Sample records for lateral instability due

  1. Subjeans Condensations due to a Thermal Instability (United States)

    Opher, R.; Valio, A.


    RESUMEN. Las observaciones recientes muestran que las nubes moleculares no son homogeneas, sino que tienen condensaciones. Se observa que estas condensaciones estan libres gravitacionalmente. C6mo se forman estas condensaciones? Sugerimos explicar estas conden sac jones como debidas a que la inestabilidad termica ayuda a la gravedad. Se estudi6 una funci5n de enfriamiento por gramo de la forma general A p T , en donde p y T son la densidad y la temperatura. Estamos interesados en el valor maximo de para la cual el colapso ocurre. Se estudiaron varios mode- los. Nuestros resultados indican que los valores de comparables con aquellos sugeridos por la literatura (1 < son suficientes para provocar el colapso de masas inferiores a la masa de Jeans por medio de inestabilidad termica, ayudada por gravedad y asi se forman las condensaciones libres gravitacionalmente. ABSTRACT: Recent observations show that molecular clouds are not homogeneous, but clumpy. Some clumps are observed to be gravitationally unbound. How did these clumps then form? We suggest explaining these condensation as due to thermal instability aiding gravit y The cooling function per gram studied is of the general form A p T,where pand T are the density and temperature, respectively. We are interested in the maximum value of for which collapse still occurs. Various models are studied. Our results indicate that values comparable to those suggested in the literature (1 < %< 2) are sufficient to trigger the collapse of subjeans masses by thermal instability, when aided by gravity, and form the observed gravitationally unbound clumps. Keq o : HYDRODYNAMICS - INTERSTELLAR CLOUDS

  2. Managing incontinence due to detrusor instability. (United States)


    Urinary incontinence affects around 3.5 million people of all ages in the UK. For many, incontinence severely restricts their routine activities and damages their quality of life and self-esteem. In about one-third of women sufferers, and around a half of all men with incontinence, the cause is detrusor instability. This condition is characterised by involuntary bladder contractions or pressure rises during bladder filling, which result in a strong or uncontrollable urge to pass urine and, often, incontinence. Here, we consider a primary care-based approach to managing urinary incontinence in adults, concentrating on the medical management of detrusor instability.

  3. Tearing mode instability due to anomalous resistivity

    Energy Technology Data Exchange (ETDEWEB)

    Furuya, Atsushi [Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Kasuga, Fukuoka (Japan); Itoh, Sanae I.; Yagi, Masatoshi [Kyushu Univ., Fukuoka (Japan). Research Inst. for Applied Mechanics


    Tearing mode instability in the presence of microscopic truculence is investigates. The effects of microscopic turbulence on tearing mode are taken as drags which are calculated by one-point renormalization method and mean-field approximation. These effects are reduced to effective diffusivities in reduced MHD equations. Using these equations, the stability analyses of the tearing mode are performed. It is shown that a finite amplitude of fluctuation enhances the growth rate of tearing mode. For very high values of turbulent diffusivities, marginally stable state exists. The effects of each turbulent diffusivity on mode stability are examined near marginal stability boundary. Parameter dependence of the resistive ballooning mode turbulence on tearing mode is analyzed as an example. (author)

  4. Coupled-bunch instabilities due to fundamental cavity impedance

    CERN Document Server

    Mastoridis, Themistoklis; Chapochnikova, Elena; Esteban Muller, Juan; Molendijk, John; Timko, Helga; CERN. Geneva. ATS Department


    The purpose of this MD was to estimate the stability threshold due to longitudinal coupled-bunch instabilities (CBIs) driven by the RF cavities' fundamental impedance. These instabilities are not a concern for the LHC. A model was developed to study the stability threshold for the High-Luminosity LHC (HL-LHC). The goal of this MD was to validate this model and thus its predictions for the HL-LHC stability margins.

  5. Lateral-Torsional Buckling Instability Caused by Individuals Walking on Wood Composite I-Joists (United States)

    Villasenor Aguilar, Jose Maria

    conditions. Three different lean-on bracing systems were investigated, non-bracing, one-bracing, and two-bracing systems. Mathematical models were derived to calculate the amount of constraint due to the lean-on bracing system. The derived mathematical models were validated by comparison to data from testing for all supported end conditions and bracing systems. The predicted critical loads using the static buckling theoretical models for the non-bracing system and the static buckling theoretical models combined with the bracing theoretical models for the simply and hanger supported end conditions agreed well with the critical loads obtained from testing for the two wood I-joist sizes investigated. The predicted maximum lateral displacements and individual positions using the bending motion theoretical models for the simply and hanger supported end conditions agreed well with the corresponding maximum lateral displacements and individual positions obtained from testing for both wood I-joist sizes. Results showed that; a) the supported end condition influenced the critical loads, maximum lateral displacements and individual positions, b) the bracing system increased the critical loads and reduced the maximum lateral displacements, c) the critical load increased as the load position displaced away from the wood I-joist mid-span, d) the critical load reduced as the initial lateral displacement of the wood I-joist increased and e) the wood I-joist mid-span was the critical point in the dynamic lateral-torsional buckling instability.

  6. Recalcitrant Lateral Premalleolar Bursitis of the Ankle Associated with Lateral Ankle Instability

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    Masashi Naito


    Full Text Available Lateral premalleolar bursitis of the ankle is a rarely reported disorder in the English literature although it is not uncommon in Asian countries where people commonly sit on their feet. Here, we present the case of a 66-year-old woman with recalcitrant lateral premalleolar bursitis associated with lateral ankle instability which was successfully treated with surgical resection of the bursa and repair of the anterior talofibular ligament. Operative findings revealed a communication between the bursa and articular cavity of the ankle joint via the sheath of the extensor digitorum longus tendon, which was considered to act as a check valve leading to a large and recalcitrant bursitis. This report provides a novel concept about the etiology of recalcitrant lateral premalleolar bursitis of the ankle.

  7. Particle creation due to tachyonic instability in relativistic stars

    Energy Technology Data Exchange (ETDEWEB)

    Landulfo, Andre G.S. [Universidade Federal do ABC (CCNH/UFABC), Santo Andre, SP (Brazil); Lima, William C.C.; Matsas, George E.A. [Universidade Estadual Paulista Julio de Mesquita Filho (IFT/UNESP), Sao Paulo, SP (Brazil); Vanzella, Daniel A.T. [Universidade de Sao Paulo (IFSC/USP), Sao Carlos, SP (Brazil). Instituto de Fisica


    Full text: It was recently shown that relativistic stars may become unstable due to quantum field effects. The so called vacuum awakening effect occurs for a free scalar field properly coupled to the spacetime curvature. This effect is characterized by an exponential point-dependent increase and decrease of the vacuum expectation value of the stress-energy-momentum tensor. This is caused by a tachyonic-like instability, which induces an exponential growth of the vacuum fluctuations. Once the effect is triggered, the star energy density would be overwhelmed by the vacuum energy density in a few milliseconds. This demands that eventually geometry and field evolve to a new configuration to bring the vacuum back to a stationary regime. Here, we show that the vacuum fluctuations built up during the unstable epoch lead to particle creation in the final stationary state when the tachyonic instability ceases. The amount of created particles depends mostly on the duration of the unstable epoch and final stationary configuration, which are open issues at this point. We emphasize that the particle creation coming from the tachyonic instability will occur even in the adiabatic limit, where the spacetime geometry changes arbitrarily slowly, and therefore is quite distinct from the usual particle creation due to the change in the background geometry. (author)

  8. Can Chronic Ankle Instability be Prevented? Rethinking Management of Lateral Ankle Sprains. (United States)

    Denegar, Craig R.; Miller, Sayers J., III


    Investigates whether chronic ankle instability can be prevented, discussing: the relationship between mechanical and functional instability; normal ankle mechanics, sequelae to lateral ankle sprains, and abnormal ankle mechanics; and tissue healing, joint dysfunction, and acute lateral ankle sprain management. The paper describes a treatment model…

  9. Simultaneous MPFL and LPFL reconstruction for recurrent lateral patellar dislocation with medial patellofemoral instability

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    Masashi Kusano


    Full Text Available We report an extremely rare case of both recurrent lateral patella dislocation and medial patellofemoral instability, following prior operations to correct patella maltracking. Manual translation of the patella revealed medial and lateral instability with a positive apprehension sign. 3-D computer modelling of kinematics based on MRI data demonstrated that the patella deviated laterally at full extension and translated medially with knee flexion. The medial and lateral patellofemoral ligaments were reconstructed simultaneously with hamstring tendons, alleviating peripatellar pain and patellar instability in both directions.

  10. Particle Acceleration in Relativistic Jets Due to Weibel Instability (United States)

    Nishikawa, K.-I.; Hardee, P.; Richardson, G.; Preece, R.; Sol, H.; Fishman, G. J.


    Shock acceleration is a ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, two-streaming instability, and the Weibel instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. Using a three-dimensional relativistic electromagnetic particle code, we have investigated particle acceleration associated with a relativistic jet front propagating through an ambient plasma with and without initial magnetic fields. We find only small differences in the results between no ambient and weak ambient magnetic fields. Simulations show that the Weibel instability created in the collisionless shock front accelerates particles perpendicular and parallel to the jet propagation direction. While some Fermi acceleration may occur at the jet front, the majority of electron acceleration takes place behind the jet front and cannot be characterized as Fermi acceleration. The simulation results show that this instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields, which contribute to the electron s transverse deflection behind the jet head. The "jitter" radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  11. Medio-lateral postural instability in subjects with tinnitus

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    Zoi eKapoula


    Full Text Available Background: Many patients show modulation of tinnitus by gaze, jaw or neck movements, reflecting abnormal sensorimotor integration and interaction between various inputs. Postural control is based on multi-sensory integration (visual, vestibular, somatosensory, and oculomotor and indeed there is now evidence that posture can also be influenced by sound. Perhaps tinnitus influences posture similarly to external sound. This study examines the quality of postural performance in quiet stance in patients with modulated tinnitus.Methods: Twenty-three patients with highly modulated tinnitus were selected in the ENT service. Twelve reported exclusively or predominately left tinnitus, eight right and three bilateral. Eighteen control subjects were also tested. Subjects were asked to fixate a target at 40cm for 51s; posturography was performed with the platform (Technoconcept, 40Hz for both the eyes open and eyes closed conditions.Results: For both conditions, tinnitus subjects showed abnormally high lateral body sway (SDx. This was corroborated by fast Fourrier Transformation (FFTx and wavelet analysis. For patients with left tinnitus only, medio-lateral sway increased significantly when looking away from the center. Conclusions: Similarly to external sound stimulation, tinnitus could influence lateral sway by activating attention shift, and perhaps vestibular responses. Poor integration of sensorimotor signals is another possibility. Such abnormalities would be accentuated in left tinnitus because of the importance of the right cerebral cortex in processing both auditory-tinnitus and attention.

  12. Anterior subluxation of the lateral tibial plateau. A new clinical test and the morbidity of this type of knee instability. (United States)

    Martens, M A; Mulier, J C


    A new clinical test is presented for the diagnosis of anterolateral knee instability. The advantages of the test are obviation of apprehension- and muscle spasm avoiding false negative results and also the recognition by the patient of his sensation of "collapsing at the knee". This allows for differentiation between "giving away" due to a torn meniscus alone and concomitant anterolateral knee instability. It implies important consequences for prognosis and treatment of the knee problem of the athlete. Underlying pathology consists of a torn anterior cruciate ligament and primary or secondary stretching of the soft tissues at the lateral and posterolateral capsule. These lesions and a positive test for anterolateral knee instability does not inevitably result in a disability for sports activity. The dynamic muscular control protects the knee in many instances from collapsing at cross over cutting.

  13. Reliability of MRI Findings of Peroneal Tendinopathy in Patients with Lateral Chronic Ankle Instability (United States)

    Park, Hee Jin; Kim, Hyung Soo; Chung, Soo Tae; Park, Noh Hyuck; Yoo, Jeong Hyun; Park, Jai Hyung; Kim, Joo Hak; Lee, Tae Woo; Lee, Chang Hyun; Oh, Se Man


    Background Patients with chronic lateral ankle instability also have peroneal tendinopathy often. However, preoperative MRIs of these patients are vague in many cases. Our study was performed to see the reliability of MRI findings of peroneal tendinopathy in patients with chronic lateral ankle instability. Methods MRI images for 82 patients who had chronic lateral ankle instability, and had received surgical treatment between March 2006 and November 2009 were compared with impressions from operating rooms. The mean age of patients was 36.4 years (range, 15 to 64 years), 82 ankles were studied, and patients with rheumatoid diseases were excluded from the study. Results Of the 82 cases, 26 were true positives, 38 true negatives, 13 false positives and 5 false negatives. Of 39 cases of peroneal tendinopathy diagnosed from MRI, 14 had peroneal tendon partial tears, 15 tenosynovitis, 3 dislocations, 17 low-lying muscle bellies, and 6 peroneus quartus muscles. Of 31 cases of peroneal tendinopathy observed in surgery 11 had peroneal tendon partial tears, 4 tenosynovitis, 5 dislocations, 12 low-lying muscle belliess, and 1 peroneus quartus muscle. Sensitivity and specificity of peroneal tendinopathy were 83.9% and 74.5%, respectively. Positive predictive value was 66.7%. Negative predictive value was 88.4%. Accuracy rate was 78.0%. Conclusions MRI is a useful diagnostic tool for detecting peroneal tendinopathy in patients with chronic lateral ankle instability. However, MRI is vague in many cases. Therefore, a thorough delicate physical examination and careful observation is needed. PMID:21119941

  14. Lateral collateral ligament reconstruction for chronic varus instability of the hallux interphalangeal joint. (United States)

    Cho, Jaeho


    Chronic varus instability of the hallux interphalangeal joint is a rare injury, and only a few reports of this injury have been published. In some studies, this injury has been related to taekwondo. Taekwondo is an essential martial art in the Korean military. We have described a case of varus instability of the hallux interphalangeal joint in a professional soldier who had practiced taekwondo for 5 years and the surgical outcome after reconstruction of the lateral collateral ligament with the fourth toe extensor tendon.

  15. Compression Myelopathy due to Proliferative Changes around C2 Pars Defects without Instability (United States)

    Kimura, Tetsuya; Tezuka, Fumitake; Abe, Mitsunobu; Yamashita, Kazuta; Takata, Yoichiro; Higashino, Kosaku; Sairyo, Koichi


    We report a case with compression myelopathy due to proliferative changes around the C2 pars defects without instability. A 69-year-old man presented with progressive clumsy hands and spastic gait. Plain radiographs showed bilateral spondylolysis (pars defects) at C2 and fusion between C2 and C3 spinous processes. Dynamic views revealed mobility through the pars defects, but there was no apparent instability. Computed tomography showed proliferative changes at the pars defects, which protruded into spinal canal. On magnetic resonance imaging, the spinal cord was compressed and intramedullary high signal change was found. A diagnosis of compression myelopathy due to proliferative changes around the C2 pars defects was made. We performed posterior decompression. Postoperatively, symptoms have been alleviated and images revealed sufficient decompression and no apparent instability. In patients with the cervical spondylolysis, myelopathy caused by instability or slippage have been periodically reported. The present case involving C2 spondylolysis is extremely rare. PMID:27340539

  16. Large negative lateral shifts due to negative refraction

    CERN Document Server

    Benedicto, Jessica; Moreau, Antoine; Centeno, Emmanuel


    When a thin structure in which negative refraction occurs (a metallo-dielectric or a photonic crystal) is illuminated by a beam, the reflected and transmitted beam can undergo a large negative lateral shift. This phenomenon can be seen as an interferential enhancement of the geometrical shift and can be considered as a signature of negative refraction.

  17. A probabilistic decomposition-synthesis method for the quantification of rare events due to internal instabilities

    CERN Document Server

    Mohamad, Mustafa A; Sapsis, Themistoklis P


    We consider the problem of probabilistic quantification of dynamical systems that have heavy-tailed characteristics. These heavy-tailed features are associated with rare transient responses due to the occurrence of internal instabilities. Here we develop a computational method, a probabilistic decomposition-synthesis technique, that takes into account the nature of internal instabilities to inexpensively determine the non-Gaussian probability density function for any arbitrary quantity of interest. Our approach relies on the decomposition of the statistics into a `non-extreme core', typically Gaussian, and a heavy-tailed component. This decomposition is in full correspondence with a partition of the phase space into a `stable' region where we have no internal instabilities, and a region where non-linear instabilities lead to rare transitions with high probability. We quantify the statistics in the stable region using a Gaussian approximation approach, while the non-Gaussian distributions associated with the i...

  18. Oscillatory instability of three-dimensional natural convection of air in a laterally heated cubic box

    CERN Document Server

    Gelfgat, Alexander


    Transition from steady to oscillatory buoyancy convection of air in a laterally heated cubic box is studied numerically by straight-forward time integration of Boussinesq equations using a series of gradually refined finite volume grids. Horizontal and spanwise cube boundaries are assumed to be either perfectly thermally conducting or perfectly thermally insulated, which results in four different sets of thermal boundary conditions. Critical Grashof numbers are obtained by interpolation of numerically extracted growth/decay rates of oscillations amplitude to zero. Slightly supercritical flow regimes are described by time-averaged flows, snapshots, and spatial distribution of oscillations amplitude. Possible similarities and dissimilarities with two-dimensional instabilities in laterally heated square cavities are discussed. Arguments for grid and time step independence of the results are given.

  19. Cerebral mass due to neurocutaneous melanosis: eight years later. (United States)

    Schaffer, J V; McNiff, J M; Bolognia, J L


    Neurocutaneous melanosis (NCM) is associated most commonly with giant congenital melanocytic nevi (CMN), in particular those on the scalp or in a posterior axial location that are accompanied by satellite congenital nevi. It also can occur in patients with multiple medium-sized CMN. In general, the prognosis of those with symptomatic NCM is poor, even in the absence of malignancy, while the prognosis of those with asymptomatic NCM detected via screening varies and is more difficult to predict. Herein we report an asymptomatic patient with a giant CMN and multiple satellite nevi who had a screening magnetic resonance imaging (MRI) study at age 5 months that showed a rounded area of increased signal in the right temporal lobe on T1-weighted images, suggestive of parenchymal melanosis. This melanotic mass was resected at age 10 months, and histologic examination of the surgical specimen showed prominent perivascular collections of benign, pigment-containing melanocytes within cerebral tissue. The patient remains healthy 8 years later. His excellent long-term outcome and other reports of NCM with localized central nervous system (CNS) involvement apparent on MRI may have implications for management, including early imaging of patients with high-risk CMN and potential surgical intervention for NCM.

  20. Extensor Tendon Instability Due to Sagittal Band Injury in a Martial Arts Athlete: A Case Report. (United States)

    Kochevar, Andrew; Rayan, Ghazi


    A Taekwondo participant sustained a hand injury from punching an opponent that resulted in painful instability of the ring finger extensor digitorum communis tendon due to sagittal band damage. His symptoms resolved after reconstructive surgery on the sagittal band (SB) with stabilization of the extensor tendon over the metacarpophalangeal joint.

  1. Amplification of Weibel instability in the relativistic beam-plasma interactions due to ion streaming (United States)

    Ardaneh, Kazem; Cai, DongSheng; Nishikawa, Ken-Ichi


    On the basis of a three-dimensional relativistic electromagnetic particle-in-cell (PIC) code, we have analyzed the Weibel instability driven by a relativistic electron-ion beam propagating into an unmagnetized ambient electron-ion plasma. The analysis is focused on the ion contribution in the instability, considering the earliest evolution in shock formation. Simulation results demonstrate that the Weibel instability is responsible for generating and amplifying the small-scale, fluctuating, and dominantly transversal magnetic fields. These magnetic fields deflect particles behind the beam front both perpendicular and parallel to the beam propagation direction. Initially, the incoming electrons respond to field fluctuations growing as the result of the Weibel instability. Therefore, the electron current filaments are generated and the total magnetic energy grows linearly due to the mutual attraction between the filaments, and downstream advection of the magnetic field perturbations. When the magnetic fields become strong enough to deflect the much heavier ions, the ions begin to get involved in the instability. Subsequently, the linear growth of total magnetic energy decreases because of opposite electron-ion currents and topological change in the structure of magnetic fields. The ion current filaments are then merged and magnetic field energy grows more slowly at the expense of the energy stored in ion stream. It has been clearly illustrated that the ion current filaments extend through a larger scale in the longitudinal direction, while extension of the electron filaments is limited. Hence, the ions form current filaments that are the sources of deeply penetrating magnetic fields. The results also reveal that the Weibel instability is further amplified due to the ions streaming, but on a longer time scale. Our simulation predictions are in valid agreement with those reported in the literature.

  2. Lateral Decubitus All-Arthroscopic Latarjet Procedure for Treatment of Shoulder Instability. (United States)

    Lewington, Matthew R; Urquhart, Nathan; Wong, Ivan H


    Shoulder instability can be a challenging condition to treat when it becomes refractory to soft-tissue procedures or when bone loss exceeds 25% to 27% of the glenoid. The Bristow-Latarjet procedure has been developed and popularized to deal with these concerns. Traditionally, the procedure has been performed as an open approach; however, this has been recently supplanted by novel arthroscopic techniques. We present a technique for the procedure performed with the patient in a semi-lateral decubitus position that assists with optimal graft placement on the native glenoid. We use the cannulated Bristow-Latarjet Instability Shoulder System (DePuy Mitek, Raynham, MA). After a diagnostic arthroscopic evaluation, we use multiple arthroscopic anterior portals to debride the rim of the glenoid. The coracoid is prepared and taken down arthroscopically, and the cannulated guide is attached and advanced through an arthroscopically created subscapularis split. With the shoulder held in a reduced position, we are then able to drill and anchor the graft to the native glenoid. The patient is able to begin gentle range-of-motion exercises immediately postoperatively.

  3. Lateral Decubitus All-Arthroscopic Latarjet Procedure for Treatment of Shoulder Instability (United States)

    Lewington, Matthew R.; Urquhart, Nathan; Wong, Ivan H.


    Shoulder instability can be a challenging condition to treat when it becomes refractory to soft-tissue procedures or when bone loss exceeds 25% to 27% of the glenoid. The Bristow-Latarjet procedure has been developed and popularized to deal with these concerns. Traditionally, the procedure has been performed as an open approach; however, this has been recently supplanted by novel arthroscopic techniques. We present a technique for the procedure performed with the patient in a semi-lateral decubitus position that assists with optimal graft placement on the native glenoid. We use the cannulated Bristow-Latarjet Instability Shoulder System (DePuy Mitek, Raynham, MA). After a diagnostic arthroscopic evaluation, we use multiple arthroscopic anterior portals to debride the rim of the glenoid. The coracoid is prepared and taken down arthroscopically, and the cannulated guide is attached and advanced through an arthroscopically created subscapularis split. With the shoulder held in a reduced position, we are then able to drill and anchor the graft to the native glenoid. The patient is able to begin gentle range-of-motion exercises immediately postoperatively. PMID:26258032

  4. Nonlinearity management of photonic composites and observation of spatial-modulation instability due to quintic nonlinearity

    CERN Document Server

    Reyna, Albert S


    We present a procedure for nonlinearity management of metal-dielectric composites. Varying the volume fraction occupied by silver nanoparticles suspended in acetone we could cancel the refractive index related to the third-order susceptibility, $\\chi_{eff}^{(3)}$, and the nonlinear refraction behavior was due to the fifth-order susceptibility, $\\chi_{eff}^{(5)}$. Hence, in a cross-phase modulation experiment, we demonstrated for the first time the effect of spatial-modulation- instability due to $\\chi_{eff}^{(5)}$. The results are corroborated with numerical calculations based on a generalized Maxwell-Garnet model.

  5. Enhancement in the electromagnetic beam-plasma instability due to ion streaming (United States)

    Shukla, Nitin; Stockem, A.; Fiúza, F.; Silva, L. O.


    We investigate the Weibel instability in counter-propagating electron-ion plasmas with focus on the ion contribution, considering a realistic mass ratio. A generalized dispersion relation is derived from the relativistic theory by assuming an initially anisotropic temperature, which is represented by a waterbag distribution in momentum space, which shows an enhanced growth rate due to ion response. Two-dimensional particle-in-cell simulations support the theoretical analysis, showing a further amplification of magnetic field on ion time scale. The effect of an initial anisotropic temperature is investigated showing that the growth rate is monotonously decreased if the transverse spread is increased. Nevertheless, the presence of ions generates that the instability can develop for significantly higher electron temperatures. Suppression of oblique mode is also explored by introducing a parallel velocity spread.

  6. Treatment of chronic lateral ankle instability: a modified broström technique using three suture anchors

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    Busconi Brian D


    Full Text Available Abstract Ankle sprains are very common injuries seen in the athletic and young population. Majority of patients will improve with a course of rest and physical therapy. However, with conservative management about twenty percent of all patients will go on to develop chronic lateral ankle instability. This manuscript describes our detailed surgical technique of a modification to the original Broström procedure using three suture anchors to anatomically reconstruct the lateral ankle ligaments to treat high demand patients who have developed chronic lateral ankle instability. The rationale for this modification along with patient selection and workup are discussed. Both the functional outcomes at the two year follow up along with the complications and the detailed postoperative rehabilitation protocol for the high demand athletes are also presented. This modified Broström procedure is shown in both illustrative format and intra-operative photos.

  7. A probabilistic decomposition-synthesis method for the quantification of rare events due to internal instabilities (United States)

    Mohamad, Mustafa A.; Cousins, Will; Sapsis, Themistoklis P.


    We consider the problem of the probabilistic quantification of dynamical systems that have heavy-tailed characteristics. These heavy-tailed features are associated with rare transient responses due to the occurrence of internal instabilities. Systems with these properties can be found in a variety of areas including mechanics, fluids, and waves. Here we develop a computational method, a probabilistic decomposition-synthesis technique, that takes into account the nature of internal instabilities to inexpensively determine the non-Gaussian probability density function for any arbitrary quantity of interest. Our approach relies on the decomposition of the statistics into a 'non-extreme core', typically Gaussian, and a heavy-tailed component. This decomposition is in full correspondence with a partition of the phase space into a 'stable' region where we have no internal instabilities, and a region where non-linear instabilities lead to rare transitions with high probability. We quantify the statistics in the stable region using a Gaussian approximation approach, while the non-Gaussian distribution associated with the intermittently unstable regions of phase space is inexpensively computed through order-reduction methods that take into account the strongly nonlinear character of the dynamics. The probabilistic information in the two domains is analytically synthesized through a total probability argument. The proposed approach allows for the accurate quantification of non-Gaussian tails at more than 10 standard deviations, at a fraction of the cost associated with the direct Monte-Carlo simulations. We demonstrate the probabilistic decomposition-synthesis method for rare events for two dynamical systems exhibiting extreme events: a two-degree-of-freedom system of nonlinearly coupled oscillators, and in a nonlinear envelope equation characterizing the propagation of unidirectional water waves.

  8. Latarjet Procedure for Anterior Shoulder Instability Due to Tramadol-Induced Seizures: A Multicenter Study. (United States)

    Khater, Ahmad Hany; Sobhy, Mohamed H; Said, Hatem G; Kandil, Ahmed; Reda, Walid; Seifeldin, Ahmed Fouad; Moustafa, Ramez; Elassal, Maher A; Kamel, Ezzat M


    Seizures, commonly due to epilepsy, are known to cause shoulder instability. Tramadol addiction has recently been found to induce seizures in patients who exceed the recommended dose. Because of the easy accessibility and low cost of tramadol, an increasingly alarming phenomenon of tramadol abuse has been demonstrated in recent years. The purpose of this multicenter study was to investigate shoulder instability resulting from tramadol-induced seizure (TIS) as well as to recommended management for such shoulder instability. The hypothesis was that TIS leads to anterior shoulder dislocations with major bony defects, which favors bony reconstructive procedures as a suitable method of treatment. Case series; Level of evidence, 4. This prospective case series study was conducted on 73 patients (78 shoulders) who presented with anterior shoulder dislocations and a clear history of tramadol abuse. The mean age of the patients was 26.8 years, and the mean number of dislocations was 14. The mean duration of addiction was 17 months, with a mean dose of 752 mg of tramadol hydrochloride per day. Glenoid and humeral bone loss ranged from 15% to 35% and from 15% to 40%, respectively. The mean follow-up period was 28 months. All patients underwent an open Latarjet procedure. Postoperative mean Rowe score and American Shoulder and Elbow Surgeons score at final follow-up (24 months) improved significantly from 20 to 84 and from 44 to 91, respectively (P Latarjet procedure is recommended for these patients, after control of addiction, and provides 95% satisfaction at midterm follow-up. © 2016 The Author(s).

  9. Methylene Blue Is Effective to Reverse Refractory Hemodynamic Instability due to Dimethoate Poisoning

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    Nick Youssefi


    Conclusion:MB treatment was effective to reverse hypotension and restore hemodynamic instability caused by dimethoate poisoning. This index case may pave way to further investigation of MB therapy for OP-induced hemodynamic instabilities.

  10. Fractal flame structure due to the hydrodynamic Darrieus-Landau instability (United States)

    Yu, Rixin; Bai, Xue-Song; Bychkov, Vitaly


    By using large scale numerical simulations, we obtain fractal structure, which develops at originally planar flame fronts due to the hydrodynamic Darrieus-Landau (DL) instability bending the fronts. We clarify some important issues regarding the DL fractal flames, which have been debated for a long time. We demonstrate an increase of the flame propagation speed with the hypothetic channel width, which controls the length scale of the instability development. We show that this increase may be fitted by a power law indicating the mean fractal properties of the flame front structure. The power exponent in this law is found to be not a universal constant, rather it depends on the flame properties—on the density drop at the front. Using box counting on the simulated flame front shapes we show the fractal flame dimension at the intermediate scale is smaller than the one given by the power law, but it has a similar dependency on the density drop. We also obtain a formation of pockets at the DL fractal flame fronts, which previously has been associated only with turbulent burning.

  11. Ring Structure Formation in Protoplanetary Disks due to the Two-Fluid Secular Gravitational Instability: An Indicator of Dust Concentration

    CERN Document Server

    Takahashi, Sanemichi Z


    The instability in protoplanetary disks due to gas-dust friction and self-gravity of gas and dust is investigated by linear analysis. For conditions typical of protoplanetaly disks, the instability grows, even in gravitationally stable disks, on a timescale of order $10^{4-5}$yr at a radius of order 100AU. If we ignore the dynamical feedback from dust grains in the gas equation of motion, the instability reduces to the so-called "secular gravitational instability", that was investigated previously as the instability of dust in a fixed background gas flow. In this work, we solve the equation of motion for both gas and dust consistently and find that long-wavelength perturbations are stable, in contrast to the secular gravitational instability in the simplified treatment. The instability is expected to form ring structures in protoplanetary disks. The width of the ring formed at a radius of 100 AU is a few tens of AU. Therefore, the instability is a candidate for the formation mechanism of observed ring-like st...

  12. Parallel numerical simulation of oscillating airfoil NACA0015 in the channel due to flutter instability

    Directory of Open Access Journals (Sweden)

    Řidký Václav


    Full Text Available The work is devoted to 3D and 2D parallel numerical computation of pressure and velocity fields around an elastically supported airfoil self-oscillating due to interaction with the airflow. Numerical solution is computed in the OpenFOAM package, an open-source software package based on finite volume method. Movement of airfoil is described by translation and rotation, identified from experimental data. A new boundary condition for the 2DOF motion of the airfoil was implemented. The results of numerical simulations (velocity are compared with data measured in a wind tunnel, where a physical model of NACA0015 airfoil was mounted and tuned to exhibit the flutter instability. The experimental results were obtained previously in the Institute of Thermomechanics by interferographic measurements in a subsonic wind tunnel in Nový Knín.

  13. Gravitational instability due to the dissolution of carbon dioxide in a Hele-Shaw cell (United States)

    Vreme, A.; Nadal, F.; Pouligny, B.; Jeandet, P.; Liger-Belair, G.; Meunier, P.


    We present an experimental study of the gravitational instability triggered by dissolution of carbon dioxide through a water-gas interface. We restrict the study to vertical parallelepipedic Hele-Shaw geometries, for which the thickness is smaller than the other dimensions. The partial pressure of carbon dioxide is quickly increased, leading to a denser layer of CO2-enriched water underneath the surface. This initially one-dimensional diffusive layer destabilizes through a convection-diffusion process. The concentration field of carbon dioxide, which is visualized by means of a pH-sensitive dye, shows a fingering pattern whose characteristics (wavelength and amplitude growth rate) are functions of the Rayleigh (Ra) and the Darcy (Da) numbers. At low Rayleigh numbers, the growth rate and the wave numbers are independent of the Rayleigh number and in excellent agreement with the classical results obtained numerically and theoretically in the Darcy regime. However, above a threshold of Ra√{Da} of the order of 10, the growth rate and the wave number strongly decrease due to the Brinkman term associated with the viscous diffusion in the vertical and longitudinal directions. In this Darcy-Brinkman regime, the growth rate and the wave number depend only on the thickness-based Rayleigh number Ra√{Da} . The classical Rayleigh-Taylor theory including the Brinkman term has been extended to this diffusive gravitational instability and gives an excellent prediction of the growth rate over four decades of Rayleigh numbers. However, the Brinkman regime seems to be valid only until Ra√{Da}=1000 . Above this threshold, the transverse velocity profile is no longer parabolic, which leads to an overestimation of the wave number by the theory.

  14. Sound generation and upstream influence due to instability waves interacting with non-uniform mean flows (United States)

    Goldstein, M. E.


    Attention is given to the sound produced by artificially excited, spatially growing instability waves on subsonic shear layers. Real flows that always diverge in the downstream direction allow sound to be produced by the interaction of the instability waves with the resulting streamwise variations of the flow. The upstream influence, or feedback, can interact with the splitter plate lip to produce a downstream-propagating instability wave that may under certain conditions be the same instability wave that originally generated the upstream influence. The present treatment is restricted to very low Mach number flows, so that compressibility effects can only become important over large distances.

  15. Reliability of forced internal rotation and active internal rotation to assess lateral instability of the biceps pulley (United States)



    Purpose the aim of this study was to investigate the relationship between positive painful forced internal rotation (FIR) and lateral pulley instability in the presence of a pre-diagnosed posterosuperior cuff tear. The same investigation was conducted for painful active internal rotation (AIR). Methods a multicenter prospective study was conducted in a series of patients scheduled to undergo arthroscopic posterosuperior cuff repair. Pain was assessed using a visual analog scale (VAS) and the Disabilities of the Arm, Shoulder and Hand questionnaire (DASH) was administered. The VAS score at rest, DASH score, and presence/absence of pain on FIR and AIR were recorded and their relationships with lesions of the lateral pulley, cuff tear patterns and shape of lesions were analyzed. Results the study population consisted of 115 patients (mean age: 55.1 years) recruited from 12 centers. The dominant arm was affected in 72 cases (62.6%). The average anteroposterior extension of the lesion was 1.61 cm. The mean preoperative VAS and DASH scores were 6.1 and 41.8, respectively. FIR and AIR were positive in 94 (81.7%) and 85 (73.9%) cases, respectively. The lateral pulley was compromised in 50 cases (43.4%). Cuff tears were partial articular in 35 patients (30.4%), complete in 61 (53%), and partial bursal in 19 (16.5%). No statistical correlation between positive FIR or AIR and lateral pulley lesions was detected. Positive FIR and AIR were statistically associated with complete lesions. Negative FIR was associated with the presence of partial articular tears. Conclusions painful FIR in the presence of a postero-superior cuff tear does not indicate lateral pulley instability. When a cuff tear is suspected, positive FIR and AIR are suggestive of full-thickness tear patterns while a negative FIR suggests a partial articular lesion. Level of evidence: level I, validating cohort study with good reference standards. PMID:26151035

  16. Numerical instability due to relativistic plasma drift in EM-PIC simulations

    CERN Document Server

    Xu, Xinlu; Martins, Samual F; Tsung, Frank S; Decyk, Viktor K; Fonseca, Ricardo A; Lu, Wei; Silva, Luis O; Mori, Warren B


    The numerical instability observed in the Electromagnetic-Particle-in-cell (EM-PIC) simulations with a plasma drifting with relativistic velocities is studied using both theory and computer simulations. We derive the numerical dispersion relation for a cold plasma drifting with a relativistic velocity and find an instability attributed to the coupling between the beam modes of the drifting plasma and the electromagnetic modes in the system. The characteristic pattern of the instability in Fourier space for various simulation setups and Maxwell Equation solvers are explored by solving the corresponding numerical dispersion relations. Furthermore, based upon these characteristic patterns we derive an asymptotic expression for the instability growth rate. The results are compared against simulation results and good agreement is found. The results are used as a guide to develop possible approaches to mitigate the instability. We examine the use of a spectral solver and show that such a solver when combined with a...

  17. Electrostatic electron cyclotron instabilities near the upper hybrid layer due to electron ring distributions (United States)

    Eliasson, B.; Speirs, D. C.; Daldorff, L. K. S.


    A theoretical study is presented of the electrostatic electron cyclotron instability involving Bernstein modes in a magnetized plasma. The presence of a tenuous thermal ring distribution in a Maxwellian plasma decreases the frequency of the upper hybrid branch of the electron Bernstein mode until it merges with the nearest lower branch with a resulting instability. The instability occurs when the upper hybrid frequency is somewhat above the third, fourth, and higher electron cyclotron harmonics, and gives rise to a narrow spectrum of waves around the electron cyclotron harmonic nearest to the upper hybrid frequency. For a tenuous cold ring distribution together with a Maxwellian distribution an instability can take place also near the second electron cyclotron harmonic. Noise-free Vlasov simulations are used to assess the theoretical linear growth-rates and frequency spectra, and to study the nonlinear evolution of the instability. The relevance of the results to laboratory and ionospheric heating experiments is discussed.

  18. Buoyancy Instabilities in Galaxy Clusters: Convection Due to Adiabatic Cosmic Rays and Anisotropic Thermal Conduction

    CERN Document Server

    Sharma, P; Quataert, E; Parrish, I J


    Using a linear stability analysis and two and three-dimensional nonlinear simulations, we study the physics of buoyancy instabilities in a combined thermal and relativistic (cosmic ray) plasma, motivated by the application to clusters of galaxies. We argue that cosmic ray diffusion is likely to be slow compared to the buoyancy time on large length scales, so that cosmic rays are effectively adiabatic. If the cosmic ray pressure $p_{cr}$ is $\\gtrsim 25 %$ of the thermal pressure, and the cosmic ray entropy ($p_{\\rm cr}/\\rho^{4/3}$; $\\rho$ is the thermal plasma density) decreases outwards, cosmic rays drive an adiabatic convective instability analogous to Schwarzschild convection in stars. Global simulations of galaxy cluster cores show that this instability saturates by reducing the cosmic ray entropy gradient and driving efficient convection and turbulent mixing. At larger radii in cluster cores, the thermal plasma is unstable to the heat flux-driven buoyancy instability (HBI), a convective instability genera...

  19. Dynamic instability of cooperation due to diverse activity patterns in evolutionary social dilemmas (United States)

    Xia, Cheng-Yi; Meloni, Sandro; Perc, Matjaž; Moreno, Yamir


    Individuals might abstain from participating in an instance of an evolutionary game for various reasons, ranging from lack of interest to risk aversion. In order to understand the consequences of such diverse activity patterns on the evolution of cooperation, we study a weak prisoner's dilemma where each player's participation is probabilistic rather than certain. Players that do not participate get a null payoff and are unable to replicate. We show that inactivity introduces cascading failures of cooperation, which are particularly severe on scale-free networks with frequently inactive hubs. The drops in the fraction of cooperators are sudden, while the spatiotemporal reorganization of compact cooperative clusters, and thus the recovery, takes time. Nevertheless, if the activity of players is directly proportional to their degree, or if the interaction network is not strongly heterogeneous, the overall evolution of cooperation is not impaired. This is because inactivity negatively affects the potency of low-degree defectors, who are hence unable to utilize on their inherent evolutionary advantage. Between cascading failures, the fraction of cooperators is therefore higher than usual, which lastly balances out the asymmetric dynamic instabilities that emerge due to intermittent blackouts of cooperative hubs.

  20. Energetics of lateral eddy diffusion/advection:Part II. Numerical diffusion/diffusivity and gravitational potential energy change due to isopycnal diffusion

    Institute of Scientific and Technical Information of China (English)

    HUANG Rui Xin


    Study of oceanic circulation and climate requires models which can simulate tracer eddy diffusion and ad-vection accurately. It is shown that the traditional Eulerian coordinates can introduce large artificial hori-zontal diffusivity/viscosity due to the incorrect alignment of the axis. Therefore, such models can smear sharp fronts and introduce other numerical artifacts. For simulation with relatively low resolution, large lateral diffusion was explicitly used in models;therefore, such numerical diffusion may not be a problem. However, with the increase of horizontal resolution, the artificial diffusivity/viscosity associated with hori-zontal advection in the commonly used Eulerian coordinates may become one of the most challenging ob-stacles for modeling the ocean circulation accurately. Isopycnal eddy diffusion (mixing) has been widely used in numerical models. The common wisdom is that mixing along isopycnal is energy free. However, a careful examination reveals that this is not the case. In fact, eddy diffusion can be conceptually separated into two steps:stirring and subscale diffusion. Due to the thermobaric effect, stirring, or exchanging water masses, along isopycnal surface is associated with the change of GPE in the mean state. This is a new type of instability, called the thermobaric instability. In addition, due to cabbeling subscale diffusion of water parcels always leads to the release of GPE. The release of GPE due to isopycnal stirring and subscale diffusion may lead to the thermobaric instability.

  1. Pattern formation by temperature-gradient driven film instabilities in laterally confined geometries

    NARCIS (Netherlands)

    Nedelcu, M; Morariu, MD; Harkema, S; Voicu, NE; Steiner, U


    Film break-up driven by an electric field or temperature gradient typically exhibit a characteristic length scale. The presence of a lateral confinement significantly alters this pattern formation process.

  2. Evidence of locally enhanced target heating due to instabilities of counter-streaming fast electron beams

    Energy Technology Data Exchange (ETDEWEB)

    Koester, Petra; Cecchetti, Carlo A. [Intense Laser Irradiation Laboratory at INO, CNR, Pisa (Italy); Booth, Nicola; Woolsey, Nigel [Physics Department, University of York, York (United Kingdom); Chen, Hui [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Evans, Roger G. [Imperial College London, London (United Kingdom); Gregori, Gianluca; Li, Bin; Mithen, James; Murphy, Christopher D. [Physics Department, University of Oxford, Oxford (United Kingdom); Labate, Luca; Gizzi, Leonida A. [Intense Laser Irradiation Laboratory at INO, CNR, Pisa (Italy); INFN, Sezione di Pisa, Pisa (Italy); Levato, Tadzio [Intense Laser Irradiation Laboratory at INO, CNR, Pisa (Italy); University of Rome Tor Vergata, Rome (Italy); Makita, Mikako; Riley, David [Physics Department, Queens University Belfast, Belfast (United Kingdom); Notley, Margaret; Pattathil, Rajeev [Rutherford Appleton Laboratory, STFC, Didcot (United Kingdom)


    The high-current fast electron beams generated in high-intensity laser-solid interactions require the onset of a balancing return current in order to propagate in the target material. Such a system of counter-streaming electron currents is unstable to a variety of instabilities such as the current-filamentation instability and the two-stream instability. An experimental study aimed at investigating the role of instabilities in a system of symmetrical counter-propagating fast electron beams is presented here for the first time. The fast electron beams are generated by double-sided laser-irradiation of a layered target foil at laser intensities above 10{sup 19 }W/cm{sup 2}. High-resolution X-ray spectroscopy of the emission from the central Ti layer shows that locally enhanced energy deposition is indeed achieved in the case of counter-propagating fast electron beams.

  3. Stationary Crossflow Breakdown due to Mixed Mode Spectra of Secondary Instabilities (United States)

    Li, Fei; Choudhari, Meelan M.; Duan, Lian


    Numerical simulations are used to study laminar breakdown characteristics associated with stationary crossflow instability in the boundary-layer flow over a subsonic swept-wing configuration. Previous work involving the linear and nonlinear development of individual, fundamental modes of secondary instability waves is extended by considering the role of more complex, yet controlled, spectra of the secondary instability modes. Direct numerical simulations target a mixed mode transition scenario involving the simultaneous presence of Y and Z modes of secondary instability. For the initial amplitudes investigated in this paper, the Y modes are found to play an insignificant role during the onset of transition, in spite of achieving rather large, O(5%), amplitudes of RMS velocity fluctuation prior to transition. Analysis of the numerical simulations shows that this rather surprising finding can be attributed to the fact that the Y modes are concentrated near the top of the crossflow vortex and exert relatively small influence on the Z modes that reside closer to the surface and can lead to transition via nonlinear spreading that does not involve interactions with the Y mode. Finally, secondary instability calculations reveal that subharmonic modes of secondary instability have substantially lower growth rates than those of the fundamental modes, and hence, are less likely to play an important role during the breakdown process involving complex initial spectra.

  4. Numerical instability due to relativistic plasma drift in EM-PIC simulations (United States)

    Xu, Xinlu; Yu, Peicheng; Martins, Samual F.; Tsung, Frank S.; Decyk, Viktor K.; Vieira, Jorge; Fonseca, Ricardo A.; Lu, Wei; Silva, Luis O.; Mori, Warren B.


    The numerical instability observed in electromagnetic particle-in-cell (EM-PIC) simulations with a plasma drifting with relativistic velocities is studied using both theory and computer simulations. We derive the numerical dispersion relation for a cold plasma drifting with a relativistic velocity, and find an instability attributed to the intersection between beam resonances and the electromagnetic modes in the drifting plasma. The intersection can occur in the fundamental Brillouin zones when EM waves with phase velocities less than the speed of light exist, and from aliasing beam resonances and aliasing EM modes. The unstable modes are neither purely transverse nor longitudinal. The characteristic patterns of the instability in Fourier space for various simulation setups and Maxwell equation solvers are explored by solving the corresponding numerical dispersion relations. Furthermore, based upon these characteristic patterns, we derive an asymptotic expression for the instability growth rate. The asymptotic expression greatly speeds up the calculation of the instability growth rate and makes the parameter scans for minimal growth rate feasible even for full three dimensions. The results are compared against simulation results, and good agreements are found. These results can be used as a guide to develop possible approaches to mitigate the instability. We examine the use of a spectral solver and show that such a solver when combined with a low pass filter with a cutoff value of |k→| essentially eliminates the instability while not modifying modes of physical interest. The use of a spectral solver also provides minimal errors to electromagnetic modes in the lowest Brillouin zones.

  5. Late diagnosis of lateral meningocele syndrome in a 55-year-old woman with symptoms of joint instability and chronic musculoskeletal pain. (United States)

    Castori, Marco; Morlino, Silvia; Ritelli, Marco; Brancati, Francesco; De Bernardo, Carmelilia; Colombi, Marina; Grammatico, Paola


    Lateral meningocele syndrome (LMS) is a rare hereditary connective tissue disorder characterized by pan-spinal meningoceles, specific facial dysmorphism, skeletal and soft tissue abnormalities, and hypotonia and/or muscle weakness. LMS has been observed in eleven patients with two instances of vertical transmission, and seven sporadic cases with an age at diagnosis ranging from 25 months to 33 years. We report on a further observation of LMS in a 55-year-old woman presenting with a long history of joint instability, chronic musculoskeletal pain, and iatrogenic bladder and anorectal dysfunction due to irreversible nerve damage after surgical excision of a meningeal cyst. Her clinical characteristics are compared with those of previously reported patients, as well as two further cases originally diagnosed with Hajdu-Cheney and Ehlers-Danlos syndromes, but displaying typical features of LMS.

  6. Rayleigh-Taylor Instability within Sediment Layers Due to Gas Retention: Preliminary Theory and Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Gauglitz, Phillip A.; Wells, Beric E.; Buchmiller, William C.; Rassat, Scot D.


    In Hanford underground waste storage tanks, a typical waste configuration is settled beds of waste particles beneath liquid layers. The settled beds are typically composed of layers, and these layers can have different physical and chemical properties. One postulated configuration within the settled bed is a less-dense layer beneath a more-dense layer. The different densities can be a result of different gas retention in the layers or different degrees of settling and compaction in the layers. This configuration can experience a Rayleigh-Taylor (RT) instability where the less dense lower layer rises into the upper layer. Previous studies of gas retention and release have not considered potential buoyant motion within a settle bed of solids. The purpose of this report is to provide a review of RT instabilities, discuss predictions of RT behavior for sediment layers, and summarize preliminary experimental observations of RT instabilities in simulant experiments.

  7. Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival.

    Directory of Open Access Journals (Sweden)

    Qi Wang


    Full Text Available The nature of the "toxic gain of function" that results from amyotrophic lateral sclerosis (ALS-, Parkinson-, and Alzheimer-related mutations is a matter of debate. As a result no adequate model of any neurodegenerative disease etiology exists. We demonstrate that two synergistic properties, namely, increased protein aggregation propensity (increased likelihood that an unfolded protein will aggregate and decreased protein stability (increased likelihood that a protein will unfold, are central to ALS etiology. Taken together these properties account for 69% of the variability in mutant Cu/Zn-superoxide-dismutase-linked familial ALS patient survival times. Aggregation is a concentration-dependent process, and spinal cord motor neurons have higher concentrations of Cu/Zn-superoxide dismutase than the surrounding cells. Protein aggregation therefore is expected to contribute to the selective vulnerability of motor neurons in familial ALS.

  8. Temperature Isotropization in Solar Flare Plasmas due to the Electron Firehose Instability

    CERN Document Server

    Messmer, P


    The isotropization process of a collisionless plasma with an electron temperature anisotropy along an external magnetic field ($T_\\| ^e\\gg T_\\perp^e$, $\\|$ and $\\perp$ with respect to the background magnetic field) and isotropic protons is investigated using a particle-in-cell(PIC) code. Restricting wave growth mainly parallel to the external magnetic field, the isotropization mechanism is identified to be the Electron Firehose Instability (EFI). The free energy in the electrons is first transformed into left-hand circularly polarized transverse low-frequency waves by a non-resonant interaction. Fast electrons can then be scattered towards higher perpendicular velocities by gyroresonance, leading finally to a complete isotropization of the velocity distribution. During this phase of the instability, Langmuir waves are generated which may lead to the emission of radio waves. A large fraction of the protons is resonant with the left-hand polarized electromagnetic waves, creating a proton temperature anisotropy ...

  9. Acceleration of raindrops formation due to tangling-clustering instability in turbulent stratified atmosphere

    CERN Document Server

    Elperin, T; Krasovitov, B; Kulmala, M; Liberman, M; Rogachevskii, I; Zilitinkevich, S


    Condensation of water vapor on active cloud condensation nuclei produces micron-size water droplets. To form rain, they must grow rapidly into at least 50-100 micron-size droplets. Observations show that this process takes only 15-20 minutes. The unexplained physical mechanism of such fast growth, is crucial for understanding and modeling of rain, and known as "condensation-coalescence bottleneck in rain formation". We show that the recently discovered phenomenon of the tangling clustering instability of small droplets in temperature-stratified turbulence (Phys. Fluids 25, 085104, 2013) results in the formation of droplet clusters with drastically increased droplet number densities and strong five-orders-of-magnitude enhancement of the collision-coalescence rate inside the clusters. The mechanism of tangling clustering instability in the temperature-stratified turbulence is much more effective than the previously considered pure inertial clustering caused by the centrifugal effect of turbulent vortices. Our a...

  10. Filamentation due to the Weibel Instability in two counterstreaming laser ablated plasmas (United States)

    Dong, Quan-Li; Yuan, Dawei; Gao, Lan; Liu, Xun; Chen, Yangao; Jia, Qing; Hua, Neng; Qiao, Zhanfeng; Chen, Ming; Zhu, Baoqiang; Zhu, Jianqiang; Zhao, Gang; Ji, Hantao; Sheng, Zheng-Ming; Zhang, Jie


    Weibel-type filamentation instability was observed in the interaction of two counter streaming laser ablated plasma flows, which were supersonic, collisionless, and closely relevant to astrophysical conditions. The plasma flows were created by irradiating a pair of oppositely standing plastic (CH) foils with 1ns-pulsed laser beams of total energy of 1.7 kJ in two laser spots. With characteristics diagnosed in experiments, the calculated features of Weibel-type filaments are in good agreement with measurements.

  11. Thermocapillary instabilities in a laterally heated liquid bridge with end wall rotation (United States)

    Kahouadji, L.; Houchens, B. C.; Witkowski, L. Martin


    The effect of rotation on the stability of thermocapillary driven flow in a laterally heated liquid bridge is studied numerically using the full-zone model of the floating-zone crystal growth technique. A small Prandtl number (0.02) fluid, relevant for semiconductor melts, is studied with an aspect ratio (height to diameter of the melt) equal to one. Buoyancy is neglected. A linear stability analysis of three-dimensional perturbations is performed and shows that for any ratio of angular velocities, a weak rotation rate has the surprising effect of destabilizing the base flow. By systematically varying the rotation rate and ratio of angular velocities, the critical threshold and azimuthal wave number of the most unstable mode is found over a wide range of this two parameter space. Depending on these parameters, the leading eigenmode is a wave propagating either in the positive or negative azimuthal direction, with kinetic energy typically localized close to one of the end walls. These results are of practical interest for industrial crystal growth applications, where rotation is often used to obtain higher quality crystals.

  12. Thermocapillary instabilities with crystal and feed rod rotation in laterally heated liquid bridge (United States)

    Witkowski, Laurent Martin; Kahouadji, Lyes; Walker, John S.


    Rotation is involved in many industrial processes for crystal growth. The main reason is that heating is usually not uniform in the azimuthal direction. A drawback (or advantage) of rotation is that it modifies the flow originating from thermal or electromagnetic sources. In the needle-eye float-zone process, the optimum angular velocity of the feed rod and crystal is found empirically. The ratio of these velocities is often negative but not always. Early numerical studies focused on the baseflow of the melt and were restricted to axisymmetry. The main finding is that when rotation is large enough the flow is confined toward the periphery as a result of Taylor column effect. More recent research is devoted to the stability of thermocapillary convection to tridimensional disturbances either by direct numerical simulations or by linear analysis but few relate to the effect of rotation. In order to have a better understanding of the effect of rotation rate on the critical Marangoni number for a laterally heated liquid bridge, we have studied the stability of tridimensional perturbation by a linear analysis for various angular velocity ratio. The competition between different azimuthal modes has been explored and some interpretations are given.


    Directory of Open Access Journals (Sweden)

    Petr Vanícek


    Full Text Available Helmert (1890 used Poincaré-Prey's gravity gradient for the definition of the orthometric height. According to this approach the gravity value needed for the evaluation of the height is obtained from the observed gravity at the earth surface reduced to the mid-point between the earth surface and the geoid, considering that the gravity gradient is constant along the plumbline. Moreover, the mean topographical density is assumed to approximate the actual distribution of topographical density. The correction to Helmert's orthometric height due to the lateral variation of topographical density has been introduced by Vanícek et al. (1995. In this paper, some numerical aspects of this correction are investigated.

  14. Nonlinear damping of a finite amplitude whistler wave due to modified two stream instability

    Energy Technology Data Exchange (ETDEWEB)

    Saito, Shinji, E-mail: [Graduate School of Science, Nagoya University, Nagoya (Japan); Solar-Terrestrial Environment Laboratory, Nagoya University, Nagoya (Japan); Nariyuki, Yasuhiro, E-mail: [Faculty of Human Development, University of Toyama, Toyama (Japan); Umeda, Takayuki, E-mail: [Solar-Terrestrial Environment Laboratory, Nagoya University, Nagoya (Japan)


    A two-dimensional, fully kinetic, particle-in-cell simulation is used to investigate the nonlinear development of a parallel propagating finite amplitude whistler wave (parent wave) with a wavelength longer than an ion inertial length. The cross field current of the parent wave generates short-scale whistler waves propagating highly oblique directions to the ambient magnetic field through the modified two-stream instability (MTSI) which scatters electrons and ions parallel and perpendicular to the magnetic field, respectively. The parent wave is largely damped during a time comparable to the wave period. The MTSI-driven damping process is proposed as a cause of nonlinear dissipation of kinetic turbulence in the solar wind.

  15. Luminosity Loss due to Beam Distortion and the Beam-Beam Instability

    CERN Document Server

    Wu, Juhao; Raubenheimer, Tor O; Seryi, Andrei; Sramek, Christopher K


    In a linear collider, sources of emittance dilution such as transverse wakefields or dispersive errors will couple the vertical phase space to the longitudinal position within the beam (the so-called ‘banana effect'). When the Intersection Point (IP) disruption parameter is large, these beam distortions will be amplified by a single bunch kink instability which will lead to luminosity loss. We study this phenomena both analytically using linear theory and via numerical simulation. In particular, we examine the dependence of the luminosity loss on the wavelength of the beam distortions and the disruption parameter. This analysis may prove useful when optimizing the vertical disruption parameter for luminosity operation with given beam distortions.

  16. Undulation instability in a bilayer lipid membrane due to electric field interaction with lipid dipoles

    CERN Document Server

    Bingham, Richard J; Smye, Stephen W


    Bilayer lipid membranes [BLMs] are an essential component of all biological systems, forming a functional barrier for cells and organelles from the surrounding environment. The lipid molecules that form membranes contain both permanent and induced dipoles, and an electric field can induce the formation of pores when the transverse field is sufficiently strong (electroporation). Here, a phenomenological free energy is constructed to model the response of a BLM to a transverse static electric field. The model contains a continuum description of the membrane dipoles and a coupling between the headgroup dipoles and the membrane tilt. The membrane is found to become unstable through buckling modes, which are weakly coupled to thickness fluctuations in the membrane. The thickness fluctuations, along with the increase in interfacial area produced by membrane buckling, increase the probability of localized membrane breakdown, which may lead to pore formation. The instability is found to depend strongly on the strengt...

  17. Quasilinear transport due to the magnetic drift resonance with the ion temperature gradient instability in a rotating plasma (United States)

    Zhang, Debing; Xu, Yingfeng; Wang, Shaojie


    The quasilinear transport fluxes due to the ion temperature gradient instability are calculated in a toroidal plasma, in which the magnetic drift resonance is treated rigorously. The effects of the equilibrium parallel flow and flow shear on the radial particle and heat fluxes are studied numerically in detail. In the radial component of parallel viscosity, there exist the pinches driven by the density gradient, the temperature gradient, and the curvature of the background magnetic field. The direction of these pinches is discussed. It is found that each pinch can be inward or outward, which depends crucially on the resonance condition.

  18. Flow Instabilities in Feather Seals due to Upstream Harmonic Pressure Fluctuations (United States)

    Deng, D.; Braun, M. J.; Henricks, Robert C.


    Feather seals (also called slot seals) typically found in turbine stators limit leakage from the platform into the core cavities and from the shroud to the case. They are of various geometric shapes, yet all are contoured to fit the aerodynamic shape of the stator and placed as close as thermomechanically reasonable the powerstream flow passage. Oscillations engendered in the compressor or combustor alter the steady leakage characteristics of these sealing elements and in some instances generate flow instabilities downstream of the seal interface. In this study, a generic feather seal geometry was studied numerically by imposing an upstream harmonic pressure disturbance on the simulated stator-blade gap. The flow and thermal characteristics were determined; it was found that for high pressure drops, large fluctuations in flows in the downstream blade-stator gap can occur. These leakages and pulsations in themselves are not all that significant, yet if coupled with cavity parameters, they could set up resonance events. Computationally generated time-dependent flow fields are captured in sequence video streaming.

  19. CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability (United States)

    Minegishi, Yuriko; Sheng, XunLun; Yoshitake, Kazutoshi; Sergeev, Yuri; Iejima, Daisuke; Shibagaki, Yoshio; Monma, Norikazu; Ikeo, Kazuho; Furuno, Masaaki; Zhuang, Wenjun; Liu, Yani; Rong, Weining; Hattori, Seisuke; Iwata, Takeshi


    Leber congenital amaurosis (LCA) is a hereditary early-onset retinal dystrophy that is accompanied by severe macular degeneration. In this study, novel compound heterozygous mutations were identified as LCA-causative in chaperonin-containing TCP-1, subunit 2 (CCT2), a gene that encodes the molecular chaperone protein, CCTβ. The zebrafish mutants of CCTβ are known to exhibit the eye phenotype while its mutation and association with human disease have been unknown. The CCT proteins (CCT α-θ) forms ring complex for its chaperon function. The LCA mutants of CCTβ, T400P and R516H, are biochemically instable and the affinity for the adjacent subunit, CCTγ, was affected distinctly in both mutants. The patient-derived induced pluripotent stem cells (iPSCs), carrying these CCTβ mutants, were less proliferative than the control iPSCs. Decreased proliferation under Cct2 knockdown in 661W cells was significantly rescued by wild-type CCTβ expression. However, the expression of T400P and R516H didn’t exhibit the significant effect. In mouse retina, both CCTβ and CCTγ are expressed in the retinal ganglion cells and connecting cilium of photoreceptor cells. The Cct2 knockdown decreased its major client protein, transducing β1 (Gβ1). Here we report the novel LCA mutations in CCTβ and the impact of chaperon disability by these mutations in cellular biology. PMID:27645772

  20. Growth instability due to lattice-induced topological currents in limited-mobility epitaxial growth models. (United States)

    Kanjanaput, Wittawat; Limkumnerd, Surachate; Chatraphorn, Patcha


    The energetically driven Ehrlich-Schwoebel barrier had been generally accepted as the primary cause of the growth instability in the form of quasiregular moundlike structures observed on the surface of thin film grown via molecular-beam epitaxy (MBE) technique. Recently the second mechanism of mound formation was proposed in terms of a topologically induced flux of particles originating from the line tension of the step edges which form the contour lines around a mound. Through large-scale simulations of MBE growth on a variety of crystalline lattice planes using limited-mobility, solid-on-solid models introduced by Wolf-Villain and Das Sarma-Tamborenea in 2+1 dimensions, we show that there exists a topological uphill particle current with strong dependence on specific lattice crystalline structure. Without any energetically induced barriers, our simulations produce spectacular mounds very similar, in some cases, to what have been observed in many recent MBE experiments. On a lattice where these currents cease to exist, the surface appears to be scale invariant, statistically rough as predicted by the conventional continuum growth equation.

  1. A coupled bunch instability due to beam-photoelectron interactions in KEKB-LER

    Energy Technology Data Exchange (ETDEWEB)

    Ohmi, Kazuhito [National Lab. for High Energy Physics, Tsukuba, Ibaraki (Japan)


    LER of KEKB is designed to storage the positron beam of 2.6 A with multibunch operation. Nb = 3.3 x 10{sup 10} positrons are filled in a bunch and the bunch passes every 2ns through a beam chamber. The photoelectron instability may be serious for KEKB-LER. We consider a motion of photoelectrons produced by a bunch with a computer simulation technic. A cylindrical chamber with a diameter of 10 cm was used as a model chamber. About 15 times of the photoelectrons were produced by a bunch. The wake force was calculated for the loading bunches with displacements of 0.5 mm and 1 mm. The wake characteristics seems to be caused by the trapped electrons kicked by the loading bunch. The wake was saturated with the loading displacement of 0.5 mm. We obtained a growth rate by the wake force. It is very high rate, 2500s{sup -1} which exceeds damping rates of various mechanism, radiation, head-tail and feedback. Perhaps it is essential to remove the photoelectrons around the positron beam explicitly. If we apply magnetic field fo about 20 G, the growth rate will be reduced. (S.Y.)


    Energy Technology Data Exchange (ETDEWEB)

    Shadmehri, Mohsen, E-mail: [Department of Physics, Faculty of Science, Golestan University, Gorgan 49138-15739 (Iran, Islamic Republic of)


    We study the stability of a dust layer in a gaseous disk subject to linear axisymmetric perturbations. Instead of considering single-size particles, however, the population of dust particles is assumed to consist of two grain species. Dust grains exchange momentum with the gas via the drag force and their self-gravity is also considered. We show that the presence of two grain sizes can increase the efficiency of the linear growth of drag-driven instability in the protoplanetary disks (PPDs). A second dust phase with a small mass, compared to the first dust phase, would reduce the growth timescale by a factor of two or more, especially when its coupling to the gas is weak. This means that once a certain amount of large dust particles form, even though it is much smaller than that of small dust particles, the dust layer becomes more unstable and dust clumping is accelerated. Thus, the presence of dust particles of various sizes must be considered in studies of dust clumping in PPDs where both large and small dust grains are present.

  3. Marangoni instabilities in two-layer systems due to concentration dependent transfer properties (United States)

    Trevelyan, P. M. J.; Pimienta, V.; Eckert, K.; de Wit, A.


    We consider a Hele-Shaw cell containing two immiscible liquids. A chemical species initially dissolved in an organic phase crosses the interface into the aqueous phase. In the aqueous phase this chemical reactant is involved in a reaction producing a surfactant which undergoes micellisation when the critical micelle concentration is reached. These micelles increase solubility which in turn increases the transfer rate and hence favours additional formation of micelles. To model such an autocatalytic increase of solubility, we consider here that the partition coefficient is a function of the surfactant concentration. Through the solutal Marangoni effect, this surfactant can induce tangential stresses leading to interfacial motion. The aim of our study is to theoretically examine the conditions for an instability in such a system. In particular, we seek to understand whether Marangoni effects can be observed because of a concentration dependent partition coefficient in a system that would be stable in the case of a constant partition coefficient according to the classical stability conditions of Sternling and Scriven (AIChE J., 5, p.514, 1959).

  4. Thin-disk laser scaling limit due to thermal-lens induced misalignment instability

    CERN Document Server

    Schuhmann, Karsten; Nez, Francois; Pohl, Randolf; Antognini, Aldo


    We present an obstacle in power scaling of thin-disk lasers related with self-driven growth of misalignment due to thermal lens effects. This self-driven growth arises from the changes of the optical phase difference at the disk caused by the excursion of the laser eigen-mode from the optical axis. We found a criterion based on a simplified model of this phenomenon which can be appied to design laser resonators insensitive to this effect.


    Energy Technology Data Exchange (ETDEWEB)

    Hirabayashi, Masatoshi [Research Associate, Colorado Center for Astrodynamics Research, Aerospace Engineering Sciences, University of Colorado Boulder (United States); Sánchez, Diego Paul [Senior Research Associate, Colorado Center for Astrodynamics Research, Aerospace Engineering Sciences, University of Colorado Boulder (United States); Scheeres, Daniel J., E-mail: [Richard Seebass Chair, Professor, Colorado Center for Astrodynamics Research, Aerospace Engineering Sciences, University of Colorado Boulder (United States)


    Surface shedding of an asteroid is a failure mode where surface materials fly off due to strong centrifugal forces beyond the critical spin period, while the internal structure does not deform significantly. This paper proposes a possible structure of an asteroid interior that leads to surface shedding due to rapid rotation rates. A rubble pile asteroid is modeled as a spheroid composed of a surface shell and a concentric internal core, the entire assembly called the test body. The test body is assumed to be uniformly rotating around a constant rotation axis. We also assume that while the bulk density and the friction angle are constant, the cohesion of the surface shell is different from that of the internal core. First, developing an analytical model based on limit analysis, we provide the upper and lower bounds for the actual surface shedding condition. Second, we use a Soft-sphere Discrete Element Method (SSDEM) to study dynamical deformation of the test body due to a quasi-static spin-up. In this paper we show the consistency of both approaches. Additionally, the SSDEM simulations show that the initial failure always occurs locally and not globally. In addition, as the core becomes larger, the size of lofted components becomes smaller. These results imply that if there is a strong core in a progenitor body, surface shedding is the most likely failure mode.

  6. Internal Structure of Asteroids Having Surface Shedding due to Rotational Instability

    CERN Document Server

    Hirabayashi, Masatoshi; Scheeres, Daniel J


    Surface shedding of an asteroid is a failure mode where surface materials fly off due to strong centrifugal forces beyond the critical spin period, while the internal structure does not deform significantly. This paper proposes a possible structure of an asteroid interior that leads to such surface shedding due to rapid rotation rates. A rubble pile asteroid is modeled as a spheroid composed of a surface shell and a concentric internal core, the entire assembly called the test body. The test body is assumed to be uniformly rotating around a constant rotation axis. We also assume that while the bulk density and the friction angle are constant, the cohesion of the surface shell is different from that of the internal core. First, developing an analytical model based on limit analysis, we provide the upper and lower bounds for the actual surface shedding condition. Second, we use a Soft-Sphere Discrete Element Method (SSDEM) to study dynamical deformation of the test body due to a quasi-static spin-up. In this pa...

  7. Efficient magnetic-field amplification due to the Kelvin-Helmholtz instability in binary neutron star mergers

    CERN Document Server

    Kiuchi, Kenta; Kyutoku, Koutarou; Sekiguchi, Yuichiro; Shibata, Masaru


    We explore magnetic-field amplification due to the Kelvin-Helmholtz instability during binary neutron star mergers. By performing high-resolution general relativistic magnetohydrodynamics simulations with a resolution of $17.5$ m for $4$--$5$ ms after the onset of the merger on the Japanese supercomputer "K", we find that an initial magnetic field of moderate maximum strength $10^{13}$ G is amplified at least by a factor of $\\approx 10^3$. We also explore the saturation of the magnetic-field energy and our result shows that it is likely to be $\\gtrsim 4 \\times 10^{50}$ erg, which is $\\gtrsim 0.1\\%$ of the bulk kinetic energy of the merging binary neutron stars.

  8. Lateral velocity estimation bias due to beamforming delay errors (Conference Presentation) (United States)

    Rodriguez-Molares, Alfonso; Fadnes, Solveig; Swillens, Abigail; Løvstakken, Lasse


    An artefact has recently been reported [1,2] in the estimation of the lateral blood velocity using speckle tracking. This artefact shows as a net velocity bias in presence of strong spatial velocity gradients such as those that occur at the edges of the filling jets in the heart. Even though this artifact has been found both in vitro and in simulated data, its causes are still undescribed. Here we demonstrate that a potential source of this artefact can be traced to smaller errors in the beamforming setup. By inserting a small offset in the beamforming delay, one can artificially create a net lateral movement in the speckle in areas of high velocity gradient. That offset does not have a strong impact in the image quality and can easily go undetected.

  9. Emergent Superstructural Dynamic Order due to Competing Antiferroelectric and Antiferrodistortive Instabilities in Bulk EuTiO3 (United States)

    Kim, Jong-Woo; Thompson, Paul; Brown, Simon; Normile, Peter S.; Schlueter, John A.; Shkabko, Andrey; Weidenkaff, Anke; Ryan, Philip J.


    Microscopic structural instabilities of EuTiO3 single crystals were investigated by synchrotron x-ray diffraction. Antiferrodistortive (AFD) oxygen octahedron rotational order was observed alongside Ti derived antiferroelectric distortions. The competition between the two instabilities is reconciled through a cooperatively modulated structure allowing both to coexist. The combination of electric and magnetic fields increases the population of the modulated AFD order, illustrating how the origin of the large magnetoelectric coupling derives from the dynamic equilibrium between AFD and polar instabilities.

  10. Hemi-Castaing ligamentoplasty for the treatment of chronic lateral ankle instability: a retrospective assessment of outcome

    NARCIS (Netherlands)

    T. Schepers (Tim); L.M.M. Vogels (Lucas); E.M.M. van Lieshout (Esther)


    textabstractPurpose: In the treatment of chronic ankle instability, most non-anatomical reconstructions use the peroneus brevis tendon. This, however, sacrifices the natural ankle stabilising properties of the peroneus brevis muscle. The aim of this study was to evaluate the functional outcome of pa

  11. Cortical T2 signal shortening in amyotrophic lateral sclerosis is not due to iron deposits

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, M.J.; Neundoerfer, B. [University of Erlangen-Nurenberg, Department of Neurology, Erlangen (Germany); Fellner, C.; Fellner, F.A. [University of Erlangen-Nurenberg, Institute of Diagnostic Radiology, Erlangen (Germany); Landes-Nervenklinik Wagner-Jauregg, Institute of Radiology, Linz (Austria); Schmid, A. [University of Erlangen-Nurenberg, Institute of Diagnostic Radiology, Erlangen (Germany)


    Signal shortening of the motor cortex in T2-weighted MR images is a frequent finding in patients with amyotrophic lateral sclerosis (ALS). The cause of signal shortening in ALS is unknown, although iron deposits have been suggested. To test this hypothesis, we acquired T2*-weighted gradient-echo (GRE) MR images in addition to T2-weighted turbo spin-echo in 69 patients with ALS. Signal shortening in T2-weighted images was found in 31 patients. In T2*-weighted GRE images, only three patients had signal shortening. One patient with additional bifrontal haemorrhage had frontal but no motor cortex signal shortening. Iron deposits do not cause cortical signal shortening in patients with ALS predominantly. Other factors are presumably more important in the generation of cortical T2 shortening in ALS. (orig.)

  12. Lateral OFC activity predicts decision bias due to first impressions during ultimatum games. (United States)

    Kim, Hackjin; Choi, Min-Jo; Jang, In-Ji


    Despite the prevalence and potentially harmful consequences of first impression bias during social decision-making, its precise neural underpinnings remain unclear. Here, on the basis of the fMRI study using ultimatum games, the authors show that the responders' decisions to accept or reject offers were significantly affected by facial trustworthiness of proposers. Analysis using a model-based fMRI method revealed that activity in the right lateral OFC (lOFC) of responders increased as a function of negative decision bias, indicating a greater likelihood of rejecting otherwise fair offers, possibly because of the facial trustworthiness of proposers. In addition, lOFC showed changes in functional connectivity strength with amygdala and insula as a function of decision bias, and individual differences in the strengths of connectivities between lOFC and bilateral insula were also found to predict the likelihood of responders to reject offers from untrustworthy-looking proposers. The present findings emphasize that the lOFC plays a pivotal role in integrating signals related to facial impression and creating signal biasing decisions during social interactions.


    Directory of Open Access Journals (Sweden)



    Full Text Available AIM: We present here the clinical results of 24 patients who were operated for cervical instability following trauma by lateral mass fixation at our institution between July 2010 and Dec 2013 and to assess the stability of the construct at 2yr follow - up study. MATERIALS AND METHODS: Between July 2010 and Dec 2013 a total of 24 pts. Were operated by lateral mass fixation for cervical spine instability following trauma to subaxial cervical spine between C3 - C6. Presenting with posterior element injury like facet locking and subluxation injuries were included in the study. Al l these patients were evaluated postoperatively for neurologic improvement , complications and Results were analyzed. RESULTS: A total of 104 screws were placed in to the lateral masses during the study. There were 8(33.3% deaths in this series not related to the surgical procedure. There were no immediate complications related to the procedure. There was no evidence of neurovascular injury either during the procedure or immediately following the surgery. There was CSF leak in one case of badly traumatized cord injury during the procedure. Neurological improvement was seen in 13(81.2% out of surviving 16 cases of trauma at the end of 3m to the extent of self - ambulation and the rest three did not show any improvement and remained quadriplegic. CONCLUSION: In this study we report good long term stability achieved by the lateral mass fixation with rods and screws with least morbidity and the safety of the procedure compared to other methods of posterier elements fixations. Both Roy Camille and Magerl technique can be followed for screw placement, where in Magerl technique has slight advantage of avoiding the nerve root injury and a longer screw can be placed to achieve a good bony purchase. Over all it is very safe and efficacious procedure in the hands of an ex perienced surgeon

  14. A semi-empirical model for the estimation of maximum horizontal displacement due to liquefaction-induced lateral spreading (United States)

    Faris, Allison T.; Seed, Raymond B.; Kayen, Robert E.; Wu, Jiaer


    During the 1906 San Francisco Earthquake, liquefaction-induced lateral spreading and resultant ground displacements damaged bridges, buried utilities, and lifelines, conventional structures, and other developed works. This paper presents an improved engineering tool for the prediction of maximum displacement due to liquefaction-induced lateral spreading. A semi-empirical approach is employed, combining mechanistic understanding and data from laboratory testing with data and lessons from full-scale earthquake field case histories. The principle of strain potential index, based primary on correlation of cyclic simple shear laboratory testing results with in-situ Standard Penetration Test (SPT) results, is used as an index to characterized the deformation potential of soils after they liquefy. A Bayesian probabilistic approach is adopted for development of the final predictive model, in order to take fullest advantage of the data available and to deal with the inherent uncertainties intrinstiic to the back-analyses of field case histories. A case history from the 1906 San Francisco Earthquake is utilized to demonstrate the ability of the resultant semi-empirical model to estimate maximum horizontal displacement due to liquefaction-induced lateral spreading.

  15. The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site

    Energy Technology Data Exchange (ETDEWEB)

    Zahn, Karl E.; Averill, April; Wallace, Susan S.; Doublié, Sylvie (Vermont)


    5-Hydroxycytosine (5-OHC) is a stable oxidation product of cytosine associated with an increased frequency of C {yields} T transition mutations. When this lesion escapes recognition by the base excision repair pathway and persists to serve as a templating base during DNA synthesis, replicative DNA polymerases often misincorporate dAMP at the primer terminus, which can lead to fixation of mutations and subsequent disease. To characterize the dynamics of DNA synthesis opposite 5-OHC, we initiated a comparison of unmodified dCMP to 5-OHC, 5-fluorocytosine (5-FC), and 5-methylcytosine (5-MEC) in which these bases act as templates in the active site of RB69 gp43, a high-fidelity DNA polymerase sharing homology with human replicative DNA polymerases. This study presents the first crystal structure of any DNA polymerase binding this physiologically important premutagenic DNA lesion, showing that while dGMP is stabilized by 5-OHC through normal Watson-Crick base pairing, incorporation of dAMP leads to unstacking and instability in the template. Furthermore, the electronegativity of the C5 substituent appears to be important in the miscoding potential of these cytosine-like templates. While dAMP is incorporated opposite 5-OHC {approx}5 times more efficiently than opposite unmodified dCMP, an elevated level of incorporation is also observed opposite 5-FC but not 5-MEC. Taken together, these data imply that the nonuniform templating by 5-OHC is due to weakened stacking capabilities, which allows dAMP incorporation to proceed in a manner similar to that observed opposite abasic sites.

  16. An analytical study on excitation of nuclear-coupled thermal-hydraulic instability due to seismically induced resonance in BWR

    Energy Technology Data Exchange (ETDEWEB)

    Hirano, Masashi [Japan Atomic Energy Research Institute, Ibaraki-ken (Japan)


    This paper describes the results of a scoping study on seismically induced resonance of nuclear-coupled thermal-hydraulic instability in BWRs, which was conducted by using TRAC-BF1 within a framework of a point kinetics model. As a result of the analysis, it is shown that a reactivity insertion could occur accompanied by in-surge of coolant into the core resulted from the excitation of the nuclear-coupled instability by the external acceleration. In order to analyze this phenomenon more in detail, it is necessary to couple a thermal-hydraulic code with a three-dimensional nuclear kinetics code.

  17. Scattering of electromagnetic waves from a plasma: Enhanced ion acoustic fluctuations due to ion-ion two-stream instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Wahlund, J.E.; Opgenoorth, H.J.; Persson, M.A.L. (Swedish Institute of Space Physics, Uppsala (Sweden)); Mishin, E.V.; Volokitin, A.S. (IZMIRAN, Troitsk, Moscow Region (Russian Federation)); Forme, F.R.E. (CNRS/CRPE (France))


    The authors propose an explanation for ion acoustic line spectra which have been observed by the EISCAT and Millstone Hill radars in the topside auroral ionosphere. They show that such lines can be generated in plasmas which are unstable to the ion-ion two-stream instability. This mechanism has the advantage of explaining the observed phenomena, and being consistent with typical conditions in the topside ionosphere.

  18. Standing striations due to ionization instability in atmospheric pressure He/H2O radio frequency capacitive discharges (United States)

    Kawamura, E.; Lieberman, M. A.; Lichtenberg, A. J.


    One-dimensional particle-in-cell (PIC) simulations of a narrow gap atmospheric pressure He/2%{{\\text{H}}2}\\text{O} radio frequency capacitive discharge showed standing striations in the bulk plasma region while previously conducted PIC simulations of a narrow gap atmospheric pressure He/0.1%{{\\text{N}}2} discharges [1] showed no such instabilities. We successively modified the base He/{{\\text{H}}2}\\text{O} chemistry to make it more similar to the He/{{\\text{N}}2} chemistry in order to determine the cause of the striations. Setting the e-{{\\text{H}}2}\\text{O} scattering, attachment, vibrational and rotational excitation rates to zero did not suppress the striations. However, a systematic reduction of the e-ion recombination cross section resulted in a transition to a stable state with no striations. The results are interpreted in terms of a model in which the balance between bulk direct ionization and bulk recombination loss determines the bulk plasma equilibrium. Perturbing the equilibrium, we find that the striations are consistent with an ionization instability induced by non-local electron kinetics that form a spatially-varying high energy tail of the electron energy distribution, causing the ionization rate coefficient to decrease with increasing electron temperature T e and root-mean-square electric field E in the instability regime.

  19. Determination of corrosion rate of reinforcement with a modulated guard ring electrode; analysis of errors due to lateral current distribution

    Energy Technology Data Exchange (ETDEWEB)

    Wojtas, H


    The main source of errors in measuring the corrosion rate of rebars on site is a non-uniform current distribution between the small counter electrode (CE) on the concrete surface and the large rebar network. Guard ring electrodes (GEs) are used in an attempt to confine the excitation current within a defined area. In order to better understand the functioning of modulated guard ring electrode and to assess its effectiveness in eliminating errors due to lateral spread of current signal from the small CE, measurements of the polarisation resistance performed on a concrete beam have been numerically simulated. Effect of parameters such as rebar corrosion activity, concrete resistivity, concrete cover depth and size of the corroding area on errors in the estimation of polarisation resistance of a single rebar has been examined. The results indicate that modulated GE arrangement fails to confine the lateral spread of the CE current within a constant area. Using the constant diameter of confinement for the calculation of corrosion rate may lead to serious errors when test conditions change. When high corrosion activity of rebar and/or local corrosion occur, the use of the modulated GE confinement may lead to significant underestimation of the corrosion rate.

  20. Time-dependent modeling of oscillatory instability of three-dimensional natural convection of air in a laterally heated cubic box (United States)

    Gelfgat, Alexander Yu.


    Transition from steady to oscillatory buoyancy convection of air in a laterally heated cubic box is studied numerically by straight-forward time integration of Boussinesq equations using a series of gradually refined finite volume grids. Horizontal and spanwise cube boundaries are assumed to be either perfectly thermally conducting or perfectly thermally insulated, which results in four different sets of thermal boundary conditions. Critical Grashof numbers are obtained by interpolation of numerically extracted growth/decay rates of oscillation amplitude to zero. Slightly supercritical flow regimes are described by time-averaged flows, snapshots, and spatial distribution of the oscillation amplitude. Possible similarities and dissimilarities with two-dimensional instabilities in laterally heated square cavities are discussed. Break of symmetries and sub- or supercritical character of bifurcations are examined. Three consequent transitions from steady to the oscillatory regime, from the oscillatory to the steady regime, and finally to the oscillatory flow, are found in the case of perfectly insulated horizontal and spanwise boundaries. Arguments for grid and time-step independence of the results are given.

  1. Two-stream cyclotron radiative instabilities due to the marginally mirror-trapped fraction for fustion alphas in tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    Arunasalam, V.


    It is shown here that the marginally mirror-trapped fraction of the newly-born fusion alpha particles in the deuterium-tritium (DT) reaction dominated tokamak plasmas can induce a two-stream cyclotron radiative instability for the fast Alfven waves propagating near the harmonics of the alpha particle cyclotron frequency {omega}{sub c{alpha}}. This can explain both the experimentally observed time behavior and the spatially localized origin of the fusion product ion cyclotron emission (ICE) in TFTR at frequencies {omega} {approx} m{omega}{sub c{alpha}}.

  2. Plasma-Sheath Instability in Hall Thrusters Due to Periodic Modulation of the Energy of Secondary Electrons in Cyclotron Motion

    Energy Technology Data Exchange (ETDEWEB)

    Sydorenko, D.; Smolyakov, A.; Kaganovich, I.; Raitses, Y.


    Particle-in-cell simulation of Hall thruster plasmas reveals a plasma-sheath instability manifesting itself as a rearrangement of the plasma sheath near the thruster channel walls accompanied by a sudden change of many discharge parameters. The instability develops when the sheath current as a function of the sheath voltage is in the negative conductivity regime. The major part of the sheath current is produced by beams of secondary electrons counter-streaming between the walls. The negative conductivity is the result of nonlinear dependence of beam-induced secondary electron emission on the plasma potential. The intensity of such emission is defined by the beam energy. The energy of the beam in crossed axial electric and radial magnetic fields is a quasi-periodical function of the phase of cyclotron rotation, which depends on the radial profile of the potential and the thruster channel width. There is a discrete set of stability intervals determined by the final phase of the cyclotron rotation of secondary electrons. As a result, a small variation of the thruster channel width may result in abrupt changes of plasma parameters if the plasma state jumps from one stability interval to another.

  3. Roles of bulk viscosity on Rayleigh-Taylor instability: Non-equilibrium thermodynamics due to spatio-temporal pressure fronts (United States)

    Sengupta, Tapan K.; Sengupta, Aditi; Sharma, Nidhi; Sengupta, Soumyo; Bhole, Ashish; Shruti, K. S.


    Direct numerical simulations of Rayleigh-Taylor instability (RTI) between two air masses with a temperature difference of 70 K is presented using compressible Navier-Stokes formulation in a non-equilibrium thermodynamic framework. The two-dimensional flow is studied in an isolated box with non-periodic walls in both vertical and horizontal directions. The non-conducting interface separating the two air masses is impulsively removed at t = 0 (depicting a heaviside function). No external perturbation has been used at the interface to instigate the instability at the onset. Computations have been carried out for rectangular and square cross sections. The formulation is free of Boussinesq approximation commonly used in many Navier-Stokes formulations for RTI. Effect of Stokes' hypothesis is quantified, by using models from acoustic attenuation measurement for the second coefficient of viscosity from two experiments. Effects of Stokes' hypothesis on growth of mixing layer and evolution of total entropy for the Rayleigh-Taylor system are reported. The initial rate of growth is observed to be independent of Stokes' hypothesis and the geometry of the box. Following this stage, growth rate is dependent on the geometry of the box and is sensitive to the model used. As a consequence of compressible formulation, we capture pressure wave-packets with associated reflection and rarefaction from the non-periodic walls. The pattern and frequency of reflections of pressure waves noted specifically at the initial stages are reflected in entropy variation of the system.

  4. Roles of bulk viscosity on Rayleigh-Taylor instability: Non-equilibrium thermodynamics due to spatio-temporal pressure fronts

    Energy Technology Data Exchange (ETDEWEB)

    Sengupta, Tapan K., E-mail:; Bhole, Ashish; Shruti, K. S. [HPCL, Department of Aerospace Engineering, IIT Kanpur, Kanpur, UP (India); Sengupta, Aditi [Department of Engineering, University of Cambridge, Cambridge (United Kingdom); Sharma, Nidhi [Graduate Student, HPCL, Department of Aerospace Engineering, IIT Kanpur, Kanpur, UP (India); Sengupta, Soumyo [Department of Mechanical and Aerospace Engineering, Ohio State University, Columbus, Ohio 43210 (United States)


    Direct numerical simulations of Rayleigh-Taylor instability (RTI) between two air masses with a temperature difference of 70 K is presented using compressible Navier-Stokes formulation in a non-equilibrium thermodynamic framework. The two-dimensional flow is studied in an isolated box with non-periodic walls in both vertical and horizontal directions. The non-conducting interface separating the two air masses is impulsively removed at t = 0 (depicting a heaviside function). No external perturbation has been used at the interface to instigate the instability at the onset. Computations have been carried out for rectangular and square cross sections. The formulation is free of Boussinesq approximation commonly used in many Navier-Stokes formulations for RTI. Effect of Stokes’ hypothesis is quantified, by using models from acoustic attenuation measurement for the second coefficient of viscosity from two experiments. Effects of Stokes’ hypothesis on growth of mixing layer and evolution of total entropy for the Rayleigh-Taylor system are reported. The initial rate of growth is observed to be independent of Stokes’ hypothesis and the geometry of the box. Following this stage, growth rate is dependent on the geometry of the box and is sensitive to the model used. As a consequence of compressible formulation, we capture pressure wave-packets with associated reflection and rarefaction from the non-periodic walls. The pattern and frequency of reflections of pressure waves noted specifically at the initial stages are reflected in entropy variation of the system.

  5. Toroidal momentum pinch velocity due to the coriolis drift effect on small scale instabilities in a toroidal plasma. (United States)

    Peeters, A G; Angioni, C; Strintzi, D


    In this Letter, the influence of the "Coriolis drift" on small scale instabilities in toroidal plasmas is shown to generate a toroidal momentum pinch velocity. Such a pinch results because the Coriolis drift generates a coupling between the density and temperature perturbations on the one hand and the perturbed parallel flow velocity on the other. A simple fluid model is used to highlight the physics mechanism and gyro-kinetic calculations are performed to accurately assess the magnitude of the pinch. The derived pinch velocity leads to a radial gradient of the toroidal velocity profile even in the absence of a torque on the plasma and is predicted to generate a peaking of the toroidal velocity profile similar to the peaking of the density profile. Finally, the pinch also affects the interpretation of current experiments.

  6. Extra dissipation and flow uniformization due to elastic instabilities of shear-thinning polymer solutions in model porous media (United States)

    Machado, Anaïs; Bodiguel, Hugues; Beaumont, Julien; Clisson, Gérald; Colin, Annie


    We study flows of hydrolized polyacrylamide solutions in two dimensional porous media made using microfluidics, for which elastic effects are dominant. We focus on semi-dilute solutions (0.1%–0.4%) which exhibit a strong shear thinning behavior. We systematically measure the pressure drop and find that the effective permeability is dramatically higher than predicted when the Weissenberg number is greater than about 10. Observations of the streamlines of the flow reveal that this effect coincides with the onset of elastic instabilities. Moreover, and importantly for applications, we show using local measurements that the mean flow is modified: it appears to be more uniform at high Weissenberg number than for Newtonian fluids. These observations are compared and discussed using pore network simulations, which account for the effect of disorder and shear thinning on the flow properties. PMID:27478522

  7. Analysis and determination of susceptibility Risk from slope instability at Colima State Mexico due to the accelerators factors of rain and seismicity (United States)

    Ramirez-Ruiz, J. J.


    Slope instability is presented each year in the mountain region of the Colima State, Mexico. It occurs due to the combination of different factors existing in this area as: Precipitation, topography contrast, type and mechanical properties of deposits that constitute the rocks and soils of the region and the erosion due to the elimination of vegetation deck to develop and grow urban areas. To these geological factors we can extend the tectonic activity of the Western part of Mexico that originate high seismicity by the interaction of Cocos plate and North America plate forming the region of Graben de Colima, were is located our study area. Here we will present a Zonification and determination of the Susceptibility maps of slope instability due to the rain and seismicity accelerators factors. The North part of the State Colima is covered by deposits of the Volcan de Colima with an elevation of 3860 masl. It is the area of major precipitation yearly with more than 1200 mm in comparison to the average precipitation of about 900 mm of the State of Colima. Using a SIG system and the mapping of more than 30 sites we realize a zonification and analysis of the Risk using a methodology developed by CENAPRED. The susceptibility map developed in this area in combination with erosion factors permit us to determine an approximation of the Risk considering some limitations that will be present in this study.

  8. Quad-Bike Operational Instability

    Directory of Open Access Journals (Sweden)

    Ross H. Macmillan


    Full Text Available The stake-holders in the quad-bike (QB industry in Australia have failed to reach a satisfactory resolution of the present impasse that exists with respect to the causes and mitigation of the trauma suffered by riders due to QB instability. In an effort to provide purchasers with data enabling them to discriminate between safer and less safe machines, static longitudinal and lateral tests have been conducted by various interested parties; quasi-static lateral tests have also been conducted under some operational conditions. It is argued that while these static tests are valid, under many operating conditions QBs will not reach such unstable slopes due to poor traction. Further, these tests do not include the quasi-static and dynamic factors which also influence the processes associated with operational instability. For these reasons, the static tests do not provide an adequate basis for discrimination between safer and less safe machines.

  9. Atlanto-axial malformation and instability in dogs with pituitary dwarfism due to an LHX3 mutation. (United States)

    Voorbij, A M W Y; Meij, B P; van Bruggen, L W L; Grinwis, G C M; Stassen, Q E M; Kooistra, H S


    Canine pituitary dwarfism or combined pituitary hormone deficiency (CPHD) in shepherd dogs is associated with an LHX3 mutation and can lead to a wide range of clinical manifestations. Some dogs with CPHD have neurological signs that are localized to the cervical spine. In human CPHD, caused by an LHX3 mutation, anatomical abnormalities in the atlanto-axial (C1-C2) joint have been described. To evaluate the presence of atlanto-axial malformations in dogs with pituitary dwarfism associated with an LHX3 mutation and to investigate the degree of similarity between the atlanto-axial anomalies found in canine and human CPHD patients with an LHX3 mutation. Three client-owned Czechoslovakian wolfdogs and 1 client-owned German shepherd dog, previously diagnosed with pituitary dwarfism caused by an LHX3 mutation, with neurological signs indicating a cervical spinal disorder. Radiography, computed tomography, and magnetic resonance imaging of the cranial neck and skull, necropsy, and histology. Diagnostic imaging identified abnormal positioning of the dens axis and incomplete ossification of the suture lines between the ossification centers of the atlas with concurrent atlanto-axial instability and dynamic compression of the spinal cord by the dens axis. The malformations and aberrant motion at C1-C2 were confirmed at necropsy and histology. The atlanto-axial abnormalities of the dwarf dogs resemble those encountered in human CPHD patients with an LHX3 mutation. These findings suggest an association between the LHX3 mutation in dogs with CPHD and atlanto-axial malformations. Consequently, pituitary dwarfs should be monitored closely for neurological signs. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of American College of Veterinary Internal Medicine.

  10. Interferometric radar observations of filamented structures due to plasma instabilities and their relation to dynamic auroral rays

    Directory of Open Access Journals (Sweden)

    T. Grydeland


    -electron two-stream mechanism favoured by many authors is an unlikely candidate to explain the observations. The video data has helped establish a clear correlation between the enhanced echoes and auroral activity, on sub-second time scales, showing a threshold connection between the auroral intensity and the triggering of the radar enhancements. It appears that the up- and down-shifted enhanced echoes correlate with fine auroral structures in different ways.

    Key words. Ionosphere (auroral ionosphere; plasma waves and instabilities – Radio science (interferometry

  11. Early social instability affects plasma testosterone during adolescence but does not alter reproductive capacity or measures of stress later in life. (United States)

    Siegeler, Katja; Wistuba, Joachim; Damm, Oliver S; von Engelhardt, Nikolaus; Sachser, Norbert; Kaiser, Sylvia


    The social environment plays an important role in modulating processes of the hormonal and behavioural profile of an animal in a variety of group-living species. In wild cavies for instance, unstable social environmental conditions during pregnancy and lactation lead to an infantilised biobehavioural profile of the male offspring. In the present study, the influence of the social environment during pregnancy and lactation on the male wild cavy offsprings' plasma testosterone development, reproductive capacity and stress system activity was investigated. To this purpose, 12 sons whose mothers had lived in an unstable social environment during pregnancy and lactation were compared with 12 sons whose mothers had lived in a stable social environment during the same time. Plasma testosterone (T) and plasma cortisol (C) concentrations were determined from days 20 to 107 of age. Adrenal tyrosine hydroxylase (TH) activity and different parameters of reproductive capacity (weights of testes, epididymides and accessory sex glands, cellular composition of the testes, DNA fragmentation indices and sperm motility parameters) were analysed at day 107 of age. TH activity and plasma C were unaffected by different social environmental conditions early in life. The developmental time course of T concentrations, however, was significantly different: Sons whose mothers had lived in an unstable social environment during pregnancy and lactation showed a delayed increase in T concentrations around adolescence compared to controls. In contrast, no reproduction-related parameters measured within this study differed significantly between the two groups. Thus, early social instability affects plasma testosterone development during adolescence in a significant way but does not alter reproductive capacity or measures of stress later in life.

  12. Catastrophic failure of hip arthroscopy due to iatrogenic instability: can partial division of the ligamentum teres and iliofemoral ligament cause subluxation? (United States)

    Mei-Dan, Omer; McConkey, Mark O; Brick, Matthew


    Hip arthroscopy is an evolving surgical tool, and with any new procedure, it is important to learn from the complications encountered. A patient with mild hip dysplasia and a symptomatic labral tear underwent uneventful hip arthroscopy and labral repair including partial debridement of a hypertrophied ligamentum teres. Despite preservation of the labrum, no pincer resection, and a modest capsulotomy, 3 months, subluxation and joint space narrowing were noted. One year, end-stage arthritis was present, requiring total hip replacement. Instability after hip arthroscopy is due to a number of factors, including excessive rim trimming, capsulotomy, overzealous labral resection, or inadequate labral repair. This report emphasizes the importance of the ligamentum teres and small disruptions of the capsule in patients with mild dysplasia.

  13. Instability of the hindfoot after lesion of the lateral ankle ligaments: investigations of the anterior drawer and adduction maneuvers in autopsy specimens

    DEFF Research Database (Denmark)

    Kjaersgaard-Andersen, P.; Frich, Lars Henrik; Madsen, F.;


    instability in adduction, whereas further lesion to the CFL increased adduction in the entire range of flexion, with a maximum median of 14.2 degrees in dorsiflexion. The anterior drawer maneuver can reveal a combined lesion of the ATL and CFL if performed with the tibiotalocalcaneal joint complex...... in dorsiflexion. Significant clinical instability in adduction will only take place when a combined lesion of the ATL and CFL is present....

  14. Expression of S100A6 in Rat Hippocampus after Traumatic Brain Injury Due to Lateral Head Acceleration

    Directory of Open Access Journals (Sweden)

    Bo Fang


    Full Text Available In a rat model of traumatic brain injury (TBI, we investigated changes in cognitive function and S100A6 expression in the hippocampus. TBI-associated changes in this protein have not previously been reported. Rat S100A6 was studied via immunohistochemical staining, Western blot, and reverse transcription-polymerase chain reaction (RT-PCR after either lateral head acceleration or sham. Reduced levels of S100A6 protein and mRNA were observed 1 h after TBI, followed by gradual increases over 6, 12, 24, and 72 h, and then a return to sham level at 14 day. Morris water maze (MWM test was used to evaluate animal spatial cognition. TBI- and sham-rats showed an apparent learning curve, expressed as escape latency. Although TBI-rats displayed a relatively poorer cognitive ability than sham-rats, the disparity was not significant early post-injury. Marked cognitive deficits in TBI-rats were observed at 72 h post-injury compared with sham animals. TBI-rats showed decreased times in platform crossing in the daily MWM test; the performance at 72 h post-injury was the worst. In conclusion, a reduction in S100A6 may be one of the early events that lead to secondary cognitive decline after TBI, and its subsequent elevation is tightly linked with cognitive improvement. S100A6 may play important roles in neuronal degeneration and regeneration in TBI.

  15. Reduced phototropism in pks mutants may be due to altered auxin-regulated gene expression or reduced lateral auxin transport. (United States)

    Kami, Chitose; Allenbach, Laure; Zourelidou, Melina; Ljung, Karin; Schütz, Frédéric; Isono, Erika; Watahiki, Masaaki K; Yamamoto, Kotaro T; Schwechheimer, Claus; Fankhauser, Christian


    Phototropism allows plants to orient their photosynthetic organs towards the light. In Arabidopsis, phototropins 1 and 2 sense directional blue light such that phot1 triggers phototropism in response to low fluence rates, while both phot1 and phot2 mediate this response under higher light conditions. Phototropism results from asymmetric growth in the hypocotyl elongation zone that depends on an auxin gradient across the embryonic stem. How phototropin activation leads to this growth response is still poorly understood. Members of the phytochrome kinase substrate (PKS) family may act early in this pathway, because PKS1, PKS2 and PKS4 are needed for a normal phototropic response and they associate with phot1 in vivo. Here we show that PKS proteins are needed both for phot1- and phot2-mediated phototropism. The phototropic response is conditioned by the developmental asymmetry of dicotyledonous seedlings, such that there is a faster growth reorientation when cotyledons face away from the light compared with seedlings whose cotyledons face the light. The molecular basis for this developmental effect on phototropism is unknown; here we show that PKS proteins play a role at the interface between development and phototropism. Moreover, we present evidence for a role of PKS genes in hypocotyl gravi-reorientation that is independent of photoreceptors. pks mutants have normal levels of auxin and normal polar auxin transport, however they show altered expression patterns of auxin marker genes. This situation suggests that PKS proteins are involved in auxin signaling and/or lateral auxin redistribution.

  16. [Carpal instability]. (United States)

    Redeker, J; Vogt, P M


    Carpal instability can be understood as a disturbed anatomical alignment between bones articulating in the carpus. This disturbed balance occurs either only dynamically (with movement) under the effect of physiological force or even statically at rest. The most common cause of carpal instability is wrist trauma with rupture of the stabilizing ligaments and adaptive misalignment following fractures of the radius or carpus. Carpal collapse plays a special role in this mechanism due to non-healed fracture of the scaphoid bone. In addition degenerative inflammatory alterations, such as chondrocalcinosis or gout, more rarely aseptic bone necrosis of the lunate or scaphoid bones or misalignment due to deposition (Madelung deformity) can lead to wrist instability. Under increased pressure the misaligned joint surfaces lead to bone arrosion with secondary arthritis of the wrist. In order to arrest or slow down this irreversible process, diagnosis must occur as early as possible. Many surgical methods have been thought out to regain stability ranging from direct reconstruction of the damaged ligaments, through ligament replacement to partial stiffening of the wrist joint.

  17. Summary of information on low-speed lateral-directional derivatives due to rate of change of sideslip beta prime (United States)

    Coe, P. L., Jr.; Graham, A. B.; Chambers, J. R.


    The results presented show that the magnitudes of the aerodynamic stability derivatives due to rate of change of sideslip become quite large at high angles of attack for swept- and delta-wing configurations, and that such derivatives have large effects on the calculated dynamic stability of these configurations at high angles of attack. The wind-tunnel test techniques used to measure the beta prime derivatives and various approaches used to predict them are discussed. Both the conventional oscillating-airfoil theory and the lag-of-the-sidewash theory are shown to be inadequate for predicting the vertical-tail contribution to the acceleration-in-sideslip derivative; a flow-field-lag theory, which is discussed, appears to give qualitative agreement with experimental data for a current twin-jet fighter configuration.

  18. Benzene on Cu(111): II. Molecular assembly due to Lateral van der Waals and Surface-State-Mediated Indirect Interactions (United States)

    Hyldgaard, Per; Berland, Kristian; Einstein, T. L.


    Experiments show that benzene condenses into two different structural phases: a compact and a sparse phase, both of approximately hexagonal symmetry. The vdW-DF calculations demonstrate that the denser benzene-overlayer phase, with lattice constant 6.74 ,s due to direct benzene-benzene vdW attraction. The structure of the second, sparser phase, with lattice spacing 10.24 ,s attributed to the indirect electronic interactions mediated by the well-known metallic surface state on Cu(111). To support this claim, we use a formal Harris-functional approach to evaluate nonperturbatively the asymptotic form of this indirect interaction. Our extended vdW-DF scheme---which combines calculations of molecular physisorption, of direct intermolecular vdW coupling, and of indirect electronic interactions between the molecular adsorbates---accounts well for the structural phases of benzene on Cu(111). Our preliminary vdW-DF study of acene and quinone interactions provides building blocks for modeling of anthraquinone assembly on Cu(111).footnotetextG. Pawin, , L. Bartels, Science 313 (2006) 961

  19. Acceleration of plasma electrons by intense nonrelativistic ion and electron beams propagating in background plasma due to two-stream instability (United States)

    Kaganovich, Igor D.


    In this paper we study the effects of the two-stream instability on the propagation of intense nonrelativistic ion and electron beams in background plasma. Development of the two-stream instability between the beam ions and plasma electrons leads to beam breakup, a slowing down of the beam particles, acceleration of the plasma particles, and transfer of the beam energy to the plasma particles and wave excitations. Making use of the particle-in-cell codes EDIPIC and LSP, and analytic theory we have simulated the effects of the two-stream instability on beam propagation over a wide range of beam and plasma parameters. Because of the two-stream instability the plasma electrons can be accelerated to velocities as high as twice the beam velocity. The resulting return current of the accelerated electrons may completely change the structure of the beam self - magnetic field, thereby changing its effect on the beam from focusing to defocusing. Therefore, previous theories of beam self-electromagnetic fields that did not take into account the effects of the two-stream instability must be significantly modified. This effect can be observed on the National Drift Compression Experiment-II (NDCX-II) facility by measuring the spot size of the extracted beamlet propagating through several meters of plasma. Particle-in-cell, fluid simulations, and analytical theory also reveal the rich complexity of beam- plasma interaction phenomena: intermittency and multiple regimes of the two-stream instability in dc discharges; band structure of the growth rate of the two-stream instability of an electron beam propagating in a bounded plasma and repeated acceleration of electrons in a finite system. In collaboration with E. Tokluoglu, D. Sydorenko, E. A. Startsev, J. Carlsson, and R. C. Davidson. Research supported by the U.S. Department of Energy.

  20. Minimally invasive presacral approach for revision of an Axial Lumbar Interbody Fusion rod due to fall-related lumbosacral instability: a case report

    Directory of Open Access Journals (Sweden)

    Cohen Anders


    Full Text Available Abstract Introduction The purpose of this study was to describe procedural details of a minimally invasive presacral approach for revision of an L5-S1 Axial Lumbar Interbody Fusion rod. Case presentation A 70-year-old Caucasian man presented to our facility with marked thoracolumbar scoliosis, osteoarthritic changes characterized by high-grade osteophytes, and significant intervertebral disc collapse and calcification. Our patient required crutches during ambulation and reported intractable axial and radicular pain. Multi-level reconstruction of L1-4 was accomplished with extreme lateral interbody fusion, although focal lumbosacral symptoms persisted due to disc space collapse at L5-S1. Lumbosacral interbody distraction and stabilization was achieved four weeks later with the Axial Lumbar Interbody Fusion System (TranS1 Inc., Wilmington, NC, USA and rod implantation via an axial presacral approach. Despite symptom resolution following this procedure, our patient suffered a fall six weeks postoperatively with direct sacral impaction resulting in symptom recurrence and loss of L5-S1 distraction. Following seven months of unsuccessful conservative care, a revision of the Axial Lumbar Interbody Fusion rod was performed that utilized the same presacral approach and used a larger diameter implant. Minimal adhesions were encountered upon presacral re-entry. A precise operative trajectory to the base of the previously implanted rod was achieved using fluoroscopic guidance. Surgical removal of the implant was successful with minimal bone resection required. A larger diameter Axial Lumbar Interbody Fusion rod was then implanted and joint distraction was re-established. The radicular symptoms resolved following revision surgery and our patient was ambulating without assistance on post-operative day one. No adverse events were reported. Conclusions The Axial Lumbar Interbody Fusion distraction rod may be revised and replaced with a larger diameter rod using


    Directory of Open Access Journals (Sweden)

    V. Ovsianko


    Full Text Available The paper reveals a brand-new direction in simulation of frame and continual structures while calculating static and dynamic loads and stability.  An electronic model has been synthesized  for an investigated object and then it has been analyzed not with the help of  specialized analog computing techniques but by means of high-performance software package for electronic circuit calculation using a personal computer.The given paper contains exact algebraic equations corresponding to differential equations for lateral bending calculation of frame structures without and with due account of viscoelastic material properties in compliance with the Kelvin model.The exact algebraic equation for a beam on elastic supports (or elastic Winkler foundation has been derived for quartic differential equation.The paper presents a number of exact algebraic equations which are equivalent to differential equations for transverse-longitudinal bending calculation of frame structures without and with due account of viscoelastic material properties when lateral and longitudinal loads are applied in the form of  impulses with any periods of their duration and any interchangeability. 

  2. Integrating a MRI scanner with a 6 MV radiotherapy accelerator: dose increase at tissue-air interfaces in a lateral magnetic field due to returning electrons

    Energy Technology Data Exchange (ETDEWEB)

    Raaijmakers, A J E; Raaymakers, B W; Lagendijk, J J W [Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht (Netherlands)


    In the framework of the development of the integration of a MRI-scanner with a linear accelerator, the influence of a lateral, magnetic field on the dose distribution has to be determined. Dose increase is expected at tissue-air boundaries, due to the electron return effect (ERE): electrons entering air will describe a circular path and return into the phantom causing extra dose deposition. Using IMRT with many beam directions, this exit dose will not constitute a problem. Dose levels behind air cavities will decrease because of the absence of electrons crossing the cavity. The ERE has been demonstrated both by simulation and experiment. Monte Carlo simulations are performed with GEANT4, irradiating a water-air-water phantom in a lateral magnetic field. Also an air tube in water has been simulated, resulting in slightly twisted regions of dose increase and decrease. Experimental demonstration is achieved by film measurement in a perspex-air-perspex phantom in an electromagnet. Although the ERE causes dose increase before air cavities, relatively flat dose profiles can be obtained for the investigated cases using opposite beam configurations. More research will be necessary whether this holds for more realistic geometries with the use of IMRT and whether the ERE can be turned to our advantage when treating small tumour sites at air cavities.

  3. Guyon's canal syndrome due to tortuous ulnar artery with DeQuervain stenosing tenosynovitis, ligamentous injuries and dorsal intercalated segmental instability syndrome, a rare presentation: a case report


    Zeeshan, Muhammad; Ahmed, Farhan; Kanwal, Darakhshan; Khalid, Qazi Saad Bin; Ahmed, Muhammad Nadeem


    The Guyon's canal syndrome is a well known clinical entity and may have significant impact on patient's quality of life. We report a case of 43-year-old male who presented with complaints of pain and numbness in right hand and difficulty in writing for past one month. On imaging diagnosis of Guyon's canal syndrome because of tortuous ulnar artery was made with additional findings of DeQuervain's stenosing tenosynovitis and dorsal intercalated segmental instability syndrome with ligamentous in...

  4. Meniscectomy of horizontal tears of the lateral meniscus anterior horn using the joystick technique. (United States)

    Park, Ill Ho; Kim, Sung Jae; Choi, Duck Hyun; Lee, Su Chan; Park, Ha Young; Jung, Kwang Am


    Unstable inferior leaves of the anterior horn in horizontal tears of the lateral meniscus are challenging lesions for most orthopedic surgeons due to the poor viewing angle and the instability of these lesions. Resection of an exact volume is required for the successful treatment of horizontal tears in the lateral meniscus anterior horn. We report a method based on the joystick technique.

  5. Genetic instability in Gynecological Cancer

    Institute of Scientific and Technical Information of China (English)

    ZHAO Qing-hua; ZHOU Hong-lin


    Defects of mismatch repair (MMR) genes also have beenidentified in many kinds of tumors. Loss of MMR functionhas been linked to genetic instability especially microsatelliteinstability that results in high mutation rate. In this review, wediscussed the microsatellite instability observed in thegynecological tumors. We also discussed defects in the DNAmismatch repair in these tumors and their correlation to themicrosatellite instability, as well as the gene mutations due tothe microsatellite instability in these tumors. From thesediscussion, we tried to understand the mechanism ofcarcinogenesis in gynecological tumors from the aspect ofgenetic instability due to mismatch repair defects.

  6. Guyon's canal syndrome due to tortuous ulnar artery with DeQuervain stenosing tenosynovitis, ligamentous injuries and dorsal intercalated segmental instability syndrome, a rare presentation: a case report. (United States)

    Zeeshan, Muhammad; Ahmed, Farhan; Kanwal, Darakhshan; Khalid, Qazi Saad Bin; Ahmed, Muhammad Nadeem


    The Guyon's canal syndrome is a well known clinical entity and may have significant impact on patient's quality of life. We report a case of 43-year-old male who presented with complaints of pain and numbness in right hand and difficulty in writing for past one month. On imaging diagnosis of Guyon's canal syndrome because of tortuous ulnar artery was made with additional findings of DeQuervain's stenosing tenosynovitis and dorsal intercalated segmental instability syndrome with ligamentous injury and subsequently these were confirmed on surgery.Although it is a rare syndrome, early diagnosis and treatment prevents permanent neurological deficits and improve patient's quality of life.

  7. Spatio-temporal development of the filaments due to the thermal self-focusing instability near the critical surface in ionospheric plasmas (United States)

    Gondarenko, N. A.; Guzdar, P. N.; Milikh, G. M.; Sharma, A. S.; Papadopoulos, K.; Ossakow, S. L.


    We study fully nonlinear spatio-temporal development of the thermal self-focusing instability of high-power radio waves near the critical surface of the ionosphere. These simulations improve on our earlier work by including an evolution equation for the density instead of using the assumption of constant pressure to determine the perturbed density connected with the known temperature perturbation. Using our two-dimensional nonlinear code we analyze the time scale and associated velocity for the development of the field-aligned irregularities as they spread from the critical surface both in the underdense as well as the overdense regions. The scaling of this velocity as a function of the radiated power of the heater electromagnetic wave (ERP) is determined. We also study the characteristic size of the self-focused filament as a function of ERP. Finally, the spectrum of the density and temperature fluctuations as well as modifications in the equilibrium values of these parameters for different values of ERP are presented.

  8. 带线锚钉结合改良Brostr(o)m法修复慢性踝关节外侧不稳%Suture anchors in treatment of chronic lateral ankle instability using modified Brostr(o)m technique

    Institute of Scientific and Technical Information of China (English)

    陈刚; 陈封明; 任鹏; 李兵兵; 陈立; 周阳


    Objective To discuss the application of suture anchors in the treatment of chronic lateral ankle instability using the modified Brostr(o)m technique.Methods From May 2009 to May 2011,we admitted 16 patients with ankle sprain of degree Ⅲ who had had little improvement after conservative treatment for more than 6 months and deteriorated into chronic lateral ankle instability.They were 7 men and 9 women,aged from 19 to 31 years (average,23.6 years).They all had mild swelling,pain and instability at the lateral ankle.We treated them with suture anchors using the modified Brostr(o)m technique.The pre-and post-operative ankle functions were evaluated by American Orthopaedic Foot and Ankle Society(AOFAS) scores.The patients' subjective feeling after operation was evaluated by the Good grading system.Results The patients were followed up for 6 to 24 months (average,16 months).The AOFAS ankle and hindfoot score improved significantly from preoperative 65.00 ± 6.65 points to postoperative 92.06 ± 3.13 points,the talar antedisplacement from preoperative 11.38 ±2.23 mm to postoperative 3.19 ± 1.1 mm,and the talar tilt angle from preoperative 13.44° ± 2.25° to postoperative 4.69° ± 1.35° (P < 0.05).By the Good grading system for postoperative symptoms,there were 8 cases of grade Ⅰ,6 cases of grade Ⅱ,2 cases of grade Ⅲ and no case of grade Ⅳ,giving a good to excellent rate of 87.5%.Conclusion Suture anchors and modified Brostr(o)m technique is a reasonable and effective surgical method for the treatment of chronic lateral ankle instability.%目的 探讨带线锚钉结合改良Brostr(o)m法修复慢性踝关节外侧不稳的方法和疗效.方法 对2009年5月至2011年5月间收治16例慢性踝关节不稳患者进行回顾性分析,其中男7例,女9例;年龄19 ~31岁,平均23.6岁;均有踝关节外侧轻度肿胀、疼痛、不稳感,均为6个月以上的陈旧性损伤,而且经过3~6个月康复训练无改善,反复扭伤.均采用

  9. El malestar por inestabilidad laboral y su relación con tensión y recursos personales Uneasiness due to Job instability and its relationship With psychological strain and personnal resources

    Directory of Open Access Journals (Sweden)

    N. Leibovich de Figueroa


    Full Text Available La inestabilidad laboral se ha tornado uno de los estresores psicosociales más relevantes en las últimas décadas y su percepción podría generar malestar y sufrimiento, desembocando en un estado de estrés con la consecuente elevación de tensión en uno o varios de sus canales de expresión, provocando así efectos deletéreos en la salud psico-física de los trabajadores. Nos preguntamos qué aspectos personales y laborales de los trabajadores estarían vinculados a un mayor malestar debido a la inestabilidad laboral y si éste es predictor de la tensión psicológica que manifiesta el trabajador. El IMPIL, en su versión reducida, junto con otras técnicas, fue administrado a una muestra de 90 empleados en relación de dependencia. Concluimos que la inestabilidad laboral impacta negativamente en el trabajador a través de uno de los canales de expresión: el malestar, sobre todo si existe un desajuste entre el nivel de instrucción y la tarea que realiza. A su vez, corroboramos que la inestabilidad laboral y el malestar que la misma genera producen altos niveles de tensión psicológica en el trabajador.In the last decades job instability has become one of the most important psychosocial stressors and its perception could generate uneasiness and suffering, leading to a stressful state with a consequent increase of strain through one or several of its channels of expression, producing deleterious effects in the psychophysical health of workers. We wonder which workers' personal and job features could be related to a greater uneasiness due to job instability and if this job instability is a predictor of the psychological strain expressed by them. The IMPIL, in its reduced version, and other techniques were administered to a sample of 90 salaried employees. We conclude that job instability has a negative impact on the worker through one of the channels of expression: uneasiness, most of all if there exists a maladjustement between the

  10. Spondylolisthesis and Posterior Instability

    Energy Technology Data Exchange (ETDEWEB)

    Niggemann, P.; Beyer, H.K.; Frey, H.; Grosskurth, D. (Privatpraxis fuer Upright MRT, Koeln (Germany)); Simons, P.; Kuchta, J. (Media Park Klinik, Koeln (Germany))


    We present the case of a patient with a spondylolisthesis of L5 on S1 due to spondylolysis at the level L5/S1. The vertebral slip was fixed and no anterior instability was found. Using functional magnetic resonance imaging (MRI) in an upright MRI scanner, posterior instability at the level of the spondylolytic defect of L5 was demonstrated. A structure, probably the hypertrophic ligament flava, arising from the spondylolytic defect was displaced toward the L5 nerve root, and a bilateral contact of the displaced structure with the L5 nerve root was shown in extension of the spine. To our knowledge, this is the first case described of posterior instability in patients with spondylolisthesis. The clinical implications of posterior instability are unknown; however, it is thought that this disorder is common and that it can only be diagnosed using upright MRI.

  11. Intravenous flurbiprofen axetil can stabilize the hemodynamic instability due to mesenteric traction syndrome--evaluation with continuous measurement of the systemic vascular resistance index using a FloTrac® sensor. (United States)

    Takada, Motoshi; Taruishi, Chieko; Sudani, Tomoko; Suzuki, Akira; Iida, Hiroki


    Evaluation of the stabilizing effect of intravenous flurbiprofen axetil against hemodynamic instability due to mesenteric traction syndrome (MTS) by continuous measurement of systemic vascular resistance index (SVRI) using a FloTrac(®) sensor was evaluated. Prospective randomized trial. A single-center study performed in an educational hospital. Two prospective studies were carried out, each with 40 patients scheduled for elective open abdominal surgery. Twenty patients received 50 mg of flurbiprofen axetil after the recognition of MTS by the anesthesiologist (group FT). The remaining patients served as controls (groups CP and CT). SVRI data was collected every 20 seconds for 1 hour after starting the laparotomy. The average SVRI prior to skin incision was taken as the baseline. Following 3 values were devised to evaluate MTS: the S-value (sum total of changes in SVRI from baseline), the T-value (period during which SVRI remained 20% or more below baseline), and the M-value (maximum change in SVRI from baseline). In group FP, decrease in SVRI was smaller than in group CP, and statistical differences in the 3 values were found. In group FT, SVRI recovered earlier than in group CT, and statistical differences were found in S-value and T-value. However, the M-value had no statistical differences. Intravenous flurbiprofen axetil can stabilize the hemodynamic instability due to MTS. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. A discrete element model of laser beam induced current (LBIC) due to the lateral photovoltaic effect in open-circuit HgCdTe photodiodes

    Energy Technology Data Exchange (ETDEWEB)

    Fynn, K.A.; Faraone, L. [Univ. of Western Australia, Nedlands (Australia). Dept. of Electrical and Electronic Engineering; Bajaj, J. [Rockwell International Science Center, Thousand Oaks, CA (United States)


    The non-destructive optical characterization technique of Laser-Beam-Induced-Current (LBIC) imaging has proven useful in qualitatively assessing electrically active defects and localized non-uniformities in HgCdTe materials and devices used for infrared photovoltaic arrays. To further the development of a quantitative working model for LBIC, this paper focuses on the application of the technique to photovoltaic structures that are represented by a discrete element equivalent circuit. For this particular case the LBIC signal arises due to the lateral photovoltaic effect in non-uniformly illuminated open-circuit photodiodes. The outcomes of the model predict all of the experimentally observed geometrical features of the LBIC image and signal. Furthermore, the model indicates that the LBIC signal has an extremely weak dependence on the p-n junction reverse saturation current, and shows a linear dependence with laser power. This latter feature may be useful for non-contact measurement of the quantum efficiency of individual photodiodes within a large two-dimensional focal plane array. The decay of the LBIC signal outside the physical boundary of the p-n junction is of the same form as the roll-off in the short circuit photoresponse and, therefore, can be used to extract the diffusion length of minority carriers. Experimental data are obtained from an arsenic implanted p-on-n junction fabricated on MBE grown Hg{sub 1{minus}x}Cd{sub x}Te material with an x-value of 0.3. The p-on-n diode is shown to be uniform and of high quality with an R{sub o}A product of 1 {times} 10{sup 8} {Omega}{center_dot}cm{sup 2} at 77 K. The validity of the simple model developed in this paper, is confirmed by the excellent agreement with experimental results. Consequently, the LBIC technique is shown to be an appropriate diagnostic tool for non-contact quantitative analysis of semiconductor materials and devices.

  13. Mechanical instability

    CERN Document Server

    Krysinski, Tomasz


    This book presents a study of the stability of mechanical systems, i.e. their free response when they are removed from their position of equilibrium after a temporary disturbance. After reviewing the main analytical methods of the dynamical stability of systems, it highlights the fundamental difference in nature between the phenomena of forced resonance vibration of mechanical systems subjected to an imposed excitation and instabilities that characterize their free response. It specifically develops instabilities arising from the rotor-structure coupling, instability of control systems, the se

  14. Collective instabilities

    Energy Technology Data Exchange (ETDEWEB)

    K.Y. Ng


    The lecture covers mainly Sections 2.VIII and 3.VII of the book ''Accelerator Physics'' by S.Y. Lee, plus mode-coupling instabilities and chromaticity-driven head-tail instability. Besides giving more detailed derivation of many equations, simple interpretations of many collective instabilities are included with the intention that the phenomena can be understood more easily without going into too much mathematics. The notations of Lee's book as well as the e{sup jwt} convention are followed.

  15. Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

    Directory of Open Access Journals (Sweden)

    Bueno Clara


    , SHEF-1, which was maintained for 185 passages in feeders did not undergo any numerical or structural chromosomal change after 30 passages in feeder-free culture and over 215 passages in total. Conclusion These results support the concept that feeder-free conditions may partially contribute to hESC chromosomal changes but also confirm the hypothesis that regardless of the culture conditions, culture duration or splitting methods, some hESC lines are inherently more prone than others to karyotypic instability.

  16. C1-C2 transarticular screw fixation for atlantoaxial instability due to rheumatoid arthritis: a seven-year analysis of outcome.

    LENUS (Irish Health Repository)

    Nagaria, Jabir


    STUDY DESIGN.: Observational study. Retrospective analysis of prospectively collected data. OBJECTIVE.: The purpose of this article was to report long-term (minimum 7 years) clinical and radiologic outcome of our series of patients with Rheumatoid Arthritis who underwent transarticular screw fixation to treat atlantoaxial subluxation. SUMMARY OF BACKGROUND DATA.: The indications for intervention in patients with atlantoaxial instability are pain, myelopathy, and progressive neurologic deficit. The various treatment options available for these patients are isolated C1-C2 fusion, occipitocervical fusion with or without transoral surgery. Review of current literature suggests that C1-C2 transarticular screw fixation has significant functional benefits, although there is discrepancy in this literature regarding improvement in function following surgery. METHODS.: Myelopathy was assessed using Ranawat myelopathy score and Myelopathy Disability Index. Pain scores were assessed using Visual Analogue Scale. The radiologic imaging was assessed and the following data were extracted; atlanto-dens interval, space available for cord, presence of signal change on T2 weighted image, and fusion rates. RESULTS.: Thirty-seven patients, median age 56, were included in the study. Average duration of neck symptoms was 15.8 months. Average duration of rheumatoid arthritis before surgery was 20.6 years. Preoperative symptoms: suboccipital pain in 26 patients; neck pain, 32; myelopathy, 22; and 5 were asymptomatic. After surgery: suboccipital pain, 2; neck pain, 3; and myelopathy, 10. Ninety percent patients with neck and suboccipital pain improved after surgery in their Visual Analogue pain scores, with all of them having >50% improvement in VAS scores (6.94-2.12 [P < 0.05]).Preoperative Ranawat grade was as follows: grade 1 in 15 patients, grade 2 in 7, and grade 3a in 14, grade 3b in 1.After surgery: grade 1 in 27 patients, grade 2 in 7, grade 3a in 1, and grade 3b in 2. The mean

  17. Massive Rock Detachments from the Continental slope of the Balsas River Submarine Delta that occur due to Instability of Sediments which Produce Turbidity Currents and Tsunamis (United States)

    Sandoval-Ochoa, J.; Aguayo-Camargo, J.


    During the NOAA oceanographic delivery cruise of the US R/V "Roger Revelle" to the Scripps Institution of Oceanography at the University of California in San Diego, California USA, in July 1996; a well calibrated bathymetric equipment, the SeaBeam* 2012, was tested. Good resolutions in data allowed bathymetric mapping to visualize the sea floor relief. Detailed colorful chartographic images showed a portion of the continental slope between the Balsas River Delta and the Middle America Trench and between the Balsas Canyon and La Necesidad Canyon. The surveyed area covered more than 3 000 square kilometers. After the delivery cruise, one of the goals was to measure and analyze the Morphobathymetry of the uneven lower portion of the Balsas River Submarine Delta. So far some of the findings with the morphometric analyses consist of several isolated slump scars that each comprise more than 12 cubic kilometers in volume and a multiple slump scar with an evident steep hollow about 200 cubic kilometers absent of rock. These volumes of rock apparently underwent a remobilization from the slope during the Late Quaternary. The rock detachments occured in relatively small portions but in instantaneous massive displacements because of their instability as well as other identified factors in the region. Over time more and more authors have accepted that coastal cuts or submarine slump scars have been left by sudden movements of rock and fluids. The phenomena that occur in the region in general, are accompanied on one side by potential and kinetic energies like falling bodies, flows and gravity waves, and on the other side, by mass transfer of rock and fluid mobilization like turbidity currents, accumulations, sea wave surges or tsunamis. In some cases the phenomena is produced by another natural triggering forces or by an earthquake. We propose that events like these, i.e. massive detachments and their products such as accumulations, turbidity currents and depositional debrites

  18. Nanomechanical properties of lipid bilayer: Asymmetric modulation of lateral pressure and surface tension due to protein insertion in one leaflet of a bilayer (United States)

    Maftouni, Negin; Amininasab, Mehriar; Ejtehadi, Mohammad Reza; Kowsari, Farshad; Dastvan, Reza


    The lipid membranes of living cells form an integral part of biological systems, and the mechanical properties of these membranes play an important role in biophysical investigations. One interesting problem to be evaluated is the effect of protein insertion in one leaflet of a bilayer on the physical properties of lipid membrane. In the present study, an all atom (fine-grained) molecular dynamics simulation is used to investigate the binding of cytotoxin A3 (CTX A3), a cytotoxin from snake venom, to a phosphatidylcholine lipid bilayer. Then, a 5-microsecond coarse-grained molecular dynamics simulation is carried out to compute the pressure tensor, lateral pressure, surface tension, and first moment of lateral pressure in each monolayer. Our simulations reveal that the insertion of CTX A3 into one monolayer results in an asymmetrical change in the lateral pressure and corresponding spatial distribution of surface tension of the individual bilayer leaflets. The relative variation in the surface tension of the two monolayers as a result of a change in the contribution of the various intermolecular forces may potentially be expressed morphologically.

  19. Early in situ changes in chondrocyte biomechanical responses due to a partial meniscectomy in the lateral compartment of the mature rabbit knee joint. (United States)

    Fick, J M; P Ronkainen, A; Madden, R; Sawatsky, A; Tiitu, V; Herzog, W; Korhonen, R K


    We determined the biomechanical responses of chondrocytes to indentation at specific locations within the superficial zone of cartilage (i.e. patellar, femoral groove, femoral condylar and tibial plateau sites) taken from female New Zealand white rabbits three days after a partial meniscectomy in the lateral compartment of a knee joint. Confocal laser scanning microscopy combined with a custom indentation system was utilized to image chondrocyte responses at sites taken from ten contralateral and experimental knee joints. Cell volume, height, width and depth changes, global, local axial and transverse strains and Young׳s moduli were determined. Histological assessment was performed and proteoglycan content from the superficial zone of each site was determined. Relative to contralateral group cells, patellar, femoral groove and lateral femoral condyle cells in the experimental group underwent greater volume decreases (p volume decreases (p 0.05), femoral groove, medial femoral condyle and medial tibial plateau experimental sites (p < 0.05). The findings suggest: (i) cell biomechanical responses to cartilage loading in the rabbit knee joint can become altered as early as 3 days after a partial meniscectomy, (ii) are site-specific, and (iii) occur before alterations in tissue mechanics or changes detectable with histology.

  20. Recombination instability

    DEFF Research Database (Denmark)

    D'Angelo, N.


    A recombination instability is considered which may arise in a plasma if the temperature dependence of the volume recombination coefficient, alpha, is sufficiently strong. Two cases are analyzed: (a) a steady-state plasma produced in a neutral gas by X-rays or high energy electrons; and (b) an af...

  1. Gravitational Instabilities in Circumstellar Disks (United States)

    Kratter, Kaitlin; Lodato, Giuseppe


    Star and planet formation are the complex outcomes of gravitational collapse and angular momentum transport mediated by protostellar and protoplanetary disks. In this review, we focus on the role of gravitational instability in this process. We begin with a brief overview of the observational evidence for massive disks that might be subject to gravitational instability and then highlight the diverse ways in which the instability manifests itself in protostellar and protoplanetary disks: the generation of spiral arms, small-scale turbulence-like density fluctuations, and fragmentation of the disk itself. We present the analytic theory that describes the linear growth phase of the instability supplemented with a survey of numerical simulations that aim to capture the nonlinear evolution. We emphasize the role of thermodynamics and large-scale infall in controlling the outcome of the instability. Despite apparent controversies in the literature, we show a remarkable level of agreement between analytic predictions and numerical results. In the next part of our review, we focus on the astrophysical consequences of the instability. We show that the disks most likely to be gravitationally unstable are young and relatively massive compared with their host star, Md/M*≥0.1. They will develop quasi-stable spiral arms that process infall from the background cloud. Although instability is less likely at later times, once infall becomes less important, the manifestations of the instability are more varied. In this regime, the disk thermodynamics, often regulated by stellar irradiation, dictates the development and evolution of the instability. In some cases the instability may lead to fragmentation into bound companions. These companions are more likely to be brown dwarfs or stars than planetary mass objects. Finally, we highlight open questions related to the development of a turbulent cascade in thin disks and the role of mode-mode coupling in setting the maximum angular


    Directory of Open Access Journals (Sweden)

    Ionescu Cristian


    Full Text Available There is an important link between the following two variables: financial instability and political instability. Often, the link is bidirectional, so both may influence each other. This is way the lately crisis are becoming larger and increasingly complex. Therefore, the academic environment is simultaneously talking about economic crises, financial crises, political crises, social crises, highlighting the correlation and causality between variables belonging to the economic, financial, political and social areas, with repercussions and spillover effects that extend from one area to another. Given the importance, relevance and the actuality of the ones described above, I consider that at least a theoretical analysis between economic, financial and political factors is needed in order to understand the reality. Thus, this paper aims to find links and connections to complete the picture of the economic reality.

  3. Selective hemiepiphyseodesis for patellar instability with associated genu valgum. (United States)

    Kearney, Sean P; Mosca, Vincent S


    Patellar instability limits activity and promotes arthritis. Correcting genu valgum with selective hemiepiphyseodesis can treat patellar instability. We retrospectively reviewed 26 knees with patellar instability and associated genu valgum that underwent hemiepiphyseodesis. Average anatomic lateral distal femoral angle (aLDFA) significantly corrected. Symptoms improved in all patients. All competitive athletes returned to sports. One complication occurred. In genu valgum, the patella seeks an abnormal mechanical axis, resulting in patellar instability. By correcting the mechanical axis with hemiepiphyseodesis, patellar instability symptoms improve and patients return to sports. Complications are rare. Selective hemiepiphyseodesis is recommended when treating patellar instability with associated genu valgum.

  4. Microphysics of cosmic ray driven plasma instabilities

    CERN Document Server

    Bykov, A M; Malkov, M A; Osipov, S M


    Energetic nonthermal particles (cosmic rays, CRs) are accelerated in supernova remnants, relativistic jets and other astrophysical objects. The CR energy density is typically comparable with that of the thermal components and magnetic fields. In this review we discuss mechanisms of magnetic field amplification due to instabilities induced by CRs. We derive CR kinetic and magnetohydrodynamic equations that govern cosmic plasma systems comprising the thermal background plasma, comic rays and fluctuating magnetic fields to study CR-driven instabilities. Both resonant and non-resonant instabilities are reviewed, including the Bell short-wavelength instability, and the firehose instability. Special attention is paid to the longwavelength instabilities driven by the CR current and pressure gradient. The helicity production by the CR current-driven instabilities is discussed in connection with the dynamo mechanisms of cosmic magnetic field amplification.

  5. Magnetorotational Instability in Liquid Metal Couette Flow

    CERN Document Server

    Noguchi, K; Colgate, S A; Nordhaus, J; Beckley, H F


    Despite the importance of the magnetorotational instability (MRI) as a fundamental mechanism for angular momentum transport in magnetized accretion disks, it has yet to be demonstrated in the laboratory. A liquid sodium alpha-omega dynamo experiment at the New Mexico Institute of Mining and Technology provides an ideal environment to study the MRI in a rotating metal annulus (Couette flow). A local stability analysis is performed as a function of shear, magnetic field strength, magnetic Reynolds number, and turbulent Prandtl number. The later takes into account the minimum turbulence induced by the formation of an Ekman layer against the rigidly rotating end walls of a cylindrical vessel. Stability conditions are presented and unstable conditions for the sodium experiment are compared with another proposed MRI experiment with liquid gallium. Due to the relatively large magnetic Reynolds number achievable in the sodium experiment, it should be possible to observe the excitation of the MRI for a wide range of w...

  6. Marital instability after midlife. (United States)

    Wu, Z; Penning, M J


    "Divorce in later life has been shown to produce dramatic declines in the economic, psychological, and physical well-being of marital partners. This study examines the prevalence and determinants of marital disruption after midlife using Becker's theory of marital instability. Using recent Canadian national data, the marital outcomes of women and men who were married as of age 40 are tracked across the remaining years of the marriage. Cox proportional hazard regression models indicate stabilizing effects of the duration of the marriage, the age at first marriage, the presence of young children, as well as of remarriage for middle-aged and older persons. Other significant risk factors include education, heterogamous marital status, premarital cohabitation, number of siblings, and region."

  7. Moment Contribution Capacity of Tendon Prestressed Partial on Concrete Beam-column Joint Interior According to Provisions ACI 318-2008 Chapter Due to Cyclic Lateral Loads

    Directory of Open Access Journals (Sweden)

    Astawa Made Dharma


    Full Text Available This research designed a partial prestressed concrete beam-column with reinforced concrete interior joint, using square columns of 400/400 mm, reinforcement 6 D16 + 4D13, section beam 250/400 mm, tensile reinforcement 5 D13, compression reinforcement 3 D13 + 2 strand tendon D12,7 mm , and joint without plastic hinge, then tested in laboratory with lateral cyclic loads on peak column, static axial load 1120 kN on the centre column, to get the tendon capacity to assume positive and negative bending moments due to lateral load, according to provisions of ACI 318-2008 part (c. Test results showed that the moment tendon contribution on beam section, in the tensile area, the positive and negative moment both on the left side or the right side column are all qualified ( 25 %. As for the negative moment, either left or right side column are all qualified (4.0. Although the contribution of positive moment capacity tendon in compression areas does not qualify, in overall, the reliability and ductility of the structure qualify.

  8. Capillary Instability in Nanoimprinted Polymer Films

    Energy Technology Data Exchange (ETDEWEB)

    Alvine, Kyle J.; Ding, Yifu; Douglas, Jack F.; Ro, Hyun W.; Okerberg, Brian C.; Karim, Alamgir; Soles, Christopher L.


    Capillary forces play an active role in defining the equilibrium structure of nanoscale structures. This effect can be especially pronounced in soft materials such as polymers near or above their glass transition temperature Tg where material flow is possible. In these situations, the effect of surface tension can produce varied and complex capillary instabilities, even in relatively simple geometries such as parallel line-space grating patterns. Here we investigate a novel capillary instability that arises in polystyrene line-space gratings with a residual layer connecting these structures (created by nanoimprint lithography) upon thermal annealing of these patterns. This novel instability is characterized by the development of lateral undulations of the lines that culminates in the local coalescence of adjacent imprinted lines. An exact analytic model of this undulatory instability is not possible, but we introduce a simple physical model for this lateral instability based on the driving force to reduce the surface energy, as in the well-known Rayleigh-Plateau instability which is likewise surface energy driven. Good agreement is obtained between this simplified model and our observations. Our insights into the nature of this instability have implications for controlling the thermal stability of nanoscale patterns made by nanoimprint lithography or other lithography techniques.

  9. Shoulder instability; Schultergelenkinstabilitaet

    Energy Technology Data Exchange (ETDEWEB)

    Sailer, J.; Imhof, H. [Abteilung Osteoradiologie, Univ.-Klinik fuer Radiodiagnostik Wien (Austria)


    Shoulder instability is a common clinical feature leading to recurrent pain and limitated range of motion within the glenohumeral joint. Instability can be due a single traumatic event, general joint laxity or repeated episodes of microtrauma. Differentiation between traumatic and atraumatic forms of shoulder instability requires careful history and a systemic clinical examination. Shoulder laxity has to be differentiated from true instability followed by the clinical assessment of direction and degree of glenohumeral translation. Conventional radiography and CT are used for the diagnosis of bony lesions. MR imaging and MR arthrography help in the detection of soft tissue affection, especially of the glenoid labrum and the capsuloligamentous complex. The most common lesion involving the labrum is the anterior labral tear, associated with capsuloperiostal stripping (Bankart lesion). A number of variants of the Bankart lesion have been described, such as ALPSA, SLAP or HAGL lesions. The purpose of this review is to highlight different forms of shoulder instability and its associated radiological findings with a focus on MR imaging. (orig.) [German] Die Schultergelenkinstabilitaet ist haeufig fuer wiederholt auftretende Schmerzen sowie eine eingeschraenkte Beweglichkeit im Glenohumeralgelenk verantwortlich. Sie kann als Folge eines vorangegangenen Traumas, einer generellen Hyperlaxitaet oder infolge wiederholter Mikrotraumen entstehen. Die Differenzierung zwischen traumatischer und atraumatischer Form der Gelenkinstabilitaet erfordert eine sorgfaeltige Anamnese und eine genaue klinische Untersuchung. Die Gelelenklaxitaet als Differenzialdiagnose muss von der echten Instabilitaet unterschieden werden, die Instabilitaet wird dann im Rahmen des klinischen Status nach Grad und Richtung der glenohumeralen Translation unterteilt. Zur Diagnose knoecherner Laesionen werden das konventionelle Roentgen sowie die CT herangezogen. MRT sowie MR-Arthrographie dienen zur Detektion

  10. Transverse Instabilities in the Fermilab Recycler

    Energy Technology Data Exchange (ETDEWEB)

    Prost, L.R.; Burov, A.; Shemyakin, A.; Bhat, C.M.; Crisp, J.; Eddy, N.; /Fermilab


    Transverse instabilities of the antiproton beam have been observed in the Recycler ring soon after its commissioning. After installation of transverse dampers, the threshold for the instability limit increased significantly but the instability is still found to limit the brightness of the antiprotons extracted from the Recycler for Tevatron shots. In this paper, we describe observations of the instabilities during the extraction process as well as during dedicated studies. The measured instability threshold phase density agrees with the prediction of the rigid beam model within a factor of 2. Also, we conclude that the instability threshold can be significantly lowered for a bunch contained in a narrow and shallow potential well due to effective exclusion of the longitudinal tails from Landau damping.

  11. Lateral Concepts

    Directory of Open Access Journals (Sweden)

    Christopher Gad


    Full Text Available This essay discusses the complex relation between the knowledges and practices of the researcher and his/her informants in terms of lateral concepts. The starting point is that it is not the prerogative of the (STS scholar to conceptualize the world; all our “informants” do it too. This creates the possibility of enriching our own conceptual repertoires by letting them be inflected by the concepts of those we study. In a broad sense, the lateral means that there is a many-to-many relation between domains of knowledge and practice. However, each specific case of the lateral is necessarily immanent to a particular empirical setting and form of inquiry. In this sense lateral concepts are radically empirical since it locates concepts within the field. To clarify the meaning and stakes of lateral concepts, we first make a contrast between lateral anthropology and Latour’s notion of infra-reflexivity. We end with a brief illustration and discussion of how lateral conceptualization can re-orient STS modes of inquiry, and why this matters.

  12. Less invasive corrective surgery using oblique lateral interbody fusion (OLIF) including L5-S1 fusion for severe lumbar kyphoscoliosis due to L4 compression fracture in a patient with Parkinson's disease: a case report. (United States)

    Wakita, Hiromasa; Shiga, Yasuhiro; Ohtori, Seiji; Kubota, Go; Inage, Kazuhide; Sainoh, Takeshi; Sato, Jun; Fujimoto, Kazuki; Yamauchi, Kazuyo; Nakamura, Junichi; Takahashi, Kazuhisa; Toyone, Tomoaki; Aoki, Yasuchika; Inoue, Gen; Miyagi, Masayuki; Orita, Sumihisa


    Corrective surgery for kyphoscoliosis patients tend to be highly invasive due to osteotomy. The present case introduce less invasive corrective surgery using anterior oblique lateral interbody fusion (OLIF) technique. An 80-year-old Japanese man with a history of Parkinson's disease presented to our hospital because of severe kyphoscoliosis and gait disturbance. Considering the postsurgical complications due to osteotomy, we performed an anterior-posterior combined corrective fusion surgery: OLIF of Lumbar (L) 2-3, L3-4, and L4-5 (Medtronic Sofamor Danek, Memphis, TN, USA) followed by L5-Sacral (S) 1 anterior lumbar fusion via the OLIF approach using an anterior intervertebral cage, and posterior L3-4 and L4-5 facetectomy and posterior fusion using percutaneous pedicle screws from Thoracic (T) 10 to S1 with a T-9 hook system. The surgery was performed in a less invasive manner with no osteotomy, and it improved the sagittal alignments with moderate restoration, which improved the patient's posture and gait disturbance. The patient showed transient muscle weakness of proximal lower extremity contralateral side to the surgical site, which fully recovered by physical rehabilitation 3 months after the surgery. The surgical corrective procedure using the minimally invasive OLIF method including L5-S1 fusion showed a great advantage in treating degenerative kyphoscoliosis in a Parkinson's disease patient in its less-invasive approac.

  13. Electron heat flux instability (United States)

    Saeed, Sundas; Sarfraz, M.; Yoon, P. H.; Lazar, M.; Qureshi, M. N. S.


    The heat flux instability is an electromagnetic mode excited by a relative drift between the protons and two-component core-halo electrons. The most prominent application may be in association with the solar wind where drifting electron velocity distributions are observed. The heat flux instability is somewhat analogous to the electrostatic Buneman or ion-acoustic instability driven by the net drift between the protons and bulk electrons, except that the heat flux instability operates in magnetized plasmas and possesses transverse electromagnetic polarization. The heat flux instability is also distinct from the electrostatic counterpart in that it requires two electron species with relative drifts with each other. In the literature, the heat flux instability is often called the 'whistler' heat flux instability, but it is actually polarized in the opposite sense to the whistler wave. This paper elucidates all of these fundamental plasma physical properties associated with the heat flux instability starting from a simple model, and gradually building up more complexity towards a solar wind-like distribution functions. It is found that the essential properties of the instability are already present in the cold counter-streaming electron model, and that the instability is absent if the protons are ignored. These instability characteristics are highly reminiscent of the electron firehose instability driven by excessive parallel temperature anisotropy, propagating in parallel direction with respect to the ambient magnetic field, except that the free energy source for the heat flux instability resides in the effective parallel pressure provided by the counter-streaming electrons.

  14. Patellar instability treated with distal femoral osteotomy. (United States)

    Swarup, Ishaan; Elattar, Osama; Rozbruch, S Robert


    Patellar instability can cause significant disability in both pediatric and adult patients, and it is associated with several factors including genu valgum. In this study, we describe the role of a lateral opening wedge distal femoral osteotomy (DFO) combined with lateral retinacular release in addressing genu valgum with associated patellar instability. The rationale for this approach is to medialize the patellar tendon insertion and decrease the Q angle with DFO. A consecutive series of patients were studied, and our outcomes of interest included improvements in radiographic measures and patient outcomes. Radiographic improvement was assessed using patella congruency angle (PCA), mechanical axis deviation (MAD), and lateral distal femoral angle (LDFA). Patient outcomes were assessed using Oxford Knee scores, KOOS-PS scores, VAS pain scores, and Kujala scores. We studied eight patients (10 knees) that underwent a lateral opening wedge DFO for genu valgum and patellar instability. Mean follow-up duration was 27 months. PCA improved from 30.4° lateral preoperatively to 5.7° lateral postoperatively (p=0.016). Similarly, MAD improved from 33.1mm lateral to 6.5mm medial, and LDFA improved from 82.4° to 92.7° after surgery (p=0.002). There were significant improvements in VAS pain and Kujala scores after surgery (pgenu valgum. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Evaluating shoulder instability treatment

    NARCIS (Netherlands)

    van der Linde, J.A.


    Shoulder instability common occurs. When treated nonoperatively, the resulting societal costs based on health care utilization and productivity losses are significant. Shoulder function can be evaluated using patient reported outcome measurements (PROMs). For shoulder instability, these include the

  16. Jeans instability in superfluids

    Energy Technology Data Exchange (ETDEWEB)

    Hason, Itamar; Oz, Yaron [Tel-Aviv University, Raymond and Beverly Sackler School of Physics and Astronomy, Tel Aviv (Israel)


    We analyze the effect of a gravitational field on the sound modes of superfluids. We derive an instability condition that generalizes the well-known Jeans instability of the sound mode in normal fluids. We discuss potential experimental implications. (orig.)

  17. Radiation Induced Genomic Instability

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, William F.


    Radiation induced genomic instability can be observed in the progeny of irradiated cells multiple generations after irradiation of parental cells. The phenotype is well established both in vivo (Morgan 2003) and in vitro (Morgan 2003), and may be critical in radiation carcinogenesis (Little 2000, Huang et al. 2003). Instability can be induced by both the deposition of energy in irradiated cells as well as by signals transmitted by irradiated (targeted) cells to non-irradiated (non-targeted) cells (Kadhim et al. 1992, Lorimore et al. 1998). Thus both targeted and non-targeted cells can pass on the legacy of radiation to their progeny. However the radiation induced events and cellular processes that respond to both targeted and non-targeted radiation effects that lead to the unstable phenotype remain elusive. The cell system we have used to study radiation induced genomic instability utilizes human hamster GM10115 cells. These cells have a single copy of human chromosome 4 in a background of hamster chromosomes. Instability is evaluated in the clonal progeny of irradiated cells and a clone is considered unstable if it contains three or more metaphase sub-populations involving unique rearrangements of the human chromosome (Marder and Morgan 1993). Many of these unstable clones have been maintained in culture for many years and have been extensively characterized. As initially described by Clutton et al., (Clutton et al. 1996) many of our unstable clones exhibit persistently elevated levels of reactive oxygen species (Limoli et al. 2003), which appear to be due dysfunctional mitochondria (Kim et al. 2006, Kim et al. 2006). Interestingly, but perhaps not surprisingly, our unstable clones do not demonstrate a “mutator phenotype” (Limoli et al. 1997), but they do continue to rearrange their genomes for many years. The limiting factor with this system is the target – the human chromosome. While some clones demonstrate amplification of this chromosome and thus lend

  18. Collision and recombination driven instabilities in variable charged dusty plasmas

    Indian Academy of Sciences (India)

    S Bal; M Bose


    The dust-acoustic instability driven by recombination of electrons and ions on the surface of charged and variably-charged dust grains as well as by collisions in dusty plasmas with significant pressure of background neutrals have been theoretically investigated. The recombination driven instability is shown to be dominant in the long wavelength regime even in the presence of dust-neutral and ion-neutral collisions, while in the shorter wavelength regime, the dust-neutral collision is found to play a major role. In an earlier research work, the dust-neutral collision was neglected in comparison to the effect due to the recombination for estimating the dust-acoustic instability; later the other report shows that the recombination effect is negligible in the presence of dust-neutral collisions. In line of this present situation our investigation revealed that the recombination is more important than dust-neutral collisions in laboratory plasma and fusion plasma, while the dust-neutral collision frequency is dominant in the interstellar plasmas. The effects of ion and dust densities and ion streaming on the recombination and collision driven mode in parameter regimes relevant for many experimental studies on dusty plasmas have also been calculated.

  19. Correlation of OPLL with spinal instability

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ho Chul; Chung, Tae Sub; Kim, Young Soo [Yonsei Univ. College of Medicine, Seoul (Korea, Republic of)


    To evaluate the relationship between spinal instability and ossification of the posterior longitudinal ligament(OPLL). Materials and Methods: In 70 patients(M:F=45:25, mean age=53 years) diagnosed as OPLL on the basis of surgical operation field findings and radiological evaluation [plain film(n=70), CT(n=64),MRI(n=55)], involved levels were the cervical spine(n=32), lumbar spine(n=23), and both the cervical and lumbar spine(n=15). Spinal instability was radiologically diagnosed as horizontal displacement of one vertebra by another of more than 3.5 mm, or a difference in rotation from either adjacent vertebra by more than 11 degree in lateral cervical spine and a difference of more than 1.5 mm from the posterior body margins to the point of intersection of two lines drawn parallel to the opposing segmental endplate in extension lateral lumbar spine. We divided OPLL into group I(continuous, segmental, mixed) and group II(retrodiscal), and compared spinal instability in these two groups. Results: In cervical OPLL, group I comprised 33 cases and group II 14. In group I, spinal instability was noted in 8/33 cases(24%) or 10/123 segments(8.1%). Spinal instability in group II, on the other hand, was found in 13/14 cases(93%) or 17/26 segments(65%). Ossification occurred at the retrodiscal level in 37 cases, byt in case was continuous. In group II, spinal instability was found in 25 of 37 cases(69%), oe in 29 of 55 segments(53%). Conclusion: Compared to other types of OPLL, the frequency of retrodiscal OPLL in association with spinal instability was high. Spinal instability may thus be the most important cause of retrodiscal OPLL.

  20. Telomere dysfunction and chromosome instability

    Energy Technology Data Exchange (ETDEWEB)

    Murnane, John P., E-mail: [Department of Radiation Oncology, University of California San Francisco, 2340 Sutter Street, San Francisco, CA 94143-1331 (United States)


    The ends of chromosomes are composed of a short repeat sequence and associated proteins that together form a cap, called a telomere, that keeps the ends from appearing as double-strand breaks (DSBs) and prevents chromosome fusion. The loss of telomeric repeat sequences or deficiencies in telomeric proteins can result in chromosome fusion and lead to chromosome instability. The similarity between chromosome rearrangements resulting from telomere loss and those found in cancer cells implicates telomere loss as an important mechanism for the chromosome instability contributing to human cancer. Telomere loss in cancer cells can occur through gradual shortening due to insufficient telomerase, the protein that maintains telomeres. However, cancer cells often have a high rate of spontaneous telomere loss despite the expression of telomerase, which has been proposed to result from a combination of oncogene-mediated replication stress and a deficiency in DSB repair in telomeric regions. Chromosome fusion in mammalian cells primarily involves nonhomologous end joining (NHEJ), which is the major form of DSB repair. Chromosome fusion initiates chromosome instability involving breakage-fusion-bridge (B/F/B) cycles, in which dicentric chromosomes form bridges and break as the cell attempts to divide, repeating the process in subsequent cell cycles. Fusion between sister chromatids results in large inverted repeats on the end of the chromosome, which amplify further following additional B/F/B cycles. B/F/B cycles continue until the chromosome acquires a new telomere, most often by translocation of the end of another chromosome. The instability is not confined to a chromosome that loses its telomere, because the instability is transferred to the chromosome donating a translocation. Moreover, the amplified regions are unstable and form extrachromosomal DNA that can reintegrate at new locations. Knowledge concerning the factors promoting telomere loss and its consequences is

  1. Relativistic Gravothermal Instabilities

    CERN Document Server

    Roupas, Zacharias


    The thermodynamic instabilities of the self-gravitating, classical ideal gas are studied in the case of static, spherically symmetric configurations in General Relativity taking into account the Tolman-Ehrenfest effect. One type of instabilities is found at low energies, where thermal energy becomes too weak to halt gravity and another at high energies, where gravitational attraction of thermal pressure overcomes its stabilizing effect. These turning points of stability are found to depend on the total rest mass $\\mathcal{M}$ over the radius $R$. The low energy instability is the relativistic generalization of Antonov instability, which is recovered in the limit $G\\mathcal{M} \\ll R c^2$ and low temperatures, while in the same limit and high temperatures, the high energy instability recovers the instability of the radiation equation of state. In the temperature versus energy diagram of series of equilibria, the two types of gravothermal instabilities make themselves evident as a double spiral! The two energy l...

  2. Results of Latarjet Coracoid Transfer to Revise Failed Arthroscopic Instability Repairs (United States)

    Nicholson, Gregory P.; Rahman, Zain; Verma, Nikhil N.; Romeo, Anthony A.; Cole, Brian J.; Gupta, Anil Kumar; Bruce, Benjamin


    Objectives: Arthroscopic instability repair has supplanted open techniques to anatomically reconstruct anteroinferior instability pathology. Arthroscopic technique can fail for a variety of reasons. We have utilized the Latarjet as a revision option in failed arthroscopic instability repairs when there is altered surgical anatomy, capsular deficiency and/or glenoid bone compromise and recurrent glenohumeral instability. Methods: We reviewed 51 shoulders (40 ♀, 11♂) that underwent Latarjet coracoid transfer for the revision of failed previous arthroscopic instability repair. The avg. age was 32.6 yrs (16-58). All patients had recurrent symptomatic anterior instability after previous arthroscopic surgery, and avg. time from arthroscopic repair to Latarjet was 13 months (4-40 mn). All had either CT or MRI that revealed suture anchor material in the glenoid, labral and capsular stripping, and anteroinferior glenoid bone loss or erosion. Advanced bone loss percentage analysis was not performed for this study. We excluded all patients that had a previous open repair, a seizure disorder, or if the Latarjet was a primary procedure. Outcome scores pre-operatively avg: SST: 6.7 (1-12); VAS: 3 (0-8); ASES: 63 (32-89). Coracoid transfer was performed thru a subscapularis split in 38, and with tendon takedown in 13. The coracoid was osteotomized along its long axis parallel to the undersurface of the lateral aspect. This provided at least 2.5 to 3.5 cm of graft with the conjoined tendon attached. The coracoacromial (CA) ligament was incised leaving a 1 cm. stump. The transfer was affixed flush with the articular surface but not lateral to it, with two 3.5 mm cortical screws in lag fashion overdrilling the coracoid with the CA ligament directed laterally. The capsule was then repaired to the CA ligament to make the transfer extra-articular. Results: At avg. 4 yr (2-7 yrs) follow-up stability had been maintained in 51 (100%).without further instability surgery. There were no

  3. The subcritical baroclinic instability in local accretion disc models

    CERN Document Server

    Lesur, G


    (abridged) Aims: We present new results exhibiting a subcritical baroclinic instability (SBI) in local shearing box models. We describe the 2D and 3D behaviour of this instability using numerical simulations and we present a simple analytical model describing the underlying physical process. Results: A subcritical baroclinic instability is observed in flows stable for the Solberg-Hoiland criterion using local simulations. This instability is found to be a nonlinear (or subcritical) instability, which cannot be described by ordinary linear approaches. It requires a radial entropy gradient weakly unstable for the Schwartzchild criterion and a strong thermal diffusivity (or equivalently a short cooling time). In compressible simulations, the instability produces density waves which transport angular momentum outward with typically alpha<3e-3, the exact value depending on the background temperature profile. Finally, the instability survives in 3D, vortex cores becoming turbulent due to parametric instabilities...

  4. Lateral Mixing (United States)


    being made on their analysis. A process we became very curious about was the separation of tendrils of warm salty water from the north wall figure 7...structure, and to remove the effect of internal waves by mapping this structure onto isopycnals. This has been very successful in elucidating lateral...we passed through the same water on multiple passes, and that changes in the horizontal structure of the water mas should be readily apparent from

  5. Shoulder instability; Schulterinstabilitaeten

    Energy Technology Data Exchange (ETDEWEB)

    Kreitner, Karl-Friedrich [Mainiz Univ. (Germany). Klinik und Poliklinik fuer Diagnostische und Interventionelle Radiologie


    In the shoulder, the advantages of range of motion are traded for the disadvantages of vulnerability to injury and the development of instability. Shoulder instability and the lesion it produces represent one of the main causes of shoulder discomfort and pain. Shoulder instability is defined as a symptomatic abnormal motion of the humeral head relative to the glenoid during active shoulder motion. Glenohumeral instabilities are classified according to their causative factors as the pathogenesis of instability plays an important role with respect to treatment options: instabilities are classified in traumatic and atraumatic instabilities as part of a multidirectional instability syndrome, and in microtraumatic instabilities. Plain radiographs ('trauma series') are performed to document shoulder dislocation and its successful reposition. Direct MR arthrography is the most important imaging modality for delineation the different injury patterns on the labral-ligamentous complex and bony structures. Monocontrast CT-arthrography with use of multidetector CT scanners may be an alternative imaging modality, however, regarding the younger patient age, MR imaging should be preferred in the diagnostic work-up of shoulder instabilities. (orig.)

  6. C2 Pedicle Screw Combined with C3 Lateral Mass Screw Fixation for Treatment of Instable Hangman's Fracture%C2椎弓根螺钉联合C3侧块螺钉固定治疗不稳定性Hangman骨折

    Institute of Scientific and Technical Information of China (English)

    杨国进; 章筛林; 石志才


    Objective To evaluate the surgical management and result of C2 pedicle screw combined with C3 lateral mass screw fixation for treatment of instable Hangman's fracture. Methods From August 2005 to December 2010,16 patients with instable Hangman's fracture were all treated with C2 pedicle screw combined with C3 lateral mass screw fixation,which involved 11 males and 5 females with an average age of 35. 4 years old (range 19- 59). According to Levine-Edwards classification ,11 cases were type Ⅰ ,5 cases were type Ⅱ a,2 cases were type Ⅲ . All the patients complained neck pain and limitation of cervical movement. There were D spinal injury in 3 cases and E in 13 cases according to Frankel scale. Results All patients were followed up for a mean time of 13. 5 months (range 9~36 months). The operative time was 95~170 min (average 114 min) and the blood loss was 290~450 mL(average 353 mL). All fractures healed at 6 months postoperatively. There was no internal fixation fracture or loosing occurred. The cervical movement was excellent. Three cases of grade D spinal injury recovered to grade E. Conclusion C2 pedicle screw combined with C3 lateral mass screw fixation is an effective method for treatment of instable Hangman's fracture.%目的 探讨C2椎弓根螺钉联合C3侧块螺钉内固定治疗不稳定性Hangman骨折的临床效果及应用价值.方法 2005年8月至2010年12月采用后路C2椎弓根螺钉联合C3侧块螺钉内固定治疗16例不稳定性Hangman骨折患者,男11例,女5例;年龄19~59岁,平均35.4岁.骨折按Levine-Edwards分类,Ⅱ型9例,Ⅱa型5例,Ⅲ型2例.脊髓损伤按Frankel分级,D级3例,E级13例.结果 所有患者均获随访,随访时间9~36个月(平均18个月).手术时间95~170 min(平均114 min),术中出血290~450 mL(平均353mL),术后6个月复查时,骨折均愈合,无断钉、断棒及螺钉松动发生,颈部活动功能恢复良好.脊髓功能D级3例均恢复至E级.结论 经后路C2

  7. Shock initiated instabilities in underwater cylindrical structures (United States)

    Gupta, Sachin; Matos, Helio; LeBlanc, James M.; Shukla, Arun


    An experimental investigation to understand the mechanisms of dynamic buckling instability in cylindrical structures due to underwater explosive loadings is conducted. In particular, the effects of initial hydrostatic pressure coupled with a dynamic pressure pulse on the stability of metallic cylindrical shells are evaluated. The experiments are conducted at varying initial hydrostatic pressures, below the critical buckling pressure, to estimate the threshold after which dynamic buckling will initiate. The transient underwater full-field deformations of the structures during shock wave loading are captured using high-speed stereo photography coupled with modified 3-D Digital Image Correlation (DIC) technique. Experimental results show that increasing initial hydrostatic pressure decreases the natural vibration frequency of the structure indicating loss in structural stiffness. DIC measurements reveal that the initial structural excitations primarily consist of axisymmetric vibrations due to symmetrical shock wave loading in the experiments. Following their decay after a few longitudinal reverberations, the primary mode of vibration evolves which continues throughout later in time. At the initial hydrostatic pressures below the threshold value, these vibrations are stable in nature. The analytical solutions for the vibration frequency and the transient response of cylindrical shell are discussed in the article by accounting for both (1) the added mass effect of the surrounding water and (2) the effect of initial stress on the shell imposed by the hydrostatic pressure. The analytical solutions match reasonably well with the experimental vibration frequencies. Later, the transient response of a cylindrical shell subjected to a general underwater pressure wave loading is derived which leads to the analytical prediction of dynamic stability.

  8. Shoulder Bankart lesion with posterior instability: A case report of ultrasound detection. (United States)

    Arai, Ryuzo; Ito, Taisuke; Okudaira, Shuzo; Matsuda, Shuichi


    Minor instability of the shoulder has recently drawn attention as a cause of shoulder pain in athletes. However, it is difficult to correctly diagnose the direction in which the humeral head translates and subluxates, and to clarify the pathology of the instability. We present a case of a 20-year-old male with an unstable shoulder who could not raise his left arm due to pain. Since 6 years prior to the onset of pain, the patient could asymptomatically perform voluntary subluxation, but it was slight and the direction of the subluxation could not be confirmed. On physical examination, the conventional apprehension test and Castagna test were positive, but the jerk test was negative. Imaging studies including arthroscopy showed a Bankart lesion associated with anterior labrum detachment. There was no posterior Bankart lesion. Due to painful anterior shoulder instability, arthroscopic Bankart repair was successfully done; however, 9 months later the patient began experiencing symptomatic subluxation of the shoulder. At this time, the conventional apprehension test and Castagna test were both negative. It was difficult to detect the direction of the subluxation, just like in the preoperative condition. We performed an ultrasonographic examination from the posterior side; this clearly revealed the posterior subluxation mechanism as posterior slide of the humeral head and anterior shift of the glenoid. Based on these findings, we modified the rehabilitation and the subluxation resolved. This case suggests that ultrasound imaging can be an effective practical option for evaluating shoulder instability, especially in cases of slight posterior subluxation.

  9. Weibel instability in relativistic quantum plasmas (United States)

    Mendonça, J. T.; Brodin, G.


    Generation of quasi-static magnetic fields, due to the Weibel instability is studied in a relativistic quantum plasma. This instability is induced by a temperature anisotropy. The dispersion relation and growth rates for low frequency electromagnetic perturbations are derived using a wave-kinetic equation which describes the evolution of the electron Wigner quasi-distribution. The influence of parallel kinetic effects is discussed in detail.

  10. Analysis on The Dam Flood Routing Due to Rainfall infiltration leads to Slope Instability%降雨入渗导致坝坡失稳时溃坝洪水演进分析

    Institute of Scientific and Technical Information of China (English)



    Using GeoStudio software analyzes the stability of The reservoir under the condition of rain infiltra-tion,and point the cause of the reservoir dam slope instability from a technical ,then,combination of Breach and River2D software simulation of the reservoir dam in flood routing.To a certain extent ,the analysis of sta-bility and flood routing can provide referential basis for the dam safety management of contingency plans.ser-vice for the reservoir management.%以GeoStudio软件分析某水库在降雨入渗情况下的稳定, 从技术角度剖析水库坝坡失稳的原因, 结合Breach和River2D软件模拟水库溃坝洪水演进. 在一定程度上, 稳定分析和洪水演进分析为水库管理单位制定大坝安全管理应急预案提供了依据.

  11. [Capsular retensioning in anterior unidirectional glenohumeral instability]. (United States)

    Benítez Pozos, Leonel; Martínez Molina, Oscar; Castañeda Landa, Ezequiel


    To present the experience of the Orthopedics Service PEMEX South Central Hospital in the management of anterior unidirectional shoulder instability with an arthroscopic technique consisting of capsular retensioning either combined with other anatomical repair procedures or alone. Thirty-one patients with anterior unidirectional shoulder instability operated-on between January 1999 and December 2005 were included. Fourteen patients underwent capsular retensioning and radiofrequency, and in 17 patients, capsular retensioning was combined with suture anchors. Patients with a history of relapsing glenohumeral dislocations and subluxations, with anterior instability with or without associated Bankart lesions were selected; all of them were young. The results were assessed considering basically the occurrence of instability during the postoperative follow-up. No cases of recurring instability occurred. Two cases had neuroma and one experienced irritation of the suture site. Six patients had residual limitation of combined lateral rotation and abduction movements, of a mean of 10 degrees compared with the healthy contralateral side. The most frequent incident was the leak of solutions to the soft tissues. Capsular retensioning, whether combined or not with other anatomical repair techniques, has proven to result in a highly satisfactory rate of glenohumeral stabilization in cases of anterior unidirectional instabilities. The arthroscopic approach offers the well-known advantages of causing less damage to the soft tissues, and a shorter time to starting rehabilitation therapy and exercises.

  12. Lateral human-structure interaction on footbridges

    DEFF Research Database (Denmark)

    Ingólfsson, Einar Thór; Georgakis, Christos; Ricciardelli, Francesco


    In recent years, several high-profile footbridges have suffered from unexpected excessive pedestrian-induced lateral vibrations. There is a commonly accepted view that the synchronisation of pedestrians to the lateral movement of a structure is necessary for the onset of a form of instability which....... The tests reveal that synchronisation is not a pre-condition for the development of large amplitude lateral vibrations on footbridges, as walking frequencies and phase angles remain largely unaffected by lateral motion at most frequencies and amplitudes. Instead, large amplitude vibrations are the result...

  13. Relative role of convective and diffusive mixing in the miscible Rayleigh-Taylor instability in porous media (United States)

    Gopalakrishnan, S. S.; Carballido-Landeira, J.; De Wit, A.; Knaepen, B.


    The relative role of convection and diffusion is characterized both numerically and experimentally for porous media flows due to a Rayleigh-Taylor instability of a horizontal interface between two miscible solutions in the gravity field. We show that, though globally convection dominates over diffusion during the nonlinear regime, diffusion can locally be as important as convection and even dominates over lateral convection far away from the fingertips. Our experimental and numerical computations of the temporal evolution of the mixing length, the width of the fingers, and their wavelength are in good agreement and show that the lateral evolution of fingers is governed by diffusion.

  14. 带线锚钉在11例慢性踝关节外侧不稳韧带重建中的应用%With wire anchors application in the ligament reconstruction of 11 pa-tients with chronic lateral ankle instability

    Institute of Scientific and Technical Information of China (English)

    王波; 武亚娟; 侯勇


    Objective To investigate the value of with wire anchors in the treatment of cable anchors with chronic lat-eral ankle instability. Methods Selected 11 patients with chronic lateral ankle instability from January 2009 to Decem-ber 2012,7 males and 4 females,average age were(24.8±6.5) years,all implemented with wire anchors surgery to anatomi-cal reconstruction lateral ligaments,follow-up of 3 to 12 months postoperative,used a modified American Orthopaedic Foot and Ankle Society(AOFAS) scale to evaluate ankle function. Results Modified AOFAS ankle score excellent in 6 cases,good in 3 cases, fine in 1 case, poor in 1 case,good rate was 81.82%.AOFAS ankle scores were higher than preoperative after 3 months (P<0.05 or P<0.01); postoperative talar tilt angle,talar shift distance,ankle medial joint space was less than before(P<0.01). Conclusion With wire anchors application in the anatomical reconstruction of lat-eral ankle ligaments,the ligaments can restore the stability of the ankle, joint function recovered well, worthy of pro-motion apply.%目的:探讨带线锚钉在慢性踝关节外侧不稳治疗中的应用价值。方法选取2009年1月~2013年12月收治的慢性踝关节外侧不稳定患者11例,男7例,女4例;平均年龄(24.8±6.5)岁;均实施带线锚钉手术解剖重建外侧韧带,术后随访3~12个月,采用改良美国足踝骨科协会(AOFAS)足踝评分评价踝关节功能。结果改良AOFAS足踝评分优6例,良3例,可1例,差1例,优良率为81.82%。术后3个月改良AOFAS足踝评分均高于术前(P<0.05或P<0.01);术后距骨倾斜角度、距骨移位距离、踝关节内侧间隙均小于术前(P<0.01)。结论带线锚钉解剖重建踝关节外侧韧带能恢复韧带稳定性,踝关节功能恢复良好,值得临床推广适用。

  15. Long-term sequel of posterolateral rotatory instability of the elbow: a case report

    Directory of Open Access Journals (Sweden)

    Cheng Chun-Ying


    Full Text Available Abstract The natural course of untreated posterior lateral rotatory instability of the elbow is unclear. A case of elbow arthrosis with progressing deformity and flexion contracture after an episode of elbow dislocation about 20 years ago presented the possibility the long term outcome of untreated posterior lateral rotatory instability of the elbow.

  16. Cavitation Instabilities in Inducers (United States)


    gas handling turbomachines . The fluctuation of the cavity length is plotted in Fig.8 under the surge mode oscillation vi . The major differences...Cavitation Instabilities of Turbomachines .” AIAA Journal of Propulsion and Power, Vol.17, No.3, 636-643. [5] Tsujimoto, Y., (2006), “Flow Instabilities in

  17. Instability in evolutionary games.

    Directory of Open Access Journals (Sweden)

    Zimo Yang

    Full Text Available BACKGROUND: Phenomena of instability are widely observed in many dissimilar systems, with punctuated equilibrium in biological evolution and economic crises being noticeable examples. Recent studies suggested that such instabilities, quantified by the abrupt changes of the composition of individuals, could result within the framework of a collection of individuals interacting through the prisoner's dilemma and incorporating three mechanisms: (i imitation and mutation, (ii preferred selection on successful individuals, and (iii networking effects. METHODOLOGY/PRINCIPAL FINDINGS: We study the importance of each mechanism using simplified models. The models are studied numerically and analytically via rate equations and mean-field approximation. It is shown that imitation and mutation alone can lead to the instability on the number of cooperators, and preferred selection modifies the instability in an asymmetric way. The co-evolution of network topology and game dynamics is not necessary to the occurrence of instability and the network topology is found to have almost no impact on instability if new links are added in a global manner. The results are valid in both the contexts of the snowdrift game and prisoner's dilemma. CONCLUSIONS/SIGNIFICANCE: The imitation and mutation mechanism, which gives a heterogeneous rate of change in the system's composition, is the dominating reason of the instability on the number of cooperators. The effects of payoffs and network topology are relatively insignificant. Our work refines the understanding on the driving forces of system instability.

  18. Treatment of hip instability. (United States)

    Robbins, G M; Masri, B A; Garbuz, D S; Greidanus, N; Duncan, C P


    Instability after total hip arthroplasty is a major source of patient morbidity, second only to aseptic loosening. Certain patient groups have been identified as having a greater risk of instability, including patients undergoing revision arthroplasty as early or late treatment for proximal femoral fractures.

  19. Fluctuations and Instability in Sedimentation

    KAUST Repository

    Guazzelli, Élisabeth


    This review concentrates on the fluctuations of the velocities of sedimenting spheres, and on the structural instability of a suspension of settling fibers. For many years, theoretical estimates and numerical simulations predicted the fluctuations of the velocities of spheres to increase with the size of the container, whereas experiments found no such variation. Two ideas have increased our understanding. First, the correlation length of the velocity fluctuations was found experimentally to be 20 interparticle separations. Second, in dilute suspensions, a vertical variation in the concentration due to the spreading of the front with the clear fluid can inhibit the velocity fluctuations. In a very dilute regime, a homogeneous suspension of fibers suffers a spontaneous instability in which fast descending fiber-rich columns are separated by rising fiber-sparse columns. In a semidilute regime, the settling is hindered, more so than for spheres. © 2011 by Annual Reviews. All rights reserved.

  20. Placing Marangoni instabilities under arrest

    CERN Document Server

    Bhamla, M Saad


    Soap bubbles occupy the rare position of delighting and fascinating both young children and scientific minds alike. Sir Isaac Newton, Joseph Plateau, Carlo Marangoni, and Pierre-Gilles de Gennes, not to mention countless others, have discovered remarkable results in optics, molecular forces and fluid dynamics from investigating this seemingly simple system. We present here a compilation of curiosity-driven experiments that systematically investigate the surface flows on a rising soap bubble. From childhood experience, we are familiar with the vibrant colors and mesmerizing display of chaotic flows on the surface of a soap bubble. These flows arise due to surface tension gradients, also known as Marangoni flows or instabilities. In Figure 1, we show the surprising effect of layering multiple instabilities on top of each other, highlighting that unexpected new phenomena are still waiting to be discovered, even in the simple soap bubble.

  1. Magnetorotational Explosive Instability in Keplerian Disks

    CERN Document Server

    Shtemler, Yuri; Mond, Michael


    In this paper it is shown that deferentially rotating disks that are in the presence of weak axial magnetic field are prone to a new nonlinear explosive instability. The latter occurs due to the near-resonance three-wave interactions of a magnetorotational instability with stable Alfven-Coriolis and magnetosonic modes. The dynamical equations that govern the temporal evolution of the amplitudes of the three interacting modes are derived. Numerical solutions of the dynamical equations indicate that small frequency mismatch gives rise to two types of behavior: 1. explosive instability which leads to infinite values of the three amplitudes within a finite time, and 2. bounded irregular oscillations of all three amplitudes. Asymptotic solutions of the dynamical equations are obtained for the explosive instability regimes and are shown to match the numerical solutions near the explosion time.

  2. Nonlinear helical MHD instability

    Energy Technology Data Exchange (ETDEWEB)

    Zueva, N.M.; Solov' ev, L.S.


    An examination is made of the boundary problem on the development of MHD instability in a toroidal plasma. Two types of local helical instability are noted - Alfven and thermal, and the corresponding criteria of instability are cited. An evaluation is made of the maximum attainable kinetic energy, limited by the degree to which the law of conservation is fulfilled. An examination is made of a precise solution to a kinematic problem on the helical evolution of a cylindrical magnetic configuration at a given velocity distribution in a plasma. A numerical computation of the development of MHD instability in a plasma cylinder by a computerized solution of MHD equations is made where the process's helical symmetry is conserved. The development of instability is of a resonance nature. The instability involves the entire cross section of the plasma and leads to an inside-out reversal of the magnetic surfaces when there is a maximum unstable equilibrium configuration in the nonlinear stage. The examined instability in the tore is apparently stabilized by a magnetic hole when certain limitations are placed on the distribution of flows in the plasma. 29 references, 8 figures.

  3. Large-scale instabilities in a non-rotating turbulent convection

    CERN Document Server

    Elperin, T; Kleeorin, N; Rogachevskii, I


    Formation of large-scale coherent structures in a turbulent convection via excitation of large-scale instability is studied. The redistribution of the turbulent heat flux due to non-uniform large-scale motions plays a crucial role in the formation of the coherent large-scale structures in the turbulent convection. The modification of the turbulent heat flux results in strong reduction of the critical Rayleigh number (based on the eddy viscosity and turbulent temperature diffusivity) required for the excitation of the large-scale instability. The mean-field equations which describe the large-scale instability, are solved numerically. We determine the key parameters that affect formation of the large-scale coherent structures in the turbulent convection. In particular, the degree of thermal anisotropy and the lateral background heat flux strongly modify the growth rates of the large-scale instability, the frequencies of the generated convective-shear waves and change the thresholds required for the excitation o...

  4. Instabilities in nuclei

    CERN Document Server

    Csernai, László P; Papp, G


    The evolution of dynamical perturbations is examined in nuclear multifragmentation in the frame of Vlasov equation. Both plane wave and bubble type of perturbations are investigated in the presence of surface (Yukawa) forces. An energy condition is given for the allowed type of instabilities and the time scale of the exponential growth of the instabilities is calculated. The results are compared to the mechanical spinodal region predictions. PACS: 25.70 Mn

  5. Prediction of Algebraic Instabilities (United States)

    Zaretzky, Paula; King, Kristina; Hill, Nicole; Keithley, Kimberlee; Barlow, Nathaniel; Weinstein, Steven; Cromer, Michael


    A widely unexplored type of hydrodynamic instability is examined - large-time algebraic growth. Such growth occurs on the threshold of (exponentially) neutral stability. A new methodology is provided for predicting the algebraic growth rate of an initial disturbance, when applied to the governing differential equation (or dispersion relation) describing wave propagation in dispersive media. Several types of algebraic instabilities are explored in the context of both linear and nonlinear waves.

  6. The Role of the Magnetorotational Instability in Massive Stars

    CERN Document Server

    Wheeler, J Craig; Chatzopoulos, Emmanouil


    The magnetorotational instability (MRI) is key physics in accretion disks and is widely considered to play some role in massive-star core collapse. Models of rotating massive stars naturally develop very strong shear at composition boundaries, a necessary condition for MRI instability, and the MRI is subject to triply-diffusive destabilizing effects in radiative regions. We have used the MESA stellar evolution code to compute magnetic effects due to the Spruit-Taylor mechanism and the MRI, separately and together, in a sample of massive star models. We find that the MRI can be active in the later stages of massive star evolution, leading to mixing effects that are not captured in models that neglect the MRI. The MRI and related magneto-rotational effects can move models of given ZAMS mass across "boundaries" from degenerate CO cores to degenerate O/Ne/Mg cores and from degenerate O/Ne/Mg cores to iron cores, thus affecting the final evolution and the physics of core collapse. The MRI acting alone can slow the...

  7. Imaging of patellofemoral instability; Bildgebung der patellofemoralen Instabilitaet

    Energy Technology Data Exchange (ETDEWEB)

    Waldt, S.; Rummeny, E.J. [Klinikum rechts der Isar, Technische Universitaet Muenchen, Institut fuer diagnostische und interventionelle Radiologie, Muenchen (Germany)


    Patellofemoral instability remains a diagnostic and therapeutic challenge due to its multifactorial genesis. The purpose of imaging is to systematically analyze predisposing factors, such as trochlear dysplasia, patella alta, tibial tuberosity-trochlear groove (TT-TG) distance, rotational deformities of the lower limb and patellar tilt. In order to evaluate anatomical abnormalities with a sufficient diagnostic accuracy, standardized measurement methods and implementation of various imaging modalities are necessary. Diagnosis of acute and often overlooked lateral patellar dislocation can be established with magnetic resonance imaging (MRI) because of its characteristic patterns of injury. Damage to the medial patellofemoral ligament (MPFL) has a significance just as high as the predisposing risk factors in relation to the cause of chronic instability. (orig.) [German] Die patellofemorale Instabilitaet stellt aufgrund ihrer multifaktoriellen Genese eine diagnostische und therapeutische Herausforderung dar. Aufgabe der Bildgebung ist es, anlagebedingte Risikofaktoren wie Trochleadysplasie, Patellahochstand, Torsionsfehlstellungen der unteren Extremitaet, TTTG-Abstand und Patellatilt systematisch zu analysieren. Um die aetiologischen Faktoren mit einer ausreichenden diagnostischen Genauigkeit zu bewerten, sind standardisierte und umfangreich evaluierte Messverfahren sowie der gezielte Einsatz verschiedener bildgebender Modalitaeten erforderlich. Die Diagnose einer traumatischen, oftmals klinisch inapparenten Patellaluxation kann anhand der charakteristischen Befundkonstellation in der MRT gestellt werden. Der Schaedigung des medialen patellofemoralen Ligaments (Elogantion/Ruptur) im Rahmen einer akuten Luxation wird, aehnlich wie den anlagebedingten Risikofaktoren, eine grosse Bedeutung im Hinblick auf die Entstehung einer chronischen Instabilitaet beigemessen. (orig.)

  8. Systematics of shoulder instability; Systematik der Schulterinstabilitaet

    Energy Technology Data Exchange (ETDEWEB)

    Kreitner, K.F.; Maehringer-Kunz, A. [Johannes-Gutenberg-Universitaet Mainz, Klinik und Poliklinik fuer Diagnostische und Interventionelle Radiologie, Mainz (Germany)


    Shoulder instability is defined as a symptomatic abnormal motion of the humeral head relative to the glenoid during active shoulder motion. Glenohumeral instabilities are classified according to the causative factors as the pathogenesis of instability plays an important role with respect to treatment options. Instabilities are classified into traumatic and atraumatic instabilities as part of a multidirectional instability syndrome and into microtraumatic instabilities. For diagnostics plain radiographs (''trauma series'') are performed to document shoulder dislocation and its successful repositioning. Direct magnetic resonance (MR) arthrography is the most important imaging modality for delineation of the different injury patterns of the labral-ligamentous complex and bony structures. Monocontrast computed tomography (CT) arthrography with the use of multidetector CT scanners represents an alternative imaging modality; however, MR imaging should be preferred in the work-up of shoulder instabilities due to the mostly younger age of patients. (orig.) [German] Unter einer Schulterinstabilitaet versteht man jede zu Beschwerden fuehrende Translation des Humeruskopfs in Relation zur Gelenkpfanne waehrend einer aktiven Bewegung der Schulter. Glenohumerale Instabilitaeten werden heute nach ihrer Aetiologie eingeteilt, da bei der Wahl der Therapie der Entstehungsmechanismus der Instabilitaet eine wichtige Rolle spielt. Danach unterscheidet man primaer traumatisch von atraumatisch entstandenen Instabilitaeten sowie Mikroinstabilitaeten. Bei der Diagnostik dienen konventionelle Roentgenuebersichtsaufnahmen nur noch zur Dokumentation einer Luxation und zur Beurteilung der Reposition. Die durch eine Instabilitaet hervorgerufenen Verletzungsfolgen am labroligamentaeren Komplex und den knoechernen Strukturen werden heute bevorzugt mit der direkten MR-Arthrographie dargestellt. Hierbei koennen unterschiedliche Verletzungsmuster dargestellt werden. Nach

  9. Propagating Instabilities in Solids (United States)

    Kyriakides, Stelios


    Instability is one of the factors which limit the extent to which solids can be loaded or deformed and plays a pivotal role in the design of many structures. Such instabilities often result in localized deformation which precipitates catastrophic failure. Some materials have the capacity to recover their stiffness following a certain amount of localized deformation. This local recovery in stiffness arrests further local deformation and spreading of the instability to neighboring material becomes preferred. Under displacement controlled loading the propagation of the transition fronts can be achieved in a steady-state manner at a constant stress level known as the propagation stress. The stresses in the transition fronts joining the highly deformed zone to the intact material overcome the instability nucleation stresses and, as a result, the propagation stress is usually much lower than the stress required to nucleate the instability. The classical example of this class of material instabilities is L/"uders bands which tend to affect mild steels and other metals. Recent work has demonstrated that propagating instabilities occur in several other materials. Experimental and analytical results from four examples will be used to illustrate this point: First the evolution of L=FCders bands in mild steel strips will be revisited. The second example involves the evolution of stress induced phase transformations (austenite to martensite phases and the reverse) in a shape memory alloy under displacement controlled stretching. The third example is the crushing behavior of cellular materials such as honeycombs and foams made from metals and polymers. The fourth example involves the axial broadening/propagation of kink bands in aligned fiber/matrix composites under compression. The microstructure and, as a result, the micromechanisms governing the onset, localization, local arrest and propagation of instabilities in each of the four materials are vastly different. Despite this

  10. Instability of enclosed horizons (United States)

    Kay, Bernard S.


    We point out that there are solutions to the scalar wave equation on dimensional Minkowski space with finite energy tails which, if they reflect off a uniformly accelerated mirror due to (say) Dirichlet boundary conditions on it, develop an infinite stress-energy tensor on the mirror's Rindler horizon. We also show that, in the presence of an image mirror in the opposite Rindler wedge, suitable compactly supported arbitrarily small initial data on a suitable initial surface will develop an arbitrarily large stress-energy scalar near where the two horizons cross. Also, while there is a regular Hartle-Hawking-Israel-like state for the quantum theory between these two mirrors, there are coherent states built on it for which there are similar singularities in the expectation value of the renormalized stress-energy tensor. We conjecture that in other situations with analogous enclosed horizons such as a (maximally extended) Schwarzschild black hole in equilibrium in a (stationary spherical) box or the (maximally extended) Schwarzschild-AdS spacetime, there will be similar stress-energy singularities and almost-singularities—leading to instability of the horizons when gravity is switched on and matter and gravity perturbations are allowed for. All this suggests it is incorrect to picture a black hole in equilibrium in a box or a Schwarzschild-AdS black hole as extending beyond the past and future horizons of a single Schwarzschild (/Schwarzschild-AdS) wedge. It would thus provide new evidence for 't Hooft's brick wall model while seeming to invalidate the picture in Maldacena's ` Eternal black holes in AdS'. It would thereby also support the validity of the author's matter-gravity entanglement hypothesis and of the paper ` Brick walls and AdS/CFT' by the author and Ortíz.

  11. Plasma Instabilities and Transport in the MPD Thruster (United States)


    heating with increasing beta may be partly due to the fact that, at low beta, the instability has its dominant modes oriented at small angles to the...cross-field stream- ing instability. Physics of Fluids, 26(5):1259-1267, 1983. [25] S.T. Tsai, M. Tanaka, J.D. Gaffey Jr., E.H. Da Jornada , and C.S

  12. Baroclinic instability in the two-layer model. Interpretations

    Energy Technology Data Exchange (ETDEWEB)

    Egger, Joseph [Meteorological Inst., Univ. of Munich (Germany)


    Two new interpretations of the wellknown instability criterion of the two-layer model of baroclinic instability are given whereby also a slight generalization of this model is introduced by admitting an interface on top with a reduced gravity g. It is found that instability sets in when the horizontal potential temperature advection by the barotropic mode becomes more important than the vertical temperature advection due to this mode. The second interpretation is based on potential vorticity (PV) thinking. Instability implies a dominance of the vertical PV coupling coefficient compared to horizontal mean state PV advection generated at the same level. The interface damps with decreasing g. (orig.)

  13. Study on time-history characteristics of air blast wave due to great extent of roof instability%大面积顶板失稳诱发空气冲击波灾害时程特性研究

    Institute of Scientific and Technical Information of China (English)

    刘畅; 覃敏; 彭云


    rock block has a little increase and the whole catastrophic process continues for 2.89s.The wind speed reaches their extreme points as 508.1m/s after 2.1s, and the shock could reach 370m around the site of the incident;(3) because of minor re-sistance at the primary step of falling , the speed of hurricane increases drastically .At intermediate stage , the wind speed climbs slowly and gradually arrives the peak .Due to tremendous resistance in the terminal stage , the speed of hurricane decreases sharply and airflow becomes flat in the lane .( 4 ) an implementation of filling must be put into practice as soon as possible , some measures such as grooming , plugging , setting buffer layer , ground pressure monitoring and so on , should be taken to reduce the ratio of accident and harm of air blast wave .

  14. Morphological instabilities of stratified epithelia: a mechanical instability in tumour formation

    CERN Document Server

    Risler, Thomas


    Interfaces between stratified epithelia and their supporting stromas commonly exhibit irregular shapes. Undulations are particularly pronounced in dysplastic tissues and typically evolve into long, finger-like protrusions in carcinomas. In a previous work (Basan et al., Phys. Rev. Lett. 106, 158101 (2011)), we demonstrated that an instability arising from viscous shear stresses caused by the constant flow due to cell turnover in the epithelium could drive this phenomenon. While interfacial tension between the two tissues as well as mechanical resistance of the stroma tend to maintain a flat interface, an instability occurs for sufficiently large viscosity, cell-division rate and thickness of the dividing region in the epithelium. Here, extensions of this work are presented, where cell division in the epithelium is coupled to the local concentration of nutrients or growth factors diffusing from the stroma. This enhances the instability by a mechanism similar to that of the Mullins-Sekerka instability in single...

  15. Neutrino beam plasma instability

    Indian Academy of Sciences (India)

    Vishnu M Bannur


    We derive relativistic fluid set of equations for neutrinos and electrons from relativistic Vlasov equations with Fermi weak interaction force. Using these fluid equations, we obtain a dispersion relation describing neutrino beam plasma instability, which is little different from normal dispersion relation of streaming instability. It contains new, nonelectromagnetic, neutrino-plasma (or electroweak) stable and unstable modes also. The growth of the instability is weak for the highly relativistic neutrino flux, but becomes stronger for weakly relativistic neutrino flux in the case of parameters appropriate to the early universe and supernova explosions. However, this mode is dominant only for the beam velocity greater than 0.25 and in the other limit electroweak unstable mode takes over.

  16. Causes of genome instability

    DEFF Research Database (Denmark)

    Langie, Sabine A S; Koppen, Gudrun; Desaulniers, Daniel


    , genome instability can be defined as an enhanced tendency for the genome to acquire mutations; ranging from changes to the nucleotide sequence to chromosomal gain, rearrangements or loss. This review raises the hypothesis that in addition to known human carcinogens, exposure to low dose of other...... scientists aware of the increasing need to unravel the underlying mechanisms via which chemicals at low doses can induce genome instability and thus promote carcinogenesis.......Genome instability is a prerequisite for the development of cancer. It occurs when genome maintenance systems fail to safeguard the genome's integrity, whether as a consequence of inherited defects or induced via exposure to environmental agents (chemicals, biological agents and radiation). Thus...

  17. Dynamic Radiographic Analysis of Sympathetic Cervical Spondylosis Instability

    Institute of Scientific and Technical Information of China (English)

    Jun Qian; Ye Tian; Gui-xing Qiu; Jian-hua Hu


    Objective To investigate the correlation between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms as well as the difference of cervical spondylotic subaxial instability between male and female patients. Methods We analyzed retrospectively 318 surgical cases of cervical spondylosis treated at Department of Orthopedic Surgery of Peking Union Medical College Hospital between July 2003 and December 2007. All cases were divided into group A without sympathetic symptoms (n=284) and group B with sympathetic symptoms (n=34). Angular and horizontal translation values between two adjacent vertebral bodies from C2 to C7 were measured separately on hyperflexion and hyperextension lateral cervical spine radiographs. Fisher's exact test was used to evaluate the correlation between subaxial cervical instability and sympathetic symptoms. Intragroup correlation between patient gender and subaxial cervical instability was also evaluated. Results Subaxial instability incidences in groups A and B were 21.8% (62/284) and 55.9% (19/34), respectively. Statistical analysis indicated a definite correlation between subaxial cervical instability and sympathetic symptoms (P=0.000). Among patients without sympathetic symptoms, subaxial instability incidences were 21.4% (37/173) in males and 22.5% (25/111) in females, respectively (P=0.883). While among patients with sympathetic symptoms, subaxial instability incidences were 27.3% (3/11) in males and 69.6% (16/23) in females, respectively, indicating significant difference (P=0.030). Subaxial instability was most commonly seen at C4-C5 intervertebral space in sympathetic cervical spondylosis patients. Conclusions High correlation exists between subaxial cervical spine instability and cervical spondylotic sympathetic symptoms, especially in female patients. Hyperextension and hyperflexion radiographs of cervical spine are important to assess sympathetic cervical spondylotic subaxial instability.

  18. Biomechanical study of patellofemoral joint instability (United States)

    Senavongse, Wongwit


    Patellofemoral joint instability is a complex clinical problem. It may be a consequence of pre-existing anatomical abnormality or trauma. The objectives of this study were to use experimental mechanics to measure patellar stability and to quantify the effects of pathological abnormalities on patellar stability in vitro. Eight fresh-frozen cadaver knees were studies. The patellar stability was measured using an Instron material testing machine. A total load of 175N was applied to the quadriceps muscles. Patellar force-displacement was tested at different knee flexion angles as the patella was cyclically displaced 10mm laterally and medially. Three pathological abnormalities were applied; VMO malfunction, flat lateral trochlea, and medial retinacular structure rupturing. For the first time, this study has shown comparative and quantitative influence of pathological abnormalities on patellar stability. It was found that a flat lateral trochlea has greater effect than the medial retinacular rupturing whereas the medial retinacular rupturing has greater effect than VMO malfunction on patellar lateral stability. These results are important for future investigations on the treatment of patellofemoral instability.

  19. A fast beam-ion instability

    Energy Technology Data Exchange (ETDEWEB)

    Stupakov, G.V. [Stanford Linear Accelerator Center, Menlo Park, CA (United States)


    The ionization of residual gas by an electron beam in an accelerator generates ions that can resonantly couple to the beam through a wave propagating in the beam-ion system. Results of the study of a beam-ion instability are presented for a multi-bunch train taking into account the decoherence of ion oscillations due to the ion frequency spread and spatial variation of the ion frequency. It is shown that the combination of both effects can substantially reduce the growth rate of the instability. (author)

  20. Polyhedral (in-)stability of protein crystals (United States)

    Nanev, Christo N.; Penkova, Anita N.


    The polyhedral (in-)stability of monoclinic hen-egg white lysozyme (HEWL) crystals, grown by means of PEG-6000, and that of orthorhombic trypsin crystals has been investigated experimentally. On the basis of a quantitative theoretical analysis, it is compared with the polyhedral (in-)stability of tetragonal HEWL and cubic ferritin crystals. The unambiguous conclusion is that the phenomenon is due to the diffusive supply of matter. This conclusion is also supported by the fact that the phenomenon has common features for both proteins and small molecular crystals.

  1. Mixing through shear instabilities

    CERN Document Server

    Brüggen, M


    In this paper we present the results of numerical simulations of the Kelvin-Helmholtz instability in a stratified shear layer. This shear instability is believed to be responsible for extra mixing in differentially rotating stellar interiors and is the prime candidate to explain the abundance anomalies observed in many rotating stars. All mixing prescriptions currently in use are based on phenomenological and heuristic estimates whose validity is often unclear. Using three-dimensional numerical simulations, we study the mixing efficiency as a function of the Richardson number and compare our results with some semi-analytical formalisms of mixing.

  2. Recurrent posterior shoulder instability after rifle shooting. (United States)

    Cho, Jae-Ho; Chung, Nam-Su; Song, Hyung-Keun; Lee, Doo-Hyung


    Rifle shooting produces a sudden counterforce against the body thorough the anterior shoulder, which may produce a traumatic injury in soldiers. Posterior instability of the shoulder can occur in soldiers who practice rifle shooting. To the authors' knowledge, few reports have examined shooting-related injuries in soldiers. This article describes the case of a 27-year-old male soldier who presented with left shoulder pain and instability after rifle training. He developed symptoms, and presented radiographic findings consistent with a posterior Bankart lesion. Intraoperatively, while in the lateral decubitus position, a posterior portal was created 3 cm inferior and 2 cm lateral to the posterolateral corner of acromion for making a proper angle for inserting anchors. A reverse bony Bankart lesion and adjacent cartilage breakdown at the glenoid rim were noted. An arthroscopic capsulolabral repair was performed with 3-mm bioabsorbable anchors to the glenoid rim. No gross reverse Hill-Sachs lesion or hyaline cartilage lesion was noted. Postoperatively, the arm was supported in a sling with an abduction pillow for 5 weeks. Codman's exercises, scapular protraction exercises, and elbow and wrist exercises were started. Physical therapy focused on reestablishing glenohumeral range of motion and rotator cuff and periscapular muscle strength. Six months postoperatively, the patient had normal scapular kinesis and reported no shoulder pain or symptoms of instability associated with a reverse bony Bankart lesion. Copyright 2012, SLACK Incorporated.

  3. Compressor instability with integral methods

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Y.K. Eddie [Nanyang Technological Univ., Singapore (Singapore). School of Mechanical and Aerospace Engineering; Liu, Ningyu [Singapore National Univ. (Singapore). Dept. of Mechanical Engineering


    ''Compressor Instability with Integral Methods'' is a book, to bring together the quick integral approaches and advances in the field for the prediction of stall and surge problem in compressor. This book is useful for people involved in the flow analysis, design and testing of rotating machinery. For students, it can be used as a specialized topic of senior undergraduate or graduate study. The book can also be served as a self-study material to those who keen to acquire this knowledge. In brief, this book focuses on the numerical/computational analysis for the effect of distorted inlet flow propagation on the rotating stall and surge in axial compressors. It gains insight into the basic phenomena controlling these flow instabilities, and reveals the influence of inlet parameters on rotating stall and surge. The book starts from the confirmation and application of Kim et al's integral method and then follows by a development to this method through the proposing and applying a critical distortion line. This line is applied successfully on the stall prediction of in-flight compressor due to flaming of refueling leakage near inlet, a typical real and interesting example of compressor stall and surge operation. Further, after a parametric study on the integral method and the distorted flow field of compressor using Taguchi method, a novel integral method is formulated using more appropriate and practical airfoil characteristics, with a less assumptions needed for derivation. Finally, as an extended work, the famous Greitzer's instability flow model, the well-known B-parameter model applied for analyzing the stall and surge characteristics, is studied parametrically using Taguchi method. (orig.)

  4. Ion sound instability driven by ion beam

    CERN Document Server

    Koshkarov, O; Kaganovich, I D; Ilgisonis, V I


    In many natural and laboratory conditions, plasmas are often in the non-equilibrium state due to presence of stationary flows, when one particle species (or a special group, such as group of high energy particles, i.e. beam) is mowing with respect to the other plasma components. Such situations are common for a number of different plasma application such as diagnostics with emissive plasma probes, plasma electronics devices and electric propulsion devices. The presence of plasma flows often lead to the instabilities in such systems and subsequent development of large amplitude perturbations. The goal of this work is to develop physical insights and numerical tools for studies of stability of the excitation of the ion sound waves by the ion beam in the configuration similar to the plasma Pierce diode. This systems, in some limiting cases, reduce to mathematically similar equations originally proposed for Pierce instability. The finite length effect are crucial for this instability which generally belong to the...

  5. Rational Instability in the Natural Coalition Forming

    CERN Document Server

    Vinogradova, Galina


    We are investigating a paradigm of instability in coalition forming among countries, which indeed is intrinsic to any collection of individual groups or other social aggregations. Coalitions among countries are formed by the respective attraction or repulsion caused by the historical bond propensities between the countries, which produced an intricate circuit of bilateral bonds. Contradictory associations into coalitions occur due to the independent evolution of the bonds. Those coalitions tend to be unstable and break down frequently. The model extends some features of the physical theory of Spin Glasses. Within the frame of this model, the instability is viewed as a consequence of decentralized maximization processes searching for the best coalition allocations. In contrast to the existing literature, a rational instability is found to result from forecast rationality of countries. Using a general theoretical framework allowing to analyze the countries' decision making in coalition forming, we feature a sys...

  6. 3D Relativistic Magnetohydrodynamic Simulations of Current-Driven Instability. 1; Instability of a Static Column (United States)

    Mizuno, Yosuke; Lyubarsky, Yuri; ishikawa, Ken-Ichi; Hardee, Philip E.


    We have investigated the development of current-driven (CD) kink instability through three-dimensional relativistic MHD simulations. A static force-free equilibrium helical magnetic configuration is considered in order to study the influence of the initial configuration on the linear and nonlinear evolution of the instability. We found that the initial configuration is strongly distorted but not disrupted by the kink instability. The instability develops as predicted by linear theory. In the non-linear regime the kink amplitude continues to increase up to the terminal simulation time, albeit at different rates, for all but one simulation. The growth rate and nonlinear evolution of the CD kink instability depends moderately on the density profile and strongly on the magnetic pitch profile. The growth rate of the kink mode is reduced in the linear regime by an increase in the magnetic pitch with radius and the non-linear regime is reached at a later time than for constant helical pitch. On the other hand, the growth rate of the kink mode is increased in the linear regime by a decrease in the magnetic pitch with radius and reaches the non-linear regime sooner than the case with constant magnetic pitch. Kink amplitude growth in the non-linear regime for decreasing magnetic pitch leads to a slender helically twisted column wrapped by magnetic field. On the other hand, kink amplitude growth in the non-linear regime nearly ceases for increasing magnetic pitch.

  7. Lateral Elbow Tendinopathy (United States)

    Bhabra, Gev; Wang, Allan; Ebert, Jay R.; Edwards, Peter; Zheng, Monica; Zheng, Ming H.


    Lateral elbow tendinopathy, commonly known as tennis elbow, is a condition that can cause significant functional impairment in working-age patients. The term tendinopathy is used to describe chronic overuse tendon disorders encompassing a group of pathologies, a spectrum of disease. This review details the pathophysiology of tendinopathy and tendon healing as an introduction for a system grading the severity of tendinopathy, with each of the 4 grades displaying distinct histopathological features. Currently, there are a large number of nonoperative treatments available for lateral elbow tendinopathy, with little guidance as to when and how to use them. In fact, an appraisal of the clinical trials, systematic reviews, and meta-analyses studying these treatment modalities reveals that no single treatment reliably achieves outstanding results. This may be due in part to the majority of clinical studies to date including all patients with chronic tendinopathy rather than attempting to categorize patients according to the severity of disease. We relate the pathophysiology of the different grades of tendinopathy to the basic science principles that underpin the mechanisms of action of the nonoperative treatments available to propose a treatment algorithm guiding the management of lateral elbow tendinopathy depending on severity. We believe that this system will be useful both in clinical practice and for the future investigation of the efficacy of treatments. PMID:27833925

  8. Dynamical instabilities in disc-planet interactions

    CERN Document Server

    Lin, Min-Kai


    Protoplanetary discs may become dynamically unstable due to structure induced by an embedded giant planet. In this thesis, I discuss the stability of such systems and explore the consequence of instability on planetary migration. I begin with non-self-gravitating, low viscosity discs and show that giant planets induce shocks inside its co-orbital region, leading to a profile unstable to vortex formation around a potential vorticity minimum. This instability is commonly known as the vortex or Rossby wave instability. Vortex-planet interaction lead to episodic phases of migration, which can be understood in the framework of type III migration. I then examine the effect of disc self-gravity on gap stability. The linear theory of the Rossby wave instability is extended to include disc gravity, which shows that self-gravity is effective at stabilising the vortex instability at small azimuthal wavenumber. This is consistent with the observation that more vortices develop with increasing disc mass in hydrodynamic si...

  9. Coherent Instabilities of ILC Damping Ring

    Energy Technology Data Exchange (ETDEWEB)

    Heifets, S.; Stupakov, G.; Bane, K.; /SLAC


    The paper presents the first attempt to estimates the ILC damping ring impedance and compare thresholds of the classical instabilities for several designs initially proposed for the DR. The work was carried out in the spring of 2006. Since then the choice of the DR is narrowed. Nevertheless, the analysis described may be useful for the next iterations of the beam stability. Overall, the conventional instabilities will have little impact on the ring performance provided the careful design of the ring minimizes the impedance below acceptable level indicated above. The only exception is the transverse CB instability. The longitudinal CB is less demanding. However, even the transverse CB instability would have threshold current above nominal provided the aperture in the wigglers is increased from 8 mm to 16 mm. The microwave instability needs more studies. Nevertheless, we should remember that the ILC DR is different from existing high-current machines at least in two respects: absence of the beam-beam tune spread stabilizing beams in colliders, and unusual strict requirements for low emittance. That may cause new problems such as bunch emittance dilution due to high-frequency wakes (BPMs, grooves), etc. Even if such a possibility exists, it probably universal for all machines and ought be addressed in the design of vacuum components rather than have effect on the choice of the machine design.

  10. Pressure-driven instabilities in astrophysical jets

    CERN Document Server

    Longaretti, Pierre-Yves


    Astrophysical jets are widely believed to be self-collimated by the hoop-stress due to the azimuthal component of their magnetic field. However this implies that the magnetic field is largely dominated by its azimuthal component in the outer jet region. In the fusion context, it is well-known that such configurations are highly unstable in static columns, leading to plasma disruption. It has long been pointed out that a similar outcome may follow for MHD jets, and the reasons preventing disruption are still not elucidated, although some progress has been accomplished in the recent years. In these notes, I review the present status of this open problem for pressure-driven instabilities, one of the two major sources of ideal MHD instability in static columns (the other one being current-driven instabilities). I first discuss in a heuristic way the origin of these instabilities. Magnetic resonances and magnetic shear are introduced, and their role in pressure-driven instabilities discussed in relation to Suydam'...

  11. Fiber amplifiers under thermal loads leading to transverse mode instability

    DEFF Research Database (Denmark)

    Johansen, Mette Marie; Hansen, Kristian Rymann; Alkeskjold, Thomas Tanggaard;


    Transverse mode instability (TMI) in rare-earth doped fiber amplifiers operating above an average power threshold is caused by intermodal stimulated thermal Rayleigh scattering due to quantum defect heating. We investigate thermally induced longitudinal waveguide perturbations causing power trans...

  12. Primary instabilities in convective cells due to nonuniform heating (United States)

    Mancho, A. M.; Herrero, H.; Burguete, J.


    We study a convection problem in a container with a surface open to the air and heated by a long wire placed at the bottom. Coupled buoyancy and thermocapillarity effects are taken into account. A basic convective state appears as soon as a temperature gradient with horizontal component different from zero is applied. It consists of two big rolls that fill the convective cell and are parallel to the heater. A numerical solution allows us to determine this basic state. A linear stability analysis on this solution is carried out. For different values of the applied temperature gradient the basic rolls undergo a stationary bifurcation. The thresholds depend on the fluid properties, on the geometry of the heater, and on the heat exchange on the free surface. This confirms the results obtained in recent experiments.

  13. Identification of active release planes using ground-based differential InSAR at the Randa rock slope instability, Switzerland

    Directory of Open Access Journals (Sweden)

    V. Gischig


    Full Text Available Five ground-based differential interferometric synthetic aperture radar (GB-DInSAR surveys were conducted between 2005 and 2007 at the rock slope instability at Randa, Switzerland. Resultant displacement maps revealed, for the first time, the presence of an active basal rupture zone and a lateral release surface daylighting on the exposed 1991 failure scarp. Structures correlated with the boundaries of interferometric displacement domains were confirmed using a helicopter-based LiDAR DTM and oblique aerial photography. Former investigations at the site failed to conclusively detect these active release surfaces essential for kinematic and hazard analysis of the instability, although their existence had been hypothesized. The determination of the basal and lateral release planes also allowed a more accurate estimate of the currently unstable volume of 5.7±1.5 million m3. The displacement patterns reveal that two different kinematic behaviors dominate the instability, i.e. toppling above 2200 m and translational failure below. In the toppling part of the instability the areas with the highest GB-DInSAR displacements correspond to areas of enhanced micro-seismic activity. The observation of only few strongly active discontinuities daylighting on the 1991 failure surface points to a rather uniform movement in the lower portion of the instability, while most of the slip occurs along the basal rupture plane. Comparison of GB-DInSAR displacements with mapped discontinuities revealed correlations between displacement patterns and active structures, although spatial offsets occur as a result of the effective resolution of GB-DInSAR. Similarly, comparisons with measurements from total station surveys generally showed good agreement. Discrepancies arose in several cases due to local movement of blocks, the size of which could not be resolved using GB-DInSAR.

  14. Option price and market instability (United States)

    Baaquie, Belal E.; Yu, Miao


    An option pricing formula, for which the price of an option depends on both the value of the underlying security as well as the velocity of the security, has been proposed in Baaquie and Yang (2014). The FX (foreign exchange) options price was empirically studied in Baaquie et al., (2014), and it was found that the model in general provides an excellent fit for all strike prices with a fixed model parameters-unlike the Black-Scholes option price Hull and White (1987) that requires the empirically determined implied volatility surface to fit the option data. The option price proposed in Baaquie and Cao Yang (2014) did not fit the data during the crisis of 2007-2008. We make a hypothesis that the failure of the option price to fit data is an indication of the market's large deviation from its near equilibrium behavior due to the market's instability. Furthermore, our indicator of market's instability is shown to be more accurate than the option's observed volatility. The market prices of the FX option for various currencies are studied in the light of our hypothesis.

  15. Minimally invasive lateral transpsoas approach for spinal discitis and osteomyelitis. (United States)

    Patel, Neal B; Dodd, Zachary H; Voorhies, Jason; Horn, Eric M


    We present a series of patients with discitis and osteomyelitis who were surgically treated via a minimally invasive lateral transpsoas approach to the lumbar spine. Surgical treatment for spinal discitis and osteomyelitis presents challenges because of comorbidities that are common in patients undergoing this procedure. A retrospective review found six patients who met strict operative criteria including instability, intractable pain, neurological deficit, and disease progression. All patients were non-ambulatory before surgery because of intractable back pain. The patients underwent standard lateral minimally invasive surgery using either the extreme lateral interbody fusion (NuVasive, San Diego, CA, USA) or direct lateral interbody fusion (Medtronic Sofamor Danek, Memphis, TN, USA) system. The patients underwent debridement with a discectomy and partial or complete corpectomy, with polyetheretherketone or titanium cage placement. Two patients had additional posterior fixation with percutaneous pedicle screws, and none had immediate perioperative complications. The postoperative CT scans demonstrated satisfactory debridement and hardware placement. All patients experienced significant pain improvement and could ambulate within a few days of surgery. So far, the 1 year follow-up data have demonstrated stable hardware with solid fusion and continued pain improvements. One patient demonstrated hardware failure secondary to refractory infection, 2 months postoperatively, and required additional posterior decompression and debridement with pedicle screw fixation. The lateral transpsoas approach permits debridement and fixation coupled with percutaneous pedicle screw fixation to further stabilize the spine in a minimally invasive fashion. Due to the significant comorbidities in this patient population, a minimally invasive approach is a suitable surgical technique. A close follow-up period is necessary to detect early hardware failure which may necessitate more

  16. Shock instability in dissipative gases


    Radulescu, Matei I.; Sirmas, Nick


    Previous experiments have revealed that shock waves in thermally relaxing gases, such as ionizing, dissociating and vibrationally excited gases, can become unstable. To date, the mechanism controlling this instability has not been resolved. Previous accounts of the D'yakov-Kontorovich instability, and Bethe-Zel'dovich-Thompson behaviour could not predict the experimentally observed instability. To address the mechanism controlling the instability, we study the propagation of shock waves in a ...

  17. Erratum: SDO-AIA Observation of Kelvin-helmholtz Instability in the Solar Corona (United States)

    Ofman, Leon; Thompson, Barbara J.


    The first SDOAIA observation of the KelvinHelmholtz instability in the solar corona in the 2010 April 8 event was reported by Ofman Thompson (2010, 2011). Foullon et al. (2011), which was published prior to Ofman Thompson (2011), claimed the detection of the KelvinHelmholtz instability in a later event (2010 November 3), and should have been cited in Ofman Thompson (2011).

  18. Mechanisms of cadmium induced genomic instability

    Energy Technology Data Exchange (ETDEWEB)

    Filipic, Metka, E-mail: [National Institute of Biology, Department for Genetic Toxicology and Cancer Biology, Ljubljana (Slovenia)


    Cadmium is an ubiquitous environmental contaminant that represents hazard to humans and wildlife. It is found in the air, soil and water and, due to its extremely long half-life, accumulates in plants and animals. The main source of cadmium exposure for non-smoking human population is food. Cadmium is primarily toxic to the kidney, but has been also classified as carcinogenic to humans by several regulatory agencies. Current evidence suggests that exposure to cadmium induces genomic instability through complex and multifactorial mechanisms. Cadmium dose not induce direct DNA damage, however it induces increase in reactive oxygen species (ROS) formation, which in turn induce DNA damage and can also interfere with cell signalling. More important seems to be cadmium interaction with DNA repair mechanisms, cell cycle checkpoints and apoptosis as well as with epigenetic mechanisms of gene expression control. Cadmium mediated inhibition of DNA repair mechanisms and apoptosis leads to accumulation of cells with unrepaired DNA damage, which in turn increases the mutation rate and thus genomic instability. This increases the probability of developing not only cancer but also other diseases associated with genomic instability. In the in vitro experiments cadmium induced effects leading to genomic instability have been observed at low concentrations that were comparable to those observed in target organs and tissues of humans that were non-occupationally exposed to cadmium. Therefore, further studies aiming to clarify the relevance of these observations for human health risks due to cadmium exposure are needed.

  19. Nonlinear evolution of three-dimensional instabilities of thin and thick electron scale current sheets: Plasmoid formation and current filamentation

    Energy Technology Data Exchange (ETDEWEB)

    Jain, Neeraj; Büchner, Jörg [Max Planck/Princeton Center for Plasma Physics, Göttingen (Germany); Max Planck Institute for Solar System Research, Justus-Von-Liebig-Weg-3, Göttingen (Germany)


    Nonlinear evolution of three dimensional electron shear flow instabilities of an electron current sheet (ECS) is studied using electron-magnetohydrodynamic simulations. The dependence of the evolution on current sheet thickness is examined. For thin current sheets (half thickness =d{sub e}=c/ω{sub pe}), tearing mode instability dominates. In its nonlinear evolution, it leads to the formation of oblique current channels. Magnetic field lines form 3-D magnetic spirals. Even in the absence of initial guide field, the out-of-reconnection-plane magnetic field generated by the tearing instability itself may play the role of guide field in the growth of secondary finite-guide-field instabilities. For thicker current sheets (half thickness ∼5 d{sub e}), both tearing and non-tearing modes grow. Due to the non-tearing mode, current sheet becomes corrugated in the beginning of the evolution. In this case, tearing mode lets the magnetic field reconnect in the corrugated ECS. Later thick ECS develops filamentary structures and turbulence in which reconnection occurs. This evolution of thick ECS provides an example of reconnection in self-generated turbulence. The power spectra for both the thin and thick current sheets are anisotropic with respect to the electron flow direction. The cascade towards shorter scales occurs preferentially in the direction perpendicular to the electron flow.

  20. Instabilities in sensory processes (United States)

    Balakrishnan, J.


    In any organism there are different kinds of sensory receptors for detecting the various, distinct stimuli through which its external environment may impinge upon it. These receptors convey these stimuli in different ways to an organism's information processing region enabling it to distinctly perceive the varied sensations and to respond to them. The behavior of cells and their response to stimuli may be captured through simple mathematical models employing regulatory feedback mechanisms. We argue that the sensory processes such as olfaction function optimally by operating in the close proximity of dynamical instabilities. In the case of coupled neurons, we point out that random disturbances and fluctuations can move their operating point close to certain dynamical instabilities triggering synchronous activity.

  1. Modulation instability: The beginning (United States)

    Noskov, Roman; Belov, Pavel; Kivshar, Yuri


    The study of metal nanoparticles plays a central role in the emerging novel technologies employing optics beyond the diffraction limit. Combining strong surface plasmon resonances, high intrinsic nonlinearities and deeply subwavelength scales, arrays of metal nanoparticles offer a unique playground to develop novel concepts for light manipulation at the nanoscale. Here we suggest a novel principle to control localized optical energy in chains of nonlinear subwavelength metal nanoparticles based on the fundamental nonlinear phenomenon of modulation instability. In particular, we demonstrate that modulation instability can lead to the formation of long-lived standing and moving nonlinear localized modes of several distinct types such as bright and dark solitons, oscillons, and domain walls. We analyze the properties of these nonlinear localized modes and reveal different scenarios of their dynamics including transformation of one type of mode to another. We believe this work paves a way towards the development of nonlinear nanophotonics circuitry.

  2. Instability and internet design

    Directory of Open Access Journals (Sweden)

    Sandra Braman


    Full Text Available Instability - unpredictable but constant change in one’s environment and the means with which one deals with it - has replaced convergence as the focal problem for telecommunications policy in general and internet policy in particular. Those who designed what we now call the internet during the first decade of the effort (1969-1979, who in essence served simultaneously as its policy-makers, developed techniques for coping with instability of value for network designers today and for those involved with any kind of large-scale sociotechnical infrastructure. Analysis of the technical document series that was medium for and record of that design process reveals coping techniques that began with defining the problem and went on to include conceptual labour, social practices, and technical approaches.

  3. Gravitational instabilities of superspinars

    CERN Document Server

    Pani, Paolo; Berti, Emanuele; Cardoso, Vitor


    Superspinars are ultracompact objects whose mass M and angular momentum J violate the Kerr bound (cJ/GM^2>1). Recent studies analyzed the observable consequences of gravitational lensing and accretion around superspinars in astrophysical scenarios. In this paper we investigate the dynamical stability of superspinars to gravitational perturbations, considering either purely reflecting or perfectly absorbing boundary conditions at the "surface" of the superspinar. We find that these objects are unstable independently of the boundary conditions, and that the instability is strongest for relatively small values of the spin. Also, we give a physical interpretation of the various instabilities that we find. Our results (together with the well-known fact that accretion tends to spin superspinars down) imply that superspinars are very unlikely astrophysical alternatives to black holes.

  4. The instability of markets

    CERN Document Server

    Huberman, B A; Huberman, Bernardo A; Youssefmir, Michael


    Recent developments in the global liberalization of equity and currency markets, coupled to advances in trading technologies, are making markets increasingly interdependent. This increased fluidity raises questions about the stability of the international financial system. In this paper, we show that as couplings between stable markets grow, the likelihood of instabilities is increased, leading to a loss of general equilibrium as the system becomes increasingly large and diverse.

  5. Modulation instability: The beginning (United States)

    Zakharov, V. E.; Ostrovsky, L. A.


    We discuss the early history of an important field of “sturm and drang” in modern theory of nonlinear waves. It is demonstrated how scientific demand resulted in independent and almost simultaneous publications by many different authors on modulation instability, a phenomenon resulting in a variety of nonlinear processes such as envelope solitons, envelope shocks, freak waves, etc. Examples from water wave hydrodynamics, electrodynamics, nonlinear optics, and convection theory are given.

  6. Control and simulation of thermoacoustic instabilities (United States)

    Poinsot, Thierry


    Combustion instabilities (CI), due to thermoacoustic coupling between acoustic waves and chemical reaction, constitute a major danger for all combustion systems. They can drive the system to unstable states where the whole combustor can oscillate, vibrate, quench or in extreme cases explode or burn. Such phenomena are commonly observed in the final phases of development programs, leading to major difficulties and significant additional costs. One of the most famous examples of combustion instabilities is the F1 engine of the Apollo program which required more than 1000 engine tests to obtain a stable regime satisfying all other constraints (performance, ignition, etc). CIs constitute one of the most challenging problems in fluid mechanics: they combine turbulence, acoustics, chemistry, unsteady two-phase flow in complex geometries. Since combustion instabilities have been identified (more than hundred years ago), the combustion community has followed two paths: (1) improve our understanding of the phenomena controlling stability to build engines which would be ``stable by design'' and (2) give up on a detailed understanding of mechanisms and add control systems either in open or closed loop devices to inhibit unstable modes. Of course, understanding phenomena driving combustion instabilities to suppress them would be the most satisfying approach but there is no fully reliable theory or numerical method today which can predict whether a combustor will be stable or not before it is fired. This talk will present an overview of combustion instabilities phenomenology before focusing on: (1) active control methods for combustion instabilities and (2) recent methods to predict unstable modes in combustors. These methods are based on recent Large Eddy Simulation codes for compressible reacting flows on HPC systems but we will also describe recent fully analytical methods which provide new insights into unstable modes in annular combustion chambers. Support: European

  7. Carpal instability nondissociative. (United States)

    Wolfe, Scott W; Garcia-Elias, Marc; Kitay, Alison


    Carpal instability nondissociative (CIND) represents a spectrum of conditions characterized by kinematic dysfunction of the proximal carpal row, often associated with a clinical "clunk." CIND is manifested at the midcarpal and/or radiocarpal joints, and it is distinguished from carpal instability dissociative (CID) by the lack of disruption between bones within the same carpal row. There are four major subcategories of CIND: palmar, dorsal, combined, and adaptive. In palmar CIND, instability occurs across the entire proximal carpal row. When nonsurgical management fails, surgical options include arthroscopic thermal capsulorrhaphy, soft-tissue reconstruction, or limited radiocarpal or intercarpal fusions. In dorsal CIND, the capitate subluxates dorsally from its reduced resting position. Dorsal CIND usually responds to nonsurgical management; refractory cases respond to palmar ligament reefing and/or dorsal intercarpal capsulodesis. Combined CIND demonstrates signs of both palmar and dorsal CIND and can be treated with soft-tissue or bony procedures. In adaptive CIND, the volar carpal ligaments are slackened and are less capable of inducing the physiologic shift of the proximal carpal row from flexion into extension as the wrist ulnarly deviates. Treatment of choice is a corrective osteotomy to restore the normal volar tilt of the distal radius.

  8. Chromosomal instability in meningiomas. (United States)

    van Tilborg, Angela A G; Al Allak, Bushra; Velthuizen, Sandra C J M; de Vries, Annie; Kros, Johan M; Avezaat, Cees J J; de Klein, Annelies; Beverloo, H Berna; Zwarthoff, Ellen C


    Approximately 60% of sporadic meningiomas are caused by inactivation of the NF2 tumor suppressor gene on chromosome 22. No causative gene is known for the remaining 40%. Cytogenetic analysis shows that meningiomas caused by inactivation of the NF2 gene can be divided into tumors that show monosomy 22 as the sole abnormality and tumors with a more complex karyotype. Meningiomas not caused by the NF2 gene usually have a diploid karyotype. Here we report that, besides the clonal chromosomal aberrations, the chromosome numbers in many meningiomas varied from one metaphase spread to the other, a feature that is indicative of chromosomal instability. Unexpectedly and regardless of genotype, a subgroup of tumors was observed with an average number of 44.9 chromosomes and little variation in the number of chromosomes per metaphase spread. In addition, a second subgroup was recognized with a hyperdiploid number of chromosomes (average 48.5) and considerable variation in numbers per metaphase. However, this numerical instability resulted in a clonal karyotype with chromosomal gains and losses in addition to loss of chromosome 22 only in meningiomas caused by inactivation of the NF2 gene. In cultured cells of all tumor groups, bi- and multinucleated cells were seen, as well as anaphase bridges, residual chromatid strings, multiple spindle poles, and unseparated chromatids, suggesting defects in the mitotic apparatus or kinetochore. Thus, we conclude that even a benign and slow-growing tumor like a meningioma displays chromosomal instability.

  9. Cooling Effect of the Richtmyer-Meshkov Instability

    CERN Document Server

    Mohseni, F; Succi, S; Herrmann, H J


    We provide numerical evidence that the Richtmyer-Meshkov (RM) instability contributes to the cooling of a relativistic fluid. Due to the presence of jet particles traveling throughout the medium, shock waves are generated in the form of Mach cones. The interaction of multiple shock waves can trigger the RM instability, and we have found that this process leads to a down-cooling of the relativistic fluid. To confirm the cooling effect of the instability, shock tube Richtmyer-Meshkov instability simulations are performed. Additionally, in order to provide an experimental observable of the RM instability resulting from the Mach cone interaction, we measure the two particle correlation function and highlight the effects of the interaction. The simulations have been performed with an improved version of the relativistic lattice Boltzmann model, including general equations of state and external forces.

  10. Instability of Taylor-Couette Flow of Electrorheological Fluid

    Institute of Scientific and Technical Information of China (English)

    PENG Jie; ZHU Ke-Qin


    A linearized instability analysis of Taylor-Couette flow between two rotating concentric cylinders of an electrorheological (ER) fluid is carried out. The ER fluid exhibits a yield stress in addition to the plastic viscosity when an extra electric-field is applied. It can be found that the yield stress plays a dual role in the flow instability.The possibility of the yield surface falling between the cylinders is analysed. Although small waves appeared on the yielded surface is considered, the yielded surface, which has been treated as a free surface, has little effect on the flow instability. The effects of axisymmetric perturbation on the flow instability are presented due to the axisymmetric of the basic flow. The parameterβ in the yield stress formula of the ER fluid is shown to have distinct effects on the flow instability characteristics.

  11. Initiation, ablation, precursor formation, and instability analysis of thin foil liner Z-pinches (United States)

    Blesener, Isaac Curtis

    result because reduced precursor formation is important for fuel compression and heating in MagLIF. Less precursor can also lead to enhanced x-ray production because there is less mass on axis to cushion the conversion of kinetic energy into x-rays during the implosion and stagnation phases. Finally, in the instability studies, it was observed in laser shadow graph images that liners develop a much larger amplitude instability on their outside surface as compared to wire-arrays. This is an important discovery and could be detrimental to liner performance (compression, x-ray production, etc.) because it could lead to enhanced magnetic Rayleigh-Taylor (MRT) instability during the implosion phase. The reason for the larger instability in liners is again probably due to the fact that plasma builds up on the outside of the liners with no where to go. A possible source of the enhanced instability was found using 2D (xy) PERSEUS simulations comparing the results of MHD and Hall MHD simulations. The instability only developed in the Hall MHD case. The 2D nature of the simulation, along with all simulation parameters being equal between the two cases, rules out the possibility of MRT or m=0 for the cause of the instability (in the simulation). It was found that the Hall term was responsible for causing a shear-flow instability that developed later in time to resemble the experimental results.

  12. Lateral dynamic flight stability of a model hoverfly in normal and inclined stroke-plane hovering. (United States)

    Xu, Na; Sun, Mao


    Many insects hover with their wings beating in a horizontal plane ('normal hovering'), while some insects, e.g., hoverflies and dragonflies, hover with inclined stroke-planes. Here, we investigate the lateral dynamic flight stability of a hovering model hoverfly. The aerodynamic derivatives are computed using the method of computational fluid dynamics, and the equations of motion are solved by the techniques of eigenvalue and eigenvector analysis. The following is shown: The flight of the insect is unstable at normal hovering (stroke-plane angle equals 0) and the instability becomes weaker as the stroke-plane angle increases; the flight becomes stable at a relatively large stroke-plane angle (larger than about 24°). As previously shown, the instability at normal hovering is due to a positive roll-moment/side-velocity derivative produced by the 'changing-LEV-axial-velocity' effect. When the stroke-plane angle increases, the wings bend toward the back of the body, and the 'changing-LEV-axial-velocity' effect decreases; in addition, another effect, called the 'changing-relative-velocity' effect (the 'lateral wind', which is due to the side motion of the insect, changes the relative velocity of its wings), becomes increasingly stronger. This causes the roll-moment/side-velocity derivative to first decrease and then become negative, resulting in the above change in stability as a function of the stroke-plane angle.

  13. Electromagnetic instabilities in rotating magnetized viscous objects

    CERN Document Server

    Nekrasov, Anatoly


    We study electromagnetic streaming instabilities in thermal viscous regions of rotating astrophysical objects, such as, magnetized accretion disks, molecular clouds, their cores, and elephant trunks. The obtained results can also be applied to any regions of interstellar medium, where different equilibrium velocities between charged species can arise. We consider a weakly ionized multicomponent plasma consisting of neutrals and magnetized electrons, ions, and dust grains. The effect of perturbation of collisional frequencies due to density perturbations of species is taken into account. We obtain general expressions for perturbed velocities of species involving the thermal pressure and viscosity in the case in which perturbations propagate perpendicular to the background magnetic field. The dispersion relation is derived and investigated for axisymmetric perturbations. New compressible instabilities generated due to different equilibrium velocities of different charged species are found in the cold and therma...

  14. Instabilities in inductive discharges in reactive gases (United States)

    Chabert, Pascal


    High-density inductively coupled plasmas (ICP) are routinely used for etching in the microelectronics industry. Since there is a substantial voltage across the non-resonant inductive coil, a fraction of the discharge power is deposited capacitively. The real inductive discharge can therefore exist in two different modes: the capacitive mode (E mode), for low power, and the inductive mode (H mode), for high power. As the power is increased, transitions from capacitive to inductive modes (E-H transitions) are observed. Tuszewski (Journal of Applied Physics, 1996) found that when operating with reactive gases containing negative ions the transition can be unstable, and a wide range of powers exist where the discharge oscillates between higher and lower electron density states. Later, Lieberman and co-workers (Lieberman et al., Applied Physics Letters 1999, and Chabert et al. Plasma Sources Sci. and Technol. 2001) proposed a model of this instability, based on particle and energy balance, showing the crucial role of negative ions in the instability process. This paper will present recent experimental and theoretical work in this area. Oscillations in the unsaturated radical (CF and CF2 in a CF4 inductive discharge) concentrations were measured during the instability by time-resolved laser induced fluorescence, showing that neutral species dynamics can be significant. On the theoretical side, conditions for the stability of inductive discharges with electronegative gases were derived from the model.

  15. Anticipatory and Compensatory Postural Adjustments in Response to External Lateral Shoulder Perturbations in Subjects with Parkinson's Disease.

    Directory of Open Access Journals (Sweden)

    Alexandre Kretzer E Castro de Azevedo

    Full Text Available The purpose of this study was to investigate the anticipatory (APA and compensatory (CPA postural adjustments in individuals with Parkinson's disease (PD during lateral instability of posture. Twenty-six subjects (13 individuals with PD and 13 healthy matched controls were exposed to predictable lateral postural perturbations. The electromyographic (EMG activity of the lateral muscles and the displacement of the center of pressure (COP were recorded during four time intervals that are typical for postural adjustments, i.e., immediately before (APA1, APA2 and after (CPA1 and CPA2 the postural disturbances. The magnitude of the activity of the lateral muscles in the group with PD was lower only during the CPA time intervals and not during the anticipatory adjustments (APAs. Despite this finding, subjects with PD exhibit smaller COP excursions before and after the disturbance, probably due to lack of flexibility and proprioceptive impairments. The results of this study suggest that postural instability in subjects with PD can be partially explained by decreased postural sway, before and after perturbations, and reduced muscular activity after body disturbances. Our findings can motivate new studies to investigate therapeutic interventions that optimize the use of postural adjustment strategies in subjects with PD.

  16. Interfacial instabilities in vibrated fluids (United States)

    Porter, Jeff; Laverón-Simavilla, Ana; Tinao Perez-Miravete, Ignacio; Fernandez Fraile, Jose Javier


    Vibrations induce a range of different interfacial phenomena in fluid systems depending on the frequency and orientation of the forcing. With gravity, (large) interfaces are approximately flat and there is a qualitative difference between vertical and horizontal forcing. Sufficient vertical forcing produces subharmonic standing waves (Faraday waves) that extend over the whole interface. Horizontal forcing can excite both localized and extended interfacial phenomena. The vibrating solid boundaries act as wavemakers to excite traveling waves (or sloshing modes at low frequencies) but they also drive evanescent bulk modes whose oscillatory pressure gradient can parametrically excite subharmonic surface waves like cross-waves. Depending on the magnitude of the damping and the aspect ratio of the container, these locally generated surfaces waves may interact in the interior resulting in temporal modulation and other complex dynamics. In the case where the interface separates two fluids of different density in, for example, a rectangular container, the mass transfer due to vertical motion near the endwalls requires a counterflow in the interior region that can lead to a Kelvin-Helmholtz type instability and a ``frozen wave" pattern. In microgravity, the dominance of surface forces favors non-flat equilibrium configurations and the distinction between vertical and horizontal applied forcing can be lost. Hysteresis and multiplicity of solutions are more common, especially in non-wetting systems where disconnected (partial) volumes of fluid can be established. Furthermore, the vibrational field contributes a dynamic pressure term that competes with surface tension to select the (time averaged) shape of the surface. These new (quasi-static) surface configurations, known as vibroequilibria, can differ substantially from the hydrostatic state. There is a tendency for the interface to orient perpendicular to the vibrational axis and, in some cases, a bulge or cavity is induced

  17. Modelling Fluidelastic Instability Forces in Tube Arrays (United States)

    Anderson, J. Burns

    Historically, heat exchangers have been among the most failure prone components in nuclear power plants. Most of these failures are due to tube failures as a result of corrosion, fatigue and fretting wear. Fatigue and fretting wear are a result of flow induced vibration through turbulent buffeting and fluidelastic instability mechanisms. Fluidelastic instability is by far the most important and complex mechanism. This research deals with modelling fluidelastic instability and the resulting tube response. The proposed time domain model uses the concept of a flow cell (Hassan & Hayder [16]) to represent the complex flow field inside a shell and tube heat exchanger and accounts for temporal variations in the flow separation points as a result of tube motion. The fluidelastic forces are determined by predicting the attachment lengths. The predicted forces are used to simulate the response of a single flexible tube inside a shell and tube heat exchanger. It was found that accounting for temporal variations in the separation points predicted lower critical flow velocities, than that of fixed attachment and separation points. Once unstable a phase lag is predicted between the fluidelastic forces and tube response. It was determined that the predicted critical flow velocities agreed well with available experimental data. The developed model represents an important step towards a realistic fluidelastic instability model which can be used to design the new generation nuclear steam generators.

  18. Dynamical and secular instability of a self-gravitating rotating cylinder in a toroidal magnetic field (United States)

    Luyten, P. J.


    The oscillations and stability of a homogeneous self-gravitating rotating cylinder in a toroidal magnetic field are investigated. It is assumed that the field is proportional to the distance to the axis of the cylinder. We show the existence of four infinite discreta spectra of magnetic (or rotational) modes. Rotation stabilizes the magnetic m = 1 instability. The magnetic field decreases the growth rate of rotational instability and reduces the interval of unstable wavenumbers. If m = 1, instability always occurs with the exception of the equipartition state. If m> 1, the instability can be suppressed by a sufficiently large magnetic field. Resistivity decreases the growth rate of magnetic instability, but increases the growth rate of rotational instability. For zero wavenumber perturbations secular instability occurs due to the action of resistivity before a neutral point is attained where a second secular instabiliity initiates due to the action of resistivity


    Energy Technology Data Exchange (ETDEWEB)

    Wheeler, J. Craig [Department of Astronomy, University of Texas at Austin, Austin, TX (United States); Kagan, Daniel [Racah Institute of Physics, Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Chatzopoulos, Emmanouil, E-mail: [Department of Astronomy and Astrophysics and FLASH Center for Computational Science, University of Chicago, Chicago, IL 60637 (United States)


    The magnetorotational instability (MRI) is key to physics in accretion disks and is widely considered to play some role in massive star core collapse. Models of rotating massive stars naturally develop very strong shear at composition boundaries, a necessary condition for MRI instability, and the MRI is subject to triply diffusive destabilizing effects in radiative regions. We have used the MESA stellar evolution code to compute magnetic effects due to the Spruit-Tayler (ST) mechanism and the MRI, separately and together, in a sample of massive star models. We find that the MRI can be active in the later stages of massive star evolution, leading to mixing effects that are not captured in models that neglect the MRI. The MRI and related magnetorotational effects can move models of given zero-age main sequence mass across ''boundaries'' from degenerate CO cores to degenerate O/Ne/Mg cores and from degenerate O/Ne/Mg cores to iron cores, thus affecting the final evolution and the physics of core collapse. The MRI acting alone can slow the rotation of the inner core in general agreement with the observed ''initial'' rotation rates of pulsars. The MRI analysis suggests that localized fields ∼10{sup 12} G may exist at the boundary of the iron core. With both the ST and MRI mechanisms active in the 20 M {sub ☉} model, we find that the helium shell mixes entirely out into the envelope. Enhanced mixing could yield a population of yellow or even blue supergiant supernova progenitors that would not be standard SN IIP.

  20. Reactive-infiltration instabilities in rocks. Fracture dissolution

    CERN Document Server

    Szymczak, Piotr


    A reactive fluid dissolving the surface of a uniform fracture will trigger an instability in the dissolution front, leading to spontaneous formation of pronounced well-spaced channels in the surrounding rock matrix. Although the underlying mechanism is similar to the wormhole instability in porous rocks there are significant differences in the physics, due to the absence of a steadily propagating reaction front. In previous work we have described the geophysical implications of this instability in regard to the formation of long conduits in soluble rocks. Here we describe a more general linear stability analysis, including axial diffusion, transport limited dissolution, non-linear kinetics, and a finite length system.

  1. Sedimentation and gravitational instability of Escherichia coli Suspension (United States)

    Douarche, Carine; Salin, Dominique; Collaboration between Laboratory FAST; LPS Collaboration


    The successive run and tumble of Escherichia coli bacteria provides an active matter suspension of rod-like particles with a large swimming diffusion. As opposed to inactive elongated particles, this diffusion prevents clustering and instability in the gravity field. We measure the time dependent E . coli concentration profile during their sedimentation. After some hours, due to the dioxygen consumption, a motile / non-motile front forms leading to a Rayleigh-Taylor type gravitational instability. Analyzing both sedimentation and instability in the framework of active particle suspensions, we can measure the relevant bacteria hydrodynamic characteristics such as its single particle sedimentation velocity and its hindrance volume.

  2. Electrokinetic Instability near Charge-Selective Hydrophobic Surfaces

    CERN Document Server

    Shelistov, V S; Ganchenko, G S


    The influence of the texture of a hydrophobic surface on the electro-osmotic slip of the second kind and the electrokinetic instability near charge-selective surfaces (permselective membranes, electrodes, or systems of micro- and nanochannels) is investigated theoretically using a simple model based on the Rubinstein-Zaltzman approach. A simple formula is derived to evaluate the decrease in the instability threshold due to hydrophobicity. The study is complemented by numerical investigations both of linear and nonlinear instabilities near a hydrophobic membrane surface. Theory predicts a significant enhancement of the ion flux to the surface and shows a good qualitative agreement with the available experimental data.

  3. Plasma transport driven by the Rayleigh-Taylor instability (United States)

    Ma, X.; Delamere, P. A.; Otto, A.


    Two important differences between the giant magnetospheres (i.e., Jupiter's and Saturn's magnetospheres) and the terrestrial magnetosphere are the internal plasma sources and the fast planetary rotation. Thus, there must be a radially outward flow to transport the plasma to avoid infinite accumulation of plasma. This radial outflow also carries the magnetic flux away from the inner magnetosphere due to the frozen-in condition. As such, there also must be a radial inward flow to refill the magnetic flux in the inner magnetosphere. Due to the similarity between Rayleigh-Taylor (RT) instability and the centrifugal instability, we use a three-dimensional RT instability to demonstrate that an interchange instability can form a convection flow pattern, locally twisting the magnetic flux, consequently forming a pair of high-latitude reconnection sites. This process exchanges a part of the flux tube, thereby transporting the plasma radially outward without requiring significant latitudinal convection of magnetic flux in the ionosphere.

  4. Limitation of the ECRIS performance by kinetic plasma instabilities (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, O., E-mail:; Kalvas, T.; Koivisto, H.; Komppula, J.; Kronholm, R.; Laulainen, J. [Department of Physics, University of Jyväskylä, 40500 Jyväskylä (Finland); Izotov, I.; Mansfeld, D. [Institute of Applied Physics, RAS, 46 Ul’yanova St., 603950 Nizhny Novgorod (Russian Federation); Skalyga, V. [Institute of Applied Physics, RAS, 46 Ul’yanova St., 603950 Nizhny Novgorod (Russian Federation); Lobachevsky State University of Nizhny Novgorod (UNN), 23 Gagarina St., 603950 Nizhny Novgorod (Russian Federation); Toivanen, V. [European Organization for Nuclear Research (CERN), 1211 Geneva 23 (Switzerland); Machicoane, G. [National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, Michigan 48824 (United States)


    Electron cyclotron resonance ion source (ECRIS) plasmas are prone to kinetic instabilities due to anisotropic electron velocity distribution. The instabilities are associated with strong microwave emission and periodic bursts of energetic electrons escaping the magnetic confinement. The instabilities explain the periodic ms-scale oscillation of the extracted beam current observed with several high performance ECRISs and restrict the parameter space available for the optimization of extracted beam currents of highly charged ions. Experiments with the JYFL 14 GHz ECRIS have demonstrated that due to the instabilities the optimum B{sub min}-field is less than 0.8B{sub ECR}, which is the value suggested by the semiempirical scaling laws guiding the design of ECRISs.

  5. Beam instability in 980-nm power lasers: Experiment and analysis (United States)

    Guthrie, James; Tan, G. L.; Ohkubo, M.; Fukushima, T.; Ikegami, Y.; Ijichi, T.; Irikawa, M.; Mand, R. S.; Xu, J. M.


    A theoretical analysis of beam instability (steering), commonly observed in high power ridge waveguide laser diodes is presented. A physical model of multiple interfering lateral modes is proposed and implemented in a two-dimensional self-consistent numerical code. It is shown that the dynamic evolution of the effective waveguide and the coherent lasing of emergent multiple lateral modes of the waveguide under high injection could lead to beam steering and knees in the fiber coupled L-I characteristics. The theory of simultaneous lasing and interaction between several lateral modes is found to be consistent with the observed back-plane radiation image.

  6. Arthroscopic and open management of posterolateral rotatory instability of the elbow. (United States)

    O'Brien, Michael J; Savoie, Felix H


    Posterolateral rotatory instability (PLRI) is the most common cause of residual instability following a simple elbow dislocation. PLRI may result from trauma or iatrogenic injury to the radial ulnohumeral ligament during treatment for other conditions, such as lateral epicondylitis. PLRI can be identified through a combination of history and physical examination, and confirmed with magnetic resonance imaging arthrography. Once diagnosed, surgery is necessary to correct persistent instability. Instability can be confirmed arthroscopically through several findings, including subluxation of the radial head on the capitellum and the arthroscopic "drive through sign of the elbow." Acute repairs, both open and arthroscopic, heal with excellent patient outcomes. In the chronic setting, graft reconstruction may be required. This report describes arthroscopic repair of the radial ulnohumeral ligament and open reconstruction with associated outcomes. A high index of suspicion is necessary to correctly diagnosis this condition in patients with lateral elbow pain and feelings of instability.

  7. Modulational instability of nematic phase

    Indian Academy of Sciences (India)

    T Mithun; K Porsezian


    We numerically observe the effect of homogeneous magnetic field on the modulationally stable case of polar phase in = 2 spinor Bose–Einstein condensates (BECs). Also we investigate the modulational instability of uniaxial and biaxial (BN) states of polar phase. Our observations show that the magnetic field triggers the modulational instability and demonstrate that irrespective of the magnetic field effect the uniaxial and biaxial nematic phases show modulational instability.

  8. Political Instability and Economic Growth


    Swagel, Phillip; Roubini, Nouriel; Ozler, Sule; Alesina, Alberto


    This paper investigates the relationship between political instability and per capita GDP growth in a sample of 113 countries for the period 1950-1982. We define ?political instability? as the propensity of a government collapse, and we estimate a model in which political instability and economic growth are jointly determined. The main result of this paper is that in countries and time periods with a high propensity of government collapse, growth is significantly lower than otherwise. This ef...

  9. Weibel instability with nonextensive distribution

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, Hui-Bin; Liu, Shi-Bing [Strong-field and Ultrafast Photonics Lab, Institute of Laser Engineering, Beijing University of Technology, Beijing 100124 (China)


    Weibel instability in plasma, where the ion distribution is isotropic and the electron component of the plasma possesses the anisotropic temperature distribution, is investigated based on the kinetic theory in context of nonextensive statistics mechanics. The instability growth rate is shown to be dependent on the nonextensive parameters of both electron and ion, and in the extensive limit, the result in Maxwellian distribution plasma is recovered. The instability growth rate is found to be enhanced as the nonextensive parameter of electron increases.

  10. Material instability hazards in mine-processing operations

    Energy Technology Data Exchange (ETDEWEB)

    Fredland, J.W.; Wu, K.K.; Kirkwood, D.W.


    Many accidents occur in the mining industry as a result of the instability of material during handling and processing operation. Accidents due to dump point instability at stockpiles, and at spoil or waste piles, for example, occur with alarming frequency. Miners must be trained to be better aware of these hazards. Information on safe working procedures at stockpiles and surge piles is provided. Mine operators must review their training and operating procedures regularly to ensure that hazardous conditions are avoided.

  11. Instabilities in mimetic matter perturbations (United States)

    Firouzjahi, Hassan; Gorji, Mohammad Ali; Mansoori, Seyed Ali Hosseini


    We study cosmological perturbations in mimetic matter scenario with a general higher derivative function. We calculate the quadratic action and show that both the kinetic term and the gradient term have the wrong sings. We perform the analysis in both comoving and Newtonian gauges and confirm that the Hamiltonians and the associated instabilities are consistent with each other in both gauges. The existence of instabilities is independent of the specific form of higher derivative function which generates gradients for mimetic field perturbations. It is verified that the ghost instability in mimetic perturbations is not associated with the higher derivative instabilities such as the Ostrogradsky ghost.

  12. [Aspirin suppresses microsatellite instability]. (United States)

    Wallinger, S; Dietmaier, W; Beyser, K; Bocker, T; Hofstädter, F; Fishel, R; Rüschoff, J


    Nonsteroidal anti-inflammatory drugs (NSAIDs) exhibit cancer preventive effects and have been shown to induce regression of adenomas in FAP patients. In order to elucidate the probable underlying mechanism, the effect of NSAIDs on mismatch repair related microsatellite instability was investigated. Six colorectal cancer cell lines all but one deficient for human mismatch repair (MMR) genes were examined for microsatellite instability (MSI) prior and after treatment with Aspirin or Sulindac. For rapid in vitro analysis of MSI a microcloning assay was developed by combining Laser microdissection and random (PEP-) PCR prior to specific MSI-PCR. Effects of NSAIDs on cell cycle and apoptosis were systematically investigated by using flow cytometry and cell-sorting. MSI frequency in cells deficient of MMR genes (hMSH2, hMLH1, hMSH6) was markedly reduced after long-term (> 10 weeks) NSAID treatment. This effect was reversible, time- and concentration dependent. However, in the hPMS2 deficient endometrial cancer cell line (HEC-1-A) the MSI phenotype kept unchanged. According to cell sorting, non-apoptotic cells were stable and apoptotic cells were unstable. These results suggest that aspirin/sulindac induces a genetic selection for microsatellite stability in a subset of MMR-deficient cells and may thus provide an effective prophylactic therapy for HNPCC related colorectal carcinomas.

  13. Instability of enclosed horizons

    CERN Document Server

    Kay, Bernard S


    We study the classical massless scalar wave equation on the region of 1+1-dimensional Minkowski space between the two branches of the hyperbola $x^2-t^2=1$ with vanishing boundary conditions on it. We point out that there are initially finite-energy initially, say, right-going waves for which the stress-energy tensor becomes singular on the null-line $t+x=0$. We also construct the quantum theory of this system and show that, while there is a regular Hartle-Hawking-Israel-like state, there are coherent states built on this for which there is a similar singularity in the expectation value of the renormalized stress-energy tensor. We conjecture that in 1+3-dimensional situations with 'enclosed horizons' such as a (maximally extended) Schwarzschild black hole in equilibrium in a stationary box or the (maximally extended) Schwarzschild-AdS spacetime, there will be a similar singularity at the horizon and that would signal an instability when matter perturbations and/or gravity are switched on. Such an instability ...

  14. Libration driven multipolar instabilities

    CERN Document Server

    Cébron, David; Herreman, Wietze


    We consider rotating flows in non-axisymmetric enclosures that are driven by libration, i.e. by a small periodic modulation of the rotation rate. Thanks to its simplicity, this model is relevant to various contexts, from industrial containers (with small oscillations of the rotation rate) to fluid layers of terrestial planets (with length-of-day variations). Assuming a multipolar $n$-fold boundary deformation, we first obtain the two-dimensional basic flow. We then perform a short-wavelength local stability analysis of the basic flow, showing that an instability may occur in three dimensions. We christen it the Libration Driven Multipolar Instability (LDMI). The growth rates of the LDMI are computed by a Floquet analysis in a systematic way, and compared to analytical expressions obtained by perturbation methods. We then focus on the simplest geometry allowing the LDMI, a librating deformed cylinder. To take into account viscous and confinement effects, we perform a global stability analysis, which shows that...

  15. Tennis Elbow (Lateral Epicondylitis) (United States)

    .org Tennis Elbow (Lateral Epicondylitis) Page ( 1 ) Tennis elbow, or lateral epicondyliti s, is a painful condition of the elbow caused by overuse. Not surprisingly, playing tennis or other racquet sports can cause ...

  16. The Study of Thermal Conditions on Weibel Instability

    Directory of Open Access Journals (Sweden)

    M. Mahdavi


    Full Text Available Weibel electromagnetic instability has been studied analytically in relativistic plasma with high parallel temperature, where |α=(mc2/T∥(1+p^⊥2/m2c21/2|≪1 and while the collision effects of electron-ion scattering have also been considered. According to these conditions, an analytical expression is derived for the growth rate of the Weibel instability for a limiting case of |ζ=α/2(ω′/ck|≪1, where ω′ is the sum of the wave frequency of instability and the collision frequency of electrons with background ions. The results show that in the limiting condition α≪1 there is an unusual situation of the Weibel instability so that T∥≫T⊥, while in the classic Weibel instability T∥≪T⊥. The obtained results show that the growth rate of the Weibel instability will be decreased due to an increase in the number of collisions and a decrease in the anisotropic temperature by the increasing of plasma density, while the increase of the parameter γ^⊥=(1+p^⊥2/m2c21/2 leads to the increase of the Weibel instability growth rate.

  17. Bony instability of the shoulder. (United States)

    Bushnell, Brandon D; Creighton, R Alexander; Herring, Marion M


    Instability of the shoulder is a common problem treated by many orthopaedists. Instability can result from baseline intrinsic ligamentous laxity or a traumatic event-often a dislocation that injures the stabilizing structures of the glenohumeral joint. Many cases involve soft-tissue injury only and can be treated successfully with repair of the labrum and ligamentous tissues. Both open and arthroscopic approaches have been well described, with recent studies of arthroscopic soft-tissue techniques reporting results equal to those of the more traditional open techniques. Over the last decade, attention has focused on the concept of instability of the shoulder mediated by bony pathology such as a large bony Bankart lesion or an engaging Hill-Sachs lesion. Recent literature has identified unrecognized large bony lesions as a primary cause of failure of arthroscopic reconstruction for instability, a major cause of recurrent instability, and a difficult diagnosis to make. Thus, although such bony lesions may be relatively rare compared with soft-tissue pathology, they constitute a critically important entity in the management of shoulder instability. Smaller bony lesions may be amenable to arthroscopic treatment, but larger lesions often require open surgery to prevent recurrent instability. This article reviews recent developments in the diagnosis and treatment of bony instability.

  18. Cinerama sickness and postural instability

    NARCIS (Netherlands)

    Bos, J.E.; Ledegang, W.D.; Lubeck, A.J.A.; Stins, J.F.


    Motion sickness symptoms and increased postural instability induced by motion pictures have been reported in a laboratory, but not in a real cinema. We, therefore, carried out an observational study recording sickness severity and postural instability in 19 subjects before, immediately and 45 min af

  19. Instability and Information

    CERN Document Server

    Patzelt, Felix


    Many complex systems exhibit extreme events far more often than expected for a normal distribution. This work examines how self-similar bursts of activity across several orders of magnitude can emerge from first principles in systems that adapt to information. Surprising connections are found between two apparently unrelated research topics: hand-eye coordination in balancing tasks and speculative trading in financial markets. Seemingly paradoxically, locally minimising fluctuations can increase a dynamical system's sensitivity to unpredictable perturbations and thereby facilitate global catastrophes. This general principle is studied in several domain-specific models and in behavioural experiments. It explains many findings in both fields and resolves an apparent antinomy: the coexistence of stabilising control or market efficiency and perpetual instabilities resembling critical phenomena in physical systems.

  20. Structural and Material Instability

    DEFF Research Database (Denmark)

    Cifuentes, Gustavo Cifuentes

    This work is a small contribution to the general problem of structural and material instability. In this work, the main subject is the analysis of cracking and failure of structural elements made from quasi-brittle materials like concrete. The analysis is made using the finite element method. Three...... use of interface elements) is used successfully to model cases where the path of the discontinuity is known in advance, as is the case of the analysis of pull-out of fibers embedded in a concrete matrix. This method is applied to the case of non-straight fibers and fibers with forces that have....... Numerical problems associated with the use of elements with embedded cracks based on the extended finite element method are presented in the next part of this work. And an alternative procedure is used in order to successfully remove these numerical problems. In the final part of this work, a computer...

  1. The bar instability revisited

    CERN Document Server

    Chiodi, Filippo; Claudin, Philippe


    The river bar instability is revisited, using a hydrodynamical model based on Reynolds averaged Navier-Stokes equations. The results are contrasted with the standard analysis based on shallow water Saint-Venant equations. We first show that the stability of both transverse modes (ripples) and of small wavelength inclined modes (bars) predicted by the Saint-Venant approach are artefacts of this hydrodynamical approximation. When using a more reliable hydrodynamical model, the dispersion relation does not present any maximum of the growth rate when the sediment transport is assumed to be locally saturated. The analysis therefore reveals the fundamental importance of the relaxation of sediment transport towards equilibrium as it it is responsible for the stabilisation of small wavelength modes. This dynamical mechanism is characterised by the saturation number, defined as the ratio of the saturation length to the water depth Lsat/H. This dimensionless number controls the transition from ripples (transverse patte...

  2. Baroclinic Instability on Hot Extrasolar Planets

    CERN Document Server

    Polichtchouk, Inna


    We investigate baroclinic instability in flow conditions relevant to hot extrasolar planets. The instability is important for transporting and mixing heat, as well as for influencing large-scale variability on the planets. Both linear normal mode analysis and non-linear initial value calculations are carried out -- focusing on the freely-evolving, adiabatic situation. Using a high-resolution general circulation model (GCM) which solves the traditional primitive equations, we show that large-scale jets similar to those observed in current GCM simulations of hot extrasolar giant planets are likely to be baroclinically unstable on a timescale of few to few tens of planetary rotations, generating cyclones and anticyclones that drive weather systems. The growth rate and scale of the most unstable mode obtained in the linear analysis are in qualitative, good agreement with the full non-linear calculations. In general, unstable jets evolve differently depending on their signs (eastward or westward), due to the chang...

  3. Simple model with damping of the mode-coupling instability

    Energy Technology Data Exchange (ETDEWEB)

    Pestrikov, D.V. [AN SSSR, Novosibirsk (Russian Federation). Inst. Yadernoj Fiziki


    In this paper we use a simple model to study the suppression of the transverse mode-coupling instability. Two possibilities are considered. One is due to the damping of particular synchrobetatron modes, and another - due to Landau damping, caused by the nonlinearity of betatron oscillations. (author)

  4. The arm posture in children with unilateral Cerebral Palsy is mainly related to antero-posterior gait instability. (United States)

    Meyns, Pieter; Duysens, Jacques; Desloovere, Kaat


    In this observational case-control study we aimed to determine whether altered arm postures in children with unilateral CP (uniCP) are related to gait instability in a specific direction. Antero-posterior and medio-lateral Foot Placement Estimator instability measures and arm posture measures (vertical and antero-posterior hand position, sagittal and frontal upper arm elevation angle) were determined in eleven uniCP (7 years-10 months) and twenty-four typically developing children (9 years-6 months) at two walking speeds. Spearman-rank correlation analyses were made to examine the relationship between antero-posterior and medio-lateral arm posture and gait instability. Arm posture in both planes was related to antero-posterior instability (e.g. sagittal and frontal upper arm elevation angle correlated moderately with antero-posterior instability; R=0.41, pposture in uniCP may be a compensation to reduce antero-posterior gait instability.

  5. Beam instability Workshop - plenary sessions

    Energy Technology Data Exchange (ETDEWEB)



    The purpose of this workshop was to provide a review of the mechanisms of limiting beam instabilities, their cures, including feedback, and beam measurement for synchrotron radiation light sources. 12 plenary sessions took place whose titles are: 1) challenging brilliance and lifetime issues with increasing currents; 2) limiting instabilities in multibunch; 3) experience from high currents in B factories; 4) longitudinal dynamics in high intensity/bunch; 5) Transverse instabilities for high intensity/bunch; 6) working group introduction from ESRF experience; 7) impedance modelling: simulations, minimization; 8) report on the broadband impedance measurements and modelling workshop; 9) feedback systems for synchrotron light sources; 10) beam instabilities diagnostics; 11) harmonic cavities: the pros and cons; and 12) experimental study of fast beam-ion instabilities at PLS. This document gathers the 12 articles that were presented during these sessions.

  6. Equilibrium Electro-osmotic Instability

    CERN Document Server

    Rubinstein, Isaak


    Since its prediction fifteen years ago, electro-osmotic instability has been attributed to non-equilibrium electro-osmosis related to the extended space charge which develops at the limiting current in the course of concentration polarization at a charge-selective interface. This attribution had a double basis. Firstly, it has been recognized that equilibrium electro-osmosis cannot yield instability for a perfectly charge-selective solid. Secondly, it has been shown that non-equilibrium electro-osmosis can. First theoretical studies in which electro-osmotic instability was predicted and analyzed employed the assumption of perfect charge-selectivity for the sake of simplicity and so did the subsequent numerical studies of various time-dependent and nonlinear features of electro-osmotic instability. In this letter, we show that relaxing the assumption of perfect charge-selectivity (tantamount to fixing the electrochemical potential in the solid) allows for equilibrium electro-osmotic instability. Moreover, we s...

  7. Instability in Shocked Granular Gases

    CERN Document Server

    Sirmas, Nick; Radulescu, Matei


    Shocks in granular media, such as vertically oscillated beds, have been shown to develop instabilities. Similar jet formation has been observed in explosively dispersed granular media. Our previous work addressed this instability by performing discrete-particle simulations of inelastic media undergoing shock compression. By allowing finite dissipation within the shock wave, instability manifests itself as distinctive high density non-uniformities and convective rolls within the shock structure. In the present study we have extended this work to investigate this instability at the continuum level. We modeled the Euler equations for granular gases with a modified cooling rate to include an impact velocity threshold necessary for inelastic collisions. Our results showed a fair agreement between the continuum and discrete-particle models. Discrepancies, such as higher frequency instabilities in our continuum results may be attributed to the absence of higher order effects.

  8. Instability in shocked granular gases (United States)

    Sirmas, Nick; Falle, Sam; Radulescu, Matei


    Shocks in granular media, such as vertically oscillated beds, have been shown to develop instabilities. Similar jet formation has been observed in explosively dispersed granular media. Our previous work addressed this instability by performing discrete-particle simulations of inelastic media undergoing shock compression. By allowing finite dissipation within the shock wave, instability manifests itself as distinctive high density non-uniformities and convective rolls within the shock structure. In the present study we have extended this work to investigate this instability at the continuum level. We modeled the Euler equations for granular gases with a modified cooling rate to include an impact velocity threshold necessary for inelastic collisions. Our results showed a fair agreement between the continuum and discrete-particle models. Discrepancies, such as higher frequency instabilities in our continuum results may be attributed to the absence of higher order effects.

  9. Gravitational Instabilities in Circumstellar Disks

    CERN Document Server

    Kratter, Kaitlin M


    [Abridged] Star and planet formation are the complex outcomes of gravitational collapse and angular momentum transport mediated by protostellar and protoplanetary disks. In this review we focus on the role of gravitational instability in this process. We begin with a brief overview of the observational evidence for massive disks that might be subject to gravitational instability, and then highlight the diverse ways in which the instability manifests itself in protostellar and protoplanetary disks: the generation of spiral arms, small scale turbulence-like density fluctuations, and fragmentation of the disk itself. We present the analytic theory that describes the linear growth phase of the instability, supplemented with a survey of numerical simulations that aim to capture the non-linear evolution. We emphasize the role of thermodynamics and large scale infall in controlling the outcome of the instability. Despite apparent controversies in the literature, we show a remarkable level of agreement between analyt...

  10. MHD instabilities developing in a conductor exploding in the skin effect mode (United States)

    Oreshkin, V. I.; Chaikovsky, S. A.; Datsko, I. M.; Labetskaya, N. A.; Mesyats, G. A.; Oreshkin, E. V.; Ratakhin, N. A.; Rybka, D. V.


    The results of experiments with exploding copper conductors, performed on the MIG facility (providing currents of amplitude of about 2.5 MA and rise time of 100 ns), are analyzed. With an frame optical camera, large-scale instabilities of wavelength 0.2-0.5 mm were detected on the conductor surface. The instabilities show up as plasma "tongues" expanding with a sound velocity in the opposite direction to the magnetic field gradient. Analysis performed using a two-dimensional MHD code has shown that the structures observed in the experiments were formed most probably due to flute instabilities. The growth of flute instabilities is predetermined by the development of thermal instabilities near the conductor surface. The thermal instabilities arise behind the front of the nonlinear magnetic diffusion wave propagating through the conductor. The wavefront on its own is not subject to thermal instabilities.

  11. An Adaptive Instability Suppression Controls Method for Aircraft Gas Turbine Engine Combustors (United States)

    Kopasakis, George; DeLaat, John C.; Chang, Clarence T.


    An adaptive controls method for instability suppression in gas turbine engine combustors has been developed and successfully tested with a realistic aircraft engine combustor rig. This testing was part of a program that demonstrated, for the first time, successful active combustor instability control in an aircraft gas turbine engine-like environment. The controls method is called Adaptive Sliding Phasor Averaged Control. Testing of the control method has been conducted in an experimental rig with different configurations designed to simulate combustors with instabilities of about 530 and 315 Hz. Results demonstrate the effectiveness of this method in suppressing combustor instabilities. In addition, a dramatic improvement in suppression of the instability was achieved by focusing control on the second harmonic of the instability. This is believed to be due to a phenomena discovered and reported earlier, the so called Intra-Harmonic Coupling. These results may have implications for future research in combustor instability control.

  12. Three-Dimensional Dynamical Instabilities in Galactic Ionization Fronts

    CERN Document Server

    Whalen, D J; Whalen, Daniel J.; Norman, Michael L.


    Ionization front instabilities have long been of interest for their suspected role in a variety of phenomena in the galaxy, from the formation of bright rims and 'elephant trunks' in nebulae to triggered star formation in molecular clouds. Numerical treatments of these instabilities have historically been limited in both dimensionality and input physics, leaving important questions about their true evolution unanswered. We present the first three-dimensional radiation hydrodynamical calculations of both R-type and D-type ionization front instabilities in galactic environments (i.e., solar metallicity gas). Consistent with linear stability analyses of planar D-type fronts, our models exhibit many short-wavelength perturbations growing at early times that later evolve into fewer large-wavelength structures. The simulations demonstrate that both self-consistent radiative transfer and three-dimensional flow introduce significant morphological differences to unstable modes when compared to earlier two-dimensional ...

  13. Clinical forms of shoulder instability in pediatric patients

    Directory of Open Access Journals (Sweden)

    Yaroslav N. Proshchenko


    Full Text Available Background. The recurrence rate of adolescent chronic shoulder instability is approximately 56%–68%. However, this pathology is often missed in childhood and adolescence. Aim. To identify the clinical forms of shoulder joint instability in pediatric patients. Materials and methods. The authors present the data from 57 pediatric patients aged 3−17 years with a total of 61 unstable shoulder joints. All patients were divided into groups according to the form of instability. Traumatic chronic shoulder instability was identified in 40 patients (Bankart and Hill–Sachs injuries. Of these, non-traumatic shoulder instability was diagnose in 17, including five with recurrent dislocation, and spontaneous shoulder dislocation due to dysplasia of glenoid and labrum was diagnosed in 12. Of the 57 patients in the study cohort, 53 underwent surgery. Postoperatively, two patients developed recurrent shoulder dislocation (Andreev–Boichev technique due type III shoulder dysplasia in the first patient and multidirectional injury in the second. Conclusions. Shoulder joint instability should be considered as the traumatic or non-traumatic form. Treatment decisions should be based on anatomical characteristics that predispose to recurrent dislocation.

  14. CHF Enhancement by Surface Patterning based on Hydrodynamic Instability Model

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Han; Bang, In Cheol [UNIST, Ulsan (Korea, Republic of)


    If the power density of a device exceeds the CHF point, bubbles and vapor films will be covered on the whole heater surface. Because vapor films have much lower heat transfer capabilities compared to the liquid layer, the temperature of the heater surface will increase rapidly, and the device could be damaged due to the heater burnout. Therefore, the prediction and the enhancement of the CHF are essential to maximizing the efficient heat removal region. Numerous studies have been conducted to describe the CHF phenomenon, such as hydrodynamic instability theory, macrolayer dryout theory, hot/dry spot theory, and bubble interaction theory. The hydrodynamic instability model, proposed by Zuber, is the predominant CHF model that Helmholtz instability attributed to the CHF. Zuber assumed that the Rayleigh-Taylor (RT) instability wavelength is related to the Helmholtz wavelength. Lienhard and Dhir proposed a CHF model that Helmholtz instability wavelength is equal to the most dangerous RT wavelength. In addition, they showed the heater size effect using various heater surfaces. Lu et al. proposed a modified hydrodynamic theory that the Helmholtz instability was assumed to be the heater size and the area of the vapor column was used as a fitting factor. The modified hydrodynamic theories were based on the change of Helmholtz wavelength related to the RT instability wavelength. In the present study, the change of the RT instability wavelength, based on the heater surface modification, was conducted to show the CHF enhancement based on the heater surface patterning in a plate pool boiling. Sapphire glass was used as a base heater substrate, and the Pt film was used as a heating source. The patterning surface was based on the change of RT instability wavelength. In the present work the study of the CHF was conducted using bare Pt and patterned heating surfaces.

  15. [Lateral lumbar disk hernia]. (United States)

    Monod, A; Desmoineaux, P; Deburge, A


    Lateral lumbar disc herniations (L.D.H.) develop in the foramen, and compress the nerve root against the overlying vertebral pedicle. In our study of L.D.H. from the clinical, radiographical, and therapeutical aspects, we reviewed 23 cases selected from the 590 patients treated for discal herniation from 1984 to 1987. The frequency of L.D.H. in this series was 3.8 per cent. The clinical pattern brings out some suggestive signs of L.D.H. (frequency of cruralgia, a seldom very positive Lasegue's test, the paucity of spinal signs, non impulsive pain). Saccoradiculography and discography rarely evidenced the L.D.H.. The T.D.M. was the investigation of choice on condition that it was correctly used. When the image was doubtful, disco-CT confirmation should be proceeded too. This latter method of investigation enabled the possibility of sequestration to be explored. 14 patients were treated by chemonucleolysis, with 9 successful outcomes. The 5 failures were cases where chemonucleolysis should not have been indicated, mainly due to associated osseous stenosis. 9 patients underwent immediate surgery with good results in each case.

  16. Abelianization of QCD plasma instabilities (United States)

    Arnold, Peter; Lenaghan, Jonathan


    QCD plasma instabilities appear to play an important role in the equilibration of quark-gluon plasmas in heavy-ion collisions in the theoretical limit of weak coupling (i.e. asymptotically high energy). It is important to understand what nonlinear physics eventually stops the exponential growth of unstable modes. It is already known that the initial growth of plasma instabilities in QCD closely parallels that in QED. However, once the unstable modes of the gauge fields grow large enough for non-Abelian interactions between them to become important, one might guess that the dynamics of QCD plasma instabilities and QED plasma instabilities become very different. In this paper, we give suggestive arguments that non-Abelian self-interactions between the unstable modes are ineffective at stopping instability growth, and that the growing non-Abelian gauge fields become approximately Abelian after a certain stage in their growth. This in turn suggests that understanding the development of QCD plasma instabilities in the nonlinear regime may have close parallels to similar processes in traditional plasma physics. We conjecture that the physics of collisionless plasma instabilities in SU(2) and SU(3) gauge theory becomes equivalent, respectively, to (i) traditional plasma physics, which is U(1) gauge theory, and (ii) plasma physics of U(1)×U(1) gauge theory.

  17. The arm posture in children with unilateral Cerebral Palsy is mainly related to antero-posterior gait instability

    NARCIS (Netherlands)

    Meyns, P.; Duysens, J.; Desloovere, K.


    In this observational case-control study we aimed to determine whether altered arm postures in children with unilateral CP (uniCP) are related to gait instability in a specific direction. Antero-posterior and medio-lateral Foot Placement Estimator instability measures and arm posture measures (verti

  18. Three-Dimensional Dynamical Instabilities in Galactic Ionization Fronts (United States)

    Whalen, Daniel J.; Norman, Michael L.


    Ionization front instabilities have long been of interest for their suspected role in a variety of phenomena in the Galaxy, from the formation of bright rims and "elephant trunks" in nebulae to triggered star formation in molecular clouds. Numerical treatments of these instabilities have historically been limited in both dimensionality and input physics, leaving important questions about their true evolution unanswered. We present the first three-dimensional radiation hydrodynamical calculations of both R-type (rarefied) and D-type (dense) ionization front instabilities in Galactic environments (i.e., solar-metallicity gas). Consistent with linear stability analyses of planar D-type fronts, our models exhibit many short-wavelength perturbations that grow at early times and later evolve into fewer large-wavelength structures. The simulations demonstrate that both self-consistent radiative transfer and three-dimensional flow introduce significant morphological differences to unstable modes when compared to earlier two-dimensional approximate models. We find that the amplitude of the instabilities in the nonlinear regime is primarily determined by the efficiency of cooling within the shocked neutral shell. Strong radiative cooling leads to long, extended structures with pronounced clumping, while weaker cooling leads to saturated modes that devolve into turbulent flows. These results suggest that expanding H II regions may either promote or provide turbulent support against the formation of later generations of stars, with potential consequences for star formation rates in the Galaxy today.

  19. Instability of ties in compression

    DEFF Research Database (Denmark)

    Buch-Hansen, Thomas Cornelius


    Masonry cavity walls are loaded by wind pressure and vertical load from upper floors. These loads results in bending moments and compression forces in the ties connecting the outer and the inner wall in a cavity wall. Large cavity walls are furthermore loaded by differential movements from...... exact instability solutions are complex to derive, not to mention the extra complexity introducing dimensional instability from the temperature gradients. Using an inverse variable substitution and comparing an exact theory with an analytical instability solution a method to design tie...

  20. Microsatellite instability in bladder cancer

    DEFF Research Database (Denmark)

    Gonzalez-Zulueta, M; Ruppert, J M; Tokino, K;


    Somatic instability at microsatellite repeats was detected in 6 of 200 transitional cell carcinomas of the bladder. Instabilities were apparent as changes in (GT)n repeat lengths on human chromosome 9 for four tumors and as alterations in a (CAG)n repeat in the androgen receptor gene on the X...... chromosome for three tumors. Single locus alterations were detected in three tumors, while three other tumors revealed changes in two or more loci. In one tumor we found microsatellite instability in all five loci analyzed on chromosome 9. The alterations detected were either minor 2-base pair changes...

  1. Sawtooth Instability in the Compact Toroidal Hybrid (United States)

    Herfindal, J. L.; Maurer, D. A.; Hartwell, G. J.; Ennis, D. A.; Knowlton, S. F.


    Sawtooth instabilities have been observed in the Compact Toroidal Hybrid (CTH), a current-carrying stellarator/tokamak hybrid device. The sawtooth instability is driven by ohmic heating of the core plasma until the safety factor drops below unity resulting in the growth of an m = 1 kink-tearing mode. Experiments varying the vacuum rotational transform from 0.02 to 0.13 are being conducted to study sawtooth property dependance on vacuum flux surface structure. The frequency of the sawtooth oscillations increase from 2 kHz to 2.8 kHz solely due the decrease in rise time of the oscillation, the crash time is unchanged. CTH has three two-color SXR cameras, a three-channel 1mm interferometer, and a new bolometer system capable of detecting the signatures of sawtooth instabilities. The new bolometer system consists of two cameras, each containing a pair of diode arrays viewing the plasma directly or through a beryllium filter. Electron temperature measurements are found with the two-color SXR cameras through a ratio of the SXR intensities. Impurity radiation can drastically affect the electron temperature measurement, therefore new filters consisting of aluminum and carbon were selected to avoid problematic line radiation while maximizing the signal for a 100 eV plasma. This work is supported by U.S. Department of Energy Grant No. DE-FG02-00ER54610.

  2. Superradiant instability of the Kerr brane

    CERN Document Server

    Ishibashi, Akihiro; Gualtieri, Leonardo; Cardoso, Vitor


    We consider linear gravitational perturbations of the Kerr brane, an exact solution of vacuum Einstein's equations in dimensions higher than four and a low-energy solution of string theory. Decomposing the perturbations in tensor harmonics of the transverse Ricci-flat space, we show that tensor- and vector-type metric perturbations of the Kerr brane satisfy respectively a massive Klein-Gordon equation and a Proca equation on the four-dimensional Kerr space, where the mass term is proportional to the eigenvalue of the harmonics. Massive bosonic fields trigger a well-known superradiant instability on a Kerr black hole. We thus establish that Kerr branes in dimensions $D\\geq6$ are gravitationally unstable due to superradiance. These solutions are also unstable against the Gregory-Laflamme instability and we discuss the conditions for either instability to occur and their rather different nature. When the transverse dimensions are compactified and much smaller than the Kerr horizon, only the superradiant instabil...

  3. Hydrodynamics of pedestrians' instability in floodwaters (United States)

    Arrighi, Chiara; Oumeraci, Hocine; Castelli, Fabio


    People's safety is the first objective to be fulfilled by flood risk mitigation measures, and according to existing reports on the causes of casualties, most of the fatalities are due to inappropriate behaviour such as walking or driving in floodwaters. Currently available experimental data on people instability in floodwaters suffer from a large dispersion primarily depending on the large variability of the physical characteristics of the subjects. This paper introduces a dimensionless mobility parameter θP for people partly immersed in flood flows, which accounts for both flood and subject characteristics. The parameter θP is capable of identifying a unique threshold of instability depending on a Froude number, thus reducing the scatter of existing experimental data. Moreover, a three-dimensional (3-D) numerical model describing the detailed geometry of a human body and reproducing a selection of critical pairs of water depth and velocity is presented. The numerical results in terms of hydrodynamic forces and force coefficients are analysed and discussed. Both the mobility parameter θP and the numerical results hint at the crucial role of the Froude number and relative submergence as the most relevant dimensionless numbers to interpret the loss of stability. Finally, the mobility parameter θP is compared with an analogous dimensionless parameter for vehicles' instability in floodwaters, providing a new contribution to support flood risk management and educating people.

  4. Subject to Instability

    Directory of Open Access Journals (Sweden)

    Karen Bouwer


    Full Text Available For Plantier, language constitutes reality and is male dominated. Readers of texts, she says, are at a disadvantage because the author imposes a logic that we must accept in order to understand the text. The discourses shaping our social reality have the same effect. Plantier has struggled against individual voices, discourses, and the very fabric of language informed by these discourses. "Subject to Instability" examines the impact on her generic evolution of a changing sense of self, of who her interlocutors are, and of those for whom she is speaking. I argue that her increasing attempt to juggle many different voices destabilizes her "monologic," poetical voice, resulting in a blurring of generic boundaries and eventually the abandonment of poetry. Recognizing that our entry into language is a form of alienation also unsettles Plantier because it undermines the very identity that allows her to speak for others. She concludes that each woman needs to become a Subject in her own right, but she continues to struggle against dominant discourses, modeling "resisting reader" strategies. If she can no longer practice "monologic steadfastness," this does not deter her from attempting to dismantle patriarchal language and striving to make her voice prevail over others.

  5. Treatment options for patellofemoral instability in sports traumatology

    Directory of Open Access Journals (Sweden)

    Philippe M. Tscholl


    Full Text Available Patellofemoral instability not only involves lateral patellar dislocation, patellar mal-tracking or subluxation but can also cause a limiting disability for sports activities. Its underlying causes are known as morphological anomalies of the patellofemoral joint or the mechanical axis, femorotibial malrotation, variants of the knee extensor apparatus, and ligamentous insufficiencies often accompanied by poor proprioception. Athletes with such predisposing factors are either suffering from unspecific anterior knee pain or from slightly traumatic or recurrent lateral patellar dislocation Treatment options of patellar instability are vast, and need to be tailored individually depending on the athlete’s history, age, complaints and physical demands. Different conservative and surgical treatment options are reviewed and discussed, especially limited expectations after surgery.

  6. Numerical analysis of anisotropic diffusion effect on ICF hydrodynamic instabilities

    Directory of Open Access Journals (Sweden)

    Olazabal-Loumé M.


    Full Text Available The effect of anisotropic diffusion on hydrodynamic instabilities in the context of Inertial Confinement Fusion (ICF flows is numerically assessed. This anisotropy occurs in indirect-drive when laminated ablators are used to modify the lateral transport [1,2]. In direct-drive, non-local transport mechanisms and magnetic fields may modify the lateral conduction [3]. In this work, numerical simulations obtained with the code PERLE [4], dedicated to linear stability analysis, are compared with previous theoretical results [5]. In these approaches, the diffusion anisotropy can be controlled by a characteristic coefficient which enables a comprehensive study. This work provides new results on the ablative Rayleigh-Taylor (RT, ablative Richtmyer-Meshkov (RM and Darrieus-Landau (DL instabilities.

  7. Nernst advection and the field-generating thermal instability revisited (United States)

    Bissell, J. J.


    It is widely held that the Nernst effect can drive instability in un-magnetised laser-plasmas by laterally compressing seed B-fields arising from the field-generating thermal instability [Tidman & Shanny, Phys. Fluids, 12:1207 (1974)]. Indeed, for wavelike perturbations, differential compression by the Nernst mechanism is thought to be most pronounced in the limit of low wave-number k -> 0, and is considered particularly important given that it can ostensibly lead to instability when the more usual field-generating mechanism is stable. However, as part of a recent article [Bissell et al., New J. Phys., 15:025017 (2013)] we noted some irregularities to the Nernst mechanism which obscure its operation. For example, by taking characteristic density and temperature length-scales ln and lT respectively, we observed that consistent analytical treatment of the instability requires kln,T >> 1, preventing the peak-growth limit k -> 0. Furthermore, the Nernst term-which compresses magnetic field perturbations-does not couple to a corresponding term acting on thermal perturbations, and as such does not describe an unstable feedback mechanism. In this article we probe the origin of such ambiguities more formally, and in so doing argue (contrary to reports existing elsewhere in the literature) that the Nernst effect does not drive instability in un-magnetised conditions, at least not in the fashion typically cited.

  8. Atlantoaxial instability in Down's syndrome


    J Gordon Millichap


    The radiographs and clinical evaluations of 90 children with Down’s syndrome were reassessed after an interval of 5 years in a study of atlantoaxial instability (AAI) at the Derbyshire Children’s Hospital and Infirmary, Derby, UK.

  9. Evaporative instabilities in climbing films (United States)

    Hosoi, A. E.; Bush, John W. M.


    We consider flow in a thin film generated by partially submerging an inclined rigid plate in a reservoir of ethanol or methanol water solution and wetting its surface. Evaporation leads to concentration and surface tension gradients that drive flow up the plate. An experimental study indicates that the climbing film is subject to two distinct instabilities. The first is a convective instability characterized by flattened convection rolls aligned in the direction of flow and accompanied by free-surface deformations; in the meniscus region, this instability gives rise to pronounced ridge structures aligned with the mean flow. The second instability, evident when the plate is nearly vertical, takes the form of transverse surface waves propagating up the plate.

  10. Intrinsic Instability of Coronal Streamers

    CERN Document Server

    Chen, Y; Song, H Q; Shi, Q Q; Feng, S W; Xia, L D; 10.1088/0004-637X/691/2/1936


    Plasma blobs are observed to be weak density enhancements as radially stretched structures emerging from the cusps of quiescent coronal streamers. In this paper, it is suggested that the formation of blobs is a consequence of an intrinsic instability of coronal streamers occurring at a very localized region around the cusp. The evolutionary process of the instability, as revealed in our calculations, can be described as follows: (1) through the localized cusp region where the field is too weak to sustain the confinement, plasmas expand and stretch the closed field lines radially outward as a result of the freezing-in effect of plasma-magnetic field coupling; the expansion brings a strong velocity gradient into the slow wind regime providing the free energy necessary for the onset of a subsequent magnetohydrodynamic instability; (2) the instability manifests itself mainly as mixed streaming sausage-kink modes, the former results in pinches of elongated magnetic loops to provoke reconnections at one or many loc...

  11. Material Instabilities in Particulate Systems (United States)

    Goddard, J. D.


    Following is a brief summary of a theoretical investigation of material (or constitutive) instability associated with shear induced particle migration in dense particulate suspensions or granular media. It is shown that one can obtain a fairly general linear-stability analysis, including the effects of shear-induced anisotropy in the base flow as well as Reynolds dilatancy. A criterion is presented here for simple shearing instability in the absence of inertia and dilatancy.

  12. Instability following total knee arthroplasty. (United States)

    Rodriguez-Merchan, E Carlos


    Background Knee prosthesis instability (KPI) is a frequent cause of failure of total knee arthroplasty. Moreover, the degree of constraint required to achieve immediate and long-term stability in total knee arthroplasty (TKA) is frequently debated. Questions This review aims to define the problem, analyze risk factors, and review strategies for prevention and treatment of KPI. Methods A PubMed (MEDLINE) search of the years 2000 to 2010 was performed using two key words: TKA and instability. One hundred and sixty-five initial articles were identified. The most important (17) articles as judged by the author were selected for this review. The main criteria for selection were that the articles addressed and provided solutions to the diagnosis and treatment of KPI. Results Patient-related risk factors predisposing to post-operative instability include deformity requiring a large surgical correction and aggressive ligament release, general or regional neuromuscular pathology, and hip or foot deformities. KPI can be prevented in most cases with appropriate selection of implants and good surgical technique. When ligament instability is anticipated post-operatively, the need for implants with a greater degree of constraint should be anticipated. In patients without significant varus or valgus malalignment and without significant flexion contracture, the posterior cruciate ligament (PCL) can be retained. However, the PCL should be sacrificed when deformity exists particularly in patients with rheumatoid arthritis, previous patellectomy, previous high tibial osteotomy or distal femoral osteotomy, and posttraumatic osteoarthritis with disruption of the PCL. In most cases, KPI requires revision surgery. Successful outcomes can only be obtained if the cause of KPI is identified and addressed. Conclusions Instability following TKA is a common cause of the need for revision. Typically, knees with deformity, rheumatoid arthritis, previous patellectomy or high tibial osteotomy, and

  13. Midcarpal instability: a radiological perspective

    Energy Technology Data Exchange (ETDEWEB)

    Toms, Andoni Paul [Norfolk and Norwich University Hospital NHS Trust, Department of Radiology, Norwich, Norfolk (United Kingdom); Radiology Academy, Cotman Centre, Norwich, Norfolk (United Kingdom); Chojnowski, Adrian [Norfolk and Norwich University Hospital NHS Trust, Department of Orthopaedic Surgery, Norwich, Norfolk (United Kingdom); Cahir, John G. [Norfolk and Norwich University Hospital NHS Trust, Department of Radiology, Norwich, Norfolk (United Kingdom)


    Midcarpal instability (MCI) is the result of complex abnormal carpal motion at the midcarpal joint of the wrist. It is a form of non-dissociative carpal instability (CIND) and can be caused by various combinations of extrinsic ligament injuries that then result in one of several subtypes of MCI. The complex patterns of injury and the kinematics are further complicated by competing theories, terminology and classifications of MCI. Palmar, dorsal, ulna midcarpal instability, and capitolunate or chronic capitolunate instability are all descriptions of types of MCI with often overlapping features. Palmar midcarpal instability (PMCI) is the most commonly reported type of MCI. It has been described as resulting from deficiencies in the ulna limb of the palmar arcuate ligament (triquetrohamate-capitate) or the dorsal radiotriquetral ligaments, or both. Unstable carpal articulations can be treated with limited carpal arthrodesis or the ligamentous defects can be treated with capsulorrhaphy or ligament reconstruction. Conventional radiographic abnormalities are usually limited to volar intercalated segment instability (VISI) patterns of carpal alignment and are not specific. For many years stress view radiographs and videofluoroscopy have been the methods of choice for demonstrating carpal instability and abnormal carpal kinematics respectively. Dynamic US can be also used to demonstrate midcarpal dyskinesia including the characteristic triquetral ''catch-up'' clunk. Tears of the extrinsic ligaments can be demonstrated with MR arthrography, and probably with CT arthrography, but intact yet redundant ligaments are more difficult to identify. The exact role of these investigations in the diagnosis, categorisation and management of midcarpal instability has yet to be determined. (orig.)

  14. Vector-Resonance-Multimode Instability (United States)

    Sergeyev, S. V.; Kbashi, H.; Tarasov, N.; Loiko, Yu.; Kolpakov, S. A.


    The modulation and multimode instabilities are the main mechanisms which drive spontaneous spatial and temporal pattern formation in a vast number of nonlinear systems ranging from biology to laser physics. Using an Er-doped fiber laser as a test bed, here for the first time we demonstrate both experimentally and theoretically a new type of a low-threshold vector-resonance-multimode instability which inherits features of multimode and modulation instabilities. The same as for the multimode instability, a large number of longitudinal modes can be excited without mode synchronization. To enable modulation instability, we modulate the state of polarization of the lasing signal with the period of the beat length by an adjustment of the in-cavity birefringence and the state of polarization of the pump wave. As a result, we show the regime's tunability from complex oscillatory to periodic with longitudinal mode synchronization in the case of resonance matching between the beat and cavity lengths. Apart from the interest in laser physics for unlocking the tunability and stability of dynamic regimes, the proposed mechanism of the vector-resonance-multimode instability can be of fundamental interest for the nonlinear dynamics of various distributed systems.

  15. Elastocapillary instability under partial wetting conditions: bending versus buckling

    CERN Document Server

    Andreotti, Bruno; Das, Siddhartha; Snoeijer, Jacco H


    The elastocapillary instability of a flexible plate plunged in a liquid bath is analysed theoretically. We show that the plate can bend due to two separate destabilizing mechanisms, when the liquid is partially wetting the solid. For contact angles $\\theta_e > \\pi/2$, the capillary forces acting tangential to the surface are compressing the plate and can induce a classical buckling instability. However, a second mechanism appears due to capillary forces normal to surface. These induce a destabilizing torque that tends to bend the plate for any value of the contact angle $\\theta_e > 0$. We denote these mechanisms as "buckling" and "bending" respectively and identify the two corresponding dimensionless parameters that govern the elastocapillary stability. The onset of instability is determined analytically and the different bifurcation scenarios are worked out for experimentally relevant conditions.

  16. The chromo-Weibel instability in an expanding background

    CERN Document Server

    Attems, Maximilian; Strickland, Michael


    In this proceedings contribution we review recent calculations of the dynamics of the chromo-Weibel instability in the quark gluon plasma. This instability is present in gauge theories with a one-particle distribution function which is momentum-space anisotropic in the local rest frame. The conditions necessary for triggering this instability can be present already in the color-glass-condensate initial state or dynamically generated by the rapid longitudinal expansion of the matter created in a heavy-ion collision. Using the hard-loop framework we study the case that the one-particle distribution function possesses an arbitrary initial momentum anisotropy that increases in time due to longitudinal free streaming. The resulting three-dimensional dynamical equations for the chromofield evolution are solved numerically. We find that there is regeneration of the longitudinal pressure due to unstable plasma modes; nevertheless, the system seems to maintain a high-degree of momentum-space anisotropy. Despite this a...

  17. A stiff collar can restrict atlantoaxial instability in rheumatoid cervical spine in selected cases.


    Kauppi, M; Anttila, P.


    OBJECTIVE--To study the efficiency of a stiff collar in restricting the instability of anterior atlantoaxial subluxation (AAS). METHODS--Twenty two successive patients with an unstable AAS were studied. Lateral view radiographs were taken of the cervical spine in flexion, extension, and neutral positions without a collar, and in full flexion with a custom made stiff collar. RESULTS--The collar restricted more than 30% of the maximal instability of the AAS in 50% of the patients. These patient...

  18. Temporal variation of meandering intensity and domain-wide lateral oscillations of the Gulf Stream (United States)

    Lee, Tong; Cornillon, Peter


    The path of the Gulf Stream exhibits two modes of variability: wavelike spatial meanders associated with instability processes and large-sale lateral shifts of the path presumably due to atmospheric forcing. The objectives of this study are to examine the temporal variation of the intensity of spatial meandering in the stream, to characterize large-scale lateral oscillations in the stream's path, and to study the correlation betwen these two dynamically distinct modes of variability. The data used for this analysis are path displacemets ofthe Gulf Stream between 75 deg and 60 deg W obtained from AVHRR-derived (Advanced Very High Resolution Radiometer) infrared images for the period April 1982 through December 1989. Meandering intensity, measured by the spatial root-mean-sqaure displacement of the stream path, displays a 9-month dominant periodicity which is persistent through the study period. The 9-month fluctuation in meandering intensity may be related to the interaction of Rosseby waves with the stream. Interannual variation of meandering intensity is also found to be significant, with meandering being mich more intense during 1985 than it was in 1987. Annual variation, however,is weak and not well-defined.The spatially averaged position of the stream, which reflects nonmeandering large-scale lateral oscillations of the stream path, is dominated by an annual cycle. On average, the mean position is farthest north in November and farthest south in April. The first empirical orthogonal function mode of the space-time path displacements represents lateral oscillatins that are in-phase over the space-time domain. Interannual oscillations are also observed and are found to be weaker than the annual oscillation. The eigenvalue of the first mode indicates that about 21.5% of the total space-time variability of the stream path can be attibuted to domain-wide lateral oscillation. The correlation between meandering intensity and domain-wide lateral oscillations is very

  19. Spinal instability in ankylosing spondylitis

    Directory of Open Access Journals (Sweden)

    Badve Siddharth


    Full Text Available Background: Unstable spinal lesions in patients with ankylosing spondylitis are common and have a high incidence of associated neurological deficit. The evolution and presentation of these lesions is unclear and the management strategies can be confusing. We present retrospective analysis of the cases of ankylosing spondylitis developing spinal instability either due to spondylodiscitis or fractures for mechanisms of injury, presentations, management strategies and outcome. Materials and Methods: In a retrospective analysis of 16 cases of ankylosing spondylitis, treated surgically for unstable spinal lesions over a period of 12 years (1995-2007; 87.5% (n=14 patients had low energy (no obvious/trivial trauma while 12.5% (n=2 patients sustained high energy trauma. The most common presentation was pain associated with neurological deficit. The surgical indications included neurological deficit, chronic pain due to instability and progressive deformity. All patients were treated surgically with anterior surgery in 18.8% (n=3 patients, posterior in 56.2% (n=9 patients and combined approach in 25% (n=4 patients. Instrumented fusion was carried out in 87.5% (n=14 patients. Average surgical duration was 3.84 (Range 2-7.5 hours, blood loss 765.6 (± 472.5 ml and follow-up 54.5 (Range 18-54 months. The patients were evaluated for pain score, Frankel neurological grading, deformity progression and radiological fusion. One patient died of medical complications a week following surgery. Results: Intra-operative adverse events like dural tears and inadequate deformity correction occurred in 18.7% (n=3 patients (Cases 6, 7 and 8 which could be managed conservatively. There was a significant improvement in the Visual analogue score for pain from a pre-surgical median of 8 to post-surgical median of 2 (P=0.001, while the neurological status improved in 90% (n=9 patients among those with preoperative neurological deficit who could be followed-up (n =10. Frankel

  20. Lateral epicondylitis and beyond: imaging of lateral elbow pain with clinical-radiologic correlation. (United States)

    Kotnis, Nikhil A; Chiavaras, Mary M; Harish, Srinivasan


    The diagnosis of lateral epicondylitis is often straightforward and can be made on the basis of clinical findings. However, radiological assessment is valuable where the clinical picture is less clear or where symptoms are refractory to treatment. Demographics, aspects of clinical history, or certain physical signs may suggest an alternate diagnosis. Knowledge of the typical clinical presentation and imaging findings of lateral epicondylitis, in addition to other potential causes of lateral elbow pain, is necessary. These include entrapment of the posterior interosseous and lateral antebrachial cutaneous nerves, posterolateral rotatory instability, posterolateral plica syndrome, Panner's disease, osteochondritis dissecans of the capitellum, radiocapitellar overload syndrome, occult fractures and chondral-osseous impaction injuries, and radiocapitellar arthritis. Knowledge of these potential masquerades of lateral epicondylitis and their characteristic clinical and imaging features is essential for accurate diagnosis. The goal of this review is to provide an approach to the imaging of lateral elbow pain, discussing the relevant anatomy, various causes, and discriminating factors, which will allow for an accurate diagnosis.

  1. Lateral epicondylitis and beyond: imaging of lateral elbow pain with clinical-radiologic correlation

    Energy Technology Data Exchange (ETDEWEB)

    Kotnis, Nikhil A. [McMaster University, Departments of Radiology, Hamilton, ON (Canada); Sheffield Teaching Hospitals, Department of Medical Physics and Medical Imaging, Sheffield (United Kingdom); Chiavaras, Mary M. [McMaster University, Departments of Radiology, Hamilton, ON (Canada); Harish, Srinivasan [McMaster University, Departments of Radiology, Hamilton, ON (Canada); St. Joseph' s Healthcare, Department of Diagnostic Imaging, Hamilton, ON (Canada)


    The diagnosis of lateral epicondylitis is often straightforward and can be made on the basis of clinical findings. However, radiological assessment is valuable where the clinical picture is less clear or where symptoms are refractory to treatment. Demographics, aspects of clinical history, or certain physical signs may suggest an alternate diagnosis. Knowledge of the typical clinical presentation and imaging findings of lateral epicondylitis, in addition to other potential causes of lateral elbow pain, is necessary. These include entrapment of the posterior interosseous and lateral antebrachial cutaneous nerves, posterolateral rotatory instability, posterolateral plica syndrome, Panner's disease, osteochondritis dissecans of the capitellum, radiocapitellar overload syndrome, occult fractures and chondral-osseous impaction injuries, and radiocapitellar arthritis. Knowledge of these potential masquerades of lateral epicondylitis and their characteristic clinical and imaging features is essential for accurate diagnosis. The goal of this review is to provide an approach to the imaging of lateral elbow pain, discussing the relevant anatomy, various causes, and discriminating factors, which will allow for an accurate diagnosis. (orig.)

  2. Elliptic and magneto-elliptic instabilities

    Directory of Open Access Journals (Sweden)

    Lyra Wladimir


    Full Text Available Vortices are the fundamental units of turbulent flow. Understanding their stability properties therefore provides fundamental insights on the nature of turbulence itself. In this contribution I briely review the phenomenological aspects of the instability of elliptic streamlines, in the hydro (elliptic instability and hydromagnetic (magneto-elliptic instability regimes. Vortex survival in disks is a balance between vortex destruction by these mechanisms, and vortex production by others, namely, the Rossby wave instability and the baroclinic instability.

  3. Evaluation Of Patellar Tracking During Knee Range Of Motion In Patients With Patellar Lateralization And Normal Subjects

    Directory of Open Access Journals (Sweden)

    Goharpei S


    Full Text Available Background: Patellofemoral joint disorders are the most common cause of anterior knee pain in patients who referred to orthopedic clinics. Patellar lateralization cause anterior knee pain due to weakness of vastus medialis oblique muscle or tightness of lateral structures like lateral retinaculum or iliotibial band muscle. Materials and Methods: For evaluation of this abnormality, plane radiography, CT scan and MRI are useful. In plane radiography only one view in a single joint position can be obtained, because of that it is not a good method to detect abnormal tracking during knee range of motion. The purpose of this study was to evaluate patellar tracking by kinematics MRI during five serial degrees of knee range of motion (40, 30, 20, 10, 0 degrees in 30 patients with patellar lateralization and 10 normal subjects, aged 18-30 years. Results and Conclusion: tistical analysis showed that in patients group, patella had the most stability in 40 degree of knee flexion and this stability reduced when knee reached to full extension. At this point, patella moved laterally and the most instability was seen during 20 to 0 degree of knee extension.

  4. Observation of transverse instabilities in the FNAL 200 MeV Linac

    Energy Technology Data Exchange (ETDEWEB)

    McCrory, E.; Lee, G.; Webber, R.C.


    Using newly installed Beam Position Monitors in the downstream half of the FNAL Linac, we have observed significant transverse beam instabilities within the 30 beam pulse. We can affect the instability so that the peak-to-peak amplitude is as small as 0.5 mm or as large as 8 mm. The effect is largely due to a beam-plasma instability in the ten-meter 750-keV transport line. Other causes are being investigated. Using these instabilities as an analysis tool, the betatron amplitude of the beam has been reduced. 7 refs., 4 figs.

  5. Amyotrophic Lateral Sclerosis (ALS) (United States)

    ... ALS Neurons' broken machinery piles up in ALS Esclerosis Lateral Amiotrófica Dormant viral genes may awaken to ... Dementia Information Page Multifocal Motor Neuropathy Information Page Multiple Sclerosis Information Page Muscular Dystrophy Information Page Myasthenia ...

  6. Amyotrophic lateral sclerosis (ALS) (United States)

    Lou Gehrig disease; ALS; Upper and lower motor neuron disease; Motor neuron disease ... 98. Shaw PJ. Amyotrophic lateral sclerosis and other motor neuron diseases. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  7. Manipulation of interfacial instabilities by using a soft, deformable solid layer

    Indian Academy of Sciences (India)

    Gaurav; V Shankar


    Multilayer flows are oftensusceptible to interfacial instabilities caused due to jump in viscosity/elasticity across thefluid–fluid interface. It is frequently required to manipulate and control these interfacial instabilities in various applications such as coating processes or polymer coextrusion. We demonstrate here the possibility of using a deformable solid coating to control such interfacial instabilities for various flow configurations and for different fluid rheological behaviors. In particular, we show complete suppression of interfacial flow instabilities by making the walls sufficiently deformable when the configuration was otherwise unstable for the case of flow past a rigid surface. While these interfacial instabilities could be suppressed in certain parameter regimes, it is also possible to enhance the flow instabilities by tuning the shear modulus of the deformable solid coating for other ranges of parameters.

  8. Rayleigh-Taylor Instability in a Relativistic Fireball on a Moving Computational Grid

    CERN Document Server

    Duffell, Paul C


    We numerically calculate the growth and saturation of the Rayleigh-Taylor instability caused by the deceleration of relativistic outflows with Lorentz factor \\Gamma = 10, 30, and 100. The instability generates turbulence whose scale exhibits strong dependence on Lorentz factor, as only modes within the causality scale \\Delta \\theta ~ 1/\\Gamma can grow. We develop a simple diagnostic to measure the fraction of energy in turbulent eddies and use it to estimate magnetic field amplification by the instability. We estimate a magnetic energy fraction ~ 0.01 due to Rayleigh-Taylor turbulence in a shock-heated region behind the forward shock. The instability completely disrupts the contact discontinuity between the ejecta and the swept up circumburst medium. The reverse shock is stable, but is impacted by the Rayleigh-Taylor instability, which strengthens the reverse shock and pushes it away from the forward shock. The forward shock front is unaffected by the instability, but Rayleigh-Taylor fingers can penetrate abo...

  9. Zinc and cadmium accumulation in cabbage aphid(Brevicoryne brassicae)host plants and developmental instability

    Institute of Scientific and Technical Information of China (English)

    Gazi G(o)rür


    Developmental instability in morphological characters can occur during individual development due to various environmental stresses.Fluctuating asymmetry (FA)is often used as a measurement of developmental instability.but within-environment variation(cve)is also considered an indicator of developmental instability.Cabbage aphid nated cabbage and radish plants.Developmental instability indicators were measured and their relations with fitness were explored.Results revealed that cabbage aphids exposed to Cd and Zn displayed considerable developmental instability,particularly fluctuating asymmetry.Differences in developmental instability between the two metals were also detected,as well as differences between the two developmental instability measurements.For almost all measured traits.FA was greater on Cd-and Zn-contaminated compared to non-contaminated host plants.In contrast.CV of some traits was greater on non-contami-nated host plants,yet for Otller traits CV Was greater on contaminated host plants.There were also non-significant inverse relationships between FA and fitness of cabbage aphid populations.Due to weak correlations between FA and different patterns of two developmental instability measurements,this study does not support the hypothesis that developmental instability is a useful bioindicator of environmental quality.

  10. Full-Scale Cyclic Testing of Deep Slender Wide-Flange Steel Beam-Columns under Unidirectional and Bidirectional Lateral Drift Demands


    Elkady, Ahmed Mohamed Ahmed; Lignos, Dimitrios


    Deep and slender wide-flange steel beam-columns are commonly used in steel special moment frames (SMFs) in North America. These sections provide large moment-of-inertia required to satisfy the design code’s drift limits while keeping the column steel weight at minimum. Due to their low out-of-plane moment-of-inertia and high web and flange slenderness ratios, such sections are vulnerable to local and global geometric instabilities when subjected to lateral drift demands coupled with compressi...

  11. Elastocapillary instability under partial wetting conditions: Bending versus buckling

    NARCIS (Netherlands)

    Andreotti, Bruno; Marchand, Antonin; Das, Siddhartha; Snoeijer, Jacco H.


    The elastocapillary instability of a flexible plate plunged in a liquid bath is analyzed theoretically. We show that the plate can bend due to two separate destabilizing mechanisms, when the liquid is partially wetting the solid. For contact angles θe>π/2, the capillary forces acting tangential to t

  12. Instability during bunch shortening of an electron-cooled beam

    Directory of Open Access Journals (Sweden)

    M. Takanaka


    Full Text Available Bunch shortening causes an electron-cooled beam to be space charge dominated at low energies. Instability during the bunch shortening has been studied using a particle-tracking program where the 3D space-charge field due to the beam is calculated with a simplifying model.

  13. Fermi Liquid Instabilities in the Spin Channel

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Congjun; /Santa Barbara, KITP; Sun, Kai; Fradkin, Eduardo; /Illinois U., Urbana; Zhang, Shou-Cheng; /Stanford U., Phys. Dept.


    We study the Fermi surface instabilities of the Pomeranchuk type in the spin triplet channel with high orbital partial waves (F{sub l}{sup a} (l > 0)). The ordered phases are classified into two classes, dubbed the {alpha} and {beta}-phases by analogy to the superfluid {sup 3}He-A and B-phases. The Fermi surfaces in the {alpha}-phases exhibit spontaneous anisotropic distortions, while those in the {beta}-phases remain circular or spherical with topologically non-trivial spin configurations in momentum space. In the {alpha}-phase, the Goldstone modes in the density channel exhibit anisotropic overdamping. The Goldstone modes in the spin channel have nearly isotropic underdamped dispersion relation at small propagating wavevectors. Due to the coupling to the Goldstone modes, the spin wave spectrum develops resonance peaks in both the {alpha} and {beta}-phases, which can be detected in inelastic neutron scattering experiments. In the p-wave channel {beta}-phase, a chiral ground state inhomogeneity is spontaneously generated due to a Lifshitz-like instability in the originally nonchiral systems. Possible experiments to detect these phases are discussed.

  14. Amyotrophic lateral sclerosis

    Directory of Open Access Journals (Sweden)

    Leigh P Nigel


    Full Text Available Abstract Amyotrophic lateral sclerosis (ALS is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. Incidence (average 1.89 per 100,000/year and prevalence (average 5.2 per100,000 are relatively uniform in Western countries, although foci of higher frequency occur in the Western Pacific. The mean age of onset for sporadic ALS is about 60 years. Overall, there is a slight male prevalence (M:F ratio~1.5:1. Approximately two thirds of patients with typical ALS have a spinal form of the disease (limb onset and present with symptoms related to focal muscle weakness and wasting, where the symptoms may start either distally or proximally in the upper and lower limbs. Gradually, spasticity may develop in the weakened atrophic limbs, affecting manual dexterity and gait. Patients with bulbar onset ALS usually present with dysarthria and dysphagia for solid or liquids, and limbs symptoms can develop almost simultaneously with bulbar symptoms, and in the vast majority of cases will occur within 1–2 years. Paralysis is progressive and leads to death due to respiratory failure within 2–3 years for bulbar onset cases and 3–5 years for limb onset ALS cases. Most ALS cases are sporadic but 5–10% of cases are familial, and of these 20% have a mutation of the SOD1 gene and about 2–5% have mutations of the TARDBP (TDP-43 gene. Two percent of apparently sporadic patients have SOD1 mutations, and TARDBP mutations also occur in sporadic cases. The diagnosis is based on clinical history, examination, electromyography, and exclusion of 'ALS-mimics' (e.g. cervical spondylotic myelopathies, multifocal motor neuropathy, Kennedy's disease by appropriate investigations. The pathological hallmarks comprise loss of motor neurones with intraneuronal ubiquitin-immunoreactive inclusions in upper motor neurones and TDP-43

  15. Craving creativity in later life

    DEFF Research Database (Denmark)

    Fristrup, Tine


    The societal norms of ageing and old age are changing in society today, due to demographic changes that favour a pedagogicalization of society, focusing on the management of human resources throughout the entire lifespan. The discourse on active ageing mot only reveals ‘better’ ways of ageing......’ is to be understood according to the interpretations available in different knowledge perspectives in order to discipline the future knowledge production of ageing and control the processes of subjectification in later life as the disciplining of ‘Population Ageing’: Becoming a subject to active ageing. Dominant...

  16. Unusual Spinal Epidural Lipomatosis and Lumbosacral Instability (United States)

    Ruiz Picazo, David; Ramírez Villaescusa, José


    Introduction. Epidural lipomatosis is most frequently observed in patients on chronic steroid treatment. Only a few idiopathic epidural lipomatosis cases have been described. Material and Methods. 64-year-old male patient presented with low back pain and left leg pain. Later, the patient experienced neurogenic claudication and radicular pain in the left leg without urinary dysfunction. Plain radiography and magnetic resonance imaging demonstrated an abnormal fat tissue overgrowth in the epidural space with compression of the dural sac, degenerative disc disease at L4-L5 level, and instability at L5-S1. Endocrinopathic diseases and chronic steroid therapy were excluded. If conservative treatment failed, surgical treatment can be indicated. Results. After surgery, there was a gradual improvement in symptoms and signs, and six months later the patient returned to daily activities and was neurologically normal. Conclusion. In the absence of common causes of neurogenic claudication, epidural lipomatosis should be considered. The standard test for the diagnosis of epidural lipomatosis is magnetic resonance (MR). At first, conservative treatment must be considered; weight loss and the suspension of prior corticosteroid therapy are indicated. In the presence of neurological impairment, the operative treatment of wide surgical decompression must be performed soon after diagnosis. PMID:27069704

  17. Interfacial instabilities and Kapitsa pendula (United States)

    Krieger, Madison


    Determining the critera for onset and amplitude growth of instabilities is one of the central problems of fluid mechanics. We develop a parallel between the Kapitsa effect, in which a pendulum subject to high-frequency low-amplitude vibrations becomes stable in the inverted position, and interfaces separating fluids of different density. It has long been known that such interfaces can be stabilized by vibrations, even when the denser fluid is on top. We demonstrate that the stability diagram for these fluid interfaces is identical to the stability diagram for an appopriate Kapitsa pendulum. We expand the robust, ``dictionary''-type relationship between Kapitsa pendula and interfacial instabilities by considering the classical Rayleigh-Taylor, Kelvin-Helmholtz and Plateau instabilities, as well as less-canonical examples ranging in scale from the micron to the width of a galaxy.

  18. Interfacial Instability during Granular Erosion. (United States)

    Lefebvre, Gautier; Merceron, Aymeric; Jop, Pierre


    The complex interplay between the topography and the erosion and deposition phenomena is a key feature to model granular flows such as landslides. Here, we investigated the instability that develops during the erosion of a wet granular pile by a dry dense granular flow. The morphology and the propagation of the generated steps are analyzed in relation to the specific erosion mechanism. The selected flowing angle of the confined flow on a dry heap appears to play an important role both in the final state of the experiment, and for the shape of the structures. We show that the development of the instability is governed by the inertia of the flow through the Froude number. We model this instability and predict growth rates that are in agreement with the experiment results.

  19. Evaporative Instability in Binary Mixtures (United States)

    Narayanan, Ranga; Uguz, Erdem


    In this talk we depict the physics of evaporative convection for binary systems in the presence of surface tension gradient effects. Two results are of importance. The first is that a binary system, in the absence of gravity, can generate an instability only when heated from the vapor side. This is to be contrasted with the case of a single component where instability can occur only when heated from the liquid side. The second result is that a binary system, in the presence of gravity, will generate an instability when heated from either the vapor or the liquid side provided the heating is strong enough. In addition to these results we show the conditions at which interfacial patterns can occur. Support from NSF OISE 0968313, Partner Univ. Fund and a Chateaubriand Fellowship is acknowledged.

  20. Laboratory blast wave driven instabilities (United States)

    Kuranz, Carolyn


    This presentation discusses experiments involving the evolution of hydrodynamic instabilities in the laboratory under high-energy-density (HED) conditions. These instabilities are driven by blast waves, which occur following a sudden, finite release of energy, and consist of a shock front followed by a rarefaction wave. When a blast wave crosses an interface with a decrease in density, hydrodynamic instabilities will develop. Instabilities evolving under HED conditions are relevant to astrophysics. These experiments include target materials scaled in density to the He/H layer in SN1987A. About 5 kJ of laser energy from the Omega Laser facility irradiates a 150 μm plastic layer that is followed by a low-density foam layer. A blast wave structure similar to those in supernovae is created in the plastic layer. The blast wave crosses an interface having a 2D or 3D sinusoidal structure that serves as a seed perturbation for hydrodynamic instabilities. This produces unstable growth dominated by the Rayleigh-Taylor (RT) instability in the nonlinear regime. We have detected the interface structure under these conditions using x-ray backlighting. Recent advances in our diagnostic techniques have greatly improved the resolution of our x-ray radiographic images. Under certain conditions, the improved images show some mass extending beyond the RT spike and penetrating further than previously observed or predicted by current simulations. The observed effect is potentially of great importance as a source of mass transport to places not anticipated by current theory and simulation. I will discuss the amount of mass in these spike extensions, the associated uncertainties, and hypotheses regarding their origin We also plan to show comparisons of experiments using single mode and multimode as well as 2D and 3D initial conditions. This work is sponsored by DOE/NNSA Research Grants DE-FG52-07NA28058 (Stewardship Sciences Academic Alliances) and DE-FG52-04NA00064 (National Laser User

  1. Filamentation Instability of Counterstreaming Laser-Driven Plasmas (United States)

    Fox, W.; Fiksel, G.; Bhattacharjee, A.; Chang, P.-Y.; Germaschewski, K.; Hu, S. X.; Nilson, P. M.


    Filamentation due to the growth of a Weibel-type instability was observed in the interaction of a pair of counterstreaming, ablatively driven plasma flows, in a supersonic, collisionless regime relevant to astrophysical collisionless shocks. The flows were created by irradiating a pair of opposing plastic (CH) foils with 1.8 kJ, 2-ns laser pulses on the OMEGA EP Laser System. Ultrafast laser-driven proton radiography was used to image the Weibel-generated electromagnetic fields. The experimental observations are in good agreement with the analytical theory of the Weibel instability and with particle-in-cell simulations.

  2. A generalized biharmonic equation and its applications to hydrodynamic instability

    Indian Academy of Sciences (India)

    Mihir B Banerjee; J R Gupta; R G Shandil


    Problems concerning characterization of eigenvalues of some linear and homogenous differential systems by the Pellew and Southwell method of conjugate eigenfunctions in the domain of hydrodynamic instability are discussed and a general mathematical framework described. In this general survey we look back on and rewrite this work almost in exactly the way it evolved out of a few naive looking calculations in hydrodynamic instability. We show in the process the close relationship that exists between mathematical analysis and its applications with due credit to intuition as the main source of mathematical activity.

  3. Waves and instability in a one-dimensional microfluidic array

    CERN Document Server

    Liu, Bin; Feng, Yan


    Motion in a one-dimensional (1D) microfluidic array is simulated. Water droplets, dragged by flowing oil, are arranged in a single row, and due to their hydrodynamic interactions spacing between these droplets oscillates with a wave-like motion that is longitudinal or transverse. The simulation yields wave spectra that agree well with experiment. The wave-like motion has an instability which is confirmed to arise from nonlinearities in the interaction potential. The instability's growth is spatially localized. By selecting an appropriate correlation function, the interaction between the longitudinal and transverse waves is described.

  4. Instabilities, motion and deformation of active fluid droplets (United States)

    Whitfield, Carl A.; Hawkins, Rhoda J.


    We consider two minimal models of active fluid droplets that exhibit complex dynamics including steady motion, deformation, rotation and oscillating motion. First we consider a droplet with a concentration of active contractile matter adsorbed to its boundary. We analytically predict activity driven instabilities in the concentration profile, and compare them to the dynamics we find from simulations. Secondly, we consider a droplet of active polar fluid of constant concentration. In this system we predict, motion and deformation of the droplets in certain activity ranges due to instabilities in the polarisation field. Both these systems show spontaneous transitions to motility and deformation which resemble dynamics of the cell cytoskeleton in animal cells.

  5. Seiberg-Witten Instability of Various Topological Black Holes

    CERN Document Server

    Ong, Yen Chin


    We review the Seiberg-Witten instability of topological black holes in Anti-de Sitter space due to nucleation of brane-anti-brane pairs. We start with black holes in general relativity, and then proceed to discuss the peculiar property of topological black holes in Ho\\v{r}ava-Lifshitz gravity -- they have instabilities that occur at only finite range of distance away from the horizon. This behavior is not unique to black holes in Ho\\v{r}ava-Lifshitz theory, as it is also found in the relatively simple systems of charged black hole with dilaton hair that arise in low energy limit of string theory.

  6. Filamentation instability of counter-streaming laser-driven plasmas

    CERN Document Server

    Fox, W; Bhattacharjee, A; Chang, P -Y; Germaschewski, K; Hu, S X; Nilson, P M


    Filamentation due to the growth of a Weibel-type instability was observed in the interaction of a pair of counter-streaming, ablatively-driven plasma flows, in a supersonic, collisionless regime relevant to astrophysical collisionless shocks. The flows were created by irradiating a pair of opposing plastic (CH) foils with 1.8 kJ, 2-ns laser pulses on the OMEGA EP laser system. Ultrafast laser-driven proton radiography was used to image the Weibel-generated electromagnetic fields. The experimental observations are in good agreement with the analytical theory of the Weibel instability and with particle-in-cell simulations.

  7. Jeans instability of rotating magnetized quantum plasma: Influence of radiation

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, H., E-mail: [Department of Physics, Mewar University, Chittorgarh (Raj.) India (India); Pensia, R. K. [Department of Physics, Govt. Girls College, Neemuch (M.P.) India (India)


    The effect of radiative heat-loss function and rotation on the Jeans instability of quantum plasma is investigated. The basic set of equations for this problem is constructed by considering quantum magnetohydrodynamic (QMHD) model. Using normal mode analysis, the general dispersion relation is obtained. This dispersion relation is studied in both, longitudinal and transverse direction of propagations. In both case of longitudinal and transverse direction of propagation, the Jeans instability criterion is modified due to presence of radiative heat-loss function and quantum correction.

  8. Experimental investigation of a plane wall jet subjected to an external lateral flow (United States)

    Kaffel, Ahmed; Moureh, Jean; Harion, Jean-Luc; Russeil, Serge


    The present work aims to experimentally investigate the aerodynamic behavior of a wall jet subjected to external lateral stream by means of time-resolved PIV measurement technique. The experiments are performed on a reduced-scale model representing a generic configuration of a refrigerated display cabinet by focusing on the near-field region ( x/ e < 10) where strong interactions are expected between the jet core, wall boundary and external lateral stream. Comparisons of experimental data obtained with and without external perturbation make it possible to quantify the effect of the perturbation on the time-averaged wall jet characteristics such as airflow patterns, velocity profiles, maximum velocity decay, half-width jet growth, jet entrainment, RMS velocities and coherent structures as well as those related to the development of instabilities. Temporal PIV visualizations have allowed gaining insight on the effect of external lateral perturbation at the outer edge of the jet on the topology of Kelvin-Helmholtz vortices that dominate the early stages of wall jet transition process and play a relevant role on the jet entrainment inwards. Special attention was paid to bring new knowledge of the flow physics related to mutual interactions between outer and inner layer of the wall jet after the break-up of vortex filaments in the braid region due to the external perturbation.

  9. Stringy bounces and gradient instabilities

    CERN Document Server

    Giovannini, Massimo


    Bouncing solutions are obtained from a generally covariant action characterized by a potential which is a nonlocal functional of the dilaton field at two separated space-time points. Gradient instabilities are shown to arise in this context but they are argued to be nongeneric. After performing a gauge-invariant and frame-invariant derivation of the evolution equations of the fluctuations, a heuristic criterium for the avoidance of pathological instabilities is proposed and corroborated by a number of explicit examples that turn out to be compatible with a quasi-flat spectrum of curvature inhomogeneities for typical wavelengths larger than the Hubble radius.

  10. Research on aviation fuel instability (United States)

    Baker, C. E.; Bittker, D. A.; Cohen, S. M.; Seng, G. T.


    The problems associated with aircraft fuel instability are discussed. What is currently known about the problem is reviewed and a research program to identify those areas where more research is needed is discussed. The term fuel instability generally refers to the gums, sediments, or deposits which can form as a result of a set of complex chemical reactions when a fuel is stored for a long period at ambient conditions or when the fuel is thermally stressed inside the fuel system of an aircraft.

  11. Mechanical Instabilities of Biological Tubes (United States)

    Hannezo, Edouard; Prost, Jacques; Joanny, Jean-François


    We study theoretically the morphologies of biological tubes affected by various pathologies. When epithelial cells grow, the negative tension produced by their division provokes a buckling instability. Several shapes are investigated: varicose, dilated, sinuous, or sausagelike. They are all found in pathologies of tracheal, renal tubes, or arteries. The final shape depends crucially on the mechanical parameters of the tissues: Young’s modulus, wall-to-lumen ratio, homeostatic pressure. We argue that since tissues must be in quasistatic mechanical equilibrium, abnormal shapes convey information as to what causes the pathology. We calculate a phase diagram of tubular instabilities which could be a helpful guide for investigating the underlying genetic regulation.

  12. Hydromagnetic Instabilities in Neutron Stars

    CERN Document Server

    Lasky, Paul D; Kokkotas, Kostas D; Glampedakis, Kostas


    We model the non-linear ideal magnetohydrodynamics of poloidal magnetic fields in neutron stars in general relativity assuming a polytropic equation of state. We identify familiar hydromagnetic modes, in particular the 'sausage/varicose' mode and 'kink' instability inherent to poloidal magnetic fields. The evolution is dominated by the kink instability, which causes a cataclysmic reconfiguration of the magnetic field. The system subsequently evolves to new, non-axisymmetric, quasi-equilibrium end-states. The existence of this branch of stable quasi-equilibria may have consequences for magnetar physics, including flare generation mechanisms and interpretations of quasi-periodic oscillations.

  13. Political instability and illegal immigration. (United States)

    Campos, J E; Lien, D


    "Economic theory suggests that transnational migration results from the push-pull effect of wage differentials between host and source countries. In this paper, we argue that political instability exacerbates the migration flow, with greater instability leading to relatively larger flows. We conclude then that an optimal solution to the illegal immigration problem requires proper coordination of immigration and foreign policies by the host country. A narrow preoccupation with tougher immigration laws is wasteful and may be marginally effective." Emphasis is on the United States as a host country.

  14. Undulation Instability of Epithelial Tissues

    CERN Document Server

    Basan, Markus; Prost, Jacques; Risler, Thomas; 10.1103/PhysRevLett.106.158101


    Treating the epithelium as an incompressible fluid adjacent to a viscoelastic stroma, we find a novel hydrodynamic instability that leads to the formation of protrusions of the epithelium into the stroma. This instability is a candidate for epithelial fingering observed in vivo. It occurs for sufficiently large viscosity, cell-division rate and thickness of the dividing region in the epithelium. Our work provides physical insight into a potential mechanism by which interfaces between epithelia and stromas undulate, and potentially by which tissue dysplasia leads to cancerous invasion.

  15. Secondary instabilities of linearly heated falling films

    Institute of Scientific and Technical Information of China (English)

    HU Jun; SUN Dejun; HU Guohui; YIN Xieyuan


    Secondary instabilities of linearly heated failing films are studied through three steps. Firstly, the analysis of the primary linear instability on Miladinova's long wave equation of the linearly heated film is performed. Secondly, the similar Landau equation is derived through weak nonlinear theory, and a two-dimensional nonlinear saturation solution of primary instability is obtained within the weak nonlinear domain. Thirdly, the secondary (three-dimensional) instability of the two-dimensional wave is studied by the Floquet theorem.Our secondary instability analysis shows that the Marangoni number has destabilization effect on the secondary instability.

  16. Vortices in stratified protoplanetary disks : from baroclinic instability to vortex layers

    CERN Document Server

    Richard, S; Dizes, S Le


    Large scale vortices could play a key role in the evolution of protoplanetary disks, particularly in the dead-zone where no turbulence associated with magnetic field is expected. Their possible formation by the subcritical baroclinic instability is a complex issue due to the vertical structure of the disk and to the elliptical instability.} {In two-dimensional disks the baroclinic instability is studied as a function of the thermal transfer efficiency. In three-dimensional disks we explore the importance of radial and vertical stratification on the processes of vortex formation and amplification.} {Numerical simulations are performed using a fully compressible hydrodynamical code based on a second order finite volume method. We assume a perfect gas law in inviscid disk models in which heat transfer is due to either relaxation or diffusion.} {In 2D, the baroclinic instability with thermal relaxation leads to the formation of large-scale vortices, which are unstable with respect to the elliptic instability. In ...

  17. Nonlinear Farley-Buneman instability with Dust Impurities. (United States)

    Atamaniuk, B.; Volokitin, A. S.


    The regimes of nonlinear stabilization of instability of low frequency waves in magnetized, weakly ionized and inhomogeneous ionospheric dusty plasma are considered. In the lower ionosphere in the E--region, a complex process transforms wind energy into currents creating the E--region electrojet. If these currents exceed a certain critical amplitude, a streaming instability called the Farley--Buneman or a collisional two-stream instability develops. When the number of cooperating waves remains small due to a competition of processes of their instability and attenuation, the turbulence appears in the result of their stochastic behavior. Then even system with finite number of interacting waves can realize a turbulent state in active media. At conditions when electrons are magnetized and characteristic time of density oscillations exceed the rate of electron ion collisions and electron dust collision the drift of electrons perpendicular to magnetic field is the main motion. Consequently, the main nonlinearity appears in result of convection of a density perturbation in one wave by another wave in the perpendicular to magnetic field and mathematically is expressed in a specific vector form The strong collisional damping of waves allow to assume that a typical perturbed state of plasma can be described as finite set of interacting waves. This allow to avoid difficulties of 3D simulations and to make full study of nonlinear stabilization and influence of the dust component in the conditions when the number of interacting waves keeps small by the strong competition of processes wave damping and instabilities Keywords: Dusty Plasmas, Farley-Buneman Instability, Nonlinear Stabilization. REFERENCES 1. M. Oppenheim and N. Otani, Geophysical Research Letters, 22, pp. 353-356, 1995. 2. A.V. Volosevich and C.V. Meister, Int. Journal of Geomagnetism and aeronomy, 3 pp.151-156, 2002 3. A. S. Volokitin and B. Atamaniuk, Reduced nonlinear description of Farley-Buneman instability

  18. Instability of subharmonic resonances in magnetogravity shear waves. (United States)

    Salhi, A; Nasraoui, S


    We study analytically the instability of the subharmonic resonances in magnetogravity waves excited by a (vertical) time-periodic shear for an inviscid and nondiffusive unbounded conducting fluid. Due to the fact that the magnetic potential induction is a Lagrangian invariant for magnetohydrodynamic Euler-Boussinesq equations, we show that plane-wave disturbances are governed by a four-dimensional Floquet system in which appears, among others, the parameter ɛ representing the ratio of the periodic shear amplitude to the vertical Brunt-Väisälä frequency N(3). For sufficiently small ɛ and when the magnetic field is horizontal, we perform an asymptotic analysis of the Floquet system following the method of Lebovitz and Zweibel [Astrophys. J. 609, 301 (2004)]. We determine the width and the maximal growth rate of the instability bands associated with subharmonic resonances. We show that the instability of subharmonic resonance occurring in gravity shear waves has a maximal growth rate of the form Δ(m)=(3√[3]/16)ɛ. This instability persists in the presence of magnetic fields, but its growth rate decreases as the magnetic strength increases. We also find a second instability involving a mixing of hydrodynamic and magnetic modes that occurs for all magnetic field strengths. We also elucidate the similarity between the effect of a vertical magnetic field and the effect of a vertical Coriolis force on the gravity shear waves considering axisymmetric disturbances. For both cases, plane waves are governed by a Hill equation, and, when ɛ is sufficiently small, the subharmonic instability band is determined by a Mathieu equation. We find that, when the Coriolis parameter (or the magnetic strength) exceeds N(3)/2, the instability of the subharmonic resonance vanishes.

  19. Laterally loaded masonry

    DEFF Research Database (Denmark)

    Raun Gottfredsen, F.

    In this thesis results from experiments on mortar joints and masonry as well as methods of calculation of strength and deformation of laterally loaded masonry are presented. The strength and deformation capacity of mortar joints have been determined from experiments involving a constant compressive...... stress and increasing shear. The results show a transition to pure friction as the cohesion is gradually destroyed. An interface model of a mortar joint that can take into account this aspect has been developed. Laterally loaded masonry panels have also been tested and it is found to be characteristic...

  20. Lateral Thinking of Prospective Teachers (United States)

    Lawrence, A. S. Arul; Xavier, S. Amaladoss


    Edward de Bono who invented the term "lateral thinking" in 1967 is the pioneer of lateral thinking. Lateral thinking is concerned with the generation of new ideas. Liberation from old ideas and the stimulation of new ones are twin aspects of lateral thinking. Lateral thinking is a creative skills from which all people can benefit…

  1. Active control of magneto-hydrodynamic instabilities in hot plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Igochine, Valentin (ed.) [Max-Planck-Institut fuer Plasmaphysik, Garching (Germany)


    Written and edited by leading plasma physics researchers. Provides a toolkit for scientists and engineers aiming to optimize plasma performance. Comprehensive treatment of different plasma instabilities. During the past century, world-wide energy consumption has risen dramatically, which leads to a quest for new energy sources. Fusion of hydrogen atoms in hot plasmas is an attractive approach to solve the energy problem, with abundant fuel, inherent safety and no long-lived radioactivity. However, one of the limits on plasma performance is due to the various classes of magneto-hydrodynamic instabilities that may occur. The physics and control of these instabilities in modern magnetic confinement fusion devices is the subject of this book. Written by foremost experts, the contributions will provide valuable reference and up-to-date research reviews for ''old hands'' and newcomers alike.

  2. Cavity Evolution and Instability Constraints of Relativistic Interiors

    CERN Document Server

    Yousaf, Z


    In this manuscript, we have identified the dynamical instability constraints of a self-gravitating cylindrical object within the framework of $f(R,T)$ theory of gravity. We have explored the modified field equations and corresponding dynamical equations for the systematic constructions of our analysis. We have imposed the linear perturbations on metric and material variables with some known static profile up to first order in the perturbation parameter. The role of expansion scalar is also examined in this scenario. The instability regimes have been discussed in the background of Newtonian and post-Newtonian limits. We found that the dark source terms due to the influence of modification in the gravity model is responsible for the instability of the system.

  3. Cavity evolution and instability constraints of relativistic interiors

    Energy Technology Data Exchange (ETDEWEB)

    Yousaf, Z.; Bhatti, M.Z. ul Haq [University of the Punjab, Department of Mathematics, Lahore (Pakistan)


    In this manuscript, we have identified the dynamical instability constraints of a self-gravitating cylindrical object within the framework of the f(R, T) theory of gravity. We have explored the modified field equations and the corresponding dynamical equations for the systematic constructions of our analysis. We have imposed the linear perturbations on the metric and material variables with some known static profile up to first order in the perturbation parameter. The role of the expansion scalar is also examined in this scenario. The instability regimes have been discussed against the background of the Newtonian and post-Newtonian limits. We found that the dark source terms due to the influence of the modification in the gravity model is responsible for the instability of the system. (orig.)

  4. Rossby Wave Instability of Thin Accretion Disks - III. Nonlinear Simulations

    CERN Document Server

    Li, H; Wendroff, B; Liska, R


    (abridged) We study the nonlinear evolution of the Rossby wave instability in thin disks using global 2D hydrodynamic simulations. The key questions we are addressing in this paper are: (1) What happens when the instability becomes nonlinear? Specifically, does it lead to vortex formation? (2) What is the detailed behavior of a vortex? (3) Can the instability sustain itself and can the vortex last a long time? Among various initial equilibria that we have examined, we generally find that there are three stages of the disk evolution: (1) The exponential growth of the initial small amplitude perturbations. This is in excellent agreement with the linear theory; (2) The production of large scale vortices and their interactions with the background flow, including shocks. Significant accretion is observed due to these vortices. (3) The coupling of Rossby waves/vortices with global spiral waves, which facilitates further accretion throughout the whole disk. Even after more than 20 revolutions at the radius of vortic...

  5. Experimental study of parametric subharmonic instability for internal waves

    CERN Document Server

    Bourget, Baptiste; Joubaud, Sylvain; Odier, Philippe


    Internal waves are believed to be of primary importance as they affect ocean mixing and energy transport. Several processes can lead to the breaking of internal waves and they usually involve non linear interactions between waves. In this work, we study experimentally the parametric subharmonic instability (PSI), which provides an efficient mechanism to transfer energy from large to smaller scales. It corresponds to the destabilization of a primary plane wave and the spontaneous emission of two secondary waves, of lower frequencies and different wave vectors. Using a time-frequency analysis, we observe the time evolution of the secondary waves, thus measuring the growth rate of the instability. In addition, a Hilbert transform method allows the measurement of the different wave vectors. We compare these measurements with theoretical predictions, and study the dependence of the instability with primary wave frequency and amplitude, revealing a possible effect of the confinement due to the finite size of the be...

  6. Nonlinear vibration and rippling instability for embedded carbon nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Soltani, Payam; Mehdipour, I. [Islamic Azad University, Semnan (Iran, Islamic Republic of); Farshidianfar, A. [Ferdowsi University of Mashhad, Mashhad (Iran, Islamic Republic of); Ganji, D. D. [Babol University of Technology, Babol (Iran, Islamic Republic of)


    Based on the rippling deformations, a nonlinear continuum elastic model is developed to analyze the transverse vibration of single walled carbon nanotubes (SWCNTs) embedded on a Winkler elastic foundation. The nonlinear natural frequency has been derived analytically for typical boundary conditions using the perturbation method of multi-scales. The results indicate that the nonlinear resonant frequency due to the rippling is related to the stiffness of the foundation, the boundary conditions, the excitation load-to-damping ratio, and the diameter-to-length ratio. Moreover, the rippling instability of carbon nanotubes, as a structural instability, is introduced and the influences of several effective parameters on this kind of instability are widely discussed.

  7. Cavitation instabilities between fibres in a metal matrix composite

    DEFF Research Database (Denmark)

    Tvergaard, Viggo


    Short fibre reinforced metal matrix composites (MMC) are studied here to investigate the possibility that a cavitation instability can develop in the metal matrix. The high stress levels needed for a cavitation instability may occur in metal–ceramic systems due to the constraint on plastic flow...... of transversely staggered fibres is here modelled by using an axisymmetric cell model analysis. First the critical stress level is determined for a cavitation instability in an infinite solid made of the Al matrix material. By studying composites with different distributions and aspect ratios of the fibres...... induced by bonding to the ceramics that only show elastic deformation. In an MMC the stress state in the metal matrix is highly non-uniform, varying between regions where shear stresses are dominant and regions where hydrostatic tension is strong. An Al–SiC whisker composite with a periodic pattern...

  8. Estudo anatômico do ligamento patelofemoral lateral em joelho de cadáveres Anatomical study of the lateral patellofemoral ligament in cadaver knees

    Directory of Open Access Journals (Sweden)

    Marcelo Schmidt Navarro


    Full Text Available OBJETIVOS: Descrever o ligamento patelofemoral lateral (LPFL por meio de dissecação anatômica de joelhos de cadáveres frescos. Na literatura existe particular interesse pelo LPFL. Essa especial atenção é dada pela sua importância anatômica, biomecânica e pela necessidade da sua reconstrução nos casos de instabilidade medial da patela. MÉTODOS: O LPFL foi estudado em 20 joelhos de 20 cadáveres frescos por meio de dissecações anatômicas. As dissecações foram padronizadas e os dados anotados enviados para análise estatística. RESULTADOS: O LPFL apresentou em média 16,05mm de largura (desvio-padrão: 2,48, 42,10mm de comprimento (desvio-padrão: 8,84. Sua inserção femoral mostrou-se no epicôndilo femoral lateral e com expansão em forma de leque das suas fibras, predominantemente na região posterior e proximal ao epicôndilo lateral. Na patela a inserção encontrada foi na região súpero-lateral (na metade do terço superior no plano coronal, também com expansão das fibras, mas com menor intensidade. No plano sagital, o ligamento situava-se na metade posterior da borda da patela. O LPFL foi isolado na segunda camada retinacular lateral, o retináculo transverso profundo. CONCLUSÃO: O LPFL situa-se na camada retinacular transversa profunda, com a presença de uma expansão das suas fibras em forma de leque, tanto na inserção femoral quanto na patelar. No epicôndilo femoral a inserção encontra-se mais posterior e proximalmente e na patela está na metade posterior da borda patelar (plano sagital e no aspecto súpero-lateral.OBJECTIVES: To describe the lateral patellofemoral ligament (LPFL after anatomical dissection of fresh cadaver knees. The literature shows a particular interest for the LPFL. Such special attention is due to its anatomical and biomechanical importance, and also due to the need to reconstruct the ligament in the cases of medial patellar instability. METHODS: The LPFL was studied in 20 knees of 20

  9. Snow instability patterns at the scale of a small basin (United States)

    Reuter, Benjamin; Richter, Bettina; Schweizer, Jürg


    Spatial and temporal variations are inherent characteristics of the alpine snow cover. Spatial heterogeneity is supposed to control the avalanche release probability by either hindering extensive crack propagation or facilitating localized failure initiation. Though a link between spatial snow instability variations and meteorological forcing is anticipated, it has not been quantitatively shown yet. We recorded snow penetration resistance profiles with the snow micropenetrometer at an alpine field site during five field campaigns in Eastern Switzerland. For each of about 150 vertical profiles sampled per day a failure initiation criterion and the critical crack length were calculated. For both criteria we analyzed their spatial structure and predicted snow instability in the basin by external drift kriging. The regression models were based on terrain and snow depth data. Slope aspect was the most prominent driver, but significant covariates varied depending on the situation. Residual autocorrelation ranges were shorter than the ones of the terrain suggesting external influences possibly due to meteorological forcing. To explore the causes of the instability patterns we repeated the geostatistical analysis with snow cover model output as covariate data for one case. The observed variations of snow instability were related to variations in slab layer properties which were caused by preferential deposition of precipitation and differences in energy input at the snow surface during the formation period of the slab layers. Our results suggest that 3-D snow cover modeling allows reproducing some of the snow property variations related to snow instability, but in future work all relevant micrometeorological spatial interactions should be considered.

  10. Pair-Instability Supernovae of Fast Rotating Stars

    CERN Document Server

    Chen, Ke-Jung


    We present 2D simulations of pair-instability supernovae considering rapid rotation during their explosion phases. Recent studies of the Pop III star formation suggested that these stars could be born with a mass scale about 100 Msun and with a strong rotation. Based on stellar evolution models, these massive Pop III stars might have died as highly energetic pair-instability supernovae. We perform 2D calculations to investigate the impact of rotation on pair-instability supernovae. Our results suggest that rotation leads to an aspherical explosion due to an anisotropic collapse. If the first stars have a 50% of keplerian rotational rate of the oxygen core before their pair-instability explosions, the overall Ni production can be significantly reduced by about two orders of magnitude. An extreme case of 100% keplerian rotational rate shows an interesting feature of fluid instabilities along the equatorial plane caused by non-synchronized and non-isotropic ignitions of explosions, so that the shocks run into th...

  11. Frontal instability and the radiation of inertia gravity waves (United States)

    Flór, J.-B.; Scolan, H.


    In this experimental study we consider the instability of a density front in a differentially rotating two-layer fluid. Within the rotating frame the upper layer is accelerated by the differential rotation of a lid at the surface. In contrast to former comparable experiments of this type, we consider miscible fluids in a relatively wide annular tank. Velocity and dye measurements (PIV and LIF) allow for the measurements of the velocity and density fields. In the parameter space set by rotational Froude number and dissipation (i.e. ratio of spin-down time to disk rotation time), different flow regimes are observed, ranging from axisymmetric to irregular baroclinic instable flows. The different regimes more or less adjoin those found for immiscible fluids by Williams et al. (J. Fluid Mech. 2005). In the present experiments, we find a new type of instability that is due to the resonant interaction between Kelvin and Rossby waves (first studied Sakai, J. Fluid Mech 1989) and compare our experimental results with the analytical results obtained on an annular domain by Gula, Zeitlin and Plougonven (2009). Further, observations in the unstable flow regimes suggest 'spontaneous emission' of inertia gravity waves. The origin of these waves is discussed in the light of Kelvin-Helmholtz instability Hölmböe instability, and geostrophic adjustment waves.

  12. The Linear Instability of Dilute Ultrarelativistic e ± Pair Beams (United States)

    Chang, Philip; Broderick, Avery E.; Pfrommer, Christoph; Puchwein, Ewald; Lamberts, Astrid; Shalaby, Mohamad; Vasil, Geoffrey


    The annihilation of TeV photons from extragalactic TeV sources and the extragalactic background light produces ultrarelativistic {e}+/- beams, which are subject to powerful plasma instabilities that sap their kinetic energy. Here we study the linear phase of the plasma instabilities that these pair beams drive. To this end, we calculate the linear growth rate of the beam-plasma and oblique instability in the electrostatic approximation in both the reactive and kinetic regimes, assuming a Maxwell-Jüttner distribution for the pair beam. We reproduce the well-known reactive and kinetic growth rates for both the beam-plasma and oblique mode. We demonstrate for the oblique instability that there is a broad spectrum of unstable modes that grow at the maximum rate for a wide range of beam temperatures and wave-vector orientations relative to the beam. We also delineate the conditions for applicability for the reactive and kinetic regimes and find that the beam-plasma mode transitions to the reactive regime at a lower Lorentz factor than the oblique mode due to a combination of their different scalings and the anisotropy of the velocity dispersions. Applying these results to the ultrarelativistic {e}+/- beams from TeV blazars, we confirm that these beams are unstable to both the kinetic oblique mode and the reactive beam-plasma mode. These results are important in understanding how powerful plasma instabilities may sap the energy of the ultrarelativistic {e}+/- beams as they propagate through intergalactic space.

  13. Space-Charge Waves and Instabilities in Intense Beams (United States)

    Wang, J. G.


    Advancced accelerator applications, such as drivers for heavy ion inertial fusion, high-intensity synchrotrons for spallation neutron sources, high energy boosters, free electron lasers, high-power microwave generators, etc., require ever-increasing beam intensity. An important beam dynamics issue in such beams is the collective behavior of charged particles due to their space charge effects. This includes the phenomena of space-charge waves and instabilities excited on beams by external perturbations. It is very crucial to fully understand these phenomena in order to develop advanced accelerators for various applications. At the University of Maryland we have been conducting experimental programs to study space-charge waves and longitudinal instabilities by employing low-energy, high-current, space-charge dominated electron beams. Localized perturbations on the beams are generated from a gridded electron gun. In a conducting transport channel focused by short solenoids, these perturbations evolve into space-charge waves propagating on the beams. The wave speed is measured and many beam parameters are determined with this technique. The reflection of space-charge waves at the shoulder of an initially rectangular beam bunch is also observed. In a resistive-wall channel focused by a uniform long solenoid, the space-charge waves suffer longitudinal instability. The properties of the instabilities are studied in detail in the long wavelength range. In this talk we review our experimental results on the waves and instabilities and compare with theory.

  14. Edge instabilities of topological superconductors (United States)

    Hofmann, Johannes S.; Assaad, Fakher F.; Schnyder, Andreas P.


    Nodal topological superconductors display zero-energy Majorana flat bands at generic edges. The flatness of these edge bands, which is protected by time-reversal and translation symmetry, gives rise to an extensive ground-state degeneracy. Therefore, even arbitrarily weak interactions lead to an instability of the flat-band edge states towards time-reversal and translation-symmetry-broken phases, which lift the ground-state degeneracy. We examine the instabilities of the flat-band edge states of dx y-wave superconductors by performing a mean-field analysis in the Majorana basis of the edge states. The leading instabilities are Majorana mass terms, which correspond to coherent superpositions of particle-particle and particle-hole channels in the fermionic language. We find that attractive interactions induce three different mass terms. One is a coherent superposition of imaginary s -wave pairing and current order, and another combines a charge-density-wave and finite-momentum singlet pairing. Repulsive interactions, on the other hand, lead to ferromagnetism together with spin-triplet pairing at the edge. Our quantum Monte Carlo simulations confirm these findings and demonstrate that these instabilities occur even in the presence of strong quantum fluctuations. We discuss the implications of our results for experiments on cuprate high-temperature superconductors.

  15. Lending sociodynamics and economic instability (United States)

    Hawkins, Raymond J.


    We show how the dynamics of economic instability and financial crises articulated by Keynes in the General Theory and developed by Minsky as the Financial Instability Hypothesis can be formalized using Weidlich’s sociodynamics of opinion formation. The model addresses both the lending sentiment of a lender in isolation as well as the impact on that lending sentiment of the behavior of other lenders. The risk associated with lending is incorporated through a stochastic treatment of loan dynamics that treats prepayment and default as competing risks. With this model we are able to generate endogenously the rapid changes in lending opinion that attend slow changes in lending profitability and find these dynamics to be consistent with the rise and collapse of the non-Agency mortgage-backed securities market in 2007/2008. As the parameters of this model correspond to well-known phenomena in cognitive and social psychology, we can both explain why economic instability has proved robust to advances in risk measurement and suggest how policy for reducing economic instability might be formulated in an experimentally sound manner.

  16. The Chemistry of Beer Instability (United States)

    Stewart, Graham G.


    Brewing of beer, one of the oldest biotechnology industries was one of the earliest processes to be undertaken on commercial basis. Biological instability involves contamination of bacteria, yeast, or mycelia fungi and there is always a risk in brewing that beer can become contaminated by micro-organisms.

  17. Size effects on cavitation instabilities

    DEFF Research Database (Denmark)

    Niordson, Christian Frithiof; Tvergaard, Viggo


    In metal-ceramic systems the constraint on plastic flow leads to so high stress triaxialities that cavitation instabilities may occur. If the void radius is on the order of magnitude of a characteristic length for the metal, the rate of void growth is reduced, and the possibility of unstable cavi...... as the void grows to a size well above the characteristic material length....

  18. Waves and instabilities in plasmas

    CERN Document Server

    Chen Liu


    The topics covered in these notes are selective and tend to emphasize more on kinetic-theory approaches to waves and instabilities in both uniform and non-uniform plasmas, students are assumed to have some basic knowledge of plasma dynamics in terms of single-particle and fluid descriptions.


    Institute of Scientific and Technical Information of China (English)

    赵旻; 伍欣星; 邱小萍; 李晖; 戴天力; 谭云


    Objective: The role of human papillomavirus (HPV) in the development of cervical carcinoma has been clearly established but other factors could be involved in cervical tumorigenesis such as loss of heterozygosity (LOH) and microsatellite instability (MI). The aim of the present study was to investigate the genetic instability in cervical carcinoma tissues and provide evidence for discoveringnew tumor suppressor genes and screening diagnostic molecular marker of cervical carcinoma. Methods: Fifty primary cervical carcinoma samples from high-incidence area were analyzed by PCR for HPV16 infection, LOH and microsatellite instability. Results: HPV16 was detected in 88% of the cases. Sixty-six percent of total cases showed LOH with no more than 3 different loci per case. The highest frequency of the allelic loss was found in D18S474 (18q21, 40.5%). MI was detected in 4 cases (8%) only. Conclusion: Different percentages of LOH on specific chromosomal regions were found and MI was very infrequent in cervical carcinoma. The putative suppressor gene(s) could be located on specific chromosome regions such as 18q, and genetic instability could be involved in cervical tumorigenesis.

  20. Onset dominance in lateralization. (United States)

    Freyman, R L; Zurek, P M; Balakrishnan, U; Chiang, Y C


    Saberi and Perrott [Acustica 81, 272-275 (1995)] found that the in-head lateralization of a relatively long-duration pulse train could be controlled by the interaural delay of the single pulse pair that occurs at onset. The present study examined this further, using an acoustic pointer measure of lateralization, with stimulus manipulations designed to determine conditions under which lateralization was consistent with the interaural onset delay. The present stimuli were wideband pulse trains, noise-burst trains, and inharmonic complexes, 250 ms in duration, chosen for the ease with which interaural delays and correlations of select temporal segments of the stimulus could be manipulated. The stimulus factors studied were the periodicity of the ongoing part of the signal as well as the multiplicity and ambiguity of interaural delays. The results, in general, showed that the interaural onset delay controlled lateralization when the steady state binaural cues were relatively weak, either because the spectral components were only sparsely distributed across frequency or because the interaural time delays were ambiguous. Onset dominance can be disrupted by sudden stimulus changes within the train, and several examples of such changes are described. Individual subjects showed strong left-right asymmetries in onset effectiveness. The results have implications for understanding how onset and ongoing interaural delay cues contribute to the location estimates formed by the binaural auditory system.

  1. Laterality and reproductive indices. (United States)

    Kalichman, Leonid; Kobyliansky, Eugene


    Several previous studies support the association between manual dominance and age at menarche or age at menopause. The aim of the present study was to estimate the association between indices of laterality and reproductive indices. The studied sample comprised 650 Chuvashian women aged 18 to 80 years (mean, 46.9; SD = 16.2). The independent-sample t test was used to compare the age at menarche or age at menopause between individuals with right or left dominance of handedness, dominant eye, hand clasping, and arm folding. No significant differences in age at menarche or age at menopause between women with right and left dominance in any of the studied laterality indices were found. This is the first study that simultaneously evaluates the association between dominance in four laterality indices (handedness, dominant eye, hand clasping, and arm folding) and two reproductive indices (age at menarche and age at menopause). Result of our study do not support the hypothesis of a possible association between handedness (and other indices of laterality) and an early age at menarche or age at natural menopause.

  2. Measurements of entropy-layer instabilities over cone-ogive-cylinders at Mach 6 (United States)

    Greenwood, Roger T.

    Predicting the onset of boundary layer transition is critical in hypersonic flight. To improve transition prediction methods, it is necessary to understand the underlying instability mechanisms that cause transition. Entropy-layer instabilities are of particular interest in the design of blunt reentry vehicles and other blunt supersonic and hypersonic vehicles. Entropy-layer instabilities from outside the boundary layer may enter the boundary layer and have a significant effect on transition. There is little experimental data for entropy-layer instabilities. Experimental measurements of what appear to be entropy-layer instabilities have been made in the Boeing/AFOSR Mach-6 Quiet Tunnel (BAM6QT) using surface pressure transducers and hot-wire anemometry. A long cone-ogive-cylinder model with interchangeable cone-ogive noses was used to generate the shock curvature that resulted in an entropy layer conducive to instability growth. The nosetip angles of the cone-ogive range from 25 to 40 degrees, with a majority of the measurements taken with the sharp 30 to 35-degree nosetips. Surface measurements of the entropy-layer instabilities using the 30 to 35-degree configurations show disturbances between 15 and 50 kHz. As the nosetip angle increases, the frequency of the instability decreases slightly. Results also show that the instability magnitude as measured on the model surface increases with downstream distance, then decreases, before starting to increase again. The decrease is likely due to stabilization that occurs during the entropy-layer swallowing process. Off-surface measurements using hot wires have also been made for each of the cone-ogive-cylinder configurations. These measurements show the location, frequency, and relative magnitude of the entropy-layer instability. As the instability progresses downstream, it grows inside the entropy layer, then at a certain distance downstream, the instability approaches the model surface and enters the boundary layer

  3. Validation of an Adaptive Combustion Instability Control Method for Gas-Turbine Engines (United States)

    Kopasakis, George; DeLaat, John C.; Chang, Clarence T.


    This paper describes ongoing testing of an adaptive control method to suppress high frequency thermo-acoustic instabilities like those found in lean-burning, low emission combustors that are being developed for future aircraft gas turbine engines. The method called Adaptive Sliding Phasor Averaged Control, was previously tested in an experimental rig designed to simulate a combustor with an instability of about 530 Hz. Results published earlier, and briefly presented here, demonstrated that this method was effective in suppressing the instability. Because this test rig did not exhibit a well pronounced instability, a question remained regarding the effectiveness of the control methodology when applied to a more coherent instability. To answer this question, a modified combustor rig was assembled at the NASA Glenn Research Center in Cleveland, Ohio. The modified rig exhibited a more coherent, higher amplitude instability, but at a lower frequency of about 315 Hz. Test results show that this control method successfully reduced the instability pressure of the lower frequency test rig. In addition, due to a certain phenomena discovered and reported earlier, the so called Intra-Harmonic Coupling, a dramatic suppression of the instability was achieved by focusing control on the second harmonic of the instability. These results and their implications are discussed, as well as a hypothesis describing the mechanism of intra-harmonic coupling.

  4. Singlet and triplet instability theorems (United States)

    Yamada, Tomonori; Hirata, So


    A useful definition of orbital degeneracy—form-degeneracy—is introduced, which is distinct from the usual energy-degeneracy: Two canonical spatial orbitals are form-degenerate when the energy expectation value in the restricted Hartree-Fock (RHF) wave function is unaltered upon a two-electron excitation from one of these orbitals to the other. Form-degenerate orbitals tend to have isomorphic electron densities and occur in the highest-occupied and lowest-unoccupied molecular orbitals (HOMOs and LUMOs) of strongly correlated systems. Here, we present a mathematical proof of the existence of a triplet instability in a real or complex RHF wave function of a finite system in the space of real or complex unrestricted Hartree-Fock wave functions when HOMO and LUMO are energy- or form-degenerate. We also show that a singlet instability always exists in a real RHF wave function of a finite system in the space of complex RHF wave functions, when HOMO and LUMO are form-degenerate, but have nonidentical electron densities, or are energy-degenerate. These theorems provide Hartree-Fock-theory-based explanations of Hund's rule, a singlet instability in Jahn-Teller systems, biradicaloid electronic structures, and a triplet instability during some covalent bond breaking. They also suggest (but not guarantee) the spontaneous formation of a spin density wave (SDW) in a metallic solid. The stability theory underlying these theorems extended to a continuous orbital-energy spectrum proves the existence of an oscillating (nonspiral) SDW instability in one- and three-dimensional homogeneous electron gases, but only at low densities or for strong interactions.

  5. Genomic instability in newborn with short telomeres.

    Directory of Open Access Journals (Sweden)

    Jennifer Moreno-Palomo

    Full Text Available Telomere length is considered to be a risk factor in adults due to its proved association with cancer incidence and mortality. Since newborn present a wide interindividual variation in mean telomere length, it is relevant to demonstrate if these differences in length can act also as an early risk indicator. To answer this question, we have measured the mean telomere length of 74 samples of cord blood from newborns and studied its association with the basal genetic damage, measured as the frequency of binucleated cells carrying micronuclei. In addition, we have challenged the cells of a subgroup of individuals (N = 35 against mitomycin-C (MMC to establish their sensitivity to induced genomic instability. Results indicate that newborn with shorter telomeres present significantly higher levels of genetic damage when compared to those with longer telomeres. In addition, the cellular response to MMC was also significantly higher among those samples from subjects with shorter telomeres. Independently of the causal mechanisms involved, our results show for the first time that telomere length at delivery influence both the basal and induced genetic damage of the individual.Individuals born with shorter telomeres may be at increased risk, especially for those biological processes triggered by genomic instability as is the case of cancer and other age-related diseases.

  6. Symmetric instability in the Gulf Stream (United States)

    Thomas, Leif N.; Taylor, John R.; Ferrari, Raffaele; Joyce, Terrence M.


    Analyses of wintertime surveys of the Gulf Stream (GS) conducted as part of the CLIvar MOde water Dynamic Experiment (CLIMODE) reveal that water with negative potential vorticity (PV) is commonly found within the surface boundary layer (SBL) of the current. The lowest values of PV are found within the North Wall of the GS on the isopycnal layer occupied by Eighteen Degree Water, suggesting that processes within the GS may contribute to the formation of this low-PV water mass. In spite of large heat loss, the generation of negative PV was primarily attributable to cross-front advection of dense water over light by Ekman flow driven by winds with a down-front component. Beneath a critical depth, the SBL was stably stratified yet the PV remained negative due to the strong baroclinicity of the current, suggesting that the flow was symmetrically unstable. A large eddy simulation configured with forcing and flow parameters based on the observations confirms that the observed structure of the SBL is consistent with the dynamics of symmetric instability (SI) forced by wind and surface cooling. The simulation shows that both strong turbulence and vertical gradients in density, momentum, and tracers coexist in the SBL of symmetrically unstable fronts. SI is a shear instability that draws its energy from geostrophic flows. A parameterization for the rate of kinetic energy (KE) extraction by SI applied to the observations suggests that SI could result in a net dissipation of 33 mW m-2 and 1 mW m-2 for surveys with strong and weak fronts, respectively. The surveys also showed signs of baroclinic instability (BCI) in the SBL, namely thermally direct vertical circulations that advect biomass and PV. The vertical circulation was inferred using the omega equation and used to estimate the rate of release of available potential energy (APE) by BCI. The rate of APE release was found to be comparable in magnitude to the net dissipation associated with SI. This result points to an

  7. Lateral patellar retinacular release: changes over the last ten years. (United States)

    Fonseca, Leonardo Pini Rosalem Marciano da; Kawatake, Ednei Haruo; Pochini, Alberto de Castro


    Lateral retinacular release is a useful resource in knee surgery that can be used for disorders of the extensor mechanism. For many years, it was indiscriminately used in the treatment of the various patellofemoral joint alterations, with conflicting functional results. This study aimed to analyze the changes that have occurred in the indications and clinical effectiveness of lateral retinacular release by reviewing the relevant literature of the past ten years, comparing it to the classic literature on the subject. It was found that less extensive releases decompress the lateral patellar facet, helping with pain control, while decreasing the risks of medial subluxation. Nowadays, there is clear evidence for its indication in the lateral patellar hypercompression syndrome associated with anterior knee pain, as long as there is no related instability; furthermore, it will normally play an adjuvant role in extensor mechanism alignment surgeries for cases of recurrent patellar instability. The initial results for symptomatic patellofemoral osteoarthritis are promising when lateral release is combined with cartilage debridement; in total knee replacement, it is more commonly used for the correction of valgus deformity in order to improve the components' congruency. Finally, distinguishing the different patellofemoral joint pathologies is seen as crucial in order to indicate this procedure. Further randomized control trials that compare surgical techniques with long-term results are still needed.

  8. Observation of Parametric Instability in Advanced LIGO

    CERN Document Server

    Evans, Matthew; Fritschel, Peter; Miller, John; Barsotti, Lisa; Martynov, Denis; Brooks, Aidan; Coyne, Dennis; Abbott, Rich; Adhikari, Rana; Arai, Koji; Bork, Rolf; Kells, Bill; Rollins, Jameson; Smith-Lefebvre, Nicolas; Vajente, Gabriele; Yamamoto, Hiroaki; Derosa, Ryan; Effler, Anamaria; Kokeyama, Keiko; Betzweiser, Joseph; Frolov, Valera; Mullavey, Adam; O`Reilly, Brian; Dwyer, Sheila; Izumi, Kiwamu; Kawabe, Keita; Landry, Michael; Sigg, Daniel; Ballmer, Stefan; Massinger, Thomas J; Staley, Alexa; Mueller, Chris; Grote, Hartmut; Ward, Robert; King, Eleanor; Blair, David; Ju, Li; Zhao, Chunnong


    Parametric instabilities have long been studied as a potentially limiting effect in high-power interferometric gravitational wave detectors. Until now, however, these instabilities have never been observed in a kilometer-scale interferometer. In this work we describe the first observation of parametric instability in an Advanced LIGO detector, and the means by which it has been removed as a barrier to progress.

  9. Analogy between thermal convective and magnetohydrodynamic instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Valdmanis, Ya.Ya.; Kukainis, O.A.


    An examination is made of the analogy between thermo-convective instability and instability produced by various electromagnetic forces both in steady and alternating thermal and electromagnetic fields. An example is given for calculating an assumed bubble instability which could occur in an alternating magnetic field. 17 references.

  10. Amplitude Equation for Instabilities Driven at Deformable Surfaces - Rosensweig Instability (United States)

    Pleiner, Harald; Bohlius, Stefan; Brand, Helmut R.


    The derivation of amplitude equations from basic hydro-, magneto-, or electrodynamic equations requires the knowledge of the set of adjoint linear eigenvectors. This poses a particular problem for the case of a free and deformable surface, where the adjoint boundary conditions are generally non-trivial. In addition, when the driving force acts on the system via the deformable surface, not only Fredholm's alternative in the bulk, but also the proper boundary conditions are required to get amplitude equations. This is explained and demonstrated for the normal field (or Rosensweig) instability in ferrofluids as well as in ferrogels. An important aspect of the problem is its intrinsic dynamic nature, although at the end the instability is stationary. The resulting amplitude equation contains cubic and quadratic nonlinearities as well as first and (in the gel case) second order time derivatives. Spatial variations of the amplitudes cannot be obtained by using simply Newell's method in the bulk.

  11. Experimental, Numerical and Analytical Studies of the MHD-driven plasma jet, instabilities and waves (United States)

    Zhai, Xiang

    This thesis describes a series of experimental, numerical, and analytical studies involving the Caltech magnetohydrodynamically (MHD)-driven plasma jet experiment. The plasma jet is created via a capacitor discharge that powers a magnetized coaxial planar electrodes system. The jet is collimated and accelerated by the MHD forces. We present three-dimensional ideal MHD finite-volume simulations of the plasma jet experiment using an astrophysical magnetic tower as the baseline model. A compact magnetic energy/helicity injection is exploited in the simulation analogous to both the experiment and to astrophysical situations. Detailed analysis provides a comprehensive description of the interplay of magnetic force, pressure, and flow effects. We delineate both the jet structure and the transition process that converts the injected magnetic energy to other forms. When the experimental jet is sufficiently long, it undergoes a global kink instability and then a secondary local Rayleigh-Taylor instability caused by lateral acceleration of the kink instability. We present an MHD theory of the Rayleigh-Taylor instability on the cylindrical surface of a plasma flux rope in the presence of a lateral external gravity. The Rayleigh-Taylor instability is found to couple to the classic current-driven instability, resulting in a new type of hybrid instability. The coupled instability, produced by combination of helical magnetic field, curvature of the cylindrical geometry, and lateral gravity, is fundamentally different from the classic magnetic Rayleigh-Taylor instability occurring at a two-dimensional planar interface. In the experiment, this instability cascade from macro-scale to micro-scale eventually leads to the failure of MHD. When the Rayleigh-Taylor instability becomes nonlinear, it compresses and pinches the plasma jet to a scale smaller than the ion skin depth and triggers a fast magnetic reconnection. We built a specially designed high-speed 3D magnetic probe and

  12. Lateral Attitude Change. (United States)

    Glaser, Tina; Dickel, Nina; Liersch, Benjamin; Rees, Jonas; Süssenbach, Philipp; Bohner, Gerd


    The authors propose a framework distinguishing two types of lateral attitude change (LAC): (a) generalization effects, where attitude change toward a focal object transfers to related objects, and (b) displacement effects, where only related attitudes change but the focal attitude does not change. They bring together examples of LAC from various domains of research, outline the conditions and underlying processes of each type of LAC, and develop a theoretical framework that enables researchers to study LAC more systematically in the future. Compared with established theories of attitude change, the LAC framework focuses on lateral instead of focal attitude change and encompasses both generalization and displacement. Novel predictions and designs for studying LAC are presented.

  13. Treatment of lateral epicondylitis. (United States)

    Johnson, Greg W; Cadwallader, Kara; Scheffel, Scot B; Epperly, Ted D


    Lateral epicondylitis is a common overuse syndrome of the extensor tendons of the forearm. It is sometimes called tennis elbow, although it can occur with many activities. The condition affects men and women equally and is more common in persons 40 years or older. Despite the prevalence of lateral epicondylitis and the numerous treatment strategies available, relatively few high-quality clinical trials support many of these treatment options; watchful waiting is a reasonable option. Topical nonsteroidal anti-inflammatory drugs, corticosteroid injections, ultrasonography, and iontophoresis with nonsteroidal anti-inflammatory drugs appear to provide short-term benefits. Use of an inelastic, nonarticular, proximal forearm strap (tennis elbow brace) may improve function during daily activities. Progressive resistance exercises may confer modest intermediate-term results. Evidence is mixed on oral nonsteroidal antiinflammatory drugs, mobilization, and acupuncture. Patients with refractory symptoms may benefit from surgical intervention. Extracorporeal shock wave therapy, laser treatment, and electromagnetic field therapy do not appear to be effective.

  14. [Lateral lumbar disk herniation]. (United States)

    Deburge, A; Barre, E; Guigui, P

    A retrospective study of 41 lateral discal hernias observed between 1984 and 1991 were studied among the 1080 discal hernias treated during this period. CT scan, performed in all cases, distinguished several different types of hernia: foramen hernias (26), extraforamen hernias (12), mixed forms (5) associated with canal component (11). Thirteen disco scans were required. Nucleolysis was performed in 24 patients (58%) and surgical treatment was the first intention choice in 17 (41%). Outcome, evaluated with a function score developed in the unit were good in the 17 surgery cases (100%). In the nucleolysis patients results were good or excellent in 13, average in 4, and poor in 7. Five of the nucleolysis failures were later operated leading to good results in 3, average in 1 and no change in 1. Indications for surgery are more frequent in this type of discal hernia and results in our surgical series were better than those for chemonucleolysis.

  15. First-Time Patellofemoral Dislocation: Risk Factors for Recurrent Instability. (United States)

    Lewallen, Laura; McIntosh, Amy; Dahm, Diane


    Patellofemoral instability is a complex problem, which can be difficult to manage. The purpose of this study was to describe the demographics of patients with a first-time patellofemoral dislocation, and identify risk factors for recurrent instability. This was a single institution, institutional review board-approved, retrospective review of >2,000 patients with a patellar dislocation between 1998 and 2010. Inclusion criteria are as follows: (1) no prior history of patellofemoral subluxation or dislocation of the affected knee; (2) X-rays within 4 weeks of the initial instability episode; and (3) a dislocated patella requiring reduction, or history/findings suggestive of acute patellar dislocation (effusion/hemarthrosis, tenderness along the medial parapatellar structures, and apprehension with lateral patellar translation). Clinical records and radiographs were reviewed. The Caton-Deschamps and Insall-Salvati indices were used to evaluate patella alta. Trochlear dysplasia was assessed using the Dejour classification system. Skeletal maturity was graded based on the distal femoral and proximal tibial physes, using one of the following categories: open, closing, or closed. Three hundred twenty-six knees (312 patients) met the aforementioned criteria. There were 145 females (46.5%) and 167 males (53.5%), with an average age of 19.6 years (range, 9-62 years). Thirty-five patients (10.7%) were treated with surgery after the initial dislocation. All others were initially managed nonoperatively. Of the 291 patients managed nonoperatively, 89 (30.6%) had recurrent instability, 44 (49.4%) of which eventually required surgery. Several risk factors for recurrent instability were identified, including younger age (p alta (p = 0.02), and trochlear dysplasia (p plan. The clinical tool shown in Fig. 4 may be especially useful.

  16. Studies of longitudinal instability with an electron beam (United States)

    This progress report covers the research on the 'Study of Longitudinal Instability with an Electron Beam' performed at the University of Maryland during the period from September 1, 1993 to February 28, 1994 of the two-year grant sponsored by the Department of Energy, under Grant No. DEFG02-92ER54178. This research is motivated by the issue of longitudinal instability in induction linacs as drivers for heavy ion inertial fusion. The Fusion Policy Advisory Committee (FPAC) in its final report to DOE (September 1990) identified longitudinal instability as a key physics problem that needs to be solved if an induction linac is to be developed into a successful HIF driver. The FPAC report also stated that 'in parallel' to the design and construction of ILSE 'enhanced theoretical and experimental efforts are required for an improved understanding of potentially serious longitudinal beam instability issues'. The experiment with electron beams in this area is a low-cost way to gain a thorough understanding of the instability and to test computer codes in collaboration with LBL, LLNL, and I. Haber at NRL. The last six months saw the transition of the research activities from phase 1 to phase 2. By the end of last September, the experiments on space-charge waves had been completed. This had fulfilled the first year's goal of this two-year grant. Though the completion of the experiments was one month later than that scheduled and the data analysis still continues up to now, the authors have done much more than was originally proposed.

  17. The lateral angle revisited

    DEFF Research Database (Denmark)

    Morgan, Jeannie; Lynnerup, Niels; Hoppa, R.D.


    measurements taken from computed tomography (CT) scans. Previous reports have observed that the lateral angle size in females is significantly larger than in males. The method was applied to an independent series of 77 postmortem CT scans (42 males, 35 females) to validate its accuracy and reliability...... method appears to be of minimal practical use in forensic anthropology and archeology. © 2013 American Academy of Forensic Sciences....

  18. Contributions of microtubule dynamic instability and rotational diffusion to kinetochore capture

    CERN Document Server

    Blackwell, Robert; Edelmaier, Christopher; Gergely, Zachary R; Flynn, Patrick J; Montes, Salvador; Crapo, Ammon; Doostan, Alireza; McIntosh, J Richard; Glaser, Matthew A; Betterton, Meredith D


    Microtubule dynamic instability allows search and capture of kinetochores during spindle formation, an important process for accurate chromosome segregation during cell division. Recent work has found that microtubule rotational diffusion about minus-end attachment points contributes to kinetochore capture in fission yeast, but the relative contributions of dynamic instability and rotational diffusion are not well understood. We have developed a biophysical model of kinetochore capture in small fission-yeast nuclei using hybrid Brownian dynamics/kinetic Monte Carlo simulation techniques. With this model, we have studied the importance of dynamic instability and microtubule rotational diffusion for kinetochore capture, both to the lateral surface of a microtubule and at or near its end. Over a range of biologically relevant parameters, microtubule rotational diffusion decreased capture time, but made a relatively small contribution compared to dynamic instability. At most, rotational diffusion reduced capture ...

  19. Explosive magnetorotational instability in Keplerian disks

    CERN Document Server

    Shtemler, Yu; Mond, M


    Differentially rotating disks under the effect of axial magnetic field are prone to a nonlinear explosive magnetorotational instability (EMRI). The dynamic equations that govern the temporal evolution of the amplitudes of three weakly-detuned resonantly interacting modes are derived. As distinct from exponential growth in the strict resonance triads EMRI occurs due to the resonant interactions of a MRI mode with stable Alfv\\'en-Coriolis and magnetosonic modes. Numerical solutions of the dynamic equations for amplitudes of a triad indicate that two types of perturbations behavior can be excited for resonance conditions: (i) EMRI which leads to infinite values of the three amplitudes within a finite time, and (ii) bounded irregular oscillations of all three amplitudes. Asymptotic explicit solutions of the dynamic equations are obtained for EMRI regimes and are shown to match the numerical solutions near the explosion time.

  20. Explosive magnetorotational instability in Keplerian disks (United States)

    Shtemler, Yu.; Liverts, E.; Mond, M.


    Differentially rotating disks under the effect of axial magnetic field are prone to a nonlinear explosive magnetorotational instability (EMRI). The dynamic equations that govern the temporal evolution of the amplitudes of three weakly detuned resonantly interacting modes are derived. As distinct from exponential growth in the strict resonance triads, EMRI occurs due to the resonant interactions of an MRI mode with stable Alfvén-Coriolis and magnetosonic modes. Numerical solutions of the dynamic equations for amplitudes of a triad indicate that two types of perturbations behavior can be excited for resonance conditions: (i) EMRI which leads to infinite values of the three amplitudes within a finite time, and (ii) bounded irregular oscillations of all three amplitudes. Asymptotic explicit solutions of the dynamic equations are obtained for EMRI regimes and are shown to match the numerical solutions near the explosion time.

  1. Suppression of Instability in Rotatory Hydromagnetic Convection

    Indian Academy of Sciences (India)

    Joginder S Dhiman


    Recently discovered hydrodynamic instability [1], in a simple Bénard configuration in the parameter regime 02 > 1 under the action of a nonadverse temperature gradient, is shown to be suppressed by the simultaneous action of a uniform rotation and a uniform magnetic field both acting parallel to gravity for oscillatory perturbations whenever $(\\mathscr{Q}_1/^2+\\mathscr{J}/^4) > 1$ and the effective Rayleigh number $\\mathcal{R}$(1-02) is dominated by either 274(1 + 1/1)/4 or 274/2 according as 1 ≥ 1 or 1 ≤ 1 respectively. Here 0 is the temperature of the lower boundary while 2 is the coefficient of specific heat at constant volume due to temperature variation and 1, $\\mathcal{R}, \\mathscr{Q}$ and $\\mathscr{T}$ respectively denote the magnetic Prandtl number, the Rayleigh number, the Chandrasekhar number and the Taylor number.

  2. Explosive magnetorotational instability in Keplerian disks

    Energy Technology Data Exchange (ETDEWEB)

    Shtemler, Yu., E-mail:; Liverts, E., E-mail:; Mond, M., E-mail: [Department of Mechanical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105 (Israel)


    Differentially rotating disks under the effect of axial magnetic field are prone to a nonlinear explosive magnetorotational instability (EMRI). The dynamic equations that govern the temporal evolution of the amplitudes of three weakly detuned resonantly interacting modes are derived. As distinct from exponential growth in the strict resonance triads, EMRI occurs due to the resonant interactions of an MRI mode with stable Alfvén–Coriolis and magnetosonic modes. Numerical solutions of the dynamic equations for amplitudes of a triad indicate that two types of perturbations behavior can be excited for resonance conditions: (i) EMRI which leads to infinite values of the three amplitudes within a finite time, and (ii) bounded irregular oscillations of all three amplitudes. Asymptotic explicit solutions of the dynamic equations are obtained for EMRI regimes and are shown to match the numerical solutions near the explosion time.

  3. One-hit wonders of genomic instability

    Directory of Open Access Journals (Sweden)

    Strunnikov Alexander V


    Full Text Available Abstract Recent data show that cells from many cancers exhibit massive chromosome instability. The traditional view is that the gradual accumulation of mutations in genes involved in transcriptional regulation and cell cycle controls results in tumor development. This, however, does not exclude the possibility that some mutations could be more potent than others in destabilizing the genome by targeting both chromosomal integrity and corresponding checkpoint mechanisms simultaneously. Three such examples of "single-hit" lesions potentially leading to heritable genome destabilization are discussed. They include: failure to release sister chromatid cohesion due to the incomplete proteolytic cleavage of cohesin; massive merotelic kinetochore misattachments upon condensin depletion; and chromosome under-replication. In all three cases, cells fail to detect potential chromosomal bridges before anaphase entry, indicating that there is a basic cell cycle requirement to maintain a degree of sister chromatid bridging that is not recognizable as chromosomal damage.

  4. Competing structural instabilities in cubic perovskites

    CERN Document Server

    Vanderbilt, D


    We study the antiferrodistortive instability and its interaction with ferroelectricity in cubic perovskite compounds. Our first-principles calculations show that coexistence of both instabilities is very common. We develop a first-principles scheme to study the thermodynamics of these compounds when both instabilities are present, and apply it to SrTiO$_3$. We find that increased pressure enhances the antiferrodistortive instability while suppressing the ferroelectric one. Moreover, the presence of one instability tends to suppress the other. A very rich $P$--$T$ phase diagram results.

  5. Nonlinear evolution of drift instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Lee, W.W.; Krommes, J.A.; Oberman, C.R.; Smith, R.A.


    The nonlinear evolution of collisionless drift instabilities in a shear-free magnetic field has been studied by means of gyrokinetic particle simulation as well as numerical integration of model mode-coupling equations. The purpose of the investigation is to identify relevant nonlinear mechanisms responsible for the steady-state drift wave fluctuations. It is found that the saturation of the instability is mainly caused by the nonlinear E x B convection of the resonant electrons and their associated velocity space nonlinearity. The latter also induces energy exchange between the competing modes, which, in turn, gives rise to enhanced diffusion. The nonlinear E x B convection of the ions, which contributes to the nonlinear frequency shift, is also an important ingredient for the saturation.

  6. Streaming Instabilities in Protoplanetary Disks

    CERN Document Server

    Youdin, A N; Youdin, Andrew N.; Goodman, Jeremy


    Interpenetrating streams of solids and gas in a Keplerian disk produce a local, linear instability. The two components mutually interact via aerodynamic drag, which generates radial drift and triggers unstable modes. The secular instability does not require self-gravity, yet it generates growing particle density perturbations that could seed planetesimal formation. Growth rates are slower than dynamical, but faster than radial drift, timescales. Growth rates, like streaming velocities, are maximized for marginal coupling (stopping times comparable dynamical times). Fastest growth occurs when the solid to gas density ratio is order unity and feedback is strongest. Curiously, growth is strongly suppressed when the densities are too nearly equal. The relation between background drift and wave properties is explained by analogy with Howard's semicircle theorem. The three-dimensional, two-fluid equations describe a sixth order (in the complex frequency) dispersion relation. A terminal velocity approximation allows...

  7. Instability of supersymmetric microstate geometries

    CERN Document Server

    Eperon, Felicity C; Santos, Jorge E


    We investigate the classical stability of supersymmetric, asymptotically flat, microstate geometries with five non-compact dimensions. Such geometries admit an "evanescent ergosurface": a timelike hypersurface of infinite redshift. On such a surface, there are null geodesics with zero energy relative to infinity. These geodesics are stably trapped in the potential well near the ergosurface. We present a heuristic argument indicating that this feature is likely to lead to a nonlinear instability of these solutions. We argue that the precursor of such an instability can be seen in the behaviour of linear perturbations: nonlinear stability would require that all linear perturbations decay sufficiently rapidly but the stable trapping implies that some linear perturbation decay very slowly. We study this in detail for the most symmetric microstate geometries. By constructing quasinormal modes of these geometries we show that generic linear perturbations decay slower than any inverse power of time.

  8. Buckling instability of squeezed droplets

    CERN Document Server

    Elfring, Gwynn J


    Motivated by recent experiments, we consider theoretically the compression of droplets pinned at the bottom on a surface of finite area. We show that if the droplet is sufficiently compressed at the top by a surface, it will always develop a shape instability at a critical compression. When the top surface is flat, the shape instability occurs precisely when the apparent contact angle of the droplet at the pinned surface is pi, regardless of the contact angle of the upper surface, reminiscent of past work on liquid bridges and sessile droplets as first observed by Plateau. After the critical compression, the droplet transitions from a symmetric to an asymmetric shape. The force required to deform the droplet peaks at the critical point then progressively decreases indicative of catastrophic buckling. We characterize the transition in droplet shape using illustrative examples in two dimensions followed by perturbative analysis as well as numerical simulation in three dimensions. When the upper surface is not f...

  9. Stretching Folding Instability and Nanoemulsions

    CERN Document Server

    Chan, Chon U


    Here we show a folding-stretching instability in a microfluidic flow focusing device using silicon oil (100cSt) and water. The fluid dynamics video demonstrates an oscillating thread of oil focused by two co-flowing streams of water. We show several high-speed sequences of these oscillations with 30,000 frames/s. Once the thread is decelerated in a slower moving pool downstream an instability sets in and water-in-oil droplets are formed. We reveal the details of the pinch-off with 500,000 frames/s. The pinch-off is so repeatable that complex droplet patterns emerge. Some of droplets are below the resolution limit, thus smaller than 1 micrometer in diameter.

  10. Instability of ties in compression

    DEFF Research Database (Denmark)

    Buch-Hansen, Thomas Cornelius


    Masonry cavity walls are loaded by wind pressure and vertical load from upper floors. These loads results in bending moments and compression forces in the ties connecting the outer and the inner wall in a cavity wall. Large cavity walls are furthermore loaded by differential movements from...... the temperature gradient between the outer and the inner wall, which results in critical increase of the bending moments in the ties. Since the ties are loaded by combined compression and moment forces, the loadbearing capacity is derived from instability equilibrium equations. Most of them are iterative, since......-connectors in cavity walls was developed. The method takes into account constraint conditions limiting the free length of the wall tie, and the instability in case of pure compression which gives an optimal load bearing capacity. The model is illustrated with examples from praxis....

  11. Instability of supersymmetric microstate geometries

    Energy Technology Data Exchange (ETDEWEB)

    Eperon, Felicity C.; Reall, Harvey S.; Santos, Jorge E. [Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA (United Kingdom)


    We investigate the classical stability of supersymmetric, asymptotically flat, microstate geometries with five non-compact dimensions. Such geometries admit an “evanescent ergosurface”: a timelike hypersurface of infinite redshift. On such a surface, there are null geodesics with zero energy relative to infinity. These geodesics are stably trapped in the potential well near the ergosurface. We present a heuristic argument indicating that this feature is likely to lead to a nonlinear instability of these solutions. We argue that the precursor of such an instability can be seen in the behaviour of linear perturbations: nonlinear stability would require that all linear perturbations decay sufficiently rapidly but the stable trapping implies that some linear perturbation decay very slowly. We study this in detail for the most symmetric microstate geometries. By constructing quasinormal modes of these geometries we show that generic linear perturbations decay slower than any inverse power of time.

  12. Modern management of patellar instability. (United States)

    Rhee, Shin-Jae; Pavlou, George; Oakley, Jeremy; Barlow, David; Haddad, Farres


    Recurrent patellofemoral instability is a disabling condition, attributed to a variety of anatomical aetiologies. Trochlear dysplasia, patella alta, an increased tibial tubercle trochlear groove distance of greater than 20 mm and soft tissue abnormalities such as a torn medial patellofemoral ligament and inadequate vastus medialis obliquus are all factors to be considered. Management of this condition remains difficult and controversial and knowledge of the functional anatomy and biomechanics of the patellofemoral joint, a detailed history and clinical examination, and an accurate patient assessment are all imperative to formulate an appropriate management plan. Surgical treatment is based on the underlying anatomical pathology with an aim to restore normal patellofemoral kinematics. We summarise aspects of assessment, treatment and outcome of patellofemoral instability and propose an algorithm of treatment.

  13. Mechanical Instabilities of Biological Tubes

    CERN Document Server

    Hannezo, Edouard; Prost, Jacques; 10.1103/PhysRevLett.109.018101


    We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability. Several shapes are investigated : varicose, enlarged, sinusoidal or sausage-like, all of which are found in pathologies of tracheal, renal tubes or arteries. The final shape depends crucially on the mechanical parameters of the tissues : Young modulus, wall-to-lumen ratio, homeostatic pressure. We argue that since tissues must be in quasistatic mechanical equilibrium, abnormal shapes convey information as to what causes the pathology. We calculate a phase diagram of tubular instabilities which could be a helpful guide for investigating the underlying genetic regulation.

  14. Circulation in blast driven instabilities (United States)

    Henry de Frahan, Marc; Johnsen, Eric


    Mixing in many natural phenomena (e.g. supernova collapse) and engineering applications (e.g. inertial confinement fusion) is often initiated through hydrodynamic instabilities. Explosions in these systems give rise to blast waves which can interact with perturbations at interfaces between different fluids. Blast waves are formed by a shock followed by a rarefaction. This wave profile leads to complex time histories of interface acceleration. In addition to the instabilities induced by the acceleration field, the rarefaction from the blast wave decompresses the material at the interface, further increasing the perturbation growth. After the passage of the wave, circulation circulation generated by the blast wave through baroclinic vorticity continues to act upon the interface. In this talk, we provide scaling laws for the circulation and amplitude growth induced by the blast wave. Numerical simulations of the multifluid Euler equations solved using a high-order accurate Discontinuous Galerkin method are used to validate the theoretical results.

  15. Direct lateral maneuvers in hawkmoths

    Directory of Open Access Journals (Sweden)

    Jeremy S. M. Greeter


    Full Text Available We used videography to investigate direct lateral maneuvers, i.e. ‘sideslips’, of the hawkmoth Manduca sexta. M. sexta sideslip by rolling their entire body and wings to reorient their net force vector. During sideslip they increase net aerodynamic force by flapping with greater amplitude, (in both wing elevation and sweep, allowing them to continue to support body weight while rolled. To execute the roll maneuver we observed in sideslips, they use an asymmetric wing stroke; increasing the pitch of the roll-contralateral wing pair, while decreasing that of the roll-ipsilateral pair. They also increase the wing sweep amplitude of, and decrease the elevation amplitude of, the contralateral wing pair relative to the ipsilateral pair. The roll maneuver unfolds in a stairstep manner, with orientation changing more during downstroke than upstroke. This is due to smaller upstroke wing pitch angle asymmetries as well as increased upstroke flapping counter-torque from left-right differences in global reference frame wing velocity about the moth's roll axis. Rolls are also opposed by stabilizing aerodynamic moments from lateral motion, such that rightward roll velocity will be opposed by rightward motion. Computational modeling using blade-element approaches confirm the plausibility of a causal linkage between the previously mentioned wing kinematics and roll/sideslip. Model results also predict high degrees of axial and lateral damping. On the time scale of whole and half wing strokes, left-right wing pair asymmetries directly relate to the first, but not second, derivative of roll. Collectively, these results strongly support a roll-based sideslip with a high degree of roll damping in M. sexta.

  16. MD 751: Train Instability Threshold

    CERN Document Server

    Carver, Lee Robert; Metral, Elias; Salvant, Benoit; Levens, Tom; Nisbet, David; Zobov, M; CERN. Geneva. ATS Department


    The purpose of this MD is to measure the octupole current thresholds for stability for a single bunch, and then make an immediate comparison (with the same operational settings) for a train of 72 bunches separated by 25ns. From theory, the expected thresholds should be similar. Any discrepancy between the two cases will be of great interest as it could indicate the presence of additional mechanisms that contribute to the instability threshold, for example electron cloud.

  17. Polygonal instabilities on interfacial vorticities

    CERN Document Server

    Labousse, Matthieu


    We report the results of a theoretical investigation of the stability of a toroidal vortex bound by an interface. Two distinct instability mechanisms are identified that rely on, respectively, surface tension and fluid inertia, either of which may prompt the transformation from a circular to a polygonal torus. Our results are discussed in the context of three experiments, a toroidal vortex ring, the hydraulic jump, and the hydraulic bump.

  18. Instability of colliding metastable strings

    Energy Technology Data Exchange (ETDEWEB)

    Hiramatsu, Takashi [Kyoto Univ. (Japan). Yukawa Inst. for Theoretical Physics; Eto, Minoru [Yamagata Univ. (Japan). Dept. of Physics; Kamada, Kohei [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Kobayashi, Tatsuo [Kyoto Univ. (Japan). Dept. of Physics; Ookouchi, Yutaka [Kyoto Univ. (Japan). Dept. of Physics; Kyoto Univ. (Japan). The Hakubi Center for Advanced Research


    We investigate the collision dynamics of two metastable strings which can be viewed as tube-like domain walls with winding numbers interpolating a false vacuum and a true vacuum. We find that depending on the relative angle and speed of two strings, instability of strings increases and the false vacuum is filled out by rapid expansion of the strings or of a remnant of the collision.

  19. Galeazzi semitendinosus tenodesis for patellofemoral instability in skeletally immature patients. (United States)

    Grannatt, Kathryn; Heyworth, Benton E; Ogunwole, Olabode; Micheli, Lyle J; Kocher, Mininder S


    Numerous surgical treatments have been described to address subluxation or dislocation of the patella, but many are not suitable for the skeletally immature patient, as they risk injury to the proximal tibial physis or tibial tubercle apophysis. The Galeazzi semitendinosus tenodesis is a soft-tissue reconstruction technique designed to stabilize the patella without altering the femoral or the bony structures about the knee. We sought to determine if this semitendinosus tenodesis is a safe and effective treatment for patellofemoral instability in skeletally immature patients. We retrospectively analyzed the records of a population of skeletally immature patients who underwent semitendinosus tenodesis for patellofemoral instability at our institution from 1990 to 2006. Condition-specific outcome and function were prospectively collected, including the International Knee Documentation Committee (IKDC) score, Kujala Score, and Marx Activity Scale. Recurrent instability was defined as patient-reported postoperative subluxation, dislocation, or both. Twenty-eight patients (34 total knees) were included in the study. Average follow-up was 70 months (range, 27 to 217 mo). Patients reported recurrent instability in 28 of the 34 knees (82%). Overall, 41% of patients had IKDC scores Galeazzi semitendinosus tenodesis is a safe procedure for patellofemoral instability in skeletally immature patients, but our long-term data suggest it may not be as successful as previously reported. Approximately 82% of patients experienced recurrent subluxation or dislocation despite surgical intervention, which may be due in large part to various predisposing factors, and there was a 35% rate of second surgeries. However, given the variability in techniques and reported results of patellofemoral stabilizing procedures in skeletally immature patients, the Galeazzi procedure may still be a reasonable way to temporize the difficult problem of patellar instability until patients reach skeletal

  20. Stabilization effect ofWeibel modes due to inverse bremsstrahlung absorption in laser fusion plasma using Krook collisions model

    Indian Academy of Sciences (India)



    In this work, the Weibel instability due to inverse bremsstrahlung absorption in laser fusion plasma has been investigated. The stabilization effect due to the coupling of the self-generated magnetic field by Weibel instability with the laser wave field is explicitly showed. The main result obtained in this work is that the inclusion of self-generated magnetic field due to Weibel instability to the inverse bremsstrahlung absorption causes a stabilizing effect of excited Weibel modes. We found a decrease in the spectral range of Weibel unstable modes.This decrease is accompanied by a reduction of two orders in the growth rate of instability or even stabilization of these modes. It has been shown that the previous analyses of the Weibel instability due to inverse bremsstrahlunghave overestimated the values of the generated magnetic fields. Therefore, the generation of magnetic fields by the Weibel instability due to inverse bremsstrahlung should not affect the experiences of an inertial confinement fusion.

  1. due to Capillary Forces

    Directory of Open Access Journals (Sweden)

    Hassen M. Ouakad


    Full Text Available We present modeling and analysis for the static behavior and collapse instabilities of doubly-clamped and cantilever microbeams subjected to capillary forces. These forces can be as a result of a volume of liquid trapped underneath the microbeam during the rinsing and drying process in fabrication. The model considers the microbeam as a continuous medium, the capillary force as a nonlinear function of displacement, and accounts for the mid-plane stretching and geometric nonlinearities. The capillary force is assumed to be distributed over a specific length underneath the microbeam. The Galerkin procedure is used to derive a reduced-order model consisting of a set of nonlinear algebraic and differential equations that describe the microbeams static and dynamic behaviors. We study the collapse instability, which brings the microbeam from its unstuck configuration to touch the substrate and gets stuck in the so-called pinned configuration. We calculate the pull-in length that distinguishes the free from the pinned configurations as a function of the beam thickness and gap width for both microbeams. Comparisons are made with analytical results reported in the literature based on the Ritz method for linear and nonlinear beam models. The instability problem, which brings the microbeam from a pinned to adhered configuration is also investigated. For this case, we use a shooting technique to solve the boundary-value problem governing the deflection of the microbeams. The critical microbeam length for this second instability is also calculated.

  2. Gravitational instabilities in astrophysical fluids (United States)

    Tohline, Joel E.


    Over the past decade, the significant advancements that have been made in the development of computational tools and numerical techniques have allowed astrophysicists to begin to model accurately the nonlinear growth of gravitational instabilities in a variety of physical systems. The fragmentation or rotationally driven fission of dynamically evolving, self-gravitating ``drops and bubbles'' is now routinely modeled in full three-dimensional generality as we attempt to understand the behavior of protostellar clouds, rotating stars, galaxies, and even the primordial soup that defined the birth of the universe. A brief review is presented here of the general insights that have been gained from studies of this type, followed by a somewhat more detailed description of work, currently underway, that is designed to explain the process of binary star formation. A short video animation sequence, developed in conjunction with some of the research being reviewed, illustrates the basic-nature of the fission instability in rotating stars and of an instability that can arise in a massive disk that forms in a protostellar cloud.

  3. Drift-Alfven instabilities of a finite beta plasma shear flow along a magnetic field (United States)

    Mikhailenko, V. V.; Mikhailenko, V. S.; Lee, Hae June


    It was derived that the drift-Alfven instabilities with the shear flow parallel to the magnetic field have significant difference from the drift-Alfven instabilities of a shearless plasma when the ion temperature is comparable with electron temperature for a finite plasma beta. The velocity shear not only modifies the frequency and the growth rate of the known drift-Alfven instability, which develops due to the inverse electron Landau damping, but also triggers a combined effect of the velocity shear and the inverse ion Landau damping, which manifests the development of the ion kinetic shear-flow-driven drift-Alfven instability. The excited unstable waves have the phase velocities along the magnetic field comparable with the ion thermal velocity, and the growth rate is comparable with the frequency. The development of this instability may be the efficient mechanism of the ion energization in shear flows.

  4. Collisional effects on the oblique instability in relativistic beam-plasma interactions (United States)

    Hao, B.; Ding, W. J.; Sheng, Z. M.; Ren, C.; Kong, X.; Mu, J.; Zhang, J.


    The general oblique instability for a relativistic electron beam propagating through a warm and resistive plasma is investigated fully kinetically by a variable rotation method. Analysis shows that the electrostatic part of the oblique instability is attenuated and eventually stabilized by collisional effects. However, the electromagnetic part of the oblique instability (EMOI) is enhanced. Since the current-filamentation instability as a special case of the EMOI has a larger growth rate, it becomes dominant in the collisional case as shown in our two-dimensional particle-in-cell simulations. While the beam diverges in the collisionless case, it can become magnetically collimated in the collisional case due to stabilization of the electrostatic instabilities when the initial beam spreading angle is less than certain magnitude such as a dozen degrees.

  5. Linear Instabilities Driven by Differential Rotation in Very Weakly Magnetized Plasmas

    CERN Document Server

    Quataert, Eliot; Spitkovsky, Anatoly


    We study the linear stability of weakly magnetized differentially rotating plasmas in both collisionless kinetic theory and Braginskii's theory of collisional, magnetized plasmas. We focus on the very weakly magnetized limit that is important for understanding how astrophysical magnetic fields originate and are amplified at high redshift. We show that the single instability of fluid theory - the magnetorotational instability mediated by magnetic tension - is replaced by two distinct instabilities, one associated with ions and one with electrons. Each of these has a different way of tapping into the free energy of differential rotation. The ion instability is driven by viscous transport of momentum across magnetic field lines due to a finite ion cyclotron frequency (gyroviscosity); the fastest growing modes have wavelengths significantly longer than MHD and Hall MHD predictions. The electron instability is a whistler mode driven unstable by the temperature anisotropy generated by differential rotation; the gro...

  6. Clinical measurement of mechanical ankle instability. (United States)

    Parasher, Raju K; Nagy, Dawn R; Em, April L; Phillips, Howard J; Mc Donough, Andrew L


    Clinicians commonly use the anterior draw test (ligament laxity) and distal fibular position (lateral malleolus displacement), to measure ankle instability. The purpose of this study was to establish intra-rater and inter-rater reliability for the anterior draw test and distal fibular position in a clinical setting. The anterior draw test (AD) was measured with a plastic Goniometer, and was defined as the linear displacement of the foot as it is drawn anteriorly with the ankle held in 20 degrees of plantar-flexion. Distal fibular position (DFP) was measured in standing using a digital vernier caliper and was the relative linear distance between the lateral and the medial malleoli. 20 participants aged 21-28 volunteered for the study and were measured on both ankles. It was found that Intra-tester reliability (ICC) ranged from 0.88 to 0.97 for AD and DFP; while inter-tester reliability (ICC) was 0.6 for AD and 0.77 for DFP. In addition for measures across trials, the standard error of the measurement (SEM) was, on average 0.66 mm for AD and 1.7 mm for DFP. While the limits of agreement (LOA) was ±0.17 mm for AD and ±4.03 mm for DFP. However, the SEM and LOA between testers was 2.27 mm and ±2.27 mm respectively for AD; and for 3.1 mm and ±10.4 mm for DFP. Overall the results suggest that both measures, as defined in this study exhibit moderate to good reliability and low standard error of measurement, suggesting a high degree of repeatability across trials.

  7. Piezoelectric control of structures prone to instabilities (United States)

    Kim, Sunjung

    Thin-walled structures such as stiffened panels fabricated out of high strength materials are ubiquitous in aerospace structures. These are prone to buckle in a variety of modes with strong possibility of adverse interaction under axial compression and/or bending. Optimally designed stiffened panels, at an appropriate combination of axial compression and suddenly applied lateral pressure undergo large amplitude oscillations and may experience divergence. Under aerodynamic loading, they can experience flutter instability with the amplitudes of oscillations attaining a limit (LCO) or escalating without any limit. Control of structures prone to these forms of instability using piezo-electric actuators is the theme of this dissertation. Issues involved in the control of stiffened panels under axial compression and liable to buckle simultaneously in local and overall modes are studied. The analytical approach employs finite elements in which are embedded periodic components of local buckling including the second order effects. It is shown that the adverse effects of mode interaction can be counteracted by simply controlling the overall bending of the stiffener by piezo-electric actuators attached its tips. Control is exercised by self-sensing actuators by direct negative feedback voltages proportional to the bending strains of the stiffener. In a dynamic loading environment, where vibrations are triggered by suddenly applied lateral pressure, negative velocity feedback is employed with voltages proportional to the bending strain-rate. The local plate oscillations are effectively controlled by a piezo-electric actuators placed along the longitudinal center line of the panel. The problem of flutter under aerodynamic pressure of stiffened panels in the linear and post-critical regimes is studied using modal analysis and finite strips. The analysis, control and interpretation of the response are facilitated by identification of two families of characteristic modes of

  8. The lateral line microcosmos. (United States)

    Ghysen, Alain; Dambly-Chaudière, Christine


    The lateral-line system is a simple sensory system comprising a number of discrete sense organs, the neuromasts, distributed over the body of fish and amphibians in species-specific patterns. Its development involves fundamental biological processes such as long-range cell migration, planar cell polarity, regeneration, and post-embryonic remodeling. These aspects have been extensively studied in amphibians by experimental embryologists, but it is only recently that the genetic bases of this development have been explored in zebrafish. This review discusses progress made over the past few years in this field.


    Krasnoperov, S N; Shishka, I V; Golovaha, M L


    Delayed diagnosis of acute lateral ankle ligaments injury and subsequent inadequate treatment leads to the development of chronic instability and rapid progression of degenerative processes in the joint. The aim of our work was to improve treatment results by developing an diagnostic algorithm and treatment strategy of acute lateral ankle ligament injuries. The study included 48 patients with history of acute inversion ankle injury mechanism. Diagnostic protocol included clinical and radiological examination during 48 hours and after 7-10 days after injury. According to the high rate of inaccurate clinical diagnosis in the first 48 hours of the injury a short course of conservative treatment for 7-10 days is needed with follow-up and controlling clinical and radiographic instability tests. Clinical symptoms of ankle inversion injury showed that the combination of local tenderness in the projection of damaged ligaments, the presence of severe periarticular hematoma in the lateral department and positive anterior drawer and talar tilt tests in 7-10 days after the injury in 87% of cases shows the presence of ligament rupture. An algorithm for diagnosis of acute lateral ankle ligament injury was developed, which allowed us to determine differential indications for surgical repair of the ligaments and conservative treatment of these patients.

  10. Creativity in later life. (United States)

    Price, K A; Tinker, A M


    The ageing population presents significant challenges for the provision of social and health services. Strategies are needed to enable older people to cope within a society ill prepared for the impacts of these demographic changes. The ability to be creative may be one such strategy. This review outlines the relevant literature and examines current public health policy related to creativity in old age with the aim of highlighting some important issues. As well as looking at the benefits and negative aspects of creative activity in later life they are considered in the context of the theory of "successful ageing". Creative activity plays an important role in the lives of older people promoting social interaction, providing cognitive stimulation and giving a sense of self-worth. Furthermore, it is shown to be useful as a tool in the multi-disciplinary treatment of health problems common in later life such as depression and dementia. There are a number of initiatives to encourage older people to participate in creative activities such as arts-based projects which may range from visual arts to dance to music to intergenerational initiatives. However, participation shows geographical variation and often the responsibility of provision falls to voluntary organisations. Overall, the literature presented suggests that creative activity could be a useful tool for individuals and society. However, further research is needed to establish the key factors which contribute to patterns of improved health and well-being, as well as to explore ways to improve access to services.

  11. Brainmining emotive lateral solutions

    Directory of Open Access Journals (Sweden)

    Theodore Scaltsas


    Full Text Available BrainMining is a theory of creative thinking that shows how we should exploit the mind’s spontaneous natural disposition to use old solutions to address new problems – our Anchoring Cognitive Bias. BrainMining develops a simple and straightforward method to transform recalcitrant problems into types of problems which we have solved before, and then apply an old type of solution to them. The transformation makes the thinking lateral by matching up disparate types of problem and solution. It emphasises the role of emotive judgements that the agent makes, when she discerns whether a change of the values or the emotions and feelings in a situation, which would expand the space of solutions available for the problem at hand, would be acceptable or appropriate in the situation. A lateral solution for an intractable problem is thus spontaneously brainmined from the agent’s old solutions, to solve a transformed version of the intractable problem, possibly involving changes in the value system or the emotional profile of the situation, which the agent judges, emotively, will be acceptable, and even appropriate in the circumstances.

  12. Lateral Lumbar Interbody Fusion (United States)

    Hughes, Alexander; Girardi, Federico; Sama, Andrew; Lebl, Darren; Cammisa, Frank


    The lateral lumbar interbody fusion (LLIF) is a relatively new technique that allows the surgeon to access the intervertebral space from a direct lateral approach either anterior to or through the psoas muscle. This approach provides an alternative to anterior lumbar interbody fusion with instrumentation, posterior lumbar interbody fusion, and transforaminal lumbar interbody fusion for anterior column support. LLIF is minimally invasive, safe, better structural support from the apophyseal ring, potential for coronal plane deformity correction, and indirect decompression, which have has made this technique popular. LLIF is currently being utilized for a variety of pathologies including but not limited to adult de novo lumbar scoliosis, central and foraminal stenosis, spondylolisthesis, and adjacent segment degeneration. Although early clinical outcomes have been good, the potential for significant neurological and vascular vertebral endplate complications exists. Nevertheless, LLIF is a promising technique with the potential to more effectively treat complex adult de novo scoliosis and achieve predictable fusion while avoiding the complications of traditional anterior surgery and posterior interbody techniques. PMID:26713134

  13. The effect of electro-thermal and electro-choric instabilities and material strength on MagLIF liner stability (United States)

    Pecover, James; Chittenden, Jeremy


    Magnetized liner inertial fusion (MagLIF) is a promising route to controlled thermonuclear fusion. The concept involves magnetically imploding a metal liner containing fuel with an azimuthal magnetic field (Bz) ; a key limitation of such systems is the magneto-Rayleigh-Taylor (MRT) instability. MagLIF relevant liner implosions with Bz = 0 carried out at SNL showed high amplitude MRT growth; we present a quantitative comparison between experimental results and 3D results from our MHD code Gorgon, demonstrating closer agreement for the MRT properties with the inclusion of electro-thermal and electro-choric instabilities (ETI and ECI) and material strength. The ETI and ECI result in early time azimuthally correlated structures which provide a seed for the MRT. Material strength increases the ETI amplitude due to positive feedback during the solid phase of the liner. Similar liner implosions with Bz exhibited a re-orientation of the MRT into helical structures, which are yet to be reproduced by simulations without an artificial helical initialisation. Our 3D Gorgon results with Bz show helices prior to vapourisation; these occur at initially positive angles before changing sign, tending to zero later in time. This angle does not follow the relative magnitudes of Bz and Bθ as would be expected for the MRT. The angle instead follows the ratio of axial and azimuthal currents (induced by compression or rarefaction of the initial Bz) , indicating an electro-thermal origin.

  14. Flow Enhancement due to Elastic Turbulence in Channel Flows of Shear Thinning Fluids (United States)

    Bodiguel, Hugues; Beaumont, Julien; Machado, Anaïs; Martinie, Laetitia; Kellay, Hamid; Colin, Annie


    We explore the flow of highly shear thinning polymer solutions in straight geometry. The strong variations of the normal forces close to the wall give rise to an elastic instability. We evidence a periodic motion close the onset of the instability, which then evolves towards a turbulentlike flow at higher flow rates. Strikingly, we point out that this instability induces genuine drag reduction due to the homogenization of the viscosity profile by the turbulent flow.

  15. Kinetic Theory of Instability-Enhanced Collisional Effects (United States)

    Baalrud, Scott D.


    A generalization of the Lenard-Balescu collision operator is derived which accounts for the scattering of particles by instability amplified fluctuations that originate from the thermal motion of discrete particles (in contrast to evoking a fluctuation level externally, as is done in quasilinear kinetic theory) [1]. Emphasis is placed on plasmas with convective instabilities. It is shown that an instability-enhanced collective response results which can be the primary mechanism for scattering particles, being orders of magnitude more frequent than conventional Coulomb collisions, even though the fluctuations are in a linear growth phase. The resulting collision operator is shown to obey conservation laws (energy, momentum, and density), Galilean invariance, and the Boltzmann H-theorem. It has the property that Maxwellian is the unique equilibrium distribution function; again in contrast to weak turbulence or quasilinear theories. Instability-enhanced collisional effects can dominate particle scattering and cause strong frictional forces. For example, this theory has been applied to two outstanding problems: Langmuir's paradox [2] and determining Bohm's criterion for plasmas with multiple ion species [3]. Langmuir's paradox is a measurement of anomalous electron scattering rapidly establishing a Maxwellian distribution in gas discharges with low temperature and pressure. This may be explained by instability-enhanced scattering in the plasma-boundary transition region (presheath) where convective ion-acoustic instabilities are excited. Bohm's criterion for multiple ion species is a single condition that the ion fluid speeds must obey at the sheath edge; but it is insufficient to determine the speed of individual species. It is shown that an instability-enhanced collisional friction, due to streaming instabilities in the presheath, determines this criterion.[4pt] [1] S.D. Baalrud, J.D. Callen, and C.C. Hegna, Phys. Plasmas 15, 092111 (2008).[0pt] [2] S.D. Baalrud, J

  16. Circumferential buckling instability of a growing cylindrical tube

    KAUST Repository

    Moulton, D.E.


    A cylindrical elastic tube under uniform radial external pressure will buckle circumferentially to a non-circular cross-section at a critical pressure. The buckling represents an instability of the inner or outer edge of the tube. This is a common phenomenon in biological tissues, where it is referred to as mucosal folding. Here, we investigate this buckling instability in a growing elastic tube. A change in thickness due to growth can have a dramatic impact on circumferential buckling, both in the critical pressure and the buckling pattern. We consider both single- and bi-layer tubes and multiple boundary conditions. We highlight the competition between geometric effects, i.e. the change in tube dimensions, and mechanical effects, i.e. the effect of residual stress, due to differential growth. This competition can lead to non-intuitive results, such as a tube growing to be thinner and yet buckle at a higher pressure. © 2011 Elsevier Ltd. All rights reserved.

  17. Novel case of Trevor’s disease: Adult onset and later recurrence (United States)

    Khalsa, Amrit S; Kumar, Neil S; Chin, Matthew A; Lackman, Richard D


    Dysplasia epiphysealis hemimelica (DEH), or Trevor’s disease, is an osteocartilaginous epiphyseal overgrowth typically occurring in children. The literature reports 6 adult cases and none describe recurrence requiring additional procedures. We present a new-onset proximal tibial DEH in an adult recurring approximately 3 years after open excision. A 39-year-old female presented with a history of right knee pain, swelling, and instability. Physical examination revealed a firm proximal tibial mass. Computed tomography (CT) imaging showed an exophytic, lobulated, sclerotic mass involving the anterolateral margin of the lateral tibial plateau. Magnetic resonance imaging was suggestive of an osteochondroma. The patient underwent curettage of the lesion due to its periarticular location. Histology revealed benign and reactive bone and cartilage consistent with periosteal chondroma. Two and a half years later, the patient presented with a firm, palpable mass larger than the initial lesion. CT revealed a lateral tibial plateau sclerotic mass consistent with recurrent intra-articular DEH. A complete excision was performed and histology showed sclerotic bone with overlying cartilage consistent with exostosis. DEH is a rare epiphyseal osteocartilaginous outgrowth frequently occurring in the long bones of children less than 8 years old. DEH resembles an osteochondroma due to its pediatric presentation and similar histologic appearance. Adult-onset cases comprise less than 1% of reported cases. Recurrence rate after surgical intervention is unknown. Only 1 such case, occurring in a child, has been described. Clinicians contemplating operative treatment for DEH should note the potential for recurrence and consider complete excision. A follow-up period of several years may be warranted to identify recurrent lesions. PMID:28144583

  18. Modes of storage ring coherent instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J.M.


    Longitudinal impedance in a beam and various modes of longitudinal coherent instabilities are discussed. The coasting beam coherent instability, microwave instability, and single-bunch longitudinal coherent instabilities are considered. The Vlasov equation is formulated, and a method of solving it is developed. The synchrotron modes are treated, which take the possible bunch shape distortion fully into consideration. A method of treating the synchrotron mode coupling in the case of a small bunch is discussed which takes advantage of the fact that only a few of the synchrotron modes can contribute in such a case. The effect of many bunches on the coherent motion of the beam and the longitudinal symmetric coupled bunch modes are discussed. The transverse impedance is then introduced, and the transverse coasting beam instability is discussed. Various bunched beam instabilities are discussed, including both single bunch instabilities and coupled bunch instabilities. The Vlasov equation for transverse as well as longitudinal motion of particles is introduced as well as a method of solving it within a linear approximation. Head-tail modes and short bunch instabilities and strong coupling instabilities in the long bunch case are covered. (LEW)

  19. Lateral sided snapping elbow caused by a meniscus: two case reports and literature review. (United States)

    Kang, Shin-Taek; Kim, Tae-Ho


    Lateral sided snapping elbow is an unusual condition, and it is apt to be misdiagnosed as lateral epicondylitis. The causes of lateral sided snapping elbow have been attributed to intraarticular loose bodies, instability, synovial plicae and torn annular ligament. We report our experiences for treating lateral sided snapping elbow caused by a meniscus in the radio-humeral joint. In the present cases, the cause of snapping was detected using double contrast arthrogram under fluoroscopic control, and histology revealed that it was a meniscus. Complete removal of the meniscus allowed immediate relief of the symptom, and there was no recurrence in both cases.

  20. On phase change in Marangoni-driven flows and its effects on the hydrothermal-wave instabilities (United States)

    Sáenz, P. J.; Valluri, P.; Sefiane, K.; Karapetsas, G.; Matar, O. K.


    This paper investigates the effects of phase change on the stability of a laterally heated liquid layer for the first time. The interface is open to the atmosphere and vapor diffusion is the rate-limiting mechanism for evaporation. In this configuration, the planar layer is naturally vulnerable to the formation of travelling thermal instabilities, i.e., hydrothermal waves (HTWs), due to the presence of temperature gradients along the gas-liquid interface. Recent work carried out for deformable interfaces and negligible evaporation indicates that the HTWs additionally give rise to interface deformations of similar features, i.e., physical waves. The study presented here reveals that phase change plays a dual role through its effect on these instabilities: the latent energy required during the evaporation process tends to inhibit the HTWs while the accompanying level reduction enhances the physical waves by minimizing the role of gravity. The dynamics of the gas phase are also discussed. The HTW-induced convective patterns in the gas along with the travelling nature of the instabilities have a significant impact on the local evaporation flux and the vapor distribution above the interface. Interestingly, high (low) concentrations of vapor are found above cold (hot) spots. The phase-change mechanism for stable layers is also investigated. The Marangoni effect plays a major role in the vapor distribution generating a vacuum effect in the warm region and vapor accumulations at the cold boundary capable of inverting the phase change, i.e., the capillary flow can lead to local condensation. This work also demonstrates the inefficiencies of the traditional phase change models based on pure vapor diffusion to capture the dynamics of thermocapillary flows.

  1. The Cause and Mechanism of Cardiac Electrical Instability. Defibrillation Mechanism

    Directory of Open Access Journals (Sweden)

    Rustam G. Habchabov


    Full Text Available The reason for the ominous arrhythmias pathway, causing sudden somatic death from cardiovascular diseases is still not clear, cardiological examinations of this phenomenon are conducted throughout the world. Laceration of connective insulating tissue membrane of heart pathway with ectopic nodes oxidation may cause ominous arrhythmias; nobody has considered this cause as a cardiac electrical instability before. Defibrillator electric discharges cannot penetrate into myocardium due to the connective insulating tissue membrane, nobody has considered nervous system, transmitting electricity.

  2. Application of Detailed Chemical Kinetics to Combustion Instability Modeling (United States)


    under two different conditions corresponding to marginally stable and unstable operation in order to evaluate the performance of the chemical kinetics...instability is a complex interaction between acoustics and the heat release due to combustion.In rocket engines, which are acoustically compact, there is...and amplitudes remains a challenge. The present article is an attempt towards addressing such discrepancies by enhancing the chemical kinetics model

  3. Language lateralization shifts with learning by adults. (United States)

    Plante, Elena; Almryde, Kyle; Patterson, Dianne K; Vance, Christopher J; Asbjørnsen, Arve E


    For the majority of the population, language is a left-hemisphere lateralized function. During childhood, a pattern of increasing left lateralization for language has been described in brain imaging studies, suggesting that this trait develops. This development could reflect change due to brain maturation or change due to skill acquisition, given that children acquire and refine language skills as they mature. We test the possibility that skill acquisition, independent of age-associated maturation can result in shifts in language lateralization in classic language cortex. We imaged adults exposed to an unfamiliar language during three successive fMRI scans. Participants were then asked to identify specific words embedded in Norwegian sentences. Exposure to these sentences, relative to complex tones, resulted in consistent activation in the left and right superior temporal gyrus. Activation in this region became increasingly left-lateralized with repeated exposure to the unfamiliar language. These results demonstrate that shifts in lateralization can be produced in the short term within a learning context, independent of maturation.

  4. Symmetry-breaking instability in a prototypical driven granular gas. (United States)

    Khain, Evgeniy; Meerson, Baruch


    Symmetry-breaking instability of a laterally uniform granular cluster (strip state) in a prototypical driven granular gas is investigated. The system consists of smooth hard disks in a two-dimensional box, colliding inelastically with each other and driven, at zero gravity, by a "thermal" wall. The limit of nearly elastic particle collisions is considered, and granular hydrodynamics with the Jenkins-Richman constitutive relations is employed. The hydrodynamic problem is completely described by two scaled parameters and the aspect ratio of the box. Marginal stability analysis predicts a spontaneous symmetry-breaking instability of the strip state, similar to that predicted recently for a different set of constitutive relations. If the system is big enough, the marginal stability curve becomes independent of the details of the boundary condition at the driving wall. In this regime, the density perturbation is exponentially localized at the elastic wall opposite the thermal wall. The short- and long-wavelength asymptotics of the marginal stability curves are obtained analytically in the dilute limit. The physics of the symmetry-breaking instability is discussed.

  5. Prevention and management of post-instability glenohumeral arthropathy (United States)

    Waterman, Brian R; Kilcoyne, Kelly G; Parada, Stephen A; Eichinger, Josef K


    Post-instability arthropathy may commonly develop in high-risk patients with a history of recurrent glenohumeral instability, both with and without surgical stabilization. Classically related to anterior shoulder instability, the incidence and rates of arthritic progression may vary widely. Radiographic arthritic changes may be present in up to two-thirds of patients after primary Bankart repair and 30% after Latarjet procedure, with increasing rates associated with recurrent dislocation history, prominent implant position, non-anatomic reconstruction, and/or lateralized bone graft placement. However, the presence radiographic arthrosis does not predict poor patient-reported function. After exhausting conservative measures, both joint-preserving and arthroplasty surgical options may be considered depending on a combination of patient-specific and anatomic factors. Arthroscopic procedures are optimally indicated for individuals with focal disease and may yield superior symptomatic relief when combined with treatment of combined shoulder pathology. For more advanced secondary arthropathy, total shoulder arthroplasty remains the most reliable option, although the clinical outcomes, wear characteristics, and implant survivorship remains a concern among active, young patients. PMID:28361016

  6. Effect of Fluorosurfactant on Capillary Instabilities in Nanoimprinted Polymer Patterns

    Energy Technology Data Exchange (ETDEWEB)

    Alvine, Kyle J.; Ding, Yifu; Douglas, Jack F.; Ro, Hyun W.; Okerberg, Brian C.; Karim, Alamgir; Lavery, Kristopher A.; Lin-Gibson, Sheng; Soles, Christopher L.


    Surface forces play a paramount role in most aspects of Nanoimprint Lithography. In particular, subjecting nanoimprinted patterns to moderate heating allows surface tension to smooth out undesirable roughness and defects in the patterns, but this thermal reflow treatment can induce structural decay or even collapse of the patterns by capillary instability if this process is not carefully controlled. Adhesion between the mold and polymer film can also cause the imprinted structure to tear or fracture. Fluorinated surfactants (FS) are attractive for reducing mold adhesion, yet the effects of these additives on nanostructure stability during thermal reflow are not well understood. Here we present thermal stability studies of line-space grating patterns created by Thermal Embossing Nanoimprint Lithography (TENIL) on model polystyrene (PS) films with FS additives. As expected by energy considerations, FS segregates to the air interface where it seems to facilitate mold release. This also reduces the surface energy and thus reduces the driving force for pattern "slumping" (height decay). However, the beneficial effects of the surfactant are counterbalanced by the fact that the FS decreases the effective film viscosity, which accelerates nanopattern leveling. The net effect is that the pattern height decay is strongly a function of FS concentration. This enhanced film fluidity in the presence of FS also makes the pattern more susceptible to an undulatory capillary instability under thermal reflow conditions. Surface phase segregation of FS and PS is also observed in conjunction with both slumping and lateral capillary instabilities, which may be useful for producing chemically patterned surfaces.

  7. Diagnostic of patellar instability after total knee arthroplasty

    Directory of Open Access Journals (Sweden)

    T. V. Zhizhenkova


    Full Text Available Objectives - to identify main reasons of patella instability after primary total knee arthroplasty, and to determine further treatment strategy of this complication. Material and methods. Since 2011 till 2014 1098 total knee arthroplasties have been performed in Yaroslavl Regional Hospital for Veterans of Wars. We observed 14 (1.3% patients with postoperative patella instability The evaluation included clinical and radiographic methods. Rotational alignment of the femoral and tibial components was studied by computed tomography (CT scanner. Conclusion. Position of the femoral components ranged from 2° excessive external to 8° excessive internal rotation. Position of the tibial components ranged from 0° to 6° excessive internal rotation. The summary endoprosthetic position ranged from 1 ° to 10° excessive internal rotation. We found direct correlation between summary implant internal rotation and the severity of postoperative complications in patellafemoral joint. Results. The main reason of the patella instability is implant summary internal malrotation. Extensive lateral release with patella resurfacing was sufficient for pain relief and tracking correction if the combined internal rotation did not exceed 6°. Large value of internal malrotation was the indication for revision surgery with selective approach.

  8. [Kelvin-Helmholtz instability in protostellar jets (United States)

    Stone, James; Hardee, Philip


    NASA grant NAG 5 2866, funded by the Astrophysics Theory Program, enabled the study the Kelvin-Helmholtz instability in protostellar jets. In collaboration with co-investigator Philip Hardee, the PI derived the analytic dispersion relation for the instability in including a cooling term in the energy equation which was modeled as one of two different power laws. Numerical solutions to this dispersion relation over a wide range of perturbation frequencies, and for a variety of parameter values characterizing the jet (such as Mach number, and density ratio) were found It was found that the growth rates and wavelengths associated with unstable roots of the dispersion relation in cooling jets are significantly different than those associated with adiabatic jets, which have been studied previously. In collaboration with graduate student Jianjun Xu (funded as a research associate under this grant), hydrodynamical simulations were used to follow the growth of the instability into the nonlinear regime. It was found that asymmetric surface waves lead to large amplitude, sinusoidal distortions of the jet, and ultimately to disruption Asymmetric body waves, on the other hand, result in the formation of shocks in the jet beam in the nonlinear regime. In cooling jets, these shocks lead to the formation of dense knots and filaments of gas within the jet. For sufficiently high perturbation frequencies, however, the jet cannot respond and it remains symmetric. Applying these results to observed systems, such as the Herbig-Haro jets HH34, HH111 and HH47 which have been observed with the Hubble Space Telescope, we predicted that some of the asymmetric structures observed in these systems could be attributed to the K-H modes, but that perturbations on timescales associated with the inner disk (about 1 year) would be too rapid to cause disruption. Moreover, it was discovered that weak shock 'spurs' in the ambient gas produced by ripples in the jet surface due to nonlinear, modes of

  9. Effects of Lateral Mass Screw Rod Fixation to the Stability of Cervical Spine after Laminectomy (United States)

    Rosli, Ruwaida; Kashani, Jamal; Kadir, Mohammed Rafiq Abdul

    There are many cases of injury in the cervical spine due to degenerative disorder, trauma or instability. This condition may produce pressure on the spinal cord or on the nerve coming from the spine. The aim of this study was, to analyze the stabilization of the cervical spine after undergoing laminectomy via computational simulation. For that purpose, a three-dimensional finite element (FE) model for the multilevel cervical spine segment (C1-C7) was developed using computed tomography (CT) data. There are various decompression techniques that can be applied to overcome the injury. Usually, decompression procedures will create an unstable spine. Therefore, in these situations, the spine is often surgically restabilized by using fusion and instrumentation. In this study, a lateral mass screw-rod fixation was created to stabilize the cervical spine after laminectomy. Material properties of the titanium alloy were assigned on the implants. The requirements moments and boundary conditions were applied on simulated implanted bone. Result showed that the bone without implant has a higher flexion and extension angle in comparison to the bone with implant under applied 1Nm moment. The bone without implant has maximum stress distribution at the vertebrae and ligaments. However, the bone with implant has maximum stress distribution at the screws and rods. Overall, the lateral mass screw-rod fixation provides stability to the cervical spine after undergoing laminectomy.

  10. Epicondilite lateral do cotovelo


    Cohen,Marcio; Motta Filho,Geraldo da Rocha


    A epicondilite lateral, também conhecida como cotovelo do tenista, é uma condição comum que acomete de 1 a 3% da população. O termo epicondilite sugere inflamação, embora a análise histológica tecidual não demonstre um processo inflamatório. A estrutura acometida com mais frequência é a origem do tendão extensor radial curto do carpo e o mecanismo de lesão está associado à sua sobrecarga. O tratamento incruento é o de escolha e inclui: repouso, fisioterapia, infiltração com cortisona ou plasm...

  11. Vitiligo Lateral Lower Lip

    Directory of Open Access Journals (Sweden)

    Sahoo Antaryami


    Full Text Available Vitiligo characteristically affecting the lateral lower lip (LLL is a common presentation in South Orissa. This type of lesion has rarely been described in literature. One hundred eighteen such cases were studied during the period from October 1999 to September, 2000. LLL vitiligo constituted 16.39% of all vitiligo patients. Both sexes were affected equally. The peak age of onset was in the 2nd decade, mean duration of illness 21.46 months. Fifty six patients had unilateral lesion (38 on the left and 18 on the right. Among the 62 patients having bilateral lesions, the onset was more frequent on the left (38 than either the right (8 or both sides together (16. All the patients were right handed. Association with local factors like infection, trauma, cheilitis, FDE etc were associated in 38.98% of cases, but systemic or autoimmune diseases were not associated. Positive family history was found in 22% of cases.

  12. Lateral conduction infrared photodetector (United States)

    Kim, Jin K.; Carroll, Malcolm S.


    A photodetector for detecting infrared light in a wavelength range of 3-25 .mu.m is disclosed. The photodetector has a mesa structure formed from semiconductor layers which include a type-II superlattice formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5. Impurity doped regions are formed on sidewalls of the mesa structure to provide for a lateral conduction of photo-generated carriers which can provide an increased carrier mobility and a reduced surface recombination. An optional bias electrode can be used in the photodetector to control and vary a cut-off wavelength or a depletion width therein. The photodetector can be formed as a single-color or multi-color device, and can also be used to form a focal plane array which is compatible with conventional read-out integrated circuits.

  13. Invited Review. Combustion instability in spray-guided stratified-charge engines. A review

    Energy Technology Data Exchange (ETDEWEB)

    Fansler, Todd D. [Univ. of Wisconsin, Madison, WI (United States); Reuss, D. L. [Univ. of Michigan, Ann Arbor, MI (United States); Sandia National Lab. (SNL-CA), Livermore, CA (United States); Sick, V. [Univ. of Michigan, Ann Arbor, MI (United States); Dahms, R. N. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)


    Our article reviews systematic research on combustion instabilities (principally rare, random misfires and partial burns) in spray-guided stratified-charge (SGSC) engines operated at part load with highly stratified fuel -air -residual mixtures. Results from high-speed optical imaging diagnostics and numerical simulation provide a conceptual framework and quantify the sensitivity of ignition and flame propagation to strong, cyclically varying temporal and spatial gradients in the flow field and in the fuel -air -residual distribution. For SGSC engines using multi-hole injectors, spark stretching and locally rich ignition are beneficial. Moreover, combustion instability is dominated by convective flow fluctuations that impede motion of the spark or flame kernel toward the bulk of the fuel, coupled with low flame speeds due to locally lean mixtures surrounding the kernel. In SGSC engines using outwardly opening piezo-electric injectors, ignition and early flame growth are strongly influenced by the spray's characteristic recirculation vortex. For both injection systems, the spray and the intake/compression-generated flow field influence each other. Factors underlying the benefits of multi-pulse injection are identified. Finally, some unresolved questions include (1) the extent to which piezo-SGSC misfires are caused by failure to form a flame kernel rather than by flame-kernel extinction (as in multi-hole SGSC engines); (2) the relative contributions of partially premixed flame propagation and mixing-controlled combustion under the exceptionally late-injection conditions that permit SGSC operation on E85-like fuels with very low NOx and soot emissions; and (3) the effects of flow-field variability on later combustion, where fuel-air-residual mixing within the piston bowl becomes important.

  14. Varying chromaticity: A damping mechanism for the transverse head-tail instability

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, W.; Wurtele, J.S. [Department of Physics, University of California at Berkeley, Berkeley, California 94720 (United States); Sessler, A.M.; Wurtele, J.S. [Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States)


    A detailed analytical and numerical study of the suppression of the transverse head-tail instability by modulating the chromaticity over a synchrotron period is presented. We find that a threshold can be developed, and it can be increased to a value larger than the strong head-tail instability threshold. The stability criterion derived agrees very well with the simulations. The underlying physical mechanisms of the damping scheme are rotation of the head-tail phase such that the instability does not occur, and Landau damping due to the incoherent betatron tune spread generated by the varying chromaticity. {copyright} {ital 1997} {ital The American Physical Society}

  15. Instability of the origami of a ferrofluid drop in a magnetic field

    CERN Document Server

    Jamin, Timothée; Falcon, Eric


    Capillary origami is the wrapping of an usual fluid drop by a planar elastic membrane due to the interplay between capillary and elastic forces. Here, we use a drop of magnetic fluid whose shape is known to strongly depend on an applied magnetic field. We study the quasi-static and dynamical behaviors of such a magnetic capillary origami. We report the observation of an overturning instability that the origami undergoes at a critical magnetic field. This instability is triggered by an interplay between magnetic and gravitational energies in agreement with the theory presented here. Additional effects of elasticity and capillarity on this instability are also discussed.

  16. Bathtub vortex induced by instability (United States)

    Mizushima, Jiro; Abe, Kazuki; Yokoyama, Naoto


    The driving mechanism and the swirl direction of the bathtub vortex are investigated by the linear stability analysis of the no-vortex flow as well as numerical simulations. We find that only systems having plane symmetries with respect to vertical planes deserve research for the swirl direction. The bathtub vortex appearing in a vessel with a rectangular cross section having a drain hole at the center of the bottom is proved to be induced by instability when the flow rate exceeds a threshold. The Coriolis force is capable of determining the swirl direction to be cyclonic.

  17. Spatiotemporal chaos involving wave instability (United States)

    Berenstein, Igal; Carballido-Landeira, Jorge


    In this paper, we investigate pattern formation in a model of a reaction confined in a microemulsion, in a regime where both Turing and wave instability occur. In one-dimensional systems, the pattern corresponds to spatiotemporal intermittency where the behavior of the systems alternates in both time and space between stationary Turing patterns and traveling waves. In two-dimensional systems, the behavior initially may correspond to Turing patterns, which then turn into wave patterns. The resulting pattern also corresponds to a chaotic state, where the system alternates in both space and time between standing wave patterns and traveling waves, and the local dynamics may show vanishing amplitude of the variables.

  18. Nonlinear Instability of Liquid Layers. (United States)

    Newhouse, Lori Ann

    The nonlinear instability of two superposed viscous liquid layers in planar and axisymmetric configurations is investigated. In the planar configuration, the light layer fluid is bounded below by a wall and above by a heavy semiinfinite fluid. Gravity drives the instability. In the first axisymmetric configuration, the layer is confined between a cylindrical wall and a core of another fluid. In the second, a thread is suspended in an infinite fluid. Surface tension forces drive the instability in the axisymmetric configurations. The nonlinear evolution of the fluid-fluid interface is computed for layers of arbitrary thickness when their dynamics are fully coupled to those of the second fluid. Under the assumption of creeping flow, the flow field is represented by an interfacial distribution of Green's functions. A Fredholm integral equation of the second kind for the strength of the distribution is derived and then solved using an iterative technique. The Green's functions produce flow fields which are periodic in the direction parallel to the wall and have zero velocity on the wall. For small and moderate surface tension, planar layers evolve into a periodic array of viscous plumes which penetrate into the overlying fluid. The morphology of the plumes depends on the surface tension and the ratio of the fluid viscosities. As the viscosity of the layer increases, the plumes change from a well defined drop on top of a narrow stem to a compact column of rising fluid. The capillary instability of cylindrical interfaces and interfaces in which the core thickness varies in the axial direction are investigated. In both the unbounded and wall bounded configurations, the core evolves into a periodic array of elongated fluid drops connected by thin, almost cylindrical fluid links. The characteristics of the drop-link structure depend on the core thickness, the ratio of the core radius to the wall radius, and the ratio of the fluid viscosities. The factors controlling the

  19. Particle-in-cell simulations of velocity scattering of an anisotropic electron beam by electrostatic and electromagnetic instabilities (United States)

    Fu, X. R.; Cowee, M. M.; Liu, K.; Peter Gary, S.; Winske, D.


    The velocity space scattering of an anisotropic electron beam (T⊥b/T∥b>1) flowing along a background magnetic field B0 through a cold plasma is investigated using both linear theory and 2D particle-in-cell simulations. Here, ⊥ and ∥ represent the directions perpendicular and parallel to B0, respectively. In this scenario, we find that two primary instabilities contribute to the scattering in electron pitch angle: an electrostatic electron beam instability and a predominantly parallel-propagating electromagnetic whistler anisotropy instability. Our results show that at relative beam densities nb/ne≤0.05 and beam temperature anisotropies Tb ⊥/Tb ∥≤25, the electrostatic beam instability grows much faster than the whistler instabilities for a reasonably fast hot beam. The enhanced fluctuating fields from the beam instability scatter the beam electrons, slowing their average speed and increasing their parallel temperature, thereby increasing their pitch angles. In an inhomogeneous magnetic field, such as the geomagnetic field, this could result in beam electrons scattered out of the loss cone. After saturation of the electrostatic instability, the parallel-propagating whistler anisotropy instability shows appreciable growth, provided that the beam density and late-time anisotropy are sufficiently large. Although the whistler anisotropy instability acts to pitch-angle scatter the electrons, reducing perpendicular energy in favor of parallel energy, these changes are weak compared to the pitch-angle increases resulting from the deceleration of the beam due to the electrostatic instability.

  20. From Maxwell's theory of Saturn's rings to the negative mass instability. (United States)

    Fedele, Renato


    The impact of Maxwell's theory of Saturn's rings, formulated in Aberdeen ca 1856, is discussed. One century later, Nielsen, Sessler and Symon formulated a similar theory to describe the coherent instabilities (in particular, the negative mass instability) exhibited by a charged particle beam in a high-energy accelerating machine. Extended to systems of particles where the mutual gravitational attraction is replaced by the electric repulsion, Maxwell's approach was the conceptual basis to formulate the kinetic theory of coherent instability (Vlasov-Maxwell system), which, in particular, predicts the stabilizing role of the Landau damping. However, Maxwell's idea was so fertile that, later on, it was extended to quantum-like models (e.g. thermal wave model), providing the quantum-like description of coherent instability (Schrödinger-Maxwell system) and its identification with the modulational instability (MI). The latter has recently been formulated for any nonlinear wave propagation governed by the nonlinear Schrödinger equation, as in the statistical approach to MI (Wigner-Maxwell system). It seems that the above recent developments may provide a possible feedback to Maxwell's original idea with the extension to quantum gravity and cosmology.

  1. Instabilities of collisionless current sheets revisited: the role of anisotropic heating

    CERN Document Server

    Muñoz, P A; Büchner, J


    In this work, we investigate the influence of the anisotropic heating on the spontaneous instability and evolution of thin Harris-type collisionless current sheets, embedded in antiparallel magnetic fields. In particular, we explore the influence of the macroparticle shape-function using a 2D version of the PIC code ACRONYM. We also investigate the role of the numerical collisionality due to the finite number of macroparticles in PIC codes. It is shown that it is appropriate to choose higher order shape functions of the macroparticles compared to a larger number of macroparticles per cell. This allows to estimate better the anisotropic electron heating due to the collisions of macroparticles in a PIC code. Temperature anisotropies can stabilize the tearing mode instability and trigger additional current sheet instabilities. We found a good agreement between the analytically derived threshold for the stabilization of the anisotropic tearing mode and other instabilities, either spontaneously developing or initi...

  2. Superfluid instability of r-modes in "differentially rotating" neutron stars

    CERN Document Server

    Andersson, N; Hogg, M


    Superfluid hydrodynamics affects the spin-evolution of mature neutron stars, and may be key to explaining timing irregularities such as pulsar glitches. However, most models for this phenomenon exclude the global instability required to trigger the event. In this paper we discuss a mechanism that may fill this gap. We establish that small scale inertial r-modes become unstable in a superfluid neutron star that exhibits a rotational lag, expected to build up due to vortex pinning as the star spins down. Somewhat counterintuitively, this instability arises due to the (under normal circumstances dissipative) vortex-mediated mutual friction. We explore the nature of the superfluid instability for a simple incompressible model, allowing for entrainment coupling between the two fluid components. Our results recover a previously discussed dynamical instability in systems where the two components are strongly coupled. In addition, we demonstrate for the first time that the system is secularly unstable (with a growth ...

  3. The inhomogeneous ion temperature anisotropy instabilities of magnetic-field-aligned plasma sheared flow (United States)

    Mikhailenko, V. V.; Mikhailenko, V. S.; Lee, Hae June


    The stability of the magnetic field aligned sheared flow with anisotropic ion temperatures, which have the anisotropic spatial inhomogeneities across the magnetic field and are comparable with or are above the electron temperature, is investigated numerically and analytically. The ion temperatures gradients across the magnetic field affect the instability development only when the inhomogeneous is the ion temperature along the magnetic field irrespective the inhomogeneity of the ion temperature across the magnetic field. In this case, the instability is developed due to the combined effect of the ion Landau damping, velocity shear, ion temperature anisotropy, and anisotropy of the ion temperature gradients. In the case when the ion temperature along the magnetic field is homogeneous, but the ion temperature across the magnetic field is inhomogeneous, the short wavelength instability develops with the wave length less than the thermal ion Larmor radius. This instability excites due to the coupled effect of the ion Landau damping, velocity shear and ion temperature anisotropy.

  4. Parametric instabilities of large-amplitude parallel propagating Alfven waves: 2-D PIC simulation

    CERN Document Server

    Nariyuki, Yasuhiro; Hada, Tohru


    We discuss the parametric instabilities of large-amplitude parallel propagating Alfven waves using the 2-D PIC simulation code. First, we confirmed the results in the past study [Sakai et al, 2005] that the electrons are heated due to the modified two stream instability and that the ions are heated by the parallel propagating ion acoustic waves. However, although the past study argued that such parallel propagating longitudinal waves are excited by transverse modulation of parent Alfven wave, we consider these waves are more likely to be generated by the usual, parallel decay instability. Further, we performed other simulation runs with different polarization of the parent Alfven waves or the different ion thermal velocity. Numerical results suggest that the electron heating by the modified two stream instability due to the large amplitude Alfven waves is unimportant with most parameter sets.

  5. Assessment of Lateral Driving Stability of Automobiles Passing by the Pylon Zone under Cross Wind

    Directory of Open Access Journals (Sweden)

    Dalei Wang


    Full Text Available In order to explore the reason of lateral instability of automobile passing by the pylon zone of cablesupported bridge under cross wind, a new evaluation method of lateral driving stability of automobile considering alternative cross wind is established based on multi-objective driving stability criteria and subjective assessment. Typical driving control process and dynamic response of automobile passing by the pylon zone is given by numerical simulation based on steering wheel fixed-control model and straight driving ideal-driver model. Finally, taking a medium-size commercial bus as an example, the reason of its lateral instability is interpreted and the influence of cross wind speed and driving speed on its lateral driving stability is shown by parameter study.

  6. Numerical simulations of thermal-chemical instabilities at the core-mantle boundary (United States)

    Hansen, Ulrich; Yuen, David A.


    Numerical simulations of thermal-chemical instabilities in the D-double-prime layer at the core-mantle boundary are presented which show that strong lateral heterogeneities in the composition and density fields can be initiated and maintained dynamically if there is continuous replenishment of material from subduced slabs coming from the upper mantle. These chemical instabilities have a tendency to migrate laterally and may help to support core-mantle boundary topography with short and long wavelengths. The thermal-chemical flows produce a relatively stagnant D-double-prime layer with strong lateral and temporal variations in basal heat flux, which gives rise to thermal core-mantle interactions influencing the geodynamo.

  7. Mode-locking via dissipative Faraday instability (United States)

    Tarasov, Nikita; Perego, Auro M.; Churkin, Dmitry V.; Staliunas, Kestutis; Turitsyn, Sergei K.


    Emergence of coherent structures and patterns at the nonlinear stage of modulation instability of a uniform state is an inherent feature of many biological, physical and engineering systems. There are several well-studied classical modulation instabilities, such as Benjamin-Feir, Turing and Faraday instability, which play a critical role in the self-organization of energy and matter in non-equilibrium physical, chemical and biological systems. Here we experimentally demonstrate the dissipative Faraday instability induced by spatially periodic zig-zag modulation of a dissipative parameter of the system--spectrally dependent losses--achieving generation of temporal patterns and high-harmonic mode-locking in a fibre laser. We demonstrate features of this instability that distinguish it from both the Benjamin-Feir and the purely dispersive Faraday instability. Our results open the possibilities for new designs of mode-locked lasers and can be extended to other fields of physics and engineering.

  8. Optimal excitation of two dimensional Holmboe instabilities

    CERN Document Server

    Constantinou, Navid C


    Highly stratified shear layers are rendered unstable even at high stratifications by Holmboe instabilities when the density stratification is concentrated in a small region of the shear layer. These instabilities may cause mixing in highly stratified environments. However these instabilities occur in tongues for a limited range of parameters. We perform Generalized Stability analysis of the two dimensional perturbation dynamics of an inviscid Boussinesq stratified shear layer and show that Holmboe instabilities at high Richardson numbers can be excited by their adjoints at amplitudes that are orders of magnitude larger than by introducing initially the unstable mode itself. We also determine the optimal growth that obtains for parameters for which there is no instability. We find that there is potential for large transient growth regardless of whether the background flow is exponentially stable or not and that the characteristic structure of the Holmboe instability asymptotically emerges for parameter values ...

  9. Mode-locking via dissipative Faraday instability. (United States)

    Tarasov, Nikita; Perego, Auro M; Churkin, Dmitry V; Staliunas, Kestutis; Turitsyn, Sergei K


    Emergence of coherent structures and patterns at the nonlinear stage of modulation instability of a uniform state is an inherent feature of many biological, physical and engineering systems. There are several well-studied classical modulation instabilities, such as Benjamin-Feir, Turing and Faraday instability, which play a critical role in the self-organization of energy and matter in non-equilibrium physical, chemical and biological systems. Here we experimentally demonstrate the dissipative Faraday instability induced by spatially periodic zig-zag modulation of a dissipative parameter of the system-spectrally dependent losses-achieving generation of temporal patterns and high-harmonic mode-locking in a fibre laser. We demonstrate features of this instability that distinguish it from both the Benjamin-Feir and the purely dispersive Faraday instability. Our results open the possibilities for new designs of mode-locked lasers and can be extended to other fields of physics and engineering.

  10. Shear dynamo, turbulence, and the magnetorotational instability (United States)

    Squire, Jonathan

    turbulence. This is studied using nonmodal stability theory, which both provides a highly intuitive connection between global domains and the commonly studied shearing box, and suggests that transient linear growth can often be more important than spectral instability. These realizations motivate the use of the quasi-linear models that are applied extensively throughout the turbulence and dynamo studies later in the thesis.

  11. Instabilities and transition in boundary layers

    Indian Academy of Sciences (India)

    N Vinod; Rama Govindarajan


    Some recent developments in boundary layer instabilities and transition are reviewed. Background disturbance levels determine the instability mechanism that ultimately leads to turbulence. At low noise levels, the traditional Tollmien–Schlichting route is followed, while at high levels, a `by-pass' route is more likely. Our recent work shows that spot birth is related to the pattern of secondary instability in either route.

  12. Beam Instabilities in the Scale Free Regime

    CERN Document Server

    Folli, Viola; Conti, Claudio; 10.1103/PhysRevLett.108.033901


    The instabilities arising in a one-dimensional beam sustained by the diffusive photorefractive nonlinearity in out-of-equilibrium ferroelectrics are theoretically and numerically investigated. In the "scale-free model", in striking contrast with the well-known spatial modulational instability, two different beam instabilities dominate: a defocusing and a fragmenting process. Both are independent of the beam power and are not associated to any specific periodic pattern.

  13. Electron proton instability in the CSNS ring

    Institute of Scientific and Technical Information of China (English)

    WANG Na; QIN Qing; LIU Yu-Dong


    The electron proton(e-p)instability has been observed in many proton accelerators.It will induce transverse beam size blow-up,cause beam loss and restrict the machine performance.Much research work has been done on the causes,dynamics and cures of this instability.A simulation code is developed to study the e-p instability in the ring of the China Spallation Neutron Source(CSNS).

  14. Fishbone Instability Excited by Barely Trapped Electrons

    Institute of Scientific and Technical Information of China (English)

    WANG Zhong-Tian; LONG Yong-Xing; DONG Jia-Qi; WANG Long; Fulvio Zonca


    Fishbone instability excited by barely trapped suprathermal electrons (BTSEs) in tokamaks is investigated theoretically. The frequency of the mode is found to close to procession frequency of BTSEs. The growth rate of the mode is much smaller than that of the ideal magnetohytrodynamic (MHD) internal kink mode that is in contrast to the case of trapped ion driven fishbone instability. The analyses also show that spatial density gradient reversal is necessary for the instability. The correlation of the results with experiments is discussed.

  15. Elimination of the numerical Cerenkov instability for spectral EM-PIC codes

    CERN Document Server

    Yu, Peicheng; Decyk, Viktor K; Fiuza, F; Vieira, Jorge; Tsung, Frank S; Fonseca, Ricardo A; Lu, Wei; Silva, Luis O; Mori, Warren B


    When using an electromagnetic particle-in-cell (EM-PIC) code to simulate a relativistically drifting plasma, a violent numerical instability known as the numerical Cerenkov instability (NCI) occurs. The NCI is due to the unphysical coupling of electromagnetic waves on a grid to wave-particle resonances, including aliased resonances, i.e., $\\omega + 2\\pi\\mu/\\Delta t=(k_1+ 2\\pi\

  16. On the physical origin of the generic instabilities present in linearized dissipative relativistic hydrodynamics

    CERN Document Server

    García-Perciante, A L; Sandoval-Villalbazo, A


    It is shown that the generic instabilities that appear in the framework of relativistic linear irreversible thermodynamics, describing the fluctuations of a simple fluid close to equilibrium, arise due to the inclusion of heat in the energy-momentum tensor that governs the fluid evolution. Further, it is also shown how such instabilities can be avoided within a relativistic linear framework if a Meixner-like approach to the phenomenological equations is employed.

  17. Assessment of Lateral Driving Stability of Automobiles Passing by the Pylon Zone under Cross Wind


    Dalei Wang; Airong Chen


    In order to explore the reason of lateral instability of automobile passing by the pylon zone of cablesupported bridge under cross wind, a new evaluation method of lateral driving stability of automobile considering alternative cross wind is established based on multi-objective driving stability criteria and subjective assessment. Typical driving control process and dynamic response of automobile passing by the pylon zone is given by numerical simulation based on steering wheel fixed-control ...

  18. Lateral Thinking and Technology Education. (United States)

    Waks, Shlomo


    Presents an analysis of technology education and its relevance to lateral thinking. Discusses prospects for utilizing technology education as a platform and a contextual domain for nurturing lateral thinking. Argues that technology education is an appropriate environment for developing complementary incorporation of vertical and lateral thinking.…

  19. [Cervical spine instability in the surgical patient]. (United States)

    Barbeito, A; Guerri-Guttenberg, R A


    Many congenital and acquired diseases, including trauma, may result in cervical spine instability. Given that airway management is closely related to the movement of the cervical spine, it is important that the anesthesiologist has detailed knowledge of the anatomy, the mechanisms of cervical spine instability, and of the effects that the different airway maneuvers have on the cervical spine. We first review the normal anatomy and biomechanics of the cervical spine in the context of airway management and the concept of cervical spine instability. In the second part, we review the protocols for the management of cervical spine instability in trauma victims and some of the airway management options for these patients.

  20. Two-Fluid Interface Instability Being Studied (United States)

    Niederhaus, Charles E.


    The interface between two fluids of different density can experience instability when gravity acts normal to the surface. The relatively well known Rayleigh-Taylor (RT) instability results when the gravity is constant with a heavy fluid over a light fluid. An impulsive acceleration applied to the fluids results in the Richtmyer-Meshkov (RM) instability. The RM instability occurs regardless of the relative orientation of the heavy and light fluids. In many systems, the passing of a shock wave through the interface provides the impulsive acceleration. Both the RT and RM instabilities result in mixing at the interface. These instabilities arise in a diverse array of circumstances, including supernovas, oceans, supersonic combustion, and inertial confinement fusion (ICF). The area with the greatest current interest in RT and RM instabilities is ICF, which is an attempt to produce fusion energy for nuclear reactors from BB-sized pellets of deuterium and tritium. In the ICF experiments conducted so far, RM and RT instabilities have prevented the generation of net-positive energy. The $4 billion National Ignition Facility at Lawrence Livermore National Laboratory is being constructed to study these instabilities and to attempt to achieve net-positive yield in an ICF experiment.

  1. Aeroelastic instability problems for wind turbines

    DEFF Research Database (Denmark)

    Hansen, Morten Hartvig


    This paper deals with the aeroelostic instabilities that have occurred and may still occur for modem commercial wind turbines: stall-induced vibrations for stall-turbines, and classical flutter for pitch-regulated turbines. A review of previous works is combined with derivations of analytical...... stiffness and chordwise position of the center of gravity along the blades are the main parameters for flutter. These instability characteristics are exemplified by aeroelastic stability analyses of different wind turbines. The review of each aeroelastic instability ends with a list of current research...... issues that represent unsolved aeroelostic instability problems for wind turbines. Copyright (c) 2007 John Wiley & Sons, Ltd....

  2. Review of two-phase instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Han Ok; Seo, Han Ok; Kang, Hyung Suk; Cho, Bong Hyun; Lee, Doo Jeong


    KAERI is carrying out a development of the design for a new type of integral reactors. The once-through helical steam generator is important design features. The study on designs and operating conditions which prevent flow instability should precede the introduction of one-through steam generator. Experiments are currently scheduled to understand two-phase instability, evaluate the effect of each design parameter on the critical point, and determine proper inlet throttling for the prevention of instability. This report covers general two-phase instability with review of existing studies on this topics. The general classification of two phase flow instability and the characteristics of each type of instability are first described. Special attention is paid to BWR core flow instability and once-through steam generator instability. The reactivity feedback and the effect of system parameters are treated mainly for BWR. With relation to once-through steam generators, the characteristics of convective heating and dryout point oscillation are first investigated and then the existing experimental studies are summarized. Finally chapter summarized the proposed correlations for instability boundary conditions. (author). 231 refs., 5 tabs., 47 figs

  3. Systems and methods for controlling flame instability

    KAUST Repository

    Cha, Min Suk


    A system (62) for controlling flame instability comprising: a nozzle (66) coupled to a fuel supply line (70), an insulation housing (74) coupled to the nozzle, a combustor (78) coupled to the nozzle via the insulation housing, where the combustor is grounded (80), a pressure sensor (82) coupled to the combustor and configured to detect pressure in the combustor, and an instability controlling assembly coupled to the pressure sensor and to an alternating current power supply (86), where, the instability controlling assembly can control flame instability of a flame in the system based on pressure detected by the pressure sensor.

  4. Instabilities of flows and transition to turbulence

    CERN Document Server

    Sengupta, Tapan K


    Introduction to Instability and TransitionIntroductionWhat Is Instability?Temporal and Spatial InstabilitySome Instability MechanismsComputing Transitional and Turbulent FlowsFluid Dynamical EquationsSome Equilibrium Solutions of the Basic EquationBoundary Layer TheoryControl Volume Analysis of Boundary LayersNumerical Solution of the Thin Shear Layer (TSL) EquationLaminar Mixing LayerPlane Laminar JetIssues of Computing Space-Time Dependent FlowsWave Interaction: Group Velocity and Energy FluxIssues of Space-Time Scale Resolution of FlowsTemporal Scales in Turbulent FlowsComputing Time-Averag

  5. The Chemistry of Beer Instability (United States)

    Stewart, Graham G.


    Compared to most other alcoholic beverages, beer is unique because it is unstable when in the final package. This instability can be divided into biological and nonbiological instability. Nonbiological stability of beer involves a wide range of chemical processes and can be considered in a number of categories: physical, flavor, light, foam, and gushing. It is the balance between flavanoid polyphenols (tannoids) and sensitive proteins that specifically combine with polyphenols to form haze that largely dictates physical stability. The flavor stability of beer primarily depends on the oxygen concentration of packaged beer but is influenced by all stages of the brewing process. Foam stability in a glass of beer reflects the quality of the beverage. The backbone of foam is hydrophobic polypeptides. Novel brewing processes such as high-gravity brewing result in a disproportionate loss of these polypeptides and have a negative effect on the foam stability of the resulting beer. Beer is light sensitive, especially in the 350 500 nm range. Beer exposed to this wavelength range in clear or green glass containers quickly develop nauseous skunky-like off-flavors resulting from the formation of 3-methyl-2-butene-1-thiol. Methods of enhancing all of these types of beer stability are discussed.

  6. Cosmic Rays and Radiative Instabilities

    CERN Document Server

    Hartquist, T W; Falle, S A E G; Pittard, J M; Van Loo, S


    In the absence of magnetic fields and cosmic rays, radiative cooling laws with a range of dependences on temperature affect the stability of interstellar gas. For about four and a half decades, astrophysicists have recognised the importance of the thermal instablity for the formation of clouds in the interstellar medium. Even in the past several years, many papers have concerned the role of the thermal instability in the production of molecular clouds. About three and a half decades ago, astrophysicists investigating radiative shocks noticed that for many cooling laws such shocks are unstable. Attempts to address the effects of cosmic rays on the stablity of radiative media that are initially uniform or that have just passed through shocks have been made. The simplest approach to such studies involves the assumption that the cosmic rays behave as a fluid. Work based on such an approach is described. Cosmic rays have no effect on the stability of initially uniform, static media with respect to isobaric perturb...

  7. Visco-Resistive Plasmoid Instability

    CERN Document Server

    Comisso, Luca


    The plasmoid instability in visco-resistive current sheets is analyzed in both the linear and nonlinear regimes. The linear growth rate and the wavenumber are found to scale as $S^{1/4} {\\left( {1 + {P_m}} \\right)}^{-5/8}$ and $S^{3/8} {\\left( {1 + {P_m}} \\right)}^{-3/16}$ with respect to the Lundquist number $S$ and the magnetic Prandtl number $P_m$. Furthermore, the linear layer width is shown to scale as $S^{-1/8} {(1+P_m)}^{1/16}$. The growth of the plasmoids slows down from an exponential growth to an algebraic growth when they enter into the nonlinear regime. In particular, the time-scale of the nonlinear growth of the plasmoids is found to be $\\tau_{NL} \\sim S^{-3/16} {(1 + P_m)^{19/32}}{\\tau _{A,L}}$. The nonlinear growth of the plasmoids is radically different from the linear one and it is shown to be essential to understand the global current sheet disruption. It is also discussed how the plasmoid instability enables fast magnetic reconnection in visco-resistive plasmas. In particular, it is shown t...

  8. Combustion instability modeling and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Santoro, R.J.; Yang, V.; Santavicca, D.A. [Pennsylvania State Univ., University Park, PA (United States)] [and others


    It is well known that the two key elements for achieving low emissions and high performance in a gas turbine combustor are to simultaneously establish (1) a lean combustion zone for maintaining low NO{sub x} emissions and (2) rapid mixing for good ignition and flame stability. However, these requirements, when coupled with the short combustor lengths used to limit the residence time for NO formation typical of advanced gas turbine combustors, can lead to problems regarding unburned hydrocarbons (UHC) and carbon monoxide (CO) emissions, as well as the occurrence of combustion instabilities. Clearly, the key to successful gas turbine development is based on understanding the effects of geometry and operating conditions on combustion instability, emissions (including UHC, CO and NO{sub x}) and performance. The concurrent development of suitable analytical and numerical models that are validated with experimental studies is important for achieving this objective. A major benefit of the present research will be to provide for the first time an experimentally verified model of emissions and performance of gas turbine combustors.

  9. Kelvin-Helmholtz Instability in the Solar Atmosphere, Solar Wind and Geomagnetosphere (United States)

    Mishin, V. V.; Tomozov, V. M.


    Modern views on the nature of the Kelvin-Helmholtz (KH) instability and its manifestations in the solar corona, in the interplanetary medium, and at the geomagnetospheric boundary are under consideration. We briefly describe the main theoretical results of the KH instability obtained in the linear approximation. Analysis of observational data, confirming the occurrence of the KH instability in magnetic formations of the solar coronal plasma and on the daytime magnetopause, was mainly performed in the approximation of incompressibility. We show that the Rayleigh-Taylor instability can significantly enhance the KH instability in the above regions due to interface accelerations or its curvature. Special attention is focused on the compressibility effect on the supersonic shear flow instability in the solar wind (SW) and at the geomagnetic tail boundary where this instability is usually considered to be ineffective. We have shown that the phase velocity of oblique perturbations is substantially less than the flow velocity, and values of the growth rate and frequency range are considerably higher than when only taking velocity-aligned disturbances into account. We emphasize that the magnetic field and plasma density inhomogeneity which weaken the KH instability of subsonic shear flows, in the case of a supersonic velocity difference weaken the stabilizing effect of the medium compressibility, and can significantly increase the instability. Effective generation of oblique disturbances by the supersonic KH instability explains the observations of magnetosonic waves and the formation of diffuse shear flows in the SW and on the distant magnetotail boundary, as well as the SW-magnetosphere energy and impulse transfer.

  10. Investigation of the vertical instability at the Argonne Intense Pulsed Neutron Source (United States)

    Wang, Shaoheng; Dooling, J. C.; Harkay, K. C.; Kustom, R. L.; McMichael, G. E.


    The rapid cycling synchrotron of the intense pulsed neutron source at Argonne National Laboratory normally operates at an average beam current of 14 to 15μA, accelerating protons from 50 to 450 MeV 30 times per second. The beam current is limited by a single-bunch vertical instability that occurs in the later part of the 14 ms acceleration cycle. By analyzing turn-by-turn beam position monitor data, two cases of vertical beam centroid oscillations were discovered. The oscillations start from the tail of the bunch, build up, and develop toward the head of the bunch. The development stops near the bunch center and oscillations remain localized in the tail for a relatively long time (2-4 ms, 1-2×104 turns). This vertical instability is identified as the cause of the beam loss. We compared this instability with a head-tail instability that was purposely induced by switching off sextupole magnets. It appears that the observed vertical instability is different from the classical head-tail instability.

  11. Amyotrophic lateral sclerosis: update

    Directory of Open Access Journals (Sweden)

    Zapata-Zapata, Carlos Hugo


    Full Text Available Amyotrophic lateral sclerosis is a neurodegenerative disease with devastating consequences for the patient and his/her family. Its etiology is still not clear. In about 10 % of the patients there is a hereditary pattern of the disease. Worldwide, prevalence ranges from 2 to 11 cases per 100,000 people. Age of presentation varies from 58 to 63 years for sporadic cases, and from 47 to 52 years for the familial ones. Concerning gender, there is a slight preference for males. Clinical manifestations include signs of upper and lower motor neurons, damage in limbs and bulbar muscles, and, in some patients, frontotemporal cognitive dysfunction. Diagnosis is essentially clinical supported by neurophysiological studies, such as needle electromyography, which is the most important test for early diagnosis. There is no cure, but riluzol has proven to delay the use of mechanical ventilation and to slightly prolong survival. Consequently, management is based on support measures, such as those related to nutrition and ventilatory function, in addition to control of the motor and non-motor symptoms of the disease.

  12. Extra-articular Mimickers of Lateral Meniscal Tears (United States)

    Barker, Joseph U.; Strauss, Eric J.; Lodha, Sameer; Bach, Bernard R.


    Context: Lateral meniscus tears are a common entity seen in sports medicine. Although lateral-side knee pain is often the result of a meniscus injury, several extra-articular pathologies share signs and symptoms with a meniscus tear. It is critical for the clinician to be able to identify and understand extra-articular pathologies that can present similar to a lateral meniscus tear. Evidence Acquisition: Data were collected through a thorough review of the literature conducted through a MEDLINE search for all relevant articles between 1980 and February 2010. Study Type: Clinical review. Results: Common extra-articular pathologies that can mimic lateral meniscal tears include iliotibial band syndrome, proximal tibiofibular joint instability, snapping biceps femoris or popliteus tendons, and peroneal nerve compression syndrome or neuritis. The patient history, physical examination features, and radiographic findings can be used to separate these entities from the more common intra-articular knee pathologies. Conclusions: In treating patients who present with lateral-sided knee pain, clinicians should be able to recognize and treat extra-articular pathologies that can present in a similar fashion as lateral meniscus tears. PMID:23015995

  13. Three-dimensional transfer of the tibial tuberosity for patellar instability with patella alta. (United States)

    Otsuki, Shuhei; Nakajima, Mikio; Oda, Shuhei; Hoshiyama, Yoshiaki; Fujiwara, Kenta; Jotoku, Tsuyoshi; Neo, Masashi


    Although patellar instability can be treated with several surgical procedures, the appropriate surgical treatment for patellar instability with patella alta has not yet been investigated. The objective of this study is to find out whether three-dimensional transfer of the tibial tuberosity elicits good knee functionality with improved patella alta and prevents further patellar dislocation. Twelve knees (10 patients) underwent surgery for patellar instability with patella alta from 2007 to 2011. The surgery performed was a three-dimensional transfer for the anteromedial distalization of the tibial tuberosity. Predisposing anatomical factors for patellar instability were evaluated preoperatively; femorotibial angle (FTA), patella alta (IS ratio), trochlear dysplasia (sulcus angle) and tilting angle (lateral tilt). The function of the knee was assessed before and after surgery by Lysholm and Kujala score. Before surgery, the IS ratio was 1.34 ± 0.13, lateral tilt was 22.4° ± 6.5°, and the sulcus angle was 151.7° ± 8.3°, indicating patella alta, laterality, and trochlear dysplasia. After surgery, the IS ratio and lateral tilt significantly improved to 0.95 ± 0.13, and 10.6° ± 3.4°, respectively. FTA and sulcus angle were not altered. Lysholm and Kujala score improved from 63.8 to 94.7 and 67.0 to 94.1 points, respectively. Most patients displayed good outcomes except for one patient who suffered re-dislocation by hitting their knee on the floor, 2.5 years after surgery. Three-dimensional tibial tuberosity transfer was shown to correct the patella position and result in a good clinical outcome. This method is introduced as an alternative surgery for patellar instability with patella alta.

  14. Design guidelines for passive instability suppression - Task-11 report[Wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, M.H.; Buhl, T.


    rotor has an influence on the aerodynamic damping of the turbine mode due to the dynamic behavior of the induced velocities from the wake. When the turbine is operating with an yaw error, a small change in the aerodynamic damping of lower damped turbine modes is observed that may be caused by change of wake geometry. 8. Effect of generator dynamics: The total damping of turbine modes involving drive train rotation, as the drive train torsion and lateral tower modes, are highly affected by the dynamic behavior of the generator torque. The aeroelastic damping of these modes changes if the generator is operated at constant speed (e.g. asynchronous generators), constant torque, or constant power (e.g. double-fed induction machines). (au)

  15. Antecedent disease and Amyotrophic Lateral Sclerosis: What is protecting whom?

    Directory of Open Access Journals (Sweden)

    Sabrina K Hollinger


    . Pathological homeostatic instability exacerbated by hypervigilant regulation (over-zealous homeostatic regulation due to too-high regulatory feedback gains is a viable hypothesis for explaining the early-life protection against antecedent disease and the overall lower antecedent disease prevalence in ALS patients; the later ALS onset age in patients with antecedent disease; and the inverse relationship between ALS onset age and disease duration.

  16. Diamond heteroepitaxial lateral overgrowth (United States)

    Tang, Yung-Hsiu

    This dissertation describes improvements in the growth of single crystal diamond by microwave plasma-assisted chemical vapor deposition (CVD). Heteroepitaxial (001) diamond was grown on 1 cm. 2 a-plane sapphiresubstrates using an epitaxial (001) Ir thin-film as a buffer layer. Low-energy ion bombardment of the Ir layer, a process known as bias-enhanced nucleation, is a key step in achieving a high density of diamond nuclei. Bias conditions were optimized to form uniformly-high nucleation densities across the substrates, which led to well-coalesced diamond thin films after short growth times. Epitaxial lateral overgrowth (ELO) was used as a means of decreasing diamond internal stress by impeding the propagation of threading dislocations into the growing material. Its use in diamond growth requires adaptation to the aggressive chemical and thermal environment of the hydrogen plasma in a CVD reactor. Three ELO variants were developed. The most successful utilized a gold (Au) mask prepared by vacuum evaporation onto the surface of a thin heteroepitaxial diamond layer. The Au mask pattern, a series of parallel stripes on the micrometer scale, was produced by standard lift-off photolithography. When diamond overgrows the mask, dislocations are largely confined to the substrate. Differing degrees of confinement were studied by varying the stripe geometry and orientation. Significant improvement in diamond quality was found in the overgrown regions, as evidenced by reduction of the Raman scattering linewidth. The Au layer was found to remain intact during diamond overgrowth and did not chemically bond with the diamond surface. Besides impeding the propagation of threading dislocations, it was discovered that the thermally-induced stress in the CVD diamond was significantly reduced as a result of the ductile Au layer. Cracking and delamination of the diamond from the substrate was mostly eliminated. When diamond was grown to thicknesses above 0.1 mm it was found that

  17. Electro-convective versus electroosmotic instability in concentration polarization. (United States)

    Rubinstein, Isaak; Zaltzman, Boris


    Electro-convection is reviewed as a mechanism of mixing in the diffusion layer of a strong electrolyte adjacent to a charge-selective solid, such as an ion exchange (electrodialysis) membrane or an electrode. Two types of electro-convection in strong electrolytes may be distinguished: bulk electro-convection, due to the action of the electric field upon the residual space charge of a quasi-electro-neutral bulk solution, and convection induced by electroosmotic slip, due to electric forces acting in the thin electric double layer of either quasi-equilibrium or non-equilibrium type near the solid/liquid interface. According to recent studies, the latter appears to be the likely source of mixing in the diffusion layer, leading to 'over-limiting' conductance in electrodialysis. Electro-convection near a planar uniform charge selective solid/liquid interface sets on as a result of hydrodynamic instability of one-dimensional steady state electric conduction through such an interface. We compare the results of linear stability analysis obtained for instabilities of this kind appearing in the full electro-convective and limiting non-equilibrium electroosmotic formulations. The short- and long-wave aspects of these instabilities are discussed along with the wave number selection principles.

  18. Ectopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic Instability

    Directory of Open Access Journals (Sweden)

    Aaraby Yoheswaran Nielsen


    Full Text Available Genomic instability is a hallmark of human cancer and an enabling factor for the genetic alterations that drive cancer development. The processes involved in genomic instability resemble those of meiosis, where genetic material is interchanged between homologous chromosomes. In most types of human cancer, epigenetic changes, including hypomethylation of gene promoters, lead to the ectopic expression of a large number of proteins normally restricted to the germ cells of the testis. Due to the similarities between meiosis and genomic instability, it has been proposed that activation of meiotic programs may drive genomic instability in cancer cells. Some germ cell proteins with ectopic expression in cancer cells indeed seem to promote genomic instability, while others reduce polyploidy and maintain mitotic fidelity. Furthermore, oncogenic germ cell proteins may indirectly contribute to genomic instability through induction of replication stress, similar to classic oncogenes. Thus, current evidence suggests that testis germ cell proteins are implicated in cancer development by regulating genomic instability during tumorigenesis, and these proteins therefore represent promising targets for novel therapeutic strategies.

  19. Knee motion variability in patients with knee osteoarthritis: the effect of self-reported instability (United States)

    Gustafson, Jonathan A.; Robinson, Megan E.; Fitzgerald, G. Kelley; Tashman, Scott; Farrokhi, Shawn


    Background Knee osteoarthritis has been previously associated with a stereotypical knee-stiffening gait pattern and reduced knee joint motion variability due to increased antagonist muscle co-contractions and smaller utilized arc of motion during gait. However, episodic self-reported instability may be a sign of excessive motion variability for a large subgroup of patients with knee osteoarthritis. The objective of this work was to evaluate the differences in knee joint motion variability during gait in patients with knee osteoarthritis with and without self-reported instability compared to a control group of older adults with asymptomatic knees. Methods Forty-three subjects, 8 with knee osteoarthritis but no reports of instability (stable), 11 with knee osteoarthritis and self-reported instability (unstable), and 24 without knee osteoarthritis or instability (control) underwent Dynamic Stereo X-ray analysis during a decline gait task on a treadmill. Knee motion variability was assessed using parametric phase plots during the loading response phase of decline gait. Findings The stable group demonstrated decreased sagittal-plane motion variability compared to the control group (p=0.04), while the unstable group demonstrated increased sagittal-plane motion variability compared to the control (p=0.003) and stable groups (pknee motion variability in patients with knee osteoarthritis without self-reported instability supports previous research. However, presence of self-reported instability is associated with increased knee motion variability in patients with knee osteoarthritis and warrants further investigation. PMID:25796536

  20. On the descriptions of beam instabilities

    CERN Document Server

    Maillard, Antoine


    We investigate two interesting features of beam instabilities in accelerators : First, we provide the equivalence between two models to describe transverse instabilities, the circulant matrix model (based on a longitudinal phase space discretization) and the Vlasov formalism. Secondly, we show how to derive dispersion integrals for transverse detuning effects in the Vlasov formalism, thus allowing for Landau damping mechanism.

  1. Parametric Instability: An Elementary Demonstration and Discussion. (United States)

    Case, William


    Discusses parametric oscillators and parametric instability. A simple, easy-to-construct system which exhibits parametric instability is presented. The two lowest-order resonances are described and analyzed in detail. The analysis stresses the physical and intuitive aspects of the problem. (Author/HM)

  2. Energetic particle instabilities in fusion plasmas

    NARCIS (Netherlands)

    Sharapov, S. E.; Alper, B.; Berk, H. L.; Borba, D. N.; Breizman, B. N.; Challis, C. D.; Classen, I.G.J.; Edlund, E. M.; Eriksson, J.; Fasoli, A.; Fredrickson, E. D.; Fu, G. Y.; Garcia-Munoz, M.; Gassner, T.; Ghantous, K.; Goloborodko, V.; Gorelenkov, N. N.; Gryaznevich, M. P.; Hacquin, S.; Heidbrink, W. W.; Hellesen, C.; Kiptily, V. G.; Kramer, G. J.; Lauber, P.; Lilley, M. K.; Lisak, M.; Nabais, F.; Nazikian, R.; Nyqvist, R.; Osakabe, M.; C. Perez von Thun,; Pinches, S. D.; Podesta, M.; Porkolab, M.; Shinohara, K.; Schoepf, K.; Todo, Y.; Toi, K.; VanZeeland, M. A.; Voitsekhovich, I.; White, R. B.; Yavorskij, V.; ITPA EP TG Contributors,; JET-EFDA Contributors,


    Remarkable progress has been made in diagnosing energetic particle instabilities on present-day machines and in establishing a theoretical framework for describing them. This overview describes the much improved diagnostics of Alfvén instabilities and modelling tools developed world-wide, and discus

  3. Cultural diversity, economic development and societal instability (United States)

    Nettle, D.; Grace, J.B.; Choisy, M.; Cornell, H.V.; Guegan, J.-F.; Hochberg, M.E.


    Background. Social scientists have suggested that cultural diversity in a nation leads to societal instability. However, societal instability may be affected not only by within-nation on ?? diversity, but also diversity between a nation and its neighbours or ?? diversity. It is also necessary to distinguish different domains of diversity, namely linguistic, ethnic and religious, and to distinguish between the direct effects of diversity on societal instability, and effects that are mediated by economic conditions. Methodology/Principal Findings. We assembled a large cross-national dataset with information on ?? and ?? cultural diversity, economic conditions, and indices of societal instability. Structural equation modeling was used to evaluate the direct and indirect effects of cultural diversity on economics and societal stability. Results show that different type and domains of diversity have interacting effects. As previously documented, linguistic ?? diversity has a negative effect on economic performance, and we show that it is largely through this economic mechanism that it affects societal instability. For ?? diversity, the higher the linguistic diversity among nations in a region, the less stable the nation. But, religious ?? diversity has the opposite effect, reducing instability, particularly in the presence of high linguistic diversity. Conclusions. Within-nation linguistic diversity is associated with reduced economic performance, which, in turn, increases societal instability. Nations which differ linguistically from their neighbors are also less stable. However, religious diversity between, neighboring nations has the opposite effect, decreasing societal instability.

  4. Magnetic resonance imaging in glenohumeral instability (United States)

    Jana, Manisha; Gamanagatti, Shivanand


    The glenohumeral joint is the most commonly dislocated joint of the body and anterior instability is the most common type of shoulder instability. Magnetic resonance (MR) imaging, and more recently, MR arthrography, have become the essential investigation modalities of glenohumeral instability, especially for pre-procedure evaluation before arthroscopic surgery. Injuries associated with glenohumeral instability are variable, and can involve the bones, the labor-ligamentous components, or the rotator cuff. Anterior instability is associated with injuries of the anterior labrum and the anterior band of the inferior glenohumeral ligament, in the form of Bankart lesion and its variants; whereas posterior instability is associated with reverse Bankart and reverse Hill-Sachs lesion. Multidirectional instability often has no labral pathology on imaging but shows specific osseous changes such as increased chondrolabral retroversion. This article reviews the relevant anatomy in brief, the MR imaging technique and the arthrographic technique, and describes the MR findings in each type of instability as well as common imaging pitfalls. PMID:22007285

  5. Hydrodynamic Instabilities in Rotating Fluids

    Institute of Scientific and Technical Information of China (English)



    Rotating flow systems are often used to study stability phenomena and structure developments.The closed spherical gap prblem is generalized into an open flow system by superimposing a mass flux in meridional direction.The basic solutions at low Reynolds numbers are described by analytical methods.The nonlinear supercritical solutions are simulated numerically and realized in experiments.Novel steady and time-dependent modes of flows are obtained.The extensive results concern the stability behaviour.non-uniqueness of supercritical solutions,symmetry behaviour and transitions between steady and time-dependent solutions.The experimental investigations concern the visualization of the various instabilities and the quatitative description of the flow structures including the laminar-turbulent transition.A Comparison between theoretical and experimental results shows good agreement within the limit of rotational symmetric solutions from the theory.

  6. Transient spirals as superposed instabilities

    CERN Document Server

    Sellwood, J A


    We present evidence that recurrent spiral activity, long manifested in simulations of disk galaxies, results from the super-position of a few transient spiral modes. Each mode lasts between five and ten rotations at its corotation radius where its amplitude is greatest. The scattering of stars as each wave decays takes place over narrow ranges of angular momentum, causing abrupt changes to the impedance of the disk to subsequent traveling waves. Partial reflections of waves at these newly created features, allows new standing-wave instabilities to appear that saturate and decay in their turn, scattering particles at new locations, creating a recurring cycle. The spiral activity causes the general level of random motion to rise, gradually decreasing the ability of the disk to support further activity unless the disk contains a dissipative gas component from which stars form on near-circular orbits. We also show that this interpretation is consistent with the behavior reported in other recent simulations with l...

  7. Gravitational Instability of a Kink

    CERN Document Server

    Barreto, W; Lehner, L; Winicour, J


    We study the equilibria of a self-gravitating scalar field in the region outside a reflecting barrier. By introducing a potential difference between the barrier and infinity, we create a kink which cannot decay to a zero energy state. In the realm of small amplitude, the kink decays to a known static solution of the Einstein-Klein-Gordon equation. However, for larger kinks the static equilibria are degenerate, forming a system with two energy levels. The upper level is unstable and, under small perturbations, decays to the lower energy stable equilibrium. Under large perturbations, the unstable upper level undergoes collapse to a black hole. The equilibrium of the system provides a remarkably simple and beautiful illustration of a turning point instability.

  8. Mapping Instabilities in Polymer Friction (United States)

    Rand, Charles; Crosby, Alfred


    Schallamach waves are instabilities that occur as interfaces between a soft elastomer and rigid surface slide past each other.(1) The presence of Schallamach waves can lead to drastic changes in frictional properties. Although the occurrence of Schallamach waves has been studied for the past several decades, a general map relating fundamental material properties, geometry, and operating conditions (i.e. speed and temperature) has not been established. Using a combinatorial approach, we illustrate the role of modulus, testing velocity and surface energetics of crosslinked poly(dimethyl siloxane) on the generation Schallamach waves. This knowledge will be used with polymer patterning processes to fabricate responsive coatings for applications such as anti-fouling coatings. (1)Schallamach, A.;Wear 1971,17, 301-312.

  9. Longitudinal Coupled-Bunch Instabilities in the CERN PS

    CERN Document Server

    Damerau, H; Mehler, M; Rossi, C; Shaposhnikova, E; Tückmantel, Joachim; Vallet, J L


    Longitudinal coupled bunch instabilities in the CERN PS represent a major limitation to the high brightness beam delivered for the LHC. To identify possible impedance sources for these instabilities, machine development studies have been carried out. The growth rates of coupled bunch modes have been measured, and modes have been identified using mountain range data. Growth rate estimations from coupled bunch mode theory are compared to these results. It is shown that the longitudinal impedance of the broad resonance curve of the main 10 MHz RF system can be identified as the most probable source. Several modes are driven simultaneously due to the large width of the resonance, which is considered for the analysis.

  10. Resonant Dampers for Parametric Instabilities in Gravitational Wave Detectors

    CERN Document Server

    Gras, Slawek; Barsotti, Lisa; Evans, Matthew


    Advanced gravitational wave interferometric detectors will operate at their design sensitivity with nearly 1MW of laser power stored in the arm cavities. Such large power may lead to the uncontrolled growth of acoustic modes in the test masses due to the transfer of optical energy to the mechanical modes of the arm cavity mirrors. These parametric instabilities have the potential of significantly compromising the detector performance and control. Here we present the design of "acoustic mode dampers" that use the piezoelectric effect to reduce the coupling of optical to mechanical energy. Experimental measurements carried on an Advanced LIGO-like test mass shown a 10-fold reduction in the amplitude of several mechanical modes, thus suggesting that this technique can greatly mitigate the impact of parametric instabilities in advanced detectors.

  11. Estimates of CSR Instability Thresholds for Various Storage Rings

    CERN Document Server

    Zimmermann, Frank


    We review the key predictions and conditions by several authors for the onset of longitudinal instabilities due to coherent synchrotron radiation (CSR), and evaluate them numerically for various storage rings, namely the KEKB High Energy Ring (HER) & Low Energy Ring (LER), SuperKEKB HER & LER, old and new designs of the SuperKEKB Damping Ring (DR), SuperB HER & LER, CLIC DR (2009 and 2010 design parameters), SLC DR, and ATF DR. We show that the theoretical uncertainty in the instability onset is at least at the level of 20-30% in bunch intensity. More importantly, we present some doubts about the general applicability for many of these storage rings of some commonly used formulae. To cast further light on these questions, an experiment at lower beam energy on the ATF Damping Ring is proposed.

  12. Dispersion-Induced Beam Instability in Circular Accelerators (United States)

    Yuan, Y. S.; Boine-Frankenheim, O.; Franchetti, G.; Hofmann, I.


    The envelope instability near the 90° phase advance in periodically focused space charge dominated beams is a well-known phenomenon in linear transport sections or linacs. The corresponding stop band is usually avoided because of the resulting strong mismatch oscillations and beam loss. We show that in circular accelerators or transport sections including bending magnets the instability is modified due to the effect of dispersion. Using the two-dimensional envelope equations extended by the dispersion equation we identify an additional stop band above 120°. For periodic focusing the stop band results from the confluence of an envelope mode with the newly identified coherent dispersion mode. Results from perturbation theory are compared with the full envelope model and particle-in-cell simulation, which all show good agreement. The newly identified mode has several implications and applications for the characterization of intense beams in circular machines.

  13. Detonation initiation developing from the Richtmyer-Meshkov instability

    Institute of Scientific and Technical Information of China (English)

    H.H.Teng; Z.L.Jiang; Z.M.Hu


    Detonation initiation resulting from theRichtmyer-Meshkov instability is investigated numericallyin the configuration of the shock/spark-induced-deflagrationinteraction in a combustive gas mixture. Two-dimensionalmulti-species Navier-Stokes equations implemented with thedetailed chemical reaction model are solved with thedispersion-controlled dissipative scheme. Numerical resultsshow that the spark can create a blast wave and ignite defla-grations. Then, the deflagration waves are enhanced due tothe Richtmyer-Meshkov instability, which provides detona-tion initiations with local environment conditions. Byexamining the deflagration fronts, two kinds of the initiationmechanisms are identified. One is referred to as the deflagra-tion front acceleration with the help of the weak shock wave,occurring on the convex surfaces, and the other is the hotspot explosion deriving from the deflagration front focusing,occurring on the concave surfaces.

  14. Effects of Fluid Instabilities on Accretion Disk Spectra

    CERN Document Server

    Davis, S W; Turner, N J; Socrates, A


    Numerical calculations and linear theory of radiation magnetohydrodynamic flows indicate that the photon bubble and magnetorotational instability (MRI) may produce large density inhomogeneities in radiation pressure supported media. We study the effects of the photon bubble instability on accretion disk spectra using 2-D Monte Carlo (MC) and 1-D Feautrier radiative transfer calculations on a snapshot of a 2-D numerical simulation domain. We find an enhancement in the thermalization of the MC spectra over that of the Feautrier calculation. In the inner-most regions of these disks, the turbulent magnetic pressure may greatly exceed that of the gas. It is then possible for bulk turbulent Alfvenic motions driven by the MRI to exceed the thermal velocity making turbulent Comptonization the dominant radiative process. We estimate the spectral distortion due to turbulent Comptonization utilizing a 1-D MC calculation.

  15. Quasimonomorphic Mononucleotide Repeats for High-Level Microsatellite Instability Analysis

    Directory of Open Access Journals (Sweden)

    Olivier Buhard


    Full Text Available Microsatellite instability (MSI analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non-Polyposis Colorectal Cancer (HNPCC cases. After some years of conflicting data due to the absence of consensus markers for the MSI phenotype, a meeting held in Bethesda to clarify the situation proposed a set of 5 microsatellites (2 mononucleotide repeats and 3 dinucleotide repeats to determine MSI tumors. A second Bethesda consensus meeting was held at the end of 2002. It was discussed here that the 1998 microsatellite panel could underestimate high-level MSI tumors and overestimate low-level MSI tumors. Amongst the suggested changes was the exclusive use of mononucleotide repeats in place of dinucleotide repeats. We have already proposed a pentaplex MSI screening test comprising 5 quasimonomorphic mononucleotide repeats. This article compares the advantages of mono or dinucleotide repeats in determining microsatellite instability.

  16. Emission from Pair-Instability Supernovae with Rotation

    CERN Document Server

    Chatzopoulos, Emmanouil; Wheeler, J Craig; Whalen, Daniel J; Smidt, Joseph; Wiggins, Brandon


    Pair Instability Supernovae have been suggested as candidates for some Super Luminous Supernovae, such as SN 2007bi, and as one of the dominant types of explosion occurring in the early Universe from massive, zero-metallicity Population III stars. The progenitors of such events can be rapidly rotating, therefore exhibiting different evolutionary properties due to the effects of rotationally-induced mixing and mass-loss. Proper identification of such events requires rigorous radiation hydrodynamics and radiative transfer calculations that capture not only the behavior of the light curve but also the spectral evolution of these events. We present radiation hydrodynamics and radiation transport calculations for 90-300 Msun rotating pair-instability supernovae covering both the shock break-out and late light curve phases. We also investigate cases of different initial metallicity and rotation rate to determine the impact of these parameters on the detailed spectral characteristics of these events. In agreement wi...

  17. Laplace-Fourier analysis and instabilities of a gainy slab

    CERN Document Server

    Hågenvik, Hans Olaf


    The idealization of monochromatic plane waves leads to considerable simplifications in the analysis of electromagnetic systems. However, for active systems this idealization may be dangerous due to the presence of growing waves. Here we consider a gainy slab, and use a realistic incident beam, which is both causal and has finite width. This clarifies some apparent paradoxes arising from earlier analyses of this setup. In general it turns out to be necessary to involve complex frequencies $\\omega$ and/or complex transversal wavenumbers $k_x$. Simultaneously real $\\omega$ and $k_x$ cannot describe amplified waves in a slab which is infinite in the transversal direction. We also show that the only possibility to have an absolute instability for a finite width beam, is if a normally incident plane wave would experience an instability.

  18. Weibel instability in a plasma with nonzero external magnetic field

    Directory of Open Access Journals (Sweden)

    O. A. Pokhotelov


    Full Text Available The theory of the Weibel instability is generalized for the case of a plasma immersed in a nonzero external magnetic field. It is shown that the presence of this external field modifies the dispersion relation for this mode which now possesses a nonzero frequency. The explicit expression for the real and imaginary parts of the frequency is then calculated. It turns out that the linear growth rate remains unchanged, whereas the frequency becomes nonzero due to the finite value of the electron cyclotron frequency. The frequency of the Weibel mode is found to be proportional to the electron temperature anisotropy. The formal similarity of the Weibel and drift-mirror instabilities is outlined.

  19. Active control of magneto-hydrodynamic instabilities in hot plasmas

    CERN Document Server


    During the past century, world-wide energy consumption has risen dramatically, which leads to a quest for new energy sources. Fusion of hydrogen atoms in hot plasmas is an attractive approach to solve the energy problem, with abundant fuel, inherent safety and no long-lived radioactivity.  However, one of the limits on plasma performance is due to the various classes of magneto-hydrodynamic instabilities that may occur. The physics and control of these instabilities in modern magnetic confinement fusion devices is the subject of this book. Written by foremost experts, the contributions will provide valuable reference and up-to-date research reviews for "old hands" and newcomers alike.


    Directory of Open Access Journals (Sweden)

    Moira Yip


    Full Text Available When laterals are the targets of phonological processes, laterality may or may not survive. In a fixed feature geometry, [lateral] should be lost if its superordinate node is eliminated by either the spreading of a neighbouring node, or by coda neutralization. So if [lateral] is under Coronal (Blevins 1994, it should be lost under Place assimilation, and if [lateral] is under Sonorant Voicing (Rice & Avery 1991 it should be lost by rules that spread voicing. Yet in some languages lateral survives such spreading intact. Facts like these argue against a universal attachment of [lateral] under either Coronal or Sonorant Voicing, and in favour of an account in terms of markedness constraints on feature-co-occurrence (Padgett 2000. The core of an OT account is that IFIDENTLAT is ranked above whatever causes neutralization, such as SHARE-F or *CODAF. laterality will survive. If these rankings are reversed, we derive languages in which laterality is lost. The other significant factor is markedness. High-ranked feature co-occurrence constraints like *LATDORSAL can block spreading from affecting laterals at all.

  1. Penetration and lateral diffusion characteristics of polycrystalline graphene barriers (United States)

    Yoon, Taeshik; Mun, Jeong Hun; Cho, Byung Jin; Kim, Taek-Soo


    We report penetration and lateral diffusion behavior of environmental molecules on synthesized polycrystalline graphene. Penetration occurs through graphene grain boundaries resulting in local oxidation. However, when the penetrated molecules diffuse laterally, the oxidation region will expand. Therefore, we measured the lateral diffusion rate along the graphene-copper interface for the first time by the environment-assisted crack growth test. It is clearly shown that the lateral diffusion is suppressed due to the high van der Waals interaction. Finally, we employed bilayer graphene for a perfect diffusion barrier facilitated by decreased defect density and increased lateral diffusion path.We report penetration and lateral diffusion behavior of environmental molecules on synthesized polycrystalline graphene. Penetration occurs through graphene grain boundaries resulting in local oxidation. However, when the penetrated molecules diffuse laterally, the oxidation region will expand. Therefore, we measured the lateral diffusion rate along the graphene-copper interface for the first time by the environment-assisted crack growth test. It is clearly shown that the lateral diffusion is suppressed due to the high van der Waals interaction. Finally, we employed bilayer graphene for a perfect diffusion barrier facilitated by decreased defect density and increased lateral diffusion path. Electronic supplementary information (ESI) available. See DOI: 10.1039/c3nr03849a

  2. The influence of sex hormones on brain lateralization : Research Programme

    NARCIS (Netherlands)

    Beking, Tess; Geuze, Reint; Groothuis, Antonius


    Between and within sexes individuals differ in lateralization of brain and behaviour that might affect cognitive performance. There is long standing debate to what extent variation in lateralization is due to variation in early or late exposure to sex hormones. We will use two unique data sets to te

  3. Non-linear analytical solutions for laterally loaded sandwich plates

    DEFF Research Database (Denmark)

    Riber, Hans Jørgen


    This work focuses on the response of orthotropic sandwich composite plates with large deflections due to high lateral loads. The results have special application to the design of ship structures. A geometrical nonlinear theory is outlined, on the basis of the classical sandwich plate theory...... of sandwich plates subjected to high lateral loading. (C) 1997 Published by Elsevier Science Ltd. All rights reserved....

  4. Lateral convection and diffusion of sediment in straight rivers

    DEFF Research Database (Denmark)

    Christensen, Henrik Bo; Fredsøe, Jørgen


    The lateral transport of suspended sediment in a straight river cross section with a parabolic shaped bed is studied be use of a k-e and a full Reynolds stress turbulence model. Due to depth variations a lateral transport of suspended sediment is generated. This is mainly caused by the slopping bed...

  5. Secondary instability in boundary-layer flows (United States)

    Nayfeh, A. H.; Bozatli, A. N.


    The stability of a secondary Tollmien-Schlichting wave, whose wavenumber and frequency are nearly one half those of a fundamental Tollmien-Schlichting instability wave is analyzed using the method of multiple scales. Under these conditions, the fundamental wave acts as a parametric exciter for the secondary wave. The results show that the amplitude of the fundamental wave must exceed a critical value to trigger this parametric instability. This value is proportional to a detuning parameter which is the real part of k - 2K, where k and K are the wavenumbers of the fundamental and its subharmonic, respectively. For Blasius flow, the critical amplitude is approximately 29% of the mean flow, and hence many other secondary instabilities take place before this parametric instability becomes significant. For other flows where the detuning parameter is small, such as free-shear layer flows, the critical amplitude can be small, thus the parametric instability might play a greater role.

  6. Taylor instability in rhyolite lava flows (United States)

    Baum, B. A.; Krantz, W. B.; Fink, J. H.; Dickinson, R. E.


    A refined Taylor instability model is developed to describe the surface morphology of rhyolite lava flows. The effect of the downslope flow of the lava on the structures resulting from the Taylor instability mechanism is considered. Squire's (1933) transformation is developed for this flow in order to extend the results to three-dimensional modes. This permits assessing why ridges thought to arise from the Taylor instability mechanism are preferentially oriented transverse to the direction of lava flow. Measured diapir and ridge spacings for the Little and Big Glass Mountain rhyolite flows in northern California are used in conjunction with the model in order to explore the implications of the Taylor instability for flow emplacement. The model suggests additional lava flow features that can be measured in order to test whether the Taylor instability mechanism has influenced the flows surface morphology.

  7. Whipping Instabilities in Electrified Liquid Jets

    CERN Document Server

    Marin, Alvaro G; Loscertales, Ignacio G; Barrero, Antonio


    A liquid jet may develop different types of instabilities, like the so-called Rayleigh-Plateau instability, which breaks the jet into droplets. However, another type of instabilities may appear when we electrify a liquid jet and induce some charge at his surface. Among them, the most common is the so-called Whipping Instability, which is characterized by violent and fast lashes of the jet. In the submitted fluid dynamic video(see, we will show an unstable charged glycerine jet in a dielectric liquid bath, which permits an enhanced visualization of the instability. For this reason, it is probably the first time that these phenomena are visualized with enough clarity to analyze features as the effect of the feeding liquid flow rate through the jet or as the surprising spontaneous stabilization at some critical distance to the ground electrode.

  8. 3-D nonlinear evolution of MHD instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Bateman, G.; Hicks, H. R.; Wooten, J. W.


    The nonlinear evolution of ideal MHD internal instabilities is investigated in straight cylindrical geometry by means of a 3-D initial-value computer code. These instabilities are characterized by pairs of velocity vortex cells rolling off each other and helically twisted down the plasma column. The cells persist until the poloidal velocity saturates at a few tenths of the Alfven velocity. The nonlinear phase is characterized by convection around these essentially fixed vortex cells. For example, the initially centrally peaked temperature profile is convected out and around to form an annulus of high temperature surrounding a small region of lower temperature. Weak, centrally localized instabilities do not alter the edge of the plasma. Strong, large-scale instabilities, resulting from a stronger longitudinal equilibrium current, drive the plasma against the wall. After three examples of instability are analyzed in detail, the numerical methods and their verification are discussed.

  9. Tensile Instability in a Thick Elastic Body (United States)

    Overvelde, Johannes T. B.; Dykstra, David M. J.; de Rooij, Rijk; Weaver, James; Bertoldi, Katia


    A range of instabilities can occur in soft bodies that undergo large deformation. While most of them arise under compressive forces, it has previously been shown analytically that a tensile instability can occur in an elastic block subjected to equitriaxial tension. Guided by this result, we conducted centimeter-scale experiments on thick elastomeric samples under generalized plane strain conditions and observed for the first time this elastic tensile instability. We found that equibiaxial stretching leads to the formation of a wavy pattern, as regions of the sample alternatively flatten and extend in the out-of-plane direction. Our work uncovers a new type of instability that can be triggered in elastic bodies, enlarging the design space for smart structures that harness instabilities to enhance their functionality.

  10. Lateral stepping for postural correction in Parkinson's disease. (United States)

    King, Laurie A; Horak, Fay B


    To characterize the lateral stepping strategies for postural correction in patients with Parkinson's disease (PD) and the effect of their anti-parkinson medication. Observational study. Outpatient neuroscience laboratory. Thirteen participants with idiopathic PD in their on (PD on) and off (PD off) levodopa state and 14 healthy elderly controls. Movable platform with lateral translations of 12 cm at 14.6 cm/s ramp velocity. The incidence and characteristics of 3 postural strategies were observed: lateral side-step, crossover step, or no step. Corrective stepping was characterized by latency to step after perturbation onset, step velocity, and step length and presence of an anticipatory postural adjustment (APA). Additionally, percentages of trials resulting in falls were identified for each group. Whereas elderly control participants never fell, PD participants fell in 24% and 35% of trials in the on and off medication states, respectively. Both PD and control participants most often used a lateral side-step strategy; 70% (control), 67% (PD off), and 73% (PD on) of all trials, respectively. PD participants fell most often when using a crossover strategy (75% of all crossover trials) or no-step strategy (100% of all no-step trials). In the off medication state, PD participants' lateral stepping strategies were initiated later than controls (370+/-37 ms vs 280+/-10 ms, Pcorrective stepping characteristics. Unlike control participants, PD participants often (56% of side-step strategy trials) failed to activate an APA before stepping, although their APAs, when present, were of similar latency and magnitude as for control participants. Levodopa on or off state did not significantly affect falls, APAs, or lateral step latency, velocity, or amplitude (P>.05). PD participants showed significantly more postural instability and falls than age-matched controls when stepping was required for postural correction in response to lateral disequilibrium. Although PD participants

  11. On the Numerical Dispersion of Electromagnetic Particle-In-Cell Code : Finite Grid Instability

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, Michael David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Univ. of California, Los Angeles, CA (United States) Dept. of Physics and Astronomy; Huang, Chengkun [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Zeng, Yong [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Yi, Sunghwan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Albright, Brian James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    The Particle-In-Cell (PIC) method is widely used in relativistic particle beam and laser plasma modeling. However, the PIC method exhibits numerical instabilities that can render unphysical simulation results or even destroy the simulation. For electromagnetic relativistic beam and plasma modeling, the most relevant numerical instabilities are the finite grid instability and the numerical Cherenkov instability. We review the numerical dispersion relation of the electromagnetic PIC algorithm to analyze the origin of these instabilities. We rigorously derive the faithful 3D numerical dispersion of the PIC algorithm, and then specialize to the Yee FDTD scheme. In particular, we account for the manner in which the PIC algorithm updates and samples the fields and distribution function. Temporal and spatial phase factors from solving Maxwell's equations on the Yee grid with the leapfrog scheme are also explicitly accounted for. Numerical solutions to the electrostatic-like modes in the 1D dispersion relation for a cold drifting plasma are obtained for parameters of interest. In the succeeding analysis, we investigate how the finite grid instability arises from the interaction of the numerical 1D modes admitted in the system and their aliases. The most significant interaction is due critically to the correct representation of the operators in the dispersion relation. We obtain a simple analytic expression for the peak growth rate due to this interaction.

  12. Evolution of Wake Instabilities and the Acceleration of the Slow Solar Wind: Melon Seed and Expansion Effects (United States)

    Rappazzo, A. F.; Velli, M.; Einaudi, G.; Dahlburg, R. B.


    We extend previous 2D simulation studies of slow solar wind acceleration due to the nonlinear evolution of the instability of the plasma/current sheet above streamers. We include the effects of the melon-seed force due to the overall magnetic field radial gradients on the plasmoid formed by the instability, as well as the subsequent expansion effects using the Expanding Box Model.

  13. Onset of fingering instability in a finite slice of adsorbed solute

    CERN Document Server

    Hota, Tapan Kumar; Mishra, Manoranjan


    The effect of a linear adsorption isotherm on the onset of fingering instability in a miscible displacement in the application of liquid chromatography, pollutant contamination in aquifers etc. is investigated. Such fingering instability on the solute dynamics arise due to the miscible viscus fingering (VF) between the displacing fluid and sample solvent. We use a Fourier pseudo-spectral method to solve the initial value problem appeared in the linear stability analysis. The present linear stability analysis is of generic type and it captures the early time diffusion dominated region which was never expressible through the quasi-steady state analysis (QSSA). In addition, it measures the onset of instability more accurately than the QSSA methods. It is shown that the onset time depends non-monotonically on the retention parameter of the solute adsorption. This qualitative influence of the retention parameter on the onset of instability resemblances with the results obtained from direct numerical simulations of...

  14. The gravity wave instability induced by photochemistry in summer polar mesopause region

    Institute of Scientific and Technical Information of China (English)


    The effect of diabatic process due to the photochemical heating and cooling on the gravity wave propagation in middle atmosphere is studied. A linear gravity wave model which considers the diabatic process is established. The unstable region and the growth rate of the gravity wave caused by photochemistry are calculated. And the comparison between the model and the adiabatic gravity wave theory of pure dynamics is made. The results indicate that the photochemical heating process can induce the instability of gravity wave at mesopause. The intensity of the instability becomes stronger as the temperature decreases. The temperature feature and the altitude characteristics of the instability are consistent with the observation. Therefore, the instability of the gravity wave induced by photochemistry may be an important mechanism in polar mesopause region in summer.

  15. Large-Scale Gravitational Instability and Star Formation in the Large Magellanic Cloud

    CERN Document Server

    Yang, Chao-Chin; Chu, You-Hua; Mac Low, Mordecai-Mark; Fukui, Yasuo


    Large-scale star formation in disk galaxies is hypothesized to be driven by global gravitational instability. The observed gas surface density is commonly used to compute the strength of gravitational instability, but according to this criterion star formation often appears to occur in gravitationally stable regions. One possible reason is that the stellar contribution to the instability has been neglected. We have examined the gravitational instability of the Large Magellanic Cloud (LMC) considering the gas alone, and considering the combination of collisional gas and collisionless stars. We compare the gravitationally unstable regions with the on-going star formation revealed by Spitzer observations of young stellar objects. Although only 62% of the massive young stellar object candidates are in regions where the gas alone is unstable, some 85% lie in regions unstable due to the combination of gas and stars. The combined stability analysis better describes where star formation occurs. In agreement with othe...

  16. Nonlinear electron-magnetohydrodynamic simulations of three dimensional current shear instability

    Energy Technology Data Exchange (ETDEWEB)

    Jain, Neeraj [Max Planck Institute for Solar System Research, Max-Planck-Str. 2, 37191 Katlenburg-Lindau (Germany); Das, Amita; Sengupta, Sudip; Kaw, Predhiman [Institute for Plasma Research, Bhat, Gandhinagar 382428 (India)


    This paper deals with detailed nonlinear electron-magnetohydrodynamic simulations of a three dimensional current shear driven instability in slab geometry. The simulations show the development of the instability in the current shear layer in the linear regime leading to the generation of electromagnetic turbulence in the nonlinear regime. The electromagnetic turbulence is first generated in the unstable shear layer and then spreads into the stable regions. The turbulence spectrum shows a new kind of anisotropy in which power transfer towards shorter scales occurs preferentially in the direction perpendicular to the electron flow. Results of the present three dimensional simulations of the current shear instability are compared with those of our earlier two dimensional simulations of sausage instability. It is found that the flattening of the mean velocity profile and thus reduction in the electron current due to generation of electromagnetic turbulence in the three dimensional case is more effective as compared to that in the two dimensional case.

  17. Higher-order splitting algorithms for solving the nonlinear Schr\\"odinger equation and their instabilities

    CERN Document Server

    Chin, Siu A


    Since the kinetic and the potential energy term of the real time nonlinear Schr\\"odinger equation can each be solved exactly, the entire equation can be solved to any order via splitting algorithms. We verified the fourth-order convergence of some well known algorithms by solving the Gross-Pitaevskii equation numerically. All such splitting algorithms suffer from a latent numerical instability even when the total energy is very well conserved. A detail error analysis reveals that the noise, or elementary excitations of the nonlinear Schr\\"odinger, obeys the Bogoliubov spectrum and the instability is due to the exponential growth of high wave number noises caused by the splitting process. For a continuum wave function, this instability is unavoidable no matter how small the time step. For a discrete wave function, the instability can be avoided only for $\\dt k_{max}^2{<\\atop\\sim}2 \\pi$, where $k_{max}=\\pi/\\Delta x$.

  18. Instability of counter-rotating stellar disks (United States)

    Hohlfeld, R. G.; Lovelace, R. V. E.


    We use an N-body simulation, constructed using GADGET-2, to investigate an accretion flow onto an astrophysical disk that is in the opposite sense to the disk's rotation. In order to separate dynamics intrinsic to the counter-rotating flow from the impact of the flow onto the disk, we consider an initial condition in which the counter-rotating flow is in an annular region immediately exterior the main portion of the astrophysical disk. Such counter-rotating flows are seen in systems such as NGC 4826 (known as the "Evil Eye Galaxy"). Interaction between the rotating and counter-rotating components is due to two-stream instability in the boundary region. A multi-armed spiral density wave is excited in the astrophysical disk and a density distribution with high azimuthal mode number is excited in the counter-rotating flow. Density fluctuations in the counter-rotating flow aggregate into larger clumps and some of the material in the counter-rotating flow is scattered to large radii. Accretion flow processes such as this are increasingly seen to be of importance in the evolution of multi-component galactic disks.

  19. Multidimensional Simulations of Rotating Pair Instability Supernovae

    CERN Document Server

    Chatzopoulos, E; Couch, S M


    We study the effects of rotation on the dynamics, energetics and Ni-56 production of Pair Instability Supernova explosions by performing rotating two-dimensional ("2.5-D") hydrodynamics simulations. We calculate the evolution of eight low metallicity (Z = 10^-3, 10^-4 Zsun) massive (135-245 Msun) PISN progenitors with initial surface rotational velocities 50% that of the critical Keplerian value using the stellar evolution code MESA. We allow for both the inclusion and the omission of the effects of magnetic fields in the angular momentum transport and in chemical mixing, resulting in slowly-rotating and rapidly-rotating final carbon-oxygen cores, respectively. Increased rotation for carbon-oxygen cores of the same mass and chemical stratification leads to less energetic PISN explosions that produce smaller amounts of Ni-56 due to the effect of the angular momentum barrier that develops and slows the dynamical collapse. We find a non-monotonic dependence of Ni-56 production on rotational velocity in situation...

  20. Streak instability induced by bedload diffusion (United States)

    Abramian, Anaïs; Seizilles, Grégoire; Devauchelle, Olivier; Lajeunesse, Eric


    The bed of an alluvial river is made of the sediment it transports. Its shape and size are controlled mostly by bedload transport which, at first order, entrains sediment grains along the flow. Gravity also pulls the moving grains towards the center of the channel, thus eroding the banks continually (Parker 1978). However, laboratory observations show that, due to the bed roughness, the trajectory of a transported grain fluctuates in the transverse direction (Seizilles et al. 2014). The bedload layer is therefore a collection of random walkers which diffuse towards the less active areas of the bed. In a river at equilibrium, bedload diffusion counteracts gravity to maintain the banks. If an initially flat bed of sediment is perturbed with longitudinal streaks, the flow-induced shear stress is weaker where the flow is shallower. Therefore, we expect bedload diffusion to induce a flux of sediment towards the crests of the perturbation. This positive feedback induces an instability which can generate new channels. We suggest that this mechanism could explain the transition from a single-thread river to a braided one.