WorldWideScience

Sample records for learned zheadquarters 26th

  1. The 26th Amendment and Youth Voting Rights.

    Science.gov (United States)

    Schamel, Wynell

    1996-01-01

    Describes learning activities to be used in conjunction with a facsimile of the 92nd Congress's joint resolution passing the 26th Amendment extending the voting franchise to 18-year-olds. These activities include document analysis, time lines, class discussions, and storytelling. Briefly reviews the amendment process. (MJP)

  2. Aftershocks of 26th January 2001 Bhuj earthquake and ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Aftershocks of 26th January 2001 Bhuj earthquake and seismotectonics of the Kutch region. K S Misra∗, R Bhutani and R Sonp. Geological Survey of India, Alandi Road, Pune - 6, India. ∗email: gsi−pune@vsnl.com. The 26th January 2001 Bhuj earthquake was followed by intense aftershock activity. Aftershock data from ...

  3. Aftershock activity of Bhuj earthquake of January 26th, 2001

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    2001-01-26

    Jan 26, 2001 ... The epicenter of the mainshock falls on the southern edge of ... Daily frequency of aftershocks (ML ≥ 1) from February 5th to February 27th, 2001. local network around the .... Financial support to carry out the study became.

  4. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA) (12th, Maynooth, Greater Dublin, Ireland, October 24-26, 2015)

    Science.gov (United States)

    Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaias, Pedro, Ed.

    2015-01-01

    These proceedings contain the papers of the 12th International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2015), October 24-26, 2015, which has been organized by the International Association for Development of the Information Society (IADIS), co-organized by Maynooth University, Ireland, and endorsed by the…

  5. CALL in a Climate of Change: Adapting to Turbulent Global Conditions. Short Papers from EUROCALL 2017 (25th, Southampton, United Kingdom, August 23-26, 2017)

    Science.gov (United States)

    Borthwick, Kate, Ed.; Bradley, Linda, Ed.; Thouësny, Sylvie, Ed.

    2017-01-01

    The 25th European Association of Computer-Assisted Language Learning (EUROCALL) conference was hosted by Modern Languages and Linguistics at the University of Southampton, in the United Kingdom, from the 23rd to the 26th of August 2017. The theme of the conference was "CALL in a climate of change." The theme encompassed the notion of how…

  6. Introduction to the Highlights of the 26th ASIC Conference.

    Science.gov (United States)

    Nehlig, Astrid

    2017-09-10

    The 26th ASIC Conference that was held in 2016 in Kunming, China has been marking the 50th anniversary of the creation of ASIC. The meeting in China was well attended by over 400 participants from all over the world and allowed fruitful exchanges among participants from all horizons of coffee science.

  7. TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

    KAUST Repository

    Meller, Stephan

    2015-07-13

    Interleukin 17-producing helper T cells (TH 17 cells) have a major role in protection against infections and in mediating autoimmune diseases, yet the mechanisms involved are incompletely understood. We found that interleukin 26 (IL-26), a human TH17 cell-derived cytokine, is a cationic amphipathic protein that kills extracellular bacteria via membrane-pore formation. Furthermore, TH17 cell-derived IL-26 formed complexes with bacterial DNA and self-DNA released by dying bacteria and host cells. The resulting IL-26-DNA complexes triggered the production of type I interferon by plasmacytoid dendritic cells via activation of Toll-like receptor 9, but independently of the IL-26 receptor. These findings provide insights into the potent antimicrobial and proinflammatory function of TH17 cells by showing that IL-26 is a natural human antimicrobial that promotes immune sensing of bacterial and host cell death. © 2015 Nature America, Inc.

  8. TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

    KAUST Repository

    Meller, Stephan; Di Domizio, Jeremy; Voo, Kui S; Friedrich, Heike C; Chamilos, Georgios; Ganguly, Dipyaman; Conrad, Curdin; Gregorio, Josh; Le Roy, Didier; Roger, Thierry; Ladbury, John E; Homey, Bernhard; Watowich, Stanley; Modlin, Robert L; Kontoyiannis, Dimitrios P; Liu, Yong-Jun; Arold, Stefan T.; Gilliet, Michel

    2015-01-01

    Interleukin 17-producing helper T cells (TH 17 cells) have a major role in protection against infections and in mediating autoimmune diseases, yet the mechanisms involved are incompletely understood. We found that interleukin 26 (IL-26), a human TH17 cell-derived cytokine, is a cationic amphipathic protein that kills extracellular bacteria via membrane-pore formation. Furthermore, TH17 cell-derived IL-26 formed complexes with bacterial DNA and self-DNA released by dying bacteria and host cells. The resulting IL-26-DNA complexes triggered the production of type I interferon by plasmacytoid dendritic cells via activation of Toll-like receptor 9, but independently of the IL-26 receptor. These findings provide insights into the potent antimicrobial and proinflammatory function of TH17 cells by showing that IL-26 is a natural human antimicrobial that promotes immune sensing of bacterial and host cell death. © 2015 Nature America, Inc.

  9. 26th Annual ESNA/IUR Meeting: Soil-Plant Relationships

    International Nuclear Information System (INIS)

    Gerzabek, M. H.

    1996-11-01

    The radioecological session of the 26 th annual meeting of ESNA (in Busteni/Romania) is for INIS interesting. The session was a joint session with the soil-to-plant transfer working group of the IUR. (Botek)

  10. 26th Conference of Spacecraft TT&C Technology in China

    CERN Document Server

    Qian, Weiping

    2013-01-01

    Proceedings of the 26th Conference of Spacecraft TT&C Technology in China collects selected papers from the 26th Conference of Spacecraft TT&C Technology in China held in Nanjing on October 16-19, 2012. The book features state-of-the-art studies on spacecraft TT&C in China with the theme of “Shared and Flexible TT&C Systems”. The selected works can help  promote development of spacecraft TT&C technology towards interconnectivity, resource sharing, flexibility and high efficiency. Researchers and engineers in the field of aerospace engineering and communication engineering can benefit from the book. Rongjun Shen is the Academician of Chinese Academy of Engineering; Weiping Qian is the Director General of Beijing Institute of Tracking and Telecommunications Technology.

  11. 26{sup th} Annual ESNA/IUR Meeting: Soil-Plant Relationships

    Energy Technology Data Exchange (ETDEWEB)

    Gerzabek, M H [ed.; Oesterreichisches Forschungszentrum Seibersdorf, 2444 Seibersdorf (Austria)

    1996-11-01

    The radioecological session of the 26{sup th} annual meeting of ESNA (in Busteni/Romania) is for INIS interesting. The session was a joint session with the soil-to-plant transfer working group of the IUR. (Botek)

  12. 26th European Congress of Arachnology in Midreshet Ben-Gurion

    OpenAIRE

    Schaider, Miriam

    2011-01-01

    Early in September, 130 arachnologists and 11 accompanying persons from 27 countries from all over the world headed to Israel to attend the 26th European Congress of Arachnology hosted by the Jacob Blaustein Institutes for Desert Research.

  13. Example of answers to problems of the 26th and 27th examination for the chief technician of nuclear fuel-2

    Energy Technology Data Exchange (ETDEWEB)

    Sakuta, Takashi; Minato, Kazuo; Morita, Yasuji; Nishiza, Masahiro; Akatsu, Eiko [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1995-10-01

    This is an example of the answers to the 26th and 27th examination problems for certification of the chief technician of nuclear fuel. Short explanations or references are given for each answer. (author).

  14. Example of answers to problems of the 26th and 27th examination for the chief technician of nuclear fuel-2

    International Nuclear Information System (INIS)

    Sakuta, Takashi; Minato, Kazuo; Morita, Yasuji; Nishiza, Masahiro; Akatsu, Eiko

    1995-10-01

    This is an example of the answers to the 26th and 27th examination problems for certification of the chief technician of nuclear fuel. Short explanations or references are given for each answer. (author)

  15. PREFACE: 26th Symposium on Plasma Science for Materials (SPSM-26)

    Science.gov (United States)

    2014-06-01

    26th Symposium on Plasma Science for Materials (SPSM-26) Takayuki Watanabe The 26th Symposium on Plasma Science for Materials (SPSM-26) was held in Fukuoka, Japan on September 23-24, 2013. SPSM has been held annually since 1988 under the sponsorship of The 153rd Committee on Plasma Materials Science, Japan Society for the Promotion of Science (JSPS). This symposium is one of the major activities of the Committee, which is organized by researchers in academia and industry for the purpose of advancing intersectional scientific information exchange and discussion of science and technology of plasma materials processing. Plasma processing have attracted extensive attention due to their unique advantages, and it is expected to be utilized for a number of innovative industrial applications such as synthesis of high-quality and high-performance nanomaterials. The advantages of plasmas including high chemical reactivity in accordance with required chemical reactions are beneficial for innovative processing. In recent years, plasma materials processing with reactive plasmas has been extensively employed in the fields of environmental issues and biotechnology. This conference seeks to bring different scientific communities together to create a forum for discussing the latest developments and issues. The conference provides a platform for the exploration of both fundamental topics and new applications of plasmas by the contacts between science, technology, and industry. The conference was organized in plenary lectures, invited, contributed oral presentations, and poster sessions. At this meeting, we had 142 participants from 10 countries and 104 presentations, including 11 invited presentations. This year, we arranged special topical sessions that cover Plasma Medicine and Biotechnologies, Business and Academia Cooperation, Plasma with Liquids, Plasma Processes for Nanomaterials, together with Basic, Electronics, and Thermal Plasma sessions. This special issue presents 28

  16. Adult Learning Development in Poland in the 20th Century

    Science.gov (United States)

    Boiarska-Khomenko, Anna

    2017-01-01

    The article presents a retrospective analysis of adult learning development in Poland in the 20th century. Based on the study and analysis of historical and pedagogical literature, normative documents of the official bodies of Polish government, the periodical press of the 20th century, several stages of adult learning development, in the…

  17. Conference report on Media and Learning Conference, Brussels, March 9th & 10th, 2016

    NARCIS (Netherlands)

    Zac Woolfitt

    2016-01-01

    On March 9th and 10th Zac Woolfitt attended the Media and Learning Conference in Brussels. The programme of this annual conference examines ‘developments, services and uses of media in education and training to […] identify policies and initiatives that promote digital and media competence at all

  18. Liquid-liquid extraction of Th4+ and UO22+ by LIX-26 and its mixtures

    International Nuclear Information System (INIS)

    Singh, S.; Panda, C.R.; Chakravortty, V.; Dash, K.C.

    1988-01-01

    Solvent extractions of thorium(IV) and uranium(VI) by a commercially available chelating extractant LIX-26 (an alkylated 8-hydroxyquinoline) of 8-hydroxyquinoline, benzoic or salicylic acid, dipentyl sulfoxide (DPSO) and their mixtures with butanol as modifier in benzene/methylisobutyl ketone (MIBK) as a diluent were studied. The influence of concentration of various anions on the extraction of Th 4+ by mixtures of LIX-26 and benzoic acid was studied. Studies on extraction of thorium(IV) and uranium(VI) by mixtures of LIX-26 (HQ) and DPSO show that the extracted species are possibly of the type [(ThQ 2 (DPSO) 2 (SCN) 2 )] and [(UO 2 Q 2 (DPSO)]), respectively. (author) 22 refs.; 8 figs

  19. Proceedings of the 26th annual meeting of the National Council on Radiation Protection Measurements

    International Nuclear Information System (INIS)

    Richmond, C.R.

    1991-01-01

    This book reports on the 26th Annual Meeting of the National Council on Radiation Protection and Measurements which addressed the topic Health and Ecological Implications of Radioactively Contaminated Environments, a topic of great current interest and importance. The meeting was divided into five subtopics. The first dealt with the contaminated sites themselves, the second with human health implications, the third on remediation, the fourth (a panel) on lessons learned and issues of the future and finally a summation. The meeting also included progress reports on the work of three NCRP committees, Scientific Committee 1-2 on the Assessment of Risk for Radiation Protection Purposes, Scientific Committee 66 on Biological Effects and Exposure Criteria for Ultrasound and Scientific Committee 83 on Identification of Research Needs for Radiation Protection. Summaries of these reports prepared by their respective chairmen are included in this volume

  20. Computer and Information Sciences II : 26th International Symposium on Computer and Information Sciences

    CERN Document Server

    Lent, Ricardo; Sakellari, Georgia

    2012-01-01

    Information technology is the enabling foundation for all of human activity at the beginning of the 21st century, and advances in this area are crucial to all of us. These advances are taking place all over the world and can only be followed and perceived when researchers from all over the world assemble, and exchange their ideas in conferences such as the one presented in this proceedings volume regarding the 26th International Symposium on Computer and Information Systems, held at the Royal Society in London on 26th to 28th September 2011. Computer and Information Sciences II contains novel advances in the state of the art covering applied research in electrical and computer engineering and computer science, across the broad area of information technology. It provides access to the main innovative activities in research across the world, and points to the results obtained recently by some of the most active teams in both Europe and Asia.

  1. 26th Solvay Conference on Physics

    CERN Document Server

    Gross, David; Sevrin, Alexander; Astrophysics and Cosmology

    2016-01-01

    Ever since 1911, the Solvay Conferences have shaped modern physics. The format is quite different from other conferences as the emphasis is placed on discussion. The 26th edition held in October 2014 in Brussels and chaired by Roger Blandford continued this tradition and addressed some of the most pressing open questions in the fields of astrophysics and cosmology, gathering many of the leading figures working on a wide variety of profound problems.The proceedings contain the 'rapporteur talks' giving a broad overview with unique insights by distinguished renowned scientists. These lectures cover the five sessions: 'Neutron Stars', 'Black Holes', 'Cosmic Dawn', 'Dark Matter' and 'Cosmic Microwave Background'.In the Solvay tradition, the proceedings also include the prepared comments to the rapporteur talks. The discussions among the participants — expert, yet lively and sometimes contentious — have been edited to retain to retain their flavor and are reproduced in full. The reader is taken on a breathtaki...

  2. Proceedings of the Combined 20th International Workshop on Expressiveness in Concurrency and 10th Workshop on Structural Operational Semantics (EXPRESS/SOS 2013, Buenos Aires, Argentina, August 26, 2013)

    NARCIS (Netherlands)

    Borgström, J.; Luttik, B.

    2013-01-01

    This volume contains the proceedings of the Combined 20th International Workshop on Expressiveness in Concurrency and the 10th Workshop on Structural Operational Semantics (EXPRESS/SOS 2013) which was held on 26th August, 2013 in Buenos Aires, Argentina, as an affiliated workshop of CONCUR 2013, the

  3. The 26th International Nuclear Physics Conference

    Science.gov (United States)

    It was a pleasure to welcome all delegates and accompanying persons to Adelaide for the 26th International Conference in Nuclear Physics, INPC2016. As the major meeting in our field, it was a wonderful opportunity to catch up with colleagues from around the world, learn about the very latest developments and share ideas. We were grateful for the support of the Commission on Nuclear Physics, C12, of the International Union of Pure and Applied Physics (IUPAP), which chose Adelaide to host this meeting. We were also honoured that the President of IUPAP, Prof. Bruce McKellar was present at the meeting to welcome delegates and participate in the proceedings. We acknowledge the financial support for the conference which was made available by a number of organisations. We were especially grateful to the major sponsors, the Adelaide Convention Bureau, the University of Adelaide, the Australian National University and ANSTO, as well as IUPAP, the ARC Centre of Excellence for Particle Physics at the Terascale (CoEPP) and several of the world's major nuclear physics laboratories, BNL, GSI, JLab and TRIUMF. As a result of these contributions we were able to offer support to attend the conference to more than 50 international students. Not only did we have a superb scientific program but, consistent with IUPAP guidelines, more than 40% of the invited plenary talks were presented by women. In order to reach out to the local community, Cynthia Keppel (from JLab) presented a public lecture on Hadron Beam Therapy on Tuesday evening, September 13th. As presenting a talk is now often a condition for financial support to attend an international conference, there were 11 simultaneous parallel sessions with more than 350 presentations. We are especially grateful to the International Advisory Committee, the Program Committee and the Conveners whose advice and hard work made it possible for all this to come together. I would also like to acknowledge the work of the Local Organising

  4. FOREWORD: 26th IAHR Symposium on Hydraulic Machinery and Systems

    Science.gov (United States)

    Wu, Yulin; Wang, Zhengwei; Liu, Shuhong; Yuan, Shouqi; Luo, Xingqi; Wang, Fujun

    2012-11-01

    The 26th IAHR Symposium on Hydraulic Machinery and Systems, will be held in Beijing, China, 19-23 August 2012. It is jointly organized by Tsinghua University, State Key Laboratory of Hydro Science and Hydraulic Engineering, China, Jiangsu University, Xi'an University of Technology, China Agricultural University, National Engineering Research Center of Hydropower Equipment and Dongfang Electric Machinery Co., Ltd. It is the second time that China hosts such a symposium. By the end of 2011, the China electrical power system had a total of 1 050 GW installed power, out of which 220 GW was in hydropower plants. The energy produced in hydropower facilities was 662.6 TWh from a total of 4,720 TWh electrical energy production in 2011. Moreover, in 2020, new hydropower capacities are going to be developed, with a total of 180 GW installed power and an estimated 708 TWh/year energy production. And in 2011, the installed power of pumped storage stations was about 25GW. In 2020, the data will be 70GW. At the same time, the number of pumps used in China is increasing rapidly. China produces about 29,000,000 pumps with more than 220 series per year. By the end of 2011, the Chinese pumping system has a total of 950 GW installed power. The energy consumed in pumping facilities was 530 TWh in 2011. The pump energy consumption accounted for about 12% of the national electrical energy production. Therefore, there is a large market in the field of hydraulic machinery including water turbines, pump turbines and a variety of pumps in China. There are also many research projects in this field. For example, we have conducted National Key Research Projects on 1000 MW hydraulic turbine, and on the pump turbines with high head, as well as on the large capacity pumps for water supply. Tsinghua University of Beijing is proud to host the 26th IAHR Symposium on Hydraulic Machinery and Systems. Tsinghua University was established in 1911, after the founding of the People's Republic of China. It

  5. 117th Annual Meeting, Medical Library Association, Inc., Seattle, WA, May 26–31, 2017

    Directory of Open Access Journals (Sweden)

    Nicole Mitchell

    2018-01-01

    Full Text Available The Medical Library Association (MLA held its 117th annual meeting in Seattle, Washington, May 26–31, 2017, at the Washington State Convention Center. The meeting theme was “Dream, Dare, Do.”

  6. Abstracts of the “26th Hungarian Conference on Rabbit Production”

    Directory of Open Access Journals (Sweden)

    26th Hungarian Conference on Rabbit Prod Kaposvár, Hungary, May 31, 2014

    2015-03-01

    Full Text Available About 100 participants attended the 26th Hungarian Conference on Rabbit Production at Kaposvár, organised by Kaposvár University, the Hungarian Branch of the WRSA and the Rabbit Production Board. This is the largest and most popular event for rabbit breeders in Hungary. Twenty papers were presented by senior and young scientists. Topics of the papers covered all fields of rabbit production (production, housing and welfare, reproduction, genetics, nutrition, meat quality. Full papers are available from the organiser (matics.zsolt@ke.hu on request.

  7. Communicating Science to Impact Learning? A Phenomenological Inquiry into 4th and 5th Graders' Perceptions of Science Information Sources

    Science.gov (United States)

    Gelmez Burakgazi, Sevinc; Yildirim, Ali; Weeth Feinstein, Noah

    2016-01-01

    Rooted in science education and science communication studies, this study examines 4th and 5th grade students' perceptions of science information sources (SIS) and their use in communicating science to students. It combines situated learning theory with uses and gratifications theory in a qualitative phenomenological analysis. Data were gathered…

  8. Proceedings of the 11th World Conference on Mobile and Contextual Learning

    OpenAIRE

    Specht, Marcus; Sharples, Mike; Multisilta, Jari

    2013-01-01

    Specht, M., Sharples, M., & Multisilta, J. (Eds.) (2012). Proceedings of the 11th World Conference on Mobile and Contextual Learning (mLearn 2012). October, 16-18, 2012, Helsinki, Finland. Published by CEUR Workshop Proceedings, 2012, Vol. 995. Retrieved from http://ceur-ws.org/Vol-955/

  9. 26 CFR 1.25A-4 - Lifetime Learning Credit.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Lifetime Learning Credit. 1.25A-4 Section 1.25A-4... Rates During A Taxable Year § 1.25A-4 Lifetime Learning Credit. (a) Amount of the credit—(1) Taxable years beginning before January 1, 2003. Subject to the phaseout of the education tax credit described in...

  10. The use of mobile learning by 6th-year medical students in a minimally-supported environment

    OpenAIRE

    Ken Masters; Zahra Al-Rawahi

    2012-01-01

    Objectives: The study aims to identify the impact of minimal support on medical students' mobile learning activities. Methods: The study was performed at the Sultan Qaboos University, Oman, on 129 medical students in their 7th year. The study consisted of a quantitative survey of the students, focussing on their mobile learning activities during their 6th year, while using their own mobile devices (such as smart phones) for mobile learning activities. In addition, their perceptions of barrier...

  11. 19th International Conference on Interactive Collaborative Learning

    CERN Document Server

    Guralnick, David; Uhomoibhi, James

    2017-01-01

    This book presents the proceedings of the 19th International Conference on Interactive Collaborative Learning, held 21-23 September 2016 at Clayton Hotel in Belfast, UK. We are currently witnessing a significant transformation in the development of education. The impact of globalisation on all areas of human life, the exponential acceleration of developments in both technology and the global markets, and the growing need for flexibility and agility are essential and challenging elements of this process that have to be addressed in general, but especially in the context of engineering education. To face these topical and very real challenges, higher education is called upon to find innovative responses. Since being founded in 1998, this conference has consistently been devoted to finding new approaches to learning, with a focus on collaborative learning. Today the ICL conferences have established themselves as a vital forum for the exchange of information on key trends and findings, and of practical lessons le...

  12. 6th International Conference in Methodologies and intelligent Systems for Technology Enhanced Learning

    CERN Document Server

    Prieta, Fernando; Mascio, Tania; Gennari, Rosella; Rodríguez, Javier; Vittorini, Pierpaolo

    2016-01-01

    The 6th International Conference in Methodologies and intelligent Systems for Technology Enhanced Learning held in Seville (Spain) is host by the University of Seville from 1st to 3rd June, 2016. The 6th edition of this conference expands the topics of the evidence-based TEL workshops series in order to provide an open forum for discussing intelligent systems for TEL, their roots in novel learning theories, empirical methodologies for their design or evaluation, stand-alone solutions or web-based ones. It intends to bring together researchers and developers from industry, the education field and the academic world to report on the latest scientific research, technical advances and methodologies.

  13. 76 FR 16419 - Filing Dates for the New York Special Election in the 26th Congressional District

    Science.gov (United States)

    2011-03-23

    ... 26th Congressional District AGENCY: Federal Election Commission. ACTION: Notice of filing dates for special election. SUMMARY: New York has scheduled a Special General Election on May 24, 2011, to fill the.... Committees required to file reports in connection with the Special General Election on May 24, 2011, shall...

  14. STUDY OF GEOGRAPHY TEXTBOOKS FOR 9th, 10th, 11th AND 12th GRADES. CASE STUDY: MAHARASHTRA STATE, INDIA

    Directory of Open Access Journals (Sweden)

    MARIANA-DOINA CÎINEANU

    2017-02-01

    Full Text Available The introduction conveys some data on learning in India and on designing Geography textbooks in this country. The present paper is reliant on four Geography textbooks, ranging from the 9th to the 12th grade. As regards each textbook, the study considers their learning units, then analyses their structure, the unitary way of designing them, the components of the panels of authors, the texts, illustrative materials, drills, learning activities, language, the wealth of Geography lexis, and the glossary.

  15. 26th International Workshop on Operator Theory and its Applications

    CERN Document Server

    Kaashoek, Marinus; Vasilevski, Nikolai; Vinnikov, Victor; IWOTA 2015; Operator theory in different settings and related applications

    2018-01-01

    This book provides a selection of reports and survey articles on the latest research in the area of single and multivariable operator theory and related fields. The latter include singular integral equations, ordinary and partial differential equations, complex analysis, numerical linear algebra, and real algebraic geometry – all of which were among the topics presented at the 26th International Workshop in Operator Theory and its Applications, held in Tbilisi, Georgia, in the summer of 2015. Moreover, the volume includes three special commemorative articles. One of them is dedicated to the memory of Leiba Rodman, another to Murray Marshall, and a third to Boris Khvedelidze, an outstanding Georgian mathematician and one of the founding fathers of the theory of singular integral equations. The book will be of interest to a broad range of mathematicians, from graduate students to researchers, whose primary interests lie in operator theory, complex analysis and applications, as well as specialists in mathemati...

  16. Human Brain Proteome Project - 12th HUPO BPP Workshop. 26 September 2009, Toronto, Canada.

    Science.gov (United States)

    Gröttrup, Bernd; Eisenacher, Martin; Stephan, Christian; Marcus, Katrin; Lee, Bonghee; Meyer, Helmut E; Park, Young Mok

    2010-06-01

    The HUPO Brain Proteome Project (HUPO BPP) held its 12th workshop in Toronto on 26 September 2009 prior to the HUPO VIII World Congress. The principal aim of this project is to obtain a better understanding of neurodiseases and ageing, with the ultimate objective of discovering prognostic and diagnostic biomarkers, in addition to the development of novel diagnostic techniques and new medications. The attendees came together to discuss progress in the human clinical neuroproteomics and to define the needs and guidelines required for more advanced proteomic approaches.

  17. The Development of Learning Model Based on Problem Solving to Construct High-Order Thinking Skill on the Learning Mathematics of 11th Grade in SMA/MA

    Science.gov (United States)

    Syahputra, Edi; Surya, Edy

    2017-01-01

    This paper is a summary study of team Postgraduate on 11th grade. The objective of this study is to develop a learning model based on problem solving which can construct high-order thinking on the learning mathematics in SMA/MA. The subject of dissemination consists of Students of 11th grade in SMA/MA in 3 kabupaten/kota in North Sumatera, namely:…

  18. Proceedings of the International Conference on Educational Data Mining (EDM) (8th, Madrid, Spain, June 26-29, 2015)

    Science.gov (United States)

    Santos, Olga Cristina, Ed.; Boticario, Jesus Gonzalez, Ed.; Romero, Cristobal, Ed.; Pechenizkiy, Mykola, Ed.; Merceron, Agathe, Ed.; Mitros, Piotr, Ed.; Luna, Jose Maria, Ed.; Mihaescu, Cristian, Ed.; Moreno, Pablo, Ed.; Hershkovitz, Arnon, Ed.; Ventura, Sebastian, Ed.; Desmarais, Michel, Ed.

    2015-01-01

    The 8th International Conference on Educational Data Mining (EDM 2015) is held under auspices of the International Educational Data Mining Society at UNED, the National University for Distance Education in Spain. The conference held in Madrid, Spain, July 26-29, 2015, follows the seven previous editions (London 2014, Memphis 2013, Chania 2012,…

  19. e-Portfolios for Learning and Development: without constant internet or electrical grid access

    NARCIS (Netherlands)

    Casey, John; Calverley, Gayle; Greller, Wolfgang; Uhomoibhi, James

    2011-01-01

    Casey, J., Calverley, G., Greller, W., & Uhomoibhi, J. (2010, 26-28 May). e-Portfolios for Learning and Development: without constant internet or electrical grid access. Presentation at the 5th International Conference on ICT for Development, Education, and Training - eLearning Africa, Lusaka,

  20. A confrontation with reality - Proceedings of the 19th Association for Learning Technology Conference

    NARCIS (Netherlands)

    Hawkridge, David; Verjans, Steven; Wilson, Gail

    2012-01-01

    Hawkridge, D., Verjans, S., & Wilson, G. (Eds.) (2012). A confrontation with reality - Proceedings of the 19th Association for Learning Technology Conference (ALT-C 2012). September, 11-14, 2012, Manchester, UK.

  1. Bridging the Gap, Facing the Challenge—the 26th Great Wall International Congress of Cardiology (GW-ICC)

    OpenAIRE

    Zhang, Yingmei; Ren, Jun

    2016-01-01

    The joint venue of the 26th Great Wall International Congress of Cardiology (GW-ICC) & Asia Pacific Heart Congress 2015 (APHC 2015) & International Congress Cardiovascular Prevention and Rehabilitation 2015 (ICCPR 2015) were held from October 29 to November 01, 2015 at the China National Convention Center (CNCC), Beijing, China. This year’s conference focused on cardiovascular disease prevention, health promotion, education and training, as well as disease management and rehabilitation.

  2. The quality and impact of computer supported collaborative learning (CSCL) in radiology case-based learning

    International Nuclear Information System (INIS)

    Kourdioukova, Elena V.; Verstraete, Koenraad L.; Valcke, Martin

    2011-01-01

    Objective: The aim of this research was to explore (1) clinical years students' perceptions about radiology case-based learning within a computer supported collaborative learning (CSCL) setting, (2) an analysis of the collaborative learning process, and (3) the learning impact of collaborative work on the radiology cases. Methods: The first part of this study focuses on a more detailed analysis of a survey study about CSCL based case-based learning, set up in the context of a broader radiology curriculum innovation. The second part centers on a qualitative and quantitative analysis of 52 online collaborative learning discussions from 5th year and nearly graduating medical students. The collaborative work was based on 26 radiology cases regarding musculoskeletal radiology. Results: The analysis of perceptions about collaborative learning on radiology cases reflects a rather neutral attitude that also does not differ significantly in students of different grade levels. Less advanced students are more positive about CSCL as compared to last year students. Outcome evaluation shows a significantly higher level of accuracy in identification of radiology key structures and in radiology diagnosis as well as in linking the radiological signs with available clinical information in nearly graduated students. No significant differences between different grade levels were found in accuracy of using medical terminology. Conclusion: Students appreciate computer supported collaborative learning settings when tackling radiology case-based learning. Scripted computer supported collaborative learning groups proved to be useful for both 5th and 7th year students in view of developing components of their radiology diagnostic approaches.

  3. The quality and impact of computer supported collaborative learning (CSCL) in radiology case-based learning.

    Science.gov (United States)

    Kourdioukova, Elena V; Verstraete, Koenraad L; Valcke, Martin

    2011-06-01

    The aim of this research was to explore (1) clinical years students' perceptions about radiology case-based learning within a computer supported collaborative learning (CSCL) setting, (2) an analysis of the collaborative learning process, and (3) the learning impact of collaborative work on the radiology cases. The first part of this study focuses on a more detailed analysis of a survey study about CSCL based case-based learning, set up in the context of a broader radiology curriculum innovation. The second part centers on a qualitative and quantitative analysis of 52 online collaborative learning discussions from 5th year and nearly graduating medical students. The collaborative work was based on 26 radiology cases regarding musculoskeletal radiology. The analysis of perceptions about collaborative learning on radiology cases reflects a rather neutral attitude that also does not differ significantly in students of different grade levels. Less advanced students are more positive about CSCL as compared to last year students. Outcome evaluation shows a significantly higher level of accuracy in identification of radiology key structures and in radiology diagnosis as well as in linking the radiological signs with available clinical information in nearly graduated students. No significant differences between different grade levels were found in accuracy of using medical terminology. Students appreciate computer supported collaborative learning settings when tackling radiology case-based learning. Scripted computer supported collaborative learning groups proved to be useful for both 5th and 7th year students in view of developing components of their radiology diagnostic approaches. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  4. Relations of plasma polyunsaturated Fatty acids with blood pressures during the 26th and 28th week of gestation in women of Chinese, Malay, and Indian ethnicity.

    Science.gov (United States)

    Lim, Wai-Yee; Chong, Mary; Calder, Philip C; Kwek, Kenneth; Chong, Yap-Seng; Gluckman, Peter D; Godfrey, Keith M; Saw, Seang-Mei; Pan, An

    2015-03-01

    Observational and intervention studies have reported inconsistent results of the relationship between polyunsaturated fatty acids (PUFAs) and hypertension during pregnancy. Here, we examined maternal plasma concentrations of n-3 and n-6 PUFAs between the 26th and the 28th week of gestation in relation to blood pressures and pregnancy-associated hypertension.We used data from a birth cohort study of 751 Chinese, Malay, and Indian women. Maternal peripheral systolic blood pressure (SBP) and diastolic blood pressure (DBP) were taken from the brachial arm, and central SBP and pulse pressures (PPs) were derived from radial artery pressure waveforms between the 26th and the 28th week of gestation. Pregnancy-associated hypertension (including gestational hypertension and preeclampsia) was ascertained from medical records. Plasma phosphatidylcholine n-3 and n-6 PUFAs were measured by gas chromatography and expressed as percentage of total fatty acids.Peripheral SBP was inversely associated with total n-3 PUFAs [-0.51 (95% confidence interval, CI, -0.89 to -0.13) mm Hg] and long-chain n-3 PUFAs [-0.52 (CI -0.92 to -0.13) mmHg]. Similar but weaker associations were observed for central SBP and PP. Dihomo-γ-linolenic acid was marginally positively associated with peripheral SBP, central SBP, and PP, whereas linoleic acid and total n-6 PUFAs showed no significant associations with blood pressures. We identified 28 pregnancy-associated hypertension cases, and 1% increase in total n-3 PUFAs was associated with a 24% lower odds of pregnancy-associated hypertension (odds ratio 0.76; 95% CI 0.60 to 0.97). Maternal ethnicity modified the PUFAs-blood pressure relations, with stronger inverse associations with n-3 PUFAs in Chinese women, and stronger positive associations with n-6 PUFAs in Indian women (P values for interaction ranged from 0.02 to 0.07).Higher n-3 PUFAs at midgestation are related to lower maternal blood pressures and pregnancy-associated hypertension in Asian women

  5. The Effects of Using Diorama on 7th Grade Students' Academic Achievement and Science Learning Skills

    Science.gov (United States)

    Aslan Efe, Hulya

    2017-01-01

    This study aims to investigate the effects of using diorama on 7th grade students' academic achievement and science learning skills in "human being and environment relation" unit. The participants were 49 (E:25, C:24) 7th grade students studying during 2015-16 academic year in Diyarbakir, Turkey. An achievement test and "science…

  6. Problem-Based Learning Method: Secondary Education 10th Grade Chemistry Course Mixtures Topic

    Science.gov (United States)

    Üce, Musa; Ates, Ismail

    2016-01-01

    In this research; aim was determining student achievement by comparing problem-based learning method with teacher-centered traditional method of teaching 10th grade chemistry lesson mixtures topic. Pretest-posttest control group research design is implemented. Research sample includes; two classes of (total of 48 students) an Anatolian High School…

  7. 7th International Conference in Methodologies and Intelligent Systems for Technology Enhanced Learning

    CERN Document Server

    Gennari, Rosella; Mascio, Tania; Rodríguez, Sara; Prieta, Fernando; Ramos, Carlos; Silveira, Ricardo

    2017-01-01

    This book presents the outcomes of the 7th International Conference in Methodologies and Intelligent Systems for Technology Enhanced Learning (MIS4TEL'17), hosted by the Polytechnic of Porto, Portugal from 21 to 23 June 2017. Expanding on the topics of the previous conferences, it provided an open forum for discussing intelligent systems for technology enhanced learning (TEL) and their roots in novel learning theories, empirical methodologies for their design or evaluation, stand-alone and web-based solutions, and makerspaces. It also fostered entrepreneurship and business startup ideas, bringing together researchers and developers from industry, education and the academic world to report on the latest scientific research, technical advances and methodologies.

  8. The Effect of Jigsaw Technique on 6th Graders' Learning of Force and Motion Unit and Their Science Attitudes and Motivation

    Science.gov (United States)

    Ural, Evrim; Ercan, Orhan; Gençoglan, Durdu Mehmet

    2017-01-01

    The study aims to investigate the effects of jigsaw technique on 6th graders' learning of "Force and Motion" unit, their science learning motivation and their attitudes towards science classes. The sample of the study consisted of 49 6th grade students from two different classes taking the Science and Technology course at a government…

  9. Blender Foundations The Essential Guide to Learning Blender 26

    CERN Document Server

    Hess, Roland

    2010-01-01

    Blender Foundations is the definitive resource for getting started with 3D art in Blender, one of the most popular 3D/Animation tools on the market . With the expert insight and experience of Roland Hess, noted Blender expert and author, animators and artists will learn the basics starting with the revised 2.6 interface, modeling tools, sculpting, lighting and materials through rendering, compositing and video editing. Some of the new features covered include the completely re-thought interface, the character animation and keying system, and the smoke simulator. More than just a tutorial gui

  10. Association of Grade Configuration with School Climate for 7th and 8th Grade Students

    Science.gov (United States)

    Malone, Marisa; Cornell, Dewey; Shukla, Kathan

    2017-01-01

    Educational authorities have questioned whether middle schools provide the best school climate for 7th and 8th grade students, and proposed that other grade configurations such as K-8th grade schools may provide a better learning environment. The purpose of this study was to compare 7th and 8th grade students' perceptions of 4 key features of…

  11. A Study of Learning Achievement and Learning Behavior in Biology on “Genes and Chromosomes” Using Storyline Teaching for 12th Grade Students

    OpenAIRE

    Ubonwan Leawudomchai; Kittima Panprueksa; Somsiri Singlop; Thanawuth Latwong

    2016-01-01

    The objectives of this research were to study learning achievement and learning behavior in Biology on “genes and chromosomes” using storyline teaching for 12th grade students. The sample for this research consisted of 36 twelfth grade students from Piboonbumpen Demonstration School in the first semester of 2014. The sample was randomly selected for the experimental group using cluster random sampling. The research instruments were the lesson plans using storyline teaching on g...

  12. Communicating Science to Impact Learning? A Phenomenological Inquiry into 4th and 5th Graders' Perceptions of Science Information Sources

    Science.gov (United States)

    Gelmez Burakgazi, Sevinc; Yildirim, Ali; Weeth Feinstein, Noah

    2016-04-01

    Rooted in science education and science communication studies, this study examines 4th and 5th grade students' perceptions of science information sources (SIS) and their use in communicating science to students. It combines situated learning theory with uses and gratifications theory in a qualitative phenomenological analysis. Data were gathered through classroom observations and interviews in four Turkish elementary schools. Focus group interviews with 47 students and individual interviews with 17 teachers and 10 parents were conducted. Participants identified a wide range of SIS, including TV, magazines, newspapers, internet, peers, teachers, families, science centers/museums, science exhibitions, textbooks, science books, and science camps. Students reported using various SIS in school-based and non-school contexts to satisfy their cognitive, affective, personal, and social integrative needs. SIS were used for science courses, homework/project assignments, examination/test preparations, and individual science-related research. Students assessed SIS in terms of the perceived accessibility of the sources, the quality of the content, and the content presentation. In particular, some sources such as teachers, families, TV, science magazines, textbooks, and science centers/museums ("directive sources") predictably led students to other sources such as teachers, families, internet, and science books ("directed sources"). A small number of sources crossed context boundaries, being useful in both school and out. Results shed light on the connection between science education and science communication in terms of promoting science learning.

  13. The Impact of a Teaching-Learning Program Based on a Brain-Based Learning on the Achievement of the Female Students of 9th Grade in Chemistry

    Science.gov (United States)

    Shabatat, Kawthar; Al-Tarawneh, Mohammed

    2016-01-01

    This study aimed at recognizing the impact of teaching-learning program based on a brain-based learning on the achievement of female students of 9th grade in chemistry, to accomplish the goal of this study the researchers designed instruments of: instructional plans, pre achievement and past achievement exams to use them for the study-validity and…

  14. Numerical Modelling of the 26th December 2004 Indian Ocean Tsunami for the Southeastern Coast of India

    Science.gov (United States)

    Ioualalen, M.; Arreaga-Vargas, P.; Pophet, N.; Chlieh, M.; Ilayaraja, K.; Ordoñez, J.; Renteria, W.; Pazmiño, N.

    2010-10-01

    A numerical simulation of the 26th December, 2004 Indian Ocean tsunami of the Tamil Nadu coastal zone is presented. The simulation approach is based on a fully nonlinear Boussinesq tsunami propagation model and included an accurate computational domain and a robust coseismic source. The simulation is first confronted to available tide gauge and runup observations. The agreement between observations and the predicted wave heights allowed a reasonable validation of the simulation. As a result, a full picture of the tsunami impact is provided over the entire coastal zone Tamil Nadu. The processes responsible for coastal vulnerability are discussed.

  15. Usage of Metaphors in Turkish Language Textbooks Used at 6th, 7th and 8th Grades

    Directory of Open Access Journals (Sweden)

    Esra Karakas

    2013-05-01

    Full Text Available The word “Metaphor”, which is equivalent to the terms “istiare” in Arabic or “eğretileme, transfer of idioms” in Turkish, consists of two parts. “Meta” means “later” or “with” whereas “phora” means transfer or conveyance of word. In the recent years metaphor has been the subject and focuses of several studies, and is used to express a concept or situation with another concept or situation. Starting from 1980s, researchers have studied metaphor and concurrently they examined usage of language. It is now been believed that using metaphors is appropriate in order to be able to understand any phenomenon. Metaphor can be used in encouraging learning and improving creative thinking; it can also provide hints for in-the-class methods, techniques and situations. In this context, metaphors are also essential components for Turkish language textbooks. The purpose of this study is to detect the uses of metaphor in Turkish language textbooks of 6th, 7th and 8th grade students. For this purpose the Turkish language textbooks of 6th, 7th and 8th grade students prepared by the Ministry of National Education (MEB were examined with “content analysis method. Considering that metaphors are effective in learning and improving creative thinking, the importance of using metaphors in textbooks is beyond discussion. The data collected throughout this study show that the metaphors detected in 7th and 8th grade Turkish language textbooks are less in number compared to those found in 6th grade Turkish language textbooks. Another important conclusion is that distribution of metaphors among units is not even. The conclusion of the study is that Turkish language textbooks are not prepared in a sensitive and choosy manner with this respect.

  16. The Effect on the 8th Grade Students' Attitude towards Statistics of Project Based Learning

    Science.gov (United States)

    Koparan, Timur; Güven, Bülent

    2014-01-01

    This study investigates the effect of the project based learning approach on 8th grade students' attitude towards statistics. With this aim, an attitude scale towards statistics was developed. Quasi-experimental research model was used in this study. Following this model in the control group the traditional method was applied to teach statistics…

  17. Implementation of Gasing Learning in ARCS Learning Strategy to Enhance Students’ Motivation in 9th Grade of Indonesian Junior High-School

    Directory of Open Access Journals (Sweden)

    Pri Ariadi Cahya Dinata

    2017-10-01

    Full Text Available The lack of motivation will affect to the students’ learning outcomes. The research was conducted to enhance the students’ motivation with the Gasing learning in the ARCS learning strategy on the static and dynamic electricity. The specific objectives of this research was to describe effect of the gasing learning on the students' learning motivation. The research consisted of 3 cycles of Hopkin’s Classroom Action Research  Model. Each cycle consists of the plan, the action/the observation, and the reflective. The data of students learning motivation obtained by questionnaires and be analyzed with method of successive interval (MSI. The findings of the research are: (1 the result of questionnaire of ARCS motivation in cycle I was 3.71, cycle II was 3,80, and cycle III was 3,99. These results indicate an increase in student learning motivation; (2 The completeness of students’ learning outcomes in cycle I was 68,18%, in cycle II was 90,90%, and in cycle III was 100%. It can be concluded that the Gasing learning in ARCS strategy can enhances students’motivation on static and dinamic electricity in 9th grade of Indonesian Junior High-School. The Gasing learning can be an alternative for the teachers to enhance students’ motivation in learning physics through the provision of comic media and calculations without formulas.

  18. Spatial Visualization as Mediating between Mathematics Learning Strategy and Mathematics Achievement among 8th Grade Students

    Science.gov (United States)

    Rabab'h, Belal; Veloo, Arsaythamby

    2015-01-01

    Jordanian 8th grade students revealed low achievement in mathematics through four periods (1999, 2003, 2007 & 2011) of Trends in International Mathematics and Science Study (TIMSS). This study aimed to determine whether spatial visualization mediates the affect of Mathematics Learning Strategies (MLS) factors namely mathematics attitude,…

  19. 4th Workshop on Combinations of Intelligent Methods and Applications

    CERN Document Server

    Palade, Vasile; Prentzas, Jim

    2016-01-01

    This volume includes extended and revised versions of the papers presented at the 4th Workshop on “Combinations of Intelligent Methods and Applications” (CIMA 2014) which was intended to become a forum for exchanging experience and ideas among researchers and practitioners dealing with combinations of different intelligent methods in Artificial Intelligence. The aim is to create integrated or hybrid methods that benefit from each of their components. Some of the existing presented efforts combine soft computing methods (fuzzy logic, neural networks and genetic algorithms). Another stream of efforts integrates case-based reasoning or machine learning with soft-computing methods. Some of the combinations have been more widely explored, like neuro-symbolic methods, neuro-fuzzy methods and methods combining rule-based and case-based reasoning. CIMA 2014 was held in conjunction with the 26th IEEE International Conference on Tools with Artificial Intelligence (ICTAI 2014). .

  20. Determination of the Relationship between 8th Grade Students Learning Styles and TIMSS Mathematics Achievement

    Science.gov (United States)

    Yilmaz, Gül Kaleli; Koparan, Timur; Hanci, Alper

    2016-01-01

    In this study, it is aimed to determination of the relationship between learning styles and TIMSS mathematics achievements of eighth grade students. Correlational research design that is one of the quantitative research methods, was used in this study. The sample of the research consists of 652 8th grade students 347 are male and 305 are female…

  1. Inflammatory Th17 cells promote depression-like behavior in mice

    Science.gov (United States)

    Beurel, Eléonore; Harrington, Laurie E.; Jope, Richard S.

    2012-01-01

    Background Recognition of substantial immune-neural interactions is revising dogmas about their insular actions and revealing that immune-neural interactions can substantially impact CNS functions. The inflammatory cytokine interleukin-6 promotes susceptibility to depression and drives production of inflammatory T helper 17 (Th17) T cells, raising the hypothesis that in mouse models Th17 cells promote susceptibility to depression-like behaviors. Methods Behavioral characteristics were measured in male mice administered Th17 cells, CD4+ cells, or vehicle, and in RORγT+/GFP mice or male mice treated with RORγT inhibitor or anti-IL-17A antibodies. Results Mouse brain Th17 cells were elevated by learned helplessness and chronic restraint stress, two common depression-like models. Th17 cell administration promoted learned helplessness in 89% of mice in a paradigm where no vehicle-treated mice developed learned helplessness, and impaired novelty suppressed feeding and social interaction behaviors. Mice deficient in the RORγT transcription factor necessary for Th17 cell production exhibited resistance to learned helplessness, identifying modulation of RORγT as a potential intervention. Treatment with the RORγT inhibitor SR1001, or anti-IL-17A antibodies to abrogate Th17 cell function, reduced Th17-dependent learned helplessness. Conclusions These findings indicate that Th17 cells are increased in the brain during depression-like states, promote depression-like behaviors in mice, and specifically inhibiting the production or function of Th17 cells reduces vulnerability to depression-like behavior, suggesting antidepressant effects may be attained by targeting Th17 cells. PMID:23174342

  2. Abstract Book of the NKS Workshop on Radioanalytical Chemistry, Risø, Roskilde, Denmark, 2-6th Sept. 2013

    DEFF Research Database (Denmark)

    from Germany, France, Slovenia, Korea, Turkey, and China. The workshop consists two part, 3 days lab practices and 2 days lectures/presentation. 3 lab practices were organized, i.e. (1) Radiochemical separation of Pu and ICP-MS measurement of Pu isotopes; (2) Radiochemical separation of 210Po and 226Ra......This report compiled all abstracts presented in the NKS Workshop on Radioanalytical Chemistry at Risø, Roskilde, Denmark in 2-6th Sept. 2013. Total 35 participants registered to the workshop, among them 18 from Sweden, 5 from Denmark, 3 from Finland, and 3 from Norway, there are also 6 participants...

  3. Learning by Doing: Teaching Multimedia Journalism through Coverage of the 50th Anniversary of "Freedom Summer"

    Science.gov (United States)

    Pain, Paromita; Masullo Chen, Gina; Campbell, Christopher P.

    2016-01-01

    In-depth qualitative interviews with participants of a high school journalism workshop reveal that immersing students in coverage of a historically important news event enhances learning of multimedia journalism. Study explores how using a team-based approach to coverage of the 50th anniversary of "Freedom Summer," a key event in…

  4. Radioactive fallout collected in Tokyo on November 26, 1955

    Energy Technology Data Exchange (ETDEWEB)

    Sugiura, Y; Kanazawa, T

    1956-01-01

    A large nuclear weapon test by Russia was reported November 23, 1955 as having occurred the previous day. Rain water and fallout samples taken in Tokyo before and after the 22nd indicated the test had produced a secondary fallout from some previous explosion. Rain water of the 21st and fallout of the 29th had radioactive content of 13 days half-life; fallout of the 26th, rain of the 27th 3 days half-life. Sample of the 26th consisted of 15 mg of sooty material giving nearly 2000 counts/min at that time.

  5. Proceeding of 26th domestic symposium on present and future of integrity monitoring technology in nuclear power generation facilities

    International Nuclear Information System (INIS)

    2000-06-01

    As the 26th domestic symposium of Atomic Energy Research Committee, the Japan Welding Engineering Society, the symposium was held titled as 'Current status and future of integrity monitoring techniques in nuclear power facilities'. Six speakers gave lectures titled as 'Maintenance and integrity monitoring in nuclear power plants', 'Present status of fatigue and creep-fatigue monitoring techniques in the US', 'Fatigue monitoring system in Tsuruga-1 nuclear power station', 'Vibration monitoring technique of rotational machine', 'SCC monitoring with electrochemical noise analysis' and Monitoring technique for corrosive environments and crack shape'. (T. Tanaka)

  6. The Effect of Project Based Learning on the Statistical Literacy Levels of Student 8th Grade

    Science.gov (United States)

    Koparan, Timur; Güven, Bülent

    2014-01-01

    This study examines the effect of project based learning on 8th grade students' statistical literacy levels. A performance test was developed for this aim. Quasi-experimental research model was used in this article. In this context, the statistics were taught with traditional method in the control group and it was taught using project based…

  7. Eurasian Higher Education Leaders' Forum: Higher Education and Modernization of the Economy: Innovative and Entrepreneurial Universities. Conference Proceedings (5th, Astana, Kazakhstan, May 26, 2016)

    Science.gov (United States)

    Sagintayeva, Aida, Ed.; Kurakbayev, Kairat, Ed.

    2016-01-01

    This collection of papers introduces the proceedings of the fifth Annual Conference--"Eurasian Higher Education Leaders' Forum" held on the 26th May, 2016 at Nazarbayev University in Astana, Kazakhstan. The contributors include university presidents, rectors, deans, directors of professional development and leadership programs, faculty…

  8. A synoptic picture of the impact of the 26th December 2004 Indian Ocean tsunami on the coast of Sri Lanka

    OpenAIRE

    Ioualalen, Mansour; Renteria, W.; Ilayaraja, K.; Chlieh, Mohamed; Arreaga-Vargas, R.

    2010-01-01

    A numerical simulation of the 26th December 2004 Indian Ocean tsunami for the entire coast of Sri Lanka is presented. The simulation approach is based on a fully nonlinear Boussinesq tsunami propagation model and a robust coseismic source. The simulation is first confronted to available measured wave height. The agreement between observations and the predicted wave heights allowed a reasonable validation of the simulation. As a result a synoptic picture of the tsunami impact is provided over ...

  9. The Effect of Process Oriented Guided Inquiry Learning (POGIL) on 11th Graders' Conceptual Understanding of Electrochemistry

    Science.gov (United States)

    Sen, Senol; Yilmaz, Ayhan; Geban, Ömer

    2016-01-01

    The purpose of this study was to investigate the effect of Process Oriented Guided Inquiry Learning (POGIL) method compared to traditional teaching method on 11th grade students' conceptual understanding of electrochemistry concepts. Participants were 115 students from a public school in Turkey. Nonequivalent control group design was used. Two…

  10. Proceedings of the 26th Seismic Research Review: Trends in Nuclear Explosion Monitoring

    International Nuclear Information System (INIS)

    Chavez, Francesca C.; Benson, Jody; Hanson, Stephanie; Mark, Carol; Wetovsky, Marvin A.

    2004-01-01

    These proceedings contain papers prepared for the 26th Seismic Research Review: Trends in Nuclear Explosion Monitoring, held 21-23 September, 2004 in Orlando, Florida. These papers represent the combined research related to ground-based nuclear explosion monitoring funded by the National Nuclear Security Administration (NNSA), Defense Threat Reduction Agency (DTRA), Air Force Research Laboratory (AFRL), US Army Space and Missile Defense Command, and other invited sponsors. The scientific objectives of the research are to improve the United States capability to detect, locate, and identify nuclear explosions. The purpose of the meeting is to provide the sponsoring agencies, as well as potential users, an opportunity to review research accomplished during the preceding year and to discuss areas of investigation for the coming year. For the researchers, it provides a forum for the exchange of scientific information toward achieving program goals, and an opportunity to discuss results and future plans. Paper topics include: seismic regionalization and calibration; detection and location of sources; wave propagation from source to receiver; the nature of seismic sources, including mining practices; hydroacoustic, infrasound, and radionuclide methods; on-site inspection; and data processing.

  11. Proceedings of the 26th Seismic Research Review: Trends in Nuclear Explosion Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Chavez, Francesca C [Editor; Benson, Jody [Editor; Hanson, Stephanie [Editor; Mark, Carol [Editor; Wetovsky, Marvin A [Editor

    2004-09-21

    These proceedings contain papers prepared for the 26th Seismic Research Review: Trends in Nuclear Explosion Monitoring, held 21-23 September, 2004 in Orlando, Florida. These papers represent the combined research related to ground-based nuclear explosion monitoring funded by the National Nuclear Security Administration (NNSA), Defense Threat Reduction Agency (DTRA), Air Force Research Laboratory (AFRL), US Army Space and Missile Defense Command, and other invited sponsors. The scientific objectives of the research are to improve the United States capability to detect, locate, and identify nuclear explosions. The purpose of the meeting is to provide the sponsoring agencies, as well as potential users, an opportunity to review research accomplished during the preceding year and to discuss areas of investigation for the coming year. For the researchers, it provides a forum for the exchange of scientific information toward achieving program goals, and an opportunity to discuss results and future plans. Paper topics include: seismic regionalization and calibration; detection and location of sources; wave propagation from source to receiver; the nature of seismic sources, including mining practices; hydroacoustic, infrasound, and radionuclide methods; on-site inspection; and data processing.

  12. Production of 231Pa and 232U by irradiation of 230Th/232Th mixtures

    International Nuclear Information System (INIS)

    Kluge, E.; Lieser, K.H.

    1981-01-01

    The production of 231 Pa and of 232 U by irradiating a 230 Th/ 232 Th mixture (containing 12 mol per cent 230 Th) in form of ThO 2 at a thermal neutron flux of 6.9 x 10 13 cm -2 s -1 for 4 months was investigated. Pa, U and Th were separated and the chemical yields were determined. 2.6% of the 230 Th were transformed into 231 Pa and 0.13% into 232 U. These values are higher than those calculated for a thermal flux, but lower than those calculated for a flux ratio epithermal to thermal = 0.03. 231 Pa and 232 U were isolated in form of a protactinium solution and of U 3 O 8 with 94.9 and 89.1% chemical yields, respectively. Foreign activities were not detected. Thorium was recuperated and isolated as ThO 2 , with a chemical yield of 93.6%. (orig.)

  13. Ability Of Mathematical Reasoning in SMK 10th Grade with LAPS- Heuristic using Performance Assessment

    Directory of Open Access Journals (Sweden)

    Aulia Nur Arivina

    2017-11-01

    Full Text Available The purposes of this research are: (1 Test the learning with LAPS-Heuristic model using performance assessment on 10th grade of Trigonometry material is complete, (2 to test the difference of students' mathematical reasoning ability on 10th grade of Trigonometry material between the learning model of LAPS-Heuristic using performance assessment, LAPS-Heuristic learning model with Expository learning model, (3 test the ability of mathematical reasoning with learning model of LAPS-Heuristik on Trigonometry material of SMK on 10th grade using performance assessment is increase. This is a quantitative research. The population is students of 10th grade of SMK 10 Semarang academic year 2016/2017 and the subject of research is selected by clustering random sampling. The results show that (1 Learning by model LAPS-Heuristic using performance assessment on 10th grade of Trigonometry material is complete (2 there are differences in students' mathematical reasoning ability on 10th grade of Trigonometry materials between LAPS-Heuristic learning model using performance assessment, LAPS-Heuristic learning model, and Expository learning model, (3 The ability of mathematical reasoning with learning model of LAPS-Heuristic on Trigonometry material of SMK class X using performance assessment increased.

  14. 20th Annual Systems Engineering Conference, Thursday, Volume 4

    Science.gov (United States)

    2017-10-26

    20th Annual Systems Engineering Conference October 23-26, 2017 | Waterford at Springfield | Springfield, VA NDIA.org/systemsengineering...Conference Program SYSTEMS ENGINEERING CONFERENCE 2 Welcome to the NDIA Systems Engineering Conference On behalf of the National Defense Industrial...Association’s Systems Engineering Division, I would like to extend a very warm welcome to the 20th Annual Systems Engineering Conference. Yes, the 20th Annual

  15. The Effectiveness of a Self Regulated Learning-Based Training Program on Improving Cognitive and Metacognitive EFL Reading Comprehension of 9th Graders with Reading Disabilities

    Science.gov (United States)

    Eissa, Mourad Ali

    2015-01-01

    The purpose of this study was to explore the effect of a self regulated learning intervention program on cognitive and metacognitive EFL reading comprehension of 9th graders with reading disabilities. The participants in this study were 40 9th Graders with reading disabilities, selected from two schools located in Baltim Educational Edara. A…

  16. Proceedings of the Annual Meeting [of the] North American Chapter of the International Group for the Psychology of Mathematics Education (24th, Athens, Georgia, October 26-29, 2002). Volumes 1-4.

    Science.gov (United States)

    Mewborn, Denise S., Ed.; Sztajn, Paola, Ed.; White, Dorothy Y., Ed.; Wiegel, Heide G., Ed.; Bryant, Robyn L., Ed.; Nooney, Kevin, Ed.

    The proceedings of the 24th annual meeting of the Psychology of Mathematics Education North American Chapter (PME-NA) contains research reports, plenaries, and poster presentations. Papers include: (1) "What Do We Believe about Teacher Learning and How Can We Learn With and From Our Beliefs?" (Deborah Loewenberg Ball); (2) "Toward Evidence for…

  17. Analysis of the learning curve for peroral endoscopic myotomy for esophageal achalasia: Single-center, two-operator experience.

    Science.gov (United States)

    Lv, Houning; Zhao, Ningning; Zheng, Zhongqing; Wang, Tao; Yang, Fang; Jiang, Xihui; Lin, Lin; Sun, Chao; Wang, Bangmao

    2017-05-01

    Peroral endoscopic myotomy (POEM) has emerged as an advanced technique for the treatment of achalasia, and defining the learning curve is mandatory. From August 2011 to June 2014, two operators in our institution (A&B) carried out POEM on 35 and 33 consecutive patients, respectively. Moving average and cumulative sum (CUSUM) methods were used to analyze the POEM learning curve for corrected operative time (cOT), referring to duration of per centimeter myotomy. Additionally, perioperative outcomes were compared among distinct learning curve phases. Using the moving average method, cOT reached a plateau at the 29th case and at the 24th case for operators A and B, respectively. CUSUM analysis identified three phases: initial learning period (Phase 1), efficiency period (Phase 2) and mastery period (Phase 3). The relatively smooth state in the CUSUM graph occurred at the 26th case and at the 24th case for operators A and B, respectively. Mean cOT of distinct phases for operator A were 8.32, 5.20 and 3.97 min, whereas they were 5.99, 3.06 and 3.75 min for operator B, respectively. Eckardt score and lower esophageal sphincter pressure significantly decreased during the 1-year follow-up period. Data were comparable regarding patient characteristics and perioperative outcomes. This single-center study demonstrated that expert endoscopists with experience in esophageal endoscopic submucosal dissection reached a plateau in learning of POEM after approximately 25 cases. © 2016 Japan Gastroenterological Endoscopy Society.

  18. Will learning to solve one-step equations pose a challenge to 8th grade students?

    Science.gov (United States)

    Ngu, Bing Hiong; Phan, Huy P.

    2017-08-01

    Assimilating multiple interactive elements simultaneously in working memory to allow understanding to occur, while solving an equation, would impose a high cognitive load. Element interactivity arises from the interaction between elements within and across operational and relational lines. Moreover, operating with special features (e.g. negative pronumeral) poses additional challenge to master equation solving skills. In an experiment, 41 8th grade students (girls = 16, boys = 25) sat for a pre-test, attended a session about equation solving, completed an acquisition phase which constituted the main intervention and were tested again in a post-test. The results showed that at post-test, students performed better on one-step equations tapping low rather than high element interactivity knowledge. In addition, students performed better on those one-step equations that contained no special features. Thus, both the degree of element interactivity and the operation with special features affect the challenge posed to 8th grade students on learning how to solve one-step equations.

  19. Computational mediation as factor of motivation and meaningful learning in education of sciences of 9th grade: astronomy topics

    Science.gov (United States)

    Da Silva, F. M.; Furtado, W. W.

    2012-10-01

    The main purpose of this study was to analyze the contribution of using hypertext and pedagogic mediation in search of a Meaningful Learning Process in Sciences. We investigate the usage of hypertext in the teaching and learning methods of Astronomy modules. A survey was conducted with students from the 9th grade of Primary School of a public school in the city of Goiânia, Goiás in Brazil. We have analyzed the possibilities that hypermedia can offer in the teaching and learning process, using as reference David Ausubel's Theory of Meaningful Learning. The study was divided into four phases: application of an initial questionnaire on students, development of didactic material (hypertext), six classes held in a computer lab with the use of hypermedia and a final questionnaire applied in the lab after classes. This research indicated that the use of hypertext linked to pedagogical mediation processes is seen as a motivational tool and has potential to foster to Meaningful Learning.

  20. CLIMA 2016 - proceedings of the 12th REHVA World Congress

    DEFF Research Database (Denmark)

    CLIMA 2016, 12th REHVA World Congress 2016 in Aalborg north of Denmark. Full reviewed papers presented at CLIMA 2016 is published in the conference proceedings. This volume contains the sessions number 24 + 25 +26 + 27 + 28 +29 + 30 from track "Building Performance".......CLIMA 2016, 12th REHVA World Congress 2016 in Aalborg north of Denmark. Full reviewed papers presented at CLIMA 2016 is published in the conference proceedings. This volume contains the sessions number 24 + 25 +26 + 27 + 28 +29 + 30 from track "Building Performance"....

  1. Summary of environmental study carried out by Bhabha Atomic Research Centre during 8th, 9th and 10th summer Indian expeditions to Antarctica

    International Nuclear Information System (INIS)

    Ramachandran, T.V.; Sathe, A.P.; Joshi, P.V.; Balani, M.C.

    1994-01-01

    The Bhabha Atomic Research Centre has participated in the 8th, 9th and 10th summer expeditions to Antarctica during 1988-91 period to carry out background radiation survey and to collect representative samples for radioactivity and heavy metal analyses. Spot measurements of ions as well as Radon daughter radionuclides were also carried out during the expeditions. Radon levels as well as heavy metal pollutant concentrations have been found to be quite low in general; however higher levels were observed at places where human activity is concentrated around the landing area as well as the laboratory site. The richness of the shelf waters at Antarctic were also realised through analysis of phytoplankton and zooplankton samples. (author). 25 refs., 5 figs., 26 tabs

  2. It participates in the 97th learning lecture, social meeting; Dai 97 kai Gakujitsu koenkai{center_dot}konshinkai ni sankashite

    Energy Technology Data Exchange (ETDEWEB)

    Maruta, T.; Moriya, M.; Izumi, K.

    1999-01-01

    An inorganic material academic meeting the 97th learning lecture, a social meeting and a study tour meeting were held for both days of (Thu) for 5 days in November 4 (Wed), the 10th year of Heisei. Contents of a lecture go into the large area to the thing that that method analysis technique structure analysis formation response thing materiality side was examined, the spot in the construction, building field like contents. A problem such as CO{sub 2} is an especially important problem as a negative legacy due to the industrial development, the diffusion of the car, and so on. (NEDO)

  3. Heterogeneous transgene expression in the retinas of the TH-RFP, TH-Cre, TH-BAC-Cre and DAT-Cre mouse lines.

    Science.gov (United States)

    Vuong, H E; Pérez de Sevilla Müller, L; Hardi, C N; McMahon, D G; Brecha, N C

    2015-10-29

    Transgenic mouse lines are essential tools for understanding the connectivity, physiology and function of neuronal circuits, including those in the retina. This report compares transgene expression in the retina of a tyrosine hydroxylase (TH)-red fluorescent protein (RFP) mouse line with three catecholamine-related Cre recombinase mouse lines [TH-bacterial artificial chromosome (BAC)-, TH-, and dopamine transporter (DAT)-Cre] that were crossed with a ROSA26-tdTomato reporter line. Retinas were evaluated and immunostained with commonly used antibodies including those directed to TH, GABA and glycine to characterize the RFP or tdTomato fluorescent-labeled amacrine cells, and an antibody directed to RNA-binding protein with multiple splicing to identify ganglion cells. In TH-RFP retinas, types 1 and 2 dopamine (DA) amacrine cells were identified by their characteristic cellular morphology and type 1 DA cells by their expression of TH immunoreactivity. In the TH-BAC-, TH-, and DAT-tdTomato retinas, less than 1%, ∼ 6%, and 0%, respectively, of the fluorescent cells were the expected type 1 DA amacrine cells. Instead, in the TH-BAC-tdTomato retinas, fluorescently labeled AII amacrine cells were predominant, with some medium diameter ganglion cells. In TH-tdTomato retinas, fluorescence was in multiple neurochemical amacrine cell types, including four types of polyaxonal amacrine cells. In DAT-tdTomato retinas, fluorescence was in GABA immunoreactive amacrine cells, including two types of bistratified and two types of monostratified amacrine cells. Although each of the Cre lines was generated with the intent to specifically label DA cells, our findings show a cellular diversity in Cre expression in the adult retina and indicate the importance of careful characterization of transgene labeling patterns. These mouse lines with their distinctive cellular labeling patterns will be useful tools for future studies of retinal function and visual processing. Published by Elsevier

  4. Complexes of Th(IV) perchlorates, nitrates and thiocyanates with some heterocyclic bases

    International Nuclear Information System (INIS)

    Agarwal, R.K.; Srivastava, A.K.; Srivastava, M.; Bhakru, N.; Srivastava, T.N.

    1980-01-01

    Some Th(IV) perchlorate complexes of heterocyclic bases have been reported previously. Adducts of Th(IV) nitrates and thiocyanates with some heterocyclic N-oxides have been prepared and physico-chemical properties investigated. Comparatively little is known about the complexes of Th(IV) ion with the ligands containing nitrogen atom acting as electron donating centres. In view of this, the adducts of Th(IV) ion with certain nitrogen heterocyclic bases such as pyridine (Py), α-picoline (Pic), 2-amino pyridine (NH 2 Py), 2:4-lutidine (2,4LN), 2:6-lutidine, (2,6LN), quinoline (Q), isoquinoline (Isoq), 2,2'-bipyridine (Bipy) and 1,10-phenanthroline (Phen) were synthesised and characterised by analysis and IR absorption spectra. The results are presented and discussed. (author)

  5. The permanent electric dipole moment of thorium sulfide, ThS.

    Science.gov (United States)

    Le, Anh; Heaven, Michael C; Steimle, Timothy C

    2014-01-14

    Numerous rotational lines of the {18.26}1-X(1)Σ(+) band system of thorium sulfide, ThS, were recorded near 547.6 nm at a resolution of approximately 30 MHz. Measurements were made under field-free conditions, and in the presence of a static electric field. The field-free spectrum was analyzed to produce rotational and Λ-doubling parameters. The Stark shifts induced by the electric field were analyzed to determine permanent electric dipole moments, μ⃗el, of 4.58(10) D and 6.72(5) D for the X(1)Σ(+) (v = 0) and {18.26}1 states, respectively. The results are compared with the predictions of previous and new electronic structure calculations for ThS, and the properties of isovalent ThO.

  6. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Mobile Learning (13th, Budapest, Hungary, April 10-12, 2017)

    Science.gov (United States)

    Sánchez, Inmaculada Arnedillo, Ed.; Isaías, Pedro, Ed.

    2017-01-01

    These proceedings contain the papers and posters of the 13th International Conference on Mobile Learning 2017, which was organised by the International Association for Development of the Information Society (IADIS), in Budapest, Hungary, April 10-12, 2017. The Mobile Learning 2017 Conference seeks to provide a forum for the presentation and…

  7. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Mobile Learning (11th, Madeira, Portugal, March 14-16, 2015)

    Science.gov (United States)

    Sánchez, Inmaculada Arnedillo, Ed.; Isaías, Pedro, Ed.

    2015-01-01

    These proceedings contain the papers and posters of the 11th International Conference on Mobile Learning 2015, which was organised by the International Association for Development of the Information Society, in Madeira, Portugal, March 14-16, 2015. The Mobile Learning 2015 Conference seeks to provide a forum for the presentation and discussion of…

  8. Modeling of Teaching 5th-7th-Grade Boys Physical Exercises

    Directory of Open Access Journals (Sweden)

    Т. Г. Абдулхалікова

    2017-09-01

    Full Text Available The research objective is to determine the effectiveness of orthogonal variants of teaching 5th-7th graders physical exercises. Materials and methods. The participants in the research were boys of the 5th grade (n = 32, 6th grade (n = 40, 7th grade (n = 52. To achieve the tasks set, the research used the following methods: analysis of scientific and methodological literature; pedagogical testing, pedagogical observation, timing of educational tasks; pedagogical experiment, medical and biological research methods; methods of mathematical statistics, methods of mathematical experiment planning. In order to achieve the objective set, the research has studied the effect of different variants of the educational process structure, namely: the number of repetitions (х1 and rest intervals (х2 when learning the technique of performing physical exercises. The research has conducted a complete factor experiment of type 22. According to the experiment plan, the 5th-7th graders were divided into training groups. In total, there were 12 experimental groups organized. Research results. The analysis of the regression equations shows that the teaching of physical exercises to the 5th-7th-grade boys is mostly influenced by rest intervals between repetitions (х2. The number of repetitions (х1 has somewhat less influence. The interaction of these factors is insignificant when teaching physical exercises and becomes much more influential only when teaching a switch leg pull-over exercise (х1х2. Conclusions. To increase the effectiveness of teaching 5th-7th graders physical exercises, it is necessary to shorten rest intervals between repetition to 60 s and to reduce the number of repetitions to six. When teaching boys the switch leg pull-over exercise, rest intervals should be increased to 120 s and the number of repetitions — to twelve.

  9. 20th Annual Systems Engineering Conference. Volume 1, Monday-Tuesday

    Science.gov (United States)

    2017-10-26

    20th Annual Systems Engineering Conference October 23-26, 2017 | Waterford at Springfield | Springfield, VA NDIA.org/systemsengineering...Conference Program SYSTEMS ENGINEERING CONFERENCE 2 Welcome to the NDIA Systems Engineering Conference On behalf of the National Defense Industrial...Association’s Systems Engineering Division, I would like to extend a very warm welcome to the 20th Annual Systems Engineering Conference. Yes, the 20th Annual

  10. Repercussões maternas e perinatais da ruptura prematura das membranas até a 26ª semana gestacional Maternal and perinatal outcomes of premature rupture of the membranes up to the 26th week of gestation

    Directory of Open Access Journals (Sweden)

    Alessandra Maria Mont'Alverne Pierre

    2003-03-01

    Full Text Available OBJETIVO: avaliar o prognóstico materno e perinatal em casos com amniorrexe prematura ocorridas até a 26ª semana de gravidez. MÉTODOS: análise retrospectiva dos casos de ruptura prematura das membranas ocorridas até a 26ª semana gestacional, sem sinais de trabalho de parto, sem qualquer tratamento para esta condição antes da admissão, acompanhados no período de janeiro de 1994 a dezembro de 1999. Os casos com idade gestacional menor que 22 semanas e peso ao nascimento inferior a 500 gramas foram excluídos. A amniorrexe foi confirmada pelo exame especular. Em caso de dúvida realizaram-se o teste da cristalização e a determinação do pH. Todas as grávidas foram submetidas a exame ultra-sonográfico para determinação da idade gestacional e índice de líquido amniótico. Os dados referentes ao resultado final da gravidez e as conseqüências para mãe, feto e neonato foram tabulados. RESULTADOS: preencheram os critérios de inclusão 29 casos de amniorrexe prematura. A ruptura ocorreu entre a 17ª e a 26ª semana, com média de 23,6 semanas. A duração média do período de latência foi de 21,7 dias. Ocorreram 22 partos vaginais espontâneos e três induzidos, além de quatro cesarianas. Houve sinais de infecção antes do parto em seis casos. Em 37,9% dos casos foram administrados antibióticos e em 6,9%, corticóides. Nenhuma paciente foi submetida a tocólise. Ocorreram três óbitos fetais e 25 neonatais. Apenas um recém-nascido sobreviveu, tendo permanecido na unidade de neonatologia por 19 dias devido a infecção e síndrome do desconforto respiratório. Não ocorreram óbitos maternos. CONCLUSÃO: a amniorrexe prematura até a 26ª semana gestacional tem sido doença com prognóstico extremamente sombrio para fetos e neonatos em nossa instituição.PURPOSE: to evaluate maternal and perinatal outcomes of premature rupture of membranes up to the 26th week of gestation. METHODS: retrospective analysis of the cases of

  11. The permanent electric dipole moment of thorium sulfide, ThS

    Energy Technology Data Exchange (ETDEWEB)

    Le, Anh; Steimle, Timothy C., E-mail: Tsteimle@ASU.edu [Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287-1604 (United States); Heaven, Michael C. [Department of Chemistry, Emory University, Atlanta, Georgia 30322 (United States)

    2014-01-14

    Numerous rotational lines of the (18.26)1-X{sup 1}Σ{sup +} band system of thorium sulfide, ThS, were recorded near 547.6 nm at a resolution of approximately 30 MHz. Measurements were made under field-free conditions, and in the presence of a static electric field. The field-free spectrum was analyzed to produce rotational and Λ-doubling parameters. The Stark shifts induced by the electric field were analyzed to determine permanent electric dipole moments, μ{sup -vector}{sub el}, of 4.58(10) D and 6.72(5) D for the X{sup 1}Σ{sup +} (v = 0) and (18.26)1 states, respectively. The results are compared with the predictions of previous and new electronic structure calculations for ThS, and the properties of isovalent ThO.

  12. The 13th International Workshop on Targetry and Target Chemistry Proceedings

    DEFF Research Database (Denmark)

    Haroun, Samar; Givskov, Alex David; Jensen, Mikael

    in situ target chemistry and the engineering required to optimize production yields. In the workshop, experience, ideas and information are freely and openly shared; learning and collaborations are fostered, with active participation by all attendees. This participation includes both formal and informal......This report contains the complete proceedings of the 13th International Workshop on Targetry and Target Chemistry. The Workshop was held at Risø National Laboratory for Sustainable Energy on July 26-28 2010. The workshop deals with the development of methods and systems for efficient production...... of the WTTC is to advance the science associated with radioisotope production targetry. The Workshops are designed to bring experienced targetry scientists together with newcomers to the field, both from industry and academia, to discuss issues of targetry and target chemistry and approaches to exploring...

  13. Comparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats.

    Science.gov (United States)

    Liu, Gang; Liu, Chao; Zhang, Xue-Ning

    2015-09-01

    The present study aimed to examine the neurophysiological mechanisms of the 2,6-diisopropylphenol and N-methyl-D-aspartate (NMDA) receptor antagonist against learning and memory impairment, induced by electroconvulsive therapy (ECT). A total of 48 adult depressed rats without olfactory bulbs were randomly divided into six experimental groups: i) saline; ii) 10 mg/kg MK‑801; iii) 10 mg/kg MK‑801 and a course of ECT; iv) 200 mg/kg 2,6‑diisopropylphenol; v) 200 mg/kg 2,6‑diisopropylphenol and a course of ECT; and vi) saline and a course of ECT. The learning and memory abilities of the rats were assessed using a Morris water maze 1 day after a course of ECT. The hippocampus was removed 1 day after assessment using the Morris water maze assessment. The content of glutamate in the hippocampus was detected using high‑performance liquid chromatography. The expression levels of p‑AT8Ser202 and GSK‑3β1H8 in the hippocampus were determined using immunohistochemical staining and western blot analysis. The results demonstrated that the 2,6‑diisopropylphenol NMDA receptor antagonist, MK‑801 and ECT induced learning and memory impairment in the depressed rats. The glutamate content was significantly upregulated by ECT, reduced by 2,6‑diisopropylphenol, and was unaffected by the NMDA receptor antagonist in the hippocampus of the depressed rats. Tau protein hyperphosphorylation in the hippocampus was upregulated by ECT, but was reduced by 2,6‑diisopropylphenol and the MK‑801 NMDA receptor antagonist. It was also demonstrated that 2,6‑diisopropylphenol prevented learning and memory impairment and reduced the hyperphosphorylation of the Tau protein, which was induced by eECT. GSK‑3β was found to be the key protein involved in this signaling pathway. The ECT reduced the learning and memory impairment, caused by hyperphosphorylation of the Tau protein, in the depressed rats by upregulating the glutamate content.

  14. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Mobile Learning (12th, Vilamoura, Algarve, Portugal, April 9-11, 2016)

    Science.gov (United States)

    Sánchez, Inmaculada Arnedillo, Ed.; Isaías, Pedro, Ed.

    2016-01-01

    These proceedings contain the papers of the 12th International Conference on Mobile Learning 2016, which was organized by the International Association for Development of the Information Society, in Vilamoura, Algarve, Portugal, April 9-11, 2016. The Mobile Learning 2016 Conference seeks to provide a forum for the presentation and discussion of…

  15. 3D Visualization Types in Multimedia Applications for Science Learning: A Case Study for 8th Grade Students in Greece

    Science.gov (United States)

    Korakakis, G.; Pavlatou, E. A.; Palyvos, J. A.; Spyrellis, N.

    2009-01-01

    This research aims to determine whether the use of specific types of visualization (3D illustration, 3D animation, and interactive 3D animation) combined with narration and text, contributes to the learning process of 13- and 14- years-old students in science courses. The study was carried out with 212 8th grade students in Greece. This…

  16. Ability Of Mathematical Reasoning in SMK 10th Grade with LAPS- Heuristic using Performance Assessment

    OpenAIRE

    Aulia Nur Arivina; Masrukan Masrukan; Ardhi Prabowo

    2017-01-01

    The purposes of this research are: (1) Test the learning with LAPS-Heuristic model using performance assessment on 10th grade of Trigonometry material is complete, (2) to test the difference of students' mathematical reasoning ability on 10th grade of Trigonometry material between the learning model of LAPS-Heuristic using performance assessment, LAPS-Heuristic learning model with Expository learning model, (3) test the ability of mathematical reasoning with learning model of LAPS-Heuristik o...

  17. Isoseismals for the Kutch earthquake of 26th January 2001

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    2001-01-26

    Jan 26, 2001 ... of schools, hospitals, community inns and govern- ment offices. The survey ... Failure of columns occurred at ground storey level in most multistoreyed ... Acknowledgements. Professor and Head, Department of Earthquake.

  18. Heating and melting of small icy satellites by the decay of Al-26

    International Nuclear Information System (INIS)

    Prialnik, D.; Bar-Nun, A.

    1990-01-01

    The effect of radiogenic heating due to Al-26 on the thermal evolution of small icy satellites is studied. The object is to find the extent of internal melting as a function of the satellite radius and of the initial Al-26 abundance. The implicit assumption, based on observations of young stars, is that planet and satellite accretion occurred on a time scale of about 10 to the 6th yr (comparable with the lifetime of Al-26). The icy satellites are modeled as spheres of initially amorphous ice, with chondritic abundances of K-40, Th-232, U-235, and U-238, corresponding to an ice/dust mass ratio of 1. Evolutionary calculations are carried out, spanning 4.5 x 10 to the 9th yr, for different combinations of the two free parameters. Heat transfer by subsolidus convection is neglected for these small satellites. The main conclusion is that the initial Al-26 abundance capable of melting icy bodies of satellite size to a significant extent is more than 10 times lower than that prevailing in the interstellar medium (or that inferred from the Ca-Al rich inclusions of the Allende meteorite, about 7 x 10 to the -7th by mass). 34 refs

  19. Heating and melting of small icy satellites by the decay of Al-26

    Science.gov (United States)

    Prialnik, Dina; Bar-Nun, Akiva

    1990-05-01

    The effect of radiogenic heating due to Al-26 on the thermal evolution of small icy satellites is studied. The object is to find the extent of internal melting as a function of the satellite radius and of the initial Al-26 abundance. The implicit assumption, based on observations of young stars, is that planet and satellite accretion occurred on a time scale of about 10 to the 6th yr (comparable with the lifetime of Al-26. The icy satellites are modeled as spheres of initially amorphous ice, with chondritic abundances of K-40, Th-232, U-235, and U-238, corresponding to an ice/dust mass ratio of 1. Evolutionary calculations are carried out, spanning 4.5 x 10 to the 9th yr, for different combinations of the two free parameters. Heat transfer by subsolidus convection is neglected for these small satellites. The main conclusion is that the initial Al-26 abundance capable of melting icy bodies of satellite size to a significant extent is more than 10 times lower than that prevailing in the interstellar medium (or that inferred from the Ca-Al rich inclusions of the Allende meteorite, about 7 x 10 to the -7th by mass).

  20. Learning design guided learning analytics in MOOCs

    NARCIS (Netherlands)

    Brouns, Francis; Firssova, Olga

    2016-01-01

    Poster presentation for our paper Brouns, F., & Firssova, O. (2016, October).The role of learning design and learning analytics in MOOCs. Paper presented at 9th EDEN Research Workshop, Oldenburg, Germany.

  1. Effects of γ-rays on Th1 and Th2 immune function of mice

    International Nuclear Information System (INIS)

    Jin Wei; Cui Yufang; An Xiaoxia; Xu Han; Dong Bo; Liu Xiaolan; Luo Qingliang

    2007-01-01

    Objective: To observe the effects of 6 Gy whole body γ-irradiation on immune function of Th1 and Th2 in mouse, and to investigate the cellular and molecular mechanism of immune system injury induced by irradiation. Methods: Surface marker and intracellular cytokines of lymphocytes were stained with fluorescence-labeled monoclonal antibodies, then the changes of lymphocyte subpopulations, especially the Th1 and Th2 in mouse peripheral blood and spleen were analyzed by flow cytometry. Results: (1) 1 d after 6 Gy y- irradiation, lymphocytic subsets of CD 19 + and CD 8 + in spleen decreased apparently and the percentages of them were only 30% and 41% of control groups respectively (P 19 + and 14 d for CD 8 + respectively, however, up to 21 d post-irradiation they still did not return to control level. (2) Th1 subpopulations in mouse peripheral blood and spleen were significantly reduced at 1 d after irradiation and were only 2.6% and 7.6% of control groups (P 4 + / CD 8 + were significantly increased at 1 d post-irradiation in mouse spleen because of swift reduction of CD 8 + cells. Interestingly, either in peripheral blood or in spleen in irradiated mice, the ratio of Th1/Th2 were evidently raised because of the decrement of Th1 cells, exhibited obviously a phenomenon of predominant immune response of Th2 cells. Conclusions: It is suggested that the depression of mouse immune function induced by 6 Gy γ-irradiation might be caused by changes of CD 4 + /CD 8 + ratio, especially the imbalance of Th1/Th2 function subpopulations. It is shown that the imbalance of Th1/Th2 function subpopulations plays an important role in radiation-induced immune injury, thus providing a better insight into the molecular mechanism and new strategies for prevent and treatment measures of immune injury by irradiation. (authors)

  2. Statistical parameters of Bhuj earthquake sequence of January 26th ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    2001-01-26

    Jan 26, 2001 ... 6.9) took a heavy toll of human lives, exceeding. 17000 (Anon 2001b). The damage .... Resources & Water Supply Dept., Vadodara, India. (unpublished) ... cisco; California: W.H. Freeman & Co, Inc.) Scholz C H 1968 Micro ...

  3. Seamless learning: Technology-enhanced learning from practical experiences across contexts

    NARCIS (Netherlands)

    Rusman, Ellen

    2018-01-01

    Rusman, E. (2018, 8th of June). Seamless learning: Technology-enhanced learning from practical experiences across contexts. Keynote presentation at the Seamless learning conference, Maastricht, The Netherlands. http://www.ou.nl/slc

  4. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on e-Learning (Prague, Czech Republic, July 23-26, 2013)

    Science.gov (United States)

    Nunes, Miguel Baptista, Ed.; McPherson, Maggie, Ed.

    2013-01-01

    These proceedings contain the papers of the International Conference e-Learning 2013, which was organised by the International Association for Development of the Information Society and is part of the Multi Conference on Computer Science and Information Systems (Prague, Czech Republic, July 23-26, 2013). The e-Learning 2013 conference aims to…

  5. The Effect of the Conceptual Change Oriented Instruction through Cooperative Learning on 4th Grade Students' Understanding of Earth and Sky Concepts

    Science.gov (United States)

    Celikten, Oksan; Ipekcioglu, Sevgi; Ertepinar, Hamide; Geban, Omer

    2012-01-01

    The purpose of this study was to compare the effectiveness of the conceptual change oriented instruction through cooperative learning (CCICL) and traditional science instruction (TI) on 4th grade students' understanding of earth and sky concepts and their attitudes toward earth and sky concepts. In this study, 56 fourth grade students from the…

  6. The 25th anniversary of the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    Osztrovszki, Gy.

    1982-01-01

    The leader of the Hungarian delegation at the 26th General Assembly of the International Atomic Energy (IAEA) held in Vienna in September, 1982, on the occasion of the IAEA's 25th anniversary, presented a short review of the IAEA's activities during its existence, the Hungarian participation in them and Hungary's efforts in the peaceful uses of the nuclear energy. (A.L.)

  7. An Exploratory Study of 4th, 5th, and 6th Grade Summer Camp Participants’ Attitudes and Intentions Towards Physical Activity

    Directory of Open Access Journals (Sweden)

    Melissa Cater

    2015-10-01

    Full Text Available Physical inactivity is a growing problem among children, particularly school-aged youth. Research suggests children are especially prone to inactivity in the summer months when access to structured school-time and extra-curricular activities is reduced. Community programs like residential summer camps offer an excellent environment for engaging children in enjoyable physical activities while also helping them learn to be more physically active when they return home. Pre-existing attitudes often influence how much change a program inspires in an individual. The purpose of this study was to explore 4th, 5th, and 6th grade summer camp participants’ attitudes towards physical activity. Results of this study indicate that youth have a fairly neutral, though positive, attitude towards physical activity and that parental support of physical activity is still extremely important, even at this age. Campers also indicated relatively high intentions to remain physically active in the two weeks after the camp ended

  8. Transferring an Outcome-Oriented Learning Architecture to an IT Learning Game

    NARCIS (Netherlands)

    Schmitz, Birgit; Klemke, Roland; Totschnig, Michael; Czauderna, André; Specht, Marcus

    2011-01-01

    Schmitz, B., Klemke, R., Totschnig, M., Czauderna, A., & Specht, M. (2011, 23 September). Transferring an outcome-oriented learning architecture to an IT learning game. Presented at the 6th European conference on Technology enhanced learning: towards ubiquitous learning (EC-TEL 2011), Palermo,

  9. 5th Annual Pan-European Science and Big Physics Symposium on March 5th, 2012, Zurich, Switzerland

    CERN Multimedia

    Balle, Ch

    2012-01-01

    The 5th Annual Pan-European Science and Big Physics Symposium on March 5th is a technical workshop that covers topics in the areas of control, measurement and diagnostics for accelerators, cyclotrons, tokamaks and telescopes. The symposium brings together over 60 scientists and engineers from major research labs around the world such as CERN, PSI, INFN, NPL, ESRF and other research institutions. Attend this event to share ideas and results and to learn from the presentations of your peers from different labs and experiments worldwide.

  10. Mass and energy distribution of fragments of sup 232 Th nucleus fission by 21-26. 4 MeV. alpha. -particles. Massovye i ehnergeticheskie raspredeleniya oskolkov deleniya yadra sup 232 Th. alpha. -chastitsami s ehnergiyami 21-26,4 MehV

    Energy Technology Data Exchange (ETDEWEB)

    Zaika, N I; Kibkalo, Yu V; Parlag, O A; Sikora, D I; Tokarev, V P; Shityuk, V A [AN Ukrainskoj SSR, Kiev (Ukrainian SSR). Inst. Yadernykh Issledovanij

    1989-04-01

    Two-parameter measurements of the mass and energy distributions of fission products in the fission of {sup 232}Th by 21.0-26.4 MeV {alpha}-particles (h=1 MeV) are conducted using the correlation method. The obtained results show that in the region under investigation the average total kinetic energies of the fission products E-bar{sub k} have no noticeable variations within the experimental error of {plus minus} 1.5 MeV and the dispersion {sigma}{sup 2}E{sub k} slowly increases. For the E-bar{sub k} mass dependence of heavy fraction the maximum is observed at A=132, that confirms a hypothesis on the influence of the closed-shell effects at the magic numbers of Z=50 and N=82. Assuming the existence of different barrier values for two models of the fission the ratio of symmetric and asymmetric fission yields are analyzed in the statistical model. It is shown that the barrier difference for two modes of fission is 1.3-1.4 MeV, which is in good agreement with the model of two fission modes.

  11. ANALYSIS OF MATHEMATIC REPRESENTATION ABILITY OF JUNIOR HIGH SCHOOL STUDENTS IN THE IMPLEMENTATION OF GUIDED INQUIRY LEARNING

    Directory of Open Access Journals (Sweden)

    Yumiati Yumiati

    2017-09-01

    Full Text Available The objective of this research is to analysing the different on upgrade the student’s math representation that obtained the guided inquiry learning and conventional learning. This research conducted by applying experiment method with nonequivalent control group design at one school. Which becoming research subject are students of Dharma Karya UT Middle School at 8th Grade. 8-2 class selected as control class (19 students and 8-3 class selected as experiment class (20 students. Before and after learning process, two classes given the test of math representation with reliability is 0.70 (high category. The magnitude of the increasing in students’ math representation student group of guided inquiry learning group is 0.41 included as medium category. Meanwhile, the increasing students’ math representation student group of conventional learning is 0.26 included as low category. In conclusion, the hypothesis of the ability of the mathematical representation of students who learning with guided inquiry is better than students with conventional learning is accepted.

  12. Computer Assisted Language Learning (CALL): Using Internet for Effective Language Learning

    NARCIS (Netherlands)

    Kremenska, Anelly

    2006-01-01

    Please, cite this publication as: Kremenska, A. (2006). Computer Assisted Language Learning (CALL): Using Internet for Effective Language Learning. Proceedings of International Workshop in Learning Networks for Lifelong Competence Development, TENCompetence Conference. March 30th-31st, Sofia,

  13. An Analysis of the Relationship between the Learning Process and Learning Motivation Profiles of Japanese Pharmacy Students Using Structural Equation Modeling.

    Science.gov (United States)

    Yamamura, Shigeo; Takehira, Rieko

    2018-04-23

    Pharmacy students in Japan have to maintain strong motivation to learn for six years during their education. The authors explored the students’ learning structure. All pharmacy students in their 4th through to 6th year at Josai International University participated in the survey. The revised two factor study process questionnaire and science motivation questionnaire II were used to assess their learning process and learning motivation profiles, respectively. Structural equation modeling (SEM) was used to examine a causal relationship between the latent variables in the learning process and those in the learning motivation profile. The learning structure was modeled on the idea that the learning process affects the learning motivation profile of respondents. In the multi-group SEM, the estimated mean of the deep learning to learning motivation profile increased just after their clinical clerkship for 6th year students. This indicated that the clinical experience benefited students’ deep learning, which is probably because the experience of meeting with real patients encourages meaningful learning in pharmacy studies.

  14. Determination of Motivation of 5th Grade Students Living in Rural and Urban Environments towards Science Learning and Their Attitudes towards Science-Technology Course

    Science.gov (United States)

    Kenar, Ismail; Köse, Mücahit; Demir, Halil Ibrahim

    2016-01-01

    In this research, determination of motivation of 5th grade students living in rural and urban environments towards science learning and their attitudes towards science-technology course is aimed. This research is conducted based on descriptive survey model. Samples are selected through teleological model in accordance with the aim of this…

  15. The 18th Annual Conference on Finance and Accounting

    OpenAIRE

    YEŞİLÇELEBİ, Gül

    2017-01-01

    Abstract. In this paper, the evaluation of the 18th Annual Conference on Finance and Accounting held on 26 May 2017 in Prague, Czech Republic will be mentioned.Keywords. Accounting, Finance, Czech Republic.JEL. M40, G10.

  16. JANNAF 28th Propellant Development and Characterization Subcommittee and 17th Safety and Environmental Protection Subcommittee Joint Meeting. Volume 1

    Science.gov (United States)

    Cocchiaro, James E. (Editor); Mulder, Edwin J. (Editor); Gomez-Knight, Sylvia J. (Editor)

    1999-01-01

    This volume contains 37 unclassified/unlimited-distribution technical papers that were presented at the JANNAF 28th Propellant Development & Characterization Subcommittee (PDCS) and 17th Safety & Environmental Protection Subcommittee (S&EPS) Joint Meeting, held 26-30 April 1999 at the Town & Country Hotel and the Naval Submarine Base, San Diego, California. Volume II contains 29 unclassified/limited-distribution papers that were presented at the 28th PDCS and 17th S&EPS Joint Meeting. Volume III contains a classified paper that was presented at the 28th PDCS Meeting on 27 April 1999. Topics covered in PDCS sessions include: solid propellant rheology; solid propellant surveillance and aging; propellant process engineering; new solid propellant ingredients and formulation development; reduced toxicity liquid propellants; characterization of hypergolic propellants; and solid propellant chemical analysis methods. Topics covered in S&EPS sessions include: space launch range safety; liquid propellant hazards; vapor detection methods for toxic propellant vapors and other hazardous gases; toxicity of propellants, ingredients, and propellant combustion products; personal protective equipment for toxic liquid propellants; and demilitarization/treatment of energetic material wastes.

  17. 78th Annual Meeting of the Psychometric Society

    CERN Document Server

    Bolt, Daniel; Ark, L; Wang, Wen-Chung

    2015-01-01

    The 78th Annual Meeting of the Psychometric Society (IMPS) builds on the Psychometric Society's mission to share quantitative methods relevant to psychology. The chapters of this volume present cutting-edge work in the field. Topics include studies of item response theory, computerized adaptive testing, cognitive diagnostic modeling, and psychological scaling. Additional psychometric topics relate to structural equation modeling, factor analysis, causal modeling, mediation, missing data methods, and longitudinal data analysis, among others. The papers in this volume will be especially useful for researchers in the social sciences who use quantitative methods. Prior knowledge of statistical methods is recommended. The 78th annual meeting took place in Arnhem, The Netherlands between July 22nd and 26th, 2013. The previous volume to showcase work from the Psychometric Society’s Meeting is New Developments in Quantitative Psychology: Presentations from the 77th Annual Psychometric Society Meeting (Springer, 201...

  18. An Investigation on Elementary School Students' Level of Math Learning, Using Math E-Books (A Case Study: Pishtazan Computer Primary School, 4th Zone of Tehran

    Directory of Open Access Journals (Sweden)

    Arezoo Naseri

    2016-11-01

    Full Text Available Since the focus on technology exists in all schools and classes, teachers need to know how to apply it in their teaching practices. The use of ICT in education is an undeniable necessity. Since the use of information and communication technology can smooth the paths of teaching-learning process for students, the researchers in this study tried to apply one of the information and communication technology tools, called electronic books (E-books in teaching math. The aim of this study is to examine elementary school students' level of math learning, using math e-books with the focus on teaching multiplication (Case Study: Pishtazan computer primary school, the 4th zone of Tehran. Using a quasi-experimental study, 61 third grade students from two primary schools for girls located in the 4th education zone of Tehran were selected. Math tests were used to collect data. Using T-test for independent samples, the results showed that level of math learning was higher in the students who have been trained with the help of e-book, compared to the students who have been trained through traditional teaching method.

  19. Adaptive e-learning methods and IMS Learning Design. An integrated approach

    NARCIS (Netherlands)

    Burgos, Daniel; Specht, Marcus

    2006-01-01

    Please, cite this publication as: Burgos, D., & Specht, M. (2006). Adaptive e-learning methods and IMS Learning Design. In Kinshuk, R. Koper, P. Kommers, P. Kirschner, D. G. Sampson & W. Didderen (Eds.), Proceedings of the 6th IEEE International Conference on Advanced Learning Technologies (pp.

  20. An Analysis of the Relationship between the Learning Process and Learning Motivation Profiles of Japanese Pharmacy Students Using Structural Equation Modeling

    Directory of Open Access Journals (Sweden)

    Shigeo Yamamura

    2018-04-01

    Full Text Available Pharmacy students in Japan have to maintain strong motivation to learn for six years during their education. The authors explored the students’ learning structure. All pharmacy students in their 4th through to 6th year at Josai International University participated in the survey. The revised two factor study process questionnaire and science motivation questionnaire II were used to assess their learning process and learning motivation profiles, respectively. Structural equation modeling (SEM was used to examine a causal relationship between the latent variables in the learning process and those in the learning motivation profile. The learning structure was modeled on the idea that the learning process affects the learning motivation profile of respondents. In the multi-group SEM, the estimated mean of the deep learning to learning motivation profile increased just after their clinical clerkship for 6th year students. This indicated that the clinical experience benefited students’ deep learning, which is probably because the experience of meeting with real patients encourages meaningful learning in pharmacy studies.

  1. The Online Learning Knowledge Garden: A Pedagogic Planning Tool for e-Learning

    NARCIS (Netherlands)

    Scott, Bernard

    2006-01-01

    Please, cite this publication as: Scott, B. (2006). The Online Learning Knowledge Garden: A Pedagogic Planning Tool for e-Learning. Proceedings of International Workshop in Learning Networks for Lifelong Competence Development, TENCompetence Conference. March 30th-31st, Sofia, Bulgaria:

  2. Beagle: an appropriate experimental animal for extrapolating the organ distribution pattern of Th in humans

    International Nuclear Information System (INIS)

    Singh, N.P.; Zimmerman, C.J.; Taylor, G.N.; Wrenn, M.E.

    1988-01-01

    The concentrations and the organ distribution patterns of 228Th, 230Th and 232Th in two 9-y-old dogs of our beagle colony were determined. The dogs were exposed only to background environmental levels of Th isotopes through ingestion (food and water) and inhalation as are humans. The organ distribution patterns of the isotopes in the beagles were compared to the organ distribution patterns in humans to determine if it is appropriate to extrapolate the beagle organ burden data to humans. Among soft tissues, only the lungs, lymph nodes, kidney and liver, and skeleton contained measurable amounts of Th isotopes. The organ distribution pattern of Th isotopes in humans and dog are similar, the majority of Th being in the skeleton of both species. The average skeletal concentrations of 228Th in dogs were 30 to 40 times higher than the average skeletal concentrations of the parent 232Th, whereas the concentration of 228Th in human skeleton was only four to five times higher than 232Th. This suggests that dogs have a higher intake of 228Ra through food than humans. There is a similar trend in the accumulations of 232Th, 230Th and 228Th in the lungs of dog and humans. The percentages of 232Th, 230Th and 228Th in human lungs are 26, 9.7 and 4.8, respectively, compared to 4.2, 2.6 and 0.48, respectively, in dog lungs. The larger percentages of Th isotopes in human lungs may be due simply to the longer life span of humans. If the burdens of Th isotopes in human lungs are normalized to an exposure time of 9.2 y (mean age of dogs at the time of sacrifice), the percent burden of 232Th, 230Th and 228Th in human lungs are estimated to be 3.6, 1.3 and 0.66, respectively. These results suggest that the beagle may be an appropriate experimental animal for extrapolating the organ distribution pattern of Th in humans

  3. The E-learning Cabaret: do's and don'ts in E-Learning Design

    NARCIS (Netherlands)

    Westera, Wim

    2009-01-01

    Westera, W. (2006). The E-Learning Cabaret: do's and don'ts in E-Learning Design. Book of Abstracts, 12th International Conference on Technology Supported Learning & Teaching, Online Educa Berlin (pp. 169-171). November, 29-December, 1, 2006, Berlin, Germany: ICWE-GmbH.

  4. Lifelong Learning: Concept, Policy, Instruments and Implementation

    Directory of Open Access Journals (Sweden)

    Metin TOPRAK

    2012-01-01

    Full Text Available European Union has started an education & training initiative under the umbrella of lifelong learning to achieve the 2020 Agenda targets. Th is initiative has nearly half of a century time horizon, and all designed policies and measures have been consolidated under this initiative. Turkish Education authorities have been monitoring this European eff ort closely and made important legal and institutional regulations in recent couple of years. Th is study examines the primary aspects of lifelong learning in detail: conceptual and philosophical background; recognition strategies; the place of formal, non-formal and informal learning in the lifelong learning approach; financing and measurement ways of lifelong learning; and variety of perspectives of international institutions. In addition, education and training strategy of the Europe’s 2020 vision of lifelong learning is also evaluated in detail. Th e human resources vision of the Europe considers education, occupation and economic activities together to allow authorities to plan the future of the European societies. Th e updating mechanisms of this approach are designed both domestically at national and internationally at European levels. It is concluded, in this study, that the lifelong learning policy and implementation of the Europe should be taken as benchmark.

  5. Speech at the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instruction on Western Medicine Doctors Learning Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhu

    2009-01-01

    @@ Respected leaders, distinguished guests, venerable seniors and comrades, Today, the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instructions on Western Medicine Doctors Learning Traditional Chinese Medicine was inaugurated by the Chinese Association of Integrative Medicine, and it is also an important occasion to review the past and look forward to the future.

  6. Fault plane solutions of the January 26th, 2001 Bhuj earthquake ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    2001-01-26

    Jan 26, 2001 ... The triangles indicate deployment of the eight analog (PS-2) instruments and the rectangles indicate the five digital (Reftek) instruments in the epicentre area. The RPR (Rapar) station is equipped with one analog and one digital instrument. The star indicates the epicentre of the main shock. Fault-plane ...

  7. Exploring Students' Conceptions of Science Learning via Drawing: A Cross-Sectional Analysis

    Science.gov (United States)

    Hsieh, Wen-Min; Tsai, Chin-Chung

    2017-01-01

    This cross-sectional study explored students' conceptions of science learning via drawing analysis. A total of 906 Taiwanese students in 4th, 6th, 8th, 10th, and 12th grade were asked to use drawing to illustrate how they conceptualise science learning. Students' drawings were analysed using a coding checklist to determine the presence or absence…

  8. Validity of Students Worksheet Based Problem-Based Learning for 9th Grade Junior High School in living organism Inheritance and Food Biotechnology.

    Science.gov (United States)

    Jefriadi, J.; Ahda, Y.; Sumarmin, R.

    2018-04-01

    Based on preliminary research of students worksheet used by teachers has several disadvantages such as students worksheet arranged directly drove learners conduct an investigation without preceded by directing learners to a problem or provide stimulation, student's worksheet not provide a concrete imageand presentation activities on the students worksheet not refer to any one learning models curicullum recommended. To address problems Reviews these students then developed a worksheet based on problem-based learning. This is a research development that using Ploom models. The phases are preliminary research, development and assessment. The instruments used in data collection that includes pieces of observation/interviews, instrument self-evaluation, instruments validity. The results of the validation expert on student worksheets get a valid result the average value 80,1%. Validity of students worksheet based problem-based learning for 9th grade junior high school in living organism inheritance and food biotechnology get valid category.

  9. Predicting the Attitudes and Self-Esteem of the Grade 9th Lower Secondary School Students towards Mathematics from Their Perceptions of the Classroom Learning Environment

    Science.gov (United States)

    Tran, Van Dat

    2012-01-01

    This study reports the validity of the hypothesis that students' perceptions of the learning environment of mathematics classroom may predict their attitudes and self-esteem towards mathematics. It examines data from 487 grade 9th students from 14 mathematics classes in 7 Vietnamese lower secondary schools to identify how students' perceptions of…

  10. Technology Enhanced Learning

    NARCIS (Netherlands)

    Klemke, Roland; Specht, Marcus

    2013-01-01

    Klemke, R., & Specht, M. (2013, 26-27 September). Technology Enhanced Learning. Presentation at the fourth international conference on eLearning (eLearning 2013), Belgrade, Serbia. http://econference.metropolitan.ac.rs/

  11. Comparative Analysis of Indicators of Coordination Abilities Development in 5th-7th Graders

    Directory of Open Access Journals (Sweden)

    В. В. Приходько

    2017-09-01

    limbs” by 18.5% and 17.5%, respectively, “Height” by 6.2% (5th-6th grades; “30 m running (s” by 0.2%; “Standing long jump” by 6.9%; “Static equilibrium” by 43.7%; “Tossing rings over a peg” by 17.5% (6th-7th grades; “Standing long jump” by 15.8%, “Pull-ups” by 48.1%, “Evaluation of the ability to differentiate movement speed (accuracy in reproduction of running speed, 90% of maximum” by 26.7%; “Evaluation of static equilibrium by E. Ya. Bondarevsky’s method” by 58.4%; “Height (cm” by 9.7%; “Body weight (kg” by 47.1%. (5th–7th grades.

  12. Using M@th Desktop Notebooks and Palettes in the Classroom

    Science.gov (United States)

    Simonovits, Reinhard

    2011-01-01

    This article explains the didactical design of M@th Desktop (MD), a teaching and learning software application for high schools and universities. The use of two types of MD resources is illustrated: notebooks and palettes, focusing on the topic of exponential functions. The handling of MD in a blended learning approach and the impact on the…

  13. 12th Biennial International Conference on Baroque Music

    Czech Academy of Sciences Publication Activity Database

    Jonášová, Milada; Kapsa, Václav; Maňourová, L.

    2007-01-01

    Roč. 44, č. 1 (2007), s. 91-93 ISSN 0018-7003. [12th Biennial International Conference on Baroque Music . Varšava, 26.07.2006-30.07.2006] R&D Projects: GA AV ČR KJB800580502 Institutional research plan: CEZ:AV0Z90580513 Keywords : music * conference * baroque Subject RIV: AL - Art, Architecture, Cultural Heritage

  14. Workshop on Learning Technology for Education in Cloud

    CERN Document Server

    Rodríguez, Emilio; Santana, Juan; Prieta, Fernando

    2012-01-01

    Learning Technology for Education in Cloud investigates how cloud computing can be used to design applications to support real time on demand learning using technologies. The workshop proceedings provide opportunities for delegates to discuss the latest research in TEL (Technology Enhanced Learning) and its impacts for learners and institutions, using cloud.   The Workshop on Learning Technology for Education in Cloud (LTEC '12) is a forum where researchers, educators and practitioners came together to discuss ideas, projects and lessons learned related to the use of learning technology in cloud, on the 11th-13th July at Salamanca in Spain.

  15. Effects of pre-natal X-ray exposure on learning behaviour of mice

    International Nuclear Information System (INIS)

    Frank, P.; Faber, U.; Budny, T.

    1983-01-01

    The authors investigated whether prenatal X-raying affects the learning behaviour of mice. For this purpose they irradiated mice of strain C57BL/6Ffm with 130 r at different points of the fetal phase. Unirradiated mice served as controls. The animals underwent two learning test series of 14 days each teaching them optical signs. The results of the test series show a distinctly inferior learning ability in the animals exposed to pre-natal irradiation as compared to unirradiated controls. The extent of the reduction of the learning ability depends on the stage of the pregnancy at the time of X-ray exposure. The greatest difference as compared to non-irradiated mice occurred in the animals irradiated at the earliest stage (13th/14th day of pregnancy). The results of the other test groups (15th/16th and 17th/18th day of pregnancy) exhibited less distinct, but still significant differences to the controls. Exposure at the latest period (17th/18th day) coincided with the smallest difference. (orig./MG) [de

  16. 9Th Injury Prevention and Safety Promotion Conference, Melbourne ...

    African Journals Online (AJOL)

    Test

    The 9th Injury Prevention and Safety Promotion Conference was held in Melbourne,. Australia, from 24 to 26 July 2009. This conference formed part of a series of conferences initiated in 1993 by the Monash University's Accident Research Centre (MOARC) in partnership ... outputs in injury presentation work. The speaker ...

  17. The 9th international conference on computing and information technology

    CERN Document Server

    Unger, Herwig; Boonkrong, Sirapat; IC2IT2013

    2013-01-01

    This volume contains the papers of the 9th International Conference on Computing and Information Technology (IC2IT 2013) held at King Mongkut's University of Technology North Bangkok (KMUTNB), Bangkok, Thailand, on May 9th-10th, 2013. Traditionally, the conference is organized in conjunction with the National Conference on Computing and Information Technology, one of the leading Thai national events in the area of Computer Science and Engineering. The conference as well as this volume is structured into 3 main tracks on Data Networks/Communication, Data Mining/Machine Learning, and Human Interfaces/Image processing.  

  18. 14th South African Psychology Congress | Laher | African Safety ...

    African Journals Online (AJOL)

    In response to the xenophobic violence that erupted in South Africa in May 2008, 'Respecting diversity' was an aptly chosen theme for the 14th South African Psychology Congress, held at Emperors Palace in Johannesburg, South Africa from 26 to 29 August 2008. The congress was hosted by the Psychological Society of ...

  19. Reforming the 4th-Year Curriculum as a Springboard to Graduate Medical Training: One School's Experiences and Lessons Learned.

    Science.gov (United States)

    Wackett, Andrew; Daroowalla, Feroza; Lu, Wei-Hsin; Chandran, Latha

    2016-01-01

    Concerns regarding the quality of training in the 4th year of medical school and preparation of graduates to enter residency education persist and are borne out in the literature. We reviewed the published literature regarding Year 4 concerns as well as institutional efforts to improve the 4th-year curriculum from several schools. Based on input from key stakeholders, we established 4 goals for our Year 4 curriculum reform: (a) standardize the curricular structure, (b) allow flexibility and individualization, (c) improve the preparation for residency, and (d) improve student satisfaction. After the reform, we evaluated the outcomes using results from the Association of American Medical Colleges Questionnaire, student focus groups, and program director surveys. This article describes the context, process, and outcomes of the reform of the Year 4 curriculum at Stony Brook University School of Medicine. We were able to achieve all four stated goals for the reform. The significant components of the change included a flexible adaptable curriculum based on individual needs and preferences, standardized learning objectives across the year, standardized competency-based evaluations regardless of discipline, reinforcement of clinical skills, and training for the transition to the workplace as an intern. The reform resulted in increased student satisfaction, increased elective time, and increased preparedness for residency training as perceived by the graduates. The Program Director survey showed significant changes in ability to perform a medical history and exam, management of common medical conditions and emergencies, clinical reasoning and problem-solving skills, working and communication with the healthcare team, and overall professionalism in meeting obligations inherent in the practice of medicine. Lessons learned from our 4th-year reform process are discussed. Listening to the needs of the stakeholders was an important step in ensuring buy-in, having an institutional

  20. Synovial cell production of IL-26 induces bone mineralization in spondyloarthritis

    DEFF Research Database (Denmark)

    Heftdal, Line Dam; Andersen, Thomas; Jæhger, Ditte

    2017-01-01

    expression in SpA patients, and examine the in vitro production of IL-26 by synovial cells and the effects of IL-26 on human osteoblasts. IL-26 was measured by ELISA in plasma and synovial fluid (SF) of 15 SpA patients and in plasma samples from 12 healthy controls. Facet joints from axial SpA patients were...... and the myofibroblast marker α-smooth-muscle-actin (αSMA) and analyzed by flow cytometry. Human osteoblasts were cultured in the presence of IL-26, and the degree of mineralization was quantified. We found that IL-26 levels in SF were increased compared with plasma (P ... in facet joints of axial SpA patients within the bone marrow. IL-26 secretion was primarily found in αSMA(+) myofibroblasts. In contrast, Th17 cells did not produce detectable amounts of IL-26. Human osteoblasts treated with IL-26 showed increased mineralization compared with untreated osteoblasts (P = 0...

  1. 4th International Cryocoolers Conference

    CERN Document Server

    Patton, George; Knox, Margaret

    1987-01-01

    The Cryocoolers 4 proceedings archives the contributions of leading international experts at the 4th International Cryocooler Conference that was held in Easton, Maryland on September 25-26, 1986. About 170 people attended the conference representing 11 countries, 14 universities, 21 government laboratories and 60 industrial companies. Thirty-one papers were presented describing advancements and applications of cryocoolers in the temperature range below 80K. This year's conference was sponsored by the David Taylor Naval Ship Research and Development Center of Annapolis, Maryland, and the conference proceedings reproduced here was published by them.

  2. Methodologies and intelligent systems for technology enhanced learning

    CERN Document Server

    Gennari, Rosella; Vitorini, Pierpaolo; Vicari, Rosa; Prieta, Fernando

    2014-01-01

    This volume presents recent research on Methodologies and Intelligent Systems for Technology Enhanced Learning. It contains the contributions of ebuTEL 2013 conference which took place in Trento, Italy, on September, 16th 2013 and of mis4TEL 2014 conference, which took take place in Salamanca, Spain, on September, 4th-6th 2014 This conference series are an open forum for discussing intelligent systems for Technology Enhanced Learning and empirical methodologies for its design or evaluation.

  3. Distribution of U and Th in Growth Zones of Manganese Nodules

    DEFF Research Database (Denmark)

    Kunzendorf, Helmar; Friedrich, G. H. W.

    1976-01-01

    Growth zones and individual sublayers from one manganese nodule and three manganese crusts from an area south of Hawaii were analysed for U and Th by the delayed-neutron counting technique. The concentrations of uranium and thorium in the manganese nodule are highest in the outermost zone on top...... to the sediment which has low concentrations of Fe, relative to the zone last exposed to sea water, has also low U contents (2.7 ppm). Th concentrations are higher in the outermost zone on top of the nodule (40 to a maximum of 130 ppm) than in the zone last exposed to the sediment (about 20 ppm Th). Manganese...... crusts contain up to 9 ppm U in the outermost zones last exposed to the sea water. They also have higher concentrations of Th (up to 64 ppm) relative to the inner zones of the crust growing on altered andesitic rock, which contains about 8 ppm U and about 26 ppm Th as an average....

  4. PREFACE: 8th International Symposium of the Digital Earth (ISDE8)

    Science.gov (United States)

    2014-02-01

    Proceedings of the 8th International Symposium of Digital Earth (8th ISDE) 2013 Kuching, Sarawak, Malaysia, 26th-29th August, 2013 Conference logo This proceedings consists of the peer-reviewed papers from 8th International Symposium for Digital Earth (ISDE) held in Kuching, Sarawak, Malaysia during 26th-29th August, 2013. The 8th ISDE was a successful event in the Symposium Series of the International Society of Digital Earth, that was previously held in China (1999), Canada (2001), Czech Republic (2003), Japan (2005), the United States (2007), China (2009), and Australia (2011). The 8th ISDE, with the theme 'Transforming Knowledge into Sustainable Practice' aims to enable digital earth scientists, experts and professionals related to the field of geospatial science and technology to provide a brand new opportunity to share their ideas and insights on how we share knowledge and act together globally. In addition, the ISDE symposium series has been providing a venue for researchers and industry practitioners to discuss new ideas, collaborate to solve complex solutions to various complex problems, and importantly, pave new ways in digital earth environment. This 8th ISDE included 20 technical sessions, workshops and student sessions in various areas of digital earth; ranging from digital earth vision & innovation; earth observation technologies; ICT technologies (including spatial data infrastructures); empowering the community and engaging society; applications and innovation of digital earth for environmental applications such as hazard, pollution, flood, air quality, disaster and health, biodiversity, sustainability, forestry, early warning and emergency management, national security, natural resource management and agriculture; mining, energy and resources development; transformation towards sustainable low carbon society; digital city and green cities: towards urban sustainability; and managing water environment for sustainable development. The success of the 8

  5. Th17 cells in the pathogenesis of multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Marek Juszczak

    2009-10-01

    Full Text Available Th17 cells are a recently described subset of T helper lymphocytes characterized by the production of IL-17 (IL-17A. Since their discovery in 2003, studies on Th17 cells have become increasingly popular among immunologists and they have emerged as key players in the pathogenesis of multiple sclerosis (MS and other autoimmune disorders traditionally attributed to Th1 cells. Murine Th17 lymphocytes differentiate from naive CD4 cells in a specific cytokine environment, which includes TGF- and IL-6 or IL-21, whereas human Th17 cell development requires TGF-, IL-1, and IL-2 in combination with IL-6, IL-21, or IL-23. Th17-related response is additionally enhanced by osteopontin, TNF, and PGE2 and suppressed by IL-25, IL-27, IL-35, and IL-10. Apart from their main cytokine, Th17 cells can also express IL-17F, IL-21, IL-22, TNF, CCL20, and, in humans, IL-26. All of these mediators may contribute to the proinflammatory action of Th17 .cells both in the clearance of various pathogens and in autoimmunity. At least some of these functions are exerted through the induction of neutrophil-recruiting chemokines (CXCL1, CXCL2, CXCL8 by IL-17. Accumulating evidence from studies on mice and humans indicates an important role of Th17 cells in mediating autoimmune neuroinflammation. This has led some immunologists to question the previously exhibited importance of Th1 cells in MS pathology. However, more recent data suggest that both these T-cell subsets are capable of inducing and promoting the disease. Further investigation is required to clarify the role of Th17 cells in the pathogenesis of MS since some of the Th17-related molecules appear as attractive targets for future therapeutic strategies

  6. Far IR spectra of Th(IV) halide complexes of some heterocyclic bases

    International Nuclear Information System (INIS)

    Srivastava, A.K.; Agarwal, R.K.; Srivastava, M.; Kapoor, V.; Srivastava, T.N.

    1981-01-01

    The synthesis and IR spectra of Th(IV) perchlorato, nitrato and thiocyanato complexes of some heterocyclic bases have been reported. Halogens are common ligands in coordination chemistry forming coordinate bonds with metals readily. Metal halogen (M-X) stretching bands show a strong absorption in the far-IR region. Very little information is available on Th-X stretching frequencies. In the present communication, adducts of Th(IV) halide with certain nitrogen heterocyclic bases such as pyridine, α-picoline, 2-amino pyridine, 2:4-lutidine, 2:6-lutidine, quinoline, 2,2'-bipyridine and 1,10-phenanthroline were synthesised and characterised. Experimental details are given. Results are presented and discussed. (author)

  7. Structuring mobile and contextual learning

    NARCIS (Netherlands)

    Glahn, Christian; Specht, Marcus

    2011-01-01

    Glahn, C., & Specht, M. (2011). Structuring mobile and contextual learning. In Proceedings of the 10th World Conference on Mobile and Contextual Learning (pp. 188-195). October, 18-21, 2011, Beijing, China.

  8. HASL measurements of fallout following the September 26, 1976 Chinese nuclear test

    International Nuclear Information System (INIS)

    1976-10-01

    Results are reported from measurements of radioactivity in the fallout from the nuclear test conducted by the Peoples Republic of China on September 26th, 1976. These measurements were carried on through Monday, October 18th. Results of these measurements made in New York and New Jersey, including external radiation exposure, air concentrations, deposition and the concentration of radioiodine in milk, are reported. An estimate of the thyroid dose from milk consumption is also included

  9. Summary of the workshop on HOM in SPL, held at CERN June 25-26.

    CERN Document Server

    Lombardi, A; Weingarten, W

    2009-01-01

    A mini-workshop on the subject of HOMs in a superconducting proton linac was held at CERN on the 25th and 26th June 2009. The purpose of this workshop was to discuss more specifically the effects of HOMs on beam dynamics in the SPL and comparable accelerators and to provide guidelines for the specification of HOM dampers, if necessary.

  10. Whirlwind Drama During Spirit's 496th Sol

    Science.gov (United States)

    2005-01-01

    This movie clip shows a dust devil growing in size and blowing across the plain inside Mars' Gusev Crater. The clip consists of frames taken by the navigation camera on NASA's Mars Exploration Rover Spirit during the morning of the rover's 496th martian day, or sol (May 26, 2005). Contrast has been enhanced for anything in the images that changes from frame to frame, that is, for the dust moved by wind.

  11. Public health and social supervision issues within public administration of ukrainian territories in the late 8th- early 9th centuries.

    Science.gov (United States)

    Hrynzovskyi, Anatolii M; Holovanova, Irina A; Omelchuk, Sergei T; Kuzminska, Olena V; Hrynzovska, Anastasia A; Karlova, Olena O; Kondratiuk, Vitalii Ye

    Introduction: The public health system modernization history is based upon the progress in state country administration and administration of healthcare within the sectorwide approach. The WHO European Bureau pays much attention to the National Health Service systems development while implementing their basic policies. The Ukrainian state health service management was founded basing on the regulatory field of the Russian Empire, using the European healthcare promotion experience. Aim: of the article is the analysis of the regulatory field of police and amenity authorities of the Russian Empire and Ukraine within the medical and social service in the 18th-19th centuries. Materials and methods: The structure of the article corresponds to the problem city and chronology principles, using the following methods and techniques of scientific learning: the systemic, historic, regulatory comparative, logical and structural-functional analysis of the studied medical-legal phenomena. The study sources are the scientific publications, collections of laws and executive orders of the Russian Empire and Ukraine in the 18th-19th centuries. Review: As a result of the performed work it can be determined were the main directions of the police competence in late 18th- early 19th centuries. Conclusion: Preserving health, treatment of the ill and injured, management of medical and social service of those in need, holding various preventive activities and supporting safe environment and regulating the safety of food were the main directions of the police competence in late 18th- early 19th centuries.

  12. The PATT 26 conference Stockholm, Sweden 26–30 June 2012 : Technology Education in the 21st Century

    OpenAIRE

    2012-01-01

    PATT 26 will be held at the Royal Institute of Technology (KTH) in Stockholm, the beautiful capital of Sweden. The PATT 26 conference is part of a two-conference arrangement organized by the Royal Institute of Technology and the Centre for School Technology Education, CETIS, Linköping University, under the common heading Technology Education in the 21st Century. We hereby welcome international colleagues to this golden opportunity to share and learn more about the latest on-going and complete...

  13. The Effect of Blended Learning and Social Media-Supported Learning on the Students' Attitude and Self-Directed Learning Skills in Science Education

    Science.gov (United States)

    Akgunduz, Devrim; Akinoglu, Orhan

    2016-01-01

    The main purpose of this study is to investigate the effect of blended learning and social media supported learning on the students' attitude and self-directed learning skills in Science Education. This research took place with the 7th grade 74 students attending to a primary school in Kadikoy, Istanbul and carried out "Our Body Systems"…

  14. Lifelong Learning in Colombia and Denmark

    DEFF Research Database (Denmark)

    Olesen, Henning Salling

    2004-01-01

    The article examines education and learning opportunities in Colombia against the backdrop of Danish modernisation and reform experiences from second half of 20th Century. The article discusses possibilities to learn from Danish experiences in the development of a Colombian lifelong learning policy...

  15. Learning Perl Student Workbook

    CERN Document Server

    foy, brian

    2012-01-01

    This is an ebook-only workbook to accompany the 6th Edition of Learning Perl ("the Llama"). If you're just getting started with Perl, this is the book you want-whether you're a programmer, system administrator, or web hacker. This 6th edition of Learning Perl covers recent changes to the language up to version 5.14. Exercises are presented in the first half of the workbook, with the answers in the second. Topics include: Scalar DataLists and ArraysSubroutinesInput and OutputHashesIn the World of Regular ExpressionsMatching with Regular ExpressionsProcessing Text with Regular Expressions10.

  16. 6th International Symposium on Ambient Intelligence

    CERN Document Server

    Novais, Paulo; Pereira, António; González, Gabriel; Fernández-Caballero, Antonio

    2015-01-01

    This volume contains the proceedings of the 6th International Symposium on Ambient Intelligence (ISAmI 2015), held in Salamanca, Spain on June 3th-5th at the University of Salamanca. After a careful review, 27 papers from 10 different countries were selected to be presented in ISAmI 2015 at the conference and published in the proceedings.  ISAmI has been running annually and aiming to bring together researchers from various disciplines that constitute the scientific field of Ambient Intelligence to present and discuss the latest results, new ideas, projects and lessons learned, namely in terms of software and applications, and aims to bring together researchers from various disciplines that are interested in all aspects of this area. Ambient Intelligence is a recent paradigm emerging from Artificial Intelligence, where computers are used as proactive tools assisting people with their day-to-day activities, making everyone’s life more comfortable. Another main concern of AmI originates from the human comput...

  17. Th isotopes in the Santa Monica basin: temporal variation, long-term mass balance and model rate constants

    International Nuclear Information System (INIS)

    Huh, Chih-An

    1995-01-01

    Distribution and flux of 234 Th, 232 Th and 230 Th in the water column of central Santa Monica basin observed over a period of seven years show seasonal and interannual variabilities. A steady-state model is applied to the integrated data to calculate long term average flux and model rate constants of Th isotopes. Mass balance calculations show that the basin acts like a closed system for short-lived 234 Th, but not for the long-lived isotopes 230 Th and 232 Th. Most 230 Th in the basin is transported from elsewhere. Of the incoming Th, 40-55% of the 230 Th and 14-26% of the 232 Th enter the surface water in dissolved form. In the upper 100m, the residence time of dissolved Th with respect to adsorption onto suspended particulates, 70-80 days, is about one order of magnitude higher than the residence time of suspended particles with respect to aggregation into sinking particles, 7-10 days. (author)

  18. The 5th National Logistics and Supply Chain Conference

    OpenAIRE

    PEKER, İskender

    2016-01-01

    Abstract. The 5thNational Logistics and Supply Chain Conference (ULTZK) held in Mersin Divan Hotel on the 26-28 May 2016. A number of academics, logistics service receiver company representatives (manufacturers, wholesalers, retailers, etc.), logistics service provider company representatives (transport, logistics, storage, etc.), non-governmental organization representatives, and the relevant public institution and organization representatives participated to the conducted panels and session...

  19. CLIMA 2016 - proceedings of the 12th REHVA World Congress:volume 6

    OpenAIRE

    2016-01-01

    CLIMA 2016, 12th REHVA World Congress 2016 in Aalborg north of Denmark. Full reviewed papers presented at CLIMA 2016 is published in the conference proceedings. This volume contains the sessions number 24 + 25 +26 + 27 + 28 +29 + 30 from track "Building Performance".

  20. Enhancing learning with technology

    NARCIS (Netherlands)

    Specht, Marcus; Klemke, Roland

    2013-01-01

    Specht, M., & Klemke, R. (2013, 26-27 September). Enhancing Learning with Technology. In D. Milosevic (Ed.), Proceedings of the fourth international conference on eLearning (eLearning 2013) (pp. 37-45). Belgrade Metropolitan University, Belgrade, Serbia. http://econference.metropolitan.ac.rs/

  1. The results of STEM education methods in physics at the 11th grade level: Light and visual equipment lesson

    Science.gov (United States)

    Tungsombatsanti, A.; Ponkham, K.; Somtoa, T.

    2018-01-01

    This research aimed to: 1) To evaluate the efficiency of the process and the efficiency of the results (E1 / E2) of the innovative instructional lesson plan in the form of the STEM Education method in the field of physics of secondary students at the 10th grade level in physics class to determine the efficiency of the STEM based on criteria of the 70/70 standard level. 2) To study students' critical thinking skills of secondary students at the 11th grade level, and assessing skill in criteria 80 percentage 3) To compare learning achievements between students' pre-post testing after taught in STEM Education 4) To evaluate Student' Satisfaction after using STEM Education teaching by using mean compare to 5 points Likert Scale. The participant used were 40 students from grade 11 at Borabu School, Borabu District, Mahasarakham Province, semester 2, Academic year 2016. Tools used in this study consist of: 1) STEM Education plan about the force and laws of motion for grade 11 students of 1 schemes with total of 15 hours, 2) The test of critical think skills with essay type in amount of 30 items, 3) achievement test on Light and visual equipment with multiple-choice of 4 options of 30 items, 4) satisfaction learning with 5 Rating Scale of 16 items. The statistics used in data analysis were percentage, mean, standard deviation, and t-test (Dependent). The results showed that 1) The results of these findings revealed that the efficiency of the STEM based on criteria indicate that are higher than the standard level of the 70/70 at 71.51/75 2) Student has critical thinking scores that are higher than criteria 80 percentage as amount is 26 people. 3) Statistically significant of students' learning achievements to their later outcomes were differentiated between pretest and posttest at the .05 level, evidently. 4) The student' level of satisfaction toward the learning by using STEM Education plan was at a good level (X ¯ = 4.33, S.D = 0.64).

  2. Elevated Levels of Cytokines Associated with Th2 and Th17 Cells in Vitreous Fluid of Proliferative Diabetic Retinopathy Patients.

    Directory of Open Access Journals (Sweden)

    Masaru Takeuchi

    Full Text Available Macrophages are involved in low-grade inflammation in diabetes, and play pathogenic roles in proliferative diabetic retinopathy (PDR by producing proinflammatory cytokines. T cells as well as other cells are also activated by proinflammatory cytokines, and infiltration into the vitreous of patients with PDR has been shown. In this study, we measured helper T (Th cell-related cytokines in the vitreous of PDR patients to define the characteristics of Th-mediated immune responses associated with PDR. The study group consisted of 25 type 2 diabetic patients (25 eyes with PDR. The control group consisted of 27 patients with epiretinal membrane (ERM, 26 patients with idiopathic macular hole (MH, and 26 patients with uveitis associated with sarcoidosis. Vitreous fluid was obtained at the beginning of vitrectomy, and centrifuging for cellular removals was not performed. Serum was also collected from PDR patients. IL-1β, IL-4, IL-6, IL-10, IL-17A, IL-17F, IL-21, IL-22, IL-23, IL-25, IL-31, IL-33, IFN-γ, soluble sCD40L, and TNFα in the vitreous and serum samples were measured. Both percent detectable and levels of IL-4, IL-6, IL-17A, IL-21, IL-22, and TNFα in the vitreous were significantly higher than those in the serum in PDR patients. Vitreous levels of these cytokines and IL-31 were significantly higher in PDR than in ERM or MH patients. Vitreous levels of IL-4, IL-17A, IL-22, IL-31, and TNFα in PDR patients were also significantly higher than those of sarcoidosis patients. In PDR patients, vitreous IL-17A level correlated significantly with vitreous levels of IL-22 and IL-31, and especially with IL-4 and TNFα. Although it is unclear whether these cytokines play facilitative roles or inhibitory roles for the progression of PDR, the present study indicated that Th2- and Th17-related immune responses are involved in the pathogenesis of PDR.

  3. Essential fats for future health. Proceedings of the 9th Unilever Nutrition Symposium, 26-27 May 2010.

    Science.gov (United States)

    Calder, P C; Dangour, A D; Diekman, C; Eilander, A; Koletzko, B; Meijer, G W; Mozaffarian, D; Niinikoski, H; Osendarp, S J M; Pietinen, P; Schuit, J; Uauy, R

    2010-12-01

    The 9th Unilever Nutrition Symposium entitled 'Essential fats for future health', held on 26-27 May 2010, aimed to review the dietary recommendations for essential fatty acids (EFA); discuss the scientific evidence for the roles of EFA in cognition, immune function and cardiovascular health; and to identify opportunities for joint efforts by industry, academia, governmental and non-governmental organizations to effectively improve health behaviour. This paper summarizes the main conclusions of the presentations given at the symposium. Linoleic acid (LA) and α-linolenic acid (ALA) are EFA that cannot by synthesized by the human body. Docosahexaenoic acid (DHA) is considered as conditionally essential because of its limited formation from ALA in the human body and its critical role in early normal retinal and brain development and, jointly with eicosapentaenoic acid (EPA), in prevention of cardiovascular disease (CVD). Some evidence for possible beneficial roles of n-3 fatty acids for immune function and adult cognitive function is emerging. A higher consumption of polyunsaturated fatty acids (PUFA; >10%E), including LA, ALA and at least 250-500 mg per day of EPA+DHA, is recommended for prevention of coronary heart disease (CHD). Two dietary interventions suggest that EFA may affect CVD risk factors in children similarly as in adults. To ensure an adequate EFA intake of the population, including children, public health authorities should develop clear messages based on current science; ensure availability of healthy, palatable foods; and collaborate with scientists, the food industry, schools, hospitals, health-care providers and communities to encourage consumers to make healthy choices.

  4. Quadrennial Review of Military Compensation (6th). Executive Summary. Volumes 1 thru 1C, and Volumes 2 thru 3

    Science.gov (United States)

    1988-08-01

    CIVILIAN EARNINGS PROFILE: ENLISTED SOURCE: SYLLOGISTICS 2-24 6th ORNC Esport -Volum 11 participation and higher than that of civilian counterparts in...7-26 6th QRNC esport - Volume I m Eliminate the existing 80 percent limiltation onmeai/entertairment deductions incurred in connection with the

  5. The integrated learning management using the STEM education for improve learning achievement and creativity in the topic of force and motion at the 9th grade level

    Science.gov (United States)

    Kakarndee, Nampetch; Kudthalang, Nukool; Jansawang, Natchanok

    2018-01-01

    The aims of this research study were to investigate and analyze the processing performances and the performance results (E1/E2) efficiency at the determining criteria for planning students' improvements to their learning processes toward their scientific knowledge were investigated, carry out the investigations, gathering evidence, and proposing explanations were developed and predicted. Students' engagements to their needs in unambiguous and clearly content of science teaching onto the instructional processes were attempted for establishing a national approach with the STEM education instructional method were strategized. Research administrations were designed to a sample size consisted of 40 secondary students in science class at the 9th grade level in Borabu School with the purposive sampling technique was selected. Using the STEM Education instructional innovation's lesson plans were managed learning activities. Students' learning achievements were assessed with the Pre-Test and Post-Test designs of 30 items. Students' creative thinking abilities were determined of their perceptions that obtained of the 3-item Creative Thinking Ability Test. The results for the effectiveness of the innovative instructional lesson plans based on the STEM Education Method, the lessoning effectiveness (E1/E2) evidences of 78.95/76.58 over the threshold setting is 75/75. Pretest-posttest designs for assessing students' learning achievements that impact a student's ability to achieve and explains with the STEM education instructional method were differences, significantly (ρ<.001) and the posttest of the 3-item Creative Thinking Ability Test designs for assessing Students' creative thinking abilities that impact a student's ability to have a good skill level in originality, fluency and flexibility thinking with the STEM education instructional method were differences, significantly (ρ<.001).

  6. E-Learning and Role of World Wide Web in E-Learning

    OpenAIRE

    Jahankhani, Hossein

    2012-01-01

    This paper reviews some of the aspects of the E-learning through the World Wide Web. E-revolution as new phenomenon influenced the society by its means and strategies. E-learning is one of the sub-products of E-revolution, towards making more convenient and effective learning. In time Internet become a source of information, people start to learn through the Internet instead of books. It gives the flexibility to remote access at any time. The working people and the students are inspired by th...

  7. Meeting Report: International nephrology days - In honor of the 75(th) anniversary of acad. Momir Polenakovic and 50 years of scientific work, 26-27 September 2014.

    Science.gov (United States)

    Spasovski, G

    2015-01-01

    The International Nephrology Days in honor of the 75(th) anniversary of Academician Momir Polenakovic and 50 years of his scientific work were held in the Macedonian Academy of Sciences and Arts (MASA) on 26 and 27 September 2014. Organizers of the meeting were the Macedonian Academy of Sciences and Arts and the Macedonian Society of Nephrology, Dialysis, Transplantation and Artificial Organs (MSNDTAO). The days were programmed with the VII Macedonian-Croatian Nephrology Meeting and the Continuing Medical Education (CME) Course on "Renal Replacement Therapy - when & how - update on the outcome and cost-efficacy" organized by the MSNDTAO in cooperation with the European Renal Association (ERA-EDTA). Prominent academicians, researchers and nephrologists from Europe and neighboring countries contributed with their lectures and discussion at this scientific event. On September 26, 2014 the opening talk was given by Acad. V. Kambovski, President of the MASA, about the Life and Work of Academician Momir Polenakovic. In honor of his anniversary and valuable scientific opus, during the meeting Acad. Momir Polenakovic was awarded with Certificate of the European Renal Association (ERA-EDTA) for his significant role in the development of nephrology in the Balkan region and couple of other diplomas and acknowledgement. Prof. Polenakovic is founder of the MSNDTAO and his lifetime honorary president.

  8. Scientific conference on the occasion of the 200th anniversary of the foundation of the Kraków Learned Society (in Polish

    Directory of Open Access Journals (Sweden)

    Tomasz Pudłocki

    2016-11-01

    Full Text Available The author submittedto print the report of the scientific conference which had been organized on the occasion of the 200th anniversary of the foundation of the Kraków Learned Society. The session was held in December 9–10, 2015 as a result of cooperation between the Polish Academy of Arts and Sciences, the Jagiellonian University as well as the Scientific Archives of the Polish Academy of Sciences and the Polish Academy of Arts and Sciences in Kraków. It brought an international group of speakers together to discuss in their deliberations the various aspects of the Cracow Learned Society. The outcome of the meeting is the publication Towarzystwo Naukowe Krakowskie w 200-lecie założenia (1815–2015. Materiały konferencji naukowej 9–10 grudnia 2015, edited by Wanda Lohman (Kraków, 2016.

  9. Development of Scientific Approach Based on Discovery Learning Module

    Science.gov (United States)

    Ellizar, E.; Hardeli, H.; Beltris, S.; Suharni, R.

    2018-04-01

    Scientific Approach is a learning process, designed to make the students actively construct their own knowledge through stages of scientific method. The scientific approach in learning process can be done by using learning modules. One of the learning model is discovery based learning. Discovery learning is a learning model for the valuable things in learning through various activities, such as observation, experience, and reasoning. In fact, the students’ activity to construct their own knowledge were not optimal. It’s because the available learning modules were not in line with the scientific approach. The purpose of this study was to develop a scientific approach discovery based learning module on Acid Based, also on electrolyte and non-electrolyte solution. The developing process of this chemistry modules use the Plomp Model with three main stages. The stages are preliminary research, prototyping stage, and the assessment stage. The subject of this research was the 10th and 11th Grade of Senior High School students (SMAN 2 Padang). Validation were tested by the experts of Chemistry lecturers and teachers. Practicality of these modules had been tested through questionnaire. The effectiveness had been tested through experimental procedure by comparing student achievement between experiment and control groups. Based on the findings, it can be concluded that the developed scientific approach discovery based learning module significantly improve the students’ learning in Acid-based and Electrolyte solution. The result of the data analysis indicated that the chemistry module was valid in content, construct, and presentation. Chemistry module also has a good practicality level and also accordance with the available time. This chemistry module was also effective, because it can help the students to understand the content of the learning material. That’s proved by the result of learning student. Based on the result can conclude that chemistry module based on

  10. Determination of the activity concentration of 230Th in phosphoric acids produced in Brazil

    International Nuclear Information System (INIS)

    Taddei, M.H.T.; Ferreira, M.T.; Fukuma, H.T.; Xavier, T.T.; Sousa, F.V.T.S.

    2017-01-01

    The high uranium phosphate rock from Itataia, Brazil, was processed using the wet route in the dihydrate system to manufacture phosphoric acid. The uranium contained in phosphoric acid was recovered by the solvent extraction technique. The distribution of the long half-life radionuclides from the decay series of 238 U and 232 Th were evaluated in these processes. The 26 Ra, 228 Ra and 210 Pb radionuclides were found predominantly in phosphogypsum, while the isotopes of 228 Th, 230 Th and 232 Th predominated in phosphoric acid after extracting uranium. The main concern in the commercialization of phosphoric acid that will be produced in the Itataia plant is in relation to the content of 230 Th. This work determined the content of these radionuclides in phosphoric acid from different locations in the country in order to compare

  11. 26th May 2011 -Delegate to CERN Open Council sessions and European Commission Head of Unit for Joint Programming European Research Area, DG Research and Innovation R. Lečbychová visiting the CERN Control Centre with M. Pojer, accompanied by CERN S. Stavrev.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    26th May 2011 -Delegate to CERN Open Council sessions and European Commission Head of Unit for Joint Programming European Research Area, DG Research and Innovation R. Lečbychová visiting the CERN Control Centre with M. Pojer, accompanied by CERN S. Stavrev.

  12. 26th August 2010 - World Meteorological Organization Secretary-General M. Jarraud signing the guest book with CERN Director-General R. Heuer and visiting the LHC superconducting magnet test hall with Technology Department Head F. Bordry; throughout accompanied by M. Bona, CERN Relations with International Organisations

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    26th August 2010 - World Meteorological Organization Secretary-General M. Jarraud signing the guest book with CERN Director-General R. Heuer and visiting the LHC superconducting magnet test hall with Technology Department Head F. Bordry; throughout accompanied by M. Bona, CERN Relations with International Organisations

  13. Delayed Activation Kinetics of Th2- and Th17 Cells Compared to Th1 Cells.

    Science.gov (United States)

    Duechting, Andrea; Przybyla, Anna; Kuerten, Stefanie; Lehmann, Paul V

    2017-09-12

    During immune responses, different classes of T cells arise: Th1, Th2, and Th17. Mobilizing the right class plays a critical role in successful host defense and therefore defining the ratios of Th1/Th2/Th17 cells within the antigen-specific T cell repertoire is critical for immune monitoring purposes. Antigen-specific Th1, Th2, and Th17 cells can be detected by challenging peripheral blood mononuclear cells (PBMC) with antigen, and establishing the numbers of T cells producing the respective lead cytokine, IFN-γ and IL-2 for Th1 cells, IL-4 and IL-5 for Th2, and IL-17 for Th-17 cells, respectively. Traditionally, these cytokines are measured within 6 h in flow cytometry. We show here that 6 h of stimulation is sufficient to detect peptide-induced production of IFN-γ, but 24 h are required to reveal the full frequency of protein antigen-specific Th1 cells. Also the detection of IL-2 producing Th1 cells requires 24 h stimulation cultures. Measurements of IL-4 producing Th2 cells requires 48-h cultures and 96 h are required for frequency measurements of IL-5 and IL-17 secreting T cells. Therefore, accounting for the differential secretion kinetics of these cytokines is critical for the accurate determination of the frequencies and ratios of antigen-specific Th1, Th2, and Th17 cells.

  14. Th1-, Th2-, and Th17-associated cytokine expression in hypopharyngeal carcinoma and clinical significance.

    Science.gov (United States)

    Chen, Xuemei; Wang, Junfu; Wang, Rui; Su, Qinghong; Luan, Junwen; Huang, Haiyan; Zhou, Peng; Liu, Jinsheng; Xu, Xiaoqun

    2016-02-01

    Th0 cells differentiate into Th1 or Th2 depending on multiple transcription factors acting on specific time points to regulate gene expression. Th17 cells, a subset of IL-17-producing T cells distinct from Th1 or Th2 cells, have been described as key players in inflammation and autoimmune diseases as well as cancer development. In the present study, 53 patients with hypopharyngeal cancer were included. The expression levels of Th1-, Th2- and Th17-associated cytokines in hypopharyngeal cancer tissues and pericarcinoma tissues were detected. The relationship between Th1, Th2, or Th17 infiltration and metastasis was studied. Our results showed that the mRNA and protein expressions of Th1 cytokines were lower, while the expressions of Th2 and Th17 cytokines were higher in tumor tissues, and the intensity of expression was strengthened with clinical stage increasing. Cancer tissues had higher level expressions of Th2 and Th17 cytokines than that of pericarcinoma tissues. From the above data, we speculated that high expressions of Th2- and Th17-associated cytokines in hypopharyngeal carcinoma may contribute to cancer development and metastasis.

  15. Learning from prescribing errors

    OpenAIRE

    Dean, B

    2002-01-01

    

 The importance of learning from medical error has recently received increasing emphasis. This paper focuses on prescribing errors and argues that, while learning from prescribing errors is a laudable goal, there are currently barriers that can prevent this occurring. Learning from errors can take place on an individual level, at a team level, and across an organisation. Barriers to learning from prescribing errors include the non-discovery of many prescribing errors, lack of feedback to th...

  16. Design Fixation and Cooperative Learning in Elementary Engineering Design Project: A Case Study

    Science.gov (United States)

    Luo, Yi

    2015-01-01

    This paper presents a case study examining 3rd, 4th and 5th graders' design fixation and cooperative learning in an engineering design project. A mixed methods instrument, the Cooperative Learning Observation Protocol (CLOP), was adapted to record frequency and class observation on cooperative learning engagement through detailed field notes.…

  17. French school of neurology in the 19 th and first half of the 20th century, and its influence in Brazil

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2013-10-01

    Full Text Available French medicine was of the utmost importance for the birth of modern medicine and neurology in the 19 th century. Innovative approaches, such as examination at the bedside, the use of the stethoscope, techniques of auscultation, palpation, and close patient examination, besides emphasis on anatomical-clinical correlation and observation of the outcome of the disease, were put into practice. French medicine offered professional training and incentives for the beginnings of Brazilian neurology and psychiatry. Returning from France, many Brazilian physicians implemented what they had learned, mainly in Paris. The most important pupils of the French neurology schools in Brazil during the 19 th century and first half of the 20 th century include names like Antonio Austregesilo, Aloysio de Castro, Enjolras Vampré, and Deolindo Couto, founders of the leading Brazilian neurological schools, directly influenced by Dejerine, Pierre Marie, Guillain and Babinski.

  18. Electronic Learning. Art: The 4th "R."

    Science.gov (United States)

    Ohler, Jason

    2001-01-01

    With the Internet revolution in education, students are learning to think as designers and artists. The language of art must become the fourth "R," and students must become literate in this environment. The paper discusses art and the digital age and what teachers can do (rename art, hire more art teachers, and increase fourth-R literacy…

  19. Gamma Spectrometric Determination of U, Th, K and Some Geochemical Applications

    International Nuclear Information System (INIS)

    Dodona, A.; Tashko, A.

    2001-01-01

    The application of 'in situ' gamma-spectrometric method (''infinite'' environment), made possible the simultanious determination of U, Th and K. 4 channel gamma-spectrometric analyser with NaI(TI) scintilation counter crystal detector (103 cm 3 φ=50x50mm) was used to determin U, Th(more than 1-2 ppm) and K (more than 1%) in laboratory conditions. The detector was inserted into a lead camera and calibrated for measurement geometry with vessel of ''Marineli'' type of a 17o cm 3 volume. The study of main factors, which influence in the gamma spectrometric measurements, (the technical, physical, geometrical and time parameters) has been carried out. International standards of U, Th, K and internal monitoring standard samples are used for the calibration. External analytical control has been realized by other radiometric and chemical methods. The detection limits ( 1 ppm Th, 2ppm U and 1% K) and the relative errors (17-20% for 1-10 ppm U, Th and 10-15% for more than 10 ppm U, Th and more than 1% K) guarantee a quantitative analysis that may be used successfully in the geochemical studies. Some geochemical applications, based on the content of Th, U and Th/U ratio in rocks samples that we have we have analyzed with this method, are shown in this paper. U, Th and their ratio are used as trace elements to indicate the differences between the acidic magmatic rocks of Albania (Th/U ratio=2-6 and>10). The bimodal character of Th/U scattering in ignimbrides and monzonites (Korabi zone) shows that in addition to the ''normal'' rocks, there are also some ones enriched with Th, So, the differential analysis of Th, U, and K may be used as geochemical exploration criteria for the radioactive and non-radioactive mineralization, such as REE (Rare Earth Elements), phospghorites, bauxites, placers etc. (authors)

  20. The Effect of Learning Cycle Model on Students’ Reducing Ecological Footprints

    Directory of Open Access Journals (Sweden)

    Özgül Keleş

    2011-12-01

    Full Text Available The objective of this study is to investigate effect of ecological footprint education, in which 5E learning cycle model is used, in reducing primary school students’ ecological footprints. The working group of the study is composed of 124 primary school students studying in 4th, 5th, 6th, 7th, 8th classes. In this study, 5E learning model is used in teaching a course in order to increase the participating students’ knowledge about ecological footprints and to calculate ecological footprints. Experimental method is used in this study. In data analysis, the paired samples t-test is used in for relevant samplings. The findings gathered indicate that ecological footprints of the participating students to the study decreased at the end of the study. It is determined that the mean of primary students’ ecological footprints differ from meaningfully according to level of the class and sex. Prospective solution offers are developed by handling the prospective effects of conclusions of the study on sustainable life and environmental education and conclusions’ importance in terms of learning and developing learning programmes with a critical point of view

  1. Let's Face(book) It: Analyzing Interactions in Social Network Groups for Chemistry Learning

    Science.gov (United States)

    Rap, Shelley; Blonder, Ron

    2016-01-01

    We examined how social network (SN) groups contribute to the learning of chemistry. The main goal was to determine whether chemistry learning could occur in the group discourse. The emphasis was on groups of students in the 11th and 12th grades who learn chemistry in preparation for their final external examination. A total of 1118 discourse…

  2. Report on the 19th SPACE Conference

    OpenAIRE

    Rune Gulev

    2008-01-01

    The 19th international space (European Network for Business Studies and Languages) conference that recently took place in Spain provided valuable insight into several areas of interest. Most notably, methods on how to successfully enhance the internationalization of higher learning institutions were shared through mobility and joint degrees programs. Furthermore, the conference provided an academic forum for a highly professional and earnest discourse on pertinent topics of relevance for high...

  3. Teachers’ Learning Design Practice for Students as Learning Designers

    DEFF Research Database (Denmark)

    Levinsen, Karin Tweddell; Sørensen, Birgitte Holm

    2018-01-01

    This paper contributes with elements of an emerging learning design methodology. The paper takes as its starting point the theory of Students as Learning Designers, which was developed by Sørensen and Levinsen and based on more than a decade of research-and-development projects in Danish primary...... schools (first to 10th grade). The research focussed on information and communication technology (ICT) within the Scandinavian tradition of Problem Oriented Project Pedagogy (POPP), Problem Based Learning (PBL) and students’ production. In recent years, the projects that provide the grounding...... for the theory have focussed specifically on learning designs that constitute students as learning designers of digital productions (both multimodal and coded productions). This includes learning designs that contribute to students’ empowerment, involvement and autonomy within the teacher-designed frameworks...

  4. The 13th Winter Conference on Medicinal and Bioorganic Chemistry.

    Science.gov (United States)

    Williams, Scott D

    2017-04-06

    The Medicinal and Bioorganic Chemistry Foundation (MBCF) hosted its 13 th biannual Winter Conference on Medicinal and Bioorganic Chemistry (WCMBC) this past January 22 nd -26 th in Steamboat Springs, Colorado (USA). The gathering this year kept true to the tradition of this conference series, with an impressive lineup of presenters from both academia and industry. With about 125 delegates, the conference took all the advantages of a mid-sized gathering: a sufficiently wide spectrum of scientists in attendance, yet an intimate atmosphere conducive to solid networking and frank, open discussions. This conference report summarizes the presentations that were given this year. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Toll-like receptor-2 agonist-allergen coupling efficiently redirects Th2 cell responses and inhibits allergic airway eosinophilia.

    Science.gov (United States)

    Krishnaswamy, Jayendra Kumar; Jirmo, Adan Chari; Baru, Abdul Mannan; Ebensen, Thomas; Guzmán, Carlos A; Sparwasser, Tim; Behrens, Georg M N

    2012-12-01

    Toll-like receptor (TLR) agonists beneficially modulate allergic airway inflammation. However, the efficiency of TLR agonists varies considerably, and their exact cellular mechanisms (especially of TLR 2/6 agonists) are incompletely understood. We investigated at a cellular level whether the administration of the pharmacologically improved TLR2/6 agonist S-[2,3-bispalmitoyiloxy-(2R)-propyl]-R-cysteinyl-amido-monomethoxy polyethylene glycol (BPP) conjugated to antigenic peptide (BPP-OVA) could divert an existing Th2 response and influence airway eosinophilia. The effects of BPP-OVA on airway inflammation were assessed in a classic murine sensitization/challenge model and an adoptive transfer model, which involved the adoptive transfer of in vitro differentiated ovalbumin (OVA)-specific Th2 cells. Functional T-cell stimulation by lung dendritic cells (DCs) was determined both in vitro and in vivo, combined with a cytokine secretion analysis. A single mucosal application of BPP-OVA efficiently delivered antigen, led to TLR2-mediated DC activation, and resulted in OVA-specific T-cell proliferation via lung DCs in vivo. In alternative models of allergic airway disease, a single administration of BPP-OVA before OVA challenge (but not BPP alone) significantly reduced airway eosinophilia, most likely through altered antigen-specific T-cell stimulation via DCs. Analyses of adoptively transferred Th2-biased cells after BPP-OVA administration in vivo suggested that BPP-OVA guides antigen-specific Th2 cells to produce significantly higher amounts of IFN-γ upon allergen challenge. In conclusion, our data show for the first time that a single mucosal administration of a TLR 2/6 agonist-allergen conjugate can provoke IFN-γ responses in Th2-biased cells and alleviate allergic airway inflammation.

  6. Peculiarities of Motor Abilities Development in 7th-8th-Graders

    Directory of Open Access Journals (Sweden)

    Ю. В. Мороз

    2015-09-01

    Full Text Available The pupose of the research is to define the peculiarities of motor abilities development in children of middle-school age. Research methods: theoretical analysis and collation of scientific and methodological literature; pedagogical testing; methods of mathematical statistics. To determine the effectiveness of realization of the developmental task of the physical education process at the beginning of the school year (in October 2014 and in March 2015, we tested the level of development of physical qualities in the 7th- and 8th-graders, 25 and 25 graders respectively, 13 of which in each class were boys and 12 — girls. Research results. The analysis of the materials shows that during the school year, the boys of the 7th grade showed reliably increased performance in standing long jumps (speed and strength qualities — 1.97%, raising the body from the lying position (strength — 26.46%, bent suspension (strength — 13.45%. The indicators have insignificantly (unreliably increased in the shuttle run 3×10 m (agility — 6.09%, and in body bending from the sitting position (flexibility — 6.25%. The girls showed reliably increased performance in the level of readiness: flexibility — 12%, strength — 12.09%, speed-strength qualities — 5.27%, agility — 7.77%. The analysis of the materials shows that during the school year the 8th-graders (boys reliably increased their physical readiness in speed-strength qualities — 0.8%, strength — 15.7%. The indicators of agility increased unreliably — 2.7%, as well as those of flexibility — 8%. The 8th‑graders (girls reliably improved their indicators in standing long jumps — 2.1%, in bent suspension — 18.8%, raising the body from the lying position in 30 seconds — 17.4%, body bending from the sitting position — 12 5%. The indicators agility improved unreliably — 3.4%. Conclusions. The data obtained are important in solving the pedagogical problems of schoolers’ physical education

  7. Decree-Law N0 678 of 26 November 1981 concerning the creation of local health centres

    International Nuclear Information System (INIS)

    1981-01-01

    This Decree-Law provides for direct employment of workers by the Regions in connection with the creation of adequate health centres and radioactive decontamination centres, following nuclear emergencies in areas where nuclear power plants are located. This Decree-Law was converted into Act N 0 12 of 26th January 1982 and published in the Official Gazette of 27th January 1982. (NEA) [fr

  8. Exchange of Th, U and Pu on macroporous ion exchange resins

    International Nuclear Information System (INIS)

    Nadkarni, M.N.; Mayankutty, P.C.; Pillai, N.S.; Shinde, S.S.

    1977-01-01

    Absorption of Th, U and Pu on macroporous ion exchangers, Amberlyst 15 (cationic) and Amberlyst A-26 (anionic) were studied in nitric acid solutions and the results were found comparable with those on their microreticular counter parts, Dowex 50x8 and Dowex IX4. With a view to evalute the efficiency of Amberlyst A-26 for the final purification of plutonium from the purex process stream, detailed studies conducted to determine the breakthrough capacity of Pu(IV) from 7.2 M nitric acid, elution by 0.5 M nitric acid and the decontamination factors for uranium and zirconium-95. Because of its faster kinetics, Amberlyst A-26 exhibited a much more efficient elution of Pu(IV) by 0.5 M nitric acid than Dowex IX4. (author)

  9. Teachers’ Learning Design Practice for Students as Learning Designers

    DEFF Research Database (Denmark)

    Levinsen, Karin Tweddell; Sørensen, Birgitte Holm

    2018-01-01

    schools (first to 10th grade). The research focussed on information and communication technology (ICT) within the Scandinavian tradition of Problem Oriented Project Pedagogy (POPP), Problem Based Learning (PBL) and students’ production. In recent years, the projects that provide the grounding...

  10. Concentration of thorium isotopes and the activity ratios of 230Th/232Th and 228Th/232Th in seawater in the Pacific Ocean

    International Nuclear Information System (INIS)

    Miyake, Yasuo; Sugimura, Yukio; Yasujima, Tadahide.

    1978-01-01

    The concentration of thorium isotopes and the activity ratios of 230 Th/ 232 Th and 228 Th/ 232 Th in 500 l sea water samples collected in the Pacific Ocean were determined. Thorium isotopes were analyzed by alpha-ray spectrometry after separating them from other elements with an anion exchange resin. The average content of thorium ( 232 Th) of 0.9 ng l -1 was obtained in the open Pacific water. The average contents of 230 Th and 228 Th were 2.1 x 10 -2 pgl -1 and 1.2 agl -1 respectively. It was found that the ratios of 230 Th/ 232 Th and 228 Th/ 232 Th ranged respectively from 1.0 to 29, and from 0.4 to as high as 128. (author)

  11. Th1/Th2 cytokine expression in diabetic retinopathy.

    Science.gov (United States)

    Cao, Y L; Zhang, F Q; Hao, F Q

    2016-07-15

    Diabetic retinopathy (DR), an important complication of diabetes mellitus (DM), is not well understood. T helper cell balance (Th1/Th2) is involved in various autoimmune diseases; however, its role in DR is not understood. This study explores changes in Th1 and Th2 cytokine expression during DR. Blood samples were collected from 25 healthy volunteers (normal control group), 35 patients with type 2 DM (T2DM group) without DR, and 30 cases of T2DM patients with DR (DR group). Real-time PCR was used to measure mRNA expression of IL-2 and TNF-α, secreted from Th1 cells, and of IL-4 and IL-10, secreted from Th2 cells. We used ELISA to detect cytokine expression in serum to analyze the correlation between Th1 and Th2 cytokines. IL-2 and TNF-αmRNA and protein expression levels in the T2DM and DR groups were significantly higher than in the normal control group (P 0.05). IL-2 and TNF-αwere negatively correlated with IL-4 and IL-10 in the DR group, respectively. We found that Th1 cytokine secretion was higher and Th2 cytokines secretion was lower during DR, leading to a Th1/ Th2 imbalance, suggesting that Th1/Th2 imbalance is a side effect for DR occurrence and development.

  12. Chairman of the DELL Board of Directors and Chief Executive Officer Michael S. Dell with CERN Director-General R. Heuer and in front of the ATLAS detector (centre) with ATLAS Deputy Spokesperson A. Lankford (left) and Information Technology Department Head F. Hemmer on 26th January 2010.

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    Chairman of the DELL Board of Directors and Chief Executive Officer Michael S. Dell with CERN Director-General R. Heuer and in front of the ATLAS detector (centre) with ATLAS Deputy Spokesperson A. Lankford (left) and Information Technology Department Head F. Hemmer on 26th January 2010.

  13. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in Digital Age (14th, Vilamoura, Algarve, Portugal, October 18-20, 2017)

    Science.gov (United States)

    Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaías, Pedro, Ed.

    2017-01-01

    These proceedings contain the papers of the 14th International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2017), 18-20 October 2017, which has been organized by the International Association for Development of the Information Society (IADIS) and endorsed by the Japanese Society for Information and Systems in…

  14. 11th International Conference on Computing and Information Technology

    CERN Document Server

    Meesad, Phayung; Boonkrong, Sirapat

    2015-01-01

    This book presents recent research work and results in the area of communication and information technologies. The book includes the main results of the 11th International Conference on Computing and Information Technology (IC2IT) held during July 2nd-3rd, 2015 in Bangkok, Thailand. The book is divided into the two main parts Data Mining and Machine Learning as well as Data Network and Communications. New algorithms and methods of data mining asr discussed as well as innovative applications and state-of-the-art technologies on data mining, machine learning and data networking.

  15. Implementation and Evaluation of Web-Based Learning Activities on Bonding and the Structure of Matter for 10-th Grade Chemistry

    Science.gov (United States)

    Frailich, Marcel

    This study deals with the development, implementation, and evaluation of web-based activities associated with the topic of chemical bonding , as taught in 10th grade chemistry. A website was developed entitled: "Chemistry and the Chemical Industry in the Service of Mankind", its URL is: http://stwww.weizmann.ac.il/g-chem/learnchem (Kesner, Frailich, & Hofstein, 2003). The main goal of this study was to assess the educational effectiveness of website activities dealing with the chemical bonding concept. These activities include visualization tools, as well as topics relevant to daily life and industrial applications. The study investigated the effectiveness of a web-based learning environment regarding the understanding of chemical bonding concepts, students' perceptions of the classroom learning environment, their attitudes regarding the relevance of learning chemistry to everyday life, and their interest in chemistry studies. As mentioned before, in the present study we focused on activities (from the website), all of which deal with chemical bonding concept. The following are the reasons for the decision to focus on this topic: (1) Chemical bonding is a key concept that is taught in 10th grade chemistry in high school. It provides the basis for many other chemistry topics that are taught later, and (2) Chemical bonding is a difficult for students using existing tools (e. g., static models in books, ball-and- stick models), which are insufficient to demonstrate the abstract nature phenomena associated with this topic. The four activities developed for this study are (1) models of the atomic structure, (2) metals -- structure and properties, (3) ionic substances in everyday life and in industry, and (4) molecular substances -- structure, properties, and uses. The study analyzed both quantitative and qualitative research. The quantitative tools of the study included: A Semantic Differential questionnaire and a Chemistry Classroom Web-Based Learning Environment

  16. OECD - HRP Summer School on Light Water Reactor Structural Materials. August 26th - 30th, 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    In cooperation with the OECD Nuclear Energy Agency (NEA), the Halden Reactor Project organised a Summer School on Light Water Reactor Structural Materials in the period August 26 - 30, 2002. The summer school was primarily intended for people who wanted to become acquainted with materials-related subjects and issues without being experts. It is especially hoped that the summer school served to transfer knowledge to the ''young generation'' in the field of nuclear. Experts from Halden Project member organisations were solicited for the following programme: (1) Overview of The Nuclear Community and Current Issues, (2) Regulatory Framework for Ensuring Structural Integrity, (3) Non-Destructive Testing for Detection of Cracks, (4) Part I - Basics of Radiation and Radiation Damage, (5) Part II - Radiation Effects on Reactor Internal Materials, (6) Water Chemistry and Radiolysis Effects in LWRs, (7) PWR and Fast Breeder Reactor Internals, (8) PWR and Fast Breeder Reactor Internals, (9) Secondary Side Corrosion Cracking of PWR Steam Generator Tubes, (10) BWR Materials and Their Interaction with the Environment, (11) Radiation Damage in Reactor Pressure Vessels.

  17. OECD - HRP Summer School on Light Water Reactor Structural Materials. August 26th - 30th, 2002

    International Nuclear Information System (INIS)

    2002-01-01

    In cooperation with the OECD Nuclear Energy Agency (NEA), the Halden Reactor Project organised a Summer School on Light Water Reactor Structural Materials in the period August 26 - 30, 2002. The summer school was primarily intended for people who wanted to become acquainted with materials-related subjects and issues without being experts. It is especially hoped that the summer school served to transfer knowledge to the ''young generation'' in the field of nuclear. Experts from Halden Project member organisations were solicited for the following programme: (1) Overview of The Nuclear Community and Current Issues, (2) Regulatory Framework for Ensuring Structural Integrity, (3) Non-Destructive Testing for Detection of Cracks, (4) Part I - Basics of Radiation and Radiation Damage, (5) Part II - Radiation Effects on Reactor Internal Materials, (6) Water Chemistry and Radiolysis Effects in LWRs, (7) PWR and Fast Breeder Reactor Internals, (8) PWR and Fast Breeder Reactor Internals, (9) Secondary Side Corrosion Cracking of PWR Steam Generator Tubes, (10) BWR Materials and Their Interaction with the Environment, (11) Radiation Damage in Reactor Pressure Vessels

  18. Work-Based Learning: Good News, Bad News and Hope. Research Brief.

    Science.gov (United States)

    Bottoms, Gene; Presson, Alice

    The effects of work-based learning on student achievement were examined by analyzing data from the 1996 High Schools That Work (HSTW) assessment. The comparison focused on the experiences of 12th-graders in structured work-based learning programs and 12th-graders with after-school jobs. A larger percentage of students earning school credit for…

  19. Neutronic simulation of a research reactor core of (232Th, 235U)O2 fuel using MCNPX2.6 code

    International Nuclear Information System (INIS)

    Feghhi, Seyed Amir Hossein; Rezazadeh, Marzieh; Kadi, Yacine; ); Tenreiro, Claudio; Aref, Morteza; Gholamzadeh, Zohreh

    2013-01-01

    The small reactor design for the remote and less developed areas of the user countries should have simple features in view of the lack of infra-structure and resources. Many researchers consider long core life with no on-site refuelling activity as a primary feature for the small reactor design. Long core life can be achieved by enhancing internal conversion rate of fertile to fissile materials. For that purpose, thorium cycle can he adopted because a high fissile production rate of 233 U converted from 232 Th can be expected in the thermal energy region. A simple nuclear reactor core arranged 19 assemblies in hexagonal structure, using thorium-based fuel and heavy water as coolant and moderator was simulated using MCNPX2.6 code, aiming an optimized critical assembly. Optimized reflector thickness and gap between assemblies were determined to achieve minimum neutron leakage and void reactivity. The result was a more compact core, where assemblies were designed having 19-fuel pins in 1.25 pitch-to-diameter ratio. Optimum reflector thickness of 15 cm resulted in minimal neutron leakage in view of economic limitations. A 0.5 cm gap between assembles achieved more safety and 2.2 % enrichment requirements. The present feasibility study suggests a thermal core of acceptable neutronic parameters to achieve a simple and safe core. (author)

  20. Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells.

    Science.gov (United States)

    Basdeo, Sharee A; Cluxton, Deborah; Sulaimani, Jamal; Moran, Barry; Canavan, Mary; Orr, Carl; Veale, Douglas J; Fearon, Ursula; Fletcher, Jean M

    2017-03-15

    Th17 cells are an important therapeutic target in autoimmunity. However, it is known that Th17 cells exhibit considerable plasticity, particularly at sites of autoimmune inflammation. Th17 cells can switch to become ex-Th17 cells that no longer produce IL-17 but produce IFN-γ. These ex-Th17 cells are also called nonclassical Th1 cells because of their ability to produce IFN-γ, similar to Th1 cells; however, it is unclear whether they resemble Th1 or Th17 cells in terms of their function and regulation, and whether they have a pathogenic role in autoimmunity. We compared the phenotypic and functional features of human Th17, Th1, and ex-Th17 cell populations. Our data showed that despite their loss of IL-17 expression, ex-Th17 cells were more polyfunctional in terms of cytokine production than either Th1 or bona fide Th17 cells, and produced increased amounts of proinflammatory cytokines. The proliferative brake on Th17 cells appeared to be lifted because ex-Th17 cells proliferated more than Th17 cells after stimulation. In contrast with Th1 and Th17 cells, ex-Th17 cells were highly resistant to suppression of proliferation and cytokines by regulatory T cells. Finally, we showed that ex-Th17 cells accumulated in the joints of rheumatoid arthritis patients. Taken together, these data indicate that human ex-Th17 cells are functionally distinct from Th1 and Th17 cells, and suggest that they may play a pathogenic role at sites of autoimmunity, such as the rheumatoid arthritis joint where they accumulate. These findings have implications for therapeutic strategies that target IL-17, because these may not inhibit pathogenic ex-Th17 cells. Copyright © 2017 by The American Association of Immunologists, Inc.

  1. Suicidal ideation among students of the 7th, 8th, and 9th grades in the State of Lara, Venezuela: the Global School Health Survey.

    Science.gov (United States)

    Granero, Ricardo; Poni, Esteban; Poni, Carolin

    2008-12-01

    Suicidal behavior among adolescents is not a well-explored public health problem. Health policy decision-making on suicidal behavior needs reliable information on the prevalence of suicidal ideation (SI) and its associated risk factors to produce health promotion and prevention programs. The Global School Health Survey is a self-administered survey done on a random probabilistic sample among students of the 7th, 8th, and 9th grades in the Lara State, Venezuela, school period 2003 to 2004. Point prevalence of SI and associated factors were included and the odds (OR) of having SI was calculated given selected factors. Two-thousand seventy (2070) respondents, of which 13.5 % reported having SI in the last 12 months, and in females more than males (14.6% vs. 11.7%). The OR for SI, according to an associated risk factor, were among (a) females: age > or = 14 years (2.2), worries (3.42), loneliness (8.8), ever had sexual intercourse (5.58), alcohol (8.43) and (b) males: having only one or non close friends (3.69), alcohol (12.36), ever had sexual intercourse (2.73). Behavioral risk factors are relatively new in the field of surveillance systems; therefore, results on SI should be cautiously taken into consideration and a wide discussion should be encouraged as we learn how to best use the results for health promotion and disease prevention.

  2. Teachers’ Learning Design Practice for Students as Learning Designers

    DEFF Research Database (Denmark)

    Levinsen, Karin Tweddell; Sørensen, Birgitte Holm

    2018-01-01

    that simultaneously scaffold students’ subject-related inquiry, agency, reflection and learning. Research studies have documented that this approach constitutes arenas that support students’ deep learning and mastery of both transdisciplinary and subject matter, along with their acquisition of digital literacy and 21......This paper contributes with elements of an emerging learning design methodology. The paper takes as its starting point the theory of Students as Learning Designers, which was developed by Sørensen and Levinsen and based on more than a decade of research-and-development projects in Danish primary...... schools (first to 10th grade). The research focussed on information and communication technology (ICT) within the Scandinavian tradition of Problem Oriented Project Pedagogy (POPP), Problem Based Learning (PBL) and students’ production. In recent years, the projects that provide the grounding...

  3. Contextual Approach with Guided Discovery Learning and Brain Based Learning in Geometry Learning

    Science.gov (United States)

    Kartikaningtyas, V.; Kusmayadi, T. A.; Riyadi

    2017-09-01

    The aim of this study was to combine the contextual approach with Guided Discovery Learning (GDL) and Brain Based Learning (BBL) in geometry learning of junior high school. Furthermore, this study analysed the effect of contextual approach with GDL and BBL in geometry learning. GDL-contextual and BBL-contextual was built from the steps of GDL and BBL that combined with the principles of contextual approach. To validate the models, it uses quasi experiment which used two experiment groups. The sample had been chosen by stratified cluster random sampling. The sample was 150 students of grade 8th in junior high school. The data were collected through the student’s mathematics achievement test that given after the treatment of each group. The data analysed by using one way ANOVA with different cell. The result shows that GDL-contextual has not different effect than BBL-contextual on mathematics achievement in geometry learning. It means both the two models could be used in mathematics learning as the innovative way in geometry learning.

  4. From Cloister to Commons: Concepts and Models for Service-Learning in Religious Studies. AAHE's Series on Service-Learning in the Disciplines.

    Science.gov (United States)

    Devine, Richard, Ed.; Favazza, Joseph A., Ed.; McLain, F. Michael, Ed.

    This essays in this volume, 19th in a series, discuss why and how service-learning can be implemented in Religious Studies and what that discipline contributes to the pedagogy of service-learning. Part 1, "Service-Learning and the Dilemma of Religious Studies," contains: (1) "Service-Learning and the Dilemma of Religious Studies: Descriptive or…

  5. 8th International Conference KES-AMSTA

    CERN Document Server

    Kusek, Mario; Lovrek, Ignac; Howlett, Robert; Jain, Lakhmi

    2014-01-01

    Agents and multi-agent systems are related to a modern software paradigm which has long been recognized as a promising technology for constructing autonomous, complex and intelligent systems. The topics covered in this volume include agent-oriented software engineering, agent co-operation, co-ordination, negotiation, organization and communication, distributed problem solving, multi-agent communities, rational and clustering agents, learning paradigms, agent cognitive models, and heterogenous multi-agent environments.   The volume highlights new trends and challenges in agent and multi-agent research and includes 30 papers classified in five specific topics: Modeling and logic agents, Knowledge based agent systems, Cognitive and cooperative multi-agent systems, Agent-based Modeling and Simulation, and Learning Paradigms and Applications: Agent-based Approach. The published papers have been presented at the 8th KES Conference on Agent and Multi-Agent Systems – Technologies and Applications (KES-AMSTA 2014) ...

  6. Open Learning for Smart Education: Open educational policies, strategies & access for all

    NARCIS (Netherlands)

    Stracke, Christian M.

    2016-01-01

    keynote on Open Learning at the International IEEE EDUCON Conference 2016: I will speak about “Open Learning for Smart Education: Open educational policies, strategies and access for all”. This year EDUCON is taking place from 10th to 13th of April 2016 in Abu Dhabi. My questions of the keynote

  7. Promoting Cooperative Learning in the Classroom: Comparing Explicit and Implicit Training Techniques

    Directory of Open Access Journals (Sweden)

    Anne Elliott

    2003-07-01

    Full Text Available In this study, we investigated whether providing 4th and 5th-grade students with explicit instruction in prerequisite cooperative-learning skills and techniques would enhance their academic performance and promote in them positive attitudes towards cooperative learning. Overall, students who received explicit training outperformed their peers on both the unit project and test and presented more favourable attitudes towards cooperative learning. The findings of this study support the use of explicitly instructing students about the components of cooperative learning prior to engaging in collaborative activities. Implications for teacher-education are discussed.

  8. Concentration of 232Th, 230Th and 228Th in various tissues of Japanese subjects

    International Nuclear Information System (INIS)

    Takizawa, Y.; Qingmei, H.; Hisamatsu, S.; Abe, T.

    1997-01-01

    The concentration of 232 Th, 230 Th and 228 Th in various human tissues of Japanese subjects obtained at autopsies are reported. The tissue samples were weighed, spiked with 234 Th tracer and ashed by acid. The solution was dried on a hot-plate. Separation of thorium radionuclides was accomplished through cation-exchange resin chromatography and electrodeposition. The concentrations of thorium isotopes were measured by α-spectrometry. Thorium-232 and 230 Th concentrations were found to be highest in lung, followed by bone. The maximum concentration of 228 Th was in bone. The lowest concentrations of thorium isotopes were in muscle. (author)

  9. Proceedings of the 20th International Meshing Roundtable

    CERN Document Server

    2012-01-01

    This volume contains the articles presented at the 20th International Meshing Roundtable (IMR) organized, in part, by Sandia National Laboratories and was held in Paris, France on Oct 23-26, 2011. This is the first year the IMR was held outside the United States territory. Other sponsors of the 20th IMR are Systematic Paris Region Systems & ICT Cluster, AIAA, NAFEMS, CEA, and NSF. The Sandia National Laboratories started the first IMR in 1992, and the conference has been held annually since. Each year the IMR brings together researchers, developers, and application experts, from a variety of disciplines, to present and discuss ideas on mesh generation and related topics. The topics covered by the IMR have applications in numerical analysis, computational geometry, computer graphics, as well as other areas, and the presentations describe novel work ranging from theory to application.     .

  10. Teaching systems thinking to 4th and 5th graders using Environmental Dashboard display technology.

    Science.gov (United States)

    Clark, Shane; Petersen, John E; Frantz, Cindy M; Roose, Deborah; Ginn, Joel; Rosenberg Daneri, Daniel

    2017-01-01

    Tackling complex environmental challenges requires the capacity to understand how relationships and interactions between parts result in dynamic behavior of whole systems. There has been convincing research that these "systems thinking" skills can be learned. However, there is little research on methods for teaching these skills to children or assessing their impact. The Environmental Dashboard is a technology that uses "sociotechnical" feedback-information feedback designed to affect thought and behavior. Environmental Dashboard (ED) combines real-time information on community resource use with images and words that reflect pro-environmental actions of community members. Prior research indicates that ED supports the development of systems thinking in adults. To assess its impact on children, the technology was installed in a primary school and children were passively exposed to ED displays. This resulted in no measurable impact on systems thinking skills. The next stage of this research examined the impact of actively integrating ED into lessons on electricity in 4th and 5th grade. This active integration enhanced both content-related systems thinking skills and content retention.

  11. The mobility of U and Th in subduction zone fluids: an indicator of oxygen fugacity and fluid salinity

    Science.gov (United States)

    Bali, Enikő; Audétat, Andreas; Keppler, Hans

    2011-04-01

    The solubility of U and Th in aqueous solutions at P-T-conditions relevant for subduction zones was studied by trapping uraninite or thorite saturated fluids as synthetic fluid inclusions in quartz and analyzing their composition by Laser Ablation-ICPMS. Uranium is virtually insoluble in aqueous fluids at Fe-FeO buffer conditions, whereas its solubility increases both with oxygen fugacity and with salinity to 960 ppm at 26.1 kbar, Re-ReO2 buffer conditions and 14.1 wt% NaCl in the fluid. At 26.1 kbar and 800°C, uranium solubility can be reproduced by the equation: log {{U}} = 2.681 + 0.1433log f{{O}}2 + 0.594{{Cl,}} where fO2 is the oxygen fugacity, and Cl is the chlorine content of the fluid in molality. In contrast, Th solubility is generally low (uranium increases strongly both with oxygen fugacity and with salinity. We show that reducing or NaCl-free fluids cannot produce primitive arc magmas with U/Th ratio higher than MORB. However, the dissolution of several wt% of oxidized, saline fluids in arc melts can produce U/Th ratios several times higher than in MORB. We suggest that observed U/Th ratios in arc magmas provide tight constraints on both the salinity and the oxidation state of subduction zone fluids.

  12. The development of learning material using learning cycle 5E model based stem to improve students’ learning outcomes in Thermochemistry

    Science.gov (United States)

    sugiarti, A. C.; suyatno, S.; Sanjaya, I. G. M.

    2018-04-01

    The objective of this study is describing the feasibility of Learning Cycle 5E STEM (Science, Technology, Engineering, and Mathematics) based learning material which is appropriate to improve students’ learning achievement in Thermochemistry. The study design used 4-D models and one group pretest-posttest design to obtain the information about the improvement of sudents’ learning outcomes. The subject was learning cycle 5E based STEM learning materials which the data were collected from 30 students of Science class at 11th Grade. The techniques used in this study were validation, observation, test, and questionnaire. Some result attain: (1) all the learning materials contents were valid, (2) the practicality and the effectiveness of all the learning materials contents were classified as good. The conclution of this study based on those three condition, the Learnig Cycle 5E based STEM learning materials is appropriate to improve students’ learning outcomes in studying Thermochemistry.

  13. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA) (13th, Mannheim, Germany, October 28-30, 2016)

    Science.gov (United States)

    Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaias, Pedro, Ed.

    2016-01-01

    These proceedings contain the papers of the 13th International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2016), October 28-30, 2016, which has been organized by the International Association for Development of the Information Society (IADIS), co-organized by the University of Mannheim, Germany, and endorsed by the…

  14. Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA) (11th, Porto, Portugal, October 25-27, 2014)

    Science.gov (United States)

    Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaias, Pedro, Ed.

    2014-01-01

    These proceedings contain the papers of the 11th International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2014), October 25-27, 2014, which has been organized by the International Association for Development of the Information Society (IADIS) and endorsed by the Japanese Society for Information and Systems in…

  15. LearnSafe. Learning organisations for nuclear safety

    International Nuclear Information System (INIS)

    Wahlstroem, B.; Kettunen, J.; Reiman, T.

    2005-03-01

    The nuclear power industry is currently undergoing a period of major change, which has brought with it a number of challenges. These changes have forced the nuclear power plants to initiate their own processes of change in order to adapt to the new situation. This adaptation must not compromise safety at any time, but during a rapid process of change there is a danger that minor problems may trigger a chain of events leading to a degraded safety. Organisational learning has been identified as an important component in ensuring the continued safety and efficiency of nuclear organisations. In response to these challenges a project LearnSafe 'Learning organisations for nuclear safety' was set up and funded by the European Community under the 5th Euratom Framework Programme. The present report gives an account of the LearnSafe project and its major results. (orig.)

  16. Proceedings of the Seventh International Conference on Educational Data Mining (EDM) (7th, London, United Kingdom, July 4-7, 2014)

    Science.gov (United States)

    Stamper, John, Ed.; Pardos, Zachary, Ed.; Mavrikis, Manolis, Ed.; McLaren, Bruce M., Ed.

    2014-01-01

    The 7th International Conference on Education Data Mining held on July 4th-7th, 2014, at the Institute of Education, London, UK is the leading international forum for high-quality research that mines large data sets in order to answer educational research questions that shed light on the learning process. These data sets may come from the traces…

  17. The 13th international workshop on targetry and target chemistry proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Haroun, S. (SFU, TRIUMF (Canada)); Givskov, A.; Jensen, Mikael (Technical Univ. of Denmark. Risoe National Laboratory for Sustainable Energy, Radiation Research Division, Roskilde (Denmark))

    2011-06-15

    This report contains the complete proceedings of the 13th International Workshop on Targetry and Target Chemistry. The Workshop was held at Risoe National Laboratory for Sustainable Energy on July 26-28 2010. The workshop deals with the development of methods and systems for efficient production of radioactive isotopes with accelerators. The WTTC series of workshops was initiated for the purpose of exchanging information about the problems and solutions associated with the production of radioisotopes for biomedical research and their applications to the diagnosis and treatment of disease. The goal of the WTTC is to advance the science associated with radioisotope production targetry. The Workshops are designed to bring experienced targetry scientists together with newcomers to the field, both from industry and academia, to discuss issues of targetry and target chemistry and approaches to exploring in situ target chemistry and the engineering required to optimize production yields. In the workshop, experience, ideas and information are freely and openly shared; learning and collaborations are fostered, with active participation by all attendees. This participation includes both formal and informal sessions. The present proceedings captures both submitted abstracts and the actual presentations showed during the very successful workshop meeting number 13 in the row, the WTTC13. (Author)

  18. The 13th international workshop on targetry and target chemistry proceedings

    International Nuclear Information System (INIS)

    Haroun, S.; Givskov, A.; Jensen, Mikael

    2011-06-01

    This report contains the complete proceedings of the 13th International Workshop on Targetry and Target Chemistry. The Workshop was held at Risoe National Laboratory for Sustainable Energy on July 26-28 2010. The workshop deals with the development of methods and systems for efficient production of radioactive isotopes with accelerators. The WTTC series of workshops was initiated for the purpose of exchanging information about the problems and solutions associated with the production of radioisotopes for biomedical research and their applications to the diagnosis and treatment of disease. The goal of the WTTC is to advance the science associated with radioisotope production targetry. The Workshops are designed to bring experienced targetry scientists together with newcomers to the field, both from industry and academia, to discuss issues of targetry and target chemistry and approaches to exploring in situ target chemistry and the engineering required to optimize production yields. In the workshop, experience, ideas and information are freely and openly shared; learning and collaborations are fostered, with active participation by all attendees. This participation includes both formal and informal sessions. The present proceedings captures both submitted abstracts and the actual presentations showed during the very successful workshop meeting number 13 in the row, the WTTC13. (Author)

  19. EVALUATION OF THE LEARNING SYSTEM BASED ON RESEARCH (SABI IN THE CICS UMA IPN BIOCHEMISTRY UNIT

    Directory of Open Access Journals (Sweden)

    Blanca Elisa Pérez-Magaña

    2014-07-01

    Full Text Available Learning is a steward, permanent, and participatory process where: the apprentice, teacher, classmates, institution and other social factors where the student performs. As detonator of learning is research, which is made from real events that are addressed on the basis of the scientific development of the State of the art. One of the key elements in the professional training of students is the method that is used. Research-based learning system is an educational innovation (SABI, which was used in the learning of basic sciences of the Cardiovascular apparatus in generations unit 33rd, 34th, 35th, 36th and 37th generations in the years of 2008 to 2012's career in medicine and as a result was a decrease in the number of students reproachedimproving achievement. This method is an excellent alternative in the teaching-learning process and can be used both in groups with a variable number of students.

  20. Proceedings of the 2nd Workshop on Awareness and Reflection in Technology-Enhanced Learning

    NARCIS (Netherlands)

    Moore, Adam; Pammer, Viktoria; Pannese, Lucia; Prilla, Michael; Rajagopal, Kamakshi; Reinhardt, Wolfgang; Ullman, Thomas; Voigt, Christian

    2013-01-01

    Moore, A., Pammer, V., Pannese, L., Prilla, M., Rajagopal, K., Reinhardt, W., Ullman, Th. D., & Voigt, Ch. (Eds.) (2012). Proceedings of the 2nd Workshop on Awareness and Reflection in Technology Enhanced Learning. In conjunction with the 7th European Conference on Technology Enhanced Learning: 21st

  1. Lifelong learning in aviation and medicine; Comments and suggestions

    NARCIS (Netherlands)

    Boshuizen, Els

    2011-01-01

    Boshuizen, H. P. A. (2010, 25-27 August). Lifelong learning in aviation and medicine; Comments and suggestions. Discussion at the 5th EARLI-SIG14 Learning and Professional Development, Munich, Germany.

  2. The Effectiveness of Cooperative Learning Methods on 7th Level “The Structure of Matter and Properties” Unit

    Directory of Open Access Journals (Sweden)

    Yasemin KOÇ

    2016-04-01

    Full Text Available The aim of this research are to determine the effectiveness of Student Teams-Achievement Division (STAD and Reading-Writing-Application (RWA methods of cooperative learning model on academic achievement at the unit of 7th Level “The Structure of Matter and Properties” and students’ views related to methods. The sample of this research are 102 students from two different secondary school in Ağrı. As data collecting tools, Pre-Knowledge Test (PKT, Academic Achievement Test (AAT and Scale Methods Views (SMV is used. For the analysis of the obtained data, one-way variance analysis (ANOVA was used for pre- test and analysis covariance (ANCOVA for academic achievement test because of significant differences in the groups’ pre- test. Descriptive statistics for students’ views about methods are used. It was found that RWA and STAD have similar effects on students’ academic achievement and students instructed with these techniques are more successful than students instructed with teacher centered instruction.

  3. Creating by Reusing Learning Design Solutions

    NARCIS (Netherlands)

    Hernández-Leo, Davinia; Harrer, Andreas; Dodero, Juan Manuel; Asensio-Pérez, Juan; Burgos, Daniel

    2006-01-01

    Hernández-Leo, D., Harrer, A., Dodero, J. M., Asension-Pérez, J. I., & Burgos, D. (2006). Creating by reusing Learning Design solutions. Proceedings of 8th Simposo Internacional de Informática Educativa, León, Spain: IEEE Technical Committee on Learning Technology. Retrieved October 3rd, 2006, from

  4. Knowledge Sharing Practice in a Play-Like Learning Environment

    DEFF Research Database (Denmark)

    Benjaminsen, Nana

    2007-01-01

    The topic of this paper is play-like learning as it occurs when technology based learning environments is invited into the classroom. Observations of 5th grade classes playing with Lego Robolab, is used to illustrate that different ways of learning becomes visible when digital technology...

  5. Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gamma as an intrinsic negative regulator of viral replication

    Science.gov (United States)

    2013-01-01

    Background We previously demonstrated that primary Th1Th17 cells are highly permissive to HIV-1, whereas Th1 cells are relatively resistant. Molecular mechanisms underlying these differences remain unknown. Results Exposure to replication competent and single-round VSV-G pseudotyped HIV strains provide evidence that superior HIV replication in Th1Th17 vs. Th1 cells was regulated by mechanisms located at entry and post-entry levels. Genome-wide transcriptional profiling identified transcripts upregulated (n = 264) and downregulated (n = 235) in Th1Th17 vs. Th1 cells (p-value Th17 (nuclear receptors, trafficking, p38/MAPK, NF-κB, p53/Ras, IL-23) vs. Th1 cells (proteasome, interferon α/β). Differentially expressed genes were classified into biological categories using Gene Ontology. Th1Th17 cells expressed typical Th17 markers (IL-17A/F, IL-22, CCL20, RORC, IL-26, IL-23R, CCR6) and transcripts functionally linked to regulating cell trafficking (CEACAM1, MCAM), activation (CD28, CD40LG, TNFSF13B, TNFSF25, PTPN13, MAP3K4, LTB, CTSH), transcription (PPARγ, RUNX1, ATF5, ARNTL), apoptosis (FASLG), and HIV infection (CXCR6, FURIN). Differential expression of CXCR6, PPARγ, ARNTL, PTPN13, MAP3K4, CTSH, SERPINB6, PTK2, and ISG20 was validated by RT-PCR, flow cytometry and/or confocal microscopy. The nuclear receptor PPARγ was preferentially expressed by Th1Th17 cells. PPARγ RNA interference significantly increased HIV replication at levels post-entry and prior HIV-DNA integration. Finally, the activation of PPARγ pathway via the agonist Rosiglitazone induced the nuclear translocation of PPARγ and a robust inhibition of viral replication. Conclusions Thus, transcriptional profiling in Th1Th17 vs. Th1 cells demonstrated that HIV permissiveness is associated with a superior state of cellular activation and limited antiviral properties and identified PPARγ as an intrinsic negative regulator of viral replication. Therefore, triggering PPARγ pathway via non

  6. 25th Annual International Laser Physics Workshop (LPHYS’16)

    International Nuclear Information System (INIS)

    2017-01-01

    EDITORIALDear Readers,The 25th annual International Laser Physics Workshop, LPHYS’16, took place in the city of Yerevan, Republic of Armenia. 319 participants from 32 countries attended the conference. It was hosted by the Yerevan Physics Institute, A Alikhanyan National Laboratory. This year the conference has been endorsed by the Optical Society (OSA), the year the society celebrates its 100th anniversary.The LPHYS’16 Steering Committee and the Advisory and Program Committee would like to extend their sincere gratitude to Dr. Koryun B Oganesyan (Chair of the Local Organizing Committee) and to his team for the outstanding job performed on organizing, arranging, managing and putting in order the conference. Their combined effort lead to a successful result.In this volume of the IOP Journal of Physics: Conference Series you will find selected proceedings of the Workshop in Yerevan.Please make a note that the 26th annual International Laser Physics Workshop (LPHYS’17) will take place from July 17 to July 21, 2017 in the city of Kazan, Russia hosted by the Kazan E K Zavoisky Physical-Technical Institute (KPhTI).With kind regards,Steering and Advisory and Program committeesLPHYS’16 (paper)

  7. Assessing Creative Thinking in Design-Based Learning

    Science.gov (United States)

    Doppelt, Yaron

    2009-01-01

    Infusing creative thinking competence through the design process of authentic projects requires not only changing the teaching methods and learning environment, but also adopting new assessment methods, such as portfolio assessment. The participants in this study were 128 high school pupils who have studied MECHATRONICS from 10th to 12th grades…

  8. La conception des environnements d’apprentissage : de la théorie à la pratique / de la pratique à la théorie La conception des environnements d’apprentissage : de la théorie à la pratique / de la pratique à la théorie

    Directory of Open Access Journals (Sweden)

    Jean-Jacques Quintin

    2000-06-01

    Full Text Available Cet article présente une approche en matière de conception d’environnements d’apprentissage multimédia qualifiée d’incrémentielle et d’itérative en ce sens qu’elle repose sur un affinage progressif du produit dans le cadre d’un partenariat étroit entre concepteur et client. L’approche proposée implique notamment la mise au point de prototypes qui feront l’objet de validations systématiques afin d’assurer l’adéquation avec les exigences et les contraintes du milieu d’accueil. S’appuyant sur une double posture de chercheur et de concepteur, l’approche se nourrit de la théorie en s’appuyant sur des modèles mais elle nourrit également la théorie à travers l’effort de modélisation qui l’accompagne.This paper describes a method of developing multimedia learning environments based on a close collaboration between the client and the team of developers. This approach uses different tools ans techniques (prototype, storyboard, concept maps... to progressively elaborate a product adequate to the client requirements and to ensure sufficient quality. Taking advantage of our specific situation of researchers and designers, the method is based on a coming and going between the pedagogical model and the development of a practical learning environment.

  9. 10th FSR (Field and Service Robotics)

    CERN Document Server

    Barfoot, Timothy

    2016-01-01

    This book contains the proceedings of the 10th FSR, (Field and Service Robotics) which is the leading single-track conference on applications of robotics in challenging environments. The 10th FSR was held in Toronto, Canada from 23-26 June 2015. The book contains 42 full-length, peer-reviewed papers organized into a variety of topics: Aquatic, Vision, Planetary, Aerial, Underground, and Systems. The goal of the book and the conference is to report and encourage the development and experimental evaluation of field and service robots, and to generate a vibrant exchange and discussion in the community. Field robots are non-factory robots, typically mobile, that operate in complex and dynamic environments: on the ground (Earth or other planets), under the ground, underwater, in the air or in space. Service robots are those that work closely with humans to help them with their lives. The first FSR was held in Canberra, Australia, in 1997. Since that first meeting, FSR has been held roughly every two years, cycling...

  10. IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation.

    Science.gov (United States)

    Mitchell, Ruth E; Hassan, Masriana; Burton, Bronwen R; Britton, Graham; Hill, Elaine V; Verhagen, Johan; Wraith, David C

    2017-09-12

    IL-10 is an immunomodulatory cytokine with a critical role in limiting inflammation in immune-mediated pathologies. The mechanisms leading to IL-10 expression by CD4 + T cells are being elucidated, with several cytokines implicated. We explored the effect of IL-4 on the natural phenomenon of IL-10 production by a chronically stimulated antigen-specific population of differentiated Th1 cells. In vitro, IL-4 blockade inhibited while addition of exogenous IL-4 to Th1 cultures enhanced IL-10 production. In the in vivo setting of peptide immunotherapy leading to a chronically stimulated Th1 phenotype, lack of IL-4Rα inhibited the induction of IL-10. Exploring the interplay of Th1 and Th2 cells through co-culture, Th2-derived IL-4 promoted IL-10 expression by Th1 cultures, reducing their pathogenicity in vivo. Co-culture led to upregulated c-Maf expression with no decrease in the proportion of T-bet + cells in these cultures. Addition of IL-4 also reduced the encephalitogenic capacity of Th1 cultures. These data demonstrate that IL-4 contributes to IL-10 production and that Th2 cells modulate Th1 cultures towards a self-regulatory phenotype, contributing to the cross-regulation of Th1 and Th2 cells. These findings are important in the context of Th1 driven diseases since they reveal how the Th1 phenotype and function can be modulated by IL-4.

  11. Determination of 232Th, 230Th and 228Th in liquid effluents from uranium mining

    International Nuclear Information System (INIS)

    Godoy, Jose Marcus de Oliveira

    1979-10-01

    A liquid scintillator αlpha spectrometer was built for the determination of Th- 228 , Th- 230 and Th- 232 in liquid effluents from Uranium mines and mills. The resolution of the αlpha spectrometer was found to be 200-300 KeV, when the scintillator was 8% T0P0, 0,77% scintimix-4 (91% PP0 and 9% Dimetil-P0P0P) and 10% of naphthalene in toluene. Aliquat-336 in xylene (30% v/v) was used to separate the thorium isotopes from other interfering radionuclides (U- 238 , U- 234 , Ra- 226 , Po- 210 ). Under the extraction experimental conditions, the detection limits were 1,2 pCi/1 for Th- 232 , 1,2 pCi/1 for Th- 230 and 0,9 pCi/1 for Th- 228 , for 1000 minutes of counting time. (author)

  12. Comparison of Values in 5th, 6th, 7th and 8th Grade Primary Education Music Class Students'? Workbooks According to Rokeach?s and Akbas's Value Classifications

    Science.gov (United States)

    Çakirer, H. Serdar

    2014-01-01

    The aim of the present study is to compare the values in the songs of 5th, 6th, 7th and 8th grade primary education music classes students? workbooks according to the value categorizations proposed by Rockeach and Akbas and which values among the categories mentioned are taught to the students in the 5th, 6th, 7th and 8th grade primary education…

  13. Cyberl@b: a platform for learning english in Costa Rican public high schools

    OpenAIRE

    Allen Quesada Pacheco

    2006-01-01

    Abstract: This paper covers the design and development of a noncommercial software for learning and practicing English called CyberL@b. It was developed at the School of Modern Languages at the University of Costa Rica. Its target population focuses on 7th, 8th and 9th graders at six public high schools in diverse urban and rural settings in Costa Rica.CyberL@b uses interactive media resources designed to engage student in learning English within authentic contexts.Cyberlab was designed to cr...

  14. Dissolution behaviour of 238U, 234U and 230Th deposited on filters from personal dosemeters

    International Nuclear Information System (INIS)

    Beckova, V.; Malatova, I.

    2008-01-01

    Kinetics of dissolution of 238 U, 234 U and 230 Th dust deposited on filters from personal alpha dosemeters was studied by means of a 26-d in vitro dissolution test with a serum ultra-filtrate simulant. Dosemeters had been used by miners at the uranium mine 'Dolni Rozinka' at Rozna, Czech Republic. The sampling flow-rate as declared by the producer is 4 l h -1 and the sampling period is typically 1 month. Studied filters contained 125 ± 6 mBq 238 U in equilibrium with 234 U and 230 Th; no 232 Th series nuclides were found. Half-time of rapid dissolution of 1.4 d for 238 U and 234 U and slow dissolution half-times of 173 and 116 d were found for 238 U and 234 U, respectively. No detectable dissolution of 230 Th was found. (authors)

  15. The Trajectory of Scholarship about Self-Regulated Learning

    Science.gov (United States)

    Winne, Philip H.

    2017-01-01

    The trajectory of scholarship about self-regulated learning (SRL) originates in mid-19th-century writings about learners' sense of responsibility in self education. Although Descartes's 17th-century writings implied mental activities consistent with metacognition, a central feature of SRL, these were inarticulate until Flavell and colleagues'…

  16. Determination of the activity concentration of {sup 230}Th in phosphoric acids produced in Brazil; Determinação da concentração de atividade de {sup 230}Th em ácidos fosfóricos produzidos no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Taddei, M.H.T.; Ferreira, M.T.; Fukuma, H.T.; Xavier, T.T.; Sousa, F.V.T.S., E-mail: tatianattx@gmail.com [Comissao Nacional de Energia Nuclear (LAPOC/CNEN), Pocos de Caldas, MG (Brazil). Laboratorio de Pocos de Caldas. Radioquimica

    2017-07-01

    The high uranium phosphate rock from Itataia, Brazil, was processed using the wet route in the dihydrate system to manufacture phosphoric acid. The uranium contained in phosphoric acid was recovered by the solvent extraction technique. The distribution of the long half-life radionuclides from the decay series of {sup 238}U and {sup 232}Th were evaluated in these processes. The {sup 26}Ra, {sup 228}Ra and {sup 210}Pb radionuclides were found predominantly in phosphogypsum, while the isotopes of {sup 228}Th, {sup 230}Th and {sup 232}Th predominated in phosphoric acid after extracting uranium. The main concern in the commercialization of phosphoric acid that will be produced in the Itataia plant is in relation to the content of {sup 230}Th. This work determined the content of these radionuclides in phosphoric acid from different locations in the country in order to compare.

  17. Down-regulation of the Th1, Th17, and Th22 pathways due to anti-TNF-α treatment in psoriasis.

    Science.gov (United States)

    Luan, Li; Han, Shixin; Wang, Hua; Liu, Xiaoming

    2015-12-01

    Psoriasis is a T-cell-mediated chronic inflammatory dermatosis. Th1, Th17 and Th22 cells are suggested to contribute to the pathogenesis of psoriasis. To determine whether treatment with the anti-tumor-necrosis-factor antagonist, adalimumab, induces significant modulation of the Th1, Th17 and Th22 pathways, and correlates cellular activity with clinical response. This study included 21 patients with moderate-to-severe psoriasis who were treated with adalimumab, and 10 healthy control subjects. Blood samples were collected at baseline and at week 12. Flow cytometry was used to analyze the frequency of circulating Th1, Th17 and Th22 cells. Real-time polymerase chain reaction was used to analyze the expression of T-bet (Th1-related), retinoid-acid receptor-related orphan receptor gamma t (RORγt, Th17-related) and aryl hydrocarbon receptor (AHR, Th22-related). An enzyme-linked immunosorbent assay was used to analyze the serum levels of IFN-γ, IL-17, IL-22, IL-6 and tumor necrosis factor-α (TNF-α). At baseline, the frequencies of Th1, Th17 and Th22 cells were higher in psoriasis patients compared to the healthy controls. The expression of transcription factors T-bet, RORγt and AHR, and the serum levels of IFN-γ, IL-17, IL-22, IL-6 and TNF-α were higher in psoriasis patients compared to the healthy controls. After adalimumab therapy, there was a significant decline in the frequencies of Th1, Th17 and Th22 cells, and a concomitant decrease in the levels of their associated transcription factors and cytokines. The results suggest that the anti-tumor-necrosis-factor antagonist, adalimumab, disrupts the Th1, Th17 and Th22 pathways, resulting in clinical improvement of psoriasis. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Relevance of Videogames in the Learning and Development of Young Children

    Science.gov (United States)

    Zhao, Zhuxuan; Linaza-Iglesias, José L.

    2015-01-01

    Introduction: The study was carried out with children of 2nd, 4th and 6th grades of elementary school in order to explore what and how will children learn from a completely new videogame. Method: We organized children from 2nd, 4th and 6th grades of elemental school, giving them chance to play a freshly released videogame by that time. We formed…

  19. Learning Physics through Project-Based Learning Game Techniques

    Science.gov (United States)

    Baran, Medine; Maskan, Abdulkadir; Yasar, Seyma

    2018-01-01

    The aim of the present study, in which Project and game techniques are used together, is to examine the impact of project-based learning games on students' physics achievement. Participants of the study consist of 34 9th grade students (N = 34). The data were collected using achievement tests and a questionnaire. Throughout the applications, the…

  20. Thorium Th

    International Nuclear Information System (INIS)

    Busev, A.I.; Tiptsova, V.G.; Ivanov, V.M.

    1978-01-01

    The basic methods for extracting thorium from monazites and determining it photometrically and complexometrically are described. Monazite is decomposed by fusion with sodium peroxide, then thorium and the totality of lanthanides are precipitated in the form of oxalates. After the oxalates have been broken down, thorium is determined photometrically with the aid of arsenazo 1, quercetin of 1-2(-pyridylazo)-resorcin. It takes 25 to 30 minutes to photometrically determine Th in monazites with the aid of arsenazo 2 (error: 3 to 5%). Arsenazo 2 is recommended for analysis of monazites containing 20 to 30% of lanthanides. Arsenazo 3 permits determining Th in zircon and in Nb-containing materials. In this case, the determination is possible in strongly acidic solutions, the ratio of arsenazo 3 to Th being 7.5:1. Arsenazo 3 can also be used in determining trace amounts of Th (1x10 -5 to 1x10 -4 %) in rocks, as well as in extraction-photometric determination of Th traces. The dyed compound of Th with arsenazo 3 is extracted with isoamyl alcohol in the presence of diphenylguanidinium chloride and monochloroacetic acid. The method permits determining Th at 1:5x10 8 (0.002 g/ml) dilution. Also described is the iodate-complexometric method for determining Th

  1. 10th Workshop on Self-Organizing Maps

    CERN Document Server

    Schleif, Frank-Michael; Kaden, Marika; Lange, Mandy

    2014-01-01

    The book collects the scientific contributions presented at the 10th Workshop on Self-Organizing Maps (WSOM 2014) held at the University of Applied Sciences Mittweida, Mittweida (Germany, Saxony), on July 2–4, 2014. Starting with the first WSOM-workshop 1997 in Helsinki this workshop focuses on newest results in the field of supervised and unsupervised vector quantization like self-organizing maps for data mining and data classification.   This 10th WSOM brought together more than 50 researchers, experts and practitioners in the beautiful small town Mittweida in Saxony (Germany) nearby the mountains Erzgebirge to discuss new developments in the field of unsupervised self-organizing vector quantization systems and learning vector quantization approaches for classification. The book contains the accepted papers of the workshop after a careful review process as well as summaries of the invited talks.   Among these book chapters there are excellent examples of the use of self-organizing maps in agriculture, ...

  2. The Impact of Project-Based Learning on Minority Student Achievement: Implications for School Redesign

    Science.gov (United States)

    Cervantes, Bernadine; Hemmer, Lynn; Kouzekanani, Kamiar

    2015-01-01

    Project-Based Learning (PBL) serves as an instructional approach to classroom teaching and learning that is designed to engage students in the investigation of real-world problems to create meaningful and relevant educational experiences. The causal-comparative study compared 7th and 8th students who had utilized the PBL with a comparison group in…

  3. Exploring the Learning Mechanism in Educational Games

    OpenAIRE

    Kiili, Kristian; Ketamo, Harri

    2007-01-01

    The main aim of this paper is to evaluate the problem based gaming model that tries to explain the learning process in educational games. The model was studied through Geometry game aimed for pre-school children (N = 24). The game relays on learning by teaching approach and involves AI-engine modeling the human concept learning structures. The qualitative analyses were used to explore participants learning processes and gaming strategies. The results indicated that the model well describes th...

  4. Academic Training: Academic Training Programme 50th Anniversary Lectures

    CERN Multimedia

    Françoise Benz

    2004-01-01

    13, 14, 15 & 16 September From 16:30 hrs - Main Auditorium bldg. 500 50 years of research at CERN: from past to future Monday 13 September 50 years of research at CERN: from past to future (Accelerator) (1/4) K. Hubner / CERN-DSU A summary of the evolution of the CERN accelerator complex since the beginning will be given. The emphasis will be on the salient features and highlights and what has been learned at each stage in terms of accelerator physics and technology. Possible future options for CERN based on accelerators will be discussed. Tuesday 14 September 50 years of research at CERN: from past to future (Theory) (2/4) G. Veneziano / CERN-PH-TH Great developments in our understanding of fundamental physics, together with striking technological advances, have repeatedly changed the way CERN/TH has been operating during the past 50 years. I will outline the main 'revolutions' I have myself witnessed at CERN/TH since the mid sixties, and then dare to express expectations, hopes, and fears for how ...

  5. Lifelong Learning: Policies, Practices, and Programs.

    Science.gov (United States)

    Hatton, Michael J., Ed.

    The 26 articles in this book focus on lifelong learning policies, practices, and programs in 13 Asia Pacific countries. The following papers are included: "Half a Revolution: A Brief Survey of Lifelong Learning in New Zealand" (P. Methven and J. Hansen); "HRD in a Multicultural Workplace: The Need for Lifelong Learning" (M.…

  6. Promoting Learning Achievement, Problem Solving, and Learning Curiosity of High School Students: Empirical Thai Study of Self-directed Learning in Physics Course

    Directory of Open Access Journals (Sweden)

    Wittaya Worapun

    2017-11-01

    Full Text Available Three phases of this research were employed to study learning achievement, problem solving, and learning curiosity among 43 students in the 11th grade through self-directed learning in a Physics course. Research instruments included: a learning achievement test, a test of curiosity, observations using anecdotal evidence of curiosity, and a test of problem solving ability. The findings show that six components of self-directed learning were evident, i.e. principles and basic concepts, syntax, social system, principle of reaction, and support system. It was found that five main procedures of self-directed learning were applicable in a management model: diagnosis, strategies, growth in habit, taking action, and summarizing and assessing. Students gained in their learning achievement ; furthermore, their posttest scores in problem solving were greater than their pretest scores at .05 level of statistical significance.

  7. Investigating the Effectiveness of Case-based Learning Instruction on Students’ Understanding the Subject of Reaction Rate

    Directory of Open Access Journals (Sweden)

    Aysel Ünal SÜMEN

    2015-04-01

    Full Text Available This study has been carried out to determine the effectiveness of case-based learning related to reaction rate on students’ conceptual understanding and conceptual change. In this respect, a class of 11th grade students in an Anatolian High School in the center of Izmir city was chosen randomly as experimental group (n=26 and another as control group (n=22. Reaction rate unit was taught to the experimental group within case-based learning method, and to the control group through activities defined in Chemistry curriculum. Comprehension Test developed by Cakmakci (2005 was utilized as data collecting instrument. The Comprehension Test was applied simultaneously to both experimental and control groups before and after the teaching. The data collected via the Comprehension Test was analyzed in terms of both quantity and quality. As a result of the study, it was noted that there was a significant difference between the groups after the instruction in favor of the experimental group. Also, it was determined that case-based learning was more effective in promoting conceptual change and assuring higher level of conceptual understanding for students.

  8. Distributed Practice and Retrieval Practice in Primary School Vocabulary Learning

    NARCIS (Netherlands)

    N.A.M.C. Goossens (Nicole)

    2015-01-01

    markdownabstractThe aim of this thesis was to investigate whether particular memory strategies stemming from cognitive and educational psychology, enhance primary school vocabulary learning. Th e memory strategies investigated in this thesis were distributed practice and retrieval practice. Th e

  9. Positioning and Navigation: Services for Open Educational Practices

    NARCIS (Netherlands)

    Kalz, Marco

    2007-01-01

    Presentation given at the Special Session on Open Educational Resources and Practices at the 10th International Conference on Interactive Computer Aided Learning, Villach (Austria), 26 - 28 September 2007

  10. Conditioning Factors for Group Management in Blended Learning Scenarios

    NARCIS (Netherlands)

    Pérez-Sanagustín, Mar; Hernández-Leo, Davinia; Blat, Josep

    2009-01-01

    Pérez-Sanagustín, M., Hernández-Leo D., & Blat, J. (accepted). Conditioning Factors for Group Management in Blended Learning Scenarios. The 9th IEEE International Conference on Advanced Learning Technologies. July, 14-18, 2009, Riga, Latvia.

  11. Understanding and reducing student withdrawal in e-learning

    OpenAIRE

    Marko Radovan

    2012-01-01

    In this paper we address the problem of student dropout from e-learning programmes. The proponents of e-learning highlight several advantages of this type of education as compared to the traditional, such as greater openness and diversity of training materials, the ability to adjust the mode and speed of learning, and similar. Despite these advantages, an increasing number of programmes and acceptance of e-learning as a national strategy all around the world, e-learning providers also face th...

  12. 40 CFR 26.1118-26.1122 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false [Reserved] 26.1118-26.1122 Section 26.1118-26.1122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN... Exposure of Non-pregnant, Non-nursing Adults §§ 26.1118-26.1122 [Reserved] ...

  13. 40 CFR 26.1103-26.1106 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false [Reserved] 26.1103-26.1106 Section 26.1103-26.1106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN... Exposure of Non-pregnant, Non-nursing Adults §§ 26.1103-26.1106 [Reserved] ...

  14. Dissolution behaviour of 238U, 234U and 230Th deposited on filters from personal dosemeters.

    Science.gov (United States)

    Becková, Vera; Malátová, Irena

    2008-01-01

    Kinetics of dissolution of (238)U, (234)U and (230)Th dust deposited on filters from personal alpha dosemeters was studied by means of a 26-d in vitro dissolution test with a serum ultrafiltrate simulant. Dosemeters had been used by miners at the uranium mine 'Dolní Rozínka' at Rozná, Czech Republic. The sampling flow-rate as declared by the producer is 4 l h(-1) and the sampling period is typically 1 month. Studied filters contained 125 +/- 6 mBq (238)U in equilibrium with (234)U and (230)Th; no (232)Th series nuclides were found. Half-time of rapid dissolution of 1.4 d for (238)U and (234)U and slow dissolution half-times of 173 and 116 d were found for (238)U and (234)U, respectively. No detectable dissolution of (230)Th was found.

  15. Th1 and Th2 help for B cells

    DEFF Research Database (Denmark)

    Poudrier, J; Owens, T

    1995-01-01

    that IL-5 (125 U/ml) synergizes with Th1 cells to induce B cell responses to IL-2, that are maintained following T-cell removal, e.g. autonomous. Th1 help in the absence of IL-5 resulted in weak or undetectable responses following T cell removal. The mechanism of IL-5 synergy involved persistence of IL-2R...... anti-Ig did not circumvent the need for IL-5 for autonomous IL-2 responses. Consistent with the above, interaction with an IL-5-producing Th2 clone induced strong autonomous B cell responses to IL-2. Qualitative differences of Th2 help over that of Th1 may thus be attributable to their differential...

  16. In vitro Comparative Evaluation of Tensile Bond Strength of 6(th), 7(th) and 8(th) Generation Dentin Bonding Agents.

    Science.gov (United States)

    Kamble, Suresh S; Kandasamy, Baburajan; Thillaigovindan, Ranjani; Goyal, Nitin Kumar; Talukdar, Pratim; Seal, Mukut

    2015-05-01

    Newer dentin bonding agents were developed to improve the quality of composite restoration and to reduce time consumption in its application. The aim of the present study was to evaluate tensile bond strength of 6(th), 7(th) and 8(th) generation bonding agents by in vitro method. Selected 60 permanent teeth were assigned into 20 in each group (Group I: 6(th) generation bonding agent-Adper SE plus 3M ESPE, Group II: 7(th) generation bonding agent-G-Bond GC Corp Japan and Group III: 8(th) generation dentin adhesives-FuturaBond, DC, Voco, Germany). With high-speed diamond disc, coronal dentin was exposed, and selected dentin bonding agents were applied, followed by composite restoration. All samples were saved in saline for 24 h and tensile bond strength testing was done using a universal testing machine. The obtained data were tabulated and statistically analyzed using ANOVA test. The tensile bond strength readings for 6(th) generation bonding agent was 32.2465, for 7(th) generation was 31.6734, and for 8(th)-generation dentine bonding agent was 34.74431. The highest tensile bond strength was seen in 8(th) generation bonding agent compared to 6(th) and 7(th) generation bonding agents. From the present study it can be conclude that 8(th) generation dentine adhesive (Futura DC, Voco, Germany) resulted in highest tensile bond strength compared to 6(th) (Adper SE plus, 3M ESPE) and 7(th) generation (G-Bond) dentin bonding agents.

  17. Block Study: Learning About Your Local Community.

    Science.gov (United States)

    Eckbreth, Catherine

    Designed for 7th- and 8th-grade students, five lessons using a block of houses in an urban neighborhood help students learn about the history of a neighborhood, the owners of the houses, and the style and architectural features of the homes. Although this unit has been developed for a specific neighborhood, a similar block study could be conducted…

  18. The Contribution of Learning Outcomes for Listening to Creative Thinking Skills

    Science.gov (United States)

    Aldig, Ebru; Arseven, Ayla

    2017-01-01

    This study aims to examine teacher's opinions on the contribution of learning outcomes for listening defined in the Ministry of National Education's Turkish course curriculum for the 6th, 7th and 8th grades to the development of creative thinking skills. Mixed methods research design was adopted in the study. As the quantitative part of the study,…

  19. 11th Workshop on Self-Organizing Maps

    CERN Document Server

    Mendenhall, Michael; O'Driscoll, Patrick

    2016-01-01

    This book contains the articles from the international conference 11th Workshop on Self-Organizing Maps 2016 (WSOM 2016), held at Rice University in Houston, Texas, 6-8 January 2016. WSOM is a biennial international conference series starting with WSOM'97 in Helsinki, Finland, under the guidance and direction of Professor Tuevo Kohonen (Emeritus Professor, Academy of Finland). WSOM brings together the state-of-the-art theory and applications in Competitive Learning Neural Networks: SOMs, LVQs and related paradigms of unsupervised and supervised vector quantization. The current proceedings present the expert body of knowledge of 93 authors from 15 countries in 31 peer reviewed contributions. It includes papers and abstracts from the WSOM 2016 invited speakers representing leading researchers in the theory and real-world applications of Self-Organizing Maps and Learning Vector Quantization: Professor Marie Cottrell (Universite Paris 1 Pantheon Sorbonne, France), Professor Pablo Estevez (University of Chile and ...

  20. Motivating Students for Project-based Learning for Application of Research Methodology Skills.

    Science.gov (United States)

    Tiwari, Ranjana; Arya, Raj Kumar; Bansal, Manoj

    2017-12-01

    Project-based learning (PBL) is motivational for students to learn research methodology skills. It is a way to engage and give them ownership over their own learning. The aim of this study is to use PBL for application of research methodology skills for better learning by encouraging an all-inclusive approach in teaching and learning rather than an individualized tailored approach. The present study was carried out for MBBS 6 th - and 7 th -semester students of community medicine. Students and faculties were sensitized about PBL and components of research methodology skills. They worked in small groups. The students were asked to fill the student feedback Questionnaire and the faculty was also asked to fill the faculty feedback Questionnaire. Both the Questionnaires were assessed on a 5 point Likert scale. After submitted projects, document analysis was done. A total of 99 students of the 6 th and 7 th semester were participated in PBL. About 90.91% students agreed that there should be continuation of PBL in subsequent batches. 73.74% felt satisfied and motivated with PBL, whereas 76.77% felt that they would be able to use research methodology in the near future. PBL requires considerable knowledge, effort, persistence, and self-regulation on the part of the students. They need to devise plans, gather information evaluate both the findings, and their approach. Facilitator plays a critical role in helping students in the process by shaping opportunity for learning, guiding students, thinking, and helping them construct new understanding.

  1. Reading across Workplace Learning Research to Build Dialogue

    Science.gov (United States)

    Sawchuk, Peter H.

    2010-01-01

    The field of workplace learning scholarship in Western countries is reviewed. First, the emergence of workplace learning scholarship is discussed historically for its relation to the emergence and ongoing development of capitalism beginning from early thought on markets and productivity, 20th century scientific management, industrialism and…

  2. The Th1/Th2/Th17/Treg paradigm induced by stachydrine hydrochloride reduces uterine bleeding in RU486-induced abortion mice.

    Science.gov (United States)

    Li, Xia; Wang, Bin; Li, Yuzhu; Wang, Li; Zhao, Xiangzhong; Zhou, Xianbin; Guo, Yuqi; Jiang, Guosheng; Yao, Chengfang

    2013-01-09

    The Th1/Th2/Th17/Treg paradigm plays an important role in achieving maternal-fetal immunotolerance and participates in RU486-induced abortion. Excessive uterine bleeding is the most common side effect of RU486-induced abortion; however, its etiopathogenesis has not been fully understood. Therefore, elucidating the correlation between the Th1/Th2/Th17/Treg paradigm and the volume of uterine bleeding may offer novel therapeutic target for reducing uterine bleeding in RU486-induced abortion. Leonurus sibiricus has been used in clinics to reduce postpartum hemorrhage with low toxicity and high efficiency; however, the effective constituents and therapeutic mechanism have not been described. Stachydrine hydrochloride is the main constituent of L. sibiricus, therefore L. sibiricus is regarded as a candidate for reducing uterine bleeding in RU486-induced abortion mice by regulating the Th1/Th2/Th17/Treg paradigm. The purpose of this study was to determine the Th1/Th2/Th17/Treg paradigm in uterine bleeding of RU486-induced abortion mice and to elucidate the immunopharmacologic effects of stachydrine hydrochloride on inducing the Th1/Th2/Th17/Treg paradigm in reducing the uterine bleeding volume in RU486-induced abortion mice. To investigate the Th1/Th2/Th17/Treg paradigm in uterine bleeding during RU486-induced abortion mice, pregnant BALB/c mice were treated with high- and low-dose RU486 (1.5mg/kg and 0.9 mg/kg, respectively), and the serum progesterone (P(4)) protein level, uterine bleeding volume, and proportions of Th1/Th2/Th17/Treg cells in mice at the maternal-fetal interface were detected by ELISA assay, alkaline hematin photometric assay, and flow cytometry, respectively. To determine the regulatory effect of stachydrine hydrochloride on the Th1/Th2/Th17/Treg paradigm in vitro, splenocytes of non-pregnant mice were separated and treated with P(4,) RU486, and/or stachydrine hydrochloride (10(-5)M, 10(-4)M, and 10(-3)M, respectively). The proportions of Th1/Th2/Th17

  3. 6th International Parallel Tools Workshop

    CERN Document Server

    Brinkmann, Steffen; Gracia, José; Resch, Michael; Nagel, Wolfgang

    2013-01-01

    The latest advances in the High Performance Computing hardware have significantly raised the level of available compute performance. At the same time, the growing hardware capabilities of modern supercomputing architectures have caused an increasing complexity of the parallel application development. Despite numerous efforts to improve and simplify parallel programming, there is still a lot of manual debugging and  tuning work required. This process  is supported by special software tools, facilitating debugging, performance analysis, and optimization and thus  making a major contribution to the development of  robust and efficient parallel software. This book introduces a selection of the tools, which were presented and discussed at the 6th International Parallel Tools Workshop, held in Stuttgart, Germany, 25-26 September 2012.

  4. Activated rat hepatic stellate cells influence Th1/Th2 profile in vitro.

    Science.gov (United States)

    Xing, Zhi-Zhi; Huang, Liu-Ye; Wu, Cheng-Rong; You, Hong; Ma, Hong; Jia, Ji-Dong

    2015-06-21

    To investigate the effects of activated rat hepatic stellate cells (HSCs) on rat Th1/Th2 profile in vitro. Growth and survival of activated HSCs and CD4(+) T lymphocytes cultured alone or together was assessed after 24 or 48 h. CD4(+) T lymphocytes were then cultured with or without activated HSCs for 24 or 48 h and the proportion of Th1 [interferon (IFN)-γ(+)] and Th2 [interleukin (IL)-4(+)] cells was assessed by flow cytometry. Th1 and Th2 cell apoptosis was assessed after 24 h of co-culture using a caspase-3 staining procedure. Differentiation rates of Th1 and Th2 cells from CD4(+) T lymphocytes that were positive for CD25 but did not express IFN-γ or IL-4 were also assessed after 48 h of co-culture with activated HSCs. Galectin-9 expression in HSCs was determined by immunofluorescence and Western blotting. ELISA was performed to assess galectin-9 secretion from activated HSCs. Co-culture of CD4(+) T lymphocytes with activated rat HSCs for 48 h significantly reduced the proportion of Th1 cells compared to culture-alone conditions (-1.73% ± 0.71%; P Th1/Th2 ratio was significantly decreased (-0.44 ± 0.13; P Th1 cells was decreased (-65.71 ± 9.67; P Th1 (12.27% ± 0.99%; P Th1 cell apoptosis rate was significantly higher than in Th2 cells (P Th1 and Th2 cells; however, the increase in the proportion of Th2 cells was significantly higher than that of Th1 cells (1.85% ± 0.48%; P Th1/Th2 profile, inhibiting the Th1 response and enhancing the Th2 response, and this may be a novel pathway for liver fibrogenesis.

  5. The role of Th1 and Th17 cells in glomerulonephritis.

    Science.gov (United States)

    Azadegan-Dehkordi, Fatemeh; Bagheri, Nader; Shirzad, Hedayatollah; Rafieian-Kopaei, Mahmoud

    2015-04-01

    T helper (Th) cells as an important part of the immune is responsible for elimination of invading pathogens. But, if Th cell responses are not regulated effectively, the autoimmune diseases might develop. The Th17 subset usually produces interleukin-17A which in experimental models of organ-specific autoimmune inflammation is very important. Directory of open access journals (DOAJ), Google Scholar, Embase, Scopus, PubMed and Web of Science have been searched. Fifty-six articles were found and searched. In the present review article, we tried to summarize the recently published data about characteristics and role of Th1 and Th17 cells and discuss in detail, the potential role of these T helpers immune responses in renal inflammation and renal injury, focusing on glomerulonephritis. Published papers in animal and human studies indicated that autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, classically believed to be Th1-mediated, are mainly derived from a Th17 immune response. Identification of the Th17 subgroup has explained seemingly paradoxical observations and improved our understanding of immune-mediated inflammatory responses. Secretion of IL-17A, as well as IL-17F, IL-21, IL-22, suggests that Th17 subset may play a crucial role as a pleiotropic pro-inflammatory Th subset. There is experimental evidence to support the notion that Th1 and Th17 cells contribute to kidney injury in renal inflammatory diseases like glomerulonephritis.

  6. 6th International Conference on Practical Applications of Computational Biology & Bioinformatics

    CERN Document Server

    Luscombe, Nicholas; Fdez-Riverola, Florentino; Rodríguez, Juan; Practical Applications of Computational Biology & Bioinformatics

    2012-01-01

    The growth in the Bioinformatics and Computational Biology fields over the last few years has been remarkable.. The analysis of the datasets of Next Generation Sequencing needs new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Also Systems Biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. This book presents the results of the  6th International Conference on Practical Applications of Computational Biology & Bioinformatics held at University of Salamanca, Spain, 28-30th March, 2012 which brought together interdisciplinary scientists that have a strong background in the biological and computational sciences.

  7. HSCI2014: booklet of the 11th International Conference on Hands-on Science

    OpenAIRE

    Costa, Manuel F. M., ed. lit.; Pombo, José Miguel Marques, ed. lit.; Vázquez Dorrío, José Benito, ed. lit.; International Conference on Hands-on Science, 11, Aveiro, 2014

    2014-01-01

    The core topic of the 11th Hands-on Science Conference is "Science Education with and for Society" As we all know it is the Society that sets the requirements rules and procedures of Education. It is Society that defines what citizens must learn in what concern either concepts and or competencies, and how this learning can, must in fact…, take place. Society is the ensemble of all of us citizens and of all the structures tangible and intangible we create and created along the y...

  8. What about Th1/Th2 in cutaneous leishmaniasis vaccine discovery?

    Directory of Open Access Journals (Sweden)

    Campos-Neto A.

    2005-01-01

    Full Text Available The T helper cell type 1 (Th1 response is essential to resist leishmaniasis, whereas the Th2 response favors the disease. However, many leishmanial antigens, which stimulate a Th1 immune response during the disease or even after the disease is cured, have been shown to have no protective action. Paradoxically, antigens associated with an early Th2 response have been found to be highly protective if the Th1 response to them is generated before infection. Therefore, finding disease-associated Th2 antigens and inducing a Th1 immune response to them using defined vaccination protocols is an interesting unorthodox alternative approach to the discovery of a leishmania vaccine.

  9. The Effect of Active Learning Approach on Attitudes of 7th Grade Students

    Science.gov (United States)

    Demirci, Cavide

    2017-01-01

    Active learning is a student's active impact on learning and a student's involvement in the learning process which allows students to focus on creating knowledge with an emphasis on skills such as analytical thinking, problem-solving and meta-cognitive activities that develop students' thinking. The main purpose of this study is to determine…

  10. Student Involvement in Learning and School Achievement.

    Science.gov (United States)

    Anderson, Lorin W.

    The purpose of the study was to investigate the relationship between selected student characteristics, student involvement in learning, and achievement. Both naturalistic (n = 28, 27) and experimental studies were conducted. In the experimental study, two classes (n = 29, 26) learned a sequence of matrix arithmetic by mastery learning strategies.…

  11. Determination of 228Th, 230Th, and 232Th in environmental samples from uranium mining and milling operations

    International Nuclear Information System (INIS)

    Durham, R.W.; Joshi, S.R.

    1979-01-01

    A method is described for the determination of 228 Th, 230 Th, and 232 Th in environmental samples from uranium mining and milling operations. The analytical procedure is based on the direct determination of 228 Th in the sample by high resolution γ-spectrometry followed by extraction and purification of the thorium fraction using high molecular weight amines and an anion-exchange technique, respectively, prior to α-spectrometry to determine isotopic ratios. The lowest level of detection for each thorium isotope is 0.01 pCi/g for solid samples and 20 pCi/l for aqueous samples. Replicate analyses of a typical mine waste stream gave a standard deviation of +-3% for 228 Th. Standard deviations of the 230 Th and 232 Th increased to +-11% apparently due to traces of 210 Po interfering in the α-spectrometry. (author)

  12. Implementation of Case-Based Instruction on Electrochemistry at the 11th Grade Level

    Science.gov (United States)

    Tarkin, Aysegul; Uzuntiryaki-Kondakci, Esen

    2017-01-01

    This study aims to compare the effectiveness of case-based instruction over traditional instruction in improving 11th grade students' understanding of electrochemistry concepts, attitudes toward chemistry, chemistry self-efficacy beliefs, and motivation to learn chemistry. In total, 113 students (47 males and 66 females) from three high schools…

  13. Learning Analytics: drivers, developments and challenges

    Directory of Open Access Journals (Sweden)

    Rebecca Ferguson

    2014-12-01

    Full Text Available Learning analytics is a significant area of Technology-Enhanced Learning (TEL that has emerged during the last decade. This review of the field begins with an examination of the technological, educational and political factors that have driven the development of analytics in educational settings. It goes on to chart the emergence of learning analytics, including their origins in the 20th century, the development of data-driven analytics, the rise of learning-focused perspectives and the influence of national economic concerns. It next focuses on the relationships between learning analytics, educational data mining and academic analytics. Finally, it examines developing areas of learning analytics research, and identifies a series of future challenges.

  14. A Problem-Based Learning Scenario That Can Be Used in Science Teacher Education

    Science.gov (United States)

    Sezgin Selçuk, Gamze

    2015-01-01

    The purpose of this study is to introduce a problem-based learning (PBL) scenario that elementary school science teachers in middle school (5th-8th grades) can use in their in-service training. The scenario treats the subjects of heat, temperature and thermal expansion within the scope of the 5th and 6th grade science course syllabi and has been…

  15. Proceedings of the 6th Computer Science On-line Conference 2017

    CERN Document Server

    Senkerik, Roman; Oplatkova, Zuzana; Prokopova, Zdenka; Silhavy, Petr

    2017-01-01

    This book presents new methods and approaches to real-world problems as well as exploratory research that describes novel artificial intelligence applications, including deep learning, neural networks and hybrid algorithms. This book constitutes the refereed proceedings of the Artificial Intelligence Trends in Intelligent Systems Section of the 6th Computer Science On-line Conference 2017 (CSOC 2017), held in April 2017. .

  16. Elevated Ratio of Th17 Cell-Derived Th1 Cells (CD161(+)Th1 Cells) to CD161(+)Th17 Cells in Peripheral Blood of Early-Onset Rheumatoid Arthritis Patients.

    Science.gov (United States)

    Kotake, Shigeru; Nanke, Yuki; Yago, Toru; Kawamoto, Manabu; Kobashigawa, Tsuyoshi; Yamanaka, Hisashi

    2016-01-01

    Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the destruction of articular cartilage and bone with elevated levels of proinflammatory cytokines. It has been reported that IL-17 and Th17 cells play important roles in the pathogenesis of RA. Recently, plasticity in helper T cells has been demonstrated; Th17 cells can convert to Th1 cells. It remains to be elucidated whether this conversion occurs in the early phase of RA. Here, we tried to identify Th17 cells, Th1 cells, and Th17 cell-derived Th1 cells (CD161(+)Th1 cells) in the peripheral blood of early-onset RA patients. We also evaluated the effect of methotrexate on the ratio of Th17 cells in early-onset RA patients. The ratio of Th17 cell-derived Th1 cells to CD161(+)Th17 cells was elevated in the peripheral blood of early-onset RA patients. In addition, MTX reduced the ratio of Th17 cells but not Th1 cells. These findings suggest that IL-17 and Th17 play important roles in the early phase of RA; thus, anti-IL-17 antibodies should be administered to patients with RA in the early phase.

  17. UK experience with ICRP26 and ICRP30

    International Nuclear Information System (INIS)

    Dray, C.H.

    1991-01-01

    ICRP26 was adopted in January 1977 which took into account information emerging since the adoption of ICRP9 in September 1969 and specified the basic criteria for dose limitation which still apply today. ICRP30 defines the limits for intakes for radionuclides for workers, and enables the health physicist and regulatory bodies to make appropriate limits for annual intake, air contamination etc, to comply requirements of dose-equivalent commitment and committed dose equivalent. The publication of ICRP26 is reflected in European Communities directive 80/836/Euratom. Council Directive of 15th July 1980 amending the Directive laying down the basic safety standards for the health protection of general public and workers against the dangers of ionizing radiations. This document being required the member states to bring the requirements of the directive within their legislation. In the United Kingdom this was accomplished by the publication of the Ionizing Radiations Regulations 1985

  18. ARLearn - Open source mobile application platform for learning

    NARCIS (Netherlands)

    Börner, Dirk; Ternier, Stefaan; Klemke, Roland; Schmitz, Birgit; Kalz, Marco; Tabuenca, Bernardo; Specht, Marcus

    2013-01-01

    Börner, D., Ternier, S., Klemke, R., Schmitz, B., Kalz, M., Tabuenca, B., & Specht, M. (2013). ARLearn - Open source mobile application platform for learning. In D. Hernández-Leo et al. (Eds.), Scaling up Learning for Sustained Impact. Proceedings of the 8th European Conference on Technology

  19. Effect of ambulatory medicine tutorial on clinical performance of 5th year medical students.

    Science.gov (United States)

    Phisalprapa, Pochamana; Pandejpong, Denla

    2013-02-01

    The present study provided a group learning activity called "Ambulatory Medicine Tutorial-AMT" for 5th year medical students in order to facilitate learning experience at ambulatory setting and to improve medical students' clinical performance. This research aimed specifically to study the effect of AMT. Two groups of twenty 5th-year medical students were enrolled during their ambulatory medicine blocks. Each medical student was assigned to have 8 ambulatory sessions. AMT was assigned to one group while the other group only used conventional learning activity. At the end of the present study, total internal medicine scores, patient satisfaction surveys, and data on average time spent on each clinical encounter were collected and compared. The AMT group received a higher total internal medicine score as compared to the conventional group (76.2 +/- 3.6 vs. 72.9 +/- 2.8, p = 0.003). The AMT group could reduce average time spent on each clinical encounter within their first-6 ambulatory sessions while the conventional group could acquire the same skill later in their last 2 ambulatory sessions. There was no significant difference found on comparing patient satisfaction scores between the 2 groups. AMT helped improving medical students' outcomes as shown from higher total internal medicine score as well as quicker improvement during real-life clinical encounters, AMT could be a good alternative learning activity for medical students at ambulatory setting.

  20. Knowledge and Learning in Engineering Practice

    DEFF Research Database (Denmark)

    Buch, Anders

    2007-01-01

    , this chapter discusses the cencept of learning and purports to theorize learning in a Social Theory of Learning (STL). The attempt to reconstruct learning in an STL addresses three main issues: an STL must try to specify the subject-world relationship, describe the 'mechanism' of learning, and identify......During the 20th century, traditional epistemological theories of knowledge have been under siege. In recent years, efforts have been made to reconstruct the concept of 'knowledge' to emphasize its contextual, situated and social character. Drawing on the results and methods of these efforts...... the 'telos' of learning. This attempt will in fact give answers to three fundamental questions: 1) What is learning? 2) How do we learn? and 3) Why do we learn? These questions are discussed in relation to engineering practices of getting to know and learning....

  1. Th1-Th17 Ratio as a New Insight in Rheumatoid Arthritis Disease.

    Science.gov (United States)

    Bazzazi, Hadi; Aghaei, Mehrdad; Memarian, Ali; Asgarian-Omran, Hossein; Behnampour, Nasser; Yazdani, Yaghoub

    2018-02-01

    The Th17, Th1 and dual Th17/Th1 cells are important players in rheumatoid arthritis (RA) disease. To assess their roles, the frequency and impact of these cells were investigated in patients with different disease activity. In 14 new cases and 41 established RA patients in comparison with 22 healthy controls, the percentages of Th17, Th1 and dual Th17/Th1 cells were determined by flow-cytometry and their correlations were investigated with disease activity score (DAS28). Moreover, serum levels of IL-6 and IL-17 as inducer and functional cytokines for Th17 were investigated. Finally, serum levels of anti citrullinated protein antibody (ACPA) and rheumatoid factor (RF) were assessed. Percentage of Th17 cells in RA patients were increased in comparison with healthy controls (pTh1 cells in RA patients were less than healthy group (pTh17/Th1 cell only in new cases of RA were more than healthy control groups (pTh1/Th17 ratio in RA patients is statistically different with healthy control group (pTh1/Th17 ratio in RA patient suggested a new paradigm in the field of autoimmune disease and indicated that imbalance or plasticity between these subsets can be important in progress, diagnosis and therapy of RA disease.

  2. IMS Learning Design Support for the Formalization of Collaborative Learning Patterns

    NARCIS (Netherlands)

    Hernández-Leo, Davinia; Asensio-Pérez, Juan; Dimitriadis, Yannis

    2004-01-01

    The paper was granted with "an ICALT Best Paper Award". Appears in Proceedings of the 4th International Conference on Advanced Learning Technologies (ICALT04), pp. 350-354, Joensuu, Finland, 31 Aug - 1 Sep 2004. (source link).

  3. Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells.

    Science.gov (United States)

    Riaz, Tahira; Sollid, Ludvig Magne; Olsen, Ingrid; de Souza, Gustavo Antonio

    2016-03-01

    T-helper cells are differentiated from CD4+ T cells and are traditionally characterized by inflammatory or immunosuppressive responses in contrast to cytotoxic CD8+ T cells. Mass-spectrometry studies on T-helper cells are rare. In this study, we aimed to identify the proteomes of human Th1 and Th1/Th17 clones derived from intestinal biopsies of Crohn's disease patients and to identify differentially expressed proteins between the two phenotypes. Crohn's disease is an inflammatory bowel disease, with predominantly Th1- and Th17-mediated response where cells of the "mixed" phenotype Th1/Th17 have also been commonly found. High-resolution mass spectrometry was used for protein identification and quantitation. In total, we identified 7401 proteins from Th1 and Th1/Th17 clones, where 334 proteins were differentially expressed. Major differences were observed in cytotoxic proteins that were overrepresented in the Th1 clones. The findings were validated by flow cytometry analyses using staining with anti-granzyme B and anti-perforin and by a degranulation assay, confirming higher cytotoxic features of Th1 compared with Th1/Th17 clones. By testing a larger panel of T-helper cell clones from seven different Crohn's disease patients, we concluded that only a subgroup of the Th1 cell clones had cytotoxic features, and these expressed the surface markers T-cell-specific surface glycoprotein CD28 and were negative for expression of natural killer group 2 member D. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  4. Modelo natural de dicotomía TH1-TH2: La enfermedad de Hansen Th1-TH2 balance. Natural model: Hansen'disease

    Directory of Open Access Journals (Sweden)

    N. L Vaquero

    2010-09-01

    Full Text Available La enfermedad de Hansen producida por el Mycobacterium leprae, es una enfermedad infecciosa cuyo amplio espectro clínico e inmunopatológico se correlaciona con los diferentes patrones de respuesta Th1/Th2. La activación preferencial de esas subpoblaciones de linfocitos T CD4 juega un rol importante en su patogenia y constituye un modelo natural de esa dicotomía de la respuesta inmune. Ambas formas polares de la lepra presentan un perfil definido de secreción de citoquinas: Th1 (IL2 e IFN? en el polo tuberculoide y Th2 (IL4, IL5, IL10 en el polo lepromatoso. En el primer caso, la respuesta celular adecuada estimula la activación macrofágica y lleva a la destrucción del bacilo. Las lesiones son escasas y limitadas a la piel y nervios periféricos. En el segundo en cambio, la respuesta celular es casi nula y los bacilos se multiplican descontroladamente dentro de los macrófagos, llevando a la diseminación de las lesiones y afectación de otros órganos. La inmunidad humoral está exacerbada y hay un alto nivel de anticuerpos que no pueden eliminar el germen intracelular. Los factores que determinan la diferenciación hacia una respuesta Th1 ó Th2 no se han esclarecido totalmente. Se han postulado varias hipótesis que hacen referencia a factores genéticos, prevalencia de citoquinas en el microambiente celular, disfunción macrofágica; alteración en los receptores Toll de la inmunidad innata, en la expresión de moléculas coestimulatorias, etc En los últimos años se han descubierto nuevas subpoblaciones de linfocitos, (CD4+ CD25+, Tr1, Th3 y Th17 que estarían implicadas en la desregulación de estas respuestas inmunes.Hansen' disease, caused by Mycobacterium leprae, is an infectious illness whose wide clinical and immunopathologic spectrum correl with different Th1/Th2 responses patterns. The prefferencial activation of the CD4 T cells subset play an important rol in it's pathogenia and provides a natural model of that balance

  5. International Workshop on Evidence-Based Technology Enhanced Learning

    CERN Document Server

    Gennari, Rosella; Marenzi, Ivana; Prieta, Fernando; Rodríguez, Juan

    2012-01-01

    Research on Technology Enhanced Learning (TEL) investigates how information and communication technologies can be designed in order to support pedagogical activities. The workshop proceedings collects contributions concerning evidence based TEL systems, like their design following EBD principles as well as studies or best practices that educators, education stakeholders or psychologists used to diagnose or improve their students' learning skills, including students with specific difficulties. The international ebTEL’12 workshop wants to be a forum in which TEL researchers and practitioners alike can discuss ideas, projects, and lessons related to ebTEL. The workshop takes place in Salamanca, Spain, on March 28th-30th 2012.  

  6. Report on the 19th SPACE Conference = 10. mednarodna konferenca SPACE

    Directory of Open Access Journals (Sweden)

    Rune Gulev

    2008-06-01

    Full Text Available The 19th international space (European Network for Business Studies and Languages conference that recently took place in Spain provided valuable insight into several areas of interest. Most notably, methods on how to successfully enhance the internationalization of higher learning institutions were shared through mobility and joint degrees programs. Furthermore, the conference provided an academic forum for a highly professional and earnest discourse on pertinent topics of relevance for higher learning institutions, which this year pivoted around intercultural awareness and dialogue. In sum, the space network provides a wealth of academic and administrative advantages that the academic sphere could greatly benefit from.

  7. The didactic situation in geometry learning based on analysis of learning obstacles and learning trajectory

    Science.gov (United States)

    Sulistyowati, Fitria; Budiyono, Slamet, Isnandar

    2017-12-01

    This study aims to design a didactic situation based on the analysis of learning obstacles and learning trajectory on prism volume. The type of this research is qualitative and quantitative research with steps: analyzing the learning obstacles and learning trajectory, preparing the didactic situation, applying the didactic situation in the classroom, mean difference test of problem solving ability with t-test statistic. The subjects of the study were 8th grade junior high school students in Magelang 2016/2017 selected randomly from eight existing classes. The result of this research is the design of didactic situations that can be implemented in prism volume learning. The effectiveness of didactic situations that have been designed is shown by the mean difference test that is the problem solving ability of the students after the application of the didactic situation better than before the application. The didactic situation that has been generated is expected to be a consideration for teachers to design lessons that match the character of learners, classrooms and teachers themselves, so that the potential thinking of learners can be optimized to avoid the accumulation of learning obstacles.

  8. Determination of 228Th, 226Ra and 40K in Soil Using In-Situ GammaSpectrometer

    International Nuclear Information System (INIS)

    Bunawas; Wahyudi; Syarbaini; Untara

    2000-01-01

    Determination of natural radionuclide in latosol soil at six locationsaround PPTN Serpong by using Inspector portable gamma spectrometer with highpurity Germanium detector (HPGe) which has 26% relative efficiency had beenobtained. Radionuclides data of 228 Th, 226 Ra and 40 K were obtained in4 hours, shorter than laboratories analysis which needed 3 weeks. Thedifferences between in-situ measurement and laboratory were 3.6% to 56.2% forsix conditions of soil measured. According to the specific activity dataanalysis using statistic hypothesis, the result shows that the activity of 228 Th and 226 Ra are independent on location, but 40 K is dependent onlocation. (author)

  9. Medical Student Perceptions of the Learning Environment in Medical School Change as Students Transition to Clinical Training in Undergraduate Medical School.

    Science.gov (United States)

    Dunham, Lisette; Dekhtyar, Michael; Gruener, Gregory; CichoskiKelly, Eileen; Deitz, Jennifer; Elliott, Donna; Stuber, Margaret L; Skochelak, Susan E

    2017-01-01

    Phenomenon: The learning environment is the physical, social, and psychological context in which a student learns. A supportive learning environment contributes to student well-being and enhances student empathy, professionalism, and academic success, whereas an unsupportive learning environment may lead to burnout, exhaustion, and cynicism. Student perceptions of the medical school learning environment may change over time and be associated with students' year of training and may differ significantly depending on the student's gender or race/ethnicity. Understanding the changes in perceptions of the learning environment related to student characteristics and year of training could inform interventions that facilitate positive experiences in undergraduate medical education. The Medical School Learning Environment Survey (MSLES) was administered to 4,262 students who matriculated at one of 23 U.S. and Canadian medical schools in 2010 and 2011. Students completed the survey at the end of each year of medical school as part of a battery of surveys in the Learning Environment Study. A mixed-effects longitudinal model, t tests, Cohen's d effect size, and analysis of variance assessed the relationship between MSLES score, year of training, and demographic variables. After controlling for gender, race/ethnicity, and school, students reported worsening perceptions toward the medical school learning environment, with the worst perceptions in the 3rd year of medical school as students begin their clinical experiences, and some recovery in the 4th year after Match Day. The drop in MSLES scores associated with the transition to the clinical learning environment (-0.26 point drop in addition to yearly change, effect size = 0.52, p effect size = 0.14, p work-life balance and informal student relationships. There was some, but not complete, recovery in perceptions of the medical school learning environment in the 4th year. Insights: Perceptions of the medical school learning

  10. Analysis of Primary School Student's Science Learning Anxiety According to Some Variables

    Science.gov (United States)

    Karakaya, Ferhat; Avgin, Sakine Serap; Kumperli, Ethem

    2016-01-01

    On this research, it is analyzed if the science learning anxiety level shows difference according to variables which are gender, grade level, science lesson grade, mother education, father education level. Scanning Design is used for this study. Research working group is consisted of 294 primary school from 6th, 7th and 8th graders on 2015-2016…

  11. Engaging 5th/6th Graders in Representations of Change Over Time in the Context of Adaptations to Climate Change in the Gulf of Maine

    Science.gov (United States)

    Peake, L.; Young Morse, R.

    2017-12-01

    Since 2005, the Gulf of Maine Research Institute has brought 70% of Maine's 5th/6th grade cohort annually to our marine research lab for a 2.5-hour exploration of ecosystem complexity. Using a digital platform, tools of science, and live marine species, students consider the interconnections among key Gulf of Maine species while experiencing the process of authentic marine research. With funding from NASA, we are renovating the program's learning content, underlying technology, and physical interfaces to leverage NASA data sets. The new experience will emphasize development of students' data skills as they investigate the impacts of climate change in the Gulf of Maine. To do this, students will explore representations of rising ocean temperatures and connect that to representations of changes in the populations of key species like lobster and black sea bass. Past experience suggests the abstraction and synthesis required to make meaning from data visualizations is extremely challenging for this age student. We will report on an early round of informal testing with 250+ students to understand their ability to extract meaning from geospatial and graphical representations of change over time. We will also report on experiments that will be conducted in Fall 2017 to understand the kinds of informal learning experiences, and the sequences of data representations, that best support growth in students' ability to interpret a range of representations. Finally, we will discuss the project's work to extend the learning experiences 1) back into the classroom, including through citizen science; and 2) out to regional science centers for adaptation to investigations of local climate impacts.

  12. Thèses de doctorat soutenues en 2007

    Directory of Open Access Journals (Sweden)

    2008-05-01

    Full Text Available Gérard Journée, « Rien ne saurait naître de rien ». L’émergence du problème de l’être dans la philosophie préplatonicienne.Thèse soutenue le 26 janvier 2007 Composition du jury : Michel Crubellier, Professeur à l'Université de Lille 3.François De Gandt, Professeur à l'Université de Lille 3.Paul Demont, Professeur à l'Université de Paris IV.Pierre-Marie Morel, Professeur à l'Université de Paris I.Malcolm Schofield, Professeur à l'Université de Cambridge.André Laks, Professeur à l'Université de...

  13. Preparation and characterization of some pyridine-2,6-dicarboxylato thorium(IV) complexes

    Energy Technology Data Exchange (ETDEWEB)

    Degetto, S; Baracco, L [Consiglio Nazionale delle Ricerche, Padua (Italy). Lab. di Chimica e Tecnologia dei Radioelementi; Graziani, R [Padua Univ. (Italy). Istituto di Chimica Generale ed Inorganica; Celon, E [Padua Univ. (Italy). Istituto di Chimica Organica

    1978-12-01

    The preparation of complexes of pyridine-2,6-dicarboxylic acid (H/sub 2/PDC) with thorium(IV) is reported and discussed. The reactivity of Th(PDC)/sub 2/(H/sub 2/O)/sub 4/ was tested by preparing adducts with some neutral ligands. The complexes were characterized by i.r. spectroscopy, elemental analysis and thermal behaviour. Preliminary information on the structure obtained by x-ray analysis is also reported.

  14. 8th Chinese Conference on The Semantic Web and Web Science

    CERN Document Server

    Du, Jianfeng; Wang, Haofen; Wang, Peng; Ji, Donghong; Pan, Jeff Z; CSWS 2014

    2014-01-01

    This book constitutes the thoroughly refereed papers of the 8th Chinese Conference on The Semantic Web and Web Science, CSWS 2014, held in Wuhan, China, in August 2014. The 22 research papers presented were carefully reviewed and selected from 61 submissions. The papers are organized in topical sections such as ontology reasoning and learning; semantic data generation and management; and semantic technology and applications.

  15. Processes of Learning with Regard to Students’ Learning Difficulties in Mathematics

    Directory of Open Access Journals (Sweden)

    Amalija Zakelj

    2014-06-01

    Full Text Available In the introduction, we write about the process of learning mathematics: the development of mathematical concepts, numerical and spatial imagery on reading and understanding of texts, etc. The central part of the paper is devoted to the study, in which we find that identifying the learning processes associated with learning difficulties of students in mathematics, is not statistically significantly different between primary school teachers and teachers of mathematics. Both groups expose the development of numerical concepts, logical reasoning, and reading and understanding the text as the ones with which difficulties in learning mathematics appear the most frequently. All the processes of learning that the teachers assessed as the ones that represent the greatest barriers to learning have a fairly uniform average estimates of the degree of complexity, ranging from 2.6 to 2.8, which is very close to the estimate makes learning very difficult.

  16. 15th IEEE International Conference on Intelligent Engineering Systems

    CERN Document Server

    Živčák, Jozef; Aspects of Computational Intelligence Theory and Applications

    2013-01-01

    This volume covers the state-of-the art of the research and development in various aspects of computational intelligence and gives some perspective directions of development. Except the traditional engineering areas that contain theoretical knowledge, applications, designs and projects, the book includes the area of use of computational intelligence in biomedical engineering. „Aspects of Computational Intelligence: Theory and Applications” is a compilation of carefully selected extended papers written on the basis of original contributions presented at the 15th IEEE International Conference on Intelligent Engineering Systems 2011, INES 2011 held at June 23.-26. 2011 in AquaCity Poprad, Slovakia.    

  17. Learning Strategies of Physics Teacher Candidates: Relationships with Physics Achievement and Class Level

    Science.gov (United States)

    Selçuk, Gamze S.; Çalişkan, Serap; Erol, Mustafa

    2007-04-01

    Learning strategy concept was introduced in the education field from the development of cognitive psychology. Learning strategies are behaviors and thoughts that a learner engages in during learning which are intended to influence the learner's encoding process. Literature on learning strategies in physics field is very scarce. Participants of the research consist of teacher candidates (n=137) from 1st, 2nd, 3rd, 4th and 5th grade attending Department of Physics Education, Education Faculty of Buca, Dokuz Eylül University in Turkey. Data of this research was collected by ``Scale of Learning Strategies Usage in Physics'' (Cronbach's Alpha=0.93). Mean, Standard Deviation, Analysis of Variance were used to analyze the research data. This paper reports on teacher candidates' learning strategies used in physics education The paper investigates the relationships between learning strategies and physics achievement, class level. Some important outcomes of the research are presented, discussed and certain suggestions are made.

  18. Problems in the Deployment of Learning Networks In Small Organizations

    NARCIS (Netherlands)

    Shankle, Dean E.; Shankle, Jeremy P.

    2006-01-01

    Please, cite this publication as: Shankle, D.E., & Shankle, J.P. (2006). Problems in the Deployment of Learning Networks In Small Organizations. Proceedings of International Workshop in Learning Networks for Lifelong Competence Development, TENCompetence Conference. March 30th-31st, Sofia, Bulgaria:

  19. 6th year of the MEFANET conference brought new ideas for the education of future health professionals

    Directory of Open Access Journals (Sweden)

    Lenka Šnajdrová

    2013-05-01

    Full Text Available The 6th year of the MEFANET conference was held in Brno, Czech Republic, from Tuesday 27th to Wednesday 28th November 2012. This conference provides a regular opportunity for teachers and students from medical faculties from all over the Czech Republic and Slovakia to meet experts in health care informatics and providers of electronical support in the education. Apart from methodical and educational aspects of e-learning at medical faculties in general, this year’s conference has again dealt with the impact of this phenomenon on a specific medical specialty: a thematically focused symposium addressed the fields of orthopaedics, rheumatology and physiotherapy.

  20. Searching for Buried Treasure: Uncovering Discovery in Discovery-Based Learning

    Science.gov (United States)

    Chase, Kiera; Abrahamson, Dor

    2018-01-01

    Forty 4th and 9th grade students participated individually in tutorial interviews centered on a problem-solving activity designed for learning basic algebra mechanics through diagrammatic modeling of an engaging narrative about a buccaneering giant burying and unearthing her treasure on a desert island. Participants were randomly assigned to…

  1. Comparison between project-based learning and discovery learning toward students' metacognitive strategies on global warming concept

    Science.gov (United States)

    Tumewu, Widya Anjelia; Wulan, Ana Ratna; Sanjaya, Yayan

    2017-05-01

    The purpose of this study was to know comparing the effectiveness of learning using Project-based learning (PjBL) and Discovery Learning (DL) toward students metacognitive strategies on global warming concept. A quasi-experimental research design with a The Matching-Only Pretest-Posttest Control Group Design was used in this study. The subjects were students of two classes 7th grade of one of junior high school in Bandung City, West Java of 2015/2016 academic year. The study was conducted on two experimental class, that were project-based learning treatment on the experimental class I and discovery learning treatment was done on the experimental class II. The data was collected through questionnaire to know students metacognitive strategies. The statistical analysis showed that there were statistically significant differences in students metacognitive strategies between project-based learning and discovery learning.

  2. A Study on Developing Learning Strategies in Violin Education

    Science.gov (United States)

    Afacan, Senol; Cilden, Seyda

    2018-01-01

    This study was conducted for the purpose of developing a valid and reliable learning strategies scale for students receiving violin education in Departments of Music at Fine Arts High Schools. The scale was applied to 391 violin students receiving education in the 11th and 12th grades in Departments of Music at Fine Arts High Schools in the…

  3. International Exchanges as a Learning Tool

    DEFF Research Database (Denmark)

    Austring, Bennye Düranc; Schlüntz, Ditte Annette

    The project focused on the learning outcome of three one-week camps in Latvia, Denmark and Poland, where about 40 8th grade students each place were working with art based activities like dance, song writing, DJ'ing and circus. Especially these six objectives were measured on: Foreign language sp...... speaking, Knowledge about other countries, Understanding od democracy and human rights, Personal development, Art-based learning benefits and Inclusion and motivation of young people. The positive development of 'knowledge of other countries' was the most eye-catching learning outcome....

  4. Foreword: The 12th International Conference on Vibrations at Surfaces (VAS 12) (Erice, 20 26 July 2007)

    Science.gov (United States)

    Benedek, Giorgio; Vattuone, Luca

    2008-06-01

    The 12th International Conference on Vibrations at Surfaces (VAS 12) took place from 20 26 July 2007 as an event of the International School of Solid State Physics at the Ettore Majorana Foundation and Centre for Scientific Culture, Erice (Italy). The format and special environment of the conference have contributed to its transition from a traditional, medium-size conference into a more effective workshop, with a series of lectures reporting the most recent developments in the field, two poster sessions presenting recent results and even works in progress being discussed. The papers collected in this issue cover the highlights of the conference very thoroughly. Quite a few novel aspects concerning vibrations at surfaces are represented here, for example: new aspects in surface phonon spectroscopy, such as the very recent progress in inelastic x-ray scattering, the first observation of the boson peak in disordered surfaces, progress in the theory of atom scattering inelastic resonances, the action spectroscopy, the study of polycrystalline surfaces with electron energy-loss spectroscopy etc; parallel developments in experimental vibrational studies of adsorbed phases, either inorganic or organic, with those in ab initio theoretical simulations; the theory of enhanced electron--phonon interaction in low dimensions (2D and 1D); the extension from the traditional realm of surface vibrations and spectroscopy to other aspects of surface dynamics, like friction and various nonlinear effects, and to relevant dynamical phenomena occurring at interfaces. Other novelties presented at the conference, but already published in recent issues of the Journal of Physics: Condensed Matter, are also worth mentioning: the spin-echo spectroscopy with 3He allowing for slow-dynamics spectroscopy at very high, unprecedented resolutions (2007 J. Phys.: Cond. Matter 19 300301 and 305010; the first demonstration of dissociative surface trapping of molecules (2007 J. Phys.: Cond. Matter 19

  5. Relics of continental lithosphere in the atlantic by data of (Th/U)th, (Th/U)pb, and K/Ti systematics

    International Nuclear Information System (INIS)

    Titayeva, N.A.; Mironov, Y.

    1996-01-01

    The problem of mantle heterogeneity of the Atlantic Ocean has been investigated. Th/U ratio is a sensitive geochemical tracer. This ratio can be calculated from 232Th/230Th or from 208Pb/206Pb since 230Th and 206Pb are decay product of 238U and 208Pb is a product of 232Th decay. The former way to get Th/U ratio is valid for quaternary volcanic rocks because of the relatively short 230Th half life (80000 years), the latter way gives an integral quantity characterizing the pre-oceanic history beginning from the onset of earth formation and ending about 150 million years ago. Clear distinctions between ''depleted oceanic'' and ''enriched continental'' reservoirs have been drawn from comparative analysis of rocks. (A.C.)

  6. X-ray spectral study of the Th6p,5f electron states in ThO2 and ThF4

    International Nuclear Information System (INIS)

    Teterin, Y.A.; Nikitin, A.S.; Teterin, A.Y.; Ivanov, K.E.; Utkin, I.O.; Nerehov, V.A.; Ryzhkov, M.V.; Vukchevich, I.J.

    2002-01-01

    The study of the Th6p,5f electron states in Th, ThO 2 and ThF was carried out on the basis of the X-ray photoelectron fine spectral structure parameters in the binding energy range of 0-∼ 1000 eV, X-ray O 4,5 (Th) emission spectra of the shallow (0-∼50 eV) electrons and results of theoretical calculations. As a result, despite the absence of the Th5f electrons in thorium atoms, the Th5f atomic orbitals were established to participate in the formation of molecular orbitals in thorium dioxide and tetrafluoride. In the MO LCAO approximation this allowed to suggest the possible existence of filled Th5f electronic states in thorium compounds. On the basis of the X-ray O 4,5 (Th) emission spectral structure parameters the effective formation of the inner valence molecular orbitals in the studied compounds was confirmed. (authors)

  7. The potential of 230Th for detection of ocean acidification impacts on pelagic carbonate production

    Directory of Open Access Journals (Sweden)

    C. Heinze

    2018-06-01

    Full Text Available Concentrations of dissolved 230Th in the ocean water column increase with depth due to scavenging and downward particle flux. Due to the 230Th scavenging process, any change in the calcium carbonate (CaCO3 fraction of the marine particle flux due to changes in biological CaCO3 hard-shell production as a consequence of progressing ocean acidification would be reflected in the dissolved 230Th activity. Our prognostic simulations with a biogeochemical ocean general circulation model using different scenarios for the reduction of CaCO3 production under ocean acidification and different greenhouse gas emission scenarios – the Representative Concentration Pathways (RCPs 8.5 to 2.6 – reveal the potential for deep 230Th measurements to detect reduced CaCO3 production at the sea surface. The time of emergence of an acidification-induced signal on dissolved 230Th is of the same order of magnitude as for alkalinity measurements. Interannual and decadal variability in factors other than a reduction in CaCO3 hard-shell production may mask the ocean-acidification-induced signal in dissolved 230Th and make detection of the pure CaCO3-induced signal more difficult so that only really strong changes in marine CaCO3 export would be unambiguously identifiable soon. Nevertheless, the impacts of changes in CaCO3 export production on marine 230Th are stronger than those for changes in POC (particulate organic carbon or clay fluxes.

  8. Interactive Multimodal Molecular Set – Designing Ludic Engaging Science Learning Content

    DEFF Research Database (Denmark)

    Thorsen, Tine Pinholt; Christiansen, Kasper Holm Bonde; Jakobsen Sillesen, Kristian

    2014-01-01

    This paper reports on an exploratory study investigating 10 primary school students’ interaction with an interactive multimodal molecular set fostering ludic engaging science learning content in primary schools (8th and 9th grade). The concept of the prototype design was to bridge the physical...... and virtual worlds with electronic tags and, through this, blend the familiarity of the computer and toys, to create a tool that provided a ludic approach to learning about atoms and molecules. The study was inspired by the participatory design and informant design methodologies and included design...

  9. Modelling self-efficacy, self-regulation, self-directed learning and career processes of adult professionals and relations with learning outcomes and labour market success

    NARCIS (Netherlands)

    Bijker, Monique; Van der Klink, Marcel; Boshuizen, Els

    2010-01-01

    Bijker, M. M., Van der Klink, M. R., & Boshuizen, H. P. A. (2010, 25-27 August). Modelling self-efficacy, self-regulation, self-directed learning and career processes of adult professionals and relations with learning outcomes and labour market success. Paper presented at the 5th EARLI-SIG14

  10. Potential pathogenetic role of Th17, Th0, and Th2 cells in erosive and reticular oral lichen planus.

    Science.gov (United States)

    Piccinni, M-P; Lombardelli, L; Logiodice, F; Tesi, D; Kullolli, O; Biagiotti, R; Giudizi, Mg; Romagnani, S; Maggi, E; Ficarra, G

    2014-03-01

    The role of Th17 cells and associated cytokines was investigated in oral lichen planus. 14 consecutive patients with oral lichen planus were investigated. For biological studies, tissues were taken from reticular or erosive lesions and from normal oral mucosa (controls) of the same patient. mRNA expression for IL-17F, IL-17A, MCP-1, IL-13, IL-2, IL-10, IL-1β, RANTES, IL-4, IL-12B, IL-8, IFN-γ, TNF-α, IL-1α, IL-18, TGF-β1, IL-23R, IL-7, IL-15, IL-6, MIG, IP-10, LTB, VEGF, IL-5, IL-27, IL-23A, GAPDH, PPIB, Foxp3, GATA3, and RORC was measured using the QuantiGene 2.0. Results showed that Th17-type and Th0-type molecules' mRNAs, when compared with results obtained from tissue controls, were increased in biopsies of erosive lesions, whereas Th2-type molecules' mRNAs were increased in reticular lesions. When the CD4+ T-cell clones, derived from oral lichen planus tissues and tissue controls, were analyzed, a higher prevalence of Th17 (confirmed by an increased CD161 expression) and Th0 CD4+ T clones was found in erosive lesions, whereas a prevalence of Th2 clones was observed in reticular lesions. Our data suggest that Th17, Th0, and Th2 cells, respectively, may have a role in the pathogenesis of erosive and reticular oral lichen planus. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. Comparisons between students' learning achievements of their conventional instruction and the science, technology and social conceptual instructional design on digestion system issue of secondary students at the 10th grade level

    Science.gov (United States)

    Wichalek, Supattra; Chayaburakul, Kanokporn; Santiboon, Toansakul

    2018-01-01

    The purposes of this action research study were 1) to develop learning activities according to the instructional designing model of science, technology, and social (STS) on Digestion Issue, 2) to compare students' learning achievements between their learning activities with the conventional instructional (CIM) and conceptual instructional designing methods of science, technology, and social (STS) on digestion system of secondary students at the 10th grade level with a sample size of 35 experimental student group of their STS learning method, and 91 controlling group in two classes in the first semester in academic year 2016. Using the 4-Instructional Innovative Lesson Plans, the Students' Learning Behaviour Observing Form, the Questionnaire on Teacher Behaviour Interaction (QTBI), the Researcher's Recording Form, the Learning Activity Form, and the Parallel Learning Achievement Test (LAT) were assessed. The results of this research have found that; the Index of Item Objective Congruence (IOC) value ranged from 0.67 to 1.00; the difficulty values were 0.47 and 0.79 for the CIM and STS methods, respectively, the discriminative validity for the LAT was ranged from 0.20 to 0.75. The reliability of the QTBI was 0.79. Students' responses of their learning achievements with the average means scores indicted of the normalized gain values of 0.79 for the STS group, and 0.50 and 0.36 for the CIM groups, respectively. Students' learning achievements of their post-test indicated that of a higher than pre-test, the pre-test and post-test assessments were also differentiated evidence at the 0.05 levels for the STS and CIM groups, significantly. The 22-students' learning outcomes from the STS group evidences at a high level, only of the 9-students' responses in a moderate level were developed of their learning achievements, responsibility.

  12. TNF-α inhibitors reduce the pathological Th1 -Th17 /Th2 imbalance in cutaneous mesenchymal stem cells of psoriasis patients.

    Science.gov (United States)

    Campanati, Anna; Orciani, Monia; Lazzarini, Raffaella; Ganzetti, Giulia; Consales, Veronica; Sorgentoni, Giulia; Di Primio, Roberto; Offidani, Annamaria

    2017-04-01

    Psoriasis is a disease characterized by an imbalance between Th 1 and Th 17 and Th 2 inflammatory axes, in which cutaneous mesenchymal stem cells (MSCs) are early involved, as they show a greater relative expression of several genes encoding for Th 1 and Th 17 cytokines. Therapeutic implications of TNF-α inhibitors on differentiated skin cells have been largely described in psoriasis; however, their effects on MSCs derived from patients with psoriasis have been only partially described. The aim of this work was to evaluate the effect of TNF-α inhibitors on cytokine milieu expressed by MSCs isolated from the skin of patients with psoriasis. Resident MSCs from skin of patients with psoriasis and healthy subjects have been isolated, characterized and profiled by PCR and ELISA for the expression of 22 cytokines involved in Th 1 , Th 2 and Th 17 pathways, both before and after 12 weeks therapy with TNF-α inhibitors. The administration of TNF-α inhibitors for 12-weeks acts on MSCs as follows: it reduces the expression of several Th 1 -Th 17 cytokines whose levels are elevated at baseline (IL-6, IL-8, IL-12, IL-23A, IFN-γ, TNF-α, CCL2, CCL20, CXCL2, CXCL5, IL-17A, IL-17C, IL-17F, IL-21, G-CSF). Similarly, it enhances the expression of several Th 2 cytokines which are underexpressed at baseline (IL-2, IL-4, IL-5), reducing the expression of those overexpressed at baseline (TGF-β and IL-13). TNF-α inhibitors could contribute to reduce the pathological imbalance between the Th 1 -Th 17 vs Th 2 axis in MSCs of patients with psoriasis. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Effect of practical training on the learning motivation profile of Japanese pharmacy students using structural equation modeling.

    Science.gov (United States)

    Yamamura, Shigeo; Takehira, Rieko

    2017-01-01

    To establish a model of Japanese pharmacy students' learning motivation profile and investigate the effects of pharmaceutical practical training programs on their learning motivation. The Science Motivation Questionnaire II was administered to pharmacy students in their 4th (before practical training), 5th (before practical training at clinical sites), and 6th (after all practical training) years of study at Josai International University in April, 2016. Factor analysis and multiple-group structural equation modeling were conducted for data analysis. A total of 165 students participated. The learning motivation profile was modeled with 4 factors (intrinsic, career, self-determination, and grade motivation), and the most effective learning motivation was grade motivation. In the multiple-group analysis, the fit of the model with the data was acceptable, and the estimated mean value of the factor of 'self-determination' in the learning motivation profile increased after the practical training programs (P= 0.048, Cohen's d = 0.43). Practical training programs in a 6-year course were effective for increasing learning motivation, based on 'self-determination' among Japanese pharmacy students. The results suggest that practical training programs are meaningful not only for providing clinical experience but also for raising learning motivation.

  14. PENGGUNAAN MODEL PROBLEM BASED LEARNING BERBANTUAN E-LEARNING TERHADAP KEMANDIRIAN BELAJAR MAHASISWA

    Directory of Open Access Journals (Sweden)

    Jusep Saputra

    2017-11-01

    Full Text Available Self-regulated learning of learners can be achieved, if in the process of learning mathematics provides an open opportunity for students to learn independently. This research is a mixed method type embedded design, which aims to do studies focused on the use of the Problem Based Learning (PBL model assisted e-learning to student self-regulated learning. Sample selection is done on the purposive sampling and was taken 2 class contracting courses of school math III. Class A numbered 50 members, 24 the superior group and 26 the low group, given the treatment with PBL models assisted e-learning and class B numbered 50, 27 the superior group and 23 the low group, with expository. Instruments used in this research is self-regulated learning questionnaire with Likert scale. Based on data analysis we concluded that (1 Self-regulated learning of superior and low student who obtains aided PBL models assisted e-learning is better than self-regulated learning of superior and low superior students who obtain expository.

  15. Indicators for successful learning in air traffic control training

    NARCIS (Netherlands)

    Van Meeuwen, Ludo; Brand-Gruwel, Saskia; Van Merriënboer, Jeroen; De Bock, Jeano; Kirschner, Paul A.

    2011-01-01

    Van Meeuwen, L. W., Brand-Gruwel, S., Van Merriënboer, J. J. G., De Bock, J. J. P. R., & Kirschner, P. A. (2010, August). Indicators for successful learning in air traffic control training. Paper presented at the 5th EARLI SIG 14 Learning and Professional Development Conference. Munich, Germany.

  16. A Game for Learning History on Mobile Devices

    Science.gov (United States)

    Cruz, Sónia; Carvalho, Ana Amélia A.; Araújo, Inês

    2017-01-01

    This paper presents a game designed to support teaching and learning of Portuguese History to 6th grade students. Firstly, a state of the art of mobile game-based learning for History is presented. Then we describe shortly the research carried out which aimed at the analysis of the games most played by students, followed by the identification of…

  17. Impairment of the Intrinsic Capability of Th1 Polarization in Irradiated Mice: A Close Look at the Imbalanced Th1/Th2 Response after Irradiation.

    Science.gov (United States)

    Chen, Renxiang; Wang, Yi-Wen; Fornace, Albert J; Li, Heng-Hong

    2016-12-01

    Two major CD4 + T-helper (Th) lineages are Th1 and Th2, and well balanced Th1/Th2 responses are essential for immune function. In previously published studies, it was reported that radiation induces a Th1/Th2 immune imbalance toward a Th2-dominant direction, and this imbalance may contribute to postirradiation immune dysfunction. The polarization of Th cells is driven by the cytokine milieu and controlled by intracellular regulatory pathways that respond to cytokine signaling. It is widely accepted that radiation induces cytokine aberration, however, the precise alterations of cytokines in various tissue environments have been difficult to evaluate. In addition, the effects of radiation on the intrinsic functions of Th cells remain uncharacterized. Therefore, how radiation affects Th1/Th2 balance remains somewhat unclear. To address this, we investigated the changes in the polarization capability of Th cells by isolating them from mice previously exposed to radiation and assessing the cells in an established in vitro Th polarization system. Our novel results demonstrate that prior exposure to radiation led to the persistent aberration of the inherent capability of Th cells to differentiate into Th1 and Th2 lineages. The parallel changes in expression of Th1-specific master transcription factors and the key genes in metabolic reprograming indicated that radiation affects the core components in Th1 polarization. While Th1 differentiation was impaired after irradiation, little adverse effect was observed in Th2 differentiation; both of these findings contribute to the known phenotypes of Th1/Th2 imbalance caused by radiation.

  18. Effectiveness of Web Quest in Enhancing 4th Grade Students' Spiritual Intelligence

    Science.gov (United States)

    Jwaifell, Mustafa; Al-Mouhtadi, Reham; Aldarabah, Intisar

    2015-01-01

    Spiritual intelligence has gained great interest from a good number of the researchers and scholars, while there is a lack of using new technologies such as WebQuest as an instructional tool; which is one of the e-learning applications in education in enhancing spiritual intelligence of 4th graders in Jordanian schools. This study aimed at…

  19. Role of Th1 and Th2 cells in autoimmune demyelinating disease

    NARCIS (Netherlands)

    Nagelkerken, L.

    1998-01-01

    Evidence is accumulating that Th1 cells play an important role in the development of multiple sclerosis (MS) and experimental allergic encephalomyelitis (EAE), whereas Th2 cells contribute to recovery from disease. A maj or determinant in the development of Th1 and Th2 cells is the type of

  20. 16th UK Workshop on Computational Intelligence

    CERN Document Server

    Gegov, Alexander; Jayne, Chrisina; Shen, Qiang

    2017-01-01

    The book is a timely report on advanced methods and applications of computational intelligence systems. It covers a long list of interconnected research areas, such as fuzzy systems, neural networks, evolutionary computation, evolving systems and machine learning. The individual chapters are based on peer-reviewed contributions presented at the 16th Annual UK Workshop on Computational Intelligence, held on September 7-9, 2016, in Lancaster, UK. The book puts a special emphasis on novels methods and reports on their use in a wide range of applications areas, thus providing both academics and professionals with a comprehensive and timely overview of new trends in computational intelligence.

  1. Chilean 12th graders’ Attitudes towards English as a Foreign Language

    Directory of Open Access Journals (Sweden)

    Eric Gómez Burgos

    2015-10-01

    Full Text Available This article aims to provide the results of a research focusing on 12th graders’ attitudes towards English as a Foreign Language in two secondary schools in Puerto Montt, Chile. Attitude towards a language has been considered as an important factor that influences the process of learning a foreign language (Shams, 2008; for this reason, it is fundamental to identify students’ attitudes since positive attitudes towards English allow the students to have favourable orientation towards learning it (Karahan, 2007. Under this premise, this study corresponds to a case study that includes a quantitative method of data analysis. A survey of five dimensions was conducted amongst 154 students in order to measure their attitudes towards the target language. The results show that their attitudes towards English as a foreign language are favourable; however, the dimensions related to learning English, and English as a subject at school obtained unfavourable attitudes.

  2. 5th International Conference on Mathematical Modeling in Physical Sciences (IC-MSquare 2016)

    International Nuclear Information System (INIS)

    Vagenas, Elias C.; Vlachos, Dimitrios S.

    2016-01-01

    The 5th International Conference on Mathematical Modeling in Physical Sciences (IC- MSQUARE) took place at Athens, Greece, from Monday, 23"t"h of May, to Thursday, 26"t"h of May 2016. The Conference was attended by more than 130 participants and hosted about 170 oral, poster, and virtual presentations while counted more than 500 pre-registered authors. The 5"t"h IC-MSQUARE consisted of different and diverging workshops and thus covered various research fields where Mathematical Modeling is used, such as Theoretical/Mathematical Physics, Neutrino Physics, Non-Integrable Systems, Dynamical Systems, Computational Nanoscience, Biological Physics, Computational Biomechanics, Complex Networks, Stochastic Modeling, Fractional Statistics, DNA Dynamics, Macroeconomics etc. The scientific program was rather heavy since after the Keynote and Invited Talks in the morning, three parallel oral and one poster session were running every day. However, according to all attendees, the program was excellent with high level talks and the scientific environment was fruitful, thus all attendees had a creative time. We would like to thank the Keynote Speaker and the Invited Speakers for their significant contribution to IC-MSQUARE. We also would like to thank the Members of the International Advisory and Scientific Committees as well as the Members of the Organizing Committee. (paper)

  3. Report of the 13th IEA workshop on radiation effects in ceramic insulators

    International Nuclear Information System (INIS)

    2004-03-01

    The 13th IEA Workshop on Radiation Effects in Ceramic Insulators, based on Annex II: Experimentation on Radiation Damage in Fusion Materials, to the IEA Implementing Agreement for a Programme of Research and Development on Radiation Damage in Fusion Materials, was held on the 9th, December, 2003, at Kyoto International Conference Center, in Kyoto, Japan, in conjunction with the 11th International Conference on Fusion Reactor Materials (ICFRM-11). 44 participants from 10 countries (26 from Japan, 5 from Spain, 3 from Belgium, 3 from USA, 2 from RF, each 1 from Austria, Greece, Italy, Romania, and UK) gathered together and discussed following issues extensively, with the newest experimental results, after the welcome remarks by one of the organizer and chairpersons, Dr. E.R. Hodgson of CIEMAT. Effects of electric field on radiation induced microstructural evolution, parasitic electrical current and voltage induced in cables and wires by radiation effects, optical materials, IFMIF related issues and fundamental aspects were discussed. Significant results such as an observation of γ-alumina and aluminum colloid formation for the Radiation Induced Electrical Degradation mechanism are obtained. This report is workshop summary, abstracts and documents of the 13th IEA Workshop on Radiation Effects in Ceramic Insulators. (author)

  4. The Balance of Th1/Th2 and LAP+Tregs/Th17 Cells Is Crucial for Graft Survival in Allogeneic Corneal Transplantation

    Directory of Open Access Journals (Sweden)

    Shang Li

    2018-01-01

    Full Text Available Purpose. CD4+LAP+ T cells are newly discovered regulatory T cells (Tregs. The aim of this study is to investigate the balance of Th1/Th2 and LAP+Tregs/Th17 in mice after allogeneic corneal transplantation. Methods. A total of 65 mice received orthotopic penetrating transplantation. According to the survival scores of the grafts, the mice were divided into the rejection group and the survival group 3 weeks after transplantation. Th1, Th2, Th17, and regulatory T cells in the ipsilateral drainage lymph nodes and spleens were measured with flow cytometry. The related cytokines in aqueous humor were also analyzed. Results. The frequencies of Foxp3+Tregs, GARP+Tregs, and LAP+Tregs in the survival group were significantly higher than those in the rejection group. And the expression trend of CD4+LAP+ T cells and CD4+GARP+ T cells was consistent. The level of IFN-γ, TNF, IL-6, and IL-17A markedly increased in aqueous humor during corneal allograft rejection. The ratio of Th1/Th2 and Th17/LAP+Tregs significantly increased in the rejection group at the 3rd week after corneal transplantation. Conclusion. LAP+Tregs might be regarded as substitute for Foxp3+Tregs. The balance of Th1/Th2 and LAP+Tregs/Th17 is crucial for corneal allograft survival.

  5. spv locus aggravates Salmonella infection of zebrafish adult by inducing Th1/Th2 shift to Th2 polarization.

    Science.gov (United States)

    Wu, Shu-Yan; Wang, Li-Dan; Xu, Guang-Mei; Yang, Si-di; Deng, Qi-Feng; Li, Yuan-Yuan; Huang, Rui

    2017-08-01

    Salmonella enterica serovar typhimurium (S. typhimurium) are facultative intracellular enteric pathogens causing disease with a broad range of hosts. It was known that Th1-type cytokines such as IFN-γ, IL-12, and TNF-α etc. could induce protective immunity against intracellular pathogens, while Th2-type cytokines such as IL-4, IL-10, and IL-13 etc. are proved to help pathogens survive inside hosts and cause severe infection. One of the critical virulence factor attributes to the pathogenesis of S. typhimurium is Salmonella plasmid virulence genes (spv). Until now, the interaction between spv locus and the predictable generation of Th1 or Th2 immune responses to Salmonella has not been identified. In this study, zebrafish adults were employed to explore the effect of spv locus on Salmonella pathogenesis as well as host adaptive immune responses especially shift of Th1/Th2 balance. The pathological changes of intestines and livers in zebrafish were observed by hematoxylin-eosin (HE) staining and electron microscopy. Levels of the transcription factors of Th1 (Tbx21) and Th2 (GATA3) were measured by real-time quantitative PCR (RT-qPCR). Expression of cytokines were determined by using RT-qPCR and ELISA, respectively. Results showed that spv operon aggravates damage of zebrafish. Furthermore, it demonstrated that spv locus could inhibit the transcription of tbx21 gene and suppress the expression of cytokines IFN-γ, IL-12 and TNF-α. On the contrary, the transcription of gata3 gene could be promoted and the expression of cytokines IL-4, IL-10 and IL-13 were enhanced by spv locus. Taken together, our data revealed that spv locus could aggravate Salmonella infection of zebrafish adult by inducing an imbalance of Th1/Th2 immune response and resulting in a detrimental Th2 bias of host. Copyright © 2017. Published by Elsevier Ltd.

  6. 60th anniversary celebrations: events in the coming 10 days

    CERN Multimedia

    2014-01-01

    This is an eventful week. Read this summary and don’t miss these unique events!   Saturday 20 September: Particle Fever film screening and Comedy Night show: the event is sold out but the discussion that will take place between 8.45 p.m. and 9.30 p.m. will be available on webcast. Thursday 25 and Friday 26 September: Researchers' Night - POPscience. To make the Researchers' Night even more POPular, CERN will meet its public outside the Laboratory: at FNAC Rive, the Salle Centrale Madeleine (free entrance, reservation possible), and the Théâtre du Bordeau in Saint-Genis-Pouilly. A unique mix of arts, poetry, theatre, music, science and encounters. Friday 26 September: From Physics to daily life colloquium in the Main Auditorium will feature talks by several scientists and experts of the technologies that have changed our life. The webcast in English and French will be available from 9 a.m. Monday 29 ...

  7. 18th International Laser Radar Conference

    CERN Document Server

    Neuber, Roland; Rairoux, Patrick; Wandinger, Ulla

    1997-01-01

    Lidar or laser radar, the depth-resolved remote measurement of atmospheric parameters with optical means, has become an important tool in the field of atmospheric and environmental remote sensing. In this volume the latest progress in the development of lidar methods, experiments, and applications is described. The content is based on selected and thoroughly refereed papers presented at the 18th International Laser Radar Conference, Berlin, 22-26 July 1996. The book is divided into six parts which cover the topics of tropospheric aerosols and clouds, lidar in space, wind, water vapor, troposheric trace gases and plumes, and stratospheric and mesospheric profiling. As a supplement to fundamental lidar textbooks this volume may serve as a guide for scientists, engineers, and graduate students through the blossoming field of modern lidar techniques and their contribution to atmospheric and environmental research.

  8. Preface to Special Topic: Selected Papers from the 5th International Conference on Optofluidics

    OpenAIRE

    Fan, Shih-Kang; Yang, Zhenchuan

    2016-01-01

    The 5th International Conference on Optofluidics (Optofluidics 2015) was held in Taipei, Taiwan, July 26–29, 2015. The aim of this conference was to provide a forum to promote scientific exchange and to foster closer networks and collaborative ties between leading international researchers in optics and micro/nanofluidics across various disciplines. The scope of Optofluidics 2015 was deliberately broad and interdisciplinary, encompassing the latest advances and the most innovat...

  9. Let's Face(book) It: Analyzing Interactions in Social Network Groups for Chemistry Learning

    Science.gov (United States)

    Rap, Shelley; Blonder, Ron

    2016-02-01

    We examined how social network (SN) groups contribute to the learning of chemistry. The main goal was to determine whether chemistry learning could occur in the group discourse. The emphasis was on groups of students in the 11th and 12th grades who learn chemistry in preparation for their final external examination. A total of 1118 discourse events were tallied in the different groups. We analyzed the different events that were found in chemistry learning Facebook groups (CLFGs). The analysis revealed that seven types of interactions were observed in the CLFGs: The most common interaction (47 %) dealt with organizing learning (e.g., announcements regarding homework, the location of the next class); learning interactions were observed in 22 % of the posts, and links to learning materials and social interactions constituted about 20 % each. The learning events that were ascertained underwent a deeper examination and three different types of chemistry learning interactions were identified. This examination was based on the theoretical framework of the commognitive approach to learning (Sfard in Thinking as communicating. Cambridge University Press, Cambridge, 2008), which will be explained. The identified learning interactions that were observed in the Facebook groups illustrate the potential of SNs to serve as an additional tool for teachers to advance their students' learning of chemistry.

  10. Thermal expansion studies on Th(MoO4)2, Na2Th(MoO4)3 and Na4Th(MoO4)4

    International Nuclear Information System (INIS)

    Keskar, Meera; Krishnan, K.; Dahale, N.D.

    2008-01-01

    Thermal expansion behavior of Th(MoO 4 ) 2 , Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 was studied under vacuum in the temperature range of 298-1123 K by high temperature X-ray diffractometer. Th(MoO 4 ) 2 was synthesized by reacting ThO 2 with 2 mol of MoO 3 , at 1073 K in air and Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 were prepared by reacting Th(MoO 4 ) 2 with 1 and 2 mol of Na 2 MoO 4 , respectively at 873 K in air. The XRD data of Th(MoO 4 ) 2 was indexed on orthorhombic system where as XRD data of Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 were indexed on tetragonal system. The lattice parameters and cell volume of all the three compounds, fit into polynomial expression with respect to temperature, showed positive thermal expansion (PTE) up to 1123 K. The average value of thermal expansion coefficients for Th(MoO 4 ) 2 , Na 2 Th(MoO 4 ) 3 and Na 4 Th(MoO 4 ) 4 were determined from the high temperature data

  11. Studies on Th(IV) and Zr(IV) complexes of oxygen donor ligands

    International Nuclear Information System (INIS)

    Agarwal, R.K.; Srivastava, M.; Srivastava, A.K.

    1981-01-01

    In recent years a large number of complexes of amine N-oxides with a wide variety of metal salts have been isolated and characterized. Less attention has been paid to the aromatic amine N-oxides complexes with Th(IV) thiocyanate. In the present communication studies are reported on Th(IV) thiocyanate complexes of pyridine N-oxide (PyO), quinoline N-oxide (QO), isoquinoline N-oxide (IsqO), 2-picoline N-oxide (2-picO), 3-picoline N-oxide (3-picO) and 4-picoline N-oxide (4-picO) and comparisons are made with the existing complexes of 2,6-lutidine N-oxide (LNO), 2, 2'bipyridine N-N'-dioxide (BipyO 2 ), mono N-oxides of 2,2'-bipyridine (BipyNO) and 1,10-phenanthroline (PhenNO) and 1, 10-phenanthroline N-N'-dioxide (PhenO 2 ). The analytical data correspond to the composition Th(NCS) 4 .4L. The molar conductance of all the complexes in nitrobenzene in the range 2.5 to 4.5 Ω -1 cm 2 mol -1 indicate them to be non-electrolytes. The results of IR spectroscopy and thermogravimetry are given and discussed. (author)

  12. Computer assisted instruction on "learning nutrition flags for deaf 5th grade and 6th grad students": effectiveness of instruction.

    Science.gov (United States)

    Srisorachatr, Suwat; Huadong, Yotsinee; Hudthagosol, Chatrapa; Danthanavanich, Suksiri

    2013-12-01

    Deaf students are of a number of under privilege group for whom there are limited resources for their use, related to health including nutrition. The purpose of this research was to create computer-assisted instruction for "nutrition flags" for 5 and 6th grade students. The content of nutrition included the concept of a healthy balance diets and portion sizes of each food group. The content and pictures for computer-assisted instruction came from existing curriculum, and focused on nutritional content. The contents in this instruction were divided into three units according to students' learning capacity. The story boards were developed by staff including nutritionists, Thai sign language interpreters, and deaf students. Then, the contents and nutrition vocabulary were translated into Thai sign language. After recording the sign language on video, this material was merged with the contents and converted into a computer program. The computer assisted instruction was tested with students from Nakon Pathom School for the Deaf The first trial was conducted with three students, the second with five students, and the third with 15 students during the academic year 2009. The computer- assisted instruction was revised until it met the standard criteria of 80/80. Effectiveness testing was carried out with 36 students for five consecutive days. On the first day, the pre-test was completed, and on days 2-4, the students performed self-study and completed the exercises for units 1-3, with 50 minutes spent on each unit. The post-test was completed on the last day. The study was conducted during the 2010 academic year Data analysis was performed using the t-test. The results showed an effectiveness of 81.85/82.22, which was higher than the standard criteria of 80/80. The post-test average score was higher than the pre-test average score with a statistical significance level at p < 0.0001. Suggestions for instruction for the deaf are that the length of the instruction in each

  13. 6th Annual Homeland Security and Defense Education Summit, Developing an Adaptive Homeland Security Environment

    OpenAIRE

    2013-01-01

    6th Annual Homeland Security and Defense Education Summit Developing an Adaptive Homeland Security Environment, Burlington, MA, September 26-28, 2013 2013 Summit Agenda Naval Postgraduate School Center for Homeland Defense and Security In Partnership With Northeastern University, Department of Homeland Security, Federal Emergency Management Agency, National Guard Homeland Security Institute, National Homeland Defense Foundation Naval Postgraduate School Center for Homeland Defense and S...

  14. An assessment of student experiences and learning based on a novel undergraduate e-learning resource.

    Science.gov (United States)

    Mehta, S; Clarke, F; Fleming, P S

    2016-08-12

    Purpose/objectives The aims of this study were to describe the development of a novel e-learning resource and to assess its impact on student learning experiences and orthodontic knowledge.Methods Thirty-two 4th year dental undergraduate students at Queen Mary University of London were randomly allocated to receive electronic access to e-learning material covering various undergraduate orthodontic topics over a 6-week period. Thirty-one control students were not given access during the study period. All students were asked to complete electronic quizzes both before (T0) and after (T1) the study period and a general questionnaire concerning familiarity with e-learning. The test group also completed a user satisfaction questionnaire at T1. Two focus groups were also undertaken to explore learners' experiences and suggestions in relation to the resource.Results The mean quiz result improved by 3.9% and 4.5% in the control and test groups, respectively. An independent t-test, however, demonstrated a lack of statistical significance in knowledge gain between control and test groups (P = 0.941). The qualitative feedback indicated that students believed that use of the resource enhanced knowledge and basic understanding with students expressing a wish to ingrain similar resources in other areas of undergraduate teaching.Conclusions Use of the novel orthodontic e-resource by 4th year undergraduate students over a 6-week period did not result in a significant improvement in subject knowledge. However, the e-learning has proven popular among undergraduates and the resources will continue to be refined.

  15. 26Mg(p,n)26Al and 23Na(α,n)26Al reactions

    International Nuclear Information System (INIS)

    Skelton, R.T.

    1985-01-01

    Cross sections for the 26 Mg(p,n) 26 Al reaction were measured from threshold at 4.988 MeV to 5.820 MeV. Cross sections for the 23 Na(α,n) 26 Al reaction were measured from threshold at 3.483 MeV to 4.597 MeV. In each case, separate measurements were to the ground state and to the first and second excited states of 26 Al. Cross sections for the inverse reactions were calculated and reaction rate factors relating to the destruction of 26 Al in a supernova environment were determined. Astrophysical implications relating to the observation of live and extinct 26 Al are discussed. Excitation functions for several additional exit channels for the 26 Mg + rho and 23 Na + α reactions are reported

  16. Academic stress-induced changes in Th1- and Th2-cytokine response

    Directory of Open Access Journals (Sweden)

    Areej M. Assaf

    2017-12-01

    Full Text Available Psychological stress stimulates physiological responses releasing catecholamines and corticoids, which act via corresponding receptors on immune cells, producing a shift in the cytokine balance. These responses are variable depending on the nature of stressors. The effect of the academic stress on the production of the Th1-cytokines (TNF-α, IFN-γ, IL-1β, IL-2, IL-6 and IL-8 and Th2-cytokines (IL-1ra, IL-4, IL-5 and IL-10 on 35 medical/health sciences students after completing their questionnaires was investigated. Blood samples were taken at three stages; baseline stage at the beginning, midterm and final academic examination stages. Plasma cortisol and cytokines were measured during the three stages. The last two stages were compared with the baseline non-stress period. Results of the stress induced during the final examination stage were the highest with a significant increase in cortisol release, IL-4, IL-5 and IL-1ra release with a shift in Th1:Th2 cytokines balance towards Th2. Whereby, the midterm stage did not show significant reduction in Th1-cytokines except for TNF-α, with an increase in IFN-γ level that was reduced in the third stage. Th2 cytokine, IL-1ra, had positive correlations with Th1 cytokines; IL-2 and IFN-γ in the second stage and IL-6 cytokine in the third stage. Cortisol was positively correlated with IL-8 in the last stage and heart rates had negative correlation with IL-10 in the first and last stages. Findings of this study indicate that exam stress down-regulates Th1 with a selective up-regulation of Th2-cytokines. In conclusion, Cortisol might have a role in suppressing the release of Th1- mediated cellular immune response which could increase the vulnerability among the students to infectious diseases.

  17. Academic stress-induced changes in Th1- and Th2-cytokine response.

    Science.gov (United States)

    Assaf, Areej M; Al-Abbassi, Reem; Al-Binni, Maysaa

    2017-12-01

    Psychological stress stimulates physiological responses releasing catecholamines and corticoids, which act via corresponding receptors on immune cells, producing a shift in the cytokine balance. These responses are variable depending on the nature of stressors. The effect of the academic stress on the production of the Th1-cytokines (TNF-α, IFN-γ, IL-1β, IL-2, IL-6 and IL-8) and Th2-cytokines (IL-1ra, IL-4, IL-5 and IL-10) on 35 medical/health sciences students after completing their questionnaires was investigated. Blood samples were taken at three stages; baseline stage at the beginning, midterm and final academic examination stages. Plasma cortisol and cytokines were measured during the three stages. The last two stages were compared with the baseline non-stress period. Results of the stress induced during the final examination stage were the highest with a significant increase in cortisol release, IL-4, IL-5 and IL-1ra release with a shift in Th1:Th2 cytokines balance towards Th2. Whereby, the midterm stage did not show significant reduction in Th1-cytokines except for TNF-α, with an increase in IFN-γ level that was reduced in the third stage. Th2 cytokine, IL-1ra, had positive correlations with Th1 cytokines; IL-2 and IFN-γ in the second stage and IL-6 cytokine in the third stage. Cortisol was positively correlated with IL-8 in the last stage and heart rates had negative correlation with IL-10 in the first and last stages. Findings of this study indicate that exam stress down-regulates Th1 with a selective up-regulation of Th2-cytokines. In conclusion, Cortisol might have a role in suppressing the release of Th1- mediated cellular immune response which could increase the vulnerability among the students to infectious diseases.

  18. Individual values, learning routines and academic procrastination.

    Science.gov (United States)

    Dietz, Franziska; Hofer, Manfred; Fries, Stefan

    2007-12-01

    Academic procrastination, the tendency to postpone learning activities, is regarded as a consequence of postmodern values that are prominent in post-industrialized societies. When students strive for leisure goals and have no structured routines for academic tasks, delaying strenuous learning activities becomes probable. The model tested in this study posits that postmodern value orientations are positively related to procrastination and to a lack of daily routines concerning the performance of academic activities. In contrast, modern values are negatively related to procrastination and positively to learning routines. Academic procrastination, in-turn, should be associated with the tendency to prefer leisure activities to schoolwork in case of conflicts between these two life domains. Seven hundred and four students from 6th and 8th grade with a mean age of 13.5 years participated in the study. The sample included students from all tracks of the German educational system. Students completed a questionnaire containing two value prototypes as well as scales on learning routines and procrastination. Decisions in motivational conflicts were measured using two vignettes. Results from structural equation modelling supported the proposed model for the whole sample as well as for each school track. A planned course of the day can prevent procrastination and foster decisions for academic tasks in case of conflicts. Students' learning takes place within a societal context and reflects the values held in the respective culture.

  19. 4th International conference on Knowledge Discovery and Data Mining

    CERN Document Server

    Knowledge Discovery and Data Mining

    2012-01-01

    The volume includes a set of selected papers extended and revised from the 4th International conference on Knowledge Discovery and Data Mining, March 1-2, 2011, Macau, Chin.   This Volume is to provide a forum for researchers, educators, engineers, and government officials involved in the general areas of knowledge discovery and data mining and learning to disseminate their latest research results and exchange views on the future research directions of these fields. 108 high-quality papers are included in the volume.

  20. Attending to Structural Programming Features Predicts Differences in Learning and Motivation

    Science.gov (United States)

    Witherspoon, Eben B.; Schunn, Christian D.; Higashi, Ross M.; Shoop, Robin

    2018-01-01

    Educational robotics programs offer an engaging opportunity to potentially teach core computer science concepts and practices in K-12 classrooms. Here, we test the effects of units with different programming content within a virtual robotics context on both learning gains and motivational changes in middle school (6th-8th grade) robotics…

  1. Asymmetrically deformed third minimum in the 231Th and 233Th fission barriers

    International Nuclear Information System (INIS)

    Blons, J.; Mazur, C.; Paya, D.; Ribrag, M.; Weigmann, H.

    1981-01-01

    Neutron induced fission cross-sections of 230 Th and 232 Th have been measured up to 5 MeV. The electron linear accelerator (GELINA) has been used as a neutron time of flight spectrometer with a nominal resolution of 84 psec/m for 230 Th(n,f) and 42 psec/m for 232 Th(n,f) reaction. The fission fragment detector was a 6 cell gas scintillator filled with xenon. The existence of fine structure peaks, a few keV wide, in both the 230 Th(n,f) and 232 Th(n,f) cross sections, is definitively confirmed. The analysis of the two vibrational resonances located respectively at 720 keV for 230 Th(the figure) and 1.6 MeV for 232 Th, shows clearly that these peaks can be interpreted, in terms of two rotational bands with opposite parities. This parity degeneracy is a consequence of the asymmetric, pear-like deformation of the excited nucleus [ru

  2. Proceedings of the 42nd basic science seminar. (The 7th workshop on neutron crystallography in biology)

    International Nuclear Information System (INIS)

    Niimura, Nobuo

    1996-02-01

    42nd advanced science seminar (the 7th workshop on neutron crystallography in biology) was held on October, 25-26, 1995 at Tokai. Forty three participants from university, research institute and private company took part in the workshop and there were 17 lectures given. The proceedings collect the figures and tables which the speakers used in their lectures. (author)

  3. Effect of practical training on the learning motivation profile of Japanese pharmacy students using structural equation modeling

    Directory of Open Access Journals (Sweden)

    Shigeo Yamamura

    2017-02-01

    Full Text Available Purpose To establish a model of Japanese pharmacy students’ learning motivation profile and investigate the effects of pharmaceutical practical training programs on their learning motivation. Methods The Science Motivation Questionnaire II was administered to pharmacy students in their 4th (before practical training, 5th (before practical training at clinical sites, and 6th (after all practical training years of study at Josai International University in April, 2016. Factor analysis and multiple-group structural equation modeling were conducted for data analysis. Results A total of 165 students participated. The learning motivation profile was modeled with 4 factors (intrinsic, career, self-determination, and grade motivation, and the most effective learning motivation was grade motivation. In the multiple-group analysis, the fit of the model with the data was acceptable, and the estimated mean value of the factor of ‘self-determination’ in the learning motivation profile increased after the practical training programs (P= 0.048, Cohen’s d= 0.43. Conclusion Practical training programs in a 6-year course were effective for increasing learning motivation, based on ‘self-determination’ among Japanese pharmacy students. The results suggest that practical training programs are meaningful not only for providing clinical experience but also for raising learning motivation.

  4. E-Learning: Its Implementation in Higher Institutions in Nigeria ...

    African Journals Online (AJOL)

    Advances in computer, communication and network technology have led to the evolution of new ways of learning generally grouped as, and termed e-learning. It is a name that came into existence not more than a decade ago though it was being implemented since the second half of the 20th century in its various sub forms.

  5. Integrating a WebQuest in the Primary School Curriculum Using Anchored Instruction: Effect on Learning Outcomes

    NARCIS (Netherlands)

    Segers, P.C.J.; Droop, W.; Verhoeven, L.T.W.

    2010-01-01

    Based on a literature review, a means for integrating WebQuests in day-to-day school activities is introduced using principles of Anchored Instruction. Following these ideas in an effect study, including 109 children in 4th, 5th and 6th grade, significant learning gains were found, with a large

  6. Boundary crossing and learning identities – digital storytelling in primary schools

    Directory of Open Access Journals (Sweden)

    Anne Mette Bjørgen

    2010-11-01

    Full Text Available This article contributes to academic discussions on how digital storytelling in an educational setting may have potential to build and develop learning identities, agency and digital competences. With a socio-cultural framework on learning and identity as a point of departure, the article sets out to study these issues approached as boundary crossing between the intersecting contexts of leisure time and school. The analysis draws on three examples of digital storytelling among 5th - 7th graders in three Norwegian primary school classes. My findings suggest that digital storytelling might represent a boundary crossing enabling pupils to adopt new roles as producers of creative content, as mentors or guides, to explore new technology and software in a context different from that of outside school and to learn and develop competences related to production processes and multimodal resources. I argue that digital storytelling has a potential to contribute to learning, learning identity and agency, provided it is based on a more fully developed pedagogical strategy of carefully linking school and leisure time.

  7. Circulating endothelial progenitor cells, Th1/Th2/Th17-related cytokines, and endothelial dysfunction in resistant hypertension.

    Science.gov (United States)

    Magen, Eli; Feldman, Arie; Cohen, Ziona; Alon, Dora Ben; Minz, Evegeny; Chernyavsky, Alexey; Linov, Lina; Mishal, Joseph; Schlezinger, Menacham; Sthoeger, Zev

    2010-02-01

    A possible link between chronic vascular inflammation and arterial hypertension is now an object of intensive studies. To compare Th1/Th2/Th17 cells-related cytokines, circulating endothelial progenitor cells (EPC), and endothelial function in subjects with resistant arterial hypertension (RAH) and controlled arterial hypertension (CAH). Blood pressure was measured by electronic sphygmomanometer. EPC were identified as CD34+/CD133+/kinase insert domain receptor (KDR)+ cells by flow cytometry. Th1/Th2/Th17 cells-related cytokines were identified using the Human Th1/Th2/Th17 Cytokines MultiAnalyte ELISArray Kit. Endothelium-dependent (FMD) vasodilatation of brachial artery was measured by Doppler ultrasound scanning. RAH group (n = 20) and CAH group (n = 20) and 17 healthy individuals (control group) were recruited. In the RAH group, lower blood levels of EPC number (42.4 +/- 16.7 cells/mL) and EPC% (0.19 +/- 0.08%) were observed than in the CAH group (93.1 +/- 88.7 cells/mL; P = 0.017; 0.27 +/- 0.17; P = 0.036) and control group (68.5 +/- 63.6 cells/mL; P < 0.001; 0.28 +/- 0.17%; P = 0.003), respectively. Plasma transforming growth factor-beta1 levels were significantly higher in the RAH group (1767 +/- 364 pg/mL) than in the CAH group (1292 +/- 349; P < 0.001) and in control group (1203 +/- 419 pg/mL; P < 0.001). In the RAH group, statistically significant negative correlation was observed between systolic blood pressure and EPC% (r = -0.72, P < 0.01). FMD in the RAH group was significantly lower (5.5 +/- 0.8%) than in the CAH group (9.2 +/- 1.4; P < 0.001) and in healthy controls (10.1 +/- 1.1%; P < 0.001). RAH is characterized by reduced circulating EPC, substantial endothelial dysfunction, and increased plasma transforming growth factor-beta1 levels.

  8. Inquiry learning for gender equity using History of Science in Life and Earth Sciences’ learning environments

    OpenAIRE

    C. Sousa

    2016-01-01

    [EN] The main objective of the present work is the selection and integration of objectives and methods of education for gender equity within the Life and Earth Sciences’ learning environments in the current portuguese frameworks of middle and high school. My proposal combines inquiry learning-teaching methods with the aim of promoting gender equity, mainly focusing in relevant 20th century women-scientists with a huge contribute to the History of Science.The hands-on and minds-on activities p...

  9. The Effects of Self-Paced Blended Learning of Mathematics

    Science.gov (United States)

    Balentyne, Phoebe; Varga, Mary Alice

    2016-01-01

    As online and blended learning gain more popularity in education, it becomes more important to understand their effects on student learning. The purpose of this study was to explore the effects of self-paced blended learning of mathematics on the attitudes and achievement of 26 high ability middle school students, and investigate the relationship…

  10. Oxidative stress modulates the cytokine response of differentiated Th17 and Th1 cells.

    Science.gov (United States)

    Abimannan, Thiruvaimozhi; Peroumal, Doureradjou; Parida, Jyoti R; Barik, Prakash K; Padhan, Prasanta; Devadas, Satish

    2016-10-01

    Reactive oxygen species (ROS) signaling is critical in T helper (Th) cell differentiation; however its role in differentiated Th cell functions is unclear. In this study, we investigated the role of oxidative stress on the effector functions of in vitro differentiated mouse Th17 and Th1 cells or CD4 + T cells from patients with Rheumatoid Arthritis using pro-oxidants plumbagin (PB) and hydrogen peroxide. We found that in mouse Th cells, non-toxic concentration of pro-oxidants inhibited reactivation induced expression of IL-17A in Th17 and IFN-γ in Th1 cells by reducing the expression of their respective TFs, RORγt and T-bet. Interestingly, in both the subsets, PB increased the expression of IL-4 by enhancing reactivation induced ERK1/2 phosphorylation. We further investigated the cytokine modulatory effect of PB on CD4 + T cells isolated from PBMCs of patients with Rheumatoid Arthritis, a well-known Th17 and or Th1 mediated disease. In human CD4 + T cells from Rheumatoid Arthritis patients, PB reduced the frequencies of IL-17A + (Th17), IFN - γ + (Th1) and IL-17A + /IFN - γ + (Th17/1) cells and also inhibited the production of pro-inflammatory cytokines TNF-α and IL-6. N-Acetyl Cysteine (NAC) an antioxidant completely reversed PB mediated cytokine modulatory effects in both mouse and human cells indicating a direct role for ROS. Together our data suggest that oxidative microenvironment can alter cytokine response of terminally differentiated cells and thus altering intracellular ROS could be a potential way to target Th17 and Th1 cells in autoimmune disorders. Copyright © 2016. Published by Elsevier Inc.

  11. Positioning Learning Design: Learner Experience and the challenges of transforming teaching practice

    NARCIS (Netherlands)

    Johnson, Mark; Griffiths, Dai; Hanslot, Zubair

    2010-01-01

    Johnson, M., Griffiths, D., & Hanslot, Z. (2010). Positioning Learning Design: Learner Experience and the challenges of transforming teaching practice. In D. Griffiths, & R. Koper (Eds.), Rethinking Learning and Employment at a Time of Economic Uncertainty. Proceedings of the 6th TENCompetence Open

  12. Facilitating Work Based Learning Projects: A Business Process Oriented Knowledge Management Approach

    NARCIS (Netherlands)

    Miao, Yongwu; Sloep, Peter; Koper, Rob

    2009-01-01

    Miao, Y., Sloep, P. B., & Koper, R. (2010). Facilitating Work Based Learning Projects: A Business Process Oriented Knowledge Management Approach. In D. Griffiths & R. Koper (Eds.), Rethinking Learning and Employment at a Time of Economic Uncertainty. Proceedings of the 6th TENCompetence Open

  13. A design-based approach with vocational teachers to promote self-regulated learning

    NARCIS (Netherlands)

    Jossberger, Helen; Brand-Gruwel, Saskia; Van de Wiel, Margje; Boshuizen, Els

    2011-01-01

    Jossberger, H., Brand-Gruwel, S., Van de Wiel, M., & Boshuizen, H. P. A. (2011, August). A design-based approach with vocational teachers to promote self-regulated learning. Presentation at the 14th European Conference for Research on Learning and Instruction (EARLI), Exeter, England.

  14. Anesthesiology teaching during undergraduation through an academic league: what is the impact in students' learning?

    Science.gov (United States)

    Ramalho, Alan Saito; Silva, Felipe Duarte; Kronemberger, Tatiana Barboza; Pose, Regina Albanese; Torres, Marcelo Luis Abramides; Carmona, Maria José Carvalho; Auler, José Otávio Costa

    2012-01-01

    Academic leagues have been consolidated as instruments of medical teaching and for the introducing of medical students to practice of specialties, including anesthesiology. As the role of leagues in the development process of competencies and learning of their students is not well known, the learning of members of an anesthesiology academic league was evaluated after participating in its activities for one year. Students of an anesthesiology academic league were followed up from March to December 2010 and evaluated through objective cognitive tests of multiple choice applied before the beginning of activities and after their conclusion. Attendance in activities and epidemiologic profile of students were correlated with the tests results. Twenty medical students from 3rd to 6th year were analyzed, with an average age of 22.8 (21-26) years. The average participation in the proposed activities was 10.4/13 (80%). The average of right answers on the first test was 8.1/17 (47.6%), and 3rd year students had lower grades (pperformance (pevaluation tests, suggesting that the league is a useful teaching instrument that can provide improved learning of anesthesiology. Participation in activities was connected with improved performance. Activities developed in leagues may have a positive role in students' academic education, more specifically in this article, in anesthesiology. Copyright © 2012 Elsevier Editora Ltda. All rights reserved.

  15. Selected Areas in Cryptography - SAC 2013 : 20th International Conference, Burnaby BC, Canada, August 14-16, 2013 : Revised Selected Papers

    NARCIS (Netherlands)

    Lange, T.; Lauter, K.; Lisonek, P.

    2014-01-01

    This book constitutes the proceedings of the 20th International Conference on Selected Areas in Cryptography, SAC 2013, held in Burnaby, Canada, in August 2013. The 26 papers presented in this volume were carefully reviewed and selected from 98 submissions. They are organized in topical sections

  16. MoViE: Experiences and attitudes—Learning with a mobile social video application

    Directory of Open Access Journals (Sweden)

    Pauliina Tuomi

    2010-10-01

    Full Text Available Digital media is increasingly finding its way into the discussions of the classroom. Particularly interest is placed on mobile learning—the learning and teaching practices done with or via different mobile devices. Learning with the help of mobile devices is increasingly common and it is considered to be one of the 21st century skills children should adapt already in early stages in schools. The article presents both qualitative and quantitative study on mobile social video application, MoViE, as a part of teaching in biology and geography in 8th and 9th grades. The multidisciplinary data was processed to answer the following question: How did the use of mobile videos promote learning? The actual research question is however twofold: On one hand, it studies the use of mobile videos in mobile learning. On the other hand, it sets out to investigate the implementation of mobile video sharing as a part of the teaching and learning activities.

  17. Design Fixation and Cooperative Learning in Elementary Engineering Design Project: A Case Study

    Directory of Open Access Journals (Sweden)

    Yi Luo

    2015-09-01

    Full Text Available This paper presents a case study examining 3rd, 4th and 5th graders’ design fixation and cooperative learning in an engineering design project. A mixed methods instrument, the Cooperative Learning Observation Protocol (CLOP, was adapted to record frequency and class observation on cooperative learning engagement through detailed field notes. Students’ design journals and reflections were also analyzed for an inductive qualitative analysis. The findings indicate three major themes of design fixation: 1 fixation on common features of things; 2 fixation on popular teenage culture; 3 fixation on the first design idea. In the cooperative learning process of elementary engineering design project, although pupils had demonstrated some abilities to solve concrete problems in a logical fashion, the participants encountered a number of obstacles in the group. Dominance, social loafing, and other problems occurring in the group process might have offset certain benefits of cooperative learning. Implications of the findings are also discussed.

  18. Design fixation and cooperative learning in elementary engineering design project: A case study

    Directory of Open Access Journals (Sweden)

    Yi Luo

    2015-09-01

    Full Text Available This paper presents a case study examining 3rd, 4th and 5th graders’ design fixation and cooperative learning in an engineering design project. A mixed methods instrument, the Cooperative Learning Observation Protocol (CLOP, was adapted to record frequency and class observation on cooperative learning engagement through detailed field notes. Students’ design journals and reflections were also analyzed for an inductive qualitative analysis. The findings indicate three major themes of design fixation: 1 fixation on common features of things; 2 fixation on popular teenage culture; 3 fixation on the first design idea. In the cooperative learning process of elementary engineering design project, although pupils had demonstrated some abilities to solve concrete problems in a logical fashion, the participants encountered a number of obstacles in the group. Dominance, social loafing, and other problems occurring in the group process might have offset certain benefits of cooperative learning. Implications of the findings are also discussed.

  19. Numbered head together with scientific approach in geometry learning

    Science.gov (United States)

    Indarti, Dwi; Mardiyana; Pramudya, Ikrar

    2017-12-01

    The aim of this research was to find out the influence of learning model implementation toward student’s achievement in mathematics. This research was using quasi-experimental research. The population of the research was all of 7th grade students in Karanganyar. Sample was taken using stratified cluster random sampling technique. The data collection has been conducted based on students’ mathematics achievement test. The results from the data analysis showed that the learning mathematics by using Numbered Head Together (NHT) learning model with scientific approach improved student’s achievement in mathematics rather than direct learning model particularly in learning object of quadrilateral. Implementation of NHT learning model with scientific approach could be used by the teachers in teaching and learning, particularly in learning object of quadrilateral.

  20. Editorial - Keeping the Learning in Computer-Based Learning

    Directory of Open Access Journals (Sweden)

    William Kilbride

    2002-09-01

    Full Text Available Political rhetoric about knowledge economies and learning societies really ought to be an educationalist's dream. Add to that the revolutionary power of electronic media, and an insatiable hunger for archaeology among the public, archaeology teaching should be well placed to flourish. In England, the Department for Culture Media and Sport has just closed its call for interest in the multi-million pound Culture Online programme. The New Opportunities Fund has already spent fifty million pounds on digitisation alone, while the Heritage Lottery Fund is encouraging heritage agencies to distribute their data sets online. The JISC continues to expand its information environment, investing most recently in virtual learning environments. In Europe, the 6th Framework promises a single European Research Area, and grid technologies allow high quantities of data to empower an information society - supported by the millions of euros already invested in 'e-content'. All of these programmes, and many many more, provide openings for archaeologists to invest in training, teaching and learning. How can archaeology, in particular staff and students in our educational establishments, take best advantage of this information-rich, digitally-empowered learning society?

  1. Profile of mathematics anxiety of 7th graders

    Science.gov (United States)

    Udil, Patrisius Afrisno; Kusmayadi, Tri Atmojo; Riyadi

    2017-08-01

    Mathematics anxiety is one of the important factors affect students mathematics achievement. This present research investigates profile of students' mathematics anxiety. This research focuses on analysis and description of students' mathematics anxiety level generally and its dominant domain and aspect. Qualitative research with case study strategy was used in this research. Subject in this research involved 15 students of 7th grade chosen with purposive sampling. Data in this research were students' mathematics anxiety scale result, interview record, and observation result during both mathematics learning activity and test. They were asked to complete mathematics anxiety scale before interviewed and observed. The results show that generally students' mathematics anxiety was identified in the moderate level. In addition, students' mathematics anxiety during mathematics test was identified in the high level, but it was in the moderate level during mathematics learning process. Based on the anxiety domain, students have a high mathematics anxiety on cognitive domain, while it was in the moderate level for psychological and physiological domains. On the other hand, it was identified in low level for psychological domain during mathematics learning process. Therefore, it can be concluded that students have serious and high anxiety regarding mathematics on the cognitive domain and mathematics test aspect.

  2. Value Development Underlies the Benefits of Parents' Involvement in Children's Learning: A Longitudinal Investigation in the United States and China

    Science.gov (United States)

    Cheung, Cecilia Sin-Sze; Pomerantz, Eva M.

    2015-01-01

    This research examined whether the benefits of parents' involvement in children's learning are due in part to value development among children. Four times over the 7th and 8th grades, 825 American and Chinese children (M age = 12.73 years) reported on their parents' involvement in their learning and their perceptions of the value their parents…

  3. A framework for studying teacher learning by design

    NARCIS (Netherlands)

    Voogt, Joke; McKenney, Susan; Janssen, Fred; Berry, Amanda; Kicken, Wendy; Coenders, Fer

    2012-01-01

    Voogt, J., McKenney, S., Janssen, F., Berry, A., Kicken, W., & Coenders, F. (2012, 2-6 July). A framework for studying teacher learning by design. Paper presentation at the Teachers as Designers of Technology Enhanced Learning pre-conference workshop in conjunction with the ISLS annual meeting,

  4. Active-learning strategies: the use of a game to reinforce learning in nursing education. A case study.

    Science.gov (United States)

    Boctor, Lisa

    2013-03-01

    The majority of nursing students are kinesthetic learners, preferring a hands-on, active approach to education. Research shows that active-learning strategies can increase student learning and satisfaction. This study looks at the use of one active-learning strategy, a Jeopardy-style game, 'Nursopardy', to reinforce Fundamentals of Nursing material, aiding in students' preparation for a standardized final exam. The game was created keeping students varied learning styles and the NCLEX blueprint in mind. The blueprint was used to create 5 categories, with 26 total questions. Student survey results, using a five-point Likert scale showed that they did find this learning method enjoyable and beneficial to learning. More research is recommended regarding learning outcomes, when using active-learning strategies, such as games. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Théories à processus duaux et théories de l’éducation : le cas de l’enseignement de la pensée critique et de la logique

    Directory of Open Access Journals (Sweden)

    Guillaume Beaulac

    2011-05-01

    Full Text Available Plusieurs théories de l’enseignement de la logique et de la pensée critique prennent pour acquis que l’apprentissage théorique, celui des règles formelles par exemple, et son application pratique sont suffisants pour maîtriser les outils enseignés et pour prendre l’habitude de les mettre en usage. Toutefois, tout indique que cet enseignement n’est pas efficace, une conclusion supportée par plusieurs travaux en sciences cognitives. Approcher l’étude de la cognition évolutionnairement avec les théories à processus duaux permet une explication de ces insuffisances, tout en offrant des pistes pour aborder l’enseignement de la pensée critique et de la logique de manière plus efficace. Dans cet article, nous souhaitons présenter cette approche et explorer ces pistes de solution afin de faire quelques recommandations pédagogiques et mettre en place un cadre théorique. Nous présenterons un exemple d’application de ce programme de recherche avec la philosophie pour enfants.Many theories about the teaching of logic and critical thinking take for granted that theoretical learning, the learning of formal rules for example, and its practical application are sufficient to master the tools taught and to take the habit of using them. However, this way of teaching is not efficient, a conclusion supported by much work in cognitive science. Approaching cognition evolutionarily with dual-process theories allows for an explanation of these insufficiencies and offers clues on how we could teach critical thinking and logic more efficiently. In this article, we want to present this approach and explore these leads in order to make some pedagogical recommendations and lay the foundations of a framework. We will put forward an example of the application of this research program with philosophy for children

  6. Prof Rambhajun Sitaram

    African Journals Online (AJOL)

    Buro van die WAT

    read at the Dictionaries in Asia Conference, Hong Kong University of Science and Technology, 26-29 ... in the 19th century. A learner's monolingual dictionary for learning a living .... It is considered a standard dictionary in. Indonesia. There is ...

  7. Learning User Preferences in Ubiquitous Systems: A User Study and a Reinforcement Learning Approach

    OpenAIRE

    Zaidenberg , Sofia; Reignier , Patrick; Mandran , Nadine

    2010-01-01

    International audience; Our study concerns a virtual assistant, proposing services to the user based on its current perceived activity and situation (ambient intelligence). Instead of asking the user to define his preferences, we acquire them automatically using a reinforcement learning approach. Experiments showed that our system succeeded the learning of user preferences. In order to validate the relevance and usability of such a system, we have first conducted a user study. 26 non-expert s...

  8. 30. MPA-Seminar 'Safety and reliability in energy technology' in conjunction with the 9th German-Japanese seminar. Vol. 1 (Papers 1-26)

    International Nuclear Information System (INIS)

    Roos, E.

    2004-01-01

    The 30th MPA-seminar on ''Safety and Availability in Energy Engineering'' was held in conjuction with the 9th German-Japanese Seminar. The 52 contributions were published in two volumes. Volume 1 contains the contributions to the following sessions: fracture mechanics, fatigue, welding, environmental impact and European research projects. Volume 2 contains contributions of sessions 6-9: high-temperature application, modelling-simulation, ageing management and non-destructive testing. (uke)

  9. Towards Mobile Learning Support for the Transition from School to the Workplace

    NARCIS (Netherlands)

    Glahn, Christian; Specht, Marcus; Wishart, Jocelyn

    2011-01-01

    Glahn, C., Specht, M., & Wishart J. (2010). Towards Mobile Learning Support for the Transition from School to the Workplace. Paper presented at the MATEL Workshop in conjunction with the 5th European Conference on Technology Enhanced Learning (EC-TEL 2010): Sustaining TEL: From Innovation to

  10. Modulation of chicken macrophage effector function by Th1/Th2 cytokines

    Science.gov (United States)

    Regulation of macrophage activity by TH1/2 cytokines is important to maintain the balance of immunity to provide adequate protective immunity while avoiding excessive inflammation. IFN-gamma and IL-4 are the hallmark TH1 and TH2 cytokines, respectively. In avian species, information concerning reg...

  11. Down-regulation of Notch signaling pathway reverses the Th1/Th2 imbalance in tuberculosis patients.

    Science.gov (United States)

    Li, Qifeng; Zhang, Hui; Yu, Liang; Wu, Chao; Luo, Xinhui; Sun, He; Ding, Jianbing

    2018-01-01

    Th1/Th2 imbalance to Th2 is of significance in the peripheral immune responses in Tuberculosis (TB) development. However, the mechanisms for Th1/Th2 imbalance are still not well determined. Notch signaling pathway is involved in the peripheral T cell activation and effector cell differentiation. However, whether it affects Th1/Th2 imbalance in TB patients is still not known. Here, we used γ-secretase inhibitor (DAPT) to treat the peripheral blood mononuclear cells (PBMCs) from healthy people or individuals with latent or active TB infection in vitro, respectively. Then, the Th1/Th2 ratios were determined by flow cytometry, and cytokines of IFN-γ, IL-4, IL-10 in the culture supernatant were measured by CBA method. The Notch signal pathway associated proteins Hes1, GATA3 and T-bet were quantitated by real-time PCR or immunoblotting. Our results showed that DAPT effectively inhibited the protein level of Hes1. In TB patients, the Th2 ratio increased in the PBMCs, alone with the high expression of GATA3 and IL-4, resulting in the high ratios of Th2/Th1 and GATA3/T-bet in TB patients. However, Th2 cells ratio decreased after blocking the Notch signaling pathway by DAPT and the Th2/Th1 ratio in TB patients were DAPT dose-dependent, accompanied by the decrease of IL-4 and GATA3. But, its influence on Th1 ratio and Th1 related T-bet and IFN-γ levels were not significant. In conclusion, our results suggest that blocking Notch signaling by DAPT could inhibit Th2 responses and restore Th1/Th2 imbalance in TB patients. Copyright © 2017. Published by Elsevier B.V.

  12. Cunning Pedagogics: The Encounter between the Jesuit Missionaries and Amerindians in Th-Century New France

    Science.gov (United States)

    Welton, Michael

    2005-01-01

    The Jesuit encounter with the Amerindians of the St. Lawrence Valley in Th-century New France provides us with incalculable insights into the inner workings of the "colonial imagination" that believes the objects of instruction have everything to learn and nothing of value to teach. This article explicates how the Jesuits got to know their…

  13. ADAPTATION OF THE STUDENTS' MOTIVATION TOWARDS SCIENCE LEARNING QUESTIONNAIRE TO MEASURE GREEK STUDENTS’ MOTIVATION TOWARDS BIOLOGY LEARNING

    OpenAIRE

    Andressa, Helen; Mavrikaki, Evangelia; Dermitzaki, Irini

    2015-01-01

    The purpose of this study was to investigate students’ motivation towards biology learning and to determine the factors that are related to it: students’ gender and their parents’ occupation (relevant with biology or not) were investigated. The sample of the study consisted of 360 Greek high school students of the 10th grade (178 boys and 182 girls). The data were collected through Students’ Motivation Toward Science Learning (SMTSL) questionnaire. It was found that it was a valid and reliabl...

  14. Observations of A0535 + 26 with the SMM satellite

    Science.gov (United States)

    Sembay, S.; Schwartz, R. A.; Orwig, L. E.; Dennis, B. R.; Davies, S. R.

    1990-01-01

    An examination of archival data from the hard X-ray instruments on the Solar Maximum Mission (SMM) satellite has revealed a previously undetected outburst from the recurrent X-ray transient, A0535 + 26. The outburst occurred in June 1983 and reached a peak intensity of about 2 crab units in the energy range 32-91 keV. The outburst was detected over a span of 18 days, and the pulse period was observed to spin-up with an average rate of about -6 x 10 to the -8th s/s. A recently proposed model for A0535 + 26 has a pulsar powered by a short-lived accretion disk. A thin accretion disk model is fitted to the present data, assuming an orbital period of 111 days. Two solutions to the magnetic moment of the neutron star are derived. The slow rotator solution is more consistent with the model than the fast rotator, on the grounds that the conditions for the formation of an accretion disk are more favorable for a lower magnetic field strength.

  15. Implementing Adaptive Educational Methods with IMS Learning Design

    NARCIS (Netherlands)

    Specht, Marcus; Burgos, Daniel

    2006-01-01

    Please, cite this publication as: Specht, M. & Burgos, D. (2006). Implementing Adaptive Educational Methods with IMS Learning Design. Proceedings of Adaptive Hypermedia. June, Dublin, Ireland. Retrieved June 30th, 2006, from http://dspace.learningnetworks.org

  16. Cytokines in systemic lupus erythematosus: far beyond Th1/Th2 dualism lupus: cytokine profiles.

    Science.gov (United States)

    Guimarães, Poliana Macedo; Scavuzzi, Bruna Miglioranza; Stadtlober, Nicole Perugini; Franchi Santos, Lorena Flor da Rosa; Lozovoy, Marcell Alysson Batisti; Iriyoda, Tatiana Mayumi Veiga; Costa, Neide Tomimura; Reiche, Edna Maria Vissoci; Maes, Michael; Dichi, Isaias; Simão, Andréa Name Colado

    2017-10-01

    The aims of this study were to delineate cytokine profiles of systemic lupus erythematosus (SLE), construct prediction models for diagnosis and disease activity using those profiles, and to examine the associations between TNFB Ncol polymorphism, body mass index (BMI) and vitamin D levels with cytokine levels. Two hundred SLE patients and 196 healthy controls participated in this case-control study. Plasma cytokines levels of tumor necrosis factor (TNF)-α, interferon (IFN)-γ, interleukin (IL)-1β, IL- 4, IL-6, IL-10, IL-12 and IL-17 were measured and cytokines profiles were computed. IL-6, IL-12, IL-17, IFN-γ and IL-10 levels were significantly higher in SLE, while IL-4 was lower in SLE. The Th1/Th2 and Th1+Th17/Th2 profiles were significantly higher in SLE than in healthy controls, whereas there were no significant differences in the proinflammatory cytokine profile (TNFα+IL-6+IL-1β). In total, 90.4% of all subjects were correctly classified using Th1+Th17 profile and IL-10 (positively associated) and IL-4 (negatively associated) as predictor variables (sensitivity=66.7% and specificity=96.9%). In all, 20.9% of the variance in the SLE Disease Activity Index was predicted by the Th1+Th17/Th2 ratio, IL-10 and BMI (all positively) and proinflammatory profile (inversely associated). B1/B1 genotype is accompanied by increased IL-17 and Th17/Th2 ratio, while B1/B2 genotype is accompanied by higher IL-4 and IFNγ values. 25-OH vitamin D was inversely associated with IFN-γ levels. SLE is accompanied by Th1, Th17 and Treg profile and lowered IL-4 production. Lowered vitamin D levels and B1/B1 genotype, but not BMI, contribute to changes in cytokines profiles. Future treatments should target Th1, Th2 and Th17 profiles rather than inflammatory cytokines.

  17. Designing for Learning and Play - The Smiley Model as Framework

    DEFF Research Database (Denmark)

    Weitze, Charlotte Lærke

    2016-01-01

    digital games. The Smiley Model inspired and provided a scaffold or a heuristic for the overall gamified learning design –- as well as for the students’ learning game design processes when creating small games turning the learning situation into an engaging experience. The audience for the experiments......This paper presents a framework for designing engaging learning experiences in games – the Smiley Model. In this Design-Based Research project, student-game-designers were learning inside a gamified learning design - while designing and implementing learning goals from curriculum into the small...... was adult upper secondary general students as well as 7th grade primary school students. The intention with this article is to inspire future learning designers that would like to experiment with integrating learning and play....

  18. Proceedings of the third "international Traveling Workshop on Interactions between Sparse models and Technology" (iTWIST'16)

    DEFF Research Database (Denmark)

    2016-01-01

    The third edition of the "international - Traveling Workshop on Interactions between Sparse models and Technology" (iTWIST) took place in Aalborg, the 4th largest city in Denmark situated beautifully in the northern part of the country, from the 24th to 26th of August 2016. The workshop venue...... learning; Optimization for sparse modelling; Information theory, geometry and randomness; Sparsity? What's next? (Discrete-valued signals; Union of low-dimensional spaces, Cosparsity, mixed/group norm, model-based, low-complexity models, ...); Matrix/manifold sensing/processing (graph, low...

  19. O senso de auto-eficácia e o comportamento orientado para aprendizagem em crianças com queixa de dificuldade de aprendizagem Sense of self-efficacy and behavior oriented towards learning in children with complaint of learning difficulty

    Directory of Open Access Journals (Sweden)

    Paula Cristina Medeiros

    2003-04-01

    Full Text Available Objetiva-se avaliar aspectos do desempenho acadêmico de crianças, relacionando indicadores da produção e do comportamento orientado para aprendizagem com indicadores de percepção do senso de auto-eficácia. Procedeu-se a avaliação por meio do Roteiro de Observação Clínica Comportamental da Criança e do Roteiro de Avaliação do Senso de Auto-Eficácia de 52 crianças, de ambos os sexos, na faixa etária de oito a 12 anos, alunos de 1ª a 4ª série, divididas em: 26 crianças com queixa de dificuldade de aprendizagem, encaminhadas para atendimento psicológico e 26 crianças com bom desempenho acadêmico avaliado por Teste de Desempenho Escolar. Observou-se que as crianças com queixa de dificuldade de aprendizagem, quando comparadas às crianças com bom desempenho, apresentaram diferença estatisticamente significativa; a quanto à produção: atividades de qualidade média; b quanto ao comportamento: baixa capacidade de organização, atenção, iniciativa, decisão, comunicação e interação espontânea; c quanto à percepção: baixo senso de auto-eficácia.The aim of this work has been to assess children's academic performance, relating indicators of production, and behavior oriented towards learning, with indicators of self-efficacy sense perception. Fifty-two children, from 8 and 12 years old, from both sexes have been assessed through the Guideline for Children's Behavioral Clinical Observation and through the Guideline for the Assessment of Self-efficacy Sense. They had been attending from the 1st to the 4th primary school levels and were divided in: 26 children with complaint of learning difficulty, forwarded to psychological attendance and 26 children with good academic performance assessed through the School Performance Test. It has been seen that the children with complaint of learning difficulty, as compared to children with good academic performance, presented statistically significant difference in the: a

  20. 10th Australian conference on nuclear techniques of analysis. Proceedings

    International Nuclear Information System (INIS)

    1998-01-01

    These proceedings contains abstracts and extended abstracts of 80 lectures and posters presented at the 10th Australian conference on nuclear techniques of analysis hosted by the Australian National University in Canberra, Australia from 24-26 of November 1997. The conference was divided into sessions on the following topics : ion beam analysis and its applications; surface science; novel nuclear techniques of analysis, characterization of thin films, electronic and optoelectronic material formed by ion implantation, nanometre science and technology, plasma science and technology. A special session was dedicated to new nuclear techniques of analysis, future trends and developments. Separate abstracts were prepared for the individual presentation included in this volume

  1. 10th Australian conference on nuclear techniques of analysis. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    These proceedings contains abstracts and extended abstracts of 80 lectures and posters presented at the 10th Australian conference on nuclear techniques of analysis hosted by the Australian National University in Canberra, Australia from 24-26 of November 1997. The conference was divided into sessions on the following topics : ion beam analysis and its applications; surface science; novel nuclear techniques of analysis, characterization of thin films, electronic and optoelectronic material formed by ion implantation, nanometre science and technology, plasma science and technology. A special session was dedicated to new nuclear techniques of analysis, future trends and developments. Separate abstracts were prepared for the individual presentation included in this volume.

  2. Distribution of Th-230 and Th-228 in food (I)

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hee Dong; Kim, Wan; Lim, X. J.; Choi, M. S.; Kim, C. J.; Zheng, Y. Z. [Kyungpook National Univ., Daegu (Korea, Republic of); Kim, Do Sung [Daegu Univ., Daegu (Korea, Republic of)

    2003-03-15

    Natural radioisotopes contained in foods can enter the human body by ingestion and contribute to internal doses to the population. It is necessary to measure the concentration of natural radioisotopes especially thorium in Korean foods and estimate the internal doses. In this study, we have established the thorium measuring process based on the thorium extraction chemical process and alpha spectroscopic method. The concentration of Th-228, Th-230 and Th-232 in Korean milk, meats(pork, beef and chicken) and grain (wheat, bean and rice) are measured and internal doses are estimated.

  3. Modeling the Relations among Students' Epistemological Beliefs, Motivation, Learning Approach, and Achievement

    Science.gov (United States)

    Kizilgunes, Berna; Tekkaya, Ceren; Sungur, Semra

    2009-01-01

    The authors proposed a model to explain how epistemological beliefs, achievement motivation, and learning approach related to achievement. The authors assumed that epistemological beliefs influence achievement indirectly through their effect on achievement motivation and learning approach. Participants were 1,041 6th-grade students. Results of the…

  4. An Analysis of the Educational Potential of Augmented Reality Games for Learning

    NARCIS (Netherlands)

    Schmitz, Birgit; Specht, Marcus; Klemke, Roland

    2013-01-01

    Schmitz, B., Specht, M., & Klemke, R. (2012). An Analysis of the Educational Potential of Augmented Reality Games for Learning. In M. Specht, J. Multisilta, & M. Sharples (Eds.), Proceedings of the 11th World Conference on Mobile and Contextual Learning 2012 (pp. 140-147). October, 16-18, 2012,

  5. Effect of xanthohumol on Th1/Th2 balance in a breast cancer mouse model.

    Science.gov (United States)

    Zhang, Wenchao; Pan, Yanlong; Gou, Panhong; Zhou, Cheng; Ma, Lianqing; Liu, Qiming; Du, Yuping; Yang, Jinbo; Wang, Qin

    2018-01-01

    Xanthohumol (XN), a prenylflavonoid found in the hop plant, Humulus lupulus, exhibits a variety of biological activities. Numerous studies have reported that XN inhibits the growth of many types of cancer cells, but the effects of XN on tumor immunity have not yet been studied. We explored the effect of XN on Th1/Th2 balance and the underlying mechanism based on a BALB/c-4T1 breast cancer mouse model. The results showed that XN significantly slowed down tumor growth and inhibited expression of antitumor proliferation protein Ki-67 as well as breast cancer-specific marker cancer antigen 15-3 (CA15-3). Flow cytometric analysis revealed that XN enhanced the secretion of perforin, granzyme B and increased the ratio of CD8+/CD25+. ELISA analysis of cytokine results demonstrated that XN obviously upregulated Th1 cytokines, while downregulated Th2 cytokines. Th1/Th2 ratio analysis by flow cytometry illustrated that XN regulated the balance drift to Th1 polarization. Western blotting and immunohistochemistry (IHC) results manifested that XN induced expression of T-bet, a Th1-specific transcription factor. Furthermore, we found that XN significantly promoted the phosphorylation of signal transducer and activator of transcription (STAT)4. Our results demonstrated that XN promoted Th1/Th2 balance towards Th1 polarization, and STAT4 may play a positive role in the regulation of Th1/Th2 cytokines by XN.

  6. Inductive Learning and Theory Testing: Applications in Finance

    OpenAIRE

    Zimmermann, Tom

    2015-01-01

    This thesis explores the opportunities for economic research that arise from importing empirical methods from the field of machine learning. Chapter 1 applies inductive learning to cross-sectional asset pricing. Researchers have documented over three hundred variables that can explain differences in cross-sectional stock returns. But which ones contain independent information? Chapter 1 develops a framework, deep conditional portfolio sorts, that can be used to answer this question and th...

  7. Machine learning \\& artificial intelligence in the quantum domain

    OpenAIRE

    Dunjko, Vedran; Briegel, Hans J.

    2017-01-01

    Quantum information technologies, and intelligent learning systems, are both emergent technologies that will likely have a transforming impact on our society. The respective underlying fields of research -- quantum information (QI) versus machine learning (ML) and artificial intelligence (AI) -- have their own specific challenges, which have hitherto been investigated largely independently. However, in a growing body of recent work, researchers have been probing the question to what extent th...

  8. The 30th Anniversary of Campylobacter, Helicobacter and Related Organisms Workshops – What Have We Learned In Three Decades?

    Directory of Open Access Journals (Sweden)

    Christine M Szymanski

    2012-02-01

    Full Text Available As we commemorate the 30th anniversary of the Campylobacter, Helicobacter and Related Organisms (CHRO workshops with this special Frontiers edition, we look back upon three decades of research and provide some highlights from the 16th International CHRO meeting. As Martin Skirrow noted, Elizabeth King was the first to isolate campylobacters in the 1950’s, although Escherich himself provided drawings of these fecal organisms back in the 1880’s. Helicobacter is a more recent organism, first described to be the causative agent of stomach ulcers at a CHRO meeting by Barry Marshall and Robin Warren – who then later received the Nobel Prize for their findings that bacteria could cause diseases previously believed to be caused by human factors. Studies of the intersection of host microbial ecology and pathogen infection have been pioneered by scientists such as Brett Finlay, who described his current work on this topic. And as general antibiotics are routinely administered, we see a rise in bacterial antibiotic resistance. Julian Davies emphasized that there is a growing need for the development of new bioactive compounds on the horizon as we advance our knowledge on these pathogens. The first genome of C. jejuni was published in 2000; now one decade later we have 30 Campyobacter taxa sequenced, and this number continues to rise quickly. However, we continue to obtain unexpected results as a pioneer in CHRO research, Martin Blaser explained – i.e., although H. pylori is now classified as a level I carcinogen, there may be benefits to carrying this organism as part of your normal flora. Other findings indicate that Campylobacters and Helicobacters do not follow classic paradigms of other well-characterized gastrointestinal pathogens. And we are learning that there is a whole world of interesting related organisms beyond C. jejuni and H. pylori. This review summarizes some of the history of CHRO research and the exciting directions ahead.

  9. Radiation-induced decrease of CD8+ dendritic cells contributes to Th1/Th2 shift.

    Science.gov (United States)

    Liu, Hu; Li, Bailong; Jia, Xiaojing; Ma, Yan; Gu, Yifeng; Zhang, Pei; Wei, Qun; Cai, Jianming; Cui, Jianguo; Gao, Fu; Yang, Yanyong

    2017-05-01

    Exposure to ionizing radiation (IR) often reduce the helper T (Th) 1 like function, resulting in a Th1/Th2 imbalance, which could affect the efficacy of cancer radiotherapy. As the most potent antigen presenting cells, dendritic cells (DC) can be divided into several subsets with specialized function. However, there is no literature covering the changes of DC subsets and their roles in immune regulation in response to IR. In the present study, we were aimed to investigate the changes of DC subsets after IR and its relationship with Th1/Th2 immunity. We found a significant decrease of BDCA3+DC in the blood of patients treated with radiotherapy. CD8+DC, a mouse equivalent of human BDCA3+DC, was also found decreased in mice spleen, peripheral blood and lymph node tissues after irradiation. As CD8+DC mainly induce Th1 immunity, we tested the changes of Th1/Th2 response and found that IR caused a repression of Th1 immunity, indicating a possible role of CD8+DC in radiation-induced Th1/Th2 imbalance. We also found that a CD8+DC-inducing cytokine, Fms-like tyrosine kinase 3 ligand (FLT3 ligand), restored CD8+DC and reversed Th1/Th2 shift. And then we found that bone marrow cells from irradiated mice differentiated into less CD8+DC, which was also protected by FLT3 ligand. In conclusion, our data showed that IR induced a decrease of CD8+DC and Th1/Th2 shift, which was reversed by Flt3 ligand treatment, suggesting a novel mechanism for radiation-induced immunosuppression. Copyright © 2017. Published by Elsevier B.V.

  10. Structural phase stability of ThSb and ThAs under pressure

    International Nuclear Information System (INIS)

    Venkatasubramaniam, K.; Rajagopalan, M.; Palanivel, B.; Kalpana, G.

    1997-01-01

    The high-pressure behaviour of thorium monopnictides is of considerable interest as these systems exhibit structural phase transitions under pressure. At ambient conditions these compounds crystallize in the NaCl-type(B1) structure. Experiments show that with the application of pressure these compounds transform to the CsCl-type (B2) structure. ThSb and ThAs are found to exhibit B1-B2 transition in the pressure range between 9-12 GPa and 1826 GPa respectively. In this work, we present the electronic and high-pressure behaviour of ThAs and ThSb performed using the tight-binding linear muffin-tin orbital method. The total energies within the atomic sphere approximation were calculated as a function of volume for both the B1 and B2 structures. The total energy calculations reveal that both ThSb and ThAs are stable in the B1 structure at ambient conditions and undergo structural transition to the B2 structure at pressures 78 and 240 kbar respectively, which are in good agreement with the experimental values. The calculated values of equilibrium lattice parameter and the transition pressure are found to be in good agreement with the experimental results. (author)

  11. Improved Student Reasoning About Carbon-Transforming Processes Through Inquiry-Based Learning Activities Derived from an Empirically Validated Learning Progression

    Science.gov (United States)

    JW, Schramm; Jin, H.; Keeling, EG; Johnson, M.; Shin, HJ

    2017-05-01

    This paper reports on our use of a fine-grained learning progression to assess secondary students' reasoning through carbon-transforming processes (photosynthesis, respiration, biosynthesis). Based on previous studies, we developed a learning progression with four progress variables: explaining mass changes, explaining energy transformations, explaining subsystems, and explaining large-scale systems. For this study, we developed a 2-week teaching module integrating these progress variables. Students were assessed before and after instruction, with the learning progression framework driving data analysis. Our work revealed significant overall learning gains for all students, with the mean post-test person proficiency estimates higher by 0.6 logits than the pre-test proficiency estimates. Further, instructional effects were statistically similar across all grades included in the study (7th-12th) with students in the lowest third of initial proficiency evidencing the largest learning gains. Students showed significant gains in explaining the processes of photosynthesis and respiration and in explaining transformations of mass and energy, areas where prior research has shown that student misconceptions are prevalent. Student gains on items about large-scale systems were higher than with other variables (although absolute proficiency was still lower). Gains across each of the biological processes tested were similar, despite the different levels of emphasis each had in the teaching unit. Together, these results indicate that students can benefit from instruction addressing these processes more explicitly. This requires pedagogical design quite different from that usually practiced with students at this level.

  12. 27 CFR 22.104 - Educational organizations, colleges of learning, and scientific universities.

    Science.gov (United States)

    2010-04-01

    ..., colleges of learning, and scientific universities. 22.104 Section 22.104 Alcohol, Tobacco Products and... OF TAX-FREE ALCOHOL Use of Tax-Free Alcohol § 22.104 Educational organizations, colleges of learning... income tax under 26 U.S.C. 501(a). (b) Colleges of learning. Colleges of learning, for the purposes of...

  13. Th1, Th17, CXCL16 and homocysteine elevated after intracranial and cervical stent implantation.

    Science.gov (United States)

    Tang, Yanyan; Wei, Yunfei; Ye, Ziming; Qin, Chao

    2017-08-01

    The presence of Th1 and Th17 cells has been observed as major inducers in inflammation and immune responses associated stenting. However, there is rare data on the impact of Th1, Th17, CXCL16 and homocysteine after cerebral stent implantation. Here, we performed the statistical analysis to first evaluate the variation of the Th17and Th1 cells and their related cytokines, CXCL16 and homocysteine in the peripheral blood of patients with cerebral stenting. The flow cytometry was used to detect the proportion of Th1 and Th17 cells in peripheral blood mononuclear cells (PBMCs). The enzyme-linked immunosorbent assay was used to measure the serum concentrations of IFN-γ, IL-17 and CXCL16. Plasma homocysteine was examined by immunoturbidimetry. The level of Th1, CXCL16 and homocysteine showed an increase at 3 d, followed by the continuous decrease at 7 d and 3 months. The frequency of Th17 cells increased to a peak at three days, and subsequently decreased with a higher level than baseline. Our data revealed that the variation in Th1, Th17, CXCL16 and homocysteine in peripheral blood of patients with stenting may be implicated in inflammation after intracranial and cervical stent implantation. A better understanding of these factors will provide help for further drug design and clinical therapy.

  14. Effects of PARP-1 Deficiency on Th1 and Th2 Cell Differentiation

    Directory of Open Access Journals (Sweden)

    M. Sambucci

    2013-01-01

    Full Text Available T cell differentiation to effector Th cells such as Th1 and Th2 requires the integration of multiple synergic and antagonist signals. Poly(ADP-ribosylation is a posttranslational modification of proteins catalyzed by Poly(ADP-ribose polymerases (PARPs. Recently, many reports showed that PARP-1, the prototypical member of the PARP family, plays a role in immune/inflammatory responses. Consistently, its enzymatic inhibition confers protection in several models of immune-mediated diseases, mainly through an inhibitory effect on NF-κB (and NFAT activation. PARP-1 regulates cell functions in many types of immune cells, including dendritic cells, macrophages, and T and B lymphocytes. Our results show that PARP-1KO cells displayed a reduced ability to differentiate in Th2 cells. Under both nonskewing and Th2-polarizing conditions, naïve CD4 cells from PARP-1KO mice generated a reduced frequency of IL-4+ cells, produced less IL-5, and expressed GATA-3 at lower levels compared with cells from wild type mice. Conversely, PARP-1 deficiency did not substantially affect differentiation to Th1 cells. Indeed, the frequency of IFN-γ+ cells as well as IFN-γ production, in nonskewing and Th1-polarizing conditions, was not affected by PARP-1 gene ablation. These findings demonstrate that PARP-1 plays a relevant role in Th2 cell differentiation and it might be a target to be exploited for the modulation of Th2-dependent immune-mediated diseases.

  15. Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties.

    Science.gov (United States)

    Prajeeth, Chittappen K; Kronisch, Julius; Khorooshi, Reza; Knier, Benjamin; Toft-Hansen, Henrik; Gudi, Viktoria; Floess, Stefan; Huehn, Jochen; Owens, Trevor; Korn, Thomas; Stangel, Martin

    2017-10-16

    Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously, we have shown that only Th1 but not Th17 effectors activate microglia. However, it is not clear which cells are targets of Th17 effectors in the CNS. To understand the effects driven by Th17 cells in the CNS, we induced experimental autoimmune encephalomyelitis in wild-type mice and CD4 + T cell-specific integrin α4-deficient mice where trafficking of Th1 cells into the CNS was affected. We compared microglial and astrocyte response in the brain and spinal cord of these mice. We further treated astrocytes with supernatants from highly pure Th1 and Th17 cultures and assessed the messenger RNA expression of neurotrophic factors, cytokines and chemokines, using real-time PCR. Data obtained was analyzed using the Kruskal-Wallis test. We observed in α4-deficient mice weak microglial activation but comparable astrogliosis to that of wild-type mice in the regions of the brain populated with Th17 infiltrates, suggesting that Th17 cells target astrocytes and not microglia. In vitro, in response to supernatants from Th1 and Th17 cultures, astrocytes showed altered expression of neurotrophic factors, pro-inflammatory cytokines and chemokines. Furthermore, increased expression of chemokines in Th1- and Th17-treated astrocytes enhanced recruitment of microglia and transendothelial migration of Th17 cells in vitro. Our results demonstrate the delicate interaction between T cell subsets and glial cells and how they communicate to mediate their effects. Effectors of Th1 act on both microglia and astrocytes whereas Th17 effectors preferentially target astrocytes to promote neuroinflammation.

  16. Cloning and Characterization of ThSHRs and ThSCR Transcription Factors in Taxodium Hybrid 'Zhongshanshan 406'.

    Science.gov (United States)

    Wang, Zhiquan; Yin, Yunlong; Hua, Jianfeng; Fan, Wencai; Yu, Chaoguang; Xuan, Lei; Yu, Fangyuan

    2017-07-20

    Among the GRAS family of transcription factors, SHORT ROOT (SHR) and SCARECROW (SCR) are key regulators of the formation of root tissues. In this study, we isolated and characterized two genes encoding SHR proteins and one gene encoding an SCR protein: ThSHR1 (Accession Number MF045148), ThSHR2 (Accession Number MF045149) and ThSCR (Accession Number MF045152) in the adventitious roots of Taxodium hybrid 'Zhongshanshan'. Gene structure analysis indicated that ThSHR1 , ThSHR2 and ThSCR are all intron free. Multiple protein sequence alignments showed that each of the corresponding proteins, ThSHR1, ThSHR2 and ThSCR, contained five well-conserved domains: leucine heptad repeat I (LHRI), the VHIID motif, leucine heptad repeat II (LHR II), the PFYRE motif, and the SAW motif. The phylogenetic analysis indicated that ThSCR was positioned in the SCR clade with the SCR proteins from eight other species, while ThSHR1 and ThSHR2 were positioned in the SHR clade with the SHR proteins from six other species. Temporal expression patterns of these genes were profiled during the process of adventitious root development on stem cuttings. Whereas expression of both ThSHR2 and ThSCR increased up to primary root formation before declining, that of ThSHR1 increased steadily throughout adventitious root formation. Subcellular localization studies in transgenic poplar protoplasts revealed that ThSHR1, ThSHR2 and ThSCR were localized in the nucleus. Collectively, these results suggest that the three genes encode Taxodium GRAS family transcription factors, and the findings contribute to improving our understanding of the expression and function of SHR and SCR during adventitious root production, which may then be manipulated to achieve high rates of asexual propagation of valuable tree species.

  17. Trace analysis of U, Th and other heavy metals in high purity aluminium with isotope dilution mass spectrometry

    International Nuclear Information System (INIS)

    Beer, B.; Heumann, K.G.

    1992-01-01

    A method for the determination of very low concentrations of U, Th, Fe, Zn, Tl, Cd, Cu and Ag in high purity aluminium with isotope dilution mass spectrometry (IDMS) is developed using a compact and cost-efficient thermal ionization quadrupole mass spectrometer. The detection limits obtained are (in ng/g):U=0.018, Th=0.06, Fe=82, Zn=86, Tl=0.2, Cd=4, Cu=1, Ag=2.6. By this method it is possible to determine the α-emitters U and Th in aluminium down to the sub-ng/g level with good precision of 0.4-10% and 0.5-5%, respectively. The results should also be accurate because IDMS is a reliable analytical method. The dissolution of aluminium is carried out by aqua regia followed by the trace/matrix separation and the isolation of the trace elements by anion exchange chromatography (U, Th, Zn, Tl, Cd), electrodeposition (Cu, Ag) and extraction (Fe). Different aluminium samples are analysed by IDMS and the results are compared with those of other methods. (orig.)

  18. Immunomodulation Mechanism of Antidepressants: Interactions between Serotonin/Norepinephrine Balance and Th1/Th2 Balance

    Science.gov (United States)

    Martino, Matteo; Rocchi, Giulio; Escelsior, Andrea; Fornaro, Michele

    2012-01-01

    Neurotransmitters and hormones regulate major immune functions, including the selection of T helper (Th)1 or Th2 cytokine responses, related to cell-mediated and humoral immunity, respectively. A role of imbalance and dynamic switching of Th1/Th2 system has been proposed, with relative displacement of the immune reserve in relation to complex interaction between Th1/Th2 and neuro-hormonal balance fluctuations, in the pathogenesis of various chronic human diseases, probably also including psychiatric disorders. Components of the stress system such as norepinephrine (NE) and glucocorticoids appear to mediate a Th2 shift, while serotonin (5-HT) and melatonin might mediate a Th1 shift. Some antidepressants would occur affecting these systems, acting on neurotransmitter balance (especially the 5-HT/NE balance) and expression levels of receptor subtypes, which in turn affect cytokine production and relative Th1/Th2 balance. It could be therefore hypothesized that the antidepressant-related increase in NE tone enhances the Th2 response, while the decrease in NE tone or the increase in 5-HT tone enhances the Th1 response. However, the neurotransmitter and Th1/Th2 balance modulation could be relative, aiming to restore physiological levels a previous imbalance in receptor sensitivity and cytokine production. The considerations on neuro-immunomodulation could represent an additional aid in the study of pathophysiology of psychiatric disorders and in the choice of specific antidepressants in specific clusters of symptoms, especially in comorbidity with internal pathologies. Furthermore limited data, reviewed here, have shown the effectiveness of some antidepressants as pure immunomodulators. However, these considerations are tentative and require experimental confirmation or refutation by future studies. PMID:23204981

  19. Improving Problem Solving Skill and Self Regulated Learning of Senior High School Students through Scientific Approach using Quantum Learning strategy

    Directory of Open Access Journals (Sweden)

    M Sudirman

    2017-12-01

    Full Text Available This research is quasi experiment with control group pretest-postest design. The sampel in this research using the techique of purposive sampling so the samples used were two classes of the 11th grade students of SMAN 14 Bandung in the academic year 2017/2018. The experiment group uses saintific approach using Quantum Learning strategy and control group uses saintific approach. In collecting the data the researcher will use the test of problem solving ability and self regulated learning as the instrument. The aims of this research are to:1find out the improvement of students mathematical problem solving through scientific approach using Quantum Learning study, 2 find out students self regulated learning through scientific approach using Quantum Learning.

  20. AN OVERVIEW OF CLOUD COMPUTING FOR E-LEARNING WITH ITS KEY BENEFITS

    OpenAIRE

    Mansi Bosamia

    2018-01-01

    Education is a necessary human virtue and essential for society because it reflects the personality of the human being in our society. The effective way of teaching gives the quality of education and advance learning such as e-learning to the learners and also a high quality of teaching to the tutors. Information Technology (IT) plays a significant role in field of education. Now days, E-learning and M-learning have become very popular trends of the education technology riot. E-Learning is th...

  1. Selected Lectures of the 13th International Workshop on Neonatology; Cagliari (Italy); October 25th-28th, 2017

    OpenAIRE

    --- Various Authors

    2017-01-01

    Selected Lectures of the 13th International Workshop on Neonatology • The power of Epigenetics • Twins: identical but different • Cagliari (Italy) • October 25th-28th, 2017LECT 1. ASPHYXIA IN THE THIRD MILLENNIUM: FROM VIRGINIA APGAR TO METABOLOMICS • O.D. SaugstadLECT 2. INTRAPARTUM FETAL MONITORING: WHERE ARE WE NOW? • D. Ayres-de-CamposLECT 3. THERAPEUTIC HYPOTHERMIA: REVISED IN­DI­CA­TIONS • E. SalibaLECT 4. ANTIBIOTICS PRESCRIPTION IN NEONATAL INTENSIVE CARE UNIT • G. DimitriouLECT 5. CH...

  2. Modeling of oxygen incorporation in Th, ThC, and ThN by density functional theory calculations

    Science.gov (United States)

    Pérez Daroca, D.; Llois, A. M.; Mosca, H. O.

    2017-12-01

    Oxygen incorporation in nuclear fuel materials is an important issue deserving investigation due to its influence on thermophysical and structural properties. Even if there has been a renewed interest in thorium and thorium compounds in the last years, there is still not much research done on this topic. In this work, we study, by means of density functional theory calculations, the incorporation of oxygen in Th, ThC, and ThN. We analyze the electronic structure finding a characteristic peak to be attributed to oxygen incorporation. We also calculate incorporation and solution energies and obtain migration energies of oxygen through different paths finding that migration through vacancy sites is more energetically favorable than through interstitial ones.

  3. The Effect of Case Teaching on Meaningful and Retentive Learning When Studying Genetic Engineering

    Science.gov (United States)

    Güccük, Ahmet; Köksal, Mustafa Serdar

    2017-01-01

    The purpose of this study is to investigate the effects of case teaching on how students learn about genetic engineering, in terms of meaningful learning and retention of learning. The study was designed as quasi-experimental research including 63 8th graders (28 boys and 35 girls). To collect data, genetic engineering achievement tests were…

  4. Gluten-free diet does not influence the occurrence and the Th1/Th17-Th2 nature of immune-mediated diseases in patients with coeliac disease.

    Science.gov (United States)

    Imperatore, Nicola; Rispo, Antonio; Capone, Pietro; Donetto, Sara; De Palma, Giovanni Domenico; Gerbino, Nicolò; Rea, Matilde; Caporaso, Nicola; Tortora, Raffaella

    2016-07-01

    Coeliac disease (CD) is the most common Th1-mediated enteropathy, frequently associated with other immune-mediated disorders (IMD). To evaluate: (1) the prevalence of IMD at the time of and after CD diagnosis; (2) a possible change in immune response to gluten free diet (GFD); (3) the potential role of GFD in reducing and/or preventing IMD in CD. Prospective study including all consecutive adult CD patients who underwent investigations for Th1-Th17/Th2-IMD at the time of CD diagnosis and after a 5-year follow-up period. 1255 CD were enrolled. Of these, 257 patients (20.5%) showed IMD at the time of CD diagnosis, with 58.4% presenting a Th1/Th17-IMD. After a 5-year follow-up period, 682 patients (54.3%) showed new IMD despite GFD. Of these, 57.3% presented a Th1/Th17-IMD and 42.7% a Th2-IMD (p=0.8). When compared the prevalence of each type of IMD before and after CD diagnosis, we did not identify any significant "switch" from Th1/Th17- to Th2-IMD or vice versa. The number of patients with Th1/Th17- and/or Th2-IMD increased during the GFD period (20.5% vs 54.3%; p<0.01; OR 1.9). The prevalence of IMD at the time of CD diagnosis is high and it seems to increase in the follow-up period despite GFD. Copyright © 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  5. Proceedings of the 5th International Conference on Designs for Learning

    DEFF Research Database (Denmark)

    papers. The accepted papers revolve around a broad range of research subjects and practices within the conference theme. These include methodological questions, discussions of design-based research, presentations of educational designs and discussions of perspectives on designs for learning as self-regulated...

  6. 26th National Neurotrauma Symposium

    Science.gov (United States)

    2008-12-31

    Sanchez Alvaro I., Puyana Juan C., Fabio Anthony, Adelson P. David 81 COMPARATIVE NEUROPROTECTIVE EFFECTS OF CYCLOSPORIN A AND NIM811, A NON...Xiangbai, Fabio Anthony, Yuan Zhifang, Niyonkuru Christian, Wagner Amy 99 ACTIVATION OF MITOCHONDRIAL UNCOUPLING PROTEINS BY POLYUNSATURATED FATTY...Metabolism/Physiological Assessments TBI Mitchell Cohen University of California, San Francisco Ferguson Adam, Cohen Mitchell, Morabito Diane

  7. The Effectiveness of Cooperative Learning Model of Pair Checks Type on Motivation and Mathematics Learning Outcomes of 8th Grade Junior High School Students

    Directory of Open Access Journals (Sweden)

    Wahyu Budi Wicaksono

    2017-08-01

    Full Text Available The purpose of this research was to know the effectiveness of Pair Checks cooperative model towards students’ learning result and learning motivation of eight grade. Population of this research were students of eight grade Junior High School 2 Pati in the academic year 2016/1017. The research used cluster random sampling technique.Where the selected samples were students of class VIII H as experimental class and class VIII G as control class. The data collected by the method of documentation, test methods, and scale methods. The analyzed of data used completeness test and average different test. The results showed that: (1 students’ learning result who join Pair Checks cooperative model have classical study completeness; (2 students’ mathematics learning result who join Pair Checks cooperative model is better than students mathematics learning result who join ekspository learning; (3 students’ learning motivation who join Pair Checks cooperative model is better than students’ learning motivation who join ekspository learning.

  8. The roles of electronic books in the transformation of learning and instruction

    NARCIS (Netherlands)

    Huang, Ronghuai; Chen, Nian-Shing; Kang, Myunghee; McKenney, Susan; Churchill, Daniel

    2014-01-01

    Huang, R., Chen, N., Kang, M. McKenney, S. & Churchill, D. (2013). The roles of electronic books in the transformation of learning and instruction. In N. Chen, R. Huang, Kinshuk, Y. Li, D. G. Sampson (Eds.) Proceedings of the IEEE 13th International Conference on Advanced Learning Technologies

  9. Student Restraints to Reform: Conceptual Change Issues in Enhancing Students' Learning Processes.

    Science.gov (United States)

    Thomas, Gregory P.

    1999-01-01

    Describes a teacher-researcher's investigation into barriers to student adoption of an alternative referent for learning and its consequential learning strategies in an 11th-grade chemistry class. Suggests that various contextual factors influenced students' willingness to adopt the alternative referent, and that students' beliefs, trust of the…

  10. Game based learning for 21st century transferable skills: challenges and opportunities

    NARCIS (Netherlands)

    Bellotti, Francesco; Bottino, Rosa Maria; Nadolski, Rob; Fernández Manjón, Baltasar

    2012-01-01

    Bellotti, F., Bottino, R. M., Nadolski, R. J., & Fernández Manjón, B. (2012, 4-6 July). Game based learning for 21st century transferable skills: challenges and opportunities. Presentation at the Workshop Game based learning for 21st century transferable skills: challenges and opportunities, 12th

  11. Reflection on Cuboid Net with Mathematical Learning Quality

    Science.gov (United States)

    Sari, Atikah; Suryadi, Didi; Syaodih, Ernawulan

    2017-09-01

    This research aims to formulate an alternative to the reflection in mathematics learning activities related to the activities of the professionalism of teachers motivated by a desire to improve the quality of learning. This study is a qualitative study using the Didactical Design research. This study was conducted in one of the elementary schools. The data collection techniques are triangulation with the research subject is teacher 5th grade. The results of this study indicate that through deep reflection, teachers can design learning design in accordance with the conditions of the class. Also revealed that teachers have difficulty in choosing methods of learning and contextual learning media. Based on the implementation of activities of reflection and make the learning design based on the results of reflection can be concluded that the quality of learning in the class will develop.

  12. CopperCore Service Integration, Integrating IMS Learning Design and IMS Question and Test Interoperability

    NARCIS (Netherlands)

    Vogten, Hubert; Martens, Harrie; Nadolski, Rob; Tattersall, Colin; Van Rosmalen, Peter; Koper, Rob

    2006-01-01

    Vogten, H., Martens, H., Nadolski, R., Tattersall, C., Rosmalen, van, P., Koper, R., (2006). CopperCore Service Integration, Integrating IMS Learning Design and IMS Question and Test Interoperability. Proceedings of the 6th IEEE International Conference on Advanced Learning Technologies (pp.

  13. Distribution of Th-230 and Th-228 in foods(II)

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hee Dong; Kim, Wan; Lim, S. K.; Lee, S. A.; Choi, M. S.; Zheng, Y. C. [Kyungpook National Univ., Daegu (Korea, Republic of); Kim, Do Sung [Daegu Univ., Daegu (Korea, Republic of)

    2004-02-15

    Natural radioisotopes contained in foods can enter the human body by ingestion and contribute to internal doses to the population. It is necessary to measure the concentration of natural radioisotopes especially thorium in Korean foods and estimate the internal doses. In this study, we have established the thorium measuring process based on the thorium extraction chemical process and alpha spectroscopic method. The concentration of Th-228, Th-230 and Th-232 in Korean vegetables (potato, sweet potato, radish, cabbage, hot pepper, garlic, onion and pumpkin) and fruits(apple, persimmon, orange, pear, grape) are measured and their internal doses are estimated.

  14. Distribution of Th-230 and Th-228 in foods(II)

    International Nuclear Information System (INIS)

    Kang, Hee Dong; Kim, Wan; Lim, S. K.; Lee, S. A.; Choi, M. S.; Zheng, Y. C.; Kim, Do Sung

    2004-02-01

    Natural radioisotopes contained in foods can enter the human body by ingestion and contribute to internal doses to the population. It is necessary to measure the concentration of natural radioisotopes especially thorium in Korean foods and estimate the internal doses. In this study, we have established the thorium measuring process based on the thorium extraction chemical process and alpha spectroscopic method. The concentration of Th-228, Th-230 and Th-232 in Korean vegetables (potato, sweet potato, radish, cabbage, hot pepper, garlic, onion and pumpkin) and fruits(apple, persimmon, orange, pear, grape) are measured and their internal doses are estimated

  15. Examining Opportunity-to-Learn and Success in High School Mathematics Performance in California under NCLB

    Science.gov (United States)

    Gavrilovic, Daniel Miodrag

    2013-01-01

    The No Child Left Behind Act of 2001 has put many schools under a lot of pressure to meet its high demands. In this quantitative study, the effects that the NCLB act has had on students' opportunity to learn (OTL) and Subject Level Success (SS) from 2004 to 2012 in 9th, 10th, and 11th grade math coursework (Algebra 1, Geometry, Algebra 2, and…

  16. Open Contents Modules Available for E-Learning Multimedia Cartography and Location Based Services

    Directory of Open Access Journals (Sweden)

    Nedjeljko Frančula

    2010-12-01

    Full Text Available Swiss Virtual Campus (SVC is a federal program, which began in 2000th and was completed in 2008th. Its goal was to improve Internet-based learning in Swiss higher education institutions. One of the projects within the SVC was dedicated to cartography: CartouCHe (Cartography for Swiss Higher Education.

  17. Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney.

    Science.gov (United States)

    Nastase, Madalina-Viviana; Zeng-Brouwers, Jinyang; Beckmann, Janet; Tredup, Claudia; Christen, Urs; Radeke, Heinfried H; Wygrecka, Malgorzata; Schaefer, Liliana

    2017-12-15

    Th1 and Th17 cells, T helper (Th) subtypes, are key inducers of renal fibrosis. The molecular mechanisms of their recruitment into the kidney, however, are not well understood. Here, we show that biglycan, a proteoglycan of the extracellular matrix, acting in its soluble form as a danger signal, stimulates autonomously the production of Th1 and Th17 chemoattractants CXCL10 and CCL20 in macrophages. In the presence of IFNγ, biglycan synergistically stimulates CXCL9. In macrophages deficient for TLR2, TLR4, and their adaptor molecules MyD88 or TRIF, we identified highly selective mechanisms of biglycan-dependent Th1/17 chemoattraction. Thus, the expression of CXCL9 and CXCL10, common chemoattractants for CXCR3-positive Th1 and Th17 cells, is triggered in a biglycan-TLR4/TRIF-dependent manner. By contrast, biglycan induces CCL20 chemokine production, responsible for CCR6-positive Th17 cell recruitment, in a TLR2/4/MyD88-dependent manner. Importantly, at the onset of diabetes mellitus and lupus nephritis we provide evidence for biglycan-dependent recruitment of Th1 and Th17 cells, IFNγ and IL-17 production, and development of albuminuria in mice lacking or overexpressing soluble biglycan. Furthermore, by genetic ablation of Cxcl10 we showed in vivo involvement of this chemokine in biglycan-dependent recruitment of Th1 and Th17 cells into the kidney. Finally, a positive correlation of biglycan and CXCL10/CXCL9 levels was detected in plasma from patients with diabetic nephropathy and lupus nephritis. Taken together, we identified biglycan as a novel trigger of Th1 and Th17 cell recruitment into the kidney and we postulate that interfering with biglycan/TLR/TRIF/MyD88-signaling might provide novel therapeutic avenues for renal fibrosis. Copyright © 2017 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

  18. Th-1, Th-2 Cytokines Profile among Madurella mycetomatis Eumycetoma Patients.

    Science.gov (United States)

    Nasr, Amre; Abushouk, Amir; Hamza, Anhar; Siddig, Emmanuel; Fahal, Ahmed H

    2016-07-01

    Eumycetoma is a progressive and destructive chronic granulomatous subcutaneous inflammatory disease caused by certain fungi, the most common being Madurella mycetomatis. The host defence mechanisms against fungi usually range from an early non-specific immune response to activation and induction of specific adaptive immune responses by the production of Th-1 and Th-2 cytokines. The aim of this study is to determine the levels of Th-1 and Th-2 cytokines in patients infected with Madurella mycetomatis, and the association between their levels and disease prognosis. This is a descriptive cross-sectional study conducted at the Mycetoma Research Centre, University of Khartoum, Sudan, where 70 patients with confirmed M. mycetomatis eumycetoma were enrolled; 35 with, and 35 without surgical excision. 70 healthy individuals from mycetoma endemic areas were selected as controls. The levels of serum cytokines were determined by cytometric bead array technique. Significantly higher levels of the Th-1 cytokines (IFN-γ, TNF-α, IL-1β and IL-2) were recorded in patients treated with surgical excision, compared to those treated without surgical excision. In contrast, the Th-2 cytokines (IL-4, IL-5, IL-6 and IL-10) were significantly lower in patients treated with surgical excision compared to those treated without surgical excision. In conclusion, the results of this study suggest that cell-mediated immunity can have a role to play in the pathogenesis of eumycetoma.

  19. A Study of Fifth Graders' Environmental Learning Outcomes in Taipei

    Science.gov (United States)

    Lai, Ching-San

    2018-01-01

    Environmental education has recently received much more attention than before among elementary school students' science learning in Taiwan. The major purpose of this study is to explore the learning outcomes on environmental education for 5th graders in Taipei. A quasi-experimental design with a single group was used in this study. Students in the…

  20. 7th International Conference on Robotics in Education (RiE)

    CERN Document Server

    Lepuschitz, Wilfried; Koppensteiner, Gottfried; Balogh, Richard

    2017-01-01

    This proceedings volume showcases the latest achievements in research and development in Educational Robotics presented at the 7th International Conference on Robotics in Education (RiE) held in Vienna, Austria, during April 14-15, 2016. The book offers a range of methodologies for teaching robotics and presents various educational robotics curricula. It includes dedicated chapters for the design and analysis of learning environments as well as evaluation means for measuring the impact of robotics on the students’ learning success. Moreover, the book presents interesting programming approaches as well as new applications, the latest tools, systems and components for using robotics. The presented applications cover the whole educative range, from elementary school to high school, college, university and beyond, for continuing education and possibly outreach and workforce development. The book provides a framework involving two complementary kinds of contributions: on the one hand on technical aspects and on ...

  1. Experience-based teaching of acute medicine for extra motivated medical students and young physicians – 4th Emergency Medicine Course and 6th AKUTNĚ.CZ Congress

    Directory of Open Access Journals (Sweden)

    Petr Štourač

    2014-12-01

    Full Text Available Faculty of Medicine of the Masaryk University (MU, and especially its departments focusing on acute medicine, make an active effort to find and to support extra motivated students by organising courses and congresses with simulation-based learning sessions for them. 4th Emergency Medicine Course (EMC and 6th AKUTNĚ.CZ Congress were organised during 2014. EMC was held during a weekend in mid-April for 80 medical students. The congress was held on 22nd November 2014. A group of more than 700 enthusiastic professionals including physicians, nursing staff and medical students interested in acute medicine met again in Brno at the University Campus Bohunice. We also report the evaluation of effectiveness of different types of sessions, as well as its influence on practical skills and the fixation of memory footprint. The website AKUTNĚ.CZ (www.akutne.cz is freely accessible, and anyone can find and watch all the videos and presentations there.

  2. A Conceptual Framework for Ambient Learning Displays

    NARCIS (Netherlands)

    Börner, Dirk; Kalz, Marco; Specht, Marcus

    2011-01-01

    Börner, D., Kalz, M., & Specht, M. (2010, 29 November-3 December). A Conceptual Framework for Ambient Learning Displays. Poster presented at the Work-in-Progress Poster and Invited Young Researcher Symposium of the 18th International Conference on Computers in Education, Putrajaya, Malaysia:

  3. Proceedings of the 26th International Cryogenic Engineering Conference - International Cryogenic Material Conference 2016

    Science.gov (United States)

    Datta, T. S.; Sharma, R. G.; Kar, S.

    2017-02-01

    International Conference ICEC 26 - ICMC 2016 was organized at New Delhi, India during March 7-11, 2016. Previous conference ICEC25-ICMC 2014 was held at the University of Twente, The Netherlands in July 2014. Next Conference ICEC 27- ICMC 2018 will be held at Oxford, UK during September 3-7, 2018 1. Introduction This is a biennial international conference on cryogenic engineering and cryogenics materials organized by the International Cryogenic Engineering Committee and the International Cryogenic Material Committee. For some years, the host country has been alternating between Europe and Asia. The present conference was held at the Manekshaw Convention Centre, New Delhi, India during March 7-11, 2016 and hosted jointly by the Indian Cryogenics Council (ICC) and the Inter-University Accelerator Centre (IUAC), New Delhi. Put all together as many as 547 persons participated in the conference. Out of these 218 were foreign delegates coming from 25 countries and the rest from India. 2. Inaugural Session & Course Lectures The pre conference short course lectures on “Cryocoolers” and “Superconducting Materials for Power Applications” were organized on 7th March. Cryocooler course was given jointly by Dr. Chao Wang from M/s. Cryomech, USA and Prof. Milind Atrey from IIT Bombay, India. The Course on Superconducting Materials was given by Prof. Venkat Selvamanickam from the University of Houston, USA. The conference was inaugurated in the morning of March 8th in a typical Indian tradition and in the presence of the Chief Guest, Dr. R Chidambaram (Principle Scientific Adviser to Govt. of India), Guest of Honour, Prof. H Devaraj (Vice Chairman University Grant Commission), Prof Marcel ter Brake ( Chair, ICEC Board), Prof. Wilfried Goldacker (Chair, ICMC board), Dr. D Kanjilal (Director IUAC), Dr R K Bhandari, (President, Indian Cryogenic Council ). Dr. T S Datta, Chair Local Organizing Committee coordinated the proceedings of the inaugural function. 3. Technical

  4. TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression.

    Science.gov (United States)

    Liu, Hou-Pu; Cao, Anthony T; Feng, Ting; Li, Qingjie; Zhang, Wenbo; Yao, Suxia; Dann, Sara M; Elson, Charles O; Cong, Yingzi

    2015-04-01

    Differentiated CD4(+) T cells preserve plasticity under various conditions. However, the stability of Th1 cells is unclear, as is whether Th1 cells can convert into Th17 cells and thereby contribute to the generation of IFN-γ(+) IL-17(+) CD4(+) T cells, the number of which correlates with severity of colitis. We investigated whether IFN-γ(+) Th1 cells can convert into Th17 cells under intestinal inflammation and the mechanisms involved. IFN-γ(Thy1.1+) Th1 cells were generated by culturing naïve CD4(+) T cells from IFN-γ(Thy1.1) CBir1 TCR-Tg reporter mice, whose TCR is specific for an immunodominant microbiota antigen, CBir1 flagellin, under Th1 polarizing conditions. IFN-γ(Thy1.1+) Th1 cells induced colitis in Rag(-/-) mice after adoptive transfer and converted into IL-17(+) Th17, but not Foxp3(+) Treg cells in the inflamed intestines. TGF-β and IL-6, but not IL-1β and IL-23, regulated Th1 conversion into Th17 cells. TGF-β induction of transcriptional factor Runx1 is crucial for the conversion, since silencing Runx1 by siRNA inhibited Th1 conversion into Th17 cells. Furthermore, TGF-β enhanced histone H3K9 acetylation but inhibited H3K9 trimethylation of Runx1- and ROR-γt-binding sites on il-17 or rorc gene in Th1 cells. We conclude that Th1 cells convert into Th17 cells under inflammatory conditions in intestines, which is possibly mediated by TGF-β induction of Runx1. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Learning Management Platform for CyberCIEGE

    Science.gov (United States)

    2011-12-01

    CLE is a platform that allows academic and research collaboration and it is built on open pedagogy and open standard [16]. In those situations...C. Irvine, “Active learning with the CyberCIEGE video game,” in Proceedings of the 4th Conference on Cyber Security Experimentation and Test, 2011

  6. Electronic Dictionary as a Tool for Integration of Additional Learning Content

    Directory of Open Access Journals (Sweden)

    Stefka Kovacheva

    2015-12-01

    Full Text Available Electronic Dictionary as a Tool for Integration of Additional Learning Content This article discusses electronic dictionary as an element of the „Bulgarian cultural and historical heritage under the protection of UNESCO” database developed in IMI (BAS, that will be used to integrate additional learning content. The electronic dictionary is described as an easily accessible book of reference, offering information to the shape, meaning, usage and the origin of words in connection to the cultural-historical heritage sites in Bulgaria, protected by UNESCO. The dictionary targets 9–11 year old students from Bulgarian schools, who study the subjects “Man and Society” in 4th grade and “History and Civilization” in 5th grade.

  7. Associative learning for a robot intelligence

    CERN Document Server

    Andreae, John H

    1998-01-01

    The explanation of brain functioning in terms of the association of ideas has been popular since the 17th century. Recently, however, the process of association has been dismissed as computationally inadequate by prominent cognitive scientists. In this book, a sharper definition of the term "association" is used to revive the process by showing that associative learning can indeed be computationally powerful. Within an appropriate organization, associative learning can be embodied in a robot to realize a human-like intelligence, which sets its own goals, exhibits unique unformalizable behaviou

  8. Direct Measurement of Initial 230TH/ 232TH Ratios in Central Texas Speleothems for More Accurate Age Determination

    Science.gov (United States)

    Wortham, B. E.; Banner, J. L.; James, E.; Loewy, S. L.

    2013-12-01

    Speleothems, calcite deposits in caves, preserve a record of climate in their growth rate, isotope ratios and trace element concentrations. These variables must be tied to precise ages to produce pre-instrumental records of climate. The 238U-234U- 230Th disequilibrium method of dating can yield precise ages if the amount of 230Th from the decay of radiogenic 238U can be constrained. 230Th in a speleothem calcite growth layer has two potential sources - 1) decay of radioactive 238U since the time of growth of the calcite layer; and 2) initial detrital 230Th, incorporated along with detrital 232Th, into the calcite layer at the time it grew. Although the calcite lattice does not typically incorporate Th, samples can contain impurities with relatively high Th contents. Initial 230Th/232Th is commonly estimated by assuming a source with bulk-Earth U/Th values in a state of secular equilibrium in the 238U-decay chain. The uncertainty in this 230Th/232Th estimate is also assumed, typically at +/-100%. Both assumptions contribute to uncertainty in ages determined for young speleothems. If the amount of initial detrital 230Th can be better quantified for samples or sites, then U-series ages will have smaller uncertainties and more precisely define the time series of climate proxies. This study determined the initial 230Th/232Th of modern calcite to provide more precise dates for central Texas speleothems. Calcite was grown on glass-plate substrates placed under active drips in central Texas caves. The 230Th/232Th of this modern calcite was determined using thermal ionization mass spectrometry. Results show that: 1) initial 230Th/232Th ratios can be accurately determined in these young samples and 2) measuring 230Th/232Th reduces the uncertainties in previously-determined ages on stalagmites from under the same drips. For example, measured initial 230Th/232Th in calcite collected on substrates from different locations in the cave at Westcave Preserve are 15.3 × 0.67 ppm

  9. Aberrant Production of Th1/Th2/Th17-Related Cytokines in Serum of C57BL/6 Mice after Short-Term Formaldehyde Exposure

    Directory of Open Access Journals (Sweden)

    Haiyan Wei

    2014-09-01

    Full Text Available Previous studies have shown that formaldehyde (FA could cause immunotoxicity by changing the number of T lymphocytes and that cytokines play a pivotal role in the regulation of T lymphocytes. However, the previously used cytokine detection methods are difficult to use in the measurement of several cytokines in a small amount of sample for one test. Therefore, the cytometric bead array (CBA technique was used. CBA showed better analytical efficiency and sensitivity than the previous methods. C57BL/6 mice were exposed to the control (normal saline, low FA concentration (0.5 mg/kg, and high FA concentration (2 mg/kg for 1 week or 1 month. The contents of cytokines, including Th1-related cytokines (IL-2, IFN-γ, and tumor necrosis factor, Th2-related cytokines (IL-4, IL-6, and IL-10, and Th17-related cytokines (IL-17A, were measured by using the BD FACS Canto II Flow Cytometer and analyzed by FCAP ArrayTM Software. Th1/Th2/Th17-related cytokines showed a slightly decreasing trend after low FA exposure. Conversely, a significantly increasing trend was found after high FA exposure. Th1/Th2/Th17-related cytokines all serve important functions in the immune reactions in mice after FA exposure.

  10. 26 CFR 1.401(a)(26)-7 - Testing methods.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Testing methods. 1.401(a)(26)-7 Section 1.401(a... (CONTINUED) INCOME TAXES Pension, Profit-Sharing, Stock Bonus Plans, Etc. § 1.401(a)(26)-7 Testing methods... the rules in § 1.401(a)(26)-5. (b) Simplified testing method. A plan is treated as satisfying the...

  11. I WHATSAPP AN IGUANA: AN ATTEMPT TO APPLY UBIQUITOUS LEARNING

    OpenAIRE

    Dwi Haryanti

    2017-01-01

    This paper aims at presenting how Whatsapp provides alternative method to enhance writing skills on personal letter for senior high school student. This method Whatsapps inspired by the concept called ubiquitous learning (U-Learning), which means ―learning supported by ICT resources held anytime, anywhere and fits the context of the learner‖ (de Sousa Monteiro et al., 2014). Participants were 40 11-th grade students in one class in Cirebon High School. A short story in the form of personal le...

  12. In situ detrital zircon (U-Th)/He thermochronology

    Science.gov (United States)

    Tripathy, A.; Monteleone, B. D.; van Soest, M. C.; Hodges, K.; Hourigan, J. K.

    2010-12-01

    Detrital studies of both sand and rock are relevant to many problems, ranging from the climate and tectonics feedback debate to the long-term record of orogenic evolution. When applying the conventional (U-Th)/He technique to such studies, two important issues arise. Often, only euhedral grains are permissible for analysis in order to make simple geometric corrections for α-recoil. In detrital samples, this is problematic because euhedral grains can be scarce due to mechanical abrasion during transport, and potentially introduce bias in favour of more proximally sourced grains. Second, inherent to detrital studies is the need to date many grains (>100) per sample to ensure a representative sampling of the sediment source region, thus making robust conventional detrital studies both expensive and time-consuming. UV laser microprobes can improve this by permitting careful targeting of the grain interior away from the α-ejection zone, rendering the α-recoil correction unnecessary, thus eliminating bias toward euhedral grains. In the Noble Gas, Geochemistry, and Geochronology Laboratory at ASU, apatite and zircon have been successfully dated using in situ methods. For this study, the conventional and in situ techniques are compared by dating zircons from a modern river sand that drains a small catchment in the Mesozoic-Cenozoic Ladakh Batholith in NW India. This sample has a simple provenance, which allows us to demonstrate the robustness of the in situ method. Moreover, different microbeam techniques will be explored to establish the most efficient approach to obtain accurate and precise U-Th concentrations using synrock, which is our powdered, homogenized, and reconstituted zircon-rock standard. Without this, such in situ U-Th data would be difficult to obtain. 117 zircons were dated using the conventional (U-Th)/He method, revealing dates ranging from 9.70±0.35 to 106.6±3.5 Ma (2σ) with the major mode at 26 Ma. For comparison, 44 grains were dated using the in

  13. Determination of Sc and Th in ScI3-NaI-ThI4 sample

    International Nuclear Information System (INIS)

    Yuan Hui; Yang Zhihong

    1999-01-01

    Determination of Sc and Th in ScI 3 -NaI-ThI 4 sample is studied by X-ray fluorescence and complexometry. The effect of working condition of Sc on X-ray fluorescence spectrometer and different sample-making method on the determination of Sc and Th are studied experimentally. The X-ray fluorescence analysis of determination of Sc and Th is developed by polyester film sample-making technique, the measuring precision of Sc and Th is better than 4%. The effect of acidity and temperature on the determining end point of titration is obvious. The results of different complexometric methods are compared. The precision of Sc and Th is less than 2% by comlexometry, it is fit for the routine analysis of ScI 3 -NaI-ThI 4 sample

  14. Determination of 230Th/232Th and correct methods by High Resolution Inductively Coupled Plasma Mass Spectrometry

    International Nuclear Information System (INIS)

    Xie Shengkai; Guo Dongfa; Tan Jing; Zhang Yanhui; Huang Qiuhong; Gao Aiguo

    2013-01-01

    It is very important for the rapid and reliable determination of 230 Th/ 232 Th in the thorium-230 dating. A method of measuring 230 Th/ 232 Th in natural samples by high resolution inductively coupled plasma mass spectrometer (HR-ICP-MS) was developed on the base of our former work. The precise and accurate of natural 230 Th in geology samples is challenging, as the peak tailing to the high intensity of neighboring peak at 232 Th and the mass discrimination of the instrument. The peak tailing of 238 U to 236 U was used to decrease the peak tailing effect of 232 Th to 230 Th. The mass discrimination factor K between ture and measured isotope ratio was calculated after measuring different 230 Th/ 232 Th ratio solutions. Lab used standard samples was digested in mixed acids of HN0 3 -HF-HCI-HCl0 4 , and separated by the Bio-rad AG 1 × 8 Cl - resin. The measurement method of blank-standard-blank-sample procession was used to determinate the 230 Th/ 232 Th. The measured result of 230 Th/ 232 Th was at (7.29 ± 0.34) × 10 -6 , which agreed with the reference value of (7.33 ± 0.17) × 10 -6 . (authors)

  15. Methylmercury chloride induces learning deficits in prenatally treated rats

    Energy Technology Data Exchange (ETDEWEB)

    Muesch, H.R.; Bornhausen, M.; Kriegel, H.; Greim, H.

    1978-01-01

    Methylmercury chloride (MMC) was given to pregnant rats on the 6th, 7th, 8th, and 9th day after conception in doses of 0.05 and 2.0 mg/kg/day. The female offspring of these animals were tested 90 days after birth for learning ability using operant conditioning procedures. The rats were kept at 90% of their normal body weight and trained in a lever-box to press a bar in order to obtain a food pellet. Significant differences in the acquisition speed became apparent when the ratio of bar presses to reward was increased in a classical contingency of differential reinforcement of high rates even at MMC-doses of 4 x 0.05 mg/kg. These differences were not found in the general motility level nor in motor coordination.

  16. Overview of the 9th International Conference on Hydrodynamics

    Science.gov (United States)

    Lu, Dong-qiang

    2010-10-01

    The 9th International Conference on Hydrodynamics (ICHD), held in Shanghai, China from 11 to 15 October, 2010, was briefly reviewed. More than 240 delegates from 23 countries and regions attended this Conference, at which three plenary lectures, two keynote lectures and more than 160 papers were delivered. A special symposium on hydrodynamics in honor of Prof. You-sheng He was jointly organized in this ICHD. The printed proceedings, edited by Y. S. Wu, S. Q. Dai, H. Liu et al. and published by China Ocean Press, collect 172 technical papers contributed from 26 countries and regions. The electronic proceedings are distributed by the Elsevier at the ScienceDirect website as "Journal of Hydrodynamics, 2010, Vol. 22, No. 5 (Supplement)".

  17. The effect of multiple intelligence-based learning towards students’ concept mastery and interest in learning matter

    Science.gov (United States)

    Pratiwi, W. N.; Rochintaniawati, D.; Agustin, R. R.

    2018-05-01

    This research was focused on investigating the effect of multiple intelligence -based learning as a learning approach towards students’ concept mastery and interest in learning matter. The one-group pre-test - post-test design was used in this research towards a sample which was according to the suitable situation of the research sample, n = 13 students of the 7th grade in a private school in Bandar Seri Begawan. The students’ concept mastery was measured using achievement test and given at the pre-test and post-test, meanwhile the students’ interest level was measured using a Likert Scale for interest. Based on the analysis of the data, the result shows that the normalized gain was .61, which was considered as a medium improvement. in other words, students’ concept mastery in matter increased after being taught using multiple intelligence-based learning. The Likert scale of interest shows that most students have a high interest in learning matter after being taught by multiple intelligence-based learning. Therefore, it is concluded that multiple intelligence – based learning helped in improving students’ concept mastery and gain students’ interest in learning matter.

  18. STEM learning on electricity using arduino-phet based experiment to improve 8th grade students’ STEM literacy

    Science.gov (United States)

    Prima, E. C.; Oktaviani, T. D.; Sholihin, H.

    2018-05-01

    Technology is the application of scientific knowledge for practical purposes, especially in industry. One way to support the development of the technology is by integrating the use of technology and build the technology with the learning process in the form of STEM (science, technology, engineering, mathematics) Learning approach. Applying STEM Learning could improve Students’ STEM Literacy. The learning approach is applied in every aspect of Learning including the application of STEM Learning in the lesson plan and worksheet. The method used in this research is weak experimental method. One group class (N=15) is taken and learn using STEM Learning approach. The topic choosen is the electricity topic which is separated into electrical circuit and parameters. The learning process is separated into 3 meetings. 15 Students are given a STEM Literacy test item before and after the lesson. The result of the normalized gain shows there are improvement in students’ STEM Literacy by 0.16 categorieed as low improvement. The most higher improvement is the students’ technology literacy, because students learn using the same technology in every meeting. This factor influences students’ technology literacy so the result is higher than another.

  19. A Conceptual Framework for Ambient Learning Displays

    NARCIS (Netherlands)

    Börner, Dirk; Kalz, Marco; Specht, Marcus

    2010-01-01

    Börner, D., Kalz, M., & Specht, M. (2010). A Conceptual Framework for Ambient Learning Displays. In B. Chang, T. Hirashima, & H. Ogata (Eds.), Joint Proceedings of the Work-in-Progress Poster and Invited Young Researcher Symposium for the 18th International Conference on Computers in Education (pp.

  20. Teaching 5th grade science for aesthetic understanding

    Science.gov (United States)

    Girod, Mark A.

    Many scientists speak with great zeal about the role of aesthetics and beauty in their science and inquiry. Few systematic efforts have been made to teach science in ways that appeal directly to aesthetics and this research is designed to do just that. Drawing from the aesthetic theory of Dewey, I describe an analytic lens called learning for aesthetic understanding that finds power in the degree to which our perceptions of the world are transformed, our interests and enthusiasm piqued, and our actions changed as we seek further experiences in the world. This learning theory is contrasted against two other current and popular theories of science learning, that of learning for conceptual understanding via conceptual change theory and learning for a language-oriented or discourse-based understanding. After a lengthy articulation of the pedagogical strategies used to teach for aesthetic understanding the research is described in which comparisons are drawn between students in two 5th grade classrooms---one taught for the goal of conceptual understanding and the other taught for the goal of aesthetic understanding. Results of this comparison show that more students in the treatment classroom had aesthetic experiences with science ideas and came to an aesthetic understanding when studying weather, erosion, and structure of matter than students in the control group. Also statistically significant effects are shown on measures of interest, affect, and efficacy for students in the treatment class. On measures of conceptual understanding it appears that treatment class students learned more and forgot less over time than control class students. The effect of the treatment does not generally depend on gender, ethnicity, or prior achievement except in students' identity beliefs about themselves as science learners. In this case, a significant interaction for treatment class females on science identity beliefs did occur. A discussion of these results as well as elaboration and

  1. Building mathematics cellular phone learning communities

    Directory of Open Access Journals (Sweden)

    Wajeeh M. Daher

    2011-04-01

    Full Text Available Researchers emphasize the importance of maintaining learning communities and environments. This article describes the building and nourishment of a learning community, one comprised of middle school students who learned mathematics out-of-class using the cellular phone. The building of the learning community was led by three third year pre-service teachers majoring in mathematics and computers. The pre-service teachers selected thirty 8th grade students to learn mathematics with the cellular phone and be part of a learning community experimenting with this learning. To analyze the building and development stages of the cellular phone learning community, two models of community building stages were used; first the team development model developed by Tuckman (1965, second the life cycle model of a virtual learning community developed by Garber (2004. The research findings indicate that a learning community which is centered on a new technology has five 'life' phases of development: Pre-birth, birth, formation, performing, and maturity. Further, the research finding indicate that the norms that were encouraged by the preservice teachers who initiated the cellular phone learning community resulted in a community which developed, nourished and matured to be similar to a community of experienced applied mathematicians who use mathematical formulae to study everyday phenomena.

  2. 7th IEEE International Conference Intelligent Systems

    CERN Document Server

    Atanassov, KT; Doukovska, L; Hadjiski, M; Jotsov, V; Kacprzyk, J; Kasabov, N; Sotirov, S; Szmidt, E; Zadrożny, S; Filev, D; Jabłkowski, J; Kacprzyk, J; Krawczak, M; Popchev, I; Rutkowski, L; Sgurev, V; Sotirova, E; Szynkarczyk, P

    2015-01-01

    This two volume set of books constitutes the proceedings of the 2014  7th IEEE International Conference Intelligent Systems (IS), or IEEE IS’2014 for short, held on September 24‐26, 2014 in Warsaw, Poland. Moreover, it contains some selected papers from the collocated IWIFSGN'2014-Thirteenth International Workshop on Intuitionistic Fuzzy Sets and Generalized Nets.The conference was organized by the Systems Research Institute, Polish Academy of Sciences, Department IV of Engineering Sciences, Polish Academy of Sciences, and Industrial Institute of Automation and Measurements - PIAP.The papers included in the two proceedings volumes have been subject to a thorough review process by three highly qualified peer reviewers.Comments and suggestions from them have considerable helped improve the quality of the papers but also the division of the volumes into parts, and assignment of the papers to the best suited parts.  

  3. A cross-sectional study of learning styles among continuing medical education participants.

    Science.gov (United States)

    Collins, C Scott; Nanda, Sanjeev; Palmer, Brian A; Mohabbat, Arya B; Schleck, Cathy D; Mandrekar, Jayawant N; Mahapatra, Saswati; Beckman, Thomas J; Wittich, Christopher M

    2018-04-27

    Experiential learning has been suggested as a framework for planning continuing medical education (CME). We aimed to (1) determine participants' learning styles at traditional CME courses and (2) explore associations between learning styles and participant characteristics. Cross-sectional study of all participants (n = 393) at two Mayo Clinic CME courses who completed the Kolb Learning Style Inventory and provided demographic data. A total of 393 participants returned 241 surveys (response rate, 61.3%). Among the 143 participants (36.4%) who supplied complete demographic and Kolb data, Kolb learning styles included diverging (45; 31.5%), assimilating (56; 39.2%), converging (8; 5.6%), and accommodating (34; 23.8%). Associations existed between learning style and gender (p = 0.02). For most men, learning styles were diverging (23 of 63; 36.5%) and assimilating (30 of 63; 47.6%); for most women, diverging (22 of 80; 27.5%), assimilating (26 of 80; 32.5%), and accommodating (26 of 80; 32.5%). Internal medicine and psychiatry CME participants had diverse learning styles. Female participants had more variation in their learning styles than men. Teaching techniques must vary to appeal to all learners. The experiential learning theory sequentially moves a learner from Why? to What? to How? to If? to accommodate learning styles.

  4. Impact of tablet computers and eBooks on learning practices of law students

    NARCIS (Netherlands)

    Kalz, Marco; Specht, Marcus; Van Oosterzee, Michiel

    2012-01-01

    Kalz, M., Specht, M., & Van Oosterzee, M. (2012). Impact of tablet computers and eBooks on learning practices of law students. In M. Specht, J. Multisilta, & M. Sharples (Eds.), Proceedings of the 11th World Conference on Mobile and Contextual Learning 2012 (pp. 203-208). October, 16-18, 2012,

  5. Fasciola hepatica reinfection potentiates a mixed Th1/Th2/Th17/Treg response and correlates with the clinical phenotypes of anemia

    Science.gov (United States)

    Perez-Crespo, Ignacio; Chillón-Marinas, Carlos; Khoubbane, Messaoud; Quesada, Carla; Reguera-Gomez, Marta; Mas-Coma, Santiago; Fresno, Manuel; Gironès, Núria

    2017-01-01

    Background Fascioliasis is a severe zoonotic disease of worldwide extension caused by liver flukes. In human fascioliasis hyperendemic areas, reinfection and chronicity are the norm and anemia is the main sign. Herein, the profile of the Th1/Th2/Th17/Treg expression levels is analyzed after reinfection, correlating them with their corresponding hematological biomarkers of morbidity. Methodology/Principal findings The experimental design reproduces the usual reinfection/chronicity conditions in human fascioliasis endemic areas and included Fasciola hepatica primo-infected Wistar rats (PI) and rats reinfected at 8 weeks (R8), and at 12 weeks (R12), and negative control rats. In a cross-sectional study, the expression of the genes associated with Th1 (Ifng, Il12a, Il12b, Nos2), Th2 (Il4, Arg1), Treg (Foxp3, Il10, Tgfb, Ebi3), and Th17 (Il17) in the spleen and thymus was analyzed. After 20 weeks of primary infection, PI did not present significant changes in the expression of those genes when compared to non-infected rats (NI), but an increase of Il4, Arg1 and Ifng mRNA in the spleen was observed in R12, suggesting the existence of an active mixed Th1/Th2 systemic immune response in reinfection. Foxp3, Il10, Tgfb and Ebi3 levels increased in the spleen in R12 when compared to NI and PI, indicating that the Treg gene expression levels are potentiated in chronic phase reinfection. Il17 gene expression levels in R12 in the spleen increased when compared to NI, PI and R8. Gene expression levels of Il10 in the thymus increased when compared to NI and PI in R12. Ifng expression levels in the thymus increased in all reinfected rats, but not in PI. The clinical phenotype was determined by the fluke burden, the rat body weight and the hemogram. Multivariate mathematical models were built to describe the Th1/Th2/Th17/Treg expression levels and the clinical phenotype. In reinfection, two phenotypic patterns were detected: i) one which includes only increased splenic Ifng

  6. Knowing Obama: How High School Students of Color Learn about the 44th President

    Science.gov (United States)

    Smith, William

    2016-01-01

    Drawing from a theory of racial literacy and literature on the post-racial phenomenon after the 2008 election, this case study examines how high school students of color have learned about Barack Obama as a racial and political figure. Findings suggest that schools can be unfriendly spaces for learning about these topics, with history and social…

  7. Can a Multimedia Tool Help Students' Learning Performance in ...

    African Journals Online (AJOL)

    Hennie

    2015-11-25

    Nov 25, 2015 ... During the research process, an experimental design with two groups, TCbio (n = 22) and Mbio (n = 26), were used. The results of .... as well as their views towards learning approaches. Based on this ..... image, number, logic, rhythm, colour and spatial .... /learning process can be better supported via multi-.

  8. Proton-induced fission of actinides at energies 26.5 and 62.9 MeV--Theoretical interpretation

    International Nuclear Information System (INIS)

    Demetriou, P.; Keutgen, Th.; Prieels, R.; El Masri, Y.

    2011-01-01

    Fission properties of proton-induced fission on 232 Th, 237 Np, 238 U, 239 Pu and 241 Am targets, measured at the Louvain-la-Neuve cyclotron facility at proton energies of 26.5 and 62.9 MeV, are compared with the predictions of the state-of-the-art nuclear reaction code TALYS. The sensitivity of the calculations to the input parameters of the code and possible improvements are discussed.

  9. The Effect of Context-Based Chemical Equilibrium on Grade 11 Students' Learning, Motivation and Constructivist Learning Environment

    Science.gov (United States)

    ilhan, Nail; Yildirim, Ali; Yilmaz, Sibel Sadi

    2016-01-01

    In recent years, many countries have adopted a context-based approach for designing science curricula for education at all levels. The aim of this study was to determine the effectiveness of a Context-Based Chemistry Course (CBCC) as compared with traditional/existing instruction, on 11th grade students' learning about chemical equilibrium,…

  10. Association between Th1/Th2 immune imbalance and obesity in women with or without polycystic ovary syndrome.

    Science.gov (United States)

    Gong, Ping; Shi, Bingwei; Wang, Juan; Cao, Peixia; Diao, Zhenyu; Wang, Yuji; Hu, Yali; Li, Shuping

    2018-02-15

    This study aimed to investigate the Th1/Th2 cells in peripheral blood of PCOS patients, and assess the potential correlation between Th1/Th2 imbalance and obesity. Thirty-nine PCOS patients and 23 age-matched controls were enrolled. The PBMCs were obtained before pharmacological intervention in women with or without PCOS. The profiles of Th1 (IFN-γ) and Th2 (IL-4) cytokines of CD3 + CD - T lymphocyte subsets were analyzed by flow cytometry. Plasma sex hormones including E 2 , T, FSH, LH, and FINS, FPG were measured, together with BMI, WC, LH/FSH, E 2 /T and HOMA-IR index being calculated. Association between Th1/Th2 imbalance and BMI, WC were evaluated. The proportion of Th1 cells and Th1/Th2 ratio were significantly higher in PCOS patients than those in controls, accompanied by elevated T, LH, LH/FSH, FINS, HOMA-IR index and reduced E 2 /T. The Th1/Th2 ratio was increased when BMI and WC were enhanced in PCOS. Moreover, the significant difference of Th1/Th2 ratio was observed between WC subgroups of PCOS. It is concluded that Th1 type immunity is predominant in systemic immunization of PCOS patients. Th1/Th2 immune imbalance is connected with obesity, especially abdominal obesity, and may be one of the underlying mechanism for the pathogenesis of PCOS.

  11. General Video Game AI: Learning from Screen Capture

    OpenAIRE

    Kunanusont, Kamolwan; Lucas, Simon M.; Perez-Liebana, Diego

    2017-01-01

    General Video Game Artificial Intelligence is a general game playing framework for Artificial General Intelligence research in the video-games domain. In this paper, we propose for the first time a screen capture learning agent for General Video Game AI framework. A Deep Q-Network algorithm was applied and improved to develop an agent capable of learning to play different games in the framework. After testing this algorithm using various games of different categories and difficulty levels, th...

  12. Current and Future Trends in Game-Based Learning

    Directory of Open Access Journals (Sweden)

    Carlos Vaz de Carvalho

    2014-05-01

    Full Text Available The first number of the second volume of the EAI Transactions on Serious Games focuses on the results presented on the European Conference on Game-Based Learning. This event, already on the 8th edition, has set standards in terms of presentation of research and practice and in the pointing out of new and future trends in the development of Game-Based Learning. As such, we are quite thrilled to be able to report them here.

  13. Book of abstracts: International Conference on Smart Energy Systems and 4th Generation District Heating

    DEFF Research Database (Denmark)

    , which takes a sole focus on the electricity sector, the smart energy systems approach includes the entire energy system in its identification of suitable energy infrastructure designs and operation strategies. Focusing solely on the smart electricity grid often leads to the definition of transmission......It is a great pleasure to welcome you to the first International Conference on Smart Energy Systems and 4th Generation District Heating at Aalborg University, Copenhagen Campus on 25-26 August 2015. The conference is organised by the 4DH Strategic Research Centre in collaboration with Aalborg...... University and offers more than 70 presentations in 3 parallel sessions with more than 180 participants from 25 countries around the world. The aim is to present and discuss scientific findings and industrial experiences related to the development of Smart Energy Systems and future 4th Generation District...

  14. Situation Creator: A Pedagogical Agent Creating Learning Opportunities

    NARCIS (Netherlands)

    Miao, Yongwu; Hoppe, Ulrich; Pinkwart, Niels

    2007-01-01

    Miao, Y., Hoppe, H. U., & Pinkwart, N. (2007). Situation Creator: A Pedagogical Agent Creating Learning Opportunities. In R. Luckin, K. Koedinger & J. Greer (Eds.), Proceedings of the 13th International Conference on Artificial Intelligence in Education (pp. 614-617). Amsterdam, The Netherlands: IOS

  15. The Factor Structure of Coordination Abilities Development in 5th-7th Grade Boys

    Directory of Open Access Journals (Sweden)

    В. В. Приходько

    2017-12-01

    Full Text Available The objective is to determine the structure of coordination abilities development in 5th-7th grade boys. Materials and methods. The participants in the study were boys of the 5th grade (n=21, 6th grade (n=20, and 7th grade (n=19. The paper used analysis and generalization of the scientific and methodological literature data, general scientific methods of theoretical level, namely: analogy, analysis, synthesis, abstracting, induction, as well as general scientific methods of empirical level: observation, testing, experiment. To evaluate of the motor preparedness, the results of motor tests, height and body weight were recorded. The materials of the study were processed in the statistical analysis program IBM SPSS 20. Factor analysis was carried out using a model of the principal components with the rotation method: Variamax with Kaiser normalization. Results. Analysis of the similarities shows that the most informative in the structure of the 5th grade boys’ motor preparedness are Test 9 “Static Equilibrium Evaluation by E. Ya. Bondarevsky’s Method” (,999, Test 2 “Standing Long Jump (cm” (,998, Test 10 “Dynamic Equilibrium Evaluation by Bess Method” (,916; for the 6th grade boys such are Test 9 “Static Equilibrium Evaluation by E. Ya. Bondarevsky’s Method” (1.0, Test 2 “Standing Long Jump (cm” (,999, Test 5 “Sit-Up for 30 sec.” (,968, Test 10 “Dynamic Equilibrium Evaluation by Bess Method” (,918; for the 7th grade boys such are Test 2 “Standing Long Jump (cm” (,994, Test 9 “Static Equilibrium Evaluation by E. Ya. Bondarevsky’s Method” (,987, Test 10 “Dynamic Equilibrium Evaluation by Bess Method” (,945. Conclusions. The most informative in the structure of 5th-7th grade boys’ coordination abilities is vestibular tolerance. For pedagogical control of 5th-7th grade boys’ motor preparedness the following can be recommended: Test 2 “Standing Long Jump (cm”, Test 9 “Static Equilibrium

  16. 19. srednjeevropska konferenca o informatiki in inteligentnih sistemih = 19th Central European Conference on Information and Intelligent Systems

    Directory of Open Access Journals (Sweden)

    Armand Faganel

    2008-12-01

    Full Text Available The aim of the paper is to present the 19th Central European Conference on Information and Intelligent Systems, CECIIS 2008, which took place between 24th and 26th September in Varaždin and was organised by the Faculty of Organisation and Informatics in Varaždin. The central theme of this year’s conference was e-government. During those 3 days, 250 participants could attend presentations of 90 scientific and professional works in 15 sections and 9 invited lectures on the newest trends in the area of information and communication technology management, information technologies, security of information systems, multimedia systems, strategic planning of information systems, education for information society. Two other parallel events were held within the international conference, namely the workshop ‘Activities towards ICT professionalism’ and a round table on the subject ‘Competences of ICT Professionals’. Experts in the field of human resources, leaders of information centres and managers of the leading Croatian companies participated in the latter.

  17. A real CDIO mechanical engineering project in 4th semester

    DEFF Research Database (Denmark)

    Lauritsen, Aage Birkkjær

    In the past 6 years at the mechanical engineering study at the Engineering College of Aarhus we have been practicing project work on 4th Semester in the design of energy technology systems. In my presentation, I will give a description of the project, and the thoughts behind; pedagogic......-6 students, and will partly support the general theory being taught in the courses, but will also provide students with skills in teamwork, project work and system building. The pedagogical considerations behind the development of the project are quite simply that students learn best through active work...

  18. Search as Learning (Dagstuhl Seminar 17092)

    OpenAIRE

    Collins-Thompson, Kevyn; Hansen, Preben; Hauff, Claudia

    2017-01-01

    This report describes the program and the results of Dagstuhl Seminar 17092 "Search as Learning", which brought together 26 researchers from diverse research backgrounds. The motivation for the seminar stems from the fact that modern Web search engines are largely engineered and optimized to fulfill lookup tasks instead of complex search tasks. The latter though are an essential component of information discovery and learning. The 3-day seminar started with four perspective talks, providing f...

  19. Chemistry to music: Discovering how Music-based Teaching affects academic achievement and student motivation in an 8th grade science class

    Science.gov (United States)

    McCammon, William Gavin Lodge, Jr.

    Teachers should have access to new and innovative tools in order to engage and motivate their students in the classroom. This is especially important as many students view school as an antiquated and dull environment - which they must seemingly suffer through to advance. School need not be a dreaded environment. The use of music as a tool for learning can be employed by any teacher to create an engaging and exciting atmosphere where students actively participate and learn to value their classroom experience. Through this study, a product and process was developed that is now available for any 8th grade science teacher interested in using music to enhance their content. In this study 8th grade students (n=41) in a public school classroom actively interacted with modern songs created to enhance the teaching of chemistry. Data were collected and analyzed in order to determine the effects that the music treatment had on student achievement and motivation, compared to a control group (n=35). Current literature provides a foundation for the benefits for music listening and training, but academic research in the area of using music as a tool for teaching content was noticeably absent. This study identifies a new area of research called "Music-based Teaching" which results in increases in motivation for 8th grade students learning chemistry. The unintended results of the study are additionally significant as the teacher conducting the treatment experienced newfound enthusiasm, passion, and excitement for her profession.

  20. Movement Coordination: Factor Structure of Development in 5th-7th Grade Girls

    Directory of Open Access Journals (Sweden)

    O. Ivashchenko

    2018-03-01

    Full Text Available The study objective is to determine the structure of coordination abilities development in 5th-7th grade girls. Materials and methods. The participants in the study were 5th grade girls (n = 20, 6th grade girls (n = 23, 7th grade girls (n = 19. The study used the following methods: analysis and collation of scientific and methodological literature, general scientific methods of theoretical level, such as analogy, analysis, synthesis, abstraction, induction, as well as general scientific methods of empirical level: observation, testing, experiment. To evaluate motor preparedness, the study recorded the results of motor tests, body height and weight. The IBM SPSS 20 statistical analysis software was used to process the study materials. A factor analysis was performed, for which the study used principal component analysis with the rotation method: Variamax with Kaiser Normalization. Results. The analysis of similarities shows that the most informative tests in the structure of motor preparedness of the 5th grade girls are the following: test 11 “Evaluation of the ability for vestibular (statokinetic stability. Running with turns” (.884, test 9 “Static equilibrium evaluation by E. Ya. Bondarevsky’s method” (.826, test 6 “Evaluation of the sense of movement speed in sprinting” (.824; of the 6th grade girls — test 11 “Evaluation of the ability for vestibular (statokinetic stability. Running with turns” (0.884, test 9 “Static equilibrium evaluation by E. Ya. Bondarevsky’s method” (.826, test 6 “Evaluation of the sense of movement speed in sprinting” (.824; of the 7th grade girls — test 8 “Evaluation of the ability to differentiate movement speed (reproduction accuracy of running speed at 90% intensity of maximum” (.902, test 11 “Evaluation of the ability for vestibular (statokinetic stability. Running with turns” (.900, test 1 “30 m running (s” (.869. Conclusions. In the structure of

  1. Valladolid, a Festival Town (17th-18th Centuries

    Directory of Open Access Journals (Sweden)

    Lourdes AMIGO VÁZQUEZ

    2017-11-01

    Full Text Available The festival was a great sociocultural event whose dimensions reached their maximum evolution in Early Modern Spain, especially in the 17th and 18th centuries and in its urban centres. This was the «festive society» par excellence, because of the frequency of the celebrations and the multiplicity of meanings, implications and consequences. Society and power, ultimately, were represented at the festival. In this context, the specific case of Valladolid demonstrates both its character as a germane model, applicable to any other town, and its uniqueness. Significantly, in the early 17th century it was once again the seat of the Court and yet even after being abandoned by Philip III in 1606, it continued to be one of the most important towns of Castile, the seat of the Royal Chancellery.

  2. Using the mixed media according to internet-based on the instructional multimedia for developing students' learning achievements in biology course on foundational cell issue of secondary students at the 10th grade level in Rangsit University demonstration school

    Science.gov (United States)

    Kangloan, Pichet; Chayaburakul, Kanokporn; Santiboon, Toansakul

    2018-01-01

    The aims of this research study were 1) to develop students' learning achievements in biology course on foundational cell issue, 2) to examine students' satisfactions of their learning activities through the mixed media according to internet-based multi-instruction in biology on foundational cell issue at the 10th grade level were used in the first semester in the academic year 2014, which a sample size of 17 students in Rangsit University Demonstration School with cluster random sampling was selected. Students' learning administrations were instructed with the 3-instructional lesson plans according to the 5-Step Ladder Learning Management Plan (LLMP) namely; the maintaining lesson plan on the equilibrium of cell issue, a lesson plan for learning how to communicate between cell and cell division. Students' learning achievements were assessed with the 30-item Assessment of Learning Biology Test (ALBT), students' perceptions of their satisfactions were satisfied with the 20-item Questionnaire on Students Satisfaction (QSS), and students' learning activities were assessed with the Mixed Media Internet-Based Instruction (MMIBI) on foundational cell issue was designed. The results of this research study have found that: statistically significant of students' post-learning achievements were higher than their pre-learning outcomes and indicated that the differences were significant at the .05 level. Students' performances of their satisfaction to their perceptions toward biology class with the mixed media according to internet-based multi instruction in biology on foundational cell issue were the highest level and evidence of average mean score as 4.59.

  3. Inhibition of Th1 and Th17 Cells by Medicinal Plants and Their Derivatives: A Systematic Review.

    Science.gov (United States)

    Asadi-Samani, Majid; Bagheri, Nader; Rafieian-Kopaei, Mahmoud; Shirzad, Hedayatollah

    2017-08-01

    Searching for new natural drugs that are capable of targeting Th1 and Th17 may lead to development of more effective treatments for inflammatory and autoimmune diseases. Most of the natural drugs can be derived from plants that are used in traditional medicine and folk medicine. The aim of this systematic review is to identify and introduce plants or plant derivatives that are effective on inflammatory diseases by inhibiting Th1 and Th17 responses. To achieve this purpose, the search terms herb, herbal medicine, herbal drug, medicinal plant, phytochemical, traditional Chinese medicine, Ayurvedic medicine, natural compound, inflammation, inflammatory diseases, Th1, Th17, T helper 1 or T helper 17 were used separately in Title/Keywords/Abstract in Web of Science and PubMed databases. In articles investigating the effect of the medicinal plants and their derivatives in inhibiting Th1 and Th17 cells, the effects of eight extracts of the medicinal plants, 21 plant-based compounds and some of their derivatives, and eight drugs derived from the medicinal plants' compounds in inhibiting Th1 and Th17 cells were reviewed. The results showed that medicinal plants and their derivates are able to suppress Th17 and Th1 T cell functions as well as cytokine secretion and differentiation. The results can be used to produce herbal drugs that suppress Th, especially Th17, responses. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  4. Cooperating learning in two Norwegian schools

    OpenAIRE

    Konkola, Happy Musonda; Mutale, Moses

    2014-01-01

    GK 300 Global Knowledge 16th May, 2014 Norway is one of the secular-rational nations. These nations practice the culture of high modernity in which autonomy and individualism are virtues. This write-up tries to find out whether individualism does or does not adversely affect cooperative learning at Kvåle and Feios Schools.

  5. Short report The DeDiMa battery: a tool for identifying students’ mathematical learning profiles

    Directory of Open Access Journals (Sweden)

    Giannis Karagiannakis

    2014-10-01

    Full Text Available Background The DeDiMa battery is designed for assessing students’ mathematical learning profiles, and it has been used to validate a 4-dimensional model for classifying mathematical learning difficulties. The model arises from existing hypotheses in the cognitive psychology and neuroscience literature, while the DeDiMa battery provides a reliable set of mathematical tasks that help to match characteristics of students’ mathematical performances to their more basic learning difficulties. Participants and procedure In this report we address the question of how these tools can help sketch out a student’s mathematical learning profile. The participants are 5th and 6th grade students. Results We compare the emerging profiles of two students with mathematical learning difficulties (MLD matched for age, performance on a standardized test, non-verbal IQ, and educational experiences. The profiles are very different. Conclusions We believe that this approach can inform the design of individualized remedial interventions for MLD students.

  6. Developmental Thyroid Hormone (TH) Disruption: In Search of Sensitive Bioindicators of Altered TH-Dependent Signaling in Brain

    Science.gov (United States)

    Thyroid hormones (TH) are essential for brain development, yet clear indicators of disruption at low levels of TH insufficiency have yet to be identified. Brain TH is difficult to measure, but TH-responsive genes can serve as sensitive indicators of TH action in brain. A large nu...

  7. Developmental Thyroid Hormone (TH) Disruption: In Search of Sensitive Bioindicators of Altered TH-Dependent Signaling in Brain###

    Science.gov (United States)

    Thyroid hormones (TH) are essential for brain development, yet clear indicators of disruption at low levels of TH insufficiency have yet to be identified. Brain TH is difficult to measure, but TH-responsive genes can serve as sensitive indicators of TH action in brain. A large nu...

  8. [Motivation and self-directed learning among medical students].

    Science.gov (United States)

    Fasce H, Eduardo; Ortega B, Javiera; Ibáñez G, Pilar; Márquez U, Carolina; Pérez V, Cristhian; Bustamante D, Carolina; Ortiz M, Liliana; Matus B, Olga; Bastías V, Nancy; Espinoza P, Camila

    2016-05-01

    Motivation is an essential aspect in the training process of medical students. The association that motivation can have with learning self-regulation is of utmost importance for the design of curriculum, teaching methods and evaluation. To describe the motivational aspects of self-directed learning among medical students from a traditional Chilean University. A qualitative, descriptive study based on grounded theory of Strauss and Corbin. Twenty 4th and 5th year medical students were selected using a maximum variation sampling technique. After obtaining an informed consent, semi-structured interviews and field notes were carried out. Data were analyzed to the level of open coding through Atlas-ti 7.5.2. From the student point of view, personal motivational aspects are linked to the search for information, constant updating, the perception of the physician-patient relationship and interest in subject matters. From the scope of teachers, a main issue is related to their ability to motivate students to develop independent study skills. Personal motivational aspects facilitate the development of independent study skills, specifically in the search of information. The role of teachers is crucial in promoting these skills and the perception of medical students from their learning process.

  9. Learning knowledge as an integral part of competencies in higher education: Effects on students' knowledge

    NARCIS (Netherlands)

    Van Bommel, Marijke; Boshuizen, Els; Kwakman, Kitty

    2011-01-01

    Van Bommel, M., Boshuizen, H. P. A., & Kwakman, K. (2010, 25-27 August). Learning knowledge as an integral part of competencies in higher education: Effects on students' knowledge. Paper presented at the 5th EARLI-SIG14 Learning and Professional Development, Munich, Germany.

  10. Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

    DEFF Research Database (Denmark)

    Prajeeth, Chittappen K; Kronisch, Julius; Khorooshi, Reza M. H.

    2017-01-01

    Background: Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously we have shown that only Th1...... mice where trafficking of Th1 cells into the CNS was affected. We compared microglia and astrocyte response in the brain and spinal cord of these mice. We further treated astrocytes with supernatants from highly pure Th1 and Th17 cultures and assessed the mRNA expression of neurotrophic factors......, cytokines and chemokines using real-time PCR. Data obtained was analysed using Kruskal- Wallis test. Results: We observed in α4-deficient mice weak microglial activation but comparable astrogliosis to that of wild-type mice in the regions of the brain populated with Th17 infiltrates suggesting that Th17...

  11. 41 CFR 101-26.505-4-101-26.505-6 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true [Reserved] 101-26.505-4-101-26.505-6 Section 101-26.505-4-101-26.505-6 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 26...

  12. Abstratcs of the 5th American Rabbit Congress

    Directory of Open Access Journals (Sweden)

    5th American Rabbit Congress Toluca, Estado de México, Mexico, September 8-11, 2014

    2015-03-01

    Full Text Available The 5th American Rabbit Congress was held in Toluca, Mexico State, Mexico from September 8th to the 11th, 2014. Research works representing 14 countries were accepted to take part at the congress, including papers from Algeria, Argentina, Brazil, China, Costa Rica, Cuba, Egypt, France, Hungary, Italy, México, Uruguay, the USA and Venezuela. These research works highlight the enormous interest, effort and commitment of the scientific community that bonds the trinomium of Research+Innovation+Technology Transfer, in favour of the integral development of rabbit rearing as an important primary activity that generates permanent employment, as well as healthy and nutritive meals for their respective countries for the XXI Century World. One major impact at this 5th American Rabbit Congress was the participation of Argentina, Brazil and China. The latter country’s report was presented by Laping Wu and Dong Wang (2014, showing that from 2005 to 2010, meat production of swine, beef and poultry underwent average growth of 2.6%, whereas rabbit meat production reported an annual average growth of 6.29%, reaching an annual volume of 761 000 tons, positioning China as the world’s main rabbit meat producer. This data highlights the great potential of rabbit production, both as an economic activity and a key strategy in the fight against hunger and poverty in many countries all over the world. During the congress, scientific works were presented related with the fields of Ethology, Housing & Welfare; Genetics; Reproduction; Digestive Physiology and Basic Nutrition; Feed Evaluation and Feeding; Pathology & Hygiene, Meat Quality, Safety & Dining; Management, Social & Economy. Furthermore, the meeting of the AB-WRSA chaired by the AB-WRSA founder, Dr. Steven Lukefahr, also took place at this congress, in which the new board of the American Branch was elected and the proposal put forward for the next American Rabbit Congress to be held in Costa

  13. Grade Level Differences in High School Students' Conceptions of and Motives for Learning Science

    Science.gov (United States)

    Wang, Ya-Ling; Tsai, Chin-Chung

    2017-08-01

    Students' conceptions of learning science and their relations with motive for learning may vary as the education level increases. This study aimed to compare the quantitative patterns in students' conceptions of learning science (COLS) and motives for learning science (MLS) across grade levels by adopting two survey instruments. A total of 768 high school students were surveyed in Taiwan, including 204 eighth graders, 262 tenth graders, and 302 12th graders. In the current research, memorizing, testing, and calculating and practicing were categorized as reproductive conceptions of learning science, while increase of knowledge, applying, understanding and seeing-in-a-new-way were regarded as constructivist conceptions. The results of multivariate analyses of variance (MANOVA) revealed that conceptions of learning science are more constructivist as education level increases. Both tenth graders and 12th graders endorsed understanding, seeing-in-a-new-way, and the constructivist COLS composite more strongly than the eighth graders did. In addition, the results of multigroup structural equation modeling (SEM) analysis indicated that the positive relations between testing and reproductive COLS were stronger as the grade level increased, while the negative relations between reproductive COLS and deep motive were tighter with the increase in grade level.

  14. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference (25th, Tarrytown, New York, March 25-26, 2011)

    Science.gov (United States)

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2011-01-01

    Conference proceedings of the 25th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2011 was: The Future of the Undergraduate Psychology Major: New Directions in an Evolving Educational Climate. The Conference…

  15. A Model of Small-Group Problem-Based Learning in Pharmacy Education: Teaching in the Clinical Environment

    Science.gov (United States)

    Khumsikiew, Jeerisuda; Donsamak, Sisira; Saeteaw, Manit

    2015-01-01

    Problem-based Learning (PBL) is an alternate method of instruction that incorporates basic elements of cognitive learning theory. Colleges of pharmacy use PBL to aid anticipated learning outcomes and practice competencies for pharmacy student. The purpose of this study were to implement and evaluate a model of small group PBL for 5th year pharmacy…

  16. Natural killer cells regulate Th1/Treg and Th17/Treg balance in chlamydial lung infection.

    Science.gov (United States)

    Li, Jing; Dong, Xiaojing; Zhao, Lei; Wang, Xiao; Wang, Yan; Yang, Xi; Wang, Hong; Zhao, Weiming

    2016-07-01

    Natural killer (NK) cell is an important component in innate immunity, playing a critical role in bridging innate and adaptive immunity by modulating the function of other immune cells including T cells. In this study, we focused on the role of NK cells in regulating Th1/Treg and Th17/Treg balance during chlamydial lung infection. We found that NK cell-depleted mice showed decreased Th1 and Th17 cells, which was correlated with reduced interferon-γ, interleukin (IL)-12, IL-17 and IL-22 production as well as T-bet and receptor-related orphan receptor gamma t expression compared with mice treated with the isotype control antibody. In contrast, NK cell depletion significantly increased Treg in cell number and related transcription factor (Foxp3) expression. The opposite trends of changes of Th1/Th17 and Treg led to significant reduction in the Th1/Treg and Th17/Treg ratios. The data implicate that NK cells play an important role in host defence against chlamydial lung infection, mainly through maintaining Th1/Treg and Th17/Treg balance. © 2016 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

  17. Learning Environment as Correlates of Chemistry Students ...

    African Journals Online (AJOL)

    gold

    2012-07-26

    Jul 26, 2012 ... The study aimed at assessing how 13 learning environment variables taken ... chemistry education programmes for optimum achievement of students in ... The contribution of chemistry and chemists to social, industrial and.

  18. Advance Organizers and Examining of their Usage in 9th Grade Chemistry Textbooks

    OpenAIRE

    Canan NAKİBOĞLU; Nihan KAŞMER; Cem GÜLTEKİN; Füsun DÖNMEZ

    2010-01-01

    An advance organizer is the tool that is presented prior to the material to be learned, and that helps learners to organize and interpret new incoming information. In this study, a concept map concerning the classification of advance organizer was developed. Then, 9th grade chemistry textbooks written according to both current (year 2007) and past (year 1996) high school chemistry curriculum were examined by taking into account the concept map prepared. Next, the findings of each textbook ana...

  19. Regulatory Effect of Catalpol on Th1/Th2 cells in Mice with Bone Loss Induced by Estrogen Deficiency.

    Science.gov (United States)

    Lai, Nannan; Zhang, Jianhai; Ma, Xingyan; Wang, Bin; Miao, Xiuming; Wang, Zhaoxia; Guo, Yuqi; Wang, Li; Yao, Chengfang; Li, Xia; Jiang, Guosheng

    2015-12-01

    Estradiol (E2 ) deficiency can cause bone loss and the skew of Th1/Th2 cells. However, the correlation between the Th1/Th2 cells and the bone loss induced by estrogen deficiency remains unclear. Our aim was to investigate the role of Th1/Th2 in bone loss induced by estrogen deficiency and elucidated the therapeutical effect of catalpol in this condition. Young, sham-operated (Sham), ovariectomized (Ovx), and naturally aged mice, treated with catalpol at different doses or control vehicle, were used in this study as indicated in each experiment. ELISA assay, dual-energy X-ray absorptiometry, and flow cytometry were used to analyze E2 , C-terminal telopeptides of type I collagen (CTx-I), bone mineral density (BMD), and Th1/Th2 subsets, respectively. The mRNA and protein expressions of specific transcription factors for Th1/Th2 cells (T-bet and GATA-3) were analyzed using real-time quantitative PCR and Western blot, respectively. Bone mineral density and E2 levels positively correlated with the proportion of Th2 subset while negatively correlated with that of Th1 subset and the ratio of Th1/Th2. Catalpol alleviated bone loss effectively by regulating Th1/Th2 polarization. Catalpol promoted the expression of Th2-specific transcription factors while inhibited that associated with Th1. Th1/Th2 skew is involved in bone loss induced by estrogen deficiency. Catalpol alleviates bone loss effectively by regulating Th1/Th2 paradigm. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. The cytokine polymorphisms affecting Th1/Th2 increase the susceptibility to, and severity of, chronic ITP.

    Science.gov (United States)

    Takahashi, Noriyuki; Saitoh, Takayuki; Gotoh, Nanami; Nitta, Yasuhiro; Alkebsi, Lobna; Kasamatsu, Tetsuhiro; Minato, Yusuke; Yokohama, Akihiko; Tsukamoto, Norifumi; Handa, Hiroshi; Murakami, Hirokazu

    2017-05-16

    T-helper cell type 1 (Th1) polarization in chronic immune thrombocytopenia (cITP) has been reported at the protein and mRNA levels. We evaluated the impact of Th1/Th2 cytokine and cytokine receptor functional polymorphisms on both susceptibility to, and severity of, cITP. We analysed IFN-γ + 874 T/A, IFN-γR -611G/A, IL-4 -590C/T, and IL-4Rα Q576R polymorphisms in 126 cITP patients (male/female: 34/92; median age: 47.7 years) and 202 healthy control donors. Genotyping was determined by PCR and direct sequencing. The Th1/Th2 ratio was detected in peripheral blood mononuclear cells via flow cytometry. cITP patients had a higher frequency of the IL-4Rα 576 non-QQ genotype compared to healthy subjects (P = 0.04). cITP patients with the IFN-γ +874 non-AA genotype (high expression type) showed more severe thrombocytopenia than those with the AA genotype (P Th1/Th2 ratio than control patients (P Th1/Th2 ratio (P Th1/Th2 increase the susceptibility to, and severity of, chronic ITP.

  1. 9th International Bielefeld Conference 2009: Upgrading the eLibrary: Enhanced Information Services Driven by Technology and Economics

    Directory of Open Access Journals (Sweden)

    Almuth Gastinger

    2009-10-01

    Full Text Available Thisarticle reports on the 9th International Bielefeld Conference ‘Upgrading the eLibrary: Enhanced Information Services Driven by Technology and Economics’, 3-5 February 2009, in Bielefeld, Germany. The conference focused on future challenges for libraries regarding the development of information services and infrastructures that meet the changing needs of scholarly communication, collaboration (e-science and publication (open access as well as new requirements regarding teaching and learning (virtual learning spaces. In addition attention was paid to economic conditions and strategic positioning of libraries as a general framework for information services.

  2. U and Th background contents in the Crimea rocks, Th/U ratio interpretation

    International Nuclear Information System (INIS)

    Gerasimov, Yu.G.; Voronova, M.A.; AN Ukrainskoj SSR, Kiev. Inst. Geologicheskikh Nauk)

    1981-01-01

    Radiogeochemical sampling of rocks in the Crimea is carried out. Analyses for U are made by luminescence method, while for Th by X-ray one. About 1000 samples, characterizing the whole stratigraphical cross section except Pz of crystalline rocks, have been analyzed. Low background values for U and Th are established; U content of 1.3-2.3 g/kg and Th content of 7.0-9.0 g/kg are predominant, that is lower than the clark of the earth crust. The distribution of radioelements in stepper and submontane Crimea is gradual, while in mountain part - the mosaic one. Results of Th/U ratios interpretation are presented [ru

  3. The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour

    Directory of Open Access Journals (Sweden)

    Lynne Sykes

    2012-01-01

    Full Text Available Pregnancy is a unique immunological state in which a balance of immune tolerance and suppression is needed to protect the fetus without compromising the mother. It has long been established that a bias from the T helper 1 cytokine profile towards the T helper 2 profile contributes towards successful pregnancy maintenance. The majority of publications that report on aberrant Th1:Th2 balance focus on early pregnancy loss and preeclampsia. Over the last few decades, there has been an increased awareness of the role of infection and inflammation in preterm labour, and the search for new biomarkers to predict preterm labour continues. In this paper, we explore the evidence for an aberrant Th1:Th2 profile associated with preterm labour. We also consider the potential for its use in screening women at high risk of preterm labour and for prophylactic therapeutic measures for the prevention of preterm labour and associated neonatal adverse outcomes.

  4. Conceptual Understanding of Acids and Bases Concepts and Motivation to Learn Chemistry

    Science.gov (United States)

    Cetin-Dindar, Ayla; Geban, Omer

    2017-01-01

    The purpose of this study was to investigate the effect of 5E learning cycle model oriented instruction (LCMI) on 11th-grade students' conceptual understanding of acids and bases concepts and student motivation to learn chemistry. The study, which lasted for 7 weeks, involved two groups: An experimental group (LCMI) and a control group (the…

  5. Increased Th1/Th17 Responses Contribute to Low-Grade Inflammation in Age-Related Macular Degeneration.

    Science.gov (United States)

    Chen, Jiajia; Wang, Wenzhan; Li, Qiuming

    2017-01-01

    Age-related macular degeneration (AMD) is the primary cause of senior blindness in developed countries. Mechanisms underlying initiation and development of AMD remained known. We examined the CD4+ T cell compartments and their functions in AMD patients. AMD patients presented significantly higher frequencies of interferon (IFN)-γ-expressing and interleukin (IL)-17-expressing CD4+ T cells than healthy controls. The levels of IFN-γ and IL-17 expression by CD4+ T cells were significantly higher in AMD patients. These IFN-γ-expressing Th1 cells and IL-17-expressing Th17 cells could be selectively enriched by surface CCR3+ and CCR4+CCR6+ expression, respectively. Th1 and Th17 cells from AMD patients promoted the differentiation of monocytes toward M1 macrophages, which were previously associated with retinal damage. Th1 and Th17 cells also increased the level of MHC class I expression in human retinal pigment epithelial (RPE)-1 cells, while Th1 cells increased the frequency of MHC class II-expressing RPE-1 cells. These proinflammatory effects were partly, but not entirely, induced by the secretion of IFN-γ and IL-17. This study demonstrated an enrichment of Th1 cells and Th17 cells in AMD patients. These Th1 and Th17 cells possessed proinflammatory roles in an IFN-γ- and IL-17-dependent fashion, and could potentially serve as therapeutic targets. © 2017 The Author(s). Published by S. Karger AG, Basel.

  6. A tool for the auto-management of Units of Learning: the Link Tool

    NARCIS (Netherlands)

    Pérez-Sanagustín, Mar; Cherian, Roy; Hernández-Leo, Davinia; Griffiths, Dai; Blat, Josep

    2009-01-01

    Pérez-Sanagustín, M., Cherian, R., Hernández-Leo, D., Griffiths, D., & Blat, J. (2010). A tool for the auto-management of Units of Learning: the Link Tool. In D. Griffiths, & R. Koper (Eds.), Rethinking Learning and Employment at a Time of Economic Uncertainty. Proceedings of the 6th TENCompetence

  7. Scenario analysis for estimating the learning rate of photovoltaic power generation based on learning curve theory in South Korea

    International Nuclear Information System (INIS)

    Hong, Sungjun; Chung, Yanghon; Woo, Chungwon

    2015-01-01

    South Korea, as the 9th largest energy consuming in 2013 and the 7th largest greenhouse gas emitting country in 2011, established ‘Low Carbon Green Growth’ as the national vision in 2008, and is announcing various active energy policies that are set to gain the attention of the world. In this paper, we estimated the decrease of photovoltaic power generation cost in Korea based on the learning curve theory. Photovoltaic energy is one of the leading renewable energy sources, and countries all over the world are currently expanding R and D, demonstration and deployment of photovoltaic technology. In order to estimate the learning rate of photovoltaic energy in Korea, both conventional 1FLC (one-factor learning curve), which considers only the cumulative power generation, and 2FLC, which also considers R and D investment were applied. The 1FLC analysis showed that the cost of power generation decreased by 3.1% as the cumulative power generation doubled. The 2FCL analysis presented that the cost decreases by 2.33% every time the cumulative photovoltaic power generation is doubled and by 5.13% every time R and D investment is doubled. Moreover, the effect of R and D investment on photovoltaic technology took after around 3 years, and the depreciation rate of R and D investment was around 20%. - Highlights: • We analyze the learning effects of photovoltaic energy technology in Korea. • In order to calculate the learning rate, we use 1FLC (one-factor learning curve) and 2FLC methods, respectively. • 1FLC method considers only the cumulative power generation. • 2FLC method considers both cumulative power generation and knowledge stock. • We analyze a variety of scenarios by time lag and depreciation rate of R and D investment

  8. Teaching Gases through Problem-Based Learning

    Science.gov (United States)

    Baran, Mukadder

    2016-01-01

    The purpose of this study was to investigate not only the applicability of the method of Problem-Based Learning (PBL) to the lesson subject of "Gasses" within the scope of the 9th grade course of Chemistry in Hakkari Gazi High School but also the influence of this method on the students' achievement levels in chemistry and on their…

  9. 11th Edoardo Amaldi Conference on Gravitational Waves (AMALDI 11)

    International Nuclear Information System (INIS)

    Lee, Hyung Mok; Oh, John

    2016-01-01

    The 11 th Amaldi Conference on gravitational waves was held from June 21 to 26, 2016 in Gwangju, Korea. This meeting was sponsored by the International Union of Pure and Applied Physics (IUPAP), Korean Astronomical Society, Korean Physical Society, Korean Federation of Science and Technology (KOFST), National Research Foundation (NRF), Korea Tourism Organism, and Gwangju Convention Bureau. More than 150 scientists from 26 countries attended the 11 th Amaldi Confernece. Although there was an outbreak of Middle East Respiratory Syndrome (MERS) just before the conference, there were very little cancellations. There was no incident related to the MERS disease. The scientific program, including the list of the invited plenary speakers, was arranged by the Gravitational Wave International Committee (GWIC) chaired by Eugenio Coccia. Most of the communication between the GWIC and the Local Organizing Committee (LOC) was handled by Stan Whitcomb, general secretary of the GWIC. There were 10 plenary sessions and 13 parallel sessions. Two plenary sessions were held each morning from Monday to Friday while the afternoon was devoted to parallel sessions. A special lecture for the participants of the meeting on ultra-high intensity lasers was delivered by Chang Hee Nam, director of the Center for Relativistic Laser Science located at the Gwangju Institute of Science and Technology. Bernard Schutz gave a public talk entitled “Listening to Black Holes and the Big Bang - the Oldest Concert of the Universe” in the evening on June 23. More than 250 students and general public attended this talk. Most of the topics ranging from detector instruments, data analysis, to astrophysics and source modeling were covered in 10 invited talks, 67 contributed oral presentations, and 39 posters. After the conference, we invited all participants to submit written papers for proceedings. We received 35 papers and went through the peer review process and accepted 34 papers for publications. We

  10. Learning Representation and Control in Markov Decision Processes

    Science.gov (United States)

    2013-10-21

    449–456. MIT Press, 2006. [35] D. Koller and N. Friedman. Graphical Models. MIT Press, 2009. [36] J. Zico Kolter and Andrew Y. Ng. Regularization and...ICML ’09, pages 521–528, New York, NY, USA, 2009. ACM. [37] J. Zico Kolter and Andrew Y. Ng. Regularization and feature selection in least-squares...temporal differ- ence learning. In Proceedings of 27 th International Conference on Machine Learning, 2009. [38] J. Zico Z. Kolter . The Fixed Points of Off

  11. The Effect of Project-Based Learning on Students' Statistical Literacy Levels for Data Representation

    Science.gov (United States)

    Koparan, Timur; Güven, Bülent

    2015-01-01

    The point of this study is to define the effect of project-based learning approach on 8th Grade secondary-school students' statistical literacy levels for data representation. To achieve this goal, a test which consists of 12 open-ended questions in accordance with the views of experts was developed. Seventy 8th grade secondary-school students, 35…

  12. Development Biology Worksheet Oriented Accelerated Learning on Plantae and Ecosystems for 10th-Grade Senior High School Students

    Science.gov (United States)

    Dipuja, D. A.; Lufri, L.; Ahda, Y.

    2018-04-01

    The problem that found are learning outcomes student is low on the plantae and ecosystems. Students less motivated and passive learning because learning is teacher center and teaching materials not facilitate student. Therefore, it is necessary to design a worksheet oriented accelerated learning. Accelerated learning approach that can improve motivation and learning activities. The purpose of the research was to produce worksheet oriented accelerated learning on plantae and ecosystems. This research is designed as a research and development by using Plomp model, consists of the preliminary, prototyping, and assessment phase. Data was collected through questionnaires, observation sheet, test, and documentation. The results of the research was worksheet oriented accelerated learning on plantae and ecosystems is very valid.

  13. 26 CFR 26.2653-1 - Taxation of multiple skips.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Taxation of multiple skips. 26.2653-1 Section 26.2653-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) ESTATE...-1 Taxation of multiple skips. (a) General rule. If property is held in trust immediately after a GST...

  14. How medical education can contribute towards the reduction of maternal mortality in Angola: the teaching/learning process of Gynecology and Obstetrics.

    Science.gov (United States)

    Mendes, M; Barbosa, J; Loureiro, E; Ferreira, M A

    2014-03-01

    In Angola the maternal mortality ratio is among the highest in the world. Medical students are an important target for intervention. To evaluate how students perceive the curricular unit of Gynecology and Obstetrics (G&O) in a public institution of reference in Angola. The study involved a sample of 147 students of the faculty of Medicine of the University Agostinho Neto, Luanda, Angola, attending the curricular unit of G&O in the 5th and 6th years of the medical course. Data were obtained through surveys of opinion. The information of the scales was summarized through the construction of scores from the original items using the Principal Components Analysis. Students evaluated positively the curricular unit although emphasizing the lack of human and physical resources. The 5th year scored with higher values Teacher Performance and 6th year Students' Performance. Both years considered to have insufficient skills to meet the learning objectives. Constraints were identified in the outcomes of the teaching/learning program. Several points emerged as crucial from this study: widespread the areas of teaching/learning, increase the number and quality of teaching staff, improve the monitoring of students and provide adequate infrastructures and medical equipment to support the teaching/learning program.

  15. Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro

    International Nuclear Information System (INIS)

    Yang, Xia; Qian, Feng; He, Hai-Yang; Liu, Kai-Jun; Lan, Yuan-Zhi; Ni, Bing; Tian, Yi; Fu, Xiao-Lan; Zhang, Ji; Shen, Zi-Gang; Li, Jian; Yin, Yi; Li, Jin-Tao; Wu, Yu-Zhang

    2011-01-01

    Thymosin alpha 1 (Tα1) has been shown to have beneficial effects on numerous immune system parameters, but little is known about the effects of Tα1 on patients with gastric carcinoma. The objective of this study was to determine the effect of Tα1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro, and to evaluate its efficacy as an immunoregulatory factor in patients with gastric carcinoma. We compared the effect of Tα1 on the frequency of CD4 + and CD8 + T cells, especially the CD4 + CD25 + Foxp3 + Tregs in peripheral blood mononuclear cells (PBMCs) from gastric carcinoma patients (N = 35) and healthy donors (N = 22). We also analyzed the changes in the proliferation of PBMCs in response to treatment with Tα1, and examined the production of Th1, Th2, and Th17 cytokines by PBMCs and tumor-infiltrating lymphocytes. The treatment of PBMCs from gastric cancer patients, with Tα1 (50 µg/mL) alone increased the percentage of CD4+CD25+Foxp3+ (suppressive antitumor-specific Tregs) from 1.68 ± 0.697 to 2.19 ± 0.795% (P < 0.05). Our results indicate that Tα1 increases the percentage of Tregs and IL-1β, TNF-α, and IL-6 in vitro

  16. Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Xia [Institute of Immunology,Third Military Medical University, Chongqing (China); Qian, Feng [Department of General Surgery, Southwest Hospital, Third Military Medical University, Chongqing (China); He, Hai-Yang; Liu, Kai-Jun [Institute of Immunology,Third Military Medical University, Chongqing (China); Lan, Yuan-Zhi [Department of General Surgery, Southwest Hospital, Third Military Medical University, Chongqing (China); Ni, Bing; Tian, Yi; Fu, Xiao-Lan; Zhang, Ji; Shen, Zi-Gang; Li, Jian; Yin, Yi; Li, Jin-Tao; Wu, Yu-Zhang [Institute of Immunology,Third Military Medical University, Chongqing (China)

    2011-12-02

    Thymosin alpha 1 (Tα1) has been shown to have beneficial effects on numerous immune system parameters, but little is known about the effects of Tα1 on patients with gastric carcinoma. The objective of this study was to determine the effect of Tα1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro, and to evaluate its efficacy as an immunoregulatory factor in patients with gastric carcinoma. We compared the effect of Tα1 on the frequency of CD4{sup +} and CD8{sup +} T cells, especially the CD4{sup +}CD25{sup +}Foxp3{sup +} Tregs in peripheral blood mononuclear cells (PBMCs) from gastric carcinoma patients (N = 35) and healthy donors (N = 22). We also analyzed the changes in the proliferation of PBMCs in response to treatment with Tα1, and examined the production of Th1, Th2, and Th17 cytokines by PBMCs and tumor-infiltrating lymphocytes. The treatment of PBMCs from gastric cancer patients, with Tα1 (50 µg/mL) alone increased the percentage of CD4+CD25+Foxp3+ (suppressive antitumor-specific Tregs) from 1.68 ± 0.697 to 2.19 ± 0.795% (P < 0.05). Our results indicate that Tα1 increases the percentage of Tregs and IL-1β, TNF-α, and IL-6 in vitro.

  17. Preface to Special Topic: Selected Papers from the 5th International Conference on Optofluidics.

    Science.gov (United States)

    Fan, Shih-Kang; Yang, Zhenchuan

    2016-01-01

    The 5th International Conference on Optofluidics (Optofluidics 2015) was held in Taipei, Taiwan, July 26-29, 2015. The aim of this conference was to provide a forum to promote scientific exchange and to foster closer networks and collaborative ties between leading international researchers in optics and micro/nanofluidics across various disciplines. The scope of Optofluidics 2015 was deliberately broad and interdisciplinary, encompassing the latest advances and the most innovative developments in micro/nanoscale science and technology. Topics ranged from fundamental research to its applications in chemistry, physics, biology, materials, and medicine.

  18. Teachable Agents and the Protégé Effect: Increasing the Effort Towards Learning

    Science.gov (United States)

    Chase, Catherine C.; Chin, Doris B.; Oppezzo, Marily A.; Schwartz, Daniel L.

    2009-08-01

    Betty's Brain is a computer-based learning environment that capitalizes on the social aspects of learning. In Betty's Brain, students instruct a character called a Teachable Agent (TA) which can reason based on how it is taught. Two studies demonstrate the protégé effect: students make greater effort to learn for their TAs than they do for themselves. The first study involved 8th-grade students learning biology. Although all students worked with the same Betty's Brain software, students in the TA condition believed they were teaching their TAs, while in another condition, they believed they were learning for themselves. TA students spent more time on learning activities (e.g., reading) and also learned more. These beneficial effects were most pronounced for lower achieving children. The second study used a verbal protocol with 5th-grade students to determine the possible causes of the protégé effect. As before, students learned either for their TAs or for themselves. Like study 1, students in the TA condition spent more time on learning activities. These children treated their TAs socially by attributing mental states and responsibility to them. They were also more likely to acknowledge errors by displaying negative affect and making attributions for the causes of failures. Perhaps having a TA invokes a sense of responsibility that motivates learning, provides an environment in which knowledge can be improved through revision, and protects students' egos from the psychological ramifications of failure.

  19. Electrochemical behavior of Th(IV) and its electrodeposition from ThF_4-LiCl-KCl melt

    International Nuclear Information System (INIS)

    Wang, Xianbin; Huang, Wei; Gong, Yu; Jiang, Feng; Zheng, Haiyang; Zhu, Tiejian; Long, Dewu; Li, Qingnuan

    2016-01-01

    The electrochemical behavior of Th(IV) ion on molybdenum (Mo) electrode was studied by cyclic voltammetry (CV) and square wave voltammetry (SWV) technologies at 773 K in ThF_4-LiCl-KCl melt. The reduction of Th(IV) to metal Th at −1.67 V (vs. Ag/AgCl) is a four-electron exchange process, which is quasi-reversible and diffusion-controlled. The diffusion coefficient (D) and activation energy of diffusion process for Th(IV) were determined to be 3.77 × 10"−"5 cm"2 s"−"1 and 59.2 kJ mol"−"1. The pulse potential electrolysis of ThF_4-LiCl-KCl melt revealed that 86.8% of Th(IV) can be separated from the melt based on the inductively coupled plasma atomic emission spectrometer (ICP-AES) results.

  20. 4th French-German Conference on Optimization

    CERN Document Server

    Zowe, Jochem; Hiriart-Urruty, Jean-Baptiste; Lemarechal, Claude

    1988-01-01

    This volume contains a collection of 23 papers presented at the 4th French-German Conference on Optimization, hold at Irsee, April 21 - 26, 1986. The conference was aUended by ninety scientists: about one third from France, from Germany and from third countries each. They all contributed to a highly interesting and stimulating meeting. The scientifique program consisted of four survey lectures of a more tutorical character and of 61 contributed papers covering almost all areas of optimization. In addition two informal evening sessions and a plenary discussion on further developments of optimization theory were organized. One of the main aims of the organizers was to indicate and to stress the increasing importance of optimization methods for almost all areas of science and for a fast growing number of industry branches. We hope that the conference approached this goal in a certain degree and managed to continue fruitful discussions between -theory­ and -applications-. Equally important to the official contri...