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Sample records for lee russell mcdowell

  1. Russell-Silver syndrome

    Science.gov (United States)

    Silver-Russell syndrome; Silver syndrome; RSS; Russell-Silver syndrome ... One in 10 children with this syndrome has a problem involving chromosome 7. In other people with the syndrome, it may affect chromosome 11. Most of the time, it ...

  2. De dualismos y domesticaciones: Davidson, Mcdowell y Hegel

    OpenAIRE

    Luis Guzmán

    2016-01-01

    El renacimiento del interés por Hegel en el mundo filosófico se apoya en varios puntos: la superación del dualismo entre el esquema conceptual y el contenido (Davidson, McDowell), la disipación del mito de lo dado (Sellars, Quine) y el inferencialismo (Brandom). En relación con el primer punto, John McDowell intenta superar aquel dualismo, echando mano de un Hegel cuya retórica requiere de una domesticación. Se intenta iluminar el alcance y algunas limitaciones de esta propuesta, en su intent...

  3. De dualismos y domesticaciones: Davidson, Mcdowell y Hegel

    Directory of Open Access Journals (Sweden)

    Luis Guzmán

    2016-01-01

    Full Text Available El renacimiento del interés por Hegel en el mundo filosófico se apoya en varios puntos: la superación del dualismo entre el esquema conceptual y el contenido (Davidson, McDowell, la disipación del mito de lo dado (Sellars, Quine y el inferencialismo (Brandom. En relación con el primer punto, John McDowell intenta superar aquel dualismo, echando mano de un Hegel cuya retórica requiere de una domesticación. Se intenta iluminar el alcance y algunas limitaciones de esta propuesta, en su intento por desmontar la filosofía del permanente movimiento entre el mito de lo dado o la inmediatez, por un lado, y el coherentismo, por el otro.

  4. Silver-Russell syndrome

    Directory of Open Access Journals (Sweden)

    Shohela Akhter

    2016-08-01

    Full Text Available Silver-Russell syndrome is clinically and genetically a heterogeneous disorder. In most of the cases, etiology is unknown, only in 10% cases defect in chromosome 7 is identified. It bas distinctive facial features and asymmetric limbs. Most predominant symptom is growth failure. A case of Silver-Russell syndrome reported here who presented with growth failure, hemihypertrophy ofleft side oftbe body, dysmorphic facial profile and difficulty in speech. Counseling was done with the parents regarding the etiology, progression and outcome of the disease.

  5. Russell, Prof. John

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Honorary. Russell, Prof. John. Date of birth: 31 October 1872. Date of death: 12 July 1965. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. Theory Of Evolution. Posted on 23 January 2018. Joint Statement by the Three Science Academies of India on the ...

  6. Henry Norris Russell's Toronto Lectures

    Science.gov (United States)

    Devorkin, D. H.

    1996-12-01

    In February 1924, at the invitation of C. A. Chant, Russell presented a set of 14 public lectures on the state of astronomy and astrophysics. Designed to be inspirational, they also reveal Russell's contemporary views on the state of astrophysics as well as his sense of proper practice in astronomy. During his visit, Russell was interviewed by local reporters who asked his opinion about building a large observatory, one of Chant's major projects. What Russell had to say about such ventures did not please Chant one bit.

  7. Conceptual schemes and empiricism: what Davidson saw and McDowell missed

    Directory of Open Access Journals (Sweden)

    Jesús Coll Marmol

    2009-12-01

    Full Text Available En este artículo examino las posiciones de McDowell y Davidson acerca del dualismo de esquema y contenido. Defiendo que este dualismo no puede recuperarse de las críticas de Davidson incluso en la sugestiva forma defendida por McDowell. Defiendo que McDowell falla al evaluar el verdadero alcance y significado de los argumentos davidsonianos y que su empirismo mínimo no puede evitar algunos de los problemas que otras posiciones empiristas muestran

  8. Getting It Right in Ethical Experience: John McDowell and Virtue Ethics

    DEFF Research Database (Denmark)

    Christensen, Anne-Marie Søndergaard

    2009-01-01

    cannot understand the judgment resulting from virtue without drawing on that very perspective. However, McDowell's focus on the passive taking in of reasons in ethical experience and his idea of the silencing of wrong reasons lead us to three related problems. The first is that he cannot account...

  9. Book Review: Maximilian de Gaynesfordl John McDowell . Polity, 2004

    African Journals Online (AJOL)

    Book Review: Maximilian de Gaynesfordl John McDowell. Polity, 2004. Daniel Whiting. Abstract. No Abstract Available Philosophical Papers Vol.34(1) 2005: 137-142. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  10. RESTRICTIVE CARDIOMYOPATHY AND SECONDARY CONGESTIVE HEART FAILURE IN A MCDOWELL'S CARPET PYTHON (MORELIA SPILOTA MCDOWELLI).

    Science.gov (United States)

    Schilliger, Lionel; Chetboul, Valérie; Damoiseaux, Cécile; Nicolier, Alexandra

    2016-12-01

    Echocardiography is an established and noninvasive diagnostic tool used in herpetologic cardiology. Various cardiac lesions have been previously described in reptiles with the exception of restrictive cardiomyopathy. In this case report, restrictive cardiomyopathy and congestive heart failure associated with left atrial and sinus venosus dilation were diagnosed in a 2-yr-old captive lethargic McDowell's carpet python ( Morelia spilota mcdowelli), based on echocardiographic, Doppler, and histopathologic examinations. This cardiomyopathy was also associated with thrombosis within the sinus venosus.

  11. William Russell on Schools in Bulgaria

    Science.gov (United States)

    Popov, Nikolay; Sabic-El-Rayess, Amra

    2013-01-01

    William Russell became one of the most influential educators in the field of international and comparative education in the first half of the 20th century. In 1914, William Russell obtained his PhD from Teachers College and, within few years, became a prominent figure internationally. He traveled through Europe and taught in Japan and Siberia, as…

  12. Silver-Russell Syndrome: A Case Report

    Science.gov (United States)

    Kumar, Sunil; Jain, AP; Agrawal, Sachin; Chandran, Sindu

    2008-01-01

    A 15-year-old male boy with hemihypertrophy (left side) of the body was admitted in the hospital with the history of repeated attacks of convulsion. The patient was diagnosed as Silver-Russell syndrome on clinical ground. Silver-Russell syndrome (SRS) is a very rare genetic disorder that appears no later than early childhood. This is usually characterized by asymmetry in the size of the two halves or other parts of the body. Silver-Russell Syndrome occurs mostly in isolated cases because of sporadic genetic changes (mutations) for no apparent reason. For lack of facilities we were not able to do genetic study. PMID:18992170

  13. Defrosting of Russell Crater Dunes

    Science.gov (United States)

    2007-01-01

    These two images (at right) were acquired by the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) 39 days apart at 19:10 UTC (2:10 PM EST) on December 28, 2006 (upper right) and at 20:06 UTC (3:06 PM EST) on February 5, 2007 (lower right). These CRISM data were acquired in 544 colors covering the wavelength range from 0.36-3.92 micrometers, and show features as small as 20 meters (about 65 feet) across. Both images are false color composites of bands at 2.5, 1.5, and 1.25 micrometers, and are nearly centered at the same location, 54.875oS, 12.919oE (upper right) and 54.895oS, 12.943oE (lower right). Each image is approximately 11 kilometers (7 miles) across at its narrowest. These are part of a series of images capturing the evolution of carbon dioxide frost on the surface of the dunes in Russell Crater. Russell Crater is one of many craters in the southern highland region of Mars that contain large areas of sand dunes. The sand in these dunes has accumulated over a very long time period -- perhaps millions of years -- as wind blows over the highland terrain, picking up sand in some places and depositing in others. The topography of the craters forces the wind to blow up and over the crater rims, and the wind often isn't strong enough to keep the tiny grains suspended. This makes the sand fall to the ground and gradually pile up, and over time the surface breezes shape the sand into ripples and dunes. A similar process is at work at the Great Sand Dunes National Park and Preserve in Colorado, USA. The above left image shows a THEMIS daytime infrared mosaic of Russell Crater and the location of its (approximately) 30-kilometer wide dune field in the northeastern quadrant of the crater floor. Superposed on this view and shown enlarged at the upper right is CRISM image FRT000039DF. This CRISM image was acquired during the late Martian southern winter (solar longitude = 157.7o), and the bright blue in this false color composite indicates the presence of

  14. Alfred Russel Wallace deserves better.

    Science.gov (United States)

    Lloyd, David; Wimpenny, Julian; Venables, Alfred

    2010-09-01

    During 2009, while we were celebrating Charles Darwin and his The origin of species, sadly, little was said about the critical contribution of Alfred Russel Wallace (1823-1913) to the development of the theory of evolution. Like Darwin, he was a truly remarkable nineteenth century intellect and polymath and, according to a recent book by Roy Davies (The Darwin conspiracy: origins of a scientific crime), he has a stronger claim to the Theory of Evolution by Natural Selection than has Darwin. Here we present a critical comparison between the contributions of the two scientists. Sometimes referred to as 'The other beetle-hunter' and largely neglected for many decades, Wallace had a far greater experience of collecting and investigating animals and plants from their native habitats than had Darwin. He was furthermore much more than a pioneer biogeographer and evolutionary theorist, and also made contributions to anthropology, ethnography, geology, land reform and social issues. However, being a more modest, self-deprecating man than Darwin, and lacking the latter's establishment connections, Wallace's contribution to the theory of evolution was not given the recognition it deserved and he was undoubtedly shabbily treated at the time. It is time that Wallace's relationship with Darwin is reconsidered in preparation for 2013, the centenary of Wallace's death, and he should be recognized as at least an equal in the Wallace-Darwin theory of evolution.

  15. Ta-Tsing-Leu-Lee

    OpenAIRE

    Staunton, George Thomas

    2017-01-01

    Anastatic reprint of Ta-Tsing-Leu-Lee o Sia Leggi Fondamentali del Codice Penale della China, stampato e promulgato a Pekin coll’autorità di tutti gl’Imperatori Ta-Tsing, della presente dinastìa. Tradotto dal chinese da Giorgio Tommaso Staunton, membro della Società reale di Londra […] Versione italiana […] 3 vols. (Milano: dalla Stamperia di Giovanni Silvestri agli Scalini del Duomo n° 994, 1812), Italian translation of George Thomas Staunton, Ta Tsing Leu Lee; Being the Funda...

  16. Yang-Lee zeros of the Yang-Lee model

    Science.gov (United States)

    Mussardo, G.; Bonsignori, R.; Trombettoni, A.

    2017-12-01

    To understand the distribution of the Yang-Lee zeros in quantum integrable field theories we analyse the simplest of these systems given by the 2D Yang-Lee model. The grand-canonical partition function of this quantum field theory, as a function of the fugacity z and the inverse temperature β, can be computed in terms of the thermodynamics Bethe Ansatz based on its exact S-matrix. We extract the Yang-Lee zeros in the complex plane by using a sequence of polynomials of increasing order N in z which converges to the grand-canonical partition function. We show that these zeros are distributed along curves which are approximate circles as it is also the case of the zeros for purely free theories. There is though an important difference between the interactive theory and the free theories, for the radius of the zeros in the interactive theory goes continuously to zero in the high-temperature limit β → 0 while in the free theories it remains close to 1 even for small values of β, jumping to 0 only at β = 0 .

  17. An Interview with Arlie Russell Hochschild

    DEFF Research Database (Denmark)

    Willig, Rasmus

    2017-01-01

    This is the second of two interviews with Arlie Russell Hochschild, Professor Emerita of Sociology at the University of California, Berkeley. In her work, Hochschild explores the many ways we manage our emotions in personal life and perform emotional labor in the workplace.......This is the second of two interviews with Arlie Russell Hochschild, Professor Emerita of Sociology at the University of California, Berkeley. In her work, Hochschild explores the many ways we manage our emotions in personal life and perform emotional labor in the workplace....

  18. 21 CFR 864.8950 - Russell viper venom reagent.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Russell viper venom reagent. 864.8950 Section 864...) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Hematology Reagents § 864.8950 Russell viper venom reagent. (a) Identification. Russell viper venom reagent is a device used to determine the cause of an...

  19. Russel Nye: The Professor in Public Life.

    Science.gov (United States)

    Hungiville, Maurice

    1995-01-01

    A discussion of the influence of Russel Nye, a college English professor at Michigan State University and journalist, focuses on the values that shaped his teaching, scholarship, and writing and his defense of democratic values, especially in education. It is concluded that Nye's experience suggests that public service can be a source of personal…

  20. Pleasure, arousal, dominance: Mehrabian and Russell revisited

    NARCIS (Netherlands)

    Bakker, I.C.; van der Voordt, Theo; de Boon, J; Vink, P.

    2014-01-01

    This paper presents a discursive review of the dimensions pleasure, arousal and dominance that Mehrabian and Russell developed in 1974 to assess environmental perception, experience, and psychological responses. Since then numerous researchers applied these dimensions to assess the experience of the

  1. Autonomic dysfunction in a Jack Russell terrier

    Science.gov (United States)

    Caines, Deanne; Pinard, Chantale L.; Kruth, Stephen; Orr, Jeremy; James, Fiona

    2011-01-01

    A 4-year-old Jack Russell terrier was presented with an array of clinical signs suggestive of autonomic dysfunction. Many of the clinical signs were consistent with a diagnosis of dysautonomia; however, both chronicity and resolution of signs contradicted a diagnosis of this disease. PMID:21629424

  2. Needs assessment of school and community physical activity opportunities in rural West Virginia: the McDowell CHOICES planning effort.

    Science.gov (United States)

    Kristjansson, Alfgeir L; Elliott, Eloise; Bulger, Sean; Jones, Emily; Taliaferro, Andrea R; Neal, William

    2015-04-03

    McDowell CHOICES (Coordinated Health Opportunities Involving Communities, Environments, and Schools) Project is a county wide endeavor aimed at increasing opportunities for physical activity (PA) in McDowell County, West Virginia (WV). A comprehensive needs-assessment laid the foundation of the project. During the 6 month needs assessment, multiple sources of data were collected in two Town Hall Meetings (n = 80); a student online PA interest survey (n = 465); a PA and nutrition survey among 5(th) (10-11 years) and 8(th) graders (13-14 years) with questions adapted from the CDC's Youth Risk Behavior Surveillance Survey (n = 442, response rate = 82.2%); six semi-structured school and community focus groups (n = 44); school site visits (n = 11); and BMI screening (n = 550, response rate = 69.7%). One third of children in McDowell County meet the national PA minimum of 60 minutes daily. At least 40% of 5(th) and 8(th) graders engage in electronic screen activity for 3 hours or more every day. The prevalence of obesity in 5(th) graders is higher in McDowell County than the rest of WV (~55% vs. 47% respectively). SWOT analyses of focus group data suggest an overall interest in PA but also highlight a need for increase in structured PA opportunities. Focus group data also suggested that a central communication (e.g. internet-based) platform would be beneficial to advertise and boost participation both in current and future programs. Schools were commonly mentioned as potential facilities for public PA participation throughout the county, both with regards to access and convenience. School site visits suggest that schools need more equipment and resources for before, during, and after school programs. An overwhelming majority of participants in the McDowell CHOICES needs assessment were interested to participate in more PA programs throughout the county as well as to improve opportunities for the provision of such programs. Public schools were widely recognized as the hub

  3. A estrutura conceitual da experiência: McDowell e o debate Kant-Hegel = The conceptual structure of experience: McDowell and the Kant-Hegel debate

    Directory of Open Access Journals (Sweden)

    Lima, Erick Cavalheiros de

    2016-01-01

    Full Text Available O presente artigo pretende considerar a interpretação proposta por McDowell acerca do debate epistemológico travado entre Kant e Hegel. O fio condutor que adoto concerne à estrutura conceitual da experiência. Primeiramente, tento elucidar o sentido mais geral da recuperação de estratégias hegelianas pela filosofia analítica (1. Em segundo lugar, procuro descrever a posição mais geral adotada por McDowell à luz do debate Kant-Hegel (2. 1 e 2. 2, seu apelo ao argumento wittgensteiniano da linguagem privada (2. 3 e sua inserção no debate moderno em torno da percepção de qualidades secundárias e de cores (2. 4. Em seguida, eu tento a interpretação de alguns argumentos na Fenomenologia do Espírito seguindo indicações de McDowell (3. Finalmente, baseando-me na obra Having the World in View, procuro mostrar o sentido geral de sua interpretação alegórica da dialética do senhor e do escravo (4

  4. Pleasure, arousal, dominance: Mehrabian and Russell revisited

    OpenAIRE

    Bakker, I.C.; van der Voordt, Theo; de Boon, J; Vink, P.

    2014-01-01

    This paper presents a discursive review of the dimensions pleasure, arousal and dominance that Mehrabian and Russell developed in 1974 to assess environmental perception, experience, and psychological responses. Since then numerous researchers applied these dimensions to assess the experience of the physical environment and its perceived qualities. Although the dimensions appeared to be useful, there is a long-lasting debate going on among environmental psychologists about the interpretation ...

  5. The Earl Lee Street Art Campaign

    Science.gov (United States)

    Bubba

    2013-01-01

    This article describes a catchy phrase with more to its meaning than first view. A slogan "All the girls love Earl Lee," appears in street art around the world. Earl Lee is a lovable, handsome man who owns the fictitious Earl Lube industries. Originally intended to bring a smile to people's faces at a time when there wasn't much to smile…

  6. Characterization of Phenolic Compounds in Wine Lees

    Directory of Open Access Journals (Sweden)

    Ye Zhijing

    2018-03-01

    Full Text Available The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging. In this study, the total phenol content (TPC, total tannin content (TTC, mean degree of polymerization (mDP, and antioxidant activities of five white and eight red wine lees samples from different vinification backgrounds were determined. The results showed that vinification techniques had a significant (p < 0.05 impact on total phenol and tannin content of the samples. White wine lees had high mDP content compared with red ones. Catechin (50–62% and epicatechin contents were the predominant terminal units of polymeric proanthocyanidin extracted from examined samples. Epigallocatechin was the predominant extension unit of white wine lees, whereas epicatechin was the predominant compound in red wine marc. The ORAC (oxygen radical absorbance capacity assay was strongly correlated with the DPPH (α, α-diphenyl-β-picrylhydrazyl assay, and the results showed the strong antioxidant activities associated with red wine lees (PN > 35 mg Trolox/g FDM (PN: Pinot noir lees; FDM: Freeze-dried Material. This study indicates that tannin is one of the major phenolic compounds available in wine lees that can be useful in human and animal health applications.

  7. Tim Berners-Lee during the WSIS

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Tim Berners-Lee stands in front of the first web server at the Geneva Palexpo during the World Summit on the Information Society (WSIS) in 2003. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  8. Russell Body Gastritis: an Unusually Presentation of the Chronic Gastritis

    OpenAIRE

    CENGIZ PEKER, Betül; Secil KIRDOK, Fatma; DIZEN, Hayrettin

    2017-01-01

    Russell body gastritis is a rare form of chronic gastritis. It is characterized by the invasion of lamina propria by plasma cells that included eosinophilic cytoplasmic inclusion. In the literature, most of the cases are associated with Helicobacter pylori. Russell body gastritis and Helicobacter pylori infection are generally seen together incidentally. We report here two cases of Russell body gastritis with Helicobacter pylori infection in a 51-yr-old woman and a 39-yr-old man from Eskisehi...

  9. Characterization of Phenolic Compounds in Wine Lees.

    Science.gov (United States)

    Zhijing, Ye; Shavandi, Amin; Harrison, Roland; Bekhit, Alaa El-Din A

    2018-03-25

    The effect of vinification techniques on phenolic compounds and antioxidant activity of wine lees are poorly understood. The present study investigated the antioxidant activity of white and red wine lees generated at early fermentation and during aging. In this study, the total phenol content (TPC), total tannin content (TTC), mean degree of polymerization (mDP), and antioxidant activities of five white and eight red wine lees samples from different vinification backgrounds were determined. The results showed that vinification techniques had a significant ( p 35 mg Trolox/g FDM) (PN: Pinot noir lees; FDM: Freeze-dried Material). This study indicates that tannin is one of the major phenolic compounds available in wine lees that can be useful in human and animal health applications.

  10. The Russell Case: Academic Freedom vs. Public Hysteria.

    Science.gov (United States)

    McCarthy, Joseph M.

    This paper examines issues of academic freedom and the community's role in a review of public and legal events leading to the court's striking down of the 1940 appointment of Bertrand Russell to teach at the City College of New York. Russell was to teach three philosophy courses relating logic, mathematics, and science to philosophy. Episcopal…

  11. The Statecraft of Singapore's Lee Kuan Yew

    National Research Council Canada - National Science Library

    Toh, K

    1996-01-01

    .... The ejection of Singapore from the Federation led Lee to focus on two strategic goals: the survival of Singapore as an independent state while simultaneously pursuing nation-building under the threats of communism and internal ethnic conflicts...

  12. Higher-derivative Lee-Wick unification

    International Nuclear Information System (INIS)

    Carone, Christopher D.

    2009-01-01

    We consider gauge coupling unification in Lee-Wick extensions of the Standard Model that include higher-derivative quadratic terms beyond the minimally required set. We determine how the beta functions are modified when some Standard Model particles have two Lee-Wick partners. We show that gauge coupling unification can be achieved in such models without requiring the introduction of additional fields in the higher-derivative theory and we comment on possible ultraviolet completions.

  13. Alfred Russel Wallace's world of final causes.

    Science.gov (United States)

    Smith, Charles H

    2013-12-01

    Alfred Russel Wallace (1823-1913) is an important figure in the history of science, but there remain many questions about the nature of his world view, and how it developed. Here, Wallace's appreciation of the role of final causes in evolution is linked to some of its probable origins, with an emphasis on the influence of Alexander von Humboldt (1769-1859). The question is then asked whether a final causes-based scientific agenda might be possible, and answered by drawing attention to two current efforts in that direction by Adrian Bejan, and by the author. A sketch of the latter approach, adapted from Spinozian thinking, is given, with an empirical example involving drainage basin morphology that suggests structural influences of a final causes sort.

  14. Use of Awamori-pressed Lees and Tofu Lees as Feed Ingredients for Growing Female Goats

    Directory of Open Access Journals (Sweden)

    Itsuki Nagamine

    2012-12-01

    Full Text Available Okinawan Awamori is produced by fermenting steamed indica rice with black mold, yeast, and water. Awamori-pressed lees is a by-product of the Awamori production process. Tofu lees is a by-product of the Tofu production process. This research consisted of two experiments conducted to elucidate whether or not dried Awamori-pressed lees and Tofu lees can be used as a mixed feed ingredient for raising female goats. In experiment 1, digestion trials were conducted to ascertain the nutritive values of dried Awamori-pressed lees and dried Tofu lees for goats. The digestible crude protein (DCP and total digestible nutrients (TDN contents of dried Awamori-pressed lees and Tofu lees were 22.5%, 22.5% (DCP, and 87.2%, 94.4% (TDN respectively. In experiment 2, 18 female goats (Japanese Saanen×Nubian, three months old, body weight 15.4±0.53 kg were divided into three groups of six animals (control feed group (CFG, Awamori-pressed lees mixed feed group (AMFG, Tofu lees mixed feed group (TMFG. The CFG control used feed containing 20% soybean meal as the main protein source, while the AMFG and TMFG treatments used feed mixed with 20% dried Awamori-pressed lees or dried Tofu lees. The groups were fed mixed feed (volume to provide 100 g/d increase in body weight twice a day (10:00, 16:00. The klein grass hay and water was given ad libitum. The hay intake was measured at 08:00 and 16:00. Body weight and size measurements were taken once a month. At the end of the experiment, a blood sample was drawn from the jugular vein of each animal. The DCP and TDN intakes in AMFG and TMFG showed no significant difference to the CFG. Cumulative measurements of growth in body weight, withers height, chest depth, chest girth, and hip width over the 10 mo period in the AMFG and TMFG were similar to the CFG. By contrast, cumulative growth in body length and hip height in the AMFG and TMFG tended to be larger than the CFG. Cumulative growth in chest width in the AMFG was

  15. Tom Russell: "Õpetajakoolitust tuleks alustada praktikast" / Liisa Lumiste

    Index Scriptorium Estoniae

    Lumiste, Liisa

    2013-01-01

    Eduko programmi raames Tallinna Ülikoolis toimunud avalikul loengul rääkis Kanada kasvatusteadlane Tom Russell praktika tähtsusest õpetajakoolituses ja viis läbi meistriklassi õpetajakoolituse õppejõududele

  16. Diagnosis and management of Silver-Russell syndrome

    DEFF Research Database (Denmark)

    Wakeling, Emma L; Brioude, Frédéric; Lokulo-Sodipe, Oluwakemi

    2017-01-01

    This Consensus Statement summarizes recommendations for clinical diagnosis, investigation and management of patients with Silver-Russell syndrome (SRS), an imprinting disorder that causes prenatal and postnatal growth retardation. Considerable overlap exists between the care of individuals born s...

  17. Epigenoty-pephenotype correlations in Silver-Russell syndrome

    NARCIS (Netherlands)

    Wakeling, E. L.; Abu Amero, S.; Alders, M.; Bliek, J.; Forsythe, E.; Kumar, S.; Lim, D. H.; MacDonald, F.; Mackay, D. J.; Maher, E. R.; Moore, G. E.; Poole, R. L.; Price, S. M.; Tangeraas, T.; Turner, C. L. S.; Van Haelst, M. M.; Willoughby, C.; Temple, I. K.; Cobben, J. M.

    2010-01-01

    Background Silver Russell syndrome (SRS) is characterised by intrauterine growth restriction, poor postnatal growth, relative macrocephaly, triangular face and asymmetry. Maternal uniparental disomy (mUPD) of chromosome 7 and hypomethylation of the imprinting control region (ICR) 1 on chromosome

  18. Bertrand Russell Tribunal considers population control.

    Science.gov (United States)

    Mass, B

    1974-01-01

    A summary of a "scientific report" on the development and implementation of population control in Latin America is presented. The report is to be presented at the Bertrand Russell Tribunal 2, concerned with repression in Latin America, in Brussels, Belgium, in January 1975. Hearings from the 1966-1968 U.S. Senate subcommittee on Foreign Aid Expenditures are cited to show evidence of American economic and military interests using theories of population control as a solution to deteriorating material conditions in Latin America. Explosive populations are also regarded as causes of political instability. The report further cites the "widespread use of coercive and misleading birth control propaganda" which distorts cultural and economic factors determining personal choices available to Latin American families. High birthrates are pictured as a major cause of poverty, slow economic growth, and scarcity of raw materials. Evidence of dangerous clinical testing of birth control products in Latin America, beginning in the 1930s in Puerto Rico, is presented. The questionable population policies of such institutions as the World Bank and the Rockefeller Foundation are also discussed.

  19. On the linear programming bound for linear Lee codes.

    Science.gov (United States)

    Astola, Helena; Tabus, Ioan

    2016-01-01

    Based on an invariance-type property of the Lee-compositions of a linear Lee code, additional equality constraints can be introduced to the linear programming problem of linear Lee codes. In this paper, we formulate this property in terms of an action of the multiplicative group of the field [Formula: see text] on the set of Lee-compositions. We show some useful properties of certain sums of Lee-numbers, which are the eigenvalues of the Lee association scheme, appearing in the linear programming problem of linear Lee codes. Using the additional equality constraints, we formulate the linear programming problem of linear Lee codes in a very compact form, leading to a fast execution, which allows to efficiently compute the bounds for large parameter values of the linear codes.

  20. Síndrome de Silver-Russell: relato de caso Silver-Russell Syndrome: case report

    Directory of Open Access Journals (Sweden)

    Natalia Freitas Rossi

    2006-12-01

    Full Text Available OBJETIVO: descrever o fenótipo da síndrome de Silver-Russell (SSR e apresentar um caso diagnosticado com esta afecção genética, abordando aspectos genéticos, psicológicos e fonoaudiológicos. MÉTODOS: trata-se de relato de caso de uma criança do gênero feminino, sete anos e onze meses, portadora da síndrome de Silver-Russel. Foram realizadas avaliação genética médica e molecular, avaliação psicológica, avaliação fonoaudiológica e aplicação de testes complementares. RESULTADOS: a análise molecular da região 7p11 excluiu a dissomia uniparental para este caso. No exame físico foram constatados os principais sinais clínicos da SSR que incluiu retardo no crescimento de origem pré-natal, fácies típica, assimetrias ósseas e clinodactilia do 5º dedo. A avaliação cognitiva e fonoaudiológica mostraram deficiência mental, distúrbio de linguagem oral e comprometimento das funções orais. CONCLUSÃO: o estudo deste caso possibilitou a divulgação do fenótipo da SSR com suas manifestações físicas, cognitivas e fonoaudiológicas. Embora o teste molecular não tenha confirmado um dos possíveis mecanismos etiológicos da síndrome, a avaliação genética médica constatou a presença dos principais sinais clínicos que foram correlacionados à literatura. A avaliação psicológica e fonoaudiológica apontaram para comprometimento cognitivo e de comunicação, funções orais , sugerindo que importantes alterações fonoaudiológicas podem fazer parte do fenótipo desta síndrome, ainda pouco difundida para fonoaudiólogos.PURPOSE: to describe Silver-Russell syndrome (SRS phenotype and report a case with this condition, concerning genetics, psychological and speech/language and oral function evaluation. METHODS: we will submit the case of a girl, seven years and eleven months with Silver-Russell syndrome. Medical genetic evaluation, molecular test, psychological and speech/language evaluation was done. Complementary

  1. Statistical study of some Lee galaxy groups

    Science.gov (United States)

    Mohamed, Sabry A.; Fouad, Ahmed M.

    2017-12-01

    Compact groups of galaxies are systems of small number of galaxies close to each other. They are a good laboratory to study galaxy properties, such as structure, morphology and evolution which are affected by the environment and galaxy interactions. We applied the tree clustering technique (the Euclidean separation distance coefficients) to test the physical reality of groups and used certain criteria (Sabry et al., 2009) depending on the physical attributes of the galaxies. The sample of the data is the quintets groups of Lee compact groups of galaxies (Lee et al., 2004). It is based on a modified version of Hickson's criteria (Hickson, 1982). The results reveal the membership of each galaxy and how it is related to its group. The tables of groups and their members are included. Our results indicates that 12 Groups are real groups with real members while 18 Groups have one galaxy that has attribute discordant and should be discarded from its group.

  2. Instability of the Lee-Wick bounce

    International Nuclear Information System (INIS)

    Karouby, Johanna; Brandenberger, Robert; Qiu, Taotao

    2011-01-01

    It was recently realized [Y. F. Cai, T. t. Qiu, R. Brandenberger, and X. m. Zhang, Phys. Rev. D 80, 023511 (2009).] that a model constructed from a Lee-Wick type scalar field theory yields, at the level of homogeneous and isotropic background cosmology, a bouncing cosmology. However, bouncing cosmologies induced by pressureless matter are in general unstable to the addition of relativistic matter (i.e. radiation). Here we study the possibility of obtaining a bouncing cosmology if we add radiation coupled to the Lee-Wick scalar field. This coupling in principle would allow the energy to flow from radiation to matter, thus providing a drain for the radiation energy. However, we find that it takes an extremely unlikely fine-tuning of the initial phases of the field configurations for a sufficient amount of radiative energy to flow into matter. For general initial conditions, the evolution leads to a singularity rather than a smooth bounce.

  3. Russell body gastritis: case report Gastrite com corpúsculos de Russell: relato de caso

    Directory of Open Access Journals (Sweden)

    Eduardo Cambruzzi

    2012-02-01

    Full Text Available Russell body gastritis (RBG, which can be associated with Helicobacter pylori (HP infection, is a recently acknowledged lesion characterized by the presence of eosinophilic intracytoplasmic inclusions in plasmacytes. Herein the authors discuss the morphological aspects of a case of RBG in a male patient with clinical complaint of epigastric pain. Upper endoscopy revealed areas of erythema/edema in the antrum. As far as microscopy is concerned, a mononuclear inflammatory infiltrate was identified on the lamina propria, with plasma cells containing Schiff acid periodic (PAS positive eosinophilic intracytoplasmic globules, which showed positive immunostaining for CD79a, CD138, and kappa/lambda light chains. HP was identified by Giemsa stains.A gastrite com corpúsculos de Russell (RBG, que pode estar associada à infecção por Helicobacter pylori (HP, é uma lesão recentemente reconhecida que se caracteriza pela presença de inclusões eosinofílicas intracitoplasmáticas em plasmócitos. Neste relato, os autores discutem os aspectos morfológicos de um caso de RBG em um paciente masculino com queixa clínica de dor epigástrica. A endoscopia revelou áreas de eritema/edema no antro. À microscopia, um infiltrado inflamatório mononuclear foi identificado na lâmina própria, com plasmócitos exibindo glóbulos eosinofílicos intracitoplasmáticos ácido periódico de Schiff (PAS positivos, que apresentaram imunoexpressão positiva para CD79a,CD138 e cadeias leves kappa/lambda. HP foi identificado na coloração de Giemsa.

  4. Lipid composition of lees from Sherry wine.

    Science.gov (United States)

    Gómez, Maria Ester; Igartuburu, José M; Pando, Enrique; Luis, Francisco Rodríguez; Mourente, Gabriel

    2004-07-28

    In this paper, we describe the study and characterization of the lipids from lees of Sherry wine, one of the main byproducts from the wine-making industry in the Jerez/Xeres/Sherry denomination of the origin zone in Jerez de la Frontera, Spain. The lipid content, extractability, classification, fatty acid composition, and its main chemical characteristics have been determined in order to evaluate their potential use as a food or food additive. Copyright 2004 American Chemical Society

  5. Statistical study of some Lee galaxy groups

    Directory of Open Access Journals (Sweden)

    Sabry A. Mohamed

    2017-12-01

    Full Text Available Compact groups of galaxies are systems of small number of galaxies close to each other. They are a good laboratory to study galaxy properties, such as structure, morphology and evolution which are affected by the environment and galaxy interactions. We applied the tree clustering technique (the Euclidean separation distance coefficients to test the physical reality of groups and used certain criteria (Sabry et al., 2009 depending on the physical attributes of the galaxies. The sample of the data is the quintets groups of Lee compact groups of galaxies (Lee et al., 2004. It is based on a modified version of Hickson’s criteria (Hickson, 1982. The results reveal the membership of each galaxy and how it is related to its group. The tables of groups and their members are included.Our results indicates that 12 Groups are real groups with real members while 18 Groups have one galaxy that has attribute discordant and should be discarded from its group. Keywords: Galaxies, Cluster analysis, Galaxy groups, Lee galaxy groups

  6. Myotonia congenita in a Jack Russell terrier : clinical communication

    Directory of Open Access Journals (Sweden)

    R.G. Lobetti

    2009-05-01

    Full Text Available A 4-month-old male Jack Russell terrier was evaluated for non-painful muscle spasms and collapse associated with exercise and activity. Clinical examination revealed well-defined, non-painful hypertrophic muscles of the fore and hind limbs and exercise and excitement induced hindquarter bunny-hopping gait, which improved with activity but worsened with resting and with any sudden changes in direction of movement. Neurological examination and routine laboratory testing showed no abnormalities. DNA analysis for myotonia congenita showed the dog to have a gene mutation in the chloride ion channel, diagnostic for myotonia congenita, which has not been reported in the Jack Russell terrier breed.

  7. Obituary: Russell Makidon (1971-2009)

    Science.gov (United States)

    Sivaramakrishnan, Anand

    2009-12-01

    Russell Benjamin Makidon died at the age of 38 in Baltimore on June 22, 2009. Complications following surgery to remove a tumor cut his life tragically short. Russ was a Mission Systems Scientist at the Space Telescope Science Institute (STScI), which he joined straight out of graduate school in 1997. He brought both the force of his intellect and his superb people skills to STScI, where he served the Institute and the broader community with extraordinary effectiveness. Russ was pivotal in helping to develop the wavefront sensing and control system of the James Webb Space Telescope (JWST). He was also a member of the NSF Center for Adaptive Optics at Lick Observatory. Born to Cathy Ann and Peter Makidon, a worker at General Motors, on January 22, 1971, in Bay City, Michigan, Russ was an only child. He was raised by his mother, in Florida, and her parents, in Munger, Michigan. He is survived by his mother, his grandfather Benjamin Franklin Histed, and his father. In addition to his interest in science, Russ was a talented artist and his sketches had appeared in statewide and national competitions. Turning down a scholarship at the Savannah College of Art and Design, he studied physics and astronomy at the University of Michigan, followed by a Masters under Stephen Strom at the University of Massachusetts. He measured pre-main sequence stellar rotation in NGC 2264 and other OB associations, providing insight on the role that circumstellar disks play in setting stellar angular momentum in young stellar clusters and associations. This work, and his extraordinary skills in facilitating scientific exchange, led to his co-investigatorship on the Hubble Space Telescope (HST) Orion Treasury Project. Russ advanced the understanding of high contrast imaging, especially the relation between the properties of a wavefront control or adaptive optics systems and the physics of coronagraphic imaging. He developed a practical understanding of coronagraphy, performing timely and

  8. 76 FR 20388 - Russell Investment Company, et al.; Notice of Application

    Science.gov (United States)

    2011-04-12

    ... the Act to invest in certain financial instruments. Applicants: Russell Investment Company and Russell... pursuant to the advisory agreement of any investment company in which the Applicant Fund may invest... COMMISSION Russell Investment Company, et al.; Notice of Application April 6, 2011. AGENCY: Securities and...

  9. Telling Lewis Hine's Story: Russell Freedman's "Kids at Work."

    Science.gov (United States)

    Zarnowski, Myra

    In "Kids at Work," Russell Freedman explores the world of child labor during the years 1908-1918 when Lewis Hine, "teacher-crusader," worked as an investigative photographer for the National Child Labor Committee (NCLC). Hine's writing and the photos he gathered from across the country revealed a "shocking reality that…

  10. Epigenotype-phenotype correlations in Silver-Russell syndrome

    NARCIS (Netherlands)

    Wakeling, E. L.; Amero, S. Abu; Alders, M.; Bliek, J.; Forsythe, E.; Kumar, S.; Lim, D. H.; Macdonald, F.; Mackay, D. J.; Maher, E. R.; Moore, G. E.; Poole, R. L.; Price, S. M.; Tangeraas, T.; Turner, C. L. S.; van Haelst, M. M.; Willoughby, C.; Temple, I. K.; Cobben, J. M.

    2010-01-01

    Silver-Russell syndrome (SRS) is characterised by intrauterine growth restriction, poor postnatal growth, relative macrocephaly, triangular face and asymmetry. Maternal uniparental disomy (mUPD) of chromosome 7 and hypomethylation of the imprinting control region (ICR) 1 on chromosome 11p15 are

  11. Is Russell's vicious circle principle false or meaningless?

    NARCIS (Netherlands)

    Fleischhacker, L.E.

    1979-01-01

    P. Vardy asserts the thesis that the vicious circle principle has the same structure as Russell's paradox. But structure is not the thing itself. It is the thing objectivated from the wiewpoint of a mathematician. So this structure can be expressed in a mathematical formalism, e. g. the Λ-calculus.

  12. A case of Silver–Russell syndrome (SRS): multiple pituitary ...

    Indian Academy of Sciences (India)

    and adolescence: summary statement of the GH research society. J. Clin. Endocrinol. Metab. 85, 3990–3993. Gicquel C., Rossignol S., Cabrol S., Houang M., Steunou V., Barbu. V. et al. 2005 Epimutation of the telomeric imprinting centre region on chromosome 11p15 in Silver-Russell syndrome. Nat. Genet. 37, 1003–1007 ...

  13. Negative effect of discharging vinification lees on soils.

    Science.gov (United States)

    Moldes, Ana B; Vázquez, Manuel; Domínguez, José M; Díaz-Fierros, Francisco; Barral, María T

    2008-09-01

    In this work, vinification lees from Galicia (Spain) were chemically analysed and compared with the composition of vinification lees from other regions and residues. Moreover, vinification lees were submitted to biological test employing cress, spring barley and ryegrass seeds. The evaluated vinification lees were rich in nutrients that are essential for plants, like P (2,520 mg kg(-1)), K (36,738 mg kg(-1)) and Mg (462 mg kg(-1)), but have low pH (3.9) and high C/N ratio. However, when vinification lees were submitted to biological tests, no germination was observed for garden cress and ryegrass seeds and almost no germination for spring barley seeds, showing the negative effect of discharging lees on crop fields.

  14. Russell bodies in a skin biopsy: a case report

    Directory of Open Access Journals (Sweden)

    Verheij Joanne

    2009-11-01

    Full Text Available Abstract Introduction The presence of eosinophilic bodies in a skin biopsy can be found in a variety of situations and this may present a challenge to the pathologist. The differential diagnosis of these eosinophilic structures include microorganisms such as histoplasmosis or cryptococcosis, fungi, Michaelis-Gutmann bodies, deposits of amyloid or immunoglobulins, colloid bodies or elastic bodies. Case presentation During a routine examination of a skin biopsy with actinic keratosis taken from the cheek of a 61-year-old man, clusters of eosinophilic bodies were seen within an inflammatory infiltrate in the dermis, both intracytoplasmic and extracellular. Using additional immunohistochemical staining, these structures were identified as polyclonal Russell bodies. Conclusion The differential diagnosis of intracytoplasmic eosinophilic structures in a skin biopsy includes Russell bodies, an uncommon finding that may be associated with chronic inflammatory conditions.

  15. The Church in the Thought of Charles Taze Russell

    Science.gov (United States)

    1990-07-01

    and putting into force of the New Covenant was completed by the fiftieth day following the crucifixion oIf Jesus . Thus, the death of Christ, by meeting...heirs with Jesus in what Russell called the "New Creation." In a sense, there was a heavenly organization that had continued since apostolic times...specifically with reference to Jesus and his saving work. 5 3penton, Apocalypse Delayed, pp. 35ff. 34 The doctrine of the New Covenant specifically

  16. Alfred Russel Wallace and the Antivaccination Movement in Victorian England

    OpenAIRE

    Weber, Thomas P.

    2010-01-01

    Alfred Russel Wallace, eminent naturalist and codiscoverer of the principle of natural selection, was a major participant in the antivaccination campaigns in late 19th-century England. Wallace combined social reformism and quantitative arguments to undermine the claims of provaccinationists and had a major impact on the debate. A brief account of Wallace’s background, his role in the campaign, and a summary of his quantitative arguments leads to the conclusion that it is unwarranted to portra...

  17. Retrospective: Ivy Lee and the German Dye Trust.

    Science.gov (United States)

    Hainsworth, Brad E.

    1987-01-01

    Examines the relationship between public relations trailblazer Ivy Lee and the German Dye Trust, which became an agent for the policies of Adolf Hitler. Discusses how Lee's efforts to use this relationship to persuade his contacts to influence the Nazi leadership failed because of his formal connection with this group. (JD)

  18. Tim Berners-Lee and Kofi Annan during the WSIS

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  19. Tim Berners-Lee and Kofi Annan during the WSIS

    CERN Document Server

    Patrice Loïez

    2003-01-01

    During the 2003 World Summit on the Information Society (WSIS) at Geneva Palexpo, Tim Berners-Lee, W3C's director (World Wide Web consortium) was introduced to Kofi Annan, Secretary General of the United Nations. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  20. Complete synchronization of two Chen-Lee systems

    International Nuclear Information System (INIS)

    Sheu, L-J; Chen, J-H; Chen, H-K; Tam, L-M; Lao, S-K; Chen, W-C; Lin, K-T

    2008-01-01

    This study demonstrates that complete synchronization of two Chen-Lee chaotic systems can be easily achieved. The upper bound of the Chen-Lee chaotic system is estimated numerically. A controller is designed to synchronize two chaotic systems. Sufficient conditions for synchronization are obtained using Lyapunov's direct method. Two numerical examples are presented to verify the proposed synchronization approach

  1. Web Inventor Berners-Lee starts a Blog

    CERN Document Server

    Olson, Parmy

    2005-01-01

    Berners-Lee created what is known today as the World Wide Web. Now, just in time for the Web's 15th anniversary and after taking his proverbial stroll around the global dwelling of cyberspace, Berners-Lee is chatting with the rest of us about what he thinks with a blog

  2. Tim Berners-Lee receives the Millennium Technology Prize

    CERN Multimedia

    2004-01-01

    On 15 April, for his invention of the Web, Tim Berners-Lee was awarded the first ever Millennium Technology Prize by the Finnish Technology Award Foundation, which recognises technological innovations of lasting benefit to society. "Tim Berners-Lee's invention perfectly encapsulates the spirit of the Prize. The Web is encouraging new types of social networks, contributing to transparency and democracy, and opening up new avenues for information management and business development," underlined Pekka Tarjanne, chairman of the jury and former Secretary-General of the International Telecommunication Union (ITU). Tim Berners-Lee is congratulated by Jukka Valtasaari, Finland's Ambassador to the United States. Tim Berners-Lee created the first server, browser and editor, the HTML code, the URL address and the HTTP transmission protocol at CERN in 1990. CERN released the Web into the public domain in 1993. Tim Berners-Lee is currently head of the World Wide Web Consortium, managed by ERCIM (Europe...

  3. Thermodynamics of the Lee-Wick partners: An alternative approach

    International Nuclear Information System (INIS)

    Bhattacharya, Kaushik; Das, Suratna

    2011-01-01

    It was pointed out some time ago that there can be two variations in which the divergences of a quantum field theory can be tamed using the ideas presented by Lee and Wick. In one variation the Lee-Wick partners of the normal fields live in an indefinite metric Hilbert space but have positive energy and in the other variation the Lee-Wick partners can live in a normal Hilbert space but carry negative energy. Quantum mechanically the two variations mainly differ in the way the fields are quantized. In this article the second variation of Lee and Wick's idea is discussed. Using statistical mechanical methods the energy density, pressure and entropy density of the negative energy Lee-Wick fields have been calculated. The results exactly match with the thermodynamic results of the conventional, positive energy Lee-Wick fields. The result sheds some light on the second variation of Lee-Wick's idea. The result seems to say that the thermodynamics of the theories do not care about the way they are quantized.

  4. Bertrand Russell: pacifismo político relativo

    Directory of Open Access Journals (Sweden)

    Francisco A. Laca-Arocena

    2011-01-01

    Full Text Available Siguiendo la biografía de Bertrand Russell (1872-1970, lógico matemático, filósofo, premio Nobel de Literatura 1950 y militante pacifista a lo largo de gran parte del conflictivo siglo XX, se analiza el doble conflicto que afronta un pacifista: de desobediencia civil a un gobierno que ha declarado una guerra y de relativa marginación social con una opinión pública cuando ésta es mayoritariamente favorable a esa guerra. Tras un breve análisis del pacifismo contrastándolo con una doble tradición en el pensamiento político anglosajón, el utilitarismo y la teoría del contrato social, se incide en la distinción personal de Russell entre guerras ¿de prestigio¿ y ¿de valores¿. Fue pacifista en la Primera Guerra Mundial considerándola una guerra de prestigio, pero fue partidario de oponerse al nazismo en la Segunda Guerra entendiendo que se trataba de un combate de valores. Volvería a un activismo pacifista en su oposición a la guerra de Vietnam. Estas diferentes posiciones ante la guerra en relación con lo que en cada caso esté en juego, se conoce como ¿pacifismo político relativo¿, cuyo representante más genuino fue el propio Russell.

  5. Constraints on the Lee-Wick Higgs sector

    International Nuclear Information System (INIS)

    Carone, Christopher D.; Primulando, Reinard

    2009-01-01

    Lee-Wick partners to the standard model Higgs doublet may appear at a mass scale that is significantly lower than that of the remaining Lee-Wick partner states. The relevant effective theory is a two-Higgs doublet model in which one doublet has wrong-sign kinetic and mass terms. We determine bounds on this effective theory, including those from neutral B-meson mixing, b→X s γ, and Z→bb. The results differ from those of conventional two-Higgs doublet models and lead to meaningful constraints on the Lee-Wick Higgs sector.

  6. FILSAFAT ANALITIK Kritik Epistemologi Ide Analitik Logis Bertrand Russell

    Directory of Open Access Journals (Sweden)

    Muhmidayeli Muhmidayeli

    2016-03-01

    Full Text Available Abstract:Each logical statement reflected in the way expressed in a logical language. If a statement is expressed by a language that one would then have it wrong, therefore, necessary test of logical forms that fit with the empirical facts. In short every statement must be understood by returning to the real meaning or context. Russell offers a translation grammatically any statement that may seem misleading to the appropriate forms and logical. Bertrand Russell described his philosophy asan area of human thought that was between theology on the one hand and science on the other side. Philosophy can be said astheology, due to the nature and character of philosophy which also contains a world speculations about the definitive knowledge, but it can notbe ascertained. On the other hand, itcan be said as science, because the working procedures of philosophy that is moreleads and functioning sense like science knowledge (science. Anydogma, because it transcends knowledge certainly, including in the sphere of theology. In between there is this no man's land area that is prone to both theology and science issues. Abstrak: Setiap penyataan logis tercermin dari cara mengungkapkannya dalam bahasa logis. Jika suatu pernyataan diungkap dengan bahasa yang salah maka akan memiliki maka yang salah, oleh karena itu, diperlukan uji bentuk-bentuk logis yang cocok dengan dengan fakta empiris. Pendeknya setiap pernyataan mesti dipahami dengan mengembalikannya pada makna riil atau kontekstual. Russell menawarkan pener¬jemahan secara gramatikal setiap pernyataan yang mungkin saja tampak me¬nyesat¬¬kan ke dalam bentuk-bentuk yang tepat dan logis. Bertrand Russell menggambarkan filsafat sebagai suatu wilayah pemikiran manusia yang berada antara teologi di satu sisi dan ilmu pengetahuan di sisi lainnya. Filsafat dapat dikatakan seperti teologi, karena sifat dan watak filsafat yang juga bersikan dunia spekulasi-spekulasi tentang pengetahun yang pasti namun ia tidak

  7. Alfred Russell Wallace and the evolution of the human mind.

    Science.gov (United States)

    Gross, Charles

    2010-10-01

    Today the fame of Alfred Russell Wallace is as the independent codiscoverer with Charles Darwin of the origin of species by natural selection. Although they were on very amiable terms all their lives, 11 years after announcing their discovery, Wallace and Darwin had a major disagreement on the evolution of human cognition. The author considers how this divergence and other disagreements, particularly on the role of instinct, are related to the differences in their class backgrounds, education, experience with non-European cultures, and views on socialism, phrenology, mesmerism, and spiritualism.

  8. Destructive Cholangitis in an Adult Jack Russell Terrier

    Directory of Open Access Journals (Sweden)

    Atsushi Kodama

    2012-01-01

    Full Text Available A 4-year-old female Jack Russell terrier dog exhibited vomiting and severe jaundice of the visible mucous membranes and skin. Ultrasonography revealed diffuse areas of high echogenicity and focal areas of low echogenicity in the left lobe of the liver. On macroscopic observation of the biopsied liver specimen, many scattered irregularly shaped red spots were observed on the liver surface and on the cut surface. Histopathologically, there was loss of the interlobular bile duct and cholangitis accompanied by infiltration of pigment-laden macrophages in the Glisson’s capsule. Therefore, in the present case the dog was diagnosed with destructive cholangitis.

  9. Alfred Russel Wallace and the antivaccination movement in Victorian England.

    Science.gov (United States)

    Weber, Thomas P

    2010-04-01

    Alfred Russel Wallace, eminent naturalist and codiscoverer of the principle of natural selection, was a major participant in the antivaccination campaigns in late 19th-century England. Wallace combined social reformism and quantitative arguments to undermine the claims of provaccinationists and had a major impact on the debate. A brief account of Wallace's background, his role in the campaign, and a summary of his quantitative arguments leads to the conclusion that it is unwarranted to portray Victorian antivaccination campaigners in general as irrational and antiscience. Public health policy can benefit from history, but the proper context of the evidence used should always be kept in mind.

  10. Bertrand Russell: pacifismo político relativo

    OpenAIRE

    Francisco A. Laca-Arocena

    2011-01-01

    Siguiendo la biografía de Bertrand Russell (1872-1970), lógico matemático, filósofo, premio Nobel de Literatura 1950 y militante pacifista a lo largo de gran parte del conflictivo siglo XX, se analiza el doble conflicto que afronta un pacifista: de desobediencia civil a un gobierno que ha declarado una guerra y de relativa marginación social con una opinión pública cuando ésta es mayoritariamente favorable a esa guerra. Tras un breve análisis del pacifismo contrastándolo con una doble tradici...

  11. Humans, Animals and the World We Inhabit--On and beyond the Symposium "Second Nature, 'Bildung' and McDowell: David Bakhurst's 'The Formation of Reason'"

    Science.gov (United States)

    Misawa, Koichiro

    2017-01-01

    David Bakhurst's 2011 book "The Formation of Reason" explores the philosophy of John McDowell in general and the Aristotelian notion of second nature more specifically, topics to which philosophers of education have not yet given adequate attention. The book's widespread appeal led to the symposium "Second Nature, Bildung and…

  12. General Robert E. Lee -- Brightest Star in the South

    National Research Council Canada - National Science Library

    Dalton, Kent B

    2006-01-01

    .... Lee's distinctive application of operational art and leadership as the commander of the Army of Northern Virginia, we can discern many lessons which are still pertinent to our commanders at the operational level today...

  13. The Statecraft of Lee Kuan Yew, Visionary and Opportunist

    National Research Council Canada - National Science Library

    Thomas, David

    1996-01-01

    ...." "Not so," replied the passenger, Lee Kuan Yew, "Singapore intends to continue to ride along as part of the federation created with Malaysia, Sarawak, and Sabah -- we have no plans for getting off...

  14. Nobel laureate T.D. Lee at CERN

    CERN Multimedia

    2007-01-01

    On 30 August, Professor T.D. Lee, who received the Nobel Prize for Physics in 1957, gave a seminar at CERN on symmetry and asymmetry in electroweak interactions, 50 years after the discovery of the non-conservation of parity. In 1956, Tsung-Dao Lee postulated with Chen Ning Yang that parity is not conserved in weak interactions, and suggested several experiments to demonstrate this. The following year, an experiment led by Chien-Shiung Wu proved this prediction and, soon after, T.D. Lee and Chen Ning Yang were awarded the Nobel Prize for Physics. Still very active at over 80 years of age, T.D. Lee pursues his theory work to this day.

  15. Woods and Russell, Hill, and the emergence of medical statistics.

    Science.gov (United States)

    Farewell, Vern; Johnson, Tony

    2010-06-30

    In 1937, Austin Bradford Hill wrote Principles of Medical Statistics (Lancet: London, 1937) that became renowned throughout the world and is widely associated with the birth of modern medical statistics. Some 6 years earlier Hilda Mary Woods and William Thomas Russell, colleagues of Hill at the London School of Hygiene and Tropical Medicine, wrote a similar book An Introduction to Medical Statistics (PS King and Son: London, 1931) that is little known today. We trace the origins of these two books from the foundations of early demography and vital statistics, and make a detailed examination of some of their chapters. It is clear that these texts mark a watershed in the history of medical statistics that demarcates the vital statistics of the nineteenth and early twentieth centuries from the modern discipline. Moreover, we consider that the book by Woods and Russell is of some importance in the development of medical statistics and we describe and acknowledge their place in the history of this discipline. (c) 2010 John Wiley & Sons, Ltd.

  16. Russell Crowe maailma tipust maailma äärele / Timo Diener

    Index Scriptorium Estoniae

    Diener, Timo

    2003-01-01

    Näitleja Russell Crowe ja tema suhe oma rolliga seiklusfilmis "Kapten ja komandör : retk maailma äärele" ("Master and Commander : The Far Side of the World") : stsenarist Patrick O'Briani romaanide järgi ja režissöör Peter Weir : peaosas Russell Crowe : Ameerika Ühendriigid 2003

  17. 75 FR 67095 - Charles M. Russell National Wildlife Refuge and UL Bend National Wildlife Refuge, Montana

    Science.gov (United States)

    2010-11-01

    ... Fish and Wildlife Service Charles M. Russell National Wildlife Refuge and UL Bend National Wildlife Refuge, Montana AGENCY: Fish and Wildlife Service, Interior (DOI). ACTION: Notice; extension of comment... Charles M. Russell and UL Bend National Wildlife Refuges (NWRs, Refuges) in Montana for public review and...

  18. Semi-analytical formulas for the Hertzsprung-Russell diagram

    Directory of Open Access Journals (Sweden)

    Zaninetti L.

    2008-01-01

    Full Text Available The absolute visual magnitude as function of the observed color (B-V, also named Hertzsprung-Russell diagram, can be described through five equations; that when calibrated stars are available means eight constants. The developed framework allows to deduce the remaining physical parameters, mass, radius and luminosity. This new technique is applied to the first 10 pc, the first 50 pc, the Hyades and to the determination of the distance of a cluster. The case of the white dwarfs is analyzed assuming the absence of calibrated data: our equation produces a smaller χ2 with respect to the standard color-magnitude calibration when applied to the Villanova Catalog of Spectroscopically Identified White Dwarfs. The theoretical basis of the formulas for the colors and the bolometric correction of the stars is clarified by a Taylor expansion in the temperature of the Planck distribution.

  19. Democracia, poder y minorías en Bertrand Russell

    Directory of Open Access Journals (Sweden)

    Álvaro Carvajal Villaplana

    2013-11-01

    Full Text Available En este artículo se hace un análisis de la noción de democracia como doma del poder del filósofo analítico Bertrand Russell, idea que aparece en su libro Power (1938. A este concepto se lo vincula con la defensa de las minorías, y en este artículo esta idea se extiende a la defensa de las minorías sexuales. Asimismo, se hace una correlación con el pensamiento de Leibniz de que debe haber un control ético del poder de los gobernantes y con la idea de la democracia vacía de Jacques Ranciére.

  20. A historical legacy: Henry-Russell Hitchcock and early Modernism

    Directory of Open Access Journals (Sweden)

    Macarena de la Vega

    2015-07-01

    Full Text Available On the occasion of the publication of Modern Architecture: Romanticism and Reintegration’s first Spanish edition. This essay aims to discuss the impact of Henry- Russell Hitchcock’s book –published in 1929– on the history of architecture. In spite of being the first history of modern architecture written in English, Modern Architecture fell into oblivion due to the success of Hitchcock’s subsequent book, coauthored with Philip Johnson: The International Style: Architecture since 1922. Discussing the critical approaches to the text –from the first book reviews to the latest historiographical studies– brings to light Hitchcock’s contribution to the historiography of modern architecture.

  1. Radiation bounce from the Lee-Wick construction?

    International Nuclear Information System (INIS)

    Karouby, Johanna; Brandenberger, Robert

    2010-01-01

    It was recently realized that matter modeled by the scalar field sector of the Lee-Wick standard model yields, in the context of a homogeneous and isotropic cosmological background, a bouncing cosmology. However, bouncing cosmologies induced by pressureless matter are in general unstable to the addition of relativistic matter (i.e. radiation). Here we study the possibility of obtaining a bouncing cosmology if we add not only radiation, but also its Lee-Wick partner, to the matter sector. We find that, in general, no bounce occurs. The only way to obtain a bounce is to choose initial conditions with very special phases of the radiation field and its Lee-Wick partner.

  2. Lee Acculturation Dream Scale for Korean-American college students.

    Science.gov (United States)

    Lee, Sang Bok

    2005-04-01

    This study examined acculturation as represented in dream narratives of 165 Korean immigrant college students living in the USA. A total of 165 dreams were collected and evaluated using the Lee Acculturation Dream Scale, for which locations of dream contents were coded. 39% of the dreams took place in South Korea, while 38% were in the USA. Also, 16% of the dreams included both locations, whereas 7% had no specific dream location. The dreams contained overlapping dream messages, images, scenes, and interactions in both South Korea and the USA. A two-sample t test on the mean scores of the Lee Acculturation Dream Scale indicated no significant difference between men and women.

  3. Lee-Wick indefinite metric quantization: A functional integral approach

    International Nuclear Information System (INIS)

    Boulware, D.G.; Gross, D.J.

    1984-01-01

    In an attempt to study the stability of the Lee-Wick indefinite metric theory, the functional integral for indefinite metric quantum field theories is derived. Theories with an indefinite classical energy may be quantized with either a normal metric and an indefinite energy in Minkowski space or an indefinite metric and a positive energy in euclidean space. However, the functional integral in the latter formulation does not incorporate the Lee-Wick prescription for assuring the unitarity of the positive energy positive metric sector of the theory, hence the stability of the theory cannot be studied non-perturbatively. (orig.)

  4. Russell's Unknown Logicism A Study in the History and Philosophy of Mathematics

    CERN Document Server

    Gandon, Professor Sebastien

    2012-01-01

    In this excellent book Sebastien Gandon focuses mainly on Russell's two major texts, Principa Mathematica and Principle of Mathematics, meticulously unpicking the details of these texts and bringing a new interpretation of both the mathematical and the philosophical content.

  5. Lee de Forest King of Radio, Television, and Film

    CERN Document Server

    Adams, Mike

    2012-01-01

    Lee de Forest, Yale doctorate and Oscar winner, gave voice to the radio and the motion picture. Yet by the 1930s, after the radio and the Talkies were regular features of American life, Lee de Forest had seemingly lost everything. Why? Why didn’t he receive the recognition and acclaim he sought his entire life until years later in 1959, when he was awarded an Oscar? A lifelong innovator, Lee de Forest invented the three-element vacuum tube which he developed between 1906 and 1916 as a detector, amplifier, and oscillator of radio waves. As early as 1907, he was broadcasting music programming. In 1918, he began to develop a system for recording and playing back sound by using light patterns on motion picture film. In order to promote and demonstrate his process he made hundreds of short sound films, found theatres for their showing, and issued publicity to gain audiences for his invention. While he received many patents for this technology, he was ignored by the film industry. Lee de Forest, King of Radio, Te...

  6. Must Historians Regress? An Answer to Lee Benson.

    Science.gov (United States)

    Kousser, J. Morgan

    1986-01-01

    Considers the impact of empirical social science methodology and data analysis techniques on the process of historical analysis and its product, generalizations about the past. Uses political preference and voting information as a vehicle to illustrate the differences in historical conclusions reached by Lee Benson and J. Morgan Kousser. (JDH)

  7. The Garrett Lee Smith Memorial Suicide Prevention Program

    Science.gov (United States)

    Goldston, David B.; Walrath, Christine M.; McKeon, Richard; Puddy, Richard W.; Lubell, Keri M.; Potter, Lloyd B.; Rodi, Michael S.

    2010-01-01

    In response to calls for greater efforts to reduce youth suicide, the Garrett Lee Smith (GLS) Memorial Act has provided funding for 68 state, territory, and tribal community grants, and 74 college campus grants for suicide prevention efforts. Suicide prevention activities supported by GLS grantees have included education, training programs…

  8. Sieve bootstrapping in the Lee-Carter model

    NARCIS (Netherlands)

    Heinemann, A.

    2013-01-01

    This paper studies an alternative approach to construct confidence intervals for parameter estimates of the Lee-Carter model. First, the procedure of obtaining confidence intervals using regular nonparametric i.i.d. bootstrap is specified. Empirical evidence seems to invalidate this approach as it

  9. Robert E. Lee, George Peabody, and Sectional Reunion.

    Science.gov (United States)

    Parker, Franklin

    1994-01-01

    Discusses an 1869 meeting between George Peabody, educational philanthropist, and Robert E. Lee. The meeting focused public attention on the Peabody Education Fund and the South's educational plight. Significant measures of educational efforts in the South are directly attributable to several informal meetings centered around Peabody and Lee…

  10. Rejoinder to Goldberg, Lee and Ashton : Explaining counterintuitive findings

    NARCIS (Netherlands)

    Anderson, N.; Ones, D.S.

    2008-01-01

    In their critique of our erratum and addendum (Anderson & Ones, [2008]), Goldberg, Lee, and Ashton ([2008]) allege clerical errors (1) where participants' HPI scores were incorrectly matched to other inventory scale scores and (2) in scoring of the OPQ and BPI scales. The first point was fully

  11. W3C head Berners-Lee to be knighted

    CERN Multimedia

    Gross, G

    2004-01-01

    "Tim Berners-Lee, credited with inventing the World Wide Web and now director of the World Wide Web Consortium, will be named a knight commander, Order of the British Empire, by Queen Elizabeth II, the W3C announced Wednesday" (1 page)

  12. Virginia Lee Burton's "Little House" in Popular Consciousness

    DEFF Research Database (Denmark)

    Goddard, Joseph

    2011-01-01

    This article considers the significance of Victoria Lee Burton’s authorship, specifically The Little House, for lifestyle preferences and the development of environmental consciousness in the postwar period. The article argues that Burton deliberately designed her work to evoke country-friendly s...

  13. Berners-Lee wins inaugural Millennium Technology prize

    CERN Multimedia

    2004-01-01

    "World Wide Web inventor Tim Berners-Lee today was named recipient of the first-ever Millennium Technology Prize. The honor, which is accompanied by one million euros, is bestowed by the Finnish Technology Award Foundation as an international acknowledgement of outstanding technological innovation aimed at promoting quality of life and sustainable economic and societal development" (1 page)

  14. Tim Berners-Lee, World Wide Web inventor

    CERN Document Server

    1998-01-01

    The "Internet, Web, What's next?" conference on 26 June 1998 at CERN: Tim Berners-Lee, inventor of the World Wide Web and Director of the W3C, explains how the Web came to be and gave his views on the future.

  15. Dan Gilmor Column [Berners-Lee and the WWW

    CERN Multimedia

    Gillmore, D

    2002-01-01

    In the keynote speech at the 11th Annual World Wide Web Conference, Tim Berner's Lee said that in the early days of the web, people were worrying about the same thing as today - one company dominating the market and controlling standards (2 pages).

  16. O Platonismo de Russell na metafísica e na matemática

    Directory of Open Access Journals (Sweden)

    Guido Imaguire

    2005-06-01

    Full Text Available Neste artigo, analiso o surgimento e a superação do Platonismo em B. Russell, tanto na sua filosofia da matemática como na sua metafísica. Começo por explicitar os argumentos que levaram Russell a aderir ao chamado "Platonismo Proposicional" - posição que será tecnicamente relevante na definição de números. Na seção seguinte, discutirei até que ponto a teoria das descrições definidas determina, necessariamente, uma adesão ao nominalismo, e as dificuldades que surgem para o logicismo conseqüentes do abandono do platonismo. Finalmente, mostrarei como a posição madura de Russell caracteriza-se mais como um reducionismo do que propriamente como um nominalismo, e como este é fundado no princípio do mínimo vocabulário.In this paper, I analyze the emergence and the overcoming of Platonism both in Russell's philosophy of mathematics and his metaphysics. I begin by examining the arguments which led Russell to endorse a position that I term "Propositional Platonism" - this position proves to be relevant for Russell's definition of numbers. In the following section, I address the question of the extent to which Russell's theory of descriptions implies the acceptance of nominalism. Moreover, I examine the difficulties which arise for logicism, if it no longer goes hand in hand with platonism. Finally, I argue argue that Russell's mature position is to be characterized as a form of reductionism rather than as a variant of nominalism

  17. Supratentorial juvenile pilocytic astrocytoma in a young adult with Silver-Russell syndrome.

    LENUS (Irish Health Repository)

    Fenton, E

    2008-12-01

    Silver-Russell syndrome is a rare genetically heterogeneous disorder in which patients demonstrate intrauterine and postnatal growth retardation, triangular facies, excessive sweating during early childhood, late closure of the anterior fontanelle and skeletal asymmetry. An association with malignancy exists and only one previous intracranial tumour has been reported, a craniopharyngioma. We report the first case of Silver-Russell syndrome associated with a supratentorial juvenile pilocytic astrocytoma.

  18. The neurological legacy of John Russell Reynolds (1828-1896).

    Science.gov (United States)

    Eadie, M J

    2007-04-01

    Sir John Russell Reynolds was an eminent and highly influential physician in the Victorian era who held the Presidencies of the Royal College of Physicians of London, and of the British Medical Association. He was the protégée of the great experimental physiologist, Marshall Hall, who discovered the reflex arc, and succeeded to Hall's clinical practice in London. Reynolds' thought and clinical activities linked the emerging British neurology of the first half of the 19th century with its blossoming, particularly in London, from 1860 onwards. In his writings Reynolds was the first English author to apply the approach to classification of neurological disorders that is still often used, though now in modified form. He was also the first to enunciate the notion of positive and negative symptoms arising from neurological disease and to suggest their pathogenesis, and was arguably the originator of the influential concept that an idiopathic disease, epilepsy, existed, one to be distinguished from 'epileptiform' seizures due to brain pathology.

  19. SINDROME DE SILVER-RUSSELL, REPORTE DE UN CASO

    Directory of Open Access Journals (Sweden)

    Ángela Liliana Grandas Ramírez

    2012-12-01

    Full Text Available El síndrome Silver-Russell es un desorden genético (hipometilación en la región centro 1 (ICR1 del  IGF2 /H19  locus 11p15 y clínicamente heterogéneo, caracterizado por retardo del crecimiento intrauterino, baja talla y peso, y perímetro cefálico normal. Su tratamiento se basa en la  hormona del crecimiento. Se presenta el caso de una niña de 5 años que ingresa al servicio de Estomatología Pediátrica de la Fundación HOMI Hospital de la Misericordia de Bogotá, con antecedente de retardo del crecimiento intrauterino, manejada con dieta rica en carbohidratos y uso de biberón hasta los 2 y medio años, Al examen talla 88 cm y peso 9 Kg,  cara forma triangular, frente prominente, micrognatismo mandibular, apiñamiento dental y caries de la infancia temprana. Se diagnostica con retardo de la edad ósea, dental y morfológica. El tratamiento programa individual riesgo de caries y proveer una alta calidad de salud oral.

  20. The Solar Eclipse Mural Series by Howard Russell Butler

    Science.gov (United States)

    Pasachoff, J. M.; Olson, R. J. M.

    2016-01-01

    There is a rich trove of astronomical phenomena in works of art by artists from the greater New York area, a trend that is even more pronounced in the oeuvres of New York City residents through the present day. A case in point is the trio of oil paintings by artist (and former physics professor) Howard Russell Butler depicting total solar eclipses in 1918, 1923, and 1925 that are based on his own observations. They were long displayed in the former art-deco building of the Hayden Planetarium of the American Museum of Natural History, the location of this conference. (The Museum also has nine other Butler paintings, none of which are currently exhibited.) Since the eclipse paintings have been in storage for many years, these once famous works are now virtually forgotten. Based on our research as an astronomer who has seen sixty-two solar eclipses and an art historian who has written extensively about astronomical imagery, we will discuss Butler's Solar Eclipse Triptych to explore its place in the history of astronomical imaging.

  1. Nooruslikud juubilarid: fotokelder Lee 20 ja fotomuuseum 30 / Mall Parmas, Betty Ester-Väljaots

    Index Scriptorium Estoniae

    Parmas, Mall

    2013-01-01

    Peeter Toominga algatusel 1992. aastal asutatud Lee fotokeldrist. Loetletud fotomuuseumis oma töid eksponeerinud fotograafid. Ülevaatenäitus "Lee fotokelder 20" 17. jaanuarist 20. märtsini, koostaja Betty Ester-Väljaots

  2. Vafa-Witten theorem and Lee-Yang singularities

    International Nuclear Information System (INIS)

    Aguado, M.; Asorey, M.

    2009-01-01

    We prove the analyticity of the finite volume QCD partition function for complex values of the θ-vacuum parameter. The absence of singularities different from Lee-Yang zeros only permits and cusp singularities in the vacuum energy density and never or cusps. This fact together with the Vafa-Witten diamagnetic inequality implies the vanishing of the density of Lee-Yang zeros at θ=0 and has an important consequence: the absence of a first order phase transition at θ=0. The result provides a key missing link in the Vafa-Witten proof of parity symmetry conservation in vectorlike gauge theories and follows from renormalizability, unitarity, positivity, and existence of Bogomol'nyi-Prasad-Sommerfield bounds. Generalizations of this theorem to other physical systems are also discussed, with particular interest focused on the nonlinear CP N sigma model.

  3. Lee Miller, une battante sur tous les fronts

    Directory of Open Access Journals (Sweden)

    Anaïs Boutot

    2009-06-01

    Full Text Available L’art photographique de Lee Miller, à l’image de sa vie, revêt de multiples facettes. Après avoir été devant l’objectif en tant que mannequin puis égérie du Paris surréaliste, elle passe derrière l’objectif pour devenir photographe de mode, reporter de guerre ou encore portraitiste. L’exposition L’Art de Lee Miller, présentée au Jeu de Paume du 21 octobre 2008 au 4 janvier 2009 et accompagnée d’un ouvrage paru en français chez Hazan mettait en avant une quête d’identité et d’indépendance qui ...

  4. Economist Innovation Award for Tim Berners-Lee

    CERN Multimedia

    2003-01-01

    In September, Tim Berners-Lee, who invented the World Wide Web at CERN and is now Director of the W3C World Wide Web Consortium, received the 2nd Economist Annual Innovation Award in Computing. With the award The Economist, a British weekly newspaper, recognises individuals responsible for breakthroughs in Bioscience, Computing, Energy and the Environment, and Telecommunications that have a profound impact on industry. A fifth award is given in a special "No Boundaries" category, observing innovation that transcends industries. Candidates for the awards are proposed by The Economist readers and writers, and by a group of judges. Tim Berners-Lee received the Computing award for his global hypertext project, to be known as the World Wide Web, which "forever altered the way information is shared" and is a huge contribution to the efficiency of the scientific community. Based on a programme for storing information using random associations called "Enquire", it...

  5. What Lee Raymond actually said in Beijing [15th WPC

    International Nuclear Information System (INIS)

    Raymond, Lee.

    1997-01-01

    When Lee Raymond, Chairman and Chief Executive Officer, Exxon Corporation gave this keynote address at the recent World Petroleum Congress in Beijing, he drew attention to the way economic growth alleviates poverty and to the close linkage between economic growth and energy use. He also drew attention to the weakness of the scientific evidence for climate change being caused by fossil fuel burning and his doubts about the wisdom of setting targets for the reduction of CO 2 emissions. At a press conference after the presentation Lee Raymond assented to the suggestion that the European oil companies have been hijacked by the environmentalists. Petroleum Review has reproduced the full text of the speech so that readers can judge for themselves the merits of the arguments and their likely impact on the Kyoto conference. (UK)

  6. Fate of grape flavor precursors during storage on yeast lees.

    Science.gov (United States)

    Loscos, Natalia; Hernández-Orte, Purificación; Cacho, Juan; Ferreira, Vicente

    2009-06-24

    The effect of the addition of a grape flavor precursor extract to a grape juice, before or after fermentation with three different Saccharomyces cerevisiae yeast strains, on the evolution of the wine aroma composition during a 9-month aging period on yeast lees has been studied. Wine aroma compounds were determined by gas chromatography-mass spectrometry after alcoholic fermentation and after 3 and 9 months of storage. The aging of wine on lees caused important changes in the aroma profiles of wines, making the concentrations of three terpenes, norisoprenoids (except beta-damascenone and beta-ionone), 4-allyl-2,6-dimethoxyphenol, ethyl vanillate, syringaldehyde, and ethyl cinnamate increase, whereas the concentrations of most of the rest of compounds tended to decrease. Lees are responsible for the observed increasing trends, except for linalool and alpha-terpineol, and also for a large part of the observed decrements. As expected, the addition of precursors brings about an increment in the levels of most terpenes, norisoprenoids, vanillins, and ethyl cinnamate, and it is after an aging time when differences linked to the level of precursors in the must become more evident. The timing of the addition of precursors has a minor influence, except for beta-damascenone, vanillin, and syringaldehyde, for which supplementation after fermentation is more effective. It has also been observed that the precursor fraction makes the levels of vinylphenols decrease. Finally, it has also been found that lees from different yeast strains may have a slightly different abilities to release volatile compounds derived from precursors.

  7. Gettysburg: A Study of Lee’s Command Effectiveness, 1863

    Science.gov (United States)

    2011-03-21

    scholar of military history it is not necessary to focus strictly on the tactics of a single battle, or campaign, or even an entire war. To fully...the second day was the Peach Orchard and ultimately Cemetery Hill.48 The Peach Orchard was carried at a heavy cost but attacks on Little Round Top...Union troops to occupy the desired ground of the Peach Orchard and obtain positions on Little Round Top. Knowing Longstreet’s nature, Lee did not

  8. Tim Berners-Lee, World Wide Web inventor

    CERN Document Server

    1994-01-01

    Former physicist, Tim Berners-Lee invented the World Wide Web as an essential tool for high energy physics at CERN from 1989 to 1994. Together with a small team he conceived HTML, http, URLs, and put up the first server and the first 'what you see is what you get' browser and html editor. Tim is now Director of the Web Consortium W3C, the International Web standards body based at INRIA, MIT and Keio University.

  9. Triniti daripada Perspektif Taoisme: Analisis Pemikiran Jung Young Lee

    Directory of Open Access Journals (Sweden)

    ZURAIZA HUSIN

    2016-06-01

    Full Text Available Jung Young Lee is a Korean-born theologian who employs creatively the doctrine of the Trinity from an Asian worldview. This article aims to analyze Lee’s approaches of the Trinity with the Yin-Yang symbolism. The main reference is based on the book written by him entitled ‘The Trinity in Asian Perspective (1996’. Lee has turned his attention to the topic of Trinity through the lens of the culture and thought patterns of his own milieu. One of the leading point in presenting Yin-Yang principle as Trinitarian thinking, Lee examines the interpretation of the term “in” in the Bible, "Believe me that I am in the Father and the Father is in me" (John 14:11. The statement leads to the point that Yin and Yang cannot exist without each other because relationality is given priority than individuality. The idea is based on the terminology of ‘both/and’. So, ‘and’ indicates a Trinitarian statement, there is interdependence and unification. With reference to Trinity, the Father and the Son are One because of ‘and’. In addition, the same concept implements to the Holy Spirit. Lee views ‘and’ is not only a linking principle in both-and thinking but also the principle that is ‘between’ two. When ‘two’ exists, the third also exist between them. Based on the idea of ‘middle’, represents the connecting element between two, which contributes for the existence of the Third. Accordingly, the Spirit is the third element in the Trinity relationship.

  10. Effects of Tamarind (Tamarindus indicus Linn) seed extract on Russell's viper (Daboia russelli siamensis) venom.

    Science.gov (United States)

    Maung, K M; Lynn, Z

    2012-12-01

    Snake bite has been regarded as an important health problem in Myanmar since early 1960's. In the recent years, there has been growing interest in alternative therapies and therapeutic use of natural products, especially those derive from plants. In Myanmar and Indian traditional medicine, various plants have used as a remedy for treating snake bite. The present study was carried out to evaluate the effects of alcohol extract of Tamarind (Tamarindus indica Linn.) seed on some biologic properties of Russell's viper (Daboia russelli siamensis) venom (RVV). The Phospholipase A2 (PLA2) enzyme, coagulase enzyme and caseinolytic enzyme activities of Russell's viper venom (RVV) were reduced when mixed and incubated with the extract. When the RVV and the different amount of extracts were preincubated and injected intramuscularly into mice, all of them survived, but all the mice in the control group died. On the other hand, when RVV were injected first followed by the extract into mice, all of them died. If the extract was injected near the site where Russell's viper venom was injected, all the mice survived for more than 24 hours and the survival time prolonged but they all died within 96 hours. In conclusion, according to the results obtained, the extract neutralizes some biologic properties of the Russell's viper venom and prolonged the survival time if the extract was injected near the site where the Russell's viper venom was injected.

  11. The life and viper of Dr Patrick Russell MD FRS (1727-1805): physician and naturalist.

    Science.gov (United States)

    Hawgood, B J

    1994-11-01

    It is nearly two hundred years since the publication in 1796 of An Account of Indian Serpents collected on the Coast of Coromandel by Patrick Russell. Within the folio is a drawing and description of the venomous snake called Katuka Rekula Poda in the local Telugu language, whose venom was shown experimentally by Dr Russell to be nearly as lethal as that of Cobra de Capello. The snake is now known as Vipera russelli or Russell's viper. Dr Russell was representative of the naturalistic tendency of British medicine in the late 18th century. He was a keen observer and skilled doctor in clinical practice, particularly in Aleppo, Syria, during an outbreak of the plague, and indefatigable in his study of plant and animal life both in Aleppo and later in the Madras Province of India. As a physician as well as Naturalist to the East India Company in the Carnatic he was concerned with the problem of snakebite. His first aim was to find a means whereby the non-specialist could distinguish between poisonous and harmless snakes and so combat the terrible notion that all bites were mortal. His writing, encompassing social and natural histories and climaxed by a study of snakes, has left a rich legacy. Dr Patrick Russell was a man of the highest integrity and ability, a physician and naturalist par excellence.

  12. Heredity, development and evolution: the unmodern synthesis of E.S. Russell.

    Science.gov (United States)

    Esposito, Maurizio

    2013-09-01

    In 1930, while R.A. Fisher, J.B.S. Haldane, E.B. Ford and S.G. Wright were laying the foundations of what a decade later J.S. Huxley dubbed "Modern Synthesis", E.S. Russell published a groundbreaking work, The Interpretation of Development and Heredity. In this book Russell not only condemned Mendelian genetics and neo-Darwinism, but also proposed an alternative synthesis unifying heredity, development, and evolution. The book did not represent the work of a mind operating in isolation. Rather, it was a synthetic work connecting ideas and doctrines of many influential scientists working in Europe and the USA. Through the analysis of archival documents and rarely or never mentioned sources, this article provides an unconventional picture of Russell's theoretical biology. It will be shown that Russell was an international celebrity; he was at the centre of a large network of scholars who shared his ideas and insights. He was one of several biologists arguing for a different synthesis; a synthesis perhaps less visible, less institutionalised, and less 'modern', nevertheless with its influential advocates and international support. Finally, this study shows that Russell's synthesis was not rooted in the classic pantheon of towering figures in the history of biology, i.e. Darwin, Wallace, and Mendel, but was based on the teachings of Kant, Goethe, Cuvier, von Baer, and Müller.

  13. Russell and Burch's 3Rs Then and Now: The Need for Clarity in Definition and Purpose

    Science.gov (United States)

    Tannenbaum, Jerrold; Bennett, B Taylor

    2015-01-01

    Russell and Burch's The Principles of Humane Experimental Technique was first published in 1959. A Special Edition containing the original text was reissued in 1992, after its ideas had gained widespread interest in the scientific community. In the Principles, Russell and Burch proposed a new applied science that would improve the treatment of laboratory animals while advancing the quality of science in studies that use animals. They introduced and defined the terms replacement, reduction, and refinement, which subsequently have become known as ‘alternatives’ or ‘alternative methods’ for minimizing the potential for animal pain and distress in biomedical research. Here we describe and explain the original definitions of the 3Rs in the Principles, examine how current definitions differ among themselves and from Russell and Burch's definitions, and suggest relevant considerations for evaluating all definitions of the 3Rs. PMID:25836957

  14. Russell and Burch's 3Rs then and now: the need for clarity in definition and purpose.

    Science.gov (United States)

    Tannenbaum, Jerrold; Bennett, B Taylor

    2015-03-01

    Russell and Burch's The Principles of Humane Experimental Technique was first published in 1959. A Special Edition containing the original text was reissued in 1992, after its ideas had gained widespread interest in the scientific community. In the Principles, Russell and Burch proposed a new applied science that would improve the treatment of laboratory animals while advancing the quality of science in studies that use animals. They introduced and defined the terms replacement, reduction, and refinement, which subsequently have become known as 'alternatives' or 'alternative methods' for minimizing the potential for animal pain and distress in biomedical research. Here we describe and explain the original definitions of the 3Rs in the Principles, examine how current definitions differ among themselves and from Russell and Burch's definitions, and suggest relevant considerations for evaluating all definitions of the 3Rs.

  15. 75 FR 77665 - Frank Russell Company, Administrative Service Center, Including On-Site Leased Workers From Volt...

    Science.gov (United States)

    2010-12-13

    ... Employment and Training Administration Frank Russell Company, Administrative Service Center, Including On..., Administrative Service Center, Tacoma, Washington. The notice was published in the Federal Register on August 13..., Washington location of Frank Russell Company, Administrative Service Center. The Department has determined...

  16. Phenolic characterization of aging wine lees: Correlation with antioxidant activities.

    Science.gov (United States)

    Romero-Díez, R; Rodríguez-Rojo, S; Cocero, M J; Duarte, C M M; Matias, A A; Bronze, M R

    2018-09-01

    Aging wine lees are water-wastes produced during the wine aging inside wood barrels that can be considered as alternative sources of bioactive compounds. Phenolic characterization and antioxidant activity (AA) measurements of wines lees solid-liquid extracts have been undertaken on a dry extract (DE) basis. Solvents with different polarities (water, methanol, ethanol, two hydroalcoholic mixtures and acetone) were used. Total phenolic (TPC) and total flavonoid contents (TFC) were determined. The mixture of 75:25(v/v) EtOH:H 2 O showed the highest values with 254 mg GAE /g DE and 146 mg CATE /g DE respectively. HORAC, HOSC and FRAP were used to determine the AA of the extracts being also highest for the mixture of 75:25(v/v) EtOH:H 2 O (4690 µmol CAE /g DE , 4527 µmol TE /g DE and 2197 µmol TE /g DE , respectively). For ORAC method, methanol extract showed the best value with 2771 µmol TE /g DE . Correlations between TPC, TFC, phenolic compounds and AA were determined. Most relevant compounds contributing to AA were identified using data from mass spectrometry, being mainly anthocyanins. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. T.D Lee and Lisa Randall visit ATLAS

    CERN Multimedia

    Pauline Gagnon

    Professor Tsung-Dao Lee, who received the Nobel Prize for Physics in 1957 for postulating that parity is not conserved in weak interactions, visited the ATLAS detector this month. He is seen here in the company of Peter Jenni, spokesperson for ATLAS. T.D. Lee is still very active at over 80, pursuing his theory work to this day. Professor Lisa Randall from Harvard University, the well-known theorist behind the Randall-Sundrum theory for extra dimensions, was also part of the group visiting the ATLAS detector. She is seen here with Fabiola Gianotti, deputy spokesperson for ATLAS. Lisa Randall's two initial papers have been quoted both more than 2500 times, making her the most cited theoretical physicist in the world in the last five years as of last autumn - a total of about 10,000 citations! One wonders here if Peter is pointing to a CP-violating graviton spotted in the ATLAS cavern... From left to right: Fabiola Gianotti, Gustaaf Brooijmans, convener of the ATLAS Exotics physics gro...

  18. Inventing Orientation and Mobility Techniques and Teaching Methods: A Conversation with Russell Williams (Part 2)

    Science.gov (United States)

    Welsh, Rachard L.

    2005-01-01

    This is the final part of the adaptation from my on-stage conversation with Russell Williams at the 1998 International Mobility conference in Atlanta, GA, which attempted to highlight Williams's contributions to the progression of orientation and mobility from the Army's immediate response to the service men and women who lost their sight during…

  19. Inventing Orientation and Mobility Techniques and Teaching Methods: A Conversation with Russell Williams

    Science.gov (United States)

    Welsh, Richard L.

    2005-01-01

    Russell C. Williams was a key figure in the progression of orientation and mobility from the Army's immediate response to the servicemen and women who lost their sight during World War II to a recognized profession delivering individualized instruction to visually impaired people throughout the world. Blinded in combat while serving in the U.S.…

  20. Researcher Profile: An Interview with Russell James, JD, PhD, CFP(R)

    OpenAIRE

    Russell James

    2014-01-01

    Russell James is a professor and the CH Foundation Chair in Personal Financial Planning in the Department of Personal Financial Planning at Texas Tech University, where he is also the Director of Graduate Studies in Charitable Financial Planning. His research is focused on encouraging generosity and satisfaction in financial decision-making.

  1. Researcher Profile: An Interview with Russell James, JD, PhD, CFP(R

    Directory of Open Access Journals (Sweden)

    Russell James

    2014-03-01

    Full Text Available Russell James is a professor and the CH Foundation Chair in Personal Financial Planning in the Department of Personal Financial Planning at Texas Tech University, where he is also the Director of Graduate Studies in Charitable Financial Planning. His research is focused on encouraging generosity and satisfaction in financial decision-making.

  2. 76 FR 14101 - Bruss North America; Russell Springs, KY; Bruss North America; Orion, MI; Amended Revised...

    Science.gov (United States)

    2011-03-15

    ... America; Russell Springs, KY; Bruss North America; Orion, MI; Amended Revised Determination on... relevant time period at the Orion, Michigan location of Bruss North America, Inc. The Orion, Michigan..., Kentucky facility also led to worker separations at the Orion, Michigan location during the relevant time...

  3. Venom Concentrations and Clotting Factor Levels in a Prospective Cohort of Russell's Viper Bites with Coagulopathy.

    Directory of Open Access Journals (Sweden)

    Geoffrey K Isbister

    Full Text Available Russell's viper envenoming is a major problem in South Asia and causes venom induced consumption coagulopathy. This study aimed to investigate the kinetics and dynamics of venom and clotting function in Russell's viper envenoming.In a prospective cohort of 146 patients with Russell's viper envenoming, we measured venom concentrations, international normalised ratio [INR], prothrombin time (PT, activated partial thromboplastin time (aPTT, coagulation factors I, II, V, VII, VIII, IX and X, and von Willebrand factor antigen. The median age was 39 y (16-82 y and 111 were male. The median peak INR was 6.8 (interquartile range [IQR]: 3.7 to >13, associated with low fibrinogen [median,3 at 6 h post-antivenom but had reduced to <2, by 24 h. The aPTT had also returned to close to normal (<50 sec at 24 h. Factor VII, VIII and IX levels were unusually high pre-antivenom, median peak concentrations of 393%, 307% and 468% respectively. Pre-antivenom venom concentrations and the INR (r = 0.20, p = 0.02 and aPTT (r = 0.19, p = 0.03 were correlated (non-parametric Spearman analysis.Russell's viper coagulopathy results in prolonged aPTT, INR, low fibrinogen, factors V, VIII and X which recover over 48 h. Severity of clotting abnormalities was associated with venom concentrations.

  4. Visualizing, Rather than Deriving, Russell-Saunders Terms: A Classroom Activity with Quantum Numbers

    Science.gov (United States)

    Coppo, Paolo

    2016-01-01

    A 1 h classroom activity is presented, aimed at consolidating the concepts of microstates and Russell-Saunders energy terms in transition metal atoms and coordination complexes. The unconventional approach, based on logic and intuition rather than rigorous mathematics, is designed to stimulate discussion and enhance familiarity with quantum…

  5. Retrenchment: General Russell E. Dougherty and the Strategic Air Command During the Age of Detente

    Science.gov (United States)

    2014-06-01

    Gerry accompanied Russell back to Columbus, Mississippi after the wedding . They were only in Columbus for two months when Dougherty received orders...The Omaha World Herald covered the retirement ceremony , which was attended by then Air Force Chief of Staff General David C. Jones and former Chief of

  6. Robert E. Lee as Operational Artist During the American Civil War

    Science.gov (United States)

    2010-04-21

    Johnston was just as arrogant as Davis. During his tenure as a student at the United States Military Academy Johnston eamed the nickname "Colonel" from his...shown previous subordinate leaders .. Lee had certainly eamed it based on his reputation and performance at Second Manassas and during his tenure as...Washington, PA: EasternNational. Roland, Charles P. 1964. The Generalship of Robert E. Lee. In Grant, Lee, Lincoln and The Radicals; Essays on

  7. A man before his time: Russell's insights into nicotine, smoking, treatment and curbing the smoking problem.

    Science.gov (United States)

    McNeill, Ann; Robson, Debbie

    2018-04-01

    This narrative review aimed to provide a brief overview of five key research 'classics' produced by the innovative and radical thought leader, Professor Michael Anthony Hamilton Russell (1932-2009), drawing upon his other work wherever feasible. Narrative review. From more than 250 publications, we selected papers we considered seminal texts, published in 1971, 1976, 1978, 1979 and 1991. Russell was among the first researchers to explain that smoking was a dependence disorder caused by the drug nicotine decades before this was recognized formally. He therefore saw quickly the importance of delivering nicotine in a less harmful format as a way of controlling nicotine withdrawal when stopping smoking, first studying nicotine gum. In addition to pharmacotherapies, Russell's research also explored the role of behavioural support, particularly the role of general practitioners (GPs), alone as well as supported by specialist clinics; this research underpinned initiatives in England to reimburse doctors for giving advice to smokers, and to provide a national network of smoking cessation services. Research on nicotine uptake from other delivery systems and routes led Russell to theorize that the speed and dose of delivery impacted upon the effectiveness of a product to act as a substitute for smoking. He commented on the addictiveness of the high nicotine boli delivered in quick succession when smoking cigarettes and argued that alternative recreational nicotine delivery systems would need to be promoted actively to smokers in order for them to compete with cigarettes, a forerunner for contemporary debates on electronic cigarettes. The legacy of Russell's landmark research is seen in present-day nicotine science, policy and discourse. © 2017 Society for the Study of Addiction.

  8. Wrong vertex displacements due to Lee-Wick resonances at LHC

    International Nuclear Information System (INIS)

    Alvarez, E.; Schat, C.; Rold, L. da; Szynkman, A.

    2009-01-01

    We show how a resonance from the recently proposed Lee-Wick Standard Model could lead to wrong vertex displacements at LHCb. We study which could be the possible 'longest lived' Lee-Wick particle that could be created at LHC, and we study its possible decays and detections. We conclude that there is a region in the parameter space which would give wrong vertex displacements as a unique signature of the Lee-Wick Standard Model at LHCb. Further numerical simulation shows that LHC era could explore these wrong vertex displacements through Lee-Wick leptons below 500 GeV. (author)

  9. The Friedberg-Lee symmetry and minimal seesaw model

    International Nuclear Information System (INIS)

    He Xiaogang; Liao Wei

    2009-01-01

    The Friedberg-Lee (FL) symmetry is generated by a transformation of a fermionic field q to q+ξz. This symmetry puts very restrictive constraints on allowed terms in a Lagrangian. Applying this symmetry to N fermionic fields, we find that the number of independent fields is reduced to N-1 if the fields have gauge interaction or the transformation is a local one. Using this property, we find that a seesaw model originally with three generations of left- and right-handed neutrinos, with the left-handed neutrinos unaffected but the right-handed neutrinos transformed under the local FL translation, is reduced to an effective theory of minimal seesaw which has only two right-handed neutrinos. The symmetry predicts that one of the light neutrino masses must be zero.

  10. Searching for Lee-Wick Gauge Bosons at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Rizzo, Thomas G.

    2007-04-30

    In an extension of the Standard Model(SM) based on the ideas of Lee and Wick, Grinstein, O'Connell and Wise have found an interesting way to remove the usual quadratically divergent contributions to the Higgs mass induced by radiative corrections. Phenomenologically, the model predicts the existence of Terascale, negative-norm copies of the usual SM fields with rather unique properties: ghost-like propagators and negative decay widths, but with otherwise SM-like couplings. The model is both unitary and causal on macroscopic scales. In this paper we examine whether or not such states with these unusual properties can be uniquely identified as such at the LHC. We find that in the extended strong and electroweak gauge boson sector of the model, which is the simplest one to analyze, such an identification can be rather difficult. Observation of heavy gluon-like resonances in the dijet channel offers the best hope for this identification.

  11. THE YUAN-TSEH LEE ARRAY FOR MICROWAVE BACKGROUND ANISOTROPY

    International Nuclear Information System (INIS)

    Ho, Paul T. P.; Altamirano, Pablo; Chang, C.-H.; Chang, S.-H.; Chang, S.-W.; Chen, C.-C.; Chen, K.-J.; Chen, M.-T.; Han, C.-C.; Ho, West M.; Huang, Y.-D.; Hwang, Y.-J.; Ibanez-Romano, Fabiola; Jiang Homin; Koch, Patrick M.; Kubo, Derek Y.; Li, C.-T.; Lim, Jeremy; Lin, K.-Y.; Liu, G.-C.

    2009-01-01

    The Yuan-Tseh Lee Array for microwave background anisotropy is the first interferometer dedicated to study the cosmic microwave background radiation at 3 mm wavelength. The choice of 3 mm is to minimize the contributions from foreground synchrotron radiation and Galactic dust emission. The initial configuration of seven 0.6 m telescopes mounted on a 6 m hexapod platform was dedicated in 2006 October on Mauna Loa, Hawaii. Scientific operations began with the detection of a number of clusters of galaxies via the thermal Sunyaev-Zel'dovich effect. We compare our data with Subaru weak-lensing data to study the structure of dark matter. We also compare our data with X-ray data to derive the Hubble constant.

  12. Perturbative unitarity of Lee-Wick quantum field theory

    Science.gov (United States)

    Anselmi, Damiano; Piva, Marco

    2017-08-01

    We study the perturbative unitarity of the Lee-Wick models, formulated as nonanalytically Wick rotated Euclidean theories. The complex energy plane is divided into disconnected regions and the values of a loop integral in the various regions are related to one another by a nonanalytic procedure. We show that the one-loop diagrams satisfy the expected, unitary cutting equations in each region: only the physical d.o.f. propagate through the cuts. The goal can be achieved by working in suitable subsets of each region and proving that the cutting equations can be analytically continued as a whole. We make explicit calculations in the cases of the bubble and triangle diagrams and address the generality of our approach. We also show that the same higher-derivative models violate unitarity if they are formulated directly in Minkowski spacetime.

  13. ‘Dolls in Agony’: Vernon Lee in Southern Spain

    OpenAIRE

    Barrera-Medrano, Leire

    2016-01-01

    Lorsque Vernon Lee se rendit dans le sud de l’Espagne en 1889, elle trouva que les pratiques catholiques qui y étaient exercées étaient extrêmement déroutantes. La décoration excessive des églises et le penchant local pour des représentations sanglantes du Christ en croix étaient, d’après elle, « obscènes » et « excessives ». En particulier, la représentation des Madones espagnoles, constamment figurées éplorées, lui répugnait. Ce sentiment de rejet envers ce pays catholique et plus particuli...

  14. A multi-developing-country comparison of the lee-carter model for ...

    African Journals Online (AJOL)

    This study evaluate the Lee-Carter model for projecting age and gender specific mortality rates and life expectancy at births in four developing countries namely Malaysia, Indonesia, Thailand and Singapore. Although the Lee-Carter model has been successfully applied in many developed countries, little information is ...

  15. Tim Berners-Lee at the RSIS conference from 8-9 December 2003.

    CERN Multimedia

    Patrice Loiez

    2003-01-01

    Tim Berners-Lee participated in the Role of Science in the Information Society conference held at CERN from 8-9 December 2003. Tim Berners-Lee developed the first network and server system that lead to the World Wide Web.

  16. Grain-size sorting in grainflows at the lee side of deltas

    NARCIS (Netherlands)

    Kleinhans, M.G.

    2005-01-01

    The sorting of sediment mixtures at the lee slope of deltas (at the angle of repose) is studied with experiments in a narrow, deep flume with subaqueous Gilbert-type deltas using varied flow conditions and different sediment mixtures. Sediment deposition and sorting on the lee slope of the delta

  17. A Case of Monoclonal Lymphoplasmacytosis of the Bone Marrow with IgM-Positive Russell Bodies

    Directory of Open Access Journals (Sweden)

    Hidekazu Kayano

    2011-01-01

    Full Text Available A 71-year-old Japanese male patient infected with HCV was diagnosed with thrombocytopenia. Histological examination of the bone marrow aspirate showed numerous lymphoid aggregates with Russell bodies. Immunohistochemistry and flow cytometric analysis demonstrated clonal expansion of CD5+ CD23+ B cells. Russell bodies were positive for IgM and lambda immunoglobulin light chain. The patient also underwent gastric biopsy, which revealed Helicobacter pylori (HP infection. Subsequent eradication of the bacteria resulted in improvement of his thrombocytopenia. The clinical course remained uneventful at 15-month follow-up, consistent with monoclonal B-cell lymphocytosis. The observed clonal expansion with plasmacytic differentiation may have occurred under the influence of HCV with HP infection.

  18. Bertrand Russell : [poems] / Jaan Kaplinski ; transl. by the author, ed. by Fiona Sampson

    Index Scriptorium Estoniae

    Kaplinski, Jaan, 1941-

    2003-01-01

    Autori lühitutvustus lk. 266. Sisu: Bertrand Russell ; "Once again I think of what I have read..." ; "I do not feel at home in this synthetic world..." ; "Silence is always here and everywhere..." ; "In the morning, I was presented to President Mitterrand..." ; Evening is coming. The land and the forest meet..." ; " A cloudy afternoon in late autumn..." ; "My poems often aren't poems..." ; "My eyesight's weakening...". Orig.: Bertrand Russell ; Mõtlen taas loetule..." ; "Ei ole kodune siin sünteetilises maailmas..." ; "Vaikus on alati siin..." ; "Hommikul tutvustati mind president Mitterrandile.." ; "Õhtu tuleb ja maa ja mets saavad kokku..." ; "Pilvealune südasügise-pärastlõuna..." ; "Mu luuletused ei ole tihti luuletused..." ; "Silmad on nõrgaks jäänd..."

  19. Finding the courage: the unconventional lives of WMS and Claire Russell.

    Science.gov (United States)

    Paskal, Cleo

    2009-12-01

    WMS and Claire Russell led lives of extraordinary intellectual adventure, spanning from the traditional formal education of Oxford University to the creativity of science fiction and the experimental world of mid-20th Century psychoanalysis. The verbal and pictorial illustrations presented in this article offer an insight into the vast collection of documents related to their lives and work currently being catalogued in the Manuscripts and Special Collections department of the University of Nottingham. 2009 FRAME.

  20. Distinct 15q genotypes in Russell-Silver and ring 15 syndromes

    Energy Technology Data Exchange (ETDEWEB)

    Rogan, P.K.; Seip, J.R. [Pennsylvania State Univ., Hershey, PA (United States); Driscoll, D.J. [Univ. of Florida, Gainesville (United States)] [and others

    1996-03-01

    Individuals with a ring 15 chromosome [r(15)] and those with Russell-Silver syndrome have short stature, developmental delay, triangular face, and clinodactyly. To assess whether the apparent phenotypic overlap of these conditions reflects a common genetic cause, the extent of deletions in chromosome 15q was determined in 5 patients with r(15), 1 patient with del 15q26.1-qter, and 5 patients with Russell-Silver syndrome. All patient with Russell-Silver syndrome were diploid for genetic markers in distal 15q, indicating that Russell-Silver syndrome in these individuals was unlikely to be related to the expression of single alleles at these or linked genetic loci. At least 3 distinct sites of chromosome breakage close to the telomere were found in the r(15) and del 15q25.1-qter patients, with 1 r(15) patient having both a terminal and an interstitial deletion. Although the patient with del 15q25.1-qter exhibited the largest deletion and the most profound growth retardation, the degree of growth impairment among the r(15) patients was not correlated with the size of the deleted interval. Rather, the parental origin of the ring chromosome in several patients was associated with phenotypes that are also seen in patients with either Prader-Willi (PWS) or Angelman (AS) syndromes, conditions that result from uniparental expression of genes on chromosome 15. The PWS-like or AS-like phenotypes could be explained by postzygotic loss of the ring chromosome, leading to uniparental inheritance of the intact chromosome in some tissues of r(15) patients. 33 refs., 2 figs., 3 tabs.

  1. Charles Robert Darwin and Alfred Russel Wallace: their dispute over the units of selection.

    Science.gov (United States)

    Ruse, Michael

    2013-12-01

    Charles Darwin and Alfred Russel Wallace independently discovered the mechanism of natural selection for evolutionary change. However, they viewed the working of selection differently. For Darwin, selection was always focused on the benefit for the individual. For Wallace, selection was as much something of benefit for the group as for the individual. This difference is traced to their different background political-economic views, with Darwin in favor of Adam Smith's view of society and Wallace following Robert Owen in being a socialist.

  2. James Lee Byars 1/2 an autobiography, sourcebook

    CERN Document Server

    Byars, James Lee; Eleey, Peter

    2014-01-01

    "I see my autobiography as an arbitrary segment of so many pages of time, of things that I have paid attention to at this point in my life," wrote James Lee Byars (1932-1997) in 1969. He was then 37, about half the average male lifespan at the time, and accordingly thought it appropriate to write his "1/2 autobiography." Byars' art ranged from highly refined objects to extremely minimal performance and events, and books, ephemera and correspondence that he distributed widely among friends and colleagues. Today, more than 15 years after his death, assessments of his art must negotiate Byars' performance of his charismatic self in his life and art. For his first major posthumous survey in the US, exhibition curators Magalí Arriola and Peter Eleey decided to produce a catalogue in two "halves," playing on his "1/2 autobiography": a catalogue of the exhibition itself, including new scholarship, and a sourcebook of primary documents. 1/2 an Autobiography, Sourcebook constitutes the latter volume--a reference guid...

  3. Clinical and Pharmacological Investigation of Myotoxicity in Sri Lankan Russell's Viper (Daboia russelii Envenoming.

    Directory of Open Access Journals (Sweden)

    Anjana Silva

    2016-12-01

    Full Text Available Sri Lankan Russell's viper (Daboia russelii envenoming is reported to cause myotoxicity and neurotoxicity, which are different to the effects of envenoming by most other populations of Russell's vipers. This study aimed to investigate evidence of myotoxicity in Russell's viper envenoming, response to antivenom and the toxins responsible for myotoxicity.Clinical features of myotoxicity were assessed in authenticated Russell's viper bite patients admitted to a Sri Lankan teaching hospital. Toxins were isolated using high-performance liquid chromatography. In-vitro myotoxicity of the venom and toxins was investigated in chick biventer nerve-muscle preparations. Of 245 enrolled patients, 177 (72.2% had local myalgia and 173 (70.6% had local muscle tenderness. Generalized myalgia and muscle tenderness were present in 35 (14.2% and 29 (11.8% patients, respectively. Thirty-seven patients had high (>300 U/l serum creatine kinase (CK concentrations in samples 24h post-bite (median: 666 U/l; maximum: 1066 U/l. Peak venom and 24h CK concentrations were not associated (Spearman's correlation; p = 0.48. The 24h CK concentrations differed in patients without myotoxicity (median 58 U/l, compared to those with local (137 U/l and generalised signs/symptoms of myotoxicity (107 U/l; p = 0.049. Venom caused concentration-dependent inhibition of direct twitches in the chick biventer cervicis nerve-muscle preparation, without completely abolishing direct twitches after 3 h even at 80 μg/ml. Indian polyvalent antivenom did not prevent in-vitro myotoxicity at recommended concentrations. Two phospholipase A2 toxins with molecular weights of 13kDa, U1-viperitoxin-Dr1a (19.2% of venom and U1-viperitoxin-Dr1b (22.7% of venom, concentration dependently inhibited direct twitches in the chick biventer cervicis nerve-muscle preparation. At 3 μM, U1-viperitoxin-Dr1a abolished twitches, while U1-viperitoxin-Dr1b caused 70% inhibition of twitch force after 3h. Removal of both

  4. Test procedure for the Master-Lee and the modified Champion four inch hydraulic cutters

    International Nuclear Information System (INIS)

    Crystal, J.B.

    1995-01-01

    The Master-Lee and the modified Champion 4 Inch hydraulic cutters are being retested to gather and document information related to the following: determine if the Master-Lee cutters will cut the trunnions of an Aluminum fuel canister and a Stainless Steel fuel canister; determine if the Master-Lee cutters will cut 1 1/2 inch diameter fire hose; determine if the modified Champion 4 inch blade will cut sections of piping; and determine the effectiveness of the centering device for the Champion 4 Inch cutters. Determining the limitations of the hydraulic cutter will aid in the process of debris removal in the K-Basin. Based on a previous test, the cutters were returned to the manufacturer for modifications. The modifications to the Champion 4 Inch Cutter and further testing of the Master-Lee Cutter are the subjects of these feature tests

  5. 75 FR 11225 - Environmental Impact Statement; Lee and Collier Counties, Florida

    Science.gov (United States)

    2010-03-10

    ... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement; Lee and Collier Counties, Florida AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of... INFORMATION CONTACT: Mr. George Hadley, Environmental Programs Coordinator, Federal Highway Administration...

  6. Näitleja Tommy Lee Jonesi meditatsioon režissööritoolis / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2007-01-01

    Vestern "Melquiades Estrada kolm matust" ("The Three Burials of Melquiades Estrada") : stsenarist Guillermo Arriaga : režissöör ja osatäitja Tommy Lee Jones : operaator Chris Menges : Ameerika Ühendriigid, 2005

  7. The Pitzer-Lee-Kesler-Teja (PLKT) Strategy and Its Implementation by Meta-Computing Software

    Czech Academy of Sciences Publication Activity Database

    Smith, W. R.; Lísal, Martin; Missen, R. W.

    2001-01-01

    Roč. 35, č. 1 (2001), s. 68-73 ISSN 0009-2479 Institutional research plan: CEZ:AV0Z4072921 Keywords : The Pitzer-Lee-Kesler-Teja (PLKT) strategy * implementation Subject RIV: CF - Physical ; Theoretical Chemistry

  8. Behind their eyes : identity in the work of Li-Young Lee and Suji Kwock Kim

    OpenAIRE

    Hand, Meadhbh

    2014-01-01

    The introduction to this study outlines the theoretical framework for comparing the work of Li-Young Lee and Suji Kwock Kim. Using Walter Mignolo's theories about "border thinking," which he outlined in Local Histories/Global Designs, alongside Anzaldua's Borderlands/La Frontera as a basis for approaching Kim's and Lee's work, I demonstrate how the poets may be considered as embodying the role of border thinkers. Marianne Hirsch's definition of "postmemory," is explored, and its relevance to ...

  9. Comparative genomics and stx phage characterization of LEE-negative Shiga toxin-producing Escherichia coli

    Directory of Open Access Journals (Sweden)

    Susan Renee Steyert

    2012-11-01

    Full Text Available Infection by Escherichia coli and Shigella species are among the leading causes of death due to diarrheal disease in the world. Shiga toxin producing Escherichia coli (STEC that do not encode the locus of enterocyte effacement (LEE-negative STEC often possess Shiga toxin gene variants and have been isolated from humans and a variety of animal sources. In this study, we compare the genomes of nine LEE-negative STEC harboring various stx alleles with four complete reference LEE-positive STEC isolates. Compared to a representative collection of prototype E. coli and Shigella isolates representing each of the pathotypes, the whole genome phylogeny demonstrated that these isolates are diverse. Whole genome comparative analysis of the 13 genomes revealed that in addition to the absence of the LEE pathogenicity island, phage encoded genes including non-LEE encoded effectors, were absent from all nine LEE-negative STEC genomes. Several plasmid-encoded virulence factors reportedly identified in LEE-negative STEC isolates were identified in only a subset of the nine LEE-negative isolates further confirming the diversity of this group. In combination with whole genome analysis, we characterized the lambdoid phages harboring the various stx alleles and determined their genomic insertion sites. Although the integrase gene sequence corresponded with genomic location, it was not correlated with stx variant, further highlighting the mosaic nature of these phages. The transcription of these phages in different genomic backgrounds was examined. Expression of the Shiga toxin genes, stx1 and/or stx2, as well as the Q genes, were examined with quantitative reverse transcriptase polymerase chain reaction (qRT-PCR assays. A wide range of basal and induced toxin induction was observed. Overall, this is a first significant foray into the genome space of this unexplored group of emerging and divergent pathogens.

  10. The relevance of the Russel-Einstein Manifesto to young people

    International Nuclear Information System (INIS)

    Milne, T.

    1997-01-01

    There are three ways in which the Russel-Einstein Manifesto is relevant to young people are that it conveys the facts about nuclear weapons and nuclear war, it stresses the nuclear danger at a time when it seems remote, and it goes straight to the heart of many problems (not just nuclear ones) when it says 'Remember your humanity and forget the rest'. The Manifesto is relevant because it is important to get young people thinking about peace, it is they who will initiate wars of the future and fight them. All war must end, but the worst of all weapons, the nuclear bomb should go first

  11. Syndrome de Silver Russell: à propos de 3 cas et revue de la ...

    African Journals Online (AJOL)

    Abstract Le syndrome de Silver Russell (SSR) est une maladie génétique rare. Sa prévalence est estimée à 1/100.000. Il s'agit d'une pathologie de l'empreinte parentale, caractérisée par une grande diversité phénotypique. Ses signes cliniques majeurs sont: un retard de croissance intra-utérin sévère, un retard ...

  12. W. Ritchie Russell, A.B. Baker, and Fred Plum: Pioneers of ventilatory management in poliomyelitis.

    Science.gov (United States)

    Wijdicks, Eelco F M

    2016-09-13

    Historically, neurologists were not involved in the day-to-day management of critically ill patients with bulbar poliomyelitis, but some were. The major contributions of 3 neurologists-W. Ritchie Russell, A.B. Baker, and Fred Plum-in the respiratory management of poliomyelitis have not been recognized. Russell's work was instrumental in identifying multiple types of poliomyelitis defined by their respiratory needs, and he advised treatment that varied from simple postural drainage to use of respirators. He participated in the development of the Radcliffe respiratory pump. Baker recognized the essential involvement of the vagal nerve in respiratory distress, but also observed that involvement of vital centers without cranial nerve involvement would lead to irregular and shallow respiration in some patients and in others with marked dysautonomic features. A similar finding of central involvement of respiration was noted by Plum, who also stressed the importance of hypercapnia. Plum emphasized measurements of vital capacity and techniques to minimize trauma with suctioning after tracheostomy. These 3 neurologists understood the importance of airway and ventilator management, which is currently one of the many pillars of neurocritical care. © 2016 American Academy of Neurology.

  13. Simone Weil i Bertrand Russell : Dues reflexions sobre la pau a l'Europa dels anys trenta

    OpenAIRE

    Masalles Feliu, Esteve

    2006-01-01

    Simone Weil i Bertrand Russell havien defensat posicions pacifistes, però davant del nazisme van justificar la guerra. S'han destacat alguns elements de reflexió en el canvi d'actitud: la importància dels mitjans de comunicació, la del llenguatge i del vessant psicològic del poder, la construcció mediàtica de l'enemic i la transcendència política de l'actuació individual i social davant l'Estat. Simone Weil y Bertrand Russell habían dado apoyo a posiciones pacifistas, pero ante el nazismo ...

  14. Characterization and Comparison of Wine Lees by Liquid Chromatography-Mass Spectrometry in High-Resolution Mode.

    Science.gov (United States)

    Delgado de la Torre, M P; Priego-Capote, F; Luque de Castro, M D

    2015-02-04

    Wine lees from 11 different wineries pertaining to two denominations of origin in Spain (La Rioja and Ribera del Duero) have been characterized in this research by LC-MS/MS in high-resolution mode. For this purpose, the wine lees were separated into the liquid phase (imbibed wine from lees) and the solid residue, which was dried and subjected to solid-liquid extraction assisted by microwaves (dried lees). Both fractions were separately analyzed and the fractions from the 11 wineries compared to find similarity in their patterns. The statistical analysis enabled both differences and common aspects in the composition of imbibed wine from lees and dried lees from all wineries to be found. MS/MS tentative identification of representative compounds in each fraction revealed the varied composition of wine lees with special emphasis on flavonoids such as quercetin, myricetin, and malvidin 3-galactoside, identified in extracts of dried lees, or other compounds such as kaempferol 3-(2',3'-diacetylrhamnoside)-7″-rhamnoside, aminocaproic acid, and citric acid, exclusively identified in imbibed wine from lees. The adsorbent capacity of the solid residue justified the high concentration of phenolic compounds in the extracts from solid lees. The differences found in the composition of the two phases support the separated exploitation of them.

  15. Lee-Yang zeros and large-deviation statistics of a molecular zipper

    Science.gov (United States)

    Deger, Aydin; Brandner, Kay; Flindt, Christian

    2018-01-01

    The complex zeros of partition functions were originally investigated by Lee and Yang to explain the behavior of condensing gases. Since then, Lee-Yang zeros have become a powerful tool to describe phase transitions in interacting systems. Today, Lee-Yang zeros are no longer just a theoretical concept; they have been determined in recent experiments. In one approach, the Lee-Yang zeros are extracted from the high cumulants of thermodynamic observables at finite size. Here we employ this method to investigate a phase transition in a molecular zipper. From the energy fluctuations in small zippers, we can predict the temperature at which a phase transition occurs in the thermodynamic limit. Even when the system does not undergo a sharp transition, the Lee-Yang zeros carry important information about the large-deviation statistics and its symmetry properties. Our work suggests an interesting duality between fluctuations in small systems and their phase behavior in the thermodynamic limit. These predictions may be tested in future experiments.

  16. Utilization of a factorial design to study the composting of hydrolyzed grape marc and vinification lees.

    Science.gov (United States)

    Paradelo, Remigio; Moldes, Ana B; Barral, María T

    2010-03-10

    Hydrolyzed grape marc (HGM) is the solid residue generated after the acid hydrolysis of grape marc to obtain hemicellulosic sugars for biotechnological purposes. In this work, HGM containing cellulose and lignin was composted together with vinification lees to obtain plant substrates on a laboratory scale. The effects of temperature (in the range of 20-50 degrees C), concentration of vinification lees (5-100 g/100 g of hydrolyzed grape marc), and concentration of CaCO(3) on the final properties of the composted HGM were studied by means of an experimental plan with factorial structure. The interrelationship between dependent and operational variables was established by models including linear, interaction, and quadratic terms. The most influential variable on the C/N ratio and P, K and Mg contents of composted substrates was the vinification lees concentration followed by the temperature, whereas on Na content and electrical conductivity the most influential variable was the temperature followed by the vinification lees concentration. The results of the incubation experiments indicated that optimal conditions for obtaining plant substrates can be achieved by composting 1:1 mixtures of hydrolyzed grape marc and vinification lees, in the presence of 5 g of CaCO(3)/100 g of HGM. During composting the pH of the mixtures increased from 5.1-6.7 to 7.1-8.1, salinity and water-soluble carbon were reduced in most cases, and the initial phytotoxicity disappeared in all of the mixtures tested.

  17. Practicing psychology in the art gallery: Vernon Lee's aesthetics of empathy.

    Science.gov (United States)

    Lanzoni, Susan

    2009-01-01

    Late nineteenth-century psychologists and aestheticians were fascinated by the study of psychological and physiological aspects of aesthetic response, and the British intellectual and aesthete Vernon Lee was a major participant in this venture. Working outside the academy, Lee conducted informal experiments with Clementina Anstruther-Thomson, recording changes in respiration, balance, emotion, and body movements in response to aesthetic form. In fashioning her aesthetics of empathy, she mined a wealth of psychological theories of the period including motor theories of mind, physiological theories of emotion, evolutionary models of the usefulness of art, and, most prominently, the empathic projection of feeling and movement into form. Lee distributed questionnaires, contributed to scientific journals, carried out her own introspective studies, and debated aesthetics with leading psychologists. This paper critiques the prevailing view of Lee's aesthetics as a displaced sign of her gender or sexuality, and questions her status as simply an amateur in the field of psychology. Instead, I argue that Lee's empirically based empathy theory of art was a significant contribution to debates on psychological aesthetics at the outset of the twentieth century, offering a synthesis of Lipps's mentalistic Einfühlung and sensation-based imitation theories of aesthetic response.

  18. Expression Regulation of Polycistronic lee3 Genes of Enterohaemorrhagic Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Wei-Sheng W Sun

    Full Text Available Enterohaemorrhagic Escherichia coli O157:H7 (EHEC carries a pathogenic island LEE that is consisted mainly of five polycistronic operons. In the lee3 operon, mpc is the first gene and has been reported to down regulate the type-3 secretion system of EHEC when its gene product is over-expressed. Furthermore, mpc has been suggested to have a regulation function via translation but the mechanism remains unclear. To clarify this hypothesis, we dissected the polycistron and examined the translated products. We conclude that translation of mpc detrimentally governs the translation of the second gene, escV, which in turn affects the translation of the third gene, escN. Then sequentially, escN affects the expression of the downstream genes. Furthermore, we located a critical cis element within the mpc open-reading frame that plays a negative role in the translation-dependent regulation of lee3. Using qRT-PCR, we found that the amount of mpc RNA transcript present in EHEC was relatively limited when compared to any other genes within lee3. Taken together, when the transcription of LEE is activated, expression of mpc is tightly controlled by a restriction of the RNA transcript of mpc, translation of which is then critical for the efficient production of the operon's downstream gene products.

  19. [Lee Jungsook, a Korean independence activist and a nurse during the Japanese colonial period].

    Science.gov (United States)

    Kim, Sook Young

    2015-04-01

    This article examines the life of Lee Jungsook, a Korean nurse, as a independence activist during the Japanese colonial period. Lee Jungsook(1896-1950) was born in Bukchung in Hamnam province. She studied at Chungshin girl's high school and worked at Severance hospital. The characteristics and culture of her educational background and work place were very important factors which influenced greatly the life of Lee Jungsook. She learned independent spirit and nationalism from Chungshin girls' high school and worked as nurse at the Severance hospital which were full of intense aspiration for Korea's independence. Many of doctors, professors and medical students were participated in the 3.1 Independence Movement. Lee Jungsook was a founding member of Hyulsungdan who tried to help the independence activists in prison and their families and worked as a main member of Korean Women's Association for Korean Independece and Kyungsung branch of the Korean Red Cross. She was sent to jail by the Japanese government for her independence activism. After being released after serving two years confinement, she worked for the Union for Women's Liberation as a founding member. Lee Joungsook was a great independence activist who had a nursing care spirit as a nurse.

  20. El triángulo de McDowell y otros recursos para trabajar la expresión escrita y los marcadores del discurso en el aula de E/LE

    Directory of Open Access Journals (Sweden)

    Adrián Ombuena Cabanes

    2015-10-01

    Full Text Available En esta comunicación se presentan un conjunto de actividades ordenadas gradualmente siguiendo el triángulo de McDowell: cada actividad se define según el grado de control del docente sobre la tarea de los alumnos. La última actividad es una actividad comunicativa de expresión escrita (EE donde se aprovechan los contenidos vistos a lo largo de la secuencia didáctica. La actividad final consiste en escribir un texto expositivo-argumentativo utilizando marcadores discursivos (MD. No todas las actividades son de EE, pero sí todas están encaminadas a preparar una buena EE (reconocer MD, localizar MD, organizar MD, planificar la EE con MD. Además, en esta secuencia se utilizan actividades de aprendizaje cooperativo (como el puzle de Aronson, cuya aplicación asegura el aprendizaje significativo. Se presenta aquí una propuesta para acercar a los alumnos de E/LE la importancia del uso de MD y de la planificación para lograr una EE satisfactoria.

  1. Algal communities in cryoconite holes on the Russell glacier, Southwest Greenland

    Science.gov (United States)

    Lamsters, Kristaps; Stivrins, Normunds; Karušs, Jānis; Krievāns, Māris; Rečs, Agnis

    2017-04-01

    The surface of the Greenland Ice Sheet in ablation zone has considerably darkened in the last decades, thus absorbing more solar radiation and accelerating ice melting. Darkening of glacier is made of different impurities that reduce surface albedo. These impurities are represented as cryoconite - combination of dust, soot and microorganisms. While mineral dust composes the greatest part of cryoconite, the black carbon is the most solar radiation absorbing constituent. Microorganisms on the ice are concentrated in cryoconite holes, which have long been of scientific interest, but still remain poorly understood. In order to investigate the microbial communities in cryoconite holes, we collected 12 samples from cryoconite holes at 6 sites located on a 2.5 km long transect line on Russell glacier, Southwest Greenland. The first sampling site was set 3 km from glacier margin at 552 m a.s.l. and the last sampling site was 500 m from the glacier margin at 423 m a.s.l. Depth and diameter of each cryoconite hole, as well as pH, temperature and electrical conductivity was measured in situ on July 29, 2017. During microscopic analysis all microcharcoal (10-100 µm), spheroidal carbonaceous particles (soot), pollen, spores and algae were recorded. Principal Component Analysis reveal two clusters of cryoconite holes (located at 423-465 m a.s.l. and 465-552 m a.s.l.) indicating altitudinal differences. Further, our results show that the biomass of green algae Mesotaeniaceae is correlated with temperature. Meanwhile green algae Chlamydomonadaceae correlates with temperature, microcharcoal and soot particle abundance. Our results show that green algae are dominant type of microorganisms inhabiting cryconite holes on the Russell's glacier at least up to distance of 3 km from ice margin. It is contrary to the previous study of Uetake et al. (2010), who found that cyanobacterial (Oscillatoriaceae) community dominated at 510-635 m altitude of the ablation area of Russell glacier in

  2. Duke Power's William Lee says INPO's purpose is solving industry problems, not educating the public

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    Former Institute of Nuclear Power Operations (INPO) head, William Lee thinks that nuclear critics could misuse institute reports on investigations of nuclear plant construction and operation. If so, that would outweigh any public relations benefits of using the reports to inform and educate the public. Lee thinks the best way to gain public confidence is for the industry to perform well. The four-year-old institute was originally formed to improve operations, but recent problems with unfinished plants led to a system of construction audits. By offering guidance to companies building nuclear plants, INPO is meeting competition from utilities such as Duke Power, which is now marketing its expertise in designing and building plants. Lee emphasizes the importance of asking the right questions that will lead to quality control

  3. Practical Improvements to the Lee-More Conductivity Near the Metal-Insulator Transition

    International Nuclear Information System (INIS)

    Desjarlais, Michael P.

    2000-01-01

    The wide-range conductivity model of Lee and More is modified to allow better agreement with recent experimental data and theories for dense plasmas in the metal-insulator transition regime. Modifications primarily include a new ionization equilibrium model, consisting of a smooth blend between single ionization Saha (with a pressure ionization correction) and the generic Thomas-Fermi ionization equilibrium, a more accurate treatment of electron-neutral collisions using a polarization potential, and an empirical modification to the minimum allowed collision time. These simple modifications to the Lee-More algorithm permit a more accurate modeling of the physics near the metal-insulator transition, while preserving the generic Lee-More results elsewhere

  4. Practical improvements to the Lee-More conductivity near the metal-insulator transition

    International Nuclear Information System (INIS)

    Desjarlais, M.P.

    2001-01-01

    The wide-range conductivity model of Lee and More is modified to allow better agreement with recent experimental data and theories for dense plasmas in the metal-insulator transition regime. Modifications primarily include a new ionization equilibrium model, consisting of a smooth blend between single ionization Saha (with a pressure ionization correction) and the generic Thomas-Fermi ionization equilibrium, a more accurate treatment of electron-neutral collisions using a polarization potential, and an empirical modification to the minimum allowed collision time. These simple modifications to the Lee-More algorithm permit a more accurate modeling of the physics near the metal-insulator transition, while preserving the generic Lee-More results elsewhere. (orig.)

  5. Developing a Hybrid Model of Rational-Emotive Therapy and Systemic Family Therapy: A Response to Russell and Morrill.

    Science.gov (United States)

    Guterman, Jeffrey T.

    1991-01-01

    Challenges Russell and Morrill's (1989) assertion that a practical blending of Rational Emotive Therapy (RET) and systemic family therapy is possible. Cautions that a connection between these approaches be made only with an appreciation and respect for these schools' epistemological differences and correspondingly disparate cognitive change…

  6. A Brief Historical Introduction to Solitons and the Inverse Scattering Transform--A Vision of Scott Russell

    Science.gov (United States)

    Debnath, Lokenath

    2007-01-01

    This paper deals with a brief introduction to major remarkable discoveries of the "soliton" and the "inverse scattering transform" in the 1960s. The discovery of the soliton (or the solitary waves) began with the famous physical experiments of the Scottish Engineer and Naval Architect John Scott Russell in the Glasgow-Edinburgh…

  7. 75 FR 39046 - Russell Brands, LLC, Fabrics Division, a Subsidiary of Fruit of the Loom, Including Employees...

    Science.gov (United States)

    2010-07-07

    ... subject firm. The workers are engaged in employment related to the production of yarn dyed woven fabric..., Fabrics Division, a Subsidiary of Fruit of the Loom, Including Employees Working Off-Site In New York..., 2009, applicable to workers of Russell Brands, LLC, Fabrics Division, a subsidiary of Fruit of the Loom...

  8. Síndrome de Russel ou síndrome de Diencefálica de emagreciemento

    Directory of Open Access Journals (Sweden)

    Nelson Pires Ferreira

    1971-06-01

    Full Text Available Os autores relatam um caso de síndrome de Russel ou síndrome diencefálica do emagrecimento. Revisam a literatura disponível sobre o assunto e comentam a dificuldade do diagnóstico na fase inicial da doença.

  9. Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli

    Directory of Open Access Journals (Sweden)

    Kaparakis Maria

    2009-02-01

    Full Text Available Abstract Background Enteropathogenic Escherichia coli (EPEC is an attaching and effacing (A/E pathogen that possesses a type III secretion system (T3SS encoded within the locus of enterocyte effacement (LEE. The LEE is essential for A/E lesion formation and directs the secretion and translocation of multiple LEE-encoded and non-LEE encoded effector proteins into the cytosol of infected cells. In this study we used proteomics to compare proteins exported to the culture supernatant by wild type EPEC E2348/69, a ΔespADB mutant and a ΔescF T3SS mutant. Results We observed that flagellin was consistently and strongly present in the secretome of wild type EPEC and the ΔespADB mutant but present only weakly in the secretome of the ΔescF mutant. Given the ancestral relationship between the flagella export apparatus and virulence associated T3SSs, we investigated whether FliC could utilise the LEE-encoded T3SS for export. In the absence of a functional flagella export apparatus, we showed that FliC could be secreted by the LEE-encoded T3SS and stimulate (Toll-like receptor 5 TLR5 signalling but could not confer motility. Conclusion Since the secretion of FliC during A/E lesion formation would presumably be disadvantageous for the pathogen, we propose that virulence associated T3SSs and flagella T3SSs have evolved through a system of chaperones and complex regulatory pathways to be functional at different times to ensure that FliC secretion does not occur during T3SS effector translocation.

  10. Secretion of flagellin by the LEE-encoded type III secretion system of enteropathogenic Escherichia coli.

    Science.gov (United States)

    Badea, Luminita; Beatson, Scott A; Kaparakis, Maria; Ferrero, Richard L; Hartland, Elizabeth L

    2009-02-06

    Enteropathogenic Escherichia coli (EPEC) is an attaching and effacing (A/E) pathogen that possesses a type III secretion system (T3SS) encoded within the locus of enterocyte effacement (LEE). The LEE is essential for A/E lesion formation and directs the secretion and translocation of multiple LEE-encoded and non-LEE encoded effector proteins into the cytosol of infected cells. In this study we used proteomics to compare proteins exported to the culture supernatant by wild type EPEC E2348/69, a DeltaespADB mutant and a DeltaescF T3SS mutant. We observed that flagellin was consistently and strongly present in the secretome of wild type EPEC and the DeltaespADB mutant but present only weakly in the secretome of the DeltaescF mutant. Given the ancestral relationship between the flagella export apparatus and virulence associated T3SSs, we investigated whether FliC could utilise the LEE-encoded T3SS for export. In the absence of a functional flagella export apparatus, we showed that FliC could be secreted by the LEE-encoded T3SS and stimulate (Toll-like receptor 5) TLR5 signalling but could not confer motility. Since the secretion of FliC during A/E lesion formation would presumably be disadvantageous for the pathogen, we propose that virulence associated T3SSs and flagella T3SSs have evolved through a system of chaperones and complex regulatory pathways to be functional at different times to ensure that FliC secretion does not occur during T3SS effector translocation.

  11. Prenatal molecular testing for Beckwith-Wiedemann and Silver-Russell syndromes

    DEFF Research Database (Denmark)

    Eggermann, Thomas; Brioude, Frédéric; Russo, Silvia

    2016-01-01

    Beckwith-Wiedemann and Silver-Russell syndromes (BWS/SRS) are two imprinting disorders (IDs) associated with disturbances of the 11p15.5 chromosomal region. In BWS, epimutations and genomic alterations within 11p15.5 are observed in >70% of patients, whereas in SRS they are observed in about 60% ......, the consequences for prenatal genetic testing and counseling and our cumulative experience in dealing with these disorders.European Journal of Human Genetics advance online publication, 28 October 2015; doi:10.1038/ejhg.2015.224....... molecular findings underlying these disorders are a challenge not only for laboratories offering these tests but also for geneticists counseling affected families. The scope of counseling must consider the range of detectable disturbances and their origin, the lack of precise quantitative knowledge...

  12. Synchronization and anti-synchronization coexist in Chen-Lee chaotic systems

    International Nuclear Information System (INIS)

    Chen, J.-H.; Chen, H.-K.; Lin, Y.-K.

    2009-01-01

    This study demonstrates that synchronization and anti-synchronization can coexist in Chen-Lee chaotic systems by direct linear coupling. Based on Lyapunov's direct method, a linear controller was designed to assure that two different types of synchronization can simultaneously be achieved. Further, the hybrid projective synchronization of Chen-Lee chaotic systems was studied using a nonlinear control scheme. The nonlinear controller was designed according to the Lyapunov stability theory to guarantee the hybrid projective synchronization, including synchronization, anti-synchronization, and projective synchronization. Finally, numerical examples are presented in order to illustrate the proposed synchronization approach.

  13. Deterministic and stochastic trends in the Lee-Carter mortality model

    DEFF Research Database (Denmark)

    Callot, Laurent; Haldrup, Niels; Kallestrup-Lamb, Malene

    2015-01-01

    The Lee and Carter (1992) model assumes that the deterministic and stochastic time series dynamics load with identical weights when describing the development of age-specific mortality rates. Effectively this means that the main characteristics of the model simplify to a random walk model with age...... mortality data. We find empirical evidence that this feature of the Lee–Carter model overly restricts the system dynamics and we suggest to separate the deterministic and stochastic time series components at the benefit of improved fit and forecasting performance. In fact, we find that the classical Lee...

  14. Deterministic and stochastic trends in the Lee-Carter mortality model

    DEFF Research Database (Denmark)

    Callot, Laurent; Haldrup, Niels; Kallestrup-Lamb, Malene

    The Lee and Carter (1992) model assumes that the deterministic and stochastic time series dynamics loads with identical weights when describing the development of age specific mortality rates. Effectively this means that the main characteristics of the model simplifies to a random walk model...... that characterizes mortality data. We find empirical evidence that this feature of the Lee-Carter model overly restricts the system dynamics and we suggest to separate the deterministic and stochastic time series components at the benefit of improved fit and forecasting performance. In fact, we find...

  15. What the Butler Saw: Lee Daniels's Studies in Biography and History

    Science.gov (United States)

    Beck, Bernard

    2014-01-01

    The movie "Lee Daniels' The Butler" is an example of a work that is meant not only to entertain but to convey an important attitude and offer important viewpoints. The movie deals with a deep issue in the history of movies and the history of the country: racial inequality. Three issues are discussed in this article: (a) African…

  16. Optimization Evaluation: Lee Chemical Superfund Site, City Of Liberty, Clay County, Missouri

    Science.gov (United States)

    The Lee Chemical Superfund Site (site) is located along Missouri Highway 210 in Liberty, Missouri, approximately 15 miles east of Kansas City, Missouri. Currently, the site is a vacant lot of approximately2.5 acres in a flat alluvial plain.

  17. Forecasting selected specific age mortality rate of Malaysia by using Lee-Carter model

    Science.gov (United States)

    Shukri Kamaruddin, Halim; Ismail, Noriszura

    2018-03-01

    Observing mortality pattern and trend is an important subject for any country to maintain a good social-economy in the next projection years. The declining in mortality trend gives a good impression of what a government has done towards macro citizen in one nation. Selecting a particular mortality model can be a tricky based on the approached method adapting. Lee-Carter model is adapted because of its simplicity and reliability of the outcome results with approach of regression. Implementation of Lee-Carter in finding a fitted model and hence its projection has been used worldwide in most of mortality research in developed countries. This paper studies the mortality pattern of Malaysia in the past by using original model of Lee-Carter (1992) and hence its cross-sectional observation for a single age. The data is indexed by age of death and year of death from 1984 to 2012, in which are supplied by Department of Statistics Malaysia. The results are modelled by using RStudio and the keen analysis will focus on the trend and projection of mortality rate and age specific mortality rate in the future. This paper can be extended to different variants extensions of Lee-Carter or any stochastic mortality tool by using Malaysia mortality experience as a centre of the main issue.

  18. INCA Modelling of the Lee System: strategies for the reduction of nitrogen loads

    Science.gov (United States)

    Flynn, N. J.; Paddison, T.; Whitehead, P. G.

    The Integrated Nitrogen Catchment model (INCA) was applied successfully to simulate nitrogen concentrations in the River Lee, a northern tributary of the River Thames for 1995-1999. Leaching from urban and agricultural areas was found to control nitrogen dynamics in reaches unaffected by effluent discharges and abstractions; the occurrence of minimal flows resulted in an upward trend in nitrate concentration. Sewage treatment works (STW) discharging into the River Lee raised nitrate concentrations substantially, a problem which was compounded by abstractions in the Lower Lee. The average concentration of nitrate (NO3) for the simulation period 1995-96 was 7.87 mg N l-1. Ammonium (NH4) concentrations were simulated less successfully. However, concentrations of ammonium rarely rose to levels which would be of environmental concern. Scenarios were run through INCA to assess strategies for the reduction of nitrate concentrations in the catchment. The conversion of arable land to ungrazed vegetation or to woodland would reduce nitrate concentrations substantially, whilst inclusion of riparian buffer strips would be unsuccessful in reducing nitrate loading. A 50% reduction in nitrate loading from Luton STW would result in a fall of up to 5 mg N l-1 in the reach directly affected (concentrations fell from maxima of 13 to 8 mg N l-1 , nearly a 40 % reduction), whilst a 20% reduction in abstractions would reduce maximum peaks in concentration in the lower Lee by up to 4 mg l-1 (from 17 to 13 mg N l-1, nearly a 25 % reduction),.

  19. Servicing the first web server - Tim Berners-Lee's NeXT

    CERN Multimedia

    unknown, Association aBCM

    2009-01-01

    In August 2009 a team from the Association aBCM in Lausanne came to CERN to give the world's first web server a health check under the watchful eye of web pioneer Robert Cailliau. They took an image of the hard drive at this time, copies of which were given to Robert Cailliau and Tim Berners-Lee.

  20. Charcot, Mitchell and Lees: neurology free thinkers and their experiences of psychoactive drugs

    Directory of Open Access Journals (Sweden)

    Hélio A. G. Teive

    Full Text Available ABSTRACT Three world-famous neurologists, Charcot and Mitchell, in the 19th century, and Lees, in this century, all of whom had great scientific curiosity, experimented with the psychoactive drugs hashish, mescal and yagé, respectively, in an attempt to increase their knowledge of neurological diseases and how the brain works.

  1. Yang-Lee edge singularity on a class of tree-like lattices

    Energy Technology Data Exchange (ETDEWEB)

    Knezevic, Milan; Elezovic-Hadzic, Suncica [Faculty of Physics, University of Belgrade, Belgrade (Yugoslavia)

    1997-03-21

    The density of zeros of the partition function of the Ising model on a class of tree-like lattices is studied. An exact closed-form expression for the pertinent critical exponents is derived by using a couple of recursion relations which have a singular behaviour near the Yang-Lee edge. (author)

  2. Fighting with Reality: Considering Mark Johnson's Pragmatic Realism through Bruce Lee's Jeet Kune Do Method

    Science.gov (United States)

    Miller, Alexander David

    2015-01-01

    This dissertation considers the supportive and complementary relation between Mark Johnson's embodied realism and Bruce Lee's Jeet Kune Do as a philosophical practice. In exploring this relationship, the emphasis on one's embodiment condition and its relationship with metaphor and self-expression are the primary focus. First, this work involves…

  3. Lee-side flow structures of very low aspect ratio cruciform wing–body configurations

    CSIR Research Space (South Africa)

    Tuling, S

    2013-12-01

    Full Text Available OF SPACECRAFT AND ROCKETS Vol. 50, No. 6, November–December 2013 Lee-Side Flow Structures of Very Low Aspect Ratio Cruciform Wing–Body Configurations S. Tuling∗ Council for Scientific and Industrial Research, Pretoria 0001, South Africa L. Dala...

  4. Thomas George Lee - Implantation and early development of North American rodents

    DEFF Research Database (Denmark)

    Carter, Anthony Michael

    2011-01-01

    A century ago Thomas G. Lee amassed an unparalleled collection of developmental series of North American rodents such as the thirteen-lined ground squirrel, the Plains pocket gopher and Merriam's kangaroo rat. He was the first to describe the initial attachment of the squirrel blastocyst...

  5. Co-ordinate single-cell expression of LEE4- and LEE5-encoded proteins of Escherichia coli O157:H7.

    Science.gov (United States)

    Roe, Andrew J; Naylor, Stuart W; Spears, Kevin J; Yull, Helen M; Dransfield, Tracy A; Oxford, Matthew; McKendrick, Iain J; Porter, Megan; Woodward, Martin J; Smith, David G E; Gally, David L

    2004-10-01

    Escherichia coli O157:H7 is a zoonotic pathogen that can express a type III secretion system (TTSS) considered important for colonization and persistence in ruminants. E. coli O157:H7 strains have been shown to vary markedly in levels of protein secreted using the TTSS and this study has confirmed that a high secretion phenotype is more prevalent among isolates associated with human disease than isolates shed by healthy cattle. The variation in secretion levels is a consequence of heterogeneous expression, being dependent on the proportion of bacteria in a population that are actively engaged in protein secretion. This was demonstrated by indirect immunofluorescence and eGFP fusions that examined the expression of locus of enterocyte effacement (LEE)-encoded factors in individual bacteria. In liquid media, the expression of EspA, tir::egfp, intimin, but not map::egfp were co-ordinated in a subpopulation of bacteria. In contrast to E. coli O157:H7, expression of tir::egfp in EPEC E2348/69 was equivalent in all bacteria although the same fusion exhibited variable expression when transformed into an E. coli O157:H7 background. An E. coli O157:H7 strain deleted for the LEE demonstrated weak but variable expression of tir::egfp indicating that the elements controlling the heterogeneous expression lie outside the LEE. The research also demonstrated the rapid induction of tir::egfp and map::egfp on contact with bovine epithelial cells. This control in E. coli O157:H7 may be required to limit exposure of key surface antigens, EspA, Tir and intimin during colonization of cattle but allow their rapid production on contact with bovine gastrointestinal epithelium at the terminal rectum.

  6. Cecilia Payne-Gaposchkin, Henry Norris Russell Lecture: Fifty Years of Novae

    Science.gov (United States)

    Burbidge, E. M.

    1999-05-01

    It is easy to pick out my most memorable meeting of the AAS: the 149th meeting held in January, 1977, and hosted by the University of Hawaii, in Honolulu, HI. It was the meeting at which two traditions of the Society were broken, and we moved into the era of equal opportunity for women astronomers. Cecilia Payne-Gaposchkin received the highest award of the AAS: the Henry Norris Russell Lectureship. This award had never before been available to women, otherwise Cecilia would, years earlier, have been honored for the many achievements in her lifetime of renowned astronomical research. And I, the first woman to be elected President of the AAS, had the honor of presenting the illuminated scroll to Cecilia, and of introducing her on the platform where she delivered the Henry Norris Russell Prize Lecture, entitled ``Fifty Years of Novae"(1) . Cecilia opened by comparing the experience of young and old scientists in achieving exciting results from their research, and then led us through the history of the discoveries of and about some famous novae. She described the physical picture that emerged from studies of their light curves, their spectra, and the discovery of their binary nature. Three important tables were included, listing data on cataclysmic binaries (dwarf novae) and their link to the nova phenomenon in general. She recalled that she and Sergei Gaposchkin had hesitated between the names catastrophic and cataclysmic for the dwarf novae, and decided on the latter, from the dictionary definitions of those two terms: ``a cataclysm is a great and general flood" while a catastrophe ``is a final event". The nova phenomenon is recurrent, as are the dwarf novae, and both involve an outpouring of a flood of energy. She concluded by describing her 50 years' experience with novae as presenting ``the contemporary portrait of a nova", rather than a final picture, and by forecasting that the next 50 years of discovering and studying novae will be as full of surprises as the

  7. The medical theory of Lee Je-ma and its character

    Directory of Open Access Journals (Sweden)

    LEE Kyung-Lock

    2005-12-01

    Full Text Available Lee Je-ma(李濟馬, 1837-1900 was a prominent scholar as well as an Korean physician He classified every people into four distinctive types: greater yang[tai yang] person, lesser yin[shao yin] person greater yin[tai yin] person, lesser yin[shao yin] person. This theory would dictate proper treatment for each type in accordance with individual differences of physical and temperament features Using these four types he created The Medical Science of Four Types(四象體質論.This article is intended to look into the connection between Lee Je-Ma's 'The Medical Science of Four Types' and 'The Modern' with organizing his ideas about the human body and the human being. Through The Modern, the theory of human being(人間觀 underwent a complete change. Human being in The Premodern, which was determined by sex, age and social status has been changed to the individual human being, which is featured by equality. Lee Je-Ma's medical theory of The Medical Science of Four Types would be analyzed as follow. His concept of human body(人體論 is oriented toward observable objectivity. But on the other hand, it still remains transcendent status of medical science, which is subordinated by philosophy According to Lee Je-Ma's theory of human being human is an equal individual in a modern way of thinking not as a part of hierarchical group. But on the other hand, it still remains incomplete from getting rid of morality aspect that includes virtue and vice in the concept of human body.The common factors in Lee Je-Ma's ideas about the human body and the human being is 'Dualism of mind and body(心身二元論' that means all kinds of status and results depends on each individual. As is stated above, Lee Je-Ma's medical theory has many aspects of The Modern and it proves that Korean traditional medicine could be modernized by itself.

  8. Joseph A. Burton Forum Award Talk: Remembering our Humanity: the deep impact of the Russell-Einstein Manifesto

    Science.gov (United States)

    Lewis, Patricia M.

    2009-05-01

    ``There lies before us, if we choose, continual progress in happiness, knowledge, and wisdom. Shall we, instead, choose death, because we cannot forget our quarrels? We appeal as human beings to human beings: Remember your humanity, and forget the rest.'' Days before his death, Albert Einstein joined Bertrand Russell and other notable scientists and philosophers in issuing a statement calling for the abolition of war and for governments to ``find peaceful means for the settlement of all matters of dispute between them." As a first step, they called for the renunciation of nuclear weapons. The initiative led to the establishment of the Pugwash Conferences on Science and World Affairs, which bring together influential scholars and public figures concerned with reducing the danger of armed conflict and seeking cooperative solutions for global problems. The Russell-Einstein Manifesto has had a major impact on the way in which people discuss the issues of peace and war. The paper traces the growing awareness of the meaning of war, ways in which violent conflict can be prevented, particularly in the nuclear age, and the humanitarian imperative for so doing. From the Russell-Einstein Manifesto, London, 9 July 1955, signed also by Max Born, Percy W. Bridgman, Leopold Infeld, Frederic Joliot-Curie, Herman J. Muller, Linus Pauling, Cecil F. Powell, Joseph Rotblat and Hideki Yukawa

  9. The prominent absence of Alfred Russel Wallace at the Darwin anniversaries in Germany in 1909, 1959 and 2009.

    Science.gov (United States)

    Hossfeld, Uwe; Olsson, Lennart

    2013-12-01

    It is well known that the contribution of Alfred Russell Wallace (1823-1913) to the development of the "Darwinian" principle of natural selection has often been neglected. Here we focus on how the three anniversaries to celebrate the origin of the Darwin-Wallace theory in Germany in 1909, in 1959 in the divided country, as well as in 2009, have represented Charles Robert Darwin's and Alfred Russell Wallace's contributions. We have analyzed books and proceedings volumes related to these anniversaries, and the main result is that Wallace was almost always ignored, or only mentioned in passing. In 1909, Ernst Haeckel gave a talk in Jena, later published under the title The worldview of Darwin and Lamarck (Das Weltbild von Darwin und Lamarck), but not as the Darwin-Wallace concept. Haeckel mentions Wallace only once. In two important proceedings volumes from the 1959 anniversaries, Wallace was ignored. The only fair treatment of Wallace is given in another book, a collection of documents edited by Gerhard Heberer, for which the author selected nine key documents and reprinted excerpts (1959). Three of them were articles by Wallace, including the Sarawak- and Ternate-papers of 1855 and 1858, respectively. An analysis of the dominant themes during the celebrations of 2009 shows that none of the six topics had much to do with Wallace and his work. Thus, the tendency to exclude Alfred Russell Wallace is an international phenomenon, and largely attributable to the "Darwin industry".

  10. The ornithologist Alfred Russel Wallace and the controversy surrounding the dinosaurian origin of birds.

    Science.gov (United States)

    Ibrahim, Nizar; Kutschera, Ulrich

    2013-12-01

    Over many years of his life, the British naturalist Alfred Russel Wallace (1823-1913) explored the tropical forests of Malaysia, collecting numerous specimens, including hundreds of birds, many of them new to science. Subsequently, Wallace published a series of papers on systematic ornithology, and discovered a new species on top of a volcano on Ternate, where he wrote, in 1858, his famous essay on natural selection. Based on this hands-on experience, and an analysis of an Archaeopteryx fossil, Wallace suggested that birds may have descended from dinosaurian ancestors. Here, we describe the "dinosaur-bird hypothesis" that originated with the work of Thomas H. Huxley (1825-1895). We present the strong evidence linking theropod dinosaurs to birds, and briefly outline the long and ongoing controversy around this concept. Dinosaurs preserving plumage, nesting sites and trace fossils provide overwhelming evidence for the dinosaurian origin of birds. Based on these recent findings of paleontological research, we conclude that extant birds indeed descended, with some modifications, from small, Mesozoic theropod dinosaurs. In the light of Wallace's view of bird origins, we critically evaluate recent opposing views to this idea, including Ernst Mayr's (1904-2005) arguments against the "dinosaur-bird hypothesis", and document that this famous ornithologist was not correct in his assessment of this important aspect of vertebrate evolution.

  11. The mine and the furnace: Francis Bacon, Thomas Russell, and early Stuart mining culture.

    Science.gov (United States)

    Pastorino, Cesare

    2009-01-01

    Notwithstanding Francis Bacon's praise for the philosophical role of the mechanical arts, historians have often downplayed Bacon's connections with actual artisans and entrepreneurs. Addressing the specific context of mining culture, this study proposes a rather different picture. The analysis of a famous mining metaphor in The Advancement of Learning shows us how Bacon's project of reform of knowledge could find an apt correspondence in civic and entrepreneurial values of his time. Also, Bacon had interesting and so far unexplored links with the early modern English mining enterprises, like the Company of Mineral and Battery Works, ofwhich he was a shareholder. Moreover, Bacon's notes in a private notebook, Commentarius Solutus, and records of patents of invention, allow us to start grasping Bacon's connections with the metallurgist and entrepreneur Thomas Russell. Lastly, this paper argues that, to fully understand Bacon's links with the world of Stuart technicians and entrepreneurs, it is necessary to consider a different and insufficiently studied aspect of Bacon's interests, namely his work as patents referee while a Commissioner of Suits.

  12. Systemic and maxillofacial characteristics of 11 Japanese children with Russell-Silver syndrome.

    Science.gov (United States)

    Sato, Chiemi; Ogawa, Takuya; Tsuge, Risa; Shiga, Momotoshi; Tsuji, Michiko; Baba, Yoshiyuki; Kosaki, Kenjiro; Moriyama, Keiji

    2016-09-01

    Russell-Silver syndrome (RSS) is a congenital anomaly characterized by intrauterine and postnatal growth retardation, typical facial features, fifth-finger clinodactyly, and skeletal asymmetry. Although data on intrauterine and postnatal growth retardation have been reported, there are few reports concerning the typical maxillofacial morphology in individuals with RSS. The aim of this study was to describe the details of this systemic condition and to characterize maxillofacial morphology based on cephalograms in 11 Japanese patients (age range, 3.9-12.0 years) with RSS. All 11 individuals had intrauterine and postnatal growth retardation. In addition, most showed mandibular retrognathia and relative macrocephaly. Lateral cephalogram measurements showed that mandibular retrognathia resulted from short mandibular body length, whereas the depth of the cranial base was close to normal. Although asymmetry of hand, foot, and limb length were present in most individuals, obvious facial asymmetry was not common. Differences between left and right skeletal and dental age were not observed, indicating that children with RSS might show asymmetry because of quantitative differences in skeletal growth rather than delayed growth rate. Our findings not only provide important information about the maxillofacial characteristics of RSS, but also help to clarify the association between these characteristics and genetics, which will add to the body of information on clinical symptoms. © 2016 Japanese Teratology Society.

  13. Silver-Russell Syndrome and Beckwith-Wiedemann Syndrome: Opposite Phenotypes with Heterogeneous Molecular Etiology

    Science.gov (United States)

    Õunap, Katrin

    2016-01-01

    Silver-Russell syndrome (SRS) and Beckwith-Wiedemann syndrome (BWS) are 2 clinically opposite growth-affecting disorders belonging to the group of congenital imprinting disorders. The expression of both syndromes usually depends on the parental origin of the chromosome in which the imprinted genes reside. SRS is characterized by severe intrauterine and postnatal growth retardation with various additional clinical features such as hemihypertrophy, relative macrocephaly, fifth finger clinodactyly, and triangular facies. BWS is an overgrowth syndrome with many additional clinical features such as macroglossia, organomegaly, and an increased risk of childhood tumors. Both SRS and BWS are clinically and genetically heterogeneous, and for clinical diagnosis, different diagnostic scoring systems have been developed. Six diagnostic scoring systems for SRS and 4 for BWS have been previously published. However, neither syndrome has common consensus diagnostic criteria yet. Most cases of SRS and BWS are associated with opposite epigenetic or genetic abnormalities in the 11p15 chromosomal region leading to opposite imbalances in the expression of imprinted genes. SRS is also caused by maternal uniparental disomy 7, which is usually identified in 5-10% of the cases, and is therefore the first imprinting disorder that affects 2 different chromosomes. In this review, we describe in detail the clinical diagnostic criteria and scoring systems as well as molecular causes in both SRS and BWS. PMID:27587987

  14. A rare case of Silver–Russell syndrome associated with growth hormone deficiency and urogenital abnormalities

    Science.gov (United States)

    Prasad, Namburi Rajendra; Reddy, Ponnala Amaresh; Karthik, T. S.; Chakravarthy, Mithun; Ahmed, Faizal

    2012-01-01

    Introduction: Silver–Russell syndrome (SRS) is a very rare genetic disorder. This is usually characterized by asymmetry in the size of the two halves or other parts of the body. Background: We are presenting a case of SRS with growth hormone (GH) deficiency and urogenital abnormalities. Case Report: A 15-year-old boy a product of non-consanguineous marriage brought with a history of short stature and poor development of secondary sexual characters. There were no adverse perinatal events, but weighed 1500 g (hemihypertrophy on the right side. His height was 119 cm (<3rdcentile) and weight was 18 kg which were low (<3rdcentile) as per his age. He was biochemically euthyroid and GH stimulation testing with clonidine (0.15 mg/m2) showed low GH levels at 30′, 60′, and 90′ were 1.7, 1.6, and 1.1ng/ml, respectively. On micturatingcystourethrogram, grade V complex was noted on the right side. Dimercaptosuccinic acid (DMSA) showed normal functioning kidneys. He was started on recombinant GH with a height velocity of 10 cm/year. Conclusion: Urogenital abnormalities are rare but well described anomalies associated with SRS, and all cases have to be screened for them. GH deficiency is not uncommon in SRS, and GH treatment proves to be beneficial. PMID:23565409

  15. Alfred Russel Wallace and the destruction of island life: the Iguana tragedy.

    Science.gov (United States)

    Kutschera, Ulrich; Kleinhans, Simon

    2013-12-01

    The Galápagos Islands (Ecuador) are usually associated with the explorations and theoretical deductions of Charles Robert Darwin (1809-1882), but Alfred Russel Wallace (1823-1913) also investigated these islands and published several reports on the living world of this unique archipelago. In contrast to Darwin, Wallace described the destruction of natural ecosystems by humans and foresaw the resulting extinction of species. Here, we outline two case studies pertinent to Wallace's prediction. First, we summarize the behavior of the predator-naive marine iguanas (Amblyrhynchus cristatus) on the Galápagos Islands, which are threatened by feral dogs and cats imported by humans. We also describe the unique life cycle of the spiny-tailed iguana (Ctenosaura bakeri) from the island of Utila (Honduras), a rare species whose populations are declining because of habitat destructions. In contrast to these threatened, endemic island species, the Green iguana (Iguana iguana) is still widely distributed, although, as a result of de-forestation, in some areas of South America local populations have disappeared. We conclude that Wallace was correct in his prediction that, because of human activities, numerous species of animals and plants will be driven to extinction, notably on islands.

  16. Diagnosis and management of Silver-Russell syndrome: first international consensus statement.

    Science.gov (United States)

    Wakeling, Emma L; Brioude, Frédéric; Lokulo-Sodipe, Oluwakemi; O'Connell, Susan M; Salem, Jennifer; Bliek, Jet; Canton, Ana P M; Chrzanowska, Krystyna H; Davies, Justin H; Dias, Renuka P; Dubern, Béatrice; Elbracht, Miriam; Giabicani, Eloise; Grimberg, Adda; Grønskov, Karen; Hokken-Koelega, Anita C S; Jorge, Alexander A; Kagami, Masayo; Linglart, Agnes; Maghnie, Mohamad; Mohnike, Klaus; Monk, David; Moore, Gudrun E; Murray, Philip G; Ogata, Tsutomu; Petit, Isabelle Oliver; Russo, Silvia; Said, Edith; Toumba, Meropi; Tümer, Zeynep; Binder, Gerhard; Eggermann, Thomas; Harbison, Madeleine D; Temple, I Karen; Mackay, Deborah J G; Netchine, Irène

    2017-02-01

    This Consensus Statement summarizes recommendations for clinical diagnosis, investigation and management of patients with Silver-Russell syndrome (SRS), an imprinting disorder that causes prenatal and postnatal growth retardation. Considerable overlap exists between the care of individuals born small for gestational age and those with SRS. However, many specific management issues exist and evidence from controlled trials remains limited. SRS is primarily a clinical diagnosis; however, molecular testing enables confirmation of the clinical diagnosis and defines the subtype. A 'normal' result from a molecular test does not exclude the diagnosis of SRS. The management of children with SRS requires an experienced, multidisciplinary approach. Specific issues include growth failure, severe feeding difficulties, gastrointestinal problems, hypoglycaemia, body asymmetry, scoliosis, motor and speech delay and psychosocial challenges. An early emphasis on adequate nutritional status is important, with awareness that rapid postnatal weight gain might lead to subsequent increased risk of metabolic disorders. The benefits of treating patients with SRS with growth hormone include improved body composition, motor development and appetite, reduced risk of hypoglycaemia and increased height. Clinicians should be aware of possible premature adrenarche, fairly early and rapid central puberty and insulin resistance. Treatment with gonadotropin-releasing hormone analogues can delay progression of central puberty and preserve adult height potential. Long-term follow up is essential to determine the natural history and optimal management in adulthood.

  17. Alfred Russel Wallace's medical libertarianism: state medicine, human progress, and evolutionary purpose.

    Science.gov (United States)

    Flannery, Michael A

    2015-01-01

    Alfred Russel Wallace (1823-1913), naturalist and explorer of South America and the Malay Archipelago, secured his place in history by independently discovering the theory of natural selection. His letter outlining the theory was sent from Ternate in eastern Indonesia and received at Down House, according to Charles Darwin (1809-82), on June 18, 1858, prompting the now-famed evolutionist to rush his languishing manuscript to press. Wallace's contributions to evolutionary biology, biogeography, and anthropology are well known, but his medical views have received far less attention. Within the context of a strident populist antivaccination movement and an ominous elitist eugenics campaign, Wallace took his stand, which revealed itself in a libertarianism that defended traditional socialist constituencies (the working poor, the lumpenproletariat, and feminist reformers) against state-mandated medical interventions. Rather than viewing Wallace as a heterodox contrarian, this article argues that his positions were logical outgrowths of his medical libertarianism and evolutionary and social theories. © The Author 2013. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. The three Rs of Russell & Burch and the testing of biological products.

    Science.gov (United States)

    Balls, M; Straughan, D W

    1996-01-01

    The principles of humane animal experimentation proposed by Russell & Burch (1959), namely, replacement, reduction, and refinement, are now commonly known as the Three Rs. These principles are clearly embodied in Article 7 of Directive 86/609/EEC. It is instructive, therefore, to consider the priority currently attached to compliance with these principles and to the Directive in the development and control of biological products. Specific comments are made on the need for the application of the Three Rs in relation to the testing of human diphtheria and tetanus vaccines, human pertussis vaccine, inactivated veterinary Gumboro vaccine, veterinary Newcastle disease vaccine, veterinary clostridial vaccines and botulinum toxin. We pose three questions: a. Are the minimum numbers of animals already being used in this area? b. Is any unnecessary pain, suffering, distress or lasting harm being inflicted on the animals used? and c. What could and should be done about any shortcomings in current practice? Finally, the role of ECVAM in the promotion of the Three Rs within the European Union will be reviewed.

  19. Sindrome de russel tumor diencefálico em uma criança

    Directory of Open Access Journals (Sweden)

    Luiz A. C. Roxo da Motta

    1990-03-01

    Full Text Available Apresenta-se o caso de criança do sexo masculino com síndrome de Russel devida a astrocitoma pilocítico localizado na região diencefálica. O diagnóstico foi realizado aos 16 meses de idade, mas sua sintomatologia se iniciou aos 4 meses, com emagrecimento progressivo. À internação apresentava-se com peso de 6150g e 74cm de estatura, emaciada, sem panículo adiposo, irritadica e com sinais de hipertensão intracraniana. Existia estrabismo convergente, nistagmo vertical do olho esquerdo e papiledema bilateral. Os reflexos tendinosos eram exaltados e tinha tetraparesia espástica. A avaliação endócrina demonstrou aumento basal do GH (23 ng/ml, do TSH (6,2 mUI/l e da prolactina (26 ng/ml. Os dois primeiros hormônios não responderam ao teste agudo com o TRH, enquanto a prolactina teve resposta pobre. Foi submetida a radioterapia com acelerador linear (dose total de 4000 rads e a cirurgia, na qual não se conseguiu extirpar todo o tumor, devido a seu tamanho. Nove meses após, a criança encontra-se bem, com apreciável ganho ponderai (2500g.

  20. Water quality and ecology of the River Lee: mass balance and a review of temporal and spatial data

    Directory of Open Access Journals (Sweden)

    D. L. Snook

    2004-01-01

    Full Text Available A regional overview of the water quality and ecology of the River Lee catchment is presented. Specifically, data describing the chemical, microbiological and macrobiological water quality and fisheries communities have been analysed, based on a division into river, sewage treatment works, fish-farm, lake and industrial samples. Nutrient enrichment and the highest concentrations of metals and micro-organics were found in the urbanised, lower reaches of the Lee and in the Lee Navigation. Average annual concentrations of metals were generally within environmental quality standards although, on many occasions, concentrations of cadmium, copper, lead, mercury and zinc were in excess of the standards. Various organic substances (used as herbicides, fungicides, insecticides, chlorination by-products and industrial solvents were widely detected in the Lee system. Concentrations of ten micro-organic substances were observed in excess of their environmental quality standards, though not in terms of annual averages. Sewage treatment works were the principal point source input of nutrients, metals and micro-organic determinands to the catchment. Diffuse nitrogen sources contributed approximately 60% and 27% of the in-stream load in the upper and lower Lee respectively, whereas approximately 60% and 20% of the in-stream phosphorus load was derived from diffuse sources in the upper and lower Lee. For metals, the most significant source was the urban runoff from North London. In reaches less affected by effluent discharges, diffuse runoff from urban and agricultural areas dominated trends. High microbiological content, observed in the River Lee particularly in urbanised reaches, was far in excess of the EC Bathing Water Directive standards. Water quality issues and degraded habitat in the lower reaches of the Lee has led to impoverished aquatic fauna but, within the mid-catchment reaches and upper agricultural tributaries, less nutrient enrichment and channel

  1. Parametric study of the fractional-order Chen-Lee system

    Energy Technology Data Exchange (ETDEWEB)

    Tam, L.M. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau (China)], E-mail: fstlmt@umac.mo; Tou, W.M.S. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Tomas Pereira S.J., Taipa, Macau (China)

    2008-08-15

    The dynamics of fractional-order systems have attracted a great deal of attention in recent years. In this paper, the effects of parameter changes on the dynamics of the fractional-order Chen-Lee system were studied numerically. The parameter ranges used were relatively broad. The order used for the system was fixed at 2.7 (q{sub 1} = q{sub 2} = q{sub 3} = 0.9). The system displays rich dynamic behaviors, such as a fixed point, periodic motion (including period-3 motion), chaotic motion, and transient chaos. The chaotic motion identified was validated by the confirmation of a positive Lyapunov exponent. Period-doubling routes to chaos in the fractional-order Chen-Lee system were also found.

  2. Lee Wen: Lucid Dreams In the Reverie of the Real

    OpenAIRE

    Mokhtari, Sylvie

    2012-01-01

    Cette monographie rétrospective réunit la somme des travaux, associant depuis vingt ans performances et installations, de l’artiste singapourien Lee Wen (né en 1957). Ambigu et très expressive, son activité est relatée de manière biographique sous la plume de Khairuddin Hori (« If you can’t think because you can’t chew, try a banana », pp.9-19). Textes de et sur Lee Wen, témoignages, documents et travaux viennent ensuite généreusement nourrir la publication. Des Anthropométries d’Yves Klein, ...

  3. The Brain Dead Patient Is Still Sentient: A Further Reply to Patrick Lee and Germain Grisez.

    Science.gov (United States)

    Austriaco, Nicanor Pier Giorgio

    2016-06-01

    Patrick Lee and Germain Grisez have argued that the total brain dead patient is still dead because the integrated entity that remains is not even an animal, not only because he is not sentient but also, and more importantly, because he has lost the radical capacity for sentience. In this essay, written from within and as a contribution to the Catholic philosophical tradition, I respond to Lee and Grisez's argument by proposing that the brain dead patient is still sentient because an animal with an intact but severed spinal cord can still perceive and respond to external stimuli. The brain dead patient is an unconscious sentient organism. © The Author 2016. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE Pathogenicity Island in Enteropathogenic Escherichia coli

    Directory of Open Access Journals (Sweden)

    Hervé Leh

    2017-08-01

    Full Text Available In enteropathogenic Escherichia coli (EPEC, the locus of enterocyte effacement (LEE encodes a type 3 secretion system (T3SS essential for pathogenesis. This pathogenicity island comprises five major operons (LEE1 to LEE5, with the LEE5 operon encoding T3SS effectors involved in the intimate adherence of bacteria to enterocytes. The first operon, LEE1, encodes Ler (LEE-encoded regulator, an H-NS (nucleoid structuring protein paralog that alleviates the LEE H-NS silencing. We observed that the LEE5 and LEE1 promoters present a bimodal expression pattern, depending on environmental stimuli. One key regulator of bimodal LEE1 and LEE5 expression is ler expression, which fluctuates in response to different growth conditions. Under conditions in vitro considered to be equivalent to nonoptimal conditions for virulence, the opposing regulatory effects of H-NS and Ler can lead to the emergence of two bacterial subpopulations. H-NS and Ler share nucleation binding sites in the LEE5 promoter region, but H-NS binding results in local DNA structural modifications distinct from those generated through Ler binding, at least in vitro. Thus, we show how two nucleoid-binding proteins can contribute to the epigenetic regulation of bacterial virulence and lead to opposing bacterial fates. This finding implicates for the first time bacterial-chromatin structural proteins in the bimodal regulation of gene expression.

  5. Grape marc, wine lees and deposit of the must: How to manage oenological by-products?

    OpenAIRE

    Lempereur Valérie; Penavayre Sophie

    2014-01-01

    Winemaking produces solid (grape marc) and liquid (wine lees and deposit of the must) wastes named “oenological by-products”, which, according to European regulations, must be eliminated following the environmental regulatory requirement [1]. In France, these European regulations forced wine growers, until the 2013/2014 campaign, to deliver all by-products to wine distilleries. This French obligation is known as the “prestation vinique” [2, 3]. Following the Common Market Organisation wine re...

  6. LEE: Light‐Weight Energy‐Efficient encryption algorithm for sensor networks

    OpenAIRE

    Komninos, N.; Soroush, H.; Salajegheh, M.

    2007-01-01

    Data confidentiality in wireless sensor networks is mainly achieved by RC5 and Skipjack encryption algorithms. However, both algorithms have their weaknesses, for example RC5 supports variable-bit rotations, which are computationally expensive operations and Skipjack uses a key length of 80-bits, which is subject to brute force attack. In this paper we introduce a light-weight energy- fficient encryption-algorithm (LEE) for tiny embedded devices, such as sensor network nodes. We present exper...

  7. Nobelist TD LEE Scientist Cooperation Network and Scientist Innovation Ability Model

    OpenAIRE

    Fang, Jin-Qing; Liu, Qiang

    2013-01-01

    Nobelist TD Lee scientist cooperation network (TDLSCN) and their innovation ability are studied. It is found that the TDLSCN not only has the common topological properties both of scale-free and small-world for a general scientist cooperation networks, but also appears the creation multiple-peak phenomenon for number of published paper with year evolution, which become Nobelist TD Lee’s significant mark distinguished from other scientists. This new phenomenon has not been revealed in the scie...

  8. Becoming an International Scientist in South Korea: Ho Wang Lee's Research Activity about Epidemic Hemorrhagic Fever.

    Science.gov (United States)

    Shin, Miyoung

    2017-04-01

    In the 1960-70s, South Korea was still in the position of a science latecomer. Although the scientific research environment in South Korea at that time was insufficient, there was a scientist who achieved outcomes that could be recognized internationally while acting in South Korea. He was Ho Wang Lee(1928~ ) who found Hantann Virus that causes epidemic hemorrhagic fever for the first time in the world. It became a clue to identify causative viruses of hemorrhagic diseases that were scattered here and there throughout the world. In addition, these outcomes put Ho Wang Lee on the global center of research into epidemic hemorrhagic fever. This paper examines how a Korean scientist who was in the periphery of virology could go into the central area of virology. Also this article shows the process through which the virus found by Ho Wang Lee was registered with the international academia and he proceeded with follow-up research based on this progress to reach the level at which he generalized epidemic hemorrhagic fever related studies throughout the world. While he was conducting the studies, experimental methods that he had never experienced encountered him as new difficulties. He tried to solve the new difficulties faced in his changed status through devices of cooperation and connection. Ho Wang Lee's growth as a researcher can be seen as well as a view of a researcher that grew from a regional level to an international level and could advance from the area of non-mainstream into the mainstream. This analytic tool is meaningful in that it can be another method of examining the growth process of scientists in South Korea or developing countries.

  9. Outlining the influence of non-conventional yeasts in wine ageing over lees.

    Science.gov (United States)

    Belda, Ignacio; Navascués, Eva; Marquina, Domingo; Santos, Antonio; Calderón, Fernando; Benito, Santiago

    2016-07-01

    During the last decade, the use of innovative yeast cultures of both Saccharomyces cerevisiae and non-Saccharomyces yeasts as alternative tools to manage the winemaking process have turned the oenology industry. Although the contribution of different yeast species to wine quality during fermentation is increasingly understood, information about their role in wine ageing over lees is really scarce. This work aims to analyse the incidence of three non-Saccharomyces yeast species of oenological interest (Torulaspora delbrueckii, Lachancea thermotolerans and Metschnikowia pulcherrima) and of a commercial mannoprotein-overproducer S. cerevisiae strain compared with a conventional industrial yeast strain during wine ageing over lees. To evaluate their incidence in mouthfeel properties of wine after 4 months of ageing, the mannoprotein content of wines was evaluated, together with other wine analytic parameters, such as colour and aroma, biogenic amines and amino acids profile. Some differences among the studied parameters were observed during the study, especially regarding the mannoprotein concentration of wines. Our results suggest that the use of T. delbrueckii lees in wine ageing is a useful tool for the improvement of overall wine quality by notably increasing mannoproteins, reaching values higher than obtained using a S. cerevisiae overproducer strain. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  10. An unusual feature associated with LEE1 P1 promoters in enteropathogenic Escherichia coli (EPEC).

    Science.gov (United States)

    Jeong, Jae-Ho; Kim, Hyun-Ju; Kim, Kun-Hee; Shin, Minsang; Hong, Yeongjin; Rhee, Joon Haeng; Schneider, Thomas D; Choy, Hyon E

    2012-02-01

    Transcription start points in bacteria are influenced by the nature of the RNA polymerase·promoter interaction. For Escherichia coli RNA polymerase holoenzyme containing σ70, it is presumed that specific sequence in one or more of the -10, extended -10 and -35 elements of the promoter guides the RNAP to select the cognate start point. Here, we investigated the promoter driving expression of the LEE1 operon in enteropathogenic E. coli and found two promoters separated by 10 bp, LEE1 P1A (+1) and LEE1 P1B (+10) using various in vitro biochemical tools. A unique feature of P1B was the presence of multiple transcription starts from five neighbouring As at the initial transcribed region. The multiple products did not arise from stuttering synthesis. Analytical software based on information theory was employed to determine promoter elements. The concentration of the NTP pool altered the preferred transcription start points, albeit the underlying mechanism is elusive. Under in vivo conditions, dominant P1B, but not P1A, was subject to regulation by IHF. © 2012 Blackwell Publishing Ltd.

  11. Observation of Mountain Lee Waves with MODIS NIR Column Water Vapor

    Science.gov (United States)

    Lyapustin, A.; Alexander, M. J.; Ott, L.; Molod, A.; Holben, B.; Susskind, J.; Wang, Y.

    2014-01-01

    Mountain lee waves have been previously observed in data from the Moderate Resolution Imaging Spectroradiometer (MODIS) "water vapor" 6.7 micrometers channel which has a typical peak sensitivity at 550 hPa in the free troposphere. This paper reports the first observation of mountain waves generated by the Appalachian Mountains in the MODIS total column water vapor (CWV) product derived from near-infrared (NIR) (0.94 micrometers) measurements, which indicate perturbations very close to the surface. The CWV waves are usually observed during spring and late fall or some summer days with low to moderate CWV (below is approx. 2 cm). The observed lee waves display wavelengths from3-4 to 15kmwith an amplitude of variation often comparable to is approx. 50-70% of the total CWV. Since the bulk of atmospheric water vapor is confined to the boundary layer, this indicates that the impact of thesewaves extends deep into the boundary layer, and these may be the lowest level signatures of mountain lee waves presently detected by remote sensing over the land.

  12. Forecasting the mortality rates using Lee-Carter model and Heligman-Pollard model

    Science.gov (United States)

    Ibrahim, R. I.; Ngataman, N.; Abrisam, W. N. A. Wan Mohd

    2017-09-01

    Improvement in life expectancies has driven further declines in mortality. The sustained reduction in mortality rates and its systematic underestimation has been attracting the significant interest of researchers in recent years because of its potential impact on population size and structure, social security systems, and (from an actuarial perspective) the life insurance and pensions industry worldwide. Among all forecasting methods, the Lee-Carter model has been widely accepted by the actuarial community and Heligman-Pollard model has been widely used by researchers in modelling and forecasting future mortality. Therefore, this paper only focuses on Lee-Carter model and Heligman-Pollard model. The main objective of this paper is to investigate how accurately these two models will perform using Malaysian data. Since these models involves nonlinear equations that are explicitly difficult to solve, the Matrix Laboratory Version 8.0 (MATLAB 8.0) software will be used to estimate the parameters of the models. Autoregressive Integrated Moving Average (ARIMA) procedure is applied to acquire the forecasted parameters for both models as the forecasted mortality rates are obtained by using all the values of forecasted parameters. To investigate the accuracy of the estimation, the forecasted results will be compared against actual data of mortality rates. The results indicate that both models provide better results for male population. However, for the elderly female population, Heligman-Pollard model seems to underestimate to the mortality rates while Lee-Carter model seems to overestimate to the mortality rates.

  13. Lee Miller à travers la Roumanie, l’appareil photo à la main (1946

    Directory of Open Access Journals (Sweden)

    Adrian-Silvan Ionescu

    2012-01-01

    Full Text Available A former model and fashion photographer turned war photographer, Lee Miller visited Romania twice, in 1938 and 1946 respectively. After her second visit she published her impressions and pictures, under the title of Roumania, in Vogue magazine. Besides the published material there are her manuscripts from The Lee Miller Achives at Farley Farm House, East Sussex, England, on which this paper is based. She crossed the border coming from Hungary in early February 1946. Heading for Sibiu her car, a Chevrolet Sedan, slipping on the ice-covered road, stopped on a snowbank far off in the ditch. While looking for help in the nearby village she and her companions left the car unguarded to discover it plundered of everything, wheels included.On a Sunday afternoon she had the privilege of being received by King Mihai I and Queen Mother Elena with whom she talked exstensively. She also took magnificent pictures with the Royal Family in the imposing Peleş Castle. At Sinaia, „the summer capital of Roumania” she had also the opportunity to portray Dinu Brătianu and Iuliu Maniu, the two elderly statesmen. Maniu was surrounded by friends and party members, among whom was young Corneliu Coposu, his private secretary.Moving to Bucharest, she met old friends such as Harri Brauner and his wife, Lena Constante, with whom she wandered through the country eight years ago. Lena and Elena Pătrășcanu, wife of Lucrețiu Pătrășcanu, Minister of Justice, have started a successful marionette theatre where Lee took nice pictures. Other were taken on the streets, with peasants, street vendors and their customers. Harri took her to a bistro where they met Maria Lătărețu, the celebrating folk singer whom Brauner recorded many times. They enjoyed her songs. Suffering from fibrositis, Lee Miller undertook a peculiar treatment in a gypsy village where the inhabitants were dancing bears trainers. She was massaged by a bear weighing about 300 pounds while Brauner took

  14. Genome-wide methylation analysis in Silver-Russell syndrome patients

    Science.gov (United States)

    Böhm, S; Frost, JM; Puszyk, W; Abu-Amero, S; Stanier, P; Schulz, R; Moore, GE; Oakey, RJ

    2015-01-01

    Silver-Russell Syndrome (SRS) is a clinically heterogeneous disorder characterised by severe in utero growth restriction and poor postnatal growth, body asymmetry, irregular craniofacial features and several additional minor malformations. The aetiology of SRS is complex and current evidence strongly implicates imprinted genes. Approximately half of all patients exhibit DNA hypomethylation at the H19/IGF2 imprinted domain, and around 10% have maternal uniparental disomy of chromosome 7. We measured DNA methylation in 18 SRS patients at >485,000 CpG sites using DNA methylation microarrays. Using a novel bioinformatics methodology specifically designed to identify subsets of patients with a shared epimutation, we analysed methylation changes genome-wide as well as at known imprinted regions to identify SRS-associated epimutations. Our analysis identifies epimutations at the previously characterised domains of H19/IGF2 and at imprinted regions on chromosome 7, providing proof of principle that our methodology can detect DNA methylation changes at imprinted loci. In addition we discovered two novel epimutations associated with SRS and located at imprinted loci previously linked to relevant mouse and human phenotypes. We identify RB1 as an additional imprinted locus associated with SRS, with a region near the RB1 DMR hypermethylated in 13/18 (~70 %) patients. We also report 6/18 (~33 %) patients were hypermethylated at a CpG island near the ANKRD11 gene. We do not observe consistent cooccurrence of epimutations at multiple imprinted loci in single SRS individuals. SRS is clinically heterogeneous and the absence of multiple imprinted loci epimutations reflects the heterogeneity at the molecular level. Further stratification of SRS patients by molecular phenotypes might aid the identification of disease causes. PMID:25563730

  15. A rare case of Silver-Russell syndrome associated with growth hormone deficiency and urogenital abnormalities

    Directory of Open Access Journals (Sweden)

    Namburi Rajendra Prasad

    2012-01-01

    Full Text Available Introduction: Silver-Russell syndrome (SRS is a very rare genetic disorder. This is usually characterized by asymmetry in the size of the two halves or other parts of the body. Background: We are presenting a case of SRS with growth hormone (GH deficiency and urogenital abnormalities. Case Report: A 15-year-old boy a product of non-consanguineous marriage brought with a history of short stature and poor development of secondary sexual characters. There were no adverse perinatal events, but weighed 1500 g (<3 rd centile at birth. He had delayed developmental milestones. He has had a poor appetite and feeding difficulties since childhood. On physical examination, he had a broad forehead, triangular facies, and low-set prominent ears. Asymmetry of the face, upper and lower extremities was noted, with hemihypertrophy on the right side. His height was 119 cm (<3 rd centile and weight was 18 kg which were low (<3 rd centile as per his age. He was biochemically euthyroid and GH stimulation testing with clonidine (0.15 mg/m 2 showed low GH levels at 30×, 60×, and 90× were 1.7, 1.6, and 1.1ng/ml, respectively. On micturatingcystourethrogram, grade V complex was noted on the right side. Dimercaptosuccinic acid (DMSA showed normal functioning kidneys. He was started on recombinant GH with a height velocity of 10 cm/ year. Conclusion : Urogenital abnormalities are rare but well described anomalies associated with SRS, and all cases have to be screened for them. GH deficiency is not uncommon in SRS, and GH treatment proves to be beneficial.

  16. Correction of the axial and appendicular deformities in a patient with Silver-Russel syndrome

    Directory of Open Access Journals (Sweden)

    Ali Al Kaissi

    2015-01-01

    Full Text Available Background: Scoliosis and limb length discrepancy are the major orthopaedic abnormalities in patients with Silver-Russel syndrome (SRS. In this paper, we describe a series of orthopaedic interventions in an attempt to overcome the progressive pathologic mechanism in a 7-year-old girl who manifested the full phenotypic features of SRS. Materials and Methods: Unilateral hip dislocation, progressive scoliosis and limb length discrepancy have been dealt with through Pemberton osteotomy, spinal fusion and Taylor-Spatial-Frame respectively. Results: In order to correct the axial and the appendicular deformities a sum of seven operations were performed (between the age of 7 years and 13 years. Pemberton osteotomy was performed to treat dislocation of her right hip because of developmental dysplasia of the hip. Spinal fusion (spondylodesis of segments Th3-L5 was done to correct her scoliosis. And, to overcome the limb length discrepancy of 15-cm we used Taylor-Spatial-Frame with percutaneous distal corticotomy of the femur, and the proximal tibia, as well as the foot, were performed. We were able to minimize the limb length discrepancy to 5 cm. The girl became able to walk with the aid of a below knee orthosis and through lifting the left limb with 5-cm height shoe. Conclusion: Limb lengthening surgery in patients with multiple malformation complex as in SRS is associated with high recurrence risk because of; muscular hypotonia, overtubulation of the long bones, and the poor bone regenerative quality. Our interventions were principally directed towards improving the cosmetic outlook, functions and the biomechanics.

  17. Regional economic impacts of current and proposed management alternatives for Charles M. Russell National Wildlife Refuge

    Science.gov (United States)

    Koontz, Lynne; Sexton, Natalie; Ishizaki, Asuka; Ritten, John

    2013-01-01

    The National Wildlife Refuge System Improvement Act of 1997 requires all units of the National Wildlife Refuge System to be managed under a Comprehensive Conservation Plan (CCP). The CCP must describe the desired future conditions of a refuge and provide long-range guidance and management direction to achieve refuge purposes. Charles M. Russell (CMR) National Wildlife Refuge, located in north-central Montana, is in the process of developing a range of management goals, objectives, and strategies for the CCP. The CCP for the Refuge must contain an analysis of expected effects associated with current and proposed refuge-management strategies. For refuge CCP planning, an economic analysis provides a means of estimating how current management (No Action Alternative) and proposed management activities (Alternatives) affect the local economy. This type of analysis provides two critical pieces of information: (1) it illustrates a refuge’s contribution to the local community; and (2) it can help in determining whether economic effects are or are not a real concern in choosing among management alternatives. It is important to note that the economic value of a refuge encompasses more than just the impacts on the regional economy. Refuges also provide substantial nonmarket values (values for items not exchanged in established markets) such as maintaining endangered species, preserving wetlands, educating future generations, and adding stability to the ecosystem (Carver and Caudill, 2007). However, quantifying these types of nonmarket values is beyond the scope of this study. This report first presents a description of the local community and economy near the Refuge. Next, the methods used to conduct a regional economic impact analysis are described. An analysis of the final CCP management strategies that could affect stakeholders and residents and the local economy is then presented. The refuge management activities of economic concern in this analysis are:

  18. Limb lengthening in children with Russell-Silver syndrome: a comparison to other etiologies.

    Science.gov (United States)

    Goldman, V; McCoy, T H; Harbison, M D; Fragomen, A T; Rozbruch, S R

    2013-03-01

    Russell-Silver syndrome (RSS) is the combination of intrauterine growth retardation, difficulty feeding, and postnatal growth retardation. Leg length discrepancy (LLD) is one of four major diagnostic criteria of RSS and is present in most cases. We aimed to ascertain whether pediatric RSS patients will adequately consolidate bony regenerate following leg lengthening. We retrospectively reviewed pediatric RSS patients who underwent limb lengthening and compared them to a similar group of patients with LLD resulting from tumor, trauma, or congenital etiology. The primary outcome measurement was the bone healing index (BHI). The RSS group included seven lengthened segments in five patients; the comparison group included 21 segments in 19 patients. The groups had similar lengthening amounts (3.3 vs. 3.9 cm, p = 0.507). The RSS group healed significantly faster (lower BHI) than the control group (BHI 29 vs. 43 days/cm, p = 0.028). Secondary analysis showed no difference between RSS and trauma patients in terms of the BHI (29 vs. 31); however, the BHI of the RSS group was significantly lower than both of the other congenital etiologies (29 vs. 41, p = 0.032) and tumor patients (29 vs. 66, p = 0.019). The RSS patients had fewer and less significant complications than the controls. The limb lengthening regenerate healing of RSS patients is faster than the healing of patients with other congenital etiologies and tumor patients, and is as fast as the regenerate healing of patients with posttraumatic LLD. Although all RSS patients were treated with human growth hormone (hGH), we are unable to isolate the hGH contribution to the regenerate bone healing. We conclude that RSS patients can have safe limb lengthening.

  19. 78 FR 77508 - Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined...

    Science.gov (United States)

    2013-12-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined Licenses Application Review AGENCY: Nuclear Regulatory Commission. ACTION: Final environmental impact...

  20. H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Jonathan A Levine

    Full Text Available Enteropathogenic E. coli (EPEC and enterohemorrhagic E. coli are important causes of morbidity and mortality worldwide. These enteric pathogens contain a type III secretion system (T3SS responsible for the attaching and effacing (A/E lesion phenotype. The T3SS is encoded by the locus of enterocyte effacement (LEE pathogenicity island. The H-NS-mediated repression of LEE expression is counteracted by Ler, the major activator of virulence gene expression in A/E pathogens. A regulator present in EPEC, H-NST, positively affects expression of H-NS regulon members in E. coli K-12, although the effect of H-NST on LEE expression and virulence of A/E pathogens has yet-to-be determined.We examine the effect of H-NST on LEE expression and A/E lesion formation on intestinal epithelial cells. We find that H-NST positively affects the levels of LEE-encoded proteins independently of ler and induces A/E lesion formation. We demonstrate H-NST binding to regulatory regions of LEE1 and LEE3, the first report of DNA-binding by H-NST. We characterize H-NST mutants substituted at conserved residues including Ala16 and residues Arg60 and Arg63, which are part of a potential DNA-binding domain. The single mutants A16V, A16L, R60Q and the double mutant R60Q/R63Q exhibit a decreased effect on LEE expression and A/E lesion formation. DNA mobility shift assays reveal that these residues are important for H-NST to bind regulatory LEE DNA targets. H-NST positively affects Ler binding to LEE DNA in the presence of H-NS, and thereby potentially helps Ler displace H-NS bound to DNA.H-NST induces LEE expression and A/E lesion formation likely by counteracting H-NS-mediated repression. We demonstrate that H-NST binds to DNA and identify arginine residues that are functionally important for DNA-binding. Our study suggests that H-NST provides an additional means for A/E pathogens to alleviate repression of virulence gene expression by H-NS to promote virulence capabilities.

  1. H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.

    Science.gov (United States)

    Levine, Jonathan A; Hansen, Anne-Marie; Michalski, Jane M; Hazen, Tracy H; Rasko, David A; Kaper, James B

    2014-01-01

    Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of morbidity and mortality worldwide. These enteric pathogens contain a type III secretion system (T3SS) responsible for the attaching and effacing (A/E) lesion phenotype. The T3SS is encoded by the locus of enterocyte effacement (LEE) pathogenicity island. The H-NS-mediated repression of LEE expression is counteracted by Ler, the major activator of virulence gene expression in A/E pathogens. A regulator present in EPEC, H-NST, positively affects expression of H-NS regulon members in E. coli K-12, although the effect of H-NST on LEE expression and virulence of A/E pathogens has yet-to-be determined. We examine the effect of H-NST on LEE expression and A/E lesion formation on intestinal epithelial cells. We find that H-NST positively affects the levels of LEE-encoded proteins independently of ler and induces A/E lesion formation. We demonstrate H-NST binding to regulatory regions of LEE1 and LEE3, the first report of DNA-binding by H-NST. We characterize H-NST mutants substituted at conserved residues including Ala16 and residues Arg60 and Arg63, which are part of a potential DNA-binding domain. The single mutants A16V, A16L, R60Q and the double mutant R60Q/R63Q exhibit a decreased effect on LEE expression and A/E lesion formation. DNA mobility shift assays reveal that these residues are important for H-NST to bind regulatory LEE DNA targets. H-NST positively affects Ler binding to LEE DNA in the presence of H-NS, and thereby potentially helps Ler displace H-NS bound to DNA. H-NST induces LEE expression and A/E lesion formation likely by counteracting H-NS-mediated repression. We demonstrate that H-NST binds to DNA and identify arginine residues that are functionally important for DNA-binding. Our study suggests that H-NST provides an additional means for A/E pathogens to alleviate repression of virulence gene expression by H-NS to promote virulence capabilities.

  2. 'Items for criticism (not in sequence)': Joseph DeLee, Pare Lorentz and The Fight for Life (1940).

    Science.gov (United States)

    Gainty, Caitjan

    2017-09-01

    In the late 1920s, the American obstetrician Joseph DeLee brought the motion-picture camera into the birth room. Following that era's trend of adapting industrial efficiency practices for medical environments, DeLee's films give spectacular and unexpected expression to the engineering concept of 'streamlining'. Accomplishing what more tangible obstetric streamlining practices had failed to, DeLee's cameras, and his post-production manipulation, shifted birth from messy and dangerous to rationalized, efficient, death-defying. This was film as an active and effective medical tool. Years later, the documentarian Pare Lorentz produced and wrote his own birth film, The Fight for Life (1940). The documentary subject of the film was DeLee himself, and the film was set in his hospitals, on the same maternity 'sets' that had once showcased film's remarkable streamlining capacity to give and keep life. Yet relatively little of DeLee was retained in the film's content, resulting in a showdown that, by way of contrast, further articulated DeLee's understanding of film's medical powers and, in so doing, hinted at a more dynamic moment in the history of medicine while speaking also to the process by which that understanding ceased to be historically legible.

  3. Potential of lees from wine, beer and cider manufacturing as a source of economic nutrients: An overview.

    Science.gov (United States)

    Pérez-Bibbins, B; Torrado-Agrasar, A; Salgado, J M; Oliveira, R Pinheiro de Souza; Domínguez, J M

    2015-06-01

    Lees are the wastes generated during the fermentation and aging processes of different industrial activities concerning alcoholic drinks such as wine, cider and beer. They must be conveniently treated to avoid uncontrolled dumping which causes environmental problems due to their high content of phenols, pesticides, heavy metals, and considerable concentrations of nitrogen, phosphate and potassium as well as high organic content. The companies involved must seek alternative environmental and economic physicochemical and biological treatments for their revalorization consisting in the recovery or transformation of the components of the lees into high value-added compounds. After describing the composition of lees and market of wine, beer and cider industries in Spain, this work aims to review the recent applications of wine, beer and cider lees reported in literature, with special attention to the use of lees as an endless sustainable source of nutrients and the production of yeast extract by autolysis or cell disruption. Lees and/or yeast extract can be used as nutritional supplements with potential exploitation in the biotechnological industry for the production of natural compounds such as xylitol, organic acids, and biosurfactants, among others. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Learning the ropes at Richard B. Russell Dam: Net systems for medium head hydropower pumpback and generation fish sampling

    Energy Technology Data Exchange (ETDEWEB)

    Schilt, C.R. [AscI Corporation, Inc., Calhoun Falls, SC (United States)]|[Univ. of Georgia, Athens, GA (United States); Vu, P.D. [Nylon Net Co., Memphis, TN (United States); Nestler, J.M. [USAE Waterways Experiment Station, Vicksburg, MS (United States)

    1995-12-31

    At Richard B. Russell Dam on the Savannah River we have been monitoring the magnitude (numbers and masses) and species compositions as well as possible survival of fish entrained in operation of four 85 MW Francis pump turbines. In this paper we review our progress in net design for hydropower application. We also discuss basic net handling and introduce a method for net management in a very turbulent tailrace. This report is meant to share what we have learned at Russell Dam in hopes that it will facilitate similar efforts elsewhere. The commercial fishing industry has evolved methods of net construction and handling that may be applied, with appropriate modification, at dams. The nets we use are most appropriately called trawls in that they have the form of a long sock placed over the penstock or draft tube. These nets are superficially similar to those used in commercial trawling for fish. Important differences are that: (1) the net remains relatively stationary while the water moves through it, not vice versa; (2) water velocities and turbulence are much greater at dams than in commercial fishing operations and (3) mesh sizes are much smaller for environmental sampling than for commercial trawling. And while a fouled trawl may stop the boat that pulls it, the water passed in generation or pumpback (about 140 ft. head at Russell) is for all practical purposes unstoppable. Our nets fish in a very turbulent discharge at 7,000 cu. ft./sec/turbine. Their strength and their ability to pass water effectively under all possible operating conditions are primary concerns. Trawl length, mesh sizes, and hanging ratios are important factors. Although we have had setbacks (usually in the form of torn nets) as this study has developed, we have incrementally improved our net design and handling. We review our net failures and the solutions we have found thus far in both construction and handling.

  5. Structural and sequence variants in patients with Silver-Russell syndrome or similar features-Curation of a disease database

    DEFF Research Database (Denmark)

    Tümer, Zeynep; López-Hernández, Julia Angélica; Netchine, Irène

    2018-01-01

    Silver-Russell syndrome (SRS) is a clinically and molecularly heterogeneous disorder involving prenatal and postnatal growth retardation, and the term SRS-like is broadly used to describe individuals with clinical features resembling SRS. The main molecular subgroups are loss of methylation...... data of these patients. The clinical features are scored according to the Netchine-Harbison clinical scoring system (NH-CSS), which has recently been accepted as standard by consensus. The structural and sequence variations are reviewed and where necessary redescribed according to recent...

  6. Generation of hyperchaos from the Chen-Lee system via sinusoidal perturbation

    Energy Technology Data Exchange (ETDEWEB)

    Tam, L.M. [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Thomas Pereira S.J., Taipa, Macau (China)], E-mail: fstlmt@umac.mo; Chen, J.H. [Department of Mechanical Engineering, Chung Hua University, Hsinchu, Taiwan (China); Chen, H.K. [Department of Mechanical Engineering, Hsiuping Institute of Technology, Taichung, Taiwan (China); Wai Meng Si Tou [Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Av. Padre Thomas Pereira S.J., Taipa, Macau (China)

    2008-11-15

    A system with more than one positive Lyapunov exponent can be classified as a hyperchaotic system. In this study, a sinusoidal perturbation was designed for generating hyperchaos from the Chen-Lee chaotic system. The hyperchaos was identified by the existence of two positive Lyapunov exponents and bifurcation diagrams. The system is hyperchaotic in several different regions of the parameters c, {epsilon}, and {omega}. It was found that this method not only can enhance or suppress chaotic behavior, but also induces chaos in non-chaotic parameter ranges. In addition, two interesting dynamical behaviors, Hopf bifurcation and intermittency, were also found in this study.

  7. Adaptation of Sing Lee's model to the Filippov type plasma focus geometry

    International Nuclear Information System (INIS)

    Siahpoush, V; Tafreshi, M A; Sobhanian, S; Khorram, S

    2005-01-01

    A new model for plasma behaviour in Filippov type plasma focus (PF) systems has been described and used. This model is based on the so-called slug model and Sing Lee's model for Mather type PF devices. Using the model, the discharge current and its derivative as a function of time, and the pinch time and the maximum discharge current as a function of pressure, have been predicted. At the end, the predicted data are compared with the experimental data obtained through a Filippov type PF facility with a nominal maximum energy of 90 kJ

  8. Heritability and complex segregation analysis of deafness in Jack Russell Terriers

    Directory of Open Access Journals (Sweden)

    Strain George M

    2007-11-01

    Full Text Available Abstract Background The association between patterns of pigmentation and deafness in the dog has a long-documented history, with reports dating back over one hundred years. Long suspected of having a genetic basis, the search for loci with a pronounced influence in the expression of hearing loss in the dog has yet to be successful. No studies in the dog to date have found a possible influence of a specific colour locus associated with deafness. The present study is intended to evaluate the heritability of deafness in the Jack Russell Terrier (JRT, characterize the mode of inheritance, and evaluate the existence of a sex, coat colour, or coat texture influence on the expression of sensorineural deafness. Results The estimation of heritability of deafness in the JRT was 0.22 when deafness was considered a binary (normal/deaf trait and 0.31 when deafness was considered a three-category (normal/unilateral/bilateral deafness. The influence of coat colour in the incidence of JRT deafness was statistically significant, indicating that dogs with more white are more likely to be deaf. The influence of sex or coat texture was not statistically significant in the incidence of JRT deafness. Complex segregation analysis revealed a model of a single locus with a large effect on the binary measure of hearing loss is not supported. Conclusion This is the first attempt, to our knowledge, to characterize a genetic component responsible for deafness in the JRT. The heritability of deafness in the JRT was found to be 0.22 and 0.31 considering deafness to be a two-category or three-category trait, respectively. There appears to be an influence of coat colour on the expression of deafness. In an attempt to characterize the mode of inheritance of deafness in the JRT, a model of a single locus with a large effect on hearing loss is not supported with this data. Further study is needed to determine if a single locus may be influencing deafness in the JRT. While the

  9. Carpal tunnel syndrome, syndrome of partial thenar atrophy, and W. Russell Brain: a historical perspective.

    Science.gov (United States)

    Boskovski, Marko T; Thomson, J Grant

    2014-09-01

    This article presents the history of the discovery of compression of the median nerve in the carpal tunnel without an identifiable cause as a distinct clinical entity. By analyzing primary sources, we show that, at the beginning of the twentieth century, physicians described patients with paresthesias and numbness in the hands, most prominent at night, accompanied by bilateral symmetrical atrophy along the radial side of thenar eminence. At the time, the 2 most influential hypotheses regarding etiology were, first, compression of the lower trunk of the brachial plexus by a cervical or first rib, and second, compression of the thenar branch of the median nerve as it passes beneath the anterior annular ligament of the wrist. The condition was named syndrome of partial thenar atrophy and was considered a distinct clinical entity. In 1946, after extensive analysis, neurologist Walter Russell Brain concluded that both sensory and motor symptoms of the syndrome were caused by "compression neuritis" of the median nerve in the carpal tunnel. At his suggestion, surgeon Arthur Dickson Wright performed decompression of the nerve by "an incision of the carpal ligament," with excellent results. Brain presented this work at the Royal Society of Medicine in London in 1946 and published his landmark paper in Lancet the following year. In so doing, he established the basis for the disease we know today as idiopathic carpal tunnel syndrome. Unfortunately, in 1947, Brain did not realize that another "condition" with the same clinical picture but without atrophy of the thenar muscles, known as acroparesthesia at the time, was actually the same disease as syndrome of partial thenar atrophy, but of lesser severity. As a result of Brain's influence, 7 other papers were published by 1950. Between 1946 and 1950, there were at least 10 papers that presented, in total, 31 patients (26 women) who exhibited symptoms of compression of the median nerve without an identifiable cause and underwent

  10. Detection of venom after antivenom is not associated with persistent coagulopathy in a prospective cohort of Russell's viper (Daboia russelii envenomings.

    Directory of Open Access Journals (Sweden)

    Kalana Maduwage

    2014-12-01

    Full Text Available Venom recurrence or persistence in the circulation after antivenom treatment has been documented many times in viper envenoming. However, it has not been associated with clinical recurrence for many snakes, including Russell's viper (Daboia spp.. We compare the recovery of coagulopathy to the recurrence or persistence of venom in patients with Russell's viper envenoming.The study included patients with Russell's viper (D. russelii envenoming presenting over a 30 month period who had Russell's viper venom detected by enzyme immunoassay. Demographics, information on the snake bite, and clinical effects were collected for all patients. All patients had serum collected for venom specific enzyme immunoassay and citrate plasma to measure fibrinogen levels and prothrombin time (international normalised ratio; INR. Patients with venom recurrence/persistence were compared to those with no detectable recurrence of venom. There were 55 patients with confirmed Russell's viper envenoming and coagulopathy with low fibrinogen concentrations: 31 with venom recurrence/persistence, and 24 with no venom detected post-antivenom. Fibrinogen concentrations increased and INR decreased after antivenom in both the recurrence and non-recurrence patients. Clinical features, laboratory parameters, antivenom dose and length of hospital were similar for both groups. Pre-antivenom venom concentrations were higher in patients with venom recurrence/persistence with a median venom concentration of 385 ng/mL (16-1521 ng/mL compared to 128 ng/mL (14-1492 ng/mL; p = 0.008.Recurrence of Russell's viper venom was not associated with a recurrence of coagulopathy and length of hospital stay. Further work is required to determine if the detection of venom recurrence is due to the venom specific enzyme immunoassay detecting both venom-antivenom complexes as well as free venom.

  11. Visioni vittoriane: il paesaggio fiorentino nelle opere di Janet Ross e Vernon Lee

    Directory of Open Access Journals (Sweden)

    Gabriele Corsani

    2015-11-01

    Full Text Available Fra l’ultimo scorcio dell’Ottocento e i primi decenni del Novecento Firenze e i suoi dintorni sono il soggetto privilegiato di una grande quantità di descrizioni, note di diario, racconti, opera di scrittori stranieri, in particolare inglesi, che si radicano nell’approdo elettivo di quei luoghi. Il testo presenta la traccia letteraria del paesaggio fiorentino nelle opere di Vernon Lee e Janet Ross, due tipiche rappresentanti di questa tendenza che hanno vissuto, attraverso vicende biografiche in qualche modo parallele, un’esperienza di intensa identificazione con il paesaggio fiorentino. Di Janet Ross, viene commentato Old Florence and Modern Tuscany, volume che raccoglie una serie di articoli pubblicati su alcune riviste inglesi e fornisce una efficace panoramica sull’interesse molto concreto di Janet Ross per il mondo rurale che la vede addirittura impegnata nella gestione della fattoria di Castagnolo, a Lastra a Signa. Più sfaccettato è il commento alle opere di Vernon Lee, di cui sono commentati passi da Vanitas. Polite Stories, Genius Loci, Hortus Vitae and Limbo, in virtù della maggiore ampiezza e complessità del suo mondo culturale. Ne sono cifra distintiva la associazione fra storia e realtà attraverso la dimensione del mistero, che risulta una delle chiavi di acccesso alla bellezza e alla vitalità del paesagggio e la capacità di cogliere il ritmo proprio dei luoghi e di entrare in reale sintonia con essi. 

  12. Electricity generation using white and red wine lees in air cathode microbial fuel cells

    Science.gov (United States)

    Pepe Sciarria, Tommy; Merlino, Giuseppe; Scaglia, Barbara; D'Epifanio, Alessandra; Mecheri, Barbara; Borin, Sara; Licoccia, Silvia; Adani, Fabrizio

    2015-01-01

    Microbial fuel cell (MFC) is a useful biotechnology to produce electrical energy from different organic substrates. This work reports for the first time results of the application of single chamber MFCs to generate electrical energy from diluted white wine (WWL) and red wine (RWL) lees. Power obtained was of 8.2 W m-3 (262 mW m-2; 500 Ω) and of 3.1 W m-3 (111 mW m-2; 500Ω) using white and red wine lees, respectively. Biological processes lead to a reduction of chemical oxygen (TCOD) and biological oxygen demand (BOD5) of 27% and 83% for RWL and of 90% and 95% for WWL, respectively. These results depended on the degradability of organic compounds contained, as suggest by BOD5/TCOD of WWL (0.93) vs BOD5/TCOD of RWL (0.33), and to the high presence of polyphenols in RWL that inhibited the process. Coulombic efficiency (CE) of 15 ± 0%, for WWL, was in line with those reported in the literature for other substrates, i.e. CE of 14.9 ± 11.3%. Different substrates led to different microbial consortia, particularly at the anode. Bacterial species responsible for the generation of electricity, were physically connected to the electrode, where the direct electron transfer took place.

  13. Grape marc, wine lees and deposit of the must: How to manage oenological by-products?

    Directory of Open Access Journals (Sweden)

    Lempereur Valérie

    2014-01-01

    Full Text Available Winemaking produces solid (grape marc and liquid (wine lees and deposit of the must wastes named “oenological by-products”, which, according to European regulations, must be eliminated following the environmental regulatory requirement [1]. In France, these European regulations forced wine growers, until the 2013/2014 campaign, to deliver all by-products to wine distilleries. This French obligation is known as the “prestation vinique” [2, 3]. Following the Common Market Organisation wine reform, a consultation was initiated by FranceAgriMer on the potential value of oenological by-products. The French Institute of Vine and Wine (IFV coordinated a national experimentation from 2010 to 2013 about recovery of by-products, with the support of members of the Technical Group: Association des Viticulteurs d'Alsace (AVA, Comité Interprofessionnel du Vin de Champagne (CIVC, Institut Technique des Corps Gras (ITERG, et Union Nationale des Groupements de Distillateurs d'Alcool (UNGDA. Distillation of grape marc and wine lees spreading and composting, and anaerobic digestion of grape marc were studied in order to answer the following questions: What technical feasibility? What environmental impact? What cost for winegrowers? What conformity with the regulations, including environmental regulatory obligations? [4].

  14. South Korean Government under the former CEO, President Lee Myung-bak

    Directory of Open Access Journals (Sweden)

    Eunsook Yang

    2008-10-01

    Full Text Available Tras un prometedor inicio gracias a su arrolladora victoria en diciembre del 2007 y portando un mandato para llevar a cabo profundas reformas económicas, el presidente Lee Myung-bak se ha visto obligado a recuperar la confianza de su ciudadanía tras las duras críticas a numerosos aspectos de su política: la importación de carne vacuna bajo el Tratado de Libre Comercio EEUU-Corea del Sur pendiente de aprobación, sus ambiciosos proyectos de construcción, su agenda de privatizaciones y su estilo algo autoritario. Las características de su política exterior resultan interesantes por los contrastes con su predecesor: refuerzo de la alianza con los EEUU, mejora de las relaciones con Japón, mayor dinamismo en su diplomacia energética hacia Rusia, mayor envergadura a su relación con China y una postura más firme hacia Corea del Norte. Sin embargo Lee Myung-bak ha de superar el desafío que la crisis económica mundial le presenta y así poder restaurar la situación económica de su país.

  15. Vitis vinifera L. cv Pinot noir pomace and lees as potential sources of bioactive compounds.

    Science.gov (United States)

    Reis, Gabriel M; Faccin, Henrique; Viana, Carine; Rosa, Marcelo Barcellos da; de Carvalho, Leandro M

    2016-11-01

    Food and agricultural industries generate substantial quantities of phenolic-rich by-products that could be valuable natural sources of antioxidants. The aim of this study was to identify and quantify the phenolic compounds and radical scavenging activities of two by-products (pomace and lees) from Vitis vinifera L. cv Pinot noir. We found a different distribution of phenolic classes (flavanols, flavonols, phenolic acids and stilbenes) and singular scavenging activity against free radicals (hydroxyl, superoxide and peroxyl radicals). The major class of phenolics in pomace was flavanols and in lees was flavonols, with catechin (117.9 ± 2.5 μg g(-1)) and quercetin (42.4 ± 1.2 μg g(-1)) being the most abundant individual compounds. We also found high potential on scavenging activity against superoxide radicals in pomace (80% of scavenging activity) and radical peroxyl (67% scavenging activity). These results show the possibility of using Pinot noir by-products as promising additives or as a source for the development of new products in different segments of the food and cosmetic industries.

  16. Nonsingular cosmology with a scale-invariant spectrum of cosmological perturbations from Lee-Wick theory

    International Nuclear Information System (INIS)

    Cai Yifu; Qiu Taotao; Brandenberger, Robert; Zhang Xinmin

    2009-01-01

    We study the cosmology of a Lee-Wick type scalar field theory. First, we consider homogeneous and isotropic background solutions and find that they are nonsingular, leading to cosmological bounces. Next, we analyze the spectrum of cosmological perturbations which result from this model. Unless either the potential of the Lee-Wick theory or the initial conditions are finely tuned, it is impossible to obtain background solutions which have a sufficiently long period of inflation after the bounce. More interestingly, however, we find that in the generic noninflationary bouncing cosmology, perturbations created from quantum vacuum fluctuations in the contracting phase have the correct form to lead to a scale-invariant spectrum of metric inhomogeneities in the expanding phase. Since the background is nonsingular, the evolution of the fluctuations is defined unambiguously through the bounce. We also analyze the evolution of fluctuations which emerge from thermal initial conditions in the contracting phase. The spectrum of gravitational waves stemming from quantum vacuum fluctuations in the contracting phase is also scale-invariant, and the tensor to scalar ratio is not suppressed.

  17. Polyphenols from Wine Lees as a Novel Functional Bioactive Compound in the Protection Against Oxidative Stress and Hyperlipidaemia

    Directory of Open Access Journals (Sweden)

    Irena Landeka Jurčević

    2017-01-01

    Full Text Available The study examines the potential of wine industry by-product, the lees, as a rich mixture of natural polyphenols, and its physiological potential to reduce postprandial metabolic and oxidative stress caused by a cholesterol-rich diet in in vivo model. Chemical analysis of wine lees showed that their total solid content was 94.2 %. Wine lees contained total phenols, total nonflavonoids and total flavonoids expressed in mg of gallic acid equivalents per 100 g of dry mass: 2316.6±37.9, 1332.5±51.1 and 984.1±28.2, respectively. The content of total anthocyanins expressed in mg of cyanidin-3-glucoside equivalents per 100 g of dry mass was 383.1±21.6. Antioxidant capacity of wine lees determined by the DPPH and FRAP methods and expressed in mM of Trolox equivalents per 100 g was 259.8±1.8 and 45.7±1.05, respectively. The experiment lasted 60 days using C57BL/6 mice divided in four groups: group 1 was fed normal diet and used as control, group 2 was fed normal diet with added wine lees, group 3 was fed high-cholesterol diet (HCD, i.e. normal diet with the addition of sunflower oil, and group 4 was fed HCD with wine lees. HCD increased serum total cholesterol (TC by 2.3-fold, triacylglycerol (TAG by 1.5-fold, low-density lipoprotein (LDL by 3.5-fold and liver malondialdehyde (MDA by 50 %, and reduced liver superoxide dismutase (SOD by 50 %, catalase (CAT by 30 % and glutathione (GSH by 17.5 % compared to control. Conversely, treatment with HCD and wine lees reduced TC and LDL up to 1.4 times more than with HCD only, with depletion of lipid peroxidation (MDA and restoration of SOD and CAT activities in liver, approximating values of the control. HDL levels were unaffected in any group. Serum transaminase activity showed no hepatotoxic properties in the treatment with lees alone. In the proposed model, wine lees as a rich polyphenol source could be a basis for functional food products without alcohol.

  18. « Russell Banks goes Creole » : A Talk with the Author of The Book of Jamaica and Continental Drift

    OpenAIRE

    Cooreman, Kathleen Gyssels et Gaëlle

    2008-01-01

    Cette interview avec Russell Banks, auteur consacré de notamment The Book of Jamaica (1980) et Continental Drift (1985), tous deux traduits en français chez Actes Sud, a été menée le 27 mai 2007 par Kathleen Gyssels et Gaëlle Cooreman (Université d’Anvers). Elles interrogent Banks sur son idée du Great American Novel, son engagement vis-à-vis de la diaspora africaine et ses romans « caribéens », The Book of Jamaica et Continental Drift.This interview with Russell Banks, acknowledged author of...

  19. Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE) Pathogenicity Island in EnteropathogenicEscherichia coli.

    Science.gov (United States)

    Leh, Hervé; Khodr, Ahmad; Bouger, Marie-Christine; Sclavi, Bianca; Rimsky, Sylvie; Bury-Moné, Stéphanie

    2017-08-08

    In enteropathogenic Escherichia coli (EPEC), the locus of enterocyte effacement (LEE) encodes a type 3 secretion system (T3SS) essential for pathogenesis. This pathogenicity island comprises five major operons ( LEE1 to LEE5 ), with the LEE5 operon encoding T3SS effectors involved in the intimate adherence of bacteria to enterocytes. The first operon, LEE1 , encodes Ler (LEE-encoded regulator), an H-NS (nucleoid structuring protein) paralog that alleviates the LEE H-NS silencing. We observed that the LEE5 and LEE1 promoters present a bimodal expression pattern, depending on environmental stimuli. One key regulator of bimodal LEE1 and LEE5 expression is ler expression, which fluctuates in response to different growth conditions. Under conditions in vitro considered to be equivalent to nonoptimal conditions for virulence, the opposing regulatory effects of H-NS and Ler can lead to the emergence of two bacterial subpopulations. H-NS and Ler share nucleation binding sites in the LEE5 promoter region, but H-NS binding results in local DNA structural modifications distinct from those generated through Ler binding, at least in vitro Thus, we show how two nucleoid-binding proteins can contribute to the epigenetic regulation of bacterial virulence and lead to opposing bacterial fates. This finding implicates for the first time bacterial-chromatin structural proteins in the bimodal regulation of gene expression. IMPORTANCE Gene expression stochasticity is an emerging phenomenon in microbiology. In certain contexts, gene expression stochasticity can shape bacterial epigenetic regulation. In enteropathogenic Escherichia coli (EPEC), the interplay between H-NS (a nucleoid structuring protein) and Ler (an H-NS paralog) is required for bimodal LEE5 and LEE1 expression, leading to the emergence of two bacterial subpopulations (with low and high states of expression). The two proteins share mutual nucleation binding sites in the LEE5 promoter region. In vitro , the binding of H

  20. RcsB determines the locus of enterocyte effacement (LEE) expression and adherence phenotype of Escherichia coli O157 : H7 spinach outbreak strain TW14359 and coordinates bicarbonate-dependent LEE activation with repression of motility.

    Science.gov (United States)

    Morgan, Jason K; Vendura, Khoury W; Stevens, Stanley M; Riordan, James T

    2013-11-01

    The 2006 US spinach outbreak of Escherichia coli O157 : H7, characterized by unusually severe disease, has been attributed to a strain (TW14359) with enhanced pathogenic potential, including elevated virulence gene expression, robust adherence and the presence of novel virulence factors. This study proposes a mechanism for the unique virulence expression and adherence phenotype of this strain, and further expands the role for regulator RcsB in control of the E. coli locus of enterocyte effacement (LEE) pathogenicity island. Proteomic analysis of TW14359 revealed a virulence proteome consistent with previous transcriptome studies that included elevated levels of the LEE regulatory protein Ler and type III secretion system (T3SS) proteins, secreted T3SS effectors and Shiga toxin 2. Basal levels of the LEE activator and Rcs phosphorelay response regulator, RcsB, were increased in strain TW14359 relative to O157 : H7 strain Sakai. Deletion of rcsB eliminated inherent differences between these strains in ler expression, and in T3SS-dependent adherence. A reciprocating regulatory pathway involving RcsB and LEE-encoded activator GrlA was identified and predicted to co-ordinate LEE activation with repression of the flhDC flagellar regulator and motility. Overexpression of grlA was shown to increase RcsB levels, but did not alter expression from promoters driving rcsB transcription. Expression of rcsDB and RcsB was determined to increase in response to physiological levels of bicarbonate, and bicarbonate-dependent stimulation of the LEE was shown to be dependent on an intact Rcs system and ler activator grvA. The results of this study significantly broaden the role for RcsB in enterohaemorrhagic E. coli virulence regulation.

  1. Interpretation for ''high''-Tc of the totally interconnected solution of the Ma and Lee model

    International Nuclear Information System (INIS)

    Wiecko, C.

    1988-09-01

    The already presented totally interconnected (mean-field) approximation of the Ma and Lee model, pictures very well many ingredients of the present status of comprehension of high-T c superconductors. The picture is that of a disordered grain with variable number of particles available for an attractive on-site pairing interaction, embedded in a reservoir of normal particles which fix the chemical potential. Interesting effect of absence of T c and then a sharp increase and slow decay of T c with disorder appears for weak coupling pairing as compared with the hopping probability for single particles. Interpretation is given in terms of one-particle Anderson localization theory and standard mechanisms. (author). 13 refs, 4 figs

  2. Lee-Yang-inspired functional with a density-dependent neutron-neutron scattering length

    Science.gov (United States)

    Grasso, M.; Lacroix, D.; Yang, C. J.

    2017-05-01

    Inspired by the low-density Lee-Yang expansion for the energy of a dilute Fermi gas of density ρ and momentum kF, we introduce here a Skyrme-type functional that contains only s -wave terms and provides, at the mean-field level, (i) a satisfactory equation of state for neutron matter from extremely low densities up to densities close to the equilibrium point, and (ii) a good-quality equation of state for symmetric matter at density scales around the saturation point. This is achieved by using a density-dependent neutron-neutron scattering length a (ρ ) which satisfies the low-density limit (for Fermi momenta going to zero) and has a density dependence tuned in such a way that the low-density constraint |a (ρ ) kF|≤1 is satisfied at all density scales.

  3. Vernon Lee in the Vatican: the uneasy alliance of aestheticism and archaeology.

    Science.gov (United States)

    Evangelista, Stefano

    2009-01-01

    From the 1800s onward, aesthetic critics attempted to free the study of ancient Greek art from the frameworks of institutional education and professionalized criticism. In this process, aestheticism entered an uneasy alliance with archaeology, a discipline that was likewise challenging traditional modes of classical learning practiced in public schools and the old universities. In "The Child in the Vatican" (1881), Vernon Lee -- writing under the influence of Pater and from a position of cosmopolitan female amateurism -- examines the uses of archaeological science in the study of classical art. Her analysis of the sculptures of the Niobe Group at once relies on the archaeological method and asks readers to doubt scientific approaches to art that dim the sublime power of the art object.

  4. Enigmatic eight-meter trace fossils in the Lower Pennsylvanian Lee sandstone, central Appalachian basin, Tennessee

    Science.gov (United States)

    Wnuk, C.; Maberry, J.O.

    1990-01-01

    Enigmatic tubular trace fossils up to eight meters long occur in the Lower Pennsylvanian Middlesboro Member of the Lee Formation. Two morphotypes occur: type 1 trace fossils are plain, smooth, vertical, nonbranching, parallel-walled, tubular structures, type 2 trace fossils branch, have walls with faint vertical striations, regularly or irregularly spaced nodes, and funnel-shaped terminations. Sandstone casts filling type 2 structures have helical spiral morphology, and, in rare individuals, faint meniscate fills have been observed. Both trace-fossil morphotypes have poorly cemented wall linings containing framboidal pyrite, amorphous carbon, quartz sand, and poorly preserved fecal material. The trace fossils occur in a massive, structureless, channel-form sandstone, originating at the contact between a channel lag and the overlying massive fill representing a barrier island transgressing an estuarine facies. Origin of these structures is uncertain. -from Authors

  5. The Yang-Lee edge singularity for the Ising model on two Sierpinski fractal lattices

    Energy Technology Data Exchange (ETDEWEB)

    Knezevic, Milan [Faculty of Physics, University of Belgrade, PO Box 368, 11000 Belgrade (Serbia); Knezevic, Dragica, E-mail: knez@ff.bg.ac.r, E-mail: dknezevic@kg.ac.r [Faculty of Natural Sciences and Mathematics, University of Kragujevac, PO Box 60, 34000 Kragujevac (Serbia)

    2010-10-15

    We study the distribution of zeros of the partition function of the ferromagnetic Ising model near the Yang-Lee edge on two Sierpiski-type lattices. We have shown that relevant correlation length displays a logarithmic divergence near the edge, {xi}{sub YL{approx}}|ln({partial_derivative}h)|{sup {Phi}} where {Phi} is a constant and {delta}h distance from the edge, in the case of a modified Sierpinski gasket with a nonuniform coordination number. It is demonstrated that this critical behavior can be related to the critical behavior of a simple zero-field Gaussian model of the same structure. We have shown that there is no such connection between these two models on a second lattice that has a uniform coordination number. These findings suggest that fluctuations of the lattice coordination number of a nonhomogeneous self-similar structure exert the crucial influence on the critical behavior of both models.

  6. Deletions and rearrangements of the H19/IGF2 enhancer region in patients with Silver-Russell syndrome and growth retardation

    DEFF Research Database (Denmark)

    Grønskov, Karen; Poole, Rebecca L; Hahnemann, Johanne M D

    2011-01-01

    Silver-Russell syndrome (SRS) is characterised by prenatal and postnatal growth retardation, dysmorphic facial features, and body asymmetry. In 35-60% of SRS cases the paternally methylated imprinting control region (ICR) upstream of the H19 gene (H19-ICR) is hypomethylated, leading to downregula...

  7. The Colour Treatment: A Convergence of Art and Medicine at the Red Cross Russell Lea Nerve Home.

    Science.gov (United States)

    Berryman, Jim

    2016-01-01

    When the Red Cross opened its new convalescent home at Russell Lea in Sydney in 1919, it contained a coloured room designed for treating ‘nerve cases’. This room was painted by Roy de Maistre, a young artist, and was modelled on the Kemp Prossor colour scheme trialled at the McCaul Convalescent Hospital in London for the treatment of shell shock. Dubbed the ‘colour cure’ by the popular press, this unconventional treatment was ignored by the Australian medical profession. The story of de Maistre's colour experiment is not widely known outside the specialist field of Australian art history. Focusing on the colour room as a point of convergence between art and medicine in the context of the First World War, this article investigates Red Cross activities and the care of soldiers suffering from nervous conditions.

  8. Helicobacter pylori-negative Russell body gastritis: does the diagnosis call for screening for plasmacytic malignancies, especially multiple myeloma?

    Science.gov (United States)

    Klair, Jagpal Singh; Girotra, Mohit; Kaur, Aneet; Aduli, Farshad

    2014-01-01

    Russell body gastritis (RBG) is a rare entity with unestablished pathophysiology, endoscopic findings, clinical manifestations and treatments. Literature is scarce on this clinical entity with unclear clinical significance. Of 18 cases reported, 12 tested (+) for Helicobacter pylori and improved with treatment, but it remains unclear whether this link is coincidental or bears some clinical significance. We describe a case of elderly woman who had a follow-up oesophagogastroduodenoscopy for chronic peptic ulcers, and biopsy showed positive immunohistochemical stains for κ and λ, indicating a polytypic population of plasma cells. Immunostaining for H pylori was negative. Biopsies were also (−) for gastric carcinoma, lymphoma and plasmacytoma. Considering her RGB-suggestive histology and her symptoms of bone pains and anaemia, multiple myeloma screening was considered clinically relevant. The purpose of this review was to educate clinicians and gastroenterologists about this unique entity and explore its association with multiple myeloma or other plamacytic malignancies. PMID:24671320

  9. Differences in dental and bone maturation in regions with or without hemihypertrophy in two patients with Russell-Silver syndrome.

    Science.gov (United States)

    Orbak, Zerrin; Orbak, Recep; Kara, Cankat; Kavrut, Fahri

    2005-07-01

    Hemihypertrophy (hemihyperplasia) is defined as asymmetric body overgrowth of one or more body parts. Hemihypertrophy can be isolated or be part of well-defined syndromes, such as Russell-Silver syndrome (RSS). RSS is characterized by severe intrauterine growth retardation, postnatal short stature, asymmetry of the face, body, and limbs, short and incurved fifth fingers, broad forehead, pointed small triangular shaped face, girdle nose, normal psychomotor development, variations in the pattern of sexual development, and dental and oral abnormalities. The aim of this study was to determine whether or not there was any difference in the maturity of bone in left and right hand-wrist radiographs and dental development in the right and left jaws of two patients with RSS. In addition, the clinical features of the syndrome are discussed.

  10. The Importance of Collaboration in Advancing Understanding of Rare Disorders: US/EU Joint Initiative on Silver-Russell Syndrome.

    Science.gov (United States)

    Salem, Jennifer B; Netchine, Irène; Harbison, Madeleine D

    2017-11-01

    Patient-support organizations can facilitate a significant change in the way rare disorders are approached. Besides connecting families with each other and directing patients to experienced medical specialists, these groups, by collaborating with government initiatives like COST, can effect the direction and funding of rare disease research. By concentrating the rare disease patient population and funneling them to specific centers of excellence, these organizations help build specialists' experience and their study populations. It requires a basic spirit of collaboration, driven parent leaders, a well-organized support platform, sources of funding, supportive clinical and research professionals and finally an effective method of collecting and disseminating information. Silver-Russell Syndrome is an excellent example of a rare disorder that has become better recognized, understood and treated because patient-support organizations, using the internet as a critical tool, have worked together with clinical care/research specialists and public funding agencies to build collaboration. Copyright© of YS Medical Media ltd.

  11. Population Pharmacokinetics of an Indian F(ab'2 Snake Antivenom in Patients with Russell's Viper (Daboia russelii Bites.

    Directory of Open Access Journals (Sweden)

    Geoffrey K Isbister

    Full Text Available There is limited information on antivenom pharmacokinetics. This study aimed to investigate the pharmacokinetics of an Indian snake antivenom in humans with Russell's viper bites.Patient data and serial blood samples were collected from patients with Russell's viper (Daboia russelii envenoming in Sri Lanka. All patients received Indian F(ab'2 snake antivenom manufactured by VINS Bioproducts Ltd. Antivenom concentrations were measured with sandwich enzyme immunoassays. Timed antivenom concentrations were analysed using MONOLIXvs4.2. One, two and three compartment models with zero order input and first order elimination kinetics were assessed. Models were parameterized with clearance (CL, intercompartmental clearance (Q, central compartment volume (V and peripheral compartment volume (VP. Between-subject-variability (BSV on relative bioavailability (F was included to account for dose variations. Covariates effects (age, sex, weight, antivenom batch, pre-antivenom concentrations were explored by visual inspection and in model building. There were 75 patients, median age 57 years (40-70 y and 64 (85% were male. 411 antivenom concentration data points were analysed. A two compartment model with zero order input, linear elimination kinetics and a combined error model best described the data. Inclusion of BSV on F and weight as a covariate on V improved the model. Inclusion of pre-antivenom concentrations or different batches on BSV of F did not. Final model parameter estimates were CL,0.078 L h(-1, V,2.2L, Q,0.178 L h(-1 and VP,8.33L. The median half-life of distribution was 4.6 h (10-90%iles:2.6-7.1 h and half-life of elimination, 140 h (10th-90th percentilesx:95-223h.Indian F(ab'2 snake antivenom displayed biexponential disposition pharmacokinetics, with a rapid distribution half-life and more prolonged elimination half-life.

  12. Neurotoxicity in Sri Lankan Russell's Viper (Daboia russelii) Envenoming is Primarily due to U1-viperitoxin-Dr1a, a Pre-Synaptic Neurotoxin.

    Science.gov (United States)

    Silva, Anjana; Kuruppu, Sanjaya; Othman, Iekhsan; Goode, Robert J A; Hodgson, Wayne C; Isbister, Geoffrey K

    2017-01-01

    Russell's vipers are snakes of major medical importance in Asia. Russell's viper (Daboia russelii) envenoming in Sri Lanka and South India leads to a unique, mild neuromuscular paralysis, not seen in other parts of the world where the snake is found. This study aimed to identify and pharmacologically characterise the major neurotoxic components of Sri Lankan Russell's viper venom. Venom was fractionated using size exclusion chromatography and reverse-phase high-performance liquid chromatography (RP-HPLC). In vitro neurotoxicities of the venoms, fractions and isolated toxins were measured using chick biventer and rat hemidiaphragm preparations. A phospholipase A 2 (PLA 2 ) toxin, U1-viperitoxin-Dr1a (13.6 kDa), which constitutes 19.2 % of the crude venom, was isolated and purified using HPLC. U1-viperitoxin-Dr1a produced concentration-dependent in vitro neurotoxicity abolishing indirect twitches in the chick biventer nerve-muscle preparation, with a t 90 of 55 ± 7 min only at 1 μM. The toxin did not abolish responses to acetylcholine and carbachol indicating pre-synaptic neurotoxicity. Venom, in the absence of U1-viperitoxin-Dr1a, did not induce in vitro neurotoxicity. Indian polyvalent antivenom, at the recommended concentration, only partially prevented the neurotoxic effects of U1-viperitoxin-Dr1a. Liquid chromatography mass spectrometry analysis confirmed that U1-viperitoxin-Dr1a was the basic S-type PLA 2 toxin previously identified from this venom (NCBI-GI: 298351762; SwissProt: P86368). The present study demonstrates that neurotoxicity following Sri Lankan Russell's viper envenoming is primarily due to the pre-synaptic neurotoxin U1-viperitoxin-Dr1a. Mild neurotoxicity observed in severely envenomed Sri Lankan Russell's viper bites is most likely due to the low potency of U1-viperitoxin-Dr1a, despite its high relative abundance in the venom.

  13. A Conversation with Lee Shulman--Signature Pedagogies for Teacher Education: Defining Our Practices and Rethinking Our Preparation

    Science.gov (United States)

    Falk, Beverly

    2006-01-01

    Lee S. Shulman is the President of The Carnegie Foundation for the Advancement of Teaching, a foundation whose mission is "to do and perform all things necessary to encourage, uphold and dignify the profession of teaching." Prior to assuming his role at Carnegie, Shulman was the Charles E. Ducommun Professor of Education at Stanford…

  14. 76 FR 79228 - Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy...

    Science.gov (United States)

    2011-12-21

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy Carolinas, LLC AGENCY: Nuclear Regulatory Commission. ACTION: Draft environmental impact statement; public...

  15. Q & A with Ed Tech Leaders: Interview with Curtis J. Bonk, Mimi Miyoung Lee, Thomas C. Reeves, & Thomas H. Reynolds

    Science.gov (United States)

    Viner, Mark; Gardner, Ellen; Shaughnessy, Michael F.

    2016-01-01

    Curtis J. Bonk, is Professor of Instructional Systems Technology at Indiana University and President of CourseShare. Mimi Miyoung Lee is Associate Professor in the Department of Curriculum and instruction at the University of Houston. Thomas C. Reeves is Professor Emeritus of Learning, Design, and Technology at the University of Georgia. Thomas H.…

  16. General Robert E. Lee (1807-70) and Philanthropist George Peabody (1795-1869) at White Sulphur Springs, West Virginia, July 23-Aug. 30, 1869.

    Science.gov (United States)

    Parker, Franklin; Parker, Betty J.

    This paper discusses the chance meeting at White Sulphur Springs (West Virginia) of two important public figures, Robert E. Lee and George Peabody, whose rare encounter marked a symbolic turn from Civil War bitterness toward reconciliation and the lifting power of education. The paper presents an overview of Lee's life and professional and…

  17. Effect of Saccharomyces strains on the quality of red wines aged on lees.

    Science.gov (United States)

    Loira, I; Vejarano, R; Morata, A; Ricardo-da-Silva, J M; Laureano, O; González, M C; Suárez-Lepe, J A

    2013-08-15

    Ageing on lees involves ageing the wine in contact with yeast cells after fermentation. If combined with the addition of oak chips, it can soften the wood flavour and increase the aromatic complexity of wine. The aim of the present work is to optimise both ageing techniques through selection of an adequate Saccharomyces cerevisiae strain. The study lasted 6 months and content of polysaccharides, anthocyanins, proanthocyanidins, volatile compounds, colour parameters and sensory analysis, were periodically evaluated. Among the strains tested, G37 showed the highest release of polysaccharides (24.4±5.5 mg l(-1)). Vanillin, syringaldehyde and furfuryl alcohol increased with ageing time in 7VA2 treatment. The wine aged with CTPL14 strain presented fewer monomeric and oligomeric proanthocyanidins (12.4±0.6 and 83.4±8.3 mg l(-1), respectively), and showed the lowest astringency and bitterness sensations. Results show an improvement in the sensory profile of the red wine aged with a combination of these two techniques. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Lee-Carter state space modeling: Application to the Malaysia mortality data

    Science.gov (United States)

    Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

    2014-06-01

    This article presents an approach that formalizes the Lee-Carter (LC) model as a state space model. Maximum likelihood through Expectation-Maximum (EM) algorithm was used to estimate the model. The methodology is applied to Malaysia's total population mortality data. Malaysia's mortality data was modeled based on age specific death rates (ASDR) data from 1971-2009. The fitted ASDR are compared to the actual observed values. However, results from the comparison of the fitted and actual values between LC-SS model and the original LC model shows that the fitted values from the LC-SS model and original LC model are quite close. In addition, there is not much difference between the value of root mean squared error (RMSE) and Akaike information criteria (AIC) from both models. The LC-SS model estimated for this study can be extended for forecasting ASDR in Malaysia. Then, accuracy of the LC-SS compared to the original LC can be further examined by verifying the forecasting power using out-of-sample comparison.

  19. Structural modeling of age specific fertility curves in Peninsular Malaysia: An approach of Lee Carter method

    Science.gov (United States)

    Hanafiah, Hazlenah; Jemain, Abdul Aziz

    2013-11-01

    In recent years, the study of fertility has been getting a lot of attention among research abroad following fear of deterioration of fertility led by the rapid economy development. Hence, this study examines the feasibility of developing fertility forecasts based on age structure. Lee Carter model (1992) is applied in this study as it is an established and widely used model in analysing demographic aspects. A singular value decomposition approach is incorporated with an ARIMA model to estimate age specific fertility rates in Peninsular Malaysia over the period 1958-2007. Residual plots is used to measure the goodness of fit of the model. Fertility index forecast using random walk drift is then utilised to predict the future age specific fertility. Results indicate that the proposed model provides a relatively good and reasonable data fitting. In addition, there is an apparent and continuous decline in age specific fertility curves in the next 10 years, particularly among mothers' in their early 20's and 40's. The study on the fertility is vital in order to maintain a balance between the population growth and the provision of facilities related resources.

  20. Hartree-Fock treatment of Fermi polarons using the Lee-Low-Pine transformation

    Science.gov (United States)

    Kain, Ben; Ling, Hong Y.

    2017-09-01

    We consider the Fermi polaron problem at zero temperature, where a single impurity interacts with noninteracting host fermions. We approach the problem starting with a Fröhlich-like Hamiltonian where the impurity is described with canonical position and momentum operators. We apply the Lee-Low-Pine (LLP) transformation to change the fermionic Fröhlich Hamiltonian into the fermionic LLP Hamiltonian, which describes a many-body system containing host fermions only. We adapt the self-consistent Hartree-Fock (HF) approach, first proposed by Edwards, to the fermionic LLP Hamiltonian in which a pair of host fermions with momenta k and k' interact with a potential proportional to k .k' . We apply the HF theory, which has the advantage of not restricting the number of particle-hole pairs, to repulsive Fermi polarons in one dimension. When the impurity and host fermion masses are equal our variational ansatz, where HF orbitals are expanded in terms of free-particle states, produces results in excellent agreement with McGuire's exact analytical results based on the Bethe ansatz. This work raises the prospect of using the HF ansatz and its time-dependent generalization as building blocks for developing all-coupling theories for both equilibrium and nonequilibrium Fermi polarons in higher dimensions.

  1. Nobelist TD LEE Scientist Cooperation Network and Scientist Innovation Ability Model

    Directory of Open Access Journals (Sweden)

    Jin-Qing Fang

    2013-01-01

    Full Text Available Nobelist TD Lee scientist cooperation network (TDLSCN and their innovation ability are studied. It is found that the TDLSCN not only has the common topological properties both of scale-free and small-world for a general scientist cooperation networks, but also appears the creation multiple-peak phenomenon for number of published paper with year evolution, which become Nobelist TD Lee’s significant mark distinguished from other scientists. This new phenomenon has not been revealed in the scientist cooperation networks before. To demonstrate and explain this new finding, we propose a theoretical model for a nature scientist and his/her team innovation ability. The theoretical results are consistent with the empirical studies very well. This research demonstrates that the model has a certain universality and can be extended to estimate innovation ability for any nature scientist and his/her team. It is a better method for evaluating scientist innovation ability and his/her team for the academic profession and is of application potential.

  2. The spirit of St Louis: the contributions of Lee N. Robins to North American psychiatric epidemiology.

    Science.gov (United States)

    Campbell, Nancy D

    2014-08-01

    This article takes up the history of North American psychiatric epidemiology with reference to production of knowledge concerning sociopathic or antisocial personality disorder and drug dependence, abuse, and/or addiction. These overlapping arenas provide a microcosm within which to explore the larger shift of postwar psychiatric epidemiology from community studies based on psychological scales to studies based on specific diagnostic criteria. This paper places the figure of sociologist Lee Nelken Robins within the context of the Department of Psychiatry in the School of Medicine at Washington University in St Louis, Missouri. The St Louis research group--to which Robins was both marginal and central--developed the basis for specific diagnostic criteria and was joined by Robert Spitzer, Jean Endicott and other architects of DSM-III in reorienting American psychiatry towards medical, biological and epidemiological models. Robins was a key linchpin working at the nexus of the psychiatric epidemiological and sociological drug addiction research networks. This article situates her work within the broader set of societal and governmental transformations leading to the technologically sophisticated turn in American psychiatric epidemiology and research on the aetiology of drug abuse and mental health and illness. Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2013; all rights reserved.

  3. The other Higgses, at resonance, in the Lee-Wick extension of the Standard Model

    CERN Document Server

    Figy, Terrance

    2011-01-01

    Within the framework of the Lee Wick Standard Model (LWSM) we investigate Higgs pair production $gg \\to h_0 h_0$, $gg \\to h_0 \\tilde p_0$ and top pair production $gg \\to \\bar tt$ at the Large Hadron Collider (LHC), where the neutral particles from the Higgs sector ($h_0$, $\\tilde h_0$ and $\\tilde p_0$) appear as possible resonant intermediate states. We investigate the signal $gg \\to h_0 h_0 \\to \\bar b b \\gamma \\gamma$ and we find that the LW Higgs, depending on its mass-range, can be seen not long after the LHC upgrade in 2012. More precisely this happens when the new LW Higgs states are below the top pair threshold. In $gg \\to \\bar tt$ the LW states, due to the wrong-sign propagator and negative width, lead to a dip-peak structure instead of the usual peak-dip structure which gives a characteristic signal especially for low-lying LW Higgs states. We comment on the LWSM and the forward-backward asymmetry in view of the measurement at the TeVatron. Furthermore, we present a technique which reduces the hyperbo...

  4. Damming of Russell Fiord by Tidewater Hubbard Glacier, Alaska: Role of Subglacial Meltwater in Preventing Closure in 2010

    Science.gov (United States)

    Lawson, D. E.; Hamilton, G. S.; Finnegan, D. C.; Stearns, L. A.; Willems, B. A.; O'Neel, S.; Goff, J. A.; Gulick, S. P.; Davis, M. B.

    2010-12-01

    The Hubbard Glacier is advancing into tidewater at a net annual average rate of ~32 m/yr resulting from a seasonal cycle of advance and retreat ranging from less than 100 meters to over 600 meters per year. The eastern margin of the glacier fronts on Gilbert Point where a tidal channel connecting Disenchantment Bay and Russell Fiord could be dammed by ice with continuing advance; after filling to ~43m elevation, lake waters would drain into an abandoned channel of the Situk River and cross the coastal plain near the Town of Yakutat. Ice dams formed in 1986 and 2002 but both dams failed within six months; the Hubbard Glacier came within 60 meters of closing the channel in 2009, but failed to achieve closure before the seasonal retreat phase began in mid-summer. On going field investigations of ice flow and ice face motion and the ice marginal environment provide a means to evaluate the processes and parameters that may limit closure rates and thus the ability of the glacier to dam the connecting channel. The seasonal cycle commonly limits first closure by ice to the period of time before slowing and retreat begins, typically late June to mid-July. Seasonally increasing ice flow rate, rising air temperature and net solar flux, cool sea water temperature, high tidal range, fast currents between Russell Fiord and Disenchantment Bay, and meltwater influx and submarine discharge all appear important to determining the closure rate in and adjacent to the channel at Gilbert Point. In 2010, the primary control on ice marginal advance appears to be subglacial meltwater discharging as distinct jets from subglacial conduits and as expansive sheet flows from thin films on the bed of the glacier. Climatic data and local observations of snowfall suggest that warm winter temperatures and a large snow fall provided meltwater in large volume to the glacier bed earlier than previous years of record (limited), and that discharge locations migrated laterally, affecting a wider area

  5. ANÁLISIS DEL PROBLEMA MENTE-CEREBRO DESDE LA TEORÍA DEL DOBLE ASPECTO O MONISMO NEUTRAL PROPUESTA POR BERTRAND RUSSELL

    OpenAIRE

    Ana Cecilia Vallejo Clavijo

    2007-01-01

    El presente trabajo investigativo plantea un análisis sobre el problema mente- cerebro desde la Teoría del doble aspecto, o más exactamente, desde la Teoría del monismo neutral planteada por Bertrand Russell. Este análisis presenta la armonización de dos tendencias que pueden parecer aparentemente contradictorias; una en el campo de la psicología, y la otra, en el de la física. Para Russell el tema de la relación de la materia con lo que existe, y en general, la interpretación en términos de ...

  6. Details of the general numerical solutions of the Friedberg-Lee soliton model for ground and exited states

    International Nuclear Information System (INIS)

    Koeppel, T.; Harvey, M.

    1984-06-01

    A new numerical method is applied to solving the equations of motion of the Friedberg-Lee Soliton model for both ground and spherically symmetric excited states. General results have been obtained over a wide range of parameters. Critical coupling constants and critical particle numbers have been determined below which soliton solutions cease to exist. The static properties of the proton are considered to show that as presently formulated the model fails to fit all experimental data for any set of parameters

  7. Extraordinary Claims Require Extraordinary Evidence: C. H. Payne, H. N. Russell and Standards of Evidence in Early Quantitative Stellar Spectroscopy

    Science.gov (United States)

    DeVorkin, David H.

    2010-01-01

    The ionization equilibrium theory of Meghnad Saha was hardly four years old, and still far from general acceptance, when a graduate student at Harvard, Cecilia H. Payne, applied it to calibrate the Harvard spectral sequence as a temperature sequence. Payne indeed utilized Saha's relation not in its original form, but in its more acceptable rederived form based upon a statistical mechanical rederivation by Milne and Fowler. Her temperature calibration was, therefore, not at issue for her mentors at Harvard, such as Harlow Shapley, and her external reviewer for her PhD, the influential Princeton astronomer Henry Norris Russell. Other conclusions she drew from her analysis, moreover, went beyond the evidence, they felt, and so she had to moderate her most provocative finding: that hydrogen dominated the atmospheres of the stars. She did so, however, in a manner that was designed to record for posterity that she was the first to make this observation, right or wrong. In so doing, Payne can be credited with profound political acumen, a quality that deserves more attention in the history of 20th century astronomy.

  8. Alfred Russel Wallace (1823-1913): the forgotten co-founder of the Neo-Darwinian theory of biological evolution.

    Science.gov (United States)

    Kutschera, Ulrich; Hossfeld, Uwe

    2013-12-01

    The British naturalist Alfred Russel Wallace (1823-1913), who had to leave school aged 14 and never attended university, did extensive fieldwork, first in the Amazon River basin (1848-1852) and then in Southeast Asia (1854-1862). Based on this experience, and after reading the corresponding scientific literature, Wallace postulated that species were not created, but are modified descendants of pre-existing varieties (Sarawak Law paper, 1855). Evolution is brought about by a struggle for existence via natural selection, which results in the adaptation of those individuals in variable populations who survive and reproduce (Ternate essay, 1858). In his monograph Darwinism (1889), and in subsequent publications, Wallace extended the contents of Darwin's Origin of Species (1859) into the Neo-Darwinian theory of biological evolution, with reference to the work of August Weismann (1834-1914). Wallace also became the (co)-founder of biogeography, biodiversity research, astrobiology and evolutionary anthropology. Moreover, he envisioned what was later called the anthropocene (i.e., the age of human environmental destructiveness). However, since Wallace believed in atheistic spiritualism and mixed up scientific facts and supernatural speculations in some of his writings, he remains a controversial figure in the history of biology.

  9. Engaging with Lyell: Alfred Russel Wallace's Sarawak Law and Ternate papers as reactions to Charles Lyell's Principles of Geology.

    Science.gov (United States)

    Costa, J T

    2013-12-01

    Alfred Russel Wallace (1823-1913) and Charles Darwin (1809-1882) are honored as the founders of modern evolutionary biology. Accordingly, much attention has focused on their relationship, from their independent development of the principle of natural selection to the receipt by Darwin of Wallace's essay from Ternate in the spring of 1858, and the subsequent reading of the Wallace and Darwin papers at the Linnean Society on 1 July 1858. In the events of 1858 Wallace and Darwin are typically seen as central players, with Darwin's friends Charles Lyell (1797-1875) and Joseph Dalton Hooker (1817-1911) playing supporting roles. This narrative has resulted in an under-appreciation of a more central role for Charles Lyell as both Wallace's inspiration and foil. The extensive anti-transmutation arguments in Lyell's landmark Principles of Geology were taken as the definitive statement on the subject. Wallace, in his quest to solve the mystery of species origins, engaged with Lyell's arguments in his private field notebooks in a way that is concordant with his engagement with Lyell in the 1855 and 1858 papers. I show that Lyell was the object of Wallace's Sarawak Law and Ternate papers through a consideration of the circumstances that led Wallace to send his Ternate paper to Darwin, together with an analysis of the material that Wallace drew upon from the Principles. In this view Darwin was, ironically, intended for a supporting role in mediating Wallace's attempted dialog with Lyell.

  10. Pathogenicity, Ovicidal Action, and Median Lethal Concentrations (LC 50 ) of Entomopathogenic Fungi against Exotic Spiralling Whitefly, Aleurodicus dispersus Russell.

    Science.gov (United States)

    Thangavel, Boopathi; Palaniappan, Karuppuchamy; Manickavasagam Pillai, Kalyanasundaram; Subbarayalu, Mohankumar; Madhaiyan, Ravi

    2013-01-01

    Biological control using entomopathogenic fungi could be a promising alternative to chemical control. Entomopathogenic fungi, Beauveria bassiana (Balsamo) Vuillemin, Metarhizium anisopliae (Metschnikoff) Sorokin, Lecanicillium lecanii (Zimmerm.) Zare and Gams, and Paecilomyces fumosoroseus (Wize) Brown and Smith, were tested for their pathogenicity, ovicidal effect, and median lethal concentrations (LC50) against exotic spiralling whitefly, Aleurodicus dispersus Russell. The applications were made at the rate of 2 × 10(9) conidia mL(-1) for evaluating the pathogenicity and ovicidal effect of entomopathogenic fungi against A. dispersus. The results of pathogenicity test showed that P. fumosoroseus (P1 strain) was highly pathogenic to A. dispersus recording 100% mortality at 15 days after treatment (DAT). M. anisopliae (M2 strain) had more ovicidal effect causing 37.3% egg mortality at 8 DAT. However, L. lecanii (L1 strain) caused minimum egg hatchability (23.2%) at 10 DAT as compared to control (92.6%). The lowest LC50 produced by P. fumosoroseus (P1 strain) as 8.189 × 10(7) conidia mL(-1) indicated higher virulence against A. dispersus. Hence, there is potential for use of entomopathogenic fungi in the field conditions as an alternate control method in combating the insect pests and other arthropod pests since they are considered natural mortality agents and are environmentally safe.

  11. Diurnal variability of inner-shelf circulation in the lee of a cape under upwelling conditions

    Science.gov (United States)

    Lamas, L.; Peliz, A.; Dias, J.; Oliveira, P. B.; Angélico, M. M.; Castro, J. J.; Fernandes, J. N.; Trindade, A.; Cruz, T.

    2017-07-01

    The nearshore circulation in the lee of a cape under upwelling conditions was studied using in-situ data from 3 consecutive summers (2006-2008). Focus was given to a period between 20 July and 04 August 2006 to study the diurnal variability of the cross-shelf circulation. This period was chosen because it had a steady upwelling-favourable wind condition modulated by a diurnal cycle much similar to sea breeze. The daily variability of the observed cross-shelf circulation consisted of three distinct periods: a morning period with a 3-layer vertical structure with onshore velocities at mid-depth, a mid-day period where the flow is reversed and has a 2-layer structure with onshore velocities at the surface and offshore flow below, and, lastly, in the evening, a 2-layer period with intensified offshore velocities at the surface and onshore flow at the bottom. The observed cross-shelf circulation showed a peculiar vertical shape and diurnal variability different from several other systems described in literature. We hypothesize that the flow reversal of the cross-shelf circulation results as a response to the rapid change of the wind magnitude and direction at mid-day with the presence of the cape north of the mooring site influencing this response. A numerical modelling experiment exclusively forced by winds simulated successfully most of the circulation at the ADCP site, especially the mid-day reversal and the evening's upwelling-type structure. This supports the hypothesis that the cross-shelf circulation at diurnal timescales is mostly wind-driven. By analysing the 3D circulation in the vicinity of Cape Sines we came to the conclusion that the diurnal variability of the wind and the flow interaction with topography are responsible for the circulation variability at the ADCP site, though only a small region in the south of the cape showed a similar diurnal variability. The fact that the wind diurnally undergoes relaxation and intensification strongly affects the

  12. "Embodiment as procedures: Physical cleansing changes goal priming effects": Correction to Dong and Lee (2017).

    Science.gov (United States)

    2017-06-01

    Reports an error in "Embodiment as procedures: Physical cleansing changes goal priming effects" by Ping Dong and Spike W. S. Lee ( Journal of Experimental Psychology: General , 2017[Apr], Vol 146[4], 592-605). In the article, the following F-value and p-values in the Results section of Experiment 3 were set incorrectly: The p -value p =.925 should be p =.922. The F - and p -values F (1, 201)=.011, p =.916 should be F (1, 201) .014, p = .906. (The following abstract of the original article appeared in record 2017-14922-010.) Physical cleansing reduces the influence of numerous psychological experiences, such as guilt from immoral behavior, dissonance from free choice, and good/bad luck from winning/losing. How do these domain-general effects occur? We propose an integrative account of cleansing as an embodied procedure of psychological separation. By separating physical traces from a physical target object (e.g., detaching dirt from hands), cleansing serves as the embodied grounding for the separation of psychological traces from a psychological target object (e.g., dissociating prior experience from the present self). This account predicts that cleansing reduces the accessibility of psychological traces and their consequences for judgments and behaviors. Testing these in the context of goal priming, we find that wiping one's hands (vs. not) decreases the mental accessibility (Experiment 1), behavioral expression (Experiment 2), and judged importance (Experiments 3-4) of previously primed goals (e.g., achievement, saving, fitness). But if a goal is primed after cleansing, its importance gets amplified instead (Experiment 3). Based on the logic of moderation-of-process, an alternative manipulation that psychologically separates a primed goal from the present self produces the same effects, but critically, the effects vanish once people wipe their hands clean (Experiment 4), consistent with the notion that cleansing functions as an embodied procedure of psychological

  13. A ten-year observation of somatic development of a first group of Polish children with Silver-Russell syndrome.

    Science.gov (United States)

    Sienko, Magdalena; Petriczko, Elżbieta; Zajaczek, Stanislaw; Zygmunt-Gorska, Agata; Starzyk, Jerzy; Korpysz, Alicja; Petriczko, Jan; Walczak, Alicja; Walczak, Mieczyslaw

    2014-01-01

    Silver-Russell syndrome is heterogeneous both clinically and genetically. The best known genetic aberrations existing in this syndrome are an 11p15 epimutation, present in 20-60% patients, and a maternal uniparental chromosome 7 disomy (7-15%) (upd(7)mat). Children with SRS suffer from physical growth impairments - intrauterine and after birth. The study group consisted of 38 children aged 2 to 17 (x=8.9 ± 4.0 years). These children had undergone a genetic analysis in search for the 11p15 epimutation and the upd(7)mat. Somatic growth was also analysed in terms of birth parameters and postnatal BMI, weight and height. The aforementioned parameters were compared in a subgroup of children with the genetic aberrations and with a control group of children born with IUGR. In the study group a mean weight SD on birth was -3.41 ± 1.22, the birth height was -1.25 ± 2.08 SD and a head circumference of -3.56 ± 1.93 SD. No significant differences were noted between the SRS study group and the control group in reference to weight and head circumference (p>0.05). Such difference was, however, seen in birth height. Children with 11p15 epimutation had significantly lower weight and height at birth, but a significantly larger head circumference than children without this genetic aberration. When analysing further development of children with SRS, a significantly smaller height SD, body mass and BMI was observed, compared with children from the control group. Children with SRS present impaired somatic development compared to children with IUGR, and these with a genetic aberration develop worse.

  14. Amino acid residues in the Ler protein critical for derepression of the LEE5 promoter in enteropathogenic E. coli.

    Science.gov (United States)

    Choi, Su-Mi; Jeong, Jae-Ho; Choy, Hyon E; Shin, Minsang

    2016-08-01

    Enteropathogenic E. coli causes attaching and effacing (A/E) intestinal lesions. The genes involved in the formation of A/E lesions are encoded within a chromosomal island comprising of five major operons, LEE1-5. The global regulator H-NS represses the expression of these operons. Ler, a H-NS homologue, counteracts the H-NS-mediated repression. Using a novel genetic approach, we identified the amino acid residues in Ler that are involved in the interaction with H-NS: I20 and L23 in the C-terminal portion of α-helix 3, and I42 in the following unstructured linker region.

  15. A linear model for rotors produced by trapped lee waves with a simple representation of boundary layer friction

    Science.gov (United States)

    Teixeira, Miguel A. C.

    2017-04-01

    A linear model is used to diagnose the onset of rotors in flow over 2D ridges, for atmospheres that are neutrally stratified near the surface and stably stratified aloft, with a sharp temperature inversion in between, where trapped lee waves may propagate. This is achieved by coupling an inviscid two-layer mountain-wave model with a bulk boundary-layer model. The full model shows some ability to detect flow stagnation as a function of key input parameters, such as the Froude number and the height of the inversion, by comparison with results from numerical simulations and laboratory experiments carried out by previous authors. The effect of a boundary layer is essential to correctly predict flow stagnation, as the inviscid version of the model severely overestimates the dimensionless critical mountain height necessary for stagnation to occur. An improved model that includes only the effects of mean flow deceleration and amplification of the velocity perturbation within the boundary layer predicts flow stagnation much better in the most non-hydrostatic cases treated here, where waves appear to be directly forced by the orography. However, in the most hydrostatic case, only the full model, taking into account the feedback of the boundary layer on the inviscid flow, satisfactorily predicts flow stagnation, although the corresponding stagnation condition is unable to discriminate between rotors and hydraulic jumps. This is due to the fact that the trapped lee waves associated with the rotors are not forced directly by the orography in this case, but rather seem to be generated indirectly by nonlinear processes. This mechanism is, to a certain extent, mimicked by the modified surface boundary condition adopted in the full model, where an "effective orography" that differs from the real one forces the trapped lee waves. Versions of the model not including this feedback severely underestimate the amplitude of the trapped lee waves in the most hydrostatic case, partly

  16. Okhee Lee, Cory A. Buxton, James A. Banks (ed.), Diversity and equity in science education: research, policy, and practice

    Science.gov (United States)

    Bannier, Betsy J.

    2015-06-01

    Highly relevant for academic study among K-12 educators and the higher education faculty who train pre-service teachers, Diversity and equity in science education highlights three interrelated issues impacting science education in the United States. First, complicated dynamics related to the large and increasing population of English language learning (ELL) students are discussed. Second, the realities of standardized test scores are comparatively explored, both within and beyond the United States. Third, the politics of accountability in education are vigorously discussed. Okhee Lee and Cory A. Buxton weave through the contexts of politics, education, science, and culture to expand existing discourse about how to best educate our nation's children.

  17. Esse tal de Roque Enrow! : a trajetória de Rita Lee de outsider ao mainstream (1967-1985)

    OpenAIRE

    Gohl, Jeffferson William

    2014-01-01

    O presente trabalho acompanhou parte da trajetória da artista Rita Lee Jones no período entre 1967 até 1985. Valendo-se de fontes, discográficas, documentos audiovisuais, documentos de arquivo e discursos produzidos pela imprensa, procurou documentar desde o momento contracultural em que ela participou do grupo Os Mutantes junto aos movimentos da Tropicália, até seu momento de reconhecimento de maturidade artística que ocorre concomitante ao término do Regime Militar autoritário no Brasil. ...

  18. Mente y Materia. Una exposición crítica de la filosofía de Bertrand Russell

    OpenAIRE

    Pérez Jara, Javier

    2012-01-01

    A lo largo de las páginas que componen el trabajo que el lector tiene en sus manos, trataré de analizar de un modo cr ... D. G. Brown, el autor de un interesante estudio doctoral titulado Bertrand Russell's earlier views on the nature of mind and matter 1911-1919, exponía esto así: La elección de examinar un periodo restringido tiene tanto ventajas como desventajas. Mientras que por una parte disfrutaremos del beneficio de ser capaces de explorar con más profundidad un área limitada, por otra...

  19. The reliability of age measurements for Young Stellar Objects from Hertzsprung-Russell or color-magnitude diagrams

    International Nuclear Information System (INIS)

    Preibisch, Thomas

    2012-01-01

    The possibility to estimate ages and masses of Young Stellar Objects (YSOs) from their location in the Hertzsprung-Russell diagram (HRD) or a color-magnitude diagram provides a very important tool for the investigation of fundamental questions related to the processes of star formation and early stellar evolution. Age estimates are essential for studies of the temporal evolution of circumstellar material around YSOs and the conditions for planet formation. The characterization of the age distribution of the YSOs in a star forming region allows researchers to reconstruct the star formation history and provides important information on the fundamental question of whether star formation is a slow or a fast process. However, the reliability of these age measurements and the ability to detect possible age spreads in the stellar population of star forming regions are fundamentally limited by several factors. The variability of YSOs, unresolved binary components, and uncertainties in the calibrations of the stellar parameters cause uncertainties in the derived luminosities that are usually much larger than the typical photometry errors. Furthermore, the pre-main sequence evolution track of a YSO depends to some degree on the initial conditions and the details of its individual accretion history. I discuss how these observational and model uncertainties affect the derived isochronal ages, and demonstrate how neglecting or underestimating these uncertainties can easily lead to severe misinterpretations, gross overestimates of the age spread, and ill-based conclusions about the star formation history. These effects are illustrated by means of Monte-Carlo simulations of observed star clusters with realistic observational uncertainties. The most important points are as follows. First, the observed scatter in the HRD must not be confused with a genuine age spread, but is always just an upper limit to the true age spread. Second, histograms of isochronal ages naturally show a

  20. Evaluating the performance of the Lee-Carter method and its variants in modelling and forecasting Malaysian mortality

    Science.gov (United States)

    Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

    2014-12-01

    This study investigated the performance of the Lee-Carter (LC) method and it variants in modeling and forecasting Malaysia mortality. These include the original LC, the Lee-Miller (LM) variant and the Booth-Maindonald-Smith (BMS) variant. These methods were evaluated using Malaysia's mortality data which was measured based on age specific death rates (ASDR) for 1971 to 2009 for overall population while those for 1980-2009 were used in separate models for male and female population. The performance of the variants has been examined in term of the goodness of fit of the models and forecasting accuracy. Comparison was made based on several criteria namely, mean square error (MSE), root mean square error (RMSE), mean absolute deviation (MAD) and mean absolute percentage error (MAPE). The results indicate that BMS method was outperformed in in-sample fitting for overall population and when the models were fitted separately for male and female population. However, in the case of out-sample forecast accuracy, BMS method only best when the data were fitted to overall population. When the data were fitted separately for male and female, LCnone performed better for male population and LM method is good for female population.

  1. Analyses and optimization of Lee propagation model for LoRa 868 MHz network deployments in urban areas

    Directory of Open Access Journals (Sweden)

    Dobrilović Dalibor

    2017-01-01

    Full Text Available In the recent period, fast ICT expansion and rapid appearance of new technologies raised the importance of fast and accurate planning and deployment of emerging communication technologies, especially wireless ones. In this paper is analyzed possible usage of Lee propagation model for planning, design and management of networks based on LoRa 868MHz technology. LoRa is wireless technology which can be deployed in various Internet of Things and Smart City scenarios in urban areas. The analyses are based on comparison of field measurements with model calculations. Besides the analyses of Lee propagation model usability, the possible optimization of the model is discussed as well. The research results can be used for accurate design, planning and for preparation of high-performance wireless resource management of various Internet of Things and Smart City applications in urban areas based on LoRa or similar wireless technology. The equipment used for measurements is based on open-source hardware.

  2. Tentative identification of polar and mid-polar compounds in extracts from wine lees by liquid chromatography-tandem mass spectrometry in high-resolution mode.

    Science.gov (United States)

    Delgado de la Torre, M P; Priego-Capote, F; Luque de Castro, M D

    2015-06-01

    Sustainable agriculture has a pending goal in the revalorization of agrofood residues. Wine lees are an abundant residue in the oenological industry. This residue, so far, has been used to obtain tartaric acid or pigments but not for being qualitatively characterized as a source of polar and mid-polar compounds such as flavonoids, phenols and essential amino acids. Lees extracts from 11 Spanish wineries have been analyzed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) in high resolution mode. The high-resolution power of LC-MS/MS has led to the tentative identification of the most representative compounds present in wine lees, comprising primary amino acids, anthocyans, flavanols, flavonols, flavones and non-flavonoid phenolic compounds, among others. Attending to the profile and content of polar and mid-polar compounds in wine lees, this study underlines the potential of wine lees as an exploitable source to isolate interesting compounds. Copyright © 2015 John Wiley & Sons, Ltd.

  3. Grey relational analysis for evaluating the effects of different rates of wine lees-derived biochar application on a plant-soil system with multi-metal contamination.

    Science.gov (United States)

    Xu, Min; Zhu, Qihong; Wu, Jun; He, Yan; Yang, Gang; Zhang, Xiaohong; Li, Li; Yu, Xiaoyu; Peng, Hong; Wang, Lilin

    2018-03-01

    In this study, grey relational analysis (GRA) was used to investigate the effects of different application rates of wine lees-derived biochar on a plant-soil system with multi-metal contamination. A pot experiment was conducted to determine rice growth in multi-metal-contaminated soil amended with samples of wine lees-derived biochar, and 47 indicators (including soil properties, microbial activity, and plant physiology) were selected as evaluation indexes to assess the plant-soil system. The results indicated that higher wine lees-derived biochar application rates (2% W/W) were favorable for soil fertility, the bioconcentration factor (BF), and the mobility factor (MF, %) (with the exception of Cr, Zn, and Hg), but an application of 1% produced the highest plant growth, enzymatic activities, and bacterial diversity. The richness of the bacterial communities was reduced in the soil amended with the wine lees-derived biochar. According to the GRA assessment, the 1% application rate of wine lees-derived biochar was more suitable for restoring the holistic plant-soil system than were the application rates of 0, 0.5, and 2% (W/W). Furthermore, this study shows that GRA is a useful method for evaluating plant-soil systems.

  4. Use of a Routh-Russel deformation map to achieve film formation of a latex with a high glass transition temperature.

    Science.gov (United States)

    Gonzalez, Edurne; Paulis, María; Barandiaran, María Jesús; Keddie, Joseph L

    2013-02-12

    In the film formation of latex, particle deformation can occur by processes of wet sintering, dry sintering, or capillary action. When latex films dry nonuniformly and when particles deform and coalesce while the film is still wet, a detrimental skin layer will develop at the film surface. In their process model, Routh and Russel proposed that the operative particle deformation mechanism can be determined by the values of control parameters on a deformation map. Here, the film formation processes of three methyl methacrylate/butyl acrylate copolymer latexes with high glass transition temperatures (T(g)), ranging from 45 to 64 °C, have been studied when heated by infrared radiation. Adjusting the infrared (IR) power density enables the film temperature, polymer viscosity, and evaporation rate during latex film formation to be controlled precisely. Different polymer particle deformation mechanisms have been demonstrated for the same latex under a variety of film formation process conditions. When the temperature is too high, a skin layer develops. On the other hand, when the temperature is too low, particles deform by dry sintering, and the process requires extended time periods. The deduced mechanisms can be interpreted and explained by the Routh-Russel deformation maps. Film formation of hard (high T(g)) coatings is achieved without using coalescing aids that emit volatile organic compounds (VOCs), which is a significant technical achievement.

  5. « Russell Banks goes Creole » : A Talk with the Author of The Book of Jamaica and Continental Drift

    Directory of Open Access Journals (Sweden)

    Kathleen Gyssels et Gaëlle Cooreman

    2008-05-01

    Full Text Available Cette interview avec Russell Banks, auteur consacré de notamment The Book of Jamaica (1980 et Continental Drift (1985, tous deux traduits en français chez Actes Sud, a été menée le 27 mai 2007 par Kathleen Gyssels et Gaëlle Cooreman (Université d’Anvers. Elles interrogent Banks sur son idée du Great American Novel, son engagement vis-à-vis de la diaspora africaine et ses romans « caribéens », The Book of Jamaica et Continental Drift.This interview with Russell Banks, acknowledged author of The Book of Jamaica (1980 and Continental Drift (1985, amongst others, was conducted on May 27th 2007 by Kathleen Gyssels and Gaëlle Cooreman (University of Antwerp. The main topics included are Banks’ idea of the Great American Novel, his involvement with the African diaspora and his « Caribbean » novels The Book of Jamaica and Continental Drift.

  6. 12q14 microdeletion syndrome: A family with short stature and Silver-Russell syndrome (SRS)-like phenotype and review of the literature.

    Science.gov (United States)

    Heldt, Frederik; Wallaschek, Hannah; Ripperger, Tim; Morlot, Susanne; Illig, Thomas; Eggermann, Thomas; Schlegelberger, Brigitte; Scholz, Caroline; Steinemann, Doris

    2018-03-01

    We report here on the first family with short stature and Silver-Russell-like phenotype due to a microdeletion in 12q14.3. The Netchine-Harbison clinical scoring system was used for the clinical diagnosis of Silver-Russell syndrome (SRS). The three affected first-degree relatives (index patient, mother and brother) presented with prenatal and postnatal growth retardation, feeding difficulties, a prominent forehead and a failure to thrive, but did not show relative macrocephaly. In addition, our index patient showed dysmorphic facial features, periodically increased sweating, and scoliosis. Learning problems and cardiac arrhythmia presented as additional features of her brother. Using high-resolution array-CGH, heterozygosity for a 1.67 Mb deletion in 12q14.3 was detected in the index patient. The heterozygous loss was confirmed by MLPA in the index patient and the other two affected family members. The deletion includes the genes HMGA2, LLPH, TMBIM4, IRAK3, HELB, GRIP1, and the pseudogene RPSAP52. We conclude from these results and from the data of other patients reported in the literature that haploinsufficiency of HMGA2 leads to the short stature in this family. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  7. NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxide.

    Directory of Open Access Journals (Sweden)

    Priscilla Branchu

    2014-01-01

    Full Text Available Expression of genes of the locus of enterocyte effacement (LEE is essential for adherence of enterohemorrhagic Escherichia coli (EHEC to intestinal epithelial cells. Gut factors that may modulate LEE gene expression may therefore influence the outcome of the infection. Because nitric oxide (NO is a critical effector of the intestinal immune response that may induce transcriptional regulation in enterobacteria, we investigated its influence on LEE expression in EHEC O157:H7. We demonstrate that NO inhibits the expression of genes belonging to LEE1, LEE4, and LEE5 operons, and that the NO sensor nitrite-sensitive repressor (NsrR is a positive regulator of these operons by interacting directly with the RNA polymerase complex. In the presence of NO, NsrR detaches from the LEE1/4/5 promoter regions and does not activate transcription. In parallel, two regulators of the acid resistance pathway, GadE and GadX, are induced by NO through an indirect NsrR-dependent mechanism. In this context, we show that the NO-dependent LEE1 down-regulation is due to absence of NsrR-mediated activation and to the repressor effect of GadX. Moreover, the inhibition of expression of LEE4 and LEE5 by NO is due to loss of NsrR-mediated activation, to LEE1 down-regulation and to GadE up-regulation. Lastly, we establish that chemical or cellular sources of NO inhibit the adherence of EHEC to human intestinal epithelial cells. These results highlight the critical effect of NsrR in the regulation of the LEE pathogenicity island and the potential role of NO in the limitation of colonization by EHEC.

  8. Brown trout in the Lees Ferry reach of the Colorado River—Evaluation of causal hypotheses and potential interventions

    Science.gov (United States)

    Runge, Michael C.; Yackulic, Charles B.; Bair, Lucas S.; Kennedy, Theodore A.; Valdez, Richard A.; Ellsworth, Craig; Kershner, Jeffrey L.; Rogers, R. Scott; Trammell, Melissa A.; Young, Kirk L.

    2018-04-17

    Over the period 2014–2016, the number of nonnative brown trout (Salmo trutta) captured during routine monitoring in the Lees Ferry reach of the Colorado River, downstream of Glen Canyon Dam, began increasing. Management agencies and stakeholders have questioned whether the increase in brown trout in the Lees Ferry reach represents a threat to the endangered humpback chub (Gila cypha), to the rainbow trout (Oncorhynchus mykiss) sport fishery, or to other resources of concern. In this report, we evaluate the evidence for the expansion of brown trout in the Lees Ferry reach, consider a range of causal hypotheses for this expansion, examine the likely efficacy of several potential management interventions to reduce brown trout, and analyze the effects of those interventions on other resources of concern.The brown trout population at Lees Ferry historically consisted of a small number of large fish supported by low levels of immigration from downstream reaches. This population is now showing signs of sustained successful reproduction and is on the cusp of recruiting locally hatched fish into the spawning class, based on analysis with a new integrated population model. The proximate causes of this change in status are a large pulse of immigration in the fall of 2014 and higher reproductive rates in 2015–2017. The ultimate causes of this change are not clear. The pulse of immigrants from downstream reaches in fall 2014 may have been induced by three sequential high-flow releases from the dam in November of 2012–2014, but may also have been the result of a unique set of circumstances unrelated to dam operations. The increase in reproduction may have been the result of any number of changes, including an Allee effect, warmer water temperatures, a decrease in competition from rainbow trout, or fall high-flow releases. Correlations over space and time among predictor variables do not allow us to make a clear inference about the cause of the changes. Under a null causal

  9. The role of upper tropospheric jet streaks and lee-side cyclogenesis in the development of low level jets in the great plains

    Science.gov (United States)

    Uccellini, L. W.

    1980-01-01

    A review of 15 cases of low level jets (LLJ) which developed in the Great Plains is presented. For 12 out of the 15 cases, a systematic upper level flow pattern was isolated which includes the existence of a trough over the southwest United States and the propagation of upper level jet streaks from the Rocky Mountains toward the Great Plains. This flow pattern is responsible for lee side cyclogenesis or lee side troughing that produces the pressure gradients needed for the development of the LLJ. For the other three cases, a blocking ridge existed over the Great Plains and the upper level flow is relatively weak. It is during these situations that the classic, diurnal oscillating LLJ was observed. A more detailed review of four cases indicates that the subsynoptic scale adjustments associated with the upper level jet streak's forcing of lee side cyclogenesis could be an important factor in the development of LLJ's in the Great Plains.

  10. Book Review: Drexl, J., Lee, N. (2013). Pharmaceutical Innovation, Competition and Patent Law : A Trilateral Perspective. Edward Elgar Publishing

    DEFF Research Database (Denmark)

    Minssen, Timo

    2014-01-01

    aspects of “Pharmaceutical Innovation, Competition and Patent Law”. It provides valuable analyses of the fundamental challenges that the pharmaceutical sector encounters on both a global and regional level. The editors and authors have thus compiled an important publication that will provide stimulation......This is a review of the recent publication “Pharmaceutical Innovation, Competition and Patent Law – A Trilateral Perspective”, edited by Max Planck Director Josef Drexl and Finnish scholar Nari Lee (Edward Elgar 2013, 322 p., ISBN 978 0 85793 245 7). In summary, I conclude that the editors, who...... of recent developments that have such a substantial impact on a significant area of law and practice. But are there any flaws? Considering the numerous useful case law citations, as well as the wide scope of the book, it is a little unfortunate that the book does not contain a table of cases...

  11. Mass elevation and lee effects markedly lift the elevational distribution of ground beetles in the Himalaya-Tibet orogen.

    Science.gov (United States)

    Schmidt, Joachim; Böhner, Jürgen; Brandl, Roland; Opgenoorth, Lars

    2017-01-01

    Mass elevation and lee effects markedly influence snow lines and tree lines in high mountain systems. However, their impact on other phenomena or groups of organisms has not yet been quantified. Here we quantitatively studied their influence in the Himalaya-Tibet orogen on the distribution of ground beetles as model organisms, specifically whether the ground beetle distribution increases from the outer to the inner parts of the orogen, against latitudinal effects. We also tested whether July temperature and solar radiation are predictors of the beetle's elevational distribution ranges. Finally, we discussed the general importance of these effects for the distributional and evolutionary history of the biota of High Asia. We modelled spatially explicit estimates of variables characterizing temperature and solar radiation and correlated the variables with the respective lower elevational range of 118 species of ground beetles from 76 high-alpine locations. Both July temperature and solar radiation significantly positively correlated with the elevational ranges of high-alpine beetles. Against the latitudinal trend, the median elevation of the respective species distributions increased by 800 m from the Himalayan south face north to the Transhimalaya. Our results indicate that an increase in seasonal temperature due to mass elevation and lee effects substantially impact the regional distribution patterns of alpine ground beetles of the Himalaya-Tibet orogen and are likely to affect also other soil biota there and in mountain ranges worldwide. Since these effects must have changed during orogenesis, their potential impact must be considered when biogeographic scenarios based on geological models are derived. As this has not been the practice, we believe that large biases likely exist in many paleoecological and evolutionary studies dealing with the biota from the Himalaya-Tibet orogen and mountain ranges worldwide.

  12. Estudio clínico, citogenético y molecular en pacientes con el síndrome de Russell- Silver

    Directory of Open Access Journals (Sweden)

    Gabriel Bedoya Berrío

    2001-04-01

    Full Text Available El síndrome de Russel Silver (SRS fue descrito independientemente por Silver y colaboradores en 1953 (1 y por Russell en 1954 (2. Silver hizo énfasis en la asimetría esquelética como característica del trastorno. Russel observó que esta característica era variable en los pacientes que examinó. El diagnóstico clínico incluye un severo retraso en el crecimiento pre y postnatal, características dismórficas incluyendo cara triangular, frente amplia, mandíbula pequeña y comisuras
    labiales hacia abajo (3,4.
    Recientes descubrimientos de disomía uniparental materna
    (DUPm del cromosoma 7 en el 10% de los pacientes con SRS,
    sugieren la presencia de genes impronta en este cromosoma, cuya mutación es responsable del fenotipo de SRS (5.
    Genes comprometidos: varios genes impronta (PEG1/MEST,
    gamama2- COP, y GBR10 localizados en el cromosoma 7. En pacientes con SRS se han identificado duplicaciones en la región 7p13-p11.2 de origen materno que rodean el gen GBR10. Recientemente, pacientes SRS con DUP de la región 7q31-qter únicamente, han reforzado la evidencia que PG1/MEST o genes adyacentes son críticos.
    Pruebas moleculares: solamente el 10% de los casos clínicos
    presentan un mecanismo de alteración de la impronta (UDPm 7; este análisis de microsatélites requiere las muestras de los padres. Luego de que los genes críticos han sido mapeados, las deleciones y los puntos de mutación pueden identificarse en pacientes que no presentan DUP (6.
    La incidencia de SRS no se conoce y puede estar subestimada.

  13. W3C director Tim Berners-Lee to be Knighted by Queen Elizabeth web inventor recognized for contributions to internet development

    CERN Document Server

    2003-01-01

    "Tim Berners-Lee, the inventor of the World Wide Web and director of the World Wide Web Consortium (W3C), will be made a Knight Commander, Order of the British Empire (KBE) by Queen Elizabeth" (1/2 page).

  14. The NAG Sensor NagC Regulates LEE Gene Expression and Contributes to Gut Colonization by Escherichia coli O157:H7

    Directory of Open Access Journals (Sweden)

    Josée Harel

    2017-04-01

    Full Text Available Enterohemorrhagic Escherichia coli (EHEC O157:H7 are human pathogens responsible for bloody diarrhea and renal failures. EHEC employ a type 3 secretion system to attach directly to the human colonic epithelium. This structure is encoded by the locus of enterocyte effacement (LEE whose expression is regulated in response to specific nutrients. In this study, we show that the mucin-derived sugars N-acetylglucosamine (NAG and N-acetylneuraminic acid (NANA inhibit EHEC adhesion to epithelial cells through down-regulation of LEE expression. The effect of NAG and NANA is dependent on NagC, a transcriptional repressor of the NAG catabolism in E. coli. We show that NagC is an activator of the LEE1 operon and a critical regulator for the colonization of mice intestine by EHEC. Finally, we demonstrate that NAG and NANA as well as the metabolic activity of Bacteroides thetaiotaomicron affect the in vivo fitness of EHEC in a NagC-dependent manner. This study highlights the role of NagC in coordinating metabolism and LEE expression in EHEC and in promoting EHEC colonization in vivo.

  15. The Effects of Input Enhancement on Grammar Learning and Comprehension: A Modified Replication of Lee (2007) with Eye-Movement Data

    Science.gov (United States)

    Winke, Paula M.

    2013-01-01

    In his 2007 study "Effects of Textual Enhancement and Topic Familiarity on Korean EFL Students' Reading Comprehension and Learning of Passive Form," Lee demonstrated that learners were better able to correct written sentences that contained incorrect English passive forms after exposure to texts flooded with enhanced (versus…

  16. Hypomethylation of the H19 Gene Causes Not Only Silver-Russell Syndrome (SRS) but Also Isolated Asymmetry or an SRS-Like Phenotype

    Science.gov (United States)

    Bliek, Jet; Terhal, Paulien; van den Bogaard, Marie-José; Maas, Saskia; Hamel, Ben; Salieb-Beugelaar, Georgette; Simon, Marleen; Letteboer, Tom; van der Smagt, Jasper; Kroes, Hester; Mannens, Marcel

    2006-01-01

    The H19 differentially methylated region (DMR) controls the allele-specific expression of both the imprinted H19 tumor-suppressor gene and the IGF2 growth factor. Hypermethylation of this DMR—and subsequently of the H19 promoter region—is a major cause of the clinical features of gigantism and/or asymmetry seen in Beckwith-Wiedemann syndrome or in isolated hemihypertrophy. Here, we report a series of patients with hypomethylation of the H19 locus. Their main clinical features of asymmetry and growth retardation are the opposite of those seen in patients with hypermethylation of this region. In addition, we show that complete hypomethylation of the H19 promoter is found in two of three patients with the full clinical spectrum of Silver-Russell syndrome. This syndrome is also characterized by growth retardation and asymmetry, among other clinical features. We conclude that patients with these clinical features should be analyzed for H19 hypomethylation. PMID:16532391

  17. Attaching and effacing (A/E) lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors.

    Science.gov (United States)

    Cepeda-Molero, Massiel; Berger, Cedric N; Walsham, Alistair D S; Ellis, Samuel J; Wemyss-Holden, Simon; Schüller, Stephanie; Frankel, Gad; Fernández, Luis Ángel

    2017-10-01

    Enteropathogenic E. coli (EPEC) is a human pathogen that causes acute and chronic pediatric diarrhea. The hallmark of EPEC infection is the formation of attaching and effacing (A/E) lesions in the intestinal epithelium. Formation of A/E lesions is mediated by genes located on the pathogenicity island locus of enterocyte effacement (LEE), which encode the adhesin intimin, a type III secretion system (T3SS) and six effectors, including the essential translocated intimin receptor (Tir). Seventeen additional effectors are encoded by genes located outside the LEE, in insertion elements and prophages. Here, using a stepwise approach, we generated an EPEC mutant lacking the entire effector genes (EPEC0) and intermediate mutants. We show that EPEC0 contains a functional T3SS. An EPEC mutant expressing intimin but lacking all the LEE effectors but Tir (EPEC1) was able to trigger robust actin polymerization in HeLa cells and mucin-producing intestinal LS174T cells. However, EPEC1 was unable to form A/E lesions on human intestinal in vitro organ cultures (IVOC). Screening the intermediate mutants for genes involved in A/E lesion formation on IVOC revealed that strains lacking non-LEE effector/s have a marginal ability to form A/E lesions. Furthermore, we found that Efa1/LifA proteins are important for A/E lesion formation efficiency in EPEC strains lacking multiple effectors. Taken together, these results demonstrate the intricate relationships between T3SS effectors and the essential role non-LEE effectors play in A/E lesion formation on mucosal surfaces.

  18. Attaching and effacing (A/E lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors.

    Directory of Open Access Journals (Sweden)

    Massiel Cepeda-Molero

    2017-10-01

    Full Text Available Enteropathogenic E. coli (EPEC is a human pathogen that causes acute and chronic pediatric diarrhea. The hallmark of EPEC infection is the formation of attaching and effacing (A/E lesions in the intestinal epithelium. Formation of A/E lesions is mediated by genes located on the pathogenicity island locus of enterocyte effacement (LEE, which encode the adhesin intimin, a type III secretion system (T3SS and six effectors, including the essential translocated intimin receptor (Tir. Seventeen additional effectors are encoded by genes located outside the LEE, in insertion elements and prophages. Here, using a stepwise approach, we generated an EPEC mutant lacking the entire effector genes (EPEC0 and intermediate mutants. We show that EPEC0 contains a functional T3SS. An EPEC mutant expressing intimin but lacking all the LEE effectors but Tir (EPEC1 was able to trigger robust actin polymerization in HeLa cells and mucin-producing intestinal LS174T cells. However, EPEC1 was unable to form A/E lesions on human intestinal in vitro organ cultures (IVOC. Screening the intermediate mutants for genes involved in A/E lesion formation on IVOC revealed that strains lacking non-LEE effector/s have a marginal ability to form A/E lesions. Furthermore, we found that Efa1/LifA proteins are important for A/E lesion formation efficiency in EPEC strains lacking multiple effectors. Taken together, these results demonstrate the intricate relationships between T3SS effectors and the essential role non-LEE effectors play in A/E lesion formation on mucosal surfaces.

  19. The Effect of Selected Cleaning Techniques on Berkshire Lee Marble: A Scientific Study at Philadelphia City Hall

    Science.gov (United States)

    Mossotti, Victor G.; Eldeeb, A. Raouf; Fries, Terry L.; Coombs, Mary Jane; Naude, Virginia N.; Soderberg, Lisa; Wheeler, George S.

    2002-01-01

    This report describes a scientific investigation of the effects of eight different cleaning techniques on the Berkshire Lee marble component of the facade of the East Center Pavilion at Philadelphia City Hall; the study was commissioned by the city of Philadelphia. The eight cleaning techniques evaluated in this study were power wash (proprietary gel detergent followed by water rinse under pressure), misting (treatment with potable, nebulized water for 24-36 hours), gommage (proprietary Thomann-Hanry low-pressure, air-driven, small-particle, dry abrasion), combination (gommage followed by misting), Armax (sodium bicarbonate delivered under pressure in a water wash), JOS (dolomite powder delivered in a low-pressure, rotary-vortex water wash), laser (thermal ablation), and dry ice (powdered-dry-ice abrasion delivered under pressure). In our study approximately 160 cores were removed from the building for laboratory analysis. We developed a computer program to analyze scanning-electron-micrograph images for the microscale surface roughness and other morphologic parameters of the stone surface, including the near-surface fracture density of the stone. An analysis of more than 1,100 samples cut from the cores provided a statistical basis for crafting the essential elements of a reduced-form, mixed-kinetics conceptual model that represents the deterioration of calcareous stone in terms of self-organized soiling and erosion patterns. This model, in turn, provided a basis for identifying the variables that are affected by the cleaning techniques and for evaluating the extent to which such variables influence the stability of the stone. The model recognizes three classes of variables that may influence the soiling load on the stone, including such exogenous environmental variables as airborne moisture, pollutant concentrations, and local aerodynamics, and such endogenous stone variables as surface chemistry and microstructure (fracturing, roughness, and so on). This study

  20. Social networks and inference about unknown events: A case of the match between Google's AlphaGo and Sedol Lee.

    Directory of Open Access Journals (Sweden)

    Jonghoon Bae

    Full Text Available This study examines whether the way that a person makes inferences about unknown events is associated with his or her social relations, more precisely, those characterized by ego network density that reflects the structure of a person's immediate social relation. From the analysis of individual predictions over the Go match between AlphaGo and Sedol Lee in March 2016 in Seoul, Korea, this study shows that the low-density group scored higher than the high-density group in the accuracy of the prediction over a future state of a social event, i.e., the outcome of the first game. We corroborated this finding with three replication tests that asked the participants to predict the following: film awards, President Park's impeachment in Korea, and the counterfactual assessment of the US presidential election. Taken together, this study suggests that network density is negatively associated with vision advantage, i.e., the ability to discover and forecast an unknown aspect of a social event.

  1. Lee Sang Gak Telescope (LSGT): A Remotely Operated Robotic Telescope for Education and Research at Seoul National University

    Science.gov (United States)

    Im, Myungshin; Choi, Changsu; Kim, Kihyun

    2015-08-01

    We introduce the Lee Sang Gak Telescope (LSGT), a remotely operated, robotic 0.43-meter telescope. The telescope was installed at the Siding Spring Observatory, Australia, in 2014 October, to secure regular and exclusive access to the dark sky and excellent atmospheric conditions in the southern hemisphere from the Seoul National University (SNU) campus. Here, we describe the LSGT system and its performance, present example images from early observations, and discuss a future plan to upgrade the system. The use of the telescope includes (i) long-term monitoring observations of nearby galaxies, active galactic nuclei, and supernovae; (ii) rapid follow-up observations of transients such as gamma-ray bursts and gravitational wave sources; and (iii) observations for educational activities at SNU. Based on observations performed so far, we find that the telescope is capable of providing images to a depth of R=21.5 mag (point source detection) at 5-σ with 15 min total integration time under good obs-erving conditions.

  2. Economic value of angling on the Colorado River at Lees Ferry: Using secondary data to estimate the influence of seasonality

    Science.gov (United States)

    Bair, Lucas S.; Rogowski, David L.; Neher, Christopher

    2016-01-01

    Glen Canyon Dam (GCD) on the Colorado River in northern Arizona provides water storage, flood control, and power system benefits to approximately 40 million people who rely on water and energy resources in the Colorado River basin. Downstream resources (e.g., angling, whitewater floating) in Glen Canyon National Recreation Area (GCNRA) and Grand Canyon National Park are impacted by the operation of GCD. The GCD Adaptive Management Program was established in 1997 to monitor and research the effects of dam operations on the downstream environment. We utilized secondary survey data and an individual observation travel cost model to estimate the net economic benefit of angling in GCNRA for each season and each type of angler. As expected, the demand for angling decreased with increasing travel cost; the annual value of angling at Lees Ferry totaled US$2.7 million at 2014 visitation levels. Demand for angling was also affected by season, with per-trip values of $210 in the summer, $237 in the spring, $261 in the fall, and $399 in the winter. This information provides insight into the ways in which anglers are potentially impacted by seasonal GCD operations and adaptive management experiments aimed at improving downstream resource conditions.

  3. The contributions of Donald Lee Johnson to understanding the Quaternary geologic and biogeographic history of the California Channel Islands

    Science.gov (United States)

    Muhs, Daniel R.

    2013-01-01

    Over a span of 50 years, native Californian Donald Lee Johnson made a number of memorable contributions to our understanding of the California Channel Islands. Among these are (1) recognizing that carbonate dunes, often cemented into eolianite and derived from offshore shelf sediments during lowered sea level, are markers of glacial periods on the Channel Islands; (2) identifying beach rock on the Channel Islands as the northernmost occurrence of this feature on the Pacific Coast of North America; (3) recognizing of the role of human activities in historic landscape modification; (4) identifying both the biogenic and pedogenic origins of caliche “ghost forests” and laminar calcrete forms on the Channel Islands; (5) providing the first soil maps of several of the islands, showing diverse pathways of pedogenesis; (6) pointing out the importance of fire in Quaternary landscape history on the Channel Islands, based on detailed stratigraphic studies; and (7), perhaps his greatest contribution, clarifying the origin of Pleistocene pygmy mammoths on the Channel Islands, due not to imagined ancient land bridges, but rather the superb swimming abilities of proboscideans combined with lowered sea level, favorable paleowinds, and an attractive paleovegetation on the Channel Islands. Don was a classic natural historian in the great tradition of Charles Darwin and George Gaylord Simpson, his role models. Don’s work will remain important and useful for many years and is an inspiration to those researching the California Channel Islands today.

  4. Comparison of total polyphenols content and antioxidant potential of wines from ‘Welschriesling’ and ‘Sauvignon Blanc’ varieties during ageing on fine lees

    Directory of Open Access Journals (Sweden)

    Jasna Lužar

    2016-10-01

    Full Text Available Phenolic compounds are key components of wine, since they contribute to wine characteristics such as colour, astringency and bitterness. They also act like antioxidants, with mechanisms involving free-radical scavenging that could prevent cardiovascular diseases and cancer. The aim of the present work was to compare the obtained results of total polyphenols content and antioxidant potential (AOP of several white wines (welschriesling and sauvignon blanc during ageing on fine lees. The total polyphenols content decreased in average for 16.1 % in welschriesling wines and for 18.7 % in sauvignon blanc wines in the period of three months of wine ageing on lees. In the same period AOP of wines decreased in average for 16.0 % in welschriesling wines and for 8.0 % in sauvignon blanc wines. Expectedly, the samples with added oak chips in grape must had higher antioxidant potential than others.

  5. Modelagem conjunta da média e dispersão de Nelder e Lee como alternativa aos métodos de Taguchi

    Directory of Open Access Journals (Sweden)

    Edmilson Rodrigues Pinto

    2006-08-01

    Full Text Available Nos últimos anos, uma coleção de técnicas para a melhoria da qualidade foi desenvolvida, no Japão, por Genichi Taguchi no planejamento, na evolução e na fabricação de produtos industrializados. Esta revolução no campo da qualidade despertou o interesse, no mundo inteiro, de vários engenheiros e estatísticos, que propuseram vários métodos alternativos, mais claros e eficientes do que aqueles propostos por Taguchi. Nelder e Lee observaram que a metodologia de Taguchi conduz a um modelo conjunto para a média e dispersão, usando modelos lineares generalizados. Eles mostraram como esta classe é geral e suficiente para a análise desses modelos. O objetivo deste artigo é fazer uma síntese da modelagem conjunta da média e dispersão, proposta por Nelder e Lee, explicitando, de uma forma concisa, os principais pontos da teoria.In the last years, in Japan, Genichi Taguchi developed some techniques to improve the quality of the products during its design, evolution and manufacture. His ideas have raised the attention of engineers and statisticians around the world who have proposed some alternative methods that are simpler and more efficient than Taguchi's methods. Nelder and Lee observed that Taguchi's methodology lead up to a joint model for the mean and dispersion employing generalized linear models. They showed that this class is general and sufficient to analyze Taguchi's Models. The purpose of this work is to describe joint modeling of mean and dispersion that was proposed by Nelder and Lee and the key points of the theory in a concise manner.

  6. A Rasch Analysis of Assessments of Morning and Evening Fatigue in Oncology Patients Using the Lee Fatigue Scale.

    Science.gov (United States)

    Lerdal, Anners; Kottorp, Anders; Gay, Caryl; Aouizerat, Bradley E; Lee, Kathryn A; Miaskowski, Christine

    2016-06-01

    To accurately investigate diurnal variations in fatigue, a measure needs to be psychometrically sound and demonstrate stable item function in relationship to time of day. Rasch analysis is a modern psychometric approach that can be used to evaluate these characteristics. To evaluate, using Rasch analysis, the psychometric properties of the Lee Fatigue Scale (LFS) in a sample of oncology patients. The sample comprised 587 patients (mean age 57.3 ± 11.9 years, 80% women) undergoing chemotherapy for breast, gastrointestinal, gynecological, or lung cancer. Patients completed the 13-item LFS within 30 minutes of awakening (i.e., morning fatigue) and before going to bed (i.e., evening fatigue). Rasch analysis was used to assess validity and reliability. In initial analyses of differential item function, eight of the 13 items functioned differently depending on whether the LFS was completed in the morning or in the evening. Subsequent analyses were conducted separately for the morning and evening fatigue assessments. Nine of the morning fatigue items and 10 of the evening fatigue items demonstrated acceptable goodness-of-fit to the Rasch model. Principal components analyses indicated that both morning and evening assessments demonstrated unidimensionality. Person-separation indices indicated that both morning and evening fatigue scales were able to distinguish four distinct strata of fatigue severity. Excluding four items from the morning fatigue scale and three items from the evening fatigue scale improved the psychometric properties of the LFS for assessing diurnal variations in fatigue severity in oncology patients. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  7. Transcriptome analysis of stem development in the tumourous stem mustard Brassica juncea var. tumida Tsen et Lee by RNA sequencing

    Directory of Open Access Journals (Sweden)

    Sun Quan

    2012-04-01

    Full Text Available Abstract Background Tumourous stem mustard (Brassica juncea var. tumida Tsen et Lee is an economically and nutritionally important vegetable crop of the Cruciferae family that also provides the raw material for Fuling mustard. The genetics breeding, physiology, biochemistry and classification of mustards have been extensively studied, but little information is available on tumourous stem mustard at the molecular level. To gain greater insight into the molecular mechanisms underlying stem swelling in this vegetable and to provide additional information for molecular research and breeding, we sequenced the transcriptome of tumourous stem mustard at various stem developmental stages and compared it with that of a mutant variety lacking swollen stems. Results Using Illumina short-read technology with a tag-based digital gene expression (DGE system, we performed de novo transcriptome assembly and gene expression analysis. In our analysis, we assembled genetic information for tumourous stem mustard at various stem developmental stages. In addition, we constructed five DGE libraries, which covered the strains Yong'an and Dayejie at various development stages. Illumina sequencing identified 146,265 unigenes, including 11,245 clusters and 135,020 singletons. The unigenes were subjected to a BLAST search and annotated using the GO and KO databases. We also compared the gene expression profiles of three swollen stem samples with those of two non-swollen stem samples. A total of 1,042 genes with significantly different expression levels occurring simultaneously in the six comparison groups were screened out. Finally, the altered expression levels of a number of randomly selected genes were confirmed by quantitative real-time PCR. Conclusions Our data provide comprehensive gene expression information at the transcriptional level and the first insight into the understanding of the molecular mechanisms and regulatory pathways of stem swelling and development

  8. Reseña Bibliográfica: El significado de la Ética para George Edward Moore, Bertrand Russell, James M. Buchanan y Jürgen Habermas.

    OpenAIRE

    Delvasto P, Carlos Andrés; Pontificia Universidad Javeriana Cali

    2013-01-01

    Esta reseña tiene como propósito comprender el rol de la Ética en diferentes corrientes filosóficas, tomando como punto de referencia las obras George Edward Moore, Bertrand Russell, James M. Buchanan y Jürgen Habermas, al igual que vislumbrar la tarea de esta en el proceso de cambio social que urge llevar a cabo en nuestra sociedad.

  9. Staarkleidid / Lee Hanael

    Index Scriptorium Estoniae

    Hanael, Lee

    2008-01-01

    10 maailma kuulsamat kleiti kuulusid Marilyn Monroele, Audrey Hepburnile, printsess Dianale, Vivien Leighle, Tina Turnerile, Julia Robertsile, Liz Hurleyle, Sarah Jessica Parkerile, Keira Knightleyle, Jacqueline Kennedyle

  10. HYDROLOGY, LEE COUNTY, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a Flood Insurance...

  11. HYDRAULICS, LEE COUNTY, MISSISSIPPI

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  12. HYDROLOGY, LEE COUNTY, MISSISSIPPI

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  13. Erasmusega Eestisse / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2014-01-01

    Prantsuse noormees Théo Brunie õppis Lumière’i ülikoolis Lyonis kommunikatsiooni. Aasta Erasmuse vahetusüliõpilasena Balti Filmi- ja Meediakoolis kasutas ta võimalust õppida kommunikatsiooni koos filmitegemisega

  14. Lee Nnukwu Ukochukwu

    African Journals Online (AJOL)

    User

    Another form of it has more verses sung in the exact fashion as the first. Kpakpando na-amuke and Nni ndi ... A general trend of harmonizing only the chorus or refrain is observed. Only a few works have harmonized .... Something that looks like a second development begins in bar nine. It is a descending move from the ...

  15. Extraordinary claims require extraordinary evidence: C.H. Payne H.N. Russell and standards of evidence in early quantitative spectroscopy

    Science.gov (United States)

    Devorkin, David H.

    2010-07-01

    The ionization equilibrium theory of Meghnad Saha was hardly four years old, and still far from general acceptance, when a graduate student at Harvard University, Cecilia H. Payne, applied it to calibrate the Harvard spectral sequence as a temperature sequence. Payne indeed utilized Saha's relation not in its original form, but in its more acceptable form based upon a statistical mechanical re-derivation by E.A. Milne and R.H. Fowler. Her temperature calibration was, therefore, not at issue for her mentors at Harvard, such as Harlow Shapley, and her external reviewer for her Ph.D., Shapley's former teacher, the influential Princeton astronomer, Henry Norris Russell. Other conclusions she drew from her analysis, moreover, went beyond the evidence, they felt, and so she had to moderate her most provocative finding: that hydrogen dominated the atmospheres of the stars. She did so, however, in a manner that was designed to record for posterity that she was the first to make this observation, right or wrong. In so doing, Payne can be credited with profound political acumen, a quality that deserves more attention in the history of twentieth century astronomy.

  16. Resister's logic: the anti-vaccination arguments of Alfred Russel Wallace and their role in the debates over compulsory vaccination in England, 1870-1907.

    Science.gov (United States)

    Fichman, Martin; Keelan, Jennifer E

    2007-09-01

    In the 1880s, Alfred Russel Wallace, the celebrated co-discoverer of natural selection, launched himself into the centre of a politicised and polarised debate over the unpopular compulsory vaccination laws in England. Wallace never wavered in his belief that smallpox vaccination was useless and likely dangerous. Six years before his death, the anti-vaccinationists successfully secured a conscience clause that effectively dismantled the compulsory vaccination laws. Several other important Victorian scientists joined Wallace in the fight to repeal compulsory vaccination arguing that widely held views on the effectiveness of vaccination and evidence for immunity were inconclusive in the light of (then) contemporary standards of evidence. This article situates Wallace's anti-vaccination logic within the broader matrix of sociopolitical and cultural reform movements of the late Victorian era. Additionally it provides the first detailed analysis of his critique of vaccination science, in particular the role statistics played in his arguments. In this period, both pro-vaccinationists and anti-vaccinationists invested great efforts in collating and analysing statistical data sets that either supported or refuted the claims of vaccination's effectiveness. While each side presented 'controlled' case studies to support their assertions, without an unambiguous test to measure or demonstrate vaccination's effectiveness, the anti-vaccinationists continued to mount credible statistical critiques of vaccination science.

  17. Influence of Constant Temperature on Development and Reproduction of Encarsia guadeloupae Viggiani (Hymenoptera: Aphelinidae), a Parasitoid of the Spiraling Whitefly Aleurodicus dispersus Russell (Hemiptera: Aleyrodidae).

    Science.gov (United States)

    Chen, J Y; Niu, L M; Li, L; Han, D Y; Fu, Y G

    2015-04-01

    Encarsia guadeloupae Viggiani is an important parasitoid of Aleurodicus dispersus Russell. The effects of temperature (16, 20, 24, 28, and 32°C) on development and reproduction of this parasitoid on A. dispersus were studied in laboratory experiments. The developmental duration of E. guadeloupae varied from 14.9 (32°C) to 54.4 days (16°C). The developmental threshold and thermal constant for an entire generation were 10.52°C and 308.85 degree-days, respectively. The highest survival rate (63.8%) of immature E. guadeloupae was recorded at 28°C. The average adult longevity ranged from 6.0 (32°C) to 15.1 days (16°C). The highest fecundity was observed at 28°C. The intrinsic rate of increase (r m ), net reproduction rate (R o ), and finite rate of increase (λ) were the highest at 28°C, which were 0.18, 54.25 and 1.21, respectively. We concluded that 28°C is the most suitable temperature for development and reproduction of E. guadeloupae.

  18. Thin-layer effects in glaciological seismic amplitude-versus-angle (AVA) analysis: implications for characterising a subglacial till unit, Russell Glacier, West Greenland

    Science.gov (United States)

    Booth, A. D.; Clark, R. A.; Kulessa, B.; Murray, T.; Hubbard, A.

    2012-02-01

    Seismic amplitude-versus-angle (AVA) methods are a powerful means of interpreting the physical properties of subglacial material, although interpreting an AVA response is complicated in the case of a thinly-layered substrate. A layer thinner than one-quarter of the seismic wavelength is considered seismically "thin", and reflections from its bounding interfaces are perceived as a single event. Since a lodged (non-deforming) subglacial till can capped by a thin (metre-scale) cap of dilatant (deforming) till, serious misinterpretations can result if thin layer considerations are not honoured. AVA responses for layered subglacial tills are simulated: we model dilatant layers of thickness 0.1-3.0 m (up to a quarter-wavelength of our synthetic seismic pulse) overlying a lodged half-space, assigning typical acoustic impedance and Poisson's ratios to each. If thin layer effects are neglected, the AVA response to ultra-thin (AVA response. We apply this method to example seismic AVA data from the Russell Glacier outlet of the West Greenland Ice Sheet, in which characteristics of thin layer responses are evident. We interpret a stratified subglacial deposit, with upper and lower layers of high-porosity (0.492 ± 0.015) and low-porosity (acoustic impedance of 4.20-4.39 × 106 kg m-2 s-1) material, respectively assumed to represent dilatant and lodged tills. Thin layer considerations are strongly advised wherever seismic AVA analyses are used to quantify subglacial material properties.

  19. Comparative study of anticoagulant and procoagulant properties of 28 snake venoms from families Elapidae, Viperidae, and purified Russell's viper venom-factor X activator (RVV-X).

    Science.gov (United States)

    Suntravat, Montamas; Nuchprayoon, Issarang; Pérez, John C

    2010-09-15

    Snake venoms consist of numerous molecules with diverse biological functions used for capturing prey. Each component of venom has a specific target, and alters the biological function of its target. Once these molecules are identified, characterized, and cloned; they could have medical applications. The activated clotting time (ACT) and clot rate were used for screening procoagulant and anticoagulant properties of 28 snake venoms. Crude venoms from Daboia russellii siamensis, Bothrops asper, Bothrops moojeni, and one Crotalus oreganus helleri from Wrightwood, CA, had procoagulant activity. These venoms induced a significant shortening of the ACT and showed a significant increase in the clot rate when compared to the negative control. Factor X activator activity was also measured in 28 venoms, and D. r. siamensis venom was 5-6 times higher than those of B. asper, B. moojeni, and C. o. helleri from Wrightwood County. Russell's viper venom-factor X activator (RVV-X) was purified from D. r. siamensis venom, and then procoagulant activity was evaluated by the ACT and clot rate. Other venoms, Crotalus atrox and two Naja pallida, had anticoagulant activity. A significant increase in the ACT and a significant decrease in the clot rate were observed after the addition of these venoms; therefore, the venoms were considered to have anticoagulant activity. Venoms from the same species did not always have the same ACT and clot rate profiles, but the profiles were an excellent way to identify procoagulant and anticoagulant activities in snake venoms.

  20. Numerical experiments on plasma focus for soft x-ray yield scaling laws derivation using Lee model

    International Nuclear Information System (INIS)

    Akel, M.

    2012-09-01

    The required plasma parameters of krypton and xenon at different temperatures were calculated, the x-ray emission properties of plasmas were studied, and based on the corona model the suitable temperature range for generating H-like and He-like ions (therefore soft x-ray emissions) of different gases plasma were found. The code is applied to characterize the plasma focus in different plasma focus devices, and for optimizing the nitrogen, oxygen, neon, argon, krypton and xenon soft x-ray yields based on bank, tubes and operating parameters. It is found that the soft x-ray yield increases with changing pressure until it reaches the maximum value for each plasma focus device. Keeping the bank parameters, operational voltage unchanged but systematically changing other parameters, numerical experiments were performed finding the optimum combination of P o , Z o and 'a' for the maximum soft x-ray yield. Thus we expect to increase the soft x-ray yield of plasma focus device several-fold from its present typical operation; without changing the capacitor bank, merely by changing the electrode configuration and the operating pressure. The Lee model code was also used to run numerical experiments on plasma focus devices for optimizing soft x-ray yield with reducing L o , varying L o and 'a' to get engineering designs with maximum soft x-ray yield for these devices at different experimental conditions and gases. Numerical experiments showed the influence of the gas used in plasma focus and its properties on soft x-ray emission and its properties and then on its applications. Scaling laws for soft x-ray of nitrogen, oxygen, neon, argon, krypton and xenon plasma focus, in terms of energy, peak discharge current and focus pinch current were found. Radiative cooling effects are studied indicating that radiative collapse may be observed for heavy noble gases (Ar, Kr, Xe) for pinch currents even below 100 kA. The results show that the line radiation emission and tube voltages have

  1. Translating a Narrative of Migration: reflections and strategies towards countering xenophobic discourse in the Italian version of Russell Banks' Continental Drift

    Directory of Open Access Journals (Sweden)

    Paola Brusasco

    2014-12-01

    Full Text Available Collective identities and power relations are the result of converging projections deriving from history, geography, language, religion, memories and customs that – informed by more or less acknowledged ideologies – contribute to shaping them. Translation too, as a language interface, plays a relevant role in both representing Self and the Other and confirming or challenging power relations through various operations that include discourse shifts and a questioning of accepted meanings and practices. This paper revolves around the main strategies adopted in the translation of Russell Bank's novel Continental Drift into Italian at a time (2009-10 when political discourse in the target culture mainly constructed immigrants asan undifferentiated category threatening citizens' jobs, health and safety. Although written in 1985 and set in America around that time, the novel focuses on economic crises and tragedies of migration which evoke images of contemporary Italy and require a highly connoted lexicon. In the context of fear and social conflict promoted in Italy by the then political forces in power to justify restrictive laws, the translator envisaged herself as an “agent of social change” (Tymoczko 2003 who did not want to be complicit with such discourse. Therefore, in translating the novel, a kind of “pre-emptive critical discourse analysis” was adopted, whereby lexical items, syntactic structures and the resulting pragmatic contexts were weighed in the light of how the target text would inscribe itself in the receiving culture so as to avoid – as far as possible – resonances and associations that might support prejudice. Some of the translator's considerations and solutions will be discussed as attempts (however ideologically connoted too to avoid an a-critical use of language and find a balance between ethical issues and the “naturalness” usually required by the publishing sector.

  2. Effects of autism spectrum disorders on outcome in teenage-onset anorexia nervosa evaluated by the Morgan-Russell outcome assessment schedule: a controlled community-based study.

    Science.gov (United States)

    Nielsen, Søren; Anckarsäter, Henrik; Gillberg, Carina; Gillberg, Christopher; Råstam, Maria; Wentz, Elisabet

    2015-01-01

    The purpose of the study was to evaluate time trends and effects of co-existing autism spectrum disorders (ASD) on outcome in an ongoing long-term follow-up study of anorexia nervosa (AN). The Morgan-Russell Outcome Assessment Schedule (MROAS) was used at 6-, 10- and 18-year follow-up of a representative sample of 51 individuals with teenage-onset AN and a matched group of 51 healthy comparison cases. The full multinomial distribution of responses for the full scale and each of the subscales was evaluated using exact nonparametric statistical methods. The impact of diagnostic stability of ASD on outcome in AN was evaluated in a dose-response model. There were no deaths in either group. Food intake and menstrual pattern were initially poor in the AN group but normalised over time. MROAS 'mental state' was much poorer in the AN group and did not improve over time. The psychosexual MROAS domains 'attitudes' and 'aims' showed persistent problems in the AN group. In the MROAS socioeconomic domain, the subscales 'personal contacts', 'social activities' and 'employment record' all showed highly significant between-group differences at all three follow-ups. A statistically significant negative dose-response relationship was found between a stable diagnosis of ASD over time and the results on the subscales 'mental state', 'psychosexual state' and 'socio-economic state'. Outcome of teenage-onset AN is favourable with respect to mortality and persisting eating disorder, but serious problems remain in the domains 'mental state', 'psychosexual function' and 'socioeconomic state'. Outcome is considerably worse if ASD is present. Treatment programmes for AN need to be modified so as to accommodate co-existing ASD.

  3. CAN WE PREDICT THE GLOBAL MAGNETIC TOPOLOGY OF A PRE-MAIN-SEQUENCE STAR FROM ITS POSITION IN THE HERTZSPRUNG–RUSSELL DIAGRAM?

    International Nuclear Information System (INIS)

    Gregory, S. G.; Hillenbrand, L. A.; Donati, J.-F.; Morin, J.; Hussain, G. A. J.; Mayne, N. J.; Jardine, M.

    2012-01-01

    Zeeman-Doppler imaging studies have shown that the magnetic fields of T Tauri stars can be significantly more complex than a simple dipole and can vary markedly between sources. We collect and summarize the magnetic field topology information obtained to date and present Hertzsprung-Russell (H-R) diagrams for the stars in the sample. Intriguingly, the large-scale field topology of a given pre-main-sequence (PMS) star is strongly dependent upon the stellar internal structure, with the strength of the dipole component of its multipolar magnetic field decaying rapidly with the development of a radiative core. Using the observational data as a basis, we argue that the general characteristics of the global magnetic field of a PMS star can be determined from its position in the H-R diagram. Moving from hotter and more luminous to cooler and less luminous stars across the PMS of the H-R diagram, we present evidence for four distinct magnetic topology regimes. Stars with large radiative cores, empirically estimated to be those with a core mass in excess of ∼40% of the stellar mass, host highly complex and dominantly non-axisymmetric magnetic fields, while those with smaller radiative cores host axisymmetric fields with field modes of higher order than the dipole dominant (typically, but not always, the octupole). Fully convective stars above ∼> 0.5 M ☉ appear to host dominantly axisymmetric fields with strong (kilo-Gauss) dipole components. Based on similarities between the magnetic properties of PMS stars and main-sequence M-dwarfs with similar internal structures, we speculate that a bistable dynamo process operates for lower mass stars (∼ ☉ at an age of a few Myr) and that they will be found to host a variety of magnetic field topologies. If the magnetic topology trends across the H-R diagram are confirmed, they may provide a new method of constraining PMS stellar evolution models.

  4. IGF2/H19 hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome

    Directory of Open Access Journals (Sweden)

    Kannenberg Kai

    2012-09-01

    Full Text Available Abstract Background Silver-Russell syndrome (SRS is characterized by severe intrauterine and postnatal growth failure and frequent body asymmetry. Half of the patients with SRS carry a DNA hypomethylation of the imprinting center region 1 (ICR1 of the insulin-like growth factor 2 (IGF2/H19 locus, and the clinical phenotype is most severe in these patients. We aimed to elucidate the epigenetic basis of asymmetry in SRS and the cellular consequences of the ICR1 hypomethylation. Results The ICR1 methylation status was analyzed in blood and in addition in buccal smear probes and cultured fibroblasts obtained from punch biopsies taken from the two body halves of 5 SRS patients and 3 controls. We found that the ICR1 hypomethylation in SRS patients was stronger in blood leukocytes and oral mucosa cells than in fibroblasts. ICR1 CpG sites were affected differently. The severity of hypomethylation was not correlated to body asymmetry. IGF2 expression and IGF-II secretion of fibroblasts were not correlated to the degree of ICR1 hypomethylation. SRS fibroblasts responded well to stimulation by recombinant human IGF-I or IGF-II, with proliferation rates comparable with controls. Clonal expansion of primary fibroblasts confirmed the complexity of the cellular mosaicism. Conclusions We conclude that the ICR1 hypomethylation SRS is tissue, cell, and CpG site specific. The correlation of the ICR1 hypomethylation to IGF2 and H19 expression is not strict, may depend on the investigated tissue, and may become evident only in case of more severe methylation defects. The body asymmetry in juvenile SRS patients is not related to a corresponding ICR1 hypomethylation gradient, rendering more likely an intrauterine origin of asymmetry. Overall, it may be instrumental to consider not only the ICR1 methylation status as decisive for IGF2/H19 expression regulation.

  5. Inhibition of secretary PLA₂--VRV-PL-VIIIa of Russell's viper venom by standard aqueous stem bark extract of Mangifera indica L.

    Science.gov (United States)

    Dhananjaya, B L; Sudarshan, S

    2015-03-01

    The aqueous extract of Mangifera indica is known to possess anti-snake venom activities. However, its inhibitory potency and mechanism of action on multi-toxic phospholipases A2s, which are the most toxic and lethal component of snake venom is still unknown. Therefore, this study was carried out to evaluate the modulatory effect of standard aqueous bark extract of M. indica on VRV-PL-VIIIa of Indian Russells viper venom. Mangifera indica extract dose dependently inhibited the GIIB sPLA2 (VRV-PL-VIIIa) activity with an IC50 value of 6.8±0.3 μg/ml. M. indica extract effectively inhibited the indirect hemolytic activity up to 96% at ~40 μg/ml concentration. Further, M. indica extract at different concentrations (0-50 μg/ml) inhibited the edema formed in a dose dependent manner. It was found that there was no relieve of inhibitory effect of the extract when examined as a function of increased substrate and calcium concentration. The inhibition was irreversible as evident from binding studies. The in vitro inhibition is well correlated with in situ and in vivo edema inducing activities. As the inhibition is independent of substrate, calcium concentration and was irreversible, it can be concluded that M. indica extracts mode of inhibition could be due to direct interaction of components present in the extract with PLA2 enzyme. In conclusion, the aqueous extract of M. indica effectively inhibits svPLA2 (Snake venom phospholipase A2) enzymatic and its associated toxic activities, which substantiate its anti-snake venom properties. Further in-depth studies are interesting to known on the role and mechanism of the principal inhibitory constituents present in the extract, so as to develop them into potent anti-snake venom and as an anti-inflammatory agent.

  6. Yield stability in maize (Zea mays L. and correlations among the parameters of the Eberhart and Russell, Lin and Binns and Huehn models

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Scapim

    2000-06-01

    Full Text Available Assessment of the stability and adaptability of a genotype to different environments is useful for recommending cultivars for known conditions of cultivation and should be a requirement in breeding programs. Twenty maize (Zea mays L. cultivars were tested at eight locations in Minas Gerais by the National Center for Maize and Sorghum Research (CNPMS of the Brazilian Enterprise for Agricultural Research (EMBRAPA for two years. The experiments involved a randomized complete block design in which three procedures were used to analyze cultivar stability and adaptability. The level of association among the parameters obtained by the three methods was assessed using Spearman's rank correlation. Hybrids 'DINA 170', 'G-96C', 'C 505', 'DINA 70' and 'C 435' had a mean yield greater than 6,000 kg/ha. Eberhart and Russell's regression coefficient (betai was negative and correlated significantly (P or = 0.05, but correlated positively with Si(1 (P O conhecimento sobre a estabilidade e adaptabilidade de comportamento de genótipos contém informações muito úteis para a recomendação de cultivares para condições de cultivo conhecidas a priori, de modo que a avaliação da resposta dos genótipos às variações ambientais deve ser etapa obrigatória em programas de melhoramento. Para caracterizar 20 cultivares de milho, foram realizados dez ensaios (oito localidades do Estado de Minas Gerais, em dois anos no delineamento de blocos ao acaso, pelo Centro Nacional de Pesquisa de Milho e Sorgo (CNPMS da Empresa Brasileira de Pesquisa Agropecuária (Embrapa. Três procedimentos estatísticos foram adotados para a análise da estabilidade e adaptabilidade dos cultivares e avaliou-se o grau de associação entre os parâmetros dos três métodos por meio da correlação classificatória de Spearman. 'DINA 170', 'G-96C', 'C 505', 'DINA 70' e 'C 435' destacaram-se com produtividades médias superiores a 6.000 kg/ha. O coeficiente de regressão (betai de Eberhart

  7. Level II scour analysis for Bridge 63 (MTH0TH00120063) on Town Highway 12, crossing Russell Brook, Mount Holly, Vermont

    Science.gov (United States)

    Wild, Emily C.; Severance, Timothy

    1998-01-01

    This report provides the results of a detailed Level II analysis of scour potential at structure MTHOTH00120063 on Town Highway 12 crossing Russell Brook, Mount Holly, Vermont (figures 1–8). A Level II study is a basic engineering analysis of the site, including a quantitative analysis of stream stability and scour (FHWA, 1993). Results of a Level I scour investigation also are included in appendix E of this report. A Level I investigation provides a qualitative geomorphic characterization of the study site. Information on the bridge, gleaned from Vermont Agency of Transportation (VTAOT) files, was compiled prior to conducting Level I and Level II analyses and is found in appendix D. The site is in the Green Mountain section of the New England physiographic province in south-central Vermont. The 3.6-mi2 drainage area is in a predominantly rural and forested basin. In the vicinity of the study site, the surface cover is forest upstream and downstream of the bridge. In the study area, Russell Brook has an incised, sinuous channel with a slope of approximately 0.0263 ft/ft, an average channel top width of 29 ft and an average bank height of 3 ft. The channel bed material ranges from cobbles to boulders with a median grain size (D50) of 97.1 mm (0.318 ft). The geomorphic assessment at the time of the Level I and Level II site visit on October 4, 1995, indicated that the reach was stable. The Town Highway 12 crossing of Russell Brook is a 29-ft-long, one-lane bridge consisting of a 26-foot steel-stringer span (Vermont Agency of Transportation, written communication, March 21, 1995). The opening length of the structure parallel to the bridge face is 23.5 ft. The bridge is supported by vertical, concrete abutments with wingwalls. The channel is skewed approximately 40 degrees to the opening while the computed opening-skew-to-roadway is 35 degrees. During the Level I assessment, it was observed that the upstream left wingwall footing was exposed 0.2 ft, in reference to

  8. Dreams of the Hmong Kingdom: The Quest for Legitimation in French Indochina, 1850- 1960, by Mai Na M. Lee. Madison, University of Wisconsin Press, 2015. 430 pages.

    Directory of Open Access Journals (Sweden)

    Nengher N. Vang

    2015-12-01

    Full Text Available This article provides a book review of Mai Na M. Lee’s Dreams of the Hmong Kingdom: The Quest for Legitimation in French Indochina, 1850-1960. Dreams of the Hmong Kingdom. It highlights the contribution of the book to the historiography of the Hmong and provides a critical assessment of the dichotomous analytical framework that Lee uses to analyze the rivalry between Hmong messianic leaders and Hmong political brokers and the competition between the Ly and Lo clans for paramountcy in French Indochina

  9. Lauren Berlant and Lee Edelman, Sex, Or The Unbearable (Durham: Duke University Press, 2014, pp. 168, ISBN: 9780822355946, £13.99, paperback.

    Directory of Open Access Journals (Sweden)

    Hannah Proctor

    2014-01-01

    Full Text Available 'So few colleges and universities bother to teach human sexuality...so much stigma adheres even to scholarly investigation of sex,' Gayle Rubin lamented in her 1984 essay 'Thinking Sex'. But it was an academic conference on Rubin's work - 'Rethinking Sex', a lavish threeday event, held at the University of Pennsylvania in 2009 - that provided the initial impetus for Lauren Berlant and Lee Edelman to enter into a dialogue on sexuality. The result is Sex, or the Unbearable, published by Duke University Press, the first in a series on queer theory edited by the authors.

  10. Topography and vegetation as predictors of snow water equivalent across the alpine treeline ecotone at Lee Ridge, Glacier National Park, Montana, U.S.A.

    Science.gov (United States)

    Geddes, C.A.; Brown, D.G.; Fagre, D.B.

    2005-01-01

    We derived and implemented two spatial models of May snow water equivalent (SWE) at Lee Ridge in Glacier National Park, Montana. We used the models to test the hypothesis that vegetation structure is a control on snow redistribution at the alpine treeline ecotone (ATE). The statistical models were derived using stepwise and "best" subsets regression techniques. The first model was derived from field measurements of SWE, topography, and vegetation taken at 27 sample points. The second model was derived using GIS-based measures of topography and vegetation. Both the field- (R² = 0.93) and GIS-based models (R² = 0.69) of May SWE included the following variables: site type (based on vegetation), elevation, maximum slope, and general slope aspect. Site type was identified as the most important predictor of SWE in both models, accounting for 74.0% and 29.5% of the variation, respectively. The GIS-based model was applied to create a predictive map of SWE across Lee Ridge, predicting little snow accumulation on the top of the ridge where vegetation is scarce. The GIS model failed in large depressions, including ephemeral stream channels. The models supported the hypothesis that upright vegetation has a positive effect on accumulation of SWE above and beyond the effects of topography. Vegetation, therefore, creates a positive feedback in which it modifies its, environment and could affect the ability of additional vegetation to become established.

  11. Samuel Holden Parsons Lee (1772-1863): American physician, entrepreneur and selfless fighter of the 1798 Yellow Fever epidemic of New London, Connecticut.

    Science.gov (United States)

    Mattie, James K; Desai, Sukumar P

    2015-02-01

    Samuel Holden Parsons Lee practised medicine at a time when the germ theory of disease had not yet been proposed and antibiotics remained undiscovered. In 1798 he served selflessly as the only physician in town who was willing to battle the Yellow Fever outbreak of New London, Connecticut. Because he practised at the dawn of the age of patent medicine, unfortunately his name also came to be associated with medical quackery. We argue that his contributions have been grossly underestimated. He compounded and vended medications - including bilious pills and bitters - that were gold standards of the day. Moreover, one preparation for treatment of kidney stones led to his sub-specialization in this field and was met with such success that its sale continued for nearly 100 years after his death. While a talented medical man, Lee also had a knack for business, finding success in trading, whaling and real estate. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  12. Walter Russell's concepts as the basis for an alternative view on radioactivity induced oxygen-ozone depletion and food chain pollution; and as the basis for alternative fuels, materials, energy production, and radioactive waste cleanup

    International Nuclear Information System (INIS)

    Binder, T.A.

    1993-01-01

    The following topics with supporting data will be presented: The transmutation of atmospheric nitrogen into carbon 14 and tritium via radioactivity as a source of omnipresent food and water pollution, and the possible correlation of oxygen transmutation into carbon 14 and tritium by the same mechanisms as well as into sulfur. Walter Russell's four pole field dual polarity control as a basis for transmutation will be discussed with reference to past and contemporary results of experimentation on this basis. Extension of the concepts into free hydrogen energy fuel, nitrogen fertilizers, other materials production,and transmutation of radioactive wastes into non radioactive elements will be discussed

  13. 7th February 2011 - Scottish Cabinet Secretary for Education and Lifelong Learning M. Russell MSP signing the guest book with Beams Department Head P. Collier and Adviser J. Ellis

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    01-17:Scottish Cabinet Secretary for Education and Lifelong Learning M. Russell MSP signing the guest book with Beams Department Head P. Collier and Adviser J. Ellis 18-22: Teachers and Pupils signing the guest book 23-27: visiting the CERN control centre with P. Collier 28-32: visiting the LHCb underground area 33-74: visitng the ATLAS underground area Other members of the delegation: Chief Scientific Adviser to the Scottish Government and Chair in Molecular and Cell Biology at the University of Aberdeen A. Glover; Assistant Private Secretary M. Gallagher; Associate Director Institute for Gravitational Research, University of Glasgow J.Hough.

  14. A multi-method approach to the molecular diagnosis of overt and borderline 11p15.5 defects underlying Silver-Russell and Beckwith-Wiedemann syndromes.

    Science.gov (United States)

    Russo, Silvia; Calzari, Luciano; Mussa, Alessandro; Mainini, Ester; Cassina, Matteo; Di Candia, Stefania; Clementi, Maurizio; Guzzetti, Sara; Tabano, Silvia; Miozzo, Monica; Sirchia, Silvia; Finelli, Palma; Prontera, Paolo; Maitz, Silvia; Sorge, Giovanni; Calcagno, Annalisa; Maghnie, Mohamad; Divizia, Maria Teresa; Melis, Daniela; Manfredini, Emanuela; Ferrero, Giovanni Battista; Pecile, Vanna; Larizza, Lidia

    2016-01-01

    Multiple (epi)genetic defects affecting the expression of the imprinted genes within the 11p15.5 chromosomal region underlie Silver-Russell (SRS) and Beckwith-Wiedemann (BWS) syndromes. The molecular diagnosis of these opposite growth disorders requires a multi-approach flowchart to disclose known primary and secondary (epi)genetic alterations; however, up to 20 and 30 % of clinically diagnosed BWS and SRS cases remain without molecular diagnosis. The complex structure of the 11p15 region with variable CpG methylation and low-rate mosaicism may account for missed diagnoses. Here, we demonstrate the relevance of complementary techniques for the assessment of different CpGs and the importance of testing multiple tissues to increase the SRS and BWS detection rate. Molecular testing of 147 and 450 clinically diagnosed SRS and BWS cases provided diagnosis in 34 SRS and 185 BWS patients, with 9 SRS and 21 BWS cases remaining undiagnosed and herein referred to as "borderline." A flowchart including complementary techniques and, when applicable, the analysis of buccal swabs, allowed confirmation of the molecular diagnosis in all borderline cases. Comparison of methylation levels by methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) in borderline and control cases defined an interval of H19/IGF2:IG-DMR loss of methylation that was distinct between "easy to diagnose" and "borderline" cases, which were characterized by values ≤mean -3 standard deviations (SDs) compared to controls. Values ≥mean +1 SD at H19/IGF2: IG-DMR were assigned to borderline hypermethylated BWS cases and those ≤mean -2 SD at KCNQ1OT1: TSS-DMR to hypomethylated BWS cases; these were supported by quantitative pyrosequencing or Southern blot analysis. Six BWS cases suspected to carry mosaic paternal uniparental disomy of chromosome 11 were confirmed by SNP array, which detected mosaicism till 10 %. Regarding the clinical presentation, borderline SRS were representative

  15. HYDRAULICS, Russell COUNTY, KENTUCKY, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  16. Alfred Russel Wallace deserves better

    Indian Academy of Sciences (India)

    2010-06-30

    Jun 30, 2010 ... Like Darwin, he was a truly remarkable nineteenth century intellect and polymath and, according to a recent book by Roy Davies (The Darwin conspiracy: origins of a scientific crime), he has a stronger claim to the Theory of Evolution by Natural Selection than has Darwin. Here we present a critical ...

  17. Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM pilot): study protocol for a randomized controlled trial.

    Science.gov (United States)

    Sackley, Catherine M; Smith, Christina H; Rick, Caroline; Brady, Marian C; Ives, Natalie; Patel, Ramilla; Roberts, Helen; Dowling, Francis; Jowett, Sue; Wheatley, Keith; Patel, Smitaa; Kelly, Debbie; Sands, Gina; Clarke, Carl

    2014-06-07

    Parkinson's disease is a common movement disorder affecting approximately 127,000 people in the UK, with an estimated two thirds having speech-related problems. Currently there is no preferred approach to speech and language therapy within the NHS and there is little evidence for the effectiveness of standard NHS therapy or Lee Silverman voice treatment. This trial aims to investigate the feasibility and acceptability of randomizing people with Parkinson's disease-related speech or voice problems to Lee Silverman voice treatment or standard speech and language therapy compared to a no-intervention control. The PD COMM pilot is a three arm, assessor-blinded, randomized controlled trial. Randomization will be computer-generated with participants randomized at a ratio of 1:1:1. Participants randomized to intervention arms will be immediately referred to the appropriate speech and language therapist. The target population are patients with a confirmed diagnosis of idiopathic Parkinson's disease who have problems with their speech or voice. The Lee Silverman voice treatment intervention group will receive the standard regime of 16 sessions between 50 and 60 minutes in length over four weeks, with extra home practice. The standard speech and language therapy intervention group will receive a dose determined by patients' individual needs, but not exceeding eight weeks of treatment. The control group will receive standard care with no speech and language therapy input for at least six months post-randomization. Outcomes will be assessed at baseline (pre-randomization) and post- randomization at three, six, and 12 months. The outcome measures include patient-reported voice measures, quality of life, resource use, and assessor-rated speech recordings. The recruitment aim is at least 60 participants over 21 months from 11 sites, equating to at least 20 participants in each arm of the trial. This trial is ongoing and recruitment commenced in May 2012. This study will

  18. Reorientando a identidade nacional em Native speaker, de Chang-rae Lee, e O sol se põe em São Paulo, de Bernardo Carvalho

    Directory of Open Access Journals (Sweden)

    Rex P. Nielson

    2014-01-01

    Full Text Available A comparative reading of the novels Native speaker (1995, by the North American writer Chang-rae Lee, and O sol se põe em São Paulo (2007, by Bernardo Carvalho, allows for a reevaluation of how minority identities have been constructed in the two American megalopolises New York and São Paulo. The plotlines of both nove ls hinge on the identity crisis of a second-generation Asian immigrant (from Korea in one case and Japan in the other who is seeking to negotiate his American identity (speaking in hemispheric terms in terms of his family‟s origin and language. However, despite the similar anxieties over assimilation present in both novels, they both reveal significant differences regarding the ways in which the United States and Brazil have responded to cultural difference even as they challenge national myths of inclusi on and belonging.

  19. Samsung : Lee Byung Chull, créateur d’un modèle mondial (1938-1987)

    OpenAIRE

    Park-Barjot, Rang-Ri

    2012-01-01

    Samsung, la firme aux « trois étoiles », a été fondée en 1938 par Lee Byung Chull, un entrepreneur d’exception. D’abord connu pour ses produits bas de gamme et bon marché, le groupe s’est imposé à la pointe de la technologie grâce à un modèle industriel efficace. En dépit de sa diversification, Samsung est devenu l’un des leaders mondiaux de l’ère numérique. Samsung a réalisé une spectaculaire percée dans l’électrotechnique et l’électronique, à travers sa filiale Samsung Electronics, leader m...

  20. Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-κB activation.

    Science.gov (United States)

    Royan, Sandhya V; Jones, Rheinallt M; Koutsouris, Athanasia; Roxas, Jennifer L; Falzari, Kanakeshwari; Weflen, Andrew W; Kim, Amy; Bellmeyer, Amy; Turner, Jerrold R; Neish, Andrew S; Rhee, Ki-Jong; Viswanathan, V K; Hecht, Gail A

    2010-12-01

    Enteric bacterial pathogens have evolved sophisticated strategies to evade host immune defences. Some pathogens deliver anti-inflammatory effector molecules into the host cell cytoplasm via a type III secretion system (T3SS). Enteropathogenic Escherichia coli (EPEC) inhibits inflammation by an undefined, T3SS-dependent mechanism. Two proteins encoded outside of the EPEC locus of enterocyte effacement (LEE) pathogenicity island, non-LEE-encoded effector H1 (NleH1) and H2 (NleH2), display sequence similarity to Shigella flexneri OspG, which inhibits activation of the pro-inflammatory transcription factor NF-κB. We hypothesized that the anti-inflammatory effects of EPEC were mediated by NleH1 and NleH2. In this study, we examined the effect of NleH1/H2 on the NF-κB pathway. We show that NleH1/H2 are secreted via the T3SS and that transfection of cells with plasmids harbouring nleH1 or nleH2 decreased IKK-β-induced NF-κB activity and attenuated TNF-α-induced degradation of phospho-IκBα by preventing ubiquitination. Serum KC levels were higher in mice infected with ΔnleH1H2 than those infected with WT EPEC, indicating that NleH1/H2 dampen pro-inflammatory cytokine expression. ΔnleH1H2 was cleared more rapidly than WT EPEC while complementation of ΔnleH1H2 with either NleH1 or NleH2 prolonged colonization. Together, these data show that NleH1 and NleH2 function to dampen host inflammation and facilitate EPEC colonization during pathogenesis. © 2010 Blackwell Publishing Ltd.

  1. Practical aspects of Lee Goldburg based CRAMPS techniques for high-resolution 1H NMR spectroscopy in solids: Implementation and applications

    Science.gov (United States)

    Coelho, Cristina; Rocha, João; Madhu, P. K.; Mafra, Luís

    2008-10-01

    Elucidating the local environment of the hydrogen atoms is an important problem in materials science. Because 1H spectra in solid-state nuclear magnetic resonance (NMR) suffer from low resolution due to homogeneous broadening, even under magic-angle spinning (MAS), information of chemical interest may only be obtained using certain high-resolution 1H MAS techniques. 1H Lee-Goldburg (LG) CRAMPS (Combined Rotation And Multiple-Pulse Spectroscopy) methods are particularly well suited for studying inorganic-organic hybrid materials, rich in 1H nuclei. However, setting up CRAMPS experiments is time-consuming and not entirely trivial, facts that have discouraged their widespread use by materials scientists. To change this status quo, here we describe and discuss some important aspects of the experimental implementation of CRAMPS techniques based on LG decoupling schemes, such as FSLG (Frequency Switched), and windowed and windowless PMLG (Phase Modulated). In particular, we discuss the influence on the quality of the 1H NMR spectra of the different parameters at play, for example LG (Lee-Goldburg) pulses, radio-frequency ( rf) phase, frequency switching, and pulse imperfections, using glycine and adamantane as model compounds. The efficiency and robustness of the different LG-decoupling schemes is then illustrated on the following materials: organo-phosphorus ligand, N-(phosphonomethyl)iminodiacetic acid [H 4pmida] [I], and inorganic-organic hybrid materials (C 4H 12N 2)[Ge 2(pmida) 2OH 2]·4H 2O [II] and (C 2H 5NH 3)[Ti(H 1.5PO 4)(PO 4)] 2·H 2O [III].

  2. Mesophilic and thermophilic anaerobic co-digestion of winery wastewater sludge and wine lees: An integrated approach for sustainable wine production.

    Science.gov (United States)

    Da Ros, C; Cavinato, C; Pavan, P; Bolzonella, D

    2017-12-01

    In this work, winery wastes generated by a cellar producing approximately 300,000 hL of wine per year was monitored for a period of one year. On average, 196 L of wastewater, 0.1 kg of waste activated sludge (dry matter) and 1.6 kg of wine lees were produced per hectoliter of wine produced. Different winery wastes, deriving from different production steps, namely waste activated sludge from wastewater treatment and wine lees, were co-treated using an anaerobic digestion process. Testing was conducted on a pilot scale for both mesophilic and thermophilic conditions. The process was stable for a long period at 37 °C, with an average biogas production of 0.386 m 3 /kg COD fed . On the other hand, for thermophilic conditions, volatile fatty acids accumulated in the reactor and the process failed after one hydraulic retention time (23 days). In order to fix the biological process, trace elements (iron, cobalt and nickel) were added to the feed of the thermophilic reactor. Metals augmentation improved process stability and yields at 55 °C. The pH ranged between 7.8 and 8.0, and specific gas production was 0.450 m 3 /kg COD fed , which corresponded to dry matter and COD removals of 34% and 88%, respectively. Although the observed performances in terms of biogas production were good, the thermophilic process exhibited some limitations related to both the necessity of metals addition and the worse dewaterability properties. In fact, while the mesophilic digestates reached a good dewatering quality via the addition of 6.5 g of polymer per kg of dry matter, the required dosage for the thermophilic sludge was greater than 10 g/kg of dry matter. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Tratamento dos distúrbios da voz na doença de Parkinson: o método Lee Silverman

    Directory of Open Access Journals (Sweden)

    Dias Alice Estevo

    2003-01-01

    Full Text Available Alterações discretas na qualidade da voz e da articulação podem ser observadas em fases relativamente iniciais da doença de Parkinson (DP. As alterações da voz e da fala na DP constituem, em conjunto, o que se denomina disartria hipocinética ou disartrofonia e caracterizam-se por monotonia e redução da intensidade da voz, articulação imprecisa e distúrbios do ritmo. Recentemente, foram relatados resultados favoráveis através de método de tratamento intensivo e dirigido especificamente para o tratamento da voz na DP, denominado Lee Silverman Voice Treatment (LSVT®. O objetivo essencial desse método é aumentar a intensidade vocal através do incremento do esforço fonatório. O presente estudo teve por objetivo a caracterização das anormalidades vocais (qualidade vocal, padrão articulatório e inteligibilidade em um grupo de pacientes com DP e a avaliação da resposta terapêutica obtida pela administração do método Lee Silverman. A comparação dos dados de análise acústica, bem como da análise perceptivo-auditiva nos períodos pré e pós-tratamento mostraram modificações estatisticamente significantes após o tratamento. Embora o padrão articulatório tenha se mantido impreciso, os benefícios obtidos pelo tratamento na melhora da qualidade vocal e, sobretudo, na intensidade vocal favoreceram a qualidade da comunicação oral, reduziram os sintomas negativos e adequaram a qualidade vocal às necessidades pessoais e sociais dos indivíduos.

  4. The effects of Hurricane Irene and Tropical Storm Lee on the bed sediment geochemistry of U.S. Atlantic coastal rivers

    Science.gov (United States)

    Horowitz, Arthur J.

    2013-01-01

    Hurricane Irene and Tropical Storm Lee, both of which made landfall in the U.S. between late August and early September 2011, generated record or near record water discharges in 41 coastal rivers between the North Carolina/South Carolina border and the U.S./Canadian border. Despite the discharge of substantial amounts of suspended sediment from many of these rivers, as well as the probable influx of substantial amounts of eroded material from the surrounding basins, the geochemical effects on the wastewater/solid sludge. The limited number of significant sediment-associated chemical changes that were detected probably resulted from two potential processes: (1) the flushing of in-stream land-use affected sediments that were replaced by baseline material more representative of local geology and/or soils (declining concentrations), and/or (2) the inclusion of more heavily affected material as a result of urban nonpoint-source runoff and/or releases from flooded treatment facilities (increasing concentrations). Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

  5. Social networks and inference about unknown events: A case of the match between Google’s AlphaGo and Sedol Lee

    Science.gov (United States)

    Bae, Jonghoon; Cha, Young-Jae; Lee, Hyungsuk; Lee, Boyun; Baek, Sojung; Choi, Semin

    2017-01-01

    This study examines whether the way that a person makes inferences about unknown events is associated with his or her social relations, more precisely, those characterized by ego network density that reflects the structure of a person’s immediate social relation. From the analysis of individual predictions over the Go match between AlphaGo and Sedol Lee in March 2016 in Seoul, Korea, this study shows that the low-density group scored higher than the high-density group in the accuracy of the prediction over a future state of a social event, i.e., the outcome of the first game. We corroborated this finding with three replication tests that asked the participants to predict the following: film awards, President Park’s impeachment in Korea, and the counterfactual assessment of the US presidential election. Taken together, this study suggests that network density is negatively associated with vision advantage, i.e., the ability to discover and forecast an unknown aspect of a social event. PMID:28222114

  6. Time-lapse analysis of methane quantity in Mary Lee group of coal seams using filter-based multiple-point geostatistical simulation

    Science.gov (United States)

    Karacan, C. Özgen; Olea, Ricardo A.

    2013-01-01

    Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area.

  7. Crescimento de Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae sob diferentes níveis de sombreamento Growth of Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong (Leguminosae under different shading levels

    Directory of Open Access Journals (Sweden)

    Ana Lúcia da Silva Lima

    2010-03-01

    Full Text Available Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. é uma espécie clímax tolerante a sombra, ao passo que Enterolobium contortisiliquum (Vell. Morong. é uma espécie pioneira. O desenvolvimento destas espécies pode refletir a habilidade de adaptação aos diferentes fatores ambientais (luz, água e temperatura no local em que estão crescendo. O suprimento inadequado de um desses fatores pode reduzir o vigor da planta e limitar seu desenvolvimento. O presente trabalho teve como objetivo avaliar os efeitos do nível de sombreamento no crescimento e a concentração de pigmentos fotossintéticos em duas espécies de leguminosas arbóreas, Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. e Enterolobium contortisiliquum (Vell. Morong. O experimento foi conduzido no Setor de Olericultura do Centro Universitário Luterano de Ji-Paraná (CEULJI/ULBRA/Rondônia. Durante a formação das mudas, ambas as espécies foram expostas a quatro tratamentos de sombra: 0 % (controle - sol pleno; 30 %; 50 % e 80 %. Cada tratamento foi constituído com três repetições de cada espécie; o delineamento experimental foi inteiramente casualisado. Quatro meses após a semeadura, as seguintes análises foram realizadas: número de folhas, altura da planta, comprimento do sistema radicular, massa seca total e concentração de pigmentos fotossintéticos. O tratamento sob sol pleno afetou negativamente o crescimento de ambas as espécies. As mudas crescidas sob 50% e 80% apresentaram melhor desenvolvimento. Conforme o aumento do sombreamento houve um decréscimo na razão clorofila a/b e um aumento nas concentrações de clorofila total e carotenóides totais.Hymenaea courbaril L. var. stilbocarpa (Hayne Lee et Lang. is a clímax shadow tolerant specie and Enterolobium contortisiliquum (Vell. Morong., by the other hand, is considered as a pioneer specie. The development of these species may reflect its adaptation ability to different environmental

  8. The effectiveness of Lee Silverman Voice Treatment therapy issued interactively through an iPad device: A non-inferiority study.

    Science.gov (United States)

    Griffin, Murray; Bentley, John; Shanks, Joseph; Wood, Carly

    2018-04-01

    Introduction This study compared the differences in recorded speech variables between people treated with conventional 'in person' Lee Silverman Voice Treatment (LSVT) and those treated remotely via iPad-based 'Facetime'. Method Eight participants were selected for the iPad LSVT, and 21 similarly matched subjects were selected from existing data to form the 'in person' group. Participants in both groups had diagnosed idiopathic Parkinson's disease and moderate hypokinetic dysarthria. Eighteen sessions of prescribed LSVT comprising a pre-treatment assessment, 16 treatment sessions, and a six months' post-treatment assessment were administered for each person. In both groups, pre- and post-treatment assessments were conducted face-to-face. Performance measures were recorded during assessment and treatment. Average measures were determined for all tasks at all time points and a summary outcome variable was composed from across-task performance. Results Non-inferiority testing confirmed that iPad LSVT was non-inferior in treating all LSVT task 3 variables except generating words, with the 90% upper confidence intervals (CI) lying between the non-inferiority margin of ± 2.25 and zero. The iPad was superior in treating the task 3 rainbow reading passage and describing motor task variables with upper and lower 90% CI values being negative. The improvement in the summary outcome variable score was also superior in the iPad group. Discussion Non-inferiority testing implies that the iPad LSVT is non-inferior in treating task three variables when compared to traditional LSVT. The study supports further development of remote delivery solutions involving the Apple iPad and 'Facetime' system as a means of improving access to services and the participant's experience.

  9. Use of Antibody Responses against Locus of Enterocyte Effacement (LEE)-Encoded Antigens To Monitor Enterohemorrhagic Escherichia coli Infections on Cattle Farms

    Science.gov (United States)

    Joris, Maria-Adelheid; Vanrompay, Daisy; Verstraete, Karen; De Reu, Koen; De Zutter, Lieven

    2013-01-01

    Enterohemorrhagic Escherichia coli (EHEC) is a significant zoonotic pathogen causing severe disease associated with watery and bloody diarrhea, hemorrhagic colitis, and the hemolytic-uremic syndrome (HUS) in humans. Infections are frequently associated with contact with EHEC-contaminated ruminant feces. Both natural and experimental infection of cattle induces serum antibodies against the LEE-encoded proteins intimin, EspA, EspB, and Tir and the Shiga toxins Stx1 and Stx2, although the latter are poorly immunogenic in cattle. We determined whether antibodies and/or the kinetics of antibody responses against intimin, Tir, EspA, and/or EspB can be used for monitoring EHEC infections in beef cattle herds in order to reduce carcass contamination at slaughter. We examined the presence of serum antibodies against recombinant O157:H7 E. coli intimin EspA, EspB, and Tir during a cross-sectional study on 12 cattle farms and during a longitudinal time course study on two EHEC-positive cattle farms. We searched for a possible correlation between intimin, Tir, EspA, and/or EspB antibodies and fecal excretion of EHEC O157, O145, O111, O103, or O26 seropathotypes. The results indicated that serum antibody responses to EspB and EspA might be useful for first-line screening at the herd level for EHEC O157, O26, and most likely also for EHEC O103 infections. However, antibody responses against EspB are of less use for monitoring individual animals, since some EHEC-shedding animals did not show antibody responses and since serum antibody responses against EspB could persist for several months even when shedding had ceased. PMID:23563950

  10. Age and growth of European barbel Barbus barbus (Cyprinidae in the small, mesotrophic River Lee and relative to other populations in England

    Directory of Open Access Journals (Sweden)

    Vilizzi L.

    2013-08-01

    Full Text Available Suspected of being in decline, the European barbel Barbus barbus population of the River Lee, a heavily-modified river in South East England, has been the subject of investigations to identify factors associated with perceived population decreases. Population surveys between 1995 and 1999 captured a total of 912 individuals, and standard length (SL frequency analyses between years suggested that the population decline was not related to juvenile recruitment but rather to a recruitment bottleneck in fish 300–340 mm SL. This bottleneck probably results from insufficient available habitat suitable to this size class. Of the sampled fish, scales were removed from 764 and were used in a scale ageing exercise among three researchers. Analyses of their independent age estimates revealed variable interpretations, which arose from uncertainties relating to the difficulty of analysing scale patterns from relatively large, slow-growing fish. Nevertheless, error was within published acceptable margins, and age estimates revealed B. barbus in the river to age 10 years, lower than in many UK rivers. The SL-at-age growth curve was characterised by very fast growth in the initial years of life. Thus, the causal factors in the decline of this B. barbus population appear to have been in the adult life-stage habitat and were likely related to the loss of longitudinal connectivity, mainly due to the presence of water retention structures. River and aquatic ecosystem remediation strategies should therefore focus on enhancing longitudinal connectivity in conjunction with the ongoing improvement of water quality and ecosystem integrity.

  11. Long-term effects of Lee Silverman Voice Treatment on daily voice use in Parkinson's disease as measured with a portable voice accumulator.

    Science.gov (United States)

    Körner Gustafsson, Joakim; Södersten, Maria; Ternström, Sten; Schalling, Ellika

    2018-02-15

    This study examines the effects of an intensive voice treatment focusing on increasing voice intensity, LSVT LOUD ® Lee Silverman Voice Treatment, on voice use in daily life in a participant with Parkinson's disease, using a portable voice accumulator, the VoxLog. A secondary aim was to compare voice use between the participant and a matched healthy control. Participants were an individual with Parkinson's disease and his healthy monozygotic twin. Voice use was registered with the VoxLog during 9 weeks for the individual with Parkinson's disease and 2 weeks for the control. This included baseline registrations for both participants, 4 weeks during LSVT LOUD for the individual with Parkinson's disease and 1 week after treatment for both participants. For the participant with Parkinson's disease, follow-up registrations at 3, 6, and 12 months post-treatment were made. The individual with Parkinson's disease increased voice intensity during registrations in daily life with 4.1 dB post-treatment and 1.4 dB at 1-year follow-up compared to before treatment. When monitored during laboratory recordings an increase of 5.6 dB was seen post-treatment and 3.8 dB at 1-year follow-up. Changes in voice intensity were interpreted as a treatment effect as no significant correlations between changes in voice intensity and background noise were found for the individual with Parkinson's disease. The increase in voice intensity in a laboratory setting was comparable to findings previously reported following LSVT LOUD. The increase registered using ambulatory monitoring in daily life was lower but still reflecting a clinically relevant change.

  12. HYDRAULICS, LEE COUNTY, GEORGIA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  13. Contribution à l'étude de l'écologie et de la biologie des homoptères ravageurs des arbres fruitiers et autres plantes I.- Comparaison de l'évolution des populations d'Aleurodicus dispersus Russell (Hom.: Aleyrodidae sur agrumes et avocatier en République du Congo

    Directory of Open Access Journals (Sweden)

    Kiyindou, A.

    2002-01-01

    Full Text Available Contribution to the Knowledge of the Ecology and Biology of Homopterous Pests of Fruit Trees and other Plants I.- Comparaison of Evolution of Population of Aleurodicus dispersus Russell (Hom.: Aleyrodidae on Citrus and Avocado Trees in the Republic of the Congo. Aleurodicus dispersus Russell, a whitefly of neotropical origin, was introduced into Congo in the early '90. Since 1995, A. dispersus has developped the important populations on Citrus and avocado trees. The study of the population dynamic of this whitefly on Citrus and avocado trees indicates that the pest exhibits only four and three generation a year on Citrus and avocado trees respectively. Besides, an increase of the population of A. dispersus occurs in the dry season. However, rainfall reduces the insect population to a very low level. Its abundance indicates that during the rainy season, A. dispersus appears ealier underpinned for the first time and its significance assessed.

  14. Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson's disease: a pilot randomised controlled trial (PD COMM pilot).

    Science.gov (United States)

    Sackley, Catherine M; Smith, Christina H; Rick, Caroline E; Brady, Marian C; Ives, Natalie; Patel, Smitaa; Woolley, Rebecca; Dowling, Francis; Patel, Ramilla; Roberts, Helen; Jowett, Sue; Wheatley, Keith; Kelly, Debbie; Sands, Gina; Clarke, Carl E

    2018-01-01

    Speech-related problems are common in Parkinson's disease (PD), but there is little evidence for the effectiveness of standard speech and language therapy (SLT) or Lee Silverman Voice Treatment (LSVT LOUD®). The PD COMM pilot was a three-arm, assessor-blinded, randomised controlled trial (RCT) of LSVT LOUD®, SLT and no intervention (1:1:1 ratio) to assess the feasibility and to inform the design of a full-scale RCT. Non-demented patients with idiopathic PD and speech problems and no SLT for speech problems in the past 2 years were eligible. LSVT LOUD® is a standardised regime (16 sessions over 4 weeks). SLT comprised individualised content per local practice (typically weekly sessions for 6-8 weeks). Outcomes included recruitment and retention, treatment adherence, and data completeness. Outcome data collected at baseline, 3, 6, and 12 months included patient-reported voice and quality of life measures, resource use, and assessor-rated speech recordings. Eighty-nine patients were randomised with 90% in the therapy groups and 100% in the control group completing the trial. The response rate for Voice Handicap Index (VHI) in each arm was ≥ 90% at all time-points. VHI was highly correlated with the other speech-related outcome measures. There was a trend to improvement in VHI with LSVT LOUD® (difference at 3 months compared with control: - 12.5 points; 95% CI - 26.2, 1.2) and SLT (difference at 3 months compared with control: - 9.8 points; 95% CI - 23.2, 3.7) which needs to be confirmed in an adequately powered trial. Randomisation to a three-arm trial of speech therapy including a no intervention control is feasible and acceptable. Compliance with both interventions was good. VHI and other patient-reported outcomes were relevant measures and provided data to inform the sample size for a substantive trial. International Standard Randomised Controlled Trial Number Register: ISRCTN75223808. registered 22 March 2012.

  15. "¿Entiendes, con seguridad, lo que lees?" Hch 8, 30 Caminos de la hermenéutica de [en] la Escritura

    Directory of Open Access Journals (Sweden)

    Ignacio Chuecas Saldías

    2005-01-01

    Full Text Available El presente artículo busca ser una contribución para una hermenéutica bíblica práctica: es decir, no mira hacia la teoría de la interpretación, sino más bien hacia la praxis actual, especialmente en el campo de los estudios sincrónicos. Al mismo tiempo, pretende invitar al lector a conocer los métodos hermenéuticos propios de la tradición del Nuevo Testamento. Es a través de los caminos del midrash judeocristiano que nos acercamos a la praxis hermenéutica de los escritores bíblicos. El objetivo propuesto es llevado a cabo empleando como guía hermenéutica, a la vez que como laboratorio donde se ejemplifican los principios expuestos, el texto bíblico del encuentro del evangelista Felipe y el ministro de la reina de Etiopía (Hechos 8, 20-40. La pregunta de Felipe sirve de leitmotiv a este proceso: ¿entiendes, con certeza, lo que lees? Hermenéutica bíblica es siempre una manera de leer donde la escritura se interpreta a sí misma. El artículo presta especial atención a las categorías y herramientas de interpretación que se han desarrollado a partir de las nuevas impostaciones literarias en el campo de la exégesis bíblicaThe article attempts to make a contribution to the practical biblical hermeneutics focusing on the actual praxis, especially exploring the field of synchronic studies, rather than on the theory of interpretation. It also aims at offering an insight to the hermeneutic methods of the New Testament tradition, approaching the hermeneutic praxis of the biblical writers through the judeo-christian midrash paths. The accomplish such an objective, the author focuses on the biblical text of Philip's encounter with the minister of the queen of Ethiopia (Acts, 8, 20-40 as the hermeneutic guide and source to illustrate the principles being exposed. Philip's question "Can you really understand what you are reading?" serves as leitmotif to this process, as the biblical hermeneutics is a way of reading inwhich the

  16. Waste Conversion into n-Caprylate and n-Caproate: Resource Recovery from Wine Lees Using Anaerobic Reactor Microbiomes and In-line Extraction.

    Science.gov (United States)

    Kucek, Leo A; Xu, Jiajie; Nguyen, Mytien; Angenent, Largus T

    2016-01-01

    To convert wastes into sustainable liquid fuels and chemicals, new resource recovery technologies are required. Chain elongation is a carboxylate-platform bioprocess that converts short-chain carboxylates (SCCs) (e.g., acetate [C2] and n-butyrate [C4]) into medium-chain carboxylates (MCCs) (e.g., n-caprylate [C8] and n-caproate [C6]) with hydrogen gas as a side product. Ethanol or another electron donor (e.g., lactate, carbohydrate) is required. Competitive MCC productivities, yields (product vs. substrate fed), and specificities (product vs. all products) were only achieved previously from an organic waste material when exogenous ethanol had been added. Here, we converted a real organic waste, which inherently contains ethanol, into MCCs with n-caprylate as the target product. We used wine lees, which consisted primarily of settled yeast cells and ethanol from wine fermentation, and produced MCCs with a reactor microbiome. We operated the bioreactor at a pH of 5.2 and with continuous in-line extraction and achieved a MCC productivity of 3.9 g COD/L-d at an organic loading rate of 5.8 g COD/L-d, resulting in a promising MCC yield of 67% and specificities of 36% for each n-caprylate and n-caproate (72% for both). Compared to all other studies that used complex organic substrates, we achieved the highest n-caprylate-to-ncaproate product ratio of 1.0 (COD basis), because we used increased broth-recycle rates through the forward membrane contactor, which improved in-line extraction rates. Increased recycle rates also allowed us to achieve the highest reported MCC production flux per membrane surface area thus far (20.1 g COD/m 2 -d). Through microbial community analyses, we determined that an operational taxonomic unit (OTU) for Bacteroides spp. was dominant and was positively correlated with increased MCC productivities. Our data also suggested that the microbiome may have been shaped for improved MCC production by the high broth-recycle rates. Comparable abiotic

  17. Waste conversion into n-caprylate and n-caproate: resource recovery from wine lees using anaerobic reactor microbiomes and in-line extraction

    Directory of Open Access Journals (Sweden)

    Leo A. Kucek

    2016-11-01

    Full Text Available To convert wastes into sustainable liquid fuels and chemicals, new resource recovery technologies are required. Chain elongation is a carboxylate-platform bioprocess that converts short-chain carboxylates (SCCs (e.g., acetate C2 and n-butyrate C4 into medium-chain carboxylates (MCCs (e.g., n-caprylate C8 and n-caproate C6 with hydrogen gas as a side product. Ethanol or another electron donor (e.g., lactate, carbohydrate is required. Competitive MCC productivities, yields (product vs. substrate fed, and specificities (product vs. all products were only achieved previously from an organic waste material when exogenous ethanol had been added. Here, we converted a real organic waste, which inherently comprised of ethanol, into MCCs with n-caprylate as the target product. We used wine lees, which consisted primarily of settled yeast cells and ethanol from wine fermentation, and produced MCCs with a reactor microbiome. We operated the bioreactor at a pH of 5.2 and with continuous in-line extraction and achieved a MCC productivity of 3.9 g COD/L-d at an organic loading rate of 5.8 g COD/L-d, resulting in a promising MCC yield of 67% and specificities of 36% for each n-caprylate and n-caproate (72% for both. Compared to all other studies that used complex organic substrates, we achieved the highest n-caprylate-to-n-caproate product ratio of 1.0 (COD basis, because we used increased broth-recycle rates through the forward membrane contactor, which improved in-line extraction rates. Increased recycle rates also allowed us to achieve the highest reported MCC production flux per membrane surface area thus far (20.1 g COD/m2-d. Through microbial community analyses, we determined that an operational taxonomic unit (OTU for Bacteroides spp. was dominant and was positively correlated with increased MCC productivities. Our data also suggested that the microbiome may have been shaped for improved MCC production by the high broth-recycle rates. Comparable abiotic

  18. Status and trends of the rainbow trout population in the Lees Ferry reach of the Colorado River downstream from Glen Canyon Dam, Arizona, 1991–2009

    Science.gov (United States)

    Makinster, Andrew S.; Persons, William R.; Avery, Luke A.

    2011-01-01

    The Lees Ferry reach of the Colorado River, a 25-kilometer segment of river located immediately downstream from Glen Canyon Dam, has contained a nonnative rainbow trout (Oncorhynchus mykiss) sport fishery since it was first stocked in 1964. The fishery has evolved over time in response to changes in dam operations and fish management. Long-term monitoring of the rainbow trout population downstream of Glen Canyon Dam is an essential component of the Glen Canyon Dam Adaptive Management Program. A standardized sampling design was implemented in 1991 and has changed several times in response to independent, external scientific-review recommendations and budget constraints. Population metrics (catch per unit effort, proportional stock density, and relative condition) were estimated from 1991 to 2009 by combining data collected at fixed sampling sites during this time period and at random sampling sites from 2002 to 2009. The validity of combining population metrics for data collected at fixed and random sites was confirmed by a one-way analysis of variance by fish-length class size. Analysis of the rainbow trout population metrics from 1991 to 2009 showed that the abundance of rainbow trout increased from 1991 to 1997, following implementation of a more steady flow regime, but declined from about 2000 to 2007. Abundance in 2008 and 2009 was high compared to previous years, which was likely the result of increased early survival caused by improved habitat conditions following the 2008 high-flow experiment at Glen Canyon Dam. Proportional stock density declined between 1991 and 2006, reflecting increased natural reproduction and large numbers of small fish in samples. Since 2001, the proportional stock density has been relatively stable. Relative condition varied with size class of rainbow trout but has been relatively stable since 1991 for fish smaller than 152 millimeters (mm), except for a substantial decrease in 2009. Relative condition was more variable for larger

  19. O ENSINO DE MATEMÁTICA NOS ANOS INICIAIS DO ENSINO FUNDAMENTAL: O PROBLEMA DA FORMAÇÃO DO PROFESSOR E AS CONTRIBUIÇÕES DE LEE SHULMAN E DE V. V. DAVYDOV

    OpenAIRE

    Ferreira, Valdivina Alves; Freitas, Raquel Aparecida Marra da Madeira

    2014-01-01

    O objetivo deste texto é apresentar uma discussão crítica acerca da formação do professor que ensina matemática nos anos iniciais do Ensino Fundamental. Inicia-se pelo delineamento do problema das dificuldades de ensino e de aprendizagem de matemática, recorrentes nas pesquisas e nos discursos acadêmicos, destacando como um dos fatores a formação dos professores. Em seguida apresentam-se as contribuições de dois teóricos distintos, Lee Shulman e V. V Davydov, para o enfrentamento deste proble...

  20. MODIFICAÇÃO DO MÉTODO LEE SILVERMAN DE TRATAMENTO VOCAL NA DOENÇA DE PARKINSON: ANÁLISE PERCEPTIVO-AUDITIVA E ACÚSTICA COMPUTADORIZADA

    OpenAIRE

    Barros, Andréa Lopes de Souza Miranda de

    2006-01-01

    OBJETIVO: verificar a aplicabilidade do Lee Silverman Voice Treatment® numa freqüência diferenciada, em indivíduos portadores de DP, por meio de análise perceptivo-auditiva e acústica computadorizada vocal. PACIENTES E MÉTODO: o estudo foi realizado com 12 indivíduos portadores da DP classificados entre os graus 1 e 4 (escala Hoehn & Yahr), com queixas fonoaudiológicas, submetidos à modificação do LSVT® com aplicação em freqüência de duas vezes por semana, com duração de 45 ...

  1. Embodied Rhythm: Commentary on "The Contribution of Anthropometric Factors to Individual Differences in the Perception of Rhythm" by Neil P. McAngus Todd, Rosanna Cousins, and Christopher S. Lee

    Directory of Open Access Journals (Sweden)

    Bruno H. Repp

    2007-01-01

    Full Text Available Todd, Cousins, and Lee (2007 have presented some intriguing data suggesting that body size, as measured by standard anthropometric indices, is related to the preferred beat period in a perceptual task. Curiously, however, they did not find a significant sex difference, even though the women in their sample were clearly smaller than the men. Another recent study of preferred spontaneous tempo (McAuley et al., 2006 likewise failed to find a sex difference in a large sample of young adults. It is unclear why body size should have an effect only within each sex group.

  2. Time-Lapse Analysis of Methane Quantity in the Mary Lee Group of Coal Seams Using Filter-Based Multiple-Point Geostatistical Simulation.

    Science.gov (United States)

    Karacan, C Özgen; Olea, Ricardo A

    2013-08-01

    Coal seam degasification and its success are important for controlling methane, and thus for the health and safety of coal miners. During the course of degasification, properties of coal seams change. Thus, the changes in coal reservoir conditions and in-place gas content as well as methane emission potential into mines should be evaluated by examining time-dependent changes and the presence of major heterogeneities and geological discontinuities in the field. In this work, time-lapsed reservoir and fluid storage properties of the New Castle coal seam, Mary Lee/Blue Creek seam, and Jagger seam of Black Warrior Basin, Alabama, were determined from gas and water production history matching and production forecasting of vertical degasification wellbores. These properties were combined with isotherm and other important data to compute gas-in-place (GIP) and its change with time at borehole locations. Time-lapsed training images (TIs) of GIP and GIP difference corresponding to each coal and date were generated by using these point-wise data and Voronoi decomposition on the TI grid, which included faults as discontinuities for expansion of Voronoi regions. Filter-based multiple-point geostatistical simulations, which were preferred in this study due to anisotropies and discontinuities in the area, were used to predict time-lapsed GIP distributions within the study area. Performed simulations were used for mapping spatial time-lapsed methane quantities as well as their uncertainties within the study area. The systematic approach presented in this paper is the first time in literature that history matching, TIs of GIPs and filter simulations are used for degasification performance evaluation and for assessing GIP for mining safety. Results from this study showed that using production history matching of coalbed methane wells to determine time-lapsed reservoir data could be used to compute spatial GIP and representative GIP TIs generated through Voronoi decomposition

  3. Twin Legacies: Victor and Vincent McKusick/Twin Studies: Twinning Rates I; Twinning Rates II; MZ Twin Discordance for Russell-Silver Syndrome; Twins' Language Skills/Headlines: Babies Born to Identical Twin Couples; Identity Exchange; Death of Princess Ashraf (Twin); Yahoo CEO Delivers Identical Twins.

    Science.gov (United States)

    Segal, Nancy L

    2016-04-01

    The lives of the illustrious monozygotic (MZ) twins, Victor A. and Vincent L. McKusick, are described. Victor earned the distinction as the 'Father of Medical Genetics', while Vincent was a legendary Chief Justice of the Maine Supreme Court. This dual biographical account is followed by two timely reports of twinning rates, a study of MZ twin discordance for Russell-Silver Syndrome (RSS) and a study of twins' language skills. Twin stories in the news include babies born to identical twin couples, a case of switched identity, the death of Princess Ashraf (Twin) and a new mother of twins who is also Yahoo's CEO.

  4. Genetics Home Reference: Russell-Silver syndrome

    Science.gov (United States)

    ... 2 [updated 2011 Jun 2]. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Ledbetter N, Mefford HC, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): ...

  5. MAPPING THE UNIVERSE: THE 2010 RUSSELL LECTURE

    International Nuclear Information System (INIS)

    Geller, Margaret J.; Kurtz, Michael J.; Diaferio, Antonaldo

    2011-01-01

    Redshift surveys are a powerful tool of modern cosmology. We discuss two aspects of their power to map the distribution of mass and light in the universe: (1) measuring the mass distribution extending into the infall regions of rich clusters and (2) applying deep redshift surveys to the selection of clusters of galaxies and to the identification of very large structures (Great Walls). We preview the HectoMAP project, a redshift survey with median redshift z = 0.34 covering 50 deg 2 to r = 21. We emphasize the importance and power of spectroscopy for exploring and understanding the nature and evolution of structure in the universe.

  6. A new Russell model for selecting suppliers

    NARCIS (Netherlands)

    Azadi, Majid; Shabani, Amir; Farzipoor Saen, Reza

    2014-01-01

    Recently, supply chain management (SCM) has been considered by many researchers. Supplier evaluation and selection plays a significant role in establishing an effective SCM. One of the techniques that can be used for selecting suppliers is data envelopment analysis (DEA). In some situations, to

  7. Femmes aux petits soins : la fêlure d’un idéal dans deux nouvelles de F.S. Fitzgerald The Lees of Happiness et An Alcoholic Case

    OpenAIRE

    DELESALLE-NANCEY, Catherine

    2017-01-01

    Écrites à 17 ans d’intervalle, ces deux nouvelles de Fitzgerald mettent en scène des artistes dont la maladie pour l’un (« The Lees of Happiness ») et l’alcoolisme pour l’autre (« An Alcoholic Case ») ont eu raison des facultés créatrices. Pourtant, l’attention se porte moins sur les malades que sur celles qui les soignent, et embrassent ainsi un rôle traditionnellement dévolu aux femmes : l’épouse aimante sacrifiant tout pour son mari grabataire et l’infirmière dévouée investie d’une mission...

  8. Protective efficacy in mice of monovalent and trivalent live attenuated influenza vaccines in the background of cold-adapted A/X-31 and B/Lee/40 donor strains.

    Science.gov (United States)

    Jang, Yo Han; Lee, Eun-Young; Byun, Young Ho; Jung, Eun-Ju; Lee, Yoon Jae; Lee, Yun Ha; Lee, Kwang-Hee; Lee, Jinhee; Seong, Baik Lin

    2014-01-23

    Influenza virus continues to take a heavy toll on human health and vaccination remains the mainstay of efforts to reduce the clinical impact imposed by viral infections. Proven successful for establishing live attenuated vaccine donor strains, cold-adapted live attenuated influenza vaccines (CAIVs) have become an attractive modality for controlling the virus infection. Previously, we developed the cold-adapted strains A/X-31 and B/Lee/40 as novel donor strains of CAIVs against influenza A and B viruses. In this study, we investigated the protective immune responses of both mono- and trivalent vaccine formulations in the mouse model. Two type A vaccines and one type B vaccine against A/New Caledonia/20/99 (H1N1), A/Panama/2007/99 (H3N2), and B/Shangdong/7/97 in the background of the A/X-31 ca or B/Lee/40 ca were generated by a reassortment procedure and evaluated for their immunogenicity and protective efficacy. Each monovalent vaccine elicited high levels of serum antibodies and conferred complete protection against homologous wild type virus infection. As compared to the monovalent vaccines, trivalent formulation induced higher levels of type A-specific serum antibodies and slightly lower levels of type B-specific antibodies, suggesting an immunological synergism within type A viruses and an interference in the replication of type B virus. Relatively lower type B-specific immunogenicity in trivalent vaccine formulation could be effectively implemented by increasing the vaccine dose of influenza B virus. These results of immunogenicity, protection efficacy, and immunological synergism between type A vaccines provide an experimental basis for optimal composition of trivalent vaccines for subsequent developments of multivalent CAIVs against seasonal and pandemic influenza viruses. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Flux of nitrogen, phosphorus, and suspended sediment from the Susquehanna River Basin to the Chesapeake Bay during Tropical Storm Lee, September 2011, as an indicator of the effects of reservoir sedimentation on water quality

    Science.gov (United States)

    Hirsch, Robert M.

    2012-01-01

    Concentrations of nitrogen, phosphorus, and suspended sediment are measured at the U.S. Geological Survey streamgage at Conowingo Dam at the downstream end of the Susquehanna River Basin in Maryland, where the river flows into the Chesapeake Bay. During the period September 7-15, 2011, in the aftermath of Tropical Storm Lee, concentrations of these three constituents were among the highest ever measured at this site. These measurements indicate that sediment-storage processes behind the three dams on the lower Susquehanna River are evolving. In particular, they indicate that scouring of sediment (and the nitrogen and phosphorus attached to that sediment) may be increasing with time. Trends in flow-normalized fluxes at the Susquehanna River at Conowingo, Maryland, streamgage during 1996-2011 indicate a 3.2-percent decrease in total nitrogen, but a 55-percent increase in total phosphorus and a 97-percent increase in suspended sediment. These large increases in the flux of phosphorus and sediment from the Susquehanna River to the Chesapeake Bay have occurred despite reductions in the fluxes of these constituents from the Susquehanna River watershed upstream from the reservoirs. Although the Tropical Storm Lee flood event contributed about 1.8 percent of the total streamflow from the Susquehanna River to the Chesapeake Bay over the past decade (water years 2002-11), it contributed about 5 percent of the nitrogen, 22 percent of the phosphorus, and 39 percent of the suspended sediment during the same period. These results highlight the importance of brief high-flow events in releasing nitrogen, phosphorus, and sediment derived from the Susquehanna River watershed and stored in the Conowingo Reservoir to the Chesapeake Bay.

  10. 22nd September 2010 - Korean Minister of Education, Science and Technology J.-H. Lee signing the guest book and exchanging gifts with CERN Director-General R. Heuer and Head of International Relations F. Pauss; visiting ALICE exhibition with Collaboration Spokesperson J. Schukraft; accompanied throughout by Adviser R. Voss.

    CERN Multimedia

    Teams : M. Brice ; JC Gadmer

    2010-01-01

    22nd September 2010 - Korean Minister of Education, Science and Technology J.-H. Lee signing the guest book and exchanging gifts with CERN Director-General R. Heuer and Head of International Relations F. Pauss; visiting ALICE exhibition with Collaboration Spokesperson J. Schukraft; accompanied throughout by Adviser R. Voss.

  11. Observations of a thin near surface layer in an estuarine environment: An exceptional bloom of the dinoflagellate Akashiwo sanguinea in the Lee estuary (Lough Mahon), Co. Cork, in September 2010

    Science.gov (United States)

    O'Boyle, Shane; McDermott, Georgina

    2014-03-01

    Observations on the occurrence of an exceptional phytoplankton bloom in the Lee estuary, Co. Cork, in September 2010 are reported. A thin layer of phytoplankton dominated by the dinoflagellate Akashiwo sanguinea (Dinophyceae), with a cell concentration of 16,900 cells ml-1 and chlorophyll a concentration of 680 μg l-1, was observed at a depth of 1 m. The layer extended over a horizontal distance of 3 km and was located in the estuarine pycnocline. Levels of dissolved oxygen supersaturation were elevated at 190 (%) saturation (15.9 mg O2 l-1) and the highest biochemical oxygen demand associated with the bloom was greater than 25 mg O2 l-1. Using biovolume data to calculate carbon content, and a water exchange rate of 0.06 d-1 and dilution factor of 0.1, the potential oxygen demand following bloom collapse was estimated to be 7.22 mg O2 l-1. The potential impact of this thin layer on the water quality of the estuary is discussed.

  12. Lightcurve Results for 1318 Nerina, 222 Lermontov 3015 Candy, 3089 Oujianquan, 3155 Lee, 6410 Fujiwara, 6500 Kodaira, (8290) 1992 NP, 9566 Rykhlova, (42923) 1999 SR18, and 2001 FY

    Science.gov (United States)

    Clark, Maurice

    2007-03-01

    Lightcurve period and amplitude results for 10 minor planets are presented. The observations were made at 3 locations: the Montgomery College Observatory, Chiro Observatory, and the Rosemary Hill Observatory. (1318) Nerina: 2.536 ± 0.001 hr, 0.16 ± 0.02 mag. (2222) Lermontov: 4.344 ± 0.001 hr, 0.58 ± 0.01 mag. (3015) Candy: 4.265 ± 0.001 hr, 1.05 ± 0.01 mag. (3089) Oujianquan: 11.198 ± 0.003 hr, 0.45 ± 0.05 mag. (3155) Lee: 8.36 ± 0.01 hr, 0.4 ± 0.1 mag. (6410) Fujiwara: 7.008 ± 0.001 hr, 0.80 ± 0.02 mag. (6500) Kodaira: 5.496 ± 0.009 hr, 0.80 ± 0.02 mag. (8290) 1992 NP: 4.453 ± 0.001 hr, 0.58 ± 0.02 mag. (9566) Rykhlova: 8.800 ± 0.001 hr, 0.95 ± 0.02 mag. (42923) 1999 SR18: 8.392 ± 0.001 hr, 1.38 ± 0.05 mag. 2001 FY: 5.207 ± 0.005 hr, 0.45 ± 0.05 mag. Also reported are indefinite period results for four objects in the hope that they may be useful for future observers: 1110 Jaroslawa, 1720 Neils, 3872 Akirafuji, and 6790 Pingouin.

  13. Inglased puhkavad Haljalas toodetud patjadel / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2005-01-01

    TOP-i 1. koht. Ülevaade Briti perefirma filiaali, patju ja tekke valmistava Baltic Fibres OÜ tegevusest. Kommenteerib Haljala vallavanem Jüri Sikkut. Lisa: Baltic Fibres OÜ. Diagramm: Kasum 15 miljonit suurem kui mullu

  14. Uued elamupiirkonnad / Lee Taal, Gea Velthut

    Index Scriptorium Estoniae

    Taal, Lee

    1998-01-01

    Lühiinfot: projektijuht, valmis elamud, infrastruktuur, arhitektuurne kontseptsioon, ehitajad, arhitektid jm. Maarjamäe elamupiirkond (AB Harmin, AB Urbel ja Peil, Alver Trummal Arhitektid), Vabaõhukooli tee asum (Künnapu & Padrik), Lepiku küla Kloostrimetsas /Lepiku Kinnisvarahooldus), Raudalu asum Viljandi mnt. ääres (R-Konsult, I. Raud), Kodu 2001 (Nordprojekt, Jaak Kruusmägi), Tiskre Haaberstis (Arhitektuuribüroo Alis), Randvere tee (Nordprojekt), Veskimöldre (Koot ja Koot).

  15. Kahanev rahvaarv kasvatab rahumeelsust / Lee Kuan Yew

    Index Scriptorium Estoniae

    Lee Kuan Yew, 1923-

    2013-01-01

    Singapuri kauaaegne peaminister meenutab, et teise maailmasõja ajendiks oli Jaapani ja Saksamaa kõrgest sündimuskordajast (vastavalt 4,2 ja 2,6) tingitud ruumipuudus ja laienemisiha. Arvestades India (2,6) ja Aafrika riikide (4-7) vastavaid arve, küsib autor, mis meid nüüd ees ootab ja kas oleme selleks valmis

  16. FLOODPLAIN, LEE COUNTY, GEORGIA and INCORPORATED AREAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  17. Lee Kuan Yew: Master Builder of Singapore

    National Research Council Canada - National Science Library

    Exner, Philip J

    1996-01-01

    .... Few, however, have independence forced upon them as Singapore did. On August 9, 1965, after several stormy years attempting to integrate in a post-colonial federation, it was unexpectedly expelled from Malaysia...

  18. ' "Life is Movement": Vernon Lee and Sculpture'

    DEFF Research Database (Denmark)

    Østermark-Johansen, Lene

    2018-01-01

    How do living, breathing human bodies respond to the inert bodies of sculpture? This article examines some of the art-theoretical and psychological writings of Violet Paget (‘Vernon Lee’) and Clementina Anstruther-Thomson of the 1880s and 1890s in an attempt to map the evolution of their formalist...... from Lee’s early essays in Belcaro: Being Essays on Sundry Aesthetical Questions (1881) to the late collaborative volume Art and Man (1924)....

  19. Jaapani edumetoodika ka Eestis / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti 17. nov. lk. 28. Tootmissfääris kasutatavast Jaapani 20 võtme metoodikast loodab ettevõttele kasu saada lehtmetalli töötleva AS-i Favor Metaform nõukogu esimees Almar Proosi. Lisa: Mis on 20 võtit?

  20. DCS Terrain Submission for Lee County MS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix M: Data Capture Standards, describes the digital topographic data that was used to create...

  1. Floodplain Submission for Lee County, MS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  2. THE POLITICAL CRITIQUE OF SPIKE Lee's Bamboozled

    African Journals Online (AJOL)

    Admin

    INTRODUCTION Because slavery is the founding historical relationship between black and white in America many will argue, lingers in subterranean form to this day (Guerrero 1993: 03). Film and the African-American Image. As a form of ..... memory in modern cultural life” (01). Film becomes a cultural tool bearing popular ...

  3. Lee Kuan Yew: Master Builder of Singapore

    National Research Council Canada - National Science Library

    Exner, Philip J

    1996-01-01

    ... powerhouse has made the "Singapore Model" one of the most closely studied patterns among developing nations. Singapore enjoyed sustained growth and political stability during a period when other regional states experienced much turbulence...

  4. Lees- en spellingagterstande van leerders met serebrale ...

    African Journals Online (AJOL)

    The causes and characteristics of the reading and spelling deficits of learners with cerebral palsy (CP), as well as the working memory processing are discussed. Due to the vision, hearing and speech disabilities of these learners, the phonological loop in the working memory receives and rejects an unclear message, ...

  5. Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.

    Science.gov (United States)

    Bohacek, R S; McMartin, C

    1992-05-15

    The accessible surface, described by Lee and Richards (the L&R surface: J. Mol. Biol. 1971, 55, 379), has remarkably useful properties for displaying ligand-protein interactions. The surface is placed one van der Waals radius plus one probe radius away from the protein atoms. The ligands are displayed in skeletal form. With a suitable probe radius, those parts of the ligand in good van der Waals contact with the protein binding site are found superimposed on the L&R surface. Display of the surface using parallel contours therefore provides a very powerful guide for interactive drug design because only ligand atoms lying on or close to the surface are in low-energy contact. The ability of the surface to accurately display steric complementarity between ligands and proteins was optimized using data from small molecule crystal structures. The possibility of displaying the chemical specificity of the binding site was also investigated. The surface can be colored to give precise information about chemical specificity. Electrostatic potential, electrostatic gradient, and distance to hydrogen-bonding groups were tested as methods of displaying chemical specificity. The ability of these methods to describe the complementarity actually observed in the interior of proteins was compared. High-resolution crystal data for ribonuclease and trypsin was used. The environment surrounding extended peptide chains in the protein was treated as a virtual binding site. The peptide chain served as a virtual ligand. This large sample of experimental data was used to measure the correlation between type of ligand atom and the calculated property of the nearest binding site surface. The best correlation was obtained using hydrogen-bonding properties of the binding site. Using this parameter the surface could be divided into three separate zones representing the hydrophobic, hydrogen-bond-acceptor, and hydrogen-bond-donor properties of the binding site. The percentage of hydrophobic ligand

  6. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, RUSSELL COUNTY, KY

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  7. Outburst flood evolution at Russell Glacier, western Greenland

    DEFF Research Database (Denmark)

    Carrivick, Jonathan; Russell, Andrew; Ingeman-Nielsen, Thomas

    2013-01-01

    Outburst floods have produced a distinctive and widespread Quaternary record both onshore and offshore via widespread and intense geomorphological impacts, yet these impacts remain poorly understood due to a lack of modern analogues. This study therefore makes the first systematic quantification...... floods should consider the importance of including intermediary lakes. Modern hazard mitigation studies could usefully note the potential use of reservoirs as an outburst flood alleviation resource....

  8. Outburst flood evolution at Russell Glacier, western Greenland

    DEFF Research Database (Denmark)

    Carrivick, Jonathan L.; Turner, Andy G.D.; Russell, Andrew J.

    2013-01-01

    Glacial lake outburst floods have produced a distinctive and widespread Quaternary record both onshore and offshore via widespread and intense geomorphological impacts, yet these impacts remain poorly understood due to a lack of modern analogues. This study therefore makes a systematic quantifica......Glacial lake outburst floods have produced a distinctive and widespread Quaternary record both onshore and offshore via widespread and intense geomorphological impacts, yet these impacts remain poorly understood due to a lack of modern analogues. This study therefore makes a systematic...... of including intermediary lakes. Modern hazard mitigation studies could usefully note the potential use of reservoirs as an outburst flood alleviation resource....

  9. Historical Investigations of the Richard B. Russell Multiple Resource Area.

    Science.gov (United States)

    1981-11-01

    bottom of deir beds. Dem beds at de big house was so high dey had steps to walk up so dey could git in ’em. Oh, dey was pretty, all kivvered over wid...for this report. Dye’s stepdaughter Hester, nee Harper, also married and had children. She wed Moriah Gray and bore George, Sally, Lula (called Sissie

  10. A case of Silver–Russell syndrome (SRS): multiple pituitary ...

    Indian Academy of Sciences (India)

    Ham 1969; Albertsson-Wikland 1989; Chatelain 1993; Az- cona et al. 1998). The incidence of GHD, hypopituitarism in SRS is still controversial. GH insufficiency in low-birth weight syn- dromes has an incidence of 13–67% (Albertsson-Wikland. 1989; Rochiccioli et al. 1989; Stanhope et al. 1989; Bo- guszewski et al. 1995).

  11. An African appreciation of the Russell-Einstein Manifesto

    International Nuclear Information System (INIS)

    Dippenaar, N.

    1997-01-01

    The deadly nature of nuclear weapons, their devastating effects, both immediate and long term, oblige the whole mankind to work hard in achievement of nuclear-weapon-free world. African attitude in spite of its fair share of examples what horror and hopelessness war can lead to, is to proceed to do all possible to eradicate nuclear weapons from our world, pour all the energy and human resources into finding peaceful means to overcome the differences, and work towards a sustainable, more equitable world

  12. Rethinking Historiography in Russel Brownlee's Garden of the ...

    African Journals Online (AJOL)

    This paper asserts that, when it comes to approaching previously silenced South African histories (for example, those personal histories that are written out of the official record by colonial practices of archive and documentary record-keeping), literary attempts at historical reimagining can better gesture towards a felt ...

  13. 76 FR 23342 - Russell Investment Management Company, et al.;

    Science.gov (United States)

    2011-04-26

    ... either (a) a broker-dealer or other participant in the continuous net settlement system of the National... enhance the Fund's operating efficiency. To preserve maximum efficiency and flexibility, a Fund reserves... to eliminate fractional shares or lots that are not tradeable round lots, or (c) for temporary...

  14. A case of Silver–Russell syndrome (SRS): multiple pituitary ...

    Indian Academy of Sciences (India)

    The patient had normomethylation, and in addition hypopituitarism, with low levels of growth hormone (GH) (provocative testing before the start and after termination of GH treatment), thyroxin, TSH, FSH, LH and testosterone. The GH was given for six years, growth response was satisfactory and he reached an adult height ...

  15. The clotting action of Russell viper venom. 1954.

    Science.gov (United States)

    2016-03-03

    Samuel I. Rapaport made seminal contributions to our basic understanding of blood coagulation. This paper beautifully illustrates his scientific approach through characterization of the clotting activity of venom from Daboia russelii, distinguishing it from the brain “thromboplastic” activity used in the prothrombin time. Using plasma from patients with deficiencies of proconvertin (factor VII), proaccelerin (factor V), antihemophilic globulin (factor VIII), or Christmas factor (factor IX), Rapaport and colleagues demonstrated that the venom's clotting activity does not require factor VII, but does require factor V and lipid. Thus, by combining the venom clotting test with the quick clotting time (prothrombin time), it was possible to diagnose factor VII deficiency. The venom is now known to act by directly activating factor X, and a form of the clotting test is used in the diagnosis of lupus anticoagulants.

  16. Alfred Russel Wallace and the elimination of the unfit

    Indian Academy of Sciences (India)

    2012-03-23

    Mar 23, 2012 ... giving to the pure instincts of women the selective power in marriage. (Wallace 1894, p 87). Without making some numerical estimate of this kind it is impossible to realise the severity, of the struggle continually going on in nature and the resultant elimination of the unfit. (Wallace 1895, p 438). Accepting ...

  17. College of Natural Resources assists with oral rabies vaccination project

    OpenAIRE

    Davis, Lynn

    2006-01-01

    On August 8, 2006, the United States Department of Agriculture (USDA) Animal Plant and Health Inspection Service (APHIS), Wildlife Services (WS), will begin releasing approximately 300,000 Oral Rabies Vaccination (ORV) baits from low-flying aircraft and by car in Buchanan, Dickenson, Lee, Russell, Scott, Smyth, Tazewell, Washington, and Wise counties in southwestern Virginia.

  18. 77 FR 17465 - Georgia Power Company; Notice of Application for Amendment of License and Soliciting Comments...

    Science.gov (United States)

    2012-03-26

    .... Date Filed: February 10, 2012. d. Applicant: Georgia Power Company. e. Name of Project: Middle... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2177-090] Georgia Power... Counties, Georgia, and Lee and Russell Counties, Alabama. g. Filed Pursuant to: Federal Power Act, 16 U.S.C...

  19. Professional Military Development of Major General Ernest N. Harmon

    Science.gov (United States)

    2008-06-13

    Stubbs, Mary Lee and Stanley Russell Conner . Armor-Cavalry: Regular and Reserve, Lineage Series, Part I (Washington, D.C.: Government Printing...College 250 Gibbon Ave. Fort Leavenworth, KS 66027-2314 Defense Technical Information Center/OCA 825 John J. Kingman Rd., Suite 944 Fort Belvoir

  20. Study guide for Statistics for business and financial economics a supplement to the textbook by Cheng-Few Lee, John C. Lee and Alice C. Lee

    CERN Document Server

    Moy, Ronald L; Kao, Lie Jane

    2015-01-01

    This Study Guide accompanies Statistics for Business and Financial Economics, 3rd Ed. (Springer, 2013), which is a business statistics textbook that uses finance, economics, and accounting data throughout the book. This Study Guide contains unique chapter reviews for each chapter in the textbook, formulas, examples, and additional exercises to enhance topics and their application. Solutions are included so students can evaluate their own understanding of the material. With more real-life data sets than the other books on the market, this study guide and the textbook that it accompanies, give readers all the tools they need to learn material in class and on their own. The topics covered are immediately applicable to facing uncertainty and the science of good decision making in financial analysis, econometrics, auditing, production, operations, and marketing research. Students in business degree programs will find this material particularly useful in their other courses and future work.

  1. Cultura clássica, ópera e literatura na produção juvenil contemporânea: análise da obra La Traviata, por Lee Gyeong Hye, com ilustrações de Aurelia Fronty

    Directory of Open Access Journals (Sweden)

    Eliane Aparecida Galvão Ribeiro Ferreira

    2016-12-01

    Full Text Available Este texto tem por objetivo apresentar uma análise da obra La Traviata, adaptada por Lee Gyeong Hye (2012 e ilustrada por Aurelia Fronty, a partir da ópera clássica homônima de Giuseppe Verdi. Para a consecução do objetivo, busca-se apresentar uma reflexão fundamentada pela Estética da Recepção acerca do que propicia o prazer na leitura e quais elementos determinam o papel do leitor implícito. Constrói-se a hipótese de que a estratégia de Hye de resgatar uma ópera clássica e adaptá-la sob a forma de narrativa ilustrada para o jovem leitor, tanto lhe faculta contato com um texto atraente, lúdico e crítico que o conduzirá à reflexão, quanto amplia seus conhecimentos, por meio do resgate da memória cultural.

  2. Multiple mortality modeling in Poisson Lee-Carter framework

    OpenAIRE

    D'Amato, V.; Haberman, S.; Piscopo, G.; Russolillo, M.; Trapani, L.

    2016-01-01

    The academic literature in longevity field has recently focused on models for detecting multiple population trends (D'Amato et al., 2012b; Njenga and Sherris, 2011; Russolillo et al., 2011, etc.). In particular, increasing interest has been shown about "related" population dynamics or "parent" populations characterized by similar socioeconomic conditions and eventually also by geographical proximity. These studies suggest dependence across multiple populations and common long-run relationship...

  3. Die ontwikkeling van die ESSI-lees- en speltoets | Esterhuyse ...

    African Journals Online (AJOL)

    The ESSI reading and spelling test (Afrikaans and English) was developed to replace the well-known UCT reading and spelling test standardized in 1944. This measuring instrument was developed in four phases. This article deals with the development work performed during the first three phases. During phase 1, support ...

  4. Die ontwikkeling van lees- en speltoetse vir Sesotho-sprekende ...

    African Journals Online (AJOL)

    In this study, a reading and spelling test for the Sesotho-speaking learners in the elementary phase was developed and standardised. A Sesotho reading and spelling test was developed, which could be used to determine the reading and spelling skills of Grades 1–3 learners. The test indicated norms per quarter and could ...

  5. Psigometriese eienskappe van die ESSI-lees- en speltoets ...

    African Journals Online (AJOL)

    In drawing up the ESSI reading and spelling test, four phases were followed. In an earlier article, the development work that took place during the first three phases was discussed. This article focuses on the last phase during which the psychometric characteristics of the ESSI reading and spelling test were investigated.

  6. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, LEE COUNTY, FLORIDA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  7. Developing effective supervisors: Concepts of research | Lee | South ...

    African Journals Online (AJOL)

    Educating our early career researchers is becoming more complex. The range of doctoral degrees, the fast moving nature of knowledge, internationalisation, the demands of funding bodies and employers are all pulling on Ph.D. supervisors. The untrained Ph.D. supervisor will copy (or avoid copying) the way that they were ...

  8. Multiple myeloma in an Amur tiger ( Panthera tigris altaica ) | Lee ...

    African Journals Online (AJOL)

    The Amur tiger (Panthera tigris altaica) is an endangered tiger subspecies. An adult zoo-bred female was found collapsed, and died despite supportive treatment. Hematology and biochemistry showed pancytopenia and hyperglobulinemia, and serum protein electrophoresis revealed a monoclonal band in the β-globulin ...

  9. Book Review: Hospital and nursing yearbook | Lee | South African ...

    African Journals Online (AJOL)

    Abstract. Book Title: Hospital and nursing yearbook: Hospital and Nursing Yearbook for Southern Africa: Comprehensive Health Services Information for Southern Africa. 32nd ed. pp. 288. Cape Town: H. Engelhardt. 1992.

  10. Matthew's community and the Gentile mission / by Kukzin Lee

    OpenAIRE

    Lee, Kukzin

    2010-01-01

    Matthew contains seemingly contradictory passages with regard to the Gentiles and the Gentile mission. On the one hand, it seems that the Gentiles are disparaged and excluded from the missionary activities of Jesus' disciples. On the other hand, some Matthean passages imply the Matthean community's open attitude toward the Gentiles. Scholars have stressed one part of evidence over the other and come to the conclusion that either Matthew's community was extra muros or intra muros, respectively...

  11. Application of biologics to feedstuff | Lee | African Journal of ...

    African Journals Online (AJOL)

    ... transformed enzyme gene or raw material of feedstuff using biotechnology (e.g. fermentation) to enhance nutritive value. However, the availability of these biotechnological products shall be proved by the animal feeding trial. Keywords: Enzyme, feed additives, fermentation, probiotics. African Journal of Biotechnology Vol.

  12. Lees-om-te-leer: 'n studievaardigheid | Esterhuizen | Journal for ...

    African Journals Online (AJOL)

    Learners specially acquire knowledge by means of reading. The importance of this skill is emphasised with reference to reading strategies and the teaching thereof, as well as the development of critical and analytical thinking. Although it is not implicated that such teaching does not exist at all, the lack of a procedural and ...

  13. Kofi Annan und Tim Berners-lee preisen Informationsfreiheit

    CERN Multimedia

    Ermet, Monika

    2003-01-01

    The UN General Secretary and the Pioneer of WEB, will participate in Geneva at the WSIS with scholars from all the world. The World Summit on the Information Society was held in two phases. The first phase took place in Geneva hosted by the Government of Switzerland from 10 to 12 December 2003. It addressed the broad range of themes concerning the Information Society and adopted a Declaration of Principles and Plan of Action

  14. Adaptive Lee enhancement algorithm for processing drop_quality image

    Science.gov (United States)

    Wang, Xinsai; He, Jing; Li, Xue; He, Ming

    2007-12-01

    In order to transform image contrast and enhance vision effect the enhancement processing of image is need in the system of object recognition and automatic target tracking. The methods of image enhancement are more, for example, linearity, line segment, nonlinear, histogram equalization, histogram normalization, power exponent, local gray-level statistic feature and so on. Through analyzing gradient characteristic of image gray-level, in this paper the method of image enhancement is presented based on the local statistic arithmetic of neighborhood grads even. Experiment results show the correctness and utility of this method.

  15. 2014 Lee County, GA DMC 4-Band 8 Bit Imagery

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of six-inch pixel resolution, natural color orthoimages covering the urban area footprint. An orthoimage is remotely sensed image data in...

  16. Lee as Critical Thinker: The Example of the Gettysburg Campaign

    Science.gov (United States)

    2012-05-04

    the preservation of the Union were all at stake. Most scholars agree that in retrospect, the Battle of Gettysburg was one of the turning points in...could prevent reinforcements from the right. Bottom line, the object of the second day was the Peach Orchard and ultimately Cemetery Hill. Contrary...Wheatfield and Peach Orchard were taken but the Union held Little Round Top. Poor coordination and delays were factors in the failure to break through

  17. Een teks - meerdere betekenisse: Hoe lees ons die Bybel?

    Directory of Open Access Journals (Sweden)

    Ernest van Eck

    2008-03-01

    Full Text Available One text – multiple meanings: How do we read the Bible? This article discusses three ways of reading the Bible that are evident in the current theological debate in South Africa: a fundamentalist, foundationalist and critical reading. A brief description and evaluation of the three reading strategies are given. It is indicated that a fundamentalist reading of the Bible essentially operates with a canon in the canon, and a foundationalist reading with a canon outside the canon. A critical reading, which roots can be traced back to the Reformation, is put forward as possibly a more responsible way of reading the Biblical text, especially since it takes cognizance of the historical and cultural distance between text and reader. It is argued that readers who take this “differentness” seriously, are enabled to read the Bible afresh and anew, especially in terms of some burning ethical questions of our day. Attention is also given to a critical reading of metaphorical language of the Bible.

  18. Aspectual auxiliary verbs in Xitsonga | Lee | Stellenbosch Papers in ...

    African Journals Online (AJOL)

    Stellenbosch Papers in Linguistics Plus. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 48 (2015) >. Log in or Register to get access to full text downloads.

  19. 76 FR 30947 - Stephen Lee Seldon: Debarment Order

    Science.gov (United States)

    2011-05-27

    ... convicted of a felony under Federal law for conduct relating to the regulation of any drug product under the... conduct relating to the regulation of a drug product. The factual basis for those convictions is as... felonies under Federal law for conduct relating to the regulation of a drug product under the FD&C Act. The...

  20. Suudab ta pensionäre toita? / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2000-01-01

    Kuna Eesti rahvastiku vananemine suurendab ülalpeetavate hulka ühiskonnas, siis ei saa praegust solidaarsuspõhimõttel rajanevat pensionisüsteemi enam kasutada, vaid tuleb pensionisüsteemi muuta. Pensionisüsteemi koormusest ja kohustuslikust kogumispensionist. Diagrammid: Eesti rahvaarv 1999-2050; rahvastikupüramiid 1997, 2025 ja 2050; kaua saavad/said mehed ja naised pensionipõlve nautida 1960-2010; vajaliku sotsiaalmaksu % palgast 2000-2070; keskmise pensioni ja brutopalga suhe 1965-2000; vanurite osatähtsus 1881-2030; keskmine eluiga 1950-2050. Kommenteerivad E. Nestor, K. Katus, L. Sakkeus

  1. Occipital condylar dysplasia in a Jacob lamb ( Ovis aries ) | Lee ...

    African Journals Online (AJOL)

    multihorned) phenotype. We describe a four-horned Jacob lamb that exhibited progressive congenital hindlimb ataxia and paresis, and was euthanased four weeks post-partum. Necropsy and CT-scan revealed deformity and asymmetry of the ...

  2. Tim Ingold and Jo Lee Vergunst, eds., . Aldershot, Ashgate ...

    African Journals Online (AJOL)

    ANBR

    foregrounding the topic of 'ways of walking', one that is often relegated to footnotes or to short sections on ... Malaysia, who are lowland peoples living close to Malay villages where supplies can be bought and where they ... (slave trade) and contemporary (tourist walking trails and encountering tourists as she walks with the ...

  3. Distribution of conjunctive and disjunctive forms in Xitsonga | Lee ...

    African Journals Online (AJOL)

    Xitsonga follows these basic patterns observed in other Bantu languages, but previous theories cannot explain all of the cases in which the conjunctive and disjunctive forms are distinguished. In previous work, three major approaches have been proposed: the constituency approach, the focus-based approach, and the ...

  4. Diamond Jubi lee of the Academy Mid-Year Meeting

    Indian Academy of Sciences (India)

    1994-07-01

    Jul 1, 1994 ... The lecturer began by characterizing their work as a clock comparison experiment leading to the first experimental detection of gravitational radiation - a prediction of general relativity made by Einstein as early as 1916. In principle, a rotating dumb bell in the laboratory would lose energy by this mechanism, ...

  5. "You see how good-looking Lee Ann is!"

    DEFF Research Database (Denmark)

    Spanger, Marlene

    2012-01-01

    a poststructuralist feminist perspective, arguing that looks and bodily practices, based on different constellations of gender and sexuality and race and nationality, are important for the research situation. Bringing in two different examples, the article analyses the field relations, and the implied power relations......By investigating the case of female Thai migrants selling sexual services in Denmark, I argue that ‘the victim’ versus ‘the empowered subject’ is an undesirable binary for analysing how female migrants perform gendered subject positions in their everyday life. The article suggests......, - between the researcher(s) and the studied subjects that are constituted through gender, sexuality, race and nationality. These relations form the premises for producing material....

  6. Editorial: A message of thanks | Lee | Ostrich: Journal of African ...

    African Journals Online (AJOL)

    Ostrich: Journal of African Ornithology. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 87, No 3 (2016) >. Log in or Register to get access to full text downloads.

  7. Harry Lee Parker and paroxysmal dysarthria and ataxia.

    Science.gov (United States)

    Klaas, James P; Burkholder, David B; Singer, Wolfgang; Boes, Christopher J

    2013-01-15

    To review descriptions of paroxysmal dysarthria and ataxia in multiple sclerosis (MS), with special attention given to Parker and his 1946 case series. Evaluation of original publications describing paroxysmal dysarthria and ataxia, bibliographic information, writings, and unpublished letters from the Mayo Clinic Historical Unit. In 1940, Störring described a patient with MS with paroxysmal symptoms that included dizziness and trouble speaking, but also unilateral extremity weakness. In 1946, Parker published a series of 11 patients with paroxysmal dysarthria and ataxia. Six of these patients had MS, and he recognized this phenomenon as a manifestation of the disease. The term "paroxysmal dysarthria and ataxia" was first used in 1959 by Andermann and colleagues. Since that time, paroxysmal dysarthria and ataxia has become a well-recognized phenomenon in MS. More recent reports have suggested that the responsible lesion is located in the midbrain, near or involving the red nucleus. Parker was the first to accurately describe paroxysmal dysarthria and ataxia in patients with MS.

  8. "Sê sjibbolet": 'n intertekstuele lees | van Wyk | Tydskrif vir letterkunde

    African Journals Online (AJOL)

    Sê sjibbolet: an intertextual reading. This article pursues an intertextual reading of Adam Small's collection of poetry Sê sjibbolet (“Say shibboleth”). The collection is read alongside texts that refer to “shibboleth” in their titles i.e. works by Paul Celan, Jacques Derrida and Doris Salcedo. The analysis draws on the readings ...

  9. Diamond Jubi lee of the Academy Mid-Year Meeting

    Indian Academy of Sciences (India)

    1994-07-01

    Jul 1, 1994 ... and was the recipient of the 1977 Award of tt.e. Federation of Indian Chambers of Commerce arid. Industry. He was a Visiting Professor at the Indian. Institute of Science, Bangalore for 3 years after his retirement from MIDHANI in 1979, and. Technical Director of Kamani Metals and Alloys. Ltd. for a year in ...

  10. 78 FR 37788 - In the Matter of: Juan Ricardo Puente-Paez, Inmate Number #05086-379, FCI McDowell, Federal...

    Science.gov (United States)

    2013-06-24

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security In the Matter of: Juan Ricardo Puente-Paez... Commerce for Industry and Security. The appeal must be filed within 45 days from the date of this Order and....S.C. 793, 794 or 798; section 4(b) of the Internal Security Act of 1950 (50 U.S.C. 783(b)), or...

  11. Definition of Aviation Turbine Fuel Contamination under Simulated Combat Conditions

    Science.gov (United States)

    1977-09-01

    S ’i’ DEFINITION OF AVIATION TURBINE FUEL CONTAMINATION UNDER SIMULATED COMBAT CONDITIONS FINAL REPORT AFLRL NO. 90 by q J. A. Russell J. DI . Tosh F...Logistics Center U.S. Army Armament CommandAtn TLMI A ln RSAi4-SM Fort Lee, Virginia 23801 DiISAR-PP Commander Rock ilJand, lllinoi½ 61201 U.S. Army

  12. Music Information Seeking Behaviour Poses Unique Challenges for the Design of Information Retrieval Systems. A Review of: Lee, J. H. (2010. Analysis of user needs and information features in natural language queries seeking music information. Journal of the American Society for information Science and Technology, 61, 1025-1045.

    Directory of Open Access Journals (Sweden)

    Cari Merkley

    2010-12-01

    encompassed 57 different features, a small number of features dominated, with seven features used in over 25% of the queries posted and 33 features appearing in less than 10%. The seven most common features were person name, title, date, genre, role, lyric, and place reference.Lee categorized most of the queries as “known-item searches,” even though at times users provided incorrect information and many were looking for information about the musical item but not the item itself (p. 1035. Other interesting features identified by the author were the presence of “dormant searches,” long standing questions a user had about a musical item, sometimes for years, which were reawakened by hearing the song again or other events (p. 1037. Multiple versions of musical works and the provision of information gleaned third hand by users were also identified as complicating factors in correctly meeting musical information needs.Conclusion – While certain types of questions dominated among music queries posted on the Google Answers service, there were a wide variety of music information needs expressed by users. In some cases, the features provided by the user as clues to answering the query were very personal, and related to the context. in which they encountered the work or the mood a particular work or artist evoked. Such circumstances are not currently or adequately covered by existing bibliographic record standards, which focus on qualities inherent in the music itself. The author suggests that user context should play a greater role in the testing and development of music information retrieval systems, although the instability and variability of this type of information is acknowledged. In some cases this context could apply to other works (film, television, etc. in which a musical work is featured. Another potential implication for music information retrieval system development is a need to re-evaluate the terminology employed in testing to ensure that it is the language most

  13. RNN with Russell's Circumplex Model for Emotion Estimation and Emotional Gesture Generation

    OpenAIRE

    Tsujimoto, Takuya; Takahashi, Yasutake; Takeuchi, Shouhei; Yoichiro Maeda,

    2016-01-01

    Interactive Emotion Communication (IEC) has been proposed[1] and studied so far. IEC consists of three processes,recognition of human emotion, generation of robot emotion, and expression of robot emotion. Conventional studies designed those processes by hand one by one. This report proposes a comprehensive system that learns human emotion recognitionand robot emotion expression both. The proposed system is a recurrent neural network introducing Russell’s circumplex model explicitly and learns...

  14. Preliminary studies of the CHIM electrogeochemical method at the Kokomo Mine, Russell Gulch, Colorado

    Science.gov (United States)

    Smith, D.B.; Hoover, D.B.; Sanzolone, R.F.

    1993-01-01

    The CHIM electrogeochemical exploration technique was developed in the former Soviet Union about 20 years ago and is claimed to be effective in exploration for concealed mineral deposits that are not detectable by other geochemical or geophysical techniques. The method involves providing a high-voltage direct current to an anode and an array of special collector cathodes. Cations mobile in the electric field are collected at the cathodes and their concentrations determined. The U.S. Geological Survey started a study of the CHIM method by conducting tests over a precious- and base-metal-bearing quartz vein covered with 3 m of colluvial soil and weathered bedrock near the Kokomo Mine, Colorado. The tests show that the CHIM method gives better definition of the vein than conventional soil geochemistry based on a total-dissolution technique. The CHIM technique gives reproducible geochemical anomaly patterns, but the absolute concentrations depend on local site variability as well as temporal variations. Weak partial dissolutions of soils at the Kokomo Mine by an enzyme leach, a dilute acetic acid leach, and a dilute hydrochloric acid leach show results comparable to those from the CHIM method. This supports the idea that the CHIM technique is essentially a weak in-situ partial extraction involving only ions able to move in a weak electric field. ?? 1993.

  15. Energetic properties of stellar pulsations across the Hertzsprung-Russell diagram

    Directory of Open Access Journals (Sweden)

    Daszyńska-Daszkiewicz Jadwiga

    2015-01-01

    Full Text Available I will review types of modes which are observed in stars with different masses and on various evolutionary stages. In particular, I will focus on energetic aspects of oscillation modes, i.e., excitation, distribution of kinetic energy, mode amplitude and lifetime.

  16. Positive acculturation conditions and work related outcomes : the mediating role of integration / Russell A.L.

    OpenAIRE

    Russell, Abram Laurie

    2011-01-01

    Multiculturalism has emerged to challenge liberalism as an ideological solution in coping with ethnic diversity. Inter–ethnic group contact amongst individuals of different cultures is defined as acculturation. Acculturation is an experience from different cultural encounters between employees and their work environments where organisational socialization is a prerequisite to becoming accustomed to different cultural conditions. Acculturation orientation is related to well–bein...

  17. Optic neuritis caused by canine distemper virus in a Jack Russell terrier

    Science.gov (United States)

    Richards, Tara R.; Whelan, Nick C.; Pinard, Chantale L.; Alcala, Fernanda Castillo; Wolfe, Katheryn C.

    2011-01-01

    An atypical case of canine distemper (CD) was diagnosed in a vaccinated healthy adult dog. The patient was presented circling, seizuring, and blind. Postmortem examination resulted in a diagnosis of CD. Optic neuritis was diagnosed, a finding not previously described in the context of CD virus infection presenting solely with neurological signs. PMID:21731093

  18. A new cycle of jökulhlaups at Russell Glacier, Kangerlussuaq, West Greenland

    DEFF Research Database (Denmark)

    Russell, Andrew J.; Carrivick, Jonathan L.; Ingeman-Nielsen, Thomas

    2011-01-01

    that permits incomplete sealing of jokulhlaup conduitsbetween lake drainage events. Additionally, we demonstrate that the passage of jokulhlaups through aninterlinked system of proglacial bedrock basins produces significant attenuation of peak dischargedownstream. We highlight that improved understanding...

  19. 78 FR 30941 - Frank Russell Company, et al.; Notice of Application

    Science.gov (United States)

    2013-05-23

    ... RIF is comprised of ten separate registered funds, each with its own investment objective, policies... separate funds in registration, each with its own investment objective, policies and restrictions.\\1\\ \\1... development of the investment program for the Fund all in accordance with the investment objectives, policies...

  20. The complete mitochondrial genome of a spiraling whitefly, Aleurodicus dispersus Russell (Hemiptera: Aleyrodidae).

    Science.gov (United States)

    Ming-Xing, Lu; Zhi-Teng, Chen; Wei-Wei, Yu; Yu-Zhou, Du

    2017-03-01

    We report the complete mitochondrial genome (mitogenome) of a spiraling whitefly, Aleurodicus dispersus (Hemiptera: Aleyrodidae). The 16 170 bp long genome consists of 13 protein-coding genes, 20 transfer RNAs, 2 ribosomal RNAs, and a control region. The A. dispersus mitogenome also includes a cytb-like non-coding region and shows several variations relative to the typical insect mitogenome. A phylogenetic tree has been constructed using the 13 protein-coding genes of 12 related species from Hemiptera. Our results would contribute to further study of phylogeny in Aleyrodidae and Hemiptera.

  1. PENGARUH LINGKUNGAN TOKO TERHADAP KEADAAN EMOSIONAL DAN PERILAKU PEMBELIAN IMPULSIF KONSUMEN PENGUJIAN MODEL MEHRABIAN-RUSSELL

    Directory of Open Access Journals (Sweden)

    Febrina Annisa Fauziyah

    2018-02-01

    Full Text Available This study aims to analyze the influence of store environment on impulse buying behavior with emotional states as intervening variable using Mehrabian-Russell’s model. The store environment variables in this study include time availability, atmospheric factors, presence of others, and perceived crowdness. Using Mehrabian-Russell’s model, it is hypothesized that emotional state mediates the effects of store environment variables on impulse buying behavior as a dependent variable. The object in this study is Matahari Department Store in Yogyakarta. Sample of 166 respondents were selected by using purposive sampling method. Data were collected by using field survey technique. Normality, validity and reliability tests were conducted to test the quality of research instruments. The data analysis was conducted by using multiple linear regressions to test the research hypothesis. Results showed that atmospheric factors. as predicted, positively affect the emotional states. While perceived crowdness, consistent to the hypothesis, negatively affect the emotional states. The emotional states also positively affects the impulse buying behavior. The hypothesis of time availability and presence of others were not supported in this research. The findings of this research indicate that creating a proper atmospheric factors and creating a convenience store lay out to avoid crowdness are essential to stimulate impulse buying behavior.

  2. [Silver-Russell syndrome (hemihypertrophy) and cor triatriatum in a newborn].

    Science.gov (United States)

    Ríos-Méndez, Raúl Enrique; Montero-Monar, Hernán Eduardo; Pernández-Alvarado, Antonio Pedro; Hidalgo-Flores, Einstein Gustavo

    2015-06-01

    Hemihypertrophy syndrome and cor triatriatum are extremely rare pathologies. Hemihypertrophy is defined as complete or partial overgrowth of one of the hemibodies. Cor triatriatum is a congenital heart disease characterized by a membrane which separates the left atrium into two chambers; if that membrane has a restrictive hole, it causes obstruction to blood passage from the pulmonary veins into the left ventricle causing hypertension and pulmonary edema. In this context, the patent ductus arteriosus can act as a means of decompression of the pulmonary circuit, because it allows the blood passage from the pulmonary artery to the aorta. We report a patient with Silver-Rusell syndrome (hemihypertrophy), cor triatriatum and ductus arteriosus with reverse flow. To our knowledge, this association of rare pathologies and this clinical presentation have not been described previously.

  3. 77 FR 26781 - Charles M. Russell National Wildlife Refuge and UL Bend National Wildlife Refuge, MT

    Science.gov (United States)

    2012-05-07

    ... diverse as the topography and includes Rocky Mountain elk, mule deer, white-tailed deer, pronghorn, Rocky Mountain bighorn sheep, sharp-tailed grouse, greater sage-grouse, Sprague's pipit, black-footed ferrets... suitable for Rocky Mountain bighorn sheep would be identified, and new populations would be established...

  4. 75 FR 54381 - Charles M. Russell National Wildlife Refuge and UL Bend National Wildlife Refuge, MT

    Science.gov (United States)

    2010-09-07

    ..., and badlands. Wildlife is as diverse as the topography and includes Rocky Mountain elk, mule deer, white-tailed deer, pronghorn, Rocky Mountain bighorn sheep, sharp-tailed grouse, prairie dogs, and more... on the Refuge. Additional habitat suitable for Rocky Mountain bighorn sheep would be identified, and...

  5. 77 FR 67829 - Charles M. Russell National Wildlife Refuge and UL Bend National Wildlife Refuge, MT...

    Science.gov (United States)

    2012-11-14

    ... completed a thorough analysis of the environmental, social, and economic considerations associated with our... C--Public Use and Economic Use Emphasis, and Alternative D--Ecological Processes Emphasis. After... alternative D and in cooperation with our partners, we would use natural, dynamic, ecological processes, and...

  6. A new cycle of jökulhlaups at Russell Glacier, Kangerlussuaq, West Greenland

    DEFF Research Database (Denmark)

    Russell, Andrew J.; Carrivick, Jonathan L.; Ingeman-Nielsen, Thomas

    2011-01-01

    that permits incomplete sealing of jokulhlaup conduitsbetween lake drainage events. Additionally, we demonstrate that the passage of jokulhlaups through aninterlinked system of proglacial bedrock basins produces significant attenuation of peak dischargedownstream. We highlight that improved understanding...... of jokulhlaup dynamics requires accurateinformation about ice-dammed lake volume and ice-proximal jokulhlaup discharge....

  7. Deciphering the evolution of birdwing butterflies 150 years after Alfred Russel Wallace

    Science.gov (United States)

    Condamine, Fabien L.; Toussaint, Emmanuel F. A.; Clamens, Anne-Laure; Genson, Gwenaelle; Sperling, Felix A. H.; Kergoat, Gael J.

    2015-01-01

    One hundred and fifty years after Alfred Wallace studied the geographical variation and species diversity of butterflies in the Indomalayan-Australasian Archipelago, the processes responsible for their biogeographical pattern remain equivocal. We analysed the macroevolutionary mechanisms accounting for the temporal and geographical diversification of the charismatic birdwing butterflies (Papilionidae), a major focus of Wallace’s pioneering work. Bayesian phylogenetics and dating analyses of the birdwings were conducted using mitochondrial and nuclear genes. The combination of maximum likelihood analyses to estimate biogeographical history and diversification rates reveals that diversity-dependence processes drove the radiation of birdwings, and that speciation was often associated with founder-events colonizing new islands, especially in Wallacea. Palaeo-environment diversification models also suggest that high extinction rates occurred during periods of elevated sea level and global warming. We demonstrated a pattern of spatio-temporal habitat dynamics that continuously created or erased habitats suitable for birdwing biodiversity. Since birdwings were extinction-prone during the Miocene (warmer temperatures and elevated sea levels), the cooling period after the mid-Miocene climatic optimum fostered birdwing diversification due to the release of extinction. This also suggests that current global changes may represent a serious conservation threat to this flagship group. PMID:26133078

  8. Reflections on the social responsibility of scientists: Before and after the Russell-Einstein Manifesto

    International Nuclear Information System (INIS)

    Toyoda, Toshiyuki

    1997-01-01

    A series of actions undertaken by scientists concerned with their social responsibilities in the field of nuclear research and development are cited. Sadly, despite extraordinary efforts of those who tried to enlighten the general public, the world moved inexorably towards the fierce nuclear arms race. As a conclusion of the attitude of japanese scientists, the statement of the Kyoto Conference of Scientists issued in 1962 is cited: 'As the country which has experienced the disastrous effects of nuclear weapons, and which openly renounced war in its constitution, Japanese in a position to make a special contribution to word peace. We are convinced today, when the danger of the destruction of the human race by nuclear warfare is growing ever more serious, Article 9 of the japanese Constitution has a new significance, even greater than when the Constitution was first adopted. At the same time, we wish to emphasize once again our own responsibility for the maintenance of peace'

  9. 76 FR 7590 - Bruss North America Russell Springs, Kentucky; Notice of Revised Determination on Reconsideration

    Science.gov (United States)

    2011-02-10

    ... sold automobile parts and component parts for a firm that employed a worker group eligible to apply for... with the aforementioned firm, with respect to automobile parts and components sold to the firm... the subject firm, who are engaged in employment related to the supply of automobile parts and...

  10. Situk River Hydrology Following Closure of Russell Fiord by Hubbard Glacier

    Science.gov (United States)

    2011-03-01

    Preface This report was prepared by Dr. Steven F. Daly, Carrie Vuyovich, and Da- vid Finnegan, Remote Sensing/GIS and Water Resources Branch, Cold...report was provided by the Alaska District, Corps of Engineers. The authors wish to thank George Kalli, Patrick Fitzgerald, Da- vid Williams, Nathan...Alaska Department of Fish and Game 2009). The Si- tuk River provides a large portion of the economy of Yakutat. It is esti- mated that 85% of the

  11. 77 FR 14561 - Tribal Consultation Sessions-Administrative Organizational Assessment Draft Report...

    Science.gov (United States)

    2012-03-12

    ... McDowell Resort 2012. Hotel, 10438 N. Fort McDowell Road, Scottsdale/Fountain Hill, AZ 85264, (480) 789... description of each of the topics is provided below. Further information is available at: http://www...

  12. Neoleptonema yongpilii E.-Y. Lee & I.K. Lee, gen. et sp. nov. (Phaeophyceae), based on morphological characters and RuBisCO spacer sequences

    DEFF Research Database (Denmark)

    Lee, E.-Y.; Pedersen, Poul Møller; Lee, I.K.

    2002-01-01

    Elachistaceae, Neoleptonema yongpilii gen. et sp. nov., phylogenetic relationships, plurilocular sporangia, RuBisCO spacer sequences......Elachistaceae, Neoleptonema yongpilii gen. et sp. nov., phylogenetic relationships, plurilocular sporangia, RuBisCO spacer sequences...

  13. Interstellar Initiative Web Page Design

    Science.gov (United States)

    Mehta, Alkesh

    1999-01-01

    This summer at NASA/MSFC, I have contributed to two projects: Interstellar Initiative Web Page Design and Lenz's Law Relative Motion Demonstration. In the Web Design Project, I worked on an Outline. The Web Design Outline was developed to provide a foundation for a Hierarchy Tree Structure. The Outline would help design a Website information base for future and near-term missions. The Website would give in-depth information on Propulsion Systems and Interstellar Travel. The Lenz's Law Relative Motion Demonstrator is discussed in this volume by Russell Lee.

  14. Injury profile of non-contact sports for Perak SUKMA athletes | Lee ...

    African Journals Online (AJOL)

    The purpose of this study is to identify the injury profile of non-contact sports among Perak SUKMA athletes. The data from this injury is examined based on the five research questions which are nature of injury, body part, severity of injury (mild, moderate, severe), types of injury (acute or chronic), and factors of injury.

  15. Mabel Lee and Louise Pound: The University of Nebraska's Battle Over Women's Intercollegiate Athletics

    National Research Council Canada - National Science Library

    Kristi, Lowenthal

    1999-01-01

    Mirroring a cultural shift that brought the American middle class from the Victorian era into the modern era, women's intercollegiate sports encountered stiff resistance from the two overlapping social groups...

  16. St Joseph's Hospital, Bon Secours Care Village, Mount Desert, Lee Road, Cork.

    LENUS (Irish Health Repository)

    Farrell, Eric

    2011-01-31

    Abstract Background Bone grafts are required to repair large bone defects after tumour resection or large trauma. The availability of patients\\' own bone tissue that can be used for these procedures is limited. Thus far bone tissue engineering has not lead to an implant which could be used as alternative in bone replacement surgery. This is mainly due to problems of vascularisation of the implanted tissues leading to core necrosis and implant failure. Recently it was discovered that embryonic stem cells can form bone via the endochondral pathway, thereby turning in-vitro created cartilage into bone in-vivo. In this study we investigated the potential of human adult mesenchymal stem cells to form bone via the endochondral pathway. Methods MSCs were cultured for 28 days in chondrogenic, osteogenic or control medium prior to implantation. To further optimise this process we induced mineralisation in the chondrogenic constructs before implantation by changing to osteogenic medium during the last 7 days of culture. Results After 8 weeks of subcutaneous implantation in mice, bone and bone marrow formation was observed in 8 of 9 constructs cultured in chondrogenic medium. No bone was observed in any samples cultured in osteogenic medium. Switch to osteogenic medium for 7 days prevented formation of bone in-vivo. Addition of β-glycerophosphate to chondrogenic medium during the last 7 days in culture induced mineralisation of the matrix and still enabled formation of bone and marrow in both human and rat MSC cultures. To determine whether bone was formed by the host or by the implanted tissue we used an immunocompetent transgenic rat model. Thereby we found that osteoblasts in the bone were almost entirely of host origin but the osteocytes are of both host and donor origin. Conclusions The preliminary data presented in this manuscript demonstrates that chondrogenic priming of MSCs leads to bone formation in vivo using both human and rat cells. Furthermore, addition of β-glycerophosphate to the chondrogenic medium did not hamper this process. Using transgenic animals we also demonstrated that both host and donor cells played a role in bone formation. In conclusion these data indicate that in-vitro chondrogenic differentiation of human MSCs could lead to an alternative and superior approach for bone tissue engineering.

  17. The Consumer’s Opinions of the Food Service System: The 1973 Fort Lee Survey

    Science.gov (United States)

    1974-05-01

    Italian 0 08 Japanese 012 013 014 015 016 Polish (& Eastern Europe) Soul Southern Spanish (not Mexican) Other (please specifY------~ What...10 o 03 French o 11 0 04 General American Style 0 12 0 05 German 0 13 0 06 Greek 0 14 0 07 Italian 0 15 0 08 Japanese 0 16 Mexican New England...34Jzio"lc .!{!.* ~%*. 0% a. a. 6% 4% ’i’c: Less than ~% Table 5 Preferred Foods Cuisine General American Soul Southern English Italian

  18. Die opstel en evaluering van \\'n lees- en spelprogram vir Sesotho ...

    African Journals Online (AJOL)

    -speaking grade 1 learners, the value of a reading and spelling program for such learners is investigated. The research hypotheses postulates that the reading and spelling skills of Sesotho-speaking grade 1 learners that are exposed to a ...

  19. Lees' loss prevention in the process industries: hazard identification, assessment and control

    National Research Council Canada - National Science Library

    Mannan, Sam

    2012-01-01

    ... choose. As in the thronged and the lighted ways, so in the dark and the desert they stand, Wary and watchful all their days that their brethren's days may be long in the land.' Rudyard Kipling (The Sons of Martha, 1907) Wo einer kommt and saget an, Er hat es allen recht getan, So bitten wir diesen lieben Herrn, Er wo ¨ ll uns solche Kunste auch lehrn (...

  20. A critique of the Lees-Marshment market-oriented party model

    DEFF Research Database (Denmark)

    Ormrod, Robert P.

    2006-01-01

    between the related concepts of 'market orientation' and 'marketing orientation'. Empirical studies demonstrate problems with the model when applied to certain party types and electoral systems, the limitations on implementation of the model due to ideology and scarce resources, the partial application...

  1. 77 FR 60137 - Lee Metcalf National Wildlife Refuge, Ravalli County, MT; Final Comprehensive Conservation Plan...

    Science.gov (United States)

    2012-10-02

    ... management purpose, for migratory birds'' (Migratory Bird Conservation Act); and (2) ``for (a) incidental... migratory birds. Some wetland impoundments and U.S. Fish and Wildlife Service (nonpublic) roads would be removed or reduced in size to allow for river migration and to restore native gallery and riverfront...

  2. Operation Strong Wind (Fort Lee’s Response to a Local Tornado Disaster, 6 August 1993)

    Science.gov (United States)

    1993-11-01

    Interstate 95, and less than a mile from Old Towne and Pocahontas Island. Most destruction happened at Wal- Mart’s 110,000 square foot store which employed 400...area which was in the process of making a strong economic statement. Next to that area was an historic black community on Pocahontas Island in the... happen was Petersburg should have asked the governor that he request Federal troops. The governor in turn would have called the Federal Emergency

  3. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, Lee County, Alabama and Incorporated Areas

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  4. Global Marketing of Indigenous Culture: Discovering Native America with Lee Tiger and the Florida Miccosukee

    Science.gov (United States)

    Wiedman, Dennis

    2010-01-01

    Indigenous scholars such as Seminole/Shawnee historian, Donald Fixico, drew attention to the lack of academic literature about the proactive, planned, and strategic actions of indigenous peoples. Most histories portray indigenous peoples as responding, accommodating, and assimilating to non-Indians and the US government. This article highlights…

  5. Lee and Rhee et al., Afr J Tradit Complement Altern Med. (2016) 13 ...

    African Journals Online (AJOL)

    A preliminary or control paw withdrawal threshold was measured for each rat before drug injection. The cut-off value was determined as 30s in order to avoid tissue damage (Hargreaves et al., 1988). Chemical Test. The rats were housed in transparent plastic boxes with a floor made of 6mm wire mesh. After a 5-10min ...

  6. Meat Entree Item Production Guides Developed for Use in Ft. Lee Interim Central Food Preparation Facility

    Science.gov (United States)

    1975-03-01

    454 Col-Flo-67 Starch 0.70 Stock or water, cold 32.96 Pepper, black 0.01 Caramel coloring 0.01 Soup A gravy base, 0*56 beef 0.50 23.50...Type I, Class 1, 2 or 3 8. Flour, wheat, pastry - 7287-165-6898 FED-N-F-481, Type 1, Class B, Style 2 9. Food coloring, caramel - 8950-12940-782-2181...starch Stock or cold water Pepper, black Caramel coloring Soup ft gravy base, beef flavored 1.75 0.50 227 87.65 25.00 11350 0.04 0.01 5 O.O’l

  7. Aerial Photography and Imagery, Ortho-Corrected - 2007 Digital Orthophotos - FDEM - Lee County

    Data.gov (United States)

    NSGIC Education | GIS Inventory — This data set is one component of the Florida Division of Emergency Management's (FDEM) Project Management and Technical Services for Mapping within Coastal Florida...

  8. "Communication English" aan tegniese kolleges : 'n evaluering in die lig van lees- en spelvaardighede

    OpenAIRE

    2015-01-01

    M.Ed. The purpose of this study is primarily to evaluate the curriculum of the subject Communication English with specific reference to the component of reading and spelling. The rationale is to determine whether or not the reading and spelling skills of college students comply with the requirements of the private sector and, if found to be inadequate, appropriate recommendations would be made. The detrimental effect of reading and spelling problems on a person's entire being and self-actu...

  9. Lee and Park., Afr J Tradit Complement Altern Med. (2016) 13(2):72 ...

    African Journals Online (AJOL)

    Inflammation, the process aimed at restoring homeostasis after an insult, can be more damaging than the insult itself if uncontrolled, excessive, or prolonged ... Cells of the innate immune system detect pathogen-associated molecular patterns or endogenous molecules released as a result of tissue injury or inflammation ...

  10. Järvalaste Seltsi taassünd / Ants Kraut, Elle Lees

    Index Scriptorium Estoniae

    Kraut, Ants, 1955-

    2011-01-01

    7. juunil 2010 tähistati järvalaste ühendamise eestvõitleja Vaike Kotkase 90 juubelit. 4. detsembril 2010 toimus pidulik üldkoosolek, kus Tallinna Järvalaste Muinsuskaitse Selts otsustas jätkata ajaloolise nime Tallinna Järvalaste Selts all, tegutsedes Eesti Muinsuskaitse Seltsi allüksusena

  11. 77 FR 18852 - Lee Metcalf National Wildlife Refuge, Stevensville, MT; Draft Comprehensive Conservation Plan and...

    Science.gov (United States)

    2012-03-28

    ... visitors a consistent message about the purposes and values of the refuge and the mission of the Refuge... technicians (one full time and one career seasonal), and a visitor services specialist who would serve as a... Availability of Comments Before including your address, phone number, email address, or other personal...

  12. Spike Lee, Short Films and Social Issues in the English Classroom.

    Science.gov (United States)

    Kelly, Ernece B.

    In the past few years many movies have addressed social issues such as AIDS, parental estrangement, aging, battered women and children, and racism. Teachers of teenagers can capitalize on these kinds of serious films in two ways: by assuming that students have thought about some serious issues and by building on that assumption. Three movies of…

  13. Only three personality factors are fully replicable across languages: Reply to Ashton and Lee

    Czech Academy of Sciences Publication Activity Database

    De Raad, B.; Barelds, D.P.H.; Mlacić, B.; Church, A.T.; Katigbak, M. S.; Ostendorf, F.; Hřebíčková, Martina; Di Bias, L.; Szirmak, S.

    2010-01-01

    Roč. 44, č. 4 (2010), s. 442-445 ISSN 0092-6566 R&D Projects: GA ČR GAP407/10/2394 Institutional research plan: CEZ:AV0Z70250504 Keywords : lexical approach * factor replicability * cross-cultural * three factor s Subject RIV: AN - Psychology Impact factor : 1.756, year: 2010

  14. Fungal and enzymatic remediation of a wine lees and five wine-related distillery wastewaters

    CSIR Research Space (South Africa)

    Strong, PJ

    2008-09-01

    Full Text Available independently to determine its role in phenolic compounds degradation and colour change. The fungal treatment resulted in decreases in the wastewater chemical oxygen demand of up to 83 ± 2.1%, phenolic compounds of 87 ± 1.6% and colour of 88 ± 4.7%. Although...

  15. Arhitektuuriline vahendamine: kliima vs kultuur = Architectural mediations: climate vs culture / Franklin Lee, Anne Save de Beaurecueil

    Index Scriptorium Estoniae

    Lee, Franklin

    2011-01-01

    Tegelemisest Architectural Associationi 2. diplomistuudios ja büroos SUBdV keskkondlike ja kultuuriliste mõjurite duaalsusega arhitektuuris. Teemat on uuritud kolmes valdkonnas: sile vs artikuleeritud, keskkond vs ornament, kõrgtehnoloogia vs madaltehnoloogia. Architectural Association'i ja Hollandi Arhitektuuriinstituudi töötoast São Paulos 2010. a. suvel

  16. Een teks – meerdere betekenisse: Hoe lees ons die Bybel? | van ...

    African Journals Online (AJOL)

    One text – multiple meanings: How do we read the. Bible? This article discusses three ways of reading the Bible that are evident in the current theological debate in South Africa: a fundamentalist, foundationalist and critical reading. A brief description and evaluation of the three reading strategies are given. It is indicated that ...

  17. Tanith Lee's "Wolfland" and Suzy McKee Charnas's "Boobs" - Modern Tales of Magic

    OpenAIRE

    VILJANEN, EEVA

    2005-01-01

    Hakutermit: feministinen satu, Punahilkka, ihmissusi, fantasia, gotiikka, groteski Tämän pro gradu ­tutkielman tavoitteena on tarkastella kahta novellia, Tanith Leen ”Wolfland” ja Suzy McKee Charnasin ”Boobs”(Leena Peltosen suomennos ”Tissit” 1990) feministisen sadunkirjoitusperinteen näkökulmasta. Pyrin analysoimaan kirjailijoiden tapaa käyttää fantasian, gotiikan ja groteskin kuvastoa merkityksiä luodessaan. ”Wolfland” perustuu Perault’n ja Grimmin veljesten klassiseen satuun P...

  18. n resepsieteoretiese benadering tot die lees van Romeine 7:7—25

    African Journals Online (AJOL)

    between Augustine and Pelagius, leading up to the differences between exegetes and sistematic theologians in our ...... leerlinge is gevra om in volgorde elke teken (dit wil sê elke letter en punktuasieteken) in die eerste ses tot ... Pelagius verset het en in watter intense stryd hulle gewikkel was (vgl. Schulze 1978: 13—141).

  19. Mira y lee: Libro de actividades, 1 (Look and Read: Workbook 1).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This workbook, designed to be used with the textbook of the same title (FL 004 271), contains exercises, riddles, puzzles, coloring activities, and reinforcement of various word-perception skills and sentences. Included is a step-by-step procedure of phonetic analysis. The intention of the workbook is to enable students to increase their ability…

  20. Mira y lee: Libro de lectura 1, nivel 1 (Look and Read: Reader 1, Level 1).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This reading textbook contains a series of stories designed to relate to the natural interest of the school child. Students learn about a Puerto Rican family living in New York. New vocabulary is introduced gradually for the student to memorize. Included are exercises in oral expression and comprehension, auditory discrimination, intonation,…

  1. Lee y trabaja: Libro de lectura 2, nivel 1 (Read and Work: Reader 2, Level 1).

    Science.gov (United States)

    Martinez, Emiliano; and Others

    This reading textbook, the second of a series, is an anthology of stories designed to relate to the natural interest of the elementary school child. On this level the number of words to memorize is increased (on the average, four per unit) while at the same time, the study of word variants is introduced to begin analysis exercises based on the…

  2. Lee y trabaja: Libro de actividades, 2 (Read and Work: Workbook 2).

    Science.gov (United States)

    Martinez, Emiliano; And Others

    This workbook, designed to be used with the textbook of the same title (FL 004 272), contains exercises, riddles, puzzles, coloring activities, and reinforcement of various word-perception skills and sentences. Included is a step-by-step procedure of phonetic analysis. The intention of the workbook is to enable students to increase their ability…

  3. 75 FR 28643 - Pine Island, Matlacha Pass, Island Bay, and Caloosahatchee National Wildlife Refuges, Lee and...

    Science.gov (United States)

    2010-05-21

    ..., including fishing, canoeing, kayaking, motor boating, parasailing, windsurfing, ski tubing, using personal... wildlife and habitat values and would pursue completion of the approved acquisition boundaries from willing... and importance of these refuges in the landscape, and the importance of minimizing the impacts of...

  4. Alleviation of UV-B stress in Arabidopsis using tea catechins | Lee ...

    African Journals Online (AJOL)

    Ultraviolet-B (UV-B) has been confirmed to be harmful to living organisms and it is of concern that the amount of UV-B radiation reaching the earth's surface is increasing because of the depletion of the stratospheric ozone layer. Effect of different levels of tea catechins on morphological damage and expression of chalcone ...

  5. 75 FR 27576 - J.N. “Ding” Darling National Wildlife Refuge, Lee County, FL

    Science.gov (United States)

    2010-05-17

    ... threats to rare, threatened, and endangered species; (7) insufficient baseline wildlife and habitat data and lack of a comprehensive habitat management plan; and (8) insufficient resources to address refuge... changes. We would evaluate the need for and ability to provide parking at the Shell Mound Trail to address...

  6. Audrey Tautouga Coco jälgedes / Audrey Tautou ; intervjueerinud Lee Hanael

    Index Scriptorium Estoniae

    Tautou, Audrey, 1976-

    2009-01-01

    Näitlejanna mängib peaosa äsja esilinastunud eluloofilmis "Coco enne Chaneli" ("Coco avant Chanel", režissöör Anne Fontaine, Prantsusmaa 2009) ja on Chaneli moemaja parfüümi Chanel №5 reklaaminägu

  7. 76 FR 16636 - Pine Island, Matlacha Pass, Island Bay, and Caloosahatchee NWRs, Lee County, FL; Final...

    Science.gov (United States)

    2011-03-24

    ...)) requirements. We completed a thorough analysis of impacts on the human environment, which we included in the... toward the mission of the National Wildlife Refuge System, consistent with sound principles of fish and... will coordinate with the partners to address concerns related to the impacts from water quality...

  8. Aerial Photography and Imagery, Ortho-Corrected - 2010 NAIP Imagery - Lee County

    Data.gov (United States)

    NSGIC Education | GIS Inventory — This data set contains polygons delineating the seams boundary between acquired imagery used in the creation of DOQQs and compressed county mosaic (CCM). The DOQQ...

  9. Aerial Photography and Imagery, Ortho-Corrected - 2011 Digital Orthophotos - Lee County

    Data.gov (United States)

    NSGIC Education | GIS Inventory — The dataset consists of tiled orthogonal imagery produced from nadir images captured by Pictometry International January 2nd and March 21st, 2011. Automatic aerial...

  10. Lee and Park., Afr J Tradit Complement Altern Med. (2016) 13(2):72 ...

    African Journals Online (AJOL)

    binding with the complex CD14, myeloid differentiation protein 2, and Toll-like receptor 4 (Paciello et al., 2013). .... colony-stimulating factor (GM-CSF), leukemia inhibitory factor (LIF; IL-6 class cytokine), lipopolysaccharide-induced CXC ...... The actual effect of CCH in acute and chronic inflammatory diseases deserves.

  11. Shelf currents, lee-trapped and transient eddies on the inshore ...

    African Journals Online (AJOL)

    An ADCP mooring at a depth of 32 m off Port Alfred indicated that the countercurrent typically lasted a few days, but at times remained in the same direction for as long as 10 days. Velocities ranged between 20 and 60 cm s–1 with maximum values of ~80 cm s–1. The S–ADCP data also highlighted the existence of cyclonic ...

  12. Tsüklist "Spoon Riveri koolnud" : [luuletused] / Edgar Lee Masters ; tõlk. Boris Kabur

    Index Scriptorium Estoniae

    Masters, Edgar Lee

    2008-01-01

    Sisu: Poeet Theodore ; Lucinda Matlock ; Willard Fluke ; Diakon Taylor ; Viiuldaja Jones ; Dora Williams ; John M. Church ; Vene Sonja ; Petit, poeet ; Pastor Abner Peet ; Yee Bow ; Roger Heston ; Carl Hamblin ; Hortense Robbins ; Tom Merritt ; Proua Merritt ; Elmer Karr ; Anne Rutledge ; Marie Bateson ; Scholfield Huxley ; Willie Metcalf. Elu- ja loomeloolisi andmeid autori kohta lk. 519-520

  13. Only three personality factors are fully replicable across languages: Reply to Ashton and Lee

    Czech Academy of Sciences Publication Activity Database

    De Raad, B.; Barelds, D.P.H.; Mlacić, B.; Church, A.T.; Katigbak, M. S.; Ostendorf, F.; Hřebíčková, Martina; Di Bias, L.; Szirmak, S.

    2010-01-01

    Roč. 44, č. 4 (2010), s. 442-445 ISSN 0092-6566 R&D Projects: GA ČR GAP407/10/2394 Institutional research plan: CEZ:AV0Z70250504 Keywords : lexical approach * factor replicability * cross - cultural * three factors Subject RIV: AN - Psychology Impact factor: 1.756, year: 2010

  14. Edwards: kommunismi ajalugu on vaja tunda, et see ei korduks / Lee Edwards

    Index Scriptorium Estoniae

    Edwards, Lee

    2011-01-01

    Intervjuu Washingtonis asuva kommunismiohvrite mälestusmärgi rajamise fondi esimehe USA konservatiivse mõttekoja Heritage Foundation liikmega kommunismi olemusest ja ajaloost ning selle selgitamise vajadusest

  15. Järvamaa : Äripäev maakonnas / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2007-01-01

    Järvamaa ettevõtete TOP. Vt. samas: Mäo tehnoküla paneb Eestimaa südame tuksuma. Diagramm; Järva gasellid üle Eesti ilma ei tee; Käsitöö annab Vikingile konkurentsieelise; Paide MEK toodab metallkonstruktsioone; Ülemaailmne turg tagab kasvuvõimaluse; Mäo tehnopargil piire pole. Küsimustele vastab Toomas Agasild

  16. Bruce Lee vs. Fu Manchu: Kung Fu Films and Asian American Stereotypes in America.

    Science.gov (United States)

    Farquhar, Judith; Doi, Mary L.

    1978-01-01

    Discussed in this article are numerous films which feature Asian characters and the influence these films have on stereotyped images of Asians and prevailing racist attitudes toward Asian Americans. (EB)

  17. Evaluation of Learning Strategies Training Program 94B10 Fort Lee, Virginia.

    Science.gov (United States)

    1981-11-30

    28 perform during evaluation; and 3) differences between Cycle 1 and Cycle 2 experimental group student performance casts doubt on whether superiority...Creamy, cheesy, macaroni flavor (not bland, dry, or sticky) - Season to taste (not flat or overpowering) - Sauce castes smooth (not lumpy or floury...takte* * . ** .....1/4 x rawA (13 o ladle ) egg 4.1 :..Id talIp4j9fr4$tu gUluut On je ~ ouem I 4qol4ea brown. ~Q I$T 5 M peeusay, gently g99~I94 u ith wit

  18. The Anatomy of the Solemn in Ezenduka's “Lee Nnukwu Ukochukwu”

    African Journals Online (AJOL)

    Among Igbo liturgical music composers of the last fifty years, Ezenduka has stood tall like a mountain peak in a range of many mountains. The popularity of his compositions has provoked unusual interest among sacred musicologists and ethnomusicologists. The search for the basic and unique elements of his ...

  19. Brassia campestris L. ssp. chinensis L.var. utilis Tsen et Lee

    African Journals Online (AJOL)

    omodibo

    2012-12-31

    Dec 31, 2012 ... Soft Rot Disease Caused by Pectobacterium carotovorum subsp. carotovorum of Chinese Cabbage Followed by Climate Change in. Highlands of Korea. Society for plant pathology in China Annual. Academic Symposium, Chinese agricultural science and Technology. Press, Yichang, Hubei, China.

  20. Impact of Parameterized Lee Wave Drag on the Energy Budget of an Eddying Global Ocean Model

    Science.gov (United States)

    2013-08-26

    of Mexico and other regions in Fig. 2b of Arbic et al. (2010) relative to their Fig. 2a. In subsequent versions of HY- COM simulations with embedded...use of the leap- frog time-stepping scheme (Griffies et al., 2000), it is an unmeasured source of dissi- pation. An associated imbalance in surface...Molines, J.-M., New , A.L., 2001. Circulation characteristics in three eddy- permitting models of the North Atlantic. Progr. Oceanogr. 48, 123–161