make PSE available by prescription only, and current opinions about the proposed legislation. Results Analysis of 431 community pharmacists showed that approximately 77% believed proposed legislation to make PSE available by prescription only would be effective in reducing methamphetamine abuse and methamphetamine-related laboratory incidents, with 56.2% indicating support for the proposed legislation. Pharmacists practicing in chain pharmacies were 2.9 times more likely to support the legislation than pharmacists practicing in independent pharmacies. Additional factors influencing pharmacist support included Kentucky region of practice, anticipated impact on time spent on PSE activities, pharmacy profit, methamphetamine abuse, and methamphetamine-related laboratory incidents. Pharmacists practicing in regions of Kentucky associated with higher methamphetamine abuse appear to more strongly support the proposed legislation. Conclusion Pharmacists are at the frontline of PSE distribution. Gaining a better understanding of issues surrounding the distribution of PSE will enhance the likelihood that future legislation may be crafted to reduce methamphetamine production, laboratory incidents, and abuse while minimizing inconvenience and cost. PMID:25063261

  2. How to boost shallow geothermal energy exploitation in the adriatic area: the LEGEND project experience

    International Nuclear Information System (INIS)

    Francesco, Tinti; Annamaria, Pangallo; Martina, Berneschi; Dario, Tosoni; Dušan, Rajver; Simona, Pestotnik; Dalibor, Jovanović; Tomislav, Rudinica; Slavisa, Jelisić; Branko, Zlokapa; Attilio, Raimondi

    2016-01-01

    The evaluation, monitoring and reduction of the heating and cooling consumptions are topics of increasing importance. One promising technology is the geothermal heat pump. Despite its undoubted advantages compared to fossil fuels in terms of RES production, CO 2 reduction and primary energy savings, there are still significant barriers for the creation of sustainable local markets. Many regions present similar conditions in terms of climate, geology, hydrogeology, infrastructure and political conditions. Because of the context-driven nature of shallow geothermal systems, similarities should be taken into account and strategies shared across borders to foster the introduction and exploitation of shallow geothermal energy. Focusing on the results of the LEGEND Project, this paper presents an attempt at creating an interregional strategy for the widespread introduction of geothermal heat pumps in the Adriatic area, which includes EU and non-EU countries. The multi-level approach adopted (a combination of desk studies on the transferability potential, pilot plants across the regions and programs to involve, educate and train stakeholders) allowed to set up the strategy. Therefore, different actions are proposed to stimulate the development of the market, whose interconnection across the Adriatic can accelerate the achievement of the main energy and climate targets for all the countries involved. - Highlights: •The Interregional Adriatic strategy for shallow geothermal energy is presented. •The strategy speeds up renewable energy introduction in border countries. •Geological, climate, market and political similarities must be taken into account. •The preparatory action is the creation of trained market and supply chain.

  3. El videojuego League of legends y su efecto en memoria de trabajo visual y solución de problemas

    OpenAIRE

    Leyva-Rodríguez, Jesús Eduardo; Varela-García, Juan David

    2016-01-01

    El propósito de este estudio es medir los efectos que tiene el videojuego League of Legends en los procesos cognitivos de memoria de trabajo visual (MVT) y solución de problemas (SP). Para medir dichos efectos se implementó un diseño pre test-post con un grupo experimental y uno control, compuestos cada uno por siete participantes, en donde se evaluaron los procesos previamente mencionados utilizando los cubos de Corsi para MVT y las matrices del WAIS III para SP. Después de realizar los resp...

  4. Göç Ve Ergenekon Destanlarında Mitostan Ütopyaya Yolculuk A Passage From Mythos To Utopia In The Legends Of Migration And Ergenekon

    Directory of Open Access Journals (Sweden)

    Ebru ŞENOCAK

    2013-03-01

    Full Text Available The legends are historical mirrors that reflect the cultural life,national conscious and memory of a nation with a literary pleasure. Thelegends of Migration and Ergenekon that constitute the basis of Easternliterature are the products of experiences produced by society’s memoryto struggle against the West by the aim of examining the identity searchand causes of migration. These narrations in which centenaryexperiences are kept alive in oral tradition from one generation to theother are historical, mythological and cultural heritages lightening ourfuture by the past.The legends of migration and Ergenekon tell how a nation thatcannot hold on its history, cultural values, on its “sacred stone”,becomes homeless. Those legends are woven with many mythologicalsymbols that attach a nation to its past. The symbols in the legendssuch as tree, mountain, water, fire, iron, dream etc. are like a road mapby which we can examine the life story and historical data of Turkishnation. This road map can only become clear by clarifying the contentsof conscious and unconscious. Tree, mountain and water symbolswhich are the myths of birth and re-birth are eternal power sourcesfeeding the life energy of the legend. The cases of appearing ofmythological mother who exists from the beginning to the end of thelegend, are the symbols selected by the public memory to transmit thesensitivity of legend spirit to the reader. Those mythological elements,which lead the way for the hero by giving meaning to his sacredjourney, give a potential strength to the legend that is a stop-and-thinkplace.In this study, in the light of mythological symbols existing in thelegends of migration and Ergenekon, we will examine the search forculture and identity under the subtitles such as leaving thefather/mother land, the process of enlightment, turning back to thefather/mother land, and mythological rebirth.

  5. Stopped hearts, amputated toes and NASA: contemporary legends among healthy volunteers in US phase I clinical trials.

    Science.gov (United States)

    Fisher, Jill A

    2015-01-01

    The first stage of testing new pharmaceuticals in humans is referred to as a phase I clinical trial. The purpose of these studies is to test the safety of the drugs and to establish appropriate doses that can later be given to patients. Most of these studies are conducted under controlled, in-patient conditions using healthy volunteers who are paid for their participation. To explore healthy volunteers' experiences in clinical trials, an ethnographic study was conducted at six in-patient phase I clinics in the USA. In addition to the observation of clinic activities (from informed consent procedures to dosing to blood draws), 268 semi-structured interviews were conducted, 33 with clinic staff and 235 with healthy volunteers. Drawing on this dataset, this article explores healthy volunteers' exchange of contemporary legends about phase I clinical trials. In addition to potentially scaring the listener and communicating distrust in the medical community, these incredible stories help participants cope with perceived stigma and establish a gradient of risk of trial participation, creating potential boundaries to their participation in medical research. The article argues that contemporary legends play a productive role in society, shaping how people view themselves and others and influencing their decisions about risky activities. © 2015 The Author. Sociology of Health & Illness © 2015 Foundation for the Sociology of Health & Illness/John Wiley & Sons Ltd.

  6. The Coronary Tree of the Anatomical Machines of the Prince of Sansevero: The reality of a legend.

    Science.gov (United States)

    Michele, Sara Di; Mirabelli, Francesca; Gregorio, Giovanni; Lama, Diana; Paolisso, Giuseppe; Galzerano, Domenico

    2015-01-01

    During the 18 th century in Naples, Raimondo di Sangro, Prince of Sansevero, gave definitive form to the family chapel, the so-called "Cappella San Severo". The chapel houses not only extraordinarily beautiful and spectacularly detailed statues but also two human skeletons known as anatomical machines ("Macchine Anatomiche") in the basement. These two skeletons, a man and a pregnant woman, are entirely surrounded by their own circulatory system, just as they were suddenly and mysteriously, fixed. Legend, believed as truth until few years ago, tells that Prince Raimondo had prepared and injected an unknown embalming substance in their blood vessels convicting them to eternal fixity. Most recent investigations, however, demonstrated that while the bones are authentic, the blood vessels are actually an extraordinary artifact, even though the perfect reproduction of the coronary vascular tree, including congenital malformations in detail, raises some doubts about the technique used by the Prince. The dreadful aspect of these two skeletons appears to be in strident contrast with the classic beauty of the statues, which glorifies and celebrates the ideal of morphology. Conversely, the two "Anatomical Machines", protagonists of legends and superstitions since centuries, represent a marvelous example of science and art.

  7. Classification of acid sulphate soils of Finland according to Soil taxonomy and the FAO/Unesco legend

    Directory of Open Access Journals (Sweden)

    M. YLI-HALLA

    2008-12-01

    Full Text Available In order to place acid sulphate soils (a.s. soils of Finland in an international context, five pedons from cultivated a.s. soils from Liminka, Ylistaro and Laitila on the western coast of Finland were analyzed and classified according to Soil Taxonomy and the revised legend of the FAO/Unesco Soil Map of the World. Three of the pedons (Liminka 1 and 2, Laitila 1 had sulfuric horizons within 50 cm of soil surface and qualify as Typic Sulfaquepts. One pedon (Ylistaro had a sulfuric horizon at the depth of 100-150 cm and was classified as a Sulfic Cryaquept. The fifth pedon (Laitila 2 did not have either a sulfuric horizon or sulfidic materials, but it had a pH

  8. Native Legends in Juan María Gutiérrez and Adolfo Berro´s Poetry

    Directory of Open Access Journals (Sweden)

    Eugenia Ortiz Gambetta

    2016-12-01

    Full Text Available This paper aims to consider how Caicobé and Liropeya´s legends had fictionalized in Adolfo Berro´s “Yandubayú y Liropeya (año de 1574” (1840 and Juan M. Gutiérrez´s “Caicobé” and “Irupeya” (1843. These pieces are linked to other poems, plays and novels from Argentina and Uruguay. All of its was based on the work Argentina y conquista del Río de la Plata (1602 by M. del Barco Centenera and use its ethnographic topics to construct the River Plate identity. These works make up the imagery of the “mythology of absence” in relation to the Charruas and Guarani people, modeller speeches of Buenos Aires and oriental fiction.

  9. Antibiotic Agents

    Science.gov (United States)

    ... Superbugs and Drugs" Home | Contact Us General Background: Antibiotic Agents What is an antibacterial and how are ... with the growth and reproduction of bacteria. While antibiotics and antibacterials both attack bacteria, these terms have ...

  10. Amasya Taş Kesilme Efsaneleri ve Motifleri Üzerine On Amasya Petrifaction Legends and Motives

    Directory of Open Access Journals (Sweden)

    Tuğrul BALABAN

    2013-09-01

    Full Text Available The wealth of topics of the the type of legends brings with thedifficulity of making a common definition. Variety of topics exceptfolklore interest many different disciplines. Each field’s definition oflegend in accordance with its own view, thought and perceptionresulted in seeing different dimensions. For this reason, descriptions oflegend can be made by sequencing the significant characteristics of thespecies. Because, legend is more than one thing at the same time.Narratives express thousands of years of experience that reason ofreflections of past cultural experiences to present belief and especiallythey supplied from the mythological legends and named theaforementioned fed and formation of the shape of the change in theconversion. In this way, the stages in the adventure of life of thecommunity to which they belong and they reflect the effects of thevalues they have today.In this study, to present 19 petrifaction which is located in theprovince of Amasya and the public recognition of the trail around theproperty that composed of several practices is aimed. Fixing legendsgenerally located outside of farmland and steep areas. There stonesexhibit topographical differences in the form of requiring explanation onthe field. For this reason, they are tried to mean by analogy most of thetime. Petrifaction legends tell the strain in a stone, rock or mountainformation, and they explained the origin. In this sense, the function ofreporting and disclosure are fulfilled.In the study, when exhausted remedies to get rid of an unwantedsituation of 19 petrifaction legends that compiled by us in the provinceof Amasya, it is mentioned converting to stone rather than surrender tothe enemy or downgrade unwanted wishing to get rid of the unwantedsituation status. Efsane türünün konu zenginliği beraberinde ortak bir tanım yapma güçlüğünü de getirir. Konularının çeşitliliği halkbilimi dışında pek çok farklı disiplinin ilgisini çeker. Her

  11. How did Popular Science Become a Legend? On the linguistic communication of “Science Culture” book series in 1990s Taiwan from the approach of text analysis

    Directory of Open Access Journals (Sweden)

    Ruey-Lin Chen

    2018-01-01

    Full Text Available Commonwealth Publishing Co. in Taiwan has published a series of popular science books, named Science Culture, since 1991. This series has achieved great success in publication and in marketing and up to the present has published over 164 volumes and sold out a great number of hard copies. It is well regarded as a publication legend. How did it succeed? What strategies has it adopted to become such a legend? This paper shows that the series’ success depends on two strategies: exciting subjects and strengthening the first impression. This research applies three related tactics or techniques publishing scientific biographies, literary rhetoric, and using romanticizing titles to realize two strategies of the series. This paper reveals these strategies and techniques by investigating the writing style of books in the series, comparing the titles of the series with other titles of popular science books before 1990, and conducting interviews with the editors of that series.

  12. Trading Agents

    CERN Document Server

    Wellman, Michael

    2011-01-01

    Automated trading in electronic markets is one of the most common and consequential applications of autonomous software agents. Design of effective trading strategies requires thorough understanding of how market mechanisms operate, and appreciation of strategic issues that commonly manifest in trading scenarios. Drawing on research in auction theory and artificial intelligence, this book presents core principles of strategic reasoning that apply to market situations. The author illustrates trading strategy choices through examples of concrete market environments, such as eBay, as well as abst

  13. Radioprotective Agents

    Directory of Open Access Journals (Sweden)

    Ilker Kelle

    2008-01-01

    Full Text Available Since1949, a great deal of research has been carried out on the radioprotective activity of various chemical substances. Thiol compounds, compounds which contain –SH radical, different classes of pharmacological agents and other compounds such as vitamine C and WR-2721 have been shown to reduce mortality when administered prior to exposure to a lethal dose of radiation. Recently, honey bee venom as well as that of its components melittin and histamine have shown to be valuable in reduction of radiation-induced damage and also provide prophylactic alternative treatment for serious side effects related with radiotherapy. It has been suggested that the radioprotective activity of bee venom components is related with the stimulation of the hematopoetic system.

  14. Update to the legend of the reconnaissance soil map of Espírito Santo state and the implementation of Geobases interface for data usage in GIS

    Directory of Open Access Journals (Sweden)

    Alexson de Mello Cunha

    2016-12-01

    Full Text Available The objective of this study was the upgrade of soil mapping units defined in surveys published by the Radambrasil/ IBGE in 1983 and 1987, with the main focus on the clas - ses of soils. To accomplish this, data from representative soil profiles of those surveys were used to classify them in the current Brazilian Classification System. The mapping units which do not have representative profiles were updated based solely on the direct correlation between the denomination used in the old and current classification. This work has also updated the legend of the reconnaissance soil map. The layer of information related to soil, in shape format, containing an attribute table with data regarding mapping units and the respective updated legends (taxonomy, symbols and colors is currently available and can be downloaded by the general public using the Geobases browser. A specific geographic interface for the partners of Geobases dedicated to soil studies has also been created. This interface allows the analysis, acquisition and input of new data, which contributes to the non-duplication of efforts and financial resources on activities of surveying, registering and maintenance of geospatial database related to soils in the State

  15. Agent Building Software

    Science.gov (United States)

    2000-01-01

    AgentBuilder is a software component developed under an SBIR contract between Reticular Systems, Inc., and Goddard Space Flight Center. AgentBuilder allows software developers without experience in intelligent agent technologies to easily build software applications using intelligent agents. Agents are components of software that will perform tasks automatically, with no intervention or command from a user. AgentBuilder reduces the time and cost of developing agent systems and provides a simple mechanism for implementing high-performance agent systems.

  16. Competing agents in agent-mediated institutions

    OpenAIRE

    Plaza, Enric; Arcos, Josep Ll.; Noriega, Pablo; Sierra, Carles

    1998-01-01

    Social processes and agent interaction always take place in a specific context. A school of thought in social studies analyses them in the framework of institutions. We present in this paper the notion of agentmediated institutions and show how it is relevant for multi-agent systems (MAS) in general and, more specifically, for MAS that include human agents and software agents involved in socioeconomic interactions. We show how the social interactions of human and software agents taking place ...

  17. Legender om Norden

    DEFF Research Database (Denmark)

    Jensen-Rix, Robert William

    2015-01-01

    Gennem Middelalderen og indtil nyere tid har Skandinavien altid fremstået som et land i det fjerne - et udkants-Europa, om man vil. Hvis Skandinavien blev omtalt, var det ofte i forbindelse med de brutale vikingetogter der hærgede kontinentet og ikke mindst England... Weekendavisen, Sektion: 4...

  18. Living Legends: Effectiveness of a Program to Enhance Sense of Purpose and Meaning in Life Among Community-Dwelling Older Adults.

    Science.gov (United States)

    Chippendale, Tracy; Boltz, Marie

    2015-01-01

    We investigated the therapeutic benefits (i.e., sense of purpose and meaning in life) of the Living Legends program, which includes life review writing and an intergenerational exchange, compared with life review writing alone, for community-dwelling older adults. This study was a randomized controlled trial with a connected qualitative component. We analyzed quantitative data using independent-samples t tests and written descriptions of program experiences using Collaizi's qualitative methodology; we then used a triangulation protocol to integrate the qualitative and quantitative data. For participants in the writing workshop plus intergenerational exchange, sense of purpose and meaning in life increased significantly (ppurpose and meaning in life, a factor known to prevent cognitive loss and disability, compared with life review writing alone. Copyright © 2015 by the American Occupational Therapy Association, Inc.

  19. Agility: Agent - Ility Architecture

    National Research Council Canada - National Science Library

    Thompson, Craig

    2002-01-01

    ...., object and web technologies). The objective of the Agility project is to develop an open agent grid architecture populated with scalable, deployable, industrial strength agent grid components, targeting the theme 'agents for the masses...

  20. Mobile Agent Security

    National Research Council Canada - National Science Library

    Jansen, Wayne

    1998-01-01

    Mobile agent technology offers a new computing paradigm in which a program, in the form of a software agent, can suspend its execution on a host computer, transfer itself to another agent-enabled host...

  1. Interacting agents in finance

    NARCIS (Netherlands)

    Hommes, C.; Durlauf, S.N.; Blume, L.E.

    2008-01-01

    Interacting agents in finance represent a behavioural, agent-based approach in which financial markets are viewed as complex adaptive systems consisting of many boundedly rational agents interacting through simple heterogeneous investment strategies, constantly adapting their behaviour in response

  2. Radiopharmaceutical scanning agents

    International Nuclear Information System (INIS)

    1976-01-01

    This invention is directed to dispersions useful in preparing radiopharmaceutical scanning agents, to technetium labelled dispersions, to methods for preparing such dispersions and to their use as scanning agents

  3. Reasoning about emotional agents

    NARCIS (Netherlands)

    Meyer, J.-J.

    In this paper we discuss the role of emotions in artificial agent design, and the use of logic in reasoning about the emotional or affective states an agent can reside in. We do so by extending the KARO framework for reasoning about rational agents appropriately. In particular we formalize in

  4. Asymptotically Optimal Agents

    OpenAIRE

    Lattimore, Tor; Hutter, Marcus

    2011-01-01

    Artificial general intelligence aims to create agents capable of learning to solve arbitrary interesting problems. We define two versions of asymptotic optimality and prove that no agent can satisfy the strong version while in some cases, depending on discounting, there does exist a non-computable weak asymptotically optimal agent.

  5. DEVELOPMENT OF ANTIVIRAL AGENTS

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. DEVELOPMENT OF ANTIVIRAL AGENTS. Chandipura virus can be regarded as a model system to design and develop antiviral agents. These agents could be small molecules or RNA/PNA aptamers or Antisense RNA to speicific gene sequence in the viral genome.

  6. Will the real Robert Neville please, come out? Vampirism, the ethics of queer monstrosity, and capitalism in Richard Matheson's I am legend?

    Science.gov (United States)

    Khader, Jamil

    2013-01-01

    In this article, I argue that Richard Matheson's (1954) vampire novella, I Am Legend, encodes the protagonist's, Robert Neville, traumatic recognition of his queer sexuality in its monstrosity (the unspeakability of male penetrability). Neville's identification with and desire for his undead neighbor, Ben Cortman, are symbolically codified through three different registers: intertextual references to vampiric conventions and codes, the semiotics of queer subculture, and a structure of doubling that links Neville to the queer vampire. Although Neville avoids encountering his unspeakable queer desire, which could be represented only at the level of the Lacanian Real, he must still confront Cortman's obsessive exhortations for him to come out. Only when he symbolically codifies his abnormality in its own monstrosity, by viewing himself through mutant vampires' eyes, can Neville reconfigure the ethical relationship between self and other, humans and mutant humans-vampires. However progressive Matheson's novella is in its advocacy of minority sexual rights, it still renders capitalism's problematic relationship with queer subjectivity invisible. Although capitalism overdetermines every aspect of the social field and makes Neville's daily life possible in its surplus enjoyment, the fundamental antagonism (class struggle) in capitalism is obscured by the assertion of identity politics.

  7. Radiographic scanning agent

    International Nuclear Information System (INIS)

    Bevan, J.A.

    1983-01-01

    This invention relates to radiodiagnostic agents and more particularly to a composition and method for preparing a highly effective technetium-99m-based bone scanning agent. One deficiency of x-ray examination is the inability of that technique to detect skeletal metastases in their incipient stages. It has been discovered that the methanehydroxydiphosphonate bone mineral-seeking agent is unique in that it provides the dual benefits of sharp radiographic imaging and excellent lesion detection when used with technetium-99m. This agent can also be used with technetium-99m for detecting soft tissue calcification in the manner of the inorganic phosphate radiodiagnostic agents

  8. Agente adaptable y aprendizaje

    Directory of Open Access Journals (Sweden)

    Arturo Angel Lara Rivero

    2013-05-01

    Full Text Available En este trabajo se contrasta el concepto de agente programado con el de agente complejo adaptable, se presenta una nueva visión ligada al aprendizaje y la estructura del agente. La imagen del agente se analiza considerando los modelos internos, la práctica, el concepto de rutina y la influencia en su comportamiento, y la importancia del aprendizaje ex ante y ex post. Por último se muestra que la resolución de problemas está sujeta a restricciones del agente y se describen las formas de explorar el espacio de soluciones mediante tres tipos de exploración: exhaustiva, aleatoria y selectiva.

  9. Agent Programming Languages and Logics in Agent-Based Simulation

    DEFF Research Database (Denmark)

    Larsen, John

    2018-01-01

    and social behavior, and work on verification. Agent-based simulation is an approach for simulation that also uses the notion of agents. Although agent programming languages and logics are much less used in agent-based simulation, there are successful examples with agents designed according to the BDI......Research in multi-agent systems has resulted in agent programming languages and logics that are used as a foundation for engineering multi-agent systems. Research includes reusable agent programming platforms for engineering agent systems with environments, agent behavior, communication protocols...... paradigm, and work that combines agent-based simulation platforms with agent programming platforms. This paper analyzes and evaluates benefits of using agent programming languages and logics for agent-based simulation. In particular, the paper considers the use of agent programming languages and logics...

  10. Moral actor, selfish agent.

    Science.gov (United States)

    Frimer, Jeremy A; Schaefer, Nicola K; Oakes, Harrison

    2014-05-01

    People are motivated to behave selfishly while appearing moral. This tension gives rise to 2 divergently motivated selves. The actor-the watched self-tends to be moral; the agent-the self as executor-tends to be selfish. Three studies present direct evidence of the actor's and agent's distinct motives. To recruit the self-as-actor, we asked people to rate the importance of various goals. To recruit the self-as-agent, we asked people to describe their goals verbally. In Study 1, actors claimed their goals were equally about helping the self and others (viz., moral); agents claimed their goals were primarily about helping the self (viz., selfish). This disparity was evident in both individualist and collectivist cultures, attesting to the universality of the selfish agent. Study 2 compared actors' and agents' motives to those of people role-playing highly prosocial or selfish exemplars. In content (Study 2a) and in the impressions they made on an outside observer (Study 2b), actors' motives were similar to those of the prosocial role-players, whereas agents' motives were similar to those of the selfish role-players. Study 3 accounted for the difference between the actor and agent: Participants claimed that their agent's motives were the more realistic and that their actor's motives were the more idealistic. The selfish agent/moral actor duality may account for why implicit and explicit measures of the same construct diverge, and why feeling watched brings out the better angels of human nature.

  11. Stabilized radiographic scanning agents

    International Nuclear Information System (INIS)

    Fawzi, M.B.

    1982-01-01

    Stable compositions useful as technetium 99m-based scintigraphic agents comprise gentisic acid or a pharmaceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (sup(99m)TcOsub(4)sup(-)) solution. The compositions are especially useful in combination with a phosphate or phosphonate material that carries the radionuclide to bone, thus providing a skeletal imaging agent

  12. Decontamination Data - Blister Agents

    Data.gov (United States)

    U.S. Environmental Protection Agency — Decontamination efficacy data for blister agents on various building materials using various decontamination solutions. This dataset is associated with the following...

  13. Empathic Agent Technology (EAT)

    NARCIS (Netherlands)

    Johnson, L.; van den Broek, Egon; Richards, D.; Sklar, E.; Wilensky, U.

    2005-01-01

    A new view on empathic agents is introduced, named: Empathic Agent Technology (EAT). It incorporates a speech analysis, which provides an indication for the amount of tension present in people. It is founded on an indirect physiological measure for the amount of experienced stress, defined as the

  14. Agents in domestic environments

    NARCIS (Netherlands)

    Daniël Telgen; John-Jules Meyer; Glenn Meerstra; Franc Pape; Ing. Erik Puik; Leo van Moergestel; Niels van Nieuwenburg; Wouter Langerak

    2013-01-01

    Athor supplied : "This paper describes an agent-based architecture for domotics. This architecture is based on requirements about expandability and hardware independence. The heart of the system is a multi-agent system. This system is distributed over several platforms to open the possibility to

  15. Change Agent Survival Guide

    Science.gov (United States)

    Dunbar, Folwell L.

    2011-01-01

    Consulting is a rough racket. Only a tarantula hair above IRS agents, meter maids and used car sales people, the profession is a prickly burr for slings and arrows. Throw in education, focus on dysfunctional schools and call oneself a "change agent," and this bad rap all but disappears. Unfortunately, though, consulting/coaching/mentoring in…

  16. Travel Agent Course Outline.

    Science.gov (United States)

    British Columbia Dept. of Education, Victoria.

    Written for college entry-level travel agent training courses, this course outline can also be used for inservice training programs offered by travel agencies. The outline provides information on the work of a travel agent and gives clear statements on what learners must be able to do by the end of their training. Material is divided into eight…

  17. Hyperthermia and chemotherapy agent

    International Nuclear Information System (INIS)

    Roizin-Towle, L.; Hall, E.J.

    1981-01-01

    The use of chemotherapeutic agents for the treatment of cancer dates back to the late 19th century, but the modern era of chemotherapy drugs was ushered in during the 1940's with the development of the polyfunctional alkylating agent. Since then, numerous classes of drugs have evolved and the combined use of antineoplastic agents with other treatment modalities such as radiation or heat, remains a large relatively unexplored area. This approach, combining local hyperthermia with chemotherapy agents affords a measure of targeting and selective toxicity not previously available for drugs. In this paper, the effects of adriamycin, bleomycin and cis-platinum are examined. The adjuvant use of heat may also reverse the resistance of hypoxic cells noted for some chemotherapy agents

  18. Los espantos de La sabana: leyendas y religiosidad de los Llanos venezolanos (The ghosts of Savannah: Legends and religion of the Venezuelan Ilanos - DOI: 10.5752/P.2175-5841.2013v11n30p572

    Directory of Open Access Journals (Sweden)

    Jenny González Muñoz

    2013-06-01

    Full Text Available Los procesos culturales de los pueblos rurales de América Latina en cuanto a su parte inmaterial, están íntimamente relacionados con la memoria colectiva y/o social, la cual puede fungir, entre otras cosas, para afianzar la transmisión de leyendas creadas por la sabiduría popular por medio de la tradición oral. En los llanos centro-occidentales venezolanos a lo largo de más dos siglos se ha diseminado cantidad de leyendas que cuentan la aparición de espíritus que vagan por las sabanas solitarias, sobre todo en las noches de mayor oscuridad; los llamados “espantos de la sabana” son las almas de antiguos pobladores, ya conocidos, que deambulan pidiendo oraciones para su descanso eterno, o por no poder encontrar la paz que procuran. Dichas narraciones, al pasar de generación en generación forman parte de la identidad llanera y son incluidas en la literatura nacional; en el presente artículo se destaca esta característica colocando como ejemplo la novela de Rómulo Gallegos, Cantaclaro, así como coplas populares o aquellas recopiladas por Alberto Arvelo Torrealba para establecer el enlace existente entre la creación y transmisión de las leyendas y la religiosidad de dicha cultura. Palabras clave: Espantos de la sabana. Leyendas populares. Llanos centro-occidentales venezolanos. Religiosidad. Abstract Cultural processes of rural populations in Latin America while its immaterial dimension, are closely related to social and collective memory, which can serve, among other thins, to strengthen the transmission of legends created by wisdom through oral tradition. In the plains of the Midwest Venezuelan, during more than two centuries, were heard many legends that tell the apparition of spirits which roam the savannas lonely, especially on the darkest nights. These "ghosts of Savannah" are the souls of old settlers who roam (roam because they can not find peace or because they are asking for prayers for his eternal rest. These stories

  19. Agent-Based Optimization

    CERN Document Server

    Jędrzejowicz, Piotr; Kacprzyk, Janusz

    2013-01-01

    This volume presents a collection of original research works by leading specialists focusing on novel and promising approaches in which the multi-agent system paradigm is used to support, enhance or replace traditional approaches to solving difficult optimization problems. The editors have invited several well-known specialists to present their solutions, tools, and models falling under the common denominator of the agent-based optimization. The book consists of eight chapters covering examples of application of the multi-agent paradigm and respective customized tools to solve  difficult optimization problems arising in different areas such as machine learning, scheduling, transportation and, more generally, distributed and cooperative problem solving.

  20. Agent Standards Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation of the work herein proposed is the development of standards for software autonomous agents. These standards are essential to achieve software...

  1. Health care agents

    Science.gov (United States)

    ... do not want these treatments. Order sterilization or abortion. Choosing Your Health Care Agent Choose a person ... working well. A health care proxy is a legal paper that you fill out. You can get ...

  2. Robust Agent-Based Systems Incorporating Teams of Communicating Agents

    National Research Council Canada - National Science Library

    Cohen, Philip

    2004-01-01

    ... (AgentTalk). The A3 architecture supports human participation as agents, dynamic formation of agent teams, reorganization of teams based on network loads, and offers libraries for legacy code to be able...

  3. Agent amplified communication

    Energy Technology Data Exchange (ETDEWEB)

    Kautz, H.; Selman, B.; Milewski, A. [AT& T Laboratories, Murray Hill, NJ (United States)

    1996-12-31

    We propose an agent-based framework for assisting and simplifying person-to-person communication for information gathering tasks. As an example, we focus on locating experts for any specified topic. In our approach, the informal person-to-person networks that exist within an organization are used to {open_quotes}referral chain{close_quotes} requests for expertise. User-agents help automate this process. The agents generate referrals by analyzing records of e-mail communication patterns. Simulation results show that the higher responsiveness of an agent-based system can be effectively traded for the higher accuracy of a completely manual approach. Furthermore, preliminary experience with a group of users on a prototype system has shown that useful automatic referrals can be found in practice. Our experience with actual users has also shown that privacy concerns are central to the successful deployment of personal agents: an advanced agent-based system will therefore need to reason about issues involving trust and authority.

  4. Monitoring volatile anaesthetic agents

    International Nuclear Information System (INIS)

    Russell, W.J.

    2000-01-01

    Full text: The methods that have been used for monitoring volatile anaesthetic agents depend on some physical property such as Density, Refractometry, Mass, Solubility, Raman scattering, or Infra-red absorption. Today, refractometry and infra-red techniques are the most common. Refractometry is used for the calibration of vaporizers. All anaesthetic agents increase the refractive index of the carrier gas. Provided the mixture is known then the refractive change measures the concentration of the volatile anaesthetic agent. Raman Scattering is when energy hits a molecule a very small fraction of the energy is absorbed and re-emitted at one or more lower frequencies. The shift in frequency is a function of the chemical bonds and is a fingerprint of the substance irradiated. Electromagnetic (Infra-red) has been the commonest method of detection of volatile agents. Most systems use a subtractive system, i.e. the agent in the sampling cell absorbed some of the infrared energy and the photo-detector therefore received less energy. A different approach is where the absorbed energy is converted into a pressure change and detected as sound (Acoustic monitor). This gives a more stable zero reference. More recently, the detector systems have used multiple narrow-band wavelengths in the infrared bands and by shape matching or matrix computing specific agent identification is achieved and the concentration calculated. In the early Datex AS3 monitors, a spectral sweep across the 3 micron infrared band was used to create spectral fingerprints. The recently released AS3 monitors use a different system with five very narrow band filters in the 8-10 micron region. The transmission through each of these filters is a value in a matrix which is solved by a micro computer to identify the agent and its concentration. These monitors can assist in improving the safety and efficiency of our anaesthetics but do not ensure that the patient is completely anaesthetized. Copyright (2000

  5. Nuclear maximarathon ... already a legend!

    International Nuclear Information System (INIS)

    Maisseu, Andre

    2001-01-01

    Since 1996, currently in May, the NucWorkers are running a 350 km length MaxiMarathon, somewhere in Europe. Those runners, ambassadors for their colleagues of nuclear industry, want remind to the public and to the decision makers the many advantages, for the environment protection, jobs creation and energetic independence of nuclear energy. The target of this event is the media, and, via the media, public opinion, a target that is hard to reach. The objective is very clear: to convert an event, which conveys a positive image of the nuclear industry, its workers, skills and job opportunities into a media success. Public opinion must realise that behind the design, building, operation and maintenance of all nuclear industry installations are men and women who take pride in their technical and industrial achievements, assume the responsibility for them, there are competent and serious women and men, and deserve to be trusted. The involvement in the job of regaining public sympathy is essential. Nuclear professionals are strong because they are the men and women who produce nuclear energy day to days, who build its success and who assume the risks. The credibility of nuclear professionals in the public eye is intact. This is why this involvement in the fight to win back public opinion is essential. For too long, nuclear industry professionals have failed to respond to the constant onslaught on their industry by the sensationalist media. This must change, but their reaction must be calm, peaceful yet forceful. The aim of the event, presenting nuclear people in a sporting context, with a strongly positive connotation, is to modify the negative image that the media too often give of the nuclear industry. This event should also demonstrate to the policy-makers that the NucWorkers represent a resource and a will with which they have to reckon, as it is the practice in every modern democracy. In 2001, over 1000 athletes, all of them nuclear industry workers, have arranged to meet to run from Smolensk to Moscow, relaying each other over the total distance of 350 km (215 miles). By undertaking this sporting endeavour the world's nuclear industry workers will be ambassadors bearing a message of peace and harmony, of technical progress shared by all, of the success of the nuclear power industry. The message is also a reminder of the multiple advantages of nuclear energy in terms of environmental protection, job creation, and the satisfaction of the world's energy requirements

  6. Carroll Cave: a Missouri legend

    Science.gov (United States)

    Carroll Cave is one of the premiere caves of Missouri and the Ozarks region. At over 20 miles of surveyed passage, it is the 2nd longest cave in the state and 33rd longest in the nation. It is also the largest known cave formed in the Ordovician aged (443-485 million years ago) Gasconade Dolomite o...

  7. Legend tummast abilisest / Elena Lass

    Index Scriptorium Estoniae

    Lass, Elena

    2003-01-01

    PÖFFi Suvekino raames näidati Tallinna Linnaarhiivi siseõues saksa tummfilmi programmi "Öised varjud". Paul Wegeneri ja Carl Boese 1920. a. valminud filmile "Golem, kuidas ta maailma tuli" tegid saatemuusikat Marianne Kõrver, Rainer Jancis ja Raoul Kurvitz

  8. Urban legends series: oral leukoplakia.

    Science.gov (United States)

    Arduino, P G; Bagan, J; El-Naggar, A K; Carrozzo, M

    2013-10-01

    To date, the term oral leukoplakia (OL) should be used to recognize 'predominantly white plaques of questionable risk, having excluded (other) known diseases or disorders that carry no increased risk of cancer'. In this review, we addressed four controversial topics regarding oral leukoplakias (OLs): (i) Do tobacco and alcohol cause OLs?, (ii) What percentage of OLs transform into oral squamous cell carcinoma (OSCC)?, (iii) Can we distinguish between premalignant and innocent OLs?, and (iv) Is proliferative verrucous leukoplakia (PVL) a specific entity or just a form of multifocal leukoplakia? Results of extensive literature search suggest that (i) no definitive evidence for direct causal relationship between smoked tobacco and alcohol as causative factors of OLs, (ii and iii) the vast majority of OLs follow a benign course and do not progress into a cancer, and no widely accepted and/or validated clinical and/or biological factors can predict malignant transformation, and (iv) the distinction between multifocal/multiple leukoplakias and PVL in their early presentation is impossible; the temporal clinical progression and the high rate of recurrences and development of cancer of PVL are the most reliable features for diagnosis. © 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. The Legend of Knidia Today

    Czech Academy of Sciences Publication Activity Database

    Bažant, Jan

    2017-01-01

    Roč. 53, č. 1/2 (2017), s. 77-110 ISSN 0046-1628 Institutional support: RVO:67985955 Keywords : Aphrodite * Knidia * Praxiteles * feminism Subject RIV: AB - History OBOR OECD: History ( history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  10. Teaching tourism change agents

    DEFF Research Database (Denmark)

    Blichfeldt, Bodil Stilling; Kvistgaard, Hans-Peter; Hird, John

    2017-01-01

    This article discuss es know ledge, competencies and skills Master’s students should obtain during their academic studies and particularly, the differences between teaching about a topic and teaching to do. This is ex emplified by experiential learning theory and the case of a change management...... course that is part of a Tourism Master’s program, where a major challenge is not only to teach students about change and change agents, but to teach them how change feels and ho w to become change agents. The c hange management course contains an experiment inspired by experiential teaching literature...... and methods. The experiment seeks to make students not only hear/learn about change agency and management, but to make them feel cha nge, hereby enabling them to develop the skills and competencies necessary for them to take on the role as change agent s and thus enable them to play key role s in implementing...

  11. Agents unleashed a public domain look at agent technology

    CERN Document Server

    Wayner, Peter

    1995-01-01

    Agents Unleashed: A Public Domain Look at Agent Technology covers details of building a secure agent realm. The book discusses the technology for creating seamlessly integrated networks that allow programs to move from machine to machine without leaving a trail of havoc; as well as the technical details of how an agent will move through the network, prove its identity, and execute its code without endangering the host. The text also describes the organization of the host's work processing an agent; error messages, bad agent expulsion, and errors in XLISP-agents; and the simulators of errors, f

  12. Developing Enculturated Agents

    DEFF Research Database (Denmark)

    Rehm, Matthias

    2010-01-01

    on our cultural profiles that provide us with heuristics of behavior and interpretation. Thus, integrating cultural aspects of communicative behaviors in virtual agents and thus enculturating such systems seems to be inevitable. But culture is a multi-defined domain and thus a number of pitfalls arise...... that have to be avoided in the endeavor. This chapter presents some of the pitfalls for enculturating interactive systems and presents strategies on how to avoid these pitfalls in relation to the standard development process of Embodied Conversational Agents....

  13. Teaching Tourism Change Agents

    DEFF Research Database (Denmark)

    Stilling Blichfeldt, Bodil; Kvistgaard, Hans-Peter; Hird, John

    2017-01-01

    This article discuss es know ledge, competencies and skills Master’s students should obtain during their academic studies and particularly, the differences between teaching about a topic and teaching to do. This is ex emplified by experiential learning theory and the case of a change management...... course that is part of a Tourism Master’s program, where a major challenge is not only to teach students about change and change agents, but to teach them how change feels and ho w to become change agents. The c hange management course contains an experiment inspired by experiential teaching literature...

  14. De la leyenda criminológica a la quimera criminológica …A través de la mitología penal… Ensayo observacional, experimental, situacional y prospectivo/From criminological legend to the criminological chimera …Through criminal mythology... Observational, experimental, situational and prospective trial

    Directory of Open Access Journals (Sweden)

    Gino Ríos Patio

    2015-08-01

    Full Text Available The essayist presents his personal view on the past, present and future of criminology and criminal law, using metaphors of legend, myth and illusion, as a system of popular beliefs about real phenomena that are intended to conceal the true purpose for which they are built and maintained, explaining and justifying the status quo through the history of peoples.

  15. Software Agent Techniques in Design

    DEFF Research Database (Denmark)

    Hartvig, Susanne C

    1998-01-01

    This paper briefly presents studies of software agent techniques and outline aspects of these which can be applied in design agents in integrated civil engineering design environments.......This paper briefly presents studies of software agent techniques and outline aspects of these which can be applied in design agents in integrated civil engineering design environments....

  16. Agent Persuasion Mechanism of Acquaintance

    Science.gov (United States)

    Jinghua, Wu; Wenguang, Lu; Hailiang, Meng

    Agent persuasion can improve negotiation efficiency in dynamic environment based on its initiative and autonomy, and etc., which is being affected much more by acquaintance. Classification of acquaintance on agent persuasion is illustrated, and the agent persuasion model of acquaintance is also illustrated. Then the concept of agent persuasion degree of acquaintance is given. Finally, relative interactive mechanism is elaborated.

  17. H.G. Stoker (1999–1993 as Christelike filosoof: ’n Historiese legende en ikoon, of nog steeds ’n kontemporêre mentor?

    Directory of Open Access Journals (Sweden)

    Barend J. van der Walt

    2013-03-01

    Full Text Available ’n Tradisie, wat ’n filosofiese tradisie insluit, kan alleen lewend bly as die verhaal daarvan aan die jonger geslag oorvertel word. Daarom bied hierdie inleidende en oorsigtelike artikel aan die leser iets oor die unieke filosofie van die Suid-Afrikaanse denker, Henk Stoker. Ter inleiding behandel dit die moontlike redes waarom sy denke in Suid-Afrika en elders vandag relatief onbekend is en minder invloedryk was in vergelyking met dié van die twee ander vaders van ’n reformatoriese filosofie, naamlik Dirk H.Th. Vollenhoven en veral Herman Dooyeweerd. Daarna word aandag geskenk aan die Suid-Afrikaanse milieu waarbinne sy filosofie gebore is. Die moontlike interne en eksterne teologiese en filosofiese invloede van veral Herman Bavinck (1854–1921 en Max Scheler (1874–1928 word behandel. Vervolgens word op enkele van Stoker se oorspronklikste bydraes tot die Christelik-filosofiese tradisie gewys. ’n Vlugtige blik word op die wedersydse kritiek tussen Stoker, Dooyeweerd en sekere leerlinge van Dooyeweerd gewerp. Ten slotte kan daar, in die lig van hierdie onderlinge verskille, sekere wanopvattings reggestel word, byvoorbeeld dat ’n Reformatoriese filosofie ’n statiese en geslote sisteem is. H.G. Stoker (1899–1993 as Christian philosopher: historical legend and icon, or still a contemporary mentor? Tradition which includes a philosophical tradition, can only been kept alive when its story is told to younger generations. This is the motivation behind this introductory overview of the unique philosophy of the South African philosopher, Henk Stoker. In comparison with the two other founders of a reformational philosophy, Dirk H.Th. Vollenhoven (1892–1978 and especially Herman Dooyeweerd (1994–1977, Stoker’s ideas are in South Africa, as well as abroad, less well-known among reformed people. The introductory part of this article, therefore, investigates the possible reasons for the relatively small impact of his thinking. The

  18. SECOND BUYING AGENT

    CERN Multimedia

    SPL - SERVICES ACHATS

    2000-01-01

    Last year the buying agent LOGITRADE started operations on the CERN site, processing purchasing requests for well-defined families of products up to a certain value. It was planned from the outset that a second buying agent would be brought in to handle the remaining product families. So, according to that plan, the company CHARLES KENDALL will be commencing operations at CERN on 8 May 2000 in Building 73, 1st floor, offices 31 and 35 (phone and fax numbers to be announced).Each buying agent will have its own specific list of product families and will handle purchasing requests up to 10'000 CHF.Whenever possible they will provide the requested supplies at a price (including the cost of their own services) which must be equivalent to or lower than the price mentioned on the purchasing request, changing the supplier if necessary. If a lower price cannot be obtained, agents will provide the necessary administrative support free of charge.To ensure that all orders are processed in the best possible conditions, us...

  19. Fluoroquinolone antimicrobial agents.

    OpenAIRE

    Wolfson, J S; Hooper, D C

    1989-01-01

    The fluoroquinolones, a new class of potent orally absorbed antimicrobial agents, are reviewed, considering structure, mechanisms of action and resistance, spectrum, variables affecting activity in vitro, pharmacokinetic properties, clinical efficacy, emergence of resistance, and tolerability. The primary bacterial target is the enzyme deoxyribonucleic acid gyrase. Bacterial resistance occurs by chromosomal mutations altering deoxyribonucleic acid gyrase and decreasing drug permeation. The dr...

  20. Socially Intelligent Tutor Agents

    NARCIS (Netherlands)

    Heylen, Dirk K.J.; Nijholt, Antinus; op den Akker, Hendrikus J.A.; Vissers, M.; Aylett, R.; Ballin, D.; Rist, T.

    2003-01-01

    Emotions and personality have received quite a lot of attention the last few years in research on embodied conversational agents. Attention is also increasingly being paid to matters of social psychology and interpersonal aspects, for work of our group). Given the nature of an embodied

  1. Cell control with agents

    NARCIS (Netherlands)

    Ir Peter Boots; Ir. Dick van Schenk Brill

    2000-01-01

    A software system is described that uses the agent concept in the Cell Control layer. Important design goals are: the system continues as good as possible after a process crash, crashed processes are recreated whenever possible, and equivalent workstations are allocated dynamically. This project is

  2. The need for agents

    DEFF Research Database (Denmark)

    Abolfazlian, Ali Reza Kian

    1996-01-01

    I denne artikel arbejder vi med begrebet Intelligent Software Agents (ISAs), som autonomous, social, reactive, proactive og subservient computer systemer. Baseret på socialt psykologiske argumenter viser jeg endvidere, hvordan både den menneskelige natur og det teknologiske stadium, som mennesket...

  3. Multimodal training between agents

    DEFF Research Database (Denmark)

    Rehm, Matthias

    2003-01-01

    In the system Locator1, agents are treated as individual and autonomous subjects that are able to adapt to heterogenous user groups. Applying multimodal information from their surroundings (visual and linguistic), they acquire the necessary concepts for a successful interaction. This approach has...

  4. Mevlana’nın Menkıbeleri Üzerine Folklorik Bir İnceleme A Folkloric Analysis on the Legends of Mevlana

    Directory of Open Access Journals (Sweden)

    Gülay KARAMAN

    2012-09-01

    Full Text Available behavior to be proud of. Its plural form menakıb for the first time in this meaning, is used in the corpus of hadith which had been written and compiled by IXth century to describe the virtues of prophet Muhammed and his companians. Furthermore, writings consist of the biography of historical personages, the description of works of worthies and even some of the holy cities are also called menakıb. While at the begining menakıbnames were created in order to describe high moral values of both the prophet Muhammed and his companians in later periods, the lives of some important men of sufism and religious orders were also added to this account. The first known example of Türkish menakıbname literature is Tezkire-i Satuk Buğra Han which is from Karahanlı period. Turkish menakıbname literature that begun with Tezkire-i Satuk Buğra Han, also continued to spread quickly among the Muslim Turks came to Anatolia and settled by migrations. Since the author is a member of his own society naturally his work will be a mirror to social, cultural, economical, political life of its century. For this reason, menakıbnames which tell the extraordinary life stories of saints are very important sources of information especially for history, culture, folklore and literature. After careful studies on the legends it can be possible to reach very rich source of information. In Türkiye, Fuad Köprülü is the first name with his work called as Türk Edebiyatında İlk Mutasavvıflar who pointed out using menakıbnames in scientific studies. In this study we want to call attention to Menâkıbu’l-Ârifîn which tells the legends of Mevlana and the other Mevlevi saints. Menâkıbu’l-Ârifîn is written by Mevlevi Ahmed Eflâkî in 14th century after the request of his sheik Ulu Arif Çelebi in Persian. This menakıbname has a certain place in Turkish history and culture since it gives first-hand information about Mevlana and the other Mevlevi saints. In this

  5. From Law to Urban Legend, and Vice Versa: Creative Food Counterfeiting in Early Modern Spain / De la ley a la leyenda urbana y viceversa: falsificaciones de la cocina creativa en la España del Siglo de Oro

    Directory of Open Access Journals (Sweden)

    Elena del Río Parra

    2012-04-01

    Full Text Available ABSTRACT. This text takes on common urban legends related to food forgery in order to find ground in legal texts. While literature is keen on food counterfeiting and perpetuates common to- pics, there seems to be more than a taste for lite- rary expression: town cries and ordinances are eloquent in pointing out elaborate methods to manipulate certain foods, some of which coincide to what were believed to be cultural myths. RESUMEN. Este texto se aproxima a conocidas leyendas urbanas relacionadas con la falsificación de alimentos para encontrar su base en textos legales. Si bien en la literatura son frecuentes las menciones a comida manipulada, estas parecen ser más que una repetición de lugares comunes: pregones y ordenanzas abundan en métodos muy elaborados de alteración de ciertos alimentos, algunos de los cuales coinciden con lo que hasta ahora entendíamos como mitos culturales.

  6. Towards Soft Computing Agents

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman; Krušina, Pavel; Petrová, Zuzana

    2000-01-01

    Roč. 10, č. 5 (2000), s. 859-868 ISSN 1210-0552. [SOFSEM 2000 Works hop on Soft Computing. Milovy, 27.11.2000-28.11.2000] R&D Projects: GA ČR GA201/00/1489; GA ČR GA201/99/P057 Institutional research plan: AV0Z1030915 Keywords : hybrid systems * intelligent agents Subject RIV: BA - General Mathematics

  7. Amphoteric surface active agents

    OpenAIRE

    Eissa, A.M. F.

    1995-01-01

    2-[trimethyl ammonium, triethyl ammonium, pyridinium and 2-amino pyridinium] alkanoates, four series of surface active agents containing carbon chain C12, C14, C16 and C18carbon atoms, were prepared. Their structures were characterized by microanalysis, infrared (IR) and nuclear magnetic resonance (NMR). Surface and interfacial tension, Krafft point, wetting time, emulsification power, foaming height a...

  8. Perioperative allergy: uncommon agents.

    Science.gov (United States)

    Caimmi, S; Caimmi, D; Cardinale, F; Indinnimeo, L; Crisafulli, G; Peroni, D G; Marseglia, G L

    2011-01-01

    Anesthesia may often be considered as a high-risk procedure and anaphylaxis remains a major cause of concern for anesthetists who routinely administer many potentially allergenic agents. Neuromuscular blocking agents, latex and antibiotics are the substances involved in most of the reported reactions. Besides these three agents, a wide variety of substances may cause an anaphylactic reaction during anesthesia. Basically all the administered drugs or substances may be potential causes of anaphylaxis. Among them, those reported the most in literature include hypnotics, opioids, local anesthetics, colloids, dye, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Iodinated Contrast Media (ICM), antiseptics, aprotinin, ethylene oxyde and formaldehyde, and protamine and heparins. No premedication can effectively prevent an allergic reaction and a systematic preoperative screening is not justified for all patients; nevertheless, an allergy specialist should evaluate those patients with a history of anesthesia-related allergy. Patients must be fully informed of investigation results, and advised to provide a detailed report prior to future anesthesia.

  9. Development of Targeted Therapeutic Agents for Botulism

    Science.gov (United States)

    2001-02-01

    remodelling’ at the 13th IST World Congress on Animal, Plant and Microbial Toxins. April, Costa Brava , Spain : Guest presenter on ’Nerve regeneration...incubated at 37°C in LISM for 24 h in the absence (open bars ) or presence (hatched bars ) of 6.6 nM BoNT/A (A) or 66 nM BoNT/B (B). After replacement of...in the absence (open bars ) or presence (hatched bars ) of 6.6 nM BoNT/A, as described in the legend to Figure 13. After a 24 h recovery period, the

  10. Constructing Secure Mobile Agent Systems Using the Agent Operating System

    NARCIS (Netherlands)

    van t Noordende, G.J.; Overeinder, B.J.; Timmer, R.J.; Brazier, F.M.; Tanenbaum, A.S.

    2009-01-01

    Designing a secure and reliable mobile agent system is a difficult task. The agent operating system (AOS) is a building block that simplifies this task. AOS provides common primitives required by most mobile agent middleware systems, such as primitives for secure communication, secure and

  11. Logics for Intelligent Agents and Multi-Agent Systems

    NARCIS (Netherlands)

    Meyer, John-Jules Charles

    2014-01-01

    This chapter presents the history of the application of logic in a quite popular paradigm in contemporary computer science and artificial intelligence, viz. the area of intelligent agents and multi-agent systems. In particular we discuss the logics that have been used to specify single agents, the

  12. Holonic multi-agent systems

    OpenAIRE

    Gerber, Christian; Siekmann, Jörg; Vierke, Gero

    1999-01-01

    A holonic multi-agent paradigm is proposed, where agents give up parts of their autonomy and merge into a super-agent"(a holon), that acts - when seen from the outside - just as a single agent again. We explore the spectrum of this new paradigm, ranging from definitorial issues over classification of possible application domains, an algebraic characterization of the merge operation, to implementational aspects: We propose algorithms for holon formation and on-line re-configuration. Based on s...

  13. Respiratory agents: irritant gases, riot control agents, incapacitants, and caustics.

    Science.gov (United States)

    Warden, Craig R

    2005-10-01

    There are many chemical respiratory agents suitable for use by terrorists. They are the oldest chemical agents used and have caused the most casualties throughout the 20th century. Many are available in large quantities for industrial use and are susceptible to potential sabotage. This paper will concentrate on respiratory agents that are readily available and have the potential to cause a large number of casualties and panic. These agents have a lower rate of lethality when compared to other chemical agents but could produce many casualties that may overwhelm the emergency medical system.

  14. Chemical warfare agents

    Directory of Open Access Journals (Sweden)

    Vijayaraghavan R

    2010-01-01

    Full Text Available Among the Weapons of Mass Destruction, chemical warfare (CW is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare. Chemical weapons are inexpensive and are relatively easy to produce, even by small terrorist groups, to create mass casualties with small quantities. The characteristics of various CW agents, general information relevant to current physical as well as medical protection methods, detection equipment available and decontamination techniques are discussed in this review article. A brief note on Chemical Weapons Convention is also provided.

  15. Toxorhynchites as biocontrol agents.

    Science.gov (United States)

    Focks, Dana A

    2007-01-01

    Toxorhynchites is an unusual and interesting genus of large, non-biting mosquitoes. In spite of their size, they are--like many species of mosquitoes--completely harmless to man. The larvae are predaceous on other mosquitoes and aquatic organisms that inhabit both natural and artificial containers. Because this habitat is the source of several medically important species of mosquitoes, there is warrant for evaluating the potential of Toxorhynchites as a biological control agent under various conditions. Toxorhynchites is not seen as a panacea for the control of all container-inhabiting mosquitoes. However, it has demonstrated practical potential in certain restricted but important situations.

  16. Product and Agent

    DEFF Research Database (Denmark)

    Montecino, Alex; Valero, Paola

    2015-01-01

    In this paper we will explore how the “mathematics teacher” becomes a subject and, at the same time, is subjected as part of diverse dispositive of power. We argue that the mathematics teacher becomes both a product and a social agent, which has been set, within current societies, from the ideas...... of globalization, social progress, and competitive logic. For our approximation, we use the concepts societies of control, dispositive, and discourses from a Foucault–Deleuze toolbox. Our purpose is to cast light on the social and cultural constitution of the ways of thinking about the mathematics teacher. Hence...

  17. Motivating agents in software tutorials

    NARCIS (Netherlands)

    van der Meij, Hans

    2013-01-01

    Pedagogical agents can provide important support for the user in human–computer interaction systems. This paper examines whether a supplementary, motivating agent in a print tutorial can enhance student motivation and learning in software training. The agent served the role of motivator, attending

  18. Holograms as Teaching Agents

    Science.gov (United States)

    Walker, Robin A.

    2013-02-01

    Hungarian physicist Dennis Gabor won the Pulitzer Prize for his 1947 introduction of basic holographic principles, but it was not until the invention of the laser in 1960 that research scientists, physicians, technologists and the general public began to seriously consider the interdisciplinary potentiality of holography. Questions around whether and when Three-Dimensional (3-D) images and systems would impact American entertainment and the arts would be answered before educators, instructional designers and students would discover how much Three-Dimensional Hologram Technology (3DHT) would affect teaching practices and learning environments. In the following International Symposium on Display Holograms (ISDH) poster presentation, the author features a traditional board game as well as a reflection hologram to illustrate conventional and evolving Three-Dimensional representations and technology for education. Using elements from the American children's toy Operation® (Hasbro, 2005) as well as a reflection hologram of a human brain (Ko, 1998), this poster design highlights the pedagogical effects of 3-D images, games and systems on learning science. As teaching agents, holograms can be considered substitutes for real objects, (human beings, organs, and animated characters) as well as agents (pedagogical, avatars, reflective) in various learning environments using many systems (direct, emergent, augmented reality) and electronic tools (cellphones, computers, tablets, television). In order to understand the particular importance of utilizing holography in school, clinical and public settings, the author identifies advantages and benefits of using 3-D images and technology as instructional tools.

  19. [New agents for hypercholesterolemia].

    Science.gov (United States)

    Pintó, Xavier; García Gómez, María Carmen

    2016-02-19

    An elevated proportion of high cardiovascular risk patients do not achieve the therapeutic c-LDL goals. This owes to physicians' inappropriate or insufficient use of cholesterol lowering medications or to patients' bad tolerance or therapeutic compliance. Another cause is an insufficient efficacy of current cholesterol lowering drugs including statins and ezetimibe. In addition, proprotein convertase subtilisin kexin type 9 inhibitors are a new cholesterol lowering medications showing safety and high efficacy to reduce c-LDL in numerous already performed or underway clinical trials, potentially allowing an optimal control of hypercholesterolemia in most patients. Agents inhibiting apolipoprotein B synthesis and microsomal transfer protein are also providing a new potential to decrease cholesterol in patients with severe hypercholesterolemia and in particular in homozygote familial hypercholesterolemia. Last, cholesteryl ester transfer protein inhibitors have shown powerful effects on c-HDL and c-LDL, although their efficacy in cardiovascular prevention and safety has not been demonstrated yet. We provide in this article an overview of the main characteristics of therapeutic agents for hypercholesterolemia, which have been recently approved or in an advanced research stage. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  20. Amphoteric surface active agents

    Directory of Open Access Journals (Sweden)

    Eissa, A.M. F.

    1995-10-01

    Full Text Available 2-[trimethyl ammonium, triethyl ammonium, pyridinium and 2-amino pyridinium] alkanoates, four series of surface active agents containing carbon chain C12, C14, C16 and C18carbon atoms, were prepared. Their structures were characterized by microanalysis, infrared (IR and nuclear magnetic resonance (NMR. Surface and interfacial tension, Krafft point, wetting time, emulsification power, foaming height and critical micelle concentration (cmc were determined and a comparative study was made between their chemical structure and surface active properties. Antimicrobial activity of these surfactants was also determined.

    Se prepararon cuatro series de agentes tensioactivos del tipo 2-[trimetil amonio, trietil amonio, piridinio y 2-amino piridinio] alcanoatos, que contienen cadenas carbonadas con C12, C14, C16 y C18 átomos de carbono.
    Se determinaron la tensión superficial e interfacial, el punto de Krafft, el tiempo humectante, el poder de emulsionamiento, la altura espumante y la concentración critica de miscela (cmc y se hizo un estudio comparativo entre la estructura química y sus propiedades tensioactivas. Se determinó también la actividad antimicrobiana de estos tensioactivos. Estas estructuras se caracterizaron por microanálisis, infrarrojo (IR y resonancia magnética nuclear (RMN.

  1. الأسطورة في بلاد الرافدين دراسة في الفكر الأسطوري الملحمي في الثقافة السومرية والاكدية Legend in Mesopotamia Study in the legendary epic of thought in the Sumerian and Akkadian culture

    Directory of Open Access Journals (Sweden)

    Mazin Muhammed Hussain مازن محمد حسين

    2016-12-01

    Full Text Available By the title of research "the legend in Mesopotamia " behooves us was the definition of two subjects, the first theme is the (legend and the second is (Mesopotamia The first represents the topic or the event, and the second represent the place where the legend was happened therefore urged the tab search in the following form: The research includes a prelude touched it to the meaning of legend, and the concept of myth, followed by two topics, first topic included two axes The second topic was talking to mythology Mesopotamian and we chose the models of these myths was titled look at the myths of Mesopotamia and of course we chose a model or two models of these myths for talking about because there is no enough capacity to address the all Mesopotamian mythology. Also, the search included a finale where we reviewed our conclusions to search with an index of margins and sources that have been used in it.

  2. Flexible, secure agent development framework

    Science.gov (United States)

    Goldsmith,; Steven, Y [Rochester, MN

    2009-04-07

    While an agent generator is generating an intelligent agent, it can also evaluate the data processing platform on which it is executing, in order to assess a risk factor associated with operation of the agent generator on the data processing platform. The agent generator can retrieve from a location external to the data processing platform an open site that is configurable by the user, and load the open site into an agent substrate, thereby creating a development agent with code development capabilities. While an intelligent agent is executing a functional program on a data processing platform, it can also evaluate the data processing platform to assess a risk factor associated with performing the data processing function on the data processing platform.

  3. Mushrooms as therapeutic agents

    Directory of Open Access Journals (Sweden)

    Sushila Rathee

    2012-04-01

    Full Text Available Mushrooms have been known for their nutritional and culinary values and used as medicines and tonics by humans for ages. In modern terms, they can be considered as functional foods which can provide health benefits beyond the traditional nutrients. There are monographs that cover the medicinal and healing properties of some individual traditional mushrooms. There has been a recent upsurge of interest in mushrooms not only as a health food which is rich in protein but also as a source of biologically active compounds of medicinal value which include complementary medicine/dietary supplements for anticancer, antiviral, hepatoprotective, immunopotentiating and hypocholesterolemic agents. However the mechanisms of the various health benefits of mushrooms to humans still require intensive investigation, especially given the emergence of new evidence of their health benefits. In the present paper the medicinal potential of mushrooms is being discussed.

  4. Microencapsulation of chemotherapeutic agents

    International Nuclear Information System (INIS)

    Byun, Hong Sik

    1993-01-01

    Mixing various amounts of chemotherapeutic agents such as cisplatinum, 5-fluorouracil, mitomycin-C, and adriamycin with polymers such as poly-d, 1-lactide, ethylhydroxyethylcellulose, and polycaprolactone, several kinds of microcapsules were made. Among them, microcapsule made from ethylhydroxyethylcellulose showed best yield. Under light microscopy, the capsules were observed as particles with refractive properties. For the basic toxicity test, intraarterial administration of cisplatinum was done in 6 adult mongrel dogs. Follow-up angiography was accomplished in 2 wk intervals for 6 wks. Despite no significant difference in the histopathological examination between the embolized and normal kidneys, follow-up angiogram showed atrophy of renal cortex and diminished numbers of arterial branches in the embolized kidneys. In order to identify the structural properties of microcapsules, and to determine the drug content and the rate of release, further experiment is thought to be necessary. (Author)

  5. New MR contrast agent

    International Nuclear Information System (INIS)

    Grossman, C.D.; Subramanian, G.; Schneider, R.; Szeverenyi, N.E.; Rosenbaum, A.M.; Gagne, G.; Tillapaugh-Fay, G.; Berlin, R.; Ritter-Hrncirik, C.; Yu, S.

    1990-01-01

    This paper evaluates an MR contrast agent-meglumine tris-(2,6-dicarboxypyridine) gadolinium (III) or gadolinium dipicolinate (Gd-DPC)-produced in-house. Rats were anesthetized with pentobarbital. For renal imaging, bowel motion artifact was minimized with glucagon (0.014 mg/kg, intravenous (IV)). Enhanced images were generated on a 2-T chemical shift imaging system with a 31-cm horizontal bore magnet after IV injection of Gd-DPC (100 μM/kg). Coronal sections of the kidneys and sagittal sections of the brain, 2 mm thick, were made. Six to eight excitations and 128 or 356 phase-encoding steps were used for each image. Control animals were injected with equivalent doses of gadopentetate dimeglumine

  6. A Composite Agent Architecture for Multi-Agent Simulations

    OpenAIRE

    VanPutte, Michael; Osborn, Brian; Hiles, John

    2002-01-01

    CGF Computer Generated Forces and Behavioral Representation The MOVES Institute’s Computer-Generated Autonomy Group has focused on a research goal of modeling complex and adaptive behavior while at the same time making the behavior easier to create and control. This research has led to several techniques for agent construction, that includes a social and organization relationship management engine, a composite agent architecture, an agent goal apparatus, a structure for capturi...

  7. Odor Classification using Agent Technology

    Directory of Open Access Journals (Sweden)

    Sigeru OMATU

    2014-03-01

    Full Text Available In order to measure and classify odors, Quartz Crystal Microbalance (QCM can be used. In the present study, seven QCM sensors and three different odors are used. The system has been developed as a virtual organization of agents using an agent platform called PANGEA (Platform for Automatic coNstruction of orGanizations of intElligent Agents. This is a platform for developing open multi-agent systems, specifically those including organizational aspects. The main reason for the use of agents is the scalability of the platform, i.e. the way in which it models the services. The system models functionalities as services inside the agents, or as Service Oriented Approach (SOA architecture compliant services using Web Services. This way the adaptation of the odor classification systems with new algorithms, tools and classification techniques is allowed.

  8. Agent-based enterprise integration

    Energy Technology Data Exchange (ETDEWEB)

    N. M. Berry; C. M. Pancerella

    1998-12-01

    The authors are developing and deploying software agents in an enterprise information architecture such that the agents manage enterprise resources and facilitate user interaction with these resources. The enterprise agents are built on top of a robust software architecture for data exchange and tool integration across heterogeneous hardware and software. The resulting distributed multi-agent system serves as a method of enhancing enterprises in the following ways: providing users with knowledge about enterprise resources and applications; accessing the dynamically changing enterprise; locating enterprise applications and services; and improving search capabilities for applications and data. Furthermore, agents can access non-agents (i.e., databases and tools) through the enterprise framework. The ultimate target of the effort is the user; they are attempting to increase user productivity in the enterprise. This paper describes their design and early implementation and discusses the planned future work.

  9. Radioactive scanning agents with stabilizer

    International Nuclear Information System (INIS)

    Fawzi, M.B.

    1982-01-01

    Stable compositions useful as technetium 99-based scintigraphic agents comprise gentisyl alcohol or a pharmaceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (sup(99m)TcOsub(4)sup(-)) solution. The compositions are especially useful in combination with a phosphate or phosphonate material that carries the radionuclide to bone, thus providing a skeletal imaging agent

  10. Believable Social and Emotional Agents.

    Science.gov (United States)

    1996-05-01

    generation). Our agent is now also capable of talking about its emo- tions. Emotions might also affect how the agent speaks, such as stuttering when the...he will eventually tell the teacher and get the user in trouble1. Sluggo goes into the trade with an impatient and aggressive attitude and quickly...personality resulted in a more interesting character. 1. There is no teacher agent in the simulation, but the simulation can end with a message to the user

  11. Towards Information-Seeking Agents

    OpenAIRE

    Bachman, Philip; Sordoni, Alessandro; Trischler, Adam

    2016-01-01

    We develop a general problem setting for training and testing the ability of agents to gather information efficiently. Specifically, we present a collection of tasks in which success requires searching through a partially-observed environment, for fragments of information which can be pieced together to accomplish various goals. We combine deep architectures with techniques from reinforcement learning to develop agents that solve our tasks. We shape the behavior of these agents by combining e...

  12. Choice a real estate agent

    OpenAIRE

    Pantelic, Marija

    2014-01-01

    Every year a hundreds of new Estate agents is examined, and new agency comes to, which increase the competition for estate agents. Property sellers have the option to choose the estate agent which they think is the best one that will best mediate their property at a flexible and a correct way. It has been common that property sellers choose and compare estate agents in the city, the competition is today equal outside the city as in the city. Possibly, these are other criteria that values high...

  13. Judicial supervision of enforcement agents

    Directory of Open Access Journals (Sweden)

    Bodiroga Nikola

    2015-01-01

    Full Text Available The main focus of this paper is the supervision of enforcement agents conducted by enforcement courts. Law on Enforcement and Security recognizes three levels of control of enforcement agents. Certain monitoring powers are delegated to the Ministry of Justice and to Chamber of Enforcement Agents. However, for parties and other participants to enforcement proceedings control of enforcement agents implemented by enforcement courts seems to be the most important one. The strongest powers of enforcement agents are related to the special procedure for collection of claims for utilities and other similar services (exclusive competence of enforcement agents and for carrying out the enforcement (if enforcement creditor has requested it. When it comes to special procedure for collection of claims for utilities and other similar services objection can be used in order to control legality of decisions rendered by enforcements agents. However, many procedural issues related to the objection procedure remain unsolved. Motion for correction of irregularities is the only legal remedy that can be used when enforcement is being carried out by enforcement agents. This legal remedy cannot be considered an effective one in the sense of Article 13 European Convention for Protection of Human Rights and Fundamental Liberties. The new proposed Law on Enforcement and Security expected to come into force on July 1, 2016, will delegate the exclusive competence for carrying out the enforcement to enforcement agents (except cases related to family relations and reinstatement, but it will not improve the court supervision of their work.

  14. GOAL Agents Instantiate Intention Logic

    OpenAIRE

    Hindriks, Koen; van der Hoek, Wiebe

    2008-01-01

    It is commonly believed there is a big gap between agent logics and computational agent frameworks. In this paper, we show that this gap is not as big as believed by showing that GOAL agents instantiate Intention Logic of Cohen and Levesque. That is, we show that GOAL agent programs can be formally related to Intention Logic.We do so by proving that the GOAL Verification Logic can be embedded into Intention Logic. It follows that (a fragment of) Intention Logic can be used t...

  15. Business Intelligence using Software Agents

    Directory of Open Access Journals (Sweden)

    Ana-Ramona BOLOGA

    2011-12-01

    Full Text Available This paper presents some ideas about business intelligence today and the importance of developing real time business solutions. The authors make an exploration of links between business intelligence and artificial intelligence and focuses specifically on the implementation of software agents-based systems in business intelligence. There are briefly presented some of the few solutions proposed so far that use software agents properties for the benefit of business intelligence. The authors then propose some basic ideas for developing real-time agent-based software system for business intelligence in supply chain management, using Case Base Reasoning Agents.

  16. Stable agents for imaging investigations

    International Nuclear Information System (INIS)

    Tofe, A.J.

    1976-01-01

    This invention concerns highly stable compounds useful in preparing technetium 99m based scintiscanning exploration agents. The compounds of this invention include a pertechnetate reducing agent or a solution of oxidized pertechnetate and an efficient proportion, sufficient to stabilize the compounds in the presence of oxygen and of radiolysis products, of ascorbic acid or a pharmaceutically acceptable salt or ester of this acid. The invention also concerns a perfected process for preparing a technetium based exploration agent, consisting in codissolving the ascorbic acid or a pharmaceutically acceptable salt or ester of such an acid and a pertechnetate reducing agent in a solution of oxidized pertechnetate [fr

  17. Gastrointestinal scanning agent

    International Nuclear Information System (INIS)

    Francis, M.D.

    1980-01-01

    An easily prepared radiolabeled gastrointestinal scanning agent is described. Technetium-99m has ideal characteristics for imaging the upper and lower GI tract and determining stomach emptying and intestinal transit time when used with an insoluble particulate material. For example, crystalline and amorphous calcium phosphate particles can be effectively labeled in a one-step process using sup(99m)TcO 4 and SnCl 2 . These labeled particles have insignificant mass and when administered orally pass through the GI tract unchanged, without affecting the handling and density of the intestinal contents. Visualization of the esophageal entry into the stomach, the greater and lesser curvatures of the stomach, ejection into the duodenum, and rates of passage through the upper and lower GI tract are obtained. The slurry of sup(99m)TC particulate can be given rectally by enema. Good images of the cecum and the ascending, transverse, and descending colon are obtained. Mucosal folds and the splenic and hepatic flexures are visualized. The resilience of the large intestine is also readily visualized by pneumocolonographic techniques. (author)

  18. Incorporating BDI Agents into Human-Agent Decision Making Research

    Science.gov (United States)

    Kamphorst, Bart; van Wissen, Arlette; Dignum, Virginia

    Artificial agents, people, institutes and societies all have the ability to make decisions. Decision making as a research area therefore involves a broad spectrum of sciences, ranging from Artificial Intelligence to economics to psychology. The Colored Trails (CT) framework is designed to aid researchers in all fields in examining decision making processes. It is developed both to study interaction between multiple actors (humans or software agents) in a dynamic environment, and to study and model the decision making of these actors. However, agents in the current implementation of CT lack the explanatory power to help understand the reasoning processes involved in decision making. The BDI paradigm that has been proposed in the agent research area to describe rational agents, enables the specification of agents that reason in abstract concepts such as beliefs, goals, plans and events. In this paper, we present CTAPL: an extension to CT that allows BDI software agents that are written in the practical agent programming language 2APL to reason about and interact with a CT environment.

  19. The Agent of Change: The Agent of Conflict.

    Science.gov (United States)

    Hatfield, C. R., Jr.

    This speech examines the role of change agents in third world societies and indicates that the change agent must, to some extent, manipulate the social situation, even if his view of society is a more optimistic one than he finds in reality. If he considers strains and stresses to be the lubricants of change, then his focus on conflict as a…

  20. TACtic- A Multi Behavioral Agent for Trading Agent Competition

    Science.gov (United States)

    Khosravi, Hassan; Shiri, Mohammad E.; Khosravi, Hamid; Iranmanesh, Ehsan; Davoodi, Alireza

    Software agents are increasingly being used to represent humans in online auctions. Such agents have the advantages of being able to systematically monitor a wide variety of auctions and then make rapid decisions about what bids to place in what auctions. They can do this continuously and repetitively without losing concentration. To provide a means of evaluating and comparing (benchmarking) research methods in this area the trading agent competition (TAC) was established. This paper describes the design, of TACtic. Our agent uses multi behavioral techniques at the heart of its decision making to make bidding decisions in the face of uncertainty, to make predictions about the likely outcomes of auctions, and to alter the agent's bidding strategy in response to the prevailing market conditions.

  1. Players' agents worldwide: legal aspects

    NARCIS (Netherlands)

    Siekmann, R.C.R.; Parrish, R.; Branco Martins, R.; Soek, J.W.

    2007-01-01

    Publicly, at least, there appears to be a strong collective will within football to clean up the game, to make the work of players’ agents more transparent and to allow a greater share of the game’s profits to stay within the game. Privately, there seems to be unease that current agent regulation is

  2. Overview of shoreline cleaning agents

    International Nuclear Information System (INIS)

    Clayton, J.

    1992-01-01

    Chemical cleaning agents may be used to promote release of stranded oil from shorelines for reasons including biological sensitivity of indigenous fauna and flora to the oil, amenity considerations of the shoreline, or concern about refloating of the oil and subsequent stranding on adjacent shorelines. While use of chemical cleaning agents may be appropriate under proper toxic responses in circumstances, certain limitations should be recognized. The potential for toxic responses in indigenous fauna and flora to the cleaning agents must be considered. Enhanced penetration of oil into permeable shorelines following treatment with chemical cleaning agents also is not desirable. However, if conditions related to toxicity and substrate permeability are determined to be acceptable, the use of chemical cleaning agents for treatment of stranded oil can be considered. Chemical agents for cleaning oiled shorelines can be grouped into three categories: (1) non-surfactant-based solvents, (2) chemical dispersants, and (3) formulations especially designed to release stranded oil from shoreline substrates (i.e., shoreline-cleaning-agents). Depending on the specific circumstances present on an oiled shoreline, it is generally desirable that chemical agents used for cleaning will release oil from shoreline substrate(s) to surface waters. Recovery of the oil can then be accomplished by mechanical procedures such as booming and skimming operations

  3. Dialogue Games for Agent Argumentation

    Science.gov (United States)

    McBurney, Peter; Parsons, Simon

    The rise of the Internet and the growth of distributed computing have led to a major paradigm shift in software engineering and computer science. Until recently, the notion of computation has been variously construed as numerical calculation, as information processing, or as intelligent symbol analysis, but increasingly, it is now viewed as distributed cognition and interaction between intelligent entities [60]. This new view has major implications for the conceptualization, design, engineering and control of software systems, most profoundly expressed in the concept of systems of intelligent software agents, or multi-agent systems [99]. Agents are software entities with control over their own execution; the design of such agents, and of multi-agent systems of them, presents major research and software engineering challenges to computer scientists.

  4. A Verification Logic for GOAL Agents

    Science.gov (United States)

    Hindriks, K. V.

    Although there has been a growing body of literature on verification of agents programs, it has been difficult to design a verification logic for agent programs that fully characterizes such programs and to connect agent programs to agent theory. The challenge is to define an agent programming language that defines a computational framework but also allows for a logical characterization useful for verification. The agent programming language GOAL has been originally designed to connect agent programming to agent theory and we present additional results here that GOAL agents can be fully represented by a logical theory. GOAL agents can thus be said to execute the corresponding logical theory.

  5. New agents for cancer chemoprevention.

    Science.gov (United States)

    Kelloff, G J; Boone, C W; Crowell, J A; Steele, V E; Lubet, R A; Doody, L A; Malone, W F; Hawk, E T; Sigman, C C

    1996-01-01

    Clinical chemoprevention trials of more than 30 agents and agent combinations are now in progress or being planned. The most advanced agents are well known and are in large Phase III chemoprevention intervention trials or epidemiological studies. These drugs include several retinoids [e.g., retinol, retinyl palmitate, all-trans-retinoic acid, and 13-cis-retinoic acid], calcium, Beta carotene, vitamin E, tamoxifen, and finasteride. Other newer agents are currently being evaluated in or being considered for Phase II and early Phase III chemoprevention trials. Prominent in this group are all-trans-N-(4-hydroxy phenyl)retinamide (4-HPR) (alone and in combination with tamoxifen), 2-difluoromethylornithine (DFMO), nonsteroidal antiinflammatory drugs (aspirin, piroxicam, sulindac), oltipraz, and dehydroepiandrostenedione (DHEA). A third group is new agents showing chemopreventive activity in animal models, epidemiological studies, or in pilot clinical intervention studies. They are now in preclinical toxicology testing or Phase I safety and pharmacokinetics trials preparatory to chemoprevention efficacy trials. These agents include S-allyl-l-cysteine, curcumin, DHEA analog 8354 (fluasterone), genistein, ibuprofen, indole-3-carbinol, perillyl alcohol, phenethyl isothiocyanate, 9-cis-retinoic acid, sulindac sulfone, tea extracts, ursodiol, vitamin D analogs, and p-xylyl selenocyanate. A new generation of agents and agent combinations will soon enter clinical chemoprevention studies based primarily on promising chemopreventive activity in animal models and in mechanistic studies. Among these agents are more efficacious analogs of known chemopreventive drugs including novel carotenoids (e.g., alpha-carotene and lutein). Also included are safer analogs which retain the chemopreventive efficacy of the parent drug such as vitamin D3 analogs. Other agents of high interest are aromatase inhibitors (e.g., (+)-vorozole), and protease inhibitors (e.g., Bowman-Birk soybean trypsin

  6. Smart Agents and Sentiment in the Heterogeneous Agent Model

    Czech Academy of Sciences Publication Activity Database

    Vácha, Lukáš; Baruník, Jozef; Vošvrda, Miloslav

    2009-01-01

    Roč. 18, č. 3 (2009), s. 209-219 ISSN 1210-0455 R&D Projects: GA MŠk(CZ) LC06075; GA ČR GP402/08/P207; GA ČR(CZ) GA402/09/0965 Institutional research plan: CEZ:AV0Z10750506 Keywords : heterogeneous agent model * market structure * smart traders * Hurst exponent Subject RIV: AH - Economics http://library.utia.cas.cz/separaty/2009/E/vacha- smart agents and sentiment in the heterogeneous agent model.pdf

  7. „…jistý kněz jménem Učen“. Komunikační role významotvorných jmen ve středověkých legendách na příkladu budečského kněze Učena – interpretační sonda

    Czech Academy of Sciences Publication Activity Database

    Večeře, Vojtěch

    2017-01-01

    Roč. 37, č. 1 (2017), s. 1-5 Institutional support: RVO:67985963 Keywords : Učen * legend * st. Wencelas * Budeč * archetype * ideal * educated Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  8. Immunological effects of hypomethylating agents.

    Science.gov (United States)

    Lindblad, Katherine E; Goswami, Meghali; Hourigan, Christopher S; Oetjen, Karolyn A

    2017-08-01

    Epigenetic changes resulting from aberrant methylation patterns are a recurrent observation in hematologic malignancies. Hypomethylating agents have a well-established role in the management of patients with high-risk myelodysplastic syndrome or acute myeloid leukemia. In addition to the direct effects of hypomethylating agents on cancer cells, there are several lines of evidence indicating a role for immune-mediated anti-tumor benefits from hypomethylating therapy. Areas covered: We reviewed the clinical and basic science literature for the effects of hypomethylating agents, including the most commonly utilized therapeutics azacitidine and decitabine, on immune cell subsets. We summarized the effects of hypomethylating agents on the frequency and function of natural killer cells, T cells, and dendritic cells. In particular, we highlight the effects of hypomethylating agents on expression of immune checkpoint inhibitors, leukemia-associated antigens, and endogenous retroviral elements. Expert commentary: In vitro and ex vivo studies indicate mixed effects on the function of natural killer, dendritic cells and T cells following treatment with hypomethylating agents. Clinical correlates of immune function have suggested that hypomethylating agents have immunomodulatory functions with the potential to synergize with immune checkpoint therapy for the treatment of hematologic malignancy, and has become an active area of clinical research.

  9. Complex responses to alkylating agents

    International Nuclear Information System (INIS)

    Samson, L.D.

    2003-01-01

    Using Affymetrix oligonucleotide GeneChip analysis, we previously found that, upon exposure to the simple alkylating agent methylmethane sulfonate, the transcript levels for about one third of the Saccharomyces cerevisiae genome (∼2,000 transcripts) are induced or repressed during the first hour or two after exposure. In order to determine whether the responsiveness of these genes has any relevance to the protection of cells against alkylating agents we have undertaken several follow-up studies. First, we explored the specificity of this global transcriptional response to MMS by measuring the global response of S. cerevisiae to a broad range of agents that are known to induce DNA damage. We found that each agent produced a very different mRNA transcript profile, even though the exposure doses produced similar levels of toxicity. We also found that the selection of genes that respond to MMS is highly dependent upon what cell cycle phase the cells are in at the time of exposure. Computational clustering analysis of the dataset derived from a large number of exposures identified several promoter motifs that are likely to control some of the regulons that comprise this large set of genes that are responsive to DNA damaging agents. However, it should be noted that these agents damage cellular components other than DNA, and that the responsiveness of each gene need not be in response to DNA damage per se. We have also begun to study the response of other organisms to alkylating agents, and these include E. coli, cultured mouse and human cells, and mice. Finally, we have developed a high throughput phenotypic screening method to interrogate the role of all non-essential S. cerevisiae genes (about 4,800) in protecting S. cerevisiae against the deleterious effects of alkylating agents; we have termed this analysis 'genomic phenotyping'. This study has uncovered a plethora of new pathways that play a role in the recovery of eukaryotic cells after exposure to toxic

  10. Industrial Agents: Emerging Applications of Software Agents in Industry

    OpenAIRE

    Leitão P.; Leitão, Paulo; Karnouskos, Stamatis

    2015-01-01

    The objective of this book is to address both industry practitioners and academia, providing the vision, on-going efforts, example applications, assessments, and roadmaps associated with industrial agents used in multiple industries. Such a book provides an introduction to the “industrial agents” domain by discussing up-to-date examples of their applications in industry, and it offers a view of future challenges with an accompanying roadmap. Part I introduces industrial agents,...

  11. Farmer to Pharmacist: Curcumin as an Anti-invasive and Antimetastatic Agent for the Treatment of Cancer

    Science.gov (United States)

    Bandyopadhyay, Debasish

    2014-12-01

    A huge number of compounds are widely distributed in nature and many of these possess medicinal/biological/pharmacological activity. Curcumin, a polyphenol derived from the rhizomes (underground stems) of Curcuma longa Linn (a member of the ginger family, commonly known as turmeric) is a culinary spice and therapeutic used in India for thousands of years to induce color and flavor in food as well as to treat a wide array of diseases. The origin of turmeric as spice and folklore medicine is so old that it is lost in legend. Curcumin has many beneficial pharmacological effects which includes, but are not limited with, antimicrobial, anti-inflammatory, antioxidant, antiviral, antiangiogenic, and antidiabetic activities. Most importantly curcumin possesses immense antitumorigenic effect. It prevents tumor invasion and metastasis in a number of animal models, including models of lung, liver, stomach, colon, breast, esophageal cancer etc. Invasion and metastasis are considered as one of the hallmarks in cancer biology. The pertinent recent applications of curcumin as anti-invasive and antimetastatic agent in in vitro and in vivo and ex vivo studies as well as associated molecular mechanisms have been discussed in this review. Curcumin has also demonstrated the ability to improve patient outcomes in clinical trials.

  12. Nuclear magnetic resonance contrast agents

    Science.gov (United States)

    Smith, P.H.; Brainard, J.R.; Jarvinen, G.D.; Ryan, R.R.

    1997-12-30

    A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC{sub 16}H{sub 14}N{sub 6}. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques. 10 figs.

  13. Cytotoxicity of dentin bonding agents.

    Science.gov (United States)

    Cal, Ebru; Guneri, Pelin; Atay, Ayse; Cetintas, Vildan Bozok

    2014-01-01

    This study sought to evaluate the cytotoxicity of 5 dentin bonding agents (Admira Bond, Adper Single Bond Plus, Clearfil SE Bond, Clearfil S3 Bond, and Heliobond) by XTT assay using human gingival fibroblast cells. Samples of dentin bonding agents were prepared on a black 96-well microplate, and the cytotoxicity of each bonding material was measured every 24 hours for 7 days, then on Days 14, 21, and 28. One-way ANOVA and Bonferroni post hoc tests were used for statistical analyses. All 5 materials were evaluated as severely cytotoxic (P agents showed severe cytotoxicity with viability results exception of Adper Single Bond Plus, toxicity continued to Day 28 for all compounds. The utmost care must be considered during the clinical utilization of dentin bonding agents to keep them within the area of restoration and prevent their contact with adjacent tissues.

  14. Chemical Agents: Facts about Evacuation

    Science.gov (United States)

    ... What CDC is Doing Blog: Public Health Matters Chemical Agents: Facts About Evacuation Format: Select one PDF [ ... on Facebook Tweet Share Compartir Some kinds of chemical accidents or attacks, such as a train derailment ...

  15. Relational agents: A critical review

    DEFF Research Database (Denmark)

    Campbell, Robert H.; Grimshaw, Mark Nicholas; Green, Gill

    2009-01-01

    Relationships between people who meet in virtual worlds are common and these relationships can be long term, in some cases lasting a life-time. Although relationships formed in virtual worlds have invited a lot of recent interest, surprisingly little work has been done on developing computer agen...... but remain few and far between. This review critically assesses the progress of relational agent development and research since their inception in 2005, proposes new areas of research and considers the potential for their exploitation in virtual worlds....... and non-player characters that can actively participate in such relationships. The focus of this review is relational agents, agents that can build long term socioemotional relationships with users. In virtual worlds, such agents are just starting to emerge; they are more common in other environments...

  16. Antisense Treatments for Biothreat Agents

    National Research Council Canada - National Science Library

    Warfield, Kelly L; Panchal, Rekha G; Aman, M J; Bavari, Sina

    2006-01-01

    ... a variety of pathogens in cell culture studies and nonhuman primate models of infection. For these reasons, antisense technologies are being pursued as treatments against biothreat agents such as Ebola virus, dengue virus and Bacillus anthracis...

  17. Business Intelligence using Software Agents

    OpenAIRE

    Ana-Ramona BOLOGA; Razvan BOLOGA

    2011-01-01

    This paper presents some ideas about business intelligence today and the importance of developing real time business solutions. The authors make an exploration of links between business intelligence and artificial intelligence and focuses specifically on the implementation of software agents-based systems in business intelligence. There are briefly presented some of the few solutions proposed so far that use software agents properties for the benefit of business intelligence. The authors then...

  18. Mobile Objects and Agents (MOA)

    Science.gov (United States)

    Milojicic, Dejan S.; LaForge, William; Chauhan, Deepika

    1998-12-01

    This paper describes the design and implementation of the Mobile Objects and Agents (MOA) project at the Open Group Research Institute. MOA was designed to support migration, communication and control of agents. It was implemented on top of the Java Virtual Machine, without any modifications to it. The initial project goals were to support communication across agent migration, as a means for collaborative work; and to provide extensive resource control, as a basic support for countering denial of service attacks. In the course of the project we added two further goals: compliance with the Java Beans component model, which provides for additional configurability and customization of agent system and agent applications; and interoperability, which allows cooperation with other agent systems. This paper analyses the architecture of MOA, in particular the support for mobility, naming and locating, communication, and resource management. Object and component models of MOA are discussed and some implementation details described. We summarize the lessons learned while developing and implementing MOA and compare it with related work.

  19. Oral hypoglycemic agents in pregnancy.

    Science.gov (United States)

    Tran, Nam D; Hunter, Stephen K; Yankowitz, Jerome

    2004-06-01

    Pregnancies in diabetic women are associated with increased risk of spontaneous abortion, congenital malformations, preeclampsia, preterm labor, macrosomia, shoulder dystocia, and cesarean section. Advances in antepartum cares and strict adherence to dietary and insulin regimens have been shown to significantly reduce the rate of maternal morbidity as well as perinatal morbidity and mortality. Historically, reports of potential fetal teratogenicity and hypoglycemic effects on the fetus contraindicated the use of oral hypoglycemic agents in pregnancies complicated with either type II diabetes mellitus (DM) or gestational diabetes mellitus (GDM). Recently, physicians increasingly prescribe newer generations of oral hypoglycemic agents to treat GDM and type II DM to pregnant patients. This review addresses the safety, current recommendations, and controversies surrounding use of the available oral hypoglycemic agents during pregnancy. Obstetricians & Gynecologists, Family Physicians After completion of this article, the reader should be able to describe the mechanisms of actions of the various oral hypoglycemic agents, to list the known side effects of these agents, and to summarize the data on the use of these agents during pregnancy.

  20. Power in Jeopardy: A Poststructuralist Reading of the Arthurian Legend from Malory’s Le Morte d’Arthur and Tennyson’s Idylls of the King to Tolkien’s The Lord of the Rings

    Directory of Open Access Journals (Sweden)

    Timuçin Buğra Edman

    2015-12-01

    Full Text Available Power in Jeopardy: A Poststructuralist Reading of the Arthurian Legend from Malory’s Le Morte d’Arthur and Tennyson’s Idylls of the King to Tolkien’s The Lord of the Rings Abstract The days of the classical heroes are over, as the days of Romance or Chivalric Romance and Epic that depict the hero in quest of the ideal are. A typical Romance situates the hero in a succession of challenges, each of which is overcome by him, who finally defeats the dark, evil force and brings peace and order to his community, thus offering to it the opportunity of living in a system defined by the norms of universal morality and enlightenment. The hero becomes a model of universal justice and stability, and he towers above all of his fellow men as a symbol of perfection and endurance of will against the powers of darkness. This plot of one-man challenge and task has been much fruitful in the creation of the stories of the pre-Christian times, the times of the foundation and expansion of Christianity, and the Medieval Age. During these eras such legendary figures as Osiris, Prometheus, Moses, Jesus Christ, and King Arthur of England have emerged as representative perfect super heroes and as universal and absolute role models. Known as monomyths, such stories have shown parallelism regarding the character and plot structure, all yielding similarities as dictated by Romance; this is mostly obvious through the continuous clash of good and evil. The clash creates a sustained tension in the reader whose moral understanding and conscience are kept busy in wondering whether the hero will lose the battle of righteousness or win it, announcing that human dignity has once again been victorious over evil forces. As suggested above, the days of such heroes are over, together with their references to super human qualities which have long been referred to as universal symbols that stand for ideal models for humanity. Such symbols, signifiers, refer to a sign both in

  1. 13 CFR 120.952 - Fiscal agent.

    Science.gov (United States)

    2010-01-01

    ... Loan Program (504) Debenture Sales and Service Agents § 120.952 Fiscal agent. SBA shall appoint a Fiscal Agent to assess the financial markets, minimize the cost of sales, arrange for the production of...

  2. Homeostatic Agent for General Environment

    Science.gov (United States)

    Yoshida, Naoto

    2018-03-01

    One of the essential aspect in biological agents is dynamic stability. This aspect, called homeostasis, is widely discussed in ethology, neuroscience and during the early stages of artificial intelligence. Ashby's homeostats are general-purpose learning machines for stabilizing essential variables of the agent in the face of general environments. However, despite their generality, the original homeostats couldn't be scaled because they searched their parameters randomly. In this paper, first we re-define the objective of homeostats as the maximization of a multi-step survival probability from the view point of sequential decision theory and probabilistic theory. Then we show that this optimization problem can be treated by using reinforcement learning algorithms with special agent architectures and theoretically-derived intrinsic reward functions. Finally we empirically demonstrate that agents with our architecture automatically learn to survive in a given environment, including environments with visual stimuli. Our survival agents can learn to eat food, avoid poison and stabilize essential variables through theoretically-derived single intrinsic reward formulations.

  3. Agent Based Individual Traffic Guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen

    This thesis investigates the possibilities in applying Operations Research (OR) to autonomous vehicular traffic. The explicit difference to most other research today is that we presume that an agent is present in every vehicle - hence Agent Based Individual Traffic guidance (ABIT). The next...... evolutionary step for the in-vehicle route planners is the introduction of two-way communication. We presume that the agent is capable of exactly this. Based on this presumption we discuss the possibilities and define a taxonomy and use this to discuss the ABIT system. Based on a set of scenarios we conclude...... that the system can be divided into two separate constituents. The immediate dispersion, which is used for small areas and quick response, and the individual alleviation, which considers the longer distance decision support. Both of these require intrinsicate models and cost functions which at the beginning...

  4. Agent review phase one report.

    Energy Technology Data Exchange (ETDEWEB)

    Zubelewicz, Alex Tadeusz; Davis, Christopher Edward; Bauer, Travis LaDell

    2009-12-01

    This report summarizes the findings for phase one of the agent review and discusses the review methods and results. The phase one review identified a short list of agent systems that would prove most useful in the service architecture of an information management, analysis, and retrieval system. Reviewers evaluated open-source and commercial multi-agent systems and scored them based upon viability, uniqueness, ease of development, ease of deployment, and ease of integration with other products. Based on these criteria, reviewers identified the ten most appropriate systems. The report also mentions several systems that reviewers deemed noteworthy for the ideas they implement, even if those systems are not the best choices for information management purposes.

  5. Dual Rationality and Deliberative Agents

    Science.gov (United States)

    Debenham, John; Sierra, Carles

    Human agents deliberate using models based on reason for only a minute proportion of the decisions that they make. In stark contrast, the deliberation of artificial agents is heavily dominated by formal models based on reason such as game theory, decision theory and logic—despite that fact that formal reasoning will not necessarily lead to superior real-world decisions. Further the Nobel Laureate Friedrich Hayek warns us of the ‘fatal conceit’ in controlling deliberative systems using models based on reason as the particular model chosen will then shape the system’s future and either impede, or eventually destroy, the subtle evolutionary processes that are an integral part of human systems and institutions, and are crucial to their evolution and long-term survival. We describe an architecture for artificial agents that is founded on Hayek’s two rationalities and supports the two forms of deliberation used by mankind.

  6. Monitoring presence of chemical agents

    International Nuclear Information System (INIS)

    Preston, J.M.

    1984-01-01

    The specification describes a case for use with a hand-portable chemical agent detector for continuously monitoring an atmosphere for the presence of predetermined chemical agents. The detector having means for ionizing air samples and providing at an output terminal electrical signals representative of the mobility spectrum of ionized chemical vapours produced by the ionizing means. The case comprises means for defining a chamber in the case for supporting and removably enclosing the detector, means for communicating ambient atmosphere to the chamber, electrical circuit means in the case, the circuit means being adapted to be detachably connected to the detector output terminal when the detector is positioned in the chamber and being responsive to the electrical signals for producing an alarm signal when the signals detect a chemical agent concentration in the atmosphere exceeding a predetermined concentration level, and alarm means responsive to the alarm signal. (author)

  7. Solidifying agent for radioactive waste

    International Nuclear Information System (INIS)

    Kida, Tsutomu; Sakai, Etsuro.

    1988-01-01

    Purpose: To increase the processing performance even when the iodine content is great and obtain solidification products of excellent durability. Constitution: The solidifying agent mainly comprises waterhardenable material, calcium aluminate (CA), gypsum, ultrafine powder and high performance water reducer. As the water hardenable material, mixed cement incorporated with portland cement, for example, is used. CA with CAO/Al 2 O 3 molar ratio of about 1.5 - 4 is used. Gypsum dihydrate is used as the gypsum in an amount of about 2 to 19 parts by weight based on 29 to 93 parts by weight of water-hardenable materials. The average grain size of the ultrafine powder is lower by about one digit than that of water-hardenable material, CA and gypsum and, for example, silica dust is used. The high performance water reducing agent is a surface active agent, for example, mainly comprising naphthalene sulfonate, etc. (Yoshio, Y.)

  8. Thyroid Dysfunction from Antineoplastic Agents

    Science.gov (United States)

    Larsen, P. Reed; Marqusee, Ellen

    2011-01-01

    Unlike cytotoxic agents that indiscriminately affect rapidly dividing cells, newer antineoplastic agents such as targeted therapies and immunotherapies are associated with thyroid dysfunction. These include tyrosine kinase inhibitors, bexarotene, radioiodine-based cancer therapies, denileukin diftitox, alemtuzumab, interferon-α, interleukin-2, ipilimumab, tremelimumab, thalidomide, and lenalidomide. Primary hypothyroidism is the most common side effect, although thyrotoxicosis and effects on thyroid-stimulating hormone secretion and thyroid hormone metabolism have also been described. Most agents cause thyroid dysfunction in 20%–50% of patients, although some have even higher rates. Despite this, physicians may overlook drug-induced thyroid dysfunction because of the complexity of the clinical picture in the cancer patient. Symptoms of hypothyroidism, such as fatigue, weakness, depression, memory loss, cold intolerance, and cardiovascular effects, may be incorrectly attributed to the primary disease or to the antineoplastic agent. Underdiagnosis of thyroid dysfunction can have important consequences for cancer patient management. At a minimum, the symptoms will adversely affect the patient’s quality of life. Alternatively, such symptoms can lead to dose reductions of potentially life-saving therapies. Hypothyroidism can also alter the kinetics and clearance of medications, which may lead to undesirable side effects. Thyrotoxicosis can be mistaken for sepsis or a nonendocrinologic drug side effect. In some patients, thyroid disease may indicate a higher likelihood of tumor response to the agent. Both hypothyroidism and thyrotoxicosis are easily diagnosed with inexpensive and specific tests. In many patients, particularly those with hypothyroidism, the treatment is straightforward. We therefore recommend routine testing for thyroid abnormalities in patients receiving these antineoplastic agents. PMID:22010182

  9. Intelligent agent software for medicine.

    Science.gov (United States)

    Lieberman, Henry; Mason, Cindy

    2002-01-01

    An important trend for the future of health technology will be the increasing use of intelligent agent software for medical applications. As the complexity of situations faced by both patients and health care providers grows, conventional interfaces that rely on users to manually transfer data and manually perform each problem-solving step, won't be able to keep up. This article describes how software agents that incorporate learning, personalization, proactivity, context-sensitivity and collaboration will lead to a new generation of medical applications that will streamline user interfaces and enable more sophisticated communication and problem-solving.

  10. Autonomous sensor manager agents (ASMA)

    Science.gov (United States)

    Osadciw, Lisa A.

    2004-04-01

    Autonomous sensor manager agents are presented as an algorithm to perform sensor management within a multisensor fusion network. The design of the hybrid ant system/particle swarm agents is described in detail with some insight into their performance. Although the algorithm is designed for the general sensor management problem, a simulation example involving 2 radar systems is presented. Algorithmic parameters are determined by the size of the region covered by the sensor network, the number of sensors, and the number of parameters to be selected. With straight forward modifications, this algorithm can be adapted for most sensor management problems.

  11. Clustering recommendations to compute agent reputation

    Science.gov (United States)

    Bedi, Punam; Kaur, Harmeet

    2005-03-01

    Traditional centralized approaches to security are difficult to apply to multi-agent systems which are used nowadays in e-commerce applications. Developing a notion of trust that is based on the reputation of an agent can provide a softer notion of security that is sufficient for many multi-agent applications. Our paper proposes a mechanism for computing reputation of the trustee agent for use by the trustier agent. The trustier agent computes the reputation based on its own experience as well as the experience the peer agents have with the trustee agents. The trustier agents intentionally interact with the peer agents to get their experience information in the form of recommendations. We have also considered the case of unintentional encounters between the referee agents and the trustee agent, which can be directly between them or indirectly through a set of interacting agents. The clustering is done to filter off the noise in the recommendations in the form of outliers. The trustier agent clusters the recommendations received from referee agents on the basis of the distances between recommendations using the hierarchical agglomerative method. The dendogram hence obtained is cut at the required similarity level which restricts the maximum distance between any two recommendations within a cluster. The cluster with maximum number of elements denotes the views of the majority of recommenders. The center of this cluster represents the reputation of the trustee agent which can be computed using c-means algorithm.

  12. 2APL: a practical agent programming language

    NARCIS (Netherlands)

    Dastani, M.M.

    2008-01-01

    This article presents a BDI-based agent-oriented programming language, called 2APL (A Practical Agent Programming Language). This programming language facilitates the implementation ofmulti-agent systems consisting of individual agents thatmay share and access external environments. It realizes

  13. Fundamental studies of oral contrast agents for MR. Comparison of manganese agent and iron agent

    International Nuclear Information System (INIS)

    Fujita, Osamu; Hiraishi, Kumiko; Suginobu, Yoshito; Takeuchi, Masayasu; Narabayashi, Isamu

    1996-01-01

    We investigated and compared signal intensity and the effect of imaging the upper abdomen with blueberry juice (B.J.), a Mn agent utilizing the properties of paramagnetic metals, and FerriSeltz (F.S.), an iron agent. Since the relaxation effect was much stronger with B.J. than with F.S., the signal intensity required of a peroral contrast agent was able to be obtained at a much lower concentration of B.J. In imaging the upper abdomen, B.J. had a positive effect on imaging in T1-weighted images, and a negative effect in T2-weighted images. F.S. had a positive imaging effect in both, and because it showed extremely high signals in T2-weighted images, motion artifact arose. (author)

  14. Dopamine agents for hepatic encephalopathy

    DEFF Research Database (Denmark)

    Junker, Anders Ellekær; Als-Nielsen, Bodil; Gluud, Christian

    2014-01-01

    BACKGROUND: Patients with hepatic encephalopathy may present with extrapyramidal symptoms and changes in basal ganglia. These changes are similar to those seen in patients with Parkinson's disease. Dopamine agents (such as bromocriptine and levodopa, used for patients with Parkinson's disease) have...

  15. Agent Supported Serious Game Environment

    Science.gov (United States)

    Terzidou, Theodouli; Tsiatsos, Thrasyvoulos; Miliou, Christina; Sourvinou, Athanasia

    2016-01-01

    This study proposes and applies a novel concept for an AI enhanced serious game collaborative environment as a supplementary learning tool in tertiary education. It is based on previous research that investigated pedagogical agents for a serious game in the OpenSim environment. The proposed AI features to support the serious game are the…

  16. 13 CFR 108.1620 - Functions of agents, including Central Registration Agent, Selling Agent and Fiscal Agent.

    Science.gov (United States)

    2010-01-01

    ... Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM SBA Financial Assistance for NMVC Companies (Leverage) Funding Leverage by Use of Sba Guaranteed Trust Certificates (âtcsâ... Debenture, SBA may cause each NMVC Company to appoint a Selling Agent to perform functions that include, but...

  17. Design of Collaborative Information Agents

    NARCIS (Netherlands)

    Jonker, C.M.; Klusch, M.; Treur, J.; Klusch, M.; Kerschberg, L.

    2000-01-01

    Effective development of nontrivial systems of collaborative information agents requires that an in-depth analysis is made resulting in (1) specification of requirements at different levels of the system, (2) specification of design structures, and (3) a systematic verification. To support a

  18. Raspberry Pi for secret agents

    CERN Document Server

    Sjogelid, Stefan

    2015-01-01

    This book is an easy-to-follow guide with practical examples in each chapter. Suitable for the novice and expert alike, each topic provides a fast and easy way to get started with exciting applications and also guides you through setting up the Raspberry Pi as a secret agent toolbox.

  19. Voice in the Agentic Assemblage

    Science.gov (United States)

    Mazzei, Lisa A.; Jackson, Alecia Y.

    2017-01-01

    In this article, we explore how a posthumanist stance has enabled us to work a different consideration of the way in which "voice" is constituted and constituting in educational inquiry; that is, we position voice in a posthuman ontology that is understood as attributable to a complex network of human and nonhuman agents that exceed the…

  20. Strategic management of biotechnology agents.

    Science.gov (United States)

    Huber, S L

    1993-07-01

    The use of biologic response modifiers to demonstrate a value-driven approach to strategic management by pharmacists is described. To participate in decisions on the use of technology in their institutions, pharmacists must practice strategic management. This process includes environmental scanning, analysis of clinical and pharmacoeconomic data, and development of clinical management approaches. It is ideal for analyzing biologic response modifiers such as filgrastim and sargramostim. Emphasis must be placed on maximizing the fit among the products, the institution, and the health care environment. Pharmacists will find plentiful opportunities for clinical management with biotechnology agents. Practitioners who specialize in determining the total cost of care by using pharmacoeconomic methods are needed, as are practitioners trained to monitor the complicated biotechnology agents. Also, the institution needs to forecast accurately the impact of emerging biotechnology agents. If pharmacists can develop and control clinical, pharmacoeconomic, and reimbursement information databases for biotechnology agents, the pharmacy profession will be in a strong position to meet the challenges of biotechnology and realize the inherent opportunities.

  1. Bridging humans via agent networks

    International Nuclear Information System (INIS)

    Ishida, Toru

    1994-01-01

    Recent drastic advance in telecommunication networks enabled the human organization of new class, teleorganization, which differ from any existing organization in that the organization which is easy to create by using telecommunication networks is virtual and remote, that people can join multiple organizations simultaneously, and that the organization can involve people who may not know each other. In order to enjoy the recent advance in telecommunication, the agent networks to help people organize themselves are needed. In this paper, an architecture of agent networks, in which each agent learns the preference or the utility functioin of the owner, and acts on behalf of the owner in maintaining the organization, is proposed. When an agent networks supports a human organization, the conventional human interface is divided into personal and social interfaces. The functionalities of the social interface in teleconferencing and telelearning were investigated. In both cases, the existence of B-ISDN is assumed, and the extension to the business meeting scheduling using personal handy phone (PHS) networks with personal digital assistant (PDA) terminals is expected. These circumstances are described. Mutual selection protocols (MSP) and their dynamic properties are explained. (K.I.)

  2. Hyperthermia as a teratogenic agent

    Science.gov (United States)

    Poswillo, David; Nunnerley, Heather; Sopher, Dinah; Keith, John

    1974-01-01

    The common cotton-eared marmoset, a nonhuman primate with a narrow zone of thermoneutrality, was used in an experiment to assess the effects of hyperthermia as a teratogenic agent. Mild heat stress conditions were used. The results of this preliminary study justify further investigation of the effect of hyperthermia on the primate embryo during morphogenesis. Imagesp173-a PMID:4214348

  3. Real Estate Agent Commission Disputes

    Directory of Open Access Journals (Sweden)

    Anida Duarte

    2015-06-01

    Full Text Available The purpose of this study was to examine the relationship among Procuring Cause Law, real estate agent years of experience, and real estate commission disputes. A pilot survey was conducted in the southwestern United States among real estate agents, realtor(s, and brokers. After testing the hypothesis, the decision was made to fail to reject the hypothesis and conclude that real estate agent experience and not Procuring Cause Law produced favorable outcomes in disputes. As a result, the following recommendations were made: (a Agency seller and buyer’s agreements should be used in each transaction to avoid disputes, (b proper expectations and guidelines should be reviewed prior to starting any real estate transaction, (c a checklist may assist in the assurance that all valuable information is reviewed, (d agents could benefit from fully understanding Procuring Cause Law and sharing this information with their clients, (e state and national regulatory requirements of the law could be modified for easier understanding and use, and (f consumers who willfully violate the law could be subject to monetary penalties.

  4. The DARPA agent markup language

    NARCIS (Netherlands)

    Lassila, O; van Harmelen, F; Horrocks, I.; Hendler, J.; McGuinness, DL

    2000-01-01

    The DARPA Agent Markup Language (DAML) program is a United States government sponsored endeavor aimed at providing the foundation for the next web evolution – the semantic web. The program is funding critical research to develop languages, tools and techniques for making considerably more of the

  5. Kriitikute lemmikfilm on "Agent Sinikael"

    Index Scriptorium Estoniae

    2003-01-01

    Eesti Filmiajakirjanike Ühing andis kümnendat korda välja auhinda Aasta film 2002. Parimaks filmiks tunnistati mängufilm "Agent Sinikael" : režissöör Marko Raat. Viimane sai preemiaks Neitsi Maali kuju ja 12 000 krooni

  6. Biocontrol agents in signalling resistance

    NARCIS (Netherlands)

    Loon, L.C. van; Pieterse, C.M.J.

    2002-01-01

    The mechanisms by which biological control agents suppress disease comprise competition for nutrients, notably iron, production of antibiotics, and secretion of lytic enzymes, as well as inducing resistance in the plant. The former three mechanisms act primarily on the pathogen by decreasing its

  7. The Power Trading Agent Competition

    NARCIS (Netherlands)

    W. Ketter (Wolfgang); J. Collins (John); P. Reddy (Prashant); C. Flath (Christoph); M.M. de Weerdt (Mathijs)

    2011-01-01

    textabstractThis is the specification for the Power Trading Agent Competition for 2012 (Power TAC 2012). Power TAC is a competitive simulation that models a “liberalized” retail electrical energy market, where competing business entities or “brokers” offer energy services to customers through tariff

  8. The Power Trading Agent Competition

    NARCIS (Netherlands)

    Ketter, W.; Collins, J.; Reddy, P.; Flath, C.; De Weerdt, M.M.

    2011-01-01

    This is the specification for the Power Trading Agent Competition for 2012 (Power TAC 2012). Power TAC is a competitive simulation that models a “liberalized” retail electrical energy market, where competing business entities or “brokers” offer energy services to customers through tariff contracts,

  9. Agents containing chlorhexidine in dentistry

    Directory of Open Access Journals (Sweden)

    Lebedeva S.N.

    2011-03-01

    Full Text Available Aclinical definition of the efficacy of chlorhexidine-containing means for reducing the risk of dental caries and gingivitis with plastic caps. Chlorhexidine is an effective antimicrobial agent for the formation of individual programs for the prevention of dental caries

  10. Humor and Embodied Conversational Agents

    NARCIS (Netherlands)

    Nijholt, Antinus

    This report surveys the role of humor in human-to-human interaction and the possible role of humor in human-computer interaction. The aim is to see whether it is useful for embodied conversational agents to integrate humor capabilities in their internal model of intelligence, emotions and

  11. Tc-99m imaging agents

    International Nuclear Information System (INIS)

    Weininger, J.; Trumper, J.

    1984-01-01

    A wide range of pharmaceuticals for labeling with Tc-99m, developed by the Soreq Radiopharmaceuticals Department, is described. Details of the production and quality control of 13 kits are given, as well as the range of results required for consistently high quality imaging agents

  12. Travel Agent. Occupational Simulation Kit.

    Science.gov (United States)

    Peterson, Wayne

    This career exploration instructional booklet on the travel agent's occupation is one of several resulting from the rural southwestern Colorado CEPAC Project (Career Education Process of Attitude Change). Based on a job analysis and utilizing a programed instructional format, the following content is included: A brief description of what a travel…

  13. SEM: A Cultural Change Agent

    Science.gov (United States)

    Barnes, Bradley; Bourke, Brian

    2015-01-01

    The authors advance the concept that institutional culture is a purposeful framework by which to view SEM's utility, particularly as a cultural change agent. Through the connection of seemingly independent functions of performance and behavior, implications emerge that deepen the understanding of the influence of culture on performance outcomes…

  14. Halide test agent replacement study

    Energy Technology Data Exchange (ETDEWEB)

    Banks, E.M.; Freeman, W.P.; Kovach, B.J. [and others

    1995-02-01

    The intended phaseout of the chlorofluorocarbons (CFCs) from commercial use required the evaluation of substitute materials for the testing for leak paths through both individual adsorbers and installed adsorbent banks. The American Society of Mechanical Engineers (ASME) Committee on Nuclear Air and Gas Treatment (CONAGT) is in charge of maintaining the standards and codes specifying adsorbent leak test methods for the nuclear safety related air cleaning systems. The currently published standards and codes cite the use of R-11, R-12 and R-112 for leak path test agents. All of these compounds are CFCs. There are other agencies and organizations (USDOE, USDOD and USNRC) also specifying testing for leak paths or in some cases for special life tests using the above compounds. The CONAGT has recently developed criteria for the suitability evaluation of substitute test agents. On the basis of these criteria, several compounds were evaluated for their acceptability as adsorbent bed leak and life test agents. The ASME CONAGT Test Agent Qualification Criteria. The test agent qualification is based on the following parameters: (1) Similar retention times on activated carbons at the same concentration levels as one of the following: R-11, R-12, R-112 or R-112a. (2) Similar lower detection limit sensitivity and precision in the concentration range of use as R-11, R-12, R-112 and R-112a. (3) Gives the same in-place leak test results as R-11, R-12, R-112, or R-112a. (4) Chemical and radiological stability under the use conditions. (5) Causes no degradation of the carbon and its impregnant or of the other NATS components under the use conditions. (6) Is listed in the USEPA Toxic Substances Control Act (TSCA) inventory for commercial use.

  15. Limonene and tetrahydrofurfurly alcohol cleaning agent

    Science.gov (United States)

    Bohnert, George W.; Carter, Richard D.; Hand, Thomas E.; Powers, Michael T.

    1997-10-21

    The present invention is a tetrahydrofurfuryl alcohol and limonene cleaning agent and method for formulating and/or using the cleaning agent. This cleaning agent effectively removes both polar and nonpolar contaminants from various electrical and mechanical parts and is readily used without surfactants, thereby reducing the need for additional cleaning operations. The cleaning agent is warm water rinsable without the use of surfactants. The cleaning agent can be azeotropic, enhancing ease of use in cleaning operations and ease of recycling.

  16. Limonene and tetrahydrofurfuryl alcohol cleaning agent

    Science.gov (United States)

    Bohnert, George W.; Carter, Richard D.; Hand, Thomas E.; Powers, Michael T.

    1996-05-07

    The present invention is a tetrahydrofurfuryl alcohol and limonene or terpineol cleaning agent and method for formulating and/or using the cleaning agent. This cleaning agent effectively removes both polar and nonpolar contaminants from various electrical and mechanical parts and is readily used without surfactants, thereby reducing the need for additional cleaning operations. The cleaning agent is warm water rinsable without the use of surfactants. The cleaning agent can be azeotropic, enhancing ease of use in cleaning operations and ease of recycling.

  17. Limonene and tetrahydrofurfuryl alcohol cleaning agent

    Science.gov (United States)

    Bohnert, G.W.; Carter, R.D.; Hand, T.E.; Powers, M.T.

    1997-10-21

    The present invention is a tetrahydrofurfuryl alcohol and limonene cleaning agent and method for formulating and/or using the cleaning agent. This cleaning agent effectively removes both polar and nonpolar contaminants from various electrical and mechanical parts and is readily used without surfactants, thereby reducing the need for additional cleaning operations. The cleaning agent is warm water rinsable without the use of surfactants. The cleaning agent can be azeotropic, enhancing ease of use in cleaning operations and ease of recycling.

  18. Innovative agents in cancer prevention.

    Science.gov (United States)

    Manson, Margaret M; Farmer, Peter B; Gescher, Andreas; Steward, William P

    2005-01-01

    There are many facets to cancer prevention: a good diet, weight control and physical activity, a healthy environment, avoidance of carcinogens such as those in tobacco smoke, and screening of populations at risk to allow early detection. But there is also the possibility of using drugs or naturally occurring compounds to prevent initiation of, or to suppress, tumour growth. Only a few such agents have been used to date in the clinic with any success, and these include non-steroidal anti-inflammatory drugs for colon, finasteride for prostate and tamoxifen or raloxifene for breast tumours. An ideal chemopreventive agent would restore normal growth control to a preneoplastic or cancerous cell population by modifying aberrant signalling pathways or inducing apoptosis (or both) in cells beyond repair. Characteristics for such an agent include selectivity for damaged or transformed cells, good bioavailability and more than one mechanism of action to foil redundancy or crosstalk in signalling pathways. As more research effort is being targeted towards this area, the distinction between chemotherapeutic and chemopreventive agents is blurring. Chemotherapeutic drugs are now being designed to target over- or under-active signalling molecules within cancer cells, a philosophy which is just as relevant in chemoprevention. Development of dietary agents is particularly attractive because of our long-standing exposure to them, their relative lack of toxicity, and encouraging indications from epidemiology. The carcinogenic process relies on the cell's ability to proliferate abnormally, evade apoptosis, induce angiogenesis and metastasise to distant sites. In vitro studies with a number of different diet-derived compounds suggest that there are molecules capable of modulating each of these aspects of tumour growth. However, on the negative side many of them have rather poor bioavailability. The challenge is to uncover their multiple mechanisms of action in order to predict their

  19. Does an Agent Matter? The Effects of Animated Pedagogical Agents on Multimedia Environments.

    Science.gov (United States)

    Craig, Scotty D.; Gholson, Barry

    Data are presented on the effects of Animated Agents on multimedia learning environments with specific concerns of split attention and modality effects. The study was a 3 (agent properties: agent only, agent with gestures, no agent) x 3 (picture features: static picture, sudden onset, animation) factorial design with outcome measures of mental…

  20. CATS-based Agents That Err

    Science.gov (United States)

    Callantine, Todd J.

    2002-01-01

    This report describes preliminary research on intelligent agents that make errors. Such agents are crucial to the development of novel agent-based techniques for assessing system safety. The agents extend an agent architecture derived from the Crew Activity Tracking System that has been used as the basis for air traffic controller agents. The report first reviews several error taxonomies. Next, it presents an overview of the air traffic controller agents, then details several mechanisms for causing the agents to err in realistic ways. The report presents a performance assessment of the error-generating agents, and identifies directions for further research. The research was supported by the System-Wide Accident Prevention element of the FAA/NASA Aviation Safety Program.

  1. Software agents in molecular computational biology.

    Science.gov (United States)

    Keele, John W; Wray, James E

    2005-12-01

    Progress made in applying agent systems to molecular computational biology is reviewed and strategies by which to exploit agent technology to greater advantage are investigated. Communities of software agents could play an important role in helping genome scientists design reagents for future research. The advent of genome sequencing in cattle and swine increases the complexity of data analysis required to conduct research in livestock genomics. Databases are always expanding and semantic differences among data are common. Agent platforms have been developed to deal with generic issues such as agent communication, life cycle management and advertisement of services (white and yellow pages). This frees computational biologists from the drudgery of having to re-invent the wheel on these common chores, giving them more time to focus on biology and bioinformatics. Agent platforms that comply with the Foundation for Intelligent Physical Agents (FIPA) standards are able to interoperate. In other words, agents developed on different platforms can communicate and cooperate with one another if domain-specific higher-level communication protocol details are agreed upon between different agent developers. Many software agent platforms are peer-to-peer, which means that even if some of the agents and data repositories are temporarily unavailable, a subset of the goals of the system can still be met. Past use of software agents in bioinformatics indicates that an agent approach should prove fruitful. Examination of current problems in bioinformatics indicates that existing agent platforms should be adaptable to novel situations.

  2. Children as digital rights agents

    DEFF Research Database (Denmark)

    Stald, Gitte Bang

    2016-01-01

    the role of the “adult world” is. We need to focus more on the active role that children and adolescents play, according to age, skills and various capacities, in identifying, reflecting upon and acting according to opportunities and challenges in relation to digital media and digital rights (Hartman et al...... 2007). The paper presents a model for analyzing the intersecting levels of children as agents in relation to digital risks and rights: Children as peer-to-peer agents. Children provide mutual practical guidance; experience sharing; advice. re. to risk and harm. Children as advocates/ politicians....... Children participate in youth parliaments; media councils; Safer Internet day; IGF; NGOs, Children as informants. Children contribute to research; media coverage; content providers; reporters (of negative content/ behavior The model is primarily supported by empirical data from the Net Children Go Mobile...

  3. Extension agents and conflict narratives

    DEFF Research Database (Denmark)

    Bond, Jennifer Lauren

    2016-01-01

    conflict. Originality: This work contributes to a growing body of literature interested in the role of extension agents in conflict management. By applying Q methodology, this work has shown that while extension agents are involved in conflict management, their perceptions of these conflicts are subjective......Purpose: This work investigated the narratives of development extensionists in relation to natural resource conflict, in order to understand the competing discourses surrounding the wicked problems of natural resource management in Laikipia County, Kenya. Methodology: Q methodology was used...... to elicit the conflict narratives present among extension professionals. A concourse of 221 statements were devised from interviews and group discussions with key informants and a final sample of 49 statements was used for the sorting. Thirteen Q-sorts were undertaken with among rural extension...

  4. Logical Theories for Agent Introspection

    DEFF Research Database (Denmark)

    Bolander, Thomas

    2004-01-01

    Artificial intelligence systems (agents) generally have models of the environments they inhabit which they use for representing facts, for reasoning about these facts and for planning actions. Much intelligent behaviour seems to involve an ability to model not only one's external environment...... introspective reasoning, the presence of self-reference causes the theory to be prone to inconsistency. The challenge therefore becomes to construct logical theories supporting introspective reasoning while at the same time ensuring that consistency is retained. In the thesis, we meet this challenge by devising...... by developments within semantics for logic programming within computational logic and formal theories of truth within philosophical logic. The thesis provides a number of examples showing how the developed theories can be used as reasoning frameworks for agents with introspective abilities. In Danish...

  5. Solidifying agent for radioactive waste

    International Nuclear Information System (INIS)

    Sakai, Etsuro; Kida, Tsutomu; Sasagawa, Yukio.

    1988-01-01

    Purpose: To apply solidifying treatment to boron-containing radioactive wastes while improving the durability, rapid hardening property and processing performance, as well as reducing the leaching property. Constitution: A solidifying agent comprising calcium aluminate having CaO and Al 2 O 3 at 1.5 - 4 molar ratio, super fine powder and high performance moderator is used. As the super fine powder, those having a grain size smaller by 1 - 2 orders than that of the calcium aluminate are preferred. Specifically, there can be used silica dust, calcium carbonate, silica gel, titanium oxide, aluminum oxide, etc. As the moderator, there are used those surface active agents of great dispersing performance not causing excess delay for coagulation or excess air entrainment when added in a great amount to cements. Specifically, there can be mentioned those mainly composed of salts of naphthalene sulfonic acid-formaldehyde condensates, salts of melamine sulfonic acid formaldehyde condensates, etc. (Ikeda, J.)

  6. Strategic Design of Mobile Agents

    OpenAIRE

    Vulkan, Nir

    2002-01-01

    Much of the economic value of electronic commerce comes from the automation of interactions between businesses and individuals. Game theory is a useful set of tools that can be used by designers of electronic-commerce applications in analyzing and engineering of automated agents and communication protocols. The central theoretical concept used in game theory is the Nash equilibrium. In this article, I show how the outcomes supported by a Nash equilibrium can positively be enlarged using autom...

  7. Needs, Pains, and Motivations in Autonomous Agents.

    Science.gov (United States)

    Starzyk, Janusz A; Graham, James; Puzio, Leszek

    This paper presents the development of a motivated learning (ML) agent with symbolic I/O. Our earlier work on the ML agent was enhanced, giving it autonomy for interaction with other agents. Specifically, we equipped the agent with drives and pains that establish its motivations to learn how to respond to desired and undesired events and create related abstract goals. The purpose of this paper is to explore the autonomous development of motivations and memory in agents within a simulated environment. The ML agent has been implemented in a virtual environment created within the NeoAxis game engine. Additionally, to illustrate the benefits of an ML-based agent, we compared the performance of our algorithm against various reinforcement learning (RL) algorithms in a dynamic test scenario, and demonstrated that our ML agent learns better than any of the tested RL agents.This paper presents the development of a motivated learning (ML) agent with symbolic I/O. Our earlier work on the ML agent was enhanced, giving it autonomy for interaction with other agents. Specifically, we equipped the agent with drives and pains that establish its motivations to learn how to respond to desired and undesired events and create related abstract goals. The purpose of this paper is to explore the autonomous development of motivations and memory in agents within a simulated environment. The ML agent has been implemented in a virtual environment created within the NeoAxis game engine. Additionally, to illustrate the benefits of an ML-based agent, we compared the performance of our algorithm against various reinforcement learning (RL) algorithms in a dynamic test scenario, and demonstrated that our ML agent learns better than any of the tested RL agents.

  8. Preponderant agent, what is that?

    Directory of Open Access Journals (Sweden)

    Clara Luz Álvarez

    2015-05-01

    Full Text Available Purpose – Preponderant agent is a new instrument for preventing and reverting adverse impact in competition due to highly concentrated markets. Therefore, this paper's objective is to present and analyze the preponderant agent concept in Mexico with emphasis on the broadcast sector, the telecommunication regulator decisions and the courts' interpretation. Methodology/approach/design – The objectives were achieved by researching and analyzing the main legal documents, the Congress reports and debates, the regulator's decisions and other relevant regulator's documents, as well as final decisions by the courts in connection with broadcast sector. Findings – Among the findings are that certain topics were not duly addressed by the Mexican regulator, or by the Congress, whereas the courts were more willing to hold decisions in favor of public interest based on constitutional intent and deference to the regulator's decision. Originality/value – This paper will be valuable for persons interested in telecommunications, broadcast and antitrust. Although the preponderant agent concept created in Mexico is not necessarily a “best practice”, it does provide an alternative instrument in antitrust. Moreover, the courts decisions also provide criteria regarding regulatory deference for the regulator.

  9. Solidification agent for radioactive waste

    International Nuclear Information System (INIS)

    Sakai, Etsuro; Shibayama, Yukio.

    1986-01-01

    Purpose: In low and medium level radioactive waste processing, to obtain superior solidified blocks by mixing cement, super-fine dusts and high-performance water-reducing agent and water to radioactive waste materials for solidification. Constitution: The various types of portland cements available are used for solidification. Silica dust is used as the super-fine dust and has an average article size of one order smaller than that of the cement used for solidification. Napthalene, sulfonic acid formalydehyde condensation salts etc. are used as the water-reducing agents. For example, for hundred units, by weight, of cement and super-fine dust 10 units (by solid content) are added. Furthermore, smaller quantities of water are desirable. By mixing the radioactive wastes with cement, super-fine dust, water-reducing agents, and water, the solidified material shows superior chemical resistance and durability. The processing capacity is also increased. Furthermore, a more leach resistant solid can be obtained for storage. (Takahashi, M.)

  10. Overprescribing of lipid lowering agents.

    Science.gov (United States)

    Smith, M A; Cox, E D; Bartell, J M

    2006-08-01

    Undertreatment of hyperlipidemia has received considerable attention. However, little is known about trends in overprescribing of lipid lowering agents. We examined these trends and their associations with physician, practice, and organisational factors. 2034 physicians were surveyed twice: baseline (1996-7) and follow up (1998-9). On each occasion they were asked: "For what percentage of 50 year old men without other cardiac risk factors would you recommend an oral agent for total cholesterol of 240, LDL 150, and HDL 50 after 6 months on a low cholesterol diet?" During the survey period the National Cholesterol Education Program guidelines did not recommend prescribing for these patients. Binomial and multinomial logistic regressions assessed baseline overprescribing and longitudinal changes in overprescribing, accounting for complex sampling. 39% of physicians recommended prescribing at baseline (round 1), increasing at follow up (round 2) to 51% (p overprescribe at baseline were less likely to be board certified (odds ratio (OR) 0.49, 95% confidence interval (CI) 0.38 to 0.63; p overprescribing to be international medical graduates (OR 2.09, 95% CI 1.20 to 3.64; p = 0.011) and to spend more hours in patient care (OR 1.14, 95% CI 1.03 to 1.26; p = 0.016). Overprescribing of lipid lowering agents is commonplace and increased. At baseline and longitudinally, overprescribing was primarily associated with physician and practice characteristics and not with organisational factors.

  11. Commission of the commercial agent

    Directory of Open Access Journals (Sweden)

    Radović Mirjana

    2015-01-01

    Full Text Available In this paper the author analyses the commercial agent's commission as the most important type of remuneration for commercial agency. In the European Union the issue of commercial agent's commission is regulated in the Directive 86/653/EEC on self-employed commercial agents, whereas the Serbian Law on Obligations has still not been harmonised with those rules. Such state of law would change if and when the new Serbian Civil Code is enacted, since its latest Draft contains numerous new solutions, which were inspired by the Directive. The first part of the paper is dedicated to defining the term 'commission' and its distinguishing from the wider term 'remuneration'. Thereafter, the main types of commission are explained. The following part investigates whether the commission or its specific type constitutes essentialia or naturalia negotii of the contract on commercial agency. Finally, the last part of the paper deals with the amount and the extent of covering costs by the commission, in the absence of any agreement on that matter.

  12. Yalanlamalı Destanlar İle Gelin-Kaynana Manilerinin Mizah Yönünden Benzerlikleri Comparison Of Legends With Denial And Bride-Mother-İn-Law Turkish Poems İn View Of Humor

    Directory of Open Access Journals (Sweden)

    Bülent ARI

    2013-09-01

    Full Text Available In our study, it has been revealed that why literary productsinteract with each other is the fact that the main material in almost allof them is human being and his happiness, unhappiness, belief,suffering.Firstly; bride - mother-in-law Turkish poems and legends withdenial, studied in our research, have been defined comprehensively inorder to show their similarities.Then, in order to reveal the similarities of the two kinds in view ofhumor, a classification has been made, and these similarities has beentried to be revealed in categories such as exaggeration, caricaturization,using word games, slang and bad words, humoring by spats.The final part has been ended with conclusion and bibliographyby stating the fact that art strength of legends with spats and mutualTurkish poems is much more than the others, because all strength ofart is put forward for being dominant in these kinds of humors.Although, it both species there is a social problem on the basis of brideand mother-in-law to increase wits, to apply to various inventions forovercoming the rival side, by doing this it focuses on amusing thosewho are there. Cultural products such as this, maket hem think, holdthem a mirror, help them to see themselves.As a result, it is emphasized that someone who says poem(mani and “epic” uses the folk as a material. Çalışmamızda edebi ürünlerin birbirleriyle etkileşiminin temelinde, hemen hemen hepsinin ana malzemesinin insan olması; insanın sevincinin, hüznünün, özleminin, inancının, acısının, çilesinin vb. bu edebi ürünlerin ana konusu olmasının yattığı ortaya konulmuştur.Çalışmamıza konu olan gelin-kaynana manileri ve yalanlamalı türlerin benzerliklerini daha iyi ortaya koyabilme kaygısıyla, makalenin ilk bölümünde mani ve Güldürücü Destanlar üzerine genişçe bir açıklama yapılmıştır.Sonrasında her iki türün mizah yönünden benzerliklerini ortaya koyabilmek amacıyla bir sınıflandırma yapma

  13. 14th International Conference on Practical Applications of Agents and Multi-Agent Systems : Special Sessions

    CERN Document Server

    Escalona, María; Corchuelo, Rafael; Mathieu, Philippe; Vale, Zita; Campbell, Andrew; Rossi, Silvia; Adam, Emmanuel; Jiménez-López, María; Navarro, Elena; Moreno, María

    2016-01-01

    PAAMS, the International Conference on Practical Applications of Agents and Multi-Agent Systems is an evolution of the International Workshop on Practical Applications of Agents and Multi-Agent Systems. PAAMS is an international yearly tribune to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development of Agents and Multi-Agent Systems. This volume presents the papers that have been accepted for the 2016 in the special sessions: Agents Behaviours and Artificial Markets (ABAM); Advances on Demand Response and Renewable Energy Sources in Agent Based Smart Grids (ADRESS); Agents and Mobile Devices (AM); Agent Methodologies for Intelligent Robotics Applications (AMIRA); Learning, Agents and Formal Languages (LAFLang); Multi-Agent Systems and Ambient Intelligence (MASMAI); Web Mining and ...

  14. S Chandrasekhar the man behind the legend

    CERN Document Server

    1997-01-01

    Subrahmanyan Chandrasekhar - known simply as Chandra throughout the scientific world - has become a legendary figure for his prolific contributions to physics, astrophysics, and applied mathematics. Before his death in 1995, Chandra had forbidden a memorial of the conventional sort, celebrating his life. This book, which contains some thirty articles by his former students, his associates, and his colleagues, is in a sense a memorial volume. It says little about Chandra's great scientific achievements, but shows his human side and the various facets of his brilliant personality, his incredible

  15. Rock legends the asteroids and their discoverers

    CERN Document Server

    Murdin, Paul

    2016-01-01

    This book relates the history of asteroid discoveries and christenings, from those of the early pioneering giants of Hersehel and Piazzi to modern-day amateurs. Moving from history and anecdotal information to science, the book's structure is provided by the names of the asteroids, including one named after the author. Free from a need to conform to scientific naming conventions, the names evidence hero-worship, sycophancy, avarice, vanity, whimsy, erudition and wit, revealing the human side of astronomers, especially where controversy has followed the christening. Murdin draws from extensive historical records to explore the debate over these names. Each age reveals its own biases and preferences in the naming process. < Originally regarded as “vermin of the skies,” asteroids are minor planets, rocky scraps left over from the formation of the larger planets, or broken fragments of worlds that have collided. Their scientific classification as “minor” planets makes them seem unimportant, but over th...

  16. Transgenes and protein localization: myths and legends.

    Science.gov (United States)

    Quattrocchio, Francesca M; Spelt, Cornelis; Koes, Ronald

    2013-09-01

    Fluorescent protein (FP) fusions are frequently used to localize and follow the movement of proteins in living cells. However, a consensus is missing about the experimental design and controls that guarantee the reliability of the results. Here, we discuss possible artifacts and try to navigate through the many methods, preferences, and assumptions that surround protein localization in plants that make it difficult to design a universal approach to achieve reliable results. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Endocrine disruption: fact or urban legend?

    Science.gov (United States)

    Nohynek, Gerhard J; Borgert, Christopher J; Dietrich, Daniel; Rozman, Karl K

    2013-12-16

    Endocrine disruptors (EDs) are substances that cause adverse health effects via endocrine-mediated mechanisms in an intact organism or its progeny or (sub) populations. Purported EDCs in personal care products include 4-MBC (UV filter) or parabens that showed oestrogenic activity in screening tests, although regulatory toxicity studies showed no adverse effects on reproductive endpoints. Hormonal potency is the key issue of the safety of EDCs. Oestrogen-based drugs, e.g. the contraceptive pill or the synthetic oestrogen DES, possess potencies up to 7 orders of magnitude higher than those of PCP ingredients; yet, in utero exposure to these drugs did not adversely affect fertility or sexual organ development of offspring unless exposed to extreme doses. Additive effects of EDs are unlikely due to the multitude of mechanisms how substances may produce a hormone-like activity; even after uptake of different substances with a similar mode of action, the possibility of additive effects is reduced by different absorption, metabolism and kinetics. This is supported by a number of studies on mixtures of chemical EDCs. Overall, despite of 20 years of research a human health risk from exposure to low concentrations of exogenous chemical substances with weak hormone-like activities remains an unproven and unlikely hypothesis. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  18. Jimmy Doolittle: The Commander behind the Legend

    Science.gov (United States)

    2015-02-01

    described the job as managing a “shotgun wedding between the aviation and automobile industry.”86 The car manufacturers were not interested in building...December 1988, the couple’s 71st wedding anniversary. Doolit- tle and Glines, I Could Never Be So Lucky Again, 37–38. 9. Doolittle, interview by...final decision is made you will feel able to leave Eaker here.”5 Similarly, during Doolittle’s ceremonial meeting with King George VI on 4 February

  19. Damascus Steel in Legend and in Reality

    Directory of Open Access Journals (Sweden)

    Panseri, Carlo

    1965-12-01

    Full Text Available Anyone who follows the ancient and glorious history of arms, whether as a collector or as a student, has surely in his reading often run across the term damascened steel or Damascus steel, or simply damascus, applied (not always in correct or pertinent fashion to the constituent materials of edged weapons or of the barrels of firearms.

    No disponible

  20. Borrelioses, agentes e vetores Borrelioses, agents and vectors: a review

    Directory of Open Access Journals (Sweden)

    Cleber O. Soares

    2000-03-01

    Full Text Available As borrelioses são enfermidades infecciosas determinadas por espiroquetas do gênero Borrelia, agentes transmissíveis, principalmente, por carrapatos aos animais e/ou ao homem. Nesta revisão são apresentadas e discutidas as enfermidades determinadas por borrélias, bem como as características gerais das espiroquetas, os aspectos relacionados a transmissão por artrópodes, as enfermidades nos animais domésticos e silvestres, quanto aos aspectos biológicos e patológicos, a doença de Lyme como principal zoonose do grupo, a associação de borrélia com outros agentes hematozoários e os métodos diagnósticos e a epidemiologia comparativa entre dados obtidos no Brasil com os de outros países. Estas borrelioses possuem características patológicas, clínicas e epidemiológicas variadas de acordo à região fisiográfica, devido à existência de distintas espécies, genoespécies e cepas; estes aspectos variam ainda em função dos artrópodes vetores, da interação vetor-patógeno e dos ecossistemas distintos.Borrelioses are infectous diseases caused by spirochaetes of the genus Borrelia. They are born mainly through ticks at animals and/or human beings. In this review are shown and discussed five groups of diseases determined by borrelia, general characteristics of the spirochaetes, aspects related to transmission by arthropods, biological and pathological aspects of the diseases in domestic and wild animals, Lyme disease as an important zoonosis, the association of borrelia with other hematozoa agents, the diagnostic methods and the comparative epidemiology with data obtained from Brazil and other countries. The borrelioses have pathological, clinical and epidemiological characteristics which vary according to physiographic regions due to the existence of different species, genospecies and strains of borrelia, of arthropod vectors, vector-agent relationship and of different ecocystems.

  1. Comparison of Communication Models for Mobile Agents

    Directory of Open Access Journals (Sweden)

    Xining Li

    2003-04-01

    Full Text Available An agent is a self-contained process being acting on behalf of a user. A Mobile Agent is an agent roaming the internet to access data and services, and carry out its assigned task remotely. This paper will focus on the communication models for Mobile Agents. Generally speaking, communication models concern with problems of how to name Mobile Agents, how to establish communication relationships, how to trace moving agents, and how to guarantee reliable communication. Some existing MA systems are purely based on RPC-style communication, whereas some adopts asynchronous message passing, or event registration/handling. Different communication concepts suitable for Mobile Agents are well discussed in [1]. However, we will investigate these concepts and existing models from a different point view: how to track down agents and deliver messages in a dynamic, changing world.

  2. Validation of Agent Based Distillation Movement Algorithms

    National Research Council Canada - National Science Library

    Gill, Andrew

    2003-01-01

    Agent based distillations (ABD) are low-resolution abstract models, which can be used to explore questions associated with land combat operations in a short period of time Movement of agents within the EINSTein and MANA ABDs...

  3. Surface modification agents for lithium batteries

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Zonghai; Amine, Khalil; Belharouak, Ilias

    2017-11-21

    An active material for an electrochemical device wherein a surface of the active material is modified by a surface modification agent, wherein the surface modification agent is an organometallic compound.

  4. 2APL: a practical agent programming language

    OpenAIRE

    Dastani, M.M.

    2008-01-01

    This article presents a BDI-based agent-oriented programming language, called 2APL (A Practical Agent Programming Language). This programming language facilitates the implementation ofmulti-agent systems consisting of individual agents thatmay share and access external environments. It realizes an effective integration of declarative and imperative style programming by introducing and integrating declarative beliefs and goals with events and plans. It also provides practical programming const...

  5. An overview of agents in knowledge management

    OpenAIRE

    Dignum, M.V.

    2006-01-01

    Current developments in Knowledge Management concern the sharing and usage of knowledge in dynamic environments. The need for systems that both react to and anticipate the needs and expectations of users calls for flexible and adaptable development and implementation frameworks. These are exactly the characteristics that identify software agents and agent societies, which make natural the application of the agent paradigm in KM. This paper attempts to identify both the advantages of agents fo...

  6. Honey - A Novel Antidiabetic Agent

    Science.gov (United States)

    Erejuwa, Omotayo O.; Sulaiman, Siti A.; Wahab, Mohd S. Ab

    2012-01-01

    Diabetes mellitus remains a burden worldwide in spite of the availability of numerous antidiabetic drugs. Honey is a natural substance produced by bees from nectar. Several evidence-based health benefits have been ascribed to honey in the recent years. In this review article, we highlight findings which demonstrate the beneficial or potential effects of honey in the gastrointestinal tract (GIT), on the gut microbiota, in the liver, in the pancreas and how these effects could improve glycemic control and metabolic derangements. In healthy subjects or patients with impaired glucose tolerance or diabetes mellitus, various studies revealed that honey reduced blood glucose or was more tolerable than most common sugars or sweeteners. Pre-clinical studies provided more convincing evidence in support of honey as a potential antidiabetic agent than clinical studies did. The not-too-impressive clinical data could mainly be attributed to poor study designs or due to the fact that the clinical studies were preliminary. Based on the key constituents of honey, the possible mechanisms of action of antidiabetic effect of honey are proposed. The paper also highlights the potential impacts and future perspectives on the use of honey as an antidiabetic agent. It makes recommendations for further clinical studies on the potential antidiabetic effect of honey. This review provides insight on the potential use of honey, especially as a complementary agent, in the management of diabetes mellitus. Hence, it is very important to have well-designed, randomized controlled clinical trials that investigate the reproducibility (or otherwise) of these experimental data in diabetic human subjects. PMID:22811614

  7. Agent based energy management systems

    Energy Technology Data Exchange (ETDEWEB)

    Wolter, Martin

    2012-07-01

    In liberalized, regulated energy markets, the different participants - namely producers and consumers of energy, transmission and distribution system operators as well as regulatory authorities - have partly divergent and partly convergent interests. Loads, power plants and grid operators try to maximize their own benefit in this highly complex environment accepting to act detrimentally to others. Although the relationship between the participants is mostly competitive, there are some fundamental shared interests, e.g. voltage stability, a constant system frequency or efficient energy production, transmission and distribution, which are endangered e.g. by increased injection of volatile sources in low and medium voltage grids, displacement of stabilizing bulk generation and the slowly progressing extension of the electric grid. There is a global consensus, that the resulting challenges can efficiently be faced using information and communication technologies to coordinate grid utilization and operation. The basic idea is to benefit from unused reserves by participating in deployment of system services e.g. reactive power supply to keep the voltage within certain bounds. The coordination can best be done by the grid operator. All activities of that kind are summarized under the umbrella term ''Smart Grid''. To simultaneously model the behavior and interests of different types of market participants and their convergent and divergent interests, multi-agent systems are used. They offer a perfectly fitting framework for this sort of game theory and can easily be adapted to all kinds of new challenges of electricity markets. In this work, multi-agent systems are used to either cooperatively or competitively solve problems in distribution and transmission systems. Therefore, conventional algorithms have to be modified to converge into multiple local optima using only small pieces of the entire system information. It is clearly stated, that personal

  8. Anticancer agents from marine sponges.

    Science.gov (United States)

    Ye, Jianjun; Zhou, Feng; Al-Kareef, Ammar M Q; Wang, Hong

    2015-01-01

    Marine sponges are currently one of the richest sources of anticancer active compounds found in the marine ecosystems. More than 5300 different known metabolites are from sponges and their associated microorganisms. To survive in the complicated marine environment, most of the sponge species have evolved chemical means to defend against predation. Such chemical adaptation produces many biologically active secondary metabolites including anticancer agents. This review highlights novel secondary metabolites in sponges which inhibited diverse cancer species in the recent 5 years. These natural products of marine sponges are categorized based on various chemical characteristics.

  9. Social Robots as Persuasive Agents

    DEFF Research Database (Denmark)

    Vlachos, Evgenios; Schärfe, Henrik

    2014-01-01

    Robots are more and more used in a social context, and in this paper we try to formulate a research agenda concerning ethical issues around social HRI in order to be prepared for future scenarios where robots may be a naturally integrated part of human society. We outline different paradigms to d...... to describe the role of social robots in communication processes with humans, and connect HRI with the topic of persuasive technology in health care, to critically reflect the potential benefits of using social robots as persuasive agents....

  10. Protein binding of psychotropic agents

    International Nuclear Information System (INIS)

    Hassan, H.A.

    1990-01-01

    Based upon fluorescence measurements, protein binding of some psychotropic agents (chlorpromazine, promethazine, and trifluoperazine) to human IgG and HSA was studied in aqueous cacodylate buffer, PH7. The interaction parameters determined from emission quenching of the proteins. The interaction parameters determined include the equilibrium constant (K), calculated from equations derived by Borazan and coworkers, the number of binding sites (n) available to the monomer molecules on a single protein molecule. The results revealed a high level of affinity, as reflected by high values of K, and the existence of specific binding sites, since a limited number of n values are obtained. 39 tabs.; 37 figs.; 83 refs

  11. Multi agent gathering waste system

    Directory of Open Access Journals (Sweden)

    Álvaro LOZANO MURCIEGO

    2016-07-01

    Full Text Available Along this paper, we present a new multi agent-based system to gather waste on cities and villages. We have developed a low cost wireless sensor prototype to measure the volume level of the containers. Furthermore a route system is developed to optimize the routes of the trucks and a mobile application has been developed to help drivers in their working days. In order to evaluate and validate the proposed system a practical case study in a real city environment is modeled using open data available and with the purpose of identifying limitations of the system.

  12. Diarrhea caused by circulating agents.

    Science.gov (United States)

    Fabian, Elisabeth; Kump, Patrizia; Krejs, Guenter J

    2012-09-01

    Circulating agents cause intestinal secretion or changes in motility with decreased intestinal transit time, resulting in secretory-type diarrhea. Secretory diarrhea as opposed to osmotic diarrhea is characterized by large-volume, watery stools, often more than 1 L per day; by persistence of diarrhea when patients fast; and by the fact that on analysis of stool-water, measured osmolarity is identical to that calculated from the electrolytes present. Although sodium plays the main role in water and electrolyte absorption, chloride is the major ion involved in secretion. Copyright © 2012 Elsevier Inc. All rights reserved.

  13. A principal-agent Model of corruption

    NARCIS (Netherlands)

    Groenendijk, Nico

    1997-01-01

    One of the new avenues in the study of political corruption is that of neo-institutional economics, of which the principal-agent theory is a part. In this article a principal-agent model of corruption is presented, in which there are two principals (one of which is corrupting), and one agent (who is

  14. Do pedagogical agents enhance software training?

    NARCIS (Netherlands)

    van der Meij, Hans

    2013-01-01

    This study investigates whether a tutorial for software training can be enhanced by adding a pedagogical agent, and whether the type of agent matters (i.e., cognitive, motivational, or mixed). The cognitive agent was designed to stimulate students to process their experiences actively. The

  15. Animated BDP agents in virtual environments

    NARCIS (Netherlands)

    Nijholt, Antinus; Egges, A.; op den Akker, Hendrikus J.A.; Zwiers, Jakob; Krose, B.; de Rijke, M.; Schreiber, G.; van Someren, M.

    2001-01-01

    We introduce a Believes, Desires and Plans (BDP) agent that acts in a virtual environment using multi-modal interaction with the user. The environment is our virtual theatre environment. In this environment different agents have been introduced. In order to obtain a more uniform framework for agent

  16. Group Formation Among Decentralized Autonomous Agents

    NARCIS (Netherlands)

    Ogston, E.F.Y.L.; van Steen, M.R.; Brazier, F.M.

    2004-01-01

    This paper examines a method of clustering within a fully decentralized multi-agent system. Our goal is to group agents with similar objectives or data, as is done in traditional clustering. However, we add the additional constraint that agents must remain in place on a network, instead of first

  17. Individualism and Collectivism in Trade Agents

    NARCIS (Netherlands)

    Hofstede, G.J.; Jonker, C.M.; Verwaart, D.

    2008-01-01

    Agent-Based Modeling can contribute to the understanding of international trade processes. Models for the effects of culture and cultural differences on agent behavior are required for realistic agent-based simulation of international trade. This paper makes a step toward modeling of culture in

  18. A Framework for Organization-Aware Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Dignum, Virginia; Villadsen, Jørgen

    2016-01-01

    This short paper introduces and summarizes the AORTA reasoning framework that can be integrated into BDI-agents to enable organizational decision-making. This work has recently been published in the Journal of Autonomous Agents and Multi-Agent Systems (JAAMAS), as [3]....

  19. Radioactive scanning agents with hydroquinone stabilizer

    International Nuclear Information System (INIS)

    Whitehouse, H.S.

    1982-01-01

    Stable compositions useful as technetium 99m-based scintigraphic agents comprise hydroquinone in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (sup(99m)TcOsub(4)sup(-)) solution. The compositions are especially useful in combination with a phosphate or phosphonate material which carries the radionuclide to bone, thus providing a skeletal imaging agent

  20. On Programming Organization-Aware Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt

    2013-01-01

    Since it is difficult (or even impossible) to assume anything about the agents’ behavior and goals in an open multi-agent system, it is often suggested that an organization is imposed upon the agents, whichhich, by abstracting away from the agents, specifies boundaries and objectives that the age...

  1. Cooperative heuristic multi-agent planning

    NARCIS (Netherlands)

    De Weerdt, M.M.; Tonino, J.F.M.; Witteveen, C.

    2001-01-01

    In this paper we will use the framework to study cooperative heuristic multi-agent planning. During the construction of their plans, the agents use a heuristic function inspired by the FF planner (l3l). At any time in the process of planning the agents may exchange available resources, or they may

  2. IRANIAN MEDICINAL PLANTS AS ANTIMICROBIAL AGENTS

    OpenAIRE

    Mohaddese Mahboubi

    2013-01-01

    Resistance of human and food spoilage pathogens to antimicrobial agents and the side effects of chemical agents or preservative for human is caused for finding natural new antimicrobial agents, especially among the medicinal plants. This review introduces the methods that are used for antimicrobial evaluations and synergistic activities and the antimicrobial potential of some Iranian medicinal plants.

  3. Embedded Automation in Human-Agent Environment

    CERN Document Server

    Tweedale, Jeffrey W

    2012-01-01

    This research book proposes a general conceptual framework for the development of automation in human-agents environments that will allow human- agent teams to work effectively and efficiently. We examine various schemes to implement artificial intelligence techniques in agents.  The text is directed to the scientists, application engineers, professors and students of all disciplines, interested in the agency methodology and applications.

  4. Mobile Agents in Networking and Distributed Computing

    CERN Document Server

    Cao, Jiannong

    2012-01-01

    The book focuses on mobile agents, which are computer programs that can autonomously migrate between network sites. This text introduces the concepts and principles of mobile agents, provides an overview of mobile agent technology, and focuses on applications in networking and distributed computing.

  5. Agent modelling in METATEM and DESIRE

    NARCIS (Netherlands)

    Mulder, Marco; Treur, Jan; Fisher, Michael

    1998-01-01

    In spite of the rapid spread of agent technology, there is, as yet, little evidence of an engineering approach to the development of multi-agent systems. For example, both development methods and verification techniques for multi-agent systems are rare. In this paper, we describe a case study aimed

  6. Using Intelligent Agents To Assist Educators.

    Science.gov (United States)

    Knode, Steve; Knode, Jon-David W.

    This paper begins with background on intelligent agents (software programs built to perform certain specific tasks for the user). A taxonomy that categorizes intelligent agents by the degree of intelligence embedded in the software is presented. Applications of today's intelligent agents are discussed, including specific examples of the following:…

  7. Information brokering agents in intelligent Websites

    NARCIS (Netherlands)

    Jonker, Catholijn M.; Treur, J.

    1999-01-01

    In this paper a generic information broker agent for intelligent Websites is introduced. The agent architecture has been designed using the compositional development method for multi-agent systems Desire. The use of the architecture is illustrated in an Electronic Commerce application for a

  8. Modelling an Agent's Mind and Matter

    NARCIS (Netherlands)

    Jonker, C.M.; Treur, J.; Boman, M.

    1997-01-01

    In agent models often it is assumed that the agent maintains internal representations of the material world (e.g., its beliefs). An overall model of the agent and the material world necessarily incorporates sub-models for physical simulation and symbolic simulation, and a formalisation of the

  9. Making Agents Gaze Naturally. Does it work?

    NARCIS (Netherlands)

    van Es, Ivo; De Marsico, M.; Levialdi, S.; Heylen, Dirk K.J.; Panizzi, E.; van Dijk, Elisabeth M.A.G.; Nijholt, Antinus

    2002-01-01

    We investigated the effects of varying eye gaze behavior of an embodied conversational agent on the quality of human-agent dialogues. In an experiment we compared three versions of an agent: one with gaze behavior that is typically found to occur in human-human dialogues, one with gaze that is fixed

  10. Effectiveness testing of spill-treating agents

    International Nuclear Information System (INIS)

    Fingas, M.F.; Stoodley, R.; Laroche, N.

    1990-01-01

    Laboratory effectiveness tests are described for four classes of spill-treating agents: solidifiers, demulsifying agents, surface-washing agents and dispersants. Many treating agents in these four categories have been tested for effectiveness and the results are presented. Solidifiers or gelling agents solidify oil, requiring a large amount of agent to solidify oil-ranging between 16% by weight, to over 200%. Emulsion breakers prevent or reverse the formation of water-in-oil emulsions. A newly-developed effectiveness test shows that only one product is highly effective; however, many products will work, but require large amounts of spill-treating agent. Surfactant--containing materials are of two types, surface-washing agents and dispersants. Testing has shown that an agent that is a good dispersant is conversely a poor surface-washing agent, and vice versa. Tests of surface-washing agents show that only a few agents have effectiveness of 25-40%, where this effectiveness is the percentage of heavy oil removed from a test surface. Results using the 'swirling flask' test for dispersant effectiveness are reported. Heavy oils show effectiveness values of about 1%, medium crudes of about 10%, light crude oils of about 30% and very light oils of about 90%. (author)

  11. Mobile agent location in distributed environments

    Science.gov (United States)

    Fountoukis, S. G.; Argyropoulos, I. P.

    2012-12-01

    An agent is a small program acting on behalf of a user or an application which plays the role of a user. Artificial intelligence can be encapsulated in agents so that they can be capable of both behaving autonomously and showing an elementary decision ability regarding movement and some specific actions. Therefore they are often called autonomous mobile agents. In a distributed system, they can move themselves from one processing node to another through the interconnecting network infrastructure. Their purpose is to collect useful information and to carry it back to their user. Also, agents are used to start, monitor and stop processes running on the individual interconnected processing nodes of computer cluster systems. An agent has a unique id to discriminate itself from other agents and a current position. The position can be expressed as the address of the processing node which currently hosts the agent. Very often, it is necessary for a user, a processing node or another agent to know the current position of an agent in a distributed system. Several procedures and algorithms have been proposed for the purpose of position location of mobile agents. The most basic of all employs a fixed computing node, which acts as agent position repository, receiving messages from all the moving agents and keeping records of their current positions. The fixed node, responds to position queries and informs users, other nodes and other agents about the position of an agent. Herein, a model is proposed that considers pairs and triples of agents instead of single ones. A location method, which is investigated in this paper, attempts to exploit this model.

  12. Nonsteroid anti-inflammatory agents.

    Science.gov (United States)

    Paulus, H E; Whitehouse, M W

    1973-01-01

    Nonsteroidal antiinflammatory agents (NSAID) are reviewed. Aspirin, indomethacin, and salicylate have all been shown to interfere or prevent the synthesis of prostaglandins (PGs), a main tissue inflammatory substance. However, an exception to the correlation of PG-synthetase inhibition with antiinflammatory activity has been noted with certain arylacetic acids. Studies on the role of lysosomes in the inflammation are criticized in this review, mainly because of improper understanding of the role of lysosomes in a physiological system. Since lysosomes are not a specific body, but an activator, attempts to isolate lysosomes to study functions are doomed to failure; i.e., a lysosome has no definition without the rest of its self-regulating system. NSAIDs work in 2 main ways; either via antiaggregation or antiinflammation. This may result in drug interactions between various types of NSAIDs. For example, simultaneous administration of aspirin with indomethacine did not produce an additive effect; rather they produced no effect in the rat paw edema test dissimilar to the action of either drug separately. However, hydrocortisone combined with another NSAID enhanced its antiinflammatory effects. Albumin binding theories of NSAID mechanism of action state that drugs are active only when albumin-bound because it has displaced tryptophane, or urate, or some other normally bound substance. The only way to discover an efficient antiinflammatory agent is to obviate the need for it by discovering the actual mechanism of inflammation, for when specific anti-etiologic therapy is developed, the need for treatment with NSAIDs is irrelevant.

  13. A Review of Luting Agents

    Directory of Open Access Journals (Sweden)

    Cornelis H. Pameijer

    2012-01-01

    Full Text Available Due to the availability of a large number of luting agents (dental cements proper selection can be a daunting task and is usually based on a practitioner’s reliance on experience and preference and less on in depth knowledge of materials that are used for the restoration and luting agent properties. This review aims at presenting an overview of current cements and discusses physical properties, biocompatibility and other properties that make a particular cement the preferred choice depending on the clinical indication. Tables are provided that outline the different properties of the generic classification of cements. It should be noted that no recommendations are made to use a particular commercial cement for a hypothetical clinical situation. The choice is solely the responsibility of the practitioner. The appendix is intended as a guide for the practitioner towards a recommended choice under commonly encountered clinical scenarios. Again, no commercial brands are recommended although the author recognizes that some have better properties than others. Please note that this flowchart strictly presents the author’s opinion and is based on research, clinical experience and the literature.

  14. Animal venoms as antimicrobial agents.

    Science.gov (United States)

    Perumal Samy, Ramar; Stiles, Bradley G; Franco, Octavio L; Sethi, Gautam; Lim, Lina H K

    2017-06-15

    Hospitals are breeding grounds for many life-threatening bacteria worldwide. Clinically associated gram-positive bacteria such as Staphylococcus aureus/methicillin-resistant S. aureus and many others increase the risk of severe mortality and morbidity. The failure of antibiotics to kill various pathogens due to bacterial resistance highlights the urgent need to develop novel, potent, and less toxic agents from natural sources against various infectious agents. Currently, several promising classes of natural molecules from snake (terrestrial and sea), scorpion, spider, honey bee and wasp venoms hold promise as rich sources of chemotherapeutics against infectious pathogens. Interestingly, snake venom-derived synthetic peptide/snake cathelicidin not only has potent antimicrobial and wound-repair activity but is highly stable and safe. Such molecules are promising candidates for novel venom-based drugs against S. aureus infections. The structure of animal venom proteins/peptides (cysteine rich) consists of hydrophobic α-helices or β-sheets that produce lethal pores and membrane-damaging effects on bacteria. All these antimicrobial peptides are under early experimental or pre-clinical stages of development. It is therefore important to employ novel tools for the design and the development of new antibiotics from the untapped animal venoms of snake, scorpion, and spider for treating resistant pathogens. To date, snail venom toxins have shown little antibiotic potency against human pathogens. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Ruthenium complexes as antimicrobial agents.

    Science.gov (United States)

    Li, Fangfei; Collins, J Grant; Keene, F Richard

    2015-04-21

    One of the major advances in medical science has been the development of antimicrobials; however, a consequence of their widespread use has been the emergence of drug-resistant populations of microorganisms. There is clearly a need for the development of new antimicrobials--but more importantly, there is the need for the development of new classes of antimicrobials, rather than drugs based upon analogues of known scaffolds. Due to the success of the platinum anticancer agents, there has been considerable interest in the development of therapeutic agents based upon other transition metals--and in particular ruthenium(II/III) complexes, due to their well known interaction with DNA. There have been many studies of the anticancer properties and cellular localisation of a range of ruthenium complexes in eukaryotic cells over the last decade. However, only very recently has there been significant interest in their antimicrobial properties. This review highlights the types of ruthenium complexes that have exhibited significant antimicrobial activity and discusses the relationship between chemical structure and biological processing--including site(s) of intracellular accumulation--of the ruthenium complexes in both bacterial and eukaryotic cells.

  16. Surfactants as blackbird stressing agents

    Science.gov (United States)

    Lefebvre, P.W.; Seubert, J.L.

    1970-01-01

    Applications of wetting-agent solutions produce mortality in birds. The exact cause of death is undetermined but it is believed that destruction of the insulating qualities of the plumage permits ambient cold temperatures and evaporation to lower the body temperature to a lethal level. The original concept of using these materials as bird-control tools was developed in 1958 at the Patuxent Wildlife Research Center, Bureau of Sport Fisheries and Wildlife Laurel, Maryland. Early field trials by personnel of the Division of Wildlife Services and the Denver Wildlife Research Center indicated that ground-application techniques had promise but limitations of the equipment precluded successful large-scale roost treatments. In 1966, Patuxent Center personnel began using tanker-type aircraft to evaluate high-volume aerial applications of wetting agents. The success of these tests led to the use of small aircraft to make low-volume, high-concentration aerial applications just prior to expected rainfall. Recent trials of the low-volume method show that, with some limitations, it is effective, inexpensive, and safe to the environment. Current research emphasizes the screening of new candidate materials for efficacy, biodegradability, and toxicity to plants and non-target animals, as well as basic investigations of the avian physiological mechanisms involved. Field trials to develop more effective application techniques will continue.

  17. Building Multi-Agent Systems Using Jason

    DEFF Research Database (Denmark)

    Boss, Niklas Skamriis; Jensen, Andreas Schmidt; Villadsen, Jørgen

    2010-01-01

    We provide a detailed description of the Jason-DTU system, including the used methodology, tools as well as team strategy. We also discuss the experience gathered in the contest. In spring 2009 the course “Artificial Intelligence and Multi- Agent Systems” was held for the first time...... on the Technical University of Denmark (DTU). A part of this course was a short introduction to the multi-agent framework Jason, which is an interpreter for AgentSpeak, an agent-oriented programming language. As the final project in this course a solution to the Multi-Agent Programming Contest from 2007, the Gold...

  18. Reversal agents in anaesthesia and critical care

    Directory of Open Access Journals (Sweden)

    Nibedita Pani

    2015-01-01

    Full Text Available Despite the advent of short and ultra-short acting drugs, an in-depth knowledge of the reversal agents used is a necessity for any anaesthesiologist. Reversal agents are defined as any drug used to reverse the effects of anaesthetics, narcotics or potentially toxic agents. The controversy on the routine reversal of neuromuscular blockade still exists. The advent of newer reversal agents like sugammadex have made the use of steroidal neuromuscular blockers like rocuronium feasible in rapid sequence induction situations. We made a review of the older reversal agents and those still under investigation for drugs that are regularly used in our anaesthesia practice.

  19. Variations on agent-oriented programming

    Directory of Open Access Journals (Sweden)

    Dalia Baziukė

    2017-12-01

    Full Text Available Occurrence of the agent paradigm and its further applications have stimulated the emergence of new concepts and methodologies in computer science. Today terms like multi-agent system, agent-oriented methodology, and agent-oriented programming (AOP are widely used. The aim of this paper is to clarify the validity of usage of the terms AOP and AOP language. This is disclosed in two phases of an analysis process. Determining to which concepts, terms like agent, programming, object-oriented analysis and design, object-oriented programming, and agent-oriented analysis and design correspond is accomplished in the first phase. Analysis of several known agent system engineering methodologies in terms of key concepts used, final resulting artifacts, and their relationship with known programming paradigms and modern tools for agent system development is performed in the second phase. The research shows that in most cases in the final phase of agent system design and in the coding stage, the main artifact is an object, defined according to the rules of the object-oriented paradigm. Hence, we say that the computing society still does not have AOP owing to the lack of an AOP language. Thus, the term AOP is very often incorrectly assigned to agent system development frameworks that in most cases, transform agents into objects.DOI: 10.15181/csat.v5i1.1361

  20. Introduction to Agent Mining Interaction and Integration

    Science.gov (United States)

    Cao, Longbing

    In recent years, more and more researchers have been involved in research on both agent technology and data mining. A clear disciplinary effort has been activated toward removing the boundary between them, that is the interaction and integration between agent technology and data mining. We refer this to agent mining as a new area. The marriage of agents and data mining is driven by challenges faced by both communities, and the need of developing more advanced intelligence, information processing and systems. This chapter presents an overall picture of agent mining from the perspective of positioning it as an emerging area. We summarize the main driving forces, complementary essence, disciplinary framework, applications, case studies, and trends and directions, as well as brief observation on agent-driven data mining, data mining-driven agents, and mutual issues in agent mining. Arguably, we draw the following conclusions: (1) agent mining emerges as a new area in the scientific family, (2) both agent technology and data mining can greatly benefit from agent mining, (3) it is very promising to result in additional advancement in intelligent information processing and systems. However, as a new open area, there are many issues waiting for research and development from theoretical, technological and practical perspectives.

  1. A SURVEY OF THE PROPERTIES OF AGENTS

    Directory of Open Access Journals (Sweden)

    Kornelije Rabuzin

    2006-06-01

    Full Text Available In the past decade agent systems were considered to be as one of the major fields of study in Artificial Intelligence (AI field. Many different definitions of agents were presented and several different approaches describing agency can be distinguished. While some authors have tried to define “what” an agent really is, others have tried to identify agents by means of properties which they should possess. Most authors agree on these properties (at least basic set of properties which are intrinsic to agents. Since agent's definitions are not consistent, we are going to give an overview and list the properties intrinsic to an agent. Many different adjectives were attached to the term agent as well and many different kinds of agents and different architectures emerged too. The aim of this paper it go give an overview of what was going on in the field while taking into consideration main streams and projects. We will also present some guidelines important when modelling agent systems and say something about security issues. Also, some existing problems which restrict the wider usage of agents will be mentioned too.

  2. A Framework for Organization-Aware Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Dignum, Virginia; Villadsen, Jørgen

    2017-01-01

    Open systems are characterized by the presence of a diversity of heterogeneous and autonomous agents that act according to private goals. Organizations, such as those used in real-life to structure human activities such as task allocation, coordination and supervision, can regulate the agents...... boundaries and work towards the objectives of the organization. In this paper, we present the AORTA reasoning framework and show how it can be integrated into typical BDI-agents. We provide operational semantics that enables agents to make organizational decisions in order to coordinate and cooperate without...... explicit coordination mechanisms within the agents. The organizational model is independent of that of the agents, and the approach is not tied to a specific organizational model, but uses an organizational metamodel. We show how AORTA helps agents work together in a system with an organization...

  3. An Agent Framework of Tourism Recommender System

    Directory of Open Access Journals (Sweden)

    Jia Zhi Yang

    2016-01-01

    Full Text Available This paper proposes the development of an Agent framework for tourism recommender system. The recommender system can be featured as an online web application which is capable of generating a personalized list of preference attractions for tourists. Traditional technologies of classical recommender system application domains, such as collaborative filtering, content-based filtering and content-based filtering are effectively adopted in the framework. In the framework they are constructed as Agents that can generate recommendations respectively. Recommender Agent can generate recommender information by integrating the recommendations of Content-based Agent, collaborative filtering-based Agent and constraint-based Agent. In order to make the performance more effective, linear combination method of data fusion is applied. User interface is provided by the tourist Agent in form of webpages and mobile app.

  4. Multi-agent for manufacturing systems optimization

    Science.gov (United States)

    Ciortea, E. M.; Tulbure, A.; Huţanu, C.-tin

    2016-08-01

    The paper is meant to be a dynamic approach to optimize manufacturing systems based on multi-agent systems. Multi-agent systems are semiautonomous decision makers and cooperate to optimize the manufacturing process. Increasing production the capacity is achieved by developing, implementing efficient and effective systems from control based on current manufacturing process. The model multi-agent proposed in this paper is based on communication between agents who, based on their mechanisms drive to autonomous decision making. Methods based on multi-agent programming are applied between flexible manufacturing processes and cooperation with agents. Based on multi-agent technology and architecture of intelligent manufacturing can lead to development of strategies for control and optimization of scheduled production resulting from the simulation.

  5. 10th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Pérez, Javier; Golinska, Paulina; Giroux, Sylvain; Corchuelo, Rafael; Trends in Practical Applications of Agents and Multiagent Systems

    2012-01-01

    PAAMS, the International Conference on Practical Applications of Agents and Multi-Agent Systems is an evolution of the International Workshop on Practical Applications of Agents and Multi-Agent Systems. PAAMS is an international yearly tribune to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development of Agents and Multi-Agent Systems.   This volume presents the papers that have been accepted for the 2012 in the workshops: Workshop on Agents for Ambient Assisted Living, Workshop on Agent-Based Solutions for Manufacturing and Supply Chain and Workshop on Agents and Multi-agent systems for Enterprise Integration.

  6. Survey of agent for intelligent information retrieval; Chiteki kensaku no tame no agent no chosa

    Energy Technology Data Exchange (ETDEWEB)

    Yazawa, T. [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1996-09-01

    Development of agent systems has been surveyed, to classify and arrange characteristic functions of the agents, and to grasp the realization situation of these agents in their development. In addition, prospective functions of information retrieval systems using the agents at maximum and functions to be developed among these in the future are clarified. The agents are characterized by the expression function, communication function, planning function, adaptive function, and learning function. The agents are desired to be classified into interface agents whose works are to respond to individual workers, coordinator agents which conduct works with high pervasion, such as assignment of works and their control, and task agents which conduct specialized works for individual examples. Thus, design and configuration of the agent system, and improvement and expansion of system functions can be effectively and easily conducted. 52 refs., 5 figs., 3 tabs.

  7. Bioprotective agents in safety control

    Directory of Open Access Journals (Sweden)

    Dimitrijević-Branković Suzana I.

    2003-01-01

    Full Text Available Food poisoning is the one of the main health hazards even today. More than 200 known diseases are transmitted through food. The causes of foodborne illness include viruses, bacteria, parasites, toxins, metals, and prions and the symptoms of foodborne illness range from mild gastroenteritis to life-threatening neurological, hepatic and renal syndromes.The prevention of food poisonings represents very serious task for food manufacturers. Beside food control according to the concept "from the farm to the table" there is increased need for the development of new technology for longer shelf lifes of food. Food fermented by lactic acid bacteria (LAB and traditionally considered to be safe. There are many substances produced by LAB that affect the shelf life of fermented food, by active suppression of poisoning microorganisms growth. Because of that, the LAB is recently considered as bioprotective agents that have important role in food safety.

  8. Il libro agente della socializzazione

    Directory of Open Access Journals (Sweden)

    Daniela Sideri

    2017-06-01

    Full Text Available Il saggio indaga il ruolo del libro come agente di socializzazione, con particolare riferimento al pubblico dei lettori ragazzi e bambini e alle specifiche funzioni formative della “lettura della letteratura” in età pre-scolare e scolare fino ai 14 anni. La ricerca di matrice socio-culturale si è occupata per lo più del libro in qualità di prodotto eminentemente sociale (sociologia della letteratura, contenitore di testi significanti (semiotica, e bene di consumo dell’industria culturale (cultural studies: lo studio proposto richiama le conclusioni fondamentali di decenni di studi intorno al libro, con l’intento di rintracciare i criteri adeguati (tema, target, identità visiva, funzione pratica e utopica a guidare una classificazione dei generi 0-14 che evidenzi il valore socializzante di ciascuno, proponendo così una originale tipologia, che giustifica l’inserimento del libro tra quelle definite “agenzie testuali” della socializzazione.

  9. Host modulation by therapeutic agents

    Directory of Open Access Journals (Sweden)

    Sugumari Elavarasu

    2012-01-01

    Full Text Available Periodontal disease susceptible group present advanced periodontal breakdown even though they achieve a high standard of oral hygiene. Various destructive enzymes and inflammatory mediators are involved in destruction. These are elevated in case of periodontal destruction. Host modulation aims at bringing these enzymes and mediators to normal level. Doxycycline, nonsteroidal anti-inflammatory drugs (NSAIDs, bisphosphonates, nitrous oxide (NO synthase inhibitors, recombinant human interleukin-11 (rhIL-11, omega-3 fatty acid, mouse anti-human interleukin-6 receptor antibody (MRA, mitogen-activated protein kinase (MAPK inhibitors, nuclear factor-kappa B (NF-kb inhibitors, osteoprotegerin, and tumor necrosis factor antagonist (TNF-α are some of the therapeutic agents that have host modulation properties.

  10. DNA minor groove alkylating agents.

    Science.gov (United States)

    Denny, W A

    2001-04-01

    Recent work on a number of different classes of anticancer agents that alkylate DNA in the minor groove is reviewed. There has been much work with nitrogen mustards, where attachment of the mustard unit to carrier molecules can change the normal patterns of both regio- and sequence-selectivity, from reaction primarily at most guanine N7 sites in the major groove to a few adenine N3 sites at the 3'-end of poly(A/T) sequences in the minor groove. Carrier molecules discussed for mustards are intercalators, polypyrroles, polyimidazoles, bis(benzimidazoles), polybenzamides and anilinoquinolinium salts. In contrast, similar targeting of pyrrolizidine alkylators by a variety of carriers has little effect of their patterns of alkylation (at the 2-amino group of guanine). Recent work on the pyrrolobenzodiazepine and cyclopropaindolone classes of natural product minor groove binders is also reviewed.

  11. Blasting agents and initiation systems

    Energy Technology Data Exchange (ETDEWEB)

    Fiscor, S.

    2000-01-01

    Although blasting differs between and within each industry, as a whole, the mines and quarries are making a shift from a purely ammonium nitrate/fuel oil (ANFO) mixture to a blend of emulsion and ANFO on a straight emulsion. Non-electric (shock tube) initiation systems have provided a viable alternative to the electric detonator (blasting cap). Explosives manufacturers are seeing their roles changes to being blasting contractors or consultants rather than just suppliers. The article discusses these trends and gives examples of typical blasting techniques and amounts of blasting agent used at large USA surface coal mines. Electric caps are still used in blasting underground coal. The Ensign Bickford Co. (EBCo) is developing electronic detonators and has been field testing an electronic initiator, the DIGIDET detonator, for the last four years. When commercially available, electronic detonators will be accurate but will come with a hefty price tag. 2 photos.

  12. An Important Chemical Weapon Group: Nerve Agents

    Directory of Open Access Journals (Sweden)

    Hakan Yaren

    2007-12-01

    Full Text Available As a result of developing modern chemistry, nerve agents, which are one of the most important group of efficient chemical warfare agents, were developed just before Second World War. They generate toxic and clinical effects via inhibiting acetylcholinesterase irreversibly and causing excessive amounts of acetylcholine at cholinergic synapses in the body. Clinical symptoms are occurred as a result of affected muscarinic (stimulation of secretuar glands, miosis, breathing problems etc., nicotinic (stimulation of skeletal muscles, paralyse, tremors etc. and central nerve system (convulsions, loss of consciousness, coma etc. areas. In case of a nerve agent exposure, treatment includes the steps of ventilation, decontamination, antidotal treatment (atropine, oximes, diazepam and pyridostigmine bromide and supportive theraphy. Because of arising possibility of using chemical warfare agents due to current conjuncture of the world, medical staff should know about nerve agents, their effects and how to treat the casualties exposured to nerve agents. [TAF Prev Med Bull 2007; 6(6.000: 491-500

  13. An Important Chemical Weapon Group: Nerve Agents

    Directory of Open Access Journals (Sweden)

    Hakan Yaren

    2007-12-01

    Full Text Available As a result of developing modern chemistry, nerve agents, which are one of the most important group of efficient chemical warfare agents, were developed just before Second World War. They generate toxic and clinical effects via inhibiting acetylcholinesterase irreversibly and causing excessive amounts of acetylcholine at cholinergic synapses in the body. Clinical symptoms are occurred as a result of affected muscarinic (stimulation of secretuar glands, miosis, breathing problems etc., nicotinic (stimulation of skeletal muscles, paralyse, tremors etc. and central nerve system (convulsions, loss of consciousness, coma etc. areas. In case of a nerve agent exposure, treatment includes the steps of ventilation, decontamination, antidotal treatment (atropine, oximes, diazepam and pyridostigmine bromide and supportive theraphy. Because of arising possibility of using chemical warfare agents due to current conjuncture of the world, medical staff should know about nerve agents, their effects and how to treat the casualties exposured to nerve agents. [TAF Prev Med Bull. 2007; 6(6: 491-500

  14. Supporting a Learner Community with Software Agents

    Directory of Open Access Journals (Sweden)

    Pierre Tchounikine

    2004-04-01

    Full Text Available This paper describes a multi- agent approach that aims at supporting learners involved in a collective activity. We consider pedagogical situations where students have to explicitly define the articulation of their collective work and then achieve the different tasks they have defined. Our objective is to support these students by taking some of these tasks in charge whilst making them work out such organisation features. For this purpose, we propose to consider that the group of students forms a multi- agent system and to introduce software agents that can achieve some of the tasks within this group. This conducts students to tackle the problem in terms of human and software agent coordination. We present how this approach can be conceptualized and modelled using Engeström’s triangle, how task delegation can be used as a means to enable students to define the software agents’ behaviour and the multi-agent implementation we propose.

  15. Persuasive Conversational Agent with Persuasion Tactics

    Science.gov (United States)

    Narita, Tatsuya; Kitamura, Yasuhiko

    Persuasive conversational agents persuade people to change their attitudes or behaviors through conversation, and are expected to be applied as virtual sales clerks in e-shopping sites. As an approach to create such an agent, we have developed a learning agent with the Wizard of Oz method in which a person called Wizard talks to the user pretending to be the agent. The agent observes the conversations between the Wizard and the user, and learns how to persuade people. In this method, the Wizard has to reply to most of the user's inputs at the beginning, but the burden gradually falls because the agent learns how to reply as the conversation model grows.

  16. Radioiodine: the classic theranostic agent.

    Science.gov (United States)

    Silberstein, Edward B

    2012-05-01

    Radioiodine has the distinction of being the first theranostic agent in our armamentarium. Millennia were required to discover that the agent in orally administered seaweed and its extracts, which had been shown to cure neck swelling due to thyromegaly, was iodine, first demonstrated to be a new element in 1813. Treatment of goiter with iodine began at once, but its prophylactic value to prevent a common form of goiter took another century. After Enrico Fermi produced the first radioiodine, (128)I, in 1934, active experimentation in the United States and France delineated the crucial role of iodine in thyroid metabolism and disease. (130)I and (131)I were first employed to treat thyrotoxicosis by 1941, and thyroid cancer in 1943. After World War II, (131)I became widely available at a reasonable price for diagnostic testing and therapy. The rectilinear scanner of Cassen and Curtis (Science 1949;110:94-95), and a dedicated gamma camera invented by Anger (Nature 1952;170:200-201), finally permitted the diagnostic imaging of thyroid disease, with (131)I again the radioisotope of choice, although there were short-lived attempts to employ (125)I and (132)I for this purpose. (123)I was first produced in 1949 but did not become widely available until about 1982, 10 years after a production technique eliminated high-energy (124)I contamination. I continues to be the radioiodine of choice for the diagnosis of benign thyroid disease, whereas (123)I and (131)I are employed in the staging and detection of functioning thyroid cancer. (124)I, a positron emitter, can produce excellent anatomically correlated images employing positron emission tomography/computed tomography equipment and has the potential to enhance heretofore imperfect dosimetric studies in determining the appropriate administered activity to ablate/treat thyroid cancer. Issues of acceptable measuring error in thyroid cancer dosimetry and the role in (131)I therapy of tumor heterogeneity, tumor hypoxia, and

  17. Inaccessibility in Multi-Agent Systems

    Science.gov (United States)

    2004-03-08

    Mař́ık, D. McFarlane, and P. Valckenaers (eds.): Holonic and Multi-Agent Systems for Manufacturing , No. 2744 in LNAI. Springer-Verlag, Heidelberg. 17...in Multi-Agent Systems 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5d. TASK NUMBER 6. AUTHOR(S) Professor Vladimir Marik 5e. WORK UNIT NUMBER...short term inaccessibility, (3) long term inaccessibility, and (4) testing and validation. 15. SUBJECT TERMS EOARD, Multi Agent Systems , Behavior

  18. Different Views of Software Agent Paradigm

    OpenAIRE

    Anand Kumar Pandey; Rashmi Pandey

    2012-01-01

    Agent modelling in software engineering is a relatively young area, and there are, as yet, no standard methodologies, development tools, or software architectures. Although our work is emphasized on to represent the agent specifications using different views, they are not oriented for software engineering in terms of providing a modeling notation that directly supports software development. There are, however, some software frameworks using different views of software agents, that are beginni...

  19. Running agent-based simulations. Unternehmensmodell / Computersimulation.

    OpenAIRE

    Meyer, David; Karatzoglou, Alexandros; Buchta, Christian; Leisch, Friedrich; Hornik, Kurt

    2001-01-01

    When running agent-based simulations using ready-made components, one usually faces heterogenity problems both for the agents' implementation and for the underlying platform. To circumvent these kind of hindrances, we introduce a wrapper technique for mapping the functionality of agents living in an interpreter-based environment to a standardized CORBA interface, thus facilitating the task for any control mechanism (like a simulation manager) which just will need to handle one set of commands...

  20. Glutamic acid as anticancer agent: An overview

    OpenAIRE

    Dutta, Satyajit; Ray, Supratim; Nagarajan, K.

    2013-01-01

    The objective of the article is to highlight various roles of glutamic acid like endogenic anticancer agent, conjugates to anticancer agents, and derivatives of glutamic acid as possible anticancer agents. Besides these emphases are given especially for two endogenous derivatives of glutamic acid such as glutamine and glutamate. Glutamine is a derivative of glutamic acid and is formed in the body from glutamic acid and ammonia in an energy requiring reaction catalyzed by glutamine synthase. I...

  1. Rule Value Reinforcement Learning for Cognitive Agents

    OpenAIRE

    Child, C. H. T.; Stathis, K.

    2006-01-01

    RVRL (Rule Value Reinforcement Learning) is a new algorithm which extends an existing learning framework that models the environment of a situated agent using a probabilistic rule representation. The algorithm attaches values to learned rules by adapting reinforcement learning. Structure captured by the rules is used to form a policy. The resulting rule values represent the utility of taking an action if the rule`s conditions are present in the agent`s current percept. Advantages of the new f...

  2. Intelligent Agents in E-Commerce

    Directory of Open Access Journals (Sweden)

    Valentin LITOIU

    2006-01-01

    Full Text Available This paper emphasizes the importance of intelligent agents in e-commerce, with a particular focus on the B2C and B2B context. From the consumer buying behaviour perspective, agents can be used to assist the following stages: need identification, product brokering, buyer coalition formation, merchant brokering and negotiation. Related to B2B commerce, intelligent agents are involved in partnership formation, brokering and negotiation.

  3. Conversational Agents in E-Learning

    Science.gov (United States)

    Kerry, Alice; Ellis, Richard; Bull, Susan

    This paper discusses the use of natural language or 'conversational' agents in e-learning environments. We describe and contrast the various applications of conversational agent technology represented in the e-learning literature, including tutors, learning companions, language practice and systems to encourage reflection. We offer two more detailed examples of conversational agents, one which provides learning support, and the other support for self-assessment. Issues and challenges for developers of conversational agent systems for e-learning are identified and discussed.

  4. Multi-agent and complex systems

    CERN Document Server

    Ren, Fenghui; Fujita, Katsuhide; Zhang, Minjie; Ito, Takayuki

    2017-01-01

    This book provides a description of advanced multi-agent and artificial intelligence technologies for the modeling and simulation of complex systems, as well as an overview of the latest scientific efforts in this field. A complex system features a large number of interacting components, whose aggregate activities are nonlinear and self-organized. A multi-agent system is a group or society of agents which interact with others cooperatively and/or competitively in order to reach their individual or common goals. Multi-agent systems are suitable for modeling and simulation of complex systems, which is difficult to accomplish using traditional computational approaches.

  5. Multi-agent systems simulation and applications

    CERN Document Server

    Uhrmacher, Adelinde M

    2009-01-01

    Methodological Guidelines for Modeling and Developing MAS-Based SimulationsThe intersection of agents, modeling, simulation, and application domains has been the subject of active research for over two decades. Although agents and simulation have been used effectively in a variety of application domains, much of the supporting research remains scattered in the literature, too often leaving scientists to develop multi-agent system (MAS) models and simulations from scratch. Multi-Agent Systems: Simulation and Applications provides an overdue review of the wide ranging facets of MAS simulation, i

  6. Agent-Based Negotiation in Uncertain Environments

    Science.gov (United States)

    Debenham, John; Sierra, Carles

    An agent aims to secure his projected needs by attempting to build a set of (business) relationships with other agents. A relationship is built by exchanging private information, and is characterised by its intimacy — degree of closeness — and balance — degree of fairness. Each argumentative interaction between two agents then has two goals: to satisfy some immediate need, and to do so in a way that develops the relationship in a desired direction. An agent's desire to develop each relationship in a particular way then places constraints on the argumentative utterances. The form of negotiation described is argumentative interaction constrained by a desire to develop such relationships.

  7. Toddlers Selectively Help Fair Agents

    Directory of Open Access Journals (Sweden)

    Luca Surian

    2017-06-01

    Full Text Available Previous research showed that infants and toddlers are inclined to help prosocial agents and assign a positive valence to fair distributions. Also, they expect that positive and negative actions directed toward distributors will conform to reciprocity principles. This study investigates whether toddlers are selective in helping others, as a function of others’ previous distributive actions. Toddlers were presented with real-life events in which two actresses distributed resources either equally or unequally between two puppets. Then, they played together with a ball that accidentally fell to the ground and asked participants to help them to retrieve it. Participants preferred to help the actress who performed equal distributions. This finding suggests that by the second year children’s prosocial actions are modulated by their emerging sense of fairness.HighlightsToddlers (mean age = 25 months are selective in helping distributors.Toddlers prefer helping a fair rather than an unfair distributor.Toddlers’ selective helping provides evidence for an early sense of fairness.

  8. Viruses: agents of coral disease?

    Science.gov (United States)

    Davy, S K; Burchett, S G; Dale, A L; Davies, P; Davy, J E; Muncke, C; Hoegh-Guldberg, O; Wilson, W H

    2006-03-23

    The potential role of viruses in coral disease has only recently begun to receive attention. Here we describe our attempts to determine whether viruses are present in thermally stressed corals Pavona danai, Acropora formosa and Stylophora pistillata and zoanthids Zoanthus sp., and their zooxanthellae. Heat-shocked P. danai, A. formosa and Zoanthus sp. all produced numerous virus-like particles (VLPs) that were evident in the animal tissue, zooxanthellae and the surrounding seawater; VLPs were also seen around heat-shocked freshly isolated zooxanthellae (FIZ) from P. danai and S. pistillata. The most commonly seen VLPs were tail-less, hexagonal and about 40 to 50 nm in diameter, though a diverse range of other VLP morphotypes (e.g. rounded, rod-shaped, droplet-shaped, filamentous) were also present around corals. When VLPs around heat-shocked FIZ from S. pistillata were added to non-stressed FIZ from this coral, they resulted in cell lysis, suggesting that an infectious agent was present; however, analysis with transmission electron microscopy provided no clear evidence of viral infection. The release of diverse VLPs was again apparent when flow cytometry was used to enumerate release by heat-stressed A. formosa nubbins. Our data support the infection of reef corals by viruses, though we cannot yet determine the precise origin (i.e. coral, zooxanthellae and/or surface microbes) of the VLPs seen. Furthermore, genome sequence data are required to establish the presence of viruses unequivocally.

  9. Novel Methylselenoesters as Antiproliferative Agents.

    Science.gov (United States)

    Díaz-Argelich, Nuria; Encío, Ignacio; Plano, Daniel; Fernandes, Aristi P; Palop, Juan Antonio; Sanmartín, Carmen

    2017-08-02

    Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH₃SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH₃SeH. The fifteen compounds follow Lipinski's Rule of Five and with exception of compounds 1 and 14 , present better drug-likeness values than the positive control methylseleninic acid. The compounds were evaluated to determine their radical scavenging activity. Compound 11 reduced both DPPH and ABTS radicals. The cytotoxicity of the compounds was evaluated in a panel of five cancer cell lines (prostate, colon and lung carcinoma, mammary adenocarcinoma and chronic myelogenous leukemia) and two non-malignant (lung and mammary epithelial) cell lines. Ten compounds had GI 50 values below 10 μM at 72 h in four cancer cell lines. Compounds 5 and 15 were chosen for further characterization of their mechanism of action in the mammary adenocarcinoma cell line due to their similarity with methylseleninic acid. Both compounds induced G₂/M arrest whereas cell death was partially executed by caspases. The reduction and metabolism were also investigated, and both compounds were shown to be substrates for redox active enzyme thioredoxin reductase.

  10. Novel Methylselenoesters as Antiproliferative Agents

    Directory of Open Access Journals (Sweden)

    Nuria Díaz-Argelich

    2017-08-01

    Full Text Available Selenium (Se compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH3SeH. The fifteen compounds follow Lipinski’s Rule of Five and with exception of compounds 1 and 14, present better drug-likeness values than the positive control methylseleninic acid. The compounds were evaluated to determine their radical scavenging activity. Compound 11 reduced both DPPH and ABTS radicals. The cytotoxicity of the compounds was evaluated in a panel of five cancer cell lines (prostate, colon and lung carcinoma, mammary adenocarcinoma and chronic myelogenous leukemia and two non-malignant (lung and mammary epithelial cell lines. Ten compounds had GI50 values below 10 μM at 72 h in four cancer cell lines. Compounds 5 and 15 were chosen for further characterization of their mechanism of action in the mammary adenocarcinoma cell line due to their similarity with methylseleninic acid. Both compounds induced G2/M arrest whereas cell death was partially executed by caspases. The reduction and metabolism were also investigated, and both compounds were shown to be substrates for redox active enzyme thioredoxin reductase.

  11. Direct anti-HCV agents

    Directory of Open Access Journals (Sweden)

    Xingquan Zhang

    2016-01-01

    Full Text Available Unlike human immunodeficiency virus (HIV and hepatitis B virus (HBV, hepatitis C virus (HCV infection is a curable disease. Current direct antiviral agent (DAA targets are focused on HCV NS3/4A protein (protease, NS5B protein (polymerase and NS5A protein. The first generation of DAAs includes boceprevir and telaprevir, which are protease inhibitors and were approved for clinical use in 2011. The cure rate for genotype 1 patients increased from 45% to 70% when boceprevir or telaprevir was added to standard PEG-IFN/ribavirin. More effective and less toxic second generation DAAs supplanted these drugs by 2013. The second generation of DAAs includes sofosbuvir (Sovaldi, simeprevir (Olysio, and fixed combination medicines Harvoni and Viekira Pak. These drugs increase cure rates to over 90% without the need for interferon and effectively treat all HCV genotypes. With these drugs the “cure HCV” goal has become a reality. Concerns remain about drug resistance mutations and the high cost of these drugs. The investigation of new HCV drugs is progressing rapidly; fixed dose combination medicines in phase III clinical trials include Viekirax, asunaprevir+daclatasvir+beclabuvir, grazoprevir+elbasvir and others.

  12. Departments as Agents of Change

    Science.gov (United States)

    Lagowski, J. J.

    1996-07-01

    Higher education is changing because it has no choice. And, for the most part, outside influences are dictating the processes of change. The more fortunate institutions have had a flat budget during this period, but most have been forced to deal with a declining revenue stream as well. Legislators seem bent on micromanaging state-supported institutions, even as they cut their support. Regulators demand greater institutional accountability. Students and their parents expect more service at lower prices and increased flexibility. Technological advances have dramatically affected the availability and accessibility of extant knowledge. It is no longer a question of whether institutions will change, but rather, who will control the change. Most institutions possess long-standing academic traditions, but these are placed at risk in an increasingly competitive market that holds little sympathy for such traditions and may even see them as obstacles or barriers. As a result, the change agents will undoubtedly have a profound effect on the very nature of academic institutions. From the academic point of view, it would seem prudent to attempt to manage the changes that will inevitably occur. A number of concerned observers, notably the Pew Higher Education Roundtable and the American Association for Higher Education, argue persuasively that the academic department is the logical focus for responding to the current winds of change. Using a marketing metaphor, the academic department has been likened to a "producers' cooperative" of services that consumers seek. Thus, the department should be held accountable for the quality of teaching delivered by its members, for the coherence of its major, for its contributions to the general education curriculum, and for supervising and rewarding its individual faculty members. If departments are to be held accountable, it is surely in their best interest to act in such a way that they are accountable. Expecting academic departments to be

  13. Novel infectious agents causing uveitis.

    Science.gov (United States)

    Khairallah, Moncef; Chee, Soon Phaik; Rathinam, Sivakumar R; Attia, Sonia; Nadella, Venu

    2010-10-01

    In any patient with uveitis, an infectious cause should be ruled out first. The differential diagnosis includes multiple well-known diseases including herpes, syphilis, toxoplasmosis, tuberculosis, bartonellosis, Lyme disease, and others. However, clinician should be aware of emerging infectious agents as potential causes of systemic illness and also intraocular inflammation. Air travel, immigration, and globalization of business have overturned traditional pattern of geographic distribution of infectious diseases, and therefore one should work locally but think globally. This review recapitulates the systemic and ocular manifestations of several emergent infectious diseases relevant to the ophthalmologist including Rickettsioses, West Nile virus infection, Rift valley fever, Dengue fever, and Chikungunya. Retinitis, chorioretinitis, retinal vasculitis, and optic nerve involvement have been associated with these emergent infectious diseases. The diagnosis of any of these infections is usually based on pattern of uveitis, systemic symptoms and signs, and specific epidemiological data and confirmed by detection of specific antibody in serum. A systematic ocular examination, showing fairly typical fundus findings, may help establish an early clinical diagnosis, which allows prompt, appropriate management.

  14. Application Framework with Abstractions for Protocol and Agent Role

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun

    2016-01-01

    In multi-agent systems, agents interact by sending and receiving messages and the actual sequences of message form interaction structures between agents. Protocols and agents organized internally by agent roles support these interaction structures. Description and use of protocols based on agent ...... roles are supported by a simple and expressive application framework....

  15. Ultrasound contrast agents: An overview

    International Nuclear Information System (INIS)

    Cosgrove, David

    2006-01-01

    With the introduction of microbubble contrast agents, diagnostic ultrasound has entered a new era that allows the dynamic detection of tissue flow of both the macro and microvasculature. Underpinning this development is the fact that gases are compressible, and thus the microbubbles expand and contract in the alternating pressure waves of the ultrasound beam, while tissue is almost incompressible. Special software using multiple pulse sequences separates these signals from those of tissue and displays them as an overlay or on a split screen. This can be done at low acoustic pressures (MI < 0.3) so that the microbubbles are not destroyed and scanning can continue in real time. The clinical roles of contrast enhanced ultrasound scanning are expanding rapidly. They are established in echocardiography to improve endocardial border detection and are being developed for myocardial perfusion. In radiology, the most important application is the liver, especially for focal disease. The approach parallels that of dynamic CT or MRI but ultrasound has the advantages of high spatial and temporal resolution. Thus, small lesions that can be indeterminate on CT can often be studied with ultrasound, and situations where the flow is very rapid (e.g., focal nodular hyperplasia where the first few seconds of arterial perfusion may be critical to making the diagnosis) are readily studied. Microbubbles linger in the extensive sinusoidal space of normal liver for several minutes whereas they wash out rapidly from metastases, which have a low vascular volume and thus appear as filling defects. The method has been shown to be as sensitive as three-phase CT. Microbubbles have clinical uses in many other applications where knowledge of the microcirculation is important (the macrocirculation can usually be assessed adequately using conventional Doppler though there are a few important situations where the signal boost given by microbubbles is useful, e.g., transcranial Doppler for evaluating

  16. Ultrasound contrast agents: an overview.

    Science.gov (United States)

    Cosgrove, David

    2006-12-01

    With the introduction of microbubble contrast agents, diagnostic ultrasound has entered a new era that allows the dynamic detection of tissue flow of both the macro and microvasculature. Underpinning this development is the fact that gases are compressible, and thus the microbubbles expand and contract in the alternating pressure waves of the ultrasound beam, while tissue is almost incompressible. Special software using multiple pulse sequences separates these signals from those of tissue and displays them as an overlay or on a split screen. This can be done at low acoustic pressures (MI<0.3) so that the microbubbles are not destroyed and scanning can continue in real time. The clinical roles of contrast enhanced ultrasound scanning are expanding rapidly. They are established in echocardiography to improve endocardial border detection and are being developed for myocardial perfusion. In radiology, the most important application is the liver, especially for focal disease. The approach parallels that of dynamic CT or MRI but ultrasound has the advantages of high spatial and temporal resolution. Thus, small lesions that can be indeterminate on CT can often be studied with ultrasound, and situations where the flow is very rapid (e.g., focal nodular hyperplasia where the first few seconds of arterial perfusion may be critical to making the diagnosis) are readily studied. Microbubbles linger in the extensive sinusoidal space of normal liver for several minutes whereas they wash out rapidly from metastases, which have a low vascular volume and thus appear as filling defects. The method has been shown to be as sensitive as three-phase CT. Microbubbles have clinical uses in many other applications where knowledge of the microcirculation is important (the macrocirculation can usually be assessed adequately using conventional Doppler though there are a few important situations where the signal boost given by microbubbles is useful, e.g., transcranial Doppler for evaluating

  17. Evolution of hemostatic agents in surgical practice

    Directory of Open Access Journals (Sweden)

    Chandru P Sundaram

    2010-01-01

    Conclusions : A review of the evolution of topical hemostatic agents highlights opportunities for potential novel research. Fibrin sealants may have the most opportunity for advancement, and understanding the history of these products is useful. With the drive in urology for minimally invasive surgical techniques, adaptation of topical hemostatic agents to this surgical approach would be valuable and offers an opportunity for novel contributions.

  18. Computational Intelligence Agent-Oriented Modelling

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman

    2006-01-01

    Roč. 5, č. 2 (2006), s. 430-433 ISSN 1109-2777 R&D Projects: GA MŠk 1M0567 Institutional research plan: CEZ:AV0Z10300504 Keywords : multi-agent systems * adaptive agents * computational intelligence Subject RIV: IN - Informatics, Computer Science

  19. Agent Based Reasoning in Multilevel Flow Modeling

    DEFF Research Database (Denmark)

    Lind, Morten; Zhang, Xinxin

    2012-01-01

    to launch the MFM Workbench into an agent based environment, which can complement disadvantages of the original software. The agent-based MFM Workbench is centered on a concept called “Blackboard System” and use an event based mechanism to arrange the reasoning tasks. This design will support the new...

  20. Anonymity and Software Agents: An Interdiscplinary Challenge

    NARCIS (Netherlands)

    Brazier, F.M.; Oskamp, A.; Prins, J.M.; Schellekens, M.H.M.; Wijngaards, N.J.E.

    2004-01-01

    Software agents that play a role in E-commerce and E-government applications involving the Internet often contain information about the identity of their human user such as credit cards and bank accounts. This paper discusses whether this is necessary: whether human users and software agents are

  1. Anonymity and Software Agents: An Interdisciplinary Challenge

    NARCIS (Netherlands)

    Oskamp, A.; Brazier, F.M.; Prins, J.E.J.; Schellekens, M.H.M.; Wijngaards, N.J.E.

    2004-01-01

    Software agents that play a role in E-commerce and E-government applications involving the Internet often contain information about the identity of their human user such as credit cards and bank accounts. This paper discusses whether this is necessary: whether human users and software agents are

  2. Dynamics of three-agent games

    International Nuclear Information System (INIS)

    Mungan, Muhittin; Rador, Tonguc

    2008-01-01

    We study the dynamics and resulting score distribution of three-agent games where after each competition a single agent wins and scores a point. A single competition is described by a triplet of numbers p, t and q denoting the probabilities that the team with the highest, middle or lowest accumulated score wins. The three-agent game can be regarded as a social model where a player can be favored or disfavored for advancement, based on his/her accumulated score. We study the full family of solutions in the regime, where the number of agents and competitions is large, which can be regarded as a hydrodynamic limit. Depending on the parameter values (p, q, t), we find six qualitatively different asymptotic score distributions and we provide a qualitative explanation of these results. We also compare our analytical results against numerical simulations of the microscopic model and find these to be in excellent agreement. It is possible to decide the outcome of a three-agent game through a mini-tournament of two-agent competitions among the participating players and it turns out that the resulting possible score distributions are a subset of those obtained for the general three-agent games. We discuss how one can add a steady and democratic decline rate to the model and present a simple geometric construction that allows one to obtain the score evolution equations for n-agent games

  3. On conversational agents with mental states

    NARCIS (Netherlands)

    Bosse, T.; Provoost, S.

    2015-01-01

    Embodied conversational agents (ECAs) have been put forward as a promising means for the training of social skills. The traditional approach to drive the behaviour of ECAs during human-agent dialogues is to use conversation trees. Although this approach is easy to use and very transparent, an

  4. Explanation in human-agent teamwork

    NARCIS (Netherlands)

    Harbers, M.; Bradshaw, J.M.; Johnson, M.; Feltovich, P.; Bosch, K. van den; Meyer, J.J.C.

    2012-01-01

    There are several applications in which humans and agents jointly perform a task. If the task involves interdependence among the team members, coordination is required to achieve good team performance. This paper discusses the role of explanation in coordination in human-agent teams. Explanations

  5. assessment of extension agents' communication methods

    African Journals Online (AJOL)

    USER

    ABSTRACT. The need to improve aquaculture production through enhanced technology transfer necessitated this study to assess extension agents' use of communication methods and its impact on linkage. A structured questionnaire was administered to 44 extension agents who were randomly selected from Lagos State ...

  6. Mansion, A Distributed Multi-Agent System

    NARCIS (Netherlands)

    van t Noordende, G.; Brazier, F.M.; Tanenbaum, A.S.

    2001-01-01

    In this position summary we present work in progress on a worldwide, scalable multi-agent system, based on a paradigm of hyperlinked rooms. The framework offers facilities for managing distribution, security and mobility aspects for both active elements (agents) and passive elements (objects) in the

  7. Some Pitfalls for Developing Enculturated Conversational Agents

    DEFF Research Database (Denmark)

    Rehm, Matthias; André, Elisabeth; Nakano, Yukiko

    2009-01-01

    A review of current agent-based systems exemplifies that a Western perspective is predominant in the field. But as conversational agents focus on rich multimodal interactive behaviors that underlie face-to-face encounters, it is indispensable to incorporate cultural heuristics of such behaviors...

  8. Security of Mobile Agents on the Internet.

    Science.gov (United States)

    Corradi, Antonio; Montanari, Rebecca; Stefanelli, Cesare

    2001-01-01

    Discussion of the Internet focuses on new programming paradigms based on mobile agents. Considers the security issues associated with mobile agents and proposes a security architecture composed of a wide set of services and components capable of adapting to a variety of applications, particularly electronic commerce. (Author/LRW)

  9. Inhabited interfaces : Attentive conversational agents that help

    NARCIS (Netherlands)

    Nijholt, Antinus; Heylen, Dirk K.J.; Vertegaal, R.P.H.; Sharkey, P.; Cesarani, A.; Pugnetti, L.; Rizzo, A.

    2000-01-01

    We discuss the role of attentive agents in virtual reality interfaces. This discussion is guided by experiences and experiments with a virtual reality environment we designed and implemented. In this environment we have introduced agents, sometimes embodied, with which the users can communicate

  10. Biomonitoring of exposure to chemical warfare agents

    NARCIS (Netherlands)

    Noort, D.; Schans, M.J. van der; Benschop, H.P.

    2006-01-01

    An overview is presented of the major methods that are presently available for biomonitoring of exposure to chemical warfare agents, i.e., nerve agents and sulfur mustard. These methods can be applied for a variety of purposes such as diagnosis and dosimetry of exposure of casualties, verification

  11. Deliberate Evolution in Multi-Agent Systems

    NARCIS (Netherlands)

    Brazier, F.M.; Jonker, C.M.; Treur, J.; Wijngaards, N.J.E.; Gabbay, D.

    2001-01-01

    Evolution in societies of agents is a challenging phenomenon, both from a fundamental perspective and from an applied perspective. In the literature often genetic programming approaches are used and relatively simple agents are considered, which have no deliberate influence on the direction of the

  12. AGENT: Awareness Game Environment for Natural Training

    NARCIS (Netherlands)

    Linssen, Johannes Maria; de Groot, Thomas

    We propose AGENT, the Awareness Game Environment for Natural Training, as a virtual environment in which serious games can be enacted. AGENT combines research on interactive storytelling, game design, turn-taking and social signal processing with a multi-modal UI in a modular fashion. Current work

  13. Assurance in Agent-Based Systems

    Energy Technology Data Exchange (ETDEWEB)

    Gilliom, Laura R.; Goldsmith, Steven Y.

    1999-05-10

    Our vision of the future of information systems is one that includes engineered collectives of software agents which are situated in an environment over years and which increasingly improve the performance of the overall system of which they are a part. At a minimum, the movement of agent and multi-agent technology into National Security applications, including their use in information assurance, is apparent today. The use of deliberative, autonomous agents in high-consequence/high-security applications will require a commensurate level of protection and confidence in the predictability of system-level behavior. At Sandia National Laboratories, we have defined and are addressing a research agenda that integrates the surety (safety, security, and reliability) into agent-based systems at a deep level. Surety is addressed at multiple levels: The integrity of individual agents must be protected by addressing potential failure modes and vulnerabilities to malevolent threats. Providing for the surety of the collective requires attention to communications surety issues and mechanisms for identifying and working with trusted collaborators. At the highest level, using agent-based collectives within a large-scale distributed system requires the development of principled design methods to deliver the desired emergent performance or surety characteristics. This position paper will outline the research directions underway at Sandia, will discuss relevant work being performed elsewhere, and will report progress to date toward assurance in agent-based systems.

  14. Assurance in Agent-Based Systems

    International Nuclear Information System (INIS)

    Gilliom, Laura R.; Goldsmith, Steven Y.

    1999-01-01

    Our vision of the future of information systems is one that includes engineered collectives of software agents which are situated in an environment over years and which increasingly improve the performance of the overall system of which they are a part. At a minimum, the movement of agent and multi-agent technology into National Security applications, including their use in information assurance, is apparent today. The use of deliberative, autonomous agents in high-consequence/high-security applications will require a commensurate level of protection and confidence in the predictability of system-level behavior. At Sandia National Laboratories, we have defined and are addressing a research agenda that integrates the surety (safety, security, and reliability) into agent-based systems at a deep level. Surety is addressed at multiple levels: The integrity of individual agents must be protected by addressing potential failure modes and vulnerabilities to malevolent threats. Providing for the surety of the collective requires attention to communications surety issues and mechanisms for identifying and working with trusted collaborators. At the highest level, using agent-based collectives within a large-scale distributed system requires the development of principled design methods to deliver the desired emergent performance or surety characteristics. This position paper will outline the research directions underway at Sandia, will discuss relevant work being performed elsewhere, and will report progress to date toward assurance in agent-based systems

  15. Giving advice to agents with hidden goals

    CSIR Research Space (South Africa)

    Rosman, Benjamin S

    2014-05-01

    Full Text Available on an approximation of the trade-off in utility between potential benefits to the exploring agent and the costs incurred in giving this advice. This model is evaluated on a maze world domain by providing advice to different types of agents, and we show that this leads...

  16. Sanguinarine: A Novel Agent Against Prostate Cancer

    National Research Council Canada - National Science Library

    Ahmad, Nihal

    2005-01-01

    .... Therefore, the search for novel agents and approaches for the treatment of CaP continues. Natural plant-based products have shown promise as anticancer agents. Sanguinarine (13-methyl[ 1,3]benzodioxolo[5,6-c]- 1,3-dioxolo[4,5-i]phenanthridinium...

  17. Marine Natural Products as Prototype Agrochemical Agents

    Science.gov (United States)

    Peng, Jiangnan; Shen, Xiaoyu; El Sayed, Khalid A.; Dunbar, D. C Harles; Perry, Tony L.; Wilkins, Scott P.; Hamann, Mark T.; Bobzin, Steve; Huesing, Joseph; Camp, Robin; Prinsen, Mike; Krupa, Dan; Wideman, Margaret A.

    2016-01-01

    In the interest of identifying new leads that could serve as prototype agrochemical agents, 18 structurally diverse marine-derived compounds were examined for insecticidal, herbicidal, and fungicidal activities. Several new classes of compounds have been shown to be insecticidal, herbicidal, and fungicidal, which suggests that marine natural products represent an intriguing source for the discovery of new agrochemical agents. PMID:12670165

  18. 21 CFR 181.28 - Release agents.

    Science.gov (United States)

    2010-04-01

    ... Release agents. Substances classified as release agents, when migrating from food-packaging material shall...). Linoleamide (linoleic acid amide). Oleamide (oleic acid amide). Palmitamide (palmitic acid amide). Stearamide (stearic acid amide). [42 FR 14638, Mar. 15, 1977; 42 FR 56728, Oct. 28, 1977] ...

  19. BOA: A cognitive tactical picture compilation agent

    NARCIS (Netherlands)

    Heuvelink, A.; Both, F.

    2007-01-01

    Simulation-based training in complex decision-making can be made more effective by using intelligent software agents to play key roles, such as teammates, opponents and instructors. This paper presents a cognitive software agent that is capable of compiling a tactical picture in the domain of Naval

  20. Cognitive agent programming : A semantic approach

    NARCIS (Netherlands)

    Riemsdijk, M.B. van

    2006-01-01

    In this thesis we are concerned with the design and investigation of dedicated programming languages for programming agents. We focus in particular on programming languages for rational agents, i.e., flexibly behaving computing entities that are able to make "good" decisions about what to do. An

  1. Mechanisms of bacterial resistance to antimicrobial agents.

    NARCIS (Netherlands)

    van Duijkeren, Engeline; Schink, Anne-Kathrin; Roberts, Marilyn C; Wang, Yang; Schwarz, Stefan

    During the past decades resistance to virtually all antimicrobial agents has been observed in bacteria of animal origin. This chapter describes in detail the mechanisms so far encountered for the various classes of antimicrobial agents. The main mechanisms include enzymatic inactivation by either

  2. Moral conflicts between groups of agents

    NARCIS (Netherlands)

    Kooi, Barteld; Tamminga, A.

    Two groups of agents, G1 and G2, face a *moral conflict* if G1 has a moral obligation and G2 has a moral obligation, such that these obligations cannot both be fulfilled. We study moral conflicts using a multi-agent deontic logic devised to represent reasoning about sentences like 'In the interest

  3. 7 CFR 983.86 - Agents.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Agents. 983.86 Section 983.86 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... NEW MEXICO Miscellaneous Provisions § 983.86 Agents. The Secretary may, by a designation in writing...

  4. Econophysics of agent-based models

    CERN Document Server

    Aoyama, Hideaki; Chakrabarti, Bikas; Chakraborti, Anirban; Ghosh, Asim

    2014-01-01

    The primary goal of this book is to present the research findings and conclusions of physicists, economists, mathematicians and financial engineers working in the field of "Econophysics" who have undertaken agent-based modelling, comparison with empirical studies and related investigations. Most standard economic models assume the existence of the representative agent, who is “perfectly rational” and applies the utility maximization principle when taking action. One reason for this is the desire to keep models mathematically tractable: no tools are available to economists for solving non-linear models of heterogeneous adaptive agents without explicit optimization. In contrast, multi-agent models, which originated from statistical physics considerations, allow us to go beyond the prototype theories of traditional economics involving the representative agent. This book is based on the Econophys-Kolkata VII Workshop, at which many such modelling efforts were presented. In the book, leading researchers in the...

  5. Agent-based models of cellular systems.

    Science.gov (United States)

    Cannata, Nicola; Corradini, Flavio; Merelli, Emanuela; Tesei, Luca

    2013-01-01

    Software agents are particularly suitable for engineering models and simulations of cellular systems. In a very natural and intuitive manner, individual software components are therein delegated to reproduce "in silico" the behavior of individual components of alive systems at a given level of resolution. Individuals' actions and interactions among individuals allow complex collective behavior to emerge. In this chapter we first introduce the readers to software agents and multi-agent systems, reviewing the evolution of agent-based modeling of biomolecular systems in the last decade. We then describe the main tools, platforms, and methodologies available for programming societies of agents, possibly profiting also of toolkits that do not require advanced programming skills.

  6. Fault Reconnaissance Agent for Sensor Networks

    Directory of Open Access Journals (Sweden)

    Elhadi M. Shakshuki

    2010-01-01

    Full Text Available One of the key prerequisite for a scalable, effective and efficient sensor network is the utilization of low-cost, low-overhead and high-resilient fault-inference techniques. To this end, we propose an intelligent agent system with a problem solving capability to address the issue of fault inference in sensor network environments. The intelligent agent system is designed and implemented at base-station side. The core of the agent system – problem solver – implements a fault-detection inference engine which harnesses Expectation Maximization (EM algorithm to estimate fault probabilities of sensor nodes. To validate the correctness and effectiveness of the intelligent agent system, a set of experiments in a wireless sensor testbed are conducted. The experimental results show that our intelligent agent system is able to precisely estimate the fault probability of sensor nodes.

  7. Advances on Practical Applications of Agents and Multi-Agent Systems 10th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Müller, Jörg; Rodríguez, Juan; Pérez, Javier

    2012-01-01

    Research on Agents and Multi-Agent Systems has matured during the last decade and many effective applications of this technology are now deployed. PAAMS provides an international forum to present and discuss the latest scientific developments and their effective applications, to assess the impact of the approach, and to facilitate technology transfer. PAAMS started as a local initiative, but has since grown to become THE international yearly platform to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development and deployment of Agents and Multi-Agent Systems. PAAMS intends to bring together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on the application of multi-agent systems, to discuss and debate the major ...

  8. Highlights on Practical Applications of Agents and Multi-Agent Systems 10th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Sánchez, Miguel; Mathieu, Philippe; Rodríguez, Juan; Adam, Emmanuel; Ortega, Alfonso; Moreno, María; Navarro, Elena; Hirsch, Benjamin; Lopes-Cardoso, Henrique; Julián, Vicente

    2012-01-01

    Research on Agents and Multi-Agent Systems has matured during the last decade and many effective applications of this technology are now deployed. PAAMS provides an international forum to present and discuss the latest scientific developments and their effective applications, to assess the impact of the approach, and to facilitate technology transfer. PAAMS started as a local initiative, but has since grown to become THE international yearly platform to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development and deployment of Agents and Multi-Agent Systems. PAAMS intends to bring together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on the application of multi-agent systems, to discuss and debate the major ...

  9. In vitro testing of plaque control agents.

    Science.gov (United States)

    Coburn, R A

    1979-12-01

    The development of a number of in vitro techniques for the evaluation of antiplaque effects of test agents has followed the characterization and culturing of plaque-forming microorganisms. Studies of the mechanism of action of chlorhexidine and clinical observations have assisted in defining critical aspects of these in vitro techniques. Such assays may play an increasingly important role in screening potential new agents as well as in the optimization of properties by chemical modification of new lead agents. In addition, data generated in the in vitro assay may assist the design of in vivo evaluations of new agents. Proper selection of in vitro techniques for these various functions in the pre-clinical development process may reduce the time and cost involved in the development of new antiplaque agents.

  10. Biological agents in polyarticular juvenile idiopathic arthritis

    DEFF Research Database (Denmark)

    Amarilyo, Gil; Tarp, Simon; Foeldvari, Ivan

    2016-01-01

    (nearly all exceptions were in agreement with the original study data). Serious AEs occurred very infrequently (0-8%) and an analysis was not possible. There were no differences for AEs when compared among biological agents or to placebo. CONCLUSION: There were no statistical differences among biological......BACKGROUND AND OBJECTIVE: Although various biological agents are in use for polyarticular juvenile idiopathic arthritis (pJIA), head-to-head trials comparing the efficacy and safety among them are lacking. We aimed to compare the efficacy and safety of biological agents in pJIA using all currently...... available randomized withdrawal trials (wRCTs). METHODS: A systematic search of MEDLINE, EMBASE, CENTRAL, and clinicaltrials.gov was performed. Eligible wRCTs: patients with pJIA where a biological agent was compared with another biological agent or placebo. Efficacy was evaluated using disease flare...

  11. CEST and PARACEST MR contrast agents

    Energy Technology Data Exchange (ETDEWEB)

    Hancu, Ileana; Dixon, W. Thomas (GE Global Research Center, Niskayuna, NY (United States)); Woods, Mark; Sherry, A. Dean (Univ. of Texas at Dallas, Dallas, TX (United States)); Vinogradov, Elena; Lenkinski, Robert E. (Beth Israel Deaconess Medical Center, Boston, MA (United States)), e-mail: rlenkins@bidmc.harvard.edu

    2010-10-15

    In this review we describe the status of development for a new class of magnetic resonance (MR) contrast agents, based on chemical exchange saturation transfer (CEST). The mathematics and physics relevant to the description of the CEST effect in MR are presented in an appendix published in the online version only. We discuss the issues arising when translating in vitro results obtained with CEST agents to using these MR agents in in vivo model studies and in humans. Examples are given on how these agents are imaged in vivo. We summarize the status of development of these CEST agents, and speculate about the next steps that may be taken towards the demonstration of CEST MR imaging in clinical applications

  12. The agent-relative/agent-neutral distinction: my two sense(s) | Lerm ...

    African Journals Online (AJOL)

    -relative in the dependence sense but agent-neutral in the homogeneous sense, and – perhaps surprisingly – of Utilitarianism, according to which reasons are agent-neutral in the independence sense but agent-relative in the heterogeneous ...

  13. Human-agent experience sharing : Creating social agents for elderly people with dementia

    NARCIS (Netherlands)

    Peeters, M.M.M.; Neerincx, M.A.

    2016-01-01

    As intelligent technology steadily becomes a part of modern societies, people collaborate with agents more frequently, and so agents need to be socially intelligent, i.e. personalised and context-sensitive. This paper introduces a context-sensitive personalisation framework for social agents that

  14. 9th KES Conference on Agent and Multi-Agent Systems : Technologies and Applications

    CERN Document Server

    Howlett, Robert; Jain, Lakhmi

    2015-01-01

    Agents and multi-agent systems are related to a modern software paradigm which has long been recognized as a promising technology for constructing autonomous, complex and intelligent systems. The topics covered in this volume include agent-oriented software engineering, agent co-operation, co-ordination, negotiation, organization and communication, distributed problem solving, specification of agent communication languages, agent privacy, safety and security, formalization of ontologies and conversational agents. The volume highlights new trends and challenges in agent and multi-agent research and includes 38 papers classified in the following specific topics: learning paradigms, agent-based modeling and simulation, business model innovation and disruptive technologies, anthropic-oriented computing, serious games and business intelligence, design and implementation of intelligent agents and multi-agent systems, digital economy, and advances in networked virtual enterprises. Published p...

  15. For whom will the Bayesian agents vote?

    Science.gov (United States)

    Caticha, Nestor; Cesar, Jonatas; Vicente, Renato

    2015-04-01

    Within an agent-based model where moral classifications are socially learned, we ask if a population of agents behaves in a way that may be compared with conservative or liberal positions in the real political spectrum. We assume that agents first experience a formative period, in which they adjust their learning style acting as supervised Bayesian adaptive learners. The formative phase is followed by a period of social influence by reinforcement learning. By comparing data generated by the agents with data from a sample of 15000 Moral Foundation questionnaires we found the following. 1. The number of information exchanges in the formative phase correlates positively with statistics identifying liberals in the social influence phase. This is consistent with recent evidence that connects the dopamine receptor D4-7R gene, political orientation and early age social clique size. 2. The learning algorithms that result from the formative phase vary in the way they treat novelty and corroborative information with more conservative-like agents treating it more equally than liberal-like agents. This is consistent with the correlation between political affiliation and the Openness personality trait reported in the literature. 3. Under the increase of a model parameter interpreted as an external pressure, the statistics of liberal agents resemble more those of conservative agents, consistent with reports on the consequences of external threats on measures of conservatism. We also show that in the social influence phase liberal-like agents readapt much faster than conservative-like agents when subjected to changes on the relevant set of moral issues. This suggests a verifiable dynamical criterium for attaching liberal or conservative labels to groups.

  16. For whom will the Bayesian agents vote?

    Directory of Open Access Journals (Sweden)

    Nestor eCaticha

    2015-04-01

    Full Text Available Within an agent-based model where moral classifications are socially learned, we ask if a population of agents behaves in a way that may be compared with conservative or liberal positions in the real political spectrum. We assume that agents first experience a formative period, in which they adjust their learning style acting as supervised Bayesian adaptive learners. The formative phase is followed by a period of social influence by reinforcement learning. By comparing data generated by the agents with data from a sample of 15000 Moral Foundation questionnaires we found the following. 1. The number of information exchanges in the formative phase correlates positively with statistics identifying liberals in the social influence phase. This is consistent with recent evidence that connects the dopamine receptor D4-7R gene, political orientation and early age social clique size. 2. The learning algorithms that result from the formative phase vary in the way they treat novelty and corroborative information with more conservative-like agents treating it more equally than liberal-like agents. This is consistent with the correlation between political affiliation and the Openness personality trait reported in the literature. 3. Under the increase of a model parameter interpreted as an external pressure, the statistics of liberal agents resemble more those of conservative agents, consistent with reports on the consequences of external threats on measures of conservatism. We also show that in the social influence phase liberal-like agents readapt much faster than conservative-like agents when subjected to changes on the relevant set of moral issues. This suggests a verifiable dynamical criterium for attaching liberal or conservative labels to groups.

  17. Multi-Agent Systems for E-Commerce

    OpenAIRE

    Solodukha, T. V.; Sosnovskiy, O. A.; Zhelezko, B. A.

    2009-01-01

    The article focuses on multi-agent systems (MAS) and domains that can benefit from multi-agent technology. In the last few years, the agent based modeling (ABM) community has developed several practical agent based modeling toolkits that enable individuals to develop agent-based applications. The comparison of agent-based modeling toolkits is given. Multi-agent systems are designed to handle changing and dynamic business processes. Any organization with complex and distributed busine...

  18. Chemical Warfare Agent Decontaminant Solution Using Quaternary Ammonium Complexes

    Science.gov (United States)

    1997-12-11

    warfare agents, which include a variety of organophosphorus and organosulfur compounds, are known in the art. 15 However, these known methods use...chemical warfare agents, and works particularly well for neutralization of organosulfur agents such as mustard gas (HD), and organophosphorus agents such...detoxifying/neutralizing a variety of chemical warfare agents, including organosulfur agents such as mustard gas (HD), and organophosphorus agents such as

  19. Traitement de l'hétérogénéité sémantique dans les interactions humain-agent et agent-agent

    OpenAIRE

    Mazuel , Laurent

    2008-01-01

    The main purpose of this thesis is the management of semantic heterogeneity in human-agent and agent-agent interaction. We especially focus on the situation where a software agent, supplied with a knowledge representation model, has to understand requests coming from different interlocutors; either it is a human user or another software agent.Most work in this domain either focus on human-agent interaction or agent-agent interaction. On the contrary, we suggest that it is possible to use a co...

  20. Human butyrylcholinesterase efficacy against nerve agent exposure.

    Science.gov (United States)

    Reed, Beth A; Sabourin, Carol L; Lenz, David E

    2017-05-01

    Acetylcholinesterase is vital for normal operation of many processes in the body. Following exposure to organophosphorus (OP) nerve agents, death can ensue without immediate medical intervention. Current therapies mitigate the cholinergic crisis caused by nerve agents but do not fully prevent long-term health concerns, for example, brain damage following seizures. Human butyrylcholinesterase (HuBChE) is a stoichiometric bioscavenger being investigated as an antidote for OP nerve agent poisoning. HuBChE sequesters OP nerve agent in the bloodstream preventing the nerve agent from reaching critical target organ systems. HuBChE was effective when used as both a pre-treatment and as a post-exposure therapy. HuBChE has potential for use in both military settings and to protect civilian first responders in situations where nerve agent usage is suspected. We reviewed various animal models studies evaluating the efficacy of HuBChE against nerve agent exposure, pursuant to its submission for approval under the FDA Animal Rule. © 2017 Wiley Periodicals, Inc.

  1. Persistent agents in Axelrod's social dynamics model

    Science.gov (United States)

    Reia, Sandro M.; Neves, Ubiraci P. C.

    2016-01-01

    Axelrod's model of social dynamics has been studied under the effect of external media. Here we study the formation of cultural domains in the model by introducing persistent agents. These are agents whose cultural traits are not allowed to change but may be spread through local neighborhood. In the absence of persistent agents, the system is known to present a transition from a monocultural to a multicultural regime at some critical Q (number of traits). Our results reveal a dependence of critical Q on the occupation probability p of persistent agents and we obtain the phase diagram of the model in the (p,Q) -plane. The critical locus is explained by the competition of two opposite forces named here barrier and bonding effects. Such forces are verified to be caused by non-persistent agents which adhere (adherent agents) to the set of traits of persistent ones. The adherence (concentration of adherent agents) as a function of p is found to decay for constant Q. Furthermore, adherence as a function of Q is found to decay as a power law with constant p.

  2. Agent-Supported Mission Operations Teamwork

    Science.gov (United States)

    Malin, Jane T.

    2003-01-01

    This slide presentation reviews the development of software agents to support of mission operations teamwork. The goals of the work was to make automation by agents easy to use, supervise and direct, manage information and communication to decrease distraction, interruptions, workload and errors, reduce mission impact of off-nominal situations and increase morale and decrease turnover. The accomplishments or the project are: 1. Collaborative agents - mixed initiative and creation of instructions for mediating agent 2. Methods for prototyping, evaluating and evolving socio-technical systems 3. Technology infusion: teamwork tools in mISSIons 4. Demonstrations in simulation testbed An example of the use of agent is given, the use of an agent to monitor a N2 tank leak. An incomplete instruction to the agent is handled with mediating assistants, or Intelligent Briefing and Response Assistant (IBRA). The IBRA Engine also watches data stream for triggers and executes Act-Whenever actions. There is also a Briefing and Response Instruction (BRI) which is easy for a discipline specialist to create through a BRI editor.

  3. Continuum deformation of multi-agent systems

    CERN Document Server

    Rastgoftar, Hossein

    2016-01-01

    This monograph presents new algorithms for formation control of multi-agent systems (MAS) based on principles of continuum mechanics. Beginning with an overview of traditional methods, the author then introduces an innovative new approach whereby agents of an MAS are considered as particles in a continuum evolving in ℝn whose desired configuration is required to satisfy an admissible deformation function. The necessary theory and its validation on a mobile-agent-based swarm test bed are considered for two primary tasks: homogeneous transformation of the MAS and deployment of a random distribution of agents on a desired configuration. The framework for this model is based on homogeneous transformations for the evolution of an MAS under no inter-agent communication, local inter-agent communication, and intelligent perception by agents. Different communication protocols for MAS evolution, the robustness of tracking of a desired motion by an MAS evolving in ℝn, and the effect of communication delays in an MAS...

  4. Relay tracking control for second-order multi-agent systems with damaged agents.

    Science.gov (United States)

    Dong, Lijing; Li, Jing; Liu, Qin

    2017-11-01

    This paper investigates a situation where smart agents capable of sensory and mobility are deployed to monitor a designated area. A preset number of agents start tracking when a target intrudes this area. Some of the tracking agents are possible to be out of order over the tracking course. Thus, we propose a cooperative relay tracking strategy to ensure the successful tracking with existence of damaged agents. Relay means that, when a tracking agent quits tracking due to malfunction, one of the near deployed agents replaces it to continue the tracking task. This results in jump of tracking errors and dynamic switching of topology of the multi-agent system. Switched system technique is employed to solve this specific problem. Finally, the effectiveness of proposed tracking strategy and validity of the theoretical results are verified by conducting a numerical simulation. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  5. Agent and multi-Agent systems in distributed systems digital economy and e-commerce

    CERN Document Server

    Hartung, Ronald

    2013-01-01

    Information and communication technology, in particular artificial intelligence, can be used to support economy and commerce using digital means. This book is about agents and multi-agent distributed systems applied to digital economy and e-commerce to meet, improve, and overcome challenges in the digital economy and e-commerce sphere. Agent and multi-agent solutions are applied in implementing real-life, exciting developments associated with the need to eliminate problems of distributed systems.   The book presents solutions for both technology and applications, illustrating the possible uses of agents in the enterprise domain, covering design and analytic methods, needed to provide a solid foundation required for practical systems. More specifically, the book provides solutions for the digital economy, e-sourcing clusters in network economy, and knowledge exchange between agents applicable to online trading agents, and security solutions to both digital economy and e-commerce. Furthermore, it offers soluti...

  6. Multi-Agent Pathfinding with n Agents on Graphs with n Vertices

    DEFF Research Database (Denmark)

    Förster, Klaus-Tycho; Groner, Linus; Hoefler, Torsten

    2017-01-01

    We investigate the multi-agent pathfinding (MAPF) problem with $n$ agents on graphs with $n$ vertices: Each agent has a unique start and goal vertex, with the objective of moving all agents in parallel movements to their goal s.t.~each vertex and each edge may only be used by one agent at a time....... We give a combinatorial classification of all graphs where this problem is solvable in general, including cases where the solvability depends on the initial agent placement. Furthermore, we present an algorithm solving the MAPF problem in our setting, requiring O(n²) rounds, or O(n³) moves...... of individual agents. Complementing these results, we show that there are graphs where Omega(n²) rounds and Omega(n³) moves are required for any algorithm....

  7. Topical antimicrobial agents in ophthalmology. A review

    Directory of Open Access Journals (Sweden)

    E. V. Dovgan’

    2014-01-01

    Full Text Available The data on different antimicrobial agents (fluoroquinolones, minoglycosides, macrolides, fusidic acid, chloramphenicol and their activity against various microorganisms are reviewed. The findings from different researchers are analyzed. Considerable attention is devoted to the problem of antimicrobial resistance in ophthalmology. Pharmacokinetics of topical antimicrobial agents applied in ophthalmology, their safety and tolerability are described. The indications for topical antimicrobial agents use in ophthalmology approved in Russian Federation are presented. With regard for pharmacokinetics and pharmacodynamics, safety profile and good tolerability, it is concluded that fluoroquinolones are medication of choice for empirical antimicrobial treatment in ophthalmology.

  8. Process for preparation of MR contrast agents

    DEFF Research Database (Denmark)

    2002-01-01

    The present invention provides a process for the preparation of an MR contrast agent, said process comprising: i) obtaining a solution in a solvent of a hydrogenatable, unsaturated substrate compound and a catalyst for the hydrogenation of said substrate compound; ii) introducing said solution...... in droplet form into a chamber containing hydrogen gas (H2) enriched in para-hydrogen (p-1H2) and/or ortho-deuterium (o-2H2) whereby to hydrogenate said substrate to form a hydrogenated imaging agent; iii) optionally subjecting said hydrogenated imaging agent to a magnetic field having a field strength below...

  9. Mechanisms of resistance to alkylating agents

    OpenAIRE

    Damia, G.; D‘Incalci, M.

    1998-01-01

    Alkylating agents are the most widely used anticancer drugs whose main target is the DNA, although how exactly the DNA lesions cause cell death is still not clear. The emergence of resistance to this class of drugs as well as to other antitumor agents is one of the major causes of failure of cancer treatment. This paper reviews some of the best characterized mechanisms of resistance to alkylating agents. Pre- and post-target mechanisms are recognized, the former able to limit the formation of...

  10. AORTA: Adding Organizational Reasoning to Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Dignum, Virginia

    2014-01-01

    the expected behavior of the agents. Agents need to be able to reason about the regulations, so that they can act within the expected boundaries and work towards the objectives of the organization. This extended abstract introduces AORTA, a component that can be integrated into agents’ reasoning mechanism......, allowing them to reason about (and act upon) regulations specified by an organizational model using simple reasoning rules. The added value is that the organizational model is independent of that of the agents, and that the approach is not tied to a specific organizational model....

  11. Francisella tularensis - potential biological agent

    International Nuclear Information System (INIS)

    Taleski, V.

    2009-01-01

    Francisella tularensis is a small, nonmotile, aerobic, gram-negative coccobacillus capable of surviving for weeks at low temperatures in water, moist soil, hay, straw, or decaying animal carcasses. F. tularensis is the causative of the zoonotic disease tularemia. This bacterium was first identified in ground squirrels in Tulare County, California (1912). The human disease was recognized and described by Edward Francis (1922) as tularemia, and the agent was renamed Francisella tularensis in his honor. F. tularensis is one of the most infectious bacterial pathogens known, as few as 10-50 organisms can cause disease. Humans can become incidentally infected through diverse environmental exposures: bites by infected arthropods; handling infectious animal tissues or fluids; direct contact with or ingestion of contaminated food, water, or soil and inhalation of infective aerosols. Humans can develop severe and sometimes fatal illness, but do not transmit the disease to others. F. tularensis have few subspecies: 1) F. tularensis subsp. tularensis (type A), highly virulent, found only in North America. The bacterium is transmitted among animals and from animals to humans by ticks, occasionally deerfly, or by aerosols; 2) F. tularensis subsp. holarctica (type B), moderately virulent, occurs in Euroasia and North America, mainly associated with streams, lakes, ponds, rivers and semi-aquatic animals such as muskrats and beavers (water-borne disease). Type B tularemia has been observed during war times (during Second World War 100 000 cases occurred each year, in Kosovo in 2000 and 2003 over 300 cases each year); 3) F. tularensis subsp. mediasiatica, rarely reported, isolated only in Kazahstan and Turkmenistan; 4) F. tularensis subsp. novicida is of low virulence, isolated in USA, Canada, Spain and Australia; 5) F. tularensis subsp. philomiragia, is of low virulence, associated with salt water (Atlantic, Mediterranean). Tularemia is very rear in Macedonia, but in 1996 an

  12. As lendas e a imaginação simbólica: uma metodologia para a sala de aula (The legends and symbolic imagination: a methodology for the classroom. DOI: 10.5752/P.2175-5841.2012v10n26p538

    Directory of Open Access Journals (Sweden)

    Eunice Simões Lins Gomes

    2012-07-01

    Full Text Available Entendemos que nenhuma sociedade constrói o presente e alicerça o futuro sem compreender sua cultura e sem conhecer o significado de sua história. O objetivo deste artigo consiste em apresentar uma metodologia aplicada na sala de aula das primeiras séries do ensino fundamental, cujo propósito foi despertar a imaginação simbólica dos alunos através do uso das lendas presentes nos livros didáticos do ensino religioso ministradas pelos docentes. Os temas estudados têm como base teórica a fenomenologia da religião, a antropologia e a teoria geral do imaginário. Selecionamos para nosso estudo como fundamentação metodológica a pesquisa descritiva, de campo e a abordagem qualitativa para análise dos dados. Ponderamos que a pesquisa descritiva observa, registra, analisa e correlaciona fatos ou fenômenos sem manipulá-los, ela procura descobrir, com precisão possível, a frequência com que um fenômeno ocorre, sua relação e conexão com outros, sua natureza e característica. Nos primeiros resultados de nossa investigação cientifica foi identificado que as lendas trabalhadas na sala de aula potencializam o imaginário popular resguardando a identidade cultural de uma manifestação religiosa. Consideramos que esta metodologia de ensino proposta pode ser implantada pelos professores do ensino religioso no seu planejamento. Palavravas-chave: Lendas. Imaginação. Educação.   Abstract No society is able to build the present and set the bases for the future without understanding its culture and without knowing the meaning of its history. The purpose of this article is to present the methodology put into practice in the classrooms of the first grades of the elementary school, which have the sole intention to wake up the symbolic imagination of the students through the use of the legends found in the didactic books of the religious teaching ministered by the faculty members. The topics studied are based upon the religious

  13. Panel: Methodologies for multi-agent systems

    NARCIS (Netherlands)

    Kinny, David; Treur, Jan; Gasser, Les; Clark, Steve; Müller, Jörg

    1998-01-01

    Multi-Agent Systems technologies are migrating from research labs to software engineering centres. If these technologies are to realize their potential, it will become increasingly important to develop and employ methodologies, accessible to software engineers, for specifying, analysing, designing,

  14. A Highly Secure Mobile Agent System Architecture

    Science.gov (United States)

    Okataku, Yasukuni; Okutomi, Hidetoshi; Yoshioka, Nobukazu; Ohgishi, Nobuyuki; Honiden, Shinichi

    We propose a system architecture for mobile agents to improve their security in the environments of insecure networks and non-sophisticated terminals such as PDAs. As mobile agents freely migrate onto their favorite terminals through insecure networks or terminals, it is not appropriate for them to store some secret information for authentication and encryption/decryption. We introduce one and more secure nodes(OASIS NODE) for securely generating and verifying authentication codes. The each agent’s data are encrypted by a pseudo-chaos cipher mechanism which doesn’t need any floating processing co-processor. We’ve constructed a prototype system on a Java mobile agent framework, “Bee-gent" which implements the proposed authentication and cipher mechanisms, and evaluated their performances and their applicability to business fields such as an auction system by mobile agents.

  15. Agent-based modeling of sustainable behaviors

    CERN Document Server

    Sánchez-Maroño, Noelia; Fontenla-Romero, Oscar; Polhill, J; Craig, Tony; Bajo, Javier; Corchado, Juan

    2017-01-01

    Using the O.D.D. (Overview, Design concepts, Detail) protocol, this title explores the role of agent-based modeling in predicting the feasibility of various approaches to sustainability. The chapters incorporated in this volume consist of real case studies to illustrate the utility of agent-based modeling and complexity theory in discovering a path to more efficient and sustainable lifestyles. The topics covered within include: households' attitudes toward recycling, designing decision trees for representing sustainable behaviors, negotiation-based parking allocation, auction-based traffic signal control, and others. This selection of papers will be of interest to social scientists who wish to learn more about agent-based modeling as well as experts in the field of agent-based modeling.

  16. Trial of a New Antirheumatic Agent

    African Journals Online (AJOL)

    1974-05-04

    aspirin) and placebo in 10 outpatients with active rheumatoid arthritis, is reported. Both fenoprofen and aspirin were found to be similarly effective agents in rheumatoid arthritis with an average daily dose of 2,1 g fenoprofen ...

  17. Intelligent agents in data-intensive computing

    CERN Document Server

    Correia, Luís; Molina, José

    2016-01-01

    This book presents new approaches that advance research in all aspects of agent-based models, technologies, simulations and implementations for data intensive applications. The nine chapters contain a review of recent cross-disciplinary approaches in cloud environments and multi-agent systems, and important formulations of data intensive problems in distributed computational environments together with the presentation of new agent-based tools to handle those problems and Big Data in general. This volume can serve as a reference for students, researchers and industry practitioners working in or interested in joining interdisciplinary work in the areas of data intensive computing and Big Data systems using emergent large-scale distributed computing paradigms. It will also allow newcomers to grasp key concepts and potential solutions on advanced topics of theory, models, technologies, system architectures and implementation of applications in Multi-Agent systems and data intensive computing. .

  18. Matching Conflicts: Functional Validation of Agents

    National Research Council Canada - National Science Library

    Cybenko, George; Jiang, Guofei

    1999-01-01

    .... A broker or matchmaker service is often proposed as a solution. These systems use keywords drawn from application domain ontologies to specify agent services, usually framed within some sort of knowledge representation language...

  19. Competing intelligent search agents in global optimization

    Energy Technology Data Exchange (ETDEWEB)

    Streltsov, S.; Vakili, P. [Boston Univ., MA (United States); Muchnik, I. [Rutgers Univ., Piscataway, NJ (United States)

    1996-12-31

    In this paper we present a new search methodology that we view as a development of intelligent agent approach to the analysis of complex system. The main idea is to consider search process as a competition mechanism between concurrent adaptive intelligent agents. Agents cooperate in achieving a common search goal and at the same time compete with each other for computational resources. We propose a statistical selection approach to resource allocation between agents that leads to simple and efficient on average index allocation policies. We use global optimization as the most general setting that encompasses many types of search problems, and show how proposed selection policies can be used to improve and combine various global optimization methods.

  20. Penetratin and derivatives acting as antifungal agents

    NARCIS (Netherlands)

    Masman, Marcelo F.; Rodriguez, Ana M.; Raimondi, Marcela; Zacchino, Susana A.; Luiten, Paul G. M.; Somlai, Csaba; Kortvelyesi, Tamas; Penke, Botond; Enriz, Ricardo D.

    The synthesis, in vitro evaluation, and conformational study of RQIKTWFQNRRMKWKK-NH(2) (penetratin) and related derivatives acting as antifungal agents are reported. Penetratin and some of its derivatives displayed antifungal activity against the human opportunistic pathogenic standardized ATCC

  1. Agendas for Multi-Agent Learning

    National Research Council Canada - National Science Library

    Gordon, Geoffrey J

    2006-01-01

    .... Finally, we conclude with an example: starting from an informally-specified multi-agent learning problem, we illustrate how one might formalize and solve it by stepping through the tasks of modelling, design, and learning...

  2. AORTA: Adding Organizational Reasoning to Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Dignum, Virginia

    2014-01-01

    Open systems are characterized by a diversity of heterogeneous and autonomous agents that act according to private goals, and with a behavior that is hard to predict. They can be regulated through organizations similar to human organizations, which regulate the agents’ behavior space and describe...... the expected behavior of the agents. Agents need to be able to reason about the regulations, so that they can act within the expected boundaries and work towards the objectives of the organization. This extended abstract introduces AORTA, a component that can be integrated into agents’ reasoning mechanism......, allowing them to reason about (and act upon) regulations specified by an organizational model using simple reasoning rules. The added value is that the organizational model is independent of that of the agents, and that the approach is not tied to a specific organizational model....

  3. BODIPY derivatives as molecular photoacoustic contrast agents

    Science.gov (United States)

    Laoui, Samir; Bag, Seema; Dantiste, Olivier; Frenette, Mathieu; Hatamimoslehabadi, Maryam; Bellinger-Buckley, Stephanie; Tseng, Jen-Chieh; Rochford, Jonathan; Yelleswarapu, Chandra

    2014-03-01

    Photoacoustic imaging (PAI) is emerging as a key in vivo imaging technique. Endogenous contrast agents alone are insufficient to obtain high contrast images necessitating a need for synthetic exogenous contrast agents. In recent years a great deal of research has been devoted to the development of nanoparticle based contrast agents with little effort on molecular systems. Here we report on the design and evaluation of BODIPY inspired molecular photoacoustic contrast agents (MPACs). Through chemical modification of the established BODIPY fluorophore, increasing its vibrational freedom and appending with non-emissive functionalities, it is demonstrated that the S0-S1 absorbed excitation energy is redirected towards a nonradiative excited-state decay pathway. Optical and photoacoustic characterization of the modified BODIPY MPACs demonstrates a stronger photoacoustic signal compared to the corresponding fluorescent BODIPY probes.

  4. Paramecium tetraurelia: prescreen for hazardous agents

    Energy Technology Data Exchange (ETDEWEB)

    Smith-Sonneborn, J.; Herr, C.; VanKirk, E.

    1979-01-01

    The ciliated protozoan, paramecia, is proposed as a eukaryote model system for use in short-term screening assays for detection of mutagenic/carcinogenic and hazardous agents. The approach utilizes two assays: the mutagenic and photodynamic systems.

  5. Veterans and agent orange: update 2000

    National Research Council Canada - National Science Library

    Division of Health Promotion and Disease Prevention Staff; Institute of Medicine, Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides

    2001-01-01

    Veterans and Agent Orange: Update 2000 examines the state of the scientific evidence regarding associations between diseases and exposure to dioxin and other chemical compounds in herbicides used in Vietnam...

  6. Ulipristal acetate as an emergency contraceptive agent.

    Science.gov (United States)

    Martinez, Alan M; Thomas, Michael A

    2012-09-01

    Emergency contraceptive agents play a crucial role in preventing unplanned pregnancy. These agents and devices have been studied since the 1960s and have had varied results in terms of side effects and efficacy. A new oral tablet for emergency contraception (EC), ulipristal acetate (UPA) , is a selective progesterone receptor modulator and can be used up to 120 h following unprotected intercourse, without an increase in adverse effects or a decrease in efficacy. This article reviews studies that evaluate the pharmacodynamics, pharmacokinetics, clinical efficacy, and safety profile of UPA as an emergency contraceptive agent. UPA, a selective progesterone receptor modulator, is administered as a single 30 mg dose for EC. This agent provides a comparable, if not better, efficacy and side effect profile than seen with levonorgestrel or mifepristone. Because it has both agonistic and antagonistic effects on the progesterone receptor, ongoing clinical trials are documenting UPA's use for patients with endometriosis and as an extended use contraceptive.

  7. Spions as nano-theranostics agents

    CERN Document Server

    Zarepour, Atefeh; Khosravi, Arezoo

    2017-01-01

    This Brief introduces SuperParamagnetic Iron Oxide Nanoparticles (SPIONs), the different synthesis approaches, their applications in the field of diagnostics and treatment and finally as theranostic agents in cancer.

  8. Argumentation and Multi-Agent Decision Making

    OpenAIRE

    Parsons, S; Jennings, NR

    1998-01-01

    This paper summarises our on-going work on mixed- initiative decision making which extends both classical decision theory and a symbolic theory of decision making based on argumentation to a multi-agent domain.

  9. Sanguinarine: A Novel Agent Against Prostate Cancer

    National Research Council Canada - National Science Library

    Ahmad, Nihal

    2007-01-01

    ..., has been shown to possess anti-microbial, antioxidant and anti-inflammatory properties. Our earlier studies suggested that sanguinarine may be developed as an agent for the management of prostate cancer...

  10. Sanguinarine: A Novel Agent Against Prostate Cancer

    National Research Council Canada - National Science Library

    Ahmad, Nihal

    2008-01-01

    ..., has been shown to possess anti-microbial, antioxidant and anti-inflammatory properties. Our earlier studies suggested that sanguinarine may be developed as an agent for the management of prostate cancer...

  11. Nominaliseeritud protsessi agent meediauudistes / Reet Kasik

    Index Scriptorium Estoniae

    Kasik, Reet, 1946-

    2006-01-01

    Ajalehe "Postimees" 2005. aasta materjalile toetudes vaadeldakse, mis tüüpi on nominalisatsioonides representeeritavad protsessid ja mis kujul on esitatud protsessi agent ehk tegija. Aluseks on võetud funktsionaalse grammatika põhimõtted.

  12. Radioiodination of methoxsalen using different iodinating agents

    International Nuclear Information System (INIS)

    Ayyoub, S.M.; Farah, K.

    2007-01-01

    Different iodinating agents such as chloramine-T (Ch-T), iodogen, H 2 O 2 and N-bromosuccinimide (NBS) were used for the labelling of methoxsalen via electrophilic substitution reaction. These iodinating agents oxidize NaI to produce the iodonium ions which attacked the active position in methoxsalen. These iodinating agents successfully iodinate the methoxsalen with a reasonable radiochemical yield and purity. The factors affecting both chemical yield and purity, such as the concentration of the iodinating agent, the methoxsalen concentration and the reaction time, were studied. Different developing solvents were used for the identification of the products using TLC technique. It was found that the most suitable solvent for the identification of methoxsalen using TLC was n-butanol : acetic acid : water (4:1:1). Radiochemical yields of 80% and 84% , with purity 99%, were achieved in case of NBS and H 2 O 2 , respectively

  13. Contrast Agent in Magnetic Resonance Imaging

    DEFF Research Database (Denmark)

    Vu-Quang, Hieu

    2015-01-01

    Nanoparticles have been employed as contrast agent in magnetic resonance imaging (MRI) in order to improve sensitivity and accuracy in diagnosis. In addition, these contrast agents are potentially combined with other therapeutic compounds or near infrared bio-imaging (NIR) fluorophores to obtain...... theranostic or dual imaging purposes, respectively. There were two main types of MRI contrast agent that were synthesized during this PhD project including fluorine containing nanoparticles and magnetic nanoparticles. In regard of fluorine containing nanoparticles, there were two types contrast agent...... that were synthesized in project I and II. In project I, Poly (lactic-co-glycolic acid)-block-poly (ethylene glycol)-Folate Pefluorooctyl Bromide/Indocyanine green/ Doxorubicin (PLGA-PEG-Folate PFOB/ICG/Dox) has been formulated for the dual imaging NIR and 19F MRI as well as in the combination of Dox...

  14. Behavioural domain knowledge transfer for autonomous agents

    CSIR Research Space (South Africa)

    Rosman, Benjamin S

    2014-11-01

    Full Text Available , and Behavior Transfer in Autonomous Robots, AAAI 2014 Fall Symposium Series, 13-15 November 2014 Behavioural Domain Knowledge Transfer for Autonomous Agents Benjamin Rosman Mobile Intelligent Autonomous Systems Modelling and Digital Science Council...

  15. Agent chameleons: moving minds from robots to digital information spaces

    OpenAIRE

    O'Hare, G. M. P. (Greg M. P.); Duffy, Brian R.; Bradley, John F.; Martin, A. (Alan)

    2003-01-01

    Agent Chameleons investigates the motivation, desire and possibility of agent migration and mutation between real and artificial spaces. The agent must be able to mutate and change its form and function depending upon the environment within which it is situated. The form inextricably dictates or constrains its behaviour and capabilities. This paper introduces the Agent Chameleon Architecture which supports agent migration and mutation.

  16. inventory management, VMI, software agents, MDV model

    Directory of Open Access Journals (Sweden)

    Waldemar Wieczerzycki

    2012-03-01

    Full Text Available Background: As it is well know, the implementation of instruments of logistics management is only possible with the use of the latest information technology. So-called agent technology is one of the most promising solutions in this area. Its essence consists in an entirely new way of software distribution on the computer network platform, in which computer exchange among themselves not only data, but also software modules, called just agents. The first aim is to propose the alternative method of the implementation of the concept of the inventory management by the supplier with the use of intelligent software agents, which are able not only to transfer the information but also to make the autonomous decisions based on the privileges given to them. The second aim of this research was to propose a new model of a software agent, which will be both of a high mobility and a high intelligence. Methods: After a brief discussion of the nature of agent technology, the most important benefits of using it to build platforms to support business are given. Then the original model of polymorphic software agent, called Multi-Dimensionally Versioned Software Agent (MDV is presented, which is oriented on the specificity of IT applications in business. MDV agent is polymorphic, which allows the transmission through the network only the most relevant parts of its code, and only when necessary. Consequently, the network nodes exchange small amounts of software code, which ensures high mobility of software agents, and thus highly efficient operation of IT platforms built on the proposed model. Next, the adaptation of MDV software agents to implementation of well-known logistics management instrument - VMI (Vendor Managed Inventory is illustrated. Results: The key benefits of this approach are identified, among which one can distinguish: reduced costs, higher flexibility and efficiency, new functionality - especially addressed to business negotiation, full automation

  17. Agent tracking: a psycho-historical theory of the identification of living and social agents.

    Science.gov (United States)

    Bullot, Nicolas J

    To explain agent-identification behaviours, universalist theories in the biological and cognitive sciences have posited mental mechanisms thought to be universal to all humans, such as agent detection and face recognition mechanisms. These universalist theories have paid little attention to how particular sociocultural or historical contexts interact with the psychobiological processes of agent-identification. In contrast to universalist theories, contextualist theories appeal to particular historical and sociocultural contexts for explaining agent-identification. Contextualist theories tend to adopt idiographic methods aimed at recording the heterogeneity of human behaviours across history, space, and cultures. Defenders of the universalist approach tend to criticise idiographic methods because such methods can lead to relativism or may lack generality. To overcome explanatory limitations of proposals that adopt either universalist or contextualist approaches in isolation, I propose a philosophical model that integrates contributions from both traditions: the psycho-historical theory of agent-identification. This theory investigates how the tracking processes that humans use for identifying agents interact with the unique socio-historical contexts that support agent-identification practices. In integrating hypotheses about the history of agents with psychological and epistemological principles regarding agent-identification, the theory can generate novel hypotheses regarding the distinction between recognition-based, heuristic-based, and explanation-based agent-identification.

  18. Disease Modifying Agents for Multiple Sclerosis

    OpenAIRE

    Hilas, Olga; Patel, Priti N; Lam, Sum

    2010-01-01

    Objective: To summarize major clinical trials which evaluate the efficacy and safety data of approved disease modifying agents for the treatment of various types of multiple sclerosis. Data Sources: A MEDLINE (1966 to August 2008) search of clinical trials using the terms multiple sclerosis, interferon, glatiramer, mitoxantrone and natalizumab was performed. A manual bibliographic search was also conducted. English-language articles identified from the searches were evaluated. New agents unde...

  19. New Safety rule for Chemical Agents

    CERN Multimedia

    Safety Commission

    2010-01-01

    The following Safety rule has been issued on 08-01-2010: Safety Regulation SR-C Chemical Agents This document applies to all persons under the Director General’s authority. It sets out the minimal requirements for the protection of persons from risks to their safety and health arising, or likely to arise, from the effects of hazardous chemical agents used in any CERN activity. All Safety rules are available on the web pages.

  20. Non-toxic brominated perfluorocarbons radiopaque agents

    International Nuclear Information System (INIS)

    Long, D.M. Jr.

    1976-01-01

    Non-toxic bromofluorocarbon radiopaque agents are disclosed. Certain monobrominated acyclic fluorocarbons, e.g., CF 3 (CF 2 ) 6 CF 2 Br, are improved non-toxic radiopaque agents useful in diagnostic roentgenology, for example in visualizing the gastrointestinal tract, the tracheobronchial tree, the alveolar spaces or parenchyma of the lung, the spleen, the urinary bladder and ureters, the common bile duct and its radicals, the pancreatic ducts, the blood vessels, etc. 13 claims, no drawings

  1. Institutions, Behavior of Agents and Efficiency

    Directory of Open Access Journals (Sweden)

    Sukharev Oleg, S.

    2016-03-01

    Full Text Available We study the efficiency criterion, describing the behavior and choices of agents, the influence of moral norms on the model of behavior, as well as the criterion of efficiency as an institution to assess the behavior and development of the economic system. Curve proposed institutional compromise that allows to determine the possibility of changes in the welfare of interacting agents and their compliance with ethical standards when welfare increases due to violation or compliance with these standards. For the purposes of this demonstration of the influence of the model of chart-based dilemmas Holmes-Moriarty. Incentives in determining the agents behaviors play a key role in their formation due to the moral principles of behavior. However, in economics there are situations when moral principles are derived certain behaviors or interactions agents. Holmes and Moriarty there is an alternative interaction, which they can not take advantage of, and there is a full range of alternatives that actually programs the strategic outcomes of interactions that reflect the curves of "institutional compromise." Choosing an agent of moral standards as a potential model determines its behavior and, most importantly, interaction with other agents, adhering to certain moral principles. Assess the condition and the possibility of using a static criterion of Pareto efficiency for the analysis of situations where it is important to measure the economic efficiency. Showing institutional aspects that must be considered in the application or formulation of new performance criteria. It is proved that there is a connection microeconomic efficiency / inefficiency and parameters of behavior of agents that actualizes the need to impact on the behavior of agents incentives to solve the task of changing the structure.

  2. Multiobjective Genetic Programming of Agent Decision Strategies

    OpenAIRE

    Šlapák, M.; Neruda, R. (Roman)

    2014-01-01

    This work describes a method to control a behaviour of intelligent data mining agent We developed an adaptive decision making system that utilizes genetic programming technique to evolve an agent’s decision strategy. The parameters of data mining task and current state of an agent are taken into account by tree structures evolved by genetic programming. Efficiency of decision strategies is compared from the perspectives of single and multi criteria optimization.

  3. Bacteriophages as recognition and identification agents

    International Nuclear Information System (INIS)

    Teodorescu, M.C.; Gaspar, Alexandre.

    1987-01-01

    Bacteriophages are employed as agents for recognition and identification of molecules and cellular materials, using their ability to recognize their bacterial host, by coating them with antibodies or by selecting them to perform in a manner analogous to antibodies. Visibility for identification is effected by incorporating a fluorescent agent, a radioisotope, a metal, an enzyme, or other staining material. The method of this invention may be utilized in selected clinical procedures, and is adaptable to use in an assay kit. (author)

  4. Quantum decision making by social agents

    OpenAIRE

    V. I. Yukalov; D. Sornette

    2012-01-01

    The influence of additional information on the decision making of agents, who are interacting members of a society, is analyzed within the mathematical framework based on the use of quantum probabilities. The introduction of social interactions, which influence the decisions of individual agents, leads to a generalization of the quantum decision theory developed earlier by the authors for separate individuals. The generalized approach is free of the standard paradoxes of classical decision th...

  5. A Estreptozootocina Como Agente Diabetogênico

    OpenAIRE

    Furlan, Maria Montserrat Diaz Pedrosa

    2008-01-01

    Os quadros experimentais de diabetes mellitus permitem observar as diversas variáveis envolvidas na fisiopatologia desta doença sob condições controladas. Entretanto, conhecer as características do agente químico usado na indução do diabetes é importante para uma análise coerente dos resultados obtidos. Esta revisão apresenta aspectos relacionados à estreptozootocina, um agente diabetogênico amplamente u...

  6. Towards Culturally-Aware Virtual Agent Systems

    DEFF Research Database (Denmark)

    Endrass, Birgit; André, Elisabeth; Rehm, Matthias

    2010-01-01

    Globalization leads to an increase in intercultural encounters with a risk of misunderstandings due to different patterns of behavior and understanding. Learning applications have been proposed that employ virtual agents as their primary tool. Through their embodiment, learning can be done in a g...... of the art that integrates culture in multiagent systems. In addition, an approach of simulating culture-specific behavior using such a multiagent system is introduced and future trends in enculturating virtual agent systems are outlined....

  7. Tissue-specific MR contrast agents

    Energy Technology Data Exchange (ETDEWEB)

    Weinmann, Hanns-Joachim E-mail: hannsjoachim.weinmann@schering.de; Ebert, Wolfgang; Misselwitz, Bernd; Schmitt-Willich, Heribert

    2003-04-01

    The purpose of this review is to outline recent trends in contrast agent development for magnetic resonance imaging. Up to now, small molecular weight gadolinium chelates are the workhorse in contrast enhanced MRI. These first generation MR contrast agents distribute into the intravascular and interstitial space, thus allowing the evaluation of physiological parameters, such as the status or existence of the blood-brain-barrier or the renal function. Shortly after the first clinical use of paramagnetic metallochelates in 1983, compounds were suggested for liver imaging and enhancing a cardiac infarct. Meanwhile, liver specific contrast agents based on gadolinium, manganese or iron become reality. Dedicated blood pool agents will be available within the next years. These gadolinium or iron agents will be beneficial for longer lasting MRA procedures, such as cardiac imaging. Contrast enhanced lymphography after interstitial or intravenous injection will be another major step forward in diagnostic imaging. Metastatic involvement will be seen either after the injection of ultrasmall superparamagnetic iron oxides or dedicated gadolinium chelates. The accumulation of both compound classes is triggered by an uptake into macrophages. It is likely that similar agents will augment MRI of atheriosclerotic plaques, a systemic inflammatory disease of the arterial wall. Thrombus-specific agents based on small gadolinium labeled peptides are on the horizon. It is very obvious that the future of cardiovascular MRI will benefit from the development of new paramagnetic and superparamagnetic substances. The expectations for new tumor-, pathology- or receptor-specific agents are high. However, is not likely that such a compound will be available for daily routine MRI within the next decade.

  8. Agent Argumentation with Opinions and Advice

    Science.gov (United States)

    Debenham, John; Sierra, Carles

    In argumentation-based negotiation the rhetorical illocutionary particles Appeals, Rewards and Threats have implications for the players that extend beyond a single negotiation and are concerned with building (business) relationships. This paper extends an agent's relationship-building argumentative repertoire with Opinions and Advice. A framework is described that enables agents to model their relationships and to use argumentative dialogue strategically both to achieve good negotiation outcomes and to build and sustain valuable relationships.

  9. A multi-agent based cell controller

    OpenAIRE

    Paulo Leitão; Francisco José de Oliveira Restivo; Goran Putnik

    2001-01-01

    This paper discusses the opportunity to use multi-agents technology in automation and distributed manufacturing systems and the expected improvements. To support the discussion, it is described a manufacturing cell control application developed using the multi-agent technology, and the results are compared with other control application developed in the past by some of the authors, using a traditional approach, for the same flexible manufacturing cell.

  10. Ontologies, Agents and the Grid: An Overview

    OpenAIRE

    Drozdowicz, Michal; Ganzha, Maria; Paprzycki, Marcin; Olejnik, Richard; Lirkov, Ivan; Telegin, P.; Senobari, M.

    2009-01-01

    23 pages; One of the important claims that permeate the current view of information management is that ontological demarcation of data and semantic information processing are going to allow us to infuse "intelligence" into information systems. Separately, it is claimed that software agents, combined with ontologies will be the foundation ofWeb 4.0. In our work we are developing an agent-team-based resource management and brokering infrastructure for computational grids. The proposed meta-leve...

  11. Reaching High Interactive Levels with Situated Agents

    Directory of Open Access Journals (Sweden)

    Guzmán-Obando J.

    2013-01-01

    Full Text Available El documento presenta un proceso coordinado a través del cual los agentes situados son capaces de trabajar en forma conjunta con el conocimiento de sus habilidades para interactuar con otras entidades similares. Una buena coordinación se deriva de que cada agente situado es capaz de representar sus tasas de idoneidad para llevar a cabo cualquier acción de una manera eficaz. Además de utilizar dichas tasas, un agente puede coordinar sus acciones con otros agentes. En este sentido, cada agente situado trata de seleccionar y realizar sólo las acciones con los mayores índices de ejecución. Algunos experimentos en un verdadero fútbol robótico banco de pruebas están diseñadas para poner en práctica el enfoque coordinado propuesto. Observaciones finales concluir la eficacia y las ventajas de la obra presentada con el fin de aumentar el rendimiento de un equipo integrado por agentes situados cuando tienen que resolver tareas complejas en un escenario dinámico, competitivo e impredecible.

  12. CHI: A General Agent Communication Framework

    Energy Technology Data Exchange (ETDEWEB)

    Goldsmith, S.Y.; Phillips, L.R.; Spires, S.V.

    1998-12-17

    We have completed and exercised a communication framework called CHI (CLOS to HTML Interface) by which agents can communicate with humans. CHI follows HTTP (HyperText Transfer Protocol) and produces HTML (HyperText Markup Language) for use by WWW (World-Wide Web) browsers. CHI enables the rapid and dynamic construction of interface mechanisms. The essence of CHI is automatic registration of dynamically generated interface elements to named objects in the agent's internal environment. The agent can access information in these objects at will. State is preserved, so an agent can pursue branching interaction sequences, activate failure recovery behaviors, and otherwise act opportunistically to maintain a conversation. The CHI mechanism remains transparent in multi-agent, multi-user environments because of automatically generated unique identifiers built into the CHI mechanism. In this paper we discuss design, language, implementation, and extension issues, and, by way of illustration, examine the use of the general CHI/HCHI mechanism in a specific international electronic commerce system. We conclude that the CHI mechanism is an effective, efficient, and extensible means of the agent/human communication.

  13. History of chemical and biological warfare agents

    International Nuclear Information System (INIS)

    Szinicz, L.

    2005-01-01

    Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents

  14. History of chemical and biological warfare agents.

    Science.gov (United States)

    Szinicz, L

    2005-10-30

    Chemical and biological warfare agents constitute a low-probability, but high-impact risk both to the military and to the civilian population. The use of hazardous materials of chemical or biological origin as weapons and for homicide has been documented since ancient times. The first use of chemicals in terms of weapons of mass destruction goes back to World War I, when on April 22, 1915 large amounts of chlorine were released by German military forces at Ypres, Belgium. Until around the 1970s of the 20th century, the awareness of the threat by chemical and biological agents had been mainly confined to the military sector. In the following time, the development of increasing range delivery systems by chemical and biological agents possessors sensitised public attention to the threat emanating from these agents. Their proliferation to the terrorists field during the 1990s with the expanding scale and globalisation of terrorist attacks suggested that these agents are becoming an increasing threat to the whole world community. The following article gives a condensed overview on the history of use and development of the more prominent chemical and biological warfare agents.

  15. Intelligent agents for e-commerce applications

    Science.gov (United States)

    Vuppala, Krishna

    1999-12-01

    This thesis focuses on development of intelligent agent solutions for e-commerce applications. E-Commerce has several complexities like: lack of information about the players, learning the nature of one's business partners/competitors, finding the right business partner to do business with, using the right strategy to get best profit out of the negotiations etc. The agent models developed can be used in any agent solution for e-commerce. Concepts and techniques from Game Theory and Artificial Intelligence are used. The developed models have several advantages over the existing ones as: the models assume the non-availability of information about other players in the market, the models of players get updated over the time as and when new information comes about the players, the negotiation model incorporates the patience levels of the players and expectations from other players in the market. Power industry has been chosen as the application area for the demonstration of the capabilities and usage of the developed agent models. Two e-commerce scenarios where sellers and buyers can go through the power exchanges to bid in auctions, or make bilateral deals outside of the exchange are addressed. In the first scenario agent helps market participants in coordinating strategies with other participants, bidding in auctions by analyzing and understanding the behavior of other participants. In the second scenario, called "Power Traders Assistant" agent helps power trader, who buys and sells power through bilateral negotiations, in negotiating deals with his customers.

  16. Unibot, a Universal Agent Architecture for Robots

    Directory of Open Access Journals (Sweden)

    Saša Mladenović

    2017-01-01

    Full Text Available Today there are numerous robots in different applications domains despite the fact that they still have limitations in perception, actuation and decision process. Consequently, robots usually have limited autonomy, they are domain specific or have difficulty to adapt on new environments. Learning is the property that makes an agent intelligent and the crucial property that a robot should have to proliferate into the human society. Embedding the learning ability into the robot may simplify the development of the robot control mechanism. The motivation for this research is to develop the agent architecture of the universal robot – Unibot. In our approach the agent is the robot i.e. Unibot that acts in the physical world and is capable of learning. The Unibot conducts several simultaneous simulations of a problem of interest like path-finding. The novelty in our approach is the Multi-Agent Decision Support System which is developed and integrated into the Unibot agent architecture in order to execute simultaneous simulations. Furthermore, the Unibot calculates and evaluates between multiple solutions, decides which action should be performed and performs the action. The prototype of the Unibot agent architecture is described and evaluated in the experiment supported by the Lego Mindstorms robot and the NetLogo.

  17. Using Cognitive Agents to Train Negotiation Skills

    Directory of Open Access Journals (Sweden)

    Christopher A. Stevens

    2018-02-01

    Full Text Available Training negotiation is difficult because it is a complex, dynamic activity that involves multiple parties. It is often not clear how to create situations in which students can practice negotiation or how to measure students' progress. Some have begun to address these issues by creating artificial software agents with which students can train. These agents have the advantage that they can be “reset,” and played against multiple times. This allows students to learn from their mistakes and try different strategies. However, these agents are often based on normative theories of how negotiators should conduct themselves, not necessarily how people actually behave in negotiations. Here, we take a step toward addressing this gap by developing an agent grounded in a cognitive architecture, ACT-R. This agent contains a model of theory-of-mind, the ability of humans to reason about the mental states of others. It uses this model to try to infer the strategy of the opponent and respond accordingly. In a series of experiments, we show that this agent replicates some aspects of human performance, is plausible to human negotiators, and can lead to learning gains in a small-scale negotiation task.

  18. Agent-based modeling and network dynamics

    CERN Document Server

    Namatame, Akira

    2016-01-01

    The book integrates agent-based modeling and network science. It is divided into three parts, namely, foundations, primary dynamics on and of social networks, and applications. The book begins with the network origin of agent-based models, known as cellular automata, and introduce a number of classic models, such as Schelling’s segregation model and Axelrod’s spatial game. The essence of the foundation part is the network-based agent-based models in which agents follow network-based decision rules. Under the influence of the substantial progress in network science in late 1990s, these models have been extended from using lattices into using small-world networks, scale-free networks, etc. The book also shows that the modern network science mainly driven by game-theorists and sociophysicists has inspired agent-based social scientists to develop alternative formation algorithms, known as agent-based social networks. The book reviews a number of pioneering and representative models in this family. Upon the gi...

  19. An Interactive Tool for Creating Multi-Agent Systems and Interactive Agent-based Games

    DEFF Research Database (Denmark)

    Lund, Henrik Hautop; Pagliarini, Luigi

    2011-01-01

    Utilizing principles from parallel and distributed processing combined with inspiration from modular robotics, we developed the modular interactive tiles. As an educational tool, the modular interactive tiles facilitate the learning of multi-agent systems and interactive agent-based games....... The modular and physical property of the tiles provides students with hands-on experience in exploring the theoretical aspects underlying multi-agent systems which often appear as challenging to students. By changing the representation of the cognitive challenging aspects of multi-agent systems education...... to a physical (hands-on) one, the challenge may become much easier and fun to face for the students....

  20. Agents applied in health care: A review.

    Science.gov (United States)

    Isern, David; Sánchez, David; Moreno, Antonio

    2010-03-01

    The agent-oriented paradigm has emerged as a viable approach for the development of autonomic systems in the healthcare domain. This paper reviews representative works in this area in order to identify the main research lines and study their level of applicability. Moreover, from the analysis of those works and the authors' own experiences, some lines of future research are suggested. This paper presents a review of the literature (2002-2008) of applications of agents in healthcare collected from medical databases as well as international conferences. 15 agent-based systems were selected according to a set of criteria of work relevancy. Their internal architecture as well as communication-based coordination techniques were reviewed. A classification considering the main goal of the systems has been made. For each category, a discussion of the suitability of agent technology in resolving healthcare problems is presented. Agent-based systems offer added values over classical software approaches (e.g., reusability, reliability, flexibility, robustness, maintainability and adaptability). Furthermore, agent technology supports the integration of legacy systems, tackling the shortcomings of centralised systems, such as performance bottlenecks, resource limitations, and different kinds of failures. During the review, we found a huge number of contributions in this area, showing a growing interest of researchers. However, most of the analysed systems are only prototypes, they are not widely deployed in real environments and they are difficult to extend to others domains. Several aspects (security, reusability, modularity, personalisation, system maintenance) should be studied carefully in the next years in order to bring agent technology to real settings. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  1. Environmental Agents Service (EAS) Registry System of Records

    Data.gov (United States)

    Department of Veterans Affairs — The Environmental Agent Service (EAS) Registries is the information system encompassing the Ionizing Radiation Registry (IRR), the Agent Orange Registry (AOR), and...

  2. 2015 Special Sessions of the 13th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Hernández, Josefa; Mathieu, Philippe; Campbell, Andrew; Fernández-Caballero, Antonio; Moreno, María; Julián, Vicente; Alonso-Betanzos, Amparo; Jiménez-López, María; Botti, Vicente; Trends in Practical Applications of Agents, Multi-Agent Systems and Sustainability : the PAAMS Collection

    2015-01-01

    This volume presents the papers that have been accepted for the 2015 special sessions of the 13th International Conference on Practical Applications of Agents and Multi-Agent Systems, held at University of Salamanca, Spain, at 3rd-5th June, 2015: Agents Behaviours and Artificial Markets (ABAM); Agents and Mobile Devices (AM); Multi-Agent Systems and Ambient Intelligence (MASMAI); Web Mining and Recommender systems (WebMiRes); Learning, Agents and Formal Languages (LAFLang); Agent-based Modeling of Sustainable Behavior and Green Economies (AMSBGE); Emotional Software Agents (SSESA) and Intelligent Educational Systems (SSIES). The volume also includes the paper accepted for the Doctoral Consortium in PAAMS 2015. PAAMS, the International Conference on Practical Applications of Agents and Multi-Agent Systems is an evolution of the International Workshop on Practical Applications of Agents and Multi-Agent Systems. PAAMS is an international yearly tribune to present, to discuss, and to disseminate the latest develo...

  3. Contrast agent choice for intravenous coronary angiography

    International Nuclear Information System (INIS)

    Zeman, H.D.; Siddons, D.P.

    1989-01-01

    The screening of the general population for coronary artery disease would be practical if a method existed for visualizing the extent of occlusion after an intravenous injection of contrast agent. Measurements performed with monochromatic synchrotron radiation x-rays and an iodine containing contrast agent at the Stanford Synchrotron Radiation Laboratory have shown that such an intravenous angiography procedure would be possible with an adequately intense monochromatic x-ray source. Because of the size and cost of synchrotron radiation facilities it would be desirable to make the most efficient use of the intensity available, while reducing as much as possible the radiation dose experienced by the patient. By choosing contrast agents containing elements with a higher atomic number than iodine, it is possible to both improve the image quality and reduce the patient radiation dose, while using the same synchrotron source. By using Si monochromator crystals with a small mosaic spread, it is possible to increase the x-ray flux available for imaging by over an order of magnitude, without any changes in the storage ring or wiggler magnet. The most critical imaging task for intravenous coronary angiography utilizing synchrotron radiation x-rays is visualizing a coronary artery through the left ventricle or aorta which also contains a contrast agent. Calculations have been made of the signal to noise ratio expected for this imaging task for various contrast agents with atomic numbers between that of iodine and bismuth

  4. Electrospun biodegradable polymers loaded with bactericide agents

    Directory of Open Access Journals (Sweden)

    Ramaz Katsarava

    2016-03-01

    Full Text Available Development of materials with an antimicrobial activity is fundamental for different sectors, including medicine and health care, water and air treatment, and food packaging. Electrospinning is a versatile and economic technique that allows the incorporation of different natural, industrial, and clinical agents into a wide variety of polymers and blends in the form of micro/nanofibers. Furthermore, the technique is versatile since different constructs (e.g. those derived from single electrospinning, co-electrospinning, coaxial electrospinning, and miniemulsion electrospinning can be obtained to influence the ability to load agents with different characteristics and stability and to modify the release behaviour. Furthermore, antimicrobial agents can be loaded during the electrospinning process or by a subsequent coating process. In order to the mitigate burst release effect, it is possible to encapsulate the selected drug into inorganic nanotubes and nanoparticles, as well as in organic cyclodextrine polysaccharides. In the same way, processes that involve covalent linkage of bactericide agents during surface treatment of electrospun samples may also be considered. The present review is focused on more recent works concerning the electrospinning of antimicrobial polymers. These include chitosan and common biodegradable polymers with activity caused by the specific load of agents such as metal and metal oxide particles, quaternary ammonium compounds, hydantoin compounds, antibiotics, common organic bactericides, and bacteriophages.

  5. Joint chemical agent detector (JCAD): the future of chemical agent detection

    Science.gov (United States)

    Laljer, Charles E.

    2003-08-01

    The Joint Chemical Agent Detector (JCAD) has continued development through 2002. The JCAD has completed Contractor Validation Testing (CVT) that included chemical warfare agent testing, environmental testing, electromagnetic interferent testing, and platform integration validation. The JCAD provides state of the art chemical warfare agent detection capability to military and homeland security operators. Intelligence sources estimate that over twenty countries have active chemical weapons programs. The spread of weapons of mass destruction (and the industrial capability for manufacture of these weapons) to third world nations and terrorist organizations has greatly increased the chemical agent threat to U.S. interests. Coupled with the potential for U.S. involvement in localized conflicts in an operational or support capacity, increases the probability that the military Joint Services may encounter chemical agents anywhere in the world. The JCAD is a small (45 in3), lightweight (2 lb.) chemical agent detector for vehicle interiors, aircraft, individual personnel, shipboard, and fixed site locations. The system provides a common detection component across multi-service platforms. This common detector system will allow the Joint Services to use the same operational and support concept for more efficient utilization of resources. The JCAD detects, identifies, quantifies, and warns of the presence of chemical agents prior to onset of miosis. Upon detection of chemical agents, the detector provides local and remote audible and visual alarms to the operators. Advance warning will provide the vehicle crew and other personnel in the local area with the time necessary to protect themselves from the lethal effects of chemical agents. The JCAD is capable of being upgraded to protect against future chemical agent threats. The JCAD provides the operator with the warning necessary to survive and fight in a chemical warfare agent threat environment.

  6. Smell Detection Agent Based Optimization Algorithm

    Science.gov (United States)

    Vinod Chandra, S. S.

    2016-09-01

    In this paper, a novel nature-inspired optimization algorithm has been employed and the trained behaviour of dogs in detecting smell trails is adapted into computational agents for problem solving. The algorithm involves creation of a surface with smell trails and subsequent iteration of the agents in resolving a path. This algorithm can be applied in different computational constraints that incorporate path-based problems. Implementation of the algorithm can be treated as a shortest path problem for a variety of datasets. The simulated agents have been used to evolve the shortest path between two nodes in a graph. This algorithm is useful to solve NP-hard problems that are related to path discovery. This algorithm is also useful to solve many practical optimization problems. The extensive derivation of the algorithm can be enabled to solve shortest path problems.

  7. Anabolic agents: what is beyond osteoporosis?

    Science.gov (United States)

    Liu, Y; Levack, A E; Marty, E; Or, O; Samuels, B P; Redko, M; Lane, J M

    2018-04-07

    Osteoporosis is a common skeletal disorder characterized by low bone mass, which leads to reduced bone strength and an increased risk of fractures. Anabolic agents have been shown to improve bone mass and decrease fracture risk in osteoporosis patients by directly stimulating osteoblasts to produce new bone. Currently, two anabolic agents are available in the USA: recombinantly produced teriparatide (TPTD), which is the fully active (1-34) amino active sequence of human parathyroid hormone (PTH), and abaloparatide (APTD), a synthetic analog of parathyroid hormone-related peptide (PTHrP). At present, both agents are approved only for treatment of patients with osteoporosis at high risk of fracture. Nonetheless, their anabolic properties have led to off-label application in additional settings which include spine fusion, osteonecrosis of the jaw, arthroplasty, and fracture healing. In this article, we summarize available scientific literature regarding the efficacy, effectiveness, and safety of TPTD in these off-label settings.

  8. Planning of Autonomous Multi-agent Intersection

    Directory of Open Access Journals (Sweden)

    Viksnin Ilya I.

    2016-01-01

    Full Text Available In this paper, we propose a traffic management system with agents acting on behalf autonomous vehicle at the crossroads. Alternatively to existing solutions based on usage of semiautonomous control systems with the control unit, proposed in this paper algorithm apply the principles of decentralized multi-agent control. Agents during their collaboration generate intersection plan and determinate the optimal order of road intersection for a given criterion based on the exchange of information about them and their environment. The paper contains optimization criteria for possible routes selection and experiments that perform in order to estimate the proposed model. Experiment results show that this model can significantly reduce traffic density compared to the traditional traffic management systems. Moreover, the proposed algorithm efficiency increases with road traffic density. Furthermore, the availability of control unit in the system significantly reduces the negative impact of possible failures and hacker attacks.

  9. Network Management using Multi-Agents System

    Directory of Open Access Journals (Sweden)

    Gustavo ISAZA

    2012-12-01

    Full Text Available This paper aims to present a multiagent system for network management. The models developed for the proposed system defines certain intelligent agents interact to achieve the objectives and requirements of the multiagent organization.These agents have the property of being adaptive, acquire knowledge and skills to make decisions according to the actual state of the network that is represented in the information base, MIB, SNMP devices. The ideal state of the network policy is defined by the end user entered, which contain the value that should have performance variables and other parameters such as the frequency with which these variables should be monitored.. An agent based architecture increase the integration, adaptability, cooperation, autonomy and the efficient operation in heterogeneous environment in the network supervision. 

  10. Network Management using Multi-Agents System

    Directory of Open Access Journals (Sweden)

    Nestor DUQUE

    2013-07-01

    Full Text Available This paper aims to present a multiagent system for network management. The models developed for the proposed system defines certain intelligent agents interact to achieve the objectives and requirements of the multiagent organization.These agents have the property of being adaptive, acquire knowledge and skills to make decisions according to the actual state of the network that is represented in the information base, MIB, SNMP devices. The ideal state of the network policy is defined by the end user entered, which contain the value that should have performance variables and other parameters such as the frequency with which these variables should be monitored.. An agent based architecture increase the integration, adaptability, cooperation, autonomy and the efficient operation in heterogeneous environment in the network supervision. 

  11. Anti-Infectious Agents against MRSA

    Directory of Open Access Journals (Sweden)

    Nobuhiro Koyama

    2012-12-01

    Full Text Available Clinically useful antibiotics, β-lactams and vancomycin, are known to inhibit bacterial cell wall peptidoglycan synthesis. Methicillin-resistant Staphylococcus aureus (MRSA has a unique cell wall structure consisting of peptidoglycan and wall teichoic acid. In recent years, new anti-infectious agents (spirohexaline, tripropeptin C, DMPI, CDFI, cyslabdan, 1835F03, and BPH-652 targeting MRSA cell wall biosynthesis have been discovered using unique screening methods. These agents were found to inhibit important enzymes involved in cell wall biosynthesis such as undecaprenyl pyrophosphate (UPP synthase, FemA, flippase, or UPP phosphatase. In this review, the discovery, the mechanism of action, and the future of these anti-infectious agents are described.

  12. Quantum Speedup for Active Learning Agents

    Directory of Open Access Journals (Sweden)

    Giuseppe Davide Paparo

    2014-07-01

    Full Text Available Can quantum mechanics help us build intelligent learning agents? A defining signature of intelligent behavior is the capacity to learn from experience. However, a major bottleneck for agents to learn in real-life situations is the size and complexity of the corresponding task environment. Even in a moderately realistic environment, it may simply take too long to rationally respond to a given situation. If the environment is impatient, allowing only a certain time for a response, an agent may then be unable to cope with the situation and to learn at all. Here, we show that quantum physics can help and provide a quadratic speedup for active learning as a genuine problem of artificial intelligence. This result will be particularly relevant for applications involving complex task environments.

  13. Microbial biofilms: biosurfactants as antibiofilm agents.

    Science.gov (United States)

    Banat, Ibrahim M; De Rienzo, Mayri A Díaz; Quinn, Gerry A

    2014-12-01

    Current microbial inhibition strategies based on planktonic bacterial physiology have been known to have limited efficacy on the growth of biofilm communities. This problem can be exacerbated by the emergence of increasingly resistant clinical strains. All aspects of biofilm measurement, monitoring, dispersal, control, and inhibition are becoming issues of increasing importance. Biosurfactants have merited renewed interest in both clinical and hygienic sectors due to their potential to disperse microbial biofilms in addition to many other advantages. The dispersal properties of biosurfactants have been shown to rival those of conventional inhibitory agents against bacterial and yeast biofilms. This makes them suitable candidates for use in new generations of microbial dispersal agents and for use as adjuvants for existing microbial suppression or eradication strategies. In this review, we explore aspects of biofilm characteristics and examine the contribution of biologically derived surface-active agents (biosurfactants) to the disruption or inhibition of microbial biofilms.

  14. PRODUCTION OPTIMIZATION USING AGENT-BASED SYSTEM

    Directory of Open Access Journals (Sweden)

    Aleksandar Vujovic

    2016-03-01

    Full Text Available Production systems suffer frequent changes due to the growing demand and need for providing market competitiveness. Therefore, the application of intelligent systems can greatly increase the level of flexibility and efficiency, but also reduce the overall costs. On example of system for the production of irregular and variable shaped parts by cutting the wooden flat surfaces, it is discussed the possibility of applying intelligent agent-based system. In order to implement it in the production process, it was necessary to firstly performed an analysis and assessment of the initial situation. Then, we spotted a weak points and gave some suggestions to improve process by application of agents. The obtained solution has reduced the number of engaged workers, reduced the scope of their duties, made faster flow of materials, improved its utilization and we finally introduced the scheme of the new agent-based manufacturing process that achieves the foregoing benefits.

  15. Enriching project organizations with formal change agents

    DEFF Research Database (Denmark)

    Eskerod, Pernille; Justesen, Just Bendix; Sjøgaard, Gisela

    2017-01-01

    and middle and top management support are major determinants of success within change projects. To select change agents that the employees respect and can identify with, combined with top management prioritization, is important in order for the project organization to benefit from the additional role...... change agents. Design/methodology/approach: The paper is based on a literature review and a multiple-case study in which six organizations participated in an action-oriented research project. The aim for the organizations was to obtain a better health status among the employees by accomplishing....... Practical implications: Selecting the “wrong” change agents can jeopardize a change project, even when the project is supported by top management and the target group members at the starting point are highly motivated to change. Originality/value: The research contributes to the understanding of project...

  16. DNA Topoisomerases as Targets for Antibacterial Agents.

    Science.gov (United States)

    Hiasa, Hiroshi

    2018-01-01

    DNA topoisomerases are proven therapeutic targets of antibacterial agents. Quinolones, especially fluoroquinolones, are the most successful topoisomerase-targeting antibacterial drugs. These drugs target type IIA topoisomerases in bacteria. Recent structural and biochemical studies on fluoroquinolones have provided the molecular basis for both their mechanism of action, as well as the molecular basis of bacterial resistance. Due to the development of drug resistance, including fluoroquinolone resistance, among bacterial pathogens, there is an urgent need to discover novel antibacterial agents. Recent advances in topoisomerase inhibitors may lead to the development of novel antibacterial drugs that are effective against fluoroquinolone-resistant pathogens. They include type IIA topoisomerase inhibitors that either interact with the GyrB/ParE subunit or form nick-containing ternary complexes. In addition, several topoisomerase I inhibitors have recently been identified. Thus, DNA topoisomerases remain important targets of antibacterial agents.

  17. Chromosome analyses of nurses handling cytostatic agents

    International Nuclear Information System (INIS)

    Waksvik, H.; Klepp, O.; Brogger, A.

    1981-01-01

    A cytogenetic study of ten nurses handling cytostatic agents (average exposure, 2150 hours) and ten female hospital clerks revealed an increased frequency of chromosome gaps and a slight increase in sister chromatid exchange frequency among the nurses. The increase may be due to exposure to cytostatic drugs and points to these agents as a possible occupational health hazard. A second group of 11 nurses handling cytostatic agents for a shorter period of time (average exposure, 1078 hours), and three other groups (eight nurses engaged in therapeutic and diagnostic radiology, nine nurses engaged in anesthesiology, and seven nurses in postoperative ward) did not differ from the office personnel, except for an increased frequency of chromosome gaps in the radiology group

  18. Glutamic acid as anticancer agent: An overview.

    Science.gov (United States)

    Dutta, Satyajit; Ray, Supratim; Nagarajan, K

    2013-10-01

    The objective of the article is to highlight various roles of glutamic acid like endogenic anticancer agent, conjugates to anticancer agents, and derivatives of glutamic acid as possible anticancer agents. Besides these emphases are given especially for two endogenous derivatives of glutamic acid such as glutamine and glutamate. Glutamine is a derivative of glutamic acid and is formed in the body from glutamic acid and ammonia in an energy requiring reaction catalyzed by glutamine synthase. It also possesses anticancer activity. So the transportation and metabolism of glutamine are also discussed for better understanding the role of glutamic acid. Glutamates are the carboxylate anions and salts of glutamic acid. Here the roles of various enzymes required for the metabolism of glutamates are also discussed.

  19. FIPA agent based network distributed control system

    Energy Technology Data Exchange (ETDEWEB)

    D. Abbott; V. Gyurjyan; G. Heyes; E. Jastrzembski; C. Timmer; E. Wolin

    2003-03-01

    A control system with the capabilities to combine heterogeneous control systems or processes into a uniform homogeneous environment is discussed. This dynamically extensible system is an example of the software system at the agent level of abstraction. This level of abstraction considers agents as atomic entities that communicate to implement the functionality of the control system. Agents' engineering aspects are addressed by adopting the domain independent software standard, formulated by FIPA. Jade core Java classes are used as a FIPA specification implementation. A special, lightweight, XML RDFS based, control oriented, ontology markup language is developed to standardize the description of the arbitrary control system data processor. Control processes, described in this language, are integrated into the global system at runtime, without actual programming. Fault tolerance and recovery issues are also addressed.

  20. [Antithyroid agents related agranulocytosis: Literature review].

    Science.gov (United States)

    Andrès, E; Weitten, T; Mourot-Cottet, R; Keller, O; Zulfiqar, A-A; Serraj, K; Vogel, T; Tebacher, M

    2016-08-01

    The antithyroid agents (carbimazole, methimazole, thiamazole, propylthiouracil and benzylthiouracile) are the drug class that is associated with a high risk of agranulocytosis. Acute and profound (<0.5×10(9)/L) isolated neutropenia occurring in a subject treated with antithyroid agents should be considered as a drug-induced agranulocytosis, until proven otherwise. The clinical spectrum ranges from discovery of acute severe but asymptomatic neutropenia, to isolated fever, localized infections (especially ear, nose and throat, or pulmonary) or septicemia. With an optimal management (discontinuation of antithyroid agents, antibiotics in the presence of fever or a documented infection, or use of hematopoietic growth factor) the current mortality is close to 2%. Copyright © 2016 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  1. Autonomous Formations of Multi-Agent Systems

    Science.gov (United States)

    Dhali, Sanjana; Joshi, Suresh M.

    2013-01-01

    Autonomous formation control of multi-agent dynamic systems has a number of applications that include ground-based and aerial robots and satellite formations. For air vehicles, formation flight ("flocking") has the potential to significantly increase airspace utilization as well as fuel efficiency. This presentation addresses two main problems in multi-agent formations: optimal role assignment to minimize the total cost (e.g., combined distance traveled by all agents); and maintaining formation geometry during flock motion. The Kuhn-Munkres ("Hungarian") algorithm is used for optimal assignment, and consensus-based leader-follower type control architecture is used to maintain formation shape despite the leader s independent movements. The methods are demonstrated by animated simulations.

  2. Physical Agents for Soft Tissue Injury.

    Science.gov (United States)

    2016-07-01

    The clinical management of soft tissue injuries of the lower limb commonly includes physical agents such as electrotherapy or ultrasound. However, the evidence about the effectiveness of physical agents varies, and their use remains controversial. A systematic review of randomized clinical trials (RCTs), published in the July 2016 issue of JOSPT, examined the benefits and safety risks of various physical agents for soft tissue injuries of the lower limb. Importantly, the review looked closely at the quality of the RCTs and focused on studies with low risk of bias. In this Perspectives for Practice, the authors explain the impact of their findings for clinicians treating patients with such musculoskeletal conditions. J Orthop Sports Phys Ther 2016;46(7):555. doi:10.2519/jospt.2016.0503.

  3. ECONOMÍA COMPUTACIONAL BASADA EN AGENTES

    Directory of Open Access Journals (Sweden)

    FABIÁN ANDRÉS GIRALDO GIRALDO

    2012-12-01

    Full Text Available El artículo tiene como objetivo mostrarvarios trabajos de investigación sobre un enfoque desimulación denominado Economía computacional basadaen agentes, el cual rechaza las asunciones delos enfoques de estudio tradicionales que indican quela economía es un sistema cerrado que eventualmentelogra un estado de equilibrio, en el que deben realizarsesupuestos de racionalidad perfecta e inversioneshomogéneas para que los modelos sean tratadosanalíticamente. En su lugar, ve a la economía comoun sistema complejo, adaptativo y dinámico. Estenuevo enfoque permite usar la simulación basada enagentes para comprender que varios agentes económicos(firmas, grupos económicos con sus propiasreglas y objetivos, son capaces de interactuar entresí y con su entorno para obtener comportamientosemergentes que no son explicables directamente delas propiedades de los agentes individuales.

  4. Animated Pedagogical Agents: A Review of Agent Technology Software in Electronic Learning Environments

    Science.gov (United States)

    Govindasamy, Malliga K.

    2014-01-01

    Agent technology has become one of the dynamic and most interesting areas of computer science in recent years. The dynamism of this technology has resulted in computer generated characters, known as pedagogical agent, entering the digital learning environments in increasing numbers. Commonly deployed in implementing tutoring strategies, these…

  5. A Comparison of Organization-Centered and Agent-Centered Multi-Agent Systems

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Villadsen, Jørgen

    2013-01-01

    Whereas most classical multi-agent systems have the agent in center, there has recently been a development towards focusing more on the organization of the system, thereby allowing the designer to focus on what the system goals are, without considering how the goals should be fulfilled. We have d...

  6. Nondestructive Intervention to Multi-Agent Systems through an Intelligent Agent

    Science.gov (United States)

    Han, Jing; Wang, Lin

    2013-01-01

    For a given multi-agent system where the local interaction rule of the existing agents can not be re-designed, one way to intervene the collective behavior of the system is to add one or a few special agents into the group which are still treated as normal agents by the existing ones. We study how to lead a Vicsek-like flocking model to reach synchronization by adding special agents. A popular method is to add some simple leaders (fixed-headings agents). However, we add one intelligent agent, called ‘shill’, which uses online feedback information of the group to decide the shill's moving direction at each step. A novel strategy for the shill to coordinate the group is proposed. It is strictly proved that a shill with this strategy and a limited speed can synchronize every agent in the group. The computer simulations show the effectiveness of this strategy in different scenarios, including different group sizes, shill speed, and with or without noise. Compared to the method of adding some fixed-heading leaders, our method can guarantee synchronization for any initial configuration in the deterministic scenario and improve the synchronization level significantly in low density groups, or model with noise. This suggests the advantage and power of feedback information in intervention of collective behavior. PMID:23658695

  7. Nondestructive intervention to multi-agent systems through an intelligent agent.

    Directory of Open Access Journals (Sweden)

    Jing Han

    Full Text Available For a given multi-agent system where the local interaction rule of the existing agents can not be re-designed, one way to intervene the collective behavior of the system is to add one or a few special agents into the group which are still treated as normal agents by the existing ones. We study how to lead a Vicsek-like flocking model to reach synchronization by adding special agents. A popular method is to add some simple leaders (fixed-headings agents. However, we add one intelligent agent, called 'shill', which uses online feedback information of the group to decide the shill's moving direction at each step. A novel strategy for the shill to coordinate the group is proposed. It is strictly proved that a shill with this strategy and a limited speed can synchronize every agent in the group. The computer simulations show the effectiveness of this strategy in different scenarios, including different group sizes, shill speed, and with or without noise. Compared to the method of adding some fixed-heading leaders, our method can guarantee synchronization for any initial configuration in the deterministic scenario and improve the synchronization level significantly in low density groups, or model with noise. This suggests the advantage and power of feedback information in intervention of collective behavior.

  8. Quitina y carboximetilquitosana como agentes desintegrantes

    OpenAIRE

    Sol A Fernández Monagas; María D Rodríguez Albadalejo; Ofelia Bilbao Revoredo; Olga M Nieto Acosta

    1998-01-01

    Se realizó un estudio comparativo de la quitina y la carboximetilquitosana como agentes desintegrantes, y se evaluó la influencia ejercida por el método empleado en la elaboración de las tabletas sobre la actividad desintegrante de ambos polímeros. La quitina presentó buenas características como agente desintegrante independientemente del método utilizado en la elaboración de las tabletas, mientras que la actividad desintegrante de la carboximetilquitosana fue afectada por el proceso de granu...

  9. Psoriatic arthritis: treatment strategies using biologic agents

    Directory of Open Access Journals (Sweden)

    C. Palazzi

    2012-06-01

    Full Text Available The traditional management of psoriatic arthritis (PsA includes NSAIDs, corticosteroids and DMARDs. Advancement in the knowledge of the immunopathogenesis of PsA has been associated with the development of biologic agents which have revolutionized the management of the disease. Among biologics drugs, there are the 4 currently availablee anti-TNFα blocking agents (etanercept, infliximab, adalimumab and golimumab which are more effective than traditional DMARDs on symptoms/signs of inflammation, quality of life, function, and in inhibiting the progression of the structural joint damage. Despite of the high cost, TNF inhibitors are costeffective on both the musculoskeletal and skin manifestations of psoriatic disease.

  10. Broad-Spectrum Drugs Against Viral Agents

    Directory of Open Access Journals (Sweden)

    Jonathan P. Wong

    2008-09-01

    Full Text Available Development of antivirals has focused primarily on vaccines and on treatments for specific viral agents. Although effective, these approaches may be limited in situations where the etiologic agent is unknown or when the target virus has undergone mutation, recombination or reassortment. Augmentation of the innate immune response may be an effective alternative for disease amelioration. Nonspecific, broad-spectrum immune responses can be induced by double-stranded (dsRNAs such as poly (ICLC, or oligonucleotides (ODNs containing unmethylated deocycytidyl-deoxyguanosinyl (CpG motifs. These may offer protection against various bacterial and viral pathogens regardless of their genetic makeup, zoonotic origin or drug resistance.

  11. Synthesis of isotopically labeled threat agents

    International Nuclear Information System (INIS)

    Ott, D.G.; Reisfeld, M.J.; Whaley, T.W.

    1986-01-01

    The blister agents, bis(2-chloroethyl) sulfide (HD or sulfur mustard) and dichloro(2-chlorovinyl)arsine (L or Lewisite) were prepared with carbon-14 at all carbon atoms. The synthesis of HD proceeded from 2-bromoethanol. In the Lewisite synthesis, chloro(2-chlorovinyl)mercury, from acetylene, was converted to L, along with the bis- and tris-(chlorovinyl) compounds, which were separated by thin layer chromatography. The nerve agents, isopropyl methylphosphonofluoridate (GB or sarin) and pinacolyl methylphosphonofluoridate (GD or soman) were labeled in the methyl group attached to phosphorus with either deuterium, tritium, or carbon-14 starting from the labeled iodomethane. 4 refs

  12. Organophosphate Nerve Agent Detection with Europium Complexes

    Directory of Open Access Journals (Sweden)

    Jake R. Schwierking

    2004-01-01

    Full Text Available We explore the detection of paraoxon, a model compound for nonvolatile organophosphate nerve agents such as VX. The detection utilizes europium complexes with 1,10 phenanthroline and thenoyltrifluoroacetone as sensitizing ligands. Both europium luminescence quenching and luminescence enhancement modalities are involved in the detection, which is simple, rapid, and sensitive. It is adaptable as well to the more volatile fluorophosphate nerve agents. It involves nothing more than visual luminescence observation under sample illumination by an ordinary hand-held ultraviolet lamp.

  13. New agents: great expectations not realized.

    Science.gov (United States)

    Lancet, Jeffrey E

    2013-09-01

    A number of new agents in acute myeloid leukemia (AML) have held much promise in recent years, but most have failed to change the therapeutic landscape. Indeed, with the exception of gemtuzumab ozogamicin (which was subsequently voluntarily withdrawn from the commercial market), no new agent has been approved for acute myeloid leukemia (AML) beyond the 7 + 3 regimen, which was has been in use for over 40 years. This review touches upon the potential reasons for these failures and explores the newer therapeutic approaches being pursued in AML. Copyright © 2013. Published by Elsevier Ltd.

  14. Chelating agents in pharmacology, toxicology and therapeutics

    International Nuclear Information System (INIS)

    1988-01-01

    The proceedings contain 71 abstracts of papers. Fourteen abstracts were inputted in INIS. The topics covered include: the effects of chelating agents on the retention of 63 Ni, 109 Cd, 203 Hg, 144 Ce, 95 Nb and the excretion of 210 Po, 63 Ni, 48 V, 239 Pu, 241 Am, 54 Mn; the applications of tracer techniques for studies of the efficacy of chelation therapy in patients with heart and brain disorders; and the treatment of metal poisoning with chelating agents. (J.P.)

  15. A Diversified Investment Strategy Using Autonomous Agents

    Science.gov (United States)

    Barbosa, Rui Pedro; Belo, Orlando

    In a previously published article, we presented an architecture for implementing agents with the ability to trade autonomously in the Forex market. At the core of this architecture is an ensemble of classification and regression models that is used to predict the direction of the price of a currency pair. In this paper, we will describe a diversified investment strategy consisting of five agents which were implemented using that architecture. By simulating trades with 18 months of out-of-sample data, we will demonstrate that data mining models can produce profitable predictions, and that the trading risk can be diminished through investment diversification.

  16. Novel anti-inflammatory agents in COPD

    DEFF Research Database (Denmark)

    Loukides, Stelios; Bartziokas, Konstantinos; Vestbo, Jørgen

    2013-01-01

    Inflammation plays a central role in chronic obstructive pulmonary disease (COPD). COPD related inflammation is less responsive to inhaled steroids compared to asthma. There are three major novel anti-inflammatory approaches to the management of COPD. The first approach is phosphodiesterase...... on these strategies exist at the moment. A third potential approach involves novel agents whose mechanism of action is closely related to COPD mechanisms and pathophysiology. Such novel treatments are of great interest since they may treat both COPD and co-morbidities. Several novel agents are currently under...

  17. Agentes Comunitários de Saúde e os sentidos de "ser agente" Community Health Agents and the meanings of "being an agent"

    Directory of Open Access Journals (Sweden)

    Viviane Milan Pupin

    2008-08-01

    Full Text Available O Programa Saúde da Família constitui-se enquanto estratégia de mudança do modelo assistencial. O artigo apresenta os resultados de uma pesquisa qualitativa sobre os sentidos de "ser agente" produzidos, por meio de entrevistas abertas, com Agentes Comunitários de Saúde que trabalham nos cinco Núcleos de Saúde da Família da cidade de Ribeirão Preto - São Paulo, vinculados à Faculdade de Medicina de Ribeirão Preto - USP. As entrevistas foram gravadas e transcritas na íntegra e analisadas segundo princípios da análise de conteúdo. A análise permitiu a descrição de sentidos acerca de ser agente subdivididos em: Sentidos produzidos na relação com a comunidade e Sentidos produzidos na relação com a equipe. A análise dos sentidos de ser agente possibilitou construir um diálogo sobre as tensões relacionadas a um fazer em saúde ora permeado por concepções atreladas ao modelo biomédico, ora atrelado aos novos paradigmas em saúde.The Family Health Program consists of a strategy to change the health care model. This article presents the results from a qualitative study about the meanings of "being an agent" obtained through open interviews with Community Health Agents who work in five Family Health Centers of the Ribeirão Preto School of Medicine (University of São Paulo, located in Ribeirão Preto, São Paulo. Interviews were tape recorded, fully transcribed, and then content analyzed. The analysis allowed for descriptions of meanings toward "being an agent", subdivided into: Meanings produced by relationships with the community, and Meanings produced by relationships with the team. Analyzing the meanings of being an agent provided the establishment of a dialogue about the tensions related to a health practice that is at times influenced by conceptions associated with the biomedical method, and at other times with the new health paradigm.

  18. A fiber optic sensor for nerve agent

    Science.gov (United States)

    Cordero, Steven R.; Mukamal, Harold; Low, Aaron; Locke, Edward P.; Lieberman, Robert A.

    2006-10-01

    We report advances made on the development of a fiber optic nerve agent sensor having its entire length as the sensing element. The optical fiber is multimode, and consists of a fused-silica core and a nerve agent sensitive cladding. Upon exposure to sarin gas, the cladding changes color, resulting in an alteration of the light intensity throughput. The fiber is mass produced using a conventional fiber optic draw tower. This technology could replace, or be used with, a collection of point-detectors to protect personnel, buildings and perimeters from dangerous chemical attacks.

  19. Developing Agent-Oriented Video Surveillance System through Agent-Oriented Methodology (AOM

    Directory of Open Access Journals (Sweden)

    Cheah Wai Shiang

    2016-12-01

    Full Text Available Agent-oriented methodology (AOM is a comprehensive and unified agent methodology for agent-oriented software development. Although AOM is claimed to be able to cope with a complex system development, it is still not yet determined up to what extent this may be true. Therefore, it is vital to conduct an investigation to validate this methodology. This paper presents the adoption of AOM in developing an agent-oriented video surveillance system (VSS. An intruder handling scenario is designed and implemented through AOM. AOM provides an alternative method to engineer a distributed security system in a systematic manner. It presents the security system at a holistic view; provides a better conceptualization of agent-oriented security system and supports rapid prototyping as well as simulation of video surveillance system.

  20. 10th KES Conference on Agent and Multi-Agent Systems : Technologies and Applications

    CERN Document Server

    Chen-Burger, Yun-Heh; Howlett, Robert; Jain, Lakhmi

    2016-01-01

    The modern economy is driven by technologies and knowledge. Digital technologies can free, shift and multiply choices, often intruding on the space of other industries, by providing new ways of conducting business operations and creating values for customers and companies. The topics covered in this volume include software agents, multi-agent systems, agent modelling, mobile and cloud computing, big data analysis, business intelligence, artificial intelligence, social systems, computer embedded systems and nature inspired manufacturing, etc. that contribute to the modern Digital Economy. This volume highlights new trends and challenges in agent, new digital and knowledge economy research and includes 28 papers classified in the following specific topics: business process management, agent-based modeling and simulation, anthropic-oriented computing, learning paradigms, business informatics and gaming, digital economy, and advances in networked virtual enterprises. Published papers were selected for presentatio...

  1. Multi-agent Cooperation in a Planning Framework

    NARCIS (Netherlands)

    De Weerdt, M.M.; Bos, A.; Tonino, J.F.M.; Witteveen, C.

    2000-01-01

    The promise of multi-agent systems is that multiple agents can solve problems more efficiently than single agents can. In this paper we propose a method to implement cooperation between agents in the planning phase, in order to achive more cost-effective solutions than without cooperation. Two

  2. A dialogue agent for navigation support in virtual reality

    NARCIS (Netherlands)

    Jacko, J.; van Luin, J.; op den Akker, Hendrikus J.A.; Sears, A.; Nijholt, Antinus

    We describe our work on designing a natural language accessible navigation agent for a virtual reality (VR) environment. The agent is part of an agent framework, which means that it can communicate with other agents. Its navigation task consists of guiding the visitors in the environment and to

  3. Relaxing Synchronization in Parallel Agent-Based Road Traffic Simulation

    NARCIS (Netherlands)

    Xu, Y.; Cai, W.; Aydt, H.; Lees, M.; Zehe, D.

    Large-scale agent-based traffic simulation is computationally intensive. Parallel computing can help to speed up agent-based traffic simulation. Parallelization of agent-based traffic simulations is generally achieved by decomposing the road network into subregions. The agents in each subregion are

  4. Schools as Agents of Social Exclusion and Inclusion

    Science.gov (United States)

    Razer, Michal; Friedman, Victor J.; Warshofsky, Boaz

    2013-01-01

    Although schools are usually regarded as important agents for social inclusion, research has shown that they may also function as agents of exclusion itself. The goal of this paper is to deepen our understanding of how schools function as agents of exclusion and how they can become more effective agents of inclusion. It is based on action research…

  5. 49 CFR 375.205 - May I have agents?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false May I have agents? 375.205 Section 375.205... General Responsibilities § 375.205 May I have agents? (a) You may have agents provided you comply with... performs such services only on an emergency or temporary basis. (b) If you have agents, you must have...

  6. Quitina y carboximetilquitosana como agentes desintegrantes

    Directory of Open Access Journals (Sweden)

    Sol A Fernández Monagas

    1998-08-01

    Full Text Available Se realizó un estudio comparativo de la quitina y la carboximetilquitosana como agentes desintegrantes, y se evaluó la influencia ejercida por el método empleado en la elaboración de las tabletas sobre la actividad desintegrante de ambos polímeros. La quitina presentó buenas características como agente desintegrante independientemente del método utilizado en la elaboración de las tabletas, mientras que la actividad desintegrante de la carboximetilquitosana fue afectada por el proceso de granulación.A comparative study of chitin and carboxymethylchitosan as disintegrating agents was wade made. The influence exerted bu tje method used in the preparation of the tablets on the disintegrating activity of both polymers was evaluated. Chitin proved to have good characteristics as a disintegrating agent independently of the method used to make tablets. The disintegrating activity of carboxymethylchitosan was affected by the granulation process.

  7. Raising agents: sources of human social intelligence

    NARCIS (Netherlands)

    Hofstede, G.J.

    2014-01-01

    This paper urges that if we wish to give social intelligence to our agents, it pays to look at how we acquired our social intelligence ourselves. Our drives and motives are innate and deeply social. Next, as children we are social-ized to acquire norms and values. This motivational and group-based

  8. GRASP agents: social first, intelligent later

    NARCIS (Netherlands)

    Hofstede, G.J.

    2017-01-01

    This paper urges that if we wish to give social intelligence to our agents, it pays to look at how we acquired our social intelligence ourselves. We are born with drives and motives that are innate and deeply social. Next, as children we are socialized to acquire norms and values and to understand

  9. Immediate Hypersensitivity Reaction to Chemotherapeutic Agents.

    Science.gov (United States)

    Giavina-Bianchi, Pedro; Patil, Sarita U; Banerji, Aleena

    An increase by 70% in new cases of cancer is expected over the next 2 decades, with more than 8 million people dying each year from the disease, an estimated 13% of all deaths worldwide. Several new chemotherapeutic agents have been rapidly developed and many of them approved through a fast-track process. In parallel, adverse reactions to chemotherapy have increased dramatically worldwide, frequently preventing the use of first-line therapy for cancer and jeopardizing patients' treatment outcomes. The present review focuses on immediate hypersensitivity reactions (IHRs) induced by chemotherapeutic agents. We address general features of these reactions and specific characteristics of the most prevalent agents involved. On the basis of scientific evidence, we suggest classifying acute reactions to chemotherapy as toxic, systemic inflammatory response syndrome, and IHRs (anaphylactic-type reactions). IHRs to chemotherapeutic agents are unpredictable adverse reactions with potentially lethal consequences. Correct diagnosis and proper management of oncologic patients with IHRs are fundamental in order not to deprive them of the first-line treatment for their disease. In this scenario, rapid drug desensitization is a groundbreaking procedure that enables selected patients to receive the drug that induced an IHR in a safe way, minimizing the risks of anaphylaxis and treatment failure. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  10. Implementation of Ontology Mapping for Computational Agents

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman

    2006-01-01

    Roč. 1, č. 1 (2006), s. 58-63 ISSN 1991-8755 R&D Projects: GA AV ČR 1ET100300419 Institutional research plan: CEZ:AV0Z10300504 Keywords : multi-agent systems * ontology * computational intelligence Subject RIV: IN - Informatics, Computer Science

  11. newspapers' agricultural agenda setting and extension agents ...

    African Journals Online (AJOL)

    p2333147

    issue 'agendas' there is need, as asserted by McQuail (1987:75) for a combination of content analysis showing media attention to different issues in the relevant period and some indication of relevant media used by the public concerned, in this study, the extension agents. Agenda-setting according to Davis and Robinson ...

  12. The Hybrid Ethical Reasoning Agent IMMANUEL

    DEFF Research Database (Denmark)

    Bentzen, Martin Mose; Linder, Felix

    We introduce a novel software library that supportsthe implementation of hybrid ethical reasoning agents (HERA).The objective is to make moral principles available to robotprogramming. At its current stage, HERA can assess the moralpermissibility of actions using the principle of double effect...

  13. Supporting a Learner Community with Software Agents

    Science.gov (United States)

    Taurisson, Neil; Tchounikine, Pierre

    2004-01-01

    This paper describes a multi-agent approach that aims at supporting learners involved in a collective activity. We consider pedagogical situations where students have to explicitly define the articulation of their collective work and then achieve the different tasks they have defined. Our objective is to support these students by taking some of…

  14. Pharmacological stress agents in nuclear cardiology

    International Nuclear Information System (INIS)

    Buscombe, J.R.

    2004-01-01

    Treadmill test combined with myocardial perfusion scintigraphy (MPS) is a commonly used technique in the assessment of coronary artery disease. However there are a group of patients who may not be able to undergo treadmill tests. Patients with underlying conditions like neuromuscular disease, musculoskeletal disorder, heart failure and end-stage renal disease (ESRD) on renal dialysis would find it difficult to perform exercise on a treadmill or bicycle ergometer. These conditions prevent them from performing adequate exercise. Such patients would benefit from pharmacological stress procedures combined with MPS. Nuclear medicine departments use various pharmacological agents while performing stress tests on cardiac patients. The most commonly used pharmacological agents for cardiac stress are coronary vasodilators and catecholamines. In addition to these agents, adjuvant use of nitrates and atropine is also a common practice in nuclear cardiology. This review addresses various physiological and pharmacological properties of the commonly used pharmacological stress agents in MPS and critically analyses their advantages and disadvantages, as well as their safety and efficacy. (author)

  15. Glutamate esters as agents for cholescintigraphy

    International Nuclear Information System (INIS)

    Colombetti, L.

    1976-01-01

    Several sup(99m)Tc-labelled aldehyde glutamate complexes having similar pharmacological properties as sup(99m)Tc-pyridoxylidene glutamate have been prepared. The dynamic behaviour of these compounds in dogs and rabbits was studied using a digital computer and scintillation camera. The aldehyde-glutamate complex promises to be a useful agent for the dynamic study of hepatic and biliary function

  16. Self-explaining agents in virtual training

    NARCIS (Netherlands)

    Harbers, M.; Bosch, K. van den; Meyer, J.J.C.

    2008-01-01

    Virtual training systems are increasingly used for the training of complex, dynamic tasks. To give trainees the opportunity to train autonomously, intelligent agents are used to generate the behavior of the virtual players in the training scenario. For effective training however, trainees should be

  17. Learning in engineered multi-agent systems

    Science.gov (United States)

    Menon, Anup

    Consider the problem of maximizing the total power produced by a wind farm. Due to aerodynamic interactions between wind turbines, each turbine maximizing its individual power---as is the case in present-day wind farms---does not lead to optimal farm-level power capture. Further, there are no good models to capture the said aerodynamic interactions, rendering model based optimization techniques ineffective. Thus, model-free distributed algorithms are needed that help turbines adapt their power production on-line so as to maximize farm-level power capture. Motivated by such problems, the main focus of this dissertation is a distributed model-free optimization problem in the context of multi-agent systems. The set-up comprises of a fixed number of agents, each of which can pick an action and observe the value of its individual utility function. An individual's utility function may depend on the collective action taken by all agents. The exact functional form (or model) of the agent utility functions, however, are unknown; an agent can only measure the numeric value of its utility. The objective of the multi-agent system is to optimize the welfare function (i.e. sum of the individual utility functions). Such a collaborative task requires communications between agents and we allow for the possibility of such inter-agent communications. We also pay attention to the role played by the pattern of such information exchange on certain aspects of performance. We develop two algorithms to solve this problem. The first one, engineered Interactive Trial and Error Learning (eITEL) algorithm, is based on a line of work in the Learning in Games literature and applies when agent actions are drawn from finite sets. While in a model-free setting, we introduce a novel qualitative graph-theoretic framework to encode known directed interactions of the form "which agents' action affect which others' payoff" (interaction graph). We encode explicit inter-agent communications in a directed

  18. Trusted intermediating agents in electronic trade networks

    NARCIS (Netherlands)

    T.B. Klos (Tomas); F. Alkemade (Floortje)

    2005-01-01

    htmlabstract Electronic commerce and trading of information goods significantly impact the role of intermediaries: consumers can bypass intermediating agents by forming direct links to producers. One reason that traditional intermediaries can still make a profit, is that they have more knowledge of

  19. Beyond Needs Assessments: Marketing as Change Agent.

    Science.gov (United States)

    Piland, William E.

    1984-01-01

    Views marketing techniques as agents of change providing valuable assistance to community college decision makers. Discusses the importance of a balance among the four P's of marketing (i.e., promotion, price, place, and product); and seven procedural steps in developing a sound marketing strategy. (DMM)

  20. Adaptive hierarchical multi-agent organizations

    NARCIS (Netherlands)

    Ghijsen, M.; Jansweijer, W.N.H.; Wielinga, B.J.; Babuška, R.; Groen, F.C.A.

    2010-01-01

    In this chapter, we discuss the design of adaptive hierarchical organizations for multi-agent systems (MAS). Hierarchical organizations have a number of advantages such as their ability to handle complex problems and their scalability to large organizations. By introducing adaptivity in the