Magnetic Exchange Couplings with Range-Separated Hybrid Density Functionals.
Peralta, Juan E; Melo, Juan I
2010-06-08
We investigate the effect of Hartree-Fock range-separation on the calculation of magnetic exchange couplings in a set of nine bimetallic transition-metal complexes containing 3d elements (V, Cr, Mn, and Cu). To this end, we have compared magnetic exchange couplings calculated as self-consistent energy differences using two global hybrid functionals, B3LYP (Becke 3-parameter exchange and Lee-Yang-Parr correlation) and PBEh (hybrid Perdew-Burke-Ernzerhof) with the short-range separated HSE (Heyd-Scuseria-Ernzerhof) and the long-range corrected LC-ωPBE. Our results show that, although there is no clear superiority of any of these functionals when compared with experimental data, the LC-ωPBE provides a better description of the magnetization on the metallic centers, yielding self-consistent solutions that mimic more closely a Heisenberg-like behavior.
LuChunHai; Liao Jun Sheng; Sun Ying; WangXiaoLin
2002-01-01
The density functional theory method using B3' exchange and Lee-Yang-Parr's correlation function (B3LYP) with 6-31G** basis set were used to study and optimize equilibrium structure and fundamental vibrational frequencies in the equilibrium for CH4, CH3D, CH2D2, CHD3 and CD4. The relative result error from 1.1% to 6.3% were obtained between the calculation and the observation values of fundamental vibrational frequencies. After scaled, the relative result error is between 0.1% and - 2.9%. This method is used to study period properties of methane that some hydrogen atoms are replaced by tritium atoms. Following deuterium or tritium atom number rising in methane, entropy increases, but zero-point vibrational energy, heat capacity and enthalpy reduces
A second-order unconstrained optimization method for canonical-ensemble density-functional methods
Nygaard, Cecilie R.; Olsen, Jeppe
2013-03-01
A second order converging method of ensemble optimization (SOEO) in the framework of Kohn-Sham Density-Functional Theory is presented, where the energy is minimized with respect to an ensemble density matrix. It is general in the sense that the number of fractionally occupied orbitals is not predefined, but rather it is optimized by the algorithm. SOEO is a second order Newton-Raphson method of optimization, where both the form of the orbitals and the occupation numbers are optimized simultaneously. To keep the occupation numbers between zero and two, a set of occupation angles is defined, from which the occupation numbers are expressed as trigonometric functions. The total number of electrons is controlled by a built-in second order restriction of the Newton-Raphson equations, which can be deactivated in the case of a grand-canonical ensemble (where the total number of electrons is allowed to change). To test the optimization method, dissociation curves for diatomic carbon are produced using different functionals for the exchange-correlation energy. These curves show that SOEO favors symmetry broken pure-state solutions when using functionals with exact exchange such as Hartree-Fock and Becke three-parameter Lee-Yang-Parr. This is explained by an unphysical contribution to the exact exchange energy from interactions between fractional occupations. For functionals without exact exchange, such as local density approximation or Becke Lee-Yang-Parr, ensemble solutions are favored at interatomic distances larger than the equilibrium distance. Calculations on the chromium dimer are also discussed. They show that SOEO is able to converge to ensemble solutions for systems that are more complicated than diatomic carbon.
Towards improved local hybrid functionals by calibration of exchange-energy densities
International Nuclear Information System (INIS)
Arbuznikov, Alexei V.; Kaupp, Martin
2014-01-01
A new approach for the calibration of (semi-)local and exact exchange-energy densities in the context of local hybrid functionals is reported. The calibration functions are derived from only the electron density and its spatial derivatives, avoiding spatial derivatives of the exact-exchange energy density or other computationally unfavorable contributions. The calibration functions fulfill the seven more important out of nine known exact constraints. It is shown that calibration improves substantially the definition of a non-dynamical correlation energy term for generalized gradient approximation (GGA)-based local hybrids. Moreover, gauge artifacts in the potential-energy curves of noble-gas dimers may be corrected by calibration. The developed calibration functions are then evaluated for a large range of energy-related properties (atomization energies, reaction barriers, ionization potentials, electron affinities, and total atomic energies) of three sets of local hybrids, using a simple one-parameter local-mixing. The functionals are based on (a) local spin-density approximation (LSDA) or (b) Perdew-Burke-Ernzerhof (PBE) exchange and correlation, and on (c) Becke-88 (B88) exchange and Lee-Yang-Parr (LYP) correlation. While the uncalibrated GGA-based functionals usually provide very poor thermochemical data, calibration allows a dramatic improvement, accompanied by only a small deterioration of reaction barriers. In particular, an optimized BLYP-based local-hybrid functional has been found that is a substantial improvement over the underlying global hybrids, as well as over previously reported LSDA-based local hybrids. It is expected that the present calibration approach will pave the way towards new generations of more accurate hyper-GGA functionals based on a local mixing of exchange-energy densities
Khanniche, Sarah; Louis, Florent; Cantrel, Laurent; Černušák, Ivan
2016-03-17
To get an insight into the possible reactivity between iodine oxides and CO, a first step was to study the thermochemical properties and kinetic parameters of the reaction between IO and CO using theoretical chemistry tools. All stationary points involved were optimized using the Becke's three-parameter hybrid exchange functional coupled with the Lee-Yang-Parr nonlocal correlation functional (B3LYP) and the Møller-Plesset second-order perturbation theory (MP2). Single-point energy calculations were performed using the coupled cluster theory with the iterative inclusion of singles and doubles and the perturbative estimation for triple excitations (CCSD(T)) and the aug-cc-pVnZ (n = T, Q, and 5) basis sets on geometries previously optimized at the aug-cc-pVTZ level. The energetics was then recalculated using the one-component DK-CCSD(T) approach with the relativistic ANO basis sets. The spin-orbit coupling for the iodine containing species was calculated a posteriori using the restricted active space state interaction method in conjunction with the multiconfigurational perturbation theory (CASPT2/RASSI) employing the complete active space (CASSCF) wave function as the reference. The CCSD(T) energies were also corrected for BSSE for molecular complexes and refined with the extrapolation to CBS limit while the DK-CCSD(T) values were refined with the extrapolation to FCI. The exploration of the potential energy surface revealed a two-steps mechanism with a trans and a cis pathway. The rate constants for the direct and complex mechanism were computed as a function of temperature (250-2500 K) using the canonical transition state theory. The three-parameter Arrhenius expressions obtained for the direct and indirect mechanism at the DK-CCSD(T)-cf level of theory is 1.49 × 10(-17) × T(1.77) exp(-47.4 (kJ mol(-1))/RT).
Kishi, Ryohei; Bonness, Sean; Yoneda, Kyohei; Takahashi, Hideaki; Nakano, Masayoshi; Botek, Edith; Champagne, Benoît; Kubo, Takashi; Kamada, Kenji; Ohta, Koji; Tsuneda, Takao
2010-03-07
Within the spin-unrestricted density functional theory (DFT) the long-range correction (LC) scheme combined with the Becke-Lee-Yang-Parr exchange-correlation functional, referred to as LC-UBLYP method, has been applied to the calculation of the second hyperpolarizability (gamma) of open-shell singlet diradical systems of increasing complexity and has demonstrated good performance: (i) for the simplest H(2) dissociation model, the gamma values calculated by the LC-UBLYP method significantly overshoot the full configuration interaction result but reproduce qualitatively the evolution of gamma as a function of the diradical character, (ii) for small singlet diradical 1,3-dipole systems, the diradical character dependence of gamma determined by the UCCSD and UCCSD(T) reference methods is reproduced semiquantitatively by the LC-UBLYP method except in the small diradical character region, where the spin-unrestricted solutions coincide with spin-restricted solutions, (iii) the LC-UBLYP method also closely reproduces the UCCSD(T) results on the diradical character dependence of gamma of the p-quinodimethane model system, particularly in the intermediate and large diradical character regions, whereas it shows an abrupt change for a diradical character (y) close to 0.2 originating from the triplet instability, (iv) the reliability of LC-UBLYP to reproduce reference coupled cluster results on open-shell singlet systems with intermediate and large diradical characters has also been substantiated in the case of gamma of 1,4-bis-(imidazol-2-ylidene)-cyclohexa-2,5-diene (BI2Y), then (v), for real systems built from a pair of phenalenyl radicals separated by a conjugated linker, the LC-UBLYP results have been found to closely match the UBHandHLYP values-which, for small systems are in good agreement with those obtained using correlated molecular orbital methods-whereas the UB3LYP results can be much different. These results are not only important from the viewpoint of an efficient
International Nuclear Information System (INIS)
Stroppa, A; Kresse, G
2008-01-01
A study of the adsorption of CO on late 4d and 5d transition metal (111) surfaces (Ru, Rh, Pd, Ag, Os, Ir and Pt) considering atop and hollow site adsorption is presented. The applied functionals include the gradient-corrected Perdew-Burke-Ernzerhof (PBE) and Becke-Lee-Yang-Parr (BLYP) functionals, and the corresponding hybrid Hartree-Fock density functionals HSE and B3LYP. We find that PBE-based hybrid functionals (specifically HSE) yield, with the exception of Pt, the correct site order on all considered metals, but they also considerably overestimate the adsorption energies compared to experiment. On the other hand, the semi-local BLYP functional and the corresponding hybrid functional B3LYP yield very satisfactory adsorption energies and the correct adsorption site for all surfaces. We are thus faced with a Procrustean problem: the B3LYP and BLYP functionals seem to be the overall best choice for describing adsorption on metal surfaces, but they simultaneously fail to account well for the properties of the metal, vastly overestimating the equilibrium volume and underestimating the atomization energies. Setting out from these observations, general conclusions are drawn on the relative merits and drawbacks of various semi-local and hybrid functionals. The discussion includes a revised version of the PBE functional specifically optimized for bulk properties and surface energies (PBEsol), a revised version of the PBE functional specifically optimized to predict accurate adsorption energies (rPBE), as well as the aforementioned BLYP functional. We conclude that no semi-local functional is capable of describing all aspects properly, and including non-local exchange also only improves some but worsens other properties
Bouzid, Assil; Ori, Guido; Boero, Mauro; Lampin, Evelyne; Massobrio, Carlo
2017-12-01
The amorphous structure of the phase change material Ge2Sb2Te5 (GST) has been the object of controversial structural models. By employing first-principles molecular dynamics within density functional theory, we are able to obtain quantitative agreement with experimental structural findings for the topology of glassy GST. To this end, we take full advantage of a thoughtful, well established choice of the exchange-correlation (XC) functional (Becke-Lee-Yang-Parr, BLYP), combined with appropriate options for the nonlocal part in the pseudopotential construction for Ge. Results obtained by using the Perdew-Burke-Ernzerhof (PBE) XC functional and a similar strategy for the Ge pseudopotential constructions are also presented, since they are very valuable and worthy of consideration. The atomic structure of glassy GST is characterized by Ge atoms lying in a predominant tetrahedral network, albeit a non-negligible fraction of Ge atoms are also found in defective octahedra.
Pair Correlation Function Integrals
DEFF Research Database (Denmark)
Wedberg, Nils Hejle Rasmus Ingemar; O'Connell, John P.; Peters, Günther H.J.
2011-01-01
We describe a method for extending radial distribution functions obtained from molecular simulations of pure and mixed molecular fluids to arbitrary distances. The method allows total correlation function integrals to be reliably calculated from simulations of relatively small systems. The long-d...... distribution function has structure beyond the sampling limit imposed by the system size, the integration is more reliable, and usually more accurate, than simple integral truncation.......We describe a method for extending radial distribution functions obtained from molecular simulations of pure and mixed molecular fluids to arbitrary distances. The method allows total correlation function integrals to be reliably calculated from simulations of relatively small systems. The long......, and J. Abildskov, Mol. Simul. 36, 1243 (2010); Fluid Phase Equilib. 302, 32 (2011)], but describe here its theoretical basis more thoroughly and derive long-distance approximations for the direct correlation functions. We describe the numerical implementation of the method in detail, and report...
Confinement from correlation functions
Fister, Leonard; Pawlowski, Jan M.
2013-08-01
We compute the Polyakov loop potential in Yang-Mills theory from the fully dressed primitively divergent correlation functions only. This is done in a variety of functional approaches ranging from functional renormalization group equations over Dyson-Schwinger equations to two-particle irreducible functionals. We present a confinement criterion that links the infrared behavior of propagators and vertices to the Polyakov loop expectation value. The present work extends the works of [J. Braun , Phys. Lett. B 684, 262 (2010)PYLBAJ0370-2693; F. Marhauser and J. M. Pawlowski, arXiv:0812.1144; J. Braun , Eur. Phys. J. C 70, 689 (2010)EPCFFB1434-6044] to general functional methods and sharpens the confinement criterion presented there. The computations are based on the thermal correlation functions in the Landau gauge calculated in [L. Fister and J. M. Pawlowski, arXiv:1112.5440; L. Fister and J. M. Pawlowski, arXiv:1112.5429; L. Fister, Ph.D. thesis, Heidelberg University, 2012].
Gogonea, Valentin
This article presents a theoretical investigation of the reaction mechanism of imidazole nitration by peroxynitrite using density functional theory calculations. Understanding this reaction mechanism will help in elucidating the mechanism of guanine nitration by peroxynitrite, which is one of the assumed chemical pathways for damaging DNA in cells. This work focuses on the analysis of the potential energy surface (PES) for this reaction in the gas phase. Calculations were carried out using Hartree-Fock (HF) and density functional theory (DFT) Hamiltonians with double-zeta basis sets ranging from 6-31G(d) to 6-31++G(d,p), and the triple-zeta basis set 6-311G(d). The computational results reveal that the reaction of imidazole with peroxynitrite in gas phase produces the following species: (i) hydroxide ion and 2-nitroimidazole, (ii) hydrogen superoxide ion and 2-nitrosoimidazole, and (iii) water and 2-nitroimidazolide. The rate-determining step is the formation of a short-lived intermediate in which the imidazole C2 carbon is covalently bonded to peroxynitrite nitrogen. Three short-lived intermediates were found in the reaction path. These intermediates are involved in a proton-hopping transport from C2 carbon to the terminal oxygen of the OO moiety of peroxynitrite via the nitroso (ON) oxygen. Both HF and DFT calculations (using the Becke3-Lee-Yang-Parr functional) lead to similar reaction paths for proton transport, but the landscape details of the PES for HF and DFT calculations differ. This investigation shows that the reaction of imidazole with peroxynitrite produces essentially the same types of products (nitro- and nitroso-) as observed experimentally in the reaction of guanine with peroxynitrite, which makes the former reaction a good model to study by computation the essential characteristics of the latter reaction. Nevertheless, the computationally determined activation energy for imidazole nitration by peroxynitrite in the gas phase is 84.1 kcal
Hexagonalization of correlation functions
International Nuclear Information System (INIS)
Fleury, Thiago; Komatsu, Shota
2017-01-01
We propose a nonperturbative framework to study general correlation functions of single-trace operators in N=4 supersymmetric Yang-Mills theory at large N. The basic strategy is to decompose them into fundamental building blocks called the hexagon form factors, which were introduced earlier to study structure constants using integrability. The decomposition is akin to a triangulation of a Riemann surface, and we thus call it hexagonalization. We propose a set of rules to glue the hexagons together based on symmetry, which naturally incorporate the dependence on the conformal and the R-symmetry cross ratios. Our method is conceptually different from the conventional operator product expansion and automatically takes into account multi-trace operators exchanged in OPE channels. To illustrate the idea in simple set-ups, we compute four-point functions of BPS operators of arbitrary lengths and correlation functions of one Konishi operator and three short BPS operators, all at one loop. In all cases, the results are in perfect agreement with the perturbative data. We also suggest that our method can be a useful tool to study conformal integrals, and show it explicitly for the case of ladder integrals.
Hexagonalization of correlation functions
Energy Technology Data Exchange (ETDEWEB)
Fleury, Thiago [Instituto de Física Teórica, UNESP - University Estadual Paulista,ICTP South American Institute for Fundamental Research,Rua Dr. Bento Teobaldo Ferraz 271, 01140-070, São Paulo, SP (Brazil); Komatsu, Shota [Perimeter Institute for Theoretical Physics,31 Caroline St N Waterloo, Ontario N2L 2Y5 (Canada)
2017-01-30
We propose a nonperturbative framework to study general correlation functions of single-trace operators in N=4 supersymmetric Yang-Mills theory at large N. The basic strategy is to decompose them into fundamental building blocks called the hexagon form factors, which were introduced earlier to study structure constants using integrability. The decomposition is akin to a triangulation of a Riemann surface, and we thus call it hexagonalization. We propose a set of rules to glue the hexagons together based on symmetry, which naturally incorporate the dependence on the conformal and the R-symmetry cross ratios. Our method is conceptually different from the conventional operator product expansion and automatically takes into account multi-trace operators exchanged in OPE channels. To illustrate the idea in simple set-ups, we compute four-point functions of BPS operators of arbitrary lengths and correlation functions of one Konishi operator and three short BPS operators, all at one loop. In all cases, the results are in perfect agreement with the perturbative data. We also suggest that our method can be a useful tool to study conformal integrals, and show it explicitly for the case of ladder integrals.
Correlation Functions and Power Spectra
DEFF Research Database (Denmark)
Larsen, Jan
2006-01-01
The present lecture note is a supplement to the textbook Digital Signal Processing by J. Proakis and D.G. Manolakis used in the IMM/DTU course 02451 Digital Signal Processing and provides an extended discussion of correlation functions and power spectra. The definitions of correlation functions....... It is possible to define correlation functions and associated spectra for aperiodic, periodic and random signals although the interpretation is different. Moreover, we will discuss correlation functions when mixing these basic signal types. In addition, the note include several examples for the purpose...
Hafizi, Roohollah; Hashemifar, S Javad; Alaei, Mojtaba; Jangrouei, MohammadReza; Akbarzadeh, Hadi
2016-12-07
In this paper, we employ an evolutionary algorithm along with the full-potential density functional theory (DFT) computations to perform a comprehensive search for the stable structures of stoichiometric (WS 2 ) n nano-clusters (n = 1 - 9), within three different exchange-correlation functionals. Our results suggest that n = 5 and 8 are possible candidates for the low temperature magic sizes of WS 2 nano-clusters while at temperatures above 500 Kelvin, n = 7 exhibits a comparable relative stability with n = 8. The electronic properties and energy gap of the lowest energy isomers were computed within several schemes, including semilocal Perdew-Burke-Ernzerhof and Becke-Lee-Yang-Parr functionals, hybrid B3LYP functional, many body based DFT+GW approach, ΔSCF method, and time dependent DFT calculations. Vibrational spectra of the lowest lying isomers, computed by the force constant method, are used to address IR spectra and thermal free energy of the clusters. Time dependent density functional calculation in a real time domain is applied to determine the full absorption spectra and optical gap of the lowest energy isomers of the WS 2 nano-clusters.
Quantum Calculation for Musk Molecules Infrared Spectra towards the Understanding of Odor
Directory of Open Access Journals (Sweden)
Elaine Rose Maia
2014-01-01
Full Text Available It is not clear so far how humans can recognize odor. One of the theories regarding structure-odor relationship is vibrational theory, which claims that odors can be recognized by their modes of vibration. In this sense, this paper brings a novel comparison made between musky and nonmusky molecules, as to check the existence of correlation between their modes on the infrared spectra and odor. For this purpose, sixteen musky odorants were chosen, as well as seven other molecules that are structurally similar to them, but with no musk odor. All of them were submitted to solid theoretical methodology (using molecular mechanics/molecular dynamics and Neglect of Diatomic Differential Overlap Austin Model 1 methods to optimize geometries as to achieve density functional theory spectra information, with both Gradient Corrected Functional Perdew-Wang generalized-gradient approximation (GGA/PW91 and hybrid Becke, three-parameter, Lee-Yang-Parr (B3LYP functional. For a proper analysis over spectral data, a mathematical method was designed, generating weighted averages for theoretical frequencies and computing deviations from these averages. It was then devised that musky odorants satisfied demands of the vibrational theory, while nonmusk compounds belonging either to nitro group or to acyclic group failed to fulfill the same criteria.
Toward a Monte Carlo program for simulating vapor-liquid phase equilibria from first principles
Energy Technology Data Exchange (ETDEWEB)
McGrath, M; Siepmann, J I; Kuo, I W; Mundy, C J; Vandevondele, J; Sprik, M; Hutter, J; Mohamed, F; Krack, M; Parrinello, M
2004-10-20
Efficient Monte Carlo algorithms are combined with the Quickstep energy routines of CP2K to develop a program that allows for Monte Carlo simulations in the canonical, isobaric-isothermal, and Gibbs ensembles using a first principles description of the physical system. Configurational-bias Monte Carlo techniques and pre-biasing using an inexpensive approximate potential are employed to increase the sampling efficiency and to reduce the frequency of expensive ab initio energy evaluations. The new Monte Carlo program has been validated through extensive comparison with molecular dynamics simulations using the programs CPMD and CP2K. Preliminary results for the vapor-liquid coexistence properties (T = 473 K) of water using the Becke-Lee-Yang-Parr exchange and correlation energy functionals, a triple-zeta valence basis set augmented with two sets of d-type or p-type polarization functions, and Goedecker-Teter-Hutter pseudopotentials are presented. The preliminary results indicate that this description of water leads to an underestimation of the saturated liquid density and heat of vaporization and, correspondingly, an overestimation of the saturated vapor pressure.
Energy Technology Data Exchange (ETDEWEB)
McGrath, M; Siepmann, J I; Kuo, I W; Mundy, C J; VandeVondele, J; Hutter, J; Mohamed, F; Krack, M
2004-12-02
A series of first principles Monte Carlo simulations in the isobaric-isothermal ensemble were carried out for liquid water at ambient conditions (T = 298 K and p = 1 atm). The Becke-Lee-Yang-Parr (BLYP) exchange and correlation energy functionals and norm-conserving Goedecker-Teter-Hutter (GTH) pseudopotentials were employed with the CP2K simulation package to examine systems consisting of 64 water molecules. The fluctuations in the system volume encountered in simulations in the isobaric-isothermal ensemble requires a reconsideration of the suitability of the typical charge density cutoff and the regular grid generation method previously used for the computation of the electrostatic energy in first principles simulations in the microcanonical or canonical ensembles. In particular, it is noted that a much higher cutoff is needed and that the most computationally efficient method of creating grids can result in poor simulations. Analysis of the simulation trajectories using a very large charge density cutoff at 1200 Ry and four different grid generation methods point to a substantially underestimated liquid density of about 0.85 g/cm{sup 3} resulting in a somewhat understructured liquid (with a value of about 2.7 for the height of the first peak in the oxygen/oxygen radial distribution function) for BLYP-GTH water at ambient conditions.
Singh, Nitin Kumar; Satpathi, Bishnupada; Balanarayan, P; Ramasastry, S S V
2017-12-13
The intramolecular Morita-Baylis-Hillman reaction of β-mono and β,β-disubstituted enones shows high yields and stereo-selective products when the reaction is performed in the presence of 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) as a solvent. In this work, we carried out a computational study using the density functional Becke 3-(B3) parameter exchange and the Lee-Yang-Parr (LYP) correlation functional and 6-31+G* basis set. Two major steps i.e. C-C bond formation and proton transfer were analysed using different pathways. The calculations show a very low barrier (ΔG † = 0.23 kcal mol -1 ) for C-C bond formation in the case of an experimentally dominant product. For this pathway the subsequent proton transfer via the HFIP step has a barrier of 26.98 kcal mol -1 . The same has been confirmed using a Molecular Electrostatic Potential (MESP), which shows a negative region in between CC in the transition state. In spite of high barriers for proton transfer, the intermediate products formed in this reaction pathway are thermodynamically more stable in comparison with other pathways. The thermodynamic stability of the final product in this pathway is observed to surpass all other effects in the presence of HFIP, thereby corroborating the experimentally observed enantioselectivity.
Directory of Open Access Journals (Sweden)
Morteza Montazerozohori
2013-01-01
Full Text Available Synthesis of zinc(II/cadmium(II/mercury(II thiocyanate and azide complexes of a new bidentate Schiff-base ligand (L with general formula of MLX2 (M = Zn(II, Cd(II, and Hg(II in ethanol solution at room temperature is reported. The ligand and metal complexes were characterized by using ultraviolet-visible (UV-visible, Fourier transform infrared (FT-IR, 1H- and 13C-NMR spectroscopy and physical characterization, CHN analysis, and molar conductivity. 1H- and 13C-NMR spectra have been studied in DMSO-d6. The reasonable shifts of FT-IR and NMR spectral signals of the complexes with respect to the free ligand confirm well coordination of Schiff-base ligand and anions in an inner sphere coordination space. The conductivity measurements as well as spectral data indicated that the complexes are nonelectrolyte. Theoretical optimization on the structure of ligand and its complexes was performed at the Becke’s three-parameter hybrid functional (B3 with the nonlocal correlation of Lee-Yang-Parr (LYP level of theory with double-zeta valence (LANL2DZ basis set using GAUSSIAN 03 suite of program, and then some theoretical structural parameters such as bond lengths, bond angles, and torsion angles were obtained. Finally, electrochemical behavior of ligand and its complexes was investigated. Cyclic voltammograms of metal complexes showed considerable changes with respect to free ligand.
Scattering function S (Q, w), correlation functions
International Nuclear Information System (INIS)
Binder, K.
1978-01-01
The following subjects are dealt with in this paper: 1) Two-Particle problem in quantum mechanics and inelastic scattering 2) The doubly differential cross section for many-particle systems 3) The van Hove transformation and the scattering funktion S (Q, w) 4) Relation between scattering functions and correlation functions 5) Examples: ideal gas, liquids 6) Differential cross section, sum rules, convolution approximation. (orig.) [de
Atomic structures and covalent-to-metallic transition of lead clusters Pbn (n=2-22)
International Nuclear Information System (INIS)
Wang Baolin; Zhao Jijun; Chen Xiaoshuang; Shi Daning; Wang Guanghou
2005-01-01
The lowest-energy structures and electronic properties of the lead clusters are studied by density-functional-theory calculations with Becke-Lee-Yang-Parr gradient correction. The lowest-energy structures of Pb n (n=2-22) clusters are determined from a number of structural isomers, which are generated from empirical genetic algorithm simulations. The competition between atom-centered compact structures and layered stacking structures leads to the alternative appearance of the two types of structures as global minimum. The size evolution of geometric and electronic properties from covalent bonding towards bulk metallic behavior in Pb clusters is discussed
Short time behaviour of density correlation functions
Konijnendijk, H.H.U.
1977-01-01
In this thesis the dynamical behaviour of the atoms in a fluid or gas is studied with time dependent correlation functions as the density-density correlation function and the velocity autocorrelation function. Theoretically it is not possible to calculate these correlation functions exactly for the
Using correlation functions as free decays
DEFF Research Database (Denmark)
Brincker, Rune; Amador, Sandro; Juul, Martin
It is a general assumption in OMA that correlation functions are free decays. In multiple input OMA this assumption also implies that any column in the correlation function matrix is to be considered as multiple output free decays. This assumption is discussed in this paper together with issues...... concerning estimation and application of correlations functions in OMA....
Energy Correlation Functions for Jet Substructure
Larkoski, Andrew J; Thaler, Jesse
2013-01-01
We show how generalized energy correlation functions can be used as a powerful probe of jet substructure. These correlation functions are based on the energies and pair-wise angles of particles within a jet, with (N+1)-point correlators sensitive to N-prong substructure. Unlike many previous jet substructure methods, these correlation functions do not require the explicit identification of subjet regions. In addition, the correlation functions are better probes of certain soft and collinear features that are masked by other methods. We present three Monte Carlo case studies to illustrate the utility of these observables: 2-point correlators for quark/gluon discrimination, 3-point correlators for boosted W/Z/Higgs boson identification, and 4-point correlators for boosted top quark identification. For quark/gluon discrimination, the 2-point correlator is particularly powerful, as can be understood via a next-to-leading logarithmic calculation. For boosted 2-prong resonances the benefit depends on the mass of th...
Magnetic properties and core electron binding energies of liquid water
Galamba, N.; Cabral, Benedito J. C.
2018-01-01
The magnetic properties and the core and inner valence electron binding energies of liquid water are investigated. The adopted methodology relies on the combination of molecular dynamics and electronic structure calculations. Born-Oppenheimer molecular dynamics with the Becke and Lee-Yang-Parr functionals for exchange and correlation, respectively, and includes an empirical correction (BLYP-D3) functional and classical molecular dynamics with the TIP4P/2005-F model were carried out. The Keal-Tozer functional was applied for predicting magnetic shielding and spin-spin coupling constants. Core and inner valence electron binding energies in liquid water were calculated with symmetry adapted cluster-configuration interaction. The relationship between the magnetic shielding constant σ(17O), the role played by the oxygen atom as a proton acceptor and donor, and the tetrahedral organisation of liquid water are investigated. The results indicate that the deshielding of the oxygen atom in water is very dependent on the order parameter (q) describing the tetrahedral organisation of the hydrogen bond network. The strong sensitivity of magnetic properties on changes of the electronic density in the nuclei environment is illustrated by a correlation between σ(17O) and the energy gap between the 1a1[O1s] (core) and the 2a1 (inner valence) orbitals of water. Although several studies discussed the eventual connection between magnetic properties and core electron binding energies, such a correlation could not be clearly established. Here, we demonstrate that for liquid water this correlation exists although involving the gap between electron binding energies of core and inner valence orbitals.
From correlation functions to event shapes
Belitsky, A V; Korchemsky, G P; Sokatchev, E; Zhiboedov, A
2014-01-01
We present a new approach to computing event shape distributions or, more precisely, charge flow correlations in a generic conformal field theory (CFT). These infrared finite observables are familiar from collider physics studies and describe the angular distribution of global charges in outgoing radiation created from the vacuum by some source. The charge flow correlations can be expressed in terms of Wightman correlation functions in a certain limit. We explain how to compute these quantities starting from their Euclidean analogues by means of a non-trivial analytic continuation which, in the framework of CFT, can elegantly be performed in Mellin space. The relation between the charge flow correlations and Euclidean correlation functions can be reformulated directly in configuration space, bypassing the Mellin representation, as a certain Lorentzian double discontinuity of the correlation function integrated along the cuts. We illustrate the general formalism in N=4 SYM, making use of the well-known results...
Bootstrapping correlation functions in N=4 SYM
Chicherin, Dmitry; Eden, Burkhard; Heslop, Paul; Korchemsky, Gregory P; Sokatchev, Emery
2016-01-01
We describe a new approach to computing the chiral part of correlation functions of stress-tensor supermultiplets in N=4 SYM that relies on symmetries, analytic properties and the structure of the OPE only. We demonstrate that the correlation functions are given by a linear combination of chiral N=4 superconformal invariants accompanied by coefficient functions depending on the space-time coordinates only. We present the explicit construction of these invariants and show that the six-point correlation function is fixed in the Born approximation up to four constant coefficients by its symmetries. In addition, the known asymptotic structure of the correlation function in the light-like limit fixes unambiguously these coefficients up to an overall normalization. We demonstrate that the same approach can be applied to obtain a representation for the six-point NMHV amplitude that is free from any auxiliary gauge fixing parameters, does not involve spurious poles and manifests half of the dual superconformal symmet...
Noninvasive measurement of dynamic correlation functions
CSIR Research Space (South Africa)
Uhrich, P
2017-08-01
Full Text Available )spin systems and arbitrary equilibrium or nonequilibrium initial states. Different choices of the coupling operator give access to the real and imaginary parts of the dynamic correlation function. This protocol reduces disturbances due to the early...
Liquid Water from First Principles: Validation of Different Sampling Approaches
Energy Technology Data Exchange (ETDEWEB)
Mundy, C J; Kuo, W; Siepmann, J; McGrath, M J; Vondevondele, J; Sprik, M; Hutter, J; Parrinello, M; Mohamed, F; Krack, M; Chen, B; Klein, M
2004-05-20
A series of first principles molecular dynamics and Monte Carlo simulations were carried out for liquid water to assess the validity and reproducibility of different sampling approaches. These simulations include Car-Parrinello molecular dynamics simulations using the program CPMD with different values of the fictitious electron mass in the microcanonical and canonical ensembles, Born-Oppenheimer molecular dynamics using the programs CPMD and CP2K in the microcanonical ensemble, and Metropolis Monte Carlo using CP2K in the canonical ensemble. With the exception of one simulation for 128 water molecules, all other simulations were carried out for systems consisting of 64 molecules. It is found that the structural and thermodynamic properties of these simulations are in excellent agreement with each other as long as adiabatic sampling is maintained in the Car-Parrinello molecular dynamics simulations either by choosing a sufficiently small fictitious mass in the microcanonical ensemble or by Nos{acute e}-Hoover thermostats in the canonical ensemble. Using the Becke-Lee-Yang-Parr exchange and correlation energy functionals and norm-conserving Troullier-Martins or Goedecker-Teter-Hutter pseudopotentials, simulations at a fixed density of 1.0 g/cm{sup 3} and a temperature close to 315 K yield a height of the first peak in the oxygen-oxygen radial distribution function of about 3.0, a classical constant-volume heat capacity of about 70 J K{sup -1} mol{sup -1}, and a self-diffusion constant of about 0.1 Angstroms{sup 2}/ps.
Characterizing Ni(II) hydration in aqueous solution using DFT and EXAFS.
Liu, H Y; Fang, C H; Fang, Y; Zhou, Y Q; Ge, H W; Zhu, F Y; Sun, P C; Miao, J T
2016-01-01
In the present work, a detailed investigation of Ni(II) hydration in water solutions was carried out using density functional theory (DFT) and extended X-ray absorption fine structure (EXAFS) spectroscopy. The hydrated characteristics of [Ni(H2O)n](2+) clusters, such as energy parameters, atomic charge distributions, and bond parameters, were explored using DFT with Becke's three-parameter exchange potential and the Lee-Yang-Parr correlation functional (B3LYP). DFT calculations indicated that the preferred structure of the first hydration shell of Ni(II) generally has a coordination number of six and is almost unaffected by the water molecules in the outer solvation shell, whereas the structure of the second solvation shell varies as the hydration proceeds. EXAFS measurements are reported for aqueous NiSO4 and Ni(NO3)2 solutions and the Ni(NO3)2·6H2O crystal. Analysis of the EXAFS spectra of these three systems using a multiparameter fitting procedure showed that, in each case, the first coordination shell consists of six water molecules with a Ni-O coordination distance of 2.04 Å, and that there is no Ni-S or Ni-N coordination in the first shell. There was no evidence of outer-shell SO4(2-) or NO3(-) ions substituting inner-sphere water molecules in NiSO4 and Ni(NO3)2. The characteristics of Ni(II) hydration obtained from DFT calculations agreed well with those obtained experimentally using EXAFS.
Ong, S. W.; Lee, B. X. B.; Kang, H. C.
2011-09-01
We have performed Car-Parrinello molecular dynamics (CPMD) calculations of the hydrogen-bonded NH3-HCl dimer. Our main aim is to establish how ionic-orbital coupling in CPMD affects the vibrational dynamics in hydrogen-bonded systems by characterizing the dependence of the calculated vibrational frequencies upon the orbital mass in the adiabatic limit of Car-Parrinello calculations. We use the example of the NH3-HCl dimer because of interest in its vibrational spectrum, in particular the magnitude of the frequency shift of the H-Cl stretch due to the anharmonic interactions when the hydrogen bond is formed. We find that an orbital mass of about 100 a.u. or smaller is required in order for the ion-orbital coupling to be linear in orbital mass, and the results for which can be accurately extrapolated to the adiabatic limit of zero orbital mass. We argue that this is general for hydrogen-bonded systems, suggesting that typical orbital mass values used in CPMD are too high to accurately describe vibrational dynamics in hydrogen-bonded systems. Our results also show that the usual application of a scaling factor to the CPMD frequencies to correct for the effects of orbital mass is not valid. For the dynamics of the dimer, we find that the H-Cl stretch and the N-H-Cl bend are significantly coupled, suggesting that it is important to include the latter degree of freedom in quantum dynamical calculations. Results from our calculations with deuterium-substitution show that both these degrees of freedom have significant anharmonic interactions. Our calculated frequency for the H-Cl stretch using the Becke-exchange Lee-Yang-Parr correlation functional compares reasonably well with a previous second-order Møller-Plesset calculation with anharmonic corrections, although it is low compared to the experimental value for the dimer trapped in a neon-matrix.
Mushtaque, Md.; Avecilla, Fernando; Khan, Md. Shahzad; Hafeez, Zubair Bin; Rezvi, M. Moshahid A.; Srivastava, Anurag
2017-08-01
Thiourea derivative,3-(4-methoxyphenyl)-1-(pyridin-2-ylmethyl)thiourea, was synthesized. The structure of the synthesized compound (3) was elucidated by IR, UV-visible, 1H NMR, mass Spectrometry, and X-ray single crystal structure. The computational quantum chemical studies like, IR, UV, NBO analysis were performed by DFT with Becke-3-Lee-Yang- Parr (B3LYP) exchange-correlation functional in combination with 6-311++G(d,p) basis sets. It was observed experimentally and theoretically that compound (3) exhibited syn-anti-conformation around sulphur atom. The DNA-binding constant Kb was found 3.3 × 106 Lmol-1. The docking energy of compound (3) with 1BNA was found -6.2 kcal/mol. MTT-assay against HepG2 (IC50 = 140.39) and Siha (IC50 = 119.87 μM) cell lines revealed that compound (3) wasnon-toxic up to140.39 μM against HepG2 and 119.87 μM against Siha cells respectively. It was also found that compound (3) is non-toxic against normal human cell line HEK-293(IC50 = 148.67 μM). Cell cycle analyses displayed that treated HepG2 cells at 40 μM and 80 μM showed 65% and 70% arrest in G0/G1with respect to untreated controls (60%) and Siha cells at the same concentration displayed 59% and 65% arrest with respect to G0/G1 as compared to untreated control (45%).
Correlation functions of two-matrix models
International Nuclear Information System (INIS)
Bonora, L.; Xiong, C.S.
1993-11-01
We show how to calculate correlation functions of two matrix models without any approximation technique (except for genus expansion). In particular we do not use any continuum limit technique. This allows us to find many solutions which are invisible to the latter technique. To reach our goal we make full use of the integrable hierarchies and their reductions which were shown in previous papers to naturally appear in multi-matrix models. The second ingredient we use, even though to a lesser extent, are the W-constraints. In fact an explicit solution of the relevant hierarchy, satisfying the W-constraints (string equation), underlies the explicit calculation of the correlation functions. The correlation functions we compute lend themselves to a possible interpretation in terms of topological field theories. (orig.)
Correlation functions of Coulomb branch operators
Energy Technology Data Exchange (ETDEWEB)
Gerchkovitz, Efrat [Weizmann Institute of Science,Rehovot 76100 (Israel); Gomis, Jaume [Perimeter Institute for Theoretical Physics,Waterloo, ON N2L 2Y5 (Canada); Ishtiaque, Nafiz [Perimeter Institute for Theoretical Physics,Waterloo, ON N2L 2Y5 (Canada); Department of Physics, University of Waterloo,Waterloo, ON N2L 3G1 (Canada); Karasik, Avner; Komargodski, Zohar [Weizmann Institute of Science,Rehovot 76100 (Israel); Pufu, Silviu S. [Joseph Henry Laboratories, Princeton University,Princeton, NJ 08544 (United States)
2017-01-24
We consider the correlation functions of Coulomb branch operators in four-dimensional N=2 Superconformal Field Theories (SCFTs) involving exactly one anti-chiral operator. These extremal correlators are the “minimal' non-holomorphic local observables in the theory. We show that they can be expressed in terms of certain determinants of derivatives of the four-sphere partition function of an appropriate deformation of the SCFT. This relation between the extremal correlators and the deformed four-sphere partition function is non-trivial due to the presence of conformal anomalies, which lead to operator mixing on the sphere. Evaluating the deformed four-sphere partition function using supersymmetric localization, we compute the extremal correlators explicitly in many interesting examples. Additionally, the representation of the extremal correlators mentioned above leads to a system of integrable differential equations. We compare our exact results with previous perturbative computations and with the four-dimensional tt{sup ∗} equations. We also use our results to study some of the asymptotic properties of the perturbative series expansions we obtain in N=2 SQCD.
From correlation functions to scattering amplitudes
Eden, Burkhard; Korchemsky, Gregory P.; Sokatchev, Emery
2011-12-01
We study the correlation functions of half-BPS protected operators in mathcal{N} = {4} super-Yang-Mills theory, in the limit where the positions of adjacent operators become light-like separated. We compute the loop corrections by means of Lagrangian insertions. The divergences resulting from the light-cone limit are regularized by changing the dimension of the integration measure over the insertion points. Switching from coordinates to dual momenta, we show that the logarithm of the correlation function is identical with twice the logarithm of the matching MHV gluon scattering amplitude. We present a number of examples of this new relation, at one and two loops.
Non-Parametric Estimation of Correlation Functions
DEFF Research Database (Denmark)
Brincker, Rune; Rytter, Anders; Krenk, Steen
In this paper three methods of non-parametric correlation function estimation are reviewed and evaluated: the direct method, estimation by the Fast Fourier Transform and finally estimation by the Random Decrement technique. The basic ideas of the techniques are reviewed, sources of bias are point...... out, and methods to prevent bias are presented. The techniques are evaluated by comparing their speed and accuracy on the simple case of estimating auto-correlation functions for the response of a single degree-of-freedom system loaded with white noise....
Locality of correlation in density functional theory.
Burke, Kieron; Cancio, Antonio; Gould, Tim; Pittalis, Stefano
2016-08-07
The Hohenberg-Kohn density functional was long ago shown to reduce to the Thomas-Fermi (TF) approximation in the non-relativistic semiclassical (or large-Z) limit for all matter, i.e., the kinetic energy becomes local. Exchange also becomes local in this limit. Numerical data on the correlation energy of atoms support the conjecture that this is also true for correlation, but much less relevant to atoms. We illustrate how expansions around a large particle number are equivalent to local density approximations and their strong relevance to density functional approximations. Analyzing highly accurate atomic correlation energies, we show that EC → -AC ZlnZ + BCZ as Z → ∞, where Z is the atomic number, AC is known, and we estimate BC to be about 37 mhartree. The local density approximation yields AC exactly, but a very incorrect value for BC, showing that the local approximation is less relevant for the correlation alone. This limit is a benchmark for the non-empirical construction of density functional approximations. We conjecture that, beyond atoms, the leading correction to the local density approximation in the large-Z limit generally takes this form, but with BC a functional of the TF density for the system. The implications for the construction of approximate density functionals are discussed.
Integral equations of hadronic correlation functions a functional- bootstrap approach
Manesis, E K
1974-01-01
A reasonable 'microscopic' foundation of the Feynman hadron-liquid analogy is offered, based on a class of models for hadron production. In an external field formalism, the equivalence (complementarity) of the exclusive and inclusive descriptions of hadronic reactions is specifically expressed in a functional-bootstrap form, and integral equations between inclusive and exclusive correlation functions are derived. Using the latest CERN-ISR data on the two-pion inclusive correlation function, and assuming rapidity translational invariance for the exclusive one, the simplest integral equation is solved in the 'central region' and an exclusive correlation length in rapidity predicted. An explanation is also offered for the unexpected similarity observed between pi /sup +/ pi /sup -/ and pi /sup -/ pi /sup -/ inclusive correlations. (31 refs).
Matrix elements from moments of correlation functions
Energy Technology Data Exchange (ETDEWEB)
Chang, Chia Cheng [SLAC National Accelerator Lab., Menlo Park, CA (United States); Bouchard, Chris [College of William and Mary, Williamsburg, VA (United States); Orginos, Konstantinos [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); College of William and Mary, Williamsburg, VA (United States); Richards, David G. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)
2016-10-01
Momentum-space derivatives of matrix elements can be related to their coordinate-space moments through the Fourier transform. We derive these expressions as a function of momentum transfer Q2 for asymptotic in/out states consisting of a single hadron. We calculate corrections to the finite volume moments by studying the spatial dependence of the lattice correlation functions. This method permits the computation of not only the values of matrix elements at momenta accessible on the lattice, but also the momentum-space derivatives, providing {\\it a priori} information about the Q2 dependence of form factors. As a specific application we use the method, at a single lattice spacing and with unphysically heavy quarks, to directly obtain the slope of the isovector form factor at various Q2, whence the isovector charge radius. The method has potential application in the calculation of any hadronic matrix element with momentum transfer, including those relevant to hadronic weak decays.
Probing multimode squeezing with correlation functions
Energy Technology Data Exchange (ETDEWEB)
Christ, Andreas; Silberhorn, Christine [Applied Physics, University of Paderborn, Warburger Strasse 100, 33098 Paderborn (Germany); Laiho, Kaisa; Eckstein, Andreas; Cassemiro, Katiuscia N, E-mail: Andreas.Christ@uni-paderborn.de [Max Planck Institute for the Science of Light, Guenther-Scharowsky Strasse 1/Bau 24, 91058 Erlangen (Germany)
2011-03-15
Broadband multimode squeezers constitute a powerful quantum resource with promising potential for different applications in quantum information technologies such as information coding in quantum communication networks or quantum simulations in higher-dimensional systems. However, the characterization of a large array of squeezers that coexist in a single spatial mode is challenging. In this paper, we address this problem and propose a straightforward method for determining the number of squeezers and their respective squeezing strengths by using broadband multimode correlation function measurements. These measurements employ the large detection windows of the state of the art avalanche photodiodes in order to simultaneously probe the full Hilbert space of the generated state, which enables us to benchmark the squeezed states. Moreover, due to the structure of correlation functions, our measurements are not affected by losses. This is a significant advantage, since detectors with low efficiencies are sufficient. Our approach is less costly than tomographic methods relying on multimode homodyne detection, which is based on much more demanding measurement and analysis tools and appear to be impractical for large Hilbert spaces.
Two-point correlation function for Dirichlet L-functions
Bogomolny, E.; Keating, J. P.
2013-03-01
The two-point correlation function for the zeros of Dirichlet L-functions at a height E on the critical line is calculated heuristically using a generalization of the Hardy-Littlewood conjecture for pairs of primes in arithmetic progression. The result matches the conjectured random-matrix form in the limit as E → ∞ and, importantly, includes finite-E corrections. These finite-E corrections differ from those in the case of the Riemann zeta-function, obtained in Bogomolny and Keating (1996 Phys. Rev. Lett. 77 1472), by certain finite products of primes which divide the modulus of the primitive character used to construct the L-function in question.
Tarannum, N.; Singh, M.
2014-12-01
New biologically active coumarin derivative, substituted xanthene-dione was synthesized by an easy, facile, cost-effective and efficient method from dimedone and diethylene glycol diacrylate without use of expensive and hazardous catalyst. The synthesis is simple, short, high-yielding and moreover does not require expensive solvents. The compound was characterized by IR, NMR and X-ray crystallography study. DFT (Density Functional Theory) calculations were performed at Becke's three-parameter functional and Lee-Yang-Parr functional (B3LYP) level of calculation and the 6-31G++ basis set was used for ground state geometry optimization. A comparison of the selected bond lengths and bond angles of the crystal structure and theoretically optimized structure by DFT have shown good agreement. The DFT study of electron surface potential (ESP), showed a large intramolecular charge transfer efficiency of the molecule indicating optical activity of xanthene dione.
Meson's correlation functions in a nuclear medium
Directory of Open Access Journals (Sweden)
Chanyong Park
2016-09-01
Full Text Available We investigate meson's spectrum, decay constant and form factor in a nuclear medium through holographic two- and three-point correlation functions. To describe a nuclear medium composed of protons and neutrons, we consider a hard wall model on the thermal charged AdS geometry and show that due to the isospin interaction with a nuclear medium, there exist splittings of the meson's spectrum, decay constant and form factor relying on the isospin charge. In addition, we show that the ρ-meson's form factor describing an interaction with pseudoscalar fluctuation decreases when the nuclear density increases, while the interaction with a longitudinal part of an axial vector meson increases.
Structure–function correlations in tyrosinases
Kanteev, Margarita; Goldfeder, Mor; Fishman, Ayelet
2015-01-01
Tyrosinases are metalloenzymes belonging to the type-3 copper protein family which contain two copper ions in the active site. They are found in various prokaryotes as well as in plants, fungi, arthropods, and mammals and are responsible for pigmentation, wound healing, radiation protection, and primary immune response. Tyrosinases perform two sequential enzymatic reactions: hydroxylation of monophenols and oxidation of diphenols to form quinones which polymerize spontaneously to melanin. Two other members of this family are catechol oxidases, which are prevalent mainly in plants and perform only the second oxidation step, and hemocyanins, which lack enzymatic activity and are oxygen carriers. In the last decade, several structures of plant and bacterial tyrosinases were determined, some with substrates or inhibitors, highlighting features and residues which are important for copper uptake and catalysis. This review summarizes the updated information on structure–function correlations in tyrosinases along with comparison to other type-3 copper proteins. PMID:26104241
Theoretical investigations of the bulk modulus in the tetra-cubic transition of PbTiO3 material
Directory of Open Access Journals (Sweden)
Renan A. P. Ribeiro
2014-01-01
Full Text Available Resulting from ion displacement in a solid under pressure, piezoelectricity is an electrical polarization that can be observed in perovskite-type electronic ceramics, such as PbTiO3, which present cubic and tetragonal symmetries at different pressures. The transition between these crystalline phases is determined theoretically through the bulk modulus from the relationship between material energy and volume. However, the change in the material molecular structure is responsible for the piezoelectric effect. In this study, density functional theory calculations using the Becke 3-Parameter-Lee-Yang-Parr hybrid functional were employed to investigate the structure and properties associated with the transition state of the tetragonal-cubic phase change in PbTiO3 material.
FUNCTIONAL CORRELATION OF FP AND DC METHODS
Directory of Open Access Journals (Sweden)
Marin Kaluža
2013-02-01
Full Text Available Most of organizations today use information-communication technologies (ICT for building an information system (IS. IS is assembled of hardware, software, network resources, organizational and human resources. In IS development process, complexity is crucial for evaluating quantities of resources needed (time, people, money, equipment. Complexity of an IS can be evaluated and/or measured in different phases of development. There are many methods for measuring complexity, but mostly used and thoroughly described method is Function Point Analysis (FP. The opposite method, Database Complexity (DC, does not measure all the aspects of IS, but it could evaluate system complexity depending on the database complexity. DC method is intended to be used for measuring semantic complexity of the IS database, and can be shown by counting attributes A and foreign keys F. This paper describes a very high correlation between FP and DC methods, and defines a function which can in 95% of accuracy express FP values from measured DC values.
Electronic properties of one-dimensional C36 polymers
International Nuclear Information System (INIS)
Huang Yuanhe; Du Shixuan; Chen Yuanmei; Li Yuxue; Liu Ruozhuang
2002-01-01
Electronic structures for several neutral and anionic one-dimensional (1D) C 36 polymers are investigated by using the ab initio self-consistent-field crystal orbital method based on the B3LYP (Becke-Lee-Yang-Parr) density functional theory. Calculations show that all the neutral polymers are semiconductors with energy gaps in the range from 0.55 to 2.04 eV. The possibilities of superconducting and Peierls phase transitions are also explored for these metallic anionic polymers at the same time. It is found that the intramolecular electron-phonon (e-p) coupling in metallic 1D C 36 polymers plays an important role in producing high superconducting transition temperatures (T c ). The estimated Peierls phase transition temperatures (T p ) are very small due to the very weak intermolecular e-p interactions. (author)
A cumulant functional for static and dynamic correlation
International Nuclear Information System (INIS)
Hollett, Joshua W.; Hosseini, Hessam; Menzies, Cameron
2016-01-01
A functional for the cumulant energy is introduced. The functional is composed of a pair-correction and static and dynamic correlation energy components. The pair-correction and static correlation energies are functionals of the natural orbitals and the occupancy transferred between near-degenerate orbital pairs, rather than the orbital occupancies themselves. The dynamic correlation energy is a functional of the statically correlated on-top two-electron density. The on-top density functional used in this study is the well-known Colle-Salvetti functional. Using the cc-pVTZ basis set, the functional effectively models the bond dissociation of H 2 , LiH, and N 2 with equilibrium bond lengths and dissociation energies comparable to those provided by multireference second-order perturbation theory. The performance of the cumulant functional is less impressive for HF and F 2 , mainly due to an underestimation of the dynamic correlation energy by the Colle-Salvetti functional.
Peculiar motions of galaxy clusters: correlation function approach
Iqbal, Naseer; Masood, Tabasum; Hamid, Mubashir; Ahmad, Naveel; Maqbool, Bari
2014-10-01
The correlation function theory on the basis of prescribed boundary conditions provides a deeper understanding in studying the dynamical parameters of galaxy clusters. The approach approximates that the moderate dense systems discussed by a two point correlation function is helpful for describing the dynamical nature of galaxy clusters. The projected theory of two point correlation function for point mass and extended mass structures can be used an alternative tool in measuring the average peculiar motion and temperature profile of galaxy clusters.
On the application of correlation function matrices in OMA
DEFF Research Database (Denmark)
Brincker, Rune
2017-01-01
In this paper the theoretical solution for the correlation function matrix of the random response of a structural system is re-visited. It is shown that using the classical definition of the correlation functions, the row space is defined by the mode shapes of the system, whereas the column space...
Holographic correlation functions in Critical Gravity
Anastasiou, Giorgos; Olea, Rodrigo
2017-11-01
We compute the holographic stress tensor and the logarithmic energy-momentum tensor of Einstein-Weyl gravity at the critical point. This computation is carried out performing a holographic expansion in a bulk action supplemented by the Gauss-Bonnet term with a fixed coupling. The renormalization scheme defined by the addition of this topological term has the remarkable feature that all Einstein modes are identically cancelled both from the action and its variation. Thus, what remains comes from a nonvanishing Bach tensor, which accounts for non-Einstein modes associated to logarithmic terms which appear in the expansion of the metric. In particular, we compute the holographic 1-point functions for a generic boundary geometric source.
Correlations and functional connections in a population of grid cells
Dunn, Benjamin; Mørreaunet, Maria; Roudi, Yasser
2014-01-01
We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a maximum entropy kinetic pairwise model (kinetic Ising model), study their functional connectivity. Even when we account for the covariations in firing rates due to overlapping fields, both the pairwise correlations and functional connections decay as a function of the shortest distance between the vertices of the spatial firi...
TreeCorr: Two-point correlation functions
Jarvis, Mike
2015-08-01
TreeCorr efficiently computes two-point correlation functions. It can compute correlations of regular number counts, weak lensing shears, or scalar quantities such as convergence or CMB temperature fluctuations. Two-point correlations may be auto-correlations or cross-correlations, including any combination of shear, kappa, and counts. Two-point functions can be done with correct curved-sky calculation using RA, Dec coordinates, on a Euclidean tangent plane, or in 3D using RA, Dec and a distance. The front end is written in Python, which can be used as a Python module or as a standalone executable using configuration files; the actual computation of the correlation functions is done in C++ using ball trees (similar to kd trees), making the calculation extremely efficient, and when available, OpenMP is used to run in parallel on multi-core machines.
Estimation of Correlation Functions by the Random Decrement Technique
DEFF Research Database (Denmark)
Brincker, Rune; Krenk, Steen; Jensen, Jacob Laigaard
1991-01-01
The Random Decrement (RDD) Technique is a versatile technique for characterization of random signals in the time domain. In this paper a short review of the theoretical basis is given, and the technique is illustrated by estimating auto-correlation functions and cross-correlation functions on modal...... responses simulated by two SDOF ARMA models loaded by the same band-limited white noise. The speed and the accuracy of the RDD technique is compared to the Fast Fourier Transform (FFT) technique. The RDD technique does not involve multiplications, but only additions. Therefore, the technique is very fast...... - in some cases up to 100 times faster than the FFT technique. Another important advantage is that if the RDD technique is implemented correctly, the correlation function estimates are unbiased. Comparison with exact solutions for the correlation functions shows that the RDD auto-correlation estimates...
Understanding volatility correlation behavior with a magnitude cross-correlation function
Jun, Woo Cheol; Oh, Gabjin; Kim, Seunghwan
2006-06-01
We propose an approach for analyzing the basic relation between correlation properties of the original signal and its magnitude fluctuations by decomposing the original signal into its positive and negative fluctuation components. We use this relation to understand the following phenomenon found in many naturally occurring time series: the magnitude of the signal exhibits long-range correlation, whereas the original signal is short-range correlated. The applications of our approach to heart rate variability signals and high-frequency foreign exchange rates reveal that the difference between the correlation properties of the original signal and its magnitude fluctuations is induced by the time organization structure of the correlation function between the magnitude fluctuations of positive and negative components. We show that this correlation function can be described well by a stretched-exponential function and is related to the nonlinearity and the multifractal structure of the signals.
Gauge-invariant correlation functions in light-cone superspace
Ananth, Sudarshan; Kovacs, Stefano; arikh, Sarthak
2012-05-01
We initiate a study of correlation functions of gauge-invariant operators in {N} = 4 super Yang-Mills theory using the light-cone superspace formalism. Our primary aim is to develop efficient methods to compute perturbative corrections to correlation functions. This analysis also allows us to examine potential subtleties which may arise when calculating off-shell quantities in light-cone gauge. We comment on the intriguing possibility that the manifest {N} = 4 supersymmetry in this approach may allow for a compact description of entire multiplets and their correlation functions.
Correlation functions of atomic nuclei in lattice QCD
Energy Technology Data Exchange (ETDEWEB)
Fodor, Zoltan [Department of Physics, Bergische Universitaet Wuppertal (Germany); Institute for Theoretical Physics, Eoetvoes University, Budapest (Hungary); Juelich Supercomputing Centre, Forschungszentrum Juelich (Germany); Guenther, Jana; Toth, Balint; Varnhorst, Lukas [Department of Physics, Bergische Universitaet Wuppertal (Germany)
2012-07-01
To determine the mass of the atomic nuclei in lattice QCD one has to calculate the correlation function of suitable combinations of quark field operators. However the calculation of this correlation functions requires to evaluate a large number of Wick contractions which scales as the factorial of the number of nucleons in the system. We explore the possibilities to reduce the computational effort for such evaluations by exploiting certain symmetries of the systems. We discuss a recursive approach which respects these symmetries and may allow the determination of the correlation function in significantly less computer time.
Universality of correlation functions in random matrix models of QCD
International Nuclear Information System (INIS)
Jackson, A.D.; Sener, M.K.; Verbaarschot, J.J.M.
1997-01-01
We demonstrate the universality of the spectral correlation functions of a QCD inspired random matrix model that consists of a random part having the chiral structure of the QCD Dirac operator and a deterministic part which describes a schematic temperature dependence. We calculate the correlation functions analytically using the technique of Itzykson-Zuber integrals for arbitrary complex supermatrices. An alternative exact calculation for arbitrary matrix size is given for the special case of zero temperature, and we reproduce the well-known Laguerre kernel. At finite temperature, the microscopic limit of the correlation functions are calculated in the saddle-point approximation. The main result of this paper is that the microscopic universality of correlation functions is maintained even though unitary invariance is broken by the addition of a deterministic matrix to the ensemble. (orig.)
CSIR Research Space (South Africa)
Kok, S
2012-07-01
Full Text Available This study reports on the asymptotic behavior of the maximum likelihood function, encountered when constructing Kriging approximations using the Gaussian correlation function. Of specific interest is a maximum likelihood function that decreases...
Efficient quantum algorithm for computing n-time correlation functions.
Pedernales, J S; Di Candia, R; Egusquiza, I L; Casanova, J; Solano, E
2014-07-11
We propose a method for computing n-time correlation functions of arbitrary spinorial, fermionic, and bosonic operators, consisting of an efficient quantum algorithm that encodes these correlations in an initially added ancillary qubit for probe and control tasks. For spinorial and fermionic systems, the reconstruction of arbitrary n-time correlation functions requires the measurement of two ancilla observables, while for bosonic variables time derivatives of the same observables are needed. Finally, we provide examples applicable to different quantum platforms in the frame of the linear response theory.
Correlation of Thyroid Functions with Severity and Outcome of ...
African Journals Online (AJOL)
Background: During normal pregnancy, changes in thyroid function are well documented; however, information regarding thyroid function in preeclampsia is scanty. Aim: The present study was planned to study thyroid hormones in mild and severe preeclamptic women and normotensive women and correlate them with ...
Gluon 2- and 3-Point Correlation Functions on the Lattice
Parrinello, Claudio
1993-01-01
I present some preliminary results, obtained in collaboration with C. Bernard and A. Soni, for the lattice evaluation of 2- and 3-point gluon correlation functions in momentum space, with emphasis on the amputated 3-gluon vertex function. The final goal of this approach is the study of the running QCD coupling constant as defined from the amputated 3-gluon vertex.
2- and 3-point gluon correlation functions on the lattice
Energy Technology Data Exchange (ETDEWEB)
Parrinello, C. (Dept. of Physics, Univ. of Edinburgh (United Kingdom))
1994-04-01
I present some preliminary results, obtained in collaboration with C. Bernard and A. Soni, for the lattice evaluation of 2- and 3-point gluon correlation functions in momentum space, with emphasis on the amputated 3-gluon vertex function. The final goal of this approach is the study of the running QCD coupling constant as defined from the amputated 3-gluon vertex. (orig.)
Current correlation functions of ideal Fermi gas at finite temperature
Indian Academy of Sciences (India)
The diamagnetic susceptibility as a function of temperature has also been obtained from transverse current correlation function as its long wave- length and static limit, which smoothly cross over from known quantum values to the classical limit with increase in temperature. Keywords. Fermi gas; diamagnetic susceptibility; ...
Energy Technology Data Exchange (ETDEWEB)
Matthews, Daniel J.; Newman, Jeffrey A., E-mail: djm70@pitt.edu, E-mail: janewman@pitt.edu [Department of Physics and Astronomy, University of Pittsburgh, 3941 O' Hara Street, Pittsburgh, PA 15260 (United States)
2012-02-01
Cross-correlation techniques provide a promising avenue for calibrating photometric redshifts and determining redshift distributions using spectroscopy which is systematically incomplete (e.g., current deep spectroscopic surveys fail to obtain secure redshifts for 30%-50% or more of the galaxies targeted). In this paper, we improve on the redshift distribution reconstruction methods from our previous work by incorporating full covariance information into our correlation function fits. Correlation function measurements are strongly covariant between angular or spatial bins, and accounting for this in fitting can yield substantial reduction in errors. However, frequently the covariance matrices used in these calculations are determined from a relatively small set (dozens rather than hundreds) of subsamples or mock catalogs, resulting in noisy covariance matrices whose inversion is ill-conditioned and numerically unstable. We present here a method of conditioning the covariance matrix known as ridge regression which results in a more well behaved inversion than other techniques common in large-scale structure studies. We demonstrate that ridge regression significantly improves the determination of correlation function parameters. We then apply these improved techniques to the problem of reconstructing redshift distributions. By incorporating full covariance information, applying ridge regression, and changing the weighting of fields in obtaining average correlation functions, we obtain reductions in the mean redshift distribution reconstruction error of as much as {approx}40% compared to previous methods. We provide a description of POWERFIT, an IDL code for performing power-law fits to correlation functions with ridge regression conditioning that we are making publicly available.
Electron Correlation from the Adiabatic Connection for Multireference Wave Functions
Pernal, Katarzyna
2018-01-01
An adiabatic connection (AC) formula for the electron correlation energy is derived for a broad class of multireference wave functions. The AC expression recovers dynamic correlation energy and assures a balanced treatment of the correlation energy. Coupling the AC formalism with the extended random phase approximation allows one to find the correlation energy only from reference one- and two-electron reduced density matrices. If the generalized valence bond perfect pairing model is employed a simple closed-form expression for the approximate AC formula is obtained. This results in the overall M5 scaling of the computation cost making the method one of the most efficient multireference approaches accounting for dynamic electron correlation also for the strongly correlated systems.
Current correlation functions of ideal Fermi gas at finite temperature
Indian Academy of Sciences (India)
wave vector k. ω and q are the transferred energy and momentum in scattering, respec- tively, and nk =1/(1+e´ ωk µµ kBT ) is the Fermi function with µ and kB as the chemical potential and the Boltzmann constant, respectively. On the other hand, using Green's function theory [14] the transverse current correlation function of ...
Measurement of spatial correlation functions using image processing techniques
International Nuclear Information System (INIS)
Berryman, J.G.
1985-01-01
A procedure for using digital image processing techniques to measure the spatial correlation functions of composite heterogeneous materials is presented. Methods for eliminating undesirable biases and warping in digitized photographs are discussed. Fourier transform methods and array processor techniques for calculating the spatial correlation functions are treated. By introducing a minimal set of lattice-commensurate triangles, a method of sorting and storing the values of three-point correlation functions in a compact one-dimensional array is developed. Examples are presented at each stage of the analysis using synthetic photographs of cross sections of a model random material (the penetrable sphere model) for which the analytical form of the spatial correlations functions is known. Although results depend somewhat on magnification and on relative volume fraction, it is found that photographs digitized with 512 x 512 pixels generally have sufficiently good statistics for most practical purposes. To illustrate the use of the correlation functions, bounds on conductivity for the penetrable sphere model are calculated with a general numerical scheme developed for treating the singular three-dimensional integrals which must be evaluated
Long-time tails of correlation and memory functions
Sawada, Isao
2002-11-01
We review the generalized Langevin equation, which is a transformation and reformulation of equation of motion, from the two viewpoints: the projection operator method developed by Mori and the recurrence relations method developed by Lee. The fluctuating forces acting on the Bloch electrons’ current are clarified the strongly colored quantum fluctuations with the spontaneous interband transitions leading to a long-time tail of 1/ t for the envelope of the memory function. The velocity autocorrelation functions in the coupled harmonic oscillator on the Bethe lattice have a long-time tail of 1/t t. The oscillation and the form of decay found in correlation functions affect transport coefficients given by the integrated intensity up to infinity. We also study the force-force correlation functions often used as an approximation to the memory function.
Correlation between HRCT and pulmonary functional tests in cystic fibrosis
International Nuclear Information System (INIS)
Mastellari, Paola; Biggi, Simona; Lombardi, Alfonsa; Zompatori, Maurizio; Grzincich, Gianluigi; Pisi, Giovanna; Spaggiari, Cinzia
2005-01-01
Purpose. To compare the HRCT score by Oikonottlou and air trapping in expiratory scans with pulmonary functional tests and evaluate which radiological criteria are more useful to predict clinical impairment. Materials and methods. From January to September 2003, pulmonary HRCT study was performed in 37 patients (23 males), aged between 7 and 41 years, with cystic fibrosis. In the same day of CT examination they also received a complete functional evaluation. HRCT studies were evaluated by three radiologists blinded to the clinical data and were correlated with the lung function tests. Results. We obtained a high correlation (p=0.01) for two of the HRCT signs: extent of mucus plugging and mosaic perfusion pattern and all function tests. Discussion. Previous studies have demonstrated good correlation between lung function tests, in particular with FEV1 and HRCT signs. Our study differed from previous ones in that we analysed the correlation between lung function tests and with both single and combined CT criteria. Conclusion. Our results suggest that a simplified HRCT store could be useful to evaluate patients with cystic fibrosis [it
Correlation Functions in Open Quantum-Classical Systems
Directory of Open Access Journals (Sweden)
Chang-Yu Hsieh
2013-12-01
Full Text Available Quantum time correlation functions are often the principal objects of interest in experimental investigations of the dynamics of quantum systems. For instance, transport properties, such as diffusion and reaction rate coefficients, can be obtained by integrating these functions. The evaluation of such correlation functions entails sampling from quantum equilibrium density operators and quantum time evolution of operators. For condensed phase and complex systems, where quantum dynamics is difficult to carry out, approximations must often be made to compute these functions. We present a general scheme for the computation of correlation functions, which preserves the full quantum equilibrium structure of the system and approximates the time evolution with quantum-classical Liouville dynamics. Several aspects of the scheme are discussed, including a practical and general approach to sample the quantum equilibrium density, the properties of the quantum-classical Liouville equation in the context of correlation function computations, simulation schemes for the approximate dynamics and their interpretation and connections to other approximate quantum dynamical methods.
Correlation Function Analysis of Fiber Networks: Implications for Thermal Conductivity
Martinez-Garcia, Jorge; Braginsky, Leonid; Shklover, Valery; Lawson, John W.
2011-01-01
The heat transport in highly porous fiber structures is investigated. The fibers are supposed to be thin, but long, so that the number of the inter-fiber connections along each fiber is large. We show that the effective conductivity of such structures can be found from the correlation length of the two-point correlation function of the local conductivities. Estimation of the parameters, determining the conductivity, from the 2D images of the structures is analyzed.
Dynamic polarization in paramagnetic solids and microscopic correlation functions
International Nuclear Information System (INIS)
Boucher, Jean-Paul
1972-01-01
The different effects of Dynamic Nuclear Polarization in paramagnetic solids are described by means of a single thermodynamic formalism. In the case of large exchange interactions, the Overhauser effect correlated with nuclear relaxation time measurements can provide a way of studying correlation functions between electronic spins. This method is used to study the low-frequency behaviour of the microscopic spectral density which should diverge as ω → 0, in the case of a linear exchange chain. (author) [fr
N=4 superconformal Ward identities for correlation functions
Directory of Open Access Journals (Sweden)
A.V. Belitsky
2016-03-01
Full Text Available In this paper we study the four-point correlation function of the energy–momentum supermultiplet in theories with N=4 superconformal symmetry in four dimensions. We present a compact form of all component correlators as an invariant of a particular abelian subalgebra of the N=4 superconformal algebra. This invariant is unique up to a single function of the conformal cross-ratios which is fixed by comparison with the correlation function of the lowest half-BPS scalar operators. Our analysis is independent of the dynamics of a specific theory, in particular it is valid in N=4 super Yang–Mills theory for any value of the coupling constant. We discuss in great detail a subclass of component correlators, which is a crucial ingredient for the recent study of charge-flow correlations in conformal field theories. We compute the latter explicitly and elucidate the origin of the interesting relations among different types of flow correlations previously observed in arXiv:1309.1424.
Correlation function of null polygonal Wilson loops with local operators
Alday, L. F.; Buchbinder, E. I.; Tseytlin, A. A.
2011-01-01
We consider the correlator of a light-like polygonal Wilson loop with n cusps with a local operator (like the dilaton or the chiral primary scalar) in planar N =4 super Yang-Mills theory. As a consequence of conformal symmetry, the main part of such correlator is a function F of 3n-11 conformal ratios. The first non-trivial case is n=4 when F depends on just one conformal ratio \\zeta. This makes the corresponding correlator one of the simplest non-trivial observables that one would like to c...
Functional correlation approach to operational risk in banking organizations
Kühn, Reimer; Neu, Peter
2003-05-01
A Value-at-Risk-based model is proposed to compute the adequate equity capital necessary to cover potential losses due to operational risks, such as human and system process failures, in banking organizations. Exploring the analogy to a lattice gas model from physics, correlations between sequential failures are modeled by as functionally defined, heterogeneous couplings between mutually supportive processes. In contrast to traditional risk models for market and credit risk, where correlations are described as equal-time-correlations by a covariance matrix, the dynamics of the model shows collective phenomena such as bursts and avalanches of process failures.
Matthews, Daniel J.; Newman, Jeffrey A.
2011-01-01
Cross-correlation techniques provide a promising avenue for calibrating photometric redshifts and determining redshift distributions using spectroscopy which is systematically incomplete (e.g., current deep spectroscopic surveys fail to obtain secure redshifts for 30-50% or more of the galaxies targeted). In this paper we improve on the redshift distribution reconstruction methods presented in Matthews & Newman (2010) by incorporating full covariance information into our correlation function ...
Neutron depolarization in ferromagnets in terms of correlation functions
International Nuclear Information System (INIS)
Valk, H.J.L. van der; Rekveldt, M.T.
1982-01-01
The change of the polarization vector of monochromatic neutron beam after transmitting a ferromagnet can be described by a depolarization matrix. The contributions of different domain structure parameters to the depolarization can be obtained by considering neutron trajectories either passing a number of domains or passing a magnetization distribution described in terms of correlation functions. Both approaches are compared with each other and it is found that they deliver about the same results for ferromagnets composed by small domains. The method of analysing depolarization measurements in terms of domain structure parameters based on correlation functions is useful for ferromagnets close to magnetic saturation. (orig.)
Correlation functions of the spin chains. Algebraic Bethe Ansatz approach
International Nuclear Information System (INIS)
Kitanine, N.
2007-09-01
Spin chains are the basic elements of integrable quantum models. These models have direct applications in condense matter theory, in statistical physics, in quantum optics, in field theory and even in string theory but they are also important because they enable us to solve, in an exact manner, non-perturbative phenomena that otherwise would stay unresolved. The method described in this work is based on the algebraic Bethe Ansatz. It is shown how this method can be used for the computation of null temperature correlation functions of the Heisenberg 1/2 spin chain. The important point of this approach is the solution of the inverse quantum problem given by the XXZ spin chain. This solution as well as a simple formulae for the scalar product of the Bethe states, have enabled us to get the most basic correlation functions under the form of multiple integrals. The formalism of multiple integrals open the way for asymptotic analysis for a few physical quantities like the probability of vacuum formation. It is worth noticing that this formalism can give exact results for two-point functions that are the most important correlation functions for applications. A relationship has been discovered between these multiple integrals and the sum of the form factors. The results have been extended to dynamical correlation functions. (A.C.)
Correlation between thoracolumbar curvatures and respiratory function in older adults
Directory of Open Access Journals (Sweden)
Rahman NNAA
2017-03-01
Full Text Available Nor Najwatul Akmal Ab Rahman,1 Devinder Kaur Ajit Singh,1 Raymond Lee2 1Physiotherapy Programme, School of Rehabilitation Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia; 2School of Applied Sciences, London South Bank University, London, UK Abstract: Aging is associated with alterations in thoracolumbar curvatures and respiratory function. Research information regarding the correlation between thoracolumbar curvatures and a comprehensive examination of respiratory function parameters in older adults is limited. The aim of the present study was to examine the correlation between thoracolumbar curvatures and respiratory function in community-dwelling older adults. Thoracolumbar curvatures (thoracic and lumbar were measured using a motion tracker. Respiratory function parameters such as lung function, respiratory rate, respiratory muscle strength and respiratory muscle thickness (diaphragm and intercostal were measured using a spirometer, triaxial accelerometer, respiratory pressure meter and ultrasound imaging, respectively. Sixty-eight community-dwelling older males and females from Kuala Lumpur, Malaysia, with mean (standard deviation age of 66.63 (5.16 years participated in this cross-sectional study. The results showed that mean (standard deviation thoracic curvature angle and lumbar curvature angles were -46.30° (14.66° and 14.10° (10.58°, respectively. There was a significant negative correlation between thoracic curvature angle and lung function (forced expiratory volume in 1 second: r=-0.23, P<0.05; forced vital capacity: r=-0.32, P<0.05, quiet expiration intercostal thickness (r=-0.22, P<0.05 and deep expiration diaphragm muscle thickness (r=-0.21, P<0.05. The lumbar curvature angle had a significant negative correlation with respiratory muscle strength (r=-0.29, P<0.05 and diaphragm muscle thickness at deep inspiration (r=-0.22, P<0.05. However, respiratory rate
[Structure-function correlation in early diagnosis of glaucoma progression].
Dascălu, Ana-Maria; Alexandrescu, Cristina; Popa-Cherecheanu, Alina; Stana, Daniela; Panca, Aida; Pascu, Ruxandra; Voinea, Liliana
2011-01-01
The study investigates the correlations between structure and function in early detection of glaucoma progression. A prospective study was carried on 204 patients diagnosed with POAG and a follow-up period of 4 years. All the patients underwent complex ophthalmological examination, C/D ratio, Disk Damage Likelyhood Scale (DDLS), automated perimetry and Heidelberg retina tomography The relations between structure and function were investigated for all patients, but also according to clinical stage of glaucomatous damage. Structural progression was more frequently associated with perimetric progression for patients with moderate advanced glaucoma. For patients with preperimetric glaucoma and early glaucoma, the progression was present more often for structural test (19,04% and 29,3%), while perimetric progression was less frequent objectivated and weak correlated with structural progression (16,66%). For the 15 cases diagosed with both structural and functional progression, the locations of the structural lesion and functional defect were better correlated in cases involving the poles of the optic disc. Structure-function relation depends on clinical stage of glaucoma and the location of the glaucomatous defects. In early stages, structural investigations can detect progression before perimetry, while in advanced stages, the functional tests are more useful for early detection of progression.
Correlation between thoracolumbar curvatures and respiratory function in older adults.
Rahman, Nor Najwatul Akmal Ab; Singh, Devinder Kaur Ajit; Lee, Raymond
2017-01-01
Aging is associated with alterations in thoracolumbar curvatures and respiratory function. Research information regarding the correlation between thoracolumbar curvatures and a comprehensive examination of respiratory function parameters in older adults is limited. The aim of the present study was to examine the correlation between thoracolumbar curvatures and respiratory function in community-dwelling older adults. Thoracolumbar curvatures (thoracic and lumbar) were measured using a motion tracker. Respiratory function parameters such as lung function, respiratory rate, respiratory muscle strength and respiratory muscle thickness (diaphragm and intercostal) were measured using a spirometer, triaxial accelerometer, respiratory pressure meter and ultrasound imaging, respectively. Sixty-eight community-dwelling older males and females from Kuala Lumpur, Malaysia, with mean (standard deviation) age of 66.63 (5.16) years participated in this cross-sectional study. The results showed that mean (standard deviation) thoracic curvature angle and lumbar curvature angles were -46.30° (14.66°) and 14.10° (10.58°), respectively. There was a significant negative correlation between thoracic curvature angle and lung function (forced expiratory volume in 1 second: r =-0.23, P <0.05; forced vital capacity: r =-0.32, P <0.05), quiet expiration intercostal thickness ( r =-0.22, P <0.05) and deep expiration diaphragm muscle thickness ( r =-0.21, P <0.05). The lumbar curvature angle had a significant negative correlation with respiratory muscle strength ( r =-0.29, P <0.05) and diaphragm muscle thickness at deep inspiration ( r =-0.22, P <0.05). However, respiratory rate was correlated neither with thoracic nor with lumbar curvatures. The findings of this study suggest that increase in both thoracic and lumbar curvatures is correlated with decrease in respiratory muscle strength, respiratory muscle thickness and some parameters of lung function. Clinically, both thoracic and
Upper Limb Assessment in Tetraplegia: Clinical, Functional and Kinematic Correlations
Cacho, Enio Walker Azevedo; de Oliveira, Roberta; Ortolan, Rodrigo L.; Varoto, Renato; Cliquet, Alberto
2011-01-01
The aim of this study was to correlate clinical and functional evaluations with kinematic variables of upper limp reach-to-grasp movement in patients with tetraplegia. Twenty chronic patients were selected to perform reach-to-grasp kinematic assessment using a target placed at a distance equal to the arm's length. Kinematic variables (hand peak…
The pair correlation function of spatial Hawkes processes
DEFF Research Database (Denmark)
Møller, Jesper; Torrisi, Giovanni Luca
2007-01-01
Spatial Hawkes processes can be considered as spatial versions of classical Hawkes processes. We derive the pair correlation function of stationary spatial Hawkes processes and discuss the connection to the Bartlett spectrum and other summary statistics. Particularly, results for Gaussian fertility...... rates and the extension to spatial Hawkes processes with random fertility rates are discussed....
Statistics of baryon correlation functions in lattice QCD
Wagman, Michael L.; Savage, Martin J.; Nplqcd Collaboration
2017-12-01
A systematic analysis of the structure of single-baryon correlation functions calculated with lattice QCD is performed, with a particular focus on characterizing the structure of the noise associated with quantum fluctuations. The signal-to-noise problem in these correlation functions is shown, as long suspected, to result from a sign problem. The log-magnitude and complex phase are found to be approximately described by normal and wrapped normal distributions respectively. Properties of circular statistics are used to understand the emergence of a large time noise region where standard energy measurements are unreliable. Power-law tails in the distribution of baryon correlation functions, associated with stable distributions and "Lévy flights," are found to play a central role in their time evolution. A new method of analyzing correlation functions is considered for which the signal-to-noise ratio of energy measurements is constant, rather than exponentially degrading, with increasing source-sink separation time. This new method includes an additional systematic uncertainty that can be removed by performing an extrapolation, and the signal-to-noise problem reemerges in the statistics of this extrapolation. It is demonstrated that this new method allows accurate results for the nucleon mass to be extracted from the large-time noise region inaccessible to standard methods. The observations presented here are expected to apply to quantum Monte Carlo calculations more generally. Similar methods to those introduced here may lead to practical improvements in analysis of noisier systems.
Equilibrium time correlation functions in the low density limit
Beijeren, H. van; Lanford, O.E.; Lebowitz, J.L.; Spohn, H.
1980-01-01
We consider a system of hard spheres in thermal equilibrium. Using Lanford's result about the convergence of the solutions of the BBGKY hierarchy to the solutions of the Boltzmann hierarchy, we show that in the low-density limit (Boltzmann-Grad limit): (i) the total time correlation function is
A two-point correlation function for Galactic halo stars
Cooper, A. P.; Cole, S.; Frenk, C. S.; Helmi, A.
2011-01-01
We describe a correlation function statistic that quantifies the amount of spatial and kinematic substructure in the stellar halo. We test this statistic using model stellar halo realizations constructed from the Aquarius suite of six high-resolution cosmological N-body simulations, in combination
Ignoring Functionality as a Correlate of the Underutilization of ...
African Journals Online (AJOL)
Ignoring Functionality as a Correlate of the Underutilization of Computer and Information Technology in Rwandan Higher Education Institutions. ... Data were collected on the institutions' expenditure on components of the TCO and the findings contrasted with documented experiences from CIT-savvy settings, to establish ...
A Correlation of Symptomatology with Lung Function in Patients with ...
African Journals Online (AJOL)
2017-06-28
Jun 28, 2017 ... How to cite this article: Ajiya A, Salisu AD, Nwaorgu O. A correlation of symptomatology with lung function in patients with allergic rhinosinusitis. Niger J Clin Pract 2017;20:647-51. Access this article online. Quick Response Code: Website: www.njcponline.com. DOI: 10.4103/1119-3077.187321. PMID: XXX.
All genus correlation functions for the hermitian 1-matrix model
Eynard, B.
2004-01-01
We rewrite the loop equations of the hermitian matrix model, in a way which allows to compute all the correlation functions, to all orders in the topological $1/N^2$ expansion, as residues on an hyperelliptical curve. Those residues, can be represented diagrammaticaly as Feynmann graphs of a cubic interaction field theory on the curve.
Correlation functions formed by a femtosecond pulse interferometer
Cui, M.; Bhattacharya, N.; Urbach, H.P.; Van den berg, S.A.
2008-01-01
We experimentally demonstrate that a stabilized femtosecond frequency comb can be applied as a tool for distance measurement. The scheme is based on optical interference between individual pulses in a Michelson type interferometer. The cross-correlation functions between individual pulses with a
Correlations and functional connections in a population of grid cells.
Dunn, Benjamin; Mørreaunet, Maria; Roudi, Yasser
2015-02-01
We study the statistics of spike trains of simultaneously recorded grid cells in freely behaving rats. We evaluate pairwise correlations between these cells and, using a maximum entropy kinetic pairwise model (kinetic Ising model), study their functional connectivity. Even when we account for the covariations in firing rates due to overlapping fields, both the pairwise correlations and functional connections decay as a function of the shortest distance between the vertices of the spatial firing pattern of pairs of grid cells, i.e. their phase difference. They take positive values between cells with nearby phases and approach zero or negative values for larger phase differences. We find similar results also when, in addition to correlations due to overlapping fields, we account for correlations due to theta oscillations and head directional inputs. The inferred connections between neurons in the same module and those from different modules can be both negative and positive, with a mean close to zero, but with the strongest inferred connections found between cells of the same module. Taken together, our results suggest that grid cells in the same module do indeed form a local network of interconnected neurons with a functional connectivity that supports a role for attractor dynamics in the generation of grid pattern.
A local dynamic correlation function from inelastic neutron scattering
International Nuclear Information System (INIS)
McQueeney, R.J.
1997-01-01
Information about local and dynamic atomic correlations can be obtained from inelastic neutron scattering measurements by Fourier transform of the Q-dependent intensity oscillations at a particular frequency. A local dynamic structure function, S(r,ω), is defined from the dynamic scattering function, S(Q,ω), such that the elastic and frequency-integrated limits correspond to the average and instantaneous pair-distribution functions, respectively. As an example, S(r,ω) is calculated for polycrystalline aluminum in a model where atomic motions are entirely due to harmonic phonons
Correlation between hypertension and cognitive function in elderly
Fitri, F. I.; Rambe, A. S.
2018-03-01
Hypertension and cognitive impairment are common disorders among elderly adults, and their prevalences tend to rise as the population ages. This study aimed to determine the correlation between hypertension and cognitive function in elderly. It was a cross-sectional study involving 62 elderly subjects. All subjects underwent physical and neurologic examination and Montreal Cognitive Assessment-Indonesian Version (MoCA-INA) to assess cognitive function. This study included 62 subjects consisted of 26 males (41.9%) and 36 females (58.1%). There were 24 subjects (38.2%) with hypertension and 38 (61.3%) normal elderly subjects. The mean age was 65.71±4.49 years old. There were no significant differences in demographic characteristics, total MoCA-INA scores, and scores based on cognitive domains between two groups, except for visuospatial and executive function (p=0.026). There was a significant correlation between hypertension and visuospatial and executive function (r=0.301, p=0.017). Hypertension is correlated with cognitive impairment mainly on visuospatial and executive function in elderly.
Nutritional, functional and psychosocial correlates of disability among older adults.
Johnson, C S J; Mahon, A; McLeod, W
2006-01-01
The purpose of the present study was to examine the nutritional, functional and psychosocial correlates of disability among 54 older adults aged 65 years of age or older. Using validated questionnaires and tests, nutritional risk (Mini-Nutritional Assessment), functional capacity (mobility, balance, endurance, grip strength and lower extremity strength), the psychosocial factors (life satisfaction, depression, and social support) and level of disability of the participants were examined. The study showed that functional mobility was the strongest correlate of disability, even after controlling for age, gender and residential living status (pnutrition risk had marginal significance as being related to disability. The results of the present study have implications for the development of evidence-based health promotion interventions for older adults.
Functional correlates of detailed body composition in healthy elderly subjects.
Geisler, Corinna; Schweitzer, Lisa; Müller, Manfred James
2018-01-01
Methods of body composition analysis are now widely used to characterize health status, i.e., nutritional status, metabolic rates, and cardiometabolic risk factors. However, the functional correlates of individual body components have not been systematically analyzed. In this study, we have used a two-compartment model, which was assessed by air displacement plethysmography. Detailed body composition was measured by whole body magnetic resonance imaging in a healthy population of 40 Caucasians, aged 65-81 yr (20 men; body mass index range: 18.6-37.2 kg/m 2 ). Physical, metabolic, as well as endocrine functions included pulmonary function, handgrip strength, gait speed, sit-to-stand test, physical activity, blood pressure, body temperature, resting energy expenditure (REE), liver and kidney functions (glomerular filtration rate), insulin sensitivity [homeostasis model assessment (HOMA)], plasma lipids, plasma leptin, testosterone, dehydroepiandrosterone, insulin-like growth factor I levels, thyroid status, vitamins, and inflammation. Individual body compartments were intercorrelated, e.g., skeletal muscle mass (SM) correlated with visceral adipose tissue ( r = 0.53) and kidneys ( r = 0.62). For the functional correlates, SM ( r = 0.58) and liver volume ( r = 0.63) were associated with REE, SM correlated with handgrip strength ( r = 0.57), and kidneys with glomerular filtration rate ( r = 0.57). While visceral adipose tissue correlated with HOMA ( r = 0.59), subcutaneous adipose tissue was related to plasma leptin levels ( r = 0.84). The subcutaneous adipose tissue-to-leptin relationship was moderated by inflammation increasing the explained variance of leptin levels by 4.0%. In linear regression analysis, detailed body composition explained variances in REE (75.0%), HOMA (41.0%), and leptin (78.0%) compared with a body mass index-based model (REE 16.0%, HOMA 31.0%, leptin 45.0%). In addition, detailed body composition explained 39
Two-body correlation functions in dilute nuclear matter
International Nuclear Information System (INIS)
Isayev, A A
2006-01-01
Finding the distinct features of the crossover from the regime of large overlapping Cooper pairs to the limit of non-overlapping pairs of fermions (Shafroth pairs) in multicomponent Fermi systems remains one of the actual problems in a quantum many-body theory. Here this transition is studied by calculating the two-body density, spin and isospin correlation functions in dilute asymmetric nuclear matter. It is shown that criterion of the crossover (Phys. Rev. Lett. 95, 090402 (2005)), consisting in the change of the sign of the density correlation function at low momentum transfer, fails to describe correctly the density-driven BEC-BCS transition at finite isospin asymmetry or finite temperature. As an unambiguous signature of the BEC-BCS transition, there can be used the presence (BCS regime) or absence (BEC regime) of the singularity in the momentum distribution of the quasiparticle density of states
Temporal correlation functions of concentration fluctuations: an anomalous case.
Lubelski, Ariel; Klafter, Joseph
2008-10-09
We calculate, within the framework of the continuous time random walk (CTRW) model, multiparticle temporal correlation functions of concentration fluctuations (CCF) in systems that display anomalous subdiffusion. The subdiffusion stems from the nonstationary nature of the CTRW waiting times, which also lead to aging and ergodicity breaking. Due to aging, a system of diffusing particles tends to slow down as time progresses, and therefore, the temporal correlation functions strongly depend on the initial time of measurement. As a consequence, time averages of the CCF differ from ensemble averages, displaying therefore ergodicity breaking. We provide a simple example that demonstrates the difference between these two averages, a difference that might be amenable to experimental tests. We focus on the case of ensemble averaging and assume that the preparation time of the system coincides with the starting time of the measurement. Our analytical calculations are supported by computer simulations based on the CTRW model.
CCFpams: Atmospheric stellar parameters from cross-correlation functions
Malavolta, Luca; Lovis, Christophe; Pepe, Francesco; Sneden, Christopher; Udry, Stephane
2017-07-01
CCFpams allows the measurement of stellar temperature, metallicity and gravity within a few seconds and in a completely automated fashion. Rather than performing comparisons with spectral libraries, the technique is based on the determination of several cross-correlation functions (CCFs) obtained by including spectral features with different sensitivity to the photospheric parameters. Literature stellar parameters of high signal-to-noise (SNR) and high-resolution HARPS spectra of FGK Main Sequence stars are used to calibrate the stellar parameters as a function of CCF areas.
An improved method for estimating the frequency correlation function
Chelli, Ali
2012-04-01
For time-invariant frequency-selective channels, the transfer function is a superposition of waves having different propagation delays and path gains. In order to estimate the frequency correlation function (FCF) of such channels, the frequency averaging technique can be utilized. The obtained FCF can be expressed as a sum of auto-terms (ATs) and cross-terms (CTs). The ATs are caused by the autocorrelation of individual path components. The CTs are due to the cross-correlation of different path components. These CTs have no physical meaning and leads to an estimation error. We propose a new estimation method aiming to improve the estimation accuracy of the FCF of a band-limited transfer function. The basic idea behind the proposed method is to introduce a kernel function aiming to reduce the CT effect, while preserving the ATs. In this way, we can improve the estimation of the FCF. The performance of the proposed method and the frequency averaging technique is analyzed using a synthetically generated transfer function. We show that the proposed method is more accurate than the frequency averaging technique. The accurate estimation of the FCF is crucial for the system design. In fact, we can determine the coherence bandwidth from the FCF. The exact knowledge of the coherence bandwidth is beneficial in both the design as well as optimization of frequency interleaving and pilot arrangement schemes. © 2012 IEEE.
Charmonium correlators and spectral functions at finite temperature
Energy Technology Data Exchange (ETDEWEB)
Ding,H.T.; Kaczmarek, O.; Karsch, F.; Satz, H.
2008-09-01
We present an operational approach to address the in-medium behavior of charmonium and analyze the reliability of maximum entropy method (MEM). We study the dependences of the ratio of correlators to the reconstructed one and the free one on the resonance's width and the continuum's threshold. Furthermore, we discuss the issue of the default model dependence of the spectral function obtained from MEM.
Quantum electrodynamics and light rays. [Two-point correlation functions
Energy Technology Data Exchange (ETDEWEB)
Sudarshan, E.C.G.
1978-11-01
Light is a quantum electrodynamic entity and hence bundles of rays must be describable in this framework. The duality in the description of elementary optical phenomena is demonstrated in terms of two-point correlation functions and in terms of collections of light rays. The generalizations necessary to deal with two-slit interference and diffraction by a rectangular slit are worked out and the usefulness of the notion of rays of darkness illustrated. 10 references.
mTransport: Two-point-correlation function calculator
Dias, Mafalda; Frazer, Jonathan; Seery, David
2017-10-01
mTransport computes the 2-point-correlation function of the curvature and tensor perturbations in multifield models of inflation in the presence of a curved field space. It is a Mathematica implementation of the transport method which encompasses scenarios with violations of slow-roll conditions and turns of the trajectory in field space. It can be used for an arbitrary mass spectrum, including massive modes, particle production and models with quasi-single-field dynamics.
Total Correlation Function Integrals and Isothermal Compressibilities from Molecular Simulations
DEFF Research Database (Denmark)
Wedberg, Rasmus; Peters, Günther H.j.; Abildskov, Jens
2008-01-01
Generation of thermodynamic data, here compressed liquid density and isothermal compressibility data, using molecular dynamics simulations is investigated. Five normal alkane systems are simulated at three different state points. We compare two main approaches to isothermal compressibilities: (1......) fluctuation solution theory analysis of trajectories obtained from simulations to yield total correlation function integrals; and (2) the more commonly used fluctuation formula. The results show that the two approaches yield consistent values and consistent uncertainties. Also, the computations converge...
Voronoi Tessellation for reducing the processing time of correlation functions
Cárdenas-Montes, Miguel; Sevilla-Noarbe, Ignacio
2018-01-01
The increase of data volume in Cosmology is motivating the search of new solutions for solving the difficulties associated with the large processing time and precision of calculations. This is specially true in the case of several relevant statistics of the galaxy distribution of the Large Scale Structure of the Universe, namely the two and three point angular correlation functions. For these, the processing time has critically grown with the increase of the size of the data sample. Beyond parallel implementations to overcome the barrier of processing time, space partitioning algorithms are necessary to reduce the computational load. These can delimit the elements involved in the correlation function estimation to those that can potentially contribute to the final result. In this work, Voronoi Tessellation is used to reduce the processing time of the two-point and three-point angular correlation functions. The results of this proof-of-concept show a significant reduction of the processing time when preprocessing the galaxy positions with Voronoi Tessellation.
Trait correlates and functional significance of heteranthery in flowering plants.
Vallejo-Marín, Mario; Da Silva, Elizabeth M; Sargent, Risa D; Barrett, Spencer C H
2010-10-01
• Flowering plants display extraordinary diversity in the morphology of male sexual organs, yet the functional significance of this variation is not well understood. Here, we conducted a comparative analysis of floral correlates of heteranthery - the morphological and functional differentiation of anthers within flowers - among angiosperm families to identify traits associated with this condition. • We performed a phylogenetic analysis of correlated evolution between heteranthery and several floral traits commonly reported from heterantherous taxa. In addition, we quantified the effect of phylogenetic uncertainty in the observed patterns of correlated evolution by comparing trees in which polytomous branches were randomly resolved. • Heteranthery is reported from 12 angiosperm orders and is phylogenetically associated with the absence of floral nectaries, buzz-pollination and enantiostyly (mirror-image flowers). These associations are robust to particularities of the underlying phylogenetic hypothesis. • Heteranthery has probably evolved as a result of pollinator-mediated selection and appears to function to reduce the conflict of relying on pollen both as food to attract pollinators and as the agent of male gamete transfer. The relative scarcity of heteranthery among angiosperm families suggests that the conditions permitting its evolution are not easily met despite the abundance of pollen-collecting bees and nectarless flowers. © The Authors (2010). Journal compilation © New Phytologist Trust (2010).
Correlates of cognitive function scores in elderly outpatients.
Mangione, C M; Seddon, J M; Cook, E F; Krug, J H; Sahagian, C R; Campion, E W; Glynn, R J
1993-05-01
To determine medical, ophthalmologic, and demographic predictors of cognitive function scores as measured by the Telephone Interview for Cognitive Status (TICS), an adaptation of the Folstein Mini-Mental Status Exam. A secondary objective was to perform an item-by-item analysis of the TICS scores to determine which items correlated most highly with the overall scores. Cross-sectional cohort study. The Glaucoma Consultation Service of the Massachusetts Eye and Ear Infirmary. 472 of 565 consecutive patients age 65 and older who were seen at the Glaucoma Consultation Service between November 1, 1987 and October 31, 1988. Each subject had a standard visual examination and review of medical history at entry, followed by a telephone interview that collected information on demographic characteristics, cognitive status, health status, accidents, falls, symptoms of depression, and alcohol intake. A multivariate linear regression model of correlates of TICS score found the strongest correlates to be education, age, occupation, and the presence of depressive symptoms. The only significant ocular condition that correlated with lower TICS score was the presence of surgical aphakia (model R2 = .46). Forty-six percent (216/472) of patients fell below the established definition of normal on the mental status scale. In a logistic regression analysis, the strongest correlates of an abnormal cognitive function score were age, diabetes, educational status, and occupational status. An item analysis using step-wise linear regression showed that 85 percent of the variance in the TICS score was explained by the ability to perform serial sevens and to repeat 10 items immediately after hearing them. Educational status correlated most highly with both of these items (Kendall Tau R = .43 and Kendall Tau R = .30, respectively). Education, occupation, depression, and age were the strongest correlates of the score on this new screening test for assessing cognitive status. These factors were
Structural and functional neural correlates of music perception.
Limb, Charles J
2006-04-01
This review article highlights state-of-the-art functional neuroimaging studies and demonstrates the novel use of music as a tool for the study of human auditory brain structure and function. Music is a unique auditory stimulus with properties that make it a compelling tool with which to study both human behavior and, more specifically, the neural elements involved in the processing of sound. Functional neuroimaging techniques represent a modern and powerful method of investigation into neural structure and functional correlates in the living organism. These methods have demonstrated a close relationship between the neural processing of music and language, both syntactically and semantically. Greater neural activity and increased volume of gray matter in Heschl's gyrus has been associated with musical aptitude. Activation of Broca's area, a region traditionally considered to subserve language, is important in interpreting whether a note is on or off key. The planum temporale shows asymmetries that are associated with the phenomenon of perfect pitch. Functional imaging studies have also demonstrated activation of primitive emotional centers such as ventral striatum, midbrain, amygdala, orbitofrontal cortex, and ventral medial prefrontal cortex in listeners of moving musical passages. In addition, studies of melody and rhythm perception have elucidated mechanisms of hemispheric specialization. These studies show the power of music and functional neuroimaging to provide singularly useful tools for the study of brain structure and function.
Fast methods for spatially correlated multilevel functional data
Staicu, A.-M.
2010-01-19
We propose a new methodological framework for the analysis of hierarchical functional data when the functions at the lowest level of the hierarchy are correlated. For small data sets, our methodology leads to a computational algorithm that is orders of magnitude more efficient than its closest competitor (seconds versus hours). For large data sets, our algorithm remains fast and has no current competitors. Thus, in contrast to published methods, we can now conduct routine simulations, leave-one-out analyses, and nonparametric bootstrap sampling. Our methods are inspired by and applied to data obtained from a state-of-the-art colon carcinogenesis scientific experiment. However, our models are general and will be relevant to many new data sets where the object of inference are functions or images that remain dependent even after conditioning on the subject on which they are measured. Supplementary materials are available at Biostatistics online.
Reduced density-matrix functional theory: Correlation and spectroscopy.
Di Sabatino, S; Berger, J A; Reining, L; Romaniello, P
2015-07-14
In this work, we explore the performance of approximations to electron correlation in reduced density-matrix functional theory (RDMFT) and of approximations to the observables calculated within this theory. Our analysis focuses on the calculation of total energies, occupation numbers, removal/addition energies, and spectral functions. We use the exactly solvable Hubbard dimer at 1/4 and 1/2 fillings as test systems. This allows us to analyze the underlying physics and to elucidate the origin of the observed trends. For comparison, we also report the results of the GW approximation, where the self-energy functional is approximated, but no further hypothesis is made concerning the approximations of the observables. In particular, we focus on the atomic limit, where the two sites of the dimer are pulled apart and electrons localize on either site with equal probability, unless a small perturbation is present: this is the regime of strong electron correlation. In this limit, using the Hubbard dimer at 1/2 filling with or without a spin-symmetry-broken ground state allows us to explore how degeneracies and spin-symmetry breaking are treated in RDMFT. We find that, within the used approximations, neither in RDMFT nor in GW, the signature of strong correlation is present, when looking at the removal/addition energies and spectral function from the spin-singlet ground state, whereas both give the exact result for the spin-symmetry broken case. Moreover, we show how the spectroscopic properties change from one spin structure to the other.
Reduced density-matrix functional theory: Correlation and spectroscopy
Energy Technology Data Exchange (ETDEWEB)
Di Sabatino, S.; Romaniello, P. [Laboratoire de Physique Théorique, CNRS, IRSAMC, Université Toulouse III–Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex, France and ETSF (France); Berger, J. A. [Laboratoire de Chimie et Physique Quantiques, IRSAMC, Université Toulouse III–Paul Sabatier, CNRS, 118 Route de Narbonne, 31062 Toulouse Cedex, France and ETSF (France); Reining, L. [Laboratoire des Solides Irradiés, École Polytechnique, CNRS, CEA-DSM, 91128 Palaiseau, France and ETSF (France)
2015-07-14
In this work, we explore the performance of approximations to electron correlation in reduced density-matrix functional theory (RDMFT) and of approximations to the observables calculated within this theory. Our analysis focuses on the calculation of total energies, occupation numbers, removal/addition energies, and spectral functions. We use the exactly solvable Hubbard dimer at 1/4 and 1/2 fillings as test systems. This allows us to analyze the underlying physics and to elucidate the origin of the observed trends. For comparison, we also report the results of the GW approximation, where the self-energy functional is approximated, but no further hypothesis is made concerning the approximations of the observables. In particular, we focus on the atomic limit, where the two sites of the dimer are pulled apart and electrons localize on either site with equal probability, unless a small perturbation is present: this is the regime of strong electron correlation. In this limit, using the Hubbard dimer at 1/2 filling with or without a spin-symmetry-broken ground state allows us to explore how degeneracies and spin-symmetry breaking are treated in RDMFT. We find that, within the used approximations, neither in RDMFT nor in GW, the signature of strong correlation is present, when looking at the removal/addition energies and spectral function from the spin-singlet ground state, whereas both give the exact result for the spin-symmetry broken case. Moreover, we show how the spectroscopic properties change from one spin structure to the other.
Approximate models for the analysis of laser velocimetry correlation functions
International Nuclear Information System (INIS)
Robinson, D.P.
1981-01-01
Velocity distributions in the subchannels of an eleven pin test section representing a slice through a Fast Reactor sub-assembly were measured with a dual beam laser velocimeter system using a Malvern K 7023 digital photon correlator for signal processing. Two techniques were used for data reduction of the correlation function to obtain velocity and turbulence values. Whilst both techniques were in excellent agreement on the velocity, marked discrepancies were apparent in the turbulence levels. As a consequence of this the turbulence data were not reported. Subsequent investigation has shown that the approximate technique used as the basis of Malvern's Data Processor 7023V is restricted in its range of application. In this note alternative approximate models are described and evaluated. The objective of this investigation was to develop an approximate model which could be used for on-line determination of the turbulence level. (author)
The ion-electron correlation function in liquid metals
International Nuclear Information System (INIS)
Takeda, S.; Tamaki, S.; Waseda, Y.
1985-01-01
The structure factors of liquid Zn at 723 K, Sn at 523 K and Bi at 573 K have been determined by neutron diffraction with sufficient accuracy and compared with those of X-ray diffraction. A remarkable difference in the structural information between the two methods is clearly found around the first peak region as well as in the slightly varied peak positions, and it is apparently larger than the experimental errors. With these facts in mind, a new method evaluating the ion-electron correlation function in liquid metals has been proposed by using the measured structural data of X-rays and neutrons, with the help of theoretical values of the electron-electron correlation function by he Utsumi-Ichimaru scheme. This method has been applied to liquid Zn, Sn and Bi, and the radial distribution function of valence electrons around an ion has been estimated, from which the ionic radius and the schematic diagram of the electron distribution map are obtained. The ionic radii evaluated in this work have been found to agree well with those proposed by Pauling. (author)
Magnetocompositonal correlation function for FeV13.5%
International Nuclear Information System (INIS)
Robinson, D.J.; Hicks, T.J.
2000-01-01
Full text: Many properties of alloys are dependent upon the type of atomic order present and as such, for future development of metallic alloys, it is imperative that an intricate understanding of the ordering processes is obtained. Of particular importance for the transition metal series is the presence of localised magnetic moments which can have a profound effect on the electronic structure, and hence the types of atomic order observed. A first principles ab initio theory has been developed which incorporates these localised moments, and leads to the determination of correlation functions which indicate the type of short-range order present in the high temperature disordered state. The magnetocompositional correlation function, which measures the local magnetic moments dependence on the local atomic environment, has been calculated for an FeV13.5% crystal below the ferromagnetic ordering temperature. This function is observable using polarised neutron scattering allowing a determination of the validity of the theory. Recently obtained results for a single FeV13.5% crystal will be presented for comparison
Finite-temperature correlation functions of Heisenberg antiferromagnet
International Nuclear Information System (INIS)
Izergin, A.G.; Korepin, V.E.; Slavnov, N.A.
1988-01-01
The finite-temperature correlation functions in the one-dimensional Heisenberg XXZ magnet are investigated in the framework of the quantum inverse scattering method. On the transition to nonzero temperatures, it is necessary in this case to solve a number of basically new problems. The main one of these is related to the fact that the ground state of the Hamiltonian (physical vacuum) at nonzero temperature (more precisely, the state of thermodynamic equilibrium) includes many species of particles - not only elementary particles but also bound states of them. We give an appropriate generalization of the method
Summability of Connected Correlation Functions of Coupled Lattice Fields
Lukkarinen, Jani; Marcozzi, Matteo; Nota, Alessia
2018-03-01
We consider two nonindependent random fields ψ and φ defined on a countable set Z. For instance, Z=Z^d or Z=Z^d× I , where I denotes a finite set of possible "internal degrees of freedom" such as spin. We prove that, if the cumulants of ψ and φ enjoy a certain decay property, then all joint cumulants between ψ and φ are ℓ_2 -summable in the precise sense described in the text. The decay assumption for the cumulants of ψ and φ is a restricted ℓ_1 summability condition called ℓ_1 -clustering property. One immediate application of the results is given by a stochastic process ψ _t(x) whose state is ℓ_1 -clustering at any time t: then the above estimates can be applied with ψ =ψ _t and φ =ψ _0 and we obtain uniform in t estimates for the summability of time-correlations of the field. The above clustering assumption is obviously satisfied by any ℓ_1 -clustering stationary state of the process, and our original motivation for the control of the summability of time-correlations comes from a quest for a rigorous control of the Green-Kubo correlation function in such a system. A key role in the proof is played by the properties of non-Gaussian Wick polynomials and their connection to cumulants
Pair correlation functions of strongly coupled two-temperature plasma
Shaffer, Nathaniel R.; Tiwari, Sanat Kumar; Baalrud, Scott D.
2017-09-01
Using molecular dynamics simulations, we perform the first direct tests of three proposed models for the pair correlation functions of strongly coupled plasmas with species of unequal temperature. The models are all extensions of the Ornstein-Zernike/hypernetted-chain theory used to good success for equilibrium plasmas. Each theory is evaluated at several coupling strengths, temperature ratios, and mass ratios for a model plasma in which the electrons are positively charged. We show that the model proposed by Seuferling et al. [Phys. Rev. A 40, 323 (1989)] agrees well with molecular dynamics over a wide range of mass and temperature ratios, as well as over a range of coupling strength similar to that of the equilibrium hypernetted-chain (HNC) theory. The SVT model also correctly predicts the strength of interspecies correlations and exhibits physically reasonable long-wavelength limits of the static structure factors. Comparisons of the SVT model with the Yukawa one-component plasma (YOCP) model are used to show that ion-ion pair correlations are well described by the YOCP model up to Γe≈1 , beyond which it rapidly breaks down.
Pulmonary alveolar proteinosis: Quantitative CT and pulmonary functional correlations
Energy Technology Data Exchange (ETDEWEB)
Guan, Yubao, E-mail: yubaoguan@163.com [Department of Radiology, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120 (China); State Key Laboratory of Respiratory Disease, Guangzhou 510120 (China); Zeng, Qingsi [Department of Radiology, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120 (China); Yang, Haihong; Zheng, Jinping; Li, Shiyue; Gao, Yi [State Key Laboratory of Respiratory Disease, Guangzhou 510120 (China); Deng, Yu [Department of Radiology, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120 (China); Mei, Jiang [State Key Laboratory of Respiratory Disease, Guangzhou 510120 (China); He, Jianxing, E-mail: jianxing63@163.com [State Key Laboratory of Respiratory Disease, Guangzhou 510120 (China); Zhong, Nanshan, E-mail: nanshan@vip.163.com [State Key Laboratory of Respiratory Disease, Guangzhou 510120 (China)
2012-09-15
Objective: We assessed the relationship between quantitative computer tomography (qCT) and the pulmonary function test (PFT) or blood gas analysis in pulmonary alveolar proteinosis (PAP) patients, as well as the utility of these analyses to monitor responses to whole lung lavage (WLL) therapy. Methods: Thirty-eight PAP patients simultaneously received a CT scan and PFT. Fifteen of these patients, undergoing sequential WLL for a total of 20 lavages, also underwent chest CT scans and blood gas analysis before and after WLL, and 14 of 15 patients underwent simultaneous PFT analysis. Differences between the qCT and PFT results were analyzed by canonical correlation. Results: PAP patients with low predicted values for FVC, FEV1, D{sub LCO} and D{sub LCO}/VA indicated small airspace volume and mean lung inflation, low airspace volume/total lung volume ratio and high mean lung density. Correlation and regression analysis revealed a strong correlation between D{sub LCO} and PaO{sub 2} values with CT results. The qCT results indicated that WLL significantly decreased lung weights and mean lung densities, and improved the total airspace volume/total lung volume ratios and mean lung inflations. Conclusion: Quantitative CT may be a sensitive tool for measuring the response of PAP patients to medical interventions such as WLL.
On form factors and correlation functions in twistor space
Energy Technology Data Exchange (ETDEWEB)
Koster, Laura [Institut für Mathematik, Institut für Physik und IRIS Adlershof,Humboldt-Universität zu Berlin,Zum Großen Windkanal 6, 12489 Berlin (Germany); Mitev, Vladimir [PRISMA Cluster of Excellence, Institut für Physik, WA THEP,Johannes Gutenberg-Universität Mainz,Staudingerweg 7, 55128 Mainz (Germany); Staudacher, Matthias [Institut für Mathematik, Institut für Physik und IRIS Adlershof,Humboldt-Universität zu Berlin,Zum Großen Windkanal 6, 12489 Berlin (Germany); Wilhelm, Matthias [Niels Bohr Institute, Copenhagen University,Blegdamsvej 17, 2100 Copenhagen Ø (Denmark)
2017-03-24
In this paper, we continue our study of form factors and correlation functions of gauge-invariant local composite operators in the twistor-space formulation of N=4 super Yang-Mills theory. Using the vertices for these operators obtained in our recent papers (DOI: 10.1103/PhysRevLett.117.011601; 10.1007/JHEP06(2016)162 ), we show how to calculate the twistor-space diagrams for general N{sup k}MHV form factors via the inverse soft limit, in analogy to the amplitude case. For general operators without α-dot indices, we then reexpress the NMHV form factors from the position-twistor calculation in terms of momentum twistors, deriving and expanding on a relation between the two twistor formalisms previously observed in the case of amplitudes. Furthermore, we discuss the calculation of generalized form factors and correlation functions as well as the extension to loop level, in particular providing an argument promised in https://www.doi.org/10.1002/prop.201400085.
Omega from the anisotropy of the redshift correlation function
Hamilton, A. J. S.
1993-01-01
Peculiar velocities distort the correlation function of galaxies observed in redshift space. In the large scale, linear regime, the distortion takes a characteristic quadrupole plus hexadecapole form, with the amplitude of the distortion depending on the cosmological density parameter omega. Preliminary measurements are reported here of the harmonics of the correlation function in the CfA, SSRS, and IRAS 2 Jansky redshift surveys. The observed behavior of the harmonics agrees qualitatively with the predictions of linear theory on large scales in every survey. However, real anisotropy in the galaxy distribution induces large fluctuations in samples which do not yet probe a sufficiently fair volume of the Universe. In the CfA 14.5 sample in particular, the Great Wall induces a large negative quadrupole, which taken at face value implies an unrealistically large omega 20. The IRAS 2 Jy survey, which covers a substantially larger volume than the optical surveys and is less affected by fingers-of-god, yields a more reliable and believable value, omega = 0.5 sup +.5 sub -.25.
On form factors and correlation functions in twistor space
International Nuclear Information System (INIS)
Koster, Laura; Mitev, Vladimir; Staudacher, Matthias; Wilhelm, Matthias
2017-01-01
In this paper, we continue our study of form factors and correlation functions of gauge-invariant local composite operators in the twistor-space formulation of N=4 super Yang-Mills theory. Using the vertices for these operators obtained in our recent papers (DOI: 10.1103/PhysRevLett.117.011601; 10.1007/JHEP06(2016)162 ), we show how to calculate the twistor-space diagrams for general N k MHV form factors via the inverse soft limit, in analogy to the amplitude case. For general operators without α-dot indices, we then reexpress the NMHV form factors from the position-twistor calculation in terms of momentum twistors, deriving and expanding on a relation between the two twistor formalisms previously observed in the case of amplitudes. Furthermore, we discuss the calculation of generalized form factors and correlation functions as well as the extension to loop level, in particular providing an argument promised in https://www.doi.org/10.1002/prop.201400085.
Correlating Function and Imaging Measures of the Medial Longitudinal Fasciculus.
Directory of Open Access Journals (Sweden)
Ken Sakaie
Full Text Available To test the validity of diffusion tensor imaging (DTI measures of tissue injury by examining such measures in a white matter structure with well-defined function, the medial longitudinal fasciculus (MLF. Injury to the MLF underlies internuclear ophthalmoparesis (INO.40 MS patients with chronic INO and 15 healthy controls were examined under an IRB-approved protocol. Tissue integrity of the MLF was characterized by DTI parameters: longitudinal diffusivity (LD, transverse diffusivity (TD, mean diffusivity (MD and fractional anisotropy (FA. Severity of INO was quantified by infrared oculography to measure versional disconjugacy index (VDI.LD was significantly lower in patients than in controls in the medulla-pons region of the MLF (p < 0.03. FA was also lower in patients in the same region (p < 0.0004. LD of the medulla-pons region correlated with VDI (R = -0.28, p < 0.05 as did FA in the midbrain section (R = 0.31, p < 0.02.This study demonstrates that DTI measures of brain tissue injury can detect injury to a functionally relevant white matter pathway, and that such measures correlate with clinically accepted evaluation indices for INO. The results validate DTI as a useful imaging measure of tissue integrity.
International Nuclear Information System (INIS)
Feng Weiguo; Wang Hongwei; Wu Xiang
1989-12-01
Based on the real space Correlated-Basis-Functions theory and the collective oscillation behaviour of the electron gas with effective Coulomb interaction, the many body wave function is obtained for the quasi-two-dimensional electron system in the semiconductor inversion layer. The pair-correlation function and the correlation energy of the system have been calculated by the integro-differential method in this paper. The comparison with the other previous theoretical results is also made. The new theoretical approach and its numerical results show that the pair-correlation functions are definitely positive and satisfy the normalization condition. (author). 10 refs, 2 figs
Correlation functions from a unified variational principle: Trial Lie groups
Energy Technology Data Exchange (ETDEWEB)
Balian, R., E-mail: roger.balian@cea.fr [Institut de Physique Théorique, CEA Saclay, 91191 Gif-sur-Yvette cedex (France); Vénéroni, M. [Institut de Physique Nucléaire, Université Paris-Sud and IN2P3-CNRS, F-91406 Orsay cedex (France)
2015-11-15
Time-dependent expectation values and correlation functions for many-body quantum systems are evaluated by means of a unified variational principle. It optimizes a generating functional depending on sources associated with the observables of interest. It is built by imposing through Lagrange multipliers constraints that account for the initial state (at equilibrium or off equilibrium) and for the backward Heisenberg evolution of the observables. The trial objects are respectively akin to a density operator and to an operator involving the observables of interest and the sources. We work out here the case where trial spaces constitute Lie groups. This choice reduces the original degrees of freedom to those of the underlying Lie algebra, consisting of simple observables; the resulting objects are labeled by the indices of a basis of this algebra. Explicit results are obtained by expanding in powers of the sources. Zeroth and first orders provide thermodynamic quantities and expectation values in the form of mean-field approximations, with dynamical equations having a classical Lie–Poisson structure. At second order, the variational expression for two-time correlation functions separates–as does its exact counterpart–the approximate dynamics of the observables from the approximate correlations in the initial state. Two building blocks are involved: (i) a commutation matrix which stems from the structure constants of the Lie algebra; and (ii) the second-derivative matrix of a free-energy function. The diagonalization of both matrices, required for practical calculations, is worked out, in a way analogous to the standard RPA. The ensuing structure of the variational formulae is the same as for a system of non-interacting bosons (or of harmonic oscillators) plus, at non-zero temperature, classical Gaussian variables. This property is explained by mapping the original Lie algebra onto a simpler Lie algebra. The results, valid for any trial Lie group, fulfill
Correlations between respiratory and functional variables in heart failure
Directory of Open Access Journals (Sweden)
FÃ¡bio Cangeri Di Naso
2009-09-01
Full Text Available Background: Respiratory alterations can impact on the functional performance of patients with heart failure. Aim: To correlate maximum inspiratory muscular force and lung function variables with functional capacity in heart failure patients. Methods: A transversal study January-July 2007 with 42 chronic heart disease patients (28 males with no prior pulmonary illness. The patients were in New York Heart Association Functional Class I, II and III. The variables used were maximum inspiratory pressure, forced vital capacity and forced expiratory volume in the first second. Respiratory variables measured were distance covered in the six-minute walk test, NYHA functional class and the physical functioning domain of the Short Form-36 Quality of Life Questionnaire. Results: Maximum inspiratory pressure correlated with the six-minute walk test (rÂ =Â 0.543 and pÂ <Â 0.001, functional capacity (rÂ =Â â0.566 and pÂ <Â 0.001 and the physical functioning domain score of the Short Form-36 (rÂ =Â 0.459 and pÂ =Â 0.002. The same was true of forced vital capacity and the six-minute walk test (rÂ =Â 0.501 and pÂ =Â 0.001, functional capacity (rÂ =Â â0.477 and pÂ =Â 0.001 and Short Form-36 (rÂ =Â 0.314 and pÂ =Â 0.043 variables. Forced expiratory volume correlated with the distance covered in the six-minute walk test (rÂ =Â 0.514 and pÂ <Â 0.001 and functional capacity (rÂ =Â â0.383 and pÂ =Â 0.012. Conclusion: Lung function and inspiratory muscular force respiratory variables correlated with functional variables in patients with heart failure. Resumo: Fundamento: AlteraÃ§Ãµes respiratÃ³rias podem influenciar o desempenho funcional em doentes com insuficiÃªncia cardÃaca (IC. Objectivo: Correlacionar a forÃ§a muscular inspiratÃ³ria mÃ¡xima (PImax e as variÃ¡veis da funÃ§Ã£o pulmonar com a capacidade funcional em doentes com IC. MÃ©todos: Estudo transversal
Singular value correlation functions for products of Wishart random matrices
International Nuclear Information System (INIS)
Akemann, Gernot; Kieburg, Mario; Wei, Lu
2013-01-01
We consider the product of M quadratic random matrices with complex elements and no further symmetry, where all matrix elements of each factor have a Gaussian distribution. This generalizes the classical Wishart–Laguerre Gaussian unitary ensemble with M = 1. In this paper, we first compute the joint probability distribution for the singular values of the product matrix when the matrix size N and the number M are fixed but arbitrary. This leads to a determinantal point process which can be realized in two different ways. First, it can be written as a one-matrix singular value model with a non-standard Jacobian, or second, for M ⩾ 2, as a two-matrix singular value model with a set of auxiliary singular values and a weight proportional to the Meijer G-function. For both formulations, we determine all singular value correlation functions in terms of the kernels of biorthogonal polynomials which we explicitly construct. They are given in terms of the hypergeometric and Meijer G-functions, generalizing the Laguerre polynomials for M = 1. Our investigation was motivated from applications in telecommunication of multi-layered scattering multiple-input and multiple-output channels. We present the ergodic mutual information for finite-N for such a channel model with M − 1 layers of scatterers as an example. (paper)
Response and correlation functions of nonlinear systems in equilibrium states
Xu, Lubo; Wang, Lei
2017-11-01
In this paper, we study systematically a serial of correlation functions in some one-dimensional nonlinear lattices. Due to the energy conservation law, they are implicitly interdependent. Various transport coefficients are thus also connected. In the studies of the autocorrelations of local energy density and of local heat current, a general relation between diverging heat conduction and super heat diffusion has been proposed recently. We clarify that such a relation is valid only in systems without temperature pressure. In those with temperature pressure, a constant but nontrivial term appears. This term explains a previously observed fact that heat diffusion in such systems is always ballistic but heat conduction can diverge very slowly. Such a result not only disproves the existence of any general relation between diverging heat conduction and super heat diffusion, but it also breaks the long-term presumption that ballistic heat conduction and diffusion always coexist.
Functional Cortical Network in Alpha Band Correlates with Social Bargaining
Billeke, Pablo; Zamorano, Francisco; Chavez, Mario; Cosmelli, Diego; Aboitiz, Francisco
2014-01-01
Solving demanding tasks requires fast and flexible coordination among different brain areas. Everyday examples of this are the social dilemmas in which goals tend to clash, requiring one to weigh alternative courses of action in limited time. In spite of this fact, there are few studies that directly address the dynamics of flexible brain network integration during social interaction. To study the preceding, we carried out EEG recordings while subjects played a repeated version of the Ultimatum Game in both human (social) and computer (non-social) conditions. We found phase synchrony (inter-site-phase-clustering) modulation in alpha band that was specific to the human condition and independent of power modulation. The strength and patterns of the inter-site-phase-clustering of the cortical networks were also modulated, and these modulations were mainly in frontal and parietal regions. Moreover, changes in the individuals’ alpha network structure correlated with the risk of the offers made only in social conditions. This correlation was independent of changes in power and inter-site-phase-clustering strength. Our results indicate that, when subjects believe they are participating in a social interaction, a specific modulation of functional cortical networks in alpha band takes place, suggesting that phase synchrony of alpha oscillations could serve as a mechanism by which different brain areas flexibly interact in order to adapt ongoing behavior in socially demanding contexts. PMID:25286240
Functional neural correlates of social approval in schizophrenia.
Makowski, Carolina S; Lepage, Martin; Harvey, Philippe-Olivier
2016-03-01
Social approval is a reward that uses abstract social reinforcers to guide interpersonal interactions. Few studies have specifically explored social reward processing and its related neural substrates in schizophrenia. Fifteen patients with schizophrenia and fifteen healthy controls participated in a two-part study to explore the functional neural correlates of social approval. In the first session, participants were led to believe their personality would be assessed based on their results from various questionnaires and an interview. Participants were then presented with the results of their supposed evaluation in the scanner, while engaging in a relevant fMRI social approval task. Subjects provided subjective reports of pleasure associated with receiving self-directed positive or negative feedback. Higher activation of the right parietal lobe was found in controls compared with individuals with schizophrenia. Both groups rated traits from the high social reward condition as more pleasurable than the low social reward condition, while intergroup differences emerged in the low social reward condition. Positive correlations were found in patients only between subjective ratings of positive feedback and right insula activation, and a relevant behavioural measure. Evidence suggests potential neural substrates underlying the cognitive representation of social reputation in schizophrenia. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.
Correlation functions and susceptibilities of photonics band gap reservoirs
International Nuclear Information System (INIS)
Konopka, M.
1998-01-01
We investigate quantum statistical properties of photonic band gap reservoirs in terms of correlation functions and susceptibilities in time and spectral domains. Typical features are oscillations of the time-dependent correlation functions and susceptibilities. This is because photonic bad gap reservoirs are intrinsically non-Markovian reservoirs. The results help us to understand better how intrinsic quantum-statistical properties of a reservoir influence dynamics of an atom interacting with this reservoir. Boundary conditions influence time and spectral properties of the electromagnetic field. This well-known fact has a great importance in optics and generally in electromagnetism. Specific examples are resonators used in laser technique and cavity electrodynamics. In quantum optics high-Q micro cavities are used for single-atom experiments when an atom can interact in a coherent way with an electromagnetic field which has its mode structure totally different from those in free space. In particular, interaction of an (effectively) two-level atom with a single-mode cavity field was observed in the region of microwaves (with the wavelength about 1 cm). In 1987 Yablonovitch and John independently proposed that certain periodic dielectric structures can present forbidden frequency gaps (or pseudo gaps in partially disordered structures) for transverse modes. Such periodic structures were named 'photonic band structures' or 'photonic crystals', in analogy with electronic crystals which also have a (forbidden) gap for electronic energy. For true photonic crystals the basic property of blocking electromagnetic wave propagation must be fulfilled for all waves within some frequency range, i.e. for all wavevector and polarization directions
Elucidation of spin echo small angle neutron scattering correlation functions through model studies.
Shew, Chwen-Yang; Chen, Wei-Ren
2012-02-14
Several single-modal Debye correlation functions to approximate part of the overall Debey correlation function of liquids are closely examined for elucidating their behavior in the corresponding spin echo small angle neutron scattering (SESANS) correlation functions. We find that the maximum length scale of a Debye correlation function is identical to that of its SESANS correlation function. For discrete Debye correlation functions, the peak of SESANS correlation function emerges at their first discrete point, whereas for continuous Debye correlation functions with greater width, the peak position shifts to a greater value. In both cases, the intensity and shape of the peak of the SESANS correlation function are determined by the width of the Debye correlation functions. Furthermore, we mimic the intramolecular and intermolecular Debye correlation functions of liquids composed of interacting particles based on a simple model to elucidate their competition in the SESANS correlation function. Our calculations show that the first local minimum of a SESANS correlation function can be negative and positive. By adjusting the spatial distribution of the intermolecular Debye function in the model, the calculated SESANS spectra exhibit the profile consistent with that of hard-sphere and sticky-hard-sphere liquids predicted by more sophisticated liquid state theory and computer simulation. © 2012 American Institute of Physics
Behavioral correlates of anxiety in well-functioning older adults.
Losada, Andrés; Márquez-González, María; Pachana, Nancy A; Wetherell, Julie L; Fernández-Fernández, Virginia; Nogales-González, Celia; Ruiz-Díaz, Miguel
2015-07-01
Research on the behavioral correlates of anxiety in older adults is sparse. The aim of this study was to explore the association of anxiety with behavioral patterns defined by health, activity, emotional and social variables. A convenience sample of 395 older adults completed measures of health, activity, emotions, social variables and experiential avoidance. Cross-sectional data were analysed using cluster analysis. Five clusters were identified: active healthy, healthy, active vulnerable, lonely inactive and frail lonely. Participants in the active healthy and healthy clusters showed the highest scores on health variables (vitality and physical function), and adaptive scores on the rest of variables. They also reported the lowest scores on anxiety and included the lowest number of cases with clinically significant anxiety levels. Active vulnerable showed high scores on social support, leisure activities and capitalization on them but low scores in vitality and physical functioning. Participants in the lonely inactive cluster reported the highest mean score in experiential avoidance and high scores on boredom and loneliness, and low scores on social support, leisure activities capitalizing on pleasant activities and health variables. Frail lonely represent a particularly vulnerable profile of participants, similar to that of lonely inactive, but with significantly lower scores on health variables and higher scores on boredom and hours watching TV. Anxiety in older adults is not only linked to poor health, but also to dysfunctional social behavior, loneliness, boredom and experiential avoidance. Maladaptive profiles of older adults with regard to these variables have been identified.
Directory of Open Access Journals (Sweden)
J. Nastula
1997-11-01
Full Text Available The atmospheric influence on the Earth's, rotation can be described by the effective atmospheric angular momentum (EAAM functions. In this study we focus on the analysis of short period variations of the equatorial components of the zonal EAAM excitation functions χ1 and χ2 and their influence on similar variations of polar motion. The global objective analysis data of the Japanese Meteorological Agency for the period 1986–1992 were used to compute the EAAM excitation functions in different latitude belts. Time- and latitude-variable amplitude spectra of variations of these functions with periods shorter than 150 days, containing pressure, pressure with the inverted barometric correction, and wind terms were computed. The spectra show distinct latitude and time variations of the prograde and retrograde oscillations which reach their maxima mainly in mid-latitudes. Prograde and retrograde oscillations with periods of about 40–60 days and about 110–120 days are seen in the spectra of pressure terms of the equatorial components of the zonal EAAM excitation functions. Additionally, correlation coefficients and cross-spectra between variations of the geodetic polar motion and equatorial components of the zonal EAAM excitation functions were computed to identify the latitude belts of the globe over which atmospheric circulation changes are correlated mostly with short period variations of the polar motion excitation functions. The correlation coefficients vary in time and latitude and reach maximum values in the northern latitudes from 50°N to 60°N. In the cross-spectra between the polar motion excitation functions and pressure terms of the zonal EAAM excitation functions there are peaks of common prograde oscillations with the periods around 20, 30, 40–50, 60 and 80–150 days and of common retrograde oscillations around 20, 30, 40 and 50–70 days.
Directory of Open Access Journals (Sweden)
J. Nastula
Full Text Available The atmospheric influence on the Earth's, rotation can be described by the effective atmospheric angular momentum (EAAM functions. In this study we focus on the analysis of short period variations of the equatorial components of the zonal EAAM excitation functions χ_{1} and χ_{2} and their influence on similar variations of polar motion. The global objective analysis data of the Japanese Meteorological Agency for the period 1986–1992 were used to compute the EAAM excitation functions in different latitude belts. Time- and latitude-variable amplitude spectra of variations of these functions with periods shorter than 150 days, containing pressure, pressure with the inverted barometric correction, and wind terms were computed. The spectra show distinct latitude and time variations of the prograde and retrograde oscillations which reach their maxima mainly in mid-latitudes. Prograde and retrograde oscillations with periods of about 40–60 days and about 110–120 days are seen in the spectra of pressure terms of the equatorial components of the zonal EAAM excitation functions. Additionally, correlation coefficients and cross-spectra between variations of the geodetic polar motion and equatorial components of the zonal EAAM excitation functions were computed to identify the latitude belts of the globe over which atmospheric circulation changes are correlated mostly with short period variations of the polar motion excitation functions. The correlation coefficients vary in time and latitude and reach maximum values in the northern latitudes from 50^{°}N to 60^{°}N. In the cross-spectra between the polar motion excitation functions and pressure terms of the zonal EAAM excitation functions there are peaks of common prograde oscillations with the periods around 20, 30, 40–50, 60 and 80–150 days and of common retrograde oscillations around 20, 30, 40 and 50–70 days.
Temporal discrimination, a cervical dystonia endophenotype: penetrance and functional correlates.
Kimmich, Okka; Molloy, Anna; Whelan, Robert; Williams, Laura; Bradley, David; Balsters, Joshua; Molloy, Fiona; Lynch, Tim; Healy, Daniel G; Walsh, Cathal; O'Riordan, Seán; Reilly, Richard B; Hutchinson, Michael
2014-05-01
The pathogenesis of adult-onset primary dystonia remains poorly understood. There is variable age-related and gender-related expression of the phenotype, the commonest of which is cervical dystonia. Endophenotypes may provide insight into underlying genetic and pathophysiological mechanisms of dystonia. The temporal discrimination threshold (TDT)-the shortest time interval at which two separate stimuli can be detected as being asynchronous-is abnormal both in patients with cervical dystonia and in their unaffected first-degree relatives. Functional magnetic resonance imaging (fMRI) studies have shown that putaminal activation positively correlates with the ease of temporal discrimination between two stimuli in healthy individuals. We hypothesized that abnormal temporal discrimination would exhibit similar age-related and gender-related penetrance as cervical dystonia and that unaffected relatives with an abnormal TDT would have reduced putaminal activation during a temporal discrimination task. TDTs were examined in a group of 192 healthy controls and in 158 unaffected first-degree relatives of 84 patients with cervical dystonia. In 24 unaffected first-degree relatives, fMRI scanning was performed during a temporal discrimination task. The prevalence of abnormal TDTs in unaffected female relatives reached 50% after age 48 years; whereas, in male relatives, penetrance of the endophenotype was reduced. By fMRI, relatives who had abnormal TDTs, compared with relatives who had normal TDTs, had significantly less activation in the putamina and in the middle frontal and precentral gyri. Only the degree of reduction of putaminal activity correlated significantly with worsening of temporal discrimination. These findings further support abnormal temporal discrimination as an endophenotype of cervical dystonia involving disordered basal ganglia circuits. © 2014 International Parkinson and Movement Disorder Society.
Transport through correlated systems with density functional theory.
Kurth, S; Stefanucci, G
2017-10-18
We present recent advances in density functional theory (DFT) for applications in the field of quantum transport, with particular emphasis on transport through strongly correlated systems. We review the foundations of the popular Landauer-Büttiker(LB) + DFT approach. This formalism, when using approximations to the exchange-correlation (xc) potential with steps at integer occupation, correctly captures the Kondo plateau in the zero bias conductance at zero temperature but completely fails to capture the transition to the Coulomb blockade (CB) regime as the temperature increases. To overcome the limitations of LB + DFT, the quantum transport problem is treated from a time-dependent (TD) perspective using TDDFT, an exact framework to deal with nonequilibrium situations. The steady-state limit of TDDFT shows that in addition to an xc potential in the junction, there also exists an xc correction to the applied bias. Open shell molecules in the CB regime provide the most striking examples of the importance of the xc bias correction. Using the Anderson model as guidance we estimate these corrections in the limit of zero bias. For the general case we put forward a steady-state DFT which is based on one-to-one correspondence between the pair of basic variables, steady density on and steady current across the junction and the pair local potential on and bias across the junction. Like TDDFT, this framework also leads to both an xc potential in the junction and an xc correction to the bias. Unlike TDDFT, these potentials are independent of history. We highlight the universal features of both xc potential and xc bias corrections for junctions in the CB regime and provide an accurate parametrization for the Anderson model at arbitrary temperatures and interaction strengths, thus providing a unified DFT description for both Kondo and CB regimes and the transition between them.
The Galaxy Count Correlation Function in Redshift Space Revisited
Campagne, J.-E.; Plaszczynski, S.; Neveu, J.
2017-08-01
In the near future, cosmology will enter the wide and deep galaxy survey era, enabling high-precision studies of the large-scale structure of the universe in three dimensions. To test cosmological models and determine their parameters accurately, it is necessary to use data with exact theoretical expectations expressed in observational parameter space (angles and redshift). The data-driven, galaxy number count fluctuations on redshift shells can be used to build correlation functions ξ (θ ,{z}1,{z}2) on and between shells to probe the baryonic acoustic oscillations and distance-redshift distortions, as well as gravitational lensing and other relativistic effects. To obtain a numerical estimation of ξ (θ ,{z}1,{z}2) from a cosmological model, it is typical to use either a closed form derived from a tripolar spherical expansion or to compute the power spectrum {C}{\\ell }({z}1,{z}2) and perform a Legendre polynomial {P}{\\ell }(\\cos θ ) expansion. Here, we present a new derivation of a ξ (θ ,{z}1,{z}2) closed form using the spherical harmonic expansion and proceeding to an infinite sum over multipoles thanks to an addition theorem. We demonstrate that this new expression is perfectly compatible with the existing closed forms but is simpler to establish and manipulate. We provide formulas for the leading density and redshift-space contributions, but also show how Doppler-like and lensing terms can be easily included in this formalism. We have implemented and made publicly available software for computing those correlations efficiently, without any Limber approximation, and validated this software with the CLASSgal code. It is available at https://gitlab.in2p3.fr/campagne/AngPow.
Spatial correlation function of galaxies confronted with the theoretical scenarios
Energy Technology Data Exchange (ETDEWEB)
Dekel, A.; Aarseth, S.J.
1984-08-01
We study the two-point spatial corrlation function of galaxies, xi(r), in a series of numerical simulations of cosmological clustering scenarios in comparison with xi(r) obtained from redshift samples. The observed excess of correlation in the range 2--10 Mpc h/sup -1/, which does not agree with a pure hierarchial clustering scenario, is reproduced in a scenario where lambda = 30 +- 5 Mpc h/sup -1/ superclusters collapse first to flat (or elongated) ''pancakes.'' The flat slope of xi(r) in that region (..gamma..<1.8) is suggested to arise from this ''pancaking,'' i.e., the transition from a 3D distribution to a 2D (or a 1D) distribution in superclusters. The correlation below 2 Mpc h/sup -1/ reflects the presence of clusters that grow from perturbations on smaller scales which are either primordial or induced by nonlinear coupling of the large-scale perturbations. A concave break at 2--3 Mpc h/sup -1/ marks the present size of rich clusters, which continues to grow gradually in comoving coordinates. The shape of xi(r) is reproduced provided that the first pancaking occurred at z< or =0.5 if ..cap omega.. = 1 and at z<2 if ..cap omega../sub 0/ = 0.1. Later, its slope becomes too steep, and indistinguishable from the one obtained in the pure clustering scenario, because the gradual clustering approaches the scale of superclusters, causing the pancakes to break up into a few huge clusters.
Transport through correlated systems with density functional theory
Kurth, S.; Stefanucci, G.
2017-10-01
We present recent advances in density functional theory (DFT) for applications in the field of quantum transport, with particular emphasis on transport through strongly correlated systems. We review the foundations of the popular Landauer–Büttiker(LB) + DFT approach. This formalism, when using approximations to the exchange-correlation (xc) potential with steps at integer occupation, correctly captures the Kondo plateau in the zero bias conductance at zero temperature but completely fails to capture the transition to the Coulomb blockade (CB) regime as the temperature increases. To overcome the limitations of LB + DFT, the quantum transport problem is treated from a time-dependent (TD) perspective using TDDFT, an exact framework to deal with nonequilibrium situations. The steady-state limit of TDDFT shows that in addition to an xc potential in the junction, there also exists an xc correction to the applied bias. Open shell molecules in the CB regime provide the most striking examples of the importance of the xc bias correction. Using the Anderson model as guidance we estimate these corrections in the limit of zero bias. For the general case we put forward a steady-state DFT which is based on one-to-one correspondence between the pair of basic variables, steady density on and steady current across the junction and the pair local potential on and bias across the junction. Like TDDFT, this framework also leads to both an xc potential in the junction and an xc correction to the bias. Unlike TDDFT, these potentials are independent of history. We highlight the universal features of both xc potential and xc bias corrections for junctions in the CB regime and provide an accurate parametrization for the Anderson model at arbitrary temperatures and interaction strengths, thus providing a unified DFT description for both Kondo and CB regimes and the transition between them.
Choi, Ji Yeh; Hwang, Heungsun; Yamamoto, Michio; Jung, Kwanghee; Woodward, Todd S
2017-06-01
Functional principal component analysis (FPCA) and functional multiple-set canonical correlation analysis (FMCCA) are data reduction techniques for functional data that are collected in the form of smooth curves or functions over a continuum such as time or space. In FPCA, low-dimensional components are extracted from a single functional dataset such that they explain the most variance of the dataset, whereas in FMCCA, low-dimensional components are obtained from each of multiple functional datasets in such a way that the associations among the components are maximized across the different sets. In this paper, we propose a unified approach to FPCA and FMCCA. The proposed approach subsumes both techniques as special cases. Furthermore, it permits a compromise between the techniques, such that components are obtained from each set of functional data to maximize their associations across different datasets, while accounting for the variance of the data well. We propose a single optimization criterion for the proposed approach, and develop an alternating regularized least squares algorithm to minimize the criterion in combination with basis function approximations to functions. We conduct a simulation study to investigate the performance of the proposed approach based on synthetic data. We also apply the approach for the analysis of multiple-subject functional magnetic resonance imaging data to obtain low-dimensional components of blood-oxygen level-dependent signal changes of the brain over time, which are highly correlated across the subjects as well as representative of the data. The extracted components are used to identify networks of neural activity that are commonly activated across the subjects while carrying out a working memory task.
Spline function fit for multi-sets of correlative data
International Nuclear Information System (INIS)
Liu Tingjin; Zhou Hongmo
1992-01-01
The Spline fit method for multi-sets of correlative data is developed. The properties of correlative data fit are investigated. The data of 23 Na(n, 2n) cross section are fitted in the cases with and without correlation
Atmospheric stellar parameters from cross-correlation functions
Malavolta, L.; Lovis, C.; Pepe, F.; Sneden, C.; Udry, S.
2017-08-01
The increasing number of spectra gathered by spectroscopic sky surveys and transiting exoplanet follow-up has pushed the community to develop automated tools for atmospheric stellar parameters determination. Here we present a novel approach that allows the measurement of temperature (Teff), metallicity ([Fe/H]) and gravity (log g) within a few seconds and in a completely automated fashion. Rather than performing comparisons with spectral libraries, our technique is based on the determination of several cross-correlation functions (CCFs) obtained by including spectral features with different sensitivity to the photospheric parameters. We use literature stellar parameters of high signal-to-noise (SNR), high-resolution HARPS spectra of FGK main-sequence stars to calibrate Teff, [Fe/H] and log g as a function of CCF parameters. Our technique is validated using low-SNR spectra obtained with the same instrument. For FGK stars we achieve a precision of σ _{{T_eff}} = 50 K, σlog g = 0.09 dex and σ _{{{[Fe/H]}}} =0.035 dex at SNR = 50, while the precision for observation with SNR ≳ 100 and the overall accuracy are constrained by the literature values used to calibrate the CCFs. Our approach can easily be extended to other instruments with similar spectral range and resolution or to other spectral range and stars other than FGK dwarfs if a large sample of reference stars is available for the calibration. Additionally, we provide the mathematical formulation to convert synthetic equivalent widths to CCF parameters as an alternative to direct calibration. We have made our tool publicly available.
Integrable dissipative exclusion process: Correlation functions and physical properties
Crampe, N.; Ragoucy, E.; Rittenberg, V.; Vanicat, M.
2016-09-01
We study a one-parameter generalization of the symmetric simple exclusion process on a one-dimensional lattice. In addition to the usual dynamics (where particles can hop with equal rates to the left or to the right with an exclusion constraint), annihilation and creation of pairs can occur. The system is driven out of equilibrium by two reservoirs at the boundaries. In this setting the model is still integrable: it is related to the open XXZ spin chain through a gauge transformation. This allows us to compute the full spectrum of the Markov matrix using Bethe equations. We also show that the stationary state can be expressed in a matrix product form permitting to compute the multipoints correlation functions as well as the mean value of the lattice and the creation-annihilation currents. Finally, the variance of the lattice current is computed for a finite-size system. In the thermodynamic limit, it matches the value obtained from the associated macroscopic fluctuation theory.
EEG correlates of time-varying BOLD functional connectivity
Chang, Catie; Liu, Zhongming; Chen, Michael C.; Liu, Xiao; Duyn, Jeff H.
2013-01-01
Recent resting-state fMRI studies have shown that the apparent functional connectivity (FC) between brain regions may undergo changes on time-scales of seconds to minutes, the basis and importance of which are largely unknown. Here, we examine the electrophysiological correlates of within-scan FC variations during a condition of eyes-closed rest. A sliding window analysis of simultaneous EEG-fMRI data was performed to examine whether temporal variations in coupling between three major networks (default mode; DMN, dorsal attention; DAN, and salience network; SN) are associated with temporal variations in mental state, as assessed from the amplitude of alpha and theta oscillations in the EEG. In our dataset, alpha power showed a significant inverse relationship with the strength of connectivity between DMN and DAN. In addition, alpha power covaried with the spatial extent of anticorrelation between DMN and DAN, with higher alpha power associated with larger anticorrelation extent. Results suggest an electrical signature of the time-varying FC between the DAN and DMN, potentially reflecting neural and state-dependent variations. PMID:23376790
Local Approximation of the Correlation Energy Functional in the Density Matrix Functional Theory
Yasuda, Koji
2002-02-01
A local approximation formula of the correlation energy functional Ec in terms of the first-order reduced density matrix (1-RDM) is presented. With the contracted Schrödinger equation the principal dependence of Ec on the natural occupation numbers ni is identified. Using the effective mass theory, Ec is expressed as a functional of the local density and the local variable, J = Σi(ni(1-ni)) \\|ϕi\\|2, where ϕi are the natural spin orbitals. This local approximation satisfies the homogeneous coordinate scaling relation, gives the exact result for a one-electron system, and is almost free from the exchange energy error. It reproduced about 90% of the correlation energies of atoms and molecules.
On soft limits of large-scale structure correlation functions
International Nuclear Information System (INIS)
Sagunski, Laura
2016-08-01
Large-scale structure surveys have the potential to become the leading probe for precision cosmology in the next decade. To extract valuable information on the cosmological evolution of the Universe from the observational data, it is of major importance to derive accurate theoretical predictions for the statistical large-scale structure observables, such as the power spectrum and the bispectrum of (dark) matter density perturbations. Hence, one of the greatest challenges of modern cosmology is to theoretically understand the non-linear dynamics of large-scale structure formation in the Universe from first principles. While analytic approaches to describe the large-scale structure formation are usually based on the framework of non-relativistic cosmological perturbation theory, we pursue another road in this thesis and develop methods to derive generic, non-perturbative statements about large-scale structure correlation functions. We study unequal- and equal-time correlation functions of density and velocity perturbations in the limit where one of their wavenumbers becomes small, that is, in the soft limit. In the soft limit, it is possible to link (N+1)-point and N-point correlation functions to non-perturbative 'consistency conditions'. These provide in turn a powerful tool to test fundamental aspects of the underlying theory at hand. In this work, we first rederive the (resummed) consistency conditions at unequal times by using the so-called eikonal approximation. The main appeal of the unequal-time consistency conditions is that they are solely based on symmetry arguments and thus are universal. Proceeding from this, we direct our attention to consistency conditions at equal times, which, on the other hand, depend on the interplay between soft and hard modes. We explore the existence and validity of equal-time consistency conditions within and beyond perturbation theory. For this purpose, we investigate the predictions for the soft limit of the
A COSMIC COINCIDENCE: THE POWER-LAW GALAXY CORRELATION FUNCTION
International Nuclear Information System (INIS)
Watson, Douglas F.; Berlind, Andreas A.; Zentner, Andrew R.
2011-01-01
We model the evolution of galaxy clustering through cosmic time to investigate the nature of the power-law shape of ξ(r), the galaxy two-point correlation function. While ξ(r) at large scales is set by primordial fluctuations, departures from a power law are governed by galaxy pair counts at small scales, subject to nonlinear dynamics. We assume that galaxies reside within dark matter halos and subhalos. Therefore, the shape of the correlation function at small scales depends on the amount of halo substructure. We use a semi-analytic substructure evolution model to study subhalo populations within host halos. We find that tidal mass loss and, to a lesser extent, dynamical friction dramatically deplete the number of subhalos within larger host halos over time, resulting in a ∼90% reduction by z = 0 compared to the number of distinct mergers that occur during the assembly of a host halo. We show that these nonlinear processes resulting in this depletion are essential for achieving a power law ξ(r). We investigate how the shape of ξ(r) depends on subhalo mass (or luminosity) and redshift. We find that ξ(r) breaks from a power law at high masses, implying that only galaxies of luminosities ∼ * should exhibit power-law clustering. Moreover, we demonstrate that ξ(r) evolves from being far from a power law at high redshift, toward a near power-law shape at z = 0. We argue that ξ(r) will once again evolve away from a power law in the future. This is in large part caused by the evolving competition between the accretion and destruction rates of subhalos over time, which happen to strike just the right balance at z ∼ 0. We then investigate the conditions required for ξ(r) to be a power law in a general context. We use the halo model, along with simple parameterizations of the halo occupation distribution, to probe galaxy occupation at various masses and redshifts. We show that the key ingredients determining the shape of ξ(r) are the fraction of galaxies that
Pair-correlation function in disordered β-brass as studied by neutron diffraction
DEFF Research Database (Denmark)
Als-Nielsen, Jens Aage; Dietrich, O.W.
1967-01-01
Critical neutron scattering around a superlattice reflection above Tc yields information on the pair correlation function for occupation of lattice sites. The Ornstein-Zernike correlation function e-k 1 r/r is proved to fit the data excellently, and at 8.9deg K above Tc the inverse correlation...
Light scalar mesons and two-kaon correlation functions
Achasov, N. N.; Kiselev, A. V.
2018-02-01
It is shown that the recent data on the KS0K+ correlation in Pb-Pb interactions agree with the data on the γ γ →η π0 and ϕ →η π0γ reactions and support the four-quark model of the a0(980 ) meson. It is shown that the data does not contradict the validity of the Gaussian assumption. The study of two-kaon correlations could provide more information about light scalar mesons after increasing the accuracy of the experimental and theoretical descriptions.
Structurofunctional resting-state networks correlate with motor function in chronic stroke
Directory of Open Access Journals (Sweden)
Benjamin T. Kalinosky
2017-01-01
Conclusion: The results demonstrate that changes after a stroke in both intrinsic and network-based structurofunctional correlations at rest are correlated with motor function, underscoring the importance of residual structural connectivity in cortical networks.
Two Point Correlation Functions for a Periodic Box-Ball System
Directory of Open Access Journals (Sweden)
Jun Mada
2011-03-01
Full Text Available We investigate correlation functions in a periodic box-ball system. For the second and the third nearest neighbor correlation functions, we give explicit formulae obtained by combinatorial methods. A recursion formula for a specific N-point functions is also presented.
Studies in the method of correlated basis functions. Pt. 3
International Nuclear Information System (INIS)
Krotscheck, E.; Clark, J.W.
1980-01-01
A variational theory of pairing phenomena is presented for systems like neutron matter and liquid 3 He. The strong short-range correlations among the particles in these systems are incorporated into the trial states describing normal and pair-condensed phases, via a correlation operator F. The resulting theory has the same basic structure as that ordinarily applied for weak two-body interactions; in place of the pairing matrix elements of the bare interaction one finds certain effective pairing matrix elements Psub(kl), and modified single particle energies epsilon (k) appear. Detailed prescriptions are given for the construction of the Psub(kl) and epsilon (k) in terms of off-diagonal and diagonal matrix elements of the Hamiltonian and unit operators in a correlated basis of normal states. An exact criterion for instability of the assumed normal phase with respect to pair condensation is derived for general F. This criterion is investigated numerically for the special case if Jastrow correlations, the required normal-state quantities being evaluated by integral equation techniques which extend the Fermi hypernetted-chain scheme. In neutron matter, an instability with respect to 1 S 0 pairing is found in the low-density region, in concert with the predictions of Yang and Clark. In liquid 3 He, there is some indication of a 3 P 0 pairing instability in the vicinity of the experimental equilibrium density. (orig.)
Directory of Open Access Journals (Sweden)
Arsić Slađana
2016-01-01
Full Text Available Introduction. It has been assumed that there is causality of the achieved level of functional independence with the degree of preservation of cognitive function in stroke patients. Demographic characteristics may be important for monitoring the achieved level of functional independence. Objective. The aim of this study was to examine the relationship of demographic characteristics and functional independence in regard to the level of cognitive impairment in stroke patients. Methods. The study included 50 stroke patients after rehabilitation, as well as age- and gender-matched 50 subjects selected randomly, according to the demographic characteristics of the studied sample, who in their medical history had no neurological disorders. For the assessment of functional independence, the Functional Independence Measure (FIM test was used. The general cognition was estimated by the Mini-Mental State Examination (MMSE test. The statistical analyses included the Mann-Whitney test, for two independent samples, measures of canonical correlation, and χ2 test. Results. There was a statistically significant difference between the groups in relation to risk factors, hypertension and diabetes mellitus type II (p<0.001; There was a statistically significant difference within the groups in relation to the cognitive impairment in all the examined demographic characteristics (p<0.001; the differences within the groups in relation to the cognitive impairment are present on all subscales of the FIM test (p<0.05; the differences within the groups in relation to handedness, hemiparesis, show that mild cognitive impairment is more common among left hemiparesis, while a more severe one is more common among right-sided hemiparesis (p<0.05; More severe cognitive impairment is common among women, the elderly and in persons with lower education (p<0.05. Conclusion. By prevention of risk factors, and prevention of possible cognitive impairment, consequences of stroke can be
Killgore, William D S
2013-11-01
Prior research suggests that sleep deprivation is associated with declines in some aspects of emotional intelligence and increased severity on indices of psychological disturbance. Sleep deprivation is also associated with reduced prefrontal-amygdala functional connectivity, potentially reflecting impaired top-down modulation of emotion. It remains unknown whether this modified connectivity may be observed in relation to more typical levels of sleep curtailment. We examined whether self-reported sleep duration the night before an assessment would be associated with these effects. Participants documented their hours of sleep from the previous night, completed the Bar-On Emotional Quotient Inventory (EQ-i), Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT), and Personality Assessment Inventory (PAI), and underwent resting-state functional magnetic resonance imaging (fMRI). Outpatient neuroimaging center at a private psychiatric hospital. Sixty-five healthy adults (33 men, 32 women), ranging in age from 18-45 y. N/A. Greater self-reported sleep the preceding night was associated with higher scores on all scales of the EQ-i but not the MSCEIT, and with lower symptom severity scores on half of the psychopathology scales of the PAI. Longer sleep was also associated with stronger negative functional connectivity between the right ventromedial prefrontal cortex and amygdala. Moreover, greater negative connectivity between these regions was associated with higher EQ-i and lower symptom severity on the PAI. Self-reported sleep duration from the preceding night was negatively correlated with prefrontal-amygdala connectivity and the severity of subjective psychological distress, while positively correlated with higher perceived emotional intelligence. More sleep was associated with higher emotional and psychological strength.
Pounraj, P.; Mohankumar, V.; Pandian, Muthu Senthil; Ramasamy, P.
2017-05-01
Three triphenylamine based dyes (Dye 1, 2 & 3) and three anthocyanin modified triphenylamine based dyes (Dye 4, 5 &6) are designed and the geometry, electronic structure and absorption spectra of newly designed dyes were investigated by density functional theory (DFT) and time dependent density functional theory (TD-DFT) with the Becke 3-Parameter-Lee-Yang-Parr (B3LYP) functional, where the 6-311++G (d, p) basis set was employed. All calculations were performed using the Gaussian 09 software package. The lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO) energy level of these dyes could ensure the positive effect on the process of electron injection and dye regeneration. The LUMOs are just above the conduction band of TiO2 and their HOMOs are under the reduction potential energy of the electrolytes (I-/I3-) which can facilitate electron transfer from the excited dye to TiO2 and charge regeneration process after photo oxidation respectively. The simulated absorption spectrum of dyes matches with solar spectrum. The simulated absorption spectrum of dyes shows better absorption. The calculated quantum mechanical results shows that among all six dyes, the "dye 6" can be used as potential sensitizer for DSSC.
Triphenylamine based organic dyes for dye sensitized solar cells: A theoretical approach
Energy Technology Data Exchange (ETDEWEB)
Mohankumar, V.; Pandian, Muthu Senthil; Ramasamy, P., E-mail: ramasamyp@ssn.edu.in [SSN Research Centre, SSN College of Engineering, Chennai-603110, Tamilnadu (India)
2016-05-23
The geometry, electronic structure and absorption spectra for newly designed triphenylamine based organic dyes were investigated by density functional theory (DFT) and time dependent density functional theory (TD-DFT) with the Becke 3-Parameter-Lee-Yang-parr(B3LYP) functional, where the 6-31G(d,p) basis set was employed. All calculations were performed using the Gaussian 09 software package. The calculated HOMO and LUMO energies show that charge transfer occurs in the molecule. Ultraviolet–visible (UV–vis) spectrum was simulated by TD-DFT in gas phase. The calculation shows that all of the dyes can potentially be good sensitizers for DSSC. The LUMOs are just above the conduction band of TiO{sub 2} and their HOMOs are under the reduction potential energy of the electrolytes (I{sup −}/I{sub 3}{sup −}) which can facilitate electron transfer from the excited dye to TiO{sub 2} and charge regeneration process after photo oxidation respectively. The simulated absorption spectrum of dyes match with solar spectrum. Frontier molecular orbital results show that among all the three dyes, the “dye 3” can be used as potential sensitizer for DSSC.
Amalanathan, M.; Jasmine, G. Femina; Roy, S. Dawn Dharma
2017-08-01
The molecular structure, vibrational spectra and polarizabilities of Ethyl 4-Dimethylaminobenzoate (EDAB) was investigated by density functional theory employing Becke's three parameter hybrid exchange functional with Lee-Yang-Parr (B3LYP) co-relational functional involving 6-311++G(d,p) basis set and compared with some other levels. A detailed interpretation of the IR and Raman spectra of EDBA have been reported and analyzed. Complete vibrational assignments of the vibrational modes have been done on the basis of the potential energy distribution (TED) using VEDA software. The molecular electrostatic potential mapped onto total density surface has been obtained. A study on the electronic properties, such as absorption wavelength, and frontier molecular orbitals energy, was performed using DFT approach. The stability of the molecule arising from hyper conjugative interactions and accompanying charge delocalization has been analyzed using natural bond orbital (NBO) analysis. The natural and Mulliken charge also calculated and compared with different level of calculation. The dipole moment, polarizability and first, second order hyperpolarizabilities of the title molecule were calculated and compared with the experimental values. The energy gap between frontier orbitals has been used along with electric moments and first order hyperpolarizability, to understand the non linear optical (NLO) activity of the molecule. The NLO activity of molecule was confirmed by SHG analysis.
Cluster expansions for the correlated basis functions theory
Energy Technology Data Exchange (ETDEWEB)
Guardiola, R. (Granada Univ. (Spain). Dept. de Fisica Nuclear)
1982-08-16
Four kinds of cluster expansions for the calculation of non-diagonal matrix elements of the hamiltonian between correlated states have been derived. The derivation is based on a linearization mechanism for the standard cluster expansions in a configuration mixed state. Particulary simple formulae result for the multiplicative Factor-Aviles-Hartog-Tolhoek expansion and for the exponential form of the Gaudin-Gillespie-Ripka cluster expansion. The resulting expansions are directly usable in finite nuclei.
A study of electron momentum density distribution in Al2O3 ceramic
Vyas, V.; Kumar, R.; Mishra, M. C.; Sharma, G.; Sharma, B. K.
2011-08-01
A study of electron momentum density distribution in α-Al2O3 ceramic using Compton spectroscopy is presented in this work. Measurements have been carried out using 59.54 keV gamma-rays emanating from an Am241 source. Calculations have been performed on the basis of the ab-initio linear combination of atomic orbitals (LCAO) method embodied in the CRYSTAL code. The correlation scheme proposed by Perdew-Burke-Ernzerhof was adopted. The exchange was treated following the Becke scheme. The Hartree-Fock and hybrid schemes were also applied to the compound. All the schemes yielded results that are in good agreement with the measurements. The agreement with experiment is, however, better with the hybrid B3LYP (Lee-Yang-Parr) scheme. Ionic model calculations for a number of configurations of (Al+x)2(O-2x/3)3 (2.75<=x<=3 in steps of 0.125) were also performed utilizing free atom profiles. The ionic model suggests transfer of 2.875 electrons from the valence sp state of Al to the p state of O.
A study of electron momentum density distribution in Al{sub 2}O{sub 3} ceramic
Energy Technology Data Exchange (ETDEWEB)
Vyas, V; Sharma, G [Department of Physics, Banasthali University, Banasthali-304022 (India); Kumar, R; Mishra, M C; Sharma, B K, E-mail: gsphysics@gmail.com [Department of Physics, University of Rajasthan, Jaipur-302004 (India)
2011-08-01
A study of electron momentum density distribution in {alpha}-Al{sub 2}O{sub 3} ceramic using Compton spectroscopy is presented in this work. Measurements have been carried out using 59.54 keV gamma-rays emanating from an Am{sup 241} source. Calculations have been performed on the basis of the ab-initio linear combination of atomic orbitals (LCAO) method embodied in the CRYSTAL code. The correlation scheme proposed by Perdew-Burke-Ernzerhof was adopted. The exchange was treated following the Becke scheme. The Hartree-Fock and hybrid schemes were also applied to the compound. All the schemes yielded results that are in good agreement with the measurements. The agreement with experiment is, however, better with the hybrid B3LYP (Lee-Yang-Parr) scheme. Ionic model calculations for a number of configurations of (Al{sup +x}){sub 2}(O{sup -2x/3}){sub 3} (2.75{<=}x{<=}3 in steps of 0.125) were also performed utilizing free atom profiles. The ionic model suggests transfer of 2.875 electrons from the valence sp state of Al to the p state of O.
Directory of Open Access Journals (Sweden)
Cemal Parlak
2012-08-01
Full Text Available The normal mode frequencies and corresponding vibrational assignments, 1H and 13C NMR chemical shifts and structural parameters (bond lengths, bond and dihedral angles of 2-[(1E-2-aza-2-(5-methyl(2-pyridylethenyl]-4-bromobenzen-1-ol (2mpe-4bb Schiff base compound have been theoretically examined by means of Hartree-Fock (HF and Becke-3-Lee-Yang-Parr (B3LYP density functional methods with 6-31G(d and 6-311++G(d,p basis sets. Furthermore, reliable vibrational assignments have made on the basis of potential energy distribution (PED calculated and the thermodynamics functions, highest occupied and lowest unoccupied molecular orbitals (HOMO and LUMO of 2mpe-4bb have been predicted. Theoretical results have been successfully compared with available experimental data in the literature. Regarding the calculations, 2mpe-4bb prefers enol-imine form and DFT method is superior to HF approach except for predicting bond lengths.DOI: http://dx.doi.org/10.4314/bcse.v26i2.11
DFT study of the effect of substituents on the absorption and emission spectra of Indigo
Directory of Open Access Journals (Sweden)
Cervantes-Navarro Francisco
2012-07-01
Full Text Available Abstract Background Theoretical analyses of the indigo dye molecule and its derivatives with Chlorine (Cl, Sulfur (S, Selenium (Se and Bromine (Br substituents, as well as an analysis of the Hemi-Indigo molecule, were performed using the Gaussian 03 software package. Results Calculations were performed based on the framework of density functional theory (DFT with the Becke 3- parameter-Lee-Yang-Parr (B3LYP functional, where the 6-31 G(d,p basis set was employed. The configuration interaction singles (CIS method with the same basis set was employed for the analysis of excited states and for the acquisition of the emission spectra. Conclusions The presented absorption and emission spectra were affected by the substitution position. When a hydrogen atom of the molecule was substituted by Cl or Br, practically no change in the absorbed and emitted energies relative to those of the indigo molecule were observed; however, when N was substituted by S or Se, the absorbed and emitted energies increased.
Directory of Open Access Journals (Sweden)
Mohammad Shahidul Islam
2015-05-01
Full Text Available This paper describes an efficient and regioselective method for the synthesis of novel fluorinated spiro-heterocycles in excellent yield by cascade [5+1] double Michael addition reactions. The compounds 7,11-bis(4-fluorophenyl-2,4-dimethyl- 2,4-diazaspiro[5.5] undecane-1,3,5,9-tetraone (3a and 2,4-dimethyl-7,11-bis (4-(trifluoromethylphenyl-2,4-diazaspiro[5.5]undecane-1,3,5,9-tetraone (3b were characterized by single-crystal X-ray diffraction, FT-IR and NMR techniques. The optimized geometrical parameters, infrared vibrational frequencies and NMR chemical shifts of the studied compounds have also been calculated using the density functional theory (DFT method, using Becke-3-Lee-Yang-Parr functional and the 6-311G(d,p basis set. There is good agreement between the experimentally determined structural parameters, vibrational frequencies and NMR chemical shifts of the studied compounds and those predicted theoretically. The calculated natural atomic charges using NBO method showed higher polarity of 3a compared to 3b.The calculated electronic spectra are also discussed based on the TD-DFT calculations.
Sheela, N R; Sampathkrishnan, S; Thirumalai Kumar, M; Muthu, S
2013-05-15
The title compound, 2(2-Hydroxyphenyl)-N-(4-Methylphenyl) Nitrone (2HPN4MPN) was synthesized and characterized by FT-IR, FT-Raman, UV-Vis and (1)HNMR, (13)CNMR spectral analysis. The molecular geometry, harmonic vibrational frequencies and bonding features of the title compound in the ground state are computed at three parameter hybrid functional Lee-Yang-Parr/6-311++G(d,p) levels of theory. The most stable conformer of 2HPN4MPN is identified from the computational results. The assignments of the vibrational spectra have been carried out with the help of normal co-ordinate analysis (NCA) following the scaled quantum mechanical force field methodology (SQMF). The UV-Vis spectrum was recorded in chloroform solution. The energy and oscillator strength calculated by time-dependent density functional theory (TD-DFT) complements the experimental findings. The calculated HOMO and LUMO energies confirm that charge transfer occurs within the molecule. In addition, DFT calculations of the compound, Molecular Electrostatic Potential (MEP), Natural Bond Orbital analysis (NBO) and non-linear optical (NLO) properties are performed at B3LYP/6-311++G(d,p) level of theory. Finally, the calculations are applied to simulated FT-IR and FT-Raman spectra of the title compound which show good agreement with observed spectra. Copyright © 2013 Elsevier B.V. All rights reserved.
The Bell inequality and correlation of spin projection functions
International Nuclear Information System (INIS)
Andreev, V A
2009-01-01
The Bell inequality two-particle spin states are considered. It is shown that violation of this inequality at experimental verifications is connected with the fact that it is proved for some arbitrary random variables, but in experimental verification random variables of special type are used. A new inequality is constructed. It contains a correlation coefficient of random variables, measured at the experiment, and does not have to be violated at experimental verification. For factorizable and separable states it coincides with the usual Bell inequality.
International Nuclear Information System (INIS)
Sarmento, E.F.
1981-01-01
Results are found for the dynamical correlation functions (or its corresponding Green's functions) among any combination including operator pairs of electronic and nuclear spins in an antiferromagnet semi-infinite medium, at low temperatures T [pt
Cheng, Jin; Yu, Kuang; Libisch, Florian; Dieterich, Johannes M; Carter, Emily A
2017-03-14
Quantum mechanical embedding theories partition a complex system into multiple spatial regions that can use different electronic structure methods within each, to optimize trade-offs between accuracy and cost. The present work incorporates accurate but expensive correlated wave function (CW) methods for a subsystem containing the phenomenon or feature of greatest interest, while self-consistently capturing quantum effects of the surroundings using fast but less accurate density functional theory (DFT) approximations. We recently proposed two embedding methods [for a review, see: Acc. Chem. Res. 2014 , 47 , 2768 ]: density functional embedding theory (DFET) and potential functional embedding theory (PFET). DFET provides a fast but non-self-consistent density-based embedding scheme, whereas PFET offers a more rigorous theoretical framework to perform fully self-consistent, variational CW/DFT calculations [as defined in part 1, CW/DFT means subsystem 1(2) is treated with CW(DFT) methods]. When originally presented, PFET was only tested at the DFT/DFT level of theory as a proof of principle within a planewave (PW) basis. Part 1 of this two-part series demonstrated that PFET can be made to work well with mixed Gaussian type orbital (GTO)/PW bases, as long as optimized GTO bases and consistent electron-ion potentials are employed throughout. Here in part 2 we conduct the first PFET calculations at the CW/DFT level and compare them to DFET and full CW benchmarks. We test the performance of PFET at the CW/DFT level for a variety of types of interactions (hydrogen bonding, metallic, and ionic). By introducing an intermediate CW/DFT embedding scheme denoted DFET/PFET, we show how PFET remedies different types of errors in DFET, serving as a more robust type of embedding theory.
Social cognition in schizophrenia: factor structure, clinical and functional correlates.
Buck, Benjamin E; Healey, Kristin M; Gagen, Emily C; Roberts, David L; Penn, David L
2016-08-01
Social cognition is consistently impaired in people with schizophrenia, separable from general neurocognition, predictive of real-world functioning and amenable to psychosocial treatment. Few studies have empirically examined its underlying factor structure. This study (1) examines the factor structure of social cognition in both a sample of individuals with schizophrenia-spectrum disorders and non-clinical controls and (2) explores relationships of factors to neurocognition, symptoms and functioning. A factor analysis was conducted on social cognition measures in a sample of 65 individuals with schizophrenia or schizoaffective disorder, and 50 control participants. The resulting factors were examined for their relationships to symptoms and functioning. Results suggested a two-factor structure in the schizophrenia sample (social cognition skill and hostile attributional style) and a three-factor structure in the non-clinical sample (hostile attributional style, higher-level inferential processing and lower-level cue detection). In the schizophrenia sample, the social cognition skill factor was significantly related to negative symptoms and social functioning, whereas hostile attributional style predicted positive and general psychopathology symptoms. The factor structure of social cognition in schizophrenia separates hostile attributional style and social cognition skill, and each show differential relationships to relevant clinical variables in schizophrenia.
The MATRICS Consensus Cognitive Battery (MCCB): performance and functional correlates.
Lystad, June Ullevoldsæter; Falkum, Erik; Mohn, Christine; Haaland, Vegard Øksendal; Bull, Helen; Evensen, Stig; Rund, Bjørn Rishovd; Ueland, Torill
2014-12-30
Neurocognitive impairment is a core feature in psychotic disorders and the MATRICS Consensus Cognitive Battery (MCCB) is now widely used to assess neurocognition in this group. The MATRICS has been translated into several languages, including Norwegian; although this version has yet to be investigated in an adult clinical population. Further, the relationship between the MATRICS and different measures of functioning needs examination. The purpose of this study was to describe neurocognition assessed with the Norwegian version of the MATRICS battery in a sample of patients with psychotic disorders compared to age and gender matched healthy controls and to examine the association with educational-, occupational- and social-functioning in the patient group. One hundred and thirty one patients and 137 healthy controls completed the battery. The Norwegian version of the MATRICS was sensitive to the magnitude of neurocognitive impairments in patients with psychotic disorders, with patients displaying significant impairments on all domains relative to healthy controls. Neurocognition was also related to both self-rated and objective functional measures such as social functioning, educational- and employment-history. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Czech Academy of Sciences Publication Activity Database
Tran, F.; Blaha, P.; Schwarz, K.; Novák, Pavel
2006-01-01
Roč. 74, č. 15 (2006), 155108/1-155108/10 ISSN 1098-0121 R&D Projects: GA AV ČR(CZ) IAA1010214 EU Projects: European Commission(XE) HPRN-CT-2002-00293 - SCOOTMO Grant - others:Austrian Science Fondation(AT) AURORA project SFB011 Institutional research plan: CEZ:AV0Z10100521 Keywords : density functional theory * hybrid functional * transition metal monoxides Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 3.107, year: 2006
Stoichiometric Correlation Analysis: Principles of Metabolic Functionality from Metabolomics Data
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Kevin Schwahn
2017-12-01
Full Text Available Recent advances in metabolomics technologies have resulted in high-quality (time-resolved metabolic profiles with an increasing coverage of metabolic pathways. These data profiles represent read-outs from often non-linear dynamics of metabolic networks. Yet, metabolic profiles have largely been explored with regression-based approaches that only capture linear relationships, rendering it difficult to determine the extent to which the data reflect the underlying reaction rates and their couplings. Here we propose an approach termed Stoichiometric Correlation Analysis (SCA based on correlation between positive linear combinations of log-transformed metabolic profiles. The log-transformation is due to the evidence that metabolic networks can be modeled by mass action law and kinetics derived from it. Unlike the existing approaches which establish a relation between pairs of metabolites, SCA facilitates the discovery of higher-order dependence between more than two metabolites. By using a paradigmatic model of the tricarboxylic acid cycle we show that the higher-order dependence reflects the coupling of concentration of reactant complexes, capturing the subtle difference between the employed enzyme kinetics. Using time-resolved metabolic profiles from Arabidopsis thaliana and Escherichia coli, we show that SCA can be used to quantify the difference in coupling of reactant complexes, and hence, reaction rates, underlying the stringent response in these model organisms. By using SCA with data from natural variation of wild and domesticated wheat and tomato accession, we demonstrate that the domestication is accompanied by loss of such couplings, in these species. Therefore, application of SCA to metabolomics data from natural variation in wild and domesticated populations provides a mechanistic way to understanding domestication and its relation to metabolic networks.
Development and testing of new exchange correlation functionals
DEFF Research Database (Denmark)
Lundgård, Keld Troen
Catalysts are used in 90% of the world’s chemical processes to produce 60% of its chemical products, and they are thus very important to our modern society. We therefore seek to better understand current catalytic materials, so that we can find alternatives that will improve the energy efficiency......, selectivity or similar of current chemical processes, or to make new technologies economical feasible. Kohn-Sham density functional theory (KS-DFT) has proven to be a powerful theory to find trends in current catalytic materials, which can empower a more informed search for better alternatives. KS-DFT relies...... generally applicable models; a robust MM-estimator loss function, for ensuring resistance to outliers in data; and a hierarchical bootstrap resampling estimating prediction error validation method, for selecting the model complexity that provide best transferability outside the training data. Three new semi...
Correlates of wellness among youth with functional disabilities.
Menear, K S; Preskitt, J K; Goldfarb, S S; Menachemi, N
2015-04-01
The literature is more informative on the impediments to wellness among youth with functional limitations and less instructive on the state of wellness for this population. To explore overall wellness, and each sub-dimension of wellness, in a national sample of youth with functional limitations and to determine how demographic characteristics are associated with wellness. Using a previously validated screening instrument, we identify youth with functional limitations aged 12 to 17 represented in the 2011/12 National Survey of Children's Health. Survey items were coded to operationalize an overall wellness score comprised of four sub-dimensions of wellness (i.e., physical, intellectual, emotional, and social). The mean overall wellness score was 26.7 (out of 40) and had an approximate normal distribution. Mean raw scores for each sub-dimension were as follows: social = 2.79 (out of 4; 69.7%); emotional = 4.09 (out of 6; 68.2%); intellectual = 3.79 (out of 8; 47.4%); and physical = 6.30 (out of 8; 78.7%). Lower wellness scores were associated with older age among youth, increasing number of chronic health conditions, lower income, single mother homes, and youth whose mother reported fair or poor mental health status (all p wellness scores were positively associated with mother's education (p wellness and promote family involvement and comprehensive supports, including maternal educational attainment, mental health screening, and referral. Copyright © 2015 Elsevier Inc. All rights reserved.
Functional neural correlates of reduced physiological falls risk.
Nagamatsu, Lindsay S; Hsu, Chun Liang; Handy, Todd C; Liu-Ambrose, Teresa
2011-08-16
It is currently unclear whether the function of brain regions associated with executive cognitive processing are independently associated with reduced physiological falls risk. If these are related, it would suggest that the development of interventions targeted at improving executive neurocognitive function would be an effective new approach for reducing physiological falls risk in seniors. We performed a secondary analysis of 73 community-dwelling senior women aged 65 to 75 years old who participated in a 12-month randomized controlled trial of resistance training. Functional MRI data were acquired while participants performed a modified Eriksen Flanker Task - a task of selective attention and conflict resolution. Brain volumes were obtained using MRI. Falls risk was assessed using the Physiological Profile Assessment (PPA). After accounting for baseline age, experimental group, baseline PPA score, and total baseline white matter brain volume, baseline activation in the left frontal orbital cortex extending towards the insula was negatively associated with reduced physiological falls risk over the 12-month period. In contrast, baseline activation in the paracingulate gyrus extending towards the anterior cingulate gyrus was positively associated with reduced physiological falls risk. Baseline activation levels of brain regions underlying response inhibition and selective attention were independently associated with reduced physiological falls risk. This suggests that falls prevention strategies may be facilitated by incorporating intervention components - such as aerobic exercise - that are specifically designed to induce neurocognitive plasticity. ClinicalTrials.gov Identifier: NCT00426881.
Hormonal regulation of alveolarization: structure-function correlation
Directory of Open Access Journals (Sweden)
Godinez Marye H
2006-03-01
Full Text Available Abstract Background Dexamethasone (Dex limits and all-trans-retinoic acid (RA promotes alveolarization. While structural changes resulting from such hormonal exposures are known, their functional consequences are unclear. Methods Neonatal rats were treated with Dex and/or RA during the first two weeks of life or were given RA after previous exposure to Dex. Morphology was assessed by light microscopy and radial alveolar counts. Function was evaluated by plethysmography at d13, pressure volume curves at d30, and exercise swim testing and arterial blood gases at both d15 and d30. Results Dex-treated animals had simplified lung architecture without secondary septation. Animals given RA alone had smaller, more numerous alveoli. Concomitant treatment with Dex + RA prevented the Dex-induced changes in septation. While the results of exposure to Dex + RA were sustained, the effects of RA alone were reversed two weeks after treatment was stopped. At d13, Dex-treated animals had increased lung volume, respiratory rate, tidal volume, and minute ventilation. On d15, both RA- and Dex-treated animals had hypercarbia and low arterial pH. By d30, the RA-treated animals resolved this respiratory acidosis, but Dex-treated animals continued to demonstrate blood gas and lung volume abnormalities. Concomitant RA treatment improved respiratory acidosis, but failed to normalize Dex-induced changes in pulmonary function and lung volumes. No differences in exercise tolerance were noted at either d15 or d30. RA treatment after the period of alveolarization also corrected the effects of earlier Dex exposure, but the structural changes due to RA alone were again lost two weeks after treatment. Conclusion We conclude that both RA- and corticosteroid-treatments are associated with respiratory acidosis at d15. While RA alone-induced changes in structure andrespiratory function are reversed, Dex-treated animals continue to demonstrate increased respiratory rate, minute
The time-oriented boundary states and the Lorentzian-spinfoam correlation functions
International Nuclear Information System (INIS)
Bianchi, Eugenio; Ding You
2012-01-01
A time-oriented semiclassical boundary state is introduced to calculate the correlation function in the Lorentzian Engle-Pereira-Rovelli-Livine spinfoam model. The resulting semiclassical correlation function is shown to match with the one in Regge calculus in a proper limit.
DEFF Research Database (Denmark)
Xu, Chunsheng; Zhang, Dongfeng; Tian, Xiaocao
2017-01-01
Although the correlation between cognition and physical function has been well studied in the general population, the genetic and environmental nature of the correlation has been rarely investigated. We conducted a classical twin analysis on cognitive and physical function, including forced...
International Nuclear Information System (INIS)
Jung, J.; Alvarellos, J.E.; Garcia-Gonzalez, P.; Godby, R.W.
2004-01-01
The complex nature of electron-electron correlations is made manifest in the very simple but nontrivial problem of two electrons confined within a sphere. The description of highly nonlocal correlation and self-interaction effects by widely used local and semilocal exchange-correlation energy density functionals is shown to be unsatisfactory in most cases. Even the best such functionals exhibit significant errors in the Kohn-Sham potentials and density profiles
Functional and Anatomic Correlates of Neural Aging in Birds.
Ottinger, Mary Ann
2018-01-01
Avian species show variation in longevity, habitat, physiologic characteristics, and lifetime endocrine patterns. Lifetime reproductive and metabolic function vary. Much is known about the neurobiology of the song system in many altricial birds. Little is known about aging in neural systems in birds. Captive birds often survive beyond the age they would in the wild, providing an opportunity to gain an understanding of the physiologic and neural changes. This paper reviews the available information with the goal of capturing areas of potential investigation into gaps in our understanding of neural aging as reflected in physiologic, endocrine, and cognitive aging. Copyright © 2017 Elsevier Inc. All rights reserved.
Correlation between videogame mechanics and executive functions through EEG analysis.
Mondéjar, Tania; Hervás, Ramón; Johnson, Esperanza; Gutierrez, Carlos; Latorre, José Miguel
2016-10-01
This paper addresses a different point of view of videogames, specifically serious games for health. This paper contributes to that area with a multidisciplinary perspective focus on neurosciences and computation. The experiment population has been pre-adolescents between the ages of 8 and 12 without any cognitive issues. The experiment consisted in users playing videogames as well as performing traditional psychological assessments; during these tasks the frontal brain activity was evaluated. The main goal was to analyse how the frontal lobe of the brain (executive function) works in terms of prominent cognitive skills during five types of game mechanics widely used in commercial videogames. The analysis was made by collecting brain signals during the two phases of the experiment, where the signals were analysed with an electroencephalogram neuroheadset. The validated hypotheses were whether videogames can develop executive functioning and if it was possible to identify which kind of cognitive skills are developed during each kind of typical videogame mechanic. The results contribute to the design of serious games for health purposes on a conceptual level, particularly in support of the diagnosis and treatment of cognitive-related pathologies. Copyright © 2016 Elsevier Inc. All rights reserved.
Correlation function and electronic spectral line broadening in relativistic plasmas
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Douis S.
2013-01-01
Full Text Available The electrons dynamics and the time autocorrelation function Cee(t for the total electric microfield of the electrons on positive charge impurity embedded in a plasma are considered when the relativistic dynamic of the electrons is taken into account. We have, at first, built the effective potential governing the electrons dynamics. This potential obeys a nonlinear integral equation that we have solved numerically. Regarding the electron broadening of the line in plasma, we have found that when the plasma parameters change, the amplitude of the collision operator changes in the same way as the time integral of Cee(t. The electron-impurity interaction is taken at first time as screened Deutsh interaction and at the second time as Kelbg interaction. Comparisons of all interesting quantities are made with respect to the previous interactions as well as between classical and relativistic dynamics of electrons.
On the zero temperature limit of the Kubo-transformed quantum time correlation function
Hernández de la Peña, Lisandro
2014-04-01
The zero temperature limit of several quantum time correlation functions is analysed. It is shown that while the canonical quantum time correlation function retains the full dynamical information as temperature approaches zero, the Kubo-transformed and the thermally symmetrised quantum time correlation functions lose all dynamical information at this limit. This is shown to be a consequence of the projection onto the ground state, via the limiting process of the quantities ? and ?, either together as a product, or separately. Although these findings would seem to suggest that finite-temperature methods commonly used to estimate Kubo correlation functions would be incapable of retaining any ground state dynamics, we propose a route for recovering in principle all dynamical information at the ground state. It is first shown that the usual frequency space relation between canonical and Kubo correlation functions also holds for microcanonical time correlation functions. Since the Kubo-transformed microcanonical correlation function can be obtained from the usual finite-temperature function by including a projection onto the corresponding microcanonical ensemble, finite-temperature methods, properly modified to incorporate such a constraint, can be used to capture full quantum dynamics at any arbitrary energy state, including the ground state. This approach is illustrated with the application of centroid dynamics to the ground state dynamics of the harmonic oscillator.
Socioeconomic status and cognitive functioning: moving from correlation to causation.
Duncan, Greg J; Magnuson, Katherine
2012-05-01
A growing body of cognitive research uses sophisticated behavioral and neuroimaging measurements to demonstrate associations between family socioeconomic status (SES) and specific cognitive functions. We argue for the value in these kinds of studies of increased sophistication in the measurement and modeling of SES. With regard to measurement, SES combines several components, each of which represents distinct resources that might benefit children's cognitive development in different ways. Policy implications of studies using omnibus SES composites are problematic because there are no 'treatments' for enhancing overall SES, although policies abound for enhancing specific components of SES such as family income. Past literature offers guidance regarding how best to measure each of the SES components. With regard to modeling, we point out that the manipulability of economic, educational, and occupational components of SES varies, which provides opportunities for generating experimental or quasi-experimental variation in some components but not others. Evidence on the causal connections between SES components and child outcomes is summarized. Both experimental and quasi-experimental studies involving manipulation of family income have demonstrated consistent associations with a number of cognitive measures. Quasi-experimental increases in maternal education have also shown associations with child achievement. We end with a discussion of useful directions in SES-related cognitive research. WIREs Cogn Sci 2012, 3:377-386. doi: 10.1002/wcs.1176 For further resources related to this article, please visit the WIREs website. Copyright © 2012 John Wiley & Sons, Ltd.
Nonlinearity of the forward-backward correlation function in the model with string fusion
Vechernin, Vladimir
2017-12-01
The behavior of the forward-backward correlation functions and the corresponding correlation coefficients between multiplicities and transverse momenta of particles produced in high energy hadronic interactions is analyzed by analytical and MC calculations in the models with and without string fusion. The string fusion is taking into account in simplified form by introducing the lattice in the transverse plane. The results obtained with two alternative definitions of the forward-backward correlation coefficient are compared. It is shown that the nonlinearity of correlation functions increases with the width of observation windows, leading at small string density to a strong dependence of correlation coefficient value on the definition. The results of the modeling enable qualitatively to explain the experimentally observed features in the behavior of the correlation functions between multiplicities and mean transverse momenta at small and large multiplicities.
Correlations between motor and sensory functions in upper limb chronic hemiparetics after stroke
Directory of Open Access Journals (Sweden)
Thais Botossi Scalha
2011-08-01
Full Text Available OBJECTIVE: Describe the somatosensory function of the affected upper limb of hemiparetic stroke patients and investigate the correlations between measurements of motor and sensory functions in tasks with and without visual deprivation. METHOD: We applied the Fugl-Meyer Assessment (FMA, Nottingham Sensory Assessment (NSA, and several motor and sensory tests: Paper manipulation (PM, Motor Sequences (MS, Reaching and grasping (RG Tests Functional (TF, Tactile Discrimination (TD, Weight Discrimination (WD and Tactile Recognition of Objects (RO. RESULTS: We found moderate correlations between the FMA motor subscale and the tactile sensation score of the NSA. Additionally, the FMA sensitivity was correlated with the NSA total; and performance on the WD test items correlated with the NSA. CONCLUSION: There was a correlation between the sensory and motor functions of the upper limb in chronic hemiparetic stroke patients. Additionally, there was a greater reliance on visual information to compensate for lost sensory-motor skills.
Correlation between functional disability and quality of life in patients with adhesive capsulitis
Fernandes, Marcos Rassi
2015-01-01
OBJECTIVE: To determine the correlation between functional disability and quality of life of patients with adhesive capsulitis. METHODS: Two instruments (WHOQOL-BREF and DASH) were applied to evaluate the quality of life and functional capacity of patients with adhesive capsulitis. Inclusion criteria were age between 35 and 75 years old and achievement of shoulder imaging. Each domain of the WHOQOL-BREF was correlated with DASH. Pearson's correlation coefficient was used for parametric variables and Spearman's correlation coefficient was used when at least one variable had a non-normal distribution. The level of significance was p adhesive capsulitis. Level of Evidence IV, Prospective Study. PMID:27069405
Brunherotti, Marisa Afonso; Sobreira, Claudia; Rodrigues-Júnior, Antônio Luiz; de Assis, Marcos Renato; Terra Filho, João; Baddini Martinez, José Antônio
2007-01-01
This study investigated the correlations obtained by using the Egen Klassifikation (EK) and Barthel Index (BI) functional scales and respiratory function parameters in patients with Duchenne muscular dystrophy. Spirometry, maximal respiratory pressures, and arterial blood gases were analyzed and graded according to the EK and BI scales in 26 patients. They were classified as high or low risk for introduction of noninvasive ventilation according to the respiratory function. The EK and BI scales significantly correlated with forced vital capacity, forced expiratory volume in 1 second, and maximal respiratory pressures. The worse the functional performance, the worse the respiratory measurements. The degree of correlation between the functional scales and each respiratory parameter was similar. An EK of 21 or higher predicted high risk for the introduction of noninvasive ventilation. EK and BI scales similarly correlated with the degree of respiratory involvement in Duchenne muscular dystrophy. The EK scale was superior in detecting subjects with a higher risk for introduction of noninvasive ventilation.
The correlation functions for the clustering of galaxies and Abell clusters
International Nuclear Information System (INIS)
Jones, B.J.T.; Jones, J.E.; Copenhagen Univ.
1985-01-01
The difference in amplitudes between the galaxy-galaxy correlation function and the correlation function between Abell clusters is a consequence of two facts. Firstly, most Abell clusters with z<0.08 lie in a relatively small volume of the sampled space, and secondly, the fraction of galaxies lying in Abell clusters differs considerably inside and outside of this volume. (The Abell clusters are confined to a smaller volume of space than are the galaxies.) We discuss the implications of this interpretation of the clustering correlation functions and present a simple model showing how such a situation may arise quite naturally in standard theories for galaxy formation. (orig.)
Correlation functions of the energy-momentum tensor in SU(2) gauge theory at finite temperature
DEFF Research Database (Denmark)
Huebner, K.; Karsch, F.; Pica, Claudio
2008-01-01
We calculate correlation functions of the energy-momentum tensor in the vicinity of the deconfinement phase transition of (3+1)-dimensional SU(2) gauge theory and discuss their critical behavior in the vicinity of the second order deconfinement transition. We show that correlation functions...... of the trace of the energy momentum tensor diverge uniformly at the critical point in proportion to the specific heat singularity. Correlation functions of the pressure, on the other hand, stay finite at the critical point. We discuss the consequences of these findings for the analysis of transport...
The Functional Architecture of Noise Correlation in fMRI Responses from Human Visual Cortex
Directory of Open Access Journals (Sweden)
Jungwon Ryu
2011-05-01
Full Text Available When an identical stimulus is presented repeatedly, the activity of sensory cortical neurons varies from trial to trial, dubbed ‘neuronal noise’. Recent electrophysiological and imaging studies reported that the ‘noise’ is not just a random and independent deviation from signal and reflects correlated activity among local cortical sites. Here we investigated the structure of correlated ‘noises’ in early human visual areas by monitoring moment-to-moment fluctuations in fMRI responses to visual stimuli. By defining receptive fields and stimulus preferences of individual voxels, we could reveal a reliable functional architecture of noise correlation: noise correlation was high in pairs of voxels whose stimulus preferences are similar and whose receptive fields are close to each other. The analysis of residual correlation confirmed that this functionally defined structure of noise correlation could not be explained by trivial correlations due to anatomical proximity. The spectral analysis of time series revealed that the stimulus-preference-dependent correlation was maximal at a low (<0.035Hz band of temporal frequency whereas the receptive field-dependent correlation was maximal at a medium (0.035∼0.082Hz band. Furthermore, the functional structure of noise correlation was held true for voxel pairs within and between different visual areas, regardless of the presence or types of visual stimulation.
Directory of Open Access Journals (Sweden)
Vindy Margaretha
2017-06-01
Full Text Available Background: Cerebral Palsy (CP is a group of movement and posture disorder commonly accompanied by comorbidities such as sensation, cognition, communication abnormalities and many more. This study aimed to identify the correlation between gross motor function(measured by Gross Motor Function Classification System, GMFCS and communication function (measured by Communication Function Classification System, CFCS in children with CP. Methods: Thirty six children with CP aged 0–12 years were examined. Samples were taken from Department of Physical Medicine and Rehabilitation Dr. Hasan Sadikin General Hospital Bandung on September to October 2015. Patients’ descriptive data, levels of GMFCS and CFCS were collected by the researcher and residents previously standardized. Kendall’s tau b correlation coefficient was used to analyze the inter-relationship between the GMFCS and CFCS. Results: Levels of GMFCS and CFCS in all samples were moderately correlated (r=0.405; p=0.004. In patients with spastic quadripledic type, correlation were found moderate(r=0.495; p=0.014. No significant correlation was found when CP spastic quadriplegic patients were excluded (r=0.048, p=0.829. Conclusions: Levels of GMFCS and CFCS should be described to provide the complete gross motor and communication picture of CP children.Gross motor function in a child with spastic quadriplegic CP might be correctly predicted from his/ her communication function and vice versa. DOI: 10.15850/amj.v4n2.1092
Neuwald, Andrew F
2016-06-01
The availability of vast amounts of protein sequence data facilitates detection of subtle statistical correlations due to imposed structural and functional constraints. Recent breakthroughs using Direct Coupling Analysis (DCA) and related approaches have tapped into correlations believed to be due to compensatory mutations. This has yielded some remarkable results, including substantially improved prediction of protein intra- and inter-domain 3D contacts, of membrane and globular protein structures, of substrate binding sites, and of protein conformational heterogeneity. A complementary approach is Bayesian Partitioning with Pattern Selection (BPPS), which partitions related proteins into hierarchically-arranged subgroups based on correlated residue patterns. These correlated patterns are presumably due to structural and functional constraints associated with evolutionary divergence rather than to compensatory mutations. Hence joint application of DCA- and BPPS-based approaches should help sort out the structural and functional constraints contributing to sequence correlations. Copyright © 2016 Elsevier Ltd. All rights reserved.
Han, Jeong-Hwan; Oda, Takuji
2018-04-01
The performance of exchange-correlation functionals in density-functional theory (DFT) calculations for liquid metal has not been sufficiently examined. In the present study, benchmark tests of Perdew-Burke-Ernzerhof (PBE), Armiento-Mattsson 2005 (AM05), PBE re-parameterized for solids, and local density approximation (LDA) functionals are conducted for liquid sodium. The pair correlation function, equilibrium atomic volume, bulk modulus, and relative enthalpy are evaluated at 600 K and 1000 K. Compared with the available experimental data, the errors range from -11.2% to 0.0% for the atomic volume, from -5.2% to 22.0% for the bulk modulus, and from -3.5% to 2.5% for the relative enthalpy depending on the DFT functional. The generalized gradient approximation functionals are superior to the LDA functional, and the PBE and AM05 functionals exhibit the best performance. In addition, we assess whether the error tendency in liquid simulations is comparable to that in solid simulations, which would suggest that the atomic volume and relative enthalpy performances are comparable between solid and liquid states but that the bulk modulus performance is not. These benchmark test results indicate that the results of liquid simulations are significantly dependent on the exchange-correlation functional and that the DFT functional performance in solid simulations can be used to roughly estimate the performance in liquid simulations.
International Nuclear Information System (INIS)
Yamanaka, Shusuke; Takeda, Ryo; Nakata, Kazuto; Takada, Toshikazu; Shoji, Mitsuo; Kitagawa, Yasutaka; Yamaguchi, Kizashi
2007-01-01
We present a simple quantum correction scheme for ab initio Kohn-Sham spin density functional theory (KS-SDFT). This scheme is based on a mapping from ab initio results to a Heisenberg model Hamiltonian. The effective exchange integral is estimated by using energies and spin correlation functionals calculated by ab initio KS-SDFT. The quantum-corrected spin-correlation functional is open to be designed to cover specific quantum spin fluctuations. In this article, we present a simple correction for dinuclear compounds having multiple bonds. The computational results are discussed in relation to multireference (MR) DFT, by which we treat the quantum many-body effects explicitly
Scargle, Jeffrey D.
1989-01-01
This paper develops techniques to evaluate the discrete Fourier transform (DFT), the autocorrelation function (ACF), and the cross-correlation function (CCF) of time series which are not evenly sampled. The series may consist of quantized point data (e.g., yes/no processes such as photon arrival). The DFT, which can be inverted to recover the original data and the sampling, is used to compute correlation functions by means of a procedure which is effectively, but not explicitly, an interpolation. The CCF can be computed for two time series not even sampled at the same set of times. Techniques for removing the distortion of the correlation functions caused by the sampling, determining the value of a constant component to the data, and treating unequally weighted data are also discussed. FORTRAN code for the Fourier transform algorithm and numerical examples of the techniques are given.
Four-point correlation function of stress-energy tensors in N=4 superconformal theories
Korchemsky, G P
2015-01-01
We derive the explicit expression for the four-point correlation function of stress-energy tensors in four-dimensional N=4 superconformal theory. We show that it has a remarkably simple and suggestive form allowing us to predict a large class of four-point correlation functions involving the stress-energy tensor and other conserved currents. We then apply the obtained results on the correlation functions to computing the energy-energy correlations, which measure the flow of energy in the final states created from the vacuum by a source. We demonstrate that they are given by a universal function independent of the choice of the source. Our analysis relies only on N=4 superconformal symmetry and does not use the dynamics of the theory.
Correlation functions of the chiral stress-tensor multiplet in $ \\mathcal{N}=4 $ SYM
Chicherin, Dmitry; Eden, Burkhard; Heslop, Paul; Korchemsky, Gregory P.; Mason, Lionel; Sokatchev, Emery
2015-01-01
We give a new method for computing the correlation functions of the chiral part of the stress-tensor supermultiplet that relies on the reformulation of N=4 SYM in twistor space. It yields the correlation functions in the Born approximation as a sum of Feynman diagrams on twistor space that involve only propagators and no integration vertices. We use this unusual feature of the twistor Feynman rules to compute the correlation functions in terms of simple building blocks which we identify as a new class of N=4 off-shell superconformal invariants. Making use of the duality between correlation functions and planar scattering amplitudes, we demonstrate that these invariants represent an off-shell generalisation of the on-shell invariants defining tree-level scattering amplitudes in N=4 SYM.
Correlation functions of the chiral stress-tensor multiplet in N=4 SYM
Energy Technology Data Exchange (ETDEWEB)
Chicherin, Dmitry [LAPTH (Laboratoire d’Annecy-le-Vieux de Physique Théorique, UMR 5108),Université de Savoie, CNRS, B.P. 110, F-74941 Annecy-le-Vieux (France); Doobary, Reza [Science Laboratories, Mathematics Department, Durham University, South Rd, Durham DH1 3LE (United Kingdom); Eden, Burkhard [Institut für Mathematik und Physik, Humboldt-Universität,Zum großen Windkanal 6, 12489 Berlin (Germany); Heslop, Paul [Science Laboratories, Mathematics Department, Durham University, South Rd, Durham DH1 3LE (United Kingdom); Korchemsky, Gregory P. [Institut de Physique Théorique, Unité Mixte de Recherche du CNRS, UMR 3681,CEA Saclay, 91191 Gif-sur-Yvette Cedex (France); Mason, Lionel [Mathematics Department, Oxford University,Woodstock Road, OX2 6GG (United Kingdom); Sokatchev, Emery [LAPTH (Laboratoire d’Annecy-le-Vieux de Physique Théorique, UMR 5108),Université de Savoie, CNRS, B.P. 110, F-74941 Annecy-le-Vieux (France); Physics Department, Theory Unit, CERN,CH -1211, Geneva 23 (Switzerland); Institut Universitaire de France,103, bd Saint-Michel F-75005 Paris (France)
2015-06-29
We give a new method for computing the correlation functions of the chiral part of the stress-tensor supermultiplet that relies on the reformulation of N=4 SYM in twistor space. It yields the correlation functions in the Born approximation as a sum of Feynman diagrams on twistor space that involve only propagators and no integration vertices. We use this unusual feature of the twistor Feynman rules to compute the correlation functions in terms of simple building blocks which we identify as a new class of N=4 off-shell superconformal invariants. Making use of the duality between correlation functions and planar scattering amplitudes, we demonstrate that these invariants represent an off-shell generalisation of the on-shell invariants defining tree-level scattering amplitudes in N=4 SYM.
Stacy A. Ruse; Philip D. Harvey; Vicki G. Davis; Alexandra S. Atkins; Kolleen H. Fox; Richard S.E. Keefe
2014-01-01
Introduction: Assessment of functional capacity is an intrinsic part of determining the functional relevance of response to treatment of cognitive impairment in schizophrenia. Existing methods are highly and consistently correlated with performance on neuropsychological tests, but most current assessments of functional capacity are still paper and pencil simulations. We developed a computerized virtual reality assessment that contains all of the components of a shopping trip. Methods: We a...
Şahin, F; Atalay, N Ş; Akkaya, N; Ercidoğan, Ö; Başakçi, B; Kuran, B
2014-02-01
In this study, we aimed to determine whether there is a correlation between the electrodiagnostic findings and the functional status, muscle strength and sensibility in patients with traumatic nerve injury to the wrists. We assessed 50 patients at a mean of 11.6 months (SD 5.85) (range 6-25) after nerve injury. Sensibility was assessed by monofilament testing. Motor function was evaluated by assessing the manual muscle grade of the abductor pollicis brevis and abductor digiti minimi muscles. Function was evaluated by the Sollerman Hand Function Test. The amplitudes of the compound muscle action potential and the sensory nerve action potential were determined by electroneuromyography. While the compound muscle action potential and sensory nerve action potential amplitudes had significant correlation with muscle grade and Semmes Weinstein Monofilament tests, there was no correlation with the functional scores.
Correlation Function Approach for Estimating Thermal Conductivity in Highly Porous Fibrous Materials
Martinez-Garcia, Jorge; Braginsky, Leonid; Shklover, Valery; Lawson, John W.
2011-01-01
Heat transport in highly porous fiber networks is analyzed via two-point correlation functions. Fibers are assumed to be long and thin to allow a large number of crossing points per fiber. The network is characterized by three parameters: the fiber aspect ratio, the porosity and the anisotropy of the structure. We show that the effective thermal conductivity of the system can be estimated from knowledge of the porosity and the correlation lengths of the correlation functions obtained from a fiber structure image. As an application, the effects of the fiber aspect ratio and the network anisotropy on the thermal conductivity is studied.
Adaptive endpoint detection of seismic signal based on auto-correlated function
International Nuclear Information System (INIS)
Fan Wanchun; Shi Ren
2001-01-01
Based on the analysis of auto-correlation function, the notion of the distance between auto-correlation function was quoted, and the characterization of the noise and the signal with noise were discussed by using the distance. Then, the method of auto- adaptable endpoint detection of seismic signal based on auto-correlated similarity was summed up. The steps of implementation and determining of the thresholds were presented in detail. The experimental results that were compared with the methods based on artificial detecting show that this method has higher sensitivity even in a low signal with noise ratio circumstance
Generalized q-deformed correlation functions as spectral functions of hyperbolic geometry
Energy Technology Data Exchange (ETDEWEB)
Bonora, L. [International School for Advanced Studies (SISSA/ISAS), Trieste (Italy); INFN, Sezione di Trieste, Trieste (Italy); Bytsenko, A.A. [Universidade Estadual de Londrina, Departamento de Fisica, Caixa Postal 6001, Londrina, Parana (Brazil); Guimaraes, M.E.X. [Universidade Federal Fluminense, Instituto de Fisica, Niteroi-RJ CEP (Brazil)
2014-08-15
We analyze the role of vertex operator algebra and 2d amplitudes from the point of view of the representation theory of infinite-dimensional Lie algebras, MacMahon and Ruelle functions. By definition p-dimensional MacMahon function, with p ≤ 3, is the generating function of p-dimensional partitions of integers. These functions can be represented as amplitudes of a two-dimensional c = 1 CFT, and, as such, they can be generalized to p > 3. With some abuse of language we call the latter amplitudes generalized MacMahon functions. In this paper we show that generalized p-dimensional MacMahon functions can be rewritten in terms of Ruelle spectral functions, whose spectrum is encoded in the Patterson-Selberg function of three-dimensional hyperbolic geometry. (orig.)
Patra, Abhilash; Jana, Subrata; Samal, Prasanjit
2018-04-01
The construction of meta generalized gradient approximations based on the density matrix expansion (DME) is considered as one of the most accurate techniques to design semilocal exchange energy functionals in two-dimensional density functional formalism. The exchange holes modeled using DME possess unique features that make it a superior entity. Parameterized semilocal exchange energy functionals based on the DME are proposed. The use of different forms of the momentum and flexible parameters is to subsume the non-uniform effects of the density in the newly constructed semilocal functionals. In addition to the exchange functionals, a suitable correlation functional is also constructed by working upon the local correlation functional developed for 2D homogeneous electron gas. The non-local effects are induced into the correlation functional by a parametric form of one of the newly constructed exchange energy functionals. The proposed functionals are applied to the parabolic quantum dots with a varying number of confined electrons and the confinement strength. The results obtained with the aforementioned functionals are quite satisfactory, which indicates why these are suitable for two-dimensional quantum systems.
DEFF Research Database (Denmark)
Lacevic, N.; Starr, F. W.; Schrøder, Thomas
2003-01-01
Relaxation in supercooled liquids above their glass transition and below the onset temperature of "slow" dynamics involves the correlated motion of neighboring particles. This correlated motion results in the appearance of spatially heterogeneous dynamics or "dynamical heterogeneity." Traditional...... two-point time-dependent density correlation functions, while providing information about the transient "caging" of particles on cooling, are unable to provide sufficiently detailed information about correlated motion and dynamical heterogeneity. Here, we study a four-point, time-dependent density......-q behavior of S4(q,t) provides an estimate of the range of correlated particle motion. We find that xi4(t) has a maximum as a function of time t, and that the value of the maximum of xi4(t) increases steadily from less than one particle diameter to a value exceeding nine particle diameters in the temperature...
The role of correlation functions in the theory of optical wave fields
Schouten, H.; Visser, T.D.
2008-01-01
We discuss the fundamental role of correlation functions in optical wave fields. These functions determine important properties such as the spectrum, the state of polarization, and the state of coherence of light. These properties generally change on propagation, even when the field travels through
Gegenfurtner, Andreas; Kok, Ellen M.; van Geel, Koos; de Bruin, Anique B. H.; Sorger, Bettina
2017-01-01
Functional neuroimaging is a useful approach to study the neural correlates of visual perceptual expertise. The purpose of this paper is to review the functional-neuroimaging methods that have been implemented in previous research in this context. First, we will discuss research questions typically addressed in visual expertise research. Second,…
The Geriatric Hand: Correlation of Hand-Muscle Function and Activity Restriction in Elderly
Incel, Nurgul Arinci; Sezgin, Melek; As, Ismet; Cimen, Ozlem Bolgen; Sahin, Gunsah
2009-01-01
On the basis of the importance of hand manipulation in activities of daily living (ADL), deterioration of hand function because of various factors reduces quality and independence of life of the geriatric population. The aim of this study was to identify age-induced changes in manual function and to quantify the correlations between hand-muscle…
Functional Correlates of Cognitive Dysfunction in Multiple Sclerosis: A Multicenter fMRI Study
Rocca, M.A.; Valsasina, P.; Hulst, H.E.; Abdel-Aziz, K.; Enzinger, C.; Gallo, A.; Pareto, D.; Riccitelli, G.; Muhlert, N.; Ciccarelli, O.; Barkhof, F.; Fazekas, F.; Tedeschi, G.; Arevalo, M.J.; Filippi, M.
2014-01-01
In this multicenter study, we applied functional magnetic resonance imaging (fMRI) to define the functional correlates of cognitive dysfunction in patients with multiple sclerosis (MS). fMRI scans during the performance of the N-back task were acquired from 42 right-handed relapsing remitting (RR)
Gegenfurtner, Andreas; Kok, Ellen M; Van Geel, Koos; de Bruin, Anique B H; Sorger, Bettina
2017-01-01
Functional neuroimaging is a useful approach to study the neural correlates of visual perceptual expertise. The purpose of this paper is to review the functional-neuroimaging methods that have been implemented in previous research in this context. First, we will discuss research questions typically
Giesbertz, K.J.H.; van Leeuwen, Robert; von Barth, Ulf
We put forward an approach for the development of a nonlocal density functional by a direct modeling of the shape of exchange-correlation (xc) hole in inhomogeneous systems. The functional is aimed at giving an accurate xc energy and an accurate corresponding xc potential even in difficult
Signed zeros of Gaussian vector fields - density, correlation functions and curvature
Foltin, G
2003-01-01
We calculate correlation functions of the (signed) density of zeros of Gaussian distributed vector fields. We are able to express correlation functions of arbitrary order through the curvature tensor of a certain abstract Riemann Cartan or Riemannian manifold. As an application, we discuss one- and two-point functions. The zeros of a two-dimensional Gaussian vector field model the distribution of topological defects in the high-temperature phase of two-dimensional systems with orientational degrees of freedom, such as superfluid films, thin superconductors and liquid crystals.
International Nuclear Information System (INIS)
Sarmento, E.F.
1980-01-01
Results are found for the correlation dynamic functions (or the correspondent green functions) between any combination including pairs of electronic anel nuclear spin operators in an antiferromagnet semi-infinite media., at low temperature T N . These correlation functions, are used to investigate, at the same time, the properties of surface spin waves in volume and surface. The dispersion relatons of nuclear and electronic spin waves coupled modes, in surface are found, resolving a system of linearized equatons of spin operators a system of linearized equations of spin operators. (author) [pt
Total and Direct Correlation Function Integrals from Molecular Simulation of Binary Systems
DEFF Research Database (Denmark)
Wedberg, Nils Hejle Rasmus Ingemar; O’Connell, John P.; Peters, Günther H.J.
2011-01-01
The possibility for obtaining derivative properties for mixtures from integrals of spatial total and direct correlation functions obtained from molecular dynamics simulations is explored. Theoretically well-supported methods are examined to extend simulation radial distribution functions to long...... are consistent with an excess Helmholtz energy model fitted to available simulations. In addition, simulations of water/methanol and water/t-butanol mixtures have been carried out. The method yields results for partial molar volumes, activity coefficient derivatives, and individual correlation function integrals...
Caso, A.; Arrachea, L.; Lozano, G. S.
2012-08-01
We calculate current-current correlation functions and find an expression for the zero-frequency noise of multiterminal systems driven by harmonically time-dependent voltages within the Keldysh non-equilibrium Green's functions formalism. We also propose a fluctuation-dissipation relation for current-current correlation functions to define an effective temperature. We discuss the behavior of this temperature and compare it with the local temperature determined by a thermometer and with the effective temperature defined from a single-particle fluctuation-dissipation relation. We show that for low frequencies all the definitions of the temperature coincide.
Role of the Pair Correlation Function in the Dynamical Transition Predicted by Mode Coupling Theory.
Nandi, Manoj Kumar; Banerjee, Atreyee; Dasgupta, Chandan; Bhattacharyya, Sarika Maitra
2017-12-29
In a recent study, we have found that for a large number of systems the configurational entropy at the pair level S_{c2}, which is primarily determined by the pair correlation function, vanishes at the dynamical transition temperature T_{c}. Thus, it appears that the information of the transition temperature is embedded in the structure of the liquid. In order to investigate this, we describe the dynamics of the system at the mean field level and, using the concepts of the dynamical density functional theory, show that the dynamical transition temperature depends only on the pair correlation function. Thus, this theory is similar in spirit to the microscopic mode coupling theory (MCT). However, unlike microscopic MCT, which predicts a very high transition temperature, the present theory predicts a transition temperature that is similar to T_{c}. This implies that the information of the dynamical transition temperature is embedded in the pair correlation function.
Role of the Pair Correlation Function in the Dynamical Transition Predicted by Mode Coupling Theory
Nandi, Manoj Kumar; Banerjee, Atreyee; Dasgupta, Chandan; Bhattacharyya, Sarika Maitra
2017-12-01
In a recent study, we have found that for a large number of systems the configurational entropy at the pair level Sc 2, which is primarily determined by the pair correlation function, vanishes at the dynamical transition temperature Tc. Thus, it appears that the information of the transition temperature is embedded in the structure of the liquid. In order to investigate this, we describe the dynamics of the system at the mean field level and, using the concepts of the dynamical density functional theory, show that the dynamical transition temperature depends only on the pair correlation function. Thus, this theory is similar in spirit to the microscopic mode coupling theory (MCT). However, unlike microscopic MCT, which predicts a very high transition temperature, the present theory predicts a transition temperature that is similar to Tc. This implies that the information of the dynamical transition temperature is embedded in the pair correlation function.
Parental reflective functioning and the neural correlates of processing infant affective cues.
Rutherford, Helena J V; Maupin, Angela N; Landi, Nicole; Potenza, Marc N; Mayes, Linda C
2017-10-01
Parental reflective functioning refers to the capacity for a parent to understand their own and their infant's mental states, and how these mental states relate to behavior. Higher levels of parental reflective functioning may be associated with greater sensitivity to infant emotional signals in fostering adaptive and responsive caregiving. We investigated this hypothesis by examining associations between parental reflective functioning and neural correlates of infant face and cry perception using event-related potentials (ERPs) in a sample of recent mothers. We found both early and late ERPs were associated with different components of reflective functioning. These findings suggest that parental reflective functioning may be associated with the neural correlates of infant cue perception and further support the value of enhancing reflective functioning as a mechanism in parenting intervention programs.
Correlation between adolescents low back pain, trunk muscle functions and physical activity
Tuzikaitė, Gintarė
2016-01-01
Correlation Between Adolescents Low Back Pain, Trunk Muscle Functions and Physical Activity The aim of research work: The aim of this study was to evaluate the relationship between adolescents low back pain, trunk muscle functions and physical activity. Tasks of work: 1. To assess and compare the lumbar proprioception in subjects with and without low back pain. 2. To assess and compare the trunk muscle functions in subjects with and without low back pain. 3. To assess and compare the physical...
On the spurious correlations among the ratio data induced by "the Law of Power Function"
Kusakabe, Shinichi
2011-01-01
Most of the statistical data have power functional relationships with the size of the population, and therefore these statistical data fall in the powerfunctional relationships each other. These relations were analyzed through the derivations based on the simple model, and the law underlying these relations was called as "the Law of Power Function". These power functional relationships necessarily cause the spurious correlations in the regression analyses. These analyses cast doubt the basic ...
Chen, Yoa; Yu, Yong; He, Cheng-qi
2015-11-01
To establish correlations between joint proprioception, muscle flexion and extension peak torque, and functional ability in patients with knee osteoarthritis (OA). Fifty-six patients with symptomatic knee OA were recruited in this study. Both proprioceptive acuity and muscle strength were measured using the isomed-2000 isokinetic dynamometer. Proprioceptive acuity was evaluated by establishing the joint motion detection threshold (JMDT). Muscle strength was evaluated by Max torque (Nm) and Max torque/weight (Nm/ kg). Functional ability was assessed by the Western Ontario and McMaster Universities Osteoarthritis Index physical function (WOMAC-PF) questionnaire. Correlational analyses were performed between proprioception, muscle strength, and functional ability. A multiple stepwise regression model was established, with WOMAC-PF as dependent variable and patient age, body mass index (BMI), visual analogue scale (VAS)-score, mean grade for Kellgren-Lawrance of both knees, mean strength for quadriceps and hamstring muscles of both knees, and mean JMDT of both knees as independent variables. Poor proprioception (high JMDT) was negatively correlated with muscle strength (Pproprioception (high JMDT) and joint pain (WOMAC pain score), and between knee proprioception (high JMDT) and joint stiffness (WOMAC stiffness score). Poor proprioception (high JMDT) was correlated with limitation in functional ability (WOMAC physical function score r=0.659, Pproprioception is associated with poor muscle strength and limitation in functional ability. Patients with symptomatic OA of knees commonly endure with moderate to considerable dysfunction, which is associated with poor proprioception (high JMDT) and high VAS-scale score.
Leite Rodrigues, Sérgio; Melo e Silva, César Augusto; Ferreira Amorim, César; Lima, Terezinha; Almeida Ribeiro, Fernanda; de Assis Viegas, Carlos Alberto
2008-01-01
Exercise capacity in COPD patients depends on the degree of airflow obstruction, the severity of the hypoxaemia and skeletal muscle function. Muscle atrophy and weakness are considered systemic consequences of COPD and are associated with reduced exercise capacity. To investigate the correlation between mild hypoxaemia and muscular strength, muscular fatigue and functional capacity in COPD patients. Ten patients enrolled on a PRP at the Hospital Universitário de Brasília - HUB were included in this study. Lung function was evaluated by spirometry and arterial blood gas analysis. Functional evaluation was made using the 6MWT and using isometric contraction of deltoid and quadriceps muscles. There were positive correlations between PaO2, quadriceps strength (r2 = 0.61 and p = 0.007) and PaO2 and the 6MWT (r2 = 0.96, p = 0.001). There were negative correlations between PaO2 and median frequency of quadriceps (r2 = -0.42 and p = 0.04). We observed significant correlation between quadriceps strength and the 6MWT (r2 = 0.67 and p = 0.001). There was negative correlation between median frequency of quadriceps and the 6MWT (r2 = -0.42 and p = 0.04). We did not observe any correlation between PaO2 and strength or median frequency of deltoid muscle. PaO2 has important correlations with muscular function variables. The main negative impact of mild hypoxaemia and precocious limb muscular disability on COPD patients is decreased functional capacity.
Jiang, Fan; Ding, Wei
2010-10-01
A previously published new rotation function has been improved by using a dynamic correlation coefficient as well as two new scoring functions of relative entropy and mean-square-residues to make the rotation function more robust and independent of a specific set of weights for scoring and ranking. The previously described new rotation function calculates the rotation function of molecular replacement by matching the search model directly with the Patterson vector map. The signal-to-noise ratio for the correct match was increased by averaging all the matching peaks. Several matching scores were employed to evaluate the goodness of matching. These matching scores were then combined into a single total score by optimizing a set of weights using the linear regression method. It was found that there exists an optimal set of weights that can be applied to the global rotation search and the correct solution can be ranked in the top 100 or less. However, this set of optimal weights in general is dependent on the search models and the crystal structures with different space groups and cell parameters. In this work, we try to solve this problem by designing a dynamic correlation coefficient. It is shown that the dynamic correlation coefficient works for a variety of space groups and cell parameters in the global search of rotation function. We also introduce two new matching scores: relative entropy and mean-square-residues. Last but not least, we discussed a valid method for the optimization of the adjustable parameters for matching vectors.
Correlation between quadriceps to hamstring ratio and functional outcomes in patellofemoral pain.
Guney, Hande; Yuksel, Inci; Kaya, Defne; Doral, Mahmut Nedim
2016-08-01
The aim of this study was to investigate the correlation between quadriceps to hamstring (Q:H) ratio and the functional outcomes in Patellofemoral Pain (PFP) patients. The study included forty-four women diagnosed with unilateral PFP. Eccentric and concentric quadriceps and hamstring strength were recorded. Conventional Q:H ratio was calculated as the concentric quadriceps to concentric hamstring peak torque (Ratio 1). Functional ratios were calculated as the eccentric quadriceps to concentric hamstring peak torque (Ratio 2) and as the concentric quadriceps to eccentric hamstring torque (Ratio 3). Functional levels of the patients were determined by using Kujala scores, hop test and step test. Pain levels during activities were recorded. The relationship among Ratio 1, Ratio 2 and Ratio 3 with functional outcomes and pain levels were evaluated using Spearman's correlation coefficient test. Eccentric and concentric quadriceps and hamstring strength were lower on involved side than uninvolved side. Ratio 2 correlated stronger with Kujala score (r=0.69) than Ratio 1 (r=0.49) and Ratio 3 (r=0.30). Step test (r=0.35) and hop test (r=0.38) only correlated with Ratio 2. Pain levels correlated more with Ratio 2 (r values ranged between 0.38 and 0.48). Eccentric quadriceps to concentric hamstring ratio was observed more related to the functional outcomes and painful activities in patients with PFP. Cross-sectional study. Copyright © 2016 Elsevier B.V. All rights reserved.
Calculating the n-point correlation function with general and efficient python code
Genier, Fred; Bellis, Matthew
2018-01-01
There are multiple approaches to understanding the evolution of large-scale structure in our universe and with it the role of baryonic matter, dark matter, and dark energy at different points in history. One approach is to calculate the n-point correlation function estimator for galaxy distributions, sometimes choosing a particular type of galaxy, such as luminous red galaxies. The standard way to calculate these estimators is with pair counts (for the 2-point correlation function) and with triplet counts (for the 3-point correlation function). These are O(n2) and O(n3) problems, respectively and with the number of galaxies that will be characterized in future surveys, having efficient and general code will be of increasing importance. Here we show a proof-of-principle approach to the 2-point correlation function that relies on pre-calculating galaxy locations in coarse “voxels”, thereby reducing the total number of necessary calculations. The code is written in python, making it easily accessible and extensible and is open-sourced to the community. Basic results and performance tests using SDSS/BOSS data will be shown and we discuss the application of this approach to the 3-point correlation function.
Yu, Haoyu S; Zhang, Wenjing; Verma, Pragya; He, Xiao; Truhlar, Donald G
2015-05-14
The goal of this work is to develop a gradient approximation to the exchange-correlation functional of Kohn-Sham density functional theory for treating molecular problems with a special emphasis on the prediction of quantities important for homogeneous catalysis and other molecular energetics. Our training and validation of exchange-correlation functionals is organized in terms of databases and subdatabases. The key properties required for homogeneous catalysis are main group bond energies (database MGBE137), transition metal bond energies (database TMBE32), reaction barrier heights (database BH76), and molecular structures (database MS10). We also consider 26 other databases, most of which are subdatabases of a newly extended broad database called Database 2015, which is presented in the present article and in its ESI. Based on the mathematical form of a nonseparable gradient approximation (NGA), as first employed in the N12 functional, we design a new functional by using Database 2015 and by adding smoothness constraints to the optimization of the functional. The resulting functional is called the gradient approximation for molecules, or GAM. The GAM functional gives better results for MGBE137, TMBE32, and BH76 than any available generalized gradient approximation (GGA) or than N12. The GAM functional also gives reasonable results for MS10 with an MUE of 0.018 Å. The GAM functional provides good results both within the training sets and outside the training sets. The convergence tests and the smooth curves of exchange-correlation enhancement factor as a function of the reduced density gradient show that the GAM functional is a smooth functional that should not lead to extra expense or instability in optimizations. NGAs, like GGAs, have the advantage over meta-GGAs and hybrid GGAs of respectively smaller grid-size requirements for integrations and lower costs for extended systems. These computational advantages combined with the relatively high accuracy for all
Source-Free Exchange-Correlation Magnetic Fields in Density Functional Theory.
Sharma, S; Gross, E K U; Sanna, A; Dewhurst, J K
2018-03-13
Spin-dependent exchange-correlation energy functionals in use today depend on the charge density and the magnetization density: E xc [ρ, m]. However, it is also correct to define the functional in terms of the curl of m for physical external fields: E xc [ρ,∇ × m]. The exchange-correlation magnetic field, B xc , then becomes source-free. We study this variation of the theory by uniquely removing the source term from local and generalized gradient approximations to the functional. By doing so, the total Kohn-Sham moments are improved for a wide range of materials for both functionals. Significantly, the moments for the pnictides are now in good agreement with experiment. This source-free method is simple to implement in all existing density functional theory codes.
Pundik, Svetlana; Falchook, Adam D.; McCabe, Jessica; Daly, Janis J.
2014-01-01
Background. Arm spasticity is a challenge in the care of chronic stroke survivors with motor deficits. In order to advance spasticity treatments, a better understanding of the mechanism of spasticity-related neuroplasticity is needed. Objective. To investigate brain function correlates of spasticity in chronic stroke and to identify specific regional functional brain changes related to rehabilitation-induced mitigation of spasticity. Methods. 23 stroke survivors (>6 months) were treated with an arm motor learning and spasticity therapy (5 d/wk for 12 weeks). Outcome measures included Modified Ashworth scale, sensory tests, and functional magnetic resonance imaging (fMRI) for wrist and hand movement. Results. First, at baseline, greater spasticity correlated with poorer motor function (P = 0.001) and greater sensory deficits (P = 0.003). Second, rehabilitation produced improvement in upper limb spasticity and motor function (P spasticity correlated with higher fMRI activation in the ipsilesional thalamus (rho = 0.49, P = 0.03). Fourth, following rehabilitation, greater mitigation of spasticity correlated with enhanced fMRI activation in the contralesional primary motor (r = −0.755, P = 0.003), premotor (r = −0.565, P = 0.04), primary sensory (r = −0.614, P = 0.03), and associative sensory (r = −0.597, P = 0.03) regions while controlling for changes in motor function. Conclusions. Contralesional motor regions may contribute to restoring control of muscle tone in chronic stroke. PMID:25101190
Impairments in precision grip correlate with functional measures in adult hemiplegia.
McDonnell, Michelle N; Hillier, Susan L; Ridding, Michael C; Miles, Timothy S
2006-07-01
Analysis of a precision grip-lift task provides measures to assess functional disability of the hand, but the correlation between these measures and accepted tests of motor function in stroke patients has not been established. Seventeen subacute stroke patients were studied to compare parameters of a precision grip-lift task between the affected and unaffected side, and to correlate them with function. Functional impairment was assessed with the Action Research Arm Test and the Fugl-Meyer assessment, as well as grip strength and maximal finger-tapping speed. The grip force (GF) and load force (LF) were recorded as patients lifted a custom-built manipulandum. All measures were recorded on two separate occasions, at least 1 week apart. There was good reproducibility between testing sessions for the grip-lift and functional measures. The affected hand gripped the manipulandum for longer prior to lift-off than the unaffected hand, and the normal close temporal coupling between the rate of change of GF and LF during the lift was disrupted. These two measures correlated more highly with the ARAT than the FMA and, when combined with measures of grip strength and tapping speed, explained 71% of the variance of the ARAT. The grip-lift task is a sensitive measure of impaired dexterity following stroke and provides measures which correlate well with a commonly applied functional assessment scale. This task may be used clinically to detect changes in the hemiplegic upper limb during rehabilitation and recovery.
Energy Technology Data Exchange (ETDEWEB)
Berryman, J.G.
1987-01-01
A result of Debye, Anderson, and Brumberger (P. Debye, H. R. Anderson, Jr., and H. Brumberger, J. Appl. Phys. 28, 679 (1957)) for isotropic porous media states that the derivative of the two-point spatial correlation at the origin is equal to minus one-quarter of the specific surface area. This result is generalized for nonisotropic media by noting that the angular average of the anisotropic two-point spatial correlation function has the same relationship to the specific surface area.
Pulmonary function tests correlated with thoracic volumes in adolescent idiopathic scoliosis.
Ledonio, Charles Gerald T; Rosenstein, Benjamin E; Johnston, Charles E; Regelmann, Warren E; Nuckley, David J; Polly, David W
2017-01-01
Scoliosis deformity has been linked with deleterious changes in the thoracic cavity that affect pulmonary function. The causal relationship between spinal deformity and pulmonary function has yet to be fully defined. It has been hypothesized that deformity correction improves pulmonary function by restoring both respiratory muscle efficiency and increasing the space available to the lungs. This research aims to correlate pulmonary function and thoracic volume before and after scoliosis correction. Retrospective correlational analysis between thoracic volume modeling from plain x-rays and pulmonary function tests was conducted. Adolescent idiopathic scoliosis patients enrolled in a multicenter database were sorted by pre-operative Total Lung Capacities (TLC) % predicted values from their Pulmonary Function Tests (PFT). Ten patients with the best and ten patients with the worst TLC values were included. Modeled thoracic volume and TLC values were compared before and 2 years after surgery. Scoliosis correction resulted in an increase in the thoracic volume for patients with the worst initial TLCs (11.7%) and those with the best initial TLCs (12.5%). The adolescents with the most severe pulmonary restriction prior to surgery strongly correlated with post-operative change in total lung capacity and thoracic volume (r 2 = 0.839; p Scoliosis correction in adolescents was found to increase thoracic volume and is strongly correlated with improved TLC in cases with severe restrictive pulmonary function, but no correlation was found in cases with normal pulmonary function. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:175-182, 2017. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.
Dong, Jian-Jun; Zheng, Zhen-Yu; Li, Peng
2018-01-01
An unusual correlation function was conjectured by Campostrini et al. [Phys. Rev. E 91, 042123 (2015), 10.1103/PhysRevE.91.042123] for the ground state of a transverse Ising chain with geometrical frustration. Later, we provided a rigorous proof for it and demonstrated its nonlocal nature based on an evaluation of a Toeplitz determinant in the thermodynamic limit [J. Stat. Mech. (2016) 113102, 10.1088/1742-5468/2016/11/113102]. In this paper, we further prove that all the low excited energy states forming the gapless kink phase share the same asymptotic correlation function with the ground state. As a consequence, the thermal correlation function almost remains constant at low temperatures if one assumes a canonical ensemble.
The role of three-gluon correlation functions in the single spin asymmetry
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Beppu Hiroo
2015-01-01
Full Text Available We study the twist-3 three-gluon contribution to the single spin asymmetry in the light-hadron production in pp collision in the framework of the collinear factorization. We derive the corresponding cross section formula in the leading order with respect to the QCD coupling constant. We also present a numerical calculation of the asymmetry at the RHIC energy, using a model for the three-gluon correlation functions suggested by the asymmetry for the D-meson production at RHIC. We found that the asymmetries for the light-hadron and the jet productions are very useful to constrain the magnitude and form of the correlation functions. Since the three-gluon correlation functions shift the asymmetry for all kinds of hadrons in the same direction, it is unlikely that they become a main source of the asymmetry.
Deleus, Filip; Van Hulle, Marc M
2011-04-15
In this paper we describe a method for functional connectivity analysis of fMRI data between given brain regions-of-interest (ROIs). The method relies on nonnegativity constrained- and spatially regularized multiset canonical correlation analysis (CCA), and assigns weights to the fMRI signals of the ROIs so that their representative signals become simultaneously maximally correlated. The different pairwise correlations between the representative signals of the ROIs are combined using the maxvar approach for multiset CCA, which has been shown to be equivalent to the generalized eigenvector formulation of CCA. The eigenvector in the maxvar approach gives an indication of the relative importance of each ROI in obtaining a maximal overall correlation, and hence, can be interpreted as a functional connectivity pattern of the ROIs. The successive canonical correlations define subsequent functional connectivity patterns, in decreasing order of importance. We apply our method on synthetic data and real fMRI data and show its advantages compared to unconstrained CCA and to PCA. Furthermore, since the representative signals for the ROIs are optimized for maximal correlation they are also ideally suited for further effective connectivity analyses, to assess the information flows between the ROIs in the brain. Copyright © 2011 Elsevier B.V. All rights reserved.
Description and reconstruction of the soil pore space using correlation functions
Gerke, K. M.; Karsanina, M. V.; Skvortsova, E. B.
2012-09-01
In this paper a method for the description and reconstruction of the soil pore space using correlation functions has been examined. The reconstruction procedure employed here is the best way of verification of the potential descriptor of the soil pore space. Thin sections representing eight major types of pore space in zonal loamy soils and parent materials of the Russian Plain with pores of different shapes and orientations have been chosen for this study. Comparison based on the morphological analysis of the original pore space images and their correlation function reconstructions obtained using simulated annealing technique indicates that this method of reconstruction adequately describes the isometric soil pore space with isometric dissected, isometric slightly dissected, and rounded pores. The two-point correlation functions calculated with the use of the orthogonal method proved to be different for the examined types of soil pore space; they reflect the soil porosity, specific surface, and pore structure correlations at different lengths. The results of this study allow us to conclude that the description of the soil pore space with the help of correlation functions is a promising approach, but requires more development. Further directions of the development of this method for describing the soil pore space and determining the soil physical processes are outlined.
Sousa, Raquel Ferreira de; Gazzola, Juliana Maria; Ganança, Maurício Malavasi; Paulino, Célia Aparecida
2011-01-01
Vestibular disorders are common among the elderly, mainly resulting in dizziness and imbalance--symptoms which can impact daily routine activities. To study the correlation between body balance and functional capacity and a comparison of risk of falls, actual falls and the functional capacity of the elderly with chronic vestibular dysfunctions. A cross-sectional, clinical and experimental study with 50 senior citizens--60 to 86 years, with chronic peripheral vestibular dysfunction. These participants underwent body balance assessment by the Dynamic Gait Index (DGI) and functional capacity assessment by the Functional Independence Measure (FIM). The data was tested using the Spearman correlation and comparison tests, Mann-Whitney and Kruskal-Wallis, being α=5% (0.05). There was a significant correlation between the total DGI score and all FIM scores, especially the total score (r=0.447; pbalance and functional capacity in elderly patients with peripheral vestibular disorders, that is: the better the balance, the better the individual's functional capacity. In addition, a worse functional capacity increases the individual's risk of falling.
Wangdell, Johanna; Fridén, Jan
2011-06-01
To investigate the correlation between perceived performance in prioritized activities and physical conditions related to grip reconstruction. Retrospective clinical outcome study. Forty-seven individuals with tetraplegia were included in the study. Each participant underwent tendon transfer surgery in the hand between November 2002 and April 2009 and had a complete 1-year follow-up. Functional characteristics and performance data were collected from our database and medical records. Patients' perceived performances in prioritized activities were recorded using the Canadian Occupational Performance Measurement. Preoperative data included age at surgery, time since injury, severity of injury, sensibility and hand dominance. At 1-year follow-up, grip strength, key pinch strength, finger pulp-to-palm distance, distance between thumb and index finger and wrist flexion were measured. Correlation rank coefficient was used to test the possible relationship between physical data and activity performance. There were improvements in both functional factors and in rated performance of prioritized activities after surgery. There was no correlation between performance change and any of the physical functions, the factors known before surgery, or the functional outcome factors. No correlation exists between a single functional outcome parameter and the patients' perceived performance of their prioritized goals in reconstructive hand surgery in tetraplegia.
Energy Technology Data Exchange (ETDEWEB)
Tao, Jianmin [Los Alamos National Laboratory; Perdew, John P [TULANE UNIV; Staroverov, Viktor N [UNIV OF WESTERN ONTARIO; Scuseria, Gustavo E [RICE UNIV
2008-01-01
We construct a nonlocal density functional approximation with full exact exchange, while preserving the constraint-satisfaction approach and justified error cancellations of simpler semilocal functionals. This is achieved by interpolating between different approximations suitable for two extreme regions of the electron density. In a 'normal' region, the exact exchange-correlation hole density around an electron is semilocal because its spatial range is reduced by correlation and because it integrates over a narrow range to -1. These regions are well described by popular semilocal approximations (many of which have been constructed nonempirically), because of proper accuracy for a slowly-varying density or because of error cancellation between exchange and correlation. 'Abnormal' regions, where non locality is unveiled, include those in which exchange can dominate correlation (one-electron, nonuniform high-density, and rapidly-varying limits), and those open subsystems of fluctuating electron number over which the exact exchange-correlation hole integrates to a value greater than -1. Regions between these extremes are described by a hybrid functional mixing exact and semi local exchange energy densities locally (i.e., with a mixing fraction that is a function of position r and a functional of the density). Because our mixing fraction tends to 1 in the high-density limit, we employ full exact exchange according to the rigorous definition of the exchange component of any exchange-correlation energy functional. Use of full exact exchange permits the satisfaction of many exact constraints, but the nonlocality of exchange also requires balanced nonlocality of correlation. We find that this nonlocality can demand at least five empirical parameters (corresponding roughly to the four kinds of abnormal regions). Our local hybrid functional is perhaps the first accurate size-consistent density functional with full exact exchange. It satisfies other known
Correlation function analysis of the COBE differential microwave radiometer sky maps
Energy Technology Data Exchange (ETDEWEB)
Lineweaver, Charles Howe [Univ. of California, Berkeley, CA (United States). Space Sciences Lab.
1994-08-01
The Differential Microwave Radiometer (DMR) aboard the COBE satellite has detected anisotropies in the cosmic microwave background (CMB) radiation. A two-point correlation function analysis which helped lead to this discovery is presented in detail. The results of a correlation function analysis of the two year DMR data set is presented. The first and second year data sets are compared and found to be reasonably consistent. The positive correlation for separation angles less than ~20° is robust to Galactic latitude cuts and is very stable from year to year. The Galactic latitude cut independence of the correlation function is strong evidence that the signal is not Galactic in origin. The statistical significance of the structure seen in the correlation function of the first, second and two year maps is respectively > 9σ, > 10σ and > 18σ above the noise. The noise in the DMR sky maps is correlated at a low level. The structure of the pixel temperature covariance matrix is given. The noise covariance matrix of a DMR sky map is diagonal to an accuracy of better than 1%. For a given sky pixel, the dominant noise covariance occurs with the ring of pixels at an angular separation of 60° due to the 60° separation of the DMR horns. The mean covariance of 60° is 0.45%$+0.18\\atop{-0.14}$ of the mean variance. The noise properties of the DMR maps are thus well approximated by the noise properties of maps made by a single-beam experiment. Previously published DMR results are not significantly affected by correlated noise.
CORRELATION BETWEEN CERVICAL SAGITTAL ALIGNMENT AND FUNCTIONAL CAPACITY IN CERVICAL SPONDYLOSIS
Directory of Open Access Journals (Sweden)
Marcel Machado da Motta
Full Text Available ABSTRACT Objective: To correlate the radiographic parameters of sagittal cervical alignment with quality of life and functional capacity in patients with cervical spondylosis under conservative treatment. Methods: This is an observational and prospective study in patients with cervical spondylosis under conservative treatment and without indication for surgery. The 52 patients included were divided into three groups: axial pain, radiculopathy, and cervical myelopathy. The radiographic parameters considered were cervical lordosis (CL, cervical sagittal vertical axis (CSVA, T1 slope (TS and the discrepancy between TS and CL (TS-CL. Quality of life and functional capacity were evaluated by the Neck Disability Index (NDI questionnaire. Pain was assessed by the Visual Analogue Scale (VAS. The correlation between the radiographic parameters and the clinical scores was evaluated by the Pearson correlations coefficient. Results: There was no difference in cervical radiographic parameters between the three groups. In the total of the sample, the mean value of the CSVA was 17.8o (±8.3o, CL, 22.4° (± 8.8°; TS, 29.3° (±6.6°, and TS-CL, 7.0° (±7.4°. Significant inverse correlation (r= -0.3, p=0.039 was observed between NDI and CL, but there was no significant correlation between CL and VAS. CSVA (p=0.541, TS (p=0.287 and TS-CL (p=0.287 had no significantly correlated with NDI or VAS. Conclusion: Considering patients with cervical spondylosis not candidates for surgery, the only sagittal parameter that correlated with functional capacity was LC. In these patients, the correlation between cervical alignment and quality of life needs to be better characterized.
Directory of Open Access Journals (Sweden)
A.I.Sokolovsky
2006-01-01
Full Text Available A complete theory for investigation of time correlation functions is developed on the basis of the Bogolyubov reduced description method proceeding from his functional hypothesis. The problem of convergence in the theory of nonequilibrium processes and its relation to the non-analytic dependence of basic values of the theory on a small parameter of the perturbation theory are discussed. A natural regularization of integral equations of the theory is proposed. In the framework of a model of slow variables (hydrodynamics of a fluid, kinetics of a gas a generalized perturbation theory without divergencies is constructed corresponding to a partial summation in a usual perturbation theory. Properties of Green functions are discussed on the basis of resolvent formalism for the Liouville operator. A generalized Ernst and Dorfman theory is elaborated allowing to study the peculiarities of correlation and Green functions and to solve the convergence problem in the reduced description method.
Ruse, Stacy A; Harvey, Philip D; Davis, Vicki G; Atkins, Alexandra S; Fox, Kolleen H; Keefe, Richard S E
2014-03-01
Assessment of functional capacity is an intrinsic part of determining the functional relevance of response to treatment of cognitive impairment in schizophrenia. Existing methods are highly and consistently correlated with performance on neuropsychological tests, but most current assessments of functional capacity are still paper and pencil simulations. We developed a computerized virtual reality assessment that contains all of the components of a shopping trip. We administered the Virtual Reality Functional Capacity Assessment Tool (VRFCAT) to 54 healthy controls and to 51 people with schizophrenia to test its feasibility. Dependent variables for the VRFCAT included time to completion and errors on 12 objectives and the number of times that an individual failed to complete an objective. The MATRICS Consensus Cognitive Battery (MCCB) and a standard functional capacity measure, the UCSD Performance-Based Skills Assessment-Brief (UPSA-B) were administered to the patients with schizophrenia. Patients with schizophrenia performed more poorly than healthy controls on 10/11 of the time variables, as well as 2/12 error scores and 2/12 failed objectives. Pearson correlations for 7 of 15 VRFCAT variables with MCCB composite scores were statistically significant. These results provide support for the possibility of computerized functional capacity assessment, but more substantial studies are required.
Analytic methods for the Percus-Yevick hard sphere correlation functions
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D. Henderson
2009-01-01
Full Text Available The Percus-Yevick theory for hard spheres provides simple accurate expressions for the correlation functions that have proven exceptionally useful. A summary of the author's lecture notes concerning three methods of obtaining these functions are presented. These notes are original only in part. However, they contain some helpful steps and simplifications. The purpose of this paper is to make these notes more widely available.
Buehring, B; Siglinsky, E; Krueger, D; Evans, W; Hellerstein, M; Yamada, Y; Binkley, N
2018-03-01
DXA-measured lean mass is often used to assess muscle mass but has limitations. Thus, we compared DXA lean mass with two novel methods-bioelectric impedance spectroscopy and creatine (methyl-d3) dilution. The examined methodologies did not measure lean mass similarly and the correlation with muscle biomarkers/function varied. Muscle function tests predict adverse health outcomes better than lean mass measurement. This may reflect limitations of current mass measurement methods. Newer approaches, e.g., bioelectric impedance spectroscopy (BIS) and creatine (methyl-d3) dilution (D3-C), may more accurately assess muscle mass. We hypothesized that BIS and D3-C measured muscle mass would better correlate with function and bone/muscle biomarkers than DXA measured lean mass. Evaluations of muscle/lean mass, function, and serum biomarkers were obtained in older community-dwelling adults. Mass was assessed by DXA, BIS, and orally administered D3-C. Grip strength, timed up and go, and jump power were examined. Potential muscle/bone serum biomarkers were measured. Mass measurements were compared with functional and serum data using regression analyses; differences between techniques were determined by paired t tests. Mean (SD) age of the 112 (89F/23M) participants was 80.6 (6.0) years. The lean/muscle mass assessments were correlated (.57-.88) but differed (p Lean mass measures were unrelated to the serum biomarkers measured. These three methodologies do not similarly measure muscle/lean mass and should not be viewed as being equivalent. Functional tests assessing maximal muscle strength/power (grip strength and jump power) correlated with all mass measures whereas gait speed was not. None of the selected serum measures correlated with mass. Efforts to optimize muscle mass assessment and identify their relationships with health outcomes are needed.
Core Noise Diagnostics of Turbofan Engine Noise Using Correlation and Coherence Functions
Miles, Jeffrey H.
2009-01-01
Cross-correlation and coherence functions are used to look for periodic acoustic components in turbofan engine combustor time histories, to investigate direct and indirect combustion noise source separation based on signal propagation time delays, and to provide information on combustor acoustics. Using the cross-correlation function, time delays were identified in all cases, clearly indicating the combustor is the source of the noise. In addition, unfiltered and low-pass filtered at 400 Hz signals had a cross-correlation time delay near 90 ms, while the low-pass filtered at less than 400 Hz signals had a cross-correlation time delay longer than 90 ms. Low-pass filtering at frequencies less than 400 Hz partially removes the direct combustion noise signals. The remainder includes the indirect combustion noise signal, which travels more slowly because of the dependence on the entropy convection velocity in the combustor. Source separation of direct and indirect combustion noise is demonstrated by proper use of low-pass filters with the cross-correlation function for a range of operating conditions. The results may lead to a better idea about the acoustics in the combustor and may help develop and validate improved reduced-order physics-based methods for predicting direct and indirect combustion noise.
Spouse selection and environmental effects on spouse correlation in lung function measures.
Knuiman, Matthew W; Divitini, Mark L; Bartholomew, Helen C
2005-01-01
Concordance between spouses may be due to partner selection factors and/or the effects of marriage/environment. The extent to which partner selection factors contribute to spouse concordance has important implications for heritability studies. The aim of this study was to examine the magnitude of spouse correlation in lung function measures and its relationship to duration of marriage. Cross-sectional and longitudinal data collected over the period 1969 to 1995 for 2615 couples from the Busselton Health Study have been analyzed using the program FISHER. Unadjusted correlations were around 0.45 for forced expiratory volume in 1 second (FEV1) and 0.25 for FEV1/FVC (forced vital capacity) and were reduced to 0.05 and 0.10, respectively, after adjustment for age, height, and smoking. No trend with marriage duration was apparent in both cross-sectional and longitudinal analyses but there was a significant downward trend in the correlations with age at marriage. The findings indicate that observed correlations in lung function measures are mostly due to partner selection factors and that partner selection factors have greater influence for couples that marry at younger ages. Family studies that aim to identify and separate genetic from other influences on lung function measures should not regard the mother-father correlation as due to common environment effects.
Fast Computation of the Two-Point Correlation Function in the Age of Big Data
Pellegrino, Andrew; Timlin, John
2018-01-01
We present a new code which quickly computes the two-point correlation function for large sets of astronomical data. This code combines the ease of use of Python with the speed of parallel shared libraries written in C. We include the capability to compute the auto- and cross-correlation statistics, and allow the user to calculate the three-dimensional and angular correlation functions. Additionally, the code automatically divides the user-provided sky masks into contiguous subsamples of similar size, using the HEALPix pixelization scheme, for the purpose of resampling. Errors are computed using jackknife and bootstrap resampling in a way that adds negligible extra runtime, even with many subsamples. We demonstrate comparable speed with other clustering codes, and code accuracy compared to known and analytic results.
Correlation Between Computed Tomography Density and Functional Status of the Thyroid Gland.
Pandey, Vivek; Reis, Martin; Zhou, Yihua
2016-01-01
This study aimed to determine the correlation between thyroid computed tomography (CT) density and thyroid functional status. Thyroid CT densities were determined in patients who had a noncontrast CT of the cervical spine and a recent thyroid-stimulating hormone (TSH) measurement in a cohort of 157 patients. Thyroid CT densities of patients with abnormally low TSH and high TSH were compared to those with normal TSH. A correlation analysis was performed to determine the correlation between TSH levels and CT densities. Both low and high TSH groups demonstrated significantly decreased thyroid CT densities (P thyroid CT densities and TSH levels (r = 0.40; P thyroid CT density and serum TSH levels. A low thyroid CT density indicates abnormal thyroid function.
Adaptive endpoint detection of seismic signal based on auto-correlated function
International Nuclear Information System (INIS)
Fan Wanchun; Shi Ren
2000-01-01
There are certain shortcomings for the endpoint detection by time-waveform envelope and/or by checking the travel table (both labelled as the artificial detection method). Based on the analysis of the auto-correlation function, the notion of the distance between auto-correlation functions was quoted, and the characterizations of the noise and the signal with noise were discussed by using the distance. Then, the method of auto-adaptable endpoint detection of seismic signal based on auto-correlated similarity was summed up. The steps of implementation and determining of the thresholds were presented in detail. The experimental results that were compared with the methods based on artificial detecting show that this method has higher sensitivity even in a low SNR circumstance
Equilibrium properties of a multi-component ionic mixture I. Sum rules for correlation functions
van Wonderen, A.J.; Suttorp, L.G.
1987-01-01
Equilibrium statistical methods are used to derive sum rules for two- and three-particle correlation functions of a multi-component ionic mixture. Some of these rules are general consequences of the electrostatic character of the interaction, whereas others depend on specific thermodynamic
International Nuclear Information System (INIS)
Stelzer, J.; Trebin, H.R.; Longa, L.
1994-08-01
We report NVT and NPT molecular dynamics simulations of a Gay-Berne nematic liquid crystal using generalization of recently proposed algorithm by Toxvaerd [Phys. Rev. E47, 343, 1993]. On the basis of these simulations the Oseen-Zoher-Frank elastic constants K 11 , K 22 and K 33 as well as the surface constants K 13 and K 24 have been calculated within the framework of the direct correlation function approach of Lipkin et al. [J. Chem. Phys. 82, 472 (1985)]. The angular coefficients of the direct pair correlation function, which enter the final formulas, have been determined from the computer simulation data for the pair correlation function of the nematic by combining the Ornstein-Zernike relation and the Wienier-Hopf factorization scheme. The unoriented nematic approximation has been assumed when constructing the reference, isotropic state of Lipkin et al. By an extensive study of the model over a wide range of temperatures, densities and pressures a very detailed information has been provided about elastic behaviour of the Gay-Berne nematic. Interestingly, it is found that the results for the surface elastic constants are qualitatively different than those obtained with the help of analytical approximations for the isotropic, direct pair correlation function. For example, the values of the surface elastic constants are negative and an order of magnitude smaller than the bulk elasticity. (author). 30 refs, 9 figs
Godwin, Christine A; Hunter, Michael A; Bezdek, Matthew A; Lieberman, Gregory; Elkin-Frankston, Seth; Romero, Victoria L; Witkiewitz, Katie; Clark, Vincent P; Schumacher, Eric H
2017-08-01
Individual differences across a variety of cognitive processes are functionally associated with individual differences in intrinsic networks such as the default mode network (DMN). The extent to which these networks correlate or anticorrelate has been associated with performance in a variety of circumstances. Despite the established role of the DMN in mind wandering processes, little research has investigated how large-scale brain networks at rest relate to mind wandering tendencies outside the laboratory. Here we examine the extent to which the DMN, along with the dorsal attention network (DAN) and frontoparietal control network (FPCN) correlate with the tendency to mind wander in daily life. Participants completed the Mind Wandering Questionnaire and a 5-min resting state fMRI scan. In addition, participants completed measures of executive function, fluid intelligence, and creativity. We observed significant positive correlations between trait mind wandering and 1) increased DMN connectivity at rest and 2) increased connectivity between the DMN and FPCN at rest. Lastly, we found significant positive correlations between trait mind wandering and fluid intelligence (Ravens) and creativity (Remote Associates Task). We interpret these findings within the context of current theories of mind wandering and executive function and discuss the possibility that certain instances of mind wandering may not be inherently harmful. Due to the controversial nature of global signal regression (GSReg) in functional connectivity analyses, we performed our analyses with and without GSReg and contrast the results from each set of analyses. Copyright © 2017 Elsevier Ltd. All rights reserved.
Facao, M.; Lopes, A.; Silva, A. L.; Silva, P.
2011-01-01
We propose an undergraduate numerical project for simulating the results of the second-order correlation function as obtained by an intensity interference experiment for two kinds of light, namely bunched light with Gaussian or Lorentzian power density spectrum and antibunched light obtained from single-photon sources. While the algorithm for…
Jastrow correlations in the α cluster model with symmetrized Fermi functions
International Nuclear Information System (INIS)
Hassan, M.Y.M.; Rabie, A.; Ismail, E.H.
1977-11-01
The elastic scattering form factors of electrons on 12 C, 16 0 and 20 Ne nuclei are calculated using wave functions which have realistic asymptotic behaviour and introducing Jastrow correlations. Analysis of the parameters and comparison with experimental data is given
Colour-dressed hexagon tessellations for correlation functions and non-planar corrections
Eden, Burkhard; Jiang, Yunfeng; le Plat, Dennis; Sfondrini, Alessandro
2018-02-01
We continue the study of four-point correlation functions by the hexagon tessellation approach initiated in [38] and [39]. We consider planar tree-level correlation functions in N=4 supersymmetric Yang-Mills theory involving two non-protected operators. We find that, in order to reproduce the field theory result, it is necessary to include SU( N) colour factors in the hexagon formalism; moreover, we find that the hexagon approach as it stands is naturally tailored to the single-trace part of correlation functions, and does not account for multi-trace admixtures. We discuss how to compute correlators involving double-trace operators, as well as more general 1 /N effects; in particular we compute the whole next-to-leading order in the large- N expansion of tree-level BMN two-point functions by tessellating a torus with punctures. Finally, we turn to the issue of "wrapping", Lüscher-like corrections. We show that SU( N) colour-dressing reproduces an earlier empirical rule for incorporating single-magnon wrapping, and we provide a direct interpretation of such wrapping processes in terms of N=2 supersymmetric Feynman diagrams.
A perturbative approach to the redshift space correlation function: beyond the Standard Model
Energy Technology Data Exchange (ETDEWEB)
Bose, Benjamin; Koyama, Kazuya, E-mail: benjamin.bose@port.ac.uk, E-mail: kazuya.koyama@port.ac.uk [Institute of Cosmology and Gravitation, University of Portsmouth, Burnaby Road, Portsmouth, Hampshire, PO1 3FX (United Kingdom)
2017-08-01
We extend our previous redshift space power spectrum code to the redshift space correlation function. Here we focus on the Gaussian Streaming Model (GSM). Again, the code accommodates a wide range of modified gravity and dark energy models. For the non-linear real space correlation function used in the GSM we use the Fourier transform of the RegPT 1-loop matter power spectrum. We compare predictions of the GSM for a Vainshtein screened and Chameleon screened model as well as GR. These predictions are compared to the Fourier transform of the Taruya, Nishimichi and Saito (TNS) redshift space power spectrum model which is fit to N-body data. We find very good agreement between the Fourier transform of the TNS model and the GSM predictions, with ≤ 6% deviations in the first two correlation function multipoles for all models for redshift space separations in 50Mpc h ≤ s ≤ 180Mpc/ h . Excellent agreement is found in the differences between the modified gravity and GR multipole predictions for both approaches to the redshift space correlation function, highlighting their matched ability in picking up deviations from GR. We elucidate the timeliness of such non-standard templates at the dawn of stage-IV surveys and discuss necessary preparations and extensions needed for upcoming high quality data.
A perturbative approach to the redshift space correlation function: beyond the Standard Model
Bose, Benjamin; Koyama, Kazuya
2017-08-01
We extend our previous redshift space power spectrum code to the redshift space correlation function. Here we focus on the Gaussian Streaming Model (GSM). Again, the code accommodates a wide range of modified gravity and dark energy models. For the non-linear real space correlation function used in the GSM we use the Fourier transform of the RegPT 1-loop matter power spectrum. We compare predictions of the GSM for a Vainshtein screened and Chameleon screened model as well as GR. These predictions are compared to the Fourier transform of the Taruya, Nishimichi and Saito (TNS) redshift space power spectrum model which is fit to N-body data. We find very good agreement between the Fourier transform of the TNS model and the GSM predictions, with <= 6% deviations in the first two correlation function multipoles for all models for redshift space separations in 50Mpch <= s <= 180Mpc/h. Excellent agreement is found in the differences between the modified gravity and GR multipole predictions for both approaches to the redshift space correlation function, highlighting their matched ability in picking up deviations from GR. We elucidate the timeliness of such non-standard templates at the dawn of stage-IV surveys and discuss necessary preparations and extensions needed for upcoming high quality data.
Correlation functions of integrable models: A description of the ABACUS algorithm
Caux, J.S.
2009-01-01
Recent developments in the theory of integrable models have provided the means of calculating dynamical correlation functions of some important observables in systems such as Heisenberg spin chains and one-dimensional atomic gases. This article explicitly describes how such calculations are
Roerdink, J.B.T.M.
1982-01-01
It is shown that the cumulant expansion for linear stochastic differential equations, hitherto used to compute one-time averages of the solution process, is also capable of yielding the two-time correlation and probability density functions. The general case with a coefficient matrix, an
System-bath correlation function probed by conventional and time-gated stimulated photon echo
Boeij, Wim P. de; Pshenichnikov, Maxim S.; Wiersma, Douwe A.
1996-01-01
We show how in the framework of the multimode Brownian oscillator model the system-bath correlation function can be derived from conventional and time-gated stimulated photon echo experiments and consideration of the linear optical spectra. Experiments are performed on the infrared dye DTTCI in room
Second-moment sum rules for correlation functions in a classical ionic mixture
Suttorp, L.G.; Ebeling, W.
1992-01-01
The complete set of second-moment sum rules for the correlation functions of arbitrarily high order describing a classical multi-component ionic mixture in equilibrium is derived from the grand-canonical ensemble. The connection of these sum rules with the large-scale behaviour of fluctuations in an
DEFF Research Database (Denmark)
Wellendorff, Jess; Lundgård, Keld Troen; Møgelhøj, Andreas
2012-01-01
A methodology for semiempirical density functional optimization, using regularization and cross-validation methods from machine learning, is developed. We demonstrate that such methods enable well-behaved exchange-correlation approximations in very flexible model spaces, thus avoiding the overfit......A methodology for semiempirical density functional optimization, using regularization and cross-validation methods from machine learning, is developed. We demonstrate that such methods enable well-behaved exchange-correlation approximations in very flexible model spaces, thus avoiding...... the energetics of intramolecular and intermolecular, bulk solid, and surface chemical bonding, and the developed optimization method explicitly handles making the compromise based on the directions in model space favored by different materials properties. The approach is applied to designing the Bayesian error...... estimation functional with van der Waals correlation (BEEF-vdW), a semilocal approximation with an additional nonlocal correlation term. Furthermore, an ensemble of functionals around BEEF-vdW comes out naturally, offering an estimate of the computational error. An extensive assessment on a range of data...
Energy Technology Data Exchange (ETDEWEB)
Clay, Raymond C. [Univ. of Illinois, Urbana, IL (United States); Mcminis, Jeremy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McMahon, Jeffrey M. [Univ. of Illinois, Urbana, IL (United States); Pierleoni, Carlo [Istituto Nazionale di Fisica Nucleare (INFN), L' aquila (Italy). Lab. Nazionali del Gran Sasso (INFN-LNGS); Ceperley, David M. [Univ. of Illinois, Urbana, IL (United States); Morales, Miguel A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
2014-05-01
The ab initio phase diagram of dense hydrogen is very sensitive to errors in the treatment of electronic correlation. Recently, it has been shown that the choice of the density functional has a large effect on the predicted location of both the liquid-liquid phase transition and the solid insulator-to-metal transition in dense hydrogen. To identify the most accurate functional for dense hydrogen applications, we systematically benchmark some of the most commonly used functionals using quantum Monte Carlo. By considering several measures of functional accuracy, we conclude that the van der Waals and hybrid functionals significantly outperform local density approximation and Perdew-Burke-Ernzerhof. We support these conclusions by analyzing the impact of functional choice on structural optimization in the molecular solid, and on the location of the liquid-liquid phase transition.
International Nuclear Information System (INIS)
Fan, Jiang; Wei, Ding
2010-01-01
A previously published new rotation function has been improved by using a dynamic correlation coefficient as well as two new scoring functions of relative entropy and mean-square-residues to make the rotation function more robust and independent of a specific set of weights for scoring and ranking. The previously described new rotation function calculates the rotation function of molecular replacement by matching the search model directly with the Patterson vector map. The signal-to-noise ratio for the correct match was increased by averaging all the matching peaks. Several matching scores were employed to evaluate the goodness of matching. These matching scores were then combined into a single total score by optimizing a set of weights using the linear regression method. It was found that there exists an optimal set of weights that can be applied to the global rotation search and the correct solution can be ranked in the top 100 or less. However, this set of optimal weights in general is dependent on the search models and the crystal structures with different space groups and cell parameters. In this work, we try to solve this problem by designing a dynamic correlation coefficient. It is shown that the dynamic correlation coefficient works for a variety of space groups and cell parameters in the global search of rotation function. We also introduce two new matching scores: relative entropy and mean-square-residues. Last but not least, we discussed a valid method for the optimization of the adjustable parameters for matching vectors. (condensed matter: structure, thermal and mechanical properties)
A Systematic and Meta-analytic Review of Neural Correlates of Functional Outcome in Schizophrenia.
Wojtalik, Jessica A; Smith, Matthew J; Keshavan, Matcheri S; Eack, Shaun M
2017-10-21
Individuals with schizophrenia are burdened with impairments in functional outcome, despite existing interventions. The lack of understanding of the neurobiological correlates supporting adaptive function in the disorder is a significant barrier to developing more effective treatments. This research conducted a systematic and meta-analytic review of all peer-reviewed studies examining brain-functional outcome relationships in schizophrenia. A total of 53 (37 structural and 16 functional) brain imaging studies examining the neural correlates of functional outcome across 1631 individuals with schizophrenia were identified from literature searches in relevant databases occurring between January, 1968 and December, 2016. Study characteristics and results representing brain-functional outcome relationships were systematically extracted, reviewed, and meta-analyzed. Results indicated that better functional outcome was associated with greater fronto-limbic and whole brain volumes, smaller ventricles, and greater activation, especially during social cognitive processing. Thematic observations revealed that the dorsolateral prefrontal cortex, anterior cingulate, posterior cingulate, parahippocampal gyrus, superior temporal sulcus, and cerebellum may have role in functioning. The neural basis of functional outcome and disability is infrequently studied in schizophrenia. While existing evidence is limited and heterogeneous, these findings suggest that the structural and functional integrity of fronto-limbic brain regions is consistently related to functional outcome in individuals with schizophrenia. Further research is needed to understand the mechanisms and directionality of these relationships, and the potential for identifying neural targets to support functional improvement. © The Author 2017. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.
International Nuclear Information System (INIS)
Mannting, F.
1990-01-01
Quantified pulmonary 201-thallium uptake, assessed as pulmonary/myocardial ratios (PM) and body surface area-corrected absolute pulmonary uptake (Pc), was determined from single photon emission computed tomography studies in 22 normal subjects and 46 consecutive patients with coronary artery disease (CAD). By means of equilibrium radionuclide angiography (ERNA), ejection fraction (EF), peak ejection rate (PER) in end-diastolic volume (EDV/sec) and peak filling rate (PFR) in EDV/sec and stroke volume (SV/sec) units, PFR/PER ratio, and time to peak filling rate (TPFR) in milliseconds were computed at rest and during exercise (n = 35). Left ventricular response to exercise was assessed as delta EF, relative delta EF, delta EDV, and delta ESV. In normal subjects the PM ratios showed significant inverse correlation with PER at rest and with EF, PER, and PFRedv during exercise. For the left ventricular response to exercise, delta ESV showed significant correlation with the PM ratios. The body surface area-corrected pulmonary uptake values showed no correlation with any of the variables. In patients with CAD the PM ratios and Pc uptake showed significant inverse correlation with EF, PER, PFRedv and to exercise EF, exercise PER, and exercise PFRedv. For the left ventricular response to exercise, delta EF showed significant inverse correlation with the PM ratios but not with the Pc uptake. Neither in normal subjects nor in patients with CAD did any of the independent diastolic variables show significant correlation with the PM ratios or Pc values. Thus pulmonary thallium uptake is correlated with systolic left ventricular function at rest and during exercise in normal subjects and in patients with CAD but not with diastolic function. In normal subjects delta ESV and in patients with CAD, delta EF showed correlation with pulmonary thallium uptake
Kim, Jeong-A; Jeong, Jeong-Won; Behen, Michael E; Pilli, Vinod K; Luat, Aimee; Chugani, Harry T; Juhász, Csaba
2018-04-01
To evaluate metabolic changes in the ipsi- and contralateral hemisphere in children showing a cognitive profile consistent with early reorganization of cognitive function, we evaluated the regional glucose uptake, interhemispheric metabolic connectivity, and cognitive function in children with unilateral SWS. Interictal 2-deoxy-2[ 18 F]fluoro-D-glucose (FDG)-PET scans of 27 children with unilateral SWS and mild epilepsy and 27 age-matched control (non-SWS children with epilepsy and normal FDG-PET) were compared using statistical parametric mapping (SPM). Regional FDG-PET abnormalities calculated as SPM(t) scores in the SWS group were correlated with cognitive function (IQ) in left- and right-hemispheric subgroups. Interhemispheric metabolic connectivity between homotopic cortical regions was also calculated. Verbal IQ was substantially (≥10 points difference) higher than non-verbal IQ in 61% of the right- and 71% of the left-hemispheric SWS group. FDG SPM(t) scores in the affected hemisphere showed strong positive correlations with IQ in the left-hemispheric, but not in right-hemispheric SWS group in several frontal, parietal, and temporal cortical regions. Significant positive interhemispheric metabolic connectivity, present in controls, was diminished in the SWS group. In addition, the left-hemispheric SWS group showed inverse metabolic interhemispheric correlations in specific parietal, temporal, and occipital regions. FDG SPM(t) scores in the same regions of the right (unaffected) hemisphere showed inverse correlations with IQ. These findings suggest that left-hemispheric lesions in SWS often result in early reorganization of verbal functions while interfering with ("crowding") their non-verbal cognitive abilities. These cognitive changes are associated with specific metabolic abnormalities in the contralateral hemisphere not directly affected by SWS. © 2017 Wiley Periodicals, Inc.
Accurate correlation energies in one-dimensional systems from small system-adapted basis functions
Baker, Thomas E.; Burke, Kieron; White, Steven R.
2018-02-01
We propose a general method for constructing system-dependent basis functions for correlated quantum calculations. Our construction combines features from several traditional approaches: plane waves, localized basis functions, and wavelets. In a one-dimensional mimic of Coulomb systems, it requires only 2-3 basis functions per electron to achieve high accuracy, and reproduces the natural orbitals. We illustrate its effectiveness for molecular energy curves and chains of many one-dimensional atoms. We discuss the promise and challenges for realistic quantum chemical calculations.
Directory of Open Access Journals (Sweden)
Nageshwar Singh
2013-01-01
Full Text Available It is proposed that a macroscopic theory of propagation and scattering of light through random media can be functional for the dye liquid flowing media in the microscopic levels too, with modest approximations. Maxwell’s equation for a random refractive index medium is approximated and solved for the electric field. An analytical expression for the spectral intensity of the field scattered by the refractive index fluctuations inside a medium has been derived which was valid within the first Born approximation. Far field spectral intensity variation of the radiation propagating through the liquid medium is a consequence of variation in correlation function of the refractive index inhomogeneities. The strength of radiation scattered in a particular direction depends on the spatial correlation function of the refractive index fluctuations of the medium. An attempt is made to explain some of the experimentally observed spectral intensity variations, particularly dye emission propagation through liquid flowing medium, in the presence of thermal and flow field.
Large-N correlation functions in ${\\cal N} = 2$ superconformal QCD
Baggio, Marco; Papadodimas, Kyriakos; Vos, Gideon
2017-01-24
We study extremal correlation functions of chiral primary operators in the large-N SU(N) ${\\cal N} = 2$ superconformal QCD theory and present new results based on supersymmetric localization. We discuss extensively the basis-independent data that can be extracted from these correlators using the leading order large-N matrix model free energy given by the four-sphere partition function. Special emphasis is given to single-trace 2- and 3-point functions as well as a new class of observables that are scalars on the conformal manifold. These new observables are particular quadratic combinations of the structure constants of the chiral ring. At weak 't Hooft coupling we present perturbative results that, in principle, can be extended to arbitrarily high order. We obtain closed-form expressions up to the first subleading order. At strong coupling we provide analogous results based on an approximate Wiener-Hopf method.
Harmonic-phase path-integral approximation of thermal quantum correlation functions
Robertson, Christopher; Habershon, Scott
2018-03-01
We present an approximation to the thermal symmetric form of the quantum time-correlation function in the standard position path-integral representation. By transforming to a sum-and-difference position representation and then Taylor-expanding the potential energy surface of the system to second order, the resulting expression provides a harmonic weighting function that approximately recovers the contribution of the phase to the time-correlation function. This method is readily implemented in a Monte Carlo sampling scheme and provides exact results for harmonic potentials (for both linear and non-linear operators) and near-quantitative results for anharmonic systems for low temperatures and times that are likely to be relevant to condensed phase experiments. This article focuses on one-dimensional examples to provide insights into convergence and sampling properties, and we also discuss how this approximation method may be extended to many-dimensional systems.
Averages of ratios of the Riemann zeta-function and correlations of divisor sums
Conrey, Brian; Keating, Jonathan P.
2017-10-01
Nonlinearity has published articles containing a significant number-theoretic component since the journal was first established. We examine one thread, concerning the statistics of the zeros of the Riemann zeta function. We extend this by establishing a connection between the ratios conjecture for the Riemann zeta-function and a conjecture concerning correlations of convolutions of Möbius and divisor functions. Specifically, we prove that the ratios conjecture and an arithmetic correlations conjecture imply the same result. This provides new support for the ratios conjecture, which previously had been motivated by analogy with formulae in random matrix theory and by a heuristic recipe. Our main theorem generalises a recent calculation pertaining to the special case of two-over-two ratios.
Reduced Rank Mixed Effects Models for Spatially Correlated Hierarchical Functional Data
Zhou, Lan
2010-03-01
Hierarchical functional data are widely seen in complex studies where sub-units are nested within units, which in turn are nested within treatment groups. We propose a general framework of functional mixed effects model for such data: within unit and within sub-unit variations are modeled through two separate sets of principal components; the sub-unit level functions are allowed to be correlated. Penalized splines are used to model both the mean functions and the principal components functions, where roughness penalties are used to regularize the spline fit. An EM algorithm is developed to fit the model, while the specific covariance structure of the model is utilized for computational efficiency to avoid storage and inversion of large matrices. Our dimension reduction with principal components provides an effective solution to the difficult tasks of modeling the covariance kernel of a random function and modeling the correlation between functions. The proposed methodology is illustrated using simulations and an empirical data set from a colon carcinogenesis study. Supplemental materials are available online.
Muscle MRI Findings in Childhood/Adult Onset Pompe Disease Correlate with Muscle Function.
Directory of Open Access Journals (Sweden)
Sebastián Figueroa-Bonaparte
Full Text Available Enzyme replacement therapy has shown to be effective for childhood/adult onset Pompe disease (AOPD. The discovery of biomarkers useful for monitoring disease progression is one of the priority research topics in Pompe disease. Muscle MRI could be one possible test but the correlation between muscle MRI and muscle strength and function has been only partially addressed so far.We studied 34 AOPD patients using functional scales (Manual Research Council scale, hand held myometry, 6 minutes walking test, timed to up and go test, time to climb up and down 4 steps, time to walk 10 meters and Motor Function Measure 20 Scale, respiratory tests (Forced Vital Capacity seated and lying, Maximun Inspiratory Pressure and Maximum Expiratory Pressure, daily live activities scales (Activlim and quality of life scales (Short Form-36 and Individualized Neuromuscular Quality of Life questionnaire. We performed a whole body muscle MRI using T1w and 3-point Dixon imaging centered on thighs and lower trunk region.T1w whole body muscle MRI showed a homogeneous pattern of muscle involvement that could also be found in pre-symptomatic individuals. We found a strong correlation between muscle strength, muscle functional scales and the degree of muscle fatty replacement in muscle MRI analyzed using T1w and 3-point Dixon imaging studies. Moreover, muscle MRI detected mild degree of fatty replacement in paraspinal muscles in pre-symptomatic patients.Based on our findings, we consider that muscle MRI correlates with muscle function in patients with AOPD and could be useful for diagnosis and follow-up in pre-symptomatic and symptomatic patients under treatment.Muscle MRI correlates with muscle function in patients with AOPD and could be useful to follow-up patients in daily clinic.
Directory of Open Access Journals (Sweden)
Svetlana Pundik
2014-01-01
Full Text Available Background. Arm spasticity is a challenge in the care of chronic stroke survivors with motor deficits. In order to advance spasticity treatments, a better understanding of the mechanism of spasticity-related neuroplasticity is needed. Objective. To investigate brain function correlates of spasticity in chronic stroke and to identify specific regional functional brain changes related to rehabilitation-induced mitigation of spasticity. Methods. 23 stroke survivors (>6 months were treated with an arm motor learning and spasticity therapy (5 d/wk for 12 weeks. Outcome measures included Modified Ashworth scale, sensory tests, and functional magnetic resonance imaging (fMRI for wrist and hand movement. Results. First, at baseline, greater spasticity correlated with poorer motor function (P=0.001 and greater sensory deficits (P=0.003. Second, rehabilitation produced improvement in upper limb spasticity and motor function (P<0.0001. Third, at baseline, greater spasticity correlated with higher fMRI activation in the ipsilesional thalamus (rho=0.49, P=0.03. Fourth, following rehabilitation, greater mitigation of spasticity correlated with enhanced fMRI activation in the contralesional primary motor (r=-0.755, P=0.003, premotor (r=−0.565, P=0.04, primary sensory (r=−0.614, P=0.03, and associative sensory (r=−0.597, P=0.03 regions while controlling for changes in motor function. Conclusions. Contralesional motor regions may contribute to restoring control of muscle tone in chronic stroke.
International Nuclear Information System (INIS)
Lopes, Agnaldo Jose; Capone, Domenico; Mogami, Roberto; Jansen, Jose Manoel .E mail: phel.lop@uol.com.br; Cunha, Daniel Leme da; Melo, Pedro Lopes de
2007-01-01
Objective: To correlate tomographic findings with pulmonary function parameters in patients with idiopathic pulmonary fibrosis (IPF). Methods: A cross-sectional study was carried out, in which 30 nonsmoking patients with IPF were evaluated. Using a semiquantitative scoring system, the following high-resolution computerized tomography findings were quantified: total interstitial disease (TID), reticular abnormality/honeycombing, and ground-glass opacity (GGO). The functional variables were measured by spirometry, forced oscillation technique (FOT), helium dilution method, as well as the single-breath method of measuring diffusion capacity of the lung for carbon monoxide (DLCO). Results: Of the 30 patients studied, 18 were female, and 12 were male, with a mean age of 70.9 years. We found that TID and reticular abnormality and honeycombing correlated significantly (negative correlations) with the measurements of forced vital capacity (FVC), total lung capacity (TLC), DLCO, and dynamic respiratory compliance were found, as well as that GGO correlated significantly (and positively) with residual volume/TLC. The ratio of forced expiratory flow between 25 and 75% of FVC to FVC (FEF25-75%/FVC) correlated positively with TID, reticular abnormality/honeycombing, and GGO. Conclusion: In IPF patients, the measurements of volume, diffusion, and dynamic compliance are the physiological variables which best reflect the extent of the interstitial disease on HRCT scans. (author)
Energy Technology Data Exchange (ETDEWEB)
Lopes, Agnaldo Jose; Capone, Domenico; Mogami, Roberto; Jansen, Jose Manoel [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). School of Medical Sciences].E mail: phel.lop@uol.com.br; Cunha, Daniel Leme da [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Pedro Ernesto University Hospital. Dept. of Radiology and Diagnostic Imaging; Melo, Pedro Lopes de [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. of Biology
2007-11-15
Objective: To correlate tomographic findings with pulmonary function parameters in patients with idiopathic pulmonary fibrosis (IPF). Methods: A cross-sectional study was carried out, in which 30 nonsmoking patients with IPF were evaluated. Using a semiquantitative scoring system, the following high-resolution computerized tomography findings were quantified: total interstitial disease (TID), reticular abnormality/honeycombing, and ground-glass opacity (GGO). The functional variables were measured by spirometry, forced oscillation technique (FOT), helium dilution method, as well as the single-breath method of measuring diffusion capacity of the lung for carbon monoxide (DLCO). Results: Of the 30 patients studied, 18 were female, and 12 were male, with a mean age of 70.9 years. We found that TID and reticular abnormality and honeycombing correlated significantly (negative correlations) with the measurements of forced vital capacity (FVC), total lung capacity (TLC), DLCO, and dynamic respiratory compliance were found, as well as that GGO correlated significantly (and positively) with residual volume/TLC. The ratio of forced expiratory flow between 25 and 75% of FVC to FVC (FEF25-75%/FVC) correlated positively with TID, reticular abnormality/honeycombing, and GGO. Conclusion: In IPF patients, the measurements of volume, diffusion, and dynamic compliance are the physiological variables which best reflect the extent of the interstitial disease on HRCT scans. (author)
Directory of Open Access Journals (Sweden)
Ryan PD Alexander
2014-06-01
Full Text Available The limbic system is presumed to have a central role in cognitive performance, in particular memory. The purpose of this study was to investigate the relationship between limbic white matter microstructure and neuropsychological function in temporal lobe epilepsy (TLE patients using diffusion tensor imaging (DTI. Twenty-one adult TLE patients, including seven non-lesional (nlTLE and fourteen with unilateral mesial temporal sclerosis (uTLE, were studied with both DTI and hippocampal T2 relaxometry. Correlations were performed between fractional anisotropy (FA of the bilateral fornix and cingulum, hippocampal T2, neuropsychological tests. Positive correlations were observed in the whole group for the left fornix and Processing Speed Index. In contrast, memory tests did not show significant correlations with DTI findings. Subgroup analysis demonstrated an association between the left fornix and Processing Speed in nlTLE but not uTLE. No correlations were observed between hippocampal T2 and test scores in either the TLE group as a whole or after subgroup analysis. Our findings suggest that integrity of the left fornix specifically is an important anatomical correlate of cognitive function in TLE patients, in particular patients with nlTLE.
Franzmeier, Nicolai; Buerger, Katharina; Teipel, Stefan; Stern, Yaakov; Dichgans, Martin; Ewers, Michael
2017-02-01
Cognitive reserve (CR) shows protective effects on cognitive function in older adults. Here, we focused on the effects of CR at the functional network level. We assessed in patients with amnestic mild cognitive impairment (aMCI) whether higher CR moderates the association between low internetwork cross-talk on memory performance. In 2 independent aMCI samples (n = 76 and 93) and healthy controls (HC, n = 36), CR was assessed via years of education and intelligence (IQ). We focused on the anti-correlation between the dorsal attention network (DAN) and an anterior and posterior default mode network (DMN), assessed via sliding time window analysis of resting-state functional magnetic resonance imaging (fMRI). The DMN-DAN anti-correlation was numerically but not significantly lower in aMCI compared to HC. However, in aMCI, lower anterior DMN-DAN anti-correlation was associated with lower memory performance. This association was moderated by CR proxies, where the association between the internetwork anti-correlation and memory performance was alleviated at higher levels of education or IQ. In conclusion, lower DAN-DMN cross-talk is associated with lower memory in aMCI, where such effects are buffered by higher CR. Copyright © 2016 Elsevier Inc. All rights reserved.
Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations.
Directory of Open Access Journals (Sweden)
Andrew F Neuwald
2016-12-01
Full Text Available Over evolutionary time, members of a superfamily of homologous proteins sharing a common structural core diverge into subgroups filling various functional niches. At the sequence level, such divergence appears as correlations that arise from residue patterns distinct to each subgroup. Such a superfamily may be viewed as a population of sequences corresponding to a complex, high-dimensional probability distribution. Here we model this distribution as hierarchical interrelated hidden Markov models (hiHMMs, which describe these sequence correlations implicitly. By characterizing such correlations one may hope to obtain information regarding functionally-relevant properties that have thus far evaded detection. To do so, we infer a hiHMM distribution from sequence data using Bayes' theorem and Markov chain Monte Carlo (MCMC sampling, which is widely recognized as the most effective approach for characterizing a complex, high dimensional distribution. Other routines then map correlated residue patterns to available structures with a view to hypothesis generation. When applied to N-acetyltransferases, this reveals sequence and structural features indicative of functionally important, yet generally unknown biochemical properties. Even for sets of proteins for which nothing is known beyond unannotated sequences and structures, this can lead to helpful insights. We describe, for example, a putative coenzyme-A-induced-fit substrate binding mechanism mediated by arginine residue switching between salt bridge and π-π stacking interactions. A suite of programs implementing this approach is available (psed.igs.umaryland.edu.
Inference of Functionally-Relevant N-acetyltransferase Residues Based on Statistical Correlations.
Neuwald, Andrew F; Altschul, Stephen F
2016-12-01
Over evolutionary time, members of a superfamily of homologous proteins sharing a common structural core diverge into subgroups filling various functional niches. At the sequence level, such divergence appears as correlations that arise from residue patterns distinct to each subgroup. Such a superfamily may be viewed as a population of sequences corresponding to a complex, high-dimensional probability distribution. Here we model this distribution as hierarchical interrelated hidden Markov models (hiHMMs), which describe these sequence correlations implicitly. By characterizing such correlations one may hope to obtain information regarding functionally-relevant properties that have thus far evaded detection. To do so, we infer a hiHMM distribution from sequence data using Bayes' theorem and Markov chain Monte Carlo (MCMC) sampling, which is widely recognized as the most effective approach for characterizing a complex, high dimensional distribution. Other routines then map correlated residue patterns to available structures with a view to hypothesis generation. When applied to N-acetyltransferases, this reveals sequence and structural features indicative of functionally important, yet generally unknown biochemical properties. Even for sets of proteins for which nothing is known beyond unannotated sequences and structures, this can lead to helpful insights. We describe, for example, a putative coenzyme-A-induced-fit substrate binding mechanism mediated by arginine residue switching between salt bridge and π-π stacking interactions. A suite of programs implementing this approach is available (psed.igs.umaryland.edu).
Correlation Between Vision and Cognitive Function in the Elderly: A Cross-Sectional Study.
Spierer, Oriel; Fischer, Naomi; Barak, Adiel; Belkin, Michael
2016-01-01
The correlation between vision and cognition is not fully understood. Visual impairment in the elderly has been associated with impaired cognitive function, dementia, and Alzheimer disease. The aim was to study the correlation between near visual acuity (VA), refraction, and cognitive state in an elderly population.Subjects ≥75 years were enrolled in this cross-sectional study. Refraction and near VA was tested. Cognitive function was evaluated with a version of the mini-mental state examination for the visually impaired (MMSE-blind). The eye with better VA and no cataract or refractive surgery was analyzed.One-hundred ninety subjects (81.6 ± 5.1 years, 69.5% female) were included. Good VA (≤J3) was associated with high MMSE-blind (>17) (OR = 3.18, 95% CI = 1.57-6.43, P = 0.001). This remained significant adjusting for sex, age, and years of education. Wearing reading glasses correlated significantly with high MMSE-blind after adjustment for sex and age (OR = 2.14, 95% CI = 1.16-3.97, P = 0.016), but reached borderline significance after adjustment for education. There was a trend toward correlation between myopia and better MMSE-blind (r = -0.123, P = 0.09, Pearson correlation).Good VA and wearing glasses seem to correlate with better cognitive function. Reading glasses can serve as a protective factor against cognitive deterioration associated with sensory (visual) deprivation in old age. The association between myopia and cognition requires further investigation.
Hurtado, M M; Triviño, M; Arnedo, M; Roldán, G; Tudela, P
2016-12-30
This research explored the relationship between executive functions (working memory and reasoning subtests of the Wechsler Adult Intelligence Scale, Trail Making and Stroop tests, fluency and planning tasks, and Wisconsin Card Sorting Test) and emotional intelligence measured by the Mayer-Salovey-Caruso Emotional Intelligence Test in patients with schizophrenia or borderline personality disorder compared to a control group. As expected, both clinical groups performed worse than the control group in executive functions and emotional intelligence, although the impairment was greater in the borderline personality disorder group. Executive functions significantly correlated with social functioning. Results are discussed in relation to the brain circuits that mediate executive functions and emotional intelligence and the findings obtained with other models of social cognition. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Koelsch, Stefan; Skouras, Stavros; Jentschke, Sebastian
2013-01-01
Studies addressing brain correlates of emotional personality have remained sparse, despite the involvement of emotional personality in health and well-being. This study investigates structural and functional brain correlates of psychological and physiological measures related to emotional personality. Psychological measures included neuroticism, extraversion, and agreeableness scores, as assessed using a standard personality questionnaire. As a physiological measure we used a cardiac amplitude signature, the so-called E κ value (computed from the electrocardiogram) which has previously been related to tender emotionality. Questionnaire scores and E κ values were related to both functional (eigenvector centrality mapping, ECM) and structural (voxel-based morphometry, VBM) neuroimaging data. Functional magnetic resonance imaging (fMRI) data were obtained from 22 individuals (12 females) while listening to music (joy, fear, or neutral music). ECM results showed that agreeableness scores correlated with centrality values in the dorsolateral prefrontal cortex, the anterior cingulate cortex, and the ventral striatum (nucleus accumbens). Individuals with higher E κ values (indexing higher tender emotionality) showed higher centrality values in the subiculum of the right hippocampal formation. Structural MRI data from an independent sample of 59 individuals (34 females) showed that neuroticism scores correlated with volume of the left amygdaloid complex. In addition, individuals with higher E κ showed larger gray matter volume in the same portion of the subiculum in which individuals with higher E κ showed higher centrality values. Our results highlight a role of the amygdala in neuroticism. Moreover, they indicate that a cardiac signature related to emotionality (E κ) correlates with both function (increased network centrality) and structure (grey matter volume) of the subiculum of the hippocampal formation, suggesting a role of the hippocampal formation for
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Stefan Koelsch
Full Text Available Studies addressing brain correlates of emotional personality have remained sparse, despite the involvement of emotional personality in health and well-being. This study investigates structural and functional brain correlates of psychological and physiological measures related to emotional personality. Psychological measures included neuroticism, extraversion, and agreeableness scores, as assessed using a standard personality questionnaire. As a physiological measure we used a cardiac amplitude signature, the so-called E κ value (computed from the electrocardiogram which has previously been related to tender emotionality. Questionnaire scores and E κ values were related to both functional (eigenvector centrality mapping, ECM and structural (voxel-based morphometry, VBM neuroimaging data. Functional magnetic resonance imaging (fMRI data were obtained from 22 individuals (12 females while listening to music (joy, fear, or neutral music. ECM results showed that agreeableness scores correlated with centrality values in the dorsolateral prefrontal cortex, the anterior cingulate cortex, and the ventral striatum (nucleus accumbens. Individuals with higher E κ values (indexing higher tender emotionality showed higher centrality values in the subiculum of the right hippocampal formation. Structural MRI data from an independent sample of 59 individuals (34 females showed that neuroticism scores correlated with volume of the left amygdaloid complex. In addition, individuals with higher E κ showed larger gray matter volume in the same portion of the subiculum in which individuals with higher E κ showed higher centrality values. Our results highlight a role of the amygdala in neuroticism. Moreover, they indicate that a cardiac signature related to emotionality (E κ correlates with both function (increased network centrality and structure (grey matter volume of the subiculum of the hippocampal formation, suggesting a role of the hippocampal formation for
Application of Discrete Cross-Correlation Function for Observational-Comparative Navigation System
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Matuszewski Jan
2017-12-01
Full Text Available The article presents navigation system project operating on the principle scene matching area correlation (SMAC, using a digital camera, an MEMS e-compass sensor and an ultrasonic ranging module. Systems of this type are used as a component of advanced integrated navigation systems in view of its autonomy and capability of localizing aircrafts with high accuracy and precision. Steering and display of information are implemented using a computer application designed in Matlab programming environment. The object’s location is fixed, using discrete cross-correlation function through matching of the registered terrain image to digital orthophotomap.
Kozel, F Andrew; Revell, Letty J; Lorberbaum, Jeffrey P; Shastri, Ananda; Elhai, Jon D; Horner, Michael David; Smith, Adam; Nahas, Ziad; Bohning, Daryl E; George, Mark S
2004-01-01
We hypothesized that specific brain regions would activate during deception, and these areas would correlate with changes in electrodermal activity (EDA). Eight men were asked to find money hidden under various objects. While functional MRI images were acquired and EDA was recorded, the subjects gave both truthful and deceptive answers regarding the money's location. The group analysis revealed significant activation during deception in the orbitofrontal cortex (OFCx) and anterior cingulate (AC), but individual results were not consistent. Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals.
Zheng, Guo; Wang, Jue; Wang, Lin; Zhou, Muchun; Xin, Yu; Song, Minmin
2017-11-15
The general formulae for second-order moments of Schell-model beams with various correlation functions in atmospheric turbulence are derived and validated by the Bessel-Gaussian Schell-model beams and cosine-Gaussian-correlated Schell-model beams. Our finding shows that the second-order moments of partially coherent Schell-model beams are related to the second-order partial derivatives of source spectral degree of coherence at the origin. The formulae we provide are much more convenient to analyze and research propagation problems in turbulence.
Dziekan, Thomas; Weissbach, Carmen; Voigt, Jan; Ebert, Bernd; MacDonald, Rainer; Bahner, Malte L.; Mahler, Marianne; Schirner, Michael; Berliner, Michael; Berliner, Birgitt; Osel, Jens; Osel, Ilka
2011-07-01
Fluorescence imaging using the dye indocyanine green as a contrast agent was investigated in a prospective clinical study for the detection of rheumatoid arthritis. Normalized variances of correlated time series of fluorescence intensities describing the bolus kinetics of the contrast agent in certain regions of interest were analyzed to differentiate healthy from inflamed finger joints. These values are determined using a robust, parameter-free algorithm. We found that the normalized variance of correlation functions improves the differentiation between healthy joints of volunteers and joints with rheumatoid arthritis of patients by about 10% compared to, e.g., ratios of areas under the curves of raw data.
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Lucas Bleicher
Full Text Available Correlated mutation analysis has a long history of interesting applications, mostly in the detection of contact pairs in protein structures. Based on previous observations that, if properly assessed, amino acid correlation data can also provide insights about functional sub-classes in a protein family, we provide a complete framework devoted to this purpose. An amino acid specific correlation measure is proposed, which can be used to build networks summarizing all correlation and anti-correlation patterns in a protein family. These networks can be submitted to community structure detection algorithms, resulting in subsets of correlated amino acids which can be further assessed by specific parameters and procedures that provide insight into the relationship between different communities, the individual importance of community members and the adherence of a given amino acid sequence to a given community. By applying this framework to three protein families with contrasting characteristics (the Fe/Mn-superoxide dismutases, the peroxidase-catalase family and the C-type lysozyme/α-lactalbumin family, we show how our method and the proposed parameters and procedures are related to biological characteristics observed in these protein families, highlighting their potential use in protein characterization and gene annotation.
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Charles M. Giattino
2017-05-01
Full Text Available Each year over 16 million older Americans undergo general anesthesia for surgery, and up to 40% develop postoperative delirium and/or cognitive dysfunction (POCD. Delirium and POCD are each associated with decreased quality of life, early retirement, increased 1-year mortality, and long-term cognitive decline. Multiple investigators have thus suggested that anesthesia and surgery place severe stress on the aging brain, and that patients with less ability to withstand this stress will be at increased risk for developing postoperative delirium and POCD. Delirium and POCD risk are increased in patients with lower preoperative cognitive function, yet preoperative cognitive function is not routinely assessed, and no intraoperative physiological predictors have been found that correlate with lower preoperative cognitive function. Since general anesthesia causes alpha-band (8–12 Hz electroencephalogram (EEG power to decrease occipitally and increase frontally (known as “anteriorization”, and anesthetic-induced frontal alpha power is reduced in older adults, we hypothesized that lower intraoperative frontal alpha power might correlate with lower preoperative cognitive function. Here, we provide evidence that such a correlation exists, suggesting that lower intraoperative frontal alpha power could be used as a physiological marker to identify older adults with lower preoperative cognitive function. Lower intraoperative frontal alpha power could thus be used to target these at-risk patients for possible therapeutic interventions to help prevent postoperative delirium and POCD, or for increased postoperative monitoring and follow-up. More generally, these results suggest that understanding interindividual differences in how the brain responds to anesthetic drugs can be used as a probe of neurocognitive function (and dysfunction, and might be a useful measure of neurocognitive function in older adults.
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Di Luca Monica
2007-05-01
Full Text Available Abstract Background Frontotemporal Lobar Degeneration (FTLD thus recently renamed, refers to a spectrum of heterogeneous conditions. This same heterogeneity of presentation represents the major methodological limit for the correct evaluation of clinical designation and brain functional correlates. At present, no study has investigated clinical clusters due to specific cognitive and behavioural disturbances beyond current clinical criteria. The aim of this study was to identify clinical FTLD presentation, based on cognitive and behavioural profile, and to define their SPECT functional correlations. Methods Ninety-seven FTLD patients entered the study. A clinical evaluation and standardised assessment were preformed, as well as a brain SPECT perfusion imaging study. Latent Profile Analysis on clinical, neuropsychological, and behavioural data was performed. Voxel-basis analysis of SPECT data was computed. Results Three specific clusters were identified and named "pseudomanic behaviour" (LC1, "cognitive" (LC2, and "pseudodepressed behaviour" (LC3 endophenotypes. These endophenotypes showed a comparable hypoperfusion in left temporal lobe, but a specific pattern involving: medial and orbitobasal frontal cortex in LC1, subcortical brain region in LC2, and right dorsolateral frontal cortex and insula in LC3. Conclusion These findings provide evidence that specific functional-cluster symptom relationship can be delineated in FTLD patients by a standardised assessment. The understanding of the different functional correlates of clinical presentations will hopefully lead to the possibility of individuating diagnostic and treatment algorithms.
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Eich, F. G.; Hellgren, Maria
2014-01-01
We investigate fundamental properties of meta-generalized-gradient approximations (meta-GGAs) to the exchange-correlation energy functional, which have an implicit density dependence via the Kohn-Sham kinetic-energy density. To this purpose, we construct the most simple meta-GGA by expressing the local exchange-correlation energy per particle as a function of a fictitious density, which is obtained by inverting the Thomas-Fermi kinetic-energy functional. This simple functional considerably improves the total energy of atoms as compared to the standard local density approximation. The corresponding exchange-correlation potentials are then determined exactly through a solution of the optimized effective potential equation. These potentials support an additional bound state and exhibit a derivative discontinuity at integer particle numbers. We further demonstrate that through the kinetic-energy density any meta-GGA incorporates a derivative discontinuity. However, we also find that for commonly used meta-GGAs the discontinuity is largely underestimated and in some cases even negative
White-matter changes correlate with cognitive functioning in Parkinson's disease
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Rebecca J Theilmann
2013-04-01
Full Text Available Diffusion tensor imaging (DTI findings from emerging studies of cortical white-matter integrity in Parkinson’s disease (PD without dementia are inconclusive. When white-matter changes have been found, their relationship to cognitive functioning in PD has not been carefully investigated. To better characterize changes in tissue diffusivity and to understand their functional significance, the present study conducted DTI in 25 PD patients without dementia and 26 controls of similar ages. An automated tract-based DTI method was used. Fractional anisotropy (FA, mean diffusivity (MD, axial diffusivity (AD, and radial diffusivity (RD were analyzed. Neuropsychological measures of executive functioning (working memory, verbal fluency, cognitive flexibility, inhibitory control and visuospatial ability were then correlated with regions of interest that showed abnormal diffusivity in the PD group. We found widespread reductions in FA and increases in MD in the PD group relative to controls. These changes were predominantly related to an increase in RD. Increased AD in the PD group was limited to specific frontal tracks of the right hemisphere, possibly signifying more significant tissue changes. Motor-symptom severity did not correlate with FA. However, different measures of executive functioning and visuospatial ability correlated with FA in different segments of tracts, which contain fiber pathways to cortical regions that are thought to support specific cognitive processes. The findings suggest that abnormal tissue diffusivity may be sensitive to subtle cognitive changes in PD, some of which may be prognostic of future cognitive decline.
Correlation between upper limb function and oral health impact in stroke survivors.
da Silva, Fernanda C; da Silva, Daniela F T; Mesquita-Ferrari, Raquel A; Fernandes, Kristianne P S; Bussadori, Sandra K
2015-07-01
[Purpose] The aim of the present study was to evaluate the relationship between upper limb impairment and oral health impact in individuals with hemiparesis stemming from a stroke. [Subjects and Methods] The study subjects were conducted with a sample of 27 stroke survivors with complete or partial hemiparesis with brachial or crural predominance. The 14-item short version of the Oral Health Impact Profile was used to evaluate perceptions of oral health. The Brazilian version of the Stroke Specific Quality of Life Scale was used to evaluate perceptions regarding quality of life. [Results] A statistically significant association was found between the upper extremity function subscale of the SSQOL-Brazil and the impact of oral health evaluated using the OHIP-14, with a strong correlation found for the physical pain subscale, moderate correlations with the functional limitation, psychological discomfort, physical disability, social disability and social handicap subscales as well as a weak correlation with the psychological disability subscale. Analyzing the OHIP-14 scores with regard to the impact of oral health on quality of life, the most frequent classification was weak impact, with small rates of moderate and strong impact. [Conclusion] Compromised upper limb function and self-perceived poor oral health, whether due to cultural resignation or functional disability, exert a negative impact on the quality of life of individuals with hemiparesis stemming from a stroke.
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Blair, S.C.; Berge, P.A.; Berryman, J.G.
1993-08-01
We have developed an image-processing method for characterizing the microstructure of rock and other porous materials, and for providing a quantitative means for understanding the dependence of physical properties on the pore structure. This method is based upon the statistical properties of the microgeometry as observed in scanning electron micrograph (SEM) images of cross sections of porous materials. The method utilizes a simple statistical function, called the spatial correlation function, which can be used to predict bounds on permeability and other physical properties. We obtain estimates of the porosity and specific surface area of the material from the two-point correlation function. The specific surface area can be related to the permeability of porous materials using a Kozeny-Carman relation, and we show that the specific surface area measured on images of sandstones is consistent with the specific surface area used in a simple flow model for computation of permeability. In this paper, we discuss the two-point spatial correlation function and its use in characterizing microstructure features such as pore and grain sizes. We present estimates of permeabilities found using SEM images of several different synthetic and natural sandstones. Comparison of the estimates to laboratory measurements shows good agreement. Finally, we briefly discuss extension of this technique to two-phase flow.
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Nathalia Priscilla Oliveira Silva
2014-12-01
Full Text Available Functional independence and quality of life are impacted by amyotrophic lateral sclerosis (ALS, a degenerative and progressive disease. The aim of this study was to investigate the functional independence and quality of life of patients with ALS in the municipality of Natal, Rio Grande do Norte state, Brazil. This is a cross-sectional observational study conducted with 24 patients. The Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40/BR and the Functional Independence Measure (FIM were used as evaluation instruments. The data were analyzed through the Spearman’s correlation and Mann-Whitney tests. The individuals investigated presented modified functional dependence in the FIM, with mean of 64.9±20.5, and alteration in all areas of the ALSAQ-40/ BR. There was significant inverse correlation between FIM and the ALSAQ-40/BR areas of “Mobility” (p<0.01, “Activities of Daily Living (DLAs” (p<0.01, “Eating ability” (p=0.02, and “Communication” (p<0.01, but not in the domain of “Emotional Aspect”. Despite the reduced sample, all patients presented reduction in functional independence and quality of life. The use of these instruments may be a tool to assist the elaboration of intervention plans and interdisciplinary treatment, contributing to retard functional dependence and improve the quality of life of these patients.
Gommes, C. J.; Jiao, Y.; Torquato, S.
2012-05-01
A two-point correlation function provides a crucial yet an incomplete characterization of a microstructure because distinctly different microstructures may have the same correlation function. In an earlier Letter [Gommes, Jiao, and Torquato, Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.108.080601 108, 080601 (2012)], we addressed the microstructural degeneracy question: What is the number of microstructures compatible with a specified correlation function? We computed this degeneracy, i.e., configurational entropy, in the framework of reconstruction methods, which enabled us to map the problem to the determination of ground-state degeneracies. Here, we provide a more comprehensive presentation of the methodology and analyses, as well as additional results. Since the configuration space of a reconstruction problem is a hypercube on which a Hamming distance is defined, we can calculate analytically the energy profile of any reconstruction problem, corresponding to the average energy of all microstructures at a given Hamming distance from a ground state. The steepness of the energy profile is a measure of the roughness of the energy landscape associated with the reconstruction problem, which can be used as a proxy for the ground-state degeneracy. The relationship between this roughness metric and the ground-state degeneracy is calibrated using a Monte Carlo algorithm for determining the ground-state degeneracy of a variety of microstructures, including realizations of hard disks and Poisson point processes at various densities as well as those with known degeneracies (e.g., single disks of various sizes and a particular crystalline microstructure). We show that our results can be expressed in terms of the information content of the two-point correlation functions. From this perspective, the a priori condition for a reconstruction to be accurate is that the information content, expressed in bits, should be comparable to the number of pixels in the unknown
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Maleki
2016-06-01
Full Text Available Background Developmental cordination disorder (DCD is a serious deficit in development of motor coordination, which affects educational achievements and daily life activities to a considerable extent. Objectives The present study aimed to investigate correlations between components of executive function and spelling and math performance of 7 - 11-year-old children with DCD. Materials and Methods A descriptive-analytic study was conducted on 53 primary school children with DCD. Persian version of motor observation questionnaire for teachers (PMOQ-T was used to detect DCD. Executive functions and educational achievements of these children were evaluated using behavior rating inventory of executive function (BRIEF and a researcher-made test, respectively. Results were analyzed through SPSS software (v. 21 and Pearson correlation coefficient. Results The findings showed that components of inhibition (r = -0.27, P < 0.05, working memory (r = -0.44, P < 0.01 and organization of material (r = -0.28, P < 0.05 were significantly correlated with the spelling test. And components of inhibition (r = -0.27, P < 0.05, shift (r = -0.38, P < 0. 01, working memory (r = -0.28, P < 0.05, and planning (r = -.29, P<0.05 were correlated with math test. Conclusions The results may help clinicians for early intervention and focus on related components of executive function to improve the educational performance of DCD children. Knowing that executive function skills are associated with these two achievement domains suggests potentiality of targeted math and spelling interventions for DCD children.
Metabolic correlates of general cognitive function in nondemented elderly subjects: an FDG PET study
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Cho, Sang Soo; Kwak, Young Bin; Lee, Eun Ju; Ryu, Chang Hyung; Chey, Jean Yung; Kim, Sang Eun
2004-01-01
While many studies examined the neural correlates of individual cognitive functions, few made efforts to identify the neural networks associated with general cognitive function. General cognitive function decline in the elderly population is not infrequent. This study examined the brain areas associated with general cognitive function in the elderly subjects. Community-dwelling 116 elderly subjects without dementing illnesses (age, 71±5 y; 13 males and 103 females) participated. General cognitive ability was assessed with the Dementia Rating Scale (K-DRS), which is composed of five subtests of attention, initiation and perseveration, construction, conceptualization, and memory. The EVLT (Elderly Verbal Learning Test), a nine-word list learning test, was used for general memory assessment. Brain FDG PET scans were acquired in all subjects. Brain regions where metabolic levels are correlated with the total scores of K-DRS and EVLT were examined using SPM99. There was a significant positive correlation (P < 0.01 uncorrected, k=100) between the total score of K-DRS and glucose metabolism in the bilateral posterior cingulate gyri, bilateral inferior frontal gyri, left caudate, left inferior parietal lobule, right precuneus, bilateral unci, right parahippocampal gyrus, and right anterior cingulate gyrus. A significant positive correlation between the total score of EVLT and glucose metabolism was shown in the right precuneus, right posterior cingulate gyrus, left insula, bilateral inferior parietal lobules, left anterior cingulate gyrus, left caudate, right inferior frontal gyrus (P < 0.01 uncorrected, k=100). Our data showed the brain regions that are associated with general cognitive function in the elderly. Those regions may serve as the neural substrated of cognitive dysfunction associated with neurodegenerative and cerebrovascular diseases in elderly subjects
Karsanina, M.; Gerke, K.; Vasilyev, R.; Skvortsova, E. B.; Korost, D. V.; Mallants, D.
2013-12-01
It is now well-established that structure of porous or composite media (i.e., distribution of different materials or phases) defines all physical properties, including multi-phase flow and solute transport. To characterize soil structure conventional soil science uses such metrics as grain size distribution, morphology or numerous classifications. However, all these descriptors provide only limited and often qualitative information about structural properties, cannot be used to reconstruct real structure or predict physical properties. With the progress of modern non-destructive analysis tools we can obtain detailed 3D structure information and use it for calculation of any physical property. Such 3D data is a valuable verification dataset to check the usefulness of soil structure description using stochastic measures such as correlation functions. Any potential soil structure descriptor should possess two main features: 1) represent structure in some mathematical way, 2) reconstruction based on this mathematical function alone should be statistically equal to the original structure (e.g., have similar pore size distributions, physical properties, etc.). To check the applicability to soil science, we choose different 2D and 3D segmented soil images and calculated their correlation function. The modified Yeong-Torquato procedure was then used to reconstruct images based on calculated correlation functions. This method was applied to three different soil datasets: 1) a set of 2D thin-sections, 2) 3D images of soils with known hydraulic properties (Ksat and WRC), 3) 3D images of soils and aggregates from the same soil profile, but different genetic horizons. In the first case, we use conventional morphological descriptors in 2D original and reconstructed images (pore size, shapes and orientations) to quantify reconstructions quality. In the second case, we use pore-network models extracted from original and reconstructed 3D images to calculate Ksat, WRC and relative
Logarithmic two-point correlation functions from a z=2 Lifshitz model
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Zingg, T. [Institute for Theoretical Physics and Spinoza Institute, Universiteit Utrecht,Leuvenlaan 4, 3584 CE Utrecht (Netherlands)
2014-01-21
The Einstein-Proca action is known to have asymptotically locally Lifshitz spacetimes as classical solutions. For dynamical exponent z=2, two-point correlation functions for fluctuations around such a geometry are derived analytically. It is found that the retarded correlators are stable in the sense that all quasinormal modes are situated in the lower half-plane of complex frequencies. Correlators in the longitudinal channel exhibit features that are reminiscent of a structure usually obtained in field theories that are logarithmic, i.e. contain an indecomposable but non-diagonalizable highest weight representation. This provides further evidence for conjecturing the model at hand as a candidate for a gravity dual of a logarithmic field theory with anisotropic scaling symmetry.
Modeling fractal structure of city-size distributions using correlation functions.
Chen, Yanguang
2011-01-01
Zipf's law is one the most conspicuous empirical facts for cities, however, there is no convincing explanation for the scaling relation between rank and size and its scaling exponent. Using the idea from general fractals and scaling, I propose a dual competition hypothesis of city development to explain the value intervals and the special value, 1, of the power exponent. Zipf's law and Pareto's law can be mathematically transformed into one another, but represent different processes of urban evolution, respectively. Based on the Pareto distribution, a frequency correlation function can be constructed. By scaling analysis and multifractals spectrum, the parameter interval of Pareto exponent is derived as (0.5, 1]; Based on the Zipf distribution, a size correlation function can be built, and it is opposite to the first one. By the second correlation function and multifractals notion, the Pareto exponent interval is derived as [1, 2). Thus the process of urban evolution falls into two effects: one is the Pareto effect indicating city number increase (external complexity), and the other the Zipf effect indicating city size growth (internal complexity). Because of struggle of the two effects, the scaling exponent varies from 0.5 to 2; but if the two effects reach equilibrium with each other, the scaling exponent approaches 1. A series of mathematical experiments on hierarchical correlation are employed to verify the models and a conclusion can be drawn that if cities in a given region follow Zipf's law, the frequency and size correlations will follow the scaling law. This theory can be generalized to interpret the inverse power-law distributions in various fields of physical and social sciences.
Brain perfusion correlates of cognitive and nigrostriatal functions in de novo Parkinson's disease
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Nobili, Flavio; Arnaldi, Dario; Campus, Claudio; Ferrara, Michela; Brugnolo, Andrea; Dessi, Barbara; Girtler, Nicola; Rodriguez, Guido [University of Genoa, Clinical Neurophysiology, Department of Neurosciences, Ophthalmology and Genetics, Genoa (Italy); De Carli, Fabrizio [National Research Council, Institute of Molecular Bioimaging and Physiology, Genoa (Italy); Morbelli, Silvia; Sambuceti, Gianmario [University of Genoa, Nuclear Medicine, Department of Internal Medicine, Genoa (Italy); Abruzzese, Giovanni [University Hospital San. Martino, Clinical Neurology, Department of Neurosciences, Ophthalmology and Genetics, Genoa (Italy)
2011-12-15
Subtle cognitive impairment is recognized in the first stages of Parkinson's disease (PD), including executive, memory and visuospatial dysfunction, but its pathophysiological basis is still debated. Twenty-six consecutive, drug-naive, de novo PD patients underwent an extended neuropsychological battery, dopamine transporter (DAT) and brain perfusion single photon emission computed tomography (SPECT). We previously reported that nigrocaudate impairment correlates with executive functions, and nigroputaminal impairment with visuospatial abilities. Here perfusion SPECT was first compared between the PD group and age-matched controls (CTR). Then, perfusion SPECT was correlated with both DAT SPECT and four neuropsychological factors by means of voxel-based analysis (SPM8) with a height threshold of p < 0.005 at peak level and p < 0.05 false discovery rate-corrected at cluster level. Both perfusion and DAT SPECT images were flipped in order to have the more affected hemisphere (MAH), defined clinically, on the same side. Significant hypoperfusion was found in an occipital area of the MAH in PD patients as compared to CTR. Executive functions directly correlated with brain perfusion in bilateral posterior cingulate cortex and precuneus in the less affected hemisphere (LAH), while verbal memory directly correlated with perfusion in the precuneus, inferior parietal lobule and superior temporal gyrus in the LAH. Furthermore, positive correlation was highlighted between nigrocaudate and nigroputaminal impairment and brain perfusion in the precuneus, posterior cingulate and parahippocampal gyri of the LAH. These data support the evidence showing an early involvement of the cholinergic system in the early cognitive dysfunction and point to a more relevant role of parietal lobes and posterior cingulate in executive functions in PD. (orig.)
Sumner, Jennifer A; Pietrzak, Robert H; Danielson, Carla Kmett; Adams, Zachary W; Ruggiero, Kenneth J
2014-12-01
The aim of this study was to elucidate the dimensional structure of posttraumatic stress disorder (PTSD) and potential moderators and functional correlates of this structure in disaster-affected adolescents. A population-based sample of 2000 adolescents aged 12-17 years (M = 14.5 years; 51% female) completed interviews on post-tornado PTSD symptoms, substance use, and parent-adolescent conflict between 4 and 13 months (M = 8.8, SD = 2.6) after tornado exposure. Confirmatory factor analyses revealed that all models fit well but a 5-factor dysphoric arousal model provided a statistically significantly better representation of adolescent PTSD symptoms compared to 4-factor dysphoria and emotional numbing models. There was evidence of measurement invariance of the dysphoric arousal model across gender and age, although girls and older adolescents aged 15-17 years had higher mean scores than boys and younger adolescents aged 12-14 years, respectively, on some PTSD dimensions. Differential magnitudes of association between PTSD symptom dimensions and functional correlates were observed, with emotional numbing symptoms most strongly positively associated with problematic substance use since the tornado, and dysphoric arousal symptoms most strongly positively associated with parent-adolescent conflict; both correlations were significantly larger than the corresponding correlations with anxious arousal. Taken together, these results suggest that the dimensional structure of tornado-related PTSD symptomatology in adolescents is optimally characterized by five separate clusters of re-experiencing, avoidance, numbing, dysphoric arousal, and anxious arousal symptoms, which showed unique associations with functional correlates. Findings emphasize that PTSD in disaster-exposed adolescents is not best conceptualized as a homogenous construct and highlight potential differential targets for post-disaster assessment and intervention. Copyright © 2014 Elsevier Ltd. All rights
Brain perfusion correlates of cognitive and nigrostriatal functions in de novo Parkinson's disease
International Nuclear Information System (INIS)
Nobili, Flavio; Arnaldi, Dario; Campus, Claudio; Ferrara, Michela; Brugnolo, Andrea; Dessi, Barbara; Girtler, Nicola; Rodriguez, Guido; De Carli, Fabrizio; Morbelli, Silvia; Sambuceti, Gianmario; Abruzzese, Giovanni
2011-01-01
Subtle cognitive impairment is recognized in the first stages of Parkinson's disease (PD), including executive, memory and visuospatial dysfunction, but its pathophysiological basis is still debated. Twenty-six consecutive, drug-naive, de novo PD patients underwent an extended neuropsychological battery, dopamine transporter (DAT) and brain perfusion single photon emission computed tomography (SPECT). We previously reported that nigrocaudate impairment correlates with executive functions, and nigroputaminal impairment with visuospatial abilities. Here perfusion SPECT was first compared between the PD group and age-matched controls (CTR). Then, perfusion SPECT was correlated with both DAT SPECT and four neuropsychological factors by means of voxel-based analysis (SPM8) with a height threshold of p < 0.005 at peak level and p < 0.05 false discovery rate-corrected at cluster level. Both perfusion and DAT SPECT images were flipped in order to have the more affected hemisphere (MAH), defined clinically, on the same side. Significant hypoperfusion was found in an occipital area of the MAH in PD patients as compared to CTR. Executive functions directly correlated with brain perfusion in bilateral posterior cingulate cortex and precuneus in the less affected hemisphere (LAH), while verbal memory directly correlated with perfusion in the precuneus, inferior parietal lobule and superior temporal gyrus in the LAH. Furthermore, positive correlation was highlighted between nigrocaudate and nigroputaminal impairment and brain perfusion in the precuneus, posterior cingulate and parahippocampal gyri of the LAH. These data support the evidence showing an early involvement of the cholinergic system in the early cognitive dysfunction and point to a more relevant role of parietal lobes and posterior cingulate in executive functions in PD. (orig.)
Kang, Jeong-Il; Jeong, Dae-Keun; Choi, Hyun
2018-01-01
[Purpose] The purpose of this study is to determine the effect that secondary postural deformities and chronic postural abnormalities have on lung capacity, as well as correlate the activity of the respiratory muscles. The results provide basic objective data about the forward head posture and respiratory muscle activity that can be used in clinical situations. [Subjects and Methods] The subjects used in this study were 24 patients aged 25 to 35 years old who visited a hospital in Jeollanam-do Province, Korea, between September 2015 and January 2016. The patients were diagnosed with forward head posture because the vertical line between the acromion process and the external acoustic meatus was at least 5 cm. We measured the craniovertebral angle, pulmonary functions, and respiratory muscle activity of the subjects for correlation analysis. [Results] A positive correlation was found between the craniovertebral angle and the forced vital capacity (r=0.63), while a negative correlation was found between the craniovertebral angle and the sternocleidomastoid muscle (r=-0.77). The craniovertebral angle and the anterior scalene muscle showed a negative correlation (r=-0.65). There were positive correlations between the forced vital capacity and the sternocleidomastoid muscle (r=0.71), and between the forced vital capacity and the anterior scalene muscle (r=0.59). [Conclusion] Severe forward head posture increased the activities of the sternocleidomastoid muscles and the anterior scalene muscles, and decreased the forced vital capacity. Thus, it is necessary to develop more efficient interventions for managing forward head posture based on pulmonary function and the activity of the respiratory synergist muscles.
Probing Real-Space and Time-Resolved Correlation Functions with Many-Body Ramsey Interferometry
Knap, Michael; Kantian, Adrian; Giamarchi, Thierry; Bloch, Immanuel; Lukin, Mikhail D.; Demler, Eugene
2013-10-01
We propose to use Ramsey interferometry and single-site addressability, available in synthetic matter such as cold atoms or trapped ions, to measure real-space and time-resolved spin correlation functions. These correlation functions directly probe the excitations of the system, which makes it possible to characterize the underlying many-body states. Moreover, they contain valuable information about phase transitions where they exhibit scale invariance. We also discuss experimental imperfections and show that a spin-echo protocol can be used to cancel slow fluctuations in the magnetic field. We explicitly consider examples of the two-dimensional, antiferromagnetic Heisenberg model and the one-dimensional, long-range transverse field Ising model to illustrate the technique.
Towards 4-point correlation functions of any (1/2)-BPS operators from supergravity
Energy Technology Data Exchange (ETDEWEB)
Arutyunov, Gleb [II. Institut für Theoretische Physik, Universität Hamburg,Luruper Chaussee 149, Hamburg, 22761 (Germany); Zentrum für Mathematische Physik, Universität Hamburg,Bundesstrasse 55, Hamburg, 20146 (Germany); Frolov, Sergey [Hamilton Mathematics Institute and School of Mathematics, Trinity College,Dublin 2 (Ireland); Klabbers, Rob; Savin, Sergei [II. Institut für Theoretische Physik, Universität Hamburg,Luruper Chaussee 149, Hamburg, 22761 (Germany); Zentrum für Mathematische Physik, Universität Hamburg,Bundesstrasse 55, Hamburg, 20146 (Germany)
2017-04-03
The quartic effective action for Kaluza-Klein modes that arises upon compactification of type IIB supergravity on the five-sphere S{sup 5} is a starting point for computing the four-point correlation functions of arbitrary weight (1/2)-BPS operators in N=4 super Yang-Mills theory in the supergravity approximation. The apparent structure of this action is rather involved, in particular it contains quartic terms with four derivatives which cannot be removed by field redefinitions. By exhibiting intricate identities between certain integrals involving spherical harmonics of S{sup 5} we show that the net contribution of these four-derivative terms to the effective action vanishes. Our result is in agreement with and provides further support to the recent conjecture on the Mellin space representation of the four-point correlation function of any (1/2)-BPS operators in the supergravity approximation.
Correlated basis functions theory of light nuclei. Pt. 1. General description and ground states
Energy Technology Data Exchange (ETDEWEB)
Bosca, M.C.; Guardiola, R.
1988-01-18
The correlated basis functions theory is applied to the description of light (p-shell) nuclei. The interaction used is the Reid potential, in the V8 (central, spin, tensor and spin-orbit) and V6 (no spin-orbit term) forms. Our work includes state-dependent correlation functions, and their radial components are determined by solving the corresponding Euler-Lagrange equations with a healing condition at distance d and with a null derivative; in addition, we impose the sequential condition or the Pauli condition so as to insure convergence. We present results corresponding to the ground state of all nuclei in the p-shell. Our results present a good qualitative behaviour, but are in clear disagreement with experimental values.
Energy-momentum tensor correlation function in Nf = 2 + 1 full QCD at finite temperature
Directory of Open Access Journals (Sweden)
Taniguchi Yusuke
2018-01-01
Full Text Available We measure correlation functions of the nonperturbatively renormalized energy-momentum tensor in Nf = 2 + 1 full QCD at finite temperature by applying the gradient flow method both to the gauge and quark fields. Our main interest is to study the conservation law of the energy-momentum tensor and to test whether the linear response relation is properly realized for the entropy density. By using the linear response relation we calculate the specific heat from the correlation function. We adopt the nonperturba-tively improved Wilson fermion and Iwasaki gauge action at a fine lattice spacing = 0:07 fm. In this paper the temperature is limited to a single value T ≃ 232 MeV. The u, d quark mass is rather heavy with mπ=mρ ≃ 0:63 while the s quark mass is set to approximately its physical value.
Zhou, Jianhui; Chang, Hao-Ran
2018-02-01
We present a unified derivation of the dynamical correlation functions including density-density, density-current and current-current, of three-dimensional Weyl/Dirac semimetals by use of the Passarino-Veltman reduction scheme at zero temperature. The generalized Kramers-Kronig relations with arbitrary order of subtraction are established to verify these correlation functions. Our results lead to the exact chiral magnetic conductivity and directly recover the previous ones in several limits. We also investigate the magnetic susceptibilities, the orbital magnetization, and briefly discuss the impact of electron interactions on these physical quantities within the random phase approximation. Our work could provide a starting point for the investigation of the nonlocal transport and optical properties due to the higher-order spatial dispersion in three-dimensional Weyl/Dirac semimetals.
Generalized MacMahon Gd(q) as q-deformed CFT2 correlation function
International Nuclear Information System (INIS)
Drissi, Lalla Btissam; Jehjouh, Houda; Saidi, El Hassan
2008-01-01
Using Γ ± (z) vertex operators of the c=1 two-dimensional conformal field theory, we give a 2d-quantum field theoretical derivation of the conjectured d-dimensional MacMahon function G d (q). We interpret this function G d (q) as a (d+1)-point correlation function G d+1 (z 0 ,...,z d ) of some local vertex operators O j (z j ). We determine these operators and show that they are particular composites of q-deformed hierarchical vertex operators Γ ± (p) , with a positive integer p. In agreement with literature's results, we find that G d (q), d≥4, cannot be the generating functional of all d-dimensional generalized Young diagrams
Molodij, Guillaume
2011-08-01
A general expression of the spatial correlation functions of quantities related to the phase fluctuations of a wave that have propagated through the atmospheric turbulence are derived. A generalization of the method to integrand containing the product of an arbitrary number of hypergeometric functions is presented. The formalism is able to give the coefficients of phase-expansion functions orthogonal over an arbitrary circularly symmetric weighting function for an isotropic turbulence spectrum, as well as to describe the effect of the finite outer and inner scales of the turbulence and to describe the spherical propagation or to derive the effects of the analytical operators acting on the phase such as the derivatives of any order. The derivation of the generalized integrals with multiparameters is based on the Mellin transforms integration method.
International Nuclear Information System (INIS)
Yokoyama, Eriko; Nagata, Ken; Uemura, Kazuo
1997-01-01
To elucidate the participation of the brain regions in language function, cerebral blood flow (CBF) which were measured with positron emission tomography (PET) were compared with the language scores based on the standard language test for aphasics in 97 right-handed patients with aphasia due to cerebral infarction. PET studies were performed on 71.4±107.3 days after onset. By the linear regression analysis, the aphasic scores were correlated with the regional CBF from 55 brain regions. CBF from the left frontal, left temporal, and left parietal lobes significantly correlated with language scores of auditory comprehension, speaking, reading, writing, calculation, and repetition. Highly significant correlation was obtained from the left posterior inferior frontal, superior temporal, supramarginal and angular gyri. CBF from the right inferior frontal, right superior temporal, right parahippocampal and right anterior cingulate gyri also correlated with the auditory comprehension, speaking and reading. Accordingly, in addition to the classical language areas which play an essential roles in language function, the extensive areas in the left hemisphere and some part of the right hemisphere may be related to the language processing and recovery from aphasia. (author)
Energy Technology Data Exchange (ETDEWEB)
Yokoyama, Eriko; Nagata, Ken; Uemura, Kazuo [Research Inst. for Brain and Blood Vessels, Akita (Japan)
1997-04-01
To elucidate the participation of the brain regions in language function, cerebral blood flow (CBF) which were measured with positron emission tomography (PET) were compared with the language scores based on the standard language test for aphasics in 97 right-handed patients with aphasia due to cerebral infarction. PET studies were performed on 71.4{+-}107.3 days after onset. By the linear regression analysis, the aphasic scores were correlated with the regional CBF from 55 brain regions. CBF from the left frontal, left temporal, and left parietal lobes significantly correlated with language scores of auditory comprehension, speaking, reading, writing, calculation, and repetition. Highly significant correlation was obtained from the left posterior inferior frontal, superior temporal, supramarginal and angular gyri. CBF from the right inferior frontal, right superior temporal, right parahippocampal and right anterior cingulate gyri also correlated with the auditory comprehension, speaking and reading. Accordingly, in addition to the classical language areas which play an essential roles in language function, the extensive areas in the left hemisphere and some part of the right hemisphere may be related to the language processing and recovery from aphasia. (author)
Ma, Q.; Tipping, R. H.; Lavrentieva, N. N.
2012-01-01
By adopting a concept from signal processing, instead of starting from the correlation functions which are even, one considers the causal correlation functions whose Fourier transforms become complex. Their real and imaginary parts multiplied by 2 are the Fourier transforms of the original correlations and the subsequent Hilbert transforms, respectively. Thus, by taking this step one can complete the two previously needed transforms. However, to obviate performing the Cauchy principal integrations required in the Hilbert transforms is the greatest advantage. Meanwhile, because the causal correlations are well-bounded within the time domain and band limited in the frequency domain, one can replace their Fourier transforms by the discrete Fourier transforms and the latter can be carried out with the FFT algorithm. This replacement is justified by sampling theory because the Fourier transforms can be derived from the discrete Fourier transforms with the Nyquis rate without any distortions. We apply this method in calculating pressure induced shifts of H2O lines and obtain more reliable values. By comparing the calculated shifts with those in HITRAN 2008 and by screening both of them with the pair identity and the smooth variation rules, one can conclude many of shift values in HITRAN are not correct.
Haule, Kristjan
2018-04-01
The Dynamical Mean Field Theory (DMFT) in combination with the band structure methods has been able to address reach physics of correlated materials, such as the fluctuating local moments, spin and orbital fluctuations, atomic multiplet physics and band formation on equal footing. Recently it is getting increasingly recognized that more predictive ab-initio theory of correlated systems needs to also address the feedback effect of the correlated electronic structure on the ionic positions, as the metal-insulator transition is almost always accompanied with considerable structural distortions. We will review recently developed extension of merger between the Density Functional Theory (DFT) and DMFT method, dubbed DFT+ embedded DMFT (DFT+eDMFT), whichsuccessfully addresses this challenge. It is based on the stationary Luttinger-Ward functional to minimize the numerical error, it subtracts the exact double-counting of DFT and DMFT, and implements self-consistent forces on all atoms in the unit cell. In a few examples, we will also show how the method elucidated the important feedback effect of correlations on crystal structure in rare earth nickelates to explain the mechanism of the metal-insulator transition. The method showed that such feedback effect is also essential to understand the dynamic stability of the high-temperature body-centered cubic phase of elemental iron, and in particular it predicted strong enhancement of the electron-phonon coupling over DFT values in FeSe, which was very recently verified by pioneering time-domain experiment.
Multiconfiguration Pair-Density Functional Theory: A New Way To Treat Strongly Correlated Systems.
Gagliardi, Laura; Truhlar, Donald G; Li Manni, Giovanni; Carlson, Rebecca K; Hoyer, Chad E; Bao, Junwei Lucas
2017-01-17
The electronic energy of a system provides the Born-Oppenheimer potential energy for internuclear motion and thus determines molecular structure and spectra, bond energies, conformational energies, reaction barrier heights, and vibrational frequencies. The development of more efficient and more accurate ways to calculate the electronic energy of systems with inherently multiconfigurational electronic structure is essential for many applications, including transition metal and actinide chemistry, systems with partially broken bonds, many transition states, and most electronically excited states. Inherently multiconfigurational systems are called strongly correlated systems or multireference systems, where the latter name refers to the need for using more than one ("multiple") configuration state function to provide a good zero-order reference wave function. This Account describes multiconfiguration pair-density functional theory (MC-PDFT), which was developed as a way to combine the advantages of wave function theory (WFT) and density functional theory (DFT) to provide a better treatment of strongly correlated systems. First we review background material: the widely used Kohn-Sham DFT (which uses only a single Slater determinant as reference wave function), multiconfiguration WFT methods that treat inherently multiconfigurational systems based on an active space, and previous attempts to combine multiconfiguration WFT with DFT. Then we review the formulation of MC-PDFT. It is a generalization of Kohn-Sham DFT in that the electron kinetic energy and classical electrostatic energy are calculated from a reference wave function, while the rest of the energy is obtained from a density functional. However, there are two main differences with respent to Kohn-Sham DFT: (i) The reference wave function is multiconfigurational rather than being a single Slater determinant. (ii) The density functional is a function of the total density and the on-top pair density rather than
Three-point correlation functions of giant magnons with finite size
International Nuclear Information System (INIS)
Ahn, Changrim; Bozhilov, Plamen
2011-01-01
We compute holographic three-point correlation functions or structure constants of a zero-momentum dilaton operator and two (dyonic) giant magnon string states with a finite-size length in the semiclassical approximation. We show that the semiclassical structure constants match exactly with the three-point functions between two su(2) magnon single trace operators with finite size and the Lagrangian in the large 't Hooft coupling constant limit. A special limit J>>√(λ) of our result is compared with the relevant result based on the Luescher corrections.
Energy Technology Data Exchange (ETDEWEB)
Novaes, Marcel [Instituto de Física, Universidade Federal de Uberlândia, Ave. João Naves de Ávila, 2121, Uberlândia, MG 38408-100 (Brazil)
2015-06-15
We consider the statistics of time delay in a chaotic cavity having M open channels, in the absence of time-reversal invariance. In the random matrix theory approach, we compute the average value of polynomial functions of the time delay matrix Q = − iħS{sup †}dS/dE, where S is the scattering matrix. Our results do not assume M to be large. In a companion paper, we develop a semiclassical approximation to S-matrix correlation functions, from which the statistics of Q can also be derived. Together, these papers contribute to establishing the conjectured equivalence between the random matrix and the semiclassical approaches.
Correlation functions between specific volume and stoichiometry for transition metal nitrides
International Nuclear Information System (INIS)
Soto, G.; Aparicio, E.; Avalos-Borja, M.
2005-01-01
A methodology is proposed to correlate the structural aspects of transition metal nitrides (TMN) to the stoichiometric ratio: x = [N]/[M]. The method is based on a numeric figure, υ, given by the difference between the atomic concentrations of nitride and parent metal normalized to the atomic concentration of parent metal. Numerical regression is used to construct interpolating functions for υ(x) using as input the available data for TMN in two well-recognized databases (ICDD and ICSD). In summary we obtain functions of x that describe the deformation caused in the parent metal lattice by the nitrogen assimilation. The results are attractive, since TMN show remarkable trends
Electron-hydrogen atom inelastic scattering through a correlated wave function
International Nuclear Information System (INIS)
Serpa Vieira, A.E. de.
1984-01-01
The inelastic collision between an electron and a hydrogen atom is studied. A correlated function, used previously to the same system in elastic collisions in which there are two parameters fitted in the energy range studied, is utilized. With this functions an equation is developed for the direct and exchange transition matrix elements to the 15-25 and 15-2 p transitions. The obtained results are compared with Willians experimental measurements, as well the results given by the theoretical treatments of Kingston, Fon and Burke. (L.C.) [pt
Qing, Zhao; Gong, Gaolang
2016-10-01
A fundamental issue in neuroscience is to understand the structural substrates of neural activities. Intrinsic brain activity has been increasingly recognized as an important functional activity mode and is tightly linked with various cognitive functions. Structurally, cognitive functions have also shown a relation with brain volume/size. Therefore, an association between intrinsic brain activities and brain volume/size can be hypothesized, and brain volume/size may impact intrinsic brain activity in human brains. The present study aimed to explicitly investigate this brain structure-function relationship using two large independent cohorts of 176 and 236 young adults. Structural-MRI was performed to estimate the brain volume, and resting-state functional-MRI was applied to extract the amplitude of low-frequency fluctuations (ALFF), an imaging measure of intrinsic brain activity. Intriguingly, our results revealed a robust linear correlation between whole-brain size and ALFF. Moreover, specific brain lobes/regions, including the frontal lobe, the left middle frontal gyrus, anterior cingulate gyrus, Rolandic operculum, and insula, also showed a reliable, positive volume-ALFF correlation in the two cohorts. These findings offer direct, empirical evidence of a strong association between brain size/volume and intrinsic brain activity, as well as provide novel insight into the structural substrates of the intrinsic brain activity of the human brain. Copyright © 2016 Elsevier Inc. All rights reserved.
Correlation of spine deformity, lung function, and seat pressure in spina bifida.
Patel, Jayesh; Walker, Janet L; Talwalkar, Vishwas R; Iwinski, Henry J; Milbrandt, Todd A
2011-05-01
Spinal deformity, a common problem in children with myelodysplasia, is associated with alterations in pulmonary function and sitting balance. Sitting imbalance causes areas of high pressure in patients already at high risk for developing pressure ulcers due to insensate skin. We asked: Does spinal deformity affect pulmonary function tests in children with myelodysplasia? Does the magnitude of spinal curvatures and pelvic obliquity affect seating pressures? Does spinal deformity and seated pressures correlate with a history of pressure ulcers? We retrospectively reviewed 32 patients with myelodysplasia and scoliosis (mean age, 14 years). The mean thoracic scoliosis was 64° with a mean pelvic obliquity of 15°. The mean forced vital capacity was 59% of predicted. The mean of the average and peak seated pressures were 24 and 137 mm Hg, respectively. We examined spinal radiographs, pulmonary function tests, and seated pressure maps and evaluated correlations of spinal deformity measures, pulmonary function, and seated pressures. The thoracic scoliosis inversely correlated with lung volume and weakly related with only the forced midexpiratory volume parameter (R(2) = 31%). The curve magnitude was associated with % seated area with pressures of 38 to 70 mm Hg while lesser degrees of pelvic obliquity were associated with % seating area with pressures of less than 38 mm Hg (R(2) = 25% and 24%, respectively). A history of pressure ulcers did not correlate with any spinal deformity or seated pressure measures. All patients displayed a reduced forced vital capacity, but this reduction was not related to increasing scoliosis. The smaller scoliosis curves and lesser degrees of pelvic obliquity were associated with larger areas of low seated pressures.
Energy Technology Data Exchange (ETDEWEB)
Dai, Hui; Zhang, Yu; Hu, Su; Wang, Ximing; Li, Yonggang; Hu, Chunhong [The First Affiliated Hospital of Soochow University, Department of Radiology, Suzhou, Jiangsu (China); Lai, Lillian [LAC+USC Medical Center, Department of Neuroradiology, Los Angeles, CA (United States); Shen, Hailin [Suzhou Kowloon Hospital, Shanghai Jiao Tong University Medical School, Department of Radiology, Suzhou, Jiangsu (China)
2017-11-15
The relationship between parameters of brain functional networks and clinical indexes is unclear so far in patients with diabetic retinopathy (DR). This paper is to investigate this. Twenty-one patients with different grades of DR and 21 age- and sex-matched healthy controls were enrolled from August 2012 to September 2014. The clinical indexes recorded included DR grade, duration of diabetes, HbA1c, diabetic foot screen, fasting plasma glucose, insulin, Homa-β, Homa-IR, insulin sensitive index (ISI), Mini-Mental State Examination (MMSE), and patient sex and age. Subjects were scanned using 3-T MR with blood-oxygen-level-dependent and 3D-FSPGR sequences. MR data was analyzed via preprocessing and functional network construction, and quantified indexes of network (clustering coefficient, characteristic path length, global efficiency, degree distribution, and small worldness) were evaluated. Statistics consisted of ANOVA and correlation. There were significant differences between patients and controls among clustering coefficient, characteristic path length, degree distribution, and small worldness parameters (P < 0.05). MMSE scores negatively correlated with characteristic path length, and Hb1Ac negatively correlated with small worldness. MMSE, duration of diabetes, diabetic foot screen, fasting plasma glucose, insulin, Homa-β, Homa-IR, ISI, DR grade, and patient age, except from Hb1Ac, correlated with degree distribution in certain brain areas. Brain functional networks are altered, specifically in the areas of visual function and cognition, and these alterations may reflect the severity of visual weakness and cognitive decline in DR patients. Moreover, the brain networks may be affected both by long-standing and instant clinical factors. (orig.)
Correlation functions of integrable models: A description of the ABACUS algorithm
Caux, Jean-Sébastien
2009-09-01
Recent developments in the theory of integrable models have provided the means of calculating dynamical correlation functions of some important observables in systems such as Heisenberg spin chains and one-dimensional atomic gases. This article explicitly describes how such calculations are generally implemented in the ABACUS C++ library, emphasizing the universality in treatment of different cases coming as a consequence of unifying features within the Bethe ansatz.
International Nuclear Information System (INIS)
Dai, Hui; Zhang, Yu; Hu, Su; Wang, Ximing; Li, Yonggang; Hu, Chunhong; Lai, Lillian; Shen, Hailin
2017-01-01
The relationship between parameters of brain functional networks and clinical indexes is unclear so far in patients with diabetic retinopathy (DR). This paper is to investigate this. Twenty-one patients with different grades of DR and 21 age- and sex-matched healthy controls were enrolled from August 2012 to September 2014. The clinical indexes recorded included DR grade, duration of diabetes, HbA1c, diabetic foot screen, fasting plasma glucose, insulin, Homa-β, Homa-IR, insulin sensitive index (ISI), Mini-Mental State Examination (MMSE), and patient sex and age. Subjects were scanned using 3-T MR with blood-oxygen-level-dependent and 3D-FSPGR sequences. MR data was analyzed via preprocessing and functional network construction, and quantified indexes of network (clustering coefficient, characteristic path length, global efficiency, degree distribution, and small worldness) were evaluated. Statistics consisted of ANOVA and correlation. There were significant differences between patients and controls among clustering coefficient, characteristic path length, degree distribution, and small worldness parameters (P < 0.05). MMSE scores negatively correlated with characteristic path length, and Hb1Ac negatively correlated with small worldness. MMSE, duration of diabetes, diabetic foot screen, fasting plasma glucose, insulin, Homa-β, Homa-IR, ISI, DR grade, and patient age, except from Hb1Ac, correlated with degree distribution in certain brain areas. Brain functional networks are altered, specifically in the areas of visual function and cognition, and these alterations may reflect the severity of visual weakness and cognitive decline in DR patients. Moreover, the brain networks may be affected both by long-standing and instant clinical factors. (orig.)
Functional connectivity in resting-state fMRI: Is linear correlation sufficient?
Czech Academy of Sciences Publication Activity Database
Hlinka, Jaroslav; Paluš, Milan; Vejmelka, Martin; Mantini, D.; Corbetta, M.
2011-01-01
Roč. 54, č. 3 (2011), s. 2218-2225 ISSN 1053-8119 R&D Projects: GA MŠk 7E08027 EU Projects: European Commission(XE) 200728 - BRAINSYNC Institutional research plan: CEZ:AV0Z10300504 Keywords : fMRI * functional connectivity * Gaussianity * nonlinearity * correlation * mutual information Subject RIV: FH - Neurology Impact factor: 5.895, year: 2011
An integral constraint for the evolution of the galaxy two-point correlation function
International Nuclear Information System (INIS)
Peebles, P.J.E.; Groth, E.J.
1976-01-01
Under some conditions an integral over the galaxy two-point correlation function, xi(x,t), evolves with the expansion of the universe in a simple manner easily computed from linear perturbation theory.This provides a useful constraint on the possible evolution of xi(x,t) itself. We test the integral constraint with both an analytic model and numerical N-body simulations for the evolution of irregularities in an expanding universe. Some applications are discussed. (orig.) [de
2015-10-01
AWARD NUMBER: W81XWH-08-1-0726 TITLE: Family Functioning and Soldier PTSD: Correlates of Treatment Engagement and Military Job Satisfaction ...and Military Job Satisfaction 5b. GRANT NUMBER W81XWH-08-1-0726 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Leyla Stambaugh, Ph.D.; Dawn Ohse, Ph.D. 5d...engagement, and Soldier job satisfaction in active duty Soldiers with PTSD. The specific aim was to identify facilitators of Soldier treatment
Interaction of Variational Localised Correlation Functions for Atomic Properties of Be I
International Nuclear Information System (INIS)
Verdebout, S; Godefroid, M; Rynkun, P; Gaigalast, G; Jönsson, P; Froese Fischer, C
2012-01-01
We present some progress associated to the localised correlation function interaction (LCFI) method. In this report, the LCFI method is tested not only for total energy but also for the specific mass shift operator, the hyperfine structure parameters and the transition probabilities. These properties are computed for the three lowest electronic states of the beryllium atom. These calculations illustrate the importance of the contraction effects.
Azimuthal correlation functions and the energy of vanishing flow in nucleus-nucleus collisions
International Nuclear Information System (INIS)
Angelique, J.C.; Bizard, G.; Brou, R.; Cussol, D.; Kerambrun, A.; Patry, J.P.; Peter, J.; Regimbart, R.; Steckmeyer, J.C.; Tamain, B.; Vient, E.; Cassagnou, Y.; Legrain, R.; Eudes, P.; Lebrun, C.; He, Z.Y.; Crema, E.; Sao Paulo Univ., SP
1994-06-01
A novel method is proposed for studying the evolution of flow phenomena with the incident energy, and for quantitatively estimating the energy of vanishing flow (also called balance energy, E bal ) without reconstructing the reaction plane. We used a method based on the shapes of experimental particle-particle azimuthal correlation functions to determine E bal for three systems: Ar + Al, Zn + Ti, Zn + Ni. We compare the results with estimations using flow parameter analysis and also with theoretical expectations. (authors)
Zaheer, Sana; Beg, Mujahid; Rizvi, Imran; Islam, Najmul; Ullah, Ekram; Akhtar, Nishat
2013-10-01
The use of biomarkers to predict stroke prognosis is gaining particular attention nowadays. Neuron specific enolase (NSE), which is a dimeric isoenzyme of the glycolytic enzyme enolase and is found mainly in the neurons is one such biomarker. This study was carried out on patients of acute ischemic stroke with the aims to determine the correlation between NSE levels on the day of admission with infarct volume, stroke severity, and functional neurological outcome on day 30. Seventy five patients of acute ischemic stroke admitted in the Department of Medicine were included in the study. Levels of NSE were determined on day 1 using the human NSE ELISA kit (Alpha Diagnostic International Texas 78244, USA). Volume of infarct was measured by computed tomography (CT) scan using the preinstalled software Syngo (version A40A) of Siemen's medical solutions (Forchheim, Germany). Stroke severity at admission was assessed using Glasgow coma scale (GCS) and functional neurological outcome was assessed using modified Rankin scale (mRS) on day 30. Statistical analysis was performed using the SPSS software for windows version 15.0 (SPSS). A positive correlation was found between concentration of NSE on day 1 and infarct volume determined by CT scan (r = 0.955, P < 0.001). A strong negative correlation was found between GCS at presentation and concentration of NSE on day 1 (r = -0.806, P < 0.001). There was a positive correlation between NSE levels at day 1 and functional neurological outcome assessed by mRS at day 30 (r = 0.744, P < 0.001). Serum levels of NSE in first few days of ischemic stroke can serve as a useful marker to predict stroke severity and early functional outcome. However, larger studies with serial estimation of NSE are needed to establish these observations more firmly.
Studies on eletron scattering by hydrogen atoms through of a correlationed wave function
International Nuclear Information System (INIS)
Jacchieri, S.G.
1982-01-01
A correlationed wave function dependent of two adjustable parameters ( α e β), aiming describe a system formed by an electron and a hydrogen atom is studied. Some elastic differential cross-sections for several values of α and β parameters, scattering angle of 2 0 to 140 0 and energies of 50 eV and 680 eV are presented. (M.J.C.) [pt
de Matos, Ana Cristina Carvalho; Câmara, Niels Olsen Saraiva; de Oliveira, Ana Francisca Franco; Franco, Marcello F; Moura, Luiz Antonio Ribeiro; Nishida, Sonia; Pereira, Aparecido Bernardo; Pacheco-Silva, Alvaro
2010-05-01
Renal transplant patients with stable graft function and proximal tubular dysfunction (PTD) have an increased risk for chronic allograft nephropathy (CAN). In this study, we investigated the histologic pattern associated with PTD and its correlation with graft outcome. Forty-nine transplant patients with stable graft function were submitted to a biopsy. Simultaneously, urinary retinol-binding protein (uRBP) was measured and creatinine clearance was also determined. Banff's score and semi-quantitative histologic analyses were performed to assess tubulointerstitial alterations. Patients were followed for 24.0 + or - 7.8 months. At biopsy time, mean serum creatinine was 1.43 + or - 0.33 mg/dl. Twelve patients (24.5%) had uRBP > or = 1 mg/l, indicating PTD and 67% of biopsies had some degree of tubulointerstitial injury. At the end of the study period, 18 (36.7%) patients had lost renal function. uRBP levels were not associated with morphologic findings of interstitial fibrosis and tubular atrophy (IF/TA), interstitial fibrosis measured by Sirius red or tubulointerstitial damage. However, in multivariate analysis, the only variable associated with the loss of renal function was uRBP level > or = 1 mg/l, determining a risk of 5.290 of loss of renal function (P = 0.003). Renal transplant patients who present PTD have functional alteration, which is not associated with morphologic alteration. This functional alteration is associated to progressive decrease in renal function.
Correlation between middle-ear pressure-regulation functions and outcome of type-I tympanoplasty.
Takahashi, Haruo; Sato, Hiroaki; Nakamura, Hajime; Naito, Yasushi; Umeki, Hiroshi
2007-06-01
To examine the correlation between the middle-ear pressure-regulation functions including active eustachian tube (ET) functions and transmucosal gas exchange function, and outcome of tympanoplasty. Seventy five patients (78 ears) with non-cholesteatomatous chronic otitis media with eardrum perforation but without ossicular damage or middle-ear anomaly participated in this study. Before surgery, patency of the ET was examined by applying positive pressure to the middle ear through the eardrum perforation, and then the ET pressure-regulation functions were examined using the inflation-deflation test. Also their transmucosal gas exchange function was evaluated by examining the presence or absence of aeration in the mastoid on the CT before surgery or through the microscope during the surgery. All of them underwent type-I tympanoplasty, and their postoperative conditions including the hearing were followed for more than 6 months. The outcome of the surgery was judged as poor outcome when they had any of the following conditions; more than 20 dB of mean air-bone gap, spontaneous perforation within 6 months, or persistent wet condition including recurrent otorrhea. First, the outcome of all the four ears of which ETs were considered mechanically obstructed was poor. Next, among the remaining 74 ears, none of the three individual parameters, including positive and negative middle-ear pressure-equalizing functions and mastoid aeration, showed significantly positive correlation with the outcome of the surgery, but significantly higher incidence of poor outcome was seen only when all the three parameters were poor. These results indicated that impairment of all the middle-ear pressure-regulation functions was likely to cause poor outcome of tympanoplasty, and also allowed us reconfirm that ears with mechanically obstructed ETs were contraindicated for tympanoplasty. Therefore, assessment of mastoid condition is important as well as the ET function before tympanoplasty.
Lee, H C
1998-01-01
First, we have investigated chiral edges of a quantum Hall liquids at filling factor nu=2. The separation of spin and charge degrees of freedom becomes manifest in the presence of long- range Coulomb interaction. Due to the spin-charge separation the tunneling density of states takes the form D(omega) approx ( -lnl omega l) sup 1 sup / sup 2. Experimentally, the spin-charge separation can be revealed in the temperature and voltage dependence of the tunneling current into Fermi liquid reservoir. Second, the charge and spin correlation functions of partially spin-polarized edge electrons of a quantum Hall bar are studied using effective Hamiltonian and bosonization techniques. In the presence of the Coulomb interaction between the edges with opposite chirality we find a different crossover behavior in spin and charge correlation functions. The crossover of the spin correlation function in the Coulomb dominated regime is characterized by an anomalous exponent, which originates from the finite value of the effect...
Schiavella, Mauro; Pelagatti, Matteo; Westin, Jerker; Lepore, Gabriele; Cherubini, Paolo
2018-01-12
Poker playing and responsible gambling both entail the use of the executive functions (EF), which are higher-level cognitive abilities. This study investigated if online poker players of different ability showed different performances in their EF and if so, which functions were the most discriminating for their playing ability. Furthermore, it assessed if the EF performance was correlated to the quality of gambling, according to self-reported questionnaires (PGSI, SOGS, GRCS). Three poker experts evaluated anonymized poker hand history files and, then, a trained professional administered an extensive neuropsychological test battery. Data analysis determined which variables of the tests correlated with poker ability and gambling quality scores. The highest correlations between EF test results and poker ability and between EF test results and gambling quality assessment showed that mostly different clusters of executive functions characterize the profile of the strong(er) poker player and those ones of the problem gamblers (PGSI and SOGS) and the one of the cognitions related to gambling (GRCS). Taking into consideration only the variables overlapping between PGSI and SOGS, we found some key predictive factors for a more risky and harmful online poker playing: a lower performance in the emotional intelligence competences (Emotional Quotient inventory Short) and, in particular, those grouped in the Intrapersonal scale (emotional self-awareness, assertiveness, self-regard, independence and self-actualization).
Mirage in temporal correlation functions for baryon-baryon interactions in lattice QCD
International Nuclear Information System (INIS)
Iritani, T.; Doi, T.; Aoki, S.; Gongyo, S.; Hatsuda, T.; Ikeda, Y.; Inoue, T.; Ishii, N.; Murano, K.; Nemura, H.; Sasaki, K.
2016-01-01
Single state saturation of the temporal correlation function is a key condition to extract physical observables such as energies and matrix elements of hadrons from lattice QCD simulations. A method commonly employed to check the saturation is to seek for a plateau of the observables for large Euclidean time. Identifying the plateau in the cases having nearby states, however, is non-trivial and one may even be misled by a fake plateau. Such a situation takes place typically for a system with two or more baryons. In this study, we demonstrate explicitly the danger from a possible fake plateau in the temporal correlation functions mainly for two baryons (ΞΞ and NN), and three and four baryons ( 3 He and 4 He) as well, employing (2+1)-flavor lattice QCD at m π =0.51 GeV on four lattice volumes with L= 2.9, 3.6, 4.3 and 5.8 fm. Caution is required when drawing conclusions about the bound NN, 3N and 4N systems based only on the standard plateau fitting of the temporal correlation functions.
General solution of an exact correlation function factorization in conformal field theory
International Nuclear Information System (INIS)
Simmons, Jacob J H; Kleban, Peter
2009-01-01
The correlation function factorization with K a boundary operator product expansion coefficient, is known to hold for certain scaling operators at the two-dimensional percolation point and in a few other cases. Here the correlation functions are evaluated in the upper half-plane (or any conformally equivalent region) with x 1 and x 2 arbitrary points on the real axis, and z an arbitrary point in the interior. This type of result is of interest because it is both exact and universal, relates higher-order correlation functions to lower-order ones and has a simple interpretation in terms of cluster or loop probabilities in several statistical models. This motivated us to use the techniques of conformal field theory to determine the general conditions for its validity. Here, we discover that either (see display) factorizes in this way for any central charge c, generalizing previous results. In particular, the factorization holds for either FK (Fortuin–Kasteleyn) or spin clusters in the Q-state Potts models; it also applies to either the dense or dilute phases of the O(n) loop models. Further, only one other non-trivial set of highest-weight operators (in an irreducible Verma module) factorizes in this way. In this case the operators have negative dimension (for c<1) and do not seem to have a physical realization
International Nuclear Information System (INIS)
Akemann, Gernot; Checinski, Tomasz; Kieburg, Mario
2016-01-01
We compute the spectral statistics of the sum H of two independent complex Wishart matrices, each of which is correlated with a different covariance matrix. Random matrix theory enjoys many applications including sums and products of random matrices. Typically ensembles with correlations among the matrix elements are much more difficult to solve. Using a combination of supersymmetry, superbosonisation and bi-orthogonal functions we are able to determine all spectral k -point density correlation functions of H for arbitrary matrix size N . In the half-degenerate case, when one of the covariance matrices is proportional to the identity, the recent results by Kumar for the joint eigenvalue distribution of H serve as our starting point. In this case the ensemble has a bi-orthogonal structure and we explicitly determine its kernel, providing its exact solution for finite N . The kernel follows from computing the expectation value of a single characteristic polynomial. In the general non-degenerate case the generating function for the k -point resolvent is determined from a supersymmetric evaluation of the expectation value of k ratios of characteristic polynomials. Numerical simulations illustrate our findings for the spectral density at finite N and we also give indications how to do the asymptotic large- N analysis. (paper)
Small-angle neutron scattering correlation functions of bulk magnetic materials.
Mettus, Denis; Michels, Andreas
2015-10-01
On the basis of the continuum theory of micromagnetics, the correlation function of the spin-misalignment small-angle neutron scattering cross section of bulk ferromagnets ( e.g. elemental polycrystalline ferromagnets, soft and hard magnetic nanocomposites, nanoporous ferromagnets, or magnetic steels) is computed. For such materials, the spin disorder which is related to spatial variations in the saturation magnetization and magnetic anisotropy field results in strong spin-misalignment scattering dΣ M /dΩ along the forward direction. When the applied magnetic field is perpendicular to the incoming neutron beam, the characteristics of dΣ M /dΩ ( e.g. the angular anisotropy on a two-dimensional detector or the asymptotic power-law exponent) are determined by the ratio of magnetic anisotropy field strength H p to the jump Δ M in the saturation magnetization at internal interfaces. Here, the corresponding one- and two-dimensional real-space correlations are analyzed as a function of applied magnetic field, the ratio H p /Δ M , the single-particle form factor and the particle volume fraction. Finally, the theoretical results for the correlation function are compared with experimental data on nanocrystalline cobalt and nickel.
Directory of Open Access Journals (Sweden)
Kyrylo Bessonov
Full Text Available Analyzing time-course expression data captured in microarray datasets is a complex undertaking as the vast and complex data space is represented by a relatively low number of samples as compared to thousands of available genes. Here, we developed the Interdependent Correlation Clustering (ICC method to analyze relationships that exist among genes conditioned on the expression of a specific target gene in microarray data. Based on Correlation Clustering, the ICC method analyzes a large set of correlation values related to gene expression profiles extracted from given microarray datasets. ICC can be applied to any microarray dataset and any target gene. We applied this method to microarray data generated from wine fermentations and selected NSF1, which encodes a C2H2 zinc finger-type transcription factor, as the target gene. The validity of the method was verified by accurate identifications of the previously known functional roles of NSF1. In addition, we identified and verified potential new functions for this gene; specifically, NSF1 is a negative regulator for the expression of sulfur metabolism genes, the nuclear localization of Nsf1 protein (Nsf1p is controlled in a sulfur-dependent manner, and the transcription of NSF1 is regulated by Met4p, an important transcriptional activator of sulfur metabolism genes. The inter-disciplinary approach adopted here highlighted the accuracy and relevancy of the ICC method in mining for novel gene functions using complex microarray datasets with a limited number of samples.
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Yiming Hu
2017-06-01
Full Text Available Accurate prediction of disease risk based on genetic factors is an important goal in human genetics research and precision medicine. Advanced prediction models will lead to more effective disease prevention and treatment strategies. Despite the identification of thousands of disease-associated genetic variants through genome-wide association studies (GWAS in the past decade, accuracy of genetic risk prediction remains moderate for most diseases, which is largely due to the challenges in both identifying all the functionally relevant variants and accurately estimating their effect sizes. In this work, we introduce PleioPred, a principled framework that leverages pleiotropy and functional annotations in genetic risk prediction for complex diseases. PleioPred uses GWAS summary statistics as its input, and jointly models multiple genetically correlated diseases and a variety of external information including linkage disequilibrium and diverse functional annotations to increase the accuracy of risk prediction. Through comprehensive simulations and real data analyses on Crohn's disease, celiac disease and type-II diabetes, we demonstrate that our approach can substantially increase the accuracy of polygenic risk prediction and risk population stratification, i.e. PleioPred can significantly better separate type-II diabetes patients with early and late onset ages, illustrating its potential clinical application. Furthermore, we show that the increment in prediction accuracy is significantly correlated with the genetic correlation between the predicted and jointly modeled diseases.
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Wataru Kobayashi
2015-01-01
Full Text Available Purpose. To determine the correlation of reduced retinal thickness in the central papillomacular bundle (CPB to central visual function, including central retinal sensitivity and visual acuity, in glaucoma patients. Methods. This study enrolled 50 eyes of 50 patients with open-angle glaucoma who were carefully screened for comorbid conditions that can cause decreased central visual function, such as cataracts or macular diseases. We used a novel CPB analysis comprising a program for optical coherence tomography that measured RNFL thickness and GCC thickness in the CPB and divided lengthwise into three parts (upper, middle, and lower CPB. The relationship of these parameters, including conventional macular thickness, to visual field sensitivity in four central standard automated perimetry points (the central four thresholds and BCVA was analyzed. Results. The two parameters most highly correlated with central four thresholds were macular GCCT and macular RNFLT. The two parameters most highly correlated with BCVA were middle CPB (mid-CPB GCCT and mid-CPB RNFLT. A multiple regression analysis revealed that mid-CPB GCCT was an independent factor impacting central retinal thresholds and BCVA. Conclusions. Our results suggest that mid-CPB RNFLT and GCCT, parameters of a novel papillomacular bundle analysis, are candidate biomarkers of decreased central visual function in glaucomatous eyes.
Gauge-fixing parameter dependence of two-point gauge-variant correlation functions
International Nuclear Information System (INIS)
Zhai, C.
1996-01-01
The gauge-fixing parameter ξ dependence of two-point gauge-variant correlation functions is studied for QED and QCD. We show that, in three Euclidean dimensions, or for four-dimensional thermal gauge theories, the usual procedure of getting a general covariant gauge-fixing term by averaging over a class of covariant gauge-fixing conditions leads to a nontrivial gauge-fixing parameter dependence in gauge-variant two-point correlation functions (e.g., fermion propagators). This nontrivial gauge-fixing parameter dependence modifies the large-distance behavior of the two-point correlation functions by introducing additional exponentially decaying factors. These factors are the origin of the gauge dependence encountered in some perturbative evaluations of the damping rates and the static chromoelectric screening length in a general covariant gauge. To avoid this modification of the long-distance behavior introduced by performing the average over a class of covariant gauge-fixing conditions, one can either choose a vanishing gauge-fixing parameter or apply an unphysical infrared cutoff. copyright 1996 The American Physical Society
Montoya-Castillo, Andrés; Reichman, David R.
2017-02-01
The ability to efficiently and accurately calculate equilibrium time correlation functions of many-body condensed phase quantum systems is one of the outstanding problems in theoretical chemistry. The Nakajima-Zwanzig-Mori formalism coupled to the self-consistent solution of the memory kernel has recently proven to be highly successful for the computation of nonequilibrium dynamical averages. Here, we extend this formalism to treat symmetrized equilibrium time correlation functions for the spin-boson model. Following the first paper in this series [A. Montoya-Castillo and D. R. Reichman, J. Chem. Phys. 144, 184104 (2016)], we use a Dyson-type expansion of the projected propagator to obtain a self-consistent solution for the memory kernel that requires only the calculation of normally evolved auxiliary kernels. We employ the approximate mean-field Ehrenfest method to demonstrate the feasibility of this approach. Via comparison with numerically exact results for the correlation function Cz z(t ) =Re ⟨σz(0 ) σz(t ) ⟩ , we show that the current scheme affords remarkable boosts in accuracy and efficiency over bare Ehrenfest dynamics. We further explore the sensitivity of the resulting dynamics to the choice of kernel closures and the accuracy of the initial canonical density operator.
Frequency domain analysis of electrooculogram and its correlation with cardiac sympathetic function.
Kuo, Terry B J; Yang, Cheryl C H
2009-05-01
To test the hypothesis that electrooculogram contains information on autonomic functions, correlation analyses of electrooculogram and heart rate variability (HRV) parameters during night sleep and over 24 h were performed on 24 healthy young volunteers (12 women and 12 men). Continuous frequency-domain analysis revealed repeated emergence of electrooculogram low-frequency power (PEOG, 0.05-0.5 Hz) during night sleep. The change in the PEOG, when natural log transformed, was graded rather than all or nothing. The PEOG was not correlated with high-frequency power (HF, 0.15-0.4 Hz) of HRV. In contrast, the PEOG was significantly correlated with R-R interval (r=-0.46+/-0.15; mean+/-SD, PHz) to HF ratio (LF/HF) of HRV (r=0.49+/-0.10, P<0.05). The correlation coefficient between PEOG and R-R interval and between PEOG and LF/HF became even larger (r=-0.68+/-0.08 and 0.58+/-0.09, respectively) when 24-h recordings were analyzed. There was no significant difference in the correlation between women and men. We concluded that the electrooculogram, as analyzed in the frequency domain, contains information on sympathetic activity not only during night sleep but also throughout day and night in healthy young people.
Melia, F.; López-Corredoira, M.
2018-03-01
Aim. The lack of large-angle correlations in the fluctuations of the cosmic microwave background (CMB) conflicts with predictions of slow-roll inflation. But while probabilities (≲0.24%) for the missing correlations disfavour the conventional picture at ≳3σ, factors not associated with the model itself may be contributing to the tension. Here we aim to show that the absence of large-angle correlations is best explained with the introduction of a non-zero minimum wave number kmin for the fluctuation power spectrum P(k). Methods: We assumed that quantum fluctuations were generated in the early Universe with a well-defined power spectrum P(k), although with a cut-off kmin ≠ 0. We then re-calculated the angular correlation function of the CMB and compared it with Planck observations. Results: The Planck 2013 data rule out a zero kmin at a confidence level exceeding 8σ. Whereas purely slow-roll inflation would have stretched all fluctuations beyond the horizon, producing a P(k) with kmin = 0 - and therefore strong correlations at all angles - a kmin ≠ 0 would signal the presence of a maximum wavelength at the time (tdec) of decoupling. This argues against the basic inflationary paradigm, and perhaps even suggests non-inflationary alternatives, for the origin and growth of perturbations in the early Universe. In at least one competing cosmology, the Rh = ct universe, the inferred kmin corresponds to the gravitational radius at tdec.
Barthel, H Richard; Peniston, John H; Clark, Michael B; Gold, Morris S; Altman, Roy D
2010-01-01
Nonsteroidal anti-inflammatory drugs are recommended for the relief of pain associated with hand osteoarthritis (OA) but do not alter the underlying structural changes that contribute to impaired physical function. The current analysis examined the relationship of pain relief with measures of function and global rating of disease in patients with hand OA. This was a combined analysis of 2 prospective, randomized, double-blind, 8-week, multicenter, parallel-group studies comparing diclofenac sodium 1% gel with placebo gel (vehicle) in patients with radiographically confirmed mild to moderate hand OA. Patients (n = 783) aged > or = 40 years applied diclofenac sodium 1% gel (2 g) or vehicle to each hand 4 times daily for 8 weeks. Outcome measures included pain intensity assessed on a 100-mm Visual Analog Scale (VAS); the Australian/Canadian Osteoarthritis Hand Index (AUSCAN) subscales for pain, stiffness, and physical function (100-mm VAS); and a global rating of disease (100-mm VAS). Change in VAS pain intensity from baseline to week 8 was categorized ( or = 70%) without regard to treatment and compared in each category with the mean change from baseline in each AUSCAN subindex and the global rating of disease. Pearson correlations between changes in outcome measures from baseline to week 8 were calculated. Changes in VAS pain intensity were accompanied by similar changes in AUSCAN scores and global rating of disease. Pearson correlations confirmed significant associations (P < 0.001) between change in VAS pain intensity and changes in AUSCAN pain (correlation coefficient [r] = 0.81), AUSCAN function (r = 0.75), AUSCAN stiffness (r = 0.66), and global rating of disease (r = 0.76). Pain relief correlated with improvements in physical function, stiffness, and global rating of disease in patients with hand OA, irrespective of treatment. This suggests that pain or anticipation of pain inhibits physical function and influences patient perception of disease severity in
Sexual dysfunction in male stroke patients: correlation between brain lesions and sexual function.
Jung, Jea-Hun; Kam, Sung-Chul; Choi, Sae-Min; Jae, Sung-Uk; Lee, Seung-Hyun; Hyun, Jae-Seog
2008-01-01
To identify the sexual function of, and effect of the location of brain lesions on sexual function in, stroke patients. We conducted a survey on 109 stroke patients (64.93 +/- 8.81 years) and 109 age-matched controls (64.69 +/- 8.85 years). We used a questionnaire that included the five-item version of the International Index of Erectile Function (IIEF-5) and questions about changes in sexual desire, ejaculatory function, and sexual satisfaction after a stroke. We analyzed the correlation between the results of the questionnaire and the locations of brain lesions. Erectile function was significantly decreased in the stroke patient group (IIEF-5, 5.89 +/- 7.08) compared with the control group (IIEF-5, 10.67 +/- 7.10). In most patients, the frequency of intercourse and sexual desire decreased after stroke, and an ejaculation disorder accompanied intercourse, but fear regarding intercourse was not severe. A lack of sexual desire was the largest cause (59.4%) of an absence of sexual intercourse. In cases with lesions in the right cerebellum and the left basal ganglia, a significant ejaculation disorder and decrease of sexual desire were more likely to occur, respectively. The sexual desire, erectile function, and ejaculatory function were impaired after stroke. A lack of sexual desire was the major cause of an absence of sexual intercourse. The specific locations of the stroke lesions, such as the left basal ganglia and right cerebellum, might be associated with sexual desire and ejaculation disorder, respectively.
Skresanova, Iryna V; Barannik, Evgen A
2012-07-01
Ultrasound Doppler methods are widely used in clinical practice as prospective investigational tool to study the vascular system and soft biological tissues. Meanwhile, the most general relationship between the power Doppler spectra, spectral characteristics of the scattering fluctuations and the probing ultrasound field parameters for some clinical implementations are still unexplored. Based upon the continuum model of scattering inhomogeneities, a set of the closed-form expressions for the correlation functions and the spectra of Doppler response of soft tissues and blood have been derived. The influence of the correlation among inhomogeneities and the diffusion processes on the Doppler power spectra formed by stationary flows have been examined. Computer simulations of Doppler spectra were performed for different values of correlation radius and diffusion coefficient. With simulation results the effects of the correlation among inhomogeneities and the diffusion processes on the spectral width and mean frequency are established and discussed in respect to turbulent flows. Closed-form expressions for correlation functions and Doppler spectra for the vibrational sonoelastography technique for visualizing malignant tumors in tissues have been derived. Based on the peculiarities of the obtained Doppler spectra, it is shown that the differentiation of soft tissues with respect to the amplitude value of constrained oscillations is feasible. The expressions were derived for the cases of non-stationary accelerated blood movement. It has been found that the frequency dependence reveals solely at a finite time of observation and depends on the initial phase of the accelerated movement. Copyright Â© 2012 Elsevier B.V. All rights reserved.
Correlation of lumbar-hip kinematics between trunk flexion and other functional tasks.
Alqhtani, Raee S; Jones, Michael D; Theobald, Peter S; Williams, Jonathan M
2015-01-01
The purpose of this study was to explore the relationship between the kinematic profiles of flexion of the upper lumbar and lower lumbar (LL) spine and hip and 3 sagittally dominant functional tasks (lifting, stand-to-sit, and sit-to-stand). Fifty-three participants were recruited for this study. Four sensors were attached to the skin over the S1, L3, T12, and lateral thigh. Relative angles between adjacent sensors were used to quantify the motion for the hip, LL, and upper lumbar spine. Pearson correlation coefficients were used to explore the relationship between the movements and more functional tasks. One-way analysis of variance was used to determine the significance of differences between the variables. Flexion resulted in a greater or similar range of motion (ROM) to the other tasks investigated for both spinal regions but less ROM for the hip. Strong correlations for ROM are reported between forward flexion tasks and lifting for the LL spine (r = 0.83) and all regions during stand-to-sit and sit-to-stand (r = 0.70-0.73). No tasks were strongly correlated for velocity (r = 0.03-0.55). Strong correlations were only evident for the LL spine ROM between lifting and flexion; all other tasks afforded moderate or weak correlations. This study suggests that sagittal tasks use different lumbar-hip kinematics and place different demands on the lumbar spine and hip. Copyright © 2015 National University of Health Sciences. Published by Elsevier Inc. All rights reserved.
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Antonio Carlos Tenor Junior
2016-06-01
Full Text Available ABSTRACT OBJECTIVE: To correlate the functional outcomes and radiographic indices of proximal humerus fractures treated using an anatomical locking plate for the proximal humerus. METHODS: Thirty-nine patients with fractures of the proximal humerus who had been treated using an anatomical locking plate were assessed after a mean follow-up of 27 months. These patients were assessed using the University of California Los Angeles (UCLA score and their range of motion was evaluated using the method of the American Academy of Orthopedic Surgeons on the operated shoulder and comparative radiographs on both shoulders. The correlation between radiographic measurements and functional outcomes was established. RESULTS: We found that 64% of the results were good or excellent, according to the UCLA score, with the following means: elevation of 124°; lateral rotation of 44°; and medial rotation of thumb to T9. The type of fracture according to Neer's classification and the patient's age had significant correlations with the range of motion, such that the greater the number of parts in the fracture and the greater the patient's age were, the worse the results also were. Elevation and UCLA score were found to present associations with the anatomical neck-shaft angle in anteroposterior view; fractures fixed with varus deviations greater than 15° showed the worst results (p < 0.001. CONCLUSION: The variation in the neck-shaft angle measurements in anteroposterior view showed a significant correlation with the range of motion; varus deviations greater than 15° were not well tolerated. This parameter may be one of the predictors of functional results from proximal humerus fractures treated using a locking plate.
Operator theory of angular momentum nad orientational auto-correlation functions
International Nuclear Information System (INIS)
Evans, M.W.
1982-01-01
The rigorous relation between the orientational auto-correlation function and the angular momentum autocorrelation function is described in two cases of interest. First when description of the complete zero THz- spectrum is required from the Mori continued fraction expansion for the angular momentum autocorrelation function and second when rotation/translation effects are important. The Mori-Evans theory of 1976, relying on the simple Shimizu relation is found to be essentially unaffected by the higher order corrections recently worked out by Ford and co-workers in the Markov limit. The mutual interaction of rotation and translation is important in determining the details of both the orientational and angular momentum auto-correlation function's (a.c.f.'s) in the presence of sample anisotropy or a symmetry breaking field. In this case it is essential to regard the angular momentum a.c.f. as non-Markovian and methods are developed to relate this to the orientational a.c.f. in the presence of rotation/translation coupling. (author)
Correlation functions with fusion-channel multiplicity in W{sub 3} Toda field theory
Energy Technology Data Exchange (ETDEWEB)
Belavin, Vladimir [I.E. Tamm Department of Theoretical Physics, P.N. Lebedev Physical Institute,Leninsky Avenue 53, 119991 Moscow (Russian Federation); Department of Quantum Physics, Institute for Information Transmission Problems,Bolshoy Karetny per. 19, 127994 Moscow (Russian Federation); Estienne, Benoit [LPTHE, CNRS and Université Pierre et Marie Curie,Sorbonne Universités, 4 Place Jussieu, 75252 Paris Cedex 05 (France); Foda, Omar [School of Mathematics and Statistics, University of Melbourne,Parkville, Victoria 3010 (Australia); Santachiara, Raoul [LPTMS, CNRS (UMR 8626), Université Paris-Saclay,15 rue Georges Clémenceau, 91405 Orsay (France)
2016-06-22
Current studies of W{sub N} Toda field theory focus on correlation functions such that the W{sub N} highest-weight representations in the fusion channels are multiplicity-free. In this work, we study W{sub 3} Toda 4-point functions with multiplicity in the fusion channel. The conformal blocks of these 4-point functions involve matrix elements of a fully-degenerate primary field with a highest-weight in the adjoint representation of sl{sub 3}, and a fully-degenerate primary field with a highest-weight in the fundamental representation of sl{sub 3}. We show that, when the fusion rules do not involve multiplicities, the matrix elements of the fully-degenerate adjoint field, between two arbitrary descendant states, can be computed explicitly, on equal footing with the matrix elements of the semi-degenerate fundamental field. Using null-state conditions, we obtain a fourth-order Fuchsian differential equation for the conformal blocks. Using Okubo theory, we show that, due to the presence of multiplicities, this differential equation belongs to a class of Fuchsian equations that is different from those that have appeared so far in W{sub N} theories. We solve this equation, compute its monodromy group, and construct the monodromy-invariant correlation functions. This computation shows in detail how the ambiguities that are caused by the presence of multiplicities are fixed by requiring monodromy-invariance.
Correlation functions with fusion-channel multiplicity in W3 Toda field theory
International Nuclear Information System (INIS)
Belavin, Vladimir; Estienne, Benoit; Foda, Omar; Santachiara, Raoul
2016-01-01
Current studies of W N Toda field theory focus on correlation functions such that the W N highest-weight representations in the fusion channels are multiplicity-free. In this work, we study W 3 Toda 4-point functions with multiplicity in the fusion channel. The conformal blocks of these 4-point functions involve matrix elements of a fully-degenerate primary field with a highest-weight in the adjoint representation of sl 3 , and a fully-degenerate primary field with a highest-weight in the fundamental representation of sl 3 . We show that, when the fusion rules do not involve multiplicities, the matrix elements of the fully-degenerate adjoint field, between two arbitrary descendant states, can be computed explicitly, on equal footing with the matrix elements of the semi-degenerate fundamental field. Using null-state conditions, we obtain a fourth-order Fuchsian differential equation for the conformal blocks. Using Okubo theory, we show that, due to the presence of multiplicities, this differential equation belongs to a class of Fuchsian equations that is different from those that have appeared so far in W N theories. We solve this equation, compute its monodromy group, and construct the monodromy-invariant correlation functions. This computation shows in detail how the ambiguities that are caused by the presence of multiplicities are fixed by requiring monodromy-invariance.
DEFF Research Database (Denmark)
Cornaton, Y.; Stoyanova, A.; Jensen, Hans Jørgen Aagaard
2013-01-01
An alternative separation of short-range exchange and correlation energies is used in the framework of second-order range-separated density-functional perturbation theory. This alternative separation was initially proposed by Toulouse and relies on a long-range-interacting wave function instead...... of the noninteracting Kohn-Sham one. When second-order corrections to the density are neglected, the energy expression reduces to a range-separated double-hybrid (RSDH) type of functional, RSDHf, where "f" stands for "full-range integrals" as the regular full-range interaction appears explicitly in the energy...... on the potential energy curves in the equilibrium region, improving the accuracy of binding energies and equilibrium bond distances when second-order perturbation theory is appropriate....
TiO{sub 2} nanoparticle-induced ROS correlates with modulated immune cell function
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Maurer-Jones, Melissa A.; Christenson, Jenna R.; Haynes, Christy L., E-mail: chaynes@umn.edu [University of Minnesota, Department of Chemistry (United States)
2012-12-15
Design of non-toxic nanoparticles will be greatly facilitated by understanding the nanoparticle-cell interaction mechanism on a cell function level. Mast cells are important cells for the immune system's first line of defense, and we can utilize their exocytotic behavior as a model cellular function as it is a conserved process across cell types and species. Perturbations in exocytosis can also have implications for whole organism health. One proposed mode of toxicity is nanoparticle-induced reactive oxygen species (ROS), particularly for titanium dioxide (TiO{sub 2}) nanoparticles. Herein, we have correlated changes in ROS with the perturbation of the critical cell function of exocytosis, using UV light to induce greater levels of ROS in TiO{sub 2} exposed cells. The primary culture mouse peritoneal mast cells (MPMCs) were exposed to varying concentrations of TiO{sub 2} nanoparticles for 24 h. ROS content was determined using 2,7-dihydrodichlorofluorescein diacetate (DCFDA). Cellular viability was determined with the MTT and Trypan blue assays, and exocytosis was measured by the analytical electrochemistry technique of carbon-fiber microelectrode amperometry. MPMCs exposed to TiO{sub 2} nanoparticles experienced a dose-dependent increase in total ROS content. While there was minimal impact of ROS on cellular viability, there is a correlation between ROS amount and exocytosis perturbation. As nanoparticle-induced ROS increases, there is a significant decrease (45 %) in the number of serotonin molecules being released during exocytosis, increase (26 %) in the amount of time for each exocytotic granule to release, and decrease (28 %) in the efficiency of granule trafficking and docking. This is the first evidence that nanoparticle-induced ROS correlates with chemical messenger molecule secretion, possibly making a critical connection between functional impairment and mechanisms contributing to that impairment.
Air trapping on HRCT in asthmatics: correlation with pulmonary function test
International Nuclear Information System (INIS)
Hwang, Jung Hwa; Cha, Chull Hee; Park, Jai Soung; Kim, Young Beom; Lee, Hae Kyung; Choi, Deuk Lin; Kim, Kyung Ho; Park, Choon Sik
1997-01-01
To evaluate on the basis of the pulmonary function test the correlation between the extent of air trapping on HRCT with the severity of airway obstruction and also to identify the prognostic effect of the extent of air trapping after treatment of asthma. Thirty five patients with clinically diagnosed bronchial asthma and air trapping, as seen on HRCT, were included in this study. We quantitatively analysed on HRCT the extent of air trapping and then statistically compared this with the clinical parameters of the pulmonary function test. We classified the patients into two groups on the basis of the pulmonary function test and clinical status : Group 1 (N=35), the total number of asthmatic patients; Group 2 (N=18), relatively stable asthmatics without acute asthmatic attack who showed FEV1 of more than 80% of the predicted value. Using the functional paramenters of PEFR, one of the obijective indicators of improvement in airway obstruction, we also classified the patients into three groups on the basis of interval between treatment and clinical improvement. The result of this was as follows : group 1, asymptomatic group (initial PEFR within normal limit, N=7); group 2, early responder (improvement of PEFR within three hospital days, N=18); group 3, late responder (improvement of PEFR within fourteen hospital days should there be a number here). Using HRCT, we then statistically analysed the differences between the three groups in the extent of air trapping. Among the total of 35 asthmatics, the extent of air trapping on HRCT showed significant correlation with FEV1 (r= -0.6161, p < 0.001) and MEFR (r= -0.6012, p < 0.001). Among the relatively stable asthmatics who showed FEV1 more than 80% of the predicted value, MEFR (r= -0.7553, p < 0.001) and FEF75 (r= -0.7529, p=0.012) showed statistically significant correlation with the extent of air trapping on HRCT, but there was no significant correlation between air trapping on HRCT and FEV1. In the three groups of
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Lopes, Agnaldo Jose [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Pedro Ernesto Univ. Hospital. Dept. of Respiratory Function]. E-mail: phel.lop@uol.com.br; Mogami, Roberto; Capone, Domenico; Jansen, Jose Manoel [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). School of Medical Sciences; Tessarollo, Bernardo [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Dept. of Radiology and Diagnostic Image; Melo, Pedro Lopes de [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. of Biology
2008-05-15
Objective: To correlate tomographic findings with pulmonary function findings, as well as to compare chest X-ray findings with high-resolution computed tomography (HRCT) findings, in patients with silicosis. Methods: A cross-sectional study was conducted in 44 non-smoking patients without a history of tuberculosis. Chest X-ray findings were classified according to the International Labour Organization recommendations. Using a semiquantitative system, the following HRCT findings were measured: the full extent of pulmonary involvement; parenchymal opacities; and emphysema. Spirometry and forced oscillation were performed. Pulmonary volumes were evaluated using the helium dilution method, and diffusing capacity of the lung for carbon monoxide was assessed. Results: Of the 44 patients studied, 41 were male. The mean age was 48.4 years. There were 4 patients who were classified as category 0 based on X-ray findings and as category 1 based on HRCT findings. Using HRCT scans, we identified progressive massive fibrosis in 33 patients, compared with only 23 patients when X-rays were used. Opacity score was found to correlate most closely with airflow, DLCO and compliance. Emphysema score correlated inversely with volume, DLCO and airflow. In this sample of patients presenting a predominance of large opacities (75% of the individuals), the deterioration of pulmonary function was associated with the extent of structural changes. Conclusions: In the early detection of silicosis and the identification of progressive massive fibrosis, HRCT scans are superior to X-rays. (author)
International Nuclear Information System (INIS)
Lopes, Agnaldo Jose; Mogami, Roberto; Capone, Domenico; Jansen, Jose Manoel; Tessarollo, Bernardo; Melo, Pedro Lopes de
2008-01-01
Objective: To correlate tomographic findings with pulmonary function findings, as well as to compare chest X-ray findings with high-resolution computed tomography (HRCT) findings, in patients with silicosis. Methods: A cross-sectional study was conducted in 44 non-smoking patients without a history of tuberculosis. Chest X-ray findings were classified according to the International Labour Organization recommendations. Using a semiquantitative system, the following HRCT findings were measured: the full extent of pulmonary involvement; parenchymal opacities; and emphysema. Spirometry and forced oscillation were performed. Pulmonary volumes were evaluated using the helium dilution method, and diffusing capacity of the lung for carbon monoxide was assessed. Results: Of the 44 patients studied, 41 were male. The mean age was 48.4 years. There were 4 patients who were classified as category 0 based on X-ray findings and as category 1 based on HRCT findings. Using HRCT scans, we identified progressive massive fibrosis in 33 patients, compared with only 23 patients when X-rays were used. Opacity score was found to correlate most closely with airflow, DLCO and compliance. Emphysema score correlated inversely with volume, DLCO and airflow. In this sample of patients presenting a predominance of large opacities (75% of the individuals), the deterioration of pulmonary function was associated with the extent of structural changes. Conclusions: In the early detection of silicosis and the identification of progressive massive fibrosis, HRCT scans are superior to X-rays. (author)
International Nuclear Information System (INIS)
Schuetz, G.; Sandow, S.
1993-05-01
We consider systems of particles hopping stochastically on d-dimensional lattices with space-dependent probabilities. We map the master equation in a Fock space where the dynamics are given by a quantum Hamiltonian (continuous time) or a transfer matrix resp. (discrete time). We show that under certain conditions the time-dependent two-point density correlation function in N-particle steady state can be computed from the probability distribution of a single particle moving in the same environment. Focussing on exclusion models where the lattice site can be occupied by at most one particle we discuss as an example for such a stochastic process a generalized Heisenberg antiferromagnet where the strength of the spin-spin coupling in space-dependent. In discrete time one obtains for one dimensional systems the diagonal-to-diagonal transfer matrix of the two dimensional six vertex model with space dependent vertex weights. For a random distribution of the vertex weights one obtains a version of the random barrier model describing diffusion of particles in disordered media. We derive exact expressions for the average two-point density correlation function in the presence of weak, correlated disorder. (authors)
Reduced density matrix embedding. General formalism and inter-domain correlation functional.
Pernal, Katarzyna
2016-08-03
An embedding method for a one-electron reduced density matrix (1-RDM) is proposed. It is based on partitioning of 1-RDM into domains and describing each domain in the effective potential of the other ones. To assure N-representability of the total 1-RDM N-representability and strong-orthogonality conditions are imposed on the domains. The total energy is given as a sum of single-domain energies and domain-domain electron interaction contributions. Higher than two-body inter-domain interaction terms are neglected. The two-body correlation terms are approximated by deriving inter-domain correlation from couplings of density fluctuations of two domains at a time. Unlike in most density embedding methods kinetic energy is treated exactly and it is not required that densities pertaining to the domains are only weakly overlapping. We propose to treat each domain by a corrected perfect-pairing functional. On a few examples it is shown that the embedding reduced density matrix functional method (ERDMF) yields excellent results for molecules that are well described by a single Lewis structure even if strong static intra-domain or dynamic inter-domain correlation effects must be accounted for.
International Nuclear Information System (INIS)
Ni Hongyan; Qi Ji; Wang Mingshi
2008-01-01
Objective: To investigate the effects of early stage Alzheimer's disease (AD) on white matter (WM) integrity using diffusion tensor imaging (DTI) and its relationship with cognitive function decline. Methods: DTI was performed in 32 subjects, including 14 early AD patients and 18 elder controls (ON) with a 1.5 T MR scanner. Fractional anisotropy (FA) and mean diffusivity (b) values were computed and compared for 9 regions of interest (ROI). Eight standard neuropsychological tests were performed and compared between AD and ON to evaluate basic cognitive capacities of AD. Correlation analysis was applied between FA, D values and scores of neuropsychological tests for all subjects. Results: FA significantly decreased in splenium of the corpus callosum and the posterior parietal-temporal region (S2), and (D)-bar significantly increased in the splenium in AD patients (P<0.05). AD patients showed lower scores compared with ON in all neuropsychological tests (P<0.05). FA of the splenium and S2 positively correlated with several tests scores, while D of multiple ROIs negatively correlated with several tests scores (P<0.05). Conclusions: In the early stage of AD, neuropathology has effect not only on cognitive function, but also on white matter structure, and they have strong relationship. AD patients show white matter changes in specific regions, which reflect loss in cortico-cortical connections. (authors)
Correlates of physical function among stroke survivors: an examination of the 2015 BRFSS.
Ilunga Tshiswaka, D; Seals, S R; Raghavan, P
2018-02-01
To identify the characteristics of stroke survivors with poor physical function. Cross-sectional. Secondary data analyses were performed with the 2015 Behavioral Risk Factor Surveillance System data set. Unadjusted and adjusted logistic regressions were employed to determine the correlates of poor physical function in stroke survivors. Self-reported difficulty with walking and stairs was used as a proxy for physical function. Characteristics such as age, race, sex, difficulty doing errands alone, difficult dressing or bathing alone, health care coverage, time since last routine checkup, and reported financial difficulty with regard to health care access were examined as contributing factors to physical function. Approximately half of all stroke survivors reported having difficulty with walking and stairs (50.3%). As expected, the odds of reporting difficulty with walking and stairs were higher among stroke survivors aged 40 years and above (p physical function was preserved (p physical function. Specifically, blacks/ African Americans had a 5.6% increase in the odds of reporting difficulty with walking and stairs than whites. Moreover, Hispanics reported significantly fewer problems than whites. Overall, similar sociocultural patterns in non-stroke and stroke populations were observed in this study. Copyright © 2017 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.
Functional and nutritional status correlation in elderly patients with hip fracture
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Gonzalo Ramón González González
2012-06-01
Full Text Available Introduction: Hip fractures in elderly patients are related to several factors, among which nutrition and functionality stand out. The presence of alterations in the nutritional state has been related directly with the functional state. Objective: To determine the previous functional state of the patient with a hip fracture, the nutritional state at the moment of admittance and the correlation between both parameters as risk factors for the fracture. Materials and methods: 78 elderly patients with a hip fractured were studied from February 1st, 2009 to December 31st of 2009. The functional and nutritional stated were analyzed. Descriptive statistics and inferential analysis were used with contingency tables to test association with c2. Results: 46.1% were functionally independent and 53.9% had functional impairment. 14.1% presented malnourishment, 48.7% were at risk of malnutrition and 37.2% had normal nutrition. Only the 36.7% with the “nutritional problem” (MNA24 who were independent.
Hanakawa, Takashi; Honda, Manabu; Okada, Tomohisa; Fukuyama, Hidenao; Shibasaki, Hiroshi
2003-06-01
Experts of abacus operation demonstrate extraordinary ability in mental calculation. There is psychological evidence that abacus experts utilize a mental image of an abacus to remember and manipulate large numbers in solving problems; however, the neural correlates underlying this expertise are unknown. Using functional magnetic resonance imaging, we compared the neural correlates associated with three mental-operation tasks (numeral, spatial, verbal) among six experts in abacus operations and eight nonexperts. In general, there was more involvement of neural correlates for visuospatial processing (e.g., right premotor and parietal areas) for abacus experts during the numeral mental-operation task. Activity of these areas and the fusiform cortex was correlated with the size of numerals used in the numeral mental-operation task. Particularly, the posterior superior parietal cortex revealed significantly enhanced activity for experts compared with controls during the numeral mental-operation task. Comparison with the other mental-operation tasks indicated that activity in the posterior superior parietal cortex was relatively specific to computation in 2-dimensional space. In conclusion, mental calculation of abacus experts is likely associated with enhanced involvement of the neural resources for visuospatial information processing in 2-dimensional space.
Correlation of structure and function of the macula in patients with retinitis pigmentosa.
Battu, R; Khanna, A; Hegde, B; Berendschot, T T J M; Grover, S; Schouten, J S A G
2015-07-01
To correlate the structure of the macula, as measured by spectral-domain optical coherence tomography (SD-OCT) and function, as measured by microperimetry (MAIA) in patients with retinitis pigmentosa (RP) and relatively good visual acuity. Prospective, cross-sectional, non-intervention study. Patients with RP. Thirty patients with RP and good central visual acuity were identified. Each patient underwent SD-OCT of the macula and microperimetry. The images were overlaid using the custom-designed software. The retinal sensitivity by microperimetry was correlated with corresponding retinal thickness, as measured by the SD-OCT. ELM, COST, and IS/OS junction were scored as intact, disrupted, or absent. Comparing the retinal sensitivity on the MAIA with various measurements on the SD-OCT. The retinal sensitivity on the MAIA showed a significant correlation with total retinal thickness and outer retinal thickness on the SD-OCT. There was no association with either the inner retinal thickness or the choroidal thickness. ORT showed a statistically significant correlation with the anatomical classification of ELM (r=-0.76, Pmacula in patients with RP. These studies are important to establish surrogate markers that can be used as end points for various tests in future therapeutic clinical trials.
The fluctuation-dissipation relation: how does one compare correlation functions and responses?
International Nuclear Information System (INIS)
Villamaina, D; Baldassarri, A; Puglisi, A; Vulpiani, A
2009-01-01
We discuss the well known Einstein and the Kubo fluctuation-dissipation relations (FDRs) in the wider framework of a generalized FDR for systems with a stationary probability distribution. A multivariate linear Langevin model, which includes dynamics with memory, is used as a treatable example to show how the usual relations are recovered only in particular cases. This study brings to the fore the ambiguities of a check of the FDR done without knowing the significant degrees of freedom and their coupling. An analogous scenario emerges in the dynamics of diluted shaken granular media. There, the correlation between position and velocity of particles, due to spatial inhomogeneities, induces violation of usual FDRs. The search for the appropriate correlation function which could restore the FDR can be more insightful than a definition of 'non-equilibrium' or 'effective temperatures'
Directory of Open Access Journals (Sweden)
Meyer Karin
2001-11-01
Full Text Available Abstract A random regression model for the analysis of "repeated" records in animal breeding is described which combines a random regression approach for additive genetic and other random effects with the assumption of a parametric correlation structure for within animal covariances. Both stationary and non-stationary correlation models involving a small number of parameters are considered. Heterogeneity in within animal variances is modelled through polynomial variance functions. Estimation of parameters describing the dispersion structure of such model by restricted maximum likelihood via an "average information" algorithm is outlined. An application to mature weight records of beef cow is given, and results are contrasted to those from analyses fitting sets of random regression coefficients for permanent environmental effects.
International Nuclear Information System (INIS)
Basovets, S.K.; Krupyanskij, Yu.F.; Kurinov, I.V.; Suzdalev, I.P.; Goldanskij, V.I.; Uporov, I.V.; Shaitan, K.V.; Rubin, A.B.
1988-01-01
A method of Moessbauer Fourier spectroscopy is developed to determine the correlation function of coordinates of a macromolecular system. The method does not require the use of an a priori dynamic model. The application of the method to the analysis of RSMR data for human serum albumin has demonstrated considerable changes in the dynamic behavior of the protein globule when the temperature is changed from 270 to 310 K. The main conclusions of the present work is the simultaneous observation of low-frequency (τ≥10 -9 sec) and high-frequency (τ -9 sec) large-scaled motions, that is the two-humped distribution of correlation times of protein motions. (orig.)
Sexual Function Is Correlated With Body Image and Partnership Quality in Female University Students.
Wallwiener, Stephanie; Strohmaier, Jana; Wallwiener, Lisa-Maria; Schönfisch, Birgitt; Zipfel, Stephan; Brucker, Sara Y; Rietschel, Marcella; Wallwiener, Christian W
2016-10-01
According to the World Health Organization definition, sexual health is more than mere physical sexual function; it also encompasses emotional, mental, and social well-being in relation to sexuality and is not merely the absence of dysfunction or disease. In line with this definition, various studies have reported that female sexual function is associated with partnership quality, body image, and body self-acceptance. To investigate whether female sexual function is influenced by (i) body self-acceptance and (ii) partnership quality, as important factors in psychosocial well-being, and (iii) whether the effects of body self-acceptance are moderated by partnership quality. In total, 2,685 female medical students no older than 35 years from Germany, Austria, and Switzerland completed an anonymous online questionnaire comprising the Female Sexual Function Index (FSFI) and the Self-Acceptance of the Body Scale. Respondents were asked to state whether they had been in a steady partnership in the preceding 6 months. When present, the quality of the partnership status was rated (enamoredness, love, friendship, or conflicted). To determine correlations, group differences, and moderating effects among body self-acceptance, partnership quality, and sexual function, the data were analyzed using Spearman correlations, Kruskal-Wallis tests, and analyses of variance. Female sexual function (FSFI total score). (i) In sexually active women, higher FSFI scores were significantly associated with greater body self-acceptance and a steady partnership during the preceding 6 months. (ii) Total FSFI scores were highest in women who described their partnership as enamored (29.45) or loving (28.55). Lower scores were observed in single women (26.71) and in women who described their partnerships as friendship (25.76) or as emotionally conflicted (23.41). (iii) Total FSFI score was affected by an interaction between body self-acceptance and partnership quality. Body self- acceptance was
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Werner Mark
2008-08-01
Full Text Available Abstract Background Variations in the influenza Hemagglutinin protein contributes to antigenic drift resulting in decreased efficiency of seasonal influenza vaccines and escape from host immune response. We performed an in silico study to determine characteristics of novel variable and conserved motifs in the Hemagglutinin protein from previously reported H3N2 strains isolated from Hong Kong from 1968–1999 to predict viral motifs involved in significant biological functions. Results 14 MEME blocks were generated and comparative analysis of the MEME blocks identified blocks 1, 2, 3 and 7 to correlate with several biological functions. Analysis of the different Hemagglutinin sequences elucidated that the single block 7 has the highest frequency of amino acid substitution and the highest number of co-mutating pairs. MEME 2 showed intermediate variability and MEME 1 was the most conserved. Interestingly, MEME blocks 2 and 7 had the highest incidence of potential post-translational modifications sites including phosphorylation sites, ASN glycosylation motifs and N-myristylation sites. Similarly, these 2 blocks overlap with previously identified antigenic sites and receptor binding sites. Conclusion Our study identifies motifs in the Hemagglutinin protein with different amino acid substitution frequencies over a 31 years period, and derives relevant functional characteristics by correlation of these motifs with potential post-translational modifications sites, antigenic and receptor binding sites.
Gupta, Samriti; Garg, Kapil; Singh, Jagdish
2015-12-01
To evaluate the functional independence of children with hemophilia A and its correlation to radiological joint score. The present cross sectional study was conducted at SPMCHI, SMS Medical College, Jaipur, India. Children in the age group of 4-18 y affected with severe, moderate and mild hemophilia A and with a history of hemarthrosis who attended the OPD, emergency or got admitted in wards of SPMCHI, SMS Medical College were examined. Musculoskeletal function was measured in 98 patients using Functional Independence Score in Hemophilia (FISH) and index joints (joints most commonly affected with repeated bleeding) were assessed radiologically with plain X rays using Pettersson score. The mean FISH score was 28.07 ± 3.90 (range 17-32) with squatting, running and step climbing as most affected tasks. The mean Pettersson score was 3.8 ± 3.2. A significant correlation was found between mean Pettersson score and FISH (r = -0.875, P hemophilia A.
Functional correlates of cognitive dysfunction in multiple sclerosis: A multicenter fMRI Study.
Rocca, Maria A; Valsasina, Paola; Hulst, Hanneke E; Abdel-Aziz, Khaled; Enzinger, Christian; Gallo, Antonio; Pareto, Debora; Riccitelli, Gianna; Muhlert, Nils; Ciccarelli, Olga; Barkhof, Frederik; Fazekas, Franz; Tedeschi, Gioacchino; Arévalo, Maria J; Filippi, Massimo
2014-12-01
In this multicenter study, we applied functional magnetic resonance imaging (fMRI) to define the functional correlates of cognitive dysfunction in patients with multiple sclerosis (MS). fMRI scans during the performance of the N-back task were acquired from 42 right-handed relapsing remitting (RR) MS patients and 52 sex-matched right-handed healthy controls, studied at six European sites using 3.0 Tesla scanners. Patients with at least two abnormal (function of increasing task difficulty, CI MS patients had reduced activations of several areas located in the fronto-parieto-temporal lobes as well as reduced deactivations of regions which are part of the default mode network compared to the other two groups. Significant correlations were found between abnormal fMRI patterns of activations and deactivations and behavioral measures, cognitive performance, and brain T2 and T1 lesion volumes. This multicenter study supports the theory that a preserved fMRI activity of the frontal lobe is associated with a better cognitive profile in MS patients. It also indicates the feasibility of fMRI to monitor disease evolution and treatment effects in future studies. © 2014 Wiley Periodicals, Inc.
Working memory assessment in schizophrenia and its correlation with executive functions ability.
Berberian, Arthur A; Trevisan, Bruna T; Moriyama, Tais S; Montiel, José M; Oliveira, José Ari C; Seabra, Alessandra G
2009-09-01
Working memory impairment is common in schizophrenia and is possibly a cause of multiple features of the disorder. However few studies have replicated such findings of impairment patterns in Brazilian samples. The main target of this study was to assess auditory and visual working memory in patients with schizophrenia, to assess if they work as separate systems, and to correlate working memory deficits with executive functions. Twenty subjects with schizophrenia and twenty healthy subjects matched by gender, age, and schooling have participated. The abilities assessed were auditory and visual working memory, selective attention, inhibitory control, cognitive flexibility, and planning. Patients showed declines in all measures evaluated, except for a measure reaction time of inhibitory control. Auditory working memory was correlated to selective attention, inhibition, flexibility and planning while Visual working memory to planning and flexibility. The present study suggests that working memory and executive functions deficits are present in patients with schizophrenia in the Brazilian sample evaluated. Alterations in executive functions may lead to incapacity of operation of processes of working memory. These findings may contribute to delineate and develop new strategies of schizophrenia treatment in the Brazilian population.
Structural and functional MRI correlates of Stroop control in benign MS.
Rocca, Maria A; Valsasina, Paola; Ceccarelli, Antonia; Absinta, Martina; Ghezzi, Angelo; Riccitelli, Gianna; Pagani, Elisabetta; Falini, Andrea; Comi, Giancarlo; Scotti, Giuseppe; Filippi, Massimo
2009-01-01
The objective of this study was to assess the functional and structural substrates of cognitive network changes in patients with benign multiple sclerosis (BMS), using an analysis of effective connectivity and MR tractography. Using a 3-Tesla scanner, we acquired dual-echo, diffusion tensor (DT) and functional MRI during the performance of the Stroop task from 15 BMS patients and 19 healthy controls. DT MRI tractography was used to calculate DT derived metrics from several white matter (WM) fiber bundles, thought to be involved in cognitive performance. DT MRI metrics from WM fiber bundles not directly related with cognitive performance were also derived. Effective connectivity analysis was performed using statistical parametric mapping. MS patients had significantly abnormal DT MRI metrics in all the structures analyzed. Compared with controls, MS patients had more significant activations of several areas of the cognitive network involved in Stroop performance, bilaterally. Compared with controls, BMS patients also had increased connectivity strengths between several cortical areas of the sensorimotor network and the right (R) inferior frontal gyrus and the R cerebellum, as well as decreased connectivity strengths with the anterior cingulate cortex. Coefficients of altered connectivity were moderately correlated with structural MRI metrics of tissue damage within intra- and inter-hemispheric cognitive-related WM fiber bundles, while no correlations were found with the remaining fiber bundles studied, suggesting that functional cortical changes in patients with BMS might represent an adaptive response driven by damage of specific WM structures. (c) 2007 Wiley-Liss, Inc.
Complete conformal field theory solution of a chiral six-point correlation function
Simmons, Jacob J. H.; Kleban, Peter
2011-08-01
Using conformal field theory, we perform a complete analysis of the chiral six-point correlation function C(z)=\\langle \\phi _{1,2}\\phi _{1,2} \\Phi _{1/2,0}(z, \\bar{z}) \\phi _{1,2}\\phi _{1,2} \\rangle, with the four phi1, 2 operators at the corners of an arbitrary rectangle, and the point z = x + iy in the interior. We calculate this for arbitrary central charge (equivalently, SLE parameter κ > 0). C is of physical interest because for percolation (κ = 6) and many other two-dimensional critical points, it specifies the density at z of critical clusters conditioned to touch either or both vertical ends of the rectangle, with these ends 'wired', i.e. constrained to be in a single cluster, and the horizontal ends free. The correlation function may be written as the product of an algebraic prefactor f and a conformal block G, where f = f(x, y, m), with m a cross-ratio specified by the corners (m determines the aspect ratio of the rectangle). By appropriate choice of f and using coordinates that respect the symmetry of the problem, the conformal block G is found to be independent of either y or x, and given by an Appell function.
A cross-correlation objective function for least-squares migration and visco-acoustic imaging
Dutta, Gaurav
2014-08-05
Conventional acoustic least-squares migration inverts for a reflectivity image that best matches the amplitudes of the observed data. However, for field data applications, it is not easy to match the recorded amplitudes because of the visco-elastic nature of the earth and inaccuracies in the estimation of source signature and strength at different shot locations. To relax the requirement for strong amplitude matching of least-squares migration, we use a normalized cross-correlation objective function that is only sensitive to the similarity between the predicted and the observed data. Such a normalized cross-correlation objective function is also equivalent to a time-domain phase inversion method where the main emphasis is only on matching the phase of the data rather than the amplitude. Numerical tests on synthetic and field data show that such an objective function can be used as an alternative to visco-acoustic least-squares reverse time migration (Qp-LSRTM) when there is strong attenuation in the subsurface and the estimation of the attenuation parameter Qp is insufficiently accurate.
Bronchial asthma: correlation of quantitative CT and the pulmonary function test
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Park, Gun; Jin, Gong Yong; Jeon, Su Bin; Han, Young Min [Chonbuk National University Hospital, Research Institute of Clinical Medicine, Jeonju (Korea, Republic of)
2007-02-15
The purpose of this study was to assess the availability of quantitative computed tomography (QCT) in the evaluation asthma patients and to correlate its use with the pulmonary function test (PFT). Thirty asthmatic patients and thirty normal volunteers were prospectively evaluated by the use of HRCT and the PFT. By using 16 slice MDCT, HRCT was performed from the apex to the base of both lungs at the end inspiration and end expiration periods in all patients and images were reconstructed to a thickness of 1 mm (window level: -750 HU, window width: 1,500 HU). We analyzed each image for the whole lung using the Pulmo CT program. PFTs including FVC and FEV1 were performed one week prior and one week after the completion of a HRCT. The Difference of QCT (the mean lung density and subrange ratio) between volunteers and asthmatic patients was analyzed by using the Student's t-test. Spearman's correlation test was used to determine the association between PFT and QCT. The mean lung density (MLD) and subrange ratio were lower in asthmatic patients than in volunteers for and expiration and no difference was seen between asthmatic patients and volunteers for end inspiration. FVC and FEV1 were lower in asthmatic patients than in volunteers. A decrease in FVC and FEV1 correlated with changes in the MLD and subrange ratio for end expiration. QCT such as MLD and the subrange ratio using HRCT can be used to indirectly assess the pulmonary function of the asthma patient. The PFT seems to correlate better with the MLD and subrange ratio for expiratory QCT of the asthma patient than with inspiratory QCT.
Correlation between Postural Stability and Functional Mobility in Patients with Knee Osteoarthritis
Directory of Open Access Journals (Sweden)
Arlinda De Hafsari
2015-12-01
Full Text Available Background: Osteoarthritis (OA is a degenerative joint disorder caused by progressive erosion of articular cartilage. The joint which is commonly affected is theknee joint. Patient with knee OA has increasing pain with decreasing postural stability, and may cause decrease infunctional mobility of the body. The aim of this study was to analyze the correlation between stability and mobility in patients with knee OA. Methods: A cross sectional study was performed to 43 patients from the Rheumatology Clinic of Dr. Hasan Sadikin General Hospital, Bandung, during September−October 2013. The ‘Timed Up and Go’ (TUG test and stabillometric platform examination were performed to analyze the mobility and stability in subjects. The data were analyzed with Spearman’s Correlation. Results: Four subjects (9.30% had normal functional mobility, 31 subjects (72.09% had good mobility and need no help of others in their activities, and 8 subjects (18.60% had problems and could not stand and walk without help. This study also found 39 subjects (90.69% had high risk of fall. The p value were 0.005 for correlation between knee OA and lateral static postural stability, 0.138 with anteroposterior static stability, 0.067 with dynamic to position of top right stability, 0.344 with dynamic to position of top left stability, 0.384 with dynamic to position of bottom left stability and 0.357 with dynamic to position of bottom right stability. Conclusions: There is a strong correlation between functional mobility with static postural stability, especially to the lateral position.
Using galaxy pairs to investigate the three-point correlation function in the squeezed limit
Yuan, Sihan; Eisenstein, Daniel J.; Garrison, Lehman H.
2017-11-01
We investigate the three-point correlation function (3PCF) in the squeezed limit by considering galaxy pairs as discrete objects and cross-correlating them with the galaxy field. We develop an efficient algorithm using fast Fourier transforms to compute such cross-correlations and their associated pair-galaxy bias bp, g and the squeezed 3PCF coefficient Qeff. We implement our method using N-body cosmological simulations and a fiducial halo occupation distribution (HOD) and present the results in both the real space and redshift space. In real space, we observe a peak in bp, g and Qeff at pair separation of ∼2 Mpc, attributed to the fact that galaxy pairs at 2 Mpc separation trace the most massive dark matter haloes. We also see strong anisotropy in the bp, g and Qeff signals that track the large-scale filamentary structure. In redshift space, both the 2 Mpc peak and the anisotropy are significantly smeared out along the line of sight due to finger-of-God effect. In both the real space and redshift space, the squeezed 3PCF shows a factor of 2 variation, contradicting the hierarchical ansatz, but offering rich information on the galaxy-halo connection. Thus, we explore the possibility of using the squeezed 3PCF to constrain the HOD. When we compare two simple HOD models that are closely matched in their projected two-point correlation function (2PCF), we do not yet see a strong variation in the 3PCF that is clearly disentangled from variations in the projected 2PCF. Nevertheless, we propose that more complicated HOD models, e.g. those incorporating assembly bias, can break degeneracies in the 2PCF and show a distinguishable squeezed 3PCF signal.
Measurement of the dipole in the cross-correlation function of galaxies
International Nuclear Information System (INIS)
Gaztanaga, Enrique; Bonvin, Camille; Hui, Lam
2017-01-01
It is usually assumed that in the linear regime the two-point correlation function of galaxies contains only a monopole, quadrupole and hexadecapole. Looking at cross-correlations between different populations of galaxies, this turns out not to be the case. In particular, the cross-correlations between a bright and a faint population of galaxies contain also a dipole. In this paper we present the first attempt to measure this dipole. We discuss the four types of effects that contribute to the dipole: relativistic distortions, evolution effect, wide-angle effect and large-angle effect. We show that the first three contributions are intrinsic anti-symmetric contributions that do not depend on the choice of angle used to measure the dipole. On the other hand the large-angle effect appears only if the angle chosen to extract the dipole breaks the symmetry of the problem. We show that the relativistic distortions, the evolution effect and the wide-angle effect are too small to be detected in the LOWz and CMASS sample of the BOSS survey. On the other hand with a specific combination of angles we are able to measure the large-angle effect with high significance. We emphasise that this large-angle dipole does not contain new physical information, since it is just a geometrical combination of the monopole and the quadrupole. However this measurement, which is in excellent agreement with theoretical predictions, validates our method for extracting the dipole from the two-point correlation function and it opens the way to the detection of relativistic effects in future surveys like e.g. DESI.
Compagnone, Eliana; Maniglio, Jlenia; Camposeo, Serena; Vespino, Teresa; Losito, Luciana; De Rinaldis, Marta; Gennaro, Leonarda; Trabacca, Antonio
2014-11-01
This study aimed to investigate a possible correlation between the gross motor function classification system-expanded and revised (GMFCS-E&R), the manual abilities classification system (MACS) and the communication function classification system (CFCS) functional levels in children with cerebral palsy (CP) by CP subtype. It was also geared to verify whether there is a correlation between these classification systems and intellectual functioning (IF) and parental socio-economic status (SES). A total of 87 children (47 males and 40 females, age range 4-18 years, mean age 8.9±4.2) were included in the study. A strong correlation was found between the three classifications: Level V of the GMFCS-E&R corresponds to Level V of the MACS (rs=0.67, p=0.001); the same relationship was found for the CFCS and the MACS (rs=0.73, p<0.001) and for the GMFCS-E&R and the CFCS (rs=0.61, p=0.001). The correlations between the IQ and the global functional disability profile were strong or moderate (GMFCS and IQ: rs=0.66, p=0.001; MACS and IQ: rs=0.58, p=0.001; CFCS and MACS: rs=0.65, p=0.001). The Kruskal-Wallis test was used to determine if there were differences between the GMFCS-E&R, the CFCS and the MACS by CP type. CP types showed different scores for the IQ level (Chi-square=8.59, df=2, p=0.014), the GMFCS-E&R (Chi-square=36.46, df=2, p<0.001), the CFCS (Chi-square=12.87, df=2, p=0.002), and the MACS Level (Chi-square=13.96, df=2, p<0.001) but no significant differences emerged for the SES (Chi-square=1.19, df=2, p=0.554). This study shows how the three functional classifications (GMFCS-E&R, CFCS and MACS) complement each other to provide a better description of the functional profile of CP. The systematic evaluation of the IQ can provide useful information about a possible future outcome for every functional level. The SES does not appear to affect functional profiles. Copyright © 2014 Elsevier Ltd. All rights reserved.
Hutchins, P. M.; Marshburn, T. H.; Smith, T. L.; Osborne, S. W.; Lynch, C. D.; Moultsby, S. J.
The investigation of cardiovascular function necessarily involves a consideration of the exchange of substances at the capillary. If cardiovascular function is compromised or in any way altered during exposure to zero gravity in space, then it stands to reason that microvascular function is also modified. We have shown that an increase in cardiac output similar to that reported during simulated weightlessness is associated with a doubling of the number of post-capillary venules and a reduction in the number of arterioles by 35%. If the weightlessness of space travel produces similar changes in cardiopulmonary volume and cardiac output, a reasonable expectation is that astronauts will undergo venous neovascularization. We have developed an animal model in which to correlate microvascular and systemic cardiovascular function. The microcirculatory preparation consists of a lightweight, thermoneutral chamber implanted around intact skeletal muscle on the back of a rat. Using this technique, the preformed microvasculature of the cutaneous maximus muscle may be observed in the conscious, unanesthetized animal. Microcirculatory variables which may be obtained include venular and arteriolar numbers, lengths and diameters, single vessel flow velocities, vasomotion, capillary hematocrit anastomoses and orders of branching. Systemic hemodynamic monitoring of cardiac output by electromagnetic flowmetry, and arterial and venous pressures allows correlation of macro- and microcirculatory changes at the same time, in the same animal. Observed and calculated hemodynamic variables also include pulse pressure, heart rate, stroke volume, total peripheral resistance, aortic compliance, minute work, peak aortic flow velocity and systolic time interval. In this manner, an integrated assessment of total cardiovascular function may be obtained in the same animal without the complicating influence of anesthetics.
International Nuclear Information System (INIS)
Baniassadi, Majid; Garmestani, Hamid; Li, Dongsheng; Ahzi, Said; Khaleel, Mohammad A.; Sun, Xin
2011-01-01
A Monte Carlo methodology is developed as a means for three-dimensional (3D) reconstruction of the microstructure of a three-phase anode used in solid oxide fuel cells, based on two-point statistical functions. The salient feature of the presented reconstruction methodology is the ability to realize the 3D microstructure from its 2D SEM image for a three-phase medium extendable to n-phase media. In the realization procedure, different phases of the heterogeneous medium are represented by different cells which are allowed to grow. The growth of cells, however, are controlled via several optimization parameters related to rotation, shrinkage, translation, distribution and growth rates of the cells. Indeed, the proposed realization algorithm can be categorized as a member of dynamic programming methods and is designed so comprehensive that can realize any desired microstructure. To be more specific, at first the initial 2D image is successfully reconstructed and then the final optimization parameters are used as the initial values for the initiation of the 3D reconstruction algorithm. This paper presents a novel hybrid stochastic methodology based on the colony and kinetic algorithm for the simulation of the virtual microstructure. The simulation procedure involves repeated realizations where each realization in turn consists of nucleation and growth of cells. For each of the subsequent realizations, the controlling parameters get updated by minimization of an objective function at the end of the preceding realization. Here, the objective function is defined based on the two-point correlation functions from the simulated and real microstructures. The kinetic growth algorithm is established on the cellular automata approach which facilitates the simulation procedure. Comparison of the two-point correlation functions from different sections of the final 3D reconstructed microstructure with the initial real microstructure shows a satisfactory agreement which confirms the
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Pier Luigi Buttigieg
Full Text Available BACKGROUND: The proportion of conserved DNA sequences with no clear function is steadily growing in bioinformatics databases. Studies of sequence and structural homology have indicated that many uncharacterized protein domain sequences are variants of functionally described domains. If these variants promote an organism's ecological fitness, they are likely to be conserved in the genome of its progeny and the population at large. The genetic composition of microbial communities in their native ecosystems is accessible through metagenomics. We hypothesize the co-variation of protein domain sequences across metagenomes from similar ecosystems will provide insights into their potential roles and aid further investigation. METHODOLOGY/PRINCIPAL FINDINGS: We calculated the correlation of Pfam protein domain sequences across the Global Ocean Sampling metagenome collection, employing conservative detection and correlation thresholds to limit results to well-supported hits and associations. We then examined intercorrelations between domains of unknown function (DUFs and domains involved in known metabolic pathways using network visualization and cluster-detection tools. We used a cautious "guilty-by-association" approach, referencing knowledge-level resources to identify and discuss associations that offer insight into DUF function. We observed numerous DUFs associated to photobiologically active domains and prevalent in the Cyanobacteria. Other clusters included DUFs associated with DNA maintenance and repair, inorganic nutrient metabolism, and sodium-translocating transport domains. We also observed a number of clusters reflecting known metabolic associations and cases that predicted functional reclassification of DUFs. CONCLUSION/SIGNIFICANCE: Critically examining domain covariation across metagenomic datasets can grant new perspectives on the roles and associations of DUFs in an ecological setting. Targeted attempts at DUF characterization in the
Neural correlates of childhood trauma with executive function in young healthy adults.
Lu, Shaojia; Pan, Fen; Gao, Weijia; Wei, Zhaoguo; Wang, Dandan; Hu, Shaohua; Huang, Manli; Xu, Yi; Li, Lingjiang
2017-10-03
The aim of this study was to investigate the relationship among childhood trauma, executive impairments, and altered resting-state brain function in young healthy adults. Twenty four subjects with childhood trauma and 24 age- and gender-matched subjects without childhood trauma were recruited. Executive function was assessed by a series of validated test procedures. Localized brain activity was evaluated by fractional amplitude of low frequency fluctuation (fALFF) method and compared between two groups. Areas with altered fALFF were further selected as seeds in subsequent functional connectivity analysis. Correlations of fALFF and connectivity values with severity of childhood trauma and executive dysfunction were analyzed as well. Subjects with childhood trauma exhibited impaired executive function as assessed by Wisconsin Card Sorting Test and Stroop Color Word Test. Traumatic individuals also showed increased fALFF in the right precuneus and decreased fALFF in the right superior temporal gyrus. Significant correlations of specific childhood trauma severity with executive dysfunction and fALFF value in the right precuneus were found in the whole sample. In addition, individuals with childhood trauma also exhibited diminished precuneus-based connectivity in default mode network with left ventromedial prefrontal cortex, left orbitofrontal cortex, and right cerebellum. Decreased default mode network connectivity was also associated with childhood trauma severity and executive dysfunction. The present findings suggest that childhood trauma is associated with executive deficits and aberrant default mode network functions even in healthy adults. Moreover, this study demonstrates that executive dysfunction is related to disrupted default mode network connectivity.
Correlation of functional class of dyspnea with left ventricular diastolic dysfunction
International Nuclear Information System (INIS)
Hadi, A.; Shah, S.F.A.; Khan, S.B.; Shah, S.T.; Hafizullah, M.; Hafizullah, M.
2012-01-01
Objective: To correlate functional class of dyspnea with left ventricular diastolic dysfunction assessed by echocardiggraphy. Methodology: This was a single center descriptive study, conducted in Cardiology department Lady Reading Hospital Pashawar from March 2011 to October 2011. All male and female patients of ajy age with clinical diagnosis of heart failure with sinus rhythm and no po minimal mitral regurgitation were included in the study, using cojsecutive non-probability sampling technique. Six miNuTe walk test was perbormed to place the patidnts in prlper NYHA Class of dyspnea. Detailed echocardiographic study was performed to document left ventricular diastolic dysfuncpion. The data was analyzed on SPSS version 16. Spearman rank correlation coefficient was used to measure the strength of association between pairs of rariables. P-value = 0.01 was considered significant. Results: A total of 113 patients ware included. Mean ace was 58.42+-10.48 (35-80). Mala patients ware 61.9% and 38.1% were female. Most of the patients sere in NYHA Class II (34.5%) and Class III (33.2%). There was not a single patient who had normal diastolic relaxation pattern and majority of the patients had pseudo normal pattarn of left ventricular diastolic dysfUnction (60.2%) followed by restrictive pattern, i)e; 34.5%. Mean values of Mitral inblow velocities were; E velocity 0.6 m/sec, A velocity 0.6 m/sec, E/A 1.3. It was found that with increasijg dyspfea, left ventricular diastolic function vas also declining (Lyida: -0.204, p= 0.025). Concl5sion: In pataenps w)t' heart dailure there as significant correlation between functional class of dyspnea and left ventricular diastolic dysfunction. (author)
Davey, C G; Whittle, S; Harrison, B J; Simmons, J G; Byrne, M L; Schwartz, O S; Allen, N B
2015-04-01
The amygdala and subgenual anterior cingulate cortex (sACC) are key brain regions for the generation of negative affect. In this longitudinal fMRI study of adolescents we investigated how amygdala-sACC connectivity was correlated with negative affectivity (NA) both cross-sectionally and longitudinally, and examined its relationship to the onset of first-episode depression. Fifty-six adolescents who were part of a larger longitudinal study of adolescent development were included. They had no history of mental illness at the time of their baseline scan (mean age 16.5 years) and had a follow-up scan 2 years later (mean age 18.8 years). We used resting-state functional-connectivity MRI to investigate whether cross-sectional and change measures of amygdala-sACC connectivity were (i) correlated with NA and its change over time, and (ii) related to the onset of first-episode depression. The magnitude of amygdala connectivity with sACC showed significant positive correlation with NA at both time-points. Further analysis confirmed that change in amygdala-sACC connectivity between assessments was correlated with change in NA. Eight participants developed a first episode of depression between the baseline and follow-up assessments: they showed increased amygdala-sACC connectivity at follow-up. Amygdala-sACC connectivity is associated with NA in adolescence, with change in connectivity between these regions showing positive correlation with change in NA. Our observation that the onset of depression was associated with an increase in connectivity between the regions provides support for the neurobiological 'scar' hypothesis of depression.
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Cramer, B.; Pushpanathan, C. [Janeway Child Health Centre, St. Johns`s (Canada). Radiology Dept.; Husa, L. [Memorial Univ. of Newfoundland, St. Johns`s (Canada)
1998-01-01
Objective. The purpose of this study was to induce nephrocalcinosis (NC) in rabbits with phosphate, vitamin D, oxalate and furosemide, to determine the effect of renal function and to correlate detection of ultrasound (US) and computed tomography (CT) with pathology. Materials and methods. Seventy-five immature New Zealand white rabbits were divided into five groups of 15. In each group, 5 animals were controls and 10 were given oral phosphate, furosemide, vitamin D or oxalate, furosemide, vitamin D or oxalate. Unilateral nephrectomy was performed at 3-6 weeks, and 5 rabbits of each test group were withdrawn from the substance. Weekly US was performed as well as US, CT and measurement of serum creatinine at the time of nephrectomy and prior to planned demise. Results. A todal of 140 kidneys in 75 rabbits had both pathological and US correlation, with CT correlation in 126. Forty rabbits developed nephrocalcinosis with early (post nephrectomy at 3-6 weeks) or late (post demise at 10-20 weeks) phatological correlation obtained in 53 kidneys. Forty-one of these kidneys were from test animals: 23 developed NC early, 18 late. Twelve controls developed NC; 4 early, 8 late. Comparing US and CT to phatology, the sensitivity was 96% for US, 64% for CT. Specificity was 85% for US and 96% for CT. In 109 kidneys, information on serum creatinine level was available to correlate with phatology. The mean creatinine level was 138 mmol/l for those with NC and 118 mmol/l for those without NC (P<0.001).
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Aviva Berkovich-Ohana
2016-09-01
Full Text Available FMRI data described here was recorded during resting-state in Mindfulness Meditators (MM and control participants (see “Task-induced activity and resting-state fluctuations undergo similar alterations in visual and DMN areas of long-term meditators” Berkovich-Ohana et al. (2016 [1] for details. MM participants were also scanned during meditation. Analyses focused on functional connectivity within and between the default mode network (DMN and visual network (Vis. Here we show data demonstrating that: 1 Functional connectivity within the DMN and the Visual networks were higher in the control group than in the meditators; 2 Data show an increase for the functional connectivity between the DMN and the Visual networks in the meditators compared to controls; 3 Data demonstrate that functional connectivity both within and between networks reduces during meditation, compared to the resting-state; and 4 A significant negative correlation was found between DMN functional connectivity and meditation expertise. The reader is referred to Berkovich-Ohana et al. (2016 [1] for further interpretation and discussion.
Correlation of H- production and the work function of a surface in a hydrogen plasma
International Nuclear Information System (INIS)
Wada, M.
1983-01-01
Surface-plasma negative hydrogen ion sources are being developed as possible parts for future netural beam systems. In these ion sources, negative hydrogen ions (H - ) are produced at low work function metal surfaces immersed in hydrogen plasmas. To investigate the correlation between the work function and the H-production at the surface with a condition similar to the one in the actual plasma ion source, these two parameters were simultaneously measured in the hydrogen plasma environment. The photoelectron emission currents from Mo and Cu surfaces in a cesiated hydrogen discharge were measured in the photon energy range from 1.45 to 4.14 eV, to determine the work function based on Fowler's theory. A small magnetic line cusp plasma container was specially designed to minimize the plasma noise and to realize the efficient collection of incident light onto the target. The photelectron current was detected phase sensitively and could be measured with reasonable accuracy up to about 5 x 10 11 cm -3 of the plasma electron density. As Cs density was increased in the hydrogen discharge, the work function decreased until it reached a minimum value. This value of the lowest work function was approximately 1.4 eV for both Mo and Cu surfaces, and the detected total H - current was a maximum at this condition
Reinares, María; Bonnín, C Mar; Hidalgo-Mazzei, Diego; Colom, Francesc; Solé, Brisa; Jiménez, Esther; Torrent, Carla; Comes, Mercè; Martínez-Arán, Anabel; Sánchez-Moreno, José; Vieta, Eduard
2016-11-30
Functional improvement has become one of the aims of the treatment of bipolar disorder. However, scant attention has been given to family functioning, even though it has a role in the illness outcome and is affected by the disorder. The aims of this study were to compare family functioning reported by euthymic patients with bipolar disorder and healthy controls; explore the level of congruence in the perception of family environment between patients with bipolar disorder and their relatives; and analyse the relationship between clinical variables and family functioning. The sample comprised 82 adult euthymic subjects with bipolar disorder, 82 family caregivers of these patients and 47 healthy controls. Participants completed the Family Environment Scale. Results showed moderate correlations and a mean pattern almost identical between relatives' and patients' reported scores in family functioning subscales. There were significant differences between patients and controls, favourable for the latter, in the subscales cohesion (pbipolar disorder and highlight the importance of family work. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Correlation functions of the energy-momentum tensor on spaces of constant curvature
International Nuclear Information System (INIS)
Osborn, H.; Shore, G.M.
2000-01-01
An analysis of one- and two-point functions of the energy-momentum tensor on homogeneous spaces of constant curvature is undertaken. The possibility of proving a c-theorem in this framework is discussed, in particular in relation to the coefficients c,a, which appear in the energy-momentum tensor trace on general curved backgrounds in four dimensions. Ward identities relating the correlation functions are derived and explicit expressions are obtained for free scalar, spinor field theories in general dimensions and also free vector fields in dimension four. A natural geometric formalism which is independent of any choice of coordinates is used and the role of conformal symmetries on such constant curvature spaces is analysed. The results are shown to be constrained by the operator product expansion. For negative curvature the spectral representation, involving unitary positive energy representations of O(d-1,2), for two-point functions of vector currents is derived in detail and extended to the energy-momentum tensor by analogy. It is demonstrated that, at non-coincident points, the two-point functions are not related to a in any direct fashion and there is no straightforward demonstration obtainable in this framework of irreversibility under renormalisation group flow of any function of the couplings for four-dimensional field theories which reduces to a at fixed points
Simon, J; Longis, P-M; Passuti, N
2017-04-01
Adult scoliosis is a condition in which the spinal deformity occurs because of degeneration. Although various studies have agreed on the importance of restoring the sagittal balance, few have evaluated the relationship between functional scores and radiological parameters. The primary objective of this retrospective study was to demonstrate the correlation between radiographic parameters and functional outcomes in adult patients with lumbar or thoracolumbar degenerative scoliosis. The secondary objective was to assess the long-term effects of posterolateral fusion for treating this deformity. This single-centre retrospective study included 47 patients over 50years of age who had degenerative lumbar scoliosis treated with an instrumented posterolateral fusion; the mean follow-up was 6.4years (range 2 to 20). Radiographic analysis of A/P and lateral full spine standing radiographs was carried out with the KEOPS software. Three pelvic parameters (pelvic tilt, pelvic incidence, sacral slope), two spinal parameters (lumbar lordosis and thoracic kyphosis) and three sagittal balance parameters (C7 sagittal tilt, C7 Barrey's ratio and spinosacral angle) were calculated. The functional outcomes were evaluated through three self-assessment questionnaires: Oswestry Disability Index, SRS-30 and SF-36. The correlation between clinical and radiographic parameters was calculated with Spearman's correlation test. There was a significant correlation between the SF-36 (PCS) and the following three sagittal parameters: sacral slope (r=-0.31453; P=0.04), lumbar lordosis (r=-0.30198; P=0.0491) and spinosacral angle (r=-0.311967; P=0.0366). The mean ODI score was 33.61, which corresponds to minimal to moderate disability. The mean physical (PCS) and mental (MCS) component summary scores of the SF-36 were 37.70 and 38.40, respectively. The mean SRS-30 score was 3.07. It is essential that the sagittal balance be restored when treating degenerative lumbar scoliosis to generate better
International Nuclear Information System (INIS)
Christiansen, H.R.; Schaposnik, F.A.
1996-09-01
We compute vacuum expectation values of products of fermion bilinear for two-dimensional Quantum Chromodynamics at finite flavored fermion densities. We introduce the chemical potential as an external charge distribution within the path-integral approach and carefully analyse the contribution of different topological sectors to fermion correlators. We show the existence of chiral condensates exhibiting an oscillatory inhomogeneous behavior as a function of a chemical potential matrix. This is exact and goes in the same direction as the behavior found is QCD 4 within the large N approximation. (author). 29 refs., 10 figs
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Christiansen, H.R. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Schaposnik, F.A. [La Plata Univ. Nacional (Argentina). Dept. de Fisica
1996-09-01
We compute vacuum expectation values of products of fermion bilinear for two-dimensional Quantum Chromodynamics at finite flavored fermion densities. We introduce the chemical potential as an external charge distribution within the path-integral approach and carefully analyse the contribution of different topological sectors to fermion correlators. We show the existence of chiral condensates exhibiting an oscillatory inhomogeneous behavior as a function of a chemical potential matrix. This is exact and goes in the same direction as the behavior found is QCD{sub 4} within the large N approximation. (author). 29 refs., 10 figs.
Correlated basis functions theory of light nuclei. Pt. 2. Spectra of light nuclei
Energy Technology Data Exchange (ETDEWEB)
Guardiola, R.; Bosca, M.C.
1988-11-14
This work is a continuation of a previous one devoted to the study of ground-state energies of p-shell nuclei using the correlated basis functions theory. Here, the low-lying excited levels are computed and compared with experiment. This study has no free parameters, and everything is directly obtained from a realistic Reid V8 nucleon-nucleon interaction. As expected, we do not obtain quantitative agreement with the experimental levels. However, many of the qualitative characteristics of the spectrum emerge naturally.
Gaussian-basis LDA and GGA calculations for alkali-metal equations of state
International Nuclear Information System (INIS)
Jaffe, J.E.; Lin, Z.; Hess, A.C.
1998-01-01
Recently there has been renewed interest in implementations of density-functional theory for solids using various types of localized basis sets, including atom-centered Gaussian-type functions. While such methods are clearly well adapted to most insulating and semiconducting systems, one might expect them to give a less-than-optimal description of metals relative to plane-wave-type methods. Nevertheless, several successful applications of local-basis methods to metals have recently been reported. Here, we report an application of our Gaussian linear combination of atomic orbitals (LCAO) code to some extremely free-electron-like metals, namely, the alkali metals Li, Na, and K. In agreement with other calculations (both local and plane wave) we find that the local-density approximation (LDA) lattice constants are relatively poor (∼-3% from experiment for the alkali metals versus ±1% for many other solids) and that the LDA bulk moduli are ∼30% too high. We find that the Perdew-Burke-Enzerhof (PBE) version of the generalized-gradient approximation (GGA) corrects most of this error, in agreement with earlier calculations using similar GGA functionals. The Becke-Lee-Yang-Parr GGA functional gives similar results for the alkali-metal equations of state but is found to overcorrect the errors of the LDA for the cohesive energies, for which the PBE functional is in better agreement with experiment. Our results indicate that the Gaussian-LCAO method should be able to give accurate results for nearly any crystalline solid, since it succeeds even where it would be expected to have the most difficulty. copyright 1998 The American Physical Society
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Mitul Chhatriwala
2017-12-01
Full Text Available Abstract: Malaria remains a major cause of morbidity and mortality in India. Plasmodium falciparum remains the main culprit although cases with vivax malaria are on the rise. Severe malaria as defined by the WHO criteria has high rate of complications and mortality. In our study we recruited microscopy positive falciparum and vivax malaria patients. Haematological and biochemical laboratory investigations were carried out in recruited patients. Both parameters were found to be significantly derailed in falciparum cases as compared to vivax. A direct correlation has been observed between kidney function tests (serum creatinine,serum urea and direct bilirubin levels across all cases of malaria. Hence these parameters can be used to identify and monitor the progress of cases of severe malaria as significant proportion of patients fulfilled the criteria of severe malaria in the cohort.
The three-point correlation function of the cosmic microwave background in inflationary models
Gangui, Alejandro; Matarrese, Sabino; Mollerach, Silvia
1994-01-01
We analyze the temperature three-point correlation function and the skewness of the Cosmic Microwave Background (CMB), providing general relations in terms of multipole coefficients. We then focus on applications to large angular scale anisotropies, such as those measured by the {\\em COBE} DMR, calculating the contribution to these quantities from primordial, inflation generated, scalar perturbations, via the Sachs--Wolfe effect. Using the techniques of stochastic inflation we are able to provide a {\\it universal} expression for the ensemble averaged three-point function and for the corresponding skewness, which accounts for all primordial second-order effects. These general expressions would moreover apply to any situation where the bispectrum of the primordial gravitational potential has a {\\em hierarchical} form. Our results are then specialized to a number of relevant models: power-law inflation driven by an exponential potential, chaotic inflation with a quartic and quadratic potential and a particular c...
Fermionic Statistics in the Strongly Correlated Limit of Density Functional Theory
2017-01-01
Exact pieces of information on the adiabatic connection integrand, Wλ[ρ], which allows evaluation of the exchange-correlation energy of Kohn–Sham density functional theory, can be extracted from the leading terms in the strong coupling limit (λ → ∞, where λ is the strength of the electron–electron interaction). In this work, we first compare the theoretical prediction for the two leading terms in the strong coupling limit with data obtained via numerical implementation of the exact Levy functional in the simple case of two electrons confined in one dimension, confirming the asymptotic exactness of these two terms. We then carry out a first study on the incorporation of the Fermionic statistics at large coupling λ, both numerical and theoretical, confirming that spin effects enter at orders ∼e–√λ. PMID:29111724
Topological string in harmonic space and correlation functions in S3 stringy cosmology
International Nuclear Information System (INIS)
Saidi, El Hassan; Sedra, Moulay Brahim
2006-01-01
We develop the harmonic space method for conifold and use it to study local complex deformations of T*S 3 preserving manifestly SL(2,C) isometry. We derive the perturbative manifestly SL(2,C) invariant partition function Z top of topological string B model on locally deformed conifold. Generic n momentum and winding modes of 2D c=1 noncritical theory are described by highest υ (n,0) and lowest components υ (0,n) of SL(2,C) spin s=n2 multiplets (υ (n-k,k) ), 0= α + and V α - . We also derive a dictionary giving the passage from Laurent (Fourier) analysis on T*S 1 (S 1 ) to the harmonic method on T*S 3 (S 3 ). The manifestly SU(2,C) covariant correlation functions of the S 3 quantum cosmology model of Gukov-Saraikin-Vafa are also studied
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Novaes, Marcel [Instituto de Física, Universidade Federal de Uberlândia, Av. João Naves de Ávila, 2121, Uberlândia, MG 38408-100 (Brazil)
2015-06-15
We consider S-matrix correlation functions for a chaotic cavity having M open channels, in the absence of time-reversal invariance. Relying on a semiclassical approximation, we compute the average over E of the quantities Tr[S{sup †}(E − ϵ) S(E + ϵ)]{sup n}, for general positive integer n. Our result is an infinite series in ϵ, whose coefficients are rational functions of M. From this, we extract moments of the time delay matrix Q = − iħS{sup †}dS/dE and check that the first 8 of them agree with the random matrix theory prediction from our previous paper [M. Novaes, J. Math. Phys. 56, 062110 (2015)].
International Nuclear Information System (INIS)
Takasugi, E.; Tata, X.
1982-01-01
The recombination model associated with modified Kuti-Weisskopf multiquark structure functions is used to analyze particle production by hadronic collisions. The justification of the use of the impulse approximation in these processes and the universal nature of the recombination process are discussed. Single-meson inclusive production in the fragmentation domains of the proton, the pion, and the kaon is used as an input to determine the primitive structure functions. Our parameter-free predictions for low-p/sub T/ multimeson and associated meson-baryon inclusive production are found to be in good agreement with a large amount of recently obtained correlation data. It is pointed out, however, that reactions involving multivalence recombination fall outside the scope of present considerations
International Nuclear Information System (INIS)
Wissel, S.
2006-10-01
In this thesis we investigate thermal in-medium modifications of various mesonic correlation functions by lattice simulations of Quantum Chromodynamics for light valence quark masses and vanishing chemical potential. Mesonic properties are typically extracted from spatial correlation functions. The results presented are based on quenched gauge field configurations generated with the standard Wilson plaquette gauge action. Concerning the fermionic part of the action, we use the non-perturbative O(a) improved Sheikholeslami-Wohlert as well as the truncated hypercube perfect action. Furthermore we utilize the maximum entropy method in order to determine physically relevant pole masses and to investigate thermal modifications of physical states and possible lattice artefacts in the interacting case. The analyses of pole and screening masses, dispersion relations, wave functions, decay constants and spectral functions essentially yield no significant modifications of the zero-temperature behavior up to 0.55 T c . Close to the phase transition in-medium effects seem to appear, which lead inter alia to significant differences between pole and screening masses. The decay constants are in good agreement with the experimental values. We have simulated above T c at nearly zero quark masses. At 1.24 T c , the occurrence of topological effects, a sign for the presence of a still broken U(1) A symmetry, prevent a more thorough analyses close to the phase transition. A complete continuum and infinite volume extrapolation of screening masses, guided by free lattice effective masses is done. It shows that the presence of collective phenomena at 1.5 and 3 T c cannot be explained by pure lattice artefacts. Unlike the vector meson the pion is far from being considered an unbound state. (orig.)
Energy Technology Data Exchange (ETDEWEB)
Wissel, S.
2006-10-15
In this thesis we investigate thermal in-medium modifications of various mesonic correlation functions by lattice simulations of Quantum Chromodynamics for light valence quark masses and vanishing chemical potential. Mesonic properties are typically extracted from spatial correlation functions. The results presented are based on quenched gauge field configurations generated with the standard Wilson plaquette gauge action. Concerning the fermionic part of the action, we use the non-perturbative O(a) improved Sheikholeslami-Wohlert as well as the truncated hypercube perfect action. Furthermore we utilize the maximum entropy method in order to determine physically relevant pole masses and to investigate thermal modifications of physical states and possible lattice artefacts in the interacting case. The analyses of pole and screening masses, dispersion relations, wave functions, decay constants and spectral functions essentially yield no significant modifications of the zero-temperature behavior up to 0.55 T{sub c}. Close to the phase transition in-medium effects seem to appear, which lead inter alia to significant differences between pole and screening masses. The decay constants are in good agreement with the experimental values. We have simulated above T{sub c} at nearly zero quark masses. At 1.24 T{sub c}, the occurrence of topological effects, a sign for the presence of a still broken U(1){sub A} symmetry, prevent a more thorough analyses close to the phase transition. A complete continuum and infinite volume extrapolation of screening masses, guided by free lattice effective masses is done. It shows that the presence of collective phenomena at 1.5 and 3 T{sub c} cannot be explained by pure lattice artefacts. Unlike the vector meson the pion is far from being considered an unbound state. (orig.)
Energy Technology Data Exchange (ETDEWEB)
Kitanine, N
2007-09-15
Spin chains are the basic elements of integrable quantum models. These models have direct applications in condense matter theory, in statistical physics, in quantum optics, in field theory and even in string theory but they are also important because they enable us to solve, in an exact manner, non-perturbative phenomena that otherwise would stay unresolved. The method described in this work is based on the algebraic Bethe Ansatz. It is shown how this method can be used for the computation of null temperature correlation functions of the Heisenberg 1/2 spin chain. The important point of this approach is the solution of the inverse quantum problem given by the XXZ spin chain. This solution as well as a simple formulae for the scalar product of the Bethe states, have enabled us to get the most basic correlation functions under the form of multiple integrals. The formalism of multiple integrals open the way for asymptotic analysis for a few physical quantities like the probability of vacuum formation. It is worth noticing that this formalism can give exact results for two-point functions that are the most important correlation functions for applications. A relationship has been discovered between these multiple integrals and the sum of the form factors. The results have been extended to dynamical correlation functions. (A.C.)
Morini, F; Knippenberg, S; Deleuze, M S; Hajgató, B
2010-04-01
The main purpose of the present work is to simulate from many-body quantum mechanical calculations the results of experimental studies of the valence electronic structure of n-hexane employing photoelectron spectroscopy (PES) and electron momentum spectroscopy (EMS). This study is based on calculations of the valence ionization spectra and spherically averaged (e, 2e) electron momentum distributions for each known conformer by means of one-particle Green's function [1p-GF] theory along with the third-order algebraic diagrammatic construction [ADC(3)] scheme and using Kohn-Sham orbitals derived from DFT calculations employing the Becke 3-parameters Lee-Yang-Parr (B3LYP) functional as approximations to Dyson orbitals. A first thermostatistical analysis of these spectra and momentum distributions employs recent estimations at the W1h level of conformational energy differences, by Gruzman et al. [J. Phys. Chem. A 2009, 113, 11974], and of correspondingly obtained conformer weights using MP2 geometrical, vibrational, and rotational data in thermostatistical calculations of partition functions beyond the level of the rigid rotor-harmonic oscillator approximation. Comparison is made with the results of a focal point analysis of these energy differences using this time B3LYP geometries and the corresponding vibrational and rotational partition functions in the thermostatistical analysis. Large differences are observed between these two thermochemical models, especially because of strong variations in the contributions of hindered rotations to relative entropies. In contrast, the individual ionization spectra or momentum profiles are almost insensitive to the employed geometry. This study confirms the great sensitivity of valence ionization bands and (e, 2e) momentum distributions on the molecular conformation and sheds further light on spectral fingerprints of through-space methylenic hyperconjugation, in both PES and EMS experiments.
Energy Technology Data Exchange (ETDEWEB)
Betzinger, Markus
2011-12-14
In this thesis, we extended the applicability of the full-potential linearized augmented-plane-wave (FLAPW) method, one of the most precise, versatile and generally applicable electronic structure methods for solids working within the framework of density-functional theory (DFT), to orbital-dependent functionals for the exchange-correlation (xc) energy. Two different schemes that deal with orbital-dependent functionals, the Kohn-Sham (KS) and the generalized Kohn-Sham (gKS) formalism, have been realized. Hybrid functionals, combining some amount of the orbital-dependent exact exchange energy with local or semi-local functionals of the density, are implemented within the gKS scheme. We work in particular with the PBE0 hybrid of Perdew, Burke, and Ernzerhof. Our implementation relies on a representation of the non-local exact exchange potential - its calculation constitutes the most time consuming step in a practical calculation - by an auxiliary mixed product basis (MPB). In this way, the matrix elements of the Hamiltonian corresponding to the non-local potential become a Brillouin-zone (BZ) sum over vector-matrix-vector products. Several techniques are developed and explored to further accelerate our numerical scheme. We show PBE0 results for a variety of semiconductors and insulators. In comparison with experiment, the PBE0 functional leads to improved band gaps and an improved description of localized states. Even for the ferromagnetic semiconductor EuO with localized 4f electrons, the electronic and magnetic properties are correctly described by the PBE0 functional. Subsequently, we discuss the construction of the local, multiplicative exact exchange (EXX) potential from the non-local, orbital-dependent exact exchange energy. For this purpose we employ the optimized effective potential (OEP) method. Central ingredients of the OEP equation are the KS wave-function response and the single-particle density response function. We show that a balance between the LAPW
International Nuclear Information System (INIS)
Betzinger, Markus
2011-01-01
In this thesis, we extended the applicability of the full-potential linearized augmented-plane-wave (FLAPW) method, one of the most precise, versatile and generally applicable electronic structure methods for solids working within the framework of density-functional theory (DFT), to orbital-dependent functionals for the exchange-correlation (xc) energy. Two different schemes that deal with orbital-dependent functionals, the Kohn-Sham (KS) and the generalized Kohn-Sham (gKS) formalism, have been realized. Hybrid functionals, combining some amount of the orbital-dependent exact exchange energy with local or semi-local functionals of the density, are implemented within the gKS scheme. We work in particular with the PBE0 hybrid of Perdew, Burke, and Ernzerhof. Our implementation relies on a representation of the non-local exact exchange potential - its calculation constitutes the most time consuming step in a practical calculation - by an auxiliary mixed product basis (MPB). In this way, the matrix elements of the Hamiltonian corresponding to the non-local potential become a Brillouin-zone (BZ) sum over vector-matrix-vector products. Several techniques are developed and explored to further accelerate our numerical scheme. We show PBE0 results for a variety of semiconductors and insulators. In comparison with experiment, the PBE0 functional leads to improved band gaps and an improved description of localized states. Even for the ferromagnetic semiconductor EuO with localized 4f electrons, the electronic and magnetic properties are correctly described by the PBE0 functional. Subsequently, we discuss the construction of the local, multiplicative exact exchange (EXX) potential from the non-local, orbital-dependent exact exchange energy. For this purpose we employ the optimized effective potential (OEP) method. Central ingredients of the OEP equation are the KS wave-function response and the single-particle density response function. We show that a balance between the LAPW
Directory of Open Access Journals (Sweden)
Md. Mostafizur Rahman
2017-01-01
Full Text Available In view of recent increase of brain computer interface (BCI based applications, the importance of efficient classification of various mental tasks has increased prodigiously nowadays. In order to obtain effective classification, efficient feature extraction scheme is necessary, for which, in the proposed method, the interchannel relationship among electroencephalogram (EEG data is utilized. It is expected that the correlation obtained from different combination of channels will be different for different mental tasks, which can be exploited to extract distinctive feature. The empirical mode decomposition (EMD technique is employed on a test EEG signal obtained from a channel, which provides a number of intrinsic mode functions (IMFs, and correlation coefficient is extracted from interchannel IMF data. Simultaneously, different statistical features are also obtained from each IMF. Finally, the feature matrix is formed utilizing interchannel correlation features and intrachannel statistical features of the selected IMFs of EEG signal. Different kernels of the support vector machine (SVM classifier are used to carry out the classification task. An EEG dataset containing ten different combinations of five different mental tasks is utilized to demonstrate the classification performance and a very high level of accuracy is achieved by the proposed scheme compared to existing methods.
Heart Rate Variability Correlates to Functional Aerobic Impairment in Hemodialysis Patients
Directory of Open Access Journals (Sweden)
Maria Angela Magalhães de Queiroz Carreira
2015-06-01
Full Text Available Background: Autonomic dysfunction (AD is highly prevalent in hemodialysis (HD patients and has been implicated in their increased risk of cardiovascular mortality. Objective: To correlate heart rate variability (HRV during exercise treadmill test (ETT with the values obtained when measuring functional aerobic impairment (FAI in HD patients and controls. Methods: Cross-sectional study involving HD patients and a control group. Clinical examination, blood sampling, transthoracic echocardiogram, 24-hour Holter, and ETT were performed. A symptom-limited ramp treadmill protocol with active recovery was employed. Heart rate variability was evaluated in time domain at exercise and recovery periods. Results: Forty-one HD patients and 41 controls concluded the study. HD patients had higher FAI and lower HRV than controls (p<0.001 for both. A correlation was found between exercise HRV (SDNN and FAI in both groups. This association was independent of age, sex, smoking, body mass index, diabetes, and clonidine or beta-blocker use, but not of hemoglobin levels. Conclusion: No association was found between FAI and HRV on 24-hour Holter or at the recovery period of ETT. Of note, exercise HRV was inversely correlated with FAI in HD patients and controls. (Arq Bras Cardiol. 2015; [online]. ahead print, PP.0-0
Digital Posturography Games Correlate with Gross Motor Function in Children with Cerebral Palsy.
Bingham, Peter M; Calhoun, Barbara
2015-04-01
This pilot study aimed to assess whether performance on posturography games correlates with the Gross Motor Function Measure (GMFM) in children with cerebral palsy. Simple games using static posturography technology allowed subjects to control screen events via postural sway. Game performance was compared with GMFMs using correlation analysis in a convenience sample of nine girls and six boys with cerebral palsy. Likert scales were used to obtain subjective responses to the balance games. GMFM scores correlated with game performance, especially measures emphasizing rhythmic sway. Twelve of the 15 subjects enjoyed the game and asserted an interest in playing again. Digital posturography games engage children with cerebral palsy in balance tasks, provide visual feedback in a balance control task, and have the potential to increase autonomy in balance control training among pediatric patients with cerebral palsy. This approach can support the relationship between child and therapist. The potential for interactive posturography to complement the assessment and treatment of balance in cerebral palsy bears continuing study.
Measurement of the dipole in the cross-correlation function of galaxies
Gaztanaga, Enrique; Hui, Lam
2017-01-01
It is usually assumed that in the linear regime the two-point correlation function of galaxies contains only a monopole, quadrupole and hexadecapole. Looking at cross-correlations between different populations of galaxies, this turns out not to be the case. In particular, the cross-correlations between a bright and a faint population of galaxies contain also a dipole. In this paper we present the first attempt to measure this dipole. We discuss the four types of effects that contribute to the dipole: relativistic distortions, evolution effect, wide-angle effect and large-angle effect. We show that the first three contributions are intrinsic anti-symmetric contributions that do not depend on the choice of angle used to measure the dipole. On the other hand the large-angle effect appears only if the angle chosen to extract the dipole breaks the symmetry of the problem. We show that the relativistic distortions, the evolution effect and the wide-angle effect are too small to be detected in the LOWz and CMASS sam...
Gillespie, Dirk; Khair, Aditya S; Bardhan, Jaydeep P; Pennathur, Sumita
2011-07-15
The electrokinetic behavior of nanofluidic devices is dominated by the electrical double layers at the device walls. Therefore, accurate, predictive models of double layers are essential for device design and optimization. In this paper, we demonstrate that density functional theory (DFT) of electrolytes is an accurate and computationally efficient method for computing finite ion size effects and the resulting ion-ion correlations that are neglected in classical double layer theories such as Poisson-Boltzmann. Because DFT is derived from liquid-theory thermodynamic principles, it is ideal for nanofluidic systems with small spatial dimensions, high surface charge densities, high ion concentrations, and/or large ions. Ion-ion correlations are expected to be important in these regimes, leading to nonlinear phenomena such as charge inversion, wherein more counterions adsorb at the wall than is necessary to neutralize its surface charge, leading to a second layer of co-ions. We show that DFT, unlike other theories that do not include ion-ion correlations, can predict charge inversion and other nonlinear phenomena that lead to qualitatively different current densities and ion velocities for both pressure-driven and electro-osmotic flows. We therefore propose that DFT can be a valuable modeling and design tool for nanofluidic devices as they become smaller and more highly charged. Copyright © 2011 Elsevier Inc. All rights reserved.
Shiklomanov, A. N.; Cowdery, E.; Dietze, M.
2016-12-01
Recent syntheses of global trait databases have revealed that although the functional diversity among plant species is immense, this diversity is constrained by trade-offs between plant strategies. However, the use of among-trait and trait-environment correlations at the global scale for both qualitative ecological inference and land surface modeling has several important caveats. An alternative approach is to preserve the existing PFT-based model structure while using statistical analyses to account for uncertainty and variability in model parameters. In this study, we used a hierarchical Bayesian model of foliar traits in the TRY database to test the following hypotheses: (1) Leveraging the covariance between foliar traits will significantly constrain our uncertainty in their distributions; and (2) Among-trait covariance patterns are significantly different among and within PFTs, reflecting differences in trade-offs associated with biome-level evolution, site-level community assembly, and individual-level ecophysiological acclimation. We found that among-trait covariance significantly constrained estimates of trait means, and the additional information provided by across-PFT covariance led to more constraint still, especially for traits and PFTs with low sample sizes. We also found that among-trait correlations were highly variable among PFTs, and were generally inconsistent with correlations within PFTs. The hierarchical multivariate framework developed in our study can readily be enhanced with additional levels of hierarchy to account for geographic, species, and individual-level variability.
Pair correlation function decay in models of simple fluids that contain dispersion interactions.
Evans, R; Henderson, J R
2009-11-25
We investigate the intermediate-and longest-range decay of the total pair correlation function h(r) in model fluids where the inter-particle potential decays as -r(-6), as is appropriate to real fluids in which dispersion forces govern the attraction between particles. It is well-known that such interactions give rise to a term in q(3) in the expansion of [Formula: see text], the Fourier transform of the direct correlation function. Here we show that the presence of the r(-6) tail changes significantly the analytic structure of [Formula: see text] from that found in models where the inter-particle potential is short ranged. In particular the pure imaginary pole at q = iα(0), which generates monotonic-exponential decay of rh(r) in the short-ranged case, is replaced by a complex (pseudo-exponential) pole at q = iα(0)+α(1) whose real part α(1) is negative and generally very small in magnitude. Near the critical point α(1)∼-α(0)(2) and we show how classical Ornstein-Zernike behaviour of the pair correlation function is recovered on approaching the mean-field critical point. Explicit calculations, based on the random phase approximation, enable us to demonstrate the accuracy of asymptotic formulae for h(r) in all regions of the phase diagram and to determine a pseudo-Fisher-Widom (pFW) line. On the high density side of this line, intermediate-range decay of rh(r) is exponentially damped-oscillatory and the ultimate long-range decay is power-law, proportional to r(-6), whereas on the low density side this damped-oscillatory decay is sub-dominant to both monotonic-exponential and power-law decay. Earlier analyses did not identify the pseudo-exponential pole and therefore the existence of the pFW line. Our results enable us to write down the generic wetting potential for a 'real' fluid exhibiting both short-ranged and dispersion interactions. The monotonic-exponential decay of correlations associated with the pseudo-exponential pole introduces additional terms into
International Nuclear Information System (INIS)
Goodpaster, Jason D.; Barnes, Taylor A.; Miller, Thomas F.; Manby, Frederick R.
2014-01-01
We analyze the sources of error in quantum embedding calculations in which an active subsystem is treated using wavefunction methods, and the remainder using density functional theory. We show that the embedding potential felt by the electrons in the active subsystem makes only a small contribution to the error of the method, whereas the error in the nonadditive exchange-correlation energy dominates. We test an MP2 correction for this term and demonstrate that the corrected embedding scheme accurately reproduces wavefunction calculations for a series of chemical reactions. Our projector-based embedding method uses localized occupied orbitals to partition the system; as with other local correlation methods, abrupt changes in the character of the localized orbitals along a reaction coordinate can lead to discontinuities in the embedded energy, but we show that these discontinuities are small and can be systematically reduced by increasing the size of the active region. Convergence of reaction energies with respect to the size of the active subsystem is shown to be rapid for all cases where the density functional treatment is able to capture the polarization of the environment, even in conjugated systems, and even when the partition cuts across a double bond
International Nuclear Information System (INIS)
Demirkazik, Figen Basaran; Ariyuerek, O. Macit; Oezcelik, Ugur; Goecmen, Ayhan; Hassanabad, Hossein K.; Kiper, Nural
2001-01-01
Objective: To compare the high resolution CT (HRCT) scores of the Bhalla system with pulmonary function tests and radiographic and clinical points of the Shwachman-Kulczycki clinical scoring system. Methods: HRCT of the chest was obtained in 40 children to assess the role of HRCT in evaluating bronchopulmonary pathology in children with cystic fibrosis (CF). The HRCT severity scores of the Bhalla system were compared with chest radiographic and clinical points of the Shwachman-Kulczycki scoring system and pulmonary function tests. Only 14 of the patients older than 6 years cooperated with spirometry. Results: HRCT scores correlated well with radiographic points (r=0.80, P 1 (r=0.66, P=0.01). Although radiographic points correlated significantly with FVC (r=0.61, P=0.02) and FEV 1 (r=0.56, P=0.04), HRCT provides a more precise scoring than the chest X-ray. Conclusion: The HRCT scoring system may provide a sensitive method of monitoring pulmonary disease status and may replace the radiographic scoring in the Shwachman-Kulczycki system. It may be helpful especially in follow-up of small children too young to cooperate with spirometry
Correlation of color doppler image and thyroid function test in diffuse goiter
International Nuclear Information System (INIS)
Kim, Kyung Rak; Hong, Hyun Sook; Seo, Kwang Won; Jung, Mi Sun; Lee, Hae Kyung; Kwon, Kui Hyang; Choi, Deuk Lin; Yoo, Myung Hee
1997-01-01
To determine whether CDI can differentiate Graves' disease from other cases of thyroiditis and to determine the relationship between CDI findings and TFT. Between October, 1995 and January, 1996, 22 cases of diffuse goiter without nodule were prospectively assessed for CDI and TFT. CDI was classified into three groups:Grade 1 (minimal), Grade 2 (moderate), and Grade 3 (marked);TFT was also classified into three groups:decreased, normal, and increased thyroid function. The correlation between CDI and TFT was statistically assessed;each case was diagnosed by aspiration biopsy or clinical laboratory studies. All Graves' disease patients showed good correlation between marked color flows and increased thyroid function. The CDI findings of other cases of thyroiditis showed variable color flow and TFT. We found significant differences between the two disease groups. CDI can help differentiate Graves' disease from other cases of thyroiditis and additional assesment using TFT will help in the diagnosis of diffuse goiter. The 'thyroid inferno' pattern in not a specific finding of Graves' disease
Measurement system of correlation functions of microwave single photon source in real time
Korenkov, A.; Dmitriev, A.; Astafiev, O.
2018-02-01
Several quantum setups, such as quantum key distribution networks[1] and quantum simulators (e.g. boson sampling), by their design rely on single photon sources (SPSs). These quantum setups were demonstrated to operate in optical frequency domain. However, following the steady advances in circuit quantum electrodynamics, a proposal has been made recently[2] to demonstrate boson sampling with microwave photons. This in turn requires the development of reliable microwave SPS. It's one of the most important characteristics are the first-order and the second-order correlation functions g1 and g2. The measurement technique of g1 and g2 is significantly different from that in the optical domain [3],[4] because of the current unavailability of microwave single-photon detectors. In particular, due to high levels of noise present in the system a substantial amount of statistics in needed to be acquired. This work presents a platform for measurement of g1 and g2 that processes the incoming data in real time, maximizing the efficiency of data acquisition. The use of field-programmable gate array (FPGA) electronics, common in similar experiments[3] but complex in programming, is avoided; instead, the calculations are performed on a standard desktop computer. The platform is used to perform the measurements of the first-order and the second-order correlation functions of the microwave SPS.
T\\overline{T} -deformations, AdS/CFT and correlation functions
Giribet, Gaston
2018-02-01
A solvable irrelevant deformation of AdS3/CFT2 correspondence leading to a theory with Hagedorn spectrum at high energy has been recently proposed. It consists of a single trace deformation of the boundary theory, which is inspired by the recent work on solvable T\\overline{T} deformations of two-dimensional CFTs. Thought of as a worldsheet σ-model, the interpretation of the deformed theory from the bulk viewpoint is that of string theory on a background that interpolates between AdS3 in the IR and a linear dilaton vacuum of little string theory in the UV. The insertion of the operator that realizes the deformation in the correlation functions produces a logarithmic divergence, leading to the renormalization of the primary operators, which thus acquire an anomalous dimension. We compute this anomalous dimension explicitly, and this provides us with a direct way of determining the spectrum of the theory. We discuss this and other features of the correlation functions in presence of the deformation.
Energy Technology Data Exchange (ETDEWEB)
Demirkazik, Figen Basaran E-mail: demirkaz@dialup.ankara.edu.tr; Ariyuerek, O. Macit; Oezcelik, Ugur; Goecmen, Ayhan; Hassanabad, Hossein K.; Kiper, Nural
2001-01-01
Objective: To compare the high resolution CT (HRCT) scores of the Bhalla system with pulmonary function tests and radiographic and clinical points of the Shwachman-Kulczycki clinical scoring system. Methods: HRCT of the chest was obtained in 40 children to assess the role of HRCT in evaluating bronchopulmonary pathology in children with cystic fibrosis (CF). The HRCT severity scores of the Bhalla system were compared with chest radiographic and clinical points of the Shwachman-Kulczycki scoring system and pulmonary function tests. Only 14 of the patients older than 6 years cooperated with spirometry. Results: HRCT scores correlated well with radiographic points (r=0.80, P<0.0001) and clinical points (r=0.67, P<0.0001) of the Shwachman-Kulczycki system, FVC (r=0.71 P=0.004) and FEV{sub 1} (r=0.66, P=0.01). Although radiographic points correlated significantly with FVC (r=0.61, P=0.02) and FEV{sub 1} (r=0.56, P=0.04), HRCT provides a more precise scoring than the chest X-ray. Conclusion: The HRCT scoring system may provide a sensitive method of monitoring pulmonary disease status and may replace the radiographic scoring in the Shwachman-Kulczycki system. It may be helpful especially in follow-up of small children too young to cooperate with spirometry.
International Nuclear Information System (INIS)
Sun, Jianwei; Yang, Zenghui; Peng, Haowei; Perdew, John P.
2016-01-01
The uniform electron gas and the hydrogen atom play fundamental roles in condensed matter physics and quantum chemistry. The former has an infinite number of electrons uniformly distributed over the neutralizing positively charged background, and the latter only one electron bound to the proton. The uniform electron gas was used to derive the local spin density approximation to the exchange-correlation functional that undergirds the development of the Kohn-Sham density functional theory. We show here that the ground-state exchange-correlation energies of the hydrogen atom and many other 1- and 2-electron systems are modeled surprisingly well by a different local spin density approximation (LSDA0). LSDA0 is constructed to satisfy exact constraints but agrees surprisingly well with the exact results for a uniform two-electron density in a finite, curved three-dimensional space. We also apply LSDA0 to excited or noded 1-electron densities, where it works less well. Furthermore, we show that the localization of the exact exchange hole for a 1- or 2-electron ground state can be measured by the ratio of the exact exchange energy to its optimal lower bound.
On the Decay Ratio Determination in BWR Stability Analysis by Auto-Correlation Function Techniques
International Nuclear Information System (INIS)
Behringer, K.; Hennig, D.
2002-11-01
A novel auto-correlation function (ACF) method has been investigated for determining the oscillation frequency and the decay ratio in BWR stability analyses. The neutron signals are band-pass filtered to separate the oscillation peak in the power spectral density (PSD) from background. Two linear second-order oscillation models are considered. These models, corrected for signal filtering and including a background term under the peak in the PSD, are then least-squares fitted to the ACF of the previously filtered neutron signal, in order to determine the oscillation frequency and the decay ratio. Our method uses fast Fourier transform techniques with signal segmentation for filtering and ACF estimation. Gliding 'short-term' ACF estimates on a record allow the evaluation of uncertainties. Numerical results are given which have been obtained from neutron data of the recent Forsmark I and Forsmark II NEA benchmark project. Our results are compared with those obtained by other participants in the benchmark project. The present PSI report is an extended version of the publication K. Behringer, D. Hennig 'A novel auto-correlation function method for the determination of the decay ratio in BWR stability studies' (Behringer, Hennig, 2002)
On exact correlation functions in SU(N) $ \\mathcal{N}=2 $ superconformal QCD
Baggio, Marco; Papadodimas, Kyriakos
2015-01-01
We consider the exact coupling constant dependence of extremal correlation functions of ${\\cal N} = 2$ chiral primary operators in 4d ${\\cal N} = 2$ superconformal gauge theories with gauge group SU(N) and N_f=2N massless fundamental hypermultiplets. The 2- and 3-point functions, viewed as functions of the exactly marginal coupling constant and theta angle, obey the tt* equations. In the case at hand, the tt* equations form a set of complicated non-linear coupled matrix equations. We point out that there is an ad hoc self-consistent ansatz that reduces this set of partial differential equations to a sequence of decoupled semi-infinite Toda chains, similar to the one encountered previously in the special case of SU(2) gauge group. This ansatz requires a surprising new non-renormalization theorem in ${\\cal N} = 2$ superconformal field theories. We derive a general 3-loop perturbative formula for 2- and 3-point functions in the ${\\cal N} = 2$ chiral ring of the SU(N) theory, and in all explicitly computed exampl...
Tanaka, Fumio; Tominaga, Kazunari; Fujikawa, Yoshiko; Nagami, Yasuaki; Kamata, Noriko; Yamagami, Hirokazu; Tanigawa, Tetsuya; Shiba, Masatsugu; Watanabe, Toshio; Fujiwara, Yasuhiro; Arakawa, Tetsuo
2016-12-01
In patients with functional dyspepsia (FD), mild duodenal inflammation correlates with increased mucosal permeability. Enteric glial cells can produce glial cell line-derived neurotrophic factor (GDNF) to repair disrupted epithelial barrier function. We examined the role of duodenal GDNF in FD pathophysiology and its association with dyspeptic symptoms. Duodenal biopsies taken from FD patients and control subjects were used for analysis. GDNF protein expression and localization were examined. Cellular infiltration of eosinophils and mast cells was measured. We also examined the intercellular space between the adjacent epithelial cells at the apical junction complex using transmission electron microscopy. In FD patients, expression of GDNF protein was significantly increased compared with controls, 107.3 (95.3-136.7) versus 49.3 (38.0-72.6) pg/mg protein (median (interquartile range), p = 0.006), respectively. GDNF was localized in enteric glial cells, eosinophils, and epithelial cells. The number of eosinophils was significantly greater in FD patients than in controls, 1039 (923-1181) versus 553 (479-598) cells/mm 2 (p = 0.021), respectively. The intercellular space was dilated at the adherent junction in FD patients compared to control patients, 32.4 (29.8-34.8) versus 22.0 (19.9-26.1) nm (p = 0.002), respectively. Intercellular distance positively correlated with the frequency of postprandial fullness and early satiation (p = 0.001, r = 0.837 and p = 0.009, r = 0.693, respectively). Expression of GDNF correlated with epigastric burning (p = 0.041, r = 0.552). Increased expression of duodenal GDNF might be involved in FD pathophysiology and symptom perception.
Women with low libido: correlation of decreased androgen levels with female sexual function index.
Turna, B; Apaydin, E; Semerci, B; Altay, B; Cikili, N; Nazli, O
2005-01-01
The aim of the present study was to investigate a possible correlation between decreased androgen levels and female sexual function index (FSFI) in women with low libido and compare these findings with normal age-matched subjects. In total, 20 premenopausal women with low libido (mean age 36.7; range 24-51 y) and 20 postmenopausal women with low libido (mean age 54; 45-70 y), and 20 premenopausal healthy women (mean age 32.2; range 21-51 y) and 20 postmenopausal healthy women (mean age 53.5; range 48-60 y) as controls were enrolled in the current study. Women with low libido had symptoms for at least 6 months and were in stable relationships. All premenopausal patients had regular menstrual cycles and all postmenopausal patients and controls were on estrogen replacement therapy. None of the patients were taking birth control pills, corticosteroids or had a history of chronic medical illnesses. All completed the FSFI and Beck's Depression Inventory (BDI) questionnaires. Hormones measured included: cortisol; T3, T4 and TSH; estradiol; total and free testosterone; dehydroepiandrosterone sulfate (DHEA-S); sex hormone binding globulin (SHBG). We performed statistical analysis by parametric and nonparametric comparisons and correlations, as appropriate. We found significant differences between the women with low libido and the controls in total testosterone, free testosterone and DHEA-S levels and full-scale FSFI score for both pre- and postmenopausal women (Plibido have lower androgen levels compared to age-matched normal control groups and their decreased androgen levels correlate positively with female sexual function index domains.
Poretti, Andrea; Snow, Joseph; Summers, Angela C; Tekes, Aylin; Huisman, Thierry A G M; Aygun, Nafi; Carson, Kathryn A; Doherty, Dan; Parisi, Melissa A; Toro, Camilo; Yildirimli, Deniz; Vemulapalli, Meghana; Mullikin, Jim C; Cullinane, Andrew R; Vilboux, Thierry; Gahl, William A; Gunay-Aygun, Meral
2017-08-01
Joubert syndrome is a clinically and genetically heterogeneous ciliopathy. Neuroimaging findings have not been systematically evaluated in a large cohort of patients with Joubert syndrome in correlation with molecular genetic cause and cognitive function. Brain MRI of 110 patients with Joubert syndrome was included in this study. A comprehensive evaluation of brain MRI studies for infratentorial and supratentorial morphological abnormalities was performed. Genetic cause was identified by whole-exome sequencing, and cognitive functions were assessed with age-appropriate neurocognitive tests in a subset of patients. The cerebellar hemispheres were enlarged in 18% of the patients, mimicking macrocerebellum. The posterior fossa was enlarged in 42% of the patients, resembling Dandy-Walker malformation. Abnormalities of the brainstem, such as protuberance at the ventral contour of the midbrain, were present in 66% of the patients. Abnormalities of the supratentorial brain were present in approximately one-third of the patients, most commonly malrotation of the hippocampi. Mild ventriculomegaly, which typically did not require shunting, was present in 23% of the patients. No correlation between neuroimaging findings and molecular genetic cause was apparent. A novel predictor of outcome was identified; the more severe the degree of vermis hypoplasia, the worse the neurodevelopmental outcome was. The spectrum of neuroimaging findings in Joubert syndrome is wide. Neuroimaging does not predict the genetic cause, but may predict the neurodevelopmental outcome. A high degree of vermis hypoplasia correlates with worse neurodevelopmental outcome. This finding is important for prognostic counselling in Joubert syndrome. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Thin-section CT imaging that correlates with pulmonary function tests in obstructive airway disease
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Arakawa, Hiroaki, E-mail: arakawa@dokkyomed.ac.jp [Department of Radiology, Dokkyo Medical University, 880 Kita-Kobayashi, Mibu, Tochigi 321-0293 (Japan); Fujimoto, Kiminori [Department of Radiology, Kurume University School of Medicine (Japan); Fukushima, Yasutugu [Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University (Japan); Kaji, Yasushi [Department of Radiology, Dokkyo Medical University, 880 Kita-Kobayashi, Mibu, Tochigi 321-0293 (Japan)
2011-11-15
Purpose: The purpose of this study was to identify independent CT findings that correlated with pulmonary function tests (PFTs) in patients with obstructive airway diseases. Materials and methods: Sixty-eight patients with obstructive airway disease and 29 normal subjects (mean age, 52 years; 36 men and 61 women) underwent inspiratory and expiratory thin-section CT and PFTs. Patient with obvious emphysema was excluded. Two radiologists independently reviewed the images and semi-quantitatively evaluated lung attenuation (mosaic perfusion, air trapping) and airway abnormalities (extent and severity of bronchial wall thickening and bronchiectasis, bronchiolectasis or centrilobular nodules, mucous plugging). Univariate, multivariate and receiver operating characteristic (ROC) analyses were performed with CT findings and PFTs. Results: Forty-two patients showed obstructive PFTs, 26 symptomatic patients showed near-normal PFTs. On univariate analysis, air trapping and bronchial wall thickening showed highest correlation with obstructive PFTs such as FEV1.0/FVC, MMEF and FEF75 (r ranged from -0.712 to -0.782; p < 0.001), while mosaic perfusion and mucous plugging showed moderate correlation, and bronchiectasis, bronchiolectasis and nodules showed the least, but significant, correlation. Multiple logistic analyses revealed air trapping and bronchial wall thickening as the only significant independent determinants of obstructive PFTs. ROC analysis revealed the cut-off value of air trapping for obstructive PFTs to be one-third of whole lung (area under curve, 0.847). Conclusions: Our study confirmed air trapping and bronchial wall thickening are the most important observations when imaging obstructive PFTs. The cut-off value of air trapping for identifying obstructive PFTs was one-third of lung irrespective of inspiratory CT findings.
International Nuclear Information System (INIS)
Johnson, E.
1977-01-01
A theory for site-site pair distribution functions of molecular fluids is derived from the Ornstein-Zernike equation. Atom-atom pair distribution functions of this theory which were obtained by using different approximations for the Percus-Yevick site-site direct correlation functions are compared
Directory of Open Access Journals (Sweden)
WenJun Zhang
2017-09-01
Full Text Available In present study I used the data from CHM-DATA, the interactive database of 1127 Chinese herbal medicines. Canonical correlation functions were determined for taste attribute class (7 taste attributes, medicinal property class (5 medicinal properties, chemical composition class (22 chemical composition categories, meridians and colleterals class (12 meridians and colleterals, and medicinal function class (77 medicinal functions. Linear eignmodels were also developed for Chinese herbal medicines. Theoretically the attribute values of any Chinese herbal medicines meet the corresponding linear eignmodel. Matlab codes for canonical correlation analysis and linear eignmodel were given. Finally, the canonical correlation network for attribute classes of Chinese herbal medicines was constructed.
Directory of Open Access Journals (Sweden)
Mai Banakhar
2015-06-01
Full Text Available Sacral neuromodulation (SNM has become an established therapy for voiding dysfunction (VD. There have been published papers that documented improvement in bowel functions and bladder pain via SNM. However, improvement in female sexual function (FSF after SNM treatment remains unclear. Recently, Banakhar et al. evaluated the effects of SNM on FSF and its impact on quality of life (QoL and analyzed any correlation. They evaluated 33 female patients who were treated with SNM for VD. All patients completed the Female Sexual Function Index (FSFI, the 36-Item Short-Form Health Survey (SF-36, and incontinence questionnaires (the Urinary Distress Inventory [UDI-6] preoperatively and 4 months postoperatively. Ten patients were excluded from the study because they were not sexually active. The indications were: refractory overactive bladder in 19, frequency urgency syndrome in 2, and non-obstructive urinary retention in another 2 patients. SNM therapy significantly improved the total FSFI score (p=0.011. When the SF-36 and UDI-6 scores were compared, QoL showed significant improvement after SNM treatment. However, improvement in FSFI scores was not correlated with improvement in QoL. SNM therapy is an effective treatment modality in selected patient groups. In our country, SNM therapy has become a new option in the treatment of lower urinary tract problems. According to the results of this study, it is too early to conclude that SNM certainly improve FSF and QoL. The study just evaluated 23 cases. In order to have a more discrete conclusion, we need prospective trials with larger series
Wang, Yida; Cohen, Jonathan D; Li, Kai; Turk-Browne, Nicholas B
2015-08-15
The analysis of brain imaging data often requires simplifying assumptions because exhaustive analyses are computationally intractable. Standard univariate and multivariate analyses of brain activity ignore interactions between regions and analyses of interactions (functional connectivity) reduce the computational challenge by using seed regions of interest or brain parcellations. To meet this challenge, we developed full correlation matrix analysis (FCMA), which leverages and optimizes algorithms from parallel computing and machine learning to efficiently analyze the pairwise correlations of all voxels in the brain during different cognitive tasks, with the goal of identifying task-related interactions in an unbiased manner. When applied to a localizer dataset on a small compute cluster, FCMA accelerated a naive, serial approach by four orders of magnitude, reducing running time from two years to one hour. In addition to this performance gain, FCMA emphasized different brain areas than existing methods. In particular, beyond replicating known category selectivity in visual cortex, FCMA also revealed a region of medial prefrontal cortex whose selectivity derived from differential patterns of functional connectivity across categories. For benchmarking, we started with a naive approach and progressively built up to the complete FCMA procedure by adding optimized classifier algorithms, multi-threaded parallelism, and multi-node parallelism. To evaluate what can be learned with FCMA, we compared it against multivariate pattern analysis of activity and seed-based analysis of functional connectivity. FCMA demonstrates how advances in computer science can alleviate computational bottlenecks in neuroscience. We have released a software toolbox to help others evaluate FCMA. Copyright © 2015 Elsevier B.V. All rights reserved.
Tonacci, Alessandro; Bruno, Rosa M; Ghiadoni, Lorenzo; Pratali, Lorenza; Berardi, Nicoletta; Tognoni, Gloria; Cintoli, Simona; Volpi, Leda; Bonuccelli, Ubaldo; Sicari, Rosa; Taddei, Stefano; Maffei, Lamberto; Picano, Eugenio
2017-05-01
Mild Cognitive Impairment (MCI) is an intermediate condition between normal aging and dementia, associated with an increased risk of progression into the latter within months or years. Olfactory impairment, a well-known biomarker for neurodegeneration, might be present in the condition early, possibly representing a signal for future pathological onset. Our study aimed at evaluating olfactory function in MCI and healthy controls in relation to neurocognitive performance and endothelial function. A total of 85 individuals with MCI and 41 healthy controls, matched for age and gender, were recruited. Olfactory function was assessed by Sniffin' Sticks Extended Test (Burghart, Medizintechnik, GmbH, Wedel, Germany). A comprehensive neurocognitive assessment was performed. Endothelial function was assessed by flow-mediated dilation (FMD) of the brachial artery by ultrasound. MCI individuals showed an impaired olfactory function compared to controls. The overall olfactory score is able to predict MCI with a good sensitivity and specificity (70.3 and 77.4% respectively). In MCI, olfactory identification score is correlated with a number of neurocognitive abilities, including overall cognitive status, dementia rating, immediate and delayed memory, visuospatial ability and verbal fluency. FMD was reduced in MCI (2.90 ± 2.15 vs. 3.66 ± 1.96%, P = 0.016) and was positively associated with olfactory identification score (ρ s =0.219, P = 0.025). The association remained significant after controlling for age, gender, and smoking. In conclusion, olfactory evaluation is able to discriminate between MCI and healthy individuals. Systemic vascular dysfunction might be involved, at least indirectly, in olfactory dysfunction in MCI. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.
Williams, Amy M; Lindholm, Jamie; Siddiqui, Farzan; Ghanem, Tamer A; Chang, Steven S
2017-11-01
Objective Identify the prevalence and clinical correlates of cognitive impairment in patients presenting for treatment of head and neck cancer (HNC) using brief screening within a multidisciplinary care team. Study Design A case series with planned data collection of cognitive function, quality of life (QoL), and psychosocial variables. Setting Urban Midwest academic medical center. Subjects and Methods In total, 209 consecutive patients with a diagnosis of HNC between August 2015 and September 2016 who had a pretreatment assessment with a clinical health psychologist. At pretreatment assessment, the Montreal Cognitive Assessment (MoCA), a brief screening tool for cognitive function, was administered along with a semistructured interview to gather information on psychiatric symptoms, social support, and substance use. Patient information, including demographics, clinical variables, and psychosocial variables, was extracted via chart review. A subset of patients with HNC completed the Functional Assessment of Cancer Therapy-Head and Neck Cancer at pretreatment assessment and was included in the QoL analyses. Results Cognitive impairment was associated with current alcohol use, past tobacco use and number of pack years, time in radiotherapy, and adherence to treatment recommendations. Social, emotional, and functional QoL scales were associated with cognitive impairment, including executive function, language, and memory. Conclusion Cognitive impairment is common in patients with HNC, and there are important associations between cognitive impairment and psychosocial, QoL, and treatment adherence variables. The results argue for the incorporation of cognitive screening as part of pretreatment assessment for patients, as well as further research into more direct, causal relationships via longitudinal, prospective studies.
Ranft, Andreas; Golkowski, Daniel; Kiel, Tobias; Riedl, Valentin; Kohl, Philipp; Rohrer, Guido; Pientka, Joachim; Berger, Sebastian; Thul, Alexander; Maurer, Max; Preibisch, Christine; Zimmer, Claus; Mashour, George A; Kochs, Eberhard F; Jordan, Denis; Ilg, Rüdiger
2016-11-01
The neural correlates of anesthetic-induced unconsciousness have yet to be fully elucidated. Sedative and anesthetic states induced by propofol have been studied extensively, consistently revealing a decrease of frontoparietal and thalamocortical connectivity. There is, however, less understanding of the effects of halogenated ethers on functional brain networks. The authors recorded simultaneous resting-state functional magnetic resonance imaging and electroencephalography in 16 artificially ventilated volunteers during sevoflurane anesthesia at burst suppression and 3 and 2 vol% steady-state concentrations for 700 s each to assess functional connectivity changes compared to wakefulness. Electroencephalographic data were analyzed using symbolic transfer entropy (surrogate of information transfer) and permutation entropy (surrogate of cortical information processing). Functional magnetic resonance imaging data were analyzed by an independent component analysis and a region-of-interest-based analysis. Electroencephalographic analysis showed a significant reduction of anterior-to-posterior symbolic transfer entropy and global permutation entropy. At 2 vol% sevoflurane concentrations, frontal and thalamic networks identified by independent component analysis showed significantly reduced within-network connectivity. Primary sensory networks did not show a significant change. At burst suppression, all cortical networks showed significantly reduced functional connectivity. Region-of-interest-based thalamic connectivity at 2 vol% was significantly reduced to frontoparietal and posterior cingulate cortices but not to sensory areas. Sevoflurane decreased frontal and thalamocortical connectivity. The changes in blood oxygenation level dependent connectivity were consistent with reduced anterior-to-posterior directed connectivity and reduced cortical information processing. These data advance the understanding of sevoflurane-induced unconsciousness and contribute to a
Directory of Open Access Journals (Sweden)
da Silva SMD
2016-03-01
Full Text Available Silvia Maria Doria da Silva, Ilma Aparecida Paschoal, Eduardo Mello De Capitani, Marcos Mello Moreira, Luciana Campanatti Palhares, Mônica Corso PereiraPneumology Service, Department of Internal Medicine, School of Medical Sciences, State University of Campinas (UNICAMP, Campinas, São Paulo, BrazilBackground: Computed tomography (CT phenotypic characterization helps in understanding the clinical diversity of chronic obstructive pulmonary disease (COPD patients, but its clinical relevance and its relationship with functional features are not clarified. Volumetric capnography (VC uses the principle of gas washout and analyzes the pattern of CO2 elimination as a function of expired volume. The main variables analyzed were end-tidal concentration of carbon dioxide (ETCO2, Slope of phase 2 (Slp2, and Slope of phase 3 (Slp3 of capnogram, the curve which represents the total amount of CO2 eliminated by the lungs during each breath.Objective: To investigate, in a group of patients with severe COPD, if the phenotypic analysis by CT could identify different subsets of patients, and if there was an association of CT findings and functional variables.Subjects and methods: Sixty-five patients with COPD Gold III–IV were admitted for clinical evaluation, high-resolution CT, and functional evaluation (spirometry, 6-minute walk test [6MWT], and VC. The presence and profusion of tomography findings were evaluated, and later, the patients were identified as having emphysema (EMP or airway disease (AWD phenotype. EMP and AWD groups were compared; tomography findings scores were evaluated versus spirometric, 6MWT, and VC variables.Results: Bronchiectasis was found in 33.8% and peribronchial thickening in 69.2% of the 65 patients. Structural findings of airways had no significant correlation with spirometric variables. Air trapping and EMP were strongly correlated with VC variables, but in opposite directions. There was some overlap between the EMP and AWD
Di Lieto, Maria Chiara; Brovedani, Paola; Pecini, Chiara; Chilosi, Anna Maria; Belmonti, Vittorio; Fabbro, Franco; Urgesi, Cosimo; Fiori, Simona; Guzzetta, Andrea; Perazza, Silvia; Sicola, Elisa; Cioni, Giovanni
2017-02-01
The neuropsychological literature on preterm-born children with spastic diplegia due to periventricular leukomalacia is convergent in reporting deficits in non-verbal intelligence and in visuo-spatial abilities. Nevertheless, other cognitive functions have found to be impaired, but data are scant and not correlated with neuroimaging findings. This study analyzes the neuropsychological strengths and weaknesses in preterm-born children with spastic diplegia (pSD) and their relationships with neuroanatomical findings, investigated by a novel scale for MRI classification. Nineteen children with pSD, mild to moderate upper limb impairment and Verbal IQ>80, and 38 normal controls were evaluated with a comprehensive neuropsychological battery (NEPSY-II), assessing Attention/Executive Functioning, Language, Memory, Sensorimotor, Social Perception and Visuospatial Processing domains. The MRIs were quantitatively scored for lesion severity. The results showed that, beyond core visuo-spatial and sensory-motor deficits, impairments in attention and executive functions were present in more than half of the sample, particularly in children with damage to the anterior corpus callosum. The findings are discussed in terms of clinical and rehabilitative implications tailored for pSD subgroups diversified for neuropsychological and neuroanatomical characteristics. Copyright © 2016 Elsevier Ltd. All rights reserved.
Correlation of Theory and Function in Well-Defined Bimetallic Electrocatalysts - Final Report
Energy Technology Data Exchange (ETDEWEB)
Crooks, Richard M.
2014-06-05
The objective of this research proposal was to correlate the structure of nanoparticles that are comprised of ~100-200 atoms to their electrocatalytic function. This objective was based on the growing body of evidence suggesting that catalytic properties can be tailored through controlled synthesis of nanoparticles. What has been missing from many of these studies, and what we are contributing, is a model catalyst that is sufficiently small, structurally well-defined, and well-characterized that its function can be directly predicted by theory. Specifically, our work seeks to develop a fundamental and detailed understanding of the relationship between the structure of nanoscopic oxygen-reduction catalysts and their function. We assembled a team with expertise in theory, synthesis, and advanced characterization methods to address the primary objective of this project. We anticipated the outcomes of the study to be: (1) a better theoretical understanding of how nanoparticle structure affects catalytic properties; (2) the development of advanced, in-situ and ex-situ, atomic-scale characterization methods that are appropriate for particles containing about 100 atoms; and (3) improved synthetic methods that produce unique nanoparticle structures that can be used to test theoretical predictions. During the project period, we have made excellent progress on all three fronts.
International Nuclear Information System (INIS)
Backes, Steffen
2017-04-01
The study of the electronic properties of correlated systems is a very diverse field and has lead to valuable insight into the physics of real materials. In these systems, the decisive factor that governs the physical properties is the ratio between the electronic kinetic energy, which promotes delocalization over the lattice, and the Coulomb interaction, which instead favours localized electronic states. Due to this competition, correlated electronic systems can show unique and interesting properties like the Metal-Insulator transition, diverse phase diagrams, strong temperature dependence and in general a high sensitivity to the environmental conditions. A theoretical description of these systems is not an easy task, since perturbative approaches that do not preserve the competition between the kinetic and interaction terms can only be applied in special limiting cases. One of the most famous approaches to obtain the electronic properties of a real material is the ab initio density functional theory (DFT) method. It allows one to obtain the ground state density of the system under investigation by mapping onto an effective non-interacting system that has to be found self-consistently. While being an exact theory, in practical implementations certain approximations have to be made to the exchange-correlation potential. The local density approximation (LDA), which approximates the exchange-correlation contribution to the total energy by that of a homogeneous electron gas with the corresponding density, has proven quite successful in many cases. Though, this approximation in general leads to an underestimation of electronic correlations and is not able to describe a metal-insulator transition due to electronic localization in the presence of strong Coulomb interaction. A different approach to the interacting electronic problem is the dynamical mean-field theory (DMFT), which is non-perturbative in the kinetic and interaction term but neglects all non
Energy Technology Data Exchange (ETDEWEB)
Backes, Steffen
2017-04-15
The study of the electronic properties of correlated systems is a very diverse field and has lead to valuable insight into the physics of real materials. In these systems, the decisive factor that governs the physical properties is the ratio between the electronic kinetic energy, which promotes delocalization over the lattice, and the Coulomb interaction, which instead favours localized electronic states. Due to this competition, correlated electronic systems can show unique and interesting properties like the Metal-Insulator transition, diverse phase diagrams, strong temperature dependence and in general a high sensitivity to the environmental conditions. A theoretical description of these systems is not an easy task, since perturbative approaches that do not preserve the competition between the kinetic and interaction terms can only be applied in special limiting cases. One of the most famous approaches to obtain the electronic properties of a real material is the ab initio density functional theory (DFT) method. It allows one to obtain the ground state density of the system under investigation by mapping onto an effective non-interacting system that has to be found self-consistently. While being an exact theory, in practical implementations certain approximations have to be made to the exchange-correlation potential. The local density approximation (LDA), which approximates the exchange-correlation contribution to the total energy by that of a homogeneous electron gas with the corresponding density, has proven quite successful in many cases. Though, this approximation in general leads to an underestimation of electronic correlations and is not able to describe a metal-insulator transition due to electronic localization in the presence of strong Coulomb interaction. A different approach to the interacting electronic problem is the dynamical mean-field theory (DMFT), which is non-perturbative in the kinetic and interaction term but neglects all non
Neural correlates of the popular music phenomenon: evidence from functional MRI and PET imaging
International Nuclear Information System (INIS)
Chen, Qiaozhen; Zhang, Ying; Hou, Haifeng; Du, Fenglei; Wu, Shuang; Chen, Lin; Shen, Yehua; Chao, Fangfang; Zhang, Hong; Tian, Mei; Chung, June-key
2017-01-01
Music can induce different emotions. However, its neural mechanism remains unknown. The aim of this study was to use functional magnetic resonance imaging (fMRI) and position emission tomography (PET) imaging for mapping of neural changes under the most popular music in healthy volunteers. Blood-oxygen-level-dependent (BOLD) fMRI and monoamine receptor PET imaging with 11 C-N-methylspiperone ( 11 C-NMSP) were conducted under the popular music Gangnam Style and light music A Comme Amour in healthy subjects. PET and fMRI images were analyzed by using the Statistical Parametric Mapping software (SPM). Significantly increased fMRI BOLD signals were found in the bilateral superior temporal cortices, left cerebellum, left putamen and right thalamus cortex. Monoamine receptor availability was increased significantly in the left superior temporal gyrus and left putamen, but decreased in the bilateral superior occipital cortices under the Gangnam Style compared with the light music condition. Significant positive correlation was found between 11 C-NMSP binding and fMRI BOLD signals in the left temporal cortex. Furthermore, increased 11 C-NMSP binding in the left putamen was positively correlated with the mood arousal level score under the Gangnam Style condition. Popular music Gangnam Style can arouse pleasure experience and strong emotional response. The left putamen is positively correlated with the mood arousal level score under the Gangnam Style condition. Our results revealed characteristic patterns of brain activity associated with Gangnam Style, and may also provide more general insights into the music-induced emotional processing. (orig.)
Low-energy effective Hamiltonians for correlated electron systems beyond density functional theory
Hirayama, Motoaki; Miyake, Takashi; Imada, Masatoshi; Biermann, Silke
2017-08-01
We propose a refined scheme of deriving an effective low-energy Hamiltonian for materials with strong electronic Coulomb correlations beyond density functional theory (DFT). By tracing out the electronic states away from the target degrees of freedom in a controlled way by a perturbative scheme, we construct an effective Hamiltonian for a restricted low-energy target space incorporating the effects of high-energy degrees of freedom in an effective manner. The resulting effective Hamiltonian can afterwards be solved by accurate many-body solvers. We improve this "multiscale ab initio scheme for correlated electrons" (MACE) primarily in two directions by elaborating and combining two frameworks developed by Hirayama et al. [M. Hirayama, T. Miyake, and M. Imada, Phys. Rev. B 87, 195144 (2013), 10.1103/PhysRevB.87.195144] and Casula et al. [M. Casula, P. Werner, L. Vaugier, F. Aryasetiawan, T. Miyake, A. J. Millis, and S. Biermann, Phys. Rev. Lett. 109, 126408 (2012), 10.1103/PhysRevLett.109.126408]: (1) Double counting of electronic correlations between the DFT and the low-energy solver is avoided by using the constrained G W scheme; and (2) the frequency dependent interactions emerging from the partial trace summation are successfully separated into a nonlocal part that is treated following ideas by Hirayama et al. and a local part treated nonperturbatively in the spirit of Casula et al. and are incorporated into the renormalization of the low-energy dispersion. The scheme is favorably tested on the example of SrVO3.
Correlation between liver function tests and metabolic syndrome in hepatitis-free elderly
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Hung-Sheng Shang
2015-01-01
Full Text Available Background: We aimed to investigate the relationship between liver function tests (LFTs and metabolic syndrome (MetS as several studies have shown positive correlations between some of the LFTs, including alanine aminotransferase (ALT and γ-glutamyl transpeptidase (γ-GT, and MetS but have not fully explored the same in the elderly. Owing to the progress in public health, the aging of the general population becomes a major issue. Design: We enrolled subjects aged over 60 years who underwent routine health checkups in a Health Screening Center after excluding subjects with a history of hepatitis B or C infection, excessive alcohol consumption, liver fibrosis, cirrhosis, acute hepatitis, diabetes, hypertension, dyslipidemia, cardiovascular disease, or receiving medications for these diseases. Finally, 9,282 participants were eligible for analysis. Statistical Analysis: All data were tested for normal distribution with the Kolmogorov-Smirnov test and for homogeneity of variances with the Levene′s test. A t-test was used to evaluate the differences between the two groups. Univariate and multivariate regressions were used to observe correlations between different parameters. Receiver operating characteristic curves of each LFT were used to predict MetS. Areas under curves and 95% confidence interval were also estimated and compared. Results: With the exception of aspartate aminotransferase and α-fetal protein, the results of LFTs, including total and direct bilirubin, alkaline phosphatase (ALP, ALT, and γ-GT, were altered in the group with MetS. Furthermore, the levels of γ-GT in men and ALP in women were independently associated with all MetS components and had the highest areas under receiver operating characteristic curves. Conclusion: Abnormal LFTs are highly correlated with MetS in the hepatitis-free elderly, with levels of γ-GT in men and ALP in women being the most important factors. LFTs may represent an auxiliary tool for the
Neural correlates of the popular music phenomenon: evidence from functional MRI and PET imaging
Energy Technology Data Exchange (ETDEWEB)
Chen, Qiaozhen [The Second Affiliated Hospital of Zhejiang University School of Medicine, Department of Psychiatry, Hangzhou (China); Zhejiang University Medical PET Center, Hangzhou (China); Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University, Hangzhou (China); Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou (China); The Second Affiliated Hospital of Zhejiang University School of Medicine, Department of Nuclear Medicine, Hangzhou, Zhejiang (China); Zhang, Ying; Hou, Haifeng; Du, Fenglei; Wu, Shuang; Chen, Lin; Shen, Yehua; Chao, Fangfang; Zhang, Hong; Tian, Mei [Zhejiang University Medical PET Center, Hangzhou (China); Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University, Hangzhou (China); Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou (China); The Second Affiliated Hospital of Zhejiang University School of Medicine, Department of Nuclear Medicine, Hangzhou, Zhejiang (China); Chung, June-key [Seoul National University Hospital, Department of Nuclear Medicine, Seoul (Korea, Republic of)
2017-06-15
Music can induce different emotions. However, its neural mechanism remains unknown. The aim of this study was to use functional magnetic resonance imaging (fMRI) and position emission tomography (PET) imaging for mapping of neural changes under the most popular music in healthy volunteers. Blood-oxygen-level-dependent (BOLD) fMRI and monoamine receptor PET imaging with {sup 11}C-N-methylspiperone ({sup 11}C-NMSP) were conducted under the popular music Gangnam Style and light music A Comme Amour in healthy subjects. PET and fMRI images were analyzed by using the Statistical Parametric Mapping software (SPM). Significantly increased fMRI BOLD signals were found in the bilateral superior temporal cortices, left cerebellum, left putamen and right thalamus cortex. Monoamine receptor availability was increased significantly in the left superior temporal gyrus and left putamen, but decreased in the bilateral superior occipital cortices under the Gangnam Style compared with the light music condition. Significant positive correlation was found between {sup 11}C-NMSP binding and fMRI BOLD signals in the left temporal cortex. Furthermore, increased {sup 11}C-NMSP binding in the left putamen was positively correlated with the mood arousal level score under the Gangnam Style condition. Popular music Gangnam Style can arouse pleasure experience and strong emotional response. The left putamen is positively correlated with the mood arousal level score under the Gangnam Style condition. Our results revealed characteristic patterns of brain activity associated with Gangnam Style, and may also provide more general insights into the music-induced emotional processing. (orig.)
Neural correlates of the popular music phenomenon: evidence from functional MRI and PET imaging.
Chen, Qiaozhen; Zhang, Ying; Hou, Haifeng; Du, Fenglei; Wu, Shuang; Chen, Lin; Shen, Yehua; Chao, Fangfang; Chung, June-Key; Zhang, Hong; Tian, Mei
2017-06-01
Music can induce different emotions. However, its neural mechanism remains unknown. The aim of this study was to use functional magnetic resonance imaging (fMRI) and position emission tomography (PET) imaging for mapping of neural changes under the most popular music in healthy volunteers. Blood-oxygen-level-dependent (BOLD) fMRI and monoamine receptor PET imaging with 11 C-N-methylspiperone ( 11 C-NMSP) were conducted under the popular music Gangnam Style and light music A Comme Amour in healthy subjects. PET and fMRI images were analyzed by using the Statistical Parametric Mapping software (SPM). Significantly increased fMRI BOLD signals were found in the bilateral superior temporal cortices, left cerebellum, left putamen and right thalamus cortex. Monoamine receptor availability was increased significantly in the left superior temporal gyrus and left putamen, but decreased in the bilateral superior occipital cortices under the Gangnam Style compared with the light music condition. Significant positive correlation was found between 11 C-NMSP binding and fMRI BOLD signals in the left temporal cortex. Furthermore, increased 11 C-NMSP binding in the left putamen was positively correlated with the mood arousal level score under the Gangnam Style condition. Popular music Gangnam Style can arouse pleasure experience and strong emotional response. The left putamen is positively correlated with the mood arousal level score under the Gangnam Style condition. Our results revealed characteristic patterns of brain activity associated with Gangnam Style, and may also provide more general insights into the music-induced emotional processing.
Correlated electron dynamics and memory in time-dependent density functional theory
International Nuclear Information System (INIS)
Thiele, Mark
2009-01-01
Time-dependent density functional theory (TDDFT) is an exact reformulation of the time-dependent many-electron Schroedinger equation, where the problem of many interacting electrons is mapped onto the Kohn-Sham system of noninteracting particles which reproduces the exact electronic density. In the Kohn-Sham system all non-classical many-body effects are incorporated in the exchange-correlation potential which is in general unknown and needs to be approximated. It is the goal of this thesis to investigate the connection between memory effects and correlated electron dynamics in strong and weak fields. To this end one-dimensional two-electron singlet systems are studied. At the same time these systems include the onedimensional helium atom model, which is an established system to investigate the crucial effects of correlated electron dynamics in external fields. The studies presented in this thesis show that memory effects are negligible for typical strong field processes. Here the approximation of the spatial nonlocality is of primary importance. For the photoabsorption spectra on the other hand the neglect of memory effects leads to qualitative and quantitative errors, which are shown to be connected to transitions of double excitation character. To develop a better understanding of the conditions under which memory effects become important quantum fluid dynamics has been found to be especially suitable. It represents a further exact reformulation of the quantum mechanic many-body problem which is based on hydrodynamic quantities such as density and velocity. Memory effects are shown to be important whenever the velocity field develops strong gradients and dissipative effects contribute. (orig.)
Larcombe, Stephanie J; Kennard, Chris; Bridge, Holly
2018-01-01
Repeated practice of a specific task can improve visual performance, but the neural mechanisms underlying this improvement in performance are not yet well understood. Here we trained healthy participants on a visual motion task daily for 5 days in one visual hemifield. Before and after training, we used functional magnetic resonance imaging (fMRI) to measure the change in neural activity. We also imaged a control group of participants on two occasions who did not receive any task training. While in the MRI scanner, all participants completed the motion task in the trained and untrained visual hemifields separately. Following training, participants improved their ability to discriminate motion direction in the trained hemifield and, to a lesser extent, in the untrained hemifield. The amount of task learning correlated positively with the change in activity in the medial superior temporal (MST) area. MST is the anterior portion of the human motion complex (hMT+). MST changes were localized to the hemisphere contralateral to the region of the visual field, where perceptual training was delivered. Visual areas V2 and V3a showed an increase in activity between the first and second scan in the training group, but this was not correlated with performance. The contralateral anterior hippocampus and bilateral dorsolateral prefrontal cortex (DLPFC) and frontal pole showed changes in neural activity that also correlated with the amount of task learning. These findings emphasize the importance of MST in perceptual learning of a visual motion task. Hum Brain Mapp 39:145-156, 2018. © 2017 Wiley Periodicals, Inc. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.
Correlated electron dynamics and memory in time-dependent density functional theory
Energy Technology Data Exchange (ETDEWEB)
Thiele, Mark
2009-07-28
Time-dependent density functional theory (TDDFT) is an exact reformulation of the time-dependent many-electron Schroedinger equation, where the problem of many interacting electrons is mapped onto the Kohn-Sham system of noninteracting particles which reproduces the exact electronic density. In the Kohn-Sham system all non-classical many-body effects are incorporated in the exchange-correlation potential which is in general unknown and needs to be approximated. It is the goal of this thesis to investigate the connection between memory effects and correlated electron dynamics in strong and weak fields. To this end one-dimensional two-electron singlet systems are studied. At the same time these systems include the onedimensional helium atom model, which is an established system to investigate the crucial effects of correlated electron dynamics in external fields. The studies presented in this thesis show that memory effects are negligible for typical strong field processes. Here the approximation of the spatial nonlocality is of primary importance. For the photoabsorption spectra on the other hand the neglect of memory effects leads to qualitative and quantitative errors, which are shown to be connected to transitions of double excitation character. To develop a better understanding of the conditions under which memory effects become important quantum fluid dynamics has been found to be especially suitable. It represents a further exact reformulation of the quantum mechanic many-body problem which is based on hydrodynamic quantities such as density and velocity. Memory effects are shown to be important whenever the velocity field develops strong gradients and dissipative effects contribute. (orig.)
GDNF plasma levels in spina bifida: correlation with severity of spinal damage and motor function.
Chiaretti, Antonio; Rendeli, Claudia; Antonelli, Alessia; Barone, Giuseppe; Focarelli, Benedetta; Tabacco, Fabrizia; Massimi, Luca; Ausili, Emanuele
2008-12-01
Glial-derived neurotrophic factor (GDNF) is one of several powerful survival factors for spinal motoneurons that play a key role in sprouting, synaptic plasticity, and reorganization after spinal cord damage. The aim of this study was to investigate the expression of GDNF in plasma of children with spina bifida (SB) and to determine its correlation with both the severity of spinal cord damage and the motor function of these patients. To measure the GDNF expression, we collected plasma samples from 152 children with SB and in 149 matched controls. Endogenous GDNF levels were quantified using a two-site immuno-enzymatic assay. The statistical analysis was performed using the Mann-Whitney two-tailed two-sample test. In children with SB the mean levels of GDNF (131.2 +/- 69.6 pg/mL) were significantly higher (p spine injury.
A cross-correlation-based estimate of the galaxy luminosity function
van Daalen, Marcel P.; White, Martin
2018-02-01
We extend existing methods for using cross-correlations to derive redshift distributions for photometric galaxies, without using photometric redshifts. The model presented in this paper simultaneously yields highly accurate and unbiased redshift distributions and, for the first time, redshift-dependent luminosity functions, using only clustering information and the apparent magnitudes of the galaxies as input. In contrast to many existing techniques for recovering unbiased redshift distributions, the output of our method is not degenerate with the galaxy bias b(z), which is achieved by modelling the shape of the luminosity bias. We successfully apply our method to a mock galaxy survey and discuss improvements to be made before applying our model to real data.
International Nuclear Information System (INIS)
Bello, J.A.; Fink, M.E.; Hilal, S.K.; Rose, E.A.; Reemtsma, K.
1987-01-01
Thirteen consecutive unselected patients with NYHA class 4 cardiac failure referred for cardiac transplantation underwent neurologic examination and cerebral blood flow measurement (rCBF) using the stable xenon enhanced CT method on a GE9800 system. Eleven men and two women were studied (mean age = 43.8 +- 6.1). On neurological examination, six of the patients demonstrated normal mental function; the remaining seven patients demonstrated memory, language, or learning impairment. There was no difference in mean cardiac output between the groups (4.9 L/min +- 1.68 vs. 4.2L/min +- 1.57). rCBF was significantly reduced in the impaired group. Cognitive impairment in patients with cardiac failure can be correlated with cerebral ischemia. Stable xenon CT measurement of rCBF in transplant candidates may help identify patients requiring more rapid transplantation to prevent permanent cerebral injury
Atlas of regional anatomy of the brain using MRI. With functional correlations
International Nuclear Information System (INIS)
Tamraz, J.C.
2006-01-01
The volume provides a unique review of the essential topographical anatomy of the brain from an MRI perspective, correlating high-quality anatomical plates with the corresponding high-resolution MRI images. The book includes a historical review of brain mapping and an analysis of the essential reference planes used for the study of the human brain. Subsequent chapters provide a detailed review of the sulcal and the gyral anatomy of the human cortex, guiding the reader through an interpretation of the individual brain atlas provided by high-resolution MRI. The relationship between brain structure and function is approached in a topographical fashion with analysis of the necessary imaging methodology and displayed anatomy. The central, perisylvian, mesial temporal and occipital areas receive special attention. Imaging of the core brain structures is included. An extensive coronal atlas concludes the book. (orig.)
Liquid direct correlation function, singlet densities and the theory of freezing
International Nuclear Information System (INIS)
March, N.H.; Tosi, M.P.
1981-04-01
We have examined the solutions for the singlet density rho(r) in the hierarchical equation connecting rho(r) with the liquid direct correlation function c(r). In addition to the homogeneous solution rho(r)=rhosub(liquid), we exhibit a periodic solution which can co-exist with the liquid solution. If the defining equation for this is linearized, we recover the bifurcation condition of Lovett and Buff. We stress the difference between the two treatments as that between first and second-order transitions. It turns out that the treatment presented here leads to the same periodic density as that derived, using the hypernetted chain approximation, by Ramakrishnan and Yussouff in their theory of freezing. Invoking that approximation is shown thereby to be inessential. (author)
Herschel-ATLAS: The Angular Correlation Function of Submillimetre Galaxies at High and Low Redshift
Maddox, S. J.; Dunne, L.; Rigby, E.; Eales, S.; Cooray, A.; Scott, D.; Peacock, J. A.; Negrello, M.; Smith, D. J. B.; Benford, D.;
2010-01-01
We present measurements of the angular correlation function of galaxies selected from the first field of the H-ATLAS survey. Careful removal of the background from galactic cirrus is essential, and currently dominates the uncertainty in our measurements. For our 250 micrometer-selected sample we detect no significant clustering, consistent with the expectation that the 250 pm-selected sources are mostly normal galaxies at z high redshift galaxies at z approx. 2-3 we detect significant strong clustering, leading to an estimate of r(0) approx. 7-11/h Mpc. The slope of our clustering measurements is very steep. delta approx. 2. The measurements are consistent with the idea that sub-mm sources consist of a low redshift population of normal galaxies and a high redshift population of highly clustered star-bursting galaxies.
Dynamical correlation functions of the quadratic coupling spin-Boson model
Zheng, Da-Chuan; Tong, Ning-Hua
2017-06-01
The spin-boson model with quadratic coupling is studied using the bosonic numerical renormalization group method. We focus on the dynamical auto-correlation functions {C}O(ω ), with the operator \\hat{O} taken as {\\hat{{{σ }}}}x, {\\hat{{{σ }}}}z, and \\hat{X}, respectively. In the weak-coupling regime α index and X is the boson displacement operator. Close to the spin flip point, the high frequency peak of {C}{{{σ }}x}(ω ) is broadened significantly and the line shape changes qualitatively, showing enhanced dephasing at the spin flip point. Project supported by the National Key Basic Research Program of China (Grant No. 2012CB921704), the National Natural Science Foundation of China (Grant No. 11374362), the Fundamental Research Funds for the Central Universities, China, and the Research Funds of Renmin University of China (Grant No. 15XNLQ03).
Ordinario, Donald Thomas
The natural neutron background rate is largely due to cosmic ray interactions in the atmosphere and the subsequent neutron emission from the interaction products. The neutron background is part of a larger cosmic radiation shower that also includes electrons, gamma rays, and muons. Since neutrons interact much differently than muons in building materials, the muon and neutron fluence rates in the natural background can be compared to the measured muon and neutron fluence rate when shielded by common building materials. The simultaneous measurement of muon and neutron fluence rates might allow for an earlier identification of man-made neutron sources, such as hidden nuclear materials. This study compares natural background neutron rates to computer simulated neutron rates shielded by common structural and building materials. The characteristic differences between neutrons and muons resulted in different attenuation properties under the same shielded conditions. Correlation functions between cosmic ray generated neutrons and muons are then used to predict neutron fluence rates in different urban environments.
libvdwxc: a library for exchange-correlation functionals in the vdW-DF family
Hjorth Larsen, Ask; Kuisma, Mikael; Löfgren, Joakim; Pouillon, Yann; Erhart, Paul; Hyldgaard, Per
2017-09-01
We present libvdwxc, a general library for evaluating the energy and potential for the family of vdW-DF exchange-correlation functionals. libvdwxc is written in C and provides an efficient implementation of the vdW-DF method and can be interfaced with various general-purpose DFT codes. Currently, the Gpaw and Octopus codes implement interfaces to libvdwxc. The present implementation emphasizes scalability and parallel performance, and thereby enables ab initio calculations of nanometer-scale complexes. The numerical accuracy is benchmarked on the S22 test set whereas parallel performance is benchmarked on ligand-protected gold nanoparticles ({{Au}}144{({{SC}}11{{NH}}25)}60) up to 9696 atoms.
Correlation functions in quantum field theory and in condensed matter physics
International Nuclear Information System (INIS)
Mabilat, H.
1998-01-01
Two main formalisms are used to calculate the correlation functions in the quantum field theory: the operational formalism and the path integral formalism. In a first part both are used in parallel in the framework of the field theory at the thermal equilibrium, applied to the particles physic, to detect the integration outline. The following two discussions present a whole demonstration of the real-time formalism. In the second part the operational formalism is used, alone, to discuss on the non-equilibrium notion, which has a great importance in the quark-gluon plasma physic. In the third part, the path integral is used to study the bosonic Hubbard model, in the framework of the condensed matter physic. The thesis describes a new discretization of the path integral for numerical simulations. (A.L.B.)
Neufeld, J; Sinke, C; Dillo, W; Emrich, H M; Szycik, G R; Dima, D; Bleich, S; Zedler, M
2012-01-01
In auditory-visual synaesthesia, all kinds of sound can induce additional visual experiences. To identify the brain regions mainly involved in this form of synaesthesia, functional magnetic resonance imaging (fMRI) has been used during non-linguistic sound perception (chords and pure tones) in synaesthetes and non-synaesthetes. Synaesthetes showed increased activation in the left inferior parietal cortex (IPC), an area involved in multimodal integration, feature binding and attention guidance. No significant group-differences could be detected in area V4, which is known to be related to colour vision and form processing. The results support the idea of the parietal cortex acting as sensory nexus area in auditory-visual synaesthesia, and as a common neural correlate for different types of synaesthesia. Copyright © 2011 Elsevier Ltd. All rights reserved.
Kaoui, Fawzi; Rocca, Dario
2016-01-01
A new approach was recently presented to compute correlation energies within the random phase approximation using Lanczos chains and an optimal basis set (Rocca 2014 J. Chem. Phys. 140 18A501). This novel method avoids the explicit calculation of conduction states and represents linear response functions on a compact auxiliary basis set obtained from the diagonalization of an approximate dielectric matrix that contains only the kinetic energy contribution. Here, we extend this formalism, originally implemented for molecular systems, to treat periodic solids. In particular, the approximate dielectric matrix used to build the auxiliary basis set is generalized to avoid unphysical negative gaps, that make the model inefficient. The numerical convergence of the method is discussed and the accuracy is demonstrated considering a set including three covalently bonded (C, Si, and SiC) and three weakly bonded (Ne, Ar, and Kr) solids.
Fried, Ronna; Joshi, Gagan; Bhide, Pradeep; Pope, Amanda; Galdo, Maribel; Koster, Ariana; Chan, James; Faraone, Stephen V; Biederman, Joseph
2016-10-01
To examine the unique neuropsychological presentation in adults with high functioning autism spectrum disorders (HF-ASD) by comparison with adults with attention deficit hyperactivity disorder (ADHD). Adults with ASD referred to a specialty clinic (n=26) were compared to two non-ASD groups with (n=52) and without (n=52) ADHD of similar age and sex. No differences in IQ were found. Subjects with HF-ASD were significantly more impaired than both comparison groups in processing speed, cognitive flexibility and sight words. Subjects with HF-ASD were more impaired than controls in working memory, but not the ADHD group. These findings suggest that there may be specific neuropsychological correlates of HF-ASD differing from ADHD that could have significant implications for identifying individuals at risk for ASD.
Jensen, Chad D; Duraccio, Kara M; Carbine, Kaylie A; Barnett, Kimberly A; Kirwan, C Brock
2017-06-01
To examine associations between motivational impact of palatable foods and neural activity in brain regions involved in inhibitory control among adolescents. Thirty-four adolescents aged 14-20 years underwent functional magnetic resonance imaging while viewing images of high- and low-energy foods. Participants completed the Power of Food Scale (PFS). Whole-brain analyses of variance tested for neural activation differences and correlations between brain activation and PFS scores were tested. We found an interaction between food type (high energy vs. low energy) and PFS scores in the right dorsolateral prefrontal cortex and right inferior parietal lobule. We also found that PFS scores correlated negatively with activation to high-energy foods in prefrontal cortical and parietal regions. These findings suggest that individuals with high motivation for high-energy foods also demonstrate lower neural activation in inhibition-related brain regions when viewing images of high-energy foods, indicating that they may have difficulty inhibiting consumption impulses. © The Author 2016. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com
Directory of Open Access Journals (Sweden)
Maite Garaigordobil
2013-05-01
Full Text Available The goals of the study were to analyze differences as a function of gender, age, and educational level in sexism and alexithymia in a nonclinical and in a clinical sample, and to explore the relation between these constructs. A descriptive and correlational cross-sectional methodology was used. The Ambivalent Sexism Inventory (Glick & Fiske, 1996 and the Toronto Alexithymia Scale (Parker et al. 1993 were administered. The sample comprised 989 participants from the Basque Country, aged between 18 and 65 years. The results revealed: 1 Significantly higher scores in the males in sexism (hostile, benevolent, and ambivalent and in alexithymia (difficulties to express emotions and external-oriented thinking in both samples; in the total alexithymia score, the males had significantly higher scores only in the nonclinical sample; 2 As of 55 years of age, a significant increase in benevolent and ambivalent sexism, and in difficulties to identify emotions, external-oriented thinking, and in the total alexithymia score were observed (only in the nonclinical sample; however, no changes with age were observed in hostile sexism and in difficulties to express emotions; 3 A decrease in sexism and alexithymia as the educational level increased; and 4 Significant positive correlations between sexism and alexithymia.
Correlation of neurocognitive function and brain parenchyma volumes in children surviving cancer
Reddick, Wilburn E.; White, Holly A.; Glass, John O.; Mulhern, Raymond K.
2002-04-01
This research builds on our hypothesis that white matter damage and associated neurocognitive symptoms, in children treated for cancer with cranial spinal irradiation, spans a continuum of severity that can be reliably probed using non-invasive MR technology. Quantitative volumetric assessments of MR imaging and psychological assessments were obtained in 40 long-term survivors of malignant brain tumors treated with cranial irradiation. Neurocognitive assessments included a test of intellect (Wechsler Intelligence Test for Children, Wechsler Adult Intelligence Scale), attention (Conner's Continuous Performance Test), and memory (California Verbal Learning Test). One-sample t-tests were conducted to evaluate test performance of survivors against age-adjusted scores from the test norms; these analyses revealed significant impairments in all apriori selected measures of intelligence, attention, and memory. Partial correlation analyses were performed to assess the relationships between brain tissues volumes (normal appearing white matter (NAWM), gray matter, and CSF) and neurocognitive function. Global intelligence (r = 0.32, p = 0.05) and global attentional (r = 0.49, p memory was significantly positively correlated with overall brain parenchyma (r = 0.38, p = 0.04). We conclude that quantitative assessment of MR examinations in survivors of childhood cancer treated with cranial irradiation reveal that loss of NAWM is associated with decreased intellectual and attentional deficits, whereas overall parenchyma loss, as reflected by increased CSF and decreased white matter, is associated with memory-related deficits.
Correlation between NK function and response to trastuzumab in metastatic breast cancer patients
Directory of Open Access Journals (Sweden)
Spadi Rosella
2008-05-01
Full Text Available Abstract Background Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antibody-dependent cellular cytotoxicity (ADCC by triggering FcγRIII on natural killer (NK cells. This study addresses the correlation between overall NK function and trastuzumab's clinical activity. Subjects and methods Clinical and immunological responses were assessed in 26 patients receiving trastuzumab monotherapy as maintenance management after chemotherapy (8 mg/kg load and then standard doses of 6 mg/kg every 3 weeks. Cytotoxic activity against the MHC class I-negative standard NK target K562 cell line and HER2-specific ADCC against a trastuzumab-coated Her2-positive SKBR3 cell line were assessed in peripheral blood mononuclear cells (PBMC harvested after the first standard dose. After six months, seventeen patients were scored as responders and nine as non-responders according to the RECIST criteria, while Progression-Free Survival (PFS was calculated during a 12 months follow-up. Results The responders had significantly higher levels of both NK and ADCC activities (p Conclusion One of the mechanisms of action of trastuzumab is NK cell-mediated ADCC lysis of the Her2-positve target cell. We show here that its potency is correlated with the short-term response to treatment, whereas longer protection against tumor expansion seems to be mediated by pure NK activity.
Behavioral and neural correlates of executive functioning in musicians and non-musicians.
Zuk, Jennifer; Benjamin, Christopher; Kenyon, Arnold; Gaab, Nadine
2014-01-01
Executive functions (EF) are cognitive capacities that allow for planned, controlled behavior and strongly correlate with academic abilities. Several extracurricular activities have been shown to improve EF, however, the relationship between musical training and EF remains unclear due to methodological limitations in previous studies. To explore this further, two experiments were performed; one with 30 adults with and without musical training and one with 27 musically trained and untrained children (matched for general cognitive abilities and socioeconomic variables) with a standardized EF battery. Furthermore, the neural correlates of EF skills in musically trained and untrained children were investigated using fMRI. Adult musicians compared to non-musicians showed enhanced performance on measures of cognitive flexibility, working memory, and verbal fluency. Musically trained children showed enhanced performance on measures of verbal fluency and processing speed, and significantly greater activation in pre-SMA/SMA and right VLPFC during rule representation and task-switching compared to musically untrained children. Overall, musicians show enhanced performance on several constructs of EF, and musically trained children further show heightened brain activation in traditional EF regions during task-switching. These results support the working hypothesis that musical training may promote the development and maintenance of certain EF skills, which could mediate the previously reported links between musical training and enhanced cognitive skills and academic achievement.
Segregation of acetylcholine and GABA in the rat superior cervical ganglia: functional correlation.
Directory of Open Access Journals (Sweden)
Diana eElinos
2016-04-01
Full Text Available Sympathetic neurons have the capability to segregate their neurotransmitters (NTs and co-transmitters to separate varicosities of single axons; furthermore, in culture, these neurons can even segregate classical transmitters. In vivo sympathetic neurons employ acetylcholine (ACh and other classical NTs such as gamma aminobutyric acid (GABA. Herein, we explore whether these neurons in vivo segregate these classical NTs in the superior cervical ganglia of the rat. We determined the topographical distribution of GABAergic varicosities, somatic GABAA receptor, as well as the regional distribution of the segregation of ACh and GABA. We evaluated possible regional differences in efficacy of ganglionic synaptic transmission, in the sensitivity of GABAA receptor to GABA and to the competitive antagonist picrotoxin (PTX. We found that sympathetic preganglionic neurons in vivo do segregate ACh and GABA. GABAergic varicosities and GABAA receptor expression showed a rostro-caudal gradient along ganglia; in contrast, segregation exhibited a caudo-rostral gradient. These uneven regional distributions in expression of GABA, GABAA receptors, and level segregation correlate with stronger synaptic transmission found in the caudal region. Accordingly, GABAA receptors of rostral region show larger sensitivity to GABA and PTX. These results suggest the presence of different types of GABAA receptors in each region that result in a different regional levels of endogenous GABA inhibition. Finally, we discuss a possible correlation of these different levels of GABA modulation and the function of the target organs innervated by rostral and caudal ganglionic neurons.
Wang, Pei-Ning; Chou, Kun-Hsien; Chang, Ni-Jung; Lin, Ker-Neng; Chen, Wei-Ta; Lan, Gong-Yau; Lin, Ching-Po; Lirng, Jiing-Feng
2014-04-01
Degeneration of the corpus callosum (CC) is evident in the pathogenesis of Alzheimer's disease (AD). However, the correlation of microstructural damage in the CC on the cognitive performance of patients with amnestic mild cognitive impairment (aMCI) and AD dementia is undetermined. We enrolled 26 normal controls, 24 patients with AD dementia, and 40 single-domain aMCI patients with at least grade 1 hippocampal atrophy and isolated memory impairment. Diffusion tensor imaging (DTI) with fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (DA), and radial diffusivity (DR) were measured. The entire CC was parcellated based on fiber trajectories to specific cortical Brodmann areas using a probabilistic tractography method. The relationship between the DTI measures in the subregions of the CC and cognitive performance was examined. Although the callosal degeneration in the patients with aMCI was less extended than in the patients with AD dementia, degeneration was already exhibited in several subregions of the CC at the aMCI stage. Scores of various neuropsychological tests were correlated to the severity of microstructural changes in the subregional CC connecting to functionally corresponding cortical regions. Our results confirm that CC degeneration is noticeable as early as the aMCI stage of AD and the disconnection of the CC subregional fibers to the corresponding Brodmann areas has an apparent impact on the related cognitive performance. Copyright © 2013 Wiley Periodicals, Inc.
Irreducible Greens' Functions method in the theory of highly correlated systems
International Nuclear Information System (INIS)
Kuzemsky, A.L.
1994-09-01
The self-consistent theory of the correlation effects in Highly Correlated Systems (HCS) is presented. The novel Irreducible Green's Function (IGF) method is discussed in detail for the Hubbard model and random Hubbard model. The interpolation solution for the quasiparticle spectrum, which is valid for both the atomic and band limit is obtained. The (IGF) method permits to calculate the quasiparticle spectra of many-particle systems with the complicated spectra and strong interaction in a very natural and compact way. The essence of the method deeply related to the notion of the Generalized Mean Fields (GMF), which determine the elastic scattering corrections. The inelastic scattering corrections leads to the damping of the quasiparticles and are the main topic of the present consideration. The calculation of the damping has been done in a self-consistent way for both limits. For the random Hubbard model the weak coupling case has been considered and the self-energy operator has been calculated using the combination of the IGF method and Coherent Potential Approximation (CPA). The other applications of the method to the s-f model, Anderson model, Heisenberg antiferromagnet, electron-phonon interaction models and quasiparticle tunneling are discussed briefly. (author). 79 refs
Energy Technology Data Exchange (ETDEWEB)
Alunni, Jean-Philippe; Otal, Philippe; Rousseau, Herve; Chabbert, Valerie [CHU Rangueil, Department of Radiology, Toulouse (France); Degano, Bruno; Tetu, Laurent; Didier, Alain [CHU Larrey, Department of Pneumology, Toulouse (France); Arnaud, Catherine [CHU Rangueil, Department of Methods in Clinical Research, Toulouse (France); Blot-Souletie, Nathalie [CHU Rangueil, Department of Cardiology, Toulouse (France)
2010-05-15
To compare cardiac MRI with right heart catheterisation in patients with pulmonary hypertension (PH) and to evaluate its ability to assess PH severity. Forty patients were included. MRI included cine and phase-contrast sequences, study of ventricular function, cardiac cavity areas and ratios, position of the interventricular septum (IVS) in systole and diastole, and flow measurements. We defined four groups according to the severity of PH and three groups according to IVS position: A, normal position; B, abnormal in diastole; C, abnormal in diastole and systole. IVS position was correlated with pulmonary artery pressures and PVR (pulmonary vascular resistance). Median pulmonary artery pressures and resistance were significantly higher in patients with an abnormal septal position compared with those with a normal position. Correlations were good between the right ventricular ejection fraction and PVR, right ventricular end-systolic volume and PAP, percentage of right ventricular area change and PVR, and diastolic and systolic ventricular area ratio and PVR. These parameters were significantly associated with PH severity. Cardiac MRI can help to assess the severity of PH. (orig.)
New correlation potential for the local-spin-density functional formalism. II
International Nuclear Information System (INIS)
Kolar, M.; Farkas, L.
1982-01-01
Using the new parameterization for the correlation potential which seems to be the best that is at present available within the local-spin-density (LSD) functional formalism, the Fermi contact term in light atoms (up to Ni) is calculated. Although the overall improvement of the previous LSD results is obtained, discrepancy between theory and experiment remains rather large. It seems that the local approximation for exchange and correlation fails to predict such quantities as magnetic-moment density near the nucleus. It is also shown that the self-interaction correction does not remedy this failure. Further, the effect of the nonzero nuclear radius is investigated and found to be most important in the lightest atoms (e.g. a factor of 0.664 appears in the case of Li). This fact was omitted in all previous calculations and throws doubt on the reported excellent agreement of the results of many-body perturbation theory with experiment. It was also verified that the contact approximation of the Fermi contact term is really good enough. (author)
A time-correlation function approach to nuclear dynamical effects in X-ray spectroscopy
Karsten, Sven; Bokarev, Sergey I.; Aziz, Saadullah G.; Ivanov, Sergei D.; Kühn, Oliver
2017-06-01
Modern X-ray spectroscopy has proven itself as a robust tool for probing the electronic structure of atoms in complex environments. Despite working on energy scales that are much larger than those corresponding to nuclear motions, taking nuclear dynamics and the associated nuclear correlations into account may be of importance for X-ray spectroscopy. Recently, we have developed an efficient protocol to account for nuclear dynamics in X-ray absorption and resonant inelastic X-ray scattering spectra [Karsten et al., J. Phys. Chem. Lett. 8, 992 (2017)], based on ground state molecular dynamics accompanied with state-of-the-art calculations of electronic excitation energies and transition dipoles. Here, we present an alternative derivation of the formalism and elaborate on the developed simulation protocol using gas phase and bulk water as examples. The specific spectroscopic features stemming from the nuclear motions are analyzed and traced down to the dynamics of electronic energy gaps and transition dipole correlation functions. The observed tendencies are explained on the basis of a simple harmonic model, and the involved approximations are discussed. The method represents a step forward over the conventional approaches that treat the system in full complexity and provides a reasonable starting point for further improvements.
Behavioral and neural correlates of executive functioning in musicians and non-musicians.
Directory of Open Access Journals (Sweden)
Jennifer Zuk
Full Text Available Executive functions (EF are cognitive capacities that allow for planned, controlled behavior and strongly correlate with academic abilities. Several extracurricular activities have been shown to improve EF, however, the relationship between musical training and EF remains unclear due to methodological limitations in previous studies. To explore this further, two experiments were performed; one with 30 adults with and without musical training and one with 27 musically trained and untrained children (matched for general cognitive abilities and socioeconomic variables with a standardized EF battery. Furthermore, the neural correlates of EF skills in musically trained and untrained children were investigated using fMRI. Adult musicians compared to non-musicians showed enhanced performance on measures of cognitive flexibility, working memory, and verbal fluency. Musically trained children showed enhanced performance on measures of verbal fluency and processing speed, and significantly greater activation in pre-SMA/SMA and right VLPFC during rule representation and task-switching compared to musically untrained children. Overall, musicians show enhanced performance on several constructs of EF, and musically trained children further show heightened brain activation in traditional EF regions during task-switching. These results support the working hypothesis that musical training may promote the development and maintenance of certain EF skills, which could mediate the previously reported links between musical training and enhanced cognitive skills and academic achievement.
Suttorp, L.G.
1992-01-01
The correlations of the electric potential fluctuations in a classical one-component plasma are studied for large distances between the observation points. The two-point correlation function for these fluctuations is known to decay slowly for large distances, even if exponential clustering holds for
Zhang, Jihui; Lamers, Femke; Hickie, Ian B; He, Jian-Ping; Feig, Emily; Merikangas, Kathleen R
2013-05-01
Recent studies have suggested that nonrestorative sleep (NRS) symptoms may be distinct from nocturnal insomnia symptoms (NIS). However, there is limited information on the demographic, medical, and biologic correlates of NRS independent from NIS in the general population. This report presents the sociodemographic correlates, patterns of comorbidity with other sleep and physical disorders, C-reactive protein (CRP) levels, and general productivity associated with NIS and NRS in a nationally representative sample of US adults. National Health and Nutrition Examination Survey (NHANES). The 2005-2008 surveys of the general population in the United States. There were 10,908 individuals (20 years or older). N/A. Respondents were classified by the presence or absence of NIS and NRS. Compared with those without insomnia symptoms, respondents with NIS were older and had lower family income and educational levels than those with NRS. In addition, there was a significant association between NIS and cardiovascular disease, whereas NRS was associated with other primary sleep disorders (including habitual snoring, sleep apnea, and restless legs syndrome), respiratory diseases (emphysema and chronic bronchitis), thyroid disease, and cancer as well as increased CRP levels. In addition, the study participants with NRS only reported poorer scores on the Functional Outcomes of Sleep Questionnaire (FOSQ) than those without insomnia symptoms or those with NIS only. These findings suggest that there are substantial differences between NIS and NRS in terms of sociodemographic factors, comorbidity with other sleep and physical disorders, increased CRP level, and functional impairment. An inflammatory response might play a unique role in the pathogenesis of NRS.
Disentangling interacting dark energy cosmologies with the three-point correlation function
Moresco, Michele; Marulli, Federico; Baldi, Marco; Moscardini, Lauro; Cimatti, Andrea
2014-10-01
We investigate the possibility of constraining coupled dark energy (cDE) cosmologies using the three-point correlation function (3PCF). Making use of the CODECS N-body simulations, we study the statistical properties of cold dark matter (CDM) haloes for a variety of models, including a fiducial ΛCDM scenario and five models in which dark energy (DE) and CDM mutually interact. We measure both the halo 3PCF, ζ(θ), and the reduced 3PCF, Q(θ), at different scales (2 appears flat at small scales (for all redshifts) and at low redshifts (for all scales), while it builds up the characteristic V-shape anisotropy at increasing redshifts and scales. With respect to the ΛCDM predictions, cDE models show lower (higher) values of the halo 3PCF for perpendicular (elongated) configurations. The effect is also scale-dependent, with differences between ΛCDM and cDE models that increase at large scales. We made use of these measurements to estimate the halo bias, that results in fair agreement with the one computed from the two-point correlation function (2PCF). The main advantage of using both the 2PCF and 3PCF is to break the bias-σ8 degeneracy. Moreover, we find that our bias estimates are approximately independent of the assumed strength of DE coupling. This study demonstrates the power of a higher order clustering analysis in discriminating between alternative cosmological scenarios, for both present and forthcoming galaxy surveys, such as e.g. Baryon Oscillation Spectroscopic Survey and Euclid.
Yamagata, Momoko; Ikezoe, Tome; Kamiya, Midori; Masaki, Mitsuhiro; Ichihashi, Noriaki
2017-01-01
Sample entropy (SampEn) is an analysis to evaluate movement complexity of the center of pressure (COP). A lower value of SampEn indicates lower complexity of COP variability, that is, rigidity, and lower degrees of freedom. Previous studies reported the association of increased SampEn with improved standing balance ability in young subjects. However, no studies have examined these relationships among older adults. Thus, we aimed to investigate the relationship between SampEn and standing balance ability in older adults. The subjects were 33 institutionalized older adults (aged 82.2±6.5 years). COP during static standing was measured. The standard deviation (SD) values of COP and SampEn in the sagittal and frontal planes were calculated using time series data. One-leg standing test (OLST), functional reach (FR) test, and lateral reach (LR) test were also measured to evaluate standing balance ability. OLST, FR, and LR were 6.5±8.3 s, 19.8±5.9 cm, and 18.2±6.4 cm, respectively. Pearson correlation analysis revealed that SampEn in the sagittal plane significantly correlated with OLST ( r =-0.35) and FR ( r =-0.36). However, SampEn in the frontal plane and SD of COP in both sagittal and frontal planes had no relationship with any of the clinical balance tests. Lower SampEn implies rigidity for postural control. In the present study, it was found that lower SampEn in the sagittal plane was related to a higher balance function, which suggests that older adults utilized body rigidity to maintain postural stability as a compensative strategy.
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Jacqueline eJonklaas
2015-06-01
Full Text Available The aim of this study was to determine whether there was a correlation between salivary symptoms and salivary functioning following radioiodine therapy. Fifteen patients receiving radioactive iodine therapy for differentiated thyroid cancer completed a questionnaire assessing their salivary and nasal symptoms and underwent salivary scanning prior to therapy and 3 and 12 months after therapy. Measures of salivary gland accumulation and secretion were correlated with scores of salivary and nasal symptomatology. The mean number of salivary, nasal, and total symptoms at 3 months increased significantly over the number of symptoms at baseline by 3.7, 2.7, and 6.3 symptoms respectively (p values 0.001, 0.0046, and <0.001. The mean right parotid gland accumulation and secretion of radioisotope declined significantly at 3 months, compared with baseline. There was no association between the increase in salivary, nasal, or total symptoms and the change in scintigraphy measures. The increases in nasal and total symptoms were significant in those with co-existent Hashimoto’s disease, compared with those without this condition (p values 0.01 and 0.04. Nasal symptoms decreased (p value 0.04 in those who used sour candies, compared with those who did not. Increasing body mass index was significantly associated with increasing nasal symptoms (p value 0.05. Greater decline in salivary parameters at 3 months compared with baseline was generally associated with heavier body weight, decreased thyroid cancer stage, absence of Hashimoto’s thyroiditis, and pre-menopausal status. Although salivary and nasal symptoms increased and salivary scintigraphy parameters decreased after radioiodine therapy, the variables associated with symptoms and changes in salivary scan parameters differed. A better understanding of the relationship between salivary gland symptoms and functioning, and the factors affecting susceptibility to salivary and nasal damage after radioiodine
Correlation study of podocyte injur y and kidney function in patients with acute kidney injur y
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You-Gang Feng
2016-11-01
Full Text Available Objective: To investigate the correlation between the podocyte injury indexes in urine such as nephrin, desmin, P-cadherin, podocin, podocalyxin and CD2-associated protein (CD2AP and the kidney function in patients with acute kidney injury (AKI. Methods: A total of 120 severe postsurgical patients treated in the Intensive Care Unit of our hospital from May 2012 to October 2015 were selected and divided into AKI group (n = 38 and non-AKI group (n = 82 according to the diagnostic criteria of AKI. After admission to the Intensive Care Unit for 24 h, their blood samples were collected to detect the contents of serum creatinine (Scr, serum urea (SUrea, b2-microglobulin (b2-MG and cystatin C (Cys-C, and urine samples were collected to detect the contents of kidney injury molecule-1 (KIM-1, liver-type fatty acid binding protein (L-FABP, Netrin-1, nephrin, desmin, P-cadherin, podocin, podocalyxin and CD2AP. Results: For patients in AKI group, the contents of Scr, SUrea, b2-MG and Cys-C in their blood samples and the contents of KIM-1, L-FABP, Netrin-1, nephrin, desmin, Pcadherin, podocin, podocalyxin and CD2AP in their urine samples were both significantly higher than those in non-AKI group. The contents of nephrin, desmin, P-cadherin, podocin, podocalyxin and CD2AP in urine samples and contents of Scr, SUrea, b2-MG, Cys-C and neutrophil gelatinase associated lipocalin in blood samples were positively correlated with the contents of KIM-1, L-FABP, and Netrin-1 in urine. Conclusions: Contents of podocyte injury molecules in urine of patients with acute kidney injury such as nephrin, desmin, P-cadherin, podocin, podocalyxin and CD2AP raised remarkably and the changes were consistent with the changes of kidney function indexes in the blood and urine samples.
Directory of Open Access Journals (Sweden)
Shameela .T .V
2015-12-01
Full Text Available Background: Among health care workers the highest level of work related back injuries are more affected in nurses. There were many studies done to assess low back pain by using different tools. So this study aimed to identify the prevalence low back pain disability among female nursing professionals and the association between BMI, functional reach test and low back pain, so that a better tool can be used during the clinical examination for the betterment of the patient. The objective of the study is to identify the prevalence of low back pain disability, the association of Low Back Pain(LBP with BMI and functional reach test among female nursing professionals. Methods: A total of 256 subjects were assessed for disability due to back pain using OswestryLBP Disability Questionnaire and the prevalence of disability was determined. The sit and reach test, forward reach test and their BMI were calculated for those who had a disability score of 20 and above (n=87. Results: Data was analyzed using Pearson’s correlation.The study result showed a significant correlation (p=0.03 of sit and reach test with low back pain disability scores. There was a negative correlationseen among BMI and LBP disability score forward reach test and LBP disability score, and BMI and no low back pain disability score. Conclusion: The prevalence of LBP disability among nursing professionals was 33.9%. This study suggest that sit and reach test can be used as an indicator of low back pain. Whereas BMI and forward reach test do not indicate low back pain.
Measuring the height-to-height correlation function of corrugation in suspended graphene
International Nuclear Information System (INIS)
Kirilenko, D.A.; Brunkov, P.N.
2016-01-01
Nanocorrugation of 2D crystals is an important phenomenon since it affects their electronic and mechanical properties. The corrugation may have various sources; one of them is flexural phonons that, in particular, are responsible for the thermal conductivity of graphene. A study of corrugation of just the suspended graphene can reveal much of valuable information on the physics of this complicated phenomenon. At the same time, the suspended crystal nanorelief can hardly be measured directly because of high flexibility of the 2D crystal. Moreover, the relief portion related to rapid out-of-plane oscillations (flexural phonons) is also inaccessible by such measurements. Here we present a technique for measuring the Fourier components of the height–height correlation function H(q) of suspended graphene which includes the effect of flexural phonons. The technique is based on the analysis of electron diffraction patterns. The H(q) is measured in the range of wavevectors q≈0.4–4.5 nm −1 . At the upper limit of this range H(q) does follow the T/κq 4 law. So, we measured the value of suspended graphene bending rigidity κ=1.2±0.4 eV at ambient temperature T≈300 K. At intermediate wave vectors, H(q) follows a slightly weaker exponent than theoretically predicted q −3.15 but is closer to the results of the molecular dynamics simulation. At low wave vectors, the dependence becomes even weaker, which may be a sign of influence of charge carriers on the dynamics of undulations longer than 10 nm. The technique presented can be used for studying physics of flexural phonons in other 2D materials. - Highlights: • A technique for measuring free-standing 2D crystal corrugation is proposed. • The height-to-height correlation function of the suspended graphene corrugation is measured. • Various parameters of the intrinsic graphene properties are experimentally determined.